Science.gov

Sample records for scientific publication pitfalls

  1. Pitfalls

    NASA Technical Reports Server (NTRS)

    Triffet, Terry

    1990-01-01

    Though potentially of great benefit to the nation, the experience of the workshop participants and their discussions with Sea Grant and Land Grant officials make it clear that the Space Grant Program must avoid certain pitfalls of the past and present if it is to be successful. The most important of these are listed and briefly discussed.

  2. Ethics and Scientific Publication

    ERIC Educational Resources Information Center

    Benos, Dale J.; Fabres, Jorge; Farmer, John; Gutierrez, Jessica P.; Hennessy, Kristin; Kosek, David; Lee, Joo Hyoung; Olteanu, Dragos; Russell, Tara; Wang, Kai

    2005-01-01

    This article summarizes the major categories of ethical violations encountered during submission, review, and publication of scientific articles. We discuss data fabrication and falsification, plagiarism, redundant and duplicate publication, conflict of interest, authorship, animal and human welfare, and reviewer responsibility. In each section,…

  3. Scientific publications in Nepal.

    PubMed

    Magar, A

    2012-09-01

    Scientific publications have become a mainstay of communication among readers, academicians, researchers and scientists worldwide. Although, its existence dates back to 17 th century in the West, Nepal is still struggling to take few steps towards improving its local science for last 50 years. Since the start of the first medical journal in 1963, the challenges remains as it were decades back regarding role of authors, peer reviewers, editors and even publishers in Nepal. Although, there has been some development in terms of the number of articles being published and appearances of the journals, yet there is a long way to go. This article analyzes the past and present scenario, and future perspective for scientific publications in Nepal. PMID:23281460

  4. Scientific Autonomy and Public Oversight

    PubMed Central

    Resnik, David B.

    2009-01-01

    When scientific research collides with social values, science’s right to self-governance becomes an issue of paramount concern. In this article, I develop an account of scientific autonomy within a framework of public oversight. I argue that scientific autonomy is justified because it promotes the progress of science, which benefits society, but that restrictions on autonomy can also be justified to prevent harm to people, society, or the environment, and to encourage beneficial research. I also distinguish between different ways of limiting scientific autonomy, and I argue that government involvement in scientific decision-making should usually occur through policies that control the process of science, rather than policies that control the content of science. PMID:19777124

  5. Accelerating scientific publication in biology.

    PubMed

    Vale, Ronald D

    2015-11-01

    Scientific publications enable results and ideas to be transmitted throughout the scientific community. The number and type of journal publications also have become the primary criteria used in evaluating career advancement. Our analysis suggests that publication practices have changed considerably in the life sciences over the past 30 years. More experimental data are now required for publication, and the average time required for graduate students to publish their first paper has increased and is approaching the desirable duration of PhD training. Because publication is generally a requirement for career progression, schemes to reduce the time of graduate student and postdoctoral training may be difficult to implement without also considering new mechanisms for accelerating communication of their work. The increasing time to publication also delays potential catalytic effects that ensue when many scientists have access to new information. The time has come for life scientists, funding agencies, and publishers to discuss how to communicate new findings in a way that best serves the interests of the public and the scientific community. PMID:26508643

  6. Accelerating scientific publication in biology

    PubMed Central

    Vale, Ronald D.

    2015-01-01

    Scientific publications enable results and ideas to be transmitted throughout the scientific community. The number and type of journal publications also have become the primary criteria used in evaluating career advancement. Our analysis suggests that publication practices have changed considerably in the life sciences over the past 30 years. More experimental data are now required for publication, and the average time required for graduate students to publish their first paper has increased and is approaching the desirable duration of PhD training. Because publication is generally a requirement for career progression, schemes to reduce the time of graduate student and postdoctoral training may be difficult to implement without also considering new mechanisms for accelerating communication of their work. The increasing time to publication also delays potential catalytic effects that ensue when many scientists have access to new information. The time has come for life scientists, funding agencies, and publishers to discuss how to communicate new findings in a way that best serves the interests of the public and the scientific community. PMID:26508643

  7. Going public: good scientific conduct.

    PubMed

    Meyer, Gitte; Sandøe, Peter

    2012-06-01

    The paper addresses issues of scientific conduct regarding relations between science and the media, relations between scientists and journalists, and attitudes towards the public at large. In the large and increasing body of literature on scientific conduct and misconduct, these issues seem underexposed as ethical challenges. Consequently, individual scientists here tend to be left alone with problems and dilemmas, with no guidance for good conduct. Ideas are presented about how to make up for this omission. Using a practical, ethical approach, the paper attempts to identify ways scientists might deal with ethical public relations issues, guided by a norm or maxim of openness. Drawing on and rethinking the CUDOS codification of the scientific ethos, as it was worked out by Robert K. Merton in 1942, we propose that this, which is echoed in current codifications of norms for good scientific conduct, contains a tacit maxim of openness which may naturally be extended to cover the public relations of science. Discussing openness as access, accountability, transparency and receptiveness, the argumentation concentrates on the possible prevention of misconduct with respect to, on the one hand, sins of omission-withholding important information from the public-and, on the other hand, abuses of the authority of science in order to gain publicity. Statements from interviews with scientists are used to illustrate how scientists might view the relevance of the issues raised. PMID:21088921

  8. Publication ethics and scientific misconduct.

    PubMed

    Peh, W C G; Ng, K H

    2010-12-01

    To maintain the readers' trust and to uphold the journal's reputation, it is paramount for the entire research, peer reviewer and publication process to follow ethical principles and decisions. Studies involving humans, animals, medical records and human tissues/organs need to be conducted ethically, and the appropriate approvals obtained. The privacy and confidentiality of patients, authors and reviewers should be respected. When required, rights and permissions should be sought. Common forms of scientific misconduct include misappropriation of ideas, violation of generally accepted research practices, failure to comply with legislative and regulatory requirements, falsification of data, and inappropriate behaviour in relation to misconduct. Authors can expect editorial action to be taken, should duplicate publication, plagiarism and other forms of scientific misconduct be attempted or detected. PMID:21221494

  9. Scientific Culture and Public Education

    NASA Astrophysics Data System (ADS)

    Cordero, Alberto

    Current science and science-friendly philosophy jointly yield a picture of the world and ourselves in it that is more substantial, detailed and coherent than any other produced before by natural philosophy. When carefully formulated this picture provides us with: (a) an unprecedentedly reliable representation of vast regions of the natural world; and (b) a non-arbitrary public framework for understanding and furthering important areas of public concern. This paper comments on the cultural and educational significance of this picture. Influential arguments against granting a privileged role to serious science on the basis of differential credibility are examined and found wanting. This result is then folded into an analysis of the significance of scientific thought and practice for a cautious conception of the goals and methods of public education.

  10. Public Access to Scientific Data and Publications

    NASA Astrophysics Data System (ADS)

    Barbier, L. M.; Bernstein, M.; Allen, G.

    2015-12-01

    NASA has developed a plan for complying with the OSTP requirement on public access to the results of scientific research - including both data and publications. NASA is establishing a single archive for public access to peer-reviewed publications following an appropriate embargo period. NASA has made a great effort to have data from its spacecraft openly available for many years. What is new is that now NASA will require scientists to submit -- at the time the research is proposed - a "data management plan". This plan will be evaluated along with the proposal during the review process. It is expected that the data used in peer-reviewed publications will be archived in a persistent format. Managing data for long-term storage will be a challenge as data volumes grow, formats and media evolve, and people are increasingly mobile. While we now have the capacity to store (cheaply) every bit of data we produce, that is certainly not the right strategy. In this talk, we will give a brief overview of how NASA interprets data publishing.

  11. Human brucellosis in South Africa: Public health and diagnostic pitfalls.

    PubMed

    Wojno, Justyna Maria; Moodley, Clinton; Pienaar, Jaco; Beylis, Natalie; Jacobsz, Lourens; Nicol, Mark P; Rossouw, Jenny; Bamford, Colleen

    2016-09-01

    Human brucellosis in South Africa (SA) is under-diagnosed and under-reported. This is because many clinicians have little or no experience in managing affected patients, and in part because of the nonspecific and insidious nature of the disease. A case of human brucellosis caused by Brucella melitensis in a patient from the Western Cape Province of SA is described, and the resulting exposure of staff members at two medical microbiology laboratories, as well as the public health investigation that was conducted, are discussed. This article aims to highlight the need for strengthening integration between public health, medical and veterinary services and exposing deficiencies in public health, veterinary and laboratory practices. PMID:27601111

  12. Scientific publication: An alternative career in physics

    NASA Astrophysics Data System (ADS)

    Ucko, Daniel

    2008-03-01

    Scientific research could not go forward without scientific dissemination and publication of research results. As a member of the editorial staff of Physical Review Letters, I hope to be able to shed some light on the nature of the role of APS journal editors in the publication process, what the job entails and field questions on this alternative career in science.

  13. Scientific publications: now a marketing decision?

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Scientists have been publishing in journals related to their disciplines. Now with the advent of the internet, many more options are now available and scientific publication has become a marketing decision. Scientific journals are rated by "impact factor" which is based on the average number of cita...

  14. Retractions of scientific publications: responsibility and accountability

    PubMed Central

    Katavić, Vedran

    2014-01-01

    This evidence-based opinion piece gives a short overview of the increase in retractions of publications in scientific journals and discusses various reasons for that increase. Also discussed are some of the recent prominent cases of scientific misconduct, the number of authors with multiple retractions, and problems with reproducibility of published research. Finally, some of the effects of faulty research on science and society, as well as possible solutions are discussed. PMID:24969915

  15. Acid Precipitation: Scientific Progress and Public Awareness.

    ERIC Educational Resources Information Center

    Cowling, Ellis B.

    1983-01-01

    Describes certain perspectives on scientific research and on the public debates about acid deposition and its effects. Although primary attention is given to European/North American research, the ideas developed are relevant in any world region sensitive to acid deposition resulting from intense industrialization. (Author/JN)

  16. Ethics of authorship in scientific publications

    PubMed Central

    Mandal, Jharna; Parija, Subhash Chandra

    2013-01-01

    Authorship should be based on the contribution provided by each author who has made a significant scientific contribution to a study. Credit of authorship has important academic, social and financial implications and is bound by guidelines, which aid in preserving transparency during writing and publication of research material so as to prevent violation of ethics. PMID:24470992

  17. Authorship in scientific publications: analysis and recommendations.

    PubMed

    Hess, Christian W; Brückner, Christian; Kaiser, Tony; Mauron, Alex; Wahli, Walter; Wenzel, Uwe Justus; Salathé, Michelle

    2015-01-01

    In 2008, a Swiss Academies of Arts and Sciences working group chaired by Professor Emilio Bossi issued a "Memorandum on scientific integrity and the handling of misconduct in the scientific context", together with a paper setting out principles and procedures concerning integrity in scientific research. In the Memorandum, unjustified claims of authorship in scientific publications are referred to as a form of scientific misconduct - a view widely shared in other countries. In the Principles and Procedures, the main criteria for legitimate authorship are specified, as well as the associated responsibilities. It is in fact not uncommon for disputes about authorship to arise with regard to publications in fields where research is generally conducted by teams rather than individuals. Such disputes may concern not only the question who is or is not to be listed as an author but also, frequently, the precise sequence of names, if the list is to reflect the various authors' roles and contributions. Subjective assessments of the contributions made by the individual members of a research group may differ substantially. As scientific collaboration - often across national boundaries - is now increasingly common, ensuring appropriate recognition of all parties is a complex matter and, where disagreements arise, it may not be easy to reach a consensus. In addition, customs have changed over the past few decades; for example, the practice of granting "honorary" authorship to an eminent researcher - formerly not unusual - is no longer considered acceptable. It should be borne in mind that the publications list has become by far the most important indicator of a researcher's scientific performance; for this reason, appropriate authorship credit has become a decisive factor in the careers of young researchers, and it needs to be managed and protected accordingly. At the international and national level, certain practices have therefore developed concerning the listing of authors

  18. Ranking of Cities According to Public Health Criteria: Pitfalls and Opportunities

    PubMed Central

    Ham, Sandra A.; Levin, Sarah; Zlot, Amy I.; Andrews, Richard R.; Miles, Rebecca

    2004-01-01

    Popular magazines often rank cities in terms of various aspects of quality of life. Such ranking studies can motivate people to visit or relocate to a particular city or increase the frequency with which they engage in healthy behaviors. With careful consideration of study design and data limitations, these efforts also can assist policymakers in identifying local public health issues. We discuss considerations in interpreting ranking studies that use environmental measures of a city population’s public health related to physical activity, nutrition, and obesity. Ranking studies such as those commonly publicized are constrained by statistical methodology issues and a lack of a scientific basis in regard to design. PMID:15053999

  19. Scientific disintegrity as a public bad.

    PubMed

    Engel, Christoph

    2015-05-01

    In this article, I argue that scientific dishonesty essentially results from an incentive problem; I do so using a standard economic model-the public bad. Arguably, at least in the short run, most scientists would increase their personal utility by being sloppy with scientific standards. Yet, if they do, it becomes more difficult for all scientists to make their voice heard in society, to convince policy makers to assign public funds to academia, and to lead fulfilling academic lives. The nature of the ensuing governance problem (and appropriate policy intervention) hinges on the definition of scientists' utility function. The policy problem is less grave if society attaches disproportionally more weight to severe or widespread violations and if individual scientists do not precisely know in advance when they will quit their academic lives. If most scientists internalize most scientific standards, then the problem is alleviated. However, internalization is immaterial if honorable scientists dislike that others advance their careers by violating those standards. Sanctions are helpful, even if relatively mild. However, it is important to also punish those who do not punish others for breaking the rules or, alternatively, to put some centralized mechanism for vigilance and enforcement into place. PMID:25987515

  20. Genetically Modified Plants: Public and Scientific Perceptions

    PubMed Central

    2013-01-01

    The potential of genetically modified plants to meet the requirements of growing population is not being recognized at present. This is a consequence of concerns raised by the public and the critics about their applications and release into the environment. These include effect on human health and environment, biosafety, world trade monopolies, trustworthiness of public institutions, integrity of regulatory agencies, loss of individual choice, and ethics as well as skepticism about the real potential of the genetically modified plants, and so on. Such concerns are enormous and prevalent even today. However, it should be acknowledged that most of them are not specific for genetically modified plants, and the public should not forget that the conventionally bred plants consumed by them are also associated with similar risks where no information about the gene(s) transfer is available. Moreover, most of the concerns are hypothetical and lack scientific background. Though a few concerns are still to be disproved, it is viewed that, with proper management, these genetically modified plants have immense potential for the betterment of mankind. In the present paper, an overview of the raised concerns and wherever possible reasons assigned to explain their intensity or unsuitability are reviewed. PMID:25937981

  1. Ranking scientific publications: the effect of nonlinearity

    NASA Astrophysics Data System (ADS)

    Yao, Liyang; Wei, Tian; Zeng, An; Fan, Ying; di, Zengru

    2014-10-01

    Ranking the significance of scientific publications is a long-standing challenge. The network-based analysis is a natural and common approach for evaluating the scientific credit of papers. Although the number of citations has been widely used as a metric to rank papers, recently some iterative processes such as the well-known PageRank algorithm have been applied to the citation networks to address this problem. In this paper, we introduce nonlinearity to the PageRank algorithm when aggregating resources from different nodes to further enhance the effect of important papers. The validation of our method is performed on the data of American Physical Society (APS) journals. The results indicate that the nonlinearity improves the performance of the PageRank algorithm in terms of ranking effectiveness, as well as robustness against malicious manipulations. Although the nonlinearity analysis is based on the PageRank algorithm, it can be easily extended to other iterative ranking algorithms and similar improvements are expected.

  2. Ranking scientific publications: the effect of nonlinearity

    PubMed Central

    Yao, Liyang; Wei, Tian; Zeng, An; Fan, Ying; Di, Zengru

    2014-01-01

    Ranking the significance of scientific publications is a long-standing challenge. The network-based analysis is a natural and common approach for evaluating the scientific credit of papers. Although the number of citations has been widely used as a metric to rank papers, recently some iterative processes such as the well-known PageRank algorithm have been applied to the citation networks to address this problem. In this paper, we introduce nonlinearity to the PageRank algorithm when aggregating resources from different nodes to further enhance the effect of important papers. The validation of our method is performed on the data of American Physical Society (APS) journals. The results indicate that the nonlinearity improves the performance of the PageRank algorithm in terms of ranking effectiveness, as well as robustness against malicious manipulations. Although the nonlinearity analysis is based on the PageRank algorithm, it can be easily extended to other iterative ranking algorithms and similar improvements are expected. PMID:25322852

  3. The spacelab scientific missions: A comprehensive bibliography of scientific publications

    NASA Technical Reports Server (NTRS)

    Torr, Marsha (Compiler)

    1995-01-01

    November 1993 represented the 10-year anniversary of the flight of Spacelab 1 mission, with the first precursor mission (OSTA-1) being launched 2 years earlier. Since that time, a total of 27 Shuttle missions has been flown, using the Spacelab system as a facility for conducting scientific research in space. The missions flown to date have allowed a total of approximately 500 Principle Investigator class investigations to be conducted in orbit. These investigations have constituted major scientific efforts in astronomy/astrophysics, atmospheric science, Earth observation, life sciences, microgravity science, and space plasma physics. An initial survey of the scientific products gleaned from Spacelab missions already flown was sent to the Principle Investigators. In that survey, information was gathered from the investigators on the scientific highlights of their investigations and statistical measurements of overall success -- such as papers published. This document is a compilation of the papers that have been published to date in referred literature.

  4. Positive Pitfalls

    ERIC Educational Resources Information Center

    Schneider, Michael

    2004-01-01

    This article describes how Cahokia middle and high school students conduct inquiry-based science through a pitfall trap experiment. In a collaborative effort, students designed and conducted pitfall trap investigations that combined their interest in the natural world with their love of technology. The students set up their own experiments to…

  5. Access to Scientific Publications: The Scientist's Perspective

    PubMed Central

    Voronin, Yegor; Myrzahmetov, Askar; Bernstein, Alan

    2011-01-01

    Background Scientific publishing is undergoing significant changes due to the growth of online publications, increases in the number of open access journals, and policies of funders and universities requiring authors to ensure that their publications become publicly accessible. Most studies of the impact of these changes have focused on the growth of articles available through open access or the number of open-access journals. Here, we investigated access to publications at a number of institutes and universities around the world, focusing on publications in HIV vaccine research – an area of biomedical research with special importance to the developing world. Methods and Findings We selected research papers in HIV vaccine research field, creating: 1) a first set of 50 most recently published papers with keywords “HIV vaccine” and 2) a second set of 200 articles randomly selected from those cited in the first set. Access to the majority (80%) of the recently published articles required subscription, while cited literature was much more accessible (67% freely available online). Subscriptions at a number of institutions around the world were assessed for providing access to subscription-only articles from the two sets. The access levels varied widely, ranging among institutions from 20% to 90%. Through the WHO-supported HINARI program, institutes in low-income countries had access comparable to that of institutes in the North. Finally, we examined the response rates for reprint requests sent to corresponding authors, a method commonly used before internet access became widespread. Contacting corresponding authors with requests for electronic copies of articles by email resulted in a 55-60% success rate, although in some cases it took up to 1.5 months to get a response. Conclusions While research articles are increasingly available on the internet in open access format, institutional subscriptions continue to play an important role. However, subscriptions do not

  6. Public understanding of science is not scientific literacy

    SciTech Connect

    McGowan, A.

    1995-12-31

    The author notes that public understanding of science has, in many quarters, been taken over by the wrong notion of scientific literacy. The need for the scientific community to develop the language that speaks to the public in general is explored. Methodologies to improve communication to the general public and increase their understanding with clearly developed metaphors are examined.

  7. [Increasing difficulties for scientific publication in Venezuela].

    PubMed

    Ryder, Elena

    2014-03-01

    A very important increase in the costs of the edition of scientific journals has taken place in Venezuela, due to difficulties in obtaining imported free acid paper and other materials used for handling documents. Like other journals, Investigaci6n Clinica has been considering switching completely to a digital publication format; however there are several reasons that prevent us to doing it at this time: the journal is distributed in printed form to many national institutions, which do not have immediate access to digital information. In addition, there exists a commitment of shipment of printed issues for some international indices and in exchange with other national and foreign journals, whose printed format we receive. Another important aspect is that our University maintains a weak technological platform that makes difficult the immediacy required for the interchange with authors and consulted referees of received papers; and there is a latent danger of limitations in the use of digital technologies, due to current national politic problems. Consequently, we need to continue with the printed format, but must reduce the amount of printed issues, so as not to limit the number of papers published in each edition. Nevertheless, there is an ever increasing number of contributions from foreign researches and Investigaci6n Clinica has been recently included in two new international indices, the SEIIC from Argentina and the Infobase Index from India, reasons that obligate us to maintain our levels of excellence and commitment to our authors and readers. PMID:24758096

  8. Publication pressure and scientific misconduct in medical scientists.

    PubMed

    Tijdink, Joeri K; Verbeke, Reinout; Smulders, Yvo M

    2014-12-01

    There is increasing evidence that scientific misconduct is more common than previously thought. Strong emphasis on scientific productivity may increase the sense of publication pressure. We administered a nationwide survey to Flemish biomedical scientists on whether they had engaged in scientific misconduct and whether they had experienced publication pressure. A total of 315 scientists participated in the survey; 15% of the respondents admitted they had fabricated, falsified, plagiarized, or manipulated data in the past 3 years. Fraud was more common among younger scientists working in a university hospital. Furthermore, 72% rated publication pressure as "too high." Publication pressure was strongly and significantly associated with a composite scientific misconduct severity score. PMID:25747691

  9. Chemistry, Scientific Thought, and Public Communication.

    ERIC Educational Resources Information Center

    Hermens, Richard A., Ed.

    1986-01-01

    Provides summaries of presentations given at a symposium organized at the 40th Northwest Regional Conference of the American Chemical Society. The participants addressed the role of scientists involved with educating the public, starting at the third-grade level, and continuing with high school, parents, citizen groups, and the general public. (TW)

  10. Writing Research Reports and Scholarly Manuscripts for Journal Publication: Pitfalls and Promises

    ERIC Educational Resources Information Center

    Harper, Frederick D.

    2006-01-01

    Valuable strategies and guidelines for preparing research reports and scholarly manuscripts for publication in refereed journals are presented with the primary aim of helping prospective authors gain acceptance of their manuscripts for publication. The discussion addresses issues such as developing the research idea or problem from a…

  11. The Citation Merit of Scientific Publications

    PubMed Central

    Crespo, Juan A.; Ortuño-Ortín, Ignacio; Ruiz-Castillo, Javier

    2012-01-01

    We propose a new method to assess the merit of any set of scientific papers in a given field based on the citations they receive. Given a field and a citation impact indicator, such as the mean citation or the -index, the merit of a given set of articles is identified with the probability that a randomly drawn set of articles from a given pool of articles in that field has a lower citation impact according to the indicator in question. The method allows for comparisons between sets of articles of different sizes and fields. Using a dataset acquired from Thomson Scientific that contains the articles published in the periodical literature in the period 1998–2007, we show that the novel approach yields rankings of research units different from those obtained by a direct application of the mean citation or the -index. PMID:23152867

  12. NASA scientific and technical publications: A catalog of special publications, reference publications, conference publications, and technical papers, 1987-1990

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This catalog lists 783 citations of all NASA Special Publications, NASA Reference Publications, NASA Conference Publications, and NASA Technical Papers that were entered into NASA Scientific and Technical Information Database during the year's 1987 through 1990. The entries are grouped by subject category. Indexes of subject terms, personal authors, and NASA report numbers are provided.

  13. NASA scientific and technical publications: A catalog of special publications, reference publications, conference publications, and technical papers, 1991-1992

    NASA Technical Reports Server (NTRS)

    1993-01-01

    This catalog lists 458 citations of all NASA Special Publications, NASA Reference Publications, NASA Conference Publications, and NASA Technical Papers that were entered into the NASA Scientific and Technical Information database during accession year 1991 through 1992. The entries are grouped by subject category. Indexes of subject terms, personal authors, and NASA report numbers are provided.

  14. NASA scientific and technical publications: A catalog of special publications, reference publications, conference publications, and technical papers, 1989

    NASA Technical Reports Server (NTRS)

    1990-01-01

    This catalog lists 190 citations of all NASA Special Publications, NASA Reference Publications, NASA Conference Publications, and NASA Technical Papers that were entered into the NASA scientific and technical information database during accession year 1989. The entries are grouped by subject category. Indexes of subject terms, personal authors, and NASA report numbers are provided.

  15. NASA scientific and technical publications: A catalog of Special Publications, Reference Publications, Conference Publications, and Technical Papers, 1987

    NASA Technical Reports Server (NTRS)

    1988-01-01

    This catalog lists 239 citations of all NASA Special Publications, NASA Reference Publications, NASA Conference Publications, and NASA Technical Papers that were entered in the NASA scientific and technical information database during accession year 1987. The entries are grouped by subject category. Indexes of subject terms, personal authors, and NASA report numbers are provided.

  16. Improving the Scientific Integrity of Nontechnical Publications

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Recent articles in Rangelands reveal two points about nontechnical publications of the Society for Rangeland Management: 1) the need for a rigorous peer-review process in publishing issue papers, and 2) the need to clearly separate peer-reviewed literature from editorial articles in Rangelands. The...

  17. Promises, Pitfalls, and Proposals: Automating Small Public Library Cataloging in a Consortium.

    ERIC Educational Resources Information Center

    Rioux, Margaret A.

    1991-01-01

    Discussion of issues that should be addressed when catalogers in small public libraries begin to automate as part of a consortium uses library cooperatives from Massachusetts (Cape Libraries Automated Materials Sharing, CLAMS) and Florida as examples. Topics discussed include characteristics of the catalogers; cataloging standards; decision…

  18. Knowledge or noise. Scientific publication and the electronic journal.

    PubMed

    McLeod, S D; Gieser, J P

    1996-10-01

    Over the last few years, the Internet has grown exponentially and is developing a role in the exchange of scientific information. However, a number of problematic issues are associated with electronic publications, including limited transmission speed, undependable file longevity, poorly documented postpublication editing, copyright infringement, and cultural impediments to acceptance. By measure of citation frequency, electronic journals seem to have limited influence within scientific discourse, but this medium is as yet in its infancy. Since electronic publication enjoys many potential advantages over traditional print publication, it is expected to gain far greater influence over time. The American Medical Association group of publications recognizes this and intends to develop its electronic publications with attention to maintaining traditional critical scientific standards. PMID:8859092

  19. Digital Format for Depositary Part of Scientific Publications' Collection

    NASA Astrophysics Data System (ADS)

    Zemskov, Andrei; Evstigneeva, Galina

    As a rule, any large library has so called depositary part of collection. Specific circulation of these publications is not high, but preservation, conservation and provision of access to given collection need permanent efforts. The paper presents evaluation of expenses and centralized systems efficiency. These systems (e.g. JSTOR, Backfiles for Future) are publicly accessible collections of full text versions of scientific periodicals.

  20. Politics and the erosion of federal scientific capacity: restoring scientific integrity to public health science.

    PubMed

    Rest, Kathleen M; Halpern, Michael H

    2007-11-01

    Our nation's health and prosperity are based on a foundation of independent scientific discovery. Yet in recent years, political interference in federal government science has become widespread, threatening this legacy. We explore the ways science has been misused, the attempts to measure the pervasiveness of this problem, and the effects on our long-term capacity to meet today's most complex public health challenges. Good government and a functioning democracy require public policy decisions to be informed by independent science. The scientific and public health communities must speak out to defend taxpayer-funded science from political interference. Encouragingly, both the scientific community and Congress are exploring ways to restore scientific integrity to federal policymaking. PMID:17901422

  1. Getting the Public Addicted to Scientific Data Through Social Media

    NASA Astrophysics Data System (ADS)

    Hasenkopf, C. A.; Flasher, J. C.; Lodoysamba, S.

    2013-12-01

    Effectively communicating about a scientific topic to the public can be challenging for scientists for a variety reasons that often boil down to an inadequate bridge between general knowledge and the specialized scientific knowledge needed to understand the context of what a scientist from a particular field wishes to convey. This issue makes it difficult for the public to interpret scientific information and leaves it vulnerable to misinterpretation and misrepresentation. Rather than 'dumb down' scientific information to the public, we believe the most effective way to bridge this gap is to provide a means for the public to have easy access to - and get addicted to! - the actual scientific data itself, presented in a straightforward form. To this end, we will discuss an air quality public awareness campaign that we launched in one of the most polluted cities in the world, Ulaanbaatar, Mongolia, over the past year. We have installed an air quality instrument at a university in Mongolia, and we automatically post data from the instrument on Facebook (UB Air Quality Info) and Twitter (@UB_Air). We provide infographics on how to understand the data, share relevant articles and local activities, and monitor the sites for questions from the public about the data. We also maintain a website that posts aggregate air quality information (http://ubdata.herokuapp.com) and publicly shares the code that automatically connects our air quality instrument to the social media sites. This social media project, the first of its kind in Mongolia, has been an effective way to provide: (1) a quantifiable context to the public about air pollution issues in Ulaanbaatar, (2) a forum for the public and decision makers - from ambassadors to politicians - to engage with experts in the field and each other, and (3) a device that helps prevent misrepresentation (or fabrication) of data for political ends. We will also discuss the broader utility of our project and possible application to other

  2. Lead and Cadmium in Public Health in Nigeria: Physicians Neglect and Pitfall in Patient Management

    PubMed Central

    Orisakwe, Orish Ebere

    2014-01-01

    Low-level heavy metals exposure may contribute much more toward the causation of chronic disease and impaired functioning than previously thought. Among the suggested preventive and intervention measures for the control of renal diseases are the reduction in the exposure to heavy metals. Although these indicate knowledge and awareness of possible role of some heavy metals in the etiogenesis of some chronic diseases by Nigerian Physicians, heavy metal assay as diagnostic guide in patient management is often omitted in most healthcare settings. This is a synoptic capture of the increased incidence and prevalence of some metabolic disorders where heavy metals may be implicated. A search of the terms heavy metal exposure, source, toxicity, metabolic disorders, poisoning in Nigeria, in bibliographical databases (in English language) such as PubMed, Scopus, Google Scholar, and Africa Journal Online (AJOL) digital library was conducted. Leaded gasoline, refuse dumping, absence of poison information centers, and poor record keeping characterize environmental health in Nigeria. Lead and cadmium are of most significant public health importance in Nigeria. The recognition and inclusion of heavy metals assays in the diagnosis of metabolic disorders may ensure early diagnosis and improve management. PMID:24696827

  3. The Scientific Basis for Law as a Public Health Tool

    PubMed Central

    Mercer, Shawna L.; Popovic, Tanja; Briss, Peter A.; Goodman, Richard A.; Thombley, Melisa L.; Hahn, Robert A.; Fox, Daniel M.

    2009-01-01

    Systematic reviews are generating valuable scientific knowledge about the impact of public health laws, but this knowledge is not readily accessible to policy makers. We identified 65 systematic reviews of studies on the effectiveness of 52 public health laws: 27 of those laws were found effective, 23 had insufficient evidence to judge effectiveness, 1 was harmful, and 1 was found to be ineffective. This is a valuable, scientific foundation—that uses the highest relevant standard of evidence—for the role of law as a public health tool. Additional primary studies and systematic reviews are needed to address significant gaps in knowledge about the laws’ public health impact, as are energetic, sustained initiatives to make the findings available to public policy makers. PMID:19008510

  4. Importance of scientific resources among local public health practitioners

    PubMed Central

    Fields, Robert P.; Stamatakis, Katherine A.; Duggan, Kathleen; Brownson, Ross C.

    2016-01-01

    Objectives This study examined the perceived importance of scientific resources for decision-making, among local health department (LHD) practitioners in the U.S. Methods This cross-sectional study used data from LHD practitioners (n=849). Respondents ranked important decision-making resources, methods for learning about public health research, and academic journal use. Descriptive statistics were calculated and logistic regression was used to measure associations of individual and LHD characteristics with importance of scientific resources. Results Systematic reviews of scientific literature (24.7%) was most frequently ranked as important among scientific resources, followed by scientific reports (15.9%), general literature review articles (6.5%), and one or a few scientific studies (4.8%). Graduate-level education (aORs ranging from 1.7 to 3.5), larger LHD size (aORs ranging from 2.0 to 3.5), and leadership support (aOR = 1.6; 95% confidence interval [CI] = 1.1, 2.3) were associated with a higher ranking of importance of scientific resources. Conclusions Graduate training, larger LHD size, and leadership that supports a culture of evidence-based decision-making may increase the likelihood of practitioners viewing scientific resources as important. Targeting communication channels that practitioners view as important can also guide research dissemination strategies. PMID:25689176

  5. [Financing of the scientific publication and protection of the scientific knowledge].

    PubMed

    Oliveira Filho, Renato Santos de; Hochman, Bernardo; Nahas, Fabio Xerfan; Ferreira, Lydia Masako

    2005-01-01

    The main purpose of a study is its publication on a scientific journal. Research financing agencies are important institutions so that studies can be developed and published. The most important research financing agencies that are discussed in this article are: "Coordenação de Aperfeiçoamento de Pessoal de Nível Superior" (CAPES), "Conselho Nacional de Desenvolvimento Científico e Tecnológico" (CNPq) and "Fundação de Amparo à Pesquisa do Estado de São Paulo" (FAPESP). CAPES' activities can be grouped in four different strategy lines: a) it evaluates the stricto sensu, at the post-graduation level; b) it provides access and development of scientific research; c) it provides investment on the development of high qualified human resources in Brazil and abroad, and d) it promotes international scientific cooperation. Although CAPES does not support directly scientific publications, almost all actions of this agency contribute to the development of scientific research and publication. CNPq has two main purposes: financing researches and development of human resources. It provides the researchers with financial aid to scientific publication. The grants for editing were specifically created for supporting the national scientific and technical publications edited by Brazilians institutions or societies. CNPq can also support Congresses, Symposiums and similar short-term courses. The Plataforma Lattes is also a branch of CNPq on which the Curriculum Lattes is available. This site has the curriculum vitae of the scientific community and is of great value for researchers. FAPESP also finances journal publications, articles and books that bring up original results of studies made by researchers from the state of São Paulo. It finances, partially, the travel expenses of innovative papers authors in meetings within the country or abroad. Brazilian authors are increasing the number of international publications. Universities, research institutes, financing agencies and

  6. The public's trust in scientific claims regarding offshore oil drilling.

    PubMed

    Carlisle, Juliet E; Feezell, Jessica T; Michaud, Kristy E H; Smith, Eric R A N; Smith, Leeanna

    2010-09-01

    Our study examines how individuals decide which scientific claims and experts to believe when faced with competing claims regarding a policy issue. Using an experiment in a public opinion survey, we test the source content and credibility hypotheses to assess how much confidence people have in reports about scientific studies of the safety of offshore oil drilling along the California coast. The results show that message content has a substantial impact. People tend to accept reports of scientific studies that support their values and prior beliefs, but not studies that contradict them. Previous studies have shown that core values influence message acceptance. We find that core values and prior beliefs have independent effects on message acceptance. We also find that the sources of the claims make little difference. Finally, the public leans toward believing reports that oil drilling is riskier than previously believed. PMID:21553598

  7. Media Coverage and Public Opinion on Scientific Controversies.

    ERIC Educational Resources Information Center

    Mazur, Allan

    1981-01-01

    Examines the relationship of media coverage and public opinion in scientific controversy. A survey of coverage of controversies arising regarding sociobiology, water fluoridation, nuclear power and the Three Mile Island disaster indicates that the media play an active role in shaping and constructing controversy rather than just reporting it. (JMF)

  8. A "Sense of Place" in Public Participation in Scientific Research

    ERIC Educational Resources Information Center

    Haywood, Benjamin K.

    2014-01-01

    Public participation in scientific research (PPSR) within the natural sciences has been demonstrated as an effective strategy to expand cognitive knowledge and understanding of ecology, with implications regarding individual perspectives, attitudes, and behaviors about the environment and feelings about the personal relevance of science. Yet the…

  9. Google Earth for Public Outreach Through Scientific Visualizations

    NASA Astrophysics Data System (ADS)

    Tuxen-Bettman, K.

    2008-12-01

    Google Earth Outreach helps non-profit and public benefit groups put their data online in a geographic context using Google Earth and Maps. This improves their outreach and communication with the world, and can effectively impact policy and public understanding of science. We will explore several exceptional examples that use Google Earth and Maps to display scientific data and share it with the world. You will learn what is necessary to get started on building your Earth or Maps application, which can allow your colleagues or the public to access, explore, and understand your data.

  10. 75 FR 60110 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ... AGENCY FIFRA Scientific Advisory Panel; Notice of Public Meeting AGENCY: Environmental Protection Agency..., Fungicide, and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review scientific... the scientific issues for this meeting. Nominees should be identified by name, occupation,...

  11. Fiction and scientific communication about volcanoes for the young public

    NASA Astrophysics Data System (ADS)

    Gaonach, H.; Drouin, V.

    2003-12-01

    Since January 2002, I have developed a new type of interactive web site for scientific news and communications about volcanic activities on the Earth and in our solar system. With the help of a small team (including an illustrator) based in GEOTOP at the University of Quebec in Montreal, I have created a monthly French language site on volcanoes including ongoing activity. Our multimedia site www.vickivolka.uqam.ca, combines open-style scientific news, including texts and pictures with scientific explanations. The originality lies in both the content and site structure. The monthly renewals inform the public on volcanic news but also on academic research and scientific experiments that young people can perform at home. We thus link breaking volcanic news with a deeper understanding of the processes and knowledge. Another original aspect is the use of fictional characters (Vicki and Anaky) who present the news and describe their adventures during the volcanic trips (volcanological, geographical, historic contents). Additional sections include interactive functions. Based on the success of this web site (published at the moment in French) - as evidenced notably by numerous primary school visits - we are planning to translate it in English very soon. This mixture of fiction with real world stories and scientific knowledge is an unusual effort by practising researchers and collaborators to strengthen links between the academic world and the general public, especially with children and educators.

  12. Roles for scientific societies in promoting integrity in publication ethics.

    PubMed

    Caelleigh, Addeane S

    2003-04-01

    Scientific societies can have a powerful influence on the professional lives of scientists. Using this influence, they have a responsibility to make long-term commitments and investments in promoting integrity in publication, just as in other areas of research ethics. Concepts that can inform the thinking and activities of scientific societies with regard to publication ethics are: the "hidden curriculum" (the message of actions rather than formal statements), a fresh look at the components of acting with integrity, deviancy as a normally occurring phenomenon in human society, and the scientific community as an actual community. A society's first step is to decide what values it will promote, within the framework of present-day standards of good conduct of science and given the society's history and traditions. The society then must create educational programs that serve members across their careers. Scientific societies must take seriously the implications of the problem; set policies and standards for publication ethics for their members; educate about and enforce the standards; bring the issues before the members early and often; and maintain continuing dialogue with editors. PMID:12774655

  13. Toolkit for evaluating impacts of public participation in scientific research

    NASA Astrophysics Data System (ADS)

    Bonney, R.; Phillips, T.

    2011-12-01

    The Toolkit for Evaluating Impacts of Public Participation in Scientific Research is being developed to meet a major need in the field of visitor studies: To provide project developers and other professionals, especially those with limited knowledge or understanding of evaluation techniques, with a systematic method for assessing project impact that facilitates longitudinal and cross-project comparisons. The need for the toolkit was first identified at the Citizen Science workshop held at the Cornell Lab of Ornithology in 2007 (McEver et al. 2007) and reaffirmed by a CAISE inquiry group that produced the recent report: "Public Participation in Scientific Research: Defining the Field and Assessing its Potential for Informal Science Education" (Bonney et al. 2009). This presentation will introduce the Toolkit, show how it is intended to be used, and describe ways that project directors can use their programmatic goals and use toolkit materials to outline a plan for evaluating the impacts of their project.

  14. 76 FR 47271 - Implementation of Scientific Integrity Principles: Draft Plan for Public Comment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-04

    ... Implementation of Scientific Integrity Principles: Draft Plan for Public Comment AGENCY: National Science Foundation. ACTION: National Science Foundation (NSF) Implementation of Scientific Integrity Principles... Heads of Executive Departments and Agencies on Scientific Integrity. Shortly thereafter the Office...

  15. 75 FR 51041 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ... AGENCY FIFRA Scientific Advisory Panel; Notice of Public Meeting AGENCY: Environmental Protection Agency..., and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review the Chlorpyrifos... the scientific issues for this meeting. Nominees should be identified by name, occupation,...

  16. 75 FR 76457 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-08

    ... AGENCY FIFRA Scientific Advisory Panel; Notice of Public Meeting AGENCY: Environmental Protection Agency... Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review the Chlorpyrifos Physiologically... the scientific issues for this meeting. Nominees should be identified by name, occupation,...

  17. 50 CFR 18.31 - Scientific research permits and public display permits.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Scientific research permits and public... Scientific research permits and public display permits. The Director may, upon receipt of an application and... importation of marine mammals for scientific research purposes or for public display. (a)...

  18. 50 CFR 18.31 - Scientific research permits and public display permits.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 8 2011-10-01 2011-10-01 false Scientific research permits and public... Scientific research permits and public display permits. The Director may, upon receipt of an application and... importation of marine mammals for scientific research purposes or for public display. (a)...

  19. 50 CFR 18.31 - Scientific research permits and public display permits.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 9 2012-10-01 2012-10-01 false Scientific research permits and public... Scientific research permits and public display permits. The Director may, upon receipt of an application and... importation of marine mammals for scientific research purposes or for public display. (a)...

  20. 50 CFR 18.31 - Scientific research permits and public display permits.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 9 2013-10-01 2013-10-01 false Scientific research permits and public... Scientific research permits and public display permits. The Director may, upon receipt of an application and... importation of marine mammals for scientific research purposes or for public display. (a)...

  1. 50 CFR 18.31 - Scientific research permits and public display permits.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 9 2014-10-01 2014-10-01 false Scientific research permits and public... Scientific research permits and public display permits. The Director may, upon receipt of an application and... importation of marine mammals for scientific research purposes or for public display. (a)...

  2. Scientific presentations and publications on odontological research in Argentina.

    PubMed

    Collet, A M; Piloni, M J; Keszler, A

    1997-01-01

    The results of odontological research which are presented at the annual meetings of the Argentine Division of the International Association for Dental Research (A.D.I.A.D.R.) are proof of the scientific production of this country in this area. An analysis of the presentations allows for the quantitative evaluation of the activity of the area. A deeper appraisal of the reality of research, involves the analysis of quality and publication efficiency. A useful indicator is the relationship between the quantity of the presentations and subsequent publications (Publ./Pres. Ratio) in Journals with peer review. In 1990, the authorities of the Division presented an evaluation of the 10 previous years (Acta Odont. Latinoamer. 7(2):39-46, 1993). The current Board of Directors has considered timely to update that information. With this aim in mind the presentations at A.D.I.A.D.R. over the period 1990-1995 were considered. Employing the authors index of the A.D.I.A.D.R. meeting we searched for possible publications in Medline. The references were compared with the data from the presentations, disregarding those which had not been communicated previously in the Division. The data obtained were grouped according to Research Center and subject area. The Publ./Pres. Ratio was calculated. The time to publication and language of publication were considered. Of a total of 506 presentations, 61 were published, Ratio Publ./Pres. 1:8 (12%). Considering each Center individually the ratio was 1:6 for the University of Buenos Aires (UBA), 1:13 for the National University of Córdoba (UNC), 1:3 for the National University of La Plata (UNLP) and 1:2 for the National University of Rosario (UNR). There were no records of publications from the National Universities of Tucumán and of the North-East. The groups of investigation with greater quantity of presentations and better Publ./Pres. Ratio were Dental Mat./Restorative Dent./Endod. (ratio 1:8), Physiol./Pharmacol./Biochem. (Ratio 1:4) and

  3. Misconduct accounts for the majority of retracted scientific publications

    PubMed Central

    Fang, Ferric C.; Steen, R. Grant; Casadevall, Arturo

    2012-01-01

    A detailed review of all 2,047 biomedical and life-science research articles indexed by PubMed as retracted on May 3, 2012 revealed that only 21.3% of retractions were attributable to error. In contrast, 67.4% of retractions were attributable to misconduct, including fraud or suspected fraud (43.4%), duplicate publication (14.2%), and plagiarism (9.8%). Incomplete, uninformative or misleading retraction announcements have led to a previous underestimation of the role of fraud in the ongoing retraction epidemic. The percentage of scientific articles retracted because of fraud has increased ∼10-fold since 1975. Retractions exhibit distinctive temporal and geographic patterns that may reveal underlying causes. PMID:23027971

  4. 76 FR 80417 - Request for Information: Public Access to Digital Data Resulting From Federally Funded Scientific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... Scientific Research ACTION: Notice of Request for Information (RFI). SUMMARY: The RFI is being extended to... federally funded scientific research. The public input provided through this Notice will inform... federally funded scientific research. The public input provided through this Notice will...

  5. 76 FR 68517 - Request for Information: Public Access to Digital Data Resulting From Federally Funded Scientific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-04

    ... Scientific Research ACTION: Notice of Request for Information (RFI). SUMMARY: In accordance with Section 103... unclassified digital data that result from federally funded scientific research. The public input provided... unclassified digital data that result from federally funded scientific research. The public input...

  6. 76 FR 55381 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-07

    ... AGENCY FIFRA Scientific Advisory Panel; Notice of Public Meeting AGENCY: Environmental Protection Agency..., and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review scientific... experience, to be capable of providing expert comments on the scientific issues for this meeting....

  7. 76 FR 46798 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ... AGENCY FIFRA Scientific Advisory Panel; Notice of Public Meeting AGENCY: Environmental Protection Agency..., Fungicide, and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review scientific... comments on the scientific issues for this meeting. Nominees should be identified by name,...

  8. 77 FR 8856 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-15

    ... AGENCY FIFRA Scientific Advisory Panel; Notice of Public Meeting AGENCY: Environmental Protection Agency..., and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review scientific issues... of providing expert comments on the scientific issues for this meeting. Nominees should be...

  9. 76 FR 26287 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-06

    ... AGENCY FIFRA Scientific Advisory Panel; Notice of Public Meeting AGENCY: Environmental Protection Agency..., and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review a set of scientific... training and experience, to be capable of providing expert comments on the scientific issues for...

  10. 75 FR 10255 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-05

    ... AGENCY FIFRA Scientific Advisory Panel; Notice of Public Meeting AGENCY: Environmental Protection Agency..., and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review a set of scientific... providing expert comments on the scientific issues for this meeting. Nominees should be identified by...

  11. Air pollution in China: Scientific and Public Policy Challenges

    NASA Astrophysics Data System (ADS)

    Zhu, T.

    2014-12-01

    Sever air pollution in China has in recent years caused intensive public, media and governmental attention. Many questions need to be answered about the air pollution in China, such as how harmful is the air pollution, especially PM2.5? Why suddenly so many reports about sever air pollution, is the air in China getting more polluted? How to design a policy that can control the air pollution most efficiently? After updated the national Ambient Air Quality Standards in 2012 and included PM2.5 as one of the critical air pollutants, in 2013, Chinese central government released for the first time the "Air Pollution Prevention and Control Action Plan". The plan has set goals to reduce annual mean concentration of PM2.5 up to 25% in 2017 in different regions in China. If the ambitious goals were achieved, this could be the most significant air pollution reduction in such a short time that affects so many people in human history. To achieve these goals, however, there are enormous scientific and public policy challenges to deal with. For example: Identify the key components, size fraction of PM that have the largest health effects; and identify the sources of PM that has the most harmful effects on human health and ecosystem. Reduce the uncertainty in health risk assessment. Understand complicate chemical transformation processes in air pollution formation with intensive emissions from industry, power plant, vehicles, agriculture. Interactions between air pollution, PBL, and atmospheric circulation at different scales. The accountability, feasibility, effectiveness, and efficiency of air pollution control policies. Integrate multi-pollutant control and achieve co-benefit with climate and energy policy. Regional coordinated air pollution control. The largest challenge in China for air pollution control remains how to strength the link between science and policy.

  12. Persistent data archives, data publication, authorship and scientific recognition (Invited)

    NASA Astrophysics Data System (ADS)

    Minster, J. H.

    2010-12-01

    Why don’t researchers get nearly as much credit for collecting and publishing high-quality data sets as they do for even a preliminary interpretation of data collected by themselves or by others? That does not seem fair! In the natural sciences, observations collected once can almost never be acquired again, nor can many experiments be repeated. These observations, therefore, are unique by definition, and hence might well become immensely valuable to future scientists. One would think, therefore that a premium should be placed on excellent data science, including peer-review, publication in secure, yet transparently accessible locations, commonly accepted citation standards, and full professional credit and recognition accorded to the practitioners. Technological options opened by today’s management, curation and on-line distribution of multi-disciplinary digital data sets make this an achievable goal. The new ICSU World Data System (WDS) is conceived as a global federated system of long-term data archives and data related services covering a wide spectrum of the sciences, and encouraging interdisciplinary science approaches. Because different disciplines (e.g. seismology, oceanography, astronomy, space sciences, biodiversity, health and social sciences) have developed domain-specific efficient answers to their own data challenges, WDS will by necessity evolve as a system of data systems. Nonetheless, certain overarching principles must be shared by all components: the main focus of WDS is on the long-term stewardship of scientific data (so that the value of data holdings might actually increase with time.) This calls, for instance, for the development and adoption of quality control practices, analysis and metadata services, and data publication services that can be recognized across domain boundaries. The latter will require a strong relationship with science publishers and libraries. Another focus point will be assisting scientists in developing a data

  13. 78 FR 66938 - Board of Scientific Counselors, Office of Public Health Preparedness and Response, Board of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... Public Health Preparedness and Response, Board of Scientific Counselors (BSC OPHPR) Cancellation This... More Information: Marquita Black, Executive Assistant, Office of Science and Public Health Practice... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  14. Public health care in Europe: moral aspirations, ideological obsessions, and structural pitfalls in a post-enlightenment culture.

    PubMed

    Azguridienė, Guoda; Delkeskamp-Hayes, Corinna

    2015-04-01

    This essay focuses on the challenge European states have imposed on themselves, namely, to provide state-of-the-art health care equally to all and for less than market price. Continued endorsement of that challenge in these states hinges on their character as media democracies: the public is moved by a supposed morally warranted expectation that all should receive adequate health care at no significant personal cost. The structural and economic constraints that hamper such forms of healthcare delivery result in systems that are financially inefficient and fail to provide the quality of treatment patients are led to expect. This essay examines the tension between secular moral claims to social solidarity and the actual limits of accessibility to healthcare services. Its critical focus addresses both the difficulties that result from politicians invoking high moral ideals while framing their decisions around short-term political advantage, and the transformation of the Enlightenment's secular aspirations into a political ideology that distorts such moral ideals. This essay concludes that the commitments to very particular notions of equality and human dignity, which frame contemporary Europe's provision of publicly subsidized health care, have given rise to a governance that is morally incoherent and unsustainable. This failure of public health care in Europe can thus be read as one more belated manifestation of the epistemological and moral failure of the Enlightenment's secularizing project, a failure which should invite contemporary Europeans to honestly face the moral challenge of postmodernity. PMID:25676731

  15. Automatic Extraction of Metadata from Scientific Publications for CRIS Systems

    ERIC Educational Resources Information Center

    Kovacevic, Aleksandar; Ivanovic, Dragan; Milosavljevic, Branko; Konjovic, Zora; Surla, Dusan

    2011-01-01

    Purpose: The aim of this paper is to develop a system for automatic extraction of metadata from scientific papers in PDF format for the information system for monitoring the scientific research activity of the University of Novi Sad (CRIS UNS). Design/methodology/approach: The system is based on machine learning and performs automatic extraction…

  16. 76 FR 16410 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-23

    ... AGENCY FIFRA Scientific Advisory Panel; Notice of Public Meeting AGENCY: Environmental Protection Agency..., Fungicide, and Rodenticide Act, Scientific Advisory Panel (FIFRA SAP) to consider and review a set of scientific issues related to Integrated Approaches to Testing and Assessment strategies (IATA): Use of...

  17. 78 FR 49750 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-15

    ... AGENCY FIFRA Scientific Advisory Panel; Notice of Public Meeting AGENCY: Environmental Protection Agency..., and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review RNAi Technology as a... comments on the scientific issues for this meeting. Nominees should be identified by name,...

  18. 76 FR 65722 - Notification of Two Public Teleconferences; Clean Air Scientific Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-24

    ... AGENCY Notification of Two Public Teleconferences; Clean Air Scientific Advisory Committee AGENCY... Clean Air Scientific Advisory Committee (CASAC) to discuss its draft review of EPA's Integrated Science... scientific and technical aspects of issues related to the criteria for air quality standards,...

  19. 77 FR 42307 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-18

    ... AGENCY FIFRA Scientific Advisory Panel; Notice of Public Meeting AGENCY: Environmental Protection Agency..., and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review the Pollinator Risk... comments on the scientific issues for this meeting. Nominees should be identified by name,...

  20. 78 FR 22873 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-17

    ... AGENCY FIFRA Scientific Advisory Panel; Notice of Public Meeting AGENCY: Environmental Protection Agency..., and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review Weight-of-Evidence... experience, to be capable of providing expert comments ] on the scientific issues for this meeting....

  1. 77 FR 20392 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-04

    ... AGENCY FIFRA Scientific Advisory Panel; Notice of Public Meeting AGENCY: Environmental Protection Agency..., and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review Problem Formulation... of providing expert comments on the scientific issues for this meeting. Nominees should be...

  2. 78 FR 12311 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-22

    ... AGENCY FIFRA Scientific Advisory Panel; Notice of Public Meeting AGENCY: Environmental Protection Agency..., and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review the Endocrine... comments on the scientific issues for this meeting. Nominees should be identified by name,...

  3. 76 FR 70176 - Request For Information: Public Access to Digital Data Resulting from Federally Funded Scientific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-10

    ... Scientific Research; Correction ACTION: Notice of Request for Information (RFI). SUMMARY: The RFI is being... public access to unclassified digital data that result from federally funded scientific research. The... research. The public input provided through this Notice will inform deliberations of the National...

  4. NASA's Plan for Improving Public Access to Federally Funded Scientific Research (Invited)

    NASA Astrophysics Data System (ADS)

    Allen, G.

    2013-12-01

    In February, 2013, OSTP issued a policy to all Federal agencies directing those that engage in $100 million or greater of federally funded research and development expenditures to develop an agency public access plan. The plan must consider both digital scientific data and scientific publications. This talk will review how NASA is currently complying with this OSTP directive, and NASA's plan for improving the public's ability to locate and access digital data and scientific publications resulting from NASA funded research. Updating NASA's policy will occur during FY 2014 and implementation of new policies and guidance will be in place by FY 2015.

  5. [Bad behaviors regarding research and scientific and medical publication].

    PubMed

    Sculier, J P

    2013-01-01

    Since a few years, the number of cases of fraud reported in the scientific and medical literature and retraction of articles has increased exponentially. Such fraud is due to fabrication, falsification, theft, embellishment or retention of data, plagiarism, incorrect list of authors or undisclosed conflicts of interest. This tendency has been explained by the need to publish for career advancement or the future of the department, the search for notoriety, the desire to grow rich and the lack of motivation to seek the truth. This crisis can be controlled by measures at different levels: society, universities, scientific institutions, study promoters, scientific and medical journals. A legal framework at EU level would allow to combat such fraud more efficiently. PMID:24505870

  6. 78 FR 40743 - Board of Scientific Counselors, Office of Public Health Preparedness and Response, Board of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-08

    ... Public Health Preparedness and Response, Board of Scientific Counselors (BSC OPHPR) In accordance with... Control and Prevention (CDC), and the Director, Office of Public Health Preparedness and Response (OPHPR... Address Contact Person for More Information: Marquita Black, Office of Science and Public Health...

  7. 76 FR 77235 - Board of Scientific Counselors, Office of Public Health Preparedness and Response: Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-12

    ... Public Health Preparedness and Response: Notice of Charter Renewal This gives notice under the Federal... of Public Health Preparedness and Response, Centers for Disease Control and Prevention (CDC... Scientific Counselors, Office of Public Health Preparedness and Response, CDC, HHS, 1600 Clifton Road...

  8. 78 FR 69682 - Board of Scientific Counselors, Office of Public Health Preparedness and Response: Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-20

    ... Public Health Preparedness and Response: Notice of Charter Renewal This gives notice under the Federal... of Public Health Preparedness and Response, Centers for Disease Control and Prevention (CDC... Scientific Counselors, Office of Public Health Preparedness and Response, CDC, HHS, 1600 Clifton Road,...

  9. The Reproduction of Scientific Understanding about Pendulum Motion in the Public

    NASA Astrophysics Data System (ADS)

    Manabu, Sumida

    This paper describes life-span development of understanding about pendulum motion and effects of school science. The subjects were 2,766 people ranging from kindergartners up to 88 years senior citizens. The conflict and consensus between children and their parent's understanding of pendulum motion were also analyzed. The kindergartner's understanding, mostly non-scientific, made a marked developmental change to another type of non-scientific understanding by the time they reach G 4. Parents with scientific understanding do not presumably nurture scientifically minded children,even though about half of them can apply scientific conceptions that shorter pendulums swing faster, and the amplitude and speed of pendulum motion do not depend on its weight. There seems to be another type of developmental change from scientific understanding to non-scientific understanding around their fifties. Itis suggested that the scientific understanding in the public about pendulum motion become predominant due to the educational intervention through school science.

  10. [First scientific research and publications on occupational medicine in Russia].

    PubMed

    Shigan, E E

    2016-01-01

    The article covers data on first in Russian Empire research works and publications on workers' health, occupation-related diseases occurrence, prevention and treatment of such diseases, prophylactic methods. PMID:27164753

  11. Self-correction in biomedical publications and the scientific impact

    PubMed Central

    Gasparyan, Armen Yuri; Ayvazyan, Lilit; Akazhanov, Nurbek A.; Kitas, George D.

    2014-01-01

    Aim To analyze mistakes and misconduct in multidisciplinary and specialized biomedical journals. Methods We conducted searches through PubMed to retrieve errata, duplicate, and retracted publications (as of January 30, 2014). To analyze publication activity and citation profiles of countries, multidisciplinary, and specialized biomedical journals, we referred to the latest data from the SCImago Journal & Country Rank database. Total number of indexed articles and values of the h-index of the fifty most productive countries and multidisciplinary journals were recorded and linked to the number of duplicate and retracted publications in PubMed. Results Our analysis found 2597 correction items. A striking increase in the number of corrections appeared in 2013, which is mainly due to 871 (85.3%) corrections from PLOS One. The number of duplicate publications was 1086. Articles frequently published in duplicate were reviews (15.6%), original studies (12.6%), and case reports (7.6%), whereas top three retracted articles were original studies (10.1%), randomized trials (8.8%), and reviews (7%). A strong association existed between the total number of publications across countries and duplicate (rs = 0.86, P < 0.001) and retracted items (rs = 0.812, P < 0.001). A similar trend was found between country-based h-index values and duplicate and retracted publications. Conclusion The study suggests that the intensified self-correction in biomedicine is due to the attention of readers and authors, who spot errors in their hub of evidence-based information. Digitization and open access confound the staggering increase in correction notices and retractions. PMID:24577829

  12. Mass Media and Global Warming: A Public Arenas Model of the Greenhouse Effect's Scientific Roots.

    ERIC Educational Resources Information Center

    Neuzil, Mark

    1995-01-01

    Uses the Public Arenas model to examine the historical roots of the greenhouse effect issue as communicated in scientific literature from the early 1800s to modern times. Utilizes a constructivist approach to discuss several possible explanations for the rise and fall of global warming as a social problem in the scientific arena. (PA)

  13. 78 FR 19705 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-02

    ... AGENCY FIFRA Scientific Advisory Panel; Notice of Public Meeting AGENCY: Environmental Protection Agency..., and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review proposed Endocrine... qualifications, including training and experience, to be capable of providing expert comments on the...

  14. 76 FR 54462 - Notification of a Public Teleconference; Clean Air Scientific Advisory Committee; Air Monitoring...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ... network in support of a newly revised National Ambient Air Quality Standard (NAAQS) for 1-hour NO 2 (75 FR... AGENCY Notification of a Public Teleconference; Clean Air Scientific Advisory Committee; Air Monitoring... teleconference of the Air Monitoring and Methods Subcommittee (AMMS) of the Clean Air Scientific...

  15. Seminar on Foci for Progress in Scientific Publications: A Summary and Final Report.

    ERIC Educational Resources Information Center

    Battelle Memorial Inst., Columbus, OH.

    A one-day seminar was convened on November 4, 1969, to consider problems involved in communicating scientific information and the progress that has been made in improving the scientific publication mechanism. Thirty participants representing different types of information producers, users, and organizations contributed to the seminar discussion.…

  16. Publication Bias ( The "File-Drawer Problem") in Scientific Inference

    NASA Technical Reports Server (NTRS)

    Scargle, Jeffrey D.; DeVincenzi, Donald (Technical Monitor)

    1999-01-01

    Publication bias arises whenever the probability that a study is published depends on the statistical significance of its results. This bias, often called the file-drawer effect since the unpublished results are imagined to be tucked away in researchers' file cabinets, is potentially a severe impediment to combining the statistical results of studies collected from the literature. With almost any reasonable quantitative model for publication bias, only a small number of studies lost in the file-drawer will produce a significant bias. This result contradicts the well known Fail Safe File Drawer (FSFD) method for setting limits on the potential harm of publication bias, widely used in social, medical and psychic research. This method incorrectly treats the file drawer as unbiased, and almost always miss-estimates the seriousness of publication bias. A large body of not only psychic research, but medical and social science studies, has mistakenly relied on this method to validate claimed discoveries. Statistical combination can be trusted only if it is known with certainty that all studies that have been carried out are included. Such certainty is virtually impossible to achieve in literature surveys.

  17. 42 CFR 82.33 - How will NIOSH inform the public of changes to the scientific elements underlying the dose...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... scientific elements underlying the dose reconstruction process? 82.33 Section 82.33 Public Health PUBLIC... ILLNESS COMPENSATION PROGRAM ACT OF 2000 Updating the Scientific Elements Underlying Dose Reconstructions § 82.33 How will NIOSH inform the public of changes to the scientific elements underlying the...

  18. 42 CFR 82.31 - How can the public recommend changes to scientific elements underlying the dose reconstruction...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false How can the public recommend changes to scientific... COMPENSATION PROGRAM ACT OF 2000 Updating the Scientific Elements Underlying Dose Reconstructions § 82.31 How can the public recommend changes to scientific elements underlying the dose reconstruction process?...

  19. 42 CFR 82.31 - How can the public recommend changes to scientific elements underlying the dose reconstruction...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false How can the public recommend changes to scientific... COMPENSATION PROGRAM ACT OF 2000 Updating the Scientific Elements Underlying Dose Reconstructions § 82.31 How can the public recommend changes to scientific elements underlying the dose reconstruction process?...

  20. 42 CFR 82.33 - How will NIOSH inform the public of changes to the scientific elements underlying the dose...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... scientific elements underlying the dose reconstruction process? 82.33 Section 82.33 Public Health PUBLIC... ILLNESS COMPENSATION PROGRAM ACT OF 2000 Updating the Scientific Elements Underlying Dose Reconstructions § 82.33 How will NIOSH inform the public of changes to the scientific elements underlying the...

  1. 42 CFR 82.31 - How can the public recommend changes to scientific elements underlying the dose reconstruction...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false How can the public recommend changes to scientific... COMPENSATION PROGRAM ACT OF 2000 Updating the Scientific Elements Underlying Dose Reconstructions § 82.31 How can the public recommend changes to scientific elements underlying the dose reconstruction process?...

  2. 42 CFR 82.33 - How will NIOSH inform the public of changes to the scientific elements underlying the dose...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... scientific elements underlying the dose reconstruction process? 82.33 Section 82.33 Public Health PUBLIC... ILLNESS COMPENSATION PROGRAM ACT OF 2000 Updating the Scientific Elements Underlying Dose Reconstructions § 82.33 How will NIOSH inform the public of changes to the scientific elements underlying the...

  3. 42 CFR 82.33 - How will NIOSH inform the public of changes to the scientific elements underlying the dose...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... scientific elements underlying the dose reconstruction process? 82.33 Section 82.33 Public Health PUBLIC... ILLNESS COMPENSATION PROGRAM ACT OF 2000 Updating the Scientific Elements Underlying Dose Reconstructions § 82.33 How will NIOSH inform the public of changes to the scientific elements underlying the...

  4. 42 CFR 82.31 - How can the public recommend changes to scientific elements underlying the dose reconstruction...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false How can the public recommend changes to scientific... COMPENSATION PROGRAM ACT OF 2000 Updating the Scientific Elements Underlying Dose Reconstructions § 82.31 How can the public recommend changes to scientific elements underlying the dose reconstruction process?...

  5. 42 CFR 82.33 - How will NIOSH inform the public of changes to the scientific elements underlying the dose...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... scientific elements underlying the dose reconstruction process? 82.33 Section 82.33 Public Health PUBLIC... ILLNESS COMPENSATION PROGRAM ACT OF 2000 Updating the Scientific Elements Underlying Dose Reconstructions § 82.33 How will NIOSH inform the public of changes to the scientific elements underlying the...

  6. 42 CFR 82.31 - How can the public recommend changes to scientific elements underlying the dose reconstruction...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false How can the public recommend changes to scientific... COMPENSATION PROGRAM ACT OF 2000 Updating the Scientific Elements Underlying Dose Reconstructions § 82.31 How can the public recommend changes to scientific elements underlying the dose reconstruction process?...

  7. Using Scientific Publications to Identify People with Similar Interests

    NASA Astrophysics Data System (ADS)

    Loh, Stanley; Lorenzi, Fabiana; Granada, Roger; Lichtnow, Daniel; Wives, Leandro Krug; Palazzo Moreira de Oliveira, José

    In many situations, related to some types of systems or organizations' tasks, it is necessary to identify people with similar profiles. In the case of a collaborative recommender system, items to be recommended are those associated to similar users. Another example, in the academic environment, is to identify new members to be part of a research group (people with similar profiles). This task of identifying people with similar profiles can be time-consuming. In this sense, this work considers that scientific papers written by people can be used to identify users with similar profiles. Considering this assumption, we have done some experiments to identify which parts of papers, which type of indexes (terms or concepts) and which type of similarity functions (Jaccard or a Fuzzy function) are more suitable to identify similar people. The paper presents the results of some experiments and some application scenarios considering academic environments.

  8. Using Astronomy to Promote a Scientific Culture in the Public

    NASA Astrophysics Data System (ADS)

    Alvarez, O.

    2009-05-01

    The new ``Planetario Habana'' Cultural Centre for Science and Technology under construction is a joint project between the Office of the Historian of the City of Havana and the Ministry of Science, Technology and Environment of Cuba. The whole centre will be aimed at guiding the interest towards basic sciences and astronomical formation of the people, in the most populated and frequented area of the country. A key objective of this project shall be serving as an instructive motivation and entertainment for the casual or habitual visitors to these facilities, offering them the possibility to enjoy vivid representations, play with interactive amusement equipments and listen to instructive presentations on astronomy and related sciences guided by qualified specialists, professors and outstanding university students. Another fundamental purpose shall be the establishment of a plan for educational complementation in coordination with schools in order to allow children and young people to participate in activities enabling them to get into the fascinating world of Astronomy, Exploration of Outer Space and Life as Cosmic Phenomenon. The setting up of the ``Planetario Habana'' Cultural Centre for Science and Technology will show in function the GOTO Planetarium G Cuba custom obtained under a Japanese Cultural Grant Aid. This centre shall develop into a nonpareil pole in the national environment for the scientific outreach and education of these sciences. Surrounded by the attractiveness of the colonial ``ambience'' of the Old Town of Havana, it shall become a centre for dissemination of information about new discoveries and scientific programs developed at national and international level. Here we present a general view of the project, its objectives, and its present and future development.

  9. Open semantic annotation of scientific publications using DOMEO

    PubMed Central

    2012-01-01

    Background Our group has developed a useful shared software framework for performing, versioning, sharing and viewing Web annotations of a number of kinds, using an open representation model. Methods The Domeo Annotation Tool was developed in tandem with this open model, the Annotation Ontology (AO). Development of both the Annotation Framework and the open model was driven by requirements of several different types of alpha users, including bench scientists and biomedical curators from university research labs, online scientific communities, publishing and pharmaceutical companies. Several use cases were incrementally implemented by the toolkit. These use cases in biomedical communications include personal note-taking, group document annotation, semantic tagging, claim-evidence-context extraction, reagent tagging, and curation of textmining results from entity extraction algorithms. Results We report on the Domeo user interface here. Domeo has been deployed in beta release as part of the NIH Neuroscience Information Framework (NIF, http://www.neuinfo.org) and is scheduled for production deployment in the NIF’s next full release. Future papers will describe other aspects of this work in detail, including Annotation Framework Services and components for integrating with external textmining services, such as the NCBO Annotator web service, and with other textmining applications using the Apache UIMA framework. PMID:22541592

  10. Offshore scientific and technical publications, February-July, Spring 1989. Quarterly report

    SciTech Connect

    Not Available

    1989-01-01

    The catalog lists all current (1987-1989) scientific and technical publications of the Offshore Minerals Management Program. The catalog is updated and released on a quarterly basis in winter, spring, summer, and fall. Publications available after July 21, 1989, will be listed in the next issue.

  11. Seven PC Purchasing Pitfalls.

    ERIC Educational Resources Information Center

    Wodarz, Nan

    1997-01-01

    Explores how to avoid common pitfalls when schools purchase computer equipment. Purchasing tips are provided in the areas of choosing multiple platforms, buying the cheapest model available, choosing a proprietary design, falling for untested technology, purchasing systems that are not upgradable, ignoring extended warranties, and failing to plan…

  12. PACS pitfalls and bottlenecks

    NASA Astrophysics Data System (ADS)

    Huang, H. K.; Lou, Shyhliang A.; Wong, Albert W. K.

    1997-05-01

    PACS pitfalls are mostly created from human error, whereas bottlenecks are due to imperfect design in either the PACS or image acquisition devices. These drawbacks can only be realized through accumulated clinical experience. Pitfalls due to human error are often initiated at imaging acquisition devices and at workstations. Three major errors at the acquisition devices are entering wrong input parameters, stopping an image transmission process improperly, and incorrect patient positioning. The error occurring most often at the workstation happens when the user enters too many key strokes or clicks the mouse too often before the workstation can respond. Other pitfalls at the workstation unrelated to human error are missing location markers in a CT or MR scout view, images displayed with unsuitable look-up-tables, and white boarders in CR images due to x-ray collimation. Pitfalls created due to human intervention can be minimized by a better quality assurance program and periodic in-service training, and by interfacing image acquisition devices to the HIS/RIS. Bottlenecks affecting the PACS operation include network contention; CR, CT, and MR images stacked up at acquisition devices; slow response from workstations; and long delays for image retrieval from the long term archive. Bottlenecks can be alleviated by improving the system architecture, re- configuring the networks, and streamlining operational procedures through a gradual understanding of the clinical environment. We have identified most of the pitfalls and bottlenecks discussed above in our hospital-integrated PACS based on the past two years of clinical experience. This paper categorizes some of these problems, illustrates their effect on PACS operations, and suggests methods for circumventing them.

  13. Ethics and Scientific Integrity in Public Health, Epidemiological and Clinical Research.

    PubMed

    Coughlin, Steven S; Barker, Amyre; Dawson, Angus

    2012-01-01

    The ethics and scientific integrity of biomedical and public health research requires that researchers behave in appropriate ways. However, this requires more than following of published research guidelines that seek to prevent scientific misconduct relating to serious deviations from widely accepted scientific norms for proposing, conducting, and reporting research (e.g., fabrication or falsification of research data or failures to report potential conflicts of interest). In this paper we argue for a broader account of scientific integrity, one consistent with that defended by the United States Institute of Medicine, involving a commitment to intellectual honesty and personal responsibility for one's actions as a researcher and to practices consistent with the responsible conduct of research and protection of the research participants. Maintaining high standards of ethical and scientific integrity helps to maintain public trust in the research enterprise. An increasing number of authors have pointed to the importance of mentoring and education in relation to the responsible conduct of science in preventing transgressions of scientific integrity. Just like in clinical research and biomedicine, epidemiologists and other public health researchers have the responsibility to exhibit and foster the very highest standards of scientific integrity. PMID:24532867

  14. Ethics and Scientific Integrity in Public Health, Epidemiological and Clinical Research

    PubMed Central

    Coughlin, Steven S.; Barker, Amyre; Dawson, Angus

    2012-01-01

    The ethics and scientific integrity of biomedical and public health research requires that researchers behave in appropriate ways. However, this requires more than following of published research guidelines that seek to prevent scientific misconduct relating to serious deviations from widely accepted scientific norms for proposing, conducting, and reporting research (e.g., fabrication or falsification of research data or failures to report potential conflicts of interest). In this paper we argue for a broader account of scientific integrity, one consistent with that defended by the United States Institute of Medicine, involving a commitment to intellectual honesty and personal responsibility for one’s actions as a researcher and to practices consistent with the responsible conduct of research and protection of the research participants. Maintaining high standards of ethical and scientific integrity helps to maintain public trust in the research enterprise. An increasing number of authors have pointed to the importance of mentoring and education in relation to the responsible conduct of science in preventing transgressions of scientific integrity. Just like in clinical research and biomedicine, epidemiologists and other public health researchers have the responsibility to exhibit and foster the very highest standards of scientific integrity. PMID:24532867

  15. Scientific publications in international anaesthesiology journals: a 10-year survey.

    PubMed

    Li, Z; Qiu, L-X; Wu, F-X; Yang, L-Q; Sun, S; Yu, W F

    2011-03-01

    Significant growth has been seen in the field of anaesthesiology in recent decades. The current geographic distribution of the publications on anaesthesia research may be different from ten years ago. We performed this literature survey to examine the national origin of articles published in international anaesthesiology journals and to evaluate their contribution to anaesthesia research. Articles published in 18 major anaesthesiology journals from 2000 to 2009 were identified from the PubMed database and the Science Citation Index. A total of 30,191 articles were published in the selected 18 journals from 2000 to 2009. The country responsible for the largest number of articles was the United States of America (29.4%), followed by the United Kingdom, Germany, Japan, Canada, Australia and France. Denmark, Switzerland and Finland had the largest number of articles per capita. Anesthesia & Analgesia published the most number of articles from 2000 to 2009, followed by Anesthesiology, Pain and the British Journal of Anaesthesia. The numbers of clinical studies and randomised controlled trials decreased markedly from 2000 to 2009. PMID:21485677

  16. Trusted Sources: The Role Scientific Societies Can Play in Improving Public Opinions on Climate Change

    NASA Astrophysics Data System (ADS)

    McEntee, C.; Cairns, A.; Buhrman, J.

    2012-12-01

    Public acceptance of the scientific consensus regarding climate change has eroded and misinformation designed to confuse the public is rapidly proliferating. Those issues, combined with an increase of politically motivated attacks on climate scientists and their research, have led to a place where ideology can trump scientific consensus as the foundation for developing policy solutions. The scientific community has been, thus far, unprepared to respond effectively to these developments. However, as a scientific society whose members engage in climate science research, and one whose organizational mission and vision are centered on the concepts of science for the benefit of humanity and ensuring a sustainable future, the American Geophysical Union can, and should, play an important role in reversing this trend. To that end, in 2011, AGU convened a Leadership Summit on Climate Science Communication, in which presidents, executive directors, and senior public policy staff from 17 scientific organizations engaged with experts in the social sciences regarding effective communication of climate science and with practitioners from agriculture, energy, and the military. The discussions focused on three key issues: the environment of climate science communication; public understanding of climate change; and the perspectives of consumers of climate science-based information who work with specific audiences. Participants diagnosed previous challenges and failings, enumerated the key constituencies that need to be effectively engaged, and identified the critical role played by cultural cognition—the influence of group values, particularly around equality and authority, individualism, and community; and the perceptions of risk. Since that meeting, AGU has consistently worked to identify and explore ways that it, and its members, and improve the effectiveness of their communication with the public about climate change. This presentation will focus on the insights AGU has

  17. Trends in scientific publications of Indian spine surgeons over 14 years (2000–2013)

    PubMed Central

    Kanna, Rishi Mugesh; Falavigna, Asdrubal; da Silva, Pedro Guarise; Quadros, Francine Wurzius; Merlin, Luiz Henrique; Radaelli, Lucas; Guyot, Juan Pablo; Dozza, Diego; Riew, Daniel K; Martins, Délio; Yoshiharu, Kawaguchi; Rajasekaran, S

    2016-01-01

    Background: The number and quality of scientific publications reflects the standards of scientific research in a country. However, the contribution of Indian spine surgeons toward global publications is unknown. The goal is to study the publications of Indian spine surgeons between 2000 and 2013. Materials and Methods: A literature search of the publications by Indian spine surgeons was performed using MEDLINE. The search terms used were India and several spine-related terminologies. The main information of the selected papers including the year of publication, scientific journal, type of pathology studied, Neurosurgical or Orthopedic Department where the study was done, type of study, and the type of article was analyzed. Results: A total of 4459 articles were identified using MEDLINE and after exclusion, 507 articles were analyzed. A growth of 440% in the number of publications was observed in the period between 2009 and 2013, during which 60.15% of the articles were published. Clinical studies (n = 492; 97.04) were the most common types of articles, followed by experimental studies and other types. The Neurosurgery department published the majority of the articles (58.2%). The three most common pathologies studied were spinal tumors (17.35%), surgical technique (15.4%), and spinal infection (15.2%). Conclusion: The current study shows that publications in the field of spine surgery have been increasing in the last few years, although it is less. Further efforts such as research training of spine surgeons, inducing collaborations and formulation of multicenter projects and periodically allocating adequate funds are key factors to improve the scientific publications from India. PMID:27293295

  18. Presenting a scientific paper, including the pitfalls.

    PubMed Central

    Lashford, L S

    1995-01-01

    The tone of the presentation is set with the writing of the abstract. Wanting a trip to Vienna is not a good enough reason for framing an abstract unless the data are really interesting. If you don't find them so, you can bet your life that nobody else will. Have you presented the work before? Increasingly, the forms inviting abstracts stipulate that they should contain novel data. This protects the audience from boredom and your reputation from the aspersion that you never have anything new to say. It has been my practice to communicate similar data at a second meeting provided it contains some new results and that it is targeted at a totally unrelated specialist group. Hopefully, no one will have heard the information before. However, it is not acceptable to simply rehash the same abstract but should reflect the special interests of the second group. If one genuinely wants the abstract accepted for oral presentation it must contain a clear hypothesis, a brief description of methods, an exposition of results, and a conclusion. That well worn phrase 'results will be presented' simply raises the suspicion that the author is hoping that the data will be ready by the time that the conference begins. Sometimes, in the rush to meet deadlines for abstract submission, the needs of coauthors are overlooked. This is a sensitive area and can easily temporarily wreck what appeared to be a harmonious collaboration. Do make sure that all coauthors have seen the abstract before submission and are happy with the content--it is good research practice and important to the smooth running of the research group. PMID:7574867

  19. Presenting a scientific paper, including the pitfalls.

    PubMed

    Lashford, L S

    1995-08-01

    The tone of the presentation is set with the writing of the abstract. Wanting a trip to Vienna is not a good enough reason for framing an abstract unless the data are really interesting. If you don't find them so, you can bet your life that nobody else will. Have you presented the work before? Increasingly, the forms inviting abstracts stipulate that they should contain novel data. This protects the audience from boredom and your reputation from the aspersion that you never have anything new to say. It has been my practice to communicate similar data at a second meeting provided it contains some new results and that it is targeted at a totally unrelated specialist group. Hopefully, no one will have heard the information before. However, it is not acceptable to simply rehash the same abstract but should reflect the special interests of the second group. If one genuinely wants the abstract accepted for oral presentation it must contain a clear hypothesis, a brief description of methods, an exposition of results, and a conclusion. That well worn phrase 'results will be presented' simply raises the suspicion that the author is hoping that the data will be ready by the time that the conference begins. Sometimes, in the rush to meet deadlines for abstract submission, the needs of coauthors are overlooked. This is a sensitive area and can easily temporarily wreck what appeared to be a harmonious collaboration. Do make sure that all coauthors have seen the abstract before submission and are happy with the content--it is good research practice and important to the smooth running of the research group. PMID:7574867

  20. [How to increase the visibility of your scientific publication on the Internet?].

    PubMed

    Maczuga, Justyna; Przyłuska, Jolanta

    2012-01-01

    New technologies compel the scientists to change their thinking about dissemination of their own publications. In the time of rapid information exchange scientific papers should be available to the largest possible audience, it is therefore of vital importance to prepare them properly. The authors present the ways how to optimize the visibility of scientific publications on the Internet by the use of appropriate choice of words in the title, summary and key words. They discuss the mechanisms of indexing in scientific search engines and bibliographic-abstract databases showing at the same time how to use them in drawing up the paper. They also give an example of two summaries of the same article. The first one comprises the elements of academic search engine optimization (ASEO) while the other one does not follow these principles in the article description. PMID:22994069

  1. The Role of Emotional Factors in Building Public Scientific Literacy and Engagement with Science

    NASA Astrophysics Data System (ADS)

    Lin, Huann-shyang; Hong, Zuway-R.; Huang, Tai-Chu

    2012-01-01

    This study uses the database from an extensive international study on 15-year-old students (N = 8,815) to analyze the relationship between emotional factors and students' scientific literacy and explore the potential link between the emotions of the students and subsequent public engagement with science. The results revealed that students' scientific literacy is significantly correlated with their interest, enjoyment, and engagement in science learning (p < 0.001). The groups of students with high levels of emotional factors outperform their medium- and low-level counterparts in scientific literacy. Additional comparisons of emotions during science learning between these students and the adult population from another study indicate a number of similarities with the exception that the adults are more involved in learning science through television. It is suggested that improving the emotions that current students experience when learning science is more likely to enhance future public engagement in science-related issues.

  2. The Role of Emotional Factors in Building Public Scientific Literacy and Engagement with Science

    ERIC Educational Resources Information Center

    Lin, Huann-shyang; Hong, Zuway-R.; Huang, Tai-Chu

    2012-01-01

    This study uses the database from an extensive international study on 15-year-old students (N = 8,815) to analyze the relationship between emotional factors and students' scientific literacy and explore the potential link between the emotions of the students and subsequent public engagement with science. The results revealed that students'…

  3. Media Violence and the American Public: Scientific Facts versus Media Misinformation.

    ERIC Educational Resources Information Center

    Bushman, Brad J.; Anderson, Craig A.

    2001-01-01

    Discusses how news coverage on the connections between media violence and aggression have left the public confused, examining whether media violence mirrors real world violence and how news reports about media violence and aggression have changed over time. Highlights the entertainment industry and scientific community, discussing why they often…

  4. 76 FR 66717 - Notification of a Public Teleconference of the Clean Air Scientific Advisory Committee Air...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-27

    ...The Environmental Protection Agency (EPA or Agency) Science Advisory Board (SAB) Staff Office announces a public teleconference of the Clean Air Scientific Advisory Committee (CASAC) Air Monitoring and Methods Subcommittee (AMMS) to discuss its draft report on EPA's draft Near-Road NO2 Monitoring Technical Assistance...

  5. Presenting Global Warming and Evolution as Public Health Issues to Encourage Acceptance of Scientific Evidence

    ERIC Educational Resources Information Center

    Stover, Shawn K.; McArthur, Laurence B.; Mabry, Michelle L.

    2013-01-01

    Although evidence supporting anthropogenic global warming and evolution by natural selection is considerable, the public does not embrace these concepts. The current study explores the hypothesis that individuals will become more receptive to scientific viewpoints if evidence for evolution and implications of global warming are presented as issues…

  6. English as an International Language of Scientific Publication: A Study of Attitudes

    ERIC Educational Resources Information Center

    Ferguson, Gibson; Perez-Llantada, Carmen; Plo, Ramon

    2011-01-01

    This paper focuses on an issue attracting increasing attention: the possible disadvantage inflicted on non-Anglophone academics by the dominance of English in scientific publication and academic exchange. We critically review the evidence for linguistic disadvantage, noting some of its limitations, and critique the native/non-native distinction as…

  7. Attitude of Indian dental professionals toward scientific publications: A questionnaire based study

    PubMed Central

    Verma, Pradhuman; Sachdeva, Suresh K.; Verma, Kanika Gupta; Khosa, Rameen; Basavraju, Suman; Dutta, Sanjay

    2015-01-01

    Background: Due to competitiveness and academic benefits, most dental professionals feel an urgent need to increase their publications. Hence, we explored the attitude of students and faculty members toward scientific publications through a questionnaire. Materials and Methods: A questionnaire consisting of 13 questions was sent by e-mails and posting the printed copies to dental postgraduate (PG) students (second and third year) and faculty members (n = 500 each). The returned completed questionnaires were analyzed. Results: About 37% of dental PG faculty and 35.6% PG students responded to the questionnaire, with overall response of 72.6%. Among the PG faculty, professors (P) had more scientific publications, followed by senior lecturers (SL) and readers (R). The publications as first or corresponding author were less among both faculty and PG students while co-authorship was more among PG students compared to faculty members. Awareness about the term “plagiarism” was overall high and relatively highest among R, followed by SL, P and PG students. The percentage of publications in fee charging journals was more among PG students than faculty members and self-funding for publication was observed in 86.4% of PG students and 94-100% among faculty members. Conclusion: About 72.6% of dental professionals were involved in publishing of their research work and the number of publications increased steadily with an increase in their academic experience. All the dental professionals concurred publications as the criteria for academic excellence. PMID:26604598

  8. Media violence and the American public. Scientific facts versus media misinformation.

    PubMed

    Bushman, B J; Anderson, C A

    2001-01-01

    Fifty years of news coverage on the link between media violence and aggression have left the U.S. public confused. Typical news articles pit researchers and child advocates against entertainment industry representatives, frequently giving equal weight to the arguments of both sides. A comparison of news reports and scientific knowledge about media effects reveals a disturbing discontinuity: Over the past 50 years, the average news report has changed from claims of a weak link to a moderate link and then back to a weak link between media violence and aggression. However, since 1975, the scientific confidence and statistical magnitude of this link have been clearly positive and have consistently increased over time. Reasons for this discontinuity between news reports and the actual state of scientific knowledge include the vested interests of the news, a misapplied fairness doctrine in news reporting, and the failure of the research community to effectively argue the scientific case. PMID:11413871

  9. The annotation and the usage of scientific databases could be improved with public issue tracker software

    PubMed Central

    Dall'Olio, Giovanni Marco; Bertranpetit, Jaume; Laayouni, Hafid

    2010-01-01

    Since the publication of their longtime predecessor The Atlas of Protein Sequences and Structures in 1965 by Margaret Dayhoff, scientific databases have become a key factor in the organization of modern science. All the information and knowledge described in the novel scientific literature is translated into entries in many different scientific databases, making it possible to obtain very accurate information on a biological entity like genes or proteins without having to manually review the literature on it. However, even for the databases with the finest annotation procedures, errors or unclear parts sometimes appear in the publicly released version and influence the research of unaware scientists using them. The researcher that finds an error in a database is often left in a uncertain state, and often abandons the effort of reporting it because of a lack of a standard procedure to do so. In the present work, we propose that the simple adoption of a public error tracker application, as in many open software projects, could improve the quality of the annotations in many databases and encourage feedback from the scientific community on the data annotated publicly. In order to illustrate the situation, we describe a series of errors that we found and helped solve on the genes of a very well-known pathway in various biomedically relevant databases. We would like to show that, even if a majority of the most important scientific databases have procedures for reporting errors, these are usually not publicly visible, making the process of reporting errors time consuming and not useful. Also, the effort made by the user that reports the error often goes unacknowledged, putting him in a discouraging position. PMID:21186182

  10. Bibliometric analysis of regional Latin America's scientific output in Public Health through SCImago Journal & Country Rank

    PubMed Central

    2014-01-01

    Background In the greater framework of the essential functions of Public Health, our focus is on a systematic, objective, external evaluation of Latin American scientific output, to compare its publications in the area of Public Health with those of other major geographic zones. We aim to describe the regional distribution of output in Public Health, and the level of visibility and specialization, for Latin America; it can then be characterized and compared in the international context. Methods The primary source of information was the Scopus database, using the category “Public Health, Environmental and Occupational Health”, in the period 1996–2011. Data were obtained through the portal of SCImago Journal and Country Rank. Using a set of qualitative (citation-based), quantitative (document recount) and collaborative (authors from more than one country) indicators, we derived complementary data. The methodology serves as an analytical tool for researchers and scientific policy-makers. Results The contribution of Latin America to the arsenal of world science lies more or less midway on the international scale in terms of its output and visibility. Revealed as its greatest strengths are the high level of specialization in Public Health and the sustained growth of output. The main limitations identified were a relative decrease in collaboration and low visibility. Conclusions Collaboration is a key factor behind the development of scientific activity in Latin America. Although this finding can be useful for formulating research policy in Latin American countries, it also underlines the need for further research into patterns of scientific communication in this region, to arrive at more specific recommendations. PMID:24950735

  11. Proposal Pitfalls Plaguing Researchers: Can Technical Communicators Make a Difference?

    ERIC Educational Resources Information Center

    Lemanski, Steve

    2014-01-01

    The facts bear out that the odds are against most scientific researchers and scholars--especially those just starting out--in their attempts to win funding for their research projects through their grant proposals. In this article, the author takes a close look at some of the proposal-related problems and pitfalls that have historically challenged…

  12. Economic analysis of scientific publications and implications for energy research and development

    NASA Astrophysics Data System (ADS)

    Popp, David

    2016-04-01

    The mix of public and private funding in alternative energy research makes isolating the effect of government funding challenging. Factors such as energy prices and environmental policy influence both private and public R&D decisions, and it may take several years for public R&D’s effect on technology to be realized. Here, by combining data on scientific publications for alternative energy technologies with data on government R&D support, I provide information on the lags between research funding and new publications and link these articles to citations in US energy patents. I find that US$1 million in additional government funding leads to one to two additional publications, but with lags as long as ten years between initial funding and publication. Finally, I show that adjustment costs associated with large increases in research funding are of little concern at current levels of public energy R&D support. These results suggest that there is room to expand public R&D budgets for renewable energy, but that the impact of any such expansion may not be realized for some time.

  13. Publication Ethics and the Emerging Scientific Workforce: Understanding ‘Plagiarism’ in a Global Context

    PubMed Central

    Cameron, Carrie; Zhao, Hui; McHugh, Michelle K.

    2013-01-01

    Scientific publication has long been dominated by the English language and is rapidly moving towards near complete hegemony of English, while the majority of the world’s publishing scientists are not native English speakers. This imbalance has important implications for training in and enforcement of publication ethics, particularly with respect to plagiarism. A lack of understanding of what constitutes plagiarism and the use of a linguistic support strategy known as patchwriting can lead to inadvertent misuse of source material by non-native speakers writing in English as well as to unfounded accusations of intentional scientific misconduct on the part of these authors. A rational and well-informed dialogue about this issue is needed among both native English speaking and non-native English speaking writers, editors, educators, and administrators. Recommendations for educating and training are provided. PMID:22104051

  14. [Scientific production in nutrition and the public perception of hunger and eating in Brazil].

    PubMed

    Coutinho, Marília; Lucatelli, Márcio

    2006-08-01

    There is a contradiction between the perceptions held by different sectors of the Establishment with regard to the questions of hunger and nutrition in Brazil. On the one hand, the flagship of the present Brazilian government's social policy is the "Fome Zero" program. This program is based on the notion that the condition of hunger is socially relevant in this country. On the other hand, the scientific community in the field of nutrition has, through epidemiological studies, highlighted obesity as one of the most serious public health problems in Brazil. The reason why the public perception is dissociated from the production of knowledge on this subject has old roots that are related to the difficulties in institutionalizing science in Brazil. This has been reflected in a relative lack of legitimacy for scientific discourse. The new factor in this situation is the attainment of greater international visibility by the scientific community in nutritional de epidemiology. The future of the practical application of the results from nutritional epidemiology research in Brazil depends on the dynamics of the political agenda regarding hunger and nutrition, and of the sectors associated with this. The objective of this study was to explore this situation by means of analyzing scientometric data on the scientific production, historical data and documents relating to discourse about hunger. PMID:16924308

  15. Persistent Identifiers in the Publication and Citation of Scientific Data - Theory and Practice

    NASA Astrophysics Data System (ADS)

    Klump, J.; Brase, J.; Diepenbroek, M.; Grobe, H.; Hildenbrand, B.; Hoeck, H.; Lautenschlager, M.; Sens, I.

    2008-12-01

    In the last decade data driven research has become a third pillar of scientific work alongside with theoretical reasoning and experiment. Greatly increased computing power and storage, together with web services and other electronic resources have facilitated a quantum leap in new research based on the analysis of great amounts of data. However, traditional scientific communication only slowly changes to new media other than an emulation of paper. This leaves many data inaccessible and, in the long run exposes valuable data to the risk of loss. To improve access to data and to create incentives for scientists to make their data accessible, a group of German data centres initiated the project "Publication and Citation of Scientific Data" (STD-DOI) which was funded by the German Science Foundation DFG for the periods 2003-2005 and 2006-2008. In this project the German National Library for Science and Technology (TIB Hannover), together with the German Research Centre for Geoscience (GFZ Potsdam), Alfred Wegener Institute for Polar and Marine Research (AWI) Bremerhaven, University of Bremen, the Max Planck Institute for Meteorology in Hamburg, and the DLR German Remote Sensing Data Center set up the first system to assign DOIs to data sets and for their publication. A prerequisite for data to be made available is a proper citation. This means that all fields mandatory for a bibliographic citation are included. In addition, a mechanism is needed that ensures that the location of the referenced data on the internet can be resolved at any time. In the past, this was a problematic issue because URLs are short-lived, many becoming invalid after only a few months. Data publication on the internet therefore needs a system of reliable pointers to a web publication to make these publications citeable. To achieve this persistence of identifiers for their conventional publications many scientific publishers use Digital Object Identifiers (DOI). The identifier is resolved through

  16. Open access and openly accessible: a study of scientific publications shared via the internet

    PubMed Central

    Wren, Jonathan D

    2005-01-01

    Objectives To determine how often reprints of scientific publications are shared online, whether journal readership level is a predictor, how the amount of file sharing changes with the age of the article, and to what degree open access publications are shared on non-journal websites. Design The internet was searched using an application programming interface to Google, a popular and freely available search engine. Main outcome measures The proportion of reprints of journal articles published between 1994 and 2004 from within 13 subscription based and four open access journals that could be located online at non-journal websites. Results The probability that an article could be found online at a non-journal website correlated with the journal impact factor and the time since initial publication. Papers from higher impact journals and more recent articles were more likely to be located. On average, for the high impact journal articles published in 2003, over a third could be located at non-journal websites. Similar trends were observed for the delayed or full open access publications. Conclusions Decentralised sharing of scientific reprints through the internet creates a degree of de facto open access that, though highly incomplete in its coverage, is none the less biased towards publications of higher popular demand. PMID:15827063

  17. A scientific impact indicator based on the latent ``citability'' of a researcher's publications

    NASA Astrophysics Data System (ADS)

    Moreira, Joao; Zeng, Xiaohan; Amaral, Luis

    2014-03-01

    How to quantify the impact of a scientist's body of work is currently a matter of great concern. The use of bibliometric indicators, such as the h-index or the Journal Impact Factor, have become widespread despite their known limitations. We surmise that many of the deficiencies of existing bibliometric indicators arise from their heuristic nature. Here, we pursue a principled approach to the development of an indicator to quantify the scientific impact of individual researchers, grounded on the functional form of the distribution of the ultimate number of citations. We validate our approach using the publication records of 1,283 researchers from seven scientific disciplines. Our approach has three distinct advantages. First, it accurately captures the overall scientific impact of researchers, as measured by ultimate citation counts. Second, in contrast to prior bibliometric indicators, our proposed measure does not depend on the number of publications, offering the possibility to compare researchers at different career stages. Third, more than other measures, our index is resistant to manipulation and rewards publication quality over quantity. The authors acknowledge the support of FCT-Portugal grant SFRH/BD/76115/2011 and NSF awards SBE 0624318 and IIS 0830388.

  18. Pitfalls in developmental diagnosis.

    PubMed Central

    Illingworth, R S

    1987-01-01

    I have never seen a paper or chapter of a book devoted to pitfalls and mistakes in developmental diagnosis. This paper is designed to try to fill the gap. It concerns the avoidance of mistakes in developmental diagnosis and is based entirely on mistakes that I have made myself and now learned to try to avoid and on mistakes that I have seen, most of them repeatedly. I have made no mention of mistakes that could theoretically be made but that I have not personally seen. I believe that most assessment errors are due to overconfidence and to the view that developmental diagnosis is easy. Many other mistakes are due to reliance on purely objective tests with consequent omission of a detailed history and physical examination, so that factors that profoundly affect development but are not directly related to the child's mental endowment are not weighed up before an opinion is reached. PMID:2444167

  19. Plagiarism in scientific research and publications and how to prevent it.

    PubMed

    Masic, Izet

    2014-04-01

    Quality is assessed on the basis of adequate evidence, while best results of the research are accomplished through scientific knowledge. Information contained in a scientific work must always be based on scientific evidence. Guidelines for genuine scientific research should be designed based on real results. Dynamic research and use correct methods of scientific work must originate from everyday practice and the fundamentals of the research. The original work should have the proper data sources with clearly defined research goals, methods of operation which are acceptable for questions included in the study. When selecting the methods it is necessary to obtain the consent of the patients/respondents to provide data for execution of the project or so called informed consent. Only by the own efforts can be reached true results, from which can be drawn conclusions and which finally can give a valid scholarly commentary. Text may be copied from other sources, either in whole or in part and marked as a result of the other studies. For high-quality scientific work necessary are expertise and relevant scientific literature, mostly taken from publications that are stored in biomedical databases. These are scientific, professional and review articles, case reports of disease in physician practices, but the knowledge can also be acquired on scientific and expert lectures by renowned scientists. Form of text publications must meet standards on writing a paper. If the article has already been published in a scientific journal, the same article cannot be published in any other journal with a few minor adjustments, or without specifying the parts of the first article which is used in another article. Copyright infringement occurs when the author of a new article, with or without mentioning the author, uses a substantial portion of previously published articles, including past contributions in the first article. With the permission of the publisher and the author, another journal

  20. Plagiarism in Scientific Research and Publications and How to Prevent It

    PubMed Central

    Masic, Izet

    2014-01-01

    Quality is assessed on the basis of adequate evidence, while best results of the research are accomplished through scientific knowledge. Information contained in a scientific work must always be based on scientific evidence. Guidelines for genuine scientific research should be designed based on real results. Dynamic research and use correct methods of scientific work must originate from everyday practice and the fundamentals of the research. The original work should have the proper data sources with clearly defined research goals, methods of operation which are acceptable for questions included in the study. When selecting the methods it is necessary to obtain the consent of the patients/respondents to provide data for execution of the project or so called informed consent. Only by the own efforts can be reached true results, from which can be drawn conclusions and which finally can give a valid scholarly commentary. Text may be copied from other sources, either in whole or in part and marked as a result of the other studies. For high-quality scientific work necessary are expertise and relevant scientific literature, mostly taken from publications that are stored in biomedical databases. These are scientific, professional and review articles, case reports of disease in physician practices, but the knowledge can also be acquired on scientific and expert lectures by renowned scientists. Form of text publications must meet standards on writing a paper. If the article has already been published in a scientific journal, the same article cannot be published in any other journal with a few minor adjustments, or without specifying the parts of the first article which is used in another article. Copyright infringement occurs when the author of a new article, with or without mentioning the author, uses a substantial portion of previously published articles, including past contributions in the first article. With the permission of the publisher and the author, another journal

  1. Improving Scientific Communication and Publication Output in a Multidisciplinary Laboratory: Changing Culture Through Staff Development Workshops

    SciTech Connect

    Noonan, Christine F.; Stratton, Kelly G.

    2015-07-13

    Communication plays a fundamental role in science and engineering disciplines. However, many higher education programs provide little, if any, technical communication coursework. Without strong communication skills scientists and engineers have less opportunity to publish, obtain competitive research funds, or grow their careers. This article describes the role of scientific communication training as an innovative staff development program in a learning-intensive workplace – a national scientific research and development laboratory. The findings show that involvement in the workshop has increased overall participating staff annual publications by an average of 61 percent compared to their pre-workshop publishing performance as well as confidence level in their ability to write and publish peer-reviewed literature. Secondary benefits include improved information literacy skills and the development of informal communities of practice. This work provides insight into adult education in the workplace.

  2. Identification of trends in scientific publications related to genetic polymorphisms in gestational diabetes mellitus.

    PubMed

    Gomes, J S; Minasi, L B; da Cruz, A D; Rodrigues, F M

    2016-01-01

    Gestational diabetes is a genetic multifactorial systemic disease that has been extensively studied. Consequently, there is a large volume of scientific literature pertaining to genes associated with gestational diabetes. The aim of this study was to characterize the main trends in scientific publications focusing on the associations between genetic polymorphisms and gestational diabetes mellitus (GDM). The related articles were extracted from Scopus using the key words "genetic polymorphism" and "gestational diabetes mellitus"; the collected data focused on various fields (medical, biochemical, etc.) and included papers published within December 2013. One hundred and eighty-three relevant articles published between 1987 and 2013 were identified; we observed a significantly increasing trend in the number of publications pertaining to GDM. A majority of the articles focused on the medical (59.9%), biochemical, and genetics and molecular biological (29.6%) aspects of the disease. The genes coding for transcription factor 7-like 2 and glucokinase (TCF7L2, 29% and GCK, 28%) were predominantly studied and reported. This study helped quantify the growth in research pertaining to GDM; researchers from the USA have published a majority of the publications related to GDM. Several candidate genes have been linked to diabetes; however, the specific gene locus responsible for GDM has not yet been identified. The results of this study could help determine the orientation of future research on genetic factors associated with GDM. PMID:27173344

  3. [History of the Halle Ars medica Judaica. V. Scientific achievements and medical publications of 2 centuries].

    PubMed

    Kaiser, W; Völker, A

    1989-05-01

    A medico-scientific journalism of Jewish origin which became increasedly recognizable on the German territory in the second half of the 17th century was at first based on the activities of Spanish-Portuguese exiles. Beginning with the 18th century at first the inaugural papers, but then also the publications of renowned Jewish physicians determined the profile of this literary group. The access to academic teaching professions becoming possible in the 19th century developed concentration points of research engagement, which in this place shall be indicated at the instance of the Medical Faculty of Halle University. PMID:2662660

  4. 75 FR 78338 - Notice of Public Meeting of the President's Emergency Plan for AIDS Relief (PEPFAR) Scientific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-15

    ... of Public Meeting of the President's Emergency Plan for AIDS Relief (PEPFAR) Scientific Advisory... Emergency Plan for AIDS Relief (PEPFAR) Scientific Advisory Board will meet on January 6-7, 2011 at the St.... Global AIDS Coordinator, Ambassador Eric Goosby, who leads implementation of the President's...

  5. 26 CFR 1.501(c)(3)-1 - Organizations organized and operated for religious, charitable, scientific, testing for public...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... purposes, see 26 CFR (1939) 39.101(6)-1 (Regulations 118) as made applicable to the Code by Treasury... 501(c)(3), includes the carrying on of scientific research in the public interest. Research when taken... particular research depends upon the purpose which it serves. For research to be scientific, within...

  6. 26 CFR 1.501(c)(3)-1 - Organizations organized and operated for religious, charitable, scientific, testing for public...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... purposes, see 26 CFR (1939) 39.101(6)-1 (Regulations 118) as made applicable to the Code by Treasury... 501(c)(3), includes the carrying on of scientific research in the public interest. Research when taken... particular research depends upon the purpose which it serves. For research to be scientific, within...

  7. Alcohol: a description and comparison of recent scientific vs. public knowledge.

    PubMed

    Buckalew, L W

    1979-04-01

    Sought to survey alcohol research since the "rediscovery" of fetal alcohol syndrome (FAS) and to compare recent scientific knowledge with that of the general public. Research was found to concentrate on searching for explanations of alcohol use and/or abuse and on several areas of biological morphogenesis. Significant documentation exists for FAS and validates both physiological and developmental attributes. As an index of public knowledge, an alcohol questionnaire was administered to 190 high-school, college, and graduate students. True-false items represented statements relative to the nature, etiology, effects, variables, and consequences of alcohol use/abuse. The composite mean of less than 60% correct suggested significant misinformation and misconceptions about alcohol. A summary of the most dramatic informational deficits was presented. There was a positive, though minimal, relationship between alcohol knowledge and education, and both sex and race differences were noted. PMID:457917

  8. SOUTH AMERICAN COLLABORATION IN SCIENTIFIC PUBLICATIONS ON LEISHMANIASIS: BIBLIOMETRIC ANALYSIS IN SCOPUS (2000-2011)

    PubMed Central

    Huamaní, Charles; Romaní, Franco; González-Alcaide, Gregorio; Mejia, Miluska O.; Ramos, José Manuel; Espinoza, Manuel; Cabezas, César

    2014-01-01

    Objectives: Evaluate the production and the research collaborative network on Leishmaniasis in South America. Methods: A bibliometric research was carried out using SCOPUS database. The analysis unit was original research articles published from 2000 to 2011, that dealt with leishmaniasis and that included at least one South American author. The following items were obtained for each article: journal name, language, year of publication, number of authors, institutions, countries, and others variables. Results: 3,174 articles were published, 2,272 of them were original articles. 1,160 different institutional signatures, 58 different countries and 398 scientific journals were identified. Brazil was the country with more articles (60.7%) and Oswaldo Cruz Foundation (FIOCRUZ) had 18% of Brazilian production, which is the South American nucleus of the major scientific network in Leishmaniasis. Conclusions: South American scientific production on Leishmaniasis published in journals indexed in SCOPUS is focused on Brazilian research activity. It is necessary to strengthen the collaboration networks. The first step is to identify the institutions with higher production, in order to perform collaborative research according to the priorities of each country. PMID:25229217

  9. The Disconnect Between Journalism and Science and its Role in Public Misunderstanding of Important Scientific Issues

    NASA Astrophysics Data System (ADS)

    Yulsman, T.

    2006-12-01

    Research shows that Americans' knowledge of science is sorely inaccurate. U.S. adults get most of their knowledge from the popular media, so it has been claimed that problems with media coverage of science are to blame. But this is a simplistic analysis. At their roots, scientific and journalistic modes of inquiry actually share two important normative standards: empiricism and skepticism. On the other hand, news and new scientific knowledge are two very different things. News gathering is guided in large measure by criteria that help journalists decide what is worth covering, as well as by standards of fairness and balance. The overarching goal is to report on things considered newsworthy in a neutral manner. In science, the goal is to ruthlessly discard incorrect ideas to get at the truth about nature. This talk will examine the "good" -- the normative standards that journalists and scientists share, as well as the "bad" -- how the significant disconnects between science and journalism may be contributing to a lack of public understanding of critical scientific issues such as climate change. Among the questions that will be addressed: How do journalists decide what is news? How does science fare when these newsworthiness standards are applied to it? How does the journalistic standard of balance result in inaccurate reporting on climate change? And how might we improve the situation by enhancing communication between scientists and journalist?

  10. The influence of cultural capital on consumption of scientific culture: A survey of visitors to an open house event at a public scientific research institution.

    PubMed

    Kato-Nitta, Naoko

    2013-04-01

    Based on the concept of cultural capital, this study explores the relationship between habitual behaviors of individuals regarding their past accumulation of such capital and current responses to a scientific institute's public outreach activity. At an open house held at the Institute for Molecular Science (IMS), anonymous questionnaires were distributed among 1,350 visitors and collected from 785 of them (collection rate = 58.1%). The results, measuring the past five to six years, showed that the respondents accumulated cultural capital through participation in scientific activities as well as in activities involving art, music, and literature. Given these quantified values, correlations between citizens' levels of accumulated cultural capital and their current scientific consumption behavior were studied. A statistical analysis of the two components of cultural capital (science and technology/art and literature) showed that people's accumulated scientific capital influenced their current behavior and revealed a correlation between the two components. PMID:23833057

  11. Scientific composition and review of manuscripts for publication in peer-reviewed dental journals.

    PubMed

    Bayne, Stephen C; McGivney, Glen P; Mazer, Sarah C

    2003-02-01

    This article provides an extensive tutorial for writers and reviewers involved with the preparation and evaluation of manuscripts submitted for publication in dental journals. The contents were compiled from the Instructions for Authors printed in various peer-reviewed dental journals and from feedback from 10 workshops conducted for the Editorial Review Board of the Journal of Prosthetic Dentistry. The 10 major sections of a scientific manuscript are reviewed in detail in terms of content, format, and common errors; examples of good content are provided. The review process is described, and instructions on conducting fair and expeditious manuscript evaluations are provided for reviewers. In addition, a number of special topics are addressed, including potential conflicts of interest for an author, institutional review of experiments that involve human subjects or animals, and the reproduction of photographs and other images in color versus black and white. In summary, this article presents key guidelines to ensure compliance with the principles of sound scientific writing and the expeditious review of manuscripts prepared for publication in peer-reviewed dental journals. PMID:12616242

  12. The Scientific Publications of Richard H. Dalitz, FRS (1925-2006)

    SciTech Connect

    Aitchison, Ian J.R.; Close, Frank E.; Gal, Avraham; Millener, D.John

    2006-03-29

    Professor Richard H. Dalitz passed away on January 13, 2006. He was almost 81 years old and his outstanding contributions are intimately connected to some of the major breakthroughs of the 20th century in particle and nuclear physics. These outstanding contributions go beyond the Dalitz Plot, Dalitz Pair and CDD poles that bear his name. He pioneered the theoretical study of strange baryon resonances, of baryon spectroscopy in the quark model, and of hypernuclei, to all of which he made lasting contributions. His formulation of the ''{theta} - {tau} puzzle'' led to the discovery that parity is not a symmetry of the weak interactions. A brief scientific evaluation of Dalitz's major contributions to particle and nuclear physics is hereby presented, followed by the first comprehensive list of his scientific publications, as assembled from several sources. The list is divided into two categories: the first, main part comprises Dalitz's research papers and reviews, including topics in the history of particle physics, biographies and reminescences; the second part lists book reviews, public lectures and obituaries authored by Dalitz, and books edited by him. This provides the first necessary step towards a more systematic research of the Dalitz heritage in modern physics.

  13. Masculine Knowledge, the Public Good, and the Scientific Household of Réaumur.

    PubMed

    Terrall, Mary

    2015-01-01

    In the Royal Academy of Sciences of Paris (founded 1666), expressions of a masculine culture of science echoed contemporary language used to articulate the aristocracy's value to crown and state--even though the academy was not an aristocratic institution as such. In the eighteenth century, the pursuit of science became a new form of manly service to the crown, often described in terms of useful knowledge and benefit to the public good [le bien public]. This article explores the connection of academic scientific knowledge to the domestic spaces where it was made and, in particular, to the household of R.-A. Ferchault de Réaumur, an exemplary academician. Although Réaumur had neither wife nor children, a complex net of affective ties, some of them familial, linked the members of the household, which accommodated women (the artist Hélène Dumoustier and her female relatives) as well as men (a series of assistants, many of whom eventually entered the academy). As head of this dynamic household, Réaumur produced not only scientific results but also future academicians. PMID:27066624

  14. Clustering Scientific Publications Based on Citation Relations: A Systematic Comparison of Different Methods

    PubMed Central

    Šubelj, Lovro; van Eck, Nees Jan; Waltman, Ludo

    2016-01-01

    Clustering methods are applied regularly in the bibliometric literature to identify research areas or scientific fields. These methods are for instance used to group publications into clusters based on their relations in a citation network. In the network science literature, many clustering methods, often referred to as graph partitioning or community detection techniques, have been developed. Focusing on the problem of clustering the publications in a citation network, we present a systematic comparison of the performance of a large number of these clustering methods. Using a number of different citation networks, some of them relatively small and others very large, we extensively study the statistical properties of the results provided by different methods. In addition, we also carry out an expert-based assessment of the results produced by different methods. The expert-based assessment focuses on publications in the field of scientometrics. Our findings seem to indicate that there is a trade-off between different properties that may be considered desirable for a good clustering of publications. Overall, map equation methods appear to perform best in our analysis, suggesting that these methods deserve more attention from the bibliometric community. PMID:27124610

  15. Clustering Scientific Publications Based on Citation Relations: A Systematic Comparison of Different Methods.

    PubMed

    Šubelj, Lovro; van Eck, Nees Jan; Waltman, Ludo

    2016-01-01

    Clustering methods are applied regularly in the bibliometric literature to identify research areas or scientific fields. These methods are for instance used to group publications into clusters based on their relations in a citation network. In the network science literature, many clustering methods, often referred to as graph partitioning or community detection techniques, have been developed. Focusing on the problem of clustering the publications in a citation network, we present a systematic comparison of the performance of a large number of these clustering methods. Using a number of different citation networks, some of them relatively small and others very large, we extensively study the statistical properties of the results provided by different methods. In addition, we also carry out an expert-based assessment of the results produced by different methods. The expert-based assessment focuses on publications in the field of scientometrics. Our findings seem to indicate that there is a trade-off between different properties that may be considered desirable for a good clustering of publications. Overall, map equation methods appear to perform best in our analysis, suggesting that these methods deserve more attention from the bibliometric community. PMID:27124610

  16. 76 FR 52731 - Notice of Public Meeting of the President's Emergency Plan for AIDS Relief (PEPFAR) Scientific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-23

    ... of Public Meeting of the President's Emergency Plan for AIDS Relief (PEPFAR) Scientific Advisory... open to the public. The meeting will be hosted by the Office of the U.S. Global AIDS Coordinator, Ambassador Eric Goosby, who leads implementation of the President's Emergency Plan for AIDS Relief...

  17. 77 FR 55891 - Notice of Public Meeting of the President's Emergency Plan for AIDS Relief (PEPFAR) Scientific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... of Public Meeting of the President's Emergency Plan for AIDS Relief (PEPFAR) Scientific Advisory... public. The meeting will be hosted by the Office of the U.S. Global AIDS Coordinator, and led by Ambassador Eric Goosby, who leads implementation of the President's Emergency Plan for AIDS Relief...

  18. 78 FR 55326 - Notice of Public Meeting of the President's Emergency Plan for AIDS Relief (PEPFAR) Scientific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-10

    ... of Public Meeting of the President's Emergency Plan for AIDS Relief (PEPFAR) Scientific Advisory... is open to the public. The meeting will be hosted by the Office of the U.S. Global AIDS Coordinator, and led by Ambassador Eric Goosby, who leads implementation of the President's Emergency Plan for...

  19. 76 FR 76725 - Notification of a Public Meeting of the Clean Air Scientific Advisory Committee (CASAC); Ozone...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-08

    ... AGENCY Notification of a Public Meeting of the Clean Air Scientific Advisory Committee (CASAC); Ozone... Advisory Board (SAB) Staff Office announces a public meeting of the CASAC Ozone Review Panel to conduct a peer review of EPA's Integrated Science Assessment for Ozone and Related Photochemical Oxidants...

  20. 77 FR 6796 - Notification of a Public Meeting of the Clean Air Scientific Advisory Committee (CASAC); Ozone...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-09

    .... The CASAC Ozone Review Panel held a face-to- face meeting on January 9-10, 2012 (as noticed in 76 FR... AGENCY Notification of a Public Meeting of the Clean Air Scientific Advisory Committee (CASAC); Ozone... Advisory Board (SAB) Staff Office announces a public teleconference of the CASAC Ozone Review Panel...

  1. Pitfalls in penetrating trauma.

    PubMed

    van Vugt, A B

    2003-08-01

    In Western Europe the most frequent cause of multiple injuries is blunt trauma. Only few of us have experience with penetrating trauma, without exception far less than in the USA or South-Africa. In Rotterdam, the Erasmus Medical Centre is a level I trauma centre, situated directly in the town centre. All penetrating traumas are directly presented to our emergency department by a well organized ambulance service supported by a mobile medical team if necessary. The delay with scoop and run principles is very short for these cases, resulting in severely injured reaching the hospital alive in increasing frequency. Although the basic principles of trauma care according to the guidelines of the Advanced Trauma Life Support (ATLS) (1-2) are the same for blunt and penetrating trauma with regard to priorities, diagnostics and primary therapy, there are some pitfalls in the strategy of management in penetrating trauma one should be aware of. Simple algorithms can be helpful, especially in case of limited experience (3). In case of life-saving procedures, the principles of Damage Control Surgery (DCS) must be followed (4-5). This approach is somewhat different from "traditional" surgical treatment. In the Ist phase prompt interventions by emergency thoracotomy and laparotomy are carried out, with only two goals to achieve: surgical control of haemorrhage and contamination. After temporary life-saving procedures, the 2nd phase is characterized by intensive care treatment, dealing with hypothermia, metabolic acidosis and clotting disturbances. Finally in the 3rd phase, within 6-24 hours, definitive surgical care takes place. In this overview, penetrating injuries of neck, thorax, abdomen and extremities will be outlined. Penetrating cranial injuries, as a neurosurgical emergency with poor prognosis, are not discussed. History and physical examination remain the corner stones of good medical praxis. In a work-up according to ATLS principles airway, breathing and circulation

  2. Disasters related to droughts and public health - a review of the scientific literature.

    PubMed

    Alpino, Tais Ariza; de Sena, Aderita Ricarda Martins; de Freitas, Carlos Machado

    2016-03-01

    In Brazil, the history of droughts has been marked by constant social and health tragedies, with estimates of up to 3 million deaths from the early 19th century until the late 20th century. There is a record of nearly 32,000 events related to the above and more than 96 million people were affected between 1991 and 2010. Although droughts have historically brought disasters to Brazil, which was noted in the scientific expeditions of Arthur Neiva and Belisario Penna that documented these droughts, there have not been many studies on them. The objective of this paper is to present a revision of the scientific articles related to droughts and public health. The following databases were used: PubMed, the Preparation and Response to Disasters Portal from BVS and the Capes Periodical Portal. The descriptors drought and health were used to search titles and summaries of articles in English, Portuguese and Spanish. Among the repercussions related to health that were discovered: malnutrition and nutritional deficiencies, mental health problems, issues relating to water and air quality and commitments made concerning access to health services. As there is a trend for more intense droughts and a scarcity of water until 2030, there is an urgent need for more research and studies in these areas. PMID:26960093

  3. Art, Aesthetics, Design, And Data: Reaching The Public Through Scientific Visualization

    NASA Astrophysics Data System (ADS)

    Simmon, R.; Allen, J.; Ward, K.; Carlowicz, M. J.

    2012-12-01

    The primary challenge in science communication is attracting a broad audience while maintaining technical accuracy. Scientific topics are often and reflexively considered boring, dry, or difficult by non-scientists. One way to overcome this hurdle and gain the public's attention is through beautiful and striking imagery. Imaging techniques borrowed from art and design can generate interest in technical or abstract concepts. NASA's Earth Observatory routinely uses imagery to communicate current Earth science research. Earth Observatory designers collaborate with NASA scientists to produce imagery using the principles of data visualization. Curiously, the popularity of images tends to be inversely correlated with the scientific content. Simple photographs and illustrations tend to be viewed more often, and more widely shared, than maps and graphs. However, maps of tree density and melt on the Greenland ice sheet are among the most popular images published on the Earth Observatory. These graphics share some features both with each other and our most-viewed natural-color images: clear, relatable themes, intuitive color palettes, and a clean aesthetic. These similarities may explain their success, and provide a roadmap for future data-rich visualizations that engage viewers while communicating complex science.This map of tree density in the united states, based on the National Biomass and Carbon Dataset (NBCD) is one of the NASA Earth Observatory's most popular data-based images. (Map by Robert Simmon, based on data from Woods Hole Research Center.)

  4. The Einstein Observatory: A New Public/Private Observatory Complex for Community Education and Scientific Research

    NASA Astrophysics Data System (ADS)

    Sowell, J.

    1999-12-01

    The Development Authority of Cherokee County (Georgia) is leading a public/private partnership of business/industry professionals, educators, and university scientists that seeks to develop a national prototype educational and scientific research facility for grades K-12, as well as college-level research, that will inspire our youth to become literate in science and technology. In particular, the goal is to make this complex a science, math, and engineering magnet learning facility and to raise the average SAT scores of local area students by 100 points. A dark-site mountain, nestled on the foothills of the Blue Ridge Mountains at the northern-most edge of Atlanta, will become the home for the "Einstein" Observatory. The complex will have four telescopes: one 50-inch, one 24-inch, and two 16-inch telescopes. Each telescope will have digital cameras and an optic-fiber feed to a single, medium-resolution spectroscope. All four telescopes will be electronically accessible from local schools. Professional astronomers will establish suitable observational research projects and will lead K-12 and college students in the acquisition and analysis of data. Astronomers will also assist the local area schoolteachers in methods for nurturing children's scientific inquiry. The observatory mountain will have 100 platform locations for individual viewing by visiting families, school groups, and amateur astronomers. The Atlanta Astronomer Club will provide numerous evening programs and viewing opportunities for the general public. An accompanying Planetarium & Science Center will be located on the nearby campus of Reinhardt College. The Planetarium & Science Center will be integrated with Reinhardt College's theme of learning focused upon studying the past and present as a basis for projecting the future.

  5. 42 CFR 82.30 - How will NIOSH inform the public of any plans to change scientific elements underlying the dose...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... change scientific elements underlying the dose reconstruction process to maintain methods reasonably current with scientific progress? 82.30 Section 82.30 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF... 2000 Updating the Scientific Elements Underlying Dose Reconstructions § 82.30 How will NIOSH inform...

  6. 42 CFR 82.30 - How will NIOSH inform the public of any plans to change scientific elements underlying the dose...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... change scientific elements underlying the dose reconstruction process to maintain methods reasonably current with scientific progress? 82.30 Section 82.30 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF... 2000 Updating the Scientific Elements Underlying Dose Reconstructions § 82.30 How will NIOSH inform...

  7. 42 CFR 82.30 - How will NIOSH inform the public of any plans to change scientific elements underlying the dose...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... change scientific elements underlying the dose reconstruction process to maintain methods reasonably current with scientific progress? 82.30 Section 82.30 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF... 2000 Updating the Scientific Elements Underlying Dose Reconstructions § 82.30 How will NIOSH inform...

  8. 42 CFR 82.30 - How will NIOSH inform the public of any plans to change scientific elements underlying the dose...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... change scientific elements underlying the dose reconstruction process to maintain methods reasonably current with scientific progress? 82.30 Section 82.30 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF... 2000 Updating the Scientific Elements Underlying Dose Reconstructions § 82.30 How will NIOSH inform...

  9. 42 CFR 82.30 - How will NIOSH inform the public of any plans to change scientific elements underlying the dose...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... change scientific elements underlying the dose reconstruction process to maintain methods reasonably current with scientific progress? 82.30 Section 82.30 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF... 2000 Updating the Scientific Elements Underlying Dose Reconstructions § 82.30 How will NIOSH inform...

  10. [Evaluation of scientific production in different subareas of Public Health: limits of the current model and contributions to the debate].

    PubMed

    Iriart, Jorge Alberto Bernstein; Deslandes, Suely Ferreira; Martin, Denise; Camargo Jr, Kenneth Rochel de; Carvalho, Marilia Sá; Coeli, Cláudia Medina

    2015-10-01

    The aim of this study was to discuss the limits of the quantitative evaluation model for scientific production in Public Health. An analysis of the scientific production of professors from the various subareas of Public Health was performed for 2010-2012. Distributions of the mean annual score for professors were compared according to subareas. The study estimated the likelihood that 60% of the professors in the graduate studies programs scored P50 (Very Good) or higher in their area. Professors of Epidemiology showed a significantly higher median annual score. Graduate studies programs whose faculty included at least 60% of Epidemiology professors and fewer than 10% from the subarea Social and Human Sciences in Health were significantly more likely to achieve a "Very Good" classification. The observed inequalities in scientific production between different subareas of Public Health point to the need to rethink their evaluation in order to avoid reproducing iniquities that have harmful consequences for the field's diversity. PMID:26735381

  11. Enhancing Scientific Collaboration, Transparency, and Public Access: Utilizing the Second Life Platform to Convene a Scientific Conference in 3-D Virtual Space

    NASA Astrophysics Data System (ADS)

    McGee, B. W.

    2006-12-01

    Recent studies reveal a general mistrust of science as well as a distorted perception of the scientific method by the public at-large. Concurrently, the number of science undergraduate and graduate students is in decline. By taking advantage of emergent technologies not only for direct public outreach but also to enhance public accessibility to the science process, it may be possible to both begin a reversal of popular scientific misconceptions and to engage a new generation of scientists. The Second Life platform is a 3-D virtual world produced and operated by Linden Research, Inc., a privately owned company instituted to develop new forms of immersive entertainment. Free and downloadable to the public, Second Life offers an imbedded physics engine, streaming audio and video capability, and unlike other "multiplayer" software, the objects and inhabitants of Second Life are entirely designed and created by its users, providing an open-ended experience without the structure of a traditional video game. Already, educational institutions, virtual museums, and real-world businesses are utilizing Second Life for teleconferencing, pre-visualization, and distance education, as well as to conduct traditional business. However, the untapped potential of Second Life lies in its versatility, where the limitations of traditional scientific meeting venues do not exist, and attendees need not be restricted by prohibitive travel costs. It will be shown that the Second Life system enables scientific authors and presenters at a "virtual conference" to display figures and images at full resolution, employ audio-visual content typically not available to conference organizers, and to perform demonstrations or premier three-dimensional renderings of objects, processes, or information. An enhanced presentation like those possible with Second Life would be more engaging to non- scientists, and such an event would be accessible to the general users of Second Life, who could have an

  12. The rate of growth in scientific publication and the decline in coverage provided by Science Citation Index

    PubMed Central

    von Ins, Markus

    2010-01-01

    The growth rate of scientific publication has been studied from 1907 to 2007 using available data from a number of literature databases, including Science Citation Index (SCI) and Social Sciences Citation Index (SSCI). Traditional scientific publishing, that is publication in peer-reviewed journals, is still increasing although there are big differences between fields. There are no indications that the growth rate has decreased in the last 50 years. At the same time publication using new channels, for example conference proceedings, open archives and home pages, is growing fast. The growth rate for SCI up to 2007 is smaller than for comparable databases. This means that SCI was covering a decreasing part of the traditional scientific literature. There are also clear indications that the coverage by SCI is especially low in some of the scientific areas with the highest growth rate, including computer science and engineering sciences. The role of conference proceedings, open access archives and publications published on the net is increasing, especially in scientific fields with high growth rates, but this has only partially been reflected in the databases. The new publication channels challenge the use of the big databases in measurements of scientific productivity or output and of the growth rate of science. Because of the declining coverage and this challenge it is problematic that SCI has been used and is used as the dominant source for science indicators based on publication and citation numbers. The limited data available for social sciences show that the growth rate in SSCI was remarkably low and indicate that the coverage by SSCI was declining over time. National Science Indicators from Thomson Reuters is based solely on SCI, SSCI and Arts and Humanities Citation Index (AHCI). Therefore the declining coverage of the citation databases problematizes the use of this source. PMID:20700371

  13. Connecting the Public to Scientific Research Data - Science On a Sphere°

    NASA Astrophysics Data System (ADS)

    Henderson, M. A.; Russell, E. L.; Science on a Sphere Datasets

    2011-12-01

    Connecting the Public to Scientific Research Data - Science On a Sphere° Maurice Henderson, NASA Goddard Space Flight Center Elizabeth Russell, NOAA Earth System Research Laboratory, University of Colorado Cooperative Institute for Research in Environmental Sciences Science On a Sphere° is a six foot animated globe developed by the National Ocean and Atmospheric Administration, NOAA, as a means to display global scientific research data in an intuitive, engaging format in public forums. With over 70 permanent installations of SOS around the world in science museums, visitor's centers and universities, the audience that enjoys SOS yearly is substantial, wide-ranging, and diverse. Through partnerships with the National Aeronautics and Space Administration, NASA, the SOS Data Catalog (http://sos.noaa.gov/datasets/) has grown to a collection of over 350 datasets from NOAA, NASA, and many others. Using an external projection system, these datasets are displayed onto the sphere creating a seamless global image. In a cross-site evaluation of Science On a Sphere°, 82% of participants said yes, seeing information displayed on a sphere changed their understanding of the information. This unique technology captivates viewers and exposes them to scientific research data in a way that is accessible, presentable, and understandable. The datasets that comprise the SOS Data Catalog are scientific research data that have been formatted for display on SOS. By formatting research data into visualizations that can be used on SOS, NOAA and NASA are able to turn research data into educational materials that are easily accessible for users. In many cases, visualizations do not need to be modified because SOS uses a common map projection. The SOS Data Catalog has become a "one-stop shop" for a broad range of global datasets from across NOAA and NASA, and as a result, the traffic on the site is more than just SOS users. While the target audience for this site is SOS users, many

  14. Tackling the "so what" problem in scientific research: a systems-based approach to resource and publication tracking.

    PubMed

    Harris, Paul A; Kirby, Jacqueline; Swafford, Jonathan A; Edwards, Terri L; Zhang, Minhua; Yarbrough, Tonya R; Lane, Lynda D; Helmer, Tara; Bernard, Gordon R; Pulley, Jill M

    2015-08-01

    Peer-reviewed publications are one measure of scientific productivity. From a project, program, or institutional perspective, publication tracking provides the quantitative data necessary to guide the prudent stewardship of federal, foundation, and institutional investments by identifying the scientific return for the types of support provided. In this article, the authors describe the Vanderbilt Institute for Clinical and Translational Research's (VICTR's) development and implementation of a semiautomated process through which publications are automatically detected in PubMed and adjudicated using a "just-in-time" workflow by a known pool of researchers (from Vanderbilt University School of Medicine and Meharry Medical College) who receive support from Vanderbilt's Clinical and Translational Science Award. Since implementation, the authors have (1) seen a marked increase in the number of publications citing VICTR support, (2) captured at a more granular level the relationship between specific resources/services and scientific output, (3) increased awareness of VICTR's scientific portfolio, and (4) increased efficiency in complying with annual National Institutes of Health progress reports. They present the methodological framework and workflow, measures of impact for the first 30 months, and a set of practical lessons learned to inform others considering a systems-based approach for resource and publication tracking. They learned that contacting multiple authors from a single publication can increase the accuracy of the resource attribution process in the case of multidisciplinary scientific projects. They also found that combining positive (e.g., congratulatory e-mails) and negative (e.g., not allowing future resource requests until adjudication is complete) triggers can increase compliance with publication attribution requests. PMID:25901872

  15. Personnel Pitfalls in Cyberworld

    ERIC Educational Resources Information Center

    Wheeler, Thomas E., III

    2007-01-01

    In May 2006 administrators in the Austin, Texas, Independent School District learned that Tamara Hoover, an art teacher at Austin High School, was the subject of several explicit photographs that had been posted on Flickr, a public photograph-sharing website. Purportedly these photographs were posted on Flickr by the teacher's partner without her…

  16. 75 FR 22783 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-30

    ...There will be a 1-day meeting of the Federal Insecticide, Fungicide, and Rodenticide Act. Scientific Advisory Panel (FIFRA SAP) to consider and review a set of scientific issues related to the Comparative Adult and Juvenile Sensitivity Toxicity Protocols for...

  17. Chaos: A New Scientific Paradigm--Or Science by Public Relations?

    ERIC Educational Resources Information Center

    Dresden, Max

    1992-01-01

    Discusses the emergence of chaos as a major scientific subject and its place in historical, scientific, and technological context. Three sections provide (1) an overview of the scientific paradigm; (2) a review of the ideology of classical mechanics; and (3) examples of classical systems behaving in peculiar, nonintuitive manners. (MDH)

  18. Are Lipases Still Important Biocatalysts? A Study of Scientific Publications and Patents for Technological Forecasting

    PubMed Central

    Daiha, Karina de Godoy; Angeli, Renata; de Oliveira, Sabrina Dias; Almeida, Rodrigo Volcan

    2015-01-01

    The great potential of lipases is known since 1930 when the work of J. B. S. Haldane was published. After eighty-five years of studies and developments, are lipases still important biocatalysts? For answering this question the present work investigated the technological development of four important industrial sectors where lipases are applied: production of detergent formulations; organic synthesis, focusing on kinetic resolution, production of biodiesel, and production of food and feed products. The analysis was made based on research publications and patent applications, working as scientific and technological indicators, respectively. Their evolution, interaction, the major players of each sector and the main subject matters disclosed in patent documents were discussed. Applying the concept of technology life cycle, S-curves were built by plotting cumulative patent data over time to monitor the attractiveness of each technology for investment. The results lead to a conclusion that the use of lipases as biocatalysts is still a relevant topic for the industrial sector, but developments are still needed for lipase biocatalysis to reach its full potential, which are expected to be achieved within the third, and present, wave of biocatalysis. PMID:26111144

  19. Are Lipases Still Important Biocatalysts? A Study of Scientific Publications and Patents for Technological Forecasting.

    PubMed

    Daiha, Karina de Godoy; Angeli, Renata; de Oliveira, Sabrina Dias; Almeida, Rodrigo Volcan

    2015-01-01

    The great potential of lipases is known since 1930 when the work of J. B. S. Haldane was published. After eighty-five years of studies and developments, are lipases still important biocatalysts? For answering this question the present work investigated the technological development of four important industrial sectors where lipases are applied: production of detergent formulations; organic synthesis, focusing on kinetic resolution, production of biodiesel, and production of food and feed products. The analysis was made based on research publications and patent applications, working as scientific and technological indicators, respectively. Their evolution, interaction, the major players of each sector and the main subject matters disclosed in patent documents were discussed. Applying the concept of technology life cycle, S-curves were built by plotting cumulative patent data over time to monitor the attractiveness of each technology for investment. The results lead to a conclusion that the use of lipases as biocatalysts is still a relevant topic for the industrial sector, but developments are still needed for lipase biocatalysis to reach its full potential, which are expected to be achieved within the third, and present, wave of biocatalysis. PMID:26111144

  20. 78 FR 31626 - Notice of Public Meeting of the President's Emergency Plan for AIDS Relief (PEPFAR) Scientific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ... of Public Meeting of the President's Emergency Plan for AIDS Relief (PEPFAR) Scientific Advisory... will be hosted by the Office of the U.S. Global AIDS Coordinator, and led by Dr. Amy DuBois, who is the.... The Board serves the Global AIDS Coordinator in a solely advisory capacity concerning...

  1. 78 FR 33144 - Notice of Public Meeting of the President's Emergency Plan for AIDS Relief (PEPFAR) Scientific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-03

    ... of Public Meeting of the President's Emergency Plan for AIDS Relief (PEPFAR) Scientific Advisory... will be hosted by the Office of the U.S. Global AIDS Coordinator, and led by Dr. Amy DuBois, who is the.... The Board serves the Global AIDS Coordinator in a solely advisory capacity concerning...

  2. Group Projects as a Method of Promoting Student Scientific Communication and Collaboration in a Public Health Microbiology Course

    ERIC Educational Resources Information Center

    Walton, Kristen L. W.; Baker, Jason C.

    2009-01-01

    Communication of scientific and medical information and collaborative work are important skills for students pursuing careers in health professions and other biomedical sciences. In addition, group work and active learning can increase student engagement and analytical skills. Students in our public health microbiology class were required to work…

  3. 75 FR 54146 - Science Advisory Board Staff Office; Notification of a Public Meeting of the Clean Air Scientific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-03

    ...The Environmental Protection Agency (EPA or Agency) Science Advisory Board (SAB) Staff Office announces a public meeting on September 29-30, 2010, of the Clean Air Scientific Advisory Committee (CASAC) Ambient Air Monitoring & Methods Subcommittee (AAMMS) to provide advice concerning the development of a guidance document on network design for near-road ambient air monitoring and the......

  4. Utilizing Public Scientific Web Lectures to Teach Contemporary Physics at the High School Level: A Case Study of Learning

    ERIC Educational Resources Information Center

    Kapon, Shulamit; Ganiel, Uri; Eylon, Bat Sheva

    2011-01-01

    This paper describes a teaching experiment designed to examine the learning (i.e., retention of content and conceptual development) that takes place when public scientific web lectures delivered by scientists are utilized to present advanced ideas in physics to students with a high school background in physics. The students watched an exemplary…

  5. The Big Bang-steady state controversy: Cosmology in public and scientific forums

    NASA Astrophysics Data System (ADS)

    McConnell, Craig Sean

    A highly visible debate emerged in the 1950s and 1960s over two rival cosmologies, the big bang and the steady state. Cosmologists operated in three distinct forums of discourse---a specialists' forum in cosmology, a general science forum, and a diverse popular science forum. Each forum had its own implicit standards and conventions of argument which collectively shaped the development of cosmology. I argue that the popular forum framed the debate in the early 1950s, when the paucity of cosmologically significant evidence discouraged the involvement of most members of the physical-science community, who felt that cosmological theories lacked testability, the hallmark of respectable science. The conventions of the popular forum, in contrast welcomed cosmological arguments and subsequently shaped the expectations for the eventual resolution of the debate in all three forums. The debate was resolved in favor of the big bang in the 1960s and 1970s on the basis of a number of novel cosmologically relevant observations. Many publications in the popular science forum, however, marked the discovery of the cosmic background radiation in 1965 as the watershed moment that settled the dispute, casting the observation in the narrative framework of a crucial experiment. In the specialists' and general science forums final resolution came later, more gradually, and on the basis of a variety of evidence; yet many historians and cosmologists subsequently adopted the myth of the crucial experiment. This dissertation documents the influence of popular discussion in the 1950s on narratives of resolution in the 1970s and beyond, and recaptures the gradual process of resolution, a process that proceeded at different rates in different quarters. Unlike controversies in the history of science that have been resolved by a small "core-set" of specialists, the big bang-steady state debate was resolved in the general science forum by hundreds of interested participants who had come to see

  6. Modeling the Uptake of Scientific Information by the Public and Opinion Flow in Society (Invited)

    NASA Astrophysics Data System (ADS)

    Lewandowsky, S.; Brown, G. D.; Cook, J.

    2013-12-01

    Improved communication of scientific findings requires knowledge not only of how people process information, but also how such information spreads through society and how people's opinions are shaped by those of others. Recent advances in cognitive science have yielded mathematical modeling techniques that permit the detailed analysis of individuals' cognition as well as the behavior of communities in the aggregate. We present two case studies that highlight the insights that can be derived from mathematical models of cognition: We show how rational processing of information (i.e., Bayesian hypothesis revision) can nonetheless give rise to seemingly 'irrational' belief updating, as for example when acceptance of human-caused global warming decreases among conservatives in response to evidence for human-caused global warming. We also show in an agent-based simulation how social norms can lead to polarization of societies. The model assumes that agents located within a social network observe the behavior of neighbours and infer from their behavior the social distribution of particular attitudes (e.g. towards climate change). Agents are assumed to dislike behaviours that are extreme within their neighbourhood (social extremeness aversion), and hence have a tendency to conform. However, agents are also assumed to prefer choices that are consistent with their own true beliefs (authenticity preference). Expression of attitudes reflects a compromise between these opposing principles. The model sheds light on the role of perceived rather than actual social consensus on attitudes to climate change. This is particularly relevant given the widespread perception among those who reject climate science that the percentage of the public that is sharing their beliefs is much higher than it actually is.

  7. Cannabidiol: Promise and Pitfalls

    PubMed Central

    Welty, Timothy E.; Luebke, Adrienne; Gidal, Barry E.

    2014-01-01

    Over the past few years, increasing public and political pressure has supported legalization of medical marijuana. One of the main thrusts in this effort has related to the treatment of refractory epilepsy—especially in children with Dravet syndrome—using cannabidiol (CBD). Despite initiatives in numerous states to at least legalize possession of CBD oil for treating epilepsy, little published evidence is available to prove or disprove the efficacy and safety of CBD in patients with epilepsy. This review highlights some of the basic science theory behind the use of CBD, summarizes published data on clinical use of CBD for epilepsy, and highlights issues related to the use of currently available CBD products. Cannabidiol is the major nonpsychoactive component of Cannabis sativa. Over the centuries, a number of medicinal preparations derived from C. sativa have been employed for a variety of disorders, including gout, rheumatism, malaria, pain, and fever. These preparations were widely employed as analgesics by Western medical practitioners in the 19th century (1). More recently, there is clinical evidence suggesting efficacy in HIV-associated neuropathic pain, as well as spasms associated with multiple sclerosis (1). PMID:25346628

  8. Cannabidiol: promise and pitfalls.

    PubMed

    Welty, Timothy E; Luebke, Adrienne; Gidal, Barry E

    2014-09-01

    Over the past few years, increasing public and political pressure has supported legalization of medical marijuana. One of the main thrusts in this effort has related to the treatment of refractory epilepsy-especially in children with Dravet syndrome-using cannabidiol (CBD). Despite initiatives in numerous states to at least legalize possession of CBD oil for treating epilepsy, little published evidence is available to prove or disprove the efficacy and safety of CBD in patients with epilepsy. This review highlights some of the basic science theory behind the use of CBD, summarizes published data on clinical use of CBD for epilepsy, and highlights issues related to the use of currently available CBD products. Cannabidiol is the major nonpsychoactive component of Cannabis sativa. Over the centuries, a number of medicinal preparations derived from C. sativa have been employed for a variety of disorders, including gout, rheumatism, malaria, pain, and fever. These preparations were widely employed as analgesics by Western medical practitioners in the 19(th) century (1). More recently, there is clinical evidence suggesting efficacy in HIV-associated neuropathic pain, as well as spasms associated with multiple sclerosis (1). PMID:25346628

  9. Stanford-Based HighWire Press Transforms the Publication of Scientific Journals.

    ERIC Educational Resources Information Center

    Young, Jeffrey R.

    1997-01-01

    In two years, HighWire Press at Stanford University (California) has revolutionized online scientific publishing; electronic journals are reaching readers faster, are easier to search, and are entering new foreign markets. The largest scientific publishers will put about 200 journals online in 1997. Other changes foreseen include immediate rather…

  10. The Scientific Creationist Challenge to the Treatment of Evolution in the Public School Curriculum.

    ERIC Educational Resources Information Center

    Kube-McDowell, Michael P.

    The purpose of the study was to identify and analyze the scientific elements of the creationist position, and to provide information and recommendations to educators facing the question of adding creationism to the science curriculum. The claim that creationism is of equal scientific status with evolution is examined in the first part of the…

  11. 77 FR 68773 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-16

    ...There will be a 4-day meeting of the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review scientific issues associated with Prioritizing the Universe of Endocrine Disruptor Screening Program (EDSP) Chemicals Using Computational Toxicology...

  12. 75 FR 33300 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-11

    ...There will be a 4-day meeting of the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review a set of scientific issues related to the Re- Evaluation of Human Health Effects of Atrazine: Review of Non-Cancer Effects and Drinking Water Monitoring...

  13. 75 FR 22779 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-30

    ...There will be a 3-day meeting of the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review a set of scientific issues related to review of SHEDs-Multimedia version 4, Peer consult on PBPK Modeling, and a SHEDS- PBPK Permethrin...

  14. Communicating Scientific Findings to Lawyers, Policy-Makers, and the Public (Invited)

    NASA Astrophysics Data System (ADS)

    Thompson, W.; Velsko, S. P.

    2013-12-01

    This presentation will summarize the authors' collaborative research on inferential errors, bias and communication difficulties that have arisen in the area of WMD forensics. This research involves analysis of problems that have arisen in past national security investigations, interviews with scientists from various disciplines whose work has been used in WMD investigations, interviews with policy-makers, and psychological studies of lay understanding of forensic evidence. Implications of this research for scientists involved in nuclear explosion monitoring will be discussed. Among the issues covered will be: - Potential incompatibilities between the questions policy makers pose and the answers that experts can provide. - Common misunderstandings of scientific and statistical data. - Advantages and disadvantages of various methods for describing and characterizing the strength of scientific findings. - Problems that can arise from excessive hedging or, alternatively, insufficient qualification of scientific conclusions. - Problems that can arise from melding scientific and non-scientific evidence in forensic assessments.

  15. Apollo telescope mount. A partial listing of scientific publications and presentations, supplement 1

    NASA Technical Reports Server (NTRS)

    Reynolds, J. M. (Editor); Snoddy, W. C. (Editor)

    1977-01-01

    Compilations of bibliographies from the principal investigator groups of the Apollo Telescope Mount (Skylab solar observatory facility) are presented. The publications listed are divided into the following categories: (1) journal publications, (2) journal publications submitted, (3) other publications, (4) presentations - national and international meetings; and (5) other presentations.

  16. 78 FR 938 - Notification of a Public Meeting and a Public Teleconference of the Clean Air Scientific Advisory...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-07

    ... Committee Lead Review Panel AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: The EPA... Clean Air Scientific Advisory Committee (CASAC) Lead Review Panel to conduct a peer review of EPA's Integrated Science Assessment for Lead (Third External Review Draft--November 2012) and EPA's...

  17. Does a research group increase impact on the scientific community or general public discussion? Alternative metric-based evaluation.

    PubMed

    De Gregori, Manuela; Scotti, Valeria; De Silvestri, Annalisa; Curti, Moreno; Fanelli, Guido; Allegri, Massimo; Schatman, Michael E

    2016-01-01

    In this study, we investigated the impact of scientific publications of the Italian SIMPAR (Study In Multidisciplinary PAin Research) group by using altmetrics, defined as nontraditional metrics constituting an alternative to more traditional citation-impact metrics, such as impact factor and H-index. By correlating traditional and alternative metrics, we attempted to verify whether publications by the SIMPAR group collectively had more impact than those performed by its individual members, either in solo publications or in publications coauthored by non-SIMPAR group investigators (which for the purpose of this study we will refer to as "individual publications"). For all the 12 members of the group analyzed (pain therapists, biologists, and pharmacologists), we created Open Researcher and Contributor ID and Impact Story accounts, and synchronized these data. Manually, we calculated the level metrics for each article by dividing the data obtained from the research community by those obtained from the public community. We analyzed 759 articles, 18 of which were published by the SIMPAR group. Altmetrics demonstrated that SIMPAR group publications were more likely to be saved (77.8% vs 45.9%), discussed (61.1% vs 1.1%, P<0.0001), and publicly viewed (11.1% vs 1.3%, P=0.05) than individual publications. These results support the importance of multidisciplinary research groups in the impact of scientific literature; the interaction and synergy among the research participants allowed the obtainment of high impact-literature in the field of personalized pain medicine. Finally, our findings demonstrate the potential of altmetrics in estimating the value of the research products of a group. PMID:27358575

  18. 77 FR 1677 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-11

    ...There will be a 2-day meeting of the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review Methods for Efficacy Testing of Bed Bug Pesticide...

  19. 76 FR 71023 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-16

    ...There will be a 3-day meeting of the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review Common Effects Assessment Methodology developed in the Office of Pesticide Programs and Office of...

  20. Does a research group increase impact on the scientific community or general public discussion? Alternative metric-based evaluation

    PubMed Central

    De Gregori, Manuela; Scotti, Valeria; De Silvestri, Annalisa; Curti, Moreno; Fanelli, Guido; Allegri, Massimo; Schatman, Michael E

    2016-01-01

    In this study, we investigated the impact of scientific publications of the Italian SIMPAR (Study In Multidisciplinary PAin Research) group by using altmetrics, defined as nontraditional metrics constituting an alternative to more traditional citation-impact metrics, such as impact factor and H-index. By correlating traditional and alternative metrics, we attempted to verify whether publications by the SIMPAR group collectively had more impact than those performed by its individual members, either in solo publications or in publications coauthored by non-SIMPAR group investigators (which for the purpose of this study we will refer to as “individual publications”). For all the 12 members of the group analyzed (pain therapists, biologists, and pharmacologists), we created Open Researcher and Contributor ID and Impact Story accounts, and synchronized these data. Manually, we calculated the level metrics for each article by dividing the data obtained from the research community by those obtained from the public community. We analyzed 759 articles, 18 of which were published by the SIMPAR group. Altmetrics demonstrated that SIMPAR group publications were more likely to be saved (77.8% vs 45.9%), discussed (61.1% vs 1.1%, P<0.0001), and publicly viewed (11.1% vs 1.3%, P=0.05) than individual publications. These results support the importance of multidisciplinary research groups in the impact of scientific literature; the interaction and synergy among the research participants allowed the obtainment of high impact-literature in the field of personalized pain medicine. Finally, our findings demonstrate the potential of altmetrics in estimating the value of the research products of a group. PMID:27358575

  1. Apollo telescope mount: A partial listing of scientific publications and presentations

    NASA Technical Reports Server (NTRS)

    Reynolds, J. M. (Editor); Snoddy, W. C. (Editor)

    1976-01-01

    A compilation of bibliographies from the principal investigator groups of the Apollo Telescope Mount (Skylab solar observatory facility) which gathered data from May 28, 1973, to February 8, 1974 is presented. The analysis of these data is presently under way and is expected to continue for several years. The publications listed are divided into the following categories: (1) Journal Publications, (2) Journal Publications Submitted, (3) Other Publications, (4) Presentations - National International Meetings, and (5) Other Presentations. An author index is also included.

  2. Apollo telescope mount: A partial listing of scientific publications and presentations, supplement 3

    NASA Technical Reports Server (NTRS)

    Reynolds, J. M. (Editor); Fields, S. A. (Editor); Snoddy, W. C. (Editor)

    1979-01-01

    Compilations of bibliographies from the principal investigator groups of the Skylab solar observatory facility that gathered data from May 28, 1973, to February 8, 1974 are presented. The analysis of these data is presently under way. The publications listed are divided into the following categories: (1) journal publications; (2) journal publications submitted; (3) other publications; (4) presentations-national and international meetings; and (5) other presentations.

  3. 78 FR 56235 - Board of Scientific Counselors, Office of Public Health Preparedness and Response, (BSC, OPHPR)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-12

    ... Public Health Preparedness and Response, (BSC, OPHPR) In accordance with section 10(a)(2) of the Federal... Director, Centers for Disease Control and Prevention (CDC), and the Director, Office of Public Health... Science and Public Health Practice, Executive Assistant, Centers for Disease Control and Prevention,...

  4. 78 FR 15369 - Board of Scientific Counselors, Office of Public Health Preparedness and Response (BSC, OPHPR)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-11

    ... Public Health Preparedness and Response (BSC, OPHPR) In accordance with section 10(a)(2) of the Federal..., Office of Public Health Preparedness and Response (OPHPR), concerning strategies and goals for the... following topics: Public Health Preparedness and Response Policy Updates; improving critical...

  5. 77 FR 14783 - Notification of a Public Meeting and Two Public Teleconferences for the Clean Air Scientific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ...) Lead Review Panel to conduct a peer review of EPA's Integrated Science Assessment for Lead (Second... CASAC Lead Review Panel will hold a face-to-face public meeting to peer review EPA's second external... Advisory Committee's Review of EPA's Integrated Science Assessment for Lead AGENCY:...

  6. Apollo telescope mount: A partial listing of scientific publications, supplement 2

    NASA Technical Reports Server (NTRS)

    Reynolds, J. M. (Editor); Snoddy, W. C. (Editor)

    1978-01-01

    Reports are compilations of bibliographies from the principal investigator groups of the Apollo Telescope Mount (Skylab solar observatory facility) that gathered data from May 28, 1973, to February 8, 1974. The analysis of these data is presently under way and is expected to continue for several years. The publications listed in this report are divided into the following categories: (1) Journal Publications, (2) Journal Publications Submitted, (3) Other Publications, (4) Presentations--National and International Meetings, and (5) Other Presentations. An author index is included together with errata for the first report.

  7. Scientific Fraud.

    ERIC Educational Resources Information Center

    Goodstein, David

    1991-01-01

    A discussion of fraud in the presentation of results of scientific research cites cases looks at variations in the degree of misrepresentation, kinds and intents of fraud, attention given by public agencies (National Institutes of Health, National Science Foundation, Public Health Service), and differences between scientific and civil fraud. (MSE)

  8. 75 FR 56101 - FIFRA Scientific Advisory Panel; Notice of Rescheduled Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ...The Agency is issuing this notice to reschedule the 3-day meeting of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) Scientific Advisory Panel (SAP) to consider and review the Chlorpyrifos Physiologically Based Pharmacokinetic/Pharmacodynamic (PBPK/PD) Modeling linked to the Cumulative and Aggregate Risk Evaluation System (CARES). The meeting, originally scheduled for October......

  9. 78 FR 68439 - FIFRA Scientific Advisory Panel; Notice of Rescheduled Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-14

    ... notice was published in the Federal Register on October 28, 2013 (78 FR 64211) (FRL-9902-06). All other information provided in the Federal Register on August 9, 2013 (78 FR 48672) (FRL-9394-3) remains unchanged...) to consider and review, Scientific Uncertainties Associated with Corn Rootworm Resistance...

  10. Bisphenol A (BPA) in food contact materials - new scientific opinion from EFSA regarding public health risk.

    PubMed

    Ćwiek-Ludwicka, Kazimiera

    2015-01-01

    The wide use of bisphenol A (BPA) as a monomer in plastics manufacture or epoxy resins intended for food contact materials (FCM) has triggered numerous concerns due to toxicological findings indicating possible endocrine disrupting properties. This article traces the evolution of the scientific opinions since 1986 when the Tolerable Daily Intake (TDI) for BPA and its specific migration limit (SML) from plastic FCM into food were proposed for the first time by the Scientific Committee for Food (SCF). Resent extensive scientific studies concerning refined data on toxicity and exposure to BPA from food and non-food sources (eg. dust, cosmetics, thermal paper), including the most vulnerable groups of population, allowed the European Food Safety Authority (EFSA) to reduce the TDI of BPA from previously 50 µg/kg bw/day to now 4 µg/kg bw/day. EFSA's latest scientific opinion published in 2015 concludes that basing on the current estimations of total exposure to BPA from dietary and non-dietary sources for infants, children and adolescents is below the temporary TDI of 4 μg/kg bw/day. EFSA has also underlined that BPA poses no health risk at the estimated exposure levels of any population age group, including unborn children and the elderly. However, EFSA has indicated that some data on exposure and toxicological effects still require clarifications. PMID:26656411

  11. 78 FR 27234 - Notification of a Public Teleconference of the Clean Air Scientific Advisory Committee (CASAC...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-09

    ... solicited nominations for the CASAC NO X Primary NAAQS Review Panel on October 17, 2012 (77 FR 63827-63828...); Oxides of Nitrogen Primary NAAQS Review Panel AGENCY: Environmental Protection Agency (EPA). ACTION... the Clean Air Scientific Advisory Committee (CASAC) Oxides of Nitrogen (NO X ) Primary...

  12. Golden rice: scientific, regulatory and public information processes of a genetically modified organism.

    PubMed

    Moghissi, A Alan; Pei, Shiqian; Liu, Yinzuo

    2016-01-01

    Historically, agricultural development evolved in three phases. During the first phase the plants were selected on the basis of the availability of a plant with desirable properties at a specific location. The second phase provided the agricultural community with crossbreeding plants to achieve improvement in agricultural production. The evolution of biological knowledge has provided the ability to genetically engineer (GE) crops, one of the key processes within genetically modified organisms (GMO). This article uses golden rice, a species of transgenic Asian rice which contains a precursor of vitamin A in the edible part of the plant as an example of GE/GMO emphasizing Chinese experience in agricultural evolution. It includes a brief review of agricultural evolution to be followed by a description of golden rice development. Golden rice was created as a humanitarian project and has received positive comments by the scientific community and negative voices from certain environmental groups. In this article, we use the Best Available Science (BAS) Concept and Metrics for Evaluation of Scientific Claims (MESC) derived from it to evaluate claims and counter claims on scientific aspects of golden rice. This article concludes that opposition to golden rice is based on belief rather than any of its scientifically derived nutritional, safety or environmental properties. PMID:25603722

  13. Analysis of Research Collaboration between Universities and Private Companies in Spain Based on Joint Scientific Publications

    ERIC Educational Resources Information Center

    Olmeda-Gómez, Carlos; Ovalle-Perandones, María Antonia; de Moya-Anegón, Félix

    2015-01-01

    Introduction: The article presents the results of a study on scientific collaboration between Spanish universities and private enterprise, measured in terms of the co-authorship of papers published in international journals. Method: Bibliometric analysis of papers published in journals listed in Scopus in 2003-2011. Indicators were calculated for…

  14. 76 FR 37356 - 2011 Scientific Meeting of the National Antimicrobial Resistance Monitoring System; Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-27

    ... Resistance Monitoring System; Public Meeting; Request for Comments AGENCY: Food and Drug Administration, HHS... Monitoring System.'' The topic to be discussed is animal and retail sampling methods for the National Antimicrobial Resistance Monitoring System (NARMS). Date and Time: The public meeting will be held on July...

  15. 76 FR 18221 - Board of Scientific Counselors, Office of Public Health Preparedness and Response (BSC, OPHPR)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ... Public Health Preparedness and Response (BSC, OPHPR) In accordance with section 10 (a) (2) of the Federal... Disease Control and Prevention (CDC), and the Director, Office of Public Health Preparedness and Response... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  16. 77 FR 37410 - Board of Scientific Counselors, Office of Public Health Preparedness and Response; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-21

    ... Public Health Preparedness and Response; Meeting In accordance with section 10 (a) (2) of the Federal... Prevention (CDC), and the Director, Office of Public Health Preparedness and Response (OPHPR), concerning... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  17. 77 FR 20823 - Board of Scientific Counselors, Office of Public Health Preparedness and Response (BSC, OPHPR)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-06

    ... Public Health Preparedness and Response (BSC, OPHPR) In accordance with section 10(a)(2) of the Federal... Disease Control and Prevention (CDC), and the Director, Office of Public Health Preparedness and Response... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH...

  18. 76 FR 76416 - Board of Scientific Counselors, Office of Public Health Preparedness and Response (BSC, OPHPR)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ... Public Health Preparedness and Response (BSC, OPHPR) In accordance with section 10(a)(2) of the Federal... Disease Control and Prevention (CDC), and the Director, Office of Public Health Preparedness and Response... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  19. 76 FR 53474 - Board of Scientific Counselors, Office of Public Health Preparedness and Response (BSC, OPHPR)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... Public Health Preparedness and Response (BSC, OPHPR) In accordance with section 10 (a)(2) of the Federal..., Office of Public Health Preparedness and Response (OPHPR), concerning strategies and goals for the... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  20. [Generalists or Specialists? Interdisciplinarity in, and Scientific Development of, Public Health in Germany].

    PubMed

    Razum, O; Dockweiler, C

    2015-11-01

    Interdisciplinarity is not only a constitutive element of public health; it also contributes significantly to the solution of complex public health problems. Only through the cooperation of different disciplines and professions can the diverse social and methodological-technical challenges of developing, implementing and evaluating health-related interventions be solved. In this context, public health in Germany is facing challenges in its further development, two of which we discuss here. Firstly, there is a gap between aspiration and reality of interdisciplinary research and teaching of public health. Secondly, related to that, there is an increasingly difficult balance between professional breadth and specialisation in the university education of future public health experts. PMID:25643291

  1. Pitfalls in archaeoastronomy: with examples from Mesoamerica.

    NASA Astrophysics Data System (ADS)

    Köhler, U.

    The kinds of pitfalls to be treated in this paper have been grouped into three categories: uncritical postulation of astronomical links, overinterpretation of alignments, and ethnocentric application of recent European concepts of space and time.

  2. Calibrated fair measure of particle physics publications: indices to quantify an individual's scientific research output

    NASA Astrophysics Data System (ADS)

    Tawfik, A.

    2015-07-01

    Are existing ways of measuring scientific quality reflecting disadvantages of not being part of giant collaborations? How could possible discrimination be avoided? We propose indices defined for each discipline (subfield) and which count the plausible contributions added up by collaborators maintaining the spirit of interdependency. Based on the growing debate about defining potential biases and detecting unethical behavior, a standardized method to measure contributions of the astronomical number of coauthors is introduced.

  3. 75 FR 16817 - 2010 Scientific Meeting of the National Antimicrobial Resistance Monitoring System; Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

    ... for Veterinary Medicine (HFV- 12), Food and Drug Administration, 7519 Standish Pl., Rockville, MD... the day of the public meeting will be provided on a space available basis beginning at 8 a.m. on...

  4. Bibliography of scientific publications and presentations relating to planetary quarantine: 1966 - 1971

    NASA Technical Reports Server (NTRS)

    Bradley, F. D.; Nadel, M. R.

    1973-01-01

    A bibliography, which is a compilation of citations relating to planetary quarantine, previously listed in similar publications since 1967, is presented to provide a reference for reviewing planetary quarantine research and development.

  5. Scientific publications in pediatrics over the last ten years in Turkey and worldwide.

    PubMed

    Altun, Demet; Dabak, Orçun; Hacıhamdioğlu, Duygu Övünç

    2015-01-01

    In keeping with the large area of interest comprised within the field of pediatrics, the number and diversity of publications in this field has gradually increased over the last ten years in our country as well as worldwide. The objective of this paper is to offer an analysis of the status of pediatrics publications during those ten years. The publications analyzed were listed in the Thomson Reuters Web of Science and/or published in journals included in the Science Citation Index, the Science Citation Index Expanded and the Social Sciences Citation Index. All of these publications appeared in journals in which at least one pediatrics specialist published between the years 2004 and 2013. It may be seen that Turkey is in fifth place worldwide in terms of the number of studies published in these journals, with 6,134 such publications. The conclusion is that it is necessary for more Turkish studies to be multicenter, to involve international participation and to receive more citations; importance must be attached to the objective of transforming of the knowledge produced by Turkish researchers into a greater number of publications of increased quality. PMID:26690590

  6. [Modern aspects of combat maxillofacial trauma (review of foreign scientific-medical publications during 2012-2013)].

    PubMed

    Grebnev, G A; Bolekhan, V N; Golota, A S; Ivchenko, E V; Krassiĭ, A B; Nagibovich, O A; Parfenov, V D; Rezvantsev, M V

    2013-04-01

    The current article is dedicated to the modern aspects of combat maxillofacial trauma as they have been presented in 2012-2013 scientific publications. It has been shown that due to employment of more and more powerful explosive devices the facial trauma over the last decade has occurred more frequently and become more severe. Some new methods of facial injuries treatment are being tested now, among them KSL-W antimicrobial decapeptide, new bone regenerative biocompatible materials, scar-healing mesenchymal and adipose-derived stem cells, and a custom automated face dressing platform. PMID:24000612

  7. Hubble Space Telescope - Scientific, Technological and Social Contributions to the Public Discourse on Science

    NASA Technical Reports Server (NTRS)

    Wiseman, Jennifer

    2012-01-01

    The Hubble Space Telescope has unified the world with a sense of awe and wonder for 2 I years and is currently more scientifically powerful than ever. I will present highlights of discoveries made with the Hubble Space Telescope, including details of planetary weather, star formation, extra-solar planets, colliding galaxies, and a universe expanding with the acceleration of dark energy. I will also present the unique technical challenges and triumphs of this phenomenal observatory, and discuss how our discoveries in the cosmos affect our sense of human unity, significance, and wonder.

  8. Who's the Boss?: The Possibilities and Pitfalls of Collaborative Administration for Untenured WPAs.

    ERIC Educational Resources Information Center

    Schell, Eileen E.

    1998-01-01

    Analyzes scholarship on administrative leadership styles. Describes the writing program co-directorship model the author and a colleague developed at a Southern public university, and offers a critical analysis of both the possibilities and pitfalls of collaborative administration for untenured writing program administrators. Points out ways in…

  9. Scientific publications in nursing journals from Mainland China, Taiwan, and Hong Kong: a 10-year survey of the literature

    PubMed Central

    Yang, Li

    2016-01-01

    Background: China has witnessed remarkable progress in scientific performance in recent years. However, the quantity and quality of nursing publications from three major regions (Mainland China, Taiwan, and Hong Kong) have not been reported. This study aimed to investigate the characteristics of scientific research productivity from Mainland China, Taiwan, and Hong Kong in the field of nursing. Methods: Articles published in the 110 nursing journals originating from Mainland China, Taiwan, and Hong Kong between 2005 and 2014 were retrieved from the Web of Science. The total number of articles published, the impact factor, and the citation count were analyzed. Results: There were 2,439 publications between 2005 and 2014 from China, including 438 from Mainland China, 1,506 from Taiwan, and 495 from Hong Kong. There was a significant increase in publications for these three regions (p < 0.05), especially for Mainland China, with a 59.50-fold increase experienced. From 2011, the number of publications from Mainland China exceeded that from Hong Kong. Taiwan had the highest total journal impact factor (2,142.81), followed by Hong Kong (720.39) and Mainland China (583.94). The mean journal impact factor from Hong Kong (1.46) was higher than that from Taiwan (1.42) and Mainland China (1.33). Taiwan had the highest total citation count (8,392), followed by Hong Kong (3,785) and Mainland China (1,493). The mean citation count from Hong Kong (7.65) was higher than that from Taiwan (5.57) and Mainland China (3.41). The Journal of Clinical Nursing was the most popular journal in the three regions. Discussion: Chinese contributions to the field of nursing have significantly increased in the past ten years, particularly from Mainland China. Taiwan is the most productive region in China. Hong Kong had the highest-quality research output, according to mean journal impact factor and mean citation count. PMID:26989631

  10. Conflicting stories about public scientific controversies: Effects of news convergence and divergence on scientists' credibility.

    PubMed

    Jensen, Jakob D; Hurley, Ryan J

    2012-08-01

    Surveys suggest that approximately one third of news consumers have encountered conflicting reports of the same information. News coverage of science is especially prone to conflict, but how news consumers perceive this situation is currently unknown. College students (N = 242) participated in a lab experiment where they were exposed to news coverage about one of two scientific controversies in the United States: dioxin in sewage sludge or the reintroduction of gray wolves to populated areas. Participants received (a) one news article (control), (b) two news articles that were consistent (convergent), or (c) two news articles that conflicted (divergent). The effects of divergence induced uncertainty differed by news story. Greater uncertainty was associated with increased scientists' credibility ratings for those reading dioxin regulation articles and decreased scientists' credibility ratings for those reading wolf reintroduction articles. Unlike other manifestations of uncertainty in scientific discourse, conflicting stories seem to generate effects that vary significantly by topic. Consistent with uncertainty management theory, uncertainty is embraced or rejected by situation. PMID:23832155

  11. New linked data on research investments: scientific workforce, productivity, and public value

    PubMed Central

    Lane, Julia; Owen-Smith, Jason; Rosen, Rebecca; Weinberg, Bruce

    2015-01-01

    Longitudinal micro-data derived from transaction level information about wage and vendor payments made by federal grants on multiple U.S. campuses are being developed in a partnership involving researchers, university administrators, representatives of federal agencies, and others. This paper describes the UMETRICS data initiative that has been implemented under the auspices of the Committee on Institutional Cooperation. The resulting data set reflects an emerging conceptual framework for analyzing the process, products, and impact of research. It grows from and engages the work of a diverse and vibrant community. This paper situates the UMETRICS effort in the context of research evaluation and ongoing data infrastructure efforts in order to highlight its novel and valuable features. Refocusing data construction in this field around individuals, networks, and teams offers dramatic possibilities for data linkage, the evaluation of research investments, and the development of rigorous conceptual and empirical models. Two preliminary analyses of the scientific workforce and network approaches to characterizing scientific teams ground a discussion of future directions and a call for increased community engagement. PMID:26335785

  12. Seabird databases and the new paradigm for scientific publication and attribution

    USGS Publications Warehouse

    Hatch, Scott A.

    2010-01-01

    For more than 300 years, the peer-reviewed journal article has been the principal medium for packaging and delivering scientific data. With new tools for managing digital data, a new paradigm is emerging—one that demands open and direct access to data and that enables and rewards a broad-based approach to scientific questions. Ground-breaking papers in the future will increasingly be those that creatively mine and synthesize vast stores of data available on the Internet. This is especially true for conservation science, in which essential data can be readily captured in standard record formats. For seabird professionals, a number of globally shared databases are in the offing, or should be. These databases will capture the salient results of inventories and monitoring, pelagic surveys, diet studies, and telemetry. A number of real or perceived barriers to data sharing exist, but none is insurmountable. Our discipline should take an important stride now by adopting a specially designed markup language for annotating and sharing seabird data.

  13. 77 FR 64334 - Notification of a Public Teleconference of the Clean Air Scientific Advisory Committee (CASAC...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-19

    ... Panel held a face-to- face meeting on September 11-13, 2012 (as noticed in 77 FR 46755-46756) to review...) Ozone Review Panel AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: The EPA Science Advisory Board (SAB) Staff Office announces a public teleconference of the CASAC Ozone...

  14. 76 FR 51365 - Notification of a Public Teleconference of the Clean Air Scientific Advisory Committee (CASAC...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-18

    .... The Lead Review Panel held a face-to-face meeting on July 20-21, 2011 (as noticed in 76 FR 36120-36121...) Lead Review Panel AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: The EPA Science Advisory Board (SAB) Staff Office announces a public teleconference of the CASAC Lead Review...

  15. Public Communication of Science in Blogs: Recontextualizing Scientific Discourse for a Diversified Audience

    ERIC Educational Resources Information Center

    Luzón, María José

    2013-01-01

    New media are having a significant impact on science communication, both on the way scientists communicate with peers and on the dissemination of science to the lay public. Science blogs, in particular, provide an open space for science communication, where a diverse audience (with different degrees of expertise) may have access to science…

  16. Citizen Groups and Scientific Decisionmaking: Does Public Participation Influence Environmental Outcomes?

    ERIC Educational Resources Information Center

    Daley, Dorothy M.

    2007-01-01

    This paper explores the influence of local community groups on agency decisionmaking at hazardous waste sites nationwide. The central purpose of this research is to examine the relative influence of two forms of public participation at Superfund sites: Community Advisory Groups (CAGs) and Technical Assistance Grants (TAGs). When citizens mobilize…

  17. Managing scientific complexity in public policy: the case of U.S. climate change legislation in the 111th Congress

    NASA Astrophysics Data System (ADS)

    Mueller, J. A.; Runci, P. J.

    2009-12-01

    The recent passage of the American Climate and Energy Security Act by the U.S. House of Representatives in June of this year was a landmark in U.S. efforts to move climate change legislation through Congress. Although an historic achievement, the bill (and surrounding debate) highlights many concerns about the processes by which lawmakers and the public inform themselves about scientifically relevant problems and, subsequently, by which policy responses are crafted in a context of complexity, uncertainty, and competition for resources and attention. In light of the ever-increasing specialization of expertise in the sciences and other technical fields, and the inherent complexity of scientifically relevant problems such as climate change, society faces significant hurdles in its efforts to integrate knowledge and develop sufficient understanding of these problems to which it must respond with legislation or other effective collective or individual action. The emergence of a new class of experts who act as science-policy brokers may not be sufficient to cross these hurdles. Herein, we explore how society and the scientific community in particular can work toward closing the ever-growing gap between technical knowledge and society’s ability to comprehend and use it. Both authors are currently legislative fellows working on energy and climate change issues in the U.S. Senate.

  18. Smart Sensors: Advantages and Pitfalls

    NASA Astrophysics Data System (ADS)

    French, Paddy James

    For almost 50 years, silicon sensors have been on the market. There have been many examples of success stories for simple silicon sensors, such as the Hall plate and photo-diode. These have found mass-market applications. The development of micromachining techniques brought pressure sensors and accelerometers into the market and later the gyroscope. These have also achieved mass-market. The remaining issue is how far to integrate. Many of the devices on the market use a simple sensor with external electronics or read-out electronics in the same package (system-in-a-package). However, there are also many examples of fully integrated sensors (smart sensors) where the whole system is integrated into a single chip. If the application and the device technology permit this, there can be many advantages. A broader look at sensors shows a wealth of integrated devices. The critical issues are reliability and packaging if these devices are to find the applications. A number of silicon sensors and actuators have shown great commercial success, but still many more have to find their way out of the laboratory. This paper will examine the development of the technologies, some of the success stories and the opportunities for integrated Microsystems as well as the pitfalls.

  19. Public Private Partnerships, Corporate Welfare or Building the Nation's Scientific Infrastructure?

    NASA Astrophysics Data System (ADS)

    Shank, C. V.

    1996-03-01

    A debate is taking place in the U.S. concerning the investment of scarce Federal funds in science and technology research. Clouding this discussion is the proliferation of extreme views illustrated in the title of this talk. The impacts of the end of the cold war, the globalization of the economy and the realities of the budget deficit create a situation that cries out for a new social contract between scientists and taxpayers. We need to examine the successes and failures of the last 50 years to form the basis for a set of principles to enable the creation of a new consensus to define the roles of industry, government, universities and national laboratories in the research enterprise. The scientific infrastructure, and by extension, the economic vitality of the U.S., are at risk.

  20. [Pneumonia awareness year, 2004: scientific impact through publications in Archivos de Bronconeumología].

    PubMed

    Rajas Naranjo, Olga; Aspa Marco, Javier

    2006-10-01

    Pneumonia is a common and potentially serious infectious disease. Morbidity and mortality rates continue to be high in spite of major advances and steady progress in diagnosis and treatment. The economic impact of the disease is also great. It is therefore necessary to enlist the public, primary care and emergency physicians, and public policy administrators to join forces to treat and prevent pneumonia for the common good. The annual incidence of pneumonia in the population over the age of 14 years is 1.6 to 2.6 episodes/1000 inhabitants. The mortality rate is 14.1 per 100,000 inhabitants, and the associated costs are 115 million euros annually. The RESPIRA Foundation and the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) declared 2004 to be pneumonia awareness year with the aim of coordinating efforts to raise awareness, distribute information, and foster debate. PMID:17067522

  1. Contemporary Cuban Physics Through Scientific Publications: An Insider’s View

    NASA Astrophysics Data System (ADS)

    Altshuler, Ernesto

    In a previous paper, the author reached some conclusions on the tendencies of the publications by Cuban physicists in international journals (Altshuler, Rev Cub Fís 22(2):173-182, 2005) and called for a systematic bibliometric study of the subject. Such a study has now been undertaken (a contribution to this volume entitled "Physics in Cuba from the Perspective of Bibliometrics" by Werner Marx and Manuel Cardona, referred to in this paper as Marx and Cardona) and supports the main conclusions of the former work. The scenario of Cuban physics since 1995 has been conditioned by two main facts interacting in a nontrivial way: the serious material shortages affecting local physics laboratories and bibliographic resources, and an increase in the country's international collaboration. As a positive result, the total volume of Cuban publications in international physics journals has increased since 1995, perhaps reaching a peak around the year 2000, while the number of citations of Cuban papers and the impact of the journals in which they were published have continued to increase since the mid-1990s. Theoretical work produced by physicists from a number of Cuban institutions in international collaborations strongly contribute to those numbers. In the last years, international publications suggest a `self-organized' opening of Cuban physics towards interdisciplinary subjects, which is increasing the `bibliometric visibility' of autochthonous experimental work.

  2. Bibliometric analysis of scientific publications on waterpipe (narghile, shisha, hookah) tobacco smoking during the period 2003-2012

    PubMed Central

    2014-01-01

    Background Waterpipe tobacco smoking has spread worldwide. However, the evaluation of scientific output in the field of waterpipe tobacco smoking has not been studied yet. The main objectives of this study were to analyze worldwide research output in the waterpipe tobacco smoking field, and to examine the authorship pattern and the citations retrieved from the Scopus database for over a decade. Methods Data from January 1, 2003 through December 31, 2012 were searched for documents with specific words regarding waterpipe tobacco smoking as “keywords” in the title. Scientific output was evaluated based on a methodology developed and used in other bibliometric studies: (a) total and trends of contributions in waterpipe tobacco smoking research between 2003 and 2012; (b) authorship patterns and research productivity; (c) collaboration patterns; (d) the citations received by the publications; and (e) areas of interest of the published papers. Results Worldwide there were 334 publications that met the criteria during the study period. The largest number of publications in waterpipe tobacco smoking were from the United States of America (USA) (33.5%), followed by Lebanon (15.3%), and France (10.5%). The total number of citations at the time of data analysis (October 18, 2013) was 4,352, with an average of 13 citations per document and a median (interquartile range) of 4.0 (1.0–16.0). The h-index of the retrieved documents was 34. The highest h-index by country was 27 for the USA, followed by 20 for Syrian Arab Republic and Lebanon. Conclusions The present data reveal a promising rise and a good start for research activity in the field of waterpipe tobacco smoking. More effort is needed to bridge the gap in waterpipe smoking-based research and to promote better evaluation of waterpipe smoking, risks, health effects, or control services worldwide. PMID:24725483

  3. Legalization, decriminalization & medicinal use of cannabis: a scientific and public health perspective.

    PubMed

    Svrakic, Dragan M; Lustman, Patrick J; Mallya, Ashok; Lynn, Taylor Andrea; Finney, Rhonda; Svrakic, Neda M

    2012-01-01

    Empirical and clinical studies clearly demonstrate significant adverse effects of cannabis smoking on physical and mental health as well as its interference with social and occupational functioning. These negative data far outweigh a few documented benefits for a limited set of medical indications, for which safe and effective alternative treatments are readily available. If there is any medical role for cannabinoid drugs, it lies with chemically defined compounds, not with unprocessed cannabis plant. Legalization or medical use of smoked cannabis is likely to impose significant public health risks, including an increased risk of schizophrenia, psychosis, and other forms of substance use disorders. PMID:22675784

  4. Byssinosis: a role for public health in the face of scientific uncertainty.

    PubMed Central

    Wegman, D H; Levenstein, C; Greaves, I A

    1983-01-01

    Byssinosis, a lung disease caused by cotton dust, has been the subject of recent controversy. Debates over the nature of the disease, possible interactions with cigarette smoking, and the proposed reevaluation of the cotton dust standard by the Occupational Safety and Health Administration have tended to overlook the plight of affected workers and to obscure the most effective means for preventing the disease. The present lack of definitive information is no reason for inaction, nor for depriving disabled workers of adequate financial compensation. In this respect, byssinosis is no different from other public health hazards for which action must often be taken on the basis of incomplete evidence. PMID:6217757

  5. Byssinosis: a role for public health in the face of scientific uncertainty.

    PubMed

    Wegman, D H; Levenstein, C; Greaves, I A

    1983-02-01

    Byssinosis, a lung disease caused by cotton dust, has been the subject of recent controversy. Debates over the nature of the disease, possible interactions with cigarette smoking, and the proposed reevaluation of the cotton dust standard by the Occupational Safety and Health Administration have tended to overlook the plight of affected workers and to obscure the most effective means for preventing the disease. The present lack of definitive information is no reason for inaction, nor for depriving disabled workers of adequate financial compensation. In this respect, byssinosis is no different from other public health hazards for which action must often be taken on the basis of incomplete evidence. PMID:6217757

  6. [Qualitative dimensions of the scientific, technological and innovation production at Public Health].

    PubMed

    Luz, Madel Therezinha; Mattos, Rafael da Silva

    2010-07-01

    This article shows the results of a qualitative evaluation on the expansion of the Collective Health area according with the production of the triennial Collective Health Congresses Annals which happen between 1997 to 2006, promoted by Abrasco - Brazilian Association of Collective Health. The specific objective was to estimate the growth of importance of the area in the scientific as well as in the social Brazilian scenario in the last decennary through the analysis of aspects and substantive dimensions. The methodological strategy of the study was to consider the complexity and data profusion referred to the dimensions of this multidisciplinary field (more and more interdisciplinary) of knowledge and intervention. From this perspective, analysis and interpretations of document sources were done, applying theoretical, methodological and analytical referential of the social science and X statistics techniques. It could be observed that: (1) in the last decade, the Collective Health area expanded into its three subareas (Epidemiology, Planning/Management and Health Services and, Human Sciences); (2) there is a tendency of more interactivity among the programs and with their communities and the institutions; (3) there is a growth in the quantity of authors writing about the field and different authors by article; (4) it is being elaborated a big internal specialization into the subareas. PMID:20694318

  7. Challenging Expertise: Paul Feyerabend vs. Harry Collins & Robert Evans on democracy, public participation and scientific authority: Paul Feyerabend vs. Harry Collins & Robert Evans on scientific authority and public participation.

    PubMed

    Sorgner, Helene

    2016-06-01

    This paper compares Feyerabend's arguments in Science in a Free Society to the controversial theory of expertise proposed by Harry Collins and Robert Evans as a Third Wave of Science Studies. Is the legitimacy of democratic decisions threatened by the unquestioned authority of scientific advice? Or does, on the contrary, science need protection from too much democratic participation in technical decisions? Where Feyerabend's political relativism envisions democratic society as inherently pluralist and demands equal contribution of all traditions and worldviews to public decision-making, Collins and Evans hold a conception of elective modernism, defending the reality and value of technical expertise and arguing that science deserves a privileged status in modern democracies, because scientific values are also democratic values. I will argue that Feyerabend's political relativism provides a valuable framework for the evaluation of Collins' and Evans' theory of expertise. By constructing a dialog between Feyerabend and this more recent approach in Science and Technology Studies, the aim of this article is not only to show where the two positions differ and in what way they might be reconciled, but also how Feyerabend's philosophy provides substantial input to contemporary debate. PMID:27269270

  8. Public Understanding of Science as Seen by the Scientific Community: Do We Need To Re-Conceptualize the Challenge and To Re-Examine Our Own Assumptions?

    ERIC Educational Resources Information Center

    Cobern, William W.

    This paper addresses the question of how the scientific community views the public understanding of science and whether there needs to be a re-conceptualization of the challenge to foster the public understanding of science, as well as whether there is a need to re-examine assumptions. It is argued that the science community's historic perspective…

  9. The Scientific Field during Argentina's Latest Military Dictatorship (1976-1983): Contraction of Public Universities and Expansion of the National Council for Scientific and Technological Research (CONICET)

    ERIC Educational Resources Information Center

    Bekerman, Fabiana

    2013-01-01

    This study looks at some of the traits that characterized Argentina's scientific and university policies under the military regime that spanned from 1976 through 1983. To this end, it delves into a rarely explored empirical observation: financial resource transfers from national universities to the National Scientific and Technological Research…

  10. Science Concierge: A Fast Content-Based Recommendation System for Scientific Publications.

    PubMed

    Achakulvisut, Titipat; Acuna, Daniel E; Ruangrong, Tulakan; Kording, Konrad

    2016-01-01

    Finding relevant publications is important for scientists who have to cope with exponentially increasing numbers of scholarly material. Algorithms can help with this task as they help for music, movie, and product recommendations. However, we know little about the performance of these algorithms with scholarly material. Here, we develop an algorithm, and an accompanying Python library, that implements a recommendation system based on the content of articles. Design principles are to adapt to new content, provide near-real time suggestions, and be open source. We tested the library on 15K posters from the Society of Neuroscience Conference 2015. Human curated topics are used to cross validate parameters in the algorithm and produce a similarity metric that maximally correlates with human judgments. We show that our algorithm significantly outperformed suggestions based on keywords. The work presented here promises to make the exploration of scholarly material faster and more accurate. PMID:27383424

  11. The role of scientific knowledge in shaping public attitudes to GM technologies.

    PubMed

    Mielby, Henrik; Sandøe, Peter; Lassen, Jesper

    2013-02-01

    Depending on the perceived balance of risk and benefit, and on the perceived unnaturalness, some applications of gene technology appear more acceptable to the public than others. This study asks whether a person's knowledge of biology affects their assessment of these factors differently. A random sample of the Danish population (n = 2000) was presented with questionnaires. The respondent's knowledge was measured by a number of textbook questions on biology. The results indicated that knowledge increases the likelihood that a person will have differentiated opinions on medical and agricultural applications, but decreases the likelihood that he or she will differentiate between cisgenic and transgenic cereals. We discuss the implication that knowledge makes people more likely to base their acceptance on judgements of risks and benefits, rather than on judgements of naturalness. The article concludes that the effect of knowledge on acceptance cannot be generalised wholesale from one application, or method, to others. PMID:23833022

  12. Scientific advice and public policy: expert advisers' and policymakers' discourses on boundary work.

    PubMed

    Hoppe, Robert

    2009-08-01

    This article reports on considerable variety and diversity among discourses on their own jobs of boundary workers of several major Dutch institutes for science-based policy advice. Except for enlightenment, all types of boundary arrangements/work in the Wittrock-typology (Social knowledge and public policy: eight models of interaction. In: Wagner P (ed) Social sciences and modern states: national experiences and theoretical crossroads. Cambridge University Press, Cambridge, 1991) do occur. 'Divergers' experience a gap between science and politics/policymaking; and it is their self-evident task to act as a bridge. They spread over four discourses: 'rational facilitators', 'knowledge brokers', 'megapolicy strategists', and 'policy analysts'. Others aspire to 'convergence'; they believe science and politics ought to be natural allies in preparing collective decisions. But 'policy advisors' excepted, 'postnormalists' and 'deliberative proceduralists' find this very hard to achieve. PMID:19655051

  13. Firearms injuries and deaths: a critical public health issue. American Medical Association Council on Scientific Affairs.

    PubMed Central

    1989-01-01

    The prevention of firearm deaths and injuries is one of the most complex and controversial issues facing the public health profession in recent years. Laws have been enacted to control or discourage private gun ownership, and especially to eliminate guns from the hands of criminals, but the laws' effects in reducing crime and firearm-related injuries and deaths have been disappointing. Gunshot wounds are the 12th leading cause of death in the United States and more than half of all suicides are committed with guns. There are virtually no reliable data on the number of nonfatal firearm injuries. One of the most troubling aspects of handgun violence is that children often are the victims. Educational efforts have been attempted to promote the safer use of firearms, but they have not led to a significant reduction in the number of fatalities, since most firearm incidents are intended to do harm. PMID:2495544

  14. Science Concierge: A Fast Content-Based Recommendation System for Scientific Publications

    PubMed Central

    Achakulvisut, Titipat; Acuna, Daniel E.; Ruangrong, Tulakan; Kording, Konrad

    2016-01-01

    Finding relevant publications is important for scientists who have to cope with exponentially increasing numbers of scholarly material. Algorithms can help with this task as they help for music, movie, and product recommendations. However, we know little about the performance of these algorithms with scholarly material. Here, we develop an algorithm, and an accompanying Python library, that implements a recommendation system based on the content of articles. Design principles are to adapt to new content, provide near-real time suggestions, and be open source. We tested the library on 15K posters from the Society of Neuroscience Conference 2015. Human curated topics are used to cross validate parameters in the algorithm and produce a similarity metric that maximally correlates with human judgments. We show that our algorithm significantly outperformed suggestions based on keywords. The work presented here promises to make the exploration of scholarly material faster and more accurate. PMID:27383424

  15. Current use of medical eponyms – a need for global uniformity in scientific publications

    PubMed Central

    2009-01-01

    Background Although eponyms are widely used in medicine, they arbitrarily alternate between the possessive and nonpossessive forms. As very little is known regarding extent and distribution of this variation, the present study was planned to assess current use of eponymous term taking "Down syndrome" and "Down's syndrome" as an example. Methods This study was carried out in two phases – first phase in 1998 and second phase in 2008. In the first phase, we manually searched the terms "Down syndrome" and "Down's syndrome" in the indexes of 70 medical books, and 46 medical journals. In second phase, we performed PubMed search with both the terms, followed by text-word search for the same. Results In the first phase, there was an overall tilt towards possessive form – 62(53.4%) "Down's syndrome" versus 54(46.6%) "Down syndrome." However, the American publications preferred the nonpossesive form when compared with their European counterpart (40/50 versus 14/66; P < 0.001). In the second phase, PubMed search showed, compared to "Down syndrome," term "Down's syndrome" yielded approximately 5% more articles. The text-word search of both forms between January 1970 and June 2008 showed a gradual shift from "Down's syndrome" to "Down syndrome," and over the last 20 years, the frequency of the former was approximately halved (33.7% versus 16.5%; P < 0.001). The abstracts having possessive form were mostly published from the European countries, while most American publications used nonpossesive form consistently. Conclusion Inconsistency in the use of medical eponyms remains a major problem in literature search. Because of linguistic simplicity and technical advantages, the nonpossessive form should be used uniformly worldwide. PMID:19272131

  16. Examining authentic talk and student authorship of scientific ideas: Public pedagogy and affinity space

    NASA Astrophysics Data System (ADS)

    Slaton, Adriane McNamara

    One of the great challenges to teachers both historically and contemporarily is to facilitate a classroom as a group of students, while concurrently attending to each individual student. As the profession becomes increasingly aware and sensitive to student (dis)abilities, academic giftedness, pressures of athletics and extra-curricular events, and acknowledges the racial, cultural, sexual, economic, gendered identities of students--- the complexity of each individual student becomes ever more apparent. It is a seemingly insurmountable challenge. This dissertation examines how stem cell unit guided group learning while also attending to the individual learning needs of each student. What makes classroom study unusual in research is that it is completely "usual". This study was not part of a university partnership nor did it take place in an affluent school district. Instead, this unit took place in a large, Midwestern urban high school that was/is often written off as a failing---underscoring that powerful science teaching and learning is occurring in schools society simultaneously portrays as victim and villain in the media. Using a sociocultural lens, this ethnographic study draws upon two frameworks, Wenger's communities of practice (1998) and Hayes and Gee's (2011) public pedagogy, to examine how participation in a debate individualizes and personalizes student knowledge and participation in science. The primary use of a community of practice framework allowed for analysis of the norms, rules, practices, and routines of Classroom 507---to establish the nature of the community of learners in the study. A secondary framework, public pedagogy, allowed for deeper understanding of the practices drawn upon in the classroom through consideration of the design, resources, and an emergent "affinity space". This hybridized analysis led to further understanding of how students and teacher stand to learn, participate, engage and use a classroom lesson, the debate, to serve

  17. A semantic-based method for extracting concept definitions from scientific publications: evaluation in the autism phenotype domain

    PubMed Central

    2013-01-01

    Background A variety of informatics approaches have been developed that use information retrieval, NLP and text-mining techniques to identify biomedical concepts and relations within scientific publications or their sentences. These approaches have not typically addressed the challenge of extracting more complex knowledge such as biomedical definitions. In our efforts to facilitate knowledge acquisition of rule-based definitions of autism phenotypes, we have developed a novel semantic-based text-mining approach that can automatically identify such definitions within text. Results Using an existing knowledge base of 156 autism phenotype definitions and an annotated corpus of 26 source articles containing such definitions, we evaluated and compared the average rank of correctly identified rule definition or corresponding rule template using both our semantic-based approach and a standard term-based approach. We examined three separate scenarios: (1) the snippet of text contained a definition already in the knowledge base; (2) the snippet contained an alternative definition for a concept in the knowledge base; and (3) the snippet contained a definition not in the knowledge base. Our semantic-based approach had a higher average rank than the term-based approach for each of the three scenarios (scenario 1: 3.8 vs. 5.0; scenario 2: 2.8 vs. 4.9; and scenario 3: 4.5 vs. 6.2), with each comparison significant at the p-value of 0.05 using the Wilcoxon signed-rank test. Conclusions Our work shows that leveraging existing domain knowledge in the information extraction of biomedical definitions significantly improves the correct identification of such knowledge within sentences. Our method can thus help researchers rapidly acquire knowledge about biomedical definitions that are specified and evolving within an ever-growing corpus of scientific publications. PMID:23937724

  18. [Optimizing French scientific and economic performance: the Cifre system of public-private partnership in doctoral research and Servier's contribution].

    PubMed

    Canet, Emmanuel; Grassy, Gérard

    2006-01-01

    The European Union has set itself the daunting target of becoming the world's most competitive and dynamic knowledge-based economy by 2010. Any hope of success against the United States and the Asian tiger economies lies in the quality of scientific and technological research. In France, postgraduate training has long labored under a deep academia/industry divide. Although the universities have introduced supervised 3 year doctoral courses along the lines of the English-speaking countries, they still produce too many postdocs with little experience or understanding of, and little taste for, the private sector. This ignores career realities: the public sector can offer employment to only half the postdocs it produces. The rest must fall back on positions in the private sector, in some cases with a sense of failure, ill suiting them to drive the intellectual economy forwards compared to their international competitors. To combat the divide and emphasize the quality of the research training available within industry, the public/private National Association for Technical Research (ANRT), acting on behalf of the Ministry of Research, created the Industrial Research Training Agreement (Cifre) scheme in 1981. Higher education laboratories and private companies combine to offer doctoral students the opportunity to undertake their 3 year course in a mixed public/private environment (the exact ratio is not defined but in the case of the Servier Research Group, an early and active participant in the scheme, at least one third of the course is spent in the private sector). The doctoral thesis is thereby transformed into a meaningful career qualification. Funded by the Ministry, with maintenance grants to the students and compensatory payments to the companies, the Cifre scheme, which is currently being expanded, has produced 12,000 postdocs personally and intellectually equipped for careers transiting seamlessly between the public and private sectors, to the enrichment of each

  19. It Ain't (Just) the Heat, It's the Humanity: Increasing Public Understanding of Scientific Consensus and Its Role in Climate Literacy

    NASA Astrophysics Data System (ADS)

    Jacobs, P.; Cook, J.; Nuccitelli, D.

    2014-12-01

    An overwhelming scientific consensus exists on the issue of anthropogenic climate change. Unfortunately, public perception of expert agreement remains low- only around 1 in 10 Americans correctly estimates the actual level of consensus on the topic. Moreover, several recent studies have demonstrated the pivotal role that perceived consensus plays in the public's acceptance of key scientific facts about environmental problems, as well as their willingness to support policy to address them. This "consensus gap", between the high level of scientific agreement vs. the public's perception of it, has led to calls for increased consensus messaging. However this call has been challenged by a number of different groups: climate "skeptics" in denial about the existence and validity of the consensus; some social science researchers and journalists who believe that such messages will be ineffective or counterproductive; and even some scientists and science advocates who downplay the value of consensus in science generally. All of these concerns can be addressed by effectively communicating the role of consensus within science to the public, as well as the conditions under which consensus is likely to be correct. Here, we demonstrate that the scientific consensus on anthropogenic climate change satisfies these conditions, and discuss past examples of purported consensus that failed or succeeded to satisfy them as well. We conclude by discussing the way in which scientific consensus is interpreted by the public, and how consensus messaging can improve climate literacy.

  20. Pitfalls of CITES implementation in Nepal: a policy gap analysis.

    PubMed

    Dongol, Yogesh; Heinen, Joel T

    2012-08-01

    Implementation of policy involves multiple agencies operating at multiple levels in facilitating processes and actions to accomplish desired results. The Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) was developed and implemented to regulate and control international wildlife trade, but violations of the agreement are widespread and growing worldwide, including in Nepal. This study attempts to understand how domestic CITES policies are translated into action and what effect actions and processes have on compliance. In doing so, this study provides insights into the implementation and enforcement pitfalls of national legislation that explain CITES violations in Nepal. Primarily, we used 26 key informants interviews to learn opinions of experts, and the grounded theory approach for further qualitative data analysis. In addition, we used Najman's (1995) policy implementation analysis framework to explain gaps. Many interrelated variables in the content of the policy, commitment and capacity of the agencies, the roles of clients and coalitions and contextual issues were observed. Variables that emerged suggest pitfalls in the regulatory policy represented by low probability of detection, arrest and punishment. Moreover, redistributive policies in buffer zones of protected areas are needed into perpetuity to benefit locals. Also, conservation organizations' support for building public and political salience is imperative. PMID:22706477

  1. Pitfalls of CITES Implementation in Nepal: A Policy Gap Analysis

    NASA Astrophysics Data System (ADS)

    Dongol, Yogesh; Heinen, Joel T.

    2012-08-01

    Implementation of policy involves multiple agencies operating at multiple levels in facilitating processes and actions to accomplish desired results. The Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) was developed and implemented to regulate and control international wildlife trade, but violations of the agreement are widespread and growing worldwide, including in Nepal. This study attempts to understand how domestic CITES policies are translated into action and what effect actions and processes have on compliance. In doing so, this study provides insights into the implementation and enforcement pitfalls of national legislation that explain CITES violations in Nepal. Primarily, we used 26 key informants interviews to learn opinions of experts, and the grounded theory approach for further qualitative data analysis. In addition, we used Najman's (1995) policy implementation analysis framework to explain gaps. Many interrelated variables in the content of the policy, commitment and capacity of the agencies, the roles of clients and coalitions and contextual issues were observed. Variables that emerged suggest pitfalls in the regulatory policy represented by low probability of detection, arrest and punishment. Moreover, redistributive policies in buffer zones of protected areas are needed into perpetuity to benefit locals. Also, conservation organizations' support for building public and political salience is imperative.

  2. CD-ROM: Potential and Pitfalls.

    ERIC Educational Resources Information Center

    Dreiss, L. Jack; Bashir, Shahzad

    1990-01-01

    Examines issues surrounding CD-ROM as an organizational information management tool: (1) the CD-ROM market; (2) pitfalls, including compatibility, effect on existing information systems, fear of obsolescence, protection of sensitive information, and lack of successful role models; and (3) factors that will fuel growth, including greater…

  3. Pitfalls and Success of Distance Learning.

    ERIC Educational Resources Information Center

    Rendon, Marie Egbert

    This report discusses the pitfalls and success of distance learning programs. The report covers instructional alternatives of telecourse, linked courses, computer-aided learning, correspondence courses, and audio/video instruction. Sixteen concerns for distance learning programs are identified; for example: (1) registration procedures for distance…

  4. Bibliometric analysis of scientific publications in transplantation journals from Mainland China, Japan, South Korea and Taiwan between 2006 and 2015

    PubMed Central

    Lyu, Qiu-Ju; Su, Huai-Yu

    2016-01-01

    Objectives The aim of this study is to compare the quantity and quality of scientific publications in transplantation fields that were written by researchers from Mainland China, Japan, South Korea and Taiwan in the East Asia region. Settings East Asia. Participants and outcome measures Articles except editorials, conference abstracts, letters, news and corrections published in 25 transplantation journals from 2006 to 2015 were screened with the Web of Science database. The number of total and annual articles, article types (study design and transplantation site), impact factor, citations and articles in the high-impact journals was determined to assess the quantity and quality of transplantation research from East Asia. The correlation of socioeconomic factors and annual publications was also analysed. Results From 2006 to 2015, there were 47 141 articles published in transplantation journals, of which researchers from Japan published 3694 articles, followed by Mainland China, South Korea and Taiwan with 2778, 1643 and 951 articles, respectively. Similar trends were observed in accumulated impact factor, accumulated citations, articles in the high-impact journals and articles on transplantation site. Publications from Japan had the highest average impact factor and citation, while those from Mainland China had the lowest. Additionally, in terms of study design, authors from Mainland China contributed to most clinical trials and randomised controlled trials, but authors from Japan contributed to most case reports. The annual numbers of articles from Mainland China and South Korea increased linearly (p<0.05), but those from Japan and Taiwan remained stable for the period studied. The annual numbers of articles from Mainland China and South Korea were positively correlated with gross domestic product (p<0.05). Conclusions Transplantation research productivity in East Asia is highly skewed, with gross domestic product having a significant positive correlation

  5. Publication rates of manuscript presentations at the American College of Foot and Ankle Surgeons Annual Scientific Conference between 1999 and 2008.

    PubMed

    Roukis, Thomas S

    2011-01-01

    Publication is the ultimate desired end point of scientific research. However, oral manuscript presentations of research studies are often referenced in textbooks, journal articles, and industry white papers, and, as a result, influence treatment care plans. No data exist for the actual publication rate of podiatric foot and ankle surgery oral manuscript presentations. Therefore, the objective of this study was to determine the actual publication rates of oral manuscript presentations at the American College of Foot and Ankle Surgeons (ACFAS) Annual Scientific Conference over 10 years. Print or electronic media for the ACFAS Annual Scientific Conference official program between 1999 and 2008 were obtained. Each year's official program was hand searched for any oral manuscript presentation, and, when identified, the title and authors were individually searched through electronic internet-based search engines to determine whether an oral manuscript presentation had been followed by publication of a full-text article. Additionally, pertinent journals were hand searched for potential articles. A total of 67.5% (139/206) oral manuscript presentations were ultimately published in 1 of 12 medical journals in a mean of 14.5 months. All journals except one (91.7%) represented peer-reviewed journals. The publication rate of oral manuscript presentations at the ACFAS Annual Scientific Conference is similar to or greater than orthopaedic subspecialties, including foot and ankle surgery, publication rates. Based on the above, attendees of the ACFAS Annual Scientific Conference should be aware that the majority of oral manuscript material presented at the ACFAS Annual Scientific Conference can be considered as accurate because they survive the rigors of the peer-review process more than two thirds of the time. PMID:21549618

  6. Impact of GDP, Spending on R&D, Number of Universities and Scientific Journals on Research Publications among Asian Countries

    PubMed Central

    Meo, Sultan Ayoub; Al Masri, Abeer A.; Usmani, Adnan Mahmood; Memon, Almas Naeem; Zaidi, Syed Ziauddin

    2013-01-01

    Objectives This study aimed to compare the impact of Gross Domestic Product (GDP) per capita, spending on Research and Development (R&D), number of universities, and Indexed Scientific Journals on total number of research documents (papers), citations per document and Hirsch index (H-index) in various science and social science subjects among Asian countries. Materials and Methods In this study, 40 Asian countries were included. The information regarding Asian countries, their GDP per capita, spending on R&D, total number of universities and indexed scientific journals were collected. We recorded the bibliometric indicators, including total number of research documents, citations per document and H-index in various science and social sciences subjects during the period 1996–2011. The main sources for information were World Bank, SCI-mago/Scopus and Web of Science; Thomson Reuters. Results The mean per capita GDP for all the Asian countries is 14448.31±2854.40 US$, yearly per capita spending on R&D 0.64±0.16 US$, number of universities 72.37±18.32 and mean number of ISI indexed journal per country is 17.97±7.35. The mean of research documents published in various science and social science subjects among all the Asian countries during the period 1996–2011 is 158086.92±69204.09; citations per document 8.67±0.48; and H-index 122.8±19.21. Spending on R&D, number of universities and indexed journals have a positive correlation with number of published documents, citations per document and H-index in various science and social science subjects. However, there was no association between the per capita GDP and research outcomes. Conclusion The Asian countries who spend more on R&D have a large number of universities and scientific indexed journals produced more in research outcomes including total number of research publication, citations per documents and H-index in various science and social science subjects. PMID:23840471

  7. Publication rates of poster presentations at the American College of Foot and Ankle Surgeons annual scientific conference between 1999 and 2008.

    PubMed

    Abicht, Bradley P; Donnenwerth, Michael P; Borkosky, Sara L; Plovanich, Elizabeth J; Roukis, Thomas S

    2012-01-01

    Publication is the desired end point of scientific research. Ultimately, it is desired that research presented in poster format at a scientific conference will be developed into a report and become published in a peer-reviewed scientific journal. Moreover, poster presentations of research studies are often referenced and, as a result, influence treatment care plans. No data exist for the actual publication rate of podiatric foot and ankle surgery poster presentations. Therefore, the objective of the present study was to determine the actual publication rates of poster presentations at the American College of Foot and Ankle Surgeons (ACFAS) annual scientific conference (ASC) during a 10-year period. Print or electronic media for the ACFAS ASC official program from 1999 to 2008 were obtained. Each year's official program was manually searched for any poster presentation and, when identified, the authors and title were individually searched using Internet-based search engines to determine whether a poster presentation had been followed by publication. Of the 825 posters, 198 (24%) poster presentations were ultimately published in 1 of 32 medical journals within a weighted mean of 17.6 months. Of the 32 journals, 25 (78.1%) represented peer-reviewed journals. The publication rate of poster presentations at the ACFAS ASC was less than that of oral manuscripts presented at the same meeting during the same period and was also less than the orthopedic subspecialty poster presentation publication rates. Therefore, attendees of the ACFAS ASC should be aware that only a few of the posters presented at the ACFAS ASC will be valid because they will not survive the rigors of publication 76% of the time. Additionally, more stringent selection criteria should be used so that the selected poster presentations can ultimately withstand the publication process. PMID:22196458

  8. Meaningful public participation in scientific research: How to build an effective site-based long-term education program

    NASA Astrophysics Data System (ADS)

    Barnett, L.

    2013-12-01

    Many site-based educators (Wildlife Refuges, nature centers, Cooperative Extension Programs, schools, arboretums) struggle with developing and implementing cohesive long-term scientific monitoring projects into their existing outreach programming. Moreover, projects that are not meaningful to participants often have little or no sustainable long-term impact. Programs proven most effective are those which 1.) engage the participants in the study design and implementation process, 2.) answer a scientific question posed by site leaders; the data collected supports USA-NPN efforts as well as related site management and monitoring questions, 3.) are built into existing outreach and education programs, using phenology as a lens for understanding both natural and cultural history, and 4.) consistently share outcomes and results with the participants. The USA National Phenology Network's (USA-NPN) Education Program provides phenology curriculum and outreach to educators in formal, non-formal, and informal settings. Materials are designed to serve participants in grades 5-12, higher education, and adult learners. Phenology, used as a lens for place-based education, can inform science, environmental, and climate literacy, as well as other subject areas including cultural studies, art, and language arts. The USA-NPN offers consultation with site leaders on how to successfully engage site-based volunteers and students in long-term phenological studies using Nature's Notebook (NN), the professional and citizen science phenology monitoring program. USA-NPN education and educator instruction materials are designed and field-tested to demonstrate how to implement a long-term NN phenology-monitoring program at such sites. These curricula incorporate monitoring for public visitors, long-term volunteers, and school groups, while meeting the goals of USA-NPN and the site, and can be used as a model for other public participation in science programs interested in achieving similar

  9. Public policy and the social determinants of health: the challenge of the production and use of scientific evidence.

    PubMed

    Pellegrini Filho, Alberto

    2011-01-01

    This article serves as an introduction to the others published in this thematic issue of the Cadernos de Saúde Pública. The author makes a brief historical review of the concepts, approaches and methodologies used to study the relationships between social determinants and health outcomes. By analyzing the current global movement around social determinants of health he emphasizes that the distinctive feature of this movement is the explicit commitment to action through intersectoral public policies that are based on evidence and implemented with the support and participation of broad segments of society. As this special issue of the Cadernos de Saúde Pública is dedicated to presenting the results of research related to social determinants of health, the author focuses on an analysis of the difficulties in the production and use of scientific evidence that supports the definition, implementation and evaluation of policies to combat health inequities through action on social determinants of health. To conclude, he presents some recommendations for overcoming these difficulties. PMID:21789407

  10. Inter-observer agreement on a checklist to evaluate scientific publications in the field of animal reproduction.

    PubMed

    Simoneit, Céline; Heuwieser, Wolfgang; Arlt, Sebastian P

    2012-01-01

    This study's objective was to determine respondents' inter-observer agreement on a detailed checklist to evaluate three exemplars (one case report, one randomized controlled study without blinding, and one blinded, randomized controlled study) of the scientific literature in the field of bovine reproduction. Fourteen international scientists in the field of animal reproduction were provided with the three articles, three copies of the checklist, and a supplementary explanation. Overall, 13 responded to more than 90% of the items. Overall repeatability between respondents using Fleiss's κ was 0.35 (fair agreement). Combining the "strongly agree" and "agree" responses and the "strongly disagree" and "disagree" responses increased κ to 0.49 (moderate agreement). Evaluation of information given in the three articles on housing of the animals (35% identical answers) and preconditions or pretreatments (42%) varied widely. Even though the overall repeatability was fair, repeatability concerning the important categories was high (e.g., level of agreement=98%). Our data show that the checklist is a reasonable and practical supporting tool to assess the quality of publications. Therefore, it may be used in teaching and practicing evidence-based veterinary medicine. It can support training in systematic and critical appraisal of information and in clinical decision making. PMID:22709736

  11. Climate Change and Public Health Policy: Translating the Science

    PubMed Central

    Braks, Marieta; van Ginkel, Rijk; Wint, William; Sedda, Luigi; Sprong, Hein

    2013-01-01

    Public health authorities are required to prepare for future threats and need predictions of the likely impact of climate change on public health risks. They may get overwhelmed by the volume of heterogeneous information in scientific articles and risk relying purely on the public opinion articles which focus mainly on global warming trends, and leave out many other relevant factors. In the current paper, we discuss various scientific approaches investigating climate change and its possible impact on public health and discuss their different roles and functions in unraveling the complexity of the subject. It is not our objective to review the available literature or to make predictions for certain diseases or countries, but rather to evaluate the applicability of scientific research articles on climate change to evidence-based public health decisions. In the context of mosquito borne diseases, we identify common pitfalls to watch out for when assessing scientific research on the impact of climate change on human health. We aim to provide guidance through the plethora of scientific papers and views on the impact of climate change on human health to those new to the subject, as well as to remind public health experts of its multifactorial and multidisciplinary character. PMID:24452252

  12. Climate change and public health policy: translating the science.

    PubMed

    Braks, Marieta; van Ginkel, Rijk; Wint, William; Sedda, Luigi; Sprong, Hein

    2014-01-01

    Public health authorities are required to prepare for future threats and need predictions of the likely impact of climate change on public health risks. They may get overwhelmed by the volume of heterogeneous information in scientific articles and risk relying purely on the public opinion articles which focus mainly on global warming trends, and leave out many other relevant factors. In the current paper, we discuss various scientific approaches investigating climate change and its possible impact on public health and discuss their different roles and functions in unraveling the complexity of the subject. It is not our objective to review the available literature or to make predictions for certain diseases or countries, but rather to evaluate the applicability of scientific research articles on climate change to evidence-based public health decisions. In the context of mosquito borne diseases, we identify common pitfalls to watch out for when assessing scientific research on the impact of climate change on human health. We aim to provide guidance through the plethora of scientific papers and views on the impact of climate change on human health to those new to the subject, as well as to remind public health experts of its multifactorial and multidisciplinary character. PMID:24452252

  13. [Cardiology online: impact and pitfalls of Internet medical news].

    PubMed

    Wood, Shelley M; Topol, Eric J

    2012-01-01

    Twenty years ago, the main sources for physicians seeking information on new procedures, drugs, or devices were meetings and medical journals. The dawn of the Internet radically transformed how news and information is delivered and absorbed, beginning with the launch of online journals back in the mid-1990s. A decade and a half later, physicians can learn about new innovations the moment they are made public, and they can get that news from their phones and tablets, their Twitter or Facebook accounts, or via their favorite blog or medical news web site. Along with the clear advantages of accessing new medical information any time of day comes the need for physicians to be aware of the pitfalls of online medical content and to have a heightened sense of responsibility when it comes to integrating information gleaned online into their medical practices. PMID:22322467

  14. Public debates driven by incomplete scientific data: The cases of evolution theory, global warming and H1N1 pandemic influenza

    NASA Astrophysics Data System (ADS)

    Galam, Serge

    2010-09-01

    Public debates driven by incomplete scientific data where nobody can claim absolute certainty, due to the current state of scientific knowledge, are studied. The cases of evolution theory, global warming and H1N1 pandemic influenza are investigated. The first two are of controversial impact while the third is more neutral and resolved. To adopt a cautious balanced attitude based on clear but inconclusive data appears to be a lose-out strategy. In contrast overstating arguments with incorrect claims which cannot be scientifically refuted appears to be necessary but not sufficient to eventually win a public debate. The underlying key mechanisms of these puzzling and unfortunate conclusions are identified using the Galam sequential probabilistic model of opinion dynamics (Galam, 2002 [4], Galam, 2005 [18], Galam and Jacobs, 2007 [19]). It reveals that the existence of inflexible agents and their respective proportions are the instrumental parameters to determine the faith of incomplete scientific data in public debates. Acting on one’s own inflexible proportion modifies the topology of the flow diagram, which in turn can make irrelevant initial supports. On the contrary focusing on open-minded agents may be useless given some topologies. When the evidence is not as strong as claimed, the inflexibles rather than the data are found to drive the opinion of the population. The results shed a new but disturbing light on designing adequate strategies to win a public debate.

  15. Public Participation in Scientific Research: Defining the Field and Assessing Its Potential for Informal Science Education. A CAISE Inquiry Group Report

    ERIC Educational Resources Information Center

    Bonney, Rick; Ballard, Heidi; Jordan, Rebecca; McCallie, Ellen; Phillips, Tina; Shirk, Jennifer; Wilderman, Candie C.

    2009-01-01

    Despite the growing number of collaborations between volunteers and professional scientists, research efforts investigating the impacts of such collaborations, which we have termed Public Participation in Scientific Research (PPSR), have been very limited. Examples of PPSR projects include citizen science, volunteer monitoring, and participatory…

  16. Pitfalls in diagnosing diabetic foot infections.

    PubMed

    Peters, Edgar J

    2016-01-01

    Although the diagnosis of a diabetic foot infection is made based on clinical symptoms and signs, we also use blood laboratory, microbiological and radiological studies to make treatment decisions. All of these diagnostic studies have pitfalls that can lead to a delay in diagnosis. Such delays will likely lead to further tissue damage and to a higher chance of amputation. One of these pitfalls is that some clinicians rely on microbiological, rather than clinical data, to diagnose infection. Though subjective by nature, clinical signs predict outcome of foot infections accurately. Another pitfall is that microbiological data can be misleading. All wounds harbour microorganisms; therefore, a positive wound culture does not mean that a wound is infected. Furthermore, the outcome of cultures of wound swabs does not correlate well with culture results of tissue biopsies. Therapy guidance by wound swab will likely lead to overtreatment of non-pathogenic organisms. Genotyping might have a role in identifying previously unrecognized (combinations of) pathogens in diabetic foot infection, bacteria in sessile phenotype and non-culturable pathogens, e.g. in cases where antibiotics have already been administered. One more pitfall is that the diagnosis of osteomyelitis remains difficult. Although the result of percutaneous bone biopsy is the reference standard for osteomyelitis, some other diagnostic modalities can aid in the diagnosis. A combination of several of these diagnostic tests is probably a good strategy to achieve a higher diagnostic accuracy. Relying on a single test will likely lead to misidentification of patients with osteomyelitis with associated overtreatment and undertreatment. PMID:26813617

  17. Pitfalls of cholescintigraphy. A case report

    SciTech Connect

    Strickler, S.; Park, H.M.

    1982-12-01

    A /sup 99m/Tc PIPIDA scan was performed in a young auto accident victim who had a transient rise in serum bilirubin level. Initially, the stasis of activity in the right ureter was mistaken for activity in the common bile duct. Misinterpretation of biliary imaging studies can be prevented with awareness of pitfalls and readiness to obtain delayed images and additional images in different projections.

  18. Avoiding common pitfalls when clustering biological data.

    PubMed

    Ronan, Tom; Qi, Zhijie; Naegle, Kristen M

    2016-01-01

    Clustering is an unsupervised learning method, which groups data points based on similarity, and is used to reveal the underlying structure of data. This computational approach is essential to understanding and visualizing the complex data that are acquired in high-throughput multidimensional biological experiments. Clustering enables researchers to make biological inferences for further experiments. Although a powerful technique, inappropriate application can lead biological researchers to waste resources and time in experimental follow-up. We review common pitfalls identified from the published molecular biology literature and present methods to avoid them. Commonly encountered pitfalls relate to the high-dimensional nature of biological data from high-throughput experiments, the failure to consider more than one clustering method for a given problem, and the difficulty in determining whether clustering has produced meaningful results. We present concrete examples of problems and solutions (clustering results) in the form of toy problems and real biological data for these issues. We also discuss ensemble clustering as an easy-to-implement method that enables the exploration of multiple clustering solutions and improves robustness of clustering solutions. Increased awareness of common clustering pitfalls will help researchers avoid overinterpreting or misinterpreting the results and missing valuable insights when clustering biological data. PMID:27303057

  19. Publication rates of abstracts presented at annual scientific meetings: how does the Royal Australian and New Zealand College of Radiologists compare?

    PubMed

    Bydder, Sean A; Joseph, David J; Spry, Nigel A

    2004-03-01

    The abstract to publication ratio (APR) is a measure of the quality of scientific meetings. The aim of the present study was to determine the publication rate of abstracts presented at annual Royal Australian and New Zealand College of Radiologists (RANZCR) conferences, and to identify the publishing journals. All free paper research abstracts (oral or poster) presented by RANZCR radiologists, radiation oncologists and trainees at the four consecutive meetings between 1996 and 1999 were identified retrospectively from conference programmes. The PubMed database (http://www.ncbi.nlm.nih.gov/PubMed/) was searched to determine whether or not the abstract had been published as a full paper. Of the 480 free paper research abstracts, 168 (35%) had been published as full articles. The overall abstract to publication ratio for radiology was 29% and for radiation oncology was 41%. Papers were published in a variety of journals but Australasian Radiology accounted for 27%. The mean time between presentation and publication was 16.5 months (median 17 months). These overall abstract to publication ratios are lower than those reported for overseas-based meetings in each respective area. Guidelines to scientific committees could increase the APR by more rigorous selection of abstracts. Future research should look at barriers to the publication of research findings, and identify ways to assist the publication process. PMID:15027917

  20. Lung cancer cytology: potential pitfalls and mimics - a review

    PubMed Central

    Idowu, Michael O; Powers, Celeste N

    2010-01-01

    Cytology is increasingly being used in the evaluation of lung lesions. There are several potential pitfalls and mimics encountered in the evaluation of respiratory cytology specimens, making interpretation of respiratory cytology challenging. Familiarity with the mimics and the pitfalls is essential in avoiding a misdiagnosis because a false positive or false negative diagnosis may have significant management implications. This article focuses on the main classification of primary lung carcinoma - small cell carcinoma, adenocarcinoma and squamous cell carcinoma - with potential mimics discussed under each tumor category. We have attempted to separate pitfalls from common potential mimics and have suggested general rules when such pitfalls are encountered. PMID:20490328

  1. Archaeology and public perception of a trans-scientific problem; disposal of toxic wastes in the unsaturated zone

    USGS Publications Warehouse

    Winograd, Isaac Judah

    1986-01-01

    Predicting the effects of toxic-waste disposal on the environment over periods of millenia to hundreds of millenia is a transscientific problem; that is, one not fully addressed by quantitative scientific and engineering endeavors. Archaeology is a pertinent adjunct to such predictions in several ways. First, and foremost, archaeological records demonstrate that delicate, as well as durable, objects buried in thick unsaturated zones of arid and semiarid environments may survive intact for millenia to tens of millenia. This successful preservation of Late Paleolithic to Iron Age artifacts provides independent support for the tentative favorable conclusions of earth scientists regarding the general utility of thick unsaturated zones for toxic-waste isolation. By analogy with the archaeological record, solidified toxic wastes of low solubility that are buried in arid unsaturated zones should remain isolated from the environment indefinitely; modern man presumably should be able to improve upon the techniques used by his ancestors to isolate and preserve their sacred and utilitarian objects. Second, archaeological evidence pertinent to the fate of objects buried in unsaturated zones-although qualitative in nature and subject to the limitations of arguments by analogy-is meaningful to the public and to the courts who, with some scientists and engineers, are reluctant to rely exclusively on computer-generated predictions of the effects of buried toxic wastes on the environment. Third, the archaeological record issues a warning that our descendants may intrude into our waste disposal sites and that we must therefore take special measures to minimize such entry and, if it occurs, to warn of the dangers by a variety of symbols. And fourth, archaeology provides a record of durable natural and manmade materials that may prove to be suitable for encapsulation of our wastes and from which we can construct warning markers that will last for millenia. For these four reasons

  2. Mainstream Issues of Education and Public Awareness of Space Activities and Sciences among universities and Scientific Institutes.

    NASA Astrophysics Data System (ADS)

    Singh, Balbir

    This paper is an effort to study and analyze several constraints and issues of space technology and education that organizations other than governmental organizations face in awareness program. In recent years, advancements in technologies have made it possible for Volunteer and Technical Communities, non-government organizations, private agencies and academic research institutions to provide increasing support to space education management and emphasis on response efforts. Important cornerstones of this effort and support are the possibility to access and take advantage of satellite imagery as well as the use of other space-based technologies such as telecommunications satellites and global navigation satellite systems included in main curriculum plus the implementation of programs for use of high class sophisticated technologies used by industries to the students and researchers of non-space faring nations. The authors recognize the importance of such new methodologies for education and public Awareness. This paper demonstrates many hurdles universities and scientific institutions face including lack of access in terms of financial and technical resources for better support. A new model for coordinated private sector partnership in response to space sciences and education has been discussed. In depth analysis and techniques need to connect these pioneering communities with the space industry as well as the space governmental agencies, with special emphasis on financial constraints. The paper mandates its role to promote the use of space-based information; its established networks bringing together national institutions responsible for these space based activities, as well as other end users, and space solution experts; and its technical foundation, particularly in the area of information technologies. To help building a tighter cooperation and further understanding among all these communities, paper delivers an intensive report and solutions for future

  3. A Comparative Study of Scientific Publications in Health Care Sciences and Services from Mainland China, Taiwan, Japan, and India (2007–2014)

    PubMed Central

    Lv, Yipeng; Tang, Bihan; Liu, Xu; Xue, Chen; Liu, Yuan; Kang, Peng; Zhang, Lulu

    2015-01-01

    In this study, we aimed to compare the quantity and quality of publications in health care sciences and services journals from the Chinese mainland, Taiwan, Japan, and India. Journals in this category of the Science Citation Index Expanded were included in the study. Scientific papers were retrieved from the Web of Science online database. Quality was measured according to impact factor, citation of articles, number of articles published in top 10 journals, and the 10 most popular journals by country (area). In the field of health care sciences and services, the annual incremental rates of scientific articles published from 2007 to 2014 were higher than rates of published scientific articles in all fields. Researchers from the Chinese mainland published the most original articles and reviews and had the highest accumulated impact factors, highest total article citations, and highest average citation. Publications from India had the highest average impact factor. In the field of health care sciences and services, China has made remarkable progress during the past eight years in the annual number and percentage of scientific publications. Yet, there is room for improvement in the quantity and quality of such articles. PMID:26712774

  4. [Scientific presentation].

    PubMed

    Kraft, Giuliano

    2002-01-01

    To give a correct and effective scientific presentation, is an arduous task that asks for close examination of basic techniques of communication. This article proposes indications and suggestions to help public speakers to be communicators, to use visual aids and it explains how to capture the audience attention. PMID:12599721

  5. Lifecycle analysis: Uses and pitfalls

    SciTech Connect

    Gaines, L.; Stodolsky, F.

    1997-04-01

    Lifecycle analysis (LCA) is a powerful tool, often used as an aid to decision making in industry and for public policy. LCA forms the foundation of the newly-invented field of industrial ecology. There are several possible uses and users for this tool. It can be used to evaluate the impacts from a process or from production and use of a product. Impacts from competing products or processes can be compared to help manufacturers or consumers choose among options, including foregoing the service the product or process would have provided because the impacts are too great. Information about impacts can be used by governments to set regulations, taxes, or tariffs; to allocate funds for research and development (R&D) or low-interest loans; or to identify projects worthy to receive tax credits. In addition, LCA can identify key process steps and, most important, key areas where process changes, perhaps enabled by R&D, could significantly reduce impacts. Analysts can use the results to help characterize the ramifications of possible policy options or technological changes.

  6. Toward an Understanding of the Environmental and Public Health Impacts of Unconventional Natural Gas Development: A Categorical Assessment of the Peer-Reviewed Scientific Literature, 2009-2015

    PubMed Central

    Hays, Jake; Shonkoff, Seth B. C.

    2016-01-01

    The body of science evaluating the potential impacts of unconventional natural gas development (UNGD) has grown significantly in recent years, although many data gaps remain. Still, a broad empirical understanding of the impacts is beginning to emerge amidst a swell of research. The present categorical assessment provides an overview of the peer-reviewed scientific literature from 2009–2015 as it relates to the potential impacts of UNGD on public health, water quality, and air quality. We have categorized all available original research during this time period in an attempt to understand the weight and direction of the scientific literature. Our results indicate that at least 685 papers have been published in peer-reviewed scientific journals that are relevant to assessing the impacts of UNGD. 84% of public health studies contain findings that indicate public health hazards, elevated risks, or adverse health outcomes; 69% of water quality studies contain findings that indicate potential, positive association, or actual incidence of water contamination; and 87% of air quality studies contain findings that indicate elevated air pollutant emissions and/or atmospheric concentrations. This paper demonstrates that the weight of the findings in the scientific literature indicates hazards and elevated risks to human health as well as possible adverse health outcomes associated with UNGD. There are limitations to this type of assessment and it is only intended to provide a snapshot of the scientific knowledge based on the available literature. However, this work can be used to identify themes that lie in or across studies, to prioritize future research, and to provide an empirical foundation for policy decisions. PMID:27096432

  7. Toward an Understanding of the Environmental and Public Health Impacts of Unconventional Natural Gas Development: A Categorical Assessment of the Peer-Reviewed Scientific Literature, 2009-2015.

    PubMed

    Hays, Jake; Shonkoff, Seth B C

    2016-01-01

    The body of science evaluating the potential impacts of unconventional natural gas development (UNGD) has grown significantly in recent years, although many data gaps remain. Still, a broad empirical understanding of the impacts is beginning to emerge amidst a swell of research. The present categorical assessment provides an overview of the peer-reviewed scientific literature from 2009-2015 as it relates to the potential impacts of UNGD on public health, water quality, and air quality. We have categorized all available original research during this time period in an attempt to understand the weight and direction of the scientific literature. Our results indicate that at least 685 papers have been published in peer-reviewed scientific journals that are relevant to assessing the impacts of UNGD. 84% of public health studies contain findings that indicate public health hazards, elevated risks, or adverse health outcomes; 69% of water quality studies contain findings that indicate potential, positive association, or actual incidence of water contamination; and 87% of air quality studies contain findings that indicate elevated air pollutant emissions and/or atmospheric concentrations. This paper demonstrates that the weight of the findings in the scientific literature indicates hazards and elevated risks to human health as well as possible adverse health outcomes associated with UNGD. There are limitations to this type of assessment and it is only intended to provide a snapshot of the scientific knowledge based on the available literature. However, this work can be used to identify themes that lie in or across studies, to prioritize future research, and to provide an empirical foundation for policy decisions. PMID:27096432

  8. Pitfalls of Personal Development Plans--The User Perspective

    ERIC Educational Resources Information Center

    Grohnert, Therese; Beausaert, Simon; Segers, Mien

    2014-01-01

    This study was conducted to investigate which pitfalls users of personal development plans (PDPs) perceive in business and governmental organisations with mandatory PDP use. Hundred and thirty-one written statements of PDP users across three Dutch organisations were analysed and categorised into nine pitfalls. Next to an overall lack of use and…

  9. Bioinformatics in proteomics: application, terminology, and pitfalls.

    PubMed

    Wiemer, Jan C; Prokudin, Alexander

    2004-01-01

    Bioinformatics applies data mining, i.e., modern computer-based statistics, to biomedical data. It leverages on machine learning approaches, such as artificial neural networks, decision trees and clustering algorithms, and is ideally suited for handling huge data amounts. In this article, we review the analysis of mass spectrometry data in proteomics, starting with common pre-processing steps and using single decision trees and decision tree ensembles for classification. Special emphasis is put on the pitfall of overfitting, i.e., of generating too complex single decision trees. Finally, we discuss the pros and cons of the two different decision tree usages. PMID:15237926

  10. Pitfalls in colour photography of choroidal tumours

    PubMed Central

    Schalenbourg, A; Zografos, L

    2013-01-01

    Colour imaging of fundus tumours has been transformed by the development of digital and confocal scanning laser photography. These advances provide numerous benefits, such as panoramic images, increased contrast, non-contact wide-angle imaging, non-mydriatic photography, and simultaneous angiography. False tumour colour representation can, however, cause serious diagnostic errors. Large choroidal tumours can be totally invisible on angiography. Pseudogrowth can occur because of artefacts caused by different methods of fundus illumination, movement of reference blood vessels, and flattening of Bruch's membrane and sclera when tumour regression occurs. Awareness of these pitfalls should prevent the clinician from misdiagnosing tumours and wrongfully concluding that a tumour has grown. PMID:23238442

  11. Can artificial parthenogenesis sidestep ethical pitfalls in human therapeutic cloning? An historical perspective.

    PubMed

    Fangerau, H

    2005-12-01

    The aim of regenerative medicine is to reconstruct tissue that has been lost or pathologically altered. Therapeutic cloning seems to offer a method of achieving this aim; however, the ethical debate surrounding human therapeutic cloning is highly controversial. Artificial parthenogenesis-obtaining embryos from unfertilised eggs-seems to offer a way to sidestep these ethical pitfalls. Jacques Loeb (1859-1924), the founding father of artificial parthenogenesis, faced negative public opinion when he published his research in 1899. His research, the public's response to his findings, and his ethical foundations serve as an historical argument both for the communication of science and compromise in biological research. PMID:16319240

  12. Can artificial parthenogenesis sidestep ethical pitfalls in human therapeutic cloning? An historical perspective

    PubMed Central

    Fangerau, H

    2005-01-01

    The aim of regenerative medicine is to reconstruct tissue that has been lost or pathologically altered. Therapeutic cloning seems to offer a method of achieving this aim; however, the ethical debate surrounding human therapeutic cloning is highly controversial. Artificial parthenogenesis—obtaining embryos from unfertilised eggs—seems to offer a way to sidestep these ethical pitfalls. Jacques Loeb (1859–1924), the founding father of artificial parthogenesis, faced negative public opinion when he published his research in 1899. His research, the public's response to his findings, and his ethical foundations serve as an historical argument both for the communication of science and compromise in biological research. PMID:16319240

  13. Investigation of the Public Library as a Linking Agent to Major Scientific, Educational, Social and Environmental Data Bases. Two-Year Interim Report. Annex 2: Publicity Aspects.

    ERIC Educational Resources Information Center

    Summit, Roger K.; Firschein, Oscar

    Project Dialib was a two-year investigation of the impact of on line information retrieval in a public library setting. This volume documents the efforts that were made to publicize the project and to promote the use of the service among library patrons. (JY)

  14. Increasing Public Access to Scientific Research through Stakeholder Involvement: Ecological Effects of Sea Level Rise in the Northern Gulf of Mexico

    NASA Astrophysics Data System (ADS)

    Hagen, S. C.; Stephens, S. H.; DeLorme, D. E.; Ruple, D.; Graham, L.

    2013-12-01

    Sea level rise (SLR) has the potential to have a myriad of deleterious effects on coastal ecology and human infrastructure. Stakeholders, including managers of coastal resources, must be aware of potential consequences of SLR and adjust their plans accordingly to protect and preserve the resources under their care. Members of the public, particularly those who live or work in coastal areas, should also be informed about the results of scientific research on the effects of SLR. However, research results are frequently published in venues or formats to which resource managers and the broader public have limited access. It is imperative for scientists to move beyond traditional publication venues in order to more effectively disseminate the results of their research (Dennison, W. 2007, Estu. Coast. Shelf Sci. 77, 185). One potentially effective way to advance public access to research is to incorporate stakeholder involvement into the research project process in order to target study objectives and tailor communication products toward stakeholder needs (Lemos, M. & Morehouse, B. 2005, Glob. Env. Chg. 15, 57). However, it is important to manage communication and clarify participant expectations during this type of research (Gawith, M. et al. 2009, Glob. Env. Chg. 19, 113). This presentation describes the process being undertaken by an ongoing 5-year multi-disciplinary NOAA-funded project, Ecological Effects of Sea Level Rise in the Northern Gulf of Mexico (EESLR-NGOM), to improve accessibility and utility of scientific research results through stakeholder engagement. The EESLR-NGOM project is assessing the ecological risks from SLR along the Mississippi, Alabama and Florida Panhandle coasts, coastal habitats, and floodplains. It has incorporated stakeholder involvement throughout the research process so as to better target and tailor the emerging research products to meet resource managers' needs, as well as to facilitate eventual public dissemination of results. An

  15. 76 FR 4109 - Science Advisory Board Staff Office; Notification of a Public Meeting of the Clean Air Scientific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-24

    ... Ambient Air Quality Standards for NOX and SOX: First External Review Draft (March 2010) (75 FR 10479... in 75 FR 54871-54872, on October 6-7, 2010, the CASAC Panel met to review EPA's Policy Assessment for..., of the Clean Air Scientific Advisory Committee (CASAC) Oxides of Nitrogen (NO X ) and Sulfur...

  16. Public engagement with scientific evidence in health: A qualitative study among primary-care patients in an urban population.

    PubMed

    Schapira, Marilyn M; Imbert, Diana; Oh, Eric; Byhoff, Elena; Shea, Judy A

    2016-07-01

    The purpose of this study is to explore the experience and perspective of patients regarding scientific evidence in health and the degree that this information impacts health behavior and medical decision making. A focus group study was conducted. Participants were recruited from an urban primary-care practice. The focus group discussions were audio-recorded, transcribed verbatim, and coded by two independent investigators. Emergent themes were identified. Participants (n = 30) ranged in age from 30 to 79 years, 60% were female, 77% were black, and 50% had at least some college experience. Three thematic areas informed a wide range in level of interest regarding scientific study design and result information: (1) scientific literacy, (2) medical decision making style, and (3) impact of culture and community on decision making. Our findings indicate that communication strategies that incorporate key elements of scientific study design, methods, and results will most effectively translate findings from comparative effectiveness research to patient-informed decision making regarding evidence-based health interventions. PMID:25491359

  17. What is Authorship, and What Should it Be? A Survey of Prominent Guidelines for Determining Authorship in Scientific Publications

    ERIC Educational Resources Information Center

    Osborne, Jason W.; Holland, Abigail

    2009-01-01

    Before the mid 20th century most scientific writing was solely authored (Claxton, 2005; Greene, 2007) and thus it is only relatively recently, as science has grown more complex, that the ethical and procedural issues around authorship have arisen. Fields as diverse as medicine (International Committee of Medical Journal Editors, 2008), mathematics…

  18. Academic Entrepreneurship in France: The Promotion of Economic Returns of Public Research and Its Political and Scientific Challenges

    ERIC Educational Resources Information Center

    Manifet, Christelle

    2008-01-01

    Emphasising the level of the observation of university configurations and the example of academic entrepreneurship, the author analyses the drivers of economic returns of public research in France. Based on the study of national public policy in this field since 1999 and a general survey of the paths of researchers-entrepreneurs, the article…

  19. Publications

    Cancer.gov

    Information about NCI publications including PDQ cancer information for patients and health professionals, patient-education publications, fact sheets, dictionaries, NCI blogs and newsletters and major reports.

  20. Experimental phasing: best practice and pitfalls

    PubMed Central

    McCoy, Airlie J.; Read, Randy J.

    2010-01-01

    Developments in protein crystal structure determination by experimental phasing are reviewed, emphasizing the theoretical continuum between experimental phasing, density modification, model building and refinement. Traditional notions of the composition of the substructure and the best coefficients for map generation are discussed. Pitfalls such as determining the enantiomorph, identifying centrosymmetry (or pseudo-symmetry) in the substructure and crystal twinning are discussed in detail. An appendix introduces com­bined real–imaginary log-likelihood gradient map coefficients for SAD phasing and their use for substructure completion as implemented in the software Phaser. Supplementary material includes animated probabilistic Harker diagrams showing how maximum-likelihood-based phasing methods can be used to refine parameters in the case of SIR and MIR; it is hoped that these will be useful for those teaching best practice in experimental phasing methods. PMID:20382999

  1. Potential Pitfalls in microRNA Profiling

    PubMed Central

    Chugh, Pauline; Dittmer, Dirk P.

    2013-01-01

    MicroRNAs (miRNAs) are small, noncoding RNAs that post-transcriptionally influence a wide range of cellular processes such as the host response to viral infection, innate immunity, cell cycle progression, migration and apoptosis through the inhibition of target mRNA translation. Due to the growing number of microRNAs and identification of their functional roles, miRNA profiling of many different sample types has become more expansive, especially with relevance to disease signatures. Here, we address some of the advantages and potential pitfalls of the currently available methods for miRNA expression profiling. Some of the topics discussed include isomiRNAs, comparison of different profiling platforms, normalization strategies and issues with regard to sample preparation and experimental analyses. PMID:22566380

  2. Microstructure Informed Tractography: Pitfalls and Open Challenges

    PubMed Central

    Daducci, Alessandro; Dal Palú, Alessandro; Descoteaux, Maxime; Thiran, Jean-Philippe

    2016-01-01

    One of the major limitations of diffusion MRI tractography is that the fiber tracts recovered by existing algorithms are not truly quantitative. Local techniques for estimating more quantitative features of the tissue microstructure exist, but their combination with tractography has always been considered intractable. Recent advances in local and global modeling made it possible to fill this gap and a number of promising techniques for microstructure informed tractography have been suggested, opening new and exciting perspectives for the quantification of brain connectivity. The ease-of-use of the proposed solutions made it very attractive for researchers to include such advanced methods in their analyses; however, this apparent simplicity should not hide some critical open questions raised by the complexity of these very high-dimensional problems, otherwise some fundamental issues may be pushed into the background. The aim of this article is to raise awareness in the diffusion MRI community, notably researchers working on brain connectivity, about some potential pitfalls and modeling choices that make the interpretation of the outcomes from these novel techniques rather cumbersome. Through a series of experiments on synthetic and real data, we illustrate practical situations where erroneous and severely biased conclusions may be drawn about the connectivity if these pitfalls are overlooked, like the presence of partial/missing/duplicate fibers or the critical importance of the diffusion model adopted. Microstructure informed tractography is a young but very promising technology, and by acknowledging its current limitations as done in this paper, we hope our observations will trigger further research in this direction and new ideas for truly quantitative and biologically meaningful analyses of the connectivity. PMID:27375412

  3. Microstructure Informed Tractography: Pitfalls and Open Challenges.

    PubMed

    Daducci, Alessandro; Dal Palú, Alessandro; Descoteaux, Maxime; Thiran, Jean-Philippe

    2016-01-01

    One of the major limitations of diffusion MRI tractography is that the fiber tracts recovered by existing algorithms are not truly quantitative. Local techniques for estimating more quantitative features of the tissue microstructure exist, but their combination with tractography has always been considered intractable. Recent advances in local and global modeling made it possible to fill this gap and a number of promising techniques for microstructure informed tractography have been suggested, opening new and exciting perspectives for the quantification of brain connectivity. The ease-of-use of the proposed solutions made it very attractive for researchers to include such advanced methods in their analyses; however, this apparent simplicity should not hide some critical open questions raised by the complexity of these very high-dimensional problems, otherwise some fundamental issues may be pushed into the background. The aim of this article is to raise awareness in the diffusion MRI community, notably researchers working on brain connectivity, about some potential pitfalls and modeling choices that make the interpretation of the outcomes from these novel techniques rather cumbersome. Through a series of experiments on synthetic and real data, we illustrate practical situations where erroneous and severely biased conclusions may be drawn about the connectivity if these pitfalls are overlooked, like the presence of partial/missing/duplicate fibers or the critical importance of the diffusion model adopted. Microstructure informed tractography is a young but very promising technology, and by acknowledging its current limitations as done in this paper, we hope our observations will trigger further research in this direction and new ideas for truly quantitative and biologically meaningful analyses of the connectivity. PMID:27375412

  4. Pitfalls of mechanical ventilation in Thailand.

    PubMed

    Bunburaphong, Thananchai

    2014-01-01

    Pitfalls in the respiratory care and mechanical ventilation for patients continue to prevail in intensive care unit (ICU) or in some hospital wards in Thailand. There are two reasons that explain this phenomenon. Firstly, there are no professional respiratory therapists in Thailand. Secondly, most caregivers do not possess the adequate knowledge and skills requiredfor respiratory care and for initiating, maintaining and weaning patients off mechanical ventilation. Physicians and nurses have to practice in respiratory care and mechanical ventilation without participating in adequate training during their undergraduate studies and postgraduate training. In reality, physicians pay almost no attention to respiratory care. They leave the respiratory toilet, ventilator changes and monitoring of the patients to nurses who have many other tasks to attend to. To solve this problem will require restructuring of the Thai healthcare system. The Parliament will need to pass a "Respiratory Therapy Profession Act" to certify "respiratory therapists " as a new, registered health profession. The Office of the Civil Service Commission has to take the responsibility for creating the job title and a job description for respiratory therapists. Academic institutes have to provide training courses in respiratory therapy and grant appropriate levels of diplomas or certificates in respiratory therapy. Did actics and clinical skills required for respiratory care have to be sufficiently integrated into the curricula for medical students as well as nursing students. Physicians and nurses need to master their skills and acquired appropriate knowledge in respiratory care and mechanical ventilation until we can assure the necessary number of registered or certified respiratory therapists here in Thailand to help avoid such pitfalls. PMID:24855857

  5. "Everybody knows psychology is not a real science": Public perceptions of psychology and how we can improve our relationship with policymakers, the scientific community, and the general public.

    PubMed

    Ferguson, Christopher J

    2015-09-01

    In a recent seminal article, Lilienfeld (2012) argued that psychological science is experiencing a public perception problem that has been caused by both public misconceptions about psychology, as well as the psychological science community's failure to distinguish itself from pop psychology and questionable therapeutic practices. Lilienfeld's analysis is an important and cogent synopsis of external problems that have limited psychological science's penetration into public knowledge. The current article expands upon this by examining internal problems, or problems within psychological science that have potentially limited its impact with policymakers, other scientists, and the public. These problems range from the replication crisis and defensive reactions to it, overuse of politicized policy statements by professional advocacy groups such as the American Psychological Association (APA), and continued overreliance on mechanistic models of human behavior. It is concluded that considerable problems arise from psychological science's tendency to overcommunicate mechanistic concepts based on weak and often unreplicated (or unreplicable) data that do not resonate with the everyday experiences of the general public or the rigor of other scholarly fields. It is argued that a way forward can be seen by, on one hand, improving the rigor and transparency of psychological science, and making theoretical innovations that better acknowledge the complexities of the human experience. (PsycINFO Database Record PMID:26348335

  6. The Pleasures and the Pitfalls of Plant Science Activities.

    ERIC Educational Resources Information Center

    Hershey, David R.

    2000-01-01

    Classroom plant activities have long been inexpensive, easy to do, and fun for students, and have become more central to biology teaching. Introduces some plant science activities and their pleasures and pitfalls. (ASK)

  7. Pitfalls in Using Electrophysiological Studies to Diagnose Neuromuscular Disorders

    PubMed Central

    Koo, Yong Seo; Cho, Charles S.

    2012-01-01

    Electrodiagnostic testing is used widely for the full characterization of neuromuscular disorders and for providing unique information on the processes underlying the pathology of peripheral nerves and muscles. However, such testing should be considered as an extension of anamnesis and physical examination, not as pathognomonic of a specific disease entity. There are many pitfalls that could lead to erroneous interpretation of electrophysiological study results when the studies are not performed properly or if they are performed in the presence of anatomical aberrations. The diagnostic reliability of electrodiagnostic studies can be improved and the associated pitfalls overcome if the physician is familiar with all of those possible pitfalls. In this article we discuss the most common and important pitfalls associated with electrodiagnostic medicine. PMID:22523508

  8. Scientific publications in critical care medicine journals from East Asia: A 10-year survey of the literature

    PubMed Central

    Cao, Zhenyu; Ou, Chongyang; Teng, Hongfei; Liu, Xiguang; Tang, Hongxin

    2016-01-01

    Objective: The quantity and quality of publications in critical care medicine from East Asia haven’t been reported. This study aimed to investigate the contribution of publications from East Asia. Methods: Articles from China, Japan and South Korea in 2005 to 2014 were retrieved from Web of Science and Pubmed. The number of publications, impact factor, citation, and article types were analyzed. Results: There were 3076 publications from East Asia (1720 from China, 913 from Japan, and 443 from South Korea). There were a significant decrease in publications from Japan (p = 0.024) and significant increases from China (p = 0.000) and South Korea (p = 0.009). From 2006, the number of articles from China exceed Japan. China had the highest total impact factor (6618.48) and citation (18416), followed by Japan (4566.03; 15440) and South Korea (1998.19; 5599). Japan had the highest mean impact factor (5.00) and citations (16.91), followed by South Korea (4.51; 12.64) and China (3.85; 10.71). Conclusions: China and South Korea`s contributions to critical care medicine had significant increases during the past 10 years, while Japan had a significant decrease. China was the most productive region in East Asia since 2006. Japan had the highest quality research output. PMID:27182223

  9. The evolution of peer review as a basis for scientific publication: directional selection towards a robust discipline?

    PubMed

    Ferreira, Catarina; Bastille-Rousseau, Guillaume; Bennett, Amanda M; Ellington, E Hance; Terwissen, Christine; Austin, Cayla; Borlestean, Adrian; Boudreau, Melanie R; Chan, Kevin; Forsythe, Adrian; Hossie, Thomas J; Landolt, Kristen; Longhi, Jessica; Otis, Josée-Anne; Peers, Michael J L; Rae, Jason; Seguin, Jacob; Watt, Cristen; Wehtje, Morgan; Murray, Dennis L

    2016-08-01

    Peer review is pivotal to science and academia, as it represents a widely accepted strategy for ensuring quality control in scientific research. Yet, the peer-review system is poorly adapted to recent changes in the discipline and current societal needs. We provide historical context for the cultural lag that governs peer review that has eventually led to the system's current structural weaknesses (voluntary review, unstandardized review criteria, decentralized process). We argue that some current attempts to upgrade or otherwise modify the peer-review system are merely sticking-plaster solutions to these fundamental flaws, and therefore are unlikely to resolve them in the long term. We claim that for peer review to be relevant, effective, and contemporary with today's publishing demands across scientific disciplines, its main components need to be redesigned. We propose directional changes that are likely to improve the quality, rigour, and timeliness of peer review, and thereby ensure that this critical process serves the community it was created for. PMID:25865035

  10. Museum Exhibition on Testing and Measurement: Scientific Principles, Social Impact of Testing, and Dialogue with the Public

    ERIC Educational Resources Information Center

    Allalouf, Avi; Alderoqui-Pinus, Diana

    2012-01-01

    This article deals with a pioneering project currently being developed, namely, the Exhibition on Testing and Measurement. This interactive traveling exhibition will be presented in science museums in Israel, the United States, and other countries. It has been conceived as an innovative means of familiarizing the public with educational…

  11. 76 FR 36120 - Science Advisory Board Staff Office Notification of a Public Meeting of the Clean Air Scientific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-21

    ... Review Draft) in a teleconference on May 5, 2011 (76 FR 21346-21347) as reported in a letter to the EPA... Review Panel to conduct a peer review of EPA's Integrated Science Assessment for Lead (First External... given that the CASAC Lead Review Panel will hold a public meeting to peer review EPA's...

  12. 75 FR 32763 - Science Advisory Board Staff Office; Notification of a Public Meeting of the Clean Air Scientific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ... FR 10527-10528). The Panel previously held a public teleconference on November 30, 2007 (announced November 8, 2007 in 72 FR 63177-63178) to provide consultative advice on EPA's Draft Integrated Review Plan..., 2009 meeting was announced February 19, 2009 in 74 FR 7688-7689. As announced September 10, 2009 in...

  13. Publications.

    ERIC Educational Resources Information Center

    Aviation/Space, 1980

    1980-01-01

    Presents a variety of publications available from government and nongovernment sources. The government publications are from the Federal Aviation Administration (FAA) and the National Aeronautics and Space Administration (NASA) and are designed for educators, students, and the public. (Author/SA)

  14. The Impact of Community Design and Land-Use Choices on Public Health: A Scientific Research Agenda

    PubMed Central

    Dannenberg, Andrew L.; Jackson, Richard J.; Frumkin, Howard; Schieber, Richard A.; Pratt, Michael; Kochtitzky, Chris; Tilson, Hugh H.

    2003-01-01

    The design of a community’s built environment influences the physical and mental health of its residents. Because few studies have investigated this relationship, the Centers for Disease Control and Prevention hosted a workshop in May 2002 to help develop a scientific research agenda on these issues. Workshop participants’ areas of expertise included physical activity, injury prevention, air pollution, water quality, urban planning, transportation, architecture, epidemiology, land use, mental health, social capital, housing, and social marketing. This report describes the 37 questions in the resulting research agenda. The next steps are to define priorities and obtain resources. The proposed research will help identify the best practices for designing new communities and revitalizing old ones in ways that promote physical and mental health. PMID:12948970

  15. [Medline criteria for scientific journals selection. Methodology and indicators. Application to Spanish medical journals paying special attention to public health].

    PubMed

    Delgado López-Cózar, Emilio; Ruiz-Pérez, Rafael; Jiménez-Contreras, Evaristo

    2006-01-01

    Due to the strict selection process applied to its indexed journals, Medline is the most prestigious database in the Health and medicine field. The aim of this paper is both to analyze its selection criteria and translate into indicators that can be applied to Spanish medical journals willing to enter the Index Medicus. Analysis samples and methodology to apply obtained from the five groups of criteria considered by Medline (namely, Scope and coverage, Quality of contents, Quality of editorial work, Production quality and Audience) are proposed. A list of qualitative and quantitative indicators related to the five groups of criteria used by Medline is presented; namely, journal scientific output in the national and international context of the discipline, citation, analysis of the editorial committees, the editorial process and the peer-review system, indicators on compliance with the Vancouver guidelines, journal layout and informational quality, attractiveness, audience, journal visibility and interest as regards Medline goals. PMID:17193815

  16. Toward the Assessment of Scientific and Public Health Impacts of the National Institute of Environmental Health Sciences Extramural Asthma Research Program Using Available Data

    PubMed Central

    Liebow, Edward; Phelps, Jerry; Van Houten, Bennett; Rose, Shyanika; Orians, Carlyn; Cohen, Jennifer; Monroe, Philip; Drew, Christina H.

    2009-01-01

    Background In the past 15 years, asthma prevalence has increased and is disproportionately distributed among children, minorities, and low-income persons. The National Institute of Environmental Health Sciences (NIEHS) Division of Extramural Research and Training developed a framework to measure the scientific and health impacts of its extramural asthma research to improve the scientific basis for reducing the health effects of asthma. Objectives Here we apply the framework to characterize the NIEHS asthma portfolio’s impact in terms of publications, clinical applications of findings, community interventions, and technology developments. Methods A logic model was tailored to inputs, outputs, and outcomes of the NIEHS asthma portfolio. Data from existing National Institutes of Health (NIH) databases are used, along with publicly available bibliometric data and structured elicitation of expert judgment. Results NIEHS is the third largest source of asthma-related research grant funding within the NIH between 1975 and 2005, after the National Heart, Lung, and Blood Institute and the National Institute of Allergy and Infectious Diseases. Much of NIEHS-funded asthma research focuses on basic research, but results are often published in journals focused on clinical investigation, increasing the likelihood that the work is moved into practice along the “bench to bedside” continuum. NIEHS support has led to key breakthroughs in scientific research concerning susceptibility to asthma, environmental conditions that heighten asthma symptoms, and cellular mechanisms that may be involved in treating asthma. Conclusions If gaps and limitations in publicly available data receive adequate attention, further linkages can be demonstrated between research activities and public health improvements. This logic model approach to research impact assessment demonstrates that it is possible to conceptualize program components, mine existing databases, and begin to show longer

  17. Scientific and public responses to the ongoing volcanic crisis at Popocatépetl Volcano, Mexico: Importance of an effective hazards-warning system

    NASA Astrophysics Data System (ADS)

    De la Cruz-Reyna, Servando; Tilling, Robert I.

    2008-02-01

    Volcanic eruptions and other potentially hazardous natural phenomena occur independently of any human actions. However, such phenomena can cause disasters when a society fails to foresee the hazardous manifestations and adopt adequate measures to reduce its vulnerability. One of the causes of such a failure is the lack of a consistent perception of the changing hazards posed by an ongoing eruption, i.e., with members of the scientific community, the Civil Protection authorities and the general public having diverging notions about what is occurring and what may happen. The problem of attaining a perception of risk as uniform as possible in a population measured in millions during an evolving eruption requires searching for communication tools that can describe—as simply as possible—the relations between the level of threat posed by the volcano, and the level of response of the authorities and the public. The hazards-warning system adopted at Popocatépetl Volcano, called the Volcanic Traffic Light Alert System (VTLAS), is a basic communications protocol that translates volcano threat into seven levels of preparedness for the emergency-management authorities, but only three levels of alert for the public (color coded green-yellow-red). The changing status of the volcano threat is represented as the most likely scenarios according to the opinions of an official scientific committee analyzing all available data. The implementation of the VTLAS was intended to reduce the possibility of ambiguous interpretations of intermediate levels by the endangered population. Although the VTLAS is imperfect and has not solved all problems involved in mass communication and decision-making during a volcanic crisis, it marks a significant advance in the management of volcanic crises in Mexico.

  18. Scientific and public responses to the ongoing volcanic crisis at Popocatépetl Volcano, Mexico: Importance of an effective hazards-warning system

    USGS Publications Warehouse

    de la Cruz-Reyna, Servando; Tilling, Robert I.

    2008-01-01

    Volcanic eruptions and other potentially hazardous natural phenomena occur independently of any human actions. However, such phenomena can cause disasters when a society fails to foresee the hazardous manifestations and adopt adequate measures to reduce its vulnerability. One of the causes of such a failure is the lack of a consistent perception of the changing hazards posed by an ongoing eruption, i.e., with members of the scientific community, the Civil Protection authorities and the general public having diverging notions about what is occurring and what may happen. The problem of attaining a perception of risk as uniform as possible in a population measured in millions during an evolving eruption requires searching for communication tools that can describe—as simply as possible—the relations between the level of threat posed by the volcano, and the level of response of the authorities and the public. The hazards-warning system adopted at Popocatépetl Volcano, called the Volcanic Traffic Light Alert System(VTLAS), is a basic communications protocol that translates volcano threat into seven levels of preparedness for the emergency-management authorities, but only three levels of alert for the public (color coded green–yellow–red). The changing status of the volcano threat is represented as the most likely scenarios according to the opinions of an official scientific committee analyzing all available data. The implementation of the VTLAS was intended to reduce the possibility of ambiguous interpretations of intermediate levels by the endangered population. Although the VTLAS is imperfect and has not solved all problems involved in mass communication and decision-making during a volcanic crisis, it marks a significant advance in the management of volcanic crises in Mexico.

  19. Open Access Centre at the Nature Research Centre: a facility for enhancement of scientific research, education and public outreach in Lithuania

    NASA Astrophysics Data System (ADS)

    Šerpenskienė, Silvija; Skridlaitė, Gražina

    2014-05-01

    Open Access Centre (OAC) was established in Vilnius, Lithuania in 2013 as a subdivision of the Nature Research Centre (NRC) operating on the principle of open access for both internal and external users. The OAC consists of 15 units, i.e. 15 NRC laboratories or their branches. Forty four sets of research equipment were purchased. The OAC cooperates with Lithuanian science and studies institutions, business sector and other governmental and public institutions. Investigations can be carried in the Geosciences, Biotaxonomy, Ecology and Molecular Research, and Ecotoxicology fields. Environmental radioactivity, radioecology, nuclear geophysics, microscopic and chemical composition of natural compounds (minerals, rocks etc.), paleomagnetic, magnetic and environmental investigations, as well as ground and water contamination by oil products and other organic environment polluting compounds, identification of fossils, rocks and minerals can be studied in the Georesearch field. Ecosystems and identification of plants, animals and microorganisms are main subjects of the Biotaxonomy, Ecology and Molecular Research field. The Ecotoxicologal Research deals with toxic and genotoxic effects of toxic substances and other sources of pollution on macro- and microorganisms and cell cultures. Open access is guaranteed by: (1) providing scientific research and experimental development services; (2) implementing joint business and science projects; (3) using facilities for the training of specialists of the highest qualifications; (4) providing properly qualified and technically trained users with opportunities to carry out their scientific research and/or experiments in the OAC laboratories by themselves. Services provided in the Open Access Centre can be received by both internal and external users: persons undertaking innovative economic activities, students of other educational institutions, interns, external teams of researchers engaged in scientific research activities, teachers

  20. Avoiding legal pitfalls in surrogacy arrangements.

    PubMed

    James, Summer; Chilvers, Rebecca; Havemann, Dara; Phelps, John Y

    2010-12-01

    The goal of this article is to discuss the legal pitfalls that reproductive endocrinologists face when participating in gestational surrogacy contracts. This paper was composed using Westlaw and LexisNexis commercial legal search engines to perform a review of statutes and cases pertaining to gestational surrogacy. The search results demonstrated that in the absence of suitable preparation, there is significant potential for litigation while participating in gestational agreements. Providers caring for gestational carriers have been named as parties in lawsuits for failure to provide psychological screening, failure to screen for infectious disease and participation in gestational contracts that are not compliant with state law. There is great disparity in state laws and court rulings pertaining to gestational agreements. When legal disputes arise, individual state laws and court rulings are controlling over the Uniform Parentage Act. Likewise, recommendations by the American College of Obstetricians and Gynecologists and the American Society for Reproductive Medicine do not supersede state laws. The failure to abide by individual state laws unnecessarily exposes reproductive endocrinologists and their IVF facilities to potential litigation. In order to lessen exposure to litigation, an understanding of individual state legislation or historical court rulings is advised. PMID:21050815

  1. Avoiding numerical pitfalls in social force models

    NASA Astrophysics Data System (ADS)

    Köster, Gerta; Treml, Franz; Gödel, Marion

    2013-06-01

    The social force model of Helbing and Molnár is one of the best known approaches to simulate pedestrian motion, a collective phenomenon with nonlinear dynamics. It is based on the idea that the Newtonian laws of motion mostly carry over to pedestrian motion so that human trajectories can be computed by solving a set of ordinary differential equations for velocity and acceleration. The beauty and simplicity of this ansatz are strong reasons for its wide spread. However, the numerical implementation is not without pitfalls. Oscillations, collisions, and instabilities occur even for very small step sizes. Classic solution ideas from molecular dynamics do not apply to the problem because the system is not Hamiltonian despite its source of inspiration. Looking at the model through the eyes of a mathematician, however, we realize that the right hand side of the differential equation is nondifferentiable and even discontinuous at critical locations. This produces undesirable behavior in the exact solution and, at best, severe loss of accuracy in efficient numerical schemes even in short range simulations. We suggest a very simple mollified version of the social force model that conserves the desired dynamic properties of the original many-body system but elegantly and cost efficiently resolves several of the issues concerning stability and numerical resolution.

  2. Setting dietary intake levels: problems and pitfalls.

    PubMed

    Russell, Robert M

    2007-01-01

    Recommended dietary intake levels are the nutrient standards used in designing food assistance programmes, institutional feeding programmes, counselling and teaching. In the USA, the recommended dietary allowances (RDAs) are the basis for setting the poverty threshold and food stamp allotments. In the 1990s, a new paradigm was put forth for estimating nutrient requirements and recommended intake levels. This considered the level of nutrient needed for normal body functioning (versus the amount needed to prevent a deficiency state from occurring). An estimated average requirement (EAR), an RDA and a tolerable upper intake level (UL) were determined for most nutrients. In setting forth these nutrient intake levels (dietary reference intakes, DRIs), a number of data challenges were encountered. For example, it was recognized that for most nutrients there was an absence of dose-response data, and few chronic human or animal studies had been undertaken. In considering how to revise nutrient intake recommendations for populations in the future, the following pitfalls must be overcome: (1) invalid assumption that a threshold level for a requirement will hold for all nutrients; (2) lack of uniform criteria for the selection of the endpoints used (need for evidence-based review, consideration of comparative risk); (3) invalid extrapolations to children for many nutrients; (4) lack of information on variability of responses, and interactions with other nutrients; and (5) lack of understanding in the community of how to use the various DRI numbers. PMID:17913222

  3. Pitfalls in PET/CT imaging

    NASA Astrophysics Data System (ADS)

    Rondogianni, Ph; Papathanasiou, N.; Giannopoulou, Ch

    2011-09-01

    PET with 2-[fluorine 18] fluoro-2-deoxy-d-glucose (FDG), has been a clinical tool for the evaluation of various cancers providing valuable metabolic information clinically helpful in the diagnosis, initial staging, therapy monitoring and restaging. However, FDG is not specific for neoplastic processes. Unless anatomic correlation is available to delineate normal structures, pathologic sites of FDG accumulation can easily be confused with normal physiological uptake, leading to false-positive or false-negative findings. Coregistration of PET scans (functional and morphologic information) with computed tomographic (CT) scans (anatomic information) using a combined PET-CT scanner improves the overall sensitivity and specificity of information provided by PET or CT alone. In this paper, we discuss the probable causes of false negative images and pitfalls due to technical reasons, inflammatory processes or benign lesions as well as the utility of PET-CT in differentiating malignant from inflammatory and benign processes, since in some cases such differentiation cannot be made, with certainty, using FDG PET alone.

  4. Core biopsies of the breast: diagnostic pitfalls.

    PubMed

    Joshi, Megha; Reddy, Sriharshan J; Nanavidekar, Manjiri; Russo, John P; Russo, Armand V; Pathak, Ram

    2011-01-01

    The incidence of breast cancer is increasing worldwide. In this review article, the authors compare and contrast the incidence of breast cancer, and the inherent differences in the United States (US) and India in screening techniques used for diagnosing breast cancer. In spite of these differences, core biopsies of the breast are common for diagnosis of breast cancer in both countries. The authors describe "Best Practices" in the reporting and processing of core biopsies and in the analysis of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor Receptor 2 (Her2/neu). The pitfalls in the diagnosis of fibroepithelial lesions of the breast on core biopsy are discussed, as also the significance of pseudoangiomatous stromal hyperplasia of the breast (PASH) is discussed in core biopsy. In this review, the management and diagnosis of flat epithelial atypia and radiation atypia are elaborated and the use of immunohistochemistry (IHC) in papillary lesions, phyllodes tumor, and complex sclerosing lesions (radial scars) is illustrated. Rarer lesions such as mucinous and histiocytoid carcinoma are also discussed. PMID:22234089

  5. Esophageal Impedance Monitoring: Clinical Pearls and Pitfalls.

    PubMed

    Ravi, Karthik; Katzka, David A

    2016-09-01

    The development of intraluminal esophageal impedance monitoring has improved our ability to detect and measure gastroesophageal reflux without dependence on acid content. This ability to detect previously unrecognized weak or nonacid reflux episodes has had important clinical implications in the diagnosis and management of gastroesophageal reflux disease (GERD). In addition, with the ability to assess bolus transit within the esophageal lumen, impedance monitoring has enhanced the recognition and characterization of esophageal motility disorders in patients with nonobstructive dysphagia. The assessment of the intraluminal movement of gas and liquid has also been proven to be of diagnostic value in conditions such as rumination syndrome and excessive belching. Further, alternative applications of impedance monitoring, such as the measurement of mucosal impedance, have provided novel insights into assessing esophageal mucosal integrity changes as a consequence of inflammatory change. Future applications for esophageal impedance monitoring also hold promise in esophageal conditions other than GERD. However, despite all of the clinical benefits afforded by esophageal impedance monitoring, important clinical and technical shortcomings limit its diagnostic value and must be considered when interpreting study results. Overinterpretation of studies or application of impedance monitoring in patients can have deleterious clinical implications. This review will highlight the clinical benefits and limitations of esophageal impedance monitoring and provide clinical pearls and pitfalls associated with this technology. PMID:27325223

  6. Avoiding numerical pitfalls in social force models.

    PubMed

    Köster, Gerta; Treml, Franz; Gödel, Marion

    2013-06-01

    The social force model of Helbing and Molnár is one of the best known approaches to simulate pedestrian motion, a collective phenomenon with nonlinear dynamics. It is based on the idea that the Newtonian laws of motion mostly carry over to pedestrian motion so that human trajectories can be computed by solving a set of ordinary differential equations for velocity and acceleration. The beauty and simplicity of this ansatz are strong reasons for its wide spread. However, the numerical implementation is not without pitfalls. Oscillations, collisions, and instabilities occur even for very small step sizes. Classic solution ideas from molecular dynamics do not apply to the problem because the system is not Hamiltonian despite its source of inspiration. Looking at the model through the eyes of a mathematician, however, we realize that the right hand side of the differential equation is nondifferentiable and even discontinuous at critical locations. This produces undesirable behavior in the exact solution and, at best, severe loss of accuracy in efficient numerical schemes even in short range simulations. We suggest a very simple mollified version of the social force model that conserves the desired dynamic properties of the original many-body system but elegantly and cost efficiently resolves several of the issues concerning stability and numerical resolution. PMID:23848804

  7. Principles and pitfalls of nerve conduction studies.

    PubMed

    Kimura, J

    1984-10-01

    This report reviews the fundamental principles and the changing concepts of nerve stimulation techniques, and discusses the proper application of these techniques in the differential diagnosis of peripheral nerve disorders. Nerve conduction studies help delineate the extent and distribution of the neural lesion and distinguish two major categories of peripheral nerve disease: demyelination and axonal degeneration. Although the method is based on simple principles, pitfalls abound in practice. Variability in nerve conduction measurement may result from temperature change, variations among nerve segments, and the effects of age. Other sources of error include excessive spread of stimulation current, anomalous innervation, temporal dispersion, and inaccuracy of surface measurement. Unlike a bipolar derivation, which selectively records near-field potentials, a referential recording may give rise to stationary far-field peaks from a moving source. Overlooking this possibility can lead to an incorrect interpretation of findings. Conventional nerve conduction studies deal primarily with measurements of the distal nerve segments in an extremity. More recent techniques are applicable to less accessible anatomical regions, as illustrated by elicitation of the blink reflex, F wave, and H reflex, and the use of the inching technique. Other methods used to assess special aspects of nerve conduction include the ischemic test and studies of slow-conducting fibers. PMID:6093680

  8. A Secure Web Application Providing Public Access to High-Performance Data Intensive Scientific Resources - ScalaBLAST Web Application

    SciTech Connect

    Curtis, Darren S.; Peterson, Elena S.; Oehmen, Chris S.

    2008-05-04

    This work presents the ScalaBLAST Web Application (SWA), a web based application implemented using the PHP script language, MySQL DBMS, and Apache web server under a GNU/Linux platform. SWA is an application built as part of the Data Intensive Computer for Complex Biological Systems (DICCBS) project at the Pacific Northwest National Laboratory (PNNL). SWA delivers accelerated throughput of bioinformatics analysis via high-performance computing through a convenient, easy-to-use web interface. This approach greatly enhances emerging fields of study in biology such as ontology-based homology, and multiple whole genome comparisons which, in the absence of a tool like SWA, require a heroic effort to overcome the computational bottleneck associated with genome analysis. The current version of SWA includes a user account management system, a web based user interface, and a backend process that generates the files necessary for the Internet scientific community to submit a ScalaBLAST parallel processing job on a dedicated cluster.

  9. Does the Sun revolve around the Earth? A comparison between the general public and online survey respondents in basic scientific knowledge.

    PubMed

    Cooper, Emily A; Farid, Hany

    2016-02-01

    We conducted an online survey using a set of factual science questions that are commonly administered to assess fact-based scientific literacy. We report that the online population performed substantially better on this standard assessment than the traditional survey population. For example, it has been widely reported that 1 in 4 Americans does not know that the Earth revolves around the Sun, whereas among the online population, this ratio is reduced to 1 in 25. While new online platforms provide researchers with unprecedented ease of access to a large sample population for studying trends in public knowledge and attitudes, generalizing from online population samples to the US population at large poses a considerable challenge. We discuss the potential reasons for this discrepancy and the implications for conducting research online. PMID:25324336

  10. Academic Debate: Publications Which Promote Political Agendas Have no Place in Scientific and Medical Journals, and Academics Should Refrain from Publishing in Such Journals

    PubMed Central

    Glick, Shimon; Clarfield, A. Mark; Strous, Rael D.; Horton, Richard

    2015-01-01

    This paper presents the full debate held on October 1, 2014, which focused on the following resolution: “Publications which promote political agendas have no place in scientific and medical journals, and academics should refrain from publishing in such journals.” The debate moderator was Professor Shimon Glick. Taking the pro stance was Professor A. Mark Clarfield; the con stance was held by Professor Rael D. Strous. Following the first part of the debate, Dr Richard Horton, Editor-in-Chief of The Lancet, gave his thoughts on the topic. This was followed by the opportunity for rebuttal by Professors Clarfield and Strous. The debate was summarized and closed by Professor Glick. This paper provides a slightly edited text of the debate, for ease of reading. PMID:25717385

  11. Pitfalls and optimal approaches to diagnose melioidosis.

    PubMed

    Kingsley, Paul Vijay; Arunkumar, Govindakarnavar; Tipre, Meghan; Leader, Mark; Sathiakumar, Nalini

    2016-06-01

    Melioidosis is a severe and fatal infectious disease in the tropics and subtropics. It presents as a febrile illness with protean manifestation ranging from chronic localized infection to acute fulminant septicemia with dissemination of infection to multiple organs characterized by abscesses. Pneumonia is the most common clinical presentation. Because of the wide range of clinical presentations, physicians may often misdiagnose and mistreat the disease for tuberculosis, pneumonia or other pyogenic infections. The purpose of this paper is to present common pitfalls in diagnosis and provide optimal approaches to enable early diagnosis and prompt treatment of melioidosis. Melioidosis may occur beyond the boundaries of endemic areas. There is no pathognomonic feature specific to a diagnosis of melioidosis. In endemic areas, physicians need to expand the diagnostic work-up to include melioidosis when confronted with clinical scenarios of pyrexia of unknown origin, progressive pneumonia or sepsis. Radiological imaging is an integral part of the diagnostic workup. Knowledge of the modes of transmission and risk factors will add support in clinically suspected cases to initiate therapy. In situations of clinically highly probable or possible cases where laboratory bacteriological confirmation is not possible, applying evidence-based criteria and empirical treatment with antimicrobials is recommended. It is of prime importance that patients undergo the full course of antimicrobial therapy to avoid relapse and recurrence. Early diagnosis and appropriate management is crucial in reducing serious complications leading to high mortality, and in preventing recurrences of the disease. Thus, there is a crucial need for promoting awareness among physicians at all levels and for improved diagnostic microbiology services. Further, the need for making the disease notifiable and/or initiating melioidosis registries in endemic countries appears to be compelling. PMID:27262061

  12. On the pitfalls of peer review

    PubMed Central

    van Gunsteren, Wilfred

    2015-01-01

    The review process of academic, scientific research and its basic tenets is considered, thereby distinguishing between (i) reviewing of manuscripts to be published in the scientific literature, (ii) reviewing of research proposals to be financed by funding agencies, (iii) reviewing of educational or research institutions with respect to their proper functioning, and (iv) reviewing of scientists with the aim of appointing or tenuring faculty. PMID:26675931

  13. How to avoid the ten most frequent EMS pitfalls

    SciTech Connect

    Andrews, W.

    1982-04-19

    It pays to do your homework before investing in an energy management system if you want to avoid the 10 most common pitfalls listed by users, consultants, and manufacturers as: oversimplification, improper maintenance, failure to involve operating personnel, inaccurate savings estimates, failure to include monitoring capability, incompetent or fradulent firms, improper load control, not allowing for a de-bugging period, failure to include manual override, and software problems. The article describes how each of these pitfalls can lead to poor decisions and poor results. (DCK)

  14. [Principles and criteria used by the National Evaluation Committee of Research Activity (CNEAI-Spain) for the assessment of scientific publications: 1989-2009].

    PubMed

    Ruiz-Pérez, Rafael; Delgado López-Cózar, Emilio; Jiménez-Contreras, Evaristo

    2010-11-01

    Study of the origins, philosophy and history of the criteria used to assess research activities in Spain by the CNEAI. The assessment criteria and quality evidence of publications is discussed. Results are presented on the temporal development of the criteria used, grouped by publication type (articles and books) and fields of knowledge. Between 1989-1996, assessment was based on the definition and goals set by the Spanish scientific framework and on general criteria. Between 1996-2004, the formulation of indicators began to be almost exclusively based on Journal Citation Reports (JCR). Success rates up to 2004 indicate that the evaluation criteria and publishing behaviour matched the "hard sciences", but not the Social Sciences and Economics. In 2005, the criteria used were further developed and reoriented with an eye to softening the preceding JCR-centrism by taking into consideration other databases and defining the quality criteria to be met by journals, books and conferences not included in JCR. Correspondingly, the success rates for 2007 indicate a dramatic recovery in Economics. In the last 4 years, Humanities and Social Sciences have consolidated the further opening of the criteria used with the addition of new benchmarks and the full integration of books. PMID:21044530

  15. Pitfalls in statistical landslide susceptibility modelling

    NASA Astrophysics Data System (ADS)

    Schröder, Boris; Vorpahl, Peter; Märker, Michael; Elsenbeer, Helmut

    2010-05-01

    The use of statistical methods is a well-established approach to predict landslide occurrence probabilities and to assess landslide susceptibility. This is achieved by applying statistical methods relating historical landslide inventories to topographic indices as predictor variables. In our contribution, we compare several new and powerful methods developed in machine learning and well-established in landscape ecology and macroecology for predicting the distribution of shallow landslides in tropical mountain rainforests in southern Ecuador (among others: boosted regression trees, multivariate adaptive regression splines, maximum entropy). Although these methods are powerful, we think it is necessary to follow a basic set of guidelines to avoid some pitfalls regarding data sampling, predictor selection, and model quality assessment, especially if a comparison of different models is contemplated. We therefore suggest to apply a novel toolbox to evaluate approaches to the statistical modelling of landslide susceptibility. Additionally, we propose some methods to open the "black box" as an inherent part of machine learning methods in order to achieve further explanatory insights into preparatory factors that control landslides. Sampling of training data should be guided by hypotheses regarding processes that lead to slope failure taking into account their respective spatial scales. This approach leads to the selection of a set of candidate predictor variables considered on adequate spatial scales. This set should be checked for multicollinearity in order to facilitate model response curve interpretation. Model quality assesses how well a model is able to reproduce independent observations of its response variable. This includes criteria to evaluate different aspects of model performance, i.e. model discrimination, model calibration, and model refinement. In order to assess a possible violation of the assumption of independency in the training samples or a possible

  16. Performing renography in children with antenatally detected pelvi-ureteric junction stenosis: errors, pitfalls, controversies.

    PubMed

    Piepsz, A; Sixt, R; Gordon, I

    2010-08-01

    The aim of this work is to present to the reader the practical experience of three clinicians having actively participated to the publication of the guidelines on renography in children. The present publication should be considered as a practical guide. We have underlined good practice, obvious errors to avoid, common pitfalls which might be overlooked, some items for which more than one reasonable solution exists and finally a few controversial points, for which there is still no agreement and no solid evidence to resolve these issues. This paper is only focused on the aspects of acquisition and processing and will not cover the clinical aspects, namely the interpretation of the renogram in terms of renal obstruction or, more precisely, in terms of risk of renal deterioration. PMID:20823803

  17. Payoffs and Pitfalls of a Minority Outreach Program: An Alaskan Example

    NASA Astrophysics Data System (ADS)

    Hanks, C. L.; Fowell, S. J.; Wartes, D.; Owens, G.

    2004-12-01

    The Rural Alaska Honors Institute (RAHI) is a summer bridging program for college-bound high school students from remote Alaskan communities. In the 20+ years since its initiation, more than 50% of RAHI graduates eventually obtained post-secondary degrees. The success of the RAHI program provides insights into how an outreach program can achieve its goals and avoid potential pitfalls. Instrumental to the success of the RAHI program are: longevity; small size (40-45 students per summer); support from the Alaska Native community; academic rigor; aggressive recruiting; establishment of a sense of community amongst participants; and individual mentoring and support. Potential pitfalls include: overextending the program to include too many students; failure to maintain academic rigor in all courses; recruitment of students and staff who do not embrace the program's methods and goals; and attempts to evaluate the program on the basis of short-term results. Alaska Natives in Geosciences introduces college-bound Alaska Native students to the geosciences by teaching a college-level introductory geoscience class as a RAHI elective. By collaborating with RAHI, Alaska Natives in Geosciences takes advantage of RAHI's effective recruitment efforts and proven mentoring program. However, maintaining scientific rigor has been difficult due to large differences in the students' scientific backgrounds, the demands of other courses in the RAHI program and the brevity of the summer session. Immediate post-course survey responses suggest that many RAHI students thought the geoscience class was interesting but too difficult and much too time-consuming. However, surveys of RAHI geoscience students a year later suggest that many found the course a very positive experience. An unanticipated result was that RAHI students who did not take the class also gained some insight into the geosciences.

  18. Geochemical databases: minding the pitfalls to avoid the pratfalls

    NASA Astrophysics Data System (ADS)

    Goldstein, S. L.; Hofmann, A. W.

    2011-12-01

    The field of geochemistry has been revolutionized in recent years by the advent of databases (PetDB, GEOROC, NAVDAT, etc). A decade ago, a geochemical synthesis required major time investments in order to compile relatively small amounts of fragmented data from large numbers of publications, Now virtually all of the published data on nearly any solid Earth topic can be downloaded to nearly any desktop computer with a few mouse clicks. Most solid Earth talks at international meetings show data compilations from these databases. Applications of the data are playing an increasingly important role in shaping our thinking about the Earth. They have changed some fundamental ideas about the compositional structure of the Earth (for example, showing that the Earth's "trace element depleted upper mantle" is not so depleted in trace elements). This abundance of riches also poses new risks. Until recently, important details associated with data publication (adequate metadata and quality control information) were given low priority, even in major journals. The online databases preserve whatever has been published, irrespective of quality. "Bad data" arises from many causes, here are a few. Some are associated with sample processing, including incomplete dissolution of refractory trace minerals, or inhomogeneous powders, or contamination of key elements during preparation (for example, this was a problem for lead when gasoline was leaded, and for niobium when tungsten-carbide mills were used to powder samples). Poor analytical quality is a continual problem (for example, when elemental abundances are at near background levels for an analytical method). Errors in published data tables (more common than you think) become bad data in the databases. The accepted values of interlaboratory standards change with time, while the published data based on old values stay the same. Thus the pitfalls associated with the new data accessibility are dangerous in the hands of the inexperienced

  19. A comparison of pitfall traps with bait traps for studying leaf litter ant communities.

    PubMed

    Wang, C; Strazanac, J; Butler, L

    2001-06-01

    A comparison of pitfall traps with bait traps for sampling leaf litter ants was studied in oak-dominated mixed forests during 1995-1997. A total of 31,732 ants were collected from pitfall traps and 54,694 ants were collected from bait traps. They belonged to four subfamilies, 17 genera, and 32 species. Bait traps caught 29 species, whereas pitfall traps caught 31 species. Bait traps attracted one species not found in pitfall traps, but missed three of the species collected with pitfall traps. Collections from the two sampling methods showed differences in species richness, relative abundance, diversity, and species accumulation curves. Pitfall traps caught significantly more ant species per plot than did bait traps. The ant species diversity obtained from pitfall traps was higher than that from bait traps. Bait traps took a much longer time to complete an estimate of species richness than did pitfall traps. Little information was added to pitfall trapping results by the bait trapping method. The results suggested that the pitfall trapping method is superior to the bait trapping method for leaf litter ant studies. Species accumulation curves showed that sampling of 2,192+/-532 ants from six plots by pitfall traps provided a good estimation of ant species richness under the conditions of this study. PMID:11425034

  20. Pitfalls and Limitations of Radionuclide Imaging in Endocrinology.

    PubMed

    Agrawal, Kanhaiyalal; Esmail, Abdulredha A H; Gnanasegaran, Gopinath; Navalkissoor, Shaunak; Mittal, Bhagwant Rai; Fogelman, Ignac

    2015-09-01

    Several different techniques, radiopharmaceuticals, and imaging modalities are commonly used in nuclear medicine for studies of endocrine organs. Nuclear medicine is used in the management of benign and malignant thyroid, parathyroid, and neuroendocrine disorders. Thus, it is essential to acknowledge pitfalls and the limitations of nuclear medicine imaging for accurate diagnosis and patient management. PMID:26278855

  1. Five pitfalls of work redesign in acute care.

    PubMed

    Seago, J A

    1997-10-01

    During work redesign in nursing units, five common pitfalls can emerge: moving too fast, failing to involve major stakeholders, discounting bargaining unit contracts, separating training classes and not defining desired outcomes. Suggestions on how to avoid these problems are given. PMID:9369723

  2. REVIEW ARTICLE: EIT reconstruction algorithms: pitfalls, challenges and recent developments

    NASA Astrophysics Data System (ADS)

    Lionheart, William R. B.

    2004-02-01

    We review developments, issues and challenges in electrical impedance tomography (EIT) for the 4th Conference on Biomedical Applications of Electrical Impedance Tomography, held at Manchester in 2003. We focus on the necessity for three-dimensional data collection and reconstruction, efficient solution of the forward problem, and both present and future reconstruction algorithms. We also suggest common pitfalls or 'inverse crimes' to avoid.

  3. Cases on Global E-Learning Practices: Successes and Pitfalls

    ERIC Educational Resources Information Center

    Sharma, Ramesh C., Ed.; Mishra, Sanjaya, Ed.

    2007-01-01

    "Cases on Global E-Learning Practices: Successes and Pitfalls" looks into global practices of e-learning, examining the successes and failures of e-learning professionals. It provides a judicious mix of practical experiences and research in the form of case studies. Written by experts from all over the globe, this book shows how to design…

  4. E-Content Development for Languages: Success Factors and Pitfalls

    ERIC Educational Resources Information Center

    De Paepe, Liesbeth

    2014-01-01

    This paper discusses the success factors and pitfalls in development of e-content for languages. The factors discussed draw on several years of experience in developing and implementing 95% distance courses for Dutch as a second language in the adult education sector in Flanders and on PhD research at VUB. The CEFR [Common European Framework of…

  5. The Pitfalls and Triumphs of Launching a Charter School.

    ERIC Educational Resources Information Center

    Page, Linda; Levine, Mark

    1996-01-01

    A principal of a charter school in Colorado Springs, Colorado, recounts the triumphs and pitfalls of the school's first year. The school charter lacked a clear-cut avenue for making changes. Intending to create a parent-run school, the founding board (themselves parents) made drastic curricular changes without consulting other parents. Passionate…

  6. How Environmental "Merchants of Doubt" Use Peer-Reviewed Publication as a Means to Commandeer Scientific Debate: A Case Study of a Publishing Problem.

    NASA Astrophysics Data System (ADS)

    Siegel, D. I.

    2015-12-01

    This year, the USEPA reported no systemic problem with respect to pollution of potable waters by solutes or natural gas resulting from unconventional drilling for oil and gas, despite attempts by anti-fracking opponents to frighten the public about water pollution from rare circumstances (much as those who have cherry- picked climate data to suggest burning fossil fuels does not affect climate). Scientific "merchants of doubt" have figured out how to use peer-reviewed papers to advocate their bias, regardless of the side for which they advocate. I present a personal example. Prior to the EPA report, authors of a highly-cited peer-reviewed paper argued that more dissolved methane than usual should be expected in ground water located close to unconventional gas wells. This paper figured prominently in the New York State's recent ban on fracking. To test the reproducibility of this conclusion, colleagues and I redid the study but by sampling ~13,000 NE Pennsylvania domestic wells, densely arrayed near ~800 gas wells. Not surprising, we found no systemic relationship between methane in drinking water and proximity to gas wells; failed gas wells actually are rare. The peer reviewed system of publication has been broken for years, because of continual pressure to publish more to achieve academic success coupled to a flood of international submissions. Editors routinely have a difficult time finding senior scientists to agree to review papers, and so they wind up relying more on reviewers suggested by authors, who can and have gamed the peer review system through it. To resolve this problem, I suggest that journal editors be more far more draconian before releasing papers for review and that they enforce clear rubrics to insure that reviewers address reviews properly. Finally, conflict of interest disclosure needs to be clearer, since common assumption that bias inherently evolves from funded research outside of Federal and non-profit organizations, appears to be, at

  7. [Floods and public health: a review of the recent scientific literature on the causes, consequences and responses to prevention and mitigation].

    PubMed

    de Freitas, Carlos Machado; Ximenes, Elisa Francioli

    2012-06-01

    Floods are among the most frequent natural disasters and they affect the lives of approximately 102 million people each year, mainly in developing countries and in major urban areas with a tendency to grow further over the coming decades. The scope of this paper is to provide input for a clearer understanding of these events through the results and experiences to be gleaned from the recent scientific literature. From the Pubmed database, 70 articles were analyzed that fulfilled the criteria to address at least one of the items selected for analysis, namely: 1) causes; 2) consequences; 3) responses and actions: submission of proposals and solutions for the prevention and/or mitigation of the risks and impacts of flooding. Tables for each of the items selected were organized in order to systematize and synthesize the results for causes (attributed to natural and human activities); environmental, infrastructure and services, and health consequences (injuries and diseases classified according to chapters of ICD-10); prevention and mitigation responses and actions. It was concluded that given the scenarios of increased frequency and severity of these events, the challenges facing public health for disaster risk reduction require integrated responses with broad policies for sustainable development. PMID:22699650

  8. Scientific integrity memorandum

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2009-03-01

    U.S. President Barack Obama signed a presidential memorandum on 9 March to help restore scientific integrity in government decision making. The memorandum directs the White House Office of Science and Technology Policy to develop a strategy within 120 days that ensures that "the selection of scientists and technology professionals for science and technology positions in the executive branch is based on those individuals' scientific and technological knowledge, credentials, and experience; agencies make available to the public the scientific or technological findings or conclusions considered or relied upon in policy decisions; agencies use scientific and technological information that has been subject to well-established scientific processes such as peer review; and agencies have appropriate rules and procedures to ensure the integrity of the scientific process within the agency, including whistleblower protection."

  9. Perspectives and Pitfalls in Nucleic Acids Crystallography.

    PubMed

    Westhof, Eric

    2016-01-01

    X-ray crystallography offers precious and striking knowledge on biomolecular architectures. Although safeguards do exist to guarantee the accuracy of the structures deposited in databases, they are not always applied, leading to the spread of inaccurate data. The importance of validation reports in the publication process is emphasized. PMID:26227033

  10. Mainstreaming: The Promise and the Pitfalls.

    ERIC Educational Resources Information Center

    Longo, Paul

    1982-01-01

    Hails the potential that mainstreaming of the handicapped holds for developing individual potential and enhancing equal educational opportunity, but cautions that extensive retraining of staff and diversification of teaching strategies will be necessary if adequate implementation of Public Law 94-142 is to be achieved. (GC)

  11. Three-piece Inflatable Penile Prosthesis: Surgical Techniques and Pitfalls

    PubMed Central

    Al-Enezi, Ahmad; Al-Khadhari, Sulaiman; Al-Shaiji, Tariq F.

    2011-01-01

    Penile prosthesis surgery plays a vital role in the treatment of erectile dysfunction (ED). As far as outcome is concerned, it is one of the most rewarding procedures for both patients and surgeons. We describe our surgical technique for implantation of the three-piece inflatable penile prosthesis and point out the major surgical pitfalls accompanying this procedure and their specific management. The psychological outcome of penile prosthesis surgery is also discussed. Different surgical approaches are available when performing the procedure. A number of procedure-related problems can be encountered and a thorough knowledge of these is of paramount importance. Penile prosthesis surgery has a favorable psychological outcome. Surgery for implantation of an inflatable penile prosthesis is a rewarding procedure, with a high yield of patient satisfaction. Urologists should have thorough understanding of the surgical pitfalls peculiar to this procedure and their management. PMID:22413049

  12. Herpetological Monitoring Using a Pitfall Trapping Design in Southern California

    USGS Publications Warehouse

    Fisher, Robert; Stokes, Drew; Rochester, Carlton; Brehme, Cheryl; Hathaway, Stacie; Case, Ted

    2008-01-01

    The steps necessary to conduct a pitfall trapping survey for small terrestrial vertebrates are presented. Descriptions of the materials needed and the methods to build trapping equipment from raw materials are discussed. Recommended data collection techniques are given along with suggested data fields. Animal specimen processing procedures, including toe- and scale-clipping, are described for lizards, snakes, frogs, and salamanders. Methods are presented for conducting vegetation surveys that can be used to classify the environment associated with each pitfall trap array. Techniques for data storage and presentation are given based on commonly use computer applications. As with any study, much consideration should be given to the study design and methods before beginning any data collection effort.

  13. Modeling emission from the first explosions: pitfalls and problems

    SciTech Connect

    Fryer, Christopher Lee; Whalen, Daniel J; Frey, Lucille H

    2010-01-01

    Observations of the explosions of the population III stars have the potential to teach us much about the formation and evolution of these zero metallicity objects. But to reach this potential, we must tie the observed emission to and explosion model. This requires accurate light-curve/spectral calculations. Here we discuss many of the pitfalls and problems involved in such calculations, presenting some preliminary results from radiation-hydrodynamics calculations.

  14. Using demographic data to better interpret pitfall trap catches

    PubMed Central

    Matalin, Andrey V.; Makarov, Kirill V.

    2011-01-01

    Abstract The results of pitfall trapping are often interpreted as abundance in a particular habitat. At the same time, there are numerous cases of almost unrealistically high catches of ground beetles in seemingly unsuitable sites. The correlation of catches by pitfall trapping with the true distribution and abundance of Carabidae needs corroboration. During a full year survey in 2006/07 in the Lake Elton region (Volgograd Area, Russia), 175 species of ground beetles were trapped. Considering the differences in demographic structure of the local populations, and not their abundances, three groups of species were recognized: residents, migrants and sporadic. In residents, the demographic structure of local populations is complete, and their habitats can be considered “residential”. In migrants and sporadic species, the demographic structure of the local populations is incomplete, and their habitats can be considered “transit”. Residents interact both with their prey and with each other in a particular habitat. Sporadic species are hardly important to a carabid community because of their low abundances. The contribution of migrants to the structure of carabid communities is not apparent and requires additional research. Migrants and sporadic species represent a “labile” component in ground beetles communities, as opposed to a “stable” component, represented by residents. The variability of the labile component substantially limits our interpretation of species diversity in carabid communities. Thus, the criteria for determining the most abundant, or dominant species inevitably vary because the abundance of migrants in some cases can be one order of magnitude higher than that of residents. The results of pitfall trapping adequately reflect the state of carabid communities only in zonal habitats, while azonal and disturbed habitats are merely transit ones for many species of ground beetles. A study of the demographic structure of local populations and

  15. Pitfall in MR imaging of lymphadenopathy after lymphangiography.

    PubMed

    Buckwalter, K A; Ellis, J H; Baker, D E; Borello, J A; Glazer, G M

    1986-12-01

    In two patients examined with magnetic resonance (MR) imaging after lymphangiography, opacified pelvic lymph nodes could not be distinguished from subcutaneous or retroperitoneal fat because of the short T1 and long T2 relaxation times of lymphangiographic contrast media. Opacified nodes removed from one patient had relaxation times similar to those of fat. Thus, assessment of lymphadenopathy with MR imaging should be performed before lymphangiography to obviate this potential pitfall. PMID:3024208

  16. [Suture foreign body reaction as a mammographic pitfall].

    PubMed

    Plagborg, G J; Andersen, H K

    2000-02-14

    A mammographic pitfall is presented. After lumpectomy owing to cancer in the breast a woman developed an immediate allergic reaction presumably caused by the subcutaneous sutures (vicryl). After adjuvant irradiation the breast became swollen and mammography gave suspicion of a recurrent breast cancer. Surgical excision was performed and examination of the biopsy specimen showed a foreign body reaction to the suture material with fibrosis and eosinophilia. PMID:10740437

  17. Industry Support of Medical Research: Important Opportunity or Treacherous Pitfall?

    PubMed

    Tierney, William M; Meslin, Eric M; Kroenke, Kurt

    2016-02-01

    Pharmaceutical and device manufacturers fund more than half of the medical research in the U.S. Research funding by for-profit companies has increased over the past 20 years, while federal funding has declined. Research funding from for-profit medical companies is seen as tainted by many academicians because of potential biases and prior misbehavior by both investigators and companies. Yet NIH is encouraging partnerships between the public and private sectors to enhance scientific discovery. There are instances, such as methods for improving drug adherence and post-marketing drug surveillance, where the interests of academician researchers and industry could be aligned. We provide examples of ethically performed industry-funded research and a set of principles and benchmarks for ethically credible academic-industry partnerships that could allow academic researchers, for-profit companies, and the public to benefit. PMID:26307387

  18. 78 FR 57159 - Scientific Information Request on Medication Therapy Management

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-17

    ... HUMAN SERVICES Agency for Healthcare Research and Quality Scientific Information Request on Medication... scientific information submissions. SUMMARY: The Agency for Healthcare Research and Quality (AHRQ) is seeking scientific information submissions from the public on medication therapy management Scientific information...

  19. A Washington Perspective on Women and Networking: The Power and the Pitfalls.

    ERIC Educational Resources Information Center

    Green, Madeleine F.

    1982-01-01

    Describes two successful, institutionalized networking programs of the American Council on Education. Discusses the potential benefits and pitfalls of networking especially as they apply to women. (RC)

  20. Protein crystallography for aspiring crystallographers or how to avoid pitfalls and traps in macromolecular structure determination

    PubMed Central

    Wlodawer, Alexander; Minor, Wladek; Dauter, Zbigniew; Jaskolski, Mariusz

    2014-01-01

    The number of macromolecular structures deposited in the Protein Data Bank now approaches 100 000, with the vast majority of them determined by crystallographic methods. Thousands of papers describing such structures have been published in the scientific literature, and 20 Nobel Prizes in chemistry or medicine have been awarded for discoveries based on macromolecular crystallography. New hardware and software tools have made crystallography appear to be an almost routine (but still far from being analytical) technique and many structures are now being determined by scientists with very limited experience in the practical aspects of the field. However, this apparent ease is sometimes illusory and proper procedures need to be followed to maintain high standards of structure quality. In addition, many noncrystallographers may have problems with the critical evaluation and interpretation of structural results published in the scientific literature. The present review provides an outline of the technical aspects of crystallography for less experienced practitioners, as well as information that might be useful for users of macromolecular structures, aiming to show them how to interpret (but not overinterpret) the information present in the coordinate files and in their description. A discussion of the extent of information that can be gleaned from the atomic coordinates of structures solved at different resolution is provided, as well as problems and pitfalls encountered in structure determination and interpretation. PMID:24034303

  1. Thermoregulatory Behavior in Diurnal Lizards as a Vehicle for Teaching Scientific Process

    ERIC Educational Resources Information Center

    Platz, James E.

    2009-01-01

    Field experiments offer the opportunity for hands on experience with the scientific process. While this is true of a wide variety of activities, many have pitfalls both experimental and logistical that reduce the overall rate of success, in turn, influencing student learning outcomes. Relying on small, territorial, diurnal lizards and an array of…

  2. Scientific Misconduct.

    PubMed

    Gross, Charles

    2016-01-01

    Scientific misconduct has been defined as fabrication, falsification, and plagiarism. Scientific misconduct has occurred throughout the history of science. The US government began to take systematic interest in such misconduct in the 1980s. Since then, a number of studies have examined how frequently individual scientists have observed scientific misconduct or were involved in it. Although the studies vary considerably in their methodology and in the nature and size of their samples, in most studies at least 10% of the scientists sampled reported having observed scientific misconduct. In addition to studies of the incidence of scientific misconduct, this review considers the recent increase in paper retractions, the role of social media in scientific ethics, several instructional examples of egregious scientific misconduct, and potential methods to reduce research misconduct. PMID:26273897

  3. Perils and pitfalls of reporting sex differences.

    PubMed

    Maney, Donna L

    2016-02-19

    The idea of sex differences in the brain both fascinates and inflames the public. As a result, the communication and public discussion of new findings is particularly vulnerable to logical leaps and pseudoscience. A new US National Institutes of Health policy to consider both sexes in almost all preclinical research will increase the number of reported sex differences and thus the risk that research in this important area will be misinterpreted and misrepresented. In this article, I consider ways in which we might reduce that risk, for example, by (i) employing statistical tests that reveal the extent to which sex explains variation, rather than whether or not the sexes 'differ', (ii) properly characterizing the frequency distributions of scores or dependent measures, which nearly always overlap, and (iii) avoiding speculative functional or evolutionary explanations for sex-based variation, which usually invoke logical fallacies and perpetuate sex stereotypes. Ultimately, the factor of sex should be viewed as an imperfect, temporary proxy for yet-unknown factors, such as hormones or sex-linked genes, that explain variation better than sex. As scientists, we should be interested in discovering and understanding the true sources of variation, which will be more informative in the development of clinical treatments. PMID:26833839

  4. Anticoagulant conversion in the elderly: pitfalls.

    PubMed

    Al-Nasser, Bassam

    2016-05-01

    The prevalence of medical conditions representing a risk for thromboembolic complications and requiring antithrombotic therapy increases gradually with age. Two cases of fatal noncritical organ bleeding complication that occurred during the conversion period from initial fondaparinux to vitamin K antagonist are presented. An 81-year-old obese female patient (body mass index 43 kg/m(2)) with previous postoperative thrombosis underwent uneventful total knee replacement under spinal anesthesia. She presented with popliteal hematoma during conversion to oral anticoagulant. A 92-year-old female patient (body mass index 33 kg/m(2)) with left lower limb thrombosis was referred to our orthopedics department from her senior citizens' home for right lower limb hematoma and ischemia that occurred during conversion to oral anticoagulant. Thromboembolic and bleeding events in the elderly are real public health problems. Specific guidelines dedicated to this particular population are needed, which will improve the management of anticoagulation and decrease risk of complications. PMID:26547115

  5. Investigation of the Public Library as a Linking Agent to Major Scientific, Educational, Social and Environmental Data Bases. Two-Year Interim Report.

    ERIC Educational Resources Information Center

    Summit, Roger K.; Firschein, Oscar

    Eight public libraries participated in a two-year experiment to investigate the potential of the public library as a "linking agent" between the public and the many machine-readable data bases currently accessible using on line computer terminals. The investigation covered users of the service, impact on the library, conditions for successful use…

  6. Cultural Diversity in Nursing Education: Perils, Pitfalls, and Pearls

    PubMed Central

    Bednarz, Hedi; Schim, Stephanie; Doorenbos, Ardith

    2010-01-01

    Increasing diversity in the classroom challenges nursing educators to identify issues that complicate teaching (perils), analyze barriers for themselves and their students (pitfalls), and select new strategies for working with nontraditional students (pearls). This article identifies concerns arising from attitudes and values within nursing and common approaches to diversity education, and then discusses key issues in nursing education that relate to human nature, culture, faculty workload, and student demographics. Finally, some strategies are proposed for increasing the effectiveness of professional preparation with diverse students through a focus on culturally congruent education and development of faculty cultural competence. PMID:20143759

  7. [Pitfalls in the diagnosis of occult elbow fractures in children].

    PubMed

    Courvoisier, A; Calvelli, N; Bourgeois, E; Eid, A; Griffet, J

    2016-08-01

    Elbow injuries are frequent but occult fractures are difficult to diagnose on x-rays. However, any delay in the diagnosis may severely impair the prognosis of some fractures. Simple tips may help the clinician read x-rays properly and avoid the classical pitfalls of elbow injuries in children. The chronology of appearance of ossification nuclei around the elbow is important to distinguish normal features from abnormality. Drawing simple geometric constructions on the x-rays may clarify most occult elbow fractures in children. PMID:27345552

  8. Artifacts and pitfalls in shoulder magnetic resonance imaging*

    PubMed Central

    Marcon, Gustavo Felix; Macedo, Tulio Augusto Alves

    2015-01-01

    Magnetic resonance imaging has revolutionized the diagnosis of shoulder lesions, in many cases becoming the method of choice. However, anatomical variations, artifacts and the particularity of the method may be a source of pitfalls, especially for less experienced radiologists. In order to avoid false-positive and false-negative results, the authors carried out a compilation of imaging findings that may simulate injury. It is the authors’ intention to provide a useful, consistent and comprehensive reference for both beginner residents and skilled radiologists who work with musculoskeletal magnetic resonance imaging, allowing for them to develop more precise reports and helping them to avoid making mistakes. PMID:26379323

  9. Avoiding pitfalls in simulating real-time computer systems

    NASA Technical Reports Server (NTRS)

    Smith, R. S.

    1984-01-01

    The software simulation of a computer target system on a computer host system, known as an interpretive computer simulator (ICS), functionally models and implements the action of the target hardware. For an ICS to function as efficiently as possible and to avoid certain pitfalls in designing an ICS, it is important that the details of the hardware architectural design of both the target and the host computers be known. This paper discusses both host selection considerations and ICS design features that, without proper consideration, could make the resulting ICS too slow to use or too costly to maintain and expand.

  10. The seven common pitfalls of customer service in hospitals.

    PubMed

    Domingo, Rene T

    2015-01-01

    Operating simultaneously like a repair shop, prison, and hotel, hospitals are prone to seven common pitfalls in customer service. Patient care is often fragmented, inscrutable, inflexible, insensitive, reactive, myopic, and unsafe. Hospitals are vying to be more high-tech, rather than high-touch even though staff engagement with patients rather than facilities and equipment strongly influence patient satisfaction. Unless processes, policies, and people are made customer-centered, the high quality of the hospital's human and hardware resources will not translate into high patient satisfaction and patient loyalty. PMID:26058286

  11. Imaging of facial nerve schwannomas: diagnostic pearls and potential pitfalls

    PubMed Central

    Mundada, Pravin; Purohit, Bela Satish; Kumar, Tahira Sultana; Tan, Tiong Yong

    2016-01-01

    Schwannomas are uncommon in the facial nerve and account for less than 1% of tumors of temporal bone. They can involve one or more than one segment of the facial nerve. The clinical presentations and the imaging appearances of facial nerve schwannomas are influenced by the topographical anatomy of the facial nerve and vary according to the segment(s) they involve. This pictorial essay illustrates the imaging features of facial nerve schwannomas according to their various anatomical locations and also reviews the pertinent differential diagnoses and potential diagnostic pitfalls. PMID:26712680

  12. Fluorescent Proteins in Cellular Organelles: Serious Pitfalls and Some Solutions

    PubMed Central

    Costantini, Lindsey M.

    2013-01-01

    Fluorescent proteins (FPs) have been powerful tools for cell biologists for over 15 years. The large variety of FPs available rarely comes with an instruction manual or a warning label. The potential pitfalls of the use of FPs in cellular organelles represent a significant concern for investigators. FPs generally did not evolve in the often distinctive physicochemical environments of subcellular organelles. In organelles, FPs can misfold, go dark, and even distort organelle morphology. In this minireview, we describe the issues associated with FPs in organelles and provide solutions to enable investigators to better exploit FP technology in cells. PMID:23971632

  13. Principles and Pitfalls: a Guide to Death Certification

    PubMed Central

    Brooks, Erin G.; Reed, Kurt D.

    2015-01-01

    Death certificates serve the critical functions of providing documentation for legal/administrative purposes and vital statistics for epidemiologic/health policy purposes. In order to satisfy these functions, it is important that death certificates be filled out completely, accurately, and promptly. The high error rate in death certification has been documented in multiple prior studies, as has the effectiveness of educational training interventions at mitigating errors. The following guide to death certification is intended to illustrate some basic principles and common pitfalls in electronic death registration with the goal of improving death certification accuracy. PMID:26185270

  14. Epidemiological designs for vaccine safety assessment: methods and pitfalls.

    PubMed

    Andrews, Nick

    2012-09-01

    Three commonly used designs for vaccine safety assessment post licensure are cohort, case-control and self-controlled case series. These methods are often used with routine health databases and immunisation registries. This paper considers the issues that may arise when designing an epidemiological study, such as understanding the vaccine safety question, case definition and finding, limitations of data sources, uncontrolled confounding, and pitfalls that apply to the individual designs. The example of MMR and autism, where all three designs have been used, is presented to help consider these issues. PMID:21985898

  15. Grant-Writing Pearls and Pitfalls: Maximizing Funding Opportunities.

    PubMed

    Liu, Jeffrey C; Pynnonen, Melissa A; St John, Maie; Rosenthal, Eben L; Couch, Marion E; Schmalbach, Cecelia E

    2016-02-01

    This invited article reviews the grant process to include the following objectives: (1) to provide an understanding of otolaryngology funding mechanisms in the context of career progression; (2) to outline key components of a well-written grant; (3) to highlight vital members of a successful research team, with emphasis on the mentor-mentee relationship; and (4) to clarify grant scoring with emphasis on common pitfalls to avoid. Current otolaryngology funding mechanisms and up-to-date resources are provided. The review is aimed to assist otolaryngology residents, faculty new to the grant process, as well as experienced researchers striving to improve their grant review scores. PMID:26626133

  16. Scientific dishonesty and good scientific practice.

    PubMed

    Andersen, D; Axelsen, N H; Riis, P

    1993-04-01

    Scientific dishonesty has been the subject of much public interest in recent years. Although the problem has had a low profile in Denmark, there is no reason to believe that it is non-existent. Several preconditions known to be important prevail here as well as in other countries, such as pressure to publish and severe competition for research grants and senior academic positions. The Danish Medical Research Council (DMRC) decided to respond to this problem by preparing a report on scientific dishonesty with suggestions to the research institutions on rules for good scientific practice and procedures for investigation of suspected dishonesty. To this end, an investigatory system was suggested. The system should consist of two regional committees and one national committee. They should be headed by high court judges and experienced health sciences researchers as members. The committees will investigate cases reported to them and conclude on whether dishonesty has been established and on whether the scientific work should be retracted. Sanctions shall remain the task of the institutions. Preventive measures comprise open access to and a long storage period for scientific data. PMID:8495601

  17. Professional Scientific Blog

    ERIC Educational Resources Information Center

    Beke, Tamás

    2009-01-01

    The professional blog is a weblog that on the whole meets the requirements of scientific publication. In my opinion it bears a resemblance to digital notice boards, where the competent specialists of the given branch of science can place their ideas, questions, possible solutions and can raise problems. Its most important function can be…

  18. 50 CFR 600.512 - Scientific research.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... scientific research are requested to submit a copy of any cruise report or other publication created as a... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Scientific research. 600.512 Section 600... research. (a) Scientific research activity. Persons planning to conduct scientific research activities...

  19. 50 CFR 600.512 - Scientific research.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... scientific research are requested to submit a copy of any cruise report or other publication created as a... 50 Wildlife and Fisheries 10 2011-10-01 2011-10-01 false Scientific research. 600.512 Section 600... research. (a) Scientific research activity. Persons planning to conduct scientific research activities...

  20. Scientific Globish versus scientific English.

    PubMed

    Tychinin, Dmitry N; Kamnev, Alexander A

    2013-10-01

    The proposed adoption of 'scientific Globish' as a simplified language standard for scholarly communication may appeal to authors who have difficulty with English proficiency. However, Globish might not justify the hopes being pinned on it and might open the door to further deterioration of the quality of English-language scientific writing. PMID:23928006

  1. Estimation of the Publication Potential in 50 U.S. States and in the District of Columbia Based on the Frequency Distribution of Scientific Productivity.

    ERIC Educational Resources Information Center

    Schubert, Andras; Telcs, Andras

    1989-01-01

    Demonstrates the use of the Waring distribution as a model for the frequency distribution of scientific productivity. Methods for testing the fit at both ends of the distribution, as well as for estimating the parameters of the distribution and the total number of scientists, are outlined. (16 references) (Author/CLB)

  2. The Art of Scientific Writing: From Student Reports to Professional Publications in Chemistry and Related Fields. 2nd Completely Revised Edition

    ERIC Educational Resources Information Center

    Ebel, Hans F.; Bliefert, Claus; Russey, William E.

    2004-01-01

    Most scientists live in a "publish or perish" environment, but few would describe themselves as brilliant (or enthusiastic) writers. Coming to the aid of all those wishing to improve the quality of their scientific writing--established researchers and aspiring students alike--three experienced authors/scientists from differing backgrounds and…

  3. Investigation of the Public Library as a Linking Agent to Major Scientific, Educational, Social, and Environmental Data Bases. Sixth Progress Report, January 1976-March 1976.

    ERIC Educational Resources Information Center

    Summit, Roger K.; Firschein, Oscar

    In conjunction with the National Science Foundation (NSD), an on-going experiment is being conducted to test the feasibility of increasing public access to 16 major data bases by providing public libraries with on-line, interactive, retrieval capacity. During the period from January to March 1976, the major activities of the study were: (1) a…

  4. Investigation of the Public Library as a Linking Agent to Major Scientific, Educational, Social, and Environmental Data Bases. Two-Year Interim Report. Annex I: Evaluation Results.

    ERIC Educational Resources Information Center

    Ahlgren, Alice E.

    Four public libraries participated in a two-year investigation of the provision of on line reference services in a public library setting. To evaluate the utility and cost of the service, data were collected about search statistics, usage patterns, costs, and impact on the library. This volume of the report contains the evaluation methodology,…

  5. Human Rhabdomyosarcoma Cell Lines for Rhabdomyosarcoma Research: Utility and Pitfalls

    PubMed Central

    Hinson, Ashley R. P.; Jones, Rosanne; Crose, Lisa E. S.; Belyea, Brian C.; Barr, Frederic G.; Linardic, Corinne M.

    2013-01-01

    Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood and adolescence. Despite intergroup clinical trials conducted in Europe and North America, outcomes for high risk patients with this disease have not significantly improved in the last several decades, and survival of metastatic or relapsed disease remains extremely poor. Accrual into new clinical trials is slow and difficult, so in vitro cell-line research and in vivo xenograft models present an attractive alternative for preclinical research for this cancer type. Currently, 30 commonly used human RMS cell lines exist, with differing origins, karyotypes, histologies, and methods of validation. Selecting an appropriate cell line for RMS research has important implications for outcomes. There are also potential pitfalls in using certain cell lines including contamination with murine stromal cells, cross-contamination between cell lines, discordance between the cell line and its associated original tumor, imposter cell lines, and nomenclature errors that result in the circulation of two or more presumed unique cell lines that are actually from the same origin. These pitfalls can be avoided by testing for species-specific isoenzymes, microarray analysis, assays for subtype-specific fusion products, and short tandem repeat analysis. PMID:23882450

  6. Pitfalls and practicalities in collecting and banking human brain tissues for research on psychiatric and neulogical disorders.

    PubMed

    Ravid, Rivka; Ikemoto, Keiko

    2012-01-01

    It is essential to examine brain materials for the understanding the cause and pathology of mental disorders. Recent methodological progress urges us to set up well qualified brain banks. Human tissue and Bio-banking is a complex field and the daily practice of brain banks needs to abide by several golden standards in order to avoid pitfalls in basic research: 1) A donor system in which informed consent is granted for the use of the samples for scientific research, including genetic analysis and access to medical records, 2) Rapid autopsy system, 3) Compatibility of protocols for procurement, management, handling and storage, 4) A generally accepted consensus on diagnostic criteria, 5) Quality control, 6) Abiding by local/international legal and ethical guidelines for work with human material, 7) Proper safety procedures. In the present review, the authors introduced the activities of European brain banks, and discussed on their current issues, and on the problems remain to be resolved. PMID:22790897

  7. Scientific Misconduct.

    ERIC Educational Resources Information Center

    Goodstein, David

    2002-01-01

    Explores scientific fraud, asserting that while few scientists actually falsify results, the field has become so competitive that many are misbehaving in other ways; an example would be unreasonable criticism by anonymous peer reviewers. (EV)

  8. Pitfalls and limitations in translation from biomarker discovery to clinical utility in predictive and personalised medicine

    PubMed Central

    2013-01-01

    Since the emergence of the so-called omics technology, thousands of putative biomarkers have been identified and published, which have dramatically increased the opportunities for developing more effective therapeutics. These opportunities can have profound benefits for patients and for the economics of healthcare. However, the transfer of biomarkers from discovery to clinical practice is still a process filled with lots of pitfalls and limitations, mostly limited by structural and scientific factors. To become a clinically approved test, a potential biomarker should be confirmed and validated using hundreds of specimens and should be reproducible, specific and sensitive. Besides the lack of quality in biomarker validation, a number of other key issues can be identified and should be addressed. Therefore, the aim of this article is to discuss a series of interpretative and practical issues that need to be understood and resolved before potential biomarkers become a clinically approved test or are already on the diagnostic market. Some of these issues are shortly discussed here. PMID:23442211

  9. Symposium Scores Misuse of Scientific Data

    ERIC Educational Resources Information Center

    Krieger, James H.

    1975-01-01

    Presents examples of misuse of scientific data in the areas of eutrophication, food advertising, and public health. Outlines various ways in which individual scientists can act to ensure the proper use of scientific data. (GS)

  10. The Scientific Revolution: Paradigm Lost?

    ERIC Educational Resources Information Center

    Hatch, Robert A.

    1989-01-01

    Traces the historiography of the scientific revolution through a bibliographic essay. Examines trends in recent scholarly publications in an effort to identify new areas of research. Maintains that the study of the scientific revolution is problematic and cannot be reduced to simple analysis. (RW)

  11. Evolution of the scientific paper

    SciTech Connect

    Harmon, J.E.

    1992-01-01

    The first papers reporting original research results in technical periodicals and proceedings appeared in the late 17th century. Since that time, the typical scientific paper has evolved from a fairly simple document, accessible to a general audience, to a much more complex one, aimed at a specialized audience. The purpose of this article is to give an overview of what the first scientific papers were like and how they evolved to their present form and style. To facilitate this discussion, the scientific paper's development has arbitrarily been divided into four stages: the origin and formative years of the scientific paper (1665-1765), emergence of scientific papers written for specialized publications (1765-1865), development of the modem scientific paper (1865-1965), and hyperspecialization and computerization of the modem scientific paper (1965- ).

  12. Evolution of the scientific paper

    SciTech Connect

    Harmon, J.E.

    1992-09-01

    The first papers reporting original research results in technical periodicals and proceedings appeared in the late 17th century. Since that time, the typical scientific paper has evolved from a fairly simple document, accessible to a general audience, to a much more complex one, aimed at a specialized audience. The purpose of this article is to give an overview of what the first scientific papers were like and how they evolved to their present form and style. To facilitate this discussion, the scientific paper`s development has arbitrarily been divided into four stages: the origin and formative years of the scientific paper (1665-1765), emergence of scientific papers written for specialized publications (1765-1865), development of the modem scientific paper (1865-1965), and hyperspecialization and computerization of the modem scientific paper (1965-?).

  13. NASA educational publications

    NASA Technical Reports Server (NTRS)

    1987-01-01

    This is a catalog of educational and technical publications, sponsored by NASA, that are available to the general public from the Government Printing Office (GPO). The following types of publications are announced: periodicals, educational publications, NASA Facts, posters and wallsheets, other publications of interest to educators, scientific and technical publications, and educational materials from Regional Service Centers.

  14. Scientific millenarianism

    SciTech Connect

    Weinberg, A.M.

    1997-12-01

    Today, for the first time, scientific concerns are seriously being addressed that span future times--hundreds, even thousands, or more years in the future. One is witnessing what the author calls scientific millenarianism. Are such concerns for the distant future exercises in futility, or are they real issues that, to the everlasting gratitude of future generations, this generation has identified, warned about and even suggested how to cope with in the distant future? Can the four potential catastrophes--bolide impact, CO{sub 2} warming, radioactive wastes and thermonuclear war--be avoided by technical fixes, institutional responses, religion, or by doing nothing? These are the questions addressed in this paper.

  15. Public health assessment for Scientific Chemical Processing Incorporated, Carlstadt, Bergen County, New Jersey, Region 2. CERCLIS No. NJD070565403. Final report

    SciTech Connect

    Not Available

    1993-11-16

    The Scientific Chemical Processing (SCP) site is located in Carlstadt Borough, Bergen County, New Jersey. A wide variety of organic and inorganic chemical contaminants (volatiles, acid extractables, base/neutrals, pesticides, polychlorinated biphenyls, phenolics, cyanides and petroleum hydrocarbons and metals) were found in site soils and ground water, and in surface water and sediments in the vicinity of the site. The extent and degree of contamination is most severe in the site soils and shallow ground water. Potential human exposure pathways existed prior to the completion of the Interim remedy (June 1992). The site is not being considered for follow-up health activities at this time.

  16. Mastering methodological pitfalls for surviving the metagenomic jungle.

    PubMed

    Delmont, Tom O; Simonet, Pascal; Vogel, Timothy M

    2013-08-01

    Metagenomics is a culture- and PCR-independent approach that is now widely exploited for directly studying microbial evolution, microbial ecology, and developing biotechnologies. Observations and discoveries are critically dependent on DNA extraction methods, sequencing technologies, and bioinformatics tools. The potential pitfalls need to be understood and, to some degree, mastered if the resulting data are to survive scrutiny. In particular, methodological variations appear to affect results from different ecosystems differently, thus increasing the risk of biological and ecological misinterpretation. Part of the difficulty is derived from the lack of knowledge concerning the true microbial diversity and because no approach can guarantee accessing microorganisms in the same proportion in which they exist in the environment. However, the variation between different approaches (e.g. DNA extraction techniques, sequence annotation systems) can be used to evaluate whether observations are meaningful. These methodological variations can be integrated into the error analysis before comparing microbial communities. PMID:23757040

  17. Individual therapy for couple problems: perspectives and pitfalls.

    PubMed

    Gurman, Alan S; Burton, Mark

    2014-10-01

    Despite the demonstrated efficacy of conjoint couple therapy, many clients seeking help for couple problems ultimately find themselves in individual therapy for these concerns. Individual therapy for couple problems (ITCP) may evolve from a partner's refusal of conjoint therapy or from the treatment format preferences of either the client or therapist. Having acknowledged the role of partner refusals, we offer some perspectives about the idiosyncratic personal factors and professional background factors that may lead therapists to provide ITCP and discuss the significant pitfalls in its practice. We emphasize five central areas of concern in the ongoing practice of ITCP: structural constraints on change; therapist side-taking and the therapeutic alliance; inaccurate assessments based on individual client reports; therapeutic focus; and ethical issues relevant to both attending and nonattending partners. We conclude by urging that this very important but largely neglected topic be paid greater attention in psychotherapy research, training and continuing education. PMID:24773422

  18. The Head-fixed Behaving Rat—Procedures and Pitfalls

    PubMed Central

    Schwarz, Cornelius; Hentschke, Harald; Butovas, Sergejus; Haiss, Florent; Stüttgen, Maik C; Gerdjikov, Todor V; Bergner, Caroline G; Waiblinger, Christian

    2010-01-01

    This paper describes experimental techniques with head-fixed, operantly conditioned rodents that allow the control of stimulus presentation and tracking of motor output at hitherto unprecedented levels of spatio-temporal precision. Experimental procedures for the surgery and behavioral training are presented. We place particular emphasis on potential pitfalls using these procedures in order to assist investigators who intend to engage in this type of experiment. We argue that head-fixed rodent models, by allowing the combination of methodologies from molecular manipulations, intracellular electrophysiology, and imaging to behavioral measurements, will be instrumental in combining insights into the functional neuronal organization at different levels of observation. Provided viable behavioral methods are implemented, model systems based on rodents will be complementary to current primate models—the latter providing highest comparability with the human brain, while the former offer hugely advanced methodologies on the lower levels of organization, for example, genetic alterations, intracellular electrophysiology, and imaging. PMID:20954892

  19. Chemometrics applied to vibrational spectroscopy: overview, challenges and pitfalls

    SciTech Connect

    Haaland, D.M.

    1996-10-01

    Chemometric multivariate calibration methods are rapidly impacting quantitative infrared spectroscopy in many positive ways. The combination of vibrational spectroscopy and chemometrics has been used by industry for quality control and process monitoring. The growth of these methods has been phenomenal in the past decade. Yet, as with any new technology, there are growing pains. The methods are so powerful at finding correlations in the data, that when used without great care they can readily yield results that are not valid for the analysis of future unknown samples. In this paper, the power of the multivariate calibration methods is discussed while pointing out common pitfalls and some remaining challenges that may slow the implementation of chemometrics in research and industry.

  20. Surgery for Locally Recurrent Rectal Cancer: Tips, Tricks, and Pitfalls.

    PubMed

    Warrier, Satish K; Heriot, Alexander G; Lynch, Andrew Craig

    2016-06-01

    Rectal cancer can recur locally in up to 10% of the patients who undergo definitive resection for their primary cancer. Surgical salvage is considered appropriate in the curative setting as well as select cases with palliative intent. Disease-free survival following salvage resection is dependent upon achieving an R0 resection margin. A clear understanding of applied surgical anatomy, appropriate preoperative planning, and a multidisciplinary approach to aggressive soft tissue, bony, and vascular resection with appropriate reconstruction is necessary. Technical tips, tricks, and pitfalls that may assist in managing these cancers are discussed and the roles of additional boost radiation and intraoperative radiation therapy in the management of such cancers are also discussed. PMID:27247536

  1. Disseminated adenovirus infection in an immunocompromised host. Pitfalls in diagnosis.

    PubMed

    Landry, M L; Fong, C K; Neddermann, K; Solomon, L; Hsiung, G D

    1987-09-01

    In this report, a bone marrow transplant recipient with rapidly fatal gastroenteritis is presented. The presence of intranuclear inclusions on postmortem light microscopic examination of liver, lung, and small bowel tissue was considered diagnostic of cytomegalovirus infection. However, electron microscopic examination of liver tissue demonstrated adenovirus infection. This was confirmed by isolation of an adenovirus type 2 with unusual laboratory features from liver, lung, colon contents, serum, esophageal swab, and oral ulcerations. Results of a complement fixation test for antibodies to adenovirus performed on postmortem serum samples were negative, and a titer of 1:4 was noted for antibody against cytomegalovirus. This case illustrates the diagnostic pitfalls that may be encountered in establishing a specific viral diagnosis in severely ill patients. PMID:2821806

  2. The neuroaesthetics of prose fiction: pitfalls, parameters and prospects.

    PubMed

    Burke, Michael

    2015-01-01

    There is a paucity of neuroaesthetic studies on prose fiction. This is in contrast to the very many impressive studies that have been conducted in recent times on the neuroaesthetics of sister arts such as painting, music and dance. Why might this be the case, what are its causes and, of greatest importance, how can it best be resolved? In this article, the pitfalls, parameters and prospects of a neuroaesthetics of prose fiction will be explored. The article itself is part critical review, part methodological proposal and part opinion paper. Its aim is simple: to stimulate, excite and energize thinking in the discipline as to how prose fiction might be fully integrated in the canon of neuroaesthetics and to point to opportunities where neuroimaging studies on literary discourse processing might be conducted in collaborative work bringing humanists and scientists together. PMID:26283953

  3. Potential pitfalls of strain rate imaging: angle dependency

    NASA Technical Reports Server (NTRS)

    Castro, P. L.; Greenberg, N. L.; Drinko, J.; Garcia, M. J.; Thomas, J. D.

    2000-01-01

    Strain Rate Imaging (SRI) is a new echocardiographic technique that allows for the real-time determination of myocardial SR, which may be used for the early and accurate detection of coronary artery disease. We sought to study whether SR is affected by scan line alignment in a computer simulation and an in vivo experiment. Through the computer simulation and the in vivo experiment we generated and validated safe scanning sectors within the ultrasound scan sector and showed that while SRI will be an extremely valuable tool in detecting coronary artery disease there are potential pitfalls for the unwary clinician. Only after accounting for these affects due to angle dependency, can clinicians utilize SRI's potential as a valuable tool in detecting coronary artery disease.

  4. The neuroaesthetics of prose fiction: pitfalls, parameters and prospects

    PubMed Central

    Burke, Michael

    2015-01-01

    There is a paucity of neuroaesthetic studies on prose fiction. This is in contrast to the very many impressive studies that have been conducted in recent times on the neuroaesthetics of sister arts such as painting, music and dance. Why might this be the case, what are its causes and, of greatest importance, how can it best be resolved? In this article, the pitfalls, parameters and prospects of a neuroaesthetics of prose fiction will be explored. The article itself is part critical review, part methodological proposal and part opinion paper. Its aim is simple: to stimulate, excite and energize thinking in the discipline as to how prose fiction might be fully integrated in the canon of neuroaesthetics and to point to opportunities where neuroimaging studies on literary discourse processing might be conducted in collaborative work bringing humanists and scientists together. PMID:26283953

  5. Merits and Pitfalls of Currently Used Diagnostic Tools in Mycetoma

    PubMed Central

    van de Sande, Wendy W. J.; Fahal, Ahmed H.; Goodfellow, Michael; Mahgoub, El Sheikh; Welsh, Oliverio; Zijlstra, Ed E.

    2014-01-01

    Treatment of mycetoma depends on the causative organism and since many organisms, both actinomycetes (actinomycetoma) and fungi (eumycetoma), are capable of producing mycetoma, an accurate diagnosis is crucial. Currently, multiple diagnostic tools are used to determine the extent of infections and to identify the causative agents of mycetoma. These include various imaging, cytological, histopathological, serological, and culture techniques; phenotypic characterisation; and molecular diagnostics. In this review, we summarize these techniques and identify their merits and pitfalls in the identification of the causative agents of mycetoma and the extent of the disease. We also emphasize the fact that there is no ideal diagnostic tool available to identify the causative agents and that future research should focus on the development of new and reliable diagnostic tools. PMID:24992636

  6. Multi-criteria decision analysis: Limitations, pitfalls, and practical difficulties

    SciTech Connect

    Kujawski, Edouard

    2003-02-01

    The 2002 Winter Olympics women's figure skating competition is used as a case study to illustrate some of the limitations, pitfalls, and practical difficulties of Multi-Criteria Decision Analysis (MCDA). The paper compares several widely used models for synthesizing the multiple attributes into a single aggregate value. The various MCDA models can provide conflicting rankings of the alternatives for a common set of information even under states of certainty. Analysts involved in MCDA need to deal with the following challenging tasks: (1) selecting an appropriate analysis method, and (2) properly interpreting the results. An additional trap is the availability of software tools that implement specific MCDA models that can beguile the user with quantitative scores. These conclusions are independent of the decision domain and they should help foster better MCDA practices in many fields including systems engineering trade studies.

  7. Scrum and Global Delivery: Pitfalls and Lessons Learned

    NASA Astrophysics Data System (ADS)

    Sadun, Cristiano

    Two trends are becoming widespread in software development work—agile development processes and global delivery, both promising sizable benefits in productivity, capacity and so on. Combining the two is a highly attractive possibility, even more so in fast-paced and constrained commercial software engineering projects. However, a degree of conflict exists between the assumptions underlying the two ideas, leading to pitfalls and challenges in agile/distributed projects which are new, both with respect to traditional development and agile or distributed efforts adopted separately. Succeeding in commercial agile/distributed projects implies recognizing these new challenges, proactively planning for them, and actively put in place solutions and methods to overcome them. This chapter illustrates some of the typical challenges that were met during real-world commercial projects, and how they were solved.

  8. Extrapolation technique pitfalls in asymmetry measurements at colliders

    NASA Astrophysics Data System (ADS)

    Colletti, Katrina; Hong, Ziqing; Toback, David; Wilson, Jonathan S.

    2016-09-01

    Asymmetry measurements are common in collider experiments and can sensitively probe particle properties. Typically, data can only be measured in a finite region covered by the detector, so an extrapolation from the visible asymmetry to the inclusive asymmetry is necessary. Often a constant multiplicative factor is advantageous for the extrapolation and this factor can be readily determined using simulation methods. However, there is a potential, avoidable pitfall involved in the determination of this factor when the asymmetry in the simulated data sample is small. We find that to obtain a reliable estimate of the extrapolation factor, the number of simulated events required rises as the inverse square of the simulated asymmetry; this can mean that an unexpectedly large sample size is required when determining the extrapolation factor.

  9. Avoiding the pitfalls of adaptive management implementation in Swedish silviculture.

    PubMed

    Rist, Lucy; Felton, Adam; Mårald, Erland; Samuelsson, Lars; Lundmark, Tomas; Rosvall, Ola

    2016-02-01

    There is a growing demand for alternatives to Sweden's current dominant silvicultural system, driven by a desire to raise biomass production, meet environmental goals and mitigate climate change. However, moving towards diversified forest management that deviates from well established silvicultural practices carries many uncertainties and risks. Adaptive management is often suggested as an effective means of managing in the context of such complexities. Yet there has been scepticism over its appropriateness in cases characterised by large spatial extents, extended temporal scales and complex land ownership-characteristics typical of Swedish forestry. Drawing on published research, including a new paradigm for adaptive management, we indicate how common pitfalls can be avoided during implementation. We indicate the investment, infrastructure, and considerations necessary to benefit from adaptive management. In doing so, we show how this approach could offer a pragmatic operational model for managing the uncertainties, risks and obstacles associated with new silvicultural systems and the challenges facing Swedish forestry. PMID:26744049

  10. Clinical and Biochemical Pitfalls in the Diagnosis of Peroxisomal Disorders.

    PubMed

    Klouwer, Femke C C; Huffnagel, Irene C; Ferdinandusse, Sacha; Waterham, Hans R; Wanders, Ronald J A; Engelen, Marc; Poll-The, Bwee Tien

    2016-08-01

    Peroxisomal disorders are a heterogeneous group of genetic metabolic disorders, caused by a defect in peroxisome biogenesis or a deficiency of a single peroxisomal enzyme. The peroxisomal disorders include the Zellweger spectrum disorders, the rhizomelic chondrodysplasia punctata spectrum disorders, X-linked adrenoleukodystrophy, and multiple single enzyme deficiencies. There are several core phenotypes caused by peroxisomal dysfunction that clinicians can recognize. The diagnosis is suggested by biochemical testing in blood and urine and confirmed by functional assays in cultured skin fibroblasts, followed by mutation analysis. This review describes the phenotype of the main peroxisomal disorders and possible pitfalls in (laboratory) diagnosis to aid clinicians in the recognition of this group of diseases. PMID:27089543

  11. Hyperpolarized Renal Magnetic Resonance Imaging: Potential and Pitfalls.

    PubMed

    Laustsen, Christoffer

    2016-01-01

    The introduction of dissolution dynamic nuclear polarization (d-DNP) technology has enabled a new paradigm for renal imaging investigations. It allows standard magnetic resonance imaging complementary renal metabolic and functional fingerprints within seconds without the use of ionizing radiation. Increasing evidence supports its utility in preclinical research in which the real-time interrogation of metabolic turnover can aid the physiological and pathophysiological metabolic and functional effects in ex vivo and in vivo models. The method has already been translated to humans, although the clinical value of this technology is unknown. In this paper, I review the potential benefits and pitfalls associated with dissolution dynamic nuclear polarization in preclinical research and its translation to renal patients. PMID:26973539

  12. Hyperpolarized Renal Magnetic Resonance Imaging: Potential and Pitfalls

    PubMed Central

    Laustsen, Christoffer

    2016-01-01

    The introduction of dissolution dynamic nuclear polarization (d-DNP) technology has enabled a new paradigm for renal imaging investigations. It allows standard magnetic resonance imaging complementary renal metabolic and functional fingerprints within seconds without the use of ionizing radiation. Increasing evidence supports its utility in preclinical research in which the real-time interrogation of metabolic turnover can aid the physiological and pathophysiological metabolic and functional effects in ex vivo and in vivo models. The method has already been translated to humans, although the clinical value of this technology is unknown. In this paper, I review the potential benefits and pitfalls associated with dissolution dynamic nuclear polarization in preclinical research and its translation to renal patients. PMID:26973539

  13. Clinical pitfalls in diagnosis of nonmuscle-invasive bladder cancer.

    PubMed

    Serretta, Vincenzo; Scalici Gesolfo, Cristina

    2015-10-01

    Current global economic crisis imposes healthcare system to reduce unnecessary investigations and increase early detection of tumors, to decrease the costs of an advanced disease. Several diagnostic pitfalls may occur dealing with bladder cancer (BC), particularly in nonmuscle-invasive (NMIBC) one. Hematuria, the commonest sign in NMIBC, is often underestimated. Urinary cytology is highly specific for high-grade tumors, but has a low sensitivity for low-grade BC, is operator dependent, and not always obtainable in clinical practice. Numerous urinary tests are available to ameliorate the accuracy of cytology, but none of them is routinly used in urological practice. Ultrasound could hardly detect a small bladder tumor, especially if located in the bladder neck or in the anterior wall. Computed tomography (CT) is widely adopted as an alternative to conventional urography, but its usefulness in patients with hematuria is still debated. MRI has a higher accuracy than CT for staging BC and evaluate the bladder-wall invasion. A negative cystoscopy cannot exclude Tis and should be accompanied by urinary cytology in patients with suspected Tis or high-risk NMIBC; however, new techniques such as narrow band imaging (NBI) and photodynamic (PDD) increase the detection rate of BC and flat lesions. Nearly half of all diagnostic resections present omission of muscle in the specimen or its mention in the pathology report, which is associated with an increased mortality. An adequate muscle sampling during endoscopic resection is mandatory, particularly in patients with high-grade disease. Recognition of pitfalls in diagnosis and management of BC represents the first step for a correct approach. PMID:26481718

  14. NASA's Scientific Visualization Studio

    NASA Technical Reports Server (NTRS)

    Mitchell, Horace G.

    2003-01-01

    Since 1988, the Scientific Visualization Studio(SVS) at NASA Goddard Space Flight Center has produced scientific visualizations of NASA s scientific research and remote sensing data for public outreach. These visualizations take the form of images, animations, and end-to-end systems and have been used in many venues: from the network news to science programs such as NOVA, from museum exhibits at the Smithsonian to White House briefings. This presentation will give an overview of the major activities and accomplishments of the SVS, and some of the most interesting projects and systems developed at the SVS will be described. Particular emphasis will be given to the practices and procedures by which the SVS creates visualizations, from the hardware and software used to the structures and collaborations by which products are designed, developed, and delivered to customers. The web-based archival and delivery system for SVS visualizations at svs.gsfc.nasa.gov will also be described.

  15. Making better scientific figures

    NASA Astrophysics Data System (ADS)

    Hawkins, Ed; McNeall, Doug

    2016-04-01

    In the words of the UK government chief scientific adviser "Science is not finished until it's communicated" (Walport 2013). The tools to produce good visual communication have never been so easily accessible to scientists as at the present. Correspondingly, it has never been easier to produce and disseminate poor graphics. In this presentation, we highlight some good practice and offer some practical advice in preparing scientific figures for presentation to peers or to the public. We identify common mistakes in visualisation, including some made by the authors, and offer some good reasons not to trust defaults in graphics software. In particular, we discuss the use of colour scales and share our experiences in running a social media campaign (http://tiny.cc/endrainbow) to replace the "rainbow" (also "jet", or "spectral") colour scale as the default in (climate) scientific visualisation.

  16. Scientific Documentation.

    ERIC Educational Resources Information Center

    Pieper, Gail W.

    1980-01-01

    Describes how scientific documentation is taught in three 50-minute sessions in a technical writing course. Tells how session one distinguishes between in-text notes, footnotes, and reference entries; session two discusses the author-year system of citing references; and session three is concerned with the author-number system of reference…

  17. Scientific Inquiry

    ERIC Educational Resources Information Center

    National Science Teachers Association (NJ1), 2004

    2004-01-01

    Scientific inquiry reflects how scientists come to understand the natural world, and it is at the heart of how students learn. From a very early age, children interact with their environment, ask questions, and seek ways to answer those questions. Understanding science content is significantly enhanced when ideas are anchored to inquiry…

  18. Scientific basis of the national ambient air quality standards for ozone: How do new discoveries and other concerns modify public health risks and expected benefits?

    SciTech Connect

    Vostal, J.J.; Heuss, J.M.; Paul, R.T.; Pezda, S.A.; Ball, J.C.; Wimette, H.J.

    1999-07-01

    The US EPA, in their recent review of the ozone NAAQS, acknowledged that substantial uncertainties exist with respect to the determination of public health risks due to ambient ozone. In particular, the uncertainties focus on considerable differences of opinion among scientists for the possible health effects at ozone levels near the new 8-hr. ozone National Air Quality Standard (NAAQS) of 0.08 ppm. Information on health or vegetation effects of low ambient ozone levels has been scarce, or extrapolated from studies using levels that are substantially above the new standard level. Uncertainties fall into three categories: (1) the extent of the adversity of public health endpoints; (2) the probability of adverse exposures; and (3) the impact of background levels on the achievability of the new standard. More specifically: (A) Public health effects of low ozone levels have thus far depended primarily on compromised pulmonary function as the biological endpoint of the greatest clinical significance. However, research data published after the standard was promulgated show that the ozone-induced effects represent more a physiological defense mechanism than an adverse effect of low ambient ozone concentrations. In light of these new findings, the alleged ozone action represents only a decline in pulmonary function test performance and not in the vital function of the lungs. This new interpretation not only eliminates the adverse character of pulmonary function decrements, but also largely modifies the proposed estimates of public health risks. (B) Public health risk assessments have indicated that even with compliance of the 1-hour ozone standard, the chances for US populations to encounter an adverse ozone exposure have been practically eliminated.

  19. Pitfalls in Persuasion: How Do Users Experience Persuasive Techniques in a Web Service?

    NASA Astrophysics Data System (ADS)

    Segerståhl, Katarina; Kotro, Tanja; Väänänen-Vainio-Mattila, Kaisa

    Persuasive technologies are designed by utilizing a variety of interactive techniques that are believed to promote target behaviors. This paper describes a field study in which the aim was to discover possible pitfalls of persuasion, i.e., situations in which persuasive techniques do not function as expected. The study investigated persuasive functionality of a web service targeting weight loss. A qualitative online questionnaire was distributed through the web service and a total of 291 responses were extracted for interpretative analysis. The Persuasive Systems Design model (PSD) was used for supporting systematic analysis of persuasive functionality. Pitfalls were identified through situations that evoked negative user experiences. The primary pitfalls discovered were associated with manual logging of eating and exercise behaviors, appropriateness of suggestions and source credibility issues related to social facilitation. These pitfalls, when recognized, can be addressed in design by applying functional and facilitative persuasive techniques in meaningful combinations.

  20. Missed Opportunities in the Patient-Focused Drug Development Public Meeting and Scientific Workshop on Female Sexual Dysfunction Held at the FDA, October 2014.

    PubMed

    Tiefer, Leonore; Laan, Ellen; Basson, Rosemary

    2015-01-01

    There were numerous missed opportunities at the October 2014 U.S. Food and Drug Administration (FDA) meeting on female sexual dysfunction (FSD). They included opportunities to hear from a diverse range of patients and to engage in evidence-based discussions of unmet medical needs, diagnostic instruments, trial end points, and inclusion criteria for clinical trials. Contributions of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) nomenclature, based on extensive research, were dismissed in favor of language favoring a seemingly clear but scientifically unsupportable distinction between women's sexual desire and arousal. Numerous participants, including patients recruited by their physicians, acknowledged travel expenses paid for by interested pharmaceutical companies. Conflicts of interest were manifold. The meeting did not advance the FDA's understanding of women's sexual distress and represents a setback for our field. PMID:26010838

  1. Musculoskeletal pitfalls and pseudotumours in the pelvis: a pictorial review for body imagers

    PubMed Central

    Ghazizadeh, S; Didier, R; Fung, A; Panicek, D M; Coakley, F V

    2014-01-01

    Many musculoskeletal abnormalities in the pelvis are first seen by body imagers while reviewing pelvic cross-sectional studies, and some of these abnormalities may mimic malignancy or another aggressive process. This article describes nine musculoskeletal pseudotumours and interpretative pitfalls that may be seen on CT, MRI and ultrasound imaging of the pelvis. Awareness of these pitfalls and pseudotumours may help avoid misdiagnosis and prevent inappropriate intervention or management. PMID:25096891

  2. Scientific Claims versus Scientific Knowledge.

    ERIC Educational Resources Information Center

    Ramsey, John

    1991-01-01

    Provides activities that help students to understand the importance of the scientific method. The activities include the science of fusion and cold fusion; a group activity that analyzes and interprets the events surrounding cold fusion; and an application research project concerning a current science issue. (ZWH)

  3. [Trichinae, pigs and veterinary public health: The introduction of the microscopic world into the scientific basis for meat inspection (Barcelona, 1870s)].

    PubMed

    Gutiérrez García, José Manuel

    2016-01-01

    During the second half of the 19th century, Spanish authorities began developing specific programs on the safety of certain foods intended for human consumption. This paper analyses the key features that gave rise to the inclusion of the veterinarian in the administrative structure responsible for safeguarding public health. Among the aspects covered, special focus is put on the relationship between human and animal medicine at a time when growing public alarm in relation to certain zoonoses contributed to shaping the notion of veterinary public health. The appearance of a disease in pigs that was transmissible through the consumption of parasitized meat set the scene for veterinary inspection to be associated with the protection of public health. The outbreaks of trichinosis all over Spain in the 1870's proved the existence of contagium animatum in a pre-bacteriology era, and this led to the introduction of improvements in food inspection. In this sense, microscopic examination of pork products encouraged the modernization of inspection tasks undertaken by veterinarians, which had previously focused on the organoleptic evaluation of meat and fish and on unveiling fraud. The introduction of microscopes was widely accepted and established a watershed between acceptable and unacceptable methods of carrying out the examination of meat. Furthermore, this "technological" method of diagnosis brought veterinary medicine closer to other more prestigious health professions, at least in theory. Among other aspects, the acceptance of trichinae as an exogenous cause of disease contributed to 19th century doctors learning about the idea of pathogenic microorganisms from veterinarians. At a social level, the use of the microscope was seen as a way of preventing the transmission to people of an animal disease that was very much in the public eye at the time. From the political point of view, the process -analysed in this paper from the perspective of veterinarians in Barcelona

  4. Scientific Misconduct

    NASA Astrophysics Data System (ADS)

    Moore, John W.

    2002-12-01

    These cases provide a good basis for discussions of scientific ethics, particularly with respect to the responsibilities of colleagues in collaborative projects. With increasing numbers of students working in cooperative or collaborative groups, there may be opportunities for more than just discussion—similar issues of responsibility apply to the members of such groups. Further, this is an area where, “no clear, widely accepted standards of behavior exist” (1). Thus there is an opportunity to point out to students that scientific ethics, like science itself, is incomplete and needs constant attention to issues that result from new paradigms such as collaborative research. Finally, each of us can resolve to pay more attention to the contributions we and our colleagues make to collaborative projects, applying to our own work no less critical an eye than we would cast on the work of those we don’t know at all.

  5. The pitfalls of field trials in fish vaccinology.

    PubMed

    Mitchell, H

    1997-01-01

    Field trials are essential for accurately assessing the worth of a vaccine under actual conditions of use. Compared with the laboratory, the dynamics of the host, pathogen, and environment in a production setting can produce both subtle and dramatic differences on the performance of the vaccine and the immune response. Because of this, field trials are conducted by manufacturers in vaccine development and are required by many national regulatory agencies to evaluate safety and/or efficacy before granting vaccine licenses. Aquaculture producers, veterinarians and fish health professionals can use field trials to analyse the cost-benefit of a vaccination programme for a facility, or to compare competitive products. Vaccine field trials are more than merely using the products in the field. Small efficacy effects can result in considerable cost reductions to the fish farmer. Proper field trial design, conduct and analysis is critical to detecting these effects. However, field trials are also fraught with many pitfalls that can result in failure or misleading conclusions. The discussion regarding possible pitfalls of vaccine field trials in aquaculture is divided into two parts: 1) the art and 2) the science of successful field trials. The art of successful field trials involves dealing with the "people" aspect which is necessary for initial and continuing compliance. Meticulous planning is essential, including a written protocol to which everyone agrees by signature. The bottom line to the art of field trials is anticipation and discussion of all possible eventualities together with constant communication with the farmer and site supervisor. The science of successful fields trials involves anticipating and realizing the logistical and statistical difficulties in design and implementation. Problems often encountered are: lack of stated quantifiable purpose; low power of the test due to inherent small sample size, large variation and small margin of effect; lack of

  6. Ethics and Pragmatism in Scientific Affairs.

    ERIC Educational Resources Information Center

    Ryan, Kenneth J.

    1979-01-01

    While the public, including many scientists, have grave anxieties about the consequences of such technical achievements as recombinant DNA, challenges to the extent of freedom of scientific inquiry must be critically examined. However, scientific freedom cannot be used to justify blanket immunity from legitimate governmental and public oversight.…

  7. 76 FR 36094 - Draft NOAA Scientific Integrity Policy and Handbook; Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-21

    ... National Oceanic and Atmospheric Administration Draft NOAA Scientific Integrity Policy and Handbook... Administration (NOAA), Department of Commerce (DOC). ACTION: Draft NOAA Scientific Integrity Policy and Handbook for Public Review. SUMMARY: NOAA's draft scientific integrity policy is available for public...

  8. Bed bug (Heteroptera: Cimicidae) attraction to pitfall traps baited with carbon dioxide, heat, and chemical lure.

    PubMed

    Wang, Changlu; Gibb, Timothy; Bennett, Gary W; McKnight, Susan

    2009-08-01

    Carbon dioxide (CO2), heat, and chemical lure (1-octen-3-ol and L-lactic acid) were tested as attractants for bed bugs, Cimex lectularius L. (Heteroptera: Cimicidae), by using pitfall traps. Both CO2 and heat were attractive to bed bugs. CO2 was significantly more attractive to bed bugs than heat. Traps baited with chemical lure attracted more bed bugs but at a statistically nonsignificant level. In small arena studies (56 by 44 cm), pitfall traps baited with CO2 or heat trapped 79.8 +/- 6.7 and 51.6 +/- 0.9% (mean +/- SEM) of the bed bugs after 6 h, respectively. Traps baited with CO2 + heat, CO, + chemical lure, or CO2 + heat + chemical lure captured > or = 86.7% of the bed bugs after 6 h, indicating baited pitfall traps were highly effective in attracting and capturing bed bugs from a short distance. In 3.1- by 1.8-m environmental chambers, a pitfall trap baited with CO, + heat + chemical lure trapped 57.3 +/- 6.4% of the bed bugs overnight. The pitfall trap was further tested in four bed bug-infested apartments to determine its efficacy in detecting light bed bug infestations. Visual inspections found an average of 12.0 +/- 5.4 bed bugs per apartment. The bed bugs that were found by visual inspections were hand-removed during inspections. A pitfall trap baited with CO2 and chemical lure was subsequently placed in each apartment with an average of 15.0 +/- 6.4 bed bugs collected per trap by the next morning. We conclude that baited pitfall traps are potentially effective tools for evaluating bed bug control programs and detecting early bed bug infestations. PMID:19736771

  9. EPA scientific integrity policy draft

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2011-08-01

    The U.S. Environmental Protection Agency (EPA) issued its draft scientific integrity policy on 5 August. The draft policy addresses scientific ethical standards, communications with the public, the use of advisory committees and peer review, and professional development. The draft policy was developed by an ad hoc group of EPA senior staff and scientists in response to a December 2010 memorandum on scientific integrity from the White House Office of Science and Technology Policy. The agency is accepting public comments on the draft through 6 September; comments should be sent to osa.staff@epa.gov. For more information, see http://www.epa.gov/stpc/pdfs/draft-scientific-integrity-policy-aug2011.pdf.

  10. Cannulation Strategies and Pitfalls in Minimally Invasive Cardiac Surgery

    PubMed Central

    Ramchandani, Mahesh; Al Jabbari, Odeaa; Abu Saleh, Walid K.; Ramlawi, Basel

    2016-01-01

    For any given cardiac surgery, there are two invasive components: the surgical approach and the cardiopulmonary bypass circuit. The standard approach for cardiac surgery is the median sternotomy, which offers unrestricted access to the thoracic organs—the heart, lung, and major vessels. However, it carries a long list of potential complications such as wound infection, brachial plexus palsies, respiratory dysfunction, and an unpleasant-looking scar. The cardiopulmonary bypass component also carries potential complications such as end-organ dysfunction, coagulopathy, hemodilution, bleeding, and blood transfusion requirement. Furthermore, the aortic manipulation during cannulation and cross clamping increases the risk of dissection, arterial embolization, and stroke. Minimally invasive cardiac surgery is an iconic event in the history of cardiothoracic medicine and has become a widely adapted approach as it minimizes many of the inconvenient side effects associated with the median sternotomy and bypass circuit placement. This type of surgery requires the use of novel perfusion strategies, especially in patients who hold the highest potential for postoperative morbidity. Cannulation techniques are a fundamental element in minimally invasive cardiac surgery, and there are numerous cannulation procedures for each type of minimally invasive operation. In this review, we will highlight the strategies and pitfalls associated with a minimally invasive cannulation. PMID:27127556

  11. Magnetic resonance thermometry: Methodology, pitfalls and practical solutions.

    PubMed

    Winter, Lukas; Oberacker, Eva; Paul, Katharina; Ji, Yiyi; Oezerdem, Celal; Ghadjar, Pirus; Thieme, Alexander; Budach, Volker; Wust, Peter; Niendorf, Thoralf

    2016-01-01

    Clinically established thermal therapies such as thermoablative approaches or adjuvant hyperthermia treatment rely on accurate thermal dose information for the evaluation and adaptation of the thermal therapy. Intratumoural temperature measurements have been correlated successfully with clinical end points. Magnetic resonance imaging is the most suitable technique for non-invasive thermometry avoiding complications related to invasive temperature measurements. Since the advent of MR thermometry two decades ago, numerous MR thermometry techniques have been developed, continuously increasing accuracy and robustness for in vivo applications. While this progress was primarily focused on relative temperature mapping, current and future efforts will likely close the gap towards quantitative temperature readings. These efforts are essential to benchmark thermal therapy efficiency, to understand temperature-related biophysical and physiological processes and to use these insights to set new landmarks for diagnostic and therapeutic applications. With that in mind, this review summarises and discusses advances in MR thermometry, providing practical considerations, pitfalls and technical obstacles constraining temperature measurement accuracy, spatial and temporal resolution in vivo. Established approaches and current trends in thermal therapy hardware are surveyed with respect to potential benefits for MR thermometry. PMID:26708630

  12. Pitfalls in the measurement and interpretation of thyroid function tests.

    PubMed

    Koulouri, Olympia; Moran, Carla; Halsall, David; Chatterjee, Krishna; Gurnell, Mark

    2013-12-01

    Thyroid function tests (TFTs) are amongst the most commonly requested laboratory investigations in both primary and secondary care. Fortunately, most TFTs are straightforward to interpret and confirm the clinical impression of euthyroidism, hypothyroidism or hyperthyroidism. However, in an important subgroup of patients the results of TFTs can seem confusing, either by virtue of being discordant with the clinical picture or because they appear incongruent with each other [e.g. raised thyroid hormones (TH), but with non-suppressed thyrotropin (TSH); raised TSH, but with normal TH]. In such cases, it is important first to revisit the clinical context, and to consider potential confounding factors, including alterations in normal physiology (e.g. pregnancy), intercurrent (non-thyroidal) illness, and medication usage (e.g. thyroxine, amiodarone, heparin). Once these have been excluded, laboratory artefacts in commonly used TSH or TH immunoassays should be screened for, thus avoiding unnecessary further investigation and/or treatment in cases where there is assay interference. In the remainder, consideration should be given to screening for rare genetic and acquired disorders of the hypothalamic-pituitary-thyroid (HPT) axis [e.g. resistance to thyroid hormone (RTH), thyrotropinoma (TSHoma)]. Here, we discuss the main pitfalls in the measurement and interpretation of TFTs, and propose a structured algorithm for the investigation and management of patients with anomalous/discordant TFTs. PMID:24275187

  13. Pitfalls and Limitations of SPECT, PET, and Therapeutic Radiopharmaceuticals.

    PubMed

    Ballinger, James R

    2015-09-01

    Radiopharmaceuticals are widely accepted to be a very safe class of drugs, with very few adverse reactions and unexpected biodistributions. However, problems can arise because of technical issues in manufacture or reconstitution, patient preparation, or drug administration. This review presents highlights of issues that have arisen in the newer classes of radiopharmaceuticals in the last 20 years and expands the scope of the previous report to include PET and therapeutic radiopharmaceuticals. Variations in the "quality" of the eluate of a (99)Mo/(99m)Tc generator remain a major issue. Several of the newer (99m)Tc tracers require a heating step in preparation that can also lead to unacceptably low radiochemical purity. Radiolytic breakdown can be a problem with all classes of radiopharmaceuticals. Many of the newer radiopharmaceuticals localize by receptor- or transporter-mediated processes and thus can be affected by other drugs, making patient preparation more important than ever. Therapeutic radiopharmaceuticals may require coadministration of radioprotectant regimens, such as the use of lysine-arginine infusions with radiopeptide therapy. Extravasation can have serious consequences with therapeutic radiopharmaceuticals. Adverse reactions to newer radiopharmaceuticals remain rare, though may increase because of coadministration of agents such as contrast media. However, there is known to be underreporting of minor adverse reactions. Knowledge of the pitfalls that can occur with radiopharmaceuticals is important in the interpretation of nuclear medicine images and optimal patient care. PMID:26278857

  14. Ischaemic conditioning: pitfalls on the path to clinical translation

    PubMed Central

    Przyklenk, Karin

    2015-01-01

    The development of novel adjuvant strategies capable of attenuating myocardial ischaemia-reperfusion injury and reducing infarct size remains a major, unmet clinical need. A wealth of preclinical evidence has established that ischaemic ‘conditioning’ is profoundly cardioprotective, and has positioned the phenomenon (in particular, the paradigms of postconditioning and remote conditioning) as the most promising and potent candidate for clinical translation identified to date. However, despite this preclinical consensus, current phase II trials have been plagued by heterogeneity, and the outcomes of recent meta-analyses have largely failed to confirm significant benefit. As a result, the path to clinical application has been perceived as ‘disappointing’ and ‘frustrating’. The goal of the current review is to discuss the pitfalls that may be stalling the successful clinical translation of ischaemic conditioning, with an emphasis on concerns regarding: (i) appropriate clinical study design and (ii) the choice of the ‘right’ preclinical models to facilitate clinical translation. PMID:25560903

  15. Pitfalls and Limitations of Radionuclide Renal Imaging in Adults.

    PubMed

    Keramida, Georgia; James, Jacqueline M; Prescott, Mary C; Peters, Adrien Michael

    2015-09-01

    To understand pitfalls and limitations in adult renography, it is necessary to understand firstly the physiology of the kidney, especially the magnitude and control of renal blood flow, glomerular filtration rate and tubular fluid flow rate, and secondly the pharmacokinetics and renal handling of the three most often used tracers, Tc-99m-mercaptoacetyltriglycine (MAG3), Tc-99m-diethylene triamine pentaacetic acid (DTPA) and Tc-99m-dimercaptosuccinic acid (DMSA). The kidneys may be imaged dynamically with Tc-99m-MAG3 or Tc-99m-DTPA, with or without diuretic challenge, or by static imaging with Tc-99m-DMSA. Protocols are different according to whether the kidney is native or transplanted. Quantitative analysis of dynamic data includes measurement of renal vascularity (important for the transplanted kidney), absolute tracer clearance rates, differential renal function (DRF) and response to diuretic challenge. Static image reveals functional renal parenchymal damage, both focal and global, is useful in the clinical management of obstructive uropathy, renal stone disease and hypertension (under angiotensin converting enzyme inhibition), and is the preferred technique for determining DRF. Diagnosis based on morphological appearances is important in transplant management. Even though nuclear medicine is now in the era of hybrid imaging, renal imaging remains an important subspecialty in nuclear medicine and requires a sound basing in applied physiology, the classical supporting discipline of nuclear medicine. PMID:26278854

  16. Pitfalls of adrenal imaging with chemical shift MRI.

    PubMed

    Schieda, N; Al Dandan, O; Kielar, A Z; Flood, T A; McInnes, M D F; Siegelman, E S

    2014-11-01

    Chemical shift (CS) MRI of the adrenal glands exploits the different precessional frequencies of fat and water protons to differentiate the intracytoplasmic lipid-containing adrenal adenoma from other adrenal lesions. The purpose of this review is to illustrate both technical and interpretive pitfalls of adrenal imaging with CS MRI and emphasize the importance of adherence to strict technical specifications and errors that may occur when other imaging features and clinical factors are not incorporated into the diagnosis. When performed properly, the specificity of CS MRI for the diagnosis of adrenal adenoma is over 90%. Sampling the in-phase and opposed-phase echoes in the correct order and during the same breath-hold are essential requirements, and using the first echo pair is preferred, if possible. CS MRI characterizes more adrenal adenomas then unenhanced CT but may be non-diagnostic in a proportion of lipid-poor adenomas; CT washout studies may be able to diagnose these lipid-poor adenomas. Other primary and secondary adrenal tumours and supra-renal disease entities may contain lipid or gross fat and mimic adenoma or myelolipoma. Heterogeneity within an adrenal lesion that contains intracytoplasmic lipid could be due to myelolipoma, lipomatous metaplasia of adenoma, or collision tumour. Correlation with previous imaging, other imaging features, clinical history, and laboratory investigations can minimize interpretive errors. PMID:25062926

  17. Diagnostics of eosinophilic esophagitis: Clinical, endoscopic, and histologic pitfalls

    PubMed Central

    Dellon, Evan S.

    2014-01-01

    Eosinophilic esophagitis (EoE) is currently defined as an immune-mediated chronic esophageal disorder that is diagnosed using both clinical and pathologic information. A series of consensus diagnostic guidelines for EoE have brought a measure of consistency to the field, but in practice the diagnosis of EoE can be challenging. Typical clinical symptoms of EoE, including dysphagia, heartburn, and chest pain, can overlap with gastroesophageal reflux disease (GERD), which itself is a common indication for performing endoscopic evaluation. The endoscopic findings of EoE, such as esophageal rings, strictures, linear furrows, and white exudates are not specific. Esophageal eosinophilia, the histologic hallmark of EoE, is also not pathognomonic and can be seen in a range of conditions. Further complicating the diagnosis of EoE is the newly recognized entity of proton pump inhibitor-responsive esophageal eosinophilia (PPI-REE), a condition that must be excluded prior to confirming a diagnosis of EoE. This paper will review the current diagnostic criteria for EoE, and discuss multiple clinical, endoscopic, and histologic pitfalls in making the diagnosis of EoE. PMID:24603380

  18. Pitfalls in the biological diagnosis of common hemoglobin disorders.

    PubMed

    Wajcman, Henri; Moradkhani, Kamran

    2015-01-01

    In West-European countries, hemoglobin disorders are no more rare diseases. Programs for diagnosis of heterozygous carriers have been established to prevent cases with major sickle cell disease or thalassemias. These studies have been done essentially by high performance liquid chromatography on cation-exchange columns and electrophoresis (mostly capillary electrophoresis). They have been done through systematic population studies or premarital diagnosis. We describe in this work the frequent or rare pitfalls encountered, which led to false negative or positive diagnosis both in the field of sickle cell disease and thalassemias. In the absence of a well identified hemoglobin disorder in the proband's family, it is a rule that the use of a single test is insufficient to identify formally HbS. The presence of HbS could also be masked by another hemoglobin abnormality. The sole measurement of HbA2 level is insufficient to characterize a thalassemic trait: this level needs always to be interpreted considering RBC parameters and iron metabolic status. In difficult cases, the definitive answer may require a family study and/or a molecular genetic characterization. PMID:26489811

  19. Cutaneous epithelioid angiosarcoma: a neoplasm with potential pitfalls in diagnosis.

    PubMed

    Mobini, Narciss

    2009-03-01

    Angiosarcoma (AS) is a rare neoplasm. Cutaneous AS is the most common form of AS. The epithelioid variant of the disease, however, is a rare entity. This subset can histologically mimic non-vascular neoplasms and impose serious challenges in reaching the correct diagnosis. We present five patients with cutaneous epithelioid angiosarcoma (EAS); in none, the clinical diagnosis included a vascular lesion. Three patients had history of breast conservation surgery with/without radiation therapy. Other patients had no previous radiation, and there was no lymphedema in any of the cases. The histopathological examination of the biopsy specimens by hematoxylin and eosin method was not suggestive of a malignant vascular neoplasm initially and the differential diagnoses included carcinoma, malignant melanoma and atypical lymphoid infiltrate. Only after performing immunohistochemical studies that included vascular markers, a definitive diagnosis was possible. Some cases showed unusual histopathological features. Cutaneous EAS is a rare variant of cutaneous AS that can mimic a variety of more common, non-vascular neoplasms, creating a major pitfall in the diagnosis. A careful and thorough histopathological examination and a high index of suspicion, along with appropriate immunohistochemical evaluation, can help reach a correct diagnosis and provide optimal patient care. PMID:19220634

  20. Molecular testing in oncology: problems, pitfalls and progress.

    PubMed

    O'Brien, Cathal P; Taylor, Sarah E; O'Leary, John J; Finn, Stephen P

    2014-03-01

    Recent advances in the understanding of the molecular basis of cancer and the development of molecular diagnostics based on this knowledge have done much to progress the fields of oncology and pathology. Technological developments such as Next Generation Sequencing (NGS) and multiplex assays have made feasible the widespread adoption of molecular diagnostics for clinical use. While these developments and advances carry much promise, there are pitfalls to implementing this testing. Choosing appropriate biomarkers is a vital first step for clinical use and being able to understand the complex relationship between predictive and prognostic biomarkers is a crucial component of this. Testing for standard of care biomarkers is not straightforward, one must choose carefully between clinical trial assays, assays that analyse the same biological phenomenon or surrogate biomarkers. Sample heterogeneity and population specific difference is assays may skew results and must be controlled for at the assay design stage. At a technical level, NGS has the potential to revolutionise laboratory practice and approaches to cancer treatment. However, use of this technology requires careful planning and implementation if one is to avoid technical and ethical quagmires. Finally, with FDA regulation of companion diagnostics one may be limited to therapy specific assays. PMID:24472389

  1. Computed Tomography Angiography in Microsurgery: Indications, Clinical Utility, and Pitfalls

    PubMed Central

    Lee, Gordon K.; Fox, Paige M.; Riboh, Jonathan; Hsu, Charles; Saber, Sepideh; Rubin, Geoffrey D.; Chang, James

    2013-01-01

    Objective: Computed tomographic angiography (CTA) can be used to obtain 3-dimensional vascular images and soft-tissue definition. The goal of this study was to evaluate the reliability, usefulness, and pitfalls of CTA in preoperative planning of microvascular reconstructive surgery. Methods: A retrospective review of patients who obtained preoperative CTA in preparation for planned microvascular reconstruction was performed over a 5-year period (2001–2005). The influence of CTA on the original operative plan was assessed for each patient, and CTA results were correlated to the operative findings. Results: Computed tomographic angiography was performed on 94 patients in preparation for microvascular reconstruction. In 48 patients (51%), vascular abnormalities were noted on CTA. Intraoperative findings correlated with CTA results in 97% of cases. In 42 patients (45%), abnormal CTA findings influenced the original operative plan, such as the choice of vessels, side of harvest, or nature of the reconstruction (local flap instead of free tissue transfer). Technical difficulties in performing CTA were encountered in 5 patients (5%) in whom interference from external fixation devices was the main cause. Conclusions: This large study of CTA obtained for preoperative planning of reconstructive microsurgery at both donor and recipient sites study demonstrates that CTA is safe and highly accurate. Computed tomographic angiography can alter the surgeon's reconstructive plan when abnormalities are noted preoperatively and consequently improve results by decreasing vascular complication rates. The use of CTA should be considered for cases of microsurgical reconstruction where the vascular anatomy may be questionable. PMID:24023972

  2. Promises and Pitfalls of High-Throughput Biological Assays.

    PubMed

    Finak, Greg; Gottardo, Raphael

    2016-01-01

    This chapter discusses some of the pitfalls encountered when performing biomedical research involving high-throughput "omics" data and presents some strategies and guidelines that researchers should follow when undertaking such studies. We discuss common errors in experimental design and data analysis that lead to irreproducible and non-replicable research and provide some guidelines to avoid these common mistakes so that researchers may have confidence in study outcomes, even if the results are negative. We discuss the importance of ranking and prespecifying hypotheses, performing power analysis, careful experimental design, and preplanning of statistical analyses in order to avoid the "fishing expedition" data analysis strategy, which is doomed to fail. The impact of multiple testing on false-positive rates is discussed, particularly in the context of the analysis of high-throughput data, and methods to correct for it are presented, as well as approaches to detect and correct for experimental biases and batch effects, which often plague high-throughput assays. We highlight the importance of sharing data and analysis code to facilitate reproducibility and present tools and software that are appropriate for this purpose. PMID:27115636

  3. Genetics of Type 2 Diabetes—Pitfalls and Possibilities

    PubMed Central

    Prasad, Rashmi B.; Groop, Leif

    2015-01-01

    Type 2 diabetes (T2D) is a complex disease that is caused by a complex interplay between genetic, epigenetic and environmental factors. While the major environmental factors, diet and activity level, are well known, identification of the genetic factors has been a challenge. However, recent years have seen an explosion of genetic variants in risk and protection of T2D due to the technical development that has allowed genome-wide association studies and next-generation sequencing. Today, more than 120 variants have been convincingly replicated for association with T2D and many more with diabetes-related traits. Still, these variants only explain a small proportion of the total heritability of T2D. In this review, we address the possibilities to elucidate the genetic landscape of T2D as well as discuss pitfalls with current strategies to identify the elusive unknown heritability including the possibility that our definition of diabetes and its subgroups is imprecise and thereby makes the identification of genetic causes difficult. PMID:25774817

  4. Pitfalls in staging uterine neoplasm with imaging: a review.

    PubMed

    Kinkel, K

    2006-01-01

    This review analyzes current pitfalls in pretreatment staging of endometrial and cervical carcinoma with magnetic resonance imaging (MRI) based on a critical review of the literature. Technical, patient, and tumor-related characteristics were analyzed to improve further staging of uterine neoplasm with MRI. For endometrial carcinoma staging, contrast-enhanced dynamic imaging appears essential to avoid false-positive findings for deep myometrial invasion by better delineating tumor from normal myometrium. However, leiomyomas, adenomyosis, and grade 3 tumors provide difficulties in staging for pathologists and radiologists. Slice orientation perpendicular to the long axis of the cervical channel might improve false-negative findings for deep stromal invasion on T2-weighted images in endometrial and cervical cancer. Contrast-enhanced sequences do not improve diagnosis of parametrial or vaginal invasion in cervical cancer. Assessment of lymph node invasion by any imaging modality has limited sensitivity in detecting lymph node metastasis smaller than 5 mm. Knowledge of diagnostic criteria is critical to avoid false-negative findings for bladder wall invasion. Higher spatial resolution with dedicated multichannel pelvic phase array coils, smaller fields of view and section thickness, and careful comparison of T2-weighted and contrast-enhanced sequences are strategies that might avoid misinterpretation of pelvic MRI in staging uterine neoplasm. PMID:16333697

  5. Massively Multiplayer Online Games as Living Laboratories: Opportunities and Pitfalls

    NASA Astrophysics Data System (ADS)

    Ducheneaut, Nicolas

    The digital nature of online games makes them particularly amenable to large-scale, automated data collection and analysis; so researchers have begun to use them as living laboratories to test or refine the existing theories of human behavior. On the basis of several years of intensive data collection in several massively multiplayer online games, this chapter addresses three problems concerning validity and generalizability that must be taken into account. First, each game has a set of laws that steer player behavior, thereby introducing confounding factors that have to be taken into account by the researcher. Second, games attract skewed samples of players, and players may adopt transformed personalities inside the game world, which puts into question the validity of extending findings from observations in the digital realm into the physical one. Third, the lack of a clear boundary defining the "game space," illustrated by the many websites and forums for popular games, raises the question of whether online games themselves capture the totality of the user's experience. The problematic mapping between "real-world" behaviors and those in online games presents research opportunities as well as pitfalls that need to be avoided.

  6. Reframing science communication: How the use of metaphor, rhetoric, and other tools of persuasion can strengthen the public understanding of science (without weakening the integrity of the scientific process)

    NASA Astrophysics Data System (ADS)

    Soderberg, Jeanne

    This paper is about "truthiness", its resulting impact on the public understanding of science (and subsequently science policy), and why scientists need to learn how to navigate truthiness in order to ensure that the scientific body of knowledge is both preserved and shared. In order to contend with truthiness, scientists must understand and acknowledge how people receive and process information, how they form their reactions and opinions about it, and how they can be manipulated by various agencies and players to feel and think in certain ways. In order to accomplish these objectives, scientists must also understand various aspects of culture, language, psychology, neuroscience, and communication. Most importantly, scientists must recognize their own humanity, and learn how to accept and work with their own human boundaries. Truth can indeed be beauty. And, there is absolutely nothing unscientific about creating beauty in order to demonstrate and explain truth.

  7. Scientific entrepreneurship in the materials and life science industries.

    PubMed

    Dinglasan, Jose Amado; Anderson, Darren J; Thomas, Keith

    2011-01-01

    Scientists constantly generate great ideas in the laboratory and, as most of us were meant to believe, we should publish or perish. After all, what use is a great scientific idea if it is not shared with the rest of the scientific community? What some scientists forget is that a good idea can be worth something - sometimes it can be worth a lot (of money)! What do you do if you believe that your idea has some commercial potential? How do you turn this idea into a business? This chapter gives the aspiring scientific entrepreneur some (hopefully) valuable advice on topics like choosing the right people for your management team, determining inventorship of the technology and ownership shares in the new company, protecting your intellectual property, and others; finally, it describes some of the various pitfalls you may encounter when commercializing an early stage technology and instructions on how to avoid them. PMID:21424462

  8. Development of a practical tool to measure the impact of publications on the society based on focus group discussions with scientists

    PubMed Central

    2011-01-01

    Background A 'societal impact factor' that complements the scientific impact factor would contribute to a more comprehensive evaluation of scientific research. In order to develop a practical tool for its assessment, it is important to learn about perceptions of scientists on how to measure a societal impact factor. Methods This qualitative study presents the development of a practical tool to measure the societal impact of publications based on 8 focus group discussions with 24 biomedical scientists at the Medical University Vienna between May 2008 and May 2009. Topics focused on (1) features of an ideal tool, (2) criteria that should be considered in the assessment, and (3) the identification of practical pitfalls. In an iterative exercise involving the repeated application of the drafted tool to scientific papers, criteria for the assessment were refined. A small-scale exercise to evaluate the tool in terms of its comprehensibility, relevance and practicability was conducted using questionnaires for 6 external experts in leading positions of public health, and yielded acceptable results. Results The tool developed consists of three quantitative dimensions, that is (1) the aim of a publication, (2) the efforts of the authors to translate their research results, and, if translation was accomplished, (3) (a) the size of the area where translation was accomplished (regional, national or international), (b) its status (preliminary versus permanent) and (c) the target group of the translation (individuals, subgroup of population, total population). Conclusions Focus group discussions with scientists suggested that the societal impact factor of a publication should consider the effect of the publication in a wide set of non-scientific areas, but also the motivation behind the publication, and efforts by the authors to translate their findings. The proposed tool provides some valuable insights for further research and practical applications in the topic area. PMID

  9. Social Network Analysis for the U.S. National Climate Assessment: A Tool for Improving the Transmission of Scientific Information to Public Audiences

    NASA Astrophysics Data System (ADS)

    Maldonado, J.; Frank, K.; Chen, T.

    2014-12-01

    The U.S. National Climate Assessment (NCA) is working with experts from Michigan State University to use social network analysis to analyze the NCA's outreach and engagement activities to improve upon these components for the ongoing, sustained assessment. The social network analysis diagrams the NCA's engagement with stakeholders around the country, showing how the network of stakeholders with whom the NCA engaged expanded over the course of the Third NCA. Showing the avenues for how information moves through a social system, social network analysis can be used to inform gaps in the types and locations of stakeholders engaged with, suggesting places to improve the flow of information. The social network analysis helped illuminate which stakeholders were involved in the Third NCA and which were missed, what key networks the NCA has engaged with, and to what extent these relationships have been sustained. This presentation will include examples of how the outcomes of the social network analysis can be used to better understand the engagement and outreach with a group of stakeholders, what networks in a particular group were engaged with, what the gaps were, and ways to improve in the future. It will also include suggestions for how to more effectively translate climate change information to stakeholders. This information can help inform the ongoing NCA on how to more successfully reach stakeholder groups and improve its public engagement and outreach.

  10. Scientific Resource EXplorer

    NASA Astrophysics Data System (ADS)

    Xing, Z.; Wormuth, A.; Smith, A.; Arca, J.; Lu, Y.; Sayfi, E.

    2014-12-01

    Inquisitive minds in our society are never satisfied with curatedimages released by a typical public affairs office. They always want tolook deeper and play directly on original data. However, most scientificdata products are notoriously hard to use. They are immensely large,highly distributed and diverse in format. In this presentation,we will demonstrate Resource EXplorer (REX), a novel webtop applicationthat allows anyone to conveniently explore and visualize rich scientificdata repositories, using only a standard web browser. This tool leverageson the power of Webification Science (w10n-sci), a powerful enabling technologythat simplifies the use of scientific data on the web platform.W10n-sci is now being deployed at an increasing number of NASA data centers,some of which are the largest digital treasure troves in our nation.With REX, these wonderful scientific resources are open for teachers andstudents to learn and play.

  11. Abiding by codes of ethics and codes of conduct imposed on members of learned and professional geoscience institutions and - a tiresome formality or a win-win for scientific and professional integrity and protection of the public?

    NASA Astrophysics Data System (ADS)

    Allington, Ruth; Fernandez, Isabel

    2015-04-01

    In 2012, the International Union of Geological Sciences (IUGS) formed the Task Group on Global Geoscience Professionalism ("TG-GGP") to bring together the expanding network of organizations around the world whose primary purpose is self-regulation of geoscience practice. An important part of TG-GGP's mission is to foster a shared understanding of aspects of professionalism relevant to individual scientists and applied practitioners working in one or more sectors of the wider geoscience profession (e.g. research, teaching, industry, geoscience communication and government service). These may be summarised as competence, ethical practice, and professional, technical and scientific accountability. Legal regimes for the oversight of registered or licensed professionals differ around the world and in many jurisdictions there is no registration or licensure with the force of law. However, principles of peer-based self-regulation universally apply. This makes professional geoscience organisations ideal settings within which geoscientists can debate and agree what society should expect of us in the range of roles we fulfil. They can provide the structures needed to best determine what expectations, in the public interest, are appropriate for us collectively to impose on each other. They can also provide the structures for the development of associated procedures necessary to identify and discipline those who do not live up to the expected standards of behaviour established by consensus between peers. Codes of Ethics (sometimes referred to as Codes of Conduct), to which all members of all major professional and/or scientific geoscience organizations are bound (whether or not they are registered or hold professional qualifications awarded by those organisations), incorporate such traditional tenets as: safeguarding the health and safety of the public, scientific integrity, and fairness. Codes also increasingly include obligations concerning welfare of the environment and

  12. Pitfall Traps and Mini-Winkler Extractor as Complementary Methods to Sample Soil Coleoptera.

    PubMed

    Carneiro, A C; Batistella, D A; Battirola, L D; Marques, M I

    2016-02-01

    We compared abundance, species richness, and capture efficiency with pitfall traps and mini-Winkler extractors to examine their use as complementary methods for sampling soil Coleoptera during dry (2010) and high water seasons (2011) in three areas, including inundated and non-inundated regions, in the Pantanal of Poconé, Mato Grosso, Brazil. We paired treatments with two 10 × 10 m plots in inundated and non-inundated locations that were repeated three times in each location for a total of 18 plots. In each plot, we used nine pitfall traps and collected 2 m(2) of leaf litter and surface soil samples with mini-Winkler extractors. We collected a total of 4260 adult beetles comprising 36 families, 113 genera, and 505 species. Most were caught in pitfalls (69%) and the remainder in the mini-Winkler extractors (31%). Each method provided distinct information about the beetle community: 252 species were captured only in pitfall traps, 147 using only the mini-Winkler extractors, and these methods shared another 106 species. Pitfall and mini-Winkler contribute in different ways for the sampling of the soil beetle community, and so they should be considered complementary for a more thorough assessment of community diversity. PMID:26493175

  13. TU-D-BRD-01: Image Guided SBRT II: Challenges ' Pitfalls

    SciTech Connect

    Chang, Z; Yin, F; Cho, J

    2014-06-15

    Stereotactic body radiation therapy (SBRT) has been effective treatment for the management of various diseases, which often delivers high radiation dose in a single or a few fractions. SBRT therefore demands precise treatment delivery to the tumor while sparing adjacent healthy tissue. Recent developments in image guidance enable target localization with increased accuracy. With such improvements in localization, image-guided SBRT has been widely adopted into clinical practice. In SBRT, high radiation dose is generally delivered with small fields. Therefore, it is crucial to accurately measure dosimetric data for the small fields during commissioning. In addition, image-guided SBRT demands accurate image localization to ensure safety and quality of patient care. Lately, the reports of AAPM TG 142 and TG 104 have been published and added recommendations for imaging devices that are integrated with the linear accelerator for SBRT. Furthermore, various challenges and potential pitfalls lie in the clinical implementation of image-guided SBRT. In this lecture, these challenges and pitfalls of image-guided SBRT will be illustrated and discussed from dosimetric, technical and clinical perspectives.Being a promising technique, image-guided SBRT has shown great potentials, and will lead to more accurate and safer SBRT treatments. Learning Objectives: To understand dosimetric challenges and pitfalls for IGRT application in SBRT. To understand major clinical challenges and pitfalls for IGRT application in SBRT. To understand major technical challenges and pitfalls for IGRT application in SBRT.

  14. PLAGIARISM IN SCIENTIFIC PUBLISHING

    PubMed Central

    Masic, Izet

    2012-01-01

    Scientific publishing is the ultimate product of scientist work. Number of publications and their quoting are measures of scientist success while unpublished researches are invisible to the scientific community, and as such nonexistent. Researchers in their work rely on their predecessors, while the extent of use of one scientist work, as a source for the work of other authors is the verification of its contributions to the growth of human knowledge. If the author has published an article in a scientific journal it cannot publish the article in any other journal h with a few minor adjustments or without quoting parts of the first article, which are used in another article. Copyright infringement occurs when the author of a new article with or without the mentioning the author used substantial portions of previously published articles, including tables and figures. Scientific institutions and universities should,in accordance with the principles of Good Scientific Practice (GSP) and Good Laboratory Practices (GLP) have a center for monitoring,security, promotion and development of quality research. Establish rules and compliance to rules of good scientific practice are the obligations of each research institutions,universities and every individual-researchers,regardless of which area of science is investigated. In this way, internal quality control ensures that a research institution such as a university, assume responsibility for creating an environment that promotes standards of excellence, intellectual honesty and legality. Although the truth should be the aim of scientific research, it is not guiding fact for all scientists. The best way to reach the truth in its study and to avoid the methodological and ethical mistakes is to consistently apply scientific methods and ethical standards in research. Although variously defined plagiarism is basically intended to deceive the reader’s own scientific contribution. There is no general regulation of control of

  15. Plagiarism in scientific publishing.

    PubMed

    Masic, Izet

    2012-12-01

    Scientific publishing is the ultimate product of scientist work. Number of publications and their quoting are measures of scientist success while unpublished researches are invisible to the scientific community, and as such nonexistent. Researchers in their work rely on their predecessors, while the extent of use of one scientist work, as a source for the work of other authors is the verification of its contributions to the growth of human knowledge. If the author has published an article in a scientific journal it cannot publish the article in any other journal h with a few minor adjustments or without quoting parts of the first article, which are used in another article. Copyright infringement occurs when the author of a new article with or without the mentioning the author used substantial portions of previously published articles, including tables and figures. Scientific institutions and universities should,in accordance with the principles of Good Scientific Practice (GSP) and Good Laboratory Practices (GLP) have a center for monitoring,security, promotion and development of quality research. Establish rules and compliance to rules of good scientific practice are the obligations of each research institutions,universities and every individual-researchers,regardless of which area of science is investigated. In this way, internal quality control ensures that a research institution such as a university, assume responsibility for creating an environment that promotes standards of excellence, intellectual honesty and legality. Although the truth should be the aim of scientific research, it is not guiding fact for all scientists. The best way to reach the truth in its study and to avoid the methodological and ethical mistakes is to consistently apply scientific methods and ethical standards in research. Although variously defined plagiarism is basically intended to deceive the reader's own scientific contribution. There is no general regulation of control of

  16. Public Affairs.

    ERIC Educational Resources Information Center

    Snow, C. P.

    In this book effects of technological developments on world conditions are discussed on the basis of the author's public statements made between 1959-70. A total of seven pieces is presented under the headings: The Two Cultures and the Scientific Revolution, The Two Cultures: A Second Look, The Case of Leavis and the Serious Case, Science and…

  17. Ethics in publication.

    PubMed

    Wallace, Michael B; Siersema, Peter D

    2015-09-01

    Publication of scientific manuscripts remains our core method of sharing knowledge and advanced scientific inquiry. Pressures to publish for reasons other than pure discovery have the potential to corrupt this process. The core principles of scientific ethics outlined above provide guidance on how to maintain the integrity of our scientific process.We, as journal editors, are committed to the advancement of scientific knowledge and the ethical process of publication. We do the best we can to make sure that the articles we publish fulfill all the criteria of a well-conducted study. PMID:26112677

  18. Ethics in publication.

    PubMed

    Wallace, Michael B; Siersema, Peter D

    2015-07-01

    Publication of scientific manuscripts remains our core method of sharing knowledge and advanced scientific inquiry. Pressures to publish for reasons other than pure discovery have the potential to corrupt this process. The core principles of scientific ethics outlined above provide guidance on how to maintain the integrity of our scientific process. We, as journal editors, are committed to the advancement of scientific knowledge and the ethical process of publication. We do the best we can to make sure that the articles we publish fulfill all the criteria of a well-conducted study. PMID:26099116

  19. Dermatoscopic pitfalls in differentiating pigmented Spitz naevi from cutaneous melanomas.

    PubMed

    Argenziano, G; Scalvenzi, M; Staibano, S; Brunetti, B; Piccolo, D; Delfino, M; De Rosa, G; Soyer, H P

    1999-11-01

    Epiluminescence microscopy (ELM, skin surface microscopy, dermoscopy, dermatoscopy) is a valuable method for improving the diagnostic accuracy in pigmented skin lesions. Specific ELM criteria are already recognized for differentiating pigmented Spitz naevi (PSN) from cutaneous melanomas (CM). Our purpose was to describe the ELM appearance of a series of PSN with emphasis on PSN and CM with overlapping features. Thirty-six consecutive patients with PSN, and three cases of CM (selected from a larger database) exhibiting ELM 'spitzoid' features, were evaluated clinically, dermatoscopically and histopathologically. Most PSN (27 of 36; 75%) displayed two typical ELM patterns, namely, the starburst (19 of 36; 53%) or the globular pattern (eight of 36; 22%), which were correlated to different histopathological findings. In nine of 36 (25%) PSN, atypical ELM features which are more commonly seen in CM were observed. These PSN with an atypical pattern were characterized by an uneven distribution of colours and structures, and an irregular diffuse pigmentation resembling blue-white veil or irregular extensions (black blotches). These atypical lesions mostly occurred in children and showed no history of growth. In contrast, in three examples of CM, the typical ELM criteria of malignancy were less recognizable and either the characteristic starburst or globular pattern usually seen in PSN was present. These three lesions occurred in adults and had a recent history of change in colour, shape or size. The overlap in ELM features of some PSN and CM represents a major diagnostic pitfall when ELM examination is considered alone. In these atypical cases, clinical history including the age of the patient may be the only clue to enable a correct diagnosis. PMID:10583158

  20. Pitfalls to avoid when introducing a cultural competency training initiative.

    PubMed

    Chun, Maria B J

    2010-06-01

    OBJECTIVES In an effort to provide preventive advice, this paper aims to acknowledge what has not worked with regard to cultural competency initiatives. A successful cultural competency training initiative should have lasting impact on its participants in terms of long-term, ideally permanent changes to attitudes, knowledge and skills resulting in the provision of optimum care, regardless of a patient's cultural background. Legal mandates mean there is an assumed need for cultural competency curricula and training programmes for medical students and postgraduate medical trainees. However, policy and practice have bypassed 'proof' that such programmes are effective and result in better patient care. Often only positive results are reported, which may minimise the difficulties involved in programme implementation. METHODS Utilising the example of a cultural competency initiative introduced into a postgraduate general surgery training programme, this paper discusses mistakes that were made during the implementation phase, particularly with regard to underestimating potential resistance by the trainees. Also presented are the lessons learned and efforts that were made to mitigate the problems that arose. None of what is discussed in this paper is new. However, the literature often does not discuss in detail the difficulties that can be or have been faced and how these obstacles can be adequately mitigated. CONCLUSIONS The glow of cultural competency training initiatives is fading in the light of higher expectations for an evidence base prior to acknowledgement that their introduction has had a positive impact. For these initiatives to advance, there needs to be a clear understanding of terms utilised, buy-in and a long-term commitment at both individual and organisational levels, and use of standardised and validated tools to measure outcomes. An understanding of potential pitfalls can help to advance cultural competency training to the next level, namely, a solid

  1. Androgens and doping tests: genetic variation and pit-falls

    PubMed Central

    Rane, Anders; Ekström, Lena

    2012-01-01

    The large variation in disposition known for most drugs is also true for anabolic androgenic steroids. Genetic factors are probably the single most important cause of this variation. Further, there are reasons to believe that there is a corresponding variation in efficacy of doping agents. Doped individuals employ a large variety of doping strategies in respect of choice of substance, dose, dose interval, duration of treatment and use of other drugs for enforcement of effects or correction of side effects. Metabolic steps up-stream and down-stream of testosterone are genetically variable and contribute substantially to the variation in disposition of testosterone, the most common doping agent in sports and in society. Large inter- and intra-ethnic variation in testosterone glucuronidation and excretion is described as well as the pit-falls in evaluation of testosterone doping test results. The hydrolysis and bioactivation of testosterone enanthate is also genetically variable yielding a 2–3 fold variation in excretion rate and serum concentration, thereby implicating a substantial variation in ‘efficacy’ of testosterone. Given this situation it is logical to adopt the new findings in the doping control programme. The population based cut-off level for the testosterone : epitestosterone ratio should be replaced by a Bayesian interpretation of consecutive tests in the same individual. When combined with the above genetic information the sensitivity of the test is considerably improved. The combination of the three approaches should reduce the rate of falsely negative or positive results and the number of expensive follow-up tests, stipulated by the World Anti-Doping Agency. PMID:22506612

  2. Nano(Q)SAR: Challenges, pitfalls and perspectives.

    PubMed

    Tantra, Ratna; Oksel, Ceyda; Puzyn, Tomasz; Wang, Jian; Robinson, Kenneth N; Wang, Xue Z; Ma, Cai Y; Wilkins, Terry

    2015-01-01

    Regulation for nanomaterials is urgently needed, and the drive to adopt an intelligent testing strategy is evident. Such a strategy will not only provide economic benefits but will also reduce moral and ethical concerns arising from animal testing. For regulatory purposes, such an approach is promoted by REACH, particularly the use of quantitative structure-activity relationships [(Q)SAR] as a tool for the categorisation of compounds according to their physicochemical and toxicological properties. In addition to compounds, (Q)SAR has also been applied to nanomaterials in the form of nano(Q)SAR. Although (Q)SAR in chemicals is well established, nano(Q)SAR is still in early stages of development and its successful uptake is far from reality. This article aims to identify some of the pitfalls and challenges associated with nano-(Q)SARs in relation to the categorisation of nanomaterials. Our findings show clear gaps in the research framework that must be addressed if we are to have reliable predictions from such models. Three major barriers were identified: the need to improve quality of experimental data in which the models are developed from, the need to have practical guidelines for the development of the nano(Q)SAR models and the need to standardise and harmonise activities for the purpose of regulation. Of these three, the first, i.e. the need to improve data quality requires immediate attention, as it underpins activities associated with the latter two. It should be noted that the usefulness of data in the context of nano-(Q)SAR modelling is not only about the quantity of data but also about the quality, consistency and accessibility of those data. PMID:25211549

  3. Total sacrectomy for recurrent rectal cancer – A case report featuring technical details and potential pitfalls

    PubMed Central

    Melich, George; Weber, Michael; Stein, Barry; Minutolo, Vincenzo; Arena, Manuel; Arena, Goffredo O.

    2014-01-01

    INTRODUCTION Total sacrectomy for recurrent rectal cancer is controversial. However, recent publications suggest encouraging outcomes with high sacral resections. We present the first case report describing technical aspects, potential pitfalls and treatment of complications associated with total sacrectomy performed as a treatment of recurrent rectal cancer. PRESENTATION OF CASE A fifty-three year old man was previously treated at another institution with a low anterior resection (LAR) followed by chemo-radiation and left liver tri-segmentectomy for metastatic rectal cancer. Three years following the LAR, the patient developed a recurrence at the site of colorectal anastomosis, manifesting clinically as a contained perforation, forming a recto-cutaneous fistula through the sacrum. Abdomino-perineal resection (APR) and complete sacrectomy were performed using an anterior–posterior approach with posterior spinal instrumented fusion and pelvic fixation using iliac crest bone graft. Left sided vertical rectus abdominis muscle flap and right sided gracilis muscle flap were used for hardware coverage and to fill the pelvic defect. One year after the resection, the patient remains disease free and has regained the ability to move his lower limbs against gravity. DISCUSSION The case described in this report features some formidable challenges due to the previous surgeries for metastatic disease, and the presence of a recto-sacral cutaneous fistula. An approach with careful surgical planning including considerationof peri-operative embolization is vital for a successful outcome of the operation. A high degree of suspicion for pseudo-aneurysms formation due infection or dislodgement of metallic coils is necessary in the postoperative phase. CONCLUSION Total sacrectomy for the treatment of recurrent rectal cancer with acceptable short-term outcomes is possible.A detailed explanation to the patient of the possible complications and expectations including the concept of a

  4. Common Pitfalls in Exposure and Response Prevention (EX/RP) for OCD

    PubMed Central

    Gillihan, Seth J.; Williams, Monnica T.; Malcoun, Emily; Yadin, Elna; Foa, Edna B.

    2012-01-01

    Obsessive-compulsive disorder (OCD) is a highly debilitating disorder. Fortunately there are treatments that help the majority of OCD sufferers. The behavioral treatment with the most empirical support for its efficacy is exposure and response prevention (EX/RP). Over the years in our supervision meetings and in our clinical practice we have noted a number of relatively common therapist pitfalls that decrease the effectiveness of EX/RP. These pitfalls include not encouraging patients to approach the most distressing situations, doing imaginal exposure when in vivo is called for (and vice versa), encouraging distraction during exposure, providing reassurance, failing to address the core fear, ineffective handling of mental compulsions, and difficulty working with close others in the patient’s life. In the current article we describe these common pitfalls and how to avoid them. PMID:22924159

  5. Linking Performance to Funding Outcomes for Public Institutions of Higher Education: The US Experience.

    ERIC Educational Resources Information Center

    Layzell, Daniel T.

    1998-01-01

    Discussion of funding for public colleges and universities in the United States looks at different mechanisms for measuring institutional performance, recent experiences with performance indicators for purposes of funding and the pitfalls and limitations of their use, the current status of performance-based funding in public colleges, and…

  6. Acute aortic syndrome-pitfalls on gated and non-gated CT scan.

    PubMed

    Husainy, Mohammad Ali; Sayyed, Farhina; Puppala, Sapna

    2016-08-01

    Acute aortic syndrome (AAS) is a life-threatening condition which includes aortic dissection (AD), penetrating aortic ulcer (PAU) and intramural hematoma (IMH). Multi-detector computed tomography (MDCT) plays a crucial role in the diagnosis of this condition and for further clinical follow-up. It is important for radiologists to be aware of common pitfalls in cardiac-gated and non-gated CT in diagnosing AAS. They should also be wary of common mimics of AAS which may make a significant difference towards management of these patients. In this review, we present from our practice some of the common pitfalls and mimics of AAS on MDCT. PMID:27220654

  7. Public health perspectives in cross-system practice: past, present and future.

    PubMed

    Bada Math, Suresh; Moirangthem, Sydney; Kumar, C Naveen

    2015-01-01

    Cross-system practice is widely prevalent in Indian settings. The recent policy decisions of the Government of India and the legalisation of cross-system practice in various states have brought this issue into the limelight once again. We aim to critically evaluate this issue from the philosophical, academic, and public health perspectives, as well as with reference to training. On the one hand, students of traditional Indian medicine are being introduced to allopathy without philosophical backing, practice based on the aetiological model and training in modern pharmacology. In addition, pharmaceutical industries are wooing AYUSH practitioners and their prescription patterns have already been "allopathised". As for the allopathic system, it is witnessing enormous scientific advances and growing increasingly complicated. The medicines are risky and also associated with many life-threatening side-effects. Meanwhile, the government is grappling with the humungous problem of ensuring health services for all. The government's intention is to expand the reach of health services by allowing cross-system practice, but the issue has much wider ramifications. The authors believe that before cross-system practice is allowed, there is a need for a comprehensive and deeper understanding of all the benefits and pitfalls of such as system. A few of these are discussed in this article. Specifically, we delve into the philosophical issues, syllabus and training, advances in medical technology, and larger public health perspectives. We end by suggesting a few steps that may help to improve public health in the country. PMID:26058367

  8. What Do Researchers Say about Scientific Literacy in Schools?

    ERIC Educational Resources Information Center

    McGregor, Debbie; Kearton, Ginny

    2010-01-01

    This article is the second in a thread of three pieces about scientific literacy. The first, written by Edgar Jenkins, provided an introduction to scientific literacy within the context of citizenship and the ways that scientific literacy might be interpreted by those with a concern about public understanding of science or the public engagement…

  9. Export bill and scientific exchanges

    NASA Astrophysics Data System (ADS)

    President Ronald Reagan has signed into law the reauthorization of the Export Administration Act (EAA), first passed in 1979. The amended version of the law, signed July 12, includes a policy statement in support of “vigorous scientific enterprise. . .in accordance with applicable provisions of law. . .by means of publication, teaching, conferences, and other forms of scholarly exchange.”

  10. Academic Staff and Scientific Production.

    ERIC Educational Resources Information Center

    Kyvik, Svein

    1993-01-01

    A survey of tenured faculty in four Norwegian universities investigated publication and scientific productivity patterns in a three-year period. Analysis of results suggests underlying reasons for differences between individuals, age groups, and gender groups and implications for administrative policy to support productivity. (MSE)

  11. Scientific Reasoning: No Child's Play

    ERIC Educational Resources Information Center

    Cavanagh, Sean

    2009-01-01

    The students, from the Academy of the Americas, a public school a few miles from downtown, are being asked to do the painstaking work of science, in an unlikely setting. It's part of a curriculum and professional-development program called BioKIDS, which seeks to build students' skill in complex scientific reasoning. The approach goes well beyond…

  12. Quantitative assessment of scientific quality

    NASA Astrophysics Data System (ADS)

    Heinzl, Harald; Bloching, Philipp

    2012-09-01

    Scientific publications, authors, and journals are commonly evaluated with quantitative bibliometric measures. Frequently-used measures will be reviewed and their strengths and weaknesses will be highlighted. Reflections about conditions for a new, research paper-specific measure will be presented.

  13. Possibilities and Pitfalls of a Public Health Agenda for Physical Education

    ERIC Educational Resources Information Center

    O'Sullivan, Mary

    2004-01-01

    The 1996 Surgeon General?s Report (SGR), "Physical Activity and Health," was one of the more significant U.S. Federal documents to outline national priorities for health and physical activity. In this monograph Marlene Tappe and Charlene Burgeson and Stephen Cone remind us that "Physical Activity and Health" was the third in a series of Surgeon…

  14. Land-Grant Extension: Defining Public Good and Identifying Pitfalls in Evaluation

    ERIC Educational Resources Information Center

    Collins, Christopher S.

    2015-01-01

    Land-grant extension is an ongoing example of higher education outreach and community engagement. Population, food, climate, and geographic isolation all factor into the importance of producing and facilitating agricultural knowledge. This qualitative study took place in a geographically isolated region with potential food security issues to…

  15. Scientific activity and needs among medical oncology units in sicily: a survey of the italian association of medical oncology.

    PubMed

    Amadio, P; Bordonaro, R; Borsellino, N; Butera, A; Caruso, M; Ferraù, F; Russello, R; Savio, G; Valenza, R; Zerilli, F; Gebbia, V

    2010-02-01

    In the era of targeted therapies and combined modalities of treatment, scientific research plays a role of paramount importance in improving knowledge of cancer treatment. The aim of this survey was to review the scientific activity of medical oncology units in Sicily and to analyze their needs and possible pitfalls in order to improve future scientific cooperation.The regional section of the Italian Association of medical Oncology (AIOM) approved this survey in November, 2007. A systematic review of scientific activity produced by medical oncology units in Sicily during the last 5 years has been reviewed. papers dealing with solid tumors reported in the pubmed web site have been included in the analysis. Data were reported as absolute number of published papers and impact factor per medical oncology unit and also as a ratio between global impact factor and the number of personnel working in each single unit to analyze scientific production according to the workforce of each institution.We identified a total of 283 papers reported in pubmed between 2004 and march, 2009. The mean number of publications/unit was 10.9 with a range of 0-50. The mean number of publications/year was 11.7 with a range of 0.2-10. The 15 units included in the impact factor evaluation published 252 papers with a total impact factor of 1014.6 points in 5 years with a mean of 63.4 points per institution and a mean of 4.02 points/paper. However only four medical oncology units reported a cumulative 5-year impact factor >100 points.This survey has shown that a minority of medical oncology units in Sicily is constantly involved in clinical research although at different levels of activity. Overall the percentage of patients enrolled in clinical trials is very low. The main reasons for lack of participation in clinical trials include insufficient medical personnel, the absence of a specifically dedicated research unit inside the medical oncology structures and in some cases lack of research

  16. A risk-based approach to cleanup: Problems and pitfalls

    SciTech Connect

    Anspaugh, L.

    1995-10-01

    This paper details information dealing with the meetings of the International Council of Scientific Unions (ICSU). Topics discussed include: Radtest program to summarize all data on radiation doses resulting from nuclear weapons testing; current status of US cleanup strategies; development of new milestones for the project due to reduced budgets; health hazards; and risk reduction.

  17. Learning to Teach with Two Mentors: Revisiting the "Two-Worlds Pitfall" in Student Teaching

    ERIC Educational Resources Information Center

    Smith, Emily R.; Avetisian, Virginia

    2011-01-01

    Research on learning to teach repeatedly cites the disjuncture in teaching practices promoted across universities and K-12 schools. Much of the literature that is focused on this "two-worlds pitfall" (Feiman-Nemser & Buchmann, 1985) describes the influence of cooperating teachers' more traditional teaching practices on teacher candidates'…

  18. Analysis of Factors Enhancing Pitfall in Research and Teaching of the Nigerian University System

    ERIC Educational Resources Information Center

    Ahmed, Tafida; Umar, Kasim; Paul, Chima

    2015-01-01

    The paper analyses factors enhancing pitfall in research and teaching in the Nigerian university system. Using data generated from secondary sources, it was found that so many factors are responsible for the constant decay in teaching and research in the Nigerian universities. The paper however found from literature that the high rate of pitfalls…

  19. The Pitfalls of Mobile Devices in Learning: A Different View and Implications for Pedagogical Design

    ERIC Educational Resources Information Center

    Ting, Yu-Liang

    2012-01-01

    Studies have been devoted to the design, implementation, and evaluation of mobile learning in practice. A common issue among students' responses toward this type of learning concerns the pitfalls of mobile devices, including small screen, limited input options, and low computational power. As a result, mobile devices are not always perceived by…

  20. Efficient sampling of ground-dwelling arthropods using pitfall traps in arid steppes.

    PubMed

    Cheli, Germán H; Corley, Juan C

    2010-01-01

    Pitfall trapping is probably the most frequently used method for sampling ground-dwelling arthropods. While the capture of specimens in pitfall traps largely depends on the number of individuals in the sampled area, trap design and trapping effort for a given environment, can also affect sampling success. The aim of this study was to determine the best pitfall trapping design for collecting ground-dwelling arthropods in the wind-blown and cold arid steppe areas of Patagonia. We tested four designs of traps, six types of preservative and different times of activation as well as the quantity of traps. Both preservation attributes and sampling efficiency differed between different trap designs and fluids compared. We conclude that in order to obtain reliable data on the structure of a community of ground-dwelling arthropods in Patagonia, at least three pitfall traps per experimental unit are required. In addition, traps should be opened for a minimum of 10 days filled with 300 ml of 30% ethylene glycol. We also suggested the use of a simple trap design (i. e. without funnel or roof). We believe these findings will contribute to more appropriate sampling of the ground dwelling fauna of Patagonia as well as other arid areas, leading to more reliable diversity studies. PMID:21271057

  1. Two new planthopper species (Hemiptera, Fulgoroidea, Caliscelidae) collected in pitfall traps in Zambia.

    PubMed

    Chmurova, Lucia; Webb, Michael D

    2016-01-01

    Two new species of planthoppers in the family Caliscelidae (Hemiptera: Fulgoroidea) are described from Zambia, i.e., Afronaso spinosa sp. n. and Calampocus zambiaensis sp. n. All specimens are flightless males and nearly all were collected from baited pitfall traps (except for one specimen collected from a yellow pan trap), suggesting that they live near to or on the ground. PMID:27615842

  2. Empathy and Social-Emotional Learning: Pitfalls and Touchstones for School-Based Programs

    ERIC Educational Resources Information Center

    Maxwell, Bruce; DesRoches, Sarah

    2010-01-01

    This chapter identifies three common pitfalls in the use of the concept of empathy in formal social-emotional learning interventions: (1) not distinguishing between affective and cognitive empathy ("equivocation"); (2) overestimating the role of the imagination in empathizing ("Piaget's fallacy"); and (3) not accommodating the developmental and…

  3. The Pitfalls of Valenced Labels and the Benefits of Properly Calibrated Psychological Flexibility

    ERIC Educational Resources Information Center

    McNulty, James K.; Fincham, Frank D.

    2012-01-01

    Replies to comments by Sonja Lyubomirsky (see record 2012-27130-008), Riva Guiseppe (see record 2012-27130-009), and Alan S. Waterman (see record 2012-27130-010) on the original article by McNulty and Fincham (see record 2011-15476-001) regarding the pitfalls of valenced labels and the benefits of properly calibrated psychological flexibility.

  4. Pitfalls and Promises: The Use of Secondary Data Analysis in Educational Research

    ERIC Educational Resources Information Center

    Smith, Emma

    2008-01-01

    This paper considers the use of secondary data analysis in educational research. It addresses some of the promises and potential pitfalls that influence its use and explores a possible role for the secondary analysis of numeric data in the "new" political arithmetic tradition of social research. Secondary data analysis is a relatively under-used…

  5. Benefits and Pitfalls: Simple Guidelines for the Use of Social Networking Tools in K-12 Education

    ERIC Educational Resources Information Center

    Huffman, Stephanie

    2013-01-01

    The article will outline a framework for the use of social networking tools in K-12 education framed around four thought provoking questions: 1) what are the benefits and pitfalls of using social networking tools in P-12 education, 2) how do we plan effectively for the use of social networking tool, 3) what role does professional development play…

  6. Rewards & pitfalls of using treating pressure analysis for evaluating fracture design

    SciTech Connect

    Cramer, D.D.

    1996-12-31

    Analyzing pressures during a fracture treatment provides insight into the hydraulic fracturing process, and is widely used today. In this paper, case histories are reviewed and guidelines are presented to identify pitfalls and establish strategies in pressure-analysis methods and procedures.

  7. 43 CFR 10010.35 - Methodology and scientific accuracy.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Methodology and scientific accuracy. 10010.35 Section 10010.35 Public Lands: Interior Regulations Relating to Public Lands (Continued) UTAH... ENVIRONMENTAL POLICY ACT Environmental Impact Statements § 10010.35 Methodology and scientific...

  8. 43 CFR 10010.35 - Methodology and scientific accuracy.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Methodology and scientific accuracy. 10010.35 Section 10010.35 Public Lands: Interior Regulations Relating to Public Lands (Continued) UTAH... ENVIRONMENTAL POLICY ACT Environmental Impact Statements § 10010.35 Methodology and scientific...

  9. 43 CFR 10010.35 - Methodology and scientific accuracy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Methodology and scientific accuracy. 10010.35 Section 10010.35 Public Lands: Interior Regulations Relating to Public Lands (Continued) UTAH... ENVIRONMENTAL POLICY ACT Environmental Impact Statements § 10010.35 Methodology and scientific...

  10. 43 CFR 10010.35 - Methodology and scientific accuracy.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Methodology and scientific accuracy. 10010.35 Section 10010.35 Public Lands: Interior Regulations Relating to Public Lands (Continued) UTAH... ENVIRONMENTAL POLICY ACT Environmental Impact Statements § 10010.35 Methodology and scientific...

  11. Scientific Directory 1977 and Annual Bibliography 1976.

    ERIC Educational Resources Information Center

    National Institutes of Health, (DHEW), Bethesda, MD. Div. of Scientific Reports.

    The Scientific Directory and Annual Bibliography of the National Institutes of Health (NIH) is intended for reference use by research workers in the biomedical sciences. It presents a broad outline of NIH organizational structure, the professional staff, and their scientific and technical publications covering work done at NIH. The volume also…

  12. Scientific Human Resources: Profiles and Issues.

    ERIC Educational Resources Information Center

    Falk, Charles E.

    This publication is a report in which past trends and events relative to scientific manpower in the form of scientists and engineers are reviewed, the current status of the scientific manpower situation is described, and various assessments of possible future situations are compared. Within the last 25 years the situation has changed from one in…

  13. Open Access and Civic Scientific Information Literacy

    ERIC Educational Resources Information Center

    Zuccala, Alesia

    2010-01-01

    Introduction: We examine how residents and citizens of The Netherlands perceive open access to acquire preliminary insight into the role it might play in cultivating civic scientific literacy. Open access refers to scientific or scholarly research literature available on the Web to scholars and the general public in free online journals and…

  14. Burn prevention mechanisms and outcomes: pitfalls, failures and successes.

    PubMed

    Atiyeh, Bishara S; Costagliola, Michel; Hayek, Shady N

    2009-03-01

    -risk groups. Depending on the population of the country, burns prevention could be a national programme. This can ensure sufficient funds are available and lead to proper coordination of district, regional, and tertiary care centres. It could also provide for compulsory reporting of all burn admissions to a central registry, and these data could be used to evaluate strategies and prevention programmes that should be directed at behavioural and environmental changes which can be easily adopted into lifestyle. Particularly in LMICs, the emphasis in burn prevention should be by advocating change from harmful cultural practices. This needs to be done with care and sensitivity. The present review is a summary of what has already been accomplished in terms of burn prevention highlighting some of the successes but above all the numerous pitfalls and failures. Recognizing these failures is the first step towards development of more effective burn prevention strategies particularly in LMICs in which burn injury remains endemic and associated with a high mortality rate. Burn prevention is not easy, but easy or not, we have no options; burns must be prevented. PMID:18926639

  15. Scientific Word Processors Proliferate.

    ERIC Educational Resources Information Center

    Analytical Chemistry, 1985

    1985-01-01

    Briefly describes most of the currently available scientific word processing software packages. Unless noted, these products (including Molecular Presentation Graphics, ProofWriter, Spellbinder Scientific, Volkswriter Scientific, and WordMARC) run on the IBM PC family of microcomputers. (JN)

  16. Dishonesty in scientific research.

    PubMed

    Mazar, Nina; Ariely, Dan

    2015-11-01

    Fraudulent business practices, such as those leading to the Enron scandal and the conviction of Bernard Madoff, evoke a strong sense of public outrage. But fraudulent or dishonest actions are not exclusive to the realm of big corporations or to evil individuals without consciences. Dishonest actions are all too prevalent in everyone's daily lives, because people are constantly encountering situations in which they can gain advantages by cutting corners. Whether it's adding a few dollars in value to the stolen items reported on an insurance claim form or dropping outlier data points from a figure to make a paper sound more interesting, dishonesty is part of the human condition. Here, we explore how people rationalize dishonesty, the implications for scientific research, and what can be done to foster a culture of research integrity. PMID:26524587

  17. Scientific Utopia: An agenda for improving scientific communication (Invited)

    NASA Astrophysics Data System (ADS)

    Nosek, B.

    2013-12-01

    The scientist's primary incentive is publication. In the present culture, open practices do not increase chances of publication, and they often require additional work. Practicing the abstract scientific values of openness and reproducibility thus requires behaviors in addition to those relevant for the primary, concrete rewards. When in conflict, concrete rewards are likely to dominate over abstract ones. As a consequence, the reward structure for scientists does not encourage openness and reproducibility. This can be changed by nudging incentives to align scientific practices with scientific values. Science will benefit by creating and connecting technologies that nudge incentives while supporting and improving the scientific workflow. For example, it should be as easy to search the research literature for my topic as it is to search the Internet to find hilarious videos of cats falling off of furniture. I will introduce the Center for Open Science (http://centerforopenscience.org/) and efforts to improve openness and reproducibility such as http://openscienceframework.org/. There will be no cats.

  18. Temperature effects on pitfall catches of epigeal arthropods: a model and method for bias correction.

    PubMed

    Saska, Pavel; van der Werf, Wopke; Hemerik, Lia; Luff, Martin L; Hatten, Timothy D; Honek, Alois; Pocock, Michael

    2013-02-01

    Carabids and other epigeal arthropods make important contributions to biodiversity, food webs and biocontrol of invertebrate pests and weeds. Pitfall trapping is widely used for sampling carabid populations, but this technique yields biased estimates of abundance ('activity-density') because individual activity - which is affected by climatic factors - affects the rate of catch. To date, the impact of temperature on pitfall catches, while suspected to be large, has not been quantified, and no method is available to account for it. This lack of knowledge and the unavailability of a method for bias correction affect the confidence that can be placed on results of ecological field studies based on pitfall data.Here, we develop a simple model for the effect of temperature, assuming a constant proportional change in the rate of catch per °C change in temperature, r, consistent with an exponential Q10 response to temperature. We fit this model to 38 time series of pitfall catches and accompanying temperature records from the literature, using first differences and other detrending methods to account for seasonality. We use meta-analysis to assess consistency of the estimated parameter r among studies.The mean rate of increase in total catch across data sets was 0·0863 ± 0·0058 per °C of maximum temperature and 0·0497 ± 0·0107 per °C of minimum temperature. Multiple regression analyses of 19 data sets showed that temperature is the key climatic variable affecting total catch. Relationships between temperature and catch were also identified at species level. Correction for temperature bias had substantial effects on seasonal trends of carabid catches.Synthesis and Applications. The effect of temperature on pitfall catches is shown here to be substantial and worthy of consideration when interpreting results of pitfall trapping. The exponential model can be used both for effect estimation and for bias correction of observed data. Correcting for temperature

  19. The pitfalls of bioterrorism preparedness: the anthrax and smallpox experiences.

    PubMed

    Cohen, Hillel W; Gould, Robert M; Sidel, Victor W

    2004-10-01

    Bioterrorism preparedness programs have contributed to death, illness, and waste of public health resources without evidence of benefit. Several deaths and many serious illnesses have resulted from the smallpox vaccination program; yet there is no clear evidence that a threat of smallpox exposure ever existed. The anthrax spores released in 2001 have been linked to secret US military laboratories-the resultant illnesses and deaths might not have occurred if those laboratories were not in operation. The present expansion of bioterrorism preparedness programs will continue to squander health resources, increase the dangers of accidental or purposeful release of dangerous pathogens, and further undermine efforts to enforce international treaties to ban biological and chemical weapons. The public health community should acknowledge the substantial harm that bioterrorism preparedness has already caused and develop mechanisms to increase our public health resources and to allocate them to address the world's real health needs. PMID:15451727

  20. Immune biomarkers: the promises and pitfalls of personalized medicine.

    PubMed

    Willis, Joanna C D; Lord, Graham M

    2015-05-01

    Substantial progress in molecular immunology, coupled with an increasing focus on translational research and an enthusiasm for personalized medicine, has resulted in a rapid expansion in the field of immune biomarkers in recent years. In this Science and Society article, we provide a conceptual overview of the field and discuss the progress that has been made so far, as well as the future potential in the context of the scientific, logistical, financial, legal and ethical framework within which this research is being carried out and translated into clinical use. PMID:25814400