Sample records for sair da vitrine

  1. SAIRS” — Scalable Amtec Integrated Reactor space power System

    Microsoft Academic Search

    Mohamed S. El-Genk; Jean-Michel P. Tournier

    2004-01-01

    Conceptual Designs of three, 111 kWe, Scalable AMTEC Integrated Reactor Space Power Systems (SAIRS) are developed. These systems employ fast-spectrum reactors cooled by sodium (Na) heat pipes, C-C armored, potassium (K) heat pipes radiators, and Alkali Metal Thermal-To-Electric Conversion (AMTEC) units. The reactor Na- and the radiator K-heat pipes operate at

  2. Aimé Césaire: a warrior in search of beauty

    Microsoft Academic Search

    Bernadette Cailler

    2010-01-01

    This essay examines several tributes that appeared following Césaire's death on 17 April 2008, namely, those expressed by three major Martinican creative writers and thinkers, Patrick Chamoiseau, Edouard Glissant, and Raphaël Confiant. References to Guadeloupean writers Ernest Pépin's and Daniel Maximin's homages are also included. Reminding the reader that the legacy of Césaire the poet is immense, notwithstanding the disagreements

  3. Tectonic, eustatic and climatic significance of raised beaches of Val de Saire, Cotentin, Normandy, France

    NASA Astrophysics Data System (ADS)

    Coutard, Sylvie; Lautridou, Jean-Pierre; Rhodes, Ed; Clet, Martine

    2006-03-01

    Detailed mapping, morphostratigraphical and geochronological analyses were undertaken in the Val de Saire, Cotentin, Normandy, northern France. These studies have identified a series of Middle and Upper Pleistocene-age deposits overlying four wave-cut platforms (PF IV-PF I), which can be associated with temperate high sea-level events and equated with MIS 11, 9, 7 and MI Substage 5e. A sea-level stand recorded at -20 m NGF at the La Mondrée site seems to correspond to MI Substage 5c or 5a. The completeness of the Val de Saire record, and particularly the width of platform IV (MIS 11), has so far no equivalent on the south coast of the English Channel. This study provides contribution to an understanding of the impact of the interglacial-glacial cycles in a coastal intraplate situation. The cyclicity of the morphogenesis is explained by interaction between eustatic variations and strongly expressed activity of slow uplift (ca 60 mm/kyr through the Middle Pleistocene). Several OSL dates from the gravel to sand sequence of the Eemian-Weichselian cycle indicate that these deposits represent the marine regression of the end of the Last Interglacial.

  4. spxA2, encoding a regulator of stress resistance in Bacillus anthracis, is controlled by SaiR, a new member of the Rrf2 protein family.

    PubMed

    Nakano, Michiko M; Kominos-Marvell, Wren; Sane, Bhagyashree; Nader, Yaldah Mohammad; Barendt, Skye M; Jones, Marcus B; Zuber, Peter

    2014-11-01

    Spx, a member of the ArsC (arsenate reductase) protein family, is conserved in Gram-positive bacteria, and interacts with RNA polymerase to activate transcription in response to toxic oxidants. In Bacillus anthracis str. Sterne, resistance to oxidative stress requires the activity of two paralogues, SpxA1 and SpxA2. Suppressor mutations were identified in spxA1 mutant cells that conferred resistance to hydrogen peroxide. The mutations generated null alleles of the saiR gene and resulted in elevated spxA2 transcription. The saiR gene resides in the spxA2 operon and encodes a member of the Rrf2 family of transcriptional repressors. Derepression of spxA2 in a saiR mutant required SpxA2, indicating an autoregulatory mechanism of spxA2 control. Reconstruction of SaiR-dependent control of spxA2 was accomplished in Bacillus subtilis, where deletion analysis uncovered two cis-elements within the spxA2 regulatory region that are required for repression. Mutations to one of the sequences of dyad symmetry substantially reduced SaiR binding and SaiR-dependent repression of transcription from the spxA2 promoter in vitro. Previous studies have shown that spxA2 is one of the most highly induced genes in a macrophage infected with B. anthracis. The work reported herein uncovered a key regulator, SaiR, of the Spx system of stress response control. PMID:25231235

  5. External Analysis and Planning. SAIR Conference Paper.

    ERIC Educational Resources Information Center

    Ruddock, Maryann Steele; Rossy, Kenneth

    The potential use of the preferred imaging technique by the Office of Planning and Analysis of the University of Texas System is discussed, along with the use of environmental scanning. Preferred imaging is used to get people thinking about the future and how it relates to the external environment and the planning process. Preferred imaging…

  6. Interest in Evening Courses: Survey Analysis. SAIR Conference Paper.

    ERIC Educational Resources Information Center

    Bottomley, Wayne N.; And Others

    Student interest in increased evening courses at Daytona Beach Campus of Embry-Riddle Aeronautical University (ERAU) was investigated. The proportion of students employed while attending ERAU and student attitudes concerning evening or Saturday courses were also determined. Of the 3,312 students preregistered for fall 1982, 862 completed a…

  7. VITRINE: a next generation low Earth orbit exposure facility for astrochemistry and exobiology

    NASA Astrophysics Data System (ADS)

    Cottin, Hervé; Coll, P.; Ehrenfreund, P.; Baratta, G. A.; Bénilan, Y.; Bertrand, M.; Borget, F.; Buch, A.; Chieavassa, T.; Couturier, I.; Dartois, E.; D'Hendecourt, L.; Duvernay, F.; Fray, N.; Gazeau, M. C.; Leach, S.; Mattioda, A.; Piétri, N.; Quinn, R.; Raulin, F.; Ricco, A. J.; Santos, O.; Strazzulla, G.; Szopa, C.; Theulé, P.; Westall, F.; Villenave, M.; Lefevre, F.; Belasic, M.; Chazalnoel, P.; Viso, M.

    The study of the evolution of organic matter submitted to space conditions, and more specifi-cally to solar photons in the vacuum ultraviolet range (120-200 nm) has been undertaken in low Earth Orbit since the 90's, and implemented on various space platforms. The most recent facil-ities of exposition are BIOPAN outside Russian automatic capsules FOTON, and EXPOSE-E -R on the International Space Station. They allow the photolysis of many different samples simultaneously, and provide us with valuable data about the formation and evolution of organic matter in the Solar System (meteorites, comets, Titan atmosphere, Martian surface. . . ) and in the Interstellar Medium. They have been used by European teams in the recent past (OR-GANIC on BIOPAN V-FOTON M2, UVolution on BIOPAN VI-FOTON M3 and PROCESS on EXPOSE-E), and some experiments are currently in progress outside of the ISS: AMINO and ORGANICS on EXPOSE-R). These existing tools are very valuable; however they have significant limitations downscaling their capabilities: 1) These facilities are passively placed outside Earth orbiting space modules, with no Sun pointing device. This results in a low integrated time of actual exposition to the Sun (about 10 percents of total time in space). 2) It is not possible to follow the evolution of the samples during its exposition time in space. 3) The temperature of the samples is not controlled. It is impossible to implement experiments on sample at very low temperature (pure ice, or mixtures at about 10k). That kind of experi-ments is very current in the laboratory to study interstellar and cometary ices, or the evolution of the surface of icy satellites of giant planets. Therefore we are proposing the development of a new space instrument, for long duration expositions in space (> 1 yr) with the following features: -Control of temperature, and capacity to deal with samples at very low T. -Sun pointing device or equivalent mechanism (heliostat) in order to optimize the ratio: exposition time to UV/duration of stay in space. -Analytical tools in order to follow the evolution of the composition of the samples during the whole duration of the experiment: non destructive analyses by infrared and ultraviolet spectroscopy, and destructive analysis by gas chromatography and/or mass spectroscopy. Some of the samples could be replaced in flight to repeat the experiment. -Telemetry to send the data to Earth. This project is supported by CNES through an action of research and development. Such an instrument could be conveniently accommodated outside the International Space Station.

  8. Producing "Service to Non-Major" Reports Without an ICLM via NCHEMS. SAIR Conference Paper.

    ERIC Educational Resources Information Center

    McCord, Michael T.; Ingle, Robert

    The procedures for producing a report on departmental service to nonmajors are described in detail. The objective was to provide information for decision-making needs without reliance on the standardized pre-packaged models. An alternative to the Induced Course Load Matrix (ICLM) of the Resource Requirements Prediction Model (RRPM) package of the…

  9. Strategic Planning vs. Disjointed Incrementalism: An Institutional Research Perspective. SAIR Conference Paper.

    ERIC Educational Resources Information Center

    Jean, Paul M.; And Others

    Strategic planning in higher education is discussed from the perspective of institutional research. Attention is directed to: institutional mission, institutional assessment, institutional leadership, environmental assessment, market analysis, and competitive position. Strategic planning merges incrementalism, which focuses on flexibility,…

  10. On Slavery, Césaire, and Relating to the World: An Interview with Patrick Chamoiseau

    Microsoft Academic Search

    2009-01-01

    In an interview which took place in the Maison Française, Oxford, on 10 May 2008, the day instituted by the Chirac government to commemorate the crime of slavery, Patrick Chamoiseau discusses his attempts to raise consciousness of slavery among young Antilleans. He reflects on his relationship with a number of Caribbean writers, including Edouard Glissant, Derek Walcott and the recently-deceased

  11. A Comparison of Procedures for Establishing Peer Groups. SAIR Conference Paper.

    ERIC Educational Resources Information Center

    Teeter, Deborah J.; Christal, Melodie E.

    This paper compares two methodologies for selecting peer institutions used by the National Center for Higher Education Management Systems (NCHEMS) and by the State of Kansas. The University of Kansas was used as a test institution to compare the NCHEMS and Kansas methodologies. Attention is directed to differences in results, the impact of data…

  12. Project DaVinci

    NASA Astrophysics Data System (ADS)

    Winarsky, Norman; Alexander, Joanna R.

    1991-06-01

    This paper describes one of the first projects -- Project Da Vinci -- tasked by the NIDL. DaVinci is a long-term project which will require research and development in diverse areas including data fusion, multi-dimensional model-based rendering, multi-dimensional data visualization, and database browsing. It is designed to have broad impact across the government, industrial, medical and academic communities. Part of the charter is to gain the support of the best resources available in these areas.

  13. O Paradoxo do Discurso da Responsabilidade Social da Empresa : Modismo ou Anlise Consistente da Atualidade?

    E-print Network

    Paris-Sud XI, Université de

    1 O Paradoxo do Discurso da Responsabilidade Social da Empresa : Modismo ou Análise Consistente daApresentação Este artigo discute o conceito de Responsabilidade Social da Empresa (RSE) como um tema muitas a Responsabilidade Social. Mostraremos através deste ensaio como vivemos em um mundo em crise, baseado na mídia e na

  14. A PRÁTICA DA VEGETOTERAPIA CARACTEROANALÍTICA

    Microsoft Academic Search

    José Henrique Volpi; Maria Beatriz de Paula

    Foi o trabalho sistemático com a técnica da análise do caráter que levou Reich a descobrir que os distúrbios psico-emocionais apresentam como equivalente somático, a couraça muscular. Couraças são tensões que se formam ao longo da vida, cuja função é proteger o indivíduo (ego) de experiências dolorosas e ameaçadoras. Inclui tensão ou flacidez crônicas da musculatura esquelética que são resultados

  15. [da Vinci surgical system].

    PubMed

    Watanabe, Gou; Ishikawa, Norihiro

    2014-07-01

    The da Vinci surgical system was developed by Intuitive Surgical Inc. in the United States as an endoscopic surgical device to assist remote control surgeries. In 1998, the Da Vinci system was first used for cardiothoracic procedures. Currently a combination of robot-assisted internal thoracic artery harvest together with coronary artery bypass grafting (CABG) through a mini-incision (ThoraCAB) or totally endoscopic procedures including anastomoses under robotic assistance (TECAB) are being conducted for the treatment of coronary artery diseases. With the recent advances in catheter interventions, hybrid procedures combining catheter intervention with ThoraCAB or TECAB are anticipated in the future.On the other hand, with the decrease in number of coronary artery bypass surgeries, the share of valvular surgeries is expected to increase in the future. Among them, mitral valvuloplasty for mitral regurgitation is anticipated to be conducted mainly by low-invasive procedures, represented by minimally invasive cardiac surgery( MICS) and robot-assisted surgery. Apart from the intrinsic good surgical view, robotic-assisted systems offer additional advantages of the availability of an amplified view and the easy to observe the mitral valve in the physiological position. Thus, robotic surgical surgeries that make complicated procedures easier are expected to accomplish further developments in the future. Furthermore, while the number of surgeries for atrial septal defects has decreased dramatically following the widespread use of Amplatzer septal occluder, robotic surgery may become a good indication for cases in which the Amplatzer device is not indicated. In Japan, clinical trial of the da Vinci robotic system for heart surgeries has been completed. Statutory approval of the da Vinci system for mitral regurgitation and atrial septal defects is anticipated in the next few years. PMID:25138939

  16. Informativo Ano 1 n 02 Agosto/2013 Lanamento da pedra fundamental da sede da OTCA

    E-print Network

    região e reduzir as assimetrias entre os Países Membros (Brasil, Bolívia, Colômbia, Equador, Peru japoneses e representantes da JICA (Japan International Cooperantion Agency) no Brasil. O objetivo da missão era mostrar aos professores de escolas japonesas informações sobre o Brasil e principalmente sobre os

  17. MINISTRIO DA EDUCAAO UNIVERSIDADE FEDERAL DO PARAN

    E-print Network

    Paraná, Universidade Federal do

    -graduaçso em Direito Portaria n.O 02612013-PPGD O Coordenador do Programa de Pós-graduação em Direito da Faculdade de Direito da Universidade Federal do Parana, no uso de suas atribuiçóes legais e regimentais, ad professor substituto. Coordenação do Programa de Pós-graduação em Direito da Faculdade de Direito da

  18. Avaliação dos efeitos das modificações da cobertura da terra na disponibilidade hídrica da bacia hidrográfica de Pimenta Bueno, Rondônia

    Microsoft Academic Search

    Tatiane E. Checchia; Thiago Bortoleto Rodrigues; Paulo Henrique Schröder; Ana Cristina; Strava Correa

    RESUMO --- A bacia hidrográfica de Pimenta Bueno (bacia Amazônica) tem sofrido intensa modificações da cobertura da terra nos últimos 20 anos (1986-2006). O objetivo deste trabalho foi avaliar estas modificações sobre a disponibilidade hídrica da bacia. Constatou-se que neste período houve um incremento de quase 300% na substituição das áreas florestais principalmente por atividades agropecuárias. A precipitação média anual

  19. PLANO ESTRATXICO DA UDC PLANO OPERATIVO ANUAL

    E-print Network

    Fraguela, Basilio B.

    .1. Fomento da cultura da calidade o O orzamento do Centro Universitario de Formación e Innovación Educativa na nova plataforma virtual baseada en Moodle, realizados a demanda de cada centro e nas súas propias

  20. MINISTRIO DA EDUCAO UNIVERSIDADE FEDERAL DO PARAN

    E-print Network

    Paraná, Universidade Federal do

    CARVALHO CUTTI 1º SIMONE DA SILVA SORIA MEDINA CEG207 - GEOMETRIA DESCRITIVA 2491 RICARDO KAZUNORI IKEDAI 1 MEDINA CD027 - EXPRESSÃO GRÁFICA I 2487 BETINA LEITÃO MEHL 2º SIMONE DA SILVA SORIA MEDINA CD027

  1. Leonardo da Vinci and the Downburst.

    NASA Astrophysics Data System (ADS)

    Gedzelman, Stanley David

    1990-05-01

    Evidence from the drawings, experiments, and writings of Leonardo da Vinci are presented to demonstrate that da Vinci recognized and, possibly, discovered the downburst and understood its associated airflow. Other early references to vortex flows resembling downbursts are mentioned.

  2. AGUARDANDO HOMOLOGAO MINISTRIO DA EDUCAO

    E-print Network

    Maier, Rudolf Richard

    horária mínima do curso de Pedagogia em função do parecer nº 3/2006 CNE/CP, que trata das Diretrizes que à época da edição do Parecer, objeto desta análise, o curso de Pedagogia era desenvolvido sob Diretrizes Curriculares Nacionais para o Curso de Pedagogia, licenciaturas. Por esse motivo, é necessário

  3. ANÁLISE DA CADEIA PRODUTIVA DA CAPRINO-OVINOCULTURA EM GARANHUNS

    Microsoft Academic Search

    Daniela Moreira de Carvalho; Jalmir Pinheiro De Souza

    2008-01-01

    A caprino-ovinocultura na região Nordeste tem grande importância tanto econômica quanto social, devido ao fato dos animais terem uma boa adaptação ao clima e a alimentação, muitas vezes escassa, disponível na região. A compreensão das cadeias produtivas locais permite a proposição de melhorias no setor a fim de torná-lo mais eficiente. Na caprino-ovinocultura a eficiência ocorre através da oferta aos

  4. The major histocompatibility complex genes impact pain response in DA and DA.1U rats.

    PubMed

    Guo, Yuan; Yao, Fan-Rong; Cao, Dong-Yuan; Li, Li; Wang, Hui-Sheng; Xie, Wen; Zhao, Yan

    2015-08-01

    Our recent studies have shown that the difference in basal pain sensitivity to mechanical and thermal stimulation between Dark-Agouti (DA) rats and a novel congenic DA.1U rats is major histocompatibility complex (MHC) genes dependent. In the present study, we further used DA and DA.1U rats to investigate the role of MHC genes in formalin-induced pain model by behavioral, electrophysiological and immunohistochemical methods. Behavioral results showed biphasic nociceptive behaviors increased significantly following the intraplantar injection of formalin in the hindpaw of DA and DA.1U rats. The main nociceptive behaviors were lifting and licking, especially in DA rats (P<0.001 and P<0.01). The composite pain scores (CPS) in DA rats were significantly higher than those in DA.1U rats in both phases of the formalin test (P<0.01). Electrophysiological results also showed the biphasic increase in discharge rates of C and A? fibers of L5 dorsal root in the two strains, and the net change of the discharge rate of DA rats was significantly higher than that of DA.1U rats (P<0.05). The mechanical thresholds decreased after formalin injection in both strains (P<0.01), and the net change in the mechanical threshold in DA was greater than that in DA.1U rats (P<0.05). The expression of RT1-B, representation of MHC class II molecule, in laminae I-II of L4/5 spinal cord in DA rats was significantly higher than that in DA.1U rats in the respective experimental group (P<0.05). These results suggested that both DA and DA.1U rats exhibited nociceptive responses in formalin-induced pain model and DA rats were more sensitive to noxious chemical stimulus than DA.1U rats, indicating that MHC genes might contribute to the difference in pain sensitivity. PMID:25861730

  5. Motion ReparametrizationMotion Reparametrization Fernando Wagner da SilvaFernando Wagner da Silva

    E-print Network

    Motion ReparametrizationMotion Reparametrization Fernando Wagner da SilvaFernando Wagner da Silva of reparametrization function (g'(t)) ­ more suitable for time-dependent applications. #12;Discrete Reparametrization

  6. Tese Doutoramento Cotutela Internacional U.Minho: Cincias da Comunicao, Teoria da Cultura

    E-print Network

    Boyer, Edmond

    ! ! Tese Doutoramento Cotutela Internacional U.Minho: Ciências da Comunicação, Teoria da Cultura U.ParisDescartes: Sociologia 22 de junho de 2013, Paris Maria da Luz CORREIA Intermitências na cultura visual contemporânea: o-00932174,version1-16Jan2014 #12;7 resumo intermitências na cultura visual contemporânea: o postal ilustrado

  7. Influência da metodologia de avaliação da camada semi-redutora em radiologia diagnóstica

    Microsoft Academic Search

    Marco Aurélio de Sousa Lacerda; Teógenes Augusto da Silva; Arno Heeren de Oliveira

    2007-01-01

    OBJETIVO: A análise crítica da metodologia de medida da camada semi-redutora em feixes de raios X teve como base o regulamento técnico para proteção radiológica e controle de qualidade em radiodiagnóstico médico e odontológico. MATERIAIS E MÉTODOS: Na medida da camada semi-redutora, a técnica radiográ- fica, o arranjo experimental, os meios espalhadores, a instrumentação, o tamanho de campo de radiação

  8. UMA A NÁLISE DA HISTÓRIA DA E LETRICIDADE PRESENTE E M L IVROS DIDÁTICOS: O C ASO DE BENJAMIN FRANKLIN

    Microsoft Academic Search

    Cibelle Celestino Silva; São Carlos SP

    Este trabalho analisa como a história da eletricidade é apresenta- da em livros didáticos e paradidáticos voltados para os Ensinos Fundamental e Médio. Em particular, analisamos como as contri- buições de Benjamin Franklin são abordadas do ponto de vista da qualidade das informações históricas e das idéias sobre a nature- za da ciência induzidas por estas narrativas. A História da

  9. Ministrio da Educao Secretaria de Educao Superior

    E-print Network

    Maier, Rudolf Richard

    Comunitários: Prof. Eduardo Raupp de Vargas Decano de Administração: Prof. Pedro Murrieta Santos Neto Decana de: Hélio Marcos Neiva ­ Diretor de Planejamento Jorge Rodrigues Lima ­ Coordenador de Planejamento e ­ Administradora Thaís Caroline da Silva Dias ­ Estagiária Técnica Responsáveis pelos Demonstrativos da Programação

  10. O ESPAÇO DA UVA TRANSFORMADO EM AGRONEGÓCIO

    Microsoft Academic Search

    Mariza Cezira Campagner; Gervasio Castro de Rezende

    2008-01-01

    O presente artigo tem por objetivo apresentar algumas das redefinições do trabalho agrícola resultantes do processo de reestruturação do espaço da uva transformado em agronegócio, no qual se tem expandido o agronegócio de frutas tropicais. A metodologia está organizada em torno de atualização da pesquisa bibliográfica e as temáticas de interesse; realização de trabalhos na área de estudo. Conclui que

  11. MINISTRIO DA EDUCAO CONSELHO NACIONAL DE EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    todas as crianças na faixa etária que se propõem a atender; II ­ realizar atendimento educacional magistério e dos funcionários da unidade educacional; VI ­ garantir o direito à formação profissional ­ apresente os fins e objetivos da unidade educacional; III ­ explicite uma concepção de criança, de

  12. MINISTRIO DA EDUCAO UNIVERSIDADE FEDERAL DO PARAN

    E-print Network

    Paraná, Universidade Federal do

    Programa de Pós-graduaçáo em Direito da Faculdade de Direito da Universidade Federal do Paraná, no uso de-graduaçáoem Direito, resolve: Art. 1.O - Tornar pública as referências bibliográficas para a prova de disciplinas acordo com a edição). BOBBIO, Norberto.Teoria Geral do Direito. São Paulo: Martins Fontes, 2007. DAHL

  13. MINISTRIO DA EDUCAO UNIVERSIDADE FEDERAL DO PARAN

    E-print Network

    Paraná, Universidade Federal do

    DIREITO REGIMENTO SETORIAL Aprovado pela Resolução nº 181/85, do Conselho de Administração, em 23 Jurídicas da Universidade Federal do Paraná compreende a Faculdade de Direito, fundada na cidade de Curitiba São finalidades da Faculdade de Direito: I - ministrar o ensino do Direito, proporcionando a formação

  14. Origin of the DA and non-DA white dwarf stars

    NASA Technical Reports Server (NTRS)

    Shipman, Harry L.

    1989-01-01

    Various proposals for the bifurcation of the white dwarf cooling sequence are reviewed. 'Primordial' theories, in which the basic bifurcation of the white dwarf sequence is rooted in events predating the white dwarf stage of stellar evolution, are discussed, along with the competing 'mixing' theories in which processes occurring during the white dwarf stage are responsible for the existence of DA or non-DA stars. A new proposal is suggested, representing a two-channel scenario. In the DA channel, some process reduces the hydrogen layer mass to the value of less than 10 to the -7th. The non-DA channel is similar to that in the primordial scenario. These considerations suggest that some mechanism operates in both channels to reduce the thickness of the outermost layer of the white dwarf. It is also noted that accretion from the interstellar medium has little to do with whether a particular white dwarf becomes a DA or a non-DA star.

  15. Ministrio da Educao UNIVERSIDADE FEDERAL DO PARAN

    E-print Network

    Paraná, Universidade Federal do

    ) Regime de Trabalho: 20 (vinte) horas semanais Requisitos: Graduação em Pedagogia ou Licenciatura ou Graduação em Pedagogia ou Licenciatura com Mestrado em Educação, obtidas na forma da lei. Tipos de Provas

  16. Testemunhos literários da (e contra) a barbárie no Brasil

    Microsoft Academic Search

    Valmir de Souza

    A literatura tem servido tanto para testemunhar o que aconteceu na história quanto para construir outras visões e possibilidades históricas. Pretende-se abordar nesse trabalho obras literárias que tratam da questão da exclusão política de grupos ou indivíduos contestadores da ordem. Essas obras servem de testemunho da violência na história política do Brasil, mas também se inserem em tradições literárias e

  17. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    Primaz Naiara da Costa Setembro SetembroPedagogia/ Pesquisa e Prática Pedagógica IV Isabela Mascarenhas Licenciatura em Pedagogia Professora Geysa Spitz A. de Abreu UDESC Sonia M. Jordão de Castro Fabio Ilmar da Lopes Denise Lopes da Conceição e Paula Zinate Mendonça da Silva Março Maio Pedagogia Educação Infantil

  18. A Influência da Escola e da Mídia na Obtenção dos Conhecimentos Astronômicos

    Microsoft Academic Search

    W. S. da Cunha; M. R. Voelzke; L. H. Amaral

    2006-01-01

    O universo em que vivemos possui segredos jamais imaginados pelo homem, fruto da pequena proporção que ocupamos diante de um cosmos infinito. A astronomia funciona como um instrumento que sacia a sede humana em desvendar esses segredos, estudando as galáxias, quasares, pulsares além da existência de todos os elementos que preenchem o espaço cósmico, o vácuo, não mais vazio como

  19. FRAGMENTOS DO PENSAMENTO DIALÉTICO NA HISTÓRIA DA CONSTRUÇÃO DAS CIÊNCIAS DA NATUREZA

    Microsoft Academic Search

    Antônio Fernandes; Nascimento Júnior

    Resumo: Este trabalho tem por objetivo identificar uma possível inclinação das ciências naturais em direção ao materialismo dialético. Para tanto, procura-se apresentar a história da dialética a partir da discussão racionalismo\\/empirismo moderno e seus desdobramentos até as tendências dialéticos contem- porâneas. Os autores discutidos são Kant, Hegel, Marx, Engels, Lenin, Horkheimer, Marcuse, Habermas, Bachelard e suas escolas epistemológicas, completadas por

  20. Avaliação clínica e polissonográfica do aparelho BRD no tratamento da Síndrome da Apneia Obstrutiva do Sono

    Microsoft Academic Search

    Cibele Dal-Fabbro; Cauby Maia Chaves Junior; Lia Rita Azeredo Bittencourt; Sergio Tufik

    2010-01-01

    Objetivos: este trabalho de pesquisa teve o intuito de realizar uma avaliação clínica e polisso- nográfica do efeito de um aparelho intraoral (AIO) para tratamento da Síndrome da Apneia Obstrutiva do Sono (SAOS), desenvolvido e testado por duas universidades federais brasilei- ras. Métodos: a amostra constou de 50 pacientes (idades entre 18 e 65 anos, sendo 33 homens e 17

  1. ACORDO DE FUNCIONARIZACIN DO PERSOAL LABORAL DE ADMINISTRACIN E SERVIZOS DA UNIVERSIDADE DA CORUA

    E-print Network

    Fraguela, Basilio B.

    CORUÑA O proceso de funcionarización do persoal laboral de administración e servizos da Universidade da administrativos e de servizos. Esta opción estatutaria facilita ademáis a xestión de todo o persoal de, réxime de obrigas e dereitos así como os procesos de carreira e promoción profesional. Para o estudio e

  2. Estudo da Freqüência da Emissão de Vórtices em uma Harpa Eólica

    Microsoft Academic Search

    Lucas Emanuel Soeira; Edson Del Rio Vieira

    2004-01-01

    Quando um escoamento contorna um corpo não aerodinâmico, sob determinadas circunstâncias, ocorre o fenômeno de emissão de vórtices. A freqüência de emissão dos turbilhões depende da geometria do corpo, do ângulo de incidência, das propriedades do meio fluido e da velocidade do escoamento. Freqüentemente, o desprendimento cíclico dos vórtices provocam forças de excitação fazendo o corpo vibrar. Esse fenômeno pode

  3. EDITAL n 007/2013 PPGD RESULTADO DA PRIMEIRA ETAPA DA SELEO DOUTORADO 2013

    E-print Network

    Paraná, Universidade Federal do

    PROGRAMA DE PÓS-GRADUAÇÃO EM DIREITO da Faculdade de Direito do Setor de Ciências Jurídicas da Universidade no Doutorado 2013. NOME DISCIPLINA ORIENTADOR MÉDIA FINAL RESULTADO 01 Alexandre Ricardo Pesserl Direito Talamini 3,71 REPROVADO 03 Andreia Izamara Kerber Filosofia do Direito José Antonio Gediel 7,91 APROVADO E

  4. EDITAL n 007/2013 PPGD RESULTADO DA SEGUNDA ETAPA DA SELEO DOUTORADO 2013

    E-print Network

    Paraná, Universidade Federal do

    PROGRAMA DE PÓS-GRADUAÇÃO EM DIREITO da Faculdade de Direito do Setor de Ciências Jurídicas da Universidade Kerber Filosofia do Direito José Antonio Gediel DESFAVORÁVEL 02 Bruno Augusto Vigo Milanez D. Processual Filosofia do Direito Cesar Serbena FAVORÁVEL 06 Emerson Luis Dal Pozzo Direito Empresarial Marcia Carla

  5. Estimação da Atitude de Satélites Artificiais com o Método da Máxima Verossemelhança

    Microsoft Academic Search

    Maria Cecília Zanardi; Valcir Orlando

    2005-01-01

    A determinação da atitude de satélites artificiais consiste e m estimar a orientação espacial do veículo espacial em relação a um sistema de referência (em geral o sistema equatorial da Terra), a partir de dados fornecidos por sensores de atitude a bordo do satélite. Para descrever a atitude do satélites são utilizados os quatérnions e as matrizes de rotação que

  6. PROGRAMA DE MELHORIA DA QUALIDADE E DO AUMENTO DA QUANTIDADE DA ÁGUA DE MANANCIAIS, ATRAVÉS DE INCENTIVOS FINANCEIROS AOS PRODUTORES RURAIS (PROGRAMA DO PRODUTOR DE ÁGUA ANA)

    Microsoft Academic Search

    Henrique M. Leite Chaves; Antônio Félix Domingues; Íris Roitman

    Resumo - Apesar de programas de conservação do solo e da água terem sido implantados no Pais nos últimos 20 anos, os quais aportaram benefícios indiretos para os recursos hídricos, o enfoque dominante era a redução da erosão dentro da propriedade. Entretanto, com a ameaça de crise de abastecimento de água, e com a escassez e a poluição de vários

  7. Aplicação da microcirurgia no serviço de cirurgia plástica da universidade federal da bahia: análise dos resultados e complicações

    Microsoft Academic Search

    Marcelo Sacramento Cunha; Rogério dos Santos Ramos; André Leal Gonçalves Torres; Deise de Azevedo Monteiro e Souza; Ivan Marcelo Gonçalves Agra; José Neiva Eulálio

    2005-01-01

    RESUMO: Objetivo: O estudo pretende relatar a experiência inicial de um serviço de cirurgia plástica ao implantar um grupo de microcirurgia, analisando as complicações e resultados da casuística. Método: No período de fevereiro de 2003 a junho de 2004, foram realizados 20 procedimentos de microcirurgia reconstrutiva variando em reconstruções de cabeça e pescoço, mama e membros inferi ores. As complicações

  8. XXIV Congresso Brasileiro de Biblioteconomia, Documentao e Cincia da Informao

    E-print Network

    Paraná, Universidade Federal do

    e conhecimentos sobre a flexibilização curricular sob a nova visão da pedagogia social e o perfil de progressivas criando escolas inclusivas de qualidade e plantado na pedagogia a questão da inclusão, seja pelas

  9. Ministrio da Educao Universidade Federal do Paran

    E-print Network

    Paraná, Universidade Federal do

    Extensão AVALIAÇÃO PERIODONTAL DE DEPENDENTES QUÍMICOS Coordenador(a) Maria Ângela Naval Machado Unidade de discussão em grupo de temas de saúde bucal -Confecção e apresentação de palestras sobre doença periodontal. -Diagnóstico da doença periodontal (exame clínico periodontal e anotação dos dados coletados em ficha própria

  10. MINISTRIO DA EDUCAO UNIVERSIDADE FEDERAL DO PARAN

    E-print Network

    Paraná, Universidade Federal do

    COMPRAS, CONTRATOS E PATRIMÔNIO PREGÃO ELETRÔNICO Nº 142/2013 =SRP VALIDADE 13/01/14 a 12/01/15 AQUISIÇÃO COMPRAS, CONTRATOS E PATRIMÔNIO 2 Balança Analítica - Capacidade de pesagem até 210 GRS, sens . 0,0001g. ambiente até 100ºC; Resolução: Incrementos de 1ºC; Estabilidade da Temperatura: ± 1ºC; Controle de

  11. MINISTRIO DA EDUCAO UNIVERSIDADE FEDERAL DO PARAN

    E-print Network

    Paraná, Universidade Federal do

    SERVIÇOS GERAIS CENTRAL DE COMPRAS, CONTRATOS E PATRIMÔNIO Rua XV de Novembro, 1299 ­ Centro ­ CEP 80060 ambientes abertos ou fechados, conforme necessidade da UFPR. Equipamento necessário: · 4 moving head 575 ADMINISTRAÇÃO DIVISÃO DE SERVIÇOS GERAIS CENTRAL DE COMPRAS, CONTRATOS E PATRIMÔNIO Rua XV de Novembro, 1299

  12. MINISTRIO DA EDUCAO UNIVERSIDADE FEDERAL DO PARAN

    E-print Network

    Paraná, Universidade Federal do

    COMPRAS, CONTRATOS E PATRIMÔNIO PREGÃO ELETRÔNICO Nº 21/2014 =SRP VALIDADE 25/06/14 a 24 PRÓ-REITORIA DE ADMINISTRAÇÃO DSG/CENTRAL DE COMPRAS, CONTRATOS E PATRIMÔNIO proporcionar maior: ± 2,5ºC. Temperatura mínima de 15ºC acima da temperatura ambiente. Sensor de temperatura tipo J

  13. Estudo da Influncia de Seqncias Polipeptdicas e

    E-print Network

    Neshich, Goran

    (Creighton, 1993). Pontes de hidrogênio entre resíduos linearmente próximos estabilizam estas conformações da formação de pontes de hidrogênio entre o átomo de hidrogênio ligado ao átomo de nitrogênio tendo em vista que todos os resíduos participam das pontes de hidrogênio (com exceção dos resíduos das

  14. The PAN-DA data acquisition system

    SciTech Connect

    Petravick, D.; Berg, D.; Berman, E.; Bernett, M.; Constanta-Fanourakis, P.; Dorries, T.; Haire, M.; Kaczar, K; MacKinnon, B.; Moore, C.; Nicinski, T.; Oleynik, G.; Pordes, R.; Sergey, G.; Votava, M.; White, V.

    1989-05-01

    The Online and Data Acquisition software groups at Fermi National Accelerator Laboratory have extended the VAXONLINE data acquisition package to include a VME based data path. The resulting environment, PAN-DA, provides a high throughput for logging, filtering, formatting and selecting events. 10 refs., 1 fig.

  15. Ministrio da Educao Universidade Federal do Paran

    E-print Network

    Paraná, Universidade Federal do

    Ministério da Educação Universidade Federal do Paraná Pró-Reitoria de Extensão e Cultura Anexo I. Rosato Unidade de origem (Depto/Setor) MAE/PROEC Área temática do Programa/ Projeto Cultura. Carga etnologia indígena. - Área de Cultura Popular: O bolsista irá desenvolver atividades com o acervo de Cultura

  16. Common colds on Tristan da Cunha

    PubMed Central

    Shibli, M.; Gooch, S.; Lewis, H. E.; Tyrrell, D. A. J.

    1971-01-01

    Eight epidemics of respiratory disease have been observed among islanders of Tristan da Cunha. They seem to be initiated by the arrival of ships and transmission seemed to occur as a result of close human contact but could not always be traced. Islanders suffered from less colds than those in less isolated communities. PMID:5282927

  17. MINISTRIO DA EDUCAO UNIVERSIDADE FEDERAL DO PARAN

    E-print Network

    Paraná, Universidade Federal do

    -graduação em Direito Praça Santos Andrade, 50 ­ 3º Andar Tel.:(41)3310-2685 e 3310-2739 www.direito.ufpr.br/ppgd Portaria n.º 0029/2012-PPGD O Coordenador do Programa de Pós-Graduação em Direito da Faculdade de Direito Direito, História do Direito, Sociologia do Direito, Teoria do Estado, Teoria Geral do Direito ­ Prof. Dr

  18. [An overestimated technician - Leonardo da Vinci].

    PubMed

    Szabadvary, F

    The reasons are discussed why Leonardo da Vinci is being overestimated as engineer and inventor, although the majority of his drawings concerning engineering are not beyond the level of contemporary engineering knowledge and he never attempted to carry out those which would have been novel in fact. PMID:11625571

  19. O IMPACTO DA ARMAZENAGEM DA SOJA NA PROPRIEDADE RURAL SOBRE OS PREÇOS DE MERCADO DA COMMODITY E NA AMPLIAÇÃO DA CAPACIDADE DE ARMAZENAMENTO

    Microsoft Academic Search

    Lenio Tramontina; Edson Talamini; Gabriel Murad Velloso Ferreira

    2008-01-01

    O presente trabalho consiste em um estudo realizado com objetivo principal de avaliar o impacto do aumento na capacidade de armazenagem de soja na propriedade rural, sobre o nível de preços da commodity e deste sobre a viabilidade de novos incrementos na capacidade de armazenagem. Para o seu desenvolvimento aplicou-se um estudo exploratório, baseado no levantamento e análise de dados

  20. Reunio da PROPG/UFSC com os Coordenadores de PPGs

    E-print Network

    Floeter, Sergio Ricardo

    . Bolsas e Distribuição de bolsas Emergenciais 6. Bolsas PIAPE/Coréia/ Leiden (Holanda) 7. Plataforma da República da Coréia Inscrição: até 14/03/2014 #12;7. Plataforma Sucupira/CAPES · Lançamento da Plataforma no dia 27/03/2014 · Curso de Treinamento na CAPES · Cursos de Treinamento na UFSC #12;8. Tutorial

  1. A ROBÓTICA PEDAGÓGICAO COTEXTO DA EDUCAÇÃO IFATIL: AUXILADO O ALFABETISMO

    Microsoft Academic Search

    Akynara Aglaé; R. S. da Silva; Graças P. Coelho; Renata Pitta Barros; Luiz Marcos; G. Gonçalves

    A presente pesquisa expõe um pouco do percurso histórico da robótica aplicada à educação, seu aparecimento, características e benefícios para a aprendizagem, buscando respaldo no Projeto de Inclusão Digital com Robôs, desenvolvido pelo Departamento de Engenharia de Computação e Automação da Universidade Federal do Rio Grande do Norte, para descrever uma das propostas de aplicação da robótica pedagógica no âmbito

  2. Ministrio da Educao -MEC Universidade Federal do Paran UFPR

    E-print Network

    Paraná, Universidade Federal do

    Atendimento Educacional Especializado na Perspectiva da Educação Inclusiva 1 EDITAL195/2014 CIPEAD/PROGRAD/UFPR Resultado da seleção de alunos CURSO DE APERFEI�OAMENTO EM ATENDIMENTO EDUCACIONAL ESPECIALIZADO NA EDUCACIONAL ESPECIALIZADO NA PERSPECTIVA DA EDUCA��O INCLUSIVA. Para os polos de Araucária, Pinhais e

  3. O PAPEL da FAPERGS no FOMENTO O PAPEL da FAPERGS no FOMENTO PESQUISA no BRASILPESQUISA no BRASIL

    E-print Network

    Barbosa, Marcia C. B.

    O PAPEL da FAPERGS no FOMENTO àO PAPEL da FAPERGS no FOMENTO à PESQUISA no BRASILPESQUISA no BRASILPrograma Estímulo à Interação EmpresarialInteração Empresarial A FAPERGS foi pioneira no Brasil na criação do

  4. Spécificité 52 kDa et 60 kDa des anti-Ro(SSA) dans les connectivites inclassables

    Microsoft Academic Search

    Norma Belfiore; Silvia Rossi; Francesca Bobbio-Pallavicini; Oscar Epis; Roberto Caporali; Carlomaurizio Montecucco

    2000-01-01

    Anti-Ro(SS-A) 52 kDa and 60 kDa specificities in undifferentiated connective tissue disease. — Objective. Autoantibodies to Ro(SS-A) may recognize two different polypeptides, of 52 kDa and 60 kDa, respectively. Methods. We used an ELISA with purified human recombinant antigens to conduct a detailed analysis of the specificities of anti-Ro(SS-A) antibodies from 170 patients with definite diagnoses (systemic lupus erythematosus [SLE],

  5. UNIVERSIDADE DA CORUA CONVOCATORIA DE ADMISiN E MATRfCULA NOS ESTUDOS DE DOUTORAMENTO DA

    E-print Network

    Fraguela, Basilio B.

    Estatutos da Universidade da Coruña, aprobados polo Decreto da Xunta de Galicia 101/2004, do 13 de maio, modificado polo Decreto 194/2007, do 11 de outubro; no Real Decreto 99/2011, de 28 de xaneiro, polo que se aprobado polo Consello de Goberno do 17/07/2012 e as modificacións introducidas polo Consello de Goberno do

  6. Qual o Papel da Escola e da Mídia na Obtenção dos Conhecimentos Astronômicos?

    NASA Astrophysics Data System (ADS)

    da Cunha, W. S.; Voelzke, M. R.; Amaral, L. H.

    2007-08-01

    É amplamente reconhecido que as pessoas em geral têm grande fascínio e interesse pela Astronomia. Por outro lado, o conteúdo dessa área incluído no ensino formal está longe de ser abrangente e suficiente para suprir a demanda. Esse interesse permite aperfeiçoar a divulgação e o ensino não formal de Astronomia através da mídia aliando a adequação do conteúdo à expectativa das pessoas. A reforma do Currículo Básico da Escola Pública da maioria dos Estados brasileiros tem introduzido Astronomia desde a pré-escola até o Ensino Médio. Num estudo realizado com 1180 alunos do Ensino Médio de seis escolas estaduais, revelou-se através da aplicação de um formulário contendo questões que abordavam conhecimentos básicos em Astronomia, como foram adquiridos tais conhecimentos e à infra-estrutura da escola. Para 66,1% dos entrevistados o professor já fez alguma apresentação a respeito de Astronomia. O presente estudo revelou também que 54,4% dos alunos entrevistados adquiriram seus conhecimentos astronômicos na escola, 18,4% através da televisão e 27,1% afirmaram que seus conhecimentos foram obtidos através de outros tipos de mídia (internet, livros didáticos, filmes e revistas). Embora o estudo revele claramente que há certo equilíbrio no meio em que os alunos obtiveram seus conhecimentos astronômicos, a mídia busca não somente sua difusão, mas a disponibilização desse conhecimento de maneira correta, que às vezes, não é atingido, apresentando conceitos sem fundamentação e incorretos. Por outro lado, no dia-a-dia escolar, é comum encontrar professores que vêm para as aulas com concepções prévias, que podem diferir substancialmente das idéias a serem ensinadas, dificultando o aprendizado de futuros conceitos científicos. Uma avaliação criteriosa, avaliando as dificuldades dos professores em determinar o sentido correto dos conceitos e observando a metodologia que utilizam no ensino, poderá proporcionar uma melhor compreensão sobre as concepções alternativas, presentes no ensino de Astronomia.

  7. A contribuição dos educadores ambientais do Projeto Baleia Franca na manutenção da biodiversidade da APA da Baleia Franca, Santa Catarina, Brasil

    Microsoft Academic Search

    Giselle Paes Horacio; Nínive da Costa Acosta; Karina Rejane Groch

    RESUMO As atividades de educação ambiental realizadas pelo Projeto Baleia Franca na Área de Proteção Ambiental (APA) da Baleia Franca, no período de outubro de 2005 a outubro de 2006, tiveram a baleia franca austral (Eubalaena australis), espécie ameaçada de extinção, como âncora principal. Foram abordados temas como biodiversidade, preservação da natureza, manejo e outras problemáticas ligadas à área protegida

  8. DIAGNÓSTICO DA AMBIÊNCIA ORGANIZACIONAL DA COMUNIDADE DE PRODUTORES DE PIMENTA LONGA (PIPER HISPIDINERVUM) UNIÃO DA LINHA SEIS DO PROJETO DE COLONIZAÇÃO HUMAITÁ EM PORTO ACRE – AC

    Microsoft Academic Search

    Solange Maria Chalub Bandeira Teixeira; Lucas Araujo Carvalho

    2008-01-01

    Este trabalho apresenta o resultado parcial de uma pesquisa maior sobre a avaliação ambiental e sócio-econômica da produção de pimenta longa (Piper hispidinervum) de uma comunidade de produtores de um projeto de colonização do INCRA. Trata-se da sistematização do que foi levantado em campo, através de pesquisa realizada com 10 (dez) produtores rurais, pertencentes a uma associação de produtores do

  9. Leonardo Da Vinci's right-to-left "mirrored" writing revisited.

    PubMed

    Reinke, K R

    1993-01-01

    Leonardo Da Vinci's anatomical drawings continue to attract the attention of the medical community. One of the intriguing aspects of these drawings is Da Vinci's use of right-to-left mirrored writing. Many hypotheses have been proposed to explain his mirrored writing. This article presents a new explanation that takes into consideration the drawing material used and Da Vinci's known innovative ability. A collection of his anatomical drawings is currently on display in Boston at the Museum of Fine Arts. PMID:8333692

  10. DA495 - an aging pulsar wind nebula

    Microsoft Academic Search

    R. Kothes; T. L. Landecker; W. Reich; S. Safi-Harb; Z. Arzoumanian

    2008-01-01

    We present a radio continuum study of the pulsar wind nebula (PWN) DA 495\\u000a(G65.7+1.2), including images of total intensity and linear polarization from\\u000a408 to 10550 MHz based on the Canadian Galactic Plane Survey and observations\\u000awith the Effelsberg 100-m Radio Telescope. Removal of flux density\\u000acontributions from a superimposed \\\\ion{H}{2} region and from compact\\u000aextragalactic sources reveals a

  11. COMISSO CPA ATA DA REUNIO DE 14.09.07

    E-print Network

    Paraná, Universidade Federal do

    . Estiveram presentes os membros do comitê da CPA: Anna Jungbluth (PROGRAD), Professor Robson Tadeu Bolzon-Avaliação. Paulo Tetuo Yamamoto: __________________________________________________ Robson Tadeu Bolzon

  12. Pedagogia ambiental e pedagodia da complexidade: da tríade à Educação Humanista

    Microsoft Academic Search

    Eduardo Marandola Jr; Marcos Takeda

    2007-01-01

    Há um consenso entre aqueles que se dedicam a pensar a Educação: o Ensino Tradicional não é adequado à nossa sociedade contemporânea. Porém, a sua inadequabilidade não significa, necessariamente, que dele nada se aproveite. A tentativa de superação do tradicional foi empreendida por mais de uma forma de pensamento, que buscaram, através da negação do anterior, legitimar-se. Contudo, estas tentativas

  13. UNIVERSIDADE FEDERAL DO PARAN -SETOR DE CINCIAS DA SADE SIBI -BIBLIOTECA DE CINCIAS DA SADE -SD

    E-print Network

    Paraná, Universidade Federal do

    de livros e livros. Antonio Carlos Ligocki Campos et al. Influence of bariatric surgery on circadian-280, 2008. 2008 Medline Artigo #12;Antonio Carlos Ligocki Campos et al The impact of bariatric surgery Plastic Surgery, v.33, p.84-89, 2009. 2009 Medline Artigo Antonio Carlos Ligocki Campos et al Efeito da

  14. Diretrizes curriculares da pedagogia: imprecisões teóricas e concepção estreita da formação profissional de educadores

    Microsoft Academic Search

    José Carlos Libâneo

    2006-01-01

    RESUMO: A Resolução do CNE que institui as Diretrizes Curriculares Nacionais para os cursos de graduação em pedagogia reacende o deba- te em torno da natureza do conhecimento pedagógico, do curso de pe- dagogia, dos cursos de licenciatura para a formação de professores e do exercício profissional de professores e especialistas em educação. Este artigo traz uma exposição crítica ao

  15. A NATUREZA DA CIÊNCIA E A INSTRUMENTAÇÃO PARA O ENSINO DA FÍSICA

    Microsoft Academic Search

    Alexandre Medeiros; Severino Bezerra Filho

    2000-01-01

    Resumo: O propósito deste artigo é o de examinar as convicções filosóficas que dão suporte aos compor- tamentos de alguns professores de física ao lidarem com o ensino da Física no contexto de um laborató- rio. Entrevistas foram feitas com professores de \\

  16. Influência da utilização da órtese de tornozelo durante atividades do voleibol: avaliação eletromiográfica

    Microsoft Academic Search

    Jefferson Rosa Cardoso; Christiane de Souza Macedo Guerino; Marcelo Bannwart Santos; Thiago André Del Arco Mustafá; Anália Rosário Lopes; Marcelo Costa de Paula

    2005-01-01

    RESUMO Entorse de tornozelo é a lesão aguda mais freqüentemente en- contrada no voleibol. Com o intuito de prevenir a ocorrência de lesões de tornozelos, foram desenvolvidos equipamentos profilá- ticos, como as órteses. O objetivo deste estudo foi avaliar o de- sempenho dos músculos do tornozelo (tibial anterior, fibular longo e gastrocnêmio - porção medial e lateral) por meio da

  17. Depth asymmetry in da Vinci stereopsis.

    PubMed

    Häkkinen, J; Nyman, G

    1996-12-01

    We investigated processes that determine the depth localization of monocular points which have no unambiguous depth. It is known that horizontally adjacent binocular objects are used in depth localization and for a distance of 25-40 min arc monocular points localize to the leading edge of a depth constraint zone, which is an area defined by the visibility lines between which the points in the real world must be. We demonstrate that this rule is not valid in complex depth scenes. Adding other disparate objects to the scene changes the localization of the monocular point in a way that cannot be explained by the da Vinci explanation of monocular-binocular integration. The effect of additional disparate objects is asymmetric in depth: a crossed object does not affect the da Vinci effect but an uncrossed object biases the depth localization of monocular objects to uncrossed direction. We conclude that a horizontally adjacent binocular plane does not completely determine the depth localization of a monocular point and that depth spreading from other binocular elements biases the localization process. PMID:8994582

  18. Modellistica idrometeorologica dei deflussi da scioglimento nivale Paola Allamano

    E-print Network

    Poggi, Davide

    Modellistica idrometeorologica dei deflussi da scioglimento nivale Paola Allamano Politecnico di Torino, 19 Maggio 2004 Nell'ambito della tesi di laurea "Modellistica idrometeorologica dei deflussi da'indagine dei meccanismi che intervengono nel processo di scioglimento della copertura nevosa ed alle modalità

  19. SIMONE DINIZ JUNQUEIRA BARBOSA MODELAGEM E ESPECIFICAO DA NAVEGAO

    E-print Network

    Barbosa, Simone Diniz Junqueira

    SIMONE DINIZ JUNQUEIRA BARBOSA MODELAGEM E ESPECIFICAÇÃO DA NAVEGAÇÃO EM APLICAÇÕES HIPERMÍDIA DISSERTAÇÃO DE MESTRADO Departamento de Informática Rio de Janeiro, 22 de Fevereiro de 1995 #12;SIMONE DINIZ Informática: Ciência da Computação. Orientador: Prof. Daniel Schwabe. Departamento de Informática Pontifícia

  20. Fundao Universidade de Braslia 8 RELATRIO DE ATIVIDADES DA COMISSO

    E-print Network

    Maier, Rudolf Richard

    Executiva do Projeto de Expansão da UnB (a partir de novembro de 2012). Simone Perecmanis, Representante, Representante Discente do CEPE Daniel Dantas Prazeres, Representante Discente do CEPE Antônio César P. Brasil Executiva do Projeto de Expansão da UNB 03/03. Simone Perecmanis Representante Docente do CEPE 02

  1. Research on Wireless OPC DA Server for Modbus

    Microsoft Academic Search

    Xiaoping Zhou; Xiaoxuan Ma; Hantao Zhang

    2011-01-01

    Based on the study of the drawback of traditional wired automatic control system and current wireless remote monitoring system for Modbus, and the utilization of a Uniform Wireless OPC DA Server, a new solution to construct a wireless OPC DA server for Modbus was given out. It used mobile communication networks and OPC technology. Also, Modbus request command strategy was

  2. Efeitos hemostático e estrutural da esponja de celulose liofilizada

    Microsoft Academic Search

    LUÍS RENATO MELLO; FLAVIA C. NUNES MACHADO; LEANDRO J. HAAS; VANESSA ZACCHI; RICHARD LUZZI; JAMES ZOSCHKE; RODRIGO S. RAMOS

    1998-01-01

    RESUMO - Os efeitos hemostáticos da celulose oxidada (Surgicel) são bem conhecidos. Baseados na similaridade estrutural e em um possível efeito hemostático, estudamos a esponja de celulose liofilizada utilizando dois modelos experimentais. Fase I - Realizada em 12 cães, consistiu na provocação de lesão cortical com sangramento, introdução de fragmento de esponja de celulose liofilizada no interior da lesão e

  3. SEMINRIO INTERNACIONAL: HISTRIA SOCIAL DA CULTURA MESTRADO 25 ANOS

    E-print Network

    SEMINÁRIO INTERNACIONAL: HISTÓRIA SOCIAL DA CULTURA ­ MESTRADO 25 ANOS Data: 8, 9 e 10 de outubro (UNIVERSO) 16:30h às 18:30h ­ Mesa 2: História e Cultura na contemporaneidade / O conceito de cultura hoje. Bernardo Medeiros Ferreira da Silva (UERJ) 16:30h às 18:30h - Mesa 4: História e Cultura na

  4. Desdobramentos de Curto e Médio Prazo da Crise Atual

    Microsoft Academic Search

    Luciana Acioly; Milko Matijascic; Emilio Chernavsky; Maria Piñón; Rodrigo Pimental Ferreira Leão

    2009-01-01

    A crise financeira internacional aprofundou-se no último trimestre de 2008. As multinacionais procuram se adaptar, as instituições multilaterais debatem soluções e os governos aumentam sua capacidade de intervenção na economia. O presente texto escreve as origens da crise internacional e discute algumas de suas características,mostrando a evolução recente de alguns indicadores macroeconômicos em países selecionados, e os efeitos da crise

  5. Carlos Affonso de Souza Marco Civil da Internet

    E-print Network

    Floeter, Sergio Ricardo

    Doutor e Mestre em Direito Civil pela Universidade do Estado do Rio de Janeiro (Uerj). Diretor do Faculdade de Direito da Universidade de Yale. Professor Visitante nos cursos de graduaçãoepós relacionadas ao Direito Civil e a à interface entre Direito e Tecnologias da Informação e Comunicação. Membro

  6. NOVAS TECNOLOGIAS DA INFORMAÇÃO E COMUNICAÇÃO APLICADAS NO DESENVOLVIMENTO DO PENSAMENTO CRIATIVO COM O ENFOQUE DA PEDAGOGIA EMPREENDEDORA

    Microsoft Academic Search

    Carlos Ribeiro da Silva; Renê Gomes Pimentel; Faculdade Baiana de Ciências

    Resumo Neste artigo aborda-se o impacto das novas tecnologias da informação e comunicação para proporcionar o potencial criativo dos indivíduos. O texto aborda uma proposta de uma pedagogia empreendedora utilizando-se das novas tecnologias para propiciar uma melhor retenção da inform ação, com as multimídias capazes de combinar diferentes sistemas simbólicos e interativos. Faz uma abordagem do pensamento criativo e como

  7. 75 FR 52292 - Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 40 and DA 40F Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-25

    ...2120-AA64 Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 40...airworthiness directive (AD) for all Diamond Aircraft Industries GmbH Models DA 40...identified in this proposed AD, contact Diamond Aircraft Industries GmbH, N.A....

  8. HeDaM: The Herschel Database in Marseille

    NASA Astrophysics Data System (ADS)

    Roehlly, Y.; Buat, V.; Heinis, S.; Moreau, C.; Gimenez, S.

    2011-07-01

    The Herschel Database in Marseille (HeDaM) is an information system operated by the Laboratoire d'Astrophysique de Marseille (LAM) datacenter — CeSAM. Gathering data from various Herschel Space Observatory surveys, HeDaM serves both as a collaboration tool between scientists and as a way to distribute public data to a wider community. With HeDaM, users have access to the direct download of catalogs and maps, but also to value-adding services such as: multi-? FITS cut-outs, integration with Aladin applet and Topcat, and list-based cone searches.

  9. Universidade de Braslia Faculdade de Cincias da Sade

    E-print Network

    Maier, Rudolf Richard

    Pesquisa em: Farmacologia e Toxicologia ­ 01 (uma) vaga #12;2 2.2.2 Mestrado Acadêmico: 1. Área de: Farmacologia e Toxicologia ­ 01 (uma) vaga 3. DA INSCRIÇÃO AO PROCESSO SELETIVO 3.1 As inscrições para o

  10. PODER JUDICIRIO TRIBUNAL DE JUSTIA DO ESTADO DA BAHIA

    E-print Network

    Maier, Rudolf Richard

    OSÉAS COSTA DE SOUSA; Juíza de Direito MARIANA TEIXEIRA LOPES; e Bacharel ANDRÉ LUIS GUIMARÃES GODINHO, representante da OAB. Dado e passado nesta Cidade do Salvador, aos 22 dias do mês de maio de 2012. DES. MARIO

  11. XXIV Congresso Brasileiro de Biblioteconomia, Documentao e Cincia da Informao

    E-print Network

    Paraná, Universidade Federal do

    Londrina Eliane M. S. Jovanovich emsjovanovich@uel.br Universidade Estadual de Londrina RESUMO Muito se-se verificar o que o Sistema de Bibliotecas da Universidade Estadual de Londrina - SB/UEL está fazendo para

  12. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    (048) 3721-8921 QUESTIONÁRIO EVASÃO DATA: POLO: ESTADO: COORDENADOR ADJUNTO DE POLO: ESTUDANTE: FONE: AVALIAÇÃO DA ESTRUTURA DO POLO: ( ) BOM ( ) REGULAR ( ) RUIM OBS: AVALIAÇÃO DO COORDENADOR DE POLO: ( ) BOM

  13. ISSN 0103-9741 Monografias em Cincia da Computao

    E-print Network

    Endler, Markus

    (cfelicissimo, sardinha, lucena)@inf.puc-rio.br Abstract. Inspired by the Tim Berners-Lee's vision of a Semantic. Inspirado pela visão de Tim Berners-Lee da Web Semântica, este trabalho vi- as apresentar uma aproximação

  14. Variabilidade sazonal dos constituintes da própolis vermelha e bioatividade em Artermia salina

    Microsoft Academic Search

    Lívio César Cunha Nunes; Alexandre Bezerra Galindo; Annalu da Silva Oliveira de Deus; Daniel Arcanjo Rufino; Karina Perrelli Randau; Haroudo Satiro Xavier; Antônia Maria das Graças Lopes Citó; Pedro José Rolim Neto

    2009-01-01

    RESUMO: A própolis é uma substância resinosa coletada pelas abelhas de diversas partes das plantas. Sua composição depende da época, vegetação e local de coleta. Apresenta diversas atividades biológicas como antimicrobiana, antioxidante, antitumoral, dentre outras. Foi realizado estudo da variabilidade sazonal, nos meses de fevereiro, junho e outubro de 2006, dos constituintes voláteis da própolis vermelha de Pernambuco através da

  15. Universidade Federal de Santa Catarina-Campus Joinville Centro de Engenharia da Mobilidade

    E-print Network

    Floeter, Sergio Ricardo

    .petemb.ufsc.br BoletimInformativo Editorial O PET CEM ­ Programa de Educação Tutorial da Engenharia da Mobilidade da engenharia da mobilidade estamos lançando este Boletim Informativo Bimestral, o qual tem o objetivo de.petemb.ufsc.br A parapsicologia como uma ciência Apresentação e texto elaborado pelo Bolsista Daniel Rossi Korol A parapsicologia

  16. MÉTODOS DE REGENERAÇÃO IN VITRO DA MAMONEIRA A PARTIR DE DIFERENTES TIPOS DE EXPLANTES1

    Microsoft Academic Search

    MARIA SOCORRO ROCHA; KÁTIA CRISTINA DE OLIVEIRA; ADRIANE OLIVEIRA CUNHA; JOSÉ WELLINGTON DOS SANTOS

    4 RESUMO: Considerando-se o elevado índice de contaminação de sementes no processo de sua multiplicação e a necessidade da manutenção da qualidade fisiológica da semente de Banco de Germoplasma é que objetivou-se estudar métodos de regeneração da mamoneira a partir de diferentes tipos de explantes e sua contaminação in vitro, através dos seguintes explantes: sementes inteiras, quebradas e sem tegumento

  17. Estado, mercado e sociedade civil: conversações em torno da responsabilidade social

    Microsoft Academic Search

    Vanessa de Souza; Travessa Nestor de Castro; Alexandre Reis; Rua Epaminondas Santos

    2004-01-01

    Resumo: O presente trabalho tem por objetivo analisar o relacionamento do empresariado com os movimentos sociais, ONGs e Estado, partindo de uma revisão da literatura pertinente a este assunto. Bem como, atualizar essa visão a partir da entrevista com uma empresária do setor de marcenaria da cidade de Porto Alegre, e de informações institucionais veiculadas no site oficial da Federação

  18. MICORRIZA ARBUSCULAR EM ESPÉCIES ARBÓREAS NATIVAS DA BACIA DO RIO TIBAGI, PARANÁ

    Microsoft Academic Search

    Waldemar Zangaro; Silvio M. A. Nisizaki; Juliana C. B. Domingos; Emilia M. Nakano

    RESUMO: Relata-se a incidência da colonização de micorriza arbuscular (MA) e a resposta à inocu- lação em 81 espécies arbóreas nativas da bacia do rio Tibagi (PR), em condições de casa de vegetação. Também é relatada a incidência da colonização de MA em 51 espécies arbóreas nativas coletadas em áreas em início de sucessão arbórea e no interior da floresta

  19. Thirty-Five New Pulsating DA White Dwarf Stars

    Microsoft Academic Search

    F. Mullally; R. E. Nather; D. E. Winget; Ted von Hippel; S. J. Kleinman; Atsuko Nitta; Jurek Krzesinski; S. O. Kepler; A. Kanaan; D. Koester; D. J. Sullivan; D. Homeier; S. E. Thompson; D. Reaves; C. Cotter; D. Slaughter; J. Brinkmann

    2004-01-01

    We present 35 new pulsating DA (hydrogen atmosphere) white dwarf stars discovered from the Sloan Digital Sky Survey (SDSS) and the Hamburg Quasar Survey (HQS). We have acquired high-speed time series photometry of preselected DA white dwarfs with a prime focus CCD photometer on the 2.1 m telescope at McDonald Observatory over 15 months. We selected these stars on the

  20. DA VINCI X-PRIZE SPACE PROJECT - MISSION ANALYSIS

    Microsoft Academic Search

    Vladimir Kudriavtsev; Brian Feeney; Max Buneta; James Porcher; Asier Ania; Michael Trauttmansdorff; Ta-Liang Hsu; Marek Krzeminski; Kalman Rooz

    In the present article we review engineering and research efforts conducted by a group of volunteers with the help of advanced engineering commercial software (CFD-ACE+, ANSYS, CFD-FASTRAN, Matlab\\/Simulink, Autodesk Inventor, Maple) in support of the da Vinci Project, the first Canadian competitor in the International X Prize Competition. The da Vinci Project has an objective of launching the first commercial

  1. Estudo da região HII galática NGC 2579

    NASA Astrophysics Data System (ADS)

    Riffel, R.; Copetti, M. V. F.

    2003-08-01

    Desde a descoberta dos gradientes de abundância química em galáxias espirais, as regiões HII galáticas têm sido intensamente estudadas com o objetivo de determinar a forma do gradiente de abundância química na Via-Láctea. Entretanto, a forma do gradiente galático continua controversa e existem muitas regiões HII que continuam inexploradas. A região HII galática NGC 2579 é um objeto que aparece em imagens Ha, como uma pequena mancha brilhante de aproximadamente 2 segundos de arco de diâmetro a 20 segundos de arco ao leste de RCW 20, sendo NGC 2579 muitas vezes confundida com esta última. Apesar de seu alto brilho superficial, NGC 2579 é um objeto pouco estudado provavelmente por problemas de identificação deste objeto. Como parte de um projeto de reavaliação dos gradientes de abundância química das regiões HII na Via-Láctea, estamos realizando um estudo extensivo das propriedades físicas básicas como temperatura eletrônica, densidade eletrônica e composição química da região HII galática NGC 2579. Analisamos dados espectrofotométricos de fenda longa na faixa de 3700Å a 7750Å obtidos com o telescópio de 1.52 m do ESO, Chile, em 2002. Determinamos a temperatura eletrônica usando a razão entre as linhas do [OIII] (l4959+l5007/l4363) e a densidade eletrônica pela razão entre as linhas do [SII] (l6716/l6731). As abundâncias químicas do O, N, Cl, S, Ne e He foram determinadas. Realizamos um estudo de imagens fotométricas nas bandas UBVRI obtidas em 2000 no observatório astronômico San Pedro Mártir, México, para identificar e classificar as estrelas ionizantes de NGC 2579 e determinar a distância deste objeto.

  2. A cosmologia no ensino da geografia

    NASA Astrophysics Data System (ADS)

    Santos, S. C.; Chiaradia, A. P. M.

    2003-08-01

    O principal objetivo deste trabalho é auxiliar o professor de Geografia em sala de aula no ensino de tópicos relacionados com a Cosmologia. A idéia deste trabalho surgiu quando foi constatado que o professor de Geografia tem dificuldades de ensinar este tópico. Esta constatação foi feita por uma das autoras ao lecionar este tópico no ensino fundamental e em discussões com outros professores de Geografia. Da mesma maneira que ocorria desde os tempos mais antigos, os alunos têm muito interesse em conhecer os fenômenos que ocorrem no Cosmo, porém os livros didáticos de Geografia utilizados em sala de aula não são ricos em informações sobre este assunto. Assim, o professor de Geografia tem poucas informações para discutir este assunto em sala de aula e não dá a devida importância para este tópico. Então, foi desenvolvido um material de apoio para professores de Geografia sobre a origem do Universo, sua evolução e seu possível futuro evolutivo segundo as mais recentes teorias, com base em perguntas feitas pelos alunos de ensino fundamental e as informações trazidas nos livros didáticos Não cabe a este material inovar e tão pouco trazer uma metodologia de ensino de Cosmologia. Neste material o professor de Geografia pode encontrará um banco de informações, que constitui no estabelecimento de conceitos, teorias e hipóteses, sobre a Cosmologia, em linguagem simples e de fácil entendimento. Para desenvolvê-lo, foram feitas pesquisas não exaustivas em livros e revistas científicas, compilação e discussão em forma cronológica das teorias aceitas sobre modelos cosmológicos. Portanto, este material será apresentado neste trabalho.

  3. DA1 receptors modulation in rat isolated trachea.

    PubMed

    Cabezas, Gloria A; Velasco, Manuel

    2010-01-01

    We have previously demonstrated that low dose of inhaled dopamine (0.5-2 microg kg(-1) min(-1)) induces broncodilatacion in patients with acute asthma attack, suggesting that this dopamine effect is mediated by dopaminergic rather than by adrenergic receptors. To understand better these dopamine effect, rat tracheal smooth muscle was used as a model to evaluate the responses of beta2-, alpha1-, alpha2-adrenergic and DA1 and DA2 dopaminergic antagonists. Tracheal rings from male Sprague-Dawley rats (n = 90) were excised and placed in an organ bath containing modified Krebs-Ringer bicarbonate buffer at 37 degrees C, and gassed with O2 (95%) and CO2 (5%). Contractile responses were recorded with an isometric transducer in a polygraph (Letica, Spain). Contraction was induced by accumulative doses of acetylcholine (0.1, 0.3, 1, 3, 10 mM) or by electric field stimulation (10 Hz at 2 milliseconds), and accumulative doses of dopamine were added to the bath. Low concentration (0.1-0.3 mM) elicited a small initial contraction, followed by a marked relaxation. Cholinergic contraction was completely reversed at 6 mM of dopamine. This biphasic dopaminergic response was not blocked by incubation with beta2-adrenergic antagonist propranolol (0.1 microM), alpha1-antagonist, terazosin (0.1 mM), alpha2-antagonist, yohimbine (0.1 mM), or by DA2 antagonist metoclopramide (1-8 mM); DA1 antagonist SCH23390 (0.1 microM) produced a sustained increase of basal tone but did not block initial dopaminergic contraction and partially inhibited bronchodilator effect of dopamine. Dopaminergic relaxation in rat trachea is mediated by DA1 rather than by DA2 receptors; and adrenergic receptors are not involved in such dopamine-induced response. Finally, DA1 antagonist SCH23390 exerts intrinsic contractile activity on airway smooth muscle that deserves further research. PMID:20496460

  4. A EVOLUÇÃO DA INDÚSTRIA DE AGROTÓXICOS NO BRASIL DE 2001 A 2007: A EXPANSÃO DA AGRICULTURA E AS MODIFICAÇÕES NA LEI DE AGROTÓXICOS

    Microsoft Academic Search

    Fabio Henrique Bittes Terra; Victor Manoel Pelaez

    2008-01-01

    Entre os anos 2001\\/2007, a agricultura nacional cresceu a taxas extraordinárias, superiores às dos outros setores da economia. Este excelente desempenho da agricultura nacional ocorreu sem que existisse um aparato de políticas públicas para fomentá-lo. Desta forma, o desempenho da agricultura favoreceu a atuação de grupos de pressão sobre o marco regulatório dos agrotóxicos, no qual segmentos do setor agrícola

  5. 76 FR 12627 - Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 42, DA 42 NG, and DA 42 M-NG...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ...2120-AA64 Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 42...in-flight loss of a rear passenger door on Diamond aeroplanes, the majority of which were...because of damage found on the hinge. Diamond Aircraft Industries conducted...

  6. 76 FR 27861 - Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 42, DA 42 NG, and DA 42 M-NG...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-13

    ...2120-AA64 Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 42...in-flight loss of a rear passenger door on Diamond aeroplanes, the majority of which were...because of damage found on the hinge. Diamond Aircraft Industries conducted...

  7. Overview of ATLAS PanDA Workload Management

    SciTech Connect

    Maeno T.; De K.; Wenaus T.; Nilsson P.; Stewart G. A.; Walker R.; Stradling A.; Caballero J.; Potekhin M.; Smith D.

    2011-01-01

    The Production and Distributed Analysis System (PanDA) plays a key role in the ATLAS distributed computing infrastructure. All ATLAS Monte-Carlo simulation and data reprocessing jobs pass through the PanDA system. We will describe how PanDA manages job execution on the grid using dynamic resource estimation and data replication together with intelligent brokerage in order to meet the scaling and automation requirements of ATLAS distributed computing. PanDA is also the primary ATLAS system for processing user and group analysis jobs, bringing further requirements for quick, flexible adaptation to the rapidly evolving analysis use cases of the early datataking phase, in addition to the high reliability, robustness and usability needed to provide efficient and transparent utilization of the grid for analysis users. We will describe how PanDA meets ATLAS requirements, the evolution of the system in light of operational experience, how the system has performed during the first LHC data-taking phase and plans for the future.

  8. Geomagnetic observations on tristan da cunha, south atlantic ocean

    USGS Publications Warehouse

    Matzka, J.; Olsen, N.; Maule, C.F.; Pedersen, L.W.; Berarducci, A.M.; Macmillan, S.

    2009-01-01

    Few geomagnetic ground observations exist of the Earth's strongest core field anomaly, the South Atlantic Anomaly (SAA). The geomagnetic repeat station on the island Tristan da Cunha, located half-way between South Africa and South America at 37?? 05' S, 12?? 18' W, is therefore of crucial importance. We have conducted several sets of repeat station measurements during magnetically quiet conditions (Kp 2o or less) in 2004. The procedures are described and the results are compared to those from earlier campaigns and to the predictions of various global field models. Features of the local crustal bias field and the solar quiet daily variation are discussed. We also evaluate the benefit of continuous magnetic field recordings from Tristan da Cunha, and argue that such a data set is a very valuable addition to geomagnetic satellite data. Recently, funds were set up to establish and operate a magnetometer station on Tristan da Cunha during the Swarm magnetic satellite mission (2011-2014).

  9. PanDA's Role in ATLAS Computing Model Evolution

    E-print Network

    Maeno, T; The ATLAS collaboration

    2014-01-01

    During Run 1 at the Large Hadron Collider from 2009-2013, the ATLAS experiment successfully met the computing challenge of accumulating, managing and analyzing a volume of data now exceeding 140 PB, processed at over 100 sites around the world, and accessed by thousands of physicists. This accomplishment required nimbleness and flexibility in the distributed computing infrastructure, both hardware and software, as the operational computing model evolved during the run based on experience. A critical enabler for this evolution was PanDA, the ATLAS workload management system used for production and distributed analysis. PanDA's capabilities were utilized and extended to dynamically and intelligently distribute data and processing workloads across ATLAS resources based on data popularity and resource availability, thereby 'flattening' an originally hierarchical computing model, in order to use resources more efficiently. A new round of PanDA development now taking place will continue to evolve the model for bett...

  10. Um estudo espectrofotométrico da variável cataclísmica V3885 Sgr

    NASA Astrophysics Data System (ADS)

    Ribeiro, F. M. A.; Diaz, M. P.

    2003-08-01

    Variáveis Cataclísmicas são sistemas binários cerrados compostos de uma anã vermelha que transfere matéria para uma anã branca, em sistemas não magnéticos ocorre a formação de um disco de acresção em torno da anã branca. V3885 Sgr é uma variável cataclísmica classificada como sendo do tipo nova-like. É apresentado um estudo espectrofotométrico de V3885 Sgr de alta resolução temporal feito na região do visível. A região observada é centrada em Ha e abrange também a linha de HeI 6678. O primeiro resultado obtido neste estudo é a determinação do período orbital a partir de medidas da velocidade radial da linha de Ha como sendo 0,20716071(22) dias, resolvendo inconsistências quanto a esse valor na literatura e definindo uma efeméride a longo prazo para o sistema. Com este período e as medidas de velocidade radial do perfil de linha de Ha foi construído um diagrama de massas, através do qual restringimos as massas das componentes estelares do sistema e limitamos a inclinação orbital do sistema. Foram construídos diagramas de Greenstein para as linhas de Ha e HeI, onde os espectros médios em cada intervalo de fase são representados lado a lado em escala de cinza, indicando a existência de uma emissão intensa proveniente da parte posterior do disco. A partir da tomografia Doppler obtivemos perfis de emissividade radial para o disco tanto para a linha de Ha como para HeI. Os resultados obtidos são comparados com os de outros sistemas estudados com a mesma técnica. Serão apresentados também resultados da tomografia de flickering para o sistema.

  11. The Potential da Vinci in All of Us

    NSDL National Science Digital Library

    Andrew Petto

    2009-02-01

    The study of the human form is fundamental to both science and art curricula. For vertebrates, perhaps no feature is more important than the skeleton to determine observable form and function. As Leonard da Vinci's famous Proportions of the Human Figure (Virtruvian Man) illustrates, the size, shape, and proportions of the human body are defined by bones and their articulations. In this unit that focuses on the human skeleton, students are introduced to these concepts by asking them both to study da Vinci's drawing and build their own model of the human skeleton. Units on animal camouflage and architecture are also presented to further support the art and science connection.

  12. COMPORTAMENTO MORFOLGICO DA PRAIA DO RIO DAS PACAS, FLORIANPOLIS SC BRASIL

    E-print Network

    Paris-Sud XI, Université de

    COMPORTAMENTO MORFOLÓGICO DA PRAIA DO RIO DAS PACAS, FLORIANÓPOLIS ­ SC ­ BRASIL Fábio Nór Güttler Morfológico da Praia do Rio das Pacas, Florianópolis ­ SC ­ Brasil 73 PerCursos, Florianópolis, v. 8, n. 2, p

  13. 76 FR 37684 - Airworthiness Directives; Diamond Aircraft Industries GmbH Model (Diamond) DA 40 Airplanes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-28

    ...RIN 2120-AA64 Airworthiness Directives; Diamond Aircraft Industries GmbH Model (Diamond) DA 40 Airplanes Equipped With Certain Cabin...found during maintenance inspections of the Diamond Model DA 40 airplanes equipped with a...

  14. FUSIONE NUCLEARE FREDDA da Fleischmann & Pons all'E-Cat di Rossi

    E-print Network

    Bier, Martin

    'Università dello Utah. Stanley Pons (1943) ora originario di Valdese, North Carolina 1 FUSIONE NUCLEARE FREDDA da Fleischmann & Pons all'E-Cat di Rossi di Martin Bier Sono trascorsi ventidue anni da quando S. Pons e M. Fleischmann

  15. Second Life: contextualização e inserção social do ensino da informática

    Microsoft Academic Search

    Leonel Morgado

    2008-01-01

    Resumo - Desde 2006, realizam-se na UTAD ensaios de utilização do mundo virtual Second Life® no ensino de programação de computadores. Nestes dois anos foram identificados problemas no uso da plataforma para este fim, mas também vantagens, nem sempre provenientes dos locais esperados: a imersão social e cultural dos alunos foi factor importante de compreensão dos conceitos informáticos. A imersão

  16. Seo 312 Reitoria /Tcnico-Administrativos Local: Auditrio da Reitoria

    E-print Network

    Floeter, Sergio Ricardo

    VALENTIM BRAZ REITORIA-servidor 312 ALEXANDRE GAVA MENEZES REITORIA-servidor 312 ALEXANDRE PEDRO OLIVEIRA DIAS REITORIA-servidor 312 ANDREA FIGUEIREDO LEAO GRANTS REITORIA-servidor 312 ANDREIA ALVES DOS SANTOS-servidor 312 ARAQUIRI BOTELHO RODRIGUES REITORIA-servidor 312 ARI ABILIO DA SILVA REITORIA-servidor 312 ARI

  17. EXTRATIVISMO DA CARNAÚBA: O DESAFIO DE ESTIMAR OS RESULTADOS ECONÔMICOS

    Microsoft Academic Search

    Maria Odete Alves; Jackson Dantas Coelho

    2008-01-01

    O objetivo principal deste trabalho foi estimar custos e lucro líquido nas etapas de campo (incluindo a elaboração de cera de origem) do extrativismo da carnaúba. A coleta dos dados ocorreu ao longo dos anos de 2005 e 2006, por meio de entrevistas abertas e observação de campo, ocasião em que se realizou um diagnóstico amplo do setor. A motivação

  18. Theoretical models for asteroseismology of DA white dwarf stars

    Microsoft Academic Search

    P. A. Bradley

    1996-01-01

    Because white dwarfs are the most common end state of stellar evolution, determining their internal structure will yield many clues about the final stages of stellar evolution and the physics of matter under extreme conditions. We present the results of our parametric survey of evolutionary models of compositionally stratified white dwarfs with hydrogen surface layers (DA white dwarfs) and provide

  19. Ministrio da Educao Centro Federal de Educao Tecnolgica do Paran

    E-print Network

    Pimentel, Andrey Ricardo

    ........................................................................................................... 13 2.2.2 Medidas para o cálculo da independência funcional.................................................... 15 2.2.3 Hierarquia funcional e decomposição funcional..................................................... 22 2.4.2 Decomposição funcional

  20. DA Associate Program -AeS Proposal Ongoing development

    E-print Network

    Southampton, University of

    DA Associate Program - AeS Proposal Ongoing development Aryldo G Russo Jr. AeS Group & Research Institute of State of S~ao Paulo (IPT), agrj@aes.com.br Abstract. I would like to present, by this proposal detailed way an introduction of AeS company, the AeS proposal and pilot project and the expected results. 1

  1. WEIGHT:WEIGHT: DA FORM705, JUN 1998,MAYBE USED

    E-print Network

    de Lijser, Peter

    UNIT USAPA V1.00 WEIGHT: DATE GRADE AGE HEIGHT(IN INCHES) BODY FAT: GO / NO-GO PU RAW SCORE INITIALSWEIGHT:WEIGHT: DA FORM705, JUN 1998,MAYBE USED Data Required by the Privacy Act of 1974 DATE GRADE POINTS NCOIC/OICSIGNATURE COMMENTS BODY COMPOSITION EVENT TIME lbs % GO / NO-GO DATE GRADE AGE HEIGHT

  2. ISSN 0103-9741 Monografias em Cincia da Computao

    E-print Network

    Endler, Markus

    Leagues Alexandre Rocha Duarte Edward Hermann Haeusler Celso Carneiro Ribeiro Sebastián Urrutia. Duarte and Edward H. Haeusler and Celso C. Ribeiro1 and Sebastián Urrutia2 1 Departamento de Ciência da have been re- viewed by Ribeiro and Urrutia [9]. Combinatorial optimization techniques have been ap

  3. A Survey of adaptation systems Keling DA #1

    E-print Network

    Paris-Sud XI, Université de

    1 A Survey of adaptation systems Keling DA #1 , Marc DALMAU #2 , Philippe ROOSE #3 UPPA, LIUPPA@univ-pau.fr Abstract--Development of ubiquitous applications is inherently complex. Adaptation system is a solution for ubiquitous comput- ing. It enhances the efficiency of application by the adaptation of software, facilitates

  4. (Ordem Alfabtica) ALUNA: ANA LUSA SOUZA CASTANHEIRA DA CRUZ (UFRJ)

    E-print Network

    . ROGÉRIO MORAES OLIVEIRA (LAP/CTE), DR. MÁRIO UEDA (LAP/CTE), PROF. DR. CARLOS MOURA NETO (ITA), DRA ORBITAIS DE SATÉLITES LUNARES DEVIDO À DISTRIBUIÇÃO NÃO UNIFORME DE MASSA DA LUA". ORIENTADOR: DR. ANTÔNIO PARA O ÍNDICE Dst". ORIENTADOR: DR. CLÉZIO MARCOS DE NARDIN (CEA/DAE) COLABORADOR: PROF. DR. RODOLPHO

  5. ISSN 0103-9741 Monografias em Cincia da Computao

    E-print Network

    Endler, Markus

    no modelo utilizado pelos sistemas de software. Entretanto, se modelos de nível mais altos fossem adotadosPUC ISSN 0103-9741 Monografias em Ciência da Computação n° 03/10 Estudo sobre Modelos de/10 ISSN: 0103-9741 Editor: Prof. Carlos José Pereira de Lucena Abril, 2010 Estudo sobre Modelos de

  6. ISSN 0103-9741 Monografias em Cincia da Computao

    E-print Network

    Endler, Markus

    Sistema de recomendação: uma abordagem por ltro colaborativo baseado em modelos 1 Dárlinton Barbosa FeresPUC ISSN 0103-9741 Monografias em Ciência da Computação n 19/10 Sistemas de Recomendação: uma abordagem por filtro colaborativo baseado em modelos Dárlinton Barbosa Feres Carvalho Ruy Luiz Milidiú

  7. ISSN 0103-9741 Monografias em Cincia da Computao

    E-print Network

    Endler, Markus

    PUC ISSN 0103-9741 Monografias em Ciência da Computação n° 05/06 IPTV Conceitos, Padrões e Soluções Computação, No. 05/06 ISSN: 0103-9741 Editor: Prof. Carlos José Pereira de Lucena Fevereiro, 2006 IPTV ) ! %& % * & + %& %& 1 >1 , 2 Soluções e provedores de serviço de IPTV 2.1 Soluções : %) % %) % 6

  8. DIGESTORE ANAEROBICO DA LABORATORIO DEL CENTRO DI RICERCA SULLE BIOMASSE

    Microsoft Academic Search

    G. Bidini; F. Cotana; C. Buratti; F. Fantozzi; I. Costarelli

    La produzione di metano attraverso la digestione anaerobica a partire da biomasse residuali sta assumendo un ruolo di crescente importanza nel panorama energetico mondiale. Tuttavia pochi sono i dati disponibili in Letteratura sui bilanci di massa ed energia per il processo di digestione anaerobica, che sono invece di grande interesse sia per condurre studi di fattibilità che per eseguire una

  9. Assessing “Western” Mindfulness Among Thai Therav?da Buddhist Monks

    Microsoft Academic Search

    Michael S. Christopher; Varinthorn Christopher; Sukjai Charoensuk

    2009-01-01

    Mindfulness has its roots in Eastern contemplative traditions and is rapidly gaining popularity in Western psychology. However, questions remain regarding the validity of Western operationalizations of mindfulness. Therefore, the purpose of this study was to assess the applicability of several Western mindfulness measures among a sample of Thai Therav?da Buddhist monks. Twenty-four monks recruited from Buddhist temples in Thailand participated

  10. Galapagos sharks (Carcharhinus galapagensis) at the Bassas da

    E-print Network

    Miami, University of

    Galapagos sharks (Carcharhinus galapagensis) at the Bassas da India atoll: first record from Introduction The Galapagos shark, Carcharhinus galapagensis,1 is circum- tropical in its distribution; however and species identification During October 2003, a shark diversity survey was conducted at several locations

  11. Programa Intensivo de Lngua Portuguesa e Cultura Brasileira da UFMG

    E-print Network

    Chaimowicz, Luiz

    Programa Intensivo de Língua Portuguesa e Cultura Brasileira da UFMG Intensive Program no exterior, interessados em aperfeiçoar seus conhecimentos de Língua Portuguesa e Cultura Brasileira. O curso cultura", das autoras: Regina Lúcia Péret Dell'Isola e Maria José Apparecida de Almeida - Editora: UFMG

  12. Redao e Dinmica da Produo Cientfica Carga horria: 30 hs

    E-print Network

    Floeter, Sergio Ricardo

    . Publicação científica. São Paulo, Cultura Acadêmica. Volpato, GL. 2010. Dicas para redação científica. São Paulo, Cultura Acadêmica. Volpato, GL. 2010. Pérodas da redação científica. São Paulo, Cultura Acadêmica. Volpato, GL. 2011. Método lógico para redação científica. São Paulo, Cultura Acadêmica. LITERATURA

  13. PODER JUDICIRIO TRIBUNAL DE JUSTIA DO ESTADO DA BAHIA

    E-print Network

    Maier, Rudolf Richard

    PARA INGRESSO NO CARGO DE JUIZ DE DIREITO SUBSTITUTO EDITAL Nº 12 ­ TJ/BA ­ JUIZ SUBSTITUTO, DE 9 DE Purificação da Silva, na qualidade de Presidente; Desembargador Nilson Soares Castelo Branco; Juiz de Direito Direito Oséias Costa de Sousa; Juíza de Direito Mariana Teixeira Lopes; Bacharel André Luis Guimarães

  14. The DaVinci Project: Multimedia in Art and Chemistry.

    ERIC Educational Resources Information Center

    Simonson, Michael; Schlosser, Charles

    1998-01-01

    Provides an overview of the DaVinci Project, a collaboration of students, teachers, and researchers in chemistry and art to develop multimedia materials for grades 3-12 visualizing basic concepts in chemistry and visual art. Topics addressed include standards in art and science; the conceptual framework for the project; and project goals,…

  15. Leonardo da Vinci and the sinuses of Valsalva.

    PubMed

    Robicsek, F

    1991-08-01

    Recent studies indicate that eddy currents generated by the sinuses of Valsalva play an important role in the physiologic closure of the aortic valve. This process is briefly discussed and evidence is presented that this fact was well known and elaborated upon by the renaissance artist Leonardo da Vinci. This fact is illustrated with his words and drawings. PMID:1863165

  16. COOPERATIVAS COMO FORMA DE ORGANIZAÇÃO DA AGRICULTURA FAMILIAR

    Microsoft Academic Search

    Nadir Paula Da Rosa; Adriano Lago; Silvio Santos Junior; Erica Silva Mendonca

    2008-01-01

    A agricultura familiar desempenha um importante papel socioeconômico na sociedade, proporcionando a permanência do homem no campo, conseqüentemente evitando o êxodo rural, e reduzindo o crescimento dos cinturões da pobreza em torno das cidades a procura de trabalho. O foco central do presente estudo concentra-se em discutir os motivos que levam as pequenas famílias rurais a buscar diferentes maneiras de

  17. Da universidade para o mercado de trabalho em onze pases

    E-print Network

    Instituto de Sistemas e Robotica

    Universia está a ser lançado em várias instituições de ensino superior portuguesas. Rede ibero-americana regista por mês 195 mil ofertas ANA BELA FERREIRA Desde quinta-feira que os 23 mil alunos da Universidade a pró-rei- tora, Ana Nunes de Almeida. Ao aderir a esta plataforma, que con- centra não só ofertas

  18. MICROPROPAGAÇÃO DA AROEIRA (Myracrodruon urundeuva Fr. All) 1

    Microsoft Academic Search

    MIGUEL WANDERLEY DE ANDRADE; JOSÉ MAGNO; QUEIROZ LUZ; ARY SANTANA LACERDA; PEDRO RENATO A. DE

    RESUMO - A aroeira (Myracrodruon urundeuva Fr. All) é uma Anacardiaceae lenhosa que tem sido usada de forma predatória pela qualidade de sua madeira e pelo uso med i- cinal de sua casca desprovida de súber, por meio da qual se fabrica antiinflamatório. O objetivo deste trabalho foi o e s- tabelecimento \\

  19. Autoantibody to the leucine zipper region of 52 kDa Ro/SSA binds native 60 kDa Ro/SSA: identification of a tertiary epitope with components from 60 kDa Ro/SSA and 52 kDa Ro/SSA.

    PubMed

    Kurien, B T; Chambers, T L; Thomas, P Y; Frank, M B; Scofield, R H

    2001-03-01

    Anti-Ro (or SSA) is found in the sera of patients with autoimmune rheumatic illnesses. All patients with anti-Ro defined by precipitation bind a 60 000 Da antigen (60 kDa Ro), whereas some patients also bind a 52 000 Da molecule (52 kDa Ro). In general, antibody binding is directed against native 60 kDa Ro and denatured 52 kDa Ro. The mechanism by which anti-52 kDa Ro arises in the setting of anti-60 kDa Ro is unknown. Conflicting data exist as to the existence of a physical interaction between the two proteins in cells and as to cross-reacting antibodies. Antibodies were affinity purified from a peptide within the leucine zipper region of 52 kDa Ro. These purified antibodies binding the 197-207 peptide from 52 kDa Ro (anti-52LZ) bound native 60 kDa Ro as well as denatured 52 kDa Ro. In addition, anti-52LZ also bound up to four regions from the sequence of 60 kDa Ro and a single conformational epitope of 60 kDa Ro. Thus, these primary sites represent components of the tertiary epitope. We hypothesized that if this was the case, these peptides making up a tertiary epitope would show molecular interaction. In fact, peptides from 60 kDa Ro have a molecular interaction with the 52 kDa Ro peptide as well as full-length 52 kDa Ro when assessed by surface plasmon resonance. The leucine-zipper region peptide from 52 kDa Ro bound three of the four peptides from 60 kDa Ro. These data suggest that these two molecular species, 60 and 52 kDa Ro, form a conformational epitope. This relationship may explain why anti-52 kDa Ro is found in association with anti-60 kDa Ro. PMID:11251884

  20. Novel 28-kDa secretory protein from rat olfactory epithelium

    Microsoft Academic Search

    I. V. Peshenko; V. I. Novoselov; V. A. Evdokimov; Yu. V. Nikolaev; T. M. Shuvaeva; V. M. Lipkin; E. E. Fesenko

    1996-01-01

    We have isolated a novel secretory 28-kDa protein which is an abundant component of the rat olfactory mucosa. The partial sequence of the 28-kDa protein has been determined. The amino acid sequence of the 28-kDa protein is similar to that of non-selenium glutathione peroxidase from bovine ciliary body. The 28-kDa protein catalyzed decomposition of the hydrogen peroxide as well as

  1. 40486 Dirio da Repblica, 2. srie --N. 145 --28 de Julho de 2010 Aviso n. 14939/2010

    E-print Network

    Instituto de Sistemas e Robotica

    . . . . . . . . . . . . . . . . . . . . . . . . . a) Patrícia Alexandra da Silva Clemente . . . . . . . . . . . . . . . . a) Pedro Miguel T. da Silva Dias . . . . . . . . . . . . . . . . . . . . . . . . a) Ana Carina Estêvão Amaro . . . . . . . . . . . . . . . . . . . . b) Sandra Isabel Almeida Rodrigues . . . . . . . . . . . . . . . . . . . b) Susana Marina Patrício

  2. Os determinantes da desigualdade de renda no Brasil: Luta de classes ou heterogeneidade educacional?

    Microsoft Academic Search

    Francisco de Hollanda Guimarães Ferreira

    2000-01-01

    Este trabalho considera a questão: quais os principais determinantes da desigualdade de renda no Brasil? Após lembrar a importância da questão para a nossa economia, o artigo sugere um arcabouço genérico para categorizar os determinantes da distribuição de renda, baseado em cinco grupos de fatores: caraterísticas natas dos indivíduos; suas características adquiridas; o papel do mercado de trabalho; o papel

  3. MÉTODOS PARA DETERMINAÇÃO DA DENSIDADE BÁSICA DE CAVACOS PARA CONÍFERAS E FOLHOSAS

    Microsoft Academic Search

    Celso Edmundo; Bochetti Foelkel; Maria Aparecida Mourão Brasil; Luiz Ernesto; George Barrichelo

    1 - INTRODUÇÃO A densidade da madeira é uma característica complexa resultante da combinação de diversos fatôres. Existem inúmeros trabalhos mostrando sua relação com as dimensões das fibras, particularmente espessura da parede, volume dos vasos e parênquimas, proporção entre madeira primaveril e outonal, e arranjo dos elementos anatômicos. Êste assunto tem sido intensivamente estudado para as coníferas, porém para as

  4. PREVISÃO DA VAZÃO AFLUENTE MENSAL DO RIO SÃO FRANCISCO USANDO-SE REDES DE ELMAN

    Microsoft Academic Search

    Luiz Biondi Neto; Pedro Henrique Gouvêa Coelho; Luís Chiganer; Lídia Angulo Meza; Luiz Palmeira Monteiro

    2005-01-01

    Resumo: Este artigo apresenta resultados de previsão da vazão afluente mensal do Rio São Francisco, que alimenta a usina de Sobradinho, usando-se redes neurais de Elman (RNA). As redes neurais de Elman utilizadas foram preparadas com o objetivo de receber como entrada amostras da série temporal da vazão afluente do Rio São Francisco deslocadas mês a mês. Para tal, nas

  5. Listaxe provisoria de persoas admitidas da convocatoria '[Cod. 652] Bolsas de colaboracin en tarefas bibliogrficas

    E-print Network

    Fraguela, Basilio B.

    1. 2. 3. 4. 5. 6. 7. Listaxe provisoria de persoas admitidas da convocatoria '[Cod. 652] Bolsas de presentación de solicitudes para a selección de bolseiros da convocatoria '[Cod. 652] Bolsas de colaboración en provisoria de persoas admitidas da convocatoria '[Cod. 613] Bolsas de colaboración en tarefas bibliográficas

  6. Listaxe definitiva de persoas admitidas da convocatoria '[Cod. 652] Bolsas de colaboracin en tarefas bibliogrficas

    E-print Network

    Fraguela, Basilio B.

    1. 2. 3. 4. 5. 6. 7. Listaxe definitiva de persoas admitidas da convocatoria '[Cod. 652] Bolsas de presentación de emendas e reclamacións para a selección de bolseiros da convocatoria '[Cod. 652] Bolsas de admitidas da convocatoria '[Cod. 613] Bolsas de colaboración en tarefas bibliográficas - Facultade de

  7. Sociedade Brasileira de Qumica ( SBQ) Reunio Anual da Sociedade Brasileira de Qumica

    E-print Network

    Ferreira, Márcia M. C.

    . Maiara da S. Santos 1 * (IC), Glaucia B. Alcantara 1 (PG), Andersson Barison 1 (PG), Luís P. S. Santos 1 Barison, A.; Ferreira, A. G.; Toledo, J. F. F.; Ferreira, M.M.C. 27ª Reunião anual da Sociedade BrasileiraSociedade Brasileira de Química ( SBQ) 28a Reunião Anual da Sociedade Brasileira de Química

  8. Facultade de Ciencias da Educacin Mster Universitario en Psicopedagoga por la Universidad de A Corua

    E-print Network

    Fraguela, Basilio B.

    Facultade de Ciencias da Educación Máster Universitario en Psicopedagogía por la Universidad de Verificación Facultad de Ciencias de la Educación Universidad de A Coruña Año 2013 #12;Facultade de Ciencias da Ciencias da Educación Máster Universitario en Psicopedagogía por la Universidad de A Coruña Página 3 de 134

  9. Comercialização de carqueja por ervateiros da zona central de Pelotas, Rio Grande do Sul

    Microsoft Academic Search

    Gustavo Heiden; Leila Macias; Vera Lucia Bobrowski; João Ricardo Vieira Iganci

    RESUMO A venda de carqueja (Baccharis L. seção Caulopterae DC., Asteraceae), é uma atividade comum entre ervateiros da zona central de Pelotas, bem como a procura e uso desta planta pelos consumidores. Com o objetivo de caracterizar a comercialização e o consumo de carqueja, foram entrevistados ervateiros da Zona Central da cidade de Pelotas, localizada no Sul do Estado do

  10. Distance-Adaptive Routing and Spectrum Assignment (DA-RSA) in Rings

    E-print Network

    Distance-Adaptive Routing and Spectrum Assignment (DA-RSA) in Rings Sahar Talebi, Iyad Katib that the the distance- adaptive routing and spectrum assignment (DA-RSA) problem in mesh networks is a special case of a multiprocessor scheduling problem. We then develop a suite of efficient and effective DA-RSA algorithms

  11. 40 CFR 60.44Da - Standard for nitrogen oxides (NOX).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 6 2010-07-01 2010-07-01 false Standard for nitrogen oxides (NOX). 60.44Da Section 60.44Da Protection...Commenced After September 18, 1978 § 60.44Da Standard for nitrogen oxides (NOX ). (a) On and after the date on...

  12. 40 CFR 60.44Da - Standards for nitrogen oxides (NOX).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...7 2014-07-01 2014-07-01 false Standards for nitrogen oxides (NOX). 60.44Da Section 60.44Da Protection...Utility Steam Generating Units § 60.44Da Standards for nitrogen oxides (NOX ). (a) Except as provided in...

  13. 40 CFR 60.44Da - Standards for nitrogen oxides (NOX).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...7 2013-07-01 2013-07-01 false Standards for nitrogen oxides (NOX). 60.44Da Section 60.44Da Protection...Utility Steam Generating Units § 60.44Da Standards for nitrogen oxides (NOX ). (a) Except as provided in...

  14. 40 CFR 60.44Da - Standards for nitrogen oxides (NOX).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...7 2012-07-01 2012-07-01 false Standards for nitrogen oxides (NOX). 60.44Da Section 60.44Da Protection...Utility Steam Generating Units § 60.44Da Standards for nitrogen oxides (NOX ). (a) Except as provided in...

  15. 40 CFR 60.44Da - Standard for nitrogen oxides (NOX).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 6 2011-07-01 2011-07-01 false Standard for nitrogen oxides (NOX). 60.44Da Section 60.44Da Protection...Commenced After September 18, 1978 § 60.44Da Standard for nitrogen oxides (NOX ). (a) On and after the date on...

  16. AVALIAÇÃO DA EDUCAÇÃO AMBIENTAL NO GERENCIAMENTO DOS RESÍDUOS SÓLIDOS NO CAMPUS DA UNIVERSIDADE ESTADUAL DE FEIRA DE SANTANA

    Microsoft Academic Search

    Sandra Maria Furiam; Wanda Risso Günther

    RESUMO — O trabalho apresenta uma avaliação do projeto de Educa- ção Ambiental voltado para o Gerenciamento dos Resíduos Sólidos ge- rados no campus da UEFS. O projeto foi implantado em 1992 tendo como princípio a coleta seletiva e a valorização dos resíduos secos e a compostagem do resíduo orgânico. Foi realizada uma pesquisa documental e entrevis- tas com o

  17. 75 FR 75868 - Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 40 and DA 40F Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-07

    ...2120-AA64 Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 40...information identified in this AD, contact Diamond Aircraft Industries GmbH, N.A. Otto-Stra...43 2622 26780; e-mail: office@diamond-air.at; Internet:...

  18. Application of slingshot model to the giant radio galaxy DA240 (Brief : DA 240 in slingshot model)

    E-print Network

    Muthumeenal, S

    2010-01-01

    We attempt a slingshot model interpretation of the unusual association of some 1&1/3 dozen nonstellar galaxian objects around the parent optical galaxy of the giant radio galaxy DA 240 (= 0748.6+55.8 (J2000)). Similar interpretation may be possible for another large radio galaxy 3C 31 (= NGC 383 = 0104.6+32.1 (1950.0)).

  19. Crescimento ponderal de filhotes de tartaruga gigante da Amazônia (Podocnemis expansa) submetidos a tratamento com rações isocalóricas contendo diferentes níveis de proteína bruta

    Microsoft Academic Search

    Vinicius Augusto Sá; Leonardo C. Quintanilha; Gustavo Eduardo Freneau; Vera Lucia Ferreira Luz; Arcádio de Los Reyes Borja; Paulo César Silva

    2004-01-01

    RESUMO - A criação de Podocnemis expansa, a tartaruga-da-amazônia, com finalidade comercial foi implantada no Brasil em 1992. Contudo, muitas questões acerca do manejo, da nutrição, da sanidade e, principalmente, da reprodução ainda são obscuras. Visando contribuir para o desenvolvimento de uma metodologia alimentar da espécie, objetivou-se testar diferentes níveis de proteína da dieta. Uma amostra de 480 animais neonatos

  20. Functions of the 126- and 183-kDa proteins of tobacco mosaic virus.

    PubMed

    Lewandowski, D J; Dawson, W O

    2000-05-25

    Tobacco mosaic virus produces two proteins that contain domains similar to the methyltransferase (MT) and helicase (HEL)-like domains of the replicase-associated proteins of other RNA viruses. The more abundant 126-kDa protein contains only the MT and HEL-like domains, whereas the 183-kDa readthrough protein additionally contains the polymerase domain. We examined the functions of these proteins by constructing a bipartite system to express the 126- and 183-kDa proteins from separate RNAs. Mutants expressing the 183-kDa protein recognized promoters for negative- and positive-stranded RNA synthesis, transcribed subgenomic mRNAs, capped RNAs, synthesized proteins, moved cell to cell within the plant, and replicated defective RNAs (dRNAs). The principal function of the 126-kDa protein was to increase the rate of replication approximately tenfold. The 126-kDa protein appeared to function primarily in cis, and production of the 126-kDa protein in trans did not enhance replication of the helper virus. dRNAs producing a functional 126-kDa protein were replicated efficiently by helper viruses that produced only the 183-kDa protein but not by wild-type virus, suggesting that efficient replication required the 183-kDa protein to form a heterodimer with the 126-kDa protein already bound to the target dRNA. PMID:10814574

  1. The Da Vinci code dynamically de-coded.

    PubMed

    Cohen, Mariam

    2005-01-01

    The novel The Da Vinci Code, by Dan Brown has been on best-seller lists for over two years. An examination of Brown's previous novels reveals a well-designed plot line shared by all four novels that not only makes them good "thrillers" but also creates a mythological structure to the novels that draws on common unconscious fantasies in the same way that fairy tales do. One aspect of this mythological structure is the use of evil conspiracies (and benign ones as well) for the protagonist to overcome. In addition, The Da Vinci Code presents a religious theme involving legends about Mary Magdalene. This theme touches on the role of a feminine aspect to divinity in allowing for an erotic connection with the divine. PMID:16448349

  2. DaVinci's Mona Lisa entering the next dimension.

    PubMed

    Carbon, Claus-Christian; Hesslinger, Vera M

    2013-01-01

    For several of Leonardo da Vinci's paintings, such as The Virgin and Child with St Anne or the Mona Lisa, there exist copies produced by his own studio. In case of the Mona Lisa, a quite exceptional, rediscovered studio copy was presented to the public in 2012 by the Prado Museum in Madrid. Not only does it mirror its famous counterpart superficially; it also features the very same corrections to the lower layers, which indicates that da Vinci and the 'copyist' must have elaborated their panels simultaneously. On the basis of subjective (thirty-two participants estimated painter-model constellations) as well as objective data (analysis of trajectories between landmarks of both paintings), we revealed that both versions differ slightly in perspective. We reconstructed the original studio setting and found evidence that the disparity between both paintings mimics human binocular disparity. This points to the possibility that the two Giocondas together might represent the first stereoscopic image in world history. PMID:24303752

  3. Kaonic Atoms at DA?NE — the Siddharta Experiment

    NASA Astrophysics Data System (ADS)

    Zmeskal, J.; Bazzi, M.; Beer, G.; Bombelli, L.; Bragadireanu, A. M.; Bühler, P.; Cargnelli, M.; Curceanu Petrascu, C.; Fiorini, C.; Guaraldo, C.; Hayano, R. S.; Iliescu, M.; Ishiwatari, T.; Iwasaki, M.; Kienle, P.; Longoni, A.; Lucherini, V.; Marton, J.; Nikolics, K.; Okada, S.; Pietreanu, D.; Ponta, T.; Vidal, A. Romero; Sandri, P. L.; Scordo, A.; Sirghi, D. L.; Sirghi, F.; Suzuki, K.; Tatsuno, H.; Doce, O. Vázquez; Widmann, E.

    With precision X-ray spectroscopy of kaonic hydrogen at the DA?NE electron-positron collider at Laboratori Nazionali di Frascati the chiral symmetry breaking scenario in the strangeness sector will be investigated by studying the K-p s-wave interaction at threshold. This is possible by observing the strong interaction induced shift and width of the 1s state in kaonic hydrogen atoms. The results of the first measurement at LNF with DEAR (DA?NE Exotic Atom Research) will be given and the new SIDDHARTA (Silicon Drift Detector for Hadronic Atom Research with Timing Application) project will be described, which is aiming at a substantial improvement of the preceding DEAR result.

  4. [Lobectomy for lung cancer using the Da Vinci surgical system].

    PubMed

    Nakamura, Hiroshige

    2014-05-01

    Robot-assisted surgery using the da Vinci surgical system has attracted attention because of excellent operability without shaking by joint forceps under the clear vision of a three-dimensional high-definition camera in lung cancer surgery. Although this form of advanced medical care is not yet approved for insurance coverage, it is at the stage of clinical research and expected to be useful in hilar exposure, lymph node dissection, and suturing of the lung parenchyma or bronchus. Lung cancer surgery with the da Vinci system has the advantage of combining thoracotomy and minimally invasive surgery in video-assisted thoracic surgery. However, safety management, education, and significant cost are problems to be resolved. Several important issues such as sharing knowledge and technology of robotic surgery, education, training, development of new instruments, and acquisition of advanced medical insurance are discussed for the future development of robotic surgical systems. PMID:24946522

  5. TA-DA: a Tool for Astrophysical Data Analysis

    E-print Network

    Da Rio, Nicola

    2012-01-01

    We present TA-DA, a new software aimed at greatly simplify and improve the analysis of stellar photometric data in comparison with theoretical models, and allow the derivation of stellar parameters from multi-band photometry. Its flexibility allows one to address a number of such problems: from the interpolation of stellar models, or sets of stellar physical parameters in general, to the computation of synthetic photometry in arbitrary filters or units; from the analysis of observed color-magnitude diagrams, to a Bayesian derivation of stellar parameters (and extinction) based on multi-band data. TA-DA is available as a pre-compiled IDL widget-based application; its graphical user interface makes it considerably user-friendly. In this paper we describe the software and its functionalities.

  6. TA-DA: A TOOL FOR ASTROPHYSICAL DATA ANALYSIS

    SciTech Connect

    Da Rio, Nicola [European Space Agency, Keplerlaan 1, 2200-AG Noordwijk (Netherlands); Robberto, Massimo, E-mail: ndario@rssd.esa.int [Space Telescope Science Institute, 3700 San Martin Dr., Baltimore, MD 21218 (United States)

    2012-12-01

    We present the Tool for Astrophysical Data Analysis (TA-DA), a new software aimed to greatly simplify and improve the analysis of stellar photometric data in comparison with theoretical models, and allow the derivation of stellar parameters from multi-band photometry. Its flexibility allows one to address a number of such problems: from the interpolation of stellar models, or sets of stellar physical parameters in general, to the computation of synthetic photometry in arbitrary filters or units; from the analysis of observed color-magnitude diagrams to a Bayesian derivation of stellar parameters (and extinction) based on multi-band data. TA-DA is available as a pre-compiled Interactive Data Language widget-based application; its graphical user interface makes it considerably user-friendly. In this paper, we describe the software and its functionalities.

  7. Improving Security in the ATLAS PanDA System

    NASA Astrophysics Data System (ADS)

    Caballero, J.; Maeno, T.; Nilsson, P.; Stewart, G.; Potekhin, M.; Wenaus, T.

    2011-12-01

    The security challenges faced by users of the grid are considerably different to those faced in previous environments. The adoption of pilot jobs systems by LHC experiments has mitigated many of the problems associated with the inhomogeneities found on the grid and has greatly improved job reliability; however, pilot jobs systems themselves must then address many security issues, including the execution of multiple users' code under a common 'grid' identity. In this paper we describe the improvements and evolution of the security model in the ATLAS PanDA (Production and Distributed Analysis) system. We describe the security in the PanDA server which is in place to ensure that only authorized members of the VO are allowed to submit work into the system and that jobs are properly audited and monitored. We discuss the security in place between the pilot code itself and the PanDA server, ensuring that only properly authenticated workload is delivered to the pilot for execution. When the code to be executed is from a 'normal' ATLAS user, as opposed to the production system or other privileged actor, then the pilot may use an EGEE developed identity switching tool called gLExec. This changes the grid proxy available to the job and also switches the UNIX user identity to protect the privileges of the pilot code proxy. We describe the problems in using this system and how they are overcome. Finally, we discuss security drills which have been run using PanDA and show how these improved our operational security procedures.

  8. RISCHIO BIOLOGICO DA VIRUS EMATICI IN OPERATORI SANITARI

    Microsoft Academic Search

    M. A. Di Benedetto; F. Vitale; L. Cannova; D. Cabibi

    Introduzione Negli ultimi anni l'attenzione del mondo scientifico per il rischio infettivo occupazionale ha ricevuto un nuovo impulso in conseguenza dell'epidemia da virus dell'Immunodeficienza Acquisita (HIV). Tale interesse, infatti , centrato fino a qualche decennio fa sul rischio di tra- smissione del virus dell'epatite B, era diminuito grazie alla prevenzione di questa infezione con l'introduzione della vaccinazione. Dopo il primo

  9. A novel 35 kDa frog liver acid metallophosphatase

    Microsoft Academic Search

    Agata Szalewicz; Barbara Radomska; Barbara Strzelczyk; Aleksandra Kubicz

    1999-01-01

    The lower molecular weight (35 kDa) acid phosphatase from the frog (Rana esculenta) liver is a glycometalloenzyme susceptible to activation by reducing agents and displaying tartrate and fluoride resistance. Metal chelators (EDTA, 1,10-phenanthroline) inactivate the enzyme reversibly in a time- and temperature-dependent manner. The apoenzyme is reactivated by divalent transition metal cations, i.e. cobalt, zinc, ferrous, manganese, cadmium and nickel

  10. EFEITOS DA GEADA NA MADEIRA DE Eucalyptus saligna

    Microsoft Academic Search

    E. S. B. FERRAZ; A. R. COUTINHO

    RESUMO - Numa área de reflorestamento com Eucalyptus saligna com nove anos de idade foram selecionadas 235 árvores divididas em cinco classes de diâmetro, caracterizando toda a população. Segundo os registros meteorológicos, uma geada ocorreu no segundo ano ap6s o plantio. Procurou-se então verificar os efeitos da geada na madeira das árvores amostradas, procurando-se distinguir as dominantes das dominadas. As

  11. TUTORIAL DE PESQUISA BIBLIOGRTUTORIAL DE PESQUISA BIBLIOGRTUTORIAL DE PESQUISA BIBLIOGRTUTORIAL DE PESQUISA BIBLIOGRFICAFICAFICAFICA Este tutorial faz parte da programao de treinamentos da Biblioteca de Cincias daBiblioteca de Cincias daBiblioteca de Cinc

    E-print Network

    Paraná, Universidade Federal do

    SaSaSaúúúúdededede ­­­­ SdSdSdSd da Universidade Federal do Paranda Universidade Federal do Paranda Universidade Federal do Paranda Universidade Federal do Paranáááá.... Serve como material de apoio e não possui fins lucrativos 11111111 3.1 Online Search3.1 Online Search3.1 Online Search3.1 Online Search ---- Pesquisa Online

  12. Fatores Determinantes da Escolha de Cursos de Educação Continuada

    Microsoft Academic Search

    Scott Brusa Mesquita

    Resumo Este artigo discute os principais fatores considerados pelos executivos na escolha entre diferentes possibilidades de cursos de extensão. Baseia-se em uma pesquisa realizada com 150 estudantes de cursos de extensão. Após a análise dos dados, tornou-se claro que o prestígio da escola, a aplicabilidade do conteúdo ministrado e o foco teórico\\/prático do curso são fatores essenciais para a escolha

  13. Infraestrut. Financiamiento publico procedente da Unin Europea X X

    E-print Network

    Fraguela, Basilio B.

    I+D+i Docencia Relac.Soc. Xestión Infraestrut. Financiamiento publico procedente da Unión Europea X X Aposta dos poderes públicos polo investimento en I+D+i X X Estabilidade do financiamento público autonómico para o período 2005-10 X X X X Demanda tecnolóxica por parte do sector empresarial próximo X X X X

  14. Latest Results from Kloe at DA?NE

    NASA Astrophysics Data System (ADS)

    Gauzzi, P.; Ambrosino, F.; Antonelli, A.; Antonelli, M.; Bacci, C.; Beltrame, P.; Bencivenni, G.; Bertolucci, S.; Bini, C.; Bloise, C.; Bocchetta, S.; Bocci, V.; Bossi, F.; Bowring, D.; Branchini, P.; Caloi, R.; Campana, P.; Capon, G.; Capussela, T.; Ceradini, F.; Chi, S.; Chiefari, G.; Ciambrone, P.; Conetti, S.; de Lucia, E.; de Santis, A.; de Simone, P.; de Zorzi, G.; Dell'Agnello, S.; Denig, A.; di Domenico, A.; di Donato, C.; di Falco, S.; di Micco, B.; Doria, A.; Dreucci, M.; Felici, G.; Ferrari, A.; Ferrer, M. L.; Finocchiaro, G.; Fiore, S.; Forti, C.; Franzini, P.; Gatti, C.; Giovannella, S.; Gorini, E.; Graziani, E.; Incagli, M.; Kluge, W.; Kulikov, V.; Lacava, F.; Lanfranchi, G.; Lee-Franzini, J.; Leone, D.; Martini, M.; Massarotti, P.; Mei, W.; Meola, S.; Miscetti, S.; Moulson, M.; Müller, S.; Murtas, F.; Napolitano, M.; Nguyen, F.; Palutan, M.; Pasqualucci, E.; Passeri, A.; Patera, V.; Perfetto, F.; Pontecorvo, L.; Primavera, M.; Santangelo, P.; Santovetti, E.; Saracino, G.; Sciascia, B.; Sciubba, A.; Scuri, F.; Sfiligoi, I.; Spadaro, T.; Testa, M.; Tortora, L.; Valente, P.; Valeriani, B.; Venanzoni, G.; Veneziano, S.; Ventura, A.; Versaci, R.; Xu, G.

    The KLOE experiment has finished its data taking at the e+e- collider DA?NE in Frascati. KLOE has collected 2.5 fb-1 at the peak of the ? resonance, and 250 pb-1 at ? {s}=1 GeV. The latest experimental results based on a sample of 450 pb-1 are presented in this paper: they mainly concern the neutral and charged kaon decays, and the radiative ? decays into scalar and pseudoscalar mesons.

  15. Domain annotation of trimeric autotransporter adhesins—daTAA

    PubMed Central

    Szczesny, Pawel; Lupas, Andrei

    2008-01-01

    Motivation: Trimeric autotransporter adhesins (TAAs), such as Yersinia YadA, Neisseria NadA, Moraxella UspAs, Haemophilus Hia and Bartonella BadA, are important pathogenicity factors of proteobacteria. Their high sequence diversity and distinct mosaic-like structure lead to difficulties in the annotation of their sequences. These stem from the large number of short repeats, the presence of compositionally unusual coiled-coils, fuzzy domain boundaries and regions of seemingly low sequence complexity. Results: We have developed a workflow, named daTAA, for the accurate domain annotation of TAAs. Its core consists of manually curated alignments and of knowledge-based rules that enhance assignments made by sequence similarity. Compared to general domain annotation servers such as PFAM, daTAA captures more domains and provides more sensitive domain detection, as well as integrated and detailed coiled-coil assignments. Availability: The daTAA server is freely accessible at http://toolkit.tuebingen.mpg.de/dataa Contact: andrei.lupas@tuebingen.mpg.de Supplementary information: Supplementary data are available at Bioinformatics online. PMID:18397894

  16. Identification of an abundant 56 kDa protein implicated in food allergy as granule-bound starch synthase

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Rice, the staple food of South and East Asian counties, is considered to be hypoallergenic. However, several clinical studies have documented rice-induced allergy in sensitive patients. Rice proteins with molecular weights of 14-16 kDa, 26 kDa, 33 kDa and 56 kDa have been identified as allergens. Re...

  17. A influência da respiração oral na oclusão dentária: uma visão geral da literatura The influence of oral breathing on dental occlusion: a literature overview

    Microsoft Academic Search

    Edna Namiko Izuka

    2008-01-01

    ResumO Introdução: A respiração oral é uma condição extremamente freqüente, particularmente na população pediátrica, e acredi- ta-se que ao longo do tempo, ela possa influenciar o padrão de desenvolvimento das estruturas craniofaciais, levando às alterações importantes da oclusão dentária. Objetivo: Veri- ficar os aspectos diagnósticos e preventivos da má oclusão dentária secundária à respiração oral na literatura científica. Método: Revisão

  18. Fortaleza’s Feminisms: Searching for Feminist Theory in the Centro de Referência da Mulher and the Delegacia de Defesa da Mulher

    Microsoft Academic Search

    Paige Sweet

    2008-01-01

    This study attempts to focus on the issue of how violence against women is combated in Brazil through interviewing the women who work at the Delegacia de Defesa da Mulher and the Centro de Referência da Mulher. I attempt to compare and contrast the policies and procedures of these two institutions, as well as the opinions of the women who

  19. Tutorial de Pesquisa Bibliogrfica Este Tutorial faz parte da programao de treinamentos

    E-print Network

    Paraná, Universidade Federal do

    internacional da área médica e biomédica, produzida pela NLM (National Library of Medicine, USA) e que contêm. Disponibilizada desde 1966 #12;8 MEDLINE via PubMed - www.pubmed.org Base da NLM (National Library of Medicine PubMed e principal base de dados da National Library of Medicine (NLM). Contêm mais de 17 milhões de

  20. A novel 45 kDa secretory protein from rat olfactory epithelium: primary structure and localisation

    Microsoft Academic Search

    Maria I. Merkulova; Svetlana G. Andreeva; Tatyana M. Shuvaeva; Sergey V. Novoselov; Igor V. Peshenko; Marina F. Bystrova; Vladimir I. Novoselov; Evgeny E. Fesenko; Valery M. Lipkin

    1999-01-01

    cDNA clones encoding the 45 kDa protein were isolated from a rat olfactory epithelium cDNA library and their inserts were sequenced. The reconstructed protein sequence comprises 400 amino acids with a calculated molecular mass of 46?026 Da. A homology was revealed between the amino acid sequence of the 45 kDa protein and the proteins involved in the transfer of hydrophobic

  1. Easy CD-DA Extractor 4.5.2

    NSDL National Science Digital Library

    2001-01-01

    Billing itself as "the most complete CD-ripping solution available" as well as the fastest (a 40 percent increase in performance since the last edition), Easy CD-DA Extractor supports a variety of formats: mp3, Windows Media Player, Ogg Vorbis, TwinVQ, .wav, and .aiff. Using the program, you can copy CDs and convert from any of the supported formats (except .aiff) to any other. Users can define the length of the tracks they record; download in formation from the freedb, the Internet Compact Disc Database; normalize the music; and more. The program is shareware and costs $19.95.

  2. Fundao Universidade de Braslia 4 RELATRIO DE ATIVIDADES DA COMISSO

    E-print Network

    Lucero, Jorge Carlos

    /09/2011) Comissão Permanente do REUNI: Márcia Abrahão Moura, Presidente Denise Imbroisi, Secretária Executiva do Nascimento José Américo Soares Garcia Márcia Abrahão Moura Maria Ivoneide de Lima Brito Marcos Vinícius da de presenças/nº de reuniões Márcia Abrahão Moura Decana de Graduação - Presidente 07/07 Denise

  3. Visual tracking of da Vinci instruments for laparoscopic surgery

    NASA Astrophysics Data System (ADS)

    Speidel, S.; Kuhn, E.; Bodenstedt, S.; Röhl, S.; Kenngott, H.; Müller-Stich, B.; Dillmann, R.

    2014-03-01

    Intraoperative tracking of laparoscopic instruments is a prerequisite to realize further assistance functions. Since endoscopic images are always available, this sensor input can be used to localize the instruments without special devices or robot kinematics. In this paper, we present an image-based markerless 3D tracking of different da Vinci instruments in near real-time without an explicit model. The method is based on different visual cues to segment the instrument tip, calculates a tip point and uses a multiple object particle filter for tracking. The accuracy and robustness is evaluated with in vivo data.

  4. Recent Results from Kloe at DA?NE

    NASA Astrophysics Data System (ADS)

    Martini, M.; Ambrosino, F.; Antonelli, A.; Antonelli, M.; Archilli, F.; Bacci, C.; Beltrame, P.; Bencivenni, G.; Bertolucci, S.; Bini, C.; Bloise, C.; Bocchetta, S.; Bossi, F.; Branchini, P.; Campana, P.; Capon, G.; Capussela, T.; Ceradini, F.; Cesario, F.; Chi, S.; Chiefari, G.; Ciambrone, P.; Crucianelli, F.; De Lucia, E.; de Santis, A.; de Simone, P.; de Zorzi, G.; Denig, A.; di Domenico, A.; di Donato, C.; di Micco, B.; Doria, A.; Dreucci, M.; Felici, G.; Ferrari, A.; Ferrer, M. L.; Fiore, S.; Forti, C.; Franzini, P.; Gatti, C.; Gauzzi, P.; Giovannella, S.; Gorini, E.; Graziani, E.; Kluge, W.; Kulikov, V.; Lacava, F.; Lanfranchi, G.; Lee-Franzini, J.; Leone, D.; Martini, M.; Massarotti, P.; Mei, W.; Meola, S.; Miscetti, S.; Moulson, M.; Müller, S.; Murtas, F.; Napolitano, M.; Nguyen, F.; Palutan, M.; Pasqualucci, E.; Passeri, A.; Patera, V.; Perfetto, F.; Primavera, M.; Santangelo, P.; Saracino, G.; Sciascia, B.; Sciubba, A.; Sibidanov, A.; Spadaro, T.; Testa, M.; Tortora, L.; Valente, P.; Venanzoni, G.; Versaci, R.; Xu, G.

    We report in the following, latest results from the KLOE detector at DA?NE, the Frascati ?-factory. KLOE has collected 2.5 fb-1 of e+e- collisions at center of mass energy around the ? mass. We are completing the analyses of the 2001-2002 data sample of 450 pb-1 and we present selected results based on the complete data sample. KLOE results could be divided into two categories kaonic and hadronic physics. We present last results on both topics describing the impact of the KLOE physics.

  5. Recombinant 43-kDa USF binds to DNA and activates transcription in a manner indistinguishable from that of natural 43/44-kDa USF.

    PubMed Central

    Pognonec, P; Roeder, R G

    1991-01-01

    USF is a cellular factor involved in the transcriptional regulation of several cellular and viral promoters. Purified USF from HeLa cells (HeLa USF) consists of 43- and 44-kDa polypeptides which show independent binding to a specific DNA element. A cDNA encoding the 43-kDa species has been previously cloned. We show here that the purified form of bacterially expressed 43-kDa USF (i) exists in solution as a dimer whose formation is greatly favored under reducing conditions, (ii) binds to its cognate DNA sequence in a manner indistinguishable from that of HeLa USF, and (iii) is as efficient as HeLa USF in stimulating transcription from target promoters in a reconstituted cell-free system. Additional data indicate that the 44-kDa component of HeLa USF is immunologically unrelated to the 43-kDa polypeptide but is associated with it in HeLa cell extracts. These results suggest that the 43-kDa component possesses an intrinsic DNA binding and transcriptional activation potential and that the 44-kDa USF component of the natural USF complex may have some regulatory role. Images PMID:1922036

  6. [Textual Research on Chiding Disease and Matixiang Herb in Da he wai ke (External Medicine of Da He)].

    PubMed

    Pu, Xiao-Lan; Zhang, Yi; Yang, Wen-Yu; Wu, Ya-Mei

    2012-11-01

    Recorded in Da he wai ke (The External Medicine of Da He) in the Ming dynasty without a corresponding disease title in contemporary scholarly concepts of Traditional Chinese Medicine (TCM), Chiding disease was described as an acute symptomatic disease with inevitable serious conditions of convulsion-like or mania-like behavior, and as a refractory ailment. It was also considered as an alias of Hongsiding (namely the acute lymphangitis) in few ancient books. Matixiang, a Chinese herb for treatment of Chiding, was regarded as a nonsuch drug by Da he wai ke, and was considered as a take-then-cure drug by Chuang yang jing yan quan shu (Compendium for Experience in Sores Diseases). The present studies about Chiding and Matixiang show that: (1) the name of Chiding was first seen in Zhong zang jing (Master Hua's Classic of the Viscera) ; (2) Chiding was rarely mentioned in medical literature of the Song, Yuan and Qing Dynasty, but mostly seen in the Ming Dynasty; (3) Xinding and Huoyanding were found as synonyms of Chiding ; (4) the distinction between Chiding and Hongsiding (flaming sore) was revealed by comparison analysis of their etiology, affected part(s), symptoms, prognosis and syndromic pictures; (5) Chiding on the tongue is the same as "Tongue Ding" or "Sublingual Ding" in contemporary TCM and as "Sublingual Space Infection" in Western Medicine. Moreover, Chiding on the hands, feet or other skin parts could be classified as "Hands/Feet Ding" in contemporary TCM and as "Furuncle" (i.e., Acute Suppurative Folliculitis and Perifolliculitis or cellulites of the tongue) in Western Medicine; (6) Matixiang is probably deduced as Asarum forbesii Maxim., A. ichangense C. Y. Cheng et C. S. Yang, family Aristolochiaceae, or Valeriana jatamansi Jones., family Valerianaceae. PMID:23363849

  7. Cyclosporine A affects open field behavior in DA rats.

    PubMed

    von Hörsten, S; Exton, M S; Vöge, J; Schult, M; Nagel, E; Schmidt, R E; Westermann, J; Schedlowski, M

    1998-05-01

    Since the introduction of Cyclosporine A (CsA) for immunosuppression in solid-organ transplantation, the rate of allograft rejection has decreased substantially. However, treatment with CsA induces neuropsychological complications in patients, including affective disorders such as anxiety, disorientation, depression, aggression, paranoia, and apathy. These CsA-induced affective side effects cannot be extensively studied in humans. Therefore, this study investigates the effects of intraperitoneal CsA (20 mg/kg) injections on the open-field behavior of male Dark Agouti (DA) rats 1, 6, 12, and 23 h after drug administration on 3 consecutive days. CsA induced an increase in emotionality in DA rats 6 h after injection, reflected by decreased ambulatory activity in the open field and increased defecation. In addition, a decrease in rearing activity was observed 12 h after CsA administration. These behavioral alterations are discussed in the view of changes in cytokine profiles induced by CsA. PMID:9610926

  8. Divulgamos a lista de associados pais/mes/responsveis, em virtude do processo eleitoral para escolha da nova diretoria da APP que ser aberto em breve. Qualquer

    E-print Network

    Floeter, Sergio Ricardo

    . ANDRÉA MICHEL DE LIMA 37. ANDREA PERELMUTR GONÇALVES 38. ANDRESSA DA COSTA FARIAS 39. ANDREZA VALDA DIAS. CLAUDIA LEAL DE SOUZA MARTINS 73. CLAUDIA VITORIA HASCKEL LOCH 74. CLAUDINE MARIA FLORES LAGO 75. CLAUDIO

  9. Mtodo de Fibonacci Como no mtodo da "Golden Section" o procedimento de procura de Fibonacci faz

    E-print Network

    Instituto de Sistemas e Robotica

    Método de Fibonacci Como no método da "Golden Section" o procedimento de procura de Fibonacci faz incerteza varia duma iteração para outra. O procedimento é baseado na sequência de Fibonacci Fn{ } definida acontece com os métodos da procura dicotómica e de "Golden section", o método de Fibonacci requer que o

  10. Universidade Federal de Santa Catarina-Campus Joinville Centro de Engenharia da Mobilidade

    E-print Network

    Floeter, Sergio Ricardo

    .petemb.ufsc.br BoletimInformativo Editorial Com o objetivo de potencializar a aprendizagem e o aperfeiçoamento contínuo Informativo do Programa de Educação Tutorial do CEM. O PET é um programa que busca a integração discente Tutorial Engenharia da Mobilidade www.petemb.ufsc.br Aconteceu no CEM 1ª Feira da Mobilidade Texto

  11. Revista da Biologia www.ib.usp.br/revista ISSN 1984-5154 Sumrio _____________________________ Volume 2

    E-print Network

    Morandini, Andre C.

    _____________________________ Volume 2 Junho de 2009 Ensaio: 1 A ciência vale a pena? Arnaldo Cheixas-Dias 8 Uma visão holística sobre os ecossistemas fluviais Aline Sueli de Lima Rodrigues Revisão: 12 Fisiologia da música: uma abordagem comparativa Felipe Viegas Rodrigues Artigo: 18 As características da cobertura vegetal do distrito

  12. Characterisation of the 5 kDa growth hormone isoform GERARD SUCH-SANMARTIN1

    E-print Network

    Pompeu Fabra, Universitat

    Characterisation of the 5 kDa growth hormone isoform GERARD SUCH-SANMARTI´N1 , JAUME BOSCH1 , JORDI-terminal fragment of 43 amino acids of human growth hormone (GH) shows a specific and significant in-vivo insulin as a potential agent for obesity-related diseases is discussed. Keywords: Growth hormone, 5 kDa, GH1­43, solid

  13. DIRECTORY OF ESReDA ACCIDENT DATABASES Jean-Philippe PINEA

    E-print Network

    Paris-Sud XI, Université de

    98-62 DIRECTORY OF ESReDA ACCIDENT DATABASES Jean-Philippe PINEAÜ INERIS - Parc Technologique Alata of the ESReDA directory (issued in 1997) of accident databases involving chemicals. First, the requirements ofthe existing directory is given. The review will end on the current work on a guidance document

  14. Projeto CityOn da Biodroid entre os finalistas dos Digital Communication

    E-print Network

    Instituto de Sistemas e Robotica

    Especiais Críticas Antevisões Vídeos Imagens Downloads Truques e Dicas 3DS DS PC PS3 PSP VITA WII WIIU X360-se entre os finalistas na categoria Best Corporate Games. O projeto CityOn da Biodroid, EDP e Instituto finalistas na categoria Best Corporate Games, o jogo da Biodroid coloca o jogador no papel de gestor dos

  15. Zooarqueologia dos mamferos aquticos e semi-aquticos da Ilha de Santa Catarina, sul do Brasil

    E-print Network

    Simões-Lopes, Paulo César

    Zooarqueologia dos mamíferos aquáticos e semi-aquáticos da Ilha de Santa Catarina, sul do Brasil aquáticos e semi-aquáticos da Ilha de Santa Catarina, sul do Brasil. This study analyzes the use of aquatic humana pré-histórica são abundantes na região sul do Brasil, inclusive na Ilha de Santa Catarina, devido

  16. OUTRAMENTE QUE SER: REVOLVENDO QUESTÕES À LUZ DA PEDAGOGIA DO OPRIMIDO

    Microsoft Academic Search

    Aida Maria Lovison; Guilherme Dornelas Camara

    2008-01-01

    p. 7-17 RESUMO - Neste texto, a ética da alte- ridade de Emmanuel Levinas, para quem a nudez do rosto não é uma figura de estilo, mas a consciência moral, encontra a teoria da ação (cultural) dialógica, fundamento, na pedagogia do oprimido de Paulo Freire, de sua denúncia-anúncio contra a desu- manização e a opressão. Para ambos, a violência toma

  17. 32 CFR 516.14 - Service of process on DA or Secretary of Army.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...Service of process on DA or Secretary of Army. 516.14 Section 516.14 National...Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS...Service of process on DA or Secretary of Army. The Chief, Litigation...

  18. 32 CFR 516.14 - Service of process on DA or Secretary of Army.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...Service of process on DA or Secretary of Army. 516.14 Section 516.14 National...Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS...Service of process on DA or Secretary of Army. The Chief, Litigation...

  19. 32 CFR 516.14 - Service of process on DA or Secretary of Army.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...Service of process on DA or Secretary of Army. 516.14 Section 516.14 National...Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS...Service of process on DA or Secretary of Army. The Chief, Litigation...

  20. Asteroid 2012 DA14 To Whiz Past Earth Safely - Duration: 5 minutes, 1 second.

    NASA Video Gallery

    The small near-Earth asteroid 2012 DA14 will pass very close to Earth on Feb. 15, 2013. Asteroid 2012 DA14 will be closest to Earth at about 11:24 a.m. PST (2:24 p.m. EST and 1924 UTC), on Feb. 15,...

  1. Facultade de Ciencias da Educacin Mster Universitario en Didcticas Especficas por la Universidad de A Corua

    E-print Network

    Fraguela, Basilio B.

    Facultade de Ciencias da Educación Máster Universitario en Didácticas Específicas por la A CORUÑA Memoria de Verificación Facultad de Ciencias de la Educación Universidad de A Coruña Año 2013 #12;Facultade de Ciencias da Educación Máster Universitario en Didácticas Específicas por la Universidad de

  2. Facultade de Ciencias da Educacin Mster Universitario en Direccin, Gestin e Innovacin de Instituciones Escolares y

    E-print Network

    Fraguela, Basilio B.

    Facultade de Ciencias da Educación Máster Universitario en Dirección, Gestión e Innovación de Memoria de Verificación Facultad de Ciencias de la Educación Universidad de A Coruña Año 2013 #12;Facultade de Ciencias da Educación Máster Universitario en Dirección, Gestión e Innovación de Instituciones

  3. 244 201 3 /2014 C A L E N DA R Mohsin Khalil

    E-print Network

    Sokolowski, Marla

    Communication for International Professionals 250 Canadian Workplace Culture and Communication (CWCC) 250244 201 3 /2014 C A L E N DA R Mohsin Khalil Student, Certificate in Business Innovation "The 201 3 /2014 C A L E N DA R Contents 248 U of T Mississauga 248 Business & Professional Studies 248

  4. References: [1] Butts DA, Weng C, Jin JZ, Yeh CI, Lesica NA, Alonso JM, Stanley GB

    E-print Network

    Butts, Daniel

    References: [1] Butts DA, Weng C, Jin JZ, Yeh CI, Lesica NA, Alonso JM, Stanley GB (2007) Temporal precision in the neural code and the time scales of natural vision. Nature 449: 92-5. [2] Butts DA, Weng C in the retina and LGN Daniel A. Butts1 , Alexander R. R. Casti2 1) Dept. of Biology and Program in Neuroscience

  5. The Indicative and Subjunctive "da"-complements in Serbian A Syntactic-Semantic Approach

    ERIC Educational Resources Information Center

    Todorovic, Natasa

    2012-01-01

    A syntactic-semantic investigation of subjunctive and indicative "da"-complements in Serbian is conducted in this project. After a careful comparison of Serbian sentence constructions with "da"-complements to the equivalent sentence structures in languages of the Balkans as well as other Slavic languages, it is clearly…

  6. A CONSERVAÇÃO DA BIODIVERSIDADE E SUA RELAÇAO COM A EDUCAÇÃO AMBIENTAL

    Microsoft Academic Search

    Lúcia Gracia Ferreira; Adriana Guerra Ferreira; Izabela Antunes Oliveira; Maria das Graças; Porto Pires

    2008-01-01

    Resumo : Este trabalho bibliográfico objetivou fazer a relação entre conservação da biodiversidade e a educação ambiental, buscando alternativas de mudar essa realidade. Assim, nos atemos em conhecer algumas características da biodiversidade brasileira e os problemas enfrentados para sua conservação. A partir de então propomos um caminho: a educação ambiental. Palavras-chave : conservação, educação, biodiversidade. Abstract : This bibliographical work

  7. Effect of DA-9701 on Colorectal Distension-Induced Visceral Hypersensitivity in a Rat Model

    PubMed Central

    Kim, Eun Ran; Min, Byung-Hoon; Lee, Tae Ho; Son, Miwon; Rhee, Poong-Lyul

    2014-01-01

    Background/Aims DA-9701 is a newly developed drug made from the vegetal extracts of Pharbitidis semen and Co-rydalis tuber. The aim of this study was to evaluate the effect of DA-9701 on colorectal distension (CRD)-induced visceral hypersensitivity in a rat model. Methods Male Sprague-Dawley rats were subjected to neonatal colon irritation (CI) using CRD at 1 week after birth (CI group). At 6 weeks after birth, CRD was applied to these rats with a pressure of 20 to 90 mm Hg, and changes in the mean arterial pressure (MAP) were measured at baseline (i.e., without any drug administration) and after the administration of different doses of DA-9701. Results In the absence of DA-9701, the MAP changes after CRD were significantly higher in the CI group than in the control group at all applied pressures. In the control group, MAP changes after CRD were not significantly affected by the administration of DA-9701. In the CI group, however, the administration of DA-9701 resulted in a significant decrease in MAP changes after CRD. The administration of DA-9701 at a dose of 1.0 mg/kg produced a more significant decrease in MAP changes than the 0.3 mg/kg dose. Conclusions The administration of DA-9701 resulted in a significant increase in pain threshold in rats with CRD-induced visceral hypersensitivity. PMID:25071903

  8. 76 FR 55293 - Special Conditions: Diamond Aircraft Industries, Model DA-40NG; Electronic Engine Control (EEC...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-07

    ...23-10-03-SC] Special Conditions: Diamond Aircraft Industries, Model DA-40NG...notice proposes special conditions for the Diamond Aircraft Industries (DAI), model DA-40NG...commenter. Background On May 11, 2010 Diamond Aircraft Industry GmbH applied for...

  9. 76 FR 72087 - Special Conditions: Diamond Aircraft Industries, Model DA-40NG; Electronic Engine Control (EEC...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-22

    ...23-253-SC] Special Conditions: Diamond Aircraft Industries, Model DA-40NG...special conditions are issued for the Diamond Aircraft Industries, Model DA-40NG...INFORMATION: Background On May 11, 2010, Diamond Aircraft Industry GmbH applied for...

  10. Os direitos da mulher à terra e os movimentos sociais rurais na reforma agrária brasileira

    Microsoft Academic Search

    Carmen Diana Deere

    2004-01-01

    R R R R Resumo: esumo: esumo: esumo: esumo: Este artigo examina a evolução da reivindicação dos direitos da mulher à terra na reforma agrária brasileira sob o prisma dos três principais movimentos sociais rurais: o Movimento dos Trabalhadores Rurais Sem Terra (MST), os sindicatos rurais e o movimento autônomo de mulheres rurais. O mérito maior por levantar a questão

  11. A Value-Engaged Approach for Evaluating the Bunche-Da Vinci Learning Academy

    ERIC Educational Resources Information Center

    Greene, Jennifer C.

    2005-01-01

    In 2001, the Bunche Academy was chosen by its district to join in partnership with the Da Vinci Learning Corporation to embark on an ambitious whole-school reform initiative, especially designed by the corporation for low-performing schools. In this chapter, the author describes how, as illustrated in the Bunche-Da Vinci Learning Academy context,…

  12. A Proposal to Build Evaluation Capacity at the Bunche-Da Vinci Learning Partnership Academy

    ERIC Educational Resources Information Center

    King, Jean A.

    2005-01-01

    The author describes potential evaluation capacity-building activities in contrast to the specifics of an evaluation design. Her response to the case of the Bunche-Da Vinci Learning Partnership Academy is developed in three parts: (1) an initial framing of the Bunche-Da Vinci situation; (2) what should be done before signing a contract; and (3)…

  13. A Creative Approach to the Common Core Standards: The Da Vinci Curriculum

    ERIC Educational Resources Information Center

    Chaucer, Harry

    2012-01-01

    "A Creative Approach to the Common Core Standards: The Da Vinci Curriculum" challenges educators to design programs that boldly embrace the Common Core State Standards by imaginatively drawing from the genius of great men and women such as Leonardo da Vinci. A central figure in the High Renaissance, Leonardo made extraordinary contributions as a…

  14. ANÁLISE DA EFICIÊNCIA ECONÔMICA DOS PRODUTORES DE LEITE NO ESTADO DE MINAS GERAIS

    Microsoft Academic Search

    Andre Luis Ribeiro Lima; Ricardo Pereira Reis; Luiz Eduardo Gaio; Fabricio Teixeira Andrade; Claudia Salgado Gomes

    2008-01-01

    O aumento da eficiência produtiva e econômica é fator decisivo para a competitividade do setor leiteiro que, produzindo com menor custo, beneficiará toda a cadeia do leite. Dessa maneira, a unidade de produção pode ter, na eficiência produtiva, a condição necessária para a sobrevivência e o crescimento dentro da economia de mercado. Considerado o maior produtor de leite do Brasil,

  15. Avaliação de resíduos da fabricação de enzimas nas características químicas de um Cambissolo

    Microsoft Academic Search

    Francisco Ribeiro; Rua Francisco Ribeiro; Ulisses José Ribeiro

    Resumo - Os resíduos industriais e biossólidos reaproveitados na agricultura possuem potencial par a melhorar as características químicas e físicas do s olo, e evitando perda via reciclagem destes resíduos. Co m o objetivo de avaliar a utilização de substrato da fermentação microbiana inativado com Ca(OH) 2, oriundo da fabricação de enzimas industriais (proteases), sobre as características químicas do s

  16. TRAJETÓRIA DE CONVERSÃO AGROECOLÓGICA DE AGRICULTORES FAMILIARES DO SUDESTE DA AMAZÔNIA

    Microsoft Academic Search

    Lucimar Santiago Abreu; Amauri Siviero; Stephane Bellon

    2008-01-01

    O sistema de uso da terra baseado na implantação de sistemas agro florestais na Amazônia é fortemente recomendado pela pesquisa agropecuária brasileira, no entanto, poderia apresentar algumas restrições no âmbito da sustentabilidade econômica de modo a colocar em risco eminente a população menos favorecida deste território. Para equacionar tal problemática de pesquisa analisamos o processo de emergência e de desenvolvimento

  17. Mtodo e loucura da teorizao em psicanlise: a busca de figurabilidade

    E-print Network

    1 Método e loucura da teorização em psicanálise: a busca de figurabilidade Theorising Method búsqueda de la figurabilidad Thamy Ayouch1 (Ayouch T. (2013) :"Método e loucura da teorização em vincular a teorização, a ficção e a prática analítica. Palavras-chave: Teorização, afetividade, loucura

  18. O METRO E A CIDADE. Das representaes da causalidade integrao transporte/ordenamento em Paris.

    E-print Network

    Paris-Sud XI, Université de

    1 O METRO E A CIDADE. Das representações da causalidade à integração transporte/ordenamento em Paris. _____________________ Palavras-chave : metro ­ causalidade ­ avaliação ­ efeitos ­ infra entre a expansão do metro parisiense nos arredores da capital francesa e o tecido urbano e social do

  19. Perfil dos pacientes com hanseníase em área hiperendêmica da Amazônia do Maranhão, Brasil

    Microsoft Academic Search

    Antônio Augusto; Jackson Maurício

    Resumo Estudo transversal, realizado de agosto\\/1998 a novembro\\/2000, envolvendo 207 pacientes hansenianos com o objetivo de analisar o perfil socioeconômico, demográfico e ambiental e as incapacidades físicas em decorrência da doença. O estudo foi desenvolvido em Buriticupu, área hiperendêmica em hanseníase, localizado na Amazônia do Maranhão. O grau de incapacidade foi determinado de acordo com o Ministério da Saúde do

  20. DA-9701: A New Multi-Acting Drug for the Treatment of Functional Dyspepsia

    PubMed Central

    Kwon, Yong Sam; Son, Miwon

    2013-01-01

    Motilitone® (DA-9701) is a new herbal drug that was launched for the treatment of functional dyspepsia in December 2011 in Korea. The heterogeneous symptom pattern and multiple causes of functional dyspepsia have resulted in multiple drug target strategies for its treatment. DA-9701, a compound consisting of a combination of Corydalis Tuber and Pharbitidis Semen, has being developed for treatment of functional dyspepsia. It has multiple mechanisms of action such as fundus relaxation, visceral analgesia, and prokinetic effects. Furthermore, it was found to significantly enhance meal-induced gastric accommodation and increase gastric compliance in dogs. DA-9701 also showed an analgesic effect in rats with colorectal distension induced visceral hypersensitivity and an antinociceptive effect in beagle dogs with gastric distension-induced nociception. The pharmacological effects of DA-9701 also include conventional effects, such as enhanced gastric emptying and gastrointestinal transit. The safety profi le of DA-9701 is also preferable to that of other treatments. PMID:24265862

  1. Evidence for a 12?kDa “Carrier Protein” for Natriuretic Hormone

    PubMed Central

    Gonick, Harvey C.

    2014-01-01

    The search for the elusive Na-K-ATPase-inhibiting natriuretic hormone continues. In this review, evidence is presented that isolating the carrier protein for natriuretic hormone from hypertensive plasma is a necessary first step before splitting off the final hormone. The carrier protein has a molecular weight of 12?kDa while the final hormone has a molecular weight of 408?Da. Both compounds inhibit Na-K-ATPase but the compound containing the carrier protein predominates. The question has been raised as to whether the carrier protein is in actuality proANF, a 17?kDa protein that can be split between a 14?kDa protein (the presumptive proANF) and the 3?kDa ANF. PMID:25477863

  2. Uma Introduo Engenharia de Ontologias no contexto da Web Anarosa Alves Franco Brando, Carlos Jos Pereira de Lucena

    E-print Network

    Endler, Markus

    proposta por Tim Berners-Lee, o criador da www, ainda no seu documento seminal [8]. Neste documento ele) mostrou um caminho a ser seguido a fim de tornar possível a materialização da proposta de Berners-Lee de

  3. 40 CFR 60.45Da - Alternative standards for combined nitrogen oxides (NOX) and carbon monoxide (CO).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 false Alternative standards for combined nitrogen oxides (NOX) and carbon monoxide (CO). 60.45Da Section...Generating Units § 60.45Da Alternative standards for combined nitrogen oxides (NOX ) and carbon monoxide (CO). (a)...

  4. 40 CFR 60.45Da - Alternative standards for combined nitrogen oxides (NOX) and carbon monoxide (CO).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 false Alternative standards for combined nitrogen oxides (NOX) and carbon monoxide (CO). 60.45Da Section...Generating Units § 60.45Da Alternative standards for combined nitrogen oxides (NOX ) and carbon monoxide (CO). (a)...

  5. 40 CFR 60.45Da - Alternative standards for combined nitrogen oxides (NOX) and carbon monoxide (CO).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 false Alternative standards for combined nitrogen oxides (NOX) and carbon monoxide (CO). 60.45Da Section...Generating Units § 60.45Da Alternative standards for combined nitrogen oxides (NOX ) and carbon monoxide (CO). (a)...

  6. [Initial experience with da Vinci robotic system in vascular surgery].

    PubMed

    Stádler, P; Vitásek, P; Matous, P

    2006-05-01

    Robotic operational systems improve accuracy, control of and skilful management of surgical procedures up to levels unachievable by a human factor itself. A surgeon is also allowed to conduct the types of miniinvasive procedures, which cannot be conducted using contemporary technologies. High degree of the procedure's safety can be achieved. Currently, the robotic surgical systems are used in top clinics worldwide and the concept of the robotic operating theatre is considered to become standard for some procedures in future. In October 2005, a multispecialist robotic centre was opened in the Hospital Na Homolce, which then created a new qualitative standard in the miniinvasive surgical management. The authors present the initial group of patients, who were operated from November 2005 to January 2006 with employement of the da Vinci robotic system, listing its pros and cons. PMID:16805339

  7. 70 DA WHITE DWARFS IDENTIFIED IN LAMOST PILOT SURVEY

    SciTech Connect

    Zhao, J. K.; Luo, A. L.; Zhao, G. [Key Laboratory of Optical Astronomy, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 (China); Oswalt, T. D., E-mail: zjk@bao.ac.cn, E-mail: gzhao@bao.ac.cn, E-mail: lal@bao.ac.cn, E-mail: toswalt@fit.edu [Physics and Space Science Department, Florida Institute of Technology, Melbourne, FL 32901 (United States)

    2013-06-01

    We present a spectroscopically identified catalog of 70 DA white dwarfs (WDs) from the LAMOST pilot survey. Thirty-five are found to be new identifications after cross-correlation with the Eisenstein et al. and Villanova catalogs. The effective temperature and gravity of these WDs are estimated by Balmer lines fitting. Most of them are hot WDs. The cooling times and masses of these WDs are estimated by interpolation in theoretical evolution tracks. The peak of the mass distribution is found to be {approx}0.6 M {sub Sun }, which is consistent with prior work in the literature. The distances of these WDs are estimated using the method of synthetic spectral distances. All of these WDs are found to be in the Galactic disk from our analysis of space motions. Our sample supports the expectation that WDs with high mass are concentrated near the plane of the Galactic disk.

  8. DBS -- An rlogin multiplexer and output logger for DA systems

    SciTech Connect

    Oleynik, G.; Appleton, L.; Udumula, L.; Votava, M.

    1994-04-01

    DART Bootstrap Services (dbs) is the first component of run-control for the DART Data Acquisition system -- the DA for the 96` round of experiments at Fermilab -- though it has potential usefulness as a powerful tool in other distributed applications. dbs is an rlogin session multiplexer. It allows a user, running a single program, to start up any number of remote login sessions, feed shell commands to them, and collect their output into a single (or multiple) log files (a server keeps the sessions open and collects their output). From this program, any session can be attached to interactively so it appears just like an rlogin session -- dbs becomes transparent. When finished with this interactive mode, the user can escape back to dbs and attach to a different session if so desired. Among many other useful features, dbs supplies a mechanism for cleanup (deletion) of all processes created under a session, allowing a fresh start.

  9. Pharmacological action of DA-9701 on the motility of feline stomach circular smooth muscle.

    PubMed

    Nguyen, Thanh Thao; Song, Hyun Ju; Ko, Sung Kwon; Sohn, Uy Dong

    2015-03-01

    DA-9701, a new prokinetic agent for the treatment of functional dyspepsia, is formulated with Pharbitis semen and Corydalis tuber. This study wasconducted to determine the pharmacological action of DA-9701 and to identify the receptors involved in DA-9701 -induced contractile responsesin the feline gastric corporal, fundic and antral circular smooth muscle. Concentration-response curve to DA-9701 was established. The tissue trips were exposed to methylsergide, ketanserin, ondansetron, GR 113808, atropine and dopamine before administration of DA-9701. The contractile force was determined before and after administration of drugs by a polygraph.DA-9701 enhanced the spontaneous contractile amplitude of antrum, corpus and fundus. However, it did not change the spontaneous contractile frequency of antrum and corpus, but concentration-dependently reduced that of fundus. In the fundus, DA-9701 -induced tonic contractions were inhibited by dopamine, methylsergide, ketanserine, ondansetron or GR 113808 respectively, but not by atropine, indicating that the contractile responses are mediated by multiple receptors: 5-HT2, 5-HT3, 5-HT4, and dopamine receptors. In the corpus, DA-9701-induced contractions were blocked by atropine, dopamine or GR 113808, but not by methysergide, ketanserin or ondansetron, indicating that they are involved in receptors on both, smooth muscles and neurons: 5-HT4 and dopamine receptors. However, contractile responses to DA-9701 are mainly mediated by dopamine receptors in the antrum. These results suggest that DA-9701 has important roles in gastric accommodation by enhancing tonic activity of fundus, and in gastric emptying and gastrointestinal transit by phasic contractions of corpus and antrum mediated by multiple receptors. PMID:25980179

  10. DaVinci-assisted laparoscopic radical prostatectomy: the learning curve

    NASA Astrophysics Data System (ADS)

    Le, Carter Q.; Ho, Khai-Linh V.; Gettman, Matthew T.

    2007-02-01

    Objective: To define the learning curve for daVinci-assisted laparoscopic radical prostatectomy (DLP) at our institution. Methods: The data from 170 patients who underwent DLP between August 2002 and December 2004 by a single surgeon (MTG) were reviewed. Operative time, hemoglobin decrease, conversion to open procedure, positive margin rates, complications, length of stay (LOS), length of catheterization, continence, and erectile function were analyzed. Results: Hemoglobin decrease (p=0.11), positive margin rates (p=0.80), and early urinary continence (p=0.17) did not significantly correlate with surgical experience. A trend towards lower complications (p=0.07) and an earlier return of erectile function (p=0.09) was noted with increased experience with DLP. Operative time, hospital stay, catheterization time, and open conversion showed significant association with patient sequence. Median operative time for the first 60 and the last 110 patients was 323.5 and 239.5 minutes (p=<0.0001), respectively. Median LOS for the aforementioned groups was 53 and 51 hours (p=0.009). Length of catheterization declined significantly between the first 60 and the remaining 110 patients, 14 as compared to 11.5 days (p=<0.0001). Eight open conversions occurred, six were in the first 30 patients (p=0.03). Conclusion: As an indicator of the learning curve, the operative time in our series showed no correlation with sequence after the 60 th patient. Thus, despite the advantages of robotics, the learning curve to efficient performance of daVinciassisted laparoscopic radical prostatectomy is long. Oncological and functional outcomes should not be affected during the learning curve.

  11. Analise do Impacto da Rede Social na Marcac~ao de Fotos como Favoritas no Flickr1

    E-print Network

    Cirne, Walfredo

    An´alise do Impacto da Rede Social na Marcac¸~ao de Fotos como Favoritas no Flickr1 Luiz Alves favoritos. Neste trabalho analisamos o impacto da rede de contatos na avaliac¸~ao de fotos utilizando dados da rede social Flickr1 , um dos mais importantes sites de compartilhamento de fotos, que possui milh

  12. 11 CFR 111.11 - Written questions under order (2 U.S.C. 437d(a)(1)).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...Written questions under order (2 U.S.C. 437d(a)(1)). 111.11 Section...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...Written questions under order (2 U.S.C. 437d(a)(1)). The...

  13. 11 CFR 111.11 - Written questions under order (2 U.S.C. 437d(a)(1)).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...Written questions under order (2 U.S.C. 437d(a)(1)). 111.11 Section...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...Written questions under order (2 U.S.C. 437d(a)(1)). The...

  14. 11 CFR 111.14 - Witness fees and mileage (2 U.S.C. 437d(a)(5)).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...true Witness fees and mileage (2 U.S.C. 437d(a)(5)). 111.14 Section...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111.14 Witness fees and mileage (2 U.S.C. 437d(a)(5)). Witnesses...

  15. Hermen àutica objetiva? e sua apropria Ô úo na pesquisa emp §rica na írea da educa Ô úo

    Microsoft Academic Search

    Rita Amelia Teixeira Vilela; Juliane Noack-Napoles

    2010-01-01

    Este texto apresenta a metodologia de pesquisa social qualitativa denominada ?hermen àutica objetiva? desenvolvida pelo soci logo alem úo Ulrich Oeverman e aponta sua propriedade na pesquisa educacional. Derivada da tradi Ô úo interpretativa da Teoria Cr §tica de Theodor Adorno, a finalidade da an ílise ?hermen àutica objetiva? ø descortinar a l gica entre as estruturas de reprodu Ô

  16. Antnio Manuel Cruz Serra, reitor da Universidade de Lisboa, reconhece a importncia do Concurso Nacional de Inovao

    E-print Network

    Instituto de Sistemas e Robotica

    ;ENTREVISTA A ANTÓNIO MANUEL CRUZ SERRA | Reitor da Universidade de Lisboa "A responsabilidade social assumida importância, para a economia portuguesa, da capacidade de inova- ção tecnológica e empresarial a partir do transferência do conhecimento é essencial no impacto social dos resultados da investi- gação científica

  17. Vectra DA for the objective measurement of disease activity in patients with rheumatoid arthritis.

    PubMed

    Segurado, O G; Sasso, E H

    2014-01-01

    Quantitative and regular assessment of disease activity in rheumatoid arthritis (RA) is required to achieve treatment targets such as remission and to optimize clinical outcomes. To assess inflammation accurately, predict joint damage and monitor treatment response, a measure of disease activity in RA should reflect the pathological processes resulting in irreversible joint damage and functional disability. The Vectra DA blood test is an objective measure of disease activity for patients with RA. Vectra DA provides an accurate, reproducible score on a scale of 1 to 100 based on the concentrations of 12 biomarkers that reflect the pathophysiologic diversity of RA. The analytical validity, clinical validity, and clinical utility of Vectra DA have been evaluated for patients with RA in registries and prospective and retrospective clinical studies. As a biomarker-based instrument for assessing disease activity in RA, the Vectra DA test can help monitor therapeutic response to methotrexate and biologic agents and assess clinically challenging situations, such as when clinical measures are confounded by non-inflammatory pain from fibromyalgia. Vectra DA scores correlate with imaging of joint inflammation and are predictive for radiographic progression, with high Vectra DA scores being associated with more frequent and severe progression and low scores being predictive for non-progression. In summary, the Vectra DA score is an objective measure of RA disease activity that quantifies inflammatory status. By predicting risk for joint damage more effectively than conventional clinical and laboratory measures, it has the potential to complement these measures and optimise clinical decision making. PMID:25365086

  18. Essential Roles of Da Transactivation Domains in Neurogenesis and in E(spl)-Mediated Repression

    PubMed Central

    Zarifi, Ioanna; Kiparaki, Marianthi; Koumbanakis, Konstantinos A.; Giagtzoglou, Nikolaos; Zacharioudaki, Evanthia; Alexiadis, Anastasios; Livadaras, Ioannis

    2012-01-01

    E proteins are a special class of basic helix-loop-helix (bHLH) proteins that heterodimerize with many bHLH activators to regulate developmental decisions, such as myogenesis and neurogenesis. Daughterless (Da) is the sole E protein in Drosophila and is ubiquitously expressed. We have characterized two transcription activation domains (TADs) in Da, called activation domain 1 (AD1) and loop-helix (LH), and have evaluated their roles in promoting peripheral neurogenesis. In this context, Da heterodimerizes with proneural proteins, such as Scute (Sc), which is dynamically expressed and also contributes a TAD. We found that either one of the Da TADs in the Da/Sc complex is sufficient to promote neurogenesis, whereas the Sc TAD is incapable of doing so. Besides its transcriptional activation role, the Da AD1 domain serves as an interaction platform for E(spl) proteins, bHLH-Orange family repressors which antagonize Da/Sc function. We show that the E(spl) Orange domain is needed for this interaction and strongly contributes to the antiproneural activity of E(spl) proteins. We present a mechanistic model on the interplay of these bHLH factors in the context of neural fate assignment. PMID:22949507

  19. Biofortification of soybean meal: immunological properties of the 27 kDa ?-zein.

    PubMed

    Krishnan, Hari B; Jang, Sungchan; Kim, Won-Seok; Kerley, Monty S; Oliver, Melvin J; Trick, Harold N

    2011-02-23

    Legumes, including soybeans ( Glycine max ), are deficient in sulfur-containing amino acids, which are required for the optimal growth of monogastric animals. This deficiency can be overcome by expressing heterologous proteins rich in sulfur-containing amino acids in soybean seeds. A maize 27 kDa ?-zein, a cysteine-rich protein, has been successfully expressed in several crops including soybean, barley, and alfalfa with the intent to biofortify these crops for animal feed. Previous work has shown that the maize 27 kDa zein can withstand digestion by pepsin and elicit an immunogenic response in young pigs. By use of sera from patients who tested positive by ImmunoCAP assay for elevated IgE to maize proteins, specific IgE binding to the 27 kDa ?-zein is demonstrated. Bioinformatic analysis using the full-length and 80 amino acid sliding window FASTA searches identified significant sequence homology of the 27 kDa ?-zein with several known allergens. Immunoblot analysis using human serum that cross-reacts with maize seed proteins also revealed specific IgE-binding to the 27 kDa ?-zein in soybean seed protein extracts containing the 27 kDa zein. This study demonstrates for the first time the allergenicity potential of the 27 kDa ?-zein and the potential that this protein has to limit livestock performance when used in soybeans that serve as a biofortified feed supplement. PMID:21226519

  20. High resolution structure of cleaved Serpin 42 Da from Drosophila melanogaster

    PubMed Central

    2014-01-01

    Background The Drosophila melanogaster Serpin 42 Da gene (previously Serpin 4) encodes a serine protease inhibitor that is capable of remarkable functional diversity through the alternative splicing of four different reactive centre loop exons. Eight protein isoforms of Serpin 42 Da have been identified to date, targeting the protease inhibitor to both different proteases and cellular locations. Biochemical and genetic studies suggest that Serpin 42 Da inhibits target proteases through the classical serpin ‘suicide’ inhibition mechanism, however the crystal structure of a representative Serpin 42 Da isoform remains to be determined. Results We report two high-resolution crystal structures of Serpin 42 Da representing the A/B isoforms in the cleaved conformation, belonging to two different space-groups and diffracting to 1.7 Å and 1.8 Å. Structural analysis reveals the archetypal serpin fold, with the major elements of secondary structure displaying significant homology to the vertebrate serpin, neuroserpin. Key residues known to have central roles in the serpin inhibitory mechanism are conserved in both the hinge and shutter regions of Serpin 42 Da. Furthermore, these structures identify important conserved interactions that appear to be of crucial importance in allowing the Serpin 42 Da fold to act as a versatile template for multiple reactive centre loops that have different sequences and protease specificities. Conclusions In combination with previous biochemical and genetic studies, these structures confirm for the first time that the Serpin 42 Da isoforms are typical inhibitory serpin family members with the conserved serpin fold and inhibitory mechanism. Additionally, these data reveal the remarkable structural plasticity of serpins, whereby the basic fold is harnessed as a template for inhibition of a large spectrum of proteases by reactive centre loop exon ‘switching’. This is the first structure of a Drosophila serpin reported to date, and will provide a platform for future mutational studies in Drosophila to ascertain the functional role of each of the Serpin 42 Da isoforms. PMID:24758516

  1. Explaining caesarean section in Salvador da Bahia, Brazil.

    PubMed

    McCallum, Cecilia

    2005-03-01

    In Salvador da Bahia the caesarean section rate is excessive, as it is in Brazil as a whole. It is the standard form of delivery in private hospitals, though vaginal delivery still predominates in the public sector. This paper investigates the social context of these styles of childbirth, arguing that the connections between both sectors sustain this situation. Exploring the factors leading to the preference in private and insurance-funded maternity wards, it examines critically two diverging positions on the cause of the rate: that women's cultural preferences for abdominal birth lie behind it; or that obstetricians' self-interest is to blame. The paper critiques the theory of culture behind the first stance and questions the theoretical weight placed on individual action in the second. It argues that no particular social group is the principal cause of the excessive use of caesarean section to deliver babies. Rather, a host of factors converge in sustaining this practice. Finally, the paper stresses that the system as a whole, not any particular group, must be changed if the rate is to be lowered significantly. For this, political will is required. PMID:15787776

  2. Search for Metal Pollution in 81 DA White Dwarfs

    E-print Network

    Koester, Detlev; Girven, Jonathan; Farihi, Jay

    2012-01-01

    A total of 81 DA white dwarfs have been observed with the Cosmic Origins Spectrograph on the Hubble Space Telescope in a snapshot program. The targets were selected to be in the $T_{\\rm eff}$ range from 17000 - 25000 K, where optical metal lines become weak and difficult to detect. Because of the strong Si, C, and O resonance lines in the UV, this survey has a sensitivity that is comparable to that of the Keck/VLT searches for CaII K in cooler white dwarfs. These objects also have no convection zone and thus very short diffusion timescales, assuring that accretion is currently ongoing. The spectra have high resolution and in most cases fairly good S/N. About 60% of them show photospheric metal pollution, predominantly of Si, but in some cases additional metals are present. We report the results of a preliminary analysis and discuss the sources of the accreted matter and the possible r\\^ole of radiative levitation.

  3. DA WHITE DWARFS OBSERVED IN THE LAMOST PILOT SURVEY

    SciTech Connect

    Zhang Yueyang; Deng Licai; Liu Chao; Carrell, Kenneth; Yang Fan; Gao Shuang; Xu Yan; Li Jing; Zhang Haotong; Zhao Yongheng; Luo Ali; Bai Zhongrui; Yuan Hailong [Key Lab for Optical Astronomy, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 (China); Lepine, Sebastien [Department of Astrophysics, Division of Physical Sciences, American Museum of Natural History, Central Park West at 79th Street, New York, NY (United States); Newberg, Heidi Jo; Carlin, Jeffrey L. [Department of Physics, Applied Physics and Astronomy, Rensselaer Polytechnic Institute, 110 8th Street, Troy, NY 12180 (United States); Jin Ge [University of Science and Technology of China, Hefei 230026 (China)

    2013-08-01

    A total of {approx}640, 000 objects from the LAMOST pilot survey have been publicly released. In this work, we present a catalog of DA white dwarfs (DAWDs) from the entire pilot survey. We outline a new algorithm for the selection of white dwarfs (WDs) by fitting Sersic profiles to the Balmer H{beta}, H{gamma}, and H{delta} lines of the spectra, and calculating the equivalent width of the Ca II K line. Two thousand nine hundred sixty-four candidates are selected by constraining the fitting parameters and the equivalent width of the Ca II K line. All the spectra of candidates are visually inspected. We identify 230 DAWDs (59 of which are already included in the Villanova and SDSS WD catalogs), 20 of which are DAWDs with non-degenerate companions. In addition, 128 candidates are classified as DAWDs/subdwarfs, which means the classifications are ambiguous. The result is consistent with the expected DAWD number estimated based on the LEGUE target selection algorithm.

  4. AVALIAÇÃO DA PRESENÇA DE ENDOSSIMBIONTES Cardinium em DIFERENTES ESPÉCIES DE ARTRÓPODES.

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A presença de endossimbiontes do gênero Cardinium em alguns grupos de artrópodes foi recentemente relatada e relacionada com diversas alterações reprodutivas em seus hospedeiros, tais como feminilização de ácaros, partenogênese em parasitóides, incompatibilidade citoplasmática e aumento da fecundida...

  5. Expiration Da08/31/201 RECORD OF DAILY FLOW SCALE TESTS

    E-print Network

    Revised: 0 O Expiration Da08/31/201 RECORD OF DAILY FLOW SCALE TESTS Vessel Name: _________________________________ Date: _________________________________ Time test started: _________________________________ I. WEIGH FISH ON OBSERVER PLATFORM SCALE II. CALCULATE PERCENT ERROR OF FLOW SCALE Scale Indicator Begin Test

  6. 32 CFR 644.512 - DA-SBA joint set-aside determination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal Disposal of Standing Timber, Crops, and Embedded Gravel, Sand and Stone § 644.512 DA-SBA joint set-aside determination....

  7. XXVI SEMANA DE ENSINO, PESQUISA E EXTENSO IX SEMANA DA PEDAGOGIA 2014

    E-print Network

    Paraná, Universidade Federal do

    XXVI SEMANA DE ENSINO, PESQUISA E EXTENSÃO IX SEMANA DA PEDAGOGIA 2014 "Currículo e formação de Minicurso VI/ Oficina VIII/ Sessão de comunicação oral IX Mesa Redonda: 75 Anos do Curso de Pedagogia do

  8. PERCOLATION IN A CONTINUOUS TWO-DIMENSIONAL MEDIUM H. OTTAVI and J. P. GAY DA

    E-print Network

    Boyer, Edmond

    631 PERCOLATION IN A CONTINUOUS TWO-DIMENSIONAL MEDIUM H. OTTAVI and J. P. GAY DA Département d if the atoms of the 1 st gene- ration have neighbours themselves, by exploring the circle of each one. However

  9. 32 CFR 635.23 - DA Form 4833 (Commander's Report of Disciplinary or Administrative Action).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...commanders are responsible and accountable for completing DA Form 4833 with supporting documentation in all cases investigated by MPI, civilian detectives employed by the Department of the Army, and the PMO. The Battalion Commander or the first...

  10. 32 CFR 635.23 - DA Form 4833 (Commander's Report of Disciplinary or Administrative Action).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...commanders are responsible and accountable for completing DA Form 4833 with supporting documentation in all cases investigated by MPI, civilian detectives employed by the Department of the Army, and the PMO. The Battalion Commander or the first...

  11. 32 CFR 635.23 - DA Form 4833 (Commander's Report of Disciplinary or Administrative Action).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...commanders are responsible and accountable for completing DA Form 4833 with supporting documentation in all cases investigated by MPI, civilian detectives employed by the Department of the Army, and the PMO. The Battalion Commander or the first...

  12. 32 CFR 635.23 - DA Form 4833 (Commander's Report of Disciplinary or Administrative Action).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...commanders are responsible and accountable for completing DA Form 4833 with supporting documentation in all cases investigated by MPI, civilian detectives employed by the Department of the Army, and the PMO. The Battalion Commander or the first...

  13. A metabolite of acetaminophen covalently binds to the 56 kDa selenium binding protein.

    PubMed

    Pumford, N R; Martin, B M; Hinson, J A

    1992-02-14

    Acetaminophen is metabolized by cytochrome P450 to a reactive metabolite that covalently binds to proteins and this binding correlates with the hepatotoxicity. The major protein adduct was previously reported to be a 55 kDa protein that was detected on Western blots using antisera specific for 3-(cystein-S-yl)acetaminophen. In this study, the 55 kDa protein was isolated using a combination of ion exchange fast flow chromatography, hydroxyapatite HPLC and anion exchange HPLC. Amino acid sequences of 8 internal peptides from a trypsin digestion of the 55 kDa protein were found to have 97% homology with the deduced amino acid sequence from a cDNA that corresponds to a 56 kDa selenium binding protein. This is the first report of a specific protein to which a metabolite of acetaminophen covalently binds. PMID:1540179

  14. COMISSO CPA UFPR ATA DA REUNIO DE 04.09.07

    E-print Network

    Paraná, Universidade Federal do

    - PDI foram esclarecidas pela Professora Márcia Helena Mendonça, que sugeriu também que o PDI e PPI revisto, será inserido um parágrafo sobre a PDI 2006 ­ 2011, no parágrafo da missão (do Paraná e do Brasil

  15. Area Efficient D/A Converters For Accurate DC Operation Brandon Royce Greenley

    E-print Network

    Moon, Un-Ku

    . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 6.2 Mismatch Modeling For Area Optimization . . . . . . . . . . . . . . . . . . . . . . . 51 6Area Efficient D/A Converters For Accurate DC Operation by Brandon Royce Greenley A THESIS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42 5.1 Measurement Setup

  16. Boso de Higgs recebe Nobel da Fsica no ano a seguir descoberta p29 Nobel da Fsica de 2013 para teoria

    E-print Network

    Instituto de Sistemas e Robotica

    Bosão de Higgs recebe Nobel da Física no ano a seguir à descoberta p29 #12;Nobel da Física de 2013 para teoria (e prática) do bosão de Higgs Prémio distinguiu o belga François Englert e o britânico Peter Higgs, dois dos físicos teóricos que, há quase 50 anos, postularam a existência de uma partícula

  17. Diagnóstico de doença de Alzheimer no Brasil: avaliação cognitiva e funcional. Recomendações do Departamento Científico de Neurologia Cognitiva e do Envelhecimento da Academia Brasileira de Neurologia

    Microsoft Academic Search

    Ricardo Nitrini; Paulo Caramelli; Cássio Machado de Campos Bottino; Benito Pereira Damasceno; Sonia Maria Dozzi Brucki; Renato Anghinah

    2005-01-01

    RESUMO - As heterogeneidades educacional e cultural da população brasileira condicionam características p e c u l i a res ao diagnóstico da doença de Alzheimer (DA) no Brasil. Este consenso teve o objetivo de recomendar condutas baseadas em evidências para este diagnóstico. Foram avaliados sistematicamente artigos sobre o diagnóstico de DA no Brasil disponíveis no PUBMED ou LILACS. Para

  18. O Brincar Simbólico e a Organização Narrativa da Experiência de Vida na Criança Symbolic Play and the Narrative Organization of the Child's Life Experience

    Microsoft Academic Search

    André Guirland Vieira; Tania Mara Sper

    2003-01-01

    Resumo O presente trabalho estuda a narrativa e a imagem como elementos da linguagem do brincar simbólico. Para isto, uma criança foi acompanhada em um processo de psicoterapia por um período aproximado de um ano. O brincar simbólico da criança na caixa de areia - sandplay - foi analisado em termos da organização narrativa e da construção de significado a

  19. Temperature and Gravity Dependence of Trace Element Abundances in Hot DA White Dwarfs (94-EUVE-094)

    NASA Technical Reports Server (NTRS)

    Finley, David S.

    1998-01-01

    EUV spectroscopy has shown that DA white dwarfs hotter than about 45,000 K may contain trace heavy elements, while those hotter than about 50,000 K almost always have significant abundances of trace heavy elements. One of our continuing challenges is to identify and determine the abundances of these trace constituents, and then to relate the observed abundance patterns to the present conditions and previous evolutionary histories of the hot DA white dwarfs.

  20. Identification of a Streptococcus suis 60-kDa heat-shock protein using Western blotting

    Microsoft Academic Search

    Riad Benkirane; Marcelo G Gottschalk; J. Daniel Dubreuil

    1997-01-01

    This study was initiated to investigate the presence of stress or heat shock proteins in Streptococcus suis. SDS-PAGE and Western blotting using polyclonal and monoclonal antibodies directed against different bacterial heat shock proteins demonstrated cross-reactivity with a protein with an apparent molecular mass of 60 kDa in all S. suis serotypes tested. The 60-kDa cross-reactive protein was present in virulent

  1. Essential 170-kDa Subunit for Degradation of Crystalline Cellulose by Clostridium Cellulovorans Cellulase

    Microsoft Academic Search

    Oded Shoseyov; Roy H. Doi

    1990-01-01

    The cellulase complex from Clostridium cellulovorans has been purified and its subunit composition determined. The complex exhibits cellulase activity against crystalline cellulose as well as carboxymethylcellulase (CMCase) and cellobiohydrolase activities. Three major subunits are present with molecular masses of 170, 100, and 70 kDa. The 100-kDa subunit is the major CMCase, although at least four other, minor subunits show CMCase

  2. The effect of fluosol-DA and oxygenation status on the activity of cyclophosphamide in vivo

    Microsoft Academic Search

    Beverly A. Teicher; Terence S. Herman; Sylvia A. Holden; Kathleen N. S. Cathcart

    1988-01-01

    The addition of Fluosol-DA followed by carbogen breathing increased the antitumor effect of cyclophosphamide as measured by both tumor growth delay and tumor cell survival assays. Under air breathing conditions, cyclophosphamide (100 mg\\/kg) administered i.p. five times on alternate days produced a tumor growth delay in the FSaIIC fibrosarcoma of 8.0±0.8 days. Adding Fluosol-DA (0.3 ml) to treatment with cyclophosphamide

  3. PAN-DA and beyond: Data acquisition for the next generation experiments

    SciTech Connect

    Pordes, R.; Anderson, J.; Berg, D.; Berman, E.; Brown, D.; Dorries, T.; Mackinnon, B.; Meadows, J.; Moore, C.; Nicinski, T.; Oleynik, G.; Petravick, D.; Rechenmacher, R.; Sergey, G.; Slimmer, D.; Streets, J.; Vittone, M.; Votava, M.; Wilcer, N.; White, V.

    1991-06-01

    We report on the status of the PAN-DA data acquisition system presented at the last Real Time Conference. Since that time, PAN-DA has been successfully used in the fixed target program at Fermilab. We also report on the plans and strategies for development of a new data acquisition system for the next generation of fixed target experiments at Fermilab. 10 refs., 3 figs.

  4. FreeSoDA: A Web Services-Based Tool to Support Documentation in Distributed Projects

    Microsoft Academic Search

    Frank Padberg

    \\u000a FreeSoDA is a distributed document management system written in C# under .NET. FreeSoDA offers Web services for storing and extracting any kind of document (such as source files, plain text files, PDF files, UML\\u000a diagrams, or JPEG files) to and from a central database over the Internet. Users can link related documents with each other\\u000a in the database. To allow

  5. Cloning, characterization and functional studies of a human 40kDa catecholamine regulated protein

    Microsoft Academic Search

    Joseph Gabriele

    2006-01-01

    Previous reports by Nair and Mishra, have demonstrated the cloning and characterization of a central nervous system (CNS) specific 40kDa catecholamine regulated protein (CRP40) in bovine brain (Nair and Mishra 2001). Protein BLAST analysis has shown that the CRP40 amino acid sequence contains a significant amino acid homology with many heat shock proteins, specifically, heat shock protein 70 kDa (Hsp70)

  6. PARTICIPAÇÃO COMUNITÁRIA NO PLANEJAMENTO VIÁRIO DE ALGUNS BAIRROS DA CIDADE DE AMERICANA\\/SP 1

    Microsoft Academic Search

    Luzia Ferreira da Silva; Andrea Volpe-Filik; Ana Maria Liner; Pereira Lima; Ferreira da Silva Filho

    RESUMO O envolvimento da comunidade é um elemento fundamental para maior êxito no planejamento da arborização urbana. O presente trabalho teve os objetivos de, junto à população local, escolher espécies para plantio nas calçadas e colaborar no envolvimento das pessoas em solucionar os freqüentes problemas relacionados à educação ambiental. Na primeira fase constataram-se 2.551 indivíduos plantados, 76 espécies e 1.314

  7. Localization of 28-kDa peroxiredoxin in rat epithelial tissues and its antioxidant properties

    Microsoft Academic Search

    S. V. Novoselov; I. V. Peshenko; V. I. Popov; V. I Novoselov; M. F. Bystrova; V. J. Evdokimov; S. S. Kamzalov; M. I. Merkulova; T. M. Shuvaeva; V. M. Lipkin; E. E. Fesenko

    1999-01-01

    Peroxiredoxins are a novel family of antioxidant proteins that specifically prevent enzymes from metal-catalyzed oxidation. The localization of a member of the mono-cystein subfamily of peroxiredoxins, the 28-kDa protein, in different rat tissues and its antioxidant properties were investigated. By immunoblotting, the 28-kDa peroxiredoxin was found to be most highly concentrated in olfactory epithelium and present in all tissues tested

  8. CALCOLO COMBINATORIO 1. Modi di formare gruppi di k oggetti presi da n dati

    E-print Network

    Berti, Patrizia

    CALCOLO COMBINATORIO 1. Modi di formare gruppi di k oggetti presi da n dati 1.1. disposizioni primo elemento da mettere nel gruppo pu`o essere scelto in n modi (dall'insieme di tutti gli oggetti`a scelto), il terzo in n - 2, e cos`i via fino al k-esimo che pu`o essere scelto in n - k + 1 modi. Il

  9. Investigation of hydrophobic organic carbon (HOC) partitioning to 1 kDa fractionated municipal wastewater colloids.

    PubMed

    McPhedran, Kerry N; Seth, Rajesh; Drouillard, Ken G

    2013-03-19

    Natural organic matter from the aquatic environment passing a 1 kDa filter has been hypothesized to not contribute appreciably to hydrophobic organic compound (HOC) partitioning; however, to our knowledge this limit has not been verified experimentally for any sorbate/sorbent system. Presently, colloidal organic carbon (COC) < 1 kDa approached 70% of the total COC (<1.5 ?m) mass in primary effluent (PE) from a municipal wastewater treatment plant. Partitioning of HOCs 1,2,4,5-tetrachlorobenzene, pentachlorobenzene, and hexachlorobenzene to COC for both 1.5 ?m and 1 kDa filtrates of PE was investigated using the gas-stripping technique. Contrary to the hypothesis, significant HOC-COC partitioning to the 1 kDa filtrate was observed with organic carbon-normalized partitioning coefficients (logKCOC) of 4.30, 4.36, and 3.74 for 1,2,4,5-TeCB, PeCB, and HCB, respectively. Further, partitioning to COC < 1 kDa dominated the overall partitioning of the three chlorobenzenes in the 1.5 ?m filtrate, and the partitioning behavior did not follow the trend based on hydrophobicity (KOW). The results show that significant partitioning of HOC may occur to OC < 1 kDa and highlights the need for further experiments with other HOCs and COC characterization to better understand and explain the observed partitioning. PMID:23294454

  10. Vinpocetine and ?-tocopherol prevent the increase in DA and oxidative stress induced by 3-NPA in striatum isolated nerve endings.

    PubMed

    Herrera-Mundo, Nieves; Sitges, María

    2013-01-01

    Vinpocetine is a neuroprotective drug that exerts beneficial effects on neurological symptoms and cerebrovascular disease. 3-nitropropionic acid (3-NPA) is a toxin that irreversibly inhibits succinate dehydrogenase, the mitochondrial enzyme that acts in the electron transport chain at complex II. In previous studies in striatum-isolated nerve endings (synaptosomes), we found that vinpocetine decreased dopamine (DA) at expense of its main metabolite 3,4-dihydroxyphenylacetic acid (DOPAC), and that 3-NPA increased DA, reactive oxygen species (ROS), DA-quinone products formation, and decreased DOPAC. Therefore, in this study, the possible effect of vinpocetine on 3-NPA-induced increase in DA, ROS, lipid peroxidation, and DA-quinone products formation in striatum synaptosomes were investigated, and compared with the effects of the antioxidant ?-tocopherol. Results show that the increase in DA induced by 3-NPA was inhibited by both 25 ?M vinpocetine and 50 ?M ?-tocopherol. Vinpocetine, as ?-tocopherol, also inhibited 3-NPA-induced increase in ROS (as judged by DCF fluorescence), lipid peroxidation (as judged by TBA-RS formation), and DA-quinone products formation (as judged by the nitroblue tetrazolium reduction method). As in addition to the inhibition of complex II exerted by 3-NPA, 3-NPA increases DA-oxidation products that in turn can inhibit other sites of the respiratory chain, the drop in DA produced by vinpocetine and ?-tocopherol may importantly contribute to their protective action from oxidative damage, particularly in DA-rich structures. PMID:23121080

  11. Myelin management by the 18.5–kDa and 21.5–kDa classic myelin basic protein isoforms

    PubMed Central

    Harauz, George; Boggs, Joan M.

    2013-01-01

    The classic myelin basic protein (MBP) splice isoforms range in nominal molecular mass from 14 to 21.5 kDa, and arise from the gene in the oligodendrocyte lineage (Golli) in maturing oligodendrocytes. The 18.5-kDa isoform that predominates in adult myelin adheres the cytosolic surfaces of oligodendrocyte membranes together, and forms a two-dimensional molecular sieve restricting protein diffusion into compact myelin. However, this protein has additional roles including cytoskeletal assembly and membrane extension, binding to SH3-domains, participation in Fyn-mediated signaling pathways, sequestration of phosphoinositides, and maintenance of calcium homeostasis. Of the diverse post-translational modifications of this isoform, phosphorylation is the most dynamic, and modulates 18.5-kDa MBP’s protein-membrane and protein-protein interactions, indicative of a rich repertoire of functions. In developing and mature myelin, phosphorylation can result in microdomain or even nuclear targeting of the protein, supporting the conclusion that 18.5-kDa MBP has significant roles beyond membrane adhesion. The full-length, early-developmental 21.5-kDa splice isoform is predominantly karyophilic due to a non-traditional P-Y nuclear localization signal, with effects such as promotion of oligodendrocyte proliferation. We discuss in vitro and recent in vivo evidence for multifunctionality of these classic basic proteins of myelin, and argue for a systematic evaluation of the temporal and spatial distributions of these protein isoforms, and their modified variants, during oligodendrocyte differentiation. PMID:23398367

  12. Isolation and Characterization of a 32-kDa Fibrinolytic Enzyme (FE-32kDa) from Gloydius blomhoffii siniticus Venom

    PubMed Central

    Kim, Joung-Yoon; Lee, Seung-Bae; Kwon, Ki Rok; Choi, Suk-Ho

    2014-01-01

    Objectives: This study was undertaken to isolate a fibrinolytic enzyme from the snake venom of Gloydius blomhoffii siniticus and to investigate its enzymatic characteristics and hemorrhagic activity as a potential pharmacopuncture agent. Methods: The fibrinolytic enzyme was isolated by using chromatography, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and fibrin plate assay. The characteristics of the enzyme were investigated using fibrin plate assay, protein hydrolysis analysis, and hemorrhage assay. Its amino acid composition was determined. Results: The fibrinolytic enzyme with the molecular weight of 32kDa (FE-32kDa) from Gloydius blomhoffii siniticus showed a fibrin hydrolysis zone at the concentration of 0.2 mg/mL in the fibrin plate assay. The fibrin hydrolysis activity of the enzyme was inhibited completely by ethylenediaminetetraacetic acid (EDTA), ethyleneglycoltetraacetic acid (EGTA), and 1, 10-phenanthroline, thiothreitol and cysteine, and partially by phenylmethanesulfonylfluoride (PMSF). Metal ions such as Fe2+ and Hg2+ inhibited the fibrin hydrolysis completely, but Zn2+ enhanced it. FE-32kDa hydrolyzed ?-chain but did not hydrolyze ?-chain and ?-chain of fibrinogen. High-molecular-weight polypeptides of gelatin were hydrolyzed partially into low-molecular-weight polypeptides, but the extent of hydrolysis was limited. FE-32kDa induced hemorrhage beneath back skin of mice at the dose of 2 ?g. Conclusions: FE-32kDa is a ?-fibrin(ogen)olytic metalloprotease that requires Zn2+ for fibrinolytic activity and causes hemorrhage, suggesting that the enzyme is not appropriate for use as a clinical pharmacopuncture. PMID:25780689

  13. Characteristics of 26 kDa antigen of H. Pylori by Monoclonal Antibody.

    PubMed

    Ghahremani, Hossein; Farshad, Shohreh; Amini Najafabadi, Hossein; Kashanian, Susan; Momeni Moghaddam, Mohammad Amin; Moradi, Nariman; Paknejad, Maliheh

    2015-02-01

    Alkylhydroperoxide reductase (AhpC, the 26 kDa antigen) is one of the abundant antioxidant enzymes in Helicobacter pylori and seems to have a good potential for use in development of immunoassays to detect  H. pylori infection in clinical specimens. This study aimed to investigate some properties of this antigen by the produced monoclonal antibodies. Five established hybridoma cell lines secreting monoclonal antibodies (MAbs) against 26 kDa antigen of H. pylori were cultivated and MAbs were purified by affinity chromatography. Subsequently, MAbs were conjugated with biotin, and different combinations of capture and tracer antibodies used in sandwich ELISA. Immunoblotting of bacterial extracts were performed to estimate aggregation status of the antigen. Release of antigen from the cultivated bacteria on solid media was examined by sandwich ELISA, and also, existence of interference in fecal extract was investigated by immunoblotting and sandwich ELISA. Our findings showed that the MAbs against 26 kDa antigen of H. pylori could recognize three bands of nearly 25 kDa, 50 kDa, and 75 kDa in immunoblotting. This study also indicated presence of more antigens in the culture medium around the bacteria than the bacterial extract itself. The results of sandwich ELISA and immunoblotting on fecal extracts suggest the presence of interfering agents that prevent detection of antigen by antibody in ELISA but not in immunoblotting. In this study the oligomerization of the 26 kDa antigen, presence of interfering agents in stool matrix, and release of antigen to outside of bacteria, were demonstrated. PMID:25530147

  14. Crystal Structure of Bombyx mori Lipoprotein 6: Comparative Structural Analysis of the 30-kDa Lipoprotein Family

    PubMed Central

    Pietrzyk, Agnieszka J.; Bujacz, Anna; ?ochynska, Malgorzata; Jaskolski, Mariusz; Bujacz, Grzegorz

    2014-01-01

    The 30-kDa lipoprotein (LP) family of mulberry silkworm comprises major hemolymph proteins specific to the fifth instar larvae. The family consists of 46 members, 24 of which are referred to as typical 30-kDa LPs. To date, two crystal structures of 30-kDa LPs from Bombyx mori have been described (Bmlp3 and Bmlp7). Here, we present the crystal structure of Bmlp6, another 30-kDa LP member. Bmlp6 is comprised of two domains characteristic of this family, the VHS-type N-terminal domain and ?-trefoil C-terminal domain. The structures of the three 30-kDa LPs have been compared and a number of differences are noted, including loop conformation, the surface electrostatic potential, and the potential binding cavities. We discuss the observed structural differences in the light of the potential different roles of the particular 30-kDa LP members in silkworm physiology. PMID:25379889

  15. The effect of immunization with a 14-kDa streptococcal antigen on primate T cell and B cell responses.

    PubMed

    Fellowes, R; Fortune, F; Bergmeier, L A; Lehner, T

    1988-04-01

    A streptococcal antigen (SA) of 185 kDa was isolated from Streptococcus mutans and this antigen induced in vitro helper, suppressor and contrasuppressor activities with primate peripheral blood lymphocytes. The 185-kDa SA was then treated by sodium dodecyl sulfate and yielded a 4-kDa SA which was capable of eliciting only helper activity. We have now cleaved the 185-kDa SA with cyanogen bromide, in an attempt to identify suppressor and contrasuppressor determinants. A 14-kDa SA was separated from the cyanogen bromide digest and its ability to elicit T cell and B cell functional activities was tested in rhesus monkeys. Whereas the 185-kDa SA (and 4-kDa SA) elicited high serum anti-SA antibodies and the CD4 cells showed an increase in DNA synthesis, this was not demonstrable with the 14-kDa SA. However, the 14-kDa SA, unlike the 185-kDa SA, activated a significant proportion of CD4 and CD8 cells to bind the Vicia villosa lectin (VV) and this is a characteristic feature of contrasuppressor cells. We then studied the effect of sequential immunization of monkeys with the 14-kDa SA, followed by the 185-kDa SA. The results of this showed suppression of the CD4 proliferative response, in the presence of a normal antibody production. We suggest that the split tolerance between the T cell proliferative and B cell differentiating functions might be interpreted on the basis of suppressor CD8 cells inhibiting the CD4 proliferative phase and the VV-adherent CD8 cells contrasuppressing B cell antibody formation. PMID:3259185

  16. Constitutive activation of the 41-\\/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

    Microsoft Academic Search

    Rika Hoshino; Yuji Chatani; Takao Yamori; Takashi Tsuruo; Hiroya Oka; Osamu Yoshida; Yutaka Shimada; Shigeki Ari-i; Hiromi Wada; Jiro Fujimoto; Michiaki Kohno

    1999-01-01

    The 41-kDa and 43-kDa mitogen-activated protein (MAP) kinases play a pivotal role in the mitogenic signal transduction pathway and are essential components of the MAP kinase cascade, which includes MAP kinase kinase (MEK) and Raf-1. As aberrant activation of signal transducing molecules such as Ras and Raf-1 has been linked with cancer, we examined whether constitutive activation of the 41-\\/43-kDa

  17. Systematic design of a 14-bit 150MS\\/s CMOS current-steering D\\/A converter

    Microsoft Academic Search

    Geert Van der Plas; Jan Vandenbussche; Walter Daems; Antal van den Bosch; Georges G. E. Gielen; Willy M. C. Sansen

    2000-01-01

    This paper presents a D\\/A converter with a 14-bit intrinsic linearity in 0.5µm CMOS technology, which has been designed using a systematic design methodology for current-steering D\\/A converters. A flexible architecture is proposed for which the design parameters are calculated using a performance-driven top-down design methodology. The layout of the regular structure typical for D\\/A converters is automatically generated. Measurement

  18. Identification of a 28 kDa secretory protein from rat olfactory epithelium as a thiol-specific antioxidant

    Microsoft Academic Search

    I. V. Peshenko; V. I. Novoselov; V. A. Evdokimov; Yu. V. Nikolaev; S. S. Kamzalov; T. M. Shuvaeva; V. M. Lipkin; E. E. Fesenko

    1998-01-01

    The 28 kDa secretory protein is one of the abundant water-soluble proteins in olfactory epithelium of mammals. Analysis of partial amino acid sequence of the 28 kDa protein strongly suggested that it belongs to a new family of highly conserved antioxidant proteins requiring thiol for their antioxidant activity (TSA\\/AhpC family). In the present study, we found the 28 kDa protein

  19. The rare DAT coding variant Val559 perturbs DA neuron function, changes behavior, and alters in vivo responses to psychostimulants

    PubMed Central

    Mergy, Marc A.; Gowrishankar, Raajaram; Gresch, Paul J.; Gantz, Stephanie C.; Williams, John; Davis, Gwynne L.; Wheeler, C. Austin; Stanwood, Gregg D.; Hahn, Maureen K.; Blakely, Randy D.

    2014-01-01

    Despite the critical role of the presynaptic dopamine (DA) transporter (DAT, SLC6A3) in DA clearance and psychostimulant responses, evidence that DAT dysfunction supports risk for mental illness is indirect. Recently, we identified a rare, nonsynonymous Slc6a3 variant that produces the DAT substitution Ala559Val in two male siblings who share a diagnosis of attention-deficit hyperactivity disorder (ADHD), with other studies identifying the variant in subjects with bipolar disorder (BPD) and autism spectrum disorder (ASD). Previously, using transfected cell studies, we observed that although DAT Val559 displays normal total and surface DAT protein levels, and normal DA recognition and uptake, the variant transporter exhibits anomalous DA efflux (ADE) and lacks capacity for amphetamine (AMPH)-stimulated DA release. To pursue the significance of these findings in vivo, we engineered DAT Val559 knock-in mice, and here we demonstrate in this model the presence of elevated extracellular DA levels, altered somatodendritic and presynaptic D2 DA receptor (D2R) function, a blunted ability of DA terminals to support depolarization and AMPH-evoked DA release, and disruptions in basal and psychostimulant-evoked locomotor behavior. Together, our studies demonstrate an in vivo functional impact of the DAT Val559 variant, providing support for the ability of DAT dysfunction to impact risk for mental illness. PMID:25331903

  20. Metagonimus yokogawai: a 100-kDa Somatic Antigen Commonly Reacting with Other Trematodes

    PubMed Central

    Park, Young-Jin; Park, Jeong-Hyun; Chai, Jong-Yil

    2014-01-01

    This study was undertaken to characterize the properties of a 100 kDa somatic antigen from Metagonimus yokogawai. Monoclonal antibodies (mAbs) were produced against this 100 kDa antigen, and their immunoreactivity was assessed by western blot analysis with patients' sera. The mAbs against the 100 kDa antigen commonly reacted with various kinds of trematode antigens, including intestinal (Gymnophalloides seoi), lung (Paragonimus westermani), and liver flukes (Clonorchis sinensis and Fasciola hepatica). However, this mAb showed no cross-reactions with other helminth parasites, including nematodes and cestodes. To determine the topographic distribution of the 100 kDa antigen in worm sections, indirect immunoperoxidase staining was performed. A strong positive reaction was observed in the tegumental and subtegumental layers of adult M. yokogawai and C. sinensis. The results showed that the 100 kDa somatic protein of M. yokogawai is a common antigen which recognizes a target epitope present over the tegumental layer of different trematode species. PMID:24850966

  1. Ionophorous properties of the 13 000-Da fragment from sarcoplasmic reticulum (Ca2+ + Mg2+)-ATPase.

    PubMed

    Herrmann, T R; Shamoo, A E

    1983-08-10

    The 25 000-Da tryptic fragment from rabbit muscle sarcoplasmic reticulum (Ca2+ + Mg2+)-ATPase was subjected to cyanogen bromide digestion, and the four fragments isolated. Only the 13 000-Da fragment induced ionophorous activity in planar thin lipid membranes made with 5:1 (w/w) phosphatidylcholine/cholesterol in decane. The membranes became cation selective, with a selectivity sequence among divalent of Mn2+ greater than Ca2+ greater than Ba2+ greater than Sr2+ greater than Mg2+. This is different from that of the 25 000-Da fragment (A.E. Shamoo, 1978, J. Memb. Biol. 43, 227-242), it's 'parent' 55 000-Da fragment, and the intact enzyme, all of which have the same selectivity sequence. The inhibitory effects of Hg2+, Cd2+ and Zn2+ were also examined. All were inhibitory, with Zn2+ being the most effective of these. The heavy-metal-induced inhibition of Ca2+ conductance could be reversed by selective chelation of the heavy metals by EDTA. From changes in the selectivity as well as changes in heavy-metal-induced inhibition behavior, we conclude that the ion transport site of the 13 000-Da fragment may not be the same site as that of the parent fragment. It is either a different site altogether or has been physically modified by peptide cleavage. PMID:6135449

  2. Low strain, long life creep fatigue of AF2-1DA and INCO 718

    SciTech Connect

    Thakker, A.B.; Cowles, B.A.

    1983-04-01

    Two aircraft turbine disk alloys, GATORIZED AF2-DA and INCO 718 were evaluated for their low strain long life creep-fatigue behavior. Static (tensile and creep rupture) and cyclic properties of both alloys were characterized. The cntrolled strain LCF tests were conducted at 760 C (1400 F) and 649 C (1200 F) for AF2-1DA and INCO 718, respectively. Hold times were varied for tensile, compressive and tensile/compressive strain dwell (relaxation) tests. Stress (creep) hold behavior of AF2-1DA was also evaluated. Generally, INCO 718 exhibited more pronounced reduction in cyclic life due to hold than AF2-1DA. The percent reduction in life for both alloys for strain dwell tests was greater at low strain ranges (longer life regime). Changing hold time from 0 to 0.5, 2.0 and 15.0 min. resulted in corresponding reductions in life. The continuous cycle and cyclic/dwell initiation failure mechanism was predominantly transgranular for AF2-1DA and intergranular for INCO 718.

  3. Simulation of cometary infrared spectra using laboratory extinction data of carbonaceous materials

    NASA Astrophysics Data System (ADS)

    Colangeli, L.; Bussoletti, E.; Papoular, R.; Mennella, V.

    1990-07-01

    Laboratory observations of the behavior of hydrogenated amorphous carbon (HAC) and the vitreous homogeneous organic compound vitrine may furnish a key to the identification of the 3.3-3.4 micron bands encountered in Comet Halley spectra between 3 and 4 microns. When the HAC annealing temperature rises, or when the rank of vitrines increases, a similar change occurs in the structure of these carbonaceous materials from a prevalent aliphatic to a dominant aromatic character. In situ mass spectrometry investigations of CHON particles conducted by Giotto and both Vega 1 and 2 appear to confirm the similarity of physical structure between carbonaceous particles and those observed in the laboratory.

  4. Recombinant Gluconacetobacter diazotrophicus containing Cry1Ac gene codes for 130-kDa toxin protein.

    PubMed

    Subashini, M; Moushumi Priya, A; Sundarakrishnan, B; Jayachandran, S

    2011-01-01

    Recombinant Gluconacetobacter diazotrophicus containing Cry1Ac gene from Bacillus thuringiensis var. kurstaki borne on pKT230, shuttle vector, was generated. PCR amplification of Cry1Ac gene present in recombinant G. diazotrophicus yielded a 278-bp DNA product. The nitrogenase assay has revealed that the recombinant G. diazotrophicus in sugarcane stem produced similar levels of nitrogenase compared to wild-type G. diazotrophicus. The presence of 130-kDa protein in apoplastic fluid from sugarcane stem harvested from pots inoculated with recombinant G. diazotrophicus shows that the translocated G. diazotrophicus produces 130-kDa protein which is recognized by the hyperimmune antiserum raised against 130-kDa protein. The first instar Eldana saccharina neonate larvae that fed on artificial medium containing recombinant G. diazotrophicus died within 72 h after incubation. PMID:21934327

  5. The Da Vinci European BioBank: A Metabolomics-Driven Infrastructure

    PubMed Central

    Carotenuto, Dario; Luchinat, Claudio; Marcon, Giordana; Rosato, Antonio; Turano, Paola

    2015-01-01

    We present here the organization of the recently-constituted da Vinci European BioBank (daVEB, https://www.davincieuropeanbiobank.org/it). The biobank was created as an infrastructure to support the activities of the Fiorgen Foundation (http://www.fiorgen.net/), a nonprofit organization that promotes research in the field of pharmacogenomics and personalized medicine. The way operating procedures concerning samples and data have been developed at daVEB largely stems from the strong metabolomics connotation of Fiorgen and from the involvement of the scientific collaborators of the foundation in international/European projects aimed to tackle the standardization of pre-analytical procedures and the promotion of data standards in metabolomics. PMID:25913579

  6. Identification of a 27 kDa protein in patients with anaphylactic reactions to mango.

    PubMed

    Renner, R; Hipler, C; Treudler, R; Harth, W; Süss, A; Simon, J C

    2008-01-01

    Mango fruit has become increasingly popular in recent years. We report on 2 patients who developed anaphylactic reactions after the ingestion of fresh mango. Allergy to mango was confirmed by a positive skin prick test result and positive cellular allergen stimulation test results. Neither of the patients had detectable mango-specific immunoglobulin (Ig) E levels. Results were validated by sodium dodecyl sulfate polyacrylamide gel electrophoresis immunoblotting and analyzed using Quantiscan.We identified 2 major allergens with a molecular weight of 27 kDa in both patients, in addition to a 15 kDa allergen in 1 patient and a 32 kDa allergen in the other. Currently available IgE systems seem to be lacking these mango allergens and as such are probably unsuitable for diagnosing type 1 sensitization to mango. Skin prick testing with fresh mango fruit therefore seems to be a much more reliable test method for clinical practice. PMID:19123442

  7. Lichen planus pemphigoides with circulating autoantibodies against 200 and 180 kDa epidermal antigens.

    PubMed

    Yoon, K H; Kim, S C; Kang, D S; Lee, I J

    2000-01-01

    We describe a case of lichen planus pemphigoides with circulating autoantibodies against 200 and 180 kDa epidermal antigens. A 24-year-old man presented pruritic erythematous patches with occasional central blister formation on the face, neck, and trunk and erythematous hyperkeratotic patches on the elbows and feet for 10 months. Histopathological findings of the neck and plantar lesions were consistent with lichen planus. Direct immunofluorescence studies from both lesions showed a linear deposition of IgG and C3 and cytoid bodies along the basement membrane zone. Indirect immunofluorescence studies demonstrated circulating IgG antibodies deposited on the epidermal side of salt-split skin. Immunoblot analysis using epidermal extract showed that the patient's serum reacted with 180 kDa bullous pemphigoid antigen (BPAG2) and a 200 kDa antigen. The cutaneous lesions almost cleared with a low dose of prednisolone and acitretin. PMID:10725820

  8. Detection of trace helium in G104 - 27, a 26,000 K DA white dwarf

    NASA Technical Reports Server (NTRS)

    Holberg, J. B.; Kidder, K. M.; Wesemael, F.

    1990-01-01

    The detection of the He I 4471 A feature in the moderately hot DA white dwarf G104 - 27 places this star within the rather sparse class of DAB white dwarfs. It does not appear possible, on the basis of the present data, to distinguish between a stratified and a homogeneously mixed atmosphere. While a stratified structure would be natural for a DA white dwarf, G104 - 27 resides near the red edge of the DB gap, in a region where DA stars could transform into DB stars through convective mixing in the underlying He envelope and thereby destroy envelope stratification. Both atmospheres are consistent with the existing soft X-ray flux limit for this star.

  9. Goldstone Radar Images of Near-Earth Asteroid 2012 DA14

    NASA Astrophysics Data System (ADS)

    Benner, Lance A.; Brozovic, M.; Giorgini, J. D.; Jao, J. S.; Lee, C. G.; Busch, M. W.; Slade, M. A.

    2013-10-01

    2012 DA14 made an extremely close approach within 0.00023 AU (0.09 lunar distances) on February 15, 2013. This was the closest encounter known in advance by a near-Earth asteroid with an absolute magnitude brighter than 25. We took advantage of this opportunity to image 2012 DA14 at Goldstone on February 16, 18, and 19 as the asteroid was receding from Earth. The imaging started at 00:46 UTC, slightly more than five hours after the closest approach, when the asteroid was at a distance of 0.00088 AU (0.34 lunar distances). The echoes were extraordinarily strong and we obtained some of the highest signal-to-noise ratios for any near-Earth asteroid ever observed at Goldstone. The images achieved resolutions as fine as 3.75 m x 0.00625 Hz that spatially resolve 2012 DA14 into a few dozen pixels; however, due to the diminutive dimensions of the asteroid, even this extremely high resolution is insufficient to show detailed surface features. The images indicate that 2012 DA14 is an asymmetric, angular, and elongated object with major axes of roughly 40 x 20 meters. The sequence of images obtained on February 16 spans 7.8 hours, during which the orientation of the asteroid appeared to complete close to one full rotation, suggesting that the rotation period is somewhat longer than ~8 hours. Radar speckle tracking with the Very Large Array and elements of the Very Long Baseline array show that 2012 DA14 has a relatively low obliquity and constrain the amplitude of any non-principal axis wobble after the flyby to be < 30 degrees. 2012 DA14 is among the smallest near-Earth asteroids ever spatially resolved by radar and it highlights the substantial scientific potential of the new chirp imaging system at Goldstone.

  10. Performance of a 27 kDa Fasciola hepatica Antigen in the Diagnosis of Human Fascioliasis

    PubMed Central

    Shafiei, Reza; Sarkari, Bahador; Sadjjadi, Seyed Mahmoud

    2015-01-01

    Background: Serological diagnosis, based on antigenic fractions of the parasite can be used for the early diagnosis of human fascioliasis. The current study aimed to evaluate the efficacy of a 27 kDa immunodominant antigen of Fasciola hepatica adult worms, in an indirect enzyme-linked immunosorbent assay (ELISA) system for serological diagnosis of human fascioliasis. Materials and Methods: The immunodiagnosis of human fascioliasis, using a 27 kDa immunodominant antigen, purified from F. hepatica somatic antigens (SAs), was evaluated by Western blotting and ELISA with sera samples of human fascioliasis patients, healthy controls and patients with other parasitic infections. Results: Using western blotting, from 12 sera of fascioliasis patients, 11 sera (91.6%) detected the 27 kDa subunit. None of 30 samples from healthy controls or 32 sera from nonfascioliasis patients reacted with the 27 kDa antigen. Accordingly, sensitivity and specificity of the system was found to be 91.6% and 100%, respectively. The 27 kDa antigen was purified from the SAs and was used in an indirect ELISA system. Of 15 sera of fascioliasis patients, all (100%) were found to be positive by ELISA whereas only 4 cases (6.25%) of nonfascioliasis patients or healthy controls were false-positive by this system. Accordingly, the sensitivity and specificity of the test were 100% and 93.6%, respectively. Conclusion: Findings of this study demonstrated that both Western blotting and the indirect ELISA, based on the 27 kDa subunit of F. hepatica SA, are reliable methods for serodiagnosis of human fascioliasis. PMID:25949054

  11. A ORGANIZAÇÃO DE PEQUENOS PRODUTORES DE LEITE DO NOROESTE DO RIO GRANDE DO SUL: APORTES NA LENTE DA NOVA ECONOMIA INSTITUCIONAL (NEI) E DA GESTÃO DE CADEIAS DE SUPRIMENTOS (GCS)

    Microsoft Academic Search

    Alessandro Porporatti Arbage; Neimar Damian Peroni; Pedro Urubatan Neto Da Costa

    2008-01-01

    O artigo propõe a admissão das abordagens da Nova Economia Institucional e a Gestão de Cadeia de Suprimentos, até então não trabalhadas pelos extensionistas da “Associação Riograndense de Empreendimentos de Assistência Técnica de Extensão Rural – EMATER\\/RS”, na interface com organizações de pequenos produtores rurais de leite do noroeste do Estado do Rio Grande do Sul. O esboço tem como

  12. Model Atmosphere Analysis of the Magnetic Field in Cool, Hydrogen-line (DA) White Dwarfs

    NASA Astrophysics Data System (ADS)

    Rolland, B.; Bergeron, P.

    2015-06-01

    We present a detailed model atmosphere analysis of the strength and geometry of the magnetic field in cool, hydrogen-line (DA) white dwarfs using offset dipole models. We show in particular that most stars in our sample can only be accounted for if they are unresolved double white dwarf systems, one of which even consists of two magnetic DA stars. Our results also suggest that the magnetic field in these cool white dwarfs cannot have a fossil origin, and must be somehow generated by some mechanism that remains unexplained at this stage.

  13. Solubilization of insoluble inorganic phosphate by Burkholderia cepacia DA23 isolated from cultivated soil

    PubMed Central

    Song, Ok-Ryul; Lee, Seung-Jin; Lee, Yong-Seok; Lee, Sang-Cheol; Kim, Keun-Ki; Choi, Yong-Lark

    2008-01-01

    A mineral phosphate solubilizing bacterium, Burkholderia cepacia DA23 has been isolated from cultivated soils. Phosphate-solubilizing activities of the strain against three types of insoluble phosphate were quantitatively determined. When 3% of glucose concentration was used for carbon source, the strain had a marked mineral phosphate-solubilizing activity. Mineral phosphate solubilization was directly related to the pH drop by the strain. Analysis of the culture medium by high pressure liquid chromatography identified gluconic acid as the main organic acid released by Burkholderia cepacia DA23. Gluconic acid production was apparently the result of the glucose dehydrogenase activity and glucose dehydrogenase was affected by phosphate regulation. PMID:24031195

  14. Aerodynamic design of the Cal Poly Da Vinci Human-Powered Helicopter

    NASA Technical Reports Server (NTRS)

    Larwood, Scott; Saiki, Neal

    1990-01-01

    This paper will discuss the methodology used in designing the rotor and drive propellers for the third generation Cal Poly Da Vinci Human-Powered Helicopter. The rotor was designed using a lifting surface, uniform inflow hover analysis code and the propeller was designed using a minimum induced-loss method. Construction, geometry, and operating considerations are discussed as they impact the designs. Optimization of the design performance is also explained. The propellers were tested in a wind tunnel and results are compared with theoretical data. Successful flight tests of the Da Vinci III are discussed.

  15. Comparison of Abbott and Da-an real-time PCR for quantitating serum HBV DNA

    PubMed Central

    Qiu, Ning; Li, Rui; Yu, Jian-Guo; Yang, Wen; Zhang, Wei; An, Yong; Li, Tong; Liu, Xue-En; Zhuang, Hui

    2014-01-01

    AIM: To compare the performance of the Da-an real-time hepatitis B virus (HBV) DNA assay and Abbott RealTime HBV assay. METHODS: HBV DNA standards as well as a total of 180 clinical serum samples from patients with chronic hepatitis B were measured using the Abbott and Da-an real-time polymerase chain reaction (PCR) assays. Correlation and Bland-Altman plot analysis was used to compare the performance of the Abbott and Da-an assays. The HBV DNA levels were logarithmically transformed for analysis. All statistical analyses were performed using SPSS for Windows version 18.0. The correlation between the two assays was analyzed by Pearson’s correlation and linear regression. The Bland-Altman plots were used for the analysis of agreement between the two assays. A P value of < 0.05 was considered statistically significant. RESULTS: The HBV DNA values measured by the Abbott or Da-an assay were significantly correlated with the expected values of HBV DNA standards (r = 0.999, for Abbott; r = 0.987, for Da-an, P < 0.001). A Bland-Altman plot showed good agreement between these two assays in detecting HBV DNA standards. Among the 180 clinical serum samples, 126 were quantifiable by both assays. Fifty-two samples were detectable by the Abbott assay but below the detection limit of the Da-an assay. Moreover, HBV DNA levels measured by the Abbott assay were significantly higher than those of the Da-an assay (6.23 ± 1.76 log IU/mL vs 5.46 ± 1.55 log IU/mL, P < 0.001). A positive correlation was observed between HBV DNA concentrations determined by the two assays in 126 paired samples (r = 0.648, P < 0.001). One hundred and fifteen of 126 (91.3%) specimens tested with both assays were within mean difference ± 1.96 SD of HBV DNA levels. CONCLUSION: The Da-an assay presented lower sensitivity and a narrower linear range as compared to the Abbott assay, suggesting the need to be improved. PMID:25206280

  16. The 119 kDa and 124 kDa polyproteins of arabis mosaic nepovirus (isolate S) are encoded by two distinct RNA2 species.

    PubMed

    Loudes, A M; Ritzenthaler, C; Pinck, M; Serghini, M A; Pinck, L

    1995-04-01

    Arabis mosaic virus (ArMV) is a nepovirus that is serologically distantly related to grapevine fanleaf virus (GFLV). Both ArMV and GFLV induce grapevine degeneration disease. Several ArMV isolates, unlike isolates of GFLV, produce upon in vitro translation of RNA2 a polyprotein (P2) that forms a double band in polyacrylamide-SDS gels. Cloning of full-length copies of RNA2 of an ArMV isolate from grapevine (ArMV-S) revealed that this isolate contained two RNA2s of different length, called RNA2-U and RNA2-L. The two species were not readily separated by electrophoresis of the virion RNA under denaturing gel electrophoresis conditions but could be distinguished by analysis of primer extension and in vitro translation products. The size difference of the two RNA2s is due mostly if not exclusively to differences in their coding regions. The 124 kDa RNA2-U-encoded polyprotein P2' and the 119 kDa RNA2-L-encoded polyprotein P2", which co-migrate, respectively, with the upper and lower polyprotein bands produced by RNA2 of ArMV-S, were more than 95% identical except in their N-terminal domains. In vitro maturation experiments and sequence comparisons indicate that the N-terminal products of P2' and P2" have a molecular mass of 31 kDa and 26 kDa. The genomic organization proposed is similar to that of GFLV RNA2. PMID:9049336

  17. Recognition of the 300-kDa mannose 6-phosphate receptor cytoplasmic domain by 47-kDa tail-interacting protein

    Microsoft Academic Search

    Joke G. Orsel; Paul M. Sincock; Jeffrey P. Krise; Suzanne R. Pfeffer

    2000-01-01

    Tail-interacting 47-kDa protein (TIP47) binds the cytoplasmic domains of the cation-dependent (CD) and cation-independent (CI) mannose 6-phosphate receptors (MPRs) and is required for their transport from endosomes to the Golgi complex. TIP47 recognizes a phenylalanine-tryptophan signal in the CD-MPR. We show here that TIP47 interaction with the 163-residue CI-MPR cytoplasmic domain is highly conformation dependent and requires CI-MPR residues that

  18. 32 CFR Appendix D to Part 623 - Certificate for Signature by an Alternate (DA Form 4881-1-R)

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 2010-07-01 2010-07-01 true Certificate for Signature by an Alternate (DA Form 4881-1-R) D Appendix D...623, App. D Appendix D to Part 623—Certificate for Signature by an Alternate (DA Form 4881-1-R)...

  19. 32 CFR Appendix D to Part 623 - Certificate for Signature by an Alternate (DA Form 4881-1-R)

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 2013-07-01 2013-07-01 false Certificate for Signature by an Alternate (DA Form 4881-1-R) D Appendix D...623, App. D Appendix D to Part 623—Certificate for Signature by an Alternate (DA Form 4881-1-R)...

  20. 32 CFR Appendix D to Part 623 - Certificate for Signature by an Alternate (DA Form 4881-1-R)

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 2014-07-01 2014-07-01 false Certificate for Signature by an Alternate (DA Form 4881-1-R) D Appendix D...623, App. D Appendix D to Part 623—Certificate for Signature by an Alternate (DA Form 4881-1-R)...

  1. 32 CFR Appendix D to Part 623 - Certificate for Signature by an Alternate (DA Form 4881-1-R)

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 2012-07-01 2009-07-01 true Certificate for Signature by an Alternate (DA Form 4881-1-R) D Appendix D...623, App. D Appendix D to Part 623—Certificate for Signature by an Alternate (DA Form 4881-1-R)...

  2. 32 CFR Appendix D to Part 623 - Certificate for Signature by an Alternate (DA Form 4881-1-R)

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 2011-07-01 2009-07-01 true Certificate for Signature by an Alternate (DA Form 4881-1-R) D Appendix D...623, App. D Appendix D to Part 623—Certificate for Signature by an Alternate (DA Form 4881-1-R)...

  3. La valutazione dei corsi da parte degli studenti: confronto fra carta e web Lorenzo Bernardi e Gianpiero Dalla Zuanna

    E-print Network

    Cesare, Bernardo

    La valutazione dei corsi da parte degli studenti: confronto fra carta e web Lorenzo Bernardi e procedura informatica di valutazione dei corsi da parte degli studenti. Di concerto con l'Ateneo, la Facoltà sovrapposizione effettiva è di soli 75 insegnamenti, tredici dei quali non considerati in quanto in almeno una

  4. CORRELAÇÃO CANÔNICA DAS CARACTERÍSTICAS QUÍMICAS E FÍSICAS DA MADEIRA DE CLONES DE Eucalyptus grandis e Eucalyptus saligna

    Microsoft Academic Search

    Paulo Fernando Trugilho; José Tarcisio Lima; Fábio Akira Mori

    2003-01-01

    RESUMO: A análise de correlação canônica mede a existência e a intensidade da associação entre dois grupos de variáveis. O objetivo do presente trabalho foi avaliar a correlação canônica entre as características químicas, físicas e dimensionais das fibras da madeira em clones de Eucalyptus grandis e Eucalyptus saligna, visando verificar a interdependência entre os grupos de variáveis estudadas. Pelas análises

  5. RESOLUO N 30/13-COPLAD Aprova o Regimento do Setor de Artes, Comunicao e Design da

    E-print Network

    Paraná, Universidade Federal do

    RESOLUÇÃO Nº 30/13-COPLAD Aprova o Regimento do Setor de Artes, Comunicação e Design da do Setor de Artes, Comunicação e Design (SACOD) da Universidade Federal do Paraná (UFPR), nos seguintes termos: TÍTULO I Das Disposições Preliminares Art. 2o O Setor de Artes, Comunicação e Design

  6. CONCURSO PBLICO PARA PROVIMENTO DE VAGAS EM CARGOS DE ASSISTENTE DE PESQUISA DA CARREIRA DE PESQUISA -Edital 01/2014

    E-print Network

    91,00 54,20 1306 JORGE LUIS GOMES 93,40 58,00 1155 LIGIA ALVES DA SILVA 68,00 53,70 1116 LUIZ EDUARDO CRISTINA LEMOS DA SILVA 67,60 49,00 1360 NICOLAS MOISES CRUZ SALVADOR 57,80 36,00 CÓDIGO: PQ04 CARGO

  7. Cr AGE OF A HIGHLY-EVOLVED, IGNEOUS LITHOLOGY IN POLYMICT UREILITE DaG 165. 1

    E-print Network

    Cohen, Barbara Anne

    53 Mn-53 Cr AGE OF A HIGHLY-EVOLVED, IGNEOUS LITHOLOGY IN POLYMICT UREILITE DaG 165. 1 C new data for 53 Mn-53 Cr systematics of a feldspathic igneous clast in the polymict ureilite DaG 165 with derivation from the ureilite parent body. 53 Mn-53 Cr Systematics: Glass in clast-19 is Mn-rich, consistent

  8. Adequação da metodologia do teste de deterioração controlada para sementes de brócolis (Brassica oleracea L. - var. itálica)

    Microsoft Academic Search

    Elisabeth Aparecida Furtado de Mendonça; Nilza Patrícia Ramos; Simone Aparecida Fessel

    2003-01-01

    2 RESUMO - A eficiência dos testes de vigor na avaliação da qualidade de sementes, depende da sua padronização para as diferentes espécies. Neste contexto, os objetivos deste trabalho foram elaborar as curvas de absorção de água para determinar o período necessário ao ajuste do teor de água das sementes e aprimorar o teste de deterioração controlada para sementes de

  9. Antnio Cruz Serra foi o nico candidato ao cargo de reitor da nova Universidade de Lisboa Reitor de megauniversidade

    E-print Network

    Instituto de Sistemas e Robotica

    António Cruz Serra foi o único candidato ao cargo de reitor da nova Universidade de Lisboa Reitor Técnica para a liderança da nova instituição e na bagagem traz a aposta na investigação, como forma de nova megaestrutura, que vai ter no seu conjunto 48 mil alunos em todos os graus de ensino. Marcelo

  10. O IMPACTO DA POLÍTICA FISCAL LOCAL SOBRE O CRESCIMENTO ECONÔMICO: UM ESTUDO EM CROSS-SECTION PARA OS MUNICÍPIOS POTIGUARES

    Microsoft Academic Search

    Francisco Soares de Lima

    Resumo: Este trabalho tem como objetivo estudar os efeitos da política fiscal local no crescimento econômico dos municípios do Rio Grande do Norte. A pesquisa é fundamentada teoricamente com base no modelo de Crescimento Endógeno e na Nova Geografia Econômica (NGE). Foi utilizado um modelo econométrico baseado no proposto por Oliveira (2006), que visa estimar o efeito da política fiscal

  11. AÇÃO EXTENSIONISTA DA EMPAER FRENTE À NOVA PNATER: UMA ANÁLISE A PARTIR DO ASSENTAMENTO GUAPIRAMA, CAMPO NOVO DO PARECIS - MT

    Microsoft Academic Search

    Gilmar Laforga; Andreia De Oliveira Vieira

    2008-01-01

    O modelo de agricultura ainda praticado continua a causar impactos negativos como a perda de solo, erosão genética, contaminação do solo e da água entre muitos outros efeitos. Considerando-se esse cenário e assim buscar minimizar estes processos, foi criada a Política Nacional de Assistência Técnica e Extensão Rural – PNATER, que orienta uma extensão rural baseada nos princípios epistemológico da

  12. Identification of a Bacillus thuringiensis Cry8Da toxin-binding glucosidase from the adult Japanese beetle, Popillia japonica.

    PubMed

    Yamaguchi, Takuya; Bando, Hisanori; Asano, Shin-ichiro

    2013-06-01

    Cry8Da from Bacillus thuringiensis galleriae SDS-502 has insecticidal activity against both the larvae and adult Japanese beetle (Popillia japonica Newman). The receptor determines the specificity of the insecticidal activity of Cry proteins and hence, in order to reveal the mode of action of Cry toxin, receptor identification is a necessary step. However, a receptor for Cry8-type toxin has not been identified in the Scarabaeidae family of insects. Therefore, we aimed to identify the receptor of Cry8Da toxin in adult P. japonica BBMV. A ligand blot showed the Cry8Da toxin only bound to a 150kDa protein in the BBMV of adult P. japonica. In order to identify the Cry8Da toxin binding protein, it was purified by column chromatography and three internal amino acid sequences were determined. Two of the three internal amino acid sequences shared homology with Coleopteran ?-glucosidases. In addition, the fraction containing the Cry8Da toxin binding protein had ?-glucosidase activity but no aminopeptidase N and alkaline phosphatase activity, both of which are commonly reported as receptors for Cry toxins in Lepidopteran and Dipteran insects. The ?-glucosidase homologous genes could be amplified by PCR using degenerate oligonucleotide primers designed from a conserved sequence of Coleopteran ?-glucosidases and an internal amino acid sequence of the Cry8Da toxin binding protein. Taken together, the ?-glucosidase in adult P. japonica BBMV is the receptor for B. thuringiensis Cry8Da toxin. PMID:23541518

  13. Selective increase of in vivo firing frequencies in DA SN neurons after proteasome inhibition in the ventral midbrain.

    PubMed

    Subramaniam, Mahalakshmi; Kern, Beatrice; Vogel, Simone; Klose, Verena; Schneider, Gaby; Roeper, Jochen

    2014-09-01

    The impairment of protein degradation via the ubiquitin-proteasome system (UPS) is present in sporadic Parkinson's disease (PD), and might play a key role in selective degeneration of vulnerable dopamine (DA) neurons in the substantia nigra pars compacta (SN). Further evidence for a causal role of dysfunctional UPS in familial PD comes from mutations in parkin, which results in a loss of function of an E3-ubiquitin-ligase. In a mouse model, genetic inactivation of an essential component of the 26S proteasome lead to widespread neuronal degeneration including DA midbrain neurons and the formation of alpha-synuclein-positive inclusion bodies, another hallmark of PD. Studies using pharmacological UPS inhibition in vivo had more mixed results, varying from extensive degeneration to no loss of DA SN neurons. However, it is currently unknown whether UPS impairment will affect the neurophysiological functions of DA midbrain neurons. To answer this question, we infused a selective proteasome inhibitor into the ventral midbrain in vivo and recorded single DA midbrain neurons 2 weeks after the proteasome challenge. We found a selective increase in the mean in vivo firing frequencies of identified DA SN neurons in anesthetized mice, while those in the ventral tegmental area (VTA) were unaffected. Our results demonstrate that a single-hit UPS inhibition is sufficient to induce a stable and selective hyperexcitability phenotype in surviving DA SN neurons in vivo. This might imply that UPS dysfunction sensitizes DA SN neurons by enhancing 'stressful pacemaking'. PMID:25059097

  14. Identification of circulating antibodies in fasciolosis and localization of 66 kDa antigenic target using monoclonal antibodies.

    PubMed

    Krailas, D; Viyanant, V; Ardseungnoen, P; Sobhon, P; Upatham, E S; Keawjam, R

    1999-03-01

    We identified three specific circulating antibodies in serum of cattle naturally infected with Fasciola gigantica. Two of the antibodies were found to react specifically to 97 and 66 kDa antigenic molecules of adult worm tegumental membrane extract. The third antibody was identified by the reaction with 26-28 kDa molecule of the excretory/secretory antigens. Monoclonal antibody against 66 kDa protein was developed and used for localization of its antigenic target in adult worm frozen sections. The experiment demonstrated that 66 kDa protein is a component on the outer surface membrane and on the membrane lining of the caecal epithelial of adult worm. The 66 kDa antigen was considered as a promising candidate for immunodiagnosis and vaccine. PMID:10403009

  15. Universidade Federal de Santa Catarina-Campus Joinville Centro de Engenharia da Mobilidade

    E-print Network

    Floeter, Sergio Ricardo

    Mobilidade www.petemb.ufsc.br BoletimInformativo Editorial Com o objetivo de divulgar notícias e informações e, a própria Engenharia da Mobilidade estamos dando continuidade ao Boletim Informativo do PET. O Babitonga no Desafio Solar Brasil 2012 ­ Etapa Florianópolis Texto elaborado por Evandro Machado ­ Líder

  16. L'OCCULTAMENTO DELLE VIOLENZE SUI MINORI: IL CASO DELLA SINDROME DA ALIENAZIONE PARENTALE

    Microsoft Academic Search

    MICAELA CRISMA; PATRIZIA ROMITO

    In letteratura e nei tribunali italiani si sente parlare sempre più spesso della Sindrome da Alienazione Parentale (SAP) per spiegare il fatto che in taluni casi, dopo una separazione, la madre, solitamente il genitore affidata- rio, si opponga a mandare i figli in visita al padre arrivando a denunciarlo per abuso sessuale. Queste denunce sarebbero sempre false, anche quando i

  17. Revista da Biologia www.ib.usp.br/revista ISSN 1984-5154 Sumrio _____________________________ Volume 5

    E-print Network

    Morandini, Andre C.

    Viegas Rodrigues #12;Revista da Biologia ­ www.ib.usp.br/revista Expediente ____________________________________ Editor Executivo: Welington Braz Carvalho Delitti Coordenação: Agustín Camacho Guerrero Pedro Ribeiro Cheixas-Dias Carlos Eduardo Amancio Daiane Gil Franco Danilo Flores Evelyn Loures de Godoi Gustavo Requena

  18. O orçamento público: algumas considerações conceituais e suas implicações para o financiamento da educação

    Microsoft Academic Search

    Maria Dilnéia Espíndola Fernandes

    1. O planejamento: elemento sintetizador de uma concepção de Estado. O propósito deste trabalho é traçar aproximações entre os conceitos que norteiam a legislação orçamentária vigente no Brasil e, até que ponto, através da execução dos orçamentos, tais conceitos são observados dando consistência e transparência tanto em uma concepção de, quanto na operacionalização das finanças públicas. Neste sentido vale o

  19. Relatrio Final de TFC Desenvolvimento Automtico de Sistemas 02-04-2013 N. da Proposta: 12

    E-print Network

    da Silva, Alberto Rodrigues

    que seria desejável. Neste TFC, foi proposta uma solução: uma conversão da plataforma Eclipse (disponível em Java) para .NET. Esta plataforma oferece um mecanismo de extensibilidade poderoso, mas incentiva ao mesmo tempo a modularidade e ao encapsulamento. A plataforma foi convertida, adaptada para

  20. A Proof Markup Language for Semantic Web Paulo Pinheiro da Silva Deborah L. McGuinness

    E-print Network

    da Silva, Paulo Pinheiro

    A Proof Markup Language for Semantic Web Services Paulo Pinheiro da Silva Deborah L. Mc,dlm,fikes}@ksl.stanford.edu Abstract The Semantic Web is being designed to enable automated reasoners to be used as core components), an interlingua representation for justifications of results produced by Semantic Web ser- vices. We also

  1. 1-D Signal Prediction Using Wavelets. S.A. Karkanis1, D.A. Karras2

    E-print Network

    Athens, University of

    1-D Signal Prediction Using Wavelets. S.A. Karkanis1, D.A. Karras2 and B.G. Mertzios3 1NCSR signal prediction performance of MultiLayer Perceptrons (MLPs) by incorporating wavelet based features and Vaidyanathan bases are compared, when these MLPs are applied to 1-D irregular signals. It is shown that

  2. 2012. D.A. Menasce. All Rights Reserved. On the Use of Performance

    E-print Network

    Menascé, Daniel A.

    neurons that run between the central nervous system and various internal organs such as the: heart, lungs in the human autonomic nervous system: ­ "The autonomic nervous system consists of sensory neurons and motorPages/P/PNS.html ­ The autonomic nervous system functions in an involuntary, reflexive manner. © 2012 D.A. Menasce. All Rights

  3. CARACTERIZAÇÃO DA ATIVIDADE FÍSICA HABITUAL EM ADOLESCENTES DE AMBOS OS SEXOS ATRAVÉS DE ACELEROMETRIA E PEDOMETRIA

    Microsoft Academic Search

    Vítor Pires LOPES; José António; Ribeiro MAIA; Maria Madalena de Castro OLIVEIRA; André SEABRA; Rui GARGANTA

    RESUMO Os propósitos desta pesquisa foram os s eguintes: a) estudar o perfil de a tividade física de adolescentes de ambos os sexos ao longo de cinco dias consecutivos, incluíndo o fim-de-semana, analisando a variabilidade interindividual e as diferenças entre os s exos; b) estudar a c omunalidade e o caráter único da informação fornecida pela ace lerometria e pedometria.

  4. Interdisciplinary Collaborative Research Grant Program Terms Revised: DA 11-28-12 Page 1

    E-print Network

    Michelson, David G.

    Interdisciplinary Collaborative Research Grant Program Terms Revised: DA 11-28-12 Page 1 Office of Research Services Phone: (250) 807 9412 UBC Okanagan Campus Internal Grants Program Terms INTERDISCIPLINARY COLLABORATIVE RESEARCH GRANT Value: Minimum - $3,000; Maximum - $15,000 Application Deadline Competition Results

  5. Individual Research Grant Program Terms Revised: DA 11-28-12 Page 1

    E-print Network

    Michelson, David G.

    Individual Research Grant Program Terms Revised: DA 11-28-12 Page 1 Office of Research Services Phone: (250) 807 9412 UBC Okanagan Campus Internal Grants Program Terms INDIVIDUAL RESEARCH GRANT Value Individual Research Grant is to provide awards of up to $5,000 to enable faculty to investigate a new idea

  6. Internal Research Grant Checklist Faculty Revised: DA 01-14-13

    E-print Network

    Michelson, David G.

    Internal Research Grant ­ Checklist ­ Faculty Revised: DA 01-14-13 Office of Research Services Phone: 250 807 9412 InternalResearchGrant FACULTYCHECKLIST (to accompany your grant application) This application is a: Individual Research Grant Interdisciplinary Collaborative Research Grant Faculty Travel

  7. Ris-R-1297 (DA) Fordelingsvirkninger af energi-og miljaf-

    E-print Network

    Management Services Denmark A/S, 2001. #12;Indhold 1 Miljø- og energiafgifter i Danmark 5 1.1 Hvilke the indirect tax effect from environmental taxes imposed on domestic production of goods and services Risø-R-1297 (DA) ISBN: 87-550-2956-6 ISBN: 87-550-2957-4 (Internet) ISSN: 0106-2840 Print: Pitney Bowes

  8. Upstream urbanization exacerbates urban heat island effects Da-Lin Zhang,1

    E-print Network

    Zhang, Da-Lin

    Upstream urbanization exacerbates urban heat island effects Da-Lin Zhang,1 Yi-Xuan Shou,1; published 19 December 2009. [1] Urban Heat Island (UHI) effects adversely impact weather, air quality urbanization exacerbates urban heat island effects, Geophys. Res. Lett., 36, L24401, doi:10.1029/2009GL041082

  9. Em busca da caixa mágica: o Estado Novo e a televisão

    Microsoft Academic Search

    Áureo Busetto

    2007-01-01

    RESUMO A análise histórica sobre a Exposição de Televisão (Rio de Janeiro, 1939), evento promovido pelo Estado Novo em parce- ria com o Terceiro Reich alemão, permi- te trazer, além de dados sobre a história da TV no Brasil, elementos de compreen- são sobre as primeiras relações entre po- der político e esse meio de comunicação no país. Pois, a

  10. PHOTOSYSTEM 11-ASSOCIATED PROTEIN KINASE PHOSPHORYLATES A NOVEL 6.3 kDa PROTEIN WHICH

    E-print Network

    Allen, John F.

    PHOTOSYSTEM 11-ASSOCIATED PROTEIN KINASE PHOSPHORYLATES A NOVEL 6.3 kDa PROTEIN WHICH SUBSEQUENTLY Laboratory, Upton, NY 11973, USA. Key words: auxiliary enzymes, kinases, protein-protein interactions presence of multiple protein kinases in this system is mounting. Phosphorylation appears to be redox

  11. ENCONTROS E ACORDOS INTERNACIONAIS: IMPLICAÇÕES NA PRÁTICA DA RESPONSABILIDADE SOCIAL EMPRESARIAL E GESTÃO AMBIENTAL

    Microsoft Academic Search

    Lucicleide de Souza Barcelar

    2010-01-01

    Este estudo busca fazer uma reflexão dos principais encontros internacionais no tocante do desenvolvimento sustentável e os acordos internacionais, os quais incidem nas diretrizes da responsabilidade social empresarial e gestão ambiental. Em um mundo globalizado e cada vez mais competitivo, há uma crescente exigência as empresas, assim como restrições dos mercados, que impõe uma série de leis, normas e acordos

  12. RESPONSABILIDADE SOCIAL NO AGRONEGÓCIO COOPERATIVO: O CASO DA COOPERATIVA AGRÍCOLA CONSOLATA

    Microsoft Academic Search

    Karina Sayuri Nishigawa; Fatima Pegorini Gimenes; Regio Marcio Toesca Gimenes

    2008-01-01

    A destruição do meio ambiente, o desemprego e a negligência para com a sociedade fizeram com que o mundo empresarial passasse a encarar a responsabilidade social como uma nova estratégia para potencializar seu desenvolvimento a longo prazo. Neste sentido, os princípios cooperativistas abrangidos por adesão livre; distribuição das sobras líquidas; gestão democrática; promoção da educação; taxa limitada de juros ao

  13. Localization of a 170 kDa myosin heavy chain in plant cells

    Microsoft Academic Search

    E. Yokota; A. R. McDonald; B. Liu; T. Shimmen; B. A. Palevitz

    1995-01-01

    Summary A polyclonal antibody directed against a 170 kDa myosin heavy chain from lily pollen tubes was employed to (a) assess the cellular distribution of the polypeptide using immunofluorescence methods, and (b) ascertain if similar polypeptides are present in pollen tubes and somatic cells of other species. Fluorescence is associated with particles of various size as well as an amorphous

  14. Estudo comparativo das amplitudes de movimento da coluna cervical em idosos com diferentes níveis de aptidão

    Microsoft Academic Search

    Cristiano Oliveira de Carvalho; Denis Aron; José Alberto; Alves Silva; Luis Flávio Horta Bicalho; Ana Paula; Leonardo Oliveira Pena Costa; Vânia Ferreira de Figueiredo

    2006-01-01

    REsumo Introdução:Este estudo tem como objetivo analisar e comparar as amplitudes de movimento (ADM) da coluna cervical em dois grupos de idosos com níveis diferentes de aptidão física. Métodos: Foram selecionados 40 voluntários assintomáticos com idade entre 60-75 anos e subdivididos pelo seu respectivo nível de aptidão física. Os voluntários então foram submetidos a mensuração de suas respectivas ADM pelo

  15. Avaliação de compostos com atividade antioxidante em células da levedura Saccharomyces cerevisiae

    Microsoft Academic Search

    Daniele Grazziotin Soares; Ana Cristina Andreazza; Mirian Salvador

    2005-01-01

    Antioxidantes são compostos que atuam inibindo e\\/ou diminuindo os efeitos desencadeados pelos radicais livres e compostos oxidantes. Diferentes métodos têm sido desenvolvidos para obter a diferenciação, seja qualitativa ou quantitativa, da capacidade antioxidante de compostos, tanto através de testes sem a utilização de células (testes químicos) ou utilizando culturas celulares (testes biológicos). Os testes químicos são mais rápidos e simples

  16. Design of 3G net monitor system based on DaVinci technology

    Microsoft Academic Search

    Liu Ronglin; Cheng Xiaodong

    2010-01-01

    Outdoor remote surveillance is very difficult, and the wireless video surveillance needs high real time, but has large amount of computation and the limited available bandwidth. In order to solve the above problems proposed the 3G net monitor system solutions based on DaVinci technology. The program needs low cost, has superior performance and can be work outdoor. In the field

  17. MULTIPLY MODAL EXTENSIONS OF DA COSTA'S Cn, 1 n !, LOGICAL RELATIVISM, AND THE IMAGINARY

    Microsoft Academic Search

    GERT-JAN C. LOKHORST

    How should our logic express what other logics deem necessary? How should we give a rational account of forms of rationality which are dier- ent from ours? The present paper answers these questions. It shows how to enrich logical systems with operators which describe what is necessary, rational and imaginary according to other systems. Although only da Costa's paracon- sistent

  18. FromDaDy: Spreading Aircraft Trajectories Across Views to Support Iterative Queries

    E-print Network

    Paris-Sud XI, Université de

    FromDaDy: Spreading Aircraft Trajectories Across Views to Support Iterative Queries Christophe Hurter, Benjamin Tissoires, and Stéphane Conversy Abstract--When displaying thousands of aircraft of managing airspace requires trajectories analysis. An aircraft trajectory is a record of positions

  19. 32 CFR 644.512 - DA-SBA joint set-aside determination.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal Disposal of Standing Timber, Crops, and Embedded Gravel, Sand and Stone § 644.512 DA-SBA joint set-aside determination. Section 15 of the Small Business Act (15 U.S.C....

  20. 32 CFR 644.512 - DA-SBA joint set-aside determination.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal Disposal of Standing Timber, Crops, and Embedded Gravel, Sand and Stone § 644.512 DA-SBA joint set-aside determination. Section 15 of the Small Business Act (15 U.S.C....

  1. 32 CFR 644.512 - DA-SBA joint set-aside determination.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal Disposal of Standing Timber, Crops, and Embedded Gravel, Sand and Stone § 644.512 DA-SBA joint set-aside determination. Section 15 of the Small Business Act (15 U.S.C....

  2. 32 CFR 644.512 - DA-SBA joint set-aside determination.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal Disposal of Standing Timber, Crops, and Embedded Gravel, Sand and Stone § 644.512 DA-SBA joint set-aside determination. Section 15 of the Small Business Act (15 U.S.C....

  3. GLOBULAR CLUSTERS AROUND GALAXIES IN GROUPS Cristiano Da Rocha and Claudia Mendes de Oliveira

    E-print Network

    Puzia, Thomas H.

    GLOBULAR CLUSTERS AROUND GALAXIES IN GROUPS Cristiano Da Rocha and Claudia Mendes de Oliveira proposed to be a merger remnant. Our analysis of B and R images uncovered a population of globular clusters and SN = 1.8 Æ 1.1 (0.8 Æ 0.4) for NGC 6868. The radial profile of the globular clusters of NGC 1199

  4. Aspectos ideativos no transtorno da compulsão alimentar periódica: estudo com o Rorschach

    Microsoft Academic Search

    Teresa Cristina; Bailoni Martins Passos; Latife Yazigi; Angélica Medeiros Claudino

    Resumo Pessoas com diagnóstico de transtorno da compulsão alimentar periódica (DSM-IV) são descritas como propensas a distúrbios nos processos de pensamento que são relevantes para a manutenção do quadro e para o tratamento. Este é um estudo exploratório visando avaliar o funcionamento cognitivo de sujeitos com o diagnóstico citado, sendo escolhido como instrumento o método de Rorschach, que permite acessar

  5. Two rubber balloons: Phase diagram of air transfer Yan Levin* and Fernando L. da Silveira

    E-print Network

    Levin, Yan

    Two rubber balloons: Phase diagram of air transfer Yan Levin* and Fernando L. da Silveira Instituto that depending on initial balloon volumes, when the valve is opened the air will flow either from the larger with air and connected by a hose with a valve. For simplicity, we shall approximate the balloons by spheres

  6. Uniform remote control of front end processors in PAN-DA

    SciTech Connect

    Berg, D.; Berman, E.; MacKinnon, B.; Nicinski, T.; Oleynik, G.; Petravick, D.; Pordes, R.; Sergey, G.; Slimmer, D.; Streets, J.; White, V.

    1991-06-01

    The PAN-DA data acquisition software system encompasses support for a variety of front end processors including the Struck General Purpose Master (GPM), the Fermilab Smart Crate Controller (FSCC), and the Motorola MVME133-A VME single board computer. PAN-DA provides support for the remote control of these processors through its Remote Procedure eXecution (RPX) software. This software runs over serial lines, and in some PAN-DA environments, over the Ethernet and TCP/IP as well. Experiments E791 and E771 have successfully used RPX software in both FSCC software development and data collection during the 1990--1991 fixed target run at Fermilab. RPX software has facilitated development and testing of the Fermilab Silicon Strip Detector readout system, for which the FSCC is an integral component. RPX based control and monitoring of the GPM and the MVME133-A are essential parts of the PAN-DA data acquisition system used by E687 and E773 during the 1990--1991 run. 6 refs., 2 figs.

  7. The Validity of the Autism Spectrum Disorders-Diagnosis for Intellectually Disabled Adults (ASD-DA)

    ERIC Educational Resources Information Center

    Matson, Johnny L.; Wilkins, Jonathan; Boisjoli, Jessica A.; Smith, Kimberly R.

    2008-01-01

    Psychologists interviewed direct-care staff using a battery of assessment measures including the autism spectrum disorders-diagnosis for intellectually disabled adults (ASD-DA), the Diagnostic Assessment for the Severely Handicapped-II (DASH-II), the Matson Evaluation of Social Skills for Individuals with Severe Retardation (MESSIER), the…

  8. VIII Simpsio de Pesquisa Operacional e Logstica da Marinha 16 a 17 de agosto de 2005

    E-print Network

    Cruz, Frederico

    modelos é o decrescimento da taxa de serviço com o aumento do número de usuários no sistema, conforme Sistemas modelados por redes de filas finitas configuradas em redes vêm atraindo a atenção de muitos analiticamente, mas alguns sistemas de interesse, em arranjos mais complexos, ainda resistem ao tratamento

  9. Anlise da Aplicabilidade dos Modelos de Argumentao na Resoluo Alternativa de

    E-print Network

    Antunes, Pedro

    Análise da Aplicabilidade dos Modelos de Argumentação na Resolução Alternativa de Conflitos Sara, Departamento de sistemas e Informática, Campus do IPS-Estefanilha, 2910-761 Setúbal, Setúbal, Portugal 2 destaque no contexto do actual sistema judicial. Este trabalho aborda a resolução alternativa de conflitos

  10. 272 201 4 /2015 C A L E N DA R Instructor and Co-developer,

    E-print Network

    Sokolowski, Marla

    Distance & Online Learning Access more expertise. Distance and Online Learning at the School helps helps DA R Distance & Online Learning Contents 275 Distance Learning: Q & A 276 Arts & Science 276 Health Process Management 276 Business Strategy 277 E-Learning 277 Human Resources 277 Information Technology

  11. Endogeneity Bias May be Contagious DA Freedman Statistics 215 November 2007

    E-print Network

    Sekhon, Jasjeet S.

    Endogeneity Bias May be Contagious DA Freedman Statistics 215 November 2007 1) Let x and w be fixed n-vectors with mean 0. Let (i, i) be IID pairs of normal random variables, with expectation 0 biased downward by rc2 1 + 2 - r2 . (f) Show that endogeneity bias affects ^a unless r = 0. (g) Can

  12. Padrão da prescrição de atividade física realizada por médicos ortopedistas brasileiros

    Microsoft Academic Search

    Alexandre Mader Seixas; Sandra M. M. Matsudo; Victor K. R. Matsudo; Erinaldo L. Andrade; Glaucia F. Braggion

    Objetivo: avaliar a prescrição de atividade física realizada por ortopedistas brasileiros. Metodologia: 521 ortopedistas responderam um questionário sobre prescrição de atividade física. Os parâmetros prescritos de freqüência, duração e intensidade considerados corretos foram: realizar pelo menos 30 minutos contínuos ou acumulados de atividade moderada na maioria dos dias da semana. Utilizada análise estatística descritiva. Resultados: 86,4% prescrevem atividade física para

  13. Migration from can coatings: Part 2. Identification and quantification of migrating cyclic oligoesters below 1000?Da

    Microsoft Academic Search

    A. Schaefer; V. A. Ohm; T. J. Simat

    2004-01-01

    Metal cans for food use can be coated with lacquers based on polyester resins. Recent research has focussed on the identification and quantification of migrants released by coatings that are potentially absorbable (below 1000?Da). The presented method describes a procedure that was optimized to hydrolyse the polyester migrants into their monomers, polyvalent acids and polyols. The polyols were identified by

  14. Specific binding of victorin to a 100-kDa protein from oats

    SciTech Connect

    Wolpert, T.J.; Macko, V. (Cornell Univ., Ithaca, NY (USA))

    1989-06-01

    Susceptibility of oats to victoria blight, caused by the fungus Cochliobolus victoriae, and sensitivity to the host-specific toxin victorin, produced by the fungus, are controlled by the dominant allele at the Vb locus. It has been postulated that the Vb locus encodes a toxin receptor, although direct evidence for such a receptor is not available. Recent studies on structure-activity relationships of the toxin established a methodology for producing {sup 125}I-labeled victorin. Electrophoretic analysis of proteins from isogenic susceptible and resistant oat genotypes following treatment of leaves with radiolabeled victorin showed that victorin binds in a covalent and a genotype-specific manner to a 100-kDa protein only in susceptible oat leaf slices. This in vivo binding was competitively displaced by reduced victorin, a nontoxic protective compound, and appeared to be correlated with biological activity. In vitro binding to the 100-kDa protein in leaf extracts showed several differences from in vivo binding. Binding was not genotype specific and required a reducing agent that was not required for in vivo binding. Differential centrifugation showed that the 100-kDa victorin binding protein was not a cytosolic protein but was enriched in a high-speed particulate fraction. The data support the hypothesis that the 100-kDa protein is the victorin receptor.

  15. Understanding and Interpreting Japanese NP1 "wa" NP2 "da" Sentences: Mechanism and Contextual Factors

    ERIC Educational Resources Information Center

    Yoshida, Megumi

    2013-01-01

    This dissertation investigates the contextual factors that affect the understanding and interpretation of one Japanese topicalized construction, NP[subscript 1] wa NP[subscript 2] da sentences, by native speakers of Japanese. The construction allows two possibilities in the relation between the NP[subscript 1] and the NP[subscript 2]. When the two…

  16. Correlation of fretting fatigue experimental results using an asymptotic approach D.A. Hills a

    E-print Network

    Barber, James R.

    Correlation of fretting fatigue experimental results using an asymptotic approach D.A. Hills a , A online 23 February 2012 Keywords: Fretting fatigue Incomplete contacts Asymptotic methods Short crack. They are then used to re-analyse several sets of publicly available fretting fatigue data. Several different

  17. Original article Peripheral concentrations of a 60-kDa pregnancy

    E-print Network

    Paris-Sud XI, Université de

    Original article Peripheral concentrations of a 60-kDa pregnancy serum protein during gestation for studying pregnancy in cattle we examined the characteristics of a pregnancy serum protein produced = 26). From 27 d post-Al to the end of pregnancy the plasma PSP60 concentration increased, especially

  18. Análise da fadiga dos músculos paraespinhais em indivíduos saudáveis na posição sentada

    Microsoft Academic Search

    Marcio Massao Kawano; Ito Ramos de Oliveira; Marcela Carrilho Boer; Roger Burgo de Souza; Jefferson Rosa Cardoso

    Resumo - O objetivo deste estudo foi avaliar os parâmetros de freqüência e ampli- tude da eletromiografia de superfície durante a fadiga dos músculos paraespinhais em indivíduos saudáveis na posição sentada. Participaram do estudo 11 indivíduos do gênero masculino, saudáveis e livres de sintomas de dor lombar. Um eletromiógrafo de superfície foi utilizado para obtenção dos parâmetros eletromiográficos. Foram posicionados

  19. ORIGINAL ARTICLE Co-activation of VTA DA and GABA neurons mediates

    E-print Network

    Gutkin, Boris

    on nicotinic acetylcholine receptors (nAChRs), a heterogeneous family of pentameric, ligand-gated ion channelsORIGINAL ARTICLE Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement S Tolu1 acetylcholine receptor (nAChR), expressed on most neurons, and also many other organs in the body. Even within

  20. Determinação da massa de júpiter a partir das órbitas de seus satélites: um experimento didático

    NASA Astrophysics Data System (ADS)

    Schlickmann, M. S.; Saito, R. K.; Becker, D. A.; Rezende, M. F., Jr.; Cid Fernandes, R.

    2003-08-01

    Este trabalho apresenta o roteiro piloto de uma prática observacional em astronomia, junto com os primeiros resultados obtidos nesta fase de implementacão. O projeto, que será executado em duas etapas, visa introduzir noções de Astronomia a alunos do Ensino Médio e iniciantes nos cursos de Física. O experimento consiste em medir as órbitas dos satélites Galileanos e, a partir da análise dos dados coletados, verificar a validade da Lei das órbitas de Kepler, determinando a massa do planeta Júpiter. Em uma primeira etapa, as observações serão feitas utilizando um telescópio Meade LX200 10" e câmera CCD para obter uma seqüência de imagens do planeta, que possibilitará medir o movimento de seus satélites. A segunda etapa terá início a partir do funcionamento do telescópio em modo robótico, com a possibilidade de observações via internet por instituições de ensino. Para o desenvolvimento deste experimento foram inicialmente coletadas várias imagens de Júpiter obtidas com os instrumentos citados acima. Estas imagens serviram como base para confecção dos roteiros para a experiência no nível médio e superior. Os roteiros serão inicialmente apresentados em uma home-page. Nela também se buscará uma contextualização histórica da experiência bem como o estabelecimento de relações com professores e alunos, propostas metodológicas e a disponibilização dos programas computacionais necessários para a utilização "on-line" pelos usuários. O projeto conta com apoio da Fundação VITAE.

  1. A Integracao de Ensino das Ciencias da Saude (An Integrated Medical Education Program [in Brazil]).

    ERIC Educational Resources Information Center

    Pourchet-Campos, M. A.; Guimaraes Junior, Paulino

    At the Sixth Annual Reunion of the Brazilian Association of Medical Schools (VI Reuniao Anual da Associacao Brasileira de Escolas Medicas) leaders in the Brazilian medical profession proposed an integrated educational program for training students in the fields of medicine and public health. Under Brazil's present system of education, all…

  2. The bow shocks and upstream waves of Venus and Mars D.A. Brain *

    E-print Network

    California at Berkeley, University of

    The bow shocks and upstream waves of Venus and Mars D.A. Brain * LASP/University of Colorado; accepted 14 May 2003 Abstract Because they both lack measurable magnetic fields, Venus and Mars are often waves are observed. In many respects the collisionless shocks at Venus and Mars are quite different

  3. Programao da Semana do Calouro do Curso de Terapia Ocupacional Professora Regina C. T. Castanharo

    E-print Network

    Paraná, Universidade Federal do

    Programação da Semana do Calouro do Curso de Terapia Ocupacional Professora Regina C. T. Castanharo Coordenadora do Curso de Terapia Ocupacional SEGUNDA ­ FEIRA 03/02 TERÇA- FEIRA 04/02 QUARTA ­ FEIRA 05 dos calouros pela Coordenação- Apresentação do curso Explicar sobre o que é o trote Explicar sobre o

  4. Long-term evolution of 1991 DA: A dynamically evolved extinct Halley-type comet

    NASA Technical Reports Server (NTRS)

    Hahn, Gerhard; Bailey, M. E.

    1992-01-01

    The long-term dynamical evolution of 21 variational orbits for the intermediate-period asteroid 1991 DA was followed for up to +/-10(exp 5) years from the present. 1991 DA is close to the 2:7 resonance with Jupiter; it has avoided close encounters, within 1 AU, with this planet for at least the past 30,000 years, even at the node crossing. The future evolution typically shows no close encounters with Jupiter within at least 50,000 years. This corresponds to the mean time between node crossings with either Jupiter or Saturn. Close encounters with Saturn and Jupiter lead to a chaotic evolution for the whole ensemble, while secular perturbations cause large-amplitude swings in eccentricity and inclination (the latter covering the range 15 deg approximately less than i approximately less than 85 deg) which correlate with deep excursions of the perihelion distance to values much less than 1 AU. These variations are similar to those found in P/Machholz and a variety of other high-inclination orbits, e.g., P/Hartley-IRAS. We emphasize the connection between the orbital evolution of 1991 DA and that of Halley-type comets. If 1991 DA was once a comet, it is not surprising that it is now extinct.

  5. CINÉTICA DE ABSORÇÃO DE NUTRIENTES POR ALFACE EM HIDROPONIA - NFT - COM DUAS CONCENTRAÇÕES DA SOLUÇÃO NUTRITIVA

    Microsoft Academic Search

    G. C. S. Matias; N. N. Cometti; M. S. Fernandes

    A absorção de nutrientes pelas plantas pode ser descrita por parâmetros cinéticos: Vmax (máxima velocidade de absorção do nutriente por unidade de raiz), Km (concentração externa na qual a velocidade de absorção é a metade da máxima) e Cmin (concentração externa na qual o fluxo líquido de íons é zero). O uso de parâmetros cinéticos pode auxiliar tanto na seleção

  6. 76 FR 31457 - Airworthiness Directives; Diamond Aircraft Industries GmbH Model DA 42 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-01

    ...2120-AA64 Airworthiness Directives; Diamond Aircraft Industries GmbH Model DA 42 Airplanes...information identified in this AD, contact Diamond Aircraft Industries GmbH, N.A. Otto-Stra...43 2622 26780; e- mail: office@diamond-air.at; Internet:...

  7. 76 FR 14346 - Airworthiness Directives; Diamond Aircraft Industries GmbH Model DA 42 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ...2120-AA64 Airworthiness Directives; Diamond Aircraft Industries GmbH Model DA 42 Airplanes...identified in this proposed AD, contact Diamond Aircraft Industries GmbH, N.A. Otto-Stra...43 2622 26780; e-mail: office@diamond-air.at; Internet:...

  8. Trusting Answers on the Web Deborah L. McGuinness and Paulo Pinheiro da Silva

    E-print Network

    da Silva, Paulo Pinheiro

    Trusting Answers on the Web Deborah L. McGuinness and Paulo Pinheiro da Silva Knowledge Systems applications return answers, many users do not know what information sources were used, when they were updated support for explaining reasoning paths used to de- rive or retrieve answers. The Inference Web (IW) aims

  9. Assessments of the economic impacts of natural hazards in Albania: application of DaLA methodology.

    NASA Astrophysics Data System (ADS)

    Massabo, Marco; Toto, Emanuela; Deda, Miranda; Prenci, Shemsi; Dhima, Maksimiljan

    2015-04-01

    Disaster loss datasets are built using economic assessments done by different parties and using different approaches which are in many cases inconsistent. This is observed in more than 75% of the Alabanian records with missing economic evaluations. To assess the economic impact of disasters at all scales in Global Assessment Report on Disaster Risk Reduction 2011 and 2013 has used the DaLA methodology that takes advantage of a common and homogeneous set of quantitative physical damage indicators contained in the disaster databases. These have to be taken as the lower bound of the damage, which in general is higher. The UN-ECLAC DaLA Methodology takes into account in its assessments the overall status of economy of the affected country. It uses the national accounts and statistics of the country government as baseline data to assess damage and loss. It also factors in the impact of disasters on individual livelihoods and incomes to fully define the needs for recovery and reconstruction. Similarly to national disaster loss databases DaLA assessments have a national level of observation and data produced at sub-national resolution, resulting in highly detailed and accurate data sets. In 2013 in Albania was implemented a collection of disaster losses based on Desinventar. We applied the DaLa methodology to the Albanian database of impacts of natural disasters.

  10. SYMPLECTIC ORIGAMI A. CANNAS DA SILVA, V. GUILLEMIN, AND A. R. PIRES

    E-print Network

    Cannas da Silva, Ana

    SYMPLECTIC ORIGAMI A. CANNAS DA SILVA, V. GUILLEMIN, AND A. R. PIRES Abstract. An origami manifold a compact base. We can move back and forth between origami and symplectic mani- folds using cutting (unfolding) and radial blow-up (folding), mod- ulo compatibility conditions. We prove an origami convexity

  11. Dept. Computaci'on. Universidade da Coru~na Apellidos: Nombre: DNI

    E-print Network

    Barreiro, Alvaro

    las hojas antes de entregar incluida la hoja de enunciados ­Tiempo: 2h. 30m. 1. Da una breve definici cognitiva (4 puntos) (a) introspecci'on psicol'ogica (b) dualismo de sustancia (c) funcionalismo de m'aquina.5 puntos) 5. ?Son los modelos mentales de razonamiento de Johnson­Laird capaces de explicar al mismo tiempo

  12. DiagnÛstico e tratamento da hepatite B Diagnosis and treatment of hepatitis B

    Microsoft Academic Search

    Marcelo Simão Ferreira

    Resumo A hepatite B constitui grave problema de saúde pública. Estima-se que 350 milhões de pessoas, ou seja, 5% da população mundial sejam portadores dessa virose. Admite-se que a infecção evolui para a cura em 90% a 95% dos casos e para o estado de portador crônico nos restantes 5% a 10%; a infecção persistente pode resultar também em cirrose,

  13. Validation of the Delvotest SP NT DA. Performance Tested Method 011101.

    PubMed

    Hennart, Stephen L A; Faragher, John

    2012-01-01

    Delvotest SP NT DA is designed to test milk for the presence of antibacterial substances, such as antibiotics. The test is made of an agar gel containing bacterial spores and a color indicator. The milk sample is added onto the agar gel, and the test is incubated at 64 degrees C. The principle of the test is based on the diffusion of possible inhibitory substances that may be present in the milk sample into agar. This reduces growth and acid production by the test organism, and delays or prevents the agar from changing color from purple to yellow. The Delvotest Accelerator is an automated system in which the plates containing the milk to be analyzed are placed for incubation. The Accelerator automatically detects the end of the incubation and reads the results. A sample containing antibiotic will be noted as "positive." A sample without antibiotics or with antibiotics at concentrations below detection level will be noted as "negative." The present report includes all technical details about the Delvotest SP NT DA, and the results of the validation study. The validation study demonstrates that the Delvotest SP NT DA conforms to the product performance claims and confirms the robustness of the test. The Delvotest SP NT DA is, therefore, granted Performance Tested Method certification. PMID:22468368

  14. Instrument Failures for the da Vinci Surgical System: a Food and Drug Administration MAUDE Database Study

    E-print Network

    Background Our goal was to analyze reported instances of the da Vinci robotic surgical system instrument of the robotic technology. Methods We conducted a survey of the MAUDE data- base and tallied robotic instrument groups (cautery, shaft, wrist or tool tip, cable, and control housing) based on technical differences

  15. A linguística e o consumidor: teoria, política e política da teoria

    Microsoft Academic Search

    Carlos A. M. Gouveia

    2006-01-01

    realidade social é constituída tanto por estruturas sociais abstractas como ,por eventos sociais concretos e que a relação entre umas e outros é mediada por práticas sociais, isto é,por formas de actividade social mais ou menos estáveis e permanentes, que concorrem para a constituição de áreas, instituições e organizações sociais (vd. Fairclough, 2005: 77), procurarei ao longo da comunicação analisar

  16. PROJETO GERES \\/ 2005: NOVOS INDICADORES PARA CONSTRUÇÃO E INTERPRETAÇÃO DA ESCALA DE PROFICIÊNCIA

    Microsoft Academic Search

    Lina Kátia; Mesquita de Oliveira; Creso Franco; Tufi Machado Soares

    2007-01-01

    1. INTRODUÇÃO Usualmente, programas de avaliação em larga escala utilizam uma metodologia de interpretação e construção de escalas de proficiência baseada na Teoria da Resposta ao Item e na análise pedagógica das habilidades avaliadas por meio de itens âncora, selecionados com base na freqüência observada de acertos. Dessa abordagem resultam escalas que associam a cada nível de proficiência um conjunto

  17. User Interface Modelling with UML Paulo Pinheiro da Silva and Norman W. Paton

    E-print Network

    da Silva, Paulo Pinheiro

    User Interface Modelling with UML Paulo Pinheiro da Silva and Norman W. Paton Department,norm}@cs.man.ac.uk Abstract. The Unified Modeling Language (UML) is a natural candi­ date for user interface (UI) modelling, it is by no means clear how to model UIs using UML. This paper presents a user inter­ face modelling case study

  18. User Interface Modelling with UML Paulo Pinheiro da Silva and Norman W. Paton

    E-print Network

    Pinheiro da Silva, Paulo

    User Interface Modelling with UML Paulo Pinheiro da Silva and Norman W. Paton Department,norm}@cs.man.ac.uk Abstract. The Unified Modeling Language (UML) is a natural candi- date for user interface (UI) modelling, it is by no means clear how to model UIs using UML. This paper presents a user inter- face modelling case study

  19. SPI methodology for Virtual Organizations Paula Ventura Martins1, Alberto Rodrigues da Silva 2

    E-print Network

    da Silva, Alberto Rodrigues

    SPI methodology for Virtual Organizations Paula Ventura Martins1, Alberto Rodrigues da Silva 2 1 the process and the project, new software process improvement (SPI) approaches have to consider process and project alignment and iterative SPI performed by project #12;teams. Currently, there seems to be a lack

  20. AVALIAÇÃO DA EFICÁCIA DE PROGRAMA DE FORMAÇÃO DE EMPREENDEDORES E LIDERANÇAS RURAIS NO ESTADO DO PARANÁ

    Microsoft Academic Search

    Vania Di Addario Guimaraes; Fernando Curi Peres; Luis Alberto Ambrosio; Jose Roberto Fernandes Canziani

    2008-01-01

    Este artigo apresenta os resultados de avaliações da eficácia do Programa Empreendedor Rural – PER – em alcançar seus objetivos. O PER é um programa de educação rural para produtores e trabalhadores rurais desenvolvido no Paraná e executado pelo Senar\\/PR e Sebrae\\/PR que visa elevar os estoques de capital humano e social no meio rural. O programa adota o construtivismo

  1. DaVis: A tool for Visualizing Data Quality Rajmonda Sulo* Stephen Eick

    E-print Network

    Grossman, Robert

    Vis uses a tabular reduced visual representation to show a dataset, highlights inaccuracies and invalid data, and shows difference between versions of a dataset. Our experience in using DaVis on several · timeliness · accessibility and · interpretability The accuracy of a dataset is the degree to which

  2. 27 kDa Fasciola gigantica glycoprotein for the diagnosis of prepatent fasciolosis in cattle.

    PubMed

    Ghosh, S; Rawat, Preeti; Velusamy, R; Joseph, David; Gupta, S C; Singh, B P

    2005-02-01

    An indirect enzyme-linked immunosorbent assay (ELISA) using 27 kDa glycoprotein of Fasciola gigantica has been evaluated for its potential use in the diagnosis of bovine fasciolosis. Following experimental infection of rabbits, F. gigantica infection-induced antibodies were isolated and later used as ligands in affinity chromatography for isolation of infection-induced antibody-specific proteins. Among the five infection-specific proteins isolated, a glycoprotein of 27 kDa was later isolated by second-step purification using concanavalin A matrix. In crossbred cattle receiving different doses of infection (100, 200 and 400 metacercariae), the anti-27 kDa antibodies were detected as early as the 2nd week post infection. No direct correlation between initial dose, antibody response and fluke establishment was recorded. No cross-reaction was noted with the sera of goats experimentally infected with Paramphistomum epiclitum. ELISA with the 27 kDa glycoprotein could be a feasible diagnostic tool for the early detection of bovine fasciolosis. PMID:15730136

  3. Energy Consumption Tools Pack Leandro Fontoura Cupertino, Georges DaCosta,

    E-print Network

    Lefèvre, Laurent

    Energy Consumption Tools Pack Leandro Fontoura Cupertino, Georges DaCosta, Amal Sayah, Jean Consumption Tools Pack 1 / 23 #12;Outline 1 Introduction Motivation Our proposal 2 Energy Consumption Tools Energy Consumption Library Data Acquisition Tool Data Monitoring Tool Energy Profiler 3 Conclusions

  4. Compositional Data Analysis (CoDA) Approaches to Distance in Information Retrieval

    E-print Network

    Thomas, Paul

    data by industry. In text processing, compo- sitional data can include genres, documents positive components that sum to the constant form the D-part simplex, denoted by SD [3]. From left. Geometrically, compositions are points on a D-part simplex (Figure 1). CoDA theory, as pioneered by Aitchison [1

  5. Low Energy Nuclear Reaction Research at the Naval Research Laboratory D.A. Kidwell1

    E-print Network

    Noble, James S.

    Low Energy Nuclear Reaction Research at the Naval Research Laboratory D.A. Kidwell1 , D have explored the field of Low Energy Nuclear Reactions (LENR) for about eight years focusing energy (as heat) is produced ­ neither nuclear products nor transmutations have been firmly established

  6. PanDA Beyond ATLAS : A Scalable Workload Management System For Data Intensive Science

    E-print Network

    Borodin, M; The ATLAS collaboration; Jha, S; Golubkov, D; Klimentov, A; Maeno, T; Nilsson, P; Oleynik, D; Panitkin, S; Petrosyan, A; Schovancova, J; Vaniachine, A; Wenaus, T

    2014-01-01

    The LHC experiments are today at the leading edge of large scale distributed data-intensive computational science. The LHC's ATLAS experiment processes data volumes which are particularly extreme, over 140 PB to date, distributed worldwide at over of 120 sites. An important element in the success of the exciting physics results from ATLAS is the highly scalable integrated workflow and dataflow management afforded by the PanDA workload management system, used for all the distributed computing needs of the experiment. The PanDA design is not experiment specific and PanDA is now being extended to support other data intensive scientific applications. PanDA was cited as an example of "a high performance, fault tolerant software for fast, scalable access to data repositories of many kinds" during the "Big Data Research and Development Initiative" announcement, a 200 million USD U.S. government investment in tools to handle huge volumes of digital data needed to spur science and engineering discoveries. In this talk...

  7. COMPORTAMENTO REPRODUTIVO DA ARARA-AZUL (Anodorhynchus hyacinthinus) NO PANTANAL, BRASIL

    Microsoft Academic Search

    Vanessa M. Bernardo; Marcos R. F. Cardoso; Carolina R. Pereira; Neiva M. R. Guedes

    Residente, monogâmica e altamente conspícua a arara-azul Anodorhynchus hyacinthinus é uma ave que pode servir de modelo para estudos de comportamento. De julho a dezembro de 1999, foram realizadas observações de comportamento reprodutivo da arara-azul no Pantanal de Miranda. Os estudos foram conduzidos no Refúgio Ecológico Caiman, onde desde 1998, esta situada a base do Projeto. O objetivo deste trabalho

  8. Totem e Tabu: Uma reflexão sobre o Complexo de Édipo na origem da civilização

    Microsoft Academic Search

    Josefa D. D. de Carvalho

    2002-01-01

    Resumo A decisão pela escolha deste tema, se deu a partir do interesse despertado nas apresentações e discussões em sala de aula sobre o texto Totem e Tabu. Para tanto, foi feito um recorte na teoria freudiana de um dos seus conceitos mais importante: o Complexo de Édipo. Este, segundo Freud, parece apontar para a possibilidade da sua existência na

  9. A Low Power Inverted Ladder D/A Converter Yevgeny Perelman and Ran Ginosar,

    E-print Network

    Ginosar, Ran

    1 A Low Power Inverted Ladder D/A Converter Yevgeny Perelman and Ran Ginosar, VLSI Systems Research/A converters typically use the fine, LSB ladder floating upon the static MSB ladder. The usage of the LSB ladder incurs a penalty in dynamic performance due to the added output resistance and switch matrix

  10. Studienordnung fr den Bachelor-Teilstudiengang Deutsch als Fremdsprache (DaF) an der

    E-print Network

    Greifswald, Ernst-Moritz-Arndt-Universität

    1 Studienordnung für den Bachelor-Teilstudiengang Deutsch als Fremdsprache (DaF) an der Ernst-Teilstudiengang Deutsch als Fremdsprache als Satzung: Inhaltsverzeichnis § 1 Geltungsbereich § 2 Studium § 3-Teilstudiengang Deutsch als Fremdsprache. Ergänzend gelten die Gemeinsame Prüfungsordnung für Bachelor- und

  11. Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography

    Microsoft Academic Search

    Kristina Lakomek; Achim Dickmanns; Matthias Kettwig; Henning Urlaub; Ralf Ficner; Torben Lübke

    2009-01-01

    BACKGROUND: The lysosomal 66.3 kDa protein from mouse is a soluble, mannose 6-phosphate containing protein of so far unknown function. It is synthesized as a glycosylated 75 kDa precursor that undergoes limited proteolysis leading to a 28 kDa N- and a 40 kDa C-terminal fragment. RESULTS: In order to gain insight into the function and the post-translational maturation process of

  12. Automatic localization of the da Vinci surgical instrument tips in 3-D transrectal ultrasound.

    PubMed

    Mohareri, Omid; Ramezani, Mahdi; Adebar, Troy K; Abolmaesumi, Purang; Salcudean, Septimiu E

    2013-09-01

    Robot-assisted laparoscopic radical prostatectomy (RALRP) using the da Vinci surgical system is the current state-of-the-art treatment option for clinically confined prostate cancer. Given the limited field of view of the surgical site in RALRP, several groups have proposed the integration of transrectal ultrasound (TRUS) imaging in the surgical workflow to assist with accurate resection of the prostate and the sparing of the neurovascular bundles (NVBs). We previously introduced a robotic TRUS manipulator and a method for automatically tracking da Vinci surgical instruments with the TRUS imaging plane, in order to facilitate the integration of intraoperative TRUS in RALRP. Rapid and automatic registration of the kinematic frames of the da Vinci surgical system and the robotic TRUS probe manipulator is a critical component of the instrument tracking system. In this paper, we propose a fully automatic registration technique based on automatic 3-D TRUS localization of robot instrument tips pressed against the air-tissue boundary anterior to the prostate. The detection approach uses a multiscale filtering technique to identify and localize surgical instrument tips in the TRUS volume, and could also be used to detect other surface fiducials in 3-D ultrasound. Experiments have been performed using a tissue phantom and two ex vivo tissue samples to show the feasibility of the proposed methods. Also, an initial in vivo evaluation of the system has been carried out on a live anaesthetized dog with a da Vinci Si surgical system and a target registration error (defined as the root mean square distance of corresponding points after registration) of 2.68 mm has been achieved. Results show this method's accuracy and consistency for automatic registration of TRUS images to the da Vinci surgical system. PMID:23674418

  13. PanDA Pilot Submission using Condor-G: Experience and Improvements

    SciTech Connect

    Zhao X.; Hover John; Wlodek Tomasz; Wenaus Torre; Frey Jaime; Tannenbaum Todd; Livny Miron

    2011-01-01

    PanDA (Production and Distributed Analysis) is the workload management system of the ATLAS experiment, used to run managed production and user analysis jobs on the grid. As a late-binding, pilot-based system, the maintenance of a smooth and steady stream of pilot jobs to all grid sites is critical for PanDA operation. The ATLAS Computing Facility (ACF) at BNL, as the ATLAS Tier1 center in the US, operates the pilot submission systems for the US. This is done using the PanDA 'AutoPilot' scheduler component which submits pilot jobs via Condor-G, a grid job scheduling system developed at the University of Wisconsin-Madison. In this paper, we discuss the operation and performance of the Condor-G pilot submission at BNL, with emphasis on the challenges and issues encountered in the real grid production environment. With the close collaboration of Condor and PanDA teams, the scalability and stability of the overall system has been greatly improved over the last year. We review improvements made to Condor-G resulting from this collaboration, including isolation of site-based issues by running a separate Gridmanager for each remote site, introduction of the 'Nonessential' job attribute to allow Condor to optimize its behavior for the specific character of pilot jobs, better understanding and handling of the Gridmonitor process, as well as better scheduling in the PanDA pilot scheduler component. We will also cover the monitoring of the health of the system.

  14. 11 CFR 111.12 - Subpoenas and subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4)). 111.12...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4))....

  15. 11 CFR 111.13 - Service of subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4)). 111.13...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4))....

  16. 11 CFR 111.12 - Subpoenas and subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4)). 111.12...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4))....

  17. 11 CFR 111.13 - Service of subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4)). 111.13...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4))....

  18. 11 CFR 111.12 - Subpoenas and subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4)). 111.12...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4))....

  19. 11 CFR 111.13 - Service of subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4)). 111.13...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4))....

  20. The characterization of the dopaminergic profile of EMD 23,448, an indolyl-3-butylamine: Selective actions on presynaptic and supersensitive postsynaptic DA receptor populations

    Microsoft Academic Search

    M. Goldstein; K. Fuxe; E. Meller; C. A. Seyfried; L. Agnati; F. M. Mascagni

    1987-01-01

    Summary The effects of the dopamine (DA) agonist EMD 23,448 on central normosensitive and supersensitive DA receptors were investigated. EMD 23,448 only slightly inhibits rat striatal DOPA synthesis in vivo and does not inhibit the enhanced striatal DOPA synthesis elicited by acute administration of haloperidol. Also unlike other DA agonists it does not increase striatal acetylcholine levels. However, it inhibits

  1. PROBABILIDADE DE RUÍNA COMO CRITÉRIO PARA DEFINIR O COEFICIENTE DE SEGURANÇA A SER USADO NA PREVISÃO DA CARGA ADMISSÍVEL DE FUNDAÇÕES POR ESTACAS

    Microsoft Academic Search

    Nelson Aoki; Mauro Leandro Menegotto; José Carlos; A. Cintra

    Resumo - A atual filosofia da Norma Brasileira NBR 6122\\/1996 de Projeto e Execução de Fundações baseia-se no conceito de coeficiente de segurança global ou parcial. O critério atual para a escolha do coeficiente de segurança global, quando a capacidade de carga da estaca é estimada a partir de métodos empíricos, é adotar o valor proposto pelo autor da teoria.

  2. Whole-genome sequences of DA and F344 rats with different susceptibilities to arthritis, autoimmunity, inflammation and cancer.

    PubMed

    Guo, Xiaosen; Brenner, Max; Zhang, Xuemei; Laragione, Teresina; Tai, Shuaishuai; Li, Yanhong; Bu, Junjie; Yin, Ye; Shah, Anish A; Kwan, Kevin; Li, Yingrui; Jun, Wang; Gulko, Pércio S

    2013-08-01

    DA (D-blood group of Palm and Agouti, also known as Dark Agouti) and F344 (Fischer) are two inbred rat strains with differences in several phenotypes, including susceptibility to autoimmune disease models and inflammatory responses. While these strains have been extensively studied, little information is available about the DA and F344 genomes, as only the Brown Norway (BN) and spontaneously hypertensive rat strains have been sequenced to date. Here we report the sequencing of the DA and F344 genomes using next-generation Illumina paired-end read technology and the first de novo assembly of a rat genome. DA and F344 were sequenced with an average depth of 32-fold, covered 98.9% of the BN reference genome, and included 97.97% of known rat ESTs. New sequences could be assigned to 59 million positions with previously unknown data in the BN reference genome. Differences between DA, F344, and BN included 19 million positions in novel scaffolds, 4.09 million single nucleotide polymorphisms (SNPs) (including 1.37 million new SNPs), 458,224 short insertions and deletions, and 58,174 structural variants. Genetic differences between DA, F344, and BN, including high-impact SNPs and short insertions and deletions affecting >2500 genes, are likely to account for most of the phenotypic variation between these strains. The new DA and F344 genome sequencing data should facilitate gene discovery efforts in rat models of human disease. PMID:23695301

  3. Loss of 45 Da from a2 Ions and Preferential Loss of 48 Da from a2 Ions Containing Methionine in Peptide Ion Tandem Mass Spectra

    NASA Astrophysics Data System (ADS)

    Simón-Manso, Yamil; Neta, Pedatsur; Yang, Xiaoyu; Stein, Stephen E.

    2011-02-01

    While analyzing tandem mass spectra of tryptic tripeptides, intense unassigned peaks were observed, corresponding to neutral loss of 45 Da from a2 ions. This process was confirmed by MS3 experiments. Based on exact mass analysis, the loss was ascribed to (NH3 + CO) or formamide. The proposed mechanism involves a cyclic form of the a2 ions. The structure of the a2 - 45 ions was confirmed by their fragmentation in MS3 experiments. Loss of (NH3 + CO) from the a2 ions occurs in competition with other paths, such as the loss of H2O or the formation of immonium ions. However, if the a2 ion contains methionine, a neutral loss of 48 Da (ascribed to CH3SH) predominates, and is followed by the loss of (NH3 + CO). These processes were confirmed by MS3 experiments. The intensity of the a2 - 48 peak formed from XaaMet has a maximum value of 42% (of the total intensity of all ions) for Xaa=Gly, varies between 15% and 40% for most other Xaa residues, is lower for residues that can undergo loss of water or ammonia, and is very low for Lys or Arg. When the order of the residues is reversed to MetXaa, the loss of 48 Da is much smaller. This effect can be used to determine the sequence of b2 ions containing Met in proteomic studies. Considerable loss of CH3SH is observed from doubly protonated tryptic tripeptides with N-terminal Met, but the loss is much less when they are singly protonated or when Met is in the center position.

  4. Can B cell epitopes of 60 kDa Ro distinguish systemic lupus erythematosus from Sjögren's syndrome?

    PubMed

    Scofield, A N; Kurien, B T; Gordon, T P; Scofield, R H

    2001-01-01

    Antibodies binding components of the Ro/La (or SSA/SSB) ribonucleoprotein particle are found in the sera of patients with systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS) as well as mothers who give birth to babies with neonatal lupus. Anti-La occurs in a subset of sera that contain anti-Ro, and anti-La is found more commonly in sera of patients with SS than in sera from SLE patients. The fine specificity of autoantibodies binding 60 kDa has been studied extensively. Recent data have suggested that there are disease-specific epitopes which identify patients with either SLE or SS. Alternatively, other data suggest that the B cell epitopes of 60kDa Ro vary according to the presence of anti-La. The present study was undertaken to determine whether binding of putative disease-specific 60 kDa Ro epitopes is associated with the diagnosis of SLE vs SS, or instead associated with the presence of anti-La. Anti-60 kDa Ro positive sera from 24 SLE patients and 44 SS patients were studied for antibodies binding two epitopes of 60 kDa Ro. We find the epitope defined by residues 171-190 is associated with anti-60 kDa Ro without anti-La, regardless of diagnosis. Meanwhile, binding of the epitope defined by residues 215-232 is not commonly found in anti-60 kDa Ro sera, especially in those sera with both anti-60 kDa Ro and anti-La. Thus, the fine specificity of antibody binding to 60 kDa Ro varies according to the presence of anti-La, not to the diagnosis of either SLE or SS. PMID:11530996

  5. Double D-?-A dye linked by 2,2'-bipyridine dicarboxylic acid: influence of para- and meta-substituted carboxyl anchoring group.

    PubMed

    Ganesan, Paramaguru; Chandiran, Aravind Kumar; Gao, Peng; Rajalingam, Renganathan; Grätzel, Michael; Nazeeruddin, Mohammad Khaja

    2015-04-01

    Starting from 2,2'-bipyridine dicarboxylic acid, two new (D-?-A)2 sensitizers, including m-DA with the carboxyl anchoring group substituted meta to the donor-bridge moiety and p-DA with a para-substituted anchoring group, were synthesized in order to evaluate the impact of the position of the anchoring group on the optical, electrochemical, and photovoltaic properties of dye-sensitized solar cells. p-DA exhibits red-shifted absorption behavior compared to m-DA, owing to the more efficiently extended ?-conjugation with para substitution. Both m-DA and p-DA are adsorbed on the mesoporous TiO2 surface by using both of their carboxylic acid groups in a bianchoring mode, which is confirmed through attenuated total reflectance FTIR analysis. Red-shifted absorption of p-DA assists the achievement of a red-shifted incident photon-to-electron conversion efficiency and a higher short-circuit current density than m-DA. The photogenerated electron lifetime in TiO2 is also found to be higher for para substituted p-DA than the meta-substituted m-DA, which results in a higher open-circuit voltage. All of the results suggest that dicarboxyl-2,2'-bipyridine can be used as an acceptor for metal-free organic sensitizers. However, the anchoring segments should be adjusted to the favorable position of the corresponding donor-bridge moieties for better conjugation. PMID:25656067

  6. Comparison of purified 12 kDa and recombinant 15 kDa Fasciola hepatica antigens related to a Schistosoma mansoni fatty acid binding protein.

    PubMed

    Hillyer, G V

    1995-01-01

    Vaccines in schistosomiasis using homologous antigens have been studied extensively in experimentally infected mammalian hosts. Vaccines using heterologous antigens have received comparatively less attention. This review summarizes recent work on a heterologous 12 kDa Fasciola hepatica antigenic polypeptide which cross reacts with Schistosoma mansoni. A cDNA has been cloned and sequenced, and the predicted amino acid sequence of the recombinant protein has been shown to have significant (44%) identity with a 14 kDa S. mansoni fatty acid binding protein. Thus in the parasitic trematodes fatty acid binding proteins may be potential vaccine candidates. The F. hepatica recombinant protein has been overexpressed and purified and denoted rFh15. Preliminary rFh15 migrates more slowly (i.e. may be slightly larger) than nFh12 on SDS-PAGE and has a predicted pI of 6.01 vs. observed pI of 5.45. Mice infected with F. hepatica develop antibodies to nFh12 by 2 weeks of infection vs. 6 weeks of infection to rFh15; on the other hand, mice with schistosomiasis mansoni develop antibodies to both nFh12 and rFh15 by 6 weeks of infection. Both the F. hepatica and S. mansoni cross-reactive antigens may be cross-protective antigens with the protection inducing capability against both species. PMID:8531666

  7. Comparison of the inhibitory effects of two types (90?kDa and 190?kDa) of hyaluronic acid on the expression of fibrinolytic factors in human synovial fibroblasts

    Microsoft Academic Search

    Tohgo Nonaka; Hiraku Kikuchi; Satoshi Sohen; Kanji Fukuda; Chiaki Hamanishi; Seisuke Tanaka

    2002-01-01

    Hyaluronic acid (HA) has been shown to be clinically effective, and is currently used for the treatment of arthropathy. We\\u000a previously reported that HA of molecular weight 90?kDa (90-HA) inhibits the fibrinolytic factors in human synovial fibroblasts.\\u000a In the present study, we investigated the effect of high molecular weight (190?kDa) HA (190-HA) compared with 90-HA on the\\u000a pericellular fibrinolytic system

  8. Double E1B 19 kDa- and E1B 55 kDa-deleted oncolytic adenovirus in combination with radiotherapy elicits an enhanced anti-tumor effect

    Microsoft Academic Search

    J Kim; P-H Kim; J Y Yoo; A-R Yoon; H J Choi; J Seong; I-W Kim; C-O Yun

    2009-01-01

    Radiation therapy, a mainstay for anti-tumor therapeutic regimens for a variety of tumor types, triggers tumor cell apoptotic pathways by either directly eliciting DNA damage or indirectly inducing the formation of oxygen radicals. In an effort to augment radiation therapy, we generated a double E1B 19 kDa- and E1B 55 kDa-deleted oncolytic adenovirus (Ad??E1B19\\/55). In combination with radiotherapy, greater cytotoxicity

  9. The Prolactin Gene is Expressed in the Hypothalamic-Neurohypophyseal System and the Protein is Processed Into a 14-kDa Fragment with Activity Like 16-kDa Prolactin

    Microsoft Academic Search

    Carmen Clapp; Luz Torner; Gabriel Gutierrez-Ospina; Eva Alcantara; Francisco J. Lopez-Gomez; Makoto Nagano; Paul A. Kelly; Salvador Mejia; Miguel A. Morales; Gonzalo Martinez de La Escalera

    1994-01-01

    The 23-kDa form of prolactin (PRL) has been proposed to function as both a mature hormone and a prohormone precursor for different uniquely bioactive forms of the molecule. We have shown that the 16-kDa N-terminal fragment of PRL (16K PRL) inhibits angiogenesis via a specific receptor. In addition, 16K PRL stimulates natriuresis and diuresis in the rat, and kidney membranes

  10. Crosslinking of hemin to a specific site on the 90-kDa ferritin repressor protein

    SciTech Connect

    Lin, Jihjing; Thach, R.E. (Washington Univ., St. Louis, MO (United States)); Patino, M.M.; Gaffield, L.; Walden. W.E. (Univ. of Illinois at Chicago (United States)); Smith, A. (Univ. of Missouri, Kansas City (United States))

    1991-07-15

    Incubation of a 90-kDa ferritin repressor protein (FRP) with small amounts of radiolabeled hemin resulted in the formation of a strong interaction between the two that was stable to SDS/PAGE. Of seven other proteins tested individually, only apohemopexin and bovine serum albumin showed similar crosslinking ability, albeit to a much lower extent. ({sup 14}C)Hemin specifically crosslinked to FRP in the presence of a 50-fold excess of total wheat germ proteins. Inclusion of catalase did not prevent the reaction of hemin with FRP, suggesting that H{sub 2}O{sub 2} is not involved. The subsequent addition of a stoichiometric amount of apohemopexin did not reverse the reaction. Exhaustive digestion of the complex with Staphylococcus aureus V8 protease produced a major labeled peptide of 17 kDa. These results show the existence of a highly specific, uniquely reactive hemin binding site on FRP.

  11. A 9 kDa antifreeze protein from the Antarctic springtail, Gomphiocephalus hodgsoni.

    PubMed

    Hawes, T C; Marshall, C J; Wharton, D A

    2014-08-01

    A 9 kDA antifreeze protein (AFP) was isolated and purified from the Antarctic springtail, Gomphiocephalus hodgsoni. By combining selective sampling procedures and a modified ice affinity purification protocol it was possible to directly isolate a single AFP protein without recourse to chromatographic separation techniques. Mass spectrometry identified a single 9 kDa component in the purified ice fraction. Intramolecular disulphide bonding was suggested by the presence of 12 cysteine residues. The specific amino acid composition is unique, particularly with regard to the presence of histidine (11.5%). But it also shows noticeable commonalities with insect AFPs in the abundance of cysteine (13.8%), while simultaneously hinting, through the presence of glycine (11.5%), that the metabolic building blocks of AFPs in Collembola may have a phylogenetically-determined component. PMID:25025820

  12. Maximizing use of robot-arm no. 3 in da vinci-assisted thoracic surgery.

    PubMed

    Kajiwara, Naohiro; Maeda, Junichi; Yoshida, Koichi; Kato, Yasufumi; Hagiwara, Masaru; Kakihana, Masatoshi; Ohira, Tatsuo; Kawate, Norihiko; Ikeda, Norihiko

    2015-05-01

    We have previously reported on the importance of appropriate robot-arm settings and replacement of instrument ports in robot-assisted thoracic surgery, because the thoracic cavity requires a large space to access all lesions in various areas of the thoracic cavity from the apex to the diaphragm and mediastinum and the chest wall. (1 - 3) Moreover, it can be difficult to manipulate the da Vinci Surgical System using only arms No. 1 and No. 2 depending on the tumor location. However, arm No. 3 is usually positioned on the same side as arm No. 2, and sometimes it is only used as an assisting-arm to avoid conflict with other arms ( Fig. 1 ). In this report, we show how robot-arm No. 3 can be used with maximum effectiveness in da Vinci-assisted thoracic surgery. [Figure: see text]. PMID:26011219

  13. [Freud's identification with men who had 2 mothers: Oedipus, Leonardo da Vinci, Michealangelo and Moses].

    PubMed

    Harsch, H E

    1994-02-01

    In view of the fact that as a child Sigmund Freud was looked after by two mothers--his actual mother and a nursemaid--it is hardly surprising that traces of this pre-oedipal situation, fraught as it was with traumatisation and loss, should be discernible in the works of the creator of psychoanalysis. Freud's continued preoccupation with the Oedipus myth, his interest in "great men" like da Vinci and Michelangelo, and finally his identification with the figure of Moses are pointers not only to the paternal dimension (as long suggested by Freud's biographers) but also to the maternal dimension and its significance for Freud's life and work. The author demonstrates that those mythical and historical figures which Freud identified with--Oedipus, da Vinci, Michelangelo, Moses--themselves all had two mothers and sublimated this traumatic experience into outstanding achievements, the same being true of Freud himself "who solved the famous riddle and was a most powerful man". PMID:8153361

  14. The recurrence interval of forest fires in Cabeço da Vaca (Cabreira Mountain--northwest of Portugal).

    PubMed

    Ferreira Leite, Flora; Bento Gonçalves, António; Vieira, António

    2011-02-01

    The recurrence of forest fires is degrading an important part of the Portuguese natural heritage namely its forest and soils. In this paper we present the case study of Cabeço da Vaca (Cabreira Mountain-northwest Portugal), where in recent decades, particularly in the 70s, there was a significant increase in the number of forest fires and in the areas scorched annually. There is thus a turning point between a period when fire was an integral part of the ecosystems and when fire has become a serious threat to woodland management and development (Bento Gonçalves, 2006). Starting with a thorough characterization of forest fires and based on the mapping of scorched areas between 1990 and 2006, we have proceeded to identify the annual pattern of maximum recurrence and the definition of the return interval in Cabeço da Vaca, producing thus a valuable document to support management and forestry development in general. PMID:20576260

  15. Iron abundance in the hot DA white dwarfs Feige 24 and G191 B2B

    NASA Technical Reports Server (NTRS)

    Vennes, Stephane; Chayer, Pierre; Thorstensen, John R.; Bowyer, Stuart; Shipman, Harry L.

    1992-01-01

    Attention is given to model calculations of the far- and extreme-UV line spectra of highly ionized Fe species (Fe IV, Fe V, and Fe VI) for hot high-gravity H-rich stars. A spectral analysis of 31 hr of exposure of the DA white dwarf Feige 24 with IUE in the echelle mode reveals the presence of Fe with an abundance relative to H by number of (5-10) x 10 exp -6 with an uncertainty dominated by the determination of stellar parameters. An analysis of IUE data from the white dwarf G191 B2B results in a similar Fe abundance if this star shares similar atmospheric parameters (Teff, g) with Feige 24. Fe is thus the second most abundant photospheric element in hot DA white dwarfs.

  16. Direct observation of microgalvanic couples on the surface of samples of solid combustible minerals

    SciTech Connect

    Kamneva, A.I.; Nikitin, K.N.; Spitsyna, N.G.

    1981-01-01

    The paper presents the results of an investigation of the surface of samples of Donbass anthracite by the microprobe method. The work of microgalvanic couples on the surface of the anthracite samples has been detected. An inhomogeneity of the structural fragments of the vitrinized part of anthracites has been determined by the electrochemical method. 7 refs.

  17. Servio Pblico Federal 16/08/13UNIVERSIDADE FEDERAL DE SANTA CATARINA

    E-print Network

    Floeter, Sergio Ricardo

    Departamento de Compras e LicitaçõVITRINE AMBIENTES P/ ESCRITÓRIO LTDA.e201380205316 SERVIÇOS LTDA MEe20138020554.310,0001-07-2013201305382 44905235Departamento de Compras e LicitaçõSPY INFORMÁTICA LTDAe01.080,0001-07-2013201305384 33903035Departamento de Compras e LicitaçõDWS COM. DE PROD. LAB

  18. LA VISITE AU ZOO Regards sur l'animal sauvage captif au XIXe sicle et dans l'entre-deux-guerres

    E-print Network

    Paris-Sud XI, Université de

    LA VISITE AU ZOO Regards sur l'animal sauvage captif au XIXe siècle et dans l'entre-deux-guerres À mobiles scientifiques initiaux, ces zoos deviennent des vitrines de la nature sauvage pour des populations, Palomba, 1935, p. 67. halshs-00659775,version1-13Jan2012 Manuscrit auteur, publié dans "L'animal sauvage

  19. Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography

    PubMed Central

    Lakomek, Kristina; Dickmanns, Achim; Kettwig, Matthias; Urlaub, Henning; Ficner, Ralf; Lübke, Torben

    2009-01-01

    Background The lysosomal 66.3 kDa protein from mouse is a soluble, mannose 6-phosphate containing protein of so far unknown function. It is synthesized as a glycosylated 75 kDa precursor that undergoes limited proteolysis leading to a 28 kDa N- and a 40 kDa C-terminal fragment. Results In order to gain insight into the function and the post-translational maturation process of the glycosylated 66.3 kDa protein, three crystal structures were determined that represent different maturation states. These structures demonstrate that the 28 kDa and 40 kDa fragment which have been derived by a proteolytic cleavage remain associated. Mass spectrometric analysis confirmed the subsequent trimming of the C-terminus of the 28 kDa fragment making a large pocket accessible, at the bottom of which the putative active site is located. The crystal structures reveal a significant similarity of the 66.3 kDa protein to several bacterial hydrolases. The core ???? sandwich fold and a cysteine residue at the N-terminus of the 40 kDa fragment (C249) classify the 66.3 kDa protein as a member of the structurally defined N-terminal nucleophile (Ntn) hydrolase superfamily. Conclusion Due to the close resemblance of the 66.3 kDa protein to members of the Ntn hydrolase superfamily a hydrolytic activity on substrates containing a non-peptide amide bond seems reasonable. The structural homology which comprises both the overall fold and essential active site residues also implies an autocatalytic maturation process of the lysosomal 66.3 kDa protein. Upon the proteolytic cleavage between S248 and C249, a deep pocket becomes solvent accessible, which harbors the putative active site of the 66.3 kDa protein. PMID:19706171

  20. Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke

    Microsoft Academic Search

    Zhen Zheng; Jong Youl Kim; Hualong Ma; Jong Eun Lee; Midori A Yenari

    2008-01-01

    The 70-kDa heat shock protein (Hsp70) is involved in protecting the brain from a variety of insults including stroke. Although the mechanism has been largely considered to be because of its chaperone functions, recent work indicates that Hsp70 also modulates inflammatory responses. To explore how and whether Hsp70 regulate immune responses in brain ischemia, mice overexpressing Hsp70 (Hsp Tg) were

  1. Molecular characterization and cloning of the 52kDa SSA\\/Ro protein

    Microsoft Academic Search

    Edward K. L. Chan; John C. Hamel; Carol L. Peebles; Jill P. Buyon; Eng M. Tan

    1990-01-01

    Autoantibodies to SS-A or Ro are common in patients with the systemic rheumatic diseases Sjogren's syndrome and lupus. In 1984, Wolin and Steitz showed that autoantibodies to SS-A\\/Ro recognized a family of low abundant ribonucleoprotein particles composed of hY-RNAs and a 60kDa protein component. The latter was the only major protein antigen observed by radiolabeled immunoprecipitation. Recent studies from this

  2. Cloning and expression of mouse 60 kDa ribonucleoprotein SSA\\/Ro

    Microsoft Academic Search

    Dunrui Wang; Jill P. Buyon; Edward K. L. Chan

    1996-01-01

    Autoantibodies to SS-A\\/Ro are among the most common found in sera of patients with systemic rheumatic diseases. These autoimmune diseases can affect various organ systems of the body and are variable in their manifestations and presentation. One of the autoimmune targets is the 60 kDa SS-A\\/Ro protein known to be associated with small cytoplasmic Y RNAs. To study systematically the

  3. Mycobacterium tuberculosis 6 kDa early secreted antigenic target stimulates activation of J774 macrophages

    Microsoft Academic Search

    Gyanesh Singh; Balwan Singh; Vladimir Trajkovic; Pawan Sharma

    2005-01-01

    The influence of the 6kDa early-secreted antigenic target (ESAT-6) of Mycobacterium tuberculosis on macrophage activation was investigated using J774 macrophage cell line. While without effect if applied alone, ESAT-6 in a dose-dependent manner enhanced nitric oxide (NO) release by IFN-?-stimulated J774 cells. However, it completely failed to modulate NO production in J774 cells activated with E. coli lipopolysaccharide. The effect

  4. On Ensino de Astronomia nas Cidades de Ribeirão Pires e Rio Grande da Serra

    NASA Astrophysics Data System (ADS)

    Faria, R. Z.; Voelzke, M. R.

    2007-08-01

    Apesar da astronomia ser um dos temas indicados pelos Parâmetros Curriculares Nacionais, observa-se que poucas mudanças ocorreram desde a implementação do mesmo em sala de aula. A presente pesquisa diz respeito sobre como os tópicos de astronomia estão sendo abordados pelos professores no ensino médio. Optou-se por aplicar um questionário com os professores que ministram a disciplina de física. Os mesmos trabalham em escolas estaduais situadas nas cidades de Ribeirão Pires e Rio Grande da Serra, ambas subordinadas a Diretoria de Ensino de Mauá, no Estado de São Paulo. O questionário foi aplicado durante o 2° semestre de 2006. Até o momento os resultados são preliminares. Dos 82,0% dos professores que responderam ao questionário no município de Rio Grande da Serra, 66,7% não aplicaram nenhum tópico de astronomia, 77,8% não utilizaram qualquer tipo de programa computacional, 66,7% não utilizaram laboratório, que 77,8% nunca levaram os alunos a museus e ou planetários e que 66,7% não indicaram qualquer tipo de revista ou livro sobre astronomia aos seus alunos. No município de Ribeirão Pires, 53,3% dos professores responderam ao questionário, destes 75,0% não aplicaram nenhum tópico de astronomia, 93,8% não utilizaram qualquer tipo de programa computacional, 75,0% não utilizaram laboratório, 81,3% nunca levaram os alunos a museus e ou planetário e 56,3% não indicaram qualquer tipo de revista ou livro sobre astronomia ao seus alunos. Apesar da maioria dos professores reconhecerem que o conteúdo de astronomia influi na formação do jovem, os mesmos não incluem o tema em seus planejamentos escolares.

  5. Characterisation of Fasciola gigantica adult 27-kDa excretory-secretory antigen in human fascioliasis

    Microsoft Academic Search

    C. Tantrawatpan; W. Maleewong; C. Wongkham; S. Wongkham; P. M. Intapan; K. Nakashima

    2003-01-01

    The 27-kDa excretory-secretory antigen partially purified from adult Fasciola gigantica adult worms (FG27) has been used as the sensitive and specific antigen for immunodiagnosis of human fascioliasis. Lectin-blot analyses have shown that the FG27 possesses both N - and O -glycans. In two-dimensional electrophoresis, silver staining, lectin blotting and immunoblotting, FG27 displayed at least four antigenic-glycosylated protein spots at the

  6. Primary Structure of the 170-kDa Surface Lectin of Pathogenic Entamoeba histolytica

    Microsoft Academic Search

    Egbert Tannich; Frank Ebert; Rolf D. Horstmann

    1991-01-01

    The adherence of Entamoeba histolytica to colonic mucins and to host cells appears to be predominantly mediated by a 170-kDa surface lectin of the amoebae. By using an antiserum to the purified lectin, the corresponding cDNA was isolated from an expression library of the pathogenic E. histolytica isolate HM-1:IMSS. Northern blot analysis indicated a transcript of ≈4 kilobases, and Southern

  7. Analysis of the 170-kDa lectin gene promoter of Entamoeba histolytica

    Microsoft Academic Search

    Heidrun Buß; Chrissostomos Lioutas; Sabine Dobinsky; Rose Nickel; Egbert Tannich

    1995-01-01

    The promoter region driving the gene for the 170-kDa heavy subunit of the Entamoeba histolytica galactose-inhibitable lectin was analysed by transient transfection using the chloramphenicol acetyltransferase gene as reporter. S1 mapping confirmed our previous notion that the promoter is located within a 1.35-kb intergenic sequence preceding the structural lectin gene. Transcripts derived from the chloramphenicol acetyltransferase gene of transfected trophozoites

  8. The Design of Intelligent Monitoring System Based on DaVinci Platform

    Microsoft Academic Search

    Pan Zhao; Zhi liang Jiang

    2012-01-01

    In this paper, an embedded video monitoring system for intelligent control is presented. This presented system uses DaVinci-based high-speed TMS320DM6467 chip as hardware component and uses Embedded Linux Operating System as software component, in addition, it takes target detection and tracking algorithms as its core. So it can not only meet the requirements of real-time video processing and heavy computation

  9. Research of the orbital evolution of asteroid 2012 DA14 (in Russian)

    NASA Astrophysics Data System (ADS)

    Zausaev, A. F.; Denisov, S. S.; Derevyanka, A. E.

    Research of the orbital evolution of asteroid 2012 DA14 on the time interval from 1800 to 2206 is made, an object close approaches with Earth and the Moon are detected, the probability of impact with Earth is calculated. The used mathematical model is consistent with the DE405, the integration was performed using a modified Everhart's method of 27th order, the probability of collision is calculated using the Monte Carlo method.

  10. Importância da fisioterapia no pré e pós-operatório de cirurgia cardíaca pediátrica

    Microsoft Academic Search

    Simone Cavenaghi; Silvia Cristina Garcia de Moura; Thalis Henrique da Silva; Talita Daniela Venturinelli; Lais Helena Carvalho Marino; Neuseli Marino Lamari

    2009-01-01

    Resumo Complicações no pós-operatório de cirurgia cardíaca pediátrica são freqüentes, destacando-se a atelectasia e a pneumonia. A fisioterapia contribui significativamente no tratamento destas complicações. Desta forma, este estudo buscou agrupar e atualizar os conhecimentos da atuação fisioterapêutica no pré-operatório e nas complicações pulmonares do pós-operatório de cirurgia cardíaca pediátrica. Observou-se a eficácia do tratamento fisioterapêutico por meio de diferentes técnicas

  11. BAL Surfactant Protein A and Clara Cell 10-kDa Protein Levels in Healthy Subjects

    Microsoft Academic Search

    N. Shijubo; Y. Honda; Y. Itoh; T. Yamaguchi; Y. Kuroki; T. Akino; T. Kawai; S. Abe

    1998-01-01

    .   Lung surfactant protein A (SP-A) and Clara cell 10-kDa protein (CC10) are the most abundant proteins produced locally in\\u000a the lower respiratory tract, as assessed in bronchoalveolar lavage (BAL) analysis. However, it is not known what factors influence\\u000a SP-A and CC10 levels in BAL fluids, and the relationship between SP-A and CC10 levels in BAL fluids has been unclear.

  12. Software architecture of the longitudinal feedback system for PEP-II, ALS and DA?NE

    Microsoft Academic Search

    R. Claus; J. Fox; I. Linscott; G. Oxoby; W. Ross; L. Sapozhnikov; D. Teytelman; A. Drago; M. Serio

    1995-01-01

    We describe the software architecture of the Longitudinal Feedback System being built for the PEP-II B-Factory at SLAG, the ALS light source at LBL and the DA?NE phi factory at Frascati. This VME\\/VXI based system utilizes commercially available embedded CPU controller boards running the VxWorks real time operating system. The operator interface for PEP-II and ALS is based on the

  13. Microscopic Observations on the Origin of Defects During Machining of Direct Aged (DA) Inconel 718 Superalloy

    Microsoft Academic Search

    G. K. Dosbaeva; S. C. Veldhuis; A. Elfizy; G. Fox-Rabinovich; T. Wagg

    2010-01-01

    Surface quality of advanced superalloys after machining is one of the major issues in the aerospace industry because it directly\\u000a affects service characteristics of the machined part. Tool life of cemented carbide inserts with the TiAlN coating during\\u000a machining of direct aged DA 718 alloys under roughing and finishing conditions has been under study. The defect origin on\\u000a the surface

  14. CaDaDis: A Tool for Displaying the Behavior of Cognitive Models and Agents

    Microsoft Academic Search

    Kevin Tor; Frank E. Ritter; Steven R. Haynes; Mark A. Cohen

    We introduce an extension to an architecture-independent tool (VISTA) for creating displays of cognitive model behavior, the Categorical Data Display (CaDaDis). Our display offers several views of categorical data. It includes a standard Pert Chart showing tasks by category (or resource), a Nonstandard Pert Chart that shows the temporal dependencies, and a Gantt chart that helps show occurrences of agent

  15. A Test of the Use of Hot DA White Dwarfs to Calibrate AB-Magnitude Photometry

    Microsoft Academic Search

    Tim Axelrod; Edward Olszewski; Abi Saha; Chuck Claver

    2007-01-01

    Proposed all-sky surveys wish to have photometry on an energy-based system (AB magnitudes, for instance). Two important projects requiring such photometry are luminosity distances of supernovae and high quality photometric redshifts. In order to achieve sub-1% energy-based photometry, hot DA White Dwarfs (WDs) with spectroscopically determined T_eff and log(g) and model-atmosphere spectral-energy distributions (SEDs) are needed as standards. What is

  16. Comparing the da Vinci Si Single Console and Dual Console in Teaching Novice Surgeons Suturing Techniques

    PubMed Central

    Jackson, Tiffany; Advincula, Arnold

    2014-01-01

    Background and Objectives: Robot-assisted laparoscopic surgery is often taught with the surgical mentor at the surgeon console and the trainee at the patient's bedside. The da Vinci dual console (Intuitive Surgical, Sunnyvale, California) allows a surgical mentor to teach with both the mentor and the trainee working at a surgeon console simultaneously. The purpose of this study is to evaluate the effectiveness of the dual console versus the single console for teaching medical students robotic tasks. Methods: Forty novice medical students were randomized to either the da Vinci single-console or dual-console group and were taught 4 knot-tying techniques by a surgical mentor. The students were timed while performing the tasks. Results: No statistically significant differences in mean task times were observed between the single- and dual-console groups: interrupted stitch with a 2-handed knot (300 seconds for single vs 294 seconds for dual, P = .59), interrupted stitch with a 1-handed knot (198 seconds for single vs 212 seconds for dual, P = .88), figure-of-8 stitch with a 2-handed knot (261 seconds for single vs 219 seconds for dual, P = .20), and figure-of-8 stitch with a 1-handed knot (200 seconds for single vs 199 seconds for dual, P = .53). Conclusion: No significant difference was observed in performance time when teaching knot-tying techniques to medical students using the da Vinci dual console compared with the single console. More research needs to be performed on the utility of the da Vinci dual console in surgical training. PMID:25392618

  17. A 10-bit 1-GSample\\/s Nyquist current-steering CMOS D\\/A converter

    Microsoft Academic Search

    A. Van den Bosch; M. Borremans; M. Steyaert; W. Sansen

    2000-01-01

    In this paper, a 10 bit 1 GS\\/s current-steering CMOS D\\/A converter is presented. The measured INL is better than +\\/-0.2 LSB. The 1 GS\\/s conversion rate has been obtained by a fully custom designed thermometer decoder. The dynamic limitations have been solved, resulting in more than 61 dB measured SFDR in the interval from DC to Nyquist at all

  18. 27 kDa Fasciola gigantica Glycoprotein for the Diagnosis of Prepatent Fasciolosis in Cattle

    Microsoft Academic Search

    S. Ghosh; P. Rawat; R. Velusamy; D. Joseph; S. C. Gupta; B. P. Singh

    2005-01-01

    An indirect enzyme-linked immunosorbent assay (ELISA) using 27 kDa glycoprotein of Fasciola gigantica has been evaluated for its potential use in the diagnosis of bovine fasciolosis. Following experimental infection of rabbits, F. gigantica infection-induced antibodies were isolated and later used as ligands in affinity chromatography for isolation of infection-induced antibody-specific proteins. Among the five infection-specific proteins isolated, a glycoprotein of

  19. MA092 Geometria plana e analitica Comprimento da circunfer^encia -Area de superficies planas

    E-print Network

    Gomes, Francisco A. M.

    MA092 ­ Geometria plana e anal´itica Comprimento da circunfer^encia - ´Area de superf´icies planas uma volta: 2R = D 61, 5 cm Dist^ancia total: 10.000.000 cm N´umero de voltas: 10.000.000/(61, 5) 51 - IMECC)MA092 ­ Geometria plana e anal´itica Agosto de 2013 5 / 22 ´Areas Ret^angulo ´Area AR = b · h

  20. Lmite de prazas para o curso 2014-2015 Consello de Goberno da UDC 27 de marzo de 2014

    E-print Network

    Fraguela, Basilio B.

    Proposto polo centro 2013-2014 Proposto polo centro 2014-2015 Mestrado Universitario en Acuicultura-2015 Consello de Goberno da UDC 27 de marzo de 2014 TITULACIÓNS Proposto polo centro 2013-2014 Proposto polo

  1. 32 CFR 644.425 - Authority and procedure for disposal of surplus property by DA to eligible public agencies.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 true Authority and procedure for disposal of surplus property by DA to eligible public agencies...CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal Disposal of Fee-Owned Real Property and Easement...

  2. Detection of circulating 54 kDa antigen in sera of bovine calves experimentally infected with F. gigantica.

    PubMed

    Velusamy, R; Singh, B P; Sharma, R L; Chandra, D

    2004-01-30

    The antibody response and circulating antigen levels in bovine calves, infected experimentally with Fasciola gigantica, were monitored using enzyme-linked immunoelectrotransfer blot (EITB) and sandwich ELISA, respectively. By EITB, the infected calves' sera recognized the polypeptides in the range of 54-58 kDa as early as 2 weeks post-infection. By 12th week post-infection, the lower two polypeptides of 12 and 8 kDa had disappeared. In sandwich ELISA, the circulating 54 kDa and whole worm antigen of F. gigantica were detected in the sera samples of infected calves as early as 2 weeks post-infection and persisted until the end of experiment (26th week PI). The 54 kDa antigen of F. gigantica appears to be specific and possesses promising immunodiagnostic potential for early prepatent diagnosis of bovine fasciolosis. PMID:14746978

  3. A new fibrinolytic enzyme (55?kDa) from Allium tuberosum: purification, characterization, and comparison.

    PubMed

    Chung, Dong-Min; Choi, Nack-Shick; Chun, Hyo Kon; Maeng, Pil Jae; Park, Sang-Bong; Kim, Sung-Ho

    2010-12-01

    Chives have been used both as food and as medicine. Previously, two fibrinolytic enzymes, ATFE-I (90 kDa) and ATFE-II (55 kDa), were identified in chives (Allium tuberosum), a perennial herb. In the present work, ATFE-II was purified by ion-exchange chromatography followed by gel filtration. In addition, the enzyme properties of ATFE-I and ATFE-II were compared. The molecular mass and isoelectric point (pI value) of ATFE-II were 55 kDa and pI 4.0, respectively, as revealed using one- or two-dimensional fibrin zymography. ATFE-II was optimally active at pH 7.0 and 45°C. ATFE-II degraded the A?-chain of human fibrinogen but did not hydrolyze the B?-chain or the ?-chain, indicating that the enzyme is an ?-fibrinogenase. The proteolytic activity of ATFE-II was completely inhibited by 1 mM leupeptin, indicating that the enzyme belongs to the cysteine protease class. ATFE-II was also inhibited by 1 mM Fe²(+). ATFE-II exhibited high specificity for MeO-Suc-Arg-Pro-Tyr-p-nitroaniline (S-2586), a synthetic chromogenic substrate of chymotrypsin. Thus proteolytic enzymes from A. tuberosum may be useful as thrombolytic agents. PMID:20954802

  4. John Chalmers DaCosta (1863-1933): restoration of the old operating table.

    PubMed

    Peters, Madalyn G; Berger, Adam C; Schwartz, Gordon F; Yeo, Charles J; Cowan, Scott W

    2013-03-01

    John Chalmers DaCosta was an influential chairman and the first Samuel D. Gross Professor of Surgery at Jefferson Medical College in Philadelphia. He was well known throughout the field as a skilled surgeon, passionate speaker, and exceptional writer. In addition to countless accomplishments during his career, DaCosta was deeply dedicated to the preservation and commemoration of surgical history. This ideology was exemplified when he set out on a mission to recover the old wooden operating table used by many of his iconic mentors including Samuel D. Gross, Joseph Pancoast, and William W. Keen. This table was originally used for surgical demonstrations and anatomy lessons in a lecture room of the Ely Building and later in the great amphitheater of the Jefferson Sansom Street Hospital. It was found forgotten in the basement of the College Building and was promptly refurbished, donned with dedicatory plaques, and returned to its honored position in the medical college. Dr. DaCosta also contributed a detailed article recalling the history of the table and the notable leaders in surgery who taught and practiced on its surface. The old table currently stands proudly in the entranceway of the Department of Surgery where it will remain as a cherished symbol of the early beginnings of surgical practice and education. PMID:23461945

  5. Characterisation of Fasciola gigantica adult 27-kDa excretory-secretory antigen in human fascioliasis.

    PubMed

    Tantrawatpan, C; Maleewong, W; Wongkham, C; Wongkham, S; Intapan, P M; Nakashima, K

    2003-10-01

    The 27-kDa excretory-secretory antigen partially purified from adult Fasciola gigantica adult worms (FG27) has been used as the sensitive and specific antigen for immunodiagnosis of human fascioliasis. Lectin-blot analyses have shown that the FG27 possesses both N - and O -glycans. In two-dimensional electrophoresis, silver staining, lectin blotting and immunoblotting, FG27 displayed at least four antigenic-glycosylated protein spots at the pI values of 4.8, 4.9, 5.2 and 5.4, respectively. After removing glycan moieties from the antigen by alkaline treatment, the molecular mass of the FG27 was reduced to 26.5 kDa as a prominent deglycosylated band. Immunoblotting analysis has revealed that the 26.5-kDa band reacts with the pooled human fascioliasis sera without any loss of antigenicity. These results suggest that the major antigenicity of the FG27 is due to its protein epitopes. PMID:14574564

  6. Development of 116 kDa Fraction for Detecting Experimental Toxoplasma gondii Infections in Mice

    PubMed Central

    HASSANAIN, Mohey Abdel-Hafez; ABDEL-RAHMAN, Eman Hussien; TOALEB, Nagwa Ibrahim; SHAAPAN, Raafat Mohamed; ELFADALY, Hasan Ali; HASSANAIN, Nawal Abdel-Hafez

    2013-01-01

    Background Serological diagnosis of Toxoplasma gondii infection using crude antigens may not be more accurate. To increase the diagnostic potency of antigens, isolation of their immunogenic fractions could be useful. The current research adopted to obtain an affinity isolated fraction from RH strain using CNBr Sepharose 4B column coupled with infected mice sera helping in detection of IgM and IgG of toxoplasmosis due to RH strain and other strains. Methods The isolated fraction was characterized by SDS-PAGE. Moreover, the diagnostic potency of the fraction was assessed by indirect ELISA in mice experimentally infected with RH strain and two other local strains; one of sheep origin and the other of human origin. Results The fraction was found to be consisted of a single band of 116 kDa compared with 17 bands ranged from 116 to 16 kDa associated with crude extract. The fraction proved potent diagnostic potentials of acute and chronic mice toxoplasmosis. Where it was detected both IgM and IgG antibodies as early as two days and as late as 2 months post experimental infection with any of the three strains. The level of detected IgM and IgG by RH fraction was higher in mice infected with RH strain than with local strains except IgM due to sheep strain parasite. Conclusions The 116 kDa fraction of T. gondii tachyzoites can be considered as a candidate in improving of serodiagnosisof Toxoplasma infections. PMID:24454439

  7. Shark cartilage 14?kDa protein as a dendritic cells activator.

    PubMed

    Safari, Elahe; Hassan, Zuhair M; Moazzeni, Seyed Mohammad

    2015-04-01

    Low molecular weight components of shark cartilage are reported to have anti-tumor as well as immuno-stimulating effects. Dendritic cells (DCs) are potent antigen-presenting cells (APCs) that have a key role in establishment of anti-cancer immune response. In this study, the effect of 14?kDa protein from shark cartilage was investigated on stimulation and maturation of dendritic cells. The isolated 14?kDa protein from shark cartilage extract was added to DCs medium during overnight culture and their maturation and T cells stimulation potential was investigated. The majority of shark-cartilage-treated DCs expressed higher levels of maturation markers and were more effective in stimulation of allogenic T cells compared with non-treated DCs (p?Da protein can potentially be used in DC-mediated T-cells stimulation and induction of desirable immune responses in clinical trials such as cancer immunotherapy. However, further studies are required to examine this proposal. PMID:25669314

  8. Pubertal isolation alters latent inhibition and DA in nucleus accumbens of adult rats.

    PubMed

    Shao, Feng; Jin, Jian; Meng, Qingxuan; Liu, Mei; Xie, Xi; Lin, Wenjuan; Wang, Weiwen

    2009-09-01

    Puberty is a critical period for neurodevelopment of schizophrenia. In the present study, we investigated the effects of peri-pubertal social isolation on psychotic behaviors in rats and its relationship to dopamine expression. Wistar male rats were randomly divided into pubertal isolation (ISO; isolate housing, 38-51 days of age) and social (SOC) groups. Latent inhibition (LI) and behavior in open field were tested during adolescence and adulthood. After the behavioral test, dopamine (DA) levels were measured in the medial prefrontal cortex (mPFC), nucleus accumbens (NAC), caudate-putamen (CPU), and the hippocampus (HIP). Pubertal social isolation impaired LI and increased the DA level in the NAC of young adult rats, but not adolescent rats, and enhanced open field locomotor activity in both adolescent and young adult rats. These data suggest that development of an LI deficit can be induced by social isolation during puberty after a developmental delay, and that NAC DA maybe involved in this process, which may mirror some aspects of the ontogency of schizophrenic symptoms. PMID:19527740

  9. Characterization of a 23-kDa protein associated with CD40.

    PubMed Central

    Morio, T; Hanissian, S; Geha, R S

    1995-01-01

    CD40 is a 45-kDa glycoprotein member of the tumor necrosis factor receptor (TNFR) family expressed on B cells, thymic epithelial cells, dendritic cells, and some carcinoma cells. The unique capacity of CD40 to trigger immunoglobulin isotype switching is dependent on the activation of protein-tyrosine kinases, yet CD40 possesses no kinase domain and no known consensus sequences for binding to protein-tyrosine kinases. Recently, an intracellular protein (CD40bp/LAP-1/CRAF-1) which belongs to the family of TNFR-associated proteins was reported to associate with CD40. We describe a 23-kDa cell surface protein (p23) which is specifically associated with CD40 on B cells and on urinary bladder transitional carcinoma cells. Protein microsequencing revealed that p23 shows no homology to any known protein. A rabbit antibody raised against a peptide derived from p23 recognized a 23-kDa protein in CD40 immunoprecipitates. In contrast to CD40bp/LAP-1/CRAF-1, p23 was not associated with TNFR p80 (CD120b). These findings suggest that p23 is a novel member of the CD40 receptor complex. Images Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5 Fig. 6 PMID:8524818

  10. Optimizing Capillary Electrophoresis for Top-Down Proteomics of 30–80 kDa Proteins

    PubMed Central

    Li, Yihan; Compton, Philip D.; Tran, John C.; Ntai, Ioanna; Kelleher, Neil L.

    2014-01-01

    The direct analysis of intact proteins via mass spectrometry offers compelling advantages in comparison to alternative methods due to the direct and unambiguous identification and characterization of protein sequences it provides. The inability to efficiently analyze proteins in the ‘middle mass range’, defined here as proteins from 30–80 kDa, in a robust fashion has limited the adoption of these “top-down” methods. Largely a result of poor liquid chromatographic performance, the limitations in this mass range may be addressed by alternative separations that replace chromatography. Herein, the short migration times of capillary zone electrophoresis-electrospray ionization-tandem mass spectrometry (CZE-ESI-MS/MS) have been extended to size-sorted whole proteins in complex mixtures from Pseudomonas aeruginosa PA01. An electrokinetically pumped nanospray interface, a coated capillary and a stacking method for on-column sample concentration were developed to achieve high loading capacity and separation resolution. We achieved full width at half maximum of 8–16 seconds for model proteins up to 29 kDa and identified 30 proteins in the mass range of 30–80 kDa from Pseudomonas aeruginosa PA01 whole cell lysate. These results suggest that CZE-ESI-MS/MS is capable of identifying proteins in the middle mass range in top-down proteomics. PMID:24596178

  11. Influenza viruses induce autoantibodies to a brain-specific 37-kDa protein in rabbit.

    PubMed Central

    Laing, P; Knight, J G; Hill, J M; Harris, A G; Oxford, J S; Webster, R G; Markwell, M A; Paul, S M; Pert, C B

    1989-01-01

    Immunization of rabbits with certain H1N1 influenza viruses, including the neurotropic strains NWS/33 and WSN/33 and the New Jersey/76 strain, resulted in the production of autoantibodies to a brain-specific protein of 37 kDa that is present in various species, including humans. Autoantibodies were produced to brain only; various other tissues tested were negative. These antibodies were not elicited by other influenza A or B viruses, including closely related recombinant strains, but were elicited by the isolated hemagglutinin of A/Bellamy/42 strain and by formaldehyde-fixed WSN virus--demonstrating that infection was not essential for the induction of autoantibodies. In histological studies, reaction with anti-viral antisera was specific to gray matter and was confined to sera that recognized the 37-kDa protein. Antibody binding was prominent in regions comprised of neuronal cell bodies in cellular layers of the dentate gyrus, hippocampus, cerebral cortex, and cerebellum and was undetectable in myelin-rich regions, such as the corpus callosum. The 37-kDa protein, therefore, appears to be a neuronal antigen. Antibodies directed against this protein may be involved in the pathogenesis of one or more of the neuropsychiatric disorders that occur after infection with influenza. Images PMID:2467294

  12. Microscopic Observations on the Origin of Defects During Machining of Direct Aged (DA) Inconel 718 Superalloy

    NASA Astrophysics Data System (ADS)

    Dosbaeva, G. K.; Veldhuis, S. C.; Elfizy, A.; Fox-Rabinovich, G.; Wagg, T.

    2010-11-01

    Surface quality of advanced superalloys after machining is one of the major issues in the aerospace industry because it directly affects service characteristics of the machined part. Tool life of cemented carbide inserts with the TiAlN coating during machining of direct aged DA 718 alloys under roughing and finishing conditions has been under study. The defect origin on the surface of the machined part was investigated. Metallographic observations of the DA 718 were made using optical metallography and SEM/EDS. To find out the origins of surface defect formation, the morphology of machined parts and cross sections of the machined surfaces have been investigated. Two major categories of defects were detected on the surface of the machined part: cracks and tears. The origin of the cracks on the machined surface is related to shearing of the primary complex TiC/NbC carbide revealed in a structure of DA 718 alloy. At the same time, Nb-rich regions of the primary complex carbide interact with the environment (oxygen from air) during machining with further formation of low strength oxide layer on the surface, forming tears.

  13. Disparate Locations of the 52- and 60-kDa Ro\\/SSA Antigens in Cultured Human Keratinocytes

    Microsoft Academic Search

    Jennifer Anne Yell; Lixiang Wang; Hongliang Yin; Daniel P. McCauliffe

    1996-01-01

    Anti-52- and anti-60-kDa Ro\\/SS-A (Ro) autoantibodies are produced by most patients with subacute cutaneous lupus erythematosus and neonatal lupus erythematosus and are thought to be pathogenic in these two disorders. To learn more about the epidermal antigens targeted by Ro autoantibodies, a panel of anti-52 and anti-60-kDa Ro antibodies was purified from human autoimmune sera and rabbit anti- sera and

  14. Intracellular degradation of apolipoprotein B generates an N-terminal 70 kDa fragment in the endoplasmic reticulum

    Microsoft Academic Search

    Susan M. Sallach; Khosrow Adeli

    1995-01-01

    Regulated apoB degradation in HepG2 cells occurs in the endoplasmic reticulum (ER), is catalyzed by an N-acetylleucylleucylnorleucinal (ALLN)-sensitive proteinase, and generates a specific 70 kDa fragment (Du, E. et al. (1994) J. Biol. Chem. 269, 9166–9175). In the present report, we have characterized the 70 kDa fragment by immunoprecipitation of permeabilized HepG2 cells with a battery of monoclonal antibodies against

  15. Detection of circulating 54 kDa antigen in sera of bovine calves experimentally infected with F. gigantica

    Microsoft Academic Search

    R. Velusamy; B. P. Singh; R. L. Sharma; D. Chandra

    2004-01-01

    The antibody response and circulating antigen levels in bovine calves, infected experimentally with Fasciola gigantica, were monitored using enzyme-linked immunoelectrotransfer blot (EITB) and sandwich ELISA, respectively. By EITB, the infected calves’ sera recognized the polypeptides in the range of 54–58kDa as early as 2 weeks post-infection. By 12th week post-infection, the lower two polypeptides of 12 and 8kDa had disappeared.

  16. Norms and cut off scores for the autism spectrum disorders diagnosis for adults (ASD-DA) with intellectual disability

    Microsoft Academic Search

    Johnny L. Matson; Jessica A. Boisjoli; Melissa L. González; Kimberly R. Smith; Jonathan Wilkins

    2007-01-01

    Establishing the cut-off scores for Autism Spectrum Disorder-Diagnostic (ASD-DA) scale for adults with intellectual disability (ID) and autism or PDD-NOS was the primary goal of this investigation. The aim of Study 1 was to determine if the ASD-DA was able to differentiate between adults with ID with and without an autism spectrum disorder, and to determine a total score cut-off

  17. Histopathological effects and determination of the putative receptor of Bacillus thuringiensis Cry1Da toxin in Spodoptera littoralis midgut.

    PubMed

    BenFarhat-Touzri, Dalel; Saadaoui, Marwa; Abdelkefi-Mesrati, Lobna; Saadaoui, Imen; Azzouz, Hichem; Tounsi, Slim

    2013-02-01

    Bacillus thuringiensis subsp. aizawai strain HD133, known by its effectiveness against Spodoptera species, produces many insecticidal proteins including Cry1Ab, Cry1Ca and Cry1Da. In the present study, the insecticidal activity of Cry1Da against Spodoptera littoralis was investigated. It showed toxicity with an LC(50) of 224.4 ng/cm(2) with 95% confidence limits of (178.61-270.19) and an LC(90) of 467.77 ng/cm(2) with 95% confidence limits of (392.89-542.65). The midgut histopathology of Cry1Da fed larvae showed vesicle formation in the apical region, vacuolization and destruction of epithelial cells. Biotinylated-activated Cry1Da toxin bound protein of about 65 kDa on blots of S. littoralis brush border membrane preparations. This putative receptor differs in molecular size from those recognized by Cry1C and Vip3A which are active against this polyphagous insect. This difference in midgut receptors strongly supports the use of Cry1Da as insecticidal agent, particularly in case of Cry and/or Vip-resistance management. PMID:23220238

  18. AN IMPROVED SPECTROSCOPIC ANALYSIS OF DA WHITE DWARFS FROM THE SLOAN DIGITAL SKY SURVEY DATA RELEASE 4

    SciTech Connect

    Tremblay, P.-E.; Bergeron, P.; Gianninas, A., E-mail: tremblay@astro.umontreal.ca, E-mail: bergeron@astro.umontreal.ca, E-mail: gianninas@astro.umontreal.ca [Departement de Physique, Universite de Montreal, C.P. 6128, Succ. Centre-Ville, Montreal, Quebec H3C 3J7 (Canada)

    2011-04-01

    We present an improved spectroscopic and photometric analysis of hydrogen-line DA white dwarfs from the Sloan Digital Sky Survey Data Release 4 (SDSS DR4) based on model atmospheres that include improved Stark broadening profiles with non-ideal gas effects. We also perform a careful visual inspection of all spectroscopic fits with high signal-to-noise ratios (S/Ns > 12) and present improved atmospheric parameters (T{sub eff} and log g) for each white dwarf. Through a comparison of spectroscopic and photometric temperatures, we report the discovery of 35 DA+DB/DC double degenerate candidates and two helium-rich DA stars. We also determine that a cutoff at S/N = 15 optimizes the size and quality of the sample for computing the mean mass of DA white dwarfs, for which we report a value of 0.613 M{sub sun}. We compare our results to previous analyses of the SDSS DR4 and find a good agreement if we account for the shift produced by the improved Stark profiles. Finally, the properties of DA white dwarfs in the SDSS are weighed against those of the Villanova White Dwarf Catalog sample of Gianninas et al. We find systematically lower masses (by about 3% on average), a difference that we trace back to the data reduction procedure of the SDSS. We conclude that a better understanding of these differences will be important to determine the absolute temperature scale and mean mass of DA white dwarfs.

  19. OpenDA Open Source Generic Data Assimilation Environment and its Application in Process Models

    NASA Astrophysics Data System (ADS)

    El Serafy, Ghada; Verlaan, Martin; Hummel, Stef; Weerts, Albrecht; Dhondia, Juzer

    2010-05-01

    Data Assimilation techniques are essential elements in state-of-the-art development of models and their optimization with data in the field of groundwater, surface water and soil systems. They are essential tools in calibration of complex modelling systems and improvement of model forecasts. The OpenDA is a new and generic open source data assimilation environment for application to a choice of physical process models, applied to case dependent domains. OpenDA was introduced recently when the developers of Costa, an open-source TU Delft project [http://www.costapse.org; Van Velzen and Verlaan; 2007] and those of the DATools from the former WL|Delft Hydraulics [El Serafy et al 2007; Weerts et al. 2009] decided to join forces. OpenDA makes use of a set of interfaces that describe the interaction between models, observations and data assimilation algorithms. It focuses on flexible applications in portable systems for modelling geophysical processes. It provides a generic interfacing protocol that allows combination of the implemented data assimilation techniques with, in principle, any time-stepping model duscribing a process(atmospheric processes, 3D circulation, 2D water level, sea surface temperature, soil systems, groundwater etc.). Presently, OpenDA features filtering techniques and calibration techniques. The presentation will give an overview of the OpenDA and the results of some of its practical applications. Application of data assimilation in portable operational forecasting systems—the DATools assimilation environment, El Serafy G.Y., H. Gerritsen, S. Hummel, A. H. Weerts, A.E. Mynett and M. Tanaka (2007), Journal of Ocean Dynamics, DOI 10.1007/s10236-007-0124-3, pp.485-499. COSTA a problem solving environment for data assimilation applied for hydrodynamical modelling, Van Velzen and Verlaan (2007), Meteorologische Zeitschrift, Volume 16, Number 6, December 2007 , pp. 777-793(17). Application of generic data assimilation tools (DATools) for flood forecasting purposes, A.H. Weerts, G.Y.H. El Serafy, S. Hummel, J. Dhondia, and H. Gerritsen (2009), accepted by Geoscience & Computers.

  20. Heparin Binds 8 kDa Gelsolin Cross-?-Sheet Oligomers and Accelerates Amyloidogenesis by Hastening Fibril Extension†

    PubMed Central

    Solomon, James P.; Bourgault, Steve; Powers, Evan T.; Kelly, Jeffery W.

    2011-01-01

    Glycosaminoglycans (GAGs) are highly sulfated linear polysaccharides prevalent in the extracellular matrix, and they associate with virtually all amyloid deposits in vivo. GAGs accelerate the aggregation of many amyloidogenic peptides in vitro, but little mechanistic evidence is available to explain why. Herein, spectroscopic methods demonstrate that GAGs do not affect the secondary structure of the monomeric 8 kDa amyloidogenic fragment of human plasma gelsolin. Moreover, monomerized 8 kDa gelsolin does not bind to heparin under physiological conditions. In contrast, 8 kDa gelsolin cross-?-sheet oligomers and amyloid fibrils bind strongly to heparin, apparently due to electrostatic interactions between the negatively charged polysaccharide and a positively charged region of the 8 kDa gelsolin assemblies. Our observations are consistent with a scaffolding mechanism, whereby cross-?-sheet oligomers, upon formation, bind to GAGs, accelerating the fibril extension phase of amyloidogenesis, possibly by concentrating and orienting the oligomers to more efficiently form amyloid fibrils. Notably, heparin decreases the 8 kDa gelsolin concentration necessary for amyloid fibril formation, likely a consequence of fibril stabilization through heparin binding. Since GAG overexpression, which is common in amyloidosis, may represent a strategy to minimize cross-?-sheet oligomer toxicity by transforming them into amyloid fibrils, the mechanism described herein for GAG-mediated acceleration of 8 kDa gelsolin amyloidogenesis provides a starting point for therapeutic strategy development. The addition of GAG mimetics, small molecule sulfonates shown to reduce the amyloid load in animal models of amyloidosis, to a heparin-accelerated 8 kDa gelsolin aggregation reaction neither significantly alters the rate of amyloidogenesis nor prevents oligomers from binding to GAGs, calling into question their commonly accepted mechanism. PMID:21348501

  1. Immune labeling and purification of a 71-kDa glutamate-binding protein from brain synaptic membranes

    SciTech Connect

    Chen, J.W.; Cunningham, M.D.; Galton, N.; Michaelis, E.K.

    1988-01-05

    Immunoblot studies of synaptic membranes isolated from rat brain using antibodies raised against a previously purified glutamate-binding protein (GBP) indicated labeling of an approx. 70-kDa protein band. Since the antibodies used were raised against a 14-kDa GBP, the present studies were undertaken to explore the possibility that the 14-kDa protein may have been a proteolytic fragment of a larger M/sub r/ protein in synaptic membranes. The major protein enriched in the most highly purified fractions was a 71-kDa glycoprotein, but a 63-kDa protein was co-purified during most steps of the isolation procedure. The glutamate-binding characteristics of these isolated protein fractions were very similar to those previously described for the 14-kDa GBP, including estimated dissociation constants for L-glutamate binding of 0.25 and 1 /sup +/M, inhibition of glutamate binding by azide and cyanide, and a selectivity of the ligand binding site for L-glutamate and L-aspartate. The neuroexcitatory analogs of L-glutamate and L-aspartate, ibotenate, quisqualate, and D-glutamate, inhibited L(/sup 3/H)glutamate binding to the isolated proteins, as did the antagonist of L-glutamate-induced neuronal excitation, L-glutamate diethylester. On the basis of the lack of any detectable glutamate-related enzyme activity associated with the isolated proteins and the presence of distinguishing sensitivities to analogs that inhibit glutamate transport carriers in synaptic membranes, it is proposed that the 71-kDa protein may be a component of a physiologic glutamate receptor complex in neuronal membranes.

  2. Nitrergic Pathway Is the Major Mechanism for the Effect of DA-9701 on the Rat Gastric Fundus Relaxation

    PubMed Central

    Min, Yang Won; Ko, Eun-ju; Lee, Ji Yeon; Min, Byung-Hoon; Lee, Jun Haeng; Kim, Jae J; Rhee, Poong-Lyul

    2014-01-01

    Background/Aims DA-9701 significantly improved gastric accommodation by increasing the postprandial gastric volume. In this study, we investigated how DA-9701 affects the rat gastric fundus relaxation. Methods Gastric fundus muscle strips (9 longitudinal and 7 circular muscles) were obtained from rats. Electrical field stimulation (EFS) was performed at various frequencies (1, 5, 10 and 20 Hz) and train durations (1, 5, 10 and 20 seconds) to select optimal condition for experiments. Isometric force measurements were performed in response to EFS. Peak and nadir were observed during the first 1 minute after initiation of EFS in control state and after sequential addition of atropine (1 ?M), DA-9701 (0.5, 5, 25 and 50 ?g), N-nitro-L-arginine (L-NNA, 100 ?M), MRS2500 (1 ?M) and tetrodotoxin (TTX, 1 ?M) to the organ bath. Results The optimal frequency and duration of EFS to evoke nerve-mediated relaxation was determined as 5 Hz for 10 seconds. Addition of L-NNA in the presence of atropine and DA-9701 (50 ?g) decreased nadir by inhibiting relaxation from ?0.054 ± 0.021 g to ?0.022 ± 0.015 g (P = 0.026) in longitudinal muscles. However, subsequent application of MRS2500 in the presence of atropine, DA-9701 (50 ?g) and L-NNA did not affect nadir. In circular muscles, subsequent addition of L-NNA and MRS2500 in the presence of atropine and DA-9701 (50 ?g) did not show significant change of nadir. Conclusions Our data suggest that the effect of DA-9701 on the rat gastric fundus relaxation is mainly mediated by nitrergic rather than purinergic pathway. PMID:24920748

  3. Projeto do sistema anti-ressonante da fiação dos transdutores para o detector Mario Schenberg

    NASA Astrophysics Data System (ADS)

    Vieira, S. J.., Jr.; Melo, J. L.

    2003-08-01

    O detector de ondas gravitacionais Mario Schenberg está sendo projetado e construído pelo grupo Gráviton. Sua construção está ocorrendo no Laboratório de Estado Sólido e Baixas Temperaturas (LESBT) da Universidade de São Paulo, na cidade de São Paulo. Esse detector possui uma massa ressonante esférica de cobre-alumínio, com 65 cm de diâmetro, pesando aproximadamente 1150 Kg, suspensa por um sistema de isolamento vibracional, que se encontra em fase de testes preliminares. A real eficácia desse sistema, entretanto, só poderá ser comprovada quando o detector estiver aparelhado com, pelo menos, um transdutor eletromecânico de altíssima sensibilidade acoplado à massa ressonante. Neste momento, não só este sistema de isolamento vibracional será posto em teste, como o do projeto da fiação que transporta os sinais de microondas até os transdutores e destes para a pré-amplificação. Apesar dessa fiação ter sido projetada para não apresentar nenhum contato com a superfície esférica da antena, de maneira a não haver nenhuma transmissão de ruído vibracional do laboratório para esta, deve-se minimizar o ruído microfônico produzido nessa fiação por oscilações mecânicas, uma vez que ela não utiliza nenhum sistema de isolamento vibracional. Com o intuito de resolver este problema, projetamos uma estrutura, formada por pequenos cilindros conectados por barras, a qual não terá nenhuma ressonância mecânica na faixa de freqüências de interesse para detecção (3000 - 3400 Hz). Desta forma, as vibrações nessa faixa não serão amplificadas. O projeto foi feito usando iterativamente, de maneira a otimizar os resultados obtidos, o programa de elementos finitos Msc/Nastran. Através de simulações feitas neste programa, determinamos os parâmetros geométricos ideais a serem utilizados, os quais proporcionam a maior região espectral de interesse livre de ressonâncias.

  4. [18 kDa translocator protein--implications in cell's functions].

    PubMed

    Ko?odziejczyk, Agnieszka

    2015-01-01

    The mitochondrial 18kDa Translocation Protein (TSPO) was first identified in 1977 by its capability to bind benzodiazepines in peripheral tissues. It is more commonly known after its previous name - peripheral benzodiazepine receptor (PBR) as opposed to the central benzodiazepine receptor (CBR), from which it differs by location, structure and function. It is ubiquitous with highest expression in steroid-producing tissues, like adrenal cortex, ovaries, testicles, and placenta. The role of TSPO is crucial for living; its inactivation results in early embryonic-lethal phenotype in mice. TSPO has been implicated in various functions of cell, including steroidogenesis, cellular respiration, reactive oxygen species production, heme biosynthesis, immunomodulation, apoptosis, and cellular proliferation. TSPO has been shown to interact with other cellular proteins: 32 kDa voltage-dependent anion channel (VDAC), 30 kDa adenine nucleotide translocase (ANT), cyclophilin D, hexokinase, creatinine kinase, diazepam binding inhibitor (DBI), phosphate carrier and Bcl-2 family. They are - involved in the formation and regulation of mitochondrial permeability transition pore (mPTP) at the junction of the inner and outer mitochondrial membranes. While the function and characteristics of the mPTP are known, its well defined, but its structure remains speculative. Changes in TSPO expression are associated with multiple disorders, including cancer, ischaemia-reperfusion injury, neurological diseases and psychiatric disorders, atheromatosis, and others. - TSPO is able to bind cholesterol, porphyrins and other ligands with different affinity. The current knowledge of TSPO implicates its potential use as a diagnostic marker and therapeutic target in different diseases and their therapies. PMID:25589712

  5. The stellar content of the Hamburg/ESO survey. I. Automated selection of DA white dwarfs

    E-print Network

    N. Christlieb; L. Wisotzki; D. Reimers; D. Homeier; D. Koester; U. Heber

    2000-11-24

    We describe automatic procedures for the selection of DA white dwarfs in the Hamburg/ESO objective-prism survey (HES). For this purpose, and the selection of other stellar objects (e.g., metal-poor stars and carbon stars), a flexible, robust algorithm for detection of stellar absorption and emission lines in the digital spectra of the HES was developed. Broad band (U-B, B-V) and narrow band (Str\\"omgren c_1) colours can be derived directly from HES spectra, with precisions of sigma(U-B)=0.092mag; sigma(B-V)=0.095mag; sigma(c_1)=0.15mag. We describe simulation techniques that allow to convert model or slit spectra to HES spectra. These simulated objective-prism spectra are used to determine quantitative selection criteria, and for the study of selection functions. We present an atlas of simulated HES spectra of DA and DB white dwarfs. Our current selection algorithm is tuned to yield maximum efficiency of the candidate sample (minimum contamination with non-DAs). DA candidates are selected in the B-V versus U-B and c_1 versus W_\\lambda(Hbeta+Hgamma+Hdelta) parameter spaces. The contamination of the resulting sample with hot subdwarfs is expected to be as low as ~8%, while there is essentially no contamination with main sequence or horizontal branch stars. We estimate that with the present set of criteria, ~80% of DAs present in the HES database are recovered. A yet higher degree of internal completeness could be reached at the expense of higher contamination. However, the external completeness is limited by additional losses caused by proper motion effects and the epoch differences between direct and spectral plates used in the HES.

  6. The Heliothis virescens 170 kDa aminopeptidase functions as “Receptor A” by mediating specific Bacillus thuringiensis Cry1A ?-endotoxin binding and pore formation

    Microsoft Academic Search

    Ke Luo; Sreedhara Sangadala; Luke Masson; Alberto Mazza; Roland Brousseau; Michael J Adang

    1997-01-01

    The relationship between Bacillus thuringiensis Cry1Aa, Cry1Ab and Cry1Ac ?-endotoxin binding and pore formation was investigated using a purified 170kDa aminopeptidase N (APN) from Heliothis virescens brush border membranes. Aminopeptidases with molecular sizes of 110, 140 and 170kDa were eluted from a Cry1Ac toxin affinity column using N-acetylgalactosamine. The 140kDa aminopeptidase has a cross-reacting determinant typical of a cleaved glycosyl-phosphatidylinositol

  7. Antibodies elicited by a virosomally formulated Plasmodium falciparum serine repeat antigen-5 derived peptide detect the processed 47 kDa fragment both in sporozoites and merozoites

    Microsoft Academic Search

    Shinji L. Okitsu; Francesca Boato; Markus S. Mueller; Dong Bo Li; Denise Vogel; Nicole Westerfeld; Rinaldo Zurbriggen; John A. Robinson; Gerd Pluschke

    2007-01-01

    Serine repeat antigen-5 (SERA5) is a candidate antigen for inclusion into a malaria subunit vaccine. During merozoite release and reinvasion the 120kDa SERA5 precursor protein (P120) is processed, and a complex consisting of an N-terminal 47kDa (P47) and a C-terminal 18kDa (P18) processing product associates with the surface of merozoites. This complex is thought to be involved in merozoite invasion

  8. HyDA-Vista: towards optimal guided selection of k-mer size for sequence assembly

    PubMed Central

    2014-01-01

    Motivation Intimately tied to assembly quality is the complexity of the de Bruijn graph built by the assembler. Thus, there have been many paradigms developed to decrease the complexity of the de Bruijn graph. One obvious combinatorial paradigm for this is to allow the value of k to vary; having a larger value of k where the graph is more complex and a smaller value of k where the graph would likely contain fewer spurious edges and vertices. One open problem that affects the practicality of this method is how to predict the value of k prior to building the de Bruijn graph. We show that optimal values of k can be predicted prior to assembly by using the information contained in a phylogenetically-close genome and therefore, help make the use of multiple values of k practical for genome assembly. Results We present HyDA-Vista, which is a genome assembler that uses homology information to choose a value of k for each read prior to the de Bruijn graph construction. The chosen k is optimal if there are no sequencing errors and the coverage is sufficient. Fundamental to our method is the construction of the maximal sequence landscape, which is a data structure that stores for each position in the input string, the largest repeated substring containing that position. In particular, we show the maximal sequence landscape can be constructed in O(n + n log n)-time and O(n)-space. HyDA-Vista first constructs the maximal sequence landscape for a homologous genome. The reads are then aligned to this reference genome, and values of k are assigned to each read using the maximal sequence landscape and the alignments. Eventually, all the reads are assembled by an iterative de Bruijn graph construction method. Our results and comparison to other assemblers demonstrate that HyDA-Vista achieves the best assembly of E. coli before repeat resolution or scaffolding. Availability HyDA-Vista is freely available [1]. The code for constructing the maximal sequence landscape and choosing the optimal value of k for each read is also separately available on the website and could be incorporated into any genome assembler. PMID:25558875

  9. Microfossils in micrites from Serra da Bodoquena (MS), Brazil: taxonomy and paleoenvironmental implications.

    PubMed

    Utida, Giselle; Petri, Setembrino; Oliveira, Emiliano C; Boggiani, Paulo C

    2012-06-01

    Microfossils present in Quaternary micrites from Serra da Bodoquena, Mato Grosso do Sul State, Brazil, are here described for the first time. The studied taxa are: a) ostracods: Candona sp., Candonopsis sp., Cyclocypris sp., Cypria sp., Cypridopsis sp., Notodromas sp., Ilyocypris sp., Cyprideis sp., Wolburgiopsis cf. chinamuertensis (Musacchio 1970), Darwinula sp. and 5 morphotypes; b) microgastropod Acrobis sp., and c) Characeae remains and gyrogonites Chara sp.. The presence of these microfossils suggests clear-water shallow lacustrine paleoenvironments and the presence of aquatic vegetation. Similarities between microfossils and the living taxa suggest possible Holocene ages for these deposits, which is in accordance with previous C(14) dates. PMID:22499261

  10. A Situação Social da Mulher no Teatro de Consuelo de Castro e Leilah Assunção

    E-print Network

    Barros, Alcides J. de.

    1976-04-01

    ver suas atrizes preferidas em ação. Muitas são as mulheres que se dedicam a essa atividade em caráter profissional, às vezes com invejável êxito. Não se pode, entretanto, dizer o mesmo com relação às autoras de textos teatrais, pois embora não haja... nenhuma objeção a que as mulheres escrevam para o teatro, são raríssimas as que o fazem, em com paração com os homens. De modo que quando surge uma peça escrita por uma mulher, o fato chama a atenção, independentemente da qualidade do texto. Con tudo...

  11. OCT structural examination of Madonna dei Fusi by Leonardo da Vinci

    NASA Astrophysics Data System (ADS)

    Targowski, Piotr; Iwanicka, Magdalena; Sylwestrzak, Marcin; Kaszewska, Ewa A.; Frosinini, Cecilia

    2013-05-01

    Madonna dei Fusi (`Madonna of the Yarnwider') is a spectacular example of Italian Renaissance painting, attributed to Leonardo da Vinci. The aim of this study is to give an account of past restoration procedures. The evidence of a former retouching campaign will be presented with cross-sectional images obtained non-invasively with Optical Coherence Tomography (OCT). Specifically, the locations of overpaintings/retouchings with respect to the original paint layer and secondary varnishes will be given. Additionally, the evidence of a former transfer of the pictorial layer to the new canvas support by detecting the presence of its structure incised into paint layer will be shown.

  12. Quadrupole Ion Mass Spectrometer for Masses of 2 to 50 Da

    NASA Technical Reports Server (NTRS)

    Helms, William; Griffin, Timothy P.; Ottens, Andrew; Harrison, Willard

    2005-01-01

    A customized quadrupole ion-trap mass spectrometer (QITMS) has been built to satisfy a need for a compact, rugged instrument for measuring small concentrations of hydrogen, helium, oxygen, and argon in a nitrogen atmosphere. This QITMS can also be used to perform quantitative analyses of other gases within its molecular-mass range, which is 2 to 50 daltons (Da). (More precisely, it can be used to perform quantitative analysis of gases that, when ionized, are characterized by m/Z ratios between 2 and 50, where m is the mass of an ion in daltons and Z is the number of fundamental electric charges on the ion.

  13. Measurement of the DA?NE luminosity with the KLOE detector using large angle Bhabha scattering

    NASA Astrophysics Data System (ADS)

    Ambrosino, F.; Antonelli, A.; Antonelli, M.; Bacci, C.; Beltrame, P.; Bencivenni, G.; Bertolucci, S.; Bini, C.; Bloise, C.; Bocci, V.; Bossi, F.; Bowring, D.; Branchini, P.; Caloi, R.; Campana, P.; Capon, G.; Capussela, T.; Ceradini, F.; Chi, S.; Chiefari, G.; Ciambrone, P.; Conetti, S.; De Lucia, E.; de Santis, A.; de Simone, P.; de Zorzi, G.; Dell'Agnello, S.; Denig, A.; di Domenico, A.; di Donato, C.; di Falco, S.; di Micco, B.; Doria, A.; Dreucci, M.; Felici, G.; Ferrari, A.; Ferrer, M. L.; Finocchiaro, G.; Fiore, S.; Forti, C.; Franzini, P.; Gatti, C.; Gauzzi, P.; Giovannella, S.; Gorini, E.; Graziani, E.; Incagli, M.; Kluge, W.; Kulikov, V.; Lacava, F.; Lanfranchi, G.; Lee-Franzini, J.; Leone, D.; Martini, M.; Massarotti, P.; Mei, W.; Meola, S.; Miscetti, S.; Moulson, M.; Müller, S.; Murtas, F.; Napolitano, M.; Nguyen, F.; Palutan, M.; Pasqualucci, E.; Passeri, A.; Patera, V.; Perfetto, F.; Pontecorvo, L.; Primavera, M.; Santangelo, P.; Santovetti, E.; Saracino, G.; Sciascia, B.; Sciubba, A.; Scuri, F.; Sfiligoi, I.; Spadaro, T.; Testa, M.; Tortora, L.; Valente, P.; Valeriani, B.; Venanzoni, G.; Veneziano, S.; Ventura, A.; Versaci, R.; Xu, G.

    2006-09-01

    We describe the method of measuring the integrated luminosity of the e+e- collider DA?NE, the Frascati ?-factory. The measurement is done with the KLOE detector selecting large angle Bhabha scattering events and normalizing them to the effective cross section. The e+e-?e+e-(?) cross section is calculated using different event generators which account for the mathcal{O}(?) radiative initial and final state corrections, and the ? resonance contribution. The accuracy of the measurement is 0.6%, where 0.3% comes from systematic errors related to the event counting and 0.5% from theoretical evaluations of the cross section.

  14. MA092 Geometria plana e analitica Comprimento da circunfer^encia -Area do circulo

    E-print Network

    Gomes, Francisco A. M.

    MA092 ­ Geometria plana e anal´itica Comprimento da circunfer^encia - ´Area do c´irculo Francisco A) 51.758 voltas Francisco A. M. Gomes (UNICAMP - IMECC)MA092 ­ Geometria plana e anal´itica Setembro de´itica Setembro de 2014 5 / 14 ´Area do c´irculo C´irculo ´Area A ´area de um c´irculo de raio R ´e dada por AC

  15. Pharmacological profile of DA-6886, a novel 5-HT4 receptor agonist to accelerate colonic motor activity in mice.

    PubMed

    Lee, Min Jung; Cho, Kang Hun; Park, Hyun Min; Sung, Hyun Jung; Choi, Sunghak; Im, Weonbin

    2014-07-15

    DA-6886, the gastrointestinal prokinetic benzamide derivative is a novel 5-HT4 receptor agonist being developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C). The purpose of this study was to characterize in vitro and in vivo pharmacological profile of DA-6886. We used various receptor binding assay, cAMP accumulation assay, organ bath experiment and colonic transit assay in normal and chemically constipated mice. DA-6886 exhibited high affinity and selectivity to human 5-HT4 receptor splice variants, with mean pKi of 7.1, 7.5, 7.9 for the human 5-HT4a, 5-HT4b and 5-HT4d, respectively. By contrast, DA-6886 did not show significant affinity for several receptors including dopamine D2 receptor, other 5-HT receptors except for 5-HT2B receptor (pKi value of 6.2). The affinity for 5-HT4 receptor was translated into functional agonist activity in Cos-7 cells expressing 5-HT4 receptor splice variants. Furthermore, DA-6886 induced relaxation of the rat oesophagus preparation (pEC50 value of 7.4) in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressing hERG channels revealed that it inhibited hERG channel current with an pIC50 value of 4.3, indicating that the compound was 1000-fold more selective for the 5-HT4 receptor over hERG channels. In the normal ICR mice, oral administration of DA-6886 (0.4 and 2mg/kg) resulted in marked stimulation of colonic transit. Furthermore, in the loperamide-induced constipation mouse model, 2mg/kg of DA-6886 significantly improved the delay of colonic transit, similar to 10mg/kg of tegaserod. Taken together, DA-6886 is a highly potent and selective 5-HT4 receptor agonist to accelerate colonic transit in mice, which might be therapeutic agent having a favorable safety profile in the treatment of gastrointestinal motor disorders such as IBS-C and chronic constipation. PMID:24769304

  16. Intracellular degradation of apolipoprotein B generates an N-terminal 70 kDa fragment in the endoplasmic reticulum.

    PubMed

    Sallach, S M; Adeli, K

    1995-02-16

    Regulated apoB degradation in HepG2 cells occurs in the endoplasmic reticulum (ER), is catalyzed by an N-acetylleucylleucylnorleucinal (ALLN)-sensitive proteinase, and generates a specific 70 kDa fragment (Adeli, K., 1994, J. Biol. Chem. 269, 9166-9175) [corrected]. In the present report, we have characterized the 70 kDa fragment by immunoprecipitation of permeabilized HepG2 cells with a battery of monoclonal antibodies against various sites on the apoB molecule. N-Terminal monoclonal antibodies (1D1 and 2D8) were capable of binding to the 70 kDa fragment suggesting that this polypeptide is an N-terminal fragment of the intact apoB. Subcellular fractionation of permeabilized cells and carbonate extraction resulted in the detection of the 70 kDa fragment in the ER lumen. Endoglycosidase H treatment confirmed that the fragment is N-linked glycosylated. We hypothesize that the ALLN-sensitive proteinase which may be located on the luminal side of the ER membrane, catalyzes an initial cleavage of apoB near the N-terminus generating a 70 kDa fragment, which is then released into the ER lumen. PMID:7857981

  17. Evaluating the potential of marine Bacteriovorax sp. DA5 as a biocontrol agent against vibriosis in Litopenaeus vannamei larvae.

    PubMed

    Wen, Chongqing; Xue, Ming; Liang, Huafang; Zhou, Shining

    2014-09-17

    The potential application of Bdellovibrio-and-like organisms (BALOs) for the biocontrol of bacterial diseases has been widely recognized. However, no marine BALOs have been reported for Vibrio-related infections in penaeid shrimp. In the present study, the bacteriolytic ability of the marine Bacteriovorax strain DA5 against Vibrio alginolyticus zouA was examined by cocultivation and electron microscopy, and optimal lysis was observed at 30-35°C and 20-30‰ salinity along with a high multiplicity of infection. Then, we showed that experimentally infected Litopenaeus vannamei larvae exhibited significantly higher survival with incremental DA5 levels. Finally, variation in the bacterial counts and the bacterial community in larval rearing water was investigated after prophylactic application of DA5. The elimination effect of DA5 on vibrios was visible at early time points, whereas only a few non-dominant bacteria, rather than the predominant populations, were affected through analysis of denaturing gradient gel electrophoresis of the 16S rDNA V3 region. Accordingly, the prophylactic and therapeutic efficacies of DA5 on vibriosis associated with L. vannamei could markedly enhance larval survivability, and these results will facilitate the application of marine Bacteriovorax to control vibriosis in shrimp larviculture. PMID:25139659

  18. PanDA: A New Paradigm for Distributed Computing in HEP Through the Lens of ATLAS and other Experiments

    E-print Network

    De, K; The ATLAS collaboration; Maeno, T; Nilsson, P; Wenaus, T

    2014-01-01

    Experiments at the Large Hadron Collider (LHC) face unprecedented computing challenges. Heterogeneous resources are distributed worldwide, thousands of physicists analyzing the data need remote access to hundreds of computing sites, the volume of processed data is beyond the exabyte scale, and data processing requires more than a billion hours of computing usage per year. The PanDA (Production and Distributed Analysis) system was developed to meet the scale and complexity of LHC distributed computing for the ATLAS experiment. In the process, the old batch job paradigm of computing in HEP was discarded in favor of a far more flexible and scalable model. The success of PanDA in ATLAS is leading to widespread adoption and testing by other experiments. PanDA is the first exascale workload management system in HEP, already operating at a million computing jobs per day, and processing over an exabyte of data in 2013. We will describe the design and implementation of PanDA, present data on the performance of PanDA a...

  19. Dual role of dextran sulfate 5000 Da as anti-apoptotic and pro-autophagy agent.

    PubMed

    Menvielle, J Pedro; Safini, Najete; Tisminetzky, Sergio G; Skoko, Natasa

    2013-06-01

    Dextran sulfate 5,000 Da (DS), a sulfated polysaccharide, has been used in recombinant mammalian cell cultures to prevent cell aggregation, thereby increasing cell viability. Previous studies using Chinese hamster ovary (CHO) suspension cultures had shown that low concentrations of DS are related to an inhibition of apoptosis. In this study, DS was used on anchorage-dependent CHO cells producing erythropoietin (EPO), in order to investigate the effect of this molecule on anti-apoptotic and pro-survival cellular pathways. DS 5,000 Da treatment was shown to prolong the life of cells and increase productivity of EPO by 1.8-fold comparing with controls, in standard batch conditions. At a molecular level, we show that DS inhibits apoptosis by DNA fragmentation delay and decrease of annexin V-labeled cells, causes a G0/G1 cell cycle arrest, decreases p53 expression and increases the pro-survival factor Hsc70 expression. DS treatment also resulted in an enhanced LC3-I to LC3-II conversion and increased autophagosomes formation employing tagged-LC3. Our data show, for the first time, that low doses of DS may promote autophagy in different cell lines. These findings suggest that a better understanding and manipulation of phenomenon of autophagy could be of crucial importance in the bio-pharmaceutical industry, in particular in the field of protein production. PMID:23180219

  20. A prologue on "Vastuguna Dipika". The Andhra Ayurv?da Nighantu of 1883 A.D.

    PubMed

    Rao, M Paramkusha; Khemani, Naresh

    2006-01-01

    Vastuguna Dipika is a Nighantu Grantha written in Telugu language on Ayurv?da drugs, diets and deeds in an alphabetical order in Telugu language and it is a much popular book for more than a century. Yerra Venkata Swamy (retired district Munsif) has authored and published it on 23rd June, 1883 A.D. It is a period of printing facility introduced in India. It is edited and reprinted eight times by the successors of same "Yerra" family during a period of century. The subject content of the book has been slowly updated from edition to edition. Vastuguna Dipika comprising of 1148 pages in written. Drug like Coffee, Cabbage have been elaborately dealt with Ayurv?da viewpoint. Certain drugs like Lasuna, Haridra also have been dealt very elaborately. In this book several drugs are grouped according to action and indications. Mineral drugs and mercurial preparations are also dealt in detail. Along with the properties of drugs and diet the properties and uses of certain routine deeds like bathing, sleeping exercise etc; are explained in the book. An alphabetical index of diseases in English in found along with the alphabetical indices of drugs in English, Telugu and Sanskrit languages. PMID:18175652

  1. Radiation tolerant D/A converters for the LHC cryogenic system

    NASA Astrophysics Data System (ADS)

    Franco, Francisco J.; Zong, Yi; de Agapito, Juan A.; Marques, José G.; Fernandes, Ana C.; Casas-Cubillos, Juan; Rodriguez-Ruiz, Miguel A.

    2005-11-01

    The electronic instrumentation of the Large Hadron Collider (LHC) cryogenic system is expected to receive a large radiation dose (>10 13 n cm -2 and 1-2 kGy (Si)) within 10 years of activity so all the electronic devices should tolerate this radiation level without a significant degradation. This paper focuses on the selection of a radiation tolerant 12-bit parallel input D/A converter suitable for the signal conditioners for cryogenic thermometry in the LHC. During an initial campaign, some candidate converters were irradiated to determine the most tolerant device. Once this was determined, a massive test was carried out. Some weak points of the selected device were addressed through the use of an external voltage source and a radiation tolerant operational amplifier. The tests show that a system consisting of an AD565 D/A converter, coupled to an external voltage reference and an OPA627 operational amplifier can tolerate a total radiation dose up to 5×10 13 n cm -2 and 2100 Gy (Si), thus satisfying the requirements set by CERN.

  2. PanDA: Exascale Federation of Resources for the ATLAS Experiment at the LHC

    E-print Network

    Barreiro Megino, Fernando Harald; The ATLAS collaboration; De, Kaushik; Hover, John; Klimentov, Alexei; Maeno, Tadashi; Nilsson, Paul; Oleynik, Danila; Padolski, Siarhei; Panitkin, Sergey; Petrosyan, Artem; Wenaus, Torre

    2015-01-01

    After a scheduled maintenance and upgrade period, the world’s largest and most powerful machine - the Large Hadron Collider(LHC) - is about to enter its second run at unprecedented energies. In order to exploit the scientific potential of the machine, the experiments at the LHC face computational challenges with enormous data volumes that need to be analysed by thousand of physics users and compared to simulated data. Given diverse funding constraints, the computational resources for the LHC have been deployed in a worldwide mesh of data centres, connected to each other through Grid technologies. The PanDA (Production and Distributed Analysis) system was developed in 2005 for the ATLAS experiment on top of this heterogeneous infrastructure to seamlessly integrate the computational resources and give the users the feeling of a unique system. Since its origins, PanDA has evolved together with upcoming computing paradigms in and outside HEP, such as changes in the networking model, Cloud Computing and HPC. It ...

  3. Monoclonal antibody to the gastrin receptor on parietal cells recognizes a 78-kDa protein

    SciTech Connect

    Mu, F.T.; Baldwin, G.; Weinstock, J.; Stockman, D.; Toh, B.H.

    1987-05-01

    Four monoclonal antibodies reactive by immunofluorescence and by flow microfluorimetry with canine and porcine gastric parietal cell membranes were produced by fusion of mouse NS-1 myeloma cells with splenocytes from mice immunized with a population of canine gastric mucosal cells containing 60-70% parietal cells. One of these, an IgM antibody designated 2Cl, reacted with the surface membranes of parietal cells by immunofluorescence, flow microfluorimetry, and immunogold electron microscopy; competed with /sup 125/I-labeled gastrin for binding to gastric cells; and inhibited by 56% maximal gastrin stimulation of (/sup 14/C)aminopyrine uptake in parietal cells. The antibody immunoprecipitated /sup 125/I-labeled samples of a 78-kDa gastrin-binding protein purified from membrane extracts of porcine gastrin mucosa but did not recognize the same protein labeled covalently with /sup 125/I-labeled gastrin-(2-17)-hexadecapeptide. These observations suggest that the previously identified 78-kDa gastrin-binding protein is the gastrin receptor and that the antibody 2C1 is directed against the gastrin binding site of the gastrin receptor.

  4. UniDA: uniform device access framework for human interaction environments.

    PubMed

    Varela, Gervasio; Paz-Lopez, Alejandro; Becerra, Jose Antonio; Vazquez-Rodriguez, Santiago; Duro, Richard José

    2011-01-01

    Human interaction environments (HIE) must be understood as any place where people carry out their daily life, including their work, family life, leisure and social life, interacting with technology to enhance or facilitate the experience. The integration of technology in these environments has been achieved in a disorderly and incompatible way, with devices operating in isolated islands with artificial edges delimited by the manufacturers. In this paper we are presenting the UniDA framework, an integral solution for the development of systems that require the integration and interoperation of devices and technologies in HIEs. It provides developers and installers with a uniform conceptual framework capable of modelling an HIE, together with a set of libraries, tools and devices to build distributed instrumentation networks with support for transparent integration of other technologies. A series of use case examples and a comparison to many of the existing technologies in the field has been included in order to show the benefits of using UniDA. PMID:22163700

  5. [Repercussions of the Maria da Penha law in tackling gender violence].

    PubMed

    Meneghel, Stela Nazareth; Mueller, Betânia; Collaziol, Marceli Emer; de Quadros, Maíra Meneghel

    2013-03-01

    This paper presents the declarations about the Maria da Penha law made by a sample of women victims and care workers who handle situations of gender violence in the city of Porto Alegre. The data are part of a study that investigated the critical path followed by women who decide to denounce violence. The statements were selected from 45 semi-structured interviews answered by 21 women and 25 professionals from the police, legal, social and health services and nongovernmental institutions. Data were analyzed using NVivo software and one of the categories selected was the Maria da Penha law. Most respondents mentioned the positive and innovatory aspects of the law, though they also pointed out its limitations. The care workers see the legal device as an important tool for tackling violence, aligned with international conventions, bringing innovations and broadening women's access to justice. In terms of weaknesses, both women and care workers stress the inefficiency in the implementation of protective measures, the lack of material resources and manpower, the fragmentation of the health care network and the movement of conservative sectors in society to delegitimize the law. PMID:23546196

  6. Photospheric phosphorus in the FUSE spectra of GD71 and two similar DA white dwarfs

    E-print Network

    Paul Dobbie; Martin Barstow; Ivan Hubeny; Jay Holberg; Matt Burleigh; Anne Forbes

    2005-07-27

    We report the detection, from FUSE data, of phosphorus in the atmospheres of GD71 and two similar DA white dwarfs. This is the first detection of a trace metal in the photosphere of the spectrophotometric standard star GD71. Collectively, these objects represent the coolest DA white dwarfs in which photospheric phosphorus has been observed. We use a grid of homogeneous non-LTE synthetic spectra to measure abundances of[P/H]=-8.57 +0.09 -0.13, -8.70 +0.23 -0.37 and -8.36 +0.14 -0.19 in GD71, RE J1918+595 and RE J0605-482 respectively. At the observed level we find phosphorus has no significant impact on the overall energy distribution of GD71. We explore possible mechanisms responsible for the presence of this element in these stars, concluding that the most likely is an interplay between radiative levitation and gravitational settling but possibly modified by weak mass loss.

  7. Volatile free fatty acids as ripening indicators for Serra da Estrela cheese.

    PubMed

    Tavaria, F K; Silva Ferreira, A C; Malcata, F Xavier

    2004-12-01

    Serra da Estrela cheese is an artisanal cheese manufactured from raw ewe's milk coagulated with Cynara cardunculus; it is highly appreciated for its unique flavor and bouquet. This research effort focused on a search for the molecules responsible for those organoleptic characteristics. Eighty cheeses manufactured in 4 dairies located in the Appelation d'Origine Protegee region of Serra da Estrela, Portugal, were thus assayed for volatiles, in an attempt to characterize their odorous profile. Cheeses were analyzed from the time of manufacture up to 180 d of ripening. The volatile fraction was assayed by solid phase microextraction-gas chromatography/mass spectroscopy, and several compounds belonging to different chemical groups (e.g., fatty acids, esters, carbonyl compounds, pyrazines, and sulfur compounds) were detected in that traditional cheese. Among these, free fatty acids (FFA) were quantitatively the dominant family present. Furthermore, sensory descriptors for the typical aroma of this cheese included acidic, sweaty, and sheepy-like. Acetic, isobutyric, and isovaleric acids increased in concentration during the ripening process up to 90 d, and remained constant thereafter. Preliminary sensory analysis was performed by addition of the major FFA to an unripened cheese matrix; results showed that they could successfully be used as ripening indicators for this cheese. Such key molecules may thus be used to monitor ripening, and hence find the optimal consumption time for this gourmet dairy product. PMID:15545367

  8. UniDA: Uniform Device Access Framework for Human Interaction Environments

    PubMed Central

    Varela, Gervasio; Paz-Lopez, Alejandro; Becerra, Jose Antonio; Vazquez-Rodriguez, Santiago; Duro, Richard José

    2011-01-01

    Human interaction environments (HIE) must be understood as any place where people carry out their daily life, including their work, family life, leisure and social life, interacting with technology to enhance or facilitate the experience. The integration of technology in these environments has been achieved in a disorderly and incompatible way, with devices operating in isolated islands with artificial edges delimited by the manufacturers. In this paper we are presenting the UniDA framework, an integral solution for the development of systems that require the integration and interoperation of devices and technologies in HIEs. It provides developers and installers with a uniform conceptual framework capable of modelling an HIE, together with a set of libraries, tools and devices to build distributed instrumentation networks with support for transparent integration of other technologies. A series of use case examples and a comparison to many of the existing technologies in the field has been included in order to show the benefits of using UniDA. PMID:22163700

  9. Evolution of DA white dwarfs in the context of a new theory of convection

    E-print Network

    L. G. Althaus; O. G. Benvenuto

    1998-12-02

    In this study we compute the structure and evolution of carbon-oxygen DA white dwarfs by means of a detailed and updated evolutionary code. We treat the energy transport by convection within the formalism of the full spectrum turbulence theory, as given by the Canuto, Goldman and Mazzitelli (CGM) model. We explore the effect of various hydrogen layer masses on both the surface gravity and the hydrogen burning. Convective mixing at low luminosities is also considered. One of our main interests in this work has been to study the evolution of ZZ Ceti models, with the aim of comparing the CGM and mixing length theory (MLT) predictions. In this connection, we find that the temperature profile given by the CGM model is markedly different from that of the ML1 and ML2 versions of MLT. We have also computed approximate effective temperatures for the theoretical blue edge of the DA instability strip by using thermal timescale arguments for our evolving models. In this context, we found that the CGM theory leads to blue edges that are cooler than the observed ones. However, because the determination of the atmospheric parameters of ZZ Ceti stars is dependent on the assumed convection description in model atmosphere calculation, observed blue edges computed considering the CGM theory are required in order to perform a sef consistent comparison of our results with observations. Finally, detailed pulsation calculations of ZZ Ceti models considering the CGM convection would be necessary to place the results found in this paper on a firmer basis.

  10. Characterization of a 19 kDa alpha-zein of high purity.

    PubMed

    Cabra, Vanessa; Arreguin, Roberto; Galvez, Amanda; Quirasco, Maricarmen; Vazquez-Duhalt, Rafael; Farres, Amelia

    2005-02-01

    A highly pure alpha-zein was extracted from corn flour using ethanol (95%). Subsequently, ion-exchange chromatography was performed, using SP-Sepharose that yielded a highly homogeneous protein. This protein migrated as a single band in 20% SDS-PAGE and in pH gradient gels, showing an isoelectric point of 6.8. Mass spectrometry (MALDI-TOF-MS) showed a single peak with a molecular mass of 24 535 Da. It was identified as Z19, when comparing the sequence obtained in an automatic Edman sequencer with the Swissprot database using BLAST. The molar extinction coefficient, determined by dry weight in 70% methanol, was 12 415.49 M(-1) cm(-1) at 280 nm. Light scattering showed its presence in a monodispersed state of 44-66 kDa aggregates in methanol (70%). Circular dichroism spectra allowed the estimation of an alpha-helix content that was lower than the one found for a mixture of two alpha-zeins but with a higher content of beta sheets. PMID:15686426

  11. Practical Aspects Of Forward And Reverse Energy Flow Spectroscopy Using The Bomem Da3 FT Spectrometer

    NASA Astrophysics Data System (ADS)

    Buijs, Henry L.; Zacharie, Abel

    1989-12-01

    In modern materials analysis it becomes increasingly important to analyze samples at temperatures different from ambient using a variety of analysis techniques. The analysis techniques can be separated into various classes such as 1) transmission 2) direct absorption via photo conductive measurements or reverse energy flow from a warmer detector to a cooler sample 3) reflection at near normal incidence or grazing angle and 4) emission, with particular emphasis on induced emission such as photo luminescence and Raman scattering. The Bomem DA3 FT spectrometer is particularly convenient for the interfacing of a variety of cryostats and other large accessories to the standard, two sample beam, front sample compartment and the new, greatly enlarged, rear sample compartment, which has two sequential sample focus positions. The DA3 now offers a convenient way to switch between sources of radiation and detector modules at the so called input side of the spectrometer. This avoids the need for moving the sample and its accessory, such as a cryostat, between the output side and the input side (emission port) of the spectrometer: all measurement techniques may be performed with the sample and accessory in one position. Operational details and results of measurements will be presented.

  12. Generation of a multi-band spectrum using a D/A converter for an RF-knockout system

    NASA Astrophysics Data System (ADS)

    Shinkai, Akio; Ishikawa, Soichiro; Nakanishi, Tetsuya

    2015-01-01

    A method of generating a multi-band spectrum is proposed using a digital-to-analog (D/A) converter. The multi-band spectrum is useful for the slow-beam-extraction from a synchrotron using the method of radio frequency (RF)-knockout. Data for the spectrum are calculated in advance to be saved in the memory of a D/A converter, and are output synchronized with external clocks. An experiment showed that a multi-band spectrum of 10 bands could be generated with a total bandwidth of about 16.4 MHz and each bandwidth less than 45 kHz. Beam simulation with this method showed that an RF signal from a D/A converter could be effectively used for the control of uniform spill structure.

  13. Identification of a 45-kDa protein at the protein import site of the yeast mitochondrial inner membrane.

    PubMed

    Scherer, P E; Manning-Krieg, U C; Jenö, P; Schatz, G; Horst, M

    1992-12-15

    Import of proteins into mitochondria involves the cooperation of protein translocation systems in the outer and inner membranes. We have identified a 45-kDa protein at the protein import site of the yeast mitochondrial inner membrane. This 45-kDa protein could be crosslinked to a partly translocated precursor, which cannot be imported across the inner membrane when the matrix is depleted of ATP. In addition, an antibody against this protein strongly inhibited protein import into right-side-out inner-membrane vesicles. The 45-kDa protein accounts for only 0.1% of mitochondrial protein and appears peripherally attached to the outer face of the inner membrane. The properties of this protein suggest that it is a component of the protein import system of the mitochondrial inner membrane. PMID:1465421

  14. Identification of a 45-kDa protein at the protein import site of the yeast mitochondrial inner membrane.

    PubMed Central

    Scherer, P E; Manning-Krieg, U C; Jenö, P; Schatz, G; Horst, M

    1992-01-01

    Import of proteins into mitochondria involves the cooperation of protein translocation systems in the outer and inner membranes. We have identified a 45-kDa protein at the protein import site of the yeast mitochondrial inner membrane. This 45-kDa protein could be crosslinked to a partly translocated precursor, which cannot be imported across the inner membrane when the matrix is depleted of ATP. In addition, an antibody against this protein strongly inhibited protein import into right-side-out inner-membrane vesicles. The 45-kDa protein accounts for only 0.1% of mitochondrial protein and appears peripherally attached to the outer face of the inner membrane. The properties of this protein suggest that it is a component of the protein import system of the mitochondrial inner membrane. Images PMID:1465421

  15. Purification and characteristics of a 30 kDa Cd-binding protein from rat testis cytosol

    SciTech Connect

    Kinoshita, C.M.

    1986-01-01

    The main objective of this dissertation was to purify the 30 kDa Cd-binding protein from rat testis cytosol (Cd-testin) in a form retaining 1 or more moles of Cd per mole of protein, following the addition of /sup 109/CdCl/sub 2/ to cytosol in amounts just sufficient to saturate the 30 kDa peak. Two successful procedures were developed based on (1) ammonium sulfate fractionation, hydrophobic interaction chromatography, and gel filtration; or (2) heat treatment (90/sup 0/C, 5 min) and gel filtration. Application of Method 1 to cytosol labeled with /sup 65/ZnCL/sub 2/ showed that Zn formed a complex analogous to Cd-testin. The Cd content (moles/mole protein) in two preparations of 30 kDa protein was 2.1 to 2.6 (Method 1); Method 2 gave more variable results (1.1 to 3.4). In neither case was a 30 kDa polypeptide detected by 20 SDS PAGE, but a major subunit (22 kDa/pl 4.6) was observed in both preparations, along with smaller subunits. Method 1 gave higher purity (3 spots) but lower yield (about 4% of cytosolic 30 kDa Cd) whereas Method 2 gave a much higher yield (about 45%) but somewhat lower purity based on 2D SDS PAGE. On the basis of these results, Cd-testin consists of subunits rather than a single polypeptide chain. It is concluded that rat testis contains novel proteins binding Cd or Zn, and can be isolated in forms that retain a high Cd content. The manner in which the Cd is bound, and the subunits involved, have not been determined.

  16. De novo sulfur SAD phasing of the lysosomal 66.3 kDa protein from mouse.

    PubMed

    Lakomek, Kristina; Dickmanns, Achim; Mueller, Uwe; Kollmann, Katrin; Deuschl, Florian; Berndt, Annette; Lübke, Torben; Ficner, Ralf

    2009-03-01

    The 66.3 kDa protein from mouse is a soluble protein of the lysosomal matrix. It is synthesized as a glycosylated 75 kDa preproprotein which is further processed into 28 and 40 kDa fragments. Despite bioinformatics approaches and molecular characterization of the 66.3 kDa protein, the mode of its maturation as well as its physiological function remained unknown. Therefore, it was decided to tackle this question by means of X-ray crystallography. After expression in a human fibrosarcoma cell line, the C-terminally His-tagged single-chain 66.3 kDa variant and the double-chain form consisting of a 28 kDa fragment and a 40 kDa fragment were purified to homogeneity but could not be separated during the purification procedure. This mixture was therefore used for crystallization. Single crystals were obtained and the structure of the 66.3 kDa protein was solved by means of sulfur SAD phasing using data collected at a wavelength of 1.9 A on the BESSY beamline BL14.2 of Freie Universität Berlin. Based on the anomalous signal, a 22-atom substructure comprising 21 intrinsic S atoms and one Xe atom with very low occupancy was found and refined at a resolution of 2.4 A using the programs SHELXC/D and SHARP. Density modification using SOLOMON and DM resulted in a high-quality electron-density map, enabling automatic model building with ARP/wARP. The initial model contained 85% of the amino-acid residues expected to be present in the asymmetric unit of the crystal. Subsequently, the model was completed and refined to an R(free) factor of 19.8%. The contribution of the single Xe atom to the anomalous signal was analyzed in comparison to that of the S atoms and was found to be negligible. This work should encourage the use of the weak anomalous scattering of intrinsic S atoms in SAD phasing, especially for proteins, which require both expensive and time-consuming expression and purification procedures, preventing extensive screening of heavy-atom crystal soaks. PMID:19237744

  17. Extracellular calmodulin-binding proteins in plants: purification of a 21-kDa calmodulin-binding protein

    Microsoft Academic Search

    Tang Jun; Wu Shupin; Bai Juan; Sun Daye

    1996-01-01

    A 21-kDa calmodulin (CaM)-binding protein and a 19-kDa calmodulin-binding protein were detected in 0.1 M CaCl2 extracts of Angelica dahurica L. suspension-cultured cells and carrot (Daucus carota L.) suspension-cultured cells, respectively, using a biotinylated cauliflower CaM gel-overlay technique in the presence of 1 mM Ca2+. No bands, or very weak bands, were shown on sodium dodecyl sulfate-polyacrylamide gel electrophoresis gels

  18. SOCIEDADE MISTRIO Voo da Malsia Numa altura em que o Homem lana sondas para cartografar o planeta Marte, ningum sabe ao certo onde

    E-print Network

    Instituto de Sistemas e Robotica

    planeta Marte, ninguém sabe ao certo onde se encontra o avião da Malaysia Airlines, com 239 pessoas semanas antes, chegaram de Marte no- vas imagens recolhidas pela sonda "Cu- riosity". Mas duas semanas Scott Hamilton, da con- #12;sultora de aviação americana Leeham. Ao contrário do que podem sugerir os

  19. UMA ANÁLISE DO PERFIL DOS CONSUMIDORES DE PRODUTOS ORGÂNICOS EM PERNAMBUCO: O CASO DA FEIRA AGRO-ECOLÓGICA CHICO MENDES –RECIFE- PE

    Microsoft Academic Search

    Ana Maria Navaes Da Silva; Jose De Lima Albuquerque; Demorval Dos Santos Filho; Renata Patricia Leandro Do Nascimento; Elizandro Souza Da Silva

    2008-01-01

    A agricultura orgânica vem se destacando como umas das alternativas ao modo de produção agrícola convencional, o qual não atende mais aos padrões de consumo atuais devido a um aumento da degradação do meio ambiente, da contaminação do solo e do próprio agricultor que se expõe aos venenos utilizados nos processos de produção. Com isso, a agricultura orgânica aparece vinculada

  20. Summa Phytopathol., Botucatu, v. 32, n. 3, p. 247-254, 2006 247 Incompatibilidade somtica em Rhizoctonia solani AG-1 IA da soja

    E-print Network

    McDonald, Bruce

    Rhizoctonia solani AG-1 IA da soja Ana Paula da Silva de Campos1 e Paulo Cezar Ceresini1, 2 1 Faculdade de/03/2006. ABSTRACT Rhizoctonia solani anastomosis group 1 IA (AG-1 IA) is considered one of the most important structure. RESUMO O fungo Rhizoctonia solani AG-1 IA é um dos patógenos mais importantes que afeta a cultura