Sample records for requirements doe order

  1. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY BONDING OF SHIP'S PERSONNEL Section 1 What this order does. This order requires that General Agents, appointed under Service...

  2. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY BONDING OF SHIP'S PERSONNEL Section 1 What this order does. This order requires that General Agents, appointed under Service...

  3. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY BONDING OF SHIP'S PERSONNEL Section 1 What this order does. This order requires that General Agents, appointed under Service...

  4. DOE orders : materials packaging and transportation procedures

    DOT National Transportation Integrated Search

    1995-09-27

    The Orders listed below are canceled. Cancellation of an Order : does not, by itself, modify or otherwise affect any contractual obligation to : comply with such an Order. Requirements in the canceled Orders which are : incorporated by reference in a...

  5. Fluor Daniel Hanford implementation plan for DOE Order 5480.28, Natural phenomena hazards mitigation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Conrads, T.J.

    1997-09-12

    Natural phenomena hazards (NPH) are unexpected acts of nature that pose a threat or danger to workers, the public, or the environment. Earthquakes, extreme winds (hurricane and tornado), snow, flooding, volcanic ashfall, and lightning strikes are examples of NPH that could occur at the Hanford Site. U.S. Department of Energy (DOE) policy requires facilities to be designed, constructed, and operated in a manner that protects workers, the public, and the environment from hazards caused by natural phenomena. DOE Order 5480.28, Natural Phenomena Hazards Mitigation, includes rigorous new natural phenomena criteria for the design of new DOE facilities, as well asmore » for the evaluation and, if necessary, upgrade of existing DOE facilities. The Order was transmitted to Westinghouse Hanford Company in 1993 for compliance and is also identified in the Project Hanford Management Contract, Section J, Appendix C. Criteria and requirements of DOE Order 5480.28 are included in five standards, the last of which, DOE-STD-1023, was released in fiscal year 1996. Because the Order was released before all of its required standards were released, enforcement of the Order was waived pending release of the last standard and determination of an in-force date by DOE Richland Operations Office (DOE-RL). Agreement also was reached between the Management and Operations Contractor and DOE-RL that the Order would become enforceable for new structures, systems, and components (SSCS) 60 days following issue of a new order-based design criteria in HNF-PRO-97, Engineering Design and Evaluation. The order also requires that commitments addressing existing SSCs be included in an implementation plan that is to be issued 1 year following the release of the last standard. Subsequently, WHC-SP-1175, Westinghouse Hanford Company Implementation Plan for DOE Order 5480.28, Natural Phenomena Hazards Mitigation, Rev. 0, was issued in November 1996, and this document, HNF-SP-1175, Fluor Daniel Hanford

  6. Policy Perspective: Meeting the Challenge of the DOE Order 436.1 Departmental Sustainability - 12527

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    MacDonald, Jennifer C.

    2012-07-01

    DOE's Sustainability Performance Office is working to meet sustainability goals at DOE by implementing Executive Orders, Departmental policy, the DOE Strategic Sustainability Performance Plan (SSPP) and legislation related to sustainability. Through implementation of Executive Orders, Departmental policy, the SSPP, statutory requirements and regular reporting, analysis and communication, DOE's SPO is working to maintain and expand DOE's leadership in sustainability. (authors)

  7. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY PROCEDURE TO BE... NSA ORDER NO. 47 Section 1 What this order does. This order prescribes procedures for the preparation...

  8. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY PROCEDURE TO BE... NSA ORDER NO. 47 Section 1 What this order does. This order prescribes procedures for the preparation...

  9. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY PROCEDURE TO BE... NSA ORDER NO. 47 Section 1 What this order does. This order prescribes procedures for the preparation...

  10. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY AUTHORITY AND... AGREEMENT Section 1 What this order does. This order outlines General Agents' limited authority to arrange...

  11. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY LAUNCH SERVICES Section 1 What this order does. This order prescribes the circumstances under which launch hire will be...

  12. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY GENERAL AGENT'S RESPONSIBILITY IN CONNECTION WITH FOREIGN REPAIR CUSTOM'S ENTRIES Section 1 What this order does. This order...

  13. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY AUTHORITY AND... AGREEMENT Section 1 What this order does. This order outlines General Agents' limited authority to arrange...

  14. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY LAUNCH SERVICES Section 1 What this order does. This order prescribes the circumstances under which launch hire will be...

  15. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY AUTHORITY AND... AGREEMENT Section 1 What this order does. This order outlines General Agents' limited authority to arrange...

  16. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY GENERAL AGENT'S RESPONSIBILITY IN CONNECTION WITH FOREIGN REPAIR CUSTOM'S ENTRIES Section 1 What this order does. This order...

  17. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY LAUNCH SERVICES Section 1 What this order does. This order prescribes the circumstances under which launch hire will be...

  18. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY GENERAL AGENT'S RESPONSIBILITY IN CONNECTION WITH FOREIGN REPAIR CUSTOM'S ENTRIES Section 1 What this order does. This order...

  19. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY REPATRIATION OF SEAMEN Section 1 What this order does. This order prescribes the manner in which seamen separated from vessels...

  20. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY REPATRIATION OF SEAMEN Section 1 What this order does. This order prescribes the manner in which seamen separated from vessels...

  1. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY REPATRIATION OF SEAMEN Section 1 What this order does. This order prescribes the manner in which seamen separated from vessels...

  2. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY VOYAGE DATA Section 1 What this order does. The General Agents, as appointed by the National Shipping Authority, promulgated...

  3. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY VOYAGE DATA Section 1 What this order does. The General Agents, as appointed by the National Shipping Authority, promulgated...

  4. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY VOYAGE DATA Section 1 What this order does. The General Agents, as appointed by the National Shipping Authority, promulgated...

  5. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY AUTHORITY AND RESPONSIBILITY OF GENERAL AGENTS TO UNDERTAKE EMERGENCY REPAIRS IN FOREIGN PORTS Section 1 What this order does...

  6. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY AUTHORITY AND RESPONSIBILITY OF GENERAL AGENTS TO UNDERTAKE EMERGENCY REPAIRS IN FOREIGN PORTS Section 1 What this order does...

  7. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY AUTHORITY AND RESPONSIBILITY OF GENERAL AGENTS TO UNDERTAKE EMERGENCY REPAIRS IN FOREIGN PORTS Section 1 What this order does...

  8. Report on inspection of compliance with DOE Order 2030.4B at the Savannah River Site

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1997-03-01

    The purpose of this inspection was to evaluate contractor compliance at the Savannah River Site (SRS) with Department of Energy (DOE) Order 2030.4B, {open_quotes}Reporting Fraud, Waste, And Abuse To The Office Of Inspector General.{close_quotes} The specific objective was to determine if the SRS management and operating (M&O) contractors were complying with the requirements in Paragraph 6.c. of DOE Order 2030.4B. These requirements are: (1) annual notification to employees of their duty to report allegations of fraud, waste, abuse, corruption, or mismanagement; (2) display and publish the DOE Office of Inspector General (OIG) Hotline telephone number in common areas of buildings;more » (3) display and publish the DOE OIG Hotline number in telephone books and newsletters; and (4) notify the OIG cases referred to other law enforcement entities.« less

  9. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY SLOP CHESTS Section 1 What this order does. In accordance with the provisions of section 11 f the act of Congress approved...

  10. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY SLOP CHESTS Section 1 What this order does. In accordance with the provisions of section 11 f the act of Congress approved...

  11. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false What this order does. Section 1 Section 1 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY SLOP CHESTS Section 1 What this order does. In accordance with the provisions of section 11 f the act of Congress approved...

  12. Hazardous Substance Release Reporting Under CERCLA, EPCR {section}304 and DOE Emergency Management System (EMS) and DOE Occurrence Reporting Requirements. Environmental Guidance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Traceski, T.T.

    1994-06-01

    Releases of various substances from DOE facilities may be subject to reporting requirements under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) and the Emergency Planning and Community Right-to-Know Act (EPCRA), as well as DOE`s internal ``Occurrence Reporting and Processing of Operations Information`` and the ``Emergency Management System`` (EMS). CERCLA and EPCPA are Federal laws that require immediate reporting of a release of a Hazardous Substance (HS) and an Extremely Hazardous Substance (EHS), respectively, in a Reportable Quantity (RQ) or more within a 24-hour period. This guidance uses a flowchart, supplemental information, and tables to provide an overview ofmore » the process to be followed, and more detailed explanations of the actions that must be performed, when chemical releases of HSs, EHSs, pollutants, or contaminants occur at DOE facilities. This guidance should be used in conjunction with, rather than in lieu of, applicable laws, regulations, and DOE Orders. Relevant laws, regulations, and DOE Orders are referenced throughout this guidance.« less

  13. Assessment of documentation requirements under DOE 5481. 1, Safety Analysis and Review System (SARS)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Browne, E.T.

    1981-03-01

    This report assesses the requirements of DOE Order 5481.1, Safety Analysis and Review System for DOE Operations (SARS) in regard to maintaining SARS documentation. Under SARS, all pertinent details of the entire safety analysis and review process for each DOE operation are to be traceable from the initial identification of a hazard. This report is intended to provide assistance in identifying the points in the SARS cycle at which documentation is required, what type of documentation is most appropriate, and where it ultimately should be maintained.

  14. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ACCOMPLISHMENT OF SHIP REPAIRS UNDER NATIONAL SHIPPING AUTHORITY INDIVIDUAL CONTRACT FOR MINOR REPAIRS-NSA-WORKSMALREP Section 1 What this order does. This order authorizes the use of NSA-WORKSMALREP individual...

  15. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ACCOMPLISHMENT OF SHIP REPAIRS UNDER NATIONAL SHIPPING AUTHORITY INDIVIDUAL CONTRACT FOR MINOR REPAIRS-NSA-WORKSMALREP Section 1 What this order does. This order authorizes the use of NSA-WORKSMALREP individual...

  16. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ACCOMPLISHMENT OF SHIP REPAIRS UNDER NATIONAL SHIPPING AUTHORITY INDIVIDUAL CONTRACT FOR MINOR REPAIRS-NSA-WORKSMALREP Section 1 What this order does. This order authorizes the use of NSA-WORKSMALREP individual...

  17. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ACCOMPLISHMENT OF SHIP REPAIRS UNDER NATIONAL SHIPPING AUTHORITY INDIVIDUAL CONTRACT FOR MINOR REPAIRS-NSA-WORKSMALREP Section 1 What this order does. This order authorizes the use of NSA-WORKSMALREP individual...

  18. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ACCOMPLISHMENT OF SHIP REPAIRS UNDER NATIONAL SHIPPING AUTHORITY INDIVIDUAL CONTRACT FOR MINOR REPAIRS-NSA-WORKSMALREP Section 1 What this order does. This order authorizes the use of NSA-WORKSMALREP individual...

  19. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ACCOMPLISHMENT OF VESSEL REPAIRS UNDER NATIONAL SHIPPING AUTHORITY MASTER LUMP SUM REPAIR CONTRACT-NSA-LUMPSUMREP Section 1 What this order does. This order cancels NSA Order No. 32 (SRM-1); and outlines the procedure to... repairs under the National Shipping Authority Master Repair Contract, NSA-LUMPSUMREP. The Coast Directors...

  20. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ACCOMPLISHMENT OF VESSEL REPAIRS UNDER NATIONAL SHIPPING AUTHORITY MASTER LUMP SUM REPAIR CONTRACT-NSA-LUMPSUMREP Section 1 What this order does. This order cancels NSA Order No. 32 (SRM-1); and outlines the procedure to... repairs under the National Shipping Authority Master Repair Contract, NSA-LUMPSUMREP. The Coast Directors...

  1. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ACCOMPLISHMENT OF VESSEL REPAIRS UNDER NATIONAL SHIPPING AUTHORITY MASTER LUMP SUM REPAIR CONTRACT-NSA-LUMPSUMREP Section 1 What this order does. This order cancels NSA Order No. 32 (SRM-1); and outlines the procedure to... repairs under the National Shipping Authority Master Repair Contract, NSA-LUMPSUMREP. The Coast Directors...

  2. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ACCOMPLISHMENT OF VESSEL REPAIRS UNDER NATIONAL SHIPPING AUTHORITY MASTER LUMP SUM REPAIR CONTRACT-NSA-LUMPSUMREP Section 1 What this order does. This order cancels NSA Order No. 32 (SRM-1); and outlines the procedure to... repairs under the National Shipping Authority Master Repair Contract, NSA-LUMPSUMREP. The Coast Directors...

  3. 46 CFR Section 1 - What this order does.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ACCOMPLISHMENT OF VESSEL REPAIRS UNDER NATIONAL SHIPPING AUTHORITY MASTER LUMP SUM REPAIR CONTRACT-NSA-LUMPSUMREP Section 1 What this order does. This order cancels NSA Order No. 32 (SRM-1); and outlines the procedure to... repairs under the National Shipping Authority Master Repair Contract, NSA-LUMPSUMREP. The Coast Directors...

  4. 20 CFR 639.2 - What does WARN require?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false What does WARN require? 639.2 Section 639.2 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR WORKER ADJUSTMENT AND RETRAINING NOTIFICATION § 639.2 What does WARN require? WARN requires employers who are planning a plant...

  5. 13 CFR 124.1011 - What format, degree of specificity, and basis does SBA require to consider an SDB protest?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., and basis does SBA require to consider an SDB protest? 124.1011 Section 124.1011 Business Credit and... § 124.1011 What format, degree of specificity, and basis does SBA require to consider an SDB protest? (a) Format. An SDB protest need not be in any specific format in order for SBA to consider it. (b...

  6. 13 CFR 124.1011 - What format, degree of specificity, and basis does SBA require to consider an SDB protest?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., and basis does SBA require to consider an SDB protest? 124.1011 Section 124.1011 Business Credit and... § 124.1011 What format, degree of specificity, and basis does SBA require to consider an SDB protest? (a) Format. An SDB protest need not be in any specific format in order for SBA to consider it. (b...

  7. 13 CFR 124.1011 - What format, degree of specificity, and basis does SBA require to consider an SDB protest?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., and basis does SBA require to consider an SDB protest? 124.1011 Section 124.1011 Business Credit and... § 124.1011 What format, degree of specificity, and basis does SBA require to consider an SDB protest? (a) Format. An SDB protest need not be in any specific format in order for SBA to consider it. (b...

  8. 13 CFR 124.1011 - What format, degree of specificity, and basis does SBA require to consider an SDB protest?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., and basis does SBA require to consider an SDB protest? 124.1011 Section 124.1011 Business Credit and... § 124.1011 What format, degree of specificity, and basis does SBA require to consider an SDB protest? (a) Format. An SDB protest need not be in any specific format in order for SBA to consider it. (b...

  9. 13 CFR 124.1011 - What format, degree of specificity, and basis does SBA require to consider an SDB protest?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., and basis does SBA require to consider an SDB protest? 124.1011 Section 124.1011 Business Credit and... § 124.1011 What format, degree of specificity, and basis does SBA require to consider an SDB protest? (a) Format. An SDB protest need not be in any specific format in order for SBA to consider it. (b...

  10. A conceptual framework for using DOE 5700.6C and the other DOE orders as an integrated management system; the Fermilab experience

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bodnarczuk, M.

    In this paper, I describe a conceptual framework that uses DOE Order 5700.6C and more than 140 other DOE Orders as an integrated management system -- but I describe it within the context of the broader sociological and cultural issues of doing research at DOE funded facilities. The conceptual framework has two components. The first involves an interpretation of the 10 criteria of DOE 5700.6C that is tailored for a research environment. The second component involves using the 10 criteria as functional categories that orchestrate and integrate the other DOE Orders into a total management system. The Fermilab approach aimsmore » at reducing (or eliminating) the redundancy and overlap within the DOE Orders system at the contractor level.« less

  11. A conceptual framework for using DOE 5700. 6C and the other DOE orders as an integrated management system; the Fermilab experience

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bodnarczuk, M.

    In this paper, I describe a conceptual framework that uses DOE Order 5700.6C and more than 140 other DOE Orders as an integrated management system -- but I describe it within the context of the broader sociological and cultural issues of doing research at DOE funded facilities. The conceptual framework has two components. The first involves an interpretation of the 10 criteria of DOE 5700.6C that is tailored for a research environment. The second component involves using the 10 criteria as functional categories that orchestrate and integrate the other DOE Orders into a total management system. The Fermilab approach aimsmore » at reducing (or eliminating) the redundancy and overlap within the DOE Orders system at the contractor level.« less

  12. Proposed Risk-Informed Seismic Hazard Periodic Reevaluation Methodology for Complying with DOE Order 420.1C

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kammerer, Annie

    Department of Energy (DOE) nuclear facilities must comply with DOE Order 420.1C Facility Safety, which requires that all such facilities review their natural phenomena hazards (NPH) assessments no less frequently than every ten years. The Order points the reader to Standard DOE-STD-1020-2012. In addition to providing a discussion of the applicable evaluation criteria, the Standard references other documents, including ANSI/ANS-2.29-2008 and NUREG-2117. These documents provide supporting criteria and approaches for evaluating the need to update an existing probabilistic seismic hazard analysis (PSHA). All of the documents are consistent at a high level regarding the general conceptual criteria that should bemore » considered. However, none of the documents provides step-by-step detailed guidance on the required or recommended approach for evaluating the significance of new information and determining whether or not an existing PSHA should be updated. Further, all of the conceptual approaches and criteria given in these documents deal with changes that may have occurred in the knowledge base that might impact the inputs to the PSHA, the calculated hazard itself, or the technical basis for the hazard inputs. Given that the DOE Order is aimed at achieving and assuring the safety of nuclear facilities—which is a function not only of the level of the seismic hazard but also the capacity of the facility to withstand vibratory ground motions—the inclusion of risk information in the evaluation process would appear to be both prudent and in line with the objectives of the Order. The purpose of this white paper is to describe a risk-informed methodology for evaluating the need for an update of an existing PSHA consistent with the DOE Order. While the development of the proposed methodology was undertaken as a result of assessments for specific SDC-3 facilities at Idaho National Laboratory (INL), and it is expected that the application at INL will provide a demonstration

  13. Proposed Risk-Informed Seismic Hazard Periodic Reevaluation Methodology for Complying with DOE Order 420.1C

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kammerer, Annie

    Department of Energy (DOE) nuclear facilities must comply with DOE Order 420.1C Facility Safety, which requires that all such facilities review their natural phenomena hazards (NPH) assessments no less frequently than every ten years. The Order points the reader to Standard DOE-STD-1020-2012. In addition to providing a discussion of the applicable evaluation criteria, the Standard references other documents, including ANSI/ANS-2.29-2008 and NUREG-2117. These documents provide supporting criteria and approaches for evaluating the need to update an existing probabilistic seismic hazard analysis (PSHA). All of the documents are consistent at a high level regarding the general conceptual criteria that should bemore » considered. However, none of the documents provides step-by-step detailed guidance on the required or recommended approach for evaluating the significance of new information and determining whether or not an existing PSHA should be updated. Further, all of the conceptual approaches and criteria given in these documents deal with changes that may have occurred in the knowledge base that might impact the inputs to the PSHA, the calculated hazard itself, or the technical basis for the hazard inputs. Given that the DOE Order is aimed at achieving and assuring the safety of nuclear facilities—which is a function not only of the level of the seismic hazard but also the capacity of the facility to withstand vibratory ground motions—the inclusion of risk information in the evaluation process would appear to be both prudent and in line with the objectives of the Order. The purpose of this white paper is to describe a risk-informed methodology for evaluating the need for an update of an existing PSHA consistent with the DOE Order. While the development of the proposed methodology was undertaken as a result of assessments for specific SDC-3 facilities at Idaho National Laboratory (INL), and it is expected that the application at INL will provide a demonstration

  14. 21 CFR 1.378 - What criteria does FDA use to order a detention?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false What criteria does FDA use to order a detention? 1... General Provisions § 1.378 What criteria does FDA use to order a detention? An officer or qualified employee of FDA may order the detention of any article of food that is found during an inspection...

  15. 21 CFR 1.378 - What criteria does FDA use to order a detention?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false What criteria does FDA use to order a detention? 1... General Provisions § 1.378 What criteria does FDA use to order a detention? An officer or qualified employee of FDA may order the detention of any article of food that is found during an inspection...

  16. 21 CFR 1.378 - What criteria does FDA use to order a detention?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false What criteria does FDA use to order a detention? 1... General Provisions § 1.378 What criteria does FDA use to order a detention? An officer or qualified employee of FDA may order the detention of any article of food that is found during an inspection...

  17. 21 CFR 1.378 - What criteria does FDA use to order a detention?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false What criteria does FDA use to order a detention? 1... General Provisions § 1.378 What criteria does FDA use to order a detention? An officer or qualified employee of FDA may order the detention of any article of food that is found during an inspection...

  18. 21 CFR 1.378 - What criteria does FDA use to order a detention?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false What criteria does FDA use to order a detention? 1... General Provisions § 1.378 What criteria does FDA use to order a detention? An officer or qualified employee of FDA may order the detention of any article of food that is found during an inspection...

  19. 40 CFR 35.4170 - What kinds of reporting does EPA require?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false What kinds of reporting does EPA require? 35.4170 Section 35.4170 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND... § 35.4170 What kinds of reporting does EPA require? There are several types of reports you need to...

  20. 28 CFR 0.181 - Requirements for orders.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the Attorney General § 0.181 Requirements for orders. Each order prepared for issuance by or approval of the Attorney General shall be given a suitable title, shall contain a clear and concise statement...

  1. Quality assurance grading guidelines for research and development at DOE facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Powell, T.B.; Morris, R.N.

    1993-01-01

    The quality assurance (QA) requirements for the US Department of Energy (DOE) are established in DOE Order 5700.6C. This order is applicable for all DOE departmental elements, management, and maintenance and operating contractors and requires that documented Quality Assurance Programs (QAPs) are prepared at all levels; it has one attachment. The DOE Office of Energy Research (DOE-ER) has issued a standard to ensure implementation of the full intent of this order in the ER community.

  2. 34 CFR 462.13 - What criteria and requirements does the Secretary use for determining the suitability of tests?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... for determining the suitability of tests? 462.13 Section 462.13 Education Regulations of the Offices... the Secretary Use To Review the Suitability of Tests for Use in the NRS? § 462.13 What criteria and requirements does the Secretary use for determining the suitability of tests? In order for the Secretary to...

  3. 34 CFR 462.13 - What criteria and requirements does the Secretary use for determining the suitability of tests?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... for determining the suitability of tests? 462.13 Section 462.13 Education Regulations of the Offices... the Secretary Use To Review the Suitability of Tests for Use in the NRS? § 462.13 What criteria and requirements does the Secretary use for determining the suitability of tests? In order for the Secretary to...

  4. 34 CFR 462.13 - What criteria and requirements does the Secretary use for determining the suitability of tests?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... for determining the suitability of tests? 462.13 Section 462.13 Education Regulations of the Offices... the Secretary Use To Review the Suitability of Tests for Use in the NRS? § 462.13 What criteria and requirements does the Secretary use for determining the suitability of tests? In order for the Secretary to...

  5. 34 CFR 462.13 - What criteria and requirements does the Secretary use for determining the suitability of tests?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... for determining the suitability of tests? 462.13 Section 462.13 Education Regulations of the Offices... the Secretary Use To Review the Suitability of Tests for Use in the NRS? § 462.13 What criteria and requirements does the Secretary use for determining the suitability of tests? In order for the Secretary to...

  6. 25 CFR 42.6 - When does due process require a formal disciplinary hearing?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false When does due process require a formal disciplinary... RIGHTS § 42.6 When does due process require a formal disciplinary hearing? Unless local school policies and procedures provide for less, a formal disciplinary hearing is required before a suspension in...

  7. 40 CFR 33.301 - What does this subpart require?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... AGENCY PROGRAMS Good Faith Efforts § 33.301 What does this subpart require? A recipient, including one... good faith efforts whenever procuring construction, equipment, services and supplies under an EPA...

  8. 40 CFR 33.301 - What does this subpart require?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... AGENCY PROGRAMS Good Faith Efforts § 33.301 What does this subpart require? A recipient, including one... good faith efforts whenever procuring construction, equipment, services and supplies under an EPA...

  9. 40 CFR 33.301 - What does this subpart require?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... AGENCY PROGRAMS Good Faith Efforts § 33.301 What does this subpart require? A recipient, including one... good faith efforts whenever procuring construction, equipment, services and supplies under an EPA...

  10. 40 CFR 33.301 - What does this subpart require?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... AGENCY PROGRAMS Good Faith Efforts § 33.301 What does this subpart require? A recipient, including one... good faith efforts whenever procuring construction, equipment, services and supplies under an EPA...

  11. 20 CFR 639.2 - What does WARN require?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What does WARN require? 639.2 Section 639.2 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR WORKER ADJUSTMENT AND... closing or a mass layoff to give affected employees at least 60 days' notice of such an employment action...

  12. 20 CFR 653.501 - Requirements for accepting and processing clearance orders.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...: (1) The job order does not contain an unlawful discriminatory specification by race, color, religion... time needed to return home for the beginning of the school year; (xi) An assurance that no extension of...

  13. 20 CFR 653.501 - Requirements for accepting and processing clearance orders.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...: (1) The job order does not contain an unlawful discriminatory specification by race, color, religion... time needed to return home for the beginning of the school year; (xi) An assurance that no extension of...

  14. 20 CFR 653.501 - Requirements for accepting and processing clearance orders.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...: (1) The job order does not contain an unlawful discriminatory specification by race, color, religion... time needed to return home for the beginning of the school year; (xi) An assurance that no extension of...

  15. Simulation Higher Order Language Requirements Study.

    ERIC Educational Resources Information Center

    Goodenough, John B.; Braun, Christine L.

    The definitions provided for high order language (HOL) requirements for programming flight training simulators are based on the analysis of programs written for a variety of simulators. Examples drawn from these programs are used to justify the need for certain HOL capabilities. A description of the general structure and organization of the…

  16. 10 CFR 490.602 - Special orders.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 3 2013-01-01 2013-01-01 false Special orders. 490.602 Section 490.602 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Investigations and Enforcement § 490.602 Special orders. (a) DOE may require by general or special orders that any person— (1) File, in...

  17. 10 CFR 490.602 - Special orders.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 3 2012-01-01 2012-01-01 false Special orders. 490.602 Section 490.602 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Investigations and Enforcement § 490.602 Special orders. (a) DOE may require by general or special orders that any person— (1) File, in...

  18. 10 CFR 490.602 - Special orders.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 3 2014-01-01 2014-01-01 false Special orders. 490.602 Section 490.602 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Investigations and Enforcement § 490.602 Special orders. (a) DOE may require by general or special orders that any person— (1) File, in...

  19. 10 CFR 490.602 - Special orders.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Special orders. 490.602 Section 490.602 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Investigations and Enforcement § 490.602 Special orders. (a) DOE may require by general or special orders that any person— (1) File, in...

  20. 10 CFR 490.602 - Special orders.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Special orders. 490.602 Section 490.602 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Investigations and Enforcement § 490.602 Special orders. (a) DOE may require by general or special orders that any person— (1) File, in...

  1. 41 CFR 102-3.185 - What does this subpart require agencies to do?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... National Academy of Sciences or the National Academy of Public Administration? § 102-3.185 What does this... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What does this subpart require agencies to do? 102-3.185 Section 102-3.185 Public Contracts and Property Management Federal...

  2. 43 CFR 3602.14 - What kind of financial security does BLM require?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... DISPOSAL Mineral Materials Sales Applications § 3602.14 What kind of financial security does BLM require? (a) For contracts of $2,000 or more, BLM will require a performance bond of an amount sufficient to meet the reclamation standards provided for in the contract, but at least $500. If you have a sales...

  3. 43 CFR 3216.14 - What filing fees and forms does a transfer require?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... for three leases, submit three times the fee for “Assignment and transfer of record title or operating... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false What filing fees and forms does a transfer... LEASING Transfers § 3216.14 What filing fees and forms does a transfer require? With each transfer request...

  4. 43 CFR 3216.14 - What filing fees and forms does a transfer require?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... for three leases, submit three times the fee for “Assignment and transfer of record title or operating... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false What filing fees and forms does a transfer... LEASING Transfers § 3216.14 What filing fees and forms does a transfer require? With each transfer request...

  5. 43 CFR 3216.14 - What filing fees and forms does a transfer require?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... for three leases, submit three times the fee for “Assignment and transfer of record title or operating... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false What filing fees and forms does a transfer... LEASING Transfers § 3216.14 What filing fees and forms does a transfer require? With each transfer request...

  6. 43 CFR 3216.14 - What filing fees and forms does a transfer require?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... for three leases, submit three times the fee for “Assignment and transfer of record title or operating... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false What filing fees and forms does a transfer... LEASING Transfers § 3216.14 What filing fees and forms does a transfer require? With each transfer request...

  7. 43 CFR 3602.14 - What kind of financial security does BLM require?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false What kind of financial security does BLM...? (a) For contracts of $2,000 or more, BLM will require a performance bond of an amount sufficient to... post a performance bond. (b) BLM may require a performance bond for contracts of less than $2,000. We...

  8. 43 CFR 3602.14 - What kind of financial security does BLM require?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false What kind of financial security does BLM...? (a) For contracts of $2,000 or more, BLM will require a performance bond of an amount sufficient to... post a performance bond. (b) BLM may require a performance bond for contracts of less than $2,000. We...

  9. 43 CFR 3602.14 - What kind of financial security does BLM require?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false What kind of financial security does BLM...? (a) For contracts of $2,000 or more, BLM will require a performance bond of an amount sufficient to... post a performance bond. (b) BLM may require a performance bond for contracts of less than $2,000. We...

  10. Does gingival recession require surgical treatment?

    PubMed Central

    Chan, Hsun-Liang; Chun, Yong-Hee Patricia; MacEachern, Mark

    2016-01-01

    Gingival recession represents a clinical condition in adults frequently encountered in the general dental practice. It is estimated that 23% of adults in the US have one or more tooth surfaces with ≥ 3 mm gingival recession. Clinicians often time face dilemmas of whether or not to treat such a condition surgically. Therefore, we were charged by the editorial board to answer this critical question: “Does gingival recession require surgical treatment?” An initial condensed literature search was performed using a combination of gingival recession and surgery controlled terms and keywords. An analysis of the search results highlights our limited understanding of the factors that often guide the treatment of gingival recession. Understanding the etiology, prognosis and treatment of gingival recession continues to offer many unanswered questions and challenges in the field of periodontics as we strive to provide the best care possible for our patients. PMID:26427577

  11. 7 CFR 170.9 - What type of information does the application require?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) MISCELLANEOUS MARKETING PRACTICES UNDER THE AGRICULTURAL MARKETING ACT OF 1946 USDA FARMERS MARKET § 170.9 What type of information does the application require? The application for participation in the USDA Farmers...

  12. 7 CFR 170.9 - What type of information does the application require?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) MISCELLANEOUS MARKETING PRACTICES UNDER THE AGRICULTURAL MARKETING ACT OF 1946 USDA FARMERS MARKET § 170.9 What type of information does the application require? The application for participation in the USDA Farmers...

  13. 13 CFR 124.603 - What reports regarding the continued business operations of former Participants does SBA require?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... continued business operations of former Participants does SBA require? 124.603 Section 124.603 Business... What reports regarding the continued business operations of former Participants does SBA require... continued business operations, contracts, and financial condition for a period of three years following the...

  14. Guide to good practices for operations and administration updates through required reading

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1998-12-01

    This Guide to Good Practices is written to enhance understanding of, and provide direction for, Required Reading, Chapter XIV of Department of Energy (DOE) Order 5480.19, Conduct of Operations Requirements for DOE Facilities. The practices in this guide should be considered when planning or reviewing programs for updating personnel with operations and administration information through required reading. Contractors are advised to adopt procedures that meet the intent of DOE Order 5480.19. Required Reading is an element of an effective Conduct of Operations program. The complexity and array of activities performed in DOE facilities dictate the necessity for a coordinated requiredmore » reading program to promote safe and efficient operations.« less

  15. 21 CFR 1311.50 - Requirements for recipients of digitally signed orders.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... REQUIREMENTS FOR ELECTRONIC ORDERS AND PRESCRIPTIONS Obtaining and Using Digital Certificates for Electronic... digital certificate has not expired by checking the expiration date against the date the order was signed...

  16. 25 CFR 1000.396 - Does a Tribe/Consortium have additional ongoing requirements to maintain minimum standards for...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false Does a Tribe/Consortium have additional ongoing requirements to maintain minimum standards for Tribe/Consortium management systems? 1000.396 Section 1000.396... Miscellaneous Provisions § 1000.396 Does a Tribe/Consortium have additional ongoing requirements to maintain...

  17. 45 CFR 261.16 - Does the imposition of a penalty affect an individual's work requirement?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OF HEALTH AND HUMAN SERVICES ENSURING THAT RECIPIENTS WORK What Are the Provisions Addressing Individual Responsibility? § 261.16 Does the imposition of a penalty affect an individual's work requirement... 45 Public Welfare 2 2010-10-01 2010-10-01 false Does the imposition of a penalty affect an...

  18. Exemptions form PSD Permit Requirements for Coal Conversions Resulting from DOE Prohibition Orders

    EPA Pesticide Factsheets

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  19. Building a Web-based drug ordering system for hospitals: from requirements engineering to prototyping.

    PubMed

    Hübner, U; Klein, F; Hofstetter, J; Kammeyer, G; Seete, H

    2000-01-01

    Web-based drug ordering allows a growing number of hospitals without pharmacy to communicate seamlessly with their external pharmacy. Business process analysis and object oriented modelling performed together with the users at a pilot hospital resulted in a comprehensive picture of the user and business requirements for electronic drug ordering. The user requirements were further validated with the help of a software prototype. In order to capture the needs of a large number of users CAP10, a new method making use of pre-built models, is proposed. Solutions for coping with the technical requirements (interfacing the business software at the pharmacy) and with the legal requirements (signing the orders) are presented.

  20. 21 CFR 1311.55 - Requirements for systems used to process digitally signed orders.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... identification and password combination or biometric authentication to access the private key. Activation data... source. (9) The system must archive the digitally signed orders and any other records required in part... linked records for orders signed with a CSOS digital certificate must meet the following requirements: (1...

  1. 21 CFR 1311.55 - Requirements for systems used to process digitally signed orders.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... identification and password combination or biometric authentication to access the private key. Activation data... source. (9) The system must archive the digitally signed orders and any other records required in part... linked records for orders signed with a CSOS digital certificate must meet the following requirements: (1...

  2. 21 CFR 1311.55 - Requirements for systems used to process digitally signed orders.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... identification and password combination or biometric authentication to access the private key. Activation data... source. (9) The system must archive the digitally signed orders and any other records required in part... linked records for orders signed with a CSOS digital certificate must meet the following requirements: (1...

  3. 21 CFR 1311.55 - Requirements for systems used to process digitally signed orders.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... identification and password combination or biometric authentication to access the private key. Activation data... source. (9) The system must archive the digitally signed orders and any other records required in part... linked records for orders signed with a CSOS digital certificate must meet the following requirements: (1...

  4. 10 CFR 727.5 - What acknowledgment and consent is required for access to information on DOE computers?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... information on DOE computers? 727.5 Section 727.5 Energy DEPARTMENT OF ENERGY CONSENT FOR ACCESS TO INFORMATION ON DEPARTMENT OF ENERGY COMPUTERS § 727.5 What acknowledgment and consent is required for access to information on DOE computers? An individual may not be granted access to information on a DOE...

  5. 10 CFR 727.5 - What acknowledgment and consent is required for access to information on DOE computers?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... information on DOE computers? 727.5 Section 727.5 Energy DEPARTMENT OF ENERGY CONSENT FOR ACCESS TO INFORMATION ON DEPARTMENT OF ENERGY COMPUTERS § 727.5 What acknowledgment and consent is required for access to information on DOE computers? An individual may not be granted access to information on a DOE...

  6. 10 CFR 727.5 - What acknowledgment and consent is required for access to information on DOE computers?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... information on DOE computers? 727.5 Section 727.5 Energy DEPARTMENT OF ENERGY CONSENT FOR ACCESS TO INFORMATION ON DEPARTMENT OF ENERGY COMPUTERS § 727.5 What acknowledgment and consent is required for access to information on DOE computers? An individual may not be granted access to information on a DOE...

  7. 10 CFR 727.5 - What acknowledgment and consent is required for access to information on DOE computers?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... information on DOE computers? 727.5 Section 727.5 Energy DEPARTMENT OF ENERGY CONSENT FOR ACCESS TO INFORMATION ON DEPARTMENT OF ENERGY COMPUTERS § 727.5 What acknowledgment and consent is required for access to information on DOE computers? An individual may not be granted access to information on a DOE...

  8. 10 CFR 727.5 - What acknowledgment and consent is required for access to information on DOE computers?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... information on DOE computers? 727.5 Section 727.5 Energy DEPARTMENT OF ENERGY CONSENT FOR ACCESS TO INFORMATION ON DEPARTMENT OF ENERGY COMPUTERS § 727.5 What acknowledgment and consent is required for access to information on DOE computers? An individual may not be granted access to information on a DOE...

  9. 13 CFR 109.440 - Requirements imposed under other laws and orders.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... laws and orders. 109.440 Section 109.440 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION... Requirements imposed under other laws and orders. Loans made by the ILP Intermediary under this program must comply with all applicable laws, including §§ 120.170 (Flood insurance), 120.172 (Flood-plain and...

  10. 13 CFR 109.440 - Requirements imposed under other laws and orders.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... laws and orders. 109.440 Section 109.440 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION... Requirements imposed under other laws and orders. Loans made by the ILP Intermediary under this program must comply with all applicable laws, including §§ 120.170 (Flood insurance), 120.172 (Flood-plain and...

  11. 13 CFR 109.440 - Requirements imposed under other laws and orders.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... laws and orders. 109.440 Section 109.440 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION... Requirements imposed under other laws and orders. Loans made by the ILP Intermediary under this program must comply with all applicable laws, including §§ 120.170 (Flood insurance), 120.172 (Flood-plain and...

  12. EMP Attachment 3 DOE-SC PNNL Site Dose Assessment Guidance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Snyder, Sandra F.

    2011-12-21

    This Dose Assessment Guidance (DAG) describes methods to use to determine the Maximally-Exposed Individual (MEI) location and to estimate dose impact to that individual under the U.S. Department of Energy Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Site Environmental Monitoring Plan (EMP). This guidance applies to public dose from radioactive material releases to the air from PNNL Site operations. This document is an attachment to the Pacific Northwest National Laboratory (PNNL) Environmental Monitoring Plan (EMP) and describes dose assessment guidance for radiological air emissions. The impact of radiological air emissions from the U.S. Department of Energy Office ofmore » Science (DOE-SC) PNNL Site is indicated by dose estimates to a maximally exposed member of the public, referred to as the maximally exposed individual (MEI). Reporting requirements associated with dose to members of the public from radiological air emissions are in 40 CFR Part 61.94, WAC 246-247-080, and DOE Order 458.1. The DOE Order and state standards for dose from radioactive air emissions are consistent with U.S. Environmental Protection Agency (EPA) dose standards in 40 CFR 61.92 (i.e., 10 mrem/yr to a MEI). Despite the fact that the current Contract Requirements Document (CRD) for the DOE-SC PNNL Site operations does not include the requirement to meet DOE CRD 458.1, paragraph 2.b, public dose limits, the DOE dose limits would be met when EPA limits are met.« less

  13. 13 CFR 123.11 - Does SBA require collateral for any of its disaster loans?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Does SBA require collateral for any of its disaster loans? 123.11 Section 123.11 Business Credit and Assistance SMALL BUSINESS...? Generally, SBA will not require that you pledge collateral to secure a disaster home loan or a physical...

  14. The Supreme Court Holds That Section 504 Does Not Require Affirmative Action.

    ERIC Educational Resources Information Center

    Flygare, Thomas J.

    1979-01-01

    In deciding that a person with a serious hearing handicap could be denied entry into a nursing program, the Supreme Court held that Section 504 of the Rehabilitation Act of 1973 does not require affirmative action but imposes the lesser obligation that institutions avoid discrimination against handicapped persons. (Author/IRT)

  15. TA-55 Final Safety Analysis Report Comparison Document and DOE Safety Evaluation Report Requirements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Alan Bond

    2001-04-01

    This document provides an overview of changes to the currently approved TA-55 Final Safety Analysis Report (FSAR) that are included in the upgraded FSAR. The DOE Safety Evaluation Report (SER) requirements that are incorporated into the upgraded FSAR are briefly discussed to provide the starting point in the FSAR with respect to the SER requirements.

  16. 14 CFR 13.20 - Orders of compliance, cease and desist orders, orders of denial, and other orders.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Orders of compliance, cease and desist orders, orders of denial, and other orders. 13.20 Section 13.20 Aeronautics and Space FEDERAL AVIATION... 1982 as amended by the Airport and Airway Safety and Capacity Expansion Act of 1987. This section does...

  17. 14 CFR 13.20 - Orders of compliance, cease and desist orders, orders of denial, and other orders.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Orders of compliance, cease and desist orders, orders of denial, and other orders. 13.20 Section 13.20 Aeronautics and Space FEDERAL AVIATION... 1982 as amended by the Airport and Airway Safety and Capacity Expansion Act of 1987. This section does...

  18. 30 CFR 250.195 - What notification does MMS require on the production status of wells?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the well in a production status. You must confirm oral notification by telefax or e-mail within those... production status of wells? 250.195 Section 250.195 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT... Information and Reporting Requirements § 250.195 What notification does MMS require on the production status...

  19. 41 CFR 102-192.95 - Why does GSA require annual mail management reports?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... under the Federal Records Act, especially with regards to sharing best practices, training, standards... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Why does GSA require annual mail management reports? 102-192.95 Section 102-192.95 Public Contracts and Property Management...

  20. 41 CFR 102-192.95 - Why does GSA require annual mail management reports?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... under the Federal Records Act, especially with regards to sharing best practices, training, standards... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Why does GSA require annual mail management reports? 102-192.95 Section 102-192.95 Public Contracts and Property Management...

  1. 41 CFR 102-192.95 - Why does GSA require annual mail management reports?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... under the Federal Records Act, especially with regards to sharing best practices, training, standards... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Why does GSA require annual mail management reports? 102-192.95 Section 102-192.95 Public Contracts and Property Management...

  2. 41 CFR 102-192.95 - Why does GSA require annual mail management reports?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... under the Federal Records Act, especially with regards to sharing best practices, training, standards... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Why does GSA require annual mail management reports? 102-192.95 Section 102-192.95 Public Contracts and Property Management...

  3. 41 CFR 102-192.95 - Why does GSA require annual mail management reports?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... under the Federal Records Act, especially with regards to sharing best practices, training, standards... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Why does GSA require annual mail management reports? 102-192.95 Section 102-192.95 Public Contracts and Property Management...

  4. Combining states without scale hierarchies with ordered parton showers

    DOE PAGES

    Fischer, Nadine; Prestel, Stefan

    2017-09-12

    Here, we present a parameter-free scheme to combine fixed-order multi-jet results with parton-shower evolution. The scheme produces jet cross sections with leading-order accuracy in the complete phase space of multiple emissions, resumming large logarithms when appropriate, while not arbitrarily enforcing ordering on momentum configurations beyond the reach of the parton-shower evolution equation. This then requires the development of a matrix-element correction scheme for complex phase-spaces including ordering conditions as well as a systematic scale-setting procedure for unordered phase-space points. Our algorithm does not require a merging-scale parameter. We implement the new method in the Vincia framework and compare to LHCmore » data.« less

  5. 25 CFR 12.36 - Does other law enforcement training count?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Does other law enforcement training count? 12.36 Section 12.36 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER INDIAN COUNTRY LAW ENFORCEMENT Qualifications and Training Requirements § 12.36 Does other law enforcement training count? All requests for evaluation of equivalent...

  6. Accuracy-preserving source term quadrature for third-order edge-based discretization

    NASA Astrophysics Data System (ADS)

    Nishikawa, Hiroaki; Liu, Yi

    2017-09-01

    In this paper, we derive a family of source term quadrature formulas for preserving third-order accuracy of the node-centered edge-based discretization for conservation laws with source terms on arbitrary simplex grids. A three-parameter family of source term quadrature formulas is derived, and as a subset, a one-parameter family of economical formulas is identified that does not require second derivatives of the source term. Among the economical formulas, a unique formula is then derived that does not require gradients of the source term at neighbor nodes, thus leading to a significantly smaller discretization stencil for source terms. All the formulas derived in this paper do not require a boundary closure, and therefore can be directly applied at boundary nodes. Numerical results are presented to demonstrate third-order accuracy at interior and boundary nodes for one-dimensional grids and linear triangular/tetrahedral grids over straight and curved geometries.

  7. 25 CFR 20.201 - How does the Bureau designate a service area and what information is required?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false How does the Bureau designate a service area and what information is required? 20.201 Section 20.201 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Welfare Reform § 20.201 How does the...

  8. 25 CFR 20.201 - How does the Bureau designate a service area and what information is required?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false How does the Bureau designate a service area and what information is required? 20.201 Section 20.201 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Welfare Reform § 20.201 How does the...

  9. 25 CFR 20.201 - How does the Bureau designate a service area and what information is required?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true How does the Bureau designate a service area and what information is required? 20.201 Section 20.201 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Welfare Reform § 20.201 How does the...

  10. 25 CFR 20.201 - How does the Bureau designate a service area and what information is required?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false How does the Bureau designate a service area and what information is required? 20.201 Section 20.201 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Welfare Reform § 20.201 How does the...

  11. 25 CFR 20.201 - How does the Bureau designate a service area and what information is required?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How does the Bureau designate a service area and what information is required? 20.201 Section 20.201 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Welfare Reform § 20.201 How does the...

  12. Ezetimibe-sensitive cholesterol uptake by NPC1L1 protein does not require endocytosis

    PubMed Central

    Johnson, Tory A.; Pfeffer, Suzanne R.

    2016-01-01

    Human NPC1L1 protein mediates cholesterol absorption in the intestine and liver and is the target of the drug ezetimibe, which is used to treat hypercholesterolemia. Previous studies concluded that NPC1L1-GFP protein trafficking is regulated by cholesterol binding and that ezetimibe blocks NPC1L1-GFP function by inhibiting its endocytosis. We used cell surface biotinylation to monitor NPC1L1-GFP endocytosis and show that ezetimibe does not alter the rate of NPC1L1-GFP endocytosis in cultured rat hepatocytes grown under normal growth conditions. As expected, NPC1L1-GFP endocytosis depends in part on C-terminal, cytoplasmically oriented sequences, but endocytosis does not require cholesterol binding to NPC1L1’s N-terminal domain. In addition, two small- molecule inhibitors of general (and NPC1L1-GFP) endocytosis failed to inhibit the ezetimibe-sensitive uptake of [3H]cholesterol from taurocholate micelles. These experiments demonstrate that cholesterol uptake by NPC1L1 does not require endocytosis; moreover, ezetimibe interferes with NPC1L1’s cholesterol adsorption activity without blocking NPC1L1 internalization in RH7777 cells. PMID:27075173

  13. 18 CFR 35.19a - Refund requirements under suspension orders.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Refund requirements under suspension orders. 35.19a Section 35.19a Conservation of Power and Water Resources FEDERAL ENERGY... October 10, 1974, and September 30, 1979; and (iii)(A) At an average prime rate for each calendar quarter...

  14. 18 CFR 35.19a - Refund requirements under suspension orders.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Refund requirements under suspension orders. 35.19a Section 35.19a Conservation of Power and Water Resources FEDERAL ENERGY... October 10, 1974, and September 30, 1979; and (iii)(A) At an average prime rate for each calendar quarter...

  15. 18 CFR 35.19a - Refund requirements under suspension orders.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Refund requirements under suspension orders. 35.19a Section 35.19a Conservation of Power and Water Resources FEDERAL ENERGY... October 10, 1974, and September 30, 1979; and (iii)(A) At an average prime rate for each calendar quarter...

  16. 18 CFR 35.19a - Refund requirements under suspension orders.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Refund requirements under suspension orders. 35.19a Section 35.19a Conservation of Power and Water Resources FEDERAL ENERGY... October 10, 1974, and September 30, 1979; and (iii)(A) At an average prime rate for each calendar quarter...

  17. Sixth- and eighth-order Hermite integrator for N-body simulations

    NASA Astrophysics Data System (ADS)

    Nitadori, Keigo; Makino, Junichiro

    2008-10-01

    We present sixth- and eighth-order Hermite integrators for astrophysical N-body simulations, which use the derivatives of accelerations up to second-order ( snap) and third-order ( crackle). These schemes do not require previous values for the corrector, and require only one previous value to construct the predictor. Thus, they are fairly easy to implement. The additional cost of the calculation of the higher-order derivatives is not very high. Even for the eighth-order scheme, the number of floating-point operations for force calculation is only about two times larger than that for traditional fourth-order Hermite scheme. The sixth-order scheme is better than the traditional fourth-order scheme for most cases. When the required accuracy is very high, the eighth-order one is the best. These high-order schemes have several practical advantages. For example, they allow a larger number of particles to be integrated in parallel than the fourth-order scheme does, resulting in higher execution efficiency in both general-purpose parallel computers and GRAPE systems.

  18. EVALUATING THE IMPORTANCE OF FACTORS IN ANY GIVEN ORDER OF FACTORING.

    PubMed

    Humphreys, L G; Tucker, L R; Dachler, P

    1970-04-01

    A methodology has been described and illustrated for obtaining an evaluation of the importance of the factors in a particular order of factoring that does not require faotoring beyond that order. For example, one can estimate the intercorrelations of the original measures with the perturbations of the first-order factor held constant or, the reverse, estimate the contribution to the intercorrelations of the originral measures from the first-order factors alone. Similar operations are possible at higher orders.

  19. 34 CFR 403.184 - How does a State request a waiver of the maintenance of effort requirement?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... APPLIED TECHNOLOGY EDUCATION PROGRAM What Financial Conditions Must Be Met by a State? § 403.184 How does... 34 Education 3 2010-07-01 2010-07-01 false How does a State request a waiver of the maintenance of effort requirement? 403.184 Section 403.184 Education Regulations of the Offices of the Department of...

  20. 34 CFR 403.184 - How does a State request a waiver of the maintenance of effort requirement?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... APPLIED TECHNOLOGY EDUCATION PROGRAM What Financial Conditions Must Be Met by a State? § 403.184 How does... 34 Education 3 2013-07-01 2013-07-01 false How does a State request a waiver of the maintenance of effort requirement? 403.184 Section 403.184 Education Regulations of the Offices of the Department of...

  1. 34 CFR 403.184 - How does a State request a waiver of the maintenance of effort requirement?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... APPLIED TECHNOLOGY EDUCATION PROGRAM What Financial Conditions Must Be Met by a State? § 403.184 How does... 34 Education 3 2014-07-01 2014-07-01 false How does a State request a waiver of the maintenance of effort requirement? 403.184 Section 403.184 Education Regulations of the Offices of the Department of...

  2. 34 CFR 403.184 - How does a State request a waiver of the maintenance of effort requirement?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... APPLIED TECHNOLOGY EDUCATION PROGRAM What Financial Conditions Must Be Met by a State? § 403.184 How does... 34 Education 3 2012-07-01 2012-07-01 false How does a State request a waiver of the maintenance of effort requirement? 403.184 Section 403.184 Education Regulations of the Offices of the Department of...

  3. 34 CFR 403.184 - How does a State request a waiver of the maintenance of effort requirement?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... APPLIED TECHNOLOGY EDUCATION PROGRAM What Financial Conditions Must Be Met by a State? § 403.184 How does... 34 Education 3 2011-07-01 2011-07-01 false How does a State request a waiver of the maintenance of effort requirement? 403.184 Section 403.184 Education Regulations of the Offices of the Department of...

  4. Aerobic kinetoplastid flagellate Phytomonas does not require heme for viability

    PubMed Central

    Kořený, Luděk; Sobotka, Roman; Kovářová, Julie; Gnipová, Anna; Flegontov, Pavel; Horváth, Anton; Oborník, Miroslav; Ayala, Francisco J.; Lukeš, Julius

    2012-01-01

    Heme is an iron-coordinated porphyrin that is universally essential as a protein cofactor for fundamental cellular processes, such as electron transport in the respiratory chain, oxidative stress response, or redox reactions in various metabolic pathways. Parasitic kinetoplastid flagellates represent a rare example of organisms that depend on oxidative metabolism but are heme auxotrophs. Here, we show that heme is fully dispensable for the survival of Phytomonas serpens, a plant parasite. Seeking to understand the metabolism of this heme-free eukaryote, we searched for heme-containing proteins in its de novo sequenced genome and examined several cellular processes for which heme has so far been considered indispensable. We found that P. serpens lacks most of the known hemoproteins and does not require heme for electron transport in the respiratory chain, protection against oxidative stress, or desaturation of fatty acids. Although heme is still required for the synthesis of ergosterol, its precursor, lanosterol, is instead incorporated into the membranes of P. serpens grown in the absence of heme. In conclusion, P. serpens is a flagellate with unique metabolic adaptations that allow it to bypass all requirements for heme. PMID:22355128

  5. Aerobic kinetoplastid flagellate Phytomonas does not require heme for viability.

    PubMed

    Kořený, Luděk; Sobotka, Roman; Kovářová, Julie; Gnipová, Anna; Flegontov, Pavel; Horváth, Anton; Oborník, Miroslav; Ayala, Francisco J; Lukeš, Julius

    2012-03-06

    Heme is an iron-coordinated porphyrin that is universally essential as a protein cofactor for fundamental cellular processes, such as electron transport in the respiratory chain, oxidative stress response, or redox reactions in various metabolic pathways. Parasitic kinetoplastid flagellates represent a rare example of organisms that depend on oxidative metabolism but are heme auxotrophs. Here, we show that heme is fully dispensable for the survival of Phytomonas serpens, a plant parasite. Seeking to understand the metabolism of this heme-free eukaryote, we searched for heme-containing proteins in its de novo sequenced genome and examined several cellular processes for which heme has so far been considered indispensable. We found that P. serpens lacks most of the known hemoproteins and does not require heme for electron transport in the respiratory chain, protection against oxidative stress, or desaturation of fatty acids. Although heme is still required for the synthesis of ergosterol, its precursor, lanosterol, is instead incorporated into the membranes of P. serpens grown in the absence of heme. In conclusion, P. serpens is a flagellate with unique metabolic adaptations that allow it to bypass all requirements for heme.

  6. 31 CFR 363.28 - Does Public Debt reserve the right to require that any TreasuryDirect ® transaction be conducted...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Does Public Debt reserve the right to... Provisions Governing Securities Held in TreasuryDirect § 363.28 Does Public Debt reserve the right to require that any TreasuryDirect ® transaction be conducted in paper form? We reserve the right to require any...

  7. 13 CFR 123.513 - Does SBA require collateral on its Military Reservist EIDL?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., or both. SBA will not decline a loan if you do not have a particular amount of collateral so long as SBA is reasonably sure that you can repay the loan. If you refuse to pledge the available collateral... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Does SBA require collateral on its...

  8. 10 CFR 712.11 - General requirements for HRP certification.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false General requirements for HRP certification. 712.11 Section 712.11 Energy DEPARTMENT OF ENERGY HUMAN RELIABILITY PROGRAM Establishment of and Procedures for the... provisions of 10 CFR part 707 for DOE contractors, and DOE Order 3792.3, “Drug-Free Federal Workplace Testing...

  9. Department of Energy Order 440.2: Aviation

    DOT National Transportation Integrated Search

    1995-10-26

    Archival copy of Department of Energy (DOE) Order 440.2 regulating aviation safety of : aircraft used by DOE. Superseded by DOE O 440.2A dated March 8, 2002. For latest : listing of DOE directives and orders, users should consult DOE Directives, Regu...

  10. 24 CFR 1000.242 - When does the requirement for exemption from taxation apply to affordable housing activities?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... exemption from taxation apply to affordable housing activities? 1000.242 Section 1000.242 Housing and Urban... ACTIVITIES Indian Housing Plan (IHP) § 1000.242 When does the requirement for exemption from taxation apply to affordable housing activities? The requirement for exemption from taxation applies only to rental...

  11. 24 CFR 1000.242 - When does the requirement for exemption from taxation apply to affordable housing activities?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... exemption from taxation apply to affordable housing activities? 1000.242 Section 1000.242 Housing and Urban... ACTIVITIES Indian Housing Plan (IHP) § 1000.242 When does the requirement for exemption from taxation apply to affordable housing activities? The requirement for exemption from taxation applies only to rental...

  12. Root growth regulation and gravitropism in maize roots does not require the epidermis

    NASA Technical Reports Server (NTRS)

    Bjorkman, T.; Cleland, R. E.

    1991-01-01

    We have earlier published observations showing that endogenous alterations in growth rate during gravitropism in maize roots (Zea mays L.) are unaffected by the orientation of cuts which remove epidermal and cortical tissue in the growing zone (Bjorkman and Cleland, 1988, Planta 176, 513-518). We concluded that the epidermis and cortex are not essential for transporting a growth-regulating signal in gravitropism or straight growth, nor for regulating the rate of tissue expansion. This conclusion has been challenged by Yang et al. (1990, Planta 180, 530-536), who contend that a shallow girdle around the entire perimeter of the root blocks gravitropic curvature and that this inhibition is the result of a requirement for epidermal cells to transport the growth-regulating signal. In this paper we demonstrate that the entire epidermis can be removed without blocking gravitropic curvature and show that the position of narrow girdles does not affect the location of curvature. We therefore conclude that the epidermis is not required for transport of a growth-regulating substance from the root cap to the growing zone, nor does it regulate the growth rate of the elongating zone of roots.

  13. 43 CFR 404.60 - Does this rule contain an information collection that requires approval by the Office of...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Does this rule contain an information collection that requires approval by the Office of Management and Budget (OMB)? 404.60 Section 404.60 Public... RECLAMATION RURAL WATER SUPPLY PROGRAM Miscellaneous § 404.60 Does this rule contain an information collection...

  14. 40 CFR 60.1575 - How does the model rule relate to the required elements of my State plan?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false How does the model rule relate to the... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES... Before August 30, 1999 Use of Model Rule § 60.1575 How does the model rule relate to the required...

  15. 43 CFR 404.60 - Does this rule contain an information collection that requires approval by the Office of...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true Does this rule contain an information collection that requires approval by the Office of Management and Budget (OMB)? 404.60 Section 404.60 Public... RECLAMATION RURAL WATER SUPPLY PROGRAM Miscellaneous § 404.60 Does this rule contain an information collection...

  16. 43 CFR 404.60 - Does this rule contain an information collection that requires approval by the Office of...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false Does this rule contain an information collection that requires approval by the Office of Management and Budget (OMB)? 404.60 Section 404.60 Public... RECLAMATION RURAL WATER SUPPLY PROGRAM Miscellaneous § 404.60 Does this rule contain an information collection...

  17. 43 CFR 404.60 - Does this rule contain an information collection that requires approval by the Office of...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false Does this rule contain an information collection that requires approval by the Office of Management and Budget (OMB)? 404.60 Section 404.60 Public... RECLAMATION RURAL WATER SUPPLY PROGRAM Miscellaneous § 404.60 Does this rule contain an information collection...

  18. 43 CFR 404.60 - Does this rule contain an information collection that requires approval by the Office of...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Does this rule contain an information collection that requires approval by the Office of Management and Budget (OMB)? 404.60 Section 404.60 Public... RECLAMATION RURAL WATER SUPPLY PROGRAM Miscellaneous § 404.60 Does this rule contain an information collection...

  19. 40 CFR 60.2565 - How does the model rule relate to the required elements of my State plan?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 7 2012-07-01 2012-07-01 false How does the model rule relate to the... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES... of Model Rule § 60.2565 How does the model rule relate to the required elements of my State plan? Use...

  20. 40 CFR 60.2565 - How does the model rule relate to the required elements of my State plan?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 7 2013-07-01 2013-07-01 false How does the model rule relate to the... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES... of Model Rule § 60.2565 How does the model rule relate to the required elements of my State plan? Use...

  1. 40 CFR 60.2565 - How does the model rule relate to the required elements of my State plan?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 7 2014-07-01 2014-07-01 false How does the model rule relate to the... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES... of Model Rule § 60.2565 How does the model rule relate to the required elements of my State plan? Use...

  2. Does massive intraabdominal free gas require surgical intervention?

    PubMed

    Furihata, Tadashi; Furihata, Makoto; Ishikawa, Kunibumi; Kosaka, Masato; Satoh, Naoki; Kubota, Keiichi

    2016-08-28

    We describe a rare case of an 81-year-old man who presented with severe epigastralgia. A chest radiograph showed massive free gas bilaterally in the diaphragmatic spaces. Computed tomography (CT) scan also showed massive free gas in the peritoneal cavity with portal venous gas. We used a wait-and-see approach and carefully considered surgery again when the time was appropriate. The patient received conservative therapy with fasting, an intravenous infusion of antibiotics, and nasogastric intubation. The patient soon recovered and was able to start eating meals 4 d after treatment; thus, surgical intervention was avoided. Thereafter, colonoscopy examination showed pneumatosis cystoides intestinalis in the ascending colon. On retrospective review, CT scan demonstrated sporadic air-filled cysts in the ascending colon. The present case taught us a lesson: the presence of massive intraabdominal free gas with portal venous gas does not necessarily require surgical intervention. Pneumatosis cystoides intestinalis should be considered as a potential causative factor of free gas with portal venous gas when making the differential diagnosis.

  3. 25 CFR 39.219 - What happens if a residential program does not maintain residency levels required by this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What happens if a residential program does not maintain residency levels required by this subpart? 39.219 Section 39.219 Indians BUREAU OF INDIAN AFFAIRS..., Student Counts, and Verifications Residential Programs § 39.219 What happens if a residential program does...

  4. What does education have to do with the New International Economic Order

    NASA Astrophysics Data System (ADS)

    Emmerij, Louis

    1982-12-01

    Greater equality in the distribution of incomes, both nationally and internationally, and more intervention to achieve this, both by national governments and international agencies, are identified as the key ideas in the proposed NIEO. Both ideas have provoked a reaction of new conservatism, aided by the current international recession. At least in part, the power of this reaction is the result of a failure in the educational professions and institutions to respond to the requirements of an NIEO in both domestic and global terms. Although the independent effects of education on social change and income distribution have indeed been over-estimated, it remains true, nevertheless, that education does have social and economic effects. Within states, education might be reorganized so as to dissolve the current dichotomy between a `learning' childhood/adolescence and a `non-learning' adulthood. Rather, learning geared to economic activity, change and restructuring might assist both developing and industrialized states to increase incomes and adjust to the requirements of the NIEO. On the international plane, the growth of development studies and of institutions concerned with the domestic effects of international relations and commerce should facilitate a more informed understanding of the balance between self-reliance and interdependence.

  5. 20 CFR 411.410 - Does each referral from an EN to a State VR agency require its own agreement?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Does each referral from an EN to a State VR agency require its own agreement? 411.410 Section 411.410 Employees' Benefits SOCIAL SECURITY...' Participation Agreements Between Employment Networks and State Vr Agencies § 411.410 Does each referral from an...

  6. 20 CFR 411.410 - Does each referral from an EN to a State VR agency require its own agreement?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Does each referral from an EN to a State VR agency require its own agreement? 411.410 Section 411.410 Employees' Benefits SOCIAL SECURITY...' Participation Agreements Between Employment Networks and State Vr Agencies § 411.410 Does each referral from an...

  7. 20 CFR 411.410 - Does each referral from an EN to a State VR agency require its own agreement?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Does each referral from an EN to a State VR agency require its own agreement? 411.410 Section 411.410 Employees' Benefits SOCIAL SECURITY...' Participation Agreements Between Employment Networks and State Vr Agencies § 411.410 Does each referral from an...

  8. Ezetimibe-sensitive cholesterol uptake by NPC1L1 protein does not require endocytosis.

    PubMed

    Johnson, Tory A; Pfeffer, Suzanne R

    2016-06-01

    Human NPC1L1 protein mediates cholesterol absorption in the intestine and liver and is the target of the drug ezetimibe, which is used to treat hypercholesterolemia. Previous studies concluded that NPC1L1-GFP protein trafficking is regulated by cholesterol binding and that ezetimibe blocks NPC1L1-GFP function by inhibiting its endocytosis. We used cell surface biotinylation to monitor NPC1L1-GFP endocytosis and show that ezetimibe does not alter the rate of NPC1L1-GFP endocytosis in cultured rat hepatocytes grown under normal growth conditions. As expected, NPC1L1-GFP endocytosis depends in part on C-terminal, cytoplasmically oriented sequences, but endocytosis does not require cholesterol binding to NPC1L1's N-terminal domain. In addition, two small- molecule inhibitors of general (and NPC1L1-GFP) endocytosis failed to inhibit the ezetimibe-sensitive uptake of [(3)H]cholesterol from taurocholate micelles. These experiments demonstrate that cholesterol uptake by NPC1L1 does not require endocytosis; moreover, ezetimibe interferes with NPC1L1's cholesterol adsorption activity without blocking NPC1L1 internalization in RH7777 cells. © 2016 Johnson and Pfeffer. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  9. 45 CFR 286.230 - What if a Tribe does not have reasonable cause for failing to meet a requirement?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... failing to meet a requirement? 286.230 Section 286.230 Public Welfare Regulations Relating to Public... a Tribe does not have reasonable cause for failing to meet a requirement? (a) To avoid the... not claim reasonable cause for failing to meet a requirement; or (2) If we found that a Tribe did not...

  10. 45 CFR 286.230 - What if a Tribe does not have reasonable cause for failing to meet a requirement?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... failing to meet a requirement? 286.230 Section 286.230 Public Welfare Regulations Relating to Public... a Tribe does not have reasonable cause for failing to meet a requirement? (a) To avoid the... not claim reasonable cause for failing to meet a requirement; or (2) If we found that a Tribe did not...

  11. Guide to good practices for operations and administration updates through required reading

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1992-12-01

    The purpose of this Guide to Good Practices is to provide Department of Energy (DOE) contractors with information that can be used to validate and/or modify existing programs relative to Conduct of Operations. This Guide to Good Practices is part of a series of guides designed to enhance the guidelines set forth in DOE Order 5480. 19, Conduct of Operations Requirements for DOE Facilities.'' (JDB)

  12. Guide to good practices for operations and administration updates through required reading

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1992-12-01

    The purpose of this Guide to Good Practices is to provide Department of Energy (DOE) contractors with information that can be used to validate and/or modify existing programs relative to Conduct of Operations. This Guide to Good Practices is part of a series of guides designed to enhance the guidelines set forth in DOE Order 5480. 19, ``Conduct of Operations Requirements for DOE Facilities.`` (JDB)

  13. 20 CFR 411.410 - Does each referral from an EN to a State VR agency require its own agreement?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Does each referral from an EN to a State VR...' Participation Agreements Between Employment Networks and State Vr Agencies § 411.410 Does each referral from an EN to a State VR agency require its own agreement? No. The agreements between ENs and State VR...

  14. 20 CFR 411.410 - Does each referral from an EN to a State VR agency require its own agreement?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Does each referral from an EN to a State VR...' Participation Agreements Between Employment Networks and State Vr Agencies § 411.410 Does each referral from an EN to a State VR agency require its own agreement? No. The agreements between ENs and State VR...

  15. 43 CFR 428.7 - What happens if a farm operator does not submit required forms.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false What happens if a farm operator does not... BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR INFORMATION REQUIREMENTS FOR CERTAIN FARM OPERATIONS IN EXCESS OF 960 ACRES AND THE ELIGIBILITY OF CERTAIN FORMERLY EXCESS LAND § 428.7 What happens if a farm...

  16. 43 CFR 428.7 - What happens if a farm operator does not submit required forms.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false What happens if a farm operator does not... BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR INFORMATION REQUIREMENTS FOR CERTAIN FARM OPERATIONS IN EXCESS OF 960 ACRES AND THE ELIGIBILITY OF CERTAIN FORMERLY EXCESS LAND § 428.7 What happens if a farm...

  17. 30 CFR 250.177 - What additional requirements may the Regional Supervisor order for a suspension?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What additional requirements may the Regional... Suspensions § 250.177 What additional requirements may the Regional Supervisor order for a suspension? If MMS grants or directs a suspension under paragraph § 250.172(b), the Regional Supervisor may require you to...

  18. 2 CFR 902.500 - Who in the DOE determines that a recipient other than an individual violated the requirements of...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Who in the DOE determines that a recipient other than an individual violated the requirements of this part? 902.500 Section 902.500 Grants and... authorized to make the determinations under 2 CFR 182.500 for DOE, including NNSA. ...

  19. 31 CFR 30.7 - Q-7: How does a TARP recipient comply with the certification and disclosure requirements under...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false Q-7: How does a TARP recipient comply with the certification and disclosure requirements under § 30.4 (Q-4) of this part? 30.7 Section 30.7... CORPORATE GOVERNANCE § 30.7 Q-7: How does a TARP recipient comply with the certification and disclosure...

  20. 31 CFR 30.7 - Q-7: How does a TARP recipient comply with the certification and disclosure requirements under...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false Q-7: How does a TARP recipient comply with the certification and disclosure requirements under § 30.4 (Q-4) of this part? 30.7 Section 30.7... CORPORATE GOVERNANCE § 30.7 Q-7: How does a TARP recipient comply with the certification and disclosure...

  1. 31 CFR 30.7 - Q-7: How does a TARP recipient comply with the certification and disclosure requirements under...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false Q-7: How does a TARP recipient comply with the certification and disclosure requirements under § 30.4 (Q-4) of this part? 30.7 Section 30.7... CORPORATE GOVERNANCE § 30.7 Q-7: How does a TARP recipient comply with the certification and disclosure...

  2. DOE-OES-EML quality assurance program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sanderson, C.G.

    1980-01-01

    Contractor laboratories handling radioactive materials for the US Department of Energy (DOE) are required to monitor the environmental exposure and publish annual reports for the Division of Operational and Environmental Safety (OES). In order to determine the validity of the data contained in these reports the Environmental Measurements Laboratory (EML) was requested to develop, coordinate, and conduct an Environmental Quality Assurance Program (QAP). There are four major phases to the DOE-OES-EML Quality Assurance Program: sample collection and preparation, sample analyses at EML, quarterly sample distribution, and reporting the data returned by the participants. The various phases of the QAP andmore » the data reported during the first year of the program are discussed.« less

  3. Environmental Requirements Management

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cusack, Laura J.; Bramson, Jeffrey E.; Archuleta, Jose A.

    2015-01-08

    CH2M HILL Plateau Remediation Company (CH2M HILL) is the U.S. Department of Energy (DOE) prime contractor responsible for the environmental cleanup of the Hanford Site Central Plateau. As part of this responsibility, the CH2M HILL is faced with the task of complying with thousands of environmental requirements which originate from over 200 federal, state, and local laws and regulations, DOE Orders, waste management and effluent discharge permits, Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) response and Resource Conservation and Recovery Act (RCRA) corrective action documents, and official regulatory agency correspondence. The challenge is to manage this vast number ofmore » requirements to ensure they are appropriately and effectively integrated into CH2M HILL operations. Ensuring compliance with a large number of environmental requirements relies on an organization’s ability to identify, evaluate, communicate, and verify those requirements. To ensure that compliance is maintained, all changes need to be tracked. The CH2M HILL identified that the existing system used to manage environmental requirements was difficult to maintain and that improvements should be made to increase functionality. CH2M HILL established an environmental requirements management procedure and tools to assure that all environmental requirements are effectively and efficiently managed. Having a complete and accurate set of environmental requirements applicable to CH2M HILL operations will promote a more efficient approach to: • Communicating requirements • Planning work • Maintaining work controls • Maintaining compliance« less

  4. 20 CFR 411.375 - Does a State VR agency continue to provide services under the requirements of the State plan...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Does a State VR agency continue to provide... Rehabilitation Agencies' Participation Participation in the Ticket to Work Program § 411.375 Does a State VR.... The State VR agency must continue to provide services under the requirements of the State plan...

  5. 20 CFR 411.375 - Does a State VR agency continue to provide services under the requirements of the State plan...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Does a State VR agency continue to provide... Rehabilitation Agencies' Participation Participation in the Ticket to Work Program § 411.375 Does a State VR.... The State VR agency must continue to provide services under the requirements of the State plan...

  6. 42 CFR 136.404 - What does the Indian Child Protection and Family Violence Prevention Act require of the IHS and...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false What does the Indian Child Protection and Family Violence Prevention Act require of the IHS and Indian Tribes or Tribal organizations receiving funds under... Protection and Family Violence Prevention § 136.404 What does the Indian Child Protection and Family Violence...

  7. 20 CFR 411.375 - Does a State VR agency continue to provide services under the requirements of the State plan...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Does a State VR agency continue to provide... Rehabilitation Agencies' Participation Participation in the Ticket to Work Program § 411.375 Does a State VR.... The State VR agency must continue to provide services under the requirements of the State plan...

  8. 20 CFR 411.375 - Does a State VR agency continue to provide services under the requirements of the State plan...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Does a State VR agency continue to provide... Rehabilitation Agencies' Participation Participation in the Ticket to Work Program § 411.375 Does a State VR.... The State VR agency must continue to provide services under the requirements of the State plan...

  9. 20 CFR 411.375 - Does a State VR agency continue to provide services under the requirements of the State plan...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Does a State VR agency continue to provide... Rehabilitation Agencies' Participation Participation in the Ticket to Work Program § 411.375 Does a State VR.... The State VR agency must continue to provide services under the requirements of the State plan...

  10. 20 CFR 652.207 - How does a State meet the requirement for universal access to services provided under the Act?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false How does a State meet the requirement for universal access to services provided under the Act? 652.207 Section 652.207 Employees' Benefits EMPLOYMENT... exercising this discretion, a State must meet the Act's requirements. (b) These requirements are: (1) Labor...

  11. Does this adult patient with suspected bacteremia require blood cultures?

    PubMed

    Coburn, Bryan; Morris, Andrew M; Tomlinson, George; Detsky, Allan S

    2012-08-01

    Clinicians order blood cultures liberally among patients in whom bacteremia is suspected, though a small proportion of blood cultures yield true-positive results. Ordering blood cultures inappropriately may be both wasteful and harmful. To review the accuracy of easily obtained clinical and laboratory findings to inform the decision to obtain blood cultures in suspected bacteremia. A MEDLINE and EMBASE search (inception to April 2012) yielded 35 studies that met inclusion criteria for evaluating the accuracy of clinical variables for bacteremia in adult immunocompetent patients, representing 4566 bacteremia and 25,946 negative blood culture episodes. Data were extracted to determine the prevalence and likelihood ratios (LRs) of findings for bacteremia. The pretest probability of bacteremia varies depending on the clinical context, from low (eg, cellulitis: 2%) to high (eg, septic shock: 69%). Elevated temperatures alone do not accurately predict bacteremia (for ≥38°C [>100.3°F], LR, 1.9 [95% CI, 1.4-2.4]; for ≥38.5°C [>101.2°F], LR, 1.4 [95% CI, 1.1-2.0]), nor does isolated leukocytosis (LR, <1.7). The severity of chills graded on an ordinal scale (shaking chills, LR, 4.7; 95% CI, 3.0-7.2) may be more useful. Both the systemic inflammatory response syndrome (SIRS) and a multivariable decision rule with major and minor criteria are sensitive (but not specific) predictors of bacteremia (SIRS, negative LR, 0.09 [95% CI, 0.03-0.26]; decision rule, negative LR, 0.08 [95% CI, 0.04-0.17]). Blood cultures should not be ordered for adult patients with isolated fever or leukocytosis without considering the pretest probability. SIRS and the decision rule may be helpful in identifying patients who do not need blood cultures. These conclusions do not apply to immunocompromised patients or when endocarditis is suspected.

  12. Role Sequencing: Does Order Matter for Mental Health?

    ERIC Educational Resources Information Center

    Jackson, Pamela Braboy

    2004-01-01

    Role sequencing refers to the ordering of social roles. According to the normative order hypothesis, adults who follow a certain sequencing of their social roles will be better adjusted than their peers who follow other life course patterns. The normative order is defined as first entering the paid labor force, getting married, and later having…

  13. 2 CFR 902.505 - Who in the DOE determines that a recipient who is an individual violated the requirements of this...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Who in the DOE determines that a recipient who is an individual violated the requirements of this part? 902.505 Section 902.505 Grants and... make the determinations under 2 CFR 182.500 for DOE, including NNSA. ...

  14. 13 CFR 124.601 - What reports does SBA require concerning parties who assist Participants in obtaining federal...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What reports does SBA require concerning parties who assist Participants in obtaining federal contracts? 124.601 Section 124.601 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION 8(a) BUSINESS DEVELOPMENT/SMALL DISADVANTAGED...

  15. Reduced-order modeling for hyperthermia: an extended balanced-realization-based approach.

    PubMed

    Mattingly, M; Bailey, E A; Dutton, A W; Roemer, R B; Devasia, S

    1998-09-01

    Accurate thermal models are needed in hyperthermia cancer treatments for such tasks as actuator and sensor placement design, parameter estimation, and feedback temperature control. The complexity of the human body produces full-order models which are too large for effective execution of these tasks, making use of reduced-order models necessary. However, standard balanced-realization (SBR)-based model reduction techniques require a priori knowledge of the particular placement of actuators and sensors for model reduction. Since placement design is intractable (computationally) on the full-order models, SBR techniques must use ad hoc placements. To alleviate this problem, an extended balanced-realization (EBR)-based model-order reduction approach is presented. The new technique allows model order reduction to be performed over all possible placement designs and does not require ad hoc placement designs. It is shown that models obtained using the EBR method are more robust to intratreatment changes in the placement of the applied power field than those models obtained using the SBR method.

  16. 25 CFR 224.41 - When does the Secretary require agreement of more than one tribe to approve a TERA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT General Provisions § 224.41 When does the Secretary require agreement of...

  17. 49 CFR 40.208 - What problem requires corrective action but does not result in the cancellation of a test?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false What problem requires corrective action but does not result in the cancellation of a test? 40.208 Section 40.208 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Problems in Drug Tests § 40.208 What problem requires...

  18. High-level waste storage tank farms/242-A evaporator standards/requirements identification document (S/RID), Vol. 7

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1994-04-01

    This Requirements Identification Document (RID) describes an Occupational Health and Safety Program as defined through the Relevant DOE Orders, regulations, industry codes/standards, industry guidance documents and, as appropriate, good industry practice. The definition of an Occupational Health and Safety Program as specified by this document is intended to address Defense Nuclear Facilities Safety Board Recommendations 90-2 and 91-1, which call for the strengthening of DOE complex activities through the identification and application of relevant standards which supplement or exceed requirements mandated by DOE Orders. This RID applies to the activities, personnel, structures, systems, components, and programs involved in maintaining themore » facility and executing the mission of the High-Level Waste Storage Tank Farms.« less

  19. 21 CFR 1311.55 - Requirements for systems used to process digitally signed orders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... system must use either a user identification and password combination or biometric authentication to... and any other records required in part 1305 of this chapter, including any linked data. (10) The...) A system used to receive, verify, and create linked records for orders signed with a CSOS digital...

  20. Decontaminating the DOE-STD-3013 Inner Container to Meet 10-CFR-835 Appendix D Requirements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Martinez, H.E.; Nelson, T.O.; Rivera, Y.M.

    The United States Department of Energy (DOE) has published a standard that specifies the criteria for preparation and packaging of plutonium metals and oxides for safe long-term storage (DOE-STD-3013-96). This standard is followed for the packaging of materials resulting from the disassembly of nuclear weapons at Los Alamos National Laboratory under the Advanced Retirement and Integrated Extraction System (ARIES) project. Declassified plutonium metal or oxide material from the ARES project is packaged into doubly contained and welded type 304L stainless steel containers that comply with the DOE standard. The 3013-96 standard describes requirements for maximum contamination limits on the outermore » surface of the sealed inner container. These limits are 500 dpm per 100 cm2 for direct measurements and 20 dpm per 100 cm2 for removable contamination. For containers filled, welded, and handled inside a highly contaminated glovebox line, these limits are difficult to obtain. Simple handling within the line is demonstrated to contaminate surfaces from 10,000 to 10,000,000 dpm alpha per 100 cm2. To routinely achieve contamination levels below the maximum contamination levels specified by the 3013-96 standard within a processing operation, a decontamination step must be included. In the ARIES line, this decontamination step is an electrolytic process that produces a controlled uniform etch of the container surfaces. Decontamination of the 3013-96 compliant ARIES inner container is well demonstrated. Within 30 to 50 minutes electrolysis time, tixed contamination is reduced to hundreds of dpm generally occurring only at electrode contact points and welds. Removable contamination is routinely brought to non-detectable levels. The total process time for the cycle (includes electrolysis, rinse, and dry stages) is on the order of 1.5 to 2 hours per container. The ARIES inner container decontamination system highly automated and consists of a plumbing loop, electronic controls

  1. 20 CFR 10.609 - How does OWCP decide whether new evidence requires modification of the prior decision?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false How does OWCP decide whether new evidence requires modification of the prior decision? 10.609 Section 10.609 Employees' Benefits OFFICE OF WORKERS.... (b) A claims examiner who did not participate in making the contested decision will conduct the merit...

  2. 34 CFR 461.44 - How does a State request a waiver of the maintenance of effort requirement?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false How does a State request a waiver of the maintenance of effort requirement? 461.44 Section 461.44 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION...

  3. 34 CFR 461.44 - How does a State request a waiver of the maintenance of effort requirement?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false How does a State request a waiver of the maintenance of effort requirement? 461.44 Section 461.44 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION...

  4. 34 CFR 461.44 - How does a State request a waiver of the maintenance of effort requirement?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false How does a State request a waiver of the maintenance of effort requirement? 461.44 Section 461.44 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION...

  5. 34 CFR 461.44 - How does a State request a waiver of the maintenance of effort requirement?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false How does a State request a waiver of the maintenance of effort requirement? 461.44 Section 461.44 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION...

  6. 34 CFR 461.44 - How does a State request a waiver of the maintenance of effort requirement?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false How does a State request a waiver of the maintenance of effort requirement? 461.44 Section 461.44 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION...

  7. 32 CFR 555.9 - Reporting requirements for work in support of DOE.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... to the DOD-DOE Memorandum of Understanding will be reported to DAEN-RD for forwarding to DA and DOD... DOD-DOE Memorandum of Understanding will be prepared as a “Report on the Department of Defense... DOE fail to comply with the terms of the DOD-DOE Memorandum of Understanding or subordinate agreements...

  8. Review of Natural Phenomena Hazard (NPH) Assessments for the DOE Hanford Site

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Snow, Robert L.; Ross, Steven B.

    2011-09-15

    The purpose of this review is to assess the need for updating Natural Phenomena Hazard (NPH) assessments for the DOE's Hanford Site, as required by DOE Order 420.1B Chapter IV, Natural Phenomena Hazards Mitigation, based on significant changes in state-of-the-art NPH assessment methodology or site-specific information. This review is an update and expansion to the September 2010 review of PNNL-19751, Review of Natural Phenomena Hazard (NPH) Assessments for the Hanford 200 Areas (Non-Seismic).

  9. 22 CFR 66.4 - Availability of final opinions, orders, policies, interpretations, manuals and instructions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... is not an adjudicatory organization and therefore does not issue final opinions and orders made in... manuals and instructions to staff that affect any member of the public. (a) Deletion to protect privacy. To the extent required to prevent a clearly unwarranted invasion of personal privacy, NED may delete...

  10. 14 CFR 382.97 - To which aircraft does the requirement to provide boarding and deplaning assistance through the...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false To which aircraft does the requirement to... Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) SPECIAL REGULATIONS NONDISCRIMINATION ON THE BASIS OF DISABILITY IN AIR TRAVEL Boarding, Deplaning, and Connecting...

  11. 14 CFR 382.97 - To which aircraft does the requirement to provide boarding and deplaning assistance through the...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false To which aircraft does the requirement to... Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) SPECIAL REGULATIONS NONDISCRIMINATION ON THE BASIS OF DISABILITY IN AIR TRAVEL Boarding, Deplaning, and Connecting...

  12. 14 CFR 382.97 - To which aircraft does the requirement to provide boarding and deplaning assistance through the...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false To which aircraft does the requirement to... Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) SPECIAL REGULATIONS NONDISCRIMINATION ON THE BASIS OF DISABILITY IN AIR TRAVEL Boarding, Deplaning, and Connecting...

  13. Does spectroscopic evidence require two scattering layers in the Venus atmosphere.

    NASA Technical Reports Server (NTRS)

    Regas, J. L.; Boese, R. W.; Giver, L. P.; Miller, J. H.

    1973-01-01

    Comments on Hunt's (1972) conclusion that the phase variation of lines in the 7820- and 7883-A CO2 bands is due to the presence of two scattering layers in the Venusian atmosphere. It is shown that the increase of equivalent width with phase between 0 and 90 deg noted by Hunt in the data by Gray Young et al. (1971) does not necessarily require a two-layer model of scattering in the Venusian atmosphere and that this increase may be due to the strong backward lobe in the Venusian cloud phase function. Hunt, in a reply, notes that Regas et al. incorrectly use in their analysis Hansen's (1969) data which are for a homogeneous planetary atmosphere, while Hunt used an inhomogeneous model of the Venusian atmosphere. In addition, further evidence to support Hunt's claim for a multilayered structure of the upper Venusian clouds is presented.

  14. Material characterization for morphing purposes in order to match flight requirements

    NASA Astrophysics Data System (ADS)

    Geier, Sebastian; Kintscher, Markus; Heintze, Olaf; Wierach, Peter; Monner, Hans-Peter; Wiedemann, Martin

    2012-04-01

    Natural laminar flow is one of the challenging aims of the current aerospace research. Main reasons for the aerodynamic transition from laminar into turbulent flow focusing on the airfoil-structure is the aerodynamic shape and the surface roughness. The Institute of Composite Structures and Adaptive Systems at the German Aerospace Center in Braunschweig works on the optimization of the aerodynamic-loaded structure of future aircrafts in order to increase their efficiency. Providing wing structures suited for natural laminar flow is a step towards this goal. Regarding natural laminar flow, the structural design of the leading edge of a wing is of special interest. An approach for a gap-less leading edge was developed to provide a gap- and step-less high quality surface suited for natural laminar flow and to reduce slat noise. In a national project the first generation of the 3D full scale demonstrator was successfully tested in 2010. The prototype consists of several new technologies, opening up the issue of matching the long and challenging list of airworthiness requirements simultaneously. Therefore the developed composite structure was intensively tested for further modifications according to meet requirements for abrasion, impact and deicing basically. The former presented structure consists completely of glass-fiber-prepreg (GFRP-prepreg). New functions required the addition of a new material-mix, which has to fit into the manufacturing-chain of the composite structure. In addition the hybrid composites have to withstand high loadings, high bending-induced strains (1%) and environmentally influenced aging. Moreover hot-wet cycling tests are carried out for the basic GFRP-structure in order to simulate the long term behavior of the material under extrem conditions. The presented paper shows results of four-points-bending-tests of the most critical section of the morphing leading edge device. Different composite-hybrids are built up and processed. An experimental

  15. 21 CFR 1311.30 - Requirements for storing and using a private key for digitally signing orders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Requirements for storing and using a private key... Digital Certificates for Electronic Orders § 1311.30 Requirements for storing and using a private key for... and private key. (b) The certificate holder must provide FIPS-approved secure storage for the private...

  16. 41 CFR 102-118.25 - Does GSA still require my agency to submit its overall transportation policies for approval?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION TRANSPORTATION 118-TRANSPORTATION PAYMENT AND AUDIT General Introduction... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Does GSA still require...

  17. DOE explosives safety manual

    NASA Astrophysics Data System (ADS)

    1990-05-01

    The Department of Energy (DOE) policy requires that all activities be conducted in a manner that protects the safety of the public and provides a safe and healthful workplace for employees. DOE has also prescribed that all personnel be protected in any explosives operation undertaken. The level of safety provided shall be at least equivalent to that of the best industrial practice. The risk of death or serious injury shall be limited to the lowest practicable minimum. DOE and contractors shall continually review their explosives operations with the aim of achieving further refinements and improvements in safety practices and protective features. This manual describes the Department's explosive safety requirements applicable to operations involving the development, testing, handling, and processing of explosives or assemblies containing explosives. It is intended to reflect the state-of-the-art in explosives safety. In addition, it is essential that applicable criteria and requirements for implementing this policy be readily available and known to those responsible for conducting DOE programs. This document shall be periodically reviewed and updated to establish new requirements as appropriate. Users are requested to submit suggestions for improving the DOE Explosives Safety Manual through their appropriate Operations Office to the Office of Quality Programs.

  18. 21 CFR 1311.30 - Requirements for storing and using a private key for digitally signing orders.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Requirements for storing and using a private key... Certificates for Electronic Orders § 1311.30 Requirements for storing and using a private key for digitally... private key. (b) The certificate holder must provide FIPS-approved secure storage for the private key, as...

  19. 21 CFR 1311.30 - Requirements for storing and using a private key for digitally signing orders.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Requirements for storing and using a private key... Certificates for Electronic Orders § 1311.30 Requirements for storing and using a private key for digitally... private key. (b) The certificate holder must provide FIPS-approved secure storage for the private key, as...

  20. 21 CFR 1311.30 - Requirements for storing and using a private key for digitally signing orders.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Requirements for storing and using a private key... Certificates for Electronic Orders § 1311.30 Requirements for storing and using a private key for digitally... private key. (b) The certificate holder must provide FIPS-approved secure storage for the private key, as...

  1. 21 CFR 1311.30 - Requirements for storing and using a private key for digitally signing orders.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Requirements for storing and using a private key... Certificates for Electronic Orders § 1311.30 Requirements for storing and using a private key for digitally... private key. (b) The certificate holder must provide FIPS-approved secure storage for the private key, as...

  2. 20 CFR 655.840 - What are the requirements for a decision and order of the administrative law judge?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... order of the administrative law judge? 655.840 Section 655.840 Employees' Benefits EMPLOYMENT AND... requirements for a decision and order of the administrative law judge? (a) Within 60 calendar days after the... administrative law judge shall be inoperative unless and until the Secretary issues an order affirming the...

  3. 20 CFR 655.840 - What are the requirements for a decision and order of the administrative law judge?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... order of the administrative law judge? 655.840 Section 655.840 Employees' Benefits EMPLOYMENT AND... requirements for a decision and order of the administrative law judge? (a) Within 60 calendar days after the... administrative law judge shall be inoperative unless and until the Secretary issues an order affirming the...

  4. 20 CFR 655.840 - What are the requirements for a decision and order of the administrative law judge?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... order of the administrative law judge? 655.840 Section 655.840 Employees' Benefits EMPLOYMENT AND... requirements for a decision and order of the administrative law judge? (a) Within 60 calendar days after the... administrative law judge shall be inoperative unless and until the Secretary issues an order affirming the...

  5. 20 CFR 655.840 - What are the requirements for a decision and order of the administrative law judge?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... order of the administrative law judge? 655.840 Section 655.840 Employees' Benefits EMPLOYMENT AND... requirements for a decision and order of the administrative law judge? (a) Within 60 calendar days after the... administrative law judge shall be inoperative unless and until the Secretary issues an order affirming the...

  6. 21 CFR 1305.21 - Requirements for electronic orders.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 1311 of this chapter. (b) The following data fields must be included on an electronic order for... either the purchaser or the supplier). (8) The quantity in a single package or container. (9) The number of packages or containers of each item ordered. (c) An electronic order may include controlled...

  7. 21 CFR 1305.21 - Requirements for electronic orders.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 1311 of this chapter. (b) The following data fields must be included on an electronic order for... either the purchaser or the supplier). (8) The quantity in a single package or container. (9) The number of packages or containers of each item ordered. (c) An electronic order may include controlled...

  8. 21 CFR 1305.21 - Requirements for electronic orders.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 1311 of this chapter. (b) The following data fields must be included on an electronic order for... either the purchaser or the supplier). (8) The quantity in a single package or container. (9) The number of packages or containers of each item ordered. (c) An electronic order may include controlled...

  9. 36 CFR 902.51 - Records relating to matters that are required by Executive order to be kept secret.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... that are required by Executive order to be kept secret. 902.51 Section 902.51 Parks, Forests, and... order to be kept secret. Records relating to matters that are specifically authorized under criteria established by an Executive order to be kept secret in the interest of national defense or foreign policy...

  10. 36 CFR 902.51 - Records relating to matters that are required by Executive order to be kept secret.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... that are required by Executive order to be kept secret. 902.51 Section 902.51 Parks, Forests, and... order to be kept secret. Records relating to matters that are specifically authorized under criteria established by an Executive order to be kept secret in the interest of national defense or foreign policy...

  11. 36 CFR 902.51 - Records relating to matters that are required by Executive order to be kept secret.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... that are required by Executive order to be kept secret. 902.51 Section 902.51 Parks, Forests, and... order to be kept secret. Records relating to matters that are specifically authorized under criteria established by an Executive order to be kept secret in the interest of national defense or foreign policy...

  12. 36 CFR 902.51 - Records relating to matters that are required by Executive order to be kept secret.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... that are required by Executive order to be kept secret. 902.51 Section 902.51 Parks, Forests, and... order to be kept secret. Records relating to matters that are specifically authorized under criteria established by an Executive order to be kept secret in the interest of national defense or foreign policy...

  13. Rethinking pedagogy for second-order differential equations: a simplified approach to understanding well-posed problems

    NASA Astrophysics Data System (ADS)

    Tisdell, Christopher C.

    2017-07-01

    Knowing an equation has a unique solution is important from both a modelling and theoretical point of view. For over 70 years, the approach to learning and teaching 'well posedness' of initial value problems (IVPs) for second- and higher-order ordinary differential equations has involved transforming the problem and its analysis to a first-order system of equations. We show that this excursion is unnecessary and present a direct approach regarding second- and higher-order problems that does not require an understanding of systems.

  14. 21 CFR 1305.03 - Distributions requiring a Form 222 or a digitally signed electronic order.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Distributions requiring a Form 222 or a digitally signed electronic order. Either a DEA Form 222 or its... laboratory or its agent approved by DEA. (d) Delivery from a central fill pharmacy, as defined in § 1300.01(b...

  15. 21 CFR 1305.03 - Distributions requiring a Form 222 or a digitally signed electronic order.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Distributions requiring a Form 222 or a digitally signed electronic order. Either a DEA Form 222 or its... laboratory or its agent approved by DEA. (d) Delivery from a central fill pharmacy, as defined in § 1300.01(b...

  16. The effects of nidopallium caudolaterale inactivation on serial-order behaviour in pigeons (Columba livia).

    PubMed

    Johnston, Melissa Jane; Clarkson, Andrew N; Gowing, Emma K; Scarf, Damian; Colombo, Mike

    2018-06-06

    Serial-order behaviour is the ability to complete a sequence of responses in a predetermined order to achieve a reward. In birds, serial-order behaviour is thought to be impaired by damage to the nidopallium caudolaterale (NCL). In the current study, we examined the role of the NCL in serial-order behaviour by training pigeons on a 4-item serial-order task and a go/no-go discrimination task. Following training, pigeons were received infusions of 1μl of either tetrodotoxin (TTX) or saline. Saline infusions had no impact on serial-order behaviour whereas TTX infusions resulted in a significant decrease in performance. The serial-order impairments, however, were not the results of errors of any specific error at any specific list item. With respect to the go/no-go discrimination task, saline infusions also had no impact on performance whereas TTX infusions impaired pigeons' discrimination abilities. Given the impairments on the go/no-go discrimination task, which does not require processing of serial-order information, we tentatively conclude that damage to the NCL does not impair serial-order behaviour per se, but rather results in a more generalised impairment that may impact performance across a range of tasks.

  17. The Clean Air Act Amendments of 1990: Hazardous Air Pollutant Requirements and the DOE Clean Coal Technology Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moskowitz, P.D.; DePhillips, M.; Fthenakis, V.M.

    1991-12-31

    The purpose of the US Department of Energy -- Office of Fossil Energy (DOE FE) Clean Coal Technology Program (CCTP) is to provide the US energy marketplace with advanced, efficient, and environmentally sound coal-based technologies. The design, construction, and operation of Clean Coal Technology Demonstration Projects (CCTDP) will generate data needed to make informed, confident decisions on the commercial readiness of these technologies. These data also will provide information needed to ensure a proactive response by DOE and its industrial partners to the establishment of new regulations or a reactive response to existing regulations promulgated by the US Environmental Protectionmore » Agency (EPA). The objectives of this paper are to: (1) Present a preliminary examination of the potential implications of the Clean Air Act Amendments (CAAA) -- Title 3 Hazardous Air Pollutant requirements to the commercialization of CCTDP; and (2) help define options available to DOE and its industrial partners to respond to this newly enacted Legislation.« less

  18. The Clean Air Act Amendments of 1990: Hazardous Air Pollutant Requirements and the DOE Clean Coal Technology Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moskowitz, P.D.; DePhillips, M.; Fthenakis, V.M.

    1991-01-01

    The purpose of the US Department of Energy -- Office of Fossil Energy (DOE FE) Clean Coal Technology Program (CCTP) is to provide the US energy marketplace with advanced, efficient, and environmentally sound coal-based technologies. The design, construction, and operation of Clean Coal Technology Demonstration Projects (CCTDP) will generate data needed to make informed, confident decisions on the commercial readiness of these technologies. These data also will provide information needed to ensure a proactive response by DOE and its industrial partners to the establishment of new regulations or a reactive response to existing regulations promulgated by the US Environmental Protectionmore » Agency (EPA). The objectives of this paper are to: (1) Present a preliminary examination of the potential implications of the Clean Air Act Amendments (CAAA) -- Title 3 Hazardous Air Pollutant requirements to the commercialization of CCTDP; and (2) help define options available to DOE and its industrial partners to respond to this newly enacted Legislation.« less

  19. Requirements for clinical information modelling tools.

    PubMed

    Moreno-Conde, Alberto; Jódar-Sánchez, Francisco; Kalra, Dipak

    2015-07-01

    This study proposes consensus requirements for clinical information modelling tools that can support modelling tasks in medium/large scale institutions. Rather than identify which functionalities are currently available in existing tools, the study has focused on functionalities that should be covered in order to provide guidance about how to evolve the existing tools. After identifying a set of 56 requirements for clinical information modelling tools based on a literature review and interviews with experts, a classical Delphi study methodology was applied to conduct a two round survey in order to classify them as essential or recommended. Essential requirements are those that must be met by any tool that claims to be suitable for clinical information modelling, and if we one day have a certified tools list, any tool that does not meet essential criteria would be excluded. Recommended requirements are those more advanced requirements that may be met by tools offering a superior product or only needed in certain modelling situations. According to the answers provided by 57 experts from 14 different countries, we found a high level of agreement to enable the study to identify 20 essential and 21 recommended requirements for these tools. It is expected that this list of identified requirements will guide developers on the inclusion of new basic and advanced functionalities that have strong support by end users. This list could also guide regulators in order to identify requirements that could be demanded of tools adopted within their institutions. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  20. Higher order thinking skills competencies required by outcomes-based education from learners.

    PubMed

    Chabeli, M M

    2006-08-01

    Outcomes-Based Education (OBE) brought about a significant paradigm shift in the education and training of learners in South Africa. OBE requires a shift from focusing on the teacher input (instruction offerings or syllabuses expressed in terms of content), to focusing on learner outcomes. OBE is moving away from 'transmission' models to constructivistic, learner-centered models that put emphasis on learning as an active process (Nieburh, 1996:30). Teachers act as facilitators and mediators of learning (Norms and Standards, Government Gazette vol 415, no 20844 of 2000). Facilitators are responsible to create the environment that is conducive for learners to construct their own knowledge, skills and values through interaction (Peters, 2000). The first critical cross-field outcome accepted by the South African Qualification Framework (SAQA) is that learners should be able to identify and solve problems by using critical and creative thinking skills. This paper seeks to explore some higher order thinking skills competencies required by OBE from learners such as critical thinking, reflective thinking, creative thinking, dialogic / dialectic thinking, decision making, problem solving and emotional intelligence and their implications in facilitating teaching and learning from the theoretical perspective. The philosophical underpinning of these higher order thinking skills is described to give direction to the study. It is recommended that a study focusing on the assessment of these intellectual concepts be made. The study may be qualitative, quantitative or mixed methods in nature (Creswell 2005).

  1. Interpretation of Do Not Attempt Resuscitation Orders for Children Requiring Anesthesia and Surgery.

    PubMed

    Fallat, Mary E; Hardy, Courtney

    2018-05-01

    This clinical report addresses the topic of pre-existing do not attempt resuscitation or limited resuscitation orders for children and adolescents undergoing anesthesia and surgery. Pertinent considerations for the clinician include the rights of children, decision-making by parents or legally approved representatives, the process of informed consent, and the roles of surgeon and anesthesiologist. A process of re-evaluation of the do not attempt resuscitation orders, called "required reconsideration," should be incorporated into the process of informed consent for surgery and anesthesia, distinguishing between goal-directed and procedure-directed approaches. The child's individual needs are best served by allowing the parent or legally approved representative and involved clinicians to consider whether full resuscitation, limitations based on procedures, or limitations based on goals is most appropriate. Copyright © 2018 by the American Academy of Pediatrics.

  2. 25 CFR 224.41 - When does the Secretary require agreement of more than one tribe to approve a TERA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false When does the Secretary require agreement of more than one tribe to approve a TERA? 224.41 Section 224.41 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT...

  3. Tank vapor mitigation requirements for Hanford Tank Farms

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rakestraw, L.D.

    1994-11-15

    Westinghouse Hanford Company has contracted Los Alamos Technical Associates to listing of vapors and aerosols that are or may be emitted from the High Level Waste (HLW) tanks at Hanford. Mitigation requirements under Federal and State law, as well as DOE Orders, are included in the listing. The lists will be used to support permitting activities relative to tank farm ventilation system up-grades. This task is designated Task 108 under MJB-SWV-312057 and is an extension of efforts begun under Task 53 of Purchase Order MPB-SVV-03291 5 for Mechanical Engineering Support. The results of that task, which covered only thirty-nine tanks,more » are repeated here to provide a single source document for vapor mitigation requirements for all 177 HLW tanks.« less

  4. Fast calibration of high-order adaptive optics systems.

    PubMed

    Kasper, Markus; Fedrigo, Enrico; Looze, Douglas P; Bonnet, Henri; Ivanescu, Liviu; Oberti, Sylvain

    2004-06-01

    We present a new method of calibrating adaptive optics systems that greatly reduces the required calibration time or, equivalently, improves the signal-to-noise ratio. The method uses an optimized actuation scheme with Hadamard patterns and does not scale with the number of actuators for a given noise level in the wavefront sensor channels. It is therefore highly desirable for high-order systems and/or adaptive secondary systems on a telescope without a Gregorian focal plane. In the latter case, the measurement noise is increased by the effects of the turbulent atmosphere when one is calibrating on a natural guide star.

  5. 36 CFR § 902.51 - Records relating to matters that are required by Executive order to be kept secret.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... that are required by Executive order to be kept secret. § 902.51 Section § 902.51 Parks, Forests, and... order to be kept secret. Records relating to matters that are specifically authorized under criteria established by an Executive order to be kept secret in the interest of national defense or foreign policy...

  6. 21 CFR 1305.21 - Requirements for electronic orders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) To be valid, the purchaser must sign an electronic order for a Schedule I or II controlled substance... 1311 of this chapter. (b) The following data fields must be included on an electronic order for... either the purchaser or the supplier). (8) The quantity in a single package or container. (9) The number...

  7. 21 CFR 1305.21 - Requirements for electronic orders.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) To be valid, the purchaser must sign an electronic order for a Schedule I or II controlled substance... 1311 of this chapter. (b) The following data fields must be included on an electronic order for... either the purchaser or the supplier). (8) The quantity in a single package or container. (9) The number...

  8. Protein synthesis in the basolateral amygdala complex is required for consolidation of a first-order fear memory, but not for consolidation of a higher-order fear memory.

    PubMed

    Leidl, Dana M; Lay, Belinda P P; Chakouch, Cassandra; Westbrook, R Frederick; Holmes, Nathan M

    2018-04-12

    The present series of experiments pursued our recent findings that consolidation of a second-order fear memory requires neuronal activity, but not de novo protein synthesis, in the basolateral amygdala complex (BLA). It used a modified second-order conditioning protocol in which rats were exposed to S1-shock pairings in stage 1 and pairings of the serial S2-S1 compound and shock in stage 2. Experiment 1 showed that responding (freezing) to S2 in this protocol is conditional on its compounding with S1 in stage 2 (Experiment 1), and therefore, the result of associative formation. The remaining experiments then showed that the protein synthesis requirement for consolidation of new learning about S2 varied with the training afforded S1. When S1 was trained in stage 1 and present in stage 2, consolidation of the new S2 fear memory was unaffected by pre- or post-stage 2 infusions of the protein synthesis inhibitor, cycloheximide, into the BLA (Experiments 2 and 5). This result was observed independently of the number of S1-shock pairings in stage 1 (even a single pairing produced the result), and alongside demonstrations that cycloheximide infusions disrupt consolidation of a first-order fear memory (Experiments 2 and 5). However, when S1 was not conditioned in stage 1 (Experiment 3) or was omitted from conditioning in stage 2 (Experiment 4), consolidation of the new S2 fear memory was disrupted by post-stage 2 cycloheximide infusions into the BLA. These results were taken to imply that the consolidation of a higher-order fear memory exploits molecular events associated with consolidation of a reactivated first-order fear memory; hence it occurs independently of de novo protein synthesis in the BLA. Alternatively, the nature of the association formed in higher-order conditioning may be such as to not require de novo protein synthesis for its consolidation. Copyright © 2018 Elsevier Inc. All rights reserved.

  9. Policies and practices pertaining to the selection, qualification requirements, and training programs for nuclear-reactor operating personnel at the Oak Ridge National Laboratory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Culbert, W.H.

    1985-10-01

    This document describes the policies and practices of the Oak Ridge National Laboratory (ORNL) regarding the selection of and training requirements for reactor operating personnel at the Laboratory's nuclear-reactor facilities. The training programs, both for initial certification and for requalification, are described and provide the guidelines for ensuring that ORNL's research reactors are operated in a safe and reliable manner by qualified personnel. This document gives an overview of the reactor facilities and addresses the various qualifications, training, testing, and requalification requirements stipulated in DOE Order 5480.1A, Chapter VI (Safety of DOE-Owned Reactors); it is intended to be in compliancemore » with this DOE Order, as applicable to ORNL facilities. Included also are examples of the documentation maintained amenable for audit.« less

  10. 31 CFR 30.6 - Q-6: How does a TARP recipient comply with the requirement under § 30.4 (Q-4) of this part that...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false Q-6: How does a TARP recipient comply with the requirement under § 30.4 (Q-4) of this part that the compensation committee discuss, evaluate... TARP STANDARDS FOR COMPENSATION AND CORPORATE GOVERNANCE § 30.6 Q-6: How does a TARP recipient comply...

  11. 31 CFR 30.6 - Q-6: How does a TARP recipient comply with the requirement under § 30.4 (Q-4) of this part that...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false Q-6: How does a TARP recipient comply with the requirement under § 30.4 (Q-4) of this part that the compensation committee discuss, evaluate... TARP STANDARDS FOR COMPENSATION AND CORPORATE GOVERNANCE § 30.6 Q-6: How does a TARP recipient comply...

  12. 31 CFR 30.6 - Q-6: How does a TARP recipient comply with the requirement under § 30.4 (Q-4) of this part that...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Q-6: How does a TARP recipient comply with the requirement under § 30.4 (Q-4) of this part that the compensation committee discuss, evaluate... TARP STANDARDS FOR COMPENSATION AND CORPORATE GOVERNANCE § 30.6 Q-6: How does a TARP recipient comply...

  13. 31 CFR 30.6 - Q-6: How does a TARP recipient comply with the requirement under § 30.4 (Q-4) of this part that...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false Q-6: How does a TARP recipient comply with the requirement under § 30.4 (Q-4) of this part that the compensation committee discuss, evaluate... TARP STANDARDS FOR COMPENSATION AND CORPORATE GOVERNANCE § 30.6 Q-6: How does a TARP recipient comply...

  14. 31 CFR 30.5 - Q-5: How does a TARP recipient comply with the requirements under § 30.4 (Q-4) of this part that...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false Q-5: How does a TARP recipient comply with the requirements under § 30.4 (Q-4) of this part that the compensation committee discuss... STANDARDS FOR COMPENSATION AND CORPORATE GOVERNANCE § 30.5 Q-5: How does a TARP recipient comply with the...

  15. 31 CFR 30.5 - Q-5: How does a TARP recipient comply with the requirements under § 30.4 (Q-4) of this part that...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false Q-5: How does a TARP recipient comply with the requirements under § 30.4 (Q-4) of this part that the compensation committee discuss... STANDARDS FOR COMPENSATION AND CORPORATE GOVERNANCE § 30.5 Q-5: How does a TARP recipient comply with the...

  16. 31 CFR 30.5 - Q-5: How does a TARP recipient comply with the requirements under § 30.4 (Q-4) of this part that...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false Q-5: How does a TARP recipient comply with the requirements under § 30.4 (Q-4) of this part that the compensation committee discuss... STANDARDS FOR COMPENSATION AND CORPORATE GOVERNANCE § 30.5 Q-5: How does a TARP recipient comply with the...

  17. 16 CFR 1025.39 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... provide other information and granting immunity. 1025.39 Section 1025.39 Commercial Practices CONSUMER... Process § 1025.39 Orders requiring witnesses to testify or provide other information and granting immunity... witness or deponent to testify or provide other information upon being granted immunity from prosecution...

  18. 16 CFR 1025.39 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... provide other information and granting immunity. 1025.39 Section 1025.39 Commercial Practices CONSUMER... Process § 1025.39 Orders requiring witnesses to testify or provide other information and granting immunity... witness or deponent to testify or provide other information upon being granted immunity from prosecution...

  19. 16 CFR 1025.39 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... provide other information and granting immunity. 1025.39 Section 1025.39 Commercial Practices CONSUMER... Process § 1025.39 Orders requiring witnesses to testify or provide other information and granting immunity... witness or deponent to testify or provide other information upon being granted immunity from prosecution...

  20. 16 CFR 2.15 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... provide other information and granting immunity. 2.15 Section 2.15 Commercial Practices FEDERAL TRADE... and granting immunity. (a) The Bureau Director, Deputy Directors, and Assistant Directors in the... issuance of an order requiring a witness to testify or provide other information granting immunity under...

  1. 16 CFR 1025.39 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... provide other information and granting immunity. 1025.39 Section 1025.39 Commercial Practices CONSUMER... Process § 1025.39 Orders requiring witnesses to testify or provide other information and granting immunity... witness or deponent to testify or provide other information upon being granted immunity from prosecution...

  2. 16 CFR 2.15 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... provide other information and granting immunity. 2.15 Section 2.15 Commercial Practices FEDERAL TRADE... and granting immunity. (a) The Bureau Director, Deputy Directors, and Assistant Directors in the... issuance of an order requiring a witness to testify or provide other information granting immunity under...

  3. 16 CFR 2.15 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... provide other information and granting immunity. 2.15 Section 2.15 Commercial Practices FEDERAL TRADE... and granting immunity. (a) The Bureau Director, Deputy Directors, and Assistant Directors in the... issuance of an order requiring a witness to testify or provide other information granting immunity under...

  4. 16 CFR 2.15 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... provide other information and granting immunity. 2.15 Section 2.15 Commercial Practices FEDERAL TRADE... and granting immunity. (a) The Bureau Director, Deputy Directors, and Assistant Directors in the... issuance of an order requiring a witness to testify or provide other information granting immunity under...

  5. Quantum correlations with no causal order

    PubMed Central

    Oreshkov, Ognyan; Costa, Fabio; Brukner, Časlav

    2012-01-01

    The idea that events obey a definite causal order is deeply rooted in our understanding of the world and at the basis of the very notion of time. But where does causal order come from, and is it a necessary property of nature? Here, we address these questions from the standpoint of quantum mechanics in a new framework for multipartite correlations that does not assume a pre-defined global causal structure but only the validity of quantum mechanics locally. All known situations that respect causal order, including space-like and time-like separated experiments, are captured by this framework in a unified way. Surprisingly, we find correlations that cannot be understood in terms of definite causal order. These correlations violate a 'causal inequality' that is satisfied by all space-like and time-like correlations. We further show that in a classical limit causal order always arises, which suggests that space-time may emerge from a more fundamental structure in a quantum-to-classical transition. PMID:23033068

  6. Order reduction of z-transfer functions via multipoint Jordan continued-fraction expansion

    NASA Technical Reports Server (NTRS)

    Lee, Ying-Chin; Hwang, Chyi; Shieh, Leang S.

    1992-01-01

    The order reduction problem of z-transfer functions is solved by using the multipoint Jordan continued-fraction expansion (MJCFE) technique. An efficient algorithm that does not require the use of complex algebra is presented for obtaining an MJCFE from a stable z-transfer function with expansion points selected from the unit circle and/or the positive real axis of the z-plane. The reduced-order models are exactly the multipoint Pade approximants of the original system and, therefore, they match the (weighted) time-moments of the impulse response and preserve the frequency responses of the system at some characteristic frequencies, such as gain crossover frequency, phase crossover frequency, bandwidth, etc.

  7. 49 CFR 511.39 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... other information and granting immunity. 511.39 Section 511.39 Transportation Other Regulations Relating... testify or provide other information and granting immunity. (a) A party who desires the issuance of an order requiring a witness to testify or provide other information upon being granted immunity from...

  8. 49 CFR 511.39 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... other information and granting immunity. 511.39 Section 511.39 Transportation Other Regulations Relating... testify or provide other information and granting immunity. (a) A party who desires the issuance of an order requiring a witness to testify or provide other information upon being granted immunity from...

  9. 49 CFR 511.39 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... other information and granting immunity. 511.39 Section 511.39 Transportation Other Regulations Relating... testify or provide other information and granting immunity. (a) A party who desires the issuance of an order requiring a witness to testify or provide other information upon being granted immunity from...

  10. 49 CFR 511.39 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... other information and granting immunity. 511.39 Section 511.39 Transportation Other Regulations Relating... testify or provide other information and granting immunity. (a) A party who desires the issuance of an order requiring a witness to testify or provide other information upon being granted immunity from...

  11. 49 CFR 511.39 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... other information and granting immunity. 511.39 Section 511.39 Transportation Other Regulations Relating... testify or provide other information and granting immunity. (a) A party who desires the issuance of an order requiring a witness to testify or provide other information upon being granted immunity from...

  12. Parallel Conjugate Gradient: Effects of Ordering Strategies, Programming Paradigms, and Architectural Platforms

    NASA Technical Reports Server (NTRS)

    Oliker, Leonid; Heber, Gerd; Biswas, Rupak

    2000-01-01

    The Conjugate Gradient (CG) algorithm is perhaps the best-known iterative technique to solve sparse linear systems that are symmetric and positive definite. A sparse matrix-vector multiply (SPMV) usually accounts for most of the floating-point operations within a CG iteration. In this paper, we investigate the effects of various ordering and partitioning strategies on the performance of parallel CG and SPMV using different programming paradigms and architectures. Results show that for this class of applications, ordering significantly improves overall performance, that cache reuse may be more important than reducing communication, and that it is possible to achieve message passing performance using shared memory constructs through careful data ordering and distribution. However, a multi-threaded implementation of CG on the Tera MTA does not require special ordering or partitioning to obtain high efficiency and scalability.

  13. 16 CFR 3.39 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... provide other information and granting immunity. 3.39 Section 3.39 Commercial Practices FEDERAL TRADE... granting immunity. (a) Where Commission complaint counsel desire the issuance of an order requiring a witness or deponent to testify or provide other information and granting immunity under 18 U.S.C. 6002...

  14. 16 CFR 3.39 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... provide other information and granting immunity. 3.39 Section 3.39 Commercial Practices FEDERAL TRADE... granting immunity. (a) Where Commission complaint counsel desire the issuance of an order requiring a witness or deponent to testify or provide other information and granting immunity under 18 U.S.C. 6002...

  15. 12 CFR 1080.12 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... provide other information and granting immunity. 1080.12 Section 1080.12 Banks and Banking BUREAU OF... testify or provide other information and granting immunity. (a) The Assistant Director of the Division of... issuance of an order requiring a witness to testify or provide other information granting immunity under 18...

  16. 16 CFR 3.39 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... provide other information and granting immunity. 3.39 Section 3.39 Commercial Practices FEDERAL TRADE... granting immunity. (a) Where Commission complaint counsel desire the issuance of an order requiring a witness or deponent to testify or provide other information and granting immunity under 18 U.S.C. 6002...

  17. 16 CFR 3.39 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... provide other information and granting immunity. 3.39 Section 3.39 Commercial Practices FEDERAL TRADE... granting immunity. (a) Where Commission complaint counsel desire the issuance of an order requiring a witness or deponent to testify or provide other information and granting immunity under 18 U.S.C. 6002...

  18. 16 CFR 3.39 - Orders requiring witnesses to testify or provide other information and granting immunity.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... provide other information and granting immunity. 3.39 Section 3.39 Commercial Practices FEDERAL TRADE... granting immunity. (a) Where Commission complaint counsel desire the issuance of an order requiring a witness or deponent to testify or provide other information and granting immunity under 18 U.S.C. 6002...

  19. 77 FR 16091 - Order Modifying Licenses With Regard to Requirements for Mitigation Strategies for Beyond-Design...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-19

    .... (as shown in Attachment 1)) EA-12-049 I The Licensees and construction permits (CP) holders \\1..., ``Licenses, Certifications, and Approvals for Nuclear Power Plants.'' \\1\\ CP holders, as used in this Order... that additional requirements must be imposed on Licensees or CP holders to increase the [[Page 16092...

  20. Problem Order Implications for Learning

    ERIC Educational Resources Information Center

    Li, Nan; Cohen, William W.; Koedinger, Kenneth R.

    2013-01-01

    The order of problems presented to students is an important variable that affects learning effectiveness. Previous studies have shown that solving problems in a blocked order, in which all problems of one type are completed before the student is switched to the next problem type, results in less effective performance than does solving the problems…

  1. Does the Chemical Diversity of the Order Haplosclerida (Phylum Porifera: Class Demospongia) Fit with Current Taxonomic Classification?

    PubMed

    Tribalat, Marie-Aude; Marra, Maria V; McCormack, Grace P; Thomas, Olivier P

    2016-06-01

    Sponges and their associated microbiota are well known to produce a large diversity of natural products, also called specialized metabolites. In addition to their potential use in the pharmaceutical industry, these rather species-specific compounds may help in the classification of some particular sponge groups. We review herein compounds isolated from haplosclerid sponges (Class Demospongia, Order Haplosclerida) in order to help in the revision of this large group of marine invertebrates. We focus only on 3-alkylpyridine derivatives and polyacetylenic compounds, as these two groups of natural products are characteristic of haplosclerid species and are highly diverse. A close collaboration between chemists and biologists is required in order to fully apply chemotaxonomical approaches, and whenever possible biological data should include morphological and molecular data and some insight into their microbial abundance. Georg Thieme Verlag KG Stuttgart · New York.

  2. Civil Commitment for Opioid and Other Substance Use Disorders: Does It Work?

    PubMed

    Jain, Abhishek; Christopher, Paul; Appelbaum, Paul S

    2018-04-01

    Many states are turning to civil commitment for substance use disorders as a potential solution to address rising rates of overdose deaths. Civil commitment allows family members or others to seek court-ordered involuntary treatment for a substance-abusing person. In contrast to mandatory treatment ordered by drug courts, civil commitment does not require involvement with the criminal justice system. Although these laws are understandably appealing, statutes and their implementation are highly variable, ethical concerns about deprivation of liberty continue to be raised, and outcome data are limited and often not generalizable. Above all, more studies are needed to determine effectiveness.

  3. Scalable Replay with Partial-Order Dependencies for Message-Logging Fault Tolerance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lifflander, Jonathan; Meneses, Esteban; Menon, Harshita

    2014-09-22

    Deterministic replay of a parallel application is commonly used for discovering bugs or to recover from a hard fault with message-logging fault tolerance. For message passing programs, a major source of overhead during forward execution is recording the order in which messages are sent and received. During replay, this ordering must be used to deterministically reproduce the execution. Previous work in replay algorithms often makes minimal assumptions about the programming model and application in order to maintain generality. However, in many cases, only a partial order must be recorded due to determinism intrinsic in the code, ordering constraints imposed bymore » the execution model, and events that are commutative (their relative execution order during replay does not need to be reproduced exactly). In this paper, we present a novel algebraic framework for reasoning about the minimum dependencies required to represent the partial order for different concurrent orderings and interleavings. By exploiting this theory, we improve on an existing scalable message-logging fault tolerance scheme. The improved scheme scales to 131,072 cores on an IBM BlueGene/P with up to 2x lower overhead than one that records a total order.« less

  4. Parent-Child Quality Time: Does Birth Order Matter?

    ERIC Educational Resources Information Center

    Price, Joseph

    2008-01-01

    Using data from the American Time Use Survey, I find that a first-born child receives 20-30 more minutes of quality time each day with his or her parent than a second-born child of the same age from a similar family. The birth-order difference results from parents giving roughly equal time to each child at any point in time while the amount of…

  5. 77 FR 50680 - Notice of Orders Granting Applications and an Order Vacating Authority To Import and Export...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... June 2012 AGENCY: Office of Fossil Energy, Department of Energy (DOE). ACTION: Notice of orders. FE... & GAS COMPANY, 12-69-NG LLC. MONETA ENERGY SERVICES, LTD 12-70-NG SUMMARY: The Office of Fossil Energy....fossil.energy.gov/programs/gasregulation/authorizations/Orders-2012.html . They are also available for...

  6. Commercial Decommissioning at DOE's Rocky Flats

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Freiboth, C.; Sandlin, N.; Schubert, A.

    2002-02-25

    Due in large part to the number of nuclear facilities that make up the DOE complex, DOE-EM work has historically been paperwork intensive and driven by extensive regulations. Requirements for non-nuclear facilities are often grouped with those of nuclear facilities, driving up costs. Kaiser-Hill was interested in applying a commercial model to demolition of these facilities and wanted to apply necessary and sufficient standards to the work activities, but avoid applying unnecessary requirements. Faced with demolishing hundreds of uncontaminated or non-radiologically contaminated facilities, Kaiser-Hill has developed a subcontracting strategy to drastically reduce the cost of demolishing these facilities at Rockymore » Flats. Aiming to tailor the demolition approach of such facilities to more closely follow commercial practices, Kaiser-Hill recently released a Request for Proposals (RFP) for the demolition of the site's former central administration facility. The RFP significantly reduced requirements for compliance with specific DOE directives. Instead, the RFP required subcontractors to comply with health and safety requirements commonly found in the demolition of similar facilities in a commercial setting. This resulted in a number of bids from companies who have normally not bid on DOE work previously and at a reduced cost over previous approaches. This paper will discuss the details of this subcontracting strategy.« less

  7. Ordered short-term memory differs in signers and speakers: Implications for models of short-term memory

    PubMed Central

    Bavelier, Daphne; Newport, Elissa L.; Hall, Matt; Supalla, Ted; Boutla, Mrim

    2008-01-01

    Capacity limits in linguistic short-term memory (STM) are typically measured with forward span tasks in which participants are asked to recall lists of words in the order presented. Using such tasks, native signers of American Sign Language (ASL) exhibit smaller spans than native speakers (Boutla, Supalla, Newport, & Bavelier, 2004). Here, we test the hypothesis that this population difference reflects differences in the way speakers and signers maintain temporal order information in short-term memory. We show that native signers differ from speakers on measures of short-term memory that require maintenance of temporal order of the tested materials, but not on those in which temporal order is not required. In addition, we show that, in a recall task with free order, bilingual subjects are more likely to recall in temporal order when using English than ASL. We conclude that speakers and signers do share common short-term memory processes. However, whereas short-term memory for spoken English is predominantly organized in terms of temporal order, we argue that this dimension does not play as great a role in signers’ short-term memory. Other factors that may affect STM processes in signers are discussed. PMID:18083155

  8. IDC Re-Engineering Phase 2 System Requirements Document V1.3.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Harris, James M.; Burns, John F.; Satpathi, Meara Allena

    2015-12-01

    This System Requirements Document (SRD) defines waveform data processing requirements for the International Data Centre (IDC) of the Comprehensive Nuclear Test Ban Treaty Organization (CTBTO). The IDC applies, on a routine basis, automatic processing methods and interactive analysis to raw International Monitoring System (IMS) data in order to produce, archive, and distribute standard IDC products on behalf of all States Parties. The routine processing includes characterization of events with the objective of screening out events considered to be consistent with natural phenomena or non-nuclear, man-made phenomena. This document does not address requirements concerning acquisition, processing and analysis of radionuclide datamore » but includes requirements for the dissemination of radionuclide data and products.« less

  9. IDC Re-Engineering Phase 2 System Requirements Document Version 1.4

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Harris, James M.; Burns, John F.; Satpathi, Meara Allena

    This System Requirements Document (SRD) defines waveform data processing requirements for the International Data Centre (IDC) of the Comprehensive Nuclear Test Ban Treaty Organization (CTBTO). The IDC applies, on a routine basis, automatic processing methods and interactive analysis to raw International Monitoring System (IMS) data in order to produce, archive, and distribute standard IDC products on behalf of all States Parties. The routine processing includes characterization of events with the objective of screening out events considered to be consistent with natural phenomena or non-nuclear, man-made phenomena. This document does not address requirements concerning acquisition, processing and analysis of radionuclide data,more » but includes requirements for the dissemination of radionuclide data and products.« less

  10. 49 CFR 23.77 - Does this part preempt local requirements?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Section 23.77 Transportation Office of the Secretary of Transportation PARTICIPATION OF DISADVANTAGED BUSINESS ENTERPRISE IN AIRPORT CONCESSIONS Other Provisions § 23.77 Does this part preempt local...) You must clearly identify any State or local law, regulation, or policy pertaining to minority, women...

  11. Spatial attention does not require preattentive grouping.

    PubMed

    Vecera, S P; Behrmann, M

    1997-01-01

    Does spatial attention follow a full preattentive analysis of the visual field, or can attention select from ungrouped regions of the visual field? We addressed this question by testing an apperceptive agnosic patient, J. W., in tasks involving both spatial selection and preattentive grouping. Results suggest that J.W. had intact spatial attention: He was faster to detect targets appearing at cued location relative to targets appearing at uncued locations. However, his preattentive processes were severely disrupted. Gestalt grouping and symmetry perception, both thought to involve preattentive processes, were impaired in J. W. Also, he could not use gestalt grouping cues to guide spatial attention. These results suggest that spatial attention is not completely dependent on preattentive grouping processes. We argue that preattentive grouping processes and spatial attention may mutually constrain one another in guiding the attentional selection of visual stimuli but that these 2 processes are isolated from one another.

  12. Higher-order neural network software for distortion invariant object recognition

    NASA Technical Reports Server (NTRS)

    Reid, Max B.; Spirkovska, Lilly

    1991-01-01

    The state-of-the-art in pattern recognition for such applications as automatic target recognition and industrial robotic vision relies on digital image processing. We present a higher-order neural network model and software which performs the complete feature extraction-pattern classification paradigm required for automatic pattern recognition. Using a third-order neural network, we demonstrate complete, 100 percent accurate invariance to distortions of scale, position, and in-plate rotation. In a higher-order neural network, feature extraction is built into the network, and does not have to be learned. Only the relatively simple classification step must be learned. This is key to achieving very rapid training. The training set is much smaller than with standard neural network software because the higher-order network only has to be shown one view of each object to be learned, not every possible view. The software and graphical user interface run on any Sun workstation. Results of the use of the neural software in autonomous robotic vision systems are presented. Such a system could have extensive application in robotic manufacturing.

  13. A nonrecursive 'Order N' preconditioned conjugate gradient/range space formulation of MDOF dynamics

    NASA Technical Reports Server (NTRS)

    Kurdila, A. J.; Menon, R.; Sunkel, John

    1991-01-01

    This paper addresses the requirements of present-day mechanical system simulations of algorithms that induce parallelism on a fine scale and of transient simulation methods which must be automatically load balancing for a wide collection of system topologies and hardware configurations. To this end, a combination range space/preconditioned conjugage gradient formulation of multidegree-of-freedon dynamics is developed, which, by employing regular ordering of the system connectivity graph, makes it possible to derive an extremely efficient preconditioner from the range space metric (as opposed to the system coefficient matrix). Because of the effectiveness of the preconditioner, the method can achieve performance rates that depend linearly on the number of substructures. The method, termed 'Order N' does not require the assembly of system mass or stiffness matrices, and is therefore amenable to implementation on work stations. Using this method, a 13-substructure model of the Space Station was constructed.

  14. Heterochromatic self-association, a determinant of nuclear organization, does not require sequence homology in Drosophila.

    PubMed Central

    Sage, Brian T; Csink, Amy K

    2003-01-01

    Chromosomes of higher eukaryotes contain blocks of heterochromatin that can associate with each other in the interphase nucleus. A well-studied example of heterochromatic interaction is the brown(Dominant) (bwD) chromosome of D. melanogaster, which contains an approximately 1.6-Mbp insertion of AAGAG repeats near the distal tip of chromosome 2. This insertion causes association of the tip with the centric heterochromatin of chromosome 2 (2h), which contains megabases of AAGAG repeats. Here we describe an example, other than bwD, in which distally translocated heterochromatin associates with centric heterochromatin. Additionally, we show that when a translocation places bwD on a different chromosome, bwD tends to associate with the centric heterochromatin of this chromosome, even when the chromosome contains a small fraction of the sequence homology present elsewhere. To further test the importance of sequence homology in these interactions, we used interspecific mating to introgress the bwD allele from D. melanogaster into D. simulans, which lacks the AAGAG on the autosomes. We find that D. simulans bwD associates with 2h, which lacks the AAGAG sequence, while it does not associate with the AAGAG containing X chromosome heterochromatin. Our results show that intranuclear association of separate heterochromatic blocks does not require that they contain the same sequence. PMID:14668374

  15. Superconductor-insulator transition in a stripe-ordered cuprate

    NASA Astrophysics Data System (ADS)

    Tranquada, John; Homes, C.; Gu, G. D.; Li, Q.; Huecker, M.

    We reconsider the case of La2-xBaxCuO4 with x = 1 / 8 , where spin-stripe order and 2D superconducting correlations develop simultaneously at 40 K. The thermal evolution of the in-plane optical reflectivity suggests the development of a Josephson plasma resonance (JPR) between charge stripes, by analogy with the JPR seen in c-axis reflectivity in the superconducting state of Josephson-coupled CuO2 planes. At low-temperature, when the superconductivity is suppressed by a magnetic field, the resistivity exhibits insulating character. We interpret this as suppression of the Josephson coupling between pair correlations in neighboring charge stripes, with single-particle transport suppressed by the surviving spin-stripe order. To obtain direct evidence that the high-field insulator involves hole pairs localized to 1D stripes will require further experiments. Work at BNL supported by Office of Basic Energy Sciences, US DOE, under Contract No. DE-SC0012704.

  16. What Math Knowledge Does Teaching Require?

    ERIC Educational Resources Information Center

    Thames, Mark Hoover; Ball, Deborah Loewenberg

    2010-01-01

    No one would argue with the claim that teaching mathematics requires mathematics knowledge. However, a clear description of such knowledge needed for teaching has been surprisingly elusive. To differentiate teachers' levels of mathematical knowledge, numerous studies have examined whether a teacher has a certification in math or a degree as well…

  17. Does adding low doses of oral naltrexone to morphine alter the subsequent opioid requirements and side effects in trauma patients?

    PubMed

    Farahmand, Shervin; Ahmadi, Omid; Dehpour, Ahmadreza; Khashayar, Patricia

    2012-01-01

    The present study aims to assess the influence of ultra-low doses of opioid antagonists on the analgesic properties of opioids and their side effects. In the present randomized, double-blind controlled trial, the influence of the combination of ultra-low-dose naltrexone and morphine on the total opioid requirement and the frequency of the subsequent side effects was compared with that of morphine alone (added with placebo) in patients with trauma in the upper or lower extremities. Although the morphine and naltrexone group required 0.04 mg more opioids during the study period, there was no significant difference between the opioid requirements of the 2 groups. Nausea was less frequently reported in patients receiving morphine and naltrexone. The combination of ultra-low-dose naltrexone and morphine in extremity trauma does not affect the opioid requirements; it, however, lowers the risk of nausea. Copyright © 2012 Elsevier Inc. All rights reserved.

  18. Pre-ordering of interfacial water in the pathway of heterogeneous ice nucleation does not lead to a two-step crystallization mechanism.

    PubMed

    Lupi, Laura; Peters, Baron; Molinero, Valeria

    2016-12-07

    According to Classical Nucleation Theory (CNT), the transition from liquid to crystal occurs in a single activated step with a transition state controlled by the size of the crystal embryo. This picture has been challenged in the last two decades by several reports of two-step crystallization processes in which the liquid first produces pre-ordered or dense domains, within which the crystal nucleates in a second step. Pre-ordering preceding crystal nucleation has been recently reported in simulations of ice crystallization, raising the question of whether the mechanism of ice nucleation involves two steps. In this paper, we investigate the heterogeneous nucleation of ice on carbon surfaces. We use molecular simulations with efficient coarse-grained models combined with rare event sampling methods and free energy calculations to elucidate the role of pre-ordering of liquid water at the carbon surface in the reaction coordinate for heterogeneous nucleation. We find that ice nucleation proceeds through a classical mechanism, with a single barrier between liquid and crystal. The reaction coordinate that determines the crossing of the nucleation barrier is the size of the crystal nucleus, as predicted by CNT. Wetting of the critical ice nuclei within pre-ordered domains decreases the nucleation barrier, increasing the nucleation rates. The preferential pathway for crystallization involves the early creation of pre-ordered domains that are the birthplace of the ice crystallites but do not represent a minimum in the free energy pathway from liquid to ice. We conclude that a preferential pathway through an intermediate-order precursor does not necessarily result in a two-step mechanism.

  19. An in fiber experimental approach to photonic quantum digital signatures that does not require quantum memory

    NASA Astrophysics Data System (ADS)

    Collins, Robert J.; Donaldon, Ross J.; Dunjko, Vedran; Wallden, Petros; Clarke, Patrick J.; Andersson, Erika; Jeffers, John; Buller, Gerald S.

    2014-10-01

    Classical digital signatures are commonly used in e-mail, electronic financial transactions and other forms of electronic communications to ensure that messages have not been tampered with in transit, and that messages are transferrable. The security of commonly used classical digital signature schemes relies on the computational difficulty of inverting certain mathematical functions. However, at present, there are no such one-way functions which have been proven to be hard to invert. With enough computational resources certain implementations of classical public key cryptosystems can be, and have been, broken with current technology. It is nevertheless possible to construct information-theoretically secure signature schemes, including quantum digital signature schemes. Quantum signature schemes can be made information theoretically secure based on the laws of quantum mechanics, while classical comparable protocols require additional resources such as secret communication and a trusted authority. Early demonstrations of quantum digital signatures required quantum memory, rendering them impractical at present. Our present implementation is based on a protocol that does not require quantum memory. It also uses the new technique of unambiguous quantum state elimination, Here we report experimental results for a test-bed system, recorded with a variety of different operating parameters, along with a discussion of aspects of the system security.

  20. 41 CFR 102-3.185 - What does this subpart require agencies to do?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... National Academy of Sciences or the National Academy of Public Administration? § 102-3.185 What does this... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false What does this subpart... recommendation provided to an agency by the National Academy of Sciences (NAS) or the National Academy of Public...

  1. 41 CFR 102-3.185 - What does this subpart require agencies to do?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... National Academy of Sciences or the National Academy of Public Administration? § 102-3.185 What does this... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false What does this subpart... recommendation provided to an agency by the National Academy of Sciences (NAS) or the National Academy of Public...

  2. 41 CFR 102-3.185 - What does this subpart require agencies to do?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... National Academy of Sciences or the National Academy of Public Administration? § 102-3.185 What does this... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false What does this subpart... recommendation provided to an agency by the National Academy of Sciences (NAS) or the National Academy of Public...

  3. 41 CFR 102-3.185 - What does this subpart require agencies to do?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... National Academy of Sciences or the National Academy of Public Administration? § 102-3.185 What does this... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false What does this subpart... recommendation provided to an agency by the National Academy of Sciences (NAS) or the National Academy of Public...

  4. 42 CFR 137.298 - Are Self-Governance Tribes required to comply with Executive Orders to fulfill their...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Are Self-Governance Tribes required to comply with Executive Orders to fulfill their environmental responsibilities under section 509 of the Act [25 U.S.C... SERVICES INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction...

  5. 42 CFR 137.298 - Are Self-Governance Tribes required to comply with Executive Orders to fulfill their...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Are Self-Governance Tribes required to comply with Executive Orders to fulfill their environmental responsibilities under section 509 of the Act [25 U.S.C... SERVICES INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction...

  6. 42 CFR 2.61 - Legal effect of order.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Legal effect of order. 2.61 Section 2.61 Public... OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Court Orders Authorizing Disclosure and Use § 2.61 Legal.... Such an order does not compel disclosure. A subpoena or a similar legal mandate must be issued in order...

  7. 42 CFR 2.61 - Legal effect of order.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Legal effect of order. 2.61 Section 2.61 Public... OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Court Orders Authorizing Disclosure and Use § 2.61 Legal.... Such an order does not compel disclosure. A subpoena or a similar legal mandate must be issued in order...

  8. 78 FR 78589 - Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-26

    ...To deliver on the promise of a 21st-Century government that is more efficient, effective and transparent, the Office of Management and Budget (OMB) is streamlining the Federal government's guidance on Administrative Requirements, Cost Principles, and Audit Requirements for Federal awards. These modifications are a key component of a larger Federal effort to more effectively focus Federal resources on improving performance and outcomes while ensuring the financial integrity of taxpayer dollars in partnership with non-Federal stakeholders. This guidance provides a governmentwide framework for grants management which will be complemented by additional efforts to strengthen program outcomes through innovative and effective use of grant-making models, performance metrics, and evaluation. This reform of OMB guidance will reduce administrative burden for non-Federal entities receiving Federal awards while reducing the risk of waste, fraud and abuse. This final guidance supersedes and streamlines requirements from OMB Circulars A-21, A-87, A-110, and A-122 (which have been placed in OMB guidances); Circulars A-89, A-102, and A-133; and the guidance in Circular A-50 on Single Audit Act follow-up. Future reform efforts may eventually seek to incorporate the Cost Principles for Hospitals in Department of Health and Human Services regulations. Copies of the OMB Circulars that are superseded by this guidance are available on OMB's Web site at http://www.whitehouse.gov/omb/circulars--default/. The final guidance consolidates the guidance previously contained in the aforementioned citations into a streamlined format that aims to improve both the clarity and accessibility. This final guidance is located in Title 2 of the Code of Federal Regulations. This final guidance does not broaden the scope of applicability from existing government-wide requirements, affecting Federal awards to non-Federal entities including state and local governments, Indian tribes, institutions of

  9. 20 CFR 1002.33 - Does the employee have to prove that the employer discriminated against him or her in order to be...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... employer discriminated against him or her in order to be eligible for reemployment? 1002.33 Section 1002.33... have to prove that the employer discriminated against him or her in order to be eligible for reemployment? No. The employee is not required to prove that the employer discriminated against him or her...

  10. 10 CFR 605.14 - Limitation of DOE liability.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... PROGRAM § 605.14 Limitation of DOE liability. Awards under this part are subject to the requirement that the maximum DOE obligation to the recipient is the amount shown in the Notice of Financial Assistance Award as the amount of DOE funds obligated. DOE shall not be obligated to make any additional...

  11. 10 CFR 605.14 - Limitation of DOE liability.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... PROGRAM § 605.14 Limitation of DOE liability. Awards under this part are subject to the requirement that the maximum DOE obligation to the recipient is the amount shown in the Notice of Financial Assistance Award as the amount of DOE funds obligated. DOE shall not be obligated to make any additional...

  12. 10 CFR 605.14 - Limitation of DOE liability.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... PROGRAM § 605.14 Limitation of DOE liability. Awards under this part are subject to the requirement that the maximum DOE obligation to the recipient is the amount shown in the Notice of Financial Assistance Award as the amount of DOE funds obligated. DOE shall not be obligated to make any additional...

  13. 10 CFR 605.14 - Limitation of DOE liability.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... PROGRAM § 605.14 Limitation of DOE liability. Awards under this part are subject to the requirement that the maximum DOE obligation to the recipient is the amount shown in the Notice of Financial Assistance Award as the amount of DOE funds obligated. DOE shall not be obligated to make any additional...

  14. 10 CFR 605.14 - Limitation of DOE liability.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... PROGRAM § 605.14 Limitation of DOE liability. Awards under this part are subject to the requirement that the maximum DOE obligation to the recipient is the amount shown in the Notice of Financial Assistance Award as the amount of DOE funds obligated. DOE shall not be obligated to make any additional...

  15. corona Is Required for Higher-Order Assembly of Transverse Filaments into Full-Length Synaptonemal Complex in Drosophila Oocytes

    PubMed Central

    Page, Scott L.; Khetani, Radhika S.; Lake, Cathleen M.; Nielsen, Rachel J.; Jeffress, Jennifer K.; Warren, William D.; Bickel, Sharon E.; Hawley, R. Scott

    2008-01-01

    The synaptonemal complex (SC) is an intricate structure that forms between homologous chromosomes early during the meiotic prophase, where it mediates homolog pairing interactions and promotes the formation of genetic exchanges. In Drosophila melanogaster, C(3)G protein forms the transverse filaments (TFs) of the SC. The N termini of C(3)G homodimers localize to the Central Element (CE) of the SC, while the C-termini of C(3)G connect the TFs to the chromosomes via associations with the axial elements/lateral elements (AEs/LEs) of the SC. Here, we show that the Drosophila protein Corona (CONA) co-localizes with C(3)G in a mutually dependent fashion and is required for the polymerization of C(3)G into mature thread-like structures, in the context both of paired homologous chromosomes and of C(3)G polycomplexes that lack AEs/LEs. Although AEs assemble in cona oocytes, they exhibit defects that are characteristic of c(3)G mutant oocytes, including failure of AE alignment and synapsis. These results demonstrate that CONA, which does not contain a coiled coil domain, is required for the stable ‘zippering’ of TFs to form the central region of the Drosophila SC. We speculate that CONA's role in SC formation may be similar to that of the mammalian CE proteins SYCE2 and TEX12. However, the observation that AE alignment and pairing occurs in Tex12 and Syce2 mutant meiocytes but not in cona oocytes suggests that the SC plays a more critical role in the stable association of homologs in Drosophila than it does in mammalian cells. PMID:18802461

  16. Reduction in chemotherapy order errors with computerized physician order entry.

    PubMed

    Meisenberg, Barry R; Wright, Robert R; Brady-Copertino, Catherine J

    2014-01-01

    To measure the number and type of errors associated with chemotherapy order composition associated with three sequential methods of ordering: handwritten orders, preprinted orders, and computerized physician order entry (CPOE) embedded in the electronic health record. From 2008 to 2012, a sample of completed chemotherapy orders were reviewed by a pharmacist for the number and type of errors as part of routine performance improvement monitoring. Error frequencies for each of the three distinct methods of composing chemotherapy orders were compared using statistical methods. The rate of problematic order sets-those requiring significant rework for clarification-was reduced from 30.6% with handwritten orders to 12.6% with preprinted orders (preprinted v handwritten, P < .001) to 2.2% with CPOE (preprinted v CPOE, P < .001). The incidence of errors capable of causing harm was reduced from 4.2% with handwritten orders to 1.5% with preprinted orders (preprinted v handwritten, P < .001) to 0.1% with CPOE (CPOE v preprinted, P < .001). The number of problem- and error-containing chemotherapy orders was reduced sequentially by preprinted order sets and then by CPOE. CPOE is associated with low error rates, but it did not eliminate all errors, and the technology can introduce novel types of errors not seen with traditional handwritten or preprinted orders. Vigilance even with CPOE is still required to avoid patient harm.

  17. 2 CFR 902.225 - Whom in the DOE does a recipient other than an individual notify about a criminal drug conviction?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Whom in the DOE does a recipient other than...-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Other Than Individuals § 902.225 Whom in the DOE does a recipient other than an individual notify about a criminal drug conviction? A...

  18. 2 CFR 902.225 - Whom in the DOE does a recipient other than an individual notify about a criminal drug conviction?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Whom in the DOE does a recipient other than...-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Other Than Individuals § 902.225 Whom in the DOE does a recipient other than an individual notify about a criminal drug conviction? A...

  19. 2 CFR 902.225 - Whom in the DOE does a recipient other than an individual notify about a criminal drug conviction?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Whom in the DOE does a recipient other than...-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Other Than Individuals § 902.225 Whom in the DOE does a recipient other than an individual notify about a criminal drug conviction? A...

  20. 2 CFR 902.225 - Whom in the DOE does a recipient other than an individual notify about a criminal drug conviction?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Whom in the DOE does a recipient other than...-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Other Than Individuals § 902.225 Whom in the DOE does a recipient other than an individual notify about a criminal drug conviction? A...

  1. 10 CFR 602.13 - Limitation of DOE liability.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ASSISTANCE PROGRAM § 602.13 Limitation of DOE liability. Awards made under this part are subject to the requirement that the maximum DOE obligation to the recipient is the amount shown in the Notice of Financial Assistance Award as the amount of DOE funds obligated. DOE shall not be obligated to make any additional...

  2. 10 CFR 602.13 - Limitation of DOE liability.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ASSISTANCE PROGRAM § 602.13 Limitation of DOE liability. Awards made under this part are subject to the requirement that the maximum DOE obligation to the recipient is the amount shown in the Notice of Financial Assistance Award as the amount of DOE funds obligated. DOE shall not be obligated to make any additional...

  3. 10 CFR 602.13 - Limitation of DOE liability.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ASSISTANCE PROGRAM § 602.13 Limitation of DOE liability. Awards made under this part are subject to the requirement that the maximum DOE obligation to the recipient is the amount shown in the Notice of Financial Assistance Award as the amount of DOE funds obligated. DOE shall not be obligated to make any additional...

  4. 10 CFR 602.13 - Limitation of DOE liability.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ASSISTANCE PROGRAM § 602.13 Limitation of DOE liability. Awards made under this part are subject to the requirement that the maximum DOE obligation to the recipient is the amount shown in the Notice of Financial Assistance Award as the amount of DOE funds obligated. DOE shall not be obligated to make any additional...

  5. 10 CFR 602.13 - Limitation of DOE liability.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ASSISTANCE PROGRAM § 602.13 Limitation of DOE liability. Awards made under this part are subject to the requirement that the maximum DOE obligation to the recipient is the amount shown in the Notice of Financial Assistance Award as the amount of DOE funds obligated. DOE shall not be obligated to make any additional...

  6. Recording from two neurons: second-order stimulus reconstruction from spike trains and population coding.

    PubMed

    Fernandes, N M; Pinto, B D L; Almeida, L O B; Slaets, J F W; Köberle, R

    2010-10-01

    We study the reconstruction of visual stimuli from spike trains, representing the reconstructed stimulus by a Volterra series up to second order. We illustrate this procedure in a prominent example of spiking neurons, recording simultaneously from the two H1 neurons located in the lobula plate of the fly Chrysomya megacephala. The fly views two types of stimuli, corresponding to rotational and translational displacements. Second-order reconstructions require the manipulation of potentially very large matrices, which obstructs the use of this approach when there are many neurons. We avoid the computation and inversion of these matrices using a convenient set of basis functions to expand our variables in. This requires approximating the spike train four-point functions by combinations of two-point functions similar to relations, which would be true for gaussian stochastic processes. In our test case, this approximation does not reduce the quality of the reconstruction. The overall contribution to stimulus reconstruction of the second-order kernels, measured by the mean squared error, is only about 5% of the first-order contribution. Yet at specific stimulus-dependent instants, the addition of second-order kernels represents up to 100% improvement, but only for rotational stimuli. We present a perturbative scheme to facilitate the application of our method to weakly correlated neurons.

  7. Effects of Ordering Strategies and Programming Paradigms on Sparse Matrix Computations

    NASA Technical Reports Server (NTRS)

    Oliker, Leonid; Li, Xiaoye; Husbands, Parry; Biswas, Rupak; Biegel, Bryan (Technical Monitor)

    2002-01-01

    The Conjugate Gradient (CG) algorithm is perhaps the best-known iterative technique to solve sparse linear systems that are symmetric and positive definite. For systems that are ill-conditioned, it is often necessary to use a preconditioning technique. In this paper, we investigate the effects of various ordering and partitioning strategies on the performance of parallel CG and ILU(O) preconditioned CG (PCG) using different programming paradigms and architectures. Results show that for this class of applications: ordering significantly improves overall performance on both distributed and distributed shared-memory systems, that cache reuse may be more important than reducing communication, that it is possible to achieve message-passing performance using shared-memory constructs through careful data ordering and distribution, and that a hybrid MPI+OpenMP paradigm increases programming complexity with little performance gains. A implementation of CG on the Cray MTA does not require special ordering or partitioning to obtain high efficiency and scalability, giving it a distinct advantage for adaptive applications; however, it shows limited scalability for PCG due to a lack of thread level parallelism.

  8. 48 CFR 941.201-70 - DOE Directives.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... of Energy (DOE) Order 430.2B, Departmental Energy, Renewable Energy and Transportation Management, or... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false DOE Directives. 941.201-70 Section 941.201-70 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SPECIAL CATEGORIES OF...

  9. 10 CFR 820.11 - Information requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Information requirements. 820.11 Section 820.11 Energy DEPARTMENT OF ENERGY PROCEDURAL RULES FOR DOE NUCLEAR ACTIVITIES General § 820.11 Information requirements. (a) Any information pertaining to a nuclear activity provided to DOE by any person or maintained by...

  10. 20 CFR 664.320 - Does the requirement that at least 30 percent of youth funds be used to provide activities to out...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of youth funds be used to provide activities to out-of-school youth apply to all youth funds? 664.320... ACTIVITIES UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Out-of-School Youth § 664.320 Does the requirement that at least 30 percent of youth funds be used to provide activities to out-of-school youth apply to...

  11. 20 CFR 641.650 - Does the requirement that not less than 75 percent of the funds be used to pay participant wages...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Does the requirement that not less than 75 percent of the funds be used to pay participant wages and fringe benefits apply to section 502(e) activities? 641.650 Section 641.650 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING THE SENIOR...

  12. TYLCV-Is movement in planta does not require V2 protein

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hak, Hagit; Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem; Levy, Yael

    Tomato yellow leaf curl virus (TYLCV), a major tomato pathogen causing extensive crop losses, is a whitefly-transmitted geminivirus. V2 mutants of TYLCV-Is and related viruses tend to induce symptomless infection with attenuated viral DNA levels, while accumulating close to wild-type DNA levels in protoplasts, suggesting V2 as a movement protein. The discovery of plant-silencing mechanisms and viral silencing suppressors, V2 included, led us to reconsider V2's involvement in viral movement. We studied two mutant versions of the virus, one impaired in V2 silencing-suppression activity, and another carrying a non-translatable V2. While both mutant viruses spread in the infected plant tomore » newly emerged leaves at the same rate as the wild-type virus, their DNA-accumulation levels were tenfold lower than in the wild-type virus. Thus, we suggest that the setback in virus proliferation, previously ascribed to a movement impediment, is due to lack of silencing-suppression activity. - Highlights: • TYLCV-Is V2 protein is localized in distinct microbodies throughout the cell cytoplasm, around the nucleus and in association with cytoplasmic strands but is not associated with the plasmodesmata. • Disruption of RNA-silencing suppression activity of TYLCV-Is V2 protein causes low titer of the virus in the infected plants. • The movement of TYLCV-Is in planta does not require a functional V2 protein.« less

  13. 2 CFR 902.300 - Whom in the DOE does a recipient who is an individual notify about a criminal drug conviction?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Whom in the DOE does a recipient who is an... WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Who Are Individuals § 902.300 Whom in the DOE does a recipient who is an individual notify about a criminal drug conviction? A recipient who is an...

  14. 2 CFR 902.300 - Whom in the DOE does a recipient who is an individual notify about a criminal drug conviction?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Whom in the DOE does a recipient who is an... WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Who Are Individuals § 902.300 Whom in the DOE does a recipient who is an individual notify about a criminal drug conviction? A recipient who is an...

  15. 2 CFR 902.300 - Whom in the DOE does a recipient who is an individual notify about a criminal drug conviction?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Whom in the DOE does a recipient who is an... WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Who Are Individuals § 902.300 Whom in the DOE does a recipient who is an individual notify about a criminal drug conviction? A recipient who is an...

  16. 2 CFR 902.300 - Whom in the DOE does a recipient who is an individual notify about a criminal drug conviction?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Whom in the DOE does a recipient who is an... WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Who Are Individuals § 902.300 Whom in the DOE does a recipient who is an individual notify about a criminal drug conviction? A recipient who is an...

  17. 10 CFR 205.10 - Effective date of orders.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Effective date of orders. 205.10 Section 205.10 Energy DEPARTMENT OF ENERGY OIL ADMINISTRATIVE PROCEDURES AND SANCTIONS General Provisions § 205.10 Effective date of orders. Any order issued by the DOE or a State Office under this chapter is effective as against...

  18. Waste information management system: a web-based system for DOE waste forecasting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Geisler, T.J.; Shoffner, P.A.; Upadhyay, U.

    2007-07-01

    The implementation of the Department of Energy (DOE) mandated accelerated cleanup program has created significant potential technical impediments that must be overcome. The schedule compression will require close coordination and a comprehensive review and prioritization of the barriers that may impede treatment and disposition of the waste streams at each site. Many issues related to site waste treatment and disposal have now become potential critical path issues under the accelerated schedules. In order to facilitate accelerated cleanup initiatives, waste managers at DOE field sites and at DOE headquarters in Washington, D.C., need timely waste forecast information regarding the volumes andmore » types of waste that will be generated by DOE sites over the next 25 years. Each local DOE site has historically collected, organized, and displayed site waste forecast information in separate and unique systems. However, waste information from all sites needs a common application to allow interested parties to understand and view the complete complex-wide picture. A common application would allow identification of total waste volumes, material classes, disposition sites, choke points, and technological or regulatory barriers to treatment and disposal. The Applied Research Center (ARC) at Florida International University (FIU) in Miami, Florida, has completed the development of this web-based forecast system. (authors)« less

  19. DOE 2011 occupational radiation exposure

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    none,

    2012-12-01

    The U.S. Department of Energy (DOE) Office of Analysis within the Office of Health, Safety and Security (HSS) publishes the annual DOE Occupational Radiation Exposure Report to provide an overview of the status of radiation protection practices at DOE (including the National Nuclear Security Administration [NNSA]). The DOE 2011 Occupational Radiation Exposure Report provides an evaluation of DOE-wide performance regarding compliance with Title 10, Code of Federal Regulations (C.F.R.), Part 835, Occupational Radiation Protection dose limits and as low as reasonably achievable (ALARA) process requirements. In addition, the report provides data to DOE organizations responsible for developing policies for protectionmore » of individuals from the adverse health effects of radiation. The report provides a summary and an analysis of occupational radiation exposure information from the monitoring of individuals involved in DOE activities. The occupational radiation exposure information is analyzed in terms of aggregate data, dose to individuals, and dose by site over the past five years.« less

  20. DOE technical standards list: Directory of DOE and contractor personnel involved in non-government standards activities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1996-08-01

    The body of this document contains a listing of DOE employees and DOE contractors who have submitted form DOE F 1300.2, Record of Non-Government Standards Activity, which is attached to the end of this document and to DOE Order 1300.2A. Additional names were added from rosters supplied by non-Government standards bodies. The committees or governing bodies in which the person participates is listed after each name. An asterisk preceding the committee notation indicates that the person has identified himself or herself as the DOE representative on that committee. Appendices to this document are also provided to sort the information bymore » the parent employment organization, by non-Government standards activity, and by the proper names of the non-Government standards organizations and committees. DOE employees and contractors listed in this TSL are those recorded as of July 1, 1996.« less

  1. Time-to-contact estimation of accelerated stimuli is based on first-order information.

    PubMed

    Benguigui, Nicolas; Ripoll, Hubert; Broderick, Michael P

    2003-12-01

    The goal of this study was to test whether 1st-order information, which does not account for acceleration, is used (a) to estimate the time to contact (TTC) of an accelerated stimulus after the occlusion of a final part of its trajectory and (b) to indirectly intercept an accelerated stimulus with a thrown projectile. Both tasks require the production of an action on the basis of predictive information acquired before the arrival of the stimulus at the target and allow the experimenter to make quantitative predictions about the participants' use (or nonuse) of 1st-order information. The results show that participants do not use information about acceleration and that they commit errors that rely quantitatively on 1st-order information even when acceleration is psychophysically detectable. In the indirect interceptive task, action is planned about 200 ms before the initiation of the movement, at which time the 1st-order TTC attains a critical value. ((c) 2003 APA, all rights reserved)

  2. Ordering Transformations in High-Entropy Alloys

    NASA Astrophysics Data System (ADS)

    Singh, Prashant; Johnson, Duane D.

    The high-temperature disordered phase of multi-component alloys, including high-entropy alloys (HEA), generally must experience segregation or else passes through partially-ordered phases to reach the low-temperature, fully-ordered phase. Our first-principles KKR-CPA-based atomic short-range ordering (SRO) calculations (analyzed as concentration-waves) reveal the competing partially and fully ordered phases in HEA, and these phases can be then directly assessed from KKR-CPA results in larger unit cells [Phys. Rev. B 91, 224204 (2015)]. For AlxCrFeNiTi0.25, Liu et al. [J Alloys Compd 619, 610 (2015)] experimentally find FCC+BCC coexistence that changes to BCC with increasing Al (x from 0-to-1), which then exhibits a partially-ordered B2 at low temperatures. CALPHAD (Calculation of Phase Diagrams) predicts a region with L21+B2 coexistence. From KKR-CPA calculations, we find crossover versus Al from FCC+BCC coexistence to BCC, as observed, and regions for partially-order B2+L21 coexistence, as suggest by CALPHAD. Our combined first-principles KKR-CPA method provides a powerful approach in predicting SRO and completing long-range order in HEA and other complex alloys. Supported by the U.S. DOE, Office of Science, Basic Energy Sciences, Materials Science and Engineering Division. Work was performed at Ames Laboratory, which is operated by Iowa State University for the U.S. DOE under Contract #DE-AC02-07CH11358.

  3. Reflex test reminders in required cancer synoptic templates decrease order entry error: An analysis of mismatch repair immunohistochemical orders to screen for Lynch syndrome.

    PubMed

    Kilgore, Mark R; McIlwain, Carrie A; Schmidt, Rodney A; Norquist, Barbara M; Swisher, Elizabeth M; Garcia, Rochelle L; Rendi, Mara H

    2016-01-01

    Endometrial carcinoma (EC) is the most common extracolonic malignant neoplasm associated with Lynch syndrome (LS). LS is caused by autosomal dominant germline mutations in DNA mismatch repair (MMR) genes. Screening for LS in EC is often evaluated by loss of immunohistochemical (IHC) expression of DNA MMR enzymes MLH1, MSH2, MSH6, and PMS2 (MMR IHC). In July 2013, our clinicians asked that we screen all EC in patients ≤60 for loss of MMR IHC expression. Despite this policy, several cases were not screened or screening was delayed. We implemented an informatics-based approach to ensure that all women who met criteria would have timely screening. Reports are created in PowerPath (Sunquest Information Systems, Tucson, AZ) with custom synoptic templates. We implemented an algorithm on March 6, 2014 requiring pathologists to address MMR IHC in patients ≤60 with EC before sign out (S/O). Pathologists must answer these questions: is patient ≤60 (yes/no), if yes, follow-up questions (IHC done previously, ordered with addendum to follow, results included in report, N/A, or not ordered), if not ordered, one must explain. We analyzed cases from July 18, 2013 to August 31, 2016 preimplementation (PreImp) and postimplementation (PostImp) that met criteria. Data analysis was performed using the standard data package included with GraphPad Prism ® 7.00 (GraphPad Software, Inc., La Jolla, CA, USA). There were 147 patients who met criteria (29 PreImp and 118 PostImp). IHC was ordered in a more complete and timely fashion PostImp than PreImp. PreImp, 4/29 (13.8%) cases did not get any IHC, but PostImp, only 4/118 (3.39%) were missed ( P = 0.0448). Of cases with IHC ordered, 60.0% (15/25) were ordered before or at S/O PreImp versus 91.2% (104/114) PostImp ( P = 0.0004). Relative to day of S/O, the mean days of order delay were longer and more variable PreImp versus PostImp (12.9 ± 40.7 vs. -0.660 ± 1.15; P = 0.0227), with the average being before S/O PostImp. This algorithm

  4. Software compensation of eddy current fields in multislice high order dynamic shimming.

    PubMed

    Sengupta, Saikat; Avison, Malcolm J; Gore, John C; Brian Welch, E

    2011-06-01

    Dynamic B(0) shimming (DS) can produce better field homogeneity than static global shimming by dynamically updating slicewise shim values in a multislice acquisition. The performance of DS however is limited by eddy current fields produced by the switching of 2nd and 3rd order unshielded shims. In this work, we present a novel method of eddy field compensation (EFC) applied to higher order shim induced eddy current fields in multislice DS. This method does not require shim shielding, extra hardware for eddy current compensation or subject specific prescanning. The interactions between shim harmonics are modeled assuming steady state of the medium and long time constant, cross and self term eddy fields in a DS experiment and 'correction factors' characterizing the entire set of shim interactions are derived. The correction factors for a given time between shim switches are shown to be invariable with object scanned, shim switching pattern and actual shim values, allowing for their generalized prospective use. Phantom and human head, 2nd and 3rd order DS experiments performed without any hardware eddy current compensation using the technique show large reductions in field gradients and offsets leading to significant improvements in image quality. This method holds promise as an alternative to expensive hardware based eddy current compensation required in 2nd and 3rd order DS. Copyright © 2011 Elsevier Inc. All rights reserved.

  5. Two-Jet Rate in e+e- at Next-to-Next-to-Leading-Logarithmic Order

    NASA Astrophysics Data System (ADS)

    Banfi, Andrea; McAslan, Heather; Monni, Pier Francesco; Zanderighi, Giulia

    2016-10-01

    We present the first next-to-next-to-leading-logarithmic resummation for the two-jet rate in e+e- annihilation in the Durham and Cambridge algorithms. The results are obtained by extending the ares method to observables involving any global, recursively infrared and collinear safe jet algorithm in e+e- collisions. As opposed to other methods, this approach does not require a factorization theorem for the observables. We present predictions matched to next-to-next-to-leading order and a comparison to LEP data.

  6. 10 CFR 490.606 - Proposed assessments and orders.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 3 2013-01-01 2013-01-01 false Proposed assessments and orders. 490.606 Section 490.606 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Investigations and Enforcement § 490.606 Proposed assessments and orders. DOE may issue a proposed assessment of, and...

  7. 10 CFR 490.606 - Proposed assessments and orders.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Proposed assessments and orders. 490.606 Section 490.606 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Investigations and Enforcement § 490.606 Proposed assessments and orders. DOE may issue a proposed assessment of, and...

  8. 10 CFR 490.606 - Proposed assessments and orders.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Proposed assessments and orders. 490.606 Section 490.606 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Investigations and Enforcement § 490.606 Proposed assessments and orders. DOE may issue a proposed assessment of, and...

  9. 10 CFR 490.606 - Proposed assessments and orders.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 3 2014-01-01 2014-01-01 false Proposed assessments and orders. 490.606 Section 490.606 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Investigations and Enforcement § 490.606 Proposed assessments and orders. DOE may issue a proposed assessment of, and...

  10. 10 CFR 490.606 - Proposed assessments and orders.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 3 2012-01-01 2012-01-01 false Proposed assessments and orders. 490.606 Section 490.606 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Investigations and Enforcement § 490.606 Proposed assessments and orders. DOE may issue a proposed assessment of, and...

  11. Public key infrastructure for DOE security research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aiken, R.; Foster, I.; Johnston, W.E.

    This document summarizes the Department of Energy`s Second Joint Energy Research/Defence Programs Security Research Workshop. The workshop, built on the results of the first Joint Workshop which reviewed security requirements represented in a range of mission-critical ER and DP applications, discussed commonalties and differences in ER/DP requirements and approaches, and identified an integrated common set of security research priorities. One significant conclusion of the first workshop was that progress in a broad spectrum of DOE-relevant security problems and applications could best be addressed through public-key cryptography based systems, and therefore depended upon the existence of a robust, broadly deployed public-keymore » infrastructure. Hence, public-key infrastructure ({open_quotes}PKI{close_quotes}) was adopted as a primary focus for the second workshop. The Second Joint Workshop covered a range of DOE security research and deployment efforts, as well as summaries of the state of the art in various areas relating to public-key technologies. Key findings were that a broad range of DOE applications can benefit from security architectures and technologies built on a robust, flexible, widely deployed public-key infrastructure; that there exists a collection of specific requirements for missing or undeveloped PKI functionality, together with a preliminary assessment of how these requirements can be met; that, while commercial developments can be expected to provide many relevant security technologies, there are important capabilities that commercial developments will not address, due to the unique scale, performance, diversity, distributed nature, and sensitivity of DOE applications; that DOE should encourage and support research activities intended to increase understanding of security technology requirements, and to develop critical components not forthcoming from other sources in a timely manner.« less

  12. Connectivity strategies for higher-order neural networks applied to pattern recognition

    NASA Technical Reports Server (NTRS)

    Spirkovska, Lilly; Reid, Max B.

    1990-01-01

    Different strategies for non-fully connected HONNs (higher-order neural networks) are discussed, showing that by using such strategies an input field of 128 x 128 pixels can be attained while still achieving in-plane rotation and translation-invariant recognition. These techniques allow HONNs to be used with the larger input scenes required for practical pattern-recognition applications. The number of interconnections that must be stored has been reduced by a factor of approximately 200,000 in a T/C case and about 2000 in a Space Shuttle/F-18 case by using regional connectivity. Third-order networks have been simulated using several connection strategies. The method found to work best is regional connectivity. The main advantages of this strategy are the following: (1) it considers features of various scales within the image and thus gets a better sample of what the image looks like; (2) it is invariant to shape-preserving geometric transformations, such as translation and rotation; (3) the connections are predetermined so that no extra computations are necessary during run time; and (4) it does not require any extra storage for recording which connections were formed.

  13. 49 CFR 40.160 - What does the MRO do when a valid test result cannot be produced and a negative result is required?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false What does the MRO do when a valid test result cannot be produced and a negative result is required? 40.160 Section 40.160 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Medical Review Officers and the Verification...

  14. Civilian Radioactive Waste Management System Requirements Document

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    C.A. Kouts

    2006-05-10

    The CRD addresses the requirements of Department of Energy (DOE) Order 413.3-Change 1, ''Program and Project Management for the Acquisition of Capital Assets'', by providing the Secretarial Acquisition Executive (Level 0) scope baseline and the Program-level (Level 1) technical baseline. The Secretarial Acquisition Executive approves the Office of Civilian Radioactive Waste Management's (OCRWM) critical decisions and changes against the Level 0 baseline; and in turn, the OCRWM Director approves all changes against the Level 1 baseline. This baseline establishes the top-level technical scope of the CRMWS and its three system elements, as described in section 1.3.2. The organizations responsible formore » design, development, and operation of system elements described in this document must therefore prepare subordinate project-level documents that are consistent with the CRD. Changes to requirements will be managed in accordance with established change and configuration control procedures. The CRD establishes requirements for the design, development, and operation of the CRWMS. It specifically addresses the top-level governing laws and regulations (e.g., ''Nuclear Waste Policy Act'' (NWPA), 10 Code of Federal Regulations (CFR) Part 63, 10 CFR Part 71, etc.) along with specific policy, performance requirements, interface requirements, and system architecture. The CRD shall be used as a vehicle to incorporate specific changes in technical scope or performance requirements that may have significant program implications. Such may include changes to the program mission, changes to operational capability, and high visibility stakeholder issues. The CRD uses a systems approach to: (1) identify key functions that the CRWMS must perform, (2) allocate top-level requirements derived from statutory, regulatory, and programmatic sources, and (3) define the basic elements of the system architecture and operational concept. Project-level documents address CRD requirements by

  15. 77 FR 35027 - Serenity Café; Decision and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-12

    ... Cause Order proposed the denial of Serenity Caf[eacute]'s application for a DEA Certificate of...)). Next, the Order alleged that Applicant does not have a valid Illinois Department of Human Services... of Serenity Caf[eacute]. GX 1, at 3; GX 6. Since the date of service of the Order, thirty days have...

  16. Does unbelted safety requirement affect protection for belted occupants?

    PubMed

    Hu, Jingwen; Klinich, Kathleen D; Manary, Miriam A; Flannagan, Carol A C; Narayanaswamy, Prabha; Reed, Matthew P; Andreen, Margaret; Neal, Mark; Lin, Chin-Hsu

    2017-05-29

    Federal regulations in the United States require vehicles to meet occupant performance requirements with unbelted test dummies. Removing the test requirements with unbelted occupants might encourage the deployment of seat belt interlocks and allow restraint optimization to focus on belted occupants. The objective of this study is to compare the performance of restraint systems optimized for belted-only occupants with those optimized for both belted and unbelted occupants using computer simulations and field crash data analyses. In this study, 2 validated finite element (FE) vehicle/occupant models (a midsize sedan and a midsize SUV) were selected. Restraint design optimizations under standardized crash conditions (U.S.-NCAP and FMVSS 208) with and without unbelted requirements were conducted using Hybrid III (HIII) small female and midsize male anthropomorphic test devices (ATDs) in both vehicles on both driver and right front passenger positions. A total of 10 to 12 design parameters were varied in each optimization using a combination of response surface method (RSM) and genetic algorithm. To evaluate the field performance of restraints optimized with and without unbelted requirements, 55 frontal crash conditions covering a greater variety of crash types than those in the standardized crashes were selected. A total of 1,760 FE simulations were conducted for the field performance evaluation. Frontal crashes in the NASS-CDS database from 2002 to 2012 were used to develop injury risk curves and to provide the baseline performance of current restraint system and estimate the injury risk change by removing the unbelted requirement. Unbelted requirements do not affect the optimal seat belt and airbag design parameters in 3 out of 4 vehicle/occupant position conditions, except for the SUV passenger side. Overall, compared to the optimal designs with unbelted requirements, optimal designs without unbelted requirements generated the same or lower total injury risks for

  17. 10 CFR 1040.89-3 - Information requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Information requirements. 1040.89-3 Section 1040.89-3... of Doe Recipients § 1040.89-3 Information requirements. Each recipient shall: (a) Upon request make available to DOE information necessary to determine whether the recipient is complying with the Act and...

  18. Radiation-reaction force on a small charged body to second order

    NASA Astrophysics Data System (ADS)

    Moxon, Jordan; Flanagan, Éanna

    2018-05-01

    In classical electrodynamics, an accelerating charged body emits radiation and experiences a corresponding radiation-reaction force, or self-force. We extend to higher order in the total charge a previous rigorous derivation of the electromagnetic self-force in flat spacetime by Gralla, Harte, and Wald. The method introduced by Gralla, Harte, and Wald computes the self-force from the Maxwell field equations and conservation of stress-energy in a limit where the charge, size, and mass of the body go to zero, and it does not require regularization of a singular self-field. For our higher-order computation, an adjustment of the definition of the mass of the body is necessary to avoid including self-energy from the electromagnetic field sourced by the body in the distant past. We derive the evolution equations for the mass, spin, and center-of-mass position of the body through second order. We derive, for the first time, the second-order acceleration dependence of the evolution of the spin (self-torque), as well as a mixing between the extended body effects and the acceleration-dependent effects on the overall body motion.

  19. Supporting documentation for requested exceptions to standing orders 96-36 (East) and 96-34 (West)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schofield, J.S.

    1997-01-16

    On November 1, 1996 the U.S. Department of Energy (DOE), Richland Operations Office (RL) approved the Flammable Gas Unreviewed Safety Question (USQ) (Wagoner 1996). The Tank Waste Remediation System issued (Hall 1996) two standing orders (96-36 East; and 96-34 West) to implement the requirements and authorization for continued operations included in the RL letter (Wagoner 199E). These standing orders included several requirements for the control of ignition sources (Appendix B, Section 7.0 ``Ignition Source Controls``) that include requirements for the design and operation of ``...equipment and materials used in the conduct of work...`` in Tank Farms. A verbatim compliance reviewmore » of these ignition source controls identified several pieces of equipment and materials which have been used routinely in Tanks Farms for many years in support of safe operation that either could not: meet the equivalent design or safety provisions included in the standing orders (Hall 1996), or 21. be modified in a timely manner to meet safety and programmatic commitments. When the standing order was prepared it was anticipated that there would be a need to approve temporary exceptions. Appendix B, Section 7.0 of the standing order (Hall 1996) reads in part as follows: ``For activities where compliance will require modification to equipment or new materials, any temporary exceptions specifically allowed by RL until full compliance with the standing order is accomplished, are listed in Table 3.`` This document provides a specific listing of the items of equipment or material that could not meet the above two criteria. Also included in a table for each item is the following information: 1. the applicable control in the standing orders that could not be met, 2. under what conditions (when) the control could not be met, 3. a discussion of the applicability of the standing order, 4. a discussion of the risk associated with continued use of the equipment or material, and 5. a discussion

  20. Male sexual behavior does not require elevated testosterone in a lizard (Coleonyx elegans, Eublepharidae).

    PubMed

    Golinski, Alison; John-Alder, Henry; Kratochvíl, Lukáš

    2011-01-01

    Male sexual behavior depends on gonadal androgens in species of all major vertebrate lineages, including reptiles. However, male sexual behavior includes distinct appetitive and consummatory phases, typically denoted as courtship and mounting, with potentially different hormonal control. Different proximate controls of courtship versus mounting could enable disconnected evolutionary losses and gains of various aspects of male sexual behavior. Male courtship display, which is activated by testosterone (T) in many species, is an ancestral trait in the lizard family Eublepharidae. However, Coleonyx elegans (Yucatan Banded Gecko) lost the courtship display, while retaining a highly simplified male sexual behavior that involves only mounting for copulation. We performed surgical manipulations (castration with and without T replacement in adult males; implantation of adult females with exogenous T) to investigate hormonal mechanisms involved in this evolutionary novelty. Our results indicate that the expression of simplified sexual behavior in C. elegans does not require elevated circulating levels of T, a finding that is previously unreported in lizards. In females, however, exogenous T induced male-like mounting. Thus, the mounting phase of sexual behavior is not activated by T in the traditional sense of this term but probably requires post-natal, maturational organization (if not periodic reorganization) by androgens. We conclude that the simplification of male sexual behavior and its independence from elevated levels of circulating androgens in C. elegans evolved via 1) evolutionary loss of the androgen-activated courtship display and 2) retention of the mounting phase, which has a longer "functional memory" for the effects of androgenic steroids. Copyright © 2010 Elsevier Inc. All rights reserved.

  1. 10 CFR 820.41 - Compliance order.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... The Secretary may issue to any person involved in a DOE nuclear activity a Compliance Order that: (a) Identifies a situation that violates, potentially violates, or otherwise is inconsistent with the Act, a...) States the reasons for the remedy or other action. ...

  2. Environmental Performance Report 2013: Annual Site Environmental Report per the U.S. Department of Energy Order 231.1-1B (Management Publication)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schlomberg, K.; Eickhoff, J.; Beatty, B.

    The National Renewable Energy Laboratory's (NREL's) Environmental Performance Report provides a description of the laboratory's environmental management activities for 2013, including information on environmental and sustainability performance, environmental compliance activities and status, and environmental protection programs, highlights, and successes. The purpose of this report is to ensure that U.S. Department of Energy (DOE) and the public receive timely, accurate information about events that have affected or could adversely affect the health, safety, and security of the public or workers; the environment; or the operations of DOE facilities. This report meets the requirements of the Annual Site Environmental Report and ismore » prepared in accordance with the DOE Order 231.1B, Environment, Safety and Health Reporting.« less

  3. DOE DISS/ET pilot system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Strait, R.S.; Wagner, E.E.

    1994-07-01

    The US Department of Energy (DOE) Office of Safeguards and Security initiated the DOE Integrated Security System / Electronic Transfer (DISS/ET) for the purpose of reducing the time required to process security clearance requests. DISS/ET will be an integrated system using electronic commerce technologies for the collection and processing of personnel security clearance data, and its transfer between DOE local security clearance offices, DOE Operations Offices, and the Office of Personnel Management. The system will use electronic forms to collect clearance applicant data. The forms data will be combined with electronic fingerprint images and packaged in a secure encrypted electronicmore » mail envelope for transmission across the Internet. Information provided by the applicant will be authenticated using digital signatures. All processing will be done electronically.« less

  4. Designing eHealth that Matters via a Multidisciplinary Requirements Development Approach

    PubMed Central

    Wentzel, Jobke; Van Gemert-Pijnen, Julia EWC

    2013-01-01

    user profiles in the form of personas (fictitious end users, representative of a primary end user group). Conclusions The requirements development approach presented in this article enables eHealth developers to apply a systematic and multi-disciplinary approach towards the creation of requirements. The cooperation between health, engineering, and social sciences creates a situation in which a mismatch between design, end users, and the organizational context can be avoided. Furthermore, we suggest to evaluate eHealth on a feature-specific level in order to learn exactly why such a technology does or does not live up to its expectations. PMID:23796508

  5. Designing eHealth that Matters via a Multidisciplinary Requirements Development Approach.

    PubMed

    Van Velsen, Lex; Wentzel, Jobke; Van Gemert-Pijnen, Julia Ewc

    2013-06-24

    personas (fictitious end users, representative of a primary end user group). The requirements development approach presented in this article enables eHealth developers to apply a systematic and multi-disciplinary approach towards the creation of requirements. The cooperation between health, engineering, and social sciences creates a situation in which a mismatch between design, end users, and the organizational context can be avoided. Furthermore, we suggest to evaluate eHealth on a feature-specific level in order to learn exactly why such a technology does or does not live up to its expectations.

  6. High order field-to-field corrections for imaging and overlay to achieve sub 20-nm lithography requirements

    NASA Astrophysics Data System (ADS)

    Mulkens, Jan; Kubis, Michael; Hinnen, Paul; de Graaf, Roelof; van der Laan, Hans; Padiy, Alexander; Menchtchikov, Boris

    2013-04-01

    Immersion lithography is being extended to the 20-nm and 14-nm node and the lithography performance requirements need to be tightened further to enable this shrink. In this paper we present an integral method to enable high-order fieldto- field corrections for both imaging and overlay, and we show that this method improves the performance with 20% - 50%. The lithography architecture we build for these higher order corrections connects the dynamic scanner actuators with the angle resolved scatterometer via a separate application server. Improvements of CD uniformity are based on enabling the use of freeform intra-field dose actuator and field-to-field control of focus. The feedback control loop uses CD and focus targets placed on the production mask. For the overlay metrology we use small in-die diffraction based overlay targets. Improvements of overlay are based on using the high order intra-field correction actuators on a field-tofield basis. We use this to reduce the machine matching error, extending the heating control and extending the correction capability for process induced errors.

  7. Topological order following a quantum quench

    NASA Astrophysics Data System (ADS)

    Tsomokos, Dimitris I.; Hamma, Alioscia; Zhang, Wen; Haas, Stephan; Fazio, Rosario

    2009-12-01

    We determine the conditions under which topological order survives a rapid quantum quench. Specifically, we consider the case where a quantum spin system is prepared in the ground state of the toric code model and, after the quench, it evolves with a Hamiltonian that does not support topological order. We provide analytical results supported by numerical evidence for a variety of quench Hamiltonians. The robustness of topological order under nonequilibrium situations is tested by studying the topological entropy and a dynamical measure, which makes use of the similarity between partial density matrices obtained from different topological sectors.

  8. DOE`s nation-wide system for access control can solve problems for the federal government

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Callahan, S.; Tomes, D.; Davis, G.

    1996-07-01

    The U.S. Department of Energy`s (DOE`s) ongoing efforts to improve its physical and personnel security systems while reducing its costs, provide a model for federal government visitor processing. Through the careful use of standardized badges, computer databases, and networks of automated access control systems, the DOE is increasing the security associated with travel throughout the DOE complex, and at the same time, eliminating paperwork, special badging, and visitor delays. The DOE is also improving badge accountability, personnel identification assurance, and access authorization timeliness and accuracy. Like the federal government, the DOE has dozens of geographically dispersed locations run by manymore » different contractors operating a wide range of security systems. The DOE has overcome these obstacles by providing data format standards, a complex-wide virtual network for security, the adoption of a standard high security system, and an open-systems-compatible link for any automated access control system. If the location`s level of security requires it, positive visitor identification is accomplished by personal identification number (PIN) and/or by biometrics. At sites with automated access control systems, this positive identification is integrated into the portals.« less

  9. 16 CFR 1513.3 - Requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Requirements. 1513.3 Section 1513.3... REQUIREMENTS FOR BUNK BEDS § 1513.3 Requirements. (a) Guardrails. (1) Any bunk bed shall provide at least two... bed. This requirement does not prohibit a wall-side guardrail that terminates in a quarter-circle bend...

  10. 16 CFR 1513.3 - Requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Requirements. 1513.3 Section 1513.3... REQUIREMENTS FOR BUNK BEDS § 1513.3 Requirements. (a) Guardrails. (1) Any bunk bed shall provide at least two... bed. This requirement does not prohibit a wall-side guardrail that terminates in a quarter-circle bend...

  11. The actual scaling of a nominally third-order Reynolds stress

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Krommes, J. A., E-mail: krommes@princeton.edu; Hammett, G. W., E-mail: hammett@princeton.edu

    2014-05-15

    It is shown that a particular higher-order Reynolds stress arising from a term in the third-order gyrokinetic Hamiltonian is smaller than it nominally appears to be. However, it does not follow that all third-order terms are unimportant. The discussion is relevant to the ongoing debate about the importance of higher-order terms in the gyrokinetic theory of momentum transport.

  12. Digital image comparison by subtracting contextual transformations—percentile rank order differentiation

    USGS Publications Warehouse

    Wehde, M. E.

    1995-01-01

    The common method of digital image comparison by subtraction imposes various constraints on the image contents. Precise registration of images is required to assure proper evaluation of surface locations. The attribute being measured and the calibration and scaling of the sensor are also important to the validity and interpretability of the subtraction result. Influences of sensor gains and offsets complicate the subtraction process. The presence of any uniform systematic transformation component in one of two images to be compared distorts the subtraction results and requires analyst intervention to interpret or remove it. A new technique has been developed to overcome these constraints. Images to be compared are first transformed using the cumulative relative frequency as a transfer function. The transformed images represent the contextual relationship of each surface location with respect to all others within the image. The process of differentiating between the transformed images results in a percentile rank ordered difference. This process produces consistent terrain-change information even when the above requirements necessary for subtraction are relaxed. This technique may be valuable to an appropriately designed hierarchical terrain-monitoring methodology because it does not require human participation in the process.

  13. Low-order aberration sensitivity of eighth-order coronagraph masks

    NASA Technical Reports Server (NTRS)

    Shaklan, Stuart B.; Green, Joseph J.

    2005-01-01

    In a recent paper, Kuchner, Crepp, and Ge describe new image-plane coronagraph mask designs that reject to eighth order the leakage of starlight caused by image motion at the mask, resulting in a substantial relaxation of image centroiding requirements compared to previous fourth-order and second-order masks. They also suggest that the new masks are effective at rejecting leakage caused by low-order aberrations (e.g., focus, coma, and astigmatism). In this paper, we derive the sensitivity of eighth-order masks to aberrations of any order and provide simulations of coronagraph behavior in the presence of optical aberrations.We find that the masks leak light as the fourth power of focus, astigmatism, coma, and trefoil. This has tremendous performance advantages for the Terrestrial Planet Finder Coronagraph.

  14. 48 CFR 11.101 - Order of precedence for requirements documents.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    .... (2) Performance-oriented documents (e.g., a PWS or SOO). (See 2.101.) (3) Detailed design-oriented... requirements documents. 11.101 Section 11.101 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Selecting and Developing Requirements Documents 11...

  15. Does Higher-Order Thinking Impinge on Learner-Centric Digital Approach?

    ERIC Educational Resources Information Center

    Mathew, Bincy; Raja, B. William Dharma

    2015-01-01

    Humans are social beings and the social cognition focuses on how one form impressions of other people, interpret the meaning of other people's behaviour and how people's behaviour is affected by our attitudes. The school provides complex social situations and in order to thrive, students must possess social cognition, the process of thinking about…

  16. 40 CFR 90.808 - Ordered recall provisions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...-Related Defect Reporting Requirements, Voluntary Emission Recall Program, Ordered Recalls § 90.808 Ordered... manufacturer shall comply in all respects with the requirements of this subpart. (2) Any notification required... regulations at § 90.804. Such manufacturer is subject to the reporting and recordkeeping requirements of § 90...

  17. De novo centriole formation in human cells is error-prone and does not require SAS-6 self-assembly.

    PubMed

    Wang, Won-Jing; Acehan, Devrim; Kao, Chien-Han; Jane, Wann-Neng; Uryu, Kunihiro; Tsou, Meng-Fu Bryan

    2015-11-26

    Vertebrate centrioles normally propagate through duplication, but in the absence of preexisting centrioles, de novo synthesis can occur. Consistently, centriole formation is thought to strictly rely on self-assembly, involving self-oligomerization of the centriolar protein SAS-6. Here, through reconstitution of de novo synthesis in human cells, we surprisingly found that normal looking centrioles capable of duplication and ciliation can arise in the absence of SAS-6 self-oligomerization. Moreover, whereas canonically duplicated centrioles always form correctly, de novo centrioles are prone to structural errors, even in the presence of SAS-6 self-oligomerization. These results indicate that centriole biogenesis does not strictly depend on SAS-6 self-assembly, and may require preexisting centrioles to ensure structural accuracy, fundamentally deviating from the current paradigm.

  18. Advanced Scientific Computing Research Network Requirements: ASCR Network Requirements Review Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bacon, Charles; Bell, Greg; Canon, Shane

    The Energy Sciences Network (ESnet) is the primary provider of network connectivity for the U.S. Department of Energy (DOE) Office of Science (SC), the single largest supporter of basic research in the physical sciences in the United States. In support of SC programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs that it serves. This focus has helped ESnet to be a highly successful enabler of scientific discovery for over 25 years. In October 2012, ESnet and the Office of Advanced Scientific Computing Research (ASCR) of the DOE SCmore » organized a review to characterize the networking requirements of the programs funded by the ASCR program office. The requirements identified at the review are summarized in the Findings section, and are described in more detail in the body of the report.« less

  19. Does Gender Influence Electroconvulsive Therapy Sessions Required across Psychiatric Diagnoses? A 5-Year Experience from a Single Center

    PubMed Central

    Manohar, Harshini; Subramanian, Karthick; Menon, Vikas; Kattimani, Shivanand

    2017-01-01

    Context: There is a paucity of systematic data reflecting the practice of electroconvulsive therapy (ECT) from developing countries. Aim: We aimed to identify the number of ECT sessions required to yield response and gender diffeferences in the number of sessions across various diagnostic categories. Setting and Design: A record-based study from a teaching cum tertiary care hospital in South India. Subjects and Methods: Case records of patients who received modified ECT from January 2011 to January 2016 were reviewed. The sociodemographic details and ECT-related data were collected. Psychiatric diagnoses were ascertained as per the International Classification of Diseases, 10th Revision criteria. Statistical Analysis Used: Kruskal–Wallis test and Mann–Whitney U-test. Results: Among 148 patients, 82 (55.4%) had mood disorder (bipolar disorder and recurrent depressive disorder), 43 (29.1%) had schizophrenia, and 22 (14.9%) had other acute and transient psychotic disorders (ATPDs). Patients with mood disorders, schizophrenia, and other ATPD received 7.3 (± 3.8), 9.7 (± 6.1), and 5.4 (± 2.0) ECT sessions, respectively, to achieve response. There was no gender difference in the number of sessions received. Conclusion: Our findings show that number of ECT sessions required to yield response may be disorder-specific. Gender does not influence the ECT dose requirement. Variations in ECT parameters across settings may limit the generalizability of results. PMID:28694625

  20. 40 CFR 763.122 - What does this subpart require me to do?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT ASBESTOS Asbestos Worker Protection § 763.122 What does this subpart... standards in 29 CFR 1910.1001. (c) Repair, cleaning, or replacement of asbestos-containing clutch plates and brake pads, shoes, and linings, or removal of asbestos-containing residue from brake drums or clutch...

  1. 40 CFR 763.122 - What does this subpart require me to do?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT ASBESTOS Asbestos Worker Protection § 763.122 What does this subpart... standards in 29 CFR 1910.1001. (c) Repair, cleaning, or replacement of asbestos-containing clutch plates and brake pads, shoes, and linings, or removal of asbestos-containing residue from brake drums or clutch...

  2. 40 CFR 763.122 - What does this subpart require me to do?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT ASBESTOS Asbestos Worker Protection § 763.122 What does this subpart... standards in 29 CFR 1910.1001. (c) Repair, cleaning, or replacement of asbestos-containing clutch plates and brake pads, shoes, and linings, or removal of asbestos-containing residue from brake drums or clutch...

  3. 40 CFR 763.122 - What does this subpart require me to do?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT ASBESTOS Asbestos Worker Protection § 763.122 What does this subpart... standards in 29 CFR 1910.1001. (c) Repair, cleaning, or replacement of asbestos-containing clutch plates and brake pads, shoes, and linings, or removal of asbestos-containing residue from brake drums or clutch...

  4. 40 CFR 763.122 - What does this subpart require me to do?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT ASBESTOS Asbestos Worker Protection § 763.122 What does this subpart... standards in 29 CFR 1910.1001. (c) Repair, cleaning, or replacement of asbestos-containing clutch plates and brake pads, shoes, and linings, or removal of asbestos-containing residue from brake drums or clutch...

  5. 16 CFR 1213.3 - Requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Requirements. 1213.3 Section 1213.3... STANDARD FOR ENTRAPMENT HAZARDS IN BUNK BEDS § 1213.3 Requirements. (a) Guardrails. (1) Any bunk bed shall... instructions is on the bed. This requirement does not prohibit a wall-side guardrail that terminates in a...

  6. 16 CFR 1213.3 - Requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Requirements. 1213.3 Section 1213.3... STANDARD FOR ENTRAPMENT HAZARDS IN BUNK BEDS § 1213.3 Requirements. (a) Guardrails. (1) Any bunk bed shall... instructions is on the bed. This requirement does not prohibit a wall-side guardrail that terminates in a...

  7. 3 CFR 13517 - Executive Order 13517 of October 30, 2009. Amendments to Executive Orders 13183 and 13494

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... initiatives that benefit Puerto Rico; provide advice and recommendations to the President and the Congress on..., or concerning the manner of exercising, the right to organize and bargain collectively), including.... 31.205-21.” Sec. 3. This order is not intended to, and does not, create any right or benefit...

  8. DOE standard: The Department of Energy Laboratory Accreditation Program for radiobioassay

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1998-12-01

    This technical standard describes the US Department of Energy Laboratory Accreditation Program (DOELAP) for Radiobioassay, for use by the US Department of Energy (DOE) and DOE Contractor radiobioassay programs. This standard is intended to be used in conjunction with the general administrative technical standard that describes the overall DOELAP accreditation process--DOE-STD-1111-98, Department of Energy Laboratory Accreditation Program Administration. This technical standard pertains to radiobioassay service laboratories that provide either direct or indirect (in vivo or in vitro) radiobioassay measurements in support of internal dosimetry programs at DOE facilities or for DOE and DOE contractors. Similar technical standards have been developedmore » for other DOELAP dosimetry programs. This program consists of providing an accreditation to DOE radiobioassay programs based on successful completion of a performance-testing process and an on-site evaluation by technical experts. This standard describes the technical requirements and processes specific to the DOELAP Radiobioassay Accreditation Program as required by 10 CFR 835 and as specified generically in DOE-STD-1111-98.« less

  9. Spatiotemporal requirements of the Hainan gibbon: Does home range constrain recovery of the world's rarest ape?

    PubMed

    Bryant, Jessica V; Zeng, Xingyuan; Hong, Xiaojiang; Chatterjee, Helen J; Turvey, Samuel T

    2017-03-01

    Conservation management requires an evidence-based approach, as uninformed decisions can signify the difference between species recovery and loss. The Hainan gibbon, the world's rarest ape, reportedly exploits the largest home range of any gibbon species, with these apparently large spatial requirements potentially limiting population recovery. However, previous home range assessments rarely reported survey methods, effort, or analytical approaches, hindering critical evaluation of estimate reliability. For extremely rare species where data collection is challenging, it also is unclear what impact such limitations have on estimating home range requirements. We re-evaluated Hainan gibbon spatial ecology using 75 hr of observations from 35 contact days over 93 field-days across dry (November 2010-February 2011) and wet (June 2011-September 2011) seasons. We calculated home range area for three social groups (N = 21 individuals) across the sampling period, seasonal estimates for one group (based on 24 days of observation; 12 days per season), and between-group home range overlap using multiple approaches (Minimum Convex Polygon, Kernel Density Estimation, Local Convex Hull, Brownian Bridge Movement Model), and assessed estimate reliability and representativeness using three approaches (Incremental Area Analysis, spatial concordance, and exclusion of expected holes). We estimated a yearly home range of 1-2 km 2 , with 1.49 km 2 closest to the median of all estimates. Although Hainan gibbon spatial requirements are relatively large for gibbons, our new estimates are smaller than previous estimates used to explain the species' limited recovery, suggesting that habitat availability may be less important in limiting population growth. We argue that other ecological, genetic, and/or anthropogenic factors are more likely to constrain Hainan gibbon recovery, and conservation attention should focus on elucidating and managing these factors. Re-evaluation reveals

  10. Sleep's Influence on a Reflexive Form of Memory That Does Not Require Voluntary Attention

    PubMed Central

    Sheth, Bhavin R.; Serranzana, Andrew; Anjum, Syed F.; Khan, Murtuza

    2012-01-01

    Study Objectives: Studies to date have examined the influence of sleep on forms of memory that require voluntary attention. The authors examine the influence of sleep on a form of memory that is acquired by passive viewing. Design: Induction of the McCollough effect, and measurement of perceptual color bias before and after induction, and before and after intervening sleep, wake, or visual deprivation. Setting: Sound-attenuated sleep research room. Participants: 13 healthy volunteers (mean age = 23 years; age range = 18–31 years) with normal or corrected-to-normal vision. Interventions: N/A. Measurements and Results:) Encoding: sleep preceded adaptation. On separate nights, each participant slept for an average of 0 (wake), 1, 2, 4, or 7 hr (complete sleep). Upon awakening, the participant's baseline perceptual color bias was measured. Then, he or she viewed an adapter consisting of alternating red/horizontal and green/vertical gratings for 5 min. Color bias was remeasured. The strength of the aftereffect is the postadaptation color bias relative to baseline. A strong orientation contingent color aftereffect was observed in all participants, but total sleep duration (TSD) prior to the adaptation did not modulate aftereffect strength. Further, prior sleep provided no benefit over prior wake. Retention: sleep followed adaptation. The procedure was similar except that adaptation preceded sleep. Postadaptation sleep, irrespective of its duration (1, 3, 5, or 7 hr), arrested aftereffect decay. By contrast, aftereffect decay was arrested during subsequent wake only if the adapted eye was visually deprived. Conclusions: Sleep as well as passive sensory deprivation enables the retention of a color aftereffect. Sleep shelters this reflexive form of memory in a manner akin to preventing sensory interference. Citation: Sheth BR; Serranzana A; Anjum SF; Khan M. Sleep's influence on a reflexive form of memory that does not require voluntary attention. SLEEP 2012

  11. Does user-centred design affect the efficiency, usability and safety of CPOE order sets?

    PubMed

    Chan, Julie; Shojania, Kaveh G; Easty, Anthony C; Etchells, Edward E

    2011-05-01

    Application of user-centred design principles to Computerized provider order entry (CPOE) systems may improve task efficiency, usability or safety, but there is limited evaluative research of its impact on CPOE systems. We evaluated the task efficiency, usability, and safety of three order set formats: our hospital's planned CPOE order sets (CPOE Test), computer order sets based on user-centred design principles (User Centred Design), and existing pre-printed paper order sets (Paper). 27 staff physicians, residents and medical students. Sunnybrook Health Sciences Centre, an academic hospital in Toronto, Canada. Methods Participants completed four simulated order set tasks with three order set formats (two CPOE Test tasks, one User Centred Design, and one Paper). Order of presentation of order set formats and tasks was randomized. Users received individual training for the CPOE Test format only. Completion time (efficiency), requests for assistance (usability), and errors in the submitted orders (safety). 27 study participants completed 108 order sets. Mean task times were: User Centred Design format 273 s, Paper format 293 s (p=0.73 compared to UCD format), and CPOE Test format 637 s (p<0.0001 compared to UCD format). Users requested assistance in 31% of the CPOE Test format tasks, whereas no assistance was needed for the other formats (p<0.01). There were no significant differences in number of errors between formats. The User Centred Design format was more efficient and usable than the CPOE Test format even though training was provided for the latter. We conclude that application of user-centred design principles can enhance task efficiency and usability, increasing the likelihood of successful implementation.

  12. Renormalization of dijet operators at order 1 /Q 2 in soft-collinear effective theory

    NASA Astrophysics Data System (ADS)

    Goerke, Raymond; Inglis-Whalen, Matthew

    2018-05-01

    We make progress towards resummation of power-suppressed logarithms in dijet event shapes such as thrust, which have the potential to improve high-precision fits for the value of the strong coupling constant. Using a newly developed formalism for Soft-Collinear Effective Theory (SCET), we identify and compute the anomalous dimensions of all the operators that contribute to event shapes at order 1 /Q 2. These anomalous dimensions are necessary to resum power-suppressed logarithms in dijet event shape distributions, although an additional matching step and running of observable-dependent soft functions will be necessary to complete the resummation. In contrast to standard SCET, the new formalism does not make reference to modes or λ-scaling. Since the formalism does not distinguish between collinear and ultrasoft degrees of freedom at the matching scale, fewer subleading operators are required when compared to recent similar work. We demonstrate how the overlap subtraction prescription extends to these subleading operators.

  13. 45 CFR 16.1 - What this part does.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false What this part does. 16.1 Section 16.1 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PROCEDURES OF THE DEPARTMENTAL GRANT APPEALS BOARD § 16.1 What this part does. This part contains requirements and procedures...

  14. Generalized Gibbs state with modified Redfield solution: Exact agreement up to second order

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thingna, Juzar; Wang, Jian-Sheng; Haenggi, Peter

    A novel scheme for the steady state solution of the standard Redfield quantum master equation is developed which yields agreement with the exact result for the corresponding reduced density matrix up to second order in the system-bath coupling strength. We achieve this objective by use of an analytic continuation of the off-diagonal matrix elements of the Redfield solution towards its diagonal limit. Notably, our scheme does not require the provision of yet higher order relaxation tensors. Testing this modified method for a heat bath consisting of a collection of harmonic oscillators we assess that the system relaxes towards its correctmore » coupling-dependent, generalized quantum Gibbs state in second order. We numerically compare our formulation for a damped quantum harmonic system with the nonequilibrium Green's function formalism: we find good agreement at low temperatures for coupling strengths that are even larger than expected from the very regime of validity of the second-order Redfield quantum master equation. Yet another advantage of our method is that it markedly reduces the numerical complexity of the problem; thus, allowing to study efficiently large-sized system Hilbert spaces.« less

  15. 30 CFR 243.8 - When will MMS suspend my obligation to comply with an order?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...), and: (1) If the amount under appeal is less than $10,000 or does not require payment of a specified... the amount under appeal is less than $1,000 or does not require payment, MMS will suspend your... paying any demanded amount or complying with any other requirement pending appeal. However, voluntarily...

  16. Does user-centred design affect the efficiency, usability and safety of CPOE order sets?

    PubMed Central

    Chan, Julie; Shojania, Kaveh G; Easty, Anthony C

    2011-01-01

    Background Application of user-centred design principles to Computerized provider order entry (CPOE) systems may improve task efficiency, usability or safety, but there is limited evaluative research of its impact on CPOE systems. Objective We evaluated the task efficiency, usability, and safety of three order set formats: our hospital's planned CPOE order sets (CPOE Test), computer order sets based on user-centred design principles (User Centred Design), and existing pre-printed paper order sets (Paper). Participants 27staff physicians, residents and medical students. Setting Sunnybrook Health Sciences Centre, an academic hospital in Toronto, Canada. Methods Participants completed four simulated order set tasks with three order set formats (two CPOE Test tasks, one User Centred Design, and one Paper). Order of presentation of order set formats and tasks was randomized. Users received individual training for the CPOE Test format only. Main Measures Completion time (efficiency), requests for assistance (usability), and errors in the submitted orders (safety). Results 27 study participants completed 108 order sets. Mean task times were: User Centred Design format 273 s, Paper format 293 s (p=0.73 compared to UCD format), and CPOE Test format 637 s (p<0.0001 compared to UCD format). Users requested assistance in 31% of the CPOE Test format tasks, whereas no assistance was needed for the other formats (p<0.01). There were no significant differences in number of errors between formats. Conclusions The User Centred Design format was more efficient and usable than the CPOE Test format even though training was provided for the latter. We conclude that application of user-centred design principles can enhance task efficiency and usability, increasing the likelihood of successful implementation. PMID:21486886

  17. Transitive Responding in Hooded Crows Requires Linearly Ordered Stimuli

    ERIC Educational Resources Information Center

    Lazareva, Olga F.; Smirnova, Anna A.; Bagozkaja, Maria S.; Zorina, Zoya A.; Rayevsky, Vladimir V.; Wasserman, Edward A.

    2004-01-01

    Eight crows were taught to discriminate overlapping pairs of visual stimuli (A+ B-, B+ C-, C+ D-, and D+ E-). For 4 birds, the stimuli were colored cards with a circle of the same color on the reverse side whose diameter decreased from A to E (ordered feedback group). These circles were made available for comparison to potentially help the crows…

  18. Data Crosscutting Requirements Review

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kleese van Dam, Kerstin; Shoshani, Arie; Plata, Charity

    2013-04-01

    In April 2013, a diverse group of researchers from the U.S. Department of Energy (DOE) scientific community assembled to assess data requirements associated with DOE-sponsored scientific facilities and large-scale experiments. Participants in the review included facilities staff, program managers, and scientific experts from the offices of Basic Energy Sciences, Biological and Environmental Research, High Energy Physics, and Advanced Scientific Computing Research. As part of the meeting, review participants discussed key issues associated with three distinct aspects of the data challenge: 1) processing, 2) management, and 3) analysis. These discussions identified commonalities and differences among the needs of varied scientific communities.more » They also helped to articulate gaps between current approaches and future needs, as well as the research advances that will be required to close these gaps. Moreover, the review provided a rare opportunity for experts from across the Office of Science to learn about their collective expertise, challenges, and opportunities. The "Data Crosscutting Requirements Review" generated specific findings and recommendations for addressing large-scale data crosscutting requirements.« less

  19. Robust and Accurate Shock Capturing Method for High-Order Discontinuous Galerkin Methods

    NASA Technical Reports Server (NTRS)

    Atkins, Harold L.; Pampell, Alyssa

    2011-01-01

    A simple yet robust and accurate approach for capturing shock waves using a high-order discontinuous Galerkin (DG) method is presented. The method uses the physical viscous terms of the Navier-Stokes equations as suggested by others; however, the proposed formulation of the numerical viscosity is continuous and compact by construction, and does not require the solution of an auxiliary diffusion equation. This work also presents two analyses that guided the formulation of the numerical viscosity and certain aspects of the DG implementation. A local eigenvalue analysis of the DG discretization applied to a shock containing element is used to evaluate the robustness of several Riemann flux functions, and to evaluate algorithm choices that exist within the underlying DG discretization. A second analysis examines exact solutions to the DG discretization in a shock containing element, and identifies a "model" instability that will inevitably arise when solving the Euler equations using the DG method. This analysis identifies the minimum viscosity required for stability. The shock capturing method is demonstrated for high-speed flow over an inviscid cylinder and for an unsteady disturbance in a hypersonic boundary layer. Numerical tests are presented that evaluate several aspects of the shock detection terms. The sensitivity of the results to model parameters is examined with grid and order refinement studies.

  20. 8 CFR 1216.2 - Notification requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... second time of the requirement that the alien and the petitioning spouse or alien entrepreneur must file... does not relieve the alien and the petitioning spouse, or alien entrepreneur of the requirement to file...

  1. 48 CFR 970.2670-1 - Requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Requirements. 970.2670-1... REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Other Socioeconomic Programs 970.2670-1 Requirements. The goal requirements of section 3021 of the Energy Policy Act of 1992, and the attendant reporting...

  2. 48 CFR 970.2670-1 - Requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Requirements. 970.2670-1... REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Other Socioeconomic Programs 970.2670-1 Requirements. The goal requirements of section 3021 of the Energy Policy Act of 1992, and the attendant reporting...

  3. Authorization basis requirements comparison report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brantley, W.M.

    The TWRS Authorization Basis (AB) consists of a set of documents identified by TWRS management with the concurrence of DOE-RL. Upon implementation of the TWRS Basis for Interim Operation (BIO) and Technical Safety Requirements (TSRs), the AB list will be revised to include the BIO and TSRs. Some documents that currently form part of the AB will be removed from the list. This SD identifies each - requirement from those documents, and recommends a disposition for each to ensure that necessary requirements are retained when the AB is revised to incorporate the BIO and TSRs. This SD also identifies documentsmore » that will remain part of the AB after the BIO and TSRs are implemented. This document does not change the AB, but provides guidance for the preparation of change documentation.« less

  4. Dispersion of speckle suppression efficiency for binary DOE structures: spectral domain and coherent matrix approaches.

    PubMed

    Lapchuk, Anatoliy; Prygun, Olexandr; Fu, Minglei; Le, Zichun; Xiong, Qiyuan; Kryuchyn, Andriy

    2017-06-26

    We present the first general theoretical description of speckle suppression efficiency based on an active diffractive optical element (DOE). The approach is based on spectral analysis of diffracted beams and a coherent matrix. Analytical formulae are obtained for the dispersion of speckle suppression efficiency using different DOE structures and different DOE activation methods. We show that a one-sided 2D DOE structure has smaller speckle suppression range than a two-sided 1D DOE structure. Both DOE structures have sufficient speckle suppression range to suppress low-order speckles in the entire visible range, but only the two-sided 1D DOE can suppress higher-order speckles. We also show that a linear shift 2D DOE in a laser projector with a large numerical aperture has higher effective speckle suppression efficiency than the method using switching or step-wise shift DOE structures. The generalized theoretical models elucidate the mechanism and practical realization of speckle suppression.

  5. 10 CFR 727.6 - What are the obligations of a DOE contractor?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... COMPUTERS § 727.6 What are the obligations of a DOE contractor? (a) A DOE contractor must ensure that... computer unless the DOE contractor has obtained a written acknowledgment and consent by each contractor or... violates the requirements of this section with regard to a DOE computer with Restricted Data or other...

  6. 10 CFR 727.6 - What are the obligations of a DOE contractor?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... COMPUTERS § 727.6 What are the obligations of a DOE contractor? (a) A DOE contractor must ensure that... computer unless the DOE contractor has obtained a written acknowledgment and consent by each contractor or... violates the requirements of this section with regard to a DOE computer with Restricted Data or other...

  7. 10 CFR 727.6 - What are the obligations of a DOE contractor?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... COMPUTERS § 727.6 What are the obligations of a DOE contractor? (a) A DOE contractor must ensure that... computer unless the DOE contractor has obtained a written acknowledgment and consent by each contractor or... violates the requirements of this section with regard to a DOE computer with Restricted Data or other...

  8. 10 CFR 727.6 - What are the obligations of a DOE contractor?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... COMPUTERS § 727.6 What are the obligations of a DOE contractor? (a) A DOE contractor must ensure that... computer unless the DOE contractor has obtained a written acknowledgment and consent by each contractor or... violates the requirements of this section with regard to a DOE computer with Restricted Data or other...

  9. 10 CFR 727.6 - What are the obligations of a DOE contractor?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... COMPUTERS § 727.6 What are the obligations of a DOE contractor? (a) A DOE contractor must ensure that... computer unless the DOE contractor has obtained a written acknowledgment and consent by each contractor or... violates the requirements of this section with regard to a DOE computer with Restricted Data or other...

  10. Second-Order Sensitivity Analysis of Uncollided Particle Contributions to Radiation Detector Responses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cacuci, Dan G.; Favorite, Jeffrey A.

    This work presents an application of Cacuci’s Second-Order Adjoint Sensitivity Analysis Methodology (2nd-ASAM) to the simplified Boltzmann equation that models the transport of uncollided particles through a medium to compute efficiently and exactly all of the first- and second-order derivatives (sensitivities) of a detector’s response with respect to the system’s isotopic number densities, microscopic cross sections, source emission rates, and detector response function. The off-the-shelf PARTISN multigroup discrete ordinates code is employed to solve the equations underlying the 2nd-ASAM. The accuracy of the results produced using PARTISN is verified by using the results of three test configurations: (1) a homogeneousmore » sphere, for which the response is the exactly known total uncollided leakage, (2) a multiregion two-dimensional (r-z) cylinder, and (3) a two-region sphere for which the response is a reaction rate. For the homogeneous sphere, results for the total leakage as well as for the respective first- and second-order sensitivities are in excellent agreement with the exact benchmark values. For the nonanalytic problems, the results obtained by applying the 2nd-ASAM to compute sensitivities are in excellent agreement with central-difference estimates. The efficiency of the 2nd-ASAM is underscored by the fact that, for the cylinder, only 12 adjoint PARTISN computations were required by the 2nd-ASAM to compute all of the benchmark’s 18 first-order sensitivities and 224 second-order sensitivities, in contrast to the 877 PARTISN calculations needed to compute the respective sensitivities using central finite differences, and this number does not include the additional calculations that were required to find appropriate values of the perturbations to use for the central differences.« less

  11. Second-Order Sensitivity Analysis of Uncollided Particle Contributions to Radiation Detector Responses

    DOE PAGES

    Cacuci, Dan G.; Favorite, Jeffrey A.

    2018-04-06

    This work presents an application of Cacuci’s Second-Order Adjoint Sensitivity Analysis Methodology (2nd-ASAM) to the simplified Boltzmann equation that models the transport of uncollided particles through a medium to compute efficiently and exactly all of the first- and second-order derivatives (sensitivities) of a detector’s response with respect to the system’s isotopic number densities, microscopic cross sections, source emission rates, and detector response function. The off-the-shelf PARTISN multigroup discrete ordinates code is employed to solve the equations underlying the 2nd-ASAM. The accuracy of the results produced using PARTISN is verified by using the results of three test configurations: (1) a homogeneousmore » sphere, for which the response is the exactly known total uncollided leakage, (2) a multiregion two-dimensional (r-z) cylinder, and (3) a two-region sphere for which the response is a reaction rate. For the homogeneous sphere, results for the total leakage as well as for the respective first- and second-order sensitivities are in excellent agreement with the exact benchmark values. For the nonanalytic problems, the results obtained by applying the 2nd-ASAM to compute sensitivities are in excellent agreement with central-difference estimates. The efficiency of the 2nd-ASAM is underscored by the fact that, for the cylinder, only 12 adjoint PARTISN computations were required by the 2nd-ASAM to compute all of the benchmark’s 18 first-order sensitivities and 224 second-order sensitivities, in contrast to the 877 PARTISN calculations needed to compute the respective sensitivities using central finite differences, and this number does not include the additional calculations that were required to find appropriate values of the perturbations to use for the central differences.« less

  12. 40 CFR 51.15 - What data does my state need to report to EPA?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 2 2011-07-01 2011-07-01 false What data does my state need to report... PROGRAMS REQUIREMENTS FOR PREPARATION, ADOPTION, AND SUBMITTAL OF IMPLEMENTATION PLANS Air Emissions Reporting Requirements Specific Reporting Requirements § 51.15 What data does my state need to report to EPA...

  13. Design optimization of hydraulic turbine draft tube based on CFD and DOE method

    NASA Astrophysics Data System (ADS)

    Nam, Mun chol; Dechun, Ba; Xiangji, Yue; Mingri, Jin

    2018-03-01

    In order to improve performance of the hydraulic turbine draft tube in its design process, the optimization for draft tube is performed based on multi-disciplinary collaborative design optimization platform by combining the computation fluid dynamic (CFD) and the design of experiment (DOE) in this paper. The geometrical design variables are considered as the median section in the draft tube and the cross section in its exit diffuser and objective function is to maximize the pressure recovery factor (Cp). Sample matrixes required for the shape optimization of the draft tube are generated by optimal Latin hypercube (OLH) method of the DOE technique and their performances are evaluated through computational fluid dynamic (CFD) numerical simulation. Subsequently the main effect analysis and the sensitivity analysis of the geometrical parameters of the draft tube are accomplished. Then, the design optimization of the geometrical design variables is determined using the response surface method. The optimization result of the draft tube shows a marked performance improvement over the original.

  14. DOE standard 3009 - a reasoned, practical approach to integrating criticality safety into SARs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vessard, S.G.

    1995-12-31

    In the past there have been efforts by the U.S. Department of Energy (DOE) to provide guidance on those elements that should be included in a facility`s safety analysis report (SAR). In particular, there are two DOE Orders (5480.23, {open_quotes}Nuclear Safety Analysis Reports,{close_quotes} and 5480.24, {open_quotes}Nuclear Criticality Safety{close_quotes}), an interpretive guidance document (NE-70, Interpretive Guidance for DOE Order 5480.24, {open_quotes}Nuclear Criticality Safety{close_quotes}), and DOE Standard DOE-STD-3009-94 {open_quotes}Preparation Guide for U.S. Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports.{close_quotes} Of these, the most practical and useful (pertaining to the application of criticality safety) is DOE-STD-3009-94. This paper is a reviewmore » of Chapters 3, 4, and 6 of this standard and how they provide very clear, helpful, and reasoned criticality safety guidance.« less

  15. 20 CFR 645.200 - What does this subpart cover?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What does this subpart cover? 645.200 Section 645.200 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING WELFARE-TO-WORK GRANTS General Program and Administrative Requirements § 645.200 What does this...

  16. 33 CFR 149.300 - What does this subpart do?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false What does this subpart do? 149.300 Section 149.300 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY....300 What does this subpart do? This subpart provides requirements for lifesaving equipment on...

  17. 33 CFR 149.300 - What does this subpart do?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false What does this subpart do? 149.300 Section 149.300 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY....300 What does this subpart do? This subpart provides requirements for lifesaving equipment on...

  18. Explosives Safety Requirements Manual

    DOT National Transportation Integrated Search

    1996-03-29

    This Manual describes the Department of Energy's (DOE's) explosives safety requirements applicable to operations involving the development, testing, handling, and processing of explosives or assemblies containing explosives. It is intended to reflect...

  19. BRD usability requirements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Deshpande, Alina

    2015-03-12

    This document describes the usability requirements for the Biosurveillance resource directory (BRD); that is, who will be using the tool and what tasks they will be using it for. It does not include information on technical implementation (e.g., whether specific information is contained in the database or pulled on demand from other sources). It also avoids specific design ideas (such as widget descriptions) unless they are necessary to illustrate a requirement.

  20. 10 CFR 1015.405 - Discharge of indebtedness; reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... (b) 31 U.S.C. 3711(i) requires DOE to sell a delinquent non-tax debt upon termination of collection... indebtedness; reporting requirements. (a) Before discharging a delinquent debt (also referred to as a close out of the debt), DOE shall take all appropriate steps to collect the debt in accordance with 31 U.S.C...

  1. 42 CFR 425.310 - Marketing requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 3 2014-10-01 2014-10-01 false Marketing requirements. 425.310 Section 425.310... Protections § 425.310 Marketing requirements. (a) File and use. Marketing materials and activities, as defined...) The ACO certifies compliance with all the marketing requirements under this section; and (2) CMS does...

  2. 42 CFR 425.310 - Marketing requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 3 2013-10-01 2013-10-01 false Marketing requirements. 425.310 Section 425.310... Protections § 425.310 Marketing requirements. (a) File and use. Marketing materials and activities, as defined...) The ACO certifies compliance with all the marketing requirements under this section; and (2) CMS does...

  3. 42 CFR 425.310 - Marketing requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 3 2012-10-01 2012-10-01 false Marketing requirements. 425.310 Section 425.310... Protections § 425.310 Marketing requirements. (a) File and use. Marketing materials and activities, as defined...) The ACO certifies compliance with all the marketing requirements under this section; and (2) CMS does...

  4. DOE Fire Protection Handbook, Volume I

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    The Department of Energy (DOE) Fire Protection Program is delineated in a number of source documents including; the Code of Federal Regulations (CFR), DOE Policy Statements and Orders, DOE and national consensus standards (such as those promulgated by the National Fire Protection Association), and supplementary guidance, This Handbook is intended to bring together in one location as much of this material as possible to facilitate understanding and ease of use. The applicability of any of these directives to individual Maintenance and Operating Contractors or to given facilities and operations is governed by existing contracts. Questions regarding applicability should be directedmore » to the DOE Authority Having Jurisdiction for fire safety. The information provided within includes copies of those DOE directives that are directly applicable to the implementation of a comprehensive fire protection program. They are delineated in the Table of Contents. The items marked with an asterisk (*) are included on the disks in WordPerfect 5.1 format, with the filename noted below. The items marked with double asterisks are provided as hard copies as well as on the disk. For those using MAC disks, the files are in Wordperfect 2.1 for MAC.« less

  5. Extended observer based on adaptive second order sliding mode control for a fixed wing UAV.

    PubMed

    Castañeda, Herman; Salas-Peña, Oscar S; León-Morales, Jesús de

    2017-01-01

    This paper addresses the design of attitude and airspeed controllers for a fixed wing unmanned aerial vehicle. An adaptive second order sliding mode control is proposed for improving performance under different operating conditions and is robust in presence of external disturbances. Moreover, this control does not require the knowledge of disturbance bounds and avoids overestimation of the control gains. Furthermore, in order to implement this controller, an extended observer is designed to estimate unmeasurable states as well as external disturbances. Additionally, sufficient conditions are given to guarantee the closed-loop stability of the observer based control. Finally, using a full 6 degree of freedom model, simulation results are obtained where the performance of the proposed method is compared against active disturbance rejection based on sliding mode control. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

  6. De novo centriole formation in human cells is error-prone and does not require SAS-6 self-assembly

    PubMed Central

    Wang, Won-Jing; Acehan, Devrim; Kao, Chien-Han; Jane, Wann-Neng; Uryu, Kunihiro; Tsou, Meng-Fu Bryan

    2015-01-01

    Vertebrate centrioles normally propagate through duplication, but in the absence of preexisting centrioles, de novo synthesis can occur. Consistently, centriole formation is thought to strictly rely on self-assembly, involving self-oligomerization of the centriolar protein SAS-6. Here, through reconstitution of de novo synthesis in human cells, we surprisingly found that normal looking centrioles capable of duplication and ciliation can arise in the absence of SAS-6 self-oligomerization. Moreover, whereas canonically duplicated centrioles always form correctly, de novo centrioles are prone to structural errors, even in the presence of SAS-6 self-oligomerization. These results indicate that centriole biogenesis does not strictly depend on SAS-6 self-assembly, and may require preexisting centrioles to ensure structural accuracy, fundamentally deviating from the current paradigm. DOI: http://dx.doi.org/10.7554/eLife.10586.001 PMID:26609813

  7. Automatic Censoring CFAR Detector Based on Ordered Data Difference for Low-Flying Helicopter Safety

    PubMed Central

    Jiang, Wen; Huang, Yulin; Yang, Jianyu

    2016-01-01

    Being equipped with a millimeter-wave radar allows a low-flying helicopter to sense the surroundings in real time, which significantly increases its safety. However, nonhomogeneous clutter environments, such as a multiple target situation and a clutter edge environment, can dramatically affect the radar signal detection performance. In order to improve the radar signal detection performance in nonhomogeneous clutter environments, this paper proposes a new automatic censored cell averaging CFAR detector. The proposed CFAR detector does not require any prior information about the background environment and uses the hypothesis test of the first-order difference (FOD) result of ordered data to reject the unwanted samples in the reference window. After censoring the unwanted ranked cells, the remaining samples are combined to form an estimate of the background power level, thus getting better radar signal detection performance. The simulation results show that the FOD-CFAR detector provides low loss CFAR performance in a homogeneous environment and also performs robustly in nonhomogeneous environments. Furthermore, the measured results of a low-flying helicopter validate the basic performance of the proposed method. PMID:27399714

  8. PP2B/calcineurin-mediated desensitization of TRPV1 does not require AKAP150

    PubMed Central

    Por, Elaine D.; Samelson, Bret K.; Belugin, Sergei; Akopian, Armen N.; Scott, John D.; Jeske, Nathaniel A.

    2011-01-01

    Activation of protein kinases and phosphatases at the plasma membrane often initiates agonist-dependent signalling events. In sensory neurons, AKAP150 (A-kinase-anchoring protein 150) orientates PKA (protein kinase A), PKC (protein kinase C) and the Ca2+/calmodulin-dependent PP2B (protein phosphatase 2B, also known as calcineurin) towards membrane-associated substrates. Recent evidence indicates that AKAP150-anchored PKA and PKC phosphorylate and sensitize the TRPV1 (transient receptor potential subfamily V type 1 channel, also known as the capsaicin receptor). In the present study, we explore the hypothesis that an AKAP150-associated pool of PP2B catalyses the dephosphorylation and desensitization of TRPV1. Biochemical, electrophysiological and cell-based experiments indicate that PP2B associates with AKAP150 and TRPV1 in cultured TG (trigeminal ganglia) neurons. Gene silencing of AKAP150 reduces basal phosphorylation of TRPV1. However, functional studies in neurons isolated from AKAP150−/− mice indicate that the anchoring protein is not required for pharmacological desensitization of TRPV1. Behavioural analysis of AKAP150−/− mice further support this notion, demonstrating that agonist-stimulated desensitization of TRPV1 is sensitive to PP2B inhibition and does not rely on AKAP150. These findings allow us to conclude that pharmacological desensitization of TRPV1 by PP2B may involve additional regulatory components. PMID:20883208

  9. PP2B/calcineurin-mediated desensitization of TRPV1 does not require AKAP150.

    PubMed

    Por, Elaine D; Samelson, Bret K; Belugin, Sergei; Akopian, Armen N; Scott, John D; Jeske, Nathaniel A

    2010-12-15

    Activation of protein kinases and phosphatases at the plasma membrane often initiates agonist-dependent signalling events. In sensory neurons, AKAP150 (A-kinase-anchoring protein 150) orientates PKA (protein kinase A), PKC (protein kinase C) and the Ca2+/calmodulin-dependent PP2B (protein phosphatase 2B, also known as calcineurin) towards membrane-associated substrates. Recent evidence indicates that AKAP150-anchored PKA and PKC phosphorylate and sensitize the TRPV1 (transient receptor potential subfamily V type 1 channel, also known as the capsaicin receptor). In the present study, we explore the hypothesis that an AKAP150-associated pool of PP2B catalyses the dephosphorylation and desensitization of TRPV1. Biochemical, electrophysiological and cell-based experiments indicate that PP2B associates with AKAP150 and TRPV1 in cultured TG (trigeminal ganglia) neurons. Gene silencing of AKAP150 reduces basal phosphorylation of TRPV1. However, functional studies in neurons isolated from AKAP150-/- mice indicate that the anchoring protein is not required for pharmacological desensitization of TRPV1. Behavioural analysis of AKAP150-/- mice further support this notion, demonstrating that agonist-stimulated desensitization of TRPV1 is sensitive to PP2B inhibition and does not rely on AKAP150. These findings allow us to conclude that pharmacological desensitization of TRPV1 by PP2B may involve additional regulatory components.

  10. DOE requests waiver on double containment for HLW canisters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lobsenz, G.

    1994-02-22

    The Energy Department has asked the Nuclear Regulatory Commission to waive double containment requirements for vitrified high-level radioactive waste canisters, saying the additional protection is not necessary and too costly. NRC said it had received a petition from DOE contending that the vitrified waste canisters were durable enough without double containment to prevent any potential plutonium release during handling and shipping. DOE said testing had shown that the vitrified waste canisters were similar - even superior - in durability to spent reactor fuel shipments, which NRC specifically exempted from the double containment requirement.

  11. 5 CFR 330.208 - Qualification requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... RECRUITMENT, SELECTION, AND PLACEMENT (GENERAL) Reemployment Priority List (RPL) § 330.208 Qualification... requirements for the position, including any minimum educational requirements, and any selection placement... alternative standard under the following conditions (this provision does not authorize waiver of the selection...

  12. The Lagrangian-Hamiltonian formalism for higher order field theories

    NASA Astrophysics Data System (ADS)

    Vitagliano, Luca

    2010-06-01

    We generalize the Lagrangian-Hamiltonian formalism of Skinner and Rusk to higher order field theories on fiber bundles. As a byproduct we solve the long standing problem of defining, in a coordinate free manner, a Hamiltonian formalism for higher order Lagrangian field theories. Namely, our formalism does only depend on the action functional and, therefore, unlike previously proposed ones, is free from any relevant ambiguity.

  13. Oxygen vacancy ordering in transition-metal-oxide LaCoO3 films

    NASA Astrophysics Data System (ADS)

    Biskup, Neven; Salafranca, Juan; Mehta, Virat; Suzuki, Yuri; Pennycook, Stephen; Pantelides, Sokrates; Varela, Maria

    2013-03-01

    Oxygen vacancies in complex oxides affect the structure and the electronic and magnetic properties. Here we use atomically-resolved Z-contrast imaging, electron-energy-loss spectroscopy and densityfunctional calculations to demonstrate that ordered oxygen vacancies may act as the controlling degree of freedom for the structural, electronic, and magnetic properties of LaCoO3 thin films. We find that epitaxial strain is released through the formation of O vacancy superlattices. The O vacancies donate excess electrons to the Co d-states, resulting in ferromagnetic ordering. The appearance of Peierls-like minigaps followed by strain relaxation triggers a nonlinear rupture of the energy bands, which explains the observed insulating behavior. We conclude that oxygen vacancy ordering constitutes a degree of freedom that can be used to engineer novel behavior in complex-oxide films. Research at ORNL supported by U.S. DOE-BES, Materials Sciences and Engineering Div. and by ORNL's ShaRE User Program (DOE-BES), at UCM by the ERC Starting Inv. Award, at UC Berkeley and LBNL by BES-DMSE, at Vanderbilt by U.S DOE and the McMinn Endowment.

  14. 14 CFR 1267.100 - What does this part do?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false What does this part do? 1267.100 Section... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 1267.100 What does this part... agreements and other financial assistance awards, as a matter of Federal Government policy. ...

  15. 14 CFR 1267.100 - What does this part do?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true What does this part do? 1267.100 Section... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 1267.100 What does this part... agreements and other financial assistance awards, as a matter of Federal Government policy. ...

  16. 29 CFR 1472.100 - What does this part do?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 4 2011-07-01 2011-07-01 false What does this part do? 1472.100 Section 1472.100 Labor... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 1472.100 What does this part... agreements and other financial assistance awards, as a matter of Federal Government policy. ...

  17. 29 CFR 1472.100 - What does this part do?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false What does this part do? 1472.100 Section 1472.100 Labor... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 1472.100 What does this part... agreements and other financial assistance awards, as a matter of Federal Government policy. ...

  18. 22 CFR 133.100 - What does this part do?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false What does this part do? 133.100 Section 133.100 Foreign Relations DEPARTMENT OF STATE MISCELLANEOUS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 133.100 What does this part do? This part carries out the...

  19. 14 CFR 382.27 - May a carrier require a passenger with a disability to provide advance notice in order to obtain...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... service animal in the cabin; (9) Transportation of a service animal on a flight segment scheduled to take... disability to provide advance notice in order to obtain certain specific services in connection with a flight... Nondiscrimination and Access to Services and Information § 382.27 May a carrier require a passenger with a...

  20. 14 CFR 382.27 - May a carrier require a passenger with a disability to provide advance notice in order to obtain...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... service animal in the cabin; (9) Transportation of a service animal on a flight segment scheduled to take... disability to provide advance notice in order to obtain certain specific services in connection with a flight... Nondiscrimination and Access to Services and Information § 382.27 May a carrier require a passenger with a...

  1. Aldosterone does not require angiotensin II to activate NCC through a WNK4-SPAK-dependent pathway.

    PubMed

    van der Lubbe, Nils; Lim, Christina H; Meima, Marcel E; van Veghel, Richard; Rosenbaek, Lena Lindtoft; Mutig, Kerim; Danser, Alexander H J; Fenton, Robert A; Zietse, Robert; Hoorn, Ewout J

    2012-06-01

    We and others have recently shown that angiotensin II can activate the sodium chloride cotransporter (NCC) through a WNK4-SPAK-dependent pathway. Because WNK4 was previously shown to be a negative regulator of NCC, it has been postulated that angiotensin II converts WNK4 to a positive regulator. Here, we ask whether aldosterone requires angiotensin II to activate NCC and if their effects are additive. To do so, we infused vehicle or aldosterone in adrenalectomized rats that also received the angiotensin receptor blocker losartan. In the presence of losartan, aldosterone was still capable of increasing total and phosphorylated NCC twofold to threefold. The kinases WNK4 and SPAK also increased with aldosterone and losartan. A dose-dependent relationship between aldosterone and NCC, SPAK, and WNK4 was identified, suggesting that these are aldosterone-sensitive proteins. As more functional evidence of increased NCC activity, we showed that rats receiving aldosterone and losartan had a significantly greater natriuretic response to hydrochlorothiazide than rats receiving losartan only. To study whether angiotensin II could have an additive effect, rats receiving aldosterone with losartan were compared with rats receiving aldosterone only. Rats receiving aldosterone only retained more sodium and had twofold to fourfold increase in phosphorylated NCC. Together, our results demonstrate that aldosterone does not require angiotensin II to activate NCC and that WNK4 appears to act as a positive regulator in this pathway. The additive effect of angiotensin II may favor electroneutral sodium reabsorption during hypovolemia and may contribute to hypertension in diseases with an activated renin-angiotensin-aldosterone system.

  2. Sustainable institutionalized punishment requires elimination of second-order free-riders

    NASA Astrophysics Data System (ADS)

    Perc, Matjaž

    2012-03-01

    Although empirical and theoretical studies affirm that punishment can elevate collaborative efforts, its emergence and stability remain elusive. By peer-punishment the sanctioning is something an individual elects to do depending on the strategies in its neighborhood. The consequences of unsustainable efforts are therefore local. By pool-punishment, on the other hand, where resources for sanctioning are committed in advance and at large, the notion of sustainability has greater significance. In a population with free-riders, punishers must be strong in numbers to keep the ``punishment pool'' from emptying. Failure to do so renders the concept of institutionalized sanctioning futile. We show that pool-punishment in structured populations is sustainable, but only if second-order free-riders are sanctioned as well, and to a such degree that they cannot prevail. A discontinuous phase transition leads to an outbreak of sustainability when punishers subvert second-order free-riders in the competition against defectors.

  3. 31 CFR 20.100 - What does this part do?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false What does this part do? 20.100 Section 20.100 Money and Finance: Treasury Office of the Secretary of the Treasury GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 20.100 What does this part...

  4. 31 CFR 20.100 - What does this part do?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false What does this part do? 20.100 Section 20.100 Money and Finance: Treasury Office of the Secretary of the Treasury GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 20.100 What does this part...

  5. 31 CFR 20.100 - What does this part do?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false What does this part do? 20.100 Section 20.100 Money and Finance: Treasury Office of the Secretary of the Treasury GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 20.100 What does this part...

  6. 31 CFR 20.100 - What does this part do?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false What does this part do? 20.100 Section 20.100 Money and Finance: Treasury Office of the Secretary of the Treasury GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 20.100 What does this part...

  7. 31 CFR 20.100 - What does this part do?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false What does this part do? 20.100 Section 20.100 Money and Finance: Treasury Office of the Secretary of the Treasury GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 20.100 What does this part...

  8. 75 FR 38587 - Self-Regulatory Organizations; International Securities Exchange, LLC; Order Approving Proposed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... Order Feed, which provides real-time updates every time a new limit order that is not immediately... each instrument series, including the symbols (series and underlying security), put or call indicator, the expiration and the strike price of the series. \\4\\ The ISE Order Feed does not include market...

  9. 21 CFR 820.180 - General requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... DEVICES QUALITY SYSTEM REGULATION Records § 820.180 General requirements. All records required by this... retained for a period of time equivalent to the design and expected life of the device, but in no case less.... This section does not apply to the reports required by § 820.20(c) Management review, § 820.22 Quality...

  10. 21 CFR 820.180 - General requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... DEVICES QUALITY SYSTEM REGULATION Records § 820.180 General requirements. All records required by this... retained for a period of time equivalent to the design and expected life of the device, but in no case less.... This section does not apply to the reports required by § 820.20(c) Management review, § 820.22 Quality...

  11. 21 CFR 820.180 - General requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... DEVICES QUALITY SYSTEM REGULATION Records § 820.180 General requirements. All records required by this... retained for a period of time equivalent to the design and expected life of the device, but in no case less.... This section does not apply to the reports required by § 820.20(c) Management review, § 820.22 Quality...

  12. 21 CFR 820.180 - General requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... DEVICES QUALITY SYSTEM REGULATION Records § 820.180 General requirements. All records required by this... retained for a period of time equivalent to the design and expected life of the device, but in no case less.... This section does not apply to the reports required by § 820.20(c) Management review, § 820.22 Quality...

  13. 21 CFR 820.180 - General requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... DEVICES QUALITY SYSTEM REGULATION Records § 820.180 General requirements. All records required by this... retained for a period of time equivalent to the design and expected life of the device, but in no case less.... This section does not apply to the reports required by § 820.20(c) Management review, § 820.22 Quality...

  14. A STATISTICAL THERMODYNAMIC MODEL OF THE ORGANIZATIONAL ORDER OF VEGETATION. (R827676)

    EPA Science Inventory

    The complex pattern of vegetation is the macroscopic manifestation of biological diversity and the ecological order in space and time. How is this overwhelmingly diverse, yet wonderfully ordered spatial pattern formed, and how does it evolve? To answer these questions, most tr...

  15. Evolution of US DOE Performance Assessments Over 20 Years - 13597

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Suttora, Linda C.; Seitz, Roger R.

    2013-07-01

    Performance assessments (PAs) have been used for many years for the analysis of post-closure hazards associated with a radioactive waste disposal facility and to provide a reasonable expectation of the ability of the site and facility design to meet objectives for the protection of members of the public and the environment. The use of PA to support decision-making for LLW disposal facilities has been mandated in United States Department of Energy (US DOE) directives governing radioactive waste management since 1988 (currently DOE Order 435.1, Radioactive Waste Management). Prior to that time, PAs were also used in a less formal role.more » Over the past 20+ years, the US DOE approach to conduct, review and apply PAs has evolved into an efficient, rigorous and mature process that includes specific requirements for continuous improvement and independent reviews. The PA process has evolved through refinement of a graded and iterative approach designed to help focus efforts on those aspects of the problem expected to have the greatest influence on the decision being made. Many of the evolutionary changes to the PA process are linked to the refinement of the PA maintenance concept that has proven to be an important element of US DOE PA requirements in the context of supporting decision-making for safe disposal of LLW. The PA maintenance concept is central to the evolution of the graded and iterative philosophy and has helped to drive the evolution of PAs from a deterministic compliance calculation into a systematic approach that helps to focus on critical aspects of the disposal system in a manner designed to provide a more informed basis for decision-making throughout the life of a disposal facility (e.g., monitoring, research and testing, waste acceptance criteria, design improvements, data collection, model refinements). A significant evolution in PA modeling has been associated with improved use of uncertainty and sensitivity analysis techniques to support

  16. Discovering local order parameters in liquid water using machine learning

    NASA Astrophysics Data System (ADS)

    Soto, Adrian; Lu, Deyu; Yoo, Shinjae; Fernandez-Serra, Marivi

    The local arrangement of water molecules in liquid phase is still being discussed and questioned. The prevailing view is that water is composed of a mixture of two structurally different liquids. One of the main challenges has been to find order parameters that are able to discriminate the complex structures of these distinct molecular environments. Several local order parameters have been proposed and studied in all sorts of atomistic simulations of liquid water but, to date, none has been able to capture the predicted dual character. This presents an ideal problem to treat with methods capable of unveiling information from complex data. In this talk we will discuss how local order parameters can be constructed from molecular dynamics trajectories by using machine learning and other related techniques. Work was partially supported by DOE Award No. DE-FG02-09ER16052, by DOE Early Career Award No. DE-SC0003871, by BNL LDRD 16-039 project and BNL Contract No. DE-SC0012704.

  17. Adaptive h -refinement for reduced-order models: ADAPTIVE h -refinement for reduced-order models

    DOE PAGES

    Carlberg, Kevin T.

    2014-11-05

    Our work presents a method to adaptively refine reduced-order models a posteriori without requiring additional full-order-model solves. The technique is analogous to mesh-adaptive h-refinement: it enriches the reduced-basis space online by ‘splitting’ a given basis vector into several vectors with disjoint support. The splitting scheme is defined by a tree structure constructed offline via recursive k-means clustering of the state variables using snapshot data. This method identifies the vectors to split online using a dual-weighted-residual approach that aims to reduce error in an output quantity of interest. The resulting method generates a hierarchy of subspaces online without requiring large-scale operationsmore » or full-order-model solves. Furthermore, it enables the reduced-order model to satisfy any prescribed error tolerance regardless of its original fidelity, as a completely refined reduced-order model is mathematically equivalent to the original full-order model. Experiments on a parameterized inviscid Burgers equation highlight the ability of the method to capture phenomena (e.g., moving shocks) not contained in the span of the original reduced basis.« less

  18. Where Does the Ordered Line Come From? Evidence From a Culture of Papua New Guinea.

    PubMed

    Cooperrider, Kensy; Marghetis, Tyler; Núñez, Rafael

    2017-05-01

    Number lines, calendars, and measuring sticks all represent order along some dimension (e.g., magnitude) as position on a line. In high-literacy, industrialized societies, this principle of spatial organization- linear order-is a fixture of visual culture and everyday cognition. But what are the principle's origins, and how did it become such a fixture? Three studies investigated intuitions about linear order in the Yupno, members of a culture of Papua New Guinea that lacks conventional representations involving ordered lines, and in U.S. undergraduates. Presented with cards representing differing sizes and numerosities, both groups arranged them using linear order or sometimes spatial grouping, a competing principle. But whereas the U.S. participants produced ordered lines in all tasks, strongly favoring a left-to-right format, the Yupno produced them less consistently, and with variable orientations. Conventional linear representations are thus not necessary to spark the intuition of linear order-which may have other experiential sources-but they nonetheless regiment when and how the principle is used.

  19. 14 CFR 382.27 - May a carrier require a passenger with a disability to provide advance notice in order to obtain...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false May a carrier require a passenger with a disability to provide advance notice in order to obtain certain specific services in connection with a flight? 382.27 Section 382.27 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) SPECIAL REGULATIONS...

  20. 10 CFR 1021.300 - General requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false General requirements. 1021.300 Section 1021.300 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NATIONAL ENVIRONMENTAL POLICY ACT IMPLEMENTING PROCEDURES Implementing Procedures § 1021.300 General requirements. (a) DOE shall determine, under the procedures in the...

  1. 48 CFR 11.101 - Order of precedence for requirements documents.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Order of precedence for... A-119, “Federal Participation in the Development and Use of Voluntary Consensus Standards and in... of 1995, Pub. L. 104-113 (15 U.S.C. 272 note), agencies must use voluntary consensus standards, when...

  2. 40 CFR 90.503 - Test orders.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Test orders. 90.503 Section 90.503....503 Test orders. (a) The Administrator shall require any testing under this subpart by means of a test order addressed to the manufacturer. (b) The test order will be signed by the Assistant Administrator...

  3. An analytical chemistry laboratory's experiences under Department of Energy Order 5633. 3 - a status report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bingham, C.D.

    The U.S. Department of Energy (DOE) order 5633.3, Control and Accountability of Nuclear Materials, initiated substantial changes to the requirements for operations involving nuclear materials. In the opinion of this author, the two most significant changes are the clarification of and the increased emphasis on the concept of graded safeguards and the implementation of performance requirements. Graded safeguards recognizes that some materials are more attractive than others to potential adversary actions and, thus, should be afforded a higher level of integrated safeguards effort. An analytical chemistry laboratory, such as the New Brunswick Laboratory (NBL), typically has a small total inventorymore » of special nuclear materials compared to, for example, a production or manufacturing facility. The NBL has a laboratory information management system (LIMS) that not only provides the sample identification and tracking but also incorporates the essential features of MC A required of NBL operations. As a consequence of order 5633.3, NBL had to modify LIMS to accommodate material attractiveness information for the logging process, to reflect changes in the attractiveness as the material was processed through the laboratory, and to enable inventory information to be accumulated by material attractiveness as the material was processed through the laboratory, and to enable inventory information to be accumulated by material attractiveness codes.« less

  4. 2 CFR 182.5 - What does this part do?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false What does this part do? 182.5 Section 182.5... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) § 182.5 What does this part do? This part provides... of the Act to cooperative agreements and other financial assistance awards, as a matter of Federal...

  5. Character order processing in Chinese reading.

    PubMed

    Gu, Junjuan; Li, Xingshan; Liversedge, Simon P

    2015-02-01

    We explored how character order information is encoded in isolated word processing or Chinese sentence reading in 2 experiments using a masked priming paradigm and a gaze-contingent display-change paradigm. The results showed that response latencies in the lexical decision task and reading times on the target word region were longer in the unrelated condition (the prime or the preview was unrelated with the target word) than the transposed-character condition (the prime or the preview was a transposition of the 2 characters of the target word), which were respectively longer than in the identity condition (the prime or preview was identical to the target word). These results show that character order is encoded at an early stage of processing in Chinese reading, but character position encoding was not strict. We also found that character order encoding was similar for single-morpheme and multiple-morpheme words, suggesting that morphemic status does not affect character order encoding. The current results represent an early contribution to our understanding of character order encoding during Chinese reading.

  6. Pre-registration house officer rotations incorporating general practice: does the order of rotation matter?

    PubMed

    Williams, C; Cantillon, P; Cochrane, M

    2001-06-01

    In relation to pre-registration house officer (PRHO) rotations incorporating general practice, previous research has recommended that where possible, no PRHO should undertake general practice as the first placement, because of the difficulties encountered. It was recognized that logistically, this could make such schemes almost unworkable. Within the context of a larger qualitative evaluation comparing how 24 PRHOs learned in hospital and general practice settings, the issue of rotation order was explored. In-depth semistructured interviews were conducted with the 12 PRHOs who were involved in general practice rotations. They were interviewed at the beginning and end of the PRHO year, and following their return to hospital work after the general practice placement. Each rotation order had both advantages and disadvantages, with no particular rotation order being obviously better or worse for the PRHOs involved. This small qualitative evaluation has highlighted a number of advantages and disadvantages specific to each rotation order, and makes some practical recommendations to help alleviate the problems encountered. It is important that future evaluations of similar schemes consider this issue, as there are conflicting reports about the significance of the rotation order.

  7. 48 CFR 411.101 - Order of precedence for requirements documents.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... AGRICULTURE COMPETITION AND ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Selecting and Developing Requirements... National Institute of Standards and Technology in accordance with the Circular with a copy provided to the...

  8. 24 CFR 761.21 - Plan requirement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... funding source for each activity, identifying in particular all activities to be funded under this part... requirement. (a) General requirement. To receive funding under this part, each PHDEP qualified recipient or... the application for PHDEP funding, and an otherwise qualified recipient that does not submit a PHDEP...

  9. 40 CFR 89.503 - Test orders.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Test orders. 89.503 Section 89.503... Test orders. (a) A test order addressed to the manufacturer is required for any testing under this subpart. (b) The test order is signed by the Assistant Administrator for Air and Radiation or his or her...

  10. 10 CFR 218.11 - Supply orders.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Supply orders. 218.11 Section 218.11 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION Supply Orders § 218.11 Supply orders. (a) A supply order shall require that the firm to which it is issued take actions specified therein relating to...

  11. Cognitive Effort Requirements in Recall, Recognition, and Lexical Decision

    DTIC Science & Technology

    1985-05-01

    that the amount of integrative processing required for an item is a function of its preexisting or baseline familiarity level . Low frequency words... Lockhart , Craik , & Jacoby, 1976). In the present study, increased effort, and possibly increased distinctiveness, does not influence hit rates, which are...ing of items. Second, a lexical decision task, which does not require elabo- rative processing , leads to an overall poor level of recall. Furthermore

  12. Quantifying and Addressing the DOE Material Reactivity Requirements with Analysis and Testing of Hydrogen Storage Materials & Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Khalil, Y. F.

    2012-04-30

    The objective of this project is to examine safety aspects of candidate hydrogen storage materials and systems being developed in the DOE Hydrogen Program. As a result of this effort, the general DOE safety target will be given useful meaning by establishing a link between the characteristics of new storage materials and the satisfaction of safety criteria. This will be accomplished through the development and application of formal risk analysis methods, standardized materials testing, chemical reactivity characterization, novel risk mitigation approaches and subscale system demonstration. The project also will collaborate with other DOE and international activities in materials based hydrogenmore » storage safety to provide a larger, highly coordinated effort.« less

  13. Efficient Reformulation of the Thermoelastic Higher-order Theory for Fgms

    NASA Technical Reports Server (NTRS)

    Bansal, Yogesh; Pindera, Marek-Jerzy; Arnold, Steven M. (Technical Monitor)

    2002-01-01

    Functionally graded materials (FGMs) are characterized by spatially variable microstructures which are introduced to satisfy given performance requirements. The microstructural gradation gives rise to continuously or discretely changing material properties which complicate FGM analysis. Various techniques have been developed during the past several decades for analyzing traditional composites and many of these have been adapted for the analysis of FGMs. Most of the available techniques use the so-called uncoupled approach in order to analyze graded structures. These techniques ignore the effect of microstructural gradation by employing specific spatial material property variations that are either assumed or obtained by local homogenization. The higher-order theory for functionally graded materials (HOTFGM) is a coupled approach developed by Aboudi et al. (1999) which takes the effect of microstructural gradation into consideration and does not ignore the local-global interaction of the spatially variable inclusion phase(s). Despite its demonstrated utility, however, the original formulation of the higher-order theory is computationally intensive. Herein, an efficient reformulation of the original higher-order theory for two-dimensional elastic problems is developed and validated. The use of the local-global conductivity and local-global stiffness matrix approach is made in order to reduce the number of equations involved. In this approach, surface-averaged quantities are the primary variables which replace volume-averaged quantities employed in the original formulation. The reformulation decreases the size of the global conductivity and stiffness matrices by approximately sixty percent. Various thermal, mechanical, and combined thermomechanical problems are analyzed in order to validate the accuracy of the reformulated theory through comparison with analytical and finite-element solutions. The presented results illustrate the efficiency of the reformulation and its

  14. Higher-order awareness, misrepresentation and function

    PubMed Central

    Rosenthal, David

    2012-01-01

    Conscious mental states are states we are in some way aware of. I compare higher-order theories of consciousness, which explain consciousness by appeal to such higher-order awareness (HOA), and first-order theories, which do not, and I argue that higher-order theories have substantial explanatory advantages. The higher-order nature of our awareness of our conscious states suggests an analogy with the metacognition that figures in the regulation of psychological processes and behaviour. I argue that, although both consciousness and metacognition involve higher-order psychological states, they have little more in common. One thing they do share is the possibility of misrepresentation; just as metacognitive processing can misrepresent one's cognitive states and abilities, so the HOA in virtue of which one's mental states are conscious can, and sometimes does, misdescribe those states. A striking difference between the two, however, has to do with utility for psychological processing. Metacognition has considerable benefit for psychological processing; in contrast, it is unlikely that there is much, if any, utility to mental states' being conscious over and above the utility those states have when they are not conscious. PMID:22492758

  15. Determining Reduced Order Models for Optimal Stochastic Reduced Order Models

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bonney, Matthew S.; Brake, Matthew R.W.

    2015-08-01

    The use of parameterized reduced order models(PROMs) within the stochastic reduced order model (SROM) framework is a logical progression for both methods. In this report, five different parameterized reduced order models are selected and critiqued against the other models along with truth model for the example of the Brake-Reuss beam. The models are: a Taylor series using finite difference, a proper orthogonal decomposition of the the output, a Craig-Bampton representation of the model, a method that uses Hyper-Dual numbers to determine the sensitivities, and a Meta-Model method that uses the Hyper-Dual results and constructs a polynomial curve to better representmore » the output data. The methods are compared against a parameter sweep and a distribution propagation where the first four statistical moments are used as a comparison. Each method produces very accurate results with the Craig-Bampton reduction having the least accurate results. The models are also compared based on time requirements for the evaluation of each model where the Meta- Model requires the least amount of time for computation by a significant amount. Each of the five models provided accurate results in a reasonable time frame. The determination of which model to use is dependent on the availability of the high-fidelity model and how many evaluations can be performed. Analysis of the output distribution is examined by using a large Monte-Carlo simulation along with a reduced simulation using Latin Hypercube and the stochastic reduced order model sampling technique. Both techniques produced accurate results. The stochastic reduced order modeling technique produced less error when compared to an exhaustive sampling for the majority of methods.« less

  16. 10 CFR 60.3 - License required.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false License required. 60.3 Section 60.3 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.3 License required. (a) DOE shall not receive or possess source, special nuclear, or...

  17. 10 CFR 60.3 - License required.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false License required. 60.3 Section 60.3 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.3 License required. (a) DOE shall not receive or possess source, special nuclear, or...

  18. 10 CFR 60.3 - License required.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false License required. 60.3 Section 60.3 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.3 License required. (a) DOE shall not receive or possess source, special nuclear, or...

  19. A reverse order interview does not aid deception detection regarding intentions

    PubMed Central

    Fenn, Elise; McGuire, Mollie; Langben, Sara; Blandón-Gitlin, Iris

    2015-01-01

    Promising recent research suggests that more cognitively demanding interviews improve deception detection accuracy. Would these cognitively demanding techniques work in the same way when discriminating between true and false future intentions? In Experiment 1 participants planned to complete a task, but instead were intercepted and interviewed about their intentions. Participants lied or told the truth, and were subjected to high (reverse order) or low (sequential order) cognitive load interviews. Third-party observers watched these interviews and indicated whether they thought the person was lying or telling the truth. Subjecting participants to a reverse compared to sequential interview increased the misidentification rate and the appearance of cognitive load in truth tellers. People lying about false intentions were not better identified. In Experiment 2, a second set of third-party observers rated behavioral cues. Consistent with Experiment 1, truth tellers, but not liars, exhibited more behaviors associated with lying and fewer behaviors associated with truth telling in the reverse than sequential interview. Together these results suggest that certain cognitively demanding interviews may be less useful when interviewing to detect false intentions. Explaining a true intention while under higher cognitive demand places truth tellers at risk of being misclassified. There may be such a thing as too much cognitive load induced by certain techniques PMID:26379610

  20. A reverse order interview does not aid deception detection regarding intentions.

    PubMed

    Fenn, Elise; McGuire, Mollie; Langben, Sara; Blandón-Gitlin, Iris

    2015-01-01

    Promising recent research suggests that more cognitively demanding interviews improve deception detection accuracy. Would these cognitively demanding techniques work in the same way when discriminating between true and false future intentions? In Experiment 1 participants planned to complete a task, but instead were intercepted and interviewed about their intentions. Participants lied or told the truth, and were subjected to high (reverse order) or low (sequential order) cognitive load interviews. Third-party observers watched these interviews and indicated whether they thought the person was lying or telling the truth. Subjecting participants to a reverse compared to sequential interview increased the misidentification rate and the appearance of cognitive load in truth tellers. People lying about false intentions were not better identified. In Experiment 2, a second set of third-party observers rated behavioral cues. Consistent with Experiment 1, truth tellers, but not liars, exhibited more behaviors associated with lying and fewer behaviors associated with truth telling in the reverse than sequential interview. Together these results suggest that certain cognitively demanding interviews may be less useful when interviewing to detect false intentions. Explaining a true intention while under higher cognitive demand places truth tellers at risk of being misclassified. There may be such a thing as too much cognitive load induced by certain techniques.

  1. 22 CFR 133.105 - Does this part apply to me?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Does this part apply to me? 133.105 Section 133.105 Foreign Relations DEPARTMENT OF STATE MISCELLANEOUS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 133.105 Does this part apply to me? (a) Portions of...

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    Code of Federal Regulations, 2011 CFR

    2011-07-01

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    Code of Federal Regulations, 2012 CFR

    2012-01-01

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    Code of Federal Regulations, 2013 CFR

    2013-01-01

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    Code of Federal Regulations, 2010 CFR

    2010-07-01

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  6. 13 CFR 147.105 - Does this part apply to me?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

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    Code of Federal Regulations, 2011 CFR

    2011-04-01

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    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Does this part apply to me? 210.105 Section 210.105 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 210.105 Does this part apply to me? (a) Portions of...

  9. 22 CFR 1008.105 - Does this part apply to me?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Does this part apply to me? 1008.105 Section 1008.105 Foreign Relations INTER-AMERICAN FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 1008.105 Does this part apply to me? (a) Portions of...

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    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Does this part apply to me? 83.105 Section 83.105 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GOVERNMENT-WIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Purpose and Coverage § 83.105 Does this part apply to me? (a) Portions of...

  11. 22 CFR 133.105 - Does this part apply to me?

    Code of Federal Regulations, 2010 CFR

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    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Does this part apply to me? 133.105 Section 133.105 Foreign Relations DEPARTMENT OF STATE MISCELLANEOUS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 133.105 Does this part apply to me? (a) Portions of...

  12. 13 CFR 147.105 - Does this part apply to me?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Does this part apply to me? 147.105 Section 147.105 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (NONPROCUREMENT) Purpose and Coverage § 147.105 Does this part apply to me...

  13. 22 CFR 133.105 - Does this part apply to me?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Does this part apply to me? 133.105 Section 133.105 Foreign Relations DEPARTMENT OF STATE MISCELLANEOUS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 133.105 Does this part apply to me? (a) Portions of...

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    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Does this part apply to me? 83.105 Section 83.105 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GOVERNMENT-WIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Purpose and Coverage § 83.105 Does this part apply to me? (a) Portions of...

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    Code of Federal Regulations, 2010 CFR

    2010-04-01

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    Code of Federal Regulations, 2013 CFR

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    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Does this part apply to me? 1509.105 Section 1509.105 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 1509.105 Does this part apply to me? (a) Portions of...

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    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Does this part apply to me? 210.105 Section 210.105 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 210.105 Does this part apply to me? (a) Portions of...

  18. 22 CFR 1509.105 - Does this part apply to me?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Does this part apply to me? 1509.105 Section 1509.105 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 1509.105 Does this part apply to me? (a) Portions of...

  19. 22 CFR 133.105 - Does this part apply to me?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Does this part apply to me? 133.105 Section 133.105 Foreign Relations DEPARTMENT OF STATE MISCELLANEOUS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage § 133.105 Does this part apply to me? (a) Portions of...

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