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Sample records for reviewing procedure pri

  1. 36 CFR 908.32 - Review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Review procedures. 908.32... DEVELOPMENT AREA Review Procedure § 908.32 Review procedures. (a) Upon receipt of a request for review, the... applicable regulations; (2) Information submitted by the applicant including the request for review and...

  2. 36 CFR 908.32 - Review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false Review procedures. 908.32... DEVELOPMENT AREA Review Procedure § 908.32 Review procedures. (a) Upon receipt of a request for review, the... applicable regulations; (2) Information submitted by the applicant including the request for review and...

  3. Procedures for Peer Review of Grant Applications

    ERIC Educational Resources Information Center

    US Department of Education, 2006

    2006-01-01

    This guide presents information on the procedures for peer review of grant applications. It begins with an overview of the review process for grant application submission and review. The review process includes: (1) pre-submission procedures that enable the Institute to plan for specific review sessions; (2) application processing procedures; (3)…

  4. 19 CFR 351.221 - Review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 3 2011-04-01 2011-04-01 false Review procedures. 351.221 Section 351.221 Customs... Antidumping and Countervailing Duty Procedures § 351.221 Review procedures. (a) Introduction. The procedures for reviews are similar to those followed in investigations. This section details the...

  5. 49 CFR 601.47 - Review Procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 7 2011-10-01 2011-10-01 false Review Procedures. 601.47 Section 601.47 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ORGANIZATION, FUNCTIONS, AND PROCEDURES Emergency Procedures for Public Transportation Systems § 601.47 Review Procedures....

  6. 12 CFR 1408.10 - Review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 9 2012-01-01 2012-01-01 false Review procedures. 1408.10 Section 1408.10... Administrative Collection of Claims § 1408.10 Review procedures. (a) Unless an oral hearing is required by § 1408.23(d), the Corporation's review shall be a review of the written record of the claim. (b) If an...

  7. 12 CFR 608.810 - Review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Review procedures. 608.810 Section 608.810... UNITED STATES Administrative Collection of Claims § 608.810 Review procedures. (a) Unless an oral hearing is required by § 608.823(d), the FCA's review shall be a review of the written record of the...

  8. 42 CFR 431.812 - Review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Review procedures. 431.812 Section 431.812 Public... Eligibility Quality Control (meqc) Program § 431.812 Review procedures. (a) Active case reviews. (1) Except as provided in paragraph (a)(2) of this section, the agency must review all active cases selected from...

  9. 16 CFR 260.4 - Review procedure.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 1 2012-01-01 2012-01-01 false Review procedure. 260.4 Section 260.4... ENVIRONMENTAL MARKETING CLAIMS § 260.4 Review procedure. The Commission will review the guides as part of its... of a claim or regarding substantiation of a claim. Following review of such a petition,...

  10. 12 CFR 608.810 - Review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 7 2013-01-01 2013-01-01 false Review procedures. 608.810 Section 608.810... UNITED STATES Administrative Collection of Claims § 608.810 Review procedures. (a) Unless an oral hearing is required by § 608.823(d), the FCA's review shall be a review of the written record of the...

  11. 12 CFR 1408.10 - Review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Review procedures. 1408.10 Section 1408.10... Administrative Collection of Claims § 1408.10 Review procedures. (a) Unless an oral hearing is required by § 1408.23(d), the Corporation's review shall be a review of the written record of the claim. (b) If an...

  12. 12 CFR 1408.10 - Review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 9 2013-01-01 2013-01-01 false Review procedures. 1408.10 Section 1408.10... Administrative Collection of Claims § 1408.10 Review procedures. (a) Unless an oral hearing is required by § 1408.23(d), the Corporation's review shall be a review of the written record of the claim. (b) If an...

  13. 12 CFR 1408.10 - Review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Review procedures. 1408.10 Section 1408.10... Administrative Collection of Claims § 1408.10 Review procedures. (a) Unless an oral hearing is required by § 1408.23(d), the Corporation's review shall be a review of the written record of the claim. (b) If an...

  14. 12 CFR 608.810 - Review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 7 2014-01-01 2014-01-01 false Review procedures. 608.810 Section 608.810... UNITED STATES Administrative Collection of Claims § 608.810 Review procedures. (a) Unless an oral hearing is required by § 608.823(d), the FCA's review shall be a review of the written record of the...

  15. 39 CFR 776.9 - Review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Review procedures. 776.9 Section 776.9 Postal Service UNITED STATES POSTAL SERVICE ENVIRONMENTAL REGULATIONS FLOODPLAIN AND WETLAND PROCEDURES Wetlands Protection § 776.9 Review procedures. (a) Early public notice. If a facility action at the contending...

  16. 39 CFR 776.9 - Review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 39 Postal Service 1 2013-07-01 2013-07-01 false Review procedures. 776.9 Section 776.9 Postal Service UNITED STATES POSTAL SERVICE ENVIRONMENTAL REGULATIONS FLOODPLAIN AND WETLAND PROCEDURES Wetlands Protection § 776.9 Review procedures. (a) Early public notice. If a facility action at the contending...

  17. 39 CFR 776.9 - Review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Review procedures. 776.9 Section 776.9 Postal Service UNITED STATES POSTAL SERVICE ENVIRONMENTAL REGULATIONS FLOODPLAIN AND WETLAND PROCEDURES Wetlands Protection § 776.9 Review procedures. (a) Early public notice. If a facility action at the contending...

  18. 39 CFR 776.9 - Review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Review procedures. 776.9 Section 776.9 Postal Service UNITED STATES POSTAL SERVICE ENVIRONMENTAL REGULATIONS FLOODPLAIN AND WETLAND PROCEDURES Wetlands Protection § 776.9 Review procedures. (a) Early public notice. If a facility action at the contending...

  19. 39 CFR 776.9 - Review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 39 Postal Service 1 2014-07-01 2014-07-01 false Review procedures. 776.9 Section 776.9 Postal Service UNITED STATES POSTAL SERVICE ENVIRONMENTAL REGULATIONS FLOODPLAIN AND WETLAND PROCEDURES Wetlands Protection § 776.9 Review procedures. (a) Early public notice. If a facility action at the contending...

  20. 50 CFR 13.29 - Review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 1 2014-10-01 2014-10-01 false Review procedures. 13.29 Section 13.29... GENERAL PERMIT PROCEDURES Permit Administration § 13.29 Review procedures. (a) Request for reconsideration... the matter under consideration. (d) Determination of grant or denial of a request for...

  1. 12 CFR 797.9 - Review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 7 2012-01-01 2012-01-01 false Review procedures. 797.9 Section 797.9 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING THE OPERATIONS OF THE NATIONAL CREDIT UNION ADMINISTRATION PROCEDURES FOR DEBT COLLECTION Administrative Offset § 797.9 Review procedures. (a) Unless an oral hearing is required...

  2. 50 CFR 13.29 - Review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 1 2012-10-01 2012-10-01 false Review procedures. 13.29 Section 13.29... GENERAL PERMIT PROCEDURES Permit Administration § 13.29 Review procedures. (a) Request for reconsideration... the matter under consideration. (d) Determination of grant or denial of a request for...

  3. 50 CFR 13.29 - Review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 1 2013-10-01 2013-10-01 false Review procedures. 13.29 Section 13.29... GENERAL PERMIT PROCEDURES Permit Administration § 13.29 Review procedures. (a) Request for reconsideration... the matter under consideration. (d) Determination of grant or denial of a request for...

  4. 12 CFR 797.9 - Review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Review procedures. 797.9 Section 797.9 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING THE OPERATIONS OF THE NATIONAL CREDIT UNION ADMINISTRATION PROCEDURES FOR DEBT COLLECTION Administrative Offset § 797.9 Review procedures. (a) Unless an oral hearing is required...

  5. 50 CFR 13.29 - Review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 1 2011-10-01 2011-10-01 false Review procedures. 13.29 Section 13.29... GENERAL PERMIT PROCEDURES Permit Administration § 13.29 Review procedures. (a) Request for reconsideration... the matter under consideration. (d) Determination of grant or denial of a request for...

  6. 50 CFR 13.29 - Review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Review procedures. 13.29 Section 13.29... GENERAL PERMIT PROCEDURES Permit Administration § 13.29 Review procedures. (a) Request for reconsideration... the matter under consideration. (d) Determination of grant or denial of a request for...

  7. 49 CFR 802.14 - Review procedure and judicial review.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Review procedure and judicial review. 802.14 Section 802.14 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL TRANSPORTATION SAFETY BOARD RULES IMPLEMENTING THE PRIVACY ACT OF 1974 Review of Initial Adverse Determination § 802.14 Review procedure and judicial review....

  8. 49 CFR 211.47 - Review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Review procedures. 211.47 Section 211.47..., DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE Emergency Orders § 211.47 Review procedures. (a) As specified in section 203, Public Law 91-458, 84 Stat. 972 (45 U.S.C. 432), opportunity for review of...

  9. 49 CFR 211.47 - Review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Review procedures. 211.47 Section 211.47..., DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE Emergency Orders § 211.47 Review procedures. (a) As specified in section 203, Public Law 91-458, 84 Stat. 972 (45 U.S.C. 432), opportunity for review of...

  10. 40 CFR 142.80 - Review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 23 2011-07-01 2011-07-01 false Review procedures. 142.80 Section 142...) NATIONAL PRIMARY DRINKING WATER REGULATIONS IMPLEMENTATION Administrator's Review of State Decisions that Implement Criteria Under Which Filtration Is Required § 142.80 Review procedures. (a) The Administrator...

  11. 40 CFR 142.80 - Review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Review procedures. 142.80 Section 142...) NATIONAL PRIMARY DRINKING WATER REGULATIONS IMPLEMENTATION Administrator's Review of State Decisions that Implement Criteria Under Which Filtration Is Required § 142.80 Review procedures. (a) The Administrator...

  12. 33 CFR 331.7 - Review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Review procedures. 331.7 Section... DEFENSE ADMINISTRATIVE APPEAL PROCESS § 331.7 Review procedures. (a) General. The administrative appeal... permits. Upon receipt of an RFA, the RO shall review the RFA to determine whether the RFA is acceptable...

  13. 33 CFR 331.7 - Review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Review procedures. 331.7 Section... DEFENSE ADMINISTRATIVE APPEAL PROCESS § 331.7 Review procedures. (a) General. The administrative appeal... permits. Upon receipt of an RFA, the RO shall review the RFA to determine whether the RFA is acceptable...

  14. 33 CFR 331.7 - Review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Review procedures. 331.7 Section... DEFENSE ADMINISTRATIVE APPEAL PROCESS § 331.7 Review procedures. (a) General. The administrative appeal... permits. Upon receipt of an RFA, the RO shall review the RFA to determine whether the RFA is acceptable...

  15. 33 CFR 331.7 - Review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Review procedures. 331.7 Section... DEFENSE ADMINISTRATIVE APPEAL PROCESS § 331.7 Review procedures. (a) General. The administrative appeal... permits. Upon receipt of an RFA, the RO shall review the RFA to determine whether the RFA is acceptable...

  16. 33 CFR 331.7 - Review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Review procedures. 331.7 Section... DEFENSE ADMINISTRATIVE APPEAL PROCESS § 331.7 Review procedures. (a) General. The administrative appeal... permits. Upon receipt of an RFA, the RO shall review the RFA to determine whether the RFA is acceptable...

  17. PriMux

    Energy Science and Technology Software Center (ESTSC)

    2010-08-31

    PriMux is used to compute sets of compatible Polymerase Chain Reaction (PCR)signatures that can be used for detecting the presence of biological species in a small sample of material. Before use, the computed signatures must be empirically tested in a wet lab.

  18. 13 CFR 117.10 - Review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Review procedures. 117.10 Section 117.10 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS OR ACTIVITIES OF SBA-EFFECTUATION OF THE AGE DISCRIMINATION ACT OF 1975, AS AMENDED § 117.10 Review procedures. (a) SBA shall...

  19. 12 CFR 1408.10 - Review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Review procedures. 1408.10 Section 1408.10 Banks and Banking FARM CREDIT SYSTEM INSURANCE CORPORATION COLLECTION OF CLAIMS OWED THE UNITED STATES Administrative Collection of Claims § 1408.10 Review procedures. (a) Unless an oral hearing is required by § 1408.23(d), the Corporation's...

  20. 12 CFR 608.810 - Review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Review procedures. 608.810 Section 608.810 Banks and Banking FARM CREDIT ADMINISTRATION ADMINISTRATIVE PROVISIONS COLLECTION OF CLAIMS OWED THE UNITED STATES Administrative Collection of Claims § 608.810 Review procedures. (a) Unless an oral hearing is required by § 608.823(d), the FCA's...

  1. 12 CFR 608.810 - Review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 7 2012-01-01 2012-01-01 false Review procedures. 608.810 Section 608.810 Banks and Banking FARM CREDIT ADMINISTRATION ADMINISTRATIVE PROVISIONS COLLECTION OF CLAIMS OWED THE UNITED STATES Administrative Collection of Claims § 608.810 Review procedures. (a) Unless an oral hearing is required by § 608.823(d), the FCA's...

  2. 49 CFR 601.47 - Review Procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Review Procedures. 601.47 Section 601.47 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ORGANIZATION, FUNCTIONS, AND PROCEDURES Emergency Procedures for...

  3. 49 CFR 601.47 - Review Procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 7 2013-10-01 2013-10-01 false Review Procedures. 601.47 Section 601.47 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ORGANIZATION, FUNCTIONS, AND PROCEDURES Emergency Procedures for...

  4. 49 CFR 601.47 - Review Procedures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 7 2012-10-01 2012-10-01 false Review Procedures. 601.47 Section 601.47 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ORGANIZATION, FUNCTIONS, AND PROCEDURES Emergency Procedures for...

  5. 49 CFR 601.47 - Review Procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 7 2014-10-01 2014-10-01 false Review Procedures. 601.47 Section 601.47 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ORGANIZATION, FUNCTIONS, AND PROCEDURES Emergency Procedures for...

  6. 13 CFR 117.10 - Review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ASSISTED PROGRAMS OR ACTIVITIES OF SBA-EFFECTUATION OF THE AGE DISCRIMINATION ACT OF 1975, AS AMENDED § 117.10 Review procedures. (a) SBA shall from time to time review the practices of recipients to determine whether they are complying with this part. As part of a compliance review or complaint investigation,...

  7. 39 CFR 776.5 - Review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Service UNITED STATES POSTAL SERVICE ENVIRONMENTAL REGULATIONS FLOODPLAIN AND WETLAND PROCEDURES Floodplain Management § 776.5 Review procedures. Officials shall follow the decision-making process outlined in paragraphs (a) through (f) of this section, when a facility action may involve floodplain...

  8. 39 CFR 776.5 - Review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Service UNITED STATES POSTAL SERVICE ENVIRONMENTAL REGULATIONS FLOODPLAIN AND WETLAND PROCEDURES Floodplain Management § 776.5 Review procedures. Officials shall follow the decision-making process outlined in paragraphs (a) through (f) of this section, when a facility action may involve floodplain...

  9. 39 CFR 776.5 - Review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Service UNITED STATES POSTAL SERVICE ENVIRONMENTAL REGULATIONS FLOODPLAIN AND WETLAND PROCEDURES Floodplain Management § 776.5 Review procedures. Officials shall follow the decision-making process outlined in paragraphs (a) through (f) of this section, when a facility action may involve floodplain...

  10. 39 CFR 776.5 - Review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Service UNITED STATES POSTAL SERVICE ENVIRONMENTAL REGULATIONS FLOODPLAIN AND WETLAND PROCEDURES Floodplain Management § 776.5 Review procedures. Officials shall follow the decision-making process outlined in paragraphs (a) through (f) of this section, when a facility action may involve floodplain...

  11. 39 CFR 776.5 - Review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Service UNITED STATES POSTAL SERVICE ENVIRONMENTAL REGULATIONS FLOODPLAIN AND WETLAND PROCEDURES Floodplain Management § 776.5 Review procedures. Officials shall follow the decision-making process outlined in paragraphs (a) through (f) of this section, when a facility action may involve floodplain...

  12. 12 CFR 797.9 - Review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... appendix A to 5 CFR part 581 to arrange for a hearing official. When NCUA is the creditor agency and the... the paying agency designated in appendix A to 5 CFR part 581 to arrange for a hearing official. The... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Review procedures. 797.9 Section 797.9...

  13. Reviewing the College Disciplinary Procedure. Mendip Papers.

    ERIC Educational Resources Information Center

    Kedney, R. J.; Saunders, R.

    This paper provides practical advice on reviewing and designing disciplinary procedures and is set in the context of incorporation of further education and sixth form colleges in England. Reasons are provided for having disciplinary rules, based on the Advisory Conciliation and Arbitration Service's (ACAS) Code of Practice. Relevant English…

  14. 12 CFR 797.9 - Review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... appendix A to 5 CFR part 581 to arrange for a hearing official. When NCUA is the creditor agency and the... the paying agency designated in appendix A to 5 CFR part 581 to arrange for a hearing official. The... 12 Banks and Banking 7 2014-01-01 2014-01-01 false Review procedures. 797.9 Section 797.9...

  15. 12 CFR 797.9 - Review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... appendix A to 5 CFR part 581 to arrange for a hearing official. When NCUA is the creditor agency and the... the paying agency designated in appendix A to 5 CFR part 581 to arrange for a hearing official. The... 12 Banks and Banking 7 2013-01-01 2013-01-01 false Review procedures. 797.9 Section 797.9...

  16. Year 2000 TWRS Maintenance procedure review report

    SciTech Connect

    ADAMS, M.R.

    1999-02-24

    A concern exists that some equipment in use might contain microprocessors that are dependent upon a time date function. The majority of the software programming for microprocessors has only utilized a 2 digit identifier for the year. With the approach of the year 2000, (Y2K), there is concern that the date function will not be correctly recognized and some functions will not operate properly. TWRS maintenance procedures have been reviewed to identify equipment components that may not be Y2K compliant. Engineering judgment was utilized to eliminate procedures and equipment that is obviously not impacted by Y2K.

  17. 28 CFR 34.102 - Peer review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Peer review procedures. 34.102 Section 34.102 Judicial Administration DEPARTMENT OF JUSTICE OJJDP COMPETITION AND PEER REVIEW PROCEDURES Peer Review § 34.102 Peer review procedures. The OJJDP peer review process is contained in an OJJDP...

  18. 28 CFR 34.102 - Peer review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Peer review procedures. 34.102 Section 34.102 Judicial Administration DEPARTMENT OF JUSTICE OJJDP COMPETITION AND PEER REVIEW PROCEDURES Peer Review § 34.102 Peer review procedures. The OJJDP peer review process is contained in an OJJDP...

  19. 28 CFR 34.102 - Peer review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Peer review procedures. 34.102 Section 34.102 Judicial Administration DEPARTMENT OF JUSTICE OJJDP COMPETITION AND PEER REVIEW PROCEDURES Peer Review § 34.102 Peer review procedures. The OJJDP peer review process is contained in an OJJDP...

  20. 28 CFR 34.102 - Peer review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Peer review procedures. 34.102 Section 34.102 Judicial Administration DEPARTMENT OF JUSTICE OJJDP COMPETITION AND PEER REVIEW PROCEDURES Peer Review § 34.102 Peer review procedures. The OJJDP peer review process is contained in an OJJDP...

  1. 28 CFR 34.102 - Peer review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Peer review procedures. 34.102 Section 34.102 Judicial Administration DEPARTMENT OF JUSTICE OJJDP COMPETITION AND PEER REVIEW PROCEDURES Peer Review § 34.102 Peer review procedures. The OJJDP peer review process is contained in an OJJDP...

  2. Pectoralis major tendon rupture. Surgical procedures review.

    PubMed Central

    Merolla, Giovanni; Paladini, Paolo; Campi, Fabrizio; Porcellini, Giuseppe

    2012-01-01

    Summary Pectoralis major (PM) muscle is the powerful dynamic stabiliser of the shoulder that acts as a flexor, adductor and internal rotator. The rupture of the PM tendon is a relatively rare injury that was firstly described in a French boy by Patissier in 1822 and later, in 1861, by Letenneur who reported another similiar case. To date, over 200 cases have been published. In this article we describe the clinical anatomy and the mechanism of injuries of PM and we review the surgical procedures for acute and chronic ruptures. PMID:23738281

  3. [Mood induction procedures: a critical review].

    PubMed

    Gilet, A-L

    2008-06-01

    For a long period in the history of psychological research, emotion and cognition have been studied independently, as if one were irrelevant to the other. The renewed interest of researchers for the study of the relations between cognition and emotion has led to the development of a range of laboratory methods for inducing temporary mood states. This paper aims to review the main mood induction procedures allowing the induction of a negative mood as well as a positive mood, developed since the pioneer study of Schachter and Singer [Psychol Rev 69 (1962) 379-399] and to account for the usefulness and problems related to the use of such techniques. The first part of this paper deals with the detailed presentation of some of the most popular mood induction procedures according to their type: simple (use of only one mood induction technique) or combined (association of two or more techniques at once). The earliest of the modern techniques is the Velten Mood Induction Procedure [Behav Res Ther 6 (1968) 473-482], which involves reading aloud sixty self-referent statements progressing from relative neutral mood to negative mood or dysphoria. Some researchers have varied the procedure slightly by changing the number of the statements [Behav Res Ther 21 (1983) 233-239, Br J Clin Psychol 21 (1982) 111-117, J Pers Soc Psychol 35 (1977) 625-636]. Various other mood induction procedures have been developed including music induction [Cogn Emotion 11 (1997) 403-432, Br J Med Psychol 55 (1982) 127-138], film clip induction [J Pers Soc Psychol 20 (1971) 37-43, Cogn Emotion 7 (1993) 171-193, Rottenberg J, Ray RR, Gross JJ. Emotion elicitation using films. In: Coan JA, Allen JJB, editors. The handbook of emotion elicitation and assessment. New York: Oxford University Press, 2007], autobiographical recall [J Clin Psychol 36 (1980) 215-226, Jallais C. Effets des humeurs positives et négatives sur les structures de connaissances de type script. Thèse de doctorat non publi

  4. 33 CFR 51.9 - Discharge review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Discharge review procedures. 51.9 Section 51.9 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PERSONNEL COAST GUARD DISCHARGE REVIEW BOARD § 51.9 Discharge review procedures. (a) Preliminary. Prior to a review, applicants or their representatives...

  5. 33 CFR 51.9 - Discharge review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Discharge review procedures. 51.9 Section 51.9 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PERSONNEL COAST GUARD DISCHARGE REVIEW BOARD § 51.9 Discharge review procedures. (a) Preliminary. Prior to a review, applicants or their representatives...

  6. Comprehensive medication review: development of a collaborative procedure.

    PubMed

    Leikola, Saija; Tuomainen, Lea; Peura, Sirpa; Laurikainen, Antti; Lyles, Alan; Savela, Eeva; Airaksinen, Marja

    2012-08-01

    This commentary describes the development and evidence-base of the Comprehensive Medication Review (CMR) procedure for community and hospital settings in Finland. The development was coordinated by a national steering group. The group collaborated with 26 experienced pharmacists who developed and tested CMR procedures during a 1.5 year accreditation training for CMR. The development consisted of: (1) a literature review and inventory of medication review procedures in different countries; (2) the creation of potential procedures and related documentation; (3) integration of potential procedures into a national standard procedure; and (4) piloting the standard procedure in practice settings. The resulting comprehensive medication review procedure requires access to a patient's clinical information, an in-home patient interview and a case conference with the collaborating physician. This procedure covers the four main dimensions critical for safe and appropriate geriatric pharmacotherapy: aging and safety; co-morbidities; polypharmacy; and adherence. The CMR measures and documentation build on these dimensions. PMID:22711383

  7. 23 CFR 230.409 - Contract compliance review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Contract compliance review procedures. 230.409 Section 230.409 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS EXTERNAL PROGRAMS Construction Contract Equal Opportunity Compliance Procedures § 230.409 Contract compliance review procedures. (a) General. A...

  8. 48 CFR 13.303-6 - Review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Review procedures. 13.303... Review procedures. (a) The contracting officer placing orders under a BPA, or the designated representative of the contracting officer, shall review a sufficient random sample of the BPA files at...

  9. 22 CFR 61.7 - Review and appeal procedures.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Review and appeal procedures. 61.7 Section 61.7 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.7 Review and appeal procedures. (a) An applicant may request a formal review of any...

  10. 22 CFR 61.7 - Review and appeal procedures.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Review and appeal procedures. 61.7 Section 61.7 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.7 Review and appeal procedures. (a) An applicant may request a formal review of any...

  11. 22 CFR 61.7 - Review and appeal procedures.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Review and appeal procedures. 61.7 Section 61.7 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.7 Review and appeal procedures. (a) An applicant may request a formal review of any...

  12. 22 CFR 61.7 - Review and appeal procedures.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Review and appeal procedures. 61.7 Section 61.7 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.7 Review and appeal procedures. (a) An applicant may request a formal review of any...

  13. 42 CFR 431.980 - Eligibility review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Estimating Improper Payments in Medicaid and CHIP § 431.980 Eligibility review procedures. (a) Active case reviews. The agency must verify eligibility for all selected active cases for Medicaid and CHIP for the... must review all selected negative cases for Medicaid and CHIP for the review month to determine...

  14. Procedures for Peer Review of Reports

    ERIC Educational Resources Information Center

    US Department of Education, 2006

    2006-01-01

    Under the Education Sciences Reform Act, all research, statistics, and evaluation reports conducted by, or supported through, the Institute shall be subject to rigorous peer review before being published or otherwise made available to the public. Prior to review and approval by the NCEE Commissioner, NCEE reports are reviewed internally by the…

  15. 75 FR 15689 - Streamlined Procedure for Appeal Brief Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-30

    ... United States Patent and Trademark Office Streamlined Procedure for Appeal Brief Review AGENCY: United... Trademark Office (USPTO) is streamlining the procedure for the review of appeal briefs to increase the... responsibility for determining whether appeal briefs filed in patent applications comply with the...

  16. 25 CFR 13.14 - Secretarial review procedure.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Secretarial review procedure. 13.14 Section 13.14 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER TRIBAL REASSUMPTION OF JURISDICTION OVER CHILD CUSTODY PROCEEDINGS Reassumption § 13.14 Secretarial review procedure. (a) Upon receipt...

  17. 25 CFR 13.14 - Secretarial review procedure.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Secretarial review procedure. 13.14 Section 13.14 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER TRIBAL REASSUMPTION OF JURISDICTION OVER CHILD CUSTODY PROCEEDINGS Reassumption § 13.14 Secretarial review procedure. (a) Upon receipt...

  18. 25 CFR 13.14 - Secretarial review procedure.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Secretarial review procedure. 13.14 Section 13.14 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER TRIBAL REASSUMPTION OF JURISDICTION OVER CHILD CUSTODY PROCEEDINGS Reassumption § 13.14 Secretarial review procedure. (a) Upon receipt...

  19. 25 CFR 13.14 - Secretarial review procedure.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Secretarial review procedure. 13.14 Section 13.14 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER TRIBAL REASSUMPTION OF JURISDICTION OVER CHILD CUSTODY PROCEEDINGS Reassumption § 13.14 Secretarial review procedure. (a) Upon receipt...

  20. 25 CFR 13.14 - Secretarial review procedure.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Secretarial review procedure. 13.14 Section 13.14 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER TRIBAL REASSUMPTION OF JURISDICTION OVER CHILD CUSTODY PROCEEDINGS Reassumption § 13.14 Secretarial review procedure. (a) Upon receipt...

  1. 29 CFR 801.69 - Procedures for initiating review.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Procedures for initiating review. 801.69 Section 801.69 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS... Vacation of Decision and Order of Administrative Law Judge § 801.69 Procedures for initiating review....

  2. MISR Browse Images: Puerto Rico Dust Experiment (PRiDE)

    Atmospheric Science Data Center

    2013-04-02

    MISR Browse Images: Puerto Rico Dust Experiment (PRiDE) These MISR Browse images provide ... overview of the region observed during the Puerto Rico Dust Experiment (PRiDE) field campaign. PRiDE was a study of the radiative, ...

  3. 22 CFR 61.7 - Review and appeal procedures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Review and appeal procedures. 61.7 Section 61.7 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.7 Review and appeal procedures. (a) An applicant may request a formal review of any adverse ruling rendered by the...

  4. Program Review/Evaluation Policy and Procedures.

    ERIC Educational Resources Information Center

    Colorado Northwestern Community Coll., Rangely.

    At Colorado Northwestern Community College (CNCC), all educational programs, as well as student services and support functions, are formally reviewed/evaluated in depth at least once every five years. This nine-part outline, providing a step-by-step description of the program review process at CNCC, includes the following sections: (1) the value…

  5. 48 CFR 242.7203 - Review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... evaluation. Cognizant contract administration and audit activities must jointly establish and manage programs... to be reviewed. In addition, they must— (1) Conduct reviews as a team effort. (i) the ACO— (A) Appoints a team leader; and (B) Ensures that the team includes appropriate functional specialists...

  6. 48 CFR 13.303-6 - Review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Review procedures. (a) The contracting officer placing orders under a BPA, or the designated representative of the contracting officer, shall review a sufficient random sample of the BPA files at least... into the BPA shall— (1) Ensure that each BPA is reviewed at least annually and, if necessary,...

  7. 48 CFR 13.303-6 - Review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Review procedures. (a) The contracting officer placing orders under a BPA, or the designated representative of the contracting officer, shall review a sufficient random sample of the BPA files at least... into the BPA shall— (1) Ensure that each BPA is reviewed at least annually and, if necessary,...

  8. 48 CFR 13.303-6 - Review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Review procedures. (a) The contracting officer placing orders under a BPA, or the designated representative of the contracting officer, shall review a sufficient random sample of the BPA files at least... into the BPA shall— (1) Ensure that each BPA is reviewed at least annually and, if necessary,...

  9. 48 CFR 13.303-6 - Review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Review procedures. (a) The contracting officer placing orders under a BPA, or the designated representative of the contracting officer, shall review a sufficient random sample of the BPA files at least... into the BPA shall— (1) Ensure that each BPA is reviewed at least annually and, if necessary,...

  10. 42 CFR 476.130 - Beneficiary complaint review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Beneficiary complaint review procedures. 476.130 Section 476.130 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) QUALITY IMPROVEMENT ORGANIZATIONS QUALITY IMPROVEMENT ORGANIZATION REVIEW Review Responsibilities of Quality...

  11. 42 CFR 476.130 - Beneficiary complaint review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Beneficiary complaint review procedures. 476.130 Section 476.130 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) QUALITY IMPROVEMENT ORGANIZATIONS UTILIZATION AND QUALITY CONTROL REVIEW Review Responsibilities of Utilization and...

  12. 48 CFR 1552.237-70 - Contract publication review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contract publication review... 1552.237-70 Contract publication review procedures. As prescribed in 1537.110, insert the following contract clause when the products of the contract are subject to contract publication review....

  13. Linking Knowledge and Action: PRI's Community Consultant.

    ERIC Educational Resources Information Center

    Spencer, Gregory P.

    Within the Partnership for Rural Improvement (PRI), community consultants operate within three complex sets of relationships: client groups, the organizational structure of PRI, and the local operational base. Community consultants are responsible for developing and facilitating rural development and for providing assistance in community and…

  14. Procedural and Conceptual Knowledge: Adults Reviewing Fractions

    ERIC Educational Resources Information Center

    Baker, William J.; Czarnocha, Bronislaw; Dias, Olen; Doyle, Kathleen; Kennis, James R.

    2012-01-01

    In the United States a majority of the students who enroll in community colleges require a review of secondary math before they are eligible for college level mathematics. In the pre-algebra course, that has a high drop-out rate, the most difficult topic for students is fractions. In order to better understand the fraction concept, Kieren…

  15. A Review of the Literature Related to the Cloze Procedure.

    ERIC Educational Resources Information Center

    Fram, Ralph D.

    This review of the literature related to the cloze procedure includes most of the studies reported from 1953 to 1971. One hundred ninety-eight documents are included and are divided into four categories, studies in which the cloze procedure has been applied (1) as a measure of readability, (2) as a measure of comprehension, (3) as a measure of…

  16. 46 CFR 272.43 - Review and appeal procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Review and appeal procedures. 272.43 Section 272.43 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS AFFECTING SUBSIDIZED VESSELS AND OPERATORS REQUIREMENTS AND PROCEDURES FOR CONDUCTING CONDITION SURVEYS AND ADMINISTERING MAINTENANCE...

  17. 14 CFR 435.33 - Safety review requirements and procedures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Safety review requirements and procedures. 435.33 Section 435.33 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING REENTRY OF A REENTRY VEHICLE OTHER THAN A REUSABLE LAUNCH VEHICLE (RLV) Safety Review and...

  18. 14 CFR 435.23 - Policy review requirements and procedures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Policy review requirements and procedures. 435.23 Section 435.23 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING REENTRY OF A REENTRY VEHICLE OTHER THAN A REUSABLE LAUNCH VEHICLE (RLV) Policy Review and...

  19. 42 CFR 431.980 - Eligibility review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ....980 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Estimating Improper Payments in Medicaid and CHIP § 431.980 Eligibility review procedures. (a) Active case reviews. The agency must verify eligibility for all selected active cases for Medicaid and CHIP for...

  20. 42 CFR 431.980 - Eligibility review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ....980 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Estimating Improper Payments in Medicaid and CHIP § 431.980 Eligibility review procedures. (a) Active case reviews. The agency must verify eligibility for all selected active cases for Medicaid and CHIP for...

  1. 76 FR 4933 - Environmental Review Procedures for Entities Assuming HUD Environmental Review Responsibilities...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-27

    ... Responsibilities; Notice of Proposed Information Collection: Comment Request AGENCY: Office of the Assistant...: Environmental Review Procedures for Entities Assuming HUD Environmental Responsibilities. OMB Control...

  2. Standard Review Plan Update and Development Program. Implementing Procedures Document

    SciTech Connect

    Not Available

    1992-05-01

    This implementing procedures document (IPD) was prepared for use in implementing tasks under the standard review plan update and development program (SRP-UDP). The IPD provides comprehensive guidance and detailed procedures for SRP-UDP tasks. The IPD is mandatory for contractors performing work for the SRP-UDP. It is guidance for the staff. At the completion of the SRP-UDP, the IPD will be revised (to remove the UDP aspects) and will replace NRR Office Letter No. 800 as long-term maintenance procedures.

  3. Review of mountain river training procedures in Switzerland

    NASA Astrophysics Data System (ADS)

    Willi, Hans Peter

    The violent storms which occurred in Switzerland in 1987 caused damage to the tune of 1.2 to 1.3 billion Swiss francs. Numerous constructional measures had to be taken to protect against floods. The 1987 catastrophe asked for a fundamental review of flood protection measures from a number of different viewpoints. After a short review and general explanations about topographical attributes, precipitations, geology, political conditions and the legal situation in Switzerland, the actual guidelines for river training procedures were presented.

  4. 15 CFR 960.6 - Review procedures for license applications.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 3 2013-01-01 2013-01-01 false Review procedures for license applications. 960.6 Section 960.6 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA...

  5. 15 CFR 960.6 - Review procedures for license applications.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 3 2011-01-01 2011-01-01 false Review procedures for license applications. 960.6 Section 960.6 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA...

  6. 15 CFR 960.6 - Review procedures for license applications.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Review procedures for license applications. 960.6 Section 960.6 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA...

  7. 42 CFR 417.840 - Administrative review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Administrative review procedures. 417.840 Section 417.840 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM HEALTH MAINTENANCE ORGANIZATIONS, COMPETITIVE MEDICAL PLANS,...

  8. 42 CFR 417.840 - Administrative review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 3 2011-10-01 2011-10-01 false Administrative review procedures. 417.840 Section 417.840 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM HEALTH MAINTENANCE ORGANIZATIONS, COMPETITIVE MEDICAL PLANS,...

  9. 42 CFR 417.840 - Administrative review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 3 2012-10-01 2012-10-01 false Administrative review procedures. 417.840 Section 417.840 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM (CONTINUED) HEALTH MAINTENANCE ORGANIZATIONS, COMPETITIVE...

  10. 42 CFR 417.840 - Administrative review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 3 2013-10-01 2013-10-01 false Administrative review procedures. 417.840 Section 417.840 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM (CONTINUED) HEALTH MAINTENANCE ORGANIZATIONS, COMPETITIVE...

  11. 42 CFR 417.840 - Administrative review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 3 2014-10-01 2014-10-01 false Administrative review procedures. 417.840 Section 417.840 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM (CONTINUED) HEALTH MAINTENANCE ORGANIZATIONS, COMPETITIVE...

  12. 40 CFR 501.31 - Review and approval procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 31 2013-07-01 2013-07-01 false Review and approval procedures. 501.31 Section 501.31 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SEWAGE SLUDGE STATE... sewage listed on the inventory required by § 501.12(f) of this part. The notice will: (1) Provide...

  13. 40 CFR 501.31 - Review and approval procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 30 2014-07-01 2014-07-01 false Review and approval procedures. 501.31 Section 501.31 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SEWAGE SLUDGE STATE... sewage listed on the inventory required by § 501.12(f) of this part. The notice will: (1) Provide...

  14. 40 CFR 501.31 - Review and approval procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Review and approval procedures. 501.31 Section 501.31 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SEWAGE SLUDGE STATE... sewage listed on the inventory required by § 501.12(f) of this part. The notice will: (1) Provide...

  15. 40 CFR 501.31 - Review and approval procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 31 2012-07-01 2012-07-01 false Review and approval procedures. 501.31 Section 501.31 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SEWAGE SLUDGE STATE... sewage listed on the inventory required by § 501.12(f) of this part. The notice will: (1) Provide...

  16. 40 CFR 501.31 - Review and approval procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 30 2011-07-01 2011-07-01 false Review and approval procedures. 501.31 Section 501.31 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SEWAGE SLUDGE STATE... sewage listed on the inventory required by § 501.12(f) of this part. The notice will: (1) Provide...

  17. 42 CFR 405.1834 - CMS reviewing official procedure.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 2 2011-10-01 2011-10-01 false CMS reviewing official procedure. 405.1834 Section 405.1834 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM FEDERAL HEALTH INSURANCE FOR THE AGED AND DISABLED Provider Reimbursement Determinations and Appeals § 405.1834 CMS...

  18. 33 CFR 154.1065 - Plan review and revision procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SECURITY (CONTINUED) POLLUTION FACILITIES TRANSFERRING OIL OR HAZARDOUS MATERIAL IN BULK Response Plans for Oil Facilities § 154.1065 Plan review and revision procedures. (a) A facility owner or operator must..., including listings of fish and wildlife and sensitive environments identified in the ACP in effect 6...

  19. 45 CFR 1355.33 - Procedures for the review.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... State was required to consult in developing its CFSP, as described and required in 45 CFR part 1357.15(l... in the development of the State's CFSP required at 45 CFR 1357.15(1), courts, administrative review... MAINTENANCE PAYMENTS, ADOPTION ASSISTANCE, AND CHILD AND FAMILY SERVICES GENERAL § 1355.33 Procedures for...

  20. 42 CFR 431.980 - Eligibility review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Eligibility review procedures. 431.980 Section 431.980 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STATE ORGANIZATION AND GENERAL ADMINISTRATION Requirements for Estimating Improper Payments in Medicaid...

  1. 7 CFR 929.125 - Committee review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Committee review procedures. 929.125 Section 929.125 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE CRANBERRIES GROWN IN STATES...

  2. 7 CFR 929.125 - Committee review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Committee review procedures. 929.125 Section 929.125 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE CRANBERRIES GROWN IN STATES...

  3. 7 CFR 929.125 - Committee review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Committee review procedures. 929.125 Section 929.125 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE CRANBERRIES GROWN IN STATES...

  4. 7 CFR 929.125 - Committee review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Committee review procedures. 929.125 Section 929.125 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE CRANBERRIES GROWN IN STATES...

  5. 7 CFR 929.125 - Committee review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Committee review procedures. 929.125 Section 929.125 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE CRANBERRIES GROWN IN STATES...

  6. 48 CFR 1552.237-70 - Contract publication review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Contract publication... Clauses 1552.237-70 Contract publication review procedures. As prescribed in 1537.110, insert the following contract clause when the products of the contract are subject to contract publication...

  7. 29 CFR 801.69 - Procedures for initiating review.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Procedures for initiating review. 801.69 Section 801.69 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS APPLICATION OF THE EMPLOYEE POLYGRAPH PROTECTION ACT OF 1988 Administrative Proceedings Modification...

  8. 29 CFR 801.69 - Procedures for initiating review.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Procedures for initiating review. 801.69 Section 801.69 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS APPLICATION OF THE EMPLOYEE POLYGRAPH PROTECTION ACT OF 1988 Administrative Proceedings Modification...

  9. 29 CFR 801.69 - Procedures for initiating review.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Procedures for initiating review. 801.69 Section 801.69 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS APPLICATION OF THE EMPLOYEE POLYGRAPH PROTECTION ACT OF 1988 Administrative Proceedings Modification...

  10. 29 CFR 801.69 - Procedures for initiating review.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Procedures for initiating review. 801.69 Section 801.69 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS APPLICATION OF THE EMPLOYEE POLYGRAPH PROTECTION ACT OF 1988 Administrative Proceedings Modification...

  11. 29 CFR 500.264 - Procedures for initiating review.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Procedures for initiating review. 500.264 Section 500.264 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS MIGRANT AND SEASONAL AGRICULTURAL WORKER PROTECTION Administrative Proceedings Modification Or Vacation...

  12. 29 CFR 500.264 - Procedures for initiating review.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Procedures for initiating review. 500.264 Section 500.264 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS MIGRANT AND SEASONAL AGRICULTURAL WORKER PROTECTION Administrative Proceedings Modification Or Vacation...

  13. Review of the IEEE Standard for Computerized Operating Procedure Systems

    SciTech Connect

    O'Hara, J.; Higgins, J.

    2010-02-26

    Increasingly nuclear power plant procedures, such as emergency operating procedures, are being presented in computer form with functionality to support operator use and management of the procedures. The U.S. Nuclear Regulatory Commission (NRC) currently has guidance for the review of computer-based procedures (CBPs); however, there remain CBP functions and human performance issues for which up-to-date guidance is lacking. The Institute of Electrical and Electronics Engineers (IEEE) has initiated a standard development effort to address the human factors engineering (HFE) aspects of CBP systems. When completed, it may provide guidance to supplement the NRC staff's review criteria. The purpose of our study was to evaluate the suitability of the IEEE Standard for use in the NRC's HFE safety reviews of CBP systems and to ensure that the guidance meets the NRC's standard for scientific and engineering rigor used in its own guidance development efforts. We established the following criteria with which to evaluate the Standard: (1) it should meet an existing need of NRC reviewers, (2) it should be based in sound HFE principles, (3) it should be thoroughly peer-reviewed, and (4) it should address CBP-related human performance issues identified in the literature. This report describes the methodology we used to evaluate each criterion. Our evaluation concluded that the Standard generally does meet these criteria, however several areas were identified for which additional clarifications are needed. Thus consideration of the Standard's use by the NRC is supported. The standard evaluation methodology developed in this study can be generally applied to the review of other HFE standards being considered for possible use or endorsement by the NRC.

  14. Neurosurgical procedures in patients with liver cirrhosis: A review

    PubMed Central

    Chen, Ching-Chang; Huang, Yin-Cheng; Yeh, Chun-Nan

    2015-01-01

    Liver cirrhosis, a devastating liver fibrosis caused by hepatitis/inflammation or tumors, is a major comorbid factor in known surgery fields, such as cardiovascular and abdominal surgeries. It is important to review possible comorbid results in neurosurgical procedures in cirrhotic patients. In the reviewed literature, Child-Pugh and model for end-stage liver disease scores are commonly used in the assessment of surgical risks for cirrhotic patients undergoing abdominal, cardiovascular or neurosurgical procedures. The major categories of neurosurgery are traumatic brain injury (TBI), spontaneous intracranial hemorrhage (SICH), brain tumors, and spinal instrumentation procedures. TBI was reported with surgical mortality as high as 34.5% and a complication rate of 87.2%. For SICH, mortality ranged from 22.7% to 47.0%, while complications were reported to be 43.2%. Less is discussed in brain tumor patients; still the postoperative hemorrhage rate approached 26.7%. In spinal fusion instrumentation procedures, the complication rate was as high as 41.0%. Preoperative assessment and correction could possibly decrease complications such as hemorrhage, wound infection and other cirrhosis-related complications (renal, pulmonary, ascites and encephalopathy). In this study, we reviewed the neurosurgical-related literature with regard to liver cirrhosis as a prognostic factor influencing neurosurgical outcomes. PMID:26413225

  15. Ultrasound-Guided Spinal Procedures for Pain: A Review.

    PubMed

    Hurdle, Mark-Friedrich B

    2016-08-01

    As the population ages, more patients are developing degenerative changes of the spine and associated pain. Although interventional procedures for axial and radicular spine pain have been available for decades, common imaging modalities have relied on ionizing radiation for guidance. Over the past decade, ultrasound has become increasingly popular to image both peripheral musculoskeletal and axial structures. This article reviews the use of ultrasound in the guidance of spine procedures, including cervical and lumbar facet injections and medial branch blocks, third occipital nerve blocks, thoracic facet and costotransverse joint injections, sacroiliac joint injections, and caudal and interlaminar epidural injections. PMID:27468672

  16. DnaT is a PriC-binding protein.

    PubMed

    Huang, Chien-Chih; Huang, Cheng-Yang

    2016-09-01

    DnaT and PriC are replication restart primosomal proteins required for re-initiating chromosomal DNA replication. DnaT is a component of the PriA-dependent primosome, while PriC belongs to the PriC-dependent primosome. Whether DnaT can interact with PriC is still unknown. In this study, we define a direct interaction between PriC, a key initiator protein in PriC-mediated DNA replication restart, and DnaT, a DnaB/C complex loader protein, from Klebsiella pneumoniae. In fluorescence titrations, PriC bound to single-stranded DNA with a binding-site size of approximately 9 nt. Gold nanoparticle assay showed that the solution of DnaT-PriC changed from red to purple, which indicated the protein-protein interactions due to gold nanoparticle aggregate. In addition, this DnaT-PriC complex could be co-purified by the heparin HP column. Surface plasmon resonance analysis showed that the Kd value of DnaT bound to PriC was 2.9 × 10(-8) M. These results constitute a pioneering study of the DnaT-PriC interaction and present a putative link between the two independent replication restart pathways, namely, PriA- and PriC-dependent primosome assemblies. Further research can directly focus on determining how DnaT binds to the PriC-SSB-DNA tricomplex and regulates the PriC-dependent replication restart. PMID:27387236

  17. [Ultrasound guided radial artery cannulation: procedure description and literature review].

    PubMed

    Carmona Monge, F J; Martínez Lareo, M; Núñez Reiz, A

    2011-01-01

    Arterial catheterization is the second most common invasive procedure performed in critical care units. These devices are essential in certain types of patients (the hemodinamically unstable or those who require regular evaluation of the gasometric values). Complications related to arterial cannulation are relatively scarce. However, there are no reliable indicators to predict the occurrence of radial artery occlusions or ischemic lesions in the hand after a radial cannulation procedure has been performed. Ultrasound-guided catheter insertion has been used for years to guide central venous cannulation in critical care, but its use has been more limited for arterial catheterization. This paper aims to describe the technique of ultrasound-guided radial artery catheterization and reviews the most important research papers that have evaluated the safety and efficacy of this procedure in the adult population. PMID:21256787

  18. Effectiveness of granite cleaning procedures in cultural heritage: A review.

    PubMed

    Pozo-Antonio, J S; Rivas, T; López, A J; Fiorucci, M P; Ramil, A

    2016-11-15

    Most of the Cultural Heritage built in NW Iberian Peninsula is made of granite which exposition to the environment leads to the formation of deposits and coatings, mainly two types: biological colonization and sulphated black crusts. Nowadays, another form of alteration derives from graffiti paints when these are applied as an act of vandalism. A deep revision needs to be addressed considering the severity of these deterioration forms on granite and the different cleaning effectiveness achieved by cleaning procedures used to remove them. The scientific literature about these topics on granite is scarcer than on sedimentary carbonate stones and marbles, but the importance of the granite in NW Iberian Peninsula Cultural Heritage claims this review centred on biological colonization, sulphated black crusts and graffiti on granite and their effectiveness of the common cleaning procedures. Furthermore, this paper carried out a review of the knowledge about those three alteration forms on granite, as well as bringing together all the major studies in the field of the granite cleaning with traditional procedures (chemical and mechanical) and with the recent developed technique based on the laser ablation. Findings concerning the effectiveness evaluation of these cleaning procedures, considering the coating extraction ability and the damage induced on the granite surface, are described. Finally, some futures research lines are pointed out. PMID:27443454

  19. Deinococcus radiodurans PriA is a Pseudohelicase

    PubMed Central

    Lopper, Matthew E.; Boone, Jacob; Morrow, Christopher

    2015-01-01

    Reactivation of repaired DNA replication forks in bacteria is catalyzed by PriA helicase. This broadly-conserved bacterial enzyme can remodel the structure of DNA at a repaired DNA replication fork by unwinding small portions of duplex DNA to prepare the fork for replisome reloading. While PriA’s helicase activity is not strictly required for cell viability in E. coli, the sequence motifs that confer helicase activity upon PriA are well-conserved among sequenced bacterial priA genes, suggesting that PriA’s duplex DNA unwinding activity confers a selective advantage upon cells. However, these helicase sequence motifs are not well-conserved among priA genes from the Deinococcus-Thermus phylum. Here, we show that PriA from a highly radiation-resistant member of that phylum, Deinococcus radiodurans, lacks the ability to hydrolyze ATP and unwind duplex DNA, thus qualifying D. radiodurans PriA as a pseudohelicase. Despite the lack of helicase activity, D. radiodurans PriA has retained the DNA binding activity expected of a typical PriA helicase, and we present evidence for a physical interaction between D. radiodurans PriA and its cognate replicative helicase, DnaB. This suggests that PriA has retained a role in replisome reloading onto repaired DNA replication forks in D. radiodurans despite its lack of helicase activity. PMID:26182205

  20. Review of rank-based procedures for multicenter clinical trials.

    PubMed

    Rashid, M Mushfiqur; McKean, Joseph W; Kloke, John D

    2013-01-01

    This article reviews nonparametric alternatives to the mixed model normal theory analysis for the analyses of multicenter clinical trials. Under a mixed model, the traditional analysis is based on maximum likelihood theory under normal errors. This analysis, though, is not robust to outliers. Robust, rank-based, Wilcoxon-type procedures are reviewed for a multicenter clinical trial for the mixed model but without the assumption of normality. These procedures retain the high efficiency of Wilcoxon methods for simple location problems and are based on a fitting criterion which is robust to outliers in response space. A simple weighting scheme can be employed so that the procedures are robust to outliers in factor (design) space as well as response space. These rank-based analyses offer a complete analysis, including estimation of fixed effects and their standard errors, and tests of linear hypotheses. Both rank-based estimates of contrasts and individual treatment effects are reviewed. We illustrate the analyses using real data from a clinical trial. PMID:24138428

  1. Remotely Sensing the Photochemical Reflectance Index (PRI)

    NASA Technical Reports Server (NTRS)

    Vanderbilt, Vern

    2015-01-01

    In remote sensing, the Photochemical Reflectance Index (PRI) provides insight into physiological processes occurring inside the leaves in a stand of plants. Developed by Gamon et al., (1990 and 1992), PRI evolved from laboratory measurements of the reflectance of individual leaves (Bilger et al.,1989). Yet in a remotely sensed image, a pixel measurement may include light from both reflecting and transmitting leaves. We conducted laboratory experiments comparing values of PRI based upon polarized reflectance and transmittance measurements of water and nutrient stressed leaves. We illuminated single detached leaves using a current controlled light source (Oriel model 66881) and measured the leaf weight using an analytical balance (Mettler model AE 260) and the light reflected and transmitted by the leaf during dry down using two Analytical Spectral Devices spectroradiometers. Polarizers on the incident and reflected light beams allowed us to divide the leaf reflectance into two parts: a polarized surface reflectance and a non-polarized 'leaf interior' reflectance. Our results underscore the importance when calculating PRI of removing the leaf surface reflection, which contains no information about physiological processes ongoing in the leaf interior. The results show that the leaf physiology information is in the leaf interior reflectance, not the leaf transmittance. Applied to a plant stand, these results suggest use of polarization measurements in sun-view directions that minimize the number of sunlit transmitting leaves in the sensor field of view.

  2. Review of advanced catheter technologies in radiation oncology brachytherapy procedures

    PubMed Central

    Zhou, Jun; Zamdborg, Leonid; Sebastian, Evelyn

    2015-01-01

    The development of new catheter and applicator technologies in recent years has significantly improved treatment accuracy, efficiency, and outcomes in brachytherapy. In this paper, we review these advances, focusing on the performance of catheter imaging and reconstruction techniques in brachytherapy procedures using magnetic resonance images and electromagnetic tracking. The accuracy of catheter reconstruction, imaging artifacts, and other notable properties of plastic and titanium applicators in gynecologic treatments are reviewed. The accuracy, noise performance, and limitations of electromagnetic tracking for catheter reconstruction are discussed. Several newly developed applicators for accelerated partial breast irradiation and gynecologic treatments are also reviewed. New hypofractionated high dose rate treatment schemes in prostate cancer and accelerated partial breast irradiation are presented. PMID:26203277

  3. Differential interference of vitamin D analogs PRI-1906, PRI-2191, and PRI-2205 with the renewal of human colon cancer cells refractory to treatment with 5-fluorouracil.

    PubMed

    Kotlarz, Agnieszka; Przybyszewska, Małgorzata; Swoboda, Paweł; Miłoszewska, Joanna; Grygorowicz, Monika Anna; Kutner, Andrzej; Markowicz, Sergiusz

    2016-04-01

    This study was aimed to determine whether hypocalcemic analogs of active forms of vitamins D modulate expression of genes related to stem-like phenotype in colon cancer cell lines HT-29 and HCT-116 undergoing renewal after the treatment with 5-fluorouracil (5-FU). Both lines express vitamin D receptor, but differ in differentiation stage and vitamin D sensitivity. Cells that resisted the 5-FU exposure were treated with synthetic analog of 1,25-dihydroxyvitamin D2 (PRI-1906) and analogs of 1,25-dihydroxyvitamin D3 (PRI-2191 and PRI-2205). Proliferative activity was more profoundly affected by vitamin D analogs in HT-29/5-FU than in HCT-116/5-FU cells. In HT-29/5-FU cells, analogs PRI-1906 and PRI-2191 downregulated the expression of genes related to survival, re-growth, and invasiveness during renewal, while PRI-2205 increased expression of genes related to differentiation only. In HCT-116/5-FU cells, PRI-2191 decreased the expression of stemness- and angiogenesis-related genes, whereas PRI-1906 augmented their expression. The effects in HCT-116/5-FU cells were observed at higher concentrations of the analogs than those used for HT-29/5-FU cells. Out of the series of analogs studied, PRI-2191 might be used to counteract the renewal of both moderately and poorly differentiated cancer cells following conventional treatment. PMID:26511971

  4. 40 CFR 155.58 - Procedures for issuing a decision on a registration review case.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Procedures for issuing a decision on a registration review case. 155.58 Section 155.58 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS REGISTRATION STANDARDS AND REGISTRATION REVIEW Registration Review Procedures § 155.58 Procedures for issuing...

  5. 20 CFR 405.215 - Procedures before a Federal reviewing official.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Procedures before a Federal reviewing... PROCESS FOR ADJUDICATING INITIAL DISABILITY CLAIMS Review of Initial Determinations by a Federal Reviewing Official § 405.215 Procedures before a Federal reviewing official. (a) General. The Federal...

  6. 20 CFR 405.401 - Procedures before the Decision Review Board-general.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Procedures before the Decision Review Board-general. 405.401 Section 405.401 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ADMINISTRATIVE REVIEW PROCESS FOR ADJUDICATING INITIAL DISABILITY CLAIMS Decision Review Board § 405.401 Procedures before the Decision Review Board—general. (a)...

  7. 40 CFR 155.58 - Procedures for issuing a decision on a registration review case.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) PESTICIDE PROGRAMS REGISTRATION STANDARDS AND REGISTRATION REVIEW Registration Review Procedures... pesticide's registration review docket the Agency's proposed decision and the bases for the decision. There... standard for registration and describe the basis for such proposed findings. (2) Identify proposed...

  8. Nursing care in the anesthetic procedure: an integrative review.

    PubMed

    Lemos, Cassiane de Santana; Peniche, Aparecida de Cassia Giani

    2016-02-01

    OBJECTIVE To search for the scientific evidence available on nursing professional actions during the anesthetic procedure. METHOD An integrative review of articles in Portuguese, English and Spanish, indexed in MEDLINE/PubMed, CINAHL, LILACS, National Cochrane, SciELO databases and the VHL portal. RESULTS Seven studies were analyzed, showing nurse anesthetists' work in countries such as the United States and parts of Europe, with the formulation of a plan for anesthesia and patient care regarding the verification of materials and intraoperative controls. The barriers to their performance involved working in conjunction with or supervised by anesthesiologists, the lack of government guidelines and policies for the legal exercise of the profession, and the conflict between nursing and the health system for maintenance of the performance in places with legislation and defined protocols for the specialty. Conclusion Despite the methodological weaknesses found, the studies indicated a wide diversity of nursing work. Furthermore, in countries absent of the specialty, like Brazil, the need to develop guidelines for care during the anesthetic procedure was observed. PMID:27007433

  9. 29 CFR 530.407 - Procedures for initiating and undertaking review.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Procedures for initiating and undertaking review. 530.407 Section 530.407 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF... Procedures for initiating and undertaking review. Any party desiring review of the decision of...

  10. 21 CFR 814.44 - Procedures for review of a PMA.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Procedures for review of a PMA. 814.44 Section 814...) MEDICAL DEVICES PREMARKET APPROVAL OF MEDICAL DEVICES FDA Action on a PMA § 814.44 Procedures for review of a PMA. (a) FDA will begin substantive review of a PMA after the PMA is accepted for filing...

  11. 16 CFR 1021.7 - Coordination of environmental review with CPSC procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... decisionmaking process. (c) Draft EISs or findings of no significant impact together with environmental... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Coordination of environmental review with... ENVIRONMENTAL REVIEW Procedures § 1021.7 Coordination of environmental review with CPSC procedures. (a)...

  12. 16 CFR 1021.7 - Coordination of environmental review with CPSC procedures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... decisionmaking process. (c) Draft EISs or findings of no significant impact together with environmental... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Coordination of environmental review with... ENVIRONMENTAL REVIEW Procedures § 1021.7 Coordination of environmental review with CPSC procedures. (a)...

  13. 16 CFR 1021.7 - Coordination of environmental review with CPSC procedures.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... decisionmaking process. (c) Draft EISs or findings of no significant impact together with environmental... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Coordination of environmental review with... ENVIRONMENTAL REVIEW Procedures § 1021.7 Coordination of environmental review with CPSC procedures. (a)...

  14. 16 CFR 1021.7 - Coordination of environmental review with CPSC procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... decisionmaking process. (c) Draft EISs or findings of no significant impact together with environmental... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Coordination of environmental review with... ENVIRONMENTAL REVIEW Procedures § 1021.7 Coordination of environmental review with CPSC procedures. (a)...

  15. 16 CFR 1021.7 - Coordination of environmental review with CPSC procedures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... decisionmaking process. (c) Draft EISs or findings of no significant impact together with environmental... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Coordination of environmental review with... ENVIRONMENTAL REVIEW Procedures § 1021.7 Coordination of environmental review with CPSC procedures. (a)...

  16. Applications of Desensitization Procedures for School-Related Problems; A Review.

    ERIC Educational Resources Information Center

    Prout, H. Thompson; Harvey, John R.

    1978-01-01

    A variety of desensitization and counterconditioning procedures have been utilized to deal with school-related problems. These procedures are reviewed with respect to applications for treating school phobia, test anxiety, and other academic anxieties. (Author)

  17. DOE EERE Standard Operating Procedure Peer Review Best Practice and Procedures

    SciTech Connect

    2009-01-18

    Objective review and advice from peers - peer review - provides managers, staff, and researchers with a powerful and effective tool for enhancing the management, relevance, effectiveness, and productivity of all of the EERE research, development

  18. 14 CFR 435.23 - Policy review requirements and procedures.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING REENTRY OF A REENTRY VEHICLE OTHER THAN A REUSABLE LAUNCH VEHICLE (RLV) Policy Review and Approval for Reentry of a Reentry Vehicle § 435.23 Policy review... apply to the policy review conducted for a license to reenter a reentry vehicle under this part....

  19. 14 CFR 435.33 - Safety review requirements and procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING REENTRY OF A REENTRY VEHICLE OTHER THAN A REUSABLE LAUNCH VEHICLE (RLV) Safety Review and Approval for Reentry of a Reentry Vehicle § 435.33 Safety review... to the safety review conducted for a license to reenter a reentry vehicle under this part....

  20. 14 CFR 435.23 - Policy review requirements and procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING REENTRY OF A REENTRY VEHICLE OTHER THAN A REUSABLE LAUNCH VEHICLE (RLV) Policy Review and Approval for Reentry of a Reentry Vehicle § 435.23 Policy review... apply to the policy review conducted for a license to reenter a reentry vehicle under this part....

  1. 14 CFR 435.23 - Policy review requirements and procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING REENTRY OF A REENTRY VEHICLE OTHER THAN A REUSABLE LAUNCH VEHICLE (RLV) Policy Review and Approval for Reentry of a Reentry Vehicle § 435.23 Policy review... apply to the policy review conducted for a license to reenter a reentry vehicle under this part....

  2. 14 CFR 435.33 - Safety review requirements and procedures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING REENTRY OF A REENTRY VEHICLE OTHER THAN A REUSABLE LAUNCH VEHICLE (RLV) Safety Review and Approval for Reentry of a Reentry Vehicle § 435.33 Safety review... to the safety review conducted for a license to reenter a reentry vehicle under this part....

  3. 14 CFR 435.23 - Policy review requirements and procedures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING REENTRY OF A REENTRY VEHICLE OTHER THAN A REUSABLE LAUNCH VEHICLE (RLV) Policy Review and Approval for Reentry of a Reentry Vehicle § 435.23 Policy review... apply to the policy review conducted for a license to reenter a reentry vehicle under this part....

  4. 14 CFR 435.33 - Safety review requirements and procedures.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING REENTRY OF A REENTRY VEHICLE OTHER THAN A REUSABLE LAUNCH VEHICLE (RLV) Safety Review and Approval for Reentry of a Reentry Vehicle § 435.33 Safety review... to the safety review conducted for a license to reenter a reentry vehicle under this part....

  5. 14 CFR 435.33 - Safety review requirements and procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING REENTRY OF A REENTRY VEHICLE OTHER THAN A REUSABLE LAUNCH VEHICLE (RLV) Safety Review and Approval for Reentry of a Reentry Vehicle § 435.33 Safety review... to the safety review conducted for a license to reenter a reentry vehicle under this part....

  6. 76 FR 38183 - Subcommittee on Procedures Review, Advisory Board on Radiation and Worker Health (ABRWH...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ... the reviews of all procedures used in the dose reconstruction process by the NIOSH Division of... Consider When Processing Claims for Construction Trade Workers''), OTIB-0054 (``Fission and Activation... of the comment- resolution process for other dose reconstruction procedures under review by...

  7. 76 FR 11483 - Subcommittee on Procedures Review, Advisory Board on Radiation and Worker Health (ABRWH...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-02

    ... the reviews of all procedures used in the dose reconstruction process by the NIOSH Division of... Processing Claims for Construction Trade Workers''), OTIB-0054 (``Fission and Activation Product Assignment... of the comment-resolution process for other dose reconstruction procedures under review by...

  8. 75 FR 28626 - Subcommittee on Procedures Review, Advisory Board on Radiation and Worker Health (ABRWH...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-21

    ... the reviews of all procedures used in the dose reconstruction process by the NIOSH Division of... Facility''), OTIB-0054 (``Fission and Activation Product Assignment for Internal Dose-Related Gross Beta...-resolution process for other dose reconstruction procedures under review by the Subcommittee. The agenda...

  9. 77 FR 40890 - Subcommittee on Procedures Review, Advisory Board on Radiation and Worker Health (ABRWH...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-11

    ... the reviews of all procedures used in the dose reconstruction process by the NIOSH Division of... Claims for Construction Trade Workers''), OTIB-0054 (``Fission and Activation Product Assignment for... comment-resolution process for other dose reconstruction procedures under review by the Subcommittee....

  10. 75 FR 10807 - Subcommittee on Procedures Reviews (SPR), Advisory Board on Radiation and Worker Health (ABRWH...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-09

    ... participating in the reviews of all procedures used in the dose reconstruction process by the NIOSH Office of... Neutron Dose at the Oak Ridge Y-12 Facility''), OTIB-0054 (``Fission and Activation Product Assignment for...-resolution process for other dose reconstruction procedures under review by the Subcommittee. ] The agenda...

  11. 75 FR 78998 - Subcommittee on Procedures Review, Advisory Board on Radiation and Worker Health (ABRWH...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... the reviews of all procedures used in the dose reconstruction process by the NIOSH Division of... Processing Claims for Construction Trade Workers''), OTIB-0054 (``Fission and Activation Product Assignment... comment- resolution process for other dose reconstruction procedures under review by the Subcommittee....

  12. 75 FR 29321 - Streamlined Procedure for Appeal Brief Review in Ex Parte Reexamination Proceedings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-25

    ... Patent and Trademark Office Streamlined Procedure for Appeal Brief Review in Ex Parte Reexamination... States Patent and Trademark Office (USPTO) is streamlining the procedure for the review of appeal briefs... whether appeal briefs filed in ex parte reexamination proceeding appeals comply with the...

  13. 34 CFR 76.400 - State procedures for reviewing an application.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false State procedures for reviewing an application. 76.400 Section 76.400 Education Office of the Secretary, Department of Education STATE-ADMINISTERED PROGRAMS How a Subgrant Is Made to an Applicant § 76.400 State procedures for reviewing an application. A...

  14. 29 CFR 502.42 - Procedures for initiating and undertaking review.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Procedures for initiating and undertaking review. 502.42 Section 502.42 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... of Administrative Law Judge's Decision § 502.42 Procedures for initiating and undertaking review....

  15. 21 CFR 814.44 - Procedures for review of a PMA.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Procedures for review of a PMA. 814.44 Section 814...) MEDICAL DEVICES PREMARKET APPROVAL OF MEDICAL DEVICES FDA Action on a PMA § 814.44 Procedures for review of a PMA. Link to an amendment published at 75 FR 16351, Apr. 1, 2010. (a) FDA will begin...

  16. 42 CFR 8.28 - Expedited procedures for review of immediate suspension.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Expedited procedures for review of immediate suspension. 8.28 Section 8.28 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Accreditation Body § 8.28 Expedited procedures for review of immediate suspension. (a) Applicability. When...

  17. 42 CFR 8.28 - Expedited procedures for review of immediate suspension.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Expedited procedures for review of immediate suspension. 8.28 Section 8.28 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Accreditation Body § 8.28 Expedited procedures for review of immediate suspension. (a) Applicability. When...

  18. 3 CFR - Modernizing Federal Infrastructure Review and Permitting Regulations, Policies, and Procedures

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 3 The President 1 2014-01-01 2014-01-01 false Modernizing Federal Infrastructure Review and Permitting Regulations, Policies, and Procedures Presidential Documents Other Presidential Documents Memorandum of May 17, 2013 Modernizing Federal Infrastructure Review and Permitting Regulations, Policies, and Procedures Memorandum for the Heads...

  19. 46 CFR Appendix C to Part 404 - Procedures for Annual Review of Base Pilotage Rates

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false Procedures for Annual Review of Base Pilotage Rates C Appendix C to Part 404 Shipping COAST GUARD (GREAT LAKES PILOTAGE), DEPARTMENT OF HOMELAND SECURITY GREAT LAKES PILOTAGE RATEMAKING Pt. 404, App. C Appendix C to Part 404—Procedures for Annual Review of...

  20. 46 CFR Appendix C to Part 404 - Procedures for Annual Review of Base Pilotage Rates

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false Procedures for Annual Review of Base Pilotage Rates C Appendix C to Part 404 Shipping COAST GUARD (GREAT LAKES PILOTAGE), DEPARTMENT OF HOMELAND SECURITY GREAT LAKES PILOTAGE RATEMAKING Pt. 404, App. C Appendix C to Part 404—Procedures for Annual Review of...

  1. 46 CFR Appendix C to Part 404 - Procedures for Annual Review of Base Pilotage Rates

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Procedures for Annual Review of Base Pilotage Rates C Appendix C to Part 404 Shipping COAST GUARD (GREAT LAKES PILOTAGE), DEPARTMENT OF HOMELAND SECURITY GREAT LAKES PILOTAGE RATEMAKING Pt. 404, App. C Appendix C to Part 404—Procedures for Annual Review of...

  2. 42 CFR 8.28 - Expedited procedures for review of immediate suspension.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Expedited procedures for review of immediate suspension. 8.28 Section 8.28 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Procedures for Review of Suspension...

  3. 42 CFR 8.28 - Expedited procedures for review of immediate suspension.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Expedited procedures for review of immediate suspension. 8.28 Section 8.28 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Procedures for Review of Suspension...

  4. 42 CFR 8.28 - Expedited procedures for review of immediate suspension.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Expedited procedures for review of immediate suspension. 8.28 Section 8.28 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Procedures for Review of Suspension...

  5. Functional interactions between polypyrimidine tract binding protein and PRI peptide ligand containing proteins.

    PubMed

    Coelho, Miguel B; Ascher, David B; Gooding, Clare; Lang, Emma; Maude, Hannah; Turner, David; Llorian, Miriam; Pires, Douglas E V; Attig, Jan; Smith, Christopher W J

    2016-08-15

    Polypyrimidine tract binding protein (PTBP1) is a heterogeneous nuclear ribonucleoprotein (hnRNP) that plays roles in most stages of the life-cycle of pre-mRNA and mRNAs in the nucleus and cytoplasm. PTBP1 has four RNA binding domains of the RNA recognition motif (RRM) family, each of which can bind to pyrimidine motifs. In addition, RRM2 can interact via its dorsal surface with proteins containing short peptide ligands known as PTB RRM2 interacting (PRI) motifs, originally found in the protein Raver1. Here we review our recent progress in understanding the interactions of PTB with RNA and with various proteins containing PRI ligands. PMID:27528752

  6. 23 CFR 230.409 - Contract compliance review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... on previous PR-1391's (23 CFR part 230, subpart A, appendix C) Review Reports and Hometown Plan...) No compliance review shall be conducted that is based on a home office work force of less than 15... an area work force (outside of areawide plan coverage), the Compliance Specialist shall define...

  7. 23 CFR 230.409 - Contract compliance review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... on previous PR-1391's (23 CFR part 230, subpart A, appendix C) Review Reports and Hometown Plan...) No compliance review shall be conducted that is based on a home office work force of less than 15... an area work force (outside of areawide plan coverage), the Compliance Specialist shall define...

  8. 42 CFR 405.1834 - CMS reviewing official procedure.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... reviewing official may immediately review a ruling, authorizing discovery or disclosure of a matter, where... discovery or disclosure in accordance with paragraph (b)(3) of this section must— (i) Be made as soon as... intermediary hearing officer(s) taking the actions required on remand and issuing a new intermediary...

  9. 19 CFR 145.22 - Procedures for obtaining administrative review.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Customs officers are authorized to review mail entries (see 39 CFR 10.5), the postmaster may send the mail... statement of his objections. The postmaster will forward the mail entry together with the addressee's... SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) MAIL IMPORTATIONS Administrative Review of Mail...

  10. 19 CFR 145.22 - Procedures for obtaining administrative review.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... the ports at which CBP officers are authorized to review mail entries (see 39 CFR 10.5), the... postmaster with a written statement of his objections. The postmaster will forward the mail entry together... SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) MAIL IMPORTATIONS Administrative Review of Mail...

  11. 19 CFR 145.22 - Procedures for obtaining administrative review.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... the ports at which CBP officers are authorized to review mail entries (see 39 CFR 10.5), the... postmaster with a written statement of his objections. The postmaster will forward the mail entry together... SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) MAIL IMPORTATIONS Administrative Review of Mail...

  12. 19 CFR 145.22 - Procedures for obtaining administrative review.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... the ports at which CBP officers are authorized to review mail entries (see 39 CFR 10.5), the... postmaster with a written statement of his objections. The postmaster will forward the mail entry together... SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) MAIL IMPORTATIONS Administrative Review of Mail...

  13. 19 CFR 145.22 - Procedures for obtaining administrative review.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... the ports at which CBP officers are authorized to review mail entries (see 39 CFR 10.5), the... postmaster with a written statement of his objections. The postmaster will forward the mail entry together... SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) MAIL IMPORTATIONS Administrative Review of Mail...

  14. 33 CFR 51.9 - Discharge review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... classified documents, are made available to the applicant and applicant's representative prior to the hearing date (or review date if no hearing is requested). The DRB shall not consider a classified document in the review of a discharge unless a summary of, or extract from, the document (deleting all...

  15. 33 CFR 51.9 - Discharge review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... classified documents, are made available to the applicant and applicant's representative prior to the hearing date (or review date if no hearing is requested). The DRB shall not consider a classified document in the review of a discharge unless a summary of, or extract from, the document (deleting all...

  16. 33 CFR 51.9 - Discharge review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., applicants or their representatives may obtain copies of military records by submitting a Standard Form 180... review of discharge by submitting DD Form 293, Application for Review of Discharge or Separation from the... of the discharge. The application form can be obtained, along with explanatory matter,...

  17. 23 CFR 230.409 - Contract compliance review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... action plan but the actions do not result in the necessary changes, the corrective action plan shall be... plan or failure of corrective actions to result in necessary changes. (i) Followup reviews. (1) A... on previous PR-1391's (23 CFR part 230, subpart A, appendix C) Review Reports and Hometown...

  18. 23 CFR 230.409 - Contract compliance review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... action plan but the actions do not result in the necessary changes, the corrective action plan shall be... plan or failure of corrective actions to result in necessary changes. (i) Followup reviews. (1) A... on previous PR-1391's (23 CFR part 230, subpart A, appendix C) Review Reports and Hometown...

  19. Hypnosis for Acute Procedural Pain: A Critical Review.

    PubMed

    Kendrick, Cassie; Sliwinski, Jim; Yu, Yimin; Johnson, Aimee; Fisher, William; Kekecs, Zoltán; Elkins, Gary

    2016-01-01

    Clinical evidence for the effectiveness of hypnosis in the treatment of acute procedural pain was critically evaluated based on reports from randomized controlled clinical trials (RCTs). Results from the 29 RCTs meeting inclusion criteria suggest that hypnosis decreases pain compared to standard care and attention control groups and that it is at least as effective as comparable adjunct psychological or behavioral therapies. In addition, applying hypnosis in multiple sessions prior to the day of the procedure produced the highest percentage of significant results. Hypnosis was most effective in minor surgical procedures. However, interpretations are limited by considerable risk of bias. Further studies using minimally effective control conditions and systematic control of intervention dose and timing are required to strengthen conclusions. PMID:26599994

  20. Transcatheter Renal Interventions: A Review of Established and Emerging Procedures

    PubMed Central

    Minocha, Jeet; Parvinian, Ahmad; Bui, James T; Knuttinen, Martha Grace; Ray, Charles E; Gaba, Ron C

    2015-01-01

    Catheter-based interventions play an important role in the multidisciplinary management of renal pathology. The array of procedures available to interventional radiologists (IRs) includes established techniques such as angioplasty, stenting, embolization, thrombolysis, and thrombectomy for treatment of renovascular disease, as well as embolization of renal neoplasms and emerging therapies such as transcatheter renal artery sympathectomy for treatment of resistant hypertension. Here, we present an overview of these minimally invasive therapies, with an emphasis on interventional technique and clinical outcomes of the procedure. PMID:25806140

  1. [Review As You Go: Oklahoma City Public Schools' Plan Using Saxon's Procedures.

    ERIC Educational Resources Information Center

    Hartzler, Stan

    This document consists of three related items. The first brief paper describes the components of a cumulative daily review program and its origins, rationale, and outcomes. The review-as-you-go (RAYG) format entails planning cumulative examinations and providing review problems each day. The procedure once was routinely used; today it is…

  2. 42 CFR 476.160 - General quality of care review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false General quality of care review procedures. 476.160 Section 476.160 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) QUALITY IMPROVEMENT ORGANIZATIONS UTILIZATION AND QUALITY CONTROL REVIEW Review Responsibilities of Utilization and...

  3. 42 CFR 476.160 - General quality of care review procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false General quality of care review procedures. 476.160 Section 476.160 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) QUALITY IMPROVEMENT ORGANIZATIONS QUALITY IMPROVEMENT ORGANIZATION REVIEW Review Responsibilities of Quality...

  4. 32 CFR 861.5 - DOD Commercial Airlift Review Board procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false DOD Commercial Airlift Review Board procedures. 861.5 Section 861.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE AIRCRAFT DEPARTMENT OF DEFENSE COMMERCIAL AIR TRANSPORTATION QUALITY AND SAFETY REVIEW PROGRAM § 861.5 DOD Commercial Airlift Review Board...

  5. 32 CFR 861.5 - DOD Commercial Airlift Review Board procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false DOD Commercial Airlift Review Board procedures. 861.5 Section 861.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE AIRCRAFT DEPARTMENT OF DEFENSE COMMERCIAL AIR TRANSPORTATION QUALITY AND SAFETY REVIEW PROGRAM § 861.5 DOD Commercial Airlift Review Board...

  6. Explaining the variability of Photochemical Reflectance Index (PRI): deconvolution of variability related to Light Use Efficiency and Canopy attributes.

    NASA Astrophysics Data System (ADS)

    Merlier, Elodie; Hmimina, Gabriel; Dufrêne, Eric; Soudani, Kamel

    2014-05-01

    . 1992. A narrow-waveband spectral index that tracks diurnal changes in photosynthetic efficiency. Remote Sensing of Environment 41, 35-44. Garbulsky MF, Peñuelas J, Gamon J, Inoue Y, Filella I. 2011. The photochemical reflectance index (PRI) and the remote sensing of leaf, canopy and ecosystem radiation use efficiencies: A review and meta-analysis. Remote Sensing of Environment 115, 281-297. Hilker T, Coops NC, Hall FG, Black TA, Wulder MA, Nesic Z, Krishnan P. 2008. Separating physiologically and directionally induced changes in PRI using BRDF models. Remote Sensing of Environment 112, 2777-2788. Hmimina G, Dufrêne E, Soudani K. 2014. Relationship between PRI and leaf ecophysiological and biochemical parameters under two different water statuses: toward a rapid and efficient correction method using real-time measurements. Plant, Cell & Environment 37, 2, 473-487. Nakaji T, Oguma H, Fujinuma Y. 2006. Seasonal changes in the relationship between photochemical reflectance index and photosynthetic light use efficiency of Japanese larch needles. International Journal of Remote Sensing 27, 493-509. Rahimzadeh-Bajgiran P, Munehiro M, Omasa K. 2012. Relationships between the photochemical reflectance index (PRI) and chlorophyll fluorescence parameters and plant pigment indices at different leaf growth stages. Photosynthesis Research 113, 261-271.

  7. Development of electrical test procedures for qualification of spacecraft against EID. Volume 2: Review and specification of test procedures

    NASA Technical Reports Server (NTRS)

    Wilkenfeld, J. M.; Harlacher, B. L.; Mathews, D.

    1982-01-01

    A combined experimental and analytical program to develop system electrical test procedures for the qualification of spacecraft against damage produced by space-electron-induced discharges (EID) occurring on spacecraft dielectric outer surfaces is described. A review and critical evaluation of possible approaches to qualify spacecraft against space electron-induced discharges (EID) is presented. A variety of possible schemes to simulate EID electromagnetic effects produced in spacecraft was studied. These techniques form the principal element of a provisional, recommended set of test procedures for the EID qualification spacecraft. Significant gaps in our knowledge about EID which impact the final specification of an electrical test to qualify spacecraft against EID are also identified.

  8. 44 CFR 8.4 - Mandatory declassification review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... imposed in accordance with the provisions of 44 CFR part 5, subpart C. (g) The following procedures shall... citizen or permanent resident alien, a Federal agency or a State or local government. (b) Requests for... Security Oversight Committee (ISOC). Representation on the FEMA ISOC shall include the Director of...

  9. 32 CFR 70.8 - Discharge review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Information Act (32 CFR part 286) or Privacy Act (32 CFR part 286a) after the DD Form 293 has been submitted..., The Pentagon, Washington, DC 20310. (2) Timing. A motion or request for review must be made within...

  10. Diagnostic procedures for autoimmune vesiculobullous diseases: A review

    PubMed Central

    Rastogi, Varun; Sharma, Rachna; Misra, Satya Ranjan; Yadav, Lalita

    2014-01-01

    Oral soft tissues are affected by numerous pathologic conditions of variable etiology and hence their appropriate management relies on their accurate diagnosis. Clinical identification of intact vesicle and bulla in the oral cavity is really a challenge due to the regular irritation and the friable nature of oral mucosa. Rupture of these lesions leads to erosions or ulcerations on the surface, hence making the diagnosis of vesiculobullous (VB) lesions is even more difficult due to the fact that the differential diagnosis along with VB lesions will also include ulcerative, immunological-mediated diseases, and neoplasms and systemic diseases. Hence, knowledge of the clinical presentation of these disorders and the relevant diagnostic procedures is important not just for dermatologists, but also for general practitioners and dentists. In this article, the various procedures have been explained that can be used for the diagnostic purpose of VB lesions. PMID:25948994

  11. EUS-Guided Vascular Procedures: A Literature Review

    PubMed Central

    Kujundzic, Milan

    2013-01-01

    Endoscopic ultrasound (EUS) is continuously stepping into the therapeutic arena, simultaneously evolving in different directions, such as the management of pancreatic and biliary diseases, celiac neurolysis, delivering local intratumoral therapy, and EUS-guided endosurgery. EUS-guided vascular procedures are also challenging, considering the variety of vascular pathology, proximity of the vascular structures to the GI tract wall, high resolution, and real-time guidance offering an attractive access route and precise delivery of the intervention. The literature on vascular therapeutic EUS demonstrates techniques for the management of upper GI variceal and nonvariceal bleeding, pseudoaneurysms, and coiling and embolization procedures, as well as the creation of intrahepatic portosystemic shunts. The paucity of studies, diversity of study designs, and the number of animal model studies hamper a systematic approach to the conclusion and decision making important to clinicians and healthcare policy makers. Nevertheless, theoretical benefits and findings up to date concerning technical feasibility, efficacy, and safety of the procedures drive further research and development in this rather young therapeutic arena. PMID:23737766

  12. A short review of basic head and neck interventional procedures in a general radiology department

    PubMed Central

    Yuen, H.Y.; Lee, Y.Y.P.; Bhatia, K.

    2013-01-01

    Abstract Image-guided interventional procedures provide a safe way to diagnose and treat a variety of head and neck abnormalities. The procedure time is usually short, and most procedures can be performed on an outpatient basis. Knowledge about strengths and weaknesses, efficacy, potential complications, and pitfalls of these procedures allows the best treatment to be chosen for a particular lesion type. This review discusses some of the commonly performed interventional radiology procedures in a general radiology department in the management of patients with neoplastic diseases in the head and neck region. PMID:24334514

  13. 42 CFR 431.980 - Eligibility review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... cases in States that do not stratify the universe, as specified in § 431.978(d)(3)(ii) of this subpart... plan during the month under review. (vi) Elements of eligibility in which State policy allows for self-declaration or self-certification are considered to be verified with a self-declaration or...

  14. 32 CFR 70.8 - Discharge review procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Information Act (32 CFR part 286) or Privacy Act (32 CFR part 286a) after the DD Form 293 has been submitted... Administration, or by writing to: DA Military Review Boards Agency, Attention: SFBA (Reading Room), Room 1E520... sentence incorporated. Because it is to the applicant's benefit to bring such issues to the DRB's...

  15. 28 CFR 50.6 - Antitrust Division business review procedure.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., which may involve either domestic or foreign commerce. 3. The Division may, in its discretion, refuse to... U.S.C. 18A, and the regulations promulgated thereunder, 16 CFR, part 801. 8. After review of a... nature of action taken by the Division upon the request. (e) This paragraph reflects a...

  16. 32 CFR 70.8 - Discharge review procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Information Act (32 CFR part 286) or Privacy Act (32 CFR part 286a) after the DD Form 293 has been submitted..., The Pentagon, Washington, DC 20310. (2) Timing. A motion or request for review must be made within 15... except: (i) When the only previous consideration of the case was on the motion of the DRB; (ii) When...

  17. 32 CFR 70.8 - Discharge review procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Information Act (32 CFR part 286) or Privacy Act (32 CFR part 286a) after the DD Form 293 has been submitted..., The Pentagon, Washington, DC 20310. (2) Timing. A motion or request for review must be made within 15... except: (i) When the only previous consideration of the case was on the motion of the DRB; (ii) When...

  18. 48 CFR 1552.237-70 - Contract publication review procedures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... publish, in a scientific journal, material resulting directly or indirectly from work performed under this... in a journal article which has not been subjected to EPA review: “Although the research described in....” (3) Following publication of the journal article, the Contractor shall submit five copies of...

  19. 42 CFR 423.1080 - Procedures before the Departmental Appeals Board on review.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Procedures before the Departmental Appeals Board on review. 423.1080 Section 423.1080 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF... 423.1016....

  20. 78 FR 64234 - 30-Day Notice of Proposed Information Collection: Environmental Review Procedures for Entities...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-28

    ... Entities Assuming HUD Environmental Responsibilities AGENCY: Office of the Chief Information Officer, HUD... Responsibilities. OMB Approval Number: 2506-0087. Type of Request: Revision of a currently approved collection..., ``Environmental Review Procedures for Entities Assuming HUD Environmental Responsibilities'' requires units...

  1. Limiting excessive postoperative blood transfusion after cardiac procedures. A review.

    PubMed Central

    Ferraris, V A; Ferraris, S P

    1995-01-01

    Analysis of blood product use after cardiac operations reveals that a few patients (< or = 20%) consume the majority of blood products (> 80%). The risk factors that predispose a minority of patients to excessive blood use include patient-related factors, transfusion practices, drug-related causes, and procedure-related factors. Multivariate studies suggest that patient age and red blood cell volume are independent patient-related variables that predict excessive blood product transfusion after cardiac procedures. Other factors include preoperative aspirin ingestion, type of operation, over- or underutilization of heparin during cardiopulmonary bypass, failure to correct hypothermia after cardiopulmonary bypass, and physician overtransfusion. A survey of the currently available blood conservation techniques reveals 5 that stand out as reliable methods: 1) high-dose aprotinin therapy, 2) preoperative erythropoietin therapy when time permits adequate dosage before operation, 3) hemodilution by harvest of whole blood immediately before cardiopulmonary bypass, 4) autologous predonation of blood, and 5) salvage of oxygenator blood after cardiopulmonary bypass. Other methods, such as the use of epsilon-aminocaproic acid or desmopressin, cell saving devices, reinfusion of shed mediastinal blood, and hemofiltration have been reported to be less reliable and may even be harmful in some high-risk patients. Consideration of the available data allows formulation of a 4-pronged plan for limiting excessive blood transfusion after surgery: 1) recognize the causes of excessive transfusion, including the importance of red blood cell volume, type of procedure being performed, preoperative aspirin ingestion, etc.; 2) establish a quality management program, including a survey of transfusion practices that emphasizes physician education and availability of real-time laboratory testing to guide transfusion therapy; 3) adopt a multimodal approach using institution-proven techniques; and

  2. Tooth-bleaching procedures and their controversial effects: A literature review

    PubMed Central

    Alqahtani, Mohammed Q.

    2014-01-01

    Aim This review article will help clinicians improve their understanding of the history of bleaching procedures, bleaching types, components, mechanisms, and their effects on soft tissue, tooth structures, resin composite, and bonding. Methods The controversial issues about bleaching procedures and their effects are reviewed. Additionally, the consequences of pre- and post-bleaching on the bonding potential of composite resin restorations to tooth structure are discussed. Conclusion The overall goal of the paper is to help reduce risks for patients. PMID:25408594

  3. 76 FR 54775 - Subcommittee on Procedures Review, Advisory Board on Radiation and Worker Health (ABRWH...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-02

    ... all procedures used in the dose reconstruction process by the NIOSH Division of Compensation Analysis... Construction Trade Workers''), OTIB-0054 (``Fission and Activation Product Assignment for Internal Dose-Related... process for other dose reconstruction procedures under review by the Subcommittee. The agenda is...

  4. 29 CFR 580.13 - Procedures for appeals to the Administrative Review Board.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Procedures for appeals to the Administrative Review Board. 580.13 Section 580.13 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS CIVIL MONEY PENALTIES-PROCEDURES FOR ASSESSING AND CONTESTING...

  5. 34 CFR 303.342 - Procedures for IFSP development, review, and evaluation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... development, review, and evaluation. (a) Meeting to develop initial IFSP—timelines. For a child referred to... 34 Education 2 2012-07-01 2012-07-01 false Procedures for IFSP development, review, and evaluation... PROGRAM FOR INFANTS AND TODDLERS WITH DISABILITIES Child Find, Evaluations and Assessments,...

  6. 34 CFR 303.342 - Procedures for IFSP development, review, and evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... development, review, and evaluation. (a) Meeting to develop initial IFSP—timelines. For a child who has been... 34 Education 2 2010-07-01 2010-07-01 false Procedures for IFSP development, review, and evaluation... child and the child's family must be conducted every six months, or more frequently if...

  7. 34 CFR 303.342 - Procedures for IFSP development, review, and evaluation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... development, review, and evaluation. (a) Meeting to develop initial IFSP—timelines. For a child referred to... 34 Education 2 2013-07-01 2013-07-01 false Procedures for IFSP development, review, and evaluation... PROGRAM FOR INFANTS AND TODDLERS WITH DISABILITIES Child Find, Evaluations and Assessments,...

  8. 34 CFR 303.342 - Procedures for IFSP development, review, and evaluation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... development, review, and evaluation. (a) Meeting to develop initial IFSP—timelines. For a child who has been... 34 Education 2 2011-07-01 2010-07-01 true Procedures for IFSP development, review, and evaluation... child and the child's family must be conducted every six months, or more frequently if...

  9. 34 CFR 303.342 - Procedures for IFSP development, review, and evaluation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... development, review, and evaluation. (a) Meeting to develop initial IFSP—timelines. For a child referred to... 34 Education 2 2014-07-01 2013-07-01 true Procedures for IFSP development, review, and evaluation... PROGRAM FOR INFANTS AND TODDLERS WITH DISABILITIES Child Find, Evaluations and Assessments,...

  10. 15 CFR Supplement No. 9 to Part 748 - End-User Review Committee Procedures

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... No. Supplement No. 9 to Part 748 Commerce and Foreign Trade Regulations Relating to Commerce and... No. 9 to Part 748—End-User Review Committee Procedures (1) The End-User Review Committee (ERC... the list of validated end-users and associated eligible items set forth in Supplement No. 7 to...

  11. 15 CFR Supplement No. 9 to Part 748 - End-User Review Committee Procedures

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... No. Supplement No. 9 to Part 748 Commerce and Foreign Trade Regulations Relating to Commerce and... No. 9 to Part 748—End-User Review Committee Procedures (1) The End-User Review Committee (ERC... the list of validated end-users and associated eligible items set forth in supplement No. 7 to...

  12. Review of numerical procedures for computational surface thermochemistry

    NASA Technical Reports Server (NTRS)

    Milos, Frank S.; Rasky, Daniel J.

    1994-01-01

    Models and equations for surface thermochemistry and near-surface thermophysics of aerodynamically heated thermal protection materials are reviewed, with particular emphasis on computational boundary conditions for surface mass and energy transfer. The surface energy and mass balances, coupled with an appropriate ablation or surface catalysis model, provide complete thermochemical boundary conditions for a true multidisciplinary solution of the fully coupled fluid-dynamics/solid mechanics problem. Practical approximate solutions can be obtained by using a detailed model with full thermophysics for either the solid or fluid phase and a semianalytic method for the other half of the problem. A significant increase in the state-of-the-art in aerothermal computational fluid dynamics is possible by uniting computational fluid dynamic (CFD) methodology with surface thermochemistry boundary conditions and the heat-balance-integral method.

  13. Procedural Learning and Memory Rehabilitation in Korsakoff's Syndrome - a Review of the Literature.

    PubMed

    Oudman, Erik; Nijboer, Tanja C W; Postma, Albert; Wijnia, Jan W; Van der Stigchel, Stefan

    2015-06-01

    Korsakoff's syndrome (KS) is a chronic neuropsychiatric disorder caused by alcohol abuse and thiamine deficiency. Patients with KS show restricted autonomy due to their severe declarative amnesia and executive disorders. Recently, it has been suggested that procedural learning and memory are relatively preserved in KS and can effectively support autonomy in KS. In the present review we describe the available evidence on procedural learning and memory in KS and highlight advances in memory rehabilitation that have been demonstrated to support procedural memory. The specific purpose of this review was to increase insights in the available tools for successful memory rehabilitation and give suggestions how to apply these tools in clinical practice to increase procedural learning in KS. Current evidence suggests that when memory rehabilitation is adjusted to the specific needs of KS patients, this will increase their ability to learn procedures and their typically compromised autonomy gets enhanced. PMID:26047664

  14. Finding the SurPriSe: A Case Study of a Faculty Learning Community

    ERIC Educational Resources Information Center

    Michel, Roberta M.

    2014-01-01

    This article details a faculty learning community (FLC) that started in 2009 on the campus of a Midwestern University and has evolved into an interdisciplinary research, teaching and social community of practice and learning called SurPriSe. SurPriSe is an acronym that reflects the interest area of the FLC; Sur for surveillance, Pri for privacy,…

  15. A Review of Clinical Data for Currently Approved Hysteroscopic Sterilization Procedures

    PubMed Central

    Basinski, Cindy M

    2010-01-01

    Two hysteroscopic permanent sterilization procedures are approved for use in the United States: Essure® Permanent Birth Control System (Conceptus Incorporated, Mountain View, CA) and Adiana® Permanent Contraception (Hologic, Inc., Bedford, MA). This review compares the clinical trial data for these procedures. A notable difference is the resultant clinical pregnancy risk. The clinical trials for the Essure procedure have reported no pregnancies in 643 relying women in the 9 years since initiation of the studies. The clinical trial for the Adiana procedure has reported 12 pregnancies in 570 relying women in nearly 5 years of collected data. Other clinical outcome parameters concerning Essure and Adiana are examined in this review. PMID:21364861

  16. The policy & procedure manual: development of a computer-assisted process for review.

    PubMed

    Crawford, N; Norris, J R; Ferguson-Paré, M L

    1993-01-01

    This article documents the successful development of a computer-assisted process for systematic review of nursing policies and procedures at The Queen Elizabeth Hospital, Toronto, Ontario. Through broad staff input, policies and procedures are research-based yet grounded in the reality of the facility's nursing practice. Client-related standards are written as measurable, realistic statements of desired client outcomes, and as such are standards for client care. Policies and procedures have been rated according to the Canadian Council on Health Facilities Accreditation criteria (client centered, high risk, high volume, problem prone, interservice, outcome-related), so that important policies are easily identified to provide focus for quality assurance activities. The review process is structured so that over the course of a year, all policies are circulated for review by all levels of nursing staff. PMID:8347653

  17. STS-34 crewmembers review IFM procedures on JSC's CCT mockup middeck

    NASA Technical Reports Server (NTRS)

    1989-01-01

    STS-34 crewmembers review inflight maintenance (IFM) procedures on the middeck of JSC's crew compartment trainer (CCT) located in the Mockup and Integration Laboratory (MAIL) Bldg 9A. IFM trainer, holding cable, discusses procedures with Mission Specialist (MS) Ellen S. Baker (center) and Pilot Michael J. McCulley. An open stowage locker appears in front of the group. Visible on the mockup's middeck are forward and aft stowage lockers, the airlock hatch, and the starboard wall mounted sleep restraints.

  18. Impact of 3D Rotational Angiography on Liver Embolization Procedures: Review of Technique and Applications

    SciTech Connect

    Lucatelli, Pierleone Corona, Mario Argirò, Renato Anzidei, Michele; Vallati, Giulio; Fanelli, Fabrizio Bezzi, Mario Catalano, Carlo

    2015-06-15

    In the last years, the interest into interventional applications of C-arm cone-beam CT (CBCT) progressively raised, widening its clinical application from the original field of interventional neuroradiology to the field of peripheral procedures. Liver embolization procedures, due to their complexity and potential treatment-related life-threatening complications, represent one of the main clinical applications of this novel angiographic technique. CBCT has been demonstrated to render procedures safer and technically easier, and to predict outcome as well as to avoid major complications in different treatment scenarios (trans-arterial embolization, trans-arterial chemoembolization, selective internal radiation therapy, percutaneous portal vein embolization). This review summarizes all technical, dosimetric and procedural aspects of CBCT techniques, underlying all its potential clinical advantages in the field of liver embolization procedures. Moreover, the paper provides all the instructions to obtain the best diagnostic performance out of this novel angiographic technique.

  19. Ocular adverse effects after facial cosmetic procedures: a review of case reports.

    PubMed

    Ricci, Lucas H; Navajas, Samia V; Carneiro, Paula R; Söderberg, Stephanie A; Ferraz, Caroline A

    2015-06-01

    To review indexed literature concerning adverse ocular effects of the most common aesthetic facial procedures (light-emitting therapy, dermal fillers injection, and botulinum toxin). Literature search using three online databases - PubMed, SciELO, and Capes - selecting case reports, series of cases and reviews, with no language restriction, published in a period of the last twenty years (1995-2015). After reviewing 48 case reports and most recent reviews, the authors found the most common ocular adverse effects of dermal fillers were related to vascular occlusion; light-emitting therapy was associated with pigmented tissue damage leading to anterior uveitis and iris atrophy, and ptosis presented the higher relative risk associated with botulinum toxin. Even though ocular adverse effects are not very frequent, some of them can lead to permanent ocular dysfunction and visual impairment. Professionals involved in cosmetic procedures should be aware of the risks. PMID:25790150

  20. Protection of human subjects: categories of research that may be reviewed by the Institutional Review Board (IRB) through an expedited review procedure--FDA. Notice.

    PubMed

    1998-11-01

    On November 10, 1997, the Food and Drug Administration (FDA), in consultation with the Office for Protection from Research Risks (OPRR) at the National Institutes of Health, requested written comments relating to the proposed republication of the list that identifies certain research activities involving human subjects that may be reviewed by the Institutional Review Board (IRB) through the expedited review procedure authorized in 21 CFR 56.110. The comment period closed on March 10, 1998. FDA and OPRR received a combined total of 108 comments. After a review of the comments, FDA and OPRR are now simultaneously publishing identical revised lists of categories of research activities that may be reviewed by the IRB through the expedited review procedure. PMID:10187395

  1. Improving the review of standard operating procedures: a novel electronic system for compounding pharmacies.

    PubMed

    Brensel, Robert; Brensel, Scott; Ng, Amy

    2013-01-01

    Since the New England Compounding Center disaster in 2012, the importance of following correct procedures during every phase of customized pharmacy has been a focus of governmental interest and action as well as public scrutiny. Many pharmacies rely on the rote review of standard operating procedures to ensure that staff members understand and follow protocols that ensure the safety and potency of all compounds prepared, but that approach to continuing education can be cumbersome and needlessly time-consuming. In addition, documenting and retrieving evidence of employee competence can be difficult. In this article, we describe our use of online technology to improve our methods of educating staff about the full range of standard operating procedures that must be followed in our pharmacy. The system we devised and implemented has proven to be effective, easy to update and maintain, very inexpensive, and user friendly. Its use has reduced the time previously required for a read-over review of standard operating procedures from 30 or 40 minutes to 5 or 10 minutes in weekly staff meetings, and we can now easily document and access proof of employees' comprehension of that content. It is our hope that other small compounding pharmacies will also find this system of online standard operating procedure review helpful. PMID:24579296

  2. 29 CFR 501.42 - Procedures for initiating and undertaking review.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Procedures for initiating and undertaking review. 501.42 Section 501.42 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS ENFORCEMENT OF CONTRACTUAL OBLIGATIONS FOR TEMPORARY ALIEN AGRICULTURAL WORKERS ADMITTED...

  3. 29 CFR 501.42 - Procedures for initiating and undertaking review.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Procedures for initiating and undertaking review. 501.42 Section 501.42 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS ENFORCEMENT OF CONTRACTUAL OBLIGATIONS FOR TEMPORARY ALIEN AGRICULTURAL WORKERS ADMITTED...

  4. Behavioristic Procedures in the Treatment of Autistic Children: A Review of the Literature.

    ERIC Educational Resources Information Center

    Akiyama, Robert M.

    Children with infantile autism display characteristics and behaviors that severely limit their growth and functioning on many levels. Research is reviewed in which principles of operant conditioning are implemented in procedures designed to investigate and/or modify the autistic child's behavior in the following areas: (a) social interaction, (b)…

  5. 78 FR 78965 - Subcommittee on Procedures Review, Advisory Board on Radiation and Worker Health (ABRWH...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... in the dose reconstruction process by the NIOSH Division of Compensation Analysis and Support (DCAS...''), OTIB 0054 (``Fission and Activation Product Assignment for Internal Dose-Related Gross Beta and Gross... of the comment- resolution process for other dose reconstruction procedures under review by...

  6. 78 FR 78963 - Subcommittee on Procedures Review, Advisory Board on Radiation and Worker Health (ABRWH...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... in the dose reconstruction process by the NIOSH Division of Compensation Analysis and Support (DCAS...''), OTIB 0054 (``Fission and Activation Product Assignment for Internal Dose-Related Gross Beta and Gross... of the comment- resolution process for other dose reconstruction procedures under review by...

  7. 78 FR 38346 - Subcommittee on Procedures Review, Advisory Board on Radiation and Worker Health (ABRWH...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Subcommittee on Procedures Review, Advisory Board on Radiation and Worker Health (ABRWH), National Institute for Occupational Safety and Health (NIOSH) In accordance with section 10(a)(2) of...

  8. 78 FR 62635 - Subcommittee on Procedures Review, Advisory Board on Radiation and Worker Health (ABRWH...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Subcommittee on Procedures Review, Advisory Board on Radiation and Worker Health (ABRWH), National Institute for Occupational Safety and Health (NIOSH) In accordance with section 10(a)(2) of...

  9. 75 FR 58408 - Subcommittee on Procedures Review, Advisory Board on Radiation and Worker Health (ABRWH...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... in the reviews of all procedures used in the dose reconstruction process by the NIOSH Division of... (``Fission and Activation Product Assignment for Internal Dose-Related Gross Beta and Gross Gamma Analyses... that Worked Uranium and Thorium Metals''); and a continuation of the comment-resolution process...

  10. 77 FR 15761 - Subcommittee on Procedures Review, Advisory Board on Radiation and Worker Health (ABRWH...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Subcommittee on Procedures Review, Advisory Board on Radiation and Worker Health (ABRWH), National Institute for Occupational Safety and Health (NIOSH) In accordance with section 10(a)(2) of...

  11. 78 FR 22490 - Administrative Practice and Procedure; Postal Service; Review of Price Cap Rules

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-16

    .... Regulatory History 72 FR 5230, February 5, 2007 72 FR 29284, May 25, 2007 72 FR 33261, June 15, 2007 72 FR 50744, September 4, 2007 72 FR 63622, November 9, 2007 SUPPLEMENTARY INFORMATION: Table of Contents I... 39 CFR Part 3010 Administrative Practice and Procedure; Postal Service; Review of Price Cap...

  12. 75 FR 50750 - Streamlined Procedure for Appeal Brief Review in Inter Partes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-17

    ... United States Patent and Trademark Office Streamlined Procedure for Appeal Brief Review in Inter Partes... appeal briefs filed in inter partes reexamination proceeding appeals to increase the efficiency of the... determining whether appeal briefs filed in inter partes reexamination proceedings (i.e., appellant's...

  13. 42 CFR 422.1080 - Procedures before the Departmental Appeals Board on review.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Procedures before the Departmental Appeals Board on review. 422.1080 Section 422.1080 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF.... Copies of any brief or other written statement must be sent in accordance with 422.1016....

  14. 24 CFR 55.10 - Environmental review procedures under 24 CFR parts 50 and 58.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Floodplain Management § 55.10 Environmental review procedures under 24 CFR parts 50 and 58. (a) Where an... subject to 24 CFR part 58) of proposed actions in a floodplain. (b) The categorical exclusion of certain... under 24 CFR parts 50 and 58. 55.10 Section 55.10 Housing and Urban Development Office of the...

  15. 24 CFR 55.10 - Environmental review procedures under 24 CFR parts 50 and 58.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Floodplain Management § 55.10 Environmental review procedures under 24 CFR parts 50 and 58. (a) Where an... subject to 24 CFR part 58) of proposed actions in a floodplain. (b) The categorical exclusion of certain... under 24 CFR parts 50 and 58. 55.10 Section 55.10 Housing and Urban Development Office of the...

  16. 24 CFR 55.10 - Environmental review procedures under 24 CFR parts 50 and 58.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Floodplain Management § 55.10 Environmental review procedures under 24 CFR parts 50 and 58. (a) Where an... subject to 24 CFR part 58) of proposed actions in a floodplain. (b) The categorical exclusion of certain... under 24 CFR parts 50 and 58. 55.10 Section 55.10 Housing and Urban Development Office of the...

  17. 24 CFR 55.10 - Environmental review procedures under 24 CFR parts 50 and 58.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Floodplain Management § 55.10 Environmental review procedures under 24 CFR parts 50 and 58. (a) Where an... subject to 24 CFR part 58) of proposed actions in a floodplain. (b) The categorical exclusion of certain... under 24 CFR parts 50 and 58. 55.10 Section 55.10 Housing and Urban Development Office of the...

  18. 42 CFR 433.120 - Procedures for reduction of FFP after reapproval review.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Procedures for reduction of FFP after reapproval review. 433.120 Section 433.120 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STATE FISCAL ADMINISTRATION Mechanized Claims Processing and Information...

  19. 23 CFR 200.11 - Procedures for processing Title VI reviews.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... appropriate action in accordance with 49 CFR. ... 23 Highways 1 2011-04-01 2011-04-01 false Procedures for processing Title VI reviews. 200.11 Section 200.11 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE...

  20. 23 CFR 200.11 - Procedures for processing Title VI reviews.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... appropriate action in accordance with 49 CFR. ... 23 Highways 1 2012-04-01 2012-04-01 false Procedures for processing Title VI reviews. 200.11 Section 200.11 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE...

  1. 23 CFR 200.11 - Procedures for processing Title VI reviews.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... appropriate action in accordance with 49 CFR. ... 23 Highways 1 2013-04-01 2013-04-01 false Procedures for processing Title VI reviews. 200.11 Section 200.11 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE...

  2. 23 CFR 200.11 - Procedures for processing Title VI reviews.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... appropriate action in accordance with 49 CFR. ... 23 Highways 1 2010-04-01 2010-04-01 false Procedures for processing Title VI reviews. 200.11 Section 200.11 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE...

  3. 23 CFR 200.11 - Procedures for processing Title VI reviews.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... appropriate action in accordance with 49 CFR. ... 23 Highways 1 2014-04-01 2014-04-01 false Procedures for processing Title VI reviews. 200.11 Section 200.11 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS TITLE...

  4. 15 CFR 400.32 - Procedures for docketing applications and commencement of case review.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 2 2013-01-01 2013-01-01 false Procedures for docketing applications and commencement of case review. 400.32 Section 400.32 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) FOREIGN-TRADE ZONES BOARD, DEPARTMENT OF...

  5. 15 CFR 400.32 - Procedure for review of request for approval of manufacturing or processing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... sought do not involve the election of non-privileged foreign status (19 CFR 146.42) on items involving... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Procedure for review of request for approval of manufacturing or processing. 400.32 Section 400.32 Commerce and Foreign Trade...

  6. 15 CFR 400.32 - Procedure for review of request for approval of manufacturing or processing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... sought do not involve the election of non-privileged foreign status (19 CFR 146.42) on items involving... 15 Commerce and Foreign Trade 2 2011-01-01 2011-01-01 false Procedure for review of request for approval of manufacturing or processing. 400.32 Section 400.32 Commerce and Foreign Trade...

  7. 15 CFR 400.32 - Procedure for review of request for approval of manufacturing or processing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... sought do not involve the election of non-privileged foreign status (19 CFR 146.42) on items involving... 15 Commerce and Foreign Trade 2 2012-01-01 2012-01-01 false Procedure for review of request for approval of manufacturing or processing. 400.32 Section 400.32 Commerce and Foreign Trade...

  8. 15 CFR 400.32 - Procedures for docketing applications and commencement of case review.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 2 2014-01-01 2014-01-01 false Procedures for docketing applications and commencement of case review. 400.32 Section 400.32 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) FOREIGN-TRADE ZONES BOARD, DEPARTMENT OF...

  9. 78 FR 30733 - Modernizing Federal Infrastructure Review and Permitting Regulations, Policies, and Procedures

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-22

    ... From the Federal Register Online via the Government Publishing Office #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 78, No. 99 / Wednesday, May 22, 2013 / Presidential Documents#0;#0; ] Memorandum of May 17, 2013 Modernizing Federal Infrastructure Review and Permitting Regulations, Policies, and Procedures Memorandum for the Heads...

  10. A Qualitative Analysis of the Determinants in the Choice of a French Journal Reviewing Procedures

    ERIC Educational Resources Information Center

    Morge, Ludovic

    2015-01-01

    Between 1993 and 2010, two French journals (Aster and Didaskalia) coming from different backgrounds but belonging to the same institution used to publish papers on research in science and technology education. The merging of these journals made it necessary for them to compare the different reviewing procedures used by each. This merging occurred…

  11. 34 CFR 366.38 - What are the procedures for review of centers?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION CENTERS FOR INDEPENDENT LIVING... § 366.38 What are the procedures for review of centers? (a) The Director shall, in accordance with... selected by the Director and the chairperson of the SILC, or other individual designated by the SILC to...

  12. The Generalization of Behavior Modification Procedures: A Review--with Special Emphasis on Classroom Applications

    ERIC Educational Resources Information Center

    Wildman, Robert W., II; Wildman, Robert W.

    1975-01-01

    Reports of the use of behavior modification in the classroom are reviewed, with special attention given to whether or not generalization of the effects of the behavior modification programs was obtained. The authors develop a set of 15 proposed "rules" for obtaining generalization of the effects of behavior modification procedures. (Author)

  13. A qualitative analysis of the determinants in the choice of a French journal reviewing procedures

    NASA Astrophysics Data System (ADS)

    Morge, Ludovic

    2015-12-01

    Between 1993 and 2010, two French journals (Aster and Didaskalia) coming from different backgrounds but belonging to the same institution used to publish papers on research in science and technology education. The merging of these journals made it necessary for them to compare the different reviewing procedures used by each. This merging occurred at a time when research is becoming increasingly international which partly determines some of the reviewing procedure choices. In order for a francophone international journal to survive, it needs to take this internationalization into account in a reasoned manner. The author of this article, as a chief editor of RDST (Recherches en Didactique des Sciences et des Technologies)—the journal resulting from the merging- taking part in this merger, analyses the social, cultural and pragmatic determinants which impacted the choices made in reviewing procedures. This paper describes how these diversity of factors leads us to drop the idea of a standard reviewing procedure which would be valid for all journals.

  14. 32 CFR 861.5 - DOD Commercial Airlift Review Board procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false DOD Commercial Airlift Review Board procedures. 861.5 Section 861.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE... consider reinstating a suspended carrier on either CARB motion or carrier motion, unless such carrier...

  15. 32 CFR 861.5 - DOD Commercial Airlift Review Board procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false DOD Commercial Airlift Review Board procedures. 861.5 Section 861.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE... consider reinstating a suspended carrier on either CARB motion or carrier motion, unless such carrier...

  16. 32 CFR 861.5 - DOD Commercial Airlift Review Board procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false DOD Commercial Airlift Review Board procedures. 861.5 Section 861.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE... consider reinstating a suspended carrier on either CARB motion or carrier motion, unless such carrier...

  17. 14 CFR 435.43 - Payload reentry review requirements and procedures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Payload reentry review requirements and procedures. 435.43 Section 435.43 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING REENTRY OF A REENTRY VEHICLE OTHER THAN A REUSABLE LAUNCH VEHICLE (RLV) Payload...

  18. 40 CFR 63.54 - Preconstruction review procedures for new affected sources.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES Requirements for Control Technology Determinations for Major Sources in Accordance With Clean Air Act Sections, Sections 112(g) and 112(j) § 63.54 Preconstruction review procedures for new...

  19. 40 CFR 63.54 - Preconstruction review procedures for new affected sources.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES Requirements for Control Technology Determinations for Major Sources in Accordance With Clean Air Act Sections, Sections 112(g) and 112(j) § 63.54 Preconstruction review procedures for new...

  20. 40 CFR 63.54 - Preconstruction review procedures for new affected sources.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES Requirements for Control Technology Determinations for Major Sources in Accordance With Clean Air Act Sections, Sections 112(g) and 112(j) § 63.54 Preconstruction review procedures for new...

  1. 32 CFR 766.8 - Procedure for review, approval, execution and distribution of aviation facility licenses.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... CIVIL AIRCRAFT § 766.8 Procedure for review, approval, execution and distribution of aviation facility... license and Certificate of Insurance to the Commander, Naval Facilities Engineering Command or his... Facilities Engineering Command or his designated representative. (1) Upon receipt, the Commander,...

  2. 32 CFR 766.8 - Procedure for review, approval, execution and distribution of aviation facility licenses.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CIVIL AIRCRAFT § 766.8 Procedure for review, approval, execution and distribution of aviation facility... license and Certificate of Insurance to the Commander, Naval Facilities Engineering Command or his... Facilities Engineering Command or his designated representative. (1) Upon receipt, the Commander,...

  3. 32 CFR 766.8 - Procedure for review, approval, execution and distribution of aviation facility licenses.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CIVIL AIRCRAFT § 766.8 Procedure for review, approval, execution and distribution of aviation facility... license and Certificate of Insurance to the Commander, Naval Facilities Engineering Command or his... Facilities Engineering Command or his designated representative. (1) Upon receipt, the Commander,...

  4. 32 CFR 766.8 - Procedure for review, approval, execution and distribution of aviation facility licenses.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... CIVIL AIRCRAFT § 766.8 Procedure for review, approval, execution and distribution of aviation facility... license and Certificate of Insurance to the Commander, Naval Facilities Engineering Command or his... Facilities Engineering Command or his designated representative. (1) Upon receipt, the Commander,...

  5. 32 CFR 766.8 - Procedure for review, approval, execution and distribution of aviation facility licenses.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CIVIL AIRCRAFT § 766.8 Procedure for review, approval, execution and distribution of aviation facility... license and Certificate of Insurance to the Commander, Naval Facilities Engineering Command or his... Facilities Engineering Command or his designated representative. (1) Upon receipt, the Commander,...

  6. 21 CFR 814.44 - Procedures for review of a PMA.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) MEDICAL DEVICES PREMARKET APPROVAL OF MEDICAL DEVICES FDA Action on a PMA § 814.44 Procedures for review... effectiveness of the device, which was the basis for the order approving the PMA, including information about any adverse effects of the device on health, is available on the Internet and has been placed...

  7. 21 CFR 814.44 - Procedures for review of a PMA.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) MEDICAL DEVICES PREMARKET APPROVAL OF MEDICAL DEVICES FDA Action on a PMA § 814.44 Procedures for review... effectiveness of the device, which was the basis for the order approving the PMA, including information about any adverse effects of the device on health, is available on the Internet and has been placed...

  8. 21 CFR 814.44 - Procedures for review of a PMA.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) MEDICAL DEVICES PREMARKET APPROVAL OF MEDICAL DEVICES FDA Action on a PMA § 814.44 Procedures for review... detailed summary of information respecting the safety and effectiveness of the device, which was the basis for the order approving the PMA, including information about any adverse effects of the device...

  9. 47 CFR 76.945 - Procedures for Commission review of basic service rates.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... service rates. 76.945 Section 76.945 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Cable Rate Regulation § 76.945 Procedures for Commission review of basic service rates. (a) Upon assumption of rate regulation...

  10. 47 CFR 76.945 - Procedures for Commission review of basic service rates.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... service rates. 76.945 Section 76.945 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Cable Rate Regulation § 76.945 Procedures for Commission review of basic service rates. (a) Upon assumption of rate regulation...

  11. 47 CFR 76.945 - Procedures for Commission review of basic service rates.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... service rates. 76.945 Section 76.945 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Cable Rate Regulation § 76.945 Procedures for Commission review of basic service rates. (a) Upon assumption of rate regulation...

  12. 47 CFR 76.945 - Procedures for Commission review of basic service rates.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... service rates. 76.945 Section 76.945 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Cable Rate Regulation § 76.945 Procedures for Commission review of basic service rates. (a) Upon assumption of rate regulation...

  13. 47 CFR 76.945 - Procedures for Commission review of basic service rates.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... service rates. 76.945 Section 76.945 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Cable Rate Regulation § 76.945 Procedures for Commission review of basic service rates. (a) Upon assumption of rate regulation...

  14. 77 FR 36532 - Review of Small Generator Interconnection Agreements and Procedures; Solar Energy Industries...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-19

    ...-001; ER12-1855-000] Review of Small Generator Interconnection Agreements and Procedures; Solar Energy....gov/whats-new/registration/small-generator-7-17-12-form.asp . The purpose of this conference is to...: https://www.ferc.gov/whats-new/registration/small-generator-7-17-12-speaker-form.asp . Due to...

  15. Procedural sedation: A review of sedative agents, monitoring, and management of complications

    PubMed Central

    Tobias, Joseph D.; Leder, Marc

    2011-01-01

    Given the continued increase in the complexity of invasive and noninvasive procedures, healthcare practitioners are faced with a larger number of patients requiring procedural sedation. Effective sedation and analgesia during procedures not only provides relief of suffering, but also frequently facilitates the successful and timely completion of the procedure. However, any of the agents used for sedation and/or analgesia may result in adverse effects. These adverse effects most often affect upper airway patency, ventilatory function or the cardiovascular system. This manuscript reviews the pharmacology of the most commonly used agents for sedation and outlines their primary effects on respiratory and cardiovascular function. Suggested guidelines for the avoidance of adverse effects through appropriate pre-sedation evaluation, early identification of changes in respiratory and cardiovascular function, and their treatment are outlined. PMID:22144928

  16. Non-Parenteral Medications for Procedural Sedation in Children- A Narrative: Review Article.

    PubMed

    Fallah, Razieh; Ferdosian, Farzad; Shajari, Ahmad

    2015-01-01

    Procedural sedation may be needed in many diagnostic and therapeutic procedures in children. To make pediatric procedural sedation as safe as possible, protocols should be developed by institutions. Response to sedation in children is highly variable, while some become deeply sedated after minimal doses, others may need much higher doses. Child developmental status, clinical circumstances and condition of patient should be considered and then pharmacologic and non-pharmacologic interventions for sedation be selected. Drug of choice and administration route depend on the condition of the child, type of procedure, and predicted pain degree. The drugs might be administered parenteral (intravenous or intramuscular) or non parenteral including oral, rectal, sublingual, aerosolized buccal and intranasal. The use of intravenous medication such propofol, ketamine, dexmedetomidine, or etomidate may be restricted in use by pediatric anesthesiologist or pediatric critical care specialists or pediatric emergency medicine specialists. In this review article we discuss on non-parenteral medications that can be used by non- anesthesiologist. PMID:26401146

  17. Non-Parenteral Medications for Procedural Sedation in Children- A Narrative: Review Article

    PubMed Central

    FALLAH, Razieh; FERDOSIAN, Farzad; SHAJARI, Ahmad

    2015-01-01

    Procedural sedation may be needed in many diagnostic and therapeutic procedures in children. To make pediatric procedural sedation as safe as possible, protocols should be developed by institutions. Response to sedation in children is highly variable, while some become deeply sedated after minimal doses, others may need much higher doses. Child developmental status, clinical circumstances and condition of patient should be considered and then pharmacologic and non-pharmacologic interventions for sedation be selected. Drug of choice and administration route depend on the condition of the child, type of procedure, and predicted pain degree. The drugs might be administered parenteral (intravenous or intramuscular) or non parenteral including oral, rectal, sublingual, aerosolized buccal and intranasal. The use of intravenous medication such propofol, ketamine, dexmedetomidine, or etomidate may be restricted in use by pediatric anesthesiologist or pediatric critical care specialists or pediatric emergency medicine specialists. In this review article we discuss on non-parenteral medications that can be used by non- anesthesiologist. PMID:26401146

  18. Welfare implications of invasive piglet husbandry procedures, methods of alleviation and alternatives: a review.

    PubMed

    Sutherland, M A

    2015-01-01

    Iron administration, teeth clipping, tail docking and castration are common invasive husbandry procedures performed on piglets on commercial farms, generally within the first week of life. These procedures are performed to prevent potential health and welfare problems of piglets and/or the sow, or, with respect to castration, to enhance meat quality. The objectives of this review were firstly, to provide the rationale and scientific evidence for performing these procedures, secondly, to describe the welfare implications of these procedures, and lastly, to describe mitigation strategies or alternatives that can be used to eliminate or reduce the pain caused by these procedures. Administering supplementary iron is necessary to prevent anaemia in piglets and the procedure has a low welfare impact. The stated benefits of teeth clipping to prevent udder lesions do not appear to outweigh the risk from injury and infection in piglets following the procedure. Tail docking reduces the prevalence of tail biting, but does not eliminate this behaviour and the practice of tail docking can cause acute pain. Castration is primarily performed to reduce the occurrence of boar taint, but alternatives are now available that negate the need to perform this procedure. Teeth clipping, tail docking and castration all cause behavioural and physiological changes indicative of acute pain and can have potentially long-term negative consequences such as causing abscesses, lesions and the formation of neuromas. Therefore effective pain mitigation strategies (e.g. analgesia, local or general anaesthesia) that markedly alleviate the pain caused by these procedures are necessary to improve the welfare of piglets. Alternatively, if management practices are available that eliminate the need for performing these procedures altogether, then they should be adopted. PMID:25204203

  19. 36 CFR 1260.42 - What are the procedures for agency personnel to review records at a NARA facility?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... SECURITY INFORMATION Systematic Review § 1260.42 What are the procedures for agency personnel to review... damage to archival materials. See 36 CFR part 1254 for more information on acceptable equipment....

  20. Dissemination of Periodontal Pathogens in the Bloodstream after Periodontal Procedures: A Systematic Review

    PubMed Central

    Horliana, Anna Carolina Ratto Tempestini; Chambrone, Leandro; Foz, Adriana Moura; Artese, Hilana Paula Carillo; Rabelo, Mariana de Sousa; Pannuti, Cláudio Mendes; Romito, Giuseppe Alexandre

    2014-01-01

    Background To date, there is no compilation of evidence-based information associating bacteremia and periodontal procedures. This systematic review aims to assess magnitude, duration, prevalence and nature of bacteremia caused by periodontal procedures. Study Design Systematic Review Types of Studies Reviewed MEDLINE, EMBASE and LILACS databases were searched in duplicate through August, 2013 without language restriction. Observational studies were included if blood samples were collected before, during or after periodontal procedures of patients with periodontitis. The methodological quality was assessed in duplicate using the modified Newcastle-Ottawa scale (NOS). Results Search strategy identified 509 potentially eligible articles and nine were included. Only four studies demonstrated high methodological quality, whereas five were of medium or low methodological quality. The study characteristics were considered too heterogeneous to conduct a meta-analysis. Among 219 analyzed patients, 106 (49.4%) had positive bacteremia. More frequent bacteria were S. viridans, A. actinomycetemcomitans P. gingivalis, M. micros and species Streptococcus and Actinomyces, although identification methods of microbiologic assays were different among studies. Clinical Implications Although half of the patients presented positive bacteremia after periodontal procedures, accurate results regarding the magnitude, duration and nature of bacteremia could not be confidentially assessed. PMID:24870125

  1. Risk of bleeding associated with interventional musculoskeletal radiology procedures. A comprehensive review of the literature.

    PubMed

    Foremny, Gregory B; Pretell-Mazzini, Juan; Jose, Jean; Subhawong, Ty K

    2015-05-01

    This review compiles the current literature on the bleeding risks in common musculoskeletal interventional procedures and attempts to provide guidance for practicing radiologists in making decisions regarding the periprocedural management of patients on antithrombotic therapy. The practitioner must weigh the risk of bleeding if therapy is continued against the possibility a thromboembolic occurring if anticoagulation therapy is withheld or reversed. Unfortunately, there is little empirical data to guide evidence-based decisions for many musculoskeletal interventions. However, a review of the literature shows that for low-risk procedures, such as arthrograms/arthrocenteses or muscle/tendon sheath injections, bleeding risks are sufficiently small that anticoagulants and antiplatelet therapies need not be withheld. Additionally, relatively higher-risk procedures, such as needle biopsies of bone and soft tissue, may be safely performed without holding antithrombotic therapy, provided pre-procedural INR is within therapeutic range. Thus, while a patient's particular clinical circumstances should dictate optimal individualized management, anticoagulation alone is not a general contraindication to most interventional musculoskeletal radiology procedures. PMID:25433718

  2. Canopy Level Chlorophyll Fluorescence and the PRI in a Cornfield

    NASA Technical Reports Server (NTRS)

    Middleton, Elizabeth M.; Cheng, Yen-Ben; Corp, Lawrence A.; Campbell, Petya K. E.; Huemmrich, K. Fred; Zhang, Qingyuan; Kustas, William P.

    2012-01-01

    Two bio-indicators, the Photochemical Reflectance Index (PRI) and solar-induced red and far-red Chlorophyll Fluorescence (SIF), were derived from directional hyperspectral observations and studied in a cornfield on two contrasting days in the growing season. Both red and far-red SIF exhibited higher values on the day when the canopy in the early senescent stage, but only the far-red SIF showed sensitivity to viewing geometry. Consequently, the red/far-red SIF ratio varied greatly among azimuth positions while the largest values were obtained for the "hotspot" at both growth stages. This ratio was lower (approx.0.88 +/- 0.4) in early July than in August when the ratio approached equivalence (near approx.1). In concert, the PRI exhibited stronger responses to both zenith and azimuth angles and different values on the two growth stages. The potential of using these indices to monitor photosynthetic activities needs further investigation

  3. 7 CFR 1c.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 1c.110 Section 1c.110 Agriculture Office of the Secretary of Agriculture PROTECTION OF HUMAN SUBJECTS § 1c.110 Expedited review procedures for certain kinds...

  4. 22 CFR 225.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 225.110 Section 225.110 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT PROTECTION OF HUMAN SUBJECTS § 225.110 Expedited review procedures for...

  5. 28 CFR 46.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 46.110 Section 46.110 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PROTECTION OF HUMAN SUBJECTS § 46.110 Expedited review procedures...

  6. 10 CFR 745.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 745.110 Section 745.110 Energy DEPARTMENT OF ENERGY PROTECTION OF HUMAN SUBJECTS § 745.110 Expedited review procedures for certain kinds of research involving no...

  7. 49 CFR 11.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 11.110 Section 11.110 Transportation Office of the Secretary of Transportation PROTECTION OF HUMAN SUBJECTS § 11.110 Expedited review procedures for...

  8. 10 CFR 745.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 745.110 Section 745.110 Energy DEPARTMENT OF ENERGY PROTECTION OF HUMAN SUBJECTS § 745.110 Expedited review procedures for certain kinds of research involving no...

  9. 22 CFR 225.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 225.110 Section 225.110 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT PROTECTION OF HUMAN SUBJECTS § 225.110 Expedited review procedures for...

  10. 10 CFR 745.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 745.110 Section 745.110 Energy DEPARTMENT OF ENERGY PROTECTION OF HUMAN SUBJECTS § 745.110 Expedited review procedures for certain kinds of research involving no...

  11. 10 CFR 745.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 745.110 Section 745.110 Energy DEPARTMENT OF ENERGY PROTECTION OF HUMAN SUBJECTS § 745.110 Expedited review procedures for certain kinds of research involving no...

  12. Prodifferentiation Activity of Novel Vitamin D₂ Analogs PRI-1916 and PRI-1917 and Their Combinations with a Plant Polyphenol in Acute Myeloid Leukemia Cells.

    PubMed

    Nachliely, Matan; Sharony, Ehud; Bolla, Narasimha Rao; Kutner, Andrzej; Danilenko, Michael

    2016-01-01

    1α,25-dihydroxyvitamin D₃ (1,25D3) is a powerful differentiation inducer for acute myeloid leukemia (AML) cells. However, 1,25D3 doses required for differentiation of AML cells may cause lethal hypercalcemia in vivo. There is evidence that vitamin D₂ is less toxic than vitamin D₃ in animals. Here, we determined the differentiation effects of novel analogs of 1α,25-dihydroxyvitamin D₂ (1,25D2), PRI-1916 and PRI-1917, in which the extended side chains of their previously reported precursors (PRI-1906 and PRI-1907, respectively) underwent further 24Z (24-cis) modification. Using four human AML cell lines representing different stages of myeloid maturation (KG-1a, HL60, U937, and MOLM-13), we found that the potency of PRI-1916 was slightly higher or equal to that of PRI-1906 while PRI-1917 was significantly less potent than PRI-1907. We also demonstrated that 1,25D2 was a less effective differentiation agent than 1,25D3 in these cell lines. Irrespective of their differentiation potency, all the vitamin D₂ derivatives tested were less potent than 1,25D3 in transactivating the DR3-type vitamin D response elements. However, similar to 1,25D3, both 1,25D2 and its analogs could strongly cooperate with the plant polyphenol carnosic acid in inducing cell differentiation and inhibition of G1-S cell cycle transition. These results indicate that the 24Z modification has contrasting effects on the differentiation ability of PRI-1906 and PRI-1907 and that the addition of a plant polyphenol could result in a similar extent of cell differentiation induced by different vitamin D compounds. The enhanced antileukemic effects of the tested combinations may constitute the basis for the development of novel approaches for differentiation therapy of AML. PMID:27399677

  13. Prodifferentiation Activity of Novel Vitamin D2 Analogs PRI-1916 and PRI-1917 and Their Combinations with a Plant Polyphenol in Acute Myeloid Leukemia Cells

    PubMed Central

    Nachliely, Matan; Sharony, Ehud; Bolla, Narasimha Rao; Kutner, Andrzej; Danilenko, Michael

    2016-01-01

    1α,25-dihydroxyvitamin D3 (1,25D3) is a powerful differentiation inducer for acute myeloid leukemia (AML) cells. However, 1,25D3 doses required for differentiation of AML cells may cause lethal hypercalcemia in vivo. There is evidence that vitamin D2 is less toxic than vitamin D3 in animals. Here, we determined the differentiation effects of novel analogs of 1α,25-dihydroxyvitamin D2 (1,25D2), PRI-1916 and PRI-1917, in which the extended side chains of their previously reported precursors (PRI-1906 and PRI-1907, respectively) underwent further 24Z (24-cis) modification. Using four human AML cell lines representing different stages of myeloid maturation (KG-1a, HL60, U937, and MOLM-13), we found that the potency of PRI-1916 was slightly higher or equal to that of PRI-1906 while PRI-1917 was significantly less potent than PRI-1907. We also demonstrated that 1,25D2 was a less effective differentiation agent than 1,25D3 in these cell lines. Irrespective of their differentiation potency, all the vitamin D2 derivatives tested were less potent than 1,25D3 in transactivating the DR3-type vitamin D response elements. However, similar to 1,25D3, both 1,25D2 and its analogs could strongly cooperate with the plant polyphenol carnosic acid in inducing cell differentiation and inhibition of G1–S cell cycle transition. These results indicate that the 24Z modification has contrasting effects on the differentiation ability of PRI-1906 and PRI-1907 and that the addition of a plant polyphenol could result in a similar extent of cell differentiation induced by different vitamin D compounds. The enhanced antileukemic effects of the tested combinations may constitute the basis for the development of novel approaches for differentiation therapy of AML. PMID:27399677

  14. Implicit Memory in Korsakoff’s Syndrome: A Review of Procedural Learning and Priming Studies

    PubMed Central

    Hayes, Scott M.; Fortier, Catherine B.; Levine, Andrea; Milberg, William P.; McGlinchey, Regina

    2013-01-01

    Korsakoff’s syndrome (KS) is characterized by dense anterograde amnesia resulting from damage to the diencephalon region, typically resulting from chronic alcohol abuse and thiamine deficiency. This review assesses the integrity of the implicit memory system in KS, focusing on studies of procedural learning and priming. KS patients are impaired on several measures of procedural memory, most likely due to impairment in cognitive functions associated with alcohol-related neural damage outside of the diencephalon. The pattern of performance on tasks of implicit priming suggests reliance on a residual, non-flexible memory operating more or less in an automatic fashion. Our review concludes that whether measures of implicit memory reveal intact or impaired performance in individuals with KS depends heavily on specific task parameters and demands, including timing between stimuli, the specific nature of the stimuli used in a task, and the integrity of supportive cognitive functions necessary for performance. PMID:22592661

  15. Anesthesia for Advanced Bronchoscopic Procedures: State-of-the-Art Review.

    PubMed

    Goudra, Basavana G; Singh, Preet Mohinder; Borle, Anuradha; Farid, Nahla; Harris, Kassem

    2015-08-01

    The bronchoscopic procedures have seen a remarkable increase in both numbers and complexity. Although many anesthesia providers have kept pace with the challenge, the practice is varied and frequently suboptimal. Shared airway during bronchoscopy poses unique challenges. The available reviews have tried to address this lacuna; however, these have frequently dealt with the technical aspects of bronchoscopy than anesthetic challenges. The present review provides evidence-based management insights into anesthesia for bronchoscopy-both flexible and rigid. A systematic approach toward pre-procedural evaluation and risk stratification is presented. The possible anatomical and physiological factors that can influence the outcomes are discussed. Pharmacological principles guiding sedation levels and appropriate selection of sedatives form the crux of safe anesthetic management. The newer and safer drugs that can have potential role in anesthesia for bronchoscopy in the near future are discussed. Ventilatory strategies during bronchoscopy for prevention of hypoxia and hypercarbia are emphasized. PMID:25921014

  16. Comparison of the predictive validity and consistency among preference assessment procedures: a review of the literature.

    PubMed

    Kang, Soyeon; O'Reilly, Mark; Lancioni, Giulio; Falcomata, Terry S; Sigafoos, Jeff; Xu, Ziwei

    2013-04-01

    We reviewed 14 experimental studies comparing different preference assessments for individuals with developmental disabilities that were published in peer-reviewed journals between 1985 and 2012. Studies were summarized based on the following six variables: (a) the number of participants, (b) the type of disability, (c) the number and type of stimuli, (d) the average duration of administration, (e) compared procedures, and (f) results. Studies were also classified in terms of the predictive validity and consistency of the preference assessment results. The results suggest the preference assessment procedures that may produce more accurate predictions for the reinforcing effects of identified stimuli and consistent preference results. The findings are discussed in relation to the previous literature. Evidence based modifications of the most efficient preference assessment are also discussed. PMID:23357675

  17. Implicit memory in Korsakoff's syndrome: a review of procedural learning and priming studies.

    PubMed

    Hayes, Scott M; Fortier, Catherine B; Levine, Andrea; Milberg, William P; McGlinchey, Regina

    2012-06-01

    Korsakoff's syndrome (KS) is characterized by dense anterograde amnesia resulting from damage to the diencephalon region, typically resulting from chronic alcohol abuse and thiamine deficiency. This review assesses the integrity of the implicit memory system in KS, focusing on studies of procedural learning and priming. KS patients are impaired on several measures of procedural memory, most likely due to impairment in cognitive functions associated with alcohol-related neural damage outside of the diencephalon. The pattern of performance on tasks of implicit priming suggests reliance on a residual, non-flexible memory operating more or less in an automatic fashion. Our review concludes that whether measures of implicit memory reveal intact or impaired performance in individuals with KS depends heavily on specific task parameters and demands, including timing between stimuli, the specific nature of the stimuli used in a task, and the integrity of supportive cognitive functions necessary for performance. PMID:22592661

  18. Is acupuncturing effective in controlling the gag reflex during dental procedures? A review of literature

    PubMed Central

    Daneshkazemi, Alireza; Daneshkazemi, Pedram; Davoudi, Amin; Badrian, Hamid; Firouzabadi, Vahid Pourtalebi

    2016-01-01

    Traditional acupuncture has been introduced more than 2500 years ago which provides an alternative and complementary option during clinical practices. Its main mechanism is based on stimulating the nerves by altering the processes and perception of pain transmitters. It facilitates releasing natural pain relievers such as endorphins and serotonin. Its success for various dental procedures has been proved earlier. However, its effects on controlling the gag reflex seem to be overlooked. The gag reflex is recognized as a protective reaction for stopping the entrance of any foreign bodies into the oropharynx. Pronounced gag reflexes can have negative impacts on the quality of dental procedures. Many techniques have been suggested for managing this reflex and acupuncturing is one of those which seems to be overlooked recently. The aim of this paper is reviewing the published high-quality researches about the efficacy of this technique for eliminating the gag reflex during dental procedures. PMID:27212742

  19. Endoscopic procedures of the upper-thoracic sympathetic chain. A review.

    PubMed

    Drott, C; Göthberg, G; Claes, G

    1993-02-01

    The upsurge of endoscopic surgical procedures now includes procedures of the thoracic sympathetic chain. The number of articles on this issue is rapidly increasing. This article reviews the indications for as well as the technique, complications, side effects, and results of endoscopic upper-thoracic sympathetic ablation. Since 1977, nearly 900 cases have been described in the literature. The main indication is usually hyperhidrosis. The described techniques vary in detail, but the common denominators are simplicity, expedience, minimal surgical trauma, few complications, and low cost compared with standard methods of open surgery. The results are excellent, durable, and stand well compared with results of previous open techniques. Due to the overwhelming advantages of endoscopic methods, we can foresee an increasing adoption of these techniques and a subsequent relegation of the various open surgical procedures of the upper-thoracic sympathetic chain. PMID:8431126

  20. MS Peterson eats while reviewing procedures with Commander Weitz on middeck

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Mission Specialist (MS) Peterson, holding food container, eats while reviewing procedures with Commander Weitz (wearing bifocals) on middeck in front of starboard wall. Weitz points out an item in the frew activity plan (CAP) to Peterson as the mission specialist uses a spoon to eat a meal aboard the Earth-orbiting Challenger, Orbiter Vehicle (OV) 099. Weitz and Peterson are wearing the shirt and trouser portions of the light blue cotton multi-piece constant wear garments.

  1. Efficacy of the enamel matrix derivative in direct pulp capping procedures: a systematic review.

    PubMed

    Al-Hezaimi, Khalid; Javed, Fawad; Al-Fouzan, Khalid; Tay, Franklin

    2013-12-01

    The aim was to review the efficacy of the enamel matrix derivative (EMD) in direct pulp capping (DPC) procedures. Databases were explored using the following keywords: 'dental', 'dentine', 'enamel matrix derivative', 'pulp capping' and 'treatment'. The inclusion criteria were: (i) original studies; (ii) human and animal studies; (iii) reference list of potentially relevant original and review articles; (iv) intervention: effect of EMD on pulp-capping procedures; and (v) articles published only in English. Eight studies (four human and four animal) were included. Among the human studies, two studies reported that EMD is a more efficient DPC procedure compared with calcium hydroxide (Ca(OH)2 ). One study reported Ca(OH)2 to be more efficient for DPC than EMD. One study reported no difference in the efficacies between EMD and Ca(OH)2 for DPC. All animal studies reported EMD to be more effective in reparative dentine formation in comparison with Ca(OH)2 . EMD can provide favourable results in DPC procedures. PMID:24279667

  2. Considerations for the direct pulp capping procedure in primary teeth: a review of the literature.

    PubMed

    Kopel, H M

    1992-01-01

    In reviewing the various studies concerning the direct pulp capping procedure in primary teeth, using rigid criteria for case selection and procedure appears to insure a significant amount of success. It is acknowledged that vital primary pulp tissue is capable of healing without resorting to complete pulpectomy, although statistically direct pulp capping has been found to be less successful in primary teeth than indirect pulp therapy or coronal amputation (pulpotomy). To achieve success for direct pulp capping in primary teeth, the considerations involve: selecting teeth with minimal or no clinical signs of pulpal inflammation; or pretreating the carious tooth with a sedative restoration before excavating the caries; disinfecting the cavity floor; enlarging the actual exposure, and flushing out dentinal debris with mild solutions; controlling bleeding by not allowing a clot to form; placing a hard-set, CaOH material over the exposure, followed by a fast-setting, zinc oxide-eugenol cement to achieve a hermetic seal; and lastly, placing a stainless steel crown to minimize microleakage and prevent a fractured or defective restoration. These procedural steps can hardly ensure complete success in direct pulp capping of a primary tooth; but, based on the many cited investigations in this review, a significant amount of success can be expected without resorting more frequently to invasive techniques. Surely the evidence presented leading to the feasibility of direct pulp capping in primary teeth merits further investigations, before dogmatically rejecting this procedure of pulp therapy. PMID:1583199

  3. A Review of CAM for Procedural Pain in Infancy: Part II. Other Interventions.

    PubMed

    Tsao, Jennie C I; Evans, Subhadra; Meldrum, Marcia; Altman, Tamara; Zeltzer, Lonnie K

    2008-12-01

    This article is the second in a two-part series reviewing the empirical evidence for complementary and alternative medicine (CAM) approaches for the management of pain related to medical procedures in infants up to 6 weeks of age. Part I of this series investigated the effects of sucrose with or without non-nutritive sucking (NNS). The present article examines other CAM interventions for procedural pain including music-based interventions, olfactory stimulation, kangaroo care and swaddling. Computerized databases were searched for relevant studies including prior reviews and primary trials. Preliminary support was revealed for the analgesic effects of the CAM modalities reviewed. However, the overall quality of the evidence for these approaches remains relatively weak. Additional well-designed trials incorporating rigorous methodology are required. Such investigations will assist in the development of evidence-based guidelines on the use of CAM interventions either alone or in concert with conventional approaches to provide safe, reliable analgesia for infant procedural pain. PMID:18955254

  4. REVIEW Of COMPUTERIZED PROCEDURE GUIDELINES FOR NUCLEAR POWER PLANT CONTROL ROOMS

    SciTech Connect

    David I Gertman; Katya Le Blanc; Ronald L Boring

    2011-09-01

    Computerized procedures (CPs) are recognized as an emerging alternative to paper-based procedures for supporting control room operators in nuclear power plants undergoing life extension and in the concept of operations for advanced reactor designs. CPs potentially reduce operator workload, yield increases in efficiency, and provide for greater resilience. Yet, CPs may also adversely impact human and plant performance if not designed and implemented properly. Therefore, it is important to ensure that existing guidance is sufficient to provide for proper implementation and monitoring of CPs. In this paper, human performance issues were identified based on a review of the behavioral science literature, research on computerized procedures in nuclear and other industries, and a review of industry experience with CPs. The review of human performance issues led to the identification of a number of technical gaps in available guidance sources. To address some of the gaps, we developed 13 supplemental guidelines to support design and safety. This paper presents these guidelines and the case for further research.

  5. Continuous neuropathic pain secondary to endoscopic procedures: report of two cases and review of the literature.

    PubMed

    Kalladka, Mythili; Nasri-Heir, Cibele; Eliav, Eli; Ananthan, Sowmya; Viswanath, Archana; Heir, Gary

    2016-08-01

    Neuropathic pain encompasses a spectrum of conditions that can arise from a lesion or dysfunction of the central or the peripheral nervous system, and it may develop at variable intervals after nerve injury or inflammation. Nerve injuries arising from surgical procedures commonly occur secondary to the surgical trauma, and in rare instances they are a complication of intubation during general anesthesia or endoscopic procedures. A series of 2 cases of bilateral glossopharyngeal neuropathic pain subsequent to endoscopic procedures is presented with a review of the literature concerning the mechanisms of development of neuropathic pain after these procedures. The purpose of these case reports is to make dentists aware of the occurrence, the mechanisms of nerve injuries, and the treatment of neuropathic pain after endoscopic procedures. In the first case, the patient had relief of pain with a combination therapy of clonazepam 1.0 mg in divided doses twice daily and gabapentin 300 mg in divided doses 3 times daily. In the second case, the patient had significant relief of pain with a monotherapy of gabapentin 1200 mg in divided doses 3 times daily. PMID:27422430

  6. Review of Test Procedure for Determining HSPFs of Residential Variable-Speed Heat Pumps

    SciTech Connect

    Rice, C. Keith; Munk, Jeffrey D.; Shrestha, Som S.

    2015-08-01

    This report reviews the suitability of the existing Heating Seasonal Performance Factor (HSPF) ratings and testing requirements for the current generation of variable-speed (VS) air-source heat pumps. Recent field test results indicate larger discrepancies between rated HSPF and field-observed HSPF for VS models than for single-speed models in the same houses. These findings suggest that the heating season test and ratings procedure should be revisited for VS heat pumps. The ratings and testing procedures are described in ANSI/AHRI 210/240 (2008) for single-speed, two-capacity, and variable-speed units. Analysis of manufacturer and independent test performance data on VS units reveals why the current VS testing/ratings procedure results in overly optimistic HSPF ratings for some VS units relative to other types of heat pumps. This is due to a combination of extrapolation of low speed test data beyond the originally anticipated ambient temperature operating range and the constraints of unit controls, which prevent low speed operation over the range of ambient temperatures assumed in the procedure for low speed. As a result, the HSPFs of such units are being overpredicted relative to those for single- and two-capacity designs. This overprediction has been found to be significantly reduced by use in the HSPF ratings procedure of an alternative higher-load heating load line, described in a companion report (Rice et al., 2015).

  7. Advanced human-system interface design review guideline. Evaluation procedures and guidelines for human factors engineering reviews

    SciTech Connect

    O`Hara, J.M.; Brown, W.S.; Baker, C.C.; Welch, D.L.; Granda, T.M.; Vingelis, P.J.

    1994-07-01

    Advanced control rooms will use advanced human-system interface (HSI) technologies that may have significant implications for plant safety in that they will affect the operator`s overall role in the system, the method of information presentation, and the ways in which operators interact with the system. The U.S. Nuclear Regulatory Commission (NRC) reviews the HSI aspects of control rooms to ensure that they are designed to good human factors engineering principles and that operator performance and reliability are appropriately supported to protect public health and safety. The principal guidance available to the NRC, however, was developed more than ten years ago, well before these technological changes. Accordingly, the human factors guidance needs to be updated to serve as the basis for NRC review of these advanced designs. The purpose of this project was to develop a general approach to advanced HSI review and the human factors guidelines to support. NRC safety reviews of advanced systems. This two-volume report provides the results of the project. Volume I describes the development of the Advanced HSI Design Review Guideline (DRG) including (1) its theoretical and technical foundation, (2) a general model for the review of advanced HSIs, (3) guideline development in both hard-copy and computer-based versions, and (4) the tests and evaluations performed to develop and validate the DRG. Volume I also includes a discussion of the gaps in available guidance and a methodology for addressing them. Volume 2 provides the guidelines to be used for advanced HSI review and the procedures for their use.

  8. Presenilin-1 influences processing of the acetylcholinesterase membrane anchor PRiMA.

    PubMed

    García-Ayllón, María-Salud; Campanari, María-Letizia; Montenegro, María-Fernanda; Cuchillo-Ibáñez, Inmaculada; Belbin, Olivia; Lleó, Alberto; Tsim, Karl; Vidal, Cecilio J; Sáez-Valero, Javier

    2014-07-01

    Presenilin-1 (PS1) is the catalytic component of the γ-secretase complex. In this study, we explore if PS1 participates in the processing of the cholinergic acetylcholinesterase (AChE). The major AChE variant expressed in the brain is a tetramer (G(4)) bound to a proline-rich membrane anchor (PRiMA). Overexpression of the transmembrane PRiMA protein in Chinese hamster ovary cells expressing AChE and treated with the γ-secretase inhibitor N-[N-(3,5-difluorophenacetyl)-l-alanyl]-S-phenylglycine t-butyl ester have enabled us to study whether, through its γ-secretase activity, PS1 participates in the processing of PRiMA-linked AChE. γ-Secretase inhibition led to a notable increase in the level of PRiMA-linked AChE, suggesting that γ-secretase is involved in the cleavage of PRiMA. We demonstrate that cleavage of PRiMA by γ-secretase results in a C-terminal PRiMA fragment. Immunofluorescence labeling allowed us to identify this PRiMA fragment in the nucleus. Moreover, we have determined changes in the proportion of the raft-residing AChE-PRiMA in a PS1 conditional knockout mouse. Our results are of interest as both enzymes have therapeutic relevance for Alzheimer's disease. PMID:24612677

  9. Atrioesophageal fistula following ablation procedures for atrial fibrillation: systematic review of case reports

    PubMed Central

    Chavez, Patricia; Messerli, Franz H; Casso Dominguez, Abel; Aziz, Emad F; Sichrovsky, Tina; Garcia, Daniel; Barrett, Connor D; Danik, Stephan

    2015-01-01

    Background Atrioesophageal fistula (AEF) is a rare but serious adverse event of atrial fibrillation (AF) ablation. Objective To identify the clinical characteristics of AEF following ablation procedures for AF and determine the associated mortality. Methods A systematic review of observational cases of AEF following ablation procedures for AF was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement protocol. Results 53 cases were identified. Mean age was 54±13 years; 73% (39/53) of cases occurred in males. Mean interval between procedure and presentation was 20±12 days, ranging from 2 to 60 days. AEF was observed in 12 patients who underwent surgical radiofrequency ablation (RFA) and in 41 patients with percutaneous RFA. Fever was the most common presenting symptom (n=44) followed by neurological deficits (n=27) and haematemesis (n=19). CT of the chest (n=27) was the preferred diagnostic test. Patients who did not receive a primary esophageal repair were more likely to have a deadly outcome (34% vs 83%; p<0.05). No difference in mortality rate was found between patients who underwent surgical RFA when compared with percutaneous RFA (58% vs 56%; p=0.579). No association was found between onset of symptoms and mortality (19±10 vs 23±14 days; p=0.355). Conclusions AEF following ablation procedures for AF is a serious complication with high mortality rates. Presenting symptoms most often include a triad of fever, neurological deficit and/or haematemesis within 60 days of procedure. The preferred diagnostic test is CT of the chest. The treatments of choice is surgical repair. PMID:26380098

  10. 36 CFR 1260.58 - What are the procedures for requesting a mandatory review of White House originated information?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... more than 25 years old, NARA will review the records using systematic declassification guidance... requesting a mandatory review of White House originated information? 1260.58 Section 1260.58 Parks, Forests... NATIONAL SECURITY INFORMATION Mandatory Review § 1260.58 What are the procedures for requesting a...

  11. Retrospective review of Contura HDR breast cases to improve our standardized procedure

    SciTech Connect

    Iftimia, Ileana; Cirino, Eileen T.; Ladd, Ron; Mower, Herbert W.; McKee, Andrea B.

    2013-07-01

    To retrospectively review our first 20 Contura high dose rate breast cases to improve and refine our standardized procedure and checklists. We prepared in advance checklists for all steps, developed an in-house Excel spreadsheet for second checking the plan, and generated a procedure for efficient contouring and a set of optimization constraints to meet the dose volume histogram criteria. Templates were created in our treatment planning system for structures, isodose levels, optimization constraints, and plan report. This study reviews our first 20 high dose rate Contura breast treatment plans. We followed our standardized procedure for contouring, planning, and second checking. The established dose volume histogram criteria were successfully met for all plans. For the cases studied here, the balloon-skin and balloon-ribs distances ranged between 5 and 43 mm and 1 and 33 mm, respectively; air{sub s}eroma volume/PTV{sub E}val volume≤5.5% (allowed≤10%); asymmetry<1.2 mm (goal≤2 mm); PTV{sub E}val V90%≥97.6%; PTV{sub E}val V95%≥94.9%; skin max dose≤98%Rx; ribs max dose≤137%Rx; V150%≤29.8 cc; V200%≤7.8 cc; the total dwell time range was 225.4 to 401.9 seconds; and the second check agreement was within 3%. Based on this analysis, more appropriate ranges for the total dwell time and balloon diameter tolerance were found. Three major problems were encountered: balloon migration toward the skin for small balloon-to-skin distances, lumen obstruction, and length change for the flexible balloon. Solutions were found for these issues and our standardized procedure and checklists were updated accordingly. Based on our review of these cases, the use of checklists resulted in consistent results, indicating good coverage for the target without sacrificing the critical structures. This review helped us to refine our standardized procedure and update our checklists.

  12. USING VIDEO TECHNOLOGY TO DISSEMINATE BEHAVIORAL PROCEDURES: A REVIEW OF FUNCTIONAL ANALYSIS: A GUIDE FOR UNDERSTANDING CHALLENGING BEHAVIOR (DVD)

    PubMed Central

    Carr, James E; Fox, Eric J

    2009-01-01

    Although applied behavior analysis has generated many highly effective behavior-change procedures, the procedures have not always been effectively disseminated. One solution to this problem is the use of video technology, which has been facilitated by the ready availability of video production equipment and software and multiple distribution methods (e.g., DVD, online streaming). We review a recent DVD that was produced to disseminate the successful experimental functional analysis procedure. The review is followed by general recommendations for disseminating behavior-analytic procedures via video technology. PMID:20514204

  13. Review of procedures used for the extraction of anti-cancer compounds from tropical plants.

    PubMed

    Pandey, Saurabh; Shaw, Paul N; Hewavitharana, Amitha K

    2015-01-01

    Tropical plants are important sources of anti-cancer lead molecules. According to the US National Cancer Institute, out of the 3000 plants identified as active against cancer using in vitro studies, 70% are of tropical origin. The extraction of bioactive compounds from the plant materials is a fundamental step whose efficiency is critical for the success of drug discovery efforts. There has been no review published of the extraction procedures of anti-cancer compounds from tropical plants and hence the following is a critical evaluation of such procedures undertaken prior to the use of these compounds in cancer cell line studies, during the last five years. It presents a comprehensive analysis of all approaches taken to extract anti-cancer compounds from various tropical plants. (Databases searched were PubMed, SciFinder, Web of Knowledge, Scopus, Embase and Google Scholar). PMID:25403166

  14. Pain and anxiety management for pediatric dental procedures using various combinations of sedative drugs: A review.

    PubMed

    Gazal, Giath; Fareed, Wamiq Musheer; Zafar, Muhammad Sohail; Al-Samadani, Khalid H

    2016-07-01

    For fearful and uncooperative children behavioral management techniques are used. In order to control the pain and anxiety in pedodontic patients, pharmacologic sedation, anesthesia and analgesia are commonly used. Midazolam is commonly used as an oral sedation agent in children; it has several features such as safety of use, quick onset and certain degree of amnesia that makes it a desirable sedation agent in children. This review paper discusses various aspects of oral midazolam, ketamine and their combinations in conscious sedation including, advantages of oral route of sedation, pharmacokinetics, range of oral doses, and antagonists for clinical dental treatment procedures. PMID:27330369

  15. Review of data analysis procedures for the ATS-6 millimeter wave experiment

    NASA Technical Reports Server (NTRS)

    Meneghini, R.

    1975-01-01

    Predictions of satellite downlink attenuation through the use of ground based measurements form a substantial part of the ATS-6 millimeter wave experiment (MWE). At the downlink frequencies (20 and 30 GHz), the major causes of attenuation are the density and the size distribution of rain drops along the propagation path. Ground station data, which include radar and rain gauge records, measure quantities related to the meteorological parameters of interest and thereby provide a prediction of downlink attenuation with which the measured attenuation can be compared. The calibration and data analysis procedures used in the MWE are reviewed with the object of improving the accuracy of such ground based predictions.

  16. A Review and Critique of Procedures for Assessing Speaking and Listening Skills among Preschool through Grade Twelve Students.

    ERIC Educational Resources Information Center

    Rubin, Donald L.; And Others

    1982-01-01

    Reviewed 45 assessment instruments with respect to content domains, response and scoring procedures, administrative feasibility, target populations, and potential sources of test bias. Identified priorities for future research and development in communication competence testing. (PD)

  17. Early Citability of Data vs Peer-Review like Data Publishing Procedures

    NASA Astrophysics Data System (ADS)

    Stockhause, Martina; Höck, Heinke; Toussaint, Frank; Lautenschlager, Michael

    2014-05-01

    The World Data Center for Climate (WDCC) hosted at the German Climate Computing Center (DKRZ) was one of the first data centers, which established a peer-review like data publication procedure resulting in DataCite DOIs. Data in the long-term archive (LTA) is diligently reviewed by data managers and data authors to grant high quality and widely reusability of the published data. This traditional data publication procedure for LTA data bearing DOIs is very time consuming especially for WDCC's high data volumes of climate model data in the order of multiple TBytes. Data is shared with project members and selected scientists months before the data is long-term archived. The scientific community analyses and thus reviews the data leading to data quality improvements. Scientists wish to cite these unstable data in scientific publications before the long-term archiving and the thorough data review process are finalized. A concept for early preprint DOIs for shared but not yet long-term archived data is presented. Requirements on data documentation, persistence and quality and use cases for preprint DOIs within the data life-cycle are discussed as well as questions of how to document the differences of the two DOI types and how to relate them to each other with the recommendation to use LTA DOIs in citations. WDCC wants to offer an additional user service for early citations of data of basic quality without compromising the LTA DOIs, i.e. WDCC's standard DOIs, as trustworthy indicator for high quality data. Referencing Links: World Data Center for Climate (WDCC): http://www.wdc-climate.de German Climate Computing Center (DKRZ): http://www.dkrz.de DataCite: http://datacite.org

  18. Diffuse sky radiation influences the relationship between canopy PRI and shadow fraction

    NASA Astrophysics Data System (ADS)

    Mõttus, Matti; Takala, Tuure L. H.; Stenberg, Pauline; Knyazikhin, Yuri; Yang, Bin; Nilson, Tiit

    2015-07-01

    The Photochemical Reflectance Index (PRI) of green leaves is an indicator of photosynthetic downregulation: when the photosynthetic apparatus is close to the saturation limit, PRI becomes dependent on light conditions. Therefore, by measuring the PRI of leaves under different local irradiance conditions, it should be possible to determine the saturation level of the leaves and obtain information on the light use efficiency (LUE) of a vegetation canopy. The dependence of PRI on the ratio of sunlit to shaded foliage (quantified by the canopy shadow fraction) in the field of view of an instrument has been used to remotely measure canopy LUE on clear days. However, besides photosynthetic downregulation, the dependence of canopy PRI on shadow fraction is affected by the blue sky radiation caused by scattering in the atmosphere. To quantify this effect on remotely sensed PRI, we present the underlying definitions relating leaf and canopy PRI and perform the required calculations for typical midsummer conditions in Central Finland. We demonstrate that the effect of blue sky radiation on the variation of PRI with canopy shadow fraction is similar in shape and magnitude to that of LUE variations reported in literature.

  19. 75 FR 36357 - Clarification on the Procedure for Seeking Review of a Finding of a Substantial New Question of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ...The United States Patent and Trademark Office (USPTO) is clarifying the procedure for seeking review of a determination that a substantial new question of patentability (SNQ) has been raised in an ex parte reexamination proceeding. This notice clarifies that while issues related to a SNQ determination are procedural, the Chief Judge of the Board of Patent Appeals and Interferences (BPAI) has......

  20. 36 CFR 1260.42 - What are the procedures for agency personnel to review records at a NARA facility?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... damage to archival materials. See 36 CFR part 1254 for more information on acceptable equipment. ... handling of archival materials. (b) Agency reviewers must: (1) Follow NARA security regulations and abide by NARA procedures for handling archival materials; (2) Follow NARA procedures for identifying...

  1. Review of edgematchimg procedures for digital cartographic data used in Geographic Information Systems (GIS)

    USGS Publications Warehouse

    Nebert, D.D.

    1989-01-01

    In the process of developing a continuous hydrographic data layer for water resources applications in the Pacific Northwest, map-edge discontinuities in the U.S. Geological Survey 1:100 ,000-scale digital data that required application of computer-assisted edgematching procedures were identified. The spatial data sets required by the project must have line features that match closely enough across map boundaries to ensure full line topology when adjacent files are joined by the computer. Automated edgematching techniques are evaluated as to their effects on positional accuracy. Interactive methods such as selective node-matching and on-screen editing are also reviewed. Interactive procedures complement automated methods by allowing supervision of edgematching in a cartographic and hydrologic context. Common edge conditions encountered in the preparation of the Northwest Rivers data base are described, as are recommended processing solutions. Suggested edgematching procedures for 1:100,000-scale hydrography data are included in an appendix to encourage consistent processing of this theme on a national scale. (USGS)

  2. Cold and compression in the management of musculoskeletal injuries and orthopedic operative procedures: a narrative review

    PubMed Central

    Block, Jon E

    2010-01-01

    Cold and compression are routinely applied immediately after acute injury or following surgery to alleviate pain, reduce swelling and speed functional recovery. The objective of this literature review is to describe the published clinical findings regarding combined cold and compression therapy in the management of musculoskeletal injuries and after orthopedic operative procedures. Of 33 potential articles triaged, the findings of 21 randomized controlled trials were assessed and summarized. The findings reported by these 21 studies were largely subjective pain outcomes and, to a lesser degree, swelling and range of motion, and were inconsistent and divergent, making it difficult to recommend the most appropriate, effective clinical application of cold and compression. Further, 18 of the 21 reported studies evaluated cold and static compression, where the extent and duration of the compression was not uniform within or across studies. Operative procedures may offer a more controlled environment for rigorous investigations. However, such studies must be powered sufficiently to account for variations in surgical procedure that could affect outcomes. More uniform operative procedures, such as total knee arthroplasty, represent a well circumscribed intervention for studying the clinical utility of cold compression therapy because the operative technique is standardized, surgical tissue damage is extensive, intraoperative blood loss is high, and post-operative edema and pain are severe. Findings from randomized controlled trials of knee arthroplasty generally showed cold compression therapy provides better outcomes such as pain relief than alternative interventions. While the effects of cold and static compression are clearly better than no treatment, they do not appear to be directly additive. PMID:24198548

  3. 21 CFR 56.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 56.110 Section 56.110 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL INSTITUTIONAL REVIEW BOARDS IRB Functions...

  4. 21 CFR 56.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 56.110 Section 56.110 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL INSTITUTIONAL REVIEW BOARDS IRB Functions...

  5. 21 CFR 56.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 56.110 Section 56.110 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL INSTITUTIONAL REVIEW BOARDS IRB Functions...

  6. A Meta-Analytic Review of the Cover-Copy-Compare and Variations of This Self-Management Procedure

    ERIC Educational Resources Information Center

    Joseph, Laurice M.; Konrad, Moira; Cates, Gary; Vajcner, Terra; Eveleigh, Elisha; Fishley, Katelyn M.

    2012-01-01

    Studies that examined copy-cover-compare (CCC) and variations of this procedure were reviewed and analyzed. This review revealed a substantial number of studies that validated the use of CCC across spelling and math skills and across students with and without disabilities. A meta-analysis of findings indicated that CCC and variations of this…

  7. 21 CFR 56.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 56.110 Section 56.110 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL INSTITUTIONAL REVIEW BOARDS IRB Functions...

  8. 75 FR 29996 - Review of MMS NEPA Policies, Practices, and Procedures for OCS Oil and Gas Exploration and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-28

    ... QUALITY Review of MMS NEPA Policies, Practices, and Procedures for OCS Oil and Gas Exploration and Development AGENCY: Council on Environmental Quality. ACTION: Notice of Review and Request for Public Comment. SUMMARY: On May 17, 2010, the Council on Environmental Quality (CEQ) informed the Department of...

  9. 15 CFR Supplement No. 5 to Part 744 - Procedures for End-User Review Committee Entity List Decisions

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Committee Entity List Decisions No. Supplement No. 5 to Part 744 Commerce and Foreign Trade Regulations... No. 5 to Part 744—Procedures for End-User Review Committee Entity List Decisions The End-User Review... submitting that proposal to the chairman. The ERC will vote on each proposal no later than 30 days after...

  10. 15 CFR Supplement No. 5 to Part 744 - Procedures for End-User Review Committee Entity List Decisions

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Committee Entity List Decisions No. Supplement No. 5 to Part 744 Commerce and Foreign Trade Regulations... No. 5 to Part 744—Procedures for End-User Review Committee Entity List Decisions The End-User Review... submitting that proposal to the chairman. The ERC will vote on each proposal no later than 30 days after...

  11. 5 CFR 1201.114 - Petition and cross petition for review-content and procedure.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... review include a petition for review, a cross petition for review, a response to a petition for review, a response to a cross petition for review, and a reply to a response to a petition for review. (1) A petition... petition for review. (3) A response to a petition for review and a cross petition for review may...

  12. 5 CFR 1201.114 - Petition and cross petition for review-content and procedure.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... review include a petition for review, a cross petition for review, a response to a petition for review, a response to a cross petition for review, and a reply to a response to a petition for review. (1) A petition... petition for review. (3) A response to a petition for review and a cross petition for review may...

  13. Correcting the relationship between PRI and shadow fraction for the blue sky effect

    NASA Astrophysics Data System (ADS)

    Mõttus, Matti

    2016-04-01

    The Photochemical Reflectance Index (PRI) is defined as the normalized difference ratio of leaf reflectance at two specific wavelengths in the green spectral region. Its value depends on the status of leaf carotenoid content, and especially that of the xanthophyll cycle pigments. Due to the dependence on the xanthophyll cycle, when the photosynthetic apparatus of green leaves is close to the saturation limit, their PRI becomes dependent on light conditions. Therefore, by measuring the PRI of leaves in the same canopy under different local irradiance conditions on a sunny day, it should be possible to determine the saturation level of the leaves. In turn, this gives information on the light use efficiency (LUE) of the vegetation canopy. The average light conditions of visible foliage elements are often quantified with the shadow fraction -- the fraction of visible foliage not lit by direct sunlight. The dependence of PRI on the shadow fraction has been used to remotely measure canopy LUE on clear days. Variations in shadow fraction have been achieved with multiangular measurement. However, besides photosynthetic downregulation, the dependence of canopy PRI on shadow fraction is affected by the blue sky radiation caused by scattering in the atmosphere. To quantify this effect on remotely sensed PRI, we present the underlying definitions relating leaf and canopy PRI and perform the required calculations for typical midsummer conditions in Central Finland. We demonstrate that the effect of blue sky radiation on the variation of PRI with canopy shadow fraction is similar in shape and magnitude to that of LUE variations reported in literature. Next, we propose a new method to assess these PRI variations in structured vegetation. We investiagate this blue sky effect on the PRI -- shadow fraction relationship with high spatial (60 cm) and spectral (9.8 nm) resolution airborne imaging spectroscopy data from Hyytiälä, Finland. We evaluate the spectral irradiance in

  14. ALPPS Procedure for Extended Liver Resections: A Single Centre Experience and a Systematic Review

    PubMed Central

    Vivarelli, Marco; Vincenzi, Paolo; Montalti, Roberto; Fava, Giammarco; Tavio, Marcello; Coletta, Martina; Vecchi, Andrea; Nicolini, Daniele; Agostini, Andrea; Ali Ahmed, Emad; Giovagnoni, Andrea; Mocchegiani, Federico

    2015-01-01

    Aim To report a single-centre experience with the novel Associating Liver Partition and Portal vein ligation for Staged hepatectomy (ALPPS) technique and systematically review the related literature. Methods Since January 2013, patients with extended primary or secondary liver tumors whose future liver remnant (FLR) was considered too small to allow hepatic resection were prospectively assessed for the ALPPS procedure. A systematic literature search was performed using PubMed, Scopus and the Cochrane Library Central. Results Until July 2014 ALPPS was completed in 9 patients whose mean age was 60±8 years. Indications for surgical resection were metastases from colorectal cancer in 3 cases, perihilar cholangiocarcinoma in 3 cases, intrahepatic cholangiocarcinoma in 2 cases and hepatocellular carcinoma without chronic liver disease in 1 case. The calculated FLR volume was 289±122 mL (21.1±5.5%) before ALPPS-1 and 528±121 mL (32.2±5.7%) before ALLPS-2 (p<0.001). The increase in FLR between the two procedures was 96±47% (range: 24–160%, p<0.001). Additional interventions were performed in 4 cases: 3 patients underwent Roux-en-Y hepaticojejunostomy, and one case underwent wedge resection of a residual tumor in the FLR. The average time between the first and second step of the procedure was 10.8±2.9 days. The average hospital stay was 24.1±13.3 days. There was 1 postoperative death due to hepatic failure in the oldest patient of this series who had a perihilar cholangiocarcinoma and concomitant liver fibrosis; 11 complications occurred in 6 patients, 4 of whom had grade III or above disease. After a mean follow-up of 17.1±8.5 months, the overall survival was 89% at 3–6 and 12 months. The recurrence-free survival was 100%, 87.5% and 75% at 3-6-12 months respectively. The literature search yielded 148 articles, of which 22 articles published between 2012 and 2015 were included in this systematic review. Conclusion The ALPPS technique effectively increased the

  15. Non-Respiratory Indications for Polysomnography and Related Procedures in Children: An Evidence-Based Review

    PubMed Central

    Kotagal, Suresh; Nichols, Cynthia D.; Grigg-Damberger, Madeleine M.; Marcus, Carole L.; Witmans, Manisha B.; Kirk, Valerie G.; D'Andrea, Lynn A.; Hoban, Timothy F.

    2012-01-01

    Objective: This evidence-based review provides a systematic and comprehensive review of the literature regarding the utility of polysomnography for the evaluation of non-respiratory sleep disorders in children including hypersomnias, parasomnias, sleep-related movement disorders, and sleep in other special populations. Methods: A task force of pediatric sleep medicine experts performed a systematic review of the literature regarding the use of polysomnography for non-respiratory sleep disorders in children. They identified and graded 76 papers as evidence. Results: The main results include (1) polysomnography combined with the multiple sleep latency test is useful for evaluating disorders of excessive somnolence to objectively quantify sleepiness. The results have to be interpreted with consideration of the pubertal stage and regularity of the sleep patterns of the child; (2) polysomnography is indicated in children with parasomnias or sleep related movement disorders who have a high likelihood of having obstructive sleep apnea (OSA); (3) polysomnography is not routinely indicated in children with enuresis unless there is a high likelihood of OSA; (4) polysomnography can be helpful in evaluating children with restless legs syndrome (RLS) and when periodic limb movement disorder (PLMD) is suspected. Conclusions: These findings suggest that, in children with non-respiratory sleep disorders, polysomnography should be a part of a comprehensive sleep evaluation in selected circumstances to determine the nature of the events in more detail or when the suspicion of OSA is relatively high. Citation: Kotagal S; Nichols CD; Grigg-Damberger MM; Marcus CL; Witmans MB; Kirk VG; D'Andrea LA; Hoban TF. Non-respiratory indications for polysomnography and related procedures in children: an evidence-based review. SLEEP 2012;35(11):1451-1466. PMID:23115394

  16. Lung radiofrequency and microwave ablation: a review of indications, techniques and post-procedural imaging appearances

    PubMed Central

    Jennings, P E

    2015-01-01

    Lung ablation can be used to treat both primary and secondary thoracic malignancies. Evidence to support its use, particularly for metastases from colonic primary tumours, is now strong, with survival data in selected cases approaching that seen after surgery. Because of this, the use of ablative techniques (particularly thermal ablation) is growing and the Royal College of Radiologists predict that the number of patients who could benefit from such treatment may reach in excess of 5000 per year in the UK. Treatment is often limited to larger regional centres, and general radiologists often have limited awareness of the current indications and the techniques involved. Furthermore, radiologists without any prior experience are frequently expected to interpret post-treatment imaging, often performed in the context of acute complications, which have occurred after discharge. This review aims to provide an overview of the current indications for pulmonary ablation, together with the techniques involved and the range of post-procedural appearances. PMID:25465192

  17. Xenogeneic collagen matrix for periodontal plastic surgery procedures: a systematic review and meta-analysis.

    PubMed

    Atieh, M A; Alsabeeha, N; Tawse-Smith, A; Payne, A G T

    2016-08-01

    Several clinical trials describe the effectiveness of xenogeneic collagen matrix (XCM) as an alternative option to surgical mucogingival procedures for the treatment of marginal tissue recession and augmentation of insufficient zones of keratinized tissue (KT). The aim of this systematic review and meta-analysis was to evaluate the clinical and patient-centred outcomes of XCM compared to other mucogingival procedures. Applying guidelines of the Preferred Reporting Items for Systematic Reviews and Meta analyses statement, randomized controlled trials were searched for in electronic databases and complemented by hand searching. The risk of bias was assessed using the Cochrane Collaboration's Risk of Bias tool and data were analysed using statistical software. A total of 645 studies were identified, of which, six trials were included with 487 mucogingival defects in 170 participants. Overall meta-analysis showed that connective tissue graft (CTG) in conjunction with the coronally advanced flap (CAF) had a significantly higher percentage of complete/mean root coverage and mean recession reduction than XCM. Insufficient evidence was found to determine any significant differences in width of KT between XCM and CTG. The XCM had a significantly higher mean root coverage, recession reduction and gain in KT compared to CAF alone. No significant differences in patient's aesthetic satisfaction were found between XCM and CTG, except for postoperative morbidity in favour of XCM. Operating time was significantly reduced with the use of XCM compared with CTG but not with CAF alone. There is no evidence to demonstrate the effectiveness of XCM in achieving greater root coverage, recession reduction and gain in KT compared to CTG plus CAF. Superior short-term results in treating root coverage compared with CAF alone are possible. There is limited evidence that XCM may improve aesthetic satisfaction, reduce postoperative morbidity and shorten the operating time. Further long

  18. Remote cerebellar hemorrhage after spinal procedures (part 2): a systematic review.

    PubMed

    Sturiale, Carmelo Lucio; Rossetto, Marta; Ermani, Mario; Baro, Valentina; Volpin, Francesco; Milanese, Laura; Denaro, Luca; d'Avella, Domenico

    2016-07-01

    A remote cerebellar hemorrhage (RCH) is a spontaneous bleeding in the posterior fossa, which can be rarely observed as a complication of spine surgery. As well as for RCH reported after supratentorial procedures, it shows a characteristic bleeding pattern defined "zebra sign". Nowadays, RCH pathophysiology still remains unknown. We performed a comprehensive review, collecting all cases of RCH after spine surgery reported in literature in order to identify the procedures most frequently associated with RCH and the possible risk factors. We assessed percentages of incidence and 95 % confidence interval of all demographic, neuroradiological, and clinical features. Univariate and multivariate analyses were used to evaluate their association with outcome. We included 44 articles reporting 57 patients with mean age of 57.6 ± 13.9 years and a male/female ratio of 23/34. A RCH was more frequently reported as a complication of decompressive procedures for spinal canal stenosis, particularly when associated with instrumented fusion, followed by spinal tumor debulking and disc herniation removal. In the majority of cases, RCH occurrence was characterized by progressive impairment of consciousness, whereas some patients complained non-specific symptoms. Coagulation disorders, hypertension, and placement of postoperative subfascial drainages were the most frequently reported risk factors. The occurrence of intraoperative dural lesions was described in about 93 % of patients. Zebra sign was the most common bleeding pattern (about 43 % of cases) followed by parenchymal hematoma (37.5 %) and mixed hemorrhage (about 20 %). Impairment of consciousness at clinical onset and intake of anticoagulants/antiplatelets appeared associated with poor outcome at univariate analysis. However, more than 75 % of patients showed a good outcome and a RCH often appeared as a benign and self-limiting condition, which usually did not require surgical treatment, but only prolonged clinical

  19. Improved enteral tolerance following step procedure: systematic literature review and meta-analysis.

    PubMed

    Fernandes, Melissa A; Usatin, Danielle; Allen, Isabel E; Rhee, Sue; Vu, Lan

    2016-10-01

    Surgical management of children with short bowel syndrome (SBS) changed with the introduction of the serial transverse enteroplasty procedure (STEP). We conducted a systematic review and meta-analysis using MEDLINE and SCOPUS to determine if children with SBS had improved enteral tolerance following STEP. Studies were included if information about a child's pre- and post-STEP enteral tolerance was provided. A random effects meta-analysis provided a summary estimate of the proportion of children with enteral tolerance increase following STEP. From 766 abstracts, seven case series involving 86 children were included. Mean percent tolerance of enteral nutrition improved from 35.1 to 69.5. Sixteen children had no enteral improvement following STEP. A summary estimate showed that 87 % (95 % CI 77-95 %) of children who underwent STEP had an increase in enteral tolerance. Compilation of the literature supports the belief that SBS subjects' enteral tolerance improves following STEP. Enteral nutritional tolerance is a measure of efficacy of STEP and should be presented as a primary or secondary outcome. By standardizing data collection on children undergoing STEP procedure, better determination of nutritional benefit from STEP can be ascertained. PMID:27461428

  20. Peroral endoscopic myotomy—initial experience with anesthetic management of 24 procedures and systematic review

    PubMed Central

    Goudra, Basavana; Singh, Preet Mohinder; Gouda, Gowri; Sinha, Ashish C.

    2016-01-01

    Background: Peroral endoscopic myotomy (POEM) is a novel method of treating achalasia of the esophagus. Very little data are available to guide the anesthesia providers caring for these patients. The anesthetic challenges are primarily related to the risk of pulmonary aspiration. There is also a potential risk of pneumomediastinum, pneumoperitoneum, subcutaneous, or submucosal emphysema, as a result of carbon dioxide tracking into the soft tissues surrounding the esophagus and lower esophageal sphincter. Methods: In this retrospective study, electronic charts of 24 patients who underwent POEM over 18 months were reviewed. Demographic data, fasting status, relevant aspiration risks, anesthetic technique, and postoperative care measures were extracted. Results: Fasting times for both solids and liquids were variable. None of the patients underwent preprocedural esophageal emptying. Standard induction and intubation were performed in 16, rapid sequence induction (RSI) with cricoid pressure in seven, and modified rapid sequence without application of cricoid pressure in one of the patients. One of the patients aspirated at induction, and the procedure was aborted. However, the procedure was performed successfully after a few weeks, this time a RSI with cricoid pressure was chosen. Conclusion: As there are no guidelines for the perioperative management of patients presenting for POEM presently, certain recommendations can be made. Preprocedural esophageal emptying should be considered in patients considered as high-risk, although cultural factors might preclude such an approach. Induction and intubation in a semi-reclining position might be useful. Although debatable, use of RSI with cricoid pressure should be strongly considered. PMID:27212764

  1. Submental/Transmylohyoid Route for Endotracheal Intubation in Maxillofacial Surgical Procedures: A Review

    PubMed Central

    Prakash, V Jeevan; Chakravarthy, Chitra; Attar, Abdul Hameed

    2014-01-01

    Patients with severe panfacial injuries usually require long-term airway management. Nasal intubation may be contraindicated in case of nasoorbitoethmoidal fractures and also there may be a need for intraoperative and short-term postoperative intermaxillary fixation to achieve optimum reduction of fractures. The need for unobstructed access to the perinasal area during bimaxillary orthognathic procedures is felt many a time and to avoid a tracheostomy with its attending morbidity, many techniques have evolved that involve a submandibular/transmylohyoid or submental approach for temporary oroendotracheal intubation. In this article, we present our experience of patients by using submental/transmylohyoid route for endotracheal intubation. technique gives the surgeon and the anesthetist comfortable control over their respective domains, is easy to learn and implement in the operating protocol with no added costs. How to cite the article: Prakash VJ, Chakravarthy C, Attar AH. Submental/transmylohyoid route for endotracheal intubation in maxillofacial surgical procedures: A review. J Int Oral Health 2014;6(3):125-8. PMID:25083048

  2. Monitoring seasonal and diurnal changes in photosynthetic pigments with automated PRI and NDVI sensors

    NASA Astrophysics Data System (ADS)

    Gamon, J. A.; Kovalchuck, O.; Wong, C. Y. S.; Harris, A.; Garrity, S. R.

    2015-07-01

    The vegetation indices normalized difference vegetation index (NDVI) and photochemical reflectance index (PRI) provide indicators of pigmentation and photosynthetic activity that can be used to model photosynthesis from remote sensing with the light-use-efficiency model. To help develop and validate this approach, reliable proximal NDVI and PRI sensors have been needed. We tested new NDVI and PRI sensors, "spectral reflectance sensors" (SRS sensors; recently developed by Decagon Devices, during spring activation of photosynthetic activity in evergreen and deciduous stands. We also evaluated two methods of sensor cross-calibration - one that considered sky conditions (cloud cover) at midday only, and another that also considered diurnal sun angle effects. Cross-calibration clearly affected sensor agreement with independent measurements, with the best method dependent upon the study aim and time frame (seasonal vs. diurnal). The seasonal patterns of NDVI and PRI differed for evergreen and deciduous species, demonstrating the complementary nature of these two indices. Over the spring season, PRI was most strongly influenced by changing chlorophyll : carotenoid pool sizes, while over the diurnal timescale, PRI was most affected by the xanthophyll cycle epoxidation state. This finding demonstrates that the SRS PRI sensors can resolve different processes affecting PRI over different timescales. The advent of small, inexpensive, automated PRI and NDVI sensors offers new ways to explore environmental and physiological constraints on photosynthesis, and may be particularly well suited for use at flux tower sites. Wider application of automated sensors could lead to improved integration of flux and remote sensing approaches for studying photosynthetic carbon uptake, and could help define the concept of contrasting vegetation optical types.

  3. Monitoring seasonal and diurnal changes in photosynthetic pigments with automated PRI and NDVI sensors

    NASA Astrophysics Data System (ADS)

    Gamon, J. A.; Kovalchuk, O.; Wong, C. Y. S.; Harris, A.; Garrity, S. R.

    2015-02-01

    The vegetation indices normalized difference vegetation index (NDVI) and photochemical reflectance index (PRI) provide indicators of pigmentation and photosynthetic activity that can be used to model photosynthesis from remote sensing with the light-use efficiency model. To help develop and validate this approach, reliable proximal NDVI and PRI sensors have been needed. We tested new NDVI and PRI sensors, "SRS" sensors recently developed by Decagon Devices, during spring activation of photosynthetic activity in evergreen and deciduous stands. We also evaluated two methods of sensor cross-calibration, one that considered sky conditions (cloud cover) at midday only, and the other that also considered diurnal sun angle effects. Cross-calibration clearly affected sensor agreement with independent measurements, with the best method dependent upon the study aim and time frame (seasonal vs. diurnal). The seasonal patterns of NDVI and PRI differed for evergreen and deciduous species, demonstrating the complementary nature of these two indices. Over the spring season, PRI was most strongly influenced by changing chlorophyll : carotenoid pool sizes, while over the diurnal time scale PRI was most affected by the xanthophyll cycle epoxidation state. This finding demonstrates that the SRS PRI sensors can resolve different processes affecting PRI over different time scales. The advent of small, inexpensive, automated PRI and NDVI sensors offers new ways to explore environmental and physiological constraints on photosynthesis, and may be particularly well-suited for use at flux tower sites. Wider application of automated sensors could lead to improved integration of flux and remote sensing approaches to studying photosynthetic carbon uptake, and could help define the concept of contrasting vegetation optical types.

  4. Regulating Behavioral Procedures for Individuals with Handicaps: Review of State Department Standards.

    ERIC Educational Resources Information Center

    Morgan, Robert L.; And Others

    1991-01-01

    This study analyzed and compared the behavioral procedure standards of 39 state departments of special education and 41 state departments of developmental disabilities/mental retardation. Results are discussed in terms of systematic monitoring of procedures, staff training, procedures to increase behavior, prohibiting/restricting procedure use,…

  5. Shoulder Structure and Function Following the Modified Latarjet Procedure: A Clinical and Radiological Review

    PubMed Central

    Garewal, Devinder; Evans, Mathew; Taylor, David; Hoy, Gregory A.; Barwood, Shane; Connell, David

    2013-01-01

    Background To evaluate the clinical and radiological outcomes of the modified Latarjet procedure for traumatic, antero-inferior glenohumeral joint instability. Methods Case series were used with a mean follow-up of 21.3 months for clinical and radiological review and 47.2 months for recurrent instability. Shoulder function was evaluated by clinical examination and validated shoulder scales: Western Ontario Shoulder Stability Index (WOSI), Melbourne Instability Shoulder Score (MISS) and l'Insalata Shoulder Questionnaire. Shoulder structure was evaluated by computed tomography. Results Thirty-two cases were enrolled (mean age 27.0 years). One patient reported a redislocation during the follow-up period. Clinical examination revealed that the median external rotation (at 0° and 90° abduction) was reduced on the operative side by 7.5° (p < 0.01) and 10° (p < 0.001), respectively. Subjective shoulder function was good. Mean (SD) scores on the WOSI, MISS and l'Insalata scales were 78.0 (19.7), 75.8 (11.5) and 89.3 (9.9), respectively. No loss of subscapularis strength was identified (p > 0.05). Radiological evaluation revealed a mean (SD) pre-operative glenoid surface area loss of 169.5 (48.5) mm2 reconstituted surgically by a bone block of 225.4 (73.8) mm2. Subscapularis muscle bulk was reduced on the operative side, above the level of the muscle split (p < 0.05). Conclusions The Latarjet procedure reliably restores lost glenoid surface area, shoulder stability, strength and function. A small loss of external rotation is expected and related to altered subscapularis anatomy.

  6. Music used as anti-anxiety intervention for patients during outpatient procedures: A review of the literature.

    PubMed

    Daniel, Eva

    2016-02-01

    Numerous patients experience anxiety before minor medical procedures [1]. Because patients' experiences are highly individualized, their distress may range from mild to moderate. For a decade, music-based complementary therapy has received increased attention because of the therapeutic and healing environment it creates for patients undergoing invasive procedures [13]. The purpose of this structured literature review is to assess the current evidence regarding the effectiveness of music as an intervention that decreases anxiety for patients undergoing minor medical procedures in outpatient healthcare settings. PMID:26850800

  7. mirEX: a platform for comparative exploration of plant pri-miRNA expression data.

    PubMed

    Bielewicz, Dawid; Dolata, Jakub; Zielezinski, Andrzej; Alaba, Sylwia; Szarzynska, Bogna; Szczesniak, Michal W; Jarmolowski, Artur; Szweykowska-Kulinska, Zofia; Karlowski, Wojciech M

    2012-01-01

    mirEX is a comprehensive platform for comparative analysis of primary microRNA expression data. RT-qPCR-based gene expression profiles are stored in a universal and expandable database scheme and wrapped by an intuitive user-friendly interface. A new way of accessing gene expression data in mirEX includes a simple mouse operated querying system and dynamic graphs for data mining analyses. In contrast to other publicly available databases, the mirEX interface allows a simultaneous comparison of expression levels between various microRNA genes in diverse organs and developmental stages. Currently, mirEX integrates information about the expression profile of 190 Arabidopsis thaliana pri-miRNAs in seven different developmental stages: seeds, seedlings and various organs of mature plants. Additionally, by providing RNA structural models, publicly available deep sequencing results, experimental procedure details and careful selection of auxiliary data in the form of web links, mirEX can function as a one-stop solution for Arabidopsis microRNA information. A web-based mirEX interface can be accessed at http://bioinfo.amu.edu.pl/mirex. PMID:22013167

  8. Structure and Function of the PriC DNA Replication Restart Protein.

    PubMed

    Wessel, Sarah R; Cornilescu, Claudia C; Cornilescu, Gabriel; Metz, Alice; Leroux, Maxime; Hu, Kaifeng; Sandler, Steven J; Markley, John L; Keck, James L

    2016-08-26

    Collisions between DNA replication complexes (replisomes) and barriers such as damaged DNA or tightly bound protein complexes can dissociate replisomes from chromosomes prematurely. Replisomes must be reloaded under these circumstances to avoid incomplete replication and cell death. Bacteria have evolved multiple pathways that initiate DNA replication restart by recognizing and remodeling abandoned replication forks and reloading the replicative helicase. In vitro, the simplest of these pathways is mediated by the single-domain PriC protein, which, along with the DnaC helicase loader, can load the DnaB replicative helicase onto DNA bound by the single-stranded DNA (ssDNA)-binding protein (SSB). Previous biochemical studies have identified PriC residues that mediate interactions with ssDNA and SSB. However, the mechanisms by which PriC drives DNA replication restart have remained poorly defined due to the limited structural information available for PriC. Here, we report the NMR structure of full-length PriC from Cronobacter sakazakii PriC forms a compact bundle of α-helices that brings together residues involved in ssDNA and SSB binding at adjacent sites on the protein surface. Disruption of these interaction sites and of other conserved residues leads to decreased DnaB helicase loading onto SSB-bound DNA. We also demonstrate that PriC can directly interact with DnaB and the DnaB·DnaC complex. These data lead to a model in which PriC acts as a scaffold for recruiting DnaB·DnaC to SSB/ssDNA sites present at stalled replication forks. PMID:27382050

  9. 40 CFR 26.1110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 26.1110 Section 26.1110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROTECTION OF HUMAN SUBJECTS Basic Ethical Requirements...

  10. 38 CFR 16.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 16.110 Section 16.110 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS PROTECTION OF HUMAN SUBJECTS §...

  11. 45 CFR 46.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 46.110 Section 46.110 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PROTECTION OF HUMAN SUBJECTS Basic HHS Policy for...

  12. 15 CFR 27.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 27.110 Section 27.110 Commerce and Foreign Trade Office of the Secretary of Commerce PROTECTION OF HUMAN SUBJECTS § 27.110 Expedited...

  13. 40 CFR 26.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 26.110 Section 26.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROTECTION OF HUMAN SUBJECTS Basic EPA Policy for...

  14. 32 CFR 219.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 219.110 Section 219.110 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PROTECTION OF...

  15. 42 CFR 137.365 - What is the procedure for the Secretary's review and approval of project planning and design...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Secretary in Establishing and Implementing Construction Project Agreements § 137.365 What is the procedure... planning standards identified in the construction project agreement. The Secretary shall review and approve design documents for general compliance with requirements of the construction project agreement. (b)...

  16. 31 CFR 1.27 - Procedures for amendment of records pertaining to individuals-format, agency review and appeal...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Procedures for amendment of records pertaining to individuals-format, agency review and appeal from initial adverse agency determination. 1.27 Section 1.27 Money and Finance: Treasury Office of the Secretary of the Treasury DISCLOSURE OF...

  17. 42 CFR Appendix to Subpart G of... - Interim Procedures and Criteria for Review by Health Systems Agencies of Applications Under...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    .... The relationship of the health services provided by the facility to the existing health care system of... purposes of this paragraph, a “person directly affected by the review” is as defined in 42 CFR 122.306 (a... 42 Public Health 1 2010-10-01 2010-10-01 false Interim Procedures and Criteria for Review...

  18. 42 CFR Appendix to Subpart G of... - Interim Procedures and Criteria for Review by Health Systems Agencies of Applications Under...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .... The relationship of the health services provided by the facility to the existing health care system of... purposes of this paragraph, a “person directly affected by the review” is as defined in 42 CFR 122.306 (a... 42 Public Health 1 2014-10-01 2014-10-01 false Interim Procedures and Criteria for Review...

  19. 42 CFR Appendix to Subpart G of... - Interim Procedures and Criteria for Review by Health Systems Agencies of Applications Under...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    .... The relationship of the health services provided by the facility to the existing health care system of... purposes of this paragraph, a “person directly affected by the review” is as defined in 42 CFR 122.306 (a... 42 Public Health 1 2011-10-01 2011-10-01 false Interim Procedures and Criteria for Review...

  20. 42 CFR Appendix to Subpart G of... - Interim Procedures and Criteria for Review by Health Systems Agencies of Applications Under...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .... The relationship of the health services provided by the facility to the existing health care system of... purposes of this paragraph, a “person directly affected by the review” is as defined in 42 CFR 122.306 (a... 42 Public Health 1 2012-10-01 2012-10-01 false Interim Procedures and Criteria for Review...

  1. 42 CFR Appendix to Subpart G of... - Interim Procedures and Criteria for Review by Health Systems Agencies of Applications Under...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    .... The relationship of the health services provided by the facility to the existing health care system of... purposes of this paragraph, a “person directly affected by the review” is as defined in 42 CFR 122.306 (a... 42 Public Health 1 2013-10-01 2013-10-01 false Interim Procedures and Criteria for Review...

  2. 28 CFR 46.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 46.110 Section 46.110 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PROTECTION OF...

  3. 40 CFR 26.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 26.110 Section 26.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROTECTION OF HUMAN SUBJECTS Basic EPA Policy for...

  4. 40 CFR 26.1110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 26.1110 Section 26.1110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROTECTION OF HUMAN SUBJECTS Basic Ethical Requirements...

  5. 40 CFR 26.1110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 26.1110 Section 26.1110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROTECTION OF HUMAN SUBJECTS Basic Ethical Requirements...

  6. 16 CFR 1028.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 1028.110 Section 1028.110 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL PROTECTION OF HUMAN SUBJECTS § 1028.110 Expedited...

  7. 14 CFR 1230.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 1230.110 Section 1230.110 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PROTECTION OF HUMAN SUBJECTS (Eff. until 2-14-14) §...

  8. 38 CFR 16.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 16.110 Section 16.110 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS PROTECTION OF HUMAN SUBJECTS §...

  9. 45 CFR 46.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 46.110 Section 46.110 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PROTECTION OF HUMAN SUBJECTS Basic HHS Policy for...

  10. 38 CFR 16.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 16.110 Section 16.110 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS PROTECTION OF HUMAN SUBJECTS §...

  11. 40 CFR 26.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 26.110 Section 26.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROTECTION OF HUMAN SUBJECTS Basic EPA Policy for...

  12. 16 CFR 1028.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 1028.110 Section 1028.110 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL PROTECTION OF HUMAN SUBJECTS § 1028.110 Expedited...

  13. 34 CFR 97.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 97.110 Section 97.110 Education Office of the Secretary, Department of Education PROTECTION OF HUMAN SUBJECTS Federal Policy for the Protection of Human Subjects...

  14. 38 CFR 16.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2014-07-01 2014-07-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 16.110 Section 16.110 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS PROTECTION OF HUMAN SUBJECTS §...

  15. 12 CFR 563.580 - What standards and procedures will govern OTS review of the substance of my notice?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false What standards and procedures will govern OTS review of the substance of my notice? 563.580 Section 563.580 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY SAVINGS ASSOCIATIONS-OPERATIONS Notice of Change of Director or Senior Executive Officer § 563.580 What...

  16. 14 CFR 1230.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 1230.110 Section 1230.110 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PROTECTION...

  17. 14 CFR 1230.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 1230.110 Section 1230.110 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PROTECTION...

  18. 14 CFR 1230.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 1230.110 Section 1230.110 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PROTECTION...

  19. 14 CFR 1230.110 - Expedited review procedures for certain kinds of research involving no more than minimal risk...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Expedited review procedures for certain kinds of research involving no more than minimal risk, and for minor changes in approved research. 1230.110 Section 1230.110 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PROTECTION...

  20. 29 CFR 37.62 - What are the authority and procedures for conducting pre-approval compliance reviews?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true What are the authority and procedures for conducting pre-approval compliance reviews? 37.62 Section 37.62 Labor Office of the Secretary of Labor IMPLEMENTATION OF THE NONDISCRIMINATION AND EQUAL OPPORTUNITY PROVISIONS OF THE WORKFORCE INVESTMENT ACT OF 1998...

  1. The effectiveness of hypnosis for reducing procedure-related pain in children and adolescents: a comprehensive methodological review.

    PubMed

    Accardi, Michelle C; Milling, Leonard S

    2009-08-01

    A comprehensive, methodologically informed review of studies of the effectiveness of hypnosis for reducing procedure-related pain in children and adolescents is provided. To be included in the review, studies were required to use a between-subjects or mixed model design in which hypnosis was compared with a control condition or an alternative intervention in reducing the procedure-related pain of patients younger than age 19. An exhaustive search identified 13 studies satisfying these criteria. Hypnosis was consistently found to be more effective than control conditions in alleviating discomfort associated with bone marrow aspirations, lumbar punctures, voiding cystourethograms, the Nuss procedure, and post-surgical pain. Furthermore, hypnosis was as at least as effective as distraction. Three hypnotic interventions met criteria as a possibly efficacious empirically supported therapy for reducing post-surgical or lumbar puncture pain. Several other hypnotic interventions would have achieved the status of a possibly efficacious therapy had studies used a treatment manual. PMID:19255840

  2. Local anaesthesia for major general surgical procedures. A review of 116 cases over 12 years.

    PubMed Central

    Dennison, A.; Oakley, N.; Appleton, D.; Paraskevopoulos, J.; Kerrigan, D.; Cole, J.; Thomas, W. E.

    1996-01-01

    Between 1980 and 1992, 116 patients had either a simple mastectomy (32) or intra-abdominal procedures (84) under local anaesthesia (0.5-1% lignocaine with 1:200 000 adrenaline). A wide variety of general surgical procedures were feasible using only supplementary intravenous sedation (54%). Complications were uncommon and related to surgical procedure (three incorrect diagnoses, three procedures impossible) rather than the anaesthetic technique. There were no anaesthetic toxicity or postoperative problems. Local anaesthesia is extremely safe and facilitates larger surgical procedures than is generally appreciated. PMID:8871461

  3. Antibiotic Prophylaxis for Gynecologic Procedures prior to and during the Utilization of Assisted Reproductive Technologies: A Systematic Review

    PubMed Central

    Hutchinson, Anne P.; Lekovich, Jovana P.; Hobeika, Elie; Elias, Rony T.

    2016-01-01

    The use of assisted reproductive technologies (ART) has increased steadily. There has been a corresponding increase in the number of ART-related procedures such as hysterosalpingography (HSG), saline infusion sonography (SIS), hysteroscopy, laparoscopy, oocyte retrieval, and embryo transfer (ET). While performing these procedures, the abdomen, upper vagina, and endocervix are breached, leading to the possibility of seeding pelvic structures with microorganisms. Antibiotic prophylaxis is therefore important to prevent or treat any procedure-related infections. After careful review of the published literature, it is evident that routine antibiotic prophylaxis is generally not recommended for the majority of ART-related procedures. For transcervical procedures such as HSG, SIS, hysteroscopy, ET, and chromotubation, patients at risk for pelvic infections should be screened and treated prior to the procedure. Patients with a history of pelvic inflammatory disease (PID) or dilated fallopian tubes are at high risk for postprocedural infections and should be given antibiotic prophylaxis during procedures such as HSG, SIS, or chromotubation. Antibiotic prophylaxis is recommended prior to oocyte retrieval in patients with a history of endometriosis, PID, ruptured appendicitis, or multiple prior pelvic surgeries. PMID:27047692

  4. Efficacy Outcome Measures for Procedural Sedation Clinical Trials in Adults: An ACTTION Systematic Review.

    PubMed

    Williams, Mark R; McKeown, Andrew; Dexter, Franklin; Miner, James R; Sessler, Daniel I; Vargo, John; Turk, Dennis C; Dworkin, Robert H

    2016-01-01

    Successful procedural sedation represents a spectrum of patient- and clinician-related goals. The absence of a gold-standard measure of the efficacy of procedural sedation has led to a variety of outcomes being used in clinical trials, with the consequent lack of consistency among measures, making comparisons among trials and meta-analyses challenging. We evaluated which existing measures have undergone psychometric analysis in a procedural sedation setting and whether the validity of any of these measures support their use across the range of procedures for which sedation is indicated. Numerous measures were found to have been used in clinical research on procedural sedation across a wide range of procedures. However, reliability and validity have been evaluated for only a limited number of sedation scales, observer-rated pain/discomfort scales, and satisfaction measures in only a few categories of procedures. Typically, studies only examined 1 or 2 aspects of scale validity. The results are likely unique to the specific clinical settings they were tested in. Certain scales, for example, those requiring motor stimulation, are unsuitable to evaluate sedation for procedures where movement is prohibited (e.g., magnetic resonance imaging scans). Further work is required to evaluate existing measures for procedures for which they were not developed. Depending on the outcomes of these efforts, it might ultimately be necessary to consider measures of sedation efficacy to be procedure specific. PMID:26678470

  5. Delayed manifestation of bilateral scleral thinning after I-BRITE® procedure and review of literature for cosmetic eye-whitening procedures

    PubMed Central

    Moshirfar, Majid; McCaughey, Michael V; Fenzl, Carlton R; Santiago-Caban, Luis; Kramer, Gregory D; Mamalis, Nick

    2015-01-01

    Purpose To report a case of delayed-onset bilateral scleral thinning and calcium deposition following a cosmetic ocular-whitening procedure (I-BRITE®). Methods A 33-year-old male patient with a history of right-sided ptosis repair and left-sided anterior uveitis had previously undergone bilateral I-BRITE treatment for chronic conjunctival hyperemia. Four years after the procedure, the patient was referred to our institution with bilateral scleral thinning and overlying calcific depositions. A literature review was performed through PubMed from 1980 through 2014 using the search terms ‘cosmetic’, ‘ocular’, ‘conjunctivectomy’, ‘regional conjunctivectomy’, ‘I-BRITE’, ‘eye-whitening’, ‘scleritis’, ‘necrotizing scleritis’, ‘anterior uveitis’, ‘mitomycin C’, ‘5-fluorouracil’, and ‘bevacizumab’, along with associated cross-referencing from relevant articles. Results Examination of the patient revealed bilateral necrotizing scleritis within the nasal region of both eyes. Calcified plaques were also present within the areas of scleromalacia, along with epithelial defects demonstrated with fluorescein staining. Although evidence of previous intraocular inflammation was apparent within the left eye, there were no active signs of inflammation evident within either eye on initial presentation. Complication rates reported in the literature include: scleral thinning (1.8%), calcific plaque formation (2.9%), fibrovascular proliferation (13%), diplopia (1.2%), elevation of intraocular pressure (4.2%), and recurrence of conjunctival hyperemia (2.1%). Conclusion Cosmetic ocular whitening procedures have an attendant high complication rate, and have been associated with several adverse postoperative complications, which have in turn generated several reservations regarding the veritable benefit of the procedure. Many postsurgical complications may demonstrate delayed apparition, varying from several months to several years after primary

  6. Bi-directional processing of pri-miRNAs with branched terminal loops by Arabidopsis Dicer-like1

    PubMed Central

    Zhu, Hongliang; Zhou, Yuyi; Castillo-González, Claudia; Lu, Amber; Ge, Chunxiao; Zhao, Ying-Tao; Duan, Liusheng; Li, Zhaohu; Axtell, Michael J.; Wang, Xiu-Jie; Zhang, Xiuren

    2013-01-01

    miRNAs originate from primary transcripts (pri-miRNAs) with characteristic stem-loop structures. Accurate processing of pri-miRNAs is required for functional miRNAs. Here, using pri-miR166 family as a paradigm, we report the decisive role of pri-miRNA terminal loops in miRNA biogenesis. We found that multi-branched terminal loops in pri-miR166s substantially suppressed miR166 expression in vivo. Unlike canonical processing of pri-miRNAs, terminal-loop-branched (TLBed) pri-miRNAs can be processed by Dicer-like1 (DCL1) complexes bi-directionally: from base to loop and from loop to base, resulting in productive and abortive processing of miRNAs, respectively. In either case, DCL1 complexes canonically cut pri-miRNAs at a distance of 16-17 base pairs (bp) from a reference single-stranded loop region. DCL1 also adjusts processing sites toward an internal loop through its helicase domain. Thus, these results provide new insight into the poorly understood processing mechanism of pri-miRNAs with complicated secondary structures. PMID:23934148

  7. Structural and functional characterization of the CAP domain of pathogen-related yeast 1 (Pry1) protein.

    PubMed

    Darwiche, Rabih; Kelleher, Alan; Hudspeth, Elissa M; Schneiter, Roger; Asojo, Oluwatoyin A

    2016-01-01

    The production, crystal structure, and functional characterization of the C-terminal cysteine-rich secretory protein/antigen 5/pathogenesis related-1 (CAP) domain of pathogen-related yeast protein-1 (Pry1) from Saccharomyces cerevisiae is presented. The CAP domain of Pry1 (Pry1CAP) is functional in vivo as its expression restores cholesterol export to yeast mutants lacking endogenous Pry1 and Pry2. Recombinant Pry1CAP forms dimers in solution, is sufficient for in vitro cholesterol binding, and has comparable binding properties as full-length Pry1. Two crystal structures of Pry1CAP are reported, one with Mg(2+) coordinated to the conserved CAP tetrad (His208, Glu215, Glu233 and His250) in spacegroup I41 and the other without divalent cations in spacegroup P6122. The latter structure contains four 1,4-dioxane molecules from the crystallization solution, one of which sits in the cholesterol binding site. Both structures reveal that the divalent cation and cholesterol binding sites are connected upon dimerization, providing a structural basis for the observed Mg(2+)-dependent sterol binding by Pry1. PMID:27344972

  8. Structural and functional characterization of the CAP domain of pathogen-related yeast 1 (Pry1) protein

    PubMed Central

    Darwiche, Rabih; Kelleher, Alan; Hudspeth, Elissa M.; Schneiter, Roger; Asojo, Oluwatoyin A.

    2016-01-01

    The production, crystal structure, and functional characterization of the C-terminal cysteine-rich secretory protein/antigen 5/pathogenesis related-1 (CAP) domain of pathogen-related yeast protein-1 (Pry1) from Saccharomyces cerevisiae is presented. The CAP domain of Pry1 (Pry1CAP) is functional in vivo as its expression restores cholesterol export to yeast mutants lacking endogenous Pry1 and Pry2. Recombinant Pry1CAP forms dimers in solution, is sufficient for in vitro cholesterol binding, and has comparable binding properties as full-length Pry1. Two crystal structures of Pry1CAP are reported, one with Mg2+ coordinated to the conserved CAP tetrad (His208, Glu215, Glu233 and His250) in spacegroup I41 and the other without divalent cations in spacegroup P6122. The latter structure contains four 1,4-dioxane molecules from the crystallization solution, one of which sits in the cholesterol binding site. Both structures reveal that the divalent cation and cholesterol binding sites are connected upon dimerization, providing a structural basis for the observed Mg2+-dependent sterol binding by Pry1. PMID:27344972

  9. Structural and functional characterization of the CAP domain of pathogen-related yeast 1 (Pry1) protein

    NASA Astrophysics Data System (ADS)

    Darwiche, Rabih; Kelleher, Alan; Hudspeth, Elissa M.; Schneiter, Roger; Asojo, Oluwatoyin A.

    2016-06-01

    The production, crystal structure, and functional characterization of the C-terminal cysteine-rich secretory protein/antigen 5/pathogenesis related-1 (CAP) domain of pathogen-related yeast protein-1 (Pry1) from Saccharomyces cerevisiae is presented. The CAP domain of Pry1 (Pry1CAP) is functional in vivo as its expression restores cholesterol export to yeast mutants lacking endogenous Pry1 and Pry2. Recombinant Pry1CAP forms dimers in solution, is sufficient for in vitro cholesterol binding, and has comparable binding properties as full-length Pry1. Two crystal structures of Pry1CAP are reported, one with Mg2+ coordinated to the conserved CAP tetrad (His208, Glu215, Glu233 and His250) in spacegroup I41 and the other without divalent cations in spacegroup P6122. The latter structure contains four 1,4-dioxane molecules from the crystallization solution, one of which sits in the cholesterol binding site. Both structures reveal that the divalent cation and cholesterol binding sites are connected upon dimerization, providing a structural basis for the observed Mg2+-dependent sterol binding by Pry1.

  10. 42 CFR 433.120 - Procedures for reduction of FFP after reapproval review.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Claims Processing and Information Retrieval Systems § 433.120 Procedures for reduction of FFP after... significance of the unsatisfactory conditions in overall mechanized claims processing and information...

  11. 76 FR 18571 - Notice of Submission of Proposed Information Collection to OMB; Environmental Review Procedures...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-04

    ... Procedures for Entities Assuming HUD Environmental Responsibilities AGENCY: Office of the Chief Information... Assuming HUD Environmental Responsibilities. OMB Approval Number: 2506-0087. Form Numbers:...

  12. Entonox® inhalation to reduce pain in common diagnostic and therapeutic outpatient urological procedures: a review of the evidence

    PubMed Central

    Young, A; Ismail, M; Papatsoris, AG; Barua, JM; Calleary, JG; Masood, J

    2012-01-01

    INTRODUCTION Entonox® (50% nitrous oxide and 50% oxygen; BOC Healthcare, Manchester, UK) is an analgesic and anxiolytic agent that is used to successfully reduce pain and anxiety during dental, paediatric and emergency department procedures. In this article we review the application and efficacy of Entonox® in painful local anaesthesia urological procedures by performing a systematic review of the literature. METHODS A MEDLINE® search was performed using the terms ‘nitrous oxide’, ‘Entonox’, ‘prostate biopsy’, ‘flexible cystoscopy’ and ‘extracorporeal shock wave lithotripsy’. English language publications of randomised studies were identified and reviewed. RESULTS The search yielded five randomised studies that investigated the clinical efficacy of Entonox® as an analgesic for day case urological procedures. Three randomised controlled trials (RCTs) investigated Entonox® in transrectal ultrasonography guided prostate biopsy. All three reported significant reductions in pain score in the Entonox® versus control groups. One RCT reported significant reduction in pain during male flexible cystoscopy in the Entonox® group compared with the control group. One RCT, which examined the use of Entonox® during extracorporeal shock wave lithotripsy, found its use significantly decreased the pain score compared with the control group and this was comparable to intravenous pethidine. CONCLUSIONS Evidence from varied adult and paediatric procedures has shown Entonox® to be an effective, safe and patient acceptable form of analgesia. All published studies of its use in urological day case procedures have found it to significantly reduce procedural pain. There is huge potential to use this cheap, safe, effective analgesic in our current practice. PMID:22524905

  13. Soft Tissue Infection Caused by Rapid Growing Mycobacterium following Medical Procedures: Two Case Reports and Literature Review

    PubMed Central

    Lin, Shih-Sen; Lee, Chin-Cheng

    2014-01-01

    Non-tubecrulosis mycobacterium infections were increasingly reported either pulmonary or extrapulmonary in the past decades. In Taiwan, we noticed several reports about the soft tissue infections caused by rapid growing mycobacterium such as Mycobacterium abscessus, Mycobacterium chelonae, on newspaper, magazines, or the multimedia. Most of them occurred after a plastic surgery, and medical or non-medical procedures. Here, we reported two cases of these infections following medical procedures. We also discussed common features and the clinical course of the disease, the characteristics of the infected site, and the treatment strategy. The literatures were also reviewed, and the necessity of the treatment guidelines was discussed. PMID:24882980

  14. Diurnal and Directional Responses of Chlorophyll Fluorescence and the PRI in a Cornfield

    NASA Technical Reports Server (NTRS)

    Middleton, Elizabeth; Cheng, Y. B.; Corp, L.; Campbell, P.; Kustas, W.

    2010-01-01

    Determining the health and vigor of vegetation using high spectral resolution remote sensing is an important goal which has application to monitoring agriculture and ecosystem productivity and carbon exchange. Two spectral indices used to assess whether vegetation is performing near-optimally or exhibiting symptoms of environmental stress (e.g., drought or nutrient deficiency, non-optimal temperatures, etc.) are the Photochemical Reflectance Index (PRI) and solar-induced red and far-red Chlorophyll Fluorescence (Fs). Both the PRI and Fs capture the dynamics of photoprotection mechanisms within green foliage: the PRI is based on the association of the reflected radiation in the green spectrum with the xanthophyll cycle, whereas Fs measures the emitted radiation in the red and far-red spectrum. Fs was determined from retrievals in the atmospheric oxygen absorption features centered at 688 and 760 nm using a modified Fraunhofer Line Depth (FLD) method. We previously demonstrated diurnal and seasonal PRI differences for sunlit vs. shaded foliage in a conifer forest canopy, as expressed in the hotspot and darkspot of the Bidirectional Reflectance Function (BRF). In a USDA-ARS experimental field site located in Beltsville, MD, USA, measurements were acquired over a corn crop from a nadir view in 2008 with an ASD FieldSpec Pro (Analytical Spectral Devices, Inc., Boulder, CO, USA) to study the behavior of the PRI for sunlit and shaded foliage as captured in reflectance variations associated with the BRF, in a I m tall canopy in the vegetative growth stage. Those observations were compared to simulations obtained from two radiative transfer models. Measurements were then acquired to examine whether the PRI and Fs were influenced by view zenith and azimuth geometries at different times of day. Those measurements were made in 2010 with the Ocean Optics USB4000 Miniature Fiber Optic Spectrometer (Ocean Optics Inc., Dunedin, Florida, USA) at several times during the day on

  15. Legal Office Procedures: Task Analyses. Competency-Based Education. Review Draft.

    ERIC Educational Resources Information Center

    Virginia Polytechnic Inst. and State Univ., Blacksburg.

    This task analysis guide is intended to help teachers and administrators develop instructional materials and implement competency-based education in a course on legal office procedures. Section 1 contains a validated task inventory for legal office procedures. For each task, applicable information pertaining to performance and enabling objectives,…

  16. REVIEW OF CURRENT RBC (ROTATING BIOLOGICAL CONTACTOR) PERFORMANCE AND DESIGN PROCEDURES

    EPA Science Inventory

    The rapid emergence of rotating biological contactor (RBC) technology as an alternative secondary wastewater treatment process has increased the need to review their performance history to provide information to the design engineer. This study, to review and compare current desig...

  17. 14 CFR 435.43 - Payload reentry review requirements and procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING REENTRY OF A REENTRY VEHICLE OTHER THAN A REUSABLE LAUNCH VEHICLE (RLV) Payload Reentry Review and Determination § 435.43 Payload reentry review requirements and... shall apply to the payload reentry review conducted for a license to reenter a reentry vehicle...

  18. 14 CFR 435.43 - Payload reentry review requirements and procedures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING REENTRY OF A REENTRY VEHICLE OTHER THAN A REUSABLE LAUNCH VEHICLE (RLV) Payload Reentry Review and Determination § 435.43 Payload reentry review requirements and... shall apply to the payload reentry review conducted for a license to reenter a reentry vehicle...

  19. 14 CFR 435.43 - Payload reentry review requirements and procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING REENTRY OF A REENTRY VEHICLE OTHER THAN A REUSABLE LAUNCH VEHICLE (RLV) Payload Reentry Review and Determination § 435.43 Payload reentry review requirements and... shall apply to the payload reentry review conducted for a license to reenter a reentry vehicle...

  20. 14 CFR 435.43 - Payload reentry review requirements and procedures.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING REENTRY OF A REENTRY VEHICLE OTHER THAN A REUSABLE LAUNCH VEHICLE (RLV) Payload Reentry Review and Determination § 435.43 Payload reentry review requirements and... shall apply to the payload reentry review conducted for a license to reenter a reentry vehicle...

  1. TOPICAL REVIEW: Tritium inventory in ITER plasma-facing materials and tritium removal procedures

    NASA Astrophysics Data System (ADS)

    Roth, Joachim; Tsitrone, Emmanuelle; Loarer, Thierry; Philipps, Volker; Brezinsek, Sebastijan; Loarte, Alberto; Counsell, Glenn F.; Doerner, Russell P.; Schmid, Klaus; Ogorodnikova, Olga V.; Causey, Rion A.

    2008-10-01

    Interactions between the plasma and the vessel walls constitute a major engineering problem for next step fusion devices, such as ITER, determining the choice of the plasma-facing materials. A prominent issue in this choice is the tritium inventory build-up in the vessel, which must be limited for safety reasons. The initial material selection, i.e. beryllium (Be) on the main vessel walls, tungsten (W) on the divertor upper baffle and dome, and carbon fibre composite around the strike points on the divertor plates, results both from the attempt to reduce the tritium inventory and to optimize the lifetime of the plasma-facing components. In the framework of the EU Task Force on Plasma-Wall Interaction (PWI TF), the many physics aspects governing the tritium inventory are brought together. Together with supporting information from international experts represented by the ITPA SOL/DIV section, this paper describes the present status of knowledge of the in-vessel tritium inventory build-up. Firstly, the main results from present fusion devices in this field are briefly reviewed. Then, the processes involved are discussed: implantation, trapping and diffusion in plasma-facing materials are considered as well as surface erosion and co-deposition of tritium with eroded material. The intermixing of the different materials and its influence on hydrogen retention and co-deposition is a major source of uncertainty on present estimates and is also addressed. Based on the previous considerations, estimates for the tritium inventory build-up are given for the initial choice of ITER materials, as well as for alternative options. Present estimates indicate a build-up of the tritium inventory to the administrative limit within a few hundred nominal full power D : T discharges, co-deposition with carbon being the dominant process. Therefore, tritium removal methods are also an active area of research within the EU PWI TF, and are discussed. An integrated operational scheme to slow

  2. Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Pancreatic Lesions: A Systematic Review of Technical and Procedural Variables

    PubMed Central

    Jani, Bhairvi S.; Rzouq, Fadi; Saligram, Shreyas; Lim, Diego; Rastogi, Amit; Bonino, John; Olyaee, Mojtaba

    2016-01-01

    Endoscopic ultrasound (EUS)-guided tissue acquisition has emerged over the last decade as an invaluable diagnostic tool in approaching the different pancreatic lesions. Given the safety and minimal invasiveness of this approach combined with the high diagnostic yield, it became the standard of care when dealing with different pancreatic pathologies. However, some variables regarding this procedure remain not fully understood. These can influence the diagnostic yield of the procedure and include the presence of the on-site cytopathologist, the type and size of the needle used as well as obtaining aspiration versus core biopsy, the number of passes and the sampling technique, and the role of suction and stylet use among others. We performed a comprehensive literature search using PubMed, Google Scholar, and Embase for studies that assessed these variables. Eligible studies were analyzed using several parameters such as technique and procedure, with the aim of reviewing results from an evidence-based standpoint. PMID:27011940

  3. The efficacy of hypnosis in the reduction of procedural pain and distress in pediatric oncology: a systematic review.

    PubMed

    Wild, Matt R; Espie, Colin A

    2004-06-01

    Children who suffer from cancer have to endure regular, painful medical procedures that are associated with a considerable degree of psychosocial distress. Hypnosis has been successfully employed in the management of pain and distress in the adult population, but is not well studied in pediatric populations. This review systematically evaluates the systematic research conducted in the field of procedure-related pain management in pediatric oncology within the context of a nationally agreed framework for the assessment of research evidence. It is concluded that there is not currently enough robust research evidence to recommend that hypnosis should form part of best practice guidelines for the management of procedure-related pain in pediatric oncology. However, there is sufficient evidence to justify larger-scale, appropriately controlled studies. A number of recommendations are made regarding future research. PMID:15194906

  4. Distal Clavicle Osteolysis after Modified Weaver-Dunn's Procedure for Chronic Acromioclavicular Dislocation: A Case Report and Review of Complications

    PubMed Central

    Santana, Fernando; Mingo, Felipe; Piñol, Ignasi; Solano, Albert; Puig-Verdié, Lluís; Torrens, Carles

    2014-01-01

    Distal clavicle osteolysis after acromioclavicular joint stabilization has only been described after the use of hardware for clavicle stabilization or synthetic graft causing a foreign body reaction. This paper reports a very rare case of distal clavicle osteolysis after modified Weaver-Dunn procedure for the treatment of chronic acromioclavicular joint dislocation. The paper also provides a comprehensive review of complications of this surgical technique and discusses a potential vascular etiology and preventive strategies aimed at avoiding clavicle osteolysis. PMID:25544923

  5. Complication Rates and Patency of Radiologically Guided Mushroom Gastrostomy, Balloon Gastrostomy, and Gastrojejunostomy: A Review of 250 Procedures

    SciTech Connect

    Yip, Doris; Vanasco, Matthew; Funaki, Brian

    2004-01-15

    To compare complication rates and tube performance of percutaneous mushroom gastrostomy, balloon gastrostomy, and gastrojejunostomy. Between September 9, 1999 and April 23, 2001, 203 patients underwent 250 radiologically guided percutaneous gastrostomy and gastrojejunostomy procedures. Follow-up was conducted through chart reviews and review of our interventional radiology database. Procedural and catheter-related complications were recorded. Chi-square statistical analysis was performed. In patients receiving mushroom-retained gastrostomy catheters (n = 114), the major complication rate was 0.88% (n = 1), the minor complication rate was 5.3% (n = 6), and the tube complication rate was 4.4% (n = 5). In patients receiving balloon-retained gastrostomy tubes (n = 67), the major complication rate was 0, the minor complication rate was 4.5% (n = 3), and the tube complication rate was 34.3% (n = 23). In patients receiving gastrojejunostomy catheters (n = 69), the major complication rate was 1.4% (n = 1), the minor complication rate was 2.9% (n = 2), and the tube complication rate was 34.8% (n = 24). No statistically significant differences were found between procedural or peri-procedural complications among the different types of tubes. Mushroom-retained catheters had significantly fewer tube complications (p < 0.01). Percutaneous gastrostomy and gastrojejunostomy have similar procedural and peri-procedural complication rates. Mushroom gastrostomy catheters have fewer tube-related complications compared with balloon gastrostomy and gastrojejunostomy catheters. In addition, mushroom-retained catheters exhibit the best overall long-term tube patency and are therefore the gastrostomy catheter of choice.

  6. A Systematic Review of Systematic Reviews and Panoramic Meta-Analysis: Staples versus Sutures for Surgical Procedures

    PubMed Central

    Hemming, Karla; Pinkney, Thomas; Futaba, Kay; Pennant, Mary; Morton, Dion G.; Lilford, Richard J.

    2013-01-01

    Objective To systematically evaluate the evidence across surgical specialties as to whether staples or sutures better improve patient and provider level outcomes. Design A systematic review of systematic reviews and panoramic meta-analysis of pooled estimates. Results Eleven systematic reviews, including 13,661 observations, met the inclusion criteria. In orthopaedic surgery sutures were found to be preferable, and for appendicial stump sutures were protective against both surgical site infection and post surgical complications. However, staples were protective against leak in ilecolic anastomosis. For all other surgery types the evidence was inconclusive with wider confidence intervals including the possibly of preferential outcomes for surgical site infection or post surgical complication for either staples or sutures. Whilst reviews showed substantial variation in mean differences in operating time (I2 94%) there was clear evidence of a reduction in average operating time across all surgery types. Few reviews reported on length of stay, but the three reviews that did (I2 0%, including 950 observations) showed a non significant reduction in length of stay, but showed evidence of publication bias (P-value for Egger test 0.05). Conclusions Evidence across surgical specialties indicates that wound closure with staples reduces the mean operating time. Despite including several thousand observations, no clear evidence of superiority emerged for either staples or sutures with respect to surgical site infection, post surgical complications, or length of stay. PMID:24116028

  7. Fluorescence, PRI and canopy temperature for water stress detection in cereal crops

    NASA Astrophysics Data System (ADS)

    Panigada, C.; Rossini, M.; Meroni, M.; Cilia, C.; Busetto, L.; Amaducci, S.; Boschetti, M.; Cogliati, S.; Picchi, V.; Pinto, F.; Marchesi, A.; Colombo, R.

    2014-08-01

    Narrow-band multispectral remote sensing techniques and thermal imagery were investigated for water stress detection in cereal crops. Visible and near infrared AISA Eagle (Specim, Finland) and thermal AHS-160 (Sensytech Inc., USA) imageries were acquired with an airborne survey on a farm-level experimental site where maize (Zea mays L.) and sorghum (Sorghum bicolor L.) were grown with three different irrigation treatments. Vegetation biophysical and eco-physiological measurements were collected concurrently with the airborne campaign. Leaf fluorescence yield (ΔF/Fm‧) resulted to be a good indirect measure of water stress. Therefore, ΔF/Fm‧ measurements were compared against remotely sensed indicators: (i) the Photochemical Reflectance Index (PRI), (ii) the sun-induced chlorophyll fluorescence at 760 nm (F760), retrieved by the Fraunhofer line depth method and (iii) the canopy temperature (TC) calculated decoupling soil and vegetation contributions. TC was related to ΔF/Fm‧ with the highest determination coefficient (R2 = 0.65), followed by PRI586 (reference band at 586 nm) (R2 = 0.51). The relationship with F760 was significant but weaker (R2 = 0.36). The coefficient of determination increased up to 0.54 when pigment concentration was considered by multiplying ΔF/Fm‧ and chlorophyll content, confirming the close relationship between passive fluorescence signal, pigment content and light photosystem efficiency. PRI586, F760 and TC maps were produced in maize and sorghum plots. The differences in the average values of PRI586, F760 and TC extracted from the plots with different water treatments showed that water treatments were well discriminated in maize plots by the three remotely sensed indicators. This was confirmed by the visual observation of the PRI586, F760 and TC maps, while in sorghum plots, F760 and TC appeared more sensitive to water stress compared to PRI586.

  8. Review of Measurement Instruments and Procedures for Assessing Visual Behaviors: Implications for Quantitative Measurement.

    ERIC Educational Resources Information Center

    Janssen, Cynthia M.

    The assessment of vision as it relates to and interacts with motor development is reviewed. The focus is on eye readiness skills normally occuring in infants' first few months of life and preceding eye-hand coordination. These visual skills fall into three categories: fixation, tracking, and scanning. Six standardized scales are reviewed and…

  9. Procedures for the ethical review of public health surveillance protocols. Commentary.

    PubMed

    Petrini, Carlo

    2014-01-01

    The present commentary is based on the following considerations: 1) for the purposes of authorisation, a distinction is drawn between "research" and "intervention". The procedures for authorising the former are more complex, the relevant controls are stricter and approval has to be granted by a Research Ethics Committee (REC); 2) although the debate is still open, it is barely credible to claim that public health surveillance is not a form of research. It should, therefore, be subject to rigorous ethical assessment; 3) when addressing specifically the issue of surveillance, it would be appropriate to shift the focus of attention from the type of procedure (research/intervention) to the risk implied in that procedure; 4) much emphasis has hitherto been placed on the risks that public health surveillance may imply for the protection of personal data; 5) the emphasis on the protection of personal data is frequently excessive and the risks should be examined in a broader context. PMID:24695246

  10. Angulated Implants: An Alternative to Bone Augmentation and Sinus Lift Procedure: Systematic Review

    PubMed Central

    Bulbule, Nilesh; Kakade, Dilip; Shah, Riddhi

    2015-01-01

    Rehabilitation of completely edentulous patients with implant becomes challenging due to reduced amount of bone available and pneumatisation of maxillary sinus or both. To successfully treat such patients, prior to implant placement, patient has to undergo invasive procedures like sinus lift and/or bone augmentation which is not possible many time due to many reasons. This article focuses on an alternative treatment procedure in which two posterior implants are placed at an angle and two anterior implants are placed axially thereby eliminating the need for sinus lift or bone augmentation procedures. This article broadly discusses this “All on Four” concept in all aspects, its effects on bone, prosthesis survival, forces acting etc along with various related studies. PMID:25954718

  11. Evaluation of DSS-14 pedestal-review of top surface repair procedures

    NASA Technical Reports Server (NTRS)

    Oesterle, R. G.; Musser, D. W.; Salse, E. A. B.

    1983-01-01

    Proposed repair procedures for the top surface of the pedestal supporting the hydrostatic bearing runner for the 64m Antenna are presented. These procedures included: (1) removal of existing grout and concrete to approximately 8 in. below original concrete surface using a presplitting technique with expansive cement followed by secondary breaking; (2) preparation of exposed concrete surface including an epoxy bonding agent; and (3) replacement of material removed with 8 in. of new concrete surface including an epoxy bonding agent; and (4) replacement of material removed with 8 in. of new concrete and 4 in. of new grout.

  12. Wine Processing: A Critical Review of Physical, Chemical, and Sensory Implications of Innovative Vinification Procedures.

    PubMed

    Baiano, Antonietta; Scrocco, Carmela; Sepielli, Grazia; Del Nobile, Matteo Alessandro

    2016-10-25

    Wine is one of the most popular alcoholic beverages in the world, although it is mainly consumed in European and South American countries. Several thousand years have passed since the product of grape fermentation was accidentally discovered. Over the last 100-150 years, winemaking has been completely revolutionized in terms of procedures and equipment. This work is aimed to give a comprehensive overview of the consolidated use of winemaking innovations that are still in the development stage or already applied to commercial products. Their effects on physical, chemical, and sensory characteristics of wines will also be discussed in comparison with the consolidated vinification procedures. PMID:25629416

  13. Evaluation of DSS-14 pedestal-review of top surface repair procedures

    NASA Astrophysics Data System (ADS)

    Oesterle, R. G.; Musser, D. W.; Salse, E. A. B.

    1983-05-01

    Proposed repair procedures for the top surface of the pedestal supporting the hydrostatic bearing runner for the 64m Antenna are presented. These procedures included: (1) removal of existing grout and concrete to approximately 8 in. below original concrete surface using a presplitting technique with expansive cement followed by secondary breaking; (2) preparation of exposed concrete surface including an epoxy bonding agent; and (3) replacement of material removed with 8 in. of new concrete surface including an epoxy bonding agent; and (4) replacement of material removed with 8 in. of new concrete and 4 in. of new grout.

  14. Long-Term Memory: A Review and Meta-Analysis of Studies of Declarative and Procedural Memory in Specific Language Impairment

    ERIC Educational Resources Information Center

    Lum, Jarrad A. G.; Conti-Ramsden, Gina

    2013-01-01

    This review examined the status of long-term memory systems in specific language impairment (SLI)--declarative memory and aspects of procedural memory in particular. Studies included in the review were identified following a systematic search of the literature and findings combined using meta-analysis. This review showed that individuals with SLI…

  15. 76 FR 26302 - Submission for OMB Review; Comment Request; Reunification Procedures for Unaccompanied Alien...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-06

    ...; Reunification Procedures for Unaccompanied Alien Children Description Following the passage of the 2002 Homeland... Resettlement (ORR), is charged with the care and placement of unaccompanied alien children in Federal custody... unaccompanied alien. Annual Burden Estimates Number of Average Instrument Number of responses per burden...

  16. Information Exchange Procedures Manual (Field Review Edition): A Synopsis. Technical Report No. 46.

    ERIC Educational Resources Information Center

    Romney, Leonard C.

    The purpose of the Information Exchange Procedures (IEP) projects is to create among higher education institutions the capability for exchanging and reporting that information, both financial and otherwise, necessary to calculate and evaluate costs (1) by discipline and course level and (2) by student program and student level. Most uses of…

  17. Corralling Your Camp Horse Program: Reviewing Your Policies and Procedures and Creating a Written Manual.

    ERIC Educational Resources Information Center

    Glunt, Jim

    2000-01-01

    Camps offering horse programs need to have written policies and procedures to ensure quality control and risk minimization. Basic elements of a horse program manual include routine care of horses; general guidelines relating to participants, program, and staff; and emergency plans. Four information resources are presented. (TD)

  18. Community College Grievance Procedures: A Review of Contract Content in Ninety-Four Colleges

    ERIC Educational Resources Information Center

    Mannix, Thomas

    1974-01-01

    After examining grievance procedures of community colleges, the author compares the range of differences on specific aspects of the contractual arrangement for 94 community colleges as to the type of arbitration, type of grievance, time limit, agent, expiration, grievance definition, and limitation of arbitration. (Editor/PG)

  19. A literature review of record linkage procedures focusing on infant health outcomes.

    PubMed

    Machado, Carla Jorge

    2004-01-01

    Record linkage is a powerful tool in assembling information from different data sources and has been used by a number of public health researchers. In this review, we provide an overview of the record linkage methodologies, focusing particularly on probabilistic record linkage. We then stress the purposes and research applications of linking records by focusing on studies of infant health outcomes based on large data sets, and provide a critical review of the studies in Brazil. PMID:15073615

  20. Distinct localization of Collagen Q and PRiMA forms of Acetylcholinesterase at the neuromuscular junction

    PubMed Central

    Bernard, Véronique; Girard, Emmanuelle; Hrabovska, Anna; Camp, Shelley; Taylor, Palmer; Plaud, Benoit; Krejci, Eric

    2015-01-01

    Acetylcholinesterase (AChE) terminates the action of acetylcholine at cholinergic synapses thereby preventing rebinding of acetylcholine to nicotinic post-synaptic receptors at the neuromuscular junction. Here we show that AChE is not localized close to these receptors on the post-synaptic surface, but is instead clustered along the presynaptic membrane and deep in the post-synaptic folds. Because AChE is anchored by ColQ in the basal lamina and is linked to the plasma membrane by a transmembrane subunit (PRiMA), we used a genetic approach to evaluate the respective contribution of each anchoring oligomer. By visualization and quantification of AChE in mouse strains devoid of ColQ, PRiMA or AChE, specifically in the muscle, we found that along the nerve terminus, the vast majority of AChE is anchored by ColQ that is only produced by the muscle, whereas very minor amounts of AChE are anchored by PRiMA that is produced by motoneurons. In its synaptic location, AChE is therefore positioned to scavenge ACh that effluxes from the nerve by non-quantal release. AChE-PRiMA, produced by the muscle, is diffusely distributed along the muscle in extra-junctional regions. PMID:20883790

  1. Diurnal and directional responses of chlorophyll fluorescence and pri in a cornfield

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Two high spectral resolution reflectance-based indices were used to assess whether vegetation in a cornfield was performing near-optimally or exhibiting symptoms of environmental stress. These were the Photochemical Reflectance Index (PRI) and solar-induced Chlorophyll Fluorescence (SIF). This study...

  2. Incidence of adverse events in paediatric procedural sedation in the emergency department: a systematic review and meta-analysis

    PubMed Central

    Bellolio, M Fernanda; Puls, Henrique A; Anderson, Jana L; Gilani, Waqas I; Murad, M Hassan; Barrionuevo, Patricia; Erwin, Patricia J; Wang, Zhen; Hess, Erik P

    2016-01-01

    Objective and design We conducted a systematic review and meta-analysis to evaluate the incidence of adverse events in the emergency department (ED) during procedural sedation in the paediatric population. Randomised controlled trials and observational studies from the past 10 years were included. We adhere to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Setting ED. Participants Children. Interventions Procedural sedation. Outcomes Adverse events like vomiting, agitation, hypoxia and apnoea. Meta-analysis was performed with random-effects model and reported as incidence rates with 95% CIs. Results A total of 1177 studies were retrieved for screening and 258 were selected for full-text review. 41 studies reporting on 13 883 procedural sedations in 13 876 children (≤18 years) were included. The most common adverse events (all reported per 1000 sedations) were: vomiting 55.5 (CI 45.2 to 65.8), agitation 17.9 (CI 12.2 to 23.7), hypoxia 14.8 (CI 10.2 to 19.3) and apnoea 7.1 (CI 3.2 to 11.0). The need to intervene with either bag valve mask, oral airway or positive pressure ventilation occurred in 5.0 per 1000 sedations (CI 2.3 to 7.6). The incidences of severe respiratory events were: 34 cases of laryngospasm among 8687 sedations (2.9 per 1000 sedations, CI 1.1 to 4.7; absolute rate 3.9 per 1000 sedations), 4 intubations among 9136 sedations and 0 cases of aspiration among 3326 sedations. 33 of the 34 cases of laryngospasm occurred in patients who received ketamine. Conclusions Serious adverse respiratory events are very rare in paediatric procedural sedation in the ED. Emesis and agitation are the most frequent adverse events. Hypoxia, a late indicator of respiratory depression, occurs in 1.5% of sedations. Laryngospasm, though rare, happens most frequently with ketamine. The results of this study provide quantitative risk estimates to facilitate shared decision-making, risk communication, informed consent and

  3. Retrospective Review of Propofol Dosing for Procedural Sedation in Pediatric Patients

    PubMed Central

    Milius, Eryn M.; Papademetrious, Tricia R.; Heitlinger, Leo A.

    2012-01-01

    OBJECTIVES The purpose of this study was to determine the total propofol dose (mg/kg) for non-emergent pediatric procedural sedation and evaluate dosing differences with regard to a patient's sex, age, and body mass index. Adverse events were recorded and evaluated to determine whether certain patient groups were at a higher risk than others. METHODS This study was a retrospective observational pilot study including patients 0 to 18 years of age admitted between January 2008 and November 2009 for non-emergent gastrointestinal endoscopic procedures or radiologic imaging, who received propofol for procedural sedation. Data gathered included sex, age, height, weight, chronic medical conditions and medication use, concomitant anesthetic gas, preprocedure midazolam, procedure length, propofol dose in mg/kg, other medications administered during procedure, and adverse events that occurred. Comparisons between adverse event groups and categories of baseline characteristics were made using the Wilcoxon signed-rank, Kruskal-Wallis nonparametric and Pearson's chisquare tests, as appropriate. RESULTS A total of 101 patients met inclusion criteria and were included in the analysis. The mean dose of propofol required for female patients was 3.7 mg/kg versus 3.4 mg/kg for males (p=0.3). The mean dose of propofol for patients ≤9 years, 10 to 12 years, and >12 years was 3.2, 3.9, and 3.9 mg/kg, respectively (p=0.25). The mean dose of propofol for underweight, healthy weight, overweight, and obese patients was 4.2, 3.9, 3.6, and 2.6 mg/kg, respectively (p=0.38). Hypotension occurred in 42.6% of patients, and bradycardia occurred in 13.9% of patients. CONCLUSIONS There were no differences in dose requirements based on sex or age. The difference in dosing between different body weight categories was not statistically significant. The dose of propofol was higher in patients that experienced bradycardia and hypotension, but there was no statistical significance. Given the above

  4. Response to the independent technical review of the UMTRA Project procedures and practices for well drilling and development

    SciTech Connect

    Not Available

    1994-07-01

    This report is a response to the findings and recommendations contained in the ITR report. The text of this document summarizes each ITR finding and recommendation, presents the TAC response, and concludes that implementation of many of the recommendations would benefit the UMTRA Project. Implementation of the recommendations represents ongoing improvement to the TAC well installation and development procedures and will result, in lower overall project costs. Appendix B is an implementation plan that groups similar or complementary action items, provides a schedule for implementation, identifies the group or people responsible for the changes, and estimates hours to implement the changes. The four major action items are as follows: (1) ITR Reevaluation, (2) Well Installation SOP Review and Revision, (3) Well Installation Contract Review and Revision, and (4) TAC and DOE Communications Improvement. The hours listed to implement the improvements are intended to be estimates for budgeting and planning purposes for the remainder of this fiscal year and the upcoming fiscal year.

  5. Removal of Review and Reclassification Procedures for Biological Products Licensed Prior to July 1, 1972. Final rule.

    PubMed

    2016-02-12

    The Food and Drug Administration (FDA, the Agency, or we) is removing two regulations that prescribe procedures for FDA's review and classification of biological products licensed before July 1, 1972. FDA is taking this action because the two regulations are obsolete and no longer necessary in light of other statutory and regulatory authorities established since 1972, which allow FDA to evaluate and monitor the safety and effectiveness of all biological products. In addition, other statutory and regulatory authorities authorize FDA to revoke a license for biological products because they are not safe and effective, or are misbranded. FDA is taking this action as part of its retrospective review of its regulations to promote improvement and innovation. PMID:26878738

  6. 40 CFR 132.5 - Procedures for adoption and EPA review.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Attorney General or other appropriate legal authority pursuant to 40 CFR 123.62 and 40 CFR 131.6(e) as... System (NPDES) program modifications under 40 CFR 123.62; and (4) General information which will aid EPA... modifications. The public notice shall conform with the requirements of 40 CFR 123.62. (f) After review of...

  7. 40 CFR 132.5 - Procedures for adoption and EPA review.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Attorney General or other appropriate legal authority pursuant to 40 CFR 123.62 and 40 CFR 131.6(e) as... System (NPDES) program modifications under 40 CFR 123.62; and (4) General information which will aid EPA... modifications. The public notice shall conform with the requirements of 40 CFR 123.62. (f) After review of...

  8. 40 CFR 132.5 - Procedures for adoption and EPA review.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Attorney General or other appropriate legal authority pursuant to 40 CFR 123.62 and 40 CFR 131.6(e) as... System (NPDES) program modifications under 40 CFR 123.62; and (4) General information which will aid EPA... modifications. The public notice shall conform with the requirements of 40 CFR 123.62. (f) After review of...

  9. 40 CFR 132.5 - Procedures for adoption and EPA review.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Attorney General or other appropriate legal authority pursuant to 40 CFR 123.62 and 40 CFR 131.6(e) as... System (NPDES) program modifications under 40 CFR 123.62; and (4) General information which will aid EPA... modifications. The public notice shall conform with the requirements of 40 CFR 123.62. (f) After review of...

  10. 40 CFR 132.5 - Procedures for adoption and EPA review.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Attorney General or other appropriate legal authority pursuant to 40 CFR 123.62 and 40 CFR 131.6(e) as... System (NPDES) program modifications under 40 CFR 123.62; and (4) General information which will aid EPA... modifications. The public notice shall conform with the requirements of 40 CFR 123.62. (f) After review of...

  11. 24 CFR 55.10 - Environmental review procedures under 24 CFR parts 50 and 58.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... under 24 CFR parts 50 and 58. 55.10 Section 55.10 Housing and Urban Development Office of the Secretary... under 24 CFR parts 50 and 58. (a) Where an environmental review is required under the National Environmental Policy Act of 1969 (NEPA) (42 U.S.C. 4321 et seq.), and 24 CFR part 50 or part 58, compliance...

  12. 34 CFR 602.33 - Procedures for review of agencies during the period of recognition.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... recognition. 602.33 Section 602.33 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION THE SECRETARY'S RECOGNITION OF ACCREDITING AGENCIES The Recognition Process Application and Review by Department Staff § 602.33...

  13. 34 CFR 602.33 - Procedures for review of agencies during the period of recognition.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... recognition. 602.33 Section 602.33 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION THE SECRETARY'S RECOGNITION OF ACCREDITING AGENCIES The Recognition Process Application and Review by Department Staff § 602.33...

  14. 34 CFR 602.33 - Procedures for review of agencies during the period of recognition.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... recognition. 602.33 Section 602.33 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION THE SECRETARY'S RECOGNITION OF ACCREDITING AGENCIES The Recognition Process Application and Review by Department Staff § 602.33...

  15. 34 CFR 602.33 - Procedures for review of agencies during the period of recognition.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... recognition. 602.33 Section 602.33 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION THE SECRETARY'S RECOGNITION OF ACCREDITING AGENCIES The Recognition Process Application and Review by Department Staff § 602.33...

  16. 34 CFR 602.33 - Procedures for review of agencies during the period of recognition.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... recognition. 602.33 Section 602.33 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION THE SECRETARY'S RECOGNITION OF ACCREDITING AGENCIES The Recognition Process Application and Review by Department Staff § 602.33...

  17. 49 CFR 194.121 - Response plan review and update procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... SAFETY RESPONSE PLANS FOR ONSHORE OIL PIPELINES Response Plans § 194.121 Response plan review and update... discharge volume; (3) The type of oil transported, if the type affects the required response resources, such as a change from crude oil to gasoline; (4) The name of the oil spill removal organization;...

  18. 49 CFR 194.121 - Response plan review and update procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SAFETY RESPONSE PLANS FOR ONSHORE OIL PIPELINES Response Plans § 194.121 Response plan review and update... discharge volume; (3) The type of oil transported, if the type affects the required response resources, such as a change from crude oil to gasoline; (4) The name of the oil spill removal organization;...

  19. A Review of Research on Procedures for Teaching Safety Skills to Persons with Developmental Disabilities

    ERIC Educational Resources Information Center

    Dixon, Dennis R.; Bergstrom, Ryan; Smith, Marlena N.; Tarbox, Jonathan

    2010-01-01

    Safety skills are an important but often neglected area of training for persons with developmental disabilities (DD). The present study reviewed the literature on teaching safety skills to persons with DD. Safety skills involve a variety of behaviors such as knowing how to cross the street or what to do in case of a house fire. A number of studies…

  20. 40 CFR 63.54 - Preconstruction review procedures for new affected sources.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... advertisement in the area affected of the location of the source information and analysis specified in § 63.52(f... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE... source subject to § 63.52(c)(1). The purpose of this section is to describe alternative review...

  1. 15 CFR 923.133 - Procedure for conducting continuing reviews of approved State CZM programs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... approved CZM program; (B) The management agency is effectively playing a leadership role in coastal issues..., DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS... performance of coastal States with respect to coastal management. Each review shall include a...

  2. 15 CFR 923.133 - Procedure for conducting continuing reviews of approved State CZM programs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... approved CZM program; (B) The management agency is effectively playing a leadership role in coastal issues..., DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS... performance of coastal States with respect to coastal management. Each review shall include a...

  3. 15 CFR 923.133 - Procedure for conducting continuing reviews of approved State CZM programs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... approved CZM program; (B) The management agency is effectively playing a leadership role in coastal issues..., DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS... performance of coastal States with respect to coastal management. Each review shall include a...

  4. 15 CFR 923.133 - Procedure for conducting continuing reviews of approved State CZM programs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... approved CZM program; (B) The management agency is effectively playing a leadership role in coastal issues..., DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS... performance of coastal States with respect to coastal management. Each review shall include a...

  5. 15 CFR 923.133 - Procedure for conducting continuing reviews of approved State CZM programs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... approved CZM program; (B) The management agency is effectively playing a leadership role in coastal issues..., DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS... performance of coastal States with respect to coastal management. Each review shall include a...

  6. 15 CFR 923.127 - Formal application for financial assistance and application review and approval procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... CFR part 923. (b) Applications for financial assistance under this part must be in a separate section... of 15 CFR part 923. (d) States will be notified of their section 309 awards at the time they are... pursuant to § 923.126(c)(2), anonymous copies of the project reviews provided to the...

  7. A review of 105 consecutive uniport endoscopic plantar fascial release procedures for the treatment of chronic plantar fasciitis.

    PubMed

    Morton, Troy N; Zimmerman, Jeffrey P; Lee, Michael; Schaber, John D

    2013-01-01

    Plantar fasciitis is a common cause of heel pain in the U.S. Army soldier, resulting in a significant loss of man hours. Given the heavy operations tempo of the U.S. military, successful treatment options need to be considered and used as quickly as possible. Plantar fasciitis can be successfully treated in up to 90% of patients using conservative measures. Operative intervention might need to be considered for those in whom conservative measures have failed. The present report is a review of 105 consecutive uniport endoscopic plantar fascial release procedures performed by the principal investigator during a 9-year period. The following data were collected and analyzed: gender, age, weight, height, body mass index, medical treatment facility, procedure laterality, preoperative pain levels, postoperative pain levels at 3 months, first ambulatory day in the controlled ankle motion boot, return to activity as tolerated, and complications. Three major points were of interest: evidence of improvement in chronic plantar fasciitis when treated with uniport endoscopic procedures; the patient attributes associated with self-reported pain levels 90 days postoperatively; and the patient attributes associated with the average time until patients were able to return to activities as tolerated in a controlled ankle motion boot. It was noted that 44.5% of those with a body mass index of 29.80 kg/m(2) or greater reported a postoperative pain level of 0; and 96.3% of those with a body mass index of 25.53 kg/m(2) or less reported postoperative pain levels of 0. The analyzed data were used to characterize the clinical outcomes of the procedure, identify changes in outcome with surgeon experience, and identify whether certain patient subgroups have better outcomes, allowing surgeons to identify which patient might be the best candidates for an endoscopic release procedure. PMID:23177328

  8. Perianesthetic Mortality in Domestic Animals: A Retrospective Study of Postmortem Lesions and Review of Autopsy Procedures.

    PubMed

    DeLay, J

    2016-09-01

    Autopsy of animals that die in the perianesthetic period allows identification of anesthetic and surgical complications as well as preexisting disease conditions that may have contributed to mortality. In most studies to date investigating perianesthetic mortality in animals, inclusion of autopsy data is very limited. This retrospective study evaluated autopsy findings in 221 cases of perianesthetic death submitted to a veterinary diagnostic laboratory from primary care and referral hospitals. Canine (n = 105; 48%) and feline (n = 90; 41%) cases predominated in the study, involving elective (71%) and emergency (19%) procedures. The clinical history provided to the pathologist was considered incomplete in 42 of 221 cases (19%), but this history was considered essential for evaluating the circumstances of perianesthetic death. Disease had been recognized clinically in 69 of 221 animals (31%). Death occurred in the premedication or sedation (n = 19; 9%), induction (n = 22; 11%), or maintenance (n = 73; 35%) phases or in the 24 hours postanesthesia (n = 93 animals; 45%). Lesions indicative of significant natural disease were present in 130 of 221 animals (59%), mainly involving the heart, upper respiratory tract, or lungs. Surgical or anesthesia-associated complications were identified in 10 of 221 cases (5%). No lesions were evident in 80 of 221 animals (36%), the majority of which were young, healthy, and undergoing elective surgical procedures. Lesions resulting from cardiopulmonary resuscitation were identified in 75 of 221 animals (34%). Investigation of perianesthetic death cases should be done with knowledge of prior clinical findings and antemortem surgical and medical procedures; the autopsy should particularly focus on the cardiovascular and respiratory system, including techniques to identify pneumothorax and venous air embolism. PMID:27371539

  9. Distraction techniques for children undergoing procedures: a critical review of pediatric research.

    PubMed

    Koller, Donna; Goldman, Ran D

    2012-12-01

    Pediatric patients are often subjected to procedures that can cause pain and anxiety. Although pharmacologic interventions can be used, distraction is a simple and effective technique that directs children's attention away from noxious stimuli. However, there is a multitude of techniques and technologies associated with distraction. Given the range of distraction techniques, the purpose of this article was to provide a critical assessment of the evidence-based literature that can inform clinical practice and future research. Recommendations include greater attention to child preferences and temperament as a means of optimizing outcomes and heightening awareness around child participation in health care decision making. PMID:21925588

  10. STS-55 SL-D2 crew reviews preflight CEIT procedures in KSC conference room

    NASA Technical Reports Server (NTRS)

    1993-01-01

    STS-55 Spacelab Deutsche 2 (SL-D2) crewmembers, seated at a conference table, discuss Crew Equipment Interface Test (CEIT) procedures in a briefing room at the Kennedy Space Center (KSC). From left are Mission Specialist 1 (MS1) and Payload Commander (PLC) Jerry L. Ross, German Payload Specialist 1 Ulrich Walter, Pilot Terence T. Henricks, Commander Steven R. Nagel, MS3 Bernard J. Harris, Jr, German Payload Specialist 2 Hans Schlegel, and MS2 Charles J. Precourt. Seated in the foreground are KSC technicians and payload integration officers. Walter and Schlegel are representatives from DLR. View provided by KSC with alternate KSC number KSC-93PC-212.

  11. Dimeric structure of the N-terminal domain of PriB protein from Thermoanaerobacter tengcongensis solved ab initio

    SciTech Connect

    Liebschner, Dorothee; Brzezinski, Krzysztof; Dauter, Miroslawa; Dauter, Zbigniew; Nowak, Marta; Kur, Józef; Olszewski, Marcin

    2012-12-01

    The N-terminal domain of the PriB protein from the thermophilic bacterium T. tengcongensis (TtePriB) was expressed and its crystal structure has been solved at the atomic resolution of 1.09 Å by direct methods. PriB is one of the components of the bacterial primosome, which catalyzes the reactivation of stalled replication forks at sites of DNA damage. The N-terminal domain of the PriB protein from the thermophilic bacterium Thermoanaerobacter tengcongensis (TtePriB) was expressed and its crystal structure was solved at the atomic resolution of 1.09 Å by direct methods. The protein chain, which encompasses the first 104 residues of the full 220-residue protein, adopts the characteristic oligonucleotide/oligosaccharide-binding (OB) structure consisting of a five-stranded β-barrel filled with hydrophobic residues and equipped with four loops extending from the barrel. In the crystal two protomers dimerize, forming a six-stranded antiparallel β-sheet. The structure of the N-terminal OB domain of T. tengcongensis shows significant differences compared with mesophile PriBs. While in all other known structures of PriB a dimer is formed by two identical OB domains in separate chains, TtePriB contains two consecutive OB domains in one chain. However, sequence comparison of both the N-terminal and the C-terminal domains of TtePriB suggests that they have analogous structures and that the natural protein possesses a structure similar to a dimer of two N-terminal domains.

  12. Are there specific indications for the different alveolar bone augmentation procedures for implant placement? A systematic review.

    PubMed

    Milinkovic, I; Cordaro, L

    2014-05-01

    Bone resorption following tooth loss often interferes with dental implant placement in a desired position, and requires additional bone augmentation procedures. Many techniques have been described to augment and reconstruct alveolar ridge width and height. The aim of this study was to systemically review whether there is evidence to provide indications for the various bone augmentation procedures based on defect dimension and type. An electronic search of the Medline database and Cochrane library, complemented by a manual search, was performed. Inclusion criteria for partial edentulism were: clinical trials on bone augmentation procedures in preparation or at the time of implant placement, reporting preoperative and postoperative dimensions of the ridge. For edentulous patients, studies were included when providing the data on ridge and defect description, or the amount of augmentation achieved. The search yielded 53 publications for partially edentulous patients and 15 publications for edentulous patients. The literature provides evidence that dehiscence and fenestrations can be treated successfully with guided bone regeneration (GBR) at the time of implant placement (mean implant survival rate (MISR) 92.2%, mean complication rate (MCR) 4.99%). In partially edentulous ridges, when a horizontal defect is present, procedures such as staged GBR (MISR 100%, MCR 11.9%), bone block grafts (MISR 98.4%, MCR 6.3%), and ridge expansion/splitting (MISR 97.4%, MCR 6.8%) have proved to be effective. Vertical defects can be treated with simultaneous and staged GBR (MISR 98.9%, MCR 13.1% and MISR 100%, MCR 6.95%, respectively), bone block grafts (MISR 96.3%, MCR 8.1%), and distraction osteogenesis (MISR 98.2%, MCR 22.4%). In edentulous patients, there is evidence that bone block grafts can be used (MISR 87.75%), and that Le Fort I osteotomies can be applied (MISR 87.9%), but associated with a high complication rate. The objective of extracting specific indications for each

  13. The Caldwell-Luc procedure: institutional review of 670 cases: 1975-1985.

    PubMed

    DeFreitas, J; Lucente, F E

    1988-12-01

    The Caldwell-Luc procedure, which has long been fundamental in the treatment of perisinus disease, has undergone increasing scrutiny when used for inflammatory antritis. Individual morbidity rates of less than 10% to greater than 40% have been reported. To assess the data from our own institution, a retrospective study of 670 Caldwell-Luc procedures was undertaken. Patients ranged in age from 10 to 82, with a mean age of 42.9 years. There were 271 males and 325 females. Parameters studied included symptoms, physical findings, operative techniques, surgical findings, length of hospitalization, and postoperative complications. Immediate postoperative complications included facial swelling in 89% of patients, cheek discomfort in 33%, significant hemorrhage in 2.9%, and temperature elevation in 12.1%. Long-term follow-up ranged from 2 years to 10 years. Overall complication rates in 464 patients included facial asymmetry (3), facial numbness or paresthesia (42), oroantral fistulas (5), gingivolabial wound dehiscences (7), dacryocystitis (12), devitalized tooth (2), recurrent sinusitis (56), and recurrent polyposis (25). A revision antrostomy was required in 37 patients, a revision Caldwell-Luc in 22 patients, an intranasal sphenoethmoidectomy in 17, and root canal therapy in 2 patients. The most frequent complication was recurrent nasal obstruction, occurring in 28% of patients. Overall complication rates tended to increase with a longer follow-up period. PMID:3200074

  14. A critical review of second law costing methods - II; Calculus procedures

    SciTech Connect

    Gaggioli, R.A. ); ElSayed, Y.M. )

    1989-03-01

    This article completes the review of the development and state of engineering economic applications of the Second Law of Thermodynamics. The authors began with a historical review, followed by a brief discussion of the relevant cost accounting concepts and, in turn, general descriptions of the different exergy costing methods which are in existence. Then, the various algebraic techniques of exergy costing were analyzed and critiqued, generally by considering successive publications developing and/or based on a technique. This paper is devoted primarily to calculus methods. The algebraic and calculus techniques relate to each other, and those relationships are developed here. Furthermore, general concepts, discussion and conclusions which are relevant to both algebraic and calculus methods are presented, along with suggestions regarding further research.

  15. Perioperative atrial fibrillation: A systematic review of evolving therapeutic options in pharmacologic and procedural management

    PubMed Central

    Schleifer, J. William; Ramakrishna, Harish

    2015-01-01

    Given the high incidence of atrial fibrillation (AF) in the surgical population and the associated morbidity, physicians managing these complicated patients in the perioperative period need to be aware of the new and emerging trends in its therapy. The cornerstones of AF management have always been rate/rhythm control as well as anticoagulation. Restoration of sinus rhythm remains the fundamental philosophy as it maintains the atrial contribution to cardiac output and improves ventricular function. The recent years have seen a dramatic increase in the number of randomized AF trials that have made significant advances to our understanding of both pharmacologic and procedural management, from the introduction of the new generation of oral anticoagulants (NOAC's) to catheter approaches for AF ablation. This paper will summarize the newest data that will affect the perioperative management of these patients. PMID:26440243

  16. A focused review on acne-induced and aesthetic procedure-related postinflammatory hyperpigmentation in Asians.

    PubMed

    Eimpunth, S; Wanitphadeedecha, R; Manuskiatti, W

    2013-01-01

    Postinflammatory hyperpigmentation (PIH) is a common consequence following cutaneous inflammation in dark-skinned individuals with Fitzpatrick skin phototypes (SPTs) III-VI. The exact pathogenesis of this condition is unknown, but is believed to be an integral part of the normal response of the skin to inflammatory stimuli. PIH can last from months to years and may significantly impair quality of life of affected individuals. The primary treatment of PIH is prevention and treatment of the underlying inflammatory condition. In addition to prevention, there are a variety of medication and procedures used to treat PIH. Although topical skin-depigmenting agents remain the treatment of choice for PIH, lasers and light sources may be an effective adjunctive therapy or alternative for treatment failures. When treating PIH, any treatment options selected should be optimized and utilized carefully because the treatments itself may worsen the PIH. PMID:23205540

  17. Piezosurgery in Bone Augmentation Procedures Previous to Dental Implant Surgery: A Review of the Literature

    PubMed Central

    Magrin, Gabriel Leonardo; Sigua-Rodriguez, Eder Alberto; Goulart, Douglas Rangel; Asprino, Luciana

    2015-01-01

    The piezosurgery has been used with increasing frequency and applicability by health professionals, especially those who deal with dental implants. The concept of piezoelectricity has emerged in the nineteenth century, but it was applied in oral surgery from 1988 by Tomaso Vercellotti. It consists of an ultrasonic device able to cut mineralized bone tissue, without injuring the adjacent soft tissue. It also has several advantages when compared to conventional techniques with drills and saws, such as the production of a precise, clean and low bleed bone cut that shows positive biological results. In dental implants surgery, it has been used for maxillary sinus lifting, removal of bone blocks, distraction osteogenesis, lateralization of the inferior alveolar nerve, split crest of alveolar ridge and even for dental implants placement. The purpose of this paper is to discuss the use of piezosurgery in bone augmentation procedures used previously to dental implants placement. PMID:26966469

  18. Critical review of some multivariate procedures in the analysis of geochemical data

    USGS Publications Warehouse

    Miesch, A.T.

    1969-01-01

    Simulation experiments have been conducted to examine the potential usefulness of R-mode and Q-mode factor methods in the analysis and interpretation of geochemical data. The R-mode factor analysis experiment consisted of constructing a factor model, using the model to generate a correlation matrix, and attempting to recover the model by R-mode techniques. The techniques were successful in determining the number of factors in the model, but the factor loadings could not be estimated even approximately on the basis of mathematical procedures alone. Q-mode factor methods were successful in recovering all of the properties of a model used to generate hypothetical chemical data on olivine samples, but it was necessary to use a correction previously regarded as unimportant. ?? 1969 Plenum Publishing Corporation.

  19. The behavioral economics of drug self-administration: A review and new analytical approach for within-session procedures

    PubMed Central

    Bentzley, Brandon S.; Fender, Kimberly M.; Aston-Jones, Gary

    2012-01-01

    Rationale Behavioral-economic demand curve analysis offers several useful measures of drug self-administration. Although generation of demand curves previously required multiple days, recent within-session procedures allow curve construction from a single 110-min cocaine self-administration session, making behavioral-economic analyses available to a broad range of self-administration experiments. However, a mathematical approach of curve fitting has not been reported for the within-session threshold procedure. Objectives We review demand curve analysis in drug self-administration experiments and provide a quantitative method for fitting curves to single-session data that incorporates relative stability of brain drug concentration. Methods Sprague-Dawley rats were trained to self-administer cocaine, and then tested with the threshold procedure in which the cocaine dose was sequentially decreased on a fixed ratio-1 schedule. Price points (responses/mg cocaine) outside of relatively stable brain cocaine concentrations were removed before curves were fit. Curve-fit accuracy was determined by the degree of correlation between graphical and calculated parameters for cocaine consumption at low price (Q0) and the price at which maximal responding occurred (Pmax). Results Removing price points that occurred at relatively unstable brain cocaine concentrations generated precise estimates of Q0 and resulted in Pmax values with significantly closer agreement with graphical Pmax than conventional methods. Conclusion The exponential demand equation can be fit to single-session data using the threshold procedure for cocaine self-administration. Removing data points that occur during relatively unstable brain cocaine concentrations resulted in more accurate estimates of demand curve slope than graphical methods, permitting a more comprehensive analysis of drug self-administration via a behavioral-economic framework. PMID:23086021

  20. Regional anesthesia for pediatric knee surgery: a review of the indications, procedures, outcomes, safety, and challenges

    PubMed Central

    Muhly, Wallis T; Gurnaney, Harshad G; Ganesh, Arjunan

    2015-01-01

    The indications for surgery on the knee in children and adolescents share some similarity to adult practice in that there are an increasing number of sports-related injuries requiring surgical repair. In addition, there are some unique age-related conditions or congenital abnormalities that may present as indications for orthopedic intervention at the level of the knee. The efficacy and safety of peripheral nerve blocks (PNBs) for postoperative analgesia following orthopedic surgery has been well established in adults. Recent studies have also demonstrated earlier functional recovery after surgery in patients who received PNBs. In children, PNB is gaining popularity, and increasing data are emerging to demonstrate the feasibility, efficacy, and safety in this population. In this paper, we will review some of the most common indications for surgery involving the knee in children and the anatomy of knee, associated dermatomal and osteotomal innervation, and the PNBs most commonly used to produce analgesia at the level of the knee. We will review the evidence in support of regional anesthesia in children in terms of both the quality conferred to the immediate postoperative care and the role of continuous PNBs in maintaining effective analgesia following discharge. Also we will discuss some of the subtle challenges in utilizing regional anesthesia in the pediatric patient including the use of general anesthesia when performing regional anesthesia and the issue of monitoring for compartment syndrome. Finally, we will offer some thoughts about areas of practice that are in need of further investigation. PMID:26609245

  1. Critical review: life-cycle inventory procedures for long-term release of metals.

    PubMed

    Pettersen, Johan; Hertwich, Edgar G

    2008-07-01

    Life-cycle assessment (LCA) is the method of inventorying, assessing, and interpreting environmental interventions caused by products and product systems through their life cycle. The ecotoxicity of metals has proven a challenge for LCA given metal characteristics such as reversibility of removal processes, speciation, and the effect on bioavailability and ecotoxic effect assessment. Our review focuses on the first part of the ecotoxic impact chain for metals, i.e., the release of metals from solid deposits. According to the principle of temporal justice, sustainability assessment tools such as LCA should accountfor emissions regardless of temporal location distribution. This is in LCA commonly interpreted as leaching until depletion of metals bound in solid wastes under the presumption that infinite time implies infinite weathering. This approach is risk conservative for metals and it hampers the use of LCA to assess remediation projects for soils and sediments contaminated by inorganic substances. We discuss metal significance and inventory issues in LCA, and review existing and proposed approachesto make LCA applicable to metal long-term emission. PMID:18677985

  2. Review of preparative and analytical procedures for the study of proteins in grape juice and wine.

    PubMed

    Le Bourse, D; Jégou, S; Conreux, A; Villaume, S; Jeandet, P

    2010-05-14

    Proteins have a great influence on wine quality as they exhibit a various range of properties. In fact, they are involved among others in white wine turbidity, organoleptic characteristics and foam formation in sparkling wines. These compounds could also be of major interest for varietal differentiation, regarding wine authentication and traceability issues. To provide a better understanding of the role played by these biomolecules in wine processing and explore their potential applications, there is a manifest need for the quantification and characterization of each individual one in terms of sequence, structure and intrinsic and functional properties. We thus present an overview of preparative and analytical methods for the study of proteins in grape juices and wines, from routine techniques to dedicated methodologies. They include sample preparation with chromatographic methods for the purification and identification of proteins, quantification protocols and characterization procedures such as electrophoretic techniques, immunological methods, sequencing, mass spectrometry, physico-chemical and structural analyses, and so on. We expose advantages and limits of each technique and focus on the different but complementary information they can provide. Despite the past years advances in the field proteins identification, the elucidation of the full protein profile for grape juices and wines remains strenuous. Their interactions with other wine compounds make the challenge even harder. We therefore emphasize the requirement of the techniques to be refined and suggest the developments to be expected. PMID:20441863

  3. Traumatic Extensor Tendon Injuries to the Hand: Clinical Anatomy, Biomechanics, and Surgical Procedure Review.

    PubMed

    Colzani, Giulia; Tos, Pierluigi; Battiston, Bruno; Merolla, Giovanni; Porcellini, Giuseppe; Artiaco, Stefano

    2016-04-01

    The extensor apparatus is a complex muscle-tendon system that requires integrity or optimal reconstruction to preserve hand function. Anatomical knowledge and the understanding of physiopathology of extensor tendons are essential for an accurate diagnosis of extensor tendon injuries (ETIs) of the hand and wrist, because these lesions are complex and commonly observed in clinical practice. A careful clinical history and assessment still remain the first step for the diagnosis, followed by US and MR to confirm the suspect of ETI or to investigate some doubtful conditions and rule out associate lesions. During last decades the evolution of surgical techniques and rehabilitative treatment protocol led to gradual improvement in clinical results of ETI treatment and surgical repair. Injury classification into anatomical zones and the evaluation of the characteristics of the lesions are considered key points to select the appropriate treatment for ETI. Both conservative and surgical management can be indicated in ETI, depending on the anatomical zone and on the characteristics of the injuries. As a general rule, an attempt of conservative treatment should be performed when the lesion is expected to have favorable result with nonoperative procedure. Many surgical techniques have been proposed over the time and with favorable results if the tendon injury is not underestimated and adequately treated. Despite recent research findings, a lack of evidence-based knowledge is still observed in surgical treatment and postoperative management of ETI. Further clinical and biomechanical investigations would be advisable to clarify this complex issue. PMID:27616821

  4. A systematic review of minimally invasive surgical treatment for atrial fibrillation: a comparison of the Cox-Maze procedure, beating-heart epicardial ablation, and the hybrid procedure on safety and efficacy.

    PubMed

    Je, Hyung Gon; Shuman, Deborah J; Ad, Niv

    2015-10-01

    There is a growing trend to perform off-bypass surgical ablation for atrial fibrillation (AF) because it is perceived to be safer and more effective than the Cox-Maze procedure with cardiopulmonary bypass (CPB) support. In this systematic review, we compared three minimally invasive stand-alone surgical ablation procedures for AF: the endocardial Cox-Maze procedure, epicardial surgical ablation and a hybrid epicardial surgical and catheter-based endocardial ablation procedure (hybrid procedure). Relevant studies were identified in MEDLINE and the Cochrane Database of Systematic Reviews according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. From 565 initial studies, 37 were included in this review. The total number of patients across all studies was 1877 (range 10-139). Two studies reported on endocardial Cox-Maze procedures (n = 145), 26 reported on epicardial surgical ablation (n = 1382) and 9 reported on hybrid surgical ablation (n = 350). For minimally invasive Cox-Maze, epicardial and hybrid groups, operative mortality rates were 0, 0.5 and 0.9%, perioperative permanent pacemaker insertion rates were 3.5, 2.7 and 1.5%, incidence of conversion to median sternotomy was 0, 2.4 and 2.5%, and reoperation for bleeding was 1.0, 1.5 and 2.2%, with mean length of stay (days) of 5.4, 6.0 and 4.6, respectively. At 12 months, rates of sinus rhythm restoration were 93, 80 and 70%, and sinus restoration without anti-arrhythmic medications was 87, 72 and 71%, for Cox-Maze, epicardial and hybrid procedures, respectively. Of the three procedures, the minimally invasive Cox-Maze procedure with CPB support was most effective for the treatment of stand-alone AF and had important safety advantages in conversion to sternotomy and major bleeding. The minimally invasive Cox-Maze procedure with CPB support also demonstrated the potential for a higher success rate 12 months following the procedure. PMID:25567961

  5. Remote detection of water stress conditions via a diurnal photochemical reflectance index (PRI) improves yield prediction in rainfed wheat

    NASA Astrophysics Data System (ADS)

    Magney, T. S.; Vierling, L. A.; Eitel, J.

    2014-12-01

    Employing remotely sensed techniques to quantify the existence and magnitude of midday photosynthetic downregulation using the photochemical reflectance index (PRI) may reveal new information about plant responses to abiotic stressors in space and time. However, the interpretation and application of the PRI can be confounded because of its sensitivity to several variables changing at the diurnal (e.g., irradiation, shadow fraction) and seasonal (e.g., leaf area, chlorophyll and carotene pigment concentrations, irradiation) time scales. We explored different techniques to correct the PRI for variations in canopy structure and relative chlorophyll content (ChlR) using highly temporally resolved (frequency = five minutes) in-situ radiometric measurements of PRI and the Normalized Difference Vegetation Index (NDVI) over eight soft white spring wheat (Triticum aestivum L.)field plots under varying nitrogen and soil water conditions over two seasons. Our results suggest that the influence of seasonal variation in canopy ChlR and LAI on the diurnally measured PRI (PRIdiurnal) can be minimized using simple correction techniques, therefore improving the strength of PRI as a tool to quantify abiotic stressors such as daily changes in soil volumetric water content (SVWC), and vapor pressure deficit (VPD). PRIdiurnal responded strongly to available nitrogen, and linearly tracked seasonal changes in SVWC, VPD, and stomatal conductance (gc). Utilizing the PRI as an indicator of stress, yield predictions significantly over greenness indices such as the NDVI. This study provides insight towards the future interpretation and scaling of PRI to quantify rapid changes in photosynthesis, and as an indicator of plant stress.

  6. A review of combined experimental and computational procedures for assessing biopolymer structure–process–property relationships

    PubMed Central

    Gronau, Greta; Krishnaji, Sreevidhya T.; Kinahan, Michelle E.; Giesa, Tristan; Wong, Joyce Y.; Kaplan, David L.; Buehler, Markus J.

    2013-01-01

    Tailored biomaterials with tunable functional properties are desirable for many applications ranging from drug delivery to regenerative medicine. To improve the predictability of biopolymer materials functionality, multiple design parameters need to be considered, along with appropriate models. In this article we review the state of the art of synthesis and processing related to the design of biopolymers, with an emphasis on the integration of bottom-up computational modeling in the design process. We consider three prominent examples of well-studied biopolymer materials – elastin, silk, and collagen – and assess their hierarchical structure, intriguing functional properties and categorize existing approaches to study these materials. We find that an integrated design approach in which both experiments and computational modeling are used has rarely been applied for these materials due to difficulties in relating insights gained on different length- and time-scales. In this context, multiscale engineering offers a powerful means to accelerate the biomaterials design process for the development of tailored materials that suit the needs posed by the various applications. The combined use of experimental and computational tools has a very broad applicability not only in the field of biopolymers, but can be exploited to tailor the properties of other polymers and composite materials in general. PMID:22938765

  7. Authorship and responsibility in health sciences research: a review of procedures for fairly allocating authorship in multi-author studies.

    PubMed

    Smith, Elise; Williams-Jones, Bryn

    2012-06-01

    While there has been significant discussion in the health sciences and ethics literatures about problems associated with publication practices (e.g., ghost- and gift-authorship, conflicts of interest), there has been relatively little practical guidance developed to help researchers determine how they should fairly allocate credit for multi-authored publications. Fair allocation of credit requires that participating authors be acknowledged for their contribution and responsibilities, but it is not obvious what contributions should warrant authorship, nor who should be responsible for the quality and content of the scientific research findings presented in a publication. In this paper, we review arguments presented in the ethics and health science literatures, and the policies or guidelines proposed by learned societies and journals, in order to explore the link between author contribution and responsibility in multi-author multidisciplinary health science publications. We then critically examine the various procedures used in the field to help researchers fairly allocate authorship. PMID:21312000

  8. Road-corridor planning in the EIA procedure in Spain. A review of case studies

    SciTech Connect

    Loro, Manuel [Department of Urban and Regional Planning and Environment, Civil Engineering School, Universidad Politécnica de Madrid, Prof. Aranguren s Transport Research Centre Universidad Politécnica de Madrid, ETSI Caminos, Canales y Puertos, Prof. Aranguren s Centro de investigación del transporte, TRANSyT-UPM, ETSI Caminos, Canales y Puertos, Universidad Politécnica de Madrid, Prof. Aranguren s Arce, Rosa M. [Department of Urban and Regional Planning and Environment, Civil Engineering School, Universidad Politécnica de Madrid, Prof. Aranguren s Transport Research Centre Universidad Politécnica de Madrid, ETSI Caminos, Canales y Puertos, Prof. Aranguren s Centro de investigación del transporte, TRANSyT-UPM, ETSI Caminos, Canales y Puertos, Universidad Politécnica de Madrid, Prof. Aranguren s Ortega, Emilio [Transport Research Centre Universidad Politécnica de Madrid, ETSI Caminos, Canales y Puertos, Prof. Aranguren s Centro de investigación del transporte, TRANSyT-UPM, ETSI Caminos, Canales y Puertos, Universidad Politécnica de Madrid, Prof. Aranguren s Department of Construction and Rural Roads, Forestry Engineering School, Universidad Politécnica de Madrid, Ciudad Universitaria s and others

    2014-01-15

    The assessment of different alternatives in road-corridor planning must be based on a number of well-defined territorial variables that serve as decision making criteria, and this requires a high-quality preliminary environmental assessment study. In Spain the formal specifications for the technical requirements stipulate the constraints that must be considered in the early stages of defining road corridors, but not how they should be analyzed and ranked. As part of the feasibility study of a new road definition, the most common methodology is to establish different levels of Territorial Carrying Capacity (TCC) in the study area in order to summarize the territorial variables on thematic maps and to ease the tracing process of road-corridor layout alternatives. This paper explores the variables used in 22 road-construction projects conducted by the Ministry of Public Works that were subject to the Spanish EIA regulation and published between 2006 and 2008. The aim was to evaluate the quality of the methods applied and the homogeneity and suitability of the variables used for defining the TCC. The variables were clustered into physical, environmental, land-use and cultural constraints for the purpose of comparing the TCC values assigned in the studies reviewed. We found the average quality of the studies to be generally acceptable in terms of the justification of the methodology, the weighting and classification of the variables, and the creation of a synthesis map. Nevertheless, the methods for assessing the TCC are not sufficiently standardized; there is a lack of uniformity in the cartographic information sources and methodologies for the TCC valuation. -- Highlights: • We explore 22 road-corridor planning studies subjected to the Spanish EIA regulation. • We analyze the variables selected for defining territorial carrying capacity. • The quality of the studies is acceptable (methodology, variable weighting, mapping). • There is heterogeneity in the

  9. Transcatheter Valve Implantation in Failed Surgically Inserted Bioprosthesis: Review and Practical Guide to Echocardiographic Imaging in Valve-in-Valve Procedures.

    PubMed

    Hamid, Nadira B; Khalique, Omar K; Monaghan, Mark J; Kodali, Susheel K; Dvir, Danny; Bapat, Vinayak N; Nazif, Tamim M; Vahl, Torsten; George, Isaac; Leon, Martin B; Hahn, Rebecca T

    2015-08-01

    An increased use of bioprosthetic heart valves has stimulated an interest in possible transcatheter options for bioprosthetic valve failure given the high operative risk. The encouraging results of transcatheter aortic valve implantation in high-risk surgical candidates with native disease have led to the development of the transcatheter valve-in-valve (VIV) procedures for failed bioprostheses. VIV procedures are unique in many ways, and there is an increased need for multimodality imaging in a team-based approach. The echocardiographic approach to VIV procedures has not previously been described. In this review, we summarize key echocardiographic requirements for optimal patient selection, procedural guidance, and immediate post-procedural assessment for VIV procedures. PMID:26271092

  10. Are existing procedures enough? Image and video quality assessment: review of subjective and objective metrics

    NASA Astrophysics Data System (ADS)

    Ouni, Sonia; Chambah, Majed; Herbin, Michel; Zagrouba, Ezzeddine

    2008-01-01

    Images and videos are subject to a wide variety of distortions during acquisition, digitizing, processing, restoration, compression, storage, transmission and reproduction, any of which may result in degradation in visual quality. That is why image quality assessment plays a major role in many image processing applications. Image and video quality metrics can be classified by using a number of criteria such as the type of the application domain, the predicted distortion (noise, blur, etc.) and the type of information needed to assess the quality (original image, distorted image, etc.). In the literature, the most reliable way of assessing the quality of an image or of a video is subjective evaluation [1], because human beings are the ultimate receivers in most applications. The subjective quality metric, obtained from a number of human observers, has been regarded for many years as the most reliable form of quality measurement. However, this approach is too cumbersome, slow and expensive for most applications [2]. So, in recent years a great effort has been made towards the development of quantitative measures. The objective quality evaluation is automated, done in real time and needs no user interaction. But ideally, such a quality assessment system would perceive and measure image or video impairments just like a human being [3]. The quality assessment is so important and is still an active and evolving research topic because it is a central issue in the design, implementation, and performance testing of all systems [4, 5]. Usually, the relevant literature and the related work present only a state of the art of metrics that are limited to a specific application domain. The major goal of this paper is to present a wider state of the art of the most used metrics in several application domains such as compression [6], restoration [7], etc. In this paper, we review the basic concepts and methods in subjective and objective image/video quality assessment research and

  11. A review of downscaling procedures - a contribution to the research on climate change impacts at city scale

    NASA Astrophysics Data System (ADS)

    Smid, Marek; Costa, Ana; Pebesma, Edzer; Granell, Carlos; Bhattacharya, Devanjan

    2016-04-01

    Human kind is currently predominantly urban based, and the majority of ever continuing population growth will take place in urban agglomerations. Urban systems are not only major drivers of climate change, but also the impact hot spots. Furthermore, climate change impacts are commonly managed at city scale. Therefore, assessing climate change impacts on urban systems is a very relevant subject of research. Climate and its impacts on all levels (local, meso and global scale) and also the inter-scale dependencies of those processes should be a subject to detail analysis. While global and regional projections of future climate are currently available, local-scale information is lacking. Hence, statistical downscaling methodologies represent a potentially efficient way to help to close this gap. In general, the methodological reviews of downscaling procedures cover the various methods according to their application (e.g. downscaling for the hydrological modelling). Some of the most recent and comprehensive studies, such as the ESSEM COST Action ES1102 (VALUE), use the concept of Perfect Prog and MOS. Other examples of classification schemes of downscaling techniques consider three main categories: linear methods, weather classifications and weather generators. Downscaling and climate modelling represent a multidisciplinary field, where researchers from various backgrounds intersect their efforts, resulting in specific terminology, which may be somewhat confusing. For instance, the Polynomial Regression (also called the Surface Trend Analysis) is a statistical technique. In the context of the spatial interpolation procedures, it is commonly classified as a deterministic technique, and kriging approaches are classified as stochastic. Furthermore, the terms "statistical" and "stochastic" (frequently used as names of sub-classes in downscaling methodological reviews) are not always considered as synonymous, even though both terms could be seen as identical since they are

  12. Use of Tumescence for Outpatient Abdominoplasty and Other Concurrent Body Contouring Procedures: A Review of 65 Consecutive Patients

    PubMed Central

    Holzman, Nathaniel L.; Singh, Mansher; Caterson, Stephanie A.; Eriksson, Elof

    2015-01-01

    Introduction: Abdominoplasty is being increasingly performed as an outpatient procedure. The role of tumescent technique in decreasing postoperative pain and hospital stay has not been extensively studied. Methods: We reviewed 65 consecutive patients who underwent tumescent abdominoplasty over 20 months by a single surgeon. All the patients were followed up for at least 1 year. The outcomes were evaluated in terms of systemic complications such as deep vein thrombosis and pulmonary embolism and local complications such as seroma, wound infection, and skin necrosis. Results: Of the 65 patient records analyzed, 61 were of females and 4 of males. Average age for the patient population was 45.2 years. Mean follow-up was at least 1 year for all the patients. Ninety-five percent of patients could be discharged the same day with tumescent abdominoplasty, whereas 71% of the patients who underwent concurrent procedures with abdominoplasty were also able to go home the same day. All the patients reported excellent postoperative pain control. There was no report of deep vein thrombosis or pulmonary embolism in any of these patients. Wound complications occurred in 14 patients (21.6%), of which 12 patients had seroma (18.5%) and 2 had wound infection (3.1%). The seromas were treated with repeated aspirations or Jackson-Pratt drain placement, whereas the wound infections resolved with outpatient antibiotics. Conclusions: The safety and efficiency of outpatient abdominoplasty can be further facilitated by utilizing tumescence. Tumescence helps the patients be discharged sooner, usually the same day, mobilize sooner, and rely less on oral narcotics at home. PMID:26366244

  13. Successful Management of Two Cases of Placenta Accreta and a Literature Review: Use of the B-Lynch Suture and Bilateral Uterine Artery Ligation Procedures

    PubMed Central

    Arab, Maliheh; Ghavami, Behnaz; Saraeian, Samaneh; Sheibani, Samaneh; Abbasian Azar, Fatemeh; Hosseini-Zijoud, Seyed-Mostafa

    2016-01-01

    Introduction Placenta accreta is an increasingly common complication of pregnancy that can result in massive hemorrhage. Case Presentation We describe two cases of placenta accreta, with successful conservative management in a referral hospital in Tehran, Iran. In both cases, two procedures were performed: compression suture (B-Lynch) and a perfusion-decreasing procedure (bilateral uterine artery ligation). We also present the results of a narrative literature review. Conclusions The double B-Lynch and uterine arterial ligation procedure in cases of abnormal placentation might be strongly considered in fertility preservation, coagulopathy, coexisting medical disease, blood access shortage, low surgical experience, distant local hospitals, and no help. PMID:27354921

  14. The crystal structure of Neisseria gonorrhoeae PriB reveals mechanistic differences among bacterial DNA replication restart pathways

    SciTech Connect

    Dong, Jinlan; George, Nicholas P.; Duckett, Katrina L.; DeBeer, Madeleine A.P.; Lopper, Matthew E.

    2010-05-25

    Reactivation of repaired DNA replication forks is essential for complete duplication of bacterial genomes. However, not all bacteria encode homologs of the well-studied Escherichia coli DNA replication restart primosome proteins, suggesting that there might be distinct mechanistic differences among DNA replication restart pathways in diverse bacteria. Since reactivation of repaired DNA replication forks requires coordinated DNA and protein binding by DNA replication restart primosome proteins, we determined the crystal structure of Neisseria gonorrhoeae PriB at 2.7 {angstrom} resolution and investigated its ability to physically interact with DNA and PriA helicase. Comparison of the crystal structures of PriB from N. gonorrhoeae and E. coli reveals a well-conserved homodimeric structure consisting of two oligosaccharide/oligonucleotide-binding (OB) folds. In spite of their overall structural similarity, there is significant species variation in the type and distribution of surface amino acid residues. This correlates with striking differences in the affinity with which each PriB homolog binds single-stranded DNA and PriA helicase. These results provide evidence that mechanisms of DNA replication restart are not identical across diverse species and that these pathways have likely become specialized to meet the needs of individual organisms.

  15. Blocking the maturation of OncomiRNAs using pri-miRNA-17∼92 aptamer in retinoblastoma.

    PubMed

    Subramanian, Nithya; Kanwar, Jagat R; Kanwar, Rupinder K; Krishnakumar, Subramanian

    2015-02-01

    The miR-17∼92. or oncomiR-1, cluster encodes oncogenic microRNAs (miRNAs), and it also promotes retinoblastoma (RB) tumor formation. Antagomir and miRNA mimics based approaches are widely tried against oncogenic and tumor suppressive miRNAs. Other methods for targeting cancer related miRNAs are still under development. In the current study, we focused on the pri-miRNA-17∼92 aptamer (pri-apt), which can potentially replace the mix of five antagomirs by one aptamer that function to abrogate the maturation of miR-17, miR-18a, and miR-19b (P<0.05) for targeting RB. We used RB cell lines WERI-Rb1 and Y79 as an in vitro model. Cellular changes upon transfecting the pri-apt led to S-phase arrest in WERI-Rb1 cells and onset of apoptosis in both Y79 and WERI-Rb1 cell lines. There was increased cytotoxicity as measured by lactate dehydrogenase activity in pri-apt treated Y79 cells (P<0.05), and significant inhibition of cell proliferation was observed in both of the cell lines. Thus we showed the antiproliferative property of pri-apt in RB cell lines, which can be readily modified by developing appropriate vectors for the delivery of the aptamer specifically to cancer cells. PMID:25513843

  16. Blocking the Maturation of OncomiRNAs Using pri-miRNA-17∼92 Aptamer in Retinoblastoma

    PubMed Central

    Subramanian, Nithya; Kanwar, Jagat R.; Kanwar, Rupinder K.

    2015-01-01

    The miR-17∼92. or oncomiR-1, cluster encodes oncogenic microRNAs (miRNAs), and it also promotes retinoblastoma (RB) tumor formation. Antagomir and miRNA mimics based approaches are widely tried against oncogenic and tumor suppressive miRNAs. Other methods for targeting cancer related miRNAs are still under development. In the current study, we focused on the pri-miRNA-17∼92 aptamer (pri-apt), which can potentially replace the mix of five antagomirs by one aptamer that function to abrogate the maturation of miR-17, miR-18a, and miR-19b (P<0.05) for targeting RB. We used RB cell lines WERI-Rb1 and Y79 as an in vitro model. Cellular changes upon transfecting the pri-apt led to S-phase arrest in WERI-Rb1 cells and onset of apoptosis in both Y79 and WERI-Rb1 cell lines. There was increased cytotoxicity as measured by lactate dehydrogenase activity in pri-apt treated Y79 cells (P<0.05), and significant inhibition of cell proliferation was observed in both of the cell lines. Thus we showed the antiproliferative property of pri-apt in RB cell lines, which can be readily modified by developing appropriate vectors for the delivery of the aptamer specifically to cancer cells. PMID:25513843

  17. Peri- and intraarticular analgesia (PIA) superior to other procedures in TKA – review of literature and results of own RCT

    PubMed Central

    Beckmann, J.; Stathellis, A.; Fitz, W.; Köck, F.; Bauer, G.; Gebauer, M.; Schnurr, C.

    2016-01-01

    Background: TKA is a worldwide established surgery with periarticular infiltrations being scientifically funded is the superiority of in the perioperative setup of TKA nowadays. However, nerve blocks are still widely used as perioperative standard meaning possible analgesia beyond surger, but simultaneously with sensomotoric deficiency and resulting risk of fall as well as increased pain after removal of nerval catheters. Also a standard procedure is intubation which means immediate pain after awakening of patients with resulting need for sufficient oral, intravenous, intramuscular or subcutaneous analgesia. We present an actual review of the literature and an own RCT comparing infiltrations with nerve blocks, which to our best knowledge presents the first RCT combined with an additional continous part. Methods: Literature review (PubMed)Own RCT: 50 TKA were randomized and prospectively included. 25 patients received nerve blocks with a single ischiadicus block and a femoralis block with additional perineural catheter. 25 patients received periarticular infiltrations together with an intraarticular catheter (PIA). All catheters stayed for 4 days. Both groups received a laryngeal masc. Postoperative mobilisation, surgeon and type of prosthesis were the same in all patients. The following was evaluated pre- and postoperatively (first, third and sixth hour, first until sixth day): VAS, additional analgetics/ opioids, KSS score, knee function and ability to raise the straightened leg. Complications as infection, falls, DVT etc. were recorded. Results: Periarticular infiltrations are superior to other options in the perioperative setup of TKA which is clearly shown by literature (several studies including reviews) as well as the results of our own RCT: Pain occured in both groups, however, VAS, additional analgetics/ opioids and KSS score as well as the ability to raise the straightened leg were significantly better following PIA (p<0,01), with comparable knee function

  18. iStent as a Solo Procedure for Glaucoma Patients: A Systematic Review and Meta-Analysis

    PubMed Central

    Malvankar-Mehta, Monali S.; Chen, Yufeng Nancy; Iordanous, Yiannis; Wang, Wan Wendy; Costella, John; Hutnik, Cindy M. L.

    2015-01-01

    Background Glaucoma is a leading cause of irreversible blindness. It is firmly entrenched in the traditional treatment paradigm to start with pharmacotherapy. However, pharmacotherapy is not benign and has been well documented to have a number of significant challenges. Minimally invasive glaucoma surgery (MIGS) that targets the outflow pathway with minimal to no scleral dissection has resulted in the need to reconsider the glaucoma treatment paradigm. Purpose To perform a systematic review and meta-analysis to evaluate and quantify the effect on post-operative intraocular pressure (IOP) and number of topical glaucoma medications, in patients receiving the iStent MIGS device as the solo procedure without concurrent cataract surgery. Methods A systematic review was conducted by searching various databases between January 1, 2000, and June 30, 2014. Studies reporting up to a maximum follow-up period of 24 months were retrieved and screened using the EPPI-Reviewer 4 gateway. Percentage reduction in IOP (IOPR%), and mean reduction in topical glaucoma medications after surgery were computed. Meta-analysis was performed using STATA v. 13.0. The standardized mean difference (SMD) was calculated as the effect size for continuous scale outcomes. Heterogeneity was determined using the I2 statistics, Z-value, and χ2 statistics. Fixed-effect and random-effect models were developed based on heterogeneity. Sub-group analysis was performed based on the number of iStents implanted and the follow-up period. The outcome measures were changes in the IOP and number of glaucoma medications. Results The search strategy identified 105 records from published literature and 9 records from the grey literature. Five studies with 248 subjects were included for quantitative synthesis. A 22% IOP reduction (IOPR%) from baseline occurred at 18-months after one iStent implant, 30% at 6-months after two iStents implantations, and 40% at 6-months after implantation of three iStents. A mean

  19. 26 CFR 301.6103(p)(7)-1 - Procedures for administrative review of a determination that an authorized recipient has failed...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... determination that an authorized recipient has failed to safeguard returns or return information. 301.6103(p)(7)-1 Section 301.6103(p)(7)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Records § 301.6103(p)(7)-1 Procedures for administrative review of a determination that an...

  20. 26 CFR 301.6103(p)(7)-1 - Procedures for administrative review of a determination that an authorized recipient has failed...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... determination that an authorized recipient has failed to safeguard returns or return information. 301.6103(p)(7)-1 Section 301.6103(p)(7)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Records § 301.6103(p)(7)-1 Procedures for administrative review of a determination that an...