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Sample records for recoil mass separator

  1. Nuclear astrophysics studies by recoil mass separators.

    NASA Astrophysics Data System (ADS)

    Gialanella, L.; Brand, K.; Campajola, L.; D'Onofrio, A.; Greife, U.; Morone, M. C.; Oliviero, G.; Ordine, A.; Roca, V.; Rolfs, C.; Romano, M.; Romoli, M.; Schmidt, S.; Schulte, W. H.; Strieder, F.; Terrasi, F.; Trautvetter, H. P.; Zahnow, D.

    1997-11-01

    It has been recently demonstrated that an accelerator mass spectrometry (AMS) system, used as a recoil separator in conjunction with a windowless gas target, can yield the high suppression factor needed to dispersively analyze radiative capture residues, with the aim of measuring cross sections in the sub-microbarn range. An experiment is underway utilizing a radioactive 7Be beam for the measurement of the cross section of the astrophysically important reaction 7Be(p, γ)8B at a center of mass energy ECM = 1 MeV. Preliminary results of this experiment are presented. The extension of the method to another reaction playing a key role in stellar evolution, i.e. 12C(α, γ)16O, requires an improvement of the angle- and momentum-acceptance of the recoil separator, the use of a jet gas target and of a specially designed low-threshold detector. The solutions proposed by a joint Italian-German project are discussed.

  2. Design of the recoil mass separator St. George

    NASA Astrophysics Data System (ADS)

    Couder, M.; Berg, G. P. A.; Görres, J.; LeBlanc, P. J.; Lamm, L. O.; Stech, E.; Wiescher, M.; Hinnefeld, J.

    2008-03-01

    A recoil mass separator has been designed for the purpose of studying low energy (α,γ) reactions in inverse kinematics for beam masses up to about A=40. Their reaction rates are of importance for our understanding of energy production and nucleosynthesis during stellar and explosive helium burning. The reactions take place in a windowless He gas target at the beginning of the separator which consists of three sections. The first section selects the most abundant charge state. The Wien filter in the second section efficiently separates the intense beam from the few reaction products. In the last section the reaction products are focused into a detector system consisting of time pickup and energy detectors. In order to accept the complete kinematic cone of recoil particles for energies as low as reasonably possible we specified a large circular angular acceptance of ±40 mrad. This requires a careful minimization of higher-order aberrations. The present system has been designed to allow for a future upgrade to extend the experimental program to the analysis of (p,γ) reactions.

  3. Sub-barrier reactions measured using a recoil mass separator

    SciTech Connect

    Betts, R.R.

    1988-01-01

    Few data exist in the sub-barrier region for reaction channels other than fusion. In particular, our experimental knowledge of quasi-elastic transfer reactions is sparse, despite the belief that this particular channel may be dominant in determining some features of the sub-barrier fusion enhancement. Transfer reactions are governed primarily by the closet approach of the colliding nuclei which, at low energies, results in a strong backward peaking of the angular distribution in the center-of-mass frame. For situations where the projectile has a significant fraction of the target mass, as is so in most cases of interest, the backscattered projectile-like fragment has such low energy that the usual techniques of measurement and identification become invalid. Here, we report on a solution to this problem which allows a systematic study of many aspects of transfer reactions in the energy regime of interest. We exploit the fact that associated with the low-energy backscattered projectile-like fragment is a complementary target-like fragment which recoils to forward angles with a large fraction of the incident beam energy. These target-like fragments were detected and identified using the Daresbury Recoil Mass Separator thus allowing the measurement of quasi-elastic transfer over hitherto inaccessible energy range from the vicinity of the barrier to several tens of MeV below. The experiments described here used VYNi beams of energies ranging from 180 to 260 MeV provided by the Daresbury Laboratory Nuclear Structure Facility tandem accelerator. Data on sub-barrier transfer for targets of /sup 116,118,120,122,124/Sn and /sup 144,148,150,152,154/Sm were obtained. 16 refs., 10 figs., 2 tabs.

  4. COSY Simulations to Guide Commissioning of the St. George Recoil Mass Separator

    NASA Astrophysics Data System (ADS)

    Schmitt, Jaclyn; Moran, Michael; Seymour, Christopher; Gilardy, Gwenaelle; Meisel, Zach; Couder, Manoel

    2015-10-01

    The goal of St. George (STrong Gradient Electromagnetic Online Recoil separator for capture Gamma ray Experiments) is to measure (α, γ) cross sections relevant to stellar helium burning. Recoil separators such as St. George are able to more closely approach the low astrophysical energies of interest because they collect reaction recoils rather than γ-rays, and thus are not limited by room background. In order to obtain an accurate cross section measurement, a recoil separator must be able to collect all recoils over their full range of expected energy and angular spread. The energy acceptance of St. George is currently being measured, and the angular acceptance will be measured soon. Here we present the results of COSY ion optics simulations and magnetic field analyses which were performed to help guide the commissioning measurements and diagnostic upgrades required to complete those measurements. National Science Foundation Research Experiences for Undergraduates program.

  5. Recoil Separators for Nuclear Astrophysics

    NASA Astrophysics Data System (ADS)

    Blackmon, J. C.

    2004-10-01

    Hydrogen and helium capture reactions are important in many astrophysical environments. Measurements in inverse kinematics using recoil separators have demonstrated a particularly sensitive technique for studying low-yield capture reactions.(M. S. Smith, C. E. Rolfs, and C. A. Barnes, Nucl. Instrum. Meth. Phys. Res. A306) (1991) 233. This approach allows a low background rate to be achieved with a high detection efficiency (about 50%) for the particles of interest using a device with only modest acceptance. Recoil separators using a variety of ion-optic configurations have been installed at numerous accelerator facilities in the past decade and have been used to measure, for example, alpha capture reactions using stable beams(D. Rogalla et al.), Eur. Phys. J. 6 (1999) 471. and proton capture reactions using radioactive ion beams.(S. Bishop et al.), Phys. Rev. Lett. 90 (2003) 162501. Measurements in inverse kinematics are the only viable means for studying reactions on short-lived nuclei that are crucial for understanding stellar explosions, and a recoil separator optimized for the measurement of capture reactions with radioactive ion beams figures prominently into the design of the low energy experimental area at the Rare Isotope Accelerator (RIA). The operational requirements for such a device will be outlined, and recoil separator designs and characteristics will be presented.

  6. A recoil separator for nuclear astrophysics SECAR

    NASA Astrophysics Data System (ADS)

    Berg, G. P. A.; Bardayan, D. W.; Blackmon, J. C.; Chipps, K. A.; Couder, M.; Greife, U.; Hager, U.; Montes, F.; Rehm, K. E.; Schatz, H.; Smith, M. S.; Wiescher, M.; Wrede, C.; Zeller, A.

    2016-06-01

    A recoil separator SECAR has been designed to study radiative capture reactions relevant for the astrophysical rp-process in inverse kinematics for the Facility for Rare Isotope Beams (FRIB). We describe the design, layout, and ion optics of the recoil separator and present the status of the project.

  7. Moving towards first science with the St. George recoil separator

    NASA Astrophysics Data System (ADS)

    Meisel, Zachary; Berg, G. P. A.; Gilardy, G.; Moran, M.; Schmitt, J.; Seymour, C.; Stech, E.; Couder, M.

    2015-10-01

    The St. George recoil mass separator has recently been coupled to the 5MV St. Ana accelerator at the University of Notre Dame's Nuclear Science Lab. St. George is a unique tool designed to measure radiative alpha-capture reactions for nuclei up to A = 40 in inverse kinematics in order to directly obtain cross sections required for astrophysical models of stellar and explosive helium burning. Commissioning of St. George is presently taking place with primary beams of hydrogen, helium, and oxygen. In this presentation, results will be shown for the measured energy acceptance of St. George, which compare favorably to COSY results when employing the calculated optimal ion-optical settings. Additionally, future plans will be discussed, such as assessing the angular acceptance of St. George and the re-integration of HiPPO at the separator target position to provide a dense, windowless helium gas-jet target. The material presented in this work is partially supported by the National Science Foundation Grant No. 1419765.

  8. Improvements of the DRAGON recoil separator at ISAC

    NASA Astrophysics Data System (ADS)

    Vockenhuber, C.; Buchmann, L.; Caggiano, J.; Chen, A. A.; D'Auria, J. M.; Davis, C. A.; Greife, U.; Hussein, A.; Hutcheon, D. A.; Ottewell, D.; Ouellet, C. O.; Parikh, A.; Pearson, J.; Ruiz, C.; Ruprecht, G.; Trinczek, M.; Zylberberg, J.

    2008-10-01

    The DRAGON (Detector of Recoils And Gammas Of Nuclear reactions) is used to measure radiative proton and alpha capture reaction rates involving both stable and radioactive, heavy-ion reactants at the TRIUMF-ISAC high intensity radioactive beam facility. Completed in 2001 it has been used for several challenging studies for nuclear astrophysics, e.g. 12C(α, γ)16O, 21Na(p, γ)22Mg, 26gAl(p, γ)27Si and 40Ca(α, γ)44Ti. Since initial operation, a number of improvements have been incorporated which are described here. These include a beam centering monitor based on a CCD camera, a mechanical iris to skim of beam halo, a solid state stripper acting as a charge state booster for beams with A ≳ 30, beta and gamma detectors to monitor beam intensity and to determine beam contamination in experiments with radioactive beam and the ionization chamber for both recoil identification and isobar separation.

  9. Automation of experiments at Dubna Gas-Filled Recoil Separator

    NASA Astrophysics Data System (ADS)

    Tsyganov, Yu. S.

    2016-01-01

    Approaches to solving the problems of automation of basic processes in long-term experiments in heavy ion beams of the Dubna Gas-Filled Recoil Separator (DGFRS) facility are considered. Approaches in the field of spectrometry, both of rare α decays of superheavy nuclei and those for constructing monitoring systems to provide accident-free experiment running with highly radioactive targets and recording basic parameters of experiment, are described. The specific features of Double Side Silicon Strip Detectors (DSSSDs) are considered, special attention is paid to the role of boundary effects of neighboring p-n transitions in the "active correlations" method. An example of an off-beam experiment attempting to observe Zeno effect is briefly considered. Basic examples for nuclear reactions of complete fusion at 48Ca ion beams of U-400 cyclotron (LNR, JINR) are given. A scenario of development of the "active correlations" method for the case of very high intensity beams of heavy ions at promising accelerators of LNR, JINR, is presented.

  10. Monitoring of physics performance of ILC Software based on Higgs Recoil Mass

    NASA Astrophysics Data System (ADS)

    Volkova, E.; Voutsinas, G.

    2016-02-01

    We discuss a part of ILC software development, that allow us to make automated testing of ILC results. The testing code consists of automated everyday Higgs recoil mass analysis and compares Higgs recoil mass with one of the previous day result. This code uses the result of generation, Mokka simulation and Marlin reconstruction of ILC events.

  11. Monte Carlo Simulation of the DRAGON Recoil Mass Spectrometer End Detectors

    NASA Astrophysics Data System (ADS)

    Veloce, Laurelle; Fallis, J.; Ruiz, C.; Reeve, S.

    2010-11-01

    DRAGON (Detector of Recoils And Gammas Of Nuclear reactions), located at TRIUMF in Vancouver, BC, is designed to study radiative capture reactions relevant in astrophysical nucleosynthesis processes. These types of reactions help us understand the production of heavy elements in the Universe. An accelerated beam of a given isotope is sent through a gas target where the reactions take place. Magnetic and electrostatic dipoles separate the recoils from the original beam particles, selecting particles according to charge and mass. The products of the nuclear reactions are then detected at the end of DRAGON by heavy ion detectors, which constitute two micro channel plate (MCP) detectors for time of flight measurements, used in conjunction with a Double Sided Silicon Strip Detector (DSSSD) or an ionization chamber (IC). The DSSSD gives information on number of counts, total energy deposited, and position while the IC measures the number of counts and the energy deposited as the particle travels through the chamber. In order to determine which set up is ideal for a given reaction and energy range, we have developed a Monte Carlo simulation of these end detectors. The program simulates both recoil and beam particles, and takes into account effects such as straggling and pulse height defect. Reaction kinematics in the gas target are also considered. Comparisons to recent experimental data will be discussed.

  12. Mass Separation by Metamaterials

    PubMed Central

    Restrepo-Flórez, Juan Manuel; Maldovan, Martin

    2016-01-01

    Being able to manipulate mass flow is critically important in a variety of physical processes in chemical and biomolecular science. For example, separation and catalytic systems, which requires precise control of mass diffusion, are crucial in the manufacturing of chemicals, crystal growth of semiconductors, waste recovery of biological solutes or chemicals, and production of artificial kidneys. Coordinate transformations and metamaterials are powerful methods to achieve precise manipulation of molecular diffusion. Here, we introduce a novel approach to obtain mass separation based on metamaterials that can sort chemical and biomolecular species by cloaking one compound while concentrating the other. A design strategy to realize such metamaterial using homogeneous isotropic materials is proposed. We present a practical case where a mixture of oxygen and nitrogen is manipulated using a metamaterial that cloaks nitrogen and concentrates oxygen. This work lays the foundation for molecular mass separation in biophysical and chemical systems through metamaterial devices. PMID:26912419

  13. Mass Separation by Metamaterials.

    PubMed

    Restrepo-Flórez, Juan Manuel; Maldovan, Martin

    2016-01-01

    Being able to manipulate mass flow is critically important in a variety of physical processes in chemical and biomolecular science. For example, separation and catalytic systems, which requires precise control of mass diffusion, are crucial in the manufacturing of chemicals, crystal growth of semiconductors, waste recovery of biological solutes or chemicals, and production of artificial kidneys. Coordinate transformations and metamaterials are powerful methods to achieve precise manipulation of molecular diffusion. Here, we introduce a novel approach to obtain mass separation based on metamaterials that can sort chemical and biomolecular species by cloaking one compound while concentrating the other. A design strategy to realize such metamaterial using homogeneous isotropic materials is proposed. We present a practical case where a mixture of oxygen and nitrogen is manipulated using a metamaterial that cloaks nitrogen and concentrates oxygen. This work lays the foundation for molecular mass separation in biophysical and chemical systems through metamaterial devices. PMID:26912419

  14. Mass Separation by Metamaterials

    NASA Astrophysics Data System (ADS)

    Restrepo-Flórez, Juan Manuel; Maldovan, Martin

    2016-02-01

    Being able to manipulate mass flow is critically important in a variety of physical processes in chemical and biomolecular science. For example, separation and catalytic systems, which requires precise control of mass diffusion, are crucial in the manufacturing of chemicals, crystal growth of semiconductors, waste recovery of biological solutes or chemicals, and production of artificial kidneys. Coordinate transformations and metamaterials are powerful methods to achieve precise manipulation of molecular diffusion. Here, we introduce a novel approach to obtain mass separation based on metamaterials that can sort chemical and biomolecular species by cloaking one compound while concentrating the other. A design strategy to realize such metamaterial using homogeneous isotropic materials is proposed. We present a practical case where a mixture of oxygen and nitrogen is manipulated using a metamaterial that cloaks nitrogen and concentrates oxygen. This work lays the foundation for molecular mass separation in biophysical and chemical systems through metamaterial devices.

  15. Clean recoil implantation of the 100Pd/Rh TDPAC probe using a solenoidal separator

    NASA Astrophysics Data System (ADS)

    Abiona, A. A.; Kemp, W. J.; Williams, E.; Timmers, H.

    2012-10-01

    The synthesis and recoil implantation of the 100Pd/Rh probe for time differential perturbed angular correlation (TDPAC) spectroscopy using the solenoidal reaction product separator SOLITAIRE has been demonstrated for the first time. The separator suppresses the co-implantation of the intense flux of elastically scattered projectile ions that can affect results obtained with the hyperfine interactions technique. Using three different fusion evaporation reactions, the solenoid field was optimised at 4.5 T to achieve a concentrated, circular focus of evaporation residue ions with a lateral FWHM of 20 mm. Employing the reaction 92Zr(12C,4n)100Pd several samples have been recoil-implanted with the 100Pd/Rh probe. Gamma-ray spectroscopy of a silver sample and a TDPAC measurement on zinc confirm that the new preparation technique is effective. The ratio function measured with TDPAC of an undoped germanium sample may indicate that palladium-defect pairs are absent when implanting with SOLITAIRE. However, a direct comparison with TDPAC results for germanium samples prepared with conventional recoil implantation, which does not suppress the flux of elastics, does not support this assertion.

  16. Mass and energy dispersive recoil spectrometry of MOCVD grown Al xGa 1- xAs

    NASA Astrophysics Data System (ADS)

    Walker, S. R.; Johnston, P. N.; Bubb, I. F.; Stannard, W. B.; Cohen, D. D.; Dytlewski, N.; Hult, M.; Whitlow, H. J.; Zaring, C.; Östling, M.; Andersson, M.

    1994-12-01

    Mass and energy dispersive Recoil Spectrometry (RS) has been employed to study stoichiometric variations in Al xGa 1- xAs layers. Quantitative determination of x is an important problem in the production of device materials which is not easily solved with standard techniques. Rutherford Backscattering Spectrometry (RBS) has been used extensively in semiconductor research but overlap of signals in the backscattered ion spectrum is an important limitation in the analysis of materials such as Al xGa 1- xAs which contain elements of low and similar masses. Particle Induced X-ray Emission (PIXE) analysis has good elemental resolution for this class of materials but provides little depth resolution. RS enables the determination of separate energy spectra for individual or small groups of isotopes. This allows it to be used in many situations where RBS is inappropriate. It employs a heavy ion beam to cause constituent nuclei to recoil from the target, and a Time of Flight and Energy (ToF- E) detector to detect these recoiling nuclei. Appropriate mass selection of the ToF- E data allows the determination of depth distributions for each element.

  17. Research and Development of a New Gas-Filled Recoil Separator GARIS-II

    NASA Astrophysics Data System (ADS)

    Kaji, Daiya; Morimoto, Kouji; Haba, Hiromitsu; Wakabayashi, Yasuo; Kudou, Yuki; Hung, Minghui; Goto, Shin-ichi; Murakami, Masashi; Goto, Naoya; Koyama, Takumi; Tamura, Nobuyuki; Tsuto, Shouhei; Sumita, Takayuki; Tanaka, Kengo; Takeyama, Mirei; Yamaki, Sayaka; Morita, Kosuke

    The results of the recent on-line test experiment using a gas-filled recoil ion separator GARIS-II, whose main purpose is to perform the so-called hot fusion reactions to produce superheavy elements, are presented. Reaction products via 169Tm(40Ar,4n)205Fr and 208Pb(40Ar,3n)245Fm were collected by the focal plane detection system of GARIS-II with high efficiency of 47% for 205Fr and 63% for 245Fm under low background condition.

  18. Studies of (p, γ) reactions with the Daresbury Recoil Separator at ORNL'S HRIBF

    NASA Astrophysics Data System (ADS)

    Fitzgerald, R.; Abbotoy, E.; Bardayan, D. W.; Blackmon, J. C.; Champagne, A. E.; Chen, A. A.; Greife, U.; Hill, D. W.; James, A. N.; Kozub, R. L.; Lewis, T. A.; Livesay, R.; Ma, Z.; Mahan, S. L.; McConnell, J. W.; Milner, W. T.; Moazen, B. H.; Parker, P. D.; Pierce, D. E.; Roettger, M. E.; Sahin, L.; Shapira, D.; Smith, M. S.; Strieder, F.; Swartz, K. B.; Thomas, J. S.; Visser, D. W.

    2005-02-01

    The fusion of protons with radioactive nuclei is important in stellar explosions such as novae and X-ray bursts and for the production of neutrinos in the sun. The Daresbury Recoil Separator and a windowless gas target system have been installed at ORNL's Holifield Radioactive Ion Beam Facility (HRIBF) for measurements of proton capture reactions in inverse kinematics with radioactive ion beams. The performance of the system has been characterized with a number of experiments using stable ion beams. We report on results from these commissioning measurements and plans for measurements of the 1H(17F,18Ne) and 1H(7Be,8B) reactions.

  19. Mass calibration of the energy axis in ToF-E elastic recoil detection analysis

    NASA Astrophysics Data System (ADS)

    Meersschaut, J.; Laricchiuta, G.; Sajavaara, T.; Vandervorst, W.

    2016-03-01

    We report on procedures that we have developed to mass-calibrate the energy axis of ToF-E histograms in elastic recoil detection analysis. The obtained calibration parameters allow one to transform the ToF-E histogram into a calibrated ToF-M histogram.

  20. Experimental Concept for a Precision Measurement of Nuclear Recoil Ionization Yields for Low Mass WIMP Searches

    NASA Astrophysics Data System (ADS)

    Saab, T.; Figueroa-Feliciano, E.

    2016-07-01

    Understanding the response of dark matter detectors at the lowest recoil energies is important for correctly interpreting data from current experiments or predicting the sensitivity of future experiments to low mass weakly interacting massive particles. In particular, the ionization yield is essential for determining the correct recoil energy of candidate nuclear recoil events; however, few measurements in cryogenic crystals exist below 1 keV. Using the voltage-assisted calorimetric ionization detection technique with a mono-energetic neutron source, we show that it is possible to determine the ionization yield in cryogenic crystals down to an energy to 100 eV. This measurement will also determine the statistics of ionization production at these low energies.

  1. Low energy nuclear recoils study in noble liquids for low-mass WIMPs

    NASA Astrophysics Data System (ADS)

    Wang, Lu; Mei, Dongming

    2014-03-01

    Detector response to low-energy nuclear recoils is critical to the detection of low-mass dark matter particles-WIMPs (Weakly interacting massive particles). Although the detector response to the processes of low-energy nuclear recoils is subtle and direct experimental calibration is rather difficult, many studies have been performed for noble liquids, NEST is a good example. However, the response of low-energy nuclear recoils, as a critical issue, needs more experimental data, in particular, with presence of electric field. We present a new design using time of flight to calibrate the large-volume xenon detector, such as LUX-Zeplin (LZ) and Xenon1T, energy scale for low-energy nuclear recoils. The calculation and physics models will be discussed based on the available data to predict the performance of the calibration device and set up criteria for the design of the device. A small test bench is built to verify the concepts at The University of South Dakota. This work is supported by DOE grant DE-FG02-10ER46709 and the state of South Dakota.

  2. Studies Of (lowercasep,γ) Reactions With The Daresbury Recoil Separator At ORNL'S HRIBF

    NASA Astrophysics Data System (ADS)

    Fitzgerald, R.; Champagne, A. E.; Visser, D. W.; Blackmon, J. C.; Bardayan, D. W.; Shapira, D.; Smith, M. S.; Kozub, R. L.; Moazen, B. H.; Parker, P. D.; Greife, U.; Livesay, R.; Ma, Z.; Jones, K. L.; Thomas, J. S.; Johnson, M. S.

    2004-10-01

    The fusion of protons with radioactive nuclei is important in stellar explosions such as novae and X-ray bursts as well as in solar neutrino production. The Daresbury Recoil Separator and a windowless gas target system have been installed at ORNL's Holifield Radioactive Ion Beam Facility (HRIBF) for measurements of proton capture reactions in inverse kinematics with radioactive ion beams. The performance of the system has been characterized with a number of experiments with stable ion beams. The windowless gas target thickness has been determined to 3% using a novel technique and the DRS transmission has been studied with ^1H(^12C,γ)^13N. Results from this work will be presented. We will also report on plans for ^1H(^7Be,γ)^8B and ^1H(^17F,γ)^18Ne measurements at the HRIBF.

  3. Simulation of Velocity Filters in the Daresbury Recoil Separator at the HRIBF

    NASA Astrophysics Data System (ADS)

    Rogers, J. P.; Kozub, R. L.; Pain, S. D.; Smith, M. S.; Bardayan, D. W.; Liu, Y.; Matos, M.

    2008-10-01

    The Daresbury Recoil Separator (DRS) at Oak Ridge National Lab's (ORNL) Holifield Radioactive Ion Beam Facility (HRIBF) is used for the study of nuclear reactions of astrophysical importance. For example, the DRS enables direct measurements of proton capture reactions on radioactive ions which occur in stellar explosions such as novae and X-ray bursts. The DRS uses velocity filters (Wien filters) that are tuned to transmit the reaction products with a specific velocity while deflecting the unreacted primary beam particles away from the optical axis, where they are stopped on adjustable slits. Data from earlier calculations of the electromagnetic fields inside and around the filters has been implemented into a FORTRAN program to provide accurate calculations and graphic representations of particle trajectories through the Wien filters. This information can be used to predetermine optimum positions of the slits for future experiments. The program will be used as an experimental setup tool for the DRS.

  4. Measurement of the W boson mass and width using a novel recoil model

    SciTech Connect

    Wetstein, Matthew J.

    2009-01-01

    This dissertation presents a direct measurement of the W boson mass (MW) and decay width (ΓW) in 1 fb-1 of W → ev collider data at D0 using a novel method to model the hadronic recoil. The mass is extracted from fits to the transverse mass MT, pT(e), and ET distributions. The width is extracted from fits to the tail of the MT distribution. The electron energy measurement is simulated using a parameterized model, and the recoil is modeled using a new technique by which Z recoils are chosen from a data library to match the pT and direction of each generated W boson. We measure the the W boson mass to be MW = 80.4035 ± 0.024(stat) ± 0.039(syst) from the MT, MW = 80.4165 ± 0.027(stat) ± 0.038(syst) from the pT(e), and MW = 80.4025 ± 0.023(stat) ± 0.043(syst) from the ET distributions. ΓW is measured to be ΓW = 2.025 ± 0.038(stat) ± 0.061(syst) GeV.

  5. Binary black hole merger gravitational waves and recoil in the large mass ratio limit

    SciTech Connect

    Sundararajan, Pranesh A.; Hughes, Scott A.; Khanna, Gaurav

    2010-05-15

    Spectacular breakthroughs in numerical relativity now make it possible to compute spacetime dynamics in almost complete generality, allowing us to model the coalescence and merger of binary black holes with essentially no approximations. The primary limitation of these calculations is now computational. In particular, it is difficult to model systems with large mass ratio and large spins, since one must accurately resolve the multiple length scales that play a role in such systems. Perturbation theory can play an important role in extending the reach of computational modeling for binary systems. In this paper, we present first results of a code that allows us to model the gravitational waves generated by the inspiral, merger, and ringdown of a binary system in which one member of the binary is much more massive than the other. This allows us to accurately calibrate binary dynamics in the large mass ratio regime. We focus in this analysis on the recoil imparted to the merged remnant by these waves. We closely examine the ''antikick,'' an antiphase cancellation of the recoil arising from the plunge and ringdown waves, described in detail by Schnittman et al. We find that, for orbits aligned with the black hole spin, the antikick grows as a function of spin. The total recoil is smallest for prograde coalescence into a rapidly rotating black hole, and largest for retrograde coalescence. Amusingly, this completely reverses the predicted trend for kick versus spin from analyses that only include inspiral information.

  6. Direct Measurements of (p,gamma) Cross Sections at Astrophysical Energies using Radioactive Beams and the Daresbury Recoil Separator

    SciTech Connect

    Bardayan, Daniel W; Chipps, K.; Fitzgerald, R. P.; Blackmon, Jeff C; Chae, K. Y.; Champagne, A. E.; Greife, U.; Hatarik, Robert; Kozub, R. L.; Matei, Catalin; Moazen, Brian; Nesaraja, Caroline D; Pain, Steven D; Peters, W. A.; Pittman, S. T.; ShrinerJr., J. F.; Smith, Michael Scott

    2009-01-01

    There are a number of astrophysical environments in which the path of nucleosynthesis leads through proton-rich nuclei. These nuclei have traditionally not been available as beams, and thus proton-capture reactions on these nuclei could only be studied indirectly. At the Holifield Radioactive Ion Beam Facility (HRIBF), some of the first direct measurements of (p,gamma) cross sections on radioactive beams have been made. The Daresbury Recoil Separator (DRS) has been used to separate the recoils of interest from the unreacted primary beam and identify them in an isobutane-filled ionization counter. First data from 17F(p,gamma)18Ne and 7B(p,gamma)8B measurements are presented.

  7. Direct measurements of (p, γ) cross-sections at astrophysical energies using radioactive beams and the Daresbury Recoil Separator

    NASA Astrophysics Data System (ADS)

    Bardayan, D. W.; Chipps, K. A.; Fitzgerald, R. P.; Blackmon, J. C.; Chae, K. Y.; Champagne, A. E.; Greife, U.; Hatarik, R.; Kozub, R. L.; Matei, C.; Moazen, B. H.; Nesaraja, C. D.; Pain, S. D.; Peters, W. A.; Pittman, S. T.; Shriner, J. F.; Smith, M. S.

    2009-12-01

    There are a number of astrophysical environments in which the path of nucleosynthesis proceeds through proton-rich nuclei. These nuclei have traditionally not been available as beams, and thus proton-capture reactions on these nuclei could only be studied indirectly. At the Holifield Radioactive Ion Beam Facility (HRIBF), some of the first direct measurements of ( p, γ) cross-sections on radioactive beams have been made. The Daresbury Recoil Separator (DRS) has been used to separate the recoils of interest from the unreacted primary beam and identify them in an isobutane-filled ionization counter. First data from 17F ( p, γ 18Ne and 7Be ( p, γ 8B measurements are presented.

  8. Direct measurments of (p,gamma) cross sections at astrophysical energies using radioactive beams and the Daresbury Recoil Separator

    SciTech Connect

    Bardayan, Daniel W; Chipps, K.; Fitzgerald, R. P.; Blackmon, Jeff C; Chae, Kyung Yuk; Champagne, A. E.; Greife, Uwe; Hatarik, Robert; Kozub, R. L.; Matei, Catalin; Moazen, Brian; Nesaraja, Caroline D; Pain, Steven D; Peters, W. A.; Pittman, S. T.; ShrinerJr., J. F.; Smith, Michael Scott

    2009-01-01

    There are a number of astrophysical environments in which the path of nucleosynthesis proceeds through proton-rich nuclei. Radioactive nuclei have traditionally not been available as beams, and thus proton-capture reactions on these nuclei could only be studied indirectly. At the Holifield Radioactive Ion Beam Facility (HRIBF), some of the first direct measurements of (p,g ) cross sections on radioactive beams have been made. The Daresbury Recoil Separator (DRS) has been used to separate the recoils of interest from the unreacted primary beam and identify them in an isobutane-filled ionization counter. Data from 17F(p,g )18Ne and 7Be(p,g )8B measurements are presented.

  9. A Monte Carlo C-code for calculating transmission efficiency of recoil separators and viewing residue trajectories

    NASA Astrophysics Data System (ADS)

    Nath, S.

    2008-10-01

    We present a semimicroscopic Monte Carlo code for calculating absolute transmission efficiency of recoil separators for heavy ion-induced complete fusion reactions. The code generates realistic distributions for energy, charge state and angle of evaporation residues. Residue trajectories are calculated using first order ion optical transfer matrices. Trajectory plots in the dispersive and the non-dispersive planes are generated. Using this code, we have obtained good agreement between calculated and measured transmission efficiencies for the Heavy Ion Reaction Analyzer at IUAC. The code can be adapted easily to any other electromagnetic recoil separator. Program summaryProgram title: TERS Catalogue identifier: AEBD_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEBD_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 6818 No. of bytes in distributed program, including test data, etc.: 1 216 097 Distribution format: tar.gz Programming language: C Computer: The code has been developed and tested on a PC with Intel Pentium IV processor Operating system: Linux RAM: About 8 Mbytes Classification: 17.7 External routines: pgplot graphics subroutine library [1] should be installed in the system for generating residue trajectory plots. Nature of problem: Recoil separators are employed to select and identify nuclei of interest, produced in a nuclear reaction, rejecting unreacted beam and other undesired reaction products. It is important to know what fraction of the selected nuclei, leaving the target, reaches the detection system. This information is crucial for determining absolute cross section of the studied reaction. Solution method:Interaction of projectiles with target nuclei is treated event by event, semimicroscopically. Position and angle (with respect to beam

  10. Optics of mass separator I

    SciTech Connect

    Balestrini, S.J.

    1981-07-01

    The ion optics of an existing mass separator are documented. The elctrostatic and magnetic stages are analyzed theoretically, both separately and in combination, by paying particular attention to the ion trajectories, the linear and angular magnifications, and the dispersion. The possibility of converting the magnet into a tunable unit by means of current-carrying elements in the gap is demonstrated. The feasibility of correction coils constructed from printed circuit board is shown.

  11. Measuring the 16O(α, γ)20Ne Reaction Rate with the Dragon Recoil Separator at Triumf

    NASA Astrophysics Data System (ADS)

    Hager, U.; Greife, U.; Buchmann, L.; Davids, B.; Fallis, J.; Hutcheon, D.; Ottewell, D.; Reeve, S.; Rojas, A.; Ruiz, C.; Sjue, S. K. L.; Erikson, L.; Carmona-Gallardo, M.; Vockenhuber, C.; Brown, J. R.; Irvine, D.

    2013-03-01

    The DRAGON recoil separator facility at TRIUMF measures radiative α and proton capture reactions of astrophysical importance in inverse kinematics. This is done employing radioactive and stable ion beams produced and accelerated using the ISAC (Isotope Separator and ACcelerator) facility in conjunction with the DRAGON windowless gas target. Over the last few years, the DRAGON collaboration has embarked on a programme to measure a variety of reactions considered vital to the understanding of various astrophysical scenarios. An overview of DRAGON's separation, beam suppression, and detection capabilities will be given. In addition, examples of recent reaction cross section measurements will be discussed, such as the 16O(α, γ)20Ne reaction, which plays an important part in the He and Ne burning in massive stars.

  12. Vacuum arc plasma mass separator

    NASA Astrophysics Data System (ADS)

    Paperny, V. L.; Krasov, V. I.; Lebedev, N. V.; Astrakchantsev, N. V.; Chernikch, A. A.

    2015-02-01

    The propagation of a metal plasma flow in a transport system with a curvilinear magnetic field was studied experimentally. The flow was generated by a pulsed vacuum arc discharge with a composite (W+Fe) cathode. The ion energy measurements at the transport system output showed that all ion components were accelerated up to equal energies per charge unit, about 150 eV and 320 eV in the outer and inner areas of the curved plasma flow, respectively. The spatial separation of the atoms of the cathode material was measured at the system output by x-ray fluorescence spectrometry. The ions of the lighter element (Fe) were concentrated in the inner part of the cathodic plasma flow deflected by the magnetic field while the distribution of the heavy element (W) was substantially shifted toward the outer area of the flow. The maximum mass separation efficiency reached 45, the effective value being 7.7. Such a system is promising for use in plasma technology for reprocessing spent nuclear fuel, namely for the separation of the heavy radioactive fission product from nuclear waste.

  13. Spectroscopy of transfermium nuclei using the GABRIELA set up at the focal plane of the VASSILISSA recoil separator

    SciTech Connect

    Hauschild, K.; Lopez-Martens, A.; Dorvaux, O.; Piot, J.; Curien, D.; Gall, B.; Yeremin, A. V.; Chelnokov, M. L.; Chepigin, V. I.; Isaev, A. V.; Izosimov, I. N.; Kabachenko, A. P.; Katrasev, D. E.; Kuznetsov, A. N.; Malyshev, O. N.; Popeko, A. G.; Sokol, E. A.; Svirikhin, A. I.; Wiborg-Hagen, T.; Nyhus, H. T

    2010-06-01

    An IN2P3-JINR collaboration has launched a project called GABRIELA at the Flerov Laboratory for Nuclear Reactions (FLNR) within the Joint Institute for Nuclear Research (JINR) in Dubna (Russia). The goal of the project is to perform gamma-ray and internal conversion electron spectroscopy of heavy nuclei produced in fusion-evaporation reactions and transported to the focal plane of the recoil separator VASSILISSA. During five experimental campaigns of GABRIELA, the detection system has gained in sensitivity and new spectroscopic information has been obtained for {sup 249}Fm, {sup 251}Fm, {sup 253}No and {sup 255}Lr. In this contribution new results for {sup 253}No will be discussed.

  14. MASS SEPARATION OF HIGH ENERGY PARTICLES

    DOEpatents

    Marshall, L.

    1962-09-25

    An apparatus and method are described for separating charged, high energy particles of equal momentum forming a beam where the particles differ slightly in masses. Magnetic lenses are utilized to focus the beam and maintain that condition while electrostatic fields located between magnetic lenses are utilized to cause transverse separation of the particles into two beams separated by a sufficient amount to permit an aperture to block one beam. (AEC)

  15. Use of the ECL-CAMAC trigger processor system for recoil missing mass triggers at the Tagged Photon Spectrometer at Fermilab

    SciTech Connect

    Martin, J.; Bracker, S.; Hartner, G.; Appel, J.; Nash, T.

    1981-05-01

    A trigger processor in operation since May 1980 at the Tagged Photon Spectrometer at Fermilab will be described. The processor, based on the Fermilab ECL-CAMAC system, allows fast selection of high mass diffractive events from the total hadronic cross section. Data from a recoil detector, consisting of 3 wire chambers and 4 layers of scintillator concentric about a 1.5 m liquid hydrogen target, is digitized and presented to the processor within 3 sec. From the chamber data are found the vertices and angles of all recoiling tracks.

  16. Alpha spectrometry applications with mass separated samples.

    PubMed

    Dion, M P; Eiden, Gregory C; Farmer, Orville T; Liezers, Martin; Robinson, John W

    2016-01-01

    (241)Am has been deposited using a novel technique that employs a commercial inductively coupled plasma mass spectrometer. This work presents results of high-resolution alpha spectrometry on the (241)Am samples using a small area passivated implanted planar silicon detector. We have also investigated the mass-based separation capability by developing a (238)Pu sample, present as a minor constituent in a (244)Pu standard, and performed subsequent radiometric counting. With this new sample development method, the (241)Am samples achieved the intrinsic energy resolution of the detector used for these measurements. There was no detectable trace of any other isotopes contained in the (238)Pu implant demonstrating the mass-based separation (or enhancement) attainable with this technique. PMID:26583262

  17. Further insight into gravitational recoil

    SciTech Connect

    Lousto, Carlos O.; Zlochower, Yosef

    2008-02-15

    We test the accuracy of our recently proposed empirical formula to model the recoil velocity imparted to the merger remnant of spinning, unequal-mass black-hole binaries. We study three families of black-hole binary configurations, all with mass ratio q=3/8 (to nearly maximize the unequal-mass contribution to the kick) and spins aligned (or counter-aligned) with the orbital angular momentum, two with spin configurations chosen to minimize the spin-induced tangential and radial accelerations of the trajectories, respectively, and a third family where the trajectories are significantly altered by spin-orbit coupling. We find good agreement between the measured and predicted recoil velocities for the first two families, and reasonable agreement for the third. We also reexamine our original generic binary configuration that led to the discovery of extremely large spin-driven recoil velocities and inspired our empirical formula, and find rough agreement between the predicted and measured recoil speeds.

  18. CHARGE BOTTLE FOR A MASS SEPARATOR

    DOEpatents

    Davidson, P.H.

    1959-07-01

    Improved mass separator charge bottles are described for containing a dense charge of a chemical compound of copper, nickel, lead or other useful substance which is to be vaporized, and to the method of utilizing such improvcd charge bottles so that the chemical compound is vaporized from the under surface of the charge and thus permits the non-volatile portion thereof to fall to the bottom of the charge bottle where it does not form an obstacle to further evaporation. The charge bottle comprises a vertically disposed cylindrical portion, an inner re-entrant cylindrical portion extending axially and downwardly into the same from the upper end thereof, and evaporative source material in the form of a chemical compound compacted within the upper annular pontion of the charge bottle formed by the re-entrant cylindrical portion, whereby vapor from the chemical compound will pass outwardly from the charge bottle through an apertured closure.

  19. Advances and problems in plasma-optical mass-separation

    SciTech Connect

    Bardakov, V. M.; Ivanov, S. D.; Strokin, N. A.

    2014-03-15

    This paper presents a short review of plasma-optical mass-separation and defines the fields for its possible application. During theoretical studies, numerical simulations, and experiments, the effect of the azimuthator finite size and of the vacuum conditions on the mass separator characteristics was revealed, as well as the quality of different-mass ion separation. The problems, solving which may lead to a successful end of the mass-separation plasma-optical technique implementation, were specified.

  20. A novel double-focusing time-of-flight mass spectrometer for absolute recoil ion cross sections measurements.

    PubMed

    Sigaud, L; de Jesus, V L B; Ferreira, Natalia; Montenegro, E C

    2016-08-01

    In this work, the inclusion of an Einzel-like lens inside the time-of-flight drift tube of a standard mass spectrometer coupled to a gas cell-to study ionization of atoms and molecules by electron impact-is described. Both this lens and a conical collimator are responsible for further focalization of the ions and charged molecular fragments inside the spectrometer, allowing a much better resolution at the time-of-flight spectra, leading to a separation of a single mass-to-charge unit up to 100 a.m.u. The procedure to obtain the overall absolute efficiency of the spectrometer and micro-channel plate detector is also discussed. PMID:27587105

  1. Low-Mass WIMP Sensitivity and Statistical Discrimination of Electron and Nuclear Recoils by Varying Luke-Neganov Phonon Gain in Semiconductor Detectors

    NASA Astrophysics Data System (ADS)

    Pyle, M.; Bauer, D. A.; Cabrera, B.; Hall, J.; Schnee, R. W.; Basu Thakur, R.; Yellin, S.

    2012-06-01

    Amplifying the phonon signal in a semiconductor dark matter detector can be accomplished by operating at high voltage bias and converting the electrostatic potential energy into Luke-Neganov phonons. This amplification method has been validated at up to | E|=40 V/cm without producing leakage in CDMS II Ge detectors, allowing sensitivity to a benchmark WIMP with mass M χ =8 GeV/c2 and σ=1.8×10-42 cm2 (with significant sensitivity for M χ >2 GeV/c2) assuming flat electronic recoil backgrounds near threshold. Furthermore, for the first time we show that differences in Luke-Neganov gain for nuclear and electronic recoils can be used to discriminate statistically between low-energy background and a hypothetical WIMP signal by operating at two distinct voltage biases. Specifically, 99% of events have p-value <10-8 for a simulated 20 kg-day experiment with a benchmark WIMP signal with M χ =8 GeV/c2 and σ=3.3×10-41 cm2.

  2. [Sublimatographic separation of fission products by beta-diketone complexes--FP chelate complexes produced directly by recoil effects (author's transl)].

    PubMed

    Nishikawa, S

    1980-03-01

    The sublimatographic separation of volatile beta-diketonate complexes of fission products produced directly by the recoil atoms of fission products under exposure of a mixture of M (beta-diketone)n and U3O8 on neutron, was carried out. When Fe(dpm)3 and Fe(pta)3 were used as the catcher chelates, both samples, the sublimated radioactive chelates located at the one zone, and the positions agreed with the deposited position of inactive each catcher chelate. The unclides presented in the zone were almost 97Zr-97Nb, 105Ru and 99Mo-99mTc. When Y(dpm)3 was used as the catcher chelates, the sublimated radioactive chelates located at the one zone, and the zone agreed with the deposited position of inactive catcher chelates, the presented nuclides in the zone were mainly 97Zr-97Nb, 95Zr-95Nb, 105Ru, 103Ru, 143Ce, 141Ce, 93Y, 92Y and 147Nd. In the case of Y(pta)3, the sublimated radioactive chelates located at the two zones. The zone at higher temperature side agreed with the deposited position of inactive catcher chelates, and the nuclides presented in this zone were the same as in the case of Y(dpm)3. On the other hand, it was observed that mainly carrier free states of 97Zr-97Nb were deposited at the zone of lower temperature side. When Ni(acac)2 was used as the catcher chelates, the sublimated radioactive chelates located at the same pattern as Y(pta)3, but the amount of deposited zones of activity was quite low. As a U3O8 target was diluted with Fe(dpm)3 catcher chelates, the yield of deposited 97Zr and 95Zr nuclides was enhanced, to about 50%. PMID:7455176

  3. The electromagnetic mass analyser EMMA

    NASA Astrophysics Data System (ADS)

    Davids, B.

    2014-01-01

    EMMA is a recoil mass spectrometer for ISAC-II at TRIUMF that will be used to separate the recoils of nuclear reactions from the beam and to disperse them according to their mass-to-charge ratios. EMMA has been designed for both efficiency and selectivity, possessing large acceptances in angle, mass, and energy without sacrificing the necessary beam suppression and mass resolving power.

  4. Plasma mass filtering for separation of actinides from lanthanides

    NASA Astrophysics Data System (ADS)

    Gueroult, R.; Fisch, N. J.

    2014-06-01

    Separating lanthanides from actinides is a key process in reprocessing nuclear spent fuel. Plasma mass filters, which operate on dissociated elements, offer conceptual advantages for such a task as compared with conventional chemical methods. The capabilities of a specific plasma mass filter concept, called the magnetic centrifugal mass filter, are analyzed within this particular context. Numerical simulations indicate separation of americium ions from a mixture of lanthanides ions for plasma densities of the order of 1012 cm-3, and ion temperatures of about 10 eV. In light of collision considerations, separating small fractions of heavy elements from a larger volume of lighter ones is shown to enhance the separation capabilities.

  5. Transport of Radioactive Material by Alpha Recoil

    SciTech Connect

    Icenhour, A.S.

    2005-05-19

    The movement of high-specific-activity radioactive particles (i.e., alpha recoil) has been observed and studied since the early 1900s. These studies have been motivated by concerns about containment of radioactivity and the protection of human health. Additionally, studies have investigated the potential advantage of alpha recoil to effect separations of various isotopes. This report provides a review of the observations and results of a number of the studies.

  6. Compact ExB mass separator for heavy ion beams

    SciTech Connect

    Wada, M.; Hashino, T.; Hirata, F.; Kasuya, T.; Sakamoto, Y.; Nishiura, M.

    2008-02-15

    A compact ExB mass separator that deflects beam by 30 deg. has been designed and built to prove its principle of operation. The main part of the separator is contained in a shielding box of 11 cm long, 9 cm wide, and 1.5 cm high. An electromagnet of 7 cm pole diameter produced variable magnetic field in the mass separation region instead of a couple of permanent magnets which is to be used in the final design. The experimental result agreed well with the theoretical prediction, and larger mass ions is bent with less magnetic field with the aid of the deflection electric field. The reduction in resolving power for mass separation due to the deflection electric field has been investigated experimentally.

  7. Recoiling from a Kick in the Head-On Case

    NASA Technical Reports Server (NTRS)

    Choi, Dae-Il; Kelly, Bernard J.; Boggs, William D.; Baker, John G.; Centrella, Joan; Van Meter, James

    2007-01-01

    Recoil "kicks" induced by gravitational radiation are expected in the inspiral and merger of black holes. Recently the numerical relativity community has begun to measure the significant kicks found when both unequal masses and spins are considered. Because understanding the cause and magnitude of each component of this kick may be complicated in inspiral simulations, we consider these effects in the context of a simple test problem. We study recoils from collisions of binaries with initially head-on trajectories, starting with the simplest case of equal masses with no spin; adding spin and varying the mass ratio, both separately and jointly. We find spin-induced recoils to be significant even in head-on configurations. Additionally, it appears that the scaling of transverse kicks with spins is consistent with post-Newtonian (PN) theory, even though the kick is generated in the nonlinear merger interaction, where PN theory should not apply. This suggests that a simple heuristic description might be effective in the estimation of spin-kicks.

  8. Separation of steroid isomers by ion mobility mass spectrometry.

    PubMed

    Ahonen, Linda; Fasciotti, Maíra; Gennäs, Gustav Boije Af; Kotiaho, Tapio; Daroda, Romeu J; Eberlin, Marcos; Kostiainen, Risto

    2013-10-01

    Ion mobility mass spectrometry performed in a compact traveling wave cell (TWIM-MS) is shown to provide a reliable, fast and repeatable method to separate derivatized steroid isomers. Three steroid isomer pairs were analyzed in their native form and as their p-toluenesulfonyl isocyanate derivatives. The native steroids were separated from each other, but no separation could be attained for the isomers. The derivatized steroid isomers were, however, properly separated by TWIM-MS with peak-to-peak resolutions close to or as high as baseline resolution (Rp-p=0.77-1.08). PMID:23992881

  9. Anatomy of the Binary Black Hole Recoil: A Multipolar Analysis

    NASA Technical Reports Server (NTRS)

    Schnittman, Jeremy; Buonanno, Alessandra; vanMeter, James R.; Baker, John G.; Boggs, William D.; Centrella, Joan; Kelly, Bernard J.; McWilliams, Sean T.

    2007-01-01

    We present a multipolar analysis of the recoil velocity computed in recent numerical simulations of binary black hole coalescence, for both unequal masses and non-zero, non-precessing spins. We show that multipole moments up to and including 1 = 4 are sufficient to accurately reproduce the final recoil velocity (= 98%) and that only a few dominant modes contribute significantly to it (2 95%). We describe how the relative amplitude, and more importantly, the relative phase, of these few modes control the way in which the recoil builds up throughout the inspiral, merger, and ring-down phases. We also find that the numerical results can be reproduced, to a high level of accuracy, by an effective Newtonian formula for the multipole moments obtained by replacing in the Newtonian formula the radial separation with an effective radius computed from the numerical data. Beyond the merger, the numerical results are reproduced by a superposition of three Kerr quasi-normal modes. Analytic formulae, obtained by expressing the multipole moments in terms of the fundamental QNMs of a Kerr BH, are able to explain the onset and amount of '.anti-kick" for each of the simulations. Lastly, we apply this multipolar analysis to understand the remarkable difference between the amplitudes of planar and non-planar kicks for equal-mass spinning black holes.

  10. Mass transfer apparatus and method for separation of gases

    DOEpatents

    Blount, Gerald C.

    2015-10-13

    A process and apparatus for separating components of a source gas is provided in which more soluble components of the source gas are dissolved in an aqueous solvent at high pressure. The system can utilize hydrostatic pressure to increase solubility of the components of the source gas. The apparatus includes gas recycle throughout multiple mass transfer stages to improve mass transfer of the targeted components from the liquid to gas phase. Separated components can be recovered for use in a value added application or can be processed for long-term storage, for instance in an underwater reservoir.

  11. First superheavy element experiments at the GSI recoil separator TASCA: The production and decay of element 114 in the {sup 244}Pu({sup 48}Ca,3-4n) reaction

    SciTech Connect

    Gates, J. M.; Duellmann, Ch. E.; Schaedel, M.; Ackermann, D.; Block, M.; Bruechle, W.; Essel, H. G.; Hartmann, W.; Hessberger, F. P.; Huebner, A.; Jaeger, E.; Khuyagbaatar, J.; Kindler, B.; Krier, J.; Kurz, N.; Lommel, B.; Schaffner, H.; Schausten, B.; Schimpf, E.; Steiner, J.

    2011-05-15

    Experiments with the new recoil separator, Transactinide Separator and Chemistry Apparatus (TASCA), at the GSI were performed by using beams of {sup 48}Ca to irradiate targets of {sup 206-208}Pb, which led to the production of {sup 252-254}No isotopes. These studies allowed for evaluation of the performance of TASCA when coupled to a new detector and electronics system. By following these studies, the isotopes of element 114 ({sup 288-291}114) were produced in irradiations of {sup 244}Pu targets with {sup 48}Ca beams at compound nucleus excitation energies around 41.7 and 37.5 MeV, demonstrating TASCA's ability to perform experiments with picobarn-level cross sections. A total of 15 decay chains were observed and were assigned to the decay of {sup 288-291}114. A new {alpha}-decay branch in {sup 281}Ds was observed, leading to the new nucleus {sup 277}Hs.

  12. The HERMES recoil detector

    NASA Astrophysics Data System (ADS)

    Airapetian, A.; Aschenauer, E. C.; Belostotski, S.; Borisenko, A.; Bowles, J.; Brodski, I.; Bryzgalov, V.; Burns, J.; Capitani, G. P.; Carassiti, V.; Ciullo, G.; Clarkson, A.; Contalbrigo, M.; De Leo, R.; De Sanctis, E.; Diefenthaler, M.; Di Nezza, P.; Düren, M.; Ehrenfried, M.; Guler, H.; Gregor, I. M.; Hartig, M.; Hill, G.; Hoek, M.; Holler, Y.; Hristova, I.; Jo, H. S.; Kaiser, R.; Keri, T.; Kisselev, A.; Krause, B.; Krauss, B.; Lagamba, L.; Lehmann, I.; Lenisa, P.; Lu, S.; Lu, X.-G.; Lumsden, S.; Mahon, D.; Martinez de la Ossa, A.; Murray, M.; Mussgiller, A.; Nowak, W.-D.; Naryshkin, Y.; Osborne, A.; Pappalardo, L. L.; Perez-Benito, R.; Petrov, A.; Pickert, N.; Prahl, V.; Protopopescu, D.; Reinecke, M.; Riedl, C.; Rith, K.; Rosner, G.; Rubacek, L.; Ryckbosch, D.; Salomatin, Y.; Schnell, G.; Seitz, B.; Shearer, C.; Shutov, V.; Statera, M.; Steijger, J. J. M.; Stenzel, H.; Stewart, J.; Stinzing, F.; Trzcinski, A.; Tytgat, M.; Vandenbroucke, A.; Van Haarlem, Y.; Van Hulse, C.; Varanda, M.; Veretennikov, D.; Vilardi, I.; Vikhrov, V.; Vogel, C.; Yaschenko, S.; Ye, Z.; Yu, W.; Zeiler, D.; Zihlmann, B.

    2013-05-01

    For the final running period of HERA, a recoil detector was installed at the HERMES experiment to improve measurements of hard exclusive processes in charged-lepton nucleon scattering. Here, deeply virtual Compton scattering is of particular interest as this process provides constraints on generalised parton distributions that give access to the total angular momenta of quarks within the nucleon. The HERMES recoil detector was designed to improve the selection of exclusive events by a direct measurement of the four-momentum of the recoiling particle. It consisted of three components: two layers of double-sided silicon strip sensors inside the HERA beam vacuum, a two-barrel scintillating fibre tracker, and a photon detector. All sub-detectors were located inside a solenoidal magnetic field with a field strength of 1T. The recoil detector was installed in late 2005. After the commissioning of all components was finished in September 2006, it operated stably until the end of data taking at HERA end of June 2007. The present paper gives a brief overview of the physics processes of interest and the general detector design. The recoil detector components, their calibration, the momentum reconstruction of charged particles, and the event selection are described in detail. The paper closes with a summary of the performance of the detection system.

  13. Ion optics system incorporating radio frequency mass separation

    NASA Technical Reports Server (NTRS)

    Anderson, John R.; Carruth, M. R., Jr.

    1990-01-01

    Results of an experimental study are presented. They show that an RF mass discriminator, based on a Bennett mass spectrometer concept, can be used to discriminate between two species of ions with about a 2-to-1 charge-to-mass ratio. Such a device would be useful for separating monatomic and diatomic oxygen ions in a system designed to simulate the environment that spacecraft encounter in low earth orbit. The influence of changing mass discriminator parameters - such as the spacing of its grids, the amplitude and frequency of RF voltage signals applied to it and the current density of ions incident upon it - on its species discrimination capabilities is discussed. Experimental results are also compared to the results of a simple theoretical model to gain insight into the processes occurring in the discriminator. These results are shown to be in good agreement.

  14. The HERMES Recoil Detector

    SciTech Connect

    Kaiser, R.

    2006-07-11

    The HERMES Collaboration is installing a new Recoil Detector to upgrade the spectrometer for measurements of hard exclusive electron/positron scattering reactions, in particular deeply virtual Compton scattering. These measurements will provide access to generalised parton distributions and hence to the localisation of quarks inside hadrons and to their orbital angular momentum. The HERMES Recoil Detector consists of three active components: a silicon detector surrounding the target cell inside the beam vacuum, a scintillating fibre tracker and a photon detector consisting of three layers of tungsten/scintillator. All three detectors are located inside a solenoidal magnetic field of 1 Tesla. The Recoil Detector was extensively tested with cosmic muons over the summer of 2005 and is being installed in the winter of 2005/6 for data taking until summer 2007.

  15. Elastic recoil detection

    NASA Astrophysics Data System (ADS)

    Bik, W. M. A.; Habraken, F. H. P. M.

    1993-07-01

    In elastic recoil detection (ERD) one determines the yield and energy of particles ejected out of the surface region of samples under MeV ion bombardment. By application of this surface and thin film analysis technique one can obtain quantitative information concerning the depth distribution of light elements in a sample to be analysed. The quantitativity and the depth resolving power are based on knowledge of the recoil cross section and the stopping power of high-energy ions in matter. This paper reviews the fundamentals of this technique and the various experimental methods for recoil identification. Furthermore, important features for material analysis, such as detection limits, depth resolution and elemental range are discussed. Some emphasis is put on the conversion of the spectral contribution of the elements to atomic concentrations in the films for several representative cases. Throughout the review numerous examples are given to illustrate the features of ERD and to demonstrate empirically the accuracy of the quantification method.

  16. High acceptance recoil polarimeter

    SciTech Connect

    The HARP Collaboration

    1992-12-05

    In order to detect neutrons and protons in the 50 to 600 MeV energy range and measure their polarization, an efficient, low-noise, self-calibrating device is being designed. This detector, known as the High Acceptance Recoil Polarimeter (HARP), is based on the recoil principle of proton detection from np[r arrow]n[prime]p[prime] or pp[r arrow]p[prime]p[prime] scattering (detected particles are underlined) which intrinsically yields polarization information on the incoming particle. HARP will be commissioned to carry out experiments in 1994.

  17. The impact of separated flow on heat and mass transfer

    SciTech Connect

    Goldstein, R.J.; Jabbari, M.Y.

    1990-01-01

    An investigation of the effect of flow separation on heat (or mass) transfer is underway. This research, sponsored by the Department of Energy (Contract No. FG02-87ER13800), is planned to enhance our understanding of the fundamental mechanisms governing the process. This report summarizes previous accomplishments and briefly describes works done during period May 1, 1989 through April 30, 1990. Future plans and studies under preparation are also mentioned. 8 refs., 7 figs.

  18. Recombination in liquid xenon for low-energy recoils

    NASA Astrophysics Data System (ADS)

    Wang, Lu; Mei, Dongming; Cubed Collaboration

    2014-09-01

    Detector response to low-energy recoils in sub-keV region is critical to detection of low-mass dark matter particles-WIMPS (Weakly interacting massive particles). The role of electron-ion recombination is important to the interpretation of the relation between ionization yield and scintillation yield, which are in general anti-correlated. Recent experimental results show that ionization yield increases down to keV range. This phenomenon contradicts general understanding for low energy recoils in the keV range in which direct excitation dominates. The explanation is that recombination becomes much less efficient when the track length is smaller than the thermalization distance of electrons. However, recombination rate is also proportional to ionization density, which is very high for keV recoils. To understand how recombination rate behaves for keV recoils, we calculated both initial recombination rate and volume recombination rate for keV recoils in liquid xenon. In this paper, we show the results of the calculated recombination rate as a function of recoil energy for both electronic recoils and nuclear recoils. Detector response to low-energy recoils in sub-keV region is critical to detection of low-mass dark matter particles-WIMPS (Weakly interacting massive particles). The role of electron-ion recombination is important to the interpretation of the relation between ionization yield and scintillation yield, which are in general anti-correlated. Recent experimental results show that ionization yield increases down to keV range. This phenomenon contradicts general understanding for low energy recoils in the keV range in which direct excitation dominates. The explanation is that recombination becomes much less efficient when the track length is smaller than the thermalization distance of electrons. However, recombination rate is also proportional to ionization density, which is very high for keV recoils. To understand how recombination rate behaves for keV recoils

  19. Is the Binary Mass Ratio Distribution Separation-Dependent?

    NASA Astrophysics Data System (ADS)

    Gullikson, Kevin; Kraus, Adam L.

    2016-01-01

    Recent discoveries of planets orbiting retired A-stars on close orbits and young A-stars on very wide orbits have renewed interest in the properties of nearby intermediate-mass stars. Especially interesting are the young stars because directly-imaged planets orbiting them may be bright enough for characterization (e.g. HR 8799, Beta Pictoris, etc). However, intermediate-mass stars and especially young intermediate mass stars are part of multiple systems more often than not. Close stellar companions may affect the formation and orbital evolution of any planets, and the properties of the companions can help constrain the binary formation mechanism. The mass ratio distribution of a population of binary stars, especially if the distribution for close companions is significantly different from that of wide companions, is helpful to distinguish companions that were born in or affected by the circumstellar disk from those which formed through fragmentation of the molecular core. Previous imaging surveys have found that binary systems with A-type primary stars tend to have cool companions with extreme mass ratios. There are hints at a much flatter mass ratio distribution for close companions, but strong completeness effects complicate the picture. We have conducted a spectroscopic survey of ~400 nearby main sequence A- and B-type stars, aimed at detecting stellar companions as late as M4 for all orbital separations <100 AU. We have searched for companions to the stars by cross-correlating the spectra against model templates for F-M type stars; a significant peak in the cross-correlation function indicates a detection. Our cross-correlation technique can detect low-mass companions with orbits that are too wide to detect with radial velocity monitoring and too small to detect with imaging techniques, making it complementary to work already done. We will present results from our survey and compare the mass ratio distribution we measure to the corresponding distribution for

  20. Combined heat and mass transfer device for improving separation process

    DOEpatents

    Tran, Thanh Nhon

    1999-01-01

    A two-phase small channel heat exchange matrix simultaneously provides for heat transfer and mass transfer between the liquid and vapor phases of a multi-component mixture at a single, predetermined location within a separation column, significantly improving the thermodynamic efficiency of the separation process. The small channel heat exchange matrix is composed of a series of channels having a hydraulic diameter no greater than 5.0 millimeters for conducting a two-phase coolant. In operation, the matrix provides the liquid-vapor contacting surfaces within the separation column, such that heat and mass are transferred simultaneously between the liquid and vapor phases. The two-phase coolant allows for a uniform heat transfer coefficient to be maintained along the length of the channels and across the surface of the matrix. Preferably, a perforated, concave sheet connects each channel to an adjacent channel to facilitate the flow of the liquid and vapor phases within the column and to increase the liquid-vapor contacting surface area.

  1. Combined heat and mass transfer device for improving separation process

    DOEpatents

    Tran, T.N.

    1999-08-24

    A two-phase small channel heat exchange matrix simultaneously provides for heat transfer and mass transfer between the liquid and vapor phases of a multi-component mixture at a single, predetermined location within a separation column, significantly improving the thermodynamic efficiency of the separation process. The small channel heat exchange matrix is composed of a series of channels having a hydraulic diameter no greater than 5.0 millimeters for conducting a two-phase coolant. In operation, the matrix provides the liquid-vapor contacting surfaces within the separation column, such that heat and mass are transferred simultaneously between the liquid and vapor phases. The two-phase coolant allows for a uniform heat transfer coefficient to be maintained along the length of the channels and across the surface of the matrix. Preferably, a perforated, concave sheet connects each channel to an adjacent channel to facilitate the flow of the liquid and vapor phases within the column and to increase the liquid-vapor contacting surface area. 12 figs.

  2. Transient Ion-Pair Separations for Electrospray Mass Spectrometry.

    PubMed

    Liu, Hanghui; Lam, Lily; Chi, Bert; Kadjo, Akinde F; Dasgupta, Purnendu K

    2016-02-16

    We report a novel ion-pair chromatography (IPC) approach for liquid chromatography electrospray ionization mass spectrometry (LC-ESI-MS), where the eluent does not contain any ion-pairing reagent (IPR). The IPR is injected on the column, much like the sample, and moves down the column. Significant amounts of a high retention factor IPR is injected, resulting in a transient but reproducible regional coating that progresses along the column. The sample is injected after a brief interval. The sample components interact with the IPR coated region during their passage; the chosen eluent gradient elutes the analytes of interest into the mass spectrometer before the IPR. Following analyte elution, the gradient is steeply raised, the IPR is washed out, and the effluent is sent to waste via a diverter valve until it is fully removed. As the nature of the analyte retention continuously changes along the column and with time, we call this transient ion-pair separation (TIPS). As the IPR never enters the MS, TIPS addresses two major drawbacks of IPC for ESI-MS: it avoids both ion suppression and ion source contamination. The potential of the generic approach for other modes of separation is discussed. An illustrative separation of two small inorganic ions, iodate and nitrate, is demonstrated on a reverse phase column by a transient prior injection of hexadecyltrimethylammonium chloride as IPR. PMID:26765166

  3. Attomole quantitation of protein separations with accelerator mass spectrometry

    SciTech Connect

    Vogel, J S; Grant, P G; Buccholz, B A; Dingley, K; Turteltaub, K W

    2000-12-15

    Quantification of specific proteins depends on separation by chromatography or electrophoresis followed by chemical detection schemes such as staining and fluorophore adhesion. Chemical exchange of short-lived isotopes, particularly sulfur, is also prevalent despite the inconveniences of counting radioactivity. Physical methods based on isotopic and elemental analyses offer highly sensitive protein quantitation that has linear response over wide dynamic ranges and is independent of protein conformation. Accelerator mass spectrometry quantifies long-lived isotopes such as 14C to sub-attomole sensitivity. We quantified protein interactions with small molecules such as toxins, vitamins, and natural biochemicals at precisions of 1-5% . Micro-proton-induced-xray-emission quantifies elemental abundances in separated metalloprotein samples to nanogram amounts and is capable of quantifying phosphorylated loci in gels. Accelerator-based quantitation is a possible tool for quantifying the genome translation into proteome.

  4. Chemical separations by bubble-assisted interphase mass-transfer.

    PubMed

    Boyd, David A; Adleman, James R; Goodwin, David G; Psaltis, Demetri

    2008-04-01

    We show that when a small amount of heat is added close to a liquid-vapor interface of a captive gas bubble in a microchannel, interphase mass-transfer through the bubble can occur in a controlled manner with only a slight change in the temperature of the fluid. We demonstrate that this method, which we refer to as bubble-assisted interphase mass-transfer (BAIM), can be applied to interphase chemical separations, e.g., simple distillation, without the need for high temperatures, vacuum, or active cooling. Although any source of localized heating could be used, we illustrate BAIM with an all-optical technique that makes use of the plasmon resonance in an array of nanoscale metal structures that are incorporated into the channel to produce localized heating of the fluid when illuminated by a stationary low-power laser. PMID:18321130

  5. Radioactive beam experiments using the Fragment Mass Analyzer

    SciTech Connect

    Davids, C.N.

    1994-04-01

    The Fragment Mass Analyzer (FMA) is a recoil mass spectrometer that has many potential applications in experiments with radioactive beams. The FMA can be used for spectroscopic studies of nuclei produced in reactions with radioactive beams. The FMA is also an ideal tool for studying radiative capture reactions of astrophysical interest, using inverse kinematics. The FMA has both mass and energy dispersion, which can be used to efficiently separate the reaction recoils from the primary beam. When used with radioactive beams, the FMA allows the recoils from radiative capture reactions to be detected in a low-background environment.

  6. Unbalance magnetron plasma source for ion mass-separator

    NASA Astrophysics Data System (ADS)

    Paperny, V. L.; Krasov, V. I.; Astrakchantsev, N. V.; Lebedev, N. V.

    2014-11-01

    The report presents the results of the preliminary studies characteristics of an unbalanced magnetron plasma source supplied with the transport system based on a curved magnetic field. The aim of these studies was to recognize if the system is suitable, in principle, for mass-separation of a multi-component plasma flow. The magnetron source has 50 mm diameter cathode manufactured of an alloy composed of Cu (64%), Pb (22.5%) and admixtures, about of 14% (Al, Zn, C). By means of an immersion time-of-flight spectrometer, a spatial distribution of ions of the cathode material was measured through the system output cross-section. Distribution of atom of these elements was measured here by the X-ray fluorescence spectrometry as well. Both methods showed that the ions of the lighter element (Cu) were concentrated in the inner part of the plasma flow deflected by the magnetic field while the distribution of the heavy element (Pb) was shifted toward the outer area of the flow. The similar effect was observed for each couple of the elements. Such a system is promising for use in plasma technology of reprocessing spent nuclear fuel, namely for separation heavy radioactive fission product from nuclear waste.

  7. Recoil-α-fission and recoil-α-α-fission events observed in the reaction 48Ca + 243Am

    NASA Astrophysics Data System (ADS)

    Forsberg, U.; Rudolph, D.; Andersson, L.-L.; Di Nitto, A.; Düllmann, Ch. E.; Fahlander, C.; Gates, J. M.; Golubev, P.; Gregorich, K. E.; Gross, C. J.; Herzberg, R.-D.; Heßberger, F. P.; Khuyagbaatar, J.; Kratz, J. V.; Rykaczewski, K.; Sarmiento, L. G.; Schädel, M.; Yakushev, A.; Åberg, S.; Ackermann, D.; Block, M.; Brand, H.; Carlsson, B. G.; Cox, D.; Derkx, X.; Dobaczewski, J.; Eberhardt, K.; Even, J.; Gerl, J.; Jäger, E.; Kindler, B.; Krier, J.; Kojouharov, I.; Kurz, N.; Lommel, B.; Mistry, A.; Mokry, C.; Nazarewicz, W.; Nitsche, H.; Omtvedt, J. P.; Papadakis, P.; Ragnarsson, I.; Runke, J.; Schaffner, H.; Schausten, B.; Shi, Yue; Thörle-Pospiech, P.; Torres, T.; Traut, T.; Trautmann, N.; Türler, A.; Ward, A.; Ward, D. E.; Wiehl, N.

    2016-09-01

    Products of the fusion-evaporation reaction 48Ca + 243Am were studied with the TASISpec set-up at the gas-filled separator TASCA at the GSI Helmholtzzentrum für Schwerionenforschung, Darmstadt, Germany. Amongst the detected thirty correlated α-decay chains associated with the production of element Z = 115, two recoil-α-fission and five recoil- α- α-fission events were observed. The latter five chains are similar to four such events reported from experiments performed at the Dubna gas-filled separator, and three such events reported from an experiment at the Berkeley gas-filled separator. The four chains observed at the Dubna gas-filled separator were assigned to start from the 2n-evaporation channel 289115 due to the fact that these recoil- α- α-fission events were observed only at low excitation energies. Contrary to this interpretation, we suggest that some of these recoil- α- α-fission decay chains, as well as some of the recoil- α- α-fission and recoil-α-fission decay chains reported from Berkeley and in this article, start from the 3n-evaporation channel 288115.

  8. Interpreting Recoil for Undergraduate Students

    ERIC Educational Resources Information Center

    Elsayed, Tarek A.

    2012-01-01

    The phenomenon of recoil is usually explained to students in the context of Newton's third law. Typically, when a projectile is fired, the recoil of the launch mechanism is interpreted as a reaction to the ejection of the smaller projectile. The same phenomenon is also interpreted in the context of the conservation of linear momentum, which is…

  9. In-beam separation and mass determination of superheavy nuclei. Part II

    NASA Astrophysics Data System (ADS)

    Malyshev, O. N.; Yeremin, A. V.; Popeko, A. G.; Belozerov, A. V.; Chelnokov, M. L.; Chepigin, V. I.; Gorshkov, V. A.; Hofmann, S.; Itkis, M. G.; Kabachenko, A. P.; Oganessian, Yu. Ts.; Sagaidak, R. N.; Šáro, Š.; Shutov, A. V.; Svirikhin, A. I.

    2004-01-01

    Within the past 15 years, the recoil separator VASSILISSA has been used for the investigations of evaporation residues produced in complete fusion reactions induced by heavy ions. The study of decay properties and formation of cross-sections of the isotopes of elements 110, 112 and 114 was performed using high-intensity 48Ca beams and 232Th, 238U, 242Pu targets. For further experiments aimed at the synthesis of the superheavy element isotopes ( Z⩾110) with the use of intense 48Ca extracted beams, improvements in the ion optical system of the separator and the focal plane detector system have been made. The results from the test reactions and new results for the isotope 283112 are presented.

  10. Recoil Based Fuel Breeding Fuel Structure

    SciTech Connect

    Popa-Simil, Liviu

    2008-07-01

    Nuclear transmutation reactions are based on the absorption of a smaller particle as neutron, proton, deuteron, alpha, etc. The resulting compound nucleus gets out of its initial lattice mainly by taking the recoil, also with help from its sudden change in chemical properties. The recoil implantation is used in correlation with thin and ultra thin materials mainly for producing radiopharmaceuticals and ultra-thin layer radioactive tracers. In nuclear reactors, the use of nano-particulate pellets could facilitate the recoil implantation for breeding, transmutation and partitioning purposes. Using enriched {sup 238}U or {sup 232}Th leads to {sup 239}Pu and {sup 233}U production while using other actinides as {sup 240}Pu, {sup 241}Am etc. leads to actinide burning. When such a lattice is immersed into a radiation resistant fluid (water, methanol, etc.), the recoiled product is transferred into the flowing fluid and removed from the hot area using a concentrator/purifier, preventing the occurrence of secondary transmutation reactions. The simulation of nuclear collision and energy transfer shows that the impacted nucleus recoils in the interstitial space creating a defect or lives small lattices. The defect diffuses, and if no recombination occurs it stops at the lattices boundaries. The nano-grains are coated in thin layer to get a hydrophilic shell to be washed by the collection liquid the particle is immersed in. The efficiency of collection depends on particle magnitude and nuclear reaction channel parameters. For {sup 239}Pu the direct recoil extraction rate is about 70% for {sup 238}UO{sub 2} grains of 5 nm diameters and is brought up to 95% by diffusion due to {sup 239}Neptunium incompatibility with Uranium dioxide lattice. Particles of 5 nm are hard to produce so a structure using particles of 100 nm have been tested. The particles were obtained by plasma sputtering in oxygen atmosphere. A novel effect as nano-cluster radiation damage robustness and cluster

  11. RECOILING SUPERMASSIVE BLACK HOLES IN SPIN-FLIP RADIO GALAXIES

    SciTech Connect

    Liu, F. K.; Wang Dong; Chen Xian

    2012-02-20

    Numerical relativity simulations predict that coalescence of supermassive black hole (SMBH) binaries leads not only to a spin flip but also to a recoiling of the merger remnant SMBHs. In the literature, X-shaped radio sources are popularly suggested to be candidates for SMBH mergers with spin flip of jet-ejecting SMBHs. Here we investigate the spectral and spatial observational signatures of the recoiling SMBHs in radio sources undergoing black hole spin flip. Our results show that SMBHs in most spin-flip radio sources have mass ratio q {approx}> 0.3 with a minimum possible value q{sub min} {approx_equal} 0.05. For major mergers, the remnant SMBHs can get a kick velocity as high as 2100 km s{sup -1} in the direction within an angle {approx}< 40 Degree-Sign relative to the spin axes of remnant SMBHs, implying that recoiling quasars are biased to be with high Doppler-shifted broad emission lines while recoiling radio galaxies are biased to large apparent spatial off-center displacements. We also calculate the distribution functions of line-of-sight velocity and apparent spatial off-center displacements for spin-flip radio sources with different apparent jet reorientation angles. Our results show that the larger the apparent jet reorientation angle is, the larger the Doppler-shifting recoiling velocity and apparent spatial off-center displacement will be. We investigate the effects of recoiling velocity on the dust torus in spin-flip radio sources and suggest that recoiling of SMBHs would lead to 'dust-poor' active galactic nuclei. Finally, we collect a sample of 19 X-shaped radio objects and for each object give the probability of detecting the predicted signatures of recoiling SMBH.

  12. Photodissociation of methyl iodide at 229. 4 nm: A determination of the fragment recoil anisotropy using energy-selective electron impact ionization and time-of-flight mass spectrometry

    SciTech Connect

    Penn, S.M.; Hayden, C.C.; Carlson Muyskens, K.J.; Crim, F.F.

    1988-09-01

    Energy-selective electron impact ionization of laser-produced photofragments together with time-of-flight mass spectrometry is a general and sensitive means of studying primary photodissociation processes. Low-energy electrons ionize photofragments without the production of background fragment ions from dissociative ionization of the parent molecules, and the time-of-flight mass spectral peak shapes provide direct information on the photofragment recoil anisotropy. In the first application of this combination of techniques, we have studied the photodissociation of methyl iodide at 229.4 nm, the short-wavelength end of the A band, in order to assess the contribution of transitions to the /sup 1/Q/sub 1/ state to the absorption profile. The results presented here show that I(/sup 2/P/sub 1//sub ///sub 2/) is the primary iodine--atom product and that the transition is largely parallel (..beta.. = (1.6 +- 0.1) for I(/sup 2/P/sub 1//sub ///sub 2/)) at 229.4 nm. These data together with previous photofragmentation results suggest that excitation to the /sup 3/Q/sub 0/ state dominates the entire A band absorption profile.

  13. Radio-frequency ion deflector for mass separation

    SciTech Connect

    Schlösser, Magnus Rudnev, Vitaly; Ureña, Ángel González

    2015-10-15

    Electrostatic cylindrical deflectors act as energy analyzer for ion beams. In this article, we present that by imposing of a radio-frequency modulation on the deflecting electric field, the ion transmission becomes mass dependent. By the choice of the appropriate frequency, amplitude, and phase, the deflector can be used as mass filter. The basic concept of the new instrument as well as simple mathematic relations are described. These calculations and further numerical simulations show that a mass sensitivity is achievable. Furthermore, we demonstrate the proof-of-principle in experimental measurements, compare the results to those of from a 1 m linear time-of-flight spectrometer, and comment on the mass resolution of the method. Finally, some potential applications are indicated.

  14. Radio-frequency ion deflector for mass separation.

    PubMed

    Schlösser, Magnus; Rudnev, Vitaly; González Ureña, Ángel

    2015-10-01

    Electrostatic cylindrical deflectors act as energy analyzer for ion beams. In this article, we present that by imposing of a radio-frequency modulation on the deflecting electric field, the ion transmission becomes mass dependent. By the choice of the appropriate frequency, amplitude, and phase, the deflector can be used as mass filter. The basic concept of the new instrument as well as simple mathematic relations are described. These calculations and further numerical simulations show that a mass sensitivity is achievable. Furthermore, we demonstrate the proof-of-principle in experimental measurements, compare the results to those of from a 1 m linear time-of-flight spectrometer, and comment on the mass resolution of the method. Finally, some potential applications are indicated. PMID:26520948

  15. Laser vaporization/ionization interface for coupling microscale separation techniques with mass spectrometry

    DOEpatents

    Yeung, Edward S.; Chang, Yu-chen

    1999-06-29

    The present invention provides a laser-induced vaporization and ionization interface for directly coupling microscale separation processes to a mass spectrometer. Vaporization and ionization of the separated analytes are facilitated by the addition of a light-absorbing component to the separation buffer or solvent.

  16. Laser vaporization/ionization interface for coupling microscale separation techniques with mass spectrometry

    DOEpatents

    Yeung, E.S.; Chang, Y.C.

    1999-06-29

    The present invention provides a laser-induced vaporization and ionization interface for directly coupling microscale separation processes to a mass spectrometer. Vaporization and ionization of the separated analytes are facilitated by the addition of a light-absorbing component to the separation buffer or solvent. 8 figs.

  17. The project of the mass separator of atomic nuclei produced in heavy ion induced reactions

    NASA Astrophysics Data System (ADS)

    Oganessian, Yu. Ts.; Shchepunov, V. A.; Dmitriev, S. N.; Itkis, M. G.; Gulbekyan, G. G.; Khabarov, M. V.; Bekhterev, V. V.; Bogomolov, S. L.; Efremov, A. A.; Pashenko, S. V.; Stepantsov, S. V.; Yeremin, A. V.; Yavor, M. I.; Kalimov, A. G.

    2003-05-01

    A new separator and mass analyzer, named MASHA (mass analyzer of super heavy atoms), has been designed at the Flerov Laboratory JINR Dubna to separate and measure masses of nuclei and molecules with precision better than 10 -3. The set up can work in the wide mass range from A≈20 to A≈500, its mass acceptance is as large as ±2.8%. In particular, it allows unambiguous mass identification of super heavy nuclei with a resolution better than 1 amu at the level of 300 amu. Synthesized in nuclear reactions nuclides are emitted from an ECR ion source at energy E=40 kV and charge state Q=+1. Then they pass the following steps of separation and analysis: the first section of rough separation, the second section of separation and mass analysis and the final section of separation with a 90° electrostatic deflector. In the focal plane of the device, a focal plane detector determines positions (masses) of studied nuclei. Ion optics of the analyzer, optimized up to the second order, is considered. Description of its elements and subsystems is given.

  18. Mass Transport in Nanocomposite Materials for Membrane Separations

    NASA Astrophysics Data System (ADS)

    Galizia, Michele; Puccini, Ilaria; Messori, Massimo; Grazia De Angelis, Maria; Sarti, Giulio C.

    2010-06-01

    The vapor transport properties of nanocomposite materials obtained with different techniques and based on a high free volume glassy polymer suitable for membrane separations, poly[1-(trimethylsilyl)-1-propyne] (PTMSP), have been determined and modeled. The simple mixing in solution of hydrophobic fumed silica nanoparticles with PTMSP leads to mixed matrix membranes, which show higher free volume and higher values of diffusivity and permeability than the pure polymeric material. If a sol-gel route is followed, with PTMSP and Tetraethoxysylane (TEOS) as precursor of the silica phase, one obtains hybrid matrices characterized by lower vapor diffusion and sorption values with respect to the pure polymer. Although the trends observed are very regular functions of the silica content in the composite, none of the behavior observed obeys traditional models for composites permeability, such as the Maxwell's one. Both types of behaviors were modeled considering the variation of polymer fractional free volume induced by the inorganic phase: in the mixed matrices the poor interactions between silica and polymer chains favor the formation of nanovoids at the interface, increasing the free volume and the vapor diffusivity, while in the more interconnected hybrid matrices the inorganic domains act as constraints, reducing the volume occupied by the polymeric phase, which is naturally endowed with a very high excess free volume.

  19. Compact E ×B mass separator for heavy ion beamsa)

    NASA Astrophysics Data System (ADS)

    Wada, M.; Hashino, T.; Hirata, F.; Kasuya, T.; Sakamoto, Y.; Nishiura, M.

    2008-02-01

    A compact E ×B mass separator that deflects beam by 30° has been designed and built to prove its principle of operation. The main part of the separator is contained in a shielding box of 11cm long, 9cm wide, and 1.5cm high. An electromagnet of 7cm pole diameter produced variable magnetic field in the mass separation region instead of a couple of permanent magnets which is to be used in the final design. The experimental result agreed well with the theoretical prediction, and larger mass ions is bent with less magnetic field with the aid of the deflection electric field. The reduction in resolving power for mass separation due to the deflection electric field has been investigated experimentally.

  20. Atmospheric Pressure Surface Sampling/Ionization Techniques for Direct Coupling of Planar Separations with Mass Spectrometry

    SciTech Connect

    Pasilis, Sofie P; Van Berkel, Gary J

    2010-01-01

    Planar separations, which include thin layer chromatography and gel electrophoresis, are in widespread use as important and powerful tools for conducting separations of complex mixtures. To increase the utility of planar separations, new methods are needed that allow in-situ characterization of the individual components of the separated mixtures. A large number of atmospheric pressure surface sampling and ionization techniques for use with mass spectrometry have emerged in the past several years, and several have been investigated as a means for mass spectrometric read-out of planar separations. In this article, we review the atmospheric pressure surface sampling and ionization techniques that have been used for the read-out of planar separation media. For each technique, we briefly explain the operational basics and discuss the analyte type for which it is appropriate and some specific applications from the literature.

  1. Two-dimensional liquid chromatography/mass spectrometry/mass spectrometry separation of water-soluble metabolites.

    PubMed

    Fairchild, Jacob N; Horvath, Krisztian; Gooding, Jessica R; Campagna, Shawn R; Guiochon, Georges

    2010-12-24

    Off-line two-dimensional liquid chromatography with tandem mass spectrometry detection (2D-LC/MS-MS) was used to separate a set of metabolomic species. Water-soluble metabolites were extracted from Escherichia coli and Saccharomyces cerevisae cultures and were immediately analyzed using strong cation exchange (SCX)-hydrophilic interaction chromatography (HILIC). Metabolite mixtures are well-suited for multidimensional chromatography as the range of components varies widely with respect to polarity and chemical makeup. Some currently used methods employ two different separations for the detection of positively and negatively ionized metabolites by mass spectrometry. Here we developed a single set of chromatographic conditions for both ionization modes and were able to detect a total of 141 extracted metabolite species, with an overall peak capacity of ca. 2500. We show that a single two-dimensional separation method is sufficient and practical when a pair or more of unidimensional separations are used in metabolomics. PMID:21094946

  2. First operation and mass separation with the CARIBU MR-TOF

    NASA Astrophysics Data System (ADS)

    Hirsh, Tsviki Y.; Paul, Nancy; Burkey, Mary; Aprahamian, Ani; Buchinger, Fritz; Caldwell, Shane; Clark, Jason A.; Levand, Anthony F.; Ying, Lin Ling; Marley, Scott T.; Morgan, Graeme E.; Nystrom, Andrew; Orford, Rodney; Galván, Adrian Pérez; Rohrer, John; Savard, Guy; Sharma, Kumar S.; Siegl, Kevin

    2016-06-01

    The recent installation of a Multi-Reflection Time-of-Flight (MR-TOF) isobar separator at the CARIBU facility has the promising potential to significantly improve the mass separation and selection of short-lived neutron-rich beams. Ions cycled in the km-long isochronous trajectories between two electrostatic mirrors can be separated to high levels of mass-resolving power within a short time (tens of ms). The installation process is described and results from the first operation are discussed. Following an optimization of the mirror voltages a mass-resolving power of 6.8 ·104 was achieved and a separation of isobars was demonstrated. The higher purity beams provided by the MR-TOF and delivered to the Canadian Penning Trap (CPT) will provide access to further measurements of neutron-rich nuclei along the astrophysical r-process path.

  3. Delayed bunching for multi-reflection time-of-flight mass separation

    NASA Astrophysics Data System (ADS)

    Rosenbusch, M.; Chauveau, P.; Delahaye, P.; Marx, G.; Schweikhard, L.; Wienholtz, F.; Wolf, R. N.

    2015-06-01

    Many experiments are handicapped when the ion sources do not only deliver the ions of interest but also contaminations, i.e., unwanted ions of similar mass. In the recent years, multi-reflection time-of-flight mass separation has become a promising method to isolate the ions of interest from the contaminants, in particular for measurements with low-energy short-lived nuclides. To further improve the performance of multi-reflection mass separators with respect to the limitations by space-charge effects, the simultaneously trapped ions are spatially widely distributed in the apparatus. Thus, the ions can propagate with reduced Coulomb interactions until, finally, they are bunched by a change in the trapping conditions for high-resolution mass separation. Proof-of-principle measurements are presented.

  4. Delayed bunching for multi-reflection time-of-flight mass separation

    SciTech Connect

    Rosenbusch, M.; Marx, G.; Schweikhard, L.; Wienholtz, F.; Chauveau, P.; Delahaye, P.

    2015-06-29

    Many experiments are handicapped when the ion sources do not only deliver the ions of interest but also contaminations, i.e., unwanted ions of similar mass. In the recent years, multi-reflection time-of-flight mass separation has become a promising method to isolate the ions of interest from the contaminants, in particular for measurements with low-energy short-lived nuclides. To further improve the performance of multi-reflection mass separators with respect to the limitations by space-charge effects, the simultaneously trapped ions are spatially widely distributed in the apparatus. Thus, the ions can propagate with reduced Coulomb interactions until, finally, they are bunched by a change in the trapping conditions for high-resolution mass separation. Proof-of-principle measurements are presented.

  5. MASS SEPARATORS

    DOEpatents

    Oppenheimer, F.; Bell, J.W.

    1959-02-17

    An improvement in the mounting arrangement for the ion source within the vacuum tank of a calutron is presented. The entire source is supported by the vacuum envelope through the medium of a bracket secured to a removable face plate. The bracket forms a supporting platform that is generally transverse to the magnetic field. The ion generator is mounted on a pedestal-type insulator supported on the bracket, and the hot leads are brought into the vacuum envelope through a tubular elbow connected to the vacuum envelope, having the axis of its outer opening aligned with the magnetic field at which point a bushing-type insulator is employed. With this arrangement thc ion source is maintained at a positive potential with respect to the vacuum tank and the problem of electron bombardment of the insulator is considerably reduced.

  6. The Outcome of Supernovae in Massive Binaries; Removed Mass, and its Separation Dependence

    NASA Astrophysics Data System (ADS)

    Hirai, Ryosuke; Sawai, Hidetomo; Yamada, Shoichi

    2014-09-01

    The majority of massive stars are formed in binary systems. It is hence reasonable to expect that most core-collapse supernovae (CCSNe) take place in binaries and the existence of a companion star may leave some imprints in observed features. Having this in mind, we have conducted two-dimensional hydrodynamical simulations of the collisions of CCSNe ejecta with the companion star in an almost-equal-mass (~10 M ⊙) binary to find out possible consequences of such events. In particular we pay attention to the amount of mass removed and its dependence on the binary separation. In contrast to the previous surmise, we find that the companion mass is stripped not by momentum transfer but by shock heating. Up to 25% of the original mass can be removed for the closest separations and the removed mass decreases as M ubvpropa -4.3 with the binary separation a. By performing some experimental computations with artificially modified densities of incident ejecta, we show that if the velocity of ejecta is fixed, the density of incident ejecta is the single important parameter that actually determines the removed mass as Mub \\propto ρ ej 1.4. On the other hand, another set of simulations with modified velocities of incident ejecta demonstrate that the strength of the forward shock, which heats up the stellar material and causes the mass loss of the companion star, is actually the key parameter for the removed mass.

  7. In-beam studies of proton emitters using the Recoil-Decay Tagging method

    SciTech Connect

    Seweryniak, D.; Woods, P. J.; Ressler, J.; Davids, C. N.; Heinz, A.; Sonzogni, A.; Uusitalo, J.; Walters, W. B.; Caggiano, J.; Carpenter, M. P.; Cizewski, J. A.; Davinson, T.; Ding, K. Y.; Fotiades, N.; Garg, U.; Janssens, R. V. F.; Khoo, T.-L.; Kondev, F.; Lauritsen, T.; Lister, C. J.; Reiter, P.; Shergur, J.; Wiedenhoever, I.

    2000-01-19

    The last five years have witnessed a rapid increase in the volume of data on proton decaying nuclei. The path was led by decay studies with recoil mass separators equipped with double-sided Si strip detectors. The properties of many proton-decaying states were deduced, which triggered renewed theoretical interest in the process of proton decay. The decay experiments were closely followed by in-beam {gamma}-ray studies which extended one's knowledge of high-spin states of proton emitters. The unparalleled selectivity of the Recoil-Decay Tagging method combined with the high efficiency of large arrays of Ge detectors allowed, despite small cross sections and overwhelming background from strong reaction channels, the observation of excited states in several proton emitters. Recently, in-beam studies of the deformed proton emitters {sup 141}Ho and {sup 131}Eu have been performed with the GAMMASPHERE array of Ge detectors and the Fragment Mass Analyzer at ATLAS. Evidence was found for rotational bands in {sup 141}Ho and {sup 131}Eu. The deformations and the single-particle configurations proposed for the proton emitting states from the earlier proton-decay studies were confronted with the assignments deduced based on the in-beam data. It should be noted that the cross section for populating {sup 131}Eu is only about 50 nb, and it represents the weakest channel ever studied in an in-beam experiment.

  8. Optimal control of gun recoil in direct fire using magnetorheological absorbers

    NASA Astrophysics Data System (ADS)

    Singh, Harinder J.; Wereley, Norman M.

    2014-05-01

    Optimal control of a gun recoil absorber is investigated for minimizing recoil loads and maximizing rate of fire. A multi-objective optimization problem was formulated by considering the mechanical model of the recoil absorber employing a spring and a magnetorheological (MR) damper. The damper forces are predicted by evaluating pressure drops using a nonlinear Bingham-plastic model. The optimization methodology provides multiple optimal design configurations with a trade-off between recoil load minimization and increased rate of fire. The configurations with low or high recoil loads imply low or high rate of fire, respectively. The gun recoil absorber performance is also analyzed for perturbations in the firing forces. The adaptive control of the MR damper for varying gun firing forces provides a smooth operation by returning the recoil mass to its battery position (ready to reload and fire) without incurring an end-stop impact. Furthermore, constant load transmissions are observed with respect to the recoil stroke by implementing optimal control during the simulated firing events.

  9. A membrane-separator interface for mass-spectrometric analysis of blood plasma

    NASA Astrophysics Data System (ADS)

    Elizarov, A. Yu.; Gerasimov, D. G.

    2014-09-01

    We demonstrate the possibility of rapid mass-spectrometric determination of the content of anesthetic agents in blood plasma with the aid of a membrane-separator interface. The interface employs a hydrophobic selective membrane that is capable of separating various anesthetic drugs (including inhalation anesthetic sevofluran, noninhalation anesthetic thiopental, hypnotic propofol, and opioid analgesic fentanyl) from the blood plasma and introducing samples into a mass spectrometer. Analysis of the blood plasma was not accompanied by the memory effect and did not lead to membrane degradation. Results of clinical investigation of the concentration of anesthetics in the blood plasma of patients are presented.

  10. The impact of separated flow on heat and mass transfer. Final report

    SciTech Connect

    Goldstein, R.J.

    1998-08-01

    An investigation of the effect of flow separation on heat and mass transfer has been completed. This research provided enhanced understanding of fundamental mechanisms governing important heat and mass transfer flow processes. This report summarizes the work conducted under the project. This research has provided considerable new knowledge on flow and heat transfer situations of great interest in a number of energy conversion devices, including heat exchangers, gas turbines, solar energy systems and general heat transfer systems.

  11. Time-of-flight direct recoil ion scattering spectrometer

    DOEpatents

    Krauss, A.R.; Gruen, D.M.; Lamich, G.J.

    1994-09-13

    A time-of-flight direct recoil and ion scattering spectrometer beam line is disclosed. The beam line includes an ion source which injects ions into pulse deflection regions and separated by a drift space. A final optics stage includes an ion lens and deflection plate assembly. The ion pulse length and pulse interval are determined by computerized adjustment of the timing between the voltage pulses applied to the pulsed deflection regions. 23 figs.

  12. Time-of-flight direct recoil ion scattering spectrometer

    DOEpatents

    Krauss, Alan R.; Gruen, Dieter M.; Lamich, George J.

    1994-01-01

    A time of flight direct recoil and ion scattering spectrometer beam line (10). The beam line (10) includes an ion source (12) which injects ions into pulse deflection regions (14) and (16) separated by a drift space (18). A final optics stage includes an ion lens and deflection plate assembly (22). The ion pulse length and pulse interval are determined by computerized adjustment of the timing between the voltage pulses applied to the pulsed deflection regions (14) and (16).

  13. Ion exchange separation of chromium from natural water matrix for stable isotope mass spectrometric analysis

    USGS Publications Warehouse

    Ball, J.W.; Bassett, R.L.

    2000-01-01

    A method has been developed for separating the Cr dissolved in natural water from matrix elements and determination of its stable isotope ratios using solid-source thermal-ionization mass spectrometry (TIMS). The separation method takes advantage of the existence of the oxidized form of Cr as an oxyanion to separate it from interfering cations using anion-exchange chromatography, and of the reduced form of Cr as a positively charged ion to separate it from interfering anions such as sulfate. Subsequent processing of the separated sample eliminates residual organic material for application to a solid source filament. Ratios for 53Cr/52Cr for National Institute of Standards and Technology Standard Reference Material 979 can be measured using the silica gel-boric acid technique with a filament-to-filament standard deviation in the mean 53Cr/52Cr ratio for 50 replicates of 0.00005 or less. (C) 2000 Elsevier Science B.V. All rights reserved.

  14. Rapid separation of phosphopeptides by microchip electrophoresis-electrospray ionization mass spectrometry.

    PubMed

    Ollikainen, Elisa; Bonabi, Ashkan; Nordman, Nina; Jokinen, Ville; Kotiaho, Tapio; Kostiainen, Risto; Sikanen, Tiina

    2016-04-01

    Protein phosphorylation is a significant biological process, but separation of phosphorylated peptide isomers is often challenging for many analytical techniques. We developed a microchip electrophoresis (MCE) method for rapid separation of phosphopeptides with on-chip electrospray ionization (ESI) facilitating online sample introduction to the mass spectrometer (MS). With the method, two monophosphorylated positional isomers of insulin receptor peptide (IR1A and IR1B) and a triply phosphorylated insulin receptor peptide (IR3), all with the same amino acid sequence, were separated from the nonphosphorylated peptide (IR0) in less than one minute. For efficient separation of the positional peptide isomers from each other derivatization with 9-fluorenylmethyl reagents (either chloroformate, Fmoc-Cl, or N-succinimidyl carbonate, Fmoc-OSu) was required before the analysis. The derivatization improved not only the separation of the monophosphorylated positional peptide isomers in MCE, but also identification of the phosphorylation site based on MS/MS. PMID:26931427

  15. Mass Separation of Nuclear Waste Surrogates in the Archimedes Demonstration Unit

    NASA Astrophysics Data System (ADS)

    Winslow, D. L.

    2005-10-01

    The Archimedes Demonstration Unit (ADU) has successfully separated a nuclear waste surrogate into light and heavy waste streams. ADU is a large scale (L = 3.9 m, a=0.37 m) cylindrical Plasma Mass Filter^1 that utilizes perpendicular electric and magnetic fields to generate a low-pass filter on atomic mass. This technology could reduce the volume of high level nuclear waste at the Hanford site in Richland, Washington. Over the last year, several techniques have been used to evaporate and inject waste surrogates into a rotating sodium metal plasma in ADU. Both spectroscopic and material collection techniques show that the Filter reduces the amount of heavy material in the light waste stream by a factor of 20 or more, with mass collection rates of about 0.25 g/s. Results of the experimental mass separation tests, parameter scaling of the mass separation, and supporting modeling will be presented. ^1T. Ohkawa, ``Plasma Mass Filter'', U.S. Patent 6 096 220, August 1, 2000.

  16. Measurement of Nuclear Recoils in the CDMS II Dark Matter Search

    NASA Astrophysics Data System (ADS)

    Fallows, Scott M.

    The Cryogenic Dark Matter Search (CDMS) experiment is designed to directly detect elastic scatters of weakly-interacting massive dark matter particles (WIMPs), on target nuclei in semiconductor crystals composed of Si and Ge. These scatters would occur very rarely, in an overwhelming background composed primarily of electron recoils from photons and electrons, as well as a smaller but non-negligible background of WIMP-like nuclear recoils from neutrons. The CDMS~II generation of detectors simultaneously measure ionization and athermal phonon signals from each scatter, allowing discrimination against virtually all electron recoils in the detector bulk. Pulse-shape timing analysis allows discrimination against nearly all remaining electron recoils taking place near detector surfaces. Along with carefully limited neutron backgrounds, this experimental program allowed for "background-free'' operation of CDMS~II at Soudan, with less than one background event expected in each WIMP-search analysis. As a result, exclusionary upper-limits on WIMP-nucleon interaction cross section were placed over a wide range of candidate WIMP masses, ruling out large new regions of parameter space. These results, like any others, are subject to a variety of systematic effects that may alter their final interpretations. A primary focus of this dissertation will be difficulties in precisely calibrating the energy scale for nuclear recoil events like those from WIMPs. Nuclear recoils have suppressed ionization signals relative to electron recoils of the same recoil energy, so the response of the detectors is calibrated differently for each recoil type. The overall normalization and linearity of the energy scale for electron recoils in CDMS~II detectors is clearly established by peaks of known gamma energy in the ionization spectrum of calibration data from a 133Ba source. This electron-equivalent keVee) energy scale enables calibration of the total phonon signal (keVt) by enforcing unity

  17. Application of a Plasma Mass Separator to Advanced LWR Spent Fuel Reprocessing

    SciTech Connect

    Freeman, Richard; Miller, Robert; Papay, Larry; Wagoner, John; Ahlfeld, Charles; Czerwinski, Ken

    2006-07-01

    The US Department of Energy (DOE) is investigating spent fuel reprocessing for the purposes of increasing the effective capacity of a deep geological repository, reducing the radiotoxicity of waste placed in the repository and conserving nuclear fuel resources. DOE is considering hydro-chemical processing of the spent fuel after cutting the fuel cladding and fuel dissolution in nitric acid. The front end process, known as UREX, is largely based on the PUREX process and extracts U, Tc as well as fission product gases. A number of additional processing steps have become known as UREX+. One of the steps includes a further chemical treatment of remove Cs and Sr to reduce repository heat load. Other steps include successive extraction of the actinides from residual fission products, including the lanthanides. The additional UREX+ processing renders the actinides suitable for burning as reactor fuel in an advanced reactor to convert actinides to shorter-lived fission products and to produce power. New methods for separating groups of elements by their atomic mass have been developed and can be exploited to enhance spent fuel reprocessing. These physical processes dry the waste streams so that they can be vaporized and singly ionized in plasma that is contained in longitudinal magnetic and perpendicular electric fields. Proper configuration of the fields causes the plasma to rapidly rotate and expel heavier mass ions at the center of the machine. Lower mass ions form closed orbits within the cylindrical plasma column and are transported to either end of the machine. This plasma mass separator was originally developed to reduce the mass of material that must be immobilized in borosilicate glass from DOE defense waste at former weapons production facilities. The plasma mass separator appears to be well-suited for processing the UREX raffinate and solids streams by exploiting the large atomic mass gap that exists between lanthanides (< {approx}180 amu) and actinides

  18. Angular Momentum Ejection and Recoil*

    NASA Astrophysics Data System (ADS)

    Ohia, O.; Coppi, B.

    2009-11-01

    The spontaneous rotation phenomenon observed in axisymmetric magnetically confined plasmas has been explained by the ``accretion theory'' [1] that considers the plasma angular momentum as gained from its interaction with the magnetic field and the surrounding material wall. The ejection of angular momentum to the wall, and the consequent recoil are attributed to modes excited at the edge while the transport of the (recoil) angular momentum from the edge toward the center is attributed to a different kind of mode. The toroidal phase velocity of the edge mode, to which the sign of the ejected angular momentum is related, is considered to change its direction in the transition from the H-regime to the L-regime. For the latter case, edge modes with phase velocity in the direction of vdi are driven by the temperature gradient of a cold ion population at the edge and damped on the ``hot'' ion population. The ``balanced'' double interaction [2] of the mode with the two populations, corresponding to a condition of marginal stability, leads to ejection of hot ions and loss of angular momentum in the direction of vdi while the cold population acquires angular momentum in the opposite direction. In the H-regime resistive ballooning modes with phase velocities in the direction of vde are viewed as the best candidates for the excited edge modes. *Sponsored in part by the U.S. DOE. [1] B. Coppi, Nucl. Fusion 42, 1 (2002) [2] B. Coppi and F. Pegoraro, Nucl. Fusion 17, 969 (1977)

  19. The outcome of supernovae in massive binaries; removed mass, and its separation dependence

    SciTech Connect

    Hirai, Ryosuke; Sawai, Hidetomo; Yamada, Shoichi

    2014-09-01

    The majority of massive stars are formed in binary systems. It is hence reasonable to expect that most core-collapse supernovae (CCSNe) take place in binaries and the existence of a companion star may leave some imprints in observed features. Having this in mind, we have conducted two-dimensional hydrodynamical simulations of the collisions of CCSNe ejecta with the companion star in an almost-equal-mass (∼10 M {sub ☉}) binary to find out possible consequences of such events. In particular we pay attention to the amount of mass removed and its dependence on the binary separation. In contrast to the previous surmise, we find that the companion mass is stripped not by momentum transfer but by shock heating. Up to 25% of the original mass can be removed for the closest separations and the removed mass decreases as M {sub ub}∝a {sup –4.3} with the binary separation a. By performing some experimental computations with artificially modified densities of incident ejecta, we show that if the velocity of ejecta is fixed, the density of incident ejecta is the single important parameter that actually determines the removed mass as M{sub ub}∝ρ{sub ej}{sup 1.4}. On the other hand, another set of simulations with modified velocities of incident ejecta demonstrate that the strength of the forward shock, which heats up the stellar material and causes the mass loss of the companion star, is actually the key parameter for the removed mass.

  20. Mass separation of deuterium and helium with conventional quadrupole mass spectrometer by using varied ionization energy

    NASA Astrophysics Data System (ADS)

    Yu, Yaowei; Hu, Jiansheng; Wan, Zhao; Wu, Jinhua; Wang, Houyin; Cao, Bin

    2016-03-01

    Deuterium pressure in deuterium-helium mixture gas is successfully measured by a common quadrupole mass spectrometer (model: RGA200) with a resolution of ˜0.5 atomic mass unit (AMU), by using varied ionization energy together with new developed software and dedicated calibration for RGA200. The new software is developed by using MATLAB with the new functions: electron energy (EE) scanning, deuterium partial pressure measurement, and automatic data saving. RGA200 with new software is calibrated in pure deuterium and pure helium 1.0 × 10-6-5.0 × 10-2 Pa, and the relation between pressure and ion current of AMU4 under EE = 25 eV and EE = 70 eV is obtained. From the calibration result and RGA200 scanning with varied ionization energy in deuterium and helium mixture gas, both deuterium partial pressures (PD2) and helium partial pressure (PHe) could be obtained. The result shows that deuterium partial pressure could be measured if PD2 > 10-6 Pa (limited by ultimate pressure of calibration vessel), and helium pressure could be measured only if PHe/PD2 > 0.45, and the measurement error is evaluated as 15%. This method is successfully employed in EAST 2015 summer campaign to monitor deuterium outgassing/desorption during helium discharge cleaning.

  1. Mass separation of deuterium and helium with conventional quadrupole mass spectrometer by using varied ionization energy.

    PubMed

    Yu, Yaowei; Hu, Jiansheng; Wan, Zhao; Wu, Jinhua; Wang, Houyin; Cao, Bin

    2016-03-01

    Deuterium pressure in deuterium-helium mixture gas is successfully measured by a common quadrupole mass spectrometer (model: RGA200) with a resolution of ∼0.5 atomic mass unit (AMU), by using varied ionization energy together with new developed software and dedicated calibration for RGA200. The new software is developed by using MATLAB with the new functions: electron energy (EE) scanning, deuterium partial pressure measurement, and automatic data saving. RGA200 with new software is calibrated in pure deuterium and pure helium 1.0 × 10(-6)-5.0 × 10(-2) Pa, and the relation between pressure and ion current of AMU4 under EE = 25 eV and EE = 70 eV is obtained. From the calibration result and RGA200 scanning with varied ionization energy in deuterium and helium mixture gas, both deuterium partial pressures (PD2 ) and helium partial pressure (PHe) could be obtained. The result shows that deuterium partial pressure could be measured if PD2 > 10(-6) Pa (limited by ultimate pressure of calibration vessel), and helium pressure could be measured only if PHe/PD2 > 0.45, and the measurement error is evaluated as 15%. This method is successfully employed in EAST 2015 summer campaign to monitor deuterium outgassing/desorption during helium discharge cleaning. PMID:27036832

  2. A Novel method for modeling the recoil in W boson events at hadron collider

    SciTech Connect

    Abazov, Victor Mukhamedovich; Abbott, Braden Keim; Abolins, Maris A.; Acharya, Bannanje Sripath; Adams, Mark Raymond; Adams, Todd; Aguilo, Ernest; Ahsan, Mahsana; Alexeev, Guennadi D.; Alkhazov, Georgiy D.; Alton, Andrew K.; /Michigan U. /Augustana Coll., Sioux Falls /Northeastern U.

    2009-07-01

    We present a new method for modeling the hadronic recoil in W {yields} {ell}{nu} events produced at hadron colliders. The recoil is chosen from a library of recoils in Z {yields} {ell}{ell} data events and overlaid on a simulated W {yields} {ell}{nu} event. Implementation of this method requires that the data recoil library describe the properties of the measured recoil as a function of the true, rather than the measured, transverse momentum of the boson. We address this issue using a multidimensional Bayesian unfolding technique. We estimate the statistical and systematic uncertainties from this method for the W boson mass and width measurements assuming 1 fb{sup -1} of data from the Fermilab Tevatron. The uncertainties are found to be small and comparable to those of a more traditional parameterized recoil model. For the high precision measurements that will be possible with data from Run II of the Fermilab Tevatron and from the CERN LHC, the method presented in this paper may be advantageous, since it does not require an understanding of the measured recoil from first principles.

  3. Real-time 2D separation by LC × differential ion mobility hyphenated to mass spectrometry.

    PubMed

    Varesio, Emmanuel; Le Blanc, J C Yves; Hopfgartner, Gérard

    2012-03-01

    The liquid chromatography-mass spectrometry (LC-MS) analysis of complex samples such as biological fluid extracts is widespread when searching for new biomarkers as in metabolomics. The success of this hyphenation resides in the orthogonality of both separation techniques. However, there are frequent cases where compounds are co-eluting and the resolving power of mass spectrometry (MS) is not sufficient (e.g., isobaric compounds and interfering isotopic clusters). Different strategies are discussed to solve these cases and a mixture of eight compounds (i.e., bromazepam, chlorprothixene, clonapzepam, fendiline, flusilazol, oxfendazole, oxycodone, and pamaquine) with identical nominal mass (i.e., m/z 316) is taken to illustrate them. Among the different approaches, high-resolution mass spectrometry or liquid chromatography (i.e., UHPLC) can easily separate these compounds. Another technique, mostly used with low resolving power MS analyzers, is differential ion mobility spectrometry (DMS), where analytes are gas-phase separated according to their size-to-charge ratio. Detailed investigations of the addition of different polar modifiers (i.e., methanol, ethanol, and isopropanol) into the transport gas (nitrogen) to enhance the peak capacity of the technique were carried out. Finally, a complex urine sample fortified with 36 compounds of various chemical properties was analyzed by real-time 2D separation LC×DMS-MS(/MS). The addition of this orthogonal gas-phase separation technique in the LC-MS(/MS) hyphenation greatly improved data quality by resolving composite MS/MS spectra, which is mandatory in metabolomics when performing database generation and search. PMID:22006241

  4. Ion Mobility-Mass Correlation Trend Line Separation of Glycoprotein Digests without Deglycosylation

    PubMed Central

    Li, Hongli; Bendiak, Brad; Siems, William F.; Gang, David R.; Hill, Herbert H.

    2013-01-01

    A high-throughput ion mobility mass spectrometer (IMMS) was used to rapidly separate and analyze peptides and glycopeptides derived from glycoproteins. Two glycoproteins, human α-1-acid glycoprotein and antithrombin III were digested with trypsin and subjected to electrospray traveling wave IMMS analysis. No deglycosylation steps were performed; samples were complex mixtures of peptides and glycopeptides. Peptides and glycosylated peptides with different charge states (up to 4 charges) were observed and fell on distinguishable trend lines in 2-D IMMS spectra in both positive and negative modes. The trend line separation patterns matched between both modes. Peptide sequence was identified based on the corresponding extracted mass spectra and collision induced dissociated (CID) experiments were performed for selected compounds to prove class identification. The signal-to-noise ratio of the glycopeptides was increased dramatically with ion mobility trend line separation compared to non-trend line separation, primarily due to selection of precursor ion subsets within specific mobility windows. In addition, isomeric mobility peaks were detected for specific glycopeptides. IMMS demonstrated unique capabilities and advantages for investigating and separating glycoprotein digests in this study and suggests a novel strategy for rapid glycoproteomics studies in the future. PMID:23914139

  5. Binary Cepheids: Separations and Mass Ratios in 5 M ⊙ Binaries

    NASA Astrophysics Data System (ADS)

    Evans, Nancy Evans; Bond, Howard E.; Schaefer, Gail H.; Mason, Brian D.; Karovska, Margarita; Tingle, Evan

    2013-10-01

    Deriving the distribution of binary parameters for a particular class of stars over the full range of orbital separations usually requires the combination of results from many different observing techniques (radial velocities, interferometry, astrometry, photometry, direct imaging), each with selection biases. However, Cepheids—cool, evolved stars of ~5 M ⊙—are a special case because ultraviolet (UV) spectra will immediately reveal any companion star hotter than early type A, regardless of the orbital separation. We have used International Ultraviolet Explorer UV spectra of a complete sample of all 76 Cepheids brighter than V = 8 to create a list of all 18 Cepheids with companions more massive than 2.0 M ⊙. Orbital periods of many of these binaries are available from radial-velocity studies, or can be estimated for longer-period systems from detected velocity variability. In an imaging survey with the Hubble Space Telescope Wide Field Camera 3, we resolved three of the companions (those of η Aql, S Nor, and V659 Cen), allowing us to make estimates of the periods out to the long-period end of the distribution. Combining these separations with orbital data in the literature, we derive an unbiased distribution of binary separations, orbital periods, and mass ratios. The distribution of orbital periods shows that the 5 M ⊙ binaries have systematically shorter periods than do 1 M ⊙ stars. Our data also suggest that the distribution of mass ratios depends on both binary separation and system multiplicity. The distribution of mass ratios as a function of orbital separation, however, does not depend on whether a system is a binary or a triple. Based in part on observations made with the NASA/ESA Hubble Space Telescope, obtained by the Space Telescope Science Institute. STScI is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS5-26555.

  6. Intensification of heat and mass transfer by ultrasound: application to heat exchangers and membrane separation processes.

    PubMed

    Gondrexon, N; Cheze, L; Jin, Y; Legay, M; Tissot, Q; Hengl, N; Baup, S; Boldo, P; Pignon, F; Talansier, E

    2015-07-01

    This paper aims to illustrate the interest of ultrasound technology as an efficient technique for both heat and mass transfer intensification. It is demonstrated that the use of ultrasound results in an increase of heat exchanger performances and in a possible fouling monitoring in heat exchangers. Mass transfer intensification was observed in the case of cross-flow ultrafiltration. It is shown that the enhancement of the membrane separation process strongly depends on the physico-chemical properties of the filtered suspensions. PMID:25216897

  7. Star-galaxy separation strategies for WISE-2MASS all-sky infrared galaxy catalogues

    NASA Astrophysics Data System (ADS)

    Kovács, András; Szapudi, István

    2015-04-01

    We combine photometric information of the Wide-Field Infrared Survey Explorer (WISE) and Two Micron All Sky Survey (2MASS) all-sky infrared data bases, and demonstrate how to produce clean and complete galaxy catalogues for future analyses. Adding 2MASS colours to WISE photometry improves star-galaxy separation efficiency substantially at the expense of losing a small fraction of the galaxies. We find that 93 per cent of the WISE objects within W1 < 15.2 mag have a 2MASS match, and that a class of supervised machine learning algorithms, support vector machines (SVM), are efficient classifiers of objects in our multicolour data set. We constructed a training set from the Sloan Digital Sky Survey PhotoObj table with known star-galaxy separation, and determined redshift distribution of our sample from the Galaxy and Mass Assembly spectroscopic survey. Varying the combination of photometric parameters input into our algorithm we show that W1WISE - J2MASS is a simple and effective star-galaxy separator, capable of producing results comparable to the multidimensional SVM classification. We present a detailed description of our star-galaxy separation methods, and characterize the robustness of our tools in terms of contamination, completeness, and accuracy. We explore systematics of the full sky WISE-2MASS galaxy map, such as contamination from moon glow. We show that the homogeneity of the full sky galaxy map is improved by an additional J2MASS < 16.5 mag flux limit. The all-sky galaxy catalogue we present in this paper covers 21 200 deg2 with dusty regions masked out, and has an estimated stellar contamination of 1.2 per cent and completeness of 70.1 per cent among 2.4 million galaxies with zmed ≈ 0.14. WISE-2MASS galaxy maps with well controlled stellar contamination will be useful for spatial statistical analyses, including cross-correlations with other cosmological random fields, such as the cosmic microwave background. The same techniques also yield a

  8. Multidimensional Separation of Natural Products Using Liquid Chromatography Coupled to Hadamard Transform Ion Mobility Mass Spectrometry

    NASA Astrophysics Data System (ADS)

    Liu, Wenjie; Zhang, Xing; Knochenmuss, Richard; Siems, William F.; Hill, Herbert H.

    2016-05-01

    A high performance liquid chromatograph (HPLC)was interfaced to an atmospheric drift tube ion mobility time of flight mass spectrometry. The power of multidimensional separation was demonstrated using chili pepper extracts. The ambient pressure drift tube ion mobility provided high resolving powers up to 166 for the HPLC eluent. With implementation of Hadamard transform (HT), the duty cycle for the ion mobility drift tube was increased from less than 1% to 50%, and the ion transmission efficiency was improved by over 200 times compared with pulsed mode, improving signal to noise ratio 10 times. HT ion mobility and TOF mass spectrometry provide an additional dimension of separation for complex samples without increasing the analysis time compared with conventional HPLC.

  9. Multidimensional Separation of Natural Products Using Liquid Chromatography Coupled to Hadamard Transform Ion Mobility Mass Spectrometry

    NASA Astrophysics Data System (ADS)

    Liu, Wenjie; Zhang, Xing; Knochenmuss, Richard; Siems, William F.; Hill, Herbert H.

    2016-02-01

    A high performance liquid chromatograph (HPLC)was interfaced to an atmospheric drift tube ion mobility time of flight mass spectrometry. The power of multidimensional separation was demonstrated using chili pepper extracts. The ambient pressure drift tube ion mobility provided high resolving powers up to 166 for the HPLC eluent. With implementation of Hadamard transform (HT), the duty cycle for the ion mobility drift tube was increased from less than 1% to 50%, and the ion transmission efficiency was improved by over 200 times compared with pulsed mode, improving signal to noise ratio 10 times. HT ion mobility and TOF mass spectrometry provide an additional dimension of separation for complex samples without increasing the analysis time compared with conventional HPLC.

  10. Multidimensional Separation of Natural Products Using Liquid Chromatography Coupled to Hadamard Transform Ion Mobility Mass Spectrometry.

    PubMed

    Liu, Wenjie; Zhang, Xing; Knochenmuss, Richard; Siems, William F; Hill, Herbert H

    2016-05-01

    A high performance liquid chromatograph (HPLC)was interfaced to an atmospheric drift tube ion mobility time of flight mass spectrometry. The power of multidimensional separation was demonstrated using chili pepper extracts. The ambient pressure drift tube ion mobility provided high resolving powers up to 166 for the HPLC eluent. With implementation of Hadamard transform (HT), the duty cycle for the ion mobility drift tube was increased from less than 1% to 50%, and the ion transmission efficiency was improved by over 200 times compared with pulsed mode, improving signal to noise ratio 10 times. HT ion mobility and TOF mass spectrometry provide an additional dimension of separation for complex samples without increasing the analysis time compared with conventional HPLC. Graphical Abstract ᅟ. PMID:26914233

  11. Design and performance of mass-produced sideband separating SIS mixers for ALMA band 4 receivers

    NASA Astrophysics Data System (ADS)

    Kojima, Takafumi; Kuroiwa, Koichi; Takahashi, Toshikazu; Fujii, Yumi; Uzawa, Yoshinori; Asayama, Shin'ichiro; Noguchi, Takashi

    2015-09-01

    We have designed and mass-produced low-noise sideband separating superconductor-insulator-superconductor (SIS) mixers for the Atacama Large Millimeter/submillimeter Array (ALMA) band 4 over the frequency range of 125-163 GHz. An integrated design was adopted for the band 4 sideband separating (2SB) mixer block because of the advantages it offers in terms of compactness, reduced testing time and lower cost. The mixer chip was designed to be robust for handling errors to avoid performance degradation caused by generation of the higher order mode in the mixer chip slot. Detailed analyses revealed its robustness and ability to ensure mass production of the 2SB mixers. Using the robust mixer design in addition to well-established waveguide technologies, all of the 2SB mixers met ALMA specifications for noise temperature and image rejection ratio.

  12. Separation of actinides using capillary extraction chromatography-inductively coupled plasma mass spectrometry

    SciTech Connect

    Peterson, Dominic S

    2008-01-01

    Trace levels of actinides have been separated on extraction chromatography columns. Detection of the actinides was achieved using an inductively coupled plasma mass spectrometer (ICP-MS), which was coupled with the extraction chromatography system. In this study we compare 30 cm long, 4.6 mm ID columns to capillary columns (750 {micro}m ID) with lengths from 30 cm up to 150 cm. The columns that were tested were packed with TRU resin. We were able to separate a mixture of five actinides ({sup 232}Th, {sup 238}U, {sup 237}Np, {sup 239}pU, {sup 241}Am). This work has application to rapid bioassay as well as for automated separations of actinide materials.

  13. Analysis of hemodynamic fluid phase mass transport in a separated flow region.

    PubMed

    Lutostansky, Elizabeth M; Karner, Gerhard; Rappitsch, Gerhard; Ku, David N; Perktold, Karl

    2003-04-01

    The mass transfer behavior in the recirculation region downstream of an axisymmetric sudden expansion was examined. The Reynolds number, 500, and Schmidt number, 3200, were selected to model the mass transfer of molecules, such as ADP, in the arterial system. In a first step the transient mass transport applying zero diffusive flux at the wall was analyzed using experiments and two computational codes. The two codes were FLUENT, a commercially available finite volume method, and FTSP, a finite element code developed at Graz University of Technology. The comparison of the transient wall concentration values determined by the three methods was excellent and provides a measure of confidence for computational mass transfer calculations in convection dominated, separated flows. In a second step the effect of the flow separation on the stationary mass transport applying a permeability boundary condition at the water-permeable wall was analyzed using the finite element code FTSP. The results show an increase of luminal ADP surface concentration in the upstream and in the downstream tube of the sudden expansion geometry in the range of six and twelve percent of the bulk flow concentration. The effect of flow separation in the downstream tube on the wall concentration is a decrease of about ten percent of the difference between wall concentration and bulk concentration occurring at nearly fully developed flow at the downstream region at a distance of 66 downstream tube diameters from the expansion. The decrease of ADP flux into the wall is in the range of three percent of the flux at the downstream region. PMID:12751280

  14. Improvements to the on-line mass separator, RAMA, and the beta-delayed charged-particle emission of proton-rich sd shell nuclei

    SciTech Connect

    Ognibene, T.J.

    1996-03-01

    To overcome the extreme difficulties encountered in the experimental decay studies of proton drip line nuclei, several techniques have been utilized, including a helium-jet transport system, particle identification detectors and mass separation. Improvements to the ion source/extraction region of the He-jet coupled on-line Recoil Atom Mass Analyzer (RAMA) and its target/ion source coupling resulted in significant increases in RAMA efficiencies and its mass resolution, as well as reductions in the overall transit time. At the 88-Inch Cyclotron at LBNL, the decays of {sup 31}Cl, {sup 27}P and {sup 28}P, with half-lives of 150 msec, 260 msec and 270.3 msec, respectively, were examined using a he-jet and low-energy gas {Delta}E-gas {Delta}E-silicon E detector telescopes. Total beta-delayed proton branches of 0.3% and 0.07% in {sup 31}Cl and {sub 27}P, respectively, were estimated. Several proton peaks that had been previously assigned to the decay of {sup 31}Cl were shown to be from the decay of {sup 25}Si. In {sup 27}P, two proton groups at 459 {+-} 14 keV and 610 {+-} 11 keV, with intensities of 7 {+-} 3% and 92 {+-} 4% relative to the main (100%) group were discovered. The Gamow-Teller component of the preceding beta-decay of each observed proton transition was compared to results from shell model calculations. Finally, a new proton transition was identified, following the {beta}-decay of {sup 28}P, at 1,444 {+-} 12 keV with a 1.7 {+-} 0.5% relative intensity to the 100% group. Using similar low-energy detector telescopes and the mass separator TISOL at TRIUMF, the 109 msec and 173 msec activities, {sup 17}Ne and {sup 33}Ar, were studied. A new proton group with energy 729 {+-} 15 keV was observed following the beta-decay of {sup 17}Ne. Several discrepancies between earlier works as to the energies, intensities and assignments of several proton transitions from {sup 17}Ne and {sup 33}Ar were resolved.

  15. Gas powered fluid gun with recoil mitigation

    DOEpatents

    Grubelich, Mark C.; Yonas, Gerold

    2016-03-01

    A gas powered fluid gun for propelling a stream or slug of a fluid at high velocity toward a target. Recoil mitigation is provided that reduces or eliminates the associated recoil forces, with minimal or no backwash. By launching a quantity of water in the opposite direction, net momentum forces are reduced or eliminated. Examples of recoil mitigation devices include a cone for making a conical fluid sheet, a device forming multiple impinging streams of fluid, a cavitating venturi, one or more spinning vanes, or an annular tangential entry/exit.

  16. Gas powered fluid gun with recoil mitigation

    DOEpatents

    Grubelich, Mark C; Yonas, Gerold

    2013-11-12

    A gas powered fluid gun for propelling a stream or slug of a fluid at high velocity toward a target. Recoil mitigation is provided that reduces or eliminates the associated recoil forces, with minimal or no backwash. By launching a quantity of water in the opposite direction, net momentum forces are reduced or eliminated. Examples of recoil mitigation devices include a cone for making a conical fluid sheet, a device forming multiple impinging streams of fluid, a cavitating venturi, one or more spinning vanes, or an annular tangential entry/exit.

  17. Estimation of Separation Shock of the Marman Clamp System by Using a Simple Band-Mass Model

    NASA Astrophysics Data System (ADS)

    Takeuchi, Shinsuke; Onoda, Junjiro

    To prevent satellite failure during inter stage separation, the magnitude of separation shock must be estimated. The Marman Clamp System is a separation joint often used to mount satellites on a launch vehicle. This paper proposes a method of estimating separation shock for the Marman Clamp System. First, experimental results are discussed and the dominant parameters of separation shock are identified for the system. Next, a simple band-mass model is proposed to estimate the system’s separation shock. The differences between the model and experimental results are discussed. Radial and axial, but not tangential, separation shocks were estimated well by this method.

  18. Structural Mass Spectrometry: Rapid Methods for Separation and Analysis of Peptide Natural Products

    PubMed Central

    Goodwin, Cody R.; Fenn, Larissa S.; Derewacz, Dagmara K.; Bachmann, Brian O.; McLean, John A.

    2012-01-01

    A significant challenge in natural product discovery is the initial discrimination of discrete secondary metabolites alongside functionally similar primary metabolic cellular components within complex biological samples. A property that has yet to be fully exploited for natural product identification and characterization is the gas phase collision cross section, or, more generally, the mobility-mass correlation. Peptide natural products possess many of the properties that distinguish natural products as they are frequently characterized by a high degree of intramolecular bonding, and possess extended and compact conformations among other structural modifications. This report describes a rapid structural mass spectrometry technique based on ion mobility-mass spectrometry for the comparison of peptide natural products to their primary metabolic congeners using mobility-mass correlation. This property is empirically determined using ion mobility-mass spectrometry, applied to the analysis of linear versus modified peptides, and used to discriminate peptide natural products in a crude microbial extract. Complementary computational approaches are utilized to understand the structural basis for the separation of primary metabolism derived linear peptides from secondary metabolite cyclic and modified cyclic species. These findings provide a platform for enhancing the identification of secondary metabolic peptides with distinct mobility-mass ratios within complex biological samples. PMID:22216918

  19. Fast liquid chromatography separation and multiple-reaction monitoring mass spectrometric detection of neurotransmitters.

    PubMed

    Hammad, Loubna A; Neely, Matthew; Bridge, Bob; Mechref, Yehia

    2009-07-01

    We describe here the fast LC-MS/MS separation of a mixture of neurotransmitters consisting of dopamine, epinephrine, norepinephrine, 3,4-dihydroxybenzylamine (DHBA), salsolinol, serotonin, and gamma-aminobutyric acid (GABA). The new UltiMate 3000 Rapid Separation system (RSLC) was successfully coupled to the 4000 QTRAP mass spectrometer operating in multiple-reaction monitoring (MRM) mode. The separation was attained using a 100 mm length, 2.2 microm particle size Acclaim column at a flow rate of 0.5 mL/min. The column back pressure was 350 bar, while the total run time including column re-equilibration was 5.2 min. The peak resolution was minimally affected by the fast separation. The RSLC-MRM separation was found to have a precision range based on peak area for 50 replicate runs of 2-5% CV for all analytes, and the reproducibility of the retention time for all analytes was found to range from 0-2% CV. The described method represents an almost seven times shorter analysis time of neurotransmitters using LC/MRM which is very useful in screening large quantities of biological samples for various neurotransmitters. PMID:19569096

  20. Separation of catechin epimers by complexation using ion mobility mass spectrometry.

    PubMed

    Troć, Anna; Zimnicka, Magdalena; Danikiewicz, Witold

    2015-03-01

    Ion mobility coupled with mass spectrometry provides a fast and repeatable method to separate catechin epimers by previous complexation with selected chiral modifiers and transition metals. Several combinations with chiral ligands such as D- and L-amino acids and/or additional metal cations, chiral crown ethers, tartaric acid and heptakis(2,6-di-O-methyl)-β-cyclodextrin were screened for their ability to affect the separation efficiency. The clusters having the form of [2M + D-amino acid + Cu(2+) - 3H](-) (M stands for (-)-epicatechin or (+)-catechin) showed improvement in stereodifferentiation between two epimeric catechins in comparison to the analysis of pure epimers, where no separation was observed or the separation was hampered by the formation of mixed dimer complexes. Among various examined D-amino acids only those possessing hydrophobic side chains induced the improvement of separation efficiency. The best peak-to-peak resolution (Rp-p) was determined to be 0.71 for [2M + D-Leucine + Cu(2+) - 3H](-) clusters. PMID:25800190

  1. Spallation recoil and age of presolar grains in meteorites

    NASA Astrophysics Data System (ADS)

    Ott, U.; Begemann, F.

    2000-01-01

    We have determined the recoil losses from silicon carbide grain size fractions of spallation neon produced by irradiation with 1.6 GeV protons. During the irradiation the SiC grains were dispersed in paraffin wax in order to avoid re-implantation into neighboring grains. Analysis for spallogenic 21Ne of grain size separates in the size range 0.3 μm to 6 μm and comparison with the 22Na activity of the SiC+paraffin mixture indicates an effective recoil range of 2-3 μm with no apparent effect from acid treatments such as routinely used in the isolation of meteoritic SiC grains. Our results indicate that the majority of presolar SiC grains in primitive meteorites, which are ~μm-sized, will have lost essentially all spallogenic Ne produced by cosmic ray interaction in the interstellar medium. This argues against the validity of previously published presolar ages of Murchison SiC (~10 to ~130 Ma; increasing with grain size; Lewis et al., 1994), where recoil losses had been based on calculated recoil energies. It is argued that the observed variations in meteoritic SiC grain size fractions of 21Ne/22Ne ratios are more likely due to the effects of nucleosynthesis in the He burning shell of the parent AGB stars which imposes new boundary conditions on nuclear parameters and stellar models. It is suggested that spallation-Xe produced on the abundant Ba and REE in presolar SiC, rather than spallogenic Ne, may be a promising approach to the presolar age problem. There is a hint in the currently available Xe data (Lewis et al., 1994) that the large (>1 μm) grains may be younger than the smaller (<1 μm) ones.

  2. Advanced nanoscale separations and mass spectrometry for sensitive high-throughput proteomics

    SciTech Connect

    Shen, Yufeng; Smith, Richard D.

    2005-06-01

    We review recent development in separations and mass spectrometric instrumentation for sensitive and high-throughput proteomic analyses. These efforts have been primarily focused on the development of high-efficiency (separation peak capacity of ~103) nanoscale liquid chromatography (nanoLC; e.g., flow rates extending down to ~20 nL/min at optimal separation linear velocities through narrow packed capillaries) in combination with advanced mass spectrometry (MS), including high sensitivity and high resolution Fourier transform ion cyclotron resonance (FTICR) MS. This technology enables MS analysis of low nanogram-level proteomic samples (i.e., nanoscale proteomics) with individual protein identification sensitivity at the low zeptomole-level. The resultant protein measurement dynamic range can reach 106 for nanogram-sized proteomic samples, while more abundant proteins can be detected from complex sub-picogram size proteome samples. The average proteome identification throughput using MS/MS is >200 proteins/h for a ~3 h analysis. These qualities provide the foundation for proteomics studies of single or small populations of cells. The instrumental robustness required for automation and providing high quality routine performance nanoscale proteomic analyses is also discussed.

  3. Integrated microfluidic device for automated single cell analysis using electrophoretic separation and electrospray ionization mass spectrometry.

    PubMed

    Mellors, J Scott; Jorabchi, Kaveh; Smith, Lloyd M; Ramsey, J Michael

    2010-02-01

    A microfabricated fluidic device was developed for the automated real-time analysis of individual cells using capillary electrophoresis (CE) and electrospray ionization-mass spectrometry (ESI-MS). The microfluidic structure incorporates a means for rapid lysis of single cells within a free solution electrophoresis channel, where cellular constituents were separated, and an integrated electrospray emitter for ionization of separated components. The eluent was characterized using mass spectrometry. Human erythrocytes were used as a model system for this study. In this monolithically integrated device, cell lysis occurs at a channel intersection using a combination of rapid buffer exchange and an increase in electric field strength. An electroosmotic pump is incorporated at the end of the electrophoretic separation channel to direct eluent to the integrated electrospray emitter. The dissociated heme group and the alpha and beta subunits of hemoglobin from individual erythrocytes were detected as cells continuously flowed through the device. The average analysis throughput was approximately 12 cells per minute, demonstrating the potential of this method for high-throughput single cell analysis. PMID:20058879

  4. Integrated Microfluidic Device for Automated Single Cell Analysis using Electrophoretic Separation and Electrospray Ionization Mass Spectrometry

    PubMed Central

    Mellors, J. Scott; Jorabchi, Kaveh; Smith, Lloyd M.; Ramsey, J. Michael

    2010-01-01

    A microfabricated fluidic device was developed for the automated real-time analysis of individual cells using capillary electrophoresis (CE) and electrospray ionization-mass spectrometry (ESI-MS). The microfluidic structure incorporates a means for rapid lysis of single cells within a free solution electrophoresis channel where cellular constituents were separated and an integrated electrospray emitter for ionization of separated components. The eluent was characterized using mass spectrometry. Human erythrocytes were used as a model system for this study. In this monolithically integrated device, cell lysis occurs at a channel intersection using a combination of rapid buffer exchange and an increase in electric field strength. An electroosmotic pump is incorporated at the end of the electrophoretic separation channel to direct eluent to the integrated electrospray emitter. The dissociated heme group and the α and β subunits of hemoglobin from individual erythrocytes were detected as cells continuously flowed through the device. The average analysis throughput was approximately 12 cells per minute demonstrating the potential of this method for high-throughput single cell analysis. PMID:20058879

  5. Hidden in Starlight: A Search for Widely Separated Substellar-Mass Companions

    NASA Astrophysics Data System (ADS)

    Hulsebus, Alan; Marengo, Massimo; Carson, Joseph; Stapelfeldt, Karl R.

    2014-06-01

    Relatively few widely separated substellar-mass companions of planetary systems are known. These companions can alter the dynamics of planets through Kozai-mechanism-style secular perturbations, and may be a cause of the high mean eccentricity of exoplanets. The orbital periods of such companions are expected to be of the order of tens to thousands of years, making them undetectable by time-domain observations such as transit- and radial velocity searches. We have conducted a Spitzer/Infrared Array Camera (IRAC) 3.6 and 4.5 µm imaging search for widely separated substellar-mass companions with projected separation between 5 to 40 arcsec from their parent star. The 36 stars in my sample range from 4 to 15 pc from the sun, giving a typical sensitivity of 10 MJ for objects with an orbital radius in the range of 50 to 300 au. This search required advanced PSF-subtraction techniques in order to minimize the inner working angle and increase sensitivity. In this talk I present the results of this search and discuss the data analysis methods we developed for it.

  6. Diffusion mass transfer of KOH through Ni/Zn battery membrane separators

    NASA Astrophysics Data System (ADS)

    Poa, D. S.; Cook, G. M.; Yao, N. P.

    1983-01-01

    Three elements that influence KOH electrolyte diffusion fluxes through nickel/zinc battery separators are discussed: (1) concentration gradient; (2) temperature dependence; and (3) ordering of multilayer membranes. The KOH diffusion fluxes through three different Ni/Zn battery separators (193 PUDO cellophane, Celgard 3401 and 3501, and Permion P-2291 40/30) increase linearly with an increasing KOH concentration gradient from 10 to 40 wt%. The flux approaches a constant value as the concentration gradient is further increased from 45 to 60 wt%. This increase in diffusion mass transfer resistance, in the 45 to 60 wt% KOH concentration range, was analyzed by the modified Wilson plots and found to be related to an increase in the phase boundary resistance. It is shown that the temperature dependences of the KOH diffusion fluxes through these three separators are not the same and they do not always explicitly follow liquid phase diffusion theory. In the case of two layer composite membrane separators, in which one layer bears fixed negative charges and the other layer is an ideal Fickian membrane the KOH diffusion flux is higher when the charge bearing layer faces the concentrated side of the diffusion cell.

  7. Diffusion mass transfer of KOH through Ni/Zn battery membrane separators

    SciTech Connect

    Poa, D.S.; Cook, G.M.; Yao, N.P.

    1983-01-01

    This report discusses three elements that influence KOH electrolyte diffusion fluxes through nickel/zinc battery separators: concentration gradient, temperature dependence, and ordering of multilayer membranes. The KOH diffusion fluxes through three different Ni/Zn battery separators (193 PUDO cellophane, Celgard 3401 and 3501, and Permion P-2291 40/30) are found to increase linearly with an increasing KOH concentration gradient from 10 to 40 wt% (the dilute side of the diffusion cell was filled with distilled water). Typically, the flux approaches a constant value as the concentration gradient is further increased from 45 to 60 wt%. This increase in diffusion mass transfer resistance, in the 45 to 60 wt% KOH concentration range, was analyzed by the method of modified Wilson plots and found to be related to an increase in the phase boundary resistance. It was also shown that the temperature dependences of the KOH diffusion fluxes through these three separators are not the same. Furthermore, they do not always explicitly follow liquid phase diffusion theory. In the case of two-layer composite membrance separators, in which one layer bears fixed negative charges and the other layer is an ideal Fickian membrane (simple porous structure), the KOH diffusion flux is higher when the charge-bearing layer faces the concentrated side of the diffusion cell.

  8. Improving sensitivity for microchip electrophoresis interfaced with inductively coupled plasma mass spectrometry using parallel multichannel separation.

    PubMed

    Cheng, Heyong; Liu, Jinhua; Xu, Zigang; Wang, Yuanchao; Ye, Meiying

    2016-08-26

    We reported sensitivity enhancement using multichannel parallel separation for microchip electrophoresis hyphenated with inductively coupled plasma mass spectrometry (MCE-ICP-MS) in this study. By using 2-20 array lanes for parallel separation, the sensitivity of the MCE-ICP-MS system was proportionally improved by 2-20 folds. No significantly adverse effect of parallel separation on column efficiency and resolution was observed. Rapid separation of Hg(2+) and methylmercuric (MeHg) ion within 36s under an electric field of 800Vcm(-1) was achieved in the 2-cm twenty-channels with a background electrolyte of 5mmolL(-1) borate buffer (pH 9.2). Detection limits of Hg(2+) and MeHg by the proposed system were decreased to 6.8-7.1ngL(-1). Good agreement between determined values and certified values of a certified reference fish was obtained with recoveries ranged between 94-98%. All results prove its advantages including high sensitivity, high efficiency and low operation cost, which are beneficial to routine analysis of metal speciation in environmental, biological and food fields. PMID:27488720

  9. Revealing compressed stops using high-momentum recoils

    NASA Astrophysics Data System (ADS)

    Macaluso, Sebastian; Park, Michael; Shih, David; Tweedie, Brock

    2016-03-01

    Searches for supersymmetric top quarks at the LHC have been making great progress in pushing sensitivity out to higher mass, but are famously plagued by gaps in coverage around lower-mass regions where the decay phase space is closing off. Within the common stop-NLSP/neutralino-LSP simplified model, the line in the mass plane where there is just enough phase space to produce an on-shell top quark remains almost completely unconstrained. Here, we show that is possible to define searches capable of probing a large patch of this difficult region, with S/B ˜ 1 and significances often well beyond 5 σ. The basic strategy is to leverage the large energy gain of LHC Run 2, leading to a sizable population of stop pair events recoiling against a hard jet. The recoil not only re-establishes a [InlineMediaObject not available: see fulltext.] signature, but also leads to a distinctive anti-correlation between the [InlineMediaObject not available: see fulltext.] and the recoil jet transverse vectors when the stops decay all-hadronically. Accounting for jet combinatorics, backgrounds, and imperfections in [InlineMediaObject not available: see fulltext.] measurements, we estimate that Run 2 will already start to close the gap in exclusion sensitivity with the first few 10s of fb-1. By 300 fb-1, exclusion sensitivity may extend from stop masses of 550 GeV on the high side down to below 200 GeV on the low side, approaching the "stealth" point at {m}_{overline{t}}={m}_t and potentially overlapping with limits from toverline{t} cross section and spin correlation measurements.

  10. Evaluation of injection methods for fast, high peak capacity separations with low thermal mass gas chromatography.

    PubMed

    Fitz, Brian D; Mannion, Brandyn C; To, Khang; Hoac, Trinh; Synovec, Robert E

    2015-05-01

    Low thermal mass gas chromatography (LTM-GC) was evaluated for rapid, high peak capacity separations with three injection methods: liquid, headspace solid phase micro-extraction (HS-SPME), and direct vapor. An Agilent LTM equipped with a short microbore capillary column was operated at a column heating rate of 250 °C/min to produce a 60s separation. Two sets of experiments were conducted in parallel to characterize the instrumental platform. First, the three injection methods were performed in conjunction with in-house built high-speed cryo-focusing injection (HSCFI) to cryogenically trap and re-inject the analytes onto the LTM-GC column in a narrower band. Next, the three injection methods were performed natively with LTM-GC. Using HSCFI, the peak capacity of a separation of 50 nl of a 73 component liquid test mixture was 270, which was 23% higher than without HSCFI. Similar peak capacity gains were obtained when using the HSCFI with HS-SPME (25%), and even greater with vapor injection (56%). For the 100 μl vapor sample injected without HSCFI, the preconcentration factor, defined as the ratio of the maximum concentration of the detected analyte peak relative to the analyte concentration injected with the syringe, was determined to be 11 for the earliest eluting peak (most volatile analyte). In contrast, the preconcentration factor for the earliest eluting peak using HSCFI was 103. Therefore, LTM-GC is demonstrated to natively provide in situ analyte trapping, although not to as great an extent as with HSCFI. We also report the use of LTM-GC applied with time-of-flight mass spectrometry (TOFMS) detection for rapid, high peak capacity separations from SPME sampled banana peel headspace. PMID:25814332

  11. Base flow separation: A comparison of analytical and mass balance methods

    NASA Astrophysics Data System (ADS)

    Lott, Darline A.; Stewart, Mark T.

    2016-04-01

    Base flow is the ground water contribution to stream flow. Many activities, such as water resource management, calibrating hydrological and climate models, and studies of basin hydrology, require good estimates of base flow. The base flow component of stream flow is usually determined by separating a stream hydrograph into two components, base flow and runoff. Analytical methods, mathematical functions or algorithms used to calculate base flow directly from discharge, are the most widely used base flow separation methods and are often used without calibration to basin or gage-specific parameters other than basin area. In this study, six analytical methods are compared to a mass balance method, the conductivity mass-balance (CMB) method. The base flow index (BFI) values for 35 stream gages are obtained from each of the seven methods with each gage having at least two consecutive years of specific conductance data and 30 years of continuous discharge data. BFI is cumulative base flow divided by cumulative total discharge over the period of record of analysis. The BFI value is dimensionless, and always varies from 0 to 1. Areas of basins used in this study range from 27 km2 to 68,117 km2. BFI was first determined for the uncalibrated analytical methods. The parameters of each analytical method were then calibrated to produce BFI values as close to the CMB derived BFI values as possible. One of the methods, the power function (aQb + cQ) method, is inherently calibrated and was not recalibrated. The uncalibrated analytical methods have an average correlation coefficient of 0.43 when compared to CMB-derived values, and an average correlation coefficient of 0.93 when calibrated with the CMB method. Once calibrated, the analytical methods can closely reproduce the base flow values of a mass balance method. Therefore, it is recommended that analytical methods be calibrated against tracer or mass balance methods.

  12. Extension of the two-dimensional mass channel cluster plot method to fast separations utilizing low thermal mass gas chromatography with time-of-flight mass spectrometry.

    PubMed

    Fitz, Brian D; Synovec, Robert E

    2016-03-24

    Implementation of a data reduction and visualization method for use with high-speed gas chromatography and time-of-flight mass spectrometry (GC-TOFMS) is reported. The method, called the "2D m/z cluster method" facilitates analyte detection, deconvolution, and identification, by accurately measuring peak widths and retention times using a fast TOFMS sampling frequency (500 Hz). Characteristics and requirements for high speed GC are taken into consideration: fast separations with narrow peak widths and high peak capacity, rapid data collection rate, and effective peak deconvolution. Transitioning from standard GC (10-60+ minute separations) to fast GC (1-10 min separations) required consideration of how to properly analyze the data. This report validates use of the 2D m/z cluster method with newly developed GC technology that produces ultra-fast separations (∼1 min) with narrow analyte peak widths. Low thermal mass gas chromatography (LTM-GC) operated at a heating rate of 250 °C/min coupled to a LECO Pegasus III TOFMS analyzed a 115 component test mixture in 120 s with peak widths-at-base, wb (4σ), of 350 ms (average) to produce a separation with a high peak capacity, nc ∼ 340 (at unit resolution Rs = 1). The 2D m/z cluster method is shown to separate overlapped analytes to a limiting Rs ∼ 0.03, so the effective peak capacity was increased nearly 30-fold to nc ∼10,000 in the 120 s separation. The method, when coupled with LTM-GC-TOFMS, is demonstrated to provide unambiguous peak rank (i.e. the number of analytes per overlapped peak in the total ion current (TIC)), by visualizing locations of pure and chromatographically overlapped m/z. Hence, peak deconvolution and identification using MCR-ALS (multivariate curve resolution - alternating least squares) is demonstrated. PMID:26945000

  13. Toward a Human Blood Serum Proteome: Analysis by Multidimensional Separation Coupled with Mass Spectrometry

    SciTech Connect

    Adkins, Joshua N.); Varnum, Susan M.); Auberry, Kenneth J.); Moore, Ronald J.); Angell, Nicolas; Smith, Richard D.); Springer, David L.); Pounds, Joel G.)

    2002-12-01

    Blood serum is a complex bodily fluid that contains proteins ranging in concentration over at least nine orders of magnitude. Using a combination of powerful mass spectrometry technologies with improvements in sample preparation, we have performed a proteomic analysis with sub-mL quantities of serum, and increased the measurable concentration range for proteins in blood serum beyond previous reports. We have detected 490 proteins in serum by online reversed-phase microcapillary liquid chromatography coupled with ion trap mass spectrometry. To perform this analysis, immunoglobulins were removed from serum using protein A/G, and the remaining proteins were digested with trypsin. Resulting peptides were separated by strong-cation exchange chromatography into distinct fractions prior to analysis. This separation resulted in an increase in the number of proteins detected in an individual serum sample by 3 to 5 fold. With this increase in the number of proteins identified we have detected some lower abundance serum proteins (ng/mL range) including human growth hormone, interleukin-12, and prostate-specific antigen. We also used SEQUEST to compare different protein databases with and without filtering. This comparison is plotted to allow for a quick visual assessment of different databases, as a subjective measure of quality. With this study, we have performed the most extensive analysis of serum proteins to date and laid the foundation for future refinements in the identification of novel protein biomarkers of disease.

  14. Mass spectrometric characterization of gentamicin components separated by the new European Pharmacopoeia method.

    PubMed

    Li, B; Van Schepdael, A; Hoogmartens, J; Adams, E

    2011-04-28

    Liquid chromatography combined with pulsed electrochemical detection (LC-PED) is the method of choice in the European Pharmacopoeia for the determination of gentamicin and its related substances. A recently approved improved LC-PED method, with a reversed-phase C(18) column and a mobile phase consisting of trifluoroacetic acid (TFA), pentafluoropropionic acid (PFPA), sodium hydroxide and acetonitrile, showed better separation and more sensitive detection of the gentamicin components than the previous method using a polymer column. More unknown peaks can be separated from the main components and from each other. As the LC-PED method cannot be directly coupled to a mass spectrometer (MS), the unknown substances were collected after the LC column, desalted and analyzed by MS. The structures of the unknown compounds were deduced based on comparison of their fragmentation patterns with those of reference substances investigated by MS(n) experiments using an electrospray ion trap mass spectrometer. A comparison was also made with an already previously published LC-MS method using a volatile mobile phase. PMID:21316176

  15. Ion Mobility Separation of Isomeric Carbohydrate Precursor Ions and Acquisition of their Independent Tandem Mass Spectra

    PubMed Central

    Zhu, Maolei; Bendiak, Brad; Clowers, Brian; Hill, Herbert H.

    2010-01-01

    The rapid separation of isomeric precursor ions of oligosaccharides prior to their analysis by MSn was demonstrated using an ambient pressure ion mobility spectrometer (IMS) interfaced with a quadrupole ion trap. Separations were not limited to specific types of isomers; representative isomers differing solely in the stereochemistry of sugars, in their anomeric configurations, and in their overall branching patterns and linkage positions could be resolved in the millisecond time frame. Physical separation of precursor ions permitted independent mass spectra of individual oligosaccharide isomers to be acquired to at least MS3, the number of stages of dissociation limited only practically by the abundance of specific product ions. IMS-MSn analysis was particularly valuable in the evaluation of isomeric oligosaccharides that yielded identical sets of product ions in MS/MS experiments, revealing pairs of isomers that would otherwise not be known to be present in a mixture if evaluated solely by MS dissociation methods alone. A practical example of IMS-MSn analysis of a set of isomers included within a single HPLC fraction of oligosaccharides released from bovine submaxillary mucin is described. PMID:19562326

  16. Fast separation of triterpenoid saponins using supercritical fluid chromatography coupled with single quadrupole mass spectrometry.

    PubMed

    Huang, Yang; Zhang, Tingting; Zhou, Haibo; Feng, Ying; Fan, Chunlin; Chen, Weijia; Crommen, Jacques; Jiang, Zhengjin

    2016-03-20

    Triterpenoid saponins (TSs) are the most important components of some traditional Chinese medicines (TCMs) and have exhibited valuable pharmacological properties. In this study, a rapid and efficient method was developed for the separation of kudinosides, stauntosides and ginsenosides using supercritical fluid chromatography coupled with single quadrupole mass spectrometry (SFC-MS). The separation conditions for the selected TSs were carefully optimized after the initial screening of eight stationary phases. The best compromise for all compounds in terms of chromatographic performance and MS sensitivity was obtained when water (5-10%) and formic acid (0.05%) were added to the supercritical carbon dioxide/MeOH mobile phase. Beside the composition of the mobile phase, the nature of the make-up solvent for interfacing SFC with MS was also evaluated. Compared to reversed phase liquid chromatography, the SFC approach showed higher resolution and shorter running time. The developed SFC-MS methods were successfully applied to the separation and identification of TSs present in Ilex latifolia Thunb., Panax quinquefolius L. and Panax ginseng C.A. Meyer. These results suggest that this SFC-MS approach could be employed as a useful tool for the quality assessment of natural products containing TSs as active components. PMID:26773536

  17. [Separation of tannins in Rhubarb and its analysis by high performance liquid chromatography-mass spectrometry].

    PubMed

    Ding, Mingyu; Ni, Weiwei

    2004-11-01

    In order to investigate the pharmaceutical actions of rhubarb, a method for extracting, separating and analyzing the tannin components in rhubarb was studied. At first, a procedure for the group separation of tannins from the water-ethanol extract of rhubarb was established based on the formation of tannins-caffein precipitation. Then, a high performance liquid chromatographic (HPLC) method for the analysis of tannins in rhubarb was developed. This HPLC method is based on a reversed-phase C18 column and polar mobile-phase such as water and methanol with gradient elution, and the tannins can be well separated. Finally, the identification of the tannin components in rhubarb was carried out by high performance liquid chromatography-mass spectrometry (HPLC-MS). The structures of the main tannin components (gallic acid, catechin, the dimer, trimer, tetramer and pentamer of catechin) in rhubarb are suggested. The fragmentation laws of the tannin components are summarized. In comparing with previous methods, it is simple and without the interference of co-existed compounds. PMID:15807111

  18. Molecular Dynamics Simulation of Energetic Uranium Recoil Damage in Zircon

    SciTech Connect

    Devanathan, Ram; Corrales, Louis R.; Weber, William J.; Chartier, Alain; Meis, Constantin

    2006-10-11

    Defect production and amorphization due to energetic uranium recoils in zircon (ZrSiO4), which is a promising ceramic nuclear waste form, is studied using molecular dynamics simulations with a partial charge model. An algorithm that distinguishes between undamaged crystal, crystalline defects and amorphous regions is used to develop a fundamental understanding of the primary damage state. The amorphous cascade core is separated from the surrounding crystal by a defect-rich region. Small, chemically inhomogeneous amorphous clusters are also produced around the core. The amorphous regions consist of under-coordinated Zr and polymerized Si leading to amorphization and phase separation on a nanometer scale into Zr- and Si-rich regions. This separation could play an important role in the experimentally observed formation of nanoscale ZrO2 in ZrSiO4 irradiated at elevated temperatures.

  19. Separation and identification of oligomeric vinylmethoxysiloxanes by gradient elution chromatography coupled with electrospray ionization mass spectrometry.

    PubMed

    Jia, Guiying; Wan, Qian-Hong

    2015-05-22

    A high-performance liquid chromatography with online electrospray ionization mass spectrometry (HPLC-ESI-MS) has been used to separate and identify the reaction products resulting from controlled acid-catalyzed hydrolytic polycondensation of vinyltrimethoxysilane (VMS). The reaction products were prepared in the molar ratio of water to VMS (r1) ranging from 0.6 to 1.2, characterized by standard spectroscopic techniques, and subsequently analyzed by HPLC-UV absorbance detection and HPLC-ESI-MS. Linear vinylmethoxysiloxane oligomers with the number of repeat units (n) ranging from 3 to 11 are predominant species at the beginning of the reaction (for r1=0.6). Then they transform into monocyclic (for r1=1.0) and bicyclic (for r1=1.2) species with gradually increasing amount of water in the reaction mixture. The oligomer conversions suggest that structure growth of vinylmetoxysiloxanes proceeds by nonrandom cyclization reactions, which are favored over chain extension under the chosen reaction conditions. Direct ESI-MS, HPLC-ESI-MS and HPLC-UV were used to determine the molar mass distributions for the vinylmethoxysiloxane oligomers prepared in three different values of r1. The molar mass averages increase slightly with the amount of water in the reaction mixture and vary somewhat with the method used. Our results indicate that with the combined capability of separation, sensitivity and identification, HPLC-ESI-MS is especially useful to study highly complex silicon-based compounds with hyperbranched, caged or cubic structures as building blocks for hybrid materials. PMID:25890439

  20. Elastic recoil changes in early emphysema.

    PubMed Central

    Silvers, G W; Petty, T L; Stanford, R E

    1980-01-01

    An attempt was made to determine if emphysema and static lung recoil were related in a group of 65 excised human lungs. We studied 23 normal lungs, 24 lungs with an emphysema score of 5 or less, and 18 lungs with an emphysema score greater than 5. A comparison of the percentage of predicted elastic recoil revealed that both emphysema groups were significantly different from normal lungs. In addition, the total lung capacities were significantly different between the three groups. In the group with an emphysema score greater than 5 we found a linear negative correlation between the extent of emphysema and percent of predicted elastic recoil at 90% total lung capacity (r = -0.696, p < 0.01). We found a negative correlation between the percentage of predicted elastic recoil and the lung volume (r = -0.612, p < 0.01). We conclude that a significant loss of elastic recoil and a significant increase in total lung capacity occurs in the early stages of emphysema. PMID:7434309

  1. Americium and plutonium separation by extraction chromatography for determination by accelerator mass spectrometry.

    PubMed

    Kazi, Zakir H; Cornett, Jack R; Zhao, Xaiolei; Kieser, Liam

    2014-06-01

    A simple method was developed to separate Pu and Am using single column extraction chromatography employing N,N,N',N'-tetra-n-octyldiglycolamide (DGA) resin. Isotope dilution measurements of Am and Pu were performed using accelerator mass spectrometry (AMS) and alpha spectrometry. For maximum adsorption Pu was stabilized in the tetra valent oxidation state in 8M HNO3 with 0.05 M NaNO2 before loading the sample onto the resin. Am(III) was adsorbed also onto the resin from concentrated HNO3, and desorbed with 0.1 M HCl while keeping the Pu adsorbed. The on-column reduction of Pu(IV) to Pu(III) with 0.02 M TiCl3 facilitated the complete desorption of Pu. Interferences (e.g. Ca(2+), Fe(3+)) were washed off from the resin bed with excess HNO3. Using NdF3, micro-precipitates of the separated isotopes were prepared for analysis by both AMS and alpha spectrometry. The recovery was 97.7±5.3% and 95.5±4.6% for (241)Am and (242)Pu respectively in reagents without a matrix. The recoveries of the same isotopes were 99.1±6.0 and 96.8±5.3% respectively in garden soil. The robustness of the method was validated using certified reference materials (IAEA 384 and IAEA 385). The measurements agree with the certified values over a range of about 1-100 Bq kg(-1). The single column separation of Pu and Am saves reagents, separation time, and cost. PMID:24856406

  2. COMMERCIAL APPLICATION OF PLASMA MASS SEPARATION IN THE ARCHIMEDES FILTER PLANT

    SciTech Connect

    Ahlfeld, C.E.; Gilleland, J.G.; Wagoner, J.D.

    2003-02-27

    This paper describes the commercial application of an innovative plasma mass separator called the Archimedes Filter to a pre-treatment plant that can be integrated into the U.S. Department of Energy (DOE) Hanford and Savannah River Sites to significantly enhance the treatment of radioactive high-level waste. The output of the Archimedes Filter is completely compatible with existing waste immobilization processes such as vitrification and requires no new waste form to be developed. A full-geometric-scale Demonstration Filter Unit (DEMO) has been constructed and is undergoing initial testing at the Archimedes Technology Group Development Facilities in San Diego. Some of the technology and engineering development is being performed by other organizations in collaboration with Archimedes. The Commissariat a l'Energie Atomique (CEA) is developing the plasma calcination technology and all of the associated systems for AFP feed preparation. Two Russian institutes are involved in the development of the ICP torch and injector system. The Remote System Group (UT-Battelle) at ORNL is developing the remote maintenance system for the filter units. Conceptual design of the Archimedes Filter Plant (AFP) is being developed concurrently with the DEMO testing program. The AFP mission is to significantly reduce the cost and accelerate the rate of vitrification of high-level waste by separating low activity waste from the sludge removed from underground storage tanks. Mass separation is accomplished by vaporizing the sludge feed and injecting it into a partially ionized, neutral plasma. In a single pass, heavy ions are deposited near the center of the filter and light mass ions are transported by the plasma to the ends of the cylindrically-shaped vacuum vessel. Responding to the DOE programs for cost reduction and cleanup acceleration, the AFP Project is planned on an expeditious schedule that executes all phases of the project with private sector funding. The initial AFP

  3. Contribution of mass density heterogeneities to the quasigeoid-to-geoid separation

    NASA Astrophysics Data System (ADS)

    Tenzer, Robert; Hirt, Christian; Novák, Pavel; Pitoňák, Martin; Šprlák, Michal

    2016-01-01

    The geoid-to-quasigeoid separation is often computed only approximately as a function of the simple planar Bouguer gravity anomaly and the height of the computation point while disregarding the contributions of terrain geometry and anomalous topographic density as well as the sub-geoid masses. In this study we demonstrate that these contributions are significant and, therefore, should be taken into consideration when investigating the relation between the normal and orthometric heights particularly in the mountainous, polar and geologically complex regions. These contributions are evaluated by applying the spectral expressions for gravimetric forward modelling and using the EIGEN-6C4 gravity model, the Earth2014 datasets of terrain, ice thickness and inland bathymetry and the CRUST1.0 sediment and (consolidated) crustal density data. Since the global crustal density models currently available (e.g. CRUST1.0) have a limited accuracy and resolution, the comparison of individual density contributions is—for consistency—realized with a limited spectral resolution up to a spherical harmonic degree 360 (or 180). The results reveal that the topographic contribution globally varies between -0.33 and 0.57 m, with maxima in Himalaya and Tibet. The contribution of ice considerably modifies the geoid-to-quasigeoid separation over large parts of Antarctica and Greenland, where it reaches ˜ 0.2 m. The contributions of sediments and bedrock are less pronounced, with the values typically varying only within a few centimetres. These results, however, have still possibly large uncertainties due to the lack of information on the actual sediment and bedrock density. The contribution of lakes is mostly negligible; its maxima over the Laurentian Great Lakes and the Baikal Lake reach only several millimetres. The contribution of the sub-geoid masses is significant. It is everywhere negative and reaches extreme values of -4.43 m. According to our estimates, the geoid

  4. A Mass Spectrometry Study of Isotope Separation in the Laser Plume

    NASA Astrophysics Data System (ADS)

    Suen, Timothy Wu

    Accurate quantification of isotope ratios is critical for both preventing the development of illicit weapons programs in nuclear safeguards and identifying the source of smuggled material in nuclear forensics. While isotope analysis has traditionally been performed by mass spectrometry, the need for in situ measurements has prompted the development of optical techniques, such as laser-induced breakdown spectroscopy (LIBS) and laser ablation molecular isotopic spectrometry (LAMIS). These optical measurements rely on laser ablation for direct solid sampling, but several past studies have suggested that the distribution of isotopes in the ablation plume is not uniform. This study seeks to characterize isotope separation in the laser plume through the use of orthogonal-acceleration time-of-flight mass spectrometry. A silver foil was ablated with a Nd:YAG at 355 nm at an energy of 50 muJ with a spot size of 71 mum, for a fluence of 1.3 J/cm2 and an irradiance of 250 MW/cm2. Flat-plate repellers were used to sample the plume, and a temporal profile of the ions was obtained by varying the time delay on the high-voltage pulse. A spatial profile along the axis of the plume was generated by changing the position of the sample, which yielded snapshots of the isotopic composition with time. In addition, the reflectron time-of-flight system was used as an energy filter in conjunction with the repellers to sample slices of the laser plasma orthogonal to the plume axis. Mass spectrometry of the plume revealed a fast ion distribution and a slow ion distribution. Measurements taken across the entire plume showed the fast 109Ag ions slightly ahead in both space and time, causing the 107Ag fraction to drop to 0.34 at 3 mus, 4 mm from the sample surface. Although measurements centered on the near side of the plume did not show isotope separation, the slow ions on the far side of the plume included much more 109Ag than 107Ag. In addition to examining the isotope content of the ablation

  5. Identifying Gel-Separated Proteins Using In-Gel Digestion, Mass Spectrometry, and Database Searching: Consider the Chemistry

    ERIC Educational Resources Information Center

    Albright, Jessica C.; Dassenko, David J.; Mohamed, Essa A.; Beussman, Douglas J.

    2009-01-01

    Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry is an important bioanalytical technique in drug discovery, proteomics, and research at the biology-chemistry interface. This is an especially powerful tool when combined with gel separation of proteins and database mining using the mass spectral data. Currently, few hands-on…

  6. Advanced Multidimensional Separations in Mass Spectrometry: Navigating the Big Data Deluge.

    PubMed

    May, Jody C; McLean, John A

    2016-06-12

    Hybrid analytical instrumentation constructed around mass spectrometry (MS) is becoming the preferred technique for addressing many grand challenges in science and medicine. From the omics sciences to drug discovery and synthetic biology, multidimensional separations based on MS provide the high peak capacity and high measurement throughput necessary to obtain large-scale measurements used to infer systems-level information. In this article, we describe multidimensional MS configurations as technologies that are big data drivers and review some new and emerging strategies for mining information from large-scale datasets. We discuss the information content that can be obtained from individual dimensions, as well as the unique information that can be derived by comparing different levels of data. Finally, we summarize some emerging data visualization strategies that seek to make highly dimensional datasets both accessible and comprehensible. PMID:27306312

  7. Preparation of high-purity Cu films by non-mass separated ion beam deposition

    NASA Astrophysics Data System (ADS)

    Lim, J.-W.; Mimura, K.; Miyake, K.; Yamashita, M.; Isshiki, M.

    2003-05-01

    Cu films were deposited on Si(1 0 0) substrates by applying a negative substrate bias voltage using non-mass separated ion beam deposition (IBD) method. By the SIMS results with Cs + ion beam, the Cu film deposited at VS=0 V was found to contain more impurities than the Cu film deposited at VS=-50 V. On the other hand, from the SIMS results with O 2+ ion beam, it was found that elements which are easy to be positive ions such as B, Mg, Na, Al, K, Ca and Fe seem to be increased slightly as compared to the those of the Cu film deposited at VS=0 V. As a result, higher-purity Cu film deposited at VS=-50 V could be obtained in comparison with the film deposited at VS=0 V. The purification effect of the Cu film deposited at VS=-50 V was described in details.

  8. Hollow fiber apparatus and use thereof for fluids separations and heat and mass transfers

    SciTech Connect

    Bikson, Benjamin; Etter, Stephen; Ching, Nathaniel

    2014-06-10

    A hollow fiber device includes a hollow fiber bundle, comprising a plurality of hollow fibers, a first tubesheet and a second tubesheet encapsulating respective distal ends of the hollow fiber bundle. The tubesheets have boreholes in fluid communication with bores of the hollow fibers. In at least one of the tubesheets, the boreholes are formed radially. The hollow fiber device can be utilized in heat exchange, in gas/gas, liquid/liquid and gas/liquid heat transfer, in combined heat and mass transfer and in fluid separation assemblies and processes. The design disclosed herein is light weight and compact and is particularly advantageous when the pressure of a first fluid introduced into the bores of hollow fibers is higher than the pressure on the shell side of the device.

  9. Advanced Multidimensional Separations in Mass Spectrometry: Navigating the Big Data Deluge

    NASA Astrophysics Data System (ADS)

    May, Jody C.; McLean, John A.

    2016-06-01

    Hybrid analytical instrumentation constructed around mass spectrometry (MS) is becoming the preferred technique for addressing many grand challenges in science and medicine. From the omics sciences to drug discovery and synthetic biology, multidimensional separations based on MS provide the high peak capacity and high measurement throughput necessary to obtain large-scale measurements used to infer systems-level information. In this article, we describe multidimensional MS configurations as technologies that are big data drivers and review some new and emerging strategies for mining information from large-scale datasets. We discuss the information content that can be obtained from individual dimensions, as well as the unique information that can be derived by comparing different levels of data. Finally, we summarize some emerging data visualization strategies that seek to make highly dimensional datasets both accessible and comprehensible.

  10. A new acceleration switch based on separated mass component and elastic component

    NASA Astrophysics Data System (ADS)

    Wu, Liping; Hu, Jun; Yang, Bo; Shao, Qing; Peng, Gang

    2010-10-01

    This paper presents a new linear inertial acceleration switch which senses inertial acceleration and gives a signal of switchpoint. It is an entire mechanical device has two particular characters: a simple structure and an environmental interference-free capability. The structure and work principle of the switch is introduced, then the design process to the spring is analyzed and simulated, and finally the rationality of this acceleration switch's design is given according to the sample's testing data. In this acceleration switch, the elastic component is a leaf spring, and the mass component is a standard steel ball. The spring and the ball are separated instead of rigidly connected, which make the whole structure is simple. When the switch is on the work direction the ball and the spring are interact, and the spring is on work; when the switch isn't on the work direction, the ball and the spring are separated; environmental external force is on the mass instead of on the spring. The spring is insusceptible on this condition. This particularity determines that the switch is highly environmental interference-free, and doesn't easily affected by environmental influence. Some parameters of the inertial switch are given as followings: (1) Overall dimension of the inertial switch is about 28mm×12mm×12mm (2) systemic precision of the inertial switch is 1.5%; (3) the inertial switch can endure 0.2g2/Hz stochastic vibration. It is suggested that this inertial switch can be applied in high consequence system.

  11. Separation and Analysis of Boron Isotope in High Plant by Thermal Ionization Mass Spectrometry

    PubMed Central

    Xu, Qingcai; Dong, Yuliang; Zhu, Huayu; Sun, Aide

    2015-01-01

    Knowledge of boron and its isotope in plants is useful to better understand the transposition and translocation of boron within plant, the geochemical behavior in the interface between soil and plant, and the biogeochemical cycle of boron. It is critical to develop a useful method to separate boron from the plant for the geochemical application of boron and its isotope. A method was developed for the extraction of boron in plant sample, whose isotope was determined by thermal ionization mass spectrometry. The results indicated that this method of dry ashing coupled with two-step ion-exchange chromatography is powerful for the separation of boron in plant sample with large amounts of organic matters completely. The ratios of boron isotope composition in those plant tissue samples ranged from −19.45‰ to +28.13‰ (total range: 47.58‰) with a mean value of 2.61 ± 11.76‰ SD. The stem and root isotopic compositions were lower than those in flower and leaf. The molecular mechanism of boron isotope may be responsible for the observed variation of boron isotopic composition and are considered as a useful tool for the better understanding of boron cycling process in the environment and for the signature of living systems. PMID:26819618

  12. Separation and characterization of oxidized isomeric lipid-peptide adducts by ion mobility mass spectrometry.

    PubMed

    Milic, Ivana; Kipping, Marc; Hoffmann, Ralf; Fedorova, Maria

    2015-12-01

    Phospholipids are major components of cell membranes and lipoprotein complexes. They are prone to oxidation by endogenous and exogenous reactive oxygen species yielding a large variety of modified lipids including small aliphatic and phospholipid bound aldehydes and ketones. These carbonyls are strong electrophiles that can modify proteins and, thereby, alter their structures and functions triggering various pathophysiological conditions. The analysis of lipid-protein adducts by liquid chromatography-MS is challenged by their mixed chemical nature (polar peptide and hydrophobic lipid), low abundance in biological samples, and formation of multiple isomers. Thus, we investigated traveling wave ion mobility mass spectrometry (TWIMS) to analyze lipid-peptide adducts generated by incubating model peptides corresponding to the amphipathic β1 sheet sequence of apolipoprotein B-100 with 1-palmitoyl-2-(oxo-nonanoyl)-sn-glycerophosphatidylcholine (PONPC). The complex mixture of peptides, lipids, and peptide-lipid adducts was separated by TWIMS, which was especially important for the identification of two mono-PONPC-peptide isomers containing Schiff bases at different lysine residues. Moreover, TWIMS separated structural conformers of one peptide-lipid adduct possessing most likely different orientations of the hydrophobic sn-1 fatty acyl residue and head group of PONPC, relative to the peptide backbone. PMID:26634972

  13. Separation and Analysis of Boron Isotope in High Plant by Thermal Ionization Mass Spectrometry.

    PubMed

    Xu, Qingcai; Dong, Yuliang; Zhu, Huayu; Sun, Aide

    2015-01-01

    Knowledge of boron and its isotope in plants is useful to better understand the transposition and translocation of boron within plant, the geochemical behavior in the interface between soil and plant, and the biogeochemical cycle of boron. It is critical to develop a useful method to separate boron from the plant for the geochemical application of boron and its isotope. A method was developed for the extraction of boron in plant sample, whose isotope was determined by thermal ionization mass spectrometry. The results indicated that this method of dry ashing coupled with two-step ion-exchange chromatography is powerful for the separation of boron in plant sample with large amounts of organic matters completely. The ratios of boron isotope composition in those plant tissue samples ranged from -19.45‰ to +28.13‰ (total range: 47.58‰) with a mean value of 2.61 ± 11.76‰ SD. The stem and root isotopic compositions were lower than those in flower and leaf. The molecular mechanism of boron isotope may be responsible for the observed variation of boron isotopic composition and are considered as a useful tool for the better understanding of boron cycling process in the environment and for the signature of living systems. PMID:26819618

  14. Proteomic profiling of intact proteins using WAX-RPLC 2-D separations and FTICR mass spectrometry

    SciTech Connect

    Sharma, Seema; Simpson, David C.; Tolic, Nikola; Jaitly, Navdeep; Mayampurath, Anoop M.; Smith, Richard D.; Pasa-Tolic, Liljiana

    2007-02-01

    We investigated the combination of weak anion exchange (WAX) fractionation and on-line reversed phase liquid chromatography (RPLC) separation using a 12 T FTICR mass spectrometer for the detection of intact proteins from a Shewanella oneidensis MR-1 cell lysate. 715 intact proteins were detected and the combined results from the WAX fractions and the unfractionated cell lysate were aligned using LC-MS features to facilitate protein abundance measurements. Protein identifications and post translational modifications were assigned for ~10% of the detected proteins by comparing intact protein mass measurements to proteins identified in peptide MS/MS analysis of an aliquot of the same fraction. Intact proteins were also detected for S. oneidensis lysates obtained from cells grown on 13C, 15N depleted media under aerobic and sub-oxic conditions. This work aimed at optimizing intact protein detection for profiling proteins at a level that incorporates their modification complement. The strategy can be readily applied for measuring differential protein abundances, and provides a platform for high-throughput selection of biologically relevant targets for further characterization.

  15. Many overlapping peptides for protein hydrogen exchange experiments by the fragment separation-mass spectrometry method.

    PubMed

    Mayne, Leland; Kan, Zhong-Yuan; Chetty, Palaniappan Sevugan; Ricciuti, Alec; Walters, Benjamin T; Englander, S Walter

    2011-11-01

    Measurement of the naturally occurring hydrogen exchange (HX) behavior of proteins can in principle provide highly resolved thermodynamic and kinetic information on protein structure, dynamics, and interactions. The HX fragment separation-mass spectrometry method (HX-MS) is able to measure hydrogen exchange in biologically important protein systems that are not accessible to NMR methods. In order to achieve high structural resolution in HX-MS experiments, it will be necessary to obtain many sequentially overlapping peptide fragments and be able to identify and analyze them efficiently and accurately by mass spectrometry. This paper describes operations which, when applied to four different proteins ranging in size from 140 to 908 residues, routinely provides hundreds of useful unique peptides, covering the entire protein length many times over. Coverage in terms of the average number of peptide fragments that span each amino acid exceeds 10. The ability to achieve these results required the integrated application of experimental methods that are described here and a computer analysis program, called ExMS, described in a following paper. PMID:21952777

  16. Separation Of Uranium And Plutonium Isotopes For Measurement By Multi Collector Inductively Coupled Plasma Mass Spectroscopy

    SciTech Connect

    Martinelli, R E; Hamilton, T F; Williams, R W; Kehl, S R

    2009-03-29

    Uranium (U) and plutonium (Pu) isotopes in coral soils, contaminated by nuclear weapons testing in the northern Marshall Islands, were isolated by ion-exchange chromatography and analyzed by mass spectrometry. The soil samples were spiked with {sup 233}U and {sup 242}Pu tracers, dissolved in minerals acids, and U and Pu isotopes isolated and purified on commercially available ion-exchange columns. The ion-exchange technique employed a TEVA{reg_sign} column coupled to a UTEVA{reg_sign} column. U and Pu isotope fractions were then further isolated using separate elution schemes, and the purified fractions containing U and Pu isotopes analyzed sequentially using multi-collector inductively coupled plasma mass spectrometer (MCICP-MS). High precision measurements of {sup 234}U/{sup 235}U, {sup 238}U/{sup 235}U, {sup 236}U/{sup 235}U, and {sup 240}Pu/{sup 239}Pu in soil samples were attained using the described methodology and instrumentation, and provide a basis for conducting more detailed assessments of the behavior and transfer of uranium and plutonium in the environment.

  17. Proton recoil scintillator neutron rem meter

    DOEpatents

    Olsher, Richard H.; Seagraves, David T.

    2003-01-01

    A neutron rem meter utilizing proton recoil and thermal neutron scintillators to provide neutron detection and dose measurement. In using both fast scintillators and a thermal neutron scintillator the meter provides a wide range of sensitivity, uniform directional response, and uniform dose response. The scintillators output light to a photomultiplier tube that produces an electrical signal to an external neutron counter.

  18. Imprints of recoiling massive black holes on the hot gas of early-type galaxies

    NASA Astrophysics Data System (ADS)

    Devecchi, B.; Rasia, E.; Dotti, M.; Volonteri, M.; Colpi, M.

    2009-04-01

    Anisotropic gravitational radiation from a coalescing black hole (BH) binary is known to impart recoil velocities of up to ~1000kms-1 to the remnant BH. In this context, we study the motion of a recoiling BH inside a galaxy modelled as a Hernquist sphere, and the signature that the hole imprints on the hot gas, using N-body/smoothed particle hydrodynamics simulations. Ejection of the BH results in a sudden expansion of the gas ending with the formation of a gaseous core, similarly to what is seen for the stars. A cometary tail of particles bound to the BH is initially released along its trail. As the BH moves on a return orbit, a nearly spherical swarm of hot gaseous particles forms at every apocentre: this feature can live up to ~108 years. If the recoil velocity exceeds the sound speed initially, the BH shocks the gas in the form of a Mach cone in density near each supersonic pericentric passage. We find that the X-ray fingerprint of a recoiling BH can be detected in Chandra X-ray maps out to a distance of Virgo. For exceptionally massive BHs, the Mach cone and the wakes can be observed out to a few hundred of milliparsec. The detection of the Mach cone is of twofold importance as it can be a probe of high-velocity recoils, and an assessment of the scatter of the MBH - Mbulge relation at large BH masses.

  19. Enriching and Separating Primary Copper Impurity from Pb-3 Mass Pct Cu Melt by Super-Gravity Technology

    NASA Astrophysics Data System (ADS)

    Yang, Yuhou; Song, Bo; Song, Gaoyang; Yang, Zhanbing; Xin, Wenbin

    2016-08-01

    In this study, super-gravity technology was introduced in the lead bullion-refining process to investigate the enriching and separating laws of copper impurity from Pb-3 mass pct Cu melt. With the gravity coefficient G = 700 at the cooling rate of ν = 5 K min-1, the entire copper phase gathers at the upper area of the sample, and it is hard to find any copper particles at the bottom area of the sample. The floatation movement of copper phase was greatly intensified by super gravity and the mass pct of copper in tailing lead is up to 8.631 pct, while that in the refined lead is only 0.113 pct. The refining rate of lead bullion reached up to 94.27 pct. Copper-phase impurity can be separated effectively from Pb-3 mass pct Cu melt by filtration method in super-gravity field, and the separation efficiency increased with the increasing gravity coefficient in the range of G ≥ 10. After filtration at 613 K (340 °C) with gravity coefficient G = 100 for 10 minutes, the refined lead, with just 0.157 mass pct copper impurity, was separated to the bottom of the crucible, and the copper dross containing only 23.56 mass pct residual lead was intercepted by the carbon fiber felt, leading to the separation efficiency up to 96.18 pct (meaning a great reduction in metal loss).

  20. Medium modifications with recoil polarization

    SciTech Connect

    Brand, J.F.J. van den; Ent, R.

    1994-04-01

    The authors show that the virtual Compton scattering process allows for a precise study of the off-shell electron-nucleon vertex. In a separable model, they show the sensitivity to new unconstrained structure functions of the nucleon, beyond the usual Dirac and Pauli form factors. In addition, they show the sensitivity to bound nucleon form factors using the reaction 4He({rvec e},e{prime},{rvec p}){sup 3}H. A nucleon embedded in a nucleus represents a complex system. Firstly, the bound nucleon is necessarily off-shell and in principle a complete understanding of the dynamical structure of the nucleon is required in order to calculate its off-shell electromagnetic interaction. Secondly, one faces the possibility of genuine medium effects, such as for example quark-exchange contributions. Furthermore, the electromagnetic coupling to the bound nucleon is dependent on the nuclear dynamics through the self-energy of the nucleon in the nuclear medium.

  1. Design and characterization of a neutron calibration facility for the study of sub-keV nuclear recoils

    NASA Astrophysics Data System (ADS)

    Barbeau, P. S.; Collar, J. I.; Whaley, P. M.

    2007-05-01

    We have designed and built a highly monochromatic 24 keV neutron beam at the Kansas State University Triga Mark-II reactor, as part of an experimental effort to demonstrate sensitivity in a large-mass detector to the ultra-low energy recoils expected from coherent neutrino-nucleus elastic scattering. The beam characteristics were chosen so as to mimic the soft recoil energies expected from reactor antineutrinos in a variety of targets, allowing to understand the response of dedicated detector technologies in this yet unexplored sub-keV recoil range. A full characterization of the beam properties (intensity, monochromaticity, contaminations, beam profile) is presented, together with first tests of the calibration facility using proton recoils in organic scintillator.

  2. Ionization and scintillation of nuclear recoils in gaseous xenon

    NASA Astrophysics Data System (ADS)

    Renner, J.; Gehman, V. M.; Goldschmidt, A.; Matis, H. S.; Miller, T.; Nakajima, Y.; Nygren, D.; Oliveira, C. A. B.; Shuman, D.; Álvarez, V.; Borges, F. I. G.; Cárcel, S.; Castel, J.; Cebrián, S.; Cervera, A.; Conde, C. A. N.; Dafni, T.; Dias, T. H. V. T.; Díaz, J.; Esteve, R.; Evtoukhovitch, P.; Fernandes, L. M. P.; Ferrario, P.; Ferreira, A. L.; Freitas, E. D. C.; Gil, A.; Gómez, H.; Gómez-Cadenas, J. J.; González-Díaz, D.; Gutiérrez, R. M.; Hauptman, J.; Hernando Morata, J. A.; Herrera, D. C.; Iguaz, F. J.; Irastorza, I. G.; Jinete, M. A.; Labarga, L.; Laing, A.; Liubarsky, I.; Lopes, J. A. M.; Lorca, D.; Losada, M.; Luzón, G.; Marí, A.; Martín-Albo, J.; Martínez, A.; Moiseenko, A.; Monrabal, F.; Monserrate, M.; Monteiro, C. M. B.; Mora, F. J.; Moutinho, L. M.; Muñoz Vidal, J.; Natal da Luz, H.; Navarro, G.; Nebot-Guinot, M.; Palma, R.; Pérez, J.; Pérez Aparicio, J. L.; Ripoll, L.; Rodríguez, A.; Rodríguez, J.; Santos, F. P.; dos Santos, J. M. F.; Seguí, L.; Serra, L.; Simón, A.; Sofka, C.; Sorel, M.; Toledo, J. F.; Tomás, A.; Torrent, J.; Tsamalaidze, Z.; Veloso, J. F. C. A.; Villar, J. A.; Webb, R. C.; White, J.; Yahlali, N.

    2015-09-01

    Ionization and scintillation produced by nuclear recoils in gaseous xenon at approximately 14 bar have been simultaneously observed in an electroluminescent time projection chamber. Neutrons from radioisotope α-Be neutron sources were used to induce xenon nuclear recoils, and the observed recoil spectra were compared to a detailed Monte Carlo employing estimated ionization and scintillation yields for nuclear recoils. The ability to discriminate between electronic and nuclear recoils using the ratio of ionization to primary scintillation is demonstrated. These results encourage further investigation on the use of xenon in the gas phase as a detector medium in dark matter direct detection experiments.

  3. Protein Folding-How and Why: By Hydrogen Exchange, Fragment Separation, and Mass Spectrometry.

    PubMed

    Englander, S Walter; Mayne, Leland; Kan, Zhong-Yuan; Hu, Wenbing

    2016-07-01

    Advanced hydrogen exchange (HX) methodology can now determine the structure of protein folding intermediates and their progression in folding pathways. Key developments over time include the HX pulse labeling method with nuclear magnetic resonance analysis, the fragment separation method, the addition to it of mass spectrometric (MS) analysis, and recent improvements in the HX MS technique and data analysis. Also, the discovery of protein foldons and their role supplies an essential interpretive link. Recent work using HX pulse labeling with MS analysis finds that a number of proteins fold by stepping through a reproducible sequence of native-like intermediates in an ordered pathway. The stepwise nature of the pathway is dictated by the cooperative foldon unit construction of the protein. The pathway order is determined by a sequential stabilization principle; prior native-like structure guides the formation of adjacent native-like structure. This view does not match the funneled energy landscape paradigm of a very large number of folding tracks, which was framed before foldons were known and is more appropriate for the unguided residue-level search to surmount an initial kinetic barrier rather than for the overall unfolded-state to native-state folding pathway. PMID:27145881

  4. Numerical simulations of spiral galaxy formation and recoiling black holes

    NASA Astrophysics Data System (ADS)

    Guedes, Javiera M.

    This thesis discusses two major topics in regard to the formation and evolution of galaxies and their central massive black holes (MBH). Part 1 explores the detectability of recoiling massive back as kinematically and spatially offset active galactic nuclei (AGN). Chapter 3 is devoted to understanding the effect of an aspherical dark matter potential on the trajectories of the MBHs. This is done through collisionless N-body simulations of kicked black holes in the Via Lactea I halo and through a semi-analytical model that accounts for the evolution of the halo's triaxiality as a function of radius over cosmic time. We find that the return time of MBHs that wander through a differentially triaxial halo is significantly extended in comparison with spherical models. This is because their trajectories are become highly non-radial which prevents them from passing near the halo's center, where dynamical friction is most efficient. Chapter 4 puts recoiling MBHs into context. Here we carry out N-body + SPH simulations of recoiling MBHs in high-resolution galaxy mergers with mass ratios 1:1 (Mayer et al. 2007), 1:4, and 1:10 (Callegari et al. 2009). We study not only the trajectories and return times of these black holes, but also their detectability as spatially/kinematically offset AGN. We find that the probability of detection of these MBHs is extremely low. The detection of large kinematic offsets requires that the MBH have relative offset velocities Deltav > 600km s-1 at the time of observation. This is unlikely due to (1) the low probability of large recoils to occur from a general-relativistic viewpoint, and (2) the short time scale during which the MBH can sustain large velocities even if the initial kick is high. The large amounts of gas funneled to the center of the host potential during mergers also prevents MBHs from reaching large apocenter distances, which hampers their detection as spatially offset AGN, especially at high redshift when recoil events are

  5. A Measurement of the Recoil Polarization of Electroproduced {Lambda}(1116)

    SciTech Connect

    Simeon McAleer

    2002-01-01

    The CEBAF Large Acceptance Spectrometer at the Thomas Jefferson National Laboratory was used to study the reaction e + p {yields} e{prime} + K{sup +} + {Lambda}(1116) for events where {Lambda}(1116) subsequently decayed via the channel {Lambda}(1116) {yields} p + {pi}{sup -}. Data were taken at incident electron beam energies of 2.5, 4.0, and 4.2 GeV during the 1999 E1C run period. They hyperon production spectra span the Q{sup 2} range from 0.5 to 2.8 GeV{sup 2} and nearly the entire range in the center of mass angles. The proton angular distribution in the {Lambda}(1116) rest frame is used to deduce the recoil polarization of the hyperon, and the W and cos {theta}{sub cm}{sup K+} dependence of the recoil polarization will be presented. The data show sizeable negative polarizations for the {Lambda}(1116) as a function of both cos {theta}{sub cm}{sup K+} and W.

  6. Recoil polarization and beam-recoil double polarization measurement of eta electroproduction on the proton in the region of the S11(1535) resonance.

    PubMed

    Merkel, H; Achenbach, P; Ayerbe Gayoso, C; Bernauer, J C; Böhm, R; Bosnar, D; Cheymol, B; Distler, M O; Doria, L; Fonvieille, H; Friedrich, J; Janssens, P; Makek, M; Müller, U; Nungesser, L; Pochodzalla, J; Potokar, M; Sánchez Majos, S; Schlimme, B S; Sirca, S; Tiator, L; Walcher, Th; Weinriefer, M

    2007-09-28

    The beam-recoil double polarization P(x')(h) and P(z')(h) and the recoil polarization P(y') were measured for the first time for the p(e,e'p)eta reaction at a four-momentum transfer of Q(2) = 0.1 GeV(2)/c(2) and a center of mass production angle of theta = 120 degrees at the Mainz Microtron MAMI-C. With a center of mass energy range of 1500 MeV

  7. Cavity cooling below the recoil limit.

    PubMed

    Wolke, Matthias; Klinner, Julian; Keßler, Hans; Hemmerich, Andreas

    2012-07-01

    Conventional laser cooling relies on repeated electronic excitations by near-resonant light, which constrains its area of application to a selected number of atomic species prepared at moderate particle densities. Optical cavities with sufficiently large Purcell factors allow for laser cooling schemes, avoiding these limitations. Here, we report on an atom-cavity system, combining a Purcell factor above 40 with a cavity bandwidth below the recoil frequency associated with the kinetic energy transfer in a single photon scattering event. This lets us access a yet-unexplored regime of atom-cavity interactions, in which the atomic motion can be manipulated by targeted dissipation with sub-recoil resolution. We demonstrate cavity-induced heating of a Bose-Einstein condensate and subsequent cooling at particle densities and temperatures incompatible with conventional laser cooling. PMID:22767925

  8. Recoil Polarization for {delta} Excitation in Pion Electroproduction

    SciTech Connect

    Kelly, J.J.; Beise, E.J.; Breuer, H.; Chang, C.C.; Chant, N.S.; Roos, P.G.; Roche, R.E.; McAleer, S.; Meekins, D.; Chai, Z.; Gayou, O.; Bertozzi, W.; Gilad, S.; Higinbotham, D.W.; Rvachev, M.; Sirca, S.; Suleiman, R.; Zheng, X.; Zhu, L.; Jones, M.K.

    2005-09-02

    We measured angular distributions of recoil-polarization response functions for neutral pion electroproduction for W=1.23 GeV at Q{sup 2}=1.0 (GeV/c){sup 2}, obtaining 14 separated response functions plus 2 Rosenbluth combinations; of these, 12 have been observed for the first time. Dynamical models do not describe quantities governed by imaginary parts of interference products well, indicating the need for adjusting magnitudes and phases for nonresonant amplitudes. We performed a nearly model-independent multipole analysis and obtained values for Re (S{sub 1+}/M{sub 1+})=-(6.84{+-}0.15)% and Re (E{sub 1+}/M{sub 1+})=-(2.91{+-}0.19)% that are distinctly different from those from the traditional Legendre analysis based upon M{sub 1+} dominance and l{sub {pi}}{<=}1 truncation.

  9. Recoil polarization for delta excitation in pion electroproduction.

    PubMed

    Kelly, J J; Roché, R E; Chai, Z; Jones, M K; Gayou, O; Sarty, A J; Frullani, S; Aniol, K; Beise, E J; Benmokhtar, F; Bertozzi, W; Boeglin, W U; Botto, T; Brash, E J; Breuer, H; Brown, E; Burtin, E; Calarco, J R; Cavata, C; Chang, C C; Chant, N S; Chen, J-P; Coman, M; Crovelli, D; De Leo, R; Dieterich, S; Escoffier, S; Fissum, K G; Garde, V; Garibaldi, F; Georgakopoulus, S; Gilad, S; Gilman, R; Glashausser, C; Hansen, J-O; Higinbotham, D W; Hotta, A; Huber, G M; Ibrahim, H; Iodice, M; de Jager, C W; Jiang, X; Klimenko, A; Kozlov, A; Kumbartzki, G; Kuss, M; Lagamba, L; Laveissière, G; Lerose, J J; Lindgren, R A; Liyanage, N; Lolos, G J; Lourie, R W; Margaziotis, D J; Marie, F; Markowitz, P; McAleer, S; Meekins, D; Michaels, R; Milbrath, B D; Mitchell, J; Nappa, J; Neyret, D; Perdrisat, C F; Potokar, M; Punjabi, V A; Pussieux, T; Ransome, R D; Roos, P G; Rvachev, M; Saha, A; Sirca, S; Suleiman, R; Strauch, S; Templon, J A; Todor, L; Ulmer, P E; Urciuoli, G M; Weinstein, L B; Wijesooriya, K; Wojtsekhowski, B; Zheng, X; Zhu, L

    2005-09-01

    We measured angular distributions of recoil-polarization response functions for neutral pion electroproduction for W = 1.23 GeV at Q(2) = 1.0 (GeV/c)(2), obtaining 14 separated response functions plus 2 Rosenbluth combinations; of these, 12 have been observed for the first time. Dynamical models do not describe quantities governed by imaginary parts of interference products well, indicating the need for adjusting magnitudes and phases for nonresonant amplitudes. We performed a nearly model-independent multipole analysis and obtained values for Re (S(1+)/M(1+)) = -(6.84 +/- 0.15)% and Re (E(1+)/M(1+)) = -(2.91 +/- 0.19)% that are distinctly different from those from the traditional Legendre analysis based upon M1+ dominance and ll(pi) < or = 1 truncation. PMID:16196919

  10. Recoil Polarization for Delta Excitation in Pion Electroproduction

    SciTech Connect

    J. J. Kelly; R. E. Roche; Z. Chai; M. K. Jones; O. Gayou; A. J. Sarty; S. Frullani; K. Aniol; E. J. Beise; F. Benmokhtar; W. Bertozzi; W. U. Boeglin; T. Botto; E. J. Brash; H. Breuer; E. Brown; E. Burtin; J. R. Calarco; C. Cavata; C. C. Chang; N. S. Chant; J.-P. Chen; M. Coman; D. Crovelli; R. De Leo; S. Dieterich; S. Escoffier; K. G. Fissum; V. Garde; F. Garibaldi; S. Georgakopoulus; S. Gilad; R. Gilman; C. Glashausser; J.-O. Hansen; D. W. Higinbotham; A. Hotta; G. M. Huber; H. Ibrahim; M. Iodice; C. W. de Jager; X. Jiang; A. Klimenko; A. Kozlov; G. Kumbartzki; M. Kuss; L. Lagamba; G. Laveissiere; J. J. LeRose; R. A. Lindgren; N. Liyanage; G. J. Lolos; R. W. Lourie; D. J. Margaziotis; F. Marie; P. Markowitz; S. McAleer; D. Meekins; R. Michaels; B. D. Milbrath; J. Mitchell; J. Nappa; D. Neyret; C. F. Perdrisat; M. Potokar; V. A. Punjabi; T. Pussieux; R. D. Ransome; P. G. Roos; M. Rvachev; A. Saha; S. Sirca; R. Suleiman; S. Strauch; J. A. Templon; L. Todor; P. E. Ulmer; G. M. Urciuoli; L. B. Weinstein; K. Wijesooriya; B. Wojtsekhowski; X. Zheng; and L. Zhu

    2005-08-01

    We measured angular distributions of recoil-polarization response functions for neutral pion electroproduction for W=1.23 GeV at Q{sup 2}=1.0 (GeV/c){sup 2}, obtaining 14 separated response functions plus 2 Rosenbluth combinations; of these, 12 have been observed for the first time. Dynamical models do not describe quantities governed by imaginary parts of interference products well, indicating the need for adjusting magnitudes and phases for nonresonant amplitudes. We performed a nearly model-independent multipole analysis and obtained values for Re(S1+/M1+)=-(6.84+/-0.15)% and Re(E1+/M1+)=-(2.91+/-0.19)% that are distinctly different from those from the traditional Legendre analysis based upon M1+ dominance and sp truncation.

  11. Isobar separation by time-of-flight mass spectrometry for low-energy radioactive ion beam facilities

    NASA Astrophysics Data System (ADS)

    Plaß, Wolfgang R.; Dickel, Timo; Czok, Ulrich; Geissel, Hans; Petrick, Martin; Reinheimer, Katrin; Scheidenberger, Christoph; Yavor, Mikhail I.

    2008-10-01

    A multiple-reflection time-of-flight mass spectrometer (MR-TOF-MS) system for low-energy radioactive ion beam facilities has been developed, which can be used for (i) isobar separation and (ii) direct mass measurements of very short-lived nuclei with half-lives of about 1 ms or longer, and (iii) for identification and diagnosis of the ion beam by mass spectrometry. The system has been designed and simulated, and individual subsystems have been built and characterized experimentally. An injection trap for cooling and bunching of the ion beam has been developed, and cooling times of less than one millisecond have been achieved. The performance of the MR-TOF-MS was characterized using the isobaric doublet of carbon monoxide and nitrogen molecular ions. A mass resolving power of 105 (FWHM) has been obtained even with an uncooled ion population. The separator capabilities of the MR-TOF-MS have been demonstrated by removing either carbon monoxide or nitrogen ions from the beam in a Bradbury-Nielsen Gate after a flight time of 320 μs. The separation power achieved is thus at least 7000 (FWHM) and increases for longer time-of-flight. An energy buncher stage has been designed that compresses the energy spread of the beam after the separation and facilitates efficient injection of the selected ions into an accumulation trap prior to transfer of the ions to experiments downstream of the MR-TOF-MS.

  12. Two-dimensional separation of ionic species by hyphenation of capillary ion chromatography × capillary electrophoresis-mass spectrometry.

    PubMed

    Beutner, Andrea; Kochmann, Sven; Mark, Jonas Josef Peter; Matysik, Frank-Michael

    2015-03-17

    The separation of complex mixtures such as biological or environmental samples requires high peak capacities, which cannot be established with a single separation technique. Therefore, multidimensional systems are in demand. In this work, we present the hyphenation of the two most important (orthogonal) techniques in ion analysis, namely, ion chromatography (IC) and capillary electrophoresis (CE), in combination with mass spectrometry. A modulator was developed ensuring a well-controlled coupling of IC and CE separations. Proof-of-concept measurements were performed using a model system consisting of nucleotides and cyclic nucleotides. The data are presented in a multidimensional contour plot. Analyte stacking in the CE separation could be exploited on the basis of the fact that the suppressed IC effluent is pure water. PMID:25708415

  13. Sound production by a recoiling system in the pempheridae and terapontidae.

    PubMed

    Parmentier, Eric; Fine, Michael L; Mok, Hin-Kiu

    2016-06-01

    Sound-producing mechanisms in fishes are extraordinarily diversified. We report here original mechanisms of three species from two families: the pempherid Pempheris oualensis, and the terapontids Terapon jarbua and Pelates quadrilineatus. All sonic mechanisms are built on the same structures. The rostral part of the swimbladder is connected to a pair of large sonic muscles from the head whereas the posterior part is fused with bony widenings of vertebral bodies. Two bladder regions are separated by a stretchable fenestra that allows forward extension of the anterior bladder during muscle contraction. A recoiling apparatus runs between the inner face of the anterior swimbladder and a vertebral body expansion. The elastic nature of the recoiling apparatus supports its role in helping the swimbladder to recover its initial position during sonic muscle relaxation. This system should aid fast contraction (between 100 and 250Hz) of sonic muscles. There are many differences between species in terms of the swimbladder and its attachments to the vertebral column, muscle origins, and morphology of the recoiling apparatus. The recoiling apparatus found in the phylogenetically-related families (Glaucosomatidae, Pempheridae, Terapontidae) could indicate a new character within the Percomorpharia. J. Morphol. 277:717-724, 2016. © 2016 Wiley Periodicals, Inc. PMID:27021214

  14. Multidimensional Mass Spectrometry Coupled with Separation by Polarity or Shape for the Characterization of Sugar-Based Nonionic Surfactants.

    PubMed

    Katzenmeyer, Bryan C; Hague, Shayna F; Wesdemiotis, Chrys

    2016-01-01

    Mass spectrometry (MS) and tandem mass spectrometry (MS/MS) were interfaced with ultra-performance liquid chromatography (UPLC) and ion mobility (IM) separation to characterize a complex nonionic surfactant, consisting of a methylated glucose core (glucam) conjugated with poly(ethylene oxide) (PEO(n)) branches that were partially esterified with stearic acid to form ethoxylated glucam (PEO(n)-glucam) stearates. Reverse-phase LC-MS afforded fast separation according to polarity into five major fractions. Accurate mass measurements of the ions in the mass spectra extracted from these fractions enabled conclusive identification of six components in the surfactant, including PEO(n)-glucam mono-, di-, and tristearates as well as free and esterified PEO(n) as byproducts. MS/MS experiments provided corroborating evidence for the fatty acid content in each fraction based on the number of stearic acid losses observed. With IM-MS, the total surfactant ions were separated according to charge and shape into four distinct bands. Extracted mass spectra confirmed the presence of two disaccharide stearates in the surfactant, which were undetectable by LC-MS. PEO(n)-glucam tristearates were, however, not observed upon IM-MS. Hence, LC-MS and IM-MS unveiled complementary compositional insight. With each method, certain components were particularly well separated from other ingredients (by either polarity or shape), to be detected with confidence. Consequently, combined LC-MS and IM-MS offer a superior approach for the characterization of surfactants and other amphiphilic polymers and for the differentiation of similarly composed amphiphilic blends. It is finally noteworthy that NH4(+) charges minimized chemical noise in MS mode and Li(+) charges maximized the fragmentation efficiency in MS/MS mode. PMID:26642239

  15. Protein separation and characterization by np-RP-HPLC followed by intact MALDI-TOF mass spectrometry and peptide mass mapping analyses

    PubMed Central

    Dauly, Claire; Perlman, David H.; Costello, Catherine E.; McComb, Mark E.

    2008-01-01

    Due to their complexity, the separation of intact proteins from complex mixtures is an important step to comparative proteomics and the identification and characterization of the proteins by mass spectrometry (MS). In the study reported, we evaluated the use of non-porous-reversed-phase (np-RP) HPLC for intact protein separation prior to MS analyses. The separation system was characterized and compared to 1D-SDS-PAGE electrophoresis in terms of resolution and sensitivity. We demonstrate that np-RP HPLC protein separation is highly reproducible and provides intact protein fractions which can be directly analyzed by MALDI-TOF MS for intact molecular weight determination. An in-well digestion protocol was developed, allowing for rapid protein identification by peptide mass fingerprinting (PMF) and resulted in comparable or improved peptide recovery compared with in-gel digestion. The np-RP sensitivity of detection by UV absorbance at 214 nm for intact proteins was at the low ng level and the sensitivity of peptide analysis by MALDI-TOF MS was in the 10–50 pg level. A membrane protein fraction was characterized to demonstrate application of this methodology. Among the identified proteins, multiple forms of vimentin were observed. Overall we demonstrate that np-RP HPLC followed by MALDI-TOF MS allows for rapid, sensitive and reproducible protein fractionation and very specific protein characterization by integration of PMF analysis with MS intact molecular weight information. PMID:16823977

  16. Thermal recoil force, telemetry, and the Pioneer anomaly

    SciTech Connect

    Toth, Viktor T.; Turyshev, Slava G.

    2009-02-15

    Precision navigation of spacecraft requires accurate knowledge of small forces, including the recoil force due to anisotropies of thermal radiation emitted by spacecraft systems. We develop a formalism to derive the thermal recoil force from the basic principles of radiative heat exchange and energy-momentum conservation. The thermal power emitted by the spacecraft can be computed from engineering data obtained from flight telemetry, which yields a practical approach to incorporate the thermal recoil force into precision spacecraft navigation. Alternatively, orbit determination can be used to estimate the contribution of the thermal recoil force. We apply this approach to the Pioneer anomaly using a simulated Pioneer 10 Doppler data set.

  17. Measurement of Nuclear Recoils in the CDMS II Dark Matter Search

    SciTech Connect

    Fallows, Scott Mathew

    2014-12-01

    The Cryogenic Dark Matter Search (CDMS) experiment is designed to directly detect elastic scatters of weakly-interacting massive dark matter particles (WIMPs), on target nuclei in semiconductor crystals composed of Si and Ge. These scatters would occur very rarely, in an overwhelming background composed primarily of electron recoils from photons and electrons, as well as a smaller but non-negligible background of WIMP-like nuclear recoils from neutrons. The CDMS II generation of detectors simultaneously measure ionization and athermal phonon signals from each scatter, allowing discrimination against virtually all electron recoils in the detector bulk. Pulse-shape timing analysis allows discrimination against nearly all remaining electron recoils taking place near detector surfaces. Along with carefully limited neutron backgrounds, this experimental program allowed for \\background- free" operation of CDMS II at Soudan, with less than one background event expected in each WIMP-search analysis. As a result, exclusionary upper-limits on WIMP-nucleon interaction cross section were placed over a wide range of candidate WIMP masses, ruling out large new regions of parameter space.

  18. Direct analysis of nine pharmaceuticals in culture media by use of cartridge separation with electrospray mass spectrometric detection.

    PubMed

    Li, Xing-Fang; Ma, Mingsheng; Tam, Yun K

    2002-09-01

    A 2-cm cartridge has been used for separation before electrospray mass spectrometric analysis of pharmaceutical compounds in cell culture media, alleviating the need for sample extraction and desalting procedures. Nine representative pharmaceuticals listed in the biopharmaceutical classification system (BCS) were chosen as the candidate compounds and Hank's balanced salt solution with Hepes buffer (HBSS-Hepes buffer) was used as the cell-culture medium in an effort to study permeability of chemicals through cell monolayers. Effects of several conditions, e.g. pH and buffer concentration in the mobile phase, flow rate, and temperature on separation efficiency were examined. The nine pharmaceuticals were separated within 2 min by use of a 2-cm C(8) cartridge. Relative standard deviations (RSD) from repeated analysis within the same day or over five days were 0.03-0.2% for retention times and 0.6-5.3% for peak areas; antipyrine was used as internal standard. Calibration curves based on peak-area measurements were linear over the range 0.1-20 micro mol L(-1). The HBSS-Hepes buffer did not interfere with separation and detection; identical separation and peak intensity were obtained when the samples were separately prepared in distilled water or in the culture medium. PMID:12207243

  19. Resolving Trends in Antarctic Ice Sheet Mass Loss and Glacio-isostatic Adjustment Through Spatio-temporal Source-separation

    NASA Astrophysics Data System (ADS)

    Bamber, J. L.; Schoen, N.; Zammit-Mangion, A.; Rougier, J.; Flament, T.; Luthcke, S. B.; Petrie, E. J.; Rémy, F.

    2013-12-01

    There remains considerable inconsistency between different methods and approaches for determining ice mass trends for Antarctica from satellite observations. There are three approaches that can provide near global coverage for mass trends: altimetry, gravimetry and mass budget calculations. All three approaches suffer from a source separation problem where other geophysical processes limit the capability of the method to resolve the origin and magnitude of a mass change. A fourth approach, GPS vertical motion, provides localised estimates of mass change due to elastic uplift and an indirect estimate of GIA. Each approach has different source separation issues and different spatio-temporal error characteristics. In principle, it should be possible to combine the data and process covariances to minimize the uncertainty in the solution and to produce robust, posterior errors for the trends. In practice, this is a challenging problem in statistics because of the large number of degrees of freedom, the variable spatial and temporal sampling between the different observations and the fact that some processes remain under-sampled, such as firn compaction. Here, we present a novel solution to this problem using the latest methods in statistical modelling of spatio-temporal processes. We use Bayesian hierarchical modelling and employ stochastic partial differential equations to capture our physical understanding of the key processes that influence our observations. Due to the huge number of observations involved (> 10^8) methods are required to reduce the dimensionality of the problem and care is required in treatment of the observations as they are not independent. Here, we focus mainly on the results rather than the full suite of methods and we present time evolving fields of surface mass balance, ice dynamic-driven mass loss, and firn compaction for the period 2003-2009, derived from a combination of ICESat, ENVISAT, GRACE, InSAR, GPS and regional climate model output

  20. Heat and mass transfer in porous media phase separation at temperatures below the lambda-point of He-4

    NASA Technical Reports Server (NTRS)

    Yuan, S. W. K.; Frederking, T. H. K.

    1986-01-01

    Newtonian fluid motion, coupled to heat transfer via latent heat of phase transition, is well known from numerous studies of condensation and boiling. Considerably less knowledge is available for vapor-liquid phase separation in the absence of gravity effect on the transport phenomena. The present studies are focused on heat and mass transfer associated with vapor-liquid phase separation required for long-term storage of the cryogen liquid He II in space vessels. Though space conditions are the dominant mode of interest in advanced equipment, e.g. IR telescopes, the systems may be operated in principle during terrestrial conditions. The latter are considered in the present work. It emphasizes the linear regime including an extrapolation based on variable thermophysical properties. Data taken with a phase separation approach show departures from the linear regime prediction. They agree with a transport equation proposed for the nonlinear, turbulent regime.

  1. Neutron star recoils from anisotropic supernovae.

    NASA Astrophysics Data System (ADS)

    Janka, H.-T.; Mueller, E.

    1994-10-01

    Refering to recent hydrodynamical computations (Herant et al. 1992; Janka & Mueller 1993a) it is argued that neutron star kicks up to a few hundred km/s might be caused by a turbulent overturn of the matter between proto-neutron star and supernova shock during the early phase of the supernova explosion. These recoil speeds ("kick velocities") may be of the right size to explain the measured proper motions of most pulsars and do not require the presence of magnetic fields in the star. It is also possible that anisotropic neutrino emission associated with convective processes in the surface layers of the nascent neutron star (Burrows & Fryxell 1992; Janka & Mueller 1993b; Mueller 1993) provides an acceleration mechanism (Woosley 1987), although our estimates indicate that the maximum attainable velocities are around 200km/s. Yet, it turns out to be very unlikely that the considered stochastic asymmetries of supernova explosions are able to produce large enough recoils to account for pulsar velocities in excess of about 500km/s, which can be found in the samples of Harrison et al. (1993) and Taylor et al. (1993). It is concluded that other acceleration mechanisms have to be devised to explain the fast motion of PSR 2224+65 (transverse speed >=800km/s Cordes et al. 1993) and the high-velocities deduced from associations between supernova remnants and nearby young pulsars (e.g., Frail & Kulkarni 1991; Stewart et al. 1993; Caraveo 1993).

  2. α -decay chains of recoiled superheavy nuclei: A theoretical study

    NASA Astrophysics Data System (ADS)

    Niyti, Sawhney, Gudveen; Sharma, Manoj K.; Gupta, Raj K.

    2015-05-01

    A systematic theoretical study of α -decay half-lives in the superheavy mass region of the periodic table of elements is carried out by extending the quantum-mechanical fragmentation theory based on the preformed cluster model (PCM) to include temperature (T ) dependence in its built-in preformation and penetration probabilities of decay fragments. Earlier, the α -decay chains of the isotopes of Z =115 were investigated by using the standard PCM for spontaneous decays, with"hot-optimum" orientation effects included, which required a constant scaling factor of 104 to approach the available experimental data. In the present approach of the PCM (T ≠0 ), the temperature effects are included via the recoil energy of the residual superheavy nucleus (SHN) left after x -neutron emission from the superheavy compound nucleus. The important result is that the α -decay half-lives calculated by the PCM (T ≠0 ) match the experimental data nearly exactly, without using any scaling factor of the type used in the PCM. Note that the PCM (T ≠0 ) is an equivalent of the dynamical cluster-decay model for heavy-ion collisions at angular momentum ℓ =0 . The only parameter of model is the neck-length parameter Δ R , which for the calculated half-lives of α -decay chains of various isotopes of Z =113 to 118 nuclei formed in "hot-fusion" reactions is found to be nearly constant, i.e., Δ R ≈0.95 ±0.05 fm for all the α -decay chains studied. The use of recoiled residue nucleus as a secondary heavy-ion beam for nuclear reactions has also been suggested in the past.

  3. Relativistic calculations of the nuclear recoil effect in highly charged Li-like ions

    NASA Astrophysics Data System (ADS)

    Zubova, N. A.; Shabaev, V. M.; Tupitsyn, I. I.; Plunien, G.

    2013-09-01

    Relativistic theory of the nuclear recoil effect in highly charged Li-like ions is considered within the Breit approximation. The normal mass shift (NMS) and the relativistic NMS (RNMS) are calculated by perturbation theory to zeroth and first orders in the parameter 1/Z. The calculations are performed using the dual kinetic balance method with the basis functions constructed from B-splines. The results of the calculations are compared with the theoretical values obtained by other methods.

  4. New reagents for enhanced liquid chromatographic separation and charging of intact protein ions for electrospray ionization mass spectrometry.

    PubMed

    Valeja, Santosh G; Tipton, Jeremiah D; Emmett, Mark R; Marshall, Alan G

    2010-09-01

    Electrospray ionization produces multiply charged ions, thereby lowering the mass-to-charge ratio for peptides and small proteins to a range readily accessed by quadrupole ion trap, orbitrap, and ion cyclotron resonance (ICR) mass analyzers (m/z = 400-2000). For Fourier transform mass analyzers (orbitrap and ICR), higher charge also improves signal-to-noise ratio, mass resolution, and mass accuracy. Addition of m-nitrobenzyl alcohol (m-NBA) or sulfolane has previously been shown to increase the charge states of proteins. Moreover, polar aprotic dimethylformamide (DMF) improves chromatographic separation of proteolytic peptides for mass analysis of solution-phase protein hydrogen/deuterium exchange for improved (78-96%) sequence coverage. Here, we show that addition of each of the various modifiers (DMF, thiodiglycol, dimethylacetamide, dimethylsulfoxide, and N-methylpyrrolidone) can significantly increase the charge states of proteins up to 78 kDa. Moreover, incorporation of the same modifiers into reversed-phase liquid chromatography solvents improves sensitivity, charging, and chromatographic resolution for intact proteins. PMID:20704305

  5. Constraints on the Nature of CID-42: Recoil Kick or Supermassive Black Hole Pair?

    NASA Technical Reports Server (NTRS)

    Blecha, Laura; Civano, Francesca; Elvis, Martin; Loeb, Abraham

    2012-01-01

    The galaxy CXOC J100043.1+020637, also known as CID-42, is a highly unusual object. An apparent galaxy merger remnant, it displays signatures of both an inspiraling, kiloparsecscale active galactic nucleus (AGN) pair and of a recoiling AGN with a kick velocity approximately greater than 1300 km s(exp -1). Among recoiling AGN candidates, CID-42 alone has both spatial offsets (in optical and X-ray bands) and spectroscopic offsets. In order to constrain the relative likelihood of both scenarios, we develop models using hydrodynamic galaxy merger simulations coupled with radiative transfer calculations. Our gas-rich, major merger models are generally well matched to the galactic morphology and to the inferred stellar mass and star formation rate. We show that a recoiling supermassive black hole (SMBH) in CID-42 should be observable as an AGN at the time of observation. However, in order for the recoiling AGN to produce narrow-line emission, it must be observed shortly after the kick while it still inhabits a dense gaseous region, implying a large total kick velocity (vk approximately greater than 2000 km s(exp -1)). For the dual AGN scenario, an unusually large broad-line offset is required, and the best match to the observed morphology requires a galaxy that is less luminous than CID-42. Further, the lack of X-ray emission from one of the two optical nuclei is not easily attributed to an intrinsically quiescent SMBH or to a Compton-thick galactic environment. While the current data do not allow either the recoiling or the dual AGN scenario for CID-42 to be excluded, our models highlight the most relevant parameters for distinguishing these possibilities with future observations. In particular, high-quality, spatially-resolved spectra that can pinpoint the origin of the broad and narrow line features will be critical for determining the nature of this unique source.

  6. Constraints on the nature of CID-42: recoil kick or supermassive black hole pair?

    NASA Astrophysics Data System (ADS)

    Blecha, Laura; Civano, Francesca; Elvis, Martin; Loeb, Abraham

    2013-01-01

    The galaxy CXOC J100043.1+020637, also known as CID-42, is a highly unusual object. As an apparent galaxy merger remnant, it displays signatures of both an inspiraling, kiloparsec-scale active galactic nucleus (AGN) pair and of a recoiling AGN with a kick velocity of ≳ 1300 km s-1. Among recoiling AGN candidates, CID-42 alone has both spatial offsets (in optical and X-ray bands) and spectroscopic offsets. In order to constrain the relative likelihood of both scenarios, we develop models using hydrodynamic galaxy merger simulations coupled with radiative transfer calculations. Our gas-rich, major merger models are generally well matched to the galactic morphology and to the inferred stellar mass and star formation rate. We show that a recoiling supermassive black hole (SMBH) in CID-42 should be observable as an AGN at the time of observation. However, in order for the recoiling AGN to produce narrow-line emission, it must be observed shortly after the kick while it still inhabits a dense gaseous region, implying a large total kick velocity (vk ≳ 2000 km s-1). For the dual AGN scenario, an unusually large broad-line offset is required, and the best match to the observed morphology requires a galaxy that is less luminous than CID-42. Further, the lack of X-ray emission from one of the two optical nuclei is not easily attributed to an intrinsically quiescent SMBH or to a Compton thick galactic environment. While the current data do not allow either the recoiling or the dual AGN scenario for CID-42 to be excluded, our models highlight the most relevant parameters for distinguishing these possibilities with future observations. In particular, high-quality, spatially resolved spectra that can pinpoint the origin of the broad-line and narrow-line features will be critical for determining the nature of this unique source.

  7. Strong Lensing by Subhalos in the Dwarf Galaxy Mass Range. I. Image Separations

    NASA Astrophysics Data System (ADS)

    Zackrisson, E.; Riehm, T.; Möller, O.; Wiik, K.; Nurmi, P.

    2008-09-01

    The cold dark matter scenario predicts that a large number of dark subhalos should be located within the halo of each Milky Way-sized galaxy. One telltale signature of such dark subhalos could be additional milliarcsecond-scale image splitting of quasars previously known to be multiply imaged on arcsecond scales. Here we estimate the image separations for the subhalo density profiles favored by recent N-body simulations and compare these to the angular resolution of both existing and upcoming observational facilities. We find that the image separations produced are very sensitive to the exact subhalo density profile assumed, but in all cases they are considerably smaller than previous estimates based on the premise that subhalos can be approximated by singular isothermal spheres. Only the most optimistic subhalo models produce image separations that would be detectable with current technology, and many models produce image separations that will remain unresolved with all telescopes expected to become available in the foreseeable future. Detections of dark subhalos through image-splitting effects will therefore be far more challenging than currently believed, albeit not necessarily impossible.

  8. Target protein separation and preparation by free-flow electrophoresis coupled with charge-to-mass ratio analysis.

    PubMed

    Shen, Qiao-Yi; Guo, Chen-Gang; Yan, Jian; Zhang, Qiang; Xie, Hai-Yang; Jahan, Sharmin; Fan, Liu-Yin; Xiao, Hua; Cao, Cheng-Xi

    2015-06-01

    Herein, a novel strategy was developed to separate and prepare target protein from complex sample by free-flow electrophoresis (FFE), which mainly based on the charge-to-mass ratio (C/M) analysis of proteins. The C/M values of three model proteins, namely Cytochrome C (Cyt C), myoglobin (Mb) and bovine serum albumin (BSA) were analyzed under different pH and the separation of these proteins was predicted by CLC Protein Workbench software. Series of experiments were performed to validate the proposed method. The obtained data showed high accordance with our prediction. In addition, the chamber buffer (CB) of FFE system was optimized to improve the resolution of separation. Meanwhile, in order to evaluate the analytical performance of the proposed method, Cyt C was extracted from swine heart and further separated by FFE based on C/M analysis. Results showed that Cyt C was completely separated from the crude sample and a purity of 96.9% was achieved. The activity of prepared Cyt C was 98.3%, which indicate that the proposed method is promising in a wide variety of research areas where the native properties of proteins should be maintained for downstream analysis. PMID:25890440

  9. A mass-balance model to separate and quantify colloidal and solute redistributions in soil

    USGS Publications Warehouse

    Bern, C.R.; Chadwick, O.A.; Hartshorn, A.S.; Khomo, L.M.; Chorover, J.

    2011-01-01

    Studies of weathering and pedogenesis have long used calculations based upon low solubility index elements to determine mass gains and losses in open systems. One of the questions currently unanswered in these settings is the degree to which mass is transferred in solution (solutes) versus suspension (colloids). Here we show that differential mobility of the low solubility, high field strength (HFS) elements Ti and Zr can trace colloidal redistribution, and we present a model for distinguishing between mass transfer in suspension and solution. The model is tested on a well-differentiated granitic catena located in Kruger National Park, South Africa. Ti and Zr ratios from parent material, soil and colloidal material are substituted into a mixing equation to quantify colloidal movement. The results show zones of both colloid removal and augmentation along the catena. Colloidal losses of 110kgm-2 (-5% relative to parent material) are calculated for one eluviated soil profile. A downslope illuviated profile has gained 169kgm-2 (10%) colloidal material. Elemental losses by mobilization in true solution are ubiquitous across the catena, even in zones of colloidal accumulation, and range from 1418kgm-2 (-46%) for an eluviated profile to 195kgm-2 (-23%) at the bottom of the catena. Quantification of simultaneous mass transfers in solution and suspension provide greater specificity on processes within soils and across hillslopes. Additionally, because colloids include both HFS and other elements, the ability to quantify their redistribution has implications for standard calculations of soil mass balances using such index elements. ?? 2011.

  10. On the minimum core mass for giant planet formation at wide separations

    SciTech Connect

    Piso, Ana-Maria A.; Youdin, Andrew N.

    2014-05-01

    In the core accretion hypothesis, giant planets form by gas accretion onto solid protoplanetary cores. The minimum (or critical) core mass to form a gas giant is typically quoted as 10 M {sub ⊕}. The actual value depends on several factors: the location in the protoplanetary disk, atmospheric opacity, and the accretion rate of solids. Motivated by ongoing direct imaging searches for giant planets, this study investigates core mass requirements in the outer disk. To determine the fastest allowed rates of gas accretion, we consider solid cores that no longer accrete planetesimals, as this would heat the gaseous envelope. Our spherical, two-layer atmospheric cooling model includes an inner convective region and an outer radiative zone that matches onto the disk. We determine the minimum core mass for a giant planet to form within a typical disk lifetime of 3 Myr. The minimum core mass declines with disk radius, from ∼8.5 M {sub ⊕} at 5 AU to ∼3.5 M {sub ⊕} at 100 AU, with standard interstellar grain opacities. Lower temperatures in the outer disk explain this trend, while variations in disk density are less influential. At all distances, a lower dust opacity or higher mean molecular weight reduces the critical core mass. Our non-self-gravitating, analytic cooling model reveals that self-gravity significantly affects early atmospheric evolution, starting when the atmosphere is only ∼10% as massive as the core.

  11. Reaction mechanisms in the system {sup 20}Ne+{sup 165}Ho: Measurement and analysis of forward recoil range distributions

    SciTech Connect

    Singh, D.; Ali, R.; Ansari, M. Afzal; Rashid, M. H.; Guin, R.; Das, S. K.

    2009-05-15

    Keeping in view the study of complete and incomplete fusion of heavy ions with a target, the forward recoil range distributions of several evaporation residues produced at 164 MeV {sup 20}Ne-ion beam energy have been measured for the system {sup 20}Ne+{sup 165}Ho. The recoil catcher activation technique followed by off-line gamma spectroscopy has been employed. Measured forward recoil range distributions of these evaporation residues show evidence of several incomplete fusion channels in addition to complete fusion. The entire and partial linear momentum transfers inferred from these recoil range distributions were used to identify the evaporation residues formed by complete and incomplete fusion mechanisms. The results indicate the occurrence of incomplete fusion involving the breakup of {sup 20}Ne into {sup 4}He+{sup 16}O and/or {sup 8}Be+{sup 12}C followed by fusion of one of the fragments with target nucleus {sup 165}Ho. Complete and incomplete fusion reaction channels have been identified in the production of various evaporation residues and an attempt has been made to separate out relative contributions of complete and incomplete fusion components from the analysis of the measured recoil range distribution data. The total contribution of complete and incomplete fusion channels has also been estimated.

  12. Chemical Effects in the Separation Process of a Differential Mobility / Mass Spectrometer System

    PubMed Central

    Schneider, Bradley B.; Covey, Thomas R.; Coy, Stephen L.; Krylov, Evgeny V.; Nazarov, Erkinjon G.

    2013-01-01

    In differential mobility spectrometry (DMS, also referred to as high field asymmetric waveform ion mobility spectrometry, FAIMS), ions are separated on the basis of the difference in their mobility under high and low electric fields. The addition of polar modifiers to the gas transporting the ions through a DMS enhances the formation of clusters in a field-dependent way and thus amplifies the high and low field mobility difference resulting in increased peak capacity and separation power. Observations of the increase in mobility field dependence are consistent with a cluster formation model, also referred to as the dynamic cluster-decluster model. The uniqueness of chemical interactions that occur between an ion and cluster-forming neutrals increases the selectivity of the separation and the depression of low-field mobility relative to high-field mobility increases the compensation voltage and peak capacity. The effect of polar modifiers on the peak capacity across a broad range of chemicals has been investigated. We discuss the theoretical underpinnings which explain the observed effects. In contrast to the result from polar modifiers, we find that using mixtures of inert gases as the transport gas improve resolution by reducing peak width but has very little effect on peak capacity or selectivity. Inert gases do not cluster and thus do not reduce low field mobility relative to high-field mobility. The observed changes in the differential mobility α parameter exhibited by different classes of compounds when the transport gas contains polar modifiers or has a significant fraction of inert gas can be explained on the basis of the physical mechanisms involved in the separation processes. PMID:20121077

  13. First spatial separation of a heavy ion isomeric beam with a multiple-reflection time-of-flight mass spectrometer

    NASA Astrophysics Data System (ADS)

    Dickel, T.; Plaß, W. R.; Ayet San Andres, S.; Ebert, J.; Geissel, H.; Haettner, E.; Hornung, C.; Miskun, I.; Pietri, S.; Purushothaman, S.; Reiter, M. P.; Rink, A.-K.; Scheidenberger, C.; Weick, H.; Dendooven, P.; Diwisch, M.; Greiner, F.; Heiße, F.; Knöbel, R.; Lippert, W.; Moore, I. D.; Pohjalainen, I.; Prochazka, A.; Ranjan, M.; Takechi, M.; Winfield, J. S.; Xu, X.

    2015-05-01

    211Po ions in the ground and isomeric states were produced via 238U projectile fragmentation at 1000 MeV/u. The 211Po ions were spatially separated in flight from the primary beam and other reaction products by the fragment separator FRS. The ions were energy-bunched, slowed-down and thermalized in a gas-filled cryogenic stopping cell (CSC). They were then extracted from the CSC and injected into a high-resolution multiple-reflection time-of-flight mass spectrometer (MR-TOF-MS). The excitation energy of the isomer and, for the first time, the isomeric-to-ground state ratio were determined from the measured mass spectrum. In the subsequent experimental step, the isomers were spatially separated from the ions in the ground state by an ion deflector and finally collected with a silicon detector for decay spectroscopy. This pioneering experimental result opens up unique perspectives for isomer-resolved studies. With this versatile experimental method new isomers with half-lives longer than a few milliseconds can be discovered and their decay properties can be measured with highest sensitivity and selectivity. These experiments can be extended to studies with isomeric beams in nuclear reactions.

  14. A gas ionisation detector in the axial (Bragg) geometry used for the time-of-flight elastic recoil detection analysis

    SciTech Connect

    Siketić, Zdravko; Skukan, Natko; Bogdanović Radović, Iva

    2015-08-15

    In this paper, time-of-flight elastic recoil detection analysis spectrometer with a newly constructed gas ionization detector for energy detection is presented. The detector is designed in the axial (Bragg) geometry with a 3 × 3 array of 50 nm thick Si{sub 3}N{sub 4} membranes as an entrance window. 40 mbar isobutane gas was sufficient to stop a 30 MeV primary iodine beam as well as all recoils in the detector volume. Spectrometer and detector performances were determined showing significant improvement in the mass and energy resolution, respectively, comparing to the spectrometer with a standard silicon particle detector for an energy measurement.

  15. Masses and proton separation energies obtained from Q{sub a} and Q{sub p} measurements.

    SciTech Connect

    Davids, C. N.; Woods, P. J.; Batchelder, J. C.; Bingham, C. R.; Blumenthal, D. J.; Brown, L. T.; Carpenter, L. F.; Henderson, D. J.; Janssens, R. V. F.; Penttila, H. T.; Seweryniak, D.

    2000-10-20

    For many nuclei beyond the proton drip line in the Z>72, N>82 region, both proton and a emission are energetically allowed. In the case of some proton emitters, there are {alpha}-decay chains emanating from both parent and daughter nuclei. This means that if the mass excess of one member of an {alpha}-decay chain is known, then the mass excesses for all members of both chains can be obtained. In addition, proton separation energies may be derived for nuclei in the {alpha}-decay chain of the proton emitter. The method of time- and space-correlations also allows the identification of isomeric states in these nuclei. As an example, a large number of mass excesses and proton separation energies for ground and metastable states have been derived from Q{sub a} and Q{sub p} values obtained from the proton emitters {sup 165,166,167}Ir, {sup 171}Au, {sup 177}Tl, and their daughters.

  16. Ion separation in imperfect fields of the quadrupole mass analyzer Part I. Ion beam dynamics in the phase-space

    NASA Astrophysics Data System (ADS)

    Titov, Vladimir V.

    1995-01-01

    The theoretical aspects of ion separation in imperfect fields of the quadrupole mass analyzer are discussed by applying analysis of the beam dynamics in a phase-space. The analytical method which uses an approximate solution of the Hill equation with a small heterogeneous part which indicates that the trap mechanism of ion separation is conditioned by the properties of characteristic solutions is improved. These solutions are reduced to an approximate solution in the form of a general solution of a homogeneous Mathieu equation with combined factors taking into account a small heterogeneous part which defines the region of beam capture (acceptance) in a phase-space. The estimation criterion of simulation accuracy is the relative deviation of an operating point on the Mathieu diagram from the top of a stability triangle. The infringement of independence principle of ion oscillations about each of the positional axes caused by distortions increases the cross-sectional area of the beam. The beam is cut out by the mass analyzer aperture. This causes transmission losses which depend on phase. Therefore, the ion current at the mass analyzer exit is amplitude modulated by the frequency of the alternate component of field. The maximum current is at zero phase. The modulation depth is proportional to the relative value of the distortions.

  17. Determination of the extraction efficiency for 233U source α-recoil ions from the MLL buffer-gas stopping cell

    NASA Astrophysics Data System (ADS)

    v. d. Wense, Lars; Seiferle, Benedict; Laatiaoui, Mustapha; Thirolf, Peter G.

    2015-03-01

    Following the α decay of 233U, 229Th recoil ions are shown to be extracted in a significant amount from the MLL buffer-gas stopping cell. The produced recoil ions and subsequent daughter nuclei are mass purified with the help of a customized quadrupole mass spectrometer. The combined extraction and mass purification efficiency for 229Th3+ is determined via MCP-based measurements and via the direct detection of the 229Th α decay. A large value of (10±2)% for the combined extraction and mass purification efficiency of 229Th3+ is obtained at a mass resolution of about 1u/e. In addition to 229Th, also other α-recoil ions of the 233, 232U decay chains are addressed.

  18. PLANETS AROUND LOW-MASS STARS (PALMS). II. A LOW-MASS COMPANION TO THE YOUNG M DWARF GJ 3629 SEPARATED BY 0.''2

    SciTech Connect

    Bowler, Brendan P.; Liu, Michael C.; Shkolnik, Evgenya L.; Tamura, Motohide

    2012-09-01

    We present the discovery of a 0.''2 companion to the young M dwarf GJ 3629 as part of our high-contrast adaptive optics imaging search for giant planets around low-mass stars with the Keck-II and Subaru telescopes. Two epochs of imaging confirm that the pair is comoving and reveal signs of orbital motion. The primary exhibits saturated X-ray emission which, together with its UV photometry from GALEX, points to an age younger than {approx}300 Myr. At these ages the companion lies below the hydrogen burning limit with a model-dependent mass of 46 {+-} 16 M{sub Jup} based on the system's photometric distance of 22 {+-} 3 pc. Resolved YJHK photometry of the pair indicates a spectral type of M7 {+-} 2 for GJ 3629 B. With a projected separation of 4.4 {+-} 0.6 AU and an estimated orbital period of 21 {+-} 5 yr, GJ 3629 AB is likely to yield a dynamical mass in the next several years, making it one of only a handful of brown dwarfs to have a measured mass and an age constrained from the stellar primary.

  19. A Miniature System for Separating Aerosol Particles and Measuring Mass Concentrations

    PubMed Central

    Liang, Dao; Shih, Wen-Pin; Chen, Chuin-Shan; Dai, Chi-An

    2010-01-01

    We designed and fabricated a new sensing system which consists of two virtual impactors and two quartz-crystal microbalance (QCM) sensors for measuring particle mass concentration and size distribution. The virtual impactors utilized different inertial forces of particles in air flow to classify different particle sizes. They were designed to classify particle diameter, d, into three different ranges: d < 2.28 μm, 2.28 μm ≤ d ≤ 3.20 μm, d > 3.20 μm. The QCM sensors were coated with a hydrogel, which was found to be a reliable adhesive for capturing aerosol particles. The QCM sensor coated with hydrogel was used to measure the mass loading of particles by utilizing its characteristic of resonant frequency shift. An integrated system has been demonstrated. PMID:22319317

  20. Recent advances in enrichment and separation strategies for mass spectrometry-based phosphoproteomics

    PubMed Central

    Yang, Chenxi; Zhong, Xuefei; Li, Lingjun

    2016-01-01

    Due to the significance of protein phosphorylation in various biological processes and signaling events, new analytical techniques for enhanced phosphoproteomics have been rapidly introduced in recent years. The combinatorial use of the phospho-specific enrichment techniques and prefractionation methods prior to MS analysis enables comprehensive profiling of the phosphoproteome and facilitates deciphering the critical roles that phosphorylation plays in signaling pathways in various biological systems. This review places special emphasis on the recent five-year (2009–2013) advances for enrichment and separation techniques that have been utilized for phosphopeptides prior to MS analysis. PMID:24687451

  1. Atom interferometric studies of light scattering - A new technique for measuring atomic recoil

    NASA Astrophysics Data System (ADS)

    Beattie, Scott

    This dissertation presents two techniques for measuring the atomic recoil frequency, oq, using a single-state atom interferometer that utilizes a dilute cloud of laser-cooled 85Rb atoms. An important motivation for these measurements is that o q, which is related to the ratio of Planck's constant and the atomic mass of rubidium hmRb , can be used to infer the atomic fine structure constant, alpha. The two techniques presented here involve time domain measurements carried out with standing-wave laser fields that manipulate atoms in the same atomic ground state and exploit the wave nature of cold atoms. The first technique uses two off-resonant standing-wave pulses to interfere momentum states so that the recoil frequency can be determined. However, to model the signal shape it is necessary to include effects of spontaneous emission during the interaction with light and the spatial profile of the laser beam. The second technique provides a robust alternative approach for measuring the recoil frequency because the signal shape is considerably simpler and can be modeled easily. We report measurements of atomic recoil using both techniques that are precise to ˜ 1 part per million. The precision was limited mainly by the time scale of the experiment (˜ 20 ms) due to the presence of magnetic field gradients. The dissertation also discusses recent improvements that have extended the time scale to the transit time limit for cold atoms. This is the time of travel of cold atoms through the region of interaction defined by the laser beams. The interferometer uses two standing-wave pulses separated by time T to put the atoms in a superposition of momentum states. Interference between momentum states produce a density grating echo signal at time 2 T. The echo time, 2T, corresponds to the time at which the Doppler phases of the momentum states associated with all atoms in the sample cancel. The echo technique is, therefore, a general method to overcome the effect of the

  2. Rapid chiral separation of racemic cetirizine in human plasma using subcritical fluid chromatography-tandem mass spectrometry.

    PubMed

    Eom, Han Young; Kang, Myunghee; Kang, Seung Woo; Kim, Unyong; Suh, Joon Hyuk; Kim, Junghyun; Cho, Hyun-Deok; Jung, Yura; Yang, Dong-Hyug; Han, Sang Beom

    2016-01-01

    A method for fast chiral separation of cetirizine and quantitation of levocetirizine in human plasma using subcritical fluid chromatography with tandem mass spectrometry was developed and validated. The chromatographic separation was performed using a Chiralpak IE column (2.1 mm×150 mm, 5 μm) with an isocratic elution of CO2/organic modifier (55/45, v/v) at a flow rate of 0.85 mL/min. The organic modifier was composed of water/methanol (5/95, v/v). The makeup flow was optimized at water/methanol (10/90, v/v) and 0.2 mL/min. The most influential parameters on the separation of cetirizine affecting resolution, retention time and sensitivity were selected by fractional factorial design. The 3 selected factors were optimized by response surface methodology. Tandem mass spectrometry was used at electrospray ionization, positive ion mode, and multiple-reaction monitoring mode. Isotope-labeled cetirizine-d4 was used as the internal standard. The sample preparation of human plasma was conducted by solid phase extraction of hydrophilic-lipophilic balance (HLB) type. The developed method was validated for selectivity, linearity, precision, accuracy, recovery, limit of quantitation (LOQ), and limit of detection (LOD). The real human plasma samples were analyzed and the pharmacokinetic results were compared with results of previous research. The developed method was found to be reliable based on the similarity between the results of the current and previous methods. The chiral separation for cetirizine and economic feasibility were compared with those of previous studies using normal phase-HPLC or reversed phase-HPLC. The established analytical method could be successfully applied to pharmacokinetic study with reduction in the analysis time and costs. PMID:26440285

  3. Size, separation, structural order, and mass density of molecules packing in water and ice

    PubMed Central

    Huang, Yongli; Zhang, Xi; Ma, Zengsheng; Li, Wen; Zhou, Yichun; Zhou, Ji; Zheng, Weitao; Sun, Chang Q.

    2013-01-01

    The structural symmetry and molecular separation in water and ice remain uncertain. We present herewith a solution to unifying the density, the structure order and symmetry, the size (H-O length dH), and the separation (dOO = dL + dH or the O:H length dL) of molecules packing in water and ice in terms of statistic mean. This solution reconciles: i) the dL and the dH symmetrization of the O:H-O bond in compressed ice, ii) the dOO relaxation of cooling water and ice and, iii) the dOO expansion of a dimer and between molecules at water surface. With any one of the dOO, the density ρ(g·cm−3), the dL, and the dH, as a known input, one can resolve the rest quantities using this solution that is probing conditions or methods independent. We clarified that: i) liquid water prefers statistically the mono-phase of tetrahedrally-coordinated structure with fluctuation, ii) the low-density phase (supersolid phase as it is strongly polarized with even lower density) exists only in regions consisting molecules with fewer than four neighbors and, iii) repulsion between electron pairs on adjacent oxygen atoms dictates the cooperative relaxation of the segmented O:H-O bond, which is responsible for the performance of water and ice. PMID:24141643

  4. Control of Chemical Effects in the Separation Process of a Differential Mobility / Mass Spectrometer System

    PubMed Central

    Schneider, Bradley B.; Coy, Stephen L.; Krylov, Evgeny V.; Nazarov, Erkinjon G.

    2013-01-01

    Differential mobility spectrometry (DMS) separates ions on the basis of the difference in their migration rates under high versus low electric fields. Several models describing the physical nature of this field mobility dependence have been proposed but emerging as a dominant effect is the clusterization model sometimes referred to as the dynamic cluster-decluster model. DMS resolution and peak capacity is strongly influenced by the addition of modifiers which results in the formation and dissociation of clusters. This process increases selectivity due to the unique chemical interactions that occur between an ion and neutral gas phase molecules. It is thus imperative to bring the parameters influencing the chemical interactions under control and find ways to exploit them in order to improve the analytical utility of the device. In this paper we describe three important areas that need consideration in order to stabilize and capitalize on the chemical processes that dominate a DMS separation. The first involves means of controlling the dynamic equilibrium of the clustering reactions with high concentrations of specific reagents. The second area involves a means to deal with the unwanted heterogeneous cluster ion populations emitted from the electrospray ionization process that degrade resolution and sensitivity. The third involves fine control of parameters that affect the fundamental collision processes, temperature and pressure. PMID:20065515

  5. Nuclear Recoil Effect in the Lamb Shift of Light Hydrogenlike Atoms

    NASA Astrophysics Data System (ADS)

    Yerokhin, V. A.; Shabaev, V. M.

    2015-12-01

    We report high-precision calculations of the nuclear recoil effect to the Lamb shift of hydrogenlike atoms to the first order in the electron-nucleus mass ratio and to all orders in the nuclear binding strength parameter Z α . The results are in excellent agreement with the known terms of the Z α expansion and allow an accurate identification of the nonperturbative higher-order remainder. For hydrogen, the higher-order remainder was found to be much larger than anticipated. This result resolves the long-standing disagreement between the numerical all-order and analytical Z α -expansion approaches to the recoil effect and completely removes the second-largest theoretical uncertainty in the hydrogen Lamb shift of the 1 S and 2 S states.

  6. A gun recoil system employing a magnetorheological fluid damper

    NASA Astrophysics Data System (ADS)

    Li, Z. C.; Wang, J.

    2012-10-01

    This research aims to design and control a full scale gun recoil buffering system which works under real firing impact loading conditions. A conventional gun recoil absorber is replaced with a controllable magnetorheological (MR) fluid damper. Through dynamic analysis of the gun recoil system, a theoretical model for optimal design and control of the MR fluid damper for impact loadings is derived. The optimal displacement, velocity and optimal design rules are obtained. By applying the optimal design theory to protect against impact loadings, an MR fluid damper for a full scale gun recoil system is designed and manufactured. An experimental study is carried out on a firing test rig which consists of a 30 mm caliber, multi-action automatic gun with an MR damper mounted to the fixed base through a sliding guide. Experimental buffering results under passive control and optimal control are obtained. By comparison, optimal control is better than passive control, because it produces smaller variation in the recoil force while achieving less displacement of the recoil body. The optimal control strategy presented in this paper is open-loop with no feedback system needed. This means that the control process is sensor-free. This is a great benefit for a buffering system under impact loading, especially for a gun recoil system which usually works in a harsh environment.

  7. Searching for Scatterers: High-Contrast Imaging of Young Stars Hosting Wide-Separation Planetary-Mass Companions

    NASA Astrophysics Data System (ADS)

    Bryan, Marta L.; Bowler, Brendan P.; Knutson, Heather A.; Kraus, Adam L.; Hinkley, Sasha; Mawet, Dimitri; Nielsen, Eric L.; Blunt, Sarah C.

    2016-08-01

    We have conducted an angular differential imaging survey with NIRC2 at Keck in search of close-in substellar companions to a sample of seven systems with confirmed planetary-mass companions (PMCs) on wide orbits (>50 au). These wide-separation PMCs pose significant challenges to all three possible formation mechanisms: core accretion plus scattering, disk instability, and turbulent fragmentation. We explore the possibility that these companions formed closer in and were scattered out to their present-day locations by searching for other massive bodies at smaller separations. The typical sensitivity for this survey is ΔK ∼ 12.5 at 1″. We identify eight candidate companions, whose masses would reach as low as one Jupiter mass if gravitationally bound. From our multi-epoch astrometry we determine that seven of these are conclusively background objects, while the eighth near DH Tau is ambiguous and requires additional monitoring. We rule out the presence of >7 M Jup bodies in these systems down to 15–50 au that could be responsible for scattering. This result combined with the totality of evidence suggests that dynamical scattering is unlikely to have produced this population of PMCs. We detect orbital motion from the companions ROXs 42B b and ROXs 12 b, and from this determine 95% upper limits on the companions’ eccentricities of 0.58 and 0.83 respectively. Finally, we find that the 95% upper limit on the occurrence rate of additional planets with masses between 5 and 15 M Jup outside of 40 au in systems with PMCs is 54%.

  8. Application of combined mass spectrometry and partial amino acid sequence to the identification of gel-separated proteins.

    PubMed

    Patterson, S D; Thomas, D; Bradshaw, R A

    1996-05-01

    The combined use of peptide mass information with amino acid sequence information derived by chemical sequencing or mass spectrometry (MS)-based approaches provides a powerful means of protein identification. We have used a two-part strategy to identify proteins from nerve growth factor (NGF)-stimulated rat adrenal pheochromocytoma cell line PC-12 cell lysates that associate with the adaptor protein Shc (Shc homologous and collagen protein). Initial experiments with metabolically radiolabeled cell extracts separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) revealed a number of proteins that coimmunoprecipitated with anti-Shc antibody compared with control (unstimulated) cell extracts. The experiment was scaled up and cell lysate from NGF-stimulated PC-12 cells was applied to a glutathione-S-transferase (GST)-Shc affinity column, eluted, separated by SDS-PAGE and blotted to Immobilon-CD. The blotted proteins were proteolytically digested in situ, and the masses obtained from the extracted peptides were used in a peptide-mass search program in an attempt to identify the protein. Even if a strong candidate was found using this search, an additional step was performed to confirm the identification. The mixtures were fractionated by reversed-phase high-performance liquid chromatography (RP-HPLC) and subjected to chemical sequencing to obtain (partial) sequence information, or post-source decay (PSD-) matrix-assisted laser-desorption ionization (MALDI)-MS to obtain sequence-specific fragment ions. This data was used in a peptide-sequence tag search to confirm the identity of the proteins. This combined approach allowed identification of four proteins of M(r) 43,000 to 200,000. In one case the identified protein clearly did not correspond to the radiolabeled band, but to a protein contaminant from the column. The advantages and pitfalls of the approach are discussed. PMID:8783013

  9. Searching for Scatterers: High-Contrast Imaging of Young Stars Hosting Wide-Separation Planetary-Mass Companions

    NASA Astrophysics Data System (ADS)

    Bryan, Marta L.; Bowler, Brendan P.; Knutson, Heather A.; Kraus, Adam L.; Hinkley, Sasha; Mawet, Dimitri; Nielsen, Eric L.; Blunt, Sarah C.

    2016-08-01

    We have conducted an angular differential imaging survey with NIRC2 at Keck in search of close-in substellar companions to a sample of seven systems with confirmed planetary-mass companions (PMCs) on wide orbits (>50 au). These wide-separation PMCs pose significant challenges to all three possible formation mechanisms: core accretion plus scattering, disk instability, and turbulent fragmentation. We explore the possibility that these companions formed closer in and were scattered out to their present-day locations by searching for other massive bodies at smaller separations. The typical sensitivity for this survey is ΔK ˜ 12.5 at 1″. We identify eight candidate companions, whose masses would reach as low as one Jupiter mass if gravitationally bound. From our multi-epoch astrometry we determine that seven of these are conclusively background objects, while the eighth near DH Tau is ambiguous and requires additional monitoring. We rule out the presence of >7 M Jup bodies in these systems down to 15–50 au that could be responsible for scattering. This result combined with the totality of evidence suggests that dynamical scattering is unlikely to have produced this population of PMCs. We detect orbital motion from the companions ROXs 42B b and ROXs 12 b, and from this determine 95% upper limits on the companions’ eccentricities of 0.58 and 0.83 respectively. Finally, we find that the 95% upper limit on the occurrence rate of additional planets with masses between 5 and 15 M Jup outside of 40 au in systems with PMCs is 54%.

  10. Electrophoretic separation techniques and their hyphenation to mass spectrometry in biological inorganic chemistry.

    PubMed

    Holtkamp, Hannah; Grabmann, Gerlinde; Hartinger, Christian G

    2016-04-01

    Electrophoretic methods have been widely applied in research on the roles of metal complexes in biological systems. In particular, CE, often hyphenated to a sensitive MS detector, has provided valuable information on the modes of action of metal-based pharmaceuticals, and more recently new methods have been added to the electrophoretic toolbox. The range of applications continues to expand as a result of enhanced CE-to-MS interfacing, with sensitivity often at picomolar level, and evolved separation modes allowing for innovative sample analysis. This article is a followup to previous reviews about CE methods in metallodrug research (Electrophoresis, 2003, 24, 2023-2037; Electrophoresis, 2007, 28, 3436-3446; Electrophoresis, 2012, 33, 622-634), also providing a comprehensive overview of metal species studied by electrophoretic methods hyphenated to MS. It highlights the latest CE developments, takes a sneak peek into gel electrophoresis, traces biomolecule labeling, and focuses on the importance of early-stage drug development. PMID:26643265

  11. Kinematically Identified Recoiling Supermassive Black Hole Candidates in SDSS QSOs with z > 0.25

    NASA Astrophysics Data System (ADS)

    Kim, D.-C.; Evans, A. S.; Stierwalt, S.; Privon, G. C.

    2016-06-01

    We have performed a spectral decomposition to search for recoiling supermassive black holes (rSMBHs) in Sloan Digital Sky Survey (SDSS) quasi-stellar objects (QSOs) with z < 0.25. Out of 1271 QSOs, we have identified 26 rSMBH candidates that are recoiling toward us. The projected recoil velocities range from ‑76 to ‑307 km s‑1 with a mean of ‑149 ± 58 km s‑1. Most of the rSMBH candidates are hosted by gas-rich luminous infrared galaxies (LIRGs)/ultra-luminous infrared galaxies (ULIRGs), but only 23% of them show signs of tidal features, which suggests that a majority of them are advanced mergers. We find that the black hole masses M BH of the rSMBH candidates are on average ∼5 times smaller than those of their stationary counterparts and cause a scatter in the {M}{BH}-{σ }\\ast relation. The Eddington ratios of all of the rSMBH candidates are larger than 0.1, with a mean of 0.52 ± 0.27, suggesting that they are actively accreting mass. Velocity shifts in high-excitation coronal lines suggest that the rSMBH candidates are recoiling with an average velocity of about ‑265 km s‑1. The electron density in the narrow line region of the H ii rSMBH candidates is about 1/10 of that in active galactic nucleus (AGN) rSMBH candidates, probably because the AGN in the former was more spatially offset than that in the latter. The estimated spatial offsets between the rSMBH candidate and the center of the host galaxy range from 0.″21 to 1.″97 and need to be confirmed spatially with high-resolution adaptive optics imaging observations.

  12. Enantiomeric separation in comprehensive two-dimensional gas chromatography with accurate mass analysis.

    PubMed

    Chin, Sung-Tong; Nolvachai, Yada; Marriott, Philip J

    2014-11-01

    Chiral comprehensive two-dimensional gas chromatography (eGC×GC) coupled to quadrupole-accurate mass time-of-flight mass spectrometry (QTOFMS) was evaluated for its capability to report the chiral composition of several monoterpenes, namely, α-pinene, β-pinene, and limonene in cardamom oil. Enantiomers in a standard mixture were fully resolved by direct enantiomeric-GC analysis with a 2,3-di-O-methyl-6-t-butylsilyl derivatized β-cyclodextrin phase; however, the (+)-(R)-limonene enantiomer in cardamom oil was overlapped with other background components including cymene and cineole. Verification of (+)-(R)-limonene components based on characteristic ions at m/z 136, 121, and 107 acquired by chiral single-dimension GC-QTOFMS in the alternate MS/MSMS mode of operation was unsuccessful due to similar parent/daughter ions generated by interfering or co-eluting cymene and cineole. Column phases SUPELCOWAX, SLB-IL111, HP-88, and SLB-IL59, were incorporated as the second dimension column ((2)D) in chiral GC×GC analysis; the SLB-IL59 offered the best resolution for the tested monoterpene enantiomers from the matrix background. Enantiomeric ratios for α-pinene, β-pinene, and limonene were determined to be 1.325, 2.703, and 1.040, respectively, in the cardamom oil sample based on relative peak area data. PMID:24420979

  13. Separation and identification of oligomeric phenylethoxysiloxanols by liquid chromatography-electrospray ionization mass spectrometry.

    PubMed

    Jiang, Yuting; Wan, Qian-Hong

    2015-05-15

    Liquid chromatography-electrospray ionization mass spectrometry has been applied to qualitative analysis of oligomeric phenylethoxysiloxanols, a class of organosilanols as active intermediates to polyhedral silsesquioxanes. The phenylethoxysiloxanol samples were prepared by controlled acid-catalyzed hydrolysis and condensation of phenyltriethoxysilane at various molar equivalents of water (r1) and characterized by standard spectroscopic techniques. Using a gradient binary water-methanol mobile phase, these reaction products were resolved on octadecylsiloxane silica stationary phase and subsequently identified by online electrospray ionization mass spectrometric detection. Results show that the reaction products are composed of a multitude of linear and monocyclic siloxanol oligomers with various numbers of silicon atoms and hydroxyl groups, depending upon the reaction conditions used. With the r1 value increasing from 0.5 to 2.0, the chain lengths of the oligomers increase slightly but the numbers of hydroxyl groups increase considerably, accompanying by structural evolution from chains to rings. Characterization of the retention behavior of these oligomers indicates that hydrophobic interactions of phenyl and ethoxy groups with the stationary phase are responsible for their retention in reversed-phase liquid chromatography. PMID:25843423

  14. Difference between a Photon's Momentum and an Atom's Recoil

    SciTech Connect

    Gibble, Kurt

    2006-08-18

    When an atom absorbs a photon from a laser beam that is not an infinite plane wave, the atom's recoil is less than ({Dirac_h}/2{pi})k in the propagation direction. We show that the recoils in the transverse directions produce a lensing of the atomic wave functions, which leads to a frequency shift that is not discrete but varies linearly with the field amplitude and strongly depends on the atomic state detection. The same lensing effect is also important for microwave atomic clocks. The frequency shifts are of the order of the naive recoil shift for the transverse wave vector of the photons.

  15. Ricin as a weapon of mass terror--separating fact from fiction.

    PubMed

    Schep, Leo J; Temple, Wayne A; Butt, Grant A; Beasley, Michael D

    2009-11-01

    In recent years there has been an increased concern regarding the potential use of chemical and biological weapons for mass urban terror. In particular, there are concerns that ricin could be employed as such an agent. This has been reinforced by recent high profile cases involving ricin, and its use during the cold war to assassinate a high profile communist dissident. Nevertheless, despite these events, does it deserve such a reputation? Ricin is clearly toxic, though its level of risk depends on the route of entry. By ingestion, the pathology of ricin is largely restricted to the gastrointestinal tract where it may cause mucosal injuries; with appropriate treatment, most patients will make a full recovery. As an agent of terror, it could be used to contaminate an urban water supply, with the intent of causing lethality in a large urban population. However, a substantial mass of pure ricin powder would be required. Such an exercise would be impossible to achieve covertly and would not guarantee success due to variables such as reticulation management, chlorination, mixing, bacterial degradation and ultra-violet light. By injection, ricin is lethal; however, while parenteral delivery is an ideal route for assassination, it is not realistic for an urban population. Dermal absorption of ricin has not been demonstrated. Ricin is also lethal by inhalation. Low doses can lead to progressive and diffuse pulmonary oedema with associated inflammation and necrosis of the alveolar pneumocytes. However, the risk of toxicity is dependent on the aerodynamic equivalent diameter (AED) of the ricin particles. The AED, which is an indicator of the aerodynamic behaviour of a particle, must be of sufficiently low micron size as to target the human alveoli and thereby cause major toxic effects. To target a large population would also necessitate a quantity of powder in excess of several metric tons. The technical and logistical skills required to formulate such a mass of powder to

  16. Application of mass-separated focused ion beams in nano-technology

    NASA Astrophysics Data System (ADS)

    Bischoff, L.

    2008-04-01

    FIB applications like writing ion implantation, ion beam mixing or ion beam synthesis in the μm- or nm range often require ion species other than gallium. Therefore alloy liquid metal ion sources (LMIS) have to be developed and applied in FIB tools. The energy distribution of ions emitted from an alloy LMIS is one of the crucial parameters for the performance of a FIB column. Different source materials like AuGe, AuSi, AuGeSi, CoNd, ErNi, ErFeNiCr, MnGe, GaBi, GaBiLi, SnPb, … were investigated with respect to the energy spread of the different ion species as a function of emission current, ion mass and emitter temperature. Different alloy LMIS's have been developed and used in the FZD - FIB system especially for writing implantation to fabricate sub-μm pattern without any lithographic steps. Co and various other ion species were applied to generate CoSi2 nano-structures, like dots and wires by ion beam synthesis or to manipulate the properties of magnetic films. Additionally, the possibility of varying the flux in the FIB by changing the pixel dwell-time can be used for the investigation of the radiation damage and dynamic annealing in Si, Ge and SiC at elevated implantation temperatures. Furthermore, a broad spectrum of ions was employed to study in a fast manner the sputtering process depending on temperature, angle of incidence and ion mass on a couple of target materials. These studies are important for the 3D-fabrication of various kinds of micro-tools by FIB milling.

  17. Design of a single magnet separator with mass resolving power m/Δm ≈/20,000

    NASA Astrophysics Data System (ADS)

    Breitenfeldt, Martin; Augustin, Mathieu; Catherall, Richard; Giles, Tim; Schoerling, Daniel; Tveten, Gry M.

    2016-06-01

    ISOLDE at CERN is a leading radioactive ion beam facility. With its upgrade, the HIE-ISOLDE project, an increase in primary beam intensity and energy is envisaged and the aim is a significant increase in intensity of the exotic beams. The high resolution separator (HRS) after the upgrade is required to suppress contaminations almost completely when the masses differ to the beam of interest by Δm / m > 1 / 20, 000 . Here a 120° magnet with a bending radius of 1.25 m has been chosen. The magnetic rigidity is 0.625 Tm (B-field of 0.5 T) to allow for separation of molecules of up to a mass of 300 u. The magnet comprises a yoke in wedged H-type configuration for stability and precision and pole face conductors for focusing and compensation of aberrations. The concept was derived analytically, refined with the OPERA 2D software and tested with the ray-tracing module of OPERA 3D.

  18. Identification by mass spectrometry of two-dimensional gel electrophoresis-separated proteins extracted from lager brewing yeast.

    PubMed

    Joubert, R; Strub, J M; Zugmeyer, S; Kobi, D; Carte, N; Van Dorsselaer, A; Boucherie, H; Jaquet-Guffreund, L

    2001-08-01

    As two-dimensional (2-D) electrophoresis allows the separation of several hundred proteins in a single gel, this technique has become an important tool for proteome studies and for investigating the cellular physiology. In order to take advantage of information provided by the comparison of proteome pictures, the mass spectrometry technique is the way chosen for a rapid and an accurate identification of proteins of interest. Unfortunately, in the case of industrial yeasts, due to the high level of complexity of their genome, the whole DNA sequence is not yet available and all encoded protein sequences are still unknown. Nevertheless, this study presents here 30 lager brewing yeast proteins newly identified with matrix assisted laser desorption/ionization-time of flight (MALDI-TOF), tandem mass spectrometry (MS/MS) and database searching against the protein sequences of Saccharomyces cerevisiae. The identified proteins of the industrial strain correspond to proteins which do not comigrate with known proteins of S. cerevisiae separated on 2-D gels. This study presents an application of the MS technique for the identification of industrial yeast proteins which are only homologous to the corresponding S. cerevisiae proteins. PMID:11565791

  19. Determination of heavy metals by inductively coupled plasma mass spectrometry after on-line separation and preconcentration

    NASA Astrophysics Data System (ADS)

    Dressler, Valderi L.; Pozebon, Dirce; Curtius, Adilson J.

    1998-10-01

    A method for the determination of Cu, As, Se, Cd, In, Hg, Tl, Pb and Bi in waters and in biological materials by inductively coupled plasma mass spectrometry, after an on-line separation, is described. The matrix separation and analyte preconcentration is accomplished by retention of the analytes complexed with the ammonium salt of O,O-diethyl dithiophosphoric acid in a HNO 3 solution on C 18 immobilized on silica in a minicolumn. Methanol, as eluent, is introduced in the conventional pneumatic nebulizer of the instrument. In order to use the best compromise conditions, concerning the ligand and acid concentrations, the analytes were determined in two separate groups. The enrichment factors were in the range from 5 to 61, depending on the analyte. The limits of detection varied from 0.43 ng L -1 for Bi to 33 ng L -1 for Cu. The sample consumption is only 2.3 mL for each group and the sampling frequency is 21 h -1. The accuracy was tested by analysing five certified reference materials: water, riverine water, urine, bovine muscle and bovine liver. The agreement between obtained and certified concentrations was very good, except for As. The relatively small volume of methanol, used as eluent, minimizes the problems produced by the introduction of organic solvent into the plasma.

  20. Exerpts from the history of alpha recoils.

    PubMed

    Samuelsson, Christer

    2011-05-01

    Any confined air volume holding radon ((222)Rn) gas bears a memory of past radon concentrations due to (210)Pb (T(1/2) = 22 y) and its progenies entrapped in all solid objects in the volume. The efforts of quantifying past radon exposures by means of the left-behind long-lived radon progenies started in 1987 with this author's unsuccessful trials of removing (214)Po from radon exposed glass objects. In this contribution the history and different techniques of assessing radon exposure to man in retrospect will be overviewed. The main focus will be on the implantation of alpha recoils into glass surfaces, but also potential traps in radon dwellings will be discussed. It is concluded that for a successful retrospective application, three crucial imperatives must be met, i.e. firstly, the object must persistently store a certain fraction of the created (210)Pb atoms, secondly, be resistant over decades towards disturbances from the outside and thirdly, all (210)Pb atoms analysed must originate from airborne radon only. For large-scale radon epidemiological studies, non-destructive and inexpensive measurement techniques are essential. Large-scale studies cannot be based on objects rarely found in dwellings or not available for measurements. PMID:21306801

  1. First Measurement of Beam-Recoil Observables Cx and Cz

    SciTech Connect

    R. Bradford; R.A. Schumacher; G. Adams; M.J. Amaryan; P. Ambrozewicz; E. Anciant; M. Anghinolfi; B. Asavapibhop; G. Asryan; G. Audit; H. Avakian; H. Bagdasaryan; N. Baillie; J.P. Ball; N.A. Baltzell; S. Barrow; V. Batourine; M. Battaglieri; K. Beard; I. Bedlinskiy; M. Bektasoglu; M. Bellis; N. Benmouna; B.L. Berman; N. Bianchi; A.S. Biselli; B.E. Bonner; S. Bouchigny; S. Boiarinov; D. Branford; W.J. Briscoe; W.K. Brooks; S. B¨ultmann; V.D. Burkert; C. Butuceanu; J.R. Calarco; S.L. Careccia; D.S. Carman; B. Carnahan; S. Chen; P.L. Cole; A. Coleman; P. Collins; P. Coltharp; D. Cords; † P. Corvisiero; D. Crabb; H. Crannell; V. Crede; J.P. Cummings; R. De Masi; E. De Sanctis; R. De Vita; P.V. Degtyarenko; H. Denizli; L. Dennis; A. Deur; K.V. Dharmawardane; R. Dickson; C. Djalali; G.E. Dodge; J. Donnelly; D. Doughty; P. Dragovitsch; M. Dugger; S. Dytman; O.P. Dzyubak; H. Egiyan; K.S. Egiyan; L. El Fassi; L. Elouadrhiri; A. Empl; P. Eugenio; R. Fatemi; G. Fedotov; G. Feldman; R.J. Feuerbach; T.A. Forest; H. Funsten; M. Garcon; G. Gavalian; G.P. Gilfoyle; K.L. Giovanetti; F.X. Girod; J.T. Goetz; A. Gonenc; R.W. Gothe; K.A. Griffioen; M. Guidal; M. Guillo; N. Guler; L. Guo; V. Gyurjyan; C. Hadjidakis; K. Hafidi; H. Hakobyan; R.S. Hakobyan; J. Hardie; D. Heddle; F.W. Hersman; K. Hicks; I. Hleiqawi; M. Holtrop; J. Hu; M. Huertas; C.E. Hyde-Wright; Y. Ilieva; D.G. Ireland; B.S. Ishkhanov; E.L. Isupov; M.M. Ito; D. Jenkins; H.S. Jo; K. Joo; H.G. Juengst; N. Kalantarians; J.D. Kellie; M. Khandaker; K.Y. Kim; K. Kim; W. Kim; A. Klein; F.J. Klein; M. Klusman; M. Kossov; L.H. Kramer; V. Kubarovsky; J. Kuhn; S.E. Kuhn; S.V. Kuleshov; J. Lachniet; J.M. Laget; J. Langheinrich; D. Lawrence; A.C.S. Lima; K. Livingston; H.Y. Lu; K. Lukashin; M. MacCormick; J.J. Manak; C. Marchand; N. Markov; S. McAleer; B. McKinnon; J.W.C. McNabb; B.A. Mecking; M.D. Mestayer; C.A. Meyer; T. Mibe; K. Mikhailov; M. Mirazita; R. Miskimen; V. Mokeev; K. Moriya; S.A. Morrow; M. Moteabbed; V. Muccifora; J. Mueller; G.S. Mutchler; P. Nadel-Turonski; J. Napolitano; R. Nasseripour; N. Natasha; S. Niccolai; G. Niculescu; I. Niculescu; B.B. Niczyporuk; M.R. Niroula; R.A. Niyazov; M. Nozar; G.V. O’Rielly; M. Osipenko; A.I. Ostrovidov; K. Park; E. Pasyuk; C. Paterson; S.A. Philips; J. Pierce; N. Pivnyuk; D. Pocanic; O. Pogorelko; E. Polli; I. Popa; S. Pozdniakov; B.M. Preedom; J.W. Price; Y. Prok; D. Protopopescu; L.M. Qin; B.P. Quinn; B.A. Raue; G. Riccardi; G. Ricco; M. Ripani; B.G. Ritchie; F. Ronchetti; G. Rosner; P. Rossi; D. Rowntree; P.D. Rubin; F. Sabatie; J. Salamanca; C. Salgado; J.P. Santoro; V. Sapunenko; V.S. Serov; A. Shafi; Y.G. Sharabian; J. Shaw; N.V. Shvedunov; S. Simionatto; A.V. Skabelin; E.S. Smith; L.C. Smith; D.I. Sober; D. Sokhan; M. Spraker; A. Stavinsky; S.S. Stepanyan; S. Stepanyan; B.E. Stokes; P. Stoler; I.I. Strakovsky; S. Strauch; M. Taiuti; S. Taylor; D.J. Tedeschi; U. Thoma; R. Thompson; A. Tkabladze; S. Tkachenko; L. Todor; C. Tur; M. Ungaro; M.F. Vineyard; A.V. Vlassov; K. Wang; D.P. Watts; L.B. Weinstein; H. Weller; D.P. Weygand; M. Williams; E. Wolin; M.H. Wood; A. Yegneswaran; J. Yun; L. Zana; J. Zhang; B. Zhao; and Z.W. Zhao

    2007-03-01

    Spin transfer from circularly polarized real photons to recoiling hyperons has been measured for the reactions $\\vec\\gamma + p \\to K^+ + \\vec\\Lambda$ and $\\vec\\gamma + p \\to K^+ + \\vec\\Sigma^0$. The data were obtained using the CLAS detector at Jefferson Lab for center-of-mass energies $W$ between 1.6 and 2.53 GeV, and for $-0.85<\\cos\\theta_{K^+}^{c.m.}< +0.95$. For the $\\Lambda$, the polarization transfer coefficient along the photon momentum axis, $C_z$, was found to be near unity for a wide range of energy and kaon production angles. The associated transverse polarization coefficient, $C_x$, is smaller than $C_z$ by a roughly constant difference of unity. Most significantly, the {\\it total} $\\Lambda$ polarization vector, including the induced polarization $P$, has magnitude consistent with unity at all measured energies and production angles when the beam is fully polarized. For the $\\Sigma^0$ this simple phenomenology does not hold. All existing hadrodynamic models are in poor agreement with these results.

  2. Scintillation Efficiency of Liquid Xenon for Low Energy Nuclear Recoils

    NASA Astrophysics Data System (ADS)

    Wongjirad, Taritree; Ni, Kaixuan; Manzur, Angel; Kastens, Louis; McKinsey, Daniel

    2008-04-01

    In early 2006, the XENON and ZEPLIN collaborations announced highly stringent upper limits on the WIMP-nucleon cross-section. However, the dominant systematic uncertainty in these limits is due to the uncertainty in the nuclear recoil scintillation efficiency (NRSE) for liquid xenon. The NRSE is defined as the amount of scintillation produced by nuclear recoils, divided by the amount of scintillation produced by electron recoils, per unit energy. Though the NRSE has been measured by several groups, its value at the low energies most important for the liquid xenon WIMP searches has a large uncertainty. Furthermore, the NRSE may vary with the strength of the electric field in the liquid xenon. In an attempt to reduce these uncertainties, we have measured the NRSE down to 5 keV nuclear recoil energy for various electric fields.

  3. INVESTIGATION OF THE FORMATION AND SEPARATION OF AN EXTREME-ULTRAVIOLET WAVE FROM THE EXPANSION OF A CORONAL MASS EJECTION

    SciTech Connect

    Cheng, X.; Ding, M. D.; Zhang, J.; Olmedo, O.; Vourlidas, A.; Liu, Y. E-mail: jzhang7@gmu.edu

    2012-01-20

    We address the nature of EUV waves through direct observations of the formation of a diffuse wave driven by the expansion of a coronal mass ejection (CME) and its subsequent separation from the CME front. The wave and the CME on 2011 June 7 were well observed by the Atmospheric Imaging Assembly on board the Solar Dynamics Observatory. Following the solar eruption onset, marked by the beginning of the rapid increasing of the CME velocity and the X-ray flux of accompanying flare, the CME exhibits a strong lateral expansion. During this impulsive expansion phase, the expansion speed of the CME bubble increases from 100 km s{sup -1} to 450 km s{sup -1} in only six minutes. An important finding is that a diffuse wave front starts to separate from the front of the expanding bubble shortly after the lateral expansion slows down. Also a type II burst is formed near the time of the separation. After the separation, two distinct fronts propagate with different kinematic properties. The diffuse front travels across the entire solar disk, while the sharp front rises up, forming the CME ejecta with the diffuse front ahead of it. These observations suggest that the previously termed EUV wave is a composite phenomenon and driven by the CME expansion. While the CME expansion is accelerating, the wave front is cospatial with the CME front, thus the two fronts are indiscernible. Following the end of the acceleration phase, the wave moves away from the CME front with a gradually increasing distance between them.

  4. Simultaneous separation and determination of organic acids in blueberry juices by capillary electrophoresis- electrospray ionization mass spectrometry.

    PubMed

    Li, Bin; Yongku, Li; Wang, Xinyi; Wang, Fen; Wang, Xu; Wang, Yanfang; Meng, Xianjun

    2015-08-01

    A sensitive and expeditious capillary electrophoresis-electrospray ionization mass spectrometry(CE-ESIMS) method for the separation, identification and determination of succinic, citric, salicylic, malic, benzoic, sorbic, ascorbic, and tartaric acid in blueberry juices has been developed. In order to obtain the analytical separation, CE-MS interface parameters(e.g., buffer pH and composition, sheath liquid and gas flow rates, sheath liquid composition, electrospray voltage, etc.) were carefully optimized. Eight organic acids were baseline separated in 8 min under optimum experimental conditions. The precisions for eight replicate separations of a standard mixture solution were 2.54-4.12 % for peak area and 0.85-2.12 % for migration time respectively. The linear ranges were 10.0-1000.0, 8.0-1000.0, 13.0-1000.0, 6.0-1000.0, 9.0-1000.0, 3.2-600.0, 6.0-1000.0 and 18.0-1000.0 μg/L for succinic, citric, salicylic, malic, benzoic, sorbic, ascorbic, and tartaric acid with detection limits of 2.5, 2.0, 3.4, 1.5, 2.2, 0.8, 1.5, 4.5 μg/L, respectively. The average recoveries of the eight components were between 86.8 and 99.8 % with RSDs of 1.8-5.3 %. The proposed method was applied to the simultaneous analysis of eight analytes in Blueberry Juice samples with satisfactory results. PMID:26243946

  5. A microchip electrophoresis-mass spectrometric platform for fast separation and identification of enantiomers employing the partial filling technique

    PubMed Central

    Li, Xiangtang; Xiao, Dan; Ou, Xiao-Ming; McCullumn, Cassandra; Liu, Yi-Ming

    2013-01-01

    A microchip electrophoresis-mass spectrometric (MCE-MS) method was developed for fast chiral analysis. The proposed MCE-MS platform deployed a glass /PDMS hybrid microchip with an easy-to-fabricate monolithic nanoelectrospray emitter. Enantiomeric MCE separation was achieved by means of the partial filling technique. A novel chip design with an arm channel connecting to the middle of the MCE separation channel for delivering the chiral selector was tested and proven valid. Enantiomeric separation of 3.4-dihydroxyphenylalanine (DOPA), glutamic acid (Glu), and serine (Ser), the selected test compounds, were achieved within 130 s with resolution values (Rs) of 2.4, 1.1, and 1.0, respectively. The proposed chiral MCE-MS assay was sensitive and had detection limits of 43 nM for L-DOPA and 47 nM for D-DOPA. The analytical platform was well suited for studies of stereochemical preference in living cells because it integrated cell culture, sample injection, chiral separation, and MS detection into a single platform. Metabolism of DOPA in human SH-SY5Y neuronal cells was studied as a model system. On-chip incubation of SH-SY5Y cells with racemic DOPA was carried out, and the incubation solution was injected and in-line assayed at time intervals. It was found that L-DOPA concentration decreased gradually as incubation time increased while the concentration of coexisting D-DOPA remained constant. The results firmly indicated that SH-SY5Y cells metabolized L-DOPA effectively while left D-DOPA intact. PMID:24354006

  6. Enhancing Biological Analyses with Three Dimensional Field Asymmetric Ion Mobility, Low Field Drift Time Ion Mobility and Mass Spectrometry (µFAIMS/IMS-MS) Separations

    SciTech Connect

    Zhang, Xing; Ibrahim, Yehia M.; Chen, Tsung-Chi; Kyle, Jennifer E.; Norheim, Randolph V.; Monroe, Matthew E.; Smith, Richard D.; Baker, Erin Shammel

    2015-06-30

    We report the first evaluation of a platform coupling a high speed field asymmetric ion mobility spectrometry microchip (µFAIMS) with drift tube ion mobility and mass spectrometry (IMS-MS). The µFAIMS/IMS-MS platform was used to analyze biological samples and simultaneously acquire multidimensional information of detected features from the measured FAIMS compensation fields and IMS drift times, while also obtaining accurate ion masses. These separations thereby increase the overall separation power, resulting increased information content, and provide more complete characterization of more complex samples. The separation conditions were optimized for sensitivity and resolving power by the selection of gas compositions and pressures in the FAIMS and IMS separation stages. The resulting performance provided three dimensional separations, benefitting both broad complex mixture studies and targeted analyses by e.g. improving isomeric separations and allowing detection of species obscured by “chemical noise” and other interfering peaks.

  7. Recoil splitting of x-ray-induced optical fluorescence

    SciTech Connect

    Gavrilyuk, S.; Aagren, H.; Gel'mukhanov, F.; Sun, Y.-P.; Levin, S.

    2010-03-15

    We show that the anisotropy of the recoil velocity distribution of x-ray-ionized atoms or molecules leads to observable splittings in subsequent optical fluorescence or absorption when the polarization vector of the x rays is parallel to the momentum of the fluorescent photons. The order of the magnitude of the recoil-induced splitting is about 10 {mu}eV, which can be observed using Fourier or laser-absorption spectroscopic techniques.

  8. SIMULATIONS OF RECOILING MASSIVE BLACK HOLES IN THE VIA LACTEA HALO

    SciTech Connect

    Guedes, J.; Madau, P.; Diemand, J.; Kuhlen, M.; Zemp, M.

    2009-09-10

    The coalescence of a massive black hole (MBH) binary leads to the gravitational-wave recoil of the system and its ejection from the galaxy core. We have carried out N-body simulations of the motion of a M{sub BH} = 3.7 x 10{sup 6} M{sub sun} MBH remnant in the 'Via Lactea I' simulation, a Milky Way-sized dark matter halo. The black hole receives a recoil velocity of V{sub kick} = 80, 120, 200, 300, and 400 km s{sup -1} at redshift 1.5, and its orbit is followed for over 1 Gyr within a 'live' host halo, subject only to gravity and dynamical friction against the dark matter background. We show that, owing to asphericities in the dark matter potential, the orbit of the MBH is highly nonradial, resulting in a significantly increased decay timescale compared to a spherical halo. The simulations are used to construct a semi-analytic model of the motion of the MBH in a time-varying triaxial Navarro-Frenk-White dark matter halo plus a spherical stellar bulge, where the dynamical friction force is calculated directly from the velocity dispersion tensor. Such a model should offer a realistic picture of the dynamics of kicked MBHs in situations where gas drag, friction by disk stars, and the flattening of the central cusp by the returning black hole are all negligible effects. We find that MBHs ejected with initial recoil velocities V{sub kick} {approx}> 500 km s{sup -1} do not return to the host center within a Hubble time. In a Milky Way-sized galaxy, a recoiling hole carrying a gaseous disk of initial mass {approx}M{sub BH} may shine as a quasar for a substantial fraction of its 'wandering' phase. The long decay timescales of kicked MBHs predicted by this study may thus be favorable to the detection of off-nuclear quasar activity.

  9. Recoil velocity at second post-Newtonian order for spinning black hole binaries

    NASA Astrophysics Data System (ADS)

    Racine, Étienne; Buonanno, Alessandra; Kidder, Larry

    2009-08-01

    We compute the flux of linear momentum carried by gravitational waves emitted from spinning binary black holes at second post-Newtonian (2PN) order for generic orbits. In particular we provide explicit expressions of three new types of terms, namely, next-to-leading order spin-orbit terms at 1.5 post-Newtonian (1.5PN) order, spin-orbit tail terms at 2PN order, and spin-spin terms at 2PN order. Restricting ourselves to quasicircular orbits, we integrate the linear-momentum flux over time to obtain the recoil velocity as function of orbital frequency. We find that in the so-called superkick configuration the higher-order spin corrections can increase the recoil velocity up to a factor ˜3 with respect to the leading-order PN prediction. Whereas the recoil velocity computed in PN theory within the adiabatic approximation can accurately describe the early inspiral phase, we find that its fast increase during the late inspiral and plunge, and the arbitrariness in determining until when it should be trusted, makes the PN predictions for the total recoil not very accurate and robust. Nevertheless, the linear-momentum flux at higher PN orders can be employed to build more reliable resummed expressions aimed at capturing the nonperturbative effects until merger. Furthermore, we provide expressions valid for generic orbits, and accurate at 2PN order, for the energy and angular momentum carried by gravitational waves emitted from spinning binary black holes. Specializing to quasicircular orbits we compute the spin-spin terms at 2PN order in the expression for the evolution of the orbital frequency and found agreement with Mikóczi, Vasúth, and Gergely. We also verified that in the limit of extreme mass ratio our expressions for the energy and angular momentum fluxes match the ones of Tagoshi, Shibata, Tanaka, and Sasaki obtained in the context of black hole perturbation theory.

  10. Chemical separation and mass spectrometry of Cr, Fe, Ni, Zn, and Cu in terrestrial and extraterrestrial materials using thermal ionization mass spectrometry.

    PubMed

    Yamakawa, Akane; Yamashita, Katsuyuki; Makishima, Akio; Nakamura, Eizo

    2009-12-01

    A sequential chemical separation technique for Cr, Fe, Ni, Zn, and Cu in terrestrial and extraterrestrial silicate rocks was developed for precise and accurate determination of elemental concentration by the isotope dilution method (ID). The technique uses a combination of cation-anion exchange chromatography and Eichrom nickel specific resin. The method was tested using a variety of matrixes including bulk meteorite (Allende), terrestrial peridotite (JP-1), and basalt (JB-1b). Concentrations of each element was determined by thermal ionization mass spectrometry (TIMS) using W filaments and a Si-B-Al type activator for Cr, Fe, Ni, and Zn and a Re filament and silicic acid-H3PO4 activator for Cu. The method can be used to precisely determine the concentrations of these elements in very small silicate samples, including meteorites, geochemical reference samples, and mineral standards for microprobe analysis. Furthermore, the Cr mass spectrometry procedure developed in this study can be extended to determine the isotopic ratios of 53Cr/52Cr and 54Cr/52Cr with precision of approximately 0.05epsilon and approximately 0.10epsilon (1epsilon = 0.01%), respectively, enabling cosmochemical applications such as high precision Mn-Cr chronology and investigation of nucleosynthetic isotopic anomalies in meteorites. PMID:19886654

  11. Recoil Polarization and Beam-Recoil Double Polarization Measurement of {eta} Electroproduction on the Proton in the Region of the S{sub 11}(1535) Resonance

    SciTech Connect

    Merkel, H.; Achenbach, P.; Ayerbe Gayoso, C.; Bernauer, J. C.; Boehm, R.; Distler, M. O.; Doria, L.; Friedrich, J.; Mueller, U.; Nungesser, L.; Pochodzalla, J.; Sanchez Majos, S.; Schlimme, B. S.; Tiator, L.; Walcher, Th.; Weinriefer, M.; Bosnar, D.; Makek, M.; Cheymol, B.; Fonvieille, H.

    2007-09-28

    The beam-recoil double polarization P{sub x{sup '}}{sup h} and P{sub z{sup '}}{sup h} and the recoil polarization P{sub y{sup '}} were measured for the first time for the p(e-vector,e{sup '}p-vector){eta} reaction at a four-momentum transfer of Q{sup 2}=0.1 GeV{sup 2}/c{sup 2} and a center of mass production angle of {theta}=120 deg. at the Mainz Microtron MAMI-C. With a center of mass energy range of 1500 MeV

  12. Non-separative headspace solid phase microextraction-mass spectrometry profile as a marker to monitor coffee roasting degree.

    PubMed

    Liberto, Erica; Ruosi, Manuela R; Cordero, Chiara; Rubiolo, Patrizia; Bicchi, Carlo; Sgorbini, Barbara

    2013-02-27

    This study describes a non-separative headspace solid phase microextraction-mass spectrometry (HS-SPME-MS) approach, in view of its application to online monitoring of a roasting process. The system can quickly provide representative and diagnostic fingerprints of the volatile fraction of samples and, in combination with appropriate chemometric pattern recognition and regression techniques, can successfully be applied to characterize, discriminate, and/or correlate patterns with the roasting process. Eighty coffee samples of different varieties, geographical origins, and blends were analyzed. The experimental HS-SPME-MS results show that the TIC fingerprint can be used to discriminate the degree of roasting; diagnostic ion abundance(s) or ratios were closely correlated with the roasting process; both could successfully be used as markers or analytical decision makers, to monitor roasting processes online, and to define quality and safety of roasted coffee. PMID:23088249

  13. Geologic and seismic investigations, relocation of Route 3, grade separation at Route 62, southeast ramp in Bedford, Mass.

    USGS Publications Warehouse

    May, James E.

    1954-01-01

    The relocation of Route 3 in Bedford, Mass. requires extensive cuts for a grade separation at Route 62. This report contains only the results of the geologic and seismic studies that were made for the purpose of obtaining information that would aid in the construction of the inner and outer loops of the southeast ramp. The studies represent part of a cooperative program of the Massachusetts Department of Public Works and the United States Geological Survey. The work was performed in July 1953. The site is located in the Wilmington and Lexington 7-1/2-minute quadrangle maps of the United States Geological Survey. Mr. M. E. Chandler and Mr. W. L. Carney, Massachusetts Department of Public works' Engineers, performed all pertinent survey work required for this project, and prepared the essential plans and profiles. Mr. Chandler also operated the seismic equipment and assisted in the preparation of the seismic velocity data.

  14. Determination of rare earth impurities in high purity samarium oxide using inductively coupled plasma mass spectrometry after extraction chromatographic separation

    NASA Astrophysics Data System (ADS)

    Zhang, Xinquan; Liu, Jinglei; Yi, Yong; Liu, Yonglin; Li, Xiang; Su, Yaqin; Lin, Ping

    2007-01-01

    A method for the determination of trace of 14 rare earth elements (REEs) as impurities in high purity samarium oxide (Sm2O3) using inductively coupled plasma mass spectrometry (ICP-MS) was described. Analytes, such as La, Ce, Pr, Nd, Eu, Gd, Tb, Lu and Y were measured without Sm matrix separation because of no interference problems occurring that could affect the analysis of these elements. On the other hand, analytes, such as Dy, Ho, Er, Tm and Yb were carried out after Sm matrix being eliminated completely by means of 2-ethylhexyl hydrogen-ethylhexy phosphonate (EHEHP) extraction chromatographic separation. The inherent problem associated with matrix-induced suppression was effectively compensated with spiking In as internal standard element and the mass spectra isobaric interferences of atomic and molecular ions arose from Sm matrix had been overcome after the removal of Sm matrix. The limits of quantitations (LOQ) for 14 REEs impurities were from 0.01 to 0.07 [mu]g g-1 together with the recoveries of spiking sample of 14 REEs were found to be in the range of 85-110% and the proposed method precision was less than 5%. A synthetic standard Sm2O3 sample with well-known 14 REEs concentrations was prepared and analysed in order to prove the accuracy and precision of the proposed method together with another high purity Sm2O3 was also measured using ICP-MS. The methodology had been found to be suitable for the determination of trace of 14 REEs in 99.999-99.9999% high purity Sm2O3.

  15. Warm target recoil ion momentum spectroscopy for fragmentation of molecular hydrogen by ultrashort laser pulses.

    PubMed

    Liu, Jia; Wu, Jian; Czasch, Achim; Zeng, Heping

    2009-07-20

    We demonstrate warm target recoil ion momentum spectroscopy for the fragmentation dynamics of the warm hydrogen molecules at room temperature. The thermal movement effect of the warm molecule is removed by using a correction algorithm in the momentum space. Based on the reconstructed three-dimensional momentum vectors as well as the kinetic energy release spectra, different vibrational states of the H(2)(+) ground state are clearly visible and the internuclear separation for charge resonance enhanced ionization of the second electron is identified. The results show adequate accordance with the former experiments using other techniques. PMID:19654636

  16. Separation and characterization of phenolic compounds from dry-blanched peanut skins by liquid chromatography-electrospray ionization mass spectrometry.

    PubMed

    Ma, Yuanyuan; Kosińska-Cagnazzo, Agnieszka; Kerr, William L; Amarowicz, Ryszard; Swanson, Ruthann B; Pegg, Ronald B

    2014-08-22

    A large variety of phenolic compounds, including phenolic acids (hydroxybenzoic acids, hydroxycinnamic acids, and their esters), stilbenes (trans-resveratrol and trans-piceatannol), flavan-3-ols (e.g., (-)-epicatechin, (+)-catechin, and their polymers {the proanthocyanidins, PACs}), other flavonoids (e.g., isoflavones, flavanols, and flavones, etc.) and biflavonoids (e.g., morelloflavone), were identified in dry-blanched peanut skins (PS) by this study. High-performance liquid chromatography (HPLC) coupled with electrospray ionization mass spectrometry (ESI-MS(n)) was applied to separate and identify the phenolic constituents. Reversed-phase HPLC was employed to separate free phenolic compounds as well as PAC monomers, dimers, and trimers. PACs with a degree of polymerization (DP) of >4 were chromatographed via hydrophilic interaction liquid chromatography (HILIC). Tentative identification of the separated phenolics was based solely on molecular ions and MS(n) fragmentation patterns acquired by ESI-MS in the negative-ion mode. The connection sequence of PAC oligomers (DP <5) could be deduced mainly through characteristic quinone methide (QM) cleavage ions. When the DP reached 6, only a proportion of the flavan-3-ols could be ascertained in the PACs because of the extremely complicated fragmentation patterns involved. The identification of free phenolic acids, stilbenes, and flavonoids was achieved by authentic commercial standards and also by published literature data. Quantification was performed based on peak areas of the UV (free phenolic compounds) or fluorescence (PACs) signals from the HPLC chromatograms and calibration curves of commercial standards. Overall, PS contain significantly more PACs compared to free phenolic compounds. PMID:25016324

  17. Comprehensive gas chromatography coupled to mass spectrometry for the separation of pesticides in a very complex matrix.

    PubMed

    Mondello, Luigi; Casilli, Alessandro; Tranchida, Peter Quinto; Lo Presti, Maria; Dugo, Paola; Dugo, Giovanni

    2007-11-01

    The present research is focused on the development of a comprehensive two-dimensional gas chromatography-rapid scanning quadrupole mass spectrometric (GC x GC-qMS) methodology for the analysis of trace-amount pesticides contained in a complex real-world sample. Reliable peak assignment was carried out by using a recently developed, dedicated pesticide MS library (for comprehensive GC analysis), characterized by a twin-filter search procedure, the first based on a minimum degree of spectral similarity and the second on the interactive use of linear retention indices (LRI). The library was constructed by subjecting mixtures of commonly used pesticides to GC x GC-qMS analysis and then deriving their pure mass spectra and LRI values. In order to verify the effectiveness of the approach, a pesticide-contaminated red grapefruit extract was analysed. The certainty of peak assignment was attained by exploiting both the enhanced separation power of dual-oven GC x GC and the highly effective search procedure. PMID:17589835

  18. Impact of the equivalent center of mass separating from the sliding surface on the isolation performance of friction pendulum bearings

    NASA Astrophysics Data System (ADS)

    Xia, Junyong; Ning, Xiangliang; Tan, Ping; Hao, Hongxiao; Chen, Guoping

    2015-12-01

    A new equivalent center of mass model of FPBs (friction pendulum bearings) is introduced, and based on this model, coefficient j of the equivalent center of mass separating from the sliding surface is defined. It is thought in theory that j has a significant impact on the isolation parameter of FPBs, since the equivalent post-yielding stiffness and friction coefficients are not simply determined by sliding radius and sliding friction pairs. The results of numerical simulation analysis using ABAQUS conducted on two groups of FPBs support this viewpoint. For FPBs with the same sliding radius and sliding friction pairs, the FPB modules of structural analysis software such as ETABS could only distinguish the equivalent transformation using j one by one. The seismic response data obtained in a base isolation calculation example of FPBs are very different, which reveals that j's impact on the isolation effectiveness of FPBs cannot be ignored. The introduction of j will help improve the classical structural theory of FPBs and the weak points of structural analysis software based on this theory, which is important in achieving more accurate analyses in structural design.

  19. Solvent Separating Secondary Metabolites Directly from Biosynthetic Tissue for Surface-Assisted Laser Desorption Ionisation Mass Spectrometry

    PubMed Central

    Rudd, David; Benkendorff, Kirsten; Voelcker, Nicolas H.

    2015-01-01

    Marine bioactive metabolites are often heterogeneously expressed in tissues both spatially and over time. Therefore, traditional solvent extraction methods benefit from an understanding of the in situ sites of biosynthesis and storage to deal with heterogeneity and maximize yield. Recently, surface-assisted mass spectrometry (MS) methods namely nanostructure-assisted laser desorption ionisation (NALDI) and desorption ionisation on porous silicon (DIOS) surfaces have been developed to enable the direct detection of low molecular weight metabolites. Since direct tissue NALDI-MS or DIOS-MS produce complex spectra due to the wide variety of other metabolites and fragments present in the low mass range, we report here the use of “on surface” solvent separation directly from mollusc tissue onto nanostructured surfaces for MS analysis, as a mechanism for simplifying data annotation and detecting possible artefacts from compound delocalization during the preparative steps. Water, ethanol, chloroform and hexane selectively extracted a range of choline esters, brominated indoles and lipids from Dicathais orbita hypobranchial tissue imprints. These compounds could be quantified on the nanostructured surfaces by comparison to standard curves generated from the pure compounds. Surface-assisted MS could have broad utility for detecting a broad range of secondary metabolites in complex marine tissue samples. PMID:25786067

  20. Median recoil direction as a WIMP directional detection signal

    NASA Astrophysics Data System (ADS)

    Green, Anne M.; Morgan, Ben

    2010-03-01

    Direct detection experiments have reached the sensitivity to detect dark matter weakly interacting massive particles (WIMPs). Demonstrating that a putative signal is due to WIMPs, and not backgrounds, is a major challenge, however. The direction dependence of the WIMP scattering rate provides a potential WIMP “smoking gun.” If the WIMP distribution is predominantly smooth, the Galactic recoil distribution is peaked in the direction opposite to the direction of Solar motion. Previous studies have found that, for an ideal detector, of order 10 WIMP events would be sufficient to reject isotropy, and rule out an isotropic background. We examine how the median recoil direction could be used to confirm the WIMP origin of an anisotropic recoil signal. Specifically, we determine the number of events required to confirm the direction of solar motion as the median inverse recoil direction at 95% confidence. We find that for zero background 31 events are required, a factor of ˜2 more than are required to simply reject isotropy. We also investigate the effect of a nonzero isotropic background. As the background rate is increased the number of events required increases, initially fairly gradually and then more rapidly, once the signal becomes subdominant. We also discuss the effect of features in the speed distribution at large speeds, as found in recent high resolution simulations, on the median recoil direction.

  1. Median recoil direction as a WIMP directional detection signal

    SciTech Connect

    Green, Anne M.; Morgan, Ben

    2010-03-15

    Direct detection experiments have reached the sensitivity to detect dark matter weakly interacting massive particles (WIMPs). Demonstrating that a putative signal is due to WIMPs, and not backgrounds, is a major challenge, however. The direction dependence of the WIMP scattering rate provides a potential WIMP 'smoking gun'. If the WIMP distribution is predominantly smooth, the Galactic recoil distribution is peaked in the direction opposite to the direction of Solar motion. Previous studies have found that, for an ideal detector, of order 10 WIMP events would be sufficient to reject isotropy, and rule out an isotropic background. We examine how the median recoil direction could be used to confirm the WIMP origin of an anisotropic recoil signal. Specifically, we determine the number of events required to confirm the direction of solar motion as the median inverse recoil direction at 95% confidence. We find that for zero background 31 events are required, a factor of {approx}2 more than are required to simply reject isotropy. We also investigate the effect of a nonzero isotropic background. As the background rate is increased the number of events required increases, initially fairly gradually and then more rapidly, once the signal becomes subdominant. We also discuss the effect of features in the speed distribution at large speeds, as found in recent high resolution simulations, on the median recoil direction.

  2. Calculation of recoil implantation profiles using known range statistics

    NASA Technical Reports Server (NTRS)

    Fung, C. D.; Avila, R. E.

    1985-01-01

    A method has been developed to calculate the depth distribution of recoil atoms that result from ion implantation onto a substrate covered with a thin surface layer. The calculation includes first order recoils considering projected range straggles, and lateral straggles of recoils but neglecting lateral straggles of projectiles. Projectile range distributions at intermediate energies in the surface layer are deduced from look-up tables of known range statistics. A great saving of computing time and human effort is thus attained in comparison with existing procedures. The method is used to calculate recoil profiles of oxygen from implantation of arsenic through SiO2 and of nitrogen from implantation of phosphorus through Si3N4 films on silicon. The calculated recoil profiles are in good agreement with results obtained by other investigators using the Boltzmann transport equation and they also compare very well with available experimental results in the literature. The deviation between calculated and experimental results is discussed in relation to lateral straggles. From this discussion, a range of surface layer thickness for which the method applies is recommended.

  3. Stimulated Rayleigh resonances and recoil-induced effects

    SciTech Connect

    Courtois, J.Y.; Grynberg, G.

    1996-12-31

    The organization of this paper is as follows. We present in Section II the basic ideas about stimulated Rayleigh scattering by considering more particularly the situation where it arises from a relaxation process going on in the material system, and we describe a few experimental observations made in atomic and molecular physics. We then consider the case of nonstationary two-level atoms, and we derive the shape and characteristics of the recoil-induced resonances (Section III). In particular, we show that these resonances can be interpreted either as originating from a stimulated Rayleigh effect or as a stimulated Raman phenomena between atomic energy-momentum states having different momenta. Finally, to make a clear distinction between the physical phenomena that pertain directly to recoil-induced processes (i.e., that actually permit the measurement of the photon recoil) and those for which the introduction of the recoil constitutes a mere physical convenience, we review in Section IV some indisputable manifestations of the photon recoil in atomic and molecular physics. 92 refs., 22 figs.

  4. AUTOMATICALLY DETECTING AND TRACKING CORONAL MASS EJECTIONS. I. SEPARATION OF DYNAMIC AND QUIESCENT COMPONENTS IN CORONAGRAPH IMAGES

    SciTech Connect

    Morgan, Huw; Byrne, Jason P.; Habbal, Shadia Rifai

    2012-06-20

    Automated techniques for detecting and tracking coronal mass ejections (CMEs) in coronagraph data are of ever increasing importance for space weather monitoring and forecasting. They serve to remove the biases and tedium of human interpretation, and provide the robust analysis necessary for statistical studies across large numbers of observations. An important requirement in their operation is that they satisfactorily distinguish the CME structure from the background quiescent coronal structure (streamers, coronal holes). Many studies resort to some form of time differencing to achieve this, despite the errors inherent in such an approach-notably spatiotemporal crosstalk. This article describes a new deconvolution technique that separates coronagraph images into quiescent and dynamic components. A set of synthetic observations made from a sophisticated model corona and CME demonstrates the validity and effectiveness of the technique in isolating the CME signal. Applied to observations by the LASCO C2 and C3 coronagraphs, the structure of a faint CME is revealed in detail despite the presence of background streamers that are several times brighter than the CME. The technique is also demonstrated to work on SECCHI/COR2 data, and new possibilities for estimating the three-dimensional structure of CMEs using the multiple viewing angles are discussed. Although quiescent coronal structures and CMEs are intrinsically linked, and although their interaction is an unavoidable source of error in any separation process, we show in a companion paper that the deconvolution approach outlined here is a robust and accurate method for rigorous CME analysis. Such an approach is a prerequisite to the higher-level detection and classification of CME structure and kinematics.

  5. Hyphenation of supercritical fluid chromatography and two-dimensional gas chromatography-mass spectrometry for group type separations.

    PubMed

    Potgieter, H; van der Westhuizen, R; Rohwer, E; Malan, D

    2013-06-14

    The Fischer-Tropsch (FT) process produces a variety of compounds over a wide carbon number range and the synthetic crude oil produced by this process is rich in highly valuable olefins and oxygenates, which crude oil only contains at trace levels. The characterization of these products is very challenging even when using comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC×GC-TOF-MS). The separation between cyclic paraffins and olefins is especially difficult since they elute in similar positions on the GC×GC chromatogram and since they have identical molecular masses with indistinguishable fragmentation patterns. Previously, a high performance liquid chromatography (HPLC) fractionation procedure was used prior to GC×GC-TOF-MS analysis to distinguish between alkenes and alkanes, both cyclic and non-cyclic, however, there was co-elution of the solvents used in the HPLC fractionation procedure, and the volatile components in the gasoline sample and the dilution introduced by the off-line fractionation procedure made it very difficult to investigate components present at very low concentrations. The hyphenation of supercritical fluid chromatography (SFC) to GC×GC is less complicated and the removal of the supercritical CO2 can be easily achieved without any loss of the volatile sample components, eliminating the introduction of co-eluting solvents as well as the dilution effect. This paper describes the on-line hyphenation of SFC to a GC×GC system in order to comprehensively characterize the chemical groups (saturates, unsaturates, oxygenates and aromatics) in an FT sample. PMID:23647609

  6. The effects of upstream mass injection by vortex generator jets on shock-induced turbulent boundary layer separation

    NASA Astrophysics Data System (ADS)

    Bueno, Pablo Cesar

    An experimental study was conducted to investigate the effects of upstream mass injection, by means of vortex generator jets (VGJs), on the shock wave/turbulent boundary layer interaction (SWTBLI) generated by cylinder in a Mach 2 flow. The objectives of the study were: (i) to characterize the changes to the global structure of the flowfield introduced by the VGJs, and (ii) to study how the injection affected the dynamics of the separation shock foot. The injection was provided by three high-speed valves, placed across the span of the test section, which generated underexpanded jets. Two jet orientations were studied: normal to the wall, and pitched at 60° and skewed at 90° with respect to the freestream. In addition, the effects of both continuous and pulsed injection were investigated. Velocity measurements of the upstream boundary layer, VGJs, and -shock system were made using a wide-field particle image velocimetry (PIV) system, and an array of fast-response pressure transducers was used to monitor the wall pressure under the intermittent region of the interaction. The velocity measurements of the baseline case captured nearly all the relevant flow structures including the -shock and primary and secondary vortices. However, neither mean supersonic reversed flow nor the supersonic jet that presumably exists downstream of the triple point were observed. When injection was applied, the scale of the separated flow changed considerably. For normal injection, the primary vortex was nearly suppressed, while for pitched/skewed injection, the secondary vortex increased in size. Mean streamwise and transverse velocity profiles upstream of the separation shock showed that, for both jet orientations, the VGJs caused the flow in the boundary layer to accelerate. However, for normal injection, the acceleration did not extend down to the wall. Phase-averaged velocity measurements of the opening phase of the valves indicated that there is a phase lag between the jets and the

  7. Nuclear Recoil Calibration of DarkSide-50

    NASA Astrophysics Data System (ADS)

    Edkins, Erin; DarkSide Collaboration

    2016-03-01

    DarkSide-50 dark matter experiment is a liquid argon time projection chamber (TPC) surrounded by a liquid scintillator active neutron veto, designed for the direct detection of Weakly Interacting Massive Particles (WIMPs). The success of such an experiment is dependent upon a detailed understanding of both the expected signal and backgrounds, achieved using radioactive calibration sources of known energies. Nuclear recoils provide a measurement of both the expected signal and the most dangerous background, as nuclear recoils from neutrons cannot be distinguished from a dark matter signal on an event-by-event basis in the TPC. In this talk, I will present the DS-50 calibration system, and analysis of the results of the calibration of DarkSide-50 to nuclear recoils using radioactive neutron sources. See also the DS-50 presentations by X. Xiang and G. Koh.

  8. Rupture and recoil of bent-core liquid crystal filaments.

    PubMed

    Salili, S M; Ostapenko, T; Kress, O; Bailey, C; Weissflog, W; Harth, K; Eremin, A; Stannarius, R; Jákli, A

    2016-05-25

    The recoil process of free-standing liquid crystal filaments is investigated experimentally and theoretically. We focus on two aspects, the contraction speed of the filament and a spontaneously formed undulation instability. At the moment of rupture, the filaments buckle similarly to the classical Euler buckling of elastic rods. The tip velocity decays with decreasing filament length. The wavelength of buckling affinely decreases with the retracting filament tip. The energy gain related to the decrease of the total length and surface area of the filaments is mainly dissipated by layer rearrangements during thickening of the fibre. A flow back into the meniscus is relevant only in the final stage of the recoil process. We introduce a model for the quantitative description of the filament retraction speed. The dynamics of this recoil behaviour may find relevance as a model for biology-related filaments. PMID:27140824

  9. Accounting for Recoil Effects in Geochronometers: A New Model Approach

    NASA Astrophysics Data System (ADS)

    Lee, V. E.; Huber, C.

    2012-12-01

    A number of geologically important chronometers are affected by, or owe their utility to, the "recoil effect". This effect describes the physical displacement of a nuclide due to energetic nuclear processes such as radioactive alpha decay (as in the case of various parent-daughter pairs in the uranium-series decay chains, and Sm-Nd), as well as neutron irradiation (in the case of the methodology for the 40Ar/39Ar dating method). The broad range of affected geochronometers means that the recoil effect can impact a wide range of dating method applications in the geosciences, including but not limited to: Earth surface processes, paleoclimate, volcanic processes, and cosmochemistry and planetary evolution. In particular, the recoil effect can have a notable impact on the use of fine grains (silt- and clay-sized particles) for geochronometric dating purposes. This is because recoil-induced loss of a nuclide from the surfaces of a grain can create an isotopically-depleted outer rind, and for small grains, this depleted rind can be volumetrically significant. When this recoil loss is measurable and occurs in a known time-dependent fashion, it can usefully serve as the basis for chronometers (such as the U-series comminution age method); in other cases recoil loss from fine particles creates an unwanted deviation from expected isotope values (such as for the Ar-Ar method). To improve both the accuracy and precision of ages inferred from geochronometric systems that involve the recoil of a key nuclide from small domains, it is necessary to quantify the magnitude of the recoil loss of that particular nuclide. It is also necessary to quantitatively describe the effect of geological processes that can alter the outer surface of grains, and hence the isotopically-depleted rind. Here we present a new mathematical and numerical model that includes two main features that enable enhanced accuracy and precision of ages determined from geochronometers. Since the surface area of the

  10. Recoil release of fission products from nuclear fuel

    NASA Astrophysics Data System (ADS)

    Wise, C.

    1985-10-01

    An analytical approximation is developed for calculating recoil release from nuclear fuel into gas filled interspaces. This expression is evaluated for a number of interspace geometries and shown to be generally accurate to within about 10% by comparison with numerical calculations. The results are applied to situations of physical interest and it is demonstrated that recoil can be important when modelling fission product release from low temperature CAGR pin failures. Furthermore, recoil can contribute significantly in experiments on low temperature fission product release, particularly where oxidation enhancement of this release is measured by exposing the fuel to CO 2. The calculations presented here are one way of allowing for this, other methods are suggested.

  11. Fission product release from nuclear fuel by recoil and knockout

    NASA Astrophysics Data System (ADS)

    Lewis, B. J.

    1987-03-01

    An analytical model has been developed to describe the fission product release from nuclear fuel arising from the surface-fission release mechanisms of recoil and knockout. Release expressions are evaluated and compared to the short-lived activity measurements from in-reactor experiments with intact operating fuel. Recoil is shown to be an important process for releasing fission products from free UO 2 surfaces into the fuel-to-sheath gap. The model is also applied to tramp uranium in a power reactor primary heat transport circuit where it is demonstrated that recoil is the dominant release mechanism for small particles of fuel which are deposited on in-core surfaces. A methodology is established whereby release from surface contamination can be distinguished from that of fuel pin failure.

  12. A high-performance multiple-reflection time-of-flight mass spectrometer and isobar separator for the research with exotic nuclei

    NASA Astrophysics Data System (ADS)

    Dickel, T.; Plaß, W. R.; Becker, A.; Czok, U.; Geissel, H.; Haettner, E.; Jesch, C.; Kinsel, W.; Petrick, M.; Scheidenberger, C.; Simon, A.; Yavor, M. I.

    2015-03-01

    A novel multiple-reflection time-of-flight mass spectrometer (MR-TOF-MS) and isobar separator for the research with exotic nuclides at low-energy rare isotope beam facilities has been developed, commissioned and characterized. It can be used (i) as broadband mass spectrometer with medium resolution, (ii) as highly accurate mass spectrometer for direct mass measurements and (iii) as high-resolution mass separator. The device features a worldwide unique combination of performance characteristics: a mass resolving power of 600,000 (FWHM), a mass measurement accuracy of ~10-7, large ion capacities in excess of 106 ions per second, a transmission efficiency of up to 70%, single-ion sensitivity, and cycle frequencies of up to 400 Hz have been achieved. The spatial separation of close-lying isobars with an intensity ratio of 200:1 and a binding energy difference as small as 4 MeV has been demonstrated. The MR-TOF-MS is ideally suited for experiments with rare and very short-lived nuclei at present and future in-flight, ISOL or IGISOL facilities, such as the FRS Ion-Catcher and SHIP/SHIPTRAP at GSI, TITAN at TRIUMF, IGISOL at the University of Jyväskylä and the Low-Energy Branch of the Super-FRS at FAIR.

  13. Ionic recoil energies in the Coulomb explosion of metal clusters

    NASA Astrophysics Data System (ADS)

    Teuber, S.; Döppner, T.; Fennel, T.; Tiggesbäumker, J.; Meiwes-Broer, K. H.

    The photoionization of metal clusters in intense femtosecond laser fields has been studied. In contrast to an experiment on atoms, the interaction in this case leads to a very efficient and high charging of the particle where tens of electrons per atom are ejected from the cluster. The recoil energy distribution of the atomic fragment ions was measured which in the case of lead clusters exceeds 180 keV. Enhanced charging efficiency which we observed earlier for specific pulse conditions is not reflected in the recoil energy spectra. Both the average and the maximum energies decrease with increasing laser pulse width. This is in good agreement with molecular dynamics calculations.

  14. Status and Prospects of the HERMES Recoil Detector

    SciTech Connect

    Mussgiller, Andreas

    2009-08-04

    Hard exclusive processes provide access to generalized parton distributions (GPDs), which extend our description of the nucleon structure beyond the standard parton distributions. The Deeply Virtual Compton Scattering (DVCS) process provides the theoretically cleanest access to the GPDs. For the final two years of data taking, a recoil detector was installed at HERMES for the purpose of improving the ability to measure hard-exclusive processes. In addition the recoil detector allows one to measure the individual background contributions which can be used to refine previously published results on DVCS. The progress of the ongoing data analysis is presented.

  15. Modified ion exchange separation for tungsten isotopic measurements from kimberlite samples using multi-collector inductively coupled plasma mass spectrometry.

    PubMed

    Sahoo, Yu Vin; Nakai, Shun'ichi; Ali, Arshad

    2006-03-01

    Tungsten isotope composition of a sample of deep-seated rock can record the influence of core-mantle interaction of the parent magma. Samples of kimberlite, which is known as a carrier of diamond, from the deep mantle might exhibit effects of core-mantle interaction. Although tungsten isotope anomaly was reported for kimberlites from South Africa, a subsequent investigation did not verify the anomaly. The magnesium-rich and calcium-rich chemical composition of kimberlite might engender difficulty during chemical separation of tungsten for isotope analyses. This paper presents a simple, one-step anion exchange technique for precise and accurate determination of tungsten isotopes in kimberlites using multi-collector inductively coupled plasma mass spectrometry (MC-ICP-MS). Large quantities of Ca and Mg in kimberlite samples were precipitated and removed with aqueous H(2)SO(4). Highly pure fractions of tungsten for isotopic measurements were obtained following an anion exchange chromatographic procedure involving mixed acids. That procedure enabled efficient removal of high field strength elements (HFSE), such as Hf, Zr and Ti, which are small ions that carry strong charges and develop intense electrostatic fields. The tungsten yields were 85%-95%. Advantages of this system include less time and less use of reagents. Precise and accurate isotopic measurements are possible using fractions of tungsten that are obtained using this method. The accuracy and precision of these measurements were confirmed using various silicate standard rock samples, JB-2, JB-3 and AGV-1. PMID:16496054

  16. Conception of PIPERADE: A high-capacity Penning-trap mass separator for high isobaric contamination at DESIR

    NASA Astrophysics Data System (ADS)

    Minaya Ramirez, E.; Alfaurt, P.; Aouadi, M.; Ascher, P.; Blank, B.; Blaum, K.; Cam, J.-F.; Chauveau, P.; Daudin, L.; Delahaye, P.; Delalee, F.; Dupré, P.; El Abbeir, S.; Gerbaux, M.; Grévy, S.; Guérin, H.; Lunney, D.; Metz, F.; Naimi, S.; Perrot, L.; de Roubin, A.; Serani, L.; Thomas, B.; Thomas, J.-C.

    2016-06-01

    The DESIR (decay, excitation and storage of radioactive ions) facility at GANIL-SPIRAL2 will receive a large variety of exotic nuclei at low energy (up to 60 keV) with high intensities. However, the production methods of radioactive beams are non selective, limiting the purity of the beams of interest. Moreover, the high precision needed for nuclear structure and astrophysics studies using beta decay spectroscopy, laser spectroscopy and trap-based experiments at DESIR requires highly pure samples of exotic nuclei. The aim of the double-Pennig-trap mass separator PIPERADE is to deliver large and very pure samples of exotic nuclei to the different experiments in DESIR. New excitation schemes and a large inner diameter of the first trap will mitigate space charge effects to attempt trapping of up to 105 ions per pulse. The purification cycle will be performed in a few milliseconds so that short-lived nuclei can be purified. To extract the nuclides of interest from the large amount of isobaric contaminants, a resolving power of 105 is mandatory. Afterwards the ions of interest will be accumulated in the second trap until they constitute a sufficiently pure sample for the measurements. The status of the project is presented.

  17. Enantioselective separation and pharmacokinetic dissipation of cyflumetofen in field soil by ultra-performance convergence chromatography with tandem mass spectrometry.

    PubMed

    Liu, Na; Dong, Fengshou; Xu, Jun; Liu, Xingang; Chen, Zenglong; Pan, Xinglu; Chen, Xixi; Zheng, Yongquan

    2016-04-01

    Little data on the enantioselective separation of cyflumetofen exists, despite the fact that such data are essential to the assessment of the fate and potential toxic effects of cyflumetofen enantiomers. To address this issue, a simple and sensitive method for the enantioselective determination of cyflumetofen enantiomers in soil has been established using ultra performance convergence chromatography tandem triple quadrupole mass spectrometry. The effects of the chiral stationary phases, mobile phase, auto backpressure regulator pressure, column temperature, flow rate of the mobile phase, and compensation pump solvent were evaluated. The proposed method was applied to the study of the pharmacokinetic dissipation of cyflumetofen stereoisomers in soil under greenhouse conditions. The estimated half-life of cyflumetofen isomers ranged from 12.2 to 13.6 days, and statistically significant enantioselective degradation was observed. This study not only demonstrates that there is an efficient and sensitive method for cyflumetofen enantioseparation, but also provides the first experimental evidence of the pharmacokinetic dissipation of cyflumetofen stereoisomers in the environment. PMID:26834082

  18. Automated screening of reversed-phase stationary phases for small-molecule separations using liquid chromatography with mass spectrometry.

    PubMed

    Appulage, Dananjaya K; Wang, Evelyn H; Carroll, Frances; Schug, Kevin A

    2016-05-01

    There are various reversed-phase stationary phases that offer significant differences in selectivity and retention. To investigate different reversed-phase stationary phases (aqueous stable C18 , biphenyl, pentafluorophenyl propyl, and polar-embedded alkyl) in an automated fashion, commercial software and associated hardware for mobile phase and column selection were used in conjunction with liquid chromatography and a triple quadrupole mass spectrometer detector. A model analyte mixture was prepared using a combination of standards from varying classes of analytes (including drugs, drugs of abuse, amino acids, nicotine, and nicotine-like compounds). Chromatographic results revealed diverse variations in selectivity and peak shape. Differences in the elution order of analytes on the polar-embedded alkyl phase for several analytes showed distinct selectivity differences compared to the aqueous C18 phase. The electron-rich pentafluorophenyl propyl phase showed unique selectivity toward protonated amines. The biphenyl phase provided further changes in selectivity relative to C18 with a methanolic phase, but it behaved very similarly to a C18 when an acetonitrile-based mobile phase was evaluated. This study shows the value of rapid column screening as an alternative to excessive mobile phase variation to obtain suitable chromatographic settings for analyte separation. PMID:26959840

  19. Phage amplification and immunomagnetic separation combined with targeted mass spectrometry for sensitive detection of viable bacteria in complex food matrices.

    PubMed

    Martelet, Armelle; L'Hostis, Guillaume; Nevers, Marie-Claire; Volland, Hervé; Junot, Christophe; Becher, François; Muller, Bruno H

    2015-06-01

    We have developed and describe here for the first time a highly sensitive method for the fast and unambiguous detection of viable Escherichia coli in food matrices. The new approach is based on using label-free phages (T4), obligate parasites of bacteria, which are attractive for pathogen detection because of their inherent natural specificity and ease of use. A specific immunomagnetic separation was used to capture the progeny phages produced. Subsequently, T4 phage markers were detected by liquid chromatography coupled to targeted mass spectrometry. Combining the specificity of these three methodologies is of great interest in developing an alternative to conventional time-consuming culture-based technologies for the detection of viable bacteria for industrial applications. First, optimization experiments with phage T4 spiked in complex matrices (without a phage amplification event) were performed and demonstrated specific, sensitive, and reproducible phage capture and detection in complex matrices including Luria-Bertani broth, orange juice, and skimmed milk. The method developed was then applied to the detection of E. coli spiked in foodstuffs (with a phage amplification event). After having evaluated the impact of infection duration on assay sensitivity, we showed that our assay specifically detects viable E. coli in milk at an initial count of ≥1 colony-forming unit (cfu)/mL after an 8-h infection. This excellent detection limit makes our new approach an alternative to PCR-based assays for rapid bacterial detection. PMID:25932746

  20. Mass

    SciTech Connect

    Chris Quigg

    2007-12-05

    In the classical physics we inherited from Isaac Newton, mass does not arise, it simply is. The mass of a classical object is the sum of the masses of its parts. Albert Einstein showed that the mass of a body is a measure of its energy content, inviting us to consider the origins of mass. The protons we accelerate at Fermilab are prime examples of Einsteinian matter: nearly all of their mass arises from stored energy. Missing mass led to the discovery of the noble gases, and a new form of missing mass leads us to the notion of dark matter. Starting with a brief guided tour of the meanings of mass, the colloquium will explore the multiple origins of mass. We will see how far we have come toward understanding mass, and survey the issues that guide our research today.

  1. The Final Merger of Massive Black Holes: Recoils, Gravitational Waves, and Electromagnetic Signatures

    NASA Technical Reports Server (NTRS)

    Centrella, Joan M.

    2010-01-01

    The final merger of two massive black holes produces a powerful burst of gravitational radiation, emitting more energy than all the stars in the observable universe combined. The resulting gravitational waveforms will be easily detectable by the space-based LISA out to redshifts z greater than 10, revealing the masses and spins of the black holes to high precision. If the merging black holes have unequal masses, or asymmetric spins, the final black hole that forms can recoil with a velocity exceeding 1000 km/s. And, when the black holes merge in the presence of gas and magnetic fields, various types of electromagnetic signals may also be produced. For more than 30 years, scientists have tried to compute black hole mergers using the methods of numerical relativity. The resulting computer codes have been plagued by instabilities, causing them to crash well before the black holes in the binary could complete even a single orbit. Within the past few years, however, this situation has changed dramatically, with a series of remarkable breakthroughs. This talk will focus on new results that are revealing the dynamics and waveforms of binary black hole mergers, recoil velocities, and the possibility of accompanying electromagnetic outbursts.

  2. Elastic recoil can either amplify or attenuate muscle-tendon power, depending on inertial vs. fluid dynamic loading.

    PubMed

    Richards, Christopher T; Sawicki, Gregory S

    2012-11-21

    Frog jumps exceed muscle power limits. To achieve this, a muscle may store elastic energy in tendon before it is released rapidly, producing 'power amplification' as tendon recoil assists the muscle to accelerate the load. Do the musculoskeletal modifications conferring power amplification help or hinder frog swimming? We used a Hill-type mathematical model of a muscle-tendon (MT) with contractile element (CE) and series elastic element (SEE) properties of frogs. We varied limb masses from 0.3 to 30 g, foot-fin areas from 0.005 to 50 cm(2) and effective mechanical advantage (EMA=in-lever/out-lever) from 0.025 to 0.1. 'Optimal' conditions produced power amplification of ~19% greater than the CE limit. Yet, other conditions caused ~80% reduction of MT power (power attenuation) due to SEE recoil absorbing power from (rather than adding to) the CE. The tendency for elastic recoil to cause power amplification vs. attenuation was load dependent: low fluid drag loads, high limb mass and EMA=0.1 caused power amplification whereas high drag, low mass and low EMA (=0.025) caused attenuation. Power amplification emerged when: (1) CE shortening velocity is 1/3V(max), (2) elastic energy storage is neither too high nor too low, and (3). peak inertial-drag force ratio ≥ ~1.5. Excessive elastic energy storage delayed the timing of recoil, causing power attenuation. Thus our model predicts that for fluid loads, the benefit from a compliant tendon is modest, and when the system is 'poorly tuned' (i.e., inappropriate EMA), MT power attenuation can be severe. PMID:22898554

  3. Direct Measurement of Photon Recoil from a Levitated Nanoparticle

    NASA Astrophysics Data System (ADS)

    Jain, Vijay; Gieseler, Jan; Moritz, Clemens; Dellago, Christoph; Quidant, Romain; Novotny, Lukas

    2016-06-01

    The momentum transfer between a photon and an object defines a fundamental limit for the precision with which the object can be measured. If the object oscillates at a frequency Ω0 , this measurement backaction adds quanta ℏΩ0 to the oscillator's energy at a rate Γrecoil, a process called photon recoil heating, and sets bounds to coherence times in cavity optomechanical systems. Here, we use an optically levitated nanoparticle in ultrahigh vacuum to directly measure Γrecoil. By means of a phase-sensitive feedback scheme, we cool the harmonic motion of the nanoparticle from ambient to microkelvin temperatures and measure its reheating rate under the influence of the radiation field. The recoil heating rate is measured for different particle sizes and for different excitation powers, without the need for cavity optics or cryogenic environments. The measurements are in quantitative agreement with theoretical predictions and provide valuable guidance for the realization of quantum ground-state cooling protocols and the measurement of ultrasmall forces.

  4. Direct Measurement of Photon Recoil from a Levitated Nanoparticle.

    PubMed

    Jain, Vijay; Gieseler, Jan; Moritz, Clemens; Dellago, Christoph; Quidant, Romain; Novotny, Lukas

    2016-06-17

    The momentum transfer between a photon and an object defines a fundamental limit for the precision with which the object can be measured. If the object oscillates at a frequency Ω_{0}, this measurement backaction adds quanta ℏΩ_{0} to the oscillator's energy at a rate Γ_{recoil}, a process called photon recoil heating, and sets bounds to coherence times in cavity optomechanical systems. Here, we use an optically levitated nanoparticle in ultrahigh vacuum to directly measure Γ_{recoil}. By means of a phase-sensitive feedback scheme, we cool the harmonic motion of the nanoparticle from ambient to microkelvin temperatures and measure its reheating rate under the influence of the radiation field. The recoil heating rate is measured for different particle sizes and for different excitation powers, without the need for cavity optics or cryogenic environments. The measurements are in quantitative agreement with theoretical predictions and provide valuable guidance for the realization of quantum ground-state cooling protocols and the measurement of ultrasmall forces. PMID:27367388

  5. Isotopic disequilibrium of uranium: alpha-recoil damage and preferential solution effects

    SciTech Connect

    Fleischer, R.L.

    1980-02-29

    Preferential loss of uranium-234 relative to uranium-238 from rocks into solutions has long been attributed to recoiling alpha-emitting nuclei. Direct evidence has been obtained for two mechanisms, first, recoil ejection from grains, and now release by natural etching of alpha-recoil tracks. The observations have implications for radon emanation and for the storage of alpha-emitting radioactive waste.

  6. 7Be recoil implantation for ultra-thin-layer-activation of medical grade polyethylene: Effect on wear resistance

    NASA Astrophysics Data System (ADS)

    Hoffmann, M.; Abbas, K.; Sauvage, T.; Blondiaux, G.; Vincent, L.; Stroosnijder, M. F.

    2001-10-01

    Wear of ultra-high-molecular-weight-polyethylene (UHMWPE) is usually measured by gravimetric methods making laboratory wear tests a time consuming exercise. Methods for the determination of polyethylene wear with a higher sensitivity would reduce test times and costs. One of these alternative methods is ultra-thin-layer-activation (UTLA), which relies on recoil implantation of heavy radioactive nuclei, such as 7Be, by using light mass particle beams. However, the possibility of damages within the polyethylene surface, which would have consequences on its wear behavior, cannot be excluded. In this work the effect of an implantation of 7Be on wear of a medical grade UHMWPE was studied using a block-on-cylinder screening wear tester. The results show that the implantation of UHMWPE with 7Be recoils under the implantation conditions chosen does not alter the tribological behavior of medical grade UHMWPE.

  7. Spallation recoil II: Xenon evidence for young SiC grains

    NASA Astrophysics Data System (ADS)

    Ott, U.; Altmaier, M.; Herpers, U.; Kuhnhenn, J.; Merchel, S.; Michel, R.; Mohapatra, R. K.

    2005-11-01

    We have determined the recoil range of spallation xenon produced by irradiation of Ba glass targets with ˜1190 and ˜268 MeV protons, using a catcher technique, where spallation products are measured in target and catcher foils. The inferred range for 126Xe produced in silicon carbide is ˜0.19 μm, which implies retention of ˜70% for 126Xe produced in "typical" presolar silicon carbide grains of 1 μm size. Recoil loss of spallation xenon poses a significantly smaller problem than loss of the spallation neon from SiC grains. Ranges differ for the various Xe isotopes and scale approximately linearly as function of the mass difference between the target element, Ba, and the product. As a consequence, SiC grains of various sizes will have differences in spallation Xe composition. In an additional experiment at ˜66 MeV, where the recoil ranges of 22Na and 127Xe produced on Ba glass were determined using γ-spectrometry, we found no evidence for recoil ranges being systematically different at this lower energy. We have used the new data to put constraints on the possible presolar age of the SiC grains analyzed for Xe by Lewis et al. (1994). Uncertainties in the composition of the approximately normal Xe component in SiC (Xe-N) constitute the most serious problem in determining an age, surpassing remaining uncertainties in Xe retention and production rate. A possible interpretation is that spallation contributions are negligible and that trapped 124Xe/126Xe is ˜5% lower in Xe-N than in Q-Xe. But also for other reasonable assumptions for the 124Xe/126Xe ratio in Xe-N (e.g., as in Q-Xe), inferred exposure ages are considerably shorter than theoretically expected lifetimes for interstellar grains. A short presolar age is in line with observations by others (appearance, grain size distribution) that indicate little processing in the interstellar medium (ISM) of surviving (crystalline) SiC. This may be due to amorphization of SiC in the ISM on a much shorter time scale

  8. A recoil resilient lumen support, design, fabrication and mechanical evaluation

    NASA Astrophysics Data System (ADS)

    Mehdizadeh, Arash; Ali, Mohamed Sultan Mohamed; Takahata, Kenichi; Al-Sarawi, Said; Abbott, Derek

    2013-06-01

    Stents are artificial implants that provide scaffolding to a cavity inside the body. This paper presents a new luminal device for reducing the mechanical failure of stents due to recoil, which is one of the most important issues in stenting. This device, which we call a recoil-resilient ring (RRR), is utilized standalone or potentially integrated with existing stents to address the problem of recoil. The proposed structure aims to minimize the need for high-pressure overexpansion that can induce intra-luminal trauma and excess growth of vascular tissue causing later restenosis. The RRR is an overlapped open ring with asymmetrical sawtooth structures that are intermeshed. These teeth can slide on top of each other, while the ring is radially expanded, but interlock step-by-step so as to keep the final expanded state against compressional forces that normally cause recoil. The RRRs thus deliver balloon expandability and, when integrated with a stent, bring both radial rigidity and longitudinal flexibility to the stent. The design of the RRR is investigated through finite element analysis (FEA), and then the devices are fabricated using micro-electro-discharge machining of 200-µm-thick Nitinol sheet. The standalone RRR is balloon expandable in vitro by 5-7 Atm in pressure, which is well within the recommended in vivo pressure ranges for stenting procedures. FEA compression tests indicate 13× less reduction of the cross-sectional area of the RRR compared with a typical stainless steel stent. These results also show perfect elastic recovery of the RRR after removal of the pressure compared to the remaining plastic deformations of the stainless steel stent. On the other hand, experimental loading tests show that the fabricated RRRs have 2.8× radial stiffness compared to a two-column section of a commercial stent while exhibiting comparable elastic recovery. Furthermore, testing of in vitro expansion in a mock artery tube shows around 2.9% recoil, approximately 5-11

  9. Relativistic nuclear recoil, electron correlation and QED effects in highly charged Ar ions

    NASA Astrophysics Data System (ADS)

    Harman, Z.; Soria Orts, R.; Lapierre, A.; Crespo Lopez-Urrutia, J. R.; Artemyev, A. N.; Tupitsyn, I. I.; Jentschura, U. D.; Keitel, C. H.; Tawara, H.; Ullrich, J.; Shabaev, V. M.; Volotka, A. V.

    2007-06-01

    We have performed extensive theoretical studies on the 1s^22s^22p^2P3/2 -- ^2P1/2 M1 transition in Ar^13+ ions. Accurate radiative lifetimes are sensitive to QED corrections like the electron anomalous magnetic moment and to relativistic electron correlation effects. The lifetime of the P3/2 metastable state was determined to be 9.573(4)(5) ms (stat)(syst) [1] using the Heidelberg electron beam ion trap. Theoretical predictions cluster around a value that is significantly shorter than this high-precision experimental result. This discrepancy is presently unexplained. The wavelengths of the above transition in Ar^13+ and the 1s^22s2p ^3P1 -- ^3P2 M1 transition in Ar^14+ were compared for the isotopes ^36Ar and ^40Ar [2]. The observed mass shift has confirmed the relativistic theory of nuclear recoil effects in many-body systems. Our calculations, based on the fully relativistic recoil operator, are in excellent agreement with the measured results. [1] A. Lapierre, U.D. Jentschura, J.R. Crespo L'opez-Urrutia et al., Phys. Rev. Lett. 95, 183001 (2005); [2] R. Soria Orts, Z. Harman, J.R. Crespo L'opez-Urrutia et al., Phys. Rev. Lett. 97, 103002 (2006)

  10. Oxygen recoil implant from SiO{sub 2} layers into single-crystalline silicon

    SciTech Connect

    Wang, G.; Chen, Y.; Li, D.; Oak, S.; Srivastav, G.; Banerjee, S.; Tasch, A.; Merrill, P.; Bleiler, R.

    2001-06-01

    It is important to understand the distribution of recoil-implanted atoms and the impact on device performance when ion implantation is performed at a high dose through surface materials into single crystalline silicon. For example, in ultralarge scale integration impurity ions are often implanted through a thin layer of screen oxide and some of the oxygen atoms are inevitably recoil implanted into single-crystalline silicon. Theoretical and experimental studies have been performed to investigate this phenomenon. We have modified the Monte Carlo ion implant simulator, UT-Marlowe (B. Obradovic, G. Wang, Y. Chen, D. Li, C. Snell, and A. F. Tasch, UT-MARLOWE Manual, 1999), which is based on the binary collision approximation, to follow the full cascade and to dynamically modify the stoichiometry of the Si layer as oxygen atoms are knocked into it. CPU reduction techniques are used to relieve the demand on computational power when such a full cascade simulation is involved. Secondary ion mass spectrometry (SIMS) profiles of oxygen have been carefully obtained for high dose As and BF{sub 2} implants at different energies through oxide layers of various thicknesses, and the simulated oxygen profiles are found to agree very well with the SIMS data. {copyright} 2001 American Institute of Physics.

  11. Differential cross sections and recoil polarizations for the reaction γp→K+Σ0

    NASA Astrophysics Data System (ADS)

    Dey, B.; Meyer, C. A.; Bellis, M.; McCracken, M. E.; Williams, M.; Adhikari, K. P.; Aghasyan, M.; Anghinolfi, M.; Ball, J.; Battaglieri, M.; Batourine, V.; Bedlinskiy, I.; Berman, B. L.; Biselli, A. S.; Branford, D.; Briscoe, W. J.; Brooks, W. K.; Burkert, V. D.; Carman, D. S.; Crede, V.; D'Angelo, A.; Daniel, A.; de Vita, R.; de Sanctis, E.; Deur, A.; Dhamija, S.; Dickson, R.; Djalali, C.; Doughty, D.; Dugger, M.; Dupre, R.; El Alaoui, A.; El Fassi, L.; Eugenio, P.; Fegan, S.; Fradi, A.; Gabrielyan, M. Y.; Gilfoyle, G. P.; Giovanetti, K. L.; Girod, F. X.; Gohn, W.; Gothe, R. W.; Graham, L.; Griffioen, K. A.; Guler, N.; Guo, L.; Hafidi, K.; Hakobyan, H.; Hanretty, C.; Hassall, N.; Hicks, K.; Holtrop, M.; Ilieva, Y.; Ireland, D. G.; Jawalkar, S. S.; Jo, H. S.; Joo, K.; Keller, D.; Khandaker, M.; Khetarpal, P.; Kim, A.; Kim, W.; Klein, A.; Klein, F. J.; Konczykowski, P.; Kubarovsky, V.; Kuleshov, S. V.; Kuznetsov, V.; Livingston, K.; MacGregor, I. J. D.; Martinez, D.; McAndrew, J.; McKinnon, B.; Mikhailov, K.; Mirazita, M.; Mokeev, V.; Moreno, B.; Moriya, K.; Morrison, B.; Moutarde, H.; Munevar, E.; Nadel-Turonski, P.; Nasseripour, R.; Nepali, C. S.; Ni, A.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Niroula, M. R.; Osipenko, M.; Ostrovidov, A. I.; Paremuzyan, R.; Park, K.; Park, S.; Pasyuk, E.; Pereira, S. Anefalos; Pogorelko, O.; Pozdniakov, S.; Price, J. W.; Procureur, S.; Protopopescu, D.; Raue, B. A.; Ricco, G.; Ripani, M.; Ritchie, B. G.; Rosner, G.; Rossi, P.; Salamanca, J.; Salgado, C.; Schott, D.; Schumacher, R. A.; Seder, E.; Seraydaryan, H.; Sharabian, Y. G.; Smith, E. S.; Smith, G. D.; Sober, D. I.; Sokhan, D.; Stepanyan, S. S.; Strakovsky, I. I.; Strauch, S.; Tang, W.; Taylor, C. E.; Tedeschi, D. J.; Tkachenko, S.; Ungaro, M.; Watts, D. P.; Vernarsky, B.; Vineyard, M. F.; Voutier, E.; Weinstein, L. B.; Wood, M. H.; Yegneswaran, A.; Zhang, J.; Zhao, B.; Zhao, Z. W.

    2010-08-01

    High-statistics measurements of differential cross sections and recoil polarizations for the reaction γp→K+Σ0 have been obtained using the CLAS detector at Jefferson Lab. We cover center-of-mass energies (s) from 1.69 to 2.84 GeV, with an extensive coverage in the K+ production angle. Independent measurements were made using the K+pπ-(γ) and K+p(π-,γ) final-state topologies, and were found to exhibit good agreement. Our differential cross sections show good agreement with earlier CLAS, SAPHIR, and LEPS results, while offering better statistical precision and a 300-MeV increase in s coverage. Above s≈2.5 GeV, t- and u-channel Regge scaling behavior can be seen at forward and backward angles, respectively. Our recoil polarization (PΣ) measurements represent a substantial increase in kinematic coverage and enhanced precision over previous world data. At forward angles, we find that PΣ is of the same order of magnitude but opposite sign as PΛ, in agreement with the static SU(6) quark model prediction of PΣ≈-PΛ. This expectation is violated in some mid- and backward-angle kinematic regimes, where PΣ and PΛ are of similar magnitudes but also have the same signs. In conjunction with several other meson photoproduction results recently published by CLAS, the present data will help constrain the partial-wave analyses being performed to search for missing baryon resonances.

  12. CDMS detector fabrication improvements and low energy nuclear recoil measurements in germanium

    NASA Astrophysics Data System (ADS)

    Jastram, Andrew Karl

    As the CDMS (Cryogenic Dark Matter Search) experiment is scaled up to tackle new dark matter parameter spaces (lower masses and cross-sections), detector production efficiency and repeatability becomes ever more important. A dedicated facility has been commissioned for SuperCDMS detector fabrication at Texas A&M University (TAMU). The fabrication process has been carefully tuned using this facility and its equipment. Production of successfully tested detectors has been demonstrated. Significant improvements in detector performance have been made using new fabrication methods, equipment, and tuning of process parameters. This work has demonstrated the capability for production of next generation CDMS SNOLAB detectors. Additionally, as the dark matter parameter space is probed further, careful calibrations of detector response to nuclear recoil interactions must be performed in order to extract useful information (in relation to dark matter particle characterizations) from experimental results. A neutron beam of tunable energy is used in conjunction with a commercial radiation detector to characterize ionization energy losses in germanium during nuclear recoil events. Data indicates agreement with values predicted by the Lindhard equation, providing a best-fit k-value of 0.146.

  13. Method for quantitative determination and separation of trace amounts of chemical elements in the presence of large quantities of other elements having the same atomic mass

    DOEpatents

    Miller, C.M.; Nogar, N.S.

    1982-09-02

    Photoionization via autoionizing atomic levels combined with conventional mass spectroscopy provides a technique for quantitative analysis of trace quantities of chemical elements in the presence of much larger amounts of other elements with substantially the same atomic mass. Ytterbium samples smaller than 10 ng have been detected using an ArF* excimer laser which provides the atomic ions for a time-of-flight mass spectrometer. Elemental selectivity of greater than 5:1 with respect to lutetium impurity has been obtained. Autoionization via a single photon process permits greater photon utilization efficiency because of its greater absorption cross section than bound-free transitions, while maintaining sufficient spectroscopic structure to allow significant photoionization selectivity between different atomic species. Separation of atomic species from others of substantially the same atomic mass is also described.

  14. A Study of Intrinsic Statistical Variation for Nuclear Recoils in Germanium Detector for Dark Matter Searches

    NASA Astrophysics Data System (ADS)

    Wei, Wenzhao; Wang, Lu; Mei, Dongming; Cubed Collaboration

    2015-10-01

    The intrinsic statistical variation in nuclear recoils is a critical part that cannot be ignored when calculating energy resolution of germanium detector in detecting WIMPs. Have a good theoretical understanding about the intrinsic statistical variation in nuclear recoils and develop a model for calculating this variation based on experimental data is of great importance in determining the width of nuclear recoil band, which is used to identify nuclear recoils events. Hence, we designed an experiment to study the intrinsic statistical variation in nuclear recoils with various gamma sources and AmBe neutron source. In addition, we developed a theoretical model to calculate the intrinsic statistical variation in nuclear recoils based on data from AmBe neutron source. In this work, we will present our data and theoretical calculation for nuclear recoils. This work is supported by NSF in part by the NSF PHY-0758120, DOE grant DE-FG02-10ER46709, and the State of South Dakota.

  15. Characterization of the CRESST detectors by neutron induced nuclear recoils

    NASA Astrophysics Data System (ADS)

    Coppi, C.; Ciemniak, C.; von Feilitzsch, F.; Gütlein, A.; Hagn, H.; Isaila, C.; Jochum, J.; Kimmerle, M.; Lanfranchi, J.-C.; Pfister, S.; Potzel, W.; Rau, W.; Roth, S.; Rottler, K.; Sailer, C.; Scholl, S.; Usherov, I.; Westphal, W.

    CRESST is an experiment for the direct detection of dark matter particles via nuclear recoils. The CRESST detectors, based on CaWO4 scintillating crystals, are able to discriminate γ and β background by simultaneously measuring the light and phonon signals produced by particle interactions. The discrimination of the background is possible because of the different light output (Quenching Factor, QF) for nuclear and electron recoils. In this article a measurement is shown, aimed at the determination of the QFs of the different nuclei (O, Ca, W) of the detector crystal at 40-60 mK using an 11 MeV neutron beam produced at the Maier-Leibnitz-Laboratorium in Garching (MLL).

  16. Separating the Chaff from the Oats: Evidence for a Conceptual Distinction between Count Noun and Mass Noun Aggregates

    ERIC Educational Resources Information Center

    Middleton, Erica L.; Wisniewski, Edward J.; Trindel, Kelly A.; Imai, Mutsumi

    2004-01-01

    The English language makes a grammatical distinction between count nouns and mass nouns. For example, count nouns but not mass nouns can be pluralized and can appear with the indefinite article. Some scholars dismiss the distinction as an arbitrary convention of language whereas others suggest that it is conceptually based. The present studies…

  17. Recoiling supermassive black holes: a search in the nearby universe

    SciTech Connect

    Lena, D.; Robinson, A.; Axon, D. J.; Merritt, D.; Marconi, A.; Capetti, A.; Batcheldor, D.

    2014-11-10

    The coalescence of a binary black hole can be accompanied by a large gravitational recoil due to anisotropic emission of gravitational waves. A recoiling supermassive black hole (SBH) can subsequently undergo long-lived oscillations in the potential well of its host galaxy, suggesting that offset SBHs may be common in the cores of massive ellipticals. We have analyzed Hubble Space Telescope archival images of 14 nearby core ellipticals, finding evidence for small (≲ 10 pc) displacements between the active galactic nucleus (AGN; the location of the SBH) and the center of the galaxy (the mean photocenter) in 10 of them. Excluding objects that may be affected by large-scale isophotal asymmetries, we consider six galaxies to have detected displacements, including M87, where a displacement was previously reported by Batcheldor et al. In individual objects, these displacements can be attributed to residual gravitational recoil oscillations following a major or minor merger within the last few gigayears. For plausible merger rates, however, there is a high probability of larger displacements than those observed, if SBH coalescence took place in these galaxies. Remarkably, the AGN-photocenter displacements are approximately aligned with the radio source axis in four of the six galaxies with displacements, including three of the four having relatively powerful kiloparsec-scale jets. This suggests intrinsic asymmetries in radio jet power as a possible displacement mechanism, although approximate alignments are also expected for gravitational recoil. Orbital motion in SBH binaries and interactions with massive perturbers can produce the observed displacement amplitudes but do not offer a ready explanation for the alignments.

  18. Recoil Polarization for Neutral Pion Electroproduction near the Delta Resonance

    SciTech Connect

    Kelly, James J

    2003-10-01

    We have measured angular distributions for recoil polarization in the p(e,e'p)p0 reaction at Q2»1(GeV/c)2 with 1.16 |lte| W |lte|1.36 GeV across the D resonance. The data are compared with representative models and a truncated Legendre analysis is compared with a more general multipole analysis.

  19. Absolute cross section for recoil detection of deuterium

    NASA Astrophysics Data System (ADS)

    Besenbacher, F.; Stensgaard, I.; Vase, P.

    1986-04-01

    The D( 4He, D) 4He cross section used for recoil detection of deuterium (D) has been calibrated on an absolute scale against the cross section of the D( 3He, α)p nuclear reaction which is often used for D profiling. For 4He energies ranging from 0.8 to ~1.8 MeV. the D( 4He, D) 4He cross section varies only slightly with incident energy and recoil angle θ (for 0° ⩽ 8 ⩽ 35°) and has a value of ~ 500 mb/sr which is significantly higher than the ~ 65 mb/sr c.m.s. cross section of the D( 3He, α)p nuclear reaction. For 4He energies ranging from ~ 1.9 to ~ 2.3 MeV, the D( 4He,D) 4He cross section exhibits a fairly narrow resonance peak (fwhm ~ 70 keV), with a maximum value (for θ = 0°) of ~ 8.5 b/sr, corresponding to a 4He energy of ~ 2130 keV. The large values of the cross section in connection with the described energy dependence makes the use of forward-recoil detection of D attractive for many purposes, e.g., D Jepth profiling (with an extreme gain in sensitivity), absolute concentration or coverage measurements, and lattice-location experiments by transmission channeling.

  20. The recoil proton polarization in. pi. p elastic scattering

    SciTech Connect

    Seftor, C.J.

    1988-09-01

    The polarization of the recoil proton for ..pi../sup +/p and ..pi../sup -/p elastic scattering has been measured for various angles at 547 MeV/c and 625 MeV/c by a collaboration involving The George Washington University; the University of California, Los Angeles; and Abilene Christian University. The experiment was performed at the P/sup 3/ East experimental area of the Los Alamos Meson Physics Facility. Beam intensities varied from 0.4 to 1.0 x 10/sup 7/ ..pi../sup -/'s/sec and from 3.0 to 10.0 x 10/sup 7/ ..pi../sup +/'s/sec. The beam spot size at the target was 1 cm in the horizontal direction by 2.5 cm in the vertical direction. A liquid-hydrogen target was used in a flask 5.7 cm in diameter and 10 cm high. The scattered pion and recoil proton were detected in coincidence using the Large Acceptance Spectrometer (LAS) to detect and momentum analyze the pions and the JANUS recoil proton polarimeter to detect and measure the polarization of the protons. Results from this experiment are compared with previous measurements of the polarization, with analyzing power data previously taken by this group, and to partial-wave analysis predictions. 12 refs., 53 figs., 18 tabs.

  1. Solid-state Marx based two-switch voltage modulator for the On-Line Isotope Mass Separator accelerator at the European Organization for Nuclear Research.

    PubMed

    Redondo, L M; Silva, J Fernando; Canacsinh, H; Ferrão, N; Mendes, C; Soares, R; Schipper, J; Fowler, A

    2010-07-01

    A new circuit topology is proposed to replace the actual pulse transformer and thyratron based resonant modulator that supplies the 60 kV target potential for the ion acceleration of the On-Line Isotope Mass Separator accelerator, the stability of which is critical for the mass resolution downstream separator, at the European Organization for Nuclear Research. The improved modulator uses two solid-state switches working together, each one based on the Marx generator concept, operating as series and parallel switches, reducing the stress on the series stacked semiconductors, and also as auxiliary pulse generator in order to fulfill the target requirements. Preliminary results of a 10 kV prototype, using 1200 V insulated gate bipolar transistors and capacitors in the solid-state Marx circuits, ten stages each, with an electrical equivalent circuit of the target, are presented, demonstrating both the improved voltage stability and pulse flexibility potential wanted for this new modulator. PMID:20687749

  2. Solid-state Marx based two-switch voltage modulator for the On-Line Isotope Mass Separator accelerator at the European Organization for Nuclear Research

    NASA Astrophysics Data System (ADS)

    Redondo, L. M.; Silva, J. Fernando; Canacsinh, H.; Ferrão, N.; Mendes, C.; Soares, R.; Schipper, J.; Fowler, A.

    2010-07-01

    A new circuit topology is proposed to replace the actual pulse transformer and thyratron based resonant modulator that supplies the 60 kV target potential for the ion acceleration of the On-Line Isotope Mass Separator accelerator, the stability of which is critical for the mass resolution downstream separator, at the European Organization for Nuclear Research. The improved modulator uses two solid-state switches working together, each one based on the Marx generator concept, operating as series and parallel switches, reducing the stress on the series stacked semiconductors, and also as auxiliary pulse generator in order to fulfill the target requirements. Preliminary results of a 10 kV prototype, using 1200 V insulated gate bipolar transistors and capacitors in the solid-state Marx circuits, ten stages each, with an electrical equivalent circuit of the target, are presented, demonstrating both the improved voltage stability and pulse flexibility potential wanted for this new modulator.

  3. Solid-state Marx based two-switch voltage modulator for the On-Line Isotope Mass Separator accelerator at the European Organization for Nuclear Research

    SciTech Connect

    Redondo, L. M.; Canacsinh, H.; Ferrao, N.; Mendes, C.; Silva, J. Fernando; Soares, R.; Schipper, J.; Fowler, A.

    2010-07-15

    A new circuit topology is proposed to replace the actual pulse transformer and thyratron based resonant modulator that supplies the 60 kV target potential for the ion acceleration of the On-Line Isotope Mass Separator accelerator, the stability of which is critical for the mass resolution downstream separator, at the European Organization for Nuclear Research. The improved modulator uses two solid-state switches working together, each one based on the Marx generator concept, operating as series and parallel switches, reducing the stress on the series stacked semiconductors, and also as auxiliary pulse generator in order to fulfill the target requirements. Preliminary results of a 10 kV prototype, using 1200 V insulated gate bipolar transistors and capacitors in the solid-state Marx circuits, ten stages each, with an electrical equivalent circuit of the target, are presented, demonstrating both the improved voltage stability and pulse flexibility potential wanted for this new modulator.

  4. Desorption electrospray ionization mass spectrometry analysis of lipids after two-dimensional high-performance thin-layer chromatography partial separation

    PubMed Central

    Paglia, Giuseppe; Ifa, Demian R.; Wu, Chunping; Corso, Gaetano; Cooks, R. Graham

    2010-01-01

    Molecular imaging of separate but still incompletely resolved spots on high-performance thin-layer chromatography (HPTLC) plates is used for the direct analysis of porcine brain lipids by desorption electrospray ionization mass spectrometry (DESI-MS). Seven class-specific spots were imaged in the negative ion mode and shown to contain more than fifty lipids. A low lateral resolution of 400 × 400 μm allowed simple, rapid and incomplete separation to be combined with DESI imaging for the identification of many components of these extremely complex mixtures. In this work, tandem mass spectrometry (MS/MS) was also employed to confirm the identity of particular lipids directly on HPTLC plates. PMID:20128616

  5. Lifetime measurement of 2+- state in 74Zn by recoil-distance Doppler-shift method

    NASA Astrophysics Data System (ADS)

    Niikura, M.; Mouginot, B.; Azaiez, F.; Franchoo, S.; Matea, I.; Stefan, I.; Verney, D.; Assie, M.; Bednarczyk, P.; Borcea, C.; Burger, A.; Burgunder, G.; Buta, A.; Cáceres, L.; Cléement, E.; Coquard, L.; de Angelis, G.; de France, G.; de Oliveira Santos, F.; Dewald, A.; Dijon, A.; Dombradi, Z.; Fiori, E.; Fransen, C.; Friessner, G.; Gaudefroy, L.; Georgiev, G.; Grévy, S.; Hackstein, M.; Harakeh, M. N.; Ibrahim, F.; Kamalou, O.; Kmiecik, M.; Lozeva, R.; Maj, A.; Mihai, C.; Möller, O.; Myalski, S.; Negoita, F.; Pantelica, D.; Perrot, L.; Pissulla, Th.; Rotaru, F.; Rother, W.; Scarpaci, J. A.; Stodel, C.; Thomas, J. C.; Ujic, P.

    2013-09-01

    We have performed the first direct lifetime measurement of the 2+- state in 74Zn. The neutron-rich 74Zn beam was produced by in-flight fragmentation of 76Ge at the Grand Accélérateur National d'Ions Lourds and separated with the LISE spectrometer. The lifetime of the 2+- state was measured by the recoil-distance Doppler-shift method with the Cologne plunger device combined with the EXOGAM detectors. The lifetime of the 2+- state in 74Zn was determined to be 27.0(24) ps, which corresponds to a reduced transition probability B(E2; 2+- -> 0+) = 370(33) e2fm4.

  6. Gas-phase separation of drugs and metabolites using modifier-assisted differential ion mobility spectrometry hyphenated to liquid extraction surface analysis and mass spectrometry.

    PubMed

    Porta, Tiffany; Varesio, Emmanuel; Hopfgartner, Gérard

    2013-12-17

    The present work describes an alternative generic approach to LC-MS for the analysis of drugs of abuse as well as their metabolites in post-mortem tissue samples. The platform integrates liquid extraction surface analysis (LESA) for analytes tissue extraction followed by differential ion mobility spectrometry (DMS) mass spectrometry for analytes gas phase separation. Detection is performed on a triple quadrupole linear ion trap using the selected reaction monitoring mode for quantification as well as product ion scan mode for structural confirmatory analyses. The major advantages of the platform are that neither chromatographic separation nor extensive sample preparation are required. In DMS the combination of a high separation voltage (i.e., up to 4 kV) together with organic modifiers (e.g., alcohols, acetonitrile, acetone) added in the drift gas is required to achieve the separation of isomeric metabolites, such as the ones of cocaine and tramadol. DMS also separates morphine from its glucuronide metabolites, which allows for preventing the overestimation of morphine in case of fragmentation of the glucuronides in the atmospheric-to-vacuum interface of the mass spectrometer. Cocaine, opiates, opioids, amphetamines, benzodiazepines and several of their metabolites could be identified in post-mortem human kidney and muscle tissue based on simultaneous screening and confirmatory analysis in data-dependent acquisition mode using an analyte-dependent compensation voltage to selectively transmit ions through the DMS cell to the mass analyzer. Quantitative performance of the LESA-DMS-MS platform was evaluated for cocaine and two of its metabolites spotted onto a tissue section using deuterated internal standard. Analyte's responses were linear from 2 to 1000 pg on tissue corresponding to a limit of detection in the order of nanograms of analyte per gram of tissue. Accuracy and precision based on QC sample was found to be less than 10%. Replicate analyses of cocaine and

  7. Extra-large remnant recoil velocities and spins from near-extremal-Bowen-York-spin black-hole binaries

    NASA Astrophysics Data System (ADS)

    Dain, Sergio; Lousto, Carlos O.; Zlochower, Yosef

    2008-07-01

    We evolve equal-mass, equal-spin black-hole binaries with specific spins of a/mH˜0.925, the highest spins simulated thus far and nearly the largest possible for Bowen-York black holes, in a set of configurations with the spins counteraligned and pointing in the orbital plane, which maximizes the recoil velocities of the merger remnant, as well as a configuration where the two spins point in the same direction as the orbital angular momentum, which maximizes the orbital hangup effect and remnant spin. The coordinate radii of the individual apparent horizons in these cases are very small and the simulations require very high central resolutions ( htilde M/320). We find that these highly spinning holes reach a maximum recoil velocity of ˜3300kms-1 (the largest simulated so far) and, for the hangup configuration, a remnant spin of a/mH˜0.922. These results are consistent with our previous predictions for the maximum recoil velocity of ˜4000kms-1 and remnant spin; the latter reinforcing the prediction that cosmic censorship is not violated by merging highly spinning black-hole binaries. We also numerically solve the initial data for, and evolve, a single maximal-Bowen-York-spin black hole, and confirm that the 3-metric has an O(r-2) singularity at the puncture, rather than the usual O(r-4) singularity seen for nonmaximal spins.

  8. Separation and Identification of Isomeric Glycans by Selected Accumulation-Trapped Ion Mobility Spectrometry-Electron Activated Dissociation Tandem Mass Spectrometry.

    PubMed

    Pu, Yi; Ridgeway, Mark E; Glaskin, Rebecca S; Park, Melvin A; Costello, Catherine E; Lin, Cheng

    2016-04-01

    One of the major challenges in structural characterization of oligosaccharides is the presence of many structural isomers in most naturally occurring glycan mixtures. Although ion mobility spectrometry (IMS) has shown great promise in glycan isomer separation, conventional IMS separation occurs on the millisecond time scale, largely restricting its implementation to fast time-of-flight (TOF) analyzers which often lack the capability to perform electron activated dissociation (ExD) tandem MS analysis and the resolving power needed to resolve isobaric fragments. The recent development of trapped ion mobility spectrometry (TIMS) provides a promising new tool that offers high mobility resolution and compatibility with high-performance Fourier transform ion cyclotron resonance (FTICR) mass spectrometers when operated under the selected accumulation-TIMS (SA-TIMS) mode. Here, we present our initial results on the application of SA-TIMS-ExD-FTICR MS to the separation and identification of glycan linkage isomers. PMID:26959868

  9. Development of cadmium/silver/palladium separation by ion chromatography with quadrupole inductively coupled plasma mass spectrometry detection for off-line cadmium isotopic measurements.

    PubMed

    Gautier, C; Bourgeois, M; Isnard, H; Nonell, A; Stadelmann, G; Goutelard, F

    2011-08-01

    A separation method was investigated to perform off-line cadmium isotopic measurements on a (109)Ag transmutation target. Ion chromatography (IC) with Q ICPMS detection (quadrupole inductively coupled plasma mass spectrometry detection) was chosen to separate cadmium from the isobarically interfering elements, silver and palladium, present in the sample. The optimization of chromatographic conditions was particularly studied. Several anion and cation columns (Dionex AG11(®), CS10(®) and CS12(®)) were compared with different mobile phases (HNO(3), HCl). The separation procedure was achieved with a carboxylate-functionalized cation exchange CS12 column using 0.5 M HNO(3) as eluent. The developed technique yielded satisfactory results in terms of separation factors (greater than 5) and provides an efficient solution to obtain rapidly purified cadmium fractions (decontamination factors higher 100,000 for silver and palladium) which can directly be analyzed by multi collection inductively coupled plasma mass spectrometry (MC ICPMS). By applying the proposed procedure, accurate and precise cadmium isotope ratios were determined for the irradiated (109)Ag transmutation target. PMID:21703628

  10. Effect of bend separation distance on the mass transfer in back-to-back pipe bends arranged in a 180° configuration

    NASA Astrophysics Data System (ADS)

    Chen, X.; Le, T.; Ewing, D.; Ching, C. Y.

    2016-02-01

    The mass transfer to turbulent flow through back-to-back pipe bends arranged in a 180° configuration with different lengths of pipe between the bends was measured using a dissolving gypsum test section in water. The measurements were performed for bends with a radius of curvature of 1.5 times the pipe diameter (D) at a Reynolds numbers of 70,000 and Schmidt number of 1280. The maximum mass transfer in the bends decreased from approximately 1.8 times the mass transfer in the upstream pipe when there was no separation distance between the bends to 1.7 times when there was a 1D or 5D length of pipe between the bends. The location of the maximum mass transfer was on the inner sidewall downstream of the second bend when there was no separation distance between the bends. This location changed to the inner wall at the beginning of the second bend when there was a 1D long pipe between the bends, and to the inner sidewall at the end of the first bend when there was a 5D long pipe between the bends.

  11. Topographical and Chemical Imaging of a Phase Separated Polymer Using a Combined Atomic Force Microscopy/Infrared Spectroscopy/Mass Spectrometry Platform.

    PubMed

    Tai, Tamin; Karácsony, Orsolya; Bocharova, Vera; Van Berkel, Gary J; Kertesz, Vilmos

    2016-03-01

    In this paper, the use of a hybrid atomic force microscopy/infrared spectroscopy/mass spectrometry imaging platform was demonstrated for the acquisition and correlation of nanoscale sample surface topography and chemical images based on infrared spectroscopy and mass spectrometry. The infrared chemical imaging component of the system utilized photothermal expansion of the sample at the tip of the atomic force microscopy probe recorded at infrared wave numbers specific to the different surface constituents. The mass spectrometry-based chemical imaging component of the system utilized nanothermal analysis probes for thermolytic surface sampling followed by atmospheric pressure chemical ionization of the gas phase species produced with subsequent mass analysis. The basic instrumental setup, operation, and image correlation procedures are discussed, and the multimodal imaging capability and utility are demonstrated using a phase separated poly(2-vinylpyridine)/poly(methyl methacrylate) polymer thin film. The topography and both the infrared and mass spectral chemical images showed that the valley regions of the thin film surface were comprised primarily of poly(2-vinylpyridine) and hill or plateau regions were primarily poly(methyl methacrylate). The spatial resolution of the mass spectral chemical images was estimated to be 1.6 μm based on the ability to distinguish surface features in those images that were also observed in the topography and infrared images of the same surface. PMID:26890087

  12. First measurements of the absolute neutron spectrum using the Magnetic Recoil Spectrometer (MRS) at the NIF

    NASA Astrophysics Data System (ADS)

    Frenje, J.; Casey, D.; Li, C.; Seguin, F.; Petrasso, R.; Bionta, R.; Cerjan, C.; Eckart, M.; Haan, S.; Hatchett, S.; Khater, H.; Landen, O.; MacKinnon, A.; Moran, M.; Rygg, J.; Kilkenny, J.; Glebov, V.; Sangster, T.; Meyerhofer, D.; Magoon, J.; Fletcher, K.; Leeper, R.

    2010-11-01

    Proper assembly of capsule mass, as manifested through evolution of fuel areal density (ρR), is fundamentally important for achieving hot-spot ignition planned at the National Ignition Facility (NIF). Experimental information about ρR and ρR asymmetries, Ti and yield is therefore essential for understanding how this assembly occurs. To obtain this information, a neutron spectrometer, called the Magnetic-Recoil Spectrometer (MRS) has been implemented on the NIF. Its primary objective is to measure the absolute neutron spectrum in the range 5 to 30 MeV, from which ρR, Ti and yield can be directly inferred for both low-yield tritium-hydrogen-deuterium (THD) and high-yield DT implosions. In this talk, the results from the first measurements of the absolute neutron spectrum produced in exploding pusher and THD implosions will be presented. This work was supported in part by the U.S. DOE, LLNL and LLE.

  13. Supermassive recoil velocities for binary black-hole mergers with antialigned spins.

    PubMed

    González, José A; Hannam, Mark; Sperhake, Ulrich; Brügmann, Bernd; Husa, Sascha

    2007-06-01

    Recent calculations of the recoil velocity in binary black-hole mergers have found the kick velocity to be of the order of a few hundred km/s in the case of nonspinning binaries and about 500 km/s in the case of spinning configurations, and have lead to predictions of a maximum kick of up to 1300 km/s. We test these predictions and demonstrate that kick velocities of at least 2500 km/s are possible for equal-mass binaries with antialigned spins in the orbital plane. Kicks of that magnitude are likely to have significant repercussions for models of black-hole formation, the population of intergalactic black holes, and the structure of host galaxies. PMID:17677893

  14. ASTROPHYSICS. Exclusion of leptophilic dark matter models using XENON100 electronic recoil data.

    PubMed

    2015-08-21

    Laboratory experiments searching for galactic dark matter particles scattering off nuclei have so far not been able to establish a discovery. We use data from the XENON100 experiment to search for dark matter interacting with electrons. With no evidence for a signal above the low background of our experiment, we exclude a variety of representative dark matter models that would induce electronic recoils. For axial-vector couplings to electrons, we exclude cross sections above 6 × 10(-35) cm(2) for particle masses of m(χ) = 2 GeV/c(2). Independent of the dark matter halo, we exclude leptophilic models as an explanation for the long-standing DAMA/LIBRA signal, such as couplings to electrons through axial-vector interactions at a 4.4σ confidence level, mirror dark matter at 3.6σ, and luminous dark matter at 4.6σ. PMID:26293959

  15. Exclusion of leptophilic dark matter models using XENON100 electronic recoil data

    NASA Astrophysics Data System (ADS)

    Collaboration, The XENON; Aprile, E.; Agostini, F.; Alfonsi, M.; Arazi, L.; Arisaka, K.; Arneodo, F.; Auger, M.; Balan, C.; Barrow, P.; Baudis, L.; Bauermeister, B.; Behrens, A.; Brown, A.; Brown, E.; Bruenner, S.; Bruno, G.; Budnik, R.; Bütikofer, L.; Cardoso, J. M. R.; Cervantes, M.; Coderre, D.; Colijn, A. P.; Contreras, H.; Cussonneau, J. P.; Decowski, M. P.; Di Giovanni, A.; Duchovni, E.; Fattori, S.; Ferella, A. D.; Fieguth, A.; Fulgione, W.; Gao, F.; Garbini, M.; Geis, C.; Goetzke, L. W.; Grignon, C.; Gross, E.; Hampel, W.; Itay, R.; Kaether, F.; Kaminsky, B.; Kessler, G.; Kish, A.; Landsman, H.; Lang, R. F.; Le Calloch, M.; Lellouch, D.; Levinson, L.; Levy, C.; Lindemann, S.; Lindner, M.; Lopes, J. A. M.; Lyashenko, A.; Macmullin, S.; Undagoitia, T. Marrodán; Masbou, J.; Massoli, F. V.; Mayani, D.; Fernandez, A. J. Melgarejo; Meng, Y.; Messina, M.; Miguez, B.; Molinario, A.; Morana, G.; Murra, M.; Naganoma, J.; Ni, K.; Oberlack, U.; Orrigo, S. E. A.; Pakarha, P.; Pantic, E.; Persiani, R.; Piastra, F.; Pienaar, J.; Plante, G.; Priel, N.; Rauch, L.; Reichard, S.; Reuter, C.; Rizzo, A.; Rosendahl, S.; dos Santos, J. M. F.; Sartorelli, G.; Schindler, S.; Schreiner, J.; Schumann, M.; Lavina, L. Scotto; Selvi, M.; Shagin, P.; Simgen, H.; Teymourian, A.; Thers, D.; Tiseni, A.; Trinchero, G.; Tunnell, C.; Vitells, O.; Wall, R.; Wang, H.; Weber, M.; Weinheimer, C.

    2015-08-01

    Laboratory experiments searching for galactic dark matter particles scattering off nuclei have so far not been able to establish a discovery. We use data from the XENON100 experiment to search for dark matter interacting with electrons. With no evidence for a signal above the low background of our experiment, we exclude a variety of representative dark matter models that would induce electronic recoils. For axial-vector couplings to electrons, we exclude cross sections above 6 × 10-35 cm2 for particle masses of mχ = 2 GeV/c2. Independent of the dark matter halo, we exclude leptophilic models as an explanation for the long-standing DAMA/LIBRA signal, such as couplings to electrons through axial-vector interactions at a 4.4σ confidence level, mirror dark matter at 3.6σ, and luminous dark matter at 4.6σ.

  16. Identification and separation of saxitoxins using hydrophilic interaction liquid chromatography coupled to traveling wave ion mobility-mass spectrometry.

    PubMed

    Poyer, Salomé; Loutelier-Bourhis, Corinne; Coadou, Gaël; Mondeguer, Florence; Enche, Julien; Bossée, Anne; Hess, Philipp; Afonso, Carlos

    2015-01-01

    The aim of this work was to develop a reliable and efficient analytical method to characterise and differentiate saxitoxin analogues (STX), including sulphated (gonyautoxins, GTX) and non-sulphated analogues. For this purpose, hydrophilic interaction liquid chromatography (HILIC) was used to separate sulphated analogues. We also resorted to ion mobility spectrometry to differentiate the STX analogues because this technique adds a new dimension of separation based on ion gas phase conformation. Positive and negative ionisation modes were used for gonyautoxins while positive ionisation mode was used for non-sulphated analogues. Subsequently, the coupling of these three complementary techniques, HILIC-IM-MS, permitted the separation and identification of STX analogues; isomer differentiation was achieved in HILIC dimension while non-sulphated analogues were separated in the IM-MS dimension. Additional structural characteristics concerning the conformation of STXs could be obtained using IM-MS measurements. Thus, the collision cross sections (CCS) of STXs are reported for the first time in the positive ionisation mode. These experimental CCSs correlated well with the calculated CCS values using the trajectory method. PMID:25601690

  17. A design study for a compact two stage in-flight separator with a high mass resolution and large acceptance

    SciTech Connect

    Hwang, Ji-Gwang; Kim, Eun-San; Hatanaka, Kichiji

    2015-03-15

    The rare isotope beam separator with a large angular acceptance and energy acceptance is essential for examining the characteristics of unstable nuclei and exotic nuclear reactions. Careful design, however, is required to compensate for the effects of high order aberrations induced by large aperture magnets, which are used to collect rare isotopes obtained from a high energy primary heavy-ion beam hitting a target. In order to minimize the effect of the high order aberration, the optics was based on the mirror symmetry optics, which provides smaller high order aberrations, for the separation of {sup 132}Sn produced by a fission reaction between the primary beam of {sup 238}U and a relatively thick Pb target. The designed optics provides energy acceptance (full), horizontal angular acceptance, and vertical acceptance of approximately 8%, 60 mrad, and 130 mrad, respectively.

  18. A design study for a compact two stage in-flight separator with a high mass resolution and large acceptance.

    PubMed

    Hwang, Ji-Gwang; Kim, Eun-San; Hatanaka, Kichiji

    2015-03-01

    The rare isotope beam separator with a large angular acceptance and energy acceptance is essential for examining the characteristics of unstable nuclei and exotic nuclear reactions. Careful design, however, is required to compensate for the effects of high order aberrations induced by large aperture magnets, which are used to collect rare isotopes obtained from a high energy primary heavy-ion beam hitting a target. In order to minimize the effect of the high order aberration, the optics was based on the mirror symmetry optics, which provides smaller high order aberrations, for the separation of (132)Sn produced by a fission reaction between the primary beam of (238)U and a relatively thick Pb target. The designed optics provides energy acceptance (full), horizontal angular acceptance, and vertical acceptance of approximately 8%, 60 mrad, and 130 mrad, respectively. PMID:25832210

  19. Modeling of mass transfer of Phospholipids in separation process with supercritical CO2 fluid by RBF artificial neural networks

    Technology Transfer Automated Retrieval System (TEKTRAN)

    An artificial Radial Basis Function (RBF) neural network model was developed for the prediction of mass transfer of the phospholipids from canola meal in supercritical CO2 fluid. The RBF kind of artificial neural networks (ANN) with orthogonal least squares (OLS) learning algorithm were used for mod...

  20. Photo-ionisation mass spectrometry as detection method for gas chromatography. Optical selectivity and multidimensional comprehensive separations.

    PubMed

    Zimmermann, Ralf; Welthagen, Werner; Gröger, Thomas

    2008-03-14

    Mass spectrometry (MS) with soft ionisation techniques (i.e. ionisation without fragmentation of the analyte molecules) for gaseous samples exhibits interesting analytical properties for direct analysis applications (i.e. direct inlet mass spectrometric on-line monitoring) as well as mass spectrometric detection method for gas chromatography (GC-MS). Commonly either chemical ionisation (CI) or field ionisation (FI) is applied as soft ionisation technology for GC-MS. An interesting alternative to the CI and FI technologies methods are photo-ionisation (PI) methods. PI overcomes some of the limitations of CI and FI and furthermore add some unique analytical properties. The resonance enhanced multi-photon ionisation (REMPI) method uses intense UV-laser pulses (wavelength range approximately 350-193 nm) for highly selective, sensitive and soft ionisation of predominately aromatic compounds. The single photon ionisation (SPI) method utilises VUV light (from lamps or laser sources, wavelengths range approximately 150-110 nm) can be used for a universal soft ionisation of organic molecules. In this article the historical development as well as the current status and concepts of gas chromatography hyphenated to photo-ionisation mass spectrometry are reviewed. PMID:17915237

  1. UTILITY OF THREE TYPES OF MASS SPECTROMETERS FOR DETERMINING ELEMENTAL COMPOSITIONS OF IONS FORMED FROM CHROMATOGRAPHICALLY SEPARATED COMPOUNDS

    EPA Science Inventory

    Sponsor Referee: Douglas F. Barofsky, Oregon State University Concentration factors of 1000 and more reveal dozens of compounds in extracts of water supplies. Library mass spectra for most of these compounds are not available, and alternative means of identification are needed. D...

  2. THERMOSPRAY MASS SPECTROMETRY IONIZATION PROCESSES FUNDAMENTAL MECHANISMS FOR SPECIATION, SEPARATION AND CHARACTERIZATION OF ORGANIC COMPLEXANTS IN DOE WASTES

    EPA Science Inventory

    In order to understand the equilibria of organic complexants and their products in multi-component mixtures this task will develop and interpret positive and negative ion thermospray mass spectra of complexants and complexant products using liquid chromatography combined with the...

  3. Determination of plutonium isotopes (238Pu, 239Pu, 240Pu, 241Pu) in environmental samples using radiochemical separation combined with radiometric and mass spectrometric measurements.

    PubMed

    Xu, Yihong; Qiao, Jixin; Hou, Xiaolin; Pan, Shaoming; Roos, Per

    2014-02-01

    This paper reports an analytical method for the determination of plutonium isotopes ((238)Pu, (239)Pu, (240)Pu, (241)Pu) in environmental samples using anion exchange chromatography in combination with extraction chromatography for chemical separation of Pu. Both radiometric methods (liquid scintillation counting and alpha spectrometry) and inductively coupled plasma mass spectrometry (ICP-MS) were applied for the measurement of plutonium isotopes. The decontamination factors for uranium were significantly improved up to 7.5 × 10(5) for 20 g soil compared to the level reported in the literature, this is critical for the measurement of plutonium isotopes using mass spectrometric technique. Although the chemical yield of Pu in the entire procedure is about 55%, the analytical results of IAEA soil 6 and IAEA-367 in this work are in a good agreement with the values reported in the literature or reference values, revealing that the developed method for plutonium determination in environmental samples is reliable. The measurement results of (239+240)Pu by alpha spectrometry agreed very well with the sum of (239)Pu and (240)Pu measured by ICP-MS. ICP-MS can not only measure (239)Pu and (240)Pu separately but also (241)Pu. However, it is impossible to measure (238)Pu using ICP-MS in environmental samples even a decontamination factor as high as 10(6) for uranium was obtained by chemical separation. PMID:24401459

  4. A RUNAWAY BLACK HOLE IN COSMOS: GRAVITATIONAL WAVE OR SLINGSHOT RECOIL?

    SciTech Connect

    Civano, F.; Elvis, M.; Lanzuisi, G.; Hao, H.; Aldcroft, T.; Jahnke, K.; Zamorani, G.; Comastri, A.; Bolzonella, M.; Blecha, L.; Loeb, A.; Bongiorno, A.; Brusa, M.; Leauthaud, A.; Mainieri, V.; Piconcelli, E.; Salvato, M.; Scoville, N.; Trump, J.; Vignali, C.

    2010-07-01

    We present a detailed study of a peculiar source detected in the COSMOS survey at z = 0.359. Source CXOC J100043.1+020637, also known as CID-42, has two compact optical sources embedded in the same galaxy. The distance between the two, measured in the HST/ACS image, is 0.''495 {+-} 0.''005 that, at the redshift of the source, corresponds to a projected separation of 2.46 {+-} 0.02 kpc. A large ({approx}1200 km s{sup -1}) velocity offset between the narrow and broad components of H{beta} has been measured in three different optical spectra from the VLT/VIMOS and Magellan/IMACS instruments. CID-42 is also the only X-ray source in COSMOS, having in its X-ray spectra a strong redshifted broad absorption iron line and an iron emission line, drawing an inverted P-Cygni profile. The Chandra and XMM-Newton data show that the absorption line is variable in energy by {Delta}E = 500 eV over four years and that the absorber has to be highly ionized in order not to leave a signature in the soft X-ray spectrum. That these features-the morphology, the velocity offset, and the inverted P-Cygni profile-occur in the same source is unlikely to be a coincidence. We envisage two possible explanations, both exceptional, for this system: (1) a gravitational wave (GW) recoiling black hole (BH), caught 1-10 Myr after merging; or (2) a Type 1/Type 2 system in the same galaxy where the Type 1 is recoiling due to the slingshot effect produced by a triple BH system. The first possibility gives us a candidate GW recoiling BH with both spectroscopic and imaging signatures. In the second case, the X-ray absorption line can be explained as a BAL-like outflow from the foreground nucleus (a Type 2 AGN) at the rearer one (a Type 1 AGN), which illuminates the otherwise undetectable wind, giving us the first opportunity to show that fast winds are present in obscured active galactic nuclei (AGNs), and possibly universal in AGNs.

  5. Isotopic disequilibrium of uranium: alpha-recoil damage and preferential solution effects.

    PubMed

    Fleischer, R L

    1980-02-29

    Preferential loss of uranium-234 relative to uranium-238 from rocks into solutions has long been attributed to recoiling alpha-emitting nuclei. Direct evidence has been obtained for two mechanisms, first, recoil ejection from grains, and now release by natural etching of alpha-recoil tracks. The observations have implications for radon emanation and for the storage of alpha-emitting radioactive waste. PMID:17830457

  6. Recoil ion charge state distribution following the beta(sup +) decay of {sup 21}Na

    SciTech Connect

    Scielzo, Nicholas D.; Freedman, Stuart J.; Fujikawa, Brian K.; Vetter, Paul A.

    2003-01-03

    The charge state distribution following the positron decay of 21Na has been measured, with a larger than expected fraction of the daughter 21Ne in positive charge states. No dependence on either the positron or recoil nucleus energy is observed. The data is compared to a simple model based on the sudden approximation. Calculations suggest a small but important contribution from recoil ionization has important consequences for precision beta decay correlation experiments detecting recoil ions.

  7. (7)Be-recoil radiolabelling of industrially manufactured silica nanoparticles.

    PubMed

    Holzwarth, Uwe; Bellido, Elena; Dalmiglio, Matteo; Kozempel, Jan; Cotogno, Giulio; Gibson, Neil

    2014-01-01

    Radiolabelling of industrially manufactured nanoparticles is useful for nanoparticle dosimetry in biodistribution or cellular uptake studies for hazard and risk assessment. Ideally for such purposes, any chemical processing post production should be avoided as it may change the physico-chemical characteristics of the industrially manufactured species. In many cases, proton irradiation of nanoparticles allows radiolabelling by transmutation of a tiny fraction of their constituent atoms into radionuclides. However, not all types of nanoparticles offer nuclear reactions leading to radionuclides with adequate radiotracer properties. We describe here a process whereby in such cases nanoparticles can be labelled with (7)Be, which exhibits a physical half-life of 53.29 days and emits γ-rays of 478 keV energy, and is suitable for most radiotracer studies. (7)Be is produced via the proton-induced nuclear reaction (7)Li(p,n)(7)Be in a fine-grained lithium compound with which the nanoparticles are mixed. The high recoil energy of (7)Be atoms gives them a range that allows the (7)Be-recoils to be transferred from the lithium compound into the nanoparticles by recoil implantation. The nanoparticles can be recovered from the mixture by dissolving the lithium compound and subsequent filtration or centrifugation. The method has been applied to radiolabel industrially manufactured SiO2 nanoparticles. The process can be controlled in such a way that no alterations of the (7)Be-labelled nanoparticles are detectable by dynamic light scattering, X-ray diffraction and electron microscopy. Moreover, cyclotrons with maximum proton energies of 17-18 MeV that are available in most medical research centres could be used for this purpose. PMID:25285032

  8. Analysis of diacylglycerols by ultra performance liquid chromatography-quadrupole time-of-flight mass spectrometry: Double bond location and isomers separation.

    PubMed

    Deng, Pan; Zhong, Dafang; Wang, Xi; Dai, Yulu; Zhou, Lei; Leng, Ying; Chen, Xiaoyan

    2016-06-21

    Diacylglycerols (DAGs) are important lipid intermediates and have been implicated in human diseases. Isomerism complicates their mass spectrometric analysis; in particular, it is difficult to identify fatty acid substituents and locate the double bond positions in unsaturated DAGs. We have developed an analytical strategy using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC/Q-TOF MS) in conjunction with dimethyl disulfide (DMDS) derivatization and collision cross-section (CCS) measurement to characterize DAGs in biological samples. The method employs non-aqueous reversed-phase chromatographic separation and profile collision energy (CE) mode for MS(E) and MS/MS analyses. Three types of fragment ions were produced simultaneously. Hydrocarbon ions (m/z 50-200) obtained at high CE helped to distinguish unsaturated and saturated DAGs rapidly. Neutral loss ions and acylium ions (m/z 300-400) produced at low CE were used to identify fatty acid substituents. Informative methyl thioalkane fragment ions were used to locate the double bonds of unsaturated DAGs. Mono-methylthio derivatives were formed mainly by the reaction of DAGs with DMDS, where methyl thiol underwent addition to the first double bond farthest from the ester terminus of unsaturated fatty acid chains. The addition of CCS values maximized the separation of isomeric DAG species and improved the confidence of DAG identification. Fourteen DAGs were identified in mouse myotube cells based on accurate masses, characteristic fragment ions, DMDS derivatization, and CCS values. PMID:27188314

  9. B -> D* l nu at zero recoil: an update

    SciTech Connect

    Bailey, Jon A.; Bazavov, A.; Bernard, C.; Bouchard, C.M.; DeTar, C.; El-Khadra, A.X.; Freeland, E.D.; Gamiz, E.; Gottlieb, Steven; Heller, U.M.; Hetrick, J.E.

    2010-11-01

    We present an update of our calculation of the form factor for {bar B} {yields} D*{ell}{bar {nu}} at zero recoil, with higher statistics and finer lattices. As before, we use the Fermilab action for b and c quarks, the asqtad staggered action for light valence quarks, and the MILC ensembles for gluons and light quarks (Luescher-Weisz married to 2+1 rooted staggered sea quarks). In this update, we have reduced the total uncertainty on F(1) from 2.6% to 1.7%.

  10. A Proton Recoil Telescope Detector for Neutron Spectroscopy

    SciTech Connect

    Bocci, F.; Cinausero, M.; Rizzi, V.; Barbui, M.; Prete, G.; Andrighetto, A.; Lunardon, M.; Pesente, S.; Fontana, A.; Gemignian, G.; Bonomi, G.; Donzella, A.; Zenoni, A.; Fabris, D.; Morando, M.; Moretto, S.; Nebbia, G.; Viesti, G.

    2007-10-26

    A compact and versatile Proton Recoil Telescope (PRT) detector has been realized to measure neutron energy spectra in the range from few to hundred MeV. The PRT is a position sensitive detector made by: an active multilayer segmented plastic scintillator as neutron to proton converter, two silicon strip detectors for proton energy and position measurement and a final thick CsI(T1) scintillator to measure the residual proton energy. The detector has been tested with the {sup 13}C(d,n) reaction at Laboratori Nazionali del Sud using a 40 MeV deuteron beam.

  11. Projectile paths corrected for recoil and air resistance

    NASA Astrophysics Data System (ADS)

    Kemp, H. R.

    1986-01-01

    The angle of projection of a bullet is not the same as the angle of the bore of the firearm just before firing. This is because recoil alters the direction of the barrel as the bullet moves along the barrel. Neither is the angle of projection of an arrow the same as the direction of the arrow just before it is projected. The difficulty in obtaining the angle of projection limits the value of the standard equation for trajectories relative to a horizontal plane. Furthermore, air resistance makes this equation unrealistic for all but short ranges.

  12. Filter-Aided N-Glycan Separation (FANGS): A Convenient Sample Preparation Method for Mass Spectrometric N-Glycan Profiling

    PubMed Central

    2014-01-01

    We have developed a simple method for the release and isolation of glycoprotein N-glycans from whole-cell lysates using less than a million cells, for subsequent implementation with mass spectrometric analysis. Cellular protein extracts prepared using SDS solubilization were sequentially treated in a membrane filter device to ultimately release glycans enzymatically using PNGase F in the volatile buffer ammonium bicarbonate. The released glycans are recovered in the filtrate following centrifugation and typically permethylated prior to mass spectrometric analysis. We call our method “filter-aided N-glycan separation” and have successfully applied it to investigate N-glycan profiles of wild-type and mutant Chinese hamster ovary cells. This method is readily multiplexed and, because of the small numbers of cells needed, is compatible with the analysis of replicate samples to assess the true nature of glycan variability in tissue culture samples. PMID:24450425

  13. Determination of ultratrace impurity elements in high purity niobium materials by on-line matrix separation and direct injection/inductively coupled plasma mass spectrometry.

    PubMed

    Kozono, Shuji; Haraguchi, Hiroki

    2007-07-31

    The determination of 52 impurity elements in niobium materials (niobium metal, niobium oxide (V), and niobium pentaethoxide) was performed by inductively coupled plasma mass spectrometry (ICP-MS) with on-line anion exchange matrix separation as well as direct nebulization. Niobium material samples were decomposed with a mixture of hydrofluoric acid and nitric acid to prepare 10% niobium solutions. In the on-line anion exchange matrix separation/ICP-MS, the niobium and hydrofluoric acid concentrations in sample solution were adjusted to 5% and ca. 8M, respectively. The solution was then injected into the carrier stream from the sample loop of injection valve to pass through an anion exchange resin column. In the anion exchange separation, niobium in the fluoro-complex form was adsorbed on the resin, while impurity elements were eluted. The eluted elements were introduced into ICP-MS for the determination of 25 impurity elements. On the other hand, 27 impurity elements could not be separated well from niobium matrix under the above anion exchange conditions, and then the sample solution with the niobium concentration of max. 0.2% containing internal standard elements was injected from the sample loop of injection valve directly to introduce into ICP-MS. As a result, 52 impurity elements in three kinds of niobium materials could be determined at the ng g(-1) level. PMID:19071834

  14. Prompt and delayed spectroscopy of {sup 142}Tb using recoil-isomer tagging

    SciTech Connect

    Mason, P. J. R.; Cullen, D. M.; Kishada, A. M.; Rigby, S. V.; Varley, B. J.; Scholey, C.; Eeckhaudt, S.; Grahn, T.; Greenlees, P. T.; Jakobsson, U.; Jones, P. M.; Julin, R.; Juutinen, S.; Ketelhut, S.; Leino, M.; Leppaenen, A.-P.; Maentyniemi, K.; Nieminen, P.; Nyman, M.; Pakarinen, J.

    2009-02-15

    Recoil-isomer tagging has been used to characterize the states built upon an I{sup {pi}}=8{sup +} isomer in {sup 142}Tb. High-spin states of the neutron-deficient nucleus {sup 142}Tb were populated using an {sup 54}Fe beam, accelerated onto a {sup 92}Mo target of thickness {approx}500 {mu}g/cm{sup 2} at energies of 245, 252, and 265 MeV using the K130 cyclotron at the University of Jyvaeskylae, Finland. Use of the JUROGAM target-position Ge-detector array coupled with the GREAT focal-plane spectrometer at the RITU gas-filled recoil separator has significantly increased the efficiency of the isomer-tagging technique. The rotational band built upon the I{sup {pi}}=8{sup +} isomeric state was established with isomer-tagged {gamma}-{gamma} coincidence data and angular distributions were measured for some of the more intensely populated states. Two previously unobserved bands that bypass the isomer were also established. The new data have been interpreted within the framework of the cranked-shell model. The data show good agreement with the calculated triaxial nuclear shape with {gamma}=-30 deg. for the {sup 142m2}Tb isomeric state. The B(M1)/B(E2) branching ratios, nuclear alignment, signature splitting, and reduced transition probability, B(E1), of the isomeric state have been systematically compared with those of the neighboring nuclei. These comparisons give further evidence for the {pi}h{sub 11/2} x {nu}h{sub 11/2} configuration of the isomer.

  15. Online Matrix Removal Platform for Coupling Gel-Based Separations to Whole Protein Electrospray Ionization Mass Spectrometry

    PubMed Central

    Kim, Ki Hun; Compton, Philip D.; Tran, John C.; Kelleher, Neil L.

    2015-01-01

    A fractionation method called gel-eluted liquid fraction entrapment electrophoresis (GELFrEE) has been used to dramatically increase the number of proteins identified in top-down proteomic workflows; however, the technique involves the use of sodium dodecyl sulfate (SDS), a surfactant that interferes with electrospray ionization. Therefore, an efficient removal of SDS is absolutely required prior to mass analysis. Traditionally, methanol/chloroform precipitation and spin columns have been used, but they lack reproducibility and are difficult to automate. Therefore, we developed an in-line matrix removal platform to enable the direct analysis of samples containing SDS and salts. Only small molecules like SDS permeate a porous membrane and are removed in a manner similar to cross-flow filtration. With this device, near-complete removal of SDS is accomplished within 5 min and proteins are subsequently mobilized into a mass spectrometer. The new platform was optimized for the analysis of GELFrEE fractions enriched for histones extracted from human HeLa cells. All four core histones and their proteoforms were detected in a single spectrum by high-resolution mass spectrometry. The new method versus protein precipitation/resuspension showed 2- to 10-fold improved signal intensities, offering a clear path forward to improve proteome coverage and the efficiency of top-down proteomics. PMID:25836738

  16. IgY14 and SuperMix immunoaffinity separations coupled with liquid chromatography-mass spectrometry for human plasma proteomic biomarker discovery

    SciTech Connect

    Shi, Tujin; Zhou, Jianying; Gritsenko, Marina A.; Hossain, Mahmud; Camp, David G.; Smith, Richard D.; Qian, Weijun

    2012-02-01

    Interest in the application of advanced proteomics technologies to human blood plasma- or serum-based clinical samples for the purpose of discovering disease biomarkers continues to grow; however, the enormous dynamic range of protein concentrations in these types of samples (often >10 orders of magnitude) represents a significant analytical challenge, particularly for detecting low-abundance candidate biomarkers. In response, immunoaffinity separation methods for depleting multiple high- and moderate-abundance proteins have become key tools for enriching low-abundance proteins and enhancing detection of these proteins in plasma proteomics. Herein, we describe IgY14 and tandem IgY14-Supermix separation methods for removing 14 high-abundance and up to 60 moderate-abundance proteins, respectively, from human blood plasma and highlight their utility when combined with liquid chromatography-tandem mass spectrometry for interrogating the human plasma proteome.

  17. Separation and characterization of phenolic compounds from U.S. pecans by liquid chromatography-tandem mass spectrometry.

    PubMed

    Robbins, Katherine S; Ma, Yuanyuan; Wells, M Lenny; Greenspan, Phillip; Pegg, Ronald B

    2014-05-14

    The phenolic acids and proanthocyanidins (PACs) of pecans possess bioactive properties, which might be useful in retarding the onset of and ameliorating the status of certain chronic disease states. There is a general lack of information in the literature regarding such compounds, especially the PACs. Crude phenolic extracts pooled from eight commercially significant cultivars were selected based on their relatively high antioxidant capacities. The pooled extracts were separated via Sephadex LH-20 column chromatography into five ethanolic low-molecular-weight (LMW) fractions and one acetonic high-molecular-weight (HMW) fraction. The preparations were then characterized using RP-HPLC-ESI-MS/MS and diol-phase HPLC-ESI-MS/MS in order to determine the key constituents present in the LMW and HMW fractions, respectively. As previously observed in pecan nutmeat, ellagic acid and (+)-catechin were found to be the major phenolics in the LMW fractions. The last eluting LMW fraction did not contain phenolic acids; rather it possessed PAC monomers and dimers. The HMW fraction comprised a majority of its PACs as dimers; yet, monomers, trimers, tetramers, pentamers, and hexamers were also separated and characterized. PMID:24738776

  18. Differential cross section and recoil polarization measurements for the gamma p to K+ Lambda reaction using CLAS at Jefferson Lab

    SciTech Connect

    McCracken, Michael E.

    2010-02-01

    We present measurements of the differential cross section and Lambda recoil polarization for the gamma p to K+ Lambda reaction made using the CLAS detector at Jefferson Lab. These measurements cover the center-of-mass energy range from 1.62 to 2.84 GeV and a wide range of center-of-mass K+ production angles. Independent analyses were performed using the K+ p pi- and K+ p (missing pi -) final-state topologies; results from these analyses were found to exhibit good agreement. These differential cross section measurements show excellent agreement with previous CLAS and LEPS results and offer increased precision and a 300 MeV increase in energy coverage. The recoil polarization data agree well with previous results and offer a large increase in precision and a 500 MeV extension in energy range. The increased center-of-mass energy range that these data represent will allow for independent study of non-resonant K+ Lambda photoproduction mechanisms at all production angles.

  19. Differential cross section and recoil polarization measurements for the γp→K+Λ reaction using CLAS at Jefferson Lab

    NASA Astrophysics Data System (ADS)

    McCracken, M. E.; Bellis, M.; Meyer, C. A.; Williams, M.; Adhikari, K. P.; Anghinolfi, M.; Ball, J.; Battaglieri, M.; Berman, B. L.; Biselli, A. S.; Branford, D.; Briscoe, W. J.; Brooks, W. K.; Burkert, V. D.; Careccia, S. L.; Carman, D. S.; Cole, P. L.; Collins, P.; Crede, V.; D'Angelo, A.; Daniel, A.; Dashyan, N.; de Vita, R.; de Sanctis, E.; Deur, A.; Dey, B.; Dhamija, S.; Dickson, R.; Djalali, C.; Doughty, D.; Dugger, M.; Dupre, R.; El Alaoui, A.; Eugenio, P.; Fegan, S.; Fradi, A.; Gabrielyan, M. Y.; Giovanetti, K. L.; Girod, F. X.; Goetz, J. T.; Gohn, W.; Gothe, R. W.; Griffioen, K. A.; Guidal, M.; Hafidi, K.; Hakobyanm, H.; Hanretty, C.; Hassall, N.; Hicks, K.; Holtrop, M.; Ilieva, Y.; Ireland, D. G.; Jo, H. S.; Keller, D.; Khandaker, M.; Khetarpal, P.; Kim, W.; Klein, A.; Klein, F. J.; Kubarovsky, V.; Kuleshov, S. V.; Kuznetsov, V.; Livingston, K.; Mayer, M.; McAndrew, J.; McKinnon, B.; Mestayer, M. D.; Mineeva, T.; Mirazita, M.; Mokeev, V.; Moreno, B.; Moriya, K.; Morrison, B.; Moutarde, H.; Munevar, E.; Nadel-Turonski, P.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Osipenko, M.; Ostrovidov, A. I.; Park, K.; Park, S.; Pasyuk, E.; Pereira, S. Anefalos; Perrin, Y.; Pisano, S.; Pogorelko, O.; Pozdniakov, S.; Price, J. W.; Procureur, S.; Prok, Y.; Protopopescu, D.; Quinn, B.; Raue, B. A.; Ricco, G.; Ripani, M.; Ritchie, B. G.; Rosner, G.; Rossi, P.; Sabatié, F.; Saini, M. S.; Salamanca, J.; Schott, D.; Schumacher, R. A.; Seder, E.; Seraydaryan, H.; Sharabian, Y. G.; Sober, D. I.; Sokhan, D.; Stepanyan, S. S.; Stoler, P.; Strauch, S.; Taiuti, M.; Tedeschi, D. J.; Tkachenko, S.; Ungaro, M.; Vernarsky, B.; Vineyard, M. F.; Watts, D.; Voutier, E.; Weinstein, L. B.; Weygand, D. P.; Wood, M. H.; Zana, L.

    2010-02-01

    We present measurements of the differential cross section and Λ recoil polarization for the γp→K+Λ reaction made using the CLAS detector at Jefferson Lab. These measurements cover the center-of-mass energy range from 1.62 to 2.84 GeV and a wide range of center-of-mass K+ production angles. Independent analyses were performed using the K+pπ- and K+p (missing π-) final-state topologies; results from these analyses were found to exhibit good agreement. These differential-cross-section measurements show excellent agreement with previous CLAS and LEPS results and offer increased precision and a 300-MeV increase in energy coverage. The recoil polarization data agree well with previous results and offer a large increase in precision and a 500-MeV extension in energy range. The increased center-of-mass energy range that these data represent will allow for independent study of nonresonant K+Λ photoproduction mechanisms at all production angles.

  20. Separation and identification of phenolic compounds in Bidens pilosa L. by ultra high performance liquid chromatography with quadrupole time-of-flight mass spectrometry.

    PubMed

    Liang, Xianrui; Xu, Qiao

    2016-05-01

    A validated method based on ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry was established to separate and identify phenolic compounds in Bidens pilosa L. Mass spectrometry experiments were performed both in positive and negative ion modes. A total of 35 compounds were detected, and 26 phenolic compounds were unequivocally identified or tentatively assigned based on retention time, maximum UV absorption, molecular formula, and fragments. The ultra high performance liquid chromatography method was validated and showed good linearity (R(2) ≧ 0.9996) over the test range. The limits of detection and quantification were above 0.072 and 0.162 μg/mL, respectively. The relative standard deviations of intraday and interday precision were below 0.3 and 1.6%, respectively. PMID:27004754

  1. Two-dimensional electrophoresis of Arenicola marina extracellular hemoglobin: separation of chains with identical molecular mass but different isoelectric point.

    PubMed

    Slitine, F E; Toulmond, A

    1991-01-01

    1. On the basis of their molecular masses, four types of polypeptides (A, B, C, D) were obtained by SDS-PAGE of the extracellular hemoglobin of the polychaete annelid Arenicola marina. 2. On 2-dimensional polyacrylamide gel electrophoresis, the erythrocruorin dissociated into six different types of polypeptide chains; A1, A2, B1, B2, C and D. 3. A1 and B1 migrate in 2-dimensional electrophoresis at the same position as alpha and beta chains of human hemoglobin. PMID:1814687

  2. The WITCH experiment: Acquiring the first recoil ion spectrum

    NASA Astrophysics Data System (ADS)

    Kozlov, V. Yu.; Beck, M.; Coeck, S.; Delahaye, P.; Friedag, P.; Herbane, M.; Herlert, A.; Kraev, I. S.; Tandecki, M.; Van Gorp, S.; Wauters, F.; Weinheimer, Ch.; Wenander, F.; Zákoucký, D.; Severijns, N.

    2008-10-01

    The standard model of the electroweak interaction describes β-decay in the well-known V-A form. Nevertheless, the most general Hamiltonian of a β-decay includes also other possible interaction types, e.g. scalar (S) and tensor (T) contributions, which are not fully ruled out yet experimentally. The WITCH experiment aims to study a possible admixture of these exotic interaction types in nuclear β-decay by a precise measurement of the shape of the recoil ion energy spectrum. The experimental set-up couples a double Penning trap system and a retardation spectrometer. The set-up is installed in ISOLDE/CERN and was recently shown to be fully operational. The current status of the experiment is presented together with the data acquired during the 2006 campaign, showing the first recoil ion energy spectrum obtained. The data taking procedure and corresponding data acquisition system are described in more detail. Several further technical improvements are briefly reviewed.

  3. Silicon shallow doping by erbium and oxygen recoils implantation

    NASA Astrophysics Data System (ADS)

    Feklistov, K. V.; Cherkov, A. G.; Popov, V. P.

    2016-09-01

    In order to get shallow high doping of Si with optically active complexes ErOn, Er followed by O recoils implantation was realized by means of subsequent Ar+ 250-290 keV implantation with doses 2×1015-1×1016 cm-2 through 50-nm deposited films of Er and then SiO2, accordingly. High Er concentration up to 5×1020 cm-3 to the depth of 10 nm was obtained after implantation. However, about a half of the Er implanted atoms become part of surface SiO2 during post-implantation annealing at 950 °C for 1 h in the N2 ambient under a SiO2 cap. The mechanism of Er segregation into the cap oxide following the moving amorphous-crystalline interface during recrystallization was rejected by the transmission electron microscopy (TEM) analysis. Instead, the other mechanism of immobile Er atoms and redistribution of recoil-implanted O atoms toward cap oxide was proposed. It explains the observed formation of two Er containing phases: Er-Si-O phase with a high O content adjacent to the cap oxide and deeper O depleted Er-Si phase. The correction of heat treatments is proposed in order to avoid the above-mentioned problems.

  4. Differential cross sections and recoil polarizations for the reaction γp→K+Σ0

    DOE PAGESBeta

    Dey, B.; Meyer, C. A.; Bellis, M.; McCracken, M. E.; Williams, M.; Adhikari, K. P.; Aghasyan, M.; Anghinolfi, M.; Ball, J.; Battaglieri, M.; et al

    2010-08-06

    Here, high-statistics measurements of differential cross sections and recoil polarizations for the reactionmore » $$\\gamma p \\rightarrow K^+ \\Sigma^0$$ have been obtained using the CLAS detector at Jefferson Lab. We cover center-of-mass energies ($$\\sqrt{s}$$) from 1.69 to 2.84 GeV, with an extensive coverage in the $K^+$ production angle. Independent measurements were made using the $$K^{+}p\\pi^{-}$$($$\\gamma$$) and $$K^{+}p$$($$\\pi^-,\\gamma$$) final-state topologies, and were found to exhibit good agreement. Our differential cross sections show good agreement with earlier CLAS, SAPHIR and LEPS results, while offering better statistical precision and a 300-MeV increase in $$\\sqrt{s}$$ coverage. Above $$\\sqrt{s} \\approx 2.5$$ GeV, $t$- and $u$-channel Regge scaling behavior can be seen at forward- and backward-angles, respectively. Our recoil polarization ($$P_\\Sigma$$) measurements represent a substantial increase in kinematic coverage and enhanced precision over previous world data. At forward angles we find that $$P_\\Sigma$$ is of the same magnitude but opposite sign as $$P_\\Lambda$$, in agreement with the static SU(6) quark model prediction of $$P_\\Sigma \\approx -P_\\Lambda$$. This expectation is violated in some mid- and backward-angle kinematic regimes, where $$P_\\Sigma$$ and $$P_\\Lambda$$ are of similar magnitudes but also have the same signs. In conjunction with several other meson photoproduction results recently published by CLAS, the present data will help constrain the partial wave analyses being performed to search for missing baryon resonances.« less

  5. Use of liquid chromatography- quadrupole time-of-flight mass spectrometry for enantioselective separation and determination of pyrisoxazole in vegetables, strawberry and soil.

    PubMed

    Qi, Peipei; Yuan, Yuwei; Wang, Zhiwei; Wang, Xiangyun; Xu, Hao; Zhang, Hu; Wang, Qiang; Wang, Xinquan

    2016-06-01

    The present work firstly described the enantio-separation and determination of pyrisoxazole enantiomers in vegetables, strawberry and soil samples by chiral liquid chromatography coupled to quadrupole time-of-flight mass spectrometry (LC-Q-TOF/MS). Pyrisoxazole has two chiral carbon atoms and consists of four stereoisomers. Taking the specific optical rotation measurement and MS analysis data into consideration, the four enantiomers were discriminated as (-)-A, (+)-A, (+)-B and (-)-B corresponding to their elution order under the optimum chromatographic condition. Influences of the mobile phase and column temperature on the enantio-separation selectivity of pyrisoxazole were explored. The perfect baseline separation of pyrisoxazole enantiomers can be achieved within 10min using methanol- water (70:30, v/v) as mobile phase on chiral Lux Cellulose-3 column. The thermodynamic analysis demonstrated that the enantioseparation of (-)-A and (+)-A, (+)-A and (+)-B were enthalpy driven separation, while the enantioseparation of (+)-B and (-)-B was entropy driven separation. Under the optimum method, method validation including matrix effect, linearity, sensitivity and precision were performed. At the spiked concentration of 10, 50 and 100μgkg(-1), the recoveries of the pyrisoxazole enantiomers in cucumber, tomato, pakchoi, pepper and strawberry samples were 64.2-100% (RSD≤14%); While they were relatively higher in soil samples and all around 120% (RSD ≤10%). The limits of detection are in the range from 0.2 to 1.0μgkg(-1) for cucumber, tomato, pakchoi, pepper, strawberry and soil samples. The developed method was then utilized for monitoring the degradation kinetics of pyrisoxazole enantiomers in strawberry under field trials, which provided the environmental behavior data of chiral pyrisoxazole enantiomers and consequently for further health risk assessment of the chiral pesticides. PMID:27133864

  6. A fast and sensitive method for the separation of carotenoids using ultra-high performance supercritical fluid chromatography-mass spectrometry.

    PubMed

    Jumaah, Firas; Plaza, Merichel; Abrahamsson, Victor; Turner, Charlotta; Sandahl, Margareta

    2016-08-01

    In this study, a rapid and sensitive ultra-high performance supercritical fluid chromatography-mass spectrometry (UHPSFC-MS) method has been developed and partially validated for the separation of carotenoids within less than 6 min. Six columns of orthogonal selectivity were examined, and the best separation was obtained by using a 1-aminoanthracene (1-AA) column. The length of polyene chain as well as the number of hydroxyl groups in the structure of the studied carotenoids determines their differences in the physiochemical properties and thus the separation that is achieved on this column. All of the investigated carotenoids were baseline separated with resolution values greater than 1.5. The effects of gradient program, back pressure, and column temperature were studied with respect to chromatographic properties such as retention and selectivity. Electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) were compared in both positive and negative mode, using both direct infusion and hyphenated with UHPSFC. The ESI in positive mode provided the highest response. The coefficient of determination (R (2)) for all calibration curves were greater than 0.998. Limit of detection (LOD) was in the range of 2.6 and 25.2 ng/mL for α-carotene and astaxanthin, respectively, whereas limit of quantification (LOQ) was in the range of 7.8 and 58.0 ng/mL for α-carotene and astaxanthin, respectively. Repeatability and intermediate precision of the developed UHPSFC-MS method were determined and found to be RSD < 3 % and RSD < 6 %, respectively. The method was applied in order to determine carotenoids in supercritical fluid extracts of microalgae and rosehip. Graphical Abstract Ultra-high performance supercritical fluid chromatography-a rapid separation method for the analysis of carotenoids in rosehip and microalgae samples. PMID:27349917

  7. Detection Efficiency of a ToF Spectrometer from Heavy-Ion Elastic Recoil Detection

    SciTech Connect

    Barbara, E. de; Marti, G. V.; Capurro, O. A.; Fimiani, L.; Mingolla, M. G.; Negri, A. E.; Arazi, A.; Figueira, J. M.; Pacheco, A. J.; Martinez Heimann, D.; Carnelli, P. F. F.; Fernandez Niello, J. O.

    2010-08-04

    The detection efficiency of a time-of-flight system based on two micro-channel plates (MCP) time zero detectors plus a conventional silicon surface barrier detector was obtained from heavy ion elastic recoil measurements (this ToF spectrometer is mainly devoted to measurements of total fusion cross section of weakly bound projectiles on different mass-targets systems). In this work we have used beams of {sup 7}Li, {sup 16}O, {sup 32}S and {sup 35}Cl to study the mass region of interest for its application to measurements fusion cross sections in the {sup 6,7}Li+{sup 27}Al systems at energies around and above the Coulomb barrier (0.8V{sub B{<=}}E{<=}2.0V{sub B}). As the efficiency of a ToF spectrometer is strongly dependent on the energy and mass of the detected particles, we have covered a wide range of the scattered particle energies with a high degree of accuracy at the lowest energies. The different experimental efficiency curves obtained in that way were compared with theoretical electronic stopping power curves on carbon foils and were applied.

  8. Comparative proteome analyses of human plasma following in vivo lipopolysaccharide administration using multidimensional separations coupled with tandem mass spectrometry

    SciTech Connect

    Qian, Weijun; Jacobs, Jon M.; Camp, David G.; Monroe, Matthew E.; Moore, Ronald J.; Gritsenko, Marina A.; Calvano, Steven E.; Lowry, Stephen F.; Xiao, Wenzhong; Moldawer, Lyle L.; Davis, Ronald W.; Tompkins, Ronald G.; Smith, Richard D.

    2005-02-05

    There is significant interest in characterization of the human plasma proteome due to its potential for providing biomarkers applicable to clinical diagnosis and treatment and for gaining a better understanding of human diseases. We describe here a strategy for comparative proteome analyses of human plasma, which is applicable to biomarker identifications for various disease states. Multidimensional liquid chromatography-mass spectrometry has been applied to make comparative proteome analyses of plasma samples from an individual prior to and 9 h after lipopolysaccharide (LPS) administration. Peptide peak areas and the number of peptide identifications for each protein were used to evaluate the reproducibility of LC-MS/MS and to compare relative changes in protein concentration between the samples following LPS treatment. A total of 1563 distinct plasma proteins were confidently identified with 26 proteins observed to be significantly increased in concentration following LPS administration, including several known inflammatory response or acute-phase mediators, and thus constitute potential biomarkers for inflammatory response.

  9. Separating climate-induced mass transfers and instrumental effects from tectonic signal in repeated absolute gravity measurements

    NASA Astrophysics Data System (ADS)

    Van Camp, M.; Viron, O.; Avouac, J. P.

    2016-05-01

    We estimate the signature of the climate-induced mass transfers in repeated absolute gravity measurements based on satellite gravimetric measurements from the Gravity Recovery and Climate Experiment (GRACE) mission. We show results at the globe scale and compare them with repeated absolute gravity (AG) time behavior in three zones where AG surveys have been published: Northwestern Europe, Canada, and Tibet. For 10 yearly campaigns, the uncertainties affecting the determination of a linear gravity rate of change range 3-4 nm/s2/a in most cases, in the absence of instrumental artifacts. The results are consistent with what is observed for long-term repeated campaigns. We also discuss the possible artifact that can result from using short AG survey to determine the tectonic effects in a zone of high hydrological variability. We call into question the tectonic interpretation of several gravity changes reported from stations in Tibet, in particular the variation observed prior to the 2015 Gorkha earthquake.

  10. A novel positively charged achiral co-monomer for β-cyclodextrin monolithic stationary phase: Improved chiral separation of acidic compounds using capillary electrochromatography coupled to mass spectrometry

    PubMed Central

    Bragg, William; Shamsi, Shahab A.

    2013-01-01

    The work presented here demonstrates the incorporation of vinylbenzyl trimethylammonium (VBTA) as a novel positively charged achiral co-monomer to a glycidyl methacrylate-beta cyclodextrin (GMA/β-CD) based monolith, providing anion exchange sites with reversed electroosmotic flow (EOF) for capillary electrochromatography (CEC). The monolithic phases, GMA/β-CD-VBTA and GMA/β-CD (without co-monomer) were characterized by scanning electron microscopy, optical microscopy, pressure drop/flow-rate curves and nitrogen adsorption analysis. After optimizing the stationary phase and mobile phase parameters, chiral separations of 41 pairs of structurally diverse anionic chiral analytes were compared individually using the GMA/β-CD-VBTA and GMA/β-CD monolithic columns. The GMA/β-CD-VBTA monolith chiral stationary phase separated significantly more acidic compounds compared to the GMA/β-CD column. To-date there has been limited work in the development of chiral monolithic column for CEC-mass spectrometry (MS). Because of good electrodriven flow characteristics, which allow the column to maintain a stable current in the absence of outlet vial, GMA/β-CD-VBTA column was successfully coupled to single quadrupole mass spectrometer for CEC-MS of several chiral test compounds. In addition, the same monolithic CEC column when coupled to a triple quadrupole MS instrument, two orders of magnitude higher sensitivity was observed compared to a single quadrupole MS instrument. PMID:23062876

  11. A new method for the separation of different types of nematocysts from scyphozoa and investigation of proteinaceous toxins utilizing laser catapulting and subsequent mass spectrometry.

    PubMed

    Wiebring, Annika; Helmholz, Heike; Sötje, Ilka; Lassen, Stephan; Prange, Andreas; Tiemann, Henry

    2010-06-01

    Jellyfish have an increasing impact on marine ecology. Cnidocysts bearing stinging cells afford, amongst others, prey capture and defence. Several different types of stinging capsules are found in one species and they are supposed to have specific functions, e.g. paralysing prey or adhering to it. Due to these assumed different roles of the capsules, it is suggested that toxins, which are contained in the capsules, differ in composition. Analysis of distinct types of nematocysts requires an appropriate method for the separation of the different types. Mixtures of types of nematocysts were obtained of two species of jellyfish, Aurelia aurita and Cyanea lamarckii, by maceration of the tissue. These mixtures were treated with a method called laser microdissection and pressure catapulting (LMPC). Optimized maceration methods, which were firstly introduced as a method for this purpose, in conjunction with optimized LMPC parameters lead to sufficient amounts of separated capsules of individual types for subsequent mass-spectrometric analyses. In case of A. aurita, the resulting mass spectra had some constituents in common, whereas in the overall pattern, the two distinct nematocyst types differed. PMID:20336340

  12. Rapid chiral separation of atenolol, metoprolol, propranolol and the zwitterionic metoprolol acid using supercritical fluid chromatography-tandem mass spectrometry - Application to wetland microcosms.

    PubMed

    Svan, Alfred; Hedeland, Mikael; Arvidsson, Torbjörn; Jasper, Justin T; Sedlak, David L; Pettersson, Curt E

    2015-08-28

    A method for enantiomeric separation of the three β-blocking agents atenolol, metoprolol, propranolol and the zwitterionic metoprolol acid, a major metabolite of both metoprolol and in environmental matrices also atenolol, has been developed. By use of supercritical fluid chromatography and the polysaccharide-based Chiralpak(®) IB-3, all four compounds were simultaneously enantiomerically separated (Rs>1.5) within 8min. Detection was performed using tandem mass spectrometry, and to avoid isobaric interference between the co-eluting metoprolol and metoprolol acid, the achiral column Acquity(®) UPC(2) BEH 2-EP was attached ahead of to the chiral column. Carbon dioxide with 18% methanol containing 0.5% (v/v) of the additives trifluoroacetic acid and ammonia in a 2:1 molar ratio were used as mobile phase. A post column make-up flow (0.3mL/min) of methanol containing 0.1% (v/v) formic acid was used to enhance the positive electrospray ionization. Detection was carried out using a triple quadrupole mass spectrometer operating in the selected reaction monitoring mode, using one transition per analyte and internal standard. The method was successfully applied for monitoring the enantiomeric fraction change over time in a laboratory scale wetland degradation study. It showed good precision, recovery, sensitivity and low effect of the sample matrix. PMID:26228849

  13. Heat-transfer and pressure distributions for laminar separated flows downstream of rearward-facing steps with and without mass suction

    NASA Technical Reports Server (NTRS)

    Brown, R. D.; Jakubowski, A. K.

    1974-01-01

    Heat-transfer and pressure distributions were measured for laminar separated flows downstream of rearward-facing steps with and without mass suction. The flow conditions were such that the boundary-layer thickness was comparable to or larger than the step height. For both suction and no-suction cases, an increase in the step height resulted in a sharp decrease in the initial heat-transfer rates behind the step. Downstream, however, the heat transfer gradually recovered back to less than or near attached-flow values. Mass suction from the step base area increased the local heat-transfer rates; however, this effect was relatively weak for the laminar flows considered. Even removal of the entire approaching boundary layer raised the post-step heat-transfer rates only about 10 percent above the flatplate values. Post-step pressure distributions were found to depend on the entrainment conditions at separation. In the case of the solid-faced step, a sharp pressure drop behind the step was followed by a very short plateau and relatively fast recompression. For the slotted-step connected to a large plenum but without suction, the pressure drop at the base was much smaller and the downstream recompression more gradual than that for solid-faced step.

  14. Structural characterization of synthetic polymers and copolymers using multidimensional mass spectrometry interfaced with thermal degradation, liquid chromatography and/or ion mobility separation

    NASA Astrophysics Data System (ADS)

    Alawani, Nadrah

    This dissertation focuses on coupling mass spectrometry (MS) and tandem mass spectrometry (MS/MS) to thermal degradation, liquid chromatography (LC) and/or ion mobility (IM) spectrometry for the characterization of complex mixtures. In chapter II, an introduction of the history and the principles of MS and LC are discussed. Chapter III illustrates the materials and instrumentation used to complete this dissertation. Polyethers have been characterized utilizing MS/MS, as presented in Chapter IV and Chapter VI. Diblock copolymers of polyethylene oxide and polycaprolactone, PEO-b-PCL, have been characterized by matrix-assisted laser desorption/ionization quadrupole/time-of-flight mass spectrometry (MALDI-Q/ToF) and LC-MS/MS (Chapter V). Thermoplastic elastomers have been characterized by thermal degradation using an atmospheric solids analysis probe (ASAP) and ion mobility mass spectrometry (IM-MS), as discussed in Chapter VII. Interfacing separation techniques with mass spectrometry permitted the detection of species present with low concentration in complex materials and improved the sensitivity of MS. In chapter IV, the fragmentation mechanisms in MS/MS experiments of cyclic and linear poly(ethylene oxide) macroinitiators are discussed. This study aimed at determining the influence of end groups on the fragmentation pathways. In the study reported in Chapter V, ultra high performance liquid chromatography (UHPLC) was interfaced with MS and MS/MS to achieve the separation and in-depth characterization and separation of amphiphilic diblock copolymers (PEO- b-PCL) in which the architecture of the PEO block is linear or cyclic. Applying UPLC-MS and UPLC-MS/MS provides fast accurate information about the number and type of the blocks in the copolymers. Chapter VI reports MS/MS and IM-MS analyses which were performed to elucidate the influence of molecular size and collision energy on the fragmentation pathways of polyethers subjected to collisionally activated

  15. Electrochemically modulated separation, concentration, and detection of plutonium using an anodized glassy carbon electrode and inductively coupled plasma mass spectrometry.

    PubMed

    Clark, William J; Park, Sea H; Bostick, Debra A; Duckworth, Douglas C; Van Berkel, Gary J

    2006-12-15

    Plutonium is shown to be retained on anodized glassy carbon (GC) electrodes at potentials positive of +0.7 V (vs Ag/AgCl reference) and released upon potential shifts to values negative of +0.3 V. This phenomenon has been exploited for the separation, concentration, and detection of plutonium by the coupling an electrochemical flow cell on-line with an ICPMS system. The electrochemically controlled deposition and analysis of Pu improves detection limits by analyte preconcentration and by matrix and isobaric ion elimination. Information related to the parametric optimization of the technique and hypotheses regarding the mechanism of electrochemical accumulation of Pu are reported. The most likely accumulation scenario involves complexation of Pu(IV) species, produced under a controlled potential, with anions retained in the anodization film that develops during the activation of the GC electrode. The release mechanism is believed to result from the reduction of Pu(IV) in the anion complex to Pu(III), which has a lower tendency to form complexes. PMID:17165850

  16. Electrochemically Modulated Separation, Concentration, and Detection of Plutonium Using an Anodized Glassy Carbon Electrode and Inductively Coupled Plasma Mass Spectrometry

    SciTech Connect

    Clark, William J.; Park, Sea H.; Bostick, Debra A.; Duckworth, Doug C.; Van Berkel, Gary J.

    2006-12-15

    Plutonium is shown to be retained on anodized glassy carbon (GC) electrodes at potentials positive of +0.7 V (vs. Ag/AgCl reference) and released upon potential shifts to values negative of +0.3 V. This phenomenon has been exploited for the separation, concentration, and detection of plutonium by the coupling an electrochemical flow cell online with an ICP-MS system. The electrochemically-controlled deposition and analysis of Pu improves detection limits by analyte preconcentration and by matrix and isobaric ion elimination. Information related to the parametric optimization of the technique and hypotheses regarding the mechanism of electrochemical accumulation of Pu are reported. The most likely accumulation scenario involves complexation of Pu (IV) species, produced under a controlled potential, with anions retained in the anodization film that develops during the activation of the GC electrode. The release mechanism is believed to result from the reduction of Pu(IV) in the anion complex to Pu (III), which has a lower tendency to form complexes.

  17. Separation of cellular nonpolar neutral lipids by normal-phase chromatography and analysis by electrospray ionization mass spectrometry

    PubMed Central

    Hutchins, Patrick M.; Barkley, Robert M.; Murphy, Robert C.

    2008-01-01

    Neutral lipids are an important class of hydrophobic compounds found in all cells that play critical roles from energy storage to signal transduction. Several distinct structural families make up this class, and within each family there are numbers of individual molecular species. A solvent extraction protocol has been developed to efficiently isolate neutral lipids without complete extraction of more polar phospholipids. Normal-phase HPLC was used for the separation of cholesteryl esters (CEs), monoalkylether diacylglycerols, triacylglycerols, and diacylglycerols in a single HPLC run from this extract. Furthermore, minor lipids such as ubiquinone-9 could be detected in RAW 264.7 cells. Molecular species that make up each neutral lipid class can be analyzed both qualitatively and quantitatively by on-line LC-MS and LC-MS/MS strategies. The quantitation of >20 CE molecular species revealed that challenging RAW 264.7 cells with a Toll-like receptor 4 agonist caused a >20-fold increase in the content of CEs within cells, particularly those CE molecular species that contained saturated (14:0, 16:0, and 18:1) fatty acyl groups. Longer chain CE molecular species did not change in response to the activation of these cells. PMID:18223242

  18. Characterization of Diesel Fuel by Chemical Separation Combined with Capillary Gas Chromatography (GC) Isotope Ratio Mass Spectrometry (IRMS)

    SciTech Connect

    Harvey, Scott D.; Jarman, Kristin H.; Moran, James J.; Sorensen, Christina M.; Wright, Bob W.

    2011-09-15

    The purpose of this study was to perform a preliminary investigation of compound-specific isotope analysis (CSIA) of diesel fuels to evaluate whether the technique could distinguish between the diesel samples from different sources/locations. The ability to differentiate or correlate diesel samples could be valuable for detecting fuel tax evasion schemes. Two fractionation techniques were used to isolate the n-alkanes from the fuel. Both δ13C and δD values for the n-alkanes were then determined by CSIA in each sample. Plots of δD versus δ13C with sample n-alkane points connected in order of increasing carbon number gave well separated clusters with characteristic shapes for each sample. Principal components analysis (PCA) with δ13C, δD, or combined δ13C and δD data on the yielded scores plots that could clearly differentiate the samples, thereby demonstrating the potential of this approach for fingerprinting fuel samples using the δ13C and δD values.

  19. Gadolinium speciation with Tetradentate, N-donor extractants for minor actinide/lanthanide separation: an XRD, mass spectrometry and EPR study

    SciTech Connect

    Whittaker, D.M.; Sharrad, C.A.; Sproules, S.

    2013-07-01

    The hydrophobic organic molecules CyMe{sub 4}-BTPhen (1) and CyMe{sub 4}-BTBP (2) have been developed and tuned over many years to be able to separate the trivalent actinides from the trivalent lanthanides (Ln) selectively in bi-phasic solvent extraction processes for the separation of the long-lived radio-toxic minor actinides from spent nuclear fuel. The ability of these N-donor ligands to perform this separation is poorly understood, as is their speciation with the metal ions when extracted into the organic phase. Our previous work has shown Ln{sup 3+} speciation to be largely 1:2 Ln:L in nature with another small molecule, either water or nitrate, occupying a cavity between the tetradentate bound N-donor ligands. The identity of the small molecule changes across the lanthanide series, and here we continue investigations into this speciation. Complexes of these N-donor ligands with Gd{sup 3+} have been synthesised and characterised by X-ray crystallography, mass spectrometry and EPR spectroscopy. We show that the N-donor ligands have no effect on the electronic configuration of Gd{sup 3+} and that the lanthanide contraction with the steric rigidity of the N-donor ligand appears to determine the size of the cavity between the coordinated ligands. This in turn appears to control the identity of the small molecule on the ninth site in the 1:2 Gd:L species. (authors)

  20. Target-guided separation of Bougainvillea glabra betacyanins by direct coupling of preparative ion-pair high-speed countercurrent chromatography and electrospray ionization mass-spectrometry.

    PubMed

    Jerz, Gerold; Wybraniec, Sławomir; Gebers, Nadine; Winterhalter, Peter

    2010-07-01

    In this study, preparative ion-pair high-speed countercurrent chromatography was directly coupled to an electrospray ionization mass-spectrometry device (IP-HSCCC/ESI-MS-MS) for target-guided fractionation of high molecular weight acyl-oligosaccharide linked betacyanins from purple bracts of Bougainvillea glabra (Nyctaginaceae). The direct identification of six principal acyl-oligosaccharide linked betacyanins in the mass range between m/z 859 and m/z 1359 was achieved by positive ESI-MS ionization and gave access to the genuine pigment profile already during the proceeding of the preparative separation. Inclusively, all MS/MS-fragmentation data were provided during the chromatographic run for a complete analysis of substitution pattern. On-line purity evaluation of the recovered fractions is of high value in target-guided screening procedures and for immediate decisions about suitable fractions used for further structural analysis. The applied preparative hyphenation was shown to be a versatile screening method for on-line monitoring of countercurrent chromatographic separations of polar crude pigment extracts and also traced some minor concentrated compounds. For the separation of 760mg crude pigment extract the biphasic solvent system tert.-butylmethylether/n-butanol/acetonitrile/water 2:2:1:5 (v/v/v/v) was used with addition of ion-pair forming reagent trifluoroacetic acid. The preparative HSCCC-eluate had to be modified by post-column addition of a make-up solvent stream containing formic acid to reduce ion-suppression caused by trifluoroacetic acid and later significantly maximized response of ESI-MS/MS detection of target substances. A variable low-pressure split-unit guided a micro-eluate to the ESI-MS-interface for sensitive and direct on-line detection, and the major volume of the effluent stream was directed to the fraction collector for preparative sample recovery. The applied make-up solvent mixture significantly improved smoothness of the continuously

  1. Associations of adult separation anxiety disorder with conflict-related trauma, ongoing adversity, and the psychosocial disruptions of mass conflict among West Papuan refugees.

    PubMed

    Tay, Alvin Kuowei; Rees, Susan; Kareth, Moses; Silove, Derrick

    2016-03-01

    Refugees commonly experience traumatic events that threaten the self and close others, suggesting the possibility that they may experience overlapping symptoms of posttraumatic stress disorder (PTSD) and separation anxiety disorder (SAD). We examine this possibility among West Papua refugees (n = 230) displaced to Port Moresby, Papua New Guinea. We also examine associations between the combined PTSD-SAD construct and indices of past trauma exposure, ongoing adversity, and the psychosocial disruptions caused by mass conflict and displacement. We applied culturally adapted interview modules to assess symptoms of PTSD, SAD, traumatic events (TEs), ongoing adversity, and 5 psychosocial dimensions. Latent class analysis identified a PTSD class (23%), a posttraumatic (PT) SAD class (22%), and a low-symptom class (55%). Compared with the low-symptom class, both the PTSD and PT-SAD classes endorsed higher levels of exposure to all domains of TEs (conflict-related trauma, witnessing murder, childhood related adversities, traumatic losses, and health stress) and ongoing adversity (access to health care, displacement/separation, safety in the community, and access to basic needs), but the 2 comorbid groups did not differ on these indices. The PT-SAD class alone scored higher than the low-symptom reference class in relation to disruptions to the psychosocial domains (safety/security, bonds/network, access to justice, roles/identities, existential meaning) and higher than the PTSD class on safety/security, justice and roles/identities. Our findings suggest that the PT-SAD pattern may represent a response to the most severe forms of psychosocial disruptions of mass conflict among refugees. A focus on separation anxiety may enhance psychotherapies designed to treat PTSD in refugees. (PsycINFO Database Record PMID:26752442

  2. Comparative Proteome Analyses of Human Plasma Following in vivo Lipopolysaccharide Administration Using Multidimensional Separations Coupled with Tandem Mass Spectrometry

    SciTech Connect

    Qian, Weijun; Jacobs, Jon M.; Camp, David G.; Monroe, Matthew E.; Moore, Ronald J.; Gritsenko, Marina A.; Calvano, Steven E.; Lowry, Stephen F.; Xiao, Wenzhong; Moldawer, Lyle L.; Davis, Ronald W.; Tompkins, Ronald G.; Smith, Richard D.

    2005-01-03

    There is significant interest in characterization of the human plasma proteome due to its potential for providing biomarkers applicable to clinical diagnosis and treatment and for gaining a better understanding of human diseases. We describe here a strategy for comparative proteome analyses of human plasma, which is applicable to biomarker identifications for various disease states. Multidimensional liquid chromatography-mass spectrometry has been applied to make comparative proteome analyses of plasma samples from an individual prior to and 9 h after lipopolysaccharide (LPS) administration. Peptide peak areas and the number of peptide identifications for each protein were used to evaluate the reproducibility of LC-MS/MS and to compare relative changes in protein concentration between the samples following LPS treatment. A total of 804 distinct plasma proteins (not including immunoglobulins) were confidently identified with 32 proteins observed to be significantly increased in concentration following LPS administration, including several known inflammatory response or acute-phase mediators such as C-reactive protein, serum amyloid A and A2, LPS-binding protein, LPS-responsive and beige-like anchor protein, hepatocyte growth factor activator and von Willebrand factor, and thus constituting potential biomarkers for inflammatory response.

  3. Deconvoluting nonaxial recoil in Coulomb explosion measurements of molecular axis alignment

    NASA Astrophysics Data System (ADS)

    Christensen, Lauge; Christiansen, Lars; Shepperson, Benjamin; Stapelfeldt, Henrik

    2016-08-01

    We report a quantitative study of the effect of nonaxial recoil during Coulomb explosion of laser-aligned molecules and introduce a method to remove the blurring caused by nonaxial recoil in the fragment-ion angular distributions. Simulations show that nonaxial recoil affects correlations between the emission directions of fragment ions differently from the effect caused by imperfect molecular alignment. The method, based on analysis of the correlation between the emission directions of the fragment ions from Coulomb explosion, is used to deconvolute the effect of nonaxial recoil from experimental fragment angular distributions. The deconvolution method is then applied to a number of experimental data sets to correct the degree of alignment for nonaxial recoil, to select optimal Coulomb explosion channels for probing molecular alignment, and to estimate the highest degree of alignment that can be observed from selected Coulomb explosion channels.

  4. Electron recombination in low-energy nuclear recoils tracks in liquid argon

    NASA Astrophysics Data System (ADS)

    Wojcik, M.

    2016-02-01

    This paper presents an analysis of electron-ion recombination processes in ionization tracks of recoiled atoms in liquid argon (LAr) detectors. The analysis is based on the results of computer simulations which use realistic models of electron transport and reactions. The calculations reproduce the recent experimental results of the ionization yield from 6.7 keV nuclear recoils in LAr. The statistical distribution of the number of electrons that escape recombination is found to deviate from the binomial distribution, and estimates of recombination fluctuations for nuclear recoils tracks are obtained. A study of the recombination kinetics shows that a significant part of electrons undergo very fast static recombination, an effect that may be responsible for the weak drift-field dependence of the ionization yield from nuclear recoils in some noble liquids. The obtained results can be useful in the search for hypothetical dark matter particles and in other studies that involve detection of recoiled nuclei.

  5. Developing the Recoil Distance Doppler-Shift technique towards a versatile tool for lifetime measurements of excited nuclear states

    NASA Astrophysics Data System (ADS)

    Dewald, A.; Möller, O.; Petkov, P.

    2012-07-01

    In this article, the Recoil Distance Doppler-Shift (RDDS) method which is extensively used in nuclear structure physics to determine level lifetimes and absolute transition probabilities is reviewed. Especially, it is aimed to present new developments and variants of the technique which have evolved mainly in the past 25 years. After a short and comprehensive description of the basic elements of the plunger technique, the new variants are presented. This comprises the RDDS technique using γγ-coincidences, RDDS measurements in combination with particle detectors for selecting specific reaction channels, RDDS after Coulomb excitation, RDDS after fission and RDDS using a gas target. In addition, the concept of a differential plunger is discussed with respect to its specific features and typical experimental setups. Examples of differential plunger measurements with recoil tagging, recoil decay tagging and after deep inelastic reactions, Coulomb excitation in inverse reaction kinematics as well as after reactions with fast radioactive beams at energies of 50-100 MeV/u are given. The second focus of the review is dedicated to today’s plunger devices and related hardware. The concepts of specific plunger devices which accommodate the specific demands of the aforementioned RDDS applications including specific feedback systems for controlling target-stopper/degrader separations in-beam are presented. Also discussed are target and stopper/degrader foil related issues like foil preparation, mounting and stretching as well as specific features of the foil behavior in-beam (temperature, blistering, wrinkling and carbon build-up). The third focus is devoted to the data analysis. The concept of the Differential Decay Curve Method (DDCM) is presented as an alternative approach for the analysis of RDDS data measured as singles or as γγ-coincidences. For the latter, different gating possibilities are discussed, e.g. gating from above and gating from below the level of

  6. Optimization of separation and detection conditions for the multiresidue analysis of pesticides in grapes by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry.

    PubMed

    Banerjee, Kaushik; Patil, Sangram H; Dasgupta, Soma; Oulkar, Dasharath P; Patil, Shubhangi B; Savant, Rahul; Adsule, Pandurang G

    2008-05-01

    A comprehensive GCxGC-TOFMS method was optimized for multiresidue analysis of pesticides using a combination of a non-polar (RTX-5MS, 10 m x 0.18 mm x 0.2 microm) and a polar capillary column (TR-50MS, 1 m x 0.1 mm x 0.1 microm), connected in series through a dual stage thermal modulator. The method resolved the co-elution problems as observed in full scan one-dimensional GC-MS analysis and allowed chromatographic separation of 51 pesticides within 24 min run time with library-searchable mass spectrometric confirmation. Four pesticides, viz. chlorpyrifos-methyl, vinclozoline, parathion-methyl and heptachlor could be baseline separated on GCxGC, which were otherwise closely eluting and interfering each other's detection in 1D GC-MS run. Similarly, it could be possible to separate myclobutanil, buprofezin, flusilazole and oxyfluorfen on GCxGC. Although in 1D GC-MS, these closely eluting compounds could be identified through deconvolution algorithm and 'peak-find' option of the Chromatof software but the spectral purity significantly improved on GCxGC analysis. Thorough optimization was accomplished for the oven temperature programming, ion source temperature and GCxGC parameters like modulation period, duration of hot pulses, modulation-offset temperature, acquisition rate, etc. to achieve best possible separation of the test compounds. The limit of detection significantly improved by 2-12 times on GCxGC-TOFMS against GC-TOFMS because of sharper and narrower peak shapes. The method was tested for grape matrix after preparing the samples using previously described method and recoveries of the entire test pesticides were within 70-110% at 10 ng/g level of fortification. GCxGC-TOFMS was found to be an excellent technique for library-based screening of pesticides with high accuracy and sensitivity. PMID:18371973

  7. Advancement in stationary phase for peptide separation helps in protein identification: application to atheroma plaque proteomics using nano-chip liquid chromatography and mass spectrometry.

    PubMed

    Delporte, Cédric; Noyon, Caroline; Raynal, Pierre; Dufour, Damien; Nève, Jean; Abts, Frederic; Haex, Martin; Zouaoui Boudjeltia, Karim; Van Antwerpen, Pierre

    2015-03-13

    In the last decades, proteomics has largely progressed. Mass spectrometry and liquid chromatography (LC) are generally used in proteomics. These techniques enable proper separation of peptides and good identification and/or quantification of them. Later, nano-scaled liquid chromatography, improvements of mass spectrometry resolution and sensitivity brought huge advancements. Enhancements in chemistry of chromatographic columns also brought interesting results. In the present work, the potency of identification of proteins by different nano-chip columns was studied and compared with classical LC column. The present study was applied to cardiovascular field where proteomics has shown to be highly helpful in research of new biomarkers. Protein extracts from atheroma plaques were used and proteomics data were compared. Results show that fewer spectra were acquired by the mass spectrometer when nano-chip columns were used instead of the classical ones. However, approximately 40% more unique peptides were identified by the recently optimized chip named Polaris-HR-chip-3C18 column, and 20% more proteins were identified. This fact leads to the identification of more low-abundance proteins. Many of them are involved in atheroma plaque development such as apolipoproteins, ceruloplasmin, etc. In conclusion, present data shows that recent developments of nanoLC column chemistry and dimensions enabled the improved detection and identification of low-abundance proteins in atheroma plaques. Several of them are of major interest in the field of cardiovascular disease. PMID:25680550

  8. Separating Autotrophic and Heterotrophic Contributions to Soil Respiration in Maize-Based Agroecosystems Using Stable Carbon Isotope Ratio Mass Spectrometry.

    NASA Astrophysics Data System (ADS)

    Amos, B.; Walters, D. T.; Madhavan, S.; Arkebauer, T. J.; Scoby, D. L.

    2005-12-01

    Any effort to establish a carbon budget for a growing crop by means of a thorough accounting of all C sources and sinks will require the ability to discriminate between autotrophic and heterotrophic contributions to soil surface CO2 flux. Autotrophic soil respiration (Ra) is defined as combined root respiration and the respiration of soil microorganisms residing in the rhizosphere and using root-derived carbohydrates as an energy source, while heterotrophic respiration (Rh) is defined as the respiration of soil microorganisms and macroorganisms not directly under the influence of the live root system and using SOM as an energy source. We partition soil surface CO2 flux into its autotrophic and heterotrophic components by combining root exclusion with stable carbon isotope techniques in production scale (~65 ha) maize-based agroecosystems. After flux measurements, small chambers are placed on collars in both root excluded shields and in non-root excluded soil, ambient headspace CO2 is removed using a soda lime trap, and soil-respired C is allowed to collect in the chambers. Soil respiration samples are then collected in 12mL evacuated exetainers and analyzed for δ13C by means of a Finnigan Delta-S isotope ratio mass spectrometer interfaced with a Thermo Finnigan GasBench II and a cryogenic trap to increase CO2 concentration. These δ13C measurements were made throughout the 2005 growing season in maize fields representing three agroecosystems: irrigated continuous maize, irrigated maize-soybean rotation, and rainfed maize soybean rotation. Estimates of autotrophic and heterotrophic soil respiration along with other results of this study will be presented.

  9. A rapid method for the separation of vitamin D and its metabolites by ultra-high performance supercritical fluid chromatography-mass spectrometry.

    PubMed

    Jumaah, Firas; Larsson, Sara; Essén, Sofia; Cunico, Larissa P; Holm, Cecilia; Turner, Charlotta; Sandahl, Margareta

    2016-04-01

    In this study, a new supercritical fluid chromatography-mass spectrometry (SFC-MS) method has been developed for the separation of nine vitamin D metabolites within less than eight minutes. This is the first study of analysis of vitamin D and its metabolites carried out by SFC-MS. Six columns of orthogonal selectivity were examined, and the best separation was obtained by using a 1-aminoanthracene (1-AA) column. The number and the position of hydroxyl groups in the structure of the studied compounds as well as the number of unsaturated bonds determine the physiochemical properties and, thus the separation of vitamin D metabolites that is achieved on this column. All D2 and the D3 forms were baseline separated with resolution values>1.5. The effects of pressure, temperature, flow rate and different gradient modes were studied. Electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) were compared in positive mode, both by direct infusion and after SFC separation. The results showed that the sensitivity in APCI(+) was higher than in ESI(+) using direct infusion. In contrast, the sensitivity in APCI(+) was 6-fold lower than in ESI(+) after SFC separation. The SFC-MS method was validated between 10 and 500ng/mL for all analytes with coefficient of determination (R(2))≥0.999 for all calibration curves. The limits of detection (LOD) were found to range between 0.39 and 5.98ng/mL for 24,25-dihydroxyvitamin D3 (24,25(OH)2D3) and 1-hydroxyvitamin D2 (1OHD2), respectively. To show its potential, the method was applied to human plasma samples from healthy individuals. Vitamin D3 (D3), 25-hydroxyvitamin D3 (25OHD3) and 24,25(OH)2D3 were determined in plasma samples and the concentrations were 6.6±3.0ng/mL, 23.8±9.2ng/mL and 5.4±2.7ng/mL, respectively. PMID:26931428

  10. Dielectric barrier structure with hollow electrodes and its recoil effect

    SciTech Connect

    Yu, Shuang; Chen, Qunzhi; Liu, Jiahui; Wang, Kaile; Jiang, Zhe; Sun, Zhili; Zhang, Jue; Fang, Jing

    2015-06-15

    A dielectric barrier structure with hollow electrodes (HEDBS), in which gas flow oriented parallel to the electric field, was proposed. Results showed that with this structure, air can be effectively ignited, forming atmospheric low temperature plasma, and the proposed HEDBS could achieve much higher electron density (5 × 10{sup 15}/cm{sup 3}). It was also found that the flow condition, including outlet diameter and flow rate, played a key role in the evolution of electron density. Optical emission spectroscopy diagnostic results showed that the concentration of reactive species had the same variation trend as the electron density. The simulated distribution of discharge gas flow indicated that the HEDBS had a strong recoil effect on discharge gas, and could efficiently promote generating electron density as well as reactive species.

  11. B{yields}D* at zero recoil revisited

    SciTech Connect

    Gambino, Paolo; Mannel, Thomas; Uraltsev, Nikolai

    2010-06-01

    We examine the B{yields}D* form factor at zero recoil using a continuum QCD approach rooted in the heavy quark sum rules framework. A refined evaluation of the radiative corrections as well as the most recent estimates of higher-order power terms together with more careful continuum calculation are included. An upper bound on the form factor of F(1) < or approx. 0.93 is derived, based on just the positivity of inelastic contributions. A model-independent estimate of the inelastic contributions shows they are quite significant, lowering the form factor by about 6% or more. This results in an unbiased estimate F(1){approx_equal}0.86 with about 3% uncertainty in the central value.

  12. Proton recoil spectroscopy 400 meters from a fission neutron source

    SciTech Connect

    Stanka, M.B.

    1994-12-31

    Neutron kerma and spectrum measurements have been made at the US Army Pulse Radiation Facility (APRF) to 400m in an air-over-ground geometry from a fission neutron source and have been compared to Monte Carlo transport calculations. The neutron spectra measurements were made using a rotating neutron spectrometer. This spectrometer consists of four spherical proton-recoil detectors mounted on a common rotating base. Detector radius, gas composition, and pressure have been varied to allow sensitivity over a neutron range of 50 keV to 4.5 MeV. Neutron kerma was determined by using the Kerr soft-tissue kerma factors. Measured neutron kerma agreed with the calculated neutron kerma to within 5%. Comparisons with other neutron spectrometers such as NE213 and Bonner Spheres are presented and agreement between the different spectrometers is better than 20%.

  13. Calibration of a compact magnetic proton recoil neutron spectrometer

    NASA Astrophysics Data System (ADS)

    Zhang, Jianfu; Ouyang, Xiaoping; Zhang, Xianpeng; Ruan, Jinlu; Zhang, Guoguang; Zhang, Xiaodong; Qiu, Suizheng; Chen, Liang; Liu, Jinliang; Song, Jiwen; Liu, Linyue; Yang, Shaohua

    2016-04-01

    Magnetic proton recoil (MPR) neutron spectrometer is considered as a powerful instrument to measure deuterium-tritium (DT) neutron spectrum, as it is currently used in inertial confinement fusion facilities and large Tokamak devices. The energy resolution (ER) and neutron detection efficiency (NDE) are the two most important parameters to characterize a neutron spectrometer. In this work, the ER calibration for the MPR spectrometer was performed by using the HI-13 tandem accelerator at China Institute of Atomic Energy (CIAE), and the NDE calibration was performed by using the neutron generator at CIAE. The specific calibration techniques used in this work and the associated accuracies were discussed in details in this paper. The calibration results were presented along with Monte Carlo simulation results.

  14. Spectroscopy of {sup 144}Ho using recoil-isomer tagging

    SciTech Connect

    Mason, P. J. R; Cullen, D. M.; Scholey, C.; Greenlees, P. T.; Jakobsson, U.; Jones, P. M.; Julin, R.; Juutinen, S.; Ketelhut, S.; Leino, M.; Nyman, M.; Peura, P.; Puurunen, A.; Rahkila, P.; Ruotsalainen, P.; Sorri, J.; Saren, J.; Uusitalo, J.; Xu, F. R.

    2010-02-15

    Excited states in the proton-unbound odd-odd nucleus {sup 144}Ho have been populated using the {sup 92}Mo({sup 54}Fe,pn){sup 144}Ho reaction and studied using the recoil-isomer-tagging technique. The alignment properties and signature splitting of the rotational band above the I{sup p}i=(8{sup +}){sup 144m}Ho isomer have been analyzed and the isomer confirmed to have a pih{sub 11/2} x nuh{sub 11/2} two-quasiparticle configuration. The configuration-constrained blocking method has been used to calculate the shapes of the ground and isomeric states, which are both predicted to have triaxial nuclear shapes with |gamma|approx =24 deg.

  15. A Study of Nuclear Recoils in Liquid Argon Time Projection Chamber for the Direct Detection of WIMP Dark Matter

    SciTech Connect

    Cao, Huajie

    2014-11-01

    Robust results of WIMP direct detection experiments depend on rm understandings of nuclear recoils in the detector media. This thesis documents the most comprehensive study to date on nuclear recoils in liquid argon - a strong candidate for the next generation multi-ton scale WIMP detectors. This study investigates both the energy partition from nuclear recoil energy to secondary modes (scintillation and ionization) and the pulse shape characteristics of scintillation from nuclear recoils.

  16. Alpha-recoil thorium-234: dissolution into water and the uranium-234/uranium-238 disequilibrium in nature.

    PubMed

    Kigoshi, K

    1971-07-01

    The rate of ejection of alpha-recoil thorium-234 into solution from the surface of zircon sand gives an alpha-recoil range of 550 angstroms. The alpha-recoil thorium-234 atoms ejected into the groundwater may supply excess uranium-234. In pelagic sediments, ejected alpha-recoil thorium-234 may contribute to the supply of mobile uranium-234 in the sedimentary column. PMID:17747313

  17. The Yale Gas-Filled Split Pole Magnetic Separator

    NASA Astrophysics Data System (ADS)

    Cata-Danil, G.; Beausang, C. W.; Casten, R. F.; Chen, A.; Chubrich, N.; Cooper, J. R.; Krücken, R.; Liu, B.; Novak, J. R.; Visser, D.; Zamfir, N. V.

    1998-10-01

    Design and construction of a gas-filled recoil separator is underway at the Wright Nuclear Structure Laboratory at Yale University. By filling the magnetic field region of the existing Enge Split-Pole magnet with N2 or He2 gases in the 1 to 15 mbar pressure range a gradual focussing of discrete charge states has been measured. The incident ions were ^16O and ^35,37Cl with 49 MeV and 95 MeV energies, respectively. The process is understood as a result of coalescing of trajectories of different charge states around a trajectory defined by the mean charge state (q¯) of the ion in gas. Because q¯ depends on the atomic number Z and is roughly proportional with the ion velocity, the average magnetic rigidity (B¯ρ=Av/q¯) is almost independent of the velocity distribution of the incident ions. The ion trajectories will be therefore be mainly determined by the mass number A and the atomic number Z of the ion. Monte Carlo simulations with the code RAYTRACE closely reproduce the experimental behavior. We plan to use the Yale Mass Separator (YaMS) for nuclear structure studies in conjunction with high efficency gamma detectors (clover detectors) for enhancing weak reaction channels and fission background reduction. Work supported by the US-DOE under contract numbers DE-FG02-91ER-40609 and DE-FG02-88ER-40417.

  18. Extra-large remnant recoil velocities and spins from near-extremal-Bowen-York-spin black-hole binaries

    SciTech Connect

    Dain, Sergio; Lousto, Carlos O.; Zlochower, Yosef

    2008-07-15

    We evolve equal-mass, equal-spin black-hole binaries with specific spins of a/m{sub H}{approx}0.925, the highest spins simulated thus far and nearly the largest possible for Bowen-York black holes, in a set of configurations with the spins counteraligned and pointing in the orbital plane, which maximizes the recoil velocities of the merger remnant, as well as a configuration where the two spins point in the same direction as the orbital angular momentum, which maximizes the orbital hangup effect and remnant spin. The coordinate radii of the individual apparent horizons in these cases are very small and the simulations require very high central resolutions (h{approx}M/320). We find that these highly spinning holes reach a maximum recoil velocity of {approx}3300 km s{sup -1} (the largest simulated so far) and, for the hangup configuration, a remnant spin of a/m{sub H}{approx}0.922. These results are consistent with our previous predictions for the maximum recoil velocity of {approx}4000 km s{sup -1} and remnant spin; the latter reinforcing the prediction that cosmic censorship is not violated by merging highly spinning black-hole binaries. We also numerically solve the initial data for, and evolve, a single maximal-Bowen-York-spin black hole, and confirm that the 3-metric has an O(r{sup -2}) singularity at the puncture, rather than the usual O(r{sup -4}) singularity seen for nonmaximal spins.

  19. A THERMAL INFRARED IMAGING STUDY OF VERY LOW MASS, WIDE-SEPARATION BROWN DWARF COMPANIONS TO UPPER SCORPIUS STARS: CONSTRAINING CIRCUMSTELLAR ENVIRONMENTS

    SciTech Connect

    Bailey, Vanessa; Hinz, Philip M.; Su, Kate Y. L.; Hoffmann, William F.; Rieke, George; Rodigas, Timothy; Skemer, Andrew; Vaitheeswaran, Vidhya; Currie, Thayne; Esposito, Simone; Pinna, Enrico; Puglisi, Alfio; Hill, John M.; Jones, Terry; Kim, Jihun; Leisenring, Jarron; Meyer, Michael; Murray-Clay, Ruth; Skrutskie, Michael F.; Nelson, Matthew J.; and others

    2013-04-10

    We present a 3-5 {mu}m LBT/MMT adaptive optics imaging study of three Upper Scorpius stars with brown dwarf (BD) companions with very low masses/mass ratios (M{sub BD} <25 M{sub Jup}; M{sub BD}/M{sub *} Almost-Equal-To 1%-2%) and wide separations (300-700 AU): GSC 06214, 1RXS 1609, and HIP 78530. We combine these new thermal IR data with existing 1-4 {mu}m and 24 {mu}m photometry to constrain the properties of the BDs and identify evidence for circumprimary/circumsecondary disks in these unusual systems. We confirm that GSC 06214B is surrounded by a disk, further showing that this disk produces a broadband IR excess due to small dust near the dust sublimation radius. An unresolved 24 {mu}m excess in the system may be explained by the contribution from this disk. 1RXS 1609B exhibits no 3-4 {mu}m excess, nor does its primary; however, the system as a whole has a modest 24 {mu}m excess, which may come from warm dust around the primary and/or BD. Neither object in the HIP 78530 system exhibits near- to mid-IR excesses. We additionally find that the 1-4 {mu}m colors of HIP 78530B match a spectral type of M3 {+-} 2, inconsistent with the M8 spectral type assigned based on its near-IR spectrum, indicating that it may be a low-mass star rather than a BD. We present new upper limits on additional low-mass companions in the system (<5 M{sub Jup} beyond 175 AU). Finally, we examine the utility of circumsecondary disks as probes of the formation histories of wide BD companions, finding that the presence of a disk may disfavor BD formation near the primary with subsequent outward scattering.

  20. Separating refractory and non-refractory particulate chloride and estimating chloride depletion by aerosol mass spectrometry in a marine environment

    NASA Astrophysics Data System (ADS)

    Nuaaman, I.; Li, S.-M.; Hayden, K. L.; Onasch, T. B.; Massoli, P.; Sueper, D.; Worsnop, D. R.; Bates, T. S.; Quinn, P. K.; McLaren, R.

    2015-01-01

    Aerosol composition and concentration measurements along the coast of California were obtained using an Aerodyne high-resolution time-of-flight aerosol mass spectrometer (HR-AMS) onboard the research vessel Atlantis during the CalNex study in 2010. This paper focuses on the measurement of aerosol chloride using the HR-AMS that can be ambiguous in regions with significant quantities of sea salt aerosols. This ambiguity arises due to large differences in the sensitivity of the HR-AMS to refractory chloride species (i.e., NaCl) and non refractory chloride species (i.e., NH4Cl, HCl, etc.). Using the HR-AMS, the aerosol chloride signal is typically quantified using ion signals for 35Cl+, H35Cl+, 37Cl+ and H37Cl+ (HxCl+). During this study, the highest aerosol chloride signal was observed during sea sweep experiments when the source of the aerosol chloride was NaCl present in artificially generated sea salt aerosols even though the HR-AMS has significantly lower sensitivity to such refractory species. Other prominent ion signals that arise from NaCl salt were also observed at m/z 22.99 for Na+ and m/z 57.96 for Na35Cl+ during both sea sweep experiments and during periods of ambient measurements. Thus, refractory NaCl contributes significantly to the HxCl+ signal, interfering with attempts to quantify non sea salt chloride (nssCl). It was found that during ambient aerosol measurements, the interference in the HxCl+ signal from sea salt chloride (ssCl) was as high as 89%, but with a study wide average of 10%. The Na35Cl+ ion signal was found to be a good tracer for NaCl. We outline a method to establish nssCl in the ambient aerosols by subtracting the sea salt chloride (ssCl) signal from the HxCl+ signal. The ssCl signal is derived from the Na35Cl+ ion tracer signal and the HxCl+ to Na35Cl+ ratio established from the sea sweep experiments. Ambient submicron concentrations of ssCl were also established using the Na35Cl

  1. Detection and quantification of some plant growth regulators in a seaweed-based foliar spray employing a mass spectrometric technique sans chromatographic separation.

    PubMed

    Prasad, Kamalesh; Das, Arun Kumar; Oza, Mihir Deepak; Brahmbhatt, Harshad; Siddhanta, Arup Kumar; Meena, Ramavatar; Eswaran, Karuppanan; Rajyaguru, Mahesh Rameshchandra; Ghosh, Pushpito Kumar

    2010-04-28

    The sap expelled from the fresh harvest of Kappaphycus alvarezii , a red seaweed growing in tropical waters, has been reported to be a potent foliar spray. Tandem mass spectrometry of various organic extracts of the sap confirmed the presence of the plant growth regulators (PGRs) indole 3-acetic acid, gibberellin GA(3), kinetin, and zeatin. These PGRs were quantified in fresh state and after 1 year of storage by ESI-MS without recourse to chromatographic separation. Quantification was validated against HPLC data. The results may be useful in correlating with the efficacy of the sap. The methodology was extended to two other seaweeds. The method developed is convenient and precise and may find application in other agricultural formulations containing these growth hormones. PMID:20355716

  2. Two-dimensional separation of the membrane protein sarcoplasmic reticulum Ca-ATPase for high-performance liquid chromatography-tandem mass spectrometry analysis of posttranslational protein modifications.

    PubMed

    Sharov, Victor S; Galeva, Nadezhda A; Knyushko, Tatyana V; Bigelow, Diana J; Williams, Todd D; Schöneich, Christian

    2002-09-15

    For the characterization of posttranslational modifications of the sarcoplasmic/endoplasmic reticulum Ca-ATPase (SERCA), we developed a two-dimensional separation protocol based on reversed-phase HPLC followed by SDS-PAGE and LC-MS/MS analysis of in-gel tryptic digests. Representative experiments are shown for the rabbit fast-twitch skeletal muscle isoform SERCA1. Matrix-assisted laser desorption-ionization and electrospray ionization-mass spectrometry analyses of SERCA1 tryptic digests revealed ca. 66% coverage of the protein sequence. This approach was used for the detection and quantitation of nitrotyrosine formation after exposure of SERCA1 to peroxynitrite in vitro. At molar ratios of nitrotyrosine to protein of 0.23 we confirmed by LC-MS/MS the nitration of predominantly Tyr(122) in the SERCA1 sequence. PMID:12419347

  3. Development of an LC-tandem mass spectrometry method for the separation of montelukast and its application to a pharmacokinetic study in humans.

    PubMed

    Ezzeldin, E; Tammam, M H; AboTalib, N F

    2014-11-01

    Accurate, precise, and sensitive LC-MS/MS assay method for the determination of montelukast (MO) in human plasma samples using gliclazide (GL) as internal standard was developed and applied in pharmacokinetics study.MO extracted by protein precipitation using acetonitrile. Chromatographic separation was carried out using a Agilant Triple quadrupoles mass spectrometer with API source with an Agilant SB- C18 (50×4.6 mm), 1.8 µm particle size column. A mobile phase consisting of acetonitrile: 0.1% formic acid (84:16) was delivered. Calibration curves were linear in the concentration range of (10.00-800.00) ng/ml. The bioanalytical method for determination of MO was successfully applied to assess pharmacokinetics of montelukast. The LLOQ was sensitive enough for detecting terminal phase concentrations of the drug. This study showed that developed method is suitable for MO pharmacokinetic study. PMID:24500731

  4. Separation of silver ions and starch modified silver nanoparticles using high performance liquid chromatography with ultraviolet and inductively coupled mass spectrometric detection

    NASA Astrophysics Data System (ADS)

    Hanley, Traci A.; Saadawi, Ryan; Zhang, Peng; Caruso, Joseph A.; Landero-Figueroa, Julio

    2014-10-01

    The production of commercially available products marketed to contain silver nanoparticles is rapidly increasing. Species-specific toxicity is a phenomenon associated with many elements, including silver, making it imperative to develop a method to identify and quantify the various forms of silver (namely, silver ions vs. silver nanoparticles) possibly present in these products. In this study a method was developed using high performance liquid chromatography (HPLC) with ultraviolet (UV-VIS) and inductively coupled mass spectrometric (ICP-MS) detection to separate starch stabilized silver nanoparticles (AgNPs) and silver ions (Ag+) by cation exchange chromatography with 0.5 M nitric acid mobile phase. The silver nanoparticles and ions were baseline resolved with an ICP-MS response linear over four orders of magnitude, 0.04 mg kg- 1 detection limit, and 90% chromatographic recovery for silver solutions containing ions and starch stabilized silver nanoparticles smaller than 100 nm.

  5. Enhanced capabilities for imaging gangliosides in murine brain with matrix-assisted laser desorption/ionization and desorption electrospray ionization mass spectrometry coupled to ion mobility separation.

    PubMed

    Škrášková, Karolina; Claude, Emmanuelle; Jones, Emrys A; Towers, Mark; Ellis, Shane R; Heeren, Ron M A

    2016-07-15

    The increased interest in lipidomics calls for improved yet simplified methods of lipid analysis. Over the past two decades, mass spectrometry imaging (MSI) has been established as a powerful technique for the analysis of molecular distribution of a variety of compounds across tissue surfaces. Matrix-assisted laser desorption/ionization (MALDI) MSI is widely used to study the spatial distribution of common lipids. However, a thorough sample preparation and necessity of vacuum for efficient ionization might hamper its use for high-throughput lipid analysis. Desorption electrospray ionization (DESI) is a relatively young MS technique. In DESI, ionization of molecules occurs under ambient conditions, which alleviates sample preparation. Moreover, DESI does not require the application of an external matrix, making the detection of low mass species more feasible due to the lack of chemical matrix background. However, irrespective of the ionization method, the final information obtained during an MSI experiment is very complex and its analysis becomes challenging. It was shown that coupling MSI to ion mobility separation (IMS) simplifies imaging data interpretation. Here we employed DESI and MALDI MSI for a lipidomic analysis of the murine brain using the same IMS-enabled instrument. We report for the first time on the DESI IMS-MSI of multiply sialylated ganglioside species, as well as their acetylated versions, which we detected directly from the murine brain tissue. We show that poly-sialylated gangliosides can be imaged as multiply charged ions using DESI, while they are clearly separated from the rest of the lipid classes based on their charge state using ion mobility. This represents a major improvement in MSI of intact fragile lipid species. We additionally show that complementary lipid information is reached under particular conditions when DESI is compared to MALDI MSI. PMID:26922843

  6. Polar Aprotic Modifiers for Chromatographic Separation and Back-Exchange Reduction for Protein Hydrogen/Deuterium Exchange Monitored by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

    NASA Astrophysics Data System (ADS)

    Valeja, Santosh G.; Emmett, Mark R.; Marshall, Alan G.

    2012-04-01

    Hydrogen/deuterium exchange monitored by mass spectrometry is an important non-perturbing tool to study protein structure and protein-protein interactions. However, water in the reversed-phase liquid chromatography mobile phase leads to back-exchange of D for H during chromatographic separation of proteolytic peptides following H/D exchange, resulting in incorrect identification of fast-exchanging hydrogens as unexchanged hydrogens. Previously, fast high-performance liquid chromatography (HPLC) and supercritical fluid chromatography have been shown to decrease back-exchange. Here, we show that replacement of up to 40% of the water in the LC mobile phase by the modifiers, dimethylformamide (DMF) and N-methylpyrrolidone (NMP) (i.e., polar organic modifiers that lack rapid exchanging hydrogens), significantly reduces back-exchange. On-line LC micro-ESI FT-ICR MS resolves overlapped proteolytic peptide isotopic distributions, allowing for quantitative determination of the extent of back-exchange. The DMF modified solvent composition also improves chromatographic separation while reducing back-exchange relative to conventional solvent.

  7. A novel phosphoprotein analysis scheme for assessing changes in premalignant and malignant breast cell lines using 2D liquid separations, protein microarrays and tandem mass spectrometry

    PubMed Central

    Patwa, Tasneem H.; Wang, Yanfei; Miller, Fred R.; Goodison, Steve; Pennathur, Subramaniam; Barder, Timothy J.; Lubman, David M.

    2008-01-01

    An analysis of phosphorylation changes that occur during cancer progression would provide insights into the molecular pathways responsible for a malignant phenotype. In this study we employed a novel coupling of 2D-liquid separations and protein microarray technology to reveal changes in phosphoprotein status between premalignant (AT1) and malignant (CA1a) cell lines derived from the human MCF10A breast cell lines. Intact proteins were first separated according to their isoelectric point and hydrophobicities, then arrayed on SuperAmine glass slides. Phosphoproteins were detected using the universal, inorganic phospho-sensor dye, ProQ Diamond. Using this dye, out of 140 spots that were positive for phosphorylation, a total of 85 differentially expressed spots were detected over a pH range of 7.2 to 4.0. Proteins were identified and their peptides sequenced by mass spectrometry. The strategy enabled the identification of 75 differentially expressed phosphoproteins, from which 51 phosphorylation sites in 27 unique proteins were confirmed. Interestingly, the majority of differentially expressed phosphorylated proteins observed were nuclear proteins. Three regulators of apoptosis, Bad, Bax and Acinus, were also differentially phosphorylated in the two cell lines. Further development of this strategy will facilitate an understanding of the mechanisms involved in malignancy progression and other disease-related phenotypes. PMID:19194518

  8. On-target separation of analyte with 3-aminoquinoline/α-cyano-4-hydroxycinnamic acid liquid matrix for matrix-assisted laser desorption/ionization mass spectrometry.

    PubMed

    Sekiya, Sadanori; Taniguchi, Kenichi; Tanaka, Koichi

    2012-03-30

    3-Aminoquinoline/α-cyano-4-hydroxycinnamic acid (3AQ/CHCA) is a liquid matrix (LM), which was reported by Kumar et al. in 1996 for matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. It is a viscous liquid and has some advantages of durability of ion generation by a self-healing surface and quantitative performance. In this study, we found a novel aspect of 3AQ/CHCA as a MALDI matrix, which converges hydrophilic material into the center of the droplet of analyte-3AQ/CHCA mixture on a MALDI sample target well during the process of evaporation of water derived from analyte solvent. This feature made it possible to separate not only the buffer components, but also the peptides and oligosaccharides from one another within 3AQ/CHCA. The MALDI imaging analyses of the analyte-3AQ/CHCA droplet indicated that the oligosaccharides and the peptides were distributed in the center and in the whole area around the center of 3AQ/CHCA, respectively. This 'on-target separation' effect was also applicable to glycoprotein digests such as ribonuclease B. These features of 3AQ/CHCA liquid matrix eliminate the requirement for pretreatment, and reduce sample handling losses thus resulting in the improvement of throughput and sensitivity. PMID:22328224

  9. Simultaneous separation and determination of six arsenic species in rice by anion-exchange chromatography with inductively coupled plasma mass spectrometry.

    PubMed

    Ma, Li; Yang, Zhaoguang; Tang, Jie; Wang, Lin

    2016-06-01

    The simultaneous separation and determination of arsenite As(III), arsenate As(V), monomethylarsonic acid (MMA), dimethylarsinic acid (DMA), arsenobetaine (AsB), and arsenocholine (AsC) in rice samples have been carried out in one single anion-exchange column run by high-performance liquid chromatography with inductively coupled plasma mass spectrometry. To estimate the effect of variables on arsenic (As) speciation, the chromatographic conditions including type of competing anion, ionic strength, pH of elution buffer, and flow rate of mobile phase have been investigated by a univariate approach. Under the optimum chromatographic conditions, baseline separation of six As species has been achieved within 10 min by gradient elution program using 4 mM NH4 HCO3 at pH 8.6 as mobile phase A and 4 mM NH4 HCO3 , 40 mM NH4 NO3 at pH 8.6 as mobile phase B. The method detection limits for As(III), As(V), MMA, DMA, AsB, and AsC were 0.4, 0.9, 0.2, 0.4, 0.5, and 0.3 μg/kg, respectively. The proposed method has been applied to separation and quantification of As species in real rice samples collected from Hunan Province, China. The main As species detected in all samples were As(III), As(V) and DMA, with inorganic As accounting for over 80% of total As in these samples. PMID:27062347

  10. Determination of methylmercury and inorganic mercury by coupling short-column ion chromatographic separation, on-line photocatalyst-assisted vapor generation, and inductively coupled plasma mass spectrometry.

    PubMed

    Chen, Kuan-ju; Hsu, I-hsiang; Sun, Yuh-chang

    2009-12-18

    We have combined short-column ion chromatographic separation and on-line photocatalyst-assisted vapor generation (VG) techniques with inductively coupled plasma mass spectrometry to develop a simple and sensitive hyphenated method for the determination of aqueous Hg(2+) and MeHg(+) species. The separation of Hg(2+) and MeHg(+) was accomplished on a cation-exchange guard column using a glutathione (GSH)-containing eluent. To achieve optimal chromatographic separation and signal intensities, we investigated the influence of several of the operating parameters of the chromatographic and photocatalyst-assisted VG systems. Under the optimized conditions of VG process, the shortcomings of conventional SnCl(2)-based VG techniques for the vaporization of MeHg(+) was overcome; comparing to the concentric nebulizer-ICP-MS system, the analytical sensitivity of ICP-MS toward the detection of Hg(2+) and MeHg(+) were also improved to 25- and 7-fold, respectively. With the use of our established HPLC-UV/nano-TiO(2)-ICP-MS system, the precision for each analyte, based on three replicate injections of 2 ng/mL samples of each species, was better than 15% RSD. This hyphenated method also provided excellent detection limits--0.1 and 0.03 ng/mL for Hg(2+) and MeHg(+), respectively. A series of validation experiments--analysis of the NIST 2672a Standard Urine Reference Material and other urine samples--confirmed further that our proposed method could be applied satisfactorily to the determination of inorganic Hg(2+) and MeHg(+) species in real samples. PMID:19913233

  11. Damped elastic recoil of the titin spring in myofibrils of human myocardium

    PubMed Central

    Opitz, Christiane A.; Kulke, Michael; Leake, Mark C.; Neagoe, Ciprian; Hinssen, Horst; Hajjar, Roger J.; Linke, Wolfgang A.

    2003-01-01

    The giant protein titin functions as a molecular spring in muscle and is responsible for most of the passive tension of myocardium. Because the titin spring is extended during diastolic stretch, it will recoil elastically during systole and potentially may influence the overall shortening behavior of cardiac muscle. Here, titin elastic recoil was quantified in single human heart myofibrils by using a high-speed charge-coupled device-line camera and a nanonewtonrange force sensor. Application of a slack-test protocol revealed that the passive shortening velocity (Vp) of nonactivated cardiomyofibrils depends on: (i) initial sarcomere length, (ii) release-step amplitude, and (iii) temperature. Selective digestion of titin, with low doses of trypsin, decelerated myofibrillar passive recoil and eventually stopped it. Selective extraction of actin filaments with a Ca2+-independent gelsolin fragment greatly reduced the dependency of Vp on release-step size and temperature. These results are explained by the presence of viscous forces opposing myofibrillar passive recoil that are caused mainly by weak actin–titin interactions. Thus, Vp is determined by two distinct factors: titin elastic recoil and internal viscous drag forces. The recoil could be modeled as that of a damped entropic spring consisting of independent worm-like chains. The functional importance of myofibrillar elastic recoil was addressed by comparing instantaneous Vp to unloaded shortening velocity, which was measured in demembranated, fully Ca2+-activated, human cardiac fibers. Titin-driven passive recoil was much faster than active unloaded shortening velocity in early phases of isotonic contraction. Damped myofibrillar elastic recoil could help accelerate active contraction speed of human myocardium during early systolic shortening. PMID:14563922

  12. Detection of bacteria from biological mixtures using immunomagnetic separation combined with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

    USGS Publications Warehouse

    Madonna, A.J.; Basile, F.; Furlong, E.; Voorhees, K.J.

    2001-01-01

    A rapid method for identifying specific bacteria from complex biological mixtures using immunomagnetic separation coupled to matrix-assisted laser desorption/ionization time-of-flight mass spectrometry has been developed. The technique employs commercially available magnetic beads coated with polycolonal antibodies raised against specific bacteria and whole cell analysis by MALDI-MS. A suspension of a bacterial mixture is mixed with the immunomagnetic beads specific for the target microorganism. After a short incubation period (20 mins) the bacteria captured by the beads are washed, resuspended in deionized H2O and directly applied onto a MALDI probe. Liquid suspensions containing bacterial mixtures can be screened within 1 h total analysis time. Positive tests result in the production of a fingerprint mass spectrum primarily consisting of protein biomarkers characteristic of the targeted microorganism. Using this procedure, Salmonella choleraesuis was isolated and detected from standard bacterial mixtures and spiked samples of river water, human urine, and chicken blood. Copyright ?? 2001 John Wiley & Sons, Ltd.

  13. Chromatographic enrichment and subsequent separation of nickel and vanadyl porphyrins from natural seeps and molecular characterization by positive electrospray ionization FT-ICR mass spectrometry.

    PubMed

    Putman, Jonathan C; Rowland, Steven M; Corilo, Yuri E; McKenna, Amy M

    2014-11-01

    We report a novel chromatographic method to enrich and separate nickel and vanadyl porphyrins from a natural seep sample and combine molecular level characterization by positive-ion electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). Vanadyl and nickel porphyrin model compound elution from primary secondary amine (PSA) stationary phase combined with UV-vis spectroscopy confirms enrichment and subsequent fractionation of nickel and vanadyl porphyrins into polarity-based subfractions. A more than 100-fold increase in signal-to-noise ratio for nickel porphyrins enables unequivocal elemental composition assignment confirmed by isotopic fine structure for all isotopes >1% relative abundance, and the first mass spectral identification of (61)Ni porphyrin isotopologues derived from natural seeps. Oxygen-containing vanadyl porphyrins and sulfur-containing vanadyl porphyrins are isolated in the same fraction simultaneously from the same sample. We provide the first chromatographic evidence of carboxylic acid functionalities peripheral to the porphyrin core, in agreement with previous studies. PMID:25286139

  14. Determination of trace phosphorus in high purity tantalum materials by inductively coupled plasma mass spectrometry subsequent to matrix separation with on-line anion exchange/coprecipitation.

    PubMed

    Kozono, Shuji; Takahashi, Shigeto; Haraguchi, Hiroki

    2002-02-01

    An on-line matrix separation/inductively coupled plasma mass spectrometry (ICP-MS) method is proposed for the determination of trace amounts of phosphorus in high purity tantalum metal, tantalum (V) oxide, and tantalum pentaethoxide. In the present method, the matrix tantalum in the sample solution was adsorbed on the anion exchange resin, and phosphorus (phosphate ion) was eluted with the carrier solution of HF and HNO3 mixture. Then, the effluent solution was subsequently mixed with bismuth solution and aqueous ammonia solution to coprecipitate phosphate together with bismuth hydroxide. The precipitate formed was collected on the in-line membrane filter to wash out nitric acid with pure water, and then dissolved with hydrochloric acid. The obtained phosphorus sample solution was introduced directly into the nebulizer of ICP-MS for the determination of phosphorus. Phosphorus was determined at the molecular ion signal of 31P16O+ (m/z 47). The detection limit (3sigma) of phosphorus in the present method was 1.3 ng mL(-1) as the sample solution basis, and the relative standard deviation for 30 ng mL(-1) of phosphorus in the standard solution was 4.3% in the replicate measurements (n=11). The present method was applied to the analysis of high purity tantalum materials. The concentrations of phosphorus in tantalum samples were in fairly good agreement with those obtained by glow discharge mass spectrometry (GDMS). PMID:11939629

  15. High-energy recoil-ion emission in keV heavy-ion surface collisions

    NASA Astrophysics Data System (ADS)

    van Someren, B.; Rudolph, H.; Urazgil'din, I. F.; van Emmichoven, P. A. Zeijlmans; Niehaus, A.

    1997-11-01

    For keV Xe +, Kr + and Ar + ions incident at 30° on Cu(110) we have observed the emission of negatively charged particles with energies up to about 40% of the primary energy. By time-of-flight techniques we have found that electrons are emitted with energies up to 80 eV, whereas the negatively charged high-energy particles are Cu - recoil ions. High-energy Cu + ions have also been found. Simple energy and momentum conservation arguments show that such high recoil energies are indeed possible for multiple collision events in which the primary recoil ion scatters off one or more Cu atoms.

  16. Nuclear recoil energy scale in liquid xenon with application to the direct detection of dark matter

    SciTech Connect

    Sorensen, P; Dahl, C E

    2011-02-14

    We show for the first time that the quenching of electronic excitation from nuclear recoils in liquid xenon is well-described by Lindhard theory, if the nuclear recoil energy is reconstructed using the combined (scintillation and ionization) energy scale proposed by Shutt et al.. We argue for the adoption of this perspective in favor of the existing preference for reconstructing nuclear recoil energy solely from primary scintillation. We show that signal partitioning into scintillation and ionization is well-described by the Thomas-Imel box model. We discuss the implications for liquid xenon detectors aimed at the direct detection of dark matter.

  17. The quasielastic 2H(e,e'p)n reaction at high recoil momenta

    SciTech Connect

    D. Crovelli; Konrad Aniol; Javier Gomez; John LeRose; Arunava Saha; Paul Ulmer; Vina Punjabi; Richard Lindgren; Charles Perdrisat; David Meekins; Joseph Mitchell; Mark Jones; Robert Michaels; Bogdan Wojtsekhowski; Hartmuth Arenhoevel; Michael Finn; Jens-Ole Hansen; Riad Suleiman; Kevin Fissum; Sergey Malov; Cornelis De Jager; Cornelis de Jager; Rikki Roche; Michael Kuss; Eugene Chudakov; Sabine Jeschonnek; Franck Sabatie; Luminita Todor; Meihua Liang; Olivier Gayou; Jian-Ping Chen

    2001-11-01

    The 2H(e,e'p)n cross section was measured in Hall A of the Thomas Jefferson National Accelerator Facility (JLab) in quasielastic kinematics (x=0.96) at a four-momentum transfer squared, Q{sup 2}=0.67 (GeV/c){sup 2}. The experiment was performed in fixed electron kinematics for recoil momenta from zero to 550 MeV/c. Though the measured cross section deviates by 1-2 sigma from a state-of-the-art calculation at low recoil momenta, it agrees at high recoil momenta where final state interactions (FSI) are predicted to be large.

  18. Recoil-nucleus spectra in the interaction of cosmic-ray protons with spacecraft electronics

    SciTech Connect

    Chuvilskaya, T. V.; Shirokova, A. A.; Kadmenskii, A. G.; Chechenin, N. G.

    2008-07-15

    The cross sections for nuclear reactions induced by 50-to 1000-MeV protons in silicon and the angular distributions of products of these reactions are calculated, along with the recoil-nucleus spectra. The recoil-nucleus spectra are shown to contain a monotonically decreasing portion and a recoil peak, which is manifested most clearly at incident-proton energies in excess of 100 MeV. The possibility of employing these results to derive more reliable estimates of single-event upsets in onboard spacecraft electronics is discussed.

  19. Retention studies of recoiling daughter nuclides of 225Ac in polymer vesicles.

    PubMed

    Wang, G; de Kruijff, R M; Rol, A; Thijssen, L; Mendes, E; Morgenstern, A; Bruchertseifer, F; Stuart, M C A; Wolterbeek, H T; Denkova, A G

    2014-02-01

    Alpha radionuclide therapy is steadily gaining importance and a large number of pre-clinical and clinical studies have been carried out. However, due to the recoil effects the daughter recoil atoms, most of which are alpha emitters as well, receive energies that are much higher than the energies of chemical bonds resulting in decoupling of the radionuclide from common targeting agents. Here, we demonstrate that polymer vesicles (i.e. polymersomes) can retain recoiling daughter nuclei based on an experimental study examining the retention of (221)Fr and (213)Bi when encapsulating (225)Ac. PMID:24374072

  20. A study of intrinsic statistical variation for low-energy nuclear recoils in liquid xenon detector for dark matter searches

    NASA Astrophysics Data System (ADS)

    Wang, Lu; Wei, Wenzhao; Mei, Dongming; Cubed Collaboration

    2015-10-01

    Noble liquid xenon experiments, such as XENON100, LUX, XENON 1-Ton, and LZ are large dark matter experiments directly searches for weakly interacting massive particles (WIMPs). One of the most important features is to discriminate nuclear recoils from electronic recoils. Detector response is generally calibrated with different radioactive sources including 83mKr, tritiated methane, 241AmBe, 252Cf, and DD-neutrons. The electronic recoil and nuclear recoil bands have been determined by these calibrations. However, the width of nuclear recoil band needs to be fully understood. We derive a theoretical model to understand the correlation of the width of nuclear recoil band and intrinsic statistical variation. In addition, we conduct experiments to validate the theoretical model. In this paper, we present the study of intrinsic statistical variation contributing to the width of nuclear recoil band. DE-FG02-10ER46709 and the state of South Dakota.

  1. A Thermal Infrared Imaging Study of Very Low Mass, Wide-separation Brown Dwarf Companions to Upper Scorpius Stars: Constraining Circumstellar Environments

    NASA Astrophysics Data System (ADS)

    Bailey, Vanessa; Hinz, Philip M.; Currie, Thayne; Su, Kate Y. L.; Esposito, Simone; Hill, John M.; Hoffmann, William F.; Jones, Terry; Kim, Jihun; Leisenring, Jarron; Meyer, Michael; Murray-Clay, Ruth; Nelson, Matthew J.; Pinna, Enrico; Puglisi, Alfio; Rieke, George; Rodigas, Timothy; Skemer, Andrew; Skrutskie, Michael F.; Vaitheeswaran, Vidhya; Wilson, John C.

    2013-04-01

    We present a 3-5 μm LBT/MMT adaptive optics imaging study of three Upper Scorpius stars with brown dwarf (BD) companions with very low masses/mass ratios (M BD <25 M Jup; M BD/M sstarf ≈ 1%-2%) and wide separations (300-700 AU): GSC 06214, 1RXS 1609, and HIP 78530. We combine these new thermal IR data with existing 1-4 μm and 24 μm photometry to constrain the properties of the BDs and identify evidence for circumprimary/circumsecondary disks in these unusual systems. We confirm that GSC 06214B is surrounded by a disk, further showing that this disk produces a broadband IR excess due to small dust near the dust sublimation radius. An unresolved 24 μm excess in the system may be explained by the contribution from this disk. 1RXS 1609B exhibits no 3-4 μm excess, nor does its primary; however, the system as a whole has a modest 24 μm excess, which may come from warm dust around the primary and/or BD. Neither object in the HIP 78530 system exhibits near- to mid-IR excesses. We additionally find that the 1-4 μm colors of HIP 78530B match a spectral type of M3 ± 2, inconsistent with the M8 spectral type assigned based on its near-IR spectrum, indicating that it may be a low-mass star rather than a BD. We present new upper limits on additional low-mass companions in the system (<5 M Jup beyond 175 AU). Finally, we examine the utility of circumsecondary disks as probes of the formation histories of wide BD companions, finding that the presence of a disk may disfavor BD formation near the primary with subsequent outward scattering. Observations reported here were obtained at the LBT and MMT Observatories. The MMT Observatory is a joint facility of the University of Arizona and the Smithsonian Institution. The LBT is an international collaboration among institutions in the United States, Italy, and Germany. LBT Corporation partners are: The University of Arizona on behalf of the Arizona university system; Istituto Nazionale di Astrofisica, Italy; LBT

  2. Elastic recoil of coronary stents: a comparative analysis.

    PubMed

    Barragan, P; Rieu, R; Garitey, V; Roquebert, P O; Sainsous, J; Silvestri, M; Bayet, G

    2000-05-01

    Minimum elastic recoil (ER) has became an essential feature of new coronary stents when deployed in artheromatous lesions of various morphologies. The ER of coronary stent might be an important component of 6-month restenosis rate by minimizing the luminal loss. We evaluated the intrinsic ER of 23 coronary stents with a mechanical test bench. The amount of ER for one size of stent (3.0 mm) was quantified using a 3D optical contactless machine (Smartscope MVP, Rochester, NY). The stents were expanded on their own balloon for the precrimped stents; the uncrimped stents were expended using identical 3.0-mm balloons. Two types of measurements were done without exterior stress and with a 0.2-bar exterior stress, directly on the stent at the end of balloon expansion, immediately after balloon deflation, and then 30 min, 60 min, and 120 min after. ER ranged from 1.54%+/-0.81% (Bestent BES 15) to 16.51%+/-2.89% (Paragon stent) without stress (P<0.01) and from 2.35%+/-1.14% (Bestent BES 15) to 18.34%+/-2.41% (Cook GR2) under 0.2-bar pressure (P<0.0001). Furthermore, there was a significant reduction between the mean result of tubular stents (TS) and coil stents (CS). The results of in vitro mechanical tests may confirm strongly the interest of a minimum ER in the prevention of the 6-month restenosis. PMID:10816295

  3. Fast thermometry for trapped atoms using recoil-induced resonance

    NASA Astrophysics Data System (ADS)

    Zhao, Yan-Ting; Su, Dian-Qiang; Ji, Zhong-Hua; Zhang, Hong-Shan; Xiao, Lian-Tuan; Jia, Suo-Tang

    2015-09-01

    We have employed recoil-induced resonance (RIR) with linewidth on the order of 10 kHz to demonstrate the fast thermometry for ultracold atoms. We theoretically calculate the absorption spectrum of RIR which agrees well with the experimental results. The temperature of the ultracold sample derived from the RIR spectrum is T = 84±4.5 μK, which is close to 85 μK that measured by the method of time-of-flight absorption imaging. To exhibit the fast measurement advantage in applying RIR to the ultracold atom thermometry, we study the dependence of ultracold sample temperature on the trapping beam frequency detuning. This method can be applied to determine the translational temperature of molecules in photoassociation dynamics. Project supported by the National Basic Research Development Program of China (Grant No. 2012CB921603), the National High Technology Research and Development Program of China (Grant No. 2011AA010801), the National Natural Science Foundation of China (Grant Nos. 61275209, 11304189, 61378015, and 11434007), and Program for Changjiang Scholars and Innovative Research Team in Universities of China (Grant No. IRT13076).

  4. Superconducting Nuclear Recoil Sensor for Directional Dark Matter Detection

    NASA Astrophysics Data System (ADS)

    Junghans, Ann; Baldwin, Kevin; Hehlen, Markus; Lafler, Randy; Loomba, Dinesh; Phan, Nguyen; Weisse-Bernstein, Nina

    The Universe consists of 72% dark energy, 23% dark matter and only 5% of ordinary matter. One of the greatest challenges of the scientific community is to understand the nature of dark matter. Current models suggest that dark matter is made up of slowly moving, weakly interacting massive particles (WIMPs). But detecting WIMPs is challenging, as their expected signals are small and rare compared to the large background that can mimic the signal. The largest and most robust unique signature that sets them apart from other particles is the day-night variation of the directionality of dark matter on Earth. This modulation could be observed with a direction-sensitive detector and hence, would provide an unambiguous signature for the galactic origin of WIMPs. There are many studies underway to attempt to detect WIMPs both directly and indirectly, but solid-state WIMP detectors are widely unexplored although they would present many advantages to prevalent detectors that use large volumes of low pressure gas. We present first results of a novel multi-layered architecture, in which WIMPs would interact primarily with solid layers to produce nuclear recoils that then induce measureable voltage pulses in adjacent superconductor layers. This work was supported by the U.S. Department of Energy through the LANL Laboratory Directed Research and Development Program.

  5. Identification of γ Transitions in ^176-179Hg Using the Recoil Decay Tagging Method.

    NASA Astrophysics Data System (ADS)

    Carpenter, M. P.; Ackermann, D.; Blumenthal, D.; Davids, C.; Fischer, S. M.; Hackman, G.; Janssens, R. V. F.; Khoo, T. L.; Lauritsen, T.; Lister, C. J.; Nisius, D.; Seweryniak, D.; Woods, P. J.; Amro, H.; Brown, T.; Hamilton, J. H.; Ramayya, A. V.; Reviol, W.; Schwartz, J.; Simpson, J.

    1996-05-01

    In light Hg isotopes (100<= N <= 108), shape co-existence has been established close to the ground state where rotational bands built on collective oblate and prolate shapes are observed. While this shape co-existence feature is predicted to be sustained in lighter Hg nuclei, such measurements become increasingly difficult due to the fact that the cross-sections for making these nuclei become very small (<1mb) and fission dominates (σ_fiss > 100 mb). In order to study this shape-coexistence phenomenon all the way to the proton-drip line, we have identified for the first time γ-ray transitions in ^176-179Hg using the Ayeball Ge array coupled to the Fragment Mass Analyzer. In order to assign γ transitions to a particular nuclide, the recoil decay tagging method was utilized, a technique which correlates γ-rays emitted from excited residues with the charged particle radioactivity of their decay. This work is supported by the DOE under contract W-31-109-ENG-38.

  6. Hadronic effects and observables in B →π ℓ+ℓ- decay at large recoil

    NASA Astrophysics Data System (ADS)

    Hambrock, Christian; Khodjamirian, Alexander; Rusov, Aleksey

    2015-10-01

    We calculate the amplitude of the rare flavor-changing neutral-current decay B →π ℓ+ℓ- at large recoil of the pion. The nonlocal contributions in which the weak effective operators are combined with the electromagnetic lepton-pair emission are systematically taken into account. These amplitudes are calculated at off-shell values of the lepton-pair mass squared, q2<0 , employing the operator-product expansion, QCD factorization and light-cone sum rules. The results are fitted to hadronic dispersion relations in q2, including the intermediate vector meson contributions. The dispersion relations are then used in the physical region q2>0 . Our main result is the process-dependent addition Δ C9(B π )(q2) to the Wilson coefficient C9 obtained at 4 mℓ2

  7. Observation of a resonance in B+ → K+ μ+ μ- decays at low recoil.

    PubMed

    Aaij, R; Adeva, B; Adinolfi, M; Adrover, C; Affolder, A; Ajaltouni, Z; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amerio, S; Amhis, Y; Anderlini, L; Anderson, J; Andreassen, R; Andrews, J E; Appleby, R B; Aquines Gutierrez, O; Archilli, F; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Bachmann, S; Back, J J; Baesso, C; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Bauer, Th; Bay, A; Beddow, J; Bedeschi, F; Bediaga, I; Belogurov, S; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernet, R; Bettler, M-O; van Beuzekom, M; Bien, A; Bifani, S; Bird, T; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Bowcock, T J V; Bowen, E; Bozzi, C; Brambach, T; van den Brand, J; Bressieux, J; Brett, D; Britsch, M; Britton, T; Brook, N H; Brown, H; Burducea, I; Bursche, A; Busetto, G; Buytaert, J; Cadeddu, S; Callot, O; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Campora Perez, D; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carranza-Mejia, H; Carson, L; Carvalho Akiba, K; Casse, G; Castillo Garcia, L; Cattaneo, M; Cauet, Ch; Cenci, R; Charles, M; Charpentier, Ph; Chen, P; Chiapolini, N; Chrzaszcz, M; Ciba, K; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coca, C; Coco, V; Cogan, J; Cogneras, E; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombes, M; Coquereau, S; Corti, G; Couturier, B; Cowan, G A; Cowie, E; Craik, D C; Cunliffe, S; Currie, R; D'Ambrosio, C; David, P; David, P N Y; Davis, A; De Bonis, I; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Silva, W; De Simone, P; Decamp, D; Deckenhoff, M; Del Buono, L; Déléage, N; Derkach, D; Deschamps, O; Dettori, F; Di Canto, A; Dijkstra, H; Dogaru, M; Donleavy, S; Dordei, F; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dupertuis, F; Durante, P; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; van Eijk, D; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; El Rifai, I; Elsasser, Ch; Falabella, A; Färber, C; Fardell, G; Farinelli, C; Farry, S; Ferguson, D; Fernandez Albor, V; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fiore, M; Fitzpatrick, C; Fontana, M; Fontanelli, F; Forty, R; Francisco, O; Frank, M; Frei, C; Frosini, M; Furcas, S; Furfaro, E; Gallas Torreira, A; Galli, D; Gandelman, M; Gandini, P; Gao, Y; Garofoli, J; Garosi, P; Garra Tico, J; Garrido, L; Gaspar, C; Gauld, R; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gibson, V; Giubega, L; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gorbounov, P; Gordon, H; Gotti, C; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Griffith, P; Grünberg, O; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hall, S; Hamilton, B; Hampson, T; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; Hartmann, T; He, J; Head, T; Heijne, V; Hennessy, K; Henrard, P; Hernando Morata, J A; van Herwijnen, E; Hess, M; Hicheur, A; Hicks, E; Hill, D; Hoballah, M; Hombach, C; Hopchev, P; Hulsbergen, W; Hunt, P; Huse, T; Hussain, N; Hutchcroft, D; Hynds, D; Iakovenko, V; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jans, E; Jaton, P; Jawahery, A; Jing, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Kaballo, M; Kandybei, S; Kanso, W; Karacson, M; Karbach, T M; Kenyon, I R; Ketel, T; Keune, A; Khanji, B; Kochebina, O; Komarov, I; Koopman, R F; Koppenburg, P; Korolev, M; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kucharczyk, M; Kudryavtsev, V; Kurek, K; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanciotti, E; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J-P; Lefèvre, R; Leflat, A; Lefrançois, J; Leo, S; Leroy, O; Lesiak, T; Leverington, B; Li, Y; Li Gioi, L; Liles, M; Lindner, R; Linn, C; Liu, B; Liu, G; Lohn, S; Longstaff, I; Lopes, J H; Lopez-March, N; Lu, H; Lucchesi, D; Luisier, J; Luo, H; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Malde, S; Manca, G; Mancinelli, G; Maratas, J; Marconi, U; Marino, P; Märki, R; Marks, J; Martellotti, G; Martens, A; Martín Sánchez, A; Martinelli, M; Martinez Santos, D; Martins Tostes, D; Martynov, A; Massafferri, A; Matev, R; Mathe, Z; Matteuzzi, C; Maurice, E; Mazurov, A; McCarthy, J; McNab, A; McNulty, R; McSkelly, B; Meadows, B; Meier, F; Meissner, M; Merk, M; Milanes, D A; Minard, M-N; Molina Rodriguez, J; Monteil, S; Moran, D; Morawski, P; Mordà, A; Morello, M J; Mountain, R; Mous, I; Muheim, F; Müller, K; Muresan, R; Muryn, B; Muster, B; Naik, P; Nakada, T; Nandakumar, R; Nasteva, I; Needham, M; Neubert, S; Neufeld, N; Nguyen, A D; Nguyen, T D; Nguyen-Mau, C; Nicol, M; Niess, V; Niet, R; Nikitin, N; Nikodem, T; Nomerotski, A; Novoselov, A; Oblakowska-Mucha, A; Obraztsov, V; Oggero, S; Ogilvy, S; Okhrimenko, O; Oldeman, R; Orlandea, M; Otalora Goicochea, J M; Owen, P; Oyanguren, A; Pal, B K; Palano, A; Palczewski, T; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Parkes, C; Parkinson, C J; Passaleva, G; Patel, G D; Patel, M; Patrick, G N; Patrignani, C; Pavel-Nicorescu, C; Pazos Alvarez, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perez Trigo, E; Pérez-Calero Yzquierdo, A; Perret, P; Perrin-Terrin, M; Pescatore, L; Pesen, E; Petridis, K; Petrolini, A; Phan, A; Picatoste Olloqui, E; Pietrzyk, B; Pilař, T; Pinci, D; Playfer, S; Plo Casasus, M; Polci, F; Polok, G; Poluektov, A; Polycarpo, E; Popov, A; Popov, D; Popovici, B; Potterat, C; Powell, A; Prisciandaro, J; Pritchard, A; Prouve, C; Pugatch, V; Puig Navarro, A; Punzi, G; Qian, W; Rademacker, J H; Rakotomiaramanana, B; Rangel, M S; Raniuk, I; Rauschmayr, N; Raven, G; Redford, S; Reid, M M; dos Reis, A C; Ricciardi, S; Richards, A; Rinnert, K; Rives Molina, V; Roa Romero, D A; Robbe, P; Roberts, D A; Rodrigues, E; Rodriguez Perez, P; Roiser, S; Romanovsky, V; Romero Vidal, A; Rouvinet, J; Ruf, T; Ruffini, F; Ruiz, H; Ruiz Valls, P; Sabatino, G; Saborido Silva, J J; Sagidova, N; Sail, P; Saitta, B; Salustino Guimaraes, V; Sanmartin Sedes, B; Sannino, M; Santacesaria, R; Santamarina Rios, C; Santovetti, E; Sapunov, M; Sarti, A; Satriano, C; Satta, A; Savrie, M; Savrina, D; Schaack, P; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmidt, B; Schneider, O; Schopper, A; Schune, M-H; Schwemmer, R; Sciascia, B; Sciubba, A; Seco, M; Semennikov, A; Senderowska, K; Sepp, I; Serra, N; Serrano, J; Seyfert, P; Shapkin, M; Shapoval, I; Shatalov, P; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, O; Shevchenko, V; Shires, A; Silva Coutinho, R; Sirendi, M; Skidmore, N; Skwarnicki, T; Smith, N A; Smith, E; Smith, J; Smith, M; Sokoloff, M D; Soler, F J P; Soomro, F; Souza, D; Souza De Paula, B; Spaan, B; Sparkes, A; Spradlin, P; Stagni, F; Stahl, S; Steinkamp, O; Stevenson, S; Stoica, S; Stone, S; Storaci, B; Straticiuc, M; Straumann, U; Subbiah, V K; Sun, L; Swientek, S; Syropoulos, V; Szczekowski, M; Szczypka, P; Szumlak, T; T'Jampens, S; Teklishyn, M; Teodorescu, E; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Tolk, S; Tonelli, D; Topp-Joergensen, S; Torr, N; Tournefier, E; Tourneur, S; Tran, M T; Tresch, M; Tsaregorodtsev, A; Tsopelas, P; Tuning, N; Ubeda Garcia, M; Ukleja, A; Urner, D; Ustyuzhanin, A; Uwer, U; Vagnoni, V; Valenti, G; Vallier, A; Van Dijk, M; Vazquez Gomez, R; Vazquez Regueiro, P; Vázquez Sierra, C; Vecchi, S; Velthuis, J J; Veltri, M; Veneziano, G; Vesterinen, M; Viaud, B; Vieira, D; Vilasis-Cardona, X; Vollhardt, A; Volyanskyy, D; Voong, D; Vorobyev, A; Vorobyev, V; Voß, C; Voss, H; Waldi, R; Wallace, C; Wallace, R; Wandernoth, S; Wang, J; Ward, D R; Watson, N K; Webber, A D; Websdale, D; Whitehead, M; Wicht, J; Wiechczynski, J; Wiedner, D; Wiggers, L; Wilkinson, G; Williams, M P; Williams, M; Wilson, F F; Wimberley, J; Wishahi, J; Wislicki, W; Witek, M; Wotton, S A; Wright, S; Wu, S; Wyllie, K; Xie, Y; Xing, Z; Yang, Z; Young, R; Yuan, X; Yushchenko, O; Zangoli, M; Zavertyaev, M; Zhang, F; Zhang, L; Zhang, W C; Zhang, Y; Zhelezov, A; Zhokhov, A; Zhong, L; Zvyagin, A

    2013-09-13

    A broad peaking structure is observed in the dimuon spectrum of B+ → K+ μ+ μ- decays in the kinematic region where the kaon has a low recoil against the dimuon system. The structure is consistent with interference between the B+ → K+ μ+ μ- decay and a resonance and has a statistical significance exceeding six standard deviations. The mean and width of the resonance are measured to be 4191(-8)(+9)  MeV/c2 and 65(-16)(+22)  MeV/c2, respectively, where the uncertainties include statistical and systematic contributions. These measurements are compatible with the properties of the ψ(4160) meson. First observations of both the decay B+ → ψ(4160)K+ and the subsequent decay ψ(4160) → μ+ μ- are reported. The resonant decay and the interference contribution make up 20% of the yield for dimuon masses above 3770  MeV/c2. This contribution is larger than theoretical estimates. PMID:24074076

  8. First measurement of the ionization yield of nuclear recoils in liquid argon

    SciTech Connect

    Joshi, T.; Sangiorgio, Samuele; Bernstein, A.; Foxe, Michael P.; Hagmann, Chris; Jovanovic, Igor; Kazkaz, K.; Mozin, Vladimir V.; Norman, E. B.; Pereverzev, S. V.; Rebassoo, Finn O.; Sorensen, Peter F.

    2014-05-01

    Liquid phase argon has long been used as a target medium for particle detection via scintillation light. Recently there has been considerable interest in direct detection of both hypothetical darkmatter particles and coherent elastic neutrino nucleus scattering. These as-yet unobserved neutral particle interactions are expected to result in a recoiling argon atom O(keV), generally referred to in the literature as a nuclear recoil. This prompts the question of the available electromagnetic signal in a liquid argon detector. In this Letter we report the first measurement of the ionization yield (Qy), detected electrons per unit energy, resulting from nuclear recoils in liquid argon, measured at 6.7 keV. This is also the lowest energy measurement of nuclear recoils in liquid argon.

  9. Further insights into the proton spin with the new HERMES Recoil Detector

    SciTech Connect

    Vilardi, I.

    2007-11-19

    The HERMES experiment, installed in the 27.5 GeV HERA lepton ring at DESY/Hamburg, is used to study the spin structure of the nucleon. To get information about the orbital angular momentum L{sub q} of quarks, exclusive DIS reactions are investigated. The HERMES Collaboration installed a new Recoil Detector to upgrade the existing spectrometer to improve the study of hard exclusive processes, detecting recoil protons with low momentum. Deeply Virtual Compton Scattering is the main process to be studied. The HERMES Recoil Detector consists of three subcomponents inside a superconducting magnet that provides a longitudinal superconducting magnetic field of 1 Tesla. The Recoil Detector was installed in January 2006 and commissioning started in February. First results from the detector will be presented.

  10. Element-specific recoil loops in Sm-Co/Fe exchange-spring magnets.

    SciTech Connect

    Choi, Y.; Jiang, J. S.; Pearson, J. E.; Bader, S. D.; Liu, J. P.; Materials Science Division; Univ. Texas at Arlington

    2008-04-01

    In two-phase nanocomposite magnets, open recoil loops have shown to be sensitive to interphase interfacial conditions and have been often used to characterize the interphase exchange coupling. Typically, the open recoil loops are attributed to the soft phase volume that is decoupled from the hard phase. Our element-specific magnetic measurements on bilayer Sm-Co/Fe exchange-spring magnets reveal that open recoil loops are present not only in the soft Fe layer but also in the hard Sm-Co layer and that the Fe- and Sm-specific remanence curves are similar to each other. The experimental results and micromagnetic modeling reveal that the observed open recoil loops can originate from the anisotropy variations in the hard Sm-Co layer.

  11. A telescope proton recoil spectrometer for fast neutron beam-lines

    NASA Astrophysics Data System (ADS)

    Cazzaniga, C.; Rebai, M.; Tardocchi, M.; Croci, G.; Nocente, M.; Ansell, S.; Frost, C. D.; Gorini, G.

    2015-07-01

    Fast neutron measurements were performed on the VESUVIO beam-line at the ISIS spallation source using a new telescope proton recoil spectrometer. Neutrons interact on a plastic target. Proton production is mainly due to elastic scattering on hydrogen nuclei and secondly due to interaction with carbon nuclei. Recoil protons are measured by a proton spectrometer, which uses in coincidence a 2.54 cm thick YAP scintillator and a 500μm thick silicon detector, measuring the full proton recoil energy and the partial deposited energy in transmission, respectively. Recoil proton spectroscopy measurements (up to Ep = 60MeV) have been interpreted by using Monte Carlo simulations of the beam-line. This instrument is of particular interest for the characterization of the ChipIr beam-line at ISIS, which was designed to feature an atmospheric-like neutron spectrum for the irradiation of micro-electronics.

  12. The non-Newtonian heat and mass transport of He 2 in porous media used for vapor-liquid phase separation. Ph.D. Thesis

    NASA Technical Reports Server (NTRS)

    Yuan, S. W. K.

    1985-01-01

    This investigation of vapor-liquid phase separation (VLPS) of He 2 is related to long-term storage of cryogenic liquid. The VLPS system utilizes porous plugs in order to generate thermomechanical (thermo-osmotic) force which in turn prevents liquid from flowing out of the cryo-vessel (e.g., Infrared Astronomical Satellite). An apparatus was built and VLPS data were collected for a 2 and a 10 micrometer sintered stainless steel plug and a 5 to 15 micrometer sintered bronze plug. The VLPS data obtained at high temperature were in the nonlinear turbulent regime. At low temperature, the Stokes regime was approached. A turbulent flow model was developed, which provides a phenomenological description of the VLPS data. According to the model, most of the phase separation data are in the turbulent regime. The model is based on concepts of the Gorter-Mellink transport involving the mutual friction known from the zero net mass flow (ZNMF) studies. The latter had to be modified to obtain agreement with the present experimental VLPS evidence. In contrast to the well-known ZNMF mode, the VLPS results require a geometry dependent constant (Gorter-Mellink constant). A theoretical interpretation of the phenomenological equation for the VLPS data obtained, is based on modelling of the dynamics of quantized vortices proposed by Vinen. In extending Vinen's model to the VLPS transport of He 2 in porous media, a correlation between the K*(GM) and K(p) was obtained which permits an interpretation of the present findings. As K(p) is crucial, various methods were introduced to measure the permeability of the porous media at low temperatures. Good agreement was found between the room temperature and the low temperature K(p)-value of the plugs.

  13. Separation of isomeric short-chain acyl-CoAs in plant matrices using ultra-performance liquid chromatography coupled with tandem mass spectrometry.

    PubMed

    Purves, Randy W; Ambrose, Stephen J; Clark, Shawn M; Stout, Jake M; Page, Jonathan E

    2015-02-01

    Acyl coenzyme A (acyl-CoA) thioesters are important intermediates in cellular metabolism and being able to distinguish among them is critical to fully understanding metabolic pathways in plants. Although significant advances have been made in the identification and quantification of acyl-CoAs using liquid chromatography tandem mass spectrometry (LC-MS/MS), separation of isomeric species such as isobutyryl- and n-butyrl-CoA has remained elusive. Here we report an ultra-performance liquid chromatography (UPLC)-MS/MS method for quantifying short-chain acyl-CoAs including isomeric species n-butyryl-CoA and isobutyryl-CoA as well as n-valeryl-CoA and isovaleryl-CoA. The method was applied to the analysis of extracts of hop (Humulus lupulus) and provided strong evidence for the existence of an additional structural isomer of valeryl-CoA, 2-methylbutyryl-CoA, as well as an unexpected isomer of hexanoyl-CoA. The results showed differences in the acyl-CoA composition among varieties of Humulus lupulus, both in glandular trichomes and cone tissues. When compared with the analysis of hemp (Cannabis sativa) extracts, the contribution of isobutyryl-CoAs in hop was greater as would be expected based on the downstream polyketide products. Surprisingly, branched chain valeryl-CoAs (isovaleryl-CoA and 2-methylbutyryl-CoA) were the dominant form of valeryl-CoAs in both hop and hemp. The capability to separate these isomeric forms will help to understand biochemical pathways leading to specialized metabolites in plants. PMID:25553535

  14. As-Al recoil implantation through Si 3N 4 barrier layer

    NASA Astrophysics Data System (ADS)

    Godignon, P.; Morvan, E.; Montserrat, J.; Jordà, X.; Flores, D.; Rebollo, J.

    1999-01-01

    Al recoil implantation have been shown to be a possible alternative to direct Al ion implantation to avoid usual problems linked with Al sources. Poor efficiency of the recoil + annealing process is observed if no barrier or an oxyde screen layers are used. This problem can be solved using a Si 3N 4 screen layer. Then, P-N and N +/P/N structures can be obtained with deep low doped P-well with reduced thermal budget.

  15. Investigation on modeling and controability of a magnetorheological gun recoil damper

    NASA Astrophysics Data System (ADS)

    Hu, Hongsheng; Wang, Juan; Wang, Jiong; Qian, Suxiang; Li, Yancheng

    2009-07-01

    Magnetorheological (MR) fluid as a new smart material has done well in the vibration and impact control engineering fields because of its good electromechanical coupling characteristics, preferable dynamic performance and higher sensitivity. And success of MRF has been apparent in many engineering applied fields, such as semi-active suspension, civil engineering, etc. So far, little research has been done about MR damper applied into the weapon system. Its primary purpose of this study is to identify its dynamic performance and controability of the artillery recoil mechanism equipped with MR damper. Firstly, based on the traditional artillery recoil mechanism, a recoil dynamic model is developed in order to obtain an ideal rule between recoil force and its stroke. Then, its effects of recoil resistance on the stability and firing accuracy of artillery are explored. Because MR gun recoil damper under high impact load shows a typical nonlinear character and there exists a shear-thinning phenomenon, to establish an accurate dynamic model has been a seeking aim of its design and application for MR damper under high impact load. Secondly, in this paper, considering its actual bearing load, an inertia factor was introduced to Herschel-Bulkley model, and some factor's effect on damping force are simulated and analyzed by using numerical simulation, including its dynamic performance under different flow coefficients and input currents. Finally, both of tests with the fixed current and different On-Off control algorithms have been done to confirm its controability of MR gun recoil damper under high impact load. Experimental results show its dynamic performances of the large-scale single-ended MR gun recoil damper can be changed by altering the applied currents and it has a good controllability.

  16. Acute stent recoil in the left main coronary artery treated with additional stenting.

    PubMed

    Battikh, Kais; Rihani, Riadh; Lemahieu, Jean Michel

    2003-01-01

    We report a case of acute stent recoil occurring after the stenting of an ostial left main coronary artery lesion. The marked recoil after high-pressure balloon inflation confirmed that the radial force of the first stent was unable to ensure vessel patency. The addition of a second stent provided the necessary support to achieve a good final result. This case illustrates a possible complication of aorto-ostial angioplasty that could be treated with double stenting. PMID:12499528

  17. Influence of elastic recoil on restenosis after successful coronary angioplasty in unstable angina pectoris.

    PubMed

    Ardissino, D; Di Somma, S; Kubica, J; Barberis, P; Merlini, P A; Eleuteri, E; De Servi, S; Bramucci, E; Specchia, G; Montemartini, C

    1993-03-15

    The elastic behavior of the dilated coronary vessel has been reported to affect the immediate results of coronary angioplasty. To determine whether elastic recoil may also influence the long-term restenosis process, 98 consecutive patients with unstable angina and 1-vessel disease were studied. An automated coronary quantitative program was used for the assessment of balloon and coronary luminal diameters. Elastic recoil was defined as the percent reduction between minimal balloon diameter at the highest inflation pressure and minimal lesion diameter immediately after coronary angioplasty. Follow-up coronary arteriography was performed 8 to 12 months after the procedure in all patients. The mean elastic recoil averaged 17.7 +/- 16% and was correlated to the degree of residual stenosis immediately after coronary angioplasty (r = 0.64; p < 0.001). Restenosis, defined as > 50% diameter stenosis at follow-up, developed in 53 patients (54%). There was no correlation between the degree of elastic recoil and the changes in minimal lesion diameter observed during follow-up, whereas a positive correlation between the amount of elastic recoil and the incidence of restenosis was documented (r = 0.84; p < 0.05). Thus, the elastic properties of the dilated vessel do not influence the active process of restenosis. However, because elastic recoil negatively influences the initial results of angioplasty, it is more likely that further reductions in lumen diameter during follow-up can reach a threshold of obstruction considered critical for a binary definition of restenosis. PMID:8447261

  18. Separation and characterization of oligomeric hindered amine light stabilizers using high-performance liquid chromatography with UV and quadrupole time-of-flight mass spectrometric detection.

    PubMed

    Hintersteiner, Ingrid; Reisinger, Michael; Himmelsbach, Markus; Buchberger, Wolfgang

    2016-03-01

    Hindered amine light stabilizers are an important class of stabilizers that protect synthetic polymers from degradation and thus from changing mechanical and optical properties. The current study presents an HPLC method capable of separating oligomeric hindered amine light stabilizers on a commercially available stationary phase, employing an MS-compatible novel mobile phase. Based on the exact masses observed with Q-TOF-MS, a comprehensive characterization of five different types of oligomeric hindered amine light stabilizers was achieved, leading to structural information not included in the datasheets provided by the suppliers. For the different investigated hindered amine light stabilizers, a number of recurring units up to 17 and a molecular weight of 5200 g/mol were detected. Furthermore, the analysis of stabilizer extracts of processed polypropylene samples containing different types of hindered amine light stabilizers revealed significant differences in the oligomeric pattern between standards and polymer samples. Thus, changes in the analytes' oligomeric pattern resulting from processing or aging of polymer materials can be monitored with the presented method. PMID:26778637

  19. Using electrospray-assisted laser desorption/ionization mass spectrometry to characterize organic compounds separated on thin-layer chromatography plates.

    PubMed

    Lin, Shu-Yao; Huang, Min-Zong; Chang, Hui-Chiu; Shiea, Jentaie

    2007-11-15

    Electrospray-assisted laser desorption/ionization (ELDI), an ionization method that combines laser desorption and electrospray ionization (ESI), can be used under ambient conditions to characterize organic compounds (including FD&C dyes, amines, extracts of a drug tablet) separated in the central track on a thin-layer chromatography (TLC) plate coated with either reversed-phase C18 particles or normal-phase silica gel. After drying, the TLC plate was placed on an acrylic sample holder set in front of the sampling skimmer of an ion trap mass analyzer. The chemicals at the center of the TLC plate were analyzed by pushing the sample holder into the path of a laser beam with a syringe pump. The molecules in the sample spot were desorbed by continuously irradiating the surface of the TLC plate with a pulsed nitrogen laser. Then, the desorbed sample molecules entered an ESI plume where they were ionized through the reactions with the charged species (including protons, hydronium ions and their cluster ions, solvent ions, and charged droplets) generated by electrospraying a methanol/water solution. MS/MS analyses were also performed to further characterize the analytes. The detection limit of TLC/ELDI/MS is approximately 10(-6) M. This was evaluated by using FD&C red dye as the standard. A linear relationship was found for the calibration curve with the concentration of FD&C red dye ranged from 10(-3) to 10(-6) M. PMID:17929897

  20. Investigation of natural phosphatidylcholine sources: separation and identification by liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS2) of molecular species.

    PubMed

    Le Grandois, Julie; Marchioni, Eric; Zhao, Minjie; Giuffrida, Francesca; Ennahar, Saïd; Bindler, Françoise

    2009-07-22

    This study is a contribution to the exploration of natural phospholipid (PL) sources rich in long-chain polyunsaturated fatty acids (LC-PUFAs) with nutritional interest. Phosphatidylcholines (PCs) were purified from total lipid extracts of different food matrices, and their molecular species were separated and identified by liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS(2)). Fragmentation of lithiated adducts allowed for the identification of fatty acids linked to the glycerol backbone. Soy PC was particularly rich in species containing essential fatty acids, such as (18:2-18:2)PC (34.0%), (16:0-18:2)PC (20.8%), and (18:1-18:2)PC (16.3%). PC from animal sources (ox liver and egg yolk) contained major molecular species, such as (16:0-18:2)PC, (16:0-18:1)PC, (18:0-18:2)PC, or (18:0-18:1)PC. Finally, marine source (krill oil), which was particularly rich in (16:0-20:5)PC and (16:0-22:6)PC, appeared to be an interesting potential source for food supplementation with LC-PUFA-PLs, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). PMID:19545117

  1. Determination of Os by isotope dilution-inductively coupled plasma-mass spectrometry with the combination of laser ablation to introduce chemically separated geological samples

    NASA Astrophysics Data System (ADS)

    Sun, Yali; Ren, Minghao; Xia, Xiaoping; Li, Congying; Sun, Weidong

    2015-11-01

    A method was developed for the determination of trace Os in geological samples by laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) with the combination of chemical separation and preconcentration. Samples are digested using aqua regia in Carius tubes, and the Os analyte is converted into volatile OsO4, which is distilled and absorbed with HBr. The HBr solution is concentrated for further Os purification using the microdistillation technique. The purified Os is dissolved in 10 μl of 0.02% sucrose-0.005% H3PO4 solution and then evaporated on pieces of perfluoroalkoxy (PFA) film, resulting in the formation of a tiny object (< 3 × 104 μm2 superficial area). Using LA-ICP-MS measurements, the object can give Os signals at least 100 times higher than those provided by routine solution-ICP-MS while successfully avoiding the memory effect. The procedural blank and detection limit in the developed technique are 3.0 pg and 1.8 pg for Os, respectively when 1 g of samples is taken. Reference materials (RM) are analyzed, and their Os concentrations obtained by isotope dilution are comparable to reference or literature values. Based on the individual RM results, the precision is estimated within the range of 0.6 to 9.4% relative standard deviation (RSD), revealing that this method is applicable to the determination of trace Os in geological samples.

  2. Separation and analysis of trace volatile formaldehyde in aquatic products by a MoO₃/polypyrrole intercalative sampling adsorbent with thermal desorption gas chromatography and mass spectrometry.

    PubMed

    Ma, Yunjian; Zhao, Cheng; Zhan, Yisen; Li, Jianbin; Zhang, Zhuomin; Li, Gongke

    2015-05-01

    An in situ embedded synthesis strategy was developed for the preparation of a MoO3 /polypyrrole intercalative sampling adsorbent for the separation and analysis of trace volatile formaldehyde in aquatic products. Structural and morphological characteristics of the MoO3 /polypyrrole intercalative adsorbent were investigated by a series of characterization methods. The MoO3 /polypyrrole sampling adsorbent possessed a higher sampling capacity and selectivity for polar formaldehyde than commonly used commercial adsorbent Tenax TA. Finally, the MoO3 /polypyrrole adsorbent was packed in the thermal desorption tube that was directly coupled to gas chromatography with mass spectrometry for the analysis of trace volatile formaldehyde in aquatic products. Trace volatile formaldehyde from real aquatic products could be selectively sampled and quantified to be 0.43-6.6 mg/kg. The detection limit was achieved as 0.004 μg/L by this method. Good recoveries for spiked aquatic products were achieved in range of 75.0-108% with relative standard deviations of 1.2-9.0%. PMID:25677048

  3. Separation and characterization of metallothionein in the liver of sea turtles by high performance liquid chromatographylinductively coupled plasma-mass spectrometry

    NASA Astrophysics Data System (ADS)

    Shinsuke, T.; Yasumi, A.; Takashi, K.

    2003-05-01

    To investigate whether trace metals bind to metallothioneins (MTs) in the hepatocytosol of green turtles (Chelonia mydas) and hawksbill turtles (Eretmochelys imbricata), MT fraction was obtained by ultracentrifugation and gel filtration methods. MTs separated from hepatocytosol were further purified and characterized by high performance liquid chromatography/inductively coupled plasma-mass spectrometry. In addition, the involvement of MTs in the accumulation of trace metals in the liver of sea turtle was examine. Gel filtration analysis showed that significant amounts of Cu, Zn, Ag and Cd were bound to MT in the cytosol of sea turtles, suggesting that such trace metals were primarily detoxified by interaction with MTs in the liver. Elution profiles of these trace metals by anion-exchange chromatography were different between green turtles and hawksbill turtles. These results suggest the presence of multiple isoforms of MT in the liver of both sea turtles; however, constituents of isoforms were different between green and hawksbill turtles. In both species, we observed the elevation of the height of a specific peak in elution profile with an increase in Cu concentration in hepatocytosol. This result suggests the presence of a novel MT isoform related to copper accumulation in the liver of sea turtles.

  4. A novelty strategy for the fast analysis of sulfonamide antibiotics in fish tissue using magnetic separation with high-performance liquid chromatography-tandem mass spectrometry.

    PubMed

    Li, Jincheng; Liu, Huan; Zhang, Jing; Liu, Yang; Wu, Lidong

    2016-08-01

    A simple, fast and low-cost extraction method with high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) determination was developed on sulfonamide antibiotics (SAs) in fish tissue. Magnetic separation was first introduced into the rapid sample preparation procedure combined with acetonitrile extraction for the analysis of SAs. Partitioning was rapidly achieved between acetonitrile solution and solid matrix by applying an external magnetic field. Acetonitrile solution was collected and concentrated under a nitrogen stream. The residue was redissolved with 1‰ formic acid aqueous solution and defatted with n-hexane before analysis. The recoveries of SAs were in the range of 74.87-104.74%, with relative standard deviations <13%. The limits of quantification and the limits of detection for SAs ranged from 5.0 to 25.0 μg (kg-1) and from 2.5 to 10.0 μg (kg-1) , respectively. The presented extraction method proved to be a rapid method which only took 20 min for one sample preparation procedure. Copyright © 2016 John Wiley & Sons, Ltd. PMID:26849706

  5. Measurements of fission yields in the heavy region at the recoil ass spectrometer lohengrin

    NASA Astrophysics Data System (ADS)

    Bail, A.; Serot, O.; Mathieu, L.; Litaize, O.; Materna, T.; Köster, U.; Faust, H.; Letourneau, A.; Panebianco, S.; Dupont, E.; Michel-Sendis, F.

    2009-10-01

    In spite of the huge amount of fission yield data available in different libraries, more accurate values are still needed for nuclear energy applications and to improve our understanding of the fission process. Thus measurements of fission yields were performed at the mass spectrometer Lohengrin at the Institut Laue-Langevin in Grenoble, France. The mass separator Lohengrin is situated at the research reactor of the institute and permits the placement of an actinide layer in a high thermal neutron flux. It separates fragments according to their atomic mass, kinetic energy and ionic charge state by the action of magnetic and electric fields. Coupled to a high resolution ionization chamber the experiment was used to investigate the mass and isotopic yields in the light mass region. Almost all fission yields of isotopes from Th to Cf have been measured at Lohengrin with this method. It has been extended in this work to the heavy mass region for the reactions 235U(nth,f), 239Pu(nth,f), and 241Pu(nth,f). For these higher masses an isotopic separation is no longer possible. So, a new method was undertaken with the reaction 239Pu(nth,f) to determine the isotopic yields by γ spectrometry. The results are presented in this paper.

  6. Measurement of Scintillation and Ionization Yield and Scintillation Pulse Shape from Nuclear Recoils in Liquid Argon

    SciTech Connect

    Cao, H.

    2015-05-26

    We have measured the scintillation and ionization yield of recoiling nuclei in liquid argon as a function of applied electric field by exposing a dual-phase liquid argon time projection chamber (LAr-TPC) to a low energy pulsed narrow band neutron beam produced at the Notre Dame Institute for Structure and Nuclear Astrophysics. Liquid scintillation counters were arranged to detect and identify neutrons scattered in the TPC and to select the energy of the recoiling nuclei. We also report measurements of the scintillation yields for nuclear recoils with energies from 10.3 to 57.3 keV and for median applied electric fields from 0 to 970 V/cm. For the ionization yields, we report measurements from 16.9 to 57.3 keV and for electric fields from 96.4 to 486 V/cm. Furthermore, we report the observation of an anticorrelation between scintillation and ionization from nuclear recoils, which is similar to the anticorrelation between scintillation and ionization from electron recoils. Assuming that the energy loss partitions into excitons and ion pairs from 83mKr internal conversion electrons is comparable to that from 207Bi conversion electrons, we obtained the numbers of excitons (Nex) and ion pairs (Ni) and their ratio (Nex/Ni) produced by nuclear recoils from 16.9 to 57.3 keV. Motivated by arguments suggesting direction sensitivity in LAr-TPC signals due to columnar recombination, a comparison of the light and charge yield of recoils parallel and perpendicular to the applied electric field is presented for the first time.

  7. Measurement of Scintillation and Ionization Yield and Scintillation Pulse Shape from Nuclear Recoils in Liquid Argon

    DOE PAGESBeta

    Cao, H.

    2015-05-26

    We have measured the scintillation and ionization yield of recoiling nuclei in liquid argon as a function of applied electric field by exposing a dual-phase liquid argon time projection chamber (LAr-TPC) to a low energy pulsed narrow band neutron beam produced at the Notre Dame Institute for Structure and Nuclear Astrophysics. Liquid scintillation counters were arranged to detect and identify neutrons scattered in the TPC and to select the energy of the recoiling nuclei. We also report measurements of the scintillation yields for nuclear recoils with energies from 10.3 to 57.3 keV and for median applied electric fields from 0more » to 970 V/cm. For the ionization yields, we report measurements from 16.9 to 57.3 keV and for electric fields from 96.4 to 486 V/cm. Furthermore, we report the observation of an anticorrelation between scintillation and ionization from nuclear recoils, which is similar to the anticorrelation between scintillation and ionization from electron recoils. Assuming that the energy loss partitions into excitons and ion pairs from 83mKr internal conversion electrons is comparable to that from 207Bi conversion electrons, we obtained the numbers of excitons (Nex) and ion pairs (Ni) and their ratio (Nex/Ni) produced by nuclear recoils from 16.9 to 57.3 keV. Motivated by arguments suggesting direction sensitivity in LAr-TPC signals due to columnar recombination, a comparison of the light and charge yield of recoils parallel and perpendicular to the applied electric field is presented for the first time.« less

  8. A Geochemical Mass-Balance Method for Base-Flow Separation, Upper Hillsborough River Watershed, West-Central Florida, 2003-2005 and 2009

    USGS Publications Warehouse

    Kish, G.R.; Stringer, C.E.; Stewart, M.T.; Rains, M.C.; Torres, A.E.

    2010-01-01

    Geochemical mass-balance (GMB) and conductivity mass-balance (CMB) methods for hydrograph separation were used to determine the contribution of base flow to total stormflow at two sites in the upper Hillsborough River watershed in west-central Florida from 2003-2005 and at one site in 2009. The chemical and isotopic composition of streamflow and precipitation was measured during selected local and frontal low- and high-intensity storm events and compared to the geochemical and isotopic composition of groundwater. Input for the GMB method included cation, anion, and stable isotope concentrations of surface water and groundwater, whereas input for the CMB method included continuous or point-sample measurement of specific conductance. The surface water is a calcium-bicarbonate type water, which closely resembles groundwater geochemically, indicating that much of the surface water in the upper Hillsborough River basin is derived from local groundwater discharge. This discharge into the Hillsborough River at State Road 39 and at Hillsborough River State Park becomes diluted by precipitation and runoff during the wet season, but retains the calcium-bicarbonate characteristics of Upper Floridan aquifer water. Field conditions limited the application of the GMB method to low-intensity storms but the CMB method was applied to both low-intensity and high-intensity storms. The average contribution of base flow to total discharge for all storms ranged from 31 to 100 percent, whereas the contribution of base flow to total discharge during peak discharge periods ranged from less than 10 percent to 100 percent. Although calcium, magnesium, and silica were consistent markers of Upper Floridan aquifer chemistry, their use in calculating base flow by the GMB method was limited because the frequency of point data collected in this study was not sufficient to capture the complete hydrograph from pre-event base-flow to post-event base-flow concentrations. In this study, pre-event water

  9. EFFECT OF LASER LIGHT ON MATTER. LASER PLASMAS: Recoil momentum at a solid surface during developed laser ablation

    NASA Astrophysics Data System (ADS)

    Kuznetsov, L. I.

    1993-12-01

    The recoil momentum from a laser light pulse in the intensity range 105-107 W/cm2 is experimentally investigated for dielectric and metallic targets as a function of the pressure of the surrounding medium and angle of illumination. An equation with empirical coefficients is obtained for the recoil momentum of illuminated targets. Effects of the screening properties of the erosion jet and the back pressure on the recoil momentum are analyzed as the external pressure is varied.

  10. Separation and determination of diversiform phytosterols in food materials using supercritical carbon dioxide extraction and ultraperformance liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry.

    PubMed

    Lu, Baiyi; Zhang, Ying; Wu, Xiaoqin; Shi, Jiayi

    2007-04-01

    This paper presents at first time that the ultra-performance liquid chromatographic atmospheric pressure chemical ionization mass spectrometer (UPLC-APCI-MS) was used as an efficient method for the identification and quantification of diversiform phytosterols in food materials. The sample preparation consisted of extraction by supercritical carbon dioxide fluid extraction (SCE) and saponification by refluxing with ethanolic KOH, and then the non-saponificable fraction was extracted with petroleum ether. This fraction was subjected to solid phase extraction (SPE) on silica gel cartridge and then the sterols were eluted with hexane-ethyl acetate. Sterols were separated on an Acquity UPLC BEH C18 column (100 mm x 1.0 mm, 1.7 microm particle size) with a gradient of methanol/water (1% acetonitrile) at a flow of 0.1 mL min(-1). The determination was performed in selective ion monitoring mode. The quality parameter of the developed method was established using 6-ketocholestanol as internal standard. Limits of quantification (LOQ) were 0.1754, 0.0341, 0.0500, 0.0205, 0.0225, 0.3674, 0.0241, 0.0272, 0.0076 microg L(-1) and 0.1525 microg mL(-1) for 6-ketocholestanol, desmosterol, ergosterol, cholesterol, lanosterol, cholestanol, campesterol, stigmasterol, beta-sitosterol, and stigmastanol, respectively. The intra- and inter-day determination precision for the 10 phytosterols were less than 5 and 6% in relative standard deviations, and their recoveries were located in the range of 94-107%. The developed approach has been applied successfully for efficient determination of diversiform phytosterols in food materials, including corn, sesame, oat and peanut. PMID:17386793

  11. Determination of boron in high-purity tantalum materials by on-line matrix separation/inductively coupled plasma mass spectrometry.

    PubMed

    Kozono, Shuji; Takahashi, Shigeto; Haraguchi, Hiroki

    2002-07-01

    A method for the determination of ultratrace amounts of boron in high-purity tantalum materials [tantalum metal, tantalum(v) oxide, tantalum pentachloride and tantalum pentaethoxide] is described. On-line anion-exchange matrix separation combined with inductively coupled plasma mass spectrometry (ICP-MS) was employed for the determination of boron at the ng g(-1) level. Tantalum materials were dissolved using HF and/or HNO3 prior to analysis. The loss of boron in the sample preparation procedure was examined as the recovery of boron by adding a definite amount of boron to each tantalum material sample before decomposition, and it was almost negligible. In an anion-exchange method using 0.1 M HF carrier solution, tantalum and boron in the sample solution were first adsorbed on a strongly basic anion-exchange resin. Next, boron was eluted from the resin with 5 M HCl, whereas tantalum was retained strongly adsorbed. The eluted boron was introduced directly into the ICP-MS system for quantitative analysis at m/z 10 and 11. Because of the long elution time of boron, the transient signal was integrated in the time range 70-300 s on the chromatogram. Although the elution of boron in the time range was ca. 40% of total boron in the sample solution injected, the determination limits (10sigma) obtained by the present method were 30, 25, 15 and 13 ng g(-1) for tantalum metal, tantalum(v) oxide, tantalum pentachloride and tantalum pentaethoxide, respectively. The method was applied to the determination of boron in commercially available high-purity tantalum materials and it was found that the concentrations of boron were in the ng g(-1)-microg g(-1) range. PMID:12173652

  12. Polysialylated N-Glycans Identified in Human Serum Through Combined Developments in Sample Preparation, Separations and Electrospray ionization-mass spectrometry

    SciTech Connect

    Kronewitter, Scott R.; Marginean, Ioan; Cox, Jonathan T.; Zhao, Rui; Hagler, Clay D.; Shukla, Anil K.; Carlson, Timothy S.; Adkins, Joshua N.; Camp, David G.; Moore, Ronald J.; Rodland, Karin D.; Smith, Richard D.

    2014-09-02

    The N-glycan diversity of human serum glycoproteins, i.e. the human blood serum N-glycome, is complex due to the range of glycan structures potentially synthesizable by human glycosylation enzymes. The reported glycome, however, is limited by methods of sample preparation, available analytical platforms, e.g., based upon electrospray ionization-mass spectrometry (ESI-MS), and software tools for data analysis. In this report, several improvements have been implemented in sample preparation and analysis to extend ESI-MS glycan characterization and to provide an improved view of glycan diversity. Sample preparation improvements include acidified, microwave-accelerated, PNGase F N-glycan release, and sodium borohydride reduction were optimized to improve quantitative yields and conserve the number of glycoforms detected. Two-stage desalting (during solid phase extraction and on the analytical column) increased the sensitivity by reducing analyte signal division between multiple reducing-end-forms or cation adducts. On-line separations were improved by using extended length graphitized carbon columns and adding TFA as an acid modifier to a formic acid/reversed phase gradient which provides additional resolving power and significantly improved desorption of both large and heavily sialylated glycans. To improve MS sensitivity and provide gentler ionization conditions at the source-MS interface, subambient pressure ionization with nanoelectrospray (SPIN) has been utilized. When method improvements are combined together with the Glycomics Quintavariate Informed Quantification (GlyQ-IQ) recently described1 these technologies demonstrate the ability to significantly extend glycan detection sensitivity and provide expanded glycan coverage. We demonstrate application of these advances in the context of the human serum glycome, and for which our initial observations include detection of a new class of heavily sialylated N-glycans, including polysialylated N-glycans.

  13. A recoil detector for the measurement of antiproton-proton elastic scattering at angles close to 90°

    NASA Astrophysics Data System (ADS)

    Hu, Q.; Bechstedt, U.; Gillitzer, A.; Grzonka, D.; Khoukaz, A.; Klehr, F.; Lehrach, A.; Prasuhn, D.; Ritman, J.; Sefzick, T.; Stockmanns, T.; Täschner, A.; Wuestner, P.; Xu, H.

    2014-10-01

    The design and construction of a recoil detector for the measurement of recoil protons of antiproton-proton elastic scattering at scattering angles close to are described. The performance of the recoil detector has been tested in the laboratory with radioactive sources and at COSY with proton beams by measuring proton-proton elastic scattering. The results of laboratory tests and commissioning with beam are presented. Excellent energy resolution and proper working performance of the recoil detector validate the conceptual design of the KOALA experiment at HESR to provide the cross section data needed to achieve a precise luminosity determination at the PANDA experiment.

  14. Measurement of nuclear recoil quenching factors in CaWO 4

    NASA Astrophysics Data System (ADS)

    Jagemann, Th.; Feilitzsch, F. v.; Hagn, H.; Jochum, J.; Potzel, W.; Rau, W.; Stark, M.; Westphal, W.

    2006-11-01

    The CRESST experiment, aiming at the direct detection of WIMPs via nuclear recoils, is currently using scintillating CaWO4 crystals. The WIMP-nucleus cross section for elastic scattering as well as the scintillation efficiency differ considerably for recoils from Ca, W and O in these crystals. Therefore a discriminating detector calibration is essential in order to improve WIMP parameter claims. At the tandem accelerator of the Maier-Leibnitz-Laboratory (MLL) in Garching, Germany, a neutron scattering facility is operated for the determination of the individual quenching factors (QF) in the bulk of a CaWO4 crystal to better understand the detector response to neutron background and a possible WIMP signal. First measurements at room temperature reveal QF(O) = 7.8 ± 0.3% (recoil energy 1.0-2.2 MeV), QF(Ca) = 6.3 ± 1.6% (recoil energy 0.4-1 MeV), QF(W) < 3.0% (2σ, recoil energy 0.1 MeV).

  15. Treatment of solid tumors by interstitial release of recoiling short-lived alpha emitters

    NASA Astrophysics Data System (ADS)

    Arazi, L.; Cooks, T.; Schmidt, M.; Keisari, Y.; Kelson, I.

    2007-08-01

    A new method utilizing alpha particles to treat solid tumors is presented. Tumors are treated with interstitial radioactive sources which continually release short-lived alpha emitting atoms from their surface. The atoms disperse inside the tumor, delivering a high dose through their alpha decays. We implement this scheme using thin wire sources impregnated with 224Ra, which release by recoil 220Rn, 216Po and 212Pb atoms. This work aims to demonstrate the feasibility of our method by measuring the activity patterns of the released radionuclides in experimental tumors. Sources carrying 224Ra activities in the range 10-130 kBq were used in experiments on murine squamous cell carcinoma tumors. These included gamma spectroscopy of the dissected tumors and major organs, Fuji-plate autoradiography of histological tumor sections and tissue damage detection by Hematoxylin-Eosin staining. The measurements focused on 212Pb and 212Bi. The 220Rn/216Po distribution was treated theoretically using a simple diffusion model. A simplified scheme was used to convert measured 212Pb activities to absorbed dose estimates. Both physical and histological measurements confirmed the formation of a 5-7 mm diameter necrotic region receiving a therapeutic alpha-particle dose around the source. The necrotic regions shape closely corresponded to the measured activity patterns. 212Pb was found to leave the tumor through the blood at a rate which decreased with tumor mass. Our results suggest that the proposed method, termed DART (diffusing alpha-emitters radiation therapy), may potentially be useful for the treatment of human patients.

  16. Azimuthal asymmetry of recoil electrons in neutrino-electron elastic scattering as signature of neutrino nature

    NASA Astrophysics Data System (ADS)

    Sobków, W.; Błaut, A.

    2016-05-01

    In this paper, we analyze the theoretically possible scenario beyond the standard model in order to show how the presence of the exotic scalar, tensor, {V}+{A} weak interactions in addition to the standard vector-axial ({V}-{A}) ones may help to distinguish the Dirac from Majorana neutrinos in the elastic scattering of an (anti)neutrino beam off the unpolarized electrons in the relativistic limit. We assume that the incoming (anti)neutrino beam comes from the polarized muon decay at rest and is the left-right chiral superposition with assigned direction of the transversal spin polarization with respect to the production plane. Our analysis is carried out for the flavour (current) neutrino eigenstates. It means that the transverse neutrino polarization estimates are the same both for the Dirac and Majorana cases. We display that the azimuthal asymmetry in the angular distribution of recoil electrons is generated by the interference terms between the standard and exotic couplings, which are proportional to the transversal (anti)neutrino spin polarization and independent of the neutrino mass. This asymmetry for the Majorana neutrinos is larger than for the Dirac ones. We also indicate the possibility of utilizing the azimuthal asymmetry measurements to search for the new CP-violating phases. Our study is based on the assumption that the possible detector (running for 1 year) has the shape of a flat circular ring, while the intense neutrino source is located in the centre of the ring and polarized perpendicularly to the ring. In addition, the large low-threshold, real-time detector is able to measure with a high resolution both the polar angle and the azimuthal angle of outgoing electron momentum. Our analysis is model-independent and consistent with the current upper limits on the non-standard couplings.

  17. B → Dℓν form factors at nonzero recoil and |Vcb| from 2+1-flavor lattice QCD

    DOE PAGESBeta

    Bailey, Jon A.

    2015-08-10

    We present the first unquenched lattice-QCD calculation of the hadronic form factors for the exclusive decay B¯→Dℓν¯ at nonzero recoil. We carry out numerical simulations on 14 ensembles of gauge-field configurations generated with 2+1 flavors of asqtad-improved staggered sea quarks. The ensembles encompass a wide range of lattice spacings (approximately 0.045 to 0.12 fm) and ratios of light (up and down) to strange sea-quark masses ranging from 0.05 to 0.4. For the b and c valence quarks we use improved Wilson fermions with the Fermilab interpretation, while for the light valence quarks we use asqtad-improved staggered fermions. We extrapolate ourmore » results to the physical point using rooted staggered heavy-light meson chiral perturbation theory. We then parametrize the form factors and extend them to the full kinematic range using model-independent functions based on analyticity and unitarity. We present our final results for f+(q2) and f0(q2), including statistical and systematic errors, as coefficients of a series in the variable z and the covariance matrix between these coefficients. We then fit the lattice form-factor data jointly with the experimentally measured differential decay rate from BABAR to determine the CKM matrix element, |Vcb|=(39.6 ± 1.7QCD+exp ± 0.2QED) × 10–3. As a byproduct of the joint fit we obtain the form factors with improved precision at large recoil. In conclusion, we use them to update our calculation of the ratio R(D) in the Standard Model, which yields R(D)=0.299(11).« less

  18. Recoiling black holes: prospects for detection and implications of spin alignment

    NASA Astrophysics Data System (ADS)

    Blecha, Laura; Sijacki, Debora; Kelley, Luke Zoltan; Torrey, Paul; Vogelsberger, Mark; Nelson, Dylan; Springel, Volker; Snyder, Gregory; Hernquist, Lars

    2016-02-01

    Supermassive black hole (BH) mergers produce powerful gravitational wave emission. Asymmetry in this emission imparts a recoil kick to the merged BH, which can eject the BH from its host galaxy altogether. Recoiling BHs could be observed as offset active galactic nuclei (AGN). Several candidates have been identified, but systematic searches have been hampered by large uncertainties regarding their observability. By extracting merging BHs and host galaxy properties from the Illustris cosmological simulations, we have developed a comprehensive model for recoiling AGN. Here, for the first time, we model the effects of BH spin alignment and recoil dynamics based on the gas richness of host galaxies. We predict that if BH spins are not highly aligned, seeing-limited observations could resolve offset AGN, making them promising targets for all-sky surveys. For randomly oriented spins, ≲ 10 spatially offset AGN may be detectable in Hubble Space Telescope-Cosmological Evolution Survey, and >103 could be found with the Panoramic Survey Telescope & Rapid Response System (Pan-STARRS), the Large Synoptic Survey Telescope (LSST), Euclid, and the Wide-Field Infrared Survey Telescope (WFIRST). Nearly a thousand velocity offset AGN are predicted within the Sloan Digital Sky Survey (SDSS) footprint; the rarity of large broad-line offsets among SDSS quasars is likely due in part to selection effects but suggests that spin alignment plays a role in suppressing recoils. None the less, in our most physically motivated model where alignment occurs only in gas-rich mergers, hundreds of offset AGN should be found in all-sky surveys. Our findings strongly motivate a dedicated search for recoiling AGN.

  19. Gastrointestinal cell proliferation and crypt fission are separate but complementary means of increasing tissue mass following infusion of epidermal growth factor in rats

    PubMed Central

    Berlanga-Acosta, J; Playford, R; Mandir, N; Goodlad, R

    2001-01-01

    BACKGROUND AND AIMS—Epidermal growth factor (EGF) is a potent mitogen for the gastrointestinal tract and also influences the number of new crypts formed by crypt fission. The time course of these events and possible linkage between these two complementary mechanisms is however poorly understood. We therefore examined the temporal relationship of proliferation and fission in rats treated with EGF.
METHODS—Osmotic minipumps were implanted subcutaneously into male Wistar rats to infuse EGF continuously (60 µg/rat/day) for periods of 1-14 days. Proliferation and crypt branching were quantified following vincristine induced metaphase arrest and morphometric assessment of microdissected tissue.
RESULTS—In the small intestine, EGF significantly increased epithelial cell proliferation and crypt and villus area after 24 hours of EGF, although maximal effects were only reached following six days of infusion. EGF also resulted in an approximate 30% reduction in crypt fission in the small bowel. In the colon, EGF caused a twofold increase in epithelial cell proliferation one day after infusion, from 15.3 (2.3) to 29.6 (3.5) metaphases per crypt (p<0.01). Maximal effects were seen in rats receiving EGF for seven days. For all time points, colonic crypt size increased in response to EGF. The amount of branching increased following one day of infusion with EGF (from 15.3 (1.9) to 32.4 (5.5)%; p<0.001) but was significantly lower (approximately 25% of control values) following longer periods of infusion. Crypt fission did not correlate with crypt area.
CONCLUSION—EGF has profound effects on cell proliferation and also altered crypt fission, with its actions on crypt fission most pronounced in the colon where it first increased and then decreased fission. EGF can thus be a potent stimulus for crypt fission during short term infusion and may reduce the number of branched crypts present in a resting or quiescent stage. Growth factors can alter cell mass by two

  20. Rapid assessment of human amylin aggregation and its inhibition by copper(II) ions by laser ablation electrospray ionization mass spectrometry with ion mobility separation.

    PubMed

    Li, Hang; Ha, Emmeline; Donaldson, Robert P; Jeremic, Aleksandar M; Vertes, Akos

    2015-10-01

    Native electrospray ionization (ESI) mass spectrometry (MS) is often used to monitor noncovalent complex formation between peptides and ligands. The relatively low throughput of this technique, however, is not compatible with extensive screening. Laser ablation electrospray ionization (LAESI) MS combined with ion mobility separation (IMS) can analyze complex formation and provide conformation information within a matter of seconds. Islet amyloid polypeptide (IAPP) or amylin, a 37-amino acid residue peptide, is produced in pancreatic beta-cells through proteolytic cleavage of its prohormone. Both amylin and its precursor can aggregate and produce toxic oligomers and fibrils leading to cell death in the pancreas that can eventually contribute to the development of type 2 diabetes mellitus. The inhibitory effect of the copper(II) ion on amylin aggregation has been recently discovered, but details of the interaction remain unknown. Finding other more physiologically tolerated approaches requires large scale screening of potential inhibitors. Here, we demonstrate that LAESI-IMS-MS can reveal the binding stoichiometry, copper oxidation state, and the dissociation constant of human amylin-copper(II) complex. The conformations of hIAPP in the presence of copper(II) ions were also analyzed by IMS, and preferential association between the β-hairpin amylin monomer and the metal ion was found. The copper(II) ion exhibited strong association with the -HSSNN- residues of the amylin. In the absence of copper(II), amylin dimers were detected with collision cross sections consistent with monomers of β-hairpin conformation. When copper(II) was present in the solution, no dimers were detected. Thus, the copper(II) ions disrupt the association pathway to the formation of β-sheet rich amylin fibrils. Using LAESI-IMS-MS for the assessment of amylin-copper(II) interactions demonstrates the utility of this technique for the high-throughput screening of potential inhibitors of amylin

  1. Rapid Assessment of Human Amylin Aggregation and Its Inhibition by Copper(II) Ions by Laser Ablation Electrospray Ionization Mass Spectrometry with Ion Mobility Separation

    PubMed Central

    Donaldson, Robert P.; Jeremic, Aleksandar M.; Vertes, Akos

    2015-01-01

    Native electrospray ionization (ESI) mass spectrometry (MS) is often used to monitor noncovalent complex formation between peptides and ligands. The relatively low throughput of this technique, however, is not compatible with extensive screening. Laser ablation electrospray ionization (LAESI) MS combined with ion mobility separation (IMS) can analyze complex formation and provide conformation information within a matter of seconds. Islet amyloid polypeptide (IAPP) or amylin, a 37-amino acid residue peptide, is produced in pancreatic beta-cells through proteolytic cleavage of its prohormone. Both amylin and its precursor can aggregate and produce toxic oligomers and fibrils leading to cell death in the pancreas that can eventually contribute to the development of type 2 diabetes mellitus. The inhibitory effect of the copper(II) ion on amylin aggregation has been recently discovered, but details of the interaction remain unknown. Finding other more physiologically tolerated approaches requires large scale screening of potential inhibitors. Here, we demonstrate that LAESI-IMS-MS can reveal the binding stoichiometry, copper oxidation state, and the dissociation constant of human amylin–copper(II) complex. The conformations of hIAPP in the presence of copper(II) ions were also analyzed by IMS, and preferential association between the β-hairpin amylin monomer and the metal ion was found. The copper(II) ion exhibited strong association with the –HSSNN– residues of the amylin. In the absence of copper(II), amylin dimers were detected with collision cross sections consistent with monomers of β-hairpin conformation. When copper(II) was present in the solution, no dimers were detected. Thus, the copper(II) ions disrupt the association pathway to the formation of β-sheet rich amylin fibrils. Using LAESI-IMS-MS for the assessment of amylin–copper(II) interactions demonstrates the utility of this technique for the high-throughput screening of potential inhibitors of

  2. Radiation Recoil Effects on the Dynamical Evolution of Asteroids

    NASA Astrophysics Data System (ADS)

    Cotto-Figueroa, Desiree

    The Yarkovsky effect is a radiation recoil force that results in a semimajor axis drift in the orbit that can cause Main Belt asteroids to be delivered to powerful resonances from which they could be transported to Earth-crossing orbits. This force depends on the spin state of the object, which is modified by the YORP effect, a variation of the Yarkovsky effect that results in a torque that changes the spin rate and the obliquity. Extensive analyses of the basic behavior of the YORP effect have been previously conducted in the context of the classical spin state evolution of rigid bodies (YORP cycle). However, the YORP effect has an extreme sensitivity to the topography of the asteroids and a minor change in the shape of an aggregate asteroid can stochastically change the YORP torques. Here we present the results of the first simulations that self-consistently model the YORP effect on the spin states of dynamically evolving aggregates. For these simulations we have developed several algorithms and combined them with two codes, TACO and pkdgrav. TACO is a thermophysical asteroid code that models the surface of an asteroid using a triangular facet representation and which can compute the YORP torques. The code pkdgrav is a cosmological N-body tree code modified to simulate the dynamical evolution of asteroids represented as aggregates of spheres using gravity and collisions. The continuous changes in the shape of an aggregate result in a different evolution of the YORP torques and therefore aggregates do not evolve through the YORP cycle as a rigid body would. Instead of having a spin evolution ruled by long periods of rotational acceleration and deceleration as predicted by the classical YORP cycle, the YORP effect is self-limiting and stochastic on aggregate asteroids. We provide a statistical description of the spin state evolution which lays out the foundation for new simulations of a coupled Yarkovsky/YORP evolution. Both self-limiting YORP and to a lesser

  3. B →π ℓν at zero recoil from lattice QCD with physical u /d quarks

    NASA Astrophysics Data System (ADS)

    Colquhoun, B.; Dowdall, R. J.; Koponen, J.; Davies, C. T. H.; Lepage, G. P.

    2016-02-01

    The exclusive semileptonic decay B →π ℓν is a key process for the determination of the Cabibbo-Kobayashi-Maskawa matrix element Vu b from the comparison of experimental rates as a function of q2 with theoretically determined form factors. The sensitivity of the form factors to the u /d quark mass has meant significant systematic uncertainties in lattice QCD calculations at unphysically heavy pion masses. Here, we give the first lattice QCD calculations of this process for u /d quark masses going down to their physical values, calculating the f0 form factor at zero recoil to 3%. We are able to resolve a long-standing controversy by showing that the soft-pion theorem result f0(qmax2)=fB/fπ does hold as mπ→0 . We use the highly improved staggered quark formalism for the light quarks and show that staggered chiral perturbation theory for the mπ dependence is almost identical to continuum chiral perturbation theory for f0, fB, and fπ. We also give results for other processes such as Bs→K ℓν .

  4. Discrimination of nuclear and electronic recoil events using plasma effect in germanium detectors

    NASA Astrophysics Data System (ADS)

    Wei, W.-Z.; Liu, J.; Mei, D.-M.

    2016-07-01

    We report a new method of using the plasma time difference, which results from the plasma effect, between the nuclear and electronic recoil events in high-purity germanium detectors to distinguish these two types of events in the search for rare physics processes. The physics mechanism of the plasma effect is discussed in detail. A numerical model is developed to calculate the plasma time for nuclear and electronic recoils at various energies in germanium detectors. It can be shown that under certain conditions the plasma time difference is large enough to be observable. The experimental aspects in realizing such a discrimination in germanium detectors is discussed.

  5. Development of the RAON Recoil Spectrometer (KOBRA) and Its Applications for Nuclear Astrophysics

    NASA Astrophysics Data System (ADS)

    Moon, Jun Young; Park, Junesic; Cheoul Yun, Chong; Kwon, Young Kwan; Komatsubara, Tetsuro; Hashimoto, Takashi; Tshoo, Kyoungho; Lee, Kwangbok; Jung, In-IL; Kim, Yong Hak; Kim, Yong-Kyun

    KOBRA (KOrea Broad acceptance Recoil spectrometer and Apparatus), a new generation recoil spectrometer, has been designed at the Korean heavy-ion accelerator facility, so called RAON. It will allow many nuclear scientists to explore so-far hard but very interesting questions relevant to low-energy nuclear physics. Especially, in nuclear astrophysics where the unstable, short-lived nuclei are usually involved and the high background rejection power is required, its high performance will come into significantly important role. As a particular case to see its capability, in this article, calculational results of 12C(α, γ)16O reaction which was studied with the COSY-INFINITY is presented.

  6. Evaluation of Enhanced Comprehensive 2-D Gas Chromatography-Time-Of-Flight Mass Spectrometry for the Separation of Recalcitrant Polychlorinated Biphenyl Isomers

    EPA Science Inventory

    The separation of some recalcitrant polychlorinated biphenyl (PCB) isomers in extracts from environmental compartments has been a daunting task for environmental chemists. Summed quantitation values for coeluting PCB isomers are often reported. This composite data obscures the ac...

  7. Ultracapacitor separator

    DOEpatents

    Wei, Chang; Jerabek, Elihu Calvin; LeBlanc, Jr., Oliver Harris

    2001-03-06

    An ultracapacitor includes two solid, nonporous current collectors, two porous electrodes separating the collectors, a porous separator between the electrodes and an electrolyte occupying the pores in the electrodes and separator. The electrolyte is a polar aprotic organic solvent and a salt. The porous separator comprises a wet laid cellulosic material.

  8. Topographical and Chemical Imaging of a Phase Separated Polymer Using a Combined Atomic Force Microscopy/Infrared Spectroscopy/Mass Spectrometry Platform

    DOE PAGESBeta

    Tai, Tamin; Karácsony, Orsolya; Bocharova, Vera; Van Berkel, Gary J.; Kertesz, Vilmos

    2016-02-18

    This article describes how the use of a hybrid atomic force microscopy/infrared spectroscopy/mass spectrometry imaging platform was demonstrated for the acquisition and correlation of nanoscale sample surface topography and chemical images based on infrared spectroscopy and mass spectrometry.

  9. Separation of plutonium and neptunium species by capillary electrophoresis-inductively coupled plasma-mass spectrometry and application to natural groundwater samples.

    PubMed

    Kuczewski, Bernhard; Marquardt, Christian M; Seibert, Alice; Geckeis, Horst; Kratz, Jens Volker; Trautmann, Norbert

    2003-12-15

    Capillary electrophoresis (CE) was coupled to ICPMS in order to combine the good performance of this separation technique with the high sensitivity of the ICPMS for the analysis of plutonium and neptunium oxidation states. The combination of a fused-silica capillary with a MicroMist AR 30-I-FM02 nebulizer and a Cinnabar small-volume cyclonic spray chamber yielded the best separation results. With this setup, it was possible to separate a model element mixture containing neptunium (NpO2(+)), uranium (UO2(2+)), lanthanum (La3+), and thorium (Th4+) in 1 M acetic acid. The same conditions were also suitable for the separation of various oxidation states of plutonium and neptunium in different aqueous samples. All separations were obtained within less than 15 min. A detection limit of 50 ppb identical with 2 x 10(-7) M (3-fold standard deviation of a blank) was achieved. To prove the negligible disturbance of the plutonium and neptunium redox equilibria during the CE separations, plutonium and neptunium speciation by CE-ICPMS in acidic solutions was compared with the results of UV/visible absorption spectroscopy and was found to be in good agreement. The CE-ICPMS system was also applied to study the reduction of Pu(VI) in a humic acid-containing groundwater at different pH values. PMID:14670034

  10. Complex decay patterns in atomic core photoionization disentangled by ion-recoil measurements

    SciTech Connect

    Guillemin, Renaud; Bomme, Cedric; Marin, Thierry; Journel, Loic; Marchenko, Tatiana; Kushawaha, Rajesh K.; Piancastelli, Maria Novella; Simon, Marc; Trcera, Nicolas

    2011-12-15

    Following core 1s ionization and resonant excitation of argon atoms, we measure the recoil energy of the ions due to momentum conservation during the emission of Auger electrons. We show that such ion momentum spectroscopy can be used to disentangle to some degree complex decay patterns, involving both radiative and nonradiative decays.

  11. Microfabrication, separations, and detection by mass spectrometry on ultrathin-layer chromatography plates prepared via the low-pressure chemical vapor deposition of silicon nitride onto carbon nanotube templates.

    PubMed

    Kanyal, Supriya S; Häbe, Tim T; Cushman, Cody V; Dhunna, Manan; Roychowdhury, Tuhin; Farnsworth, Paul B; Morlock, Gertrud E; Linford, Matthew R

    2015-07-24

    Microfabrication of ultrathin-layer chromatography (UTLC) plates via conformal deposition of silicon nitride by low-pressure chemical vapor deposition onto patterned carbon nanotube (CNT) scaffolds was demonstrated. After removal of the CNTs and hydroxylation, the resulting UTLC phase showed no expansion or distortion of their microfeatures and the absence/reduction of remaining nitrogenic species. Developing time of a mixture of lipophilic dyes on this UTLC plates was 86% shorter than on high-performance thin-layer chromatography (HPTLC) plates. A water-soluble food dye mixture was also separated resulting in low band broadening and reduced developing time compared to HPTLC. For the latter example, mobile phase optimization on a single UTLC plate consisted of 14 developments with different mobile phases, each preceded by a plate prewashing step. The same plate was again reused for additional 11 separations under varying conditions resulting in a development procedure with a mean separation efficiency of 233,000theoretical plates/m and a reduced mobile phase consumption of only 400μL. This repeated use proved the physical robustness of the ultrathin layer and its resistance to damage. The layer was highly suited for hyphenation to ambient mass spectrometry, including desorption electrospray ionization (DESI) mass spectrometry imaging and direct analysis in real time (DART) mass spectrometry. PMID:26065571

  12. Implementation of a design of experiments to study the influence of the background electrolyte on separation and detection in non-aqueous capillary electrophoresis-mass spectrometry.

    PubMed

    Posch, Tjorben Nils; Müller, Alexander; Schulz, Wolfgang; Pütz, Michael; Huhn, Carolin

    2012-02-01

    Non-aqueous capillary electrophoresis (NACE) background electrolytes are most often composed of a mixture of methanol and acetonitrile (ACN) with soluble ammonium salts added as electrolyte. In this study on NACE-MS, we used a mixture of glacial acetic acid and ACN giving rise to an acidic background electrolyte (BGE) with a very low dielectric constant. Impressive changes in selectivity and resolution were observed for structurally closely related indole alkaloids including diastereomers upon addition of ammonium formate as electrolyte and upon variation of the solvent ratio. In order to obtain best separation and MS detection conditions and to reveal the influence of the parameters of the BGE on separation and detection and vice versa of the MS parameters on separation, an optimization strategy was employed using a design of experiments in a central composite design with response surface methodology. It was proven that at high electroosmotic flow conditions capillary electrophoretic separations and thus optimization can be realized without interference from the coupling to an MS system. Several significantly interacting parameters were revealed, which are not accessible with classical univariate optimization approaches. With this optimization, alkaloid mixtures from a plant extract of Mitragyna speciosa, containing a large number of diastereomeric compounds were successfully separated. PMID:22451051

  13. Determination of 90Sr / 238U ratio by double isotope dilution inductively coupled plasma mass spectrometer with multiple collection in spent nuclear fuel samples with in situ 90Sr / 90Zr separation in a collision-reaction cell

    NASA Astrophysics Data System (ADS)

    Isnard, H.; Aubert, M.; Blanchet, P.; Brennetot, R.; Chartier, F.; Geertsen, V.; Manuguerra, F.

    2006-02-01

    Strontium-90 is one of the most important fission products generated in nuclear industry. In the research field concerning nuclear waste disposal in deep geological environment, it is necessary to quantify accurately and precisely its concentration (or the 90Sr / 238U atomic ratio) in irradiated fuels. To obtain accurate analysis of radioactive 90Sr, mass spectrometry associated with isotope dilution is the most appropriated method. But, in nuclear fuel samples the interference with 90Zr must be previously eliminated. An inductively coupled plasma mass spectrometer with multiple collection, equipped with an hexapole collision cell, has been used to eliminate the 90Sr / 90Zr interference by addition of oxygen in the collision cell as a reactant gas. Zr + ions are converted into ZrO +, whereas Sr + ions are not reactive. A mixed solution, prepared from a solution of enriched 84Sr and a solution of enriched 235U was then used to quantify the 90Sr / 238U ratio in spent fuel sample solutions using the double isotope dilution method. This paper shows the results, the reproducibility and the uncertainties that can be obtained with this method to quantify the 90Sr / 238U atomic ratio in an UOX (uranium oxide) and a MOX (mixed oxide) spent fuel samples using the collision cell of an inductively coupled plasma mass spectrometer with multiple collection to perform the 90Sr / 90Zr separation. A comparison with the results obtained by inductively coupled plasma mass spectrometer with multiple collection after a chemical separation of strontium from zirconium using a Sr spec resin (Eichrom) has been performed. Finally, to validate the analytical procedure developed, measurements of the same samples have been performed by thermal ionization mass spectrometry, used as an independent technique, after chemical separation of Sr.

  14. Modeling ionization and recombination from low energy nuclear recoils in liquid argon

    SciTech Connect

    Foxe, Michael P.; Hagmann, Chris; Jovanovic, Igor; Bernstein, A.; Joshi, T.; Kazkaz, K.; Mozin, Vladimir V.; Pereverzev, S. V.; Sangiorgio, Samuele; Sorensen, Peter F.

    2015-09-01

    Coherent neutrino-nucleus scattering (CNNS) is an as-yet undetected, flavor-independent neutrino interaction predicted by the Standard Model. CNNS is a flavor-blind interaction, which offers potential benefits for its use in nonproliferation (nuclear reactor monitoring) and astrophysics (supernova and solar neutrinos) applications. One challenge with detecting CNNS is the low energy deposition associated with a typical CNNS nuclear recoil. In addition, nuclear recoils are predicted to result in lower ionization yields than those produced by electron recoils of the same energy. This ratio of nuclear- and electron-induced ionization, known as the nuclear quenching factor, is unknown at energies typical for CNNS interactions in liquid xenon (LXe) and liquid argon (LAr), detector media being considered for CNNS detection. While there have been recent measurements [1] of the ionization yield from nuclear recoils in LAr, there is no universal model for nuclear quenching and ionization yield. For this reason, a Monte Carlo simulation has been developed to predict the ionization yield at sub-10 keV energies. The local ionization yield of a recoiling atom in the medium is calculated first. The ejected electrons are subsequently tracked in the electric field resulting from both the local electric charges and the externally applied drift field. The dependence of the ionization yield on the drift electric field is obtained by combining the calculated ionization yield for the initial collision cascade with the electron escape probability. An updated estimate of the CNNS signal expected in a LAr detector operated near a nuclear power reactor is presented.

  15. A gas chromatograph/mass spectrometry method for determining isotopic distributions in organic compounds used in the chemical approach to stable isotope separation

    SciTech Connect

    Martinez, A.M.; Spall, W.D.; Smith, B.F.

    1990-01-01

    A variety of gas chromatograph/mass spectrometry (GC/MS) methods have been developed to resolve benzene, benzophenone, anthracene, fluorenone, and their respective stable isotope analogs from other components by gas chromatography. The ratio of stable isotope-labeled material to natural isotopic abundance compounds is determined from the mass spectra averaged across the chromatographic peak. Both total ion and selective ion chromatographic approaches were used for relative data and comparison. 9 refs., 11 tabs.

  16. The XENON100 Dark Matter Experiment: Design, Construction, Calibration and 2010 Search Results with Improved Measurement of the Scintillation Response of Liquid Xenon to Low-Energy Nuclear Recoils

    NASA Astrophysics Data System (ADS)

    Plante, Guillaume

    An impressive array of astrophysical observations suggest that 83% of the matter in the universe is in a form of non-luminous, cold, collisionless, non-baryonic dark matter. Several extensions of the Standard Model of particle physics aimed at solving the hierarchy problem predict stable weakly interacting massive particles (WIMPs) that could naturally have the right cosmological relic abundance today to compose most of the dark matter if their interactions with normal matter are on the order of a weak scale cross section. These candidates also have the added benefit that their properties and interaction rates can be computed in a well defined particle physics model. A considerable experimental effort is currently under way to uncover the nature of dark matter. One method of detecting WIMP dark matter is to look for its interactions in terrestrial detectors where it is expected to scatter off nuclei. In 2007, the XENON10 experiment took the lead over the most sensitive direct detection dark matter search in operation, the CDMS II experiment, by probing spin-independent WIMP-nucleon interaction cross sections down to sigmachi N ˜ 5 x 10-44 cm 2 at 30 GeV/c2. Liquefied noble gas detectors are now among the technologies at the forefront of direct detection experiments. Liquid xenon (LXe), in particular, is a well suited target for WIMP direct detection. It is easily scalable to larger target masses, allows discrimination between nuclear recoils and electronic recoils, and has an excellent stopping power to shield against external backgrounds. A particle losing energy in LXe creates both ionization electrons and scintillation light. In a dual-phase LXe time projection chamber (TPC) the ionization electrons are drifted and extracted into the gas phase where they are accelerated to amplify the charge signal into a proportional scintillation signal. These two signals allow the three-dimensional localization of events with millimeter precision and the ability to

  17. This-layer chromatography/electrospray ionization triple-quadrupole linear ion trap mass spectrometry system: analysis of rhodamine dyes separated on reversed-phase C8 plates

    SciTech Connect

    Ford, Michael J; Kertesz, Vilmos; Van Berkel, Gary J

    2005-01-01

    The direct analysis of separated rhodamine dyes on reversed-phase C{sub 8} thin-layer chromatography plates using a surface sampling/electrospray emitter probe coupled with a triple-quadrupole linear ion trap mass spectrometer is presented. This report represents continuing work to advance the performance metrics and utility of this basic surface sampling electrospray mass spectrometry system for the analysis of thin-layer chromatography plates. Experimental results examining the role of sampling probe spray end configuration on liquid aspiration rate and gas-phase ion signal generated are discussed. The detection figures-of-merit afforded by full-scan, automated product ion and selected reaction monitoring modes of operation were examined. The effect of different eluting solvents on mass spectrum signal levels with the reversed-phase C{sub 8} plate was investigated. The combined effect of eluting solvent flow-rate and development lane surface scan rate on preservation of chromatographic resolution was also studied. Analysis of chromatographically separated red pen ink extracts from eight different pens using selected reaction monitoring demonstrated the potential of this surface sampling electrospray mass spectrometry system for targeted compound analysis with real samples.

  18. Numerical Simulations of 1-D Two-Phase Flow with Non-Zero Mass Fluxes: Application to Phase Separation at 9° N (EPR) and the Main Endeavour Vent Field (JDF)

    NASA Astrophysics Data System (ADS)

    Lewis, K.; Lowell, R. P.

    2004-12-01

    Numerical simulations of vertical one-dimensional two-phase flow with non-zero mass fluxes can help to enumerate and describe the different parameter space regimes at which phase separation can occur in submarine hydrothermal systems. Our simulations suggest that there are at least two such quasi-steady state regimes, corresponding to low and high mass fluxes imposed at the bottom of the system. For relatively low mass fluxes (10-5 - 10-4 kg/m2-s), a low salinity vapor-rich region forms near the top of the system, and high-salinity brine flows downward, raising the salinity in the lower half of the system. For high mass fluxes (&\\sim 10^{-3} kg/m^{2}-s), both vapor and brine flow upward, with the vapor moving more quickly than the brine. In this case, phase separation results in higher salinities near the top of the system, corresponding to a mixture of brine and vapor, and salinities approaching that of normal seawater lower in the system. Bulk surface salinities in the high-flux regime are qualitatively consistent with vent fluid salinities at hydrothermal systems such as 9\\deg$N on the East Pacific Rise and some of the vents of the Main Endeavour Field on the Juan de Fuca Ridge. Our future work will further test this preliminary analysis.

  19. Complete and incomplete fusion reactions in the {sup 16}O+{sup 169}Tm system: Excitation functions and recoil range distributions

    SciTech Connect

    Sharma, Manoj Kumar; Unnati,; Sharma, B.K.; Singh, B.P.; Prasad, R.; Bhardwaj, H.D.; Kumar, Rakesh; Golda, K.S.

    2004-10-01

    With the view to study complete and incomplete fusion in heavy ion induced reactions, experiments have been carried out for measuring excitation functions for several reactions in the system {sup 16}O+{sup 169}Tm at energies near the Coulomb barrier to well above it, using an activation technique. The measured excitation functions have been compared with those calculated theoretically using three different computer codes viz., ALICE-91, CASCADE and PACE2. The enhancement of experimentally measured cross sections for alpha emission channels over their theoretical prediction has been attributed to the fact that these residues are formed not only by complete fusion but also through incomplete fusion. In order to separate out the relative contributions of complete and incomplete fusion, the recoil range distributions of eight residues produced in the interaction of {sup 16}O with {sup 169}Tm at {approx_equal}87 MeV have been measured. The recoil range distributions indicate significant contributions from incomplete fusion at {approx_equal}87 MeV for some of the channels.

  20. Separated flow

    NASA Technical Reports Server (NTRS)

    Sellers, W. L., III; Dunham, R. E., Jr.; Goodman, W. L.; Howard, F. G.; Margason, R. J.; Rudy, D. H.; Rumsey, C. L.; Stough, H. P., III; Thomas, J. L.

    1986-01-01

    A brief overview of flow separation phenomena is provided. Langley has many active research programs in flow separation related areas. Three cases are presented which describe specific examples of flow separation research. In each example, a description of the fundamental fluid physics and the complexity of the flow field is presented along with a method of either reducing or controlling the extent of separation. The following examples are discussed: flow over a smooth surface with an adverse pressure gradient; flow over a surface with a geometric discontinuity; and flow with shock-boundary layer interactions. These results will show that improvements are being made in the understanding of flow separation and its control.

  1. First detection and energy measurement of recoil ions following beta decay in a Penning trap with the WITCH experiment

    NASA Astrophysics Data System (ADS)

    Beck, M.; Coeck, S.; Kozlov, V. Yu.; Breitenfeldt, M.; Delahaye, P.; Friedag, P.; Glück, F.; Herbane, M.; Herlert, A.; Kraev, I. S.; Mader, J.; Tandecki, M.; Van Gorp, S.; Wauters, F.; Weinheimer, Ch.; Wenander, F.; Severijns, N.

    2011-03-01

    The WITCH experiment (Weak Interaction Trap for CHarged particles) will search for exotic interactions by investigating the β - ν angular correlation via the measurement of the recoil energy spectrum after β -decay. As a first step the recoil ions from the β-_{} -decay of 124In stored in a Penning trap have been detected. The evidence for the detection of recoil ions is shown and the properties of the ion cloud that forms the radioactive source for the experiment in the Penning trap are presented.

  2. Modeling and Measurement of 39Ar Recoil Loss From Biotite as a Function of Grain Dimensions

    NASA Astrophysics Data System (ADS)

    Paine, J. H.; Nomade, S.; Renne, P. R.

    2004-12-01

    The call for age measurements with less than 1 per mil error puts a demand upon geochronologists to be aware of and quantify a number of problems which were previously negligible. One such factor is 39Ar recoil loss during sample irradiation, a phenomenon which is widely assumed to affect only unusually small crystals having exceptionally high surface/volume ratios. This phenomenon has important implications for thermochronologic studies seeking to exploit a range of closure temperatures arising from variable diffusion radii. Our study focuses on biotite, in which spatial isotope distributions cannot be reliably recovered by stepwise heating and which therefore lack recoil-diagnostic age spectrum behavior. Previous work by Renne et al. [Application of a deuteron-deuteron (D-D) neutron generator to 40Ar/39Ar geochronology, Applied Radiation and Isotopes, in press] used the SRIM code to calculate a ˜20% 39Ar recoil loss from the outermost 0.25 μ m of an infinite slab of phyllosillicate. This result is applied to measured grains of the biotite standard GA1550, a hypabyssal granite from the Mount Dromedary Complex, Australia. We measure the thickness and surface area of 166 grains and approximate the shape of each grain as a cylinder. Grain thickness ranges from 3 to 210 μ m, with an average grain radius of 350 μ m. We predict the amount of 39Ar recoil loss from each grain, finding an expected age error >0.1 % for grains thinner than 150 μ m, a >1% error for grain less than 10 μ m thick, and up to a 3% error for grains less than 3 μ m thick. These modeling results will be tested by analysis of the measured grains after irradiation in the Oregon State University TRIGA reactor. It is important to either account for 39Ar loss in thin biotite grains, or use sufficiently thick ones so that recoil loss is negligible. Our results indicate that only biotite grains thicker than 150 μ m should be used for neutron fluence monitoring in order to avoid bias greater than the

  3. Vector correlations in photodissociation of polarized polyatomic molecules beyond the axial recoil limit.

    PubMed

    Krasilnikov, Mikhail B; Kuznetsov, Vladislav V; Suits, Arthur G; Vasyutinskii, Oleg S

    2011-05-14

    We present the full quantum mechanical theory of the angular momentum distributions of photofragments produced in photolysis of oriented/aligned parent polyatomic molecules beyond the axial recoil limit. This paper generalizes the results of Underwood and Powis(28,29) to the case of non-axial recoil photodissociation of an arbitrary polyatomic molecule. The spherical tensor approach is used throughout this paper. We show that the recoil angular distribution of the angular momentum polarization of each of the photofragments can be presented in a universal spherical tensor form valid for photolysis in diatomic or polyatomic molecules, irrespective of the reaction mechanism. The angular distribution can be written as an expansion over the Wigner D-functions in terms of the set of the anisotropy-transforming coefficients c(K(i)q(i))(K) (k(d), K(0)) which contain all of the information about the photodissociation dynamics and can be either determined from experiment, or computed from quantum mechanical theory. An important new conservation rule is revealed through the analysis, namely that the component q(i) of the initial reagent polarization rank K(i) and the photofragment polarization rank K onto the photofragment recoil direction k is preserved in any photolysis reaction. Both laboratory and body frame expressions for the recoil angle dependence of the photofragment angular momentum polarization are presented. The parent molecule polarization is shown to lead to new terms in the obtained photofragment angular distributions compared with the isotropic case. In particular, the terms with |q(i)| > 2 can appear which are shown to manifest angular momentum helicity non-conservation in the reaction. The expressions for the coefficients c(K(i)q(i))(K) (k(d), K(0)) have been simplified using the quasiclassical approximation in the high-J limit which allows for introducing the dynamical functions and the rotation factors which describe the decreasing of the photofragment

  4. A statistical method to search for recoiling supermassive black holes in active galactic nuclei

    NASA Astrophysics Data System (ADS)

    Raffai, P.; Haiman, Z.; Frei, Z.

    2016-01-01

    We propose an observational test for gravitationally recoiling supermassive black holes (BHs) in active galactic nuclei, based on a correlation between the velocities of BHs relative to their host galaxies, |Δv|, and their obscuring dust column densities, Σdust (both measured along the line of sight). We use toy models for the distribution of recoil velocities, BH trajectories, and the geometry of obscuring dust tori in galactic centres, to simulate 2.5 × 105 random observations of recoiling quasars. BHs with recoil velocities comparable to the escape velocity from the galactic centre remain bound to the nucleus, and do not fully settle back to the centre of the torus due to dynamical friction in a typical quasar lifetime. We find that |Δv| and Σdust for these BHs are positively correlated. For obscured (Σdust > 0) and for partially obscured (0 < Σdust ≲ 2.3 g m-2) quasars with |Δv| ≥ 45 km s-1, the sample correlation coefficient between log10(|Δv|) and Σdust is r45 = 0.28 ± 0.02 and r45 = 0.13 ± 0.02, respectively. Allowing for random ± 100 km s- 1 errors in |Δv| unrelated to the recoil dilutes the correlation for the partially obscured quasars to r45 = 0.026 ± 0.004 measured between |Δv| and Σdust. A random sample of ≳ 3500 obscured quasars with |Δv| ≥ 45 km s-1 would allow rejection of the no-correlation hypothesis with 3σ significance 95 per cent of the time. Finally, we find that the fraction of obscured quasars, {F_obs} (|Δv|), decreases with |Δv| from {F_obs} (<10 km s-1) ≳ 0.8 to {F_obs} (>103 km s-1) ≲ 0.4. This predicted trend can be compared to the observed fraction of type II quasars, and can further test combinations of recoil, trajectory, and dust torus models.

  5. Optimization of separation and detection conditions for comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry analysis of polychlorinated dibenzo-p-dioxins and dibenzofurans

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The 2,3,7,8-substituted polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are among the most toxic compounds known. The current predominant method of analysis is too expensive and cumbersome, and comprehensive gas chromatography coupled to time-of-flight mass spect...

  6. Electrokinetic supercharging-electrospray ionisation-mass spectrometry for separation and on-line preconcentration of hypolipidaemic drugs in water samples.

    PubMed

    Dawod, Mohamed; Breadmore, Michael C; Guijt, Rosanne M; Haddad, Paul R

    2010-04-01

    Electrokinetic supercharging, a powerful on-line preconcentration technique in CE, was for the first time hyphenated with ESI-MS for the on-line concentration and separation of five hypolipidaemic drugs. The electrophoretic separation was performed in a co-EOF mode using the EOF reversal agent, hexadimethrine bromide, in ammonium bicarbonate electrolyte, pH 9.00. The ionic strength and the amount of methanol in the buffer were optimised in a multivariate manner using artificial neural networks, with the optimal conditions being 60 mM ammonium bicarbonate containing 60% methanol, providing baseline resolution of the five hypolipidaemics within 20 min. Using electrokinetic supercharging, the sensitivity of the method was improved 1000-fold over a conventional injection under field-amplified sample stacking conditions with LODs of 180 ng/L. This is the first report of the separation of hypolipidaemics by CE. The developed method was validated and then applied to the determination of the target drugs in water samples from Hobart city. PMID:20349512

  7. Separation and characterization of bufadienolides in toad skin using two-dimensional normal-phase liquid chromatography×reversed-phase liquid chromatography coupled with mass spectrometry.

    PubMed

    Zhang, Yun; Jin, Hongli; Li, Xiaolong; Zhao, Jianqiang; Guo, Xiujie; Wang, Jixia; Guo, Zhimou; Zhang, Xiuli; Tao, Yanduo; Liu, Yanfang; Chen, Deliang; Liang, Xinmiao

    2016-07-15

    Bufadienolides possess various bioactivities especially antitumor. Due to the high structural diversity, the separation of bufadienolides often suffers from coelution problem on conventional RP columns. In this work, an off-line two-dimensional normal-phase liquid chromatography×reversed-phase liquid chromatography (2D-NPLC×RPLC) method was developed to separate and characterize bufadienolides in toad skin. Several RP and NP columns were evaluated with five reference bufadienlides. The XUnion C18 and XAmide columns exhibited superior chromatographic performances for bufadienlide separation, and were selected in RPLC and NPLC, respectively. RPLC was used in the second-dimension for the good compatibility with MS, while NPLC was adopted in the first-dimension. The orthogonality of the 2D-NPLC×RPLC system was investigated by the geometric approach using fifteen bufadienolide mixtures. The result was 49.6%, demonstrating reasonable orthogonality of this 2D-LC system. By combining the 2D-LC system with MS, 64 bufadienlides including 33 minor ones and 11 pairs of isomers in toad skin were identified. This off-line 2D-NPLC×RPLC allowed to solve the coelution problem of bufadienlides in one-dimension RPLC, and thus facilitated the identification significantly. PMID:26621782

  8. Experimental designs for modeling retention patterns and separation efficiency in analysis of fatty acid methyl esters by gas chromatography-mass spectrometry.

    PubMed

    Skartland, Liv Kjersti; Mjøs, Svein A; Grung, Bjørn

    2011-09-23

    The retention behavior of components analyzed by chromatography varies with instrumental settings. Being able to predict how changes in these settings alter the elution pattern is useful, both with regards to component identification, as well as with regards to optimization of the chromatographic system. In this work, it is shown how experimental designs can be used for this purpose. Different experimental designs for response surface modeling of the separation of fatty acid methyl esters (FAME) as function of chromatographic conditions in GC have been evaluated. Full factorial, central composite, Doehlert and Box-Behnken designs were applied. A mixture of 38 FAMEs was separated on a polar cyanopropyl substituted polysilphenylene-siloxane phase capillary column. The temperature gradient, the start temperature of the gradient, and the carrier gas velocity were varied in the experiments. The modeled responses, as functions of chromatographic conditions, were retention time, retention indices, peak widths, separation efficiency and resolution between selected peak pairs. The designs that allowed inclusion of quadratic terms among the predictors performed significantly better than factorial design. Box-Behnken design provided the best results for prediction of retention, but the differences between the central composite, Doehlert and Box-Behnken designs were small. Retention indices could be modeled with much better accuracy than retention times. However, because the errors of predicted tR of closely eluting peaks were highly correlated, models of resolution (Rs) that were based on retention time had errors in the same range as corresponding models based on ECL. PMID:21851946

  9. Simultaneous electrophoretic concentration and separation of herbicides in beer prior to stacking capillary electrophoresis UV and liquid chromatography-mass spectrometry.

    PubMed

    Wuethrich, Alain; Haddad, Paul R; Quirino, Joselito P

    2016-05-01

    Simultaneous electrophoretic concentration and separation (SECS) was used as a simple and environmental friendly sample preparation strategy for herbicides in beer samples. An electric field was used to facilitate the separation and concentration of the analytes based on their charge from a 20 mL sample of diluted beer into two separate 20 μL aliquots of an acceptor electrolyte housed inside a micropipette. The anionic organophosphonate and cationic quaternary ammonium herbicides were concentrated in the anodic and cathodic pipette, respectively. Under optimized conditions, SECS was completed in 30 min at an applied voltage of 150 V, which provided analyte concentration factors of up to 90. After sample preparation, the SECS concentrate of cationic and anionic herbicides was analyzed by stacking CE with UV detection and also by LC-MS, respectively. The method detection limit for the diluted and undiluted sample was as low as 3 and 15 ng/mL, respectively. The method was linear over two orders of concentration with repeatability and intermediate precision of better than 5.8 and 7.0%RSD, respectively. Accuracy values were between 91.0-115.1%. PMID:26921124

  10. Selective separation of fluorinated compounds from complex organic mixtures by pyrolysis-comprehensive two-dimensional gas chromatography coupled to high-resolution time-of-flight mass spectrometry.

    PubMed

    Nakajima, Yoji; Arinami, Yuko; Yamamoto, Kiyoshi

    2014-12-29

    The usefulness of comprehensive two-dimensional gas chromatography (GC×GC) was demonstrated for the selective separation of fluorinated compounds from organic mixtures, such as kerosene/perfluorokerosene mixtures, pyrolysis products derived from polyethylene/ethylene-tetrafluoroethylene alternating copolymer mixture and poly[2-(perfluorohexyl)ethyl acrylate]. Perfluorocarbons were completely separated from hydrocarbons in the two-dimensional chromatogram. Fluorohydrocarbons in the pyrolysis products of polyethylene/ethylene-tetrafluoroethylene alternating copolymer mixture were selectively isolated from their hydrocarbon counterparts and regularly arranged according to their chain length and fluorine content in the two-dimensional chromatogram. A reliable structural analysis of the fluorohydrocarbons was achieved by combining effective GC×GC positional information with accurate mass spectral data obtained by high-resolution time-of-flight mass spectrometry (HRTOF-MS). 2-(Perfluorohexyl)ethyl acrylate monomer, dimer, and trimer as well as 2-(perfluorohexyl)ethyl alcohol in poly[2-(perfluorohexyl)ethyl acrylate] pyrolysis products were detected in the bottommost part of the two-dimensional chromatogram with separation from hydrocarbons possessing terminal structure information about the polymer, such as α-methylstyrene. Pyrolysis-GC×GC/HRTOF-MS appeared particularly suitable for the characterization of fluorinated polymer microstructures, such as monomer sequences and terminal groups. PMID:25482852

  11. Atomistic Simulation of Track Formation by Energetic Recoils in Zircon

    SciTech Connect

    Moreira, Pedro A.; Devanathan, Ramaswami; Weber, William J.

    2010-09-17

    We have performed classical molecular dynamics simulations of fission track formation in zircon. We simulated the passage of a swift heavy ion through crystalline zircon using cylindrical thermal spikes with energy deposition (dE/dx) of 2.5 to 12.8 keV/nm and radius of 3 nm. At a low dE/dx of 2.55 keV/nm, the structural damage recovered almost completely and a damage track was not produced. At higher values of dE/dx, tracks were observed and the radius of the track increased with increasing dE/dx. Our structural analysis shows amorphization in the core of the track and phase separation into Si-rich regions near the center of the track and Zr-rich regions near the periphery. These simulations establish a threshold dE/dx for fission-track formation in zircon that is relevant to thermo-chronology and nuclear waste immobilization.

  12. Recoil-ion momentum spectroscopy for He2+ + He electron capture reactions

    NASA Astrophysics Data System (ADS)

    Alessi, M.; Focke, P.; Otranto, S.

    2015-01-01

    Electron capture reactions for 3He2+ collisions on He at impact energies in the range 40 keV-300 keV have been studied using the Cold Target Recoil-Ion Momentum Spectroscopy setup which has recently became operational at the Centro Atomico Bariloche. State-selective charge exchange cross sections were obtained and in this work we present recoil-ion transverse momentum distributions. For targets with residual thermal motion, we show that the implementation of a back-projection algorithm based on the transverse momentum distribution component along a direction perpendicular to the jet direction provides results in agreement with those obtained by using previously cooled targets. Present results nicely fit the gaps in the datasets already published by other laboratories and are found to be in good agreement with classical trajectory Monte Carlo simulations.

  13. A predictive theory for elastic scattering and recoil of protons from 4He

    DOE PAGESBeta

    Hupin, Guillaume; Quaglioni, Sofia; Navratil, Petr

    2014-12-08

    Low-energy cross sections for elastic scattering and recoil of protons from 4He nuclei (also known as α particles) are calculated directly by solving the Schrodinger equation for five nucleons interacting through accurate two- and three-nucleon forces derived within the framework of chiral effective field theory. Precise knowledge of these processes at various proton backscattering/recoil angles and energies is needed for the ion-beam analysis of numerous materials, from the surface layers of solids, to thin films, to fusion-reactor materials. Indeed, the same elastic scattering process, in two different kinematic configurations, can be used to probe the concentrations and depth profiles ofmore » either hydrogen or helium. Furthermore, we compare our results to available experimental data and show that direct calculations with modern nuclear potentials can help to resolve remaining inconsistencies among data sets and can be used to predict these cross sections when measurements are not available.« less

  14. Predictive theory for elastic scattering and recoil of protons from 4He

    NASA Astrophysics Data System (ADS)

    Hupin, Guillaume; Quaglioni, Sofia; Navrátil, Petr

    2014-12-01

    Low-energy cross sections for elastic scattering and recoil of protons from 4He nuclei (also known as α particles) are calculated directly by solving the Schrödinger equation for five nucleons interacting through accurate two- and three-nucleon forces derived within the framework of chiral effective field theory. Precise knowledge of these processes at various proton backscattering/recoil angles and energies is needed for the ion-beam analysis of numerous materials, from the surface layers of solids, to thin films, to fusion-reactor materials. Indeed, the same elastic scattering process, in two different kinematic configurations, can be used to probe the concentrations and depth profiles of either hydrogen or helium. We compare our results to available experimental data and show that direct calculations with modern nuclear potentials can help to resolve remaining inconsistencies among data sets and can be used to predict these cross sections when measurements are not available.

  15. A predictive theory for elastic scattering and recoil of protons from 4He

    SciTech Connect

    Hupin, Guillaume; Quaglioni, Sofia; Navratil, Petr

    2014-12-08

    Low-energy cross sections for elastic scattering and recoil of protons from 4He nuclei (also known as α particles) are calculated directly by solving the Schrodinger equation for five nucleons interacting through accurate two- and three-nucleon forces derived within the framework of chiral effective field theory. Precise knowledge of these processes at various proton backscattering/recoil angles and energies is needed for the ion-beam analysis of numerous materials, from the surface layers of solids, to thin films, to fusion-reactor materials. Indeed, the same elastic scattering process, in two different kinematic configurations, can be used to probe the concentrations and depth profiles of either hydrogen or helium. Furthermore, we compare our results to available experimental data and show that direct calculations with modern nuclear potentials can help to resolve remaining inconsistencies among data sets and can be used to predict these cross sections when measurements are not available.

  16. Alpha-recoil damage: Relation to isotopic disequilibrium and leaching of radionuclides

    SciTech Connect

    Fleischer, R.L. )

    1988-06-01

    The observation by Raabe et al. (1973) of large differences between the solubilities of isotopically different plutonium dioxides, has led to the recognition of preferential etching of recoil damage as a widespread phenomenon for alpha-active radionuclides. The associated preferential solubility of the products of alpha decay, along with direct recoil ejection, are the two specific microscopic mechanisms that are documented as causes of isotopic disequilibrium in the U and Th decay series. Similarly, leaching plays a significant role in releasing {sup 222}Rn from natural substances, {sup 222}Rn being the alpha-decay product of {sup 226}Ra. The average annealing time in nature of the damage sites can be inferred from the extent of isotopic disequilibrium for different isotopic pairs in the Th and U decay chains.

  17. A coherent understanding of low-energy nuclear recoils in liquid xenon

    SciTech Connect

    Sorensen, Peter

    2010-09-01

    Liquid xenon detectors such as XENON10 and XENON100 obtain a significant fraction of their sensitivity to light (∼<10 GeV) particle dark matter by looking for nuclear recoils of only a few keV, just above the detector threshold. Yet in this energy regime a correct treatment of the detector threshold and resolution remains unclear. The energy dependence of the scintillation yield of liquid xenon for nuclear recoils also bears heavily on detector sensitivity, yet numerous measurements have not succeeded in obtaining concordant results. In this article we show that the ratio of detected ionization to scintillation can be leveraged to constrain the scintillation yield. We also present a rigorous treatment of liquid xenon detector threshold and energy resolution. Notably, the effective energy resolution differs significantly from a simple Poisson distribution. We conclude with a calculation of dark matter exclusion limits, and show that existing data from liquid xenon detectors strongly constrain recent interpretations of light dark matter.

  18. Development of bubble chambers with enhanced stability and sensitivity to low-energy nuclear recoils

    SciTech Connect

    Bolte, W.J.; Collar, Juan I.; Crisler, M.; Hall, J.; Holmgren, D.; Nakazawa, D.; Odom, B.; O'Sullivan, K.; Plunkett, R.; Ramberg, E.; Raskin, A.; Sonnenschein, A.; Vieira, J.D.; /Chicago U., EFI /KICP, Chicago /Fermilab

    2005-03-01

    The viability of using a Bubble Chamber for rare event searches and in particular for the detection of dark matter particle candidates is considered. Techniques leading to the deactivation of inhomogeneous nucleation centers and subsequent enhanced stability in such a detector are described. Results from prototype trials indicate that sensitivity to low-energy nuclear recoils like those expected from Weakly Interacting Massive Particles can be obtained in conditions of near total insensitivity to minimum ionizing backgrounds. An understanding of the response of superheated heavy refrigerants to these recoils is demonstrated within the context of existing theoretical models. We comment on the prospects for the detection of supersymmetric dark matter particles with a large CF{sub 3}I chamber.

  19. Digital characterization of recoil charged-particle tracks for neutron measurements

    SciTech Connect

    Turner, J.E.; Hunter, S.R.; Hamm, R.N.; Wright, H.A.; Hurst, G.S.; Gibson, W.A.

    1988-01-01

    We are developing a new optical ionization detector for imaging the track of a charged neutron-recoil particle in a gas. Electrons produced in the path of the recoil particle are excited by an external, high-voltage, RF, electric field of short duration. Their oscillatory motion causes ionization and excitation of nearby gas molecules, which then emit light in subsequent de-excitation. Two digital cameras image the optical radiation across two perpendicular planes and analyze it for the numbers of electrons in various volume elements along the track. These numbers constitute the digital characterization of the track. This information can then be used to infer the energy deposited in the track and the track LET in the gas. We have now observed alpha-particle tracks in a chamber utilizing these principles. The application of such a device for neutron dosimetry and neutron spectrometry will be described. 4 refs., 3 figs.

  20. Low energy electron/recoil discrimination for directional Dark Matter detection

    SciTech Connect

    Billard, J.; Mayet, F.; Santos, D. E-mail: mayet@lpsc.in2p3.fr

    2012-07-01

    Directional detection is a promising Dark Matter search strategy. Even though it could accommodate to a sizeable background contamination, electron/recoil discrimination remains a key and challenging issue as for direction-insensitive detectors. The measurement of the 3D track may be used to discriminate electrons from nuclear recoils. While a high rejection power is expected above 20 keV ionization, a dedicated data analysis is needed at low energy. After identifying discriminant observables, a multivariate analysis, namely a Boosted Decision Tree, is proposed, enabling an efficient event tagging for Dark Matter search. We show that it allows us to optimize rejection while keeping a rather high efficiency which is compulsory for rare event search.With respect to a sequential analysis, the rejection is about ∼ 20 times higher with a multivariate analysis, for the same Dark Matter exclusion limit.

  1. In-Line Separation by Capillary Electrophoresis Prior to Analysis by Top-Down Mass Spectrometry Enables Sensitive Characterization of Protein Complexes

    PubMed Central

    2015-01-01

    Intact protein analysis via top-down mass spectrometry (MS) provides a bird’s eye view over the protein complexes and complex protein mixtures with the unique capability of characterizing protein variants, splice isoforms, and combinatorial post-translational modifications (PTMs). Here we applied capillary electrophoresis (CE) through a sheathless CE–electrospray ionization interface coupled to an LTQ Velos Orbitrap Elite mass spectrometer to analyze the Dam1 complex from Saccharomyces cerevisiae. We achieved a 100-fold increase in sensitivity compared to a reversed-phase liquid chromatography coupled MS analysis of recombinant Dam1 complex with a total loading of 2.5 ng (12 amol). N-terminal processing forms of individual subunits of the Dam1 complex were observed as well as their phosphorylation stoichiometry upon Mps1p kinase treatment. PMID:25382489

  2. Inclusive production of H\\rightarrow b\\bar{b} plus a recoil for the LHC Run-II

    NASA Astrophysics Data System (ADS)

    Gutierrez, Nicolas

    2016-07-01

    This letter presents a study of the inclusive production of H→ b\\bar{b} plus a recoil, using simulated samples of pp collisions at \\sqrt{s}=14 \\text{TeV} for an integrated luminosity in the range between 30 \\text{fb}-1 and 3 \\text{ab}-1 . The case for experiments to include un-prescaled b-tag multijet triggers for this topology is made and the ideal jet thresholds are discussed. The sensitivity to the Standard Model Higgs boson with a transverse momentum of at least 200 GeV is evaluated with respect to a continuous background, dominated by multijet processes. The mass of b-jet-pairs is analysed, quoting sensitivity to cross-sections in the range from 1 to 2 pb, for 100 \\text{fb}-1 , covering the total Higgs-boson production cross-section of 1.8 pb. The trigger strategy presented in this letter is compared to triggers already in use, showing an increase on the signal efficiency for masses below 200 GeV and a performance comparable to a logical OR of all the currently available akin triggers for higher masses. The robustness of the expected sensitivity against systematic uncertainties is estimated by considering various typical sources, such as those on the fitting parameters of the continuous background, shape uncertainties affecting the signal acceptance and the background modelling. The accuracy of the Higgs-boson production cross-section measurements is also discussed, quoting sensitivity to deviations of 50% for 100 \\text{fb}-1 and 10% for 3 \\text{ab}-1 .

  3. Separation techniques.

    PubMed

    Duke, T

    1998-10-01

    The past two years have seen continued development of capillary electrophoresis methods. The separation performance of flowable sieving media now equals, and in some respects exceeds, that provided by gels. The application of microfabrication techniques to separation science is gaining pace. There is a continuing trend towards miniaturization and integration of separation with preparative or analytical steps. Innovative separation methods based on microfabrication technology include electrophoresis in purpose-designed molecular sieves, dielectric, trapping using microelectrodes, and force-free motion in Brownian ratchets. PMID:9818184

  4. Integral cross section measurements and product recoil velocity distributions of Xe2+ + N2 hyperthermal charge-transfer collisions

    NASA Astrophysics Data System (ADS)

    Hause, Michael L.; Prince, Benjamin D.; Bemish, Raymond J.

    2016-07-01

    Charge exchange from doubly charged rare gas cations to simple diatomics proceeds with a large cross section and results in populations of many vibrational and electronic product states. The charge exchange between Xe2+ and N2, in particular, is known to create N2 + in both the A and B electronic states. In this work, we present integral charge exchange cross section measurements of the Xe2+ + N2 reaction as well as axial recoil velocity distributions of the Xe+ and N2 + product ions for collision energies between 0.3 and 100 eV in the center-of-mass (COM) frame. Total charge-exchange cross sections decrease from 70 Å2 to about 40 Å2 with increasing collision energy through this range. Analysis of the axial velocity distributions indicates that a Xe2+ - N2 complex exists at low collision energies but is absent by 17.6 eV COM. Analysis of the axial velocity distributions reveals evidence for complexes with lifetimes comparable to the rotational period at low collision energies. The velocity distributions are consistent with quasi-resonant single charge transfer at high collision energies.

  5. Integral cross section measurements and product recoil velocity distributions of Xe(2+) + N2 hyperthermal charge-transfer collisions.

    PubMed

    Hause, Michael L; Prince, Benjamin D; Bemish, Raymond J

    2016-07-28

    Charge exchange from doubly charged rare gas cations to simple diatomics proceeds with a large cross section and results in populations of many vibrational and electronic product states. The charge exchange between Xe(2+) and N2, in particular, is known to create N2 (+) in both the A and B electronic states. In this work, we present integral charge exchange cross section measurements of the Xe(2+) + N2 reaction as well as axial recoil velocity distributions of the Xe(+) and N2 (+) product ions for collision energies between 0.3 and 100 eV in the center-of-mass (COM) frame. Total charge-exchange cross sections decrease from 70 Å(2) to about 40 Å(2) with increasing collision energy through this range. Analysis of the axial velocity distributions indicates that a Xe(2+) - N2 complex exists at low collision energies but is absent by 17.6 eV COM. Analysis of the axial velocity distributions reveals evidence for complexes with lifetimes comparable to the rotational period at low collision energies. The velocity distributions are consistent with quasi-resonant single charge transfer at high collision energies. PMID:27475363

  6. What Can We Learn From Proton Recoils about Heavy-Ion SEE Sensitivity?

    NASA Technical Reports Server (NTRS)

    Ladbury, Raymond L.

    2016-01-01

    The fact that protons cause single-event effects (SEE) in most devices through production of light-ion recoils has led to attempts to bound heavy-ion SEE susceptibility through use of proton data. Although this may be a viable strategy for some devices and technologies, the data must be analyzed carefully and conservatively to avoid over-optimistic estimates of SEE performance. We examine the constraints that proton test data can impose on heavy-ion SEE susceptibility.

  7. Recoil-proton polarization in high-energy deuteron photodisintegration with circularly plarized photons.

    SciTech Connect

    Jiang, X.; Arrington, J.; Benmokhtar, F.; Camsonne, A.; Chen, J. P.; Holt, R. J.; Qattan, I. A.; Reimer, P. E.; Schulte, E. C.; Wijesooriya, K.; Physics; Rutgers Univ.; Univ. Blaise Pascal; Thomas Jefferson National Accelerator Facility

    2007-05-01

    We measured the angular dependence of the three recoil-proton polarization components in two-body photodisintegration of the deuteron at a photon energy of 2 GeV. These new data provide a benchmark for calculations based on quantum chromodynamics. Two of the five existing models have made predictions of polarization observables. Both explain the longitudinal polarization transfer satisfactorily. Transverse polarizations are not well described, but suggest isovector dominance.

  8. Recoil-Proton Polarization in High-Energy Deuteron Photodisintegration with Circularly Polarized Photons

    SciTech Connect

    Jiang, X.; Benmokhtar, F.; Glashauser, C.; McCormick, K.; Ransome, R. D.; Arrington, J.; Holt, R. J.; Reimer, P. E.; Schulte, E. C.; Wijesooriya, K.; Camsonne, A.

    2007-05-04

    We measured the angular dependence of the three recoil-proton polarization components in two-body photodisintegration of the deuteron at a photon energy of 2 GeV. These new data provide a benchmark for calculations based on quantum chromodynamics. Two of the five existing models have made predictions of polarization observables. Both explain the longitudinal polarization transfer satisfactorily. Transverse polarizations are not well described, but suggest isovector dominance.

  9. Recoil-Proton Polarization in High-Energy Deuteron Photodisintegration with Circularly Polarized Photons

    SciTech Connect

    X. Jiang; J. Arrington; F. Benmokhtar; A. Camsonne; J. P. Chen; S. Choi; E. Chudakov; F. Cusanno; A. Deur; D. Dutta; F. Garibaldi; D. Gaskell; O. Gayou; R. Gilman; C. Glashauser; D. Hamilton; O. Hansen; D. W. Higinbotham; R. J. Holt; C. W. de Jager; M. K. Jones; L. J. Kaufman; E. R. Kinney; K. Kramer; L. Lagamba; R. de Leo; J. Lerose; D. Lhuillier; R. Lindgren; N. Liyanage; K. McCormick; Z.-E. Meziani; R. Michaels; B. Moffit; P. Monaghan; S. Nanda; K. D. Paschke; C. F. Perdrisat; V. Punjabi; I. A. Qattan; R. D. Ransome; P. E. Reimer; B. Reitz; A. Saha; E. C. Schulte; R. Sheyor; K. Slifer; P. Solvignon; V. Sulkosky; G. M. Urciuoli; E. Voutier; K. Wang; K. Wijesooriya; B. Wojtsekhowski; and L. Zhu

    2007-05-01

    We measured the angular dependence of the three recoil-proton polarization components in two-body photodisintegration of the deuteron at a photon energy of 2 GeV. These new data provide a benchmark for calculations based on quantum chromodynamics. Two of the five existing models have made predictions of polarization observables. Both explain the longitudinal polarization transfer satisfactorily. Transverse polarizations are not well described, but suggest isovector dominance.

  10. Angular dependence of recoil proton polarization in high-energy \\gamma d \\to p n

    SciTech Connect

    X. Jiang; J. Arrington; F. Benmokhtar; A. Camsonne; J.P. Chen; S. Choi; E. Chudakov; F. Cusanno; A. Deur; D. Dutta; F. Garibaldi; D. Gaskell; O. Gayou; R. Gilman; C. Glashauser; D. Hamilton; O. Hansen; D.W. Higinbotham; R.J. Holt; C.W. de Jager; M.K. Jones; L.J. Kaufman; E.R. Kinney; K. Kramer; L. Lagamba; R. de Leo; J. Lerose; D. Lhuillier; R. Lindgren; N. Liyanage; K. McCormick; Z.-E. Meziani; R. Michaels; B. Moffit; P. Monaghan; S. Nanda; K.D. Paschke; C.F. Perdrisat; V. Punjabi; I.A. Qattan; R.D. Ransome; P.E. Reimer; B. Reitz; A. Saha; E.C. Schulte; R. Sheyor; K. Slifer; P. Solvignon; V. Sulkosky; G.M. Urciuoli; E. Voutier; K. Wang; K. Wijesooriya; B. Wojtsekhowski; L. Zhu

    2007-02-26

    We measured the angular dependence of the three recoil proton polarization components in two-body photodisintegration of the deuteron at a photon energy of 2 GeV. These new data provide a benchmark for calculations based on quantum chromodynamics. Two of the five existing models have made predictions of polarization observables. Both explain the longitudinal polarization transfer satisfactorily.. Transverse polarizations are not well described, but suggest isovector dominance.

  11. Elastic recoil detection analysis of hydrogen with 7Li ions using a polyimide foil as a thick hydrogen reference

    NASA Astrophysics Data System (ADS)

    Pelicon, Primož; Razpet, Alenka; Markelj, Sabina; Čadež, Iztok; Budnar, Miloš

    2005-01-01

    Elastic recoil detection analysis (ERDA) with an absorber foil using a 4.2 MeV 7Li2+ beam was utilized for evaluation of hydrogen depth profiles. Since recoil cross-sections when using Li ions as projectiles are not well known, the energy dependent ratio between the experimental yield and the yield calculated using the Rutherford recoil cross-section was obtained from an ERDA spectrum of a thick polyimide (Kapton) sample. It was estimated that this ratio does not significantly depend on sample composition. Therefore it was used for correction of measured spectra analyzed by existing simulation and evaluation programs in which the Rutherford recoil cross-sections were applied. The correction procedure has been verified in round-robin measurements of well-characterized Si:H thin layers. Application of the method for determination of a hydrogen depth concentration profile in hydrogen-containing graphite samples is presented.

  12. Characterization of Low-mass, Wide-separation Substellar Companions to Stars in Upper Scorpius: Near-infrared Photometry and Spectroscopy

    NASA Astrophysics Data System (ADS)

    Lachapelle, François-René; Lafrenière, David; Gagné, Jonathan; Jayawardhana, Ray; Janson, Markus; Helling, Christiane; Witte, Soeren

    2015-03-01

    We present new 0.9-2.45 μm spectroscopy (R˜ 1000 ), and Y, J, H, Ks, {{L}\\prime } photometry, obtained at Gemini North, of three low-mass brown dwarf companions on wide orbits around young stars of the Upper Scorpius OB association: HIP 78530 B, [PGZ 2001] J161031.9-191305 B, and GSC 06214-00210 B. We use these data to assess the companions’ spectral type, temperature, surface gravity, and mass, as well as the ability of the BT-SETTL and Drift-Phoenix atmosphere models to reproduce the spectral features of young substellar objects. For completeness, we also analyze the archival spectroscopy and photometry of the Upper Scorpius planetary mass companion 1RXS J160929.1-210524 b. Based on a comparison with model spectra we find that the companions, in the above order, have effective temperatures of 2700 ± 100, 2500 ± 200, 2300 ± 100, and 1700 ± 100 K. These temperatures are consistent with our inferred spectral types, respectively M7 β, M9 γ, M9 γ, and L4 γ, obtained from spectral indices and comparisons with templates. From bolometric luminosities estimated from atmosphere model spectra adjusted to our photometry, and using evolution models at 5-10 Myr, we estimate masses of 21-25, 28-70, 14-17, and 7-12 MJup, respectively. [PGZ 2001] J161031.9-191305 B appears significantly overluminous for its inferred temperature, which explains its higher mass estimate. Synthetic spectra based on the BT-Settl and Drift-Phoenix atmosphere models generally offer a good fit to our observed spectra, although our analysis has highlighted a few problems. For example, the best fits in the individual near-infrared bands occur at different model temperatures. Also, temperature estimates based on a comparison of the broadband magnitudes and colors of the companions to synthetic magnitudes from the models are systematically lower than the temperature estimates based on a comparison with synthetic spectra.

  13. Target separation of a new anti-tumor saponin and metabolic profiling of leaves of Panax notoginseng by liquid chromatography with eletrospray ionization quadrupole time-of-flight mass spectrometry.

    PubMed

    Mao, Qian; Yang, Jie; Cui, Xiu-Ming; Li, Jing-Jing; Qi, Yin-Tao; Zhang, Ping-Hu; Wang, Qiang

    2012-02-01

    A method coupling high-performance liquid chromatography (HPLC) with quadrupole time-of-flight mass spectrometers (QTOF-MS) using an eletrospray ionization (ESI) source was firstly developed for detection, characterization and guiding target separation of variants of protopanaxdiol saponin from leaves of Panax notoginseng. Under the guidance of LC-QTOF-MS, a new trace saponin was probed according to the precise elemental compositions of molecular ions and the fragmentation behavior, and then separated from the ethanol extract of the plant by a set of chromatographic methods. It was further confirmed by NMR experiments as 3-O-β-D-glucopyranoside-3β,l2β,23β-triol-20-ene-dammar (Pn-1). The cytotoxic assay showed that Pn-1 had relatively stronger anti-tumor effects against three tumor cell lines (NCI-H460, HepG2 and SGC-7901) than Rg₃, an approved clinical agent for cancer therapy. Meanwhile, based on accurate mass measurements within 5 ppm for each molecular ions and subsequent product ions, 48 saponins, including 40 protopanaxadiol saponins, 7 protopanaxatriol saponins and 1 oleanane saponin were identified. It is noted that the knowledge of the presence of abundant protopanaxadiol saponins in leaves of P. notoginseng may provide tools for a full understanding of the chemical diversity of secondary metabolites from the different parts of P. notoginseng. From the points of time consuming and accurate mass measurement capability, the LC-QTOF-MS is a highly powerful tool for screening and guiding target separation of new compounds in herbal extract, and thus benefits the speed of new drug discovery progress. PMID:22047761

  14. Separation and analysis of phenolic acids from Salvia miltiorrhiza and its related preparations by off-line two-dimensional hydrophilic interaction chromatography×reversed-phase liquid chromatography coupled with ion trap time-of-flight mass spectrometry.

    PubMed

    Sun, Wanyang; Tong, Ling; Miao, Jingzhuo; Huang, Jingyi; Li, Dongxiang; Li, Yunfei; Xiao, Hongting; Sun, Henry; Bi, Kaishun

    2016-01-29

    Salvia miltiorrhiza (SM) is one of the most widely used Traditional Chinese Medicine. Active constituents of SM mainly contain hydrophilic phenolic acids (PAs) and lipophilic tanshinones. However, due to the existing of multiple ester bonds and unsaturated bonds in the structures, PAs have numerous chemical conversion products. Many of them are so low-abundant that hard to be separated using conventional methods. In this study, an off-line two-dimensional liquid chromatography (2D-LC) method was developed to separate PAs in SM and its related preparations. In the first dimension, samples were fractionated by hydrophilic interaction chromatography (HILIC) (Acchrom×Amide, 4.6×250mm, 5μm) mainly based on the hydrogen bonding effects. The fractions were then separated on reversed-phase liquid chromatography (RP-LC) (Acquity HSS T3, 2.1×50mm, 1.7μm) according to hydrophobicity. For the selective identification of PAs, diode array detector (DAD) and electrospray ionization tandem ion trap time-of-flight mass spectrometry (ESI-IT-TOF-MS) were employed. Practical and effective peak capacities of all the samples were greater than 2046 and 1130, respectively, with the orthogonalities ranged from 69.7% to 92.8%, which indicated the high efficiency and versatility of this method. By utilizing the data post-processing techniques, including mass defect filter, neutral loss filter and product ion filter, a total of 265 compounds comprising 196 potentially new PAs were tentatively characterized. Twelve kinds of derivatives, mainly including glycosylated compounds, O-alkylated compounds, condensed compounds and hydrolyzed compounds, constituted the novelty of the newly identified PAs. The HILIC×RP-LC/TOF-MS system expanded our understanding on PAs of S. miltiorrhiza and its related preparations, which could also benefit the separation and characterization of polar constituents in complicated herbal extracts. PMID:26792448

  15. Einstein-Bohr recoiling double-slit gedanken experiment performed at the molecular level

    NASA Astrophysics Data System (ADS)

    Liu, Xiao-Jing; Miao, Quan; Gel'Mukhanov, Faris; Patanen, Minna; Travnikova, Oksana; Nicolas, Christophe; Ågren, Hans; Ueda, Kiyoshi; Miron, Catalin

    2015-02-01

    Double-slit experiments illustrate the quintessential proof for wave-particle complementarity. If information is missing about which slit the particle has traversed, the particle, behaving as a wave, passes simultaneously through both slits. This wave-like behaviour and corresponding interference is absent if ‘which-slit’ information exists. The essence of Einstein-Bohr's debate about wave-particle duality was whether the momentum transfer between a particle and a recoiling slit could mark the path, thus destroying the interference. To measure the recoil of a slit, the slits should move independently. We showcase a materialization of this recoiling double-slit gedanken experiment by resonant X-ray photoemission from molecular oxygen for geometries near equilibrium (coupled slits) and in a dissociative state far away from equilibrium (decoupled slits). Interference is observed in the former case, while the electron momentum transfer quenches the interference in the latter case owing to Doppler labelling of the counter-propagating atomic slits, in full agreement with Bohr's complementarity.

  16. Transport-theory approach to ion-beam mixing and recoil implantation

    SciTech Connect

    Manning, I. )

    1990-12-01

    Ion bombardment of an amorphous target in slab geometry is considered, and ion-beam mixing and recoil implantation evaluated in the binary-collision approximation. A fundamental equation for target-atom redistribution during ion bombardment is formulated, which relates the redistribution flux to the source function for the creation of energetic atomic recoils and their range distribution; for the analysis, this equation plays the role of the Boltzmann transport equation. Expanding the target-atom density in a power series and truncating at the second term yields a flux equation and closed expressions for coefficients of recoil implantation and of ion-beam mixing. The flux equation plays a role analogous to that of Fick's law in diffusion. Lattice relaxations are taken into account by introducing flux transformations between laboratory and marker coordinate frames. The closed expressions for the coefficients are calculated and compared with experiment. The binary-collision contribution to ion-beam mixing turns out to be larger than heretofore thought. A new mechanism for ion-beam mixing emerges, which turns out to make a very significant contribution. There are even cases where the new mechanism far outweighs the cascade-mixing mechanism, thought to be the major contributor to binary-collision ion-beam mixing.

  17. Nuclear Recoil Calibrations in the LUX Detector Using Direct and Backscattered D-D Neutrons

    NASA Astrophysics Data System (ADS)

    Rhyne, Casey; LUX Collaboration

    2016-03-01

    The LUX dark matter search experiment is a 350 kg two-phase liquid/gas xenon time projection chamber located at the 4850 ft level of the Sanford Underground Research Facility in Lead, SD. I will discuss the latest calibration of the nuclear recoil (NR) response in liquid xenon (LXe), performed in-situ in the LUX detector using mono-energetic 2.45 MeV neutrons produced via the Adelphi Technologies, Inc. DD108 D-D neutron generator. The calibration measured the NR charge yield in LXe (Qy) to 0.7 keVnr recoil energy with an absolute determination of deposited energy and the NR light yield in LXe (Ly) to recoil energies of 1.1 keVnr, both of which improve upon all previous measurements. I will then focus in depth on the extension of this calibration using a new technique for generating a beam of sub-300 keV quasi-mono-energetic neutrons via the backscatter of 2.45 MeV neutrons off a deuterium-based reflector. Current simulations work optimizing the technique, its advantages, and its impact on future research will be discussed, including the extension of the NR Qy calibration down to 0.14 keVnr, an independent NR Ly calibration, and an a priori estimate of the expected 8B solar neutrino-nucleus coherent scattering signal in the upcoming LUX-ZEPLIN experiment.

  18. Plasma-assisted Recoil Implantation for Shallow Boron Doping in Silicon

    NASA Astrophysics Data System (ADS)

    Liu, H. L.; Gearhart, S. S.; Booske, J. H.; Wang, W.

    1997-10-01

    An ion beam mixing technique is used to fabricate ultra-shallow p+/n junctions for the application of sub-micron CMOS source/drain formation. In this method, a thin boron layer is first sputtered onto the Si wafer. Then -3kV argon Plasma Source Ion Implantation (PSII) drives the boron atoms into the Si substrate by means of ion beam mixing. This process avoids the hazardous toxic gases, undesirable F co-implantation and F etching effects. Sub-100nm deep p+/n junctions have been formed with this method. Numerical simulations were performed to predict the recoiled boron profiles, which are in agreement with the experimental data. The boron sputter deposition process has been optimized. Auger electron spectroscopy (AES) confirms high purity of the deposited boron films. Numerical Simulations show that the B films with thickness ranging from 5nm to 10nm result in very similar recoiled B profiles. The thickness of 7.5nm is chosen for the deposited B layer to make the entire process more reproducible. Moreover, a part of the implantation damage will be contained in the B layer, which will be removed prior to the annealing step. This should help to alleviate the transient enhanced B diffusion. The research for the recoil implantation of 7.5nm thick B layer is currently underway.

  19. A Novel Nuclear Recoil Calibration in the LUX Detector Using a D-D Neutron Generator

    NASA Astrophysics Data System (ADS)

    Verbus, James; LUX Collaboration

    2015-04-01

    The LUX dark matter search experiment is a 350 kg two-phase liquid/gas xenon time projection chamber located at the 4850 ft level of the Sanford Underground Research Facility in Lead, SD. I will describe a novel calibration of nuclear recoils (NR) in liquid xenon (LXe) performed in-situ in the LUX detector using mono-energetic 2.45 MeV neutrons produced by a D-D neutron generator. This technique was used to measure the NR charge yield in LXe (Qy) to < 1 keV recoil energy with an absolute determination of the deposited energy. The LUX Qy result is a factor of × 5 lower in energy compared to any other previous measurement in the field, and provides a significant improvement in calibration uncertainties. We also present a measurement of the NR light yield in LXe (Leff) to recoil energies as low as ~ 2 keV using the LUX D-D data. The Leff result is also lower in energy with smaller uncertainties than has been previously achieved. These absolute, ultra-low energy calibrations of the NR signal yields in LXe are a clear confirmation of the detector response used for the first LUX WIMP search analysis. Strategies for extending this calibration technique to even lower energies and smaller uncertainties will be discussed.

  20. Nuclear Recoil Cross Sections from Time-dependent Studies of Two-Photon Double Ionization of Helium

    SciTech Connect

    Horner, Daniel A.; Rescigno, Thomas N.; McCurdy, C. William

    2009-12-21

    We examine the sensitivity of nuclear recoil cross sections produced by two-photon double ionization of helium to the underlying triple differential cross sections (TDCS) used in their computation. We show that this sensitivity is greatest in the energy region just below the threshold for sequential double ionization. Accurate TDCS, extracted from non-perturbative solutions of the time-dependent Schroedinger equation, are used here in new computations of the nuclear recoil cross section.

  1. Determination of concentration profiles by elastic recoil detection with a ΔE-E gas telescope and high energy incident heavy ions

    NASA Astrophysics Data System (ADS)

    Stoquert, J. P.; Guillaume, G.; Hage-Ali, M.; Grob, J. J.; Ganter, C.; Siffert, P.

    1989-12-01

    The Elastic Recoil Detection (ERD) method has been used to determine the profile of a wide range of elements simultaneously in a thin layer (1μm) with a depth resolution of a few hundred Å and high sensitivity. Z separation is achieved by a ΔE(gas)-E(solid) telescope. Results for 127I (up to 240 MeV) incident ions used to profile thin films of dielectrics (SiOxNyHz), amorphous semiconductors (a-GaAs: H) and superconductors (YBaCuO, BiSrCaCuO) are reported. It has been considered previously that ERD is of interest for analysis of light elements. We show that high energy heavy incident ions extend the field of application of the ERD method to all elements with an approximately constant depth resolution and sensitivity.

  2. The method for on-site determination of trace concentrations of methyl mercaptan and dimethyl sulfide in air using a mobile mass spectrometer with atmospheric pressure chemical ionization, combined with a fast enrichment/separation system.

    PubMed

    Kudryavtsev, Andrey S; Makas, Alexey L; Troshkov, Mikhail L; Grachev, Mikhail А; Pod'yachev, Sergey P

    2014-06-01

    A method for fast simultaneous on-site determination of methyl mercaptan and dimethyl sulfide in air was developed. The target compounds were actively collected on silica gel, followed by direct flash thermal desorption, fast separation on a short chromatographic column and detection by means of mass spectrometer with atmospheric pressure chemical ionization. During the sampling of ambient air, water vapor was removed with a Nafion selective membrane. A compact mass spectrometer prototype, which was designed earlier at Trofimuk Institute of Petroleum Geology and Geophysics, was used. The minimization of gas load of the atmospheric pressure ion source allowed reducing the power requirements and size of the vacuum system and increasing its ruggedness. The measurement cycle is about 3 min. Detection limits in a 0.6 L sample are 1 ppb for methyl mercaptan and 0.2 ppb for dimethyl sulfide. PMID:24725876

  3. Numerical simulation of heat and mass transfer processes in the nozzle and expansion unit of the separator-steam-generator system in waste-heat utilization complex

    NASA Astrophysics Data System (ADS)

    Artemov, V. I.; Minko, K. B.; Yan'kov, G. G.

    2015-12-01

    Homogeneous equilibrium and nonequilibrium (relaxation) models are used to simulate flash boiling flows in nozzles. The simulation were performed using the author's CFD-code ANES. Existing experimental data are used to test the realized mathematical model and the modified algorithms of ANES CFD-code. The results of test calculations are presented, together with data obtained for the nozzle and expansion unit of the steam generator and separator in the waste-heat system at ZAO NPVP Turbokon. The SIMPLE algorithm may be used for the transonic and supersonic flashing liquid flow. The relaxation model yields better agreement with experimental data regarding the distribution of void fraction along the nozzle axis. For the given class of flow, the difference between one- and two-dimensional models is slight.

  4. Untargeted saliva metabonomics study of breast cancer based on ultra performance liquid chromatography coupled to mass spectrometry with HILIC and RPLC separations.

    PubMed

    Zhong, Liping; Cheng, Fei; Lu, Xiaoyong; Duan, Yixiang; Wang, Xiaodong

    2016-09-01

    Breast cancer (BC) is not only the most frequently diagnosed cancer, but also the leading cause of cancer death among women worldwide. This study aimed to screen the potential salivary biomarkers for breast cancer diagnosis, staging, and biomarker discovery. For the first time, a UPLC-MS based method along with multivariate data analysis, was proposed for the global saliva metabonomics analysis and diagnosis of BC, which used both hydrophilic interaction chromatography (HILIC) and reversed-phase liquid chromatography (RPLC) separations and operated in both positive (ESI+) and negative (ESI-) ionization modes. On account of different polarities of endogenous metabolites, this method was established to overcome the boundedness of a single chromatographic approach. As a result, 18 potential metabolites for diagnosing BC were identified. A nonparametric Mann-Whitney U test, heat map, and the receiver operating characteristic (ROC) were exploited to analyze the data with the purpose of evaluating the predictive power of the 18 biomarkers. Significant differences (P<0.05) were disclosed in terms of the levels of the 18 potential biomarkers between BC patients and healthy controls (HC). Among the 18 biomarkers, three up-regulated metabolites, LysoPC (18:1), LysoPC (22:6) and MG (0:0/14:0/0:0) displayed the area under the curve (AUC) values of 0.920, 0.920 and 0.929, respectively, indicating the high accuracy of this method to predict BC. In this study, an integrated metabonomics analysis in human saliva for identifying potential biomarkers to diagnose and stage BC was successfully eastablished, which was non-invasive, reliable, low-cost, and simple. The HILIC was demonstrated to be essential for a comprehensive saliva metabonomics profiling as well as RPLC separation. This saliva metabonomics technique may provide new insight into the discovery and identification of diagnostic biomarkers for BC. PMID:27343615

  5. On-line stop-flow two-dimensional liquid chromatography-mass spectrometry method for the separation and identification of triterpenoid saponins from ginseng extract.

    PubMed

    Wang, Shuangyuan; Qiao, Lizhen; Shi, Xianzhe; Hu, Chunxiu; Kong, Hongwei; Xu, Guowang

    2015-01-01

    A method based on stop-flow two-dimensional liquid chromatography coupled with electrospray ionization mass spectrometry (2D LC-ESI MS) was established and applied to analyze triterpenoid saponins from the main root of ginseng. Due to the special structure of triterpenoid saponins (they contain polar sugar side chains and nonpolar aglycones), hydrophilic interaction chromatography (HILIC) and reversed-phase liquid chromatography (RPLC) were used for the two dimensions, respectively. A trap column was used to connect the two dimensions. The dilution effect, which is one of the main shortcomings of traditional comprehensive 2D LC methods, was largely avoided. The peak capacity of this system was 747 and the orthogonality was 56.6 %. Compared with one-dimensional HILIC or RP LC MS analysis, 257 and 185 % more mass spectral peaks (ions with intensities that were higher than 1,000) were obtained from the ginseng main root extracts, and 94 triterpenoid saponins were identified based on MS(n) information and summarized aglycone structures. Given its good linearity and repeatability, the established method was successfully applied to classify ginsengs of different ages (i.e., years of growth), and 19 triterpenoid saponins were found through statistical analysis to vary in concentration depending on the age of the ginseng. PMID:25410638

  6. Char separator

    DOEpatents

    Matthews, Francis T.

    1979-01-01

    Particulates removed from the flue gases produced in a fluidized-bed furnace are separated into high-and low-density portions. The low-density portion is predominantly char, and it is returned to the furnace or burned in a separate carbon burnup cell. The high-density portion, which is predominantly limestone products and ash, is discarded or reprocessed. According to another version, the material drained from the bed is separated, the resulting high-and low-density portions being treated in a manner similar to that in which the flue-gas particulates are treated.

  7. CENTRIFUGAL SEPARATORS

    DOEpatents

    Skarstrom, C.

    1959-03-10

    A centrifugal separator is described for separating gaseous mixtures where the temperature gradients both longitudinally and radially of the centrifuge may be controlled effectively to produce a maximum separation of the process gases flowing through. Tbe invention provides for the balancing of increases and decreases in temperature in various zones of the centrifuge chamber as the result of compression and expansions respectively, of process gases and may be employed effectively both to neutralize harmful temperature gradients and to utilize beneficial temperaturc gradients within the centrifuge.

  8. An approach to on-line electrospray mass spectrometric detection of polypeptide antibiotics of enramycin for high-speed counter-current chromatographic separation.

    PubMed

    Inoue, Koichi; Hattori, Yasuko; Hino, Tomoaki; Oka, Hisao

    2010-04-01

    In the field of pharmaceutical and biomedical analysis of peptides, a rapid on-line detection and identification for a methodology have been required for the discovery of new biological active products. In this study, a high-speed counter-current chromatography with electrospray mass spectrometry (HSCCC/ESI-MS) was developed for the on-line detection and purification of polypeptide antibiotics of enramycin-A and -B. The analytes were purified on HSCCC model CCC-1000 (multi-layer coil planet centrifuge) with a volatile solvent of two-phase system composed of n-butanol/hexane/0.05% aqueous trifluoroacetic acid solution (43/7/50, V/V/V), and detected on an LCMS-2010EV quadrupole mass spectrometer fitted with an ESI source system in positive ionization following scan mode (m/z 100-2000). The HSCCC/ESI-MS peaks indicated that enramycin-A (major m/z 786 [M+3H](3+) and minor m/z 1179 [M+2H](2+)) and enramycin-B (major m/z 791 [M+3H](3+) and minor m/z 1185 [M+2H](2+)) have the peak resolution value of 2.9 from 15mg of loaded enramycin powder. The HSCCC collected amounts of the peak fractions were additionally 4.3mg (enramycin-A), and 5.9mg (enramycin-B), respectively. These purified substances were analyzed by LC/ESI-MS with scan positive mode. Based on the LC/ESI-MS chromatograms and spectra of the fractions, enramycin-A and -B were estimated to be over 95% purity. The overall results indicate that this approach of HSCCC/ESI-MS is a powerful technique for the purification and identification of bioactive peptides. PMID:20004073

  9. Separation of intact proteins on γ-ray-induced polymethacrylate monolithic columns: A highly permeable stationary phase with high peak capacity for capillary high-performance liquid chromatography with high-resolution mass spectrometry.

    PubMed

    Simone, Patrizia; Pierri, Giuseppe; Foglia, Patrizia; Gasparrini, Francesca; Mazzoccanti, Giulia; Capriotti, Anna Laura; Ursini, Ornella; Ciogli, Alessia; Laganà, Aldo

    2016-01-01

    Polymethacrylate-based monolithic capillary columns, prepared by γ-radiation-induced polymerization, were used to optimize the experimental conditions (nature of the organic modifiers, the content of trifluoroacetic acid and the column temperature) in the separation of nine standard proteins with different hydrophobicities and a wide range of molecular weights. Because of the excellent permeability of the monolithic columns, an ion-pair reversed-phase capillary liquid chromatography with high-resolution mass spectrometry method has been developed by coupling the column directly to the mass spectrometer without a flow-split and using a standard electrospray interface. Additionally, the high working flow and concomitant high efficiency of these columns allowed us to employ a longer column (up to 50 cm) and achieve a peak capacity value superior to 1000. This work is motivated by the need to develop new materials for high-resolution chromatographic separation that combine chemical stability at elevated temperatures (up to 75°C) and a broad pH range, with a high peak capacity value. The advantage of the γ-ray-induced monolithic column lies in the batch-to-batch reproducibility and long-term high-temperature stability. Their proven high loading capacity, recovery, good selectivity and high permeability, moreover, compared well with that of a commercially available poly(styrene-divinylbenzene) monolithic column, which confirms that such monolithic supports might facilitate analysis in proteomics. PMID:26530449

  10. Stereoisomers Separation

    NASA Astrophysics Data System (ADS)

    Wieczorek, Piotr

    The use of capillary electrophoresis for enantiomer separation and optical purity determination is presented. The contents start with basic information about the nature of stereoizomers and the mechanism of enantioseparation using capillary electrophoresis techniques. The molecules to be separated show identical chemical structure and electrochemical behavior. Therefore, the chiral recognition of enantiomers is possible only by bonding to chiral selector and the separation based on very small differences in complexation energies of diastereomer complexes formed. This method is useful for this purpose due to the fact that different compounds can be used as chiral selectors. The mostly used chiral selectors like cyclodextrins, crown ethers, chiral surfactants, macrocyclic antibiotics, transition metal complexes, natural, and synthetic polymers and their application for this purpose is also discussed. Finally, examples of practical applications of electromigration techniques for enantiomers separation and determination are presented.

  11. Determination of main and minor components of silicon based materials by a combustion with elemental fluorine. Separation of gaseous fluorination products by carrier gas distillation and gas mass spectrometry

    PubMed

    Russe; Kipphardt; Broekaert

    2000-08-15

    For the determination of main and minor components in silicon-based ceramic powders, a decomposition by a combustion with elemental fluorine and separation of the volatile fluorination products by a carrier-gas distillation with a subsequent detection by quadrupole mass spectrometry is described. The necessity and success of the separation step is demonstrated for the determination of boron as a minor constituent in SiC, where the spectral interferences of silicon on the boron signals are decreased considerably. The method developed is shown to be directly applicable to determination of silicon in Si3N4, SiC, and SiO2. The determination of nitrogen in Si3N4 requires additional effort, to separate nitrogen from the excess of fluorine. For the determination of boron, a complete mobilization of BF3 is assured by the presence of an adequate amount of GeF4. Analysis results obtained with different types of calibration show a precision of 30 microg for boron at the milligram-per-gram level and a precision between 0.5 and 2% (m/m) for the main components, silicon and nitrogen. Within these standard deviations, the results agree well with the values expected from the stoichiometry, with the results for silicon and boron obtained by wet chemical decomposition and slurry techniques in combination with ICP-OES and with the results for nitrogen obtained by carrier gas heat extraction. PMID:10959976

  12. Battery separator

    SciTech Connect

    Balouskus, R.A.; Feinberg, S.C.; Lundquist, J.T.; Lundsager, C.B.

    1980-09-23

    A battery separator and a method of forming the same is described. The separator has good electrical conductivity and a high degree of inhibition to dendrite formation, and is in the form of a thin sheet formed from a substantially uniform mixture of a thermoplastic rubber and a filler in a volume ratio of from about 1:0.15 to 1:0.6. The thermoplastic rubber is preferably a styrene/elastomer/styrene block copolymer.

  13. Product separator

    DOEpatents

    Welsh, Robert A.; Deurbrouck, Albert W.

    1976-01-20

    A secondary light sensitive photoelectric product separator for use with a primary product separator that concentrates a material so that it is visually distinguishable from adjacent materials. The concentrate separation is accomplished first by feeding the material onto a vibratory inclined surface with a liquid flow, such as a wet concentrating table. Vibrations generally perpendicular to the stream direction of flow cause the concentrate to separate from its mixture according to its color. When the concentrate and its surrounding stream reach the recovery end of the table, a detecting device notes the line of color demarcation and triggers a signal if it differs from a normal condition. If no difference is noted nothing moves on the second separator. However, if a difference is detected in the constant monitoring of the color line's location, a product splitter and recovery unit normally positioned near the color line at the recovery end, moves to a new position. In this manner the selected separated concentrate is recovered at a maximum rate regardless of variations in the flow stream or other conditions present.

  14. Stability of arsenic peptides in plant extracts: off-line versus on-line parallel elemental and molecular mass spectrometric detection for liquid chromatographic separation.

    PubMed

    Bluemlein, Katharina; Raab, Andrea; Feldmann, Jörg

    2009-01-01

    The instability of metal and metalloid complexes during analytical processes has always been an issue of an uncertainty regarding their speciation in plant extracts. Two different speciation protocols were compared regarding the analysis of arsenic phytochelatin (As(III)PC) complexes in fresh plant material. As the final step for separation/detection both methods used RP-HPLC simultaneously coupled to ICP-MS and ES-MS. However, one method was the often used off-line approach using two-dimensional separation, i.e. a pre-cleaning step using size-exclusion chromatography with subsequent fraction collection and freeze-drying prior to the analysis using RP-HPLC-ICP-MS and/or ES-MS. This approach revealed that less than 2% of the total arsenic was bound to peptides such as phytochelatins in the root extract of an arsenate exposed Thunbergia alata, whereas the direct on-line method showed that 83% of arsenic was bound to peptides, mainly as As(III)PC(3) and (GS)As(III)PC(2). Key analytical factors were identified which destabilise the As(III)PCs. The low pH of the mobile phase (0.1% formic acid) using RP-HPLC-ICP-MS/ES-MS stabilises the arsenic peptide complexes in the plant extract as well as the free peptide concentration, as shown by the kinetic disintegration study of the model compound As(III)(GS)(3) at pH 2.2 and 3.8. But only short half-lives of only a few hours were determined for the arsenic glutathione complex. Although As(III)PC(3) showed a ten times higher half-life (23 h) in a plant extract, the pre-cleaning step with subsequent fractionation in a mobile phase of pH 5.6 contributes to the destabilisation of the arsenic peptides in the off-line method. Furthermore, it was found that during a freeze-drying process more than 90% of an As(III)PC(3) complex and smaller free peptides such as PC(2) and PC(3) can be lost. Although the two-dimensional off-line method has been used successfully for other metal complexes, it is concluded here that the fractionation and

  15. Geologic interpretations of seismic data Route 128 (Northern Circumferential Highway) cut, and Hopkins Street grade separation stations 1-18 in Wakefield, Mass.

    USGS Publications Warehouse

    May, James E.; Lineham, Rev. Daniel

    1950-01-01

    The completion of a segment of the Northern Circumferential Highway, Route 126, in Wakefield, Mass., requires an underpass bridge at Hopkins Street, Station 5+50. The plan of the project shows approximately 1800 feet if approach cuts between stations 1 and 18. In October 1945 a preliminary seismic study was made of a segment of this cut between stations 6+50 and 13+30. Four profiles were made at this time and a report was submitted by Newton E. Chute and Rev. Daniel Linhan (file report of January 15). This work showed a relatively shallow (in general, 6 to 12 feet in depth) somewhat irregular bedrock surface between stations 6+50 and 13+50. That data indicated that much of this segment of the cut will be in bedrock. In order to obtain more complete data for the preparation of detailed estimates on the amount of bedrock to be excavated for this segment of the cut, and also to obtain sufficient data for the unexplored segment of the cut, 21 additional seismic traverses were made in September 1949. The present report contains only the results obtained from this later work. The work was performed as a part of a cooperative program of the Massachusetts Department of Public Works and the United States Geological Survey.

  16. Selective separation and characterization of the stress degradation products of ondansetron hydrochloride by liquid chromatography with quadrupole time-of-flight mass spectrometry.

    PubMed

    Talluri, Murali V N Kumar; Keshari, Kundan Kumar; Kalariya, Pradipbhai D; Srinivas, Ragampeta

    2015-05-01

    Ondansetron hydrochloride was subjected to forced degradation studies under various conditions of hydrolysis (acidic, basic, and neutral), oxidation, photolysis, and thermal as prescribed by International Conference on Harmonisation guideline Q1A (R2). A simple, selective, precise, and accurate high-performance liquid chromatography method was developed on a Waters Xterra C18 (150 × 4.6 mm id, 3.5 μm) column using 10 mM ammonium formate (pH 3.0)/methanol as a mobile phase in gradient elution mode at a flow rate of 0.6 mL/min. The method was extended to liquid chromatography quadrupole time-of-flight tandem mass spectrometry for identification and structural characterization of stress degradation products of ondansetron. The drug showed significant degradation in base hydrolytic and photolytic stress conditions in the liquid state, while it was found to be stable in neutral, acidic, thermal, and oxidative stress conditions. A total of five degradation products were characterized and most probable mechanisms for the formation of degradation products have been proposed on the basis of a comparison of the fragmentation of the [M + H](+) ions of the drug and its degradation products. Finally, the developed method was validated in terms of specificity, linearity, accuracy, precision, and robustness as per International Conference on Harmonisation guideline Q2 (R1). PMID:25727389

  17. Subaru and e-Merlin observations of NGC 3718. Diaries of a supermassive black hole recoil?

    NASA Astrophysics Data System (ADS)

    Markakis, K.; Dierkes, J.; Eckart, A.; Nishiyama, S.; Britzen, S.; García-Marín, M.; Horrobin, M.; Muxlow, T.; Zensus, J. A.

    2015-08-01

    NGC 3718 is a low-ionization nuclear emission line region (LINER) L1.9 galaxy, lying at a distance of about ~17.4 Mpc from the Earth; its similarities with NGC 5128 often award it the name northern Centaurus A. The presence of a compact radio source with a candidate jet structure, a prominent dust lane, and a strongly warped molecular and atomic gas disk are indications that NGC 3718 has undergone some sort of a large-scale gravitational interaction sometime in the recent past, which channeled gas towards the center, feeding the black hole and igniting the central engine. One proposed scenario involves an encounter with the close neighboring galaxy NGC 3729, while other authors favor a merging event with mass ratio ≥(3-4):1 as the origin of NGC3718. We use high angular resolution (~100 mas) e-Merlin radio and Subaru near-IR (NIR) (~170 mas) data to take a detailed view of the processes taking place in its central region. In order to preserve some objectivity in our interpretation, we combine our results with literature values and findings from previous studies. Our NIR maps suggest, on the one hand, that towards the stellar bulge there are no large-scale absorption phenomena caused by the apparent dust lane and, on the other, that there is a significant (local) contribution from hot (~1000 K) dust to the nuclear NIR emission. The position where this takes place appears to be closer to the offset compact radio emission from our e-Merlin 6 cm map and is offset by ~4.25 pc from the center of the underlying stellar bulge. The shape of the radio map suggests the presence of one (or possibly two, forming an X-shape) bipolar structure(s) ~1 (~0.6) arcsec across, which combined with the balance between the gas and the stellar velocity dispersions and the presence of hard X-ray emission, point towards effects expected by AGN feedback. We also argue that NGC 3718 has a core in its surface brightness profile, although it is a gas-rich galaxy and we discuss its mixed

  18. Post-polymerization photografting on methacrylate-based monoliths for separation of intact proteins and protein digests with comprehensive two-dimensional liquid chromatography hyphenated with high-resolution mass spectrometry.

    PubMed

    Vonk, Rudy J; Wouters, Sam; Barcaru, Andrei; Vivó-Truyols, Gabriel; Eeltink, Sebastiaan; de Koning, Leo J; Schoenmakers, Peter J

    2015-05-01

    Post-polymerization photografting is a versatile tool to alter the surface chemistry of organic-based monoliths so as to obtain desired stationary phase properties. In this study, 2-acrylamido-2-methyl-1-propanesulfonic acid was grafted to a hydrophobic poly(butyl methacrylate-co-ethylene glycol dimethacrylate) monolith to create a strong cation exchange stationary phase. Both single-step and two-step photografting were addressed, and the effects of grafting conditions were assessed. An experimental design has been applied in an attempt to optimize three of the key parameters of the two-step photografting chemistry, i.e. the grafting time of the initiator, the monomer concentration and the monomer irradiation time. The photografted columns were implemented in a comprehensive two-dimensional column liquid chromatography ( (t) LC ×  (t) LC) workflow and applied for the separation of intact proteins and peptides. A baseline separation of 11 intact proteins was obtained within 20 min by implementing a gradient across a limited RP composition window in the second dimension. (t) LC ×  (t) LC with UV detection was used for the separation of cytochrome c digest, bovine serum insulin digest and a digest of a complex protein mixture. A semi-quantitative estimation of the occupation of separation space, the orthogonality, of the (t) LC ×  (t) LC system yielded 75%. The (t) LC ×  (t) LC setup was hyphenated to a high-resolution Fourier transform ion cyclotron resonance mass spectrometer instrument to identify the bovine serum insulin tryptic peptides and to demonstrate the compatibility with MS analysis. PMID:25801383

  19. Map Separates

    USGS Publications Warehouse

    U.S. Geological Survey

    2001-01-01

    U.S. Geological Survey (USGS) topographic maps are printed using up to six colors (black, blue, green, red, brown, and purple). To prepare your own maps or artwork based on maps, you can order separate black-and-white film positives or negatives for any color printed on a USGS topographic map, or for one or more of the groups of related features printed in the same color on the map (such as drainage and drainage names from the blue plate.) In this document, examples are shown with appropriate ink color to illustrate the various separates. When purchased, separates are black-and-white film negatives or positives. After you receive a film separate or composite from the USGS, you can crop, enlarge or reduce, and edit to add or remove details to suit your special needs. For example, you can adapt the separates for making regional and local planning maps or for doing many kinds of studies or promotions by using the features you select and then printing them in colors of your choice.

  20. Measurement and calculation of recoil pressure produced during CO{sub 2} laser interaction with ice

    SciTech Connect

    Semak, V.V.; Knorovsky, G.A.; Maccallum, D.O.; Noble, D.R.; Kanouff, M.P.

    1999-12-09

    Evaporation is a classical physics problem which, because of its significant importance for many engineering applications, has drawn considerable attention by previous researchers. Classical theoretical models [Ta. I. Frenkel, Kinetic Theory of Liquids, Clarendon Press, Oxford, 1946] represent evaporation in a simplistic way as the escape of atoms with highest velocities from a potential well with the depth determined by the atomic binding energy. The processes taking place in the gas phase above the rapidly evaporating surface have also been studied in great detail [S.I.Anisimov and V. A. Khokhlov, Instabilities in Lasser-Matter Interaction, CRC Press, Boca Raton, 1995]. The description of evaporation utilizing these models is known to adequately characterize drilling with high beam intensity, e.g., >10{sup 7} W/cm{sup 2}. However, the interaction regimes when beam intensity is relatively low, such as during welding or cutting, lack both theoretical and experimental consideration of the evaporation. It was shown recently that if the evaporation is treated in accordance with Anisimov et.al.'s approach, then predicted evaporation recoil should be a substantial factor influencing melt flow and related heat transfer during laser beam welding and cutting. To verify the applicability of this model for low beam intensity interaction, the authors compared the results of measurements and calculations of recoil pressure generated during laser beam irradiation of a target. The target material used was water ice at {minus}10 C. The displacement of a target supported in a nearly frictionless air bearing under irradiation by a defocused laser beam from a 14 kW CO{sub 2} laser was recorded and Newton's laws of motion used to derive the recoil pressure.