40 CFR 231.4 - Public comments and hearings.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 404(c) PROCEDURES § 231.4 Public comments and hearings. (a) The Regional Administrator shall provide a... final determination and corrective action that could be taken to reduce the adverse impact of the discharge. All such comments shall be considered by the Regional Administrator or his designee in preparing...

40 CFR 231.4 - Public comments and hearings.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 404(c) PROCEDURES § 231.4 Public comments and hearings. (a) The Regional Administrator shall provide a... final determination and corrective action that could be taken to reduce the adverse impact of the discharge. All such comments shall be considered by the Regional Administrator or his designee in preparing...

7 CFR 2.31 - General Counsel.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Patent Office. (f) Represent the Department in formal rulemaking and adjudicatory proceedings held in... 7 Agriculture 1 2011-01-01 2011-01-01 false General Counsel. 2.31 Section 2.31 Agriculture Office... the Law Library, furnishing complete legal and legislative library services to the Office of the...

7 CFR 2.31 - General Counsel.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Patent Office. (f) Represent the Department in formal rulemaking and adjudicatory proceedings held in... 7 Agriculture 1 2013-01-01 2013-01-01 false General Counsel. 2.31 Section 2.31 Agriculture Office... the Law Library, furnishing complete legal and legislative library services to the Office of the...

7 CFR 2.31 - General Counsel.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Patent Office. (f) Represent the Department in formal rulemaking and adjudicatory proceedings held in... 7 Agriculture 1 2012-01-01 2012-01-01 false General Counsel. 2.31 Section 2.31 Agriculture Office... the Law Library, furnishing complete legal and legislative library services to the Office of the...

Stability Limits for Rubble Pile Asteroid Shapes

NASA Astrophysics Data System (ADS)

Scheeres, Daniel

2018-04-01

The stability of rubble pile asteroids are explored analytically, using simple models for their constituent components. Specifically, we look at the stability of spherical components resting and potentially rolling on each other as a function of their relative sizes, configuration and number. This talk will present some recent results in this problem. Of specific interest is a 5:1 limit on the elongation of a rubble pile body for stability, which is interestingly the same extreme elongation found for the first interstellar object. This limit is for a rubble pile consisting of stacked spheres, resting on each other in a straight line. If there are 5 or less bodies resting on each other in this configuration, there is an interval of spin rates for which the configuration is stable. If there are 6 or more bodies stacked as such, the spin rate for it to stabilize is beyond the spin rate at which it fissions. The talk will also explore additional results for different configurations of bodies resting on each other.

49 CFR 231.4 - Fixed-end low-side gondola and low-side hopper cars.

Code of Federal Regulations, 2013 CFR

2013-10-01

... cars. 231.4 Section 231.4 Transportation Other Regulations Relating to Transportation (Continued... Fixed-end low-side gondola and low-side hopper cars. (Cars with sides 36 inches or less above the floor are low-side cars.) (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see...

49 CFR 231.4 - Fixed-end low-side gondola and low-side hopper cars.

Code of Federal Regulations, 2014 CFR

2014-10-01

... cars. 231.4 Section 231.4 Transportation Other Regulations Relating to Transportation (Continued... Fixed-end low-side gondola and low-side hopper cars. (Cars with sides 36 inches or less above the floor are low-side cars.) (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see...

Disaggregation of small, cohesive rubble pile asteroids due to YORP

NASA Astrophysics Data System (ADS)

Scheeres, D. J.

2018-04-01

The implication of small amounts of cohesion within relatively small rubble pile asteroids is investigated with regard to their evolution under the persistent presence of the YORP effect. We find that below a characteristic size, which is a function of cohesive strength, density and other properties, rubble pile asteroids can enter a "disaggregation phase" in which they are subject to repeated fissions after which the formation of a stabilizing binary system is not possible. Once this threshold is passed rubble pile asteroids may be disaggregated into their constituent components within a finite time span. These constituent components will have their own spin limits - albeit potentially at a much higher spin rate due to the greater strength of a monolithic body. The implications of this prediction are discussed and include modification of size distributions, prevalence of monolithic bodies among meteoroids and the lifetime of small rubble pile bodies in the solar system. The theory is then used to place constraints on the strength of binary asteroids characterized as a function of their type.

Are cometary nuclei primordial rubble piles?

NASA Technical Reports Server (NTRS)

Weissman, P. R.

1986-01-01

Whipple's icy conglomerate model for the cometary nucleus has had considerable sucess in explaining a variety of cometary phenomena such as gas production rates and nongravitational forces. However, as discussed here, both observational evidence and theoretical considerations suggest that the cometary nucleus may not be a well-consolidated single body, but may instead be a loosely bound agglomeration of smaller fragments, weakly bonded and subject to occasional or even frequent disruptive events. The proposed model is analogous to the 'rubble pile' model suggested for the larger main-belt asteroids, although the larger cometary fragments are expected to be primordial condensations rather than collisionally derived debris as in the asteroid case. The concept of cometary nuclei as primordial rubble piles is proposed as a modification of the basic Whipple model, not as a replacement for it.

46 CFR 108.231 - Application.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Application. 108.231 Section 108.231 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Construction and Arrangement Helicopter Facilities § 108.231 Application. Sections 108.231 through 108.241...

Numerical Simulations of Microporous Body Disruptions: Comparison with Non-porous and Rubble-pile targets

NASA Astrophysics Data System (ADS)

Michel, Patrick; Jutzi, Martin; Richardson, Derek C.

2014-11-01

In recent years, we have shown by numerical impact simulations that collisions and gravitational reaccumulation together can explain the formation of asteroid families and satellites (e.g. [1]). We also found that the presence of microporosity influences the outcome of a catastrophic disruption ([2], [3]). The size-frequency distributions (SFDs) resulting from the disruption of 100 km-diameter targets consisting of either monolithic non-porous basalt or non-porous basalt blocks held together by gravity (termed rubble piles by the investigators) has already been determined ([4], [5]). Using the same wide range of collision speeds, impact angles, and impactor sizes, we extended those studies to targets consisting of porous material represented by parameters for pumice. Dark-type asteroid families, such as C-type, are often considered to contain a high fraction of porosity (including microporosity). To determine the impact conditions for dark-type asteroid family formation, a comparison is needed between the actual family SFD and that of impact disruptions of porous bodies. Moreover, the comparison between the disruptions of non-porous, rubble-pile, and porous targets is important to assess the influence of various internal structures on the outcome. Our results show that in terms of largest remnants, in general, the outcomes for porous bodies are more similar to the ones for non-porous targets ([4]) than for rubble-pile targets ([5]). In particular, the latter targets are much weaker (the largest remnants are much smaller). We suspect that this is because the pressure-dependent shear strength between the individual components of the rubble pile is not properly modeled, which makes the body behave more like a fluid than an actual rubble pile. We will present our results and implications in terms of SFDs as well as ejection velocities over the entire considered parameter space. We will also check whether we find good agreement with existing dark-type asteroid families

Etch pit investigation of free electron concentration controlled 4H-SiC

NASA Astrophysics Data System (ADS)

Kim, Hong-Yeol; Shin, Yun Ji; Kim, Jung Gon; Harima, Hiroshi; Kim, Jihyun; Bahng, Wook

2013-04-01

Etch pits were investigated using the molten KOH selective etching method to examine dependence of etch pit shape and size on free electron concentration. The free electron concentrations of highly doped 4H-silicon carbide (SiC) were controlled by proton irradiation and thermal annealing, which was confirmed by a frequency shift in the LO-phonon-plasmon-coupled (LOPC) mode on micro-Raman spectroscopy. The proton irradiated sample with 5×1015 cm-2 fluence and an intrinsic semi-insulating sample showed clearly classified etch pits but different ratios of threading screw dislocation (TSD) and threading edge dislocation (TED) sizes. Easily classified TEDs and TSDs on proton irradiated 4H-SiC were restored as highly doped 4H-SiC after thermal annealing due to the recovered carrier concentrations. The etched surface of proton irradiated 4H-SiC and boron implanted SiC showed different surface conditions after activation.

Eros is a Rubble Pile

NASA Astrophysics Data System (ADS)

Asphaug, Erik

2008-09-01

Asteroid 433 Eros is regarded as "fractured monolith" or "shatter pile". But models of fragmentation and disruption (e.g. Benz and Asphaug 1999) predict that any large rocky asteroid should be transformed into a jumble of dust, gravel, talus and boulders, simply because it is much easier to comminute an asteroid than to catastrophically disrupt it. Sometimes the relatively high density of Eros is taken as evidence for a fractured monolithic structure, although the inferred bulk porosity of Eros ( 20-30%) is what one expects for a rubble pile, and is about the porosity of sand and talus. The focus here is that a rubble pile structure is contraindicated by the pronounced network of linear fault-like structures (Buczkowski et al. 2008), some of which radiate from recent large impacts such as Psyche, and which form rectangular boundaries around some of the medium-sized craters. This needs an explanation. Here it is proposed, and quantitatively addressed, that the majority of these faults occur just in the upper tens of meters, where cohesion exceeds gravitational stress even for loose piles of lunar-like regolith. Assuming Eros regolith has the cohesion ( 1 kPa) measured for lunar regolith, then faulting is expected to a depth of 10 m, directly analogous to how faults occur in the upper layers of beach sand. The fact that Eros has few steep slopes anywhere, except for the angles of repose within its craters, at a baseline of 100 m (Zuber et al. 2002), is satisfied by the hypothesis that Eros is a rubble pile rather than a shattered monolith. The low fault stress implied by the above, supports the findings of dense networks of linear structures, ubiquitous features which are otherwise difficult to explain as fractures in a rocky target which has not been disrupted or jumbled against its very low gravity.

Lithifying Microbes Associated to Coral Rubbles

NASA Astrophysics Data System (ADS)

Beltran, Y.

2015-12-01

Microbial communities taking part in calcium carbonate lithification processes are particularly relevant to coral reef formation in as much as this lithification allows the stabilization of secondary reef structure. This second framework promotes long-term permanence of the reef, favoring the establishment of macro-reef builders, including corals. The reef-bacterial crusts formed by microbial communities are composed of magnesium calcite. Although prokaryotes are not proper calcifiers, carbonate precipitation can be induced by their metabolic activity and EPS production. Coral reefs are rapidly declining due to several variables associated to environmental change. Specifically in the Caribbean, stony coral Acropora palmata have suffered damage due to diseases, bleaching and storms. Some reports show that in highly disturbed areas wide ridges of reef rubbles are formed by biological and physical lithification. In this study we explore microbial diversity associated to lithified rubbles left after the great decline of reef-building A. palmata.

4. Unit 4 Turbine Pit Oil Jacking Pump and Wicket ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Unit 4 Turbine Pit Oil Jacking Pump and Wicket Gate Linkages, view to the north. The jacking pump, located along the wall on the left side of photograph, is used for pumping oil to lift the thrust bearing prior to starting the unit. Note the wicket gate linkages attached to the operating ring and visible in the lower center of the photograph. - Washington Water Power Clark Fork River Cabinet Gorge Hydroelectric Development, Powerhouse, North Bank of Clark Fork River at Cabinet Gorge, Cabinet, Bonner County, ID

Dose-Dependent Dual Role of PIT-1 (POU1F1) in Somatolactotroph Cell Proliferation and Apoptosis

PubMed Central

Jullien, Nicolas; Roche, Catherine; Brue, Thierry; Figarella-Branger, Dominique; Graillon, Thomas; Barlier, Anne; Herman, Jean-Paul

2015-01-01

To test the role of wtPIT-1 (PITWT) or PIT-1 (R271W) (PIT271) in somatolactotroph cells, we established, using inducible lentiviral vectors, sublines of GH4C1 somatotroph cells that allow the blockade of the expression of endogenous PIT-1 and/or the expression of PITWT or PIT271, a dominant negative mutant of PIT-1 responsible for Combined Pituitary Hormone Deficiency in patients. Blocking expression of endogenous PIT-1 induced a marked decrease of cell proliferation. Overexpressing PITWT twofold led also to a dose-dependent decrease of cell proliferation that was accompanied by cell death. Expression of PIT271 induced a strong dose-dependent decrease of cell proliferation accompanied by a very pronounced cell death. These actions of PIT271 are independent of its interaction/competition with endogenous PIT-1, as they were unchanged when expression of endogenous PIT-1 was blocked. All these actions are specific for somatolactotroph cells, and could not be observed in heterologous cells. Cell death induced by PITWT or by PIT271 was accompanied by DNA fragmentation, but was not inhibited by inhibitors of caspases, autophagy or necrosis, suggesting that this cell death is a caspase-independent apoptosis. Altogether, our results indicate that under normal conditions PIT-1 is important for the maintenance of cell proliferation, while when expressed at supra-normal levels it induces cell death. Through this dual action, PIT-1 may play a role in the expansion/regression cycles of pituitary lactotroph population during and after lactation. Our results also demonstrate that the so-called “dominant-negative” action of PIT271 is independent of its competition with PIT-1 or a blockade of the actions of the latter, and are actions specific to this mutant variant of PIT-1. PMID:25822178

Autonomous robotic platforms for locating radio sources buried under rubble

NASA Astrophysics Data System (ADS)

Tasu, A. S.; Anchidin, L.; Tamas, R.; Paun, M.; Danisor, A.; Petrescu, T.

2016-12-01

This paper deals with the use of autonomous robotic platforms able to locate radio signal sources such as mobile phones, buried under collapsed buildings as a result of earthquakes, natural disasters, terrorism, war, etc. This technique relies on averaging position data resulting from a propagation model implemented on the platform and the data acquired by robotic platforms at the disaster site. That allows us to calculate the approximate position of radio sources buried under the rubble. Based on measurements, a radio map of the disaster site is made, very useful for locating victims and for guiding specific rubble lifting machinery, by assuming that there is a victim next to a mobile device detected by the robotic platform; by knowing the approximate position, the lifting machinery does not risk to further hurt the victims. Moreover, by knowing the positions of the victims, the reaction time is decreased, and the chances of survival for the victims buried under the rubble, are obviously increased.

Rotational Failure of Rubble-pile Bodies: Influences of Shear and Cohesive Strengths

NASA Astrophysics Data System (ADS)

Zhang, Yun; Richardson, Derek C.; Barnouin, Olivier S.; Michel, Patrick; Schwartz, Stephen R.; Ballouz, Ronald-Louis

2018-04-01

The shear and cohesive strengths of a rubble-pile asteroid could influence the critical spin at which the body fails and its subsequent evolution. We present results using a soft-sphere discrete element method to explore the mechanical properties and dynamical behaviors of self-gravitating rubble piles experiencing increasing rotational centrifugal forces. A comprehensive contact model incorporating translational and rotational friction and van der Waals cohesive interactions is developed to simulate rubble-pile asteroids. It is observed that the critical spin depends strongly on both the frictional and cohesive forces between particles in contact; however, the failure behaviors only show dependence on the cohesive force. As cohesion increases, the deformation of the simulated body prior to disruption is diminished, the disruption process is more abrupt, and the component size of the fissioned material is increased. When the cohesive strength is high enough, the body can disaggregate into similar-size fragments, which could be a plausible mechanism to form asteroid pairs or active asteroids. The size distribution and velocity dispersion of the fragments in high-cohesion simulations show similarities to the disintegrating asteroid P/2013 R3, indicating that this asteroid may possess comparable cohesion in its structure and experience rotational fission in a similar manner. Additionally, we propose a method for estimating a rubble pile’s friction angle and bulk cohesion from spin-up numerical experiments, which provides the opportunity for making quantitative comparisons with continuum theory. The results show that the present technique has great potential for predicting the behaviors and estimating the material strengths of cohesive rubble-pile asteroids.

Jahn-Teller effect on the [TiF 4F 4F int] 6-(C 4v) and [NiF 4F 4F int] 7-(C 4v) clusters embedded into SrF 2 crystals

NASA Astrophysics Data System (ADS)

Ulanov, V. A.; Zhiteitcev, E. R.; Varlamov, A. G.

2007-07-01

By means of EPR method the associative [TiF 4F 4F int] 6-(C 4v) and [NiF 4F 4F int] 7-(C 4v) centers were revealed in the fluorite type SrF 2:Ti and SrF 2:Ni crystals grown by Bridgman method in helium atmosphere containing some amount of a fluorine gas. It was found that at low temperatures the local structures of these associative centers were exposed to a static rhombic distortion. The reasons of such distortions were accounted for by the assumption that the E ⊗ ( b1 + b2) vibronic interaction became effective due to that the ground orbital states of the [TiF 4F 4F int] 6-(C 4v) and [NiF 4F 4F int] 7-(C 4v) centers occurred to be doubly degenerated.

Simulations of impacts on rubble-pile asteroids

NASA Astrophysics Data System (ADS)

Deller, J.; Snodgrass, C.; Lowry, S.; Price, M.; Sierks, H.

2014-07-01

Rubble-pile asteroids can contain a high level of macroporosity. For some asteroids, porosities of 40 % or even more have been measured [1]. While little is known about the exact distribution of the voids inside rubble-pile asteroids, assumptions have to be made for the modeling of impact events on these bodies. Most hydrocodes do not distinguish between micro- and macroporosity, instead describing brittle material by a constitutive model as homogeneous. We developed a method to model rubble-pile structures in hypervelocity impact events explicitly. The formation of the asteroid is modelled as a gravitational aggregation of spherical `pebbles', that form the building blocks of our target. This aggregate is then converted into a high-resolution Smoothed Particle Hydrodynamics (SPH) model, which also accounts for macroporosity inside the pebbles. We present results of a study that quantifies the influence of our model parameters on the outcome of a typical impact event of two small main-belt asteroids. The existence of void space in our model increases the resistance against collisional disruption, a behavior observed before [2]. We show that for our model no a priori knowledge of the rubble-pile constituents in the asteroid is needed, as the choice of the corresponding parameters does not directly correlate with the impact outcome. The size distribution of the pebbles used as building blocks in the formation of an asteroid is only poorly constrained. As a starting point, we use a power law N(>r) ∝ r^α to describe the distribution of radii of the pebbles. Reasonable values for the slope α range around α=-2.5, as found in the size distribution of main-belt objects [3,4]. The cut-off values for pebbles, r_{min} and r_{max} are given by practical considerations: In the SPH formalism, properties are represented by weighted averages of particles within their smoothing length h, preventing the resolution of structures below that scale. Using spheres with radius in the

49 CFR 234.231 - Fouling wires.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Fouling wires. 234.231 Section 234.231..., Inspection, and Testing Maintenance Standards § 234.231 Fouling wires. Each set of fouling wires in a highway... single duplex wire with single plug acting as fouling wires is prohibited. Existing installations having...

49 CFR 234.231 - Fouling wires.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Fouling wires. 234.231 Section 234.231..., Inspection, and Testing Maintenance Standards § 234.231 Fouling wires. Each set of fouling wires in a highway... single duplex wire with single plug acting as fouling wires is prohibited. Existing installations having...

First Rescue Under the Rubble: The Medical Aid in the First Hours After the Earthquake in Amatrice (Italy) on August 24, 2016.

PubMed

Blasetti, Angelo Geremia; Petrucci, Emiliano; Cofini, Vincenza; Pizzi, Barbara; Scimia, Paolo; Pozone, Tullio; Necozione, Stefano; Fusco, Pierfrancesco; Marinangeli, Franco

2018-02-01

Specific Event Identifiers a. Event Type: Earthquake measuring 6.2 (SD=0.016) on the moment magnitude; b. Event Onset: August 24, 2016 - 03:36:32 CEST (01:36 UTC); c. Location of Event: Central Italy, in the town of Amatrice; d. Geographic Coordinates: latitude (DMS): 42°37'45.77″N; longitude (DMS): 13°17'18.14″E; elevation: 955 meters above sea-level; e. Dates: August 24, 2016 at 4:48 AM; f. Response Type: Medical Relief. On August 24, 2016, an earthquake hit the town of Amatrice (Italy). This study aims to document the first medical aid provided to earthquake victims in Amatrice immediately following the earthquake. Patient data were collected and recorded during the first clinical evaluation and before definitive hospitalization. Blood gas tests were performed on survivors extricated from the rubble using the iSTAT (Abbott Point of Care Inc.; Princeton, New Jersey USA) handheld blood analyzer. Performing "victim-side" blood gas tests could provide concrete information to facilitate clinical evaluation and decision making when treating buried victims. After a natural disaster, it is essential to provide effective analgo-sedation to victims. Blasetti AG , Petrucci E , Cofini V , Pizzi B , Scimia P , Pozone T , Necozione S , Fusco P , Marinangeli F . First rescue under the rubble: the medical aid in the first hours after the earthquake in Amatrice (Italy) on August 24, 2016. Prehosp Disaster Med. 2018;33(1):109-113.

Integrated and holistic suitability assessment of recycling options for masonry rubble

NASA Astrophysics Data System (ADS)

Herbst, T.; Rübner, K.; Meng, B.

2012-04-01

Our industrial society depends on continuous mining and consumption of raw materials and energy. Besides, the building sector causes one of the largest material streams in Germany. On the one hand, the building sector is connected with a high need in material and energetic resources as well as financial expenditures. On the other hand, nearly 50 % of the volume of waste arises from the building industry. During the last years, the limitation of natural resources, increasing negative environmental consequences as well as rising prices and shortages of dump space have led to a change in thinking in the building and waste industry to a closed substance cycle waste management. In consideration of the production figures of the main kinds of masonry units (clay bricks, sand-lime bricks, autoclaved aerated concrete brick, concrete blocks), a not unimportant quantity of masonry rubble (including gypsum plaster boards, renders, mortars and mineral insulating materials) of more than 20 million tons per year is generated in the medium term. With regard to a sustainable closed substance cycle waste management, these rest masses have to be recycled if possible. Processed aggregates made from masonry rubble can be recycled in the production of new masonry units under certain conditions. Even carefully deconstructed masonry units can once more re-used as masonry units, particularly in the area of the preservation of monuments and historical buildings. In addition, masonry rubble in different processing qualities is applied in earth and road construction, horticulture and scenery construction as well as concrete production. The choice of the most suitable recycling option causes technical, economical and ecological questions. At present, a methodology for a comprehensive suitability assessment with a passable scope of work does not exist. Basic structured and structuring information on the recycling of masonry rubble is absent up to now. This as well as the economic and technical

10 CFR 600.231 - Real property.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Real property. 600.231 Section 600.231 Energy DEPARTMENT....231 Real property. (a) Title. Subject to the obligations and conditions set forth in this section, title to real property acquired under a grant or subgrant will vest upon acquisition in the grantee or...

10 CFR 600.231 - Real property.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Real property. 600.231 Section 600.231 Energy DEPARTMENT....231 Real property. (a) Title. Subject to the obligations and conditions set forth in this section, title to real property acquired under a grant or subgrant will vest upon acquisition in the grantee or...

10 CFR 600.231 - Real property.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Real property. 600.231 Section 600.231 Energy DEPARTMENT....231 Real property. (a) Title. Subject to the obligations and conditions set forth in this section, title to real property acquired under a grant or subgrant will vest upon acquisition in the grantee or...

10 CFR 600.231 - Real property.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Real property. 600.231 Section 600.231 Energy DEPARTMENT....231 Real property. (a) Title. Subject to the obligations and conditions set forth in this section, title to real property acquired under a grant or subgrant will vest upon acquisition in the grantee or...

10 CFR 600.231 - Real property.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Real property. 600.231 Section 600.231 Energy DEPARTMENT....231 Real property. (a) Title. Subject to the obligations and conditions set forth in this section, title to real property acquired under a grant or subgrant will vest upon acquisition in the grantee or...

Martian Central Pit Craters

NASA Technical Reports Server (NTRS)

Hillman, E.; Barlow, N. G.

2005-01-01

Impact craters containing central pits are rare on the terrestrial planets but common on icy bodies. Mars is the exception among the terrestrial planets, where central pits are seen on crater floors ( floor pits ) as well as on top of central peaks ( summit pits ). Wood et al. [1] proposed that degassing of subsurface volatiles during crater formation produced central pits. Croft [2] argued instead that central pits might form during the impact of volatile-rich comets. Although central pits are seen in impact craters on icy moons such as Ganymede, they do show some significant differences from their martian counterparts: (a) only floor pits are seen on Ganymede, and (b) central pits begin to occur at crater diameters where the peak ring interior morphology begins to appear in terrestrial planet craters [3]. A study of craters containing central pits was conducted by Barlow and Bradley [4] using Viking imagery. They found that 28% of craters displaying an interior morphology on Mars contain central pits. Diameters of craters containing central pits ranged from 16 to 64 km. Barlow and Bradley noted that summit pit craters tended to be smaller than craters containing floor pits. They also noted a correlation of central pit craters with the proposed rings of large impact basins. They argued that basin ring formation fractured the martian crust and allowed subsurface volatiles to concentrate in these locations. They favored the model that degassing of the substrate during crater formation was responsible for central pit formation due to the preferential location of central pit craters along these basin rings.

Polyhedron Modeling of Rubble-Pile Asteroids

NASA Technical Reports Server (NTRS)

Korycansky, D. G.; Asphaug, E.

2005-01-01

We report on progress in modeling of asteroids as collections of rigid polyhedra ("rubble piles"). Such models are (idealized) candidates for asteroid structures: aggregates of irregular rocky subunits that are held together by self-gravity and friction. We have taken several steps toward greater realism and physical interest in construction of the models (although the gravitational fields are being treated in a simplified manner). -

4. VIEW OF TURBINE PIT AT UNIT 3 SHOWING SERVOMOTOR ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. VIEW OF TURBINE PIT AT UNIT 3 SHOWING SERVO-MOTOR HEADS (BACKGROUND AT CENTER) WITH PISTON RODS BOLTED TO TURBINE GATE OPERATION RING (CENTER AT LEFT AND CENTER AT RIGHT). VIEW TO THE NORTH-NORTHWEST. - Black Eagle Hydroelectric Facility, Powerhouse, Great Falls, Cascade County, MT

49 CFR 231.6 - Flat cars.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Flat cars. 231.6 Section 231.6 Transportation... TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.6 Flat cars. (Cars with sides 12 inches or less above the floor may be equipped the same as flat cars.) (a) Hand brakes—(1) Number. Same as specified for...

49 CFR 231.6 - Flat cars.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Flat cars. 231.6 Section 231.6 Transportation... TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.6 Flat cars. (Cars with sides 12 inches or less above the floor may be equipped the same as flat cars.) (a) Hand brakes—(1) Number. Same as specified for...

49 CFR 231.6 - Flat cars.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Flat cars. 231.6 Section 231.6 Transportation... TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.6 Flat cars. (Cars with sides 12 inches or less above the floor may be equipped the same as flat cars.) (a) Hand brakes—(1) Number. Same as specified for...

49 CFR 231.6 - Flat cars.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Flat cars. 231.6 Section 231.6 Transportation... TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.6 Flat cars. (Cars with sides 12 inches or less above the floor may be equipped the same as flat cars.) (a) Hand brakes—(1) Number. Same as specified for...

49 CFR 231.6 - Flat cars.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Flat cars. 231.6 Section 231.6 Transportation... TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.6 Flat cars. (Cars with sides 12 inches or less above the floor may be equipped the same as flat cars.) (a) Hand brakes—(1) Number. Same as specified for...

49 CFR 231.21 - Tank cars without underframes.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Tank cars without underframes. 231.21 Section 231... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.21 Tank cars without underframes. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1...

49 CFR 231.11 - Caboose cars without platforms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Caboose cars without platforms. 231.11 Section 231... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.11 Caboose cars without platforms. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1...

49 CFR 231.21 - Tank cars without underframes.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Tank cars without underframes. 231.21 Section 231... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.21 Tank cars without underframes. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1...

49 CFR 231.21 - Tank cars without underframes.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Tank cars without underframes. 231.21 Section 231... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.21 Tank cars without underframes. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1...

49 CFR 231.11 - Caboose cars without platforms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Caboose cars without platforms. 231.11 Section 231... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.11 Caboose cars without platforms. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1...

49 CFR 231.11 - Caboose cars without platforms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Caboose cars without platforms. 231.11 Section 231... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.11 Caboose cars without platforms. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1...

49 CFR 231.21 - Tank cars without underframes.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Tank cars without underframes. 231.21 Section 231... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.21 Tank cars without underframes. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1...

49 CFR 231.11 - Caboose cars without platforms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Caboose cars without platforms. 231.11 Section 231... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.11 Caboose cars without platforms. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1...

49 CFR 231.21 - Tank cars without underframes.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Tank cars without underframes. 231.21 Section 231... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.21 Tank cars without underframes. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1...

49 CFR 231.11 - Caboose cars without platforms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Caboose cars without platforms. 231.11 Section 231... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.11 Caboose cars without platforms. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1...

49 CFR 231.10 - Caboose cars with platforms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Caboose cars with platforms. 231.10 Section 231.10..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.10 Caboose cars with platforms. Note: a. The term “bottom of car” as used in § 231.10 is construed to mean “bottom of side-sill or...

49 CFR 231.10 - Caboose cars with platforms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Caboose cars with platforms. 231.10 Section 231.10..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.10 Caboose cars with platforms. Note: a. The term “bottom of car” as used in § 231.10 is construed to mean “bottom of side-sill or...

49 CFR 231.10 - Caboose cars with platforms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Caboose cars with platforms. 231.10 Section 231.10..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.10 Caboose cars with platforms. Note: a. The term “bottom of car” as used in § 231.10 is construed to mean “bottom of side-sill or...

49 CFR 231.10 - Caboose cars with platforms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Caboose cars with platforms. 231.10 Section 231.10..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.10 Caboose cars with platforms. Note: a. The term “bottom of car” as used in § 231.10 is construed to mean “bottom of side-sill or...

49 CFR 231.10 - Caboose cars with platforms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Caboose cars with platforms. 231.10 Section 231.10..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.10 Caboose cars with platforms. Note: a. The term “bottom of car” as used in § 231.10 is construed to mean “bottom of side-sill or...

Small asteroids - rubble piles or boulders?

NASA Astrophysics Data System (ADS)

Harris, Alan W.

2013-10-01

The asteroid rotation spin barrier at ~2.2 h period among asteroids 10 km > D > 200 m doesn’t prove all such asteroids are rubble piles, and the faster rotations among smaller asteroids doesn’t require monolithic strength, either. Only a very modest strength, perhaps no more than van der Waals force, might suffice to hold regolith together on a small super-fast rotator (Sanchez & Scheeres, 2013, arXif:1306.1622v1). The problem is that for a constant or only slowly varying strength with respect to diameter, the spin barrier becomes proportional to 1/D below the size where material strength is dominant, or perhaps a bit steeper if strength increases with decreasing D. What we observe in the distribution of asteroid spins versus diameter is that below D ~ 200 m, the spin barrier goes up at least ~D-3.5, if not abruptly. Models with constant or slowly varying strength fail to fit this observation, and the abrupt transition cannot be an observational selection effect: the void in the phase space of rotations would be among the easiest rotations to observe, e.g. the one conspicuous exception, 2001 OE84 (D ~ 0.7 km, P = 0.5 h) was easily and unambiguously measured (Pravec, et al. 2002, Proc. ACM 2002, ESA SP-500, 743-745). This abrupt transition is most easily explained as a real transition in material properties of asteroids in the size range ~200 m diameter, from “rubble pile” to “boulder”, although neither term may be fully descriptive of the actual structure. Two other lines of evidence suggest that this transition in properties is real: the dip in the size-frequency distribution of NEAs is maximum at ~150 m, suggesting that a transition to stronger material structure occurs about there, and we observe, e.g., Tunguska and the recent Chelyabinsk bolide, that bodies in the tens of meters size range entering the atmosphere behave more like solid rocks than rock piles (Boslough & Crawford 2008, Int. J. Imp. Eng. 35, 1441-1448). I encourage those doing computer

49 CFR 231.0 - Applicability and penalties.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Applicability and penalties. 231.0 Section 231.0..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.0 Applicability and penalties. (a... requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at...

49 CFR 231.0 - Applicability and penalties.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Applicability and penalties. 231.0 Section 231.0..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.0 Applicability and penalties. (a... requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at...

49 CFR 231.0 - Applicability and penalties.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Applicability and penalties. 231.0 Section 231.0..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.0 Applicability and penalties. (a... requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at...

49 CFR 231.0 - Applicability and penalties.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Applicability and penalties. 231.0 Section 231.0..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.0 Applicability and penalties. (a... requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at...

49 CFR 231.20 - Variation in size permitted.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Variation in size permitted. 231.20 Section 231.20 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.20 Variation in size permitted. To...

Stability of binaries. Part II: Rubble-pile binaries

NASA Astrophysics Data System (ADS)

Sharma, Ishan

2016-10-01

We consider the stability of the binary asteroids whose members are granular aggregates held together by self-gravity alone. A binary is said to be stable whenever both its members are orbitally and structurally stable to both orbital and structural perturbations. To this end, we extend the stability analysis of Sharma (Sharma [2015] Icarus, 258, 438-453), that is applicable to binaries with rigid members, to the case of binary systems with rubble members. We employ volume averaging (Sharma et al. [2009] Icarus, 200, 304-322), which was inspired by past work on elastic/fluid, rotating and gravitating ellipsoids. This technique has shown promise when applied to rubble-pile ellipsoids, but requires further work to settle some of its underlying assumptions. The stability test is finally applied to some suspected binary systems, viz., 216 Kleopatra, 624 Hektor and 90 Antiope. We also see that equilibrated binaries that are close to mobilizing their maximum friction can sustain only a narrow range of shapes and, generally, congruent shapes are preferred.

Cohesive forces prevent the rotational breakup of rubble-pile asteroid (29075) 1950 DA.

PubMed

Rozitis, Ben; MacLennan, Eric; Emery, Joshua P

2014-08-14

Space missions and ground-based observations have shown that some asteroids are loose collections of rubble rather than solid bodies. The physical behaviour of such 'rubble-pile' asteroids has been traditionally described using only gravitational and frictional forces within a granular material. Cohesive forces in the form of small van der Waals forces between constituent grains have recently been predicted to be important for small rubble piles (ten kilometres across or less), and could potentially explain fast rotation rates in the small-asteroid population. The strongest evidence so far has come from an analysis of the rotational breakup of the main-belt comet P/2013 R3 (ref. 7), although that was indirect and poorly constrained by observations. Here we report that the kilometre-sized asteroid (29075) 1950 DA (ref. 8) is a rubble pile that is rotating faster than is allowed by gravity and friction. We find that cohesive forces are required to prevent surface mass shedding and structural failure, and that the strengths of the forces are comparable to, though somewhat less than, the forces found between the grains of lunar regolith.

10. DETAIL OF RUBBLE MASONRY ABUTMENT ON THE SOUTH BANK ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. DETAIL OF RUBBLE MASONRY ABUTMENT ON THE SOUTH BANK AND DISINTEGRATING CONCRETE FACING; VIEW FROM WEST. - Mitchell's Mill Bridge, Spanning Winter's Run on Carrs Mill Road, west of Bel Air, Bel Air, Harford County, MD

49 CFR 231.18 - Cars of special construction.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Cars of special construction. 231.18 Section 231... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.18 Cars of special construction. Cars of construction not covered specifically in the foregoing sections in this part, relative to...

49 CFR 231.18 - Cars of special construction.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Cars of special construction. 231.18 Section 231... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.18 Cars of special construction. Cars of construction not covered specifically in the foregoing sections in this part, relative to...

49 CFR 231.18 - Cars of special construction.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Cars of special construction. 231.18 Section 231... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.18 Cars of special construction. Cars of construction not covered specifically in the foregoing sections in this part, relative to...

49 CFR 231.18 - Cars of special construction.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Cars of special construction. 231.18 Section 231... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.18 Cars of special construction. Cars of construction not covered specifically in the foregoing sections in this part, relative to...

49 CFR 231.18 - Cars of special construction.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Cars of special construction. 231.18 Section 231... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.18 Cars of special construction. Cars of construction not covered specifically in the foregoing sections in this part, relative to...

49 CFR 231.7 - Tank cars with side platforms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Tank cars with side platforms. 231.7 Section 231.7..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.7 Tank cars with side platforms. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2...

49 CFR 231.7 - Tank cars with side platforms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Tank cars with side platforms. 231.7 Section 231.7..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.7 Tank cars with side platforms. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2...

49 CFR 231.9 - Tank cars without end sills.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Tank cars without end sills. 231.9 Section 231.9..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.9 Tank cars without end sills. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2...

49 CFR 231.7 - Tank cars with side platforms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Tank cars with side platforms. 231.7 Section 231.7..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.7 Tank cars with side platforms. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2...

49 CFR 231.9 - Tank cars without end sills.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Tank cars without end sills. 231.9 Section 231.9..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.9 Tank cars without end sills. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2...

49 CFR 231.7 - Tank cars with side platforms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Tank cars with side platforms. 231.7 Section 231.7..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.7 Tank cars with side platforms. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2...

49 CFR 231.9 - Tank cars without end sills.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Tank cars without end sills. 231.9 Section 231.9..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.9 Tank cars without end sills. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2...

49 CFR 231.9 - Tank cars without end sills.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Tank cars without end sills. 231.9 Section 231.9..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.9 Tank cars without end sills. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2...

49 CFR 231.7 - Tank cars with side platforms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Tank cars with side platforms. 231.7 Section 231.7..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.7 Tank cars with side platforms. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2...

49 CFR 231.9 - Tank cars without end sills.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Tank cars without end sills. 231.9 Section 231.9..., DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.9 Tank cars without end sills. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2...

FEATURE A. CONCRETE ANTIAIRCRAFT GUN POSITION, SHOWING CORAL RUBBLE BERM, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

FEATURE A. CONCRETE ANTI-AIRCRAFT GUN POSITION, SHOWING CORAL RUBBLE BERM, VIEW FACING SOUTHEAST. - Naval Air Station Barbers Point, Battery-Anti-Aircraft Gun Position, South of Point Cruz Road & west of Coral Sea Road, Ewa, Honolulu County, HI

8. VIEW, LOOKING SOUTHEAST OF RUBBLE MASONRY PIER AT END ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. VIEW, LOOKING SOUTHEAST OF RUBBLE MASONRY PIER AT END OF EAST INTAKE CHANNEL WALL, WITH SOUTH GUARDLOCK END BEYOND - Dundee Canal, Headgates, Guardlock & Uppermost Section, 250 feet northeast of Randolph Avenue, opposite & in line with East Clifton Avenue, Clifton, Passaic County, NJ

Thermodynamic assessment of the LiF-ThF4-PuF3-UF4 system

NASA Astrophysics Data System (ADS)

Capelli, E.; Beneš, O.; Konings, R. J. M.

2015-07-01

The LiF-ThF4-PuF3-UF4 system is the reference salt mixture considered for the Molten Salt Fast Reactor (MSFR) concept started with PuF3. In order to obtain the complete thermodynamic description of this quaternary system, two binary systems (ThF4-PuF3 and UF4-PuF3) and two ternary systems (LiF-ThF4-PuF3 and LiF-UF4-PuF3) have been assessed for the first time. The similarities between CeF3/PuF3 and ThF4/UF4 compounds have been taken into account for the presented optimization as well as in the experimental measurements performed, which have confirmed the temperatures predicted by the model. Moreover, the experimental results and the thermodynamic database developed have been used to identify potential compositions for the MSFR fuel and to evaluate the influence of partial substitution of ThF4 by UF4 in the salt.

14 CFR 417.231 - Collision avoidance analysis.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Collision avoidance analysis. 417.231..., DEPARTMENT OF TRANSPORTATION LICENSING LAUNCH SAFETY Flight Safety Analysis § 417.231 Collision avoidance analysis. (a) General. A flight safety analysis must include a collision avoidance analysis that...

Thermodynamic assessment of the LiF-NaF-BeF2-ThF4-UF4 system

NASA Astrophysics Data System (ADS)

Capelli, E.; Beneš, O.; Konings, R. J. M.

2014-06-01

The present study describes the full thermodynamic assessment of the LiF-NaF-BeF2-ThF4-UF4 system which is one of the key systems considered for a molten salt reactor fuel. The work is an extension of the previously assessed LiF-NaF-ThF4-UF4 system with addition of BeF2 which is characterized by very low neutron capture cross section and a relatively low melting point. To extend the database the binary BeF2-ThF4 and BeF2-UF4 systems were optimized and the novel data were used for the thermodynamic assessment of BeF2 containing ternary systems for which experimental data exist in the literature. The obtained database is used to optimize the molten salt reactor fuel composition and to assess its properties with the emphasis on the melting behaviour.

7 CFR 764.231 - Conservation loan uses.

Code of Federal Regulations, 2012 CFR

2012-01-01

... not limited to: (1) The installation of conservation structures to address soil, water, and related... shelter belt purposes; (3) The installation of water conservation measures; (4) The installation of waste... 7 Agriculture 7 2012-01-01 2012-01-01 false Conservation loan uses. 764.231 Section 764.231...

49 CFR 231.4 - Fixed-end low-side gondola and low-side hopper cars.

Code of Federal Regulations, 2012 CFR

2012-10-01

...) Dimensions. Same as specified for “Box and other house cars” (see § 231.1(i)(2)). (3) Location. (i) One near... are low-side cars.) (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2) Dimensions. Same as specified for “Box and other house cars” (see § 231.1(a)(2)). (3...

49 CFR 231.4 - Fixed-end low-side gondola and low-side hopper cars.

Code of Federal Regulations, 2010 CFR

2010-10-01

...) Dimensions. Same as specified for “Box and other house cars” (see § 231.1(i)(2)). (3) Location. (i) One near... are low-side cars.) (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2) Dimensions. Same as specified for “Box and other house cars” (see § 231.1(a)(2)). (3...

49 CFR 231.4 - Fixed-end low-side gondola and low-side hopper cars.

Code of Federal Regulations, 2011 CFR

2011-10-01

...) Dimensions. Same as specified for “Box and other house cars” (see § 231.1(i)(2)). (3) Location. (i) One near... are low-side cars.) (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2) Dimensions. Same as specified for “Box and other house cars” (see § 231.1(a)(2)). (3...

49 CFR 231.5 - Drop-end low-side gondola cars.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Drop-end low-side gondola cars. 231.5 Section 231... gondola cars. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2) Dimensions. Same as specified for “Box and other house cars” (see § 231.1(a)(2)). (3...

49 CFR 231.5 - Drop-end low-side gondola cars.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Drop-end low-side gondola cars. 231.5 Section 231... gondola cars. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2) Dimensions. Same as specified for “Box and other house cars” (see § 231.1(a)(2)). (3...

49 CFR 231.3 - Drop-end high-side gondola cars.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Drop-end high-side gondola cars. 231.3 Section 231... gondola cars. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2) Dimensions. Same as specified for “Box and other house cars” (see § 231.1(a)(2)). (3...

49 CFR 231.5 - Drop-end low-side gondola cars.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Drop-end low-side gondola cars. 231.5 Section 231... gondola cars. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2) Dimensions. Same as specified for “Box and other house cars” (see § 231.1(a)(2)). (3...

49 CFR 231.5 - Drop-end low-side gondola cars.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Drop-end low-side gondola cars. 231.5 Section 231... gondola cars. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2) Dimensions. Same as specified for “Box and other house cars” (see § 231.1(a)(2)). (3...

49 CFR 231.3 - Drop-end high-side gondola cars.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Drop-end high-side gondola cars. 231.3 Section 231... gondola cars. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2) Dimensions. Same as specified for “Box and other house cars” (see § 231.1(a)(2)). (3...

49 CFR 231.3 - Drop-end high-side gondola cars.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Drop-end high-side gondola cars. 231.3 Section 231... gondola cars. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2) Dimensions. Same as specified for “Box and other house cars” (see § 231.1(a)(2)). (3...

49 CFR 231.3 - Drop-end high-side gondola cars.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Drop-end high-side gondola cars. 231.3 Section 231... gondola cars. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2) Dimensions. Same as specified for “Box and other house cars” (see § 231.1(a)(2)). (3...

49 CFR 231.5 - Drop-end low-side gondola cars.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Drop-end low-side gondola cars. 231.5 Section 231... gondola cars. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2) Dimensions. Same as specified for “Box and other house cars” (see § 231.1(a)(2)). (3...

49 CFR 231.3 - Drop-end high-side gondola cars.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Drop-end high-side gondola cars. 231.3 Section 231... gondola cars. (a) Hand brakes—(1) Number. Same as specified for “Box and other house cars” (see § 231.1(a)(1)). (2) Dimensions. Same as specified for “Box and other house cars” (see § 231.1(a)(2)). (3...

Use of rubble from building demolition in mortars.

PubMed

Corinaldesi, V; Giuggiolini, M; Moriconi, G

2002-01-01

Because of increasing waste production and public concerns about the environment, it is desirable to recycle materials from building demolition. If suitably selected, ground, cleaned and sieved in appropriate industrial crushing plants, these materials can be profitably used in concrete. Nevertheless, the presence of masonry instead of concrete rubble is particularly detrimental to the mechanical performance and durability of recycled-aggregate concrete and the same negative effect is detectable when natural sand is replaced by fine recycled aggregate fraction. An alternative use of both masonry rubble and fine recycled material fraction could be in mortars. These could contain either recycled instead of natural sand or powder obtained by bricks crushing as partial cement substitution. In particular, attention is focused on the modification that takes place when either polypropylene or stainless steel fibers are added to these mortars. Polypropylene fibers are added in order to reduce shrinkage of mortars, stainless steel fibers for improving their flexural strength. The combined use of polypropylene fibers and fine recycled material from building demolition could allow the preparation of mortars showing good performance, in particular when coupled with bricks. Furthermore, the combined use of stainless steel fibers and mortars containing brick powder seems to be an effective way to guarantee a high flexural strength.

A large submarine sand-rubble flow on kilauea volcano, hawaii

USGS Publications Warehouse

Fornari, D.J.; Moore, J.G.; Calk, L.

1979-01-01

Papa'u seamount on the south submarine slope of Kilauea volcano is a large landslide about 19 km long, 6 km wide, and up to 1 km thick with a volume of about 39 km3. Dredge hauls, remote camera photographs, and submersible observations indicate that it is composed primarily of unconsolidated angular glassy basalt sand with scattered basalt blocks up to 1 m in size; no lava flows were seen. Sulfur contents of basalt glass from several places on the sand-rubble flow and nearby areas are low (< 240 ppm), indicating that the clastic basaltic material was all erupted on land. The Papa'u sandrubble flow was emplaced during a single flow event fed from a large near-shore bank of clastic basaltic material which in turn was formed as lava flows from the summit area of Kilauea volcano disintegrated when they entered the sea. The current eruptive output of the volcano suggests that the material in the submarine sand-rubble flow represents about 6000 years of accumulation, and that the flow event occurred several thousand years ago. ?? 1979.

Effects of vertical wall and tetrapod weights on wave overtopping in rubble mound breakwaters under irregular wave conditions

NASA Astrophysics Data System (ADS)

Park, Sang Kil; Dodaran, Asgar Ahadpour; Han, Chong Soo; Shahmirzadi, Mohammad Ebrahim Meshkati

2014-12-01

Rubble mound breakwaters protect the coastal line against severe erosion caused by wave action. This study examined the performance of different sizes and properties (i.e. height of vertical wall and tetrapod size) of rubble mound breakwaters on reducing the overtopping discharge. The physical model used in this study was derived based on an actual rubble mound in Busan Yacht Harbor. This research attempts to fill the gap in practical knowledge on the combined effect of the armor roughness and vertical wall on wave overtopping in rubble mound breakwaters. The main governing parameters used in this study were the vertical wall height, variation of the tetrapod weights, initial water level elevation, and the volume of overtopping under constant wave properties. The experimental results showed that the roughness factor differed according to the tetrapod size. Furthermore, the overtopping discharge with no vertical wall was similar to that with relatively short vertical walls ( 1 γv = 1). Therefore, the experimental results highlight the importance of the height of the vertical wall in reducing overtopping discharge. Moreover, a large tetrapod size may allow coastal engineers to choose a shorter vertical wall to save cost, while obtaining better performance.

Meridional circulation across the Antarctic Circumpolar Current serves as a double 231Pa and 230Th trap

NASA Astrophysics Data System (ADS)

Rutgers van der Loeff, Michiel; Venchiarutti, Celia; Stimac, Ingrid; van Ooijen, Jan; Huhn, Oliver; Rohardt, Gerd; Strass, Volker

2016-12-01

Upwelling of Circumpolar Deep Water in the Weddell Gyre and low scavenging rates south of the Antarctic Circumpolar Current (ACC) cause an accumulation of particle reactive nuclides in the Weddell Gyre. A ventilation/reversible scavenging model that successfully described the accumulation of 230Th in this area was tested with other particle reactive nuclides and failed to adequately describe the depth-distributions of 231Pa and 210Pb. We present here a modified model that includes a nutrient-like accumulation south of the Antarctic Polar Front in an upper meridional circulation cell, as well as transport to a deep circulation cell in the Weddell Gyre by scavenging and subsequent release at depth. The model also explains depletion of 231Pa and 230Th in Weddell Sea Bottom Water (WSBW) by ventilation of newly formed deep water on a timescale of 10 years, but this water mass is too dense to leave the Weddell Gyre. In order to quantify the processes responsible for the 231Pa- and 230Th-composition of newly formed Antarctic Bottom Water (AABW) we present a mass balance of 231Pa and 230Th in the Atlantic sector of the Southern Ocean based on new data from the GEOTRACES program. The ACC receives 6.0 ± 1.5 ×106 dpms-1 of 230Th from the Weddell Sea, similar in magnitude to the net input of 4.2 ± 3.0 ×106 dpms-1 from the north. For 231Pa, the relative contribution from the Weddell Sea is much smaller, only 0.3 ± 0.1 ×106, compared to 2.7 ± 1.4 ×106 dpms-1 from the north. Weddell Sea Deep Water (WSDW) leaving the Weddell Gyre northward to form AABW is exposed in the ACC to resuspended opal-rich sediments that act as efficient scavengers with a Th/Pa fractionation factor F ≤ 1. Hydrothermal inputs may provide additional removal with low F. Scavenging in the full meridional circulation across the opal-rich ACC thus acts as a double 231Pa and 230Th trap that preconditions newly formed AABW.

Expression of Fushi tarazu factor 1 homolog and Pit-1 genes in the pituitaries of pre-spawning chum and sockeye salmon.

PubMed

Higa, M; Ando, H; Urano, A

2001-06-01

Fushi tarazu factor-1 (FTZ-F1) and Pit-1 are major pituitary transcription factors, controlling expression of genes coding for gonadotropin (GTH) subunits and growth hormone/prolactin/somatolactin family hormone, respectively. As a first step to investigate physiological factors regulating gene expression of these transcription factors, we determined their mRNA levels in the pituitaries of chum salmon (Oncorhynchus keta) at different stages of sexual maturation. FTZ-F1 gene expression was increased in males at the stage before spermiation, where the levels of GTH alpha and IIbeta subunit mRNAs were elevated. Pit-1 mRNA showed maximum levels at the final stage of sexual maturation in both sexes, when expression of somatolactin gene peaked. To clarify whether gonadotropin-releasing hormone (GnRH) is involved in these increases in FTZ-F1 and Pit-1 gene expression, we examined effects of GnRH analog (GnRHa) administration on their gene expression in maturing sockeye salmon (Oncorhynchus nerka). GnRHa stimulated Pit-1 gene expression in females only, but failed to stimulate FTZ-F1 gene expression in both sexes. The up-regulated expression of FTZ-F1 and Pit-1 genes at the pre-spawning stages suggest that the two transcription factors have roles in sexual maturation of salmonids. Physiological factors regulating gene expression of FTZ-F1 and Pit-1 are discussed in this review.

Arne - Exploring the Mare Tranquillitatis Pit

NASA Astrophysics Data System (ADS)

Robinson, M. S.; Thangavelautham, J.; Wagner, R.; Hernandez, V. A.; Finch, J.

2014-12-01

Lunar mare "pits" are key science and exploration targets. The first three pits were discovered within Selene observations [1,2] and were proposed to represent collapses into lava tubes. Subsequent LROC images revealed 5 new mare pits and showed that the Mare Tranquillitatis pit (MTP; 8.335°N, 33.222°E) opens into a sublunarean void at least 20-meters in extent [3,4]. A key remaining task is determining pit subsurface extents, and thus fully understanding their exploration and scientific value. We propose a simple and cost effective reconnaissance of the MTP using a small lander (<130 kg) named Arne, that carries three flying microbots (or pit-bots) [5,6,7]. Key measurement objectives include decimeter scale characterization of the pit walls, 5-cm scale imaging of the eastern floor, determination of the extent of sublunarean void(s), and measurement of the magnetic and thermal environment. After landing and initial surface systems check Arne will transmit full resolution descent and surface images. Within two hours the first pit-bot will launch and fly into the eastern void. Depending on results from the first pit-bot the second and third will launch and perform follow-up observations. The primary mission is expected to last 48-hours; before the Sun sets on the lander there should be enough time to execute ten flights with each pit-bot. The pit-bots are 30-cm diameter spherical flying robots [5,6,7] equipped with stereo cameras, temperature sensors, sensors for obstacle avoidance and a laser rangefinder. Lithium hydride [5,6] and water/hydrogen peroxide power three micro-thrusters and achieve a specific impulse of 350-400 s. Each pit-bot can fly for 2 min at 2 m/s for more than 100 cycles; recharge time is 20 min. Arne will carry a magnetometer, thermometer, 2 high resolution cameras, and 6 wide angle cameras and obstacle avoidance infrared sensors enabling detailed characterization of extant sublunarean voids. [1] Haruyama et al. (2010) 41st LPSC, #1285. [2

Crater Rim Layers, Rubble, and Gullies

NASA Image and Video Library

2017-08-07

This observation from NASA's Mars Reconnaissance Orbiter shows a close view of the rim and upper wall of an impact crater on the Martian surface. The layers in enhanced color are exposed subsurface strata that are relatively resistant to erosion. Boulder-like rubble beyond the crater rim is scattered down the wall of the crater (down-slope is toward the lower left of the image). Another feature of interest to Mars scientists is a large gully roughly 100 meters across. These gullies may have formed when water from melted ice on the crater walls, or from groundwater within the walls, assisted in transporting eroding material downslope. https://photojournal.jpl.nasa.gov/catalog/PIA21870

Biodiversity of Spongosorites coralliophaga (Stephens, 1915) on coral rubble at two contrasting cold-water coral reef settings

NASA Astrophysics Data System (ADS)

Kazanidis, Georgios; Henry, Lea-Anne; Roberts, J. Murray; Witte, Ursula F. M.

2016-03-01

Cold-water coral reefs (CWRs) in the northeast Atlantic harbor diverse sponge communities. Knowledge of deep-sea sponge ecology is limited and this leaves us with a fragmented understanding of the ecological roles that sponges play in CWR ecosystems. We present the first study of faunal biodiversity associated with the massive demosponge Spongosorites coralliophaga (Stephens, 1915) that typically colonizes coral debris fields of CWRs. Our study focused on the sessile fauna inhabiting sponges mixed with coral rubble at two contrasting settings in the northeast Atlantic: the shallow inshore (120-190 m water depth) Mingulay Reef Complex (MRC) and the deep offshore (500-1200 m) Logachev Mound (LM) coral province. MRC is dominated by the scleractinian Lophelia pertusa, while LM is dominated by L. pertusa and Madrepora oculata. Nine sponge-coral rubble associations were collected from MRC and four from LM. Measurements of abundance, species richness, diversity, evenness, dry biomass, and composition of sessile fauna on sponge and coral rubble microhabitats were undertaken. Differences in community composition between the two regions were mainly a response to changes in fauna with depth. Fauna composition was also different between sponge and coral rubble within each region. Infauna constituted a minor component of the sponge-associated fauna in MRC but had a higher contribution in LM. Sponge and coral rubble sessile fauna in both regions was mainly composed of cnidarians and molluscs, similarly to some previous studies. Sponges' outer surfaces at MRC were colonized by a species-rich community with high abundance and biomass suggesting that S. coralliophaga at MRC acts as a settlement surface for various organisms but such a role is not the case at LM. This difference in the role of S. coralliophaga as a biological structure is probably related to differences in fauna composition with depth, bottom current speed, and the quantity/quality of food supplied to the benthos.

NIR detection of pits and pit fragments in fresh cherries (abstract)

USDA-ARS?s Scientific Manuscript database

The feasibility of using near infrared (NIR) diffuse reflectance spectroscopy for the detection of pits and pit fragments in cherries was demonstrated. For detection of whole pits, 300 cherries were obtained locally and pits were removed from half. NIR reflectance spectra were obtained in triplicate...

Corrosion pitting of SiC by molten salts

NASA Technical Reports Server (NTRS)

Jacobson, N. S.; Smialek, J. L.

1986-01-01

The corrosion of SiC by thin films of Na2CO3 and Na2SO4 at 1000 C is characterized by a severe pitting attack of the SiC substrate. A range of different Si and SiC substrates were examined to isolate the factors critical to pitting. Two types of pitting attack are identified: attack at structural discontinuities and a crater-like attack. The crater-like pits are correlated with bubble formation during oxidation of the SiC. It appears that bubbles create unprotected regions, which are susceptible to enhanced attack and, hence, pit formation.

Dengue, related to rubble and building construction in Brazil.

PubMed

Sampaio, Angela Maria Marques; Kligerman, Débora Cynamon; Júnior, Sílvio Ferreira

2009-11-01

The fast-growing formation of solid waste, resulting from demographic density, presents itself as one of the most pressing problems to be addressed by governments of large cities all over the world. In Rio de Janeiro, 60% of solid waste stems from the construction industry. Although envisaged by under current municipal legislation, no application of policy regarding systematic recycling of this kind of waste exists in fact. Both sanitation experts and epidemiologists highlight that the deficient sanitary system contributes to the growth of endemic breeding sites, which may reach epidemic proportions. In Brazil, over the recent years, there has been an increase of Dengue Fever cases followed by deaths. In the first half of 2008, the State of Rio de Janeiro was plagued by an intense Dengue epidemic. The city of Rio de Janeiro alone accounted for 48.7% of the cases, in absolute values. By drawing upon an analytical method based on the interrelation between health and sanitation, the outcomes herein indicate that the city of Rio de Janeiro bears a direct relation between Dengue incidence rates and rubble formation from construction - measured by the total area built. Thus, there is a strong urge to implement recycling systems out of construction rubble as a sanitation measure in order to promote Dengue incidence reduction.

Initation of pitting corrosion in martensitic stainless steels. [17-4PH; 13-8Mo; Custom 450

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cieslak, W.R.; Semarge, R.E.; Bovard, F.S.

1986-01-01

The form of localized corrosion known as pitting often initiates preferentially at microstructural inhomogeneities. The pit initiation resistance, therefore, is controlled by the characteristics of the initiation sites, rather than by the bulk material composition. This investigation correlates the pit initiation resistance, as measured by critical pitting potentials, with preferred pit initiation sites for 3 martensitic stainless steels. Pit initiation sites are determined by secondary electron (SE) and backscattered electron (BSE) imaging and energy dispersive and wavelength dispersive spectrometries (EDS and WDS) with a scalling electron microscope (SEM) and an electron probe microanalyzer (EPMA).

An Autoregulatory Pathway Establishes the Definitive Chromatin Conformation at the Pit-1 Locus

PubMed Central

Cooke, Nancy E.; Liebhaber, Stephen A.

2015-01-01

The transcription factor Pit-1 (POU1-F1) plays a dominant role in cell lineage expansion and differentiation in the anterior pituitary. Prior studies of the mouse Pit-1 (mPit-1) gene revealed that this master regulatory locus is activated at embryonic day 13.5 (E13.5) by an early enhancer (EE), whereas its subsequent expression throughout adult life is maintained by a more distal definitive enhancer (DE). Here, we demonstrate that the sequential actions of these two enhancers are linked to corresponding shifts in their proximities to the Pit-1 promoter. We further demonstrate that the looping of the definitive enhancer to the mPit-1 promoter is critically dependent on a self-sustaining autoregulatory mechanism mediated by the Pit-1 protein. These Pit-1-dependent actions are accompanied by localized recruitment of CBP and enrichment for H3K27 acetylation within the Pit-1 locus. These data support a model in which the sequential actions of two developmentally activated enhancers are linked to a corresponding shift in higher-order chromatin structures. This shift establishes an autoregulatory circuit that maintains durable expression of Pit-1 throughout adult life. PMID:25691665

Meiotic and pedigree segregation analyses in carriers of t(4;8)(p16;p23.1) differing in localization of breakpoint positions at 4p subband 4p16.3 and 4p16.1.

PubMed

Midro, Alina T; Zollino, Marcella; Wiland, Ewa; Panasiuk, Barbara; Iwanowski, Piotr S; Murdolo, Marina; Śmigiel, Robert; Sąsiadek, Maria; Pilch, Jacek; Kurpisz, Maciej

2016-02-01

The purpose of this study was to compare meiotic segregation in sperm cells from two carriers with t(4;8)(p16;p23.1) reciprocal chromosome translocations (RCTs), differing in localization of the breakpoint positions at the 4p subband-namely, 4p16.3 (carrier 1) and 4p16.1 (carrier 2)-and to compare data of the pedigree analyses performed by direct method. Three-color fluorescent in situ hybridization (FISH) on sperm cells and FISH mapping for the evaluation of the breakpoint positions, data from pedigrees, and direct segregation analysis of the pedigrees were performed. Similar proportions of normal/balanced and unbalanced sperm cells were found in both carriers. The most common was an alternate type of segregation (about 52 % and about 48 %, respectively). Unbalanced adjacent I and adjacent II karyotypes were found in similar proportions about 15 %. The direct segregation analysis (following Stengel-Rutkowski) of the pedigree of carriers of t(4;8)(p16.1;p23.1) was performed and results were compared with the data of the pedigree segregation analysis obtained earlier through the indirect method. The probability of live-born progeny with unbalanced karyotype for carriers of t(4;8)(p16.1;p23.1) was moderately high at 18.8 %-comparable to the value obtained using the indirect method for the same carriership, which was 12 %. This was, however, markedly lower than the value of 41.2 % obtained through the pedigree segregation indirect analysis estimated for carriers of t(4;8)(p16.3;p23.1), perhaps due to the unique composition of genes present within the 4p16.1-4p 16.3 region. Revealed differences in pedigree segregation analysis did not correspond to the very similar profile of meiotic segregation patterns presented by carrier 1 and carrier 2. Most probably, such discordances may be due to differences in embryo survival rates arising from different genetic backgrounds.

49 CFR 231.29 - Road locomotives with corner stairways.

Code of Federal Regulations, 2011 CFR

2011-10-01

... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.29 Road locomotives with corner stairways. After September 30, 1979, road locomotives with corner stairway openings must be... 49 Transportation 4 2011-10-01 2011-10-01 false Road locomotives with corner stairways. 231.29...

49 CFR 231.29 - Road locomotives with corner stairways.

Code of Federal Regulations, 2010 CFR

2010-10-01

... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.29 Road locomotives with corner stairways. After September 30, 1979, road locomotives with corner stairway openings must be... 49 Transportation 4 2010-10-01 2010-10-01 false Road locomotives with corner stairways. 231.29...

Fabrication of spherical mitigation pit on KH2PO4 crystal by micro-milling and modeling of its induced light intensification.

PubMed

Cheng, Jian; Chen, Mingjun; Liao, Wei; Wang, Haijun; Xiao, Yong; Li, Mingquan

2013-07-15

Micro-machining is the most promising method for KH(2)PO(4) crystal to mitigate the surface damage growth in high power laser system. In this work, spherical mitigation pit is fabricated by micro-milling with an efficient machining procedure. The light intensification caused by rear surface features before and after mitigation is numerically modeled based on the finite-difference time-domain method. The results indicate that the occurrence of total internal reflections should be responsible for the largest light intensification inside the crystal. For spherical pits after mitigation, the light intensification can be greatly alleviated by preventing the occurrence of total internal reflections. The light intensification caused by spherical mitigation pit is strongly dependent on the width-depth ratio and it is suggested that the width-depth ratio of spherical mitigation pit must be devised to be larger than 5.0 to achieve the minimal light intensification for the mitigation of surface damage growth. Laser damage tests for KH(2)PO(4) crystal validate that the laser damage resistance of initially damaged surface can be retrieved to near the level of ideal surface by replacing initial damage site with predesigned mitigation pit.

Involvement of the pituitary-specific transcription factor pit-1 in somatolactotrope cell growth and death: an approach using dominant-negative pit-1 mutants.

PubMed

Pellegrini, Isabelle; Roche, Cathy; Quentien, Marie-Helene; Ferrand, Mireille; Gunz, Ginette; Thirion, Sylvie; Bagnis, Claude; Enjalbert, Alain; Franc, Jean-Louis

2006-12-01

The anterior pituitary-specific transcription factor Pit-1 was initially identified and cloned as a transactivator of the prolactin (PRL) and GH genes and later as a regulator of the TSHb gene. It was found to be a major developmental regulator, because natural Pit-1 gene mutations cause a dwarf phenotype in mice and cause combined pituitary hormone deficiency associated with pituitary hypoplasia in humans. To further investigate the growth-promoting effects of Pit-1, we used a strategy based on the use of dominant-negative Pit-1 mutants as an alternative means of inactivating endogenous Pit-1 functions. R271W, a Pit-1 mutant identified in one allele in patients with severe combined pituitary hormone deficiency, and Pit-1Delta1-123, a deletion mutant in which only the DNA binding domain of Pit-1 is conserved, were generated, and their ability to abolish the effects of the endogenous native Pit-1 in the differentiated proliferating somatolactotrope GH4C1 cell line was investigated. Enforced expression of the dominant-negative mutants in GH4C1 cells using recombinant lentiviral vectors decreased the levels of expression of known Pit-1 target genes such as PRL and GH, abolished the hormone release, and reduced cell viability by decreasing the growth rate and inducing apoptosis via a caspase-independent pathway. These results show for the first time that the growth-promoting effects of Pit-1 are at least partly due to the fact that this transcription factor prevents apoptotic cell death.

Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate.

PubMed

Zoncu, Roberto; Perera, Rushika M; Sebastian, Rafael; Nakatsu, Fubito; Chen, Hong; Balla, Tamas; Ayala, Guillermo; Toomre, Derek; De Camilli, Pietro V

2007-03-06

Phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)], a phosphoinositide concentrated predominantly in the plasma membrane, binds endocytic clathrin adaptors, many of their accessory factors, and a variety of actin-regulatory proteins. Here we have used fluorescent fusion proteins and total internal reflection fluorescence microscopy to investigate the effect of acute PI(4,5)P(2) breakdown on the dynamics of endocytic clathrin-coated pit components and of the actin regulatory complex, Arp2/3. PI(4,5)P(2) breakdown was achieved by the inducible recruitment to the plasma membrane of an inositol 5-phosphatase module through the rapamycin/FRB/FKBP system or by treatment with ionomycin. PI(4,5)P(2) depletion resulted in a dramatic loss of clathrin puncta, which correlated with a massive dissociation of endocytic adaptors from the plasma membrane. Remaining clathrin spots at the cell surface had only weak fluorescence and were static over time. Dynamin and the p20 subunit of the Arp2/3 actin regulatory complex, which were concentrated at late-stage clathrin-coated pits and in lamellipodia, also dissociated from the plasma membrane, and these changes correlated with an arrest of motility at the cell edge. These findings demonstrate the critical importance of PI(4,5)P(2) in clathrin coat dynamics and Arp2/3-dependent actin regulation.

Preliminary Study on LiF4-ThF4-PuF4 Utilization as Fuel Salt of miniFUJI Molten Salt Reactor

NASA Astrophysics Data System (ADS)

Waris, Abdul; Aji, Indarta K.; Pramuditya, Syeilendra; Widayani; Irwanto, Dwi

2016-08-01

miniFUJI reactor is molten salt reactor (MSR) which is one type of the Generation IV nuclear energy systems. The original miniFUJI reactor design uses LiF-BeF2-ThF4-233UF4 as a fuel salt. In the present study, the use of LiF4-ThF4-PuF4 as fuel salt instead of LiF-BeF2-ThF4-UF4 will be discussed. The neutronics cell calculation has been performed by using PIJ (collision probability method code) routine of SRAC 2006 code, with the nuclear data library is JENDL-4.0. The results reveal that the reactor can attain the criticality condition with the plutonium concentration in the fuel salt is equal to 9.16% or more. The conversion ratio diminishes with the enlarging of plutonium concentration in the fuel. The neutron spectrum of miniFUJI MSR with plutonium fuel becomes harder compared to that of the 233U fuel.

Familial Isolated Clubfoot Is Associated with Recurrent Chromosome 17q23.1q23.2 Microduplications Containing TBX4

PubMed Central

Alvarado, David M.; Aferol, Hyuliya; McCall, Kevin; Huang, Jason B.; Techy, Matthew; Buchan, Jillian; Cady, Janet; Gonzales, Patrick R.; Dobbs, Matthew B.; Gurnett, Christina A.

2010-01-01

Clubfoot is a common musculoskeletal birth defect for which few causative genes have been identified. To identify the genes responsible for isolated clubfoot, we screened for genomic copy-number variants with the Affymetrix Genome-wide Human SNP Array 6.0. A recurrent chromosome 17q23.1q23.2 microduplication was identified in 3 of 66 probands with familial isolated clubfoot. The chromosome 17q23.1q23.2 microduplication segregated with autosomal-dominant clubfoot in all three families but with reduced penetrance. Mild short stature was common and one female had developmental hip dysplasia. Subtle skeletal abnormalities consisted of broad and shortened metatarsals and calcanei, small distal tibial epiphyses, and thickened ischia. Several skeletal features were opposite to those described in the reciprocal chromosome 17q23.1q23.2 microdeletion syndrome associated with developmental delay and cardiac and limb abnormalities. Of note, during our study, we also identified a microdeletion at the locus in a sibling pair with isolated clubfoot. The chromosome 17q23.1q23.2 region contains the T-box transcription factor TBX4, a likely target of the bicoid-related transcription factor PITX1 previously implicated in clubfoot etiology. Our result suggests that this chromosome 17q23.1q23.2 microduplication is a relatively common cause of familial isolated clubfoot and provides strong evidence linking clubfoot etiology to abnormal early limb development. PMID:20598276

49 CFR 212.231 - Highway-rail grade crossing inspector.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Highway-rail grade crossing inspector. 212.231... § 212.231 Highway-rail grade crossing inspector. (a) The highway-rail grade crossing inspector is required, at a minimum, to be able to conduct independent inspections of all types of highway-rail grade...

49 CFR 212.231 - Highway-rail grade crossing inspector.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Highway-rail grade crossing inspector. 212.231... § 212.231 Highway-rail grade crossing inspector. (a) The highway-rail grade crossing inspector is required, at a minimum, to be able to conduct independent inspections of all types of highway-rail grade...

49 CFR 212.231 - Highway-rail grade crossing inspector.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Highway-rail grade crossing inspector. 212.231... § 212.231 Highway-rail grade crossing inspector. (a) The highway-rail grade crossing inspector is required, at a minimum, to be able to conduct independent inspections of all types of highway-rail grade...

The Pits

NASA Technical Reports Server (NTRS)

2006-01-01

8 March 2006 This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows a portion of a pit chain on the lower, northern flank of the giant martian volcano, Arsia Mons. Pits such as these commonly form as a result of collapse of surface materials into a subsurface void, possibly along a fault or into an old lava tube. The layered material, exposed near the top of several of the pits, is shedding house-sized boulders which can be seen resting on the sloping sidewalls and floors of many of the pits.

Location near: 6.7oS, 120.1oW Image width: 3 km (1.9 mi) Illumination from: lower left Season: Southern Summer

111In-BnDTPA-F3: an Auger electron-emitting radiotherapeutic agent that targets nucleolin

PubMed Central

2012-01-01

Introduction The F3 peptide (KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK), a fragment of the human high mobility group protein 2, binds nucleolin. Nucleolin is expressed in the nuclei of normal cells but is also expressed on the membrane of some cancer cells. The goal was to investigate the use of 111In-labeled F3 peptide for Auger electron-targeted radiotherapy. Methods F3 was labeled with fluorescein isothiocyanate (FITC) for confocal microscopy and conjugated to p-SCN-benzyl-diethylenetriaminepentaacetic acid (BnDTPA) for labeling with 111In to form 111In-BnDTPA-F3. MDA-MB-231-H2N (231-H2N) human breast cancer cells were exposed to 111In-BnDTPA-F3 and used in cell fractionation, γH2AX immunostaining (a marker of DNA double-strand breaks), and clonogenic assays. In vivo, biodistribution studies of 111In-BnDTPA-F3 were performed in 231-H2N xenograft-bearing mice. In tumor growth delay studies, 111In-BnDTPA-F3 (3 μg, 6 MBq/μg) was administered intravenously to 231-H2N xenograft-bearing mice once weekly for 3 weeks. Results Membrane-binding of FITC-F3 was observed in 231-H2N cells, and there was co-localization of FITC-F3 with nucleolin in the nuclei. After exposure of 231-H2N cells to 111In-BnDTPA-F3 for 2 h, 1.7% of 111In added to the medium was membrane-bound. Of the bound 111In, 15% was internalized, and of this, 37% was localized in the nucleus. Exposure of 231-H2N cells to 111In-BnDTPA-F3 (1 μM, 6 MBq/μg) resulted in a dose-dependent increase in γH2AX foci and in a significant reduction of clonogenic survival compared to untreated cells or cells exposed to unlabeled BnDTPA-F3 (46 ± 4.1%, 100 ± 1.8%, and 132 ± 7.7%, respectively). In vivo, tumor uptake of 111In-BnDTPA-F3 (3 μg, 6 MBq/μg) at 3-h post-injection was 1% of the injected dose per gram (%ID/g), and muscle uptake was 0.5%ID/g. In tumor growth delay studies, tumor growth rate was reduced 19-fold compared to untreated or unlabeled BnDTPA-F3-treated mice (p = 0.023). Conclusion 111In-BnDTPA-F3 is

111In-BnDTPA-F3: an Auger electron-emitting radiotherapeutic agent that targets nucleolin.

PubMed

Cornelissen, Bart; Waller, Andrew; Target, Carol; Kersemans, Veerle; Smart, Sean; Vallis, Katherine A

2012-02-20

The F3 peptide (KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK), a fragment of the human high mobility group protein 2, binds nucleolin. Nucleolin is expressed in the nuclei of normal cells but is also expressed on the membrane of some cancer cells. The goal was to investigate the use of 111In-labeled F3 peptide for Auger electron-targeted radiotherapy. F3 was labeled with fluorescein isothiocyanate (FITC) for confocal microscopy and conjugated to p-SCN-benzyl-diethylenetriaminepentaacetic acid (BnDTPA) for labeling with 111In to form 111In-BnDTPA-F3. MDA-MB-231-H2N (231-H2N) human breast cancer cells were exposed to 111In-BnDTPA-F3 and used in cell fractionation, γH2AX immunostaining (a marker of DNA double-strand breaks), and clonogenic assays. In vivo, biodistribution studies of 111In-BnDTPA-F3 were performed in 231-H2N xenograft-bearing mice. In tumor growth delay studies, 111In-BnDTPA-F3 (3 μg, 6 MBq/μg) was administered intravenously to 231-H2N xenograft-bearing mice once weekly for 3 weeks. Membrane-binding of FITC-F3 was observed in 231-H2N cells, and there was co-localization of FITC-F3 with nucleolin in the nuclei. After exposure of 231-H2N cells to 111In-BnDTPA-F3 for 2 h, 1.7% of 111In added to the medium was membrane-bound. Of the bound 111In, 15% was internalized, and of this, 37% was localized in the nucleus. Exposure of 231-H2N cells to 111In-BnDTPA-F3 (1 μM, 6 MBq/μg) resulted in a dose-dependent increase in γH2AX foci and in a significant reduction of clonogenic survival compared to untreated cells or cells exposed to unlabeled BnDTPA-F3 (46 ± 4.1%, 100 ± 1.8%, and 132 ± 7.7%, respectively). In vivo, tumor uptake of 111In-BnDTPA-F3 (3 μg, 6 MBq/μg) at 3-h post-injection was 1% of the injected dose per gram (%ID/g), and muscle uptake was 0.5%ID/g. In tumor growth delay studies, tumor growth rate was reduced 19-fold compared to untreated or unlabeled BnDTPA-F3-treated mice (p = 0.023). 111In-BnDTPA-F3 is internalized into 231-H2N cells and translocates

32 CFR 231.11 - Guidelines.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Guidelines. 231.11 Section 231.11 National... PROCEDURES GOVERNING BANKS, CREDIT UNIONS AND OTHER FINANCIAL INSTITUTIONS ON DOD INSTALLATIONS Guidelines for Application of the Privacy Act to Financial Institution Operations § 231.11 Guidelines. (a) The...

28 CFR 23.1 - Purpose.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Purpose. 23.1 Section 23.1 Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL INTELLIGENCE SYSTEMS OPERATING POLICIES § 23.1 Purpose. The purpose of this regulation is to assure that all criminal intelligence systems operating through support...

28 CFR 23.1 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Purpose. 23.1 Section 23.1 Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL INTELLIGENCE SYSTEMS OPERATING POLICIES § 23.1 Purpose. The purpose of this regulation is to assure that all criminal intelligence systems operating through support...

28 CFR 23.1 - Purpose.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Purpose. 23.1 Section 23.1 Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL INTELLIGENCE SYSTEMS OPERATING POLICIES § 23.1 Purpose. The purpose of this regulation is to assure that all criminal intelligence systems operating through support...

28 CFR 23.1 - Purpose.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Purpose. 23.1 Section 23.1 Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL INTELLIGENCE SYSTEMS OPERATING POLICIES § 23.1 Purpose. The purpose of this regulation is to assure that all criminal intelligence systems operating through support...

28 CFR 23.1 - Purpose.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Purpose. 23.1 Section 23.1 Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL INTELLIGENCE SYSTEMS OPERATING POLICIES § 23.1 Purpose. The purpose of this regulation is to assure that all criminal intelligence systems operating through support...

Pitting corrosion as a mixed system: coupled deterministic-probabilistic simulation of pit growth

NASA Astrophysics Data System (ADS)

Ibrahim, Israr B. M.; Fonna, S.; Pidaparti, R.

2018-05-01

Stochastic behavior of pitting corrosion poses a unique challenge in its computational analysis. However, it also stems from electrochemical activity causing general corrosion. In this paper, a framework for corrosion pit growth simulation based on the coupling of the Cellular Automaton (CA) and Boundary Element Methods (BEM) is presented. The framework assumes that pitting corrosion is controlled by electrochemical activity inside the pit cavity. The BEM provides the prediction of electrochemical activity given the geometrical data and polarization curves, while the CA is used to simulate the evolution of pit shapes based on electrochemical activity provided by BEM. To demonstrate the methodology, a sample case of local corrosion cells formed in pitting corrosion with varied dimensions and polarization functions is considered. Results show certain shapes tend to grow in certain types of environments. Some pit shapes appear to pose a higher risk by being potentially significant stress raisers or potentially increasing the rate of corrosion under the surface. Furthermore, these pits are comparable to commonly observed pit shapes in general corrosion environments.

48 CFR 231.703 - Requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Requirements. 231.703... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Nonprofit Organizations 231.703 Requirements. Under 10 U.S.C. 2249, the costs cited in 231.205-22(a) are...

48 CFR 231.703 - Requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Requirements. 231.703... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Nonprofit Organizations 231.703 Requirements. Under 10 U.S.C. 2249, the costs cited in 231.205-22(a) are...

48 CFR 231.703 - Requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Requirements. 231.703... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Nonprofit Organizations 231.703 Requirements. Under 10 U.S.C. 2249, the costs cited in 231.205-22(a) are...

48 CFR 231.703 - Requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Requirements. 231.703... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Nonprofit Organizations 231.703 Requirements. Under 10 U.S.C. 2249, the costs cited in 231.205-22(a) are...

Is Playing in the Pit Really the Pits?: Pain, Strength, Music Performance Anxiety, and Workplace Satisfaction in Professional Musicians in Stage, Pit, and Combined Stage/Pit Orchestras.

PubMed

Kenny, Dianna T; Driscoll, Tim; Ackermann, Bronwen J

2016-03-01

Typically, Australian orchestral musicians perform on stage, in an orchestra pit, or in a combination of both workplaces. This study explored a range of physical and mental health indicators in musicians who played in these different orchestra types to ascertain whether orchestra environment was a risk factor affecting musician wellbeing. Participants comprised 380 full-time orchestral musicians from the eight major state orchestras in Australia comprised of two dedicated pit orchestras, three stage-only symphonic orchestras, and three mixed stage/pit orchestras. Participants completed a physical assessment and a range of self-report measures assessing performance-related musculoskeletal disorders (PRMD), physical characteristics including strength and perceived exertion, and psychological health, including music performance anxiety (MPA), workplace satisfaction, and bullying. Physical characteristics and performance-related musculoskeletal profiles were similar for most factors on the detailed survey completed by orchestra members. The exceptions were that pit musicians demonstrated greater shoulder and elbow strength, while mixed-workload orchestra musicians had greater flexibility Significantly more exertion was reported by pit musicians when rehearsing and performing. Stage/pit musicians reported less physical exertion when performing in the pit compared with performing on stage. Severity of MPA was significantly greater in pit musicians than mixed orchestra musicians. Pit musicians also reported more frequent bullying and lower job satisfaction compared with stage musicians. There were few differences in the objective physical measures between musicians in the different orchestra types. However, pit musicians appear more psychologically vulnerable and less satisfied with their work than musicians from the other two orchestra types. The physical and psychological characteristics of musicians who perform in different orchestra types have not been adequately

Construction integrity assessment report (ETN-98-0005) S-Farm overground transfer (OGT) system valve pit 241-S-B to valve pit 241-S-D

DOE Office of Scientific and Technical Information (OSTI.GOV)

HICKS, D.F.

1999-08-12

The S-Farm overground transfer (OGT) line will bypass the existing line(s), between valve pits 241-S-B and 241-S-D that no longer meet system requirements. The new OGT line will provide a waste transfer pipeline between these valve pits in support of saltwell pumping activities. The length of the OGT line is approximately 180 ft from pit to pit. The primary pipe is nominal 1-in. diameter stainless steel (SST) braided Ethylene-propylene Diene Monomer (EPDM) hose. The encasement pipe is a nominal 3-in., flanged, SST pipe made up of several different length pipe spool pieces (drawing H-2-829564, sh. 1 and sh. 2). Themore » OGT line slopes from valve pit 241-S-B toward valve pit 241-S-D. At each end, the primary and encasement pipe connect to a pit entry spool piece. The pit entry spool pieces are constructed of prefabricated SST materials. These spool pieces allow for the separation of the primary and encasement pipelines after the pipes have entered the valve pits (drawing H-2-818280, sh. 2). The pit entry spool pieces also allow for leak detection of the encasement pipe at each end (drawing H-2-829564, sh. 2). The OGT encasement pipeline is supported above ground by adjustable height unistrut brackets and precast concrete bases (drawing H-2-829654, sh. 1). The pipeline is heat-traced and insulated. The heat tracing and insulation supply and retain latent heat that prevents waste solidification during transfers and provides freeze protection. The total length of the pipeline is above ground, thereby negating the need for cathodic corrosion protection. This Construction Integrity Assessment Report (CIAR) is prepared by Fluor Daniel Northwest for Numatec Hanford Corporation/Lockheed Martin Hanford Corporation, the operations contractor, and the U. S. Department of Energy, the system owner. The CIAR is intended to verify that construction was performed in accordance with the provisions of Washington Administrative Code, WAC-173-303-640 (3) (c), (e), (f) and (h).« less

Spectral response of the coral rubble, living corals, and dead corals: study case on the Spermonde Archipelago, Indonesia

NASA Astrophysics Data System (ADS)

Nurdin, Nurjannah; Komatsu, Teruhisa; Yamano, Hiroya; Arafat, Gulam; Rani, Chair; Akbar AS, M.

2012-10-01

Coral reefs play important ecological services such as providing foods, biodiversity, nutrient recycling etc. for human society. On the other hand, they are threatened by human impacts such as illegal fishing and environmental changes such as rises of sea water temperature and sea level due to global warming. Thus, it is very important to monitor dynamic spatial distributions of coral reefs and related habitats such as coral rubble, dead coral, bleached corals, seagrass, etc. Hyperspectral data, in particular, offer high potential for characterizing and mapping coral reefs because of their capability to identify individual reef components based on their detailed spectral response. We studied the optical properties by measuring in situ spectra of living corals, dead coral and coral rubble covered with algae. Study site was selected in Spermonde archipelago, South Sulawesi, Indonesia because this area is included in the highest diversity of corals in the world named as Coral Triangle, which is recognized as the global centre of marine biodiversity and a global priority for conservation. Correlation analysis and cluster analysis support that there are distinct differences in reflectance spectra among categories. Common spectral characteristic of living corals, dead corals and coral rubble covered with algae was a reflectance minimum at 674 nm. Healthy corals, dead coral covered with algae and coral rubble covered with algae showed high similarity of spectral reflectance. It is estimated that this is due to photsynthetic pigments.

40 CFR 231.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Definitions. 231.2 Section 231.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.2 Definitions. For the purposes of this part, the definitions of terms in 40 CFR 230.2 shall apply...

40 CFR 231.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Definitions. 231.2 Section 231.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.2 Definitions. For the purposes of this part, the definitions of terms in 40 CFR 230.2 shall apply...

22 CFR 231.15 - Notice.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Notice. 231.15 Section 231.15 Foreign Relations... WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS § 231.15 Notice. Any communication to USAID pursuant to this Guarantee shall be in writing in the English language...

49 CFR 231.22 - Operation of track motor cars.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Operation of track motor cars. 231.22 Section 231... motor cars. On and after August 1, 1963, it shall be unlawful for any railroad subject to the requirements of the Safety Appliance Acts to operate or permit to be operated on its line track motor cars to...

49 CFR 231.22 - Operation of track motor cars.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Operation of track motor cars. 231.22 Section 231... motor cars. On and after August 1, 1963, it shall be unlawful for any railroad subject to the requirements of the Safety Appliance Acts to operate or permit to be operated on its line track motor cars to...

49 CFR 231.22 - Operation of track motor cars.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Operation of track motor cars. 231.22 Section 231... motor cars. On and after August 1, 1963, it shall be unlawful for any railroad subject to the requirements of the Safety Appliance Acts to operate or permit to be operated on its line track motor cars to...

49 CFR 231.22 - Operation of track motor cars.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Operation of track motor cars. 231.22 Section 231... motor cars. On and after August 1, 1963, it shall be unlawful for any railroad subject to the requirements of the Safety Appliance Acts to operate or permit to be operated on its line track motor cars to...

49 CFR 231.22 - Operation of track motor cars.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Operation of track motor cars. 231.22 Section 231... motor cars. On and after August 1, 1963, it shall be unlawful for any railroad subject to the requirements of the Safety Appliance Acts to operate or permit to be operated on its line track motor cars to...

Familial isolated clubfoot is associated with recurrent chromosome 17q23.1q23.2 microduplications containing TBX4.

PubMed

Alvarado, David M; Aferol, Hyuliya; McCall, Kevin; Huang, Jason B; Techy, Matthew; Buchan, Jillian; Cady, Janet; Gonzales, Patrick R; Dobbs, Matthew B; Gurnett, Christina A

2010-07-09

Clubfoot is a common musculoskeletal birth defect for which few causative genes have been identified. To identify the genes responsible for isolated clubfoot, we screened for genomic copy-number variants with the Affymetrix Genome-wide Human SNP Array 6.0. A recurrent chromosome 17q23.1q23.2 microduplication was identified in 3 of 66 probands with familial isolated clubfoot. The chromosome 17q23.1q23.2 microduplication segregated with autosomal-dominant clubfoot in all three families but with reduced penetrance. Mild short stature was common and one female had developmental hip dysplasia. Subtle skeletal abnormalities consisted of broad and shortened metatarsals and calcanei, small distal tibial epiphyses, and thickened ischia. Several skeletal features were opposite to those described in the reciprocal chromosome 17q23.1q23.2 microdeletion syndrome associated with developmental delay and cardiac and limb abnormalities. Of note, during our study, we also identified a microdeletion at the locus in a sibling pair with isolated clubfoot. The chromosome 17q23.1q23.2 region contains the T-box transcription factor TBX4, a likely target of the bicoid-related transcription factor PITX1 previously implicated in clubfoot etiology. Our result suggests that this chromosome 17q23.1q23.2 microduplication is a relatively common cause of familial isolated clubfoot and provides strong evidence linking clubfoot etiology to abnormal early limb development. Copyright 2010 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

Pluto Pits

NASA Image and Video Library

2015-11-10

NASA New Horizons cameras have spied swarms of mysterious pits across the informally named Sputnik Planum. Scientists believe the pits may form through a combination of sublimation and ice fracturing. http://photojournal.jpl.nasa.gov/catalog/PIA20151

49 CFR 231.15 - Steam locomotives used in road service.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Steam locomotives used in road service. 231.15 Section 231.15 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... in road service. (a) Tender till-steps—(1) Number. Four on tender. (2) Dimensions. (i) Bottom tread...

Evaluation of a Sensor System for Detecting Humans Trapped under Rubble: A Pilot Study

PubMed Central

Kasai, Ritaro; Cosentino, Sarah; Giacomo, Cimarelli; Mochida, Yasuaki; Yamada, Hiroya; Guarnieri, Michele; Takanishi, Atsuo

2018-01-01

Rapid localization of injured survivors by rescue teams to prevent death is a major issue. In this paper, a sensor system for human rescue including three different types of sensors, a CO2 sensor, a thermal camera, and a microphone, is proposed. The performance of this system in detecting living victims under the rubble has been tested in a high-fidelity simulated disaster area. Results show that the CO2 sensor is useful to effectively reduce the possible concerned area, while the thermal camera can confirm the correct position of the victim. Moreover, it is believed that the use of microphones in connection with other sensors would be of great benefit for the detection of casualties. In this work, an algorithm to recognize voices or suspected human noise under rubble has also been developed and tested. PMID:29534055

Nuclear structure of 231Ac

NASA Astrophysics Data System (ADS)

Boutami, R.; Borge, M. J. G.; Mach, H.; Kurcewicz, W.; Fraile, L. M.; Gulda, K.; Aas, A. J.; García-Raffi, L. M.; Løvhøiden, G.; Martínez, T.; Rubio, B.; Taín, J. L.; Tengblad, O.

2008-10-01

The low-energy structure of 231Ac has been investigated by means of γ ray spectroscopy following the β decay of 231Ra. Multipolarities of 28 transitions have been established by measuring conversion electrons with a MINI-ORANGE electron spectrometer. The decay scheme of 231Ra → 231Ac has been constructed for the first time. The Advanced Time Delayed βγγ(t) method has been used to measure the half-lives of five levels. The moderately fast B(E1) transition rates derived suggest that the octupole effects, albeit weak, are still present in this exotic nucleus.

49 CFR 231.14 - Passenger-train cars without end platforms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Passenger-train cars without end platforms. 231.14... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.14 Passenger-train cars without end platforms. (a) Handbrakes—(1) Number. Each passenger-train car shall be equipped with an...

49 CFR 231.14 - Passenger-train cars without end platforms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Passenger-train cars without end platforms. 231.14... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.14 Passenger-train cars without end platforms. (a) Handbrakes—(1) Number. Each passenger-train car shall be equipped with an...

49 CFR 231.14 - Passenger-train cars without end platforms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Passenger-train cars without end platforms. 231.14... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.14 Passenger-train cars without end platforms. (a) Handbrakes—(1) Number. Each passenger-train car shall be equipped with an...

49 CFR 231.12 - Passenger-train cars with wide vestibules.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Passenger-train cars with wide vestibules. 231.12... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.12 Passenger-train cars with wide vestibules. (a) Hand brakes—(1) Number. Each passenger-train car shall be equipped with an...

49 CFR 231.12 - Passenger-train cars with wide vestibules.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Passenger-train cars with wide vestibules. 231.12... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.12 Passenger-train cars with wide vestibules. (a) Hand brakes—(1) Number. Each passenger-train car shall be equipped with an...

49 CFR 231.12 - Passenger-train cars with wide vestibules.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Passenger-train cars with wide vestibules. 231.12... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.12 Passenger-train cars with wide vestibules. (a) Hand brakes—(1) Number. Each passenger-train car shall be equipped with an...

49 CFR 231.14 - Passenger-train cars without end platforms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Passenger-train cars without end platforms. 231.14... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.14 Passenger-train cars without end platforms. (a) Handbrakes—(1) Number. Each passenger-train car shall be equipped with an...

49 CFR 231.12 - Passenger-train cars with wide vestibules.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Passenger-train cars with wide vestibules. 231.12... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.12 Passenger-train cars with wide vestibules. (a) Hand brakes—(1) Number. Each passenger-train car shall be equipped with an...

49 CFR 231.12 - Passenger-train cars with wide vestibules.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Passenger-train cars with wide vestibules. 231.12... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.12 Passenger-train cars with wide vestibules. (a) Hand brakes—(1) Number. Each passenger-train car shall be equipped with an...

49 CFR 231.14 - Passenger-train cars without end platforms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Passenger-train cars without end platforms. 231.14... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY APPLIANCE STANDARDS § 231.14 Passenger-train cars without end platforms. (a) Handbrakes—(1) Number. Each passenger-train car shall be equipped with an...

Differentiation of F4 receptor profiles in pigs based on their mucin 4 polymorphism, responsiveness to oral F4 immunization and in vitro binding of F4 to villi.

PubMed

Nguyen, V U; Goetstouwers, T; Coddens, A; Van Poucke, M; Peelman, L; Deforce, D; Melkebeek, V; Cox, E

2013-03-15

F4(+) enterotoxigenic Escherichia coli (F4(+) ETEC) are an important cause of diarrhoea and mortality in piglets. F4(+) ETEC use their F4 fimbriae to adhere to specific receptors (F4Rs) on small intestinal brush borders, resulting in colonization of the small intestine. To prevent pigs from post-weaning diarrhoea, pigs should be vaccinated during the suckling period. Previously, we demonstrated that F4acR(+), but not F4acR(-) piglets could be orally immunized with purified F4 fimbriae resulting in a protective immunity against F4(+) ETEC infections, indicating that this immune response was F4R dependent. Recently, aminopeptidase N has been identified as a glycoprotein receptor important for this oral immune response. However, in some oral immunization experiments, a few F4acR(+) piglets did not show an antibody response upon oral immunization, suggesting additional receptors. Therefore, the binding profile of F4 to brush border membrane (glyco)proteins was determined for pigs differing in F4-specific antibody response upon oral immunization, in in vitro adhesion of F4(+)E. coli to small intestinal villi, and in Muc4 genotype. Six groups of pigs could be identified. Only two groups positive in all three assays showed two high molecular weight (MW) glycoprotein bands (>250kDa) suggesting that these high MW bands are linked to the MUC4 susceptible genotype. The fact that these bands were absent in the MUC4 resistant group which showed a positive immune response against F4 and was positive in the adhesion test confirm that at least one or perhaps more other F4Rs exist. Interestingly, two pigs that were positive in the villous adhesion assay did not show an immune response against F4 fimbriae. This suggests that a third receptor category might exist which allows the bacteria to adhere but does not allow effective immunization with soluble F4 fimbriae. Future research will be necessary to confirm or reveal the identity of these receptors. Copyright © 2012 Elsevier B

Perforated Pit Membranes in Imperforate Tracheary Elements of Some Angiosperms

PubMed Central

SANO, YUZOU; JANSEN, STEVEN

2006-01-01

• Background and Aims The structure of pit membranes in angiosperms has not been fully examined and our understanding about the structure is incomplete. Therefore, this study aims to illustrate the micromorphology of pit membranes in fibres and tracheids of woody species from various families. • Methods Specimens from ten species from ten genera and eight families were prepared using two techniques and examined by field-emission scanning electron microscopy. • Key Results Interfibre pit membranes with an average diameter of <4 µm were frequently perforated or appeared to be very porous. In contrast, pit membranes in imperforate tracheary elements with distinctly bordered pits and an average diameter of ≥4 µm were homogeneous and densely packed with microfibrils. These differences were observed consistently not only among species but also within a single species in which different types of imperforate tracheary elements were present. • Conclusions This study demonstrates that the structure of interfibre pit membranes differs among cell types and the differences are closely associated with the specialization of the fibre cells. It is suggested that perforated pit membranes between specialized fibres contribute to the dehydration of the fibre cells at or soon after maturation. PMID:16520339

Fine Mapping of 6q23.1 Identifies TULP4 as Contributing to Clefts.

PubMed

Vieira, Alexandre R; de Carvalho, Flavia M; Johnson, Lindsay; DeVos, Lauren; Swailes, Alexa L; Weber, Megan L; Deeley, Kathleen

2015-03-01

Objective : The aim of this work was to fine-map the region 6q23.1, which obtained suggestive linkage signal (logarithm of the odds [LOD] score = 2.22 under a recessive model) to cleft lip with or without cleft palate (CL±P) in our previous genome-wide linkage scan to identify possible genetic variants that may contribute to CL±P. Design : We used densely spaced markers spanning the entire 6q23.1 region to test for association with CL±P in a family cohort sample. Setting : Clinical information and DNA samples were obtained from families in the Philippines at their homes or primary health care clinics. Participants : The study sample consisted of 477 subjects (224 females and 253 males), segregating isolated CL±P, from 72 living in the same area in the Philippines. Main Outcome Measure : Overtransmission of alleles to persons born with CL±P. Results : We found statistical evidence of association between a marker of TULP4 (rs651333) with CL±P (P = .00007). Conclusions : Our results further support the linkage results for the chromosome 6q region and reveal a novel candidate gene for CL±P.

Molten salt corrosion of SiC: Pitting mechanism

NASA Technical Reports Server (NTRS)

Jacobson, N. S.; Smialek, J. L.

1985-01-01

Thin films of Na2SO4 and Na2CO3 at 1000 C lead to severe pitting of sintered alpha-SiC. These pits are important as they cause a strength reduction in this material. The growth of product layers is related to pit formation for the Na2CO3 case. The early reaction stages involve repeated oxidation and dissolution to form sodium silicate. This results in severe grain boundary attack. After this a porous silica layer forms between the sodium silicate melt and the SiC. The pores in this layer appear to act as paths for the melt to reach the SiC and create larger pits.

40 CFR 231.5 - Recommended determination.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Recommended determination. 231.5 Section 231.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.5 Recommended determination. (a) The Regional Administrator or his designee...

40 CFR 231.5 - Recommended determination.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended determination. 231.5 Section 231.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.5 Recommended determination. (a) The Regional Administrator or his designee...

A probability distribution model of tooth pits for evaluating time-varying mesh stiffness of pitting gears

NASA Astrophysics Data System (ADS)

Lei, Yaguo; Liu, Zongyao; Wang, Delong; Yang, Xiao; Liu, Huan; Lin, Jing

2018-06-01

Tooth damage often causes a reduction in gear mesh stiffness. Thus time-varying mesh stiffness (TVMS) can be treated as an indication of gear health conditions. This study is devoted to investigating the mesh stiffness variations of a pair of external spur gears with tooth pitting, and proposes a new model for describing tooth pitting based on probability distribution. In the model, considering the appearance and development process of tooth pitting, we model the pitting on the surface of spur gear teeth as a series of pits with a uniform distribution in the direction of tooth width and a normal distribution in the direction of tooth height, respectively. In addition, four pitting degrees, from no pitting to severe pitting, are modeled. Finally, influences of tooth pitting on TVMS are analyzed in details and the proposed model is validated by comparing with a finite element model. The comparison results show that the proposed model is effective for the TVMS evaluations of pitting gears.

33 CFR 117.231 - Brandywine Creek.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Brandywine Creek. 117.231 Section 117.231 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Delaware § 117.231 Brandywine Creek. The draw of the...

Rubble-pile Simulations Using The Open Dynamics Engine

NASA Astrophysics Data System (ADS)

Korycansky, Donald; Asphaug, E.

2008-09-01

We describe a series of calculations of low-speed collisions of km-scale rubble piles (i.e. asteroids or planetesimals), similar to previous work (Korycansky and Asphaug 2006). The rubble piles are aggregates of polyhedra held together by gravity and friction. Collision velocities are typically of order 1 to 100 m/sec.In this work we make use of a so-called "physics engine" to solve the equations of rigid-body motion and collisions of the polyhedra. Such code libraries have been primarily developed for computer simulations and games. The chief advantage of these libraries is the inclusion of sophisticated algorithms for collision detection, which we have found to be the main computational bottleneck in our calculations. The package we have used is the Open Dynamics Engine, a freely available open-source library (www.ode.org). It solves the equations of motion to first-order accuracy in time and utilizes a fast algorithm for collision detection. We have found a factor of approximately 30 speed-up for our calculations, allowing the exploration of a much larger range of parameter space and the running of multiple calculations in order to sample the stochasticity of the results. For the calculations we report on here, the basic model is the collision of an impactor in the range 0.1--1 km in diameter with a target of 1 km diameter.argets are modeled with 1000 polyhedral elements and impactors modeled with 1 to 1000 elements depending on mass. Collisions of objects with both equal-mass elements, and elements chosen from a power-law distribution, are studied. We concentrate on determining the energy required for catastrophic disruption (Q*D) as a function of impactor/target mass atio and impactor parameter for off-center collisions. This work has been supported by NASA Planetary Geology and Geophysics Program grant NNX07AQ04G.

40 CFR 231.7 - Emergency procedure.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Emergency procedure. 231.7 Section 231.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.7 Emergency procedure. Where a permit has already been issued, and the Administrator has...

40 CFR 98.231 - Reporting threshold.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Reporting threshold. 98.231 Section 98.231 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petroleum and Natural Gas Systems § 98.231 Reporting threshold. (a) You must report GHG emissions under this...

40 CFR 98.231 - Reporting threshold.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Reporting threshold. 98.231 Section 98.231 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petroleum and Natural Gas Systems § 98.231 Reporting threshold. (a) You must report GHG emissions under this...

40 CFR 98.231 - Reporting threshold.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Reporting threshold. 98.231 Section 98.231 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petroleum and Natural Gas Systems § 98.231 Reporting threshold. (a) You must report GHG emissions under this...

Tank Riser Pit Decontamination System (Pit Viper) Return on Investment and Break-Even Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Young, Joan K.; Weimar, Mark R.; Balducci, Patrick J.

2003-06-30

This study assessed the cost benefit of Pit Viper deployment for 80 tank farm pits between October 1, 2003 and September 30, 2012 under the technical baseline for applicable double-shell tank (DST) and single-shell tank (SST) projects. After this assessment had been completed, the U.S. Department of Energy (DOE) Richland Operations Office (RL) and Office of River Protection (ORP) published the Hanford Performance Management Plan (August 2003), which accelerated the schedule for SST retrieval. Then, DOE/CH2M HILL contract modification M064 (October 2002) and The Integrated Mission Acceleration Plan (March 2003) further accelerated SST retrieval and closure schedules. Twenty-six to 40more » tanks must be retrieved by 2006. Thus the schedule for SST pit entries is accelerated and the number of SST pit entries is increased. This study estimates the return on investment (ROI) and the number of pits where Pit Viper deployment would break even or save money over current manual practices. The results of the analysis indicate a positive return on the federal investment for deployment of the Pit Viper provided it is used on a sufficient number of pits.« less

22 CFR 231.16 - Governing law.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Governing law. 231.16 Section 231.16 Foreign... EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS § 231.16 Governing law. This Guarantee shall be governed by and construed in accordance with the laws of...

34 CFR 75.231 - Additional information.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 1 2014-07-01 2014-07-01 false Additional information. 75.231 Section 75.231 Education... Make A Grant § 75.231 Additional information. After selecting an application for funding, the Secretary may require the applicant to submit additional information. (Authority: 20 U.S.C. 1221e-3 and 3474) ...

Ion release and in vitro enamel fluoride uptake associated with pit and fissure sealants containing microencapsulated remineralizing agents.

PubMed

Burbank, Brant D; Cooper, Ryan L; Kava, Alyssa; Hartjes, Jennifer M; McHale, William A; Latta, Mark A; Gross, Stephen M

2017-04-01

To determine if pit-and-fissure sealants with microencapsulated remineralizing agents with sustained release of fluoride, calcium and phosphate ions could promote enamel fluoride uptake by demineralized tooth structure. Sealants that contained 5 w/w% microcapsules with aqueous solutions of 5M Ca(NO3)2 or 0.8M NaF or 6.0M K2HPO4 or a mixture of all three were prepared. Ion release profiles were measured as a function of time. Enamel fluoride uptake by demineralized tooth structure was determined. Sustained release of fluoride, calcium and phosphate ions from a sealant was demonstrated. Fluoride uptake by demineralized enamel was significantly increased compared to a control sealant manufactured without microcapsules (P< 0.01). Bovine enamel that contained 2.2±2.1 µg F/g of enamel prior to exposure to a sealant without microcapsules had 2.3±0.5 after 90 days. Enamel exposed to sealant with 5w/% NaF microcapsules went from 3.5±3.5 µg F/g of enamel prior to exposure to 148±76 after 90 days. Enamel exposed to sealant with 2 w/w% NaF, 2 w/w% Ca(NO3)2 and 1 w/w% K2HPO4 microcapsules went from 1.7±0.7 µg F/g of enamel prior to exposure to 190±137 after 90 days. Sealants with encapsulated remineralizing agents were capable of releasing biologically available fluoride, calcium, and phosphate ions. Incorporation of these microcapsules in pit and fissure sealants is a promising method for remineralization determined by enamel fluoride uptake measurements.

Regulation of endocytic recycling by C. elegans Rab35 and its regulator RME-4, a coated-pit protein

PubMed Central

Sato, Miyuki; Sato, Ken; Liou, Willisa; Pant, Saumya; Harada, Akihiro; Grant, Barth D

2008-01-01

Using Caenorhabditis elegans genetic screens, we identified receptor-mediated endocytosis (RME)-4 and RME-5/RAB-35 as important regulators of yolk endocytosis in vivo. In rme-4 and rab-35 mutants, yolk receptors do not accumulate on the plasma membrane as would be expected in an internalization mutant, rather the receptors are lost from cortical endosomes and accumulate in dispersed small vesicles, suggesting a defect in receptor recycling. Consistent with this, genetic tests indicate the RME-4 and RAB-35 function downstream of clathrin, upstream of RAB-7, and act synergistically with recycling regulators RAB-11 and RME-1. We find that RME-4 is a conserved DENN domain protein that binds to RAB-35 in its GDP-loaded conformation. GFP–RME-4 also physically interacts with AP-2, is enriched on clathrin-coated pits, and requires clathrin but not RAB-5 for cortical association. GFP–RAB-35 localizes to the plasma membrane and early endocytic compartments but is lost from endosomes in rme-4 mutants. We propose that RME-4 functions on coated pits and/or vesicles to recruit RAB-35, which in turn functions in the endosome to promote receptor recycling. PMID:18354496

[Pit-picking surgery for pilonidal disease].

PubMed

Iesalnieks, I; Deimel, S; Kienle, K; Schlitt, H J; Zülke, C

2011-10-01

The pit-picking method was first described by J. Bascom in 1980, however, this minimally invasive technique is used only by a minority of surgeons yet. Surgery was performed under local anesthesia. All primary pits in the midline were removed by excising a border of skin of <1 mm and a 1 cm long incision was made parallel to one side of the cleft to open the chronic abscess cavity. No specific postoperative wound care was given. Pit-picking surgery was carried out 157 times in a total of 153 patients (126 males) between June 2007 and November 2010. Follow-up information was available in 123 cases and 21 patients (17%) developed disease recurrence after a mean follow-up time of 7.1 months. By multivariate analysis, a body mass index (BMI) >25 kg/m(2) (p=0.019) and duration of the disease of ≥6 months (p=0.017) were statistically significantly associated with disease recurrence after pit-picking surgery. The recurrence occurred more often in male than in female patients (20% versus 4.5%, p=0.12) Patients with pilonidal disease can be successfully treated by the pit-picking procedure in more than 80% of selected cases. Female patients and non-overweight male patients with short-term disease benefit most from this treatment method.

Collapse Pits

NASA Technical Reports Server (NTRS)

2005-01-01

24 April 2005 This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows a large and several small pits formed by collapse along the trend of a fault system in the Uranius Fossae region of Mars. Running diagonal from middle-right toward lower left is a trough that intersects the pit. The trough is a typical graben formed by faulting as the upper crust of Mars split and pulled apart at this location. The opening of the graben also led to formation of the collapse pits.

Location near: 26.2oN, 88.7oW Image width: 3 km (1.9 mi) Illumination from: lower left Season: Northern Summer

Effects of RNA interference-mediated silencing of toll-like receptor 4 gene on proliferation and apoptosis of human breast cancer MCF-7 and MDA-MB-231 cells: An in vitro study.

PubMed

Gao, Xiao-Ling; Yang, Jiao-Jiao; Wang, Shu-Juan; Chen, Yan; Wang, Bei; Cheng, Er-Jing; Gong, Jian-Nan; Dong, Yan-Ting; Liu, Dai; Wang, Xiang-Li; Huang, Ya-Qiong; An, Dong-Dong

2018-06-22

Breast cancer is known as the most prevalent cancer in women worldwide, and has an undeniable negative impact on public health, both physically, and mentally. This study aims to investigate the effects of toll-like receptor 4 (TLR4) gene silencing on proliferation and apoptosis of human breast cancer cells to explore for a new theoretical basis for its treatment. TLR4 small interference RNA (siRNA) fragment recombinant plasmids were constructed, including TLR4 siRNA-1, TLR4 siRNA-2, and TLR4 siRNA-3. Human breast cancer MCF-7 and MDA-MB-231 cells were assigned into blank, negative control (NC), TLR4 siRNA-1, TLR4 siRNA-2, and TLR4 siRNA-3 groups. MCF-7 and MDA-MB-231 cell growth was detected by MTT assay. Apoptosis and cell cycle were determined by flow cytometry. Reverse transcription quantitative polymerase chain reaction (RT-qPCR) and Western blot analysis were conducted to determine the expression of TLR4, CDK4, cyclin D1, Livin, Bcl-2, p53, c-FLIP, and caspase-3. In comparison with the NC and blank groups, the TLR4 siRNA-1, TLR4 siRNA-2, and TLR4 siRNA-3 groups showed decreased the expression of TLR4, inhibited proliferation of MCF-7 and MDA-MB-231 cells and promoted MCF-7 and MDA-MB-231 cell apoptosis, and the cells were blocked in G1 phase. In comparison with the NC and blank groups, in the TLR4 siRNA-1, TLR4 siRNA-2, and TLR4 siRNA-3 groups, siRNA-TLR4 significantly increased expression of p53 and caspase-3 in MCF-7 and MDA-MB-231 cells, while it decreased the expressions of CDK4, cyclinD1, Livin, Bal-2, and c-FLIP. The study demonstrates that TLR4 gene silencing inhibits proliferation and induces apoptosis of MCF-7 and MDA-MB-231 cells. © 2018 Wiley Periodicals, Inc.

7 CFR 1209.231 - Nominations.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 10 2013-01-01 2013-01-01 false Nominations. 1209.231 Section 1209.231 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH, AND...

7 CFR 1209.231 - Nominations.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false Nominations. 1209.231 Section 1209.231 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH, AND...

7 CFR 1209.231 - Nominations.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 10 2014-01-01 2014-01-01 false Nominations. 1209.231 Section 1209.231 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH, AND...

7 CFR 1209.231 - Nominations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Nominations. 1209.231 Section 1209.231 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH, AND...

7 CFR 1209.231 - Nominations.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Nominations. 1209.231 Section 1209.231 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH, AND...

48 CFR 231.303 - Requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Requirements. 231.303... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Educational Institutions 231.303 Requirements. (1) Pursuant to section 841 of the National Defense...

48 CFR 231.303 - Requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Requirements. 231.303... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Educational Institutions 231.303 Requirements. (1) Pursuant to section 841 of the National Defense...

48 CFR 231.303 - Requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Requirements. 231.303... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Educational Institutions 231.303 Requirements. (1) Pursuant to section 841 of the National Defense...

PIT tags increase effectiveness of freshwater mussel recaptures

USGS Publications Warehouse

Kurth, J.; Loftin, C.; Zydlewski, Joseph D.; Rhymer, Judith

2007-01-01

Translocations are used increasingly to conserve populations of rare freshwater mussels. Recovery of translocated mussels is essential to accurate assessment of translocation success. We designed an experiment to evaluate the use of passive integrated transponder (PIT) tags to mark and track individual freshwater mussels. We used eastern lampmussels (Lampsilis radiata radiata) as a surrogate for 2 rare mussel species. We assessed internal and external PIT-tag retention in the laboratory and field. Internal tag retention was high (75-100%), and tag rejection occurred primarily during the first 3 wk after tagging. A thin layer of nacre coated internal tags 3 to 4 mo after insertion, suggesting that long-term retention is likely. We released mussels with external PIT tags at 3 field study sites and recaptured them with a PIT pack (mobile interrogation unit) 8 to 10 mo and 21 to 23 mo after release. Numbers of recaptured mussels differed among study sites; however, we found more tagged mussels with the PIT-pack searches with visual confirmation (72-80%) than with visual searches alone (30-47%) at all sites. PIT tags offer improved recapture of translocated mussels and increased accuracy of posttranslocation monitoring. ?? 2007 by The North American Benthological Society.

48 CFR 252.231-7000 - Supplemental cost principles.

Code of Federal Regulations, 2010 CFR

2010-10-01

... principles. 252.231-7000 Section 252.231-7000 Federal Acquisition Regulations System DEFENSE ACQUISITION... of Provisions And Clauses 252.231-7000 Supplemental cost principles. As prescribed in 231.100-70, use the following clause: Supplemental Cost Principles (DEC 1991) When the allowability of costs under...

Band of Rubble

NASA Technical Reports Server (NTRS)

2005-01-01

This artist's animation illustrates a massive asteroid belt in orbit around a star the same age and size as our Sun. Evidence for this possible belt was discovered by NASA's Spitzer Space Telescope when it spotted warm dust around the star, presumably from asteroids smashing together.

The view starts from outside the belt, where planets like the one shown here might possibly reside, then moves into to the dusty belt itself. A collision between two asteroids is depicted near the end of the movie. Collisions like this replenish the dust in the asteroid belt, making it detectable to Spitzer.

The alien belt circles a faint, nearby star called HD 69830 located 41 light-years away in the constellation Puppis. Compared to our own solar system's asteroid belt, this one is larger and closer to its star - it is 25 times as massive, and lies just inside an orbit equivalent to that of Venus. Our asteroid belt circles between the orbits of Mars and Jupiter.

Because Jupiter acts as an outer wall to our asteroid belt, shepherding its debris into a series of bands, it is possible that an unseen planet is likewise marshalling this belt's rubble. Previous observations using the radial velocity technique did not locate any large gas giant planets, indicating that any planets present in this system would have to be the size of Saturn or smaller.

Asteroids are chunks of rock from 'failed' planets, which never managed to coalesce into full-sized planets. Asteroid belts can be thought of as construction sites that accompany the building of rocky planets.

48 CFR 231.603 - Requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Requirements. 231.603... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With State, Local, and Federally Recognized Indian Tribal Governments 231.603 Requirements. Under 10 U.S.C...

48 CFR 231.603 - Requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Requirements. 231.603... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With State, Local, and Federally Recognized Indian Tribal Governments 231.603 Requirements. Under 10 U.S.C...

48 CFR 231.603 - Requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Requirements. 231.603... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With State, Local, and Federally Recognized Indian Tribal Governments 231.603 Requirements. Under 10 U.S.C...

48 CFR 231.603 - Requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Requirements. 231.603... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With State, Local, and Federally Recognized Indian Tribal Governments 231.603 Requirements. Under 10 U.S.C...

14 CFR 23.1 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Applicability. 23.1 Section 23.1 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS...) This part prescribes airworthiness standards for the issue of type certificates, and changes to those...

14 CFR 23.1 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Applicability. 23.1 Section 23.1 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS...) This part prescribes airworthiness standards for the issue of type certificates, and changes to those...

14 CFR 23.1 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Applicability. 23.1 Section 23.1 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS...) This part prescribes airworthiness standards for the issue of type certificates, and changes to those...

14 CFR 23.1 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Applicability. 23.1 Section 23.1 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS...) This part prescribes airworthiness standards for the issue of type certificates, and changes to those...

14 CFR 23.1 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Applicability. 23.1 Section 23.1 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS...) This part prescribes airworthiness standards for the issue of type certificates, and changes to those...

Central Pit Crater

NASA Image and Video Library

2015-11-13

Crater floors can have a range of features, from flat to a central peak or a central pit. This image from NASA 2001 Mars Odyssey spacecraft shows an unnamed crater in Terra Sabaea has a central pit. This unnamed crater in Terra Sabaea has a central pit. The different floor features develop do due several factors, including the size of the impactor, the geology of the surface material and the geology of the materials at depth. Orbit Number: 60737 Latitude: 22.3358 Longitude: 61.2019 Instrument: VIS Captured: 2015-08-23 20:13 http://photojournal.jpl.nasa.gov/catalog/PIA20092

40 CFR 231.6 - Administrator's final determinations.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Administrator's final determinations. 231.6 Section 231.6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.6 Administrator's final determinations. After reviewing the...

40 CFR 231.6 - Administrator's final determinations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Administrator's final determinations. 231.6 Section 231.6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.6 Administrator's final determinations. After reviewing the...

PitScan: Computer-Assisted Feature Detection

NASA Astrophysics Data System (ADS)

Wagner, R. V.; Robinson, M. S.

2018-04-01

We developed PitScan to assist in searching the very large LROC image dataset for pits — unusual <200m wide vertical-walled holes in the Moon's surface. PitScan reduces analysts' workload by pre-filtering images to identify possible pits.

Detecting Cavitation Pitting Without Disassembly

NASA Technical Reports Server (NTRS)

Barkhoudarian, S.

1986-01-01

Technique for detecting cavitation pitting in pumps, turbines, and other machinery uses low-level nuclear irradiation. Isotopes concentrated below surface emit gamma radiation, a portion of which is attenuated by overlying material. Where there are cavitation pits, output of gamma-ray detector fluctuates as detector is scanned near pits. Important to detect cavitation pits because nozzle, turbine blade, or other pump component weakened by cavitation could fail catastrophically and cause machine to explode.

Automatic Modelling of Rubble Mound Breakwaters from LIDAR Data

NASA Astrophysics Data System (ADS)

Bueno, M.; Díaz-Vilariño, L.; González-Jorge, H.; Martínez-Sánchez, J.; Arias, P.

2015-08-01

Rubble mound breakwaters maintenance is critical to the protection of beaches and ports. LiDAR systems provide accurate point clouds from the emerged part of the structure that can be modelled to make it more useful and easy to handle. This work introduces a methodology for the automatic modelling of breakwaters with armour units of cube shape. The algorithm is divided in three main steps: normal vector computation, plane segmentation, and cube reconstruction. Plane segmentation uses the normal orientation of the points and the edge length of the cube. Cube reconstruction uses the intersection of three perpendicular planes and the edge length. Three point clouds cropped from the main point cloud of the structure are used for the tests. The number of cubes detected is around 56 % for two of the point clouds and 32 % for the third one over the total physical cubes. Accuracy assessment is done by comparison with manually drawn cubes calculating the differences between the vertexes. It ranges between 6.4 cm and 15 cm. Computing time ranges between 578.5 s and 8018.2 s. The computing time increases with the number of cubes and the requirements of collision detection.

Pit-1 inhibits BRCA1 and sensitizes human breast tumors to cisplatin and vitamin D treatment

PubMed Central

Seoane, Samuel; Arias, Efigenia; Sigueiro, Rita; Sendon-Lago, Juan; Martinez-Ordoñez, Anxo; Castelao, Esteban; Eiró, Noemí; Garcia-Caballero, Tomás; Macia, Manuel; Lopez-Lopez, Rafael; Maestro, Miguel; Vizoso, Francisco; Mouriño, Antonio; Perez-Fernandez, Roman

2015-01-01

The POU class 1 homeobox 1 (POU1F1, also known as Pit-1), pertaining to the Pit-Oct-Unc (POU) family of transcription factors, has been related to tumor growth and metastasis in breast. However, its role in response to breast cancer therapy is unknown. We found that Pit-1 down-regulated DNA-damage and repair genes, and specifically inhibited BRCA1 gene expression, sensitizing breast cancer cells to DNA-damage agents. Administration of 1α, 25-dihydroxy-3-epi-vitamin D3 (3-Epi, an endogenous low calcemic vitamin D metabolite) reduced Pit-1 expression, and synergized with cisplatin, thus, decreasing cell proliferation and apoptosis in vitro, and reducing tumor growth in vivo. In addition, fifteen primary cultures of human breast tumors showed significantly decreased proliferation when treated with 3-Epi+cisplatin, compared to cisplatin alone. This response positively correlated with Pit-1 levels. Our findings demonstrate that high levels of Pit-1 and reduced BRCA1 levels increase breast cancer cell susceptibility to 3-Epi+cisplatin therapy. PMID:25992773

22 CFR 231.14 - Arbitration.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Arbitration. 231.14 Section 231.14 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS...

22 CFR 231.14 - Arbitration.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Arbitration. 231.14 Section 231.14 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS...

22 CFR 231.14 - Arbitration.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Arbitration. 231.14 Section 231.14 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS...

22 CFR 231.14 - Arbitration.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Arbitration. 231.14 Section 231.14 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS...

22 CFR 231.14 - Arbitration.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Arbitration. 231.14 Section 231.14 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS...

40 CFR 265.231 - Air emission standards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Air emission standards. 265.231 Section 265.231 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Surface Impoundments § 265.231 Air emission standards. The owner or operator shall...

40 CFR 265.231 - Air emission standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Air emission standards. 265.231 Section 265.231 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Surface Impoundments § 265.231 Air emission standards. The owner or operator shall...

40 CFR 265.231 - Air emission standards.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Air emission standards. 265.231 Section 265.231 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Surface Impoundments § 265.231 Air emission standards. The owner or operator shall...

40 CFR 265.231 - Air emission standards.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Air emission standards. 265.231 Section 265.231 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Surface Impoundments § 265.231 Air emission standards. The owner or operator shall...

Gear Fault Detection Effectiveness as Applied to Tooth Surface Pitting Fatigue Damage

NASA Technical Reports Server (NTRS)

Lewicki, David G.; Dempsey, Paula J.; Heath, Gregory F.; Shanthakumaran, Perumal

2009-01-01

A study was performed to evaluate fault detection effectiveness as applied to gear tooth pitting fatigue damage. Vibration and oil-debris monitoring (ODM) data were gathered from 24 sets of spur pinion and face gears run during a previous endurance evaluation study. Three common condition indicators (RMS, FM4, and NA4) were deduced from the time-averaged vibration data and used with the ODM to evaluate their performance for gear fault detection. The NA4 parameter showed to be a very good condition indicator for the detection of gear tooth surface pitting failures. The FM4 and RMS parameters performed average to below average in detection of gear tooth surface pitting failures. The ODM sensor was successful in detecting a significant amount of debris from all the gear tooth pitting fatigue failures. Excluding outliers, the average cumulative mass at the end of a test was 40 mg.

NELL-1 increases pre-osteoblast mineralization using both phosphate transporter Pit1 and Pit2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cowan, Catherine M.; Dental and Craniofacial Research Institute and Section of Orthodontics, School of Dentistry, University of California, Los Angeles, 40833 Le Conte Ave, Los Angeles, CA 90095; Zhang, Xinli

2012-06-08

Highlights: Black-Right-Pointing-Pointer NELL-1 accelerates extracellular matrix mineralization in MC3T3-E1 pre-osteoblasts. Black-Right-Pointing-Pointer NELL-1 significantly increases intracellular inorganic phosphate levels. Black-Right-Pointing-Pointer NELL-1 positively regulates osteogenesis but not proliferation in MC3T3-E1 cells. Black-Right-Pointing-Pointer NELL-1 regulates inorganic phosphate transporter activity. -- Abstract: NELL-1 is a potent osteoinductive molecule that enhances bone formation in multiple animal models through currently unidentified pathways. In the present manuscript, we hypothesized that NELL-1 may regulate osteogenic differentiation accompanied by alteration of inorganic phosphate (Pi) entry into the osteoblast via sodium dependent phosphate (NaPi) transporters. To determine this, MC3T3-E1 pre-osteoblasts were cultured in the presence of recombinant human (rh)NELL-1 ormore » rhBMP-2. Analysis was performed for intracellular Pi levels through malachite green staining, Pit-1 and Pit-2 expression, and forced upregulation of Pit-1 and Pit-2. Results showed rhNELL-1 to increase MC3T3-E1 matrix mineralization and Pi influx associated with activation of both Pit-1 and Pit-2 channels, with significantly increased Pit-2 production. In contrast, Pi transport elicited by rhBMP-2 showed to be associated with increased Pit-1 production only. Next, neutralizing antibodies against Pit-1 and Pit-2 completely abrogated the Pi influx effect of rhNELL-1, suggesting rhNELL-1 is dependent on both transporters. These results identify one potential mechanism of action for rhNELL-1 induced osteogenesis and highlight a fundamental difference between NELL-1 and BMP-2 signaling.« less

13. DETAIL WEST OF TURBINE PIT SHOWING PIT DRAINED AND ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. DETAIL WEST OF TURBINE PIT SHOWING PIT DRAINED AND TURBINE EXPOSED. ORIGINAL WATER LEVEL SHOWN BY LINE JUST ABOVE ARCHED OPENING TO LEFT. WATER LINE AFTER 1982 INSTALLATION OF FLASH BOARDS REVEALED BY DARK STAIN. - Middle Creek Hydroelectric Dam, On Middle Creek, West of U.S. Route 15, 3 miles South of Selinsgrove, Selinsgrove, Snyder County, PA

32 CFR 231.2 - Policy.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Policy. 231.2 Section 231.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PROCEDURES... Policy. The policy pertaining to financial institutions operating on DoD installations is contained in Do...

Electron induced ionization of plasma processing gases: C4F x (x  =  1–8) and the isomers of C4F6 and C4F8

NASA Astrophysics Data System (ADS)

Gupta, Dhanoj; Choi, Heechol; Kwon, Deuk-Chul; Yoon, Jung-Sik; Song, Mi-Young

2018-04-01

The total ionization cross section (Q ion) for C4F x (x  =  1–8) fluorocarbons and the isomers of C4F6 and C4F8 molecules are calculated from ionization threshold to 5 keV using the binary-encounter bethe method. The targets are fully optimized using the Hartree–Fock (HF) method and density function theory (DFT) for their minimum energy structure and orbital parameters. The present Q ion with HF parameters showed good agreement with the experimental data for 1,3-C4F6, 2-C4F6, 2-C4F8 and 1-C4F8. On the other hand, the Q ion with DFT parameters are in good accordance with the recent theoretical results for 1,3-C4F6 and 2-C4F6. The Q ion for c-C4F8 showed much variation among the various results. The isomer effect in Q ion is negligible for the isomers of C4F6 and C4F8 molecules. The calculation of Q ion for C4F, C4F2, C4F3, C4F4, C4F5, c-C4F6, C4F7 and iso-C4F8 is a maiden attempt. The present cross section data are important quantities for low temperature plasma modeling especially related to the fluorocarbon plasmas.

¹¹¹In-anti-F4/80-A3-1 antibody: a novel tracer to image macrophages.

PubMed

Terry, Samantha Y A; Boerman, Otto C; Gerrits, Danny; Franssen, Gerben M; Metselaar, Josbert M; Lehmann, Steffi; Oyen, Wim J G; Gerdes, Christian A; Abiraj, Keelara

2015-08-01

Here, the expression of F4/80 on the cell surface of murine macrophages was exploited to develop a novel imaging tracer that could visualize macrophages in vivo. The immunoreactive fraction and IC50 of anti-F4/80-A3-1, conjugated with diethylenetriaminepentaacetic acid (DTPA) and radiolabelled with (111)In, were determined in vitro using murine bone marrow-derived macrophages. In vivo biodistribution studies were performed with (111)In-anti-F4/80-A3-1 and isotype-matched control antibody (111)In-rat IgG2b at 24 and 72 h post-injection (p.i.) in SCID/Beige mice bearing orthotopic MDA-MB-231 xenografts. In some studies mice were also treated with liposomal clodronate. Macrophage content in tissues was determined immunohistochemically. Micro-single photon emission computed tomography (SPECT)/CT images were also acquired. In vitro binding assays showed that (111)In-anti-F4/80-A3-1 specifically binds F4/80 receptor-positive macrophages. The immunoreactivity of anti-F4/80-A3-1 was 75 % and IC50 was 0.58 nM. In vivo, injection of 10 or 100 μg (111)In-anti-F4/80-A3-1 resulted in splenic uptake of 78 %ID/g and 31 %ID/g, respectively, and tumour uptake of 1.38 %ID/g and 4.08 %ID/g, respectively (72 h p.i.). Liposomal clodronate treatment reduced splenic uptake of 10 μg (111)In-anti-F4/80-A3-1 from 248 %ID/g to 114 %ID/g and reduced (111)In-anti-F4/80-A3-1 uptake in the liver and femur (24 h p.i.). Tracer retention in the blood and tumour uptake increased (24 h p.i.). Tumour uptake of (111)In-anti-F4/80-A3-1 was visualized by microSPECT/CT. Macrophage density in the spleen and liver decreased in mice treated with liposomal clodronate. Uptake of (111)In-rat IgG2b was lower in the spleen, liver and femur when compared to (111)In-anti-F4/80-A3-1. Radiolabelled anti-F4/80-A3-1 antibodies specifically localize in tissues infiltrated by macrophages in mice and can be used to visualize tumours. The liver and spleen act as antigen sink organs for macrophage-specific tracers.

The equilibrium of rubble-pile satellites: The Darwin and Roche ellipsoids for gravitationally held granular aggregates

NASA Astrophysics Data System (ADS)

Sharma, Ishan

2009-04-01

Many new small moons of the giant planets have been discovered recently. In parallel, satellites of several asteroids, e.g., Ida, have been found. Strikingly, a majority of these new-found planetary moons are estimated to have very low densities, which, along with their hypothesized accretionary origins, suggests a rubble internal structure. This, coupled to the fact that many asteroids are also thought to be particle aggregates held together principally by self-gravity, motivates the present investigation into the possible ellipsoidal shapes that a rubble-pile satellite may achieve as it orbits an aspherical primary. Conversely, knowledge of the shape will constrain the granular aggregate's orbit—the closer it gets to a primary, both primary's tidal effect and the satellite's spin are greater. We will assume that the primary body is sufficiently massive so as not to be influenced by the satellite. However, we will incorporate the primary's possible ellipsoidal shape, e.g., flattening at its poles in the case of a planet, and the proloidal shape of asteroids. In this, the present investigation is an extension of the first classical Darwin problem to granular aggregates. General equations defining an ellipsoidal rubble pile's equilibrium about an ellipsoidal primary are developed. They are then utilized to scrutinize the possible granular nature of small inner moons of the giant planets. It is found that most satellites satisfy constraints necessary to exist as equilibrated granular aggregates. Objects like Naiad, Metis and Adrastea appear to violate these limits, but in doing so, provide clues to their internal density and/or structure. We also recover the Roche limit for a granular satellite of a spherical primary, and employ it to study the martian satellites, Phobos and Deimos, as well as to make contact with earlier work of Davidsson [Davidsson, B., 2001. Icarus 149, 375-383]. The satellite's interior will be modeled as a rigid-plastic, cohesion-less material

7 CFR 764.231 - Conservation loan uses.

Code of Federal Regulations, 2013 CFR

2013-01-01

... timber management, erosion control, or shelter belt purposes; (3) The installation of water conservation... 7 Agriculture 7 2013-01-01 2013-01-01 false Conservation loan uses. 764.231 Section 764.231... AGRICULTURE SPECIAL PROGRAMS DIRECT LOAN MAKING Conservation Loan Program § 764.231 Conservation loan uses. (a...

7 CFR 764.231 - Conservation loan uses.

Code of Federal Regulations, 2014 CFR

2014-01-01

... timber management, erosion control, or shelter belt purposes; (3) The installation of water conservation... 7 Agriculture 7 2014-01-01 2014-01-01 false Conservation loan uses. 764.231 Section 764.231... AGRICULTURE SPECIAL PROGRAMS DIRECT LOAN MAKING Conservation Loan Program § 764.231 Conservation loan uses. (a...

Interacting Effects Induced by Two Neighboring Pits Considering Relative Position Parameters and Pit Depth

PubMed Central

Huang, Yongfang; Gang, Tieqiang; Chen, Lijie

2017-01-01

For pre-corroded aluminum alloy 7075-T6, the interacting effects of two neighboring pits on the stress concentration are comprehensively analyzed by considering various relative position parameters (inclination angle θ and dimensionless spacing parameter λ) and pit depth (d) with the finite element method. According to the severity of the stress concentration, the critical corrosion regions, bearing high susceptibility to fatigue damage, are determined for intersecting and adjacent pits, respectively. A straightforward approach is accordingly proposed to conservatively estimate the combined stress concentration factor induced by two neighboring pits, and a concrete application example is presented. It is found that for intersecting pits, the normalized stress concentration factor Ktnor increases with the increase of θ and λ and always reaches its maximum at θ = 90°, yet for adjacent pits, Ktnor decreases with the increase of λ and the maximum value appears at a slight asymmetric location. The simulations reveal that Ktnor follows a linear and an exponential relationship with the dimensionless depth parameter Rd for intersecting and adjacent cases, respectively. PMID:28772758

Atomic-scale and pit-free flattening of GaN by combination of plasma pretreatment and time-controlled chemical mechanical polishing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deng, Hui; Endo, Katsuyoshi; Yamamura, Kazuya, E-mail: yamamura@upst.eng.osaka-u.ac.jp

2015-08-03

Chemical mechanical polishing (CMP) combined with atmospheric-pressure plasma pretreatment was applied to a GaN (0001) substrate. The irradiation of a CF{sub 4}-containing plasma was proven to be very useful for modifying the surface of GaN. When CMP was conducted on a plasma-irradiated surface, a modified layer of GaF{sub 3} acted as a protective layer on GaN by preventing the formation of etch pits. Within a short duration (8 min) of CMP using a commercially available CeO{sub 2} slurry, an atomically flat surface with a root mean square (rms) roughness of 0.11 nm was obtained. Moreover, etch pits, which are inevitably introduced inmore » conventional CMP, could not be observed at the dislocation sites on the polished GaN surface. It was revealed that CMP combined with the plasma pretreatment was very effective for obtaining a pit-free and atomically flat GaN surface.« less

Pitting corrosion of titanium. The relationship between pitting potential and competitive anion adsorption at the oxide film/electrolyte interface

DOE Office of Scientific and Technical Information (OSTI.GOV)

Basame, S.B.; White, H.S.

2000-04-01

The potential-dependent breakdown of the native oxide film ({approximately}20 {angstrom} thick) on titanium has been investigated in aqueous Br{sup {minus}} solutions and in solutions that contain a mixture of Br{sup {minus}} and anions that inhibit oxide breakdown (i.e., Cl{sup {minus}}, I{sup {minus}}, SO{sub 4}{sup 2{minus}}, Fe(CN){sub 6}{sup 4{minus}}, and Fe(CN){sub 6}{sup 3{minus}}). The oxide film is unstable in neutral pH solutions containing only Br{sup {minus}}, resulting in the formation of stable corrosion pits at relatively low potentials ({approximately}1.4 V vs. Ag/AgCl). The pitting potential, E{sub p}, is strongly dependent upon the concentration of Br{sup {minus}}, and can be modeled usingmore » a Langmuir isotherm to describe the adsorption of Br{sup {minus}} at the oxide film/electrolyte interface. Addition of a second anion inhibits oxide film breakdown, as indicated by a large positive shift in E{sub p} and a decrease in the number of stable corrosion pits. The dependence of E{sub p} on the relative concentrations of Br{sup {minus}} and the inhibitor anion is consistent with competitive adsorption of the anions. Equilibrium adsorption coefficients for I{sup {minus}}, Br{sup {minus}}, and Cl{sup {minus}} are estimated from the dependence of E{sub p} on anion concentration. The results are used to establish a physical basis for the anomalously low pitting potential for titanium in aqueous Br{sup {minus}} solutions.« less

40 CFR 231.8 - Extension of time.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Extension of time. 231.8 Section 231.8 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.8 Extension of time. The Administrator or the Regional Administrator may, upon a showing of good...

40 CFR 231.8 - Extension of time.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Extension of time. 231.8 Section 231.8 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.8 Extension of time. The Administrator or the Regional Administrator may, upon a showing of good...

Gear Fault Detection Effectiveness as Applied to Tooth Surface Pitting Fatigue Damage

NASA Technical Reports Server (NTRS)

Lewicki, David G.; Dempsey, Paula J.; Heath, Gregory F.; Shanthakumaran, Perumal

2010-01-01

A study was performed to evaluate fault detection effectiveness as applied to gear-tooth-pitting-fatigue damage. Vibration and oil-debris monitoring (ODM) data were gathered from 24 sets of spur pinion and face gears run during a previous endurance evaluation study. Three common condition indicators (RMS, FM4, and NA4 [Ed. 's note: See Appendix A-Definitions D were deduced from the time-averaged vibration data and used with the ODM to evaluate their performance for gear fault detection. The NA4 parameter showed to be a very good condition indicator for the detection of gear tooth surface pitting failures. The FM4 and RMS parameters perfomu:d average to below average in detection of gear tooth surface pitting failures. The ODM sensor was successful in detecting a significant 8lDOunt of debris from all the gear tooth pitting fatigue failures. Excluding outliers, the average cumulative mass at the end of a test was 40 mg.

27 CFR 20.231 - Return.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Return. 20.231 Section 20.231 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE... shipment in accordance with § 20.171. (Approved by the Office of Management and Budget under control number...

40 CFR 231.1 - Purpose and scope.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Purpose and scope. 231.1 Section 231.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.1 Purpose and scope. (a) The Regulations of this part include the procedures to be followed by the...

40 CFR 231.1 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Purpose and scope. 231.1 Section 231.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.1 Purpose and scope. (a) The Regulations of this part include the procedures to be followed by the...

49 CFR 231.19 - Definition of “Right” and “Left.”

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Definition of âRightâ and âLeft.â 231.19 Section 231.19 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD...” and “Left.” Right or Left refers to side of person when facing end or side of car from ground. ...

49 CFR 231.19 - Definition of “Right” and “Left.”

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Definition of âRightâ and âLeft.â 231.19 Section 231.19 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD...” and “Left.” Right or Left refers to side of person when facing end or side of car from ground. ...

49 CFR 231.19 - Definition of “Right” and “Left.”

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Definition of âRightâ and âLeft.â 231.19 Section 231.19 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD...” and “Left.” Right or Left refers to side of person when facing end or side of car from ground. ...

49 CFR 231.19 - Definition of “Right” and “Left.”

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Definition of âRightâ and âLeft.â 231.19 Section 231.19 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD...” and “Left.” Right or Left refers to side of person when facing end or side of car from ground. ...

49 CFR 231.19 - Definition of “Right” and “Left.”

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Definition of âRightâ and âLeft.â 231.19 Section 231.19 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD...” and “Left.” Right or Left refers to side of person when facing end or side of car from ground. ...

7 CFR 52.779 - Freedom from pits.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false Freedom from pits. 52.779 Section 52.779 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Freedom from pits. (a) General. The factor of freedom from pits refers to the incidence of pits and pit...

Copper Causes Regiospecific Formation of C4F8-Containing Six-Membered Rings and their Defluorination/Aromatization to C4F4-Containing Rings in Triphenylene/1,4-C4F8I2 Reactions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rippy, Kerry C.; Bukovsky, Eric V.; Clikeman, Tyler T.

The presence of Cu in reactions of triphenylene (TRPH) and 1,4-C4F8I2 at 360 °C led to regiospecific substitution of TRPH ortho C(β) atoms to form C4F8-containing rings, completely suppressing substitution on C(α) atoms. In addition, Cu caused selective reductive-defluorination/aromatization (RD/A) to form C4F4- containing aromatic rings. Without Cu, the reactions of TRPH and 1,4- C4F8I2 were not regiospecific and no RD/A was observed. These results, supported by DFT calculations, are the first examples of Cupromoted (i) regiospecific perfluoroannulation, (ii) preparative C–F activation, and (iii) RD/A. HPLC-purified products were characterized by X-ray diffraction, low-temperature PES, and 1H/19F NMR.

Quantitative Correlation of 7B04 Aluminum Alloys Pitting Corrosion Morphology Characteristics with Stress Concentration Factor

NASA Astrophysics Data System (ADS)

Liu, Zhiguo; Yan, Guangyao; Mu, Zhitao; Li, Xudong

2018-01-01

The accelerated pitting corrosion test of 7B04 aluminum alloy specimen was carried out according to the spectrum which simulated airport environment, and the corresponding pitting corrosion damage was obtained and was defined through three parameters A and B and C which respectively denoted the corrosion pit surface length and width and corrosion pit depth. The ratio between three parameters could determine the morphology characteristics of corrosion pits. On this basis the stress concentration factor of typical corrosion pit morphology under certain load conditions was quantitatively analyzed. The research shows that the corrosion pits gradually incline to be ellipse in surface and moderate in depth, and most value of B/A and C/A lies in 1 between 4 and few maximum exceeds 4; The stress concentration factor Kf of corrosion pits is obviously affected by the its morphology, the value of Kf increases with corrosion pits depth increasement under certain corrosion pits surface geometry. Also, the value of Kf decreases with surface width increasement under certain corrosion pits depth. The research conclusion can set theory basis for corrosion fatigue life analysis of aircraft aluminum alloy structure.

SPERTI Reactor Pit Building (PER605) from contrasting direction as photo ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

SPERT-I Reactor Pit Building (PER-605) from contrasting direction as photo above (ID-33-F-32). Note Guard House door, security fencing around facility. Photographer: R.G. Larsen. Date: July 22, 1955. INEEL negative no. 55-1702. - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

Comet 67P's Pitted Surface

NASA Astrophysics Data System (ADS)

Kohler, Susanna

2015-11-01

High-resolution imagery of comet 67P ChuryumovGerasimenko has revealed that its surface is covered in active pits some measuring hundreds of meters both wide and deep! But what processes caused these pits to form?Pitted LandscapeESAs Rosetta mission arrived at comet 67P in August 2014. As the comet continued its journey around the Sun, Rosetta extensively documented 67Ps surface through high-resolution images taken with the on-board instrument NavCam. These images have revealed that active, circular depressions are a common feature on the comets surface.In an attempt to determine how these pits formed, an international team of scientists led by Olivier Mousis (Laboratory of Astrophysics of Marseille) has run a series of simulations of a region of the comet the Seth region that contains a 200-meter-deep pit. These simulations include the effects of various phase transitions, heat transfer through the matrix of ices and dust, and gas diffusion throughout the porous material.Escaping VolatilesAdditional examples of pitted areas on 67Ps northern-hemisphere surface include the Ash region and the Maat region (both imaged September 2014 by NavCam) [Mousis et al. 2015]Previous studies have already eliminated two potential formation mechanisms for the pits: impacts (the sizes of the pits werent right) and erosion due to sunlight (the pits dont have the right shape). Mousis and collaborators assume that the pits are instead caused by the depletion of volatile materials chemical compounds with low boiling points either via explosive outbursts at the comets surface, or via sinkholes opening from below the surface. But what process causes the volatiles to deplete when the comet heats?The authors simulations demonstrate that volatiles trapped beneath the comets surface either in icy structures called clathrates or within amorphous ice can be suddenly released as the comet warms up. The team shows that the release of volatiles from these two structures can create 200-meter

Developing a Planting Medium from Solid Waste Compost and Construction and Demolition Rubble for Use in Quarry Rehabilitation

NASA Astrophysics Data System (ADS)

Assaf, E. A.

2015-12-01

The combination of construction, demolition and excavation (CDE) waste along with the increase in solid waste generation has put a major stress on Lebanon and on the management of its solid waste. Compounding this problem are the issues of quarries closure and rehabilitation and a decrease in forest and vegetative cover. This research aims to provide an integrated solution to the stated problem by developing a "soil mix" derived from a mélange of the organic matter of the solid waste (compost), the CDE waste, and soil. Excavation and construction debris were ground to several sizes and mixed with compost and soil at different ratios. Replicates of these mixes and a set of control (regular soil) were used. In this mix, native and indicator plants are planted (in pots). The plant species used are Mathiolla crassifolia and Zea mays (Corn). Results have shown successful growth of both corn and Mathiolla seedlings in the mixes with higher amounts of construction rubble and compost i.e. Rubble: Soil: Compost Ratio of 2:1:1 and 1:0:1. However treatments with no compost and with less quantities of rubble demonstrated the inability of the soil used to sustain plant growth alone (1:1:1 and 1:1:0). Last but not least, the control consisting of soil only ended up being the weakest mix with yellow corn leaves and small Mathiolla seedlings fifty days after planting and fertilizing. Additionally, soil analysis, rubble and compost analysis were conducted. The samples were tested for heavy metals, nutrient availability and values of pH and EC. No contamination has been reported and an abundance of macronutrients and micronutrients was documented for the soil and compost. High alkalinity is due to the presence of concrete and the high percentage of Calcium Carbonate in Lebanese soils. Accordingly, the most adequate mixes for planting are treatments A (2:1:1) and B (1:0:1) and they should be pursued for a pilot scale study to test their potential use in quarry rehabilitation and

Improving Pit Vehicle Ecology Safety

NASA Astrophysics Data System (ADS)

Koptev, V. Yu; Kopteva, A. V.

2018-05-01

The article discloses the ways to improve the ecological safety of a pit transport: reducing harmful substance concentrations in exhaust gases, implementation of the ecological certificate of the dumping truck, taking into account the operation of the dumping truck actual work, choosing the best model and comparing ecological characteristics of pit lifters at deep pits.

Progressive Retinal Nerve Fiber Layer Atrophy Associated With Enlarging Peripapillary Pit.

PubMed

Lee, Eun Ji; Kim, Tae-Woo

2017-02-01

To report a case in which progressive retinal nerve fiber layer (RNFL) atrophy was observed along with enlargement of the peripapillary pit. A 34-year-old male was diagnosed with primary open-angle glaucoma and followed up for 4 years with regular ophthalmic examinations. Both eyes were myopic (-10 D, OD and -10.5 D, OS), and untreated intraocular pressures were 18 mm Hg (OD) and 16 mm Hg (OS). A subtle depression of the superotemporal peripapillary area was deepened and emerged as a peripapillary pit during the follow-up period. With the enlargement of the peripapillary pit, a RNFL defect at the location of pit widened and thinned continuously. The enlargement of the pit was documented by the spectral-domain optical coherence tomography posterior pole scanning. Progressive RNFL atrophy was observed with enlargement of the peripapillary pit. The finding suggests that tensile stress derived from the scleral stretching may have significant influence on the integrity of the RNFL.

Fourier transform emission spectroscopy of the F4Δ- X4Φ system of TiF

NASA Astrophysics Data System (ADS)

Ram, R. S.; Bernath, P. F.

2005-06-01

The emission spectra of TiF have been reinvestigated in the 4200-15 000 cm -1 region using the Fourier transform spectrometer associated with the National Solar Observatory at Kitt Peak. TiF was formed in a microwave discharge lamp operated with 2.5 Torr of He and a trace of TiF 4 vapor, and the spectra were recorded at a resolution of 0.02 cm -1. The TiF bands observed in the 12 000-14 000 cm -1 region have been assigned to a new transition, F4Δ- X4Φ. Each band consists of four sub-bands assigned as, 4Δ 1/2- 4Φ 3/2, 4Δ 3/2- 4Φ 5/2, 4Δ 5/2- 4Φ 7/2, and 4Δ 7/2- 4Φ 9/2. A rotational analysis of the 0-1, 0-0, and 1-0 bands has been obtained and spectroscopic constants have been extracted.

Ultimate open pit stochastic optimization

NASA Astrophysics Data System (ADS)

Marcotte, Denis; Caron, Josiane

2013-02-01

Classical open pit optimization (maximum closure problem) is made on block estimates, without directly considering the block grades uncertainty. We propose an alternative approach of stochastic optimization. The stochastic optimization is taken as the optimal pit computed on the block expected profits, rather than expected grades, computed from a series of conditional simulations. The stochastic optimization generates, by construction, larger ore and waste tonnages than the classical optimization. Contrary to the classical approach, the stochastic optimization is conditionally unbiased for the realized profit given the predicted profit. A series of simulated deposits with different variograms are used to compare the stochastic approach, the classical approach and the simulated approach that maximizes expected profit among simulated designs. Profits obtained with the stochastic optimization are generally larger than the classical or simulated pit. The main factor controlling the relative gain of stochastic optimization compared to classical approach and simulated pit is shown to be the information level as measured by the boreholes spacing/range ratio. The relative gains of the stochastic approach over the classical approach increase with the treatment costs but decrease with mining costs. The relative gains of the stochastic approach over the simulated pit approach increase both with the treatment and mining costs. At early stages of an open pit project, when uncertainty is large, the stochastic optimization approach appears preferable to the classical approach or the simulated pit approach for fair comparison of the values of alternative projects and for the initial design and planning of the open pit.

Limitation of the Cavitron technique by conifer pit aspiration.

PubMed

Beikircher, B; Ameglio, T; Cochard, H; Mayr, S

2010-07-01

The Cavitron technique facilitates time and material saving for vulnerability analysis. The use of rotors with small diameters leads to high water pressure gradients (DeltaP) across samples, which may cause pit aspiration in conifers. In this study, the effect of pit aspiration on Cavitron measurements was analysed and a modified 'conifer method' was tested which avoids critical (i.e. pit aspiration inducing) DeltaP. Four conifer species were used (Juniperus communis, Picea abies, Pinus sylvestris, and Larix decidua) for vulnerability analysis based on the standard Cavitron technique and the conifer method. In addition, DeltaP thresholds for pit aspiration were determined and water extraction curves were constructed. Vulnerability curves obtained with the standard method showed generally a less negative P for the induction of embolism than curves of the conifer method. Differences were species-specific with the smallest effects in Juniperus. Larix showed the most pronounced shifts in P(50) (pressure at 50% loss of conductivity) between the standard (-1.5 MPa) and the conifer (-3.5 MPa) methods. Pit aspiration occurred at the lowest DeltaP in Larix and at the highest in Juniperus. Accordingly, at a spinning velocity inducing P(50), DeltaP caused only a 4% loss of conductivity induced by pit aspiration in Juniperus, but about 60% in Larix. Water extraction curves were similar to vulnerability curves indicating that spinning itself did not affect pits. Conifer pit aspiration can have major influences on Cavitron measurements and lead to an overestimation of vulnerability thresholds when a small rotor is used. Thus, the conifer method presented here enables correct vulnerability analysis by avoiding artificial conductivity losses.

PACE4 regulates proliferation, migration and invasion in human breast cancer MDA-MB-231 cells.

PubMed

Wang, Feifei; Wang, Lin; Pan, Jihong

2015-01-01

PACE4 is one of the proprotein convertases (PC) that participate in the post-translational activation of inactive proteins, leading to mature, biologically active proteins. The processing reactions occur in pairs of basic amino acids. PACE4 is an extracellular PC that binds to growth factors and several components of the extracellular matrix contributing to tumor progression. In the present study, the PACE4 gene was silenced by small interfering RNA (siRNA), and the knockdown human breast cancer MDA-MB-231 cells showed significantly reduced proliferation, migration and invasion rates. Flow cytometry analysis indicated that downregulation of PACE4 increases the percentage of cells arrested at the G0/G1 phase. Moreover, the expression of genes involved in cell growth, invasion and adhesion, i.e., IGF-2, MMP9 and MPZL2 was significantly decreased following siRNA-mediated silencing of PACE4. Taken together, these results indicate that PACE4 plays an important role in human breast cancer, and that it might represent a novel target for breast cancer therapy.

F4+ ETEC infection and oral immunization with F4 fimbriae elicits an IL-17-dominated immune response.

PubMed

Luo, Yu; Van Nguyen, Ut; de la Fe Rodriguez, Pedro Y; Devriendt, Bert; Cox, Eric

2015-10-21

Enterotoxigenic Escherichia coli (ETEC) are an important cause of post-weaning diarrhea (PWD) in piglets. Porcine-specific ETEC strains possess different fimbrial subtypes of which F4 fimbriae are the most frequently associated with ETEC-induced diarrhea in piglets. These F4 fimbriae are potent oral immunogens that induce protective F4-specific IgA antibody secreting cells at intestinal tissues. Recently, T-helper 17 (Th17) cells have been implicated in the protection of the host against extracellular pathogens. However, it remains unknown if Th17 effector responses are needed to clear ETEC infections. In the present study, we aimed to elucidate if ETEC elicits a Th17 response in piglets and if F4 fimbriae trigger a similar response. F4(+) ETEC infection upregulated IL-17A, IL-17F, IL-21 and IL-23p19, but not IL-12 and IFN-γ mRNA expression in the systemic and mucosal immune system. Similarly, oral immunization with F4 fimbriae triggered a Th17 signature evidenced by an upregulated mRNA expression of IL-17F, RORγt, IL-23p19 and IL-21 in the peripheral blood mononuclear cells (PBMCs). Intriguingly, IL-17A mRNA levels were unaltered. To further evaluate this difference between systemic and mucosal immune responses, we assayed the cytokine mRNA profile of F4 fimbriae stimulated PBMCs. F4 fimbriae induced IL-17A, IL-17F, IL-22 and IL-23p19, but downregulated IL-17B mRNA expression. Altogether, these data indicate a Th17 dominated response upon oral immunization with F4 fimbriae and F4(+) ETEC infection. Our work also highlights that IL-17B and IL-17F participate in the immune response to protect the host against F4(+) ETEC infection and could aid in the design of future ETEC vaccines.

33 CFR 136.231 - Authorized claimants.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Authorized claimants. 136.231 Section 136.231 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

33 CFR 136.231 - Authorized claimants.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Authorized claimants. 136.231 Section 136.231 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

33 CFR 136.231 - Authorized claimants.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Authorized claimants. 136.231 Section 136.231 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

33 CFR 136.231 - Authorized claimants.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Authorized claimants. 136.231 Section 136.231 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

33 CFR 136.231 - Authorized claimants.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Authorized claimants. 136.231 Section 136.231 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

Numerical modelling of the groundwater inflow to an advancing open pit mine: Kolahdarvazeh pit, Central Iran.

PubMed

Bahrami, Saeed; Doulati Ardejani, Faramarz; Aslani, Soheyla; Baafi, Ernest

2014-12-01

The groundwater inflow into a mine during its life and after ceasing operations is one of the most important concerns of the mining industry. This paper presents a hydrogeological assessment of the Irankuh Zn-Pb mine at 20 km south of Esfahan and 1 km northeast of Abnil in west-Central Iran. During mine excavation, the upper impervious bed of a confined aquifer was broken and water at high-pressure flowed into an open pit mine associated with the Kolahdarvazeh deposit. The inflow rates were 6.7 and 1.4 m(3)/s at the maximum and minimum quantities, respectively. Permeability, storage coefficient, thickness and initial head of the fully saturated confined aquifer were 3.5 × 10(-4) m/s, 0.2, 30 m and 60 m, respectively. The hydraulic heads as a function of time were monitored at four observation wells in the vicinity of the pit over 19 weeks and at an observation well near a test well over 21 h. In addition, by measuring the rate of pumping out from the pit sump, at a constant head (usually equal to height of the pit floor), the real inflow rates to the pit were monitored. The main innovations of this work were to make comparison between numerical modelling using a finite element software called SEEP/W and actual data related to inflow and extend the applicability of the numerical model. This model was further used to estimate the hydraulic heads at the observation wells around the pit over 19 weeks during mining operations. Data from a pump-out test and observation wells were used for model calibration and verification. In order to evaluate the model efficiency, the modelling results of inflow quantity and hydraulic heads were compared to those from analytical solutions, as well as the field data. The mean percent error in relation to field data for the inflow quantity was 0.108. It varied between 1.16 and 1.46 for hydraulic head predictions, which are much lower values than the mean percent errors resulted from the analytical solutions (from 1.8 to 5

Structural stability of rubble-pile asteroids

NASA Astrophysics Data System (ADS)

Sharma, Ishan

2013-03-01

Granular aggregates, like fluids, do not admit all manners of shapes and rotation rates. It is hoped that an analysis of a suspected granular asteroid’s equilibrium shape and its structural stability will help confirm its rubble-pile nature, and, perhaps, even constrain the asteroid’s material parameters. Equilibrium shapes have been analyzed in the past by several investigators (Holsapple, K.A. [2001]. Icarus 154, 432-448; Harris, A.W., Fahnestock, E.G., Pravec, P. [2009]. Icarus 199, 310-318; Sharma, I., Jenkins, J.T., Burns, J.A. [2009]. Icarus 200, 304-322). Here, we extend the classical Lagrange-Dirichlet stability theorem to the case of self-gravitating granular aggregates. This stability test is then applied to probe the stability of several near-Earth asteroids, and explore the influence of material parameters such as internal friction angle and plastic bulk modulus. Finally, we consider their structural stability to close planetary encounters. We find that it is possible for asteroids to be stable to small perturbations, but unstable to strong and/or extended perturbations as experienced during close flybys. Conversely, assuming stability in certain situations, it is possible to estimate material properties of some asteroids like, for example, 1943 Anteros.

System for producing a uniform rubble bed for in situ processes

DOEpatents

Galloway, T.R.

1983-07-05

A method and a cutter are disclosed for producing a large cavity filled with a uniform bed of rubblized oil shale or other material, for in situ processing. A raise drill head has a hollow body with a generally circular base and sloping upper surface. A hollow shaft extends from the hollow body. Cutter teeth are mounted on the upper surface of the body and relatively small holes are formed in the body between the cutter teeth. Relatively large peripheral flutes around the body allow material to drop below the drill head. A pilot hole is drilled into the oil shale deposit. The pilot hole is reamed into a large diameter hole by means of a large diameter raise drill head or cutter to produce a cavity filled with rubble. A flushing fluid, such as air, is circulated through the pilot hole during the reaming operation to remove fines through the raise drill, thereby removing sufficient material to create sufficient void space, and allowing the larger particles to fill the cavity and provide a uniform bed of rubblized oil shale. 4 figs.

40 CFR 231.3 - Procedures for proposed determinations.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Procedures for proposed determinations. 231.3 Section 231.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.3 Procedures for proposed determinations. (a) If the Regional...

40 CFR 231.3 - Procedures for proposed determinations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Procedures for proposed determinations. 231.3 Section 231.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c) PROCEDURES § 231.3 Procedures for proposed determinations. (a) If the Regional...

High susceptibility prevalence for F4+ and F18+Escherichia coli in Flemish pigs.

PubMed

Nguyen, Ut V; Coddens, Annelies; Melkebeek, Vesna; Devriendt, Bert; Goetstouwers, Tiphanie; Poucke, Mario Van; Peelman, Luc; Cox, Eric

2017-04-01

F4 and/or F18 enterotoxigenic Escherichia coli (F4 + /F18 + ETEC) are responsible for diarrhea while F18 + verotoxigenic E. coli (F18 + VTEC) cause edema disease in pigs. Both infections can result in severe economic losses, which are mainly the result of the medication, growth retardation and mortality. The susceptibility of piglets to these pathogens is determined by the presence of F4 and F18 receptors (F4R and F18R). Understanding the composition of the susceptibility phenotypes of pigs is useful for animal health and breeding management. This study aimed to determine the prevalence of the F4 ETEC susceptibility phenotypes and F18 + E. coli susceptibility among Flemish pig breeds by using the in vitro villous adhesion assay. In this study, seven F4 ETEC susceptibility phenotypes were found, namely A (F4 ab R + , ac R + , ad R + ; 59.16%), B (F4 ab R + , ac R + , ad R - ; 6.28%), C (F4 ab R + , ac R - , ad R + ; 2.62%), D (F4 ab R - , ac R - , ad R + ; 6.28%), E (F4 ab R - , ac R - , ad R - ; 24.08%), F (F4 ab R + , ac R - , ad R - ; 1.05%) and G (F4 ab R - , ac R + , ad R - ; 0.52%). F4ab and F4ac E. coli showed a stronger degree of adhesion to the intestinal villi (53.40% and 52.88% strong adhesion, respectively), compared to F4ad E. coli (43.46% strong adhesion). Furthermore, the correlation between F4ac and F4ab adhesion was higher (r=0.78) than between F4ac and F4ad adhesion (r=0.41) and between F4ab and F4ad adhesion (r=0.57). For F18 + E. coli susceptibility, seven out of 82 pigs were F18R negative (8.54%), but only two of these seven pigs (2.44%) were also negative for F4R. As such, the chance to identify a pig that is positive for a F4 ETEC variant or F18 + E. coli is 97.56%. Therefore, significant economic losses will arise due to F4 + and/or F18 + E. coli infections in the Flemish pig population due to the high susceptibility prevalence. Copyright © 2016 Elsevier B.V. All rights reserved.

40 CFR 231.7 - Emergency procedure.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., or recreational areas, and that the public health, interest, or safety requires, the Administrator... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Emergency procedure. 231.7 Section 231.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c...

40 CFR 231.7 - Emergency procedure.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., or recreational areas, and that the public health, interest, or safety requires, the Administrator... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Emergency procedure. 231.7 Section 231.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c...

40 CFR 231.7 - Emergency procedure.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., or recreational areas, and that the public health, interest, or safety requires, the Administrator... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Emergency procedure. 231.7 Section 231.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c...

40 CFR 231.7 - Emergency procedure.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., or recreational areas, and that the public health, interest, or safety requires, the Administrator... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Emergency procedure. 231.7 Section 231.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(c...

Evaluation of the remineralization potential of amorphous calcium phosphate and fluoride containing pit and fissure sealants using scanning electron microscopy.

PubMed

Choudhary, Prashant; Tandon, Shobha; Ganesh, M; Mehra, Anshul

2012-01-01

To evaluate the remineralization potential of Amorphous Calcium Phosphate (ACP) and Fluoride containing pit and Fissure Sealants using Scanning Electron Microscopy. Thirty maxillary first premolars were divided into three groups of ten each and were randomly selected for ACP containing (Aegis- Opaque White, Bosworth Co. Ltd.), Fluoride containing (Teethmate F1 Natural Clear, Kuraray Co. Ltd.), resin based (Concise- Opaque White, 3M ESPE Co. Ltd.) pit and fissure sealant applications. The Concise group served as a control. The teeth weresubjected to the pH-cycling regimen for a period of two weeks. After two weeks, the teeth were sectioned bucco-lingually into 4mm sections and were observed under Scanning Electron Microscope at 50X, 250X, 500X, 1000X and 1500X magnifications. The qualitative changes at the tooth surface and sealant interface were examined and presence of white zone at the interface was considered positive for remineralization. Both ACP containing (Aegis) and Fluoride containing (Teethmate F1) group showed white zone at the tooth surface-sealant interface. The resin based group (Concise) showed regular interface between the sealant and the tooth structure, but no clear cut white zone was observed. Both, Aegis and Teethmate F1 have the potential to remineralize. Release of Amorphous Calcium Phosphate molecules in Aegis group and formation of Fluoroapetite in Teethmate F1 group, were probably responsible for the remineralization.

Burn Pit Emissions Exposure and Respiratory and Cardiovascular Conditions Among Airborne Hazards and Open Burn Pit Registry Participants.

PubMed

Liu, Jason; Lezama, Nicholas; Gasper, Joseph; Kawata, Jennifer; Morley, Sybil; Helmer, Drew; Ciminera, Paul

2016-07-01

The aim of this study was to determine how burn pit emissions exposure is associated with the incidence of respiratory and cardiovascular conditions. We examined the associations between assumed geographic and self-reported burn pit emissions exposure and respiratory and cardiovascular outcomes in participants of the Airborne Hazards and Open Burn Pit Registry. We found significant dose-response associations for higher risk of self-reported emphysema, chronic bronchitis, or chronic obstructive pulmonary disease with increased days of deployment within 2 miles of selected burn pits (P-trend = 0.01) and self-reported burn pit smoke exposure (P-trend = 0.0005). We found associations between burn pit emissions exposure and higher incidence of post-deployment self-reported respiratory and cardiovascular conditions, but these findings should be interpreted with caution because the surrogate measurements of burn pit emissions exposure in this analysis may not reflect individual exposure levels.

Computational fluid dynamics models of conifer bordered pits show how pit structure affects flow.

PubMed

Schulte, Paul J

2012-02-01

• The flow of xylem sap through conifer bordered pits, particularly through the pores in the pit membrane, is not well understood, but is critical for an understanding of water transport through trees. • Models solving the Navier-Stokes equation governing fluid flow were based on the geometry of bordered pits in black spruce (Picea mariana) and scanning electron microscopy images showing details of the pores in the margo of the pit membrane. • Solutions showed that the pit canals contributed a relatively small fraction of resistance to flow, whereas the torus and margo pores formed a large fraction, which depended on the structure of the individual pit. The flow through individual pores in the margo was strongly dependent on pore area, but also on the radial location of the pore with respect to the edge of the torus. • Model results suggest that only a few per cent of the pores in the margo account for nearly half of the flow and these pores tend to be located in the inner region of the margo where their contribution will be maximized. A high density of strands in outer portions of the margo (hence narrower pores) may be more significant for mechanical support of the torus. © 2011 The Author. New Phytologist © 2011 New Phytologist Trust.

22 CFR 231.03 - The Guarantee.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false The Guarantee. 231.03 Section 231.03 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS...

22 CFR 231.16 - Governing law.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Governing law. 231.16 Section 231.16 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS...

22 CFR 231.16 - Governing law.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Governing law. 231.16 Section 231.16 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS...

22 CFR 231.03 - The Guarantee.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false The Guarantee. 231.03 Section 231.03 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS...

22 CFR 231.16 - Governing law.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Governing law. 231.16 Section 231.16 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS...

22 CFR 231.03 - The Guarantee.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false The Guarantee. 231.03 Section 231.03 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS...

22 CFR 231.03 - The Guarantee.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false The Guarantee. 231.03 Section 231.03 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS...

22 CFR 231.03 - The Guarantee.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false The Guarantee. 231.03 Section 231.03 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS...

22 CFR 231.16 - Governing law.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Governing law. 231.16 Section 231.16 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND CONDITIONS...

42 CFR 2.31 - Form of written consent.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Form of written consent. 2.31 Section 2.31 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CONFIDENTIALITY OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Disclosures With Patient's Consent § 2.31 Form of written...

42 CFR 2.31 - Form of written consent.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Form of written consent. 2.31 Section 2.31 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CONFIDENTIALITY OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Disclosures With Patient's Consent § 2.31 Form of written...

42 CFR 2.31 - Form of written consent.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Form of written consent. 2.31 Section 2.31 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CONFIDENTIALITY OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Disclosures With Patient's Consent § 2.31 Form of written...

42 CFR 2.31 - Form of written consent.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Form of written consent. 2.31 Section 2.31 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CONFIDENTIALITY OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Disclosures With Patient's Consent § 2.31 Form of written...

42 CFR 2.31 - Form of written consent.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Form of written consent. 2.31 Section 2.31 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CONFIDENTIALITY OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Disclosures With Patient's Consent § 2.31 Form of written...

Sodium-dependent phosphate cotransporters and phosphate-induced calcification of vascular smooth muscle cells: Redundant roles for PiT-1 and PiT-2

PubMed Central

Crouthamel, Matthew H.; Lau, Wei Ling; Leaf, Elizabeth M.; Chavkin, Nick; Wallingford, Mary C.; Peterson, Danielle F.; Li, Xianwu; Liu, Yonggang; Chin, Michael T.; Levi, Moshe; Giachelli, Cecilia M.

2014-01-01

Objective Elevated serum phosphate has emerged as a major risk factor for vascular calcification. The sodium-dependent phosphate cotransporter, PiT-1, was previously shown to be required for phosphate-induced osteogenic differentiation and calcification of cultured human VSMCs, but its importance in vascular calcification in vivo, as well as the potential role of its homologue, PiT-2, have not been determined. We investigated the in vivo requirement for PiT-1 in vascular calcification using a mouse model of chronic kidney disease, and the potential compensatory role of PiT-2 using in vitro knockdown and over-expression strategies. Approach and Results Mice with targeted deletion of PiT-1 in VSMCs were generated (PiT-1Δsm). PiT-1 mRNA levels were undetectable whereas PiT-2 mRNA levels were increased 2 fold in the vascular aortic media of PiT-1Δsm compared to PiT-1flox/flox control. When arterial medial calcification was induced in PiT-1Δsm and PiT-1flox/flox by chronic kidney disease followed by dietary phosphate loading, the degree of aortic calcification was not different between genotypes, suggesting compensation by PiT-2. Consistent with this possibility, VSMCs isolated from PiT-1Δsm mice had no PiT-1 mRNA expression, increased PiT-2 mRNA levels, and no difference in sodium-dependent phosphate uptake or phosphate-induced matrix calcification compared to PiT-1flox/flox VSMCs. Knockdown of PiT-2 decreased phosphate uptake and phosphate-induced calcification of PiT-1Δsm VSMCs. Furthermore, over-expression of PiT-2 restored these parameters in human PiT-1-deficient VSMCs. Conclusions PiT-2 can mediate phosphate uptake and calcification of VSMCs in the absence of PiT-1. Mechanistically, PiT-1 and PiT-2 appear to serve redundant roles in phosphate-induced calcification of vascular smooth muscle cells. PMID:23968976

Structures of Bordered Pits Potentially Contributing to Isolation of a Refilled Vessel from Negative Xylem Pressure in Stems of Morus australis Poir.: Testing of the Pit Membrane Osmosis and Pit Valve Hypotheses.

PubMed

Ooeda, Hiroki; Terashima, Ichiro; Taneda, Haruhiko

2017-02-01

Two hypotheses have been proposed to explain the mechanism preventing the refilling vessel water from being drained to the neighboring functional vessels under negative pressure. The pit membrane osmosis hypothesis proposes that the xylem parenchyma cells release polysaccharides that are impermeable to the intervessel pit membranes into the refilling vessel; this osmotically counteracts the negative pressure, thereby allowing the vessel to refill. The pit valve hypothesis proposes that gas trapped within intervessel bordered pits isolates the refilling vessel water from the surrounding functional vessels. Here, using the single-vessel method, we assessed these hypotheses in shoots of mulberry (Morus australis Poir.). First, we confirmed the occurrence of xylem refilling under negative pressure in the potted mulberry saplings. To examine the pit membrane osmosis hypothesis, we estimated the semi-permeability of pit membranes for molecules of various sizes and found that the pit membranes were not semi-permeable to polyethylene glycol of molecular mass <20,000. For the pit valve hypothesis, we formed pit valves in the intervessel pits in the short stem segments and measured the maximum liquid pressure up to which gases in bordered pits were retained. The threshold pressure ranged from 0.025 to 0.10 MPa. These values matched the theoretical value calculated from the geometry of the pit chamber (0.0692-0.101 MPa). Our results suggest that gas in the pits is retained by surface tension, even under substantial positive pressure to resolve gases in the refilling vessel, whereas the molecule size required for the pit membrane osmosis mechanism in mulberry would be unrealistically large. © The Author 2016. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

7 CFR 1221.231 - Results of the referendum.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false Results of the referendum. 1221.231 Section 1221.231... INFORMATION ORDER Procedures for the Conduct of Referenda Procedures § 1221.231 Results of the referendum. (a.... The Administrator, AMS shall tabulate the results of the ballots. USDA will issue an official press...

7 CFR 1221.231 - Results of the referendum.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Results of the referendum. 1221.231 Section 1221.231... INFORMATION ORDER Procedures for the Conduct of Referenda Procedures § 1221.231 Results of the referendum. (a.... The Administrator, AMS shall tabulate the results of the ballots. USDA will issue an official press...

7 CFR 1221.231 - Results of the referendum.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 10 2014-01-01 2014-01-01 false Results of the referendum. 1221.231 Section 1221.231... INFORMATION ORDER Procedures for the Conduct of Referenda Procedures § 1221.231 Results of the referendum. (a.... The Administrator, AMS shall tabulate the results of the ballots. USDA will issue an official press...

7 CFR 1221.231 - Results of the referendum.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 10 2013-01-01 2013-01-01 false Results of the referendum. 1221.231 Section 1221.231... INFORMATION ORDER Procedures for the Conduct of Referenda Procedures § 1221.231 Results of the referendum. (a.... The Administrator, AMS shall tabulate the results of the ballots. USDA will issue an official press...

7 CFR 2.31 - General Counsel.

Code of Federal Regulations, 2014 CFR

2014-01-01

... patent applications and prosecute the same before the Patent Office. (6) Represent the Department in... 7 Agriculture 1 2014-01-01 2014-01-01 false General Counsel. 2.31 Section 2.31 Agriculture Office... legal and legislative library services to the Office of the General Counsel and the Department. (5) Make...

36 CFR 223.231 - Bidding methods.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false Bidding methods. 223.231... Forest Products Advertisement and Bids § 223.231 Bidding methods. The Contracting Officer or designated... followed by oral auction. The method selected shall: (a) Ensure open and fair competition; (b) Ensure that...

36 CFR 223.231 - Bidding methods.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Bidding methods. 223.231... Forest Products Advertisement and Bids § 223.231 Bidding methods. The Contracting Officer or designated... followed by oral auction. The method selected shall: (a) Ensure open and fair competition; (b) Ensure that...

36 CFR 223.231 - Bidding methods.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Bidding methods. 223.231... Forest Products Advertisement and Bids § 223.231 Bidding methods. The Contracting Officer or designated... followed by oral auction. The method selected shall: (a) Ensure open and fair competition; (b) Ensure that...

36 CFR 223.231 - Bidding methods.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Bidding methods. 223.231... Forest Products Advertisement and Bids § 223.231 Bidding methods. The Contracting Officer or designated... followed by oral auction. The method selected shall: (a) Ensure open and fair competition; (b) Ensure that...

12 CFR 335.231 - Certification, suspension of trading, and removal from listing by exchanges.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Certification, suspension of trading, and removal from listing by exchanges. 335.231 Section 335.231 Banks and Banking FEDERAL DEPOSIT INSURANCE... Certification, suspension of trading, and removal from listing by exchanges. The provisions of the applicable...

26 CFR 1.381(c)(23)-1 - Investment credit carryovers in certain corporate acquisitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 4 2010-04-01 2010-04-01 false Investment credit carryovers in certain corporate acquisitions. 1.381(c)(23)-1 Section 1.381(c)(23)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Insolvency Reorganizations § 1.381...

12 CFR 335.231 - Certification, suspension of trading, and removal from listing by exchanges.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Certification, suspension of trading, and removal from listing by exchanges. 335.231 Section 335.231 Banks and Banking FEDERAL DEPOSIT INSURANCE... Certification, suspension of trading, and removal from listing by exchanges. The provisions of the applicable...

CALL FOR ABSTRACTS - PIT LAKES 2004

EPA Science Inventory

This call for abstracts is for the 11/16-18/2004 Pit Lakes 2004 meeting held in Reno, NV. This conference will provide a forum for the exchange of scientific information on current domestic and international pit lake approaches, including pit lakes from arid and wet regions throu...

Comparing Results of SPH/N-body Impact Simulations Using Both Solid and Rubble-pile Target Asteroids

NASA Astrophysics Data System (ADS)

Durda, Daniel D.; Bottke, W. F.; Enke, B. L.; Nesvorný, D.; Asphaug, E.; Richardson, D. C.

2006-09-01

We have been investigating the properties of satellites and the morphology of size-frequency distributions (SFDs) resulting from a suite of 160 SPH/N-body simulations of impacts into 100-km diameter parent asteroids (Durda et al. 2004, Icarus 170, 243-257; Durda et al. 2006, Icarus, in press). These simulations have produced many valuable insights into the outcomes of cratering and disruptive impacts but were limited to monolithic basalt targets. As a natural consequence of collisional evolution, however, many asteroids have undergone a series of battering impacts that likely have left their interiors substantially fractured, if not completely rubblized. In light of this, we have re-mapped the matrix of simulations using rubble-pile target objects. We constructed the rubble-pile targets by filling the interior of the 100-km diameter spherical shell (the target envelope) with randomly sized solid spheres in mutual contact. We then assigned full damage (which reduces tensile and shear stresses to zero) to SPH particles in the contacts between the components; the remaining volume is void space. The internal spherical components have a power-law distribution of sizes simulating fragments of a pre-shattered parent object. First-look analysis of the rubble-pile results indicate some general similarities to the simulations with the monolithic targets (e.g., similar trends in the number of small, gravitationally bound satellite systems as a function of impact conditions) and some significant differences (e.g., size of largest remnants and smaller debris affecting size frequency distributions of resulting families). We will report details of a more thorough analysis and the implications for collisional models of the main asteroid belt. This work is supported by the National Science Foundation, grant number AST0407045.

27 CFR 25.231 - Finished beer.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Finished beer. 25.231... OF THE TREASURY LIQUORS BEER Beer Purchased From Another Brewer § 25.231 Finished beer. (a) A brewer may obtain beer in barrels and kegs, finished and ready for sale from another brewer. The purchasing...

27 CFR 25.231 - Finished beer.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Finished beer. 25.231... OF THE TREASURY ALCOHOL BEER Beer Purchased From Another Brewer § 25.231 Finished beer. (a) A brewer may obtain beer in barrels and kegs, finished and ready for sale from another brewer. The purchasing...

27 CFR 25.231 - Finished beer.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Finished beer. 25.231... OF THE TREASURY LIQUORS BEER Beer Purchased From Another Brewer § 25.231 Finished beer. (a) A brewer may obtain beer in barrels and kegs, finished and ready for sale from another brewer. The purchasing...

27 CFR 25.231 - Finished beer.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Finished beer. 25.231... OF THE TREASURY ALCOHOL BEER Beer Purchased From Another Brewer § 25.231 Finished beer. (a) A brewer may obtain beer in barrels and kegs, finished and ready for sale from another brewer. The purchasing...

7 CFR 4279.231 - Interest rates.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 15 2014-01-01 2014-01-01 false Interest rates. 4279.231 Section 4279.231 Agriculture... Interest rates. The provisions found in § 4279.125 apply to loans guaranteed under this subpart, except as provided in paragraphs (a) through (c) of this section. Lenders are encouraged to pass interest-rate...

27 CFR 25.231 - Finished beer.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Finished beer. 25.231... OF THE TREASURY LIQUORS BEER Beer Purchased From Another Brewer § 25.231 Finished beer. (a) A brewer may obtain beer in barrels and kegs, finished and ready for sale from another brewer. The purchasing...

7 CFR 4279.231 - Interest rates.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 15 2013-01-01 2013-01-01 false Interest rates. 4279.231 Section 4279.231 Agriculture... Interest rates. The provisions found in § 4279.125 apply to loans guaranteed under this subpart, except as provided in paragraphs (a) through (c) of this section. Lenders are encouraged to pass interest-rate...

7 CFR 4279.231 - Interest rates.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 15 2012-01-01 2012-01-01 false Interest rates. 4279.231 Section 4279.231 Agriculture... Interest rates. The provisions found in § 4279.125 apply to loans guaranteed under this subpart, except as provided in paragraphs (a) through (c) of this section. Lenders are encouraged to pass interest-rate...

PI(3,4)P2 plays critical roles in the regulation of focal adhesion dynamics of MDA-MB-231 breast cancer cells.

PubMed

Fukumoto, Miki; Ijuin, Takeshi; Takenawa, Tadaomi

2017-05-01

Phosphoinositides play pivotal roles in the regulation of cancer cell phenotypes. Among them, phosphatidylinositol 3,4-bisphosphate (PI(3,4)P 2 ) localizes to the invadopodia, and positively regulates tumor cell invasion. In this study, we examined the effect of PI(3,4)P 2 on focal adhesion dynamics in MDA-MB-231 basal breast cancer cells. Knockdown of SHIP2, a phosphatidylinositol 3,4,5-trisphosphatase (PIP 3 ) 5-phosphatase that generates PI(3,4)P 2 , in MDA-MB-231 breast cancer cells, induced the development of focal adhesions and cell spreading, leading to the suppression of invasion. In contrast, knockdown of PTEN, a 3-phosphatase that de-phosphorylates PIP 3 and PI(3,4)P 2 , induced cell shrinkage and increased cell invasion. Interestingly, additional knockdown of SHIP2 rescued these phenotypes. Overexpression of the TAPP1 PH domain, which binds to PI(3,4)P 2 , and knockdown of Lpd, a downstream effector of PI(3,4)P 2 , resulted in similar phenotypes to those induced by SHIP2 knockdown. Taken together, our results suggest that inhibition of PI(3,4)P 2 generation and/or downstream signaling could be useful for inhibiting breast cancer metastasis. © 2017 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

Parturition pit: the bony imprint of vaginal birth.

PubMed

McArthur, Tatum A; Meyer, Isuzu; Jackson, Bradford; Pitt, Michael J; Larrison, Matthew C

2016-09-01

To retrospectively evaluate for pits along the dorsum of the pubic body in females and compare the presence/absence of these pits to vaginal birth data. We retrospectively reviewed females with vaginal birth data who underwent pelvic CT. The presence of pits along the dorsum of the pubic body, pit grade (0 = not present; 1 = faintly imperceptible; 2 = present; 3 = prominent), and the presence of osteitis condensans ilii, preauricular sulcus, and sacroiliac joint vacuum phenomenon were assessed on imaging. Musculoskeletal radiologists who were blinded to the birth data evaluated the CTs. 48 males were also evaluated for the presence of pits. 482 female patients underwent CT pelvis and 171 were excluded due to lack of vaginal birth data. Of the 311 study patients, 262 had prior vaginal birth(s) and 194 had pits on CT. Only 7 of the 49 patients without prior vaginal birth had pits. There was a statistically significant association between vaginal birth and presence of pits (p < 0.0001). Patients with more prominent pits (grades 2/3) had a greater number of vaginal births. As vaginal deliveries increased, the odds of having parturition pits greatly increased, adjusting for age and race at CT (p < 0.0001). No males had pits. Our study indicates that parturition pits are associated with prior vaginal birth and should be considered a characteristic of the female pelvis. The lytic appearance of prominent pits on imaging can simulate disease and create a diagnostic dilemma for interpreting radiologists.

Parturition Pit: The Bony Imprint of Vaginal Birth

PubMed Central

Meyer, Isuzu; Jackson, Bradford; Pitt, Michael J.; Larrison, Matthew C.

2017-01-01

Purpose To retrospectively evaluate for pits along the dorsum of the pubic body in females and compare the presence/absence of these pits to vaginal birth data. Materials and Methods We retrospectively reviewed females with vaginal birth data who underwent pelvic CT. The presence of pits along the dorsum of the pubic body, pit grade (0 = not present; 1 = faintly imperceptible; 2 = present; 3 = prominent), and the presence of osteitis condensans ilii, preauricular sulcus, and sacroiliac joint vacuum phenomenon were assessed on imaging. Musculoskeletal radiologists who were blinded to the birth data evaluated the CTs. 48 males were also evaluated for the presence of pits. Results 482 female patients underwent CT pelvis and 171 were excluded due to lack of vaginal birth data. Of the 311 study patients, 262 had prior vaginal birth(s) and 194 had pits on CT. Only 7 of the 49 patients without prior vaginal birth had pits. There was a statistically significant association between vaginal birth and presence of pits (p<0.0001). Patients with more prominent pits (grades 2/3) had a greater number of vaginal births. As vaginal deliveries increased, the odds of having parturition pits greatly increased, adjusting for age and race at CT (p<0.0001). No males had pits. Conclusion Our study indicates that parturition pits are associated prior vaginal birth and should be considered a characteristic of the female pelvis. The lytic appearance of prominent pits on imaging can simulate disease and create a diagnostic dilemma for interpreting radiologists. PMID:27270921

40 CFR 98.231 - Reporting threshold.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Reporting threshold. 98.231 Section 98...) MANDATORY GREENHOUSE GAS REPORTING Petroleum and Natural Gas Systems § 98.231 Reporting threshold. (a) You... § 98.232(i) emit 25,000 metric tons of CO2 equivalent or more per year. (b) For applying the threshold...

New Generation Energy Efficient Refractory Application in Soaking Pits of Bhilai Steel Plant, Sail

NASA Astrophysics Data System (ADS)

Roy, Indranil; Chintaiah, Perumetla; Bhattacharya, Ajoy Kr.; Garai, Swapan Kr.; Ray Choudhury, Pankaj Kr.; Tiwari, Laksman

In Bhilai Steel Plant (BSP), soaking pits are used for heating ingots for successive rolling into blooms. Pits are operated at a temperature of around 1350°C. Mixed gas (Mixture of Blast Furnace gas & Coke Oven gas) of calorific value around 2040 kcal/Nm3 is used as fuel. The walls of soaking pits were lined with traditional 38% Al2O3 firebricks and top 500mm was cast with 70% Al2O3 low cement castable (LCC). This type of lining results in frequent damages due to hitting by ingots while being lifted from pit by overhead cranes thus affecting the availability of pit. Life of pits was 2 to 2.5 years in BSP with 3-4 cold repairs and 3-4 hot repairs. Energy loss through the wall is also quite high in this type of lining. To triumph over the limitations of the conventional lining, a lining design was developed for the walls which consist of special 70% Al2O3 LCC having high hot strength (HMOR) in combination with specially design flexible SS-304 anchors. Ceramic fiber blanket and insulation bricks were provided between castable and the metallic shell of the pit to minimize the heat loss. A heating schedule was developed and introduced based on available infrastructure at BSP for proper curing of modified LCC based lining. After introduction of modified lining, pit no. 14/2 is running for more than 2.5 years without any repair. To capitalize the success, two more pits i.e. 12/1 and 9/2 were converted to modified lining. These pits are also running satisfactorily for more than 1.5 years. The modification has resulted in higher availability with substantial increase in production. Shell temperature of the modified pits reduced to 90° - 140°C from 120° - 200°C of conventional pits. This shows reduction in heat loss through walls, resulting less fuel consumption and energy saving of about 18%.

49 CFR 384.231 - Satisfaction of State disqualification requirement.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 5 2010-10-01 2010-10-01 false Satisfaction of State disqualification requirement. 384.231 Section 384.231 Transportation Other Regulations Relating to Transportation (Continued... Compliance by States § 384.231 Satisfaction of State disqualification requirement. (a) Applicability. The...

Associations of polymorphisms in the Pit-1 gene with growth and carcass traits in Angus beef cattle.

PubMed

Zhao, Q; Davis, M E; Hines, H C

2004-08-01

The Pit-1 gene was studied as a candidate for genetic markers of growth and carcass traits. Angus beef cattle that were divergently selected for high- or low-blood serum IGF-I concentration were used in this study. The single-strand conformation polymorphism method was used to identify polymorphism in the Pit-1 gene including regions from intron 2 to exon 6. Two polymorphisms, Pit1I3H (HinfI) and Pit1I3NL (NlaIII), were detected in intron 3 of the Pit-1 gene. One polymorphism, Pit1I4N (BstNI), was found in intron 4, and a single nucleotide polymorphism, Pit1I5, was found in intron 5. The previously reported polymorphism in exon 6, Pit1E6H (HinfI), was also studied in 416 Angus beef cattle. Associations of the polymorphisms with growth traits, carcass traits, and IGF-I concentration were analyzed using a general linear model procedure. No significant associations were observed between these polymorphisms and growth and carcass traits.

Comparison of Ion Chemistries in Octafluoro-2-butene (2-C4F8) and in Octfluorocyclobutane (c-C4F8)

NASA Astrophysics Data System (ADS)

Jiao, Charles; Dejoseph, Charles; Garscadden, Alan

2007-10-01

2-C4F8 is one of the promising candidates to replace c-C4F8 that has been widely used for dielectric etching but is not environmentally friendly. In this study we have investigated electron impact ionization and ion-molecule reactions of 2-C4F8 using Fourier transform mass spectrometry (FTMS), and compared the results with those of c-C4F8 we have studied previously. Electron impact ionization of 2-C4F8 produces 15 ionic species including C4F7,8^+, C3F3,5,6^+, C2F4^+ and CF1-3^+ as the major ions. The total ionization cross section of 2-C4F8 reaches a maximum of 1.8x10-15 cm^2 at 90 eV. The ionization is dominated by the channel forming the parent ion C4F8^+ from 12 to 18 eV, and by the channel forming C3F5^+ from 18 to 70 eV. After 70 eV, CF3^+ becomes the dominant product ion. Among the major ions generated from the electron impact ionization of 2-C4F8, only CF^+, CF2^+ and CF3^+ are found to react with 2-C4F8, via F^- abstraction or charge transfer mechanism. The charge transfer reaction of Ar^++2-C4F8 produces primarily C4F7^+.

Morphology and Evolution of Sublimation Pits on Pluto

NASA Astrophysics Data System (ADS)

Abu-Hashmeh, N.; Conrad, J. W.; Nimmo, F.; Moore, J. M.; Stern, A.; Olkin, C.; Weaver, H. A., Jr.; Ennico Smith, K.; Young, L. A.

2017-12-01

Pluto's Sputnik Planitia region hosts a geologically young surface of nitrogen ice that exhibits striking pitted terrain (Moore et al., Science 351, 2016). These pits are most likely formed by sublimation due to incident sunlight, similar to the southern polar cap of Mars (Byrne and Ingersoll, Science 299, 2003); however, their evolution over time has resulted in unique morphological characteristics. Motivated by this, we used the high-resolution mosaic strips captured by New Horizons' Long Range Reconnaissance Imager (LORRI) to map sublimation pits in the southernmost region of Sputnik Planitia. Statistical data shows pit orientations appearing North-South dominant; their morphology also indicates extensional evolution along the major axis caused by further sublimation and contact-coalescence processes. Qualitative analysis of the region yielded indications of an evolutionary path for individual pits that coalesce into each other and exhibit an elongated end-stage. Additionally, densely-pitted regions generally appear to correlate with regions containing longer pits, implying that coalescence may be an important process for elongation. We also model the evolution geometry through competing effects of diffusion (viscous relaxation) and retreat (sublimation) (Buhler and Ingersoll, LPSC Abstract #1746, 2017). The model demonstrates single-pit and coalescing-pit evolutions that influence overall length, as well as a potential ability for the pit center to move in space while the pit morphology evolves.

Method for Identifying Lava Tubes Among Pit Craters Using Brightness Profile Across Pits on the Moon or Mars

NASA Astrophysics Data System (ADS)

Jung, Jongil; Hong, Ik-Seon; Cho, Eunjin; Yi, Yu

2016-03-01

Caves can serve as major outposts for future human exploration of the Moon and Mars. In addition, caves can protect people and electronic equipment from external hazards such as cosmic ray radiation and meteorites impacts and serve as a shelter. Numerous pit craters have been discovered on the Moon and Mars and are potential entrances to caves; the principal topographic features of pit craters are their visible internal floors and pits with vertical walls. We have devised two topographical models for investigating the relationship between the topographical characteristics and the inner void of pit craters. One of our models is a concave floor void model and the other is a convex floor tube model. For each model, optical photographs have been obtained under conditions similar to those in which optical photographs have been acquired for craters on the Moon and Mars. Brightness profiles were analyzed for determining the profile patterns of the void pit craters. The profile patterns were compared to the brightness profiles of Martian pit craters, because no good-quality images of lunar pit craters were available. In future studies, the model profile patterns will be compared to those of lunar pit craters, and the proposed method will likely become useful for finding lunar caves and consequently for planning lunar bases for manned lunar expeditions.

32 CFR 231.7 - Procedures-domestic credit unions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... maintenance (such as grass cutting and snow removal), heating and air conditioning, utilities (i.e... service shall do so in accordance with § 231.4(d). (h) Staffing. (1) On-base credit unions shall provide... counselor available to serve members during operating hours. (2) Exceptions to paragraph (h)(1)(i) of this...

32 CFR 231.7 - Procedures-domestic credit unions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... maintenance (such as grass cutting and snow removal), heating and air conditioning, utilities (i.e... service shall do so in accordance with § 231.4(d). (h) Staffing. (1) On-base credit unions shall provide... counselor available to serve members during operating hours. (2) Exceptions to paragraph (h)(1)(i) of this...

Magnetic upconverting fluorescent NaGdF4:Ln3+ and iron-oxide@NaGdF4:Ln3+ nanoparticles

NASA Astrophysics Data System (ADS)

Shrivastava, Navadeep; Rocha, Uéslen; Muraca, Diego; Jacinto, Carlos; Moreno, Sergio; Vargas, J. M.; Sharma, S. K.

2018-05-01

Microwave assisted solvothermal method has been employed to synthesize multifunctional upconverting β-NaGdF4:Ln3+ and magnetic-upconverting Fe3O4/γ-Fe2O3@NaGdF4:Ln3+ (Ln = Yb and Er) nanoparticles. The powder x-ray diffraction data confirms the hexagonal structure of NaGdF4:Ln3+ and high resolution transmission electron microscopy shows the formation of rod shaped NaGdF4:Ln3+ (˜ 20 nm) and ovoid shaped Fe3O4/γ-Fe2O3@NaGdF4:Ln3+ (˜ 15 nm) nanoparticles. The magnetic hysteresis at 300 K for β-NaGdF4:Ln3+ demonstrates paramagnetic features, whereas iron-oxide@β-NaGdF4:Ln3+ exhibits superparamagnetic behavior along with a linear component at large applied field due to paramagnetic NaGdF4 matrix. Both nanoparticle samples provide an excellent green emitting [(2H11/2, 4S3/2)→4I15/2 (˜ 540 nm)] upconversion luminescence emission under excitation at 980 nm. The energy migration between Yb and Er in NaGdF4 matrix has been explored from 300-800 nm. Intensity variation of blue, green and red lines and the observed luminescence quenching due to the presence of Fe3O4/γ-Fe2O3 in the composite has been proposed. These kinds of materials contain magnetic and luminescence characteristics into single nanoparticle open new possibility for bioimaging applications.

Pits and Channels of Hebrus Valles

NASA Image and Video Library

2017-01-26

The drainages in this image are part of Hebrus Valles, an outflow channel system likely formed by catastrophic floods. Hebrus Valles is located in the plains of the Northern lowlands, just west of the Elysium volcanic region. Individual channels range from several hundred meters to several kilometers wide and form multi-threaded (anastamosing) patterns. Separating the channels are streamlined forms, whose tails point downstream and indicate that channel flow is to the north. The channels seemingly terminate in an elongated pit that is approximately 1875 meters long and 1125 meters wide. Using the shadow that the wall has cast on the floor of the pit, we can estimate that the pit is nearly 500 meters deep. The pit, which formed after the channels, exposes a bouldery layer below the dusty surface mantle and is underlain by sediments. Boulders several meters in diameter litter the slopes down into the pit. Pits such as these are of interest as possible candidate landing sites for human exploration because they might retain subsurface water ice (Schulze-Makuch et al. 2016, 6th Mars Polar Conf.) that could be utilized by future long-term human settlements. http://photojournal.jpl.nasa.gov/catalog/PIA11704

Properties of hydrocarbon- and salt-contaminated flare pit soils in northeastern British Columbia (Canada).

PubMed

Arocena, J M; Rutherford, P M

2005-07-01

Many contaminated sites in Canada are associated with flare pits generated during past petroleum extraction operations. Flare pits are located adjacent to well sites, compressor stations and batteries and are often subjected to the disposal of wastes from the flaring of gas, liquid hydrocarbons and brine water. This study was conducted to evaluate the physical, chemical, electrical and mineral properties of three flare pit soils as compared to adjacent control soils. Results showed that particle size distribution, pH, total N, cation exchange capacity, exchangeable Mg(2+), and sodium adsorption ratio were similar in soils from flare pits and control sites. Total C, exchangeable Ca(2+), K(+) and Na(+), soluble Ca(2+), Mg(2+), K(+) and Na(+) and electrical conductivity were higher in flare pit soils compared to control soils. X-ray diffraction and scanning electron microscopic analyses showed the presence of gypsum [CaSO(4).2H(2)O], dolomite [CaMg(CO(3))(2)], pyrite [FeS(2)], jarosite [KFe(3)(OH)(6)(SO(4))(2)], magnesium sulphate, oxides of copper and iron+copper in salt efflorescence observed in flare pit soils. Soils from both flare pits and control sites contained mica, kaolonite and 2:1 expanding clays. The salt-rich materials altered the ionic equilibria in the flare pit soils; K(Mg-Ca) selectivity coefficients in control soils were higher compared to contaminated soils. The properties of soils (e.g., high electrical conductivity) affected by inputs associated with oil and gas operations might render flare pit soils less conducive to the establishment and growth of common agricultural crops and forest trees.

Faulted Layers in Collapse Pits

NASA Image and Video Library

2016-04-06

This image shows a set of coalesced collapse pits in western Valles Marineris as seen by NASA Mars Reconnaissance Orbiter. Fine layers are exposed in the walls of the pits, and in some places those layers are displaced by faults.

The PIT-trap-A "model-free" bootstrap procedure for inference about regression models with discrete, multivariate responses.

PubMed

Warton, David I; Thibaut, Loïc; Wang, Yi Alice

2017-01-01

Bootstrap methods are widely used in statistics, and bootstrapping of residuals can be especially useful in the regression context. However, difficulties are encountered extending residual resampling to regression settings where residuals are not identically distributed (thus not amenable to bootstrapping)-common examples including logistic or Poisson regression and generalizations to handle clustered or multivariate data, such as generalised estimating equations. We propose a bootstrap method based on probability integral transform (PIT-) residuals, which we call the PIT-trap, which assumes data come from some marginal distribution F of known parametric form. This method can be understood as a type of "model-free bootstrap", adapted to the problem of discrete and highly multivariate data. PIT-residuals have the key property that they are (asymptotically) pivotal. The PIT-trap thus inherits the key property, not afforded by any other residual resampling approach, that the marginal distribution of data can be preserved under PIT-trapping. This in turn enables the derivation of some standard bootstrap properties, including second-order correctness of pivotal PIT-trap test statistics. In multivariate data, bootstrapping rows of PIT-residuals affords the property that it preserves correlation in data without the need for it to be modelled, a key point of difference as compared to a parametric bootstrap. The proposed method is illustrated on an example involving multivariate abundance data in ecology, and demonstrated via simulation to have improved properties as compared to competing resampling methods.

48 CFR 352.231-70 - Precontract costs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... entitled to reimbursement for allowable, allocable, and reasonable costs incurred during the period of... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Precontract costs. 352.231... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 352.231-70 Precontract costs. As...

49 CFR 192.231 - Protection from weather.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 3 2012-10-01 2012-10-01 false Protection from weather. 192.231 Section 192.231 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... weather. The welding operation must be protected from weather conditions that would impair the quality of...

49 CFR 192.231 - Protection from weather.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 3 2010-10-01 2010-10-01 false Protection from weather. 192.231 Section 192.231 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... weather. The welding operation must be protected from weather conditions that would impair the quality of...

49 CFR 192.231 - Protection from weather.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 3 2013-10-01 2013-10-01 false Protection from weather. 192.231 Section 192.231 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... weather. The welding operation must be protected from weather conditions that would impair the quality of...

49 CFR 192.231 - Protection from weather.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 3 2014-10-01 2014-10-01 false Protection from weather. 192.231 Section 192.231 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... weather. The welding operation must be protected from weather conditions that would impair the quality of...

49 CFR 192.231 - Protection from weather.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 3 2011-10-01 2011-10-01 false Protection from weather. 192.231 Section 192.231 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... weather. The welding operation must be protected from weather conditions that would impair the quality of...

32 CFR 231.5 - Procedures-domestic banks.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Procedures-domestic banks. 231.5 Section 231.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED... Secretary of the Military Department concerned (or designee) for establishment of banking offices: (i) The...

32 CFR 231.5 - Procedures-domestic banks.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 2 2012-07-01 2012-07-01 false Procedures-domestic banks. 231.5 Section 231.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED... Secretary of the Military Department concerned (or designee) for establishment of banking offices: (i) The...

32 CFR 231.5 - Procedures-domestic banks.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 2 2013-07-01 2013-07-01 false Procedures-domestic banks. 231.5 Section 231.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED... Secretary of the Military Department concerned (or designee) for establishment of banking offices: (i) The...

40 CFR 52.231 - Regulations: Sulfur oxides.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Regulations: Sulfur oxides. 52.231... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.231 Regulations: Sulfur oxides... Ambient Air Quality Standard for Sulfur Oxides. (1) Lake County Intrastate Region. (i) Lake County, APCD...

40 CFR 52.231 - Regulations: Sulfur oxides.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Regulations: Sulfur oxides. 52.231... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.231 Regulations: Sulfur oxides... Ambient Air Quality Standard for Sulfur Oxides. (1) Lake County Intrastate Region. (i) Lake County, APCD...

40 CFR 52.231 - Regulations: Sulfur oxides.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Regulations: Sulfur oxides. 52.231... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.231 Regulations: Sulfur oxides... Ambient Air Quality Standard for Sulfur Oxides. (1) Lake County Intrastate Region. (i) Lake County, APCD...

40 CFR 52.231 - Regulations: Sulfur oxides.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Regulations: Sulfur oxides. 52.231... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.231 Regulations: Sulfur oxides... Ambient Air Quality Standard for Sulfur Oxides. (1) Lake County Intrastate Region. (i) Lake County, APCD...

40 CFR 52.231 - Regulations: Sulfur oxides.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Regulations: Sulfur oxides. 52.231... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.231 Regulations: Sulfur oxides... Ambient Air Quality Standard for Sulfur Oxides. (1) Lake County Intrastate Region. (i) Lake County, APCD...

The eIF4F and eIFiso4F Complexes of Plants: An Evolutionary Perspective

PubMed Central

Patrick, Ryan M.; Browning, Karen S.

2012-01-01

Translation initiation in eukaryotes requires a number of initiation factors to recruit the assembled ribosome to mRNA. The eIF4F complex plays a key role in initiation and is a common target point for regulation of protein synthesis. Most work on the translation machinery of plants to date has focused on flowering plants, which have both the eIF4F complex (eIF4E and eIF4G) as well as the plant-specific eIFiso4F complex (eIFiso4E and eIFiso4G). The increasing availability of plant genome sequence data has made it possible to trace the evolutionary history of these two complexes in plants, leading to several interesting discoveries. eIFiso4G is conserved throughout plants, while eIFiso4E only appears with the evolution of flowering plants. The eIF4G N-terminus, which has been difficult to annotate, appears to be well conserved throughout the plant lineage and contains two motifs of unknown function. Comparison of eIFiso4G and eIF4G sequence data suggests conserved features unique to eIFiso4G and eIF4G proteins. These findings have answered some questions about the evolutionary history of the two eIF4F complexes of plants, while raising new ones. PMID:22611336

Experimental research on micro-pit defects of SUS 430 stainless steel strip in cold rolling process

NASA Astrophysics Data System (ADS)

Li, Changsheng; Li, Miao; Zhu, Tao; Huo, Gang

2013-05-01

In order to improve surface glossiness of stainless steel strip in tandem cold rolling, experimental research on micro-pit defects of SUS 430 ferrite stainless steel was investigated in laboratory. The surface morphology of micro-pit defects was observed by SEM. The effects of micro-pit defects on rolling reduction, roll surface roughness and emulsion parameters were analyzed. With the pass number increasing, the quantity and surface of micro-pit defects were reduced, uneven peak was decreased and gently along rolling direction, micro-pit defects had equally distributed tendency along tranverse direction. The micro-pit defects were increased with the roll surface roughness increase. The defects ratio was declined with larger gradient at pass number 1 to 3, but gentle slope at pass number 4 to 5. The effects of temperature 55° and 63°, concentration 3% and 6% of emulsion on micro-pit effects had not obvious difference. Maintain of micro-pit was effected by rolling oil or air in the micro-pit, the quality of oil was much more than the air in the micro-pit in lubrication rolling.

Distribution, formation mechanisms, and significance of lunar pits

NASA Astrophysics Data System (ADS)

Wagner, Robert V.; Robinson, Mark S.

2014-07-01

Lunar Reconnaissance Orbiter Camera images reveal the presence of steep-walled pits in mare basalt (n = 8), impact melt deposits (n = 221), and highland terrain (n = 2). Pits represent evidence of subsurface voids of unknown extents. By analogy with terrestrial counterparts, the voids associated with mare pits may extend for hundreds of meters to kilometers in length, thereby providing extensive potential habitats and access to subsurface geology. Because of their small sizes relative to the local equilibrium crater diameters, the mare pits are likely to be post-flow features rather than volcanic skylights. The impact melt pits are indirect evidence both of extensive subsurface movement of impact melt and of exploitable sublunarean voids. Due to the small sizes of pits (mare, highland, and impact melt) and the absolute ages of their host materials, it is likely that most pits formed as secondary features.

The efficiencies of cast blasting in wide pits

DOE Office of Scientific and Technical Information (OSTI.GOV)

Martin, R.L.; King, M.G.

Blasting activities in all four pits at Thunder Basin Coal`s Black Thunder Mine are focused on cast blasting. With widths varying from 190 feet to 265 feet and bench heights varying from 90 feet to 175 feet, casting efficiencies vary with different geometry`s. For example, the percent cast to final in the 200 foot pit is on the average higher than the 270 foot pit. The powder factors are somewhat higher in the narrower pits, thus increasing the cost of blasting. This leads to a very detailed look at the actual benefit of cast blasting and the associated cost ofmore » these benefits. The simple solution would be to reduce the width of the pits, thereby increasing the percent cast to final. However, the lower rehandle and low coal loss associated with wide pits would be fortified. Upon further review it becomes obvious that the wider pits could not be compared to the narrow pits with the cast to final percent indices. The focus should be shifted to cubic yards cast to final per lineal foot of pit. This will allow for more accurate measures of the casting efficiency of the shot. When comparing the pits with these indices their performances were much closer than the percent cast to final indices. The powder factors being higher in the narrow pits drove up the cost per cubic yard cast to final. Therefore, even though the percent cast to final was higher, the cost per cubic yard was also higher.« less

Pou4f1 and Pou4f2 Are Dispensable for the Long-Term Survival of Adult Retinal Ganglion Cells in Mice

PubMed Central

Huang, Liang; Hu, Fang; Xie, Xiaoling; Harder, Jeffery; Fernandes, Kimberly; Zeng, Xiang-yun; Libby, Richard; Gan, Lin

2014-01-01

Purpose To investigate the role of Pou4f1 and Pou4f2 in the survival of adult retinal ganglion cells (RGCs). Methods Conditional alleles of Pou4f1 and Pou4f2 were generated (Pou4f1loxP and Pou4f2loxP respectively) for the removal of Pou4f1 and Pou4f2 in adult retinas. A tamoxifen-inducible Cre was used to delete Pou4f1 and Pou4f2 in adult mice and retinal sections and flat mounts were subjected to immunohistochemistry to confirm the deletion of both alleles and to quantify the changes in the number of RGCs and other retinal neurons. To determine the effect of loss of Pou4f1 and Pou4f2 on RGC survival after axonal injury, controlled optic nerve crush (CONC) was performed and RGC death was assessed. Results Pou4f1 and Pou4f2 were ablated two weeks after tamoxifen treatment. Retinal interneurons and Müller glial cells are not affected by the ablation of Pou4f1 or Pou4f2 or both. Although the deletion of both Pou4f1 and Pou4f2 slightly delays the death of RGCs at 3 days post-CONC in adult mice, it does not affect the cell death progress afterwards. Moreoever, deletion of Pou4f1 or Pou4f2 or both has no impact on the long-term viability of RGCs at up to 6 months post-tamoxifen treatment. Conclusion Pou4f1 and Pou4f2 are involved in the acute response to damage to RGCs but are dispensable for the long-term survival of adult RGC in mice. PMID:24736625

Evaluation of methods for attaching PIT tags and biotelemetry devices to freshwater mussels

USGS Publications Warehouse

Young, S.P.; Isely, J.J.

2008-01-01

We evaluated methods to attach PIT tags and transmitters to freshwater mussels. Mussels received externally-mounted PIT tags using cyanoacrylate or underwater epoxy, and a sub-group of those with PIT tags attached using cyanoacrylate also received dummy transmitters. Tag retention and survival were 100% after a 30 day laboratory observation period for each method. During the subsequent 18 months of field observation, underwater epoxy and cyanoacrylate proved to be adequate adhesives for attaching PIT tags and transmitters. Epoxy performed best with 100% PIT tag retention. Cyanoacrylate also provided high retention rates of PIT tags and transmitters, >90%. Mortality was minimal at 4.7% for all relocated mussels over 18 months. All mortalities were those tagged with cyanoacrylate. Three of the mortalities occurred among mussels fitted with dummy transmitters, and seven among PIT tags only. Percent recapture of the different tag/adhesive combinations ranged from 48 - 77.5% during 6- and 18-month surveys. Results suggest both adhesives provide a reliable method for external attachment of tags during freshwater mussel research; however, epoxy may be better suited because of slightly higher tag retention and reduced emersion times during attachment. Copyright ?? 2008 Malacological Society of Australasia.

22 CFR 231.13 - Change in agreements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Change in agreements. 231.13 Section 231.13 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

22 CFR 231.13 - Change in agreements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Change in agreements. 231.13 Section 231.13 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

22 CFR 231.13 - Change in agreements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Change in agreements. 231.13 Section 231.13 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

22 CFR 231.11 - Subrogation of USAID.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Subrogation of USAID. 231.11 Section 231.11 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

22 CFR 231.07 - Fiscal Agent obligations.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Fiscal Agent obligations. 231.07 Section 231.07 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

22 CFR 231.07 - Fiscal Agent obligations.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Fiscal Agent obligations. 231.07 Section 231.07 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

22 CFR 231.11 - Subrogation of USAID.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Subrogation of USAID. 231.11 Section 231.11 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

22 CFR 231.12 - Prosecution of claims.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Prosecution of claims. 231.12 Section 231.12 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

22 CFR 231.12 - Prosecution of claims.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Prosecution of claims. 231.12 Section 231.12 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

22 CFR 231.07 - Fiscal Agent obligations.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Fiscal Agent obligations. 231.07 Section 231.07 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

22 CFR 231.13 - Change in agreements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Change in agreements. 231.13 Section 231.13 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

22 CFR 231.12 - Prosecution of claims.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Prosecution of claims. 231.12 Section 231.12 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

22 CFR 231.11 - Subrogation of USAID.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Subrogation of USAID. 231.11 Section 231.11 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

22 CFR 231.07 - Fiscal Agent obligations.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Fiscal Agent obligations. 231.07 Section 231.07 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

22 CFR 231.12 - Prosecution of claims.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Prosecution of claims. 231.12 Section 231.12 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

22 CFR 231.13 - Change in agreements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Change in agreements. 231.13 Section 231.13 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

22 CFR 231.11 - Subrogation of USAID.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Subrogation of USAID. 231.11 Section 231.11 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ARAB REPUBLIC OF EGYPT LOAN GUARANTEES ISSUED UNDER THE EMERGENCY WARTIME SUPPLEMENTAL APPROPRIATIONS ACT OF 2003, PUBLIC LAW 108-11-STANDARD TERMS AND...

48 CFR 1852.231-70 - Precontract costs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 1852.231-70 Precontract costs. As prescribed in 1831.205-70, insert the following clause: Precontract Costs (JUN 1995) The contractor shall be entitled to reimbursement for costs incurred on or after... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Precontract costs. 1852.231...

Lunar Pit Craters Presumed to be the Entrances of Lava Caves by Analogy to the Earth Lava Tube Pits

NASA Astrophysics Data System (ADS)

Hong, Ik-Seon; Yi, Yu; Kim, Eojin

2014-06-01

Lava caves could be useful as outposts for the human exploration of the Moon. Lava caves or lava tubes are formed when the external surface of the lava flows cools more quickly to make a hardened crust over subsurface lava flows. The lava flow eventually ceases and drains out of the tube, leaving an empty space. The frail part of the ceiling of lava tube could collapse to expose the entrance to the lava tubes which is called a pit crater. Several pit craters with the diameter of around 100 meters have been found by analyzing the data of SELENE and LRO lunar missions. It is hard to use these pit craters for outposts since these are too large in scale. In this study, small scale pit craters which are fit for outposts have been investigated using the NAC image data of LROC. Several topographic patterns which are believed to be lunar caves have been found and the similar pit craters of the Earth were compared and analyzed to identify caves. For this analysis, the image data of satellites and aerial photographs are collected and classified to construct a database. Several pit craters analogous to lunar pit craters were derived and a morphological pit crater model was generated using the 3D printer based on this database.

27 CFR 9.231 - Moon Mountain District Sonoma County.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Moon Mountain District Sonoma County. 9.231 Section 9.231 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL AMERICAN VITICULTURAL AREAS Approved American Viticultural Areas § 9.231 Moon Mountain District Sonom...

Low-speed impacts between rubble piles modeled as collections of polyhedra

NASA Astrophysics Data System (ADS)

Korycansky, D. G.; Asphaug, Erik

2006-04-01

We present results of modeling rubble piles as collections of polyhedra. The use of polyhedra allows more realistic (irregular) shapes and interactions (e.g. collisions), particularly for objects of different sizes. Rotational degrees of freedom are included in the modeling, which may be important components of the motion. We solved the equations of rigid-body dynamics, including frictional/inelastic collisions, for collections of up to several hundred elements. As a demonstration of the methods and to compare with previous work by other researchers, we simulated low-speed collisions between km-scale bodies with the same general parameters as those simulated by Leinhardt et al. [Leinhardt, Z.M., Richardson, D.C., Quinn, T., 2000. Icarus 146, 133-151]. High-speed collisions appropriate to present-day asteroid encounters require additional treatment of shock effects and fragmentation and are the subject of future work; here we study regimes appropriate to planetesimal accretion and re-accretion in the aftermath of catastrophic events. Collisions between equal-mass objects at low speeds ( <10 cms) were simulated for both head-on and off-center collisions between rubble piles made of a power-law mass spectrum of sub-elements. Very low-speed head-on collisions produce single objects from the coalescence of the impactors. For slightly higher speeds, extensive disruption occurs, but re-accretion produces a single object with most of the total mass. For increasingly higher speeds, the re-accreted object has smaller mass, finally resulting in complete catastrophic disruption with all sub-elements on escape trajectories and only small amounts of mass in re-accreted bodies. Off-center collisions at moderately low speeds produce two re-accreted objects of approximately equal mass, separating at greater than escape speed. At high speed, complete disruption occurs as with the high-speed head-on collisions. Head-on collisions at low to moderate speeds result in objects of mostly

Sublimation pit distribution indicates convection cell surface velocities of ∼10 cm per year in Sputnik Planitia, Pluto

NASA Astrophysics Data System (ADS)

Buhler, Peter B.; Ingersoll, Andrew P.

2018-01-01

The ∼106 km2 Sputnik Planitia, Pluto is the upper surface of a vast basin of nitrogen ice. Cellular landforms in Sputnik Planitia with areas in the range of a few × 102-103 km2 are likely the surface manifestation of convective overturn in the nitrogen ice. The cells have sublimation pits on them, with smaller pits near their centers and larger pits near their edges. We map pits on seven cells and find that the pit radii increase by between 2.1 ± 0.4 × 10-3 and 5.9 ± 0.8 × 10-3 m m-1 away from the cell center, depending on the cell. This is a lower bound on the size increase because of the finite resolution of the data. Accounting for resolution yields upper bounds on the size vs. distance distribution of between 4.2 ± 0.2 × 10-3 and 23.4 ± 1.5 × 10-3 m m-1. We then use an analytic model to calculate that pit radii grow via sublimation at a rate of 3.6-0.6+2.1 ×10-4 m yr-1, which allows us to convert the pit size vs. distance distribution into a pit age vs. distance distribution. This yields surface velocities between 1.5-0.2+1.0 and 6.2-1.4+3.4 cm yr-1 for the slowest cell and surface velocities between 8.1-1.0+5.5 and 17.9-5.1+8.9 cm yr-1 for the fastest cell. These convection rates imply that the surface ages at the edge of cells reach ∼4.2-8.9 × 105 yr. The rates are comparable to rates of ∼6 cm yr-1 that were previously obtained from modeling of the convective overturn in Sputnik Planitia (McKinnon et al., 2016). Finally, we investigate the surface rheology of the convection cells and estimate that the minimum ice viscosity necessary to support the geometry of the observed pits is of order 1016-1017 Pa s, based on the argument that pits would relax away before growing to their observed radii of several hundred meters if the viscosity were lower than this value.

Sputnik Planitia, Pluto Convection Cell Surface Velocities of ~10 Centimeters per Year Based on Sublimation Pit Distribution

NASA Astrophysics Data System (ADS)

Buhler, Peter Benjamin; Ingersoll, Andrew P.

2017-10-01

Sputnik Planitia, Pluto contains cellular landforms with areas on the order of a few 102-103 km2 that are likely the surface manifestation of convective overturn in a vast basin of nitrogen ice. The cells have sublimation pits on them, with smaller pits near their centers and larger pits near their edges. We map over 12,000 pits on seven cells and find that the pit radii increase by between 2.1 ± 0.4 and 5.9 ± 0.8 × 10-3 m per meter away from the cell center, depending on the cell. Due to finite data resolution, this is a lower bound on the size increase. Conservatively accounting for resolution effects yields upper bounds on the size vs. distance distribution of 4.2 ± 0.2 to 23.4 ± 1.5 × 10-3 m m-1. In order to convert the pit size vs. distance distribution into a pit age vs. distance distribution, we use an analytic model to calculate that pit radii grow via sublimation at a rate of 3.6 [+2.1,-0.6] × 10-4 m yr-1. Combined with the mapped distribution of pit radii, this yields surface velocities between 1.5 [+1.0,-0.2] and 6.2 [+3.4,-1.4] cm yr-1 for the slowest cell and surface velocities between 8.1 [+5.5,-1.0] and 17.9 [+8.9,-5.1] cm yr-1 for the fastest cell; the lower bound estimate for each cell accounts for resolution effects, while the upper bound estimate does not. These convection rates imply that the surface ages at the edge of cells reach approximately 4.2 to 8.9 × 105 yr, depending on the cell. The rates we find are comparable to rates of ~6 cm yr-1 that were previously obtained from modeling of the convective overturn in Sputnik Planitia [McKinnon, W.B. et al., 2016, Nature, 534(7605), 82-85]. Finally, we find that the minimum viscosity at the surface of the convection cells is of order 1016 to 1017 Pa s; we find that pits would relax away before sublimating to their observed radii of several hundred meters if the viscosity were lower than this value.

Elmendorf AFB, Anchorage, Alaska. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F

DTIC Science & Technology

1979-09-17

APR MAY JUN JUL AUG SEP. OCT NOV. DEC. MONTHS YEAR II L 1 41 o -4L, 231 291 341 341 401 241 14 - 12 -171 2-C -2.u; -L- . 2 L 29 3- 46! 41 25 1 -16 -281...ANCHORAGL 07-76 FEB STATION STATION NAME YEARS MONTN c PAGE 2 0900-1100 4 NHOURS (L. S. T.) Tomp 0 12 5. . WET BULB TEMPERATURE DEPRESSION (F) TOTAL...34_ _ FEB STATION STATION NAME YEARS MONTH 0 PAGE 1 1500-1700 Temp. WET BULB TEMPER, TURE DEPRESSION (F) TOTAL TOTAL lF) 01- -.2 3.4 5.6 7 .8 19.10 11- 12

Illuminating Anaerobic Microbial Community and Cooccurrence Patterns across a Quality Gradient in Chinese Liquor Fermentation Pit Muds

PubMed Central

Hu, Xiaolong; Du, Hai; Ren, Cong

2016-01-01

Fermentation pit mud, an important reservoir of diverse anaerobic microorganisms, is essential for Chinese strong-aroma liquor production. Pit mud quality, according to its sensory characteristics, can be divided into three grades: degraded, normal, and high quality. However, the relationship between pit mud microbial community and pit mud quality is poorly understood, as are microbial associations within the pit mud ecosystem. Here, microbial communities at these grades were compared using Illumina MiSeq sequencing of the variable region V4 of the 16S rRNA gene. Our results revealed that the pit mud microbial community was correlated with its quality and environmental factors. Species richness, biodiversity, and relative and/or absolute abundances of Clostridia, Clostridium kluyveri, Bacteroidia, and Methanobacteria significantly increased, with corresponding increases in levels of pH, NH4+, and available phosphorus, from degraded to high-quality pit muds, while levels of Lactobacillus, dissolved organic carbon, and lactate significantly decreased, with normal samples in between. Furthermore, 271 pairs of significant and robust correlations (cooccurrence and negative) were identified from 76 genera using network analysis. Thirteen hubs of cooccurrence patterns, mainly under the Clostridia, Bacteroidia, Methanobacteria, and Methanomicrobia, may play important roles in pit mud ecosystem stability, which may be destroyed with rapidly increased levels of lactic acid bacteria (Lactobacillus, Pediococcus, and Streptococcus). This study may help clarify the relationships among microbial community, environmental conditions, and pit mud quality, allow the improvement of pit mud quality by using bioaugmentation and controlling environmental factors, and shed more light on the ecological rules guiding community assembly in pit mud. PMID:26896127

Distribution, morphology, and origins of Martian pit crater chains

NASA Astrophysics Data System (ADS)

Wyrick, Danielle; Ferrill, David A.; Morris, Alan P.; Colton, Shannon L.; Sims, Darrell W.

2004-06-01

Pit craters are circular to elliptical depressions found in alignments (chains), which in many cases coalesce into linear troughs. They are common on the surface of Mars and similar to features observed on Earth and other terrestrial bodies. Pit craters lack an elevated rim, ejecta deposits, or lava flows that are associated with impact craters or calderas. It is generally agreed that the pits are formed by collapse into a subsurface cavity or explosive eruption. Hypotheses regarding the formation of pit crater chains require development of a substantial subsurface void to accommodate collapse of the overlying material. Suggested mechanisms of formation include: collapsed lava tubes, dike swarms, collapsed magma chamber, substrate dissolution (analogous to terrestrial karst), fissuring beneath loose material, and dilational faulting. The research described here is intended to constrain current interpretations of pit crater chain formation by analyzing their distribution and morphology. The western hemisphere of Mars was systematically mapped using Mars Orbiter Camera (MOC) images to generate ArcView™ Geographic Information System (GIS) coverages. All visible pit crater chains were mapped, including their orientations and associations with other structures. We found that pit chains commonly occur in areas that show regional extension or local fissuring. There is a strong correlation between pit chains and fault-bounded grabens. Frequently, there are transitions along strike from (1) visible faulting to (2) faults and pits to (3) pits alone. We performed a detailed quantitative analysis of pit crater morphology using MOC narrow angle images, Thermal Emission Imaging System (THEMIS) visual images, and Mars Orbiter Laser Altimeter (MOLA) data. This allowed us to determine a pattern of pit chain evolution and calculate pit depth, slope, and volume. Volumes of approximately 150 pits from five areas were calculated to determine volume size distribution and regional

Electrochemical analysis of the corrosion inhibition effect of trypsin complex on the pitting corrosion of 420 martensitic stainless steel in 2M H2SO4 solution.

PubMed

Loto, Roland Tolulope

2018-01-01

Inhibition effect of trypsin complex (TC) on the pitting corrosion of martensitic stainless steel (type 420) in 1M H2SO4 solution was studied with potentiodynamic polarization, open circuit potential measurement and optical microscopy. TC reduced the corrosion rate of the steel with maximum inhibition efficiency of 80.75%. Corrosion potential shifted anodically due to the electrochemical action of TC. The pitting potential increased from 1.088VAg/AgCl (3M) at 0% TC to 1.365VAg/AgCl(3M) at 4% TC. TC shifts the open circuit corrosion potential from -0.270s at 0% TC concentration to -0.255V at 5% TC. The compound completely adsorbed onto the steel according to Langmuir, Frumkin and Temkin isotherms. ATF-FTIR spectroscopy confirmed the inhibition mode to be through surface coverage. Thermodynamic calculations showed physisorption molecular interaction. Corrosion pits are present on the uninhibited 420 morphology in comparison to TC inhibited surface which slightly deteriorated.

Electrochemical analysis of the corrosion inhibition effect of trypsin complex on the pitting corrosion of 420 martensitic stainless steel in 2M H2SO4 solution

PubMed Central

Loto, Roland Tolulope

2018-01-01

Inhibition effect of trypsin complex (TC) on the pitting corrosion of martensitic stainless steel (type 420) in 1M H2SO4 solution was studied with potentiodynamic polarization, open circuit potential measurement and optical microscopy. TC reduced the corrosion rate of the steel with maximum inhibition efficiency of 80.75%. Corrosion potential shifted anodically due to the electrochemical action of TC. The pitting potential increased from 1.088VAg/AgCl (3M) at 0% TC to 1.365VAg/AgCl(3M) at 4% TC. TC shifts the open circuit corrosion potential from -0.270s at 0% TC concentration to -0.255V at 5% TC. The compound completely adsorbed onto the steel according to Langmuir, Frumkin and Temkin isotherms. ATF-FTIR spectroscopy confirmed the inhibition mode to be through surface coverage. Thermodynamic calculations showed physisorption molecular interaction. Corrosion pits are present on the uninhibited 420 morphology in comparison to TC inhibited surface which slightly deteriorated. PMID:29672541

The PIT-trap—A “model-free” bootstrap procedure for inference about regression models with discrete, multivariate responses

PubMed Central

Thibaut, Loïc; Wang, Yi Alice

2017-01-01

Bootstrap methods are widely used in statistics, and bootstrapping of residuals can be especially useful in the regression context. However, difficulties are encountered extending residual resampling to regression settings where residuals are not identically distributed (thus not amenable to bootstrapping)—common examples including logistic or Poisson regression and generalizations to handle clustered or multivariate data, such as generalised estimating equations. We propose a bootstrap method based on probability integral transform (PIT-) residuals, which we call the PIT-trap, which assumes data come from some marginal distribution F of known parametric form. This method can be understood as a type of “model-free bootstrap”, adapted to the problem of discrete and highly multivariate data. PIT-residuals have the key property that they are (asymptotically) pivotal. The PIT-trap thus inherits the key property, not afforded by any other residual resampling approach, that the marginal distribution of data can be preserved under PIT-trapping. This in turn enables the derivation of some standard bootstrap properties, including second-order correctness of pivotal PIT-trap test statistics. In multivariate data, bootstrapping rows of PIT-residuals affords the property that it preserves correlation in data without the need for it to be modelled, a key point of difference as compared to a parametric bootstrap. The proposed method is illustrated on an example involving multivariate abundance data in ecology, and demonstrated via simulation to have improved properties as compared to competing resampling methods. PMID:28738071

Comparative expression analysis of POU4F1, POU4F2 and ISL1 in developing mouse cochleovestibular ganglion neurons

PubMed Central

Deng, Min; Yang, Hua; Xie, Xiaoling; Liang, Guoqing; Gan, Lin

2014-01-01

POU-homeodomain and LIM-homeodomain transcription factors are expressed in developing projection neurons within retina, inner ear, dorsal root ganglion, and trigeminal ganglion, and play synergistic roles in their differentiation and survival. Here, using immunohistochemistry, we present a comparative analysis of the spatiotemporal expression pattern of POU4F1, POU4F2, and ISL1 during the development of cochleovestibular ganglion (CVG) neurons in mouse inner ear. At early stages, when otic neurons are first detected in the otic epithelium (OE) and migrate into periotic mesenchyme to form the CVG, POU4F1 and ISL1 are co-expressed in a majority of the delaminated CVG neurons, which are marked by NEUROD1 expression, but POU4F1 is absent in the otic epithelium. The onset of POU4F2 expression starts after that of POU4F1 and ISL1, and is observed in the NEUROD1-negative, post-mitotic CVG neurons. When the CVG neurons innervate the vestibular and cochlear sensory organs, the expression of POU4F1, POU4F2, and ISL1 continues in both vestibular and spiral ganglion cells. Later in development, POU4F1 expression becomes down-regulated in a majority of spiral ganglion (SG) neurons and more neurons express POU4F2 expression while ISL1 expression is maintained. The differential as well as overlapping expression of POU4F1, POU4F2, and ISL1 combined with previous studies suggests possible functional interaction and regulatory relationship of these transcription factors in the development of inner ear neurons. PMID:24709358

Isolation and purification of protactinium-231.

PubMed

Jerome, S M; Collins, S M; Happel, S; Ivanov, P; Russell, B C

2018-04-01

Protactinium-231 is one of the lesser known actinides, yet the measurement of this radionuclide is central to dating studies in both paleoclimate and nuclear forensics measurements; furthermore, it is important as the immediate parent nuclide of the 227 Ac decay chain. In this paper, we present the preparatory work for an upcoming CCRI(II) supplementary comparison of this radionuclide. The material used in this work was of poorly known provenance, and it was necessary to carry out a chemical purification of this material prior to use. A new extraction chromatography resin, TK 400, which has been developed for the separation of 231 Pa, was tested at NPL. The aims of the work were achieved; the recovery of 231 Pa was ~85%, the decay products were recovered in good yield (~95%) and stable element impurities were removed. Copyright © 2017. Published by Elsevier Ltd.

Algorithms for detecting cherry pits on the basis of transmittance mode hyperspectral data

NASA Astrophysics Data System (ADS)

Siedliska, Anna; Zubik, Monika; Baranowski, Piotr; Mazurek, Wojciech

2017-10-01

The suitability of the hyperspectral transmittance imaging technique was assessed in terms of detecting the internal intrusions (pits and their fragments) in cherries. Herein, hyperspectral transmission images were acquired in the visible and near-infrared range (450-1000 nm) from pitted and intact cherries of three popular cultivars: `Łutówka', `Pandy 103', and `Groniasta', differing by soluble solid content. The hyperspectral transmittance data of fresh cherries were used to determine the influence of differing soluble solid content in fruit tissues on pit detection effectiveness. Models for predicting the soluble solid content of cherries were also developed. The principal component analysis and the second derivative pre-treatment of the hyperspectral data were used to construct the supervised classification models. In this study, five classifiers were tested for pit detection. From all the classifiers studied, the best prediction accuracies for the whole pit or pit fragment detection were obtained via the backpropagation neural networks model (87.6% of correctly classified instances for the training/test set and 81.4% for the validation set). The accuracy of distinguishing between drilled and intact cherries was close to 96%. These results showed that the hyperspectral transmittance imaging technique is feasible and useful for the non-destructive detection of pits in cherries.

Hood River PIT-tag interrogation system efficiency study. Annual report of U.S. Geological Survey activities: November 2010-October 2011

USGS Publications Warehouse

Jezorek, Ian G.; Connolly, Patrick J.

2012-01-01

An additional USGS-CRRL task, under contract number 50150, was to build three antennas for use with Destron-Fearing 2001F-ISO PIT tag readers. These antennas would be 5 used at the East Fork Hood River Acclimation site. They would be placed in the outflow channel to inform managers about the number of PIT tagged steelhead smolts released to the Hood River after a period of acclimation when some mortality and predation might occur. 

48 CFR 231.205-1 - Public relations and advertising costs.

Code of Federal Regulations, 2011 CFR

2011-10-01

... advertising costs. 231.205-1 Section 231.205-1 Federal Acquisition Regulations System DEFENSE ACQUISITION... PROCEDURES Contracts With Commercial Organizations 231.205-1 Public relations and advertising costs. (e) See... public relations and advertising costs also include monies paid to the Government associated with the...

Clostridium botulinum strains producing BoNT/F4 or BoNT/F5.

PubMed

Raphael, Brian H; Bradshaw, Marite; Kalb, Suzanne R; Joseph, Lavin A; Lúquez, Carolina; Barr, John R; Johnson, Eric A; Maslanka, Susan E

2014-05-01

Botulinum neurotoxin type F (BoNT/F) may be produced by Clostridium botulinum alone or in combination with another toxin type such as BoNT/A or BoNT/B. Type F neurotoxin gene sequences have been further classified into seven toxin subtypes. Recently, the genome sequence of one strain of C. botulinum (Af84) was shown to contain three neurotoxin genes (bont/F4, bont/F5, and bont/A2). In this study, eight strains containing bont/F4 and seven strains containing bont/F5 were examined. Culture supernatants produced by these strains were incubated with BoNT/F-specific peptide substrates. Cleavage products of these peptides were subjected to mass spectral analysis, allowing detection of the BoNT/F subtypes present in the culture supernatants. PCR analysis demonstrated that a plasmid-specific marker (PL-6) was observed only among strains containing bont/F5. Among these strains, Southern hybridization revealed the presence of an approximately 242-kb plasmid harboring bont/F5. Genome sequencing of four of these strains revealed that the genomic backgrounds of strains harboring either bont/F4 or bont/F5 are diverse. None of the strains analyzed in this study were shown to produce BoNT/F4 and BoNT/F5 simultaneously, suggesting that strain Af84 is unusual. Finally, these data support a role for the mobility of a bont/F5-carrying plasmid among strains of diverse genomic backgrounds.

Illuminating Anaerobic Microbial Community and Cooccurrence Patterns across a Quality Gradient in Chinese Liquor Fermentation Pit Muds.

PubMed

Hu, Xiaolong; Du, Hai; Ren, Cong; Xu, Yan

2016-04-01

Fermentation pit mud, an important reservoir of diverse anaerobic microorganisms, is essential for Chinese strong-aroma liquor production. Pit mud quality, according to its sensory characteristics, can be divided into three grades: degraded, normal, and high quality. However, the relationship between pit mud microbial community and pit mud quality is poorly understood, as are microbial associations within the pit mud ecosystem. Here, microbial communities at these grades were compared using Illumina MiSeq sequencing of the variable region V4 of the 16S rRNA gene. Our results revealed that the pit mud microbial community was correlated with its quality and environmental factors. Species richness, biodiversity, and relative and/or absolute abundances of Clostridia,Clostridium kluyveri, Bacteroidia, and Methanobacteria significantly increased, with corresponding increases in levels of pH, NH4 (+), and available phosphorus, from degraded to high-quality pit muds, while levels of Lactobacillus, dissolved organic carbon, and lactate significantly decreased, with normal samples in between. Furthermore, 271 pairs of significant and robust correlations (cooccurrence and negative) were identified from 76 genera using network analysis. Thirteen hubs of cooccurrence patterns, mainly under the Clostridia,Bacteroidia,Methanobacteria, and Methanomicrobia, may play important roles in pit mud ecosystem stability, which may be destroyed with rapidly increased levels of lactic acid bacteria (Lactobacillus,Pediococcus, and Streptococcus). This study may help clarify the relationships among microbial community, environmental conditions, and pit mud quality, allow the improvement of pit mud quality by using bioaugmentation and controlling environmental factors, and shed more light on the ecological rules guiding community assembly in pit mud. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

A geochemical view into continental palaeotemperatures of the end-Permian using oxygen and hydrogen isotope composition of secondary silica in chert rubble breccia: Kaibab Formation, Grand Canyon (USA).

PubMed

Kenny, Ray

2018-01-16

The upper carbonate member of the Kaibab Formation in northern Arizona (USA) was subaerially exposed during the end Permian and contains fractured and zoned chert rubble lag deposits typical of karst topography. The karst chert rubble has secondary (authigenic) silica precipitates suitable for estimating continental weathering temperatures during the end Permian karst event. New oxygen and hydrogen isotope ratios of secondary silica precipitates in the residual rubble breccia: (1) yield continental palaeotemperature estimates between 17 and 22 °C; and, (2) indicate that meteoric water played a role in the crystallization history of the secondary silica. The continental palaeotemperatures presented herein are broadly consistent with a global mean temperature estimate of 18.2 °C for the latest Permian derived from published climate system models. Few data sets are presently available that allow even approximate quantitative estimates of regional continental palaeotemperatures. These data provide a basis for better understanding the end Permian palaeoclimate at a seasonally-tropical latitude along the western shoreline of Pangaea.

Kinetics of Cathode Processes in Separation of Thorium from Molten Salts. Part I. Investigation of ThF$sub 4$ and ThF$sub 4$-CaF$sub 2$; KINETYKA PROCESU KATODOWEGO PRZY OSADZANIU TORU ZE STOPIONYCH SOLI. CZESC I. BADANIA ThF$sub 4$ I ThF$sub 4$-CaF$sub 2$

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mints, S.; Rafal'skii, V.

1961-09-01

The current-intensity curves of non-electrolyzed salts and the curves of time-intensity and current-intensity in electrolyzed salts were plotted for molten ThF/sub 4/ and ThF /sub 4/CaF/sub 2/. The intensity of salt disintegration was determined, and electric conductivity in electrolyte was observed. (trauth)

Appearance of the pituitary factor Pit-1 increases chromatin remodeling at hypersensitive site III in the human GH locus.

PubMed

Yang, Xiaoyang; Jin, Yan; Cattini, Peter A

2010-07-01

Expression of pituitary and placental members of the human GH and chorionic somatomammotropin (CS) gene family is directed by an upstream remote locus control region (LCR). Pituitary-specific expression of GH requires direct binding of Pit-1 (listed as POU1F1 in the HUGO database) to sequences marked by a hypersensitive site (HS) region (HS I/II) 14.6 kb upstream of the GH-N gene (listed as GH1 in the HUGO database). We used human embryonic kidney 293 (HEK293) cells overexpressing wild-type and mutant Pit-1 proteins as a model system to gain insight into the mechanism by which Pit-1 gains access to the GH LCR. Addition of Pit-1 to these cells increased DNA accessibility at HS III, located 28 kb upstream of the human GH-N gene, in a POU homeodomain-dependent manner, as reflected by effects on histone hyperacetylation and RNA polymerase II activity. Direct binding of Pit-1 to HS III sequences is not supported. However, the potential for binding of ETS family members to this region has been demonstrated, and Pit-1 association with this ETS element in HS III sequences requires the POU homeodomain. Also, both ETS1 and ELK1 co-precipitate from human pituitary extracts using two independent sources of Pit-1 antibodies. Finally, overexpression of ELK1 or Pit-1 expression in HEK293 cells increased GH-N RNA levels. However, while ELK1 overexpression also stimulated placental CS RNA levels, the effect of Pit-1 appeared to correlate with ETS factor levels and target GH-N preferentially. These data are consistent with recruitment and an early role for Pit-1 in remodeling of the GH LCR at the constitutively open HS III through protein-protein interaction.

Pit initiation on nitinol in simulated physiological solutions.

PubMed

Pound, Bruce G

2018-05-01

Inclusions appear to play a crucial role in the initiation of pitting on nitinol, but the reason remains unclear. Furthermore, it has not been established whether the type of inclusion is a central factor. In this study, potentiodynamic polarization together with scanning electron microscopy and energy dispersive X-ray spectroscopy were used to provide more insight into the initiation of pits on electropolished nitinol wire. Corrosion was limited to a single primary pit on each of the few wire samples that exhibited breakdown. The pit contained numerous Ti 2 NiO x inclusions, but secondary pits that developed within the primary pit provided evidence that these inclusions were the sites of pit initiation. Although several theories have been proposed to account for pit initiation at inclusions in mechanically polished and electropolished nitinol, titanium depletion in the adjacent alloy matrix appears to provide the most viable explanation. The key factor appears to be the size of the inclusion and therefore the extent of titanium depletion in the alloy matrix. The type of inclusion evidently plays a secondary role at most. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 1605-1610, 2018. © 2017 Wiley Periodicals, Inc.

Pits on Ascraeus

NASA Technical Reports Server (NTRS)

2005-01-01

24 September 2005 This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows collapse pits and troughs on the lower northeast flank of the giant martian volcano, Ascraeus Mons. Layers of volcanic rock are evident in some of the pit and valley walls, and boulders the size of houses and trucks that were liberated from these walls by gravity can be seen on the floors of the depressions.

Location near: 13.6oN, 102.6oW Image width: width: 3 km (1.9 mi) Illumination from: lower left Season: Northern Autumn

Repair, Evaluation, Maintenance, and Rehabilitation Research Program. Stability of Toe Berm Armor Stone and Toe Buttressing Stone on Rubble-Mound Breakwaters and Jetties. Physical Model Investigation

DTIC Science & Technology

1989-09-01

Rehabilitation of Rubble-Mound Structure Toes. The first objective of this work unit was to gain an iinderstanding of the toe stability problems experi- enced ...6.75-FT WAVE FLUMES 12.0- 11.0 - Be10.0- z 0 8.0 0 n- 7.0- _U Z 0 0 6.0 --- (0cc 5.0- h 0 0 LADo cc 4.0 0 . 0 -3 -P - -2 - - 01.0-0.0- - 0_0 co 2.0

Structural study of the ammonium octafluoroneptunate, [NH 4] 4NpF 8

DOE PAGES

Poineau, Frederic; Silva, Chinthaka M.; Yeamans, Charles B.; ...

2016-04-21

The [NH 4] 4NpF 8 salt was prepared from the solid-state reaction of NpO 2 with NH 4HF 2 and characterized by powder X-ray diffraction and X-ray absorption fine structure spectroscopy. The diffraction results confirm the compound to be isostructural to [NH 4] 4UF 8 with the following lattice parameter (a = 13.054(4) Å, b = 6.681(2) Å, c = 13.676(5) Å, ß = 121.14 Å). For the first time, a Neptunium fluoride complex has been characterized by XAFS spectroscopy. The energy position of the white line and inflection of the XANES spectra of [NH 4] 4NpF 8 are consistentmore » with the presence of Np(IV). Adjustment of the EXAFS spectra indicates that the coordination number (7.4±1.5) and the average Np-F distance (2.26(1) Å) are consistent with the presence of the NpF8 dodecahedron. The average Np-F distance is ~0.02 Å shorter than the U-F distance in [NH 4] 4UF 8 and is a result of the actinide contraction.« less

Effect of NaF, SnF(2), and TiF(4) Toothpastes on Bovine Enamel and Dentin Erosion-Abrasion In Vitro.

PubMed

Comar, Lívia Picchi; Gomes, Marina Franciscon; Ito, Naiana; Salomão, Priscila Aranda; Grizzo, Larissa Tercília; Magalhães, Ana Carolina

2012-01-01

The aim of this study was to compare the effect of toothpastes containing TiF(4), NaF, and SnF(2) on tooth erosion-abrasion. Bovine enamel and dentin specimens were distributed into 10 groups (n = 12): experimental placebo toothpaste (no F); NaF (1450 ppm F); TiF(4) (1450 ppm F); SnF(2) (1450 ppm F); SnF(2) (1100 ppm F) + NaF (350 ppm F); TiF(4) (1100 ppm F) + NaF (350 ppm F); commercial toothpaste Pro-Health (SnF(2)-1100 ppm F + NaF-350 ppm F, Oral B); commercial toothpaste Crest (NaF-1.500 ppm F, Procter & Gamble); abrasion without toothpaste and only erosion. The erosion was performed 4 × 90 s/day (Sprite Zero). The toothpastes' slurries were applied and the specimens abraded using an electric toothbrush 2 × 15 s/day. Between the erosive and abrasive challenges, the specimens remained in artificial saliva. After 7 days, the tooth wear was evaluated using contact profilometry (μm). The experimental toothpastes with NaF, TiF(4), SnF(2), and Pro-Health showed a significant reduction in enamel wear (between 42% and 54%). Pro-Health also significantly reduced the dentin wear. The toothpastes with SnF(2)/NaF and TiF(4)/NaF showed the best results in the reduction of enamel wear (62-70%) as well as TiF(4), SnF(2), SnF(2)/NaF, and TiF(4)/NaF for dentin wear (64-79%) (P < 0.05). Therefore, the experimental toothpastes containing both conventional and metal fluoride seem to be promising in reducing tooth wear.

48 CFR 1252.231-70 - Date of incurrence of costs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... costs incurred on or after ______ in an amount not to exceed $______ that, if incurred after this... costs. 1252.231-70 Section 1252.231-70 Federal Acquisition Regulations System DEPARTMENT OF....231-70 Date of incurrence of costs. As prescribed in (TAR) 48 CFR 1231.205-32(b), insert the following...

48 CFR 231.205-19 - Insurance and indemnification.

Code of Federal Regulations, 2011 CFR

2011-10-01

... indemnification. 231.205-19 Section 231.205-19 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND... to the cost limitations in FAR 31.205-19(e), self-insurance and purchased insurance costs are subject...

48 CFR 231.205-19 - Insurance and indemnification.

Code of Federal Regulations, 2012 CFR

2012-10-01

... indemnification. 231.205-19 Section 231.205-19 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND... to the cost limitations in FAR 31.205-19(e), self-insurance and purchased insurance costs are subject...

48 CFR 231.205-19 - Insurance and indemnification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... indemnification. 231.205-19 Section 231.205-19 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND... to the cost limitations in FAR 31.205-19(e), self-insurance and purchased insurance costs are subject...

48 CFR 231.205-19 - Insurance and indemnification.

Code of Federal Regulations, 2014 CFR

2014-10-01

... indemnification. 231.205-19 Section 231.205-19 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND... to the cost limitations in FAR 31.205-19(e), self-insurance and purchased insurance costs are subject...

48 CFR 231.205-19 - Insurance and indemnification.

Code of Federal Regulations, 2013 CFR

2013-10-01

... indemnification. 231.205-19 Section 231.205-19 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND... to the cost limitations in FAR 31.205-19(e), self-insurance and purchased insurance costs are subject...

5 CFR 532.231 - Responsibilities of participating organizations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... organizations. 532.231 Section 532.231 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE... organizations. (a) The Office of Personnel Management: (1) Defines the boundaries of wage and survey areas; (2... recommendations of the national headquarters of any agency or labor organization relating to the Office of...

Nucleotide, cytogenetic and expression impact of the human chromosome 8p23.1 inversion polymorphism.

PubMed

Bosch, Nina; Morell, Marta; Ponsa, Immaculada; Mercader, Josep Maria; Armengol, Lluís; Estivill, Xavier

2009-12-14

The human chromosome 8p23.1 region contains a 3.8-4.5 Mb segment which can be found in different orientations (defined as genomic inversion) among individuals. The identification of single nucleotide polymorphisms (SNPs) tightly linked to the genomic orientation of a given region should be useful to indirectly evaluate the genotypes of large genomic orientations in the individuals. We have identified 16 SNPs, which are in linkage disequilibrium (LD) with the 8p23.1 inversion as detected by fluorescent in situ hybridization (FISH). The variability of the 8p23.1 orientation in 150 HapMap samples was predicted using this set of SNPs and was verified by FISH in a subset of samples. Four genes (NEIL2, MSRA, CTSB and BLK) were found differentially expressed (p<0.0005) according to the orientation of the 8p23.1 region. Finally, we have found variable levels of mosaicism for the orientation of the 8p23.1 as determined by FISH. By means of dense SNP genotyping of the region, haplotype-based computational analyses and FISH experiments we could infer and verify the orientation status of alleles in the 8p23.1 region by detecting two short haplotype stretches at both ends of the inverted region, which are likely the relic of the chromosome in which the original inversion occurred. Moreover, an impact of 8p23.1 inversion on gene expression levels cannot be ruled out, since four genes from this region have statistically significant different expression levels depending on the inversion status. FISH results in lymphoblastoid cell lines suggest the presence of mosaicism regarding the 8p23.1 inversion.

Polar Cap Pits

NASA Technical Reports Server (NTRS)

2005-01-01

17 August 2005 This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows kidney bean-shaped pits, and other pits, formed by erosion in a landscape of frozen carbon dioxide. This images shows one of about a dozen different patterns that are common in various locations across the martian south polar residual cap, an area that has been receiving intense scrutiny by the MGS MOC this year, because it is visible on every orbit and in daylight for most of 2005.

Location near: 86.9oS, 6.9oW Image width: width: 3 km (1.9 mi) Illumination from: upper left Season: Southern Spring

Associations between active trachoma and community intervention with Antibiotics, Facial cleanliness, and Environmental improvement (A,F,E).

PubMed

Ngondi, Jeremiah; Matthews, Fiona; Reacher, Mark; Baba, Samson; Brayne, Carol; Emerson, Paul

2008-04-30

Surgery, Antibiotics, Facial cleanliness and Environmental improvement (SAFE) are advocated by the World Health Organization (WHO) for trachoma control. However, few studies have evaluated the complete SAFE strategy, and of these, none have investigated the associations of Antibiotics, Facial cleanliness, and Environmental improvement (A,F,E) interventions and active trachoma. We aimed to investigate associations between active trachoma and A,F,E interventions in communities in Southern Sudan. Surveys were undertaken in four districts after 3 years of implementation of the SAFE strategy. Children aged 1-9 years were examined for trachoma and uptake of SAFE assessed through interviews and observations. Using ordinal logistic regression, associations between signs of active trachoma and A,F,E interventions were explored. Trachomatous inflammation-intense (TI) was considered more severe than trachomatous inflammation-follicular (TF). A total of 1,712 children from 25 clusters (villages) were included in the analysis. Overall uptake of A,F,E interventions was: 53.0% of the eligible children had received at least one treatment with azithromycin; 62.4% children had a clean face on examination; 72.5% households reported washing faces of children two or more times a day; 73.1% households had received health education; 44.4% of households had water accessible within 30 minutes; and 6.3% households had pit latrines. Adjusting for age, sex, and district baseline prevalence of active trachoma, factors independently associated with reduced odds of a more severe active trachoma sign were: receiving three treatments with azithromycin (odds ratio [OR] = 0.1; 95% confidence interval [CI] 0.0-0.4); clean face (OR = 0.3; 95% CI 0.2-0.4); washing faces of children three or more times daily (OR = 0.4; 95% CI 0.3-0.7); and presence and use of a pit latrine in the household (OR = 0.4; 95% CI 0.2-0.9). Analysis of associations between the A,F,E components of the SAFE strategy and active

48 CFR 1352.231-71 - Duplication of effort.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Duplication of effort. 1352.231-71 Section 1352.231-71 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE CLAUSES... benefit of the Government, and not incidental to any other work, pursuit, research, or purpose of the...

27 CFR 19.231 - Accounting for bond coverage.

Code of Federal Regulations, 2011 CFR

2011-04-01

.... If the balance of the bond account reaches zero, the proprietor may no longer defer tax payments for... coverage. 19.231 Section 19.231 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Distilled Spirits Taxes Rules for...

Investigating pitting in X65 carbon steel using potentiostatic polarisation

NASA Astrophysics Data System (ADS)

Mohammed, Sikiru; Hua, Yong; Barker, R.; Neville, A.

2017-11-01

Although pitting corrosion in passive materials is generally well understood, the growth of surface pits in actively-corroding materials has received much less attention to date and remains poorly understood. One of the key challenges which exists is repeatedly and reliably generating surface pits in a practical time-frame in the absence of deformation and/or residual stress so that studies on pit propagation and healing can be performed. Another pertinent issue is how to evaluate pitting while addressing general corrosion in low carbon steel. In this work, potentiostatic polarisation was employed to induce corrosion pits (free from deformation or residual stress) on actively corroding X65 carbon steel. The influence of applied potential (50 mV, 100 mV and 150 mV vs open circuit potential) was investigated over 24 h in a CO2-saturated, 3.5 wt.% NaCl solution at 30 °C and pH 3.8. Scanning electron microscopy (SEM) was utilised to examine pits, while surface profilometry was conducted to measure pit depth as a function of applied potential over the range considered. Analyses of light pitting (up to 120 μm) revealed that pit depth increased linearly with increase in applied potential. This paper relates total pit volume (measured using white light interferometry) to dissipated charge or total mass loss (using the current response for potentiostatic polarisation in conjunction with Faraday's law). By controlling the potential of the surface (anodic) the extent of pitting and general corrosion could be controlled. This allowed pits to be evaluated for their ability to continue to propagate after the potentiostatic technique was employed. Linear growth from a depth of 70 μm at pH 3.8, 80 °C was demonstrated. The technique offers promise for the study of inhibition of pitting.

33 CFR 110.231 - Ketchikan Harbor, Alaska, Large Passenger Vessel Anchorage.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Passenger Vessel Anchorage. 110.231 Section 110.231 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.231 Ketchikan Harbor, Alaska, Large Passenger Vessel Anchorage. (a) The anchorage grounds. Ketchikan Harbor, Alaska, Large...

33 CFR 110.231 - Ketchikan Harbor, Alaska, Large Passenger Vessel Anchorage.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Passenger Vessel Anchorage. 110.231 Section 110.231 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.231 Ketchikan Harbor, Alaska, Large Passenger Vessel Anchorage. (a) The anchorage grounds. Ketchikan Harbor, Alaska, Large...

33 CFR 110.231 - Ketchikan Harbor, Alaska, Large Passenger Vessel Anchorage.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Passenger Vessel Anchorage. 110.231 Section 110.231 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.231 Ketchikan Harbor, Alaska, Large Passenger Vessel Anchorage. (a) The anchorage grounds. Ketchikan Harbor, Alaska, Large...

33 CFR 110.231 - Ketchikan Harbor, Alaska, Large Passenger Vessel Anchorage.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Passenger Vessel Anchorage. 110.231 Section 110.231 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.231 Ketchikan Harbor, Alaska, Large Passenger Vessel Anchorage. (a) The anchorage grounds. Ketchikan Harbor, Alaska, Large...

33 CFR 110.231 - Ketchikan Harbor, Alaska, Large Passenger Vessel Anchorage.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Passenger Vessel Anchorage. 110.231 Section 110.231 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.231 Ketchikan Harbor, Alaska, Large Passenger Vessel Anchorage. (a) The anchorage grounds. Ketchikan Harbor, Alaska, Large...

Study on the Accident-causing of Foundation Pit Engineering

NASA Astrophysics Data System (ADS)

Shuicheng, Tian; Xinyue, Zhang; Pengfei, Yang; Longgang, Chen

2018-05-01

With the development of high-rise buildings and underground space, a large number of foundation pit projects have occurred. Frequent accidents of it cause great losses to the society, how to reduce the frequency of pit accidents has become one of the most urgent problems to be solved. Therefore, analysing the influencing factors of foundation pit engineering accidents and studying the causes of foundation pit accidents, which of great significance for improving the safety management level of foundation pit engineering and reducing the incidence of foundation pit accidents. Firstly, based on literature review and questionnaires, this paper selected construction management, survey, design, construction, supervision and monitoring as research factors, we used the AHP method and the Dematel method to analyze the weights of various influencing factors to screen indicators to determine the ultimate system of accidents caused by foundation pit accidents; Secondly, SPSS 21.0 software was used to test the reliability and validity of the recovered questionnaire data. AMOS 7.0 software was used to fit, evaluate, and explain the set model; Finally, this paper analysed the influencing factors of foundation pit engineering accidents, corresponding management countermeasures and suggestions were put forward.

Nobody’s perfect: can irregularities in pit structure influence vulnerability to cavitation?

PubMed Central

Plavcová, Lenka; Jansen, Steven; Klepsch, Matthias; Hacke, Uwe G.

2013-01-01

Recent studies have suggested that species-specific pit properties such as pit membrane thickness, pit membrane porosity, torus-to-aperture diameter ratio and pit chamber depth influence xylem vulnerability to cavitation. Despite the indisputable importance of using mean pit characteristics, considerable variability in pit structure within a single species or even within a single pit field should be acknowledged. According to the rare pit hypothesis, a single pit that is more air-permeable than many neighboring pits is sufficient to allow air-seeding. Therefore, any irregularities or morphological abnormalities in pit structure allowing air-seeding should be associated with increased vulnerability to cavitation. Considering the currently proposed models of air-seeding, pit features such as rare, large pores in the pit membrane, torus extensions, and plasmodesmatal pores in a torus can represent potential glitches. These aberrations in pit structure could either result from inherent developmental flaws, or from damage caused to the pit membrane by chemical and physical agents. This suggests the existence of interesting feedbacks between abiotic and biotic stresses in xylem physiology. PMID:24273549

Disruption of Mouse Cytochrome P450 4f14 (Cyp4f14 Gene) Causes Severe Perturbations in Vitamin E Metabolism*

PubMed Central

Bardowell, Sabrina A.; Duan, Faping; Manor, Danny; Swanson, Joy E.; Parker, Robert S.

2012-01-01

Vitamin E is a family of naturally occurring and structurally related lipophilic antioxidants, one of which, α-tocopherol (α-TOH), selectively accumulates in vertebrate tissues. The ω-hydroxylase cytochrome P450–4F2 (CYP4F2) is the only human enzyme shown to metabolize vitamin E. Using cDNA cloning, cell culture expression, and activity assays, we identified Cyp4f14 as a functional murine ortholog of CYP4F2. We then investigated the effect of Cyp4f14 deletion on vitamin E metabolism and status in vivo. Cyp4f14-null mice exhibited substrate-specific reductions in liver microsomal vitamin E-ω-hydroxylase activity ranging from 93% (γ-TOH) to 48% (γ-tocotrienol). In vivo data obtained from metabolic cage studies showed whole-body reductions in metabolism of γ-TOH of 90% and of 68% for δ- and α-TOH. This metabolic deficit in Cyp4f14−/− mice was partially offset by increased fecal excretion of nonmetabolized tocopherols and of novel ω-1- and ω-2-hydroxytocopherols. 12′-OH-γ-TOH represented 41% of whole-body production of γ-TOH metabolites in Cyp4f14−/− mice fed a soybean oil diet. Despite these counterbalancing mechanisms, Cyp4f14-null mice fed this diet for 6 weeks hyper-accumulated γ-TOH (2-fold increase over wild-type littermates) in all tissues and appeared normal. We conclude that CYP4F14 is the major but not the only vitamin E-ω-hydroxylase in mice. Its disruption significantly impairs whole-body vitamin E metabolism and alters the widely conserved phenotype of preferential tissue deposition of α-TOH. This model animal and its derivatives will be valuable in determining the biological actions of specific tocopherols and tocotrienols in vivo. PMID:22665481

Nuclear Data Sheets for A = 231

DOE Office of Scientific and Technical Information (OSTI.GOV)

Browne, E.; Tuli, J.K.

Spectroscopic data for all nuclei with mass number A=231 have been evaluated, and the corresponding level schemes from radioactive decay and reaction studies are presented. Highlights of this evaluation include: A new interpretation of γ–ray spectroscopic results measured with the GAMMASPHERE spectrometer (2002AbZV, 2000JaZY, 1999Br17) has established the level structure of the ground state rotational band 1/2[400] up to spin/parity 45/2+ in {sup 231}Ac. Precise measurements of energies and cross sections of scattered tritons from the {sup 232}Th(d,t) reaction has produced or confirmed the identification of several rotational bands in {sup 231}Th. The alpha hindrance factors (HF) presented in thismore » evaluation were calculated using values of the radius parameter (r{sub 0}) interpolated from those for even–even adjacent nuclei given in 1998Ak04. The Limitation of Relative Statistical Weight (LWM) method (1985ZiZY) has been used for discrepant data throughout this evaluation.« less

Persistent pit viper envenomation in a cat.

PubMed

Yankin, Igor; Schaer, Michael; Johnson, Matthew; Meland, Tessa; Londoño, Leonel A

2017-01-01

A 4-year-old female spayed, indoor/outdoor domestic mediumhair cat presented with multiple bleeding puncture wounds and hemorrhagic shock. The cat was diagnosed with suspected pit viper envenomation based on the location and appearance of the bite wounds, as well as the presence of severe coagulopathy with prolonged activated coagulation time (762 s), which responded to antivenom administration. The clinical course of the cat was unique owing to the prolonged clinical signs of envenomation that appeared as intermittent coagulopathy and hemorrhage over a 2 week period. Five vials of antivenom were administered and three units of packed red blood cells were transfused over a 7 day period. The cat made a complete recovery with cessation of hemorrhage and normalization of clotting times. This is the first report of persistent pit viper venom-induced coagulopathy in the feline veterinary literature.

49 CFR 231.31 - Drawbars for freight cars; standard height.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Drawbars for freight cars; standard height. 231.31... cars; standard height. (a) Except on cars specified in paragraph (b) of this section— (1) On standard gage (561/2-inch gage) railroads, the maximum height of drawbars for freight cars (measured...

49 CFR 231.31 - Drawbars for freight cars; standard height.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Drawbars for freight cars; standard height. 231.31... cars; standard height. (a) Except on cars specified in paragraph (b) of this section— (1) On standard gage (561/2-inch gage) railroads, the maximum height of drawbars for freight cars (measured...

49 CFR 231.31 - Drawbars for freight cars; standard height.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Drawbars for freight cars; standard height. 231.31... cars; standard height. (a) Except on cars specified in paragraph (b) of this section— (1) On standard gage (561/2-inch gage) railroads, the maximum height of drawbars for freight cars (measured...

49 CFR 231.31 - Drawbars for freight cars; standard height.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Drawbars for freight cars; standard height. 231.31... cars; standard height. (a) Except on cars specified in paragraph (b) of this section— (1) On standard gage (561/2-inch gage) railroads, the maximum height of drawbars for freight cars (measured...

49 CFR 231.31 - Drawbars for freight cars; standard height.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Drawbars for freight cars; standard height. 231.31... cars; standard height. (a) Except on cars specified in paragraph (b) of this section— (1) On standard gage (561/2-inch gage) railroads, the maximum height of drawbars for freight cars (measured...

Alanine and glycine conjugates of (2S,4R)-4-[18F]fluoroglutamine for tumor imaging.

PubMed

Zha, Zhihao; Ploessl, Karl; Lieberman, Brian P; Wang, Limin; Kung, Hank F

2018-05-01

Glutamine is an essential source of energy, metabolic substrates, and building block for supporting tumor proliferation. Previously, (2S,4R)-4-[ 18 F]fluoroglutamine (4F-Gln) was reported as a glutamine-related metabolic imaging agent. To improve the in vivo kinetics of this radiotracer, two new dipeptides, [ 18 F]Gly-(2S,4R)4-fluoroglutamine (Gly-4F-Gln) and [ 18 F]Ala-(2S,4R)4-fluoroglutamine (Ala-4F-Gln) were investigated. Radiolabeling was performed via 2-steps 18 F-fluorination. Cell uptake studies of Gly-4F-Gln and Ala-4F-Gln were investigated in 9 L cell lines. In vitro and in vivo metabolism studies were carried out in Fisher 344 rats. Biodistribution and microPET imaging studies were performed in 9 L tumor-bearing rats. In vitro incubation of these [ 18 F]dipeptides in rat and human blood showed a rapid conversion to (2S,4R)-4-[ 18 F]fluoroglutamine (t 1/2  = 2.3 and 0.2 min for [ 18 F]Gly-4F-Gln and [ 18 F]Ala-4F-Gln, respectively for human blood). Biodistribution and PET imaging in Fisher 344 rats bearing 9 L tumor xenografts showed that these dipeptides rapidly localized in the tumors, comparable to that of (2S,4R)-4-[ 18 F]fluoroglutamine (4F-Gln). The results support that these dipeptides, [ 18 F]Gly-4F-Gln and [ 18 F]Ala-4F-Gln, are prodrugs, which hydrolyze in the blood after an iv injection. They appear to be selectively taken up and trapped by tumor tissue in vivo. The dipeptide, [ 18 F]Ala-4F-Gln, may be suitable as a PET tracer for imaging glutaminolysis in tumors. Copyright © 2018 Elsevier Inc. All rights reserved.

Observations of 231Pa/ 235U disequilibrium in volcanic rocks

NASA Astrophysics Data System (ADS)

Pickett, David A.; Murrell, Michael T.

1997-04-01

We present here the first survey of ( 231Pa/ 235U) ratios in volcanic rocks; such measurements are made possible by new mass spectrometric techniques. The data place new constraints on the timing and extent of magma source and evolutionary processes, particularly due to the sensitivity of the 231Pa- 235U pair and its intermediate time scale ( 231Pat 1/2 = 33 ky). ( 231Pa/ 235U) is found to vary widely, from 0.2 in carbonatites to 1.1-2.9 in basalts and 0.9-2.2 in arcs. Substantial Pa enrichment is nearly ubiquitous, suggestive of the relative incompatibility of Pa, qualitatively consistent with available partitioning data. The level of 231Pa- 235U disequilibrium typically far exceeds that of 230Th- 238U and is comparable to 226Ra- 230Th. The high ( 231Pa/ 235U) ratios in MORB and other basalts reflect a large degree of discrimination between two incompatible elements, posing challenges for modelling of melt generation and migration. Fundamental differences in ( 231Pa/ 235U) among different basaltic environments are likely related to contrasts in melting zone conditions (e.g., melting rate). Strong ( 231Pa/ 235U) disequilibria in continental basalts, for which ( 230Th/ 238U) disequilibria are small or absent, demonstrate that Pa-U fractionation is possible in both garnet and spinel mantle stability fields. In arcs, correlation of ( 231Pa/ 235U) and ( 230Th/ 238U) is consistent with U enrichment via slab-derived fluids, a process which is additional to the still dominant Pa enrichment. An important new constraint is provided by the observation that the near-equilibrium ( 230Th/ 238U) common to arcs and continental basalts is not typically accompanied by near-equilibrium ( 231Pa/ 235U), arguing against the influence of long magma history, crustal material, or equilibrium mantle sources in affecting decay-series ratios. Small sample sets from two silicic centers illustrate: (1) recent, rapid U enrichment in the magma chamber (El Chichón); and (2) the failure of

CLEC4F Is an Inducible C-Type Lectin in F4/80-Positive Cells and Is Involved in Alpha-Galactosylceramide Presentation in Liver

PubMed Central

Yang, Chih-Ya; Chen, Jiun-Bo; Tsai, Ting-Fen; Tsai, Yi-Chen; Tsai, Ching-Yen; Liang, Pi-Hui; Hsu, Tsui-Ling; Wu, Chung-Yi; Netea, Mihai G.; Wong, Chi-Huey; Hsieh, Shie-Liang

2013-01-01

CLEC4F, a member of C-type lectin, was first purified from rat liver extract with high binding affinity to fucose, galactose (Gal), N-acetylgalactosamine (GalNAc), and un-sialylated glucosphingolipids with GalNAc or Gal terminus. However, the biological functions of CLEC4F have not been elucidated. To address this question, we examined the expression and distribution of murine CLEC4F, determined its binding specificity by glycan array, and investigated its function using CLEC4F knockout (Clec4f−/−) mice. We found that CLEC4F is a heavily glycosylated membrane protein co-expressed with F4/80 on Kupffer cells. In contrast to F4/80, CLEC4F is detectable in fetal livers at embryonic day 11.5 (E11.5) but not in yolk sac, suggesting the expression of CLEC4F is induced as cells migrate from yolk cells to the liver. Even though CLEC4F is not detectable in tissues outside liver, both residential Kupffer cells and infiltrating mononuclear cells surrounding liver abscesses are CLEC4F-positive upon Listeria monocytogenes (L. monocytogenes) infection. While CLEC4F has strong binding to Gal and GalNAc, terminal fucosylation inhibits CLEC4F recognition to several glycans such as Fucosyl GM1, Globo H, Bb3∼4 and other fucosyl-glycans. Moreover, CLEC4F interacts with alpha-galactosylceramide (α-GalCer) in a calcium-dependent manner and participates in the presentation of α-GalCer to natural killer T (NKT) cells. This suggests that CLEC4F is a C-type lectin with diverse binding specificity expressed on residential Kupffer cells and infiltrating monocytes in the liver, and may play an important role to modulate glycolipids presentation on Kupffer cells. PMID:23762286

14 CFR 25.231 - Longitudinal stability and control.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Longitudinal stability and control. 25.231... Characteristics § 25.231 Longitudinal stability and control. (a) Landplanes may have no uncontrollable tendency to... on concrete, to maintain any attitude up to thrust line level, at 75 percent of V SR 1. (b) For...

14 CFR 25.231 - Longitudinal stability and control.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Longitudinal stability and control. 25.231... Characteristics § 25.231 Longitudinal stability and control. (a) Landplanes may have no uncontrollable tendency to... on concrete, to maintain any attitude up to thrust line level, at 75 percent of V SR 1. (b) For...

14 CFR 25.231 - Longitudinal stability and control.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Longitudinal stability and control. 25.231... Characteristics § 25.231 Longitudinal stability and control. (a) Landplanes may have no uncontrollable tendency to... on concrete, to maintain any attitude up to thrust line level, at 75 percent of V SR 1. (b) For...

14 CFR 25.231 - Longitudinal stability and control.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Longitudinal stability and control. 25.231... Characteristics § 25.231 Longitudinal stability and control. (a) Landplanes may have no uncontrollable tendency to... on concrete, to maintain any attitude up to thrust line level, at 75 percent of V SR 1. (b) For...

Transcytosis of F4 fimbriae by villous and dome epithelia in F4-receptor positive pigs supports importance of receptor-dependent endocytosis in oral immunization strategies.

PubMed

Snoeck, Veerle; Van den Broeck, Wim; De Colvenaer, Veerle; Verdonck, Frank; Goddeeris, Bruno; Cox, Eric