Sample records for rodent housing rooms

  1. Sound levels in modern rodent housing rooms are an uncontrolled environmental variable with fluctuations mainly due to human activities

    PubMed Central

    Lauer, Amanda M.; May, Bradford J.; Hao, Ziwei Judy; Watson, Julie

    2009-01-01

    Noise in animal housing facilities is an environmental variable that can affect hearing, behavior and physiology in mice. The authors measured sound levels in two rodent housing rooms (room 1 and room 2) during several periods of 24 h. Room 1, which was subject to heavy personnel traffic, contained ventilated racks and static cages that housed large numbers of mice. Room 2 was accessed by only a few staff members and contained only static cages that housed fewer mice. In both rooms, background sound levels were about 80 dB, and transient noises caused sound levels to temporarily rise 30–40 dB above the baseline level; such peaks occurred frequently during work hours (8:30 AM to 4:30 PM) and infrequently during non-work hours. Noise peaks during work hours in room 1 occurred about two times as often as in room 2 (P = 0.01). Use of changing stations located in the rooms caused background noise to increase by about 10 dB. Loud noise and noise variability were attributed mainly to personnel activity. Attempts to reduce noise should concentrate on controlling sounds produced by in-room activities and experimenter traffic; this may reduce the variability of research outcomes and improve animal welfare. PMID:19384312

  2. Role of housing modalities on management and surveillance strategies for adventitious agents of rodents.

    PubMed

    Shek, William R

    2008-01-01

    Specific pathogen-free (SPF) rodents for modern biomedical research need to be free of pathogens and other infectious agents that may not produce disease but nevertheless cause research interference. To meet this need, rodents have been rederived to eliminate adventitious agents and then housed in room- to cage-level barrier systems to exclude microbial contaminants. Because barriers can and do fail, routine health monitoring (HM) is necessary to verify the SPF status of colonies. Testing without strict adherence to biosecurity practices, however, can lead to the inadvertent transfer of unrecognized, inapparent agents among institutions and colonies. Microisolation caging systems have become popular for housing SPF rodents because they are versatile and provide a highly effective cage-level barrier to the entry and spread of adventitious agents. But when a microisolation-caged colony is contaminated, the cage-level barrier impedes the spread of infection and so the prevalence of infection is often low, which increases the chance of missing a contamination and complicates the corroboration of unexpected positive findings. The expanding production of genetically engineered mutant (GEM) rodent strains at research institutions, where biosecurity practices vary and the risk of microbial contamination can be high, underscores the importance of accurate HM results in mitigating the risk of the introduction and spread of microbial contaminants with the exchange of mutant rodent strains among investigators and institutions.

  3. Particulate matter in animal rooms housing mice in microisolation caging.

    PubMed

    Langham, Gregory L; Hoyt, Robert F; Johnson, Thomas E

    2006-11-01

    Reactions to allergens created by laboratory animals are among the most frequently encountered occupational illnesses associated with research animals. Personnel are exposed to these allergens through airborne particulate matter. Although the use of microisolation caging systems can reduce particulate matter concentrations in rooms housing mice, the operating parameters of ventilated caging systems vary extensively. We compared room air in mouse rooms containing 5 different types of caging: 1) individually ventilated caging under positive pressure with filtered intake air and exhaust air returned to the room (VCR+), 2) individually ventilated caging under negative pressure with exhaust air returned to the room (VCR-), 3) individually ventilated caging under positive pressure with exhaust air returned to the heating, ventilation, and air-conditioning (HVAC) system, 4) individually ventilated caging under negative pressure with exhaust air returned to the HVAC system, and 5) static microisolation cages. We found that rooms under VCR conditions had fewer large particles than did those under other conditions, but the numbers of 0.3 microm particles did not differ significantly among systems. Static, positive or negative pressure applied to caging units as well as route of air exhaust were found to have little influence on the total number of particles in the atmosphere. Therefore, considering the heat load, odor, and overall particulate concentration in the room, placing individually ventilated caging under negative pressure with exhaust air returned to the HVAC system appears to be the optimal overall choice when using microisolation housing for rodents.

  4. The relationship between housing conditions and health status of rooming house residents in Toronto.

    PubMed

    Hwang, Stephen W; Martin, Rochelle E; Tolomiczenko, George S; Hulchanski, J David

    2003-01-01

    Rooming houses are an important source of housing for low-income Canadians. Little information is available on the relationship between housing conditions and health status in this vulnerable population. Interviews were conducted with a representative sample of 295 residents in 171 rooming houses in Toronto. Health status was assessed using the SF-36. The physical attractiveness of each rooming house was rated using the Multiphasic Environmental Assessment Procedure. Associations between the health status of residents and the physical attractiveness and organizational characteristics of rooming houses were examined. Rooming house residents aged 35 years and older had significantly poorer health status than their counterparts in the Canadian general population. Eight of the ten dimensions of individual health status assessed by the SF-36 were significantly correlated with the physical attractiveness of the rooming house in which the individual lived. However, there was no significant association between residents' health status and the rooming house's non-profit status, provision of meals, or the presence of an on-site landlord. Rooming house residents suffer from a high prevalence of ill health. Residents reporting worst health are concentrated in rooming houses in the poorest physical condition. This relationship may be mediated by selection processes that place the sickest individuals in the lowest-quality rooming houses, and/or by a direct effect of adverse housing conditions on health status. Further research is needed to elucidate these processes and to improve the health of this vulnerable population.

  5. Housing and testing in mixed-sex rooms increases motivation and accuracy during operant testing in both male and female mice.

    PubMed

    Lloyd, Kelsey R; Yaghoubi, Sarah K; Makinson, Ryan A; McKee, Sarah E; Reyes, Teresa M

    2018-04-01

    Operant behavior tasks are widely used in neuroscience research, but little is known about how variables such as housing and testing conditions affect rodent operant performance. We have previously observed differences in operant performance in male and female mice depending on whether mice were housed and tested in rooms containing only one sex versus rooms containing both sexes. Here, male and female mice in either single-sex or mixed sex housing rooms were trained on fixed ratio 1 (FR1) and progressive ratio (PR) tasks. For both sexes, animals in the mixed sex room had more accurate performance in FR1 and were more motivated in the PR task. We then moved the single sex housed animals to the mixed sex room and vice versa. Animals that started in mixed sex housing had no change to PR, but both sexes who started in single sex housing were more motivated after the switch. Additionally, the females that moved into single-sex housing performed less accurately in FR1. We conclude that housing and testing conditions can affect performance on FR1 and PR tasks. As these tasks are commonly used as training steps to more complex tasks, housing and testing conditions should be carefully considered during experiment design and reported in publications. Copyright © 2018 Elsevier Inc. All rights reserved.

  6. Association of Housing Disrepair Indicators with Cockroach and Rodent Infestations in a Cohort of Pregnant Latina Women and Their Children

    PubMed Central

    Bradman, Asa; Chevrier, Jonathan; Tager, Ira; Lipsett, Michael; Sedgwick, Jaqueline; Macher, Janet; Vargas, Ana B.; Cabrera, Elvia B.; Camacho, Jose M.; Weldon, Rosana; Kogut, Katherine; Jewell, Nicholas P.; Eskenazi, Brenda

    2005-01-01

    Health burdens associated with poor housing and indoor pest infestations are likely to affect young children in particular, who spend most of their time indoors at home. We completed environmental assessments in 644 homes of pregnant Latina women and their children living in the Salinas Valley, California. High residential densities were common, with 39% of homes housing > 1.5 persons per room. Housing disrepair was also common: 58% of homes had peeling paint, 43% had mold, 25% had water damage, and 11% had rotting wood. Evidence of cockroaches and rodents was present in 60% and 32% of homes, respectively. Compared with representative national survey data from the U.S. Department of Housing and Urban Development, homes in our sample were more likely to have rodents, peeling paint, leaks under sinks, and much higher residential densities. The odds of rodent infestations in homes increased in the presence of peeling paint [odds ratio (OR) 2.1; 95% confidence interval (CI), 1.5–3.1], water damage (OR 1.9; 95% CI, 1.2–2.7), and mold (OR 1.5; 95% CI, 1.0–2.1). The odds of cockroach infestation increased in the presence of peeling paint (OR 3.8; 95% CI, 2.7–5.6), water damage (OR 1.9; 95% CI, 1.2–2.9), or high residential density (OR 2.1; 95% CI, 1.2–3.8). Homes that were less clean than average were more prone to both types of infestations. Pesticides were stored or used in 51% of households, partly to control roach and rodent infestations. These data indicate that adverse housing conditions are common in this community and increase the likelihood of pest infestations and home pesticide use. Interventions to improve housing and promote children’s health and safety in this population are needed. PMID:16330367

  7. TENANT HOUSE INTERIOR, LIVING ROOM, NORTH AND EAST WALLS, LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    TENANT HOUSE INTERIOR, LIVING ROOM, NORTH AND EAST WALLS, LOOKING NORTH FROM CENTER OF ROOM - Irvine Ranch Agricultural Headquarters, Carillo Tenant House, Southwest of Intersection of San Diego & Santa Ana Freeways, Irvine, Orange County, CA

  8. TENANT HOUSE INTERIOR, LIVING ROOM, SOUTH AND EAST WALLS, LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    TENANT HOUSE INTERIOR, LIVING ROOM, SOUTH AND EAST WALLS, LOOKING SOUTHEAST FROM CENTER OF ROOM - Irvine Ranch Agricultural Headquarters, Carillo Tenant House, Southwest of Intersection of San Diego & Santa Ana Freeways, Irvine, Orange County, CA

  9. 78 FR 21567 - Installation of Radiation Alarms for Rooms Housing Neutron Sources

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-11

    ... [Docket No. PRM-73-15; NRC-2011-0251] Installation of Radiation Alarms for Rooms Housing Neutron Sources... amend its regulations to require the installation of radiation alarms for rooms housing neutron sources... alarms for rooms housing neutron sources. The petitioner stated that the use of alarms can be effective...

  10. 46. Interior view, tender's house, locker room with original matchstick ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    46. Interior view, tender's house, locker room with original matchstick board siding and wooden lockers. VIEW EAST - Chelsea Street Bridge & Draw Tender's House, Spanning Chelsea River, Boston, Suffolk County, MA

  11. TENANT HOUSE INTERIOR, DOOR DETAIL, FRONT ENTRANCE INTO LIVING ROOM, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    TENANT HOUSE INTERIOR, DOOR DETAIL, FRONT ENTRANCE INTO LIVING ROOM, LOOKING NORTH - Irvine Ranch Agricultural Headquarters, Carillo Tenant House, Southwest of Intersection of San Diego & Santa Ana Freeways, Irvine, Orange County, CA

  12. Housing conditions and stimulus females: a robust social discrimination task for studying male rodent social recognition

    PubMed Central

    Macbeth, Abbe H.; Edds, Jennifer Stepp; Young, W. Scott

    2010-01-01

    Social recognition (SR) enables rodents to distinguish between familiar and novel conspecifics, largely through individual odor cues. SR tasks utilize the tendency for a male to sniff and interact with a novel individual more than a familiar individual. Many paradigms have been used to study the roles of the neuropeptides oxytocin and vasopressin in SR. However, inconsistencies in results have arisen within similar mouse strains, and across different paradigms and laboratories, making reliable testing of social recognition difficult. The current protocol details a novel approach that is replicable across investigators and in different strains of mice. We created a protocol that utilizes gonadally intact, singly housed females presented within corrals to group-housed males. Housing females singly prior to testing is particularly important for reliable discrimination. This methodology will be useful for studying short-term social memory in rodents, and may also be applicable for longer-term studies. PMID:19816420

  13. Utility of Recycled Bedding for Laboratory Rodents

    PubMed Central

    Miyamoto, Toru; Li, Zhixia; Kibushi, Tomomi; Okano, Shinya; Yamasaki, Nakamichi; Kasai, Noriyuki

    2009-01-01

    Animal facilities generate a large amount of used bedding containing excrement as medical waste. We developed a recycling system for used bedding that involves soft hydrothermal processing. In this study, we examined the effects of bedding type on growth, hematologic and serum biochemical values, and organ weights of female and male mice reared on either recycled or fresh bedding from 3 to 33 wk of age. Neither growth nor physiology differed between mice housed on recycled bedding compared with fresh bedding. When 14-wk-old mice were bred, litter size and total number of weaned pups showed no significant differences between animals raised on recycled or fresh bedding. Because bedding type influences the environment within cages and animal rooms, we evaluated particulate and ammonia data from cages and animal rooms. Values were significantly lower from cages and rooms that used recycled bedding than from those using fresh bedding, thus indicating that recycled bedding has the potential to improve the environment within both cages and animal rooms. Overall, this study revealed that recycled bedding is an excellent material for use in housing laboratory rodents. Specifically, recycled bedding may reduce medical waste and maintain healthy environments within cages and animal rooms. PMID:19653951

  14. 11. PUMP HOUSE AND WEIGHING ROOM Fish were pumped from ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. PUMP HOUSE AND WEIGHING ROOM Fish were pumped from floating hoppers, to the pump house (on the far right). From there they were either lifted by conveyor belt to the weighing room (top center) and thence to the holding tanks, or were washed through sealers, weighed and then sluiced to holding tanks. The process used depended upon the type and size of fish. The square cement vat (center) was to be a settling tank from which fish oil, reclaimed from the reduction process, was to be pumped into the round metal tank (above the vat). This process however, was never fully utilized before the sardines ran out. - Hovden Cannery, 886 Cannery Row, Monterey, Monterey County, CA

  15. 63. INTERIOR VIEW, DETAIL, HEAD HOUSE, GROUND FLOOR, BARLOW ROOM, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    63. INTERIOR VIEW, DETAIL, HEAD HOUSE, GROUND FLOOR, BARLOW ROOM, CARVED LINOLEUM WALL PANEL FLANKING THE ENTRANCE, LOOKING WEST - Timberline Lodge, Timberline Trail, Government Camp, Clackamas County, OR

  16. 64. INTERIOR VIEW, DETAIL, HEAD HOUSE, GROUND FLOOR, BARLOW ROOM, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    64. INTERIOR VIEW, DETAIL, HEAD HOUSE, GROUND FLOOR, BARLOW ROOM, CARVED LINOLEUM WALL PANEL FLANKING THE ENTRANCE, LOOKING WEST - Timberline Lodge, Timberline Trail, Government Camp, Clackamas County, OR

  17. 8. INTERIOR, DETAIL OF HOUSE COAL CONVEYOR IN LOADING ROOM, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. INTERIOR, DETAIL OF HOUSE COAL CONVEYOR IN LOADING ROOM, USED TO CONVEY COAL TO A STORAGE HOPPER AND MADE AVAILABLE TO NUTTALLBURG RESIDENTS, LOOKING WEST - Nuttallburg Mine Complex, Tipple, North side of New River, 2.7 miles upstream from Fayette Landing, Lookout, Fayette County, WV

  18. 17. INTERIOR VIEW OF HILLMAN FAN HOUSE ENGINE ROOM LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. INTERIOR VIEW OF HILLMAN FAN HOUSE ENGINE ROOM LOOKING EAST The direct-acting 1883 Pittston Engine and Machine Company steam engine was made by George A. Parrish and W. B. Culver of West Pittston, Pennsylvania. - Dorrance Colliery Fan Complex, South side of Susquehanna River at Route 115 & Riechard Street, Wilkes-Barre, Luzerne County, PA

  19. Social housing of non-rodents during cardiovascular recordings in safety pharmacology and toxicology studies.

    PubMed

    Prior, Helen; Bottomley, Anna; Champéroux, Pascal; Cordes, Jason; Delpy, Eric; Dybdal, Noel; Edmunds, Nick; Engwall, Mike; Foley, Mike; Hoffmann, Michael; Kaiser, Robert; Meecham, Ken; Milano, Stéphane; Milne, Aileen; Nelson, Rick; Roche, Brian; Valentin, Jean-Pierre; Ward, Gemma; Chapman, Kathryn

    2016-01-01

    The Safety Pharmacology Society (SPS) and National Centre for the Replacement, Refinement & Reduction of Animals in Research (NC3Rs) conducted a survey and workshop in 2015 to define current industry practices relating to housing of non-rodents during telemetry recordings in safety pharmacology and toxicology studies. The aim was to share experiences, canvas opinion on the study procedures/designs that could be used and explore the barriers to social housing. Thirty-nine sites, either running studies (Sponsors or Contract Research Organisations, CROs) and/or outsourcing work responded to the survey (51% from Europe; 41% from USA). During safety pharmacology studies, 84, 67 and 100% of respondents socially house dogs, minipigs and non-human primates (NHPs) respectively on non-recording days. However, on recording days 20, 20 and 33% of respondents socially house the animals, respectively. The main barriers for social housing were limitations in the recording equipment used, study design and animal temperament/activity. During toxicology studies, 94, 100 and 100% of respondents socially house dogs, minipigs and NHPs respectively on non-recording days. However, on recording days 31, 25 and 50% of respondents socially house the animals, respectively. The main barriers for social housing were risk of damage to and limitations in the recording equipment used, food consumption recording and temperament/activity of the animals. Although the majority of the industry does not yet socially house animals during telemetry recordings in safety pharmacology and toxicology studies, there is support to implement this refinement. Continued discussions, sharing of best practice and data from companies already socially housing, combined with technology improvements and investments in infrastructure are required to maintain the forward momentum of this refinement across the industry. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  20. The role of rodents in avian influenza outbreaks in poultry farms: a review.

    PubMed

    Velkers, Francisca C; Blokhuis, Simon J; Veldhuis Kroeze, Edwin J B; Burt, Sara A

    2017-12-01

    Wild migratory birds are associated with global avian influenza virus (AIV) spread. Although direct contact with wild birds and contaminated fomites is unlikely in modern non-free range poultry farms applying biosecurity measures, AIV outbreaks still occur. This suggests involvement of other intermediate factors for virus transmission between wild birds and poultry. This review describes current evidence of the potential role of rodents in AIV transmission from wild birds to poultry and between poultry houses. Rodents can be abundant around poultry houses, share their habitat with waterfowl and can readily enter poultry houses. Survival of AIV from waterfowl in poultry house surroundings and on the coat of rodents suggests that rodents are likely to act as mechanical vector. AIVs can replicate in rodents without adaptation, resulting in high viral titres in lungs and nasal turbinates, virus presence in nasal washes and saliva, and transmission to naïve contact animals. Therefore, active AIV shedding by infected rodents may play a role in transmission to poultry. Further field and experimental studies are needed to provide evidence for a role of rodents in AIV epidemiology. Making poultry houses rodent-proof and the immediate surroundings unattractive for rodents are recommended as preventive measures against possible AIV introduction.

  1. ADM. Change House (TAN606). Elevations and floor plan. Room Names. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ADM. Change House (TAN-606). Elevations and floor plan. Room Names. Ralph M. Parsons 902-2-ANP-606-A 65. Date: December 1952. Approved by INEEL Classification Office for public release. INEEL index code no. 035-0606-00-693-106733 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  2. 20 CFR 654.415 - Insect and rodent control.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Insect and rodent control. 654.415 Section 654.415 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR SPECIAL... Insect and rodent control. Housing and facilities shall be free of insects, rodents, and other vermin. ...

  3. 20 CFR 654.415 - Insect and rodent control.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Insect and rodent control. 654.415 Section 654.415 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR SPECIAL... Insect and rodent control. Housing and facilities shall be free of insects, rodents, and other vermin. ...

  4. 76 FR 76327 - Installation of Radiation Alarms for Rooms Housing Neutron Sources

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ... NUCLEAR REGULATORY COMMISSION 10 CFR Part 73 [Docket Nos. PRM-73-15; NRC-2011-0251] Installation of Radiation Alarms for Rooms Housing Neutron Sources AGENCY: Nuclear Regulatory Commission. ACTION: Petition for rulemaking; request for comment. SUMMARY: The U.S. Nuclear Regulatory Commission (NRC or the...

  5. 89. Photocopied August 1978. POWER HOUSE, GENERATOR ROOM, VIEW LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    89. Photocopied August 1978. POWER HOUSE, GENERATOR ROOM, VIEW LOOKING EAST FROM ABOUT THE CENTER, FEBRUARY 26, 1918, AFTER MICHIGAN NORTHERN HAD BROUGHT THE GENERATOR INSTALLATION UP TO FULL CAPACITY. THE NARROW PANEL WESTINGHOUSE SWITCHBOARD INSTALLED IN 1916-17 IS AT THE UPPER RIGHT. THE NEW GENERAL ELECTRIC GENERATORS ARE BELOW THE GALLERY. NOTE THE D.C. EXCITER UNIT ON EXTENDED SHAFT ON THE UNIT IN THE FOREGROUND. A SIMILAR TYPE OF INSTALLATION WAS FOUND AT PENSTOCKS 45 THROUGH 48 AND 62 THROUGH 73. WHAT SEEM TO BE EXTENDED SHAFT UNITS IN THE BACKGROUND ARE MERELY THE OLD STANLEY ALTERNATORS BEFORE THEY HAD BEEN REMOVED FROM THE GENERATOR ROOM. (878) - Michigan Lake Superior Power Company, Portage Street, Sault Ste. Marie, Chippewa County, MI

  6. Movement Patterns of Small Rodents in Lassa Fever-Endemic Villages in Guinea.

    PubMed

    Mariën, Joachim; Kourouma, Fodé; Magassouba, N'Faly; Leirs, Herwig; Fichet-Calvet, Elisabeth

    2018-03-23

    The Natal multimammate mouse (Mastomys natalensis) is the reservoir host of Lassa arenavirus, the etiological agent of Lassa fever in humans. Because there exists no vaccine for human use, rodent control and adjusting human behavior are currently considered to be the only options for Lassa fever control. In order to develop efficient rodent control programs, more information about the host's ecology is needed. In this study, we investigated the spatial behavior of M. natalensis and other small rodents in two capture-mark-recapture and four dyed bait (Rhodamine B) experiments in Lassa fever-endemic villages in Upper Guinea. During the capture-mark-recapture studies, 23% of the recaptured M. natalensis moved between the houses and proximate fields. While M. natalensis was found over the entire study grid (2 ha), other rodent species (Praomys daltoni, Praomys rostratus, Lemniscomys striatus, Mus spp.) were mostly trapped in the surrounding fields. Distances between recapture occasions never exceeded 100 m for all rodent species. During the dyed bait experiments, 11% of M. natalensis and 41% of P. daltoni moved from the fields to houses. We conclude that commensal M. natalensis easily moves between houses and proximate fields in Guinea. We therefore consider occasional domestic rodent elimination to be an unsustainable approach to reduce Lassa virus transmission risk to humans, as M. natalensis is likely to reinvade houses quickly from fields in which rodents are not controlled. A combination of permanent rodent elimination with other control strategies (e.g., make houses rodent proof or attract predators) could be more effective for Lassa fever control, but must be further investigated.

  7. 18. INTERIOR VIEW OF BALTIMORE FAN HOUSE ENGINE ROOM LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. INTERIOR VIEW OF BALTIMORE FAN HOUSE ENGINE ROOM LOOKING EAST The flywheel of the 1908 Allis-Chalmers Corliss steam engine and flywheel are in the foreground. The engine is a horizontal slide valve type with a 24 inch bore and 48 inch stroke. It was direct connected to the Dickson Guibal fan which rotated at 69 revolutions per minute. - Dorrance Colliery Fan Complex, South side of Susquehanna River at Route 115 & Riechard Street, Wilkes-Barre, Luzerne County, PA

  8. 16. INTERIOR VIEW OF HILLMAN FAN HOUSE ENGINE ROOM LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. INTERIOR VIEW OF HILLMAN FAN HOUSE ENGINE ROOM LOOKING EAST This overview of the 1883 Pittston Engine and Machine Company steam engine includes the flywheel and pillowblock in the foreground, with the shaft and cylinder in the background. The engine is a horizontal, slide valve type of 30 inch bore and 60 inch stroke that turned the fan at 49 revolutions per minute. - Dorrance Colliery Fan Complex, South side of Susquehanna River at Route 115 & Riechard Street, Wilkes-Barre, Luzerne County, PA

  9. Translating Research from Animal Models: Does It Matter that Our Rodents are So Cold?

    EPA Science Inventory

    Does it matter that preclinical rodent models are routinely housed below their thermoneutral zone and are thereby cold-stressed? We compile evidence showing that rodents housed below their thermoneutral zone are cold-stressed, hypermetalbolic, hypertensive, sleep-deprived, obesi...

  10. VIEW OF DINING ROOM DOORWAY, FIRST FLOOR HALL, LIVING ROOM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF DINING ROOM DOORWAY, FIRST FLOOR HALL, LIVING ROOM DOORWAY, AND FIREPLACE OF PAULINE KILKER HOUSE, FACING EAST. - Pauline Kilker House, 1410 North Lincoln Avenue-3300 West Laurel Street, Tampa, Hillsborough County, FL

  11. Persistence and clearance of different Salmonella serovars in buildings housing laying hens.

    PubMed

    Carrique-Mas, J J; Breslin, M; Snow, L; McLaren, I; Sayers, A R; Davies, R H

    2009-06-01

    We investigated factors associated with persistence of different Salmonella serovars in buildings housing laying hens in Great Britain using survival analysis. A total of 264 incidents of Salmonella detection occurring between July 1998 and August 2007 in 152 houses were recorded. For incidents involving Salmonella Enteritidis (SE), both the rodent score of the house and the type of house were positively associated with persistence. For non-SE serovars, only the type of house was associated with persistence. Persistence of SE in the houses was longest (>15 months) in step-cage and cage-scraper houses when high levels of rodents were present, and lowest in non-cage and cage-belt houses. We estimated that 42% (95% CI 23.3-63.1) of SE incidents may be cleared during the lay period, and this was related to elimination of rodents from the houses. From January 2009, EU legislation will ban the sale of fresh eggs from SE-positive and S. Typhimurium-positive flocks over their remaining lifespan. If infection is eliminated from such flocks, they would cease to represent a public health risk.

  12. Mortality among residents of shelters, rooming houses, and hotels in Canada: 11 year follow-up study.

    PubMed

    Hwang, Stephen W; Wilkins, Russell; Tjepkema, Michael; O'Campo, Patricia J; Dunn, James R

    2009-10-26

    To examine mortality in a representative nationwide sample of homeless and marginally housed people living in shelters, rooming houses, and hotels. Follow-up study. Canada 1991-2001. 15 100 homeless and marginally housed people enumerated in 1991 census. Age specific and age standardised mortality rates, remaining life expectancies at age 25, and probabilities of survival from age 25 to 75. Data were compared with data from the poorest and richest income fifths as well as with data for the entire cohort Of the homeless and marginally housed people, 3280 died. Mortality rates among these people were substantially higher than rates in the poorest income fifth, with the highest rate ratios seen at younger ages. Among those who were homeless or marginally housed, the probability of survival to age 75 was 32% (95% confidence interval 30% to 34%) in men and 60% (56% to 63%) in women. Remaining life expectancy at age 25 was 42 years (42 to 43) and 52 years (50 to 53), respectively. Compared with the entire cohort, mortality rate ratios for men and women, respectively, were 11.5 (8.8 to 15.0) and 9.2 (5.5 to 15.2) for drug related deaths, 6.4 (5.3 to 7.7) and 8.2 (5.0 to 13.4) for alcohol related deaths, 4.8 (3.9 to 5.9) and 3.8 (2.7 to 5.4) for mental disorders, and 2.3 (1.8 to 3.1) and 5.6 (3.2 to 9.6) for suicide. For both sexes, the largest differences in mortality rates were for smoking related diseases, ischaemic heart disease, and respiratory diseases. Living in shelters, rooming houses, and hotels is associated with much higher mortality than expected on the basis of low income alone. Reducing the excessively high rates of premature mortality in this population would require interventions to address deaths related to smoking, alcohol, and drugs, and mental disorders and suicide, among other causes.

  13. Mortality among residents of shelters, rooming houses, and hotels in Canada: 11 year follow-up study

    PubMed Central

    Wilkins, Russell; Tjepkema, Michael; O’Campo, Patricia J; Dunn, James R

    2009-01-01

    Objective To examine mortality in a representative nationwide sample of homeless and marginally housed people living in shelters, rooming houses, and hotels. Design Follow-up study. Setting Canada 1991-2001. Participants 15 100 homeless and marginally housed people enumerated in 1991 census. Main outcome measures Age specific and age standardised mortality rates, remaining life expectancies at age 25, and probabilities of survival from age 25 to 75. Data were compared with data from the poorest and richest income fifths as well as with data for the entire cohort Results Of the homeless and marginally housed people, 3280 died. Mortality rates among these people were substantially higher than rates in the poorest income fifth, with the highest rate ratios seen at younger ages. Among those who were homeless or marginally housed, the probability of survival to age 75 was 32% (95% confidence interval 30% to 34%) in men and 60% (56% to 63%) in women. Remaining life expectancy at age 25 was 42 years (42 to 43) and 52 years (50 to 53), respectively. Compared with the entire cohort, mortality rate ratios for men and women, respectively, were 11.5 (8.8 to 15.0) and 9.2 (5.5 to 15.2) for drug related deaths, 6.4 (5.3 to 7.7) and 8.2 (5.0 to 13.4) for alcohol related deaths, 4.8 (3.9 to 5.9) and 3.8 (2.7 to 5.4) for mental disorders, and 2.3 (1.8 to 3.1) and 5.6 (3.2 to 9.6) for suicide. For both sexes, the largest differences in mortality rates were for smoking related diseases, ischaemic heart disease, and respiratory diseases. Conclusions Living in shelters, rooming houses, and hotels is associated with much higher mortality than expected on the basis of low income alone. Reducing the excessively high rates of premature mortality in this population would require interventions to address deaths related to smoking, alcohol, and drugs, and mental disorders and suicide, among other causes. PMID:19858533

  14. 24 CFR 3285.502 - Expanding rooms.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Expanding rooms. 3285.502 Section 3285.502 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Optional Features § 3285.502 Expanding rooms. The...

  15. Home alone: a systematic review and meta-analysis on the effects of individual housing on body weight, food intake and visceral fat mass in rodents.

    PubMed

    Schipper, L; Harvey, L; van der Beek, E M; van Dijk, G

    2018-05-01

    Rats and mice are widely used to study environmental effects on psychological and metabolic health. Study designs differ widely and are often characterized by varying (social) housing conditions. In itself, housing has a profound influence on physiology and behaviour of rodents, affecting energy balance and sustainable metabolic health. However, evidence for potential long-term consequences of individual versus social housing on body weight and metabolic phenotype is inconsistent. We conducted a systematic literature review and meta-analyses assessing effects of individual versus social housing of rats and mice, living under well-accepted laboratory conditions, on measures of metabolic health, including body weight, food intake and visceral adipose tissue mass. Seventy-one studies were included in this review; 59 were included in the meta-analysis. Whilst housing did not affect body weight, both food intake and visceral adipose tissue mass were significantly higher in individually compared with socially housed animals. A combination of emotional stress and lack of social thermoregulation likely contributed to these effects. Increased awareness of consequences and improved specifications of housing conditions are necessary to accurately evaluate efficacy of drugs, diets or other interventions on metabolic and other health outcomes because housing conditions are rarely considered as possible moderators of reported outcomes. © 2018 World Obesity Federation.

  16. At Home with Mastomys and Rattus: Human-Rodent Interactions and Potential for Primary Transmission of Lassa Virus in Domestic Spaces

    PubMed Central

    Bonwitt, Jesse; Sáez, Almudena Mari; Lamin, Joseph; Ansumana, Rashid; Dawson, Michael; Buanie, Jacob; Lamin, Joyce; Sondufu, Diana; Borchert, Matthias; Sahr, Foday; Fichet-Calvet, Elisabeth; Brown, Hannah

    2017-01-01

    The multimammate mouse (Mastomys natalensis) is the reservoir for Lassa virus (LASV). Zoonotic transmission occurs when humans are directly or indirectly exposed to fluids of the multimammate mouse, such as urine, saliva, and blood. Housing characteristics and domestic organization affect rodent density in and around households and villages, and are likely to be a risk factor for Lassa fever in humans where the reservoir exists. We use semi-structured interviews (N = 51), a quantitative survey (N = 429), direct observations, and a rodent ecology study to provide new insights into how the organization of domestic spaces brings together humans and rodents and creates pathways for infection in rural settlements in Bo District, Sierra Leone. Rodents were frequently reported inside houses (92.4% of respondents), in which we predominantly trapped M. natalensis (57% of trapped rodents) and Rattus rattus (38% of trapped rodents). Building design and materials provide hiding and nesting places for rodents and lead to close proximity with humans. Patterns of contact are both unintentional and intentional and research participants reported high levels of contact with rodents (34.2% of respondents) and rodent fluids (52.8% of respondents). Rodents are also perceived as a serious threat to food security. These results present detailed knowledge about how humans live with and come into contact with rodents, including the LASV reservoir. Our results argue for further collaborative research in housing and environmental modification such as ceiling construction, food storage, and sanitation as prevention against zoonotic LASV transmission. PMID:28167603

  17. Genotyping and subtyping of Giardia and Cryptosporidium isolates from commensal rodents in China.

    PubMed

    Zhao, Z; Wang, R; Zhao, W; Qi, M; Zhao, J; Zhang, L; Li, J; Liu, A

    2015-05-01

    Cryptosporidium and Giardia are two important zoonotic intestinal parasites responsible for diarrhoea in humans and other animals worldwide. Rodents, as reservoirs or carriers of Cryptosporidium and Giardia, are abundant and globally widespread. In the present study, we collected 232 fecal specimens from commensal rodents captured in animal farms and farm neighbourhoods in China. We collected 33 Asian house rats, 168 brown rats and 31 house mice. 6.0% (14/232) and 8.2% (19/232) of these rodents were microscopy-positive for Giardia cysts and Cryptosporidium oocysts, respectively. All 14 Giardia isolates were identified as Giardia duodenalis assemblage G at a minimum of one or maximum of three gene loci (tpi, gdh and bg). By small subunit rRNA (SSU rRNA) gene sequencing, Cryptosporidium parvum (n = 12) and Cryptosporidium muris (n = 7) were identified. The gp60 gene encoding the 60-kDa glycoprotein was successfully amplified and sequenced in nine C. parvum isolates, all of which belonged to the IIdA15G1 subtype. Observation of the same IIdA15G1 subtype in humans (previously) and in rodents (here) suggests that rodents infected with Cryptosporidium have the potential to transmit cryptosporidiosis to humans.

  18. FACILITY 810A, LIVING ROOM WITH DINING ROOM ON RIGHT AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FACILITY 810A, LIVING ROOM WITH DINING ROOM ON RIGHT AND ENTRY PORCH ON LEFT, VIEW FACING SOUTH. - Schofield Barracks Military Reservation, Duplex Housing Type with Corner Entries, Between Hamilton & Tidball Streets near Williston Avenue, Wahiawa, Honolulu County, HI

  19. Group Housing During Hindlimb Unloading to Simulate Weightlessness

    NASA Technical Reports Server (NTRS)

    Tahimic, Candice; Lowe, Moniece; Steczina, Sonette; Torres, Samantha; Terada, Masahiro; Schreurs, Ann-Sofie; Ronca, April; Alwood, Joshua; Globus, Ruth K.

    2017-01-01

    The rodent hindlimb unloading (HU) model was developed in the 1980s to faciliate the study of mechanisms, responses, and treatments for the adverse effects of spaceflight. A number of variations on unloading systems and cage designs have been developed, although most entail individually housing the HU animals. In this study, we performed hindlimb unloading under group housing conditions. Our preliminary results indicate that HU animals that were group housed for 30 days, displayed musculoskeletal decrements associated with disuse, and further, body weights did not differ compared to age-matched controls. In conclusion, group housing of HU mice provides a novel means to simulate weightlessness under conditions that more closely resemble living conditions of Rodent Research Project ISS flight hardware habitats, and minimizes the social stress of isolation, which is consistent with current animal welfare standards (Guide for the Care and Use of Laboratory Animals: Eighth Edition, National Research Council).

  20. 2. ENGINE ROOM AND CHIPPY ENGINE ROOM OF THE DIAMOND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. ENGINE ROOM AND CHIPPY ENGINE ROOM OF THE DIAMOND MINE, LOOKING NORTH. THE MAIN HOIST USED A FLAT CABLE, WHICH WAS SCRAPPED IN THE 1950s. THE ORIGINAL DIXON CABLE STILL EXISTS IN THE CHIPPY HOIST HOUSE. - Butte Mineyards, Diamond Mine, Butte, Silver Bow County, MT

  1. The use of single room occupancy (SRO) housing as a residential alternative for persons with a chronic mental illness.

    PubMed

    Linhorst, D M

    1991-04-01

    The appropriateness of the use of single room occupancy (SRO) housing for persons with a mental illness is examined, along with the financing and management of SROs, and the provision of mental health services to SRO residents. SROs allow residents personal freedom and privacy, and they offer a sense of community that is capable of meeting a variety of needs. Proper management of SROs is essential to their success. Overall, SROs are found to be a viable source of housing and should be considered as one of several alternatives available to persons with a chronic mental illness.

  2. A novel approach to scavenging anesthetic gases in rodent surgery.

    PubMed

    Nesbitt, Jeffrey C; Krageschmidt, Dale A; Blanco, Michael C

    2013-01-01

    Laboratory animal procedures using gas anesthetics may amass elevated waste gas concentrations in operating rooms if controls are not implemented for capturing and removing the vapors. Area sampling using an infrared analyzer indicated isoflurane concentrations likely to exceed occupational exposure guidelines. Our study showed environmental concentrations of oxygen as high as 40% and isoflurane concentrations >100 ppm when no controls or merely passive controls were utilized. These extraneous isoflurane emissions were determined to be originating from the pre-procedural induction process as well as the gas delivery nose cone. A novel waste gas collection cylinder was designed to enclose the gas delivery nose cone and animal head during the administration of anesthetic gases. The vented cylinder utilized a house vacuum to remove the waste anesthetic gases from the surgical field. A commercially available induction chamber designed to be actively and externally exhausted was used to lower concentrations during the induction process. With implementation of local exhaust ventilation controls, waste anesthetic gas concentrations decreased to below recommended occupational exposure levels. In vitro (sham) testing compared favorably to in vivo measurements validating the reduction capability of active ventilation during rodent anesthetic administration. In vivo isoflurane reductions for the induction chamber emissions, the operating room, and the surgeon's breathing zone were 95%, 60%, and 53%, respectively. The same measurements for an in vitro procedure were 98%, 84%, and 87%, respectively.

  3. Effect of interior door position on room-to-room differences in residential pollutant concentrations after short-term releases

    NASA Astrophysics Data System (ADS)

    Ferro, Andrea R.; Klepeis, Neil E.; Ott, Wayne R.; Nazaroff, William W.; Hildemann, Lynn M.; Switzer, Paul

    Residential interior door positions influence the pollutant concentrations that result from short-term indoor sources, such as cigarettes, candles, and incense. To elucidate this influence, we reviewed past studies and conducted new experiments in three residences: a single-story 714 m 3 ranch-style house, a 510 m 3 two-story split-level house, and a 200 m 3 two-story house. During the experiments, we released sulfur hexafluoride or carbon monoxide tracer gas over short periods (≤30 min) and measured concentrations in the source room and at least one other (receptor) room for various interior door opening positions. We found that closing a door between rooms effectively prevented transport of air pollutants, reducing the average concentration in the receptor room relative to the source room by 57-100% over exposure periods of 1-8 h. When intervening doors were partially or fully open, the reduction in average concentrations ranged from 3% to 99%, varying as a function of door opening width and the distance between source and receptor rooms.

  4. Rodent Habitat on ISS: Advances in Capability for Determining Spaceflight Effects on Mammalian Physiology

    NASA Technical Reports Server (NTRS)

    Globus, R. K.; Choi, S.; Gong, C.; Leveson-Gower, D.; Ronca, A.; Taylor, E.; Beegle, J.

    2016-01-01

    Rodent research is a valuable essential tool for advancing biomedical discoveries in life sciences on Earth and in space. The National Research Counsel's Decadal survey (1) emphasized the importance of expanding NASAs life sciences research to perform long duration, rodent experiments on the International Space Station (ISS). To accomplish this objective, new flight hardware, operations, and science capabilities were developed at NASA ARC to support commercial and government-sponsored research. The flight phases of two separate spaceflight missions (Rodent Research-1 and Rodent Research-2) have been completed and new capabilities are in development. The first flight experiments carrying 20 mice were launched on Sept 21, 2014 in an unmanned Dragon Capsule, SpaceX4; Rodent Research-1 was dedicated to achieving both NASA validation and CASIS science objectives, while Rodent Reesearch-2 extended the period on orbit to 60 days. Groundbased control groups (housed in flight hardware or standard cages) were maintained in environmental chambers at Kennedy Space Center. Crewmembers previously trained in animal handling transferred mice from the Transporter into Habitats under simultaneous veterinary supervision by video streaming and were deemed healthy. Health and behavior of all mice on the ISS was monitored by video feed on a daily basis, and post-flight quantitative analyses of behavior were performed. The 10 mice from RR-1 Validation (16wk old, female C57Bl6/J) ambulated freely and actively throughout the Habitat, relying heavily on their forelimbs for locomotion. The first on-orbit dissections of mice were performed successfully, and high quality RNA (RIN values>9) and liver enzyme activities were obtained, validating the quality of sample recovery. Post-flight sample analysis revealed that body weights of FLT animals did not differ from ground controls (GC) housed in the same hardware, or vivarium controls (VIV) housed in standard cages. Organ weights analyzed post

  5. [Characterization of contacts of the population of Guinea with synanthropic rodents as Lassa fever virus carriers].

    PubMed

    Inapogui, A P; Konstantinov, O K; Lapshov, V N; Comara, S K

    2007-01-01

    Questionnaire surveys made in 17 villages from 3 ecological zones of Guinea have provided evidence for the population's contact with synanthropic rodents as Lassa fever virus carriers. Over 100 rodents are quarterly captured in the houses of the traditional type in the villages located in the savanna woodland. Less than 10 specimens are captured at the food warehouses. There are more than 100 rodents in the majority of houses of the traditional type in the villages located in the secondary forest. In the villages of rainy tropical forests, the capture rate is low--10 to 100 rodents. The main rodent capturers are boys and young men (aged 7 to 20 years) who are principal rodent meat eaters; although almost the whole population, particularly in rural areas, consumes this meat in varying degrees. The proportion of captured rats of the genus Mastomys (the carrier of Lassa fever virus) in the town of Kindia is 11%. In the rural area, it is much higher (as high as 94%) in the villages located in the rainy tropical forests. It is estimated that one trapper quarterly catches 0.2 (in the savanna woodland) to 6.9 (in the secondary forests) infected rats, which agrees with the data of a serological survey of Guinea's population. By and large, the majority of the Guinean population may be referred to as a group at risk for Lassa fever due to their permanent contacts with rodents.

  6. Migrant Farmworker Housing Regulation Violations in North Carolina

    PubMed Central

    Arcury, Thomas A.; Weir, Maria; Chen, Haiying; Summers, Phillip; Pelletier, Lori E.; Galván, Leonardo; Bischoff, Werner E.; Mirabelli, Maria C.; Quandt, Sara A.

    2013-01-01

    Background The quality of housing provided to migrant farmworkers is often criticized, but few studies have investigated these housing conditions. This analysis examines housing regulation violations experienced by migrant farmworkers in North Carolina, and the associations of camp characteristics with the presence of housing violations. Methods Data were collected in183 eastern North Carolina migrant farmworker camps in 2010. Housing regulation violations for the domains of camp, sleeping room, bathroom, kitchen, laundry room, and general housing, as well as total violations were assessed using North Carolina Department of Labor standards. Results Violations of housing regulations were common, ranging from 4 to 22 per camp. Housing regulation violations were common in all domains; the mean number of camp violations was 1.6, of sleeping room violations was 3.8, of bathroom violations was 4.5, of kitchen violations was 2.3, of laundry room violations was 1.2, and of general housing violations was 3.1. The mean number of total housing violations was 11.4. Several camp characteristics were consistently associated with the number of violations; camps with workers having H-2A visas, with North Carolina Department of Labor Certificates of Inspection posted, and assessed early in the season had fewer violations. Conclusions These results argue for regulatory changes to improve the quality of housing provided to migrant farmworkers, including stronger regulations and the more vigorous enforcement of existing regulations. PMID:22237961

  7. Prevalence and covariates of food insecurity among residents of single-room occupancy housing in Chicago, IL, USA.

    PubMed

    Bowen, Elizabeth A; Bowen, Sarah K; Barman-Adhikari, Anamika

    2016-04-01

    Emerging evidence suggests that food insecurity is a significant public health concern among people who are homeless or marginally housed. The present study assessed prevalence of food insecurity and its covariates among a group of marginally housed individuals living in single-room occupancy (SRO) dwellings, a population for which there is little extant health or nutrition research. Cross-sectional survey incorporating the Household Food Insecurity Access Scale. Ten private SRO residences in the Uptown neighbourhood of Chicago, IL, USA, 2013. SRO residents over 18 years of age who were able to communicate verbally in English (n 153). Food insecurity was widespread among SRO residents, with 75 % of the sample considered food insecure and 52 % meeting criteria for severe food insecurity. Bivariate analyses indicated that female gender, eating most meals at a soup kitchen, having a mental health condition, problem drinking, having at least one chronic health condition, and diabetes were all significantly associated with food insecurity. In the multivariate ordered logistic regression model, eating most meals at a soup kitchen remained as the only significant correlate of food insecurity (OR=10·13). SRO residents and other marginally housed populations face unique food access challenges. Although targeted assistance in the form of food stamps and congregate meal programmes remains critical, efforts to prevent and address food insecurity among homeless and marginally housed individuals should include policy interventions that recognize poverty as the root cause of food insecurity and aim to increase overall income and improve housing conditions.

  8. Exploring an analytic model of urban housing strata.

    PubMed

    Park, J H

    1992-07-01

    An analytic model of urban housing strata is developed which utilizes housing structure type, housing tenure type, floor size, physical quality, residential area, and number of rooms to calculate a housing deficit for each housing characteristic. The housing norm is subtracted from the actual housing conditions. Each housing deficit value is weighted according to the priority of the 6 variables and then summed as the housing strata score. Negative scores are below the norm and positive ones above. The model is applied to empirical data for Seoul, Korea. The findings were that 66% of the family sample showed negative scores (unsatisfactory housing conditions). Scores range from -22 to =or+ 18. Morris and Winter's "housing adjustment model" is used to explain housing behavior when there is a gap between housing conditions and the norm. Housing behavior is analyzed with multiple regression analysis of housing strata, social strata, and family life stage variables. Findings indicate that the establishment stage in the family life cycle is more likely to be associated with upper housing strata. From the way the model is set up only those in the establishment, childbearing, and child-rearing stage could get a positive deficit housing score. Size of household is not statistically significant, but upper housing strata are reflective of families with 2.5 members. Those with 3-4.5 members may be in the upper middle housing strata. Those with 5 children are in the lower middle housing strata. Housing strata are significantly related to housing structure type, tenure type, and size and number of rooms. The high rise apartment is likely to be in the upper, the row house and multifamily house in the lower housing, and the single detached house is distributed through all 4 strata. Home ownership is highest in the upper strata. The proportion of housing with 18 pyong and 2 rooms is higher in the lower strata, while housing with 19-32 pyong (63-106 sq. ms) and 3 rooms is higher in

  9. One Room Schools in Iowa.

    ERIC Educational Resources Information Center

    Ruth, Amy, Ed.

    1994-01-01

    This issue focuses on one-room school houses in Iowa. At one time, almost 14,000 one-room schools dotted Iowa's rural landscape. Articles explore Native American schools of the past and present, segregation of black students, and Amish schools. An article remembering one-room schools describes the early schools from 1830 to 1858, township schools…

  10. Rodents on pig and chicken farms - a potential threat to human and animal health.

    PubMed

    Backhans, Annette; Fellström, Claes

    2012-01-01

    Rodents can cause major problems through spreading various diseases to animals and humans. The two main species of rodents most commonly found on farms around the world are the house mouse (Mus musculus) and the brown rat (Rattus norvegicus). Both species are omnivorous and can breed year-round under favourable conditions. This review describes the occurrence of pathogens in rodents on specialist pig and chicken farms, which are usually closed units with a high level of bio-security. However, wild rodents may be difficult to exclude completely, even from these sites, and can pose a risk of introducing and spreading pathogens. This article reviews current knowledge regarding rodents as a hazard for spreading disease on farms. Most literature available regards zoonotic pathogens, while the literature regarding pathogens that cause disease in farm animals is more limited.

  11. Interactive Mold House Tour

    EPA Pesticide Factsheets

    Get a quick glimpse of some of the most important ways to protect your home from mold by this interactive tour of the Mold House. Room-by-room, you'll learn about common mold issues and how to address them.

  12. Detection of Ebola Virus RNA through Aerosol Sampling of Animal Biosafety Level 4 Rooms Housing Challenged Nonhuman Primates

    DTIC Science & Technology

    2016-08-02

    301- 619-4768(f). 1 2 3 4 5 6 7 8 Title: Detection of Ebola Virus RNA through Aerosol Sampling of Animal Biosafety Level 9 4...5 6 To whom it may concern, 7 8 My colleagues and I are submitting the attached manuscript, Detection of Ebola Virus 9 RNA through Aerosol...embedded in the texts. This is the first report demonstrating detection of Ebola virus 17 RNA from animal rooms housing infected nonhuman primates and

  13. Inbred or Outbred? Genetic Diversity in Laboratory Rodent Colonies

    PubMed Central

    Brekke, Thomas D.; Steele, Katherine A.; Mulley, John F.

    2017-01-01

    Nonmodel rodents are widely used as subjects for both basic and applied biological research, but the genetic diversity of the study individuals is rarely quantified. University-housed colonies tend to be small and subject to founder effects and genetic drift; so they may be highly inbred or show substantial genetic divergence from other colonies, even those derived from the same source. Disregard for the levels of genetic diversity in an animal colony may result in a failure to replicate results if a different colony is used to repeat an experiment, as different colonies may have fixed alternative variants. Here we use high throughput sequencing to demonstrate genetic divergence in three isolated colonies of Mongolian gerbil (Meriones unguiculatus) even though they were all established recently from the same source. We also show that genetic diversity in allegedly “outbred” colonies of nonmodel rodents (gerbils, hamsters, house mice, deer mice, and rats) varies considerably from nearly no segregating diversity to very high levels of polymorphism. We conclude that genetic divergence in isolated colonies may play an important role in the “replication crisis.” In a more positive light, divergent rodent colonies represent an opportunity to leverage genetically distinct individuals in genetic crossing experiments. In sum, awareness of the genetic diversity of an animal colony is paramount as it allows researchers to properly replicate experiments and also to capitalize on other genetically distinct individuals to explore the genetic basis of a trait. PMID:29242387

  14. The values of culture and architecture typology of Mandailing traditional house

    NASA Astrophysics Data System (ADS)

    Luthan, P. L. A.

    2016-04-01

    Mandailing is one of bataknesse ethnic in North Sumatera which belong to strong to hold the customs and traditions Mandailing culture which reflected in the parts of the traditional houses. However rapidly the construction modern house make possibility the traditional house which enriched with culture value will be extinct.This studyto identify the value of culture and architecture typology of traditional house in Mandailing Natal North Sumatera. A case study using phenomenology method that is recording and serving the phenomenon which found in field as evidence that include existing condition from building. The finding show that 1) religion system or reliance in the front of location election, ornamentation orientation, construction system and room arrangement, 2) kinship system in the front of room organization, room amount and the completeness, 3) live philosophy found in shape and room arrangement which can accomodate all activity, 4) leadership system in the front of ornamentation shape and the meaning, pillar shape, house size vertically, and 5) social system in the front of roof shape, the used of decoration style and room arrangement. Architecture typology of Mandailing house dug from the shape and the construction, room arrangement, and roof shape.

  15. Front view of bldg 30 which houses mission control

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Front view of bldg 30 which houses mission control. A shift change for the 41-D mission is underway. The windowless wing at left houses three floors, including rooms supporting flight control room 1 and 2.

  16. Maintaining and Monitoring the Defined Microbiota Status of Gnotobiotic Rodents.

    PubMed

    Nicklas, Werner; Keubler, Lydia; Bleich, André

    2015-01-01

    Gnotobiotic (germfree, defined colonized) rodents have become powerful tools to advance our understanding of the host-microbiome relationship. However, the maintenance and ultimately the monitoring of gnotobiotic rodents is a critical, labor-intensive, and costly process (e.g., sterility, not absence of specific pathogens, must be demonstrated in germfree animals). Here, we provide information on the housing and maintenance of gnotobiotic animals, elucidate prophylactic measurements to avoid contamination, and make specific recommendations for sampling procedures, sampling frequencies, and test methods. © The Author 2015. Published by Oxford University Press on behalf of the Institute for Laboratory Animal Research. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  17. EXTERIOR PERSPECTIVE OF TOWER HOUSE, LOOKING SOUTHWEST. (The building’s interior ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    EXTERIOR PERSPECTIVE OF TOWER HOUSE, LOOKING SOUTHWEST. (The building’s interior space is divided into three rooms: the workshop, the mill room, and the tank house. In the tower, the original wood tank that fed water to the Harmon house and the milk house still remains.) - Engle Farm, Tank House, 89 South Ebey Road, Coupeville, Island County, WA

  18. 10. LIVING ROOM INTERIOR SHOWING 1 OVER 1 LIGHT, DOUBLEHUNG, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. LIVING ROOM INTERIOR SHOWING 1 OVER 1 LIGHT, DOUBLEHUNG, WOOD-FRAME WINDOWS FLANKING FRONT ENTRANCE DOOR AND SOUTH END DOOR TO ENCLOSED SLEEPING PORCH/STAIR ACCESS TO ATTIC. CEILING AND WALLS IN THIS ROOM AND THROUGHOUT THE HOUSE ARE COVERED WITH ORIGINAL FIBERBOARD. THE FLOOR IN THIS ROOM AND ALL OTHERS EXCEPT THE BATHROOM, KITCHEN AND DINING ROOM ARE HARDWOOD. VIEW TO SOUTHEAST. - Big Creek Hydroelectric System, Big Creek Town, Operator House, Orchard Avenue south of Huntington Lake Road, Big Creek, Fresno County, CA

  19. [Strategies for sustainable management of commensal rodents. Definitions of control objectives at communal level].

    PubMed

    Plenge-Bönig, A; Schmolz, E

    2014-05-01

    The German Act on the Prevention and Control of Infectious Diseases in Man (Infektionsschutzgesetz, IfSG) provides a legal framework for activities and responsibilities concerning communal rodent control. However, actual governance of communal rodent control is relatively heterogeneous, as federal states (Bundesländer) have different or even no regulations for prevention and management of commensal rodent infestations (e.g. brown rats, roof rats and house mice). Control targets and control requirements are rarely precisely defined and often do not go beyond general measures and objectives. Although relevant regulations provide information about agreed preventive measures against rodents, the concept of sustainability is not expressed as such. A centrally managed database-supported municipal rodent control is a key factor for sustainability because it allows a systematic and analytical approach to identify and reduce rodent populations. The definition of control objectives and their establishment in legal decrees is mandatory for the implementation of a sustainable management strategy of rodent populations at a local level. Systematic recording of rodent infestations through municipal-operated monitoring provides the essential data foundation for a targeted rodent management which is already implemented in some German and European cities and nationwide in Denmark. A sustainable rodent management includes a more targeted rodenticide application which in the long-term will lead to an overall reduction of rodenticide use. Thus, the benefits of sustainable rodent management will be a reduction of rodenticide exposure to the environment, prevention of resistance and long-term economical savings.

  20. Mass Airflow Cabinet for Control of Airborne Infection of Laboratory Rodents

    PubMed Central

    McGarrity, Gerard J.; Coriell, Lewis L.

    1973-01-01

    A mass airflow cabinet for handling and housing of laboratory rodents has been developed and tested. The unit consists of a high-efficiency particulate air filter and uniform distribution of air at a vertical velocity of 19 cm per s. Animals are maintained without bedding in mesh-bottomed cages that rest on rollers for rotation inside the cabinet. There is an air barrier of 90 cm per s separating the cabinet air from room air. Sampling for airborne bacteria yielded an average of 0.03 colony-forming units (CFU) per ft3 of air inside the cabinet, whereas 28.8 CFU per ft3 was simultaneously detected outside the cabinet during housekeeping, a reduction of almost three logs. The efficiency of the air barrier was tested by aerosolization of T3 phage. When phage was aerosolized 5 cm outside the cabinet, no phage could be detected 5 cm inside when the fans were operating; with the fans off an average of 1.6 × 104 plaque-forming units (PFU) per ft3 was detected in six tests. Aerosolization of phage inside the cabinet yielded an average of 9 × 10 PFU per ft3 outside; an average of 4.1 × 106 PFU per ft3 were detected with the fans not in operation, a reduction of more than four logs. In-use studies on effectiveness showed that the cabinet significantly reduced the incidence of mice originally titer-free to Reo-3 virus. Hemagglutination inhibition antibodies to Reo-3 were detected in 9/22 (42%) mice housed in a conventionally ventilated animal laboratory while no seroconversion was detected in any of 22 mice housed in the mass air flow cabinet in the same laboratory. Images PMID:4355261

  1. Mass airflow cabinet for control of airborne infection of laboratory rodents.

    PubMed

    McGarrity, G J; Coriell, L L

    1973-08-01

    A mass airflow cabinet for handling and housing of laboratory rodents has been developed and tested. The unit consists of a high-efficiency particulate air filter and uniform distribution of air at a vertical velocity of 19 cm per s. Animals are maintained without bedding in mesh-bottomed cages that rest on rollers for rotation inside the cabinet. There is an air barrier of 90 cm per s separating the cabinet air from room air. Sampling for airborne bacteria yielded an average of 0.03 colony-forming units (CFU) per ft(3) of air inside the cabinet, whereas 28.8 CFU per ft(3) was simultaneously detected outside the cabinet during housekeeping, a reduction of almost three logs. The efficiency of the air barrier was tested by aerosolization of T3 phage. When phage was aerosolized 5 cm outside the cabinet, no phage could be detected 5 cm inside when the fans were operating; with the fans off an average of 1.6 x 10(4) plaque-forming units (PFU) per ft(3) was detected in six tests. Aerosolization of phage inside the cabinet yielded an average of 9 x 10 PFU per ft(3) outside; an average of 4.1 x 10(6) PFU per ft(3) were detected with the fans not in operation, a reduction of more than four logs. In-use studies on effectiveness showed that the cabinet significantly reduced the incidence of mice originally titer-free to Reo-3 virus. Hemagglutination inhibition antibodies to Reo-3 were detected in 9/22 (42%) mice housed in a conventionally ventilated animal laboratory while no seroconversion was detected in any of 22 mice housed in the mass air flow cabinet in the same laboratory.

  2. Student Housing. A Report.

    ERIC Educational Resources Information Center

    Tolmach, Judy

    This publication describes economical ways to provide better housing for students and provides examples of workable solutions to the problem at various colleges and universities. For more economical and better housing, the author recommends (1) humanizing existing dormitories by changing the standard double rooms into suites of bedrooms with a…

  3. Factors Affecting Radon Concentration in Houses

    NASA Astrophysics Data System (ADS)

    Al-Sharif, Abdel-Latif; Abdelrahman, Y. S.

    2001-03-01

    The dangers to the human health upon exposure to radon and its daughter products is the main motivation behind the vast number of studies performed to find the concentration of radon in our living environment, including our houses. The presence of radon and its daughter products in houses are due to various sources including building materials and the soil under the houses. Many factors affect radon concentration in our houses, the elevation above ground level,ventilation, building materials and room usage being among these factors. In our paper, we discuss the effect of elevation above ground level, room usage and ventilation on the Radon concentration in houses. The faculty residences of the Mu'tah University (Jordan) were chosen in our study. Our results showed that the concentration of radon decreases with elevation. Ventilation rate was also found to affect radon concentration, where low concentrations observed for areas with good ventilation.

  4. 24 CFR 982.605 - SRO: Housing quality standards.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false SRO: Housing quality standards. 982... Types Single Room Occupancy (sro) § 982.605 SRO: Housing quality standards. (a) HQS standards for SRO...) (space and security). Since the SRO units will not house children, the housing quality standards in § 982...

  5. Indoor factors associated with concentrations of house dust mite allergen, Der p 1, in a random sample of houses in Norwich, UK.

    PubMed

    Luczynska, C; Sterne, J; Bond, J; Azima, H; Burney, P

    1998-10-01

    Studies of house dust mite allergen concentrations suggest large variations both within and between homes. It is likely that different household characteristics influence allergen levels in different locations within the house. To investigate household characteristics associated with higher concentrations of house dust mite allergen in a random sample of houses. Information on indoor environment was obtained from 158 adults aged 20-44. Dust samples were collected from their living room floor, bedroom floor and mattress. Concentrations of Der p 1, the major allergen from the house dust mite Dermatophagoides pteronyssinus, were measured by monoclonal antibody immunoassay. Associations between mite allergen concentrations and household characteristics were examined using censored-normal regression models. Factors that were related to Der p 1 (P houses. Geometric mean concentrations of Der p 1 were 1.9 microg/g in living room floor dust, 1.7 microg/g in bedroom floor dust and 2.0 microg/g in mattress dust. Approximately 25% of living room floor and mattress, and over 30% of bedroom floor samples had Der p 1 concentrations greater than 10 microg/g. Household characteristics associated with Der p 1 concentrations in both living room and bedroom were floor level, extractor fan in the kitchen, and age of carpet. Living room Der p 1 concentrations were also associated with gas oven/hob, window condensation, open fires, vacuum cleaner type, smokers in the house and age of house. Bedroom Der p 1 concentrations were also associated with use of blankets and wash temperature of bedding. Mattress Der p 1 concentrations were associated with window condensation, concrete bedroom floor and age of mattress. Different household characteristics were associated with high Der p 1 concentrations in different parts of the house. These findings are relevant

  6. White House Science Fair

    NASA Image and Video Library

    2013-04-22

    U.S. President Barack Obama speaks as he hosts the third-ever White House Science Fair in the East Room at the White House in Washington, April 22, 2013. The science fair celebrated student winners of a broad range of science, technology, engineering and math (STEM) competitions from across the country. Photo Credit: (NASA/Bill Ingalls)

  7. EFFECT OF CAGE BEDDING ON TEMPERATURE REGULATION AND METABOLISM OF GROUP-HOUSED FEMALE MICE.

    EPA Science Inventory

    This manuscript examines how methods used to house and study laboratory rodents could affect the variability and quality of toxicological data. The key finding is that there is likely to be more instability in body temperature and metabolism in mice when housed on conventional be...

  8. Nasal Histopathology and Intracage Ammonia Levels in Female Groups and Breeding Mice Housed in Static Isolation Cages

    PubMed Central

    Mexas, Angela M; Brice, Angela K; Caro, Adam C; Hillanbrand, Troy S

    2015-01-01

    Many factors influence ammonia levels in rodent cages, and high intracage ammonia has been associated with specific types of abnormal nasal pathology in mice. The use of autoclaved corncob bedding and the maintenance of low room humidity reduce the accumulation of ammonia in mouse cages. However, there are no engineering standards that define the limits of ammonia exposure for mice housed in static isolation cages. Regulatory guidance indicates that solid bottom cages must be sanitized at least weekly and that cage components in direct contact with animals must be sanitized at least every 2 wk. Common practice is to replace the bottoms and bedding of static isolation cages once weekly. To determine whether changing static isolation cages once weekly is an appropriate performance standard for mice, we prospectively evaluated the relationship between ammonia levels, nasal histopathology, and housing densities in various grouping strategies of mice housed in static isolation cages. Here, we report that the average nasal pathology score per cage and intracage ammonia levels were correlated, but nasal pathology scores did not differ among mice housed in breeding pairs, breeding trios, or female groups. In light of ammonia levels and histopathology scores as performance standards, these results suggest that a weekly cage-change frequency for static isolation cages does not result in adverse effects. Our results provide evidence to support current practices in the use of static isolation cages for housing laboratory mice in modern vivaria. PMID:26424245

  9. Interior of the shipping room with doorway leading to processing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior of the shipping room with doorway leading to processing room. A pass-through window with conveyor allowed the fresh packed oysters to be sent from the processing room into the shipping room. - J.C. Lore Oyster House, 14430 Solomons Island Road, Solomons, Calvert County, MD

  10. White House Science Fair

    NASA Image and Video Library

    2013-04-22

    U.S. President Obama recognizes NASA Administrator Charles Bolden during his remarks at the 3rd Annual White House Science Fair in the East Room of the White House on Monday, April 22, 2013. The science fair celebrated student winners of a broad range of science, technology, engineering and math (STEM) competitions from across the country. Photo Credit: (NASA/Bill Ingalls)

  11. TRACES OF ORIGINAL PARTITIONS AT JUNCTURE OF FRONT ROOM, REAR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    TRACES OF ORIGINAL PARTITIONS AT JUNCTURE OF FRONT ROOM, REAR ROOM AND HALL, SECOND FLOOR. ALSO SHOWS ORIGINAL STUCCO CORNICE OF FRONT AND REAR ROOMS (LEFT) AND HALL (RIGHT) - Kid-Chandler House, 323 Walnut Street, Philadelphia, Philadelphia County, PA

  12. INTERIOR VIEW OF THE LANAI AND FAMILY ROOM FROM THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR VIEW OF THE LANAI AND FAMILY ROOM FROM THE DINING ROOM. SHOWING THE TONGUE-AND-GROOVE WOOD FLOORING IN THE DINING ROOM. VIEW FACING NORTHEAST. - Hickam Field, Officers' Housing Type L, 702 Julian Avenue, Honolulu, Honolulu County, HI

  13. Urban landscape features influencing rodent control and animal movement in two urban areas of California

    EPA Science Inventory

    “Pest” control of both native (e.g., gophers) and exotic (e.g., black rats, house mice) species may impact populations of non-target species inadvertently. We evaluated relationships among animal movement, rodent control, and landscape features in two urban locations in Californ...

  14. Landscape features influencing residential rodent control and animal movement in two urban areas of California

    EPA Science Inventory

    Residential “pest” control of both native (e.g., gophers, rabbits) and exotic (e.g., black and Norway rats, house mice) species may impact populations of non-target species inadvertently. We evaluated relationships among animal movement, rodent control, and landscape features in...

  15. 75 FR 76744 - National Disaster Housing Task Force

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-09

    ...] National Disaster Housing Task Force AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice of Meeting. SUMMARY: The National Disaster Housing Task Force (NDHTF) will meet by teleconference on December...: Mitchell Wyllins, National Disaster Housing Task Force, 500 C Street, SW., (Room 428), Washington, DC 20472...

  16. 8. EXTERIOR VIEW OF BALTIMORE FAN HOUSE LOOKING NORTHEAST The ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. EXTERIOR VIEW OF BALTIMORE FAN HOUSE LOOKING NORTHEAST The engine room and south airway are in the foreground. The brick walls covering the fan housing and brick upshaft chimney are in the background. The engine room, fan housing, and airways are covered with reinforced concrete roofing. In the left foreground is an airlock leading into the airway. - Dorrance Colliery Fan Complex, South side of Susquehanna River at Route 115 & Riechard Street, Wilkes-Barre, Luzerne County, PA

  17. REAR ELEVATION OF HOUSE, SHOWING CARPORT ON FAR RIGHT, DINING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    REAR ELEVATION OF HOUSE, SHOWING CARPORT ON FAR RIGHT, DINING ROOM ON RIGHT, LIVING ROOM ON THE LEFT. VIEW FACING SOUTH - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Three-Bedroom Single-Family Types 8 and 11, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  18. Maripa Hantavirus in French Guiana: Phylogenetic Position and Predicted Spatial Distribution of Rodent Hosts

    PubMed Central

    de Thoisy, Benoît; Matheus, Séverine; Catzeflis, François; Clément, Luc; Barrioz, Sébastien; Guidez, Amandine; Donato, Damien; Cornu, Jean-François; Brunaux, Olivier; Guitet, Stéphane; Lacoste, Vincent; Lavergne, Anne

    2014-01-01

    A molecular screening of wild-caught rodents was conducted in French Guiana, South America to identify hosts of the hantavirus Maripa described in 2008 in a hantavirus pulmonary syndrome (HPS) case. Over a 9-year period, 418 echimyids and murids were captured. Viral RNA was detected in two sigmodontine rodents, Oligoryzomys fulvescens and Zygodontomys brevicauda, trapped close to the house of a second HPS case that occurred in 2009 and an O. fulvescens close to the fourth HPS case identified in 2013. Sequences from the rodents had 96% and 97% nucleotide identity (fragment of S and M segments, respectively) with the sequence of the first human HPS case. Phylogenetic reconstructions based on the complete sequence of the S segment show that Maripa virus is closely related to Rio Mamore hantavirus. Using environmental descriptors of trapping sites, including vegetation, landscape units, rain, and human disturbance, a maximal entropy-based species distribution model allowed for identification of areas of higher predicted occurrence of the two rodents, where emergence risks of Maripa virus are expected to be higher. PMID:24752689

  19. 9. EXTERIOR VIEW OF BALTIMORE FAN HOUSE LOOKING NORTHEAST The ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. EXTERIOR VIEW OF BALTIMORE FAN HOUSE LOOKING NORTHEAST The brick and concrete construction of the engine room, airways, and chimney are evident. The shaft housing and flywheel of the Allis- Chalmers Corliss steam engine are visible through the window of the engine room. - Dorrance Colliery Fan Complex, South side of Susquehanna River at Route 115 & Riechard Street, Wilkes-Barre, Luzerne County, PA

  20. Isolation and characterization of a novel arenavirus harbored by Rodents and Shrews in Zhejiang province, China

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Kun; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou; Lin, Xian-Dan

    2015-02-15

    To determine the biodiversity of arenaviruses in China, we captured and screened rodents and shrews in Wenzhou city, Zhejiang province, a locality where hemorrhagic fever diseases are endemic in humans. Accordingly, arenaviruses were detected in 42 of 351 rodents from eight species, and in 12 of 272 Asian house shrews (Suncus murinus), by RT-PCR targeting the L segment. From these, a single arenavirus was successfully isolated in cell culture. The virion particles exhibited a typical arenavirus morphology under transmission electron microscopy. Comparison of the S and L segment sequences revealed high levels of nucleotide (>32.2% and >39.6%) and amino acidmore » (>28.8% and >43.8%) sequence differences from known arenaviruses, suggesting that it represents a novel arenavirus, which we designated Wenzhou virus (WENV). Phylogenetic analysis revealed that all WENV strains harbored by both rodents and Asian house shrews formed a distinct lineage most closely related to Old World arenaviruses. - Highlights: • A novel arenavirus (Wenzhou virus) was identified in Zhejiang province, China. • The virus is highly circulating in five species of rats and one species of shrews • More efforts are needed to infer whether it is pathogenic to humans or not.« less

  1. 24 CFR 3280.110 - Minimum room dimensions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Minimum room dimensions. The gross floor area required by § 3280.110 (a) and (b) shall have no clear horizontal dimension less than 5 feet except as permitted by § 3280.102(a). [40 FR 58752, Dec. 18, 1975... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Minimum room dimensions. 3280.110...

  2. 24 CFR 3280.110 - Minimum room dimensions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Minimum room dimensions. The gross floor area required by § 3280.110 (a) and (b) shall have no clear horizontal dimension less than 5 feet except as permitted by § 3280.102(a). [40 FR 58752, Dec. 18, 1975... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Minimum room dimensions. 3280.110...

  3. 24 CFR 3280.110 - Minimum room dimensions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 5 2012-04-01 2012-04-01 false Minimum room dimensions. 3280.110... Minimum room dimensions. The gross floor area required by § 3280.110 (a) and (b) shall have no clear horizontal dimension less than 5 feet except as permitted by § 3280.102(a). [40 FR 58752, Dec. 18, 1975...

  4. 24 CFR 3280.110 - Minimum room dimensions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 5 2014-04-01 2014-04-01 false Minimum room dimensions. 3280.110... Minimum room dimensions. The gross floor area required by § 3280.110 (a) and (b) shall have no clear horizontal dimension less than 5 feet except as permitted by § 3280.102(a). [40 FR 58752, Dec. 18, 1975...

  5. 24 CFR 3280.110 - Minimum room dimensions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Minimum room dimensions. 3280.110... Minimum room dimensions. The gross floor area required by § 3280.110 (a) and (b) shall have no clear horizontal dimension less than 5 feet except as permitted by § 3280.102(a). [40 FR 58752, Dec. 18, 1975...

  6. Wild rodents and shrews are natural hosts of Staphylococcus aureus.

    PubMed

    Mrochen, Daniel M; Schulz, Daniel; Fischer, Stefan; Jeske, Kathrin; El Gohary, Heba; Reil, Daniela; Imholt, Christian; Trübe, Patricia; Suchomel, Josef; Tricaud, Emilie; Jacob, Jens; Heroldová, Marta; Bröker, Barbara M; Strommenger, Birgit; Walther, Birgit; Ulrich, Rainer G; Holtfreter, Silva

    2017-09-22

    Laboratory mice are the most commonly used animal model for Staphylococcus aureus infection studies. We have previously shown that laboratory mice from global vendors are frequently colonized with S. aureus. Laboratory mice originate from wild house mice. Hence, we investigated whether wild rodents, including house mice, as well as shrews are naturally colonized with S. aureus and whether S. aureus adapts to the wild animal host. 295 animals of ten different species were caught in different locations over four years (2012-2015) in Germany, France and the Czech Republic. 45 animals were positive for S. aureus (15.3%). Three animals were co-colonized with two different isolates, resulting in 48 S. aureus isolates in total. Positive animals were found in Germany and the Czech Republic in each studied year. The S. aureus isolates belonged to ten different spa types, which grouped into six lineages (clonal complex (CC) 49, CC88, CC130, CC1956, sequence type (ST) 890, ST3033). CC49 isolates were most abundant (17/48, 35.4%), followed by CC1956 (14/48, 29.2%) and ST890 (9/48, 18.8%). The wild animal isolates lacked certain properties that are common among human isolates, e.g., a phage-encoded immune evasion cluster, superantigen genes on mobile genetic elements and antibiotic resistance genes, which suggests long-term adaptation to the wild animal host. One CC130 isolate contained the mecC gene, implying wild rodents might be both reservoir and vector for methicillin-resistant S. aureus. In conclusion, we demonstrated that wild rodents and shrews are naturally colonized with S. aureus, and that those S. aureus isolates show signs of host adaptation. Copyright © 2017 The Authors. Published by Elsevier GmbH.. All rights reserved.

  7. 75 FR 52689 - Multifamily Housing Reform and Affordability Act: Projects Eligible for a Restructuring Plan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-27

    ... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT 24 CFR Part 401 [Docket No. FR-5304-P-01] RIN 2502... Counsel, Department of Housing and Urban Development, 451 7th Street, SW., Room 10276, Washington, DC..., Department of Housing and Urban Development, 451 7th Street, SW., Room 10276, Washington, DC 20410-0500. 2...

  8. Urban resident attitudes toward rodents, rodent control products, and environmental effects

    EPA Science Inventory

    Rodent control in urban areas can result in the inadvertent mortality of non-target species (e.g., bobcats). However, there is little detailed information about rodent control practices of urban residents. Our objective was to evaluate urban rodent control behaviors in two area...

  9. Rodent allergen in Los Angeles inner city homes of children with asthma.

    PubMed

    Berg, Jill; McConnell, Rob; Milam, Joel; Galvan, Judith; Kotlerman, Jenny; Thorne, Peter; Jones, Craig; Ferdman, Ronald; Eggleston, Peyton; Rand, Cynthia; Lewis, Mary Ann; Peters, John; Richardson, Jean

    2008-01-01

    Recent studies have examined the presence of mouse allergen in inner city children with asthma. Researchers have found high levels of rodent allergen in homes sampled in the northeast and midwest United States, but there has been considerable variation between cities, and there have been few studies conducted in western states. We evaluated the frequency of rodent sightings and detectable mouse allergen and the housing conditions associated with these outcomes in inner city homes in Los Angeles. Two hundred and two families of school children, ages 6-16 living in inner city neighborhoods, participated in the study. Families were predominantly Latino (94%), and Spanish speaking (92%). At study entry, parents completed a home assessment questionnaire, and staff conducted a home evaluation and collected kitchen dust, which was analyzed for the presence of mouse allergen. Fifty-one percent of homes had detectable allergen in kitchen dust. All 33 families who reported the presence of rodents had detectable allergen in the home and were also more likely to have increased levels of allergen compared to those who did not report rodents. Unwashed dishes or food crumbs, lack of a working vacuum, and a caretaker report of a smoker in the home were all significantly associated with a greater risk of rodent sightings or detectable allergen (P<0.05). Detached homes were significantly more likely to have detectable allergen. The prevalence of allergen is common enough that it may have public health implications for asthmatic children, and detectable allergen was not routinely identified based on rodent sightings. Many of the predictors of rodent allergen are amenable to low-cost interventions that can be integrated with other measures to reduce exposure to indoor allergens.

  10. Time management in a co-housed social rodent species (Arvicanthis niloticus).

    PubMed

    Castillo-Ruiz, Alexandra; Indic, Premananda; Schwartz, William J

    2018-01-19

    Sociality has beneficial effects on fitness, and timing the activities of animals may be critical. Social cues could influence daily rhythmic activities via direct effects on the circadian clock or on processes that bypass it (masking), but these possibilities remain incompletely addressed. We investigated the effects of social cues on the circadian body temperature (Tb) rhythms in pairs of co-housed and isolated grass rats, Arvicanthis niloticus (a social species), in constant darkness (DD). Cohabitation did not induce synchronization of circadian Tb rhythms. However, socio-sexual history did affect circadian properties: accelerating the clock in sexually experienced males and females in DD and advancing rhythm phase in the females in a light-dark cycle. To address whether synchronization occurs at an ultradian scale, we analyzed Tb and activity rhythms in pairs of co-housed sisters or couples in DD. Regardless of pair type, co-housing doubled the percentage of time individuals were simultaneously active without increasing individual activity levels, suggesting that activity bouts were synchronized by redistribution over 24 h. Together, our laboratory findings show that social cues affect individual "time allocation" budgets via mechanisms at multiple levels of biological organization. We speculate that in natural settings these effects could be adaptive, especially for group-living animals.

  11. INTERIOR VIEW OF LANAI AND LIVING ROOM, LOOKING TOWARD THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR VIEW OF LANAI AND LIVING ROOM, LOOKING TOWARD THE ENTRY HALL. STAIRS UP TO THE DINING ROOM ON THE LEFT. VIEW FACING WEST. - Hickam Field, Officers' Housing Type L, 702 Julian Avenue, Honolulu, Honolulu County, HI

  12. 4. VIEW WEST FROM DOOR OF NORTHERN ROOM OF WEAVING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. VIEW WEST FROM DOOR OF NORTHERN ROOM OF WEAVING HOUSE, SHOWING FIREPLACE AND REMAINS OF COTTON GIN (The gin is thought to have been made locally in the 19th century by William Ellison, a free black carpenter and enterpreneur; see data pages.) - Borough House, Weaving House, State Route 261 & Garners Ferry Road, Stateburg, Sumter County, SC

  13. 5. INTERIOR VIEW OF UPPER LEVEL ROOM OF THE CONTROL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. INTERIOR VIEW OF UPPER LEVEL ROOM OF THE CONTROL HOUSE LOCATED ON THE SOUTH END OF BIG TUJUNGA DAM SHOWING THE CONTROL PANEL. - Big Tujunga Dam, Control House, 809 West Big Tujunga Road, Sunland, Los Angeles County, CA

  14. Interior of main shucking room. The castiron pot belly stove ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior of main shucking room. The cast-iron pot belly stove at center heated the room. Note the concrete tables and shucking stands lining the walls. - J.C. Lore Oyster House, 14430 Solomons Island Road, Solomons, Calvert County, MD

  15. Maripa hantavirus in French Guiana: phylogenetic position and predicted spatial distribution of rodent hosts.

    PubMed

    de Thoisy, Benoît; Matheus, Séverine; Catzeflis, François; Clément, Luc; Barrioz, Sébastien; Guidez, Amandine; Donato, Damien; Cornu, Jean-François; Brunaux, Olivier; Guitet, Stéphane; Lacoste, Vincent; Lavergne, Anne

    2014-06-01

    A molecular screening of wild-caught rodents was conducted in French Guiana, South America to identify hosts of the hantavirus Maripa described in 2008 in a hantavirus pulmonary syndrome (HPS) case. Over a 9-year period, 418 echimyids and murids were captured. Viral RNA was detected in two sigmodontine rodents, Oligoryzomys fulvescens and Zygodontomys brevicauda, trapped close to the house of a second HPS case that occurred in 2009 and an O. fulvescens close to the fourth HPS case identified in 2013. Sequences from the rodents had 96% and 97% nucleotide identity (fragment of S and M segments, respectively) with the sequence of the first human HPS case. Phylogenetic reconstructions based on the complete sequence of the S segment show that Maripa virus is closely related to Rio Mamore hantavirus. Using environmental descriptors of trapping sites, including vegetation, landscape units, rain, and human disturbance, a maximal entropy-based species distribution model allowed for identification of areas of higher predicted occurrence of the two rodents, where emergence risks of Maripa virus are expected to be higher. © The American Society of Tropical Medicine and Hygiene.

  16. FACILITY 713, DINING ROOM CABINET DOORS AND DOORS FROM LIVING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FACILITY 713, DINING ROOM CABINET DOORS AND DOORS FROM LIVING ROOM TO ENTRY PORCH IN RIGHT BACKGROUND, VIEW FACING NORTHWEST. - Schofield Barracks Military Reservation, Central-Entry Single-Family Housing Type, Between Bragg & Grime Streets near Ayres Avenue, Wahiawa, Honolulu County, HI

  17. Experimental evaluation of rodent exclusion methods to reduce hantavirus transmission to residents in a Native American community in New Mexico.

    PubMed

    Hopkins, Andrew S; Whitetail-Eagle, Joe; Corneli, Amy L; Person, Bobbie; Ettestad, Paul J; DiMenna, Mark; Norstog, Jon; Creswell, Jacob; Khan, Ali S; Olson, James G; Cavallaro, Kathleen F; Bryan, Ralph T; Cheek, James E; Begay, Bruce; Hoddenbach, Gerard A; Ksiazek, Thomas G; Mills, James N

    2002-01-01

    We conducted a pilot study to evaluate the efficacy of rodent proofing continuously occupied homes as a method for lowering the risk for hantavirus pulmonary syndrome (HPS) among residents of a Native American community in northwestern New Mexico. Rodent proofing of dwellings was paired with culturally appropriate health education. Seventy homes were randomly assigned to treatment or control categories. Treatment homes were rodent-proofed by sealing openings around foundations, doors, roofs, and pipes and repairing screens and windows. Repairs to each dwelling were limited to $500 US. After repairs were completed, 15-20 snap traps were placed in each treatment and control home and checked approximately every 2 days for an average of 3-4 weeks. During 23,373 trap nights, one house mouse (Mus musculus) was captured in one treatment home, and 20 mice (16 deer mice, Peromyscus maniculatus, two Pinyon mice, Peromyscus truei, and two unidentified mice) were captured in five control homes (one house had 14 captures, two had two captures, and two had one capture). Trap success was 0.01% in treatment homes and 0.15% in controls. Intensity of infestation (mean number of mice captured per infested home) was 1 in treatment homes and 4 in controls. Observations of evidence of infestation (feces, nesting material, gnaw marks, or reports of infestation by occupant) per 100 days of observation were 1.2 in treatment homes and 3.1 in controls. Statistical power of the experiment was limited because it coincided with a period of low rodent abundance (August-November 2000). Nevertheless, these results suggest that inexpensive rodent proofing of occupied rural homes can decrease the frequency and intensity of rodent intrusion, thereby reducing the risk of HPS among rural residents in the southwestern United States.

  18. Housing Modifications for Persons Who Are Blind or Visually Impaired.

    ERIC Educational Resources Information Center

    Cocke, Elizabeth A.

    1992-01-01

    This paper outlines housing modification issues for both the housing consumer with visual impairments and the builder/remodeler, with emphasis on single-family housing. Suggested modifications are listed for the exterior, entrance, elevator, doors, floors, lighting and the electrical system, windows, room layout and shape, kitchen, and stairs and…

  19. 4. View of Clovelley Farm tenant house, back side (east) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. View of Clovelley Farm tenant house, back side (east) area of two room addition. Note dark metal heating oil tank against rear wall and silver maple trees to shade house from south and east. - Clovelley Farm Tenant House, 4958 Paris Road (east side), Paris, Bourbon County, KY

  20. Northwester upstairs room of northwest wing looking southeast through stair ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Northwester upstairs room of northwest wing looking southeast through stair landing and hallway to southeast room. note far floorboard with smoke damage between historic joists; modern joists in stair landing. - Scheetz Farm, House, 7161 Camp Hill Road, Fort Washington, Montgomery County, PA

  1. Shifts in an invasive rodent community favoring black rats (Rattus rattus) following restoration of native forest

    USGS Publications Warehouse

    Shiels, Aaron B.; Medeiros, Arthur C.; von Allmen, Erica I.

    2017-01-01

    One potential, unintended ecological consequence accompanying forest restoration is a shift in invasive animal populations, potentially impacting conservation targets. Eighteen years after initial restoration (ungulate exclusion, invasive plant control, and out planting native species) at a 4 ha site on Maui, Hawai'i, we compared invasive rodent communities in a restored native dry forest and adjacent non-native grassland. Quarterly for 1 year, we trapped rodents on three replicate transects (107 rodent traps) in each habitat type for three consecutive nights. While repeated trapping may have reduced the rat (Black rat, Rattus rattus) population in the forest, it did not appear to reduce the mouse (House mouse, Mus musculus) population in the grassland. In unrestored grassland, mouse captures outnumbered rat captures 220:1, with mice averaging 54.9 indiv./night versus rats averaging 0.25 indiv./night. In contrast, in restored native forest, rat captures outnumbered mouse captures by nearly 5:1, averaging 9.0 indiv./night versus 1.9 indiv./night for mice. Therefore, relatively recent native forest restoration increased Black rat abundance and also increased their total biomass in the restored ecosystem 36-fold while reducing House mouse biomass 35-fold. Such a community shift is worrisome because Black rats pose a much greater threat than do mice to native birds and plants, perhaps especially to large-seeded tree species. Land managers should be aware that forest restoration (i.e. converting grassland to native forest) can invoke shifts in invasive rodent populations, potentially favoring Black rats. Without intervention, this shift may pose risks for intended conservation targets and modify future forest restoration trajectories.

  2. Rodent phylogeny revised: analysis of six nuclear genes from all major rodent clades

    PubMed Central

    Blanga-Kanfi, Shani; Miranda, Hector; Penn, Osnat; Pupko, Tal; DeBry, Ronald W; Huchon, Dorothée

    2009-01-01

    Background Rodentia is the most diverse order of placental mammals, with extant rodent species representing about half of all placental diversity. In spite of many morphological and molecular studies, the family-level relationships among rodents and the location of the rodent root are still debated. Although various datasets have already been analyzed to solve rodent phylogeny at the family level, these are difficult to combine because they involve different taxa and genes. Results We present here the largest protein-coding dataset used to study rodent relationships. It comprises six nuclear genes, 41 rodent species, and eight outgroups. Our phylogenetic reconstructions strongly support the division of Rodentia into three clades: (1) a "squirrel-related clade", (2) a "mouse-related clade", and (3) Ctenohystrica. Almost all evolutionary relationships within these clades are also highly supported. The primary remaining uncertainty is the position of the root. The application of various models and techniques aimed to remove non-phylogenetic signal was unable to solve the basal rodent trifurcation. Conclusion Sequencing and analyzing a large sequence dataset enabled us to resolve most of the evolutionary relationships among Rodentia. Our findings suggest that the uncertainty regarding the position of the rodent root reflects the rapid rodent radiation that occurred in the Paleocene rather than the presence of conflicting phylogenetic and non-phylogenetic signals in the dataset. PMID:19341461

  3. The rodent research animal holding facility as a barrier to environmental contamination

    NASA Technical Reports Server (NTRS)

    Savage, P. D., Jr.; Jahns, G. C.; Dalton, B. P.; Hogan, R. P.; Wray, A. E.

    1989-01-01

    The rodent Research Animal Holding Facility (RAHF), developed by NASA Ames Research Center (ARC) to separately house rodents in a Spacelab, was verified as a barrier to environmental contaminants during a 12-day biocompatibility test. Environmental contaminants considered were solid particulates, microorganisms, ammonia, and typical animal odors. The 12-day test conducted in August 1988 was designed to verify that the rodent RAHF system would adequately support and maintain animal specimens during normal system operations. Additional objectives of this test were to demonstrate that: (1) the system would capture typical particulate debris produced by the animal; (2) microorganisms would be contained; and (3) the passage of animal odors was adequately controlled. In addition, the amount of carbon dioxide exhausted by the RAHF system was to be quantified. Of primary importance during the test was the demonstration that the RAHF would contain particles greater than 150 micrometers. This was verified after analyzing collection plates placed under exhaust air ducts and rodent cages during cage maintenance operations, e.g., waste tray and feeder changeouts. Microbiological testing identified no additional organisms in the test environment that could be traced to the RAHF. Odor containment was demonstrated to be less than barely detectable. Ammonia could not be detected in the exhaust air from the RAHF system. Carbon dioxide levels were verified to be less than 0.35 percent.

  4. The rodent Research Animal Holding Facility as a barrier to environmental contamination

    NASA Technical Reports Server (NTRS)

    Savage, P. D., Jr.; Jahns, G. C.; Dalton, B. P.; Hogan, R. P.; Wray, A. E.

    1989-01-01

    The rodent Research Animal Holding Facility (RAHF), developed by NASA Ames Research Center (ARC) to separately house rodents in a Spacelab, was verified as a barrier to environmental contaminants during a 12-day biocompatibility test. Environmental contaminants considered were solid particulates, microorganisms, ammonia, and typical animal odors. The 12-day test conducted in August 1988 was designed to verify that the rodent RAHF system would adequately support and maintain animal specimens during normal system operations. Additional objectives of this test were to demonstrate that: (1) the system would capture typical particulate debris produced by the animal; (2) microorganisms would be contained; and (3) the passage of animal odors was adequately controlled. In addition, the amount of carbon dioxide exhausted by the RAHF system was to be quantified. Of primary importance during the test was the demonstration that the RAHF would contain particles greater than 150 micrometers. This was verified after analyzing collection plates placed under exhaust air ducts and and rodent cages during cage maintenance operations, e.g., waste tray and feeder changeouts. Microbiological testing identified no additional organisms in the test environment that could be traced to the RAHF. Odor containment was demonstrated to be less than barely detectable. Ammonia could not be detected in the exhaust air from the RAHF system. Carbon dioxide levels were verified to be less than 0.35 percent.

  5. TENANT HOUSE INTERIOR, KITCHEN, NORTH AND EAST WALLS, LOOKING NORTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    TENANT HOUSE INTERIOR, KITCHEN, NORTH AND EAST WALLS, LOOKING NORTHEAST FROM CENTER OF ROOM - Irvine Ranch Agricultural Headquarters, Carillo Tenant House, Southwest of Intersection of San Diego & Santa Ana Freeways, Irvine, Orange County, CA

  6. TENANT HOUSE INTERIOR, KITCHEN, SOUTH AND EAST WALLS, LOOKING SOUTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    TENANT HOUSE INTERIOR, KITCHEN, SOUTH AND EAST WALLS, LOOKING SOUTHEAST FROM CENTER OF ROOM - Irvine Ranch Agricultural Headquarters, Carillo Tenant House, Southwest of Intersection of San Diego & Santa Ana Freeways, Irvine, Orange County, CA

  7. Text Version of the Indoor Air Quality House Tour

    EPA Pesticide Factsheets

    Get a quick glimpse of some of the most important ways to protect the air in your home by touring the Indoor Air Quality (IAQ) House. Room-by-room, you'll learn about the key pollutants and how to address them.

  8. A method for reducing environmental pollution by using essential oils in rodent pest management program.

    PubMed

    Jokić, Goran; Blažić, Tanja; Đurović-Pejčev, Rada; Đorđević, Tijana; Đedović, Suzana; Vukša, Marina

    2017-08-01

    Strong-smelling plant extracts, such as essential oils, have a variety of feeding effects on mammals. Considering current concerns over long-term health issues and environmental effects of chemicals, plant-based products with repellent or antifungal activities may represent good solutions for improvement of rodent pest control programs. The present study was therefore focused on examining the effects of bergamot, lavender, and thyme essential oils as additional bait components on daily intakes of cereal-based baits by wild house mice. Lavender essential oil, containing linalool and linalyl acetate as main components, and thyme essential oil with a prevailing thymol component had no effects on house mice diet. Bergamot essential oil, whose main components were linalool, limonene, and linalyl acetate, showed a repellent effect on house mouse diet.

  9. FACILITY 713, LIVING ROOM SHOWING DIAMONDPANED WINDOWS FLANKING THE FIREPLACE, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FACILITY 713, LIVING ROOM SHOWING DIAMOND-PANED WINDOWS FLANKING THE FIREPLACE, AND LEADED-GLASS WINDOWS IN DINING ROOM IN RIGHT BACKGROUND, VIEW FACING SOUTHEAST. - Schofield Barracks Military Reservation, Central-Entry Single-Family Housing Type, Between Bragg & Grime Streets near Ayres Avenue, Wahiawa, Honolulu County, HI

  10. Interior view of west main room in original tworoom portion. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior view of west main room in original two-room portion. Note muslin ceiling temporarily tacked up by the HABS team to afford clearer view. Camera facing west. - Warner Ranch, Ranch House, San Felipe Road (State Highway S2), Warner Springs, San Diego County, CA

  11. Housing equity for health equity: a rights-based approach to the control of Lassa fever in post-war Sierra Leone.

    PubMed

    Kelly, J Daniel; Barrie, M Bailor; Ross, Rachel A; Temple, Brian A; Moses, Lina M; Bausch, Daniel G

    2013-01-02

    Poor quality housing is an infringement on the rights of all humans to a standard of living adequate for health. Among the many vulnerabilities of those without adequate shelter is the risk of disease spread by rodents and other pests. One such disease is Lassa fever, an acute and sometimes severe viral hemorrhagic illness endemic in West Africa. Lassa virus is maintained in the rodent Mastomys natalensis, commonly known as the "multimammate rat," which frequently invades the domestic environment, putting humans at risk of Lassa fever. The highest reported incidence of Lassa fever in the world is consistently in the Kenema District of Sierra Leone, a region that was at the center of Sierra Leone's civil war in which tens of thousands of lives were lost and hundreds of thousands of dwellings destroyed. Despite the end of the war in 2002, most of Kenema's population still lives in inadequate housing that puts them at risk of rodent invasion and Lassa fever. Furthermore, despite years of health education and village hygiene campaigns, the incidence of Lassa fever in Kenema District appears to be increasing. We focus on Lassa fever as a matter of human rights, proposing a strategy to improve housing quality, and discuss how housing equity has the potential to improve health equity and ultimately economic productivity in Sierra Leone. The manuscript is designed to spur discussion and action towards provision of housing and prevention of disease in one of the world's most vulnerable populations.

  12. FACILITY 89. INTERIOR OF ENTRY AND STAIR, WITH DINING ROOM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FACILITY 89. INTERIOR OF ENTRY AND STAIR, WITH DINING ROOM TO LEFT, AS SEEN FROM LIVING ROOM. VIEW FACING SOUTHEAST. - U.S. Naval Base, Pearl Harbor, Naval Housing Area Makalapa, Junior Officers' Quarters Type K, Makin Place, & Halawa, Makalapa, & Midway Drives, Pearl City, Honolulu County, HI

  13. Front view of bldg 30 which houses mission control

    NASA Image and Video Library

    1984-08-30

    41D-3072 (30 Aug 1984) --- A 41-D shift change is taking place in the Johnson Space Center's Building 30. In its twenty years of operation, the mission control center has been the scene of many such changes. The windowless wing at left houses three floors, including rooms supporting flight control rooms 1 & 2 (formerly called mission operations control rooms 1 & 2).

  14. 6. STEEL DOORS AND PASSAGES IN SOUTH ROOM OF FAN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. STEEL DOORS AND PASSAGES IN SOUTH ROOM OF FAN HOUSE THAT REGULATE FLOW OF AIR - Sublet Mine No. 6, Fan House, North structure, west side of Willow Creek Valley, east of County Road No. 306, 3 miles north of U.S. Highway 189, Kemmerer, Lincoln County, WY

  15. Zoonoses of rabbits and rodents.

    PubMed

    Hill, William Allen; Brown, Julie Paige

    2011-09-01

    Millions of households in the US own rabbits or rodents, including hamsters, guinea pigs, and gerbils. Activities such as hunting and camping also involve human interactions with wild rabbits and rodents. In many environments, feral rabbits and rodents live in close proximity to humans, domesticated animals, and other wildlife. Education of rodent and rabbit owners and individuals with occupational or recreational exposures to these species is paramount to reduce the prevalence of zoonoses associated with rabbit and rodent exposure.

  16. 33. INTERIOR VIEW, DINING ROOM LOCATED AT THE SOUTHEAST CORNER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    33. INTERIOR VIEW, DINING ROOM LOCATED AT THE SOUTHEAST CORNER OF THE HOUSE ON THE FIRST FLOOR, LOOKING TO THE FIREPLACE IN THE EAST WALL (NOTE DOORWAY TO THE MUSIC ROOM ON THE LEFT (NORTH) SIDE OF THE PHOTOGRAPH) - Arlington Place, 331 Cotton Avenue, Southwest, Birmingham, Jefferson County, AL

  17. VIEW LOOKING SOUTHEAST AT BUILDING 121. THE BUILDING HOUSES OFFICES, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW LOOKING SOUTHEAST AT BUILDING 121. THE BUILDING HOUSES OFFICES, THE ROCKY FLATS PLANT CENTRAL ALARM STATION, ALARM CONSOLES, THE ARMORY, THE LOCK AND KEY SECTION, A COMPUTER ROOM, A UTILITY ROOM, AND LOCKER ROOMS WITH SHOWERS. (1/98) - Rocky Flats Plant, Security & Armory, West of Third Street, south of Central Avenue, Golden, Jefferson County, CO

  18. Identification of Novel Rodent Herpesviruses, Including the First Gammaherpesvirus of Mus musculus▿

    PubMed Central

    Ehlers, Bernhard; Küchler, Judit; Yasmum, Nezlisah; Dural, Güzin; Voigt, Sebastian; Schmidt-Chanasit, Jonas; Jäkel, Thomas; Matuschka, Franz-Rainer; Richter, Dania; Essbauer, Sandra; Hughes, David J.; Summers, Candice; Bennett, Malcolm; Stewart, James P.; Ulrich, Rainer G.

    2007-01-01

    Rodent herpesviruses such as murine cytomegalovirus (host, Mus musculus), rat cytomegalovirus (host, Rattus norvegicus), and murine gammaherpesvirus 68 (hosts, Apodemus species) are important tools for the experimental study of human herpesvirus diseases. However, alphaherpesviruses, roseoloviruses, and lymphocryptoviruses, as well as rhadinoviruses, that naturally infect Mus musculus (house mouse) and other Old World mice are unknown. To identify hitherto-unknown rodent-associated herpesviruses, we captured M. musculus, R. norvegicus, and 14 other rodent species in several locations in Germany, the United Kingdom, and Thailand. Samples of trigeminal ganglia, dorsal root ganglia, brains, spleens, and other organs, as well as blood, were analyzed with a degenerate panherpesvirus PCR targeting the DNA polymerase (DPOL) gene. Herpesvirus-positive samples were subjected to a second degenerate PCR targeting the glycoprotein B (gB) gene. The sequences located between the partial DPOL and gB sequences were amplified by long-distance PCR and sequenced, resulting in a contiguous sequence of approximately 3.5 kbp. By DPOL PCR, we detected 17 novel betaherpesviruses and 21 novel gammaherpesviruses but no alphaherpesvirus. Of these 38 novel herpesviruses, 14 were successfully analyzed by the complete bigenic approach. Most importantly, the first gammaherpesvirus of Mus musculus was discovered (Mus musculus rhadinovirus 1 [MmusRHV1]). This virus is a member of a novel group of rodent gammaherpesviruses, which is clearly distinct from murine herpesvirus 68-like rodent gammaherpesviruses. Multigenic phylogenetic analysis, using an 8-kbp locus, revealed that MmusRHV1 diverged from the other gammaherpesviruses soon after the evolutionary separation of Epstein-Barr virus-like lymphocryptoviruses from human herpesvirus 8-like rhadinoviruses and alcelaphine herpesvirus 1-like macaviruses. PMID:17507487

  19. Efficacy of rodenticide baits for the control of three invasive rodent species in Hawaii.

    PubMed

    Pitt, William C; Driscoll, Laura C; Sugihara, Robert T

    2011-04-01

    We tested the efficacy and palatability of nine commercial rodenticide bait formulations on Polynesian rats (Rattus exulans), roof rats (R. rattus), and house mice (Mus musculus). Efficacy varied by rodenticide tested and rodent species. Generally, rodenticides were more effective against mice than for either of the rat species, and mice tended to consume more rodenticide bait than the laboratory chow alternative food. Efficacy was generally highest for the second-generation anticoagulants tested; however, this varied across products and one-first-generation rodenticide had similar effectiveness. Bait acceptance (palatability) also varied both by rodenticide and by rodent species. Acceptance was the lowest for the acute rodenticides. Bait acceptance appeared to substantially affect the efficacy of rodenticides; materials that were not well accepted produced lower mortality rates. Rodenticide products currently registered for use in Hawaii performed less effectively in this study than other available products not yet registered. Although markets for rodent control products for use on islands are limited, there are advantages to having additional products registered for island use in agriculture, conservation, and public health. © US Government 2010

  20. A room of one's own: the SRO and the single elderly.

    PubMed

    Crystal, S; Beck, P

    1992-10-01

    A survey of 485 single-room occupancy housing (SRO) residents in New York City found elderly residents strongly preferred to remain in centrally located neighborhoods where apartment housing was beyond their means; did not wish to share a housing unit; and had little confidence that they could find acceptable housing if they lost their present unit. For many elderly residents, SROs meet needs not easily met by available alternatives. Results suggest the need to maintain this housing option for older persons and replace losses that have accompanied gentrification in many central city areas.

  1. Chronic Co-species Housing Mice and Rats Increased the Competitiveness of Male Mice.

    PubMed

    Liu, Ying-Juan; Li, Lai-Fu; Zhang, Yao-Hua; Guo, Hui-Fen; Xia, Min; Zhang, Meng-Wei; Jing, Xiao-Yuan; Zhang, Jing-Hua; Zhang, Jian-Xu

    2017-03-01

    Rats are predators of mice in nature. Nevertheless, it is a common practice to house mice and rats in a same room in some laboratories. In this study, we investigated the behavioral and physiological responsively of mice in long-term co-species housing conditions. Twenty-four male mice were randomly assigned to their original raising room (control) or a rat room (co-species-housed) for more than 6 weeks. In the open-field and light-dark box tests, the behaviors of the co-species-housed mice and controls were not different. In a 2-choice test of paired urine odors [rabbit urine (as a novel odor) vs. rat urine, cat urine (as a natural predator-scent) vs. rabbit urine, and cat urine vs. rat urine], the co-species-housed mice were more ready to investigate the rat urine odor compared with the controls and may have adapted to it. In an encounter test, the rat-room-exposed mice exhibited increased aggression levels, and their urines were more attractive to females. Correspondingly, the levels of major urinary proteins were increased in the co-species-housed mouse urine, along with some volatile pheromones. The serum testosterone levels were also enhanced in the co-species-housed mice, whereas the corticosterone levels were not different. The norepinephrine, dopamine, and 5-HT levels in the right hippocampus and striatum were not different between the 2. Our findings indicate that chronic co-species housing results in adaptation in male mice; furthermore, it appears that long-term rat-odor stimuli enhance the competitiveness of mice, which suggests that appropriate predator-odor stimuli may be important to the fitness of prey animals. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  2. 17. INTERIOR VIEW OF THE GENERATOR HOUSE, LOOKING NORTHEAST TOWARD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. INTERIOR VIEW OF THE GENERATOR HOUSE, LOOKING NORTH-EAST TOWARD THE ENCLOSED ROOM HOUSING A BACK-FILLED SHAFT. - Tower Hill No. 2 Mine, Approximately 0.47 mile Southwest of intersection of Stone Church Road & Township Route 561, Hibbs, Fayette County, PA

  3. The importance of housing characteristics in determining Der p 1 levels in carpets in New Zealand homes.

    PubMed

    Wickens, K; Mason, K; Fitzharris, P; Siebers, R; Hearfield, M; Cunningham, M; Crane, J

    2001-06-01

    A previous study of homes in Wellington, New Zealand showed that having carpets on floors was the most important determinant of floor Der p 1 levels, but there was much unexplained variability between houses in carpet levels. To determine to what extent housing characteristics might explain this variability in Der p 1 levels between houses. We returned to a selection of houses with carpets and sampled living room dust from 1 square metre for 1 min and from the whole floor at 5 m(2) per min. Der p 1 levels were estimated by double monoclonal antibody ELISA and are expressed as geometric mean microg/g and microg/m(2) (95% confidence intervals). Questionnaires were used to collect information on housing characteristics. Der p 1 levels were significantly higher in the 1 square metre sample (40.0, 31.9-50.2 microg/g; 53.4, 41.4-68.9 microg/m(2)) than in the whole room (25.8, 21.3-31.1 microg/g; 5.3, 3.8-7.4 microg/m(2)). However, results from the different sampling methods were correlated (r = 0.51, P = 0.001 for microg/g and r = 0.58, P = 0.001 for microg/m(2)). After controlling for possible confounders, houses with insulation or a room or garage below the living room had approximately half the Der p 1 concentration (P = 0.05 for both samples) and the amount of Der p 1 per m(2) (P = 0.004 for the 1 square meter sample, P = 0.06 for the whole room sample) than houses without these features. Having more than two children was associated with higher levels of Der p 1 in 1 square meter, significant (P = 0.05) for microg/m(2). Carpet underlay less than 8 mm thick was associated with an almost 3-fold increase in microg/m(2) Der p 1 (P = 0.03) and a 1.6-fold increase in microg/g Der p 1 (P = 0.08) in the whole room sample, when compared with thicker carpet underlays. The presence of insulation is the single most important housing characteristic explaining the between-house variability in Der p 1 levels on carpeted living room floors.

  4. 1. VIEW OF MILL WORKER HOUSE AT 502 ASKEW AVE. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. VIEW OF MILL WORKER HOUSE AT 502 ASKEW AVE. HOUSE IS 1 1/2 STORY, 3 BAY SIDE GABLE WITH REAR KITCHEN ELL AND PORCH EXTENDING FROM FRONT. LOCKWOOD GREENE ENGINEERS BUILT THIS AND 128 OTHER NEW HOUSES FOR NEW ENGLAND SOUTHERN MILLS IN 1923-1924. THE PREEXISTING MILL VILLAGE NEEDED TO BE EXPANDED TO ACCOMODATE WORKERS FOR THEIR NEW STARK MILL IN HOGANSVILLE. THIS HOUSE WAS BUILT WITH INDOOR PLUMBING, AND ELECTRICITY AT A COST OF APPROXIMATELY $430 PER ROOM. - 502 Askew Avenue (House), 502 Askew Avenue, Hogansville, Troup County, GA

  5. The Watcombe housing study: the short-term effect of improving housing conditions on the indoor environment.

    PubMed

    Richardson, George; Barton, Andrew; Basham, Meryl; Foy, Chris; Eick, Susan Ann; Somerville, Margaret

    2006-05-15

    A three-year study (1999-2001) was initiated in the UK to assess the effect of improving housing conditions in 3-4 bedroom, single-family unit, social rented sector houses on the health of the occupants. The houses were randomised into two groups. Phase I houses received extensive upgrading including wet central heating, on demand ventilation, double-glazed doors, cavity wall and roof/loft insulation. An identical intervention for Phase II houses was delayed for one year. As part of this randomised waiting list study, discrete measurements were made of indoor environmental variables in each house, to assess the short-term effects of improving housing conditions on the indoor environment. Variables representative of indoor environmental conditions were measured in the living room, bedroom and outdoors in each of the three years of the study. In 2000, there was a significant difference between the changes from 1999 to 2000 between Phase I (upgraded) and II (not then upgraded) houses for bedroom temperatures (p=0.002). Changes in wall surface dampness and wall dampness in Phase I houses were also significantly different to the change in Phase II houses in 2000 (p=0.001), but by 2001 the Phase I houses had reverted to the same dampness levels they had before upgrading. The housing upgrades increased bedroom temperatures in all houses. Other indoor environmental variables were not affected.

  6. From the house into the ell south looking north, first ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    From the house into the ell south looking north, first room has tin ceiling and crown molding, the window still has a hood but no other detail, plain trim. Exposed beam and fireplace visible in ell. - Samuel P. Grindle House, 13 School Street, Castine, Hancock County, ME

  7. A Review of Applied Aspects of Dealing with Gut Microbiota Impact on Rodent Models.

    PubMed

    Hansen, Axel Kornerup; Krych, Łukasz; Nielsen, Dennis Sandris; Hansen, Camilla Hartmann Friis

    2015-01-01

    The gut microbiota (GM) affects numerous human diseases, as well as rodent models for these. We will review this impact and summarize ways to handle this challenge in animal research. The GM is complex, with the largest fractions being the gram-positive phylum Firmicutes and the gram-negative phylum Bacteroidetes. Other important phyla are the gram-negative phyla Proteobacteria and Verrucomicrobia, and the gram-positive phylum Actinobacteria. GM members influence models for diseases, such as inflammatory bowel diseases, allergies, autoimmunity, cancer, and neuropsychiatric diseases. GM characterization of all individual animals and incorporation of their GM composition in data evaluation may therefore be considered in future protocols. Germfree isolator-housed rodents or rodents made virtually germ free by antibiotic cocktails can be used to study diverse microbial influences on disease expression. Through subsequent inoculation with selected strains or cocktails of microbes, new "defined flora" models can yield valuable knowledge on the impact of the GM, and of specific GM members and their interactions, on important disease phenotypes and mechanisms. Rodent husbandry and microbial quality assurance practices will be important to ensure and confirm appropriate and research relevant GM. © The Author 2015. Published by Oxford University Press on behalf of the Institute for Laboratory Animal Research. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  8. Interior of processing room showing the passthrough window from the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior of processing room showing the pass-through window from the shucking room. Tally board on the wall was used to keep track of the output of each shucker. Skimming table for rinsing the oyster meat is located under the pass-through window. - J.C. Lore Oyster House, 14430 Solomons Island Road, Solomons, Calvert County, MD

  9. LIVING ROOM. NOTE THE WINDOWS IN THE UPPER PORTION OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    LIVING ROOM. NOTE THE WINDOWS IN THE UPPER PORTION OF THE EXTERIOR WALL (LEFT) AND SLIDING DOORS TO THE DINING ROOM. VIEW FACING SOUTHWEST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Four-Bedroom, Single-Family Type 10, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  10. 6. Keeper's house, first floor, detail of woodwork, looking northeast ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Keeper's house, first floor, detail of woodwork, looking northeast from southwest room into northwest room and stair hall - Ram Island Light Station, Ram Island, south of Ocean Point & just north of Fisherman Island, marking south side of Fisherman Island Passage, Ocean Point, Lincoln County, ME

  11. Habitat-specific shaping of proliferation and neuronal differentiation in adult hippocampal neurogenesis of wild rodents

    PubMed Central

    Cavegn, Nicole; van Dijk, R. Maarten; Menges, Dominik; Brettschneider, Helene; Phalanndwa, Mashudu; Chimimba, Christian T.; Isler, Karin; Lipp, Hans-Peter; Slomianka, Lutz; Amrein, Irmgard

    2013-01-01

    Daily life of wild mammals is characterized by a multitude of attractive and aversive stimuli. The hippocampus processes complex polymodal information associated with such stimuli and mediates adequate behavioral responses. How newly generated hippocampal neurons in wild animals contribute to hippocampal function is still a subject of debate. Here, we test the relationship between adult hippocampal neurogenesis (AHN) and habitat types. To this end, we compare wild Muridae species of southern Africa [Namaqua rock mouse (Micaelamys namaquensis), red veld rat (Aethomys chrysophilus), highveld gerbil (Tatera brantsii), and spiny mouse (Acomys spinosissimus)] with data from wild European Muridae [long-tailed wood mice (Apodemus sylvaticus), pygmy field mice (Apodemus microps), yellow-necked wood mice (Apodemus flavicollis), and house mice (Mus musculus domesticus)] from previous studies. The pattern of neurogenesis, expressed in normalized numbers of Ki67- and Doublecortin(DCX)-positive cells to total granule cells (GCs), is similar for the species from a southern African habitat. However, we found low proliferation, but high neuronal differentiation in rodents from the southern African habitat compared to rodents from the European environment. Within the African rodents, we observe additional regulatory and morphological traits in the hippocampus. Namaqua rock mice with previous pregnancies showed lower AHN compared to males and nulliparous females. The phylogenetically closely related species (Namaqua rock mouse and red veld rat) show a CA4, which is not usually observed in murine rodents. The specific features of the southern environment that may be associated with the high number of young neurons in African rodents still remain to be elucidated. This study provides the first evidence that a habitat can shape adult neurogenesis in rodents across phylogenetic groups. PMID:23616743

  12. Gentrification and Homelessness: The Single Room Occupant and the Inner City Revival.

    ERIC Educational Resources Information Center

    Philip, Kasinitz

    1984-01-01

    Discusses how gentrification, described as due to both a shift in middle class values and to government policy, has forced out the single room occupancy hotels, rooming houses, and shelters that serve marginal populations and thus contributed to the growing numbers of homeless people. (CMG)

  13. 1. VIEW OF SUPERINTENDENT'S HOUSE ON ROUTE 29, LOOKING SOUTHWEST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. VIEW OF SUPERINTENDENT'S HOUSE ON ROUTE 29, LOOKING SOUTHWEST. THIS TWO-STORY, HIPPED-ROOF STRUCTURE WITH A CENTRAL HALL AND CHIMNEY WAS CONSTRUCTED FOR THE SUPERINTENDENT OF STARK MILL, NEW ENGLAND SOUTHERN MILLS IN 1923-24. THE MILL ENGINEERS, LOCKWOOD GREENE COMPANY, ALSO DESIGNED AND BUILT THE NEW MILL HOUSING. THIS HOUSE HAS SEVEN ROOMS, BATH, SCREENED OUTSIDE PORCH AND SLEEPING PORCH, AND GARAGE. IT COST APPROXIMATELY $9,000. - Superintendent's House, Southwest corner of Routes 29 & 100, Hogansville, Troup County, GA

  14. Cost-utility analysis of the housing and health intervention for homeless and unstably housed persons living with HIV.

    PubMed

    Holtgrave, David R; Wolitski, Richard J; Pals, Sherri L; Aidala, Angela; Kidder, Daniel P; Vos, David; Royal, Scott; Iruka, Nkemdiri; Briddell, Kate; Stall, Ron; Bendixen, Arturo Valdivia

    2013-06-01

    We present a cost-utility analysis based on data from the Housing and Health (H&H) Study of rental assistance for homeless and unstably housed persons living with HIV in Baltimore, Chicago and Los Angeles. As-treated analyses found favorable associations of housing with HIV viral load, emergency room use, and perceived stress (an outcome that can be quantitatively linked to quality of life). We combined these outcome data with information on intervention costs to estimate the cost-per-quality-adjusted-life-year (QALY) saved. We estimate that the cost-per-QALY-saved by the HIV-related housing services is $62,493. These services compare favorably (in terms of cost-effectiveness) to other well-accepted medical and public health services.

  15. LIVING ROOM WITH HALL TO BEDROOMS AT FAR WALL. NOTE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    LIVING ROOM WITH HALL TO BEDROOMS AT FAR WALL. NOTE FLOOR TO CEILING WINDOWS ON RIGHT AND SLIDING DOORS TO DINING ROOM ON LEFT. VIEW FACING SOUTHWEST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Three-Bedroom Single-Family Type 7, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  16. LIVING ROOM SHOWING THE FOYER IN BACKGROUND, KITCHEN AT RIGHT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    LIVING ROOM SHOWING THE FOYER IN BACKGROUND, KITCHEN AT RIGHT CENTER, AND DINING ROOM AT RIGHT. NOTE THE CANEC PANEL CEILING. VIEW FACING SOUTHWEST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Three-Bedroom Single-Family Types 8 and 11, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  17. Thermal environment in eight low-energy and twelve conventional Finnish houses.

    PubMed

    Kähkönen, Erkki; Salmi, Kari; Holopainen, Rauno; Pasanen, Pertti; Reijula, Kari

    2015-11-01

    We assessed the thermal environment of eight recently built low-energy houses and twelve conventional Finnish houses. We monitored living room, bedroom and outdoor air temperatures and room air relative humidity from June 2012 to September 2013. Perceived thermal environment was evaluated using a questionnaire survey during the heating, cooling and interim seasons. We compared the measured and perceived thermal environments of the low-energy and conventional houses. The mean air temperature was 22.8 °C (21.9-23.8 °C) in the low-energy houses, and 23.3 °C (21.4-26.5 °C) in the conventional houses during the summer (1. June 2013-31. August 2013). In the winter (1. December 2012-28. February 2013), the mean air temperature was 21.3 °C (19.8-22.5 °C) in the low-energy houses, and 21.6 °C (18.1-26.4 °C) in the conventional houses. The variation of the air temperature was less in the low-energy houses than that in the conventional houses. In addition, the occupants were on average slightly more satisfied with the indoor environment in the low-energy houses. However, there was no statistically significant difference between the mean air temperature and relative humidity of the low-energy and conventional houses. Our measurements and surveys showed that a good thermal environment can be achieved in both types of houses. Copyright © 2015 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  18. INTERIOR, NORTH ROOM WITH CENTRAL DOOR TO EXTERIOR; VIEW TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR, NORTH ROOM WITH CENTRAL DOOR TO EXTERIOR; VIEW TO NORTHEAST - Fort Bragg, Noncommissioned Officers' Service Club, Guest House Building, South of Butner Road, Fayetteville, Cumberland County, NC

  19. White House Science Fair Emphasizes Importance of STEM Education

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2014-06-01

    "I have a confession to make," U.S. president Barack Obama told the audience of young inventors and their mentors at a 27 May White House Science Fair ceremony in the East Room of the White House. "When I was growing up, my science fair projects were not as successful as the ones here." Recalling that during one of his experiments, "a bunch of mice escaped in my grandmother's apartment," Obama joked, "These experiments did not take me straight to the White House."

  20. The Insulation of Houses against Noise from Aircraft in Flight.

    ERIC Educational Resources Information Center

    Scholes, W. E.; Parkin, P. H.

    Three groups of traditional houses were insulated against aircraft noise by double glazing and installing sound attenuating ventilator units. For upper floor rooms of two story houses, overall insulations of 35-40 dB were obtainable, providing transmission through the roofs and down flues were also reduced. The noise levels caused by ventilator…

  1. 13. INTERIOR OF LIVING ROOM NO. 1 IN OPPOSITE VIEW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. INTERIOR OF LIVING ROOM NO. 1 IN OPPOSITE VIEW FROM 145-6-A-12 SHOWING TILED HEATER CORNER WITH WING-WALL AND REMNANTS OF ROOM DIVIDER WALL. DOOR TO BEDROOM NO. 3 AND DOOR TO ALTERNATIVE MAIN FRONT ENTRYWAY ARE VISIBLE ABOVE WING-WALL AT LEFT PHOTO CENTER. DOORWAY TO KITCHEN NO. 2 IS VISIBLE AT OPPOSITE CORNER OF THE ROOM AT RIGHT PHOTO CENTER. VIEW TO NORTHWEST. - Bishop Creek Hydroelectric System, Plant 6, Cashbaugh-Kilpatrick House, Bishop Creek, Bishop, Inyo County, CA

  2. 22. INTERIOR, FIRST FLOOR, EAST SECTION, NORTHEAST ROOM, NORTHWEST CORNER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. INTERIOR, FIRST FLOOR, EAST SECTION, NORTHEAST ROOM, NORTHWEST CORNER (NOTE EXPOSED BRICK NOGGING) - Peter Burr House, Vicinity of State Route 9 & Ridge Road, Shenandoah Junction, Jefferson County, WV

  3. Rodent consumption in Khon Kaen Province, Thailand.

    PubMed

    Suwannarong, Kanokwan; Chapman, Robert S

    2014-09-01

    Rodents are important reservoirs of rodent-borne infections worldwide, including Southeast Asia and Northeast Thailand (Isaan), where rodent consumption may be a source of rodent-borne diseases. The behavior of consuming rodents is related to a population's traditions, knowledge, cultural, and household contexts, among other factors. This cross-sectional survey was conducted in Khon Kaen Province, Thailand during November-December 2011. It aimed to elicit information about rodent consumption among residents of this province, and to identify factors associated with rodent consumption there. Multiple logistic regression analysis indicated that male gender, large family size, and use of rainwater as the main source of drinking water were positively associated with reported rodent consumption in this province, while having proper knowledge/attitudes towards animal-borne disease was negatively associated. These results provide evidence-base information for further studies, such as participatory ac- tion research, to further explore how people interact with rodents in different contexts. Further research is also needed to characterize risk of zoonotic diseases in relation to rodent consumption.

  4. 78 FR 25184 - Federal Housing Administration (FHA): Section 232 Healthcare Facility Insurance Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-30

    ... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT 24 CFR Parts 5, 200, 207, and 232 [Docket No. FR-5465... Residential Care Facilities, Office of Healthcare Programs, Office of Housing, Department of Housing and Urban Development, 451 7th Street SW., Room 6264, Washington, DC 20410-8000; telephone number 202-708- 0599 (this is...

  5. NASA's Rodent Research Project: Validation of Capabilities for Conducting Long Duration Experiments in Space

    NASA Technical Reports Server (NTRS)

    Choi, Sungshin Y.; Cole, Nicolas; Reyes, America; Lai, San-Huei; Klotz, Rebecca; Beegle, Janet E.; Wigley, Cecilia L.; Pletcher, David; Globus, Ruth K.

    2015-01-01

    Research using rodents is an essential tool for advancing biomedical research on Earth and in space. Prior rodent experiments on the Shuttle were limited by the short flight duration. The International Space Station (ISS) provides a new platform for conducting rodent experiments under long duration conditions. Rodent Research (RR)-1 was conducted to validate flight hardware, operations, and science capabilities that were developed at the NASA Ames Research Center. Twenty C57BL6J adult female mice were launched on Sept 21, 2014 in a Dragon Capsule (SpaceX-4), then transferred to the ISS for a total time of 21-22 days (10 commercial mice) or 37 days (10 validation mice). Tissues collected on-orbit were either rapidly frozen or preserved in RNAlater at -80C (n2group) until their return to Earth. Remaining carcasses on-orbit were rapidly frozen for dissection post-flight. The three controls groups at Kennedy Space Center consisted of: Basal mice euthanized at the time of launch, Vivarium controls housed in standard cages, and Ground Controls (GC) housed in flight hardware within an environmental chamber. Upon return to Earth, there were no differences in body weights between Flight (FLT) and GC at the end of the 37 days in space. Liver enzyme activity levels of FLT mice and all control mice were similar in magnitude to those of the samples that were processed under optimal conditions in the laboratory. Liver samples dissected on-orbit yielded high quality RNA (RIN8.99+-0.59, n7). Liver samples dissected post-flight from the intact, frozen FLT carcasses yielded RIN of 7.27 +- 0.52 (n6). Additionally, wet weights of various tissues were measured. Adrenal glands and spleen showed no significant differences in FLT compared to GC although thymus and livers weights were significantly greater in FLT compared to GC. Over 3,000 tissue aliquots collected post-flight from the four groups of mice were deposited into the Ames Life Science Data Archives for future Biospecimen

  6. Rodents and Risk in the Mekong Delta of Vietnam: Seroprevalence of Selected Zoonotic Viruses in Rodents and Humans

    PubMed Central

    Van Cuong, Nguyen; Carrique-Mas, Juan; Vo Be, Hien; An, Nguyen Ngoc; Tue, Ngo Tri; Anh, Nguyet Lam; Anh, Pham Hong; Phuc, Nguyen The; Baker, Stephen; Voutilainen, Liina; Jääskeläinen, Anne; Huhtamo, Eili; Utriainen, Mira; Sironen, Tarja; Vaheri, Antti; Henttonen, Heikki; Vapalahti, Olli; Chaval, Yannick

    2015-01-01

    Abstract In the Mekong Delta in southern Vietnam, rats are commonly traded in wet markets and sold live for food consumption. We investigated seroprevalence to selected groups of rodent-borne viruses among human populations with high levels of animal exposure and among co-located rodent populations. The indirect fluorescence antibody test (IFAT) was used to determine seropositivity to representative reference strains of hantaviruses (Dobrava virus [DOBV], Seoul virus [SEOV]), cowpox virus, arenaviruses (lymphocytic choriomeningitis virus [LCMV]), flaviviruses (tick-borne encephalitis virus [TBEV]), and rodent parechoviruses (Ljungan virus), using sera from 245 humans living in Dong Thap Province and 275 rodents representing the five common rodent species sold in wet markets and present in peridomestic and farm settings. Combined seropositivity to DOBV and SEOV among the rodents and humans was 6.9% (19/275) and 3.7% (9/245), respectively; 1.1% (3/275) and 4.5% (11/245) to cowpox virus; 5.4% (15/275) and 47.3% (116/245) for TBEV; and exposure to Ljungan virus was 18.8% (46/245) in humans, but 0% in rodents. Very little seroreactivity was observed to LCMV in either rodents (1/275, 0.4%) or humans (2/245, 0.8%). Molecular screening of rodent liver tissues using consensus primers for flaviviruses did not yield any amplicons, whereas molecular screening of rodent lung tissues for hantavirus yielded one hantavirus sequence (SEOV). In summary, these results indicate low to moderate levels of endemic hantavirus circulation, possible circulation of a flavivirus in rodent reservoirs, and the first available data on human exposures to parechoviruses in Vietnam. Although the current evidence suggests only limited exposure of humans to known rodent-borne diseases, further research is warranted to assess public health implications of the rodent trade. PMID:25629782

  7. INTERIOR VIEW OF LIVING ROOM. NOTE THE OPENING FOR AN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR VIEW OF LIVING ROOM. NOTE THE OPENING FOR AN AIR CONDITIONER ON THE FAR WALL AND THE SLIDING DOORS TO THE DINING ROOM ON THE LEFT. VIEW FACING SOUTHEAST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, U-Shaped Two-Bedroom Single-Family Type 6, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  8. The housing, geography, and mobility of Latin American urban poor: the prevailing model and the case of Quito, Ecuador.

    PubMed

    Klak, T; Holtzclaw, M

    1993-01-01

    In this study of the constraints of low-income migrants in securing decent housing in Quito, Ecuador (a rapidly growing city), there is a literature review of Latin American intraurban mobility and housing, the development of a theoretical model, and a bivariate analysis. John Turner's model of the three stages in the life cycle of migrants and the three concentric zones of urbanization provides the initial framework for examining Quito migration. Quito differs from other Third World and Latin American cities in that its origins are pre-Colombian, and physical barriers surround the city. Data were obtained from housing data collected independently in 1990 and 1991 and survey data on households living in 1000 inadequate housing units in 1989. 35.5% of Quito's population live in inadequate housing (poor building materials, poor construction, deterioration, or lack of basic services). Three concentric and elongated zones are constructed based on distance from the center city and periphery and are representative of shelter types (rented rooms, shanty, house, and apartment). Shelter improves with type of ownership status. The attitudes of local officials influences the proportion of the poor living in rental or self-help housing. 36% of Quito's low-income residents live in rented rooms, and 38% live in shanties and houses. Bridgeheaders (new migrants who are usually young single males) tend to live in rented rooms for under five years and to move over time to shanties and then houses. Colonial preservation in central Quito and landlords' incentives for encouraging migrants to stay in rental housing interferes with the third phase of the model. Mixed housing throughout the city fits the third phase. Local laws prevent squatters and self-help housing. Rented rooms are primarily in the central city. Occupant income increases with shifts from rented rooms, to shanties, to houses. Shelter, geographic, and mobility patterns that do not fit the model are identified. Urban

  9. The study of a space configuration using space syntax analysis Case study: an elderly housing

    NASA Astrophysics Data System (ADS)

    Mariana, Yosica; Triwardhani, Arindra J.; Isnaeni Djimantoro, Michael

    2017-12-01

    The improvement in various aspect leads to prolong the life span of human life, which increasing the number of elderly in the urban areas in return. But the increasing population is not supported by the provision of adequate housing facilities for them. Most of the elderly house in Jakarta, is designed just like for common people without relizing thatthey had physical and mentally degradation following the age. Therefore, the elderly house need to design with special attention to their daily activity mobility which applied in effective room configuration. The connectivity between the activities is most important element to order the room configuration. This research conduct to search the room configuration in elderly house which can improve their productivity and live quality by using the space syntax theory. The research methods by using the syntactic plug-in in Grasshooper software and analyse the integration, choice, control value and entrophy in the activity configuration. The result show that the effective and efficient for elderly house is cluster centralized pattern. The lobby and reception take the important role as the integration aspect and the spatial awareness according to elderly activity.

  10. Environmental Health and Safety Hazards Experienced by Home Health Care Providers: A Room-by-Room Analysis.

    PubMed

    Polivka, Barbara J; Wills, Celia E; Darragh, Amy; Lavender, Steven; Sommerich, Carolyn; Stredney, Donald

    2015-11-01

    The number of personnel providing in-home health care services is increasing substantially. The unique configuration of environmental hazards in individual client homes has a significant impact on the safety and health of home health care providers (HHPs). This mixed-methods study used data from a standardized questionnaire, focus groups, and individual interviews to explore environmental health and safety hazards encountered by HHPs in client homes. The participant sample (N = 68) included nurses, aides, therapists, and owners/managers from a variety of geographic locations. The most often-reported hazards were trip/slip/lift hazards, biohazards, and hazards from poor air quality, allergens, pests and rodents, and fire and burns. Frequency of identified key hazards varied by room, that is, kitchen (e.g., throw rugs, water on floor), bathroom (e.g., tight spaces for client handling), bedroom (e.g., bed too low), living room (e.g., animal waste), and hallway (e.g., clutter). Findings indicate the need for broader training to enable HHPs to identify and address hazards they encounter in client homes. © 2015 The Author(s).

  11. 24. Detail, typical interior door, from living room to master ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. Detail, typical interior door, from living room to master bedroom; view to south; 135mm lens with electronic flash illumination. - Warner Hutton House, 13495 Sousa Lane, Saratoga, Santa Clara County, CA

  12. The effect of house design and environment on fungal movement in homes of bronchial asthma patients.

    PubMed

    Takatori, K; Saito, A; Yasueda, H; Akiyama, K

    2001-01-01

    The effect of house building design and environment on the fungal movement in the houses of 41 bronchial asthma (BA) patients has been investigated by examining house dust. The presence and composition of fungi were determined and compared in relation to building structure, house age, size of living room, main flooring material, presence of a living-room rug or air purifier, and frequency of vacuum cleaning. Among these elements, fungal CFU apparently varied only between building structure: wooden-board houses had significantly higher numbers of fungi than reinforced concrete houses (p < 0.01), and wooden mortar or iron-framed prefabricated houses had significantly higher numbers of fungi than reinforced concrete houses (p < 0.05). Classification of the types of fungi present in the house dust of BA patients showed that, regardless of the building designs, there were high levels of osmophilic fungi (group A) and fungi that survive at relatively dry conditions (group B), whereas fungi that survive in very wet conditions (group D) were present at low frequency.

  13. 21 CFR 1250.96 - Rodent control.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Rodent control. 1250.96 Section 1250.96 Food and... SANITATION Sanitation Facilities and Conditions on Vessels § 1250.96 Rodent control. Vessels shall be... of rodent control. ...

  14. 21 CFR 1250.96 - Rodent control.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Rodent control. 1250.96 Section 1250.96 Food and... SANITATION Sanitation Facilities and Conditions on Vessels § 1250.96 Rodent control. Vessels shall be... of rodent control. ...

  15. 21 CFR 1250.96 - Rodent control.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Rodent control. 1250.96 Section 1250.96 Food and... SANITATION Sanitation Facilities and Conditions on Vessels § 1250.96 Rodent control. Vessels shall be... of rodent control. ...

  16. 21 CFR 1250.96 - Rodent control.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Rodent control. 1250.96 Section 1250.96 Food and... SANITATION Sanitation Facilities and Conditions on Vessels § 1250.96 Rodent control. Vessels shall be... of rodent control. ...

  17. 21 CFR 1250.96 - Rodent control.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Rodent control. 1250.96 Section 1250.96 Food and... SANITATION Sanitation Facilities and Conditions on Vessels § 1250.96 Rodent control. Vessels shall be... of rodent control. ...

  18. FIRST FLOOR REAR ROOM. SECOND FLOOR HAS BEEN REMOVED NOTE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FIRST FLOOR REAR ROOM. SECOND FLOOR HAS BEEN REMOVED-- NOTE PRESENCE OF SECOND FLOOR WINDOWS AT LEFT. See also PA-1436 B-6 - Kid-Physick House, 325 Walnut Street, Philadelphia, Philadelphia County, PA

  19. FIRST FLOOR REAR ROOM. SECOND FLOOR HAS BEEN REMOVED NOTE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FIRST FLOOR REAR ROOM. SECOND FLOOR HAS BEEN REMOVED-- NOTE PRESENCE OF SECOND FLOOR WINDOWS AT LEFT. See also PA-1436 B-13 - Kid-Physick House, 325 Walnut Street, Philadelphia, Philadelphia County, PA

  20. Proceedings of a workshop on Lighting Requirements in Microgravity: Rodents and Nonhuman Primates

    NASA Technical Reports Server (NTRS)

    Holley, Daniel C. (Editor); Winget, Charles M. (Editor); Leon, Henry A. (Editor)

    1988-01-01

    A workshop, sponsored by Ames Research Center, was held at San Jose State University, San Jose, California, July 16-17, 1987, to discuss and correlate observations and theories relating to lighting requirements in animal habitats for rodents and nonhuman primates in microgravity (near space). This volume represents the results of the workshop. It contains a summary of the conclusions reached and recommendations for lighting animal housing modules used in microgravity related projects. The recommendations cover various aspects of habitat lighting including engineering standards for intensity, spectral properties, and light cycle controls.

  1. Aquaporins in desert rodent physiology.

    PubMed

    Pannabecker, Thomas L

    2015-08-01

    Desert rodents face a sizeable challenge in maintaining salt and water homeostasis due to their life in an arid environment. A number of their organ systems exhibit functional characteristics that limit water loss above that which occurs in non-desert species under similar conditions. These systems include renal, pulmonary, gastrointestinal, nasal, and skin epithelia. The desert rodent kidney preserves body water by producing a highly concentrated urine that reaches a maximum osmolality nearly three times that of the common laboratory rat. The precise mechanism by which urine is concentrated in any mammal is unknown. Insights into the process may be more apparent in species that produce highly concentrated urine. Aquaporin water channels play a fundamental role in water transport in several desert rodent organ systems. The role of aquaporins in facilitating highly effective water preservation in desert rodents is only beginning to be explored. The organ systems of desert rodents and their associated AQPs are described. © 2015 Marine Biological Laboratory.

  2. Use of radiometer to reform and repair an old living house to passive solar one

    NASA Astrophysics Data System (ADS)

    Okamoto, Yoshizo; Inagaki, Terumi; Suzuki, Takakazu; Kurokawa, Takashi

    1994-03-01

    Japanese living houses mainly consist of wooden elements in high-temperature and moist conditions. To modify the hot and humid environment, a conventional old house was partially rebuilt and repaired. Especially in the winter season, a diagnostic thermographic test was used to find deteriorated and leaking parts of interior and exterior walls. Macroscopic deteriorated parts were checked again in detail. The deteriorated element was then removed. During the reconstruction process, a new solar heat and air conditioning system using a silica-gel adsorber and underground water was installed to cool and warm up the living room. Thermography tests of this remodeled house show that room temperature is always constant and mild to human beings, especially in the winter. Temperature and heat flow distribution of flowing air in the living room was measured using thermal net and wire methods. Leaking thermal streak flow of the gap was locally visualized by the IR radiometer and a highly sensitive video camera. It was verified that IR thermography is a useful measuring instrument to check thermal defects of a house.

  3. Increased survivorship of testosterone-treated female house mice (Mus musculus) in high-density field conditions

    Treesearch

    W.J. Zielinski; J.G. Vandenbergh

    1991-01-01

    Differences in hormone levels influence sexual differences in aggression. survival, home-range size and dispcrsal in rodents. The role oftestosterone in establishing some of these differences in wild house mice was examined. Females treated with either 0·5 mg of testosterone enanthate (TE-treated) or oil (control), and an...

  4. Supplemental treatment of air in airborne infection isolation rooms using high-throughput in-room air decontamination units.

    PubMed

    Bergeron, Vance; Chalfine, Annie; Misset, Benoît; Moules, Vincent; Laudinet, Nicolas; Carlet, Jean; Lina, Bruno

    2011-05-01

    Evidence has recently emerged indicating that in addition to large airborne droplets, fine aerosol particles can be an important mode of influenza transmission that may have been hitherto underestimated. Furthermore, recent performance studies evaluating airborne infection isolation (AII) rooms designed to house infectious patients have revealed major discrepancies between what is prescribed and what is actually measured. We conducted an experimental study to investigate the use of high-throughput in-room air decontamination units for supplemental protection against airborne contamination in areas that host infectious patients. The study included both intrinsic performance tests of the air-decontamination unit against biological aerosols of particular epidemiologic interest and field tests in a hospital AII room under different ventilation scenarios. The unit tested efficiently eradicated airborne H5N2 influenza and Mycobacterium bovis (a 4- to 5-log single-pass reduction) and, when implemented with a room extractor, reduced the peak contamination levels by a factor of 5, with decontamination rates at least 33% faster than those achieved with the extractor alone. High-throughput in-room air treatment units can provide supplemental control of airborne pathogen levels in patient isolation rooms. Copyright © 2011 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

  5. 5. EAST SECTION OF BUILDING, FIRST FLOOR, WEST ROOM. NOTE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. EAST SECTION OF BUILDING, FIRST FLOOR, WEST ROOM. NOTE OVEN AT LEFT. All construction original except wood flooring, plumbing and electricity. - Ralph Izard House, Kitchen Building, 110 Broad Street, Charleston, Charleston County, SC

  6. 20. Living room, view to east wall and pocket doors ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. Living room, view to east wall and pocket doors to front parlor; view to east; 65mm lens with electronic flash illumination. - Warner Hutton House, 13495 Sousa Lane, Saratoga, Santa Clara County, CA

  7. Behavioral assessment of intermittent wheel running and individual housing in mice in the laboratory.

    PubMed

    Pham, Therese M; Brené, Stefan; Baumans, Vera

    2005-01-01

    Physical cage enrichment--exercise devices for rodents in the laboratory--often includes running wheels. This study compared responses of mice in enriched physical and social conditions and in standard social conditions to wheel running, individual housing, and open-field test. The study divided into 6 groups, 48 female BALB/c mice group housed in enriched and standard conditions. On alternate days, the study exposed 2 groups to individual running wheel cages. It intermittently separated from their cage mates and housed individually 2 groups with no running wheels; 2 control groups remained in enriched or standard condition cages. There were no significant differences between enriched and standard group housed mice in alternate days' wheel running. Over time, enriched, group housed mice ran less. Both groups responded similarly to individual housing. In open-field test, mice exposed to individual housing without running wheel moved more and faster than wheel running and home cage control mice. They have lower body weights than group housed and wheel running mice. Intermittent withdrawal of individual housing affects the animals more than other commodities. Wheel running normalizes some effects of intermittent separation from the enriched, social home cage.

  8. Effects of Cage Type and NASA Rodent Food Bar in Male Sprague-Dawley Rats

    NASA Technical Reports Server (NTRS)

    Lau, Angela; Ramirez, J.; Pruitt, S.; Melson, E.; Zirkle-Yoshida, M.; Girten, B.; Apseloff, G.

    2001-01-01

    Early prototype caging for the rodent Advanced Animal Habitat (P-AAH) for the International Space Station (ISS) is currently being tested. In this five week study, effects of the wire-bottom P-AAH cages and specialized NASA rodent food bars (FB) were compared to standard vivarium cages (VIV) with corn-cob, litter-filled bottoms, and standard Purina rat chow (CH). Ninety-six male Sprague-Dawley rats were divided into four treatment groups (24 rats/treatment): Group 1) VIV+CH, Group 2) P-AAH+CH, Group 3) VIV+FB, and Group 4) P-AAH+FB. Each VIV and P-AAH cage housed three and six rats, respectively. After five weeks of treatment rats were weighed, euthanized, and blood samples were collected. Weights of liver (LIV), kidney (KID), brain (BRN), epididymal fat (EPI), and perirenal fat (PERI) were also measured. Statistical analysis to compare differences between groups was performed by standard analysis of variance procedures (ANOVA) with a significance level of pLO.05. Results indicated P-AAH housed rats had significantly lower body weights (BW), LIV weights, and LIV/BW than VIV housed rats. FB fed rats had significantly lower blood urea nitrogen (BUN) levels and LIV/BW than CH fed rats. In addition, FB fed rats had significantly higher cholesterol (CHOL) levels, EPI/BW, PERI/BW, and total fat (EPI+PERI)/BW than CH fed rats. The P-AAH+FB group had significantly lower EPI, BRN, and total fat than VIV+FB rats. VIV+FB rats had significantly higher BRN, EPI, PERI, and total fat than VIV+CH rats. Triglycerides (TG), KID, KID/BW, and BRN/BW were not significantly different among treatment groups. These findings provide valuable information regarding cage design and food bar suitability for long-term use on the ISS.

  9. Computational model of gamma irradiation room at ININ

    NASA Astrophysics Data System (ADS)

    Rodríguez-Romo, Suemi; Patlan-Cardoso, Fernando; Ibáñez-Orozco, Oscar; Vergara Martínez, Francisco Javier

    2018-03-01

    In this paper, we present a model of the gamma irradiation room at the National Institute of Nuclear Research (ININ is its acronym in Spanish) in Mexico to improve the use of physics in dosimetry for human protection. We deal with air-filled ionization chambers and scientific computing made in house and framed in both the GEANT4 scheme and our analytical approach to characterize the irradiation room. This room is the only secondary dosimetry facility in Mexico. Our aim is to optimize its experimental designs, facilities, and industrial applications of physical radiation. The computational results provided by our model are supported by all the known experimental data regarding the performance of the ININ gamma irradiation room and allow us to predict the values of the main variables related to this fully enclosed space to within an acceptable margin of error.

  10. FACILITY 363, INTERIOR. LIVING ROOM LOOKING TOWARDS BLACK LANAI. VIEW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FACILITY 363, INTERIOR. LIVING ROOM LOOKING TOWARDS BLACK LANAI. VIEW FACING NORTHWEST. - U.S. Naval Base, Pearl Harbor, Naval Housing Area Hospital Point, Pharmacist's Quarters Type, 13-16 First Street, Pearl City, Honolulu County, HI

  11. 71. FIRST FLOOR, ROOM 101, ENTRANCE HALL (SIDE WITH FIRE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    71. FIRST FLOOR, ROOM 101, ENTRANCE HALL (SIDE WITH FIRE DETECTOR), ARCHWAY TO STAIR HALL 100, LOOKING UP, DETAIL OF ARCHWAY SOFFIT. - Octagon House, 1799 (1741) New York Avenue, Northwest, Washington, District of Columbia, DC

  12. 32. INTERIOR VIEW, MUSIC ROOM LOCATED AT THE NORTHEAST CORNER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. INTERIOR VIEW, MUSIC ROOM LOCATED AT THE NORTHEAST CORNER OF THE HOUSE ON THE FIRST FLOOR, LOOKING TO THE FIREPLACE IN THE EAST WALL - Arlington Place, 331 Cotton Avenue, Southwest, Birmingham, Jefferson County, AL

  13. Geomagnetic field detection in rodents

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Olcese, J.; Reuss, S.; Semm, P.

    1988-01-01

    In addition to behavioral evidence for the detection of earth-strength magnetic fields (MF) by rodents, recent investigations have revealed that electrophysiological and biochemical responses to MF occur in the pineal organ and retina of rodents. In addition, ferrimagnetic deposits have been identified in the ethmoidal regions of the rodent skull. These findings point to a new sensory phenomenon, which interfaces with many fields of biology, including neuroscience, psychophysics, behavioral ecology, chronobiology and sensory physiology.

  14. Controlling allergens in animal rooms by using curtains.

    PubMed

    Krohn, Thomas C; Itter, Gabi; Fosse, Richard; Hansen, Axel K

    2006-05-01

    The reduction and control of allergens in the animal facility is important for staff working with laboratory animals. This study was designed to evaluate the efficiency of perforated Makrolon curtains in front of racks as a method to reduce the amount of allergen in the animal room. The experimental situation we studied provides some information regarding allergen disposition in animal rooms but is clearly artificial and does not reflect a typical, 'real-world' environment in terms of preventing exposure of workers to allergens. Plastic curtains with holes were placed in front of racks, and a corridor between the racks and a curtain was present. The room was ventilated with air, which was blown into the room through the middle of the corridor, flowing downstream and passing through the holes in the curtain. This set-up resulted in air flow from the corridor through the curtain. Air samples were collected from sites in the corridor and behind the curtain. The samples were analyzed for the allergen Mus m1, and the amount of allergen was calculated. The results show air flow from the aisle through the holes in the curtains and through the racks behind the curtains, and this flow keeps allergen behind the curtains and prevents its spread from the cages into the aisle. The present study shows that the use of curtains in front of the cage racks is an efficient way to prevent spread of allergens from rodent cages to the entire animal room.

  15. FACILITY 363, INTERIOR. KITCHEN AS SEEN FROM LIVING ROOM ENTRY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FACILITY 363, INTERIOR. KITCHEN AS SEEN FROM LIVING ROOM ENTRY . VIEW FACING SOUTH. - U.S. Naval Base, Pearl Harbor, Naval Housing Area Hospital Point, Pharmacist's Quarters Type, 13-16 First Street, Pearl City, Honolulu County, HI

  16. 4. FIRSTFLOOR SHOWER/LOCKER ROOM. VIEW TO NORTHEAST. Rocky Mountain ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. FIRST-FLOOR SHOWER/LOCKER ROOM. VIEW TO NORTHEAST. - Rocky Mountain Arsenal, Administration-Laboratory- Change House-Bomb Rail, 420 feet South of December Seventh Avenue; 530 feet West of D Street, Commerce City, Adams County, CO

  17. 12. FRIST FLOOR, SOUTHEAST ROOM, SOUTHWEST WALL, HEARTH WITH KETTLES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. FRIST FLOOR, SOUTHEAST ROOM, SOUTHWEST WALL, HEARTH WITH KETTLES USED FOR RENDERING LARD (LEFT) AND MAKING APPLE BUTTER (RIGHT) - Open Gate Farm, House, Ridge Road, 1 mile East of Elephant Road, Perkasie, Bucks County, PA

  18. 25. MAIN MEETING ROOM STAIRWAY IN SOUTHEAST CORNER. Stairway seen ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    25. MAIN MEETING ROOM STAIRWAY IN SOUTHEAST CORNER. Stairway seen from below showing lath and plaster fireproofing applied to framing before treads and risers. - Twelfth Street Meeting House, 20 South Twelfth Street, Philadelphia, Philadelphia County, PA

  19. Interior view, detail view in first floor drawing room to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior view, detail view in first floor drawing room to show whale oil chandelier and ceiling medallion (duplicate of HABS No. MS-61-A-32) - Melrose, Main House, 1 Melrose-Montebello Parkway, Natchez, Adams County, MS

  20. Virtual reality systems for rodents

    PubMed Central

    Ayaz, Aslı

    2017-01-01

    Abstract Over the last decade virtual reality (VR) setups for rodents have been developed and utilized to investigate the neural foundations of behavior. Such VR systems became very popular since they allow the use of state-of-the-art techniques to measure neural activity in behaving rodents that cannot be easily used with classical behavior setups. Here, we provide an overview of rodent VR technologies and review recent results from related research. We discuss commonalities and differences as well as merits and issues of different approaches. A special focus is given to experimental (behavioral) paradigms in use. Finally we comment on possible use cases that may further exploit the potential of VR in rodent research and hence inspire future studies. PMID:29491968

  1. Room air monitor for radioactive aerosols

    DOEpatents

    Balmer, D.K.; Tyree, W.H.

    1987-03-23

    A housing assembly for use with a room air monitor for simultaneous collection and counting of suspended particles includes a casing containing a combination detector-preamplifier system at one end, a filter system at the other end, and an air flow system consisting of an air inlet formed in the casing between the detector-preamplifier system and the filter system and an air passageway extending from the air inlet through the casing and out the end opposite the detector-preamplifier combination. The filter system collects suspended particles transported directly through the housing by means of the air flow system, and these particles are detected and examined for radioactivity by the detector-preamplifier combination. 2 figs.

  2. TECHNIQUES IN ASEPTIC RODENT SURGERY

    PubMed Central

    Hoogstraten-Miller, Shelley L.; Brown, Patricia A.

    2008-01-01

    Performing aseptic survival surgery in rodents can be challenging. This unit describes some basic principles to assist clinicians, researchers, and technicians in becoming proficient in performing aseptic rodent surgery. PMID:18729061

  3. 75 FR 54020 - Federal Housing Administration Risk Management Initiatives: New Loan-to-Value and Credit Score...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-03

    ... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT 24 CFR Ch. II [Docket No. FR-5404-N-02] Federal... Development, Office of Housing, Department of Housing and Urban Development, 451 7th Street, SW., Room 9278... downpayment. Gifts from family members, charitable organizations, employers, and government entities are also...

  4. Rodent Research-1 Validation of Rodent Hardware

    NASA Technical Reports Server (NTRS)

    Globus, Ruth; Beegle, Janet

    2013-01-01

    To achieve novel science objectives, validation of a rodent habitat on ISS will enable - In-flight analyses during long duration spaceflight- Use of genetically altered animals- Application of modern analytical techniques (e.g. genomics, proteomics, and metabolomics)

  5. 35. SECOND FLOOR, SOUTHEAST ROOM, NORTH WALL: BLACK MARBLE MANTLE. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. SECOND FLOOR, SOUTHEAST ROOM, NORTH WALL: BLACK MARBLE MANTLE. Grape clusters above columns repeat in upper part of cornice and probably in destroyed ceiling centerpiece - Governor Thomas Bennett House, 1 Lucas Street, Charleston, Charleston County, SC

  6. SECOND FLOOR FRONT ROOM, WINDOWS FACING ON WALNUT STREET (SOUTH), ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    SECOND FLOOR FRONT ROOM, WINDOWS FACING ON WALNUT STREET (SOUTH), ORIGINAL PANELED FOLDING SHUTTERS AND HARDWARE. For a view of closed shutters see PA-1436 A-16 - Kid-Chandler House, 323 Walnut Street, Philadelphia, Philadelphia County, PA

  7. 19. ROOM 34 AT WEST END OF LABORATORY, THAT FORMERLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. ROOM 34 AT WEST END OF LABORATORY, THAT FORMERLY HOUSED ROCK CUTTING EQUIPMENT. NOTE BLACKED OUT ORIGINAL WINDOW AT LEFT. - U.S. Geological Survey, Rock Magnetics Laboratory, 345 Middlefield Road, Menlo Park, San Mateo County, CA

  8. Campuses See Rising Demand for Housing

    ERIC Educational Resources Information Center

    Hoover, Eric

    2008-01-01

    The numbers looked strange. In early March, the University of Missouri had received many more campus-housing contracts than it expected. Each year many upperclassmen cancel their agreements after finding an off-campus rental, leaving enough spaces for incoming students. But on March 17, the first day freshmen could select their rooms online, there…

  9. 27. INTERIOR OF UTILITY ROOM SHOWING ELECTRICAL JUNCTION CABINET, HOPPER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. INTERIOR OF UTILITY ROOM SHOWING ELECTRICAL JUNCTION CABINET, HOPPER WINDOW, OPEN DOOR TO KITCHEN NO. 2, AND METAL SINK. VIEW TO SOUTHWEST. - Bishop Creek Hydroelectric System, Plant 6, Cashbaugh-Kilpatrick House, Bishop Creek, Bishop, Inyo County, CA

  10. 16. SECOND FLOOR, EAST ROOM, SHOWING DOORWAYS TO BOXED WINDER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. SECOND FLOOR, EAST ROOM, SHOWING DOORWAYS TO BOXED WINDER STAIRWAYS-- UP AND DOWN-- AND WALL CABINET WITH DOORS OPEN TO SHOW STAIRWAY - High Farm, House, Creek Road, 1 mile West of Easton Road, Pipersville, Bucks County, PA

  11. 11. FIRST FLOOR, NORTHWEST ROOM, GENERAL VIEW OF PARLOR LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. FIRST FLOOR, NORTHWEST ROOM, GENERAL VIEW OF PARLOR LOOKING NORTHWEST TOWARDS CORNER FIREPLACE (THERE WAS ORIGINALLY A WALL BETWEEN THESE FIREPLACES) - Open Gate Farm, House, Ridge Road, 1 mile East of Elephant Road, Perkasie, Bucks County, PA

  12. 13. FRIST FLOOR, SOUTHEAST ROOM, SOUTHWEST WALL, HEARTH WITH KETTLES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. FRIST FLOOR, SOUTHEAST ROOM, SOUTHWEST WALL, HEARTH WITH KETTLES USED FOR RENDERING LARD (LEFT) AND MAKING APPLE BUTTER (RIGHT) WITH SCALE - Open Gate Farm, House, Ridge Road, 1 mile East of Elephant Road, Perkasie, Bucks County, PA

  13. 23. POWER ROOM INTERIOR, DETAIL OF FAIRBANKSMORSE DIESEL ENGINE, DIRECTLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. POWER ROOM INTERIOR, DETAIL OF FAIRBANKS-MORSE DIESEL ENGINE, DIRECTLY CONNECTED TO FAIRBANKS-MORSE 30 KW DC GENERATOR, 125 VOLTS, 240 AMPS, 800 RPM. INSTALLED 1930. - Death Valley Ranch, Power House, Death Valley Junction, Inyo County, CA

  14. The largest fossil rodent

    PubMed Central

    Rinderknecht, Andrés; Blanco, R. Ernesto

    2008-01-01

    The discovery of an exceptionally well-preserved skull permits the description of the new South American fossil species of the rodent, Josephoartigasia monesi sp. nov. (family: Dinomyidae; Rodentia: Hystricognathi: Caviomorpha). This species with estimated body mass of nearly 1000 kg is the largest yet recorded. The skull sheds new light on the anatomy of the extinct giant rodents of the Dinomyidae, which are known mostly from isolated teeth and incomplete mandible remains. The fossil derives from San José Formation, Uruguay, usually assigned to the Pliocene–Pleistocene (4–2 Myr ago), and the proposed palaeoenvironment where this rodent lived was characterized as an estuarine or deltaic system with forest communities. PMID:18198140

  15. DINING ROOM DOOR TO THE CARPORT. VIEW FACING SOUTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DINING ROOM DOOR TO THE CARPORT. VIEW FACING SOUTHEAST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, U-Shaped Two-Bedroom Single-Family Type 6, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  16. Lawsonia intracellularis in the feces of wild rodents and stray cats captured around equine farms.

    PubMed

    Hwang, Jeong-Min; Seo, Myung-Ji; Yeh, Jung-Yong

    2017-08-11

    Proliferative enteropathy is a global enteric disease of particular importance in pigs. The causative bacterium, Lawsonia intracellularis, has a wide range of susceptible host species. Recently, L. intracellularis has been recognized as an etiologic agent of an emerging enteric disease in foals called equine proliferative enteropathy (EPE). The presence of L. intracellularis in nonruminant wildlife has raised questions regarding the role of these species in EPE transmission. This study investigated exposure to L. intracellularis in wild rodents and feral cats from eight farms with confirmed EPE. Serum (42) and fecal (40) samples from resident foals and fecal samples (131), intestinal mucosa tissues (14), and mesenteric lymph nodes (14) from wild and feral animals were collected for the evaluation of the farm status and the molecular detection of L. intracellularis following the diagnosis of EPE in index cases. Fresh feces from wild rodents and feral cats were collected from the ground while walking the premises or after trapping the animals using live traps. A total of 3 brown rats, 7 house mice, 1 striped field mouse, 2 grey red-backed voles, and 3 feral cats showed evidence of prior exposure to L. intracellularis. Our data add to increasing evidence demonstrating the potential for L. intracellularis transmission and infection in wild rodents and feral cats and provide possible evidence of interspecies transmission. The exposure of wild rodents and feral cats provides potential evidence for the spillover of L. intracellularis to wildlife species and raises the question of spillback to horses. Additionally, these animals may represent an indicator of environmental exposure or may be actively involved in the transmission of L. intracellularis to foals by acting as potential reservoir/amplifier hosts. This study is the first to demonstrate the magnitude of L. intracellularis shedding in the feces of wild rodents and feral cats and to indicate the significant

  17. [Studies on the health standard for room temperature in cold regions].

    PubMed

    Meng, Z L

    1990-03-01

    The microclimate of 205 rooms of single storey houses in four new rural residential districts in coastal and inland Shandong was monitored and studied the blood circulation of the finger, skin temperature, sweating function and other physiological indexes among 2,401 peasants. We interrogated their personal sensation to cold and warmth. The count was done by the application of thermal equilibrium index (TEI), predicted 4-hour Sweat Rate (P4SR) and the uncomfortable index. The standard room temperature is recommended as follows. In rural area in winter the appropriate room temperature is 14-16 degrees C, the comfortable room temperature is 16-20 degrees C, the lowest room temperature must not be below 14 degrees C. In summer the appropriate room temperature is 25-28 degrees C, the comfortable room temperature is 26-27 degrees C, the highest temperature must not be above 28 degrees C.

  18. 35. SECOND FLOOR WEST ROOM LOOKING NORTH. The two trusses ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. SECOND FLOOR WEST ROOM LOOKING NORTH. The two trusses above this room date from 1812. They differ from the 1755 salvaged trusses in that they are made of pine rather than poplar, their numbering system differs, and they do not have pockets for joists. These two trusses were added to extend the plan of the building when it was re-erected in 1812. - Twelfth Street Meeting House, 20 South Twelfth Street, Philadelphia, Philadelphia County, PA

  19. TEST METHODS TO CHARACTERIZE PARTICULATE MATTER EMISSIONS AND DEPOSITION RATES IN A RESEARCH HOUSE

    EPA Science Inventory

    The paper discusses test methods to characterize particulate matter (PM) emissions and deposition rates in a research house. In a room in the research house, specially configured for PM source testing, a high-efficiency particulate air (HEPA)-filtered air supply system, used for...

  20. Microclimate monitoring of Ariadne's house (Pompeii, Italy) for preventive conservation of fresco paintings.

    PubMed

    Merello, Paloma; García-Diego, Fernando-Juan; Zarzo, Manuel

    2012-11-28

    Ariadne's house, located at the city center of ancient Pompeii, is of great archaeological value due to the fresco paintings decorating several rooms. In order to assess the risks for long-term conservation affecting the valuable mural paintings, 26 temperature data-loggers and 26 relative humidity data-loggers were located in four rooms of the house for the monitoring of ambient conditions. Data recorded during 372 days were analyzed by means of graphical descriptive methods and analysis of variance (ANOVA). Results revealed an effect of the roof type and number of walls of the room. Excessive temperatures were observed during the summer in rooms covered with transparent roofs, and corrective actions were taken. Moreover, higher humidity values were recorded by sensors on the floor level. The present work provides guidelines about the type, number, calibration and position of thermohygrometric sensors recommended for the microclimate monitoring of mural paintings in outdoor or semi-confined environments.

  1. 28. INTERIOR OF UTILITY ROOM SHOWING STORAGE CLOSET AT PHOTO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. INTERIOR OF UTILITY ROOM SHOWING STORAGE CLOSET AT PHOTO CENTER LEFT AND HOT WATER HEATER CLOSET AT PHOTO CENTER RIGHT. VIEW TO EAST. - Bishop Creek Hydroelectric System, Plant 6, Cashbaugh-Kilpatrick House, Bishop Creek, Bishop, Inyo County, CA

  2. 21. POWER ROOM INTERIOR, DETAIL OF CATERPILLAR DIESEL ENGINE DIRECTLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. POWER ROOM INTERIOR, DETAIL OF CATERPILLAR DIESEL ENGINE DIRECTLY CONNECTED TO GENERAL ELECTRIC 15 KW DC GENERATOR (ON LEFT), 110 VOLTS, 136 AMPS, 1200 RPM. INSTALLED 1942. - Death Valley Ranch, Power House, Death Valley Junction, Inyo County, CA

  3. UTILITY ROOM. VIEW FACING WEST Camp H.M. Smith and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    UTILITY ROOM. VIEW FACING WEST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Three-Bedroom Single-Family Type 7, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  4. FACILITY 89. INTERIOR OF LIVING ROOM, TAKEN THROUGH BEVELED OPENING. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FACILITY 89. INTERIOR OF LIVING ROOM, TAKEN THROUGH BEVELED OPENING. VIEW FACING NORTH. - U.S. Naval Base, Pearl Harbor, Naval Housing Area Makalapa, Junior Officers' Quarters Type K, Makin Place, & Halawa, Makalapa, & Midway Drives, Pearl City, Honolulu County, HI

  5. FIRST FLOOR FRONT ROOM. SECOND FLOOR HAS BEEN REMOVED NOTE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FIRST FLOOR FRONT ROOM. SECOND FLOOR HAS BEEN REMOVED-- NOTE PRESENCE OF SECOND FLOOR WINDOWS (THE LATTER FLOOR WAS REMOVED MANY YEARS AGO), See also PA-1436 B-12 - Kid-Physick House, 325 Walnut Street, Philadelphia, Philadelphia County, PA

  6. WINDOW WITH ORIGINAL PANELED FOLDING SHUTTERS, SECOND FLOOR FRONT ROOM, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    WINDOW WITH ORIGINAL PANELED FOLDING SHUTTERS, SECOND FLOOR FRONT ROOM, LOOKING OUT WALNUT STREET (SOUTH). NOTE ALTERED LOWER SECTION MADE CA. 1840. Compare window in PA-1436 A-37 - Kid-Chandler House, 323 Walnut Street, Philadelphia, Philadelphia County, PA

  7. 8. FIRST FLOOR, EAST ROOM, NORTHEAST WALL SHOWING DOORWAYS TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. FIRST FLOOR, EAST ROOM, NORTHEAST WALL SHOWING DOORWAYS TO BOXED WINDER STAIRWAYS, UP ON FAR RIGHT AND DOWN TO RIGHT OF FIREPLACE, WITH SHUTTERS OPEN - High Farm, House, Creek Road, 1 mile West of Easton Road, Pipersville, Bucks County, PA

  8. INTERIOR VIEW OF DEBITEUSE ROOM. MONORAIL USED TO MOVE DEBIS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR VIEW OF DEBITEUSE ROOM. MONORAIL USED TO MOVE DEBIS IS FROM ORIGINAL CLAY HOUSE. VIEW SHOWS WORKER USING AIR HAMMER TO BEGIN FINISH ON DEBI. - Chambers-McKee Window Glass Company, Debiteuse, Clay Avenue Extension, Jeannette, Westmoreland County, PA

  9. DINING ROOM. VIEW FACING NORTHWEST Camp H.M. Smith and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DINING ROOM. VIEW FACING NORTHWEST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Three-Bedroom Single-Family Types 8 and 11, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  10. Rodent growth, behavior, and physiology resulting from flight on the Space Life Sciences-1 mission

    NASA Technical Reports Server (NTRS)

    Jahns, G.; Meylor, J.; Fast, T.; Hawes, N.; Zarow, G.

    1992-01-01

    A rodent-based spaceflight study is conducted to investigate physiological changes in rats vs humans and the effects of changes in the design of the Research Animal Holding Facility (RAHF) and the Animal Enclosure Module (AEM). Rats were housed in the AEM and the RAHF, and controls were kept in identical flight hardware on earth subjected to the same flight-environmental profile. Biosamples and organ weights are taken to compare the rats before and after flight, and food/water intake are also compared. Weight gain, body weight, and food consumptions in the flight rats are significantly lower than corresponding values for the control subjects. Flight rats tend to have smaller postexperiment spleens and hearts, and flight rats consumed more water in the AEM than in the RAHF. The rodents' behavior is analogous to humans with respect to physiological and reconditioning effects, showing that the rat is a good model for basic research into the effects of spaceflight on humans.

  11. 133. 24 EAST 51ST STREET, FRONT DRAWING ROOM, NORTH WALL, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    133. 24 EAST 51ST STREET, FRONT DRAWING ROOM, NORTH WALL, LEADED GLASS WINDOW WITH CARVED WOOD REVEAL AND SURROUND - Villard Houses, 451-457 Madison Avenue & 24 East Fifty-first Street, New York County, NY

  12. Ectoparasites of livestock, dogs, and wild rodents in the Chittagong Hill Tracts in southeastern Bangladesh.

    PubMed

    Fuehrer, Hans-Peter; Igel, Petra; Treiber, Moritz; Baumann, Timo A; Riedl, Julia; Swoboda, Paul; Joachim, Anja; Noedl, Harald

    2012-10-01

    A large variety of ectoparasites parasitizing on livestock, dogs, and rodents are documented throughout the world, of which several are proven vectors for major (including zoonotic) diseases affecting humans and/or livestock. However, there remains a significant lack of knowledge in regard to the ectoparasite fauna in remote regions of the developing world, such as southeastern Bangladesh, and an urgent need to investigate this fauna to improve diagnostic options. In the course of the present study, more than 5,300 ectoparasites were collected by flag dragging and handpicking of livestock, dogs, and rodents in the District of Bandarban (Chittagong Hill Tracts) in southeastern Bangladesh. Three tick species were identified: Haemaphysalis bispinosa (flagging, cattle, goats, and dogs), Rhipicephalus microplus (cattle, goats), and Rhipicephalus sanguineus (dogs, goats, and flagging). H. bispinosa was the dominant tick species on mammalian hosts as well as on vegetation. Furthermore, Ctenocephalides canis (dogs, goats) and Linognatus sp. (goat) were found. Overall, 73 rodents of eight different species (e.g., Mus musculus, Rattus sikkimensis, Bandicota bengalensis, and Niviventer sp.) hosted a variety of ectoparasites such as mites (Laelaps nuttali, Laelaps echidninus, Lyponissoides sp. and Ornithonyssus bacoti), fleas (Xenopsylla cheopis), and one myiasis-causing dipteran species. Monitoring the ectoparasite burden of livestock and other mammals is urgently needed in order to control ectoparasites associated with social and economic burden (e.g., reduced milk production, weight loss). Several zoonotic diseases can be transmitted by ectoparasites in this area, where the majority of the population live in basic housing conditions and in direct contact with livestock, dogs, and rodents.

  13. 60. INTERIOR VIEW OF LOCKKEEPER'S HOUSE I (REMOVED FROM ESPLANADE), ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    60. INTERIOR VIEW OF LOCKKEEPER'S HOUSE I (REMOVED FROM ESPLANADE), SHOWING FIRST FLOOR LIVING ROOM, LOOKING NORTHWEST - Upper Mississippi River 9-Foot Channel Project, Lock & Dam No. 3, Red Wing, Goodhue County, MN

  14. 61. INTERIOR VIEW OF LOCKKEEPER'S HOUSE I (REMOVED FROM ESPLANADE), ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    61. INTERIOR VIEW OF LOCKKEEPER'S HOUSE I (REMOVED FROM ESPLANADE), SHOWING FIRST FLOOR DINING ROOM, LOOKING NORTHWEST - Upper Mississippi River 9-Foot Channel Project, Lock & Dam No. 3, Red Wing, Goodhue County, MN

  15. A Geographic Information Systems (GIS)-based analysis of modern South African rodent distributions, habitat use, and environmental tolerances.

    PubMed

    Campbell, Timothy L; Lewis, Patrick J; Thies, Monte L; Williams, Justin K

    2012-11-01

    GOALS OF THIS STUDY WERE TO: (1) develop distributional maps of modern rodent genera throughout the countries of South Africa, Lesotho, and Swaziland by georeferencing museum specimens; (2) assess habitat preferences for genera by cross-referencing locality position with South African vegetation; and (3) identify mean annual precipitation and temperature range where the genera are located. Conterminous South Africa including the countries of Lesotho and Swaziland Digital databases of rodent museum specimens housed in the Ditsong National Museum of Natural History, South Africa (DM), and the Division of Mammals, National Museum of Natural History, Smithsonian Institution, United States (NMNH), were acquired and then sorted into a subset of specimens with associated coordinate data. The coordinate data were then used to develop distributional maps for the rodent genera present within the study area. Percent habitat occupation and descriptive statistics for six climatic variables were then determined for each genus by cross-referencing locality positions with vegetation and climatic maps. This report presents a series of maps illustrating the distribution of 35 rodent genera based on 19,471 geo-referenced specimens obtained from two major collections. Inferred habitat use by taxon is provided for both locality and specimen percent occurrence at three hierarchical habitat levels: biome, bioregion, and vegetation unit. Descriptive statistics for six climatic variables are also provided for each genus based on locality and specimen percent incidence. As rodent faunas are commonly used in paleoenvironmental reconstructions, an accurate assessment of rodent environmental tolerance ranges is necessary before confidence can be placed in an actualistic model. While the data presented here represent only a subset of the modern geographic distributions for many of the taxa examined, a wide range of environmental regimes are observed, suggesting that more research is necessary

  16. Heat Index in Migrant Farmworker Housing: Implications for Rest and Recovery From Work-Related Heat Stress

    PubMed Central

    Wiggins, Melinda F.; Chen, Haiying; Bischoff, Werner E.; Arcury, Thomas A.

    2013-01-01

    Although the health risk to farmworkers of working in hot conditions is recognized, potential for excessive heat exposure in housing affecting rest and recovery has been ignored. We assessed heat index in common and sleeping rooms in 170 North Carolina farmworker camps across a summer and examined associations with time of summer and air conditioning use. We recorded dangerous heat indexes in most rooms, regardless of time or air conditioning. Policies to reduce heat indexes in farmworker housing should be developed. PMID:23763392

  17. Heat index in migrant farmworker housing: implications for rest and recovery from work-related heat stress.

    PubMed

    Quandt, Sara A; Wiggins, Melinda F; Chen, Haiying; Bischoff, Werner E; Arcury, Thomas A

    2013-08-01

    Although the health risk to farmworkers of working in hot conditions is recognized, potential for excessive heat exposure in housing affecting rest and recovery has been ignored. We assessed heat index in common and sleeping rooms in 170 North Carolina farmworker camps across a summer and examined associations with time of summer and air conditioning use. We recorded dangerous heat indexes in most rooms, regardless of time or air conditioning. Policies to reduce heat indexes in farmworker housing should be developed.

  18. 9. FIRST FLOOR, EAST ROOM, NORTHEAST WALL, SHOWING DOORWAYS TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. FIRST FLOOR, EAST ROOM, NORTHEAST WALL, SHOWING DOORWAYS TO BOXED WINDER STAIRWAYS, UP ON FAR RIGHT AND DOWN TO RIGHT OF FIREPLACE, WITH SHUTTERS OVER FIREPLACE CLOSED - High Farm, House, Creek Road, 1 mile West of Easton Road, Pipersville, Bucks County, PA

  19. 19. POWER ROOM INTERIOR, PELTON WATER TURBINE AND FLYBALL GOVERNOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. POWER ROOM INTERIOR, PELTON WATER TURBINE AND FLYBALL GOVERNOR DIRECTLY CONNECTED TO 7 KW AC GENERATOR (ON RIGHT), 125 VOLTS, 56 AMPS. INSTALLED IN 1926, STILL IN USE FOR OUTSIDE LIGHTING. - Death Valley Ranch, Power House, Death Valley Junction, Inyo County, CA

  20. 46. INTERIOR VIEW, MUSIC ROOM LOCATED AT THE NORTHEAST CORNER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    46. INTERIOR VIEW, MUSIC ROOM LOCATED AT THE NORTHEAST CORNER OF THE HOUSE ON THE FIRST FLOOR, LOOKING TO THE FIREPLACE IN THE EAST WALL (DUPLICATE OF HABS No. AL-424-32) - Arlington Place, 331 Cotton Avenue, Southwest, Birmingham, Jefferson County, AL

  1. 47. INTERIOR VIEW, DINING ROOM LOCATED AT THE SOUTHEAST CORNER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    47. INTERIOR VIEW, DINING ROOM LOCATED AT THE SOUTHEAST CORNER OF THE HOUSE ON THE FIRST FLOOR, LOOKING TO THE FIREPLACE IN THE EAST WALL (DUPLICATE OF HABS No. AL-424-33) - Arlington Place, 331 Cotton Avenue, Southwest, Birmingham, Jefferson County, AL

  2. Life after hospital: trials of a boarding house 'mother'.

    PubMed

    Bailey, M; Brodaty, H

    1982-12-01

    What is life like for the many psychiatric patients discharged from hospital to boarding houses? The 'mother' of a Sydney boarding house describes how her 'family' has taken root, grown, developed and made a stable home. Many behaviours not tolerated in the community (e.g. public masturbation) are acceptable in the home but there are limits and rules (e.g. not in the dining room). A good home needs the responsible person to be open, honest, understanding and sensitive to changes in guests. Psychiatric services and welfare agencies need to recognise the major contributions of well-run boarding houses and need to liaise more with the proprietors.

  3. The House of Children. Lecture, Kodaikanal, 1944

    ERIC Educational Resources Information Center

    Montessori, Maria

    2013-01-01

    This article vividly describes the indoor and outdoor components of what Montessori calls Home Sweet Home. Her vision of a domestic Children's House contains many facets: rooms of varied space, beautiful flooring, gardens that educate and evoke collaboration, and places for year-round exercise. This is a definitive yet rare Montessori article that…

  4. The rodent ultrasound production mechanism.

    PubMed

    Roberts, L H

    1975-03-01

    Rodents produce two types of sounds, audible and ultrasonic, that differ markedly in physical structure. Studies of sound production in light gases show that whereas the audible cries appear to be produced, as in the case of most other mammals, by vibrating structures in the larynx, the ultrasonic cries are produced by a different mechanism, probably a whistle. 'Bird-call' whistles are shown to have all the properties of rodent ultrasonic cries and to mimic them in almost every detail. Thus it is concluded that rodents have two distinct sound production mechanisms, one for audible cries and one for ultrasonic cries.

  5. Housing improvement projects in Indonesia: responding to local demand.

    PubMed

    Josodipoero, R I

    2003-06-01

    For more than three decades, environmental health programmes in Indonesia have emphasized prevention and treatment of the high incidence of disease among villagers. One of the main causes of disease is the unhygienic conditions of typical rural houses - two-room constructions with dirt floors and walls of lightly fired bricks or woven bamboo skins. While most houses have few or no windows, the occupants frequently cook, eat, sleep and even keep animals in a single room. The main objective of the housing improvement programme was to improve air circulation and introduce more sunlight to kill bacteria, avoid dampness and eliminate smoke from cooking. The programme encourages villagers to construct a permanent floor, enlarge existing windows or insert new windows for good ventilation. This presentation will share the 'success stories' of housing improvement projects in Indonesia that adopted demand-responsive approaches instead of the conventional 'supply approach'. Through exercises like Wealth Classification and Social Mapping, a demand-responsive approach lets the community decide who is eligible for assistance, resulting in higher participation and accurate information on community demand and on materials needed. In addition to the successes, the failures will be discussed at field level. This presentation will discuss the lessons learned from: the World Bank-funded Kalisemut Case Study; government's Family Welfare Movement; Plan International's project in Yogyakarta, and AusAID-funded Sustainable Development through Community Participation Project in Lombok.

  6. Microclimate monitoring of Ariadne’s house (Pompeii, Italy) for preventive conservation of fresco paintings

    PubMed Central

    2012-01-01

    Background Ariadne’s house, located at the city center of ancient Pompeii, is of great archaeological value due to the fresco paintings decorating several rooms. In order to assess the risks for long-term conservation affecting the valuable mural paintings, 26 temperature data-loggers and 26 relative humidity data-loggers were located in four rooms of the house for the monitoring of ambient conditions. Results Data recorded during 372 days were analyzed by means of graphical descriptive methods and analysis of variance (ANOVA). Results revealed an effect of the roof type and number of walls of the room. Excessive temperatures were observed during the summer in rooms covered with transparent roofs, and corrective actions were taken. Moreover, higher humidity values were recorded by sensors on the floor level. Conclusions The present work provides guidelines about the type, number, calibration and position of thermohygrometric sensors recommended for the microclimate monitoring of mural paintings in outdoor or semi-confined environments. PMID:23190798

  7. Particulate pollution in different housing types in a UK suburban location.

    PubMed

    Nasir, Zaheer Ahmad; Colbeck, Ian

    2013-02-15

    To investigate the levels of particulate pollution in residential built environments measurements of PM(10), PM(2.5), and PM(1) and concentrations were made between 2004 and 2008 in various residencies in a UK suburban location. Measurements were carried out in three different residential settings (Types I, II and III). In type I non-smoking living rooms, the highest 24-hour mean concentrations were found in summer. When smoking took place in type I residences, the concentrations of PM(10), PM(2.5) and PM(1), during the winter were almost double those in summer. In type II houses the concentrations were higher in the houses with open plan kitchens than in those with separate kitchens. In type III houses, mean concentrations were significantly higher in wood heated living rooms than those using central heating. In kitchens, cooking resulted in substantially higher concentrations of particulate matter with levels above those in smoking living rooms in winter. The hourly maximum values of number concentration were considerably higher in smoking rooms than non-smoking ones. Cooking resulted in increased number concentrations, with the average hourly maximum concentration of 179,110 #/cm(3). Particle mass and number emission rates were determined for a number of activities. In kitchens grilling had the highest average number emission rate, followed by boiling and frying. The results clearly highlight the impact of different forms of dwelling and their use and management by occupants on the levels of particulate matter in naturally ventilated residential built environments. Copyright © 2012 Elsevier B.V. All rights reserved.

  8. Population dynamics of introduced rodents in Hawaii Volcanoes National Park 1986-1990

    USGS Publications Warehouse

    Scheffler, Pamela Y.; Foote, D.; Forbes-Perry, Charlotte; Schlappa, K.; Stone, Charles P.

    2012-01-01

    We determined seasonal and geographical distribution patterns for four species of introduced rodents in Hawai‘i Volcanoes National Park from 1986-1990. We surveyed black rats (Rattus rattus), Polynesian rats (R. exulans), Norway rats (R. norvegicus) and house mice (Mus musculus) along an elevation gradient ranging from 90–1,820 m above sea level in five different sites using baited snap traps. Rodent community structure differed by elevation: there were more mice at montane sites and more Polynesian rats in the lowlands. We found that breeding occurred throughout the year for all species at all sites but that seasonal peaks in reproductive activity were common. Reproduction tended to be more common in the summer months at higher elevation sites and in the winter months at lower elevations. Rodents of all species were more abundant in our study in the winter than in the summer, but the differences were not significant. The overall sex ratio did not vary from a 1:1 ratio, but seasonally there were differences in sex ratio which varied with species and site. We calculated the minimum distance traveled from an assessment line and found that larger-bodied species traveled longer average distances. Pelage color in black rats was darkest in wet forest which may have adaptive value. Black and Polynesian rats were widespread in almost all habitat types, whereas mice were limited to dry and mesic sites; Norway rats were the rarest component of our sampling and found only in wet montane forest (‘Ōla‘a Forest).

  9. DETAIL OF TYPICAL BASEBOARD IN LIVING ROOM. VIEW FACING SOUTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL OF TYPICAL BASEBOARD IN LIVING ROOM. VIEW FACING SOUTH - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Four-Bedroom, Single-Family Type 10, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  10. 14. INTERIOR OF LIVING ROOM NO. 1 SHOWING DOORWAY TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. INTERIOR OF LIVING ROOM NO. 1 SHOWING DOORWAY TO KITCHEN NO. 2 AND 6-LIGHT OVER 6-LIGHT, DOUBLE-HUNG WINDOWS ALONG BACK (NORTH) WALL. VIEW TO NORTHEAST. - Bishop Creek Hydroelectric System, Plant 6, Cashbaugh-Kilpatrick House, Bishop Creek, Bishop, Inyo County, CA

  11. Clean Room in the Zero Gravity Research Facility

    NASA Image and Video Library

    1968-07-21

    A technician prepares a test sample in the Zero Gravity Research Facility clean room at the National Aeronautics and Space Administration (NASA) Lewis Research Center. The Zero Gravity Research Facility contained a drop tower which provided five seconds of microgravity during freefall in its 450-foot deep vacuum chamber. The facility has been used for a variety of studies relating to the behavior of fluids and flames in microgravity. During normal operations, a cylindrical 3-foot diameter and 11-foot long vehicle was used to house the experiments, instrumentation, and high speed cameras. The 4.5-foot long and 1.5-foot wide rectangular vehicle, seen in this photograph, was used less frequently. A 3-foot diameter orb was used for the special ten-second drops in which the package was pneumatically shot to the top of the tower then dropped. The facility also contained a control room, shop offices, tool and equipment rooms, and this clean room. The 242.5-foot long and 19.5-foot wide clean room was equipped with specialized cleaning equipment. In the 1960s the room was rated as a class 10,000 clean room, but I was capable of meeting the class 100 requirements. The room included a fume hood, ultrasonic cleaner, and a laminar flow station which operated as a class 100 environment. The environment in the clean room was maintained at 71° F and a relative humidity of 45- percent.

  12. Gait Analysis Methods for Rodent Models of Osteoarthritis

    PubMed Central

    Jacobs, Brittany Y.; Kloefkorn, Heidi E.; Allen, Kyle D.

    2014-01-01

    Patients with osteoarthritis (OA) primarily seek treatment due to pain and disability, yet the primary endpoints for rodent OA models tend to be histological measures of joint destruction. The discrepancy between clinical and preclinical evaluations is problematic, given that radiographic evidence of OA in humans does not always correlate to the severity of patient-reported symptoms. Recent advances in behavioral analyses have provided new methods to evaluate disease sequelae in rodents. Of particular relevance to rodent OA models are methods to assess rodent gait. While obvious differences exist between quadrupedal and bipedal gait sequences, the gait abnormalities seen in humans and in rodent OA models reflect similar compensatory behaviors that protect an injured limb from loading. The purpose of this review is to describe these compensations and current methods used to assess rodent gait characteristics, while detailing important considerations for the selection of gait analysis methods in rodent OA models. PMID:25160712

  13. UTILITY ROOM SHOWING THE JALOUSIE PANEL REAR DOOR. VIEW FACING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    UTILITY ROOM SHOWING THE JALOUSIE PANEL REAR DOOR. VIEW FACING NORTHEAST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, U-Shaped Two-Bedroom Single-Family Type 6, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  14. VIEW OF LIVING ROOM DOORS SHOWN IN CLOSED POSITION. VIEW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF LIVING ROOM DOORS SHOWN IN CLOSED POSITION. VIEW FACING WEST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Three-Bedroom Single-Family Type 9, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  15. 24 CFR Appendix A to Part 15 - Location Information for HUD FOIA Reading Rooms and Contact Information for Regional Counsel

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Location Information for HUD FOIA Reading Rooms and Contact Information for Regional Counsel A Appendix A to Part 15 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development PUBLIC ACCESS TO HUD RECORDS...

  16. 4. INTERIOR VIEW OF CLUB HOUSE REFRIGERATION UNIT, SHOWING COOLING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. INTERIOR VIEW OF CLUB HOUSE REFRIGERATION UNIT, SHOWING COOLING COILS AND CORK-LINED ROOM. CAMERA IS BETWEEN SEVEN AND EIGHT FEET ABOVE FLOOR LEVEL, FACING SOUTHEAST. - Swan Falls Village, Clubhouse 011, Snake River, Kuna, Ada County, ID

  17. Cooking and Eating Facilities in Migrant Farmworker Housing in North Carolina

    PubMed Central

    Summers, Phillip; Bischoff, Werner E.; Chen, Haiying; Wiggins, Melinda F.; Spears, Chaya R.; Arcury, Thomas A.

    2013-01-01

    Objectives. We sought to (1) describe observed cooking and eating facilities in migrant farmworker camps, (2) compare observed conditions with existing farmworker housing regulations, and (3) examine associations of violations with camp characteristics. Methods. We collected data in 182 farmworker camps in eastern North Carolina during the 2010 agricultural season. We compared our observations with 15 kitchen-related housing regulations specified by federal and state housing standards. Results. We observed violations of 8 regulations in at least 10% of camps: improper refrigerator temperature (65.5%), cockroach infestation (45.9%), contaminated water (34.4%), rodent infestation (28.9%), improper flooring (25.8%), unsanitary conditions (21.2%), improper fire extinguisher (19.9%), and holes or leaks in walls (12.1%). Logistic regression showed that violations were related to the time of the agricultural season, housing type, number of dwellings and residents, and presence of workers with H-2A visas. Conclusions. Cooking and eating facilities for migrant farmworkers fail to comply with regulations in a substantial number of camps. Greater enforcement of regulations, particularly during occupancy during the agricultural season, is needed to protect farmworkers. PMID:23327274

  18. Hellish conditions at single-room occupancy hotels.

    PubMed

    Foley, D

    1998-08-01

    Poor conditions exist in many of the commercial single-room occupancy (SRO) hotels for people who are HIV-positive. Living conditions are unsanitary, brutal, and dangerous, and occupants often experience harassment from the hotel owners and staff. Many of the occupants are drug abusers or are mentally incapacitated, and therefore may not have the ability to secure better housing. The situation in the California Suites, an SRO in Manhattan, is described.

  19. Mice prefer draught-free housing.

    PubMed

    Krohn, T C; Hansen, A K

    2010-10-01

    An increasing number of rodents are housed in individually ventilated cage (IVC) systems, as these seem to be very effective for the protection of animals against infections, as well as protecting the staff against allergens. For the IVC systems to be properly ventilated, a huge amount of air has to be blown into the cage, which may cause a draught at animal level inside the cage. The aim of the present study was to evaluate the preferences of mice for differing levels of air speeds and air changes inside the cage. It has been concluded that mice do react to draughts, whereas they do not seem to be affected by a high number of air changes delivered without draught, which underlines the importance of applying draught-free IVC systems for mice.

  20. INTERIOR VIEW OF TANK CHARGING ROOM ON LEVEL 4; NOTE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR VIEW OF TANK CHARGING ROOM ON LEVEL 4; NOTE HERRINGBONE-PATTERNED BRICK FLOOR; TIMBER SUBSTRUCTURE CARRIED CRANE USED TO REMOVE HEAVY TANK COVERS; WINDOWS IN ROOFTOP MONITOR PROVIDED AMPLE NATURAL LIGHT - Rath Packing Company, Inedible Tank House, Sycamore Street between Elm & Eighteenth Streets, Waterloo, Black Hawk County, IA

  1. 45. MAIN MEETING ROOM COLUMNS. Ends of gallery columns identified ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    45. MAIN MEETING ROOM COLUMNS. Ends of gallery columns identified at the time of removal for transfer to the George School for re-erection. The stamp reads, 'REMOVED FROM 12th ST. MTG HSE PHILA 1972'. - Twelfth Street Meeting House, 20 South Twelfth Street, Philadelphia, Philadelphia County, PA

  2. DINING ROOM SHOWING DOOR TO LANAI AND PASS THRU TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DINING ROOM SHOWING DOOR TO LANAI AND PASS THRU TO KITCHEN (RIGHT). VIEW FACING SOUTHEAST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Three-Bedroom Single-Family Type 7, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  3. UTILITY ROOM WITH CANEC PANEL CEILING AND TONGUE AND GROOVE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    UTILITY ROOM WITH CANEC PANEL CEILING AND TONGUE AND GROOVE WALL BOARDS. VIEW FACING NORTHWEST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Four-Bedroom, Single-Family Type 10, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  4. FOYER SHOWING WOOD GRILLE AT THE LIVING ROOM AND HALL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FOYER SHOWING WOOD GRILLE AT THE LIVING ROOM AND HALL TO BEDROOMS. VIEW FACING SOUTH - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Four-Bedroom, Single-Family Type 10, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  5. DINING ROOM. NOTE THE RECESSED PULLS ON THE SLIDING DOORS. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DINING ROOM. NOTE THE RECESSED PULLS ON THE SLIDING DOORS. VIEW FACING EAST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, U-Shaped Two-Bedroom Single-Family Type 6, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  6. VIEW OF UTILITY ROOM, SHOWING ORIGINAL REAR DOOR WITH GLASS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF UTILITY ROOM, SHOWING ORIGINAL REAR DOOR WITH GLASS JALOUSIES. VIEW FACING SOUTHWEST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Three-Bedroom Single-Family Type 9, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  7. [Zoo-anthroponoses involving rodents: epidemiologic considerations].

    PubMed

    Rodhain, F

    1996-01-01

    A large number of zoo-anthroponoses is known, in the natural cycle of which are involved rodents or lagomorphs. This is mainly related to the numerical importance of rodents, their ecological plasticity, their relationships with man. Thus, it is important, for the epidemiologist, to differentiate synanthropic rodents living in close contact with man and often spread by him, which are at the origine of frequently urban diseases, from wild rodents usually having only few contacts with man in rural areas only. The events allowing the passage of an infectious agent from rodent to man appear varied, as are epidemiological schemes in which these animals can play different roles: they can act, alone or together with other animals, as natural reservoirs, or, on the contrary, they are only occasionally infected, and the transmission can occur by direct contact, by bite, through the environment, or with the help of an arthropod vector. It is particularly interesting to follow the evolution of some of these epidemiological systems, in order to evaluate the impact of human activities, such as deforestations, new technics for agriculture and cattle breeding, urbanization, increasing transportation, development of leisure activities. In order to reduce this infectious risk, we should look for the means of a correct balance between rodent and human populations, by joining the control of epidemiologically dangerous species, modification of some of our behaviours, a relevant health information, together with the care of the protection of natural ecosystems.

  8. Predictors for presence and abundance of small mammals in households of villages endemic for commensal rodent plague in Yunnan Province, China

    PubMed Central

    Yin, Jia-Xiang; Geater, Alan; Chongsuvivatwong, Virasakdi; Dong, Xing-Qi; Du, Chun-Hong; Zhong, You-Hong; McNeil, Edward

    2008-01-01

    Background Ninety-one rodent plague epidemics have occurred in Lianghe county, Yunnan Province, China, between 1990 and 2006. This study aimed to identify predictors for the presence and abundance of small mammals in households of villages endemic for rodent plague in Lianghe county. Results Rattus flavipectus and Suncus murinus were the two species captured in 110 households. Keeping cats decreased the number of captures of R. flavipectus by one to two thirds and the chance of reported small mammal sightings in houses by 60 to 80%. Food availability was associated with fewer captures. Keeping food in sacks decreased the small mammal captures, especially of S. murinus 4- to 8-fold. Vegetables grown around house and maize grown in the village reduced the captures of S. murinus and R. flavipectus by 73 and 45%, respectively. An outside toilet and garbage piles near the house each reduced R. flavipectus captures by 39 and 37%, respectively, while raising dogs and the presence of communal latrines in the village increased R. flavipectus captures by 76 and 110% but were without detectable effect on small mammal sightings. Location adjacent to other houses increased captures 2-fold but reduced the chance of sightings to about half. In addition, raising ducks increased the chance of sighting small mammals 2.7-fold. Even after adjusting for these variables, households of the Dai had higher captures than those of the Han and other ethnic groups. Conclusion Both species captures were reduced by availability of species-specific foods in the environment, whereas other predictors for capture of the two species differed. Other than the beneficial effect of cats, there were also discrepancies between the effects on small mammal captures and those on sightings. These differences should be considered during the implementation and interpretation of small mammal surveys. PMID:19068139

  9. Data mining of space heating system performance in affordable housing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ren, Xiaoxin; Yan, Da; Hong, Tianzhen

    The space heating in residential buildings accounts for a considerable amount of the primary energy use. Therefore, understanding the operation and performance of space heating systems becomes crucial in improving occupant comfort while reducing energy use. This study investigated the behavior of occupants adjusting their thermostat settings and heating system operations in a 62-unit affordable housing complex in Revere, Massachusetts, USA. The data mining methods, including clustering approach and decision trees, were used to ascertain occupant behavior patterns. Data tabulating ON/OFF space heating states was assessed, to provide a better understanding of the intermittent operation of space heating systems inmore » terms of system cycling frequency and the duration of each operation. The decision tree was used to verify the link between room temperature settings, house and heating system characteristics and the heating energy use. The results suggest that the majority of apartments show fairly constant room temperature profiles with limited variations during a day or between weekday and weekend. Data clustering results revealed six typical patterns of room temperature profiles during the heating season. Space heating systems cycled more frequently than anticipated due to a tight range of room thermostat settings and potentially oversized heating capacities. In conclusion, from this study affirm data mining techniques are an effective method to analyze large datasets and extract hidden patterns to inform design and improve operations.« less

  10. Data mining of space heating system performance in affordable housing

    DOE PAGES

    Ren, Xiaoxin; Yan, Da; Hong, Tianzhen

    2015-02-16

    The space heating in residential buildings accounts for a considerable amount of the primary energy use. Therefore, understanding the operation and performance of space heating systems becomes crucial in improving occupant comfort while reducing energy use. This study investigated the behavior of occupants adjusting their thermostat settings and heating system operations in a 62-unit affordable housing complex in Revere, Massachusetts, USA. The data mining methods, including clustering approach and decision trees, were used to ascertain occupant behavior patterns. Data tabulating ON/OFF space heating states was assessed, to provide a better understanding of the intermittent operation of space heating systems inmore » terms of system cycling frequency and the duration of each operation. The decision tree was used to verify the link between room temperature settings, house and heating system characteristics and the heating energy use. The results suggest that the majority of apartments show fairly constant room temperature profiles with limited variations during a day or between weekday and weekend. Data clustering results revealed six typical patterns of room temperature profiles during the heating season. Space heating systems cycled more frequently than anticipated due to a tight range of room thermostat settings and potentially oversized heating capacities. In conclusion, from this study affirm data mining techniques are an effective method to analyze large datasets and extract hidden patterns to inform design and improve operations.« less

  11. Control of Domestic Rats & Mice, Training Guide--Rodent Control Series.

    ERIC Educational Resources Information Center

    Bjornson, Bayard F.; And Others

    As one booklet in a series on rodent control, this training guide has been developed to assist administrators, rodent-control operators, and others responsible for rodent-control operations in the training of employees in this field. Topics covered include rodents and human welfare, description and habits of domestic rats and mice, rodent-borne…

  12. Rodent-vegetation relationships in southeastern Montana

    Treesearch

    James G. MacCracken; Daniel W. Uresk; Hansen; Richard M.

    1985-01-01

    Plant communities of southeastern Montana were surveyed for rodents over a two year period. Deer mice (Peromyscus maniculatus) were the most abundant rodent species found on the study area. Prairie voles (Microtus ochrogaster), meadow voles (M. pennsylvanicus), sagebrush voles (Lagurus curtatus...

  13. Lurking in the Shadows: Emerging Rodent Infectious Diseases

    PubMed Central

    Besselsen, David G.; Franklin, Craig L.; Livingston, Robert S.; Riley, Lela K.

    2013-01-01

    Rodent parvoviruses, Helicobacter spp., murine norovirus, and several other previously unknown infectious agents have “emerged” in laboratory rodents relatively recently. These agents have been discovered serendipitously or through active investigation of atypical serology results, cell culture contamination, unexpected histopathology, or previously unrecognized clinical disease syndromes. The potential research impact of these agents is not fully known. Infected rodents have demonstrated immunomodulation, tumor suppression, clinical disease (particularly in immunodeficient rodents), and histopathology. Perturbations of organismal and cellular physiology also likely occur. These agents posed unique challenges to laboratory animal resource programs once discovered; it was necessary to develop specific diagnostic assays and an understanding of their epidemiology and transmission routes before attempting eradication, and then evaluate eradication methods for efficacy. Even then management approaches varied significantly, from apathy to total exclusion, and such inconsistency has hindered the sharing and transfer of rodents among institutions, particularly for genetically modified rodent models that may not be readily available. As additional infectious agents are discovered in laboratory rodents in coming years, much of what researchers have learned from experiences with the recently identified pathogens will be applicable. This article provides an overview of the discovery, detection, and research impact of infectious agents recently identified in laboratory rodents. We also discuss emerging syndromes for which there is a suspected infectious etiology, and the unique challenges of managing newly emerging infectious agents. PMID:18506061

  14. Room air monitor for radioactive aerosols

    DOEpatents

    Balmer, David K.; Tyree, William H.

    1989-04-11

    A housing assembly for use with a room air monitor for simultaneous collection and counting of suspended particles includes a casing containing a combination detector-preamplifier system at one end, a filter system at the other end, and an air flow system consisting of an air inlet formed in the casing between the detector-preamplifier system and the filter system and an air passageway extending from the air inlet through the casing and out the end opposite the detector-preamplifier combination. The filter system collects suspended particles transported directly through the housing by means of the air flow system, and these particles are detected and examined for radioactivity by the detector-pre The U.S. Government has rights in this invention pursuant to Contract No. DE-AC04-76DP03533 between the Department of Energy and Rockwell International Corporation.

  15. Interior of processing room. Scale is in front of windows ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior of processing room. Scale is in front of windows for weighing shuckers' buckets of oyster meat. Blow tank for thoroughly cleaning the oyster meat and two skimming tables for rinsing and draining can also be seen. - J.C. Lore Oyster House, 14430 Solomons Island Road, Solomons, Calvert County, MD

  16. KITCHEN. NOTE THE DINING ROOM DOOR TO THE CARPORT IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    KITCHEN. NOTE THE DINING ROOM DOOR TO THE CARPORT IN THE BACKGROUND. VIEW FACING EAST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, U-Shaped Two-Bedroom Single-Family Type 6, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  17. KITCHEN SHOWING THE PASS THRU TO DINING ROOM. NOTE THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    KITCHEN SHOWING THE PASS THRU TO DINING ROOM. NOTE THE CANEC PANEL CEILING. VIEW FACING NORTHEAST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Three-Bedroom Single-Family Type 7, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  18. VIEW INTO KITCHEN, SHOWING PASSTHRU TO DINING ROOM ON RIGHT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW INTO KITCHEN, SHOWING PASS-THRU TO DINING ROOM ON RIGHT HAND SIDE. VIEW FACING WEST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Three-Bedroom Single-Family Type 9, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  19. Comparative analysis of the oral mucosae from rodents and non-rodents: Application to the nonclinical evaluation of sublingual immunotherapy products

    PubMed Central

    Thirion-Delalande, Catherine; Gervais, Frédéric; Fisch, Cécile; Cuiné, Jean; Baron-Bodo, Véronique; Moingeon, Philippe

    2017-01-01

    Background A comparative characterization of the oral mucosa in various animals is needed to identify the best animal model(s) for nonclinical evaluation of sublingual immunotherapy products. With this aim, we studied the histological characteristics and immune cell infiltrates of oral mucosae from common animal species. Methods Three oral regions (i.e. ventral surface of the tongue, mouth floor and cheek) obtained from eight animal species, including rodents (i.e. mice, rats, hamsters, guinea pigs) and non-rodents (i.e. rabbits, dogs, minipigs and monkeys) were characterized by histology and immunohistology in comparison with a human tongue. Results Rodents exhibit a thin keratinized epithelium with low epithelial extensions, whereas non-rodents, most particularly minipigs and monkeys, display a non-keratinized epithelium with larger rete ridges, similarly to humans. Glycogen-rich cells in the superficial epithelial layers are observed in samples from both minipigs, monkeys and humans. Comparable immune subpopulations detected in the 3 oral regions from rodent and non-rodent species include MHC-II+ antigen presenting cells, mostly CD163+ macrophages, located in the lamina propria (LP) and muscle tissue in the vicinity of resident CD3+CD4+ T cells. Limited numbers of mast cells are also detected in the LP and muscle tissue from all species. Conclusion The oral mucosae of minipigs and monkeys are closest to that of humans, and the immune networks are quite similar between all rodents and non-rodents. Taking into account the ethical and logistical difficulties of performing research in the latter species, rodents and especially mice, should preferentially be used for pharmacodynamics/efficacy studies. Our data also support the use of minipigs to perform biodistribution and safety studies of sublingual immunotherapy products. PMID:28886055

  20. 11. BUOY DECK, NEAR PILOT HOUSE SUPERSTRUCTURE, LOOKING TOWARDS HATCH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. BUOY DECK, NEAR PILOT HOUSE SUPERSTRUCTURE, LOOKING TOWARDS HATCH DOOR INTO WINCH ROOM IN THE SUPERSTRUCTURE (LABELED AT PASSAGE & HYDRAULIC MACHINERY ON PLAN). - U.S. Coast Guard Cutter WHITE HEATH, USGS Integrated Support Command Boston, 427 Commercial Street, Boston, Suffolk County, MA

  1. 35. INTERIOR VIEW OF EQUIPMENT HOUSE, SUBMARINE ESCAPE TRAINING TANK, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. INTERIOR VIEW OF EQUIPMENT HOUSE, SUBMARINE ESCAPE TRAINING TANK, PRIOR TO ENLARGEMENT OF ROOM AND INSTALLATION OF TRIPLE-LOCK RECOMPRESSION CHAMBER IN 1957 - U.S. Naval Submarine Base, New London Submarine Escape Training Tank, Albacore & Darter Roads, Groton, New London County, CT

  2. Europe's Housing Squeeze Puts Students in Tight Spots

    ERIC Educational Resources Information Center

    Labi, Aisha

    2008-01-01

    Affordable housing is an elusive commodity for students in Paris and much of the rest of Europe. Many European universities are in cities where property values have soared in recent years--along with higher-education enrollment figures and the number of students vying for rooms. Few of the universities have dormitories, and students are left…

  3. 24 CFR Appendix A to Part 15 - Location Information for HUD FOIA Reading Rooms and Contact Information for Regional Counsel

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Location Information for HUD FOIA Reading Rooms and Contact Information for Regional Counsel A Appendix A to Part 15 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development PUBLIC ACCESS TO HUD RECORDS UNDER THE FREEDOM OF INFORMATION ACT AN...

  4. 24 CFR Appendix A to Part 15 - Location Information for HUD FOIA Reading Rooms and Contact Information for Regional Counsel

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Location Information for HUD FOIA Reading Rooms and Contact Information for Regional Counsel A Appendix A to Part 15 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development PUBLIC ACCESS TO HUD RECORDS UNDER THE FREEDOM OF INFORMATION ACT AN...

  5. 24 CFR Appendix A to Part 15 - Location Information for HUD FOIA Reading Rooms and Contact Information for Regional Counsel

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false Location Information for HUD FOIA Reading Rooms and Contact Information for Regional Counsel A Appendix A to Part 15 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development PUBLIC ACCESS TO HUD RECORDS UNDER THE FREEDOM OF INFORMATION ACT AN...

  6. 24 CFR Appendix A to Part 15 - Location Information for HUD FOIA Reading Rooms and Contact Information for Regional Counsel

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false Location Information for HUD FOIA Reading Rooms and Contact Information for Regional Counsel A Appendix A to Part 15 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development PUBLIC ACCESS TO HUD RECORDS UNDER THE FREEDOM OF INFORMATION ACT AN...

  7. Tornado injuries related to housing in the Plainfield tornado.

    PubMed

    Brenner, S A; Noji, E K

    1995-02-01

    On 28 August 1990, a tornado in Will County, Illinois, caused 29 deaths and more than US $200 million in damage. Risk factors for impact-related morbidity and mortality were studied. A case-control study was conducted of 26 people hospitalized or killed, and 116 injured, randomly selected people who were in houses damaged by the tornado. To obtain information on study subjects, telephone interviews were conducted, and hospital records, coroners' reports, and American Red Cross records were abstracted. Structural details on houses were collected from tax assessor records. Cases were more likely than controls to have been in multistorey houses than in single-storey houses (OR = 3.9; 95% CI: 1.2-13.2). The risk associated with houses built after 1972 (OR = 7.9) and those built from 1962 to 1972 (OR = 2.2) was greater than for those built before 1962 (OR = 1.0; chi 2 for trend = 12.1; P < 0.01). Being in the basement when the tornado hit was protective (OR = 0.1; 95% CI: 0.0-0.4). One-storey houses were safer than multistorey houses, and basements were safer than other rooms. The association of risk with the construction date of the house is a new finding and should be examined in further studies.

  8. View forward in starboard engine room, compartment C1. Note starboard ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View forward in starboard engine room, compartment C-1. Note starboard engine thrust bearing in open housing at bottom center of photograph; note main circulation pump, main steam chest at top of photo. (065) - USS Olympia, Penn's Landing, 211 South Columbus Boulevard, Philadelphia, Philadelphia County, PA

  9. Evaluation of rodent spaceflight in the NASA animal enclosure module for an extended operational period (up to 35 days).

    PubMed

    Moyer, Eric L; Dumars, Paula M; Sun, Gwo-Shing; Martin, Kara J; Heathcote, David G; Boyle, Richard D; Skidmore, Mike G

    2016-01-01

    The National Aeronautics and Space Administration Animal Enclosure Module (AEM) was developed as a self-contained rodent habitat for shuttle flight missions that provides inhabitants with living space, food, water, ventilation, and lighting, and this study reports whether, after minimal hardware modification, the AEM could support an extended term up to 35 days for Sprague-Dawley rats and C57BL/6 female mice for use on the International Space Station. Success was evaluated based on comparison of AEM housed animals to that of vivarium housed and to normal biological ranges through various measures of animal health and well-being, including animal health evaluations, animal growth and body masses, organ masses, rodent food bar consumption, water consumption, and analysis of blood contents. The results of this study confirmed that the AEMs could support 12 adult female C57BL/6 mice for up to 35 days with self-contained RFB and water, and the AEMs could also support 5 adult male Sprague-Dawley rats for 35 days with external replenishment of diet and water. This study has demonstrated the capability and flexibility of the AEM to operate for up to 35 days with minor hardware modification. Therefore, with modifications, it is possible to utilize this hardware on the International Space Station or other operational platforms to extend the space life science research use of mice and rats.

  10. Evaluation of rodent spaceflight in the NASA animal enclosure module for an extended operational period (up to 35 days)

    PubMed Central

    Moyer, Eric L; Dumars, Paula M; Sun, Gwo-Shing; Martin, Kara J; Heathcote, David G; Boyle, Richard D; Skidmore, Mike G

    2016-01-01

    The National Aeronautics and Space Administration Animal Enclosure Module (AEM) was developed as a self-contained rodent habitat for shuttle flight missions that provides inhabitants with living space, food, water, ventilation, and lighting, and this study reports whether, after minimal hardware modification, the AEM could support an extended term up to 35 days for Sprague-Dawley rats and C57BL/6 female mice for use on the International Space Station. Success was evaluated based on comparison of AEM housed animals to that of vivarium housed and to normal biological ranges through various measures of animal health and well-being, including animal health evaluations, animal growth and body masses, organ masses, rodent food bar consumption, water consumption, and analysis of blood contents. The results of this study confirmed that the AEMs could support 12 adult female C57BL/6 mice for up to 35 days with self-contained RFB and water, and the AEMs could also support 5 adult male Sprague-Dawley rats for 35 days with external replenishment of diet and water. This study has demonstrated the capability and flexibility of the AEM to operate for up to 35 days with minor hardware modification. Therefore, with modifications, it is possible to utilize this hardware on the International Space Station or other operational platforms to extend the space life science research use of mice and rats. PMID:28725722

  11. Genetic structure and invasion history of the house mouse (Mus musculus domesticus) in Senegal, West Africa: a legacy of colonial and contemporary times.

    PubMed

    Lippens, C; Estoup, A; Hima, M K; Loiseau, A; Tatard, C; Dalecky, A; Bâ, K; Kane, M; Diallo, M; Sow, A; Niang, Y; Piry, S; Berthier, K; Leblois, R; Duplantier, J-M; Brouat, C

    2017-08-01

    Knowledge of the genetic make-up and demographic history of invasive populations is critical to understand invasion mechanisms. Commensal rodents are ideal models to study whether complex invasion histories are typical of introductions involving human activities. The house mouse Mus musculus domesticus is a major invasive synanthropic rodent originating from South-West Asia. It has been largely studied in Europe and on several remote islands, but the genetic structure and invasion history of this taxon have been little investigated in several continental areas, including West Africa. In this study, we focussed on invasive populations of M. m. domesticus in Senegal. In this focal area for European settlers, the distribution area and invasion spread of the house mouse is documented by decades of data on commensal rodent communities. Genetic variation at one mitochondrial locus and 16 nuclear microsatellite markers was analysed from individuals sampled in 36 sites distributed across the country. A combination of phylogeographic and population genetics methods showed that there was a single introduction event on the northern coast of Senegal, from an exogenous (probably West European) source, followed by a secondary introduction from northern Senegal into a coastal site further south. The geographic locations of these introduction sites were consistent with the colonial history of Senegal. Overall, the marked microsatellite genetic structure observed in Senegal, even between sites located close together, revealed a complex interplay of different demographic processes occurring during house mouse spatial expansion, including sequential founder effects and stratified dispersal due to human transport along major roads.

  12. 20. MAIN MEETING ROOM, NORTHEAST CORNER. The stairway against the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. MAIN MEETING ROOM, NORTHEAST CORNER. The stairway against the north wall on the men's side is original to 1812-13. The glass vestibule partition was added in 1885. It is believed the east stair was added at that time. - Twelfth Street Meeting House, 20 South Twelfth Street, Philadelphia, Philadelphia County, PA

  13. VIEW OF DINING ROOM ENTRY (VIA CARPORT), SHOWING VINYL SIDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF DINING ROOM ENTRY (VIA CARPORT), SHOWING VINYL SIDING AND PANELING THAT HAS BEEN APPLIED. VIEW FACING SOUTHEAST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Three-Bedroom Single-Family Type 9, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  14. CLOSEUP OF STORAGE AND LAUNDRY CLOSETS IN CARPORT. DINING ROOM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CLOSEUP OF STORAGE AND LAUNDRY CLOSETS IN CARPORT. DINING ROOM IS ON FAR LEFT. VIEW FACING SOUTHEAST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Three-Bedroom Single-Family Types 8 and 11, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  15. VIEW THROUGH DECORATIVE GRILLE OF LIVING ROOM, WITH SLIDING DOORS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW THROUGH DECORATIVE GRILLE OF LIVING ROOM, WITH SLIDING DOORS ON THE LEFT HAND SIDE. VIEW FACING NORTH - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Three-Bedroom Single-Family Type 9, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  16. Investigation of gaseous ozone for MRSA decontamination of hospital side-rooms.

    PubMed

    Berrington, A W; Pedler, S J

    1998-09-01

    A domestic, gaseous ozone generator was investigated for use in the decontamination of hospital side-rooms that have housed patients colonized with methicillin-resistant Staphylococcus aureus (MRSA). Three models of bacterial contamination were used. These were exposed to ozone generation in a standard hospital side-room for 4 and 7 h. A methicillin-sensitive and a methicillin-resistant strain of S. aureus were compared. Ozone concentrations of 0.14 ppm were reached, levels which are sufficient to cause mild pulmonary toxicity. Bacterial counts were reduced in the vicinity of the gas generator in most instances, but the effect elsewhere in the room was, at best, limited. MRSA appeared more resistant to the effects of ozone than methicillin-sensitive S. aureus. We conclude that the device tested would be inadequate for the decontamination of such hospital side-rooms.

  17. [A space for women in the Etruscan and Roman houses (VI-I cent. B.C.)?].

    PubMed

    Jolivet, Vincent

    2011-01-01

    The article analyzes the scientific discussion about the existence of a domestic space reserved to women in Etruscan and Roman houses. The hypotesis regarding the existence of a 'gynaeceum' has been recently proposed for the Etruscan houses built on Palatino in Rome (VI cent. B.C.) and for the ancient phase of the Centaurus Protodomus in Pompei. Considering the specific role of Roman matronae as laniferae, and also a substantial equality of social role between Etruscan men and women, it is possible to advance the hypotesis of the existence of a room originally reserved to women (oecus) on one side of the tablinum, the symmetrical room being reserved to men (triclinium).

  18. 4. WEST FACADE, DOOR LEADING TO THE ELECTRICAL ROOM ON ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. WEST FACADE, DOOR LEADING TO THE ELECTRICAL ROOM ON RIGHT. THE DOOR TO THE LEFT IS THE WEST ENTRANCE TO THE CATWALK LOCATED OVER THE STORAGE TANKS. - Rocky Mountain Arsenal, Tank House, Quadrant 1, approximately 1000 feet South of December Seventh Avenue; 2200 feet East of D Street, Commerce City, Adams County, CO

  19. DINING ROOM WITH WINDOWS TO THE ENCLOSED CARPORT AT REAR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DINING ROOM WITH WINDOWS TO THE ENCLOSED CARPORT AT REAR WALL. NOTE JALOUSIE PANEL DOOR TO THE LANAI. VIEW FACING NORTHWEST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Four-Bedroom, Single-Family Type 10, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  20. 11. LIVING ROOM INTERIOR SHOWING BUILTIN CUPBOARD AND OPEN DOOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. LIVING ROOM INTERIOR SHOWING BUILT-IN CUPBOARD AND OPEN DOOR TO KITCHEN ON THE NORTH WALL AT PHOTO CENTER. OPEN DOOR ON WEST WALL AT PHOTO LEFT ENTERS NORTH BEDROOM. VIEW TO NORTH. - Big Creek Hydroelectric System, Big Creek Town, Operator House, Orchard Avenue south of Huntington Lake Road, Big Creek, Fresno County, CA

  1. Design of a Tunable, Room Temperature, Continuous-Wave Terahertz Source and Detector using Silicon Waveguides

    DTIC Science & Technology

    2008-01-30

    that will use conventional diode- or hotomultiplier-tube-based optical detectors , which are xtremely sensitive . . HEATING AND FREE-CARRIER IMITATIONS...CONTRACT NUMBER IN-HOUSE Design of a tunable, room temperature, continuous-wave terahertz source and detector using silicon waveguides 5b. GRANT...B 261Design of a tunable, room temperature, continuous-wave terahertz source and detector using silicon waveguides T. Baehr-Jones,1,* M. Hochberg,1,3

  2. Rodent-borne diseases and their public health importance in Iran.

    PubMed

    Rabiee, Mohammad Hasan; Mahmoudi, Ahmad; Siahsarvie, Roohollah; Kryštufek, Boris; Mostafavi, Ehsan

    2018-04-01

    Rodents are reservoirs and hosts for several zoonotic diseases such as plague, leptospirosis, and leishmaniasis. Rapid development of industry and agriculture, as well as climate change throughout the globe, has led to change or increase in occurrence of rodent-borne diseases. Considering the distribution of rodents throughout Iran, the aim of this review is to assess the risk of rodent-borne diseases in Iran. We searched Google Scholar, PubMed, Science Direct, Scientific Information Database (SID), and Magiran databases up to September 2016 to obtain articles reporting occurrence of rodent-borne diseases in Iran and extract information from them. Out of 70 known rodent-borne diseases, 34 were reported in Iran: 17 (50%) parasitic diseases, 13 (38%) bacterial diseases, and 4 (12%) viral diseases. Twenty-one out of 34 diseases were reported from both humans and rodents. Among the diseases reported in the rodents of Iran, plague, leishmaniasis, and hymenolepiasis were the most frequent. The most infected rodents were Rattus norvegicus (16 diseases), Mus musculus (14 diseases), Rattus rattus (13 diseases), Meriones persicus (7 diseases), Apodemus spp. (5 diseases), Tatera indica (4 diseases), Meriones libycus (3 diseases), Rhombomys opimus (3 diseases), Cricetulus migratorius (3 diseases), and Nesokia indica (2 diseases). The results of this review indicate the importance of rodent-borne diseases in Iran. Considering notable diversity of rodents and their extensive distribution throughout the country, it is crucial to pay more attention to their role in spreading infectious diseases for better control of the diseases.

  3. The Fecal Viral Flora of Wild Rodents

    PubMed Central

    Phan, Tung G.; Kapusinszky, Beatrix; Wang, Chunlin; Rose, Robert K.; Lipton, Howard L.; Delwart, Eric L.

    2011-01-01

    The frequent interactions of rodents with humans make them a common source of zoonotic infections. To obtain an initial unbiased measure of the viral diversity in the enteric tract of wild rodents we sequenced partially purified, randomly amplified viral RNA and DNA in the feces of 105 wild rodents (mouse, vole, and rat) collected in California and Virginia. We identified in decreasing frequency sequences related to the mammalian viruses families Circoviridae, Picobirnaviridae, Picornaviridae, Astroviridae, Parvoviridae, Papillomaviridae, Adenoviridae, and Coronaviridae. Seventeen small circular DNA genomes containing one or two replicase genes distantly related to the Circoviridae representing several potentially new viral families were characterized. In the Picornaviridae family two new candidate genera as well as a close genetic relative of the human pathogen Aichi virus were characterized. Fragments of the first mouse sapelovirus and picobirnaviruses were identified and the first murine astrovirus genome was characterized. A mouse papillomavirus genome and fragments of a novel adenovirus and adenovirus-associated virus were also sequenced. The next largest fraction of the rodent fecal virome was related to insect viruses of the Densoviridae, Iridoviridae, Polydnaviridae, Dicistroviriade, Bromoviridae, and Virgaviridae families followed by plant virus-related sequences in the Nanoviridae, Geminiviridae, Phycodnaviridae, Secoviridae, Partitiviridae, Tymoviridae, Alphaflexiviridae, and Tombusviridae families reflecting the largely insect and plant rodent diet. Phylogenetic analyses of full and partial viral genomes therefore revealed many previously unreported viral species, genera, and families. The close genetic similarities noted between some rodent and human viruses might reflect past zoonoses. This study increases our understanding of the viral diversity in wild rodents and highlights the large number of still uncharacterized viruses in mammals. PMID:21909269

  4. How many food additives are rodent carcinogens?

    PubMed

    Johnson, F M

    2002-01-01

    One generally assumes that chemical agents added to foods are reasonably free of risks to human health, and practically everyone consumes some additives in his or her food daily throughout life. In the United States, the 1958 Food Additives Amendment to the Federal Food, Drug and Cosmetic Act of 1938 requires food manufacturers to demonstrate the safety of food additives to the Food and Drug Administration (FDA). The Amendment contains a provision that prohibits approval of an additive if it is found to cause cancer in humans or animals. In the present study, data from the National Toxicology Program rodent bioassay (NTPRB) were used to identify a sample of approximately 50 rodent-tested additives and other chemicals added to food that had been evaluated independently of the FDA/food industry. Surprisingly, the sample shows more than 40% of these food chemicals to be carcinogenic in one or more rodent groups. If this percentage is extrapolated to all substances added to food in the United States, it would imply that more than 1000 of such substances are potential rodent carcinogens. The NTP and FDA test guidelines use similar, though not necessarily identical, rodent test procedures, including near lifetime exposures to the maximum tolerated dose. The FDA specifies that test chemicals should be administered by the oral route. However, the oral route includes three methods of delivering chemicals, that is, mixed in the food or water or delivered by stomach tube (gavage). The NTP data show only 1 of 18 food chemicals mixed in the food are rodent carcinogens, but 16 of 23 gavage-administered food chemicals are carcinogenic to rodents. The distribution suggests that among orally delivered chemicals, those administered in the feed will more likely prove to be noncarcinogens than chemicals given by gavage. The rodent data also reveal that effects may vary according to dose and genotype, as well as by route of administration, to further complicate extrapolation to humans

  5. Housing for persons with serious mental illness: consumer and service provider preferences.

    PubMed

    Piat, Myra; Lesage, Alain; Boyer, Richard; Dorvil, Henri; Couture, Audrey; Grenier, Guy; Bloom, David

    2008-09-01

    This study evaluated the housing preferences of a representative sample of consumers with serious mental illness living in seven types of housing in Montreal, Quebec, and compared these with their case managers' housing preferences for them. An inventory of all housing for this population was developed in consultation with administrators of three psychiatric hospitals and the regional health board. The inventory included seven categories: housing in a hospital setting, hostels, group homes, foster homes, supervised apartments, social housing (low-income housing or cooperative), and private rooming homes. A stratified random sample of 48 consumers was selected in each category. In all, 315 consumers and their case managers completed the Consumer Housing Preference Survey. Most consumers preferred living in housing that offered them more autonomy than the housing in which they were currently living. Case managers preferred housing that offered some structure, such as supervised apartments. Forty-four percent of consumers preferred to live in their own apartment. More than a third of consumers preferred to live in their current housing. When evaluating housing preferences, it is important to elicit the viewpoints of mental health consumers as well as their case managers. Special attention should be given to the type of housing where consumers currently live. A variety of housing, not just autonomous housing, is needed to meet the specific housing preferences of individuals with serious mental illness.

  6. VIEW OF DINING ROOM WITH SLIDING DOORS IN CLOSED POSITION. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF DINING ROOM WITH SLIDING DOORS IN CLOSED POSITION. WINDOWS ON THE LEFT HAND SIDE HAVE VIEWS INTO THE CARPORT. VIEW FACING NORTH - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Three-Bedroom Single-Family Type 9, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  7. CLOSEUP OF REAR TERRACE, WITH LIVING ROOM WINDOWS ON LEFT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CLOSEUP OF REAR TERRACE, WITH LIVING ROOM WINDOWS ON LEFT SIDE, AND ADDED DOOR TO ENCLOSED CARPORT ON RIGHT SIDE. VIEW FACING WEST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Four-Bedroom, Single-Family Type 10, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

  8. Rodent Habitat On ISS: Spaceflight Effects On Mouse Behavior

    NASA Technical Reports Server (NTRS)

    Ronca, A. E.; Moyer, E. L.; Talyansky, Y.; Padmanabhan, S.; Choi, S.; Gong, C.; Globus, R. K.

    2016-01-01

    The NASA Decadal Survey (2011), Recapturing a Future for Space Exploration: Life and Physical Sciences Research for a New Era, emphasized the importance of expanding NASA life sciences research to long duration, rodent experiments on the International Space Station (ISS). To accomplish this objective, flight hardware, operations, and science capabilities supporting mouse studies in space were developed at NASA Ames Research Center. The first flight experiment carrying mice, Rodent Research Hardware and Operations Validation (Rodent Research-1), was launched on Sept 21, 2014 in an unmanned Dragon Capsule, SpaceX4, exposing the mice to a total of 37 days in space. Ground control groups were maintained in environmental chambers at Kennedy Space Center. Mouse health and behavior were monitored for the duration of the experiment via video streaming. Here we present behavioral analysis of two groups of five C57BL/6 female adult mice viewed via fixed camera views compared with identically housed Ground Controls. Flight (Flt) and Ground Control (GC) mice exhibited the same range of behaviors, including eating, drinking, exploratory behavior, self- and allo-grooming, and social interactions at similar or greater levels of occurrence. Mice propelled themselves freely and actively throughout the Habitat using their forelimbs to push off or by floating from one cage area to another, and they quickly learned to anchor themselves using tails and/or paws. Overall activity was greater in Flt as compared to GC mice, with spontaneous ambulatory behavior including the development of organized ‘circling’ or ‘race-tracking’ behavior that emerged within the first few days of flight and encompassed the primary dark cycle activity for the remainder of the experiment. We quantified the bout frequency, duration and rate of circling with respect to characteristic behaviors observed in the varying stages of the progressive development of circling: flipping utilizing two sides of the

  9. Rodent-borne diseases and their public health importance in Iran

    PubMed Central

    Mahmoudi, Ahmad; Siahsarvie, Roohollah; Kryštufek, Boris; Mostafavi, Ehsan

    2018-01-01

    Background Rodents are reservoirs and hosts for several zoonotic diseases such as plague, leptospirosis, and leishmaniasis. Rapid development of industry and agriculture, as well as climate change throughout the globe, has led to change or increase in occurrence of rodent-borne diseases. Considering the distribution of rodents throughout Iran, the aim of this review is to assess the risk of rodent-borne diseases in Iran. Methodology/Principal finding We searched Google Scholar, PubMed, Science Direct, Scientific Information Database (SID), and Magiran databases up to September 2016 to obtain articles reporting occurrence of rodent-borne diseases in Iran and extract information from them. Out of 70 known rodent-borne diseases, 34 were reported in Iran: 17 (50%) parasitic diseases, 13 (38%) bacterial diseases, and 4 (12%) viral diseases. Twenty-one out of 34 diseases were reported from both humans and rodents. Among the diseases reported in the rodents of Iran, plague, leishmaniasis, and hymenolepiasis were the most frequent. The most infected rodents were Rattus norvegicus (16 diseases), Mus musculus (14 diseases), Rattus rattus (13 diseases), Meriones persicus (7 diseases), Apodemus spp. (5 diseases), Tatera indica (4 diseases), Meriones libycus (3 diseases), Rhombomys opimus (3 diseases), Cricetulus migratorius (3 diseases), and Nesokia indica (2 diseases). Conclusions/Significance The results of this review indicate the importance of rodent-borne diseases in Iran. Considering notable diversity of rodents and their extensive distribution throughout the country, it is crucial to pay more attention to their role in spreading infectious diseases for better control of the diseases. PMID:29672510

  10. Rodents as potential couriers for bioterrorism agents.

    PubMed

    Lõhmus, Mare; Janse, Ingmar; van de Goot, Frank; van Rotterdam, Bart J

    2013-09-01

    Many pathogens that can cause major public health, economic, and social damage are relatively easily accessible and could be used as biological weapons. Wildlife is a natural reservoir for many potential bioterrorism agents, and, as history has shown, eliminating a pathogen that has dispersed among wild fauna can be extremely challenging. Since a number of wild rodent species live close to humans, rodents constitute a vector for pathogens to circulate among wildlife, domestic animals, and humans. This article reviews the possible consequences of a deliberate spread of rodentborne pathogens. It is relatively easy to infect wild rodents with certain pathogens or to release infected rodents, and the action would be difficult to trace. Rodents can also function as reservoirs for diseases that have been spread during a bioterrorism attack and cause recurring disease outbreaks. As rats and mice are common in both urban and rural settlements, deliberately released rodentborne infections have the capacity to spread very rapidly. The majority of pathogens that are listed as potential agents of bioterrorism by the Centers for Disease Control and Prevention and the National Institute of Allergy and Infectious Diseases exploit rodents as vectors or reservoirs. In addition to zoonotic diseases, deliberately released rodentborne epizootics can have serious economic consequences for society, for example, in the area of international trade restrictions. The ability to rapidly detect introduced diseases and effectively communicate with the public in crisis situations enables a quick response and is essential for successful and cost-effective disease control.

  11. Computer-Aided Surgical Simulation in Head and Neck Reconstruction: A Cost Comparison among Traditional, In-House, and Commercial Options.

    PubMed

    Li, Sean S; Copeland-Halperin, Libby R; Kaminsky, Alexander J; Li, Jihui; Lodhi, Fahad K; Miraliakbari, Reza

    2018-06-01

     Computer-aided surgical simulation (CASS) has redefined surgery, improved precision and reduced the reliance on intraoperative trial-and-error manipulations. CASS is provided by third-party services; however, it may be cost-effective for some hospitals to develop in-house programs. This study provides the first cost analysis comparison among traditional (no CASS), commercial CASS, and in-house CASS for head and neck reconstruction.  The costs of three-dimensional (3D) pre-operative planning for mandibular and maxillary reconstructions were obtained from an in-house CASS program at our large tertiary care hospital in Northern Virginia, as well as a commercial provider (Synthes, Paoli, PA). A cost comparison was performed among these modalities and extrapolated in-house CASS costs were derived. The calculations were based on estimated CASS use with cost structures similar to our institution and sunk costs were amortized over 10 years.  Average operating room time was estimated at 10 hours, with an average of 2 hours saved with CASS. The hourly cost to the hospital for the operating room (including anesthesia and other ancillary costs) was estimated at $4,614/hour. Per case, traditional cases were $46,140, commercial CASS cases were $40,951, and in-house CASS cases were $38,212. Annual in-house CASS costs were $39,590.  CASS reduced operating room time, likely due to improved efficiency and accuracy. Our data demonstrate that hospitals with similar cost structure as ours, performing greater than 27 cases of 3D head and neck reconstructions per year can see a financial benefit from developing an in-house CASS program. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  12. Demonstration and Validation of Corrosion-Mitigation Technologies for Mechanical Room Utility Piping and Cooling-Tower Pumps

    DTIC Science & Technology

    2015-05-01

    Infrastructure, Task 2.1” ERDC/CERL TR-15-5 ii Abstract Two critical infrastructure corrosion issues at Fort Bragg, NC, are the cor- rosion of steel utility...piping union joints in mechanical rooms and the cor- rosion of steel pump housings in cooling tower systems. Reliable operation of these components...pump 5 incorporating 316 stainless steel housing. .................................... 19 Figure 13. New pump 5 being installed

  13. Domestic Rodent Control Training Manual: A Training Aid for the Rodent Control Category for Certification of Pesticide Applicators.

    ERIC Educational Resources Information Center

    Childress, William R., Jr.; And Others

    This training manual, designed for training applicants who wish to obtain certification in pesticide application relative to rodent control, covers the following topics: economic factors, public health factors, biological characteristics of domestic rodents, rat and mouse signs, trapping, repellents, poisons, baits, poisoned water, dumps, sewers,…

  14. Pesticide loadings of select organophosphate and pyrethroid pesticides in urban public housing.

    EPA Science Inventory

    We investigated the magnitude and distribution of pyrethroid and organophosphate pesticide loadings within public housing dwellings in Boston, Massachusetts and compared the results using various sampling methods. We collected dust matrices from living room and kitchen in 42 apar...

  15. Building for the future: essential infrastructure for rodent ageing studies.

    PubMed

    Wells, Sara E; Bellantuono, Ilaria

    2016-08-01

    When planning ageing research using rodent models, the logistics of supply, long term housing and infrastructure provision are important factors to take into consideration. These issues need to be prioritised to ensure they meet the requirements of experiments which potentially will not be completed for several years. Although these issues are not unique to this discipline, the longevity of experiments and indeed the animals, requires a high level of consistency and sustainability to be maintained throughout lengthy periods of time. Moreover, the need to access aged stock or material for more immediate experiments poses many issues for the completion of pilot studies and/or short term intervention studies on older models. In this article, we highlight the increasing demand for ageing research, the resources and infrastructure involved, and the need for large-scale collaborative programmes to advance studies in both a timely and a cost-effective way.

  16. VIEW OF BUILDING 778 LOOKING WESTSOUTHWEST. BUILDING 778 HOUSED LAUNDRY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF BUILDING 778 LOOKING WEST-SOUTHWEST. BUILDING 778 HOUSED LAUNDRY FACILITIES, SHOWERS, LOCKER ROOMS, SANITARY FACILITIES, AN ELECTRIC SHOP, MACHINE SHOP, SHEET METAL SHOP, AND INERT GAS STORAGE. (12/7/90) - Rocky Flats Plant, Laundry Facility, Northeast quad of Plant between buildings 776/777 & 707, Golden, Jefferson County, CO

  17. Hantavirus Prevention: Cleanup of Rodent Contamination

    DTIC Science & Technology

    2008-09-01

    Hantaviruses in the Americas may cause human disease involving the lungs, hence the name " hantavirus pulmonary syndrome" (HPS). Since May 1993, a...humans are also found in other rodents, but the number of cases stemming from these hantaviruses is small when compared to SNV. Hantavirus is shed in... HANTAVIRUS PREVENTION: CLEANUP OF RODENT CONTAMINATION Technical Information Paper 18-001-0306

  18. 7 CFR 58.147 - Insect and rodent control program.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Insect and rodent control program. 58.147 Section 58... Service 1 Operations and Operating Procedures § 58.147 Insect and rodent control program. In addition to... made responsible for the performance of a regularly scheduled insect and rodent control program...

  19. 7 CFR 58.247 - Insect and rodent control program.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Insect and rodent control program. 58.247 Section 58... Service 1 Operations and Operating Procedures § 58.247 Insect and rodent control program. In addition to... made responsible for the performance of a regularly scheduled insect and rodent control program as...

  20. 7 CFR 58.147 - Insect and rodent control program.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Insect and rodent control program. 58.147 Section 58... Service 1 Operations and Operating Procedures § 58.147 Insect and rodent control program. In addition to... made responsible for the performance of a regularly scheduled insect and rodent control program...

  1. 7 CFR 58.247 - Insect and rodent control program.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Insect and rodent control program. 58.247 Section 58... Service 1 Operations and Operating Procedures § 58.247 Insect and rodent control program. In addition to... made responsible for the performance of a regularly scheduled insect and rodent control program as...

  2. The MAM rodent model of schizophrenia

    PubMed Central

    Lodge, Daniel J.

    2013-01-01

    Rodent models of human disease are essential to obtain a better understanding of disease pathology, the mechanism of action underlying conventional treatments, as well as for the generation of novel therapeutic approaches. There are a number of rodent models of schizophrenia based on either genetic manipulations, acute or sub-chronic drug administration, or developmental disturbances. The prenatal methylazoxymethanol acetate (MAM) rodent model is a developmental disruption model gaining increased attention because it displays a number of histological, neurophysiological and behavioral deficits analogous to those observed in schizophrenia patients. This unit describes the procedures required to safely induce the MAM phenotype in rats. In addition, we describe a simple behavioral procedure, amphetamine-induced hyper-locomotion, which can be utilized to verify the MAM phenotype. PMID:23559309

  3. INTERIOR VIEW OF THE LIVING ROOM SHOWING THE FLOOR TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR VIEW OF THE LIVING ROOM SHOWING THE FLOOR TO CEILING WINDOWS. NOTE THE OPENING IN THE RIGHT SIDE WALL FOR AN AIR CONDITIONER. VIEW FACING SOUTHWEST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, U-Shaped Three-Bedroom Duplex Type 3, Acacia Road, Birch Circle, and Cedar Drive, Pearl City, Honolulu County, HI

  4. 19. MAIN MEETING ROOM LOOKING SOUTH FROM GALLERY. Note coved ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. MAIN MEETING ROOM LOOKING SOUTH FROM GALLERY. Note coved extension of gallery, erected when offices were built on gallery for the use of the Friends Service Committee in 1936. Note also the short stair balusters resulting from the wide modesty stair stringer provided for the women's side. - Twelfth Street Meeting House, 20 South Twelfth Street, Philadelphia, Philadelphia County, PA

  5. 15. INTERIOR OF ENGINE ROOM, CONTAINING MESTACORLISS CROSSCOMPOUND ENGINE, FOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. INTERIOR OF ENGINE ROOM, CONTAINING MESTA-CORLISS CROSS-COMPOUND ENGINE, FOR 40" BLOOMING MILL. THIS VIEW IS TAKEN FROM THE HIGH-PRESSURE SIDE OF THE ENGINE SHOWING THE HOUSING EXTENSION; TO THE RIGHT, IN THE BACKGROUND, IS THE 24' CAST-IRON FLYWHEEL. - Republic Iron & Steel Company, Youngstown Works, Blooming Mill & Blooming Mill Engines, North of Poland Avenue, Youngstown, Mahoning County, OH

  6. Hunting, Food Preparation, and Consumption of Rodents in Lao PDR

    PubMed Central

    Suwannarong, Kanokwan; Chapman, Robert S.; Lantican, Cecile; Michaelides, Tula; Zimicki, Susan

    2015-01-01

    A cross-sectional study was conducted in 29 villages of Khamkeuth District in Bolikhamxay Province in the Lao PDR during March to May 2013. The study aimed to determine the characteristics associated with rodent consumption and related behaviors among different ethnic groups, ages, and genders. Five-hundred-eighty-four (584) males and females from 18-50 years of age participated in this study. Half of them were Hmong (292, 50%) while 152 respondents were Lao-Tai (26%) or other ethnic groups (140, 24%). Most of the respondents (79.5%) had farming as their main occupation. Prevalences of the studied outcomes were high: 39.9 for hunting or capturing rodents in the previous year, 77.7% for preparing rodents as food, and 86.3% for rodent consumption. Multivariable logistic regression analysis showed that likelihood of these types of rodent contact was more consistently associated with behavioral factors (gathering things from the forest and elsewhere, cultivation-related activities, and taking measures to prevent rodent-borne disease) than with socio-demographic, environmental, or cultural factors. The strongest associations were observed for gathering things; these associations were consistently positive and statistically significant. Although this study did not directly assess rodent-borne zoonosis risk, we believe that study findings raise concern that such risk may be substantial in the study area and other similar areas. Further epidemiological studies on the association between rodent-borne disease infection and rodent hunting, preparation for food, and consumption are recommended. Moreover, further studies are needed on the association between these potential exposure factors (i.e., rodent hunting, preparation for food, and consumption) and rodent-borne infections, especially among ethnic groups like the Hmong in Lao PDR and those in neighboring countries with similar socio-demographic, environmental, behavioral and cultural contexts. PMID:26196134

  7. Hunting, Food Preparation, and Consumption of Rodents in Lao PDR.

    PubMed

    Suwannarong, Kanokwan; Chapman, Robert S; Lantican, Cecile; Michaelides, Tula; Zimicki, Susan

    2015-01-01

    A cross-sectional study was conducted in 29 villages of Khamkeuth District in Bolikhamxay Province in the Lao PDR during March to May 2013. The study aimed to determine the characteristics associated with rodent consumption and related behaviors among different ethnic groups, ages, and genders. Five-hundred-eighty-four (584) males and females from 18-50 years of age participated in this study. Half of them were Hmong (292, 50%) while 152 respondents were Lao-Tai (26%) or other ethnic groups (140, 24%). Most of the respondents (79.5%) had farming as their main occupation. Prevalences of the studied outcomes were high: 39.9 for hunting or capturing rodents in the previous year, 77.7% for preparing rodents as food, and 86.3% for rodent consumption. Multivariable logistic regression analysis showed that likelihood of these types of rodent contact was more consistently associated with behavioral factors (gathering things from the forest and elsewhere, cultivation-related activities, and taking measures to prevent rodent-borne disease) than with socio-demographic, environmental, or cultural factors. The strongest associations were observed for gathering things; these associations were consistently positive and statistically significant. Although this study did not directly assess rodent-borne zoonosis risk, we believe that study findings raise concern that such risk may be substantial in the study area and other similar areas. Further epidemiological studies on the association between rodent-borne disease infection and rodent hunting, preparation for food, and consumption are recommended. Moreover, further studies are needed on the association between these potential exposure factors (i.e., rodent hunting, preparation for food, and consumption) and rodent-borne infections, especially among ethnic groups like the Hmong in Lao PDR and those in neighboring countries with similar socio-demographic, environmental, behavioral and cultural contexts.

  8. Arenavirus Diversity and Phylogeography of Mastomys natalensis Rodents, Nigeria

    PubMed Central

    Obadare, Adeoba; Oyeyiola, Akinlabi; Igbokwe, Joseph; Fasogbon, Ayobami; Igbahenah, Felix; Ortsega, Daniel; Asogun, Danny; Umeh, Prince; Vakkai, Innocent; Abejegah, Chukwuyem; Pahlman, Meike; Becker-Ziaja, Beate; Günther, Stephan; Fichet-Calvet, Elisabeth

    2016-01-01

    Mastomys natalensis rodents are natural hosts for Lassa virus (LASV). Detection of LASV in 2 mitochondrial phylogroups of the rodent near the Niger and Benue Rivers in Nigeria underlines the potential for LASV emergence in fresh phylogroups of this rodent. A Mobala-like sequence was also detected in eastern Nigeria. PMID:26982388

  9. A Field Study of Plague and Tularemia in Rodents, Western Iran.

    PubMed

    Mostafavi, Ehsan; Shahraki, Abdolrazagh Hashemi; Japoni-Nejad, Alireza; Esmaeili, Saber; Darvish, Jamshid; Sedaghat, Mohammad Mehdi; Mohammadi, Ali; Mohammadi, Zeinolabedin; Mahmoudi, Ahmad; Pourhossein, Behzad; Ghasemi, Ahmad; Gyuranecz, Miklós; Carniel, Elisabeth

    2017-04-01

    Kurdistan Province in Iran is a historical focus for plague and tularemia. This study aimed at assessing the current status of these two foci by studying their rodent reservoirs. Rodents were trapped and their ectoparasites were collected. The genus and species of both rodents and ectoparasites were determined. Serological analyses of rodent blood samples were done by enzyme-linked immunosorbent assay for plague and by standard tube agglutination assay for tularemia. Rodent spleen samples were subjected to bacterial culture, microscopic examination, and real-time PCR to search for active plague or tularemia infection. During this study, 245 rodents were trapped, of which the most abundant genera were Apodemus (40%), Mus (24.49%), and Meriones (12.65%). One hundred fifty-three fleas, 37 mites, and 54 ticks were collected on these rodents. The results of all direct and indirect tests were negative for plague. Serological tests were positive for tularemia in 4.8% of trapped rodents. This study is the first report on the presence of tularemia infection in rodents in Western Iran. Since Meriones persicus is a known reservoir for plague and tularemia, and this rodent carried plague and tularemia vectors in Marivan and Sanandaj districts, there is a real potential for the occurrence of these two diseases in this region.

  10. 11. BUOY DECK, NEAR PILOT HOUSE SUPERSTRUCTURE, LOOKING TOWARDS HATCH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. BUOY DECK, NEAR PILOT HOUSE SUPERSTRUCTURE, LOOKING TOWARDS HATCH DOOR INTO WINCH ROOM IN THE SUPERSTRUCTURE (LABELED AS FASSAGE & HYDRAULIC MACHINERY ON PLAN), SHOWING UNDERSIDE OF GEARED WHEEL OF BOOM. - U.S. Coast Guard Cutter WHITE LUPINE, U.S. Coast Guard Station Rockland, east end of Tillson Avenue, Rockland, Knox County, ME

  11. 5. VIEW OF VENTILATION HOUSES AND ROOF MONITOR FROM SOUTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. VIEW OF VENTILATION HOUSES AND ROOF MONITOR FROM SOUTHEAST CORNER OF ROOF. ROOF MONITOR WINDOWS HAVE BEEN INFILLED WITH BRICK. THE VENTILATION HOUSES ARE PART OF THE ORIGINAL CENTRAL AIR CONDITIONING SYSTEM AND CONTAINED AIR WASHERS, FANS AND OTHER HUMIDFYING EQUIPMENT FROM PARKS-CRAMER COMPANY OF FITCHBURG, MASSACHUSETTS. LOCATING THIS EQUIPMENT ON THE ROOF MADE IT UNNECESSARY TO CONSTRUCT A FULL BASEMENT, AND THEREFORE LOWERED CONSTRUCTION COSTS. THIS ARRANGEMENT ALSO PUT THE AIR CONDITIONING EQUIPMENT CLOSEST TO THE TOP FLOOR SPINNING ROOM, WHICH HAD THE GREATEST COOLING REQUIREMENTS. - Stark Mill, 117 Corinth Road, Hogansville, Troup County, GA

  12. Dim light at night increases immune function in Nile grass rats, a diurnal rodent.

    PubMed

    Fonken, Laura K; Haim, Achikam; Nelson, Randy J

    2012-02-01

    With the widespread adoption of electrical lighting during the 20th century, human and nonhuman animals became exposed to high levels of light at night for the first time in evolutionary history. This divergence from the natural environment may have significant implications for certain ecological niches because of the important influence light exerts on the circadian system. For example, circadian disruption and nighttime light exposure are linked to changes in immune function. The majority of studies investigating the effects of light exposure and circadian disruption on the immune system use nocturnal rodents. In diurnal species, many hormones and immune parameters vary with secretion patterns 180° out of phase to those of nocturnal rodents. Thus, the authors investigated the effects of nighttime light exposure on immunocompetence in diurnal Nile grass rats (Arvicanthis niloticus). Rats were housed in either standard 14-h light (L):10-h dark (D) cycles with L ∼150 lux and D 0 lux or dim light at night (dLAN) cycles of LD 14:10 with L ∼150 lux and D 5 lux for 3 wks, then tested for plasma bactericidal capacity, as well as humoral and cell-mediated immune responses. Rats exposed to dLAN showed increased delayed-type hypersensitivity pinna swelling, which is consistent with enhanced cell-mediated immune function. dLAN rats similarly showed increased antibody production following inoculation with keyhole lymphocyte hemocyanin (KLH) and increased bactericidal capacity. Daytime corticosterone concentrations were elevated in grass rats exposed to nighttime dim light, which may have influenced immunological measures. Overall, these results indicate nighttime light affects immune parameters in a diurnal rodent.

  13. Relationships between 222Rn dissolved in ground water supplies and indoor 222Rn concentrations in some Colorado front range houses

    USGS Publications Warehouse

    Folger, P.F.; Nyberg, P.; Wanty, R.B.; Poeter, E.

    1994-01-01

    Indoor 222Rn concentrations were measured in 37 houses with alpha track detectors placed in water-use rooms near water sources (bathrooms, laundry rooms, and kitchens) and in non-water-use living rooms, dining rooms, and bedrooms away from water sources. Results show that relative contributions of 222Rn to indoor air from water use are insignificant when soil-gas concentrations are high but become increasingly important as the ratio of 222Rn-in-water:222Rn-in-soil gas increases. High soil-gas 222Rn concentrations may mask 222Rn contributions from water even when waterborne 222Rn concentrations are as high as 750 kBq m-3. Ground water in Precambrian Pikes Peak granite averages 340 kBq m-3222Rn, vs. 170 kBq m-3 in Precambrian migmatite, but average 222Rn concentrations in soil gas are also lower in migmatite. Because the ratio of 222Rn-in- water:222Rn-in-soil gas may be consistently higher for houses in migmatite than in Pikes Peak granite, indoor air in houses built on migmatite may have a greater relative contribution from water use even though average 222Rn concentrations in the water are lower. Continuous monitoring of 222Rn concentrations in air on 15-min intervals also indicates that additions to indoor concentrations from water use are significant and measurable only when soil-gas concentrations are low and concentrations in water are high. When soil-gas concentrations were mitigated to less than 150 Bq m-3 in one house, water contributes 20-40% of the annual indoor 222Rn concentration in the laundry room (222Rn concentration in water of 670 kBq m-3). Conversely, when the mitigation system is inactive, diurnal fluctuations and other variations in the soil-gas 222Rn contribution swamp the variability due to water use in the house. Measurable variations in indoor concentrations from water use were not detected in one house despite a low soil-gas contribution of approximately 150 Bq m-3 because waterborne 222Rn concentrations also are low (80 kBq m-3). This

  14. Teaching medicine with the help of "Dr. House".

    PubMed

    Jerrentrup, Andreas; Mueller, Tobias; Glowalla, Ulrich; Herder, Meike; Henrichs, Nadine; Neubauer, Andreas; Schaefer, Juergen R

    2018-01-01

    TV series such as "House MD", "Grey´s Anatomy" or "Emergency Room" are well perceived by medical students. Seminars featuring medical TV series such as "House MD" might serve as door-opener to attract medical students to learn more about rare diseases. The TV series "House MD" is troublesome for the main character Dr. House is an excellent diagnostician but at the same time a rather misanthropic person. Therefore, lecturing medicine with the help of "House MD" requires constant evaluation. From 2008 to 2016 we are using the well-known TV series "House MD" continuously to attract medical students and teach them about rare diseases as well as diagnostic strategies. We collected from 213 students a detailed questionnaire assessing their learning experience. 76.6% of our students (n = 157) reported to watching medical dramas on a regular basis. The Dr. House seminar was compared to traditional seminars and our students reported an improved learning effect (69.9%), better concentration (89.7%), higher motivation to participate (88.7%), and more fun (86.7%) (all p<0.001). The students see Dr. House's behavior quite critically. Likert assessment on a 5-point scale identified strong disagreement with Dr. House´s interpersonal skills in dealing with his colleagues (median = 1) and patients (median = 1). At the same time, the students strongly agreed with his outstanding diagnostic (median = 5) and therapeutic capabilities (median = 4). Medical students visiting a Dr. House teaching seminar are highly motivated to learn more about rare diseases. They were positively influenced by TV series such as Dr. House to improve their diagnostic and clinical skills. At the same time, they are critical enough not to see Dr. House as a role model for their own personality. Well performed medical TV shows such as Dr. House can successfully be used in an educational setting to motivate medical students to come into seminars to learn more about rare diseases.

  15. Comparison of two whole-room ultraviolet irradiation systems for enhanced disinfection of contaminated hospital patient rooms.

    PubMed

    Ali, S; Yui, S; Muzslay, M; Wilson, A P R

    2017-10-01

    Ultraviolet (UV) light decontamination systems are being used increasingly to supplement terminal disinfection of patient rooms. However, efficacy may not be consistent in the presence of soil, especially against Clostridium difficile spores. To demonstrate in-use efficacy of two whole-room UV decontamination systems against three hospital pathogens with and without soil. For each system, six patient rooms were decontaminated with UV irradiation (enhanced disinfection) following manual terminal cleaning. Total aerobic colony counts of surface contamination were determined by spot-sampling 15 environmental sites before and after terminal disinfection and after UV irradiation. Efficacy against biological indicator coupons (stainless-steel discs) was performed for each system using test bacteria (10 6  cfu EMRSA-15 variant A, carbapenemase-producing Klebsiella pneumoniae) or spores (10 5  cfu C. difficile 027), incorporating low soiling [0.03% bovine serum albumin (BSA)], heavy soiling (10% BSA) or synthetic faeces (C. difficile only) placed at five locations in the room. UV disinfection eliminated contamination after terminal cleaning in 8/14 (57%) and 11/14 (79%) sites. Both systems demonstrated 4-5 log 10 reductions in meticillin-resistant Staphylococcus aureus and K. pneumoniae at low soiling. Lower and more variable log 10 reductions were achieved when heavy soiling was present. Between 0.1 and 4.8 log 10 reductions in C. difficile spores were achieved with low but not heavy soil challenge. Terminal disinfection should be performed on all surfaces prior to UV decontamination. In-house validation studies should be considered to ensure optimal positioning in each room layout and sufficient cycle duration to eliminate target pathogens. Copyright © 2017 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

  16. Associations of Poor Housing with Mental Health Among North Carolina Latino Migrant Farmworkers.

    PubMed

    Mora, Dana C; Quandt, Sara A; Chen, Haiying; Arcury, Thomas A

    2016-01-01

    This analysis examines the associations of housing conditions with mental health among migrant farmworkers. Data are from a 2010 cross-sectional study conducted in 16 North Carolina counties. Interviews and housing inspections were completed with 371 farmworkers in 186 camps. Mental health measures included depression (Center for Epidemiologic Studies Depression Scale, CES-D), anxiety (Personality Assessment Inventory, PAI), and alcohol misuse (Alcohol Use Disorders Identification Test, AUDIT-C). Housing measures were number of people per sleeping room, perceived security of self and belongings, having a key to dwelling's door, having bedroom storage, toilet privacy issues, and number of housing regulation violations. Sixty (16.7%) participants had substantial depressive symptoms (CES-D ≥10), 31 (8.8%) had substantial anxiety (PAI ≥27), and 185 (50.1%) had the potential for alcohol misuse (AUDIT-C ≥4). Those with 5+ persons sleeping per room were more likely to have a depression score ≥10 (31.5% vs. 13-14%, P = .01) and an anxiety scores ≥27 (19.6% vs. 5-9%, P = .02). Those who did not feel they or their belongings were secure were more likely to have a depression score ≥10 (19.4% vs. 9.1%, P = .01). Those without a key were more likely to have an anxiety score ≥27 (11.5% vs. 5.1%, P = .04). Those with no bedroom storage were more likely to have a depression score ≥10 (28.9% vs. 14.9%, P = .03). This article suggests links between poor housing and farmworkers' mental health. These results inform regulations surrounding farmworker housing and inform health care providers on how to prevent and treat poor mental health among migrant farmworkers.

  17. Reproductive changes in fluctuating house mouse populations in southeastern Australia.

    PubMed

    Singleton, G; Krebs, C J; Davis, S; Chambers, L; Brown, P

    2001-08-22

    House mice (Mus domesticus) in the Victorian mallee region of southeastern Australia show irregular outbreaks. Changes in reproductive output that could potentially drive changes in mouse numbers were assessed from 1982 to 2000. Litter size in females is positively correlated with body size. When standardized to an average size female, litter size changes seasonally from highest in spring to lowest in autumn and winter. Litter size is depressed throughout breeding seasons that begin when the abundance of mice is high, but is similar in breeding seasons over which the abundance of mice increases rapidly or remains low. Breeding begins early and is extended on average by about five weeks during seasons when mouse abundance increases rapidly. The size at which females begin to reproduce is larger during breeding seasons that begin when mouse abundance is high. An extended breeding season that begins early in spring is necessary for the generation of a house mouse plague, but it is not in itself sufficient. Reproductive changes in outbreaks of house mice in Australia are similar but not identical to reproductive changes that accompany rodent population increases in the Northern Hemisphere. We conclude that food quality, particularly protein, is a probable mechanism driving these reproductive changes, but experimental evidence for field populations is conflicting.

  18. A novel dietary restriction method for group-housed rats: weight gain and clinical chemistry characterization.

    PubMed

    Kasanen, I H E; Inhilä, K J; Nevalainen, J I; Väisänen, S B; Mertanen, A M O; Mering, S M; Nevalainen, T O

    2009-04-01

    Laboratory rodents are usually fed ad libitum. Moderate dietary restriction decreases mortality and morbidity compared with ad libitum feeding. There are, however, problems in achieving dietary restriction. Traditional methods of restricted feeding may interfere with the diurnal rhythms of the animals and are not compatible with group-housing of rodents. We have invented a novel method, the diet board, for restricting the feed intake of laboratory rats. The use of the diet board moderately decreased weight gain of rats when compared with ad libitum-fed animals. The diet board retarded skeletal growth only minimally, whereas major differences were found in body fat depositions. Serum free fatty acid, triglyceride and cholesterol values were lower in diet-restricted rats, while the opposite was true for serum creatine kinase. There were no differences in total protein, albumin or alanine aminotransferase. Moreover, differences in interindividual variances in parameters were not detected between the groups; hence this study could not combine the diet board with reduction potential. The diet board provides mild to moderate dietary restriction for group-housed rats and is unlikely to interfere with the diurnal eating rhythm. The diet board can also be seen as a cage furniture item, dividing the open cage space and increasing the structural complexity of the environment. In conclusion, the diet board appears to possess refinement potential when compared with traditional methods of dietary restriction.

  19. 13. CELLAR, UNDER MAIN MEETING ROOM, LOOKING NORTH. The 1909 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. CELLAR, UNDER MAIN MEETING ROOM, LOOKING NORTH. The 1909 hot air furnace with brick wall enclosure of possibly earlier origin. A hot air system of two furnaces was installed with ventilating ducts in the east end in 1852. There was a hot air system in the west end without ventilating ducts. - Twelfth Street Meeting House, 20 South Twelfth Street, Philadelphia, Philadelphia County, PA

  20. 6. INTERIOR OF LIVING ROOM SHOWING OPEN DOORWAY TO KITCHEN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. INTERIOR OF LIVING ROOM SHOWING OPEN DOORWAY TO KITCHEN AT PHOTO CENTER, FLUSH FRONT DOOR WITH GLAZING AT PHOTO RIGHT, AND OPEN PANELED DOOR TO BEDROOM NO. 2 AT LEFT PHOTO CENTER. DECORATIVE WOOD STRIPPING ON WALLS AND CEILING IS CARRIED THROUGHOUT REST OF ORIGINAL PORTION OF HOUSE. VIEW TO NORTH. - Bishop Creek Hydroelectric System, Plant 4, Worker Cottage, Bishop Creek, Bishop, Inyo County, CA

  1. Identification of novel anelloviruses with broad diversity in UK rodents

    PubMed Central

    Nishiyama, Shoko; Dutia, Bernadette M.; Stewart, James P.; Meredith, Anna L.; Shaw, Darren J.; Simmonds, Peter

    2014-01-01

    Anelloviruses are a family of small circular ssDNA viruses with a vast genetic diversity. Human infections with the prototype anellovirus, torque teno virus (TTV), are ubiquitous and related viruses have been described in a number of other mammalian hosts. Despite over 15 years of investigation, there is still little known about the pathogenesis and possible disease associations of anellovirus infections, arising in part due to the lack of a robust cell culture system for viral replication or tractable small-animal model. We report the identification of diverse anelloviruses in several species of wild rodents. The viruses are highly prevalent in wood mice (Apodemus sylvaticus) and field voles (Microtus agrestis), detectable at a low frequency in bank voles (Myodes glareolus), but absent from house mice (Mus musculus). The viruses identified have a genomic organization consistent with other anelloviruses, but form two clear phylogenetic groups that are as distinct from each other as from defined genera. PMID:24744300

  2. Experimental encephalomyocarditis virus infection in small laboratory rodents.

    PubMed

    Doi, K

    2011-01-01

    Encephalomyocarditis virus (EMCV) is a cardiovirus that belongs to the family Picornaviridae. EMCV is an important cause of acute myocarditis in piglets and of fetal death or abortion in pregnant sows. Small rodents, especially rats, have been suspected to be reservoir hosts or carriers. This virus also induces type 1 diabetes mellitus, encephalomyelitis, myocarditis, orchitis and/or sialodacryoadenitis in small laboratory rodents. This paper reviews the pathology and pathogenesis of experimental infection with EMCV in small laboratory rodents. Copyright © 2010 Elsevier Ltd. All rights reserved.

  3. Emmonsiosis of rodents in an agroecosystem.

    PubMed

    Hubálek, Z; Nesvadbová, J; Halouzka, J

    1998-12-01

    Adiaspores of Emmonsia crescens were found in the lungs of 62.1% of 87 adult rodents from 10 windbreaks compared to only 8.2% of 184 adult rodents caught in 10 adjacent arable fields in South Moravia, Czechland. A significantly higher mean weight proportion of plant remnants (predominantly small roots) was present in the soil from windbreaks (0.74%) than from fields (0.24%). In addition, mean relative abundance of rodents was significantly higher in windbreaks than in fields, and the windbreak soil was more acidic (pH 6.2 vs. 6.9, respectively). On the other hand, there was no significant difference in the water content (17.4% vs. 18.5%, respectively). The difference in the infection rate between the two habitats of the agroecosystem could be caused or affected by land use and farming technology.

  4. Enamel mineral concentration in diabetic rodents.

    PubMed

    Atar, M; Davis, G R; Verry, P; Wong, F S L

    2007-12-01

    This was to use x-ray microtomography (XMT), to assess the mineral composition and 3-D structure of enamel and bone in the teeth and skulls of diabetic rodents. Three-dimensional images of the skull were reconstructed using computer generated false colour to highlight different levels of mineralization in bone and enamel. These showed that diabetic rodents exhibited more wear in their teeth. Deformities were observed in the alveolar process of the mandible and maxilla. Regions of extensive hypomineralization were found in the calvarial bone of skulls. The maximum mineral concentrations and the time constants for diabetic rodents were similar to the controls. The diabetic mice appeared to have random regions of hypomineralization and one diabetic rat had areas of hypoplasia in the mandibular incisors. Diabetes may have a detrimental influence on the function of ameloblasts in laying down enamel.

  5. Can a native rodent species limit the invasive potential of a non-native rodent species in tropical agroforest habitats?

    PubMed

    Stuart, Alexander M; Prescott, Colin V; Singleton, Grant R

    2016-06-01

    Little is known about native and non-native rodent species interactions in complex tropical agroecosystems. We hypothesised that the native non-pest rodent Rattus everetti may be competitively dominant over the invasive pest rodent Rattus tanezumi within agroforests. We tested this experimentally by using pulse removal for three consecutive months to reduce populations of R. everetti in agroforest habitat, and assessed over 6 months the response of R. tanezumi and other rodent species. Following removal, R. everetti individuals rapidly immigrated into removal sites. At the end of the study period, R. tanezumi were larger and there was a significant shift in their microhabitat use with respect to the use of ground vegetation cover following the perturbation of R. everetti. Irrespective of treatment, R. tanezumi selected microhabitat with less tree canopy cover, indicative of severely disturbed habitat, whereas R. everetti selected microhabitat with a dense canopy. Our results suggest that sustained habitat disturbance in agroforests favours R. tanezumi, while the regeneration of agroforests towards a more natural state would favour native species and may reduce pest pressure in adjacent crops. In addition, the rapid recolonisation of R. everetti suggests this species would be able to recover from non-target impacts of short-term rodent pest control. © 2015 Society of Chemical Industry. © 2015 Society of Chemical Industry.

  6. Testing the limits of Rodent Sperm Analysis: azoospermia in an otherwise healthy wild rodent population.

    PubMed

    Tannenbaum, Lawrence V; Thran, Brandolyn H; Willams, Keith J

    2009-01-01

    By comparing the sperm parameters of small rodents trapped at contaminated terrestrial sites and nearby habitat-matched noncontaminated locations, the patent-pending Rodent Sperm Analysis (RSA) method provides a direct health status appraisal for the maximally chemical-exposed mammalian ecological receptor in the wild. RSA outcomes have consistently allowed for as definitive determinations of receptor health as are possible at the present time, thereby streamlining the ecological risk assessment (ERA) process. Here, we describe the unanticipated discovery, at a contaminated US EPA Superfund National Priorities List site, of a population of Hispid cotton rats (Sigmodon hispidus), with a high percentage of adult males lacking sperm entirely (azoospermia). In light of the RSA method's role in streamlining ERAs and in bringing contaminated Superfund-type site investigations to closure, we consider the consequences of the discovery. The two matters specifically discussed are (1) the computation of a population's average sperm count where azoospermia is present and (2) the merits of the RSA method and its sperm parameter thresholds-for-effect when azoospermia is masked in an otherwise apparently healthy rodent population.

  7. Competition between harvester ants and rodents in the cold desert

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Landeen, D.S.; Jorgensen, C.D.; Smith, H.D.

    1979-09-30

    Local distribution patterns of three rodent species (Perognathus parvus, Peromyscus maniculatus, Reithrodontomys megalotis) were studied in areas of high and low densities of harvester ants (Pogonomyrmex owyheei) in Raft River Valley, Idaho. Numbers of rodents were greatest in areas of high ant-density during May, but partially reduced in August; whereas, the trend was reversed in areas of low ant-density. Seed abundance was probably not the factor limiting changes in rodent populations, because seed densities of annual plants were always greater in areas of high ant-density. Differences in seasonal population distributions of rodents between areas of high and low ant-densities weremore » probably due to interactions of seed availability, rodent energetics, and predation.« less

  8. Old World Hantaviruses in Rodents in New Orleans, Louisiana

    PubMed Central

    Cross, Robert W.; Waffa, Bradley; Freeman, Ashley; Riegel, Claudia; Moses, Lina M.; Bennett, Andrew; Safronetz, David; Fischer, Elizabeth R.; Feldmann, Heinz; Voss, Thomas G.; Bausch, Daniel G.

    2014-01-01

    Seoul virus, an Old World hantavirus, is maintained in brown rats and causes a mild form of hemorrhagic fever with renal syndrome (HFRS) in humans. We captured rodents in New Orleans, Louisiana and tested them for the presence of Old World hantaviruses by reverse transcription polymerase chain reaction (RT-PCR) with sequencing, cell culture, and electron microscopy; 6 (3.4%) of 178 rodents captured—all brown rats—were positive for a Seoul virus variant previously coined Tchoupitoulas virus, which was noted in rodents in New Orleans in the 1980s. The finding of Tchoupitoulas virus in New Orleans over 25 years since its first discovery suggests stable endemicity in the city. Although the degree to which this virus causes human infection and disease remains unknown, repeated demonstration of Seoul virus in rodent populations, recent cases of laboratory-confirmed HFRS in some US cities, and a possible link with hypertensive renal disease warrant additional investigation in both rodents and humans. PMID:24639295

  9. Old World hantaviruses in rodents in New Orleans, Louisiana.

    PubMed

    Cross, Robert W; Waffa, Bradley; Freeman, Ashley; Riegel, Claudia; Moses, Lina M; Bennett, Andrew; Safronetz, David; Fischer, Elizabeth R; Feldmann, Heinz; Voss, Thomas G; Bausch, Daniel G

    2014-05-01

    Seoul virus, an Old World hantavirus, is maintained in brown rats and causes a mild form of hemorrhagic fever with renal syndrome (HFRS) in humans. We captured rodents in New Orleans, Louisiana and tested them for the presence of Old World hantaviruses by reverse transcription polymerase chain reaction (RT-PCR) with sequencing, cell culture, and electron microscopy; 6 (3.4%) of 178 rodents captured--all brown rats--were positive for a Seoul virus variant previously coined Tchoupitoulas virus, which was noted in rodents in New Orleans in the 1980s. The finding of Tchoupitoulas virus in New Orleans over 25 years since its first discovery suggests stable endemicity in the city. Although the degree to which this virus causes human infection and disease remains unknown, repeated demonstration of Seoul virus in rodent populations, recent cases of laboratory-confirmed HFRS in some US cities, and a possible link with hypertensive renal disease warrant additional investigation in both rodents and humans.

  10. Ground-based rodent control in a remote Hawaiian rainforest on Maui

    USGS Publications Warehouse

    Malcolm, T.R.; Swinnerton, K.J.; Groombridge, J.J.; Sparklin, B.D.; Brosius, C.N.; Vetter, J.P.; Foster, J.T.

    2008-01-01

    Effective control of introduced mammalian predators is essential to the recovery of native bird species in Hawai'i. Between August 1996 and December 2004, introduced rodents were controlled within three home ranges of the Po'ouli Melamprosops phaeosoma, a critically endangered Hawaiian honeycreeper. Rats were controlled using a combination of ground-based rodenticide (0.005% diphacinone) application and snap traps. Beginning in August 2001, we monitored the effectiveness of these rodent control efforts. Relative abundances of Black Rats Rattus rattus and Polynesian Rats R. exulans were measured in each of five snap-trapping grids seven times over a 35-month period. Rat populations decreased inside of the rodent control areas, but control effectiveness differed between rat species. During the first year of monitoring, target control levels for R. rattus were consistently achieved in only one of the rodent control areas. Control techniques were refined in areas failing to meet targets. Subsequently, we achieved target control levels for R. rattus more consistently in all three rodent control areas. However, relative abundances of R. exulans did not differ between rodent control and reference areas, indicating that our rodent control techniques were insufficient to reduce population levels of this species. These findings signify a need for further improvement of rodent control methods in Hawai'i, especially for Polynesian Rats, and demonstrate the critical importance of periodic monitoring of the response of rodent populations to management. In the future, managers may need to design rodent control operations targeting R. rattus and R. exulans independently to achieve best results.

  11. A SPECT Scanner for Rodent Imaging Based on Small-Area Gamma Cameras

    NASA Astrophysics Data System (ADS)

    Lage, Eduardo; Villena, José L.; Tapias, Gustavo; Martinez, Naira P.; Soto-Montenegro, Maria L.; Abella, Mónica; Sisniega, Alejandro; Pino, Francisco; Ros, Domènec; Pavia, Javier; Desco, Manuel; Vaquero, Juan J.

    2010-10-01

    We developed a cost-effective SPECT scanner prototype (rSPECT) for in vivo imaging of rodents based on small-area gamma cameras. Each detector consists of a position-sensitive photomultiplier tube (PS-PMT) coupled to a 30 x 30 Nal(Tl) scintillator array and electronics attached to the PS-PMT sockets for adapting the detector signals to an in-house developed data acquisition system. The detector components are enclosed in a lead-shielded case with a receptacle to insert the collimators. System performance was assessed using 99mTc for a high-resolution parallel-hole collimator, and for a 0.75-mm pinhole collimator with a 60° aperture angle and a 42-mm collimator length. The energy resolution is about 10.7% of the photopeak energy. The overall system sensitivity is about 3 cps/μCi/detector and planar spatial resolution ranges from 2.4 mm at 1 cm source-to-collimator distance to 4.1 mm at 4.5 cm with parallel-hole collimators. With pinhole collimators planar spatial resolution ranges from 1.2 mm at 1 cm source-to-collimator distance to 2.4 mm at 4.5 cm; sensitivity at these distances ranges from 2.8 to 0.5 cps/μCi/detector. Tomographic hot-rod phantom images are presented together with images of bone, myocardium and brain of living rodents to demonstrate the feasibility of preclinical small-animal studies with the rSPECT.

  12. Individual housing-based socioeconomic status predicts risk of accidental falls among adults.

    PubMed

    Ryu, Euijung; Juhn, Young J; Wheeler, Philip H; Hathcock, Matthew A; Wi, Chung-Il; Olson, Janet E; Cerhan, James R; Takahashi, Paul Y

    2017-07-01

    Accidental falls are a major public health concern among people of all ages. Little is known about whether an individual-level housing-based socioeconomic status measure is associated with the risk of accidental falls. Among 12,286 Mayo Clinic Biobank participants residing in Olmsted County, Minnesota, subjects who experienced accidental falls between the biobank enrollment and September 2014 were identified using ICD-9 codes evaluated at emergency departments. HOUSES (HOUsing-based Index of SocioEconomic Status), a socioeconomic status measure based on individual housing features, was also calculated. Cox regression models were utilized to assess the association of the HOUSES (in quartiles) with accidental fall risk. Seven hundred eleven (5.8%) participants had at least one emergency room visit due to an accidental fall during the study period. Subjects with higher HOUSES were less likely to experience falls in a dose-response manner (hazard ratio: 0.58; 95% confidence interval: 0.44-0.76 for comparing the highest to the lowest quartile). In addition, the HOUSES was positively associated with better health behaviors, social support, and functional status. The HOUSES is inversely associated with accidental fall risk requiring emergency care in a dose-response manner. The HOUSES may capture falls-related risk factors through housing features and socioeconomic status-related psychosocial factors. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Lassa fever or lassa hemorrhagic fever risk to humans from rodent-borne zoonoses.

    PubMed

    El-Bahnasawy, Mamdouh M; Megahed, Laila Abdel-Mawla; Abdalla Saleh, Hala Ahmed; Morsy, Tosson A

    2015-04-01

    Viral hemorrhagic fevers (VHFs) typically manifest as rapidly progressing acute febrile syndromes with profound hemorrhagic manifestations and very high fatality rates. Lassa fever, an acute hemorrhagic fever characterized by fever, muscle aches, sore throat, nausea, vomiting, diarrhea and chest and abdominal pain. Rodents are important reservoirs of rodent-borne zoonosis worldwide. Transmission rodents to humans occur by aerosol spread, either from the genus Mastomys rodents' excreta (multimammate rat) or through the close contact with infected patients (nosocomial infection). Other rodents of the genera Rattus, Mus, Lemniscomys, and Praomys are incriminated rodents hosts. Now one may ask do the rodents' ectoparasites play a role in Lassa virus zoonotic transmission. This paper summarized the update knowledge on LHV; hopping it might be useful to the clinicians, nursing staff, laboratories' personals as well as those concerned zoonoses from rodents and rodent control.

  14. Rodent-associated Bartonella Febrile Illness, Southwestern United States

    PubMed Central

    Iralu, Jonathan; Bai, Ying; Crook, Larry; Tempest, Bruce; Simpson, Gary; McKenzie, Taylor

    2006-01-01

    Serum specimens from 114 patients hospitalized with a febrile illness were tested with an indirect immunofluorescence assay (IFA) using Bartonella antigens prepared from 6 species of sigmodontine rodents and 3 known human Bartonella pathogens: B. henselae, B. quintana, and B. elizabethae. Acute- and convalescent-phase serum samples from 5 of these patients showed seroconversion with an IFA titer >512 to rodent-associated Bartonella antigens. The highest titer was against antigen derived from the white-throated woodrat (Neotoma albigula), although this rodent is not necessarily implicated as the source of infection. Three of the 5 who seroconverted showed no cross-reaction to the 3 Bartonella human pathogens. Common clinical characteristics were fever, chills, myalgias, leukopenia, thrombocytopenia, and transaminasemia. Although antibodies to Bartonella are cross-reactive, high-titer seroconversions to rodent-associated Bartonella antigens in adults with common clinical characteristics should stimulate the search for additional Bartonella human pathogens. PMID:16836824

  15. Problems associated with the control of rodents in tropical Africa

    PubMed Central

    Gratz, N. G.; Arata, A. A.

    1975-01-01

    As elsewhere in the world, rodents are responsible for very considerable economic losses in tropical Africa because of their depredations on both growing crops and stored food products. Unfortunately, few accurate data are available on the extent of these losses but there is evidence that they are considerable. The public health importance of rodents, both as reservoirs and vectors of disease in tropical Africa, is also great; plague, leptospirosis, murine typhus, and Lassa fever are among the diseases associated with rodent hosts. Scientifically based rodent control programmes have been carried out in very few areas of Africa and there is urgent need for studies and demonstrations on rodent control in both urban and rural areas. The problems likely to be encountered are reviewed and methods of control proposed. PMID:1085224

  16. 4. Log chicken house (far left foreground), log bunkhouse (far ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Log chicken house (far left foreground), log bunkhouse (far left background), one-room log cabin (left of center background), log root cellar (center), post-and-beam center in foreground, and blacksmith shop (far right foreground). View to southeast. - William & Lucina Bowe Ranch, County Road 44, 0.1 mile northeast of Big Hole River Bridge, Melrose, Silver Bow County, MT

  17. Repeated evolution of carnivory among Indo-Australian rodents.

    PubMed

    Rowe, Kevin C; Achmadi, Anang S; Esselstyn, Jacob A

    2016-03-01

    Convergent evolution, often observed in island archipelagos, provides compelling evidence for the importance of natural selection as a generator of species and ecological diversity. The Indo-Australian Archipelago (IAA) is the world's largest island system and encompasses distinct biogeographic units, including the Asian (Sunda) and Australian (Sahul) continental shelves, which together bracket the oceanic archipelagos of the Philippines and Wallacea. Each of these biogeographic units houses numerous endemic rodents in the family Muridae. Carnivorous murids, that is those that feed on animals, have evolved independently in Sunda, Sulawesi (part of Wallacea), the Philippines, and Sahul, but the number of origins of carnivory among IAA murids is unknown. We conducted a comprehensive phylogenetic analysis of carnivorous murids of the IAA, combined with estimates of ancestral states for broad diet categories (herbivore, omnivore, and carnivore) and geographic ranges. These analyses demonstrate that carnivory evolved independently four times after overwater colonization, including in situ origins on the Philippines, Sulawesi, and Sahul. In each biogeographic unit the origin of carnivory was followed by evolution of more specialized carnivorous ecomorphs such as vermivores, insectivores, and amphibious rats. © 2016 The Author(s). Evolution © 2016 The Society for the Study of Evolution.

  18. Rodent analgesia: Assessment and therapeutics.

    PubMed

    Flecknell, Paul

    2018-02-01

    Current use of analgesics to control procedure-related pain in laboratory rodents is unacceptably low. Almost all currently available analgesics were developed in small rodents, prior to use in man, so that safety and efficacy data in laboratory assays are available. Greater use of analgesics would be encouraged by critical evaluation of the potential interactions of these compounds with the outcomes of specific research studies. As in other species, effective post-procedural analgesia requires reliable 'cage-side' methods of assessing pain. Recent advances in pain assessment should lead to both more extensive and more effective use of analgesics in these species. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Resident outcomes in small-house nursing homes: a longitudinal evaluation of the initial green house program.

    PubMed

    Kane, Rosalie A; Lum, Terry Y; Cutler, Lois J; Degenholtz, Howard B; Yu, Tzy-Chyi

    2007-06-01

    To determine the effects of a small-house nursing home model, THE GREEN HOUSE (GH), on residents' reported outcomes and quality of care. Two-year longitudinal quasi-experimental study comparing GH residents with residents at two comparison sites using data collected at baseline and three follow-up intervals. Four 10-person GHs, the sponsoring nursing home for those GHs, and a traditional nursing home with the same owner. All residents in the GHs (40 at any time) at baseline and three 6-month follow-up intervals, and 40 randomly selected residents in each of the two comparison groups. The GH alters the physical scale environment (small-scale, private rooms and bathrooms, residential kitchen, dining room, and hearth), the staffing model for professional and certified nursing assistants, and the philosophy of care. Scales for 11 domains of resident quality of life, emotional well-being, satisfaction, self-reported health, and functional status were derived from interviews at four points in time. Quality of care was measured using indicators derived from Minimum Data Set assessments. Controlling for baseline characteristics (age, sex, activities of daily living, date of admission, and proxy interview status), statistically significant differences in self-reported dimensions of quality of life favored the GHs over one or both comparison groups. The quality of care in the GHs at least equaled, and for change in functional status exceeded, the comparison nursing homes. The GH is a promising model to improve quality of life for nursing home residents, with implications for staff development and medical director roles.

  20. Results from a Survey of Current Practices for Sampling of Nervous System in Rodents and Non-rodents in General Toxicity Studies

    EPA Science Inventory

    A survey of current practices for sampling and examination of the nervous system in rodents and non-rodents for general and neurotoxicity (NT) studies was conducted by the Nervous System Sampling Subcommittee of the STP. For general toxicity studies most of those surveyed (>63%) ...

  1. Behavior and Welfare of Domestic Cats Housed in Cages Larger than U.S. Norm.

    PubMed

    Stella, Judith L; Croney, Candace C; Buffington, C Tony

    2017-01-01

    The effect of providing additional floor space on cat behavior and welfare is not well documented. This study involved replication of an investigation of cats' responses to enhanced cage and room environments using cages of 0.56 m 2 with the same methodology but an increased space allowance of 1.1 m 2 . Singly housed adult cats (n = 59) were randomly assigned to a treatment group that was a combination of a managed or unmanaged room and an enriched or unenriched cage environment. Cats were observed for 2 days for maintenance, affiliative, and avoidant behaviors using scan sampling and 5-min, continuous focal sampling. At the end of Day 2, cats' reactions to the approach of an unfamiliar person were assessed. Cats housed in enriched/managed environments exhibited more maintenance and affiliative behaviors and fewer avoidant behaviors than cats in unmanaged/unenriched environments, suggesting that macro and micro environments may be equally relevant to the cat. Increased space did not enhance the cats' welfare outcomes, suggesting that the provision of additional cage space may not be as important to the cat as a managed housing environment.

  2. Advances in Rodent Research Missions on the International Space Station

    NASA Technical Reports Server (NTRS)

    Choi, S. Y.; Ronca, A.; Leveson-Gower, D.; Gong, C.; Stube, K.; Pletcher, D.; Wigley, C.; Beegle, J.; Globus, R. K.

    2016-01-01

    A research platform for rodent experiment on the ISS is a valuable tool for advancing biomedical research in space. Capabilities offered by the Rodent Research project developed at NASA Ames Research Center can support experiments of much longer duration on the ISS than previous experiments performed on the Space Shuttle. NASAs Rodent Research (RR)-1 mission was completed successfully and achieved a number of objectives, including validation of flight hardware, on-orbit operations, and science capabilities as well as support of a CASIS-sponsored experiment (Novartis) on muscle atrophy. Twenty C57BL6J adult female mice were launched on the Space-X (SpX) 4 Dragon vehicle, and thrived for up to 37 days in microgravity. Daily health checks of the mice were performed during the mission via downlinked video; all flight animals were healthy and displayed normal behavior, and higher levels of physical activity compared to ground controls. Behavioral analysis demonstrated that Flight and Ground Control mice exhibited the same range of behaviors, including eating, drinking, exploratory behavior, self- and allo-grooming, and social interactions indicative of healthy animals. The animals were euthanized on-orbit and select tissues were collected from some of the mice on orbit to assess the long-term sample storage capabilities of the ISS. In general, the data obtained from the flight mice were comparable to those from the three groups of control mice (baseline, vivarium and ground controls, which were housed in flight hardware), showing that the ISS has adequate capability to support long-duration rodent experiments. The team recovered 35 tissues from 40 RR-1 frozen carcasses, yielding 3300 aliquots of tissues to distribute to the scientific community in the U.S., including NASAs GeneLab project and scientists via Space Biology's Biospecimen Sharing Program Ames Life Science Data Archive. Tissues also were distributed to Russian research colleagues at the Institute for

  3. Energy Efficiency in Small Server Rooms: Field Surveys and Findings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cheung, Iris; Greenberg, Steve; Mahdavi, Roozbeh

    Fifty-seven percent of US servers are housed in server closets, server rooms, and localized data centers, in what are commonly referred to as small server rooms, which comprise 99percent of all server spaces in the US. While many mid-tier and enterprise-class data centers are owned by large corporations that consider energy efficiency a goal to minimize business operating costs, small server rooms typically are not similarly motivated. They are characterized by decentralized ownership and management and come in many configurations, which creates a unique set of efficiency challenges. To develop energy efficiency strategies for these spaces, we surveyed 30 smallmore » server rooms across eight institutions, and selected four of them for detailed assessments. The four rooms had Power Usage Effectiveness (PUE) values ranging from 1.5 to 2.1. Energy saving opportunities ranged from no- to low-cost measures such as raising cooling set points and better airflow management, to more involved but cost-effective measures including server consolidation and virtualization, and dedicated cooling with economizers. We found that inefficiencies mainly resulted from organizational rather than technical issues. Because of the inherent space and resource limitations, the most effective measure is to operate servers through energy-efficient cloud-based services or well-managed larger data centers, rather than server rooms. Backup power requirement, and IT and cooling efficiency should be evaluated to minimize energy waste in the server space. Utility programs are instrumental in raising awareness and spreading technical knowledge on server operation, and the implementation of energy efficiency measures in small server rooms.« less

  4. Enhanced magnetic Purcell effect in room-temperature masers

    PubMed Central

    Breeze, Jonathan; Tan, Ke-Jie; Richards, Benjamin; Sathian, Juna; Oxborrow, Mark; Alford, Neil McN

    2015-01-01

    Recently, the world’s first room-temperature maser was demonstrated. The maser consisted of a sapphire ring housing a crystal of pentacene-doped p-terphenyl, pumped by a pulsed rhodamine-dye laser. Stimulated emission of microwaves was aided by the high quality factor and small magnetic mode volume of the maser cavity yet the peak optical pumping power was 1.4 kW. Here we report dramatic miniaturization and 2 orders of magnitude reduction in optical pumping power for a room-temperature maser by coupling a strontium titanate resonator with the spin-polarized population inversion provided by triplet states in an optically excited pentacene-doped p-terphenyl crystal. We observe maser emission in a thimble-sized resonator using a xenon flash lamp as an optical pump source with peak optical power of 70 W. This is a significant step towards the goal of continuous maser operation. PMID:25698634

  5. 2. VIEW OF WASTE HOUSE/SECTION 16 IN FOREGROUND CENTER, WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. VIEW OF WASTE HOUSE/SECTION 16 IN FOREGROUND CENTER, WITH NAPPING BUILDING/SECTION 12 AT LEFT, CLOTH ROOM/SECTION 15 IN CENTER, SHOWING SAWTOOTH MONITOR ROOF. MILL NO. 1/SECTION 4 IS AT EXTREME RIGHT: BOOTT MILLS AND CHIMNEY IN BACKGROUND (ACROSS BRIDGE STREET), LOOKING WEST-NORTHWEST. April 1989 - Massachusetts Mills, 95 Bridge Street, Lowell, Middlesex County, MA

  6. Obama Boosts Science Education During White House Student Fair

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2010-10-01

    With the East Room of the White House flush with Nobel laureates and government officials, including freshly sworn-in U.S. National Science Foundation director Subra Suresh, President Barack Obama honored dozens of students who participated in a White House science fair on 18 October. The fair—many of whose participants have won other science, technology, engineering, and math (STEM) competitions—is part of a series of events that culminated 23-24 October in the USA Science and Engineering Festival on the National Mall in Washington, D. C., and at 50 satellite events around the country. “We welcome championship sports teams to the White House to celebrate their victories,” Obama said, noting that the Los Angeles Lakers basketball team, New Orleans Saints football team, and others have been to the White House. “I thought we ought to do the same thing for the winners of science fair and robotic contests and math competitions, because often we don’t give these victories the attention that they deserve. When you win first place at a science fair, nobody is rushing the field or dumping Gatorade over your head [in celebration].”

  7. Neurobiology of rodent self-grooming and its value for translational neuroscience

    PubMed Central

    Kalueff, Allan V.; Stewart, Adam Michael; Song, Cai; Berridge, Kent C.; Graybiel, Ann M.; Fentress, John C.

    2016-01-01

    Self-grooming is a complex innate behaviour with an evolutionary conserved sequencing pattern and is one of the most frequently performed behavioural activities in rodents. In this Review, we discuss the neurobiology of rodent self-grooming, and we highlight studies of rodent models of neuropsychiatric disorders — including models of autism spectrum disorder and obsessive compulsive disorder — that have assessed self-grooming phenotypes. We suggest that rodent self-grooming may be a useful measure of repetitive behaviour in such models, and therefore of value to translational psychiatry. Assessment of rodent self-grooming may also be useful for understanding the neural circuits that are involved in complex sequential patterns of action. PMID:26675822

  8. Evaluation of the nutrient-upgraded rodent food bar for rodent spaceflight experiments.

    PubMed

    Sun, Gwo-Shing; Tou, Janet C; Liittschwager, Kurt; Herrera, Anna M; Hill, Esther L; Girten, Beverly; Reiss-Bubenheim, Debra; Vasques, Marilyn

    2010-01-01

    Selection of an appropriate diet for rodent spaceflight experiments is critical and may have significant effects on mission results. The National Aeronautics and Space Administration (NASA) rodent food bar (RFB) was reformulated and designated as the nutrient-upgraded RFB (NuRFB). The objectives of this study were to determine whether the NuRFB nutrient formulation meets the 1995 National Research Council (NRC) nutrient recommendations and whether the NuRFB can be used for short-term (45-d) and long-term (90-d) spaceflight experiments. Nutrient and moisture analyses of the NuRFB were performed. Young (age 13-14 wk) male Sprague-Dawley rats (n=16/group) were individually caged and fed a diet treatment consisting of 1) NuRFB, 2) RFB, or 3) modified AIN-93G containing 4% instead of the 7% fat for 45- or 90-d. At the end of the study, organs were weighted, and serum clinical chemistry indicators of organ function and hematologic measurements were determined. Chemical analysis of the diet ingredients showed that the NuRFB met the 1995 NRC nutrient recommendations for rats. Subsequent animal feeding studies showed that NuRFB was comparable to RFB and modified AIN-93G for supporting rat growth and body weight maintenance. In addition, the safety of the NuRFB for use as a spaceflight diet was indicated by the absence of changes in organ weight or function. Based on the study results, the NuRFB performed similarly to the RFB and met the criteria necessary for short-term and long-term rodent spaceflight experiments. Published by Elsevier Inc.

  9. PhenoWorld: addressing animal welfare in a new paradigm to house and assess rat behaviour.

    PubMed

    Castelhano-Carlos, Magda J; Baumans, Vera; Sousa, Nuno

    2017-02-01

    The use of animals is essential in biomedical research. The laboratory environment where the animals are housed has a major impact on them throughout their lives and influences the outcome of animal experiments. Therefore, there has been an increased effort in the refinement of laboratory housing conditions which is explicitly reflected in international regulations and recommendations. Since housing conditions affect behaviour and brain function as well as well-being, the validation of an animal model or paradigm to study the brain and central nervous system disorders is not complete without an evaluation of its implication on animal welfare. Here we discuss several aspects of animal welfare, comparing groups of six rats living in the PhenoWorld (PhW), a recently developed and validated paradigm for studying rodent behaviour, with standard-housed animals (in cages of six rats or pair-housed). In this study we present new data on home-cage behaviour showing that PhW animals have a clearer circadian pattern of sleep and social interaction. We conclude that, by promoting good basic health and functioning, together with the performance of natural behaviours, and maintaining animals' control over some of their environment but still keeping some physical and social challenges, the PhW stimulates positive affective states and higher motivation in rats, which might contribute to an increased welfare for animals living in the PhW.

  10. 75 FR 68748 - Notice of Funding Availability (NOFA): Section 515 Multi-Family Housing Preservation Revolving...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-09

    ... Independence Avenue, SW., Washington, DC 20250-0781 or by telephone at (202) 720-1094 or (202) 720-1610, TDD... Loan Division, Multi- Family Housing STOP 0781 (Room 1263-S) or by telephone at (202) 720- 1094 or (202...

  11. Risk factors for house-entry by culicine mosquitoes in a rural town and satellite villages in The Gambia

    PubMed Central

    Kirby, Matthew J; West, Philippa; Green, Clare; Jasseh, Momodou; Lindsay, Steve W

    2008-01-01

    Background Screening doors, windows and eaves of houses should reduce house entry by eusynanthropic insects, including the common African house mosquito Culex pipiens quinquefasciatus and other culicines. In the pre-intervention year of a randomized controlled trial investigating the protective effects of house screening against mosquito house entry, a multi-factorial risk factor analysis study was used to identify factors influencing house entry by culicines of nuisance biting and medical importance. These factors were house location, architecture, human occupancy and their mosquito control activities, and the number and type of domestic animals within the compound. Results 40,407 culicines were caught; the dominant species were Culex thalassius, Cx. pipiens s.l., Mansonia africanus, M. uniformis and Aedes aegypti. There were four times more Cx. pipiens s.l. in Farafenni town (geometric mean/trap/night = 8.1, 95% confidence intervals, CIs = 7.2–9.1) than in surrounding villages (2.1, 1.9–2.3), but over five times more other culicines in the villages (25.1, 22.1–28.7) than in town (4.6, 4.2–5.2). The presence of Cx. pipiens s.l. was reduced in both settings if the house had closed eaves (odds ratios, OR town = 0.62, 95% CIs = 0.49–0.77; OR village = 0.49, 0.33–0.73), but increased per additional person in the trapping room (OR town = 1.16, 1.09–1.24; OR village = 1.10, 1.02–1.18). In the town only, Cx. pipiens s.l. numbers were reduced if houses had a thatched roof (OR = 0.70, 0.51–0.96), for each additional cow tethered near the house (OR = 0.73, 0.65–0.82) and with increasing distance from a pit latrine (OR = 0.97, 0.95–0.99). In the villages a reduction in Cx. pipiens s.l. numbers correlated with increased horses in the compound (OR = 0.90, 0.82–0.99). The presence of all other culicines was reduced in houses with closed eaves (both locations), with horses tethered outside (village only) and with increasing room height (town only), but

  12. Chemical carcinogenesis: Too many rodent carcinogens

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ames, B.N.; Gold, L.S.

    1990-10-01

    The administration of chemicals at the maximum tolerated dose (MTD) in standard animal cancer tests is postulated to increase cell division (mitogenesis), which in turn increases rates of mutagenesis and thus carcinogenesis. The animal data are consistent with this mechanism, because a high proportion{endash}about half{endash}of all chemicals tested (whether natural or synthetic) are indeed rodent carcinogens. The authors conclude that at the low doses of most human exposures, where cell killing does not occur, the hazards to humans of rodent carcinogens may be much lower than is commonly assumed.

  13. Thermal comfort analysis: A case study of LIG housing in Chhattisgarh

    NASA Astrophysics Data System (ADS)

    Netam, Nisha; Sanyal, Shubhashis; Bhowmick, Shubhankar

    2016-07-01

    The present work reports the evaluation of temperature distribution inside a Low Income Group (LIG) house located in the city of Raipur, Chhattisgarh, using a Agros2D which is multi-platform C++ application capable of higher-order finite element formulation with h, p and hp adaptivity for the solution of differential equations based on the Hermes library. Variation of room air temperature along the length (x) of the house is calculated at different altitudes viz. 0.5m, 1m, 1.5m, 2m, 2.5m, and 3m. 2D model is generated for all the respective altitudes which show the temperature distribution inside the building.

  14. Tularemia and plague survey in rodents in an earthquake zone in southeastern Iran

    PubMed Central

    Gyuranecz, Miklós

    2015-01-01

    OBJECTIVES: Earthquakes are one the most common natural disasters that lead to increased mortality and morbidity from transmissible diseases, partially because the rodents displaced by an earthquake can lead to an increased rate of disease transmission. The aim of this study was to evaluate the prevalence of plague and tularemia in rodents in the earthquake zones in southeastern Iran. METHODS: In April 2013, a research team was dispatched to explore the possible presence of diseases in rodents displaced by a recent earthquake magnitude 7.7 around the cities of Khash and Saravan in Sistan and Baluchestan Province. Rodents were trapped near and in the earthquake zone, in a location where an outbreak of tularemia was reported in 2007. Rodent serums were tested for a serological survey using an enzyme-linked immunosorbent assay. RESULTS: In the 13 areas that were studied, nine rodents were caught over a total of 200 trap-days. Forty-eight fleas and 10 ticks were obtained from the rodents. The ticks were from the Hyalomma genus and the fleas were from the Xenopsylla genus. All the trapped rodents were Tatera indica. Serological results were negative for plague, but the serum agglutination test was positive for tularemia in one of the rodents. Tatera indica has never been previously documented to be involved in the transmission of tularemia. CONCLUSIONS: No evidence of the plague cycle was found in the rodents of the area, but evidence was found of tularemia infection in rodents, as demonstrated by a positive serological test for tularemia in one rodent. PMID:26602769

  15. RODENT RESISTANT CABLE MATERIALS.

    DTIC Science & Technology

    Several formulations of organotin compounds in polymeric materials were evaluated for application to polyethylene cable coatings. Tributyltin ...test the effectiveness of this formulation in protecting treated WF-16 cable from rodent damage. In a laboratory test vapors of tributyltin chloride

  16. 4. Credit USAF, ca. 1945. Original housed in the Muroc ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Credit USAF, ca. 1945. Original housed in the Muroc Flight Test Base, Unit History, 1 September 1942 - 30 June 1945. Alfred F. Simpson Historical Research Agency. United States Air Force. Maxwell AFB, Alabama. Photographic copy of photograph captioned "Hangar No. 2 Hydraulics Room." Location within Building 4402 not determined. - Edwards Air Force Base, North Base, Hangar No. 2, First & A Streets, Boron, Kern County, CA

  17. Rodent models of diabetic nephropathy: their utility and limitations

    PubMed Central

    Kitada, Munehiro; Ogura, Yoshio; Koya, Daisuke

    2016-01-01

    Diabetic nephropathy is the most common cause of end-stage renal disease. Therefore, novel therapies for the suppression of diabetic nephropathy must be developed. Rodent models are useful for elucidating the pathogenesis of diseases and testing novel therapies, and many type 1 and type 2 diabetic rodent models have been established for the study of diabetes and diabetic complications. Streptozotocin (STZ)-induced diabetic animals are widely used as a model of type 1 diabetes. Akita diabetic mice that have an Ins2+/C96Y mutation and OVE26 mice that overexpress calmodulin in pancreatic β-cells serve as a genetic model of type 1 diabetes. In addition, db/db mice, KK-Ay mice, Zucker diabetic fatty rats, Wistar fatty rats, Otsuka Long-Evans Tokushima Fatty rats and Goto-Kakizaki rats serve as rodent models of type 2 diabetes. An animal model of diabetic nephropathy should exhibit progressive albuminuria and a decrease in renal function, as well as the characteristic histological changes in the glomeruli and the tubulointerstitial lesions that are observed in cases of human diabetic nephropathy. A rodent model that strongly exhibits all these features of human diabetic nephropathy has not yet been developed. However, the currently available rodent models of diabetes can be useful in the study of diabetic nephropathy by increasing our understanding of the features of each diabetic rodent model. Furthermore, the genetic background and strain of each mouse model result in differences in susceptibility to diabetic nephropathy with albuminuria and the development of glomerular and tubulointerstitial lesions. Therefore, the validation of an animal model reproducing human diabetic nephropathy will significantly facilitate our understanding of the underlying genetic mechanisms that contribute to the development of diabetic nephropathy. In this review, we focus on rodent models of diabetes and discuss the utility and limitations of these models for the study of diabetic

  18. Plant Secondary Metabolites as Rodent Repellents: a Systematic Review.

    PubMed

    Hansen, Sabine C; Stolter, Caroline; Imholt, Christian; Jacob, Jens

    2016-09-01

    The vast number of plant secondary metabolites (PSMs) produced by higher plants has generated many efforts to exploit their potential for pest control. We performed a systematic literature search to retrieve relevant publications, and we evaluated these according to PSM groups to derive information about the potential for developing plant-derived rodent repellents. We screened a total of 54 publications where different compounds or plants were tested regarding rodent behavior/metabolism. In the search for widely applicable products, we recommend multi-species systematic screening of PSMs, especially from the essential oil and terpenoid group, as laboratory experiments have uniformly shown the strongest effects across species. Other groups of compounds might be more suitable for the management of species-specific or sex-specific issues, as the effects of some compounds on particular rodent target species or sex might not be present in non-target species or in both sexes. Although plant metabolites have potential as a tool for ecologically-based rodent management, this review demonstrates inconsistent success across laboratory, enclosure, and field studies, which ultimately has lead to a small number of currently registered PSM-based rodent repellents.

  19. Effectiveness of rodent control and monitoring techniques for a montane rainforest

    USGS Publications Warehouse

    Nelson, Jay T.; Woodworth, Bethany L.; Fancy, Steven G.; Lindsey, Gerald D.; Tweed, Eric J.

    2002-01-01

    Introduced black (Rattus rattus) and Polynesian (R. exulans) rats are damaging to native birds, insects, and plants in island ecosystems. We controlled rodent populations in a montane rainforest on the island of Hawaii to determine feasibility, cost, and effectiveness of ground-based rodent control in a rugged, remote rainforest habitat. Treatment was conducted 1996-99, from January to April each year, using rodenticide bait stations and snap-traps. We monitored rodent numbers in 48-ha treatment and reference areas before, during, and after control. As indexed by presence of rat sign in tracking tunnels or census blocks, rodent control reduced rodent abundance 58-90% each year 1 month after treatment began. There was an influx of rats into the treatment area, as shown by higher than expected numbers of rats snap-trapped on the treatment perimeter. Rodent numbers recovered to approximate pretreatment levels by the beginning of the following treatment year. Coast of equipment and supplies for rodent control for the first year was about \\$7,000 for a 1-km2 grid. After the first year, cost decreased to about \\$2,000 for 1 km2 per year. Rodent control applied continuously for 4 months each year during the breeding season may be effective in protecting nesting forest birds, but will not provide protection to plants and invertebrates vulnerable to predation throughout the year, and it is not likely to protect avian food resources.

  20. Improved protocols for the study of urinary electrolyte excretion and blood pressure in rodents: use of gel food and stepwise changes in diet composition.

    PubMed

    Nizar, Jonathan M; Bouby, Nadine; Bankir, Lise; Bhalla, Vivek

    2018-06-01

    Many experimental protocols in rodents require the comparison of groups that are fed different diets. Changes in dietary electrolyte and/or fat content can influence food intake, which can potentially introduce bias or confound the results. Unpalatable diets slow growth or cause weight loss, which is exacerbated by housing the animals in individual metabolic cages or by surgery. For balance studies in mice, small changes in body weight and food intake and low urinary flow can amplify these challenges. Powder food can be administered as gel with the addition of a desired amount of water, electrolytes, drugs (if any), and a small amount of agar. We describe here how the use of gel food to vary water, Na, K, and fat content can reduce weight loss and improve reproducibility of intake, urinary excretion, and blood pressure in rodents. In addition, mild food restriction reduces the interindividual variability and intergroup differences in food intake and associated variables, thus improving the statistical power of an experiment. Finally, we also demonstrate the advantages of using gel food for weight-based drug dosing. These protocols can improve the accuracy and reproducibility of experimental data where dietary manipulations are needed and are especially advisable in rodent studies related to water balance, obesity, and blood pressure.

  1. Semi-Autonomous Rodent Habitat for Deep Space Exploration

    NASA Technical Reports Server (NTRS)

    Alwood, J. S.; Shirazi-Fard, Y.; Pletcher, D.; Globus, R.

    2018-01-01

    NASA has flown animals to space as part of trailblazing missions and to understand the biological responses to spaceflight. Mice traveled in the Lunar Module with the Apollo 17 astronauts and now mice are frequent research subjects in LEO on the ISS. The ISS rodent missions have focused on unravelling biological mechanisms, better understanding risks to astronaut health, and testing candidate countermeasures. A critical barrier for longer-duration animal missions is the need for humans-in-the-loop to perform animal husbandry and perform routine tasks during a mission. Using autonomous or telerobotic systems to alleviate some of these tasks would enable longer-duration missions to be performed at the Deep Space Gateway. Rodent missions performed using the Gateway as a platform could address a number of critical risks identified by the Human Research Program (HRP), as well as Space Biology Program questions identified by NRC Decadal Survey on Biological and Physical Sciences in Space, (2011). HRP risk areas of potentially greatest relevance that the Gateway rodent missions can address include those related to visual impairment (VIIP) and radiation risks to central nervous system, cardiovascular disease, as well as countermeasure testing. Space Biology focus areas addressed by the Gateway rodent missions include mechanisms and combinatorial effects of microgravity and radiation. The objectives of the work proposed here are to 1) develop capability for semi-autonomous rodent research in cis-lunar orbit, 2) conduct key experiments for testing countermeasures against low gravity and space radiation. The hardware and operations system developed will enable experiments at least one month in duration, which potentially could be extended to one year in duration. To gain novel insights into the health risks to crew of deep space travel (i.e., exposure to space radiation), results obtained from Gateway flight rodents can be compared to ground control groups and separate groups

  2. Long-term population patterns of rodents and associated damage in German forestry.

    PubMed

    Imholt, Christian; Reil, Daniela; Plašil, Pavel; Rödiger, Kerstin; Jacob, Jens

    2017-02-01

    Several rodent species can damage forest trees, especially at young tree age in afforestation. Population outbreaks of field voles (Microtus agrestis L.) and bank voles (Myodes glareolus Schreber) in particular can cause losses. Analyses of long-term time series indicate good synchrony of population abundance in rodent species associated with damage in forestry. This synchrony could be related to the effect of beech (Fagus spec.) mast in the previous year on population growth rates of both species. In shorter time series from Eastern Germany, damage in forestry was mostly associated with autumn abundances of rodents. Environmental factors such as beech mast and snow cover did not explain additional variation in rodent damage to trees. Beech mast is a good indicator of long-term rodent abundance in Northern German afforestation areas. However, rodent damage to forestry in Central Germany did not seem to depend on environmental parameters other than rodent abundance at large scale. As a result, there is still uncertainty about the link between environmental predictors and rodent damage to forestry, and further experimental work is required to identify suitable environmental drivers and their interplay with other potential factors such as the local predator community. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  3. Ecosystem engineering by a colonial mammal: how prairie dogs structure rodent communities.

    PubMed

    VanNimwegen, Ron E; Kretzer, Justin; Cully, Jack F

    2008-12-01

    As ecosystem engineers, prairie dogs (Cynomys spp.) physically alter their environment, but the mechanism by which these alterations affect associated faunal composition is not well known. We examined how rodent and vegetation communities responded to prairie dog colonies and landcover at the Cimarron National Grassland in southwest Kansas, USA. We trapped rodents and measured vegetation structure on and off colonies in 2000 and 2003. We plotted two separate ordinations of trapping grids: one based on rodent counts and a second based on vegetation variables. We regressed three factors on each ordination: (1) colony (on-colony and off-colony), (2) cover (shortgrass and sandsage), and (3) habitat (factorial cross of colony x cover). Rodent communities differed by colony but not cover. Vegetation differed across both gradients. Rodent responses to habitat reflected those of colony and cover, but vegetation was found to differ across cover only in the sandsage prairie. This interaction suggested that rodent composition responded to prairie dog colonies, but independently of vegetation differences. We conclude that burrowing and soil disturbance are more important than vegetation cropping in structuring rodent communities.

  4. Thieving rodents as substitute dispersers of megafaunal seeds.

    PubMed

    Jansen, Patrick A; Hirsch, Ben T; Emsens, Willem-Jan; Zamora-Gutierrez, Veronica; Wikelski, Martin; Kays, Roland

    2012-07-31

    The Neotropics have many plant species that seem to be adapted for seed dispersal by megafauna that went extinct in the late Pleistocene. Given the crucial importance of seed dispersal for plant persistence, it remains a mystery how these plants have survived more than 10,000 y without their mutualist dispersers. Here we present support for the hypothesis that secondary seed dispersal by scatter-hoarding rodents has facilitated the persistence of these large-seeded species. We used miniature radio transmitters to track the dispersal of reputedly megafaunal seeds by Central American agoutis, which scatter-hoard seeds in shallow caches in the soil throughout the forest. We found that seeds were initially cached at mostly short distances and then quickly dug up again. However, rather than eating the recovered seeds, agoutis continued to move and recache the seeds, up to 36 times. Agoutis dispersed an estimated 35% of seeds for >100 m. An estimated 14% of the cached seeds survived to the next year, when a new fruit crop became available to the rodents. Serial video-monitoring of cached seeds revealed that the stepwise dispersal was caused by agoutis repeatedly stealing and recaching each other's buried seeds. Although previous studies suggest that rodents are poor dispersers, we demonstrate that communities of rodents can in fact provide highly effective long-distance seed dispersal. Our findings suggest that thieving scatter-hoarding rodents could substitute for extinct megafaunal seed dispersers of tropical large-seeded trees.

  5. Endoparasites of Wild Rodents in Southeastern Iran

    PubMed Central

    Nateghpour, Mehdi; Motevalli-Haghi, Afsaneh; Akbarzadeh, Kamran; Akhavan, Amir Ahmad; Mohebali, Mehdi; Mobedi, Iraj; Farivar, Leila

    2015-01-01

    Background: This study was aimed to collect wild rodents for endoparasites determination in some parts of Sistan and Baluchistan Province, southeastern Iran nearby Pakistan and Afghanistan countries. Methods: A total of 100 wild rodents were captured alive with cage traps. Various samples were collected from blood and feces, also impression smear prepared from different organs. The samples were prepared by formalin-ether or stained with Giemsa, after that were examined under microscope. Results: All the caught rodents (47 Tatera indica, 44 Meriones hurriana, 5 Gerbilus nanus and 4 Meriones libycus) were studied for endoparasites emphasizing to their zoonotic aspects. Endoparasites including Spirurida, Hymenolepis diminuta, Hymenolepis nana feraterna, Trichuris trichiura, Skerjabino taenia, Trichostrongylus spp, Entamoeba muris, Chilomastix mesnili and Leishmania spp were parasitologically identified. Conclusion: Among 9 genera or species of the identified parasites at least 5 of them have zoonotic and public health importance. PMID:26114139

  6. The form concept of Kudus traditional house in Langgar Dalem village

    NASA Astrophysics Data System (ADS)

    Setyowati, Wiwit; Nugradi, Didik N. A.; Dermawan, Husni

    2018-03-01

    Javanese Traditional houses have many variations, one of them is Kudus traditional house. Today, condition of Kudus traditional houses is very apprehensive. Hundreds of traditional houses have been lost because they are sold to various cities and countries. It takes conservation effort of Kudus Traditional House (pencu house) with conservation based on local wisdom. The purpose of this study to understand the form concept of Kudus traditional house. Location is on Langgar Dalem village, Kota sub-distric, Kudus Regency, where there are several Kudus traditional houses which are still awake in their local wisdom. This research using analytical descriptive method. In the research known that the form of Kudus traditional house in Langgar Dalem Village is "Joglo-Pencu" who look mighty and elegant. This symbolizes the inhabitants physical form (handsome and mighty). The inhabitants of the house is symbolized as Sang Sukma, who merges, filling, taking care, maintaining and guard own home with the best. Joglo Pencu house looks towering toward the sky, symbolizing the high power of God over man. The roof of Kudus traditional house in Langgar Dalem village is made from tile. Above the tile there are gendeng, which in general pattern of gendeng head is plant (salur-saluran) as a feature of Islamic culture. Gendeng types located in Langgar Dalem Kudus Village is Gendeng Wedok (gelak cekak), Gendeng Gajah (escort gendeng in rooftop), and Gendeng Raja (middle gendeng on rooftop). Saka Guru and Umpak in Kudus traditional house is no ornament. The Kudus traditional house stands on a base consisting of 5 (five) traps above the surface of the ground, namely Bancik kapisan (bottom trap), Bachik kapindho (second trap from below), Bancik ketelu (third trap from below), Jogan Jogosatru (Trap floor of the front room), Jogan Lebet (indoor floor trap). Five ground floor of the house leads inhabitants obedient to carry out 5 (five) pillars of Islam, for the happiness in the world and the

  7. Rodent Models of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis

    PubMed Central

    Imajo, Kento; Yoneda, Masato; Kessoku, Takaomi; Ogawa, Yuji; Maeda, Shin; Sumida, Yoshio; Hyogo, Hideyuki; Eguchi, Yuichiro; Wada, Koichiro; Nakajima, Atsushi

    2013-01-01

    Research in nonalcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH), has been limited by the availability of suitable models for this disease. A number of rodent models have been described in which the relevant liver pathology develops in an appropriate metabolic context. These models are promising tools for researchers investigating one of the key issues of NASH: not so much why steatosis occurs, but what causes the transition from simple steatosis to the inflammatory, progressive fibrosing condition of steatohepatitis. The different rodent models can be classified into two large groups. The first includes models in which the disease is acquired after dietary or pharmacological manipulation, and the second, genetically modified models in which liver disease develops spontaneously. To date, no single rodent model has encompassed the full spectrum of human disease progression, but individual models can imitate particular characteristics of human disease. Therefore, it is important that researchers choose the appropriate rodent models. The purpose of the present review is to discuss the metabolic abnormalities present in the currently available rodent models of NAFLD, summarizing the strengths and weaknesses of the established models and the key findings that have furthered our understanding of the disease’s pathogenesis. PMID:24192824

  8. Does age matter? The impact of rodent age on study outcomes.

    PubMed

    Jackson, Samuel J; Andrews, Nick; Ball, Doug; Bellantuono, Ilaria; Gray, James; Hachoumi, Lamia; Holmes, Alan; Latcham, Judy; Petrie, Anja; Potter, Paul; Rice, Andrew; Ritchie, Alison; Stewart, Michelle; Strepka, Carol; Yeoman, Mark; Chapman, Kathryn

    2017-04-01

    Rodent models produce data which underpin biomedical research and non-clinical drug trials, but translation from rodents into successful clinical outcomes is often lacking. There is a growing body of evidence showing that improving experimental design is key to improving the predictive nature of rodent studies and reducing the number of animals used in research. Age, one important factor in experimental design, is often poorly reported and can be overlooked. The authors conducted a survey to assess the age used for a range of models, and the reasoning for age choice. From 297 respondents providing 611 responses, researchers reported using rodents most often in the 6-20 week age range regardless of the biology being studied. The age referred to as 'adult' by respondents varied between six and 20 weeks. Practical reasons for the choice of rodent age were frequently given, with increased cost associated with using older animals and maintenance of historical data comparability being two important limiting factors. These results highlight that choice of age is inconsistent across the research community and often not based on the development or cellular ageing of the system being studied. This could potentially result in decreased scientific validity and increased experimental variability. In some cases the use of older animals may be beneficial. Increased scientific rigour in the choice of the age of rodent may increase the translation of rodent models to humans.

  9. First detection of Echinococcus multilocularis in rodent intermediate hosts in Turkey.

    PubMed

    Avcioglu, Hamza; Guven, Esin; Balkaya, Ibrahim; Kirman, Ridvan; Bia, Mohammed Mebarek; Gulbeyen, Hatice; Kurt, Ali; Yaya, Sali; Demirtas, Sadik

    2017-11-01

    Echinococcus multilocularis is the causative agent of alveolar echinococcosis (AE), a potentially fatal zoonotic disease. Large parts of Turkey are considered as endemic for E. multilocularis. The aim of this study was to determine the occurrence of metacestode of E. multilocularis in wild rodents in Erzurum, an endemic region for human AE in Turkey. During the sampling period, a total of 498 rodents were trapped in twenty counties of Erzurum Province. Suspected lesions were observed on the livers of 48 rodents, and then partial fragment of mitochondrial 12S rRNA gene was PCR-amplified. Five liver samples exhibited E. multilocularis infection. The prevalence of E. multilocularis for Microtus spp. was 1·3%. All of the infected rodents had fertile metacestodes. Infected rodents were morphologically and molecularly analysed and were confirmed to be Microtus irani by the mitochondrial cytochrome b gene sequence analysis. This is the first report of the presence of E. multilocularis in rodent intermediate hosts in Turkey. Our findings of infected M. irani with protoscoleces show that this rodent can act as suitable intermediate host for E. multilocularis' life cycle in Turkey. However, there was a complete lack of data on the infection of carnivores from the country. An extensive survey is recommended to determine the prevalence of E. multilocularis in definitive hosts in this endemic region.

  10. Low-Pathogenic Avian Influenza Viruses in Wild House Mice

    PubMed Central

    Shriner, Susan A.; VanDalen, Kaci K.; Mooers, Nicole L.; Ellis, Jeremy W.; Sullivan, Heather J.; Root, J. Jeffrey; Pelzel, Angela M.; Franklin, Alan B.

    2012-01-01

    Background Avian influenza viruses are known to productively infect a number of mammal species, several of which are commonly found on or near poultry and gamebird farms. While control of rodent species is often used to limit avian influenza virus transmission within and among outbreak sites, few studies have investigated the potential role of these species in outbreak dynamics. Methodology/Principal Findings We trapped and sampled synanthropic mammals on a gamebird farm in Idaho, USA that had recently experienced a low pathogenic avian influenza outbreak. Six of six house mice (Mus musculus) caught on the outbreak farm were presumptively positive for antibodies to type A influenza. Consequently, we experimentally infected groups of naïve wild-caught house mice with five different low pathogenic avian influenza viruses that included three viruses derived from wild birds and two viruses derived from chickens. Virus replication was efficient in house mice inoculated with viruses derived from wild birds and more moderate for chicken-derived viruses. Mean titers (EID50 equivalents/mL) across all lung samples from seven days of sampling (three mice/day) ranged from 103.89 (H3N6) to 105.06 (H4N6) for the wild bird viruses and 102.08 (H6N2) to 102.85 (H4N8) for the chicken-derived viruses. Interestingly, multiple regression models indicated differential replication between sexes, with significantly (p<0.05) higher concentrations of avian influenza RNA found in females compared with males. Conclusions/Significance Avian influenza viruses replicated efficiently in wild-caught house mice without adaptation, indicating mice may be a risk pathway for movement of avian influenza viruses on poultry and gamebird farms. Differential virus replication between males and females warrants further investigation to determine the generality of this result in avian influenza disease dynamics. PMID:22720076

  11. Plum Brook Reactor Facility Control Room during Facility Startup

    NASA Image and Video Library

    1961-02-21

    Operators test the National Aeronautics and Space Administration’s (NASA) Plum Brook Reactor Facility systems in the months leading up to its actual operation. The “Reactor On” signs are illuminated but the reactor core was not yet ready for chain reactions. Just a couple weeks after this photograph, Plum Brook Station held a media open house to unveil the 60-megawatt test reactor near Sandusky, Ohio. More than 60 members of the print media and radio and television news services met at the site to talk with community leaders and representatives from NASA and Atomic Energy Commission. The Plum Brook reactor went critical for the first time on the evening of June 14, 1961. It was not until April 1963 that the reactor reached its full potential of 60 megawatts. The reactor control room, located on the second floor of the facility, was run by licensed operators. The operators manually operated the shim rods which adjusted the chain reaction in the reactor core. The regulating rods could partially or completely shut down the reactor. The control room also housed remote area monitoring panels and other monitoring equipment that allowed operators to monitor radiation sensors located throughout the facility and to scram the reactor instantly if necessary. The color of the indicator lights corresponded with the elevation of the detectors in the various buildings. The reactor could also shut itself down automatically if the monitors detected any sudden irregularities.

  12. 4. EXTERIOR VIEW OF HILLMAN FAN HOUSE LOOKING NORTHEAST This ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. EXTERIOR VIEW OF HILLMAN FAN HOUSE LOOKING NORTHEAST This view shows the concrete roof covering the airways and the engine room. The reinforced concrete roof is supported by metal beams. Note how the airshaft, in the foreground, widens to create an airway on either side for the double inlet fan. The brick fan housing is capped by a curved sheet metal roof whose segments are bolted together. The brick updraft chimney, capped with concrete, is to the rear (northeast). Also evident on the wall is the cover over the air velocity indicator. The Hollenback Cemetery, which adjoins the Dorrance Colliery property is in the background. - Dorrance Colliery Fan Complex, South side of Susquehanna River at Route 115 & Riechard Street, Wilkes-Barre, Luzerne County, PA

  13. Rodent-borne infectious disease outbreaks after flooding disasters: Epidemiology, management, and prevention.

    PubMed

    Diaz, James H

    2015-01-01

    To alert clinicians to the climatic conditions that can precipitate outbreaks of the rodent-borne infectious diseases most often associated with flooding disasters, leptospirosis (LS), and the Hantavirus-caused diseases, hemorrhagic fever with renal syndrome (HFRS) and Hantavirus pulmonary syndrome (HPS); to describe the epidemiology and presenting clinical manifestations and outcomes of these rodent-borne infectious diseases; and to recommend both prophylactic therapies and effective control and prevention strategies for rodent-borne infectious diseases. Internet search engines, including Google®, Google Scholar®, Pub Med, Medline, and Ovid, were queried with the key words as search terms to examine the latest scientific articles on rodent-borne infectious disease outbreaks in the United States and worldwide to describe the epidemiology and presenting clinical manifestations and outcomes of LS and Hantavirus outbreaks. Not applicable. Not applicable. Not applicable. Rodent-borne infectious disease outbreaks following heavy rainfall and flooding disasters. Heavy rainfall encourages excessive wild grass seed production that supports increased outdoor rodent population densities; and flooding forces rodents from their burrows near water sources into the built environment and closer to humans. Healthcare providers should maintain high levels of suspicion for LS in patients developing febrile illnesses after contaminated freshwater exposures following heavy rainfall, flooding, and even freshwater recreational events; and for Hantavirus-caused infectious diseases in patients with hemorrhagic fevers that progress rapidly to respiratory or renal failure following rodent exposures.

  14. Natural Intestinal Protozoa in Rodents (Rodentia: Gerbillinae, Murinae, Cricetinae) in Northwestern Iran.

    PubMed

    Mohebali, Mehdi; Zarei, Zabiholah; Khanaliha, Khadijeh; Kia, Eshrat Beigom; Motavalli-Haghi, Afsaneh; Davoodi, Jaber; Rezaeian, Tahereh; Tarighi, Fathemeh; Rezaeian, Mostafa

    2017-01-01

    Majority of parasitic infections in rodents have zoonotic importance. This study aimed to determine the frequency and intensity of intestinal protozoa infections of rodents including Meriones persicus, Mus musculus and, C ricetulus migratorius . This survey was conducted in Meshkin Shahr district in northwestern Iran from Mar. to Dec. of 2014. Intestinal samples of 204 rodents including M. persicus (n=117), M. musculus (n=63) and C. migratorius (n=24) were parasitologically examined. Formalin-ether concentration method was done for all of rodents stool samples and observed with light microscope. All of suspected cases were stained with trichorome staining Method. Cultivation in dichromate potassium 2.5% was carried out for all of coccidian positive samples. Acid fast and aniline blue staining methods were used for detecting of coccidian oocysts and intestinal microsporidial spores, respectively. About 121(59.3%) of the caught rodents were generally infected with intestinal protozoa. Entamoeba muris 14(6.9%), Trichomonas muris 55(27.0%), Chilomastix betencourtti 17 (8.3%), Giardia muris 19(9.3%), Eimeria spp. 46(22.5%) , Isospora spp. 4(2%) and Cryptosporidium spp. 1(0.5%) were found from the collected rodents. Microsporidian spores were identified in 63 (31%) out of the 204 collected rodents using aniline blue staining method. Since some of the infections are zoonotic importance thus, control of rodents can be decreased new cases of the parasitic zoonoses in humans.

  15. Potential of Eucalyptus Oil as Repellent against House Rat, Rattus rattus

    PubMed Central

    Thind, Ramandeep Kaur; Mahal, Amrit Kaur

    2014-01-01

    Rodent repellents are chemicals which by taste or odour or possibly by both will prevent animal from feeding or gnawing. Such substances may be used in protecting an area from rodent infestation or in protecting packaged food, packing materials, electric cables, and other important vulnerable materials. Mature and healthy house rat, Rattus rattus of both sexes, was exposed to 5, 10, and 20% eucalyptus oil applied as spray in laboratory pens in bichoice tests. Each concentration was applied through three different modes of application, that is, daily, once, and alternatively in a week. Repellent effect of the oil was assessed based on food consumption from treated and untreated sides for four days. In overall, food consumption was significantly (P < 0.0001) low from treatment side compared to the untreated side indicating significant repellent effect of the oil at all the three concentrations tested. Repellent effect of the oil was, however, not found to differ significantly between the two sexes. Percent repellency in both male and female rats was apparently more with daily application of 5 and 10% eucalyptus oil. Present studies reveal the potential of eucalyptus oil in repelling away R. rattus; however, further studies may be conducted to enhance the persistence of repellent effect for longer period of time. PMID:24523633

  16. House Dust Mite Prevalence in the House of Patients with Atopic Dermatitis in Mashhad, Iran.

    PubMed

    Ziyaei, Toktam; Berenji, Fariba; Jabbari-Azad, Farahzad; Fata, Abdolmajid; Jarahi, Lida; Fereidouni, Mohammad

    2017-06-01

    Being exposed to house dust mites intensifies atopic dermatitis. This study has investigated the contamination rate with Dermatophagoides mites in patient's residential home with atopic dermatitis. In this cross-sectional study, 40 patients took part with atopic dermatitis (positive or negative for mites by prick Dermal Test). Samples were collected from 3 locations (living room, bedroom and bed) by vacuum cleaner. Dust samples (transferred to freezer -20 °C) were examined by direct method and flotation. The data were analyzed using statistical SPSS vr.20 software. Twenty patients of positive prick test included 8 (40%) male and 12 (60%) female. The results of direct observation of mites: 7 cases (35%) in bedding sheets, 6 cases (30%) bedrooms' carpet, 3 cases (15%) living room's carpet. Twenty patients of negative prick test included 8 (40%) male and 12 (60%) female. Only mites were found (5%) in living room's carpets of negative prick test patients. Dermatophagoides pteronyssinus was more frequent than Dermatophagoides farina e. (98% vs 83%). Fifty-five percent of residential homes of prick test positive patients and only 5% of residential homes of prick test negative patients were positive for mite. Sunshine provided home had fewer mites than home where sunshine is not provided. Prick test positive patients used handmade carpets more than machine made ones. In positive prick test patients, mites were found in bed sheet and bedroom's carpet more than negative prick test patient's sheets and carpets.

  17. Multiple infections of rodents with zoonotic pathogens in Austria.

    PubMed

    Schmidt, Sabrina; Essbauer, Sandra S; Mayer-Scholl, Anne; Poppert, Sven; Schmidt-Chanasit, Jonas; Klempa, Boris; Henning, Klaus; Schares, Gereon; Groschup, Martin H; Spitzenberger, Friederike; Richter, Dania; Heckel, Gerald; Ulrich, Rainer G

    2014-07-01

    Rodents are important reservoirs for a large number of zoonotic pathogens. We examined the occurrence of 11 viral, bacterial, and parasitic agents in rodent populations in Austria, including three different hantaviruses, lymphocytic choriomeningitis virus, orthopox virus, Leptospira spp., Borrelia spp., Rickettsia spp., Bartonella spp., Coxiella burnetii, and Toxoplasma gondii. In 2008, 110 rodents of four species (40 Clethrionomys glareolus, 29 Apodemus flavicollis, 26 Apodemus sylvaticus, and 15 Microtus arvalis) were trapped at two rural sites in Lower Austria. Chest cavity fluid and samples of lung, spleen, kidney, liver, brain, and ear pinna skin were collected. We screened selected tissue samples for hantaviruses, lymphocytic choriomeningitis virus, orthopox viruses, Leptospira, Borrelia, Rickettsia, Bartonella spp., C. burnetii, and T. gondii by RT-PCR/PCR and detected nucleic acids of Tula hantavirus, Leptospira spp., Borrelia afzelii, Rickettsia spp., and different Bartonella species. Serological investigations were performed for hantaviruses, lymphocytic choriomeningitis virus, orthopox viruses, and Rickettsia spp. Here, Dobrava-Belgrade hantavirus-, Tula hantavirus-, lymphocytic choriomeningitis virus-, orthopox virus-, and rickettsia-specific antibodies were demonstrated. Puumala hantavirus, C. burnetii, and T. gondii were neither detected by RT-PCR/PCR nor by serological methods. In addition, multiple infections with up to three pathogens were shown in nine animals of three rodent species from different trapping sites. In conclusion, these results show that rodents in Austria may host multiple zoonotic pathogens. Our observation raises important questions regarding the interactions of different pathogens in the host, the countermeasures of the host's immune system, the impact of the host-pathogen interaction on the fitness of the host, and the spread of infectious agents among wild rodents and from those to other animals or humans.

  18. Multiple Infections of Rodents with Zoonotic Pathogens in Austria

    PubMed Central

    Schmidt, Sabrina; Essbauer, Sandra S.; Mayer-Scholl, Anne; Poppert, Sven; Schmidt-Chanasit, Jonas; Klempa, Boris; Henning, Klaus; Schares, Gereon; Groschup, Martin H.; Spitzenberger, Friederike; Richter, Dania; Heckel, Gerald

    2014-01-01

    Abstract Rodents are important reservoirs for a large number of zoonotic pathogens. We examined the occurrence of 11 viral, bacterial, and parasitic agents in rodent populations in Austria, including three different hantaviruses, lymphocytic choriomeningitis virus, orthopox virus, Leptospira spp., Borrelia spp., Rickettsia spp., Bartonella spp., Coxiella burnetii, and Toxoplasma gondii. In 2008, 110 rodents of four species (40 Clethrionomys glareolus, 29 Apodemus flavicollis, 26 Apodemus sylvaticus, and 15 Microtus arvalis) were trapped at two rural sites in Lower Austria. Chest cavity fluid and samples of lung, spleen, kidney, liver, brain, and ear pinna skin were collected. We screened selected tissue samples for hantaviruses, lymphocytic choriomeningitis virus, orthopox viruses, Leptospira, Borrelia, Rickettsia, Bartonella spp., C. burnetii, and T. gondii by RT-PCR/PCR and detected nucleic acids of Tula hantavirus, Leptospira spp., Borrelia afzelii, Rickettsia spp., and different Bartonella species. Serological investigations were performed for hantaviruses, lymphocytic choriomeningitis virus, orthopox viruses, and Rickettsia spp. Here, Dobrava-Belgrade hantavirus-, Tula hantavirus-, lymphocytic choriomeningitis virus-, orthopox virus-, and rickettsia-specific antibodies were demonstrated. Puumala hantavirus, C. burnetii, and T. gondii were neither detected by RT-PCR/PCR nor by serological methods. In addition, multiple infections with up to three pathogens were shown in nine animals of three rodent species from different trapping sites. In conclusion, these results show that rodents in Austria may host multiple zoonotic pathogens. Our observation raises important questions regarding the interactions of different pathogens in the host, the countermeasures of the host's immune system, the impact of the host–pathogen interaction on the fitness of the host, and the spread of infectious agents among wild rodents and from those to other animals or humans. PMID

  19. PREDICTIVE SIMULATION MODELING FOR ANTIANDROGEN IMPACTS ON RODENT PROSTATE

    EPA Science Inventory

    Predictive simulation modeling for antiandrogen impacts on rodent prostate
    HA Barton1, RW Setzer1, LK Potter1,2
    1US EPA, ORD, NHEERL, ETD, PKB, Research Triangle Park, NC and 2Curriculum in Toxicology, UNC, Chapel Hill, NC

    Changes in rodent prostate weight and functi...

  20. 77 FR 38073 - Laboratory Animal Welfare: Clarification of Position Statements on Implementation of the Eighth...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-26

    ...) Nonhuman Primate Housing, (2c) Rodent Housing, and (3) Non-Pharmaceutical-Grade Substances. FOR FURTHER... January 2011 by the National Research Council of the National Academy of Sciences. (See http://www.nap.edu...) Nonhuman Primate Housing, (2c) Rodent Housing, and (3) Non-Pharmaceutical-Grade Substances. (See http...

  1. Sleep in the Cape Mole Rat: A Short-Sleeping Subterranean Rodent.

    PubMed

    Kruger, Jean-Leigh; Gravett, Nadine; Bhagwandin, Adhil; Bennett, Nigel C; Archer, Elizabeth K; Manger, Paul R

    2016-01-01

    The Cape mole rat Georychus capensis is a solitary subterranean rodent found in the western and southern Cape of South Africa. This approximately 200-gram bathyergid rodent shows a nocturnal circadian rhythm, but sleep in this species is yet to be investigated. Using telemetric recordings of the electroencephalogram (EEG) and electromyogram (EMG) in conjunction with video recordings, we were able to show that the Cape mole rat, like all other rodents, has sleep periods composed of both rapid eye movement (REM) and slow-wave (non-REM) sleep. These mole rats spent on average 15.4 h awake, 7.1 h in non-REM sleep and 1.5 h in REM sleep each day. Cape mole rats sleep substantially less than other similarly sized terrestrial rodents but have a similar percentage of total sleep time occupied by REM sleep. In addition, the duration of both non-REM and REM sleep episodes was markedly shorter in the Cape mole rat than has been observed in terrestrial rodents. Interestingly, these features (total sleep time and episode duration) are similar to those observed in another subterranean bathyergid mole rat, i.e. Fukomys mechowii. Thus, there appears to be a bathyergid type of sleep amongst the rodents that may be related to their environment and the effect of this on their circadian rhythm. Investigating further species of bathyergid mole rats may fully define the emerging picture of sleep in these subterranean African rodents. © 2016 S. Karger AG, Basel.

  2. Does age matter? The impact of rodent age on study outcomes

    PubMed Central

    Andrews, Nick; Ball, Doug; Bellantuono, Ilaria; Gray, James; Hachoumi, Lamia; Holmes, Alan; Latcham, Judy; Petrie, Anja; Potter, Paul; Rice, Andrew; Ritchie, Alison; Stewart, Michelle; Strepka, Carol; Yeoman, Mark; Chapman, Kathryn

    2016-01-01

    Rodent models produce data which underpin biomedical research and non-clinical drug trials, but translation from rodents into successful clinical outcomes is often lacking. There is a growing body of evidence showing that improving experimental design is key to improving the predictive nature of rodent studies and reducing the number of animals used in research. Age, one important factor in experimental design, is often poorly reported and can be overlooked. The authors conducted a survey to assess the age used for a range of models, and the reasoning for age choice. From 297 respondents providing 611 responses, researchers reported using rodents most often in the 6–20 week age range regardless of the biology being studied. The age referred to as ‘adult’ by respondents varied between six and 20 weeks. Practical reasons for the choice of rodent age were frequently given, with increased cost associated with using older animals and maintenance of historical data comparability being two important limiting factors. These results highlight that choice of age is inconsistent across the research community and often not based on the development or cellular ageing of the system being studied. This could potentially result in decreased scientific validity and increased experimental variability. In some cases the use of older animals may be beneficial. Increased scientific rigour in the choice of the age of rodent may increase the translation of rodent models to humans. PMID:27307423

  3. Fungal extracellular polysaccharides in house dust as a marker for exposure to fungi: relations with culturable fungi, reported home dampness, and respiratory symptoms.

    PubMed

    Douwes, J; van der Sluis, B; Doekes, G; van Leusden, F; Wijnands, L; van Strien, R; Verhoeff, A; Brunekreef, B

    1999-03-01

    Epidemiologic studies have demonstrated an association between indoor fungal growth and respiratory symptoms. However, in only a few studies was fungal exposure actually measured. The purpose of this study was to evaluate the measurement by enzyme immunoassay of extracellular polysaccharides of Aspergillus and Penicillium species (EPS-Asp/Pen ) in house dust as a marker for fungal exposure and to study the relations between EPS-Asp/Pen levels and home dampness and respiratory symptoms in children. Extracts of house dust samples from bedroom and living room floors and mattresses from homes of 31 children with chronic respiratory symptoms and 29 children with no chronic respiratory symptoms were analyzed for EPS-Asp/Pen. EPS-Asp/Pen were readily detectable (40 to 46,513 nanogram equivalent/g dust) in 161 house dust extracts, with highest concentrations in living room floor dust. EPS-Asp/Pen levels were 2 to 3 times higher on carpeted floors than on smooth floors. EPS-Asp/Pen were significantly correlated with total culturable fungi (r = 0.3 to 0.5) and with house dust mite allergens (r = 0.3 to 0.5). EPS-Asp/Pen levels in living room floor dust were positively associated with occupant-reported home dampness. This was not observed for EPS-Asp/Pen in bedroom floor and mattress dust. EPS-Asp/Pen levels in living room floor dust were positively associated with respiratory symptoms. EPS-Asp/Pen in bedroom floor and mattress dust showed a reversed association with respiratory symptoms, possibly because of allergen-avoidance measures taken in the bedroom. The enzyme immunoassay for fungal EPS-Asp/Pen may be a useful method for exposure assessment of indoor fungi.

  4. Rodents as a Source of Salmonella Contamination in Wet Markets in Thailand.

    PubMed

    Ribas, Alexis; Saijuntha, Weerachai; Agatsuma, Takeshi; Prantlová, Veronika; Poonlaphdecha, Srisupaph

    2016-08-01

    Few studies have been conducted on the presence of Salmonella in the rodents that inhabit the wet markets that play an important role in daily life in Southeast Asia. The results of studies of rodents as carriers of Salmonella vary greatly, ranging from an absence of Salmonella to high prevalences. Previous studies investigated habitats such as farms and urban and wild areas where there is less rodent-human interaction than in wet markets. Consequently, the potential role of rodents as reservoirs and transmitters of Salmonella in wet markets is of great interest. Rodents were trapped in eight traditional wet markets in Thailand and identified to species level. Subsequently, they were screened for Salmonella and isolates were serotyped. A total of 110 rats (Rattus norvegicus and Rattus exulans) were examined. Overall, the prevalence of Salmonella in rats was 49.10%, but varied between 0% and 73.3% among markets. Three serovars were identified: Salmonella Typhimurium (30%), S. Weltevreden (12.7%), and S. 4,[5],12:i:- (6.4%). Our results show that rodents in wet markets are a potential reservoir of Salmonella due to the close contact they have with humans and food. The three isolated serovars, of which serovar S. 4,[5],12:i:- is reported for the first time in rodents, are among the 10 commonest serovars isolated from humans in Thailand. Thus, more attention should be paid to rodents as potential reservoirs of Salmonella.

  5. Natural Intestinal Protozoa in Rodents (Rodentia: Gerbillinae, Murinae, Cricetinae) in Northwestern Iran

    PubMed Central

    MOHEBALI, Mehdi; ZAREI, Zabiholah; Khanaliha, Khadijeh; KIA, Eshrat Beigom; MOTAVALLI-HAGHI, Afsaneh; DAVOODI, Jaber; REZAEIAN, Tahereh; TARIGHI, Fathemeh; REZAEIAN, Mostafa

    2017-01-01

    Background: Majority of parasitic infections in rodents have zoonotic importance. This study aimed to determine the frequency and intensity of intestinal protozoa infections of rodents including Meriones persicus, Mus musculus and, Cricetulus migratorius. Methods: This survey was conducted in Meshkin Shahr district in northwestern Iran from Mar. to Dec. of 2014. Intestinal samples of 204 rodents including M. persicus (n=117), M. musculus (n=63) and C. migratorius (n=24) were parasitologically examined. Formalin-ether concentration method was done for all of rodents stool samples and observed with light microscope. All of suspected cases were stained with trichorome staining Method. Cultivation in dichromate potassium 2.5% was carried out for all of coccidian positive samples. Acid fast and aniline blue staining methods were used for detecting of coccidian oocysts and intestinal microsporidial spores, respectively. Results: About 121(59.3%) of the caught rodents were generally infected with intestinal protozoa. Entamoeba muris 14(6.9%), Trichomonas muris 55(27.0%), Chilomastix betencourtti 17 (8.3%), Giardia muris 19(9.3%), Eimeria spp. 46(22.5%), Isospora spp. 4(2%) and Cryptosporidium spp. 1(0.5%) were found from the collected rodents. Microsporidian spores were identified in 63 (31%) out of the 204 collected rodents using aniline blue staining method. Conclusion: Since some of the infections are zoonotic importance thus, control of rodents can be decreased new cases of the parasitic zoonoses in humans. PMID:28979348

  6. Automated recording of home cage activity and temperature of individual rats housed in social groups: The Rodent Big Brother project

    PubMed Central

    Tse, Karen; Grant, Claire; Keerie, Amy; Simpson, David J.; Pedersen, John C.; Rimmer, Victoria; Leslie, Lauren; Klein, Stephanie K.; Karp, Natasha A.; Sillito, Rowland; Chartsias, Agis; Lukins, Tim; Heward, James; Vickers, Catherine; Chapman, Kathryn; Armstrong, J. Douglas

    2017-01-01

    Measuring the activity and temperature of rats is commonly required in biomedical research. Conventional approaches necessitate single housing, which affects their behavior and wellbeing. We have used a subcutaneous radiofrequency identification (RFID) transponder to measure ambulatory activity and temperature of individual rats when group-housed in conventional, rack-mounted home cages. The transponder location and temperature is detected by a matrix of antennae in a baseplate under the cage. An infrared high-definition camera acquires side-view video of the cage and also enables automated detection of vertical activity. Validation studies showed that baseplate-derived ambulatory activity correlated well with manual tracking and with side-view whole-cage video pixel movement. This technology enables individual behavioral and temperature data to be acquired continuously from group-housed rats in their familiar, home cage environment. We demonstrate its ability to reliably detect naturally occurring behavioral effects, extending beyond the capabilities of routine observational tests and conventional monitoring equipment. It has numerous potential applications including safety pharmacology, toxicology, circadian biology, disease models and drug discovery. PMID:28877172

  7. Automated recording of home cage activity and temperature of individual rats housed in social groups: The Rodent Big Brother project.

    PubMed

    Redfern, William S; Tse, Karen; Grant, Claire; Keerie, Amy; Simpson, David J; Pedersen, John C; Rimmer, Victoria; Leslie, Lauren; Klein, Stephanie K; Karp, Natasha A; Sillito, Rowland; Chartsias, Agis; Lukins, Tim; Heward, James; Vickers, Catherine; Chapman, Kathryn; Armstrong, J Douglas

    2017-01-01

    Measuring the activity and temperature of rats is commonly required in biomedical research. Conventional approaches necessitate single housing, which affects their behavior and wellbeing. We have used a subcutaneous radiofrequency identification (RFID) transponder to measure ambulatory activity and temperature of individual rats when group-housed in conventional, rack-mounted home cages. The transponder location and temperature is detected by a matrix of antennae in a baseplate under the cage. An infrared high-definition camera acquires side-view video of the cage and also enables automated detection of vertical activity. Validation studies showed that baseplate-derived ambulatory activity correlated well with manual tracking and with side-view whole-cage video pixel movement. This technology enables individual behavioral and temperature data to be acquired continuously from group-housed rats in their familiar, home cage environment. We demonstrate its ability to reliably detect naturally occurring behavioral effects, extending beyond the capabilities of routine observational tests and conventional monitoring equipment. It has numerous potential applications including safety pharmacology, toxicology, circadian biology, disease models and drug discovery.

  8. Geographic Distribution of Hantaviruses Associated with Neotomine and Sigmodontine Rodents, Mexico

    PubMed Central

    Milazzo, Mary L.; Cajimat, Maria N.B.; Romo, Hannah E.; Estrada-Franco, Jose G.; Iñiguez-Dávalos, L. Ignacio; Bradley, Robert D.

    2012-01-01

    To increase our knowledge of the geographic distribution of hantaviruses associated with neotomine or sigmodontine rodents in Mexico, we tested 876 cricetid rodents captured in 18 Mexican states (representing at least 44 species in the subfamily Neotominae and 10 species in the subfamily Sigmodontinae) for anti-hantavirus IgG. We found antibodies against hantavirus in 35 (4.0%) rodents. Nucleotide sequence data from 5 antibody-positive rodents indicated that Sin Nombre virus (the major cause of hantavirus pulmonary syndrome [HPS] in the United States) is enzootic in the Mexican states of Nuevo León, San Luis Potosí, Tamaulipas, and Veracruz. However, HPS has not been reported from these states, which suggests that in northeastern Mexico, HPS has been confused with other rapidly progressive, life-threatening respiratory diseases. Analyses of nucleotide sequence data from 19 other antibody-positive rodents indicated that El Moro Canyon virus and Limestone Canyon virus are geographically widely distributed in Mexico. PMID:22469569

  9. Distinct Leishmania Species Infecting Wild Caviomorph Rodents (Rodentia: Hystricognathi) from Brazil

    PubMed Central

    Cássia-Pires, Renata; Boité, Mariana C.; D'Andrea, Paulo S.; Herrera, Heitor M.; Cupolillo, Elisa; Jansen, Ana Maria; Roque, André Luiz R.

    2014-01-01

    Background Caviomorph rodents, some of the oldest Leishmania spp. hosts, are widely dispersed in Brazil. Despite both experimental and field studies having suggested that these rodents are potential reservoirs of Leishmania parasites, not more than 88 specimens were analyzed in the few studies of natural infection. Our hypothesis was that caviomorph rodents are inserted in the transmission cycles of Leishmania in different regions, more so than is currently recognized. Methodology We investigated the Leishmania infection in spleen fragments of 373 caviomorph rodents from 20 different species collected in five Brazilian biomes in a period of 13 years. PCR reactions targeting kDNA of Leishmania sp. were used to diagnose infection, while Leishmania species identification was performed by DNA sequencing of the amplified products obtained in the HSP70 (234) targeting. Serology by IFAT was performed on the available serum of these rodents. Principal findings In 13 caviomorph rodents, DNA sequencing analyses allowed the identification of 4 species of the subgenus L. (Viannia): L. shawi, L. guyanensis, L. naiffi, and L. braziliensis; and 1 species of the subgenus L. (Leishmania): L. infantum. These include the description of parasite species in areas not previously included in their known distribution: L. shawi in Thrichomys inermis from Northeastern Brazil and L. naiffi in T. fosteri from Western Brazil. From the four other positive rodents, two were positive for HSP70 (234) targeting but did not generate sequences that enabled the species identification, and another two were positive only in kDNA targeting. Conclusions/Significance The infection rate demonstrated by the serology (51.3%) points out that the natural Leishmania infection in caviomorph rodents is much higher than that observed in the molecular diagnosis (4.6%), highlighting that, in terms of the host species responsible for maintaining Leishmania species in the wild, our current knowledge represents only the

  10. Distribution and Room Air Mixing Risks to Retrofitted Homes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burdick, A.

    2014-12-01

    An energy efficiency upgrade reduces a home’s heating and cooling load. If the load reduction is great enough and the heating, ventilation, and air conditioning system warrants replacement, that system is often upgraded with a more efficient, lower capacity system that meets the load of the upgraded house. For a single-story house with floor supply air diffusers, the ducts often are removed and upgraded. For houses with ducts that are embedded in walls, the cost of demolition precludes the replacement of ducts. The challenge with the use of existing ducts is that the reduced airflow creates a decreased throw atmore » the supply registers, and the supply air and room air do not mix well, leading to potential thermal comfort complaints. This project investigates this retrofit scenario. The issues and solutions discussed here are relevant to all climate zones, with emphasis on climates that require cooling. In this project, IBACOS performed load calculations for a two-story 1960s house and characterized duct sizes and layouts based on industry “rules of thumb” (Herk et al. 2014). The team performed duct-sizing calculations for unaltered ducts and post-retrofit airflows and examined airflow velocities and pressure changes with respect to various factors. The team then used a mocked-up duct and register setup to measure the characteristics of isothermal air—to reduce the effects of buoyancy from the observations—passing through the duct and leaving the register.« less

  11. Recognition and management of rodent-borne infectious disease outbreaks after heavy rainfall and flooding.

    PubMed

    Diaz, James H

    2014-01-01

    Climatic events, especially heavy rains and flooding following periods of relative drought, have precipitated both arthropod-borne and rodent-borne infectious disease outbreaks. Heavy rainfall encourages excessive wild grass seed production that supports increased outdoor rodent populations, and flooding forces rodents from their burrows near water sources into the built environment and closer to humans. The objectives of this review are to alert clinicians to the climatic conditions common to hurricane-prone regions, such as Louisiana, that can precipitate outbreaks of the two rodent-borne diseases most often associated with periods of heavy rainfall and flooding, leptospirosis (LS) and hantavirus pulmonary syndrome (HPS). It will also describe the epidemiology, presenting clinical manifestations and outcomes of these rodent-borne infectious diseases, and recommend both prophylactic therapies and effective control and prevention strategies for rodent-borne infectious disease outbreaks. Healthcare providers should maintain high levels of suspicion for LS in patients developing febrile illnesses after contaminated freshwater exposures during flooding or recreational events, and for HPS in patients with febrile illnesses that progress rapidly to respiratory failure following rodent exposures in enclosed spaces. Public health educational strategies should encourage limiting human contact with all wild and peridomestic rats and mice, avoiding all contact with rodent excreta, safely disposing of all rodent excreta, and modifying the built environment to deter rodents from colonizing households and workplaces.

  12. Application of Synchrotron Microprobe Methods to Solid-Phase Speciation of Metals and Metalloids in House Dust

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    S Walker; H Jamieson; P Rasmussen

    2011-12-31

    Determination of the source and form of metals in house dust is important to those working to understand human and particularly childhood exposure to metals in residential environments. We report the development of a synchrotron microprobe technique for characterization of multiple metal hosts in house dust. We have applied X-ray fluorescence for chemical characterization and X-ray diffraction for crystal structure identification using microfocused synchrotron X-rays at a less than 10 {micro}m spot size. The technique has been evaluated by application to archived house dust samples containing elevated concentrations of Pb, Zn, and Ba in bedroom dust, and Pb and Asmore » in living room dust. The technique was also applied to a sample of soil from the corresponding garden to identify linkages between indoor and outdoor sources of metals. Paint pigments including white lead (hydrocerussite) and lithopone (wurtzite and barite) are the primary source of Pb, Zn, and Ba in bedroom dust, probably related to renovation activity in the home at the time of sampling. The much lower Pb content in the living room dust shows a relationship to the exterior soil and no specific evidence of Pb and Zn from the bedroom paint pigments. The technique was also successful at confirming the presence of chromated copper arsenate treated wood as a source of As in the living room dust. The results of the study have confirmed the utility of this approach in identifying specific metal forms within the dust.« less

  13. Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis

    PubMed Central

    Ben-Eliezer, Daniel; Yechiam, Eldad

    2016-01-01

    Considered an antidepressant and anti-anxiety agent, Hypericum perforatum affects multiple neurotransmitters in a non-competitive synergistic manner, and may have nootropic potential. We quantitatively reviewed the pre-clinical literature to examine if there is a cognitive-enhancing effect of H. perforatum in healthy rodents. Additionally, within these studies, we compared the effects observed in intact rodents versus those whose performance has been impaired, mostly through stress manipulations. The meta-analysis incorporated studies that examined the effect of H. perforatum versus placebo on memory indices of task performance. All analyses were based on weighting different studies according to their inverse variance. Thirteen independent studies (published 2000–2014) involving 20 experimental comparisons met our inclusion criteria. The results showed a large positive effect of H. perforatum on cognitive performance for intact, healthy rodents (d = 1.11), though a larger effect emerged for stress-impaired rodents (d = 3.10 for restraint stress). The positive effect on intact rodents was observed in tasks assessing reference memory as well as working memory, and was not moderated by the type of memory or motivation (appetitive versus aversive). Thus, while primarily considered as a medication for depression, H. perforatum shows considerable nootropic potential in rodents. PMID:27762349

  14. Joshua tree (Yucca brevifolia) seeds are dispersed by seed-caching rodents

    USGS Publications Warehouse

    Vander Wall, S.B.; Esque, T.; Haines, D.; Garnett, M.; Waitman, B.A.

    2006-01-01

    Joshua tree (Yucca brevifolia) is a distinctive and charismatic plant of the Mojave Desert. Although floral biology and seed production of Joshua tree and other yuccas are well understood, the fate of Joshua tree seeds has never been studied. We tested the hypothesis that Joshua tree seeds are dispersed by seed-caching rodents. We radioactively labelled Joshua tree seeds and followed their fates at five source plants in Potosi Wash, Clark County, Nevada, USA. Rodents made a mean of 30.6 caches, usually within 30 m of the base of source plants. Caches contained a mean of 5.2 seeds buried 3-30 nun deep. A variety of rodent species appears to have prepared the caches. Three of the 836 Joshua tree seeds (0.4%) cached germinated the following spring. Seed germination using rodent exclosures was nearly 15%. More than 82% of seeds in open plots were removed by granivores, and neither microsite nor supplemental water significantly affected germination. Joshua tree produces seeds in indehiscent pods or capsules, which rodents dismantle to harvest seeds. Because there is no other known means of seed dispersal, it is possible that the Joshua tree-rodent seed dispersal interaction is an obligate mutualism for the plant.

  15. Are Synonymous Sites in Primates and Rodents Functionally Constrained?

    PubMed

    Price, Nicholas; Graur, Dan

    2016-01-01

    It has been claimed that synonymous sites in mammals are under selective constraint. Furthermore, in many studies the selective constraint at such sites in primates was claimed to be more stringent than that in rodents. Given the larger effective population sizes in rodents than in primates, the theoretical expectation is that selection in rodents would be more effective than that in primates. To resolve this contradiction between expectations and observations, we used processed pseudogenes as a model for strict neutral evolution, and estimated selective constraint on synonymous sites using the rate of substitution at pseudosynonymous and pseudononsynonymous sites in pseudogenes as the neutral expectation. After controlling for the effects of GC content, our results were similar to those from previous studies, i.e., synonymous sites in primates exhibited evidence for higher selective constraint that those in rodents. Specifically, our results indicated that in primates up to 24% of synonymous sites could be under purifying selection, while in rodents synonymous sites evolved neutrally. To further control for shifts in GC content, we estimated selective constraint at fourfold degenerate sites using a maximum parsimony approach. This allowed us to estimate selective constraint using mutational patterns that cause a shift in GC content (GT ↔ TG, CT ↔ TC, GA ↔ AG, and CA ↔ AC) and ones that do not (AT ↔ TA and CG ↔ GC). Using this approach, we found that synonymous sites evolve neutrally in both primates and rodents. Apparent deviations from neutrality were caused by a higher rate of C → A and C → T mutations in pseudogenes. Such differences are most likely caused by the shift in GC content experienced by pseudogenes. We conclude that previous estimates according to which 20-40% of synonymous sites in primates were under selective constraint were most likely artifacts of the biased pattern of mutation.

  16. 16. CELLAR, UNDER WEST MEETING ROOM, LOOKING SOUTHEAST. Discarded marble ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. CELLAR, UNDER WEST MEETING ROOM, LOOKING SOUTHEAST. Discarded marble range top incorporated into a low brick partition. It is possible the range originally stood between the two brick walls beyond to the right. There appears to be a bricked-up fire box opening in the far wall. The fragments of the marble range top have been catalogued into the Architectural Study Collection of Independence National Historical Park. Dimensions recorded in Field Records. - Twelfth Street Meeting House, 20 South Twelfth Street, Philadelphia, Philadelphia County, PA

  17. The Revised Neurobehavioral Severity Scale (NSS-R) for Rodents.

    PubMed

    Yarnell, Angela M; Barry, Erin S; Mountney, Andrea; Shear, Deborah; Tortella, Frank; Grunberg, Neil E

    2016-04-08

    Motor and sensory deficits are common following traumatic brain injury (TBI). Although rodent models provide valuable insight into the biological and functional outcomes of TBI, the success of translational research is critically dependent upon proper selection of sensitive, reliable, and reproducible assessments. Published literature includes various observational scales designed to evaluate post-injury functionality; however, the heterogeneity in TBI location, severity, and symptomology can complicate behavioral assessments. The importance of choosing behavioral outcomes that can be reliably and objectively quantified in an efficient manner is becoming increasingly important. The Revised Neurobehavioral Severity Scale (NSS-R) is a continuous series of specific, sensitive, and standardized observational tests that evaluate balance, motor coordination, and sensorimotor reflexes in rodents. The tasks follow a specific order designed to minimize interference: balance, landing, tail raise, dragging, righting reflex, ear reflex, eye reflex, sound reflex, tail pinch, and hindpaw pinch. The NSS-R has proven to be a reliable method differentiating brain-injured rodents from non-brain-injured rodents across many brain injury models. Copyright © 2016 John Wiley & Sons, Inc.

  18. National Space Council Meeting from the White House

    NASA Image and Video Library

    2018-06-18

    NASA Administrator Jim Bridenstine attends the third meeting of the National Space Council in the East Room of the White House, Monday, June 18, 2018, in Washington. President Trump kicked off the meeting by signing Space Policy Directive-3, which directs the U.S. to lead space traffic management and mitigate the effects of space debris. Vice President Mike Pence led the meeting, joined by other government officials. Administrator Bridenstine reported on NASA's progress in implementing Space Policy Directive-1, which directs NASA to return astronauts to the Moon and eventually send humans to Mars.

  19. SEXUAL BEHAVIOR IN MALE RODENTS

    PubMed Central

    Hull, Elaine M.; Dominguez, Juan M.

    2007-01-01

    The hormonal factors and neural circuitry that control copulation are similar across rodent species, although there are differences in specific behavior patterns. Both estradiol (E) and dihydrotestosterone (DHT) contribute to the activation of mating, although E is more important for copulation and DHT, for genital reflexes. Hormonal activation of the medial preoptic area (MPOA) is most effective, although implants in the medial amygdala (MeA) can also stimulate mounting in castrates. Chemosensory inputs from the main and accessory olfactory systems are the most important stimuli for mating in rodents, especially in hamsters, although genitosensory input also contributes. Dopamine agonists facilitate sexual behavior, and serotonin (5-HT) is generally inhibitory, though certain 5-HT receptor subtypes facilitate erection or ejaculation. Norepinephrine agonists and opiates have dose-dependent effects, with low doses facilitating and high doses inhibiting behavior. PMID:17499249

  20. Gait Analysis Methods for Rodent Models of Arthritic Disorders: Reviews and Recommendations

    PubMed Central

    Lakes, Emily H.; Allen, Kyle D.

    2016-01-01

    Gait analysis is a useful tool to understand behavioral changes in preclinical arthritis models. While observational scoring and spatiotemporal gait parameters are the most widely performed gait analyses in rodents, commercially available systems can now provide quantitative assessments of spatiotemporal patterns. However, inconsistencies remain between testing platforms, and laboratories often select different gait pattern descriptors to report in the literature. Rodent gait can also be described through kinetic and kinematic analyses, but systems to analyze rodent kinetics and kinematics are typically custom made and often require sensitive, custom equipment. While the use of rodent gait analysis rapidly expands, it is important to remember that, while rodent gait analysis is a relatively modern behavioral assay, the study of quadrupedal gait is not new. Nearly all gait parameters are correlated, and a collection of gait parameters is needed to understand a compensatory gait pattern used by the animal. As such, a change in a single gait parameter is unlikely to tell the full biomechanical story; and to effectively use gait analysis, one must consider how multiple different parameters contribute to an altered gait pattern. The goal of this article is to review rodent gait analysis techniques and provide recommendations on how to use these technologies in rodent arthritis models, including discussions on the strengths and limitations of observational scoring, spatiotemporal, kinetic, and kinematic measures. Recognizing rodent gait analysis is an evolving tool, we also provide technical recommendations we hope will improve the utility of these analyses in the future. PMID:26995111

  1. Evaluating social defeat as a model for psychopathology in adult female rodents.

    PubMed

    Solomon, Matia B

    2017-01-02

    Social conflict is a predominant stressor in humans and is associated with increased risk for developing psychological illnesses including depression and anxiety. Overwhelmingly, more women suffer from these disorders, which may be due to increased stress sensitivity. Like humans, rodents experience a myriad of physiological and behavioral sequelae due to prolonged stress exposure. Although the motivation for social conflict may differ between humans and rodents, female rodents may provide an opportunity to explore the underlying mechanisms by which stress confers risk for psychopathology in women. Because most female rodents do not express spontaneous aggression, the majority of basic research examines the physiological and behavioral outcomes of social conflict in male rodents. However, there are instances where female rodents exhibit territorial (California mice and Syrian hamsters) and maternal aggression (rats, mice, and hamsters) creating a venue to examine sex differences in physiology and behavior in response to stress. While many studies rely upon nonsocial behavioral assays (e.g., elevated plus maze, forced swim test) to assess the impact of stress on emotionality, here we primarily focus on behavioral outcomes in social-based assays in rodents. This is critically important given that disruptions in social relationships can be a cause and consequence of neuropsychiatric diseases. Next, we briefly discuss how sex differences in the recruitment of neural circuitry and/or neurochemistry in response to stress may underlie sex differences in neuroendocrine and behavioral stress responses. Finally, the translational value of females in rodent stress models and considerations regarding behavioral interpretations of these models are discussed. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  2. 75 FR 4100 - Affirmative Fair Housing, Marketing (AFHM) Plan-Multifamily Housing, Affirmative Fair Housing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-26

    ..., Marketing (AFHM) Plan-Multifamily Housing, Affirmative Fair Housing Marketing (AFHM) Plan-Single Family Housing and Affirmative Fair Housing Marketing (AFHM) Plan- Cooperatives/Condominiums AGENCY: Office of... for marketing to ensure that they meet the Fair Housing guidelines concerning the manner in which...

  3. First Isolates of Leptospira spp., from Rodents Captured in Angola

    PubMed Central

    Fortes-Gabriel, Elsa; Carreira, Teresa; Vieira, Maria Luísa

    2016-01-01

    Rodents play an important role in the transmission of pathogenic Leptospira spp. However, in Angola, neither the natural reservoirs of these spirochetes nor leptospirosis diagnosis has been considered. Regarding this gap, we captured rodents in Luanda and Huambo provinces to identify circulating Leptospira spp. Rodent kidney tissue was cultured and DNA amplified and sequenced. Culture isolates were evaluated for pathogenic status and typing with rabbit antisera; polymerase chain reaction (PCR) and sequencing were also performed. A total of 37 rodents were captured: Rattus rattus (15, 40.5%), Rattus norvegicus (9, 24.3%), and Mus musculus (13, 35.2%). Leptospiral DNA was amplified in eight (21.6%) kidney samples. From the cultures, we obtained four (10.8%) Leptospira isolates belonging to the Icterohaemorrhagiae and Ballum serogroups of Leptospira interrogans and Leptospira borgpetersenii genospecies, respectively. This study provides information about circulating leptospires spread by rats and mice in Angola. PMID:26928840

  4. A Comparative Study of the Traditional Houses Kaili and Bugis-Makassar in Indonesia

    NASA Astrophysics Data System (ADS)

    Suharto, M. F.; Kawet, R. S. S. I.; Tumanduk, M. S. S. S.

    2018-02-01

    In this study, I compared the physical elements of two Indonesian traditional houses between a Kaili tribe (Central Sulawesi) and a Bugis-Makassar tribe (South Sulawesi). If we viewed of the name, meaning and function from both traditional houses have similarities, namely the Souraja/Saoraja house (House of the King), however, observed more detail the physical elements of architecture also show the differences. The spatial, physical and stylistic systems (N. John Habraken’s theory) were applied to analyze their differences and the similarities of the physical elements of architecture on those two traditional houses. The results of the analysis identified that the physical elements of architecture such as the orientation, the function and distribution of rooms (the spatial system), the constructions and materials of floor, wall and roof (the physical system) and the opening types of the door and window as well as ornaments used showed similarities. Meanwhile the physical elements of architecture such as the arrangement of columns, form and spatial pattern as well as the placement of the stairs (the spatial system), the constructions and materials of foundation, column and beam (the physical system) as well as the form of the roof and façade found differences of both traditional houses.

  5. Rodent carcinogens: Setting priorities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gold, L.S.; Slone, T.H.; Stern, B.R.

    1992-10-09

    The human diet contains an enormous background of natural chemicals, such as plant pesticides and the products of cooking, that have not been a focus of carcinogenicity testing. A broadened perspective that includes these natural chemicals is necessary. A comparison of possible hazards for 80 daily exposures to rodent carcinogens from a variety of sources is presented, using an index (HERP) that relates human exposure to carcinogenic potency in rodents. A similar ordering would be expected with the use of standard risk assessment methodology for the same human exposure values. Results indicate that, when viewed against the large background ofmore » naturally occurring carcinogens in typical portions of common foods, the residues of synthetic pesticides or environmental pollutants rank low. A similar result is obtained in a separate comparison of 32 average daily exposures to natural pesticides and synthetic pesticides residues in the diet. Although the findings do not indicate that these natural dietary carcinogens are important in human cancer, they cast doubt on the relative importance for human cancer of low-dose exposures to synthetic chemicals.« less

  6. A glimpse on the pattern of rodent diversification: a phylogenetic approach

    PubMed Central

    2012-01-01

    Background Development of phylogenetic methods that do not rely on fossils for the study of evolutionary processes through time have revolutionized the field of evolutionary biology and resulted in an unprecedented expansion of our knowledge about the tree of life. These methods have helped to shed light on the macroevolution of many taxonomic groups such as the placentals (Mammalia). However, despite the increase of studies addressing the diversification patterns of organisms, no synthesis has addressed the case of the most diversified mammalian clade: the Rodentia. Results Here we present a rodent maximum likelihood phylogeny inferred from a molecular supermatrix. It is based on 11 mitochondrial and nuclear genes that covers 1,265 species, i.e., respectively 56% and 81% of the known specific and generic rodent diversity. The inferred topology recovered all Rodentia clades proposed by recent molecular works. A relaxed molecular clock dating approach provided a time framework for speciation events. We found that the Myomorpha clade shows a greater degree of variation in diversification rates than Sciuroidea, Caviomorpha, Castorimorpha and Anomaluromorpha. We identified a number of shifts in diversification rates within the major clades: two in Castorimorpha, three in Ctenohystrica, 6 within the squirrel-related clade and 24 in the Myomorpha clade. The majority of these shifts occurred within the most recent familial rodent radiations: the Cricetidae and Muridae clades. Using the topological imbalances and the time line we discuss the potential role of different diversification factors that might have shaped the rodents radiation. Conclusions The present glimpse on the diversification pattern of rodents can be used for further comparative meta-analyses. Muroid lineages have a greater degree of variation in their diversification rates than any other rodent group. Different topological signatures suggest distinct diversification processes among rodent lineages. In

  7. Fluorescence detection of protein content in house dust: the possible role of keratin.

    PubMed

    Voloshina, O V; Shirshin, E A; Lademann, J; Fadeev, V V; Darvin, M E

    2017-03-01

    We propose a fluorescence method for protein content assessment in fine house dust, which can be used as an indicator of the hygienic state of occupied rooms. The results of the measurements performed with 30 house dust samples, including ultrafiltration experiments, strongly suggest that the fluorescence emission of house dust extracts excited at 350 nm is mainly due to protein fragments, which are presumably keratin hydrolysates. This suggestion is supported by several facts: (i) Spectral band shapes for all the samples under investigation are close and correspond to that of keratin; (ii) fluorescence intensity correlates with the total protein content as provided by Lowry assay; (iii) treatment of the samples with proteinase K, which induces keratin hydrolysis, results in fluorescence enhancement without changing fluorescence band shape; and (iv) Raman spectra of keratin and fine house dust samples exhibit a very similar structure. Based on the obtained results and literature data, we propose a hypothesis that keratin is a major substrate for fluorescence species in fine house dust, which are responsible for emission at 350-nm excitation. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  8. Molecular Survey of Zoonotic Agents in Rodents and Other Small Mammals in Croatia

    PubMed Central

    Tadin, Ante; Tokarz, Rafal; Markotić, Alemka; Margaletić, Josip; Turk, Nenad; Habuš, Josipa; Svoboda, Petra; Vucelja, Marko; Desai, Aaloki; Jain, Komal; Ian Lipkin, W.

    2016-01-01

    Croatia is a focus for many rodent-borne zoonosis. Here, we report a survey of 242 rodents and small mammals, including 43 Myodes glareolus, 131 Apodemus flavicollis, 53 Apodemus agrarius, three Apodemus sylvaticus, six Sorex araneus, four Microtus arvalis, one Microtus agrestis, and one Muscardinus avellanarius, collected at eight sites in Croatia over an 8-year period. Multiplex MassTag polymerase chain reaction (PCR) was used for detection of Borrelia, Rickettsia, Bartonella, Babesia, Ehrlichia, Anaplasma, Francisella tularensis, and Coxiella burnetii. Individual PCR assays were used for detection of Leptospira, lymphocytic choriomeningitis virus, orthopoxviruses, flaviviruses, hantaviruses, and Toxoplasma gondii. Of the rodents, 52 (21.5%) were infected with Leptospira, 9 (3.7%) with Borrelia miyamotoi, 5 (2%) with Borrelia afzelii, 29 (12.0%) with Bartonella, 8 (3.3%) with Babesia microti, 2 (0.8%) with Ehrlichia, 4 (1.7%) with Anaplasma, 2 (0.8%) with F. tularensis, 43 (17.8%) with hantaviruses, and 1 (0.4%) with an orthopoxvirus. Other agents were not detected. Multiple infections were found in 32 rodents (13.2%): dual infections in 26 rodents (10.7%), triple infections in four rodents (2.9%), and quadruple infections in two rodents (0.8%). Our findings indicate that rodents in Croatia harbor a wide range of bacteria and viruses that are pathogenic to humans. PMID:26711522

  9. A scale value for the balance between stage and pit and inside an historical opera house

    NASA Astrophysics Data System (ADS)

    Prodi, Nicola; Velecka, Sylvia

    2004-05-01

    Despite its recognized importance, the balance between the singer and the orchestra inside an opera house has received minor attention in the past. In fact, after the fundamental work of Meyer [J. Meyer, ``Some problems of opera house acoustics,'' Proceedings of 12th I.C.A., Vancouver, 1986, pp. 13-18], who explained why the solo singing voice can compete with the orchestra, only partial results were reported on this perceived attribute. In this work a reference scale to assess the balance inside an historical opera house is achieved by means of listening tests inside a controlled room. Two scaling experiments were performed based on the acoustical data measured inside an historical opera house, the Teatro Comunale di Ferrara, Italy. By doing so all of the relevant acoustical characteristics of a typical Italian-style opera house could be exactly reproduced. Acceptable values do not differ much in the stalls and in the boxes and are within 2 dB(A) to +2.3 dB(A). The transfer of the findings to other types of opera houses is discussed, too.

  10. Risk Factors for Mosquito House Entry in the Lao PDR

    PubMed Central

    Hiscox, Alexandra; Khammanithong, Phasouk; Kaul, Surinder; Sananikhom, Pany; Luthi, Ruedi; Brey, Paul T.; Lindsay, Steve W.

    2013-01-01

    Background Construction of the Nam Theun 2 hydroelectric project and flooding of a 450 km2 area of mountain plateau in south-central Lao PDR resulted in the resettlement of 6,300 people to newly built homes. We examined whether new houses would have altered risk of house entry by mosquitoes compared with traditional homes built from poorer construction materials. Methodology/Principal Findings Surveys were carried out in the Nam Theun 2 resettlement area and a nearby traditional rice farming area in 2010. Mosquitoes were sampled in bedrooms using CDC light traps in 96 resettlement houses and 96 traditional houses and potential risk factors for mosquito house entry were recorded. Risk of mosquito house entry was more than twice as high in traditional bamboo houses compared with those newly constructed from wood (Putative Japanese Encephalitis (JE) vector incidence rate ratio (IRR) = 2.26, 95% CI 1.38–3.70, P = 0.001; Anopheline IRR = 2.35, 95% CI: 1.30–4.23, P = 0.005). Anophelines were more common in homes with cattle compared against those without (IRR = 2.32, 95% CI: 1.29–4.17, P = 0.005).Wood smoke from cooking fires located under the house or indoors was found to be protective against house entry by both groups of mosquito, compared with cooking in a separate room beside the house (Putative JE vector IRR = 0.43, 95% CI: 0.26–0.73, P = 0.002; Anopheline IRR = 0.22, 95% CI: 0.10–0.51, P<0.001). Conclusions/Significance Construction of modern wooden homes should help reduce human-mosquito contact in the Lao PDR. Reduced mosquito contact rates could lead to reduced transmission of diseases such as JE and malaria. Cattle ownership was associated with increased anopheline house entry, so zooprophylaxis for malaria control is not recommended in this area. Whilst wood smoke was protective against putative JE vector and anopheline house entry we do not recommend indoor cooking since smoke inhalation can enhance respiratory

  11. Toxoplasmosis seroprevalence in urban rodents: a survey in Niamey, Niger

    PubMed Central

    Mercier, Aurélien; Garba, Madougou; Bonnabau, Henri; Kane, Mamadou; Rossi, Jean-Pierre; Dardé, Marie-Laure; Dobigny, Gauthier

    2013-01-01

    A serological survey of Toxoplasma gondii was conducted on 766 domestic and peridomestic rodents from 46 trapping sites throughout the city of Niamey, Niger. A low seroprevalence was found over the whole town with only 1.96% of the rodents found seropositive. However, differences between species were important, ranging from less than 2% in truly commensal Mastomys natalensis, Rattus rattus and Mus musculus, while garden-associated Arvicanthis niloticus displayed 9.1% of seropositive individuals. This is in line with previous studies on tropical rodents - that we reviewed here - which altogether show that Toxoplasma seroprevalence in rodent is highly variable, depending on many factors such as locality and/or species. Moreover, although we were not able to decipher statistically between habitat or species effect, such a contrast between Nile grass rats and the other rodent species points towards a potentially important role of environmental toxoplasmic infection. This would deserve to be further scrutinised since intra-city irrigated cultures are extending in Niamey, thus potentially increasing Toxoplasma circulation in this yet semi-arid region. As far as we are aware of, our study is one of the rare surveys of its kind performed in Sub-Saharan Africa and the first one ever conducted in the Sahel. PMID:23828008

  12. Road traffic noise and hypertension--accounting for the location of rooms.

    PubMed

    Babisch, Wolfgang; Wölke, Gabriele; Heinrich, Joachim; Straff, Wolfgang

    2014-08-01

    The association between the exposure to road traffic noise and the prevalence of hypertension was assessed accounting for background air pollution and the location of rooms with respect to the road. A cross-sectional study was carried out inviting all subjects aged 35-74 years for participation that lived on 7 major trunk roads in 3-4 storey terraced apartment buildings and in parallel side streets that were completely shielded from noise due to the rows of houses along the major roads. The study was performed on 1770 subjects that did not have a self-reported medical doctor diagnosis of hypertension before they moved into their current residence. Noise levels at the facade of the front and the rear side of the houses were drawn from available noise maps of the area. A large set of covariates were considered to adjust the results for confounding. Significant increases between road traffic noise and hypertension were found with respect to the 24h A-weighted average noise indicator L(DEN). The adjusted odds ratio (OR) per noise level increment of 10 dB(A) was 1.11 (95% confidence interval (CI): 1.00-1.23). Stronger significant estimates of the noise effect were found in subjects with long residence time (OR=1.20, CI=1.05-1.37), and with respect to the exposure of the living room during daytime (OR=1.24, CI=1.08-1.41) compared with the exposure of the bedroom during night-time (OR=0.91, CI=0.78-1.06). Chronic exposure to road traffic noise is associated with an increased risk of high blood pressure. Daytime noise exposure of the living room had a stronger impact on the association than night-time exposure of the bedroom. Copyright © 2014 Elsevier Inc. All rights reserved.

  13. Significant reduction in indoor radon in newly built houses.

    PubMed

    Finne, Ingvild E; Kolstad, Trine; Larsson, Maria; Olsen, Bård; Prendergast, Josephine; Rudjord, Anne Liv

    2018-02-15

    Results from two national surveys of radon in newly built homes in Norway, performed in 2008 and 2016, were used in this study to investigate the effect of the 2010 building regulations introducing limit values on radon and requirements for radon prevention measures upon construction of new buildings. In both surveys, homes were randomly selected from the National Building Registry. The overall result was a considerable reduction of radon concentrations after the implementation of new regulations, but the results varied between the different dwelling categories. A statistically significant reduction was found for detached houses where the average radon concentration was almost halved from 76 to 40 Bq/m 3 . The fraction of detached houses which had at least one frequently occupied room with a radon concentration above the Action Level (100 Bq/m 3 ) fell from 23.9% to 6.4%, while the fraction above the Upper Limit Value (200 Bq/m 3 ) was reduced from 7.6% to 2.5%. In 2008 the average radon concentration measured in terraced and semi-detached houses was 44 and in 2016 it was 29 Bq/m 3 , but the reduction was not statistically significant. For multifamily houses, it was not possible to draw a conclusion due to insufficient number of measurements. Copyright © 2018 Elsevier Ltd. All rights reserved.

  14. Responses of nocturnal rodents to shrub encroachment in Banni grasslands, Gujarat, India

    NASA Astrophysics Data System (ADS)

    Jayadevan, A.

    2016-12-01

    Shrub encroachment is one of the greatest threats to grasslands globally. These woodlands can strongly influence the behaviour of small mammals adapted to more open habitats, which rely on high visibility for early detection of predators. In semi-arid grasslands, rodents are considered keystone species. Although shrub encroachment is known to negatively affect rodent assemblages, its impact on the foraging behaviour of rodents, which is known to vary in response to risky situations, is unknown. Understanding whether shrub encroachment alters such antipredator behaviour is important as antipredator behaviour can alter the distribution, abundance and ultimately, survival of prey species. In this study, I explored the effects of shrub encroachment on the foraging behaviour of nocturnal rodent communities in the Banni grasslands, India. I examined foraging behaviour, quantified using the giving-up density (GUD) framework and the number of rodent crossings around food patches, in two habitats that differed in the extent of shrub encroachment. Under the GUD framework, the amount of food left behind by a forager in a food patch reflects the costs of feeding at the patch. Higher GUDs imply higher foraging costs. I also investigated how removal of an invasive woody plant, Prosopis juliflora would affect foraging behaviour of nocturnal rodents. High shrub encroachment was associated with higher foraging costs (higher GUDs) and lower activity than the sparsely wooded habitat, likely due to low visibility in the densely wooded habitat. The dense habitat also supported a higher richness and relative abundance of generalist rodents than the sparse habitat, likely due to the increased heterogeneity of the habitat. The tree removal experiment revealed that rodents had lower GUDs (i.e., low foraging costs) after the event of tree cutting. This may be due to the reduction of cover in the habitat, leading to higher visibility and lower predation risk. My results suggest that shrub

  15. Nutritional Evaluation of NASA's Rodent Food Bar Diet

    NASA Technical Reports Server (NTRS)

    Barrett, Joyce E.; Yu, Diane S.; Dalton, Bonnie P.

    2000-01-01

    Tests are being conducted on NASA's rodent Food Bar in preparation for long-term use as the rat and mouse diet aboard the International Space Station. Nutritional analyses are performed after the bars are manufactured and then repeated periodically to determine nutritional stability. The primary factors analyzed are protein, ash, fat, fiber, moisture, amino acids, fatty acids, and minerals. Nutrient levels are compared to values published in the National Research Council's dietary requirements for rodents, and also to those contained in several commonly used commercial rodent lab diets. The Food Bar is manufactured from a powdered diet to which moisture is added as it is processed through an extruder. The bars are dipped into potassium sorbate, vacuum-sealed, and irradiated. In order to determine nutrient changes during extrusion and irradiation, the powdered diet, the non-irradiated bars, and the irradiated bars are all analyzed. We have observed lower values for some nutrients (iodine, vitamin K, and iron) in the Food Bars compared with NRC requirements. Many nutrients in the Food Bars are contained at a higher level than levels in the NRC requirements. An additional factor we are investigating is the 26% moisture level in the Food Bars, which drops to about 15% within a week, compared to a stable 10% moisture in many standard lab chow diets. In addition to the nutritional analyses, the food bar is being fed to several strains of rats and mice, and feeding study and necropsy results are being observed (Barrett et al, unpublished data). Information from the nutritional analyses and from the rodent studies will enable us to recommend the formulation that will most adequately meet the rodent Food Bar requirements for long-term use aboard the Space Station.

  16. Ecomorphological analysis of the astragalo-calcaneal complex in rodents and inferences of locomotor behaviours in extinct rodent species

    PubMed Central

    Hautier, Lionel; Marivaux, Laurent; Vianey-Liaud, Monique

    2016-01-01

    Studies linking postcranial morphology with locomotion in mammals are common. However, such studies are mostly restricted to caviomorphs in rodents. We present here data from various families, belonging to the three main groups of rodents (Sciuroidea, Myodonta, and Ctenohystrica). The aim of this study is to define morphological indicators for the astragalus and calcaneus, which allow for inferences to be made about the locomotor behaviours in rodents. Several specimens were dissected and described to bridge the myology of the leg with the morphology of the bones of interest. Osteological characters were described, compared, mechanically interpreted, and correlated with a “functional sequence” comprising six categories linked to the lifestyle and locomotion (jumping, cursorial, generalist, fossorial, climber and semi-aquatic). Some character states are typical of some of these categories, especially arboreal climbers, fossorial and “cursorial-jumping” taxa. Such reliable characters might be used to infer locomotor behaviours in extinct species. Linear discriminant analyses (LDAs) were used on a wider sample of species and show that astragalar and calcaneal characters can be used to discriminate the categories among extant species whereas a posteriori inferences on extinct species should be examined with caution. PMID:27761303

  17. The hip adductor muscle group in caviomorph rodents: anatomy and homology.

    PubMed

    García-Esponda, César M; Candela, Adriana M

    2015-06-01

    Anatomical comparative studies including myological data of caviomorph rodents are relatively scarce, leading to a lack of use of muscular features in cladistic and morphofunctional analyses. In rodents, the hip adductor muscles constitute an important group of the hindlimb musculature, having an important function during the beginning of the stance phase. These muscles are subdivided in several distinct ways in the different clades of rodents, making the identification of their homologies hard to establish. In this contribution we provide a detailed description of the anatomical variation of the hip adductor muscle group of different genera of caviomorph rodents and identify the homologies of these muscles in the context of Rodentia. On this basis, we identify the characteristic pattern of the hip adductor muscles in Caviomorpha. Our results indicate that caviomorphs present a singular pattern of the hip adductor musculature that distinguishes them from other groups of rodents. They are characterized by having a single m. adductor brevis that includes solely its genicular part. This muscle, together with the m. gracilis, composes a muscular sheet that is medial to all other muscles of the hip adductor group. Both muscles probably have a synergistic action during locomotion, where the m. adductor brevis reinforces the multiple functions of the m. gracilis in caviomorphs. Mapping of analyzed myological characters in the context of Rodentia indicates that several features are recovered as potential synapomorphies of caviomorphs. Thus, analysis of the myological data described here adds to the current knowledge of caviomorph rodents from anatomical and functional points of view, indicating that this group has features that clearly differentiate them from other rodents. Copyright © 2015 Elsevier GmbH. All rights reserved.

  18. Helminth Infections of Rodents and Their Zoonotic Importance in Boyer-Ahmad District, Southwestern Iran.

    PubMed

    Ranjbar, Mohammad Javad; Sarkari, Bahador; Mowlavi, Gholam Reza; Seifollahi, Zeinab; Moshfe, Abdolali; Abdolahi Khabisi, Samaneh; Mobedi, Iraj

    2017-01-01

    Rodents are considered as reservoirs of various zoonotic diseases including helminthic infections. The current study aimed to evaluate the prevalence of helminth infections in rodents, in Boyer-Ahmad district, Southwestern Iran. Overall, 52 rodents were captured from various areas of the district by Sherman live traps. The animals were then euthanized and dissected. During necropsy, each organ was examined macroscopically for presence of any cyst or visible parasite. The gastrointestinal tract was removed and their contents were evaluated for larva or adult worms. Trichinella larvae in the rodents' muscles were investigated by both digestion and pathological methods. Twenty-eight (53.8%) of the trapped rodents were male. The rodents were including 25 (48.1%) Meriones persicus , 1(1.9%) Calomyscus bailwardi , 1 (1.9%) Arvicola terresterris , 7 (13.5%) Rattus rattus , 8 (15.4%) R. norvegicus , and 10 (19.2%) Apodemus sylvaticus . Of them, 38 (73.0%) were infected with at least one helminth. Collected rodents were infected with Hymenolepis diminuta (50%), Hymenolepis nana fraterna (28.8%), Skrjabinotaenia sp. (15.4%), Anoplocephalidae sp. (15.4%), Cysticercus fasciolaris (5.8%), Trichuris muris (36.5%), Aspiculuris tetraptera (15.4%), Syphacia sp. (5.7%), Rictularia sp. (15.4%), Trichostrongylus sp. (3.8%), and Gongylonema sp. (3.8%). M. persicus was the most (84%) infected rodent, yet the differences between rodent genus and helminth infectivity were not statistically significant ( P >0.05). The rodents in Boyer-Ahmad district are infected with different helminths infections that some of them are recognized as threat to human health.

  19. Understanding arid environments using fossil rodent middens

    USGS Publications Warehouse

    Pearson, S.; Betancourt, J.L.

    2002-01-01

    American rodent middens have made a more dramatic contribution to understanding past environments and the development of ecological theory than Australian rodent middens. This relates to differences in the natural environment, the landscape histories, the scale and scientific approaches of the researchers. The comparison demonstrates: the power of synoptic perspectives; the value of thorough macrofossil identification in midden analysis and its potential advance in Australia where pollen has dominated analyses, the value of herbaria and reference collections; the potential of environmental databases; the importance of scientific history and 'critical research mass' and; finally, the opportunistic nature of palaeoecological research. ?? 2002 Elsevier Science Ltd.

  20. 23. Photocopy of ca. 1890 photograph showing DRAWING ROOM (see ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. Photocopy of ca. 1890 photograph showing DRAWING ROOM (see also PA-1524-12). Photographed during the occupancy of Dr. and Mrs. Erwin Agnew. Note the following furnishings: 1) Chandeliers, possibly by Cornelius and Sons of Philadelphia; 2) Ceiling painting at top of photocopy is copy of Guido Reni's Aurora, one of the two most popular Renaissance paintings in the mid-19th century; 3) Scagliola columns; 4) 'Turkish' upholstered chairs (typical of the period); 5) Neo-renaissance mirror at extreme left - Parry House, 1921 Arch Street, Philadelphia, Philadelphia County, PA

  1. Bone morphology of the hind limbs in two caviomorph rodents.

    PubMed

    de Araújo, F A P; Sesoko, N F; Rahal, S C; Teixeira, C R; Müller, T R; Machado, M R F

    2013-04-01

    In order to evaluate the hind limbs of caviomorph rodents a descriptive analysis of the Cuniculus paca (Linnaeus, 1766) and Hydrochoerus hydrochaeris (Linnaeus, 1766) was performed using anatomical specimens, radiography, computed tomography (CT) and full-coloured prototype models to generate bone anatomy data. The appendicular skeleton of the two largest rodents of Neotropical America was compared with the previously reported anatomical features of Rattus norvegicus (Berkenhout, 1769) and domestic Cavia porcellus (Linnaeus, 1758). The structures were analyzed macroscopically and particular findings of each species reported. Features including the presence of articular fibular projection and lunulae were observed in the stifle joint of all rodents. Imaging aided in anatomical description and, specifically in the identification of bone structures in Cuniculus paca and Hydrochoerus hydrochaeris. The imaging findings were correlated with the anatomical structures observed. The data may be used in future studies comparing these animals to other rodents and mammalian species. © 2012 Blackwell Verlag GmbH.

  2. Prevalence of Lassa virus among rodents trapped in three South-South States of Nigeria.

    PubMed

    Agbonlahor, D E; Erah, A; Agba, I M; Oviasogie, F E; Ehiaghe, A F; Wankasi, M; Eremwanarue, O A; Ehiaghe, I J; Ogbu, E C; Iyen, R I; Abbey, S; Tatfeng, M Y; Uhunmwangho, J

    2017-01-01

    Lassa fever has been endemic in Nigeria since 1969. The rodent Mastomys natalensis has been widely claimed to be the reservoir host of the Lassa virus. This study was designed to investigate the dis- tribution of species of rodents in three states (Edo, Delta and Bayelsa) of Nigeria and to determine the prevalence of Lassa virus amongst trapped rodents in the selected states. Rodents were trapped during November 2015 to October 2016 from the three states in South-South re- gion of Nigeria. Total RNA was extracted from the blood collected from the trapped rodents. Reverse transcription polymerase chain reaction (RT-PCR) was used to confirm the presence of Lassa virus in the rodents. The results revealed that six species of rodents were predominantly present in these geographical locations. Mus musculus (39.4%) had the highest prevalence, closely followed by Rattus rattus (36.1%), R. fuscipus (20.3%), M. natalensis (2%), Myosoricinae soricidae (1.2%) and R. norvegicus (1%). The overall positivity (carrier rate) of Lassa virus was 1.6% amongst the 1500 rodents caught in the three states. In Edo and Delta States, the RT-PCR results showed presence of Lassa virus in R. rattus, M. musculus and M. natalensis. On the other hand, only M. na- talensis was detected with the virus, amongst the species of rodents caught in Bayelsa State. M. natalensis recorded the highest Lassa virus among rodents trapped in Edo (87%), Delta (50%) and Bayelsa (11%) States respectively. The rather low Lassa virus positive among rodents in Bayelsa State of Nigeria may explain the absence of reports of outbreak of Lassa fever over the past 48 yr in the state. The results also confirmed that apart from Mastomys natalensis, other rodents such as Rattus rattus and Mus musculus may also serve as res- ervoirs for Lassa virus. From the findings of this cross-sectional study, it was concluded that a more comprehensive study on rodents as reservoir host, need to be undertaken across the entire states of

  3. [Small rodents in the forest ecosystem as infectious disease reservoirs].

    PubMed

    Margaletić, Josip

    2003-01-01

    Due to numerousness of populations and width of ecologic valence, small rodents are important parts of almost any forest ecosystem. The represent an important animal group, which connects primary makers with higher trophic levels. They transmit various infectious diseases dangerous for the health of people and domestic and wild animals (trichinosis, leptospirosis, tick encephalitis, Lyme disease, hemorrhagic fever with renal syndrome, etc.). The following species of small rodents live in forest ecosystems of Croatia: Chletrionomys glareolus Schreib., Arvicola terrestris L, M. subterraneus de Sel., M. arvalis Pall., M. agrestis L, M. multiplex Fat., Apodemus agrarius Pall., A. sylvaticus L. and A. flavicollis Melch. Small rodents transmit causative agents of diseases in active (excretion products) of passive (ectoparasites and endoparasites) ways. Their multiplication potential is quite high. Transmission of certain disease sometimes takes place extremely fast due to the high number of rodents, their high movability and distribution, and the fact that they easily get in touch with men and domestic and wild animals. The number of population of each species is directly influenced by abiotic and biotic factors and changes during one year and in a several year period. In a year when the influence of ecologic factors is favorable, it is presumed that the number of these rodents will significantly increase, by which the danger of their damaging effect also increases. The following factors influence the increase of a small rodent population: number and physiologic condition of the population, meteorologic conditions, habitat, food sources, natural enemies, and diseases. The occurrence of an epidemic is closely connected to the number and infectivity of causative agents. Regular control of the number of rodent population and their infectivity can help in planning preventive epidemiologic and sanitary measures to preclude the occurrence of epidemics and individual cases of

  4. Rodent Research on the International Space Station - A Look Forward

    NASA Technical Reports Server (NTRS)

    Kapusta, A. B.; Smithwick, M.; Wigley, C. L.

    2014-01-01

    Rodent Research on the International Space Station (ISS) is one of the highest priority science activities being supported by NASA and is planned for up to two flights per year. The first Rodent Research flight, Rodent Research-1 (RR-1) validates the hardware and basic science operations (dissections and tissue preservation). Subsequent flights will add new capabilities to support rodent research on the ISS. RR-1 will validate the following capabilities: animal husbandry for up to 30 days, video downlink to support animal health checks and scientific analysis, on-orbit dissections, sample preservation in RNA. Later and formalin, sample transfer from formalin to ethanol (hindlimbs), rapid cool-down and subsequent freezing at -80 of tissues and carcasses, sample return and recovery. RR-2, scheduled for SpX-6 (Winter 20142015) will add the following capabilities: animal husbandry for up to 60 days, RFID chip reader for individual animal identification, water refill and food replenishment, anesthesia and recovery, bone densitometry, blood collection (via cardiac puncture), blood separation via centrifugation, soft tissue fixation in formalin with transfer to ethanol, and delivery of injectable drugs that require frozen storage prior to use. Additional capabilities are also planned for future flights and these include but are not limited to male mice, live animal return, and the development of experiment unique equipment to support science requirements for principal investigators that are selected for flight. In addition to the hardware capabilities to support rodent research the Crew Office has implemented a training program in generic rodent skills for all USOS crew members during their pre-assignment training rotation. This class includes training in general animal handling, euthanasia, injections, and dissections. The dissection portion of this training focuses on the dissection of the spleen, liver, kidney with adrenals, brain, eyes, and hindlimbs. By achieving and

  5. Seed removal by scatter-hoarding rodents: the effects of tannin and nutrient concentration.

    PubMed

    Wang, Bo; Yang, Xiaolan

    2015-04-01

    The mutualistic interaction between scatter-hoarding rodents and seed plants have a long co-evolutionary history. Plants are believed to have evolved traits that influence the foraging behavior of rodents, thus increasing the probability of seed removal and caching, which benefits the establishment of seedlings. Tannin and nutrient content in seeds are considered among the most essential factors in this plant-animal interaction. However, most previous studies used different species of plant seeds, rendering it difficult to tease apart the relative effect of each single nutrient on rodent foraging behavior due to confounding combinations of nutrient contents across seed species. Hence, to further explore how tannin and different nutritional traits of seed affect scatter-hoarding rodent foraging preferences, we manipulated tannin, fat, protein and starch content levels, and also seed size levels by using an artificial seed system. Our results showed that both tannin and various nutrients significantly affected rodent foraging preferences, but were also strongly affected by seed size. In general, rodents preferred to remove seeds with less tannin. Fat addition could counteract the negative effect of tannin on seed removal by rodents, while the effect of protein addition was weaker. Starch by itself had no effect, but it interacted with tannin in a complex way. Our findings shed light on the effects of tannin and nutrient content on seed removal by scatter-hoarding rodents. We therefore, believe that these and perhaps other seed traits should interactively influence this important plant-rodent interaction. However, how selection operates on seed traits to counterbalance these competing interests/factors merits further study. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. Public Health Implications of Changing Rodent Importation Patterns - United States, 1999-2013.

    PubMed

    Lankau, E W; Sinclair, J R; Schroeder, B A; Galland, G G; Marano, N

    2017-04-01

    The United States imports a large volume of live wild and domestic animal species; these animals pose a demonstrated risk for introduction of zoonotic diseases. Rodents are imported for multiple purposes, including scientific research, zoo exhibits and the pet trade. Current U.S. public health regulatory restrictions specific to rodent importation pertain only to those of African origin. To understand the impacts of these regulations and the potential public health risks of international rodent trade to the United States, we evaluated live rodent import records during 1999-2013 by shipment volume and geographic origin, source (e.g. wild-caught versus captive- or commercially bred), intended purpose and rodent taxonomy. Live rodent imports increased from 2737 animals during 1999 to 173 761 animals during 2013. Increases in both the number and size of shipments contributed to this trend. The proportion of wild-captured imports declined from 75% during 1999 to <1% during 2013. Nearly all shipments during these years were imported for commercial purposes. Imports from Europe and other countries in North America experienced notable increases in volume. Gerbils and hamsters arriving from Europe and chinchillas, guinea pigs and hamsters arriving from other countries in North America were predominant taxa underlying this trend. After 2003, African-origin imports became sporadic events under the federal permit process. These patterns suggest development of large-scale captive rodent breeding markets abroad for commercial sale in the United States. While the shift from wild-captured imports alleviates many conservation concerns and risks for novel disease emergence, such consolidated sourcing might elevate exposure risks for zoonotic diseases associated with high-density rodent breeding (e.g. lymphocytic choriomeningitis or salmonellosis). A responsive border health system must periodically re-evaluate importation regulations in conjunction with key stakeholders to ensure a

  7. Rodent Species Distribution and Hantavirus Seroprevalence in Residential and Forested areas of Sarawak, Malaysia.

    PubMed

    Hamdan, Nur Elfieyra Syazana; Ng, Yee Ling; Lee, Wei Bin; Tan, Cheng Siang; Khan, Faisal Ali Anwarali; Chong, Yee Ling

    2017-01-01

    Rodents belong to the order Rodentia, which consists of three families in Borneo (i.e., Muridae, Sciuridae and Hystricidae). These include rats, mice, squirrels, and porcupines. They are widespread throughout the world and considered pests that harm humans and livestock. Some rodent species are natural reservoirs of hantaviruses (Family: Bunyaviridae) that can cause zoonotic diseases in humans. Although hantavirus seropositive human sera were reported in Peninsular Malaysia in the early 1980s, information on their infection in rodent species in Malaysia is still lacking. The rodent populations in residential and forested areas in Sarawak were sampled. A total of 108 individuals from 15 species of rodents were collected in residential ( n = 44) and forested ( n = 64) areas. The species diversity of rodents in forested areas was significantly higher (H = 2.2342) compared to rodents in residential areas (H = 0.64715) ( p < 0.001 of Zar-t test based on the Shannon index). Rattus rattus and Sundamys muelleri were present at high frequencies in both localities. An enzyme-linked immunosorbent assay (ELISA) showed that hantavirus-targeting antibodies were absent from 53 tested serum samples. This is the first report of hantavirus seroprevalence surveillance in rodent populations in Sarawak, East Malaysia. The results suggested that hantavirus was not circulating in the studied rodent populations in Sarawak, or it was otherwise at a low prevalence that is below the detection threshold. It is important to remain vigilant because of the zoonotic potential of this virus and its severe disease outcome. Further studies, such as molecular detection of viral genetic materials, are needed to fully assess the risk of hantavirus infection in rodents and humans in this region of Malaysia.

  8. Rodent Species Distribution and Hantavirus Seroprevalence in Residential and Forested areas of Sarawak, Malaysia

    PubMed Central

    Hamdan, Nur Elfieyra Syazana; Ng, Yee Ling; Lee, Wei Bin; Tan, Cheng Siang; Khan, Faisal Ali Anwarali; Chong, Yee Ling

    2017-01-01

    Rodents belong to the order Rodentia, which consists of three families in Borneo (i.e., Muridae, Sciuridae and Hystricidae). These include rats, mice, squirrels, and porcupines. They are widespread throughout the world and considered pests that harm humans and livestock. Some rodent species are natural reservoirs of hantaviruses (Family: Bunyaviridae) that can cause zoonotic diseases in humans. Although hantavirus seropositive human sera were reported in Peninsular Malaysia in the early 1980s, information on their infection in rodent species in Malaysia is still lacking. The rodent populations in residential and forested areas in Sarawak were sampled. A total of 108 individuals from 15 species of rodents were collected in residential (n = 44) and forested ( n = 64) areas. The species diversity of rodents in forested areas was significantly higher (H = 2.2342) compared to rodents in residential areas (H = 0.64715) (p < 0.001 of Zar-t test based on the Shannon index). Rattus rattus and Sundamys muelleri were present at high frequencies in both localities. An enzyme-linked immunosorbent assay (ELISA) showed that hantavirus-targeting antibodies were absent from 53 tested serum samples. This is the first report of hantavirus seroprevalence surveillance in rodent populations in Sarawak, East Malaysia. The results suggested that hantavirus was not circulating in the studied rodent populations in Sarawak, or it was otherwise at a low prevalence that is below the detection threshold. It is important to remain vigilant because of the zoonotic potential of this virus and its severe disease outcome. Further studies, such as molecular detection of viral genetic materials, are needed to fully assess the risk of hantavirus infection in rodents and humans in this region of Malaysia. PMID:28228923

  9. Visual Landmarks Facilitate Rodent Spatial Navigation in Virtual Reality Environments

    ERIC Educational Resources Information Center

    Youngstrom, Isaac A.; Strowbridge, Ben W.

    2012-01-01

    Because many different sensory modalities contribute to spatial learning in rodents, it has been difficult to determine whether spatial navigation can be guided solely by visual cues. Rodents moving within physical environments with visual cues engage a variety of nonvisual sensory systems that cannot be easily inhibited without lesioning brain…

  10. Perceptual and neural responses to sweet taste in humans and rodents.

    PubMed

    Lemon, Christian H

    2015-08-01

    This mini-review discusses some of the parallels between rodent neurophysiological and human psychophysical data concerning temperature effects on sweet taste. "Sweet" is an innately rewarding taste sensation that is associated in part with foods that contain calories in the form of sugars. Humans and other mammals can show unconditioned preference for select sweet stimuli. Such preference is poised to influence diet selection and, in turn, nutritional status, which underscores the importance of delineating the physiological mechanisms for sweet taste with respect to their influence on human health. Advances in our knowledge of the biology of sweet taste in humans have arisen in part through studies on mechanisms of gustatory processing in rodent models. Along this line, recent work has revealed there are operational parallels in neural systems for sweet taste between mice and humans, as indexed by similarities in the effects of temperature on central neurophysiological and psychophysical responses to sucrose in these species. Such association strengthens the postulate that rodents can serve as effective models of particular mechanisms of appetitive taste processing. Data supporting this link are discussed here, as are rodent and human data that shed light on relationships between mechanisms for sweet taste and ingestive disorders, such as alcohol abuse. Rodent models have utility for understanding mechanisms of taste processing that may pertain to human flavor perception. Importantly, there are limitations to generalizing data from rodents, albeit parallels across species do exist.

  11. Molecular and Paleontological Evidence for a Post-Cretaceous Origin of Rodents

    PubMed Central

    Wu, Shaoyuan; Wu, Wenyu; Zhang, Fuchun; Ye, Jie; Ni, Xijun; Sun, Jimin; Edwards, Scott V.; Meng, Jin; Organ, Chris L.

    2012-01-01

    The timing of the origin and diversification of rodents remains controversial, due to conflicting results from molecular clocks and paleontological data. The fossil record tends to support an early Cenozoic origin of crown-group rodents. In contrast, most molecular studies place the origin and initial diversification of crown-Rodentia deep in the Cretaceous, although some molecular analyses have recovered estimated divergence times that are more compatible with the fossil record. Here we attempt to resolve this conflict by carrying out a molecular clock investigation based on a nine-gene sequence dataset and a novel set of seven fossil constraints, including two new rodent records (the earliest known representatives of Cardiocraniinae and Dipodinae). Our results indicate that rodents originated around 61.7–62.4 Ma, shortly after the Cretaceous/Paleogene (K/Pg) boundary, and diversified at the intraordinal level around 57.7–58.9 Ma. These estimates are broadly consistent with the paleontological record, but challenge previous molecular studies that place the origin and early diversification of rodents in the Cretaceous. This study demonstrates that, with reliable fossil constraints, the incompatibility between paleontological and molecular estimates of rodent divergence times can be eliminated using currently available tools and genetic markers. Similar conflicts between molecular and paleontological evidence bedevil attempts to establish the origination times of other placental groups. The example of the present study suggests that more reliable fossil calibration points may represent the key to resolving these controversies. PMID:23071573

  12. Public health implications of changing rodent importation patterns— United States, 1999–2013

    PubMed Central

    Lankau, Emily W.; Sinclair, Julie R.; Schroeder, Betsy A.; Galland, G. Gale; Marano, Nina

    2015-01-01

    Summary The United States imports a large volume of live wild and domestic animal species; these animals pose a demonstrated risk for introduction of zoonotic diseases. Rodents are imported for multiple purposes, including scientific research, zoo exhibits, and the pet trade. Current U.S. public health regulatory restrictions specific to rodent importation pertain only to those of African origin. To understand the impacts of these regulations and the potential public health risks of international rodent trade to the United States, we evaluated live rodent import records during 1999 –2013 by shipment volume and geographic origin, source (e.g., wild -caught versus captive-or commercially bred), intended purpose, and rodent taxonomy. Live rodent imports increased from 2,737 animals during 1999 to 173,761 animals during 2013. Increases in both the number and size of shipments contributed to this trend. The proportion of wild-captured imports declined from 75% during 1999 to <1% during 2013. Nearly all shipments during these years were imported for commercial purposes. Imports from Europe and other countries in North America experienced notable increases in volume. Gerbils and hamsters arriving from Europe and chinchillas, guinea pigs, and hamsters arriving from other countries in North America were predominant taxa underlying this trend . After 2003, African-origin imports became sporadic events under the federal permit process. These patterns suggest development of large -scale captive rodent breeding markets abroad for commercial sale in the United States. While the shift from wild-captured imports alleviates many conservation concerns and risks for novel disease emergence, such consolidated sourcing might elevate exposure risks for zoonotic diseases associated with high-density rodent breeding(e.g. , lymphocytic choriomeningitis or salmonellosis). A responsive border health system must periodically re-evaluate importation regulations in conjunction with key

  13. Relationships between Rodent White Adipose Fat Pads and Human White Adipose Fat Depots

    PubMed Central

    Chusyd, Daniella E.; Wang, Donghai; Huffman, Derek M.; Nagy, Tim R.

    2016-01-01

    The objective of this review was to compare and contrast the physiological and metabolic profiles of rodent white adipose fat pads with white adipose fat depots in humans. Human fat distribution and its metabolic consequences have received extensive attention, but much of what has been tested in translational research has relied heavily on rodents. Unfortunately, the validity of using rodent fat pads as a model of human adiposity has received less attention. There is a surprisingly lack of studies demonstrating an analogous relationship between rodent and human adiposity on obesity-related comorbidities. Therefore, we aimed to compare known similarities and disparities in terms of white adipose tissue (WAT) development and distribution, sexual dimorphism, weight loss, adipokine secretion, and aging. While the literature supports the notion that many similarities exist between rodents and humans, notable differences emerge related to fat deposition and function of WAT. Thus, further research is warranted to more carefully define the strengths and limitations of rodent WAT as a model for humans, with a particular emphasis on comparable fat depots, such as mesenteric fat. PMID:27148535

  14. Antitumor Efficacy Testing in Rodents

    PubMed Central

    2008-01-01

    The preclinical research and human clinical trials necessary for developing anticancer therapeutics are costly. One contributor to these costs is preclinical rodent efficacy studies, which, in addition to the costs associated with conducting them, often guide the selection of agents for clinical development. If inappropriate or inaccurate recommendations are made on the basis of these preclinical studies, then additional costs are incurred. In this commentary, I discuss the issues associated with preclinical rodent efficacy studies. These include the identification of proper preclinical efficacy models, the selection of appropriate experimental endpoints, and the correct statistical evaluation of the resulting data. I also describe important experimental design considerations, such as selecting the drug vehicle, optimizing the therapeutic treatment plan, properly powering the experiment by defining appropriate numbers of replicates in each treatment arm, and proper randomization. Improved preclinical selection criteria can aid in reducing unnecessary human studies, thus reducing the overall costs of anticancer drug development. PMID:18957675

  15. The need to implement the landscape of fear within rodent pest management strategies

    PubMed Central

    Belmain, Steven R; Singleton, Grant R; Groot Koerkamp, Peter WG; Meerburg, Bastiaan G

    2017-01-01

    Abstract Current reactive pest management methods have serious drawbacks such as the heavy reliance on chemicals, emerging genetic rodenticide resistance and high secondary exposure risks. Rodent control needs to be based on pest species ecology and ethology to facilitate the development of ecologically based rodent management (EBRM). An important aspect of EBRM is a strong understanding of rodent pest species ecology, behaviour and spatiotemporal factors. Gaining insight into the behaviour of pest species is a key aspect of EBRM. The landscape of fear (LOF) is a mapping of the spatial variation in the foraging cost arising from the risk of predation, and reflects the levels of fear a prey species perceives at different locations within its home range. In practice, the LOF maps habitat use as a result of perceived fear, which shows where bait or traps are most likely to be encountered and used by rodents. Several studies have linked perceived predation risk of foraging animals with quitting‐harvest rates or giving‐up densities (GUDs). GUDs have been used to reflect foraging behaviour strategies of predator avoidance, but to our knowledge very few papers have directly used GUDs in relation to pest management strategies. An opportunity for rodent control strategies lies in the integration of the LOF of rodents in EBRM methodologies. Rodent management could be more efficient and effective by concentrating on those areas where rodents perceive the least levels of predation risk. © 2017 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. PMID:28556521

  16. Infection levels of intestinal helminths in two commensal rodent species from rural households in Yucatan, Mexico.

    PubMed

    Panti-May, J A; Hernández-Betancourt, S F; Rodríguez-Vivas, R I; Robles, M R

    2015-01-01

    The aim of the present study was to calculate the prevalence and intensity of intestinal helminths in the house mouse (Mus musculus) and the black rat (Rattus rattus) trapped in rural households of Yucatan, Mexico. Sampling was conducted during the rainy season from October to December 2011 and the dry season from January to March 2012. A total of 154 M. musculus and 46 R. rattus were examined, with 84.2% of M. musculus being infected with helminths compared with a significantly lower prevalence of 52.2% in R. rattus (P< 0.01). Adult M. musculus were more likely to be infected with helminths (89%) than subadults (63%) (P< 0.01). Four helminth species were identified: Taenia taeniaeformis larvae, Nippostrongylus brasiliensis, Syphacia muris and Trichuris muris. Nippostrongylus brasiliensis was present more frequently in M. musculus than in R. rattus (P< 0.01) and in adult mice compared to subadults (P< 0.01). Trichuris muris was present only in adult mice. This is the first report of N. brasiliensis, S. muris and T. muris in Yucatan, Mexico, as well as the first to report the presence of N. brasiliensis in M. musculus from Mexico. The helminth fauna of commensal rodents present in households appears to constitute a low potential health risk to local inhabitants; however, it would be advisable to conduct further studies to better understand the public health risk posed by these rodent intestinal helminths.

  17. Helminth Infections of Rodents and Their Zoonotic Importance in Boyer-Ahmad District, Southwestern Iran

    PubMed Central

    RANJBAR, Mohammad Javad; SARKARI, Bahador; MOWLAVI, Gholam Reza; SEIFOLLAHI, Zeinab; MOSHFE, Abdolali; ABDOLAHI KHABISI, Samaneh; MOBEDI, Iraj

    2017-01-01

    Background: Rodents are considered as reservoirs of various zoonotic diseases including helminthic infections. The current study aimed to evaluate the prevalence of helminth infections in rodents, in Boyer-Ahmad district, Southwestern Iran. Methods: Overall, 52 rodents were captured from various areas of the district by Sherman live traps. The animals were then euthanized and dissected. During necropsy, each organ was examined macroscopically for presence of any cyst or visible parasite. The gastrointestinal tract was removed and their contents were evaluated for larva or adult worms. Trichinella larvae in the rodents’ muscles were investigated by both digestion and pathological methods. Results: Twenty-eight (53.8%) of the trapped rodents were male. The rodents were including 25 (48.1%) Meriones persicus, 1(1.9%) Calomyscus bailwardi, 1 (1.9%) Arvicola terresterris, 7 (13.5%) Rattus rattus, 8 (15.4%) R. norvegicus, and 10 (19.2%) Apodemus sylvaticus. Of them, 38 (73.0%) were infected with at least one helminth. Collected rodents were infected with Hymenolepis diminuta (50%), Hymenolepis nana fraterna (28.8%), Skrjabinotaenia sp. (15.4%), Anoplocephalidae sp. (15.4%), Cysticercus fasciolaris (5.8%), Trichuris muris (36.5%), Aspiculuris tetraptera (15.4%), Syphacia sp. (5.7%), Rictularia sp. (15.4%), Trichostrongylus sp. (3.8%), and Gongylonema sp. (3.8%). M. persicus was the most (84%) infected rodent, yet the differences between rodent genus and helminth infectivity were not statistically significant (P>0.05). Conclusion: The rodents in Boyer-Ahmad district are infected with different helminths infections that some of them are recognized as threat to human health. PMID:29317882

  18. The water economy of South American desert rodents: from integrative to molecular physiological ecology.

    PubMed

    Bozinovic, Francisco; Gallardo, Pedro

    2006-01-01

    Rodents from arid and semi-arid habitats live under conditions where the spatial and temporal availability of free water is limited, or scarce, thus forcing these rodents to deal with the problem of water conservation. The response of rodents to unproductive desert environments and water deficits has been intensively investigated in many deserts of the world. However, current understanding of the cellular, systemic and organismal physiology of water economy relies heavily on short-term, laboratory-oriented experiments, which usually focus on responses at isolated levels of biological organization. In addition, studies in small South American mammals are scarce. Indeed xeric habitats have existed in South America for a long time and it is intriguing why present day South American desert rodents do not show the wide array of adaptive traits to desert life observed for rodents on other continents. Several authors have pointed out that South American desert rodents lack physiological and energetic specialization for energy and water conservation, hypothesizing that their success is based more on behavioral and ecological strategies. We review phenotypic flexibility and physiological diversity in water flux rate, urine osmolality, and expression of water channels in South American desert-dwelling rodents. As far as we know, this is the first review of integrative studies at cellular, systemic and organismal levels. Our main conclusion is that South American desert rodents possess structural as well as physiological systems for water conservation, which are as remarkable as those found in "classical" rodents inhabiting other desert areas of the world.

  19. Optimizing Cardiovascular Benefits of Exercise: A Review of Rodent Models

    PubMed Central

    Davis, Brittany; Moriguchi, Takeshi; Sumpio, Bauer

    2013-01-01

    Although research unanimously maintains that exercise can ward off cardiovascular disease (CVD), the optimal type, duration, intensity, and combination of forms are yet not clear. In our review of existing rodent-based studies on exercise and cardiovascular health, we attempt to find the optimal forms, intensities, and durations of exercise. Using Scopus and Medline, a literature review of English language comparative journal studies of cardiovascular benefits and exercise was performed. This review examines the existing literature on rodent models of aerobic, anaerobic, and power exercise and compares the benefits of various training forms, intensities, and durations. The rodent studies reviewed in this article correlate with reports on human subjects that suggest regular aerobic exercise can improve cardiac and vascular structure and function, as well as lipid profiles, and reduce the risk of CVD. Findings demonstrate an abundance of rodent-based aerobic studies, but a lack of anaerobic and power forms of exercise, as well as comparisons of these three components of exercise. Thus, further studies must be conducted to determine a truly optimal regimen for cardiovascular health. PMID:24436579

  20. Structured networks support sparse traveling waves in rodent somatosensory cortex.

    PubMed

    Moldakarimov, Samat; Bazhenov, Maxim; Feldman, Daniel E; Sejnowski, Terrence J

    2018-05-15

    Neurons responding to different whiskers are spatially intermixed in the superficial layer 2/3 (L2/3) of the rodent barrel cortex, where a single whisker deflection activates a sparse, distributed neuronal population that spans multiple cortical columns. How the superficial layer of the rodent barrel cortex is organized to support such distributed sensory representations is not clear. In a computer model, we tested the hypothesis that sensory representations in L2/3 of the rodent barrel cortex are formed by activity propagation horizontally within L2/3 from a site of initial activation. The model explained the observed properties of L2/3 neurons, including the low average response probability in the majority of responding L2/3 neurons, and the existence of a small subset of reliably responding L2/3 neurons. Sparsely propagating traveling waves similar to those observed in L2/3 of the rodent barrel cortex occurred in the model only when a subnetwork of strongly connected neurons was immersed in a much larger network of weakly connected neurons.

  1. A house officer-sponsored quality improvement initiative: leadership lessons and liabilities.

    PubMed

    Weingart, S N

    1998-07-01

    House officers play an important role in the care of hospitalized patients, yet they are infrequent participants in quality improvement (QI) activities. A grassroots QI initiative among medical house officers was implemented at Beth Israel Deaconess Medical Center's East Campus in Boston from 1995 through 1997. A group of house officer volunteers completed five of nine projects, including a survey that demonstrated frequent failures of cardiac monitor-defibrillators in the emergency room. Reaching out to key administrators produced several quick fixes. Developing effective, ongoing partnerships with clinical departments and QI professionals proved more problematic. Residency training programs that provide experience in QI give house officers a potentially valuable skill and an additional means to improve the quality of patient care. Yet many obstacles work against house officers' participation in QI initiatives, including long hours and the daily demands of patient care, rotating monthly assignments, and clinical leaders' assumption that they have little interest in QI. The organizers of the officer problem-solving group over-estimated the hospital resources at their disposal and failed to build mechanisms to ensure the initiative's continuation into its second year, when their own interest waned and no new group of leaders emerged to take their place. House officers represent an underused resource for QI. They are skilled at identifying problems but have difficulty executing sustained and complex QI initiatives. Peer leadership is a potent means to mobilize resident-physician participation but may require faculty or staff involvement and support to guarantee its continuity.

  2. Tick parasites of rodents in Romania: host preferences, community structure and geographical distribution.

    PubMed

    Mihalca, Andrei D; Dumitrache, Mirabela O; Sándor, Attila D; Magdaş, Cristian; Oltean, Miruna; Györke, Adriana; Matei, Ioana A; Ionică, Angela; D'Amico, Gianluca; Cozma, Vasile; Gherman, Călin M

    2012-11-21

    Ticks are among the most important vectors of zoonotic diseases in temperate regions of Europe, with widespread distribution and high densities, posing an important medical risk. Most ticks feed on a variety of progressively larger hosts, with a large number of small mammal species typically harbouring primarily the immature stages. However, there are certain Ixodidae that characteristically attack micromammals also during their adult stage. Rodents are widespread hosts of ticks, important vectors and competent reservoirs of tick-borne pathogens. Micromammal-tick associations have been poorly studied in Romania, and our manuscript shows the results of a large scale study on tick infestation epidemiology in rodents from Romania. Rodents were caught using snap-traps in a variety of habitats in Romania, between May 2010 and November 2011. Ticks were individually collected from these rodents and identified to species and development stage. Frequency, mean intensity, prevalence and its 95% confidence intervals were calculated using the EpiInfo 2000 software. A p value of <0.05 was considered statistically significant. We examined 423 rodents (12 species) collected from six counties in Romania for the presence of ticks. Each collected tick was identified to species level and the following epidemiological parameters were calculated: prevalence, mean intensity and mean abundance. The total number of ticks collected from rodents was 483, with eight species identified: Ixodes ricinus, I. redikorzevi, I. apronophorus, I. trianguliceps, I. laguri, Dermacentor marginatus, Rhipicephalus sanguineus and Haemaphysalis sulcata. The overall prevalence of tick infestation was 29.55%, with a mean intensity of 3.86 and a mean abundance of 1.14. Only two polyspecific infestations were found: I. ricinus + I. redikorzevi and I. ricinus + D. marginatus. Our study showed a relatively high diversity of ticks parasitizing rodents in Romania. The most common tick in rodents was I. ricinus

  3. Tick parasites of rodents in Romania: host preferences, community structure and geographical distribution

    PubMed Central

    2012-01-01

    Background Ticks are among the most important vectors of zoonotic diseases in temperate regions of Europe, with widespread distribution and high densities, posing an important medical risk. Most ticks feed on a variety of progressively larger hosts, with a large number of small mammal species typically harbouring primarily the immature stages. However, there are certain Ixodidae that characteristically attack micromammals also during their adult stage. Rodents are widespread hosts of ticks, important vectors and competent reservoirs of tick-borne pathogens. Micromammal-tick associations have been poorly studied in Romania, and our manuscript shows the results of a large scale study on tick infestation epidemiology in rodents from Romania. Methods Rodents were caught using snap-traps in a variety of habitats in Romania, between May 2010 and November 2011. Ticks were individually collected from these rodents and identified to species and development stage. Frequency, mean intensity, prevalence and its 95% confidence intervals were calculated using the EpiInfo 2000 software. A p value of <0.05 was considered statistically significant. Results We examined 423 rodents (12 species) collected from six counties in Romania for the presence of ticks. Each collected tick was identified to species level and the following epidemiological parameters were calculated: prevalence, mean intensity and mean abundance. The total number of ticks collected from rodents was 483, with eight species identified: Ixodes ricinus, I. redikorzevi, I. apronophorus, I. trianguliceps, I. laguri, Dermacentor marginatus, Rhipicephalus sanguineus and Haemaphysalis sulcata. The overall prevalence of tick infestation was 29.55%, with a mean intensity of 3.86 and a mean abundance of 1.14. Only two polyspecific infestations were found: I. ricinus + I. redikorzevi and I. ricinus + D. marginatus. Conclusions Our study showed a relatively high diversity of ticks parasitizing rodents in Romania. The most

  4. Stress, social behavior, and resilience: Insights from rodents

    PubMed Central

    Beery, Annaliese K.; Kaufer, Daniela

    2014-01-01

    The neurobiology of stress and the neurobiology of social behavior are deeply intertwined. The social environment interacts with stress on almost every front: social interactions can be potent stressors; they can buffer the response to an external stressor; and social behavior often changes in response to stressful life experience. This review explores mechanistic and behavioral links between stress, anxiety, resilience, and social behavior in rodents, with particular attention to different social contexts. We consider variation between several different rodent species and make connections to research on humans and non-human primates. PMID:25562050

  5. Rodent and flea abundance fail to predict a plague epizootic in black-tailed prairie dogs.

    PubMed

    Brinkerhoff, Robert Jory; Collinge, Sharon K; Ray, Chris; Gage, Ken L

    2010-01-01

    Small rodents are purported to be enzootic hosts of Yersinia pestis and may serve as sources of infection to prairie dogs or other epizootic hosts by direct or flea-mediated transmission. Recent research has shown that small rodent species composition and small rodent flea assemblages are influenced by the presence of prairie dogs, with higher relative abundance of both small rodents and fleas at prairie dog colony sites compared to grasslands without prairie dogs. However, it is unclear if increased rodent or flea abundance predisposes prairie dogs to infection with Y. pestis. We tracked rodent and flea occurrence for 3 years at a number of prairie dog colony sites in Boulder County, Colorado, before, during, and after a local plague epizootic to see if high rodent or flea abundance was associated with plague-affected colonies when compared to colonies that escaped infection. We found no difference in preepizootic rodent abundance or flea prevalence or abundance between plague-positive and plague-negative colonies. Further, we saw no significant before-plague/after-plague change in these metrics at either plague-positive or plague-negative sites. We did, however, find that small rodent species assemblages changed in the year following prairie dog die-offs at plague-affected colonies when compared to unaffected colonies. In light of previous research from this system that has shown that landscape features and proximity to recently plagued colonies are significant predictors of plague occurrence in prairie dogs, we suggest that landscape context is more important to local plague occurrence than are characteristics of rodent or flea species assemblages.

  6. Leptospirosis Survey of Rodents and Domestic Animals in Ethiopia

    DTIC Science & Technology

    1976-08-01

    bovin --. leptospirosis . Amer. J. Vet. Res. 15, 434. Sulzer, C. R., Harvey, T. W., and Galton, M. M, (1968) Comparison of diagnostic technics for the...U.S. DEPARTMENT OF COMMERCE National Technical Inforuation Service AD-A033 991 LEPTOSPIROSIS SURVEY OF RODENTS AND DOMESTIC ANIMALS IN ETHIOPIA NAVAL...34) Domestic animals. Ethiopia. Leptospirosis.Rodents. ien suoy wasa c’r ’ ubtosryds,’C and domestic animals for leptospirosis in 5 sites in western and

  7. Comparison of food hoarding of two sympatric rodent species under interspecific competition.

    PubMed

    Zhang, Yi-Feng; Tong, Lei; Ji, Wei-Hong; Lu, Ji-Qi

    2013-01-01

    Competition can greatly affect the food hoarding strategies of rodents and the fate of seeds hoarded. In order to understand the influence of interspecific competition on food caching behavior of sympatric rodents, we investigated food hoarding patterns of two sympatric rodent species, buff-breasted rat (Rattus flavipectus) and Chinese white-bellied rat (Niviventor confucianus), and compared their responses and adjustment in hoarding behavior under interspecific competition. The results showed that: (1) the buff-breasted rat larder hoarded seeds only, while Chinese white-bellied rat hoarded seeds in both larder and scatter forms; (2) two species of rodents both larder hoarded more seeds when competitors were present; and (3) the Chinese white-bellied rats adjusted their seed hoarding from scatter to larder when competitors were introduced, which reduced the seed availability. Therefore, we concluded that rodents would adjust their food hoarding strategy when interspecific competitors were present, and this may produce a different effect on the fate of seeds and the recruitment of plants. This article is part of a Special Issue entitled: insert SI title. Copyright © 2012. Published by Elsevier B.V.

  8. The need to implement the landscape of fear within rodent pest management strategies.

    PubMed

    Krijger, Inge M; Belmain, Steven R; Singleton, Grant R; Groot Koerkamp, Peter Wg; Meerburg, Bastiaan G

    2017-12-01

    Current reactive pest management methods have serious drawbacks such as the heavy reliance on chemicals, emerging genetic rodenticide resistance and high secondary exposure risks. Rodent control needs to be based on pest species ecology and ethology to facilitate the development of ecologically based rodent management (EBRM). An important aspect of EBRM is a strong understanding of rodent pest species ecology, behaviour and spatiotemporal factors. Gaining insight into the behaviour of pest species is a key aspect of EBRM. The landscape of fear (LOF) is a mapping of the spatial variation in the foraging cost arising from the risk of predation, and reflects the levels of fear a prey species perceives at different locations within its home range. In practice, the LOF maps habitat use as a result of perceived fear, which shows where bait or traps are most likely to be encountered and used by rodents. Several studies have linked perceived predation risk of foraging animals with quitting-harvest rates or giving-up densities (GUDs). GUDs have been used to reflect foraging behaviour strategies of predator avoidance, but to our knowledge very few papers have directly used GUDs in relation to pest management strategies. An opportunity for rodent control strategies lies in the integration of the LOF of rodents in EBRM methodologies. Rodent management could be more efficient and effective by concentrating on those areas where rodents perceive the least levels of predation risk. © 2017 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. © 2017 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

  9. Trypanosoma cruzi load in synanthropic rodents from rural areas in Chile.

    PubMed

    Yefi-Quinteros, Esteban; Muñoz-San Martín, Catalina; Bacigalupo, Antonella; Correa, Juana P; Cattan, Pedro E

    2018-03-12

    Trypanosoma cruzi is the agent of Chagas disease, a major public health problem in Latin America. Many wild and domestic animals are naturally infected with T. cruzi; rodents are one of the groups which have been consistently detected infected in different countries. The aim of this work was to characterize blood T. cruzi load in naturally infected rodents from a Chagas disease endemic region in Chile. Baited traps were set in domestic and peridomestic areas of rural dwellings. The rodents were anesthetized and blood sampled; DNA was extracted and the parasite load was quantified by T. cruzi satellite DNA real-time PCR assays. Seventy-one rodents of four species, Rattus rattus, Mus musculus, Phyllotis darwini and Octodon degus, were captured; R. rattus was the most abundant species. Fifty-nine samples (83.1%) were T. cruzi-positive and the median value of the parasite load was 2.99 parasite equivalents (par-eq)/ml. The comparison of frequency of infection or parasite load by species showed no differences. However, one R. rattus presented very elevated parasitemia (1644 par-eq/ml). The overall levels of parasitemia were similar to those found in humans in Chile. The high infection levels in exotic and endemic rodents very near to rural settlements increases their relevance as T. cruzi hosts.

  10. Zoonotic pathogens in Atlantic Forest wild rodents in Brazil: Bartonella and Coxiella infections.

    PubMed

    Rozental, Tatiana; Ferreira, Michelle Santos; Guterres, Alexandro; Mares-Guia, Maria Angélica; Teixeira, Bernardo R; Gonçalves, Jonathan; Bonvicino, Cibele Rodrigues; D'Andrea, Paulo Sergio; de Lemos, Elba Regina Sampaio

    2017-04-01

    Zoonotic pathogens comprise a significant and increasing fraction of all emerging and re-emerging infectious diseases that plague humans. Identifying host species is one of the keys to controlling emerging infectious diseases. From March 2007 until April 2012, we collected a total of 131 wild rodents in eight municipalities of Rio de Janeiro, Brazil. We investigated these rodents for infection with Coxiella burnetii, Bartonella spp. and Rickettsia spp. In total, 22.1% (29/131) of the rodents were infected by at least one pathogen; co-infection was detected in 1.5% (2/131) of rodents. Coxiella burnetii was detected in 4.6% (6/131) of the wild animals, 17.6% of the rodents harbored Bartonella spp. No cases of Rickettsia were identified. Bartonella doshiae and Bartonella vinsonii were the species found on the wild mammals. This report is the first to note C. burnetii, B. doshiae and B. vinsonii natural infections in Atlantic Forest wild rodents in Brazil. Our work highlights the potential risk of transmission to humans, since most of the infected specimens belong to generalist species that live near human dwellings. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Relationship of Hospital Staff Coverage and Delivery Room Resuscitation Practices to Birth Asphyxia.

    PubMed

    Tu, Joanna H; Profit, Jochen; Melsop, Kathryn; Brown, Taylor; Davis, Alexis; Main, Elliot; Lee, Henry C

    2017-02-01

    Objective  The objective of this study was to assess utilization of specialist coverage and checklists in perinatal settings and to examine utilization by birth asphyxia rates. Design  This is a survey study of California maternity hospitals concerning checklist use to prepare for delivery room resuscitation and 24-hour in-house specialist coverage (pediatrician/neonatologist, obstetrician, and obstetric anesthesiologist) and results linked to hospital birth asphyxia rates (preterm and low weight births were excluded). Results  Of 253 maternity hospitals, 138 responded (55%); 59 (43%) indicated checklist use, and in-house specialist coverage ranged from 38% (pediatrician/neonatologist) to 54% (anesthesiology). In-house coverage was more common in urban versus rural hospitals for all specialties ( p  < 0.0001), but checklist use was not significantly different ( p  = 0.88). Higher birth volume hospitals had more specialist coverage ( p  < 0.0001), whereas checklist use did not differ ( p  = 0.3). In-house obstetric coverage was associated with lower asphyxia rates (odds ratio: 0.34; 95% confidence interval [CI]: 0.20, 0.58) in a regression model accounting for other providers. Checklist use was not associated with birth asphyxia (odds ratio: 1.12; 95% CI: 0.75, 1.68). Conclusion  Higher birth volume and urban hospitals demonstrated greater in-house specialist coverage, but checklist use was similar across all hospitals. Current data suggest that in-house obstetric coverage has greater impact on asphyxia than other specialist coverage or checklist use. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  12. Room Acoustics

    NASA Astrophysics Data System (ADS)

    Kuttruff, Heinrich; Mommertz, Eckard

    The traditional task of room acoustics is to create or formulate conditions which ensure the best possible propagation of sound in a room from a sound source to a listener. Thus, objects of room acoustics are in particular assembly halls of all kinds, such as auditoria and lecture halls, conference rooms, theaters, concert halls or churches. Already at this point, it has to be pointed out that these conditions essentially depend on the question if speech or music should be transmitted; in the first case, the criterion for transmission quality is good speech intelligibility, in the other case, however, the success of room-acoustical efforts depends on other factors that cannot be quantified that easily, not least it also depends on the hearing habits of the listeners. In any case, absolutely "good acoustics" of a room do not exist.

  13. Wash room, bunkhouse, first floor interior. This room is a ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Wash room, bunkhouse, first floor interior. This room is a screened porch with the original sinks extant. Light and ventilation was borrowed from the wash room into the toilets and bathing rooms. - Sespe Ranch, Bunkhouse, 2896 Telegraph Road, Fillmore, Ventura County, CA

  14. Methods Used to Evaluate Pain Behaviors in Rodents

    PubMed Central

    Deuis, Jennifer R.; Dvorakova, Lucie S.; Vetter, Irina

    2017-01-01

    Rodents are commonly used to study the pathophysiological mechanisms of pain as studies in humans may be difficult to perform and ethically limited. As pain cannot be directly measured in rodents, many methods that quantify “pain-like” behaviors or nociception have been developed. These behavioral methods can be divided into stimulus-evoked or non-stimulus evoked (spontaneous) nociception, based on whether or not application of an external stimulus is used to elicit a withdrawal response. Stimulus-evoked methods, which include manual and electronic von Frey, Randall-Selitto and the Hargreaves test, were the first to be developed and continue to be in widespread use. However, concerns over the clinical translatability of stimulus-evoked nociception in recent years has led to the development and increasing implementation of non-stimulus evoked methods, such as grimace scales, burrowing, weight bearing and gait analysis. This review article provides an overview, as well as discussion of the advantages and disadvantages of the most commonly used behavioral methods of stimulus-evoked and non-stimulus-evoked nociception used in rodents. PMID:28932184

  15. The valproic acid-induced rodent model of autism.

    PubMed

    Nicolini, Chiara; Fahnestock, Margaret

    2018-01-01

    Autism is a lifelong neurodevelopmental disorder characterized by impairments in social communication and interaction and by repetitive patterns of behavior, interests and activities. While autism has a strong genetic component, environmental factors including toxins, pesticides, infection and drugs are known to confer autism susceptibility, likely by inducing epigenetic changes. In particular, exposure to valproic acid (VPA) during pregnancy has been demonstrated to increase the risk of autism in children. Furthermore, rodents prenatally exposed to this drug display behavioral phenotypes characteristics of the human condition. Indeed, in utero exposure of rodents to VPA represents a robust model of autism exhibiting face, construct and predictive validity. This model might better represent the many cases of idiopathic autism which are of environmental/epigenetic origins than do transgenic models carrying mutations in single autism-associated genes. The VPA model provides a valuable tool to investigate the neurobiology underlying autistic behavior and to screen for novel therapeutics. Here we review the VPA-induced rodent model of autism, highlighting its importance and reliability as an environmentally-induced animal model of autism. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Applying Bim to Built Heritage with Complex Shapes: the Ice House of Filarete's Ospedale Maggiore in Milan, Italy

    NASA Astrophysics Data System (ADS)

    Oreni, D.; Karimi, G.; Barazzetti, L.

    2017-08-01

    This paper presents the development of a BIM model for a stratified historic structure characterized by a complex geometry: Filarete's Ospedale Maggiore ice house, one of the few remaining historic ice houses in Milan (Fig. 1). Filarete, a well-known Renaissance architect and theorist, planned the hospital in the 15th century, but the ice house was built two centuries later with a double-storey irregular octagonal brick structure, half under and half above ground, that enclosed another circular structure called the ice room. The purpose of the double-walled structure was to store ice in the middle and store and preserve perishable food and medicine at the outer side of the ice room. During World War II, major portions of the hospital and the above-ground section of the ice house was bombed and heavily damaged. Later, in 1962, the hospital was restored and rehabilitated into a university, with the plan to conceal the ice house's remaining structure in the courtyard, which ultimately was excavated and incorporated into a new library for the university. A team of engineers, architects, and students from Politecnico di Milano and Carleton University conducted two heritage recording surveys in 2015 and 2016 to fully document the existing condition of the ice house, resulting in an inclusive laser scanner and photogrammetric point cloud dataset. The point cloud data was consolidated and imported into two leading parametric modelling software, Autodesk Revitand Graphisoft ArchiCAD©, with the goal to develop two BIMs in parallel in order to study and compare the software BIM workflow, parametric capabilities, attributes to capture the complex geometry with high accuracy, and the duration for parametric modelling. The comparison study of the two software revealed their workflow limitations, leading to integration of the BIM generative process with other pure modelling software such as Rhinoceros©. The integrative BIM process led to the production of a comprehensive BIM

  17. Thermal evaluation for exposed stone house with quantitative and qualitative approach in mountainous area, Wonosobo, Indonesia

    NASA Astrophysics Data System (ADS)

    Hermawan, Hermawan; Prianto, Eddy

    2017-12-01

    A building can be considered as having a good thermal performance if it can make the occupant comfortable. Thermal comfort can be seen from the occupant's respond toward the architectural elements and the environment, such as lighting, the room crowding, air temperature, humidity, oxygen level, and occupant's behaviours. The objective of this research is to analyse the thermal performance of four different orientation houses in mountainous area. The research was conducted on the four expose stone houses with four different orientations in the slope of Sindoro Mountain which has relative cool temperature, about 26°C. The measurement of the elements above was done quantitatively and qualitatively for 24 hours. The results are as follows. First, the most comfortable house is west-orientation house. Second, based on the quantitative and qualitative observation, there is no significant difference (±5 %). Third, the occupant's behaviours (caring and genen) also become factors influencing occupant's comfort.

  18. Evaluation of cage micro-environment of mice housed on various types of bedding materials

    USGS Publications Warehouse

    Smith, E.; Stockwell, J.D.; Schweitzer, I.; Langley, S.H.; Smith, A.L.

    2004-01-01

    A variety of environmental factors can affect the outcomes of studies using laboratory rodents. One such factor is bedding. Several new bedding materials and processing methods have been introduced to the market in recent years, but there are few reports of their performance. In the studies reported here, we have assessed the cage micro-environment (in-cage ammonia levels, temperature, and humidity) of mice housed on various kinds of bedding and their combinations. We also compared results for bedding supplied as Nestpaks versus loose bedding. We studied C57BL/6J mice (commonly used) and NOD/LtJ mice (heavy soilers) that were maintained, except in one study, in static duplex cages. In general, we observed little effect of bedding type on in-cage temperature or humidity; however, there was considerable variation in ammonia concentrations. The lowest ammonia concentrations occurred in cages housing mice on hardwood bedding or a mixture of corncob and alpha cellulose. In one experiment comparing the micro-environments of NOD/LtJ male mice housed on woodpulp fiber bedding in static versus ventilated caging, we showed a statistically significant decrease in ammonia concentrations in ventilated cages. Therefore, our data show that bedding type affects the micro-environment in static cages and that effects may differ for ventilated cages, which are being used in vivaria with increasing frequency.

  19. Survey of intestinal helminths collected from pet rodents in México.

    PubMed

    Panti-May, Jesús Alonso; Caraveo-Centeno, Luis; Hernández-Betancourt, Silvia F; Robles, María Del Rosario; Machain-Williams, Carlos

    2017-11-01

    In this survey, intestinal helminths from pet rodents in Mérida, México, were analyzed. A total of 46 mice Mus musculus, 28 hamsters Mesocricetus auratus, 23 rats Rattus norvegicus, and 1 gerbil Meriones unguiculatus were purchased from six pet shops and one black market for wildlife in the city of Mérida. The overall prevalence of helminths in rodents was 61.2% (60/98). Six species of helminths were identified: the zoonotic cestode Rodentolepis nana, and the nematodes Aspiculuris tetraptera, Dentostomella translucida, Syphacia obvelata, Syphacia mesocriceti, and Syphacia muris. Of the 60 infected rodents, 25 (41.7%) harbored 2 or 3 species of helminths. Rodentolepis nana was found in 4.3% of mice and 17.9% of hamsters. This is the first report of infection with S. muris in pet rats. Considering the close physical contact between pet rodents and humans, the presence of R. nana in pets represents a potential risk of transmission, especially to children and immunocompromised individuals.

  20. Wild rodents and their ectoparasites in Baluchistan area, southeast of Iran.

    PubMed

    Nateghpour, M; Akhavan, A A; Hanafi-Bojd, A A; Telmadarraiy, Z; Ayazian Mavi, S; Hosseini-Vasoukolaei, N; Motevalli-Haghi, A; Akbarzadeh, K

    2013-03-01

    During 2008-2009 a total of 67 individuals of rodents, Tetera indica, Meriones hurrianae, Meriones libycus and Gerbillus nanus were trapped in three areas, Bampor, Daman and Qasre Qand from Iranshahr and Nikshahr districts. There is a significant difference between comparative abundance of four species (P<0.05). A total of 1422 ectoparasites collected including 299 mites (21%), 127 fleas (8.9%), 972 lice (68.4%) and 24 ticks (1.7%). Significant findings amongst the ectoparasites is the lice group with three species identified, Laelaps accuninata, Andralaelaps hermophrodita and Paracheylaellaps pyriformis being the first record in the study areas. All four captured genera of rodents are known as main/ potential reservoir hosts of zoonotic cutaneous leishmaniasis. The migration habit of rodents may affect the spatial distribution of parasitic ticks and their transmitted diseases like CCHF, which has been reported in recent years from Sistan and Baluchestan province. Monitoring of rodent populations and their ectoparasites will help to predict the potential of zoonotic arthropod-borne diseases.

  1. Staff corridor (room 206, representing rooms 301, 305, 401, 405, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Staff corridor (room 206, representing rooms 301, 305, 401, 405, 501, and 505), looking south towards the staff corridor vestibule (room 206A, representing rooms 305A, 405A, and 505A). - California State Office Building No. 1, 915 Capitol Mall, Sacramento, Sacramento County, CA

  2. Rodent reservoirs of future zoonotic diseases

    PubMed Central

    Han, Barbara A.; Schmidt, John Paul; Bowden, Sarah E.; Drake, John M.

    2015-01-01

    The increasing frequency of zoonotic disease events underscores a need to develop forecasting tools toward a more preemptive approach to outbreak investigation. We apply machine learning to data describing the traits and zoonotic pathogen diversity of the most speciose group of mammals, the rodents, which also comprise a disproportionate number of zoonotic disease reservoirs. Our models predict reservoir status in this group with over 90% accuracy, identifying species with high probabilities of harboring undiscovered zoonotic pathogens based on trait profiles that may serve as rules of thumb to distinguish reservoirs from nonreservoir species. Key predictors of zoonotic reservoirs include biogeographical properties, such as range size, as well as intrinsic host traits associated with lifetime reproductive output. Predicted hotspots of novel rodent reservoir diversity occur in the Middle East and Central Asia and the Midwestern United States. PMID:26038558

  3. Guide to Commensal Rodent Control

    DTIC Science & Technology

    1991-12-01

    in many detergents also fluoresce. For positive identification, place the suspect material on Urease Siom lhymol Blue test paper, moisten with water...are applied in a thin layer in protected rat and mouse r’unways, baitboxes, or tubes along walls. The powder is picked up by the rodents on their feet

  4. Microbial diversity in European and South American spacecraft assembly clean rooms

    NASA Astrophysics Data System (ADS)

    Moissl-Eichinger, Christine; Stieglmeier, Michaela; Schwendner, Petra

    Spacecraft assembly clean rooms are unique environments for microbes: Due to low nutri-ent levels, desiccated, clean conditions, constant control of humidity and temperature, these environments are quite inhospitable to microbial life and even considered "extreme". Many procedures keep the contamination as low as possible, but these conditions are also highly se-lective for indigenous microbial communities. For space missions under planetary protection requirements, it is crucial to control the contaminating bioburden as much as possible; but for the development of novel cleaning/sterilization methods it is also important to identify and characterize (understand) the present microbial community of spacecraft clean rooms. In prepa-ration for the recently approved ESA ExoMars mission, two European and one South American spacecraft assembly clean rooms were analyzed with respect to their microbial diversity, using standard procedures, new cultivation approaches and molecular methods, that should shed light onto the presence of planetary protection relevant microorganisms. For this study, the Her-schel Space Observatory (launched in May 2009) and its housing clean rooms in Friedrichshafen (Germany), at ESTEC (The Netherlands) and CSG, Kourou (French Guyana) were sampled during assembly, test and launch operations. Although Herschel does not demand planetary protection requirements, all clean rooms were in a fully operating state during sampling. This gave us the opportunity to sample the microbial diversity under strict particulate and molecular contamination-control. Samples were collected from spacecraft and selected clean room surface areas and were subjected to cultivation assays (32 different media), molecular studies (based on 16S rRNA gene sequence analysis) and quantitative PCR. The results from different strategies will be compared and critically discussed, showing the advantages and limits of the selected methodologies. This talk will sum up the lessons

  5. Occurrence and distribution of Giardia species in wild rodents in Germany.

    PubMed

    Helmy, Yosra A; Spierling, Nastasja G; Schmidt, Sabrina; Rosenfeld, Ulrike M; Reil, Daniela; Imholt, Christian; Jacob, Jens; Ulrich, Rainer G; Aebischer, Toni; Klotz, Christian

    2018-03-27

    Giardiasis is an important gastrointestinal parasitic disease in humans and other mammals caused by the protozoan Giardia duodenalis. This species complex is represented by genetically distinct groups (assemblages A-H) with varying zoonotic potential and host preferences. Wild rodents can harbor potentially zoonotic assemblages A and B, and the rodent-specific assemblage G. Other Giardia spp. found in these animals are Giardia muris and Giardia microti. For the latter, only limited information on genetic typing is available. It has been speculated that wild rodents might represent an important reservoir for parasites causing human giardiasis. The aim of this study was to investigate the occurrence and distribution of Giardia spp. and assemblage types in wild rodents from different study sites in Germany. Screening of 577 wild rodents of the genera Apodemus, Microtus and Myodes, sampled at eleven study sites in Germany, revealed a high overall Giardia prevalence. Giardia species determination at the SSU rDNA gene locus revealed that Apodemus mice, depending on species, were predominantly infected with one of two distinct G. muris sequence types. Giardia microti was the predominant parasite species found in voles of the genera Microtus and Myodes. Only a few animals were positive for potentially zoonotic G. duodenalis. Subtyping at the beta-giardin (bg) and glutamine dehydrogenase (gdh) genes strongly supported the existence of different phylogenetic subgroups of G. microti that are preferentially harbored by distinct host species. The present study highlights the preference of G. muris for Apodemus, and G. microti for Microtus and Myodes hosts and argues for a very low prevalence of zoonotic G. duodenalis assemblages in wild rodents in Germany. It also provides evidence that G. muris and G. microti subdivide into several phylogenetically distinguishable subgroups, each of which appears to be preferentially harbored by species of a particular rodent host genus

  6. Domestic cats and dogs create a landscape of fear for pest rodents around rural homesteads.

    PubMed

    Mahlaba, Themb'alilahlwa A M; Monadjem, Ara; McCleery, Robert; Belmain, Steven R

    2017-01-01

    Using domestic predators such as cats to control rodent pest problems around farms and homesteads is common across the world. However, practical scientific evidence on the impact of such biological control in agricultural settings is often lacking. We tested whether the presence of domestic cats and/or dogs in rural homesteads would affect the foraging behaviour of pest rodents. We estimated giving up densities (GUDs) from established feeding patches and estimated relative rodent activity using tracking tiles at 40 homesteads across four agricultural communities. We found that the presence of cats and dogs at the same homestead significantly reduced activity and increased GUDs (i.e. increased perception of foraging cost) of pest rodent species. However, if only cats or dogs alone were present at the homestead there was no observed difference in rodent foraging activity in comparison to homesteads with no cats or dogs. Our results suggest that pest rodent activity can be discouraged through the presence of domestic predators. When different types of predator are present together they likely create a heightened landscape of fear for foraging rodents.

  7. Protozoan Parasites of Rodents and Their Zoonotic Significance in Boyer-Ahmad District, Southwestern Iran

    PubMed Central

    Seifollahi, Zeinab; Motazedian, Mohammad Hossein; Asgari, Qasem; Ranjbar, Mohammad Javad; Abdolahi Khabisi, Samaneh

    2016-01-01

    Backgrounds. Wild rodents are reservoirs of various zoonotic diseases, such as toxoplasmosis, babesiosis, and leishmaniasis. The current study aimed to assess the protozoan infection of rodents in Boyer-Ahmad district, southwestern Iran. Materials and Methods. A total of 52 rodents were collected from different parts of Boyer-Ahmad district, in Kohgiluyeh and Boyer-Ahmad province, using Sherman live traps. Each rodent was anesthetized with ether, according to the ethics of working with animals, and was dissected. Samples were taken from various tissues and stool samples were collected from the contents of the colon and small intestines. Moreover, 2 to 5 mL of blood was taken from each of the rodents and the sera were examined for anti-Leishmania antibodies, by ELISA, or anti-T. gondii antibodies, by modified agglutination test (MAT). DNA was extracted from brain tissue samples of each rodent and PCR was used to identify the DNA of T. gondii. Results. Of the 52 stool samples of rodents studied by parasitological methods, intestinal protozoa infection was seen in 28 cases (53.8%). From 52 rodents, 19 (36.5%) were infected with Trichomonas, 10 (19.2%) with Giardia muris, and 11 (21.2%) with Entamoeba spp. Also, 10 cases (19.2%) were infected with Blastocystis, 3 (5.8%) were infected with Chilomastix, 7 (13.5%) were infected with Endolimax, 1 (1.9%) was infected with Retortamonas, 3 (5.77%) were infected with T. gondii, and 6 (11.54%) were infected with Trypanosoma lewisi. Antibodies to T. gondii were detected in the sera of 5 (9.61%) cases. Results of the molecular study showed T. gondii infection in 3 (5.77%) of the rodents. Findings of this study showed that rodents in Kohgiluyeh and Boyer-Ahmad province, southwestern Iran, are infected with several blood and intestinal parasites; some of them might be potential risks to residents and domestic animals in the region. PMID:26998380

  8. [Dynamic model of seasonal breeding rodent pest population controlled with short-acting sterilant].

    PubMed

    Liu, Han-wu; Jin, Zhen; Zhang, Feng-qin; Li, Qiu-ying

    2013-04-01

    Rodent pests bring great damage to human beings, while rodenticide and sterilant can be used to control the pests. After ingesting sterilant, rodent pests lose their fertility, but in some cases, the sterile individuals may gain their fertility again, produce offspring, and enlarge population size. In this paper, the dynamic models of rodent pest population under lethal control and shortacting contraception control were formulated, and, with the prerequisite of the seasonal breeding of rodent pest population, the models were used to regularly analyze their behaviors and the effects of the contraception rate, lethal rate, control interval, and sterilant valid period on the dynamics of the pest population. The results showed that larger contraception rate and lethal rate and shorter control interval could have better control effect, making the controlled population become smaller and even died out. Short-acting sterilant limited the control effect. At the later period of breeding season, the rodent pest population controlled with short-acting sterilant would have a weak recovery.

  9. Small rodents as paratenic or intermediate hosts of carnivore parasites in Berlin, Germany.

    PubMed

    Krücken, Jürgen; Blümke, Julia; Maaz, Denny; Demeler, Janina; Ramünke, Sabrina; Antolová, Daniela; Schaper, Roland; von Samson-Himmelstjerna, Georg

    2017-01-01

    Rodents are important intermediate and paratenic hosts for carnivore parasites, including the important zoonotic agents Toxoplasma, Echinococcus and Toxocara. Monitoring of such parasites in rodents can be used to detect increasing risks for human and veterinary public health. Rodents were trapped at four sites in Berlin, two near the city center, two at the periphery. PCRs were conducted to detect Coccidia (target ITS-1) and specifically Toxoplasma gondii (repetitive element) in brain and ascarids (ITS-2) in muscle or brain tissue. During necropsies, metacestodes were collected and identified using ITS-2 and 12S rRNA PCRs. An ELISA to detect antibodies against Toxocara canis ES antigens was performed. Within the 257 examined rodents, the most frequently observed parasite was Frenkelia glareoli predominantly found in Myodes glareolus. T. gondii was only detected in 12 rodents and Microtus spp. (although strongly underrepresented) had a significantly increased chance of being positive. Neither Echinococcus nor typical Taenia parasites of dogs and cats were found but Mesocestoides litteratus and Taenia martis metacestodes were identified which can cause severe peritoneal or ocular cysticercosis in dogs, primates and humans. Using PCR, the ascarids T. canis (n = 8), Toxocara cati (4) and Parascaris sp. (1) were detected predominantly in muscles. Seroprevalence of T. canis was 14.2% and ELISA was thus more sensitive than PCR to detect infection with this parasite. Non-parametric multidimensional scaling and cluster analysis revealed that parasite communities could be grouped into an urban and a peri-urban cluster with high frequency of ascarid-positive rodents in urban and high frequency of F. glareoli in peri-urban sites. Prevalence rates of parasites in rodents with potential impact for human or veterinary public health are considerable and the monitoring of transmission cycles of carnivore parasites in intermediate rodent hosts is recommended to estimate the health

  10. Small rodents as paratenic or intermediate hosts of carnivore parasites in Berlin, Germany

    PubMed Central

    Maaz, Denny; Demeler, Janina; Ramünke, Sabrina; Antolová, Daniela; Schaper, Roland; von Samson-Himmelstjerna, Georg

    2017-01-01

    Rodents are important intermediate and paratenic hosts for carnivore parasites, including the important zoonotic agents Toxoplasma, Echinococcus and Toxocara. Monitoring of such parasites in rodents can be used to detect increasing risks for human and veterinary public health. Rodents were trapped at four sites in Berlin, two near the city center, two at the periphery. PCRs were conducted to detect Coccidia (target ITS-1) and specifically Toxoplasma gondii (repetitive element) in brain and ascarids (ITS-2) in muscle or brain tissue. During necropsies, metacestodes were collected and identified using ITS-2 and 12S rRNA PCRs. An ELISA to detect antibodies against Toxocara canis ES antigens was performed. Within the 257 examined rodents, the most frequently observed parasite was Frenkelia glareoli predominantly found in Myodes glareolus. T. gondii was only detected in 12 rodents and Microtus spp. (although strongly underrepresented) had a significantly increased chance of being positive. Neither Echinococcus nor typical Taenia parasites of dogs and cats were found but Mesocestoides litteratus and Taenia martis metacestodes were identified which can cause severe peritoneal or ocular cysticercosis in dogs, primates and humans. Using PCR, the ascarids T. canis (n = 8), Toxocara cati (4) and Parascaris sp. (1) were detected predominantly in muscles. Seroprevalence of T. canis was 14.2% and ELISA was thus more sensitive than PCR to detect infection with this parasite. Non-parametric multidimensional scaling and cluster analysis revealed that parasite communities could be grouped into an urban and a peri-urban cluster with high frequency of ascarid-positive rodents in urban and high frequency of F. glareoli in peri-urban sites. Prevalence rates of parasites in rodents with potential impact for human or veterinary public health are considerable and the monitoring of transmission cycles of carnivore parasites in intermediate rodent hosts is recommended to estimate the health

  11. Response of brown treesnakes to reduction of their rodent prey

    USGS Publications Warehouse

    Gragg, J.E.; Rodda, G.H.; Savidge, J.A.; White, Gary C.; Dean-Bradley, K.; Ellingson, A.R.

    2007-01-01

    Trapping brown treesnakes (Boiga irregularis; BTS) with live-mouse (Mus domesticus) lures is the principal control technique for this invasive species on Guam. Lure-based trapping is also used on other islands as a precaution against undetected arrivals and in response to verified BTS sightings. However, the effectiveness of lure-based trapping on other islands is questionable, as it has yielded no BTS despite other evidence of their presence. Some evidence suggests that high rodent numbers may interfere with BTS control. To test the relationship between rodent abundance and snake trappability, we conducted a controlled, replicated field experiment incorporating a rodenticide treatment during a BTS mark-recapture study. Using open population modeling in Program MARK, we estimated BTS apparent survival and recapture probabilities. Rodent reduction increased BTS recapture probabilities by 52-65% in 2002 and 22-36% in 2003, and it decreased apparent survival by <1% both years. This appears to be the first published instance of manipulating wild prey to influence snake behavior. Rodent reduction may enhance detection and control of BTS with traps on Guam and other islands. It may also amplify the effectiveness of oral toxicants against BTS.

  12. Research of 600C Grade Welding V-N Micro-Alloyed Steel Used on Truck Axle Housing After Thermal Forming

    NASA Astrophysics Data System (ADS)

    Quanli, Wang; Hui, Pan; Qingmei, Liu

    Automobile axle housing is the basic element to install the main reducing gear, differential mechanism, semi-axis, wheel hub and suspension. The main function of automobile axle housing is to support the automobile quality with driven axle, fix the driving wheel relative axial position and bear the driving wheel transmission force during the automobile running. Axle housing steel with the thickness of not less than 12mm is produced by the thermal forming method, which is to heat the plate to 830 degree and hold some time, then thermal forming, and cool to room temperature. The steel plate should maintain the original strength and good ductility and toughness requirements with thermal forming process.

  13. Efficacy, efficiency and safety aspects of hydrogen peroxide vapour and aerosolized hydrogen peroxide room disinfection systems.

    PubMed

    Fu, T Y; Gent, P; Kumar, V

    2012-03-01

    This was a head-to-head comparison of two hydrogen-peroxide-based room decontamination systems. To compare the efficacy, efficiency and safety of hydrogen peroxide vapour (HPV; Clarus R, Bioquell, Andover, U.K.) and aerosolized hydrogen peroxide (aHP; SR2, Sterinis, now supplied as Glosair, Advanced Sterilization Products (ASP), Johnson & Johnson Medical Ltd, Wokingham, U.K.) room disinfection systems. Efficacy was tested using 4- and 6-log Geobacillus stearothermophilus biological indicators (BIs) and in-house prepared test discs containing approximately 10(6) meticillin-resistant Staphylococcus aureus (MRSA), Clostridium difficile and Acinetobacter baumannii. Safety was assessed by detecting leakage of hydrogen peroxide using a hand-held detector. Efficiency was assessed by measuring the level of hydrogen peroxide using a hand-held sensor at three locations inside the room, 2 h after the start of the cycles. HPV generally achieved a 6-log reduction, whereas aHP generally achieved less than a 4-log reduction on the BIs and in-house prepared test discs. Uneven distribution was evident for the aHP system but not the HPV system. Hydrogen peroxide leakage during aHP cycles with the door unsealed, as per the manufacturer's operating manual, exceeded the short-term exposure limit (2 ppm) for more than 2 h. When the door was sealed with tape, as per the HPV system, hydrogen peroxide leakage was <1 ppm for both systems. The mean concentration of hydrogen peroxide in the room 2 h after the cycle started was 1.3 [standard deviation (SD) 0.4] ppm and 2.8 (SD 0.8) ppm for the four HPV and aHP cycles, respectively. None of the readings were <2 ppm for the aHP cycles. The HPV system was safer, faster and more effective for biological inactivation. Crown Copyright © 2012. Published by Elsevier Ltd. All rights reserved.

  14. DEVELOPING A PREDICTIVE SIMULATION MODEL FOR ANTIANDROGEN IMPACTS ON RODENT PROSTATE

    EPA Science Inventory

    Developing a predictive simulation model for antiandrogen impacts on rodent prostate
    HA Barton1, RW Setzer1, LK Potter1,2
    1US EPA, ORD, NHEERL, ETD, PKB, Research Triangle Park, NC and 2Curriculum in Toxicology, UNC, Chapel Hill, NC

    Alterations in rodent prostate wei...

  15. Risk factors for house-entry by malaria vectors in a rural town and satellite villages in The Gambia.

    PubMed

    Kirby, Matthew J; Green, Clare; Milligan, Paul M; Sismanidis, Charalambos; Jasseh, Momadou; Conway, David J; Lindsay, Steven W

    2008-01-07

    In the pre-intervention year of a randomized controlled trial investigating the protective effects of house screening against malaria-transmitting vectors, a multi-factorial risk factor analysis study was used to identify factors that influence mosquito house entry. Mosquitoes were sampled using CDC light traps in 976 houses, each on one night, in Farafenni town and surrounding villages during the malaria-transmission season in The Gambia. Catches from individual houses were both (a) left unadjusted and (b) adjusted relative to the number of mosquitoes caught in four sentinel houses that were operated nightly throughout the period, to allow for night-to-night variation. Houses were characterized by location, architecture, human occupancy and their mosquito control activities, and the number and type of domestic animals within the compound. 106,536 mosquitoes were caught, of which 55% were Anopheles gambiae sensu lato, the major malaria vectors in the region. There were seven fold higher numbers of An. gambiae s.l. in the villages (geometric mean per trap night = 43.7, 95% confidence intervals, CIs = 39.5-48.4) than in Farafenni town (6.3, 5.7-7.2) and significant variation between residential blocks (p < 0.001). A negative binomial multivariate model performed equally well using unadjusted or adjusted trap data. Using the unadjusted data the presence of nuisance mosquitoes was reduced if the house was located in the town (odds ratio, OR = 0.11, 95% CIs = 0.09-0.13), the eaves were closed (OR = 0.71, 0.60-0.85), a horse was tethered near the house (OR = 0.77, 0.73-0.82), and churai, a local incense, was burned in the room at night (OR = 0.56, 0.47-0.66). Mosquito numbers increased per additional person in the house (OR = 1.04, 1.02-1.06) or trapping room (OR = 1.19, 1.13-1.25) and when the walls were made of mud blocks compared with concrete (OR = 1.44, 1.10-1.87). This study demonstrates that the risk of malaria transmission is greatest in rural areas, where large

  16. Prevalence and genetic diversity of Bartonella strains in rodents from northwestern Mexico.

    PubMed

    Rubio, André V; Ávila-Flores, Rafael; Osikowicz, Lynn M; Bai, Ying; Suzán, Gerardo; Kosoy, Michael Y

    2014-12-01

    Bartonella infections were investigated in wild rodents from northwestern Chihuahua, Mexico. A total of 489 rodents belonging to 14 species were surveyed in four areas. Bartonella bacteria were cultured from 50.1% of rodent samples (245/489). Infection rates ranged from 0% to 83.3% per rodent species, with no significant difference between sites except for Cynomys ludovicianus. Phylogenetic analyses of the citrate synthase gene (gltA) of the Bartonella isolates revealed 23 genetic variants (15 novel and 8 previously described), clustering into five phylogroups. Three phylogroups were associated with Bartonella vinsonii subsp. vinsonii, B. vinsonii subsp. arupensis, and B. washoensis, respectively. The other two phylogroups were not genetically related to any known Bartonella species. The genetic variants and phylogenetic groups exhibited a high degree of host specificity, mainly at the genus and family levels. This is the first study that describes the genetic diversity of Bartonella strains in wild rodents from Mexico. Considering that some variants found in this study are associated with Bartonella species that have been reported as zoonotic, more investigations are needed to further understand the ecology of Bartonella species in Mexican wildlife and their implications for human health.

  17. Genetic diversity and evolution of Pneumocystis fungi infecting wild Southeast Asian murid rodents.

    PubMed

    Latinne, Alice; Bezé, François; Delhaes, Laurence; Pottier, Muriel; Gantois, Nausicaa; Nguyen, Julien; Blasdell, Kim; Dei-Cas, Eduardo; Morand, Serge; Chabé, Magali

    2017-11-09

    Pneumocystis organisms are airborne-transmitted fungal parasites that infect the lungs of numerous mammalian species with strong host specificity. In this study, we investigated the genetic diversity and host specificity of Pneumocystis organisms infecting Southeast Asian murid rodents through PCR amplification of two mitochondrial genes and tested the co-phylogeny hypothesis among these fungi and their rodent hosts. Pneumocystis DNA was detected in 215 of 445 wild rodents belonging to 18 Southeast Asian murid species. Three of the Pneumocystis lineages retrieved in our phylogenetic trees correspond to known Pneumocystis species, but some of the remaining lineages may correspond to new undescribed species. Most of these Pneumocystis species infect several rodent species or genera and some sequence types are shared among several host species and genera. These results indicated a weaker host specificity of Pneumocystis species infecting rodents than previously thought. Our co-phylogenetic analyses revealed a complex evolutionary history among Pneumocystis and their rodent hosts. Even if a significant global signal of co-speciation has been detected, co-speciation alone is not sufficient to explain the observed co-phylogenetic pattern and several host switches are inferred. These findings conflict with the traditional view of a prolonged process of co-evolution and co-speciation of Pneumocystis and their hosts.

  18. Effects of Fat and Protein Levels on Foraging Preferences of Tannin in Scatter-Hoarding Rodents

    PubMed Central

    Wang, Bo; Chen, Jin

    2012-01-01

    Both as consumers and dispersers of seeds, scatter-hoarding rodents often play an important role in the reproductive ecology of many plant species. However, the seeds of many plant species contain tannins, which are a diverse group of water-soluble phenolic compounds that have a high affinity for proteins. The amount of tannins in seeds is expected to affect rodent foraging preferences because of their major impact on rodent physiology and survival. However, variable results have been obtained in studies that evaluated the effects of tannin on rodent foraging behavior. Hence, in this study, we aimed to explain these inconsistent results and proposed that a combination of seed traits might be important in rodent foraging behavior, because it is difficult to distinguish between the effects of individual traits on rodent foraging behavior and the interactions among them. By using a novel artificial seed system, we manipulated seed tannin and fat/protein levels to examine directly the univariate effects of each component on the seed preferences of free-ranging forest rats (Apodemus latronum and Apodemus chevrieri) during the behavioral process of scatter hoarding. Our results showed that both tannin and fat/protein had significant effects on rodent foraging behavior. Although only a few interactive effects of tannin and fat/protein were recorded, higher concentrations of both fat and protein could attenuate the exclusion of seeds with higher tannin concentrations by rodents, thus influencing seed fate. Furthermore, aside from the concentrations of tannin, fat, and protein, numerous other traits of plant seeds may also influence rodent foraging behavior. We suggest that by clarifying rodent foraging preferences, a better understanding of the evolution of plant seed traits may be obtained because of their strong potential for selective pressure. PMID:22808217

  19. 4. View of houses from Port Ludlow, houses no. 69 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. View of houses from Port Ludlow, houses no. 69 and 70, facing southwest. House no. 69 in foreground, house no. 70 in background. - Houses Moved from Port Ludlow, Various Addresses (moved from Port Ludlow, WA), Port Gamble, Kitsap County, WA

  20. Use of permethrin eradicated the tropical rat mite (Ornithonyssus bacoti) from a colony of mutagenized and transgenic mice.

    PubMed

    Hill, William A; Randolph, Mildred M; Boyd, Keli L; Mandrell, Timothy D

    2005-09-01

    The tropical rat mite, Ornithonyssus bacoti, was identified in a colony of mutagenized and transgenic mice at a large academic institution. O. bacoti is an obligate, blood-feeding ectoparasite with an extensive host range. Although the source of the infestation was likely feral rodents, none were found in the room housing infested mice. We hypothesize that construction on the floor above the vivarium and compromised ceiling integrity within the animal room provided for vermin entry and subsequent O. bacoti infestation. O. bacoti infestation was eliminated by environmental decontamination with synthetic pyrethroids and weekly application of 7.4% permethrin-impregnated cotton balls to mouse caging for five consecutive weeks. Visual examination of the macroenvironment, microenvironment, and colony for 38 days confirmed the efficacy of treatment. We noted no treatment-related toxicities or effects on colony production.

  1. Options for Dealing With Rodent Infestations

    EPA Pesticide Factsheets

    After removing sources of food and water and shelter, your next options are rodent traps and poisons (rodenticides). Rat or mouse traps may be lethal (snap traps) or live (cage-type), and poison baits must be placed in tamper-resistant bait stations.

  2. Vision in laboratory rodents-Tools to measure it and implications for behavioral research.

    PubMed

    Leinonen, Henri; Tanila, Heikki

    2017-07-29

    Mice and rats are nocturnal mammals and their vision is specialized for detection of motion and contrast in dim light conditions. These species possess a large proportion of UV-sensitive cones in their retinas and the majority of their optic nerve axons target superior colliculus rather than visual cortex. Therefore, it was a widely held belief that laboratory rodents hardly utilize vision during day-time behavior. This dogma is being questioned as accumulating evidence suggests that laboratory rodents are able to perform complex visual functions, such as perceiving subjective contours, and that declined vision may affect their performance in many behavioral tasks. For instance, genetic engineering may have unexpected consequences on vision as mouse models of Alzheimer's and Huntington's diseases have declined visual function. Rodent vision can be tested in numerous ways using operant training or reflex-based behavioral tasks, or alternatively using electrophysiological recordings. In this article, we will first provide a summary of visual system and explain its characteristics unique to rodents. Then, we present well-established techniques to test rodent vision, with an emphasis on pattern vision: visual water test, optomotor reflex test, pattern electroretinography and pattern visual evoked potentials. Finally, we highlight the importance of visual phenotyping in rodents. As the number of genetically engineered rodent models and volume of behavioral testing increase simultaneously, the possibility of visual dysfunctions needs to be addressed. Neglect in this matter potentially leads to crude biases in the field of neuroscience and beyond. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Housing quality, housing instability, and maternal mental health.

    PubMed

    Suglia, Shakira Franco; Duarte, Cristiane S; Sandel, Megan T

    2011-12-01

    Poor housing conditions and residential instability have been associated with distress among women; however, this association could be the result of other social factors related to housing, such as intimate partner violence (IPV) and economic hardship. We examined associations of housing conditions and instability with maternal depression and generalized anxiety disorder (GAD) while accounting for IPV and economic hardship in the Fragile Families and Child Wellbeing Study (N = 2,104). In the third study wave, interviewers rated indoor housing quality, including housing deterioration (e.g., peeling paint and holes in floor) and housing disarray (e.g., dark, crowded, and noisy). Mothers reported whether they had moved more than twice in the past two years, an indicator of housing instability. A screening for depression and GAD was obtained from questions derived from the Composite International Diagnostic Interview-Short Form in the second and third study waves. IPV and economic hardship were assessed through questionnaire. In this sample, 16% of women were classified as having probable depression and 5% as having probable GAD. In adjusted analyses, mothers experiencing housing disarray (odds ratio [OR], 1.3 [95% confidence interval (CI), 1.0, 1.7]) and instability (OR, 1.4 [95% CI, 1.2, 2.3]) were more likely to screen positive for depression. In addition, those experiencing housing instability were more likely to screen positive for GAD (OR 1.9 [95% CI, 1.2, 3.0]) even after adjusting for other social factors. No associations were noted between housing deterioration and maternal mental health. Similar associations were noted when incident cases of probable depression and GAD were examined. Housing instability and disarray, but not deterioration, are associated with screening positive for depression and generalized anxiety among women regardless of other social stressors present in their lives. Housing could potentially present a point of intervention to prevent

  4. Understanding Housing Delays and Relocations Within the Housing First Model.

    PubMed

    Zerger, Suzanne; Pridham, Katherine Francombe; Jeyaratnam, Jeyagobi; Hwang, Stephen W; O'Campo, Patricia; Kohli, Jaipreet; Stergiopoulos, Vicky

    2016-01-01

    This study explores factors contributing to delays and relocations during the implementation of the Housing First model in Toronto, Ontario. While interruptions in housing tenure are expected en route to recovery and housing stability, consumer and service provider views on finding and keeping housing remain largely unknown. In-person interviews and focus groups were conducted with 48 study participants, including 23 case managers or housing workers and 25 consumers. The following three factors contributed to housing delays and transfers: (1) the effectiveness of communication and collaboration among consumers and service providers, (2) consumer-driven preferences and ambivalence, and (3) provider prioritization of consumer choice over immediate housing access. Two strategies--targeted communications and consumer engagement in housing searches--supported the housing process. Several factors affect the timing and stability of housing. Communication between and among providers and consumers, and a shared understanding of consumer choice, can further support choice and recovery.

  5. Too many rodent carcinogens: Mitogenesis increases mutagenesis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ames, B.N.; Gold, L.S.

    1990-08-31

    A clarification of the mechanism of carcinogenesis is developing at a rapid rate. This new understanding undermines many assumptions of current regulatory policy toward rodent carcinogens and necessitates rethinking the utility and meaning of routine animal cancer tests. At a recent watershed meeting on carcinogenesis, much evidence was presented suggesting that mitogenesis plays a dominant role in carcinogenesis. Our own rethinking of mechanism was prompted by our findings that: spontaneous DNA damage caused by endogenous oxidants is remarkably frequent and in chronic testing at the maximum tolerated dose (MTD), more than half of all chemicals tested (both natural and synthetic)more » are carcinogens in rodents, and a high percentage of these carcinogens are not mutagens.« less

  6. Greenhouse Gas Emissions from Three Cage Layer Housing Systems

    PubMed Central

    Fournel, Sébastien; Pelletier, Frédéric; Godbout, Stéphane; Lagacé, Robert; Feddes, John

    2011-01-01

    Simple Summary Greenhouse gas (GHG) emissions were measured from three different cage layer housing systems. A comparative study was conducted to identify the housing system with the least impact on the environment. The results showed that liquid manure from deep-pit housing systems produces greater emissions of carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O) than natural and forced dried manure from belt housing systems. The influencing factors appeared to be the manure removal frequency and the dry matter content of the manure. Abstract Agriculture accounts for 10 to 12% of the World’s total greenhouse gas (GHG) emissions. Manure management alone is responsible for 13% of GHG emissions from the agricultural sector. During the last decade, Québec’s egg production systems have shifted from deep-pit housing systems to manure belt housing systems. The objective of this study was to measure and compare carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O) emissions from three different cage layer housing systems: a deep liquid manure pit and a manure belt with natural or forced air drying. Deep liquid manure pit housing systems consist of “A” frame layer cages located over a closed pit containing the hens’ droppings to which water is added to facilitate removal by pumping. Manure belt techniques imply that manure drops on a belt beneath each row of battery cages where it is either dried naturally or by forced air until it is removed. The experiment was replicated with 360 hens reared into twelve independent bench-scale rooms during eight weeks (19–27 weeks of age). The natural and forced air manure belt systems reduced CO2 (28.2 and 28.7 kg yr−1 hen−1, respectively), CH4 (25.3 and 27.7 g yr−1 hen−1, respectively) and N2O (2.60 and 2.48 g yr−1 hen−1, respectively) emissions by about 21, 16 and 9% in comparison with the deep-pit technique (36.0 kg CO2 yr−1 hen−1, 31.6 g CH4 yr−1 hen−1 and 2.78 g N2O yr−1 hen−1). The

  7. Indoor radiocaesium contamination in residential houses within evacuation areas after the Fukushima nuclear accident

    PubMed Central

    Yoshida-Ohuchi, Hiroko; Kanagami, Takashi; Satoh, Yasushi; Hosoda, Masahiro; Naitoh, Yutaka; Kameyama, Mizuki

    2016-01-01

    Indoor contaminants were investigated from July 2013 to January 2015 within ninety-five residential houses in five evacuation zones, Iitate village, Odaka district, and the towns of Futaba, Okuma, and Tomioka. A dry smear test was applied to the surface of materials and structures in rooms and in the roof-space of houses. We found that 134Cs and 137Cs were the dominant radionuclides in indoor surface contamination, and there was a distance dependence from the Fukushima Daiichi nuclear power plant (FDNPP). For surface contamination in Iitate village (29–49 km from the FDNPP), 24.8% of samples exceeded the detection limit, which is quite a low value, while in Okuma (<3.0 km from the FDNPP), 99.7% of samples exceeded the detection limit and surface contamination levels exceeded 20 Bq/cm2 (the value was corrected to March 2011). In residential houses in Okuma, Futaba, and Tomioka, closer to the FDNPP than those in Odaka district and Iitate village, surface contamination was inversely proportional to the square of the distance between a house and the FDNPP. In the houses closest to the FDNPP, the contribution of surface contamination to the ambient dose equivalent rate was evaluated to be approximately 0.3 μSv/h. PMID:27212076

  8. 2015 Summer Series - Ruth Globus - Flying Through the Ages: Rodent Research for Human Health

    NASA Image and Video Library

    2015-06-16

    Rodents are a model organism to study the short and long term effects of space travel. Building on its space shuttle experience, NASA Ames has developed the Rodent Research Habitat for the International Space Station to implement space biology investigations. Dr. Ruth Globus' seminar takes us into the world of rodent research in space and explains how it can support human health.

  9. Updated Neuronal Scaling Rules for the Brains of Glires (Rodents/Lagomorphs)

    PubMed Central

    Herculano-Houzel, Suzana; Ribeiro, Pedro; Campos, Leandro; Valotta da Silva, Alexandre; Torres, Laila B.; Catania, Kenneth C.; Kaas, Jon H.

    2011-01-01

    Brain size scales as different functions of its number of neurons across mammalian orders such as rodents, primates, and insectivores. In rodents, we have previously shown that, across a sample of 6 species, from mouse to capybara, the cerebral cortex, cerebellum and the remaining brain structures increase in size faster than they gain neurons, with an accompanying decrease in neuronal density in these structures [Herculano-Houzel et al.: Proc Natl Acad Sci USA 2006;103:12138–12143]. Important remaining questions are whether such neuronal scaling rules within an order apply equally to all pertaining species, and whether they extend to closely related taxa. Here, we examine whether 4 other species of Rodentia, as well as the closely related rabbit (Lagomorpha), conform to the scaling rules identified previously for rodents. We report the updated neuronal scaling rules obtained for the average values of each species in a way that is directly comparable to the scaling rules that apply to primates [Gabi et al.: Brain Behav Evol 2010;76:32–44], and examine whether the scaling relationships are affected when phylogenetic relatedness in the dataset is accounted for. We have found that the brains of the spiny rat, squirrel, prairie dog and rabbit conform to the neuronal scaling rules that apply to the previous sample of rodents. The conformity to the previous rules of the new set of species, which includes the rabbit, suggests that the cellular scaling rules we have identified apply to rodents in general, and probably to Glires as a whole (rodents/lagomorphs), with one notable exception: the naked mole-rat brain is apparently an outlier, with only about half of the neurons expected from its brain size in its cerebral cortex and cerebellum. PMID:21985803

  10. Reverberant acoustic energy in auditoria that comprise systems of coupled rooms

    NASA Astrophysics Data System (ADS)

    Summers, Jason E.

    2003-11-01

    A frequency-dependent model for reverberant energy in coupled rooms is developed and compared with measurements for a 1:10 scale model and for Bass Hall, Ft. Worth, TX. At high frequencies, prior statistical-acoustics models are improved by geometrical-acoustics corrections for decay within sub-rooms and for energy transfer between sub-rooms. Comparisons of computational geometrical acoustics predictions based on beam-axis tracing with scale model measurements indicate errors resulting from tail-correction assuming constant quadratic growth of reflection density. Using ray tracing in the late part corrects this error. For mid-frequencies, the models are modified to account for wave effects at coupling apertures by including power transmission coefficients. Similarly, statical-acoustics models are improved through more accurate estimates of power transmission measurements. Scale model measurements are in accord with the predicted behavior. The edge-diffraction model is adapted to study transmission through apertures. Multiple-order scattering is theoretically and experimentally shown inaccurate due to neglect of slope diffraction. At low frequencies, perturbation models qualitatively explain scale model measurements. Measurements confirm relation of coupling strength to unperturbed pressure distribution on coupling surfaces. Measurements in Bass Hall exhibit effects of the coupled stage house. High frequency predictions of statistical acoustics and geometrical acoustics models and predictions of coupling apertures all agree with measurements.

  11. Studies into abnormal aggression in humans and rodents: Methodological and translational aspects.

    PubMed

    Haller, Jozsef

    2017-05-01

    Here we review the principles based on which aggression is rendered abnormal in humans and laboratory rodents, and comparatively overview the main methodological approaches based on which this behavior is studied in the two categories of subjects. It appears that the discriminating property of abnormal aggression is rule breaking, which renders aggression dysfunctional from the point of view of the perpetrator. We show that rodent models of abnormal aggression were created by the translation of human conditions into rodent equivalents, and discuss how findings obtained with such models may be "translated back" to human conditions when the mechanisms underlying aggression and its possibilities of treatment are investigated. We suggest that the complementary nature of human and rodent research approaches invite a more intense cross-talk between the two sides of aggression research than the one presently observed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Correlates of Recent Declines of Rodents in Northern and Southern Australia: Habitat Structure Is Critical

    PubMed Central

    Lawes, Michael J.; Fisher, Diana O.; Johnson, Chris N.; Blomberg, Simon P.; Frank, Anke S. K.; Fritz, Susanne A.; McCallum, Hamish; VanDerWal, Jeremy; Abbott, Brett N.; Legge, Sarah; Letnic, Mike; Thomas, Colette R.; Thurgate, Nikki; Fisher, Alaric; Gordon, Iain J.; Kutt, Alex

    2015-01-01

    Australia has experienced dramatic declines and extinctions of its native rodent species over the last 200 years, particularly in southern Australia. In the tropical savanna of northern Australia significant declines have occurred only in recent decades. The later onset of these declines suggests that the causes may differ from earlier declines in the south. We examine potential regional effects (northern versus southern Australia) on biological and ecological correlates of range decline in Australian rodents. We demonstrate that rodent declines have been greater in the south than in the tropical north, are strongly influenced by phylogeny, and are consistently greater for species inhabiting relatively open or sparsely vegetated habitat. Unlike in marsupials, where some species have much larger body size than rodents, body mass was not an important predictor of decline in rodents. All Australian rodent species are within the prey-size range of cats (throughout the continent) and red foxes (in the south). Contrary to the hypothesis that mammal declines are related directly to ecosystem productivity (annual rainfall), our results are consistent with the hypothesis that disturbances such as fire and grazing, which occur in non-rainforest habitats and remove cover used by rodents for shelter, nesting and foraging, increase predation risk. We agree with calls to introduce conservation management that limits the size and intensity of fires, increases fire patchiness and reduces grazing impacts at ecological scales appropriate for rodents. Controlling feral predators, even creating predator-free reserves in relatively sparsely-vegetated habitats, is urgently required to ensure the survival of rodent species, particularly in northern Australia where declines are not yet as severe as those in the south. PMID:26111037

  13. Correlates of Recent Declines of Rodents in Northern and Southern Australia: Habitat Structure Is Critical.

    PubMed

    Lawes, Michael J; Fisher, Diana O; Johnson, Chris N; Blomberg, Simon P; Frank, Anke S K; Fritz, Susanne A; McCallum, Hamish; VanDerWal, Jeremy; Abbott, Brett N; Legge, Sarah; Letnic, Mike; Thomas, Colette R; Thurgate, Nikki; Fisher, Alaric; Gordon, Iain J; Kutt, Alex

    2015-01-01

    Australia has experienced dramatic declines and extinctions of its native rodent species over the last 200 years, particularly in southern Australia. In the tropical savanna of northern Australia significant declines have occurred only in recent decades. The later onset of these declines suggests that the causes may differ from earlier declines in the south. We examine potential regional effects (northern versus southern Australia) on biological and ecological correlates of range decline in Australian rodents. We demonstrate that rodent declines have been greater in the south than in the tropical north, are strongly influenced by phylogeny, and are consistently greater for species inhabiting relatively open or sparsely vegetated habitat. Unlike in marsupials, where some species have much larger body size than rodents, body mass was not an important predictor of decline in rodents. All Australian rodent species are within the prey-size range of cats (throughout the continent) and red foxes (in the south). Contrary to the hypothesis that mammal declines are related directly to ecosystem productivity (annual rainfall), our results are consistent with the hypothesis that disturbances such as fire and grazing, which occur in non-rainforest habitats and remove cover used by rodents for shelter, nesting and foraging, increase predation risk. We agree with calls to introduce conservation management that limits the size and intensity of fires, increases fire patchiness and reduces grazing impacts at ecological scales appropriate for rodents. Controlling feral predators, even creating predator-free reserves in relatively sparsely-vegetated habitats, is urgently required to ensure the survival of rodent species, particularly in northern Australia where declines are not yet as severe as those in the south.

  14. Intestinal Helminths in Different Species of Rodents in North Khorasan Province, Northeast of Iran

    PubMed Central

    ARZAMANI, Kourosh; SALEHI, Mitra; MOBEDI, Iraj; ADINEZADE, Amir; HASANPOUR, Hamid; ALAVINIA, Mohammad; DARVISH, Jamshid; SHIRZADI, Mohammad Reza; MOHAMMADI, Zeinolabedin

    2017-01-01

    Background: Rodents are an important source of zoonotic diseases for human. The aim of this study was to determine the infectivity of rodents with intestinal helminths in North Khorasan Province, Iran. Methods: One hundred and thirteen rodents were collected using different collection methods such as kill and live traps, digging of their burrow, filling of their hiding places with water and hand net during 2011–2013. Their alimentary canals were removed in the laboratory and helminths were determined in the department of parasitology, Tehran University of Medical Sciences. Results: Thirteen species of helminths parasites were found in 13 species of rodents, including Aspiculuris tetraptera, Hymenolepis diminuta, Nippostrongylus brasiliensis, Protospirura Seurat, Rictolaria ratti, Skrjabinitaenia lobata, Streptopharagus kuntzi, Syphacia obvelata, Taenia taeniaeformis, Trichuris muris, Cysticercus fasciolaris, Acanthocephal. spp and Trichuris spp. Some of them were reported for the first time in new host in Iran. S. obvelata and A. tetraptera were the most frequent parasites and P. Seurat, R. ratti and C. fasciolaris were found only in one rodent. Conclusion: This is the first study to investigate the intestinal parasites in rodents in this area. Among different species identified, some of helminths were reported in new host. PMID:28761488

  15. Intestinal Helminths in Different Species of Rodents in North Khorasan Province, Northeast of Iran.

    PubMed

    Arzamani, Kourosh; Salehi, Mitra; Mobedi, Iraj; Adinezade, Amir; Hasanpour, Hamid; Alavinia, Mohammad; Darvish, Jamshid; Shirzadi, Mohammad Reza; Mohammadi, Zeinolabedin

    2017-01-01

    Rodents are an important source of zoonotic diseases for human. The aim of this study was to determine the infectivity of rodents with intestinal helminths in North Khorasan Province, Iran. One hundred and thirteen rodents were collected using different collection methods such as kill and live traps, digging of their burrow, filling of their hiding places with water and hand net during 2011-2013. Their alimentary canals were removed in the laboratory and helminths were determined in the department of parasitology, Tehran University of Medical Sciences. Thirteen species of helminths parasites were found in 13 species of rodents, including Aspiculuris tetraptera, Hymenolepis diminuta, Nippostrongylus brasiliensis, Protospirura Seurat, Rictolaria ratti, Skrjabinitaenia lobata, Streptopharagus kuntzi, Syphacia obvelata, Taenia taeniaeformis, Trichuris muris, Cysticercus fasciolaris, Acanthocephal. spp and Trichuris spp . Some of them were reported for the first time in new host in Iran. S. obvelata and A. tetraptera were the most frequent parasites and P. Seurat, R. ratti and C. fasciolaris were found only in one rodent. This is the first study to investigate the intestinal parasites in rodents in this area. Among different species identified, some of helminths were reported in new host.

  16. The Immunology of Wild Rodents: Current Status and Future Prospects.

    PubMed

    Viney, Mark; Riley, Eleanor M

    2017-01-01

    Wild animals' immune responses contribute to their evolutionary fitness. These responses are moulded by selection to be appropriate to the actual antigenic environment in which the animals live, but without imposing an excessive energetic demand which compromises other component of fitness. But, exactly what these responses are, and how they compare with those of laboratory animals, has been little studied. Here, we review the very small number of published studies of immune responses of wild rodents, finding general agreement that their humoral (antibody) responses are highly elevated when compared with those of laboratory animals, and that wild rodents' cellular immune system reveals extensive antigenic exposure. In contrast, proliferative and cytokine responses of ex vivo -stimulated immune cells of wild rodents are typically depressed compared with those of laboratory animals. Collectively, these responses are appropriate to wild animals' lives, because the elevated responses reflect the cumulative exposure to infection, while the depressed proliferative and cytokine responses are indicative of effective immune homeostasis that minimizes immunopathology. A more comprehensive understanding of the immune ecology of wild animals requires (i) understanding the antigenic load to which wild animals are exposed, and identification of any key antigens that mould the immune repertoire, (ii) identifying immunoregulatory processes of wild animals and the events that induce them, and (iii) understanding the actual resource state of wild animals, and the immunological consequences that flow from this. Together, by extending studies of wild rodents, particularly addressing these questions (while drawing on our immunological understanding of laboratory animals), we will be better able to understand how rodents' immune responses contribute to their fitness in the wild.

  17. Rodent models of glaucoma and their applicability for drug discovery.

    PubMed

    Agarwal, Renu; Agarwal, Puneet

    2017-03-01

    Rodents have widely been used to represent glaucomatous changes both in the presence and absence of elevated intraocular pressure (IOP) as they offer clear advantages over other animal species. IOP elevation is commonly achieved by creating an obstruction in the aqueous outflow pathways, consequently leading to retinal ganglion cell and optic nerve (ON) damage, the hallmark of glaucoma. These changes may also be achieved in the absence of elevated IOP by directly inflicting injury to retina or ON. Areas covered: This paper presents a summary of currently used rodent models of glaucoma. The characteristics of these models from several studies are summarized. The benefits and shortcomings of these models are also discussed. Expert opinion: The choice of animal model that closely represents human disease is key for successful translational of preclinical research to clinical practice. Rodent models of rapid IOP elevation are likely to be least representative, whereas models such as steroid-induced glaucoma models more closely resemble the trabecular meshwork changes seen in glaucomatous human eyes. However, this model needs further characterization. Rodent models based on direct retinal and ON injury are also useful tools to investigate molecular mechanisms involved at the site of final common pathology and neuroprotective strategies.

  18. Anatomy and Histology of Rodent and Human Major Salivary Glands

    PubMed Central

    Amano, Osamu; Mizobe, Kenichi; Bando, Yasuhiko; Sakiyama, Koji

    2012-01-01

    Major salivary glands of both humans and rodents consist of three pairs of macroscopic glands: parotid, submandibular, and sublingual. These glands secrete serous, mucous or mixed saliva via the proper main excretory ducts connecting the glandular bodies with the oral cavity. A series of discoveries about the salivary ducts in the 17th century by Niels Stensen (1638–1686), Thomas Wharton (1614–1673), and Caspar Bartholin (1655–1738) established the concept of exocrine secretion as well as salivary glands. Recent investigations have revealed the endocrine functions of parotin and a variety of cell growth factors produced by salivary glands. The present review aims to describe macroscopic findings on the major salivary glands of rodents and the microscopic differences between those of humans and rodents, which review should be of interest to those researchers studying salivary glands. PMID:23209333

  19. 24 CFR 8.25 - Public housing and multi-family Indian housing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Public housing and multi-family... multi-family Indian housing. (a) Development and alteration of public housing and multi-family Indian...-family Indian housing. (2) The requirements of § 8.23 shall apply to public housing and multi-family...

  20. 24 CFR 8.25 - Public housing and multi-family Indian housing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false Public housing and multi-family... multi-family Indian housing. (a) Development and alteration of public housing and multi-family Indian...-family Indian housing. (2) The requirements of § 8.23 shall apply to public housing and multi-family...