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Sample records for sex combs asx

  1. A Logical OR Redundancy Within the Asx-Pro-Asx-Gly Type I beta-Turn Motif

    SciTech Connect

    Lee,J.; Dubey, V.; Longo, L.; Blaber, M.

    2008-01-01

    Turn secondary structure is essential to the formation of globular protein architecture. Turn structures are, however, much more complex than either ?-helix or ?-sheet, and the thermodynamics and folding kinetics are poorly understood. Type I ?-turns are the most common type of reverse turn, and they exhibit a statistical consensus sequence of Asx-Pro-Asx-Gly (where Asx is Asp or Asn). A comprehensive series of individual and combined Asx mutations has been constructed within three separate type I 3:5 G1 bulge ?-turns in human fibroblast growth factor-1, and their effects on structure, stability, and folding have been determined. The results show a fundamental logical OR relationship between the Asx residues in the motif, involving H-bond interactions with main-chain amides within the turn. These interactions can be modulated by additional interactions with residues adjacent to the turn at positions i + 4 and i + 6. The results show that the Asx residues in the turn motif make a substantial contribution to the overall stability of the protein, and the Asx logical OR relationship defines a redundant system that can compensate for deleterious point mutations. The results also show that the stability of the turn is unlikely to be the prime determinant of formation of turn structure in the folding transition state.

  2. A Logical OR Redundancy within the Asx-Pro-Asx-Gly Type 1 {Beta}-Turn Motif

    SciTech Connect

    Lee, Jihun; Dubey, Vikash Kumar; Longo, Lian M.; Blaber, Michael

    2008-04-19

    Turn secondary structure is essential to the formation of globular protein architecture. Turn structures are, however, much more complex than either {alpha}-helix or {beta}-sheet, and the thermodynamics and folding kinetics are poorly understood. Type I {beta}-turns are the most common type of reverse turn, and they exhibit a statistical consensus sequence of Asx-Pro-Asx-Gly (where Asx is Asp or Asn). A comprehensive series of individual and combined Asx mutations has been constructed within three separate type I 3:5 G1 bulge {beta}-turns in human fibroblast growth factor-1, and their effects on structure, stability, and folding have been determined. The results show a fundamental logical OR relationship between the Asx residues in the motif, involving H-bond interactions with main-chain amides within the turn. These interactions can be modulated by additional interactions with residues adjacent to the turn at positions i + 4 and i + 6. The results show that the Asx residues in the turn motif make a substantial contribution to the overall stability of the protein, and the Asx logical OR relationship defines a redundant system that can compensate for deleterious point mutations. The results also show that the stability of the turn is unlikely to be the prime determinant of formation of turn structure in the folding transition state.

  3. The Homeotic Gene Sex Combs Reduced of Drosophila Melanogaster Is Differentially Regulated in the Embryonic and Imaginal Stages of Development

    PubMed Central

    Pattatucci, A. M.; Kaufman, T. C.

    1991-01-01

    The Sex combs reduced (Scr) locus is unique among the genes contained within the Antennapedia complex (ANT-C) of Drosophila melanogaster in that it directs functions that are required for both cephalic and thoracic development in the embryo and the adult. Antibodies raised against protein encoded by Scr were used to follow the distribution of this gene product in embryos and imaginal discs of third instar larvae. Analysis of Scr protein accumulation in embryos hemizygous for breakpoint lesions mapping throughout the locus has allowed us to determine that sequences required for establishment of the Scr embryonic pattern are contained within a region of DNA that overlaps with the identified upstream regulatory region of the segmentation gene fushi tarazu (ftz). Gain-of-function mutations in Scr result in the presence of ectopic sex comb teeth on the first tarsal segment of mesothoracic and metathoracic legs of adult males. Heterozygous combinations of gain-of-function alleles with a wild-type Scr gene exhibit no evidence of ectopic protein localization in the second and third thoracic segments of embryos. However, mesothoracic and metathoracic leg imaginal discs can be shown to accumulate ectopically expressed Scr protein, implying a differential regulation of the Scr gene during these two periods of development. Additionally, we have found that the spatial pattern of Scr gene expression in imaginal tissues involved in the development of the adult thorax is governed in part by synapsis of homologous chromosomes in this region of the ANT-C. However, those imaginal discs that arise anteriorly to the prothorax do not appear to be sensitive to this form of gene regulation. Finally, we have demonstrated that the extent of Scr expression is influenced by mutations at the Polycomb (Pc) locus but not by mutant alleles of the zeste (z) gene. Taken together, our data suggests that Scr gene expression is differentially regulated both temporally and spatially in a manner that is

  4. Distinct self-interaction domains promote Multi Sex Combs accumulation in and formation of the Drosophila histone locus body

    PubMed Central

    Terzo, Esteban A.; Lyons, Shawn M.; Poulton, John S.; Temple, Brenda R. S.; Marzluff, William F.; Duronio, Robert J.

    2015-01-01

    Nuclear bodies (NBs) are structures that concentrate proteins, RNAs, and ribonucleoproteins that perform functions essential to gene expression. How NBs assemble is not well understood. We studied the Drosophila histone locus body (HLB), a NB that concentrates factors required for histone mRNA biosynthesis at the replication-dependent histone gene locus. We coupled biochemical analysis with confocal imaging of both fixed and live tissues to demonstrate that the Drosophila Multi Sex Combs (Mxc) protein contains multiple domains necessary for HLB assembly. An important feature of this assembly process is the self-interaction of Mxc via two conserved N-terminal domains: a LisH domain and a novel self-interaction facilitator (SIF) domain immediately downstream of the LisH domain. Molecular modeling suggests that the LisH and SIF domains directly interact, and mutation of either the LisH or the SIF domain severely impairs Mxc function in vivo, resulting in reduced histone mRNA accumulation. A region of Mxc between amino acids 721 and 1481 is also necessary for HLB assembly independent of the LisH and SIF domains. Finally, the C-terminal 195 amino acids of Mxc are required for recruiting FLASH, an essential histone mRNA-processing factor, to the HLB. We conclude that multiple domains of the Mxc protein promote HLB assembly in order to concentrate factors required for histone mRNA biosynthesis. PMID:25694448

  5. Inhibition of chromatin remodeling by Polycomb Group protein Posterior Sex Combs is mechanistically distinct from nucleosome binding1

    PubMed Central

    Lo, Stanley M.; Francis, Nicole J.

    2010-01-01

    Polycomb Group (PcG) proteins are essential regulators of development that maintain gene silencing in Drosophila and mammals through alterations of chromatin structure. One key PcG protein, Posterior Sex Combs (PSC), is part of at least two complexes: Polycomb Repressive Complex 1 (PRC1) and dRING Associated Factors (dRAF). PRC1-class complexes compact chromatin and inhibit chromatin remodeling, while dRAF has E3 ligase activity for ubiquitylation of histone H2A; activities of both complexes can inhibit transcription. The noncovalent effects of PRC1-class complexes on chromatin can be recapitulated by PSC alone, and the region of PSC required for these activities is essential for PSC function in vivo. To understand how PSC interacts with chromatin to exert its repressive effects, we compared the ability of PSC to bind to and inhibit remodeling of various nucleosomal templates, and determined which regions of PSC are required for mononucleosome binding and inhibition of chromatin remodeling. We find that PSC binds mononucleosome templates but inhibits their remodeling poorly. Addition of linker DNA to mononucleosomes allows their remodeling to be inhibited, although higher concentrations of PSC are required than for inhibition of multi-nucleosome templates. The C-terminal region of PSC (aa 456-1603) is important for inhibition of chromatin remodeling, and we identified aa 456-909 as sufficient for stable nucleosome binding but not for inhibition of chromatin remodeling. Our data suggest distinct mechanistic steps between nucleosome binding and inhibition of chromatin remodeling. PMID:20873869

  6. Sex comb on midleg (Scm) is a functional link between PcG-repressive complexes in Drosophila

    PubMed Central

    Kang, Hyuckjoon; McElroy, Kyle A.; Jung, Youngsook Lucy; Alekseyenko, Artyom A.; Zee, Barry M.; Park, Peter J.

    2015-01-01

    The Polycomb group (PcG) proteins are key regulators of development in Drosophila and are strongly implicated in human health and disease. How PcG complexes form repressive chromatin domains remains unclear. Using cross-linked affinity purifications of BioTAP-Polycomb (Pc) or BioTAP-Enhancer of zeste [E(z)], we captured all PcG-repressive complex 1 (PRC1) or PRC2 core components and Sex comb on midleg (Scm) as the only protein strongly enriched with both complexes. Although previously not linked to PRC2, we confirmed direct binding of Scm and PRC2 using recombinant protein expression and colocalization of Scm with PRC1, PRC2, and H3K27me3 in embryos and cultured cells using ChIP-seq (chromatin immunoprecipitation [ChIP] combined with deep sequencing). Furthermore, we found that RNAi knockdown of Scm and overexpression of the dominant-negative Scm-SAM (sterile α motif) domain both affected the binding pattern of E(z) on polytene chromosomes. Aberrant localization of the Scm-SAM domain in long contiguous regions on polytene chromosomes revealed its independent ability to spread on chromatin, consistent with its previously described ability to oligomerize in vitro. Pull-downs of BioTAP-Scm captured PRC1 and PRC2 and additional repressive complexes, including PhoRC, LINT, and CtBP. We propose that Scm is a key mediator connecting PRC1, PRC2, and transcriptional silencing. Combined with previous structural and genetic analyses, our results strongly suggest that Scm coordinates PcG complexes and polymerizes to produce broad domains of PcG silencing. PMID:26063573

  7. The gap gene Krüppel of Rhodnius prolixus is required for segmentation and for repression of the homeotic gene sex comb-reduced.

    PubMed

    Lavore, Andrés; Esponda-Behrens, Natalia; Pagola, Lucía; Rivera-Pomar, Rolando

    2014-03-01

    The establishment of the anterior-posterior segmentation in insects requires the concerted action of a hierarchical gene network. Here, we study the orthologue of Krüppel gap gene in the hemipteran Rhodnius prolixus (Rp-Kr). We characterized its structure, expression pattern and function. The genomic sequence upstream of the Rp-Kr transcriptional unit shows a putative regulatory region conserved in the orthologue genes from Drosophila melanogaster and Tribolium castaneum. Rp-Kr expression is zygotic and it is expressed in the anterior half of the embryo (the posterior half of the egg) during the blastoderm stage and germ band formation; later, during germ band extension, it is expressed in a central domain, from T2 to A3. The Rp-Kr loss of function phenotypes shows disrupted thoracic and abdominal segmentation. Embryos with weak segmentation phenotypes show homeotic transformations, in which an ectopic tibial comb, typical of T1 leg, appears in T2, which correlates with the ectopic expression of Rp-sex-comb reduced in this leg. PMID:24406318

  8. Frequency Combs

    NASA Astrophysics Data System (ADS)

    Hänsch, Theodor W.; Picqué, Nathalie

    Much of modern research in the field of atomic, molecular, and optical science relies on lasers, which were invented some 50 years ago and perfected in five decades of intense research and development. Today, lasers and photonic technologies impact most fields of science and they have become indispensible in our daily lives. Laser frequency combs were conceived a decade ago as tools for the precision spectroscopy of atomic hydrogen. Through the development of optical frequency comb techniques, technique a setup of the size 1 ×1 m2, good for precision measurements of any frequency, and even commercially available, has replaced the elaborate previous frequency-chain schemes for optical frequency measurements, which only worked for selected frequencies. A true revolution in optical frequency measurements has occurred, paving the way for the creation of all-optical clocks clock with a precision that might approach 10-18. A decade later, frequency combs are now common equipment in all frequency metrology-oriented laboratories. They are also becoming enabling tools for an increasing number of applications, from the calibration of astronomical spectrographs to molecular spectroscopy. This chapter first describes the principle of an optical frequency comb synthesizer. Some of the key technologies to generate such a frequency comb are then presented. Finally, a non-exhaustive overview of the growing applications is given.

  9. Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc)

    PubMed Central

    Sinclair, Donald A. R.; Syrzycka, Monika; Macauley, Matthew S.; Rastgardani, Tara; Komljenovic, Ivana; Vocadlo, David J.; Brock, Hugh W.; Honda, Barry M.

    2009-01-01

    O-linked N-acetylglucosamine transferase (OGT) reversibly modifies serine and threonine residues of many intracellular proteins with a single β-O-linked N-acetylglucosamine residue (O-GlcNAc), and has been implicated in insulin signaling, neurodegenerative disease, cellular stress response, and other important processes in mammals. OGT also glycosylates RNA polymerase II and various transcription factors, which suggests that it might be directly involved in transcriptional regulation. We report here that the Drosophila OGT is encoded by the Polycomb group (PcG) gene, super sex combs (sxc). Furthermore, major sites of O-GlcNAc modification on polytene chromosomes correspond to PcG protein binding sites. Our results thus suggest a direct role for O-linked glycosylation by OGT in PcG-mediated epigenetic gene silencing, which is important in developmental regulation, stem cell maintenance, genomic imprinting, and cancer. In addition, we observe rescue of sxc lethality by a human Ogt cDNA transgene; thus Drosophila may provide an ideal model to study important functional roles of OGT in mammals. PMID:19666537

  10. Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc).

    PubMed

    Sinclair, Donald A R; Syrzycka, Monika; Macauley, Matthew S; Rastgardani, Tara; Komljenovic, Ivana; Vocadlo, David J; Brock, Hugh W; Honda, Barry M

    2009-08-11

    O-linked N-acetylglucosamine transferase (OGT) reversibly modifies serine and threonine residues of many intracellular proteins with a single beta-O-linked N-acetylglucosamine residue (O-GlcNAc), and has been implicated in insulin signaling, neurodegenerative disease, cellular stress response, and other important processes in mammals. OGT also glycosylates RNA polymerase II and various transcription factors, which suggests that it might be directly involved in transcriptional regulation. We report here that the Drosophila OGT is encoded by the Polycomb group (PcG) gene, super sex combs (sxc). Furthermore, major sites of O-GlcNAc modification on polytene chromosomes correspond to PcG protein binding sites. Our results thus suggest a direct role for O-linked glycosylation by OGT in PcG-mediated epigenetic gene silencing, which is important in developmental regulation, stem cell maintenance, genomic imprinting, and cancer. In addition, we observe rescue of sxc lethality by a human Ogt cDNA transgene; thus Drosophila may provide an ideal model to study important functional roles of OGT in mammals. PMID:19666537

  11. Molecular Genetics of the Posterior Sex Combs/Suppressor 2 of Zeste Region of Drosophila: Aberrant Expression of the Suppressor 2 of Zeste Gene Results in Abnormal Bristle Development

    PubMed Central

    Brunk, B. P.; Martin, E. C.; Adler, P. N.

    1991-01-01

    We report the molecular characterization of the Posterior sex combs-Suppressor 2 of zeste region of Drosophila melanogaster. The distal breakpoint of the Aristapedioid inversion divides the region into two parts. We have molecularly mapped the lesions associated with several loss of function mutations in the Polycomb group gene Posterior sex combs (Psc) proximal to this breakpoint. In addition, we have found that lesions associated with several loss of function mutations in the Suppressor 2 of zeste [Su(z)2] gene lie distal to this breakpoint. Since the breakpoint does not cause a loss of function in either gene, no essential sequences are shared by these two neighboring genes. There are three dominant gain of function mutations in the region that result in abnormal bristle development. We find that all three juxtapose foreign DNA sequences upstream of the Su(z)2 gene, and that at least two of these mutations (Arp(1) and vg(D)) behave genetically as gain of function mutations in Su(z)2. Northern and in situ hybridization analyses show that the mutations result in increased accumulation of the Su(z)2 mRNA, which we argue is responsible for the bristle loss phenotype. PMID:1905661

  12. Modeling Frequency Comb Sources

    NASA Astrophysics Data System (ADS)

    Li, Feng; Yuan, Jinhui; Kang, Zhe; Li, Qian; Wai, P. K. A.

    2016-06-01

    Frequency comb sources have revolutionized metrology and spectroscopy and found applications in many fields. Stable, low-cost, high-quality frequency comb sources are important to these applications. Modeling of the frequency comb sources will help the understanding of the operation mechanism and optimization of the design of such sources. In this paper,we review the theoretical models used and recent progress of the modeling of frequency comb sources.

  13. Compact electrostatic comb actuator

    DOEpatents

    Rodgers, M. Steven; Burg, Michael S.; Jensen, Brian D.; Miller, Samuel L.; Barnes, Stephen M.

    2000-01-01

    A compact electrostatic comb actuator is disclosed for microelectromechanical (MEM) applications. The actuator is based upon a plurality of meshed electrostatic combs, some of which are stationary and others of which are moveable. One or more restoring springs are fabricated within an outline of the electrostatic combs (i.e. superposed with the moveable electrostatic combs) to considerably reduce the space required for the actuator. Additionally, a truss structure is provided to support the moveable electrostatic combs and prevent bending or distortion of these combs due to unbalanced electrostatic forces or external loading. The truss structure formed about the moveable electrostatic combs allows the spacing between the interdigitated fingers of the combs to be reduced to about one micron or less, thereby substantially increasing the number of active fingers which can be provided in a given area. Finally, electrostatic shields can be used in the actuator to substantially reduce unwanted electrostatic fields to further improve performance of the device. As a result, the compact electrostatic comb actuator of the present invention occupies only a fraction of the space required for conventional electrostatic comb actuators, while providing a substantial increase in the available drive force (up to one-hundred times).

  14. The optical spectrum of ternary alloy BBi1‑xAsx

    NASA Astrophysics Data System (ADS)

    Yalcin, Battal G.; Aslan, M.; Ozcan, M. H.; Rahnamaye Aliabad, H. A.

    2016-06-01

    Among the III–V semiconductors, boron BBi and BAs as well as their alloys have attracted both scientific and technological interest in recent years. We present a calculation of the structural, electronic and optical properties of ternary alloy BBi1‑xAsx by means of the WIEN2k software package. The exchange–correlation potential is treated by the generalized gradient approximation (GGA) within the schema of Wu and Cohen. Also, we have used the modified Becke–Johnson (mBJ) formalism to improve the band gap results. All the calculations have been performed after geometry optimization. In this study, we have investigated structural properties such as the lattice constant (a0), bulk modulus (B0) and its pressure derivative (B‧), and calculated the electronic band structures of the studied materials. Accurate calculation of linear optical properties, such as real (ε 1) and imaginary (ε 2) dielectric functions, reflectivity (R), electron energy loss spectrum, absorption coefficient (α), refractive index (n) and sum rule (Neff) are investigated. Our obtained results for studied binary compounds, BBi and BAs, fairly coincide with other theoretical calculations and experimental measurements. According to the best of our knowledge, no experimental or theoretical data are presently available for the studied ternary alloy BBi1‑xAsx (0 < x < 1). The role of electronic band structure calculation with regards to the linear optical properties of BBi1‑xAsx is discussed. The effect of the spin–orbit interaction (SOI) is also investigated and found to be quite small.

  15. Comb and brush acne.

    PubMed

    Petrozzi, J W

    1980-12-01

    Frequent combing or brushing of the hair may result in an exacerbation of existing acne or be the cause of localized acne. Because of today's hair styling habits and methods, this type of acne is commonly encountered but poorly appreciated by physicians. Patient education is the most important factor in the management of this condition. Comb and brush acne is another external factor to be added to the list of causes of "acne mechanica." PMID:6449356

  16. Butelase 1 is an Asx-specific ligase enabling peptide macrocyclization and synthesis.

    PubMed

    Nguyen, Giang K T; Wang, Shujing; Qiu, Yibo; Hemu, Xinya; Lian, Yilong; Tam, James P

    2014-09-01

    Proteases are ubiquitous in nature, whereas naturally occurring peptide ligases, enzymes catalyzing the reverse reactions of proteases, are rare occurrences. Here we describe the discovery of butelase 1, to our knowledge the first asparagine/aspartate (Asx) peptide ligase to be reported. This highly efficient enzyme was isolated from Clitoria ternatea, a cyclic peptide-producing medicinal plant. Butelase 1 shares 71% sequence identity and the same catalytic triad with legumain proteases but does not hydrolyze the protease substrate of legumain. Instead, butelase 1 cyclizes various peptides of plant and animal origin with yields greater than 95%. With Kcat values of up to 17 s(-1) and catalytic efficiencies as high as 542,000 M(-1) s(-1), butelase 1 is the fastest peptide ligase known. Notably, butelase 1 also displays broad specificity for the N-terminal amino acids of the peptide substrate, thus providing a new tool for C terminus-specific intermolecular peptide ligations. PMID:25038786

  17. Dynamics of comb-of-comb networks

    NASA Astrophysics Data System (ADS)

    Liu, Hongxiao; Lin, Yuan; Dolgushev, Maxim; Zhang, Zhongzhi

    2016-03-01

    The dynamics of complex networks, a current hot topic in many scientific fields, is often coded through the corresponding Laplacian matrix. The spectrum of this matrix carries the main features of the networks' dynamics. Here we consider the deterministic networks which can be viewed as "comb-of-comb" iterative structures. For their Laplacian spectra we find analytical equations involving Chebyshev polynomials whose properties allow one to analyze the spectra in deep. Here, in particular, we find that in the infinite size limit the corresponding spectral dimension goes as ds→2 . The ds leaves its fingerprint on many dynamical processes, as we exemplarily show by considering the dynamical properties of polymer networks, including single monomer displacement under a constant force, mechanical relaxation, and fluorescence depolarization.

  18. Tellurium n-type doping of highly mismatched amorphous GaN1-xAsx alloys in plasma-assisted molecular beam epitaxy

    DOE PAGESBeta

    Novikov, S. V.; Ting, M.; Yu, K. M.; Sarney, W. L.; Martin, R. W.; Svensson, S. P.; Walukiewicz, W.; Foxon, C. T.

    2014-10-01

    In this paper we report our study on n-type Te doping of amorphous GaN1-xAsx layers grown by plasma-assisted molecular beam epitaxy. We have used a low temperature PbTe source as a source of tellurium. Reproducible and uniform tellurium incorporation in amorphous GaN1-xAsx layers has been successfully achieved with a maximum Te concentration of 9×10²⁰ cm⁻³. Tellurium incorporation resulted in n-doping of GaN1-xAsx layers with Hall carrier concentrations up to 3×10¹⁹ cm⁻³ and mobilities of ~1 cm²/V s. The optimal growth temperature window for efficient Te doping of the amorphous GaN1-xAsx layers has been determined.

  19. Tellurium n-type doping of highly mismatched amorphous GaN1-xAsx alloys in plasma-assisted molecular beam epitaxy

    NASA Astrophysics Data System (ADS)

    Novikov, S. V.; Ting, M.; Yu, K. M.; Sarney, W. L.; Martin, R. W.; Svensson, S. P.; Walukiewicz, W.; Foxon, C. T.

    2014-10-01

    In this paper we report our study on n-type Te doping of amorphous GaN1-xAsx layers grown by plasma-assisted molecular beam epitaxy. We have used a low temperature PbTe source as a source of tellurium. Reproducible and uniform tellurium incorporation in amorphous GaN1-xAsx layers has been successfully achieved with a maximum Te concentration of 9×1020 cm-3. Tellurium incorporation resulted in n-doping of GaN1-xAsx layers with Hall carrier concentrations up to 3×1019 cm-3 and mobilities of ~1 cm2/V s. The optimal growth temperature window for efficient Te doping of the amorphous GaN1-xAsx layers has been determined.

  20. Optical frequency comb spectroscopy.

    PubMed

    Foltynowicz, A; Masłowski, P; Ban, T; Adler, F; Cossel, K C; Briles, T C; Ye, J

    2011-01-01

    Optical frequency combs offer enormous potential in the detection and control of atoms and molecules by combining their vast spectral coverage with the extremely high spectral resolution of each individual comb component. Sensitive and multiplexed trace gas detection via cavity-enhanced direct frequency comb spectroscopy has been demonstrated for various molecules and applications; however, previous demonstrations have been confined to the visible and near-infrared wavelength range. Future spectroscopic capabilities are created by developing comb sources and spectrometers for the deep ultraviolet and mid-infrared spectral regions. Here we present a broadband high resolution mid-infrared frequency comb-based Fourier transform spectrometer operating in the important molecular fingerprint spectral region of 2100-3600 cm(-1) (2.8-4.8 microm). The spectrometer, employing a multipass cell, allows simultaneous acquisition of broadband, high resolution spectra (down to 0.0035 cm(-1) of many molecular species at concentrations in the part-per-billion range in less than 1 min acquisition time. The system enables precise measurements of concentration even in gas mixtures that exhibit continuous absorption bands. The current sensitivity, 2 x 10(-8) cm(-1) Hz-1/2 per spectral element, is expected to improve by two orders of magnitude with an external enhancement cavity. We have demonstrated this sensitivity increase by combining cavity-enhanced frequency comb spectroscopy with a scanning Fourier transform spectrometer in the near-infrared region and achieving a sensitivity of 4.7 x 10(-10) cm(-1) Hz(-1/2). A cavity-enhanced mid-infrared comb spectrometer will provide a near real-time, high sensitivity, high resolution, precisely frequency calibrated, broad bandwidth system for many applications. PMID:22457942

  1. Microwave Comb Generator

    NASA Technical Reports Server (NTRS)

    Sigman, E. H.

    1989-01-01

    Stable reference tones aid testing and calibration of microwave receivers. Signal generator puts out stable tones in frequency range of 2 to 10 GHz at all multiples of reference input frequency, at any frequency up to 1 MHz. Called "comb generator" because spectral plot resembles comb. DC reverse-bias current switched on and off at 1 MHz to generate sharp pulses in step-recovery diode. Microwave components mounted on back of special connector containing built-in attenuator. Used in testing microwave and spread-spectrum wide-band receivers.

  2. Coarse frequency comb interferometry

    NASA Astrophysics Data System (ADS)

    Schwider, J.

    2008-08-01

    Real wedge interferometers of the Fizeau-type do not allow for fringes in case of a spectral broad band source - or in short: for white light fringes. Here, the use of a suitable frequency comb source will help to overcome this limitation on the one hand and on the other will offer the capability for enhanced phase sensitivity in high precision measurements of surface deviations. Frequency combs can be produced either by using a pulse train from a fs-laser or by passive filtering of the light emitted by a broad band source as a superlum-diode or a fs-laser. The frequency comb produced by a common fs-laser is extremely fine, i.e., the frequency difference of consecutive peaks is very small or the distance of consecutive pulses of the pulse train might be of the order of 1m. Therefore, the coarse pulse train produced by passive filtering of a broad band source is better adapted to the needs of surface testing interferometers. White light fringes are either applied for the profiling of discontinuous surfaces and/or can serve as an indication for the correct choice of multiplication factors in superposition interferometry. During the last decennium it became more and more clear that spatially incoherent sources provide better measuring accuracy in surface measurements due to the reduced influence of dust diffraction patterns. The advantage of laser illumination can nevertheless be maintained if the laser light is made spatially incoherent through moving scatterers in the light path. Here, we will discuss the application of spatially incoherent broad band light frequency filtered through a Fabry-Perot filter. The main applications are in the following fields: (1) surface profiling applications using two-beam Fizeau interferometers, (2) selection of single cavities out of a series of interlaced cavities, and (3) sensitivity enhancement for multi-beam interferometers for planeness or sphericity measurements. Some of the discussed possibilities will be experimentally

  3. Laser Spectroscopy and Frequency Combs

    NASA Astrophysics Data System (ADS)

    Hänsch, Theodor W.; Picqué, Nathalie

    2013-12-01

    The spectrum of a frequency comb, commonly generated by a mode-locked femtosecond laser consists of several hundred thousand precisely evenly spaced spectral lines. Such laser frequency combs have revolutionized the art measuring the frequency of light, and they provide the long-missing clockwork for optical atomic clocks. The invention of the frequency comb technique has been motivated by precision laser spectroscopy of the simple hydrogen atom. The availability of commercial instruments is facilitating the evolution of new applications far beyond the original purpose. Laser combs are becoming powerful instruments for broadband molecular spectroscopy by dramatically improving the resolution and recording speed of Fourier spectrometers and by creating new opportunities for highly multiplexed nonlinear spectroscopy, such as two-photon spectroscopy or coherent Raman spectroscopy. Other emerging applications of frequency combs range from fundamental research in astronomy, chemistry, or attosecond science to telecommunications and satellite navigation.

  4. Molecular Comb Development

    SciTech Connect

    Ferrell, T.L.; Thundat, G.T.; Witkowski, C.E., III

    2007-07-17

    This CRADA was developed to enable ORNL to assist Protein Discovery, Inc. to develop a novel biomolecular separation system based on an ORNL patent application 'Photoelectrochemical Molecular Comb' by Thundat, Ferrell, and Brown. The Molecular Comb concept is based on creating light-induced charge carriers at a semiconductor-liquid interface, which is kept at a potential control such that a depletion layer is formed in the semiconductor. Focusing light from a low-power illumination source creates electron-hole pairs, which get separated in the depletion layer. The light-induced charge carriers reaching the surface attract oppositely charged biomolecules present in the solution. The solution is a buffer solution with very small concentrations of biomolecules. As the focused light is moved across the surface of the semiconductor-liquid interface, the accumulated biomolecules follow the light beam. A thin layer of gel or other similar material on the surface of the semiconductor can act as a sieving medium for separating the biomolecules according to their sizes.

  5. Quantum spin Hall insulators in functionalized arsenene (AsX, X = F, OH and CH3) monolayers with pronounced light absorption.

    PubMed

    Zhao, Jun; Li, Yanle; Ma, Jing

    2016-05-14

    The search for new two-dimensional topological insulators (2D-TIs) with large band gaps is of great interest and importance. Our first-principles calculations predicted three candidates for 2D-TIs, arsenene functionalized with F, OH and CH3 groups (AsX, X = F, OH and CH3), which preserved large bulk band gaps from 100 to 160 meV (up to 260 meV) derived from the spin-orbit coupling (SOC) within the px,y orbitals. This picture is similar to what was reported for an AsH monolayer with a band gap of 193 meV. Ab initio molecular dynamic (AIMD) simulations demonstrated the thermal stabilities of the AsX monolayers even at 500 K. The nontrivial topological phase was confirmed by the topological invariant Z2 and topological edge state. The topological electronic bandgap of the AsF monolayer can be effectively modulated by biaxial tensile strain and vertical external electric field. In addition, pronounced light absorption in the near-infrared and visible range of the solar spectrum was expected for the AsX (X = H, F) monolayers from the adsorption peaks at 0.45-1.6 eV, which is attractive for light harvesting. The nontrivial quantum spin Hall (QSH) insulators AsX could be promising candidates for practical room-temperature applications in dissipationless transport devices and photovoltaics. PMID:27101795

  6. Mid-infrared frequency combs

    NASA Astrophysics Data System (ADS)

    Schliesser, Albert; Picqué, Nathalie; Hänsch, Theodor W.

    2012-07-01

    Laser frequency combs are coherent light sources that emit a broad spectrum of discrete, evenly spaced narrow lines whose absolute frequency can be measured to within the accuracy of an atomic clock. Their development in the near-infrared and visible domains has revolutionized frequency metrology while also providing numerous unexpected opportunities in other fields such as astronomy and attosecond science. Researchers are now exploring how to extend frequency comb techniques to the mid-infrared spectral region. Versatile mid-infrared frequency comb generators based on novel laser gain media, nonlinear frequency conversion or microresonators promise to significantly expand the applications of frequency combs. In particular, novel approaches to molecular spectroscopy in the 'fingerprint region', with dramatically improved precision, sensitivity, recording time and/or spectral bandwidth may lead to new discoveries in the various fields relevant to molecular science.

  7. Quantum Cascade Laser Frequency Combs

    NASA Astrophysics Data System (ADS)

    Faist, Jérôme; Villares, Gustavo; Scalari, Giacomo; Rösch, Markus; Bonzon, Christopher; Hugi, Andreas; Beck, Mattias

    2016-06-01

    It was recently demonstrated that broadband quantum cascade lasers can operate as frequency combs. As such, they operate under direct electrical pumping at both mid-infrared and THz frequencies, making them very attractive for dual-comb spectroscopy. Performance levels are continuously improving, with average powers over 100mW and frequency coverage of 100 cm-1 in the mid-infrared region. In the THz range, 10mW of average power and 600 GHz of frequency coverage are reported. As a result of the very short upper state lifetime of the gain medium, the mode proliferation in these sources arises from four-wave mixing rather than saturable absorption. As a result, their optical output is characterized by the tendency of small intensity modulation of the output power, and the relative phases of the modes to be similar to the ones of a frequency modulated laser. Recent results include the proof of comb operation down to a metrological level, the observation of a Schawlow-Townes broadened linewidth, as well as the first dual-comb spectroscopy measurements. The capability of the structure to integrate monothically nonlinear optical elements as well as to operate as a detector shows great promise for future chip integration of dual-comb systems.

  8. Quantum spin Hall insulators in functionalized arsenene (AsX, X = F, OH and CH3) monolayers with pronounced light absorption

    NASA Astrophysics Data System (ADS)

    Zhao, Jun; Li, Yanle; Ma, Jing

    2016-05-01

    The search for new two-dimensional topological insulators (2D-TIs) with large band gaps is of great interest and importance. Our first-principles calculations predicted three candidates for 2D-TIs, arsenene functionalized with F, OH and CH3 groups (AsX, X = F, OH and CH3), which preserved large bulk band gaps from 100 to 160 meV (up to 260 meV) derived from the spin-orbit coupling (SOC) within the px,y orbitals. This picture is similar to what was reported for an AsH monolayer with a band gap of 193 meV. Ab initio molecular dynamic (AIMD) simulations demonstrated the thermal stabilities of the AsX monolayers even at 500 K. The nontrivial topological phase was confirmed by the topological invariant Z2 and topological edge state. The topological electronic bandgap of the AsF monolayer can be effectively modulated by biaxial tensile strain and vertical external electric field. In addition, pronounced light absorption in the near-infrared and visible range of the solar spectrum was expected for the AsX (X = H, F) monolayers from the adsorption peaks at 0.45-1.6 eV, which is attractive for light harvesting. The nontrivial quantum spin Hall (QSH) insulators AsX could be promising candidates for practical room-temperature applications in dissipationless transport devices and photovoltaics.The search for new two-dimensional topological insulators (2D-TIs) with large band gaps is of great interest and importance. Our first-principles calculations predicted three candidates for 2D-TIs, arsenene functionalized with F, OH and CH3 groups (AsX, X = F, OH and CH3), which preserved large bulk band gaps from 100 to 160 meV (up to 260 meV) derived from the spin-orbit coupling (SOC) within the px,y orbitals. This picture is similar to what was reported for an AsH monolayer with a band gap of 193 meV. Ab initio molecular dynamic (AIMD) simulations demonstrated the thermal stabilities of the AsX monolayers even at 500 K. The nontrivial topological phase was confirmed by the topological

  9. Charge carrier localization effects on the quantum efficiency and operating temperature range of InAsxP1-x/InP quantum well detectors

    NASA Astrophysics Data System (ADS)

    Vashisht, Geetanjali; Dixit, V. K.; Porwal, S.; Kumar, R.; Sharma, T. K.; Oak, S. M.

    2016-03-01

    The effect of charge carrier localization resulting in "S-shaped" temperature dependence of the photoluminescence peak energy of InAsxP1-x/InP quantum wells (QWs) is distinctly revealed by the temperature dependent surface photo voltage (SPV) and photoconductivity (PC) processes. It is observed that the escape efficiency of carriers from QWs depends on the localization energy, where the carriers are unable to contribute in SPV/PC signal below a critical temperature. Below the critical temperature, carriers are strongly trapped in the localized states and are therefore unable to escape from the QW. Further, the critical temperature increases with the magnitude of localization energy of carriers. Carrier localization thus plays a pivotal role in defining the operating temperature range of InAsxP1-x/InP QW detectors.

  10. [The skull of Combe Capelle].

    PubMed

    Hoffmann, Almut; Wegner, Dietrich

    2002-12-01

    Since the end of World War II two of the most important anthropological artefacts of the Museum für Vor- und Frühgeschichte in Berlin, the skulls and skeletons of Le Moustier and Combe Capelle, were believed to be missing or destroyed, respectively. The postcrania were severely damaged during a fire after the museum was bombed in February 1945, while the skulls were brought to the Soviet Union in 1945. In 1965, the skull of the Neanderthal man from Le Moustier and the chain of the grave of Combe Capelle were found amongst the art objects returned by the Soviet Union into the German Democratic Republic in 1958. However, the Combe Capelle skull was still missing. In the end of 2001 this skull could be found and identified in a store-house of the museum. Now, one the oldest known representatives of Homo sapiens sapiens is again available for scientific research and public exhibitions. PMID:12529957

  11. Monolithically integrated absolute frequency comb laser system

    DOEpatents

    Wanke, Michael C.

    2016-07-12

    Rather than down-convert optical frequencies, a QCL laser system directly generates a THz frequency comb in a compact monolithically integrated chip that can be locked to an absolute frequency without the need of a frequency-comb synthesizer. The monolithic, absolute frequency comb can provide a THz frequency reference and tool for high-resolution broad band spectroscopy.

  12. On Frequency Combs in Monolithic Resonators

    NASA Astrophysics Data System (ADS)

    Savchenkov, A. A.; Matsko, A. B.; Maleki, L.

    2016-06-01

    Optical frequency combs have become indispensable in astronomical measurements, biological fingerprinting, optical metrology, and radio frequency photonic signal generation. Recently demonstrated microring resonator-based Kerr frequency combs point the way towards chip scale optical frequency comb generator retaining major properties of the lab scale devices. This technique is promising for integrated miniature radiofrequency and microwave sources, atomic clocks, optical references and femtosecond pulse generators. Here we present Kerr frequency comb development in a historical perspective emphasizing its similarities and differences with other physical phenomena. We elucidate fundamental principles and describe practical implementations of Kerr comb oscillators, highlighting associated solved and unsolved problems.

  13. Correlation between structure and physical properties of chalcogenide glasses in the AsxSe1-x system

    NASA Astrophysics Data System (ADS)

    Yang, Guang; Bureau, Bruno; Rouxel, Tanguy; Gueguen, Yann; Gulbiten, Ozgur; Roiland, Claire; Soignard, Emmanuel; Yarger, Jeffery L.; Troles, Johann; Sangleboeuf, Jean-Christophe; Lucas, Pierre

    2010-11-01

    Physical properties of chalcogenide glasses in the AsxSe1-x system have been measured as a function of composition including the Young’s modulus E , shear modulus G , bulk modulus K , Poisson’s ratio ν , the density ρ , and the glass transition Tg . All these properties exhibit a relatively sharp extremum at the average coordination number ⟨r⟩=2.4 . The structural origin of this trend is investigated by Raman spectroscopy and nuclear magnetic resonance. It is shown that the reticulation of the glass structure increases continuously until x=0.4 following the “chain crossing model” and then undergoes a transition toward a lower dimension pyramidal network containing an increasing number of molecular inclusions at x>0.4 . Simple theoretical estimates of the network bonding energy confirm a mismatch between the values of mechanical properties measured experimentally and the values predicted from a continuously reticulated structure, therefore corroborating the formation of a lower dimension network at high As content. The evolution of a wide range of physical properties is consistent with this sharp structural transition and suggests that there is no intermediate phase in these glasses at room temperature.

  14. Red, Green, and Blue Astro-combs

    NASA Astrophysics Data System (ADS)

    Phillips, David; Glenday, Alex; Li, Chih-Hao; Korzennik, Sylvain; Noah Chang, Guoqing; Chen, Li-Jin; Benedick, Andrew; Kaertner, Franz; Sasselov, Dimitar; Szentgyorgyi, Andrew; Walsworth, Ronald

    2011-06-01

    Searches for extrasolar planets using the periodic Doppler shift of stellar lines are approaching Earth-like planet sensitivity. Astro-combs, a combination of an octave spanning femtosecond laser and a mode-filtering cavity provide a likely route to increased calibration precision and accuracy. We present results from three astro-combs operating in the red/near-IR, green and blue spectral ranges. Light from a 1-GHz, octave-spanning Ti:Sapphire laser is filtered by a Fabry-Perot Cavity (FPC) constructed from Doubly-Chirped Mirrors to produce a red astro-comb with 100 nm of optical bandwidth. This astro-comb has calibrated an astrophysical spectrograph at the 1 m/s level. In the blue astro-comb, Ti:Sapphire comb light, doubled in a BBO crystal is filtered to 50 GHz mode spacing with an FPC. The blue astro-comb has performed 50 cm/s calibrations. In the ``green'' astro-comb, light from the 1 GHz Ti:Sapphire comb laser is broadened in a photonic crystal fiber optimized to produce light in the green. This 1-GHz spaced green light is then filtered to roughly 40 GHz via an FPC with zero group delay dispersion mirrors, providing approximately 50 nm of astro-comb light centered near 550 nm.

  15. A Josephson radiation comb generator

    PubMed Central

    Solinas, P.; Gasparinetti, S.; Golubev, D.; Giazotto, F.

    2015-01-01

    We propose the implementation of a Josephson Radiation Comb Generator (JRCG) based on a dc superconducting quantum interference device (SQUID) driven by an external magnetic field. When the magnetic flux crosses a diffraction node of the critical current interference pattern, the superconducting phase undergoes a jump of π and a voltage pulse is generated at the extremes of the SQUID. Under periodic drive this allows one to generate a sequence of sharp, evenly spaced voltage pulses. In the frequency domain, this corresponds to a comb-like structure similar to the one exploited in optics and metrology. With this device it is possible to generate up to several hundreds of harmonics of the driving frequency. For example, a chain of 50 identical high-critical-temperature SQUIDs driven at 1 GHz can deliver up to a 0.5 nW at 200 GHz. The availability of a fully solid-state radiation comb generator such as the JRCG, easily integrable on chip, may pave the way to a number of technological applications, from metrology to sub-millimeter wave generation. PMID:26193628

  16. A Josephson radiation comb generator.

    PubMed

    Solinas, P; Gasparinetti, S; Golubev, D; Giazotto, F

    2015-01-01

    We propose the implementation of a Josephson Radiation Comb Generator (JRCG) based on a dc superconducting quantum interference device (SQUID) driven by an external magnetic field. When the magnetic flux crosses a diffraction node of the critical current interference pattern, the superconducting phase undergoes a jump of π and a voltage pulse is generated at the extremes of the SQUID. Under periodic drive this allows one to generate a sequence of sharp, evenly spaced voltage pulses. In the frequency domain, this corresponds to a comb-like structure similar to the one exploited in optics and metrology. With this device it is possible to generate up to several hundreds of harmonics of the driving frequency. For example, a chain of 50 identical high-critical-temperature SQUIDs driven at 1 GHz can deliver up to a 0.5 nW at 200 GHz. The availability of a fully solid-state radiation comb generator such as the JRCG, easily integrable on chip, may pave the way to a number of technological applications, from metrology to sub-millimeter wave generation. PMID:26193628

  17. On-chip dual-comb based on quantum cascade laser frequency combs

    SciTech Connect

    Villares, G. Wolf, J.; Kazakov, D.; Süess, M. J.; Beck, M.; Faist, J.; Hugi, A.

    2015-12-21

    Dual-comb spectroscopy is emerging as an appealing application of mid-infrared frequency combs for high-resolution molecular spectroscopy, as it leverages on the unique coherence properties of frequency combs. Here, we present an on-chip dual-comb source based on mid-infrared quantum cascade laser frequency combs. Control of the combs repetition and offset frequencies is obtained by integrating micro-heaters next to each laser. We show that a full control of the dual-comb system is possible, by measuring a multi-heterodyne beating corresponding to an optical bandwidth of 32 cm{sup −1} centered at 1330 cm{sup −1} (7.52 μm), demonstrating that this device represents a critical step towards compact dual-comb systems.

  18. Ultrafast electrooptic dual-comb interferometry.

    PubMed

    Durán, Vicente; Tainta, Santiago; Torres-Company, Victor

    2015-11-16

    Dual-comb interferometry is a particularly compelling technique that relies on the phase coherence of two laser frequency combs for measuring broadband complex spectra. This method is rapidly advancing the field of optical spectroscopy and empowering new applications, from nonlinear microscopy to laser ranging. Up to now, most dual-comb interferometers were based on modelocked lasers, whose repetition rates have restricted the measurement speed to ~kHz. Here we demonstrate a dual-comb interferometer that is based on electrooptic frequency combs and measures consecutive complex spectra at an ultra-high refresh rate of 25 MHz. These results pave the way for novel scientific and metrology applications of frequency comb generators beyond the realm of molecular spectroscopy, where the measurement of ultrabroadband waveforms is of paramount relevance. PMID:26698533

  19. Efficient optical frequency-comb generator

    NASA Astrophysics Data System (ADS)

    Bell, A. S.; McFarlane, G. M.; Riis, E.; Ferguson, A. I.

    1995-06-01

    We have demonstrated a method that efficiently transfers the power from a single-frequency laser into a wideband frequency comb. The comb was produced by a 2.7-GHz electro-optic modulator in a resonant optical cavity. A coupled cavity technique was used to transfer 8.5% of the laser power into a comb with a span of 400 modes, or more than 1 THz.

  20. Scaling of Yb-Fiber Frequency Combs

    NASA Astrophysics Data System (ADS)

    Ruehl, Axel; Marcinkevicius, Andrius; Fermann, Martin E.; Hartl, Ingmar

    2010-06-01

    Immediately after their introduction in 1999, femtosecond laser frequency combs revolutionized the field of precision optical frequency metrology and are key elements in many experiments. Frequency combs based on femtosecond Er-fiber lasers based were demonstrated in 2005, allowing additionally rugged, compact set-ups and reliable unattended long-term operation. The introduction of Yb-fiber technology led to an dramatic improvement in fiber-comb performance in various aspects. Low-noise Yb-fiber femtosecond oscillators enabled a reduction of relative comb tooth linewidth to the sub-Hz level as well as scaling of the fundamental comb spacings up to 1 GHz. This is beneficial for any frequency-domain comb application due to the higher power per comb-mode. Many spectroscopic applications require, however, frequency combs way beyond the wavelength range accessible with broad band laser materials, so nonlinear conversion and hence higher peak intensity is required. We demonstrated power scaling of Yb-fiber frequency combs up to 80 W average power in a strictly linear chirped-pulse amplification schemes compatible with low-noise phase control. These high-power Yb-fiber-frequency combs facilitated not only the extension to the mid-IR spectral region. When coupled to a passive enhancement cavity, the average power can be further scaled to the kW-level opening new capabilities for XUV frequency combs via high-harmonic generation. All these advances of fiber-based frequency combs will trigger many novel applications both in fundamental and applied sciences. Schibli et al., Nature Photonics 2 355 (2008). Hartl et al., MF9 in Advanced Solid-State Photonics. 2009, Optical Society of America. Ruehl et al., AWC7 in Advanced Solid-State Photonics. 2010, Optical Society of America. Adler et al., Optics Letters 34 1330 (2009). Yost et al., Nature Physics 5 815 (2009).

  1. Calculation of tunable type-II band alignments in InAsxSbyP1-x-y/InAs heterojunctions

    NASA Astrophysics Data System (ADS)

    Shim, Kyurhee

    2016-01-01

    The energy band gaps of the alloy InAsxSbyP1-x-y are calculated using the correlated function expansion (CFE) technique over the entire composition space x and y, for which the CFE band gap composition contour for the mid-infrared (MIR) spectral region of 2 (0.62)-5 µm (0.25 eV) is presented. The composition dependence of the valence-band maximum (VBM) is obtained using the universal tight binding (UTB) method, and the corresponding conduction-band minimum (CBM) can be computed from the difference between the band gap and the VBM. By organizing the relative positions of the VBM and CBM between the quaternary alloy InAsSbP and the binary compound InAs, the band alignments and band types of InAsSbP/InAs heterojunctions (HJs) along the lattice-matching conditions x and y [i.e., y = 0.311(1 - x)] are determined. It is found that the VBMs of the alloy InAsxSbyP1-x-y are located within the band gap of InAs, whereas the CBMs of the alloy lie outside the band gap of InAs over the entire composition range. This implies that the InAsxSbyP1-x-y/InAs HJs exhibit composition-tunable, type-II (staggered) band alignments. In addition, the conduction-band offset (CBO) and valence-band offset (VBO) of InAsSbP/InAs HJs both present the upward bowing trend, with the CBO curves appearing sharp and the VBO curves appearing smooth.

  2. Normal-dispersion microresonator Kerr frequency combs

    NASA Astrophysics Data System (ADS)

    Xue, Xiaoxiao; Qi, Minghao; Weiner, Andrew M.

    2016-06-01

    Optical microresonator-based Kerr frequency comb generation has developed into a hot research area in the past decade. Microresonator combs are promising for portable applications due to their potential for chip-level integration and low power consumption. According to the group velocity dispersion of the microresonator employed, research in this field may be classified into two categories: the anomalous dispersion regime and the normal dispersion regime. In this paper, we discuss the physics of Kerr comb generation in the normal dispersion regime and review recent experimental advances. The potential advantages and future directions of normal dispersion combs are also discussed.

  3. Bichromatically pumped microresonator frequency combs

    NASA Astrophysics Data System (ADS)

    Hansson, T.; Wabnitz, S.

    2014-07-01

    A study is made of the nonlinear dynamics of bichromatically pumped microresonator Kerr frequency combs described by a driven and damped nonlinear Schrödinger equation, with an additional degree of freedom in the form of the modulation frequency. A truncated four-wave model is derived for the pump modes and the dominant sideband pair, which is found to be able to describe much of the essential dynamical behavior of the full equation. The stability of stationary states within the four-wave model is investigated, and numerical simulations are made to demonstrate that a large range of solutions, including cavity solitons, are possible beyond previously considered low-intensity patterns.

  4. Arthur Wright Combs: A Humanistic Pioneer

    ERIC Educational Resources Information Center

    Magnuson, Sandy

    2012-01-01

    Arthur Wright Combs (1912-1999) championed humanistic counseling and education. He proposed a theory that incorporated humanistic values and cognitive factors. This article features a review of his contributions, an overview of his theory, a synthesis of stories about Combs that were acquired during research interviews, and my commentary on his…

  5. Light beam frequency comb generator

    DOEpatents

    Priatko, Gordon J.; Kaskey, Jeffrey A.

    1992-01-01

    A light beam frequency comb generator uses an acousto-optic modulator to generate a plurality of light beams with frequencies which are uniformly separated and possess common noise and drift characteristics. A well collimated monochromatic input light beam is passed through this modulator to produce a set of both frequency shifted and unshifted optical beams. An optical system directs one or more frequency shifted beams along a path which is parallel to the path of the input light beam such that the frequency shifted beams are made incident on the modulator proximate to but separated from the point of incidence of the input light beam. After the beam is thus returned to and passed through the modulator repeatedly, a plurality of mutually parallel beams are generated which are frequency-shifted different numbers of times and possess common noise and drift characteristics.

  6. Light beam frequency comb generator

    DOEpatents

    Priatko, G.J.; Kaskey, J.A.

    1992-11-24

    A light beam frequency comb generator uses an acousto-optic modulator to generate a plurality of light beams with frequencies which are uniformly separated and possess common noise and drift characteristics. A well collimated monochromatic input light beam is passed through this modulator to produce a set of both frequency shifted and unshifted optical beams. An optical system directs one or more frequency shifted beams along a path which is parallel to the path of the input light beam such that the frequency shifted beams are made incident on the modulator proximate to but separated from the point of incidence of the input light beam. After the beam is thus returned to and passed through the modulator repeatedly, a plurality of mutually parallel beams are generated which are frequency-shifted different numbers of times and possess common noise and drift characteristics. 2 figs.

  7. Ultrabroadband coherent supercontinuum frequency comb

    SciTech Connect

    Ruehl, Axel; McKay, Hugh; Thomas, Brian; Dong, Liang; Fermann, Martin E.; Hartl, Ingmar; Martin, Michael J.; Cossel, Kevin C.; Chen Lisheng; Benko, Craig; Ye Jun; Dudley, John M.

    2011-07-15

    We present detailed studies of the coherence properties of an ultrabroadband supercontinuum, enabled by a comprehensive approach involving continuous-wave laser sources to independently probe both the amplitude and phase noise quadratures across the entire spectrum. The continuum coherently spans more than 1.5 octaves, supporting Hz-level comparison of ultrastable lasers at 698 nm and 1.54 {mu}m. We present a complete numerical simulation of the accumulated comb coherence in the limit of many pulses, in contrast to the single-pulse level, with systematic experimental verification. The experiment and numerical simulations reveal the presence of quantum-seeded broadband amplitude noise without phase coherence degradation, including the discovery of a dependence of the supercontinuum coherence on the fiber fractional Raman gain.

  8. Comb-Net: a high-density WDM network with centralized wavelength combs

    NASA Astrophysics Data System (ADS)

    Gerla, Mario; Chiaretti, Guido; Rotolo, Salvatore

    1993-11-01

    In this paper, we propose Comb-Net, a tree PON architecture in which several laser combs at the root of the tree supply wavelengths to all stations in the PON. Namely, each station receives several wavelengths from comb laser sources located at the root of the PON, via a Comb Distribution network. It then selects (by fixed or tunable filters) some predefined or agreed upon wavelengths, and uses these as sources; i.e., it modulates them (in amplitude or phase) using an external modulator. The modulated wavelengths are then transmitted on the Multiaccess Communications network, which is separate from the Comb Distribution network. The novelty of Comb-Net is to replace the individual (fixed or tunable) lasers at the station with a set of centralized comb generators. The advantages are better stability control, lower noise and potentially lower cost since each station does not require a dedicated source. In the paper, we describe an example of Comb-Net architecture in which the Multiaccess Data network is based on a physical tree topology and on two separate virtual topologies embedded within the physical topology using WDM: a single hop topology used for circuit switched connections; and a multihop topology used for packet switched traffic. We illustrate the Comb-Net architecture with a simple case study.

  9. Tracking Comb Filter Suppresses Welder Harmonics

    NASA Technical Reports Server (NTRS)

    Delcher, Ray C.

    1992-01-01

    Tracking comb filter includes charge-coupled-device delay line and phase-locked loop. Filter removes harmonics of frequency of repetition of welding-current pulses from acoustic-emission signal. Spurious signals reduced almost to fundamental limit.

  10. Frequency Comb Generation in Superconducting Resonators

    NASA Astrophysics Data System (ADS)

    Pappas, David; Erickson, Robert; Vissers, Michael; Ku, Hsiang-Sheng

    2015-03-01

    We have generated frequency combs spanning 0.5 to 20 GHz in superconducting λ = 2 resonators at T =3 K. Thin films of niobium-titanium nitride enabled this development due to their low loss, high nonlinearity, low frequency dispersion, and high critical temperature. The combs nucleate as sidebands around multiples of the pump frequency. Selection rules for the allowed frequency emission are calculated using perturbation theory, and the measured spectrum is shown to agree with the theory. Sideband spacing is measured to be accurate to 1 part in 108 The sidebands coalesce into a continuous comb structure observed to cover at least several frequency octaves. Generation of combs in this frequency range allows for unprecedented analysis of this non-linear phenomena in the time domain. We acknowledge DARPA and the NIST Quantum Information program.

  11. Frequency comb transferred by surface plasmon resonance.

    PubMed

    Geng, Xiao Tao; Chun, Byung Jae; Seo, Ji Hoon; Seo, Kwanyong; Yoon, Hana; Kim, Dong-Eon; Kim, Young-Jin; Kim, Seungchul

    2016-01-01

    Frequency combs, millions of narrow-linewidth optical modes referenced to an atomic clock, have shown remarkable potential in time/frequency metrology, atomic/molecular spectroscopy and precision LIDARs. Applications have extended to coherent nonlinear Raman spectroscopy of molecules and quantum metrology for entangled atomic qubits. Frequency combs will create novel possibilities in nano-photonics and plasmonics; however, its interrelation with surface plasmons is unexplored despite the important role that plasmonics plays in nonlinear spectroscopy and quantum optics through the manipulation of light on a subwavelength scale. Here, we demonstrate that a frequency comb can be transformed to a plasmonic comb in plasmonic nanostructures and reverted to the original frequency comb without noticeable degradation of <6.51 × 10(-19) in absolute position, 2.92 × 10(-19) in stability and 1 Hz in linewidth. The results indicate that the superior performance of a well-defined frequency comb can be applied to nanoplasmonic spectroscopy, quantum metrology and subwavelength photonic circuits. PMID:26898307

  12. Frequency comb transferred by surface plasmon resonance

    NASA Astrophysics Data System (ADS)

    Geng, Xiao Tao; Chun, Byung Jae; Seo, Ji Hoon; Seo, Kwanyong; Yoon, Hana; Kim, Dong-Eon; Kim, Young-Jin; Kim, Seungchul

    2016-02-01

    Frequency combs, millions of narrow-linewidth optical modes referenced to an atomic clock, have shown remarkable potential in time/frequency metrology, atomic/molecular spectroscopy and precision LIDARs. Applications have extended to coherent nonlinear Raman spectroscopy of molecules and quantum metrology for entangled atomic qubits. Frequency combs will create novel possibilities in nano-photonics and plasmonics; however, its interrelation with surface plasmons is unexplored despite the important role that plasmonics plays in nonlinear spectroscopy and quantum optics through the manipulation of light on a subwavelength scale. Here, we demonstrate that a frequency comb can be transformed to a plasmonic comb in plasmonic nanostructures and reverted to the original frequency comb without noticeable degradation of <6.51 × 10-19 in absolute position, 2.92 × 10-19 in stability and 1 Hz in linewidth. The results indicate that the superior performance of a well-defined frequency comb can be applied to nanoplasmonic spectroscopy, quantum metrology and subwavelength photonic circuits.

  13. Frequency comb transferred by surface plasmon resonance

    PubMed Central

    Geng, Xiao Tao; Chun, Byung Jae; Seo, Ji Hoon; Seo, Kwanyong; Yoon, Hana; Kim, Dong-Eon; Kim, Young-Jin; Kim, Seungchul

    2016-01-01

    Frequency combs, millions of narrow-linewidth optical modes referenced to an atomic clock, have shown remarkable potential in time/frequency metrology, atomic/molecular spectroscopy and precision LIDARs. Applications have extended to coherent nonlinear Raman spectroscopy of molecules and quantum metrology for entangled atomic qubits. Frequency combs will create novel possibilities in nano-photonics and plasmonics; however, its interrelation with surface plasmons is unexplored despite the important role that plasmonics plays in nonlinear spectroscopy and quantum optics through the manipulation of light on a subwavelength scale. Here, we demonstrate that a frequency comb can be transformed to a plasmonic comb in plasmonic nanostructures and reverted to the original frequency comb without noticeable degradation of <6.51 × 10−19 in absolute position, 2.92 × 10−19 in stability and 1 Hz in linewidth. The results indicate that the superior performance of a well-defined frequency comb can be applied to nanoplasmonic spectroscopy, quantum metrology and subwavelength photonic circuits. PMID:26898307

  14. Frequency Comb Velocity Modulation Spectroscopy

    NASA Astrophysics Data System (ADS)

    Cossel, Kevin C.; Sinclair, Laura C.; Coffey, Tyler; Cornell, Eric; Ye, Jun

    2011-06-01

    We have developed a novel technique for rapid ion-sensitive spectroscopy over a broad spectral bandwidth by combining the high sensitivity of velocity modulation spectroscopy (VMS) with the parallel nature and high frequency accuracy of cavity-enhanced direct frequency comb spectroscopy. Prior to this research, no techniques have been capable of high sensitivity velocity modulation spectroscopy on every parallel detection channel over such a broad spectral range. We have demonstrated the power of this technique by measuring the A^2Π_u - X^2Σ_g^+ (4,2) band of N_2^+ at 830 nm with an absorption sensitivity of 1×10-6 for each of 1500 simultaneous measurement channels spanning 150 Cm-1. A densely sampled spectrum consisting of interleaved measurements to achieve 75 MHz spacing is acquired in under an hour. This technique is ideally suited for high resolution survey spectroscopy of molecular ions with applications including chemical physics, astrochemistry, and precision measurement. Currently, this system is being used to map the electronic transitions of HfF^+ for the JILA electron electric dipole moment (eEDM) experiment. The JILA eEDM experiment uses trapped molecular ions to significantly increase the coherence time of the measurement in addition to utilizing the strong electric field enhancement available from molecules. Previous theoretical work has shown that the metastable ^3Δ_1 state in HfF^+ and ThF^+ provides high sensitivity to the eEDM and good cancellation of systematic effects; however, the electronic level structure of these species have not previously been measured, and the theoretical uncertainties are hundreds to thousands of wavenumbers. This necessitates broad-bandwidth, high-resolution survey spectroscopy provided by frequency comb VMS in the 700-900 nm spectral window. F. Adler, M. J. Thorpe, K. C. Cossel, and J. Ye. Annu. Rev. Anal. Chem. 3, 175-205 (2010) A. E. Leanhardt, et. al. arXiv:1008.2997v2 E. Meyer, J. L. Bohn, and M. P. Deskevich

  15. Phase steps and resonator detuning measurements in microresonator frequency combs.

    PubMed

    Del'Haye, Pascal; Coillet, Aurélien; Loh, William; Beha, Katja; Papp, Scott B; Diddams, Scott A

    2015-01-01

    Experiments and theoretical modelling yielded significant progress toward understanding of Kerr-effect induced optical frequency comb generation in microresonators. However, the simultaneous Kerr-mediated interaction of hundreds or thousands of optical comb frequencies with the same number of resonator modes leads to complicated nonlinear dynamics that are far from fully understood. An important prerequisite for modelling the comb formation process is the knowledge of phase and amplitude of the comb modes as well as the detuning from their respective microresonator modes. Here, we present comprehensive measurements that fully characterize optical microcomb states. We introduce a way of measuring resonator dispersion and detuning of comb modes in a hot resonator while generating an optical frequency comb. The presented phase measurements show unpredicted comb states with discrete π and π/2 steps in the comb phases that are not observed in conventional optical frequency combs. PMID:25565467

  16. George Combe and common sense.

    PubMed

    Dyde, Sean

    2015-06-01

    This article examines the history of two fields of enquiry in late eighteenth- and early nineteenth-century Scotland: the rise and fall of the common sense school of philosophy and phrenology as presented in the works of George Combe. Although many previous historians have construed these histories as separate, indeed sometimes incommensurate, I propose that their paths were intertwined to a greater extent than has previously been given credit. The philosophy of common sense was a response to problems raised by Enlightenment thinkers, particularly David Hume, and spurred a theory of the mind and its mode of study. In order to succeed, or even to be considered a rival of these established understandings, phrenologists adapted their arguments for the sake of engaging in philosophical dispute. I argue that this debate contributed to the relative success of these groups: phrenology as a well-known historical subject, common sense now largely forgotten. Moreover, this history seeks to question the place of phrenology within the sciences of mind in nineteenth-century Britain. PMID:25921681

  17. Laboratory duplication of comb layering in the Rhum pluton. [igneous rocks with comb layered texture

    NASA Technical Reports Server (NTRS)

    Donaldson, C. H.

    1977-01-01

    A description is provided of the texture of harrisite comb layers, taking into account the results of crystallization experiments at controlled cooling rates, which have reproduced the textural change from 'cumulate' to comb-layered harrisite. Melted samples of harrisite were used in the dynamic crystallization experiments considered. The differentiation of a cooling rate run with respect to olivine grain size and shape is shown and three possible origins of hopper olivine in differentiated crystallization runs are considered. It is found that olivine nucleation occurred throughout cooling, except for the incubation period during early cooling. The elongate combed olivines in harrisite apparently grew as the magma locally supercooled to at least 30 C. It is suggested that the branching crystals in most comb layers, including comb-layered harrisite, probably grew along thermal gradients.

  18. Optical Frequency Comb Generation based on Erbium Fiber Lasers

    NASA Astrophysics Data System (ADS)

    Droste, Stefan; Ycas, Gabriel; Washburn, Brian R.; Coddington, Ian; Newbury, Nathan R.

    2016-06-01

    Optical frequency combs have revolutionized optical frequency metrology and are being actively investigated in a number of applications outside of pure optical frequency metrology. For reasons of cost, robustness, performance, and flexibility, the erbium fiber laser frequency comb has emerged as the most commonly used frequency comb system and many different designs of erbium fiber frequency combs have been demonstrated. We review the different approaches taken in the design of erbium fiber frequency combs, including the major building blocks of the underlying mode-locked laser, amplifier, supercontinuum generation and actuators for stabilization of the frequency comb.

  19. Low noise electro-optic comb generation by fully stabilizing to a mode-locked fiber comb.

    PubMed

    Kuse, Naoya; Schibli, Thomas R; Fermann, Martin E

    2016-07-25

    A fully stabilized EO comb is demonstrated by phase locking the two degrees of freedom of an EO comb to a low noise mode-locked fiber comb. Division/magnification of residual phase noise of locked beats is observed by measuring an out-of-loop beat. By phase locking the 200 th harmonics of the EO comb and a driving cw frequency to a fiber comb, a record low phase noise EO comb across +/- 200 harmonics (from 1544.8 nm to 1577.3 nm) is demonstrated. PMID:27464140

  20. Ultrasonic comb transducer for smart materials

    NASA Astrophysics Data System (ADS)

    Rose, J. L.

    1998-04-01

    Installation of a small multi-element comb type ultrasonic transducer is proposed as a component of a smart structure. It can be used in either an active or passive mode in carrying out ultrasonic bulk or guided wave nondestructive evaluation. Theoretical methods are developed and experimental results are presented for guided wave generation and mode control with this very efficient and versatile novel comb type ultrasonic transducer. Excitation and probe design is crucial in mode selection. The comb transducer generates waves that are influenced by such parameters as number of elements, spacing between elements, dimension, pulsing sequence, and pressure distribution. The excited elastic field depends on the excitation frequency, plate thickness, and elastic properties. Techniques are studied to optimize the applied loading and the comb transducer design parameters so that only modes that are most sensitive to particular material characteristics can be generated. Complete understanding of the comb transducer parameters and their impact on the elastic field allows us to efficiently generate higher order modes as well as low phase velocity modes which are valuable in composite material characterization. Sample experiments are presented for various plate and tube like structures.

  1. Electrostatic comb drive for vertical actuation

    SciTech Connect

    Lee, A. P., LLNL

    1997-07-10

    The electrostatic comb finger drive has become an integral design for microsensor and microactuator applications. This paper reports on utilizing the levitation effect of comb fingers to design vertical-to-the-substrate actuation for interferometric applications. For typical polysilicon comb drives with 2 {micro}m gaps between the stationary and moving fingers, as well as between the microstructures and the substrate, the equilibrium position is nominally 1-2 {micro}m above the stationary comb fingers. This distance is ideal for many phase shifting interferometric applications. Theoretical calculations of the vertical actuation characteristics are compared with the experimental results, and a general design guideline is derived from these results. The suspension flexure stiffnesses, gravity forces, squeeze film damping, and comb finger thicknesses are parameters investigated which affect the displacement curve of the vertical microactuator. By designing a parallel plate capacitor between the suspended mass and the substrate, in situ position sensing can be used to control the vertical movement, providing a total feedback-controlled system. Fundamentals of various capacitive position sensing techniques are discussed. Experimental verification is carried out by a Zygo distance measurement interferometer.

  2. Nonlinear transmission spectroscopy with dual frequency combs

    NASA Astrophysics Data System (ADS)

    Glenn, Rachel; Mukamel, Shaul

    2014-08-01

    We show how two frequency combs E1, E2 can be used to measure single-photon, two-photon absorption (TPA), and Raman resonances in a molecule with three electronic bands, by detecting the radio frequency modulation of the nonlinear transmission signal. Some peaks are independent of the carrier frequency of the comb and others shift with that frequency and have a width close to the comb width. TPA and Raman resonances independent of the carrier frequency are selected by measuring the transmission signal ˜E12E22 and the single-photon resonances are selected by measuring the transmission signal ˜E13E2. Sinusoidal spectral phase shaping strongly affects the TPA, but not the Raman resonances.

  3. Generation of ultra-low-noise optical parametric combs

    NASA Astrophysics Data System (ADS)

    Kuo, Ping P.; Radic, Stojan

    2016-03-01

    Generation of wideband optical frequency combs requires precise balance between nonlinear photon interaction and parasitic effects. While near-octave combs can be generated in both silica and silicon waveguides, it is not always possible to suppress the noise across the operational bandwidth. Principles and challenges of noiseinhibited, tunable frequency comb generation in cavity-free parametric mixers are described and discussed.

  4. High-Temperature Thermoelectric Properties of the Solid–Solution Zintl Phase Eu11Cd6Sb12–xAsx (x < 3)

    SciTech Connect

    Kazem, Nasrin; Xie, Weiwei; Ohno, Saneyuki; Zevalkink, Alexandra; Miller, Gordon J; Snyder, G Jeffrey; Kauzlarich, Susan M

    2014-02-11

    Zintl phases are compounds that have shown promise for thermoelectric applications. The title solid–solution Zintl compounds were prepared from the elements as single crystals using a tin flux for compositions x = 0, 1, 2, and 3. Eu11Cd6Sb12–xAsx (x < 3) crystallize isostructurally in the centrosymmetric monoclinic space group C2/m (no. 12, Z = 2) as the Sr11Cd6Sb12 structure type (Pearson symbol mC58). Efforts to make the As compositions for x exceeding ~3 resulted in structures other than the Sr11Cd6Sb12 structure type. Single-crystal X-ray diffraction indicates that As does not randomly substitute for Sb in the structure but is site specific for each composition. The amount of As determined by structural refinement was verified by electron microprobe analysis. Electronic structures and energies calculated for various model structures of Eu11Cd6Sb10As2 (x = 2) indicated that the preferred As substitution pattern involves a mixture of three of the six pnicogen sites in the asymmetric unit. In addition, As substitution at the Pn4 site opens an energy gap at the Fermi level, whereas substitution at the other five pnicogen sites remains semimetallic with a pseudo gap. Thermoelectric properties of these compounds were measured on hot-pressed, fully densified pellets. Samples show exceptionally low lattice thermal conductivities from room temperature to 775 K: 0.78–0.49 W/mK for x = 0; 0.72–0.53 W/mK for x = 1; and 0.70–0.56 W/mK for x = 2. Eu11Cd6Sb12 shows a high p-type Seebeck coefficient (from +118 to 153 μ V/K) but also high electrical resistivity (6.8 to 12.8 mΩ·cm). The value of zT reaches 0.23 at 774 K. The properties of Eu11Cd6Sb12–xAsx are interpreted in discussion with the As site substitution.

  5. Dual-comb spectroscopy based on quantum-cascade-laser frequency combs.

    PubMed

    Villares, Gustavo; Hugi, Andreas; Blaser, Stéphane; Faist, Jérôme

    2014-01-01

    Dual-comb spectroscopy performed in the mid-infrared-where molecules have their strongest rotovibrational absorption lines-offers the promise of high spectral resolution broadband spectroscopy with very short acquisition times (μs) and no moving parts. Recently, we demonstrated frequency comb operation of a quantum-cascade-laser. We now use that device in a compact, dual-comb spectrometer. The noise properties of the heterodyne beat are close to the shot noise limit. Broadband (15 cm(-1)) high-resolution (80 MHz) absorption spectroscopy of both a GaAs etalon and water vapour is demonstrated, showing the potential of quantum-cascade-laser frequency combs as the basis for a compact, all solid-state, broadband chemical sensor. PMID:25307936

  6. Direct-comb molecular spectroscopy with accurate, resolved comb teeth over 43 THz.

    PubMed

    Zolot, A M; Giorgetta, F R; Baumann, E; Nicholson, J W; Swann, W C; Coddington, I; Newbury, N R

    2012-02-15

    We demonstrate a dual-comb spectrometer using stabilized frequency combs spanning 177 to 220 THz (1360 to 1690 nm) in the near infrared. Comb-tooth-resolved measurements of amplitude and phase generate over 4×10(5) individually resolved spectral elements at 100 MHz point spacing and kilohertz-level resolution and accuracy. The signal-to-noise ratio is 100 to 3000 per comb tooth. Doppler-broadened phase and amplitude spectra of CO(2), CH(4), C(2)H(2), and H(2)O in a 30 m multipass cell agree with established spectral parameters, achieving high-resolution measurements with optical bandwidth generally associated with blackbody sources. PMID:22344132

  7. Inter-comb synchronization by mode-to-mode locking

    NASA Astrophysics Data System (ADS)

    Chun, Byung Jae; Kim, Young-Jin; Kim, Seung-Woo

    2016-08-01

    Two combs of fiber femtosecond lasers are synchronized through the optical frequency reference created by injection-locking of a diode laser to a single comb mode. Maintaining a mHz-level narrow linewidth, the optical frequency reference permits two combs to be stabilized by mode-to-mode locking with a relative stability of 1.52  ×  10‑16 at 10 s with a frequency slip of 2.46 mHz. This inter-comb synchronization can be utilized for applications such as dual-comb spectroscopy or ultra-short pulse synthesis without extra narrow-linewidth lasers.

  8. Spectroscopy with Comb-Referenced Diode Lasers

    NASA Astrophysics Data System (ADS)

    Cich, Matthew; Lopez, Gary V.; Johnson, Philip M.; Sears, Trevor J.; McRaven, Christopher P.

    2010-06-01

    Extended cavity diode lasers have been stabilized by locking to components of an erbium-doped fiber laser-based frequency comb with a 250 MHz comb spacing centered at 1.5μ m. We find the Allan variance of the diode laser frequency relative to the single comb component to which it is locked is of the order of a few Hz. For the system as a whole, the absolute frequency accuracy is approximately 1.5 parts in 1012. In order to characterize the system more completely, we have recorded saturation dip absorption spectra of several transitions in the ν_1 + ν_3 combination band of acetylene near 6530 cm-1. We find good agreement with published absolute frequency measurements for these transitions, which have been used as secondary frequency standards in the past. Aside from extremely precise saturation dip measurements such as these, comb-stabilized lasers should permit excellent measurements of Doppler-broadened lineshapes, both to compare with theory and for analytical applications. Progress along these lines will be reported at the meeting. Acknowledgments: T. J. Sears gratefully acknowledges support from a Brookhaven National Laboratory program development grant that enabled this work and also support for research at Brookhaven National Laboratory which was carried out under Contract No. DE-AC02-98CH10886 with the U.S. Department of Energy and supported by its Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences and Biosciences.

  9. Time sequence photography of Roosters Comb

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The importance of understanding natural landscape changes is key in properly determining rangeland ecology. Time sequence photography allows a landscape snapshot to be documented and enables the ability to compare natural changes overtime. Photographs of Roosters Comb were taken from the same vantag...

  10. Phase separation of comb polymer nanocomposite melts.

    PubMed

    Xu, Qinzhi; Feng, Yancong; Chen, Lan

    2016-02-01

    In this work, the spinodal phase demixing of branched comb polymer nanocomposite (PNC) melts is systematically investigated using the polymer reference interaction site model (PRISM) theory. To verify the reliability of the present method in characterizing the phase behavior of comb PNCs, the intermolecular correlation functions of the system for nonzero particle volume fractions are compared with our molecular dynamics simulation data. After verifying the model and discussing the structure of the comb PNCs in the dilute nanoparticle limit, the interference among the side chain number, side chain length, nanoparticle-monomer size ratio and attractive interactions between the comb polymer and nanoparticles in spinodal demixing curves is analyzed and discussed in detail. The results predict two kinds of distinct phase separation behaviors. One is called classic fluid phase boundary, which is mediated by the entropic depletion attraction and contact aggregation of nanoparticles at relatively low nanoparticle-monomer attraction strength. The second demixing transition occurs at relatively high attraction strength and involves the formation of an equilibrium physical network phase with local bridging of nanoparticles. The phase boundaries are found to be sensitive to the side chain number, side chain length, nanoparticle-monomer size ratio and attractive interactions. As the side chain length is fixed, the side chain number has a large effect on the phase behavior of comb PNCs; with increasing side chain number, the miscibility window first widens and then shrinks. When the side chain number is lower than a threshold value, the phase boundaries undergo a process from enlarging the miscibility window to narrowing as side chain length increases. Once the side chain number overtakes this threshold value, the phase boundary shifts towards less miscibility. With increasing nanoparticle-monomer size ratio, a crossover of particle size occurs, above which the phase separation

  11. Broadband high-resolution X-ray frequency combs

    NASA Astrophysics Data System (ADS)

    Cavaletto, Stefano M.; Harman, Zoltán; Ott, Christian; Buth, Christian; Pfeifer, Thomas; Keitel, Christoph H.

    2014-07-01

    Optical frequency combs have had a remarkable impact on precision spectroscopy. Enabling this technology in the X-ray domain is expected to result in wide-ranging applications, such as stringent tests of astrophysical models and quantum electrodynamics, a more sensitive search for the variability of fundamental constants, and precision studies of nuclear structure. Ultraprecise X-ray atomic clocks may also be envisaged. In this work, an X-ray pulse-shaping method is proposed to generate a comb in the absorption spectrum of an ultrashort high-frequency pulse. The method employs an optical-frequency-comb laser, manipulating the system's dipole response to imprint a comb on an excited transition with a high photon energy. The described scheme provides higher comb frequencies and requires lower optical-comb peak intensities than currently explored methods, preserves the overall width of the optical comb, and may be implemented using currently available X-ray technology.

  12. The Rose-comb Mutation in Chickens Constitutes a Structural Rearrangement Causing Both Altered Comb Morphology and Defective Sperm Motility

    PubMed Central

    Boije, Henrik; Bed'hom, Bertrand; Fillon, Valérie; Dorshorst, Ben; Rubin, Carl-Johan; Liu, Ranran; Gao, Yu; Gu, Xiaorong; Wang, Yanqiang; Gourichon, David; Zody, Michael C.; Zecchin, William; Vieaud, Agathe; Tixier-Boichard, Michèle; Hu, Xiaoxiang; Hallböök, Finn; Li, Ning; Andersson, Leif

    2012-01-01

    Rose-comb, a classical monogenic trait of chickens, is characterized by a drastically altered comb morphology compared to the single-combed wild-type. Here we show that Rose-comb is caused by a 7.4 Mb inversion on chromosome 7 and that a second Rose-comb allele arose by unequal crossing over between a Rose-comb and wild-type chromosome. The comb phenotype is caused by the relocalization of the MNR2 homeodomain protein gene leading to transient ectopic expression of MNR2 during comb development. We also provide a molecular explanation for the first example of epistatic interaction reported by Bateson and Punnett 104 years ago, namely that walnut-comb is caused by the combined effects of the Rose-comb and Pea-comb alleles. Transient ectopic expression of MNR2 and SOX5 (causing the Pea-comb phenotype) occurs in the same population of mesenchymal cells and with at least partially overlapping expression in individual cells in the comb primordium. Rose-comb has pleiotropic effects, as homozygosity in males has been associated with poor sperm motility. We postulate that this is caused by the disruption of the CCDC108 gene located at one of the inversion breakpoints. CCDC108 is a poorly characterized protein, but it contains a MSP (major sperm protein) domain and is expressed in testis. The study illustrates several characteristic features of the genetic diversity present in domestic animals, including the evolution of alleles by two or more consecutive mutations and the fact that structural changes have contributed to fast phenotypic evolution. PMID:22761584

  13. Genome-Wide Association Studies for Comb Traits in Chickens

    PubMed Central

    Ma, Meng; Dou, Taocun; Lu, Jian; Guo, Jun; Hu, Yuping; Yi, Guoqiang; Yuan, Jingwei; Sun, Congjiao; Wang, Kehua; Yang, Ning

    2016-01-01

    The comb, as a secondary sexual character, is an important trait in chicken. Indicators of comb length (CL), comb height (CH), and comb weight (CW) are often selected in production. DNA-based marker-assisted selection could help chicken breeders to accelerate genetic improvement for comb or related economic characters by early selection. Although a number of quantitative trait loci (QTL) and candidate genes have been identified with advances in molecular genetics, candidate genes underlying comb traits are limited. The aim of the study was to use genome-wide association (GWA) studies by 600 K Affymetrix chicken SNP arrays to detect genes that are related to comb, using an F2 resource population. For all comb characters, comb exhibited high SNP-based heritability estimates (0.61–0.69). Chromosome 1 explained 20.80% genetic variance, while chromosome 4 explained 6.89%. Independent univariate genome-wide screens for each character identified 127, 197, and 268 novel significant SNPs with CL, CH, and CW, respectively. Three candidate genes, VPS36, AR, and WNT11B, were determined to have a plausible function in all comb characters. These genes are important to the initiation of follicle development, gonadal growth, and dermal development, respectively. The current study provides the first GWA analysis for comb traits. Identification of the genetic basis as well as promising candidate genes will help us understand the underlying genetic architecture of comb development and has practical significance in breeding programs for the selection of comb as an index for sexual maturity or reproduction. PMID:27427764

  14. Genome-Wide Association Studies for Comb Traits in Chickens.

    PubMed

    Shen, Manman; Qu, Liang; Ma, Meng; Dou, Taocun; Lu, Jian; Guo, Jun; Hu, Yuping; Yi, Guoqiang; Yuan, Jingwei; Sun, Congjiao; Wang, Kehua; Yang, Ning

    2016-01-01

    The comb, as a secondary sexual character, is an important trait in chicken. Indicators of comb length (CL), comb height (CH), and comb weight (CW) are often selected in production. DNA-based marker-assisted selection could help chicken breeders to accelerate genetic improvement for comb or related economic characters by early selection. Although a number of quantitative trait loci (QTL) and candidate genes have been identified with advances in molecular genetics, candidate genes underlying comb traits are limited. The aim of the study was to use genome-wide association (GWA) studies by 600 K Affymetrix chicken SNP arrays to detect genes that are related to comb, using an F2 resource population. For all comb characters, comb exhibited high SNP-based heritability estimates (0.61-0.69). Chromosome 1 explained 20.80% genetic variance, while chromosome 4 explained 6.89%. Independent univariate genome-wide screens for each character identified 127, 197, and 268 novel significant SNPs with CL, CH, and CW, respectively. Three candidate genes, VPS36, AR, and WNT11B, were determined to have a plausible function in all comb characters. These genes are important to the initiation of follicle development, gonadal growth, and dermal development, respectively. The current study provides the first GWA analysis for comb traits. Identification of the genetic basis as well as promising candidate genes will help us understand the underlying genetic architecture of comb development and has practical significance in breeding programs for the selection of comb as an index for sexual maturity or reproduction. PMID:27427764

  15. Mesoscopic description of random walks on combs.

    PubMed

    Méndez, Vicenç; Iomin, Alexander; Campos, Daniel; Horsthemke, Werner

    2015-12-01

    Combs are a simple caricature of various types of natural branched structures, which belong to the category of loopless graphs and consist of a backbone and branches. We study continuous time random walks on combs and present a generic method to obtain their transport properties. The random walk along the branches may be biased, and we account for the effect of the branches by renormalizing the waiting time probability distribution function for the motion along the backbone. We analyze the overall diffusion properties along the backbone and find normal diffusion, anomalous diffusion, and stochastic localization (diffusion failure), respectively, depending on the characteristics of the continuous time random walk along the branches, and compare our analytical results with stochastic simulations. PMID:26764637

  16. Mesoscopic description of random walks on combs

    NASA Astrophysics Data System (ADS)

    Méndez, Vicenç; Iomin, Alexander; Campos, Daniel; Horsthemke, Werner

    2015-12-01

    Combs are a simple caricature of various types of natural branched structures, which belong to the category of loopless graphs and consist of a backbone and branches. We study continuous time random walks on combs and present a generic method to obtain their transport properties. The random walk along the branches may be biased, and we account for the effect of the branches by renormalizing the waiting time probability distribution function for the motion along the backbone. We analyze the overall diffusion properties along the backbone and find normal diffusion, anomalous diffusion, and stochastic localization (diffusion failure), respectively, depending on the characteristics of the continuous time random walk along the branches, and compare our analytical results with stochastic simulations.

  17. Radiation comb generation with extended Josephson junctions

    SciTech Connect

    Solinas, P.; Bosisio, R.; Giazotto, F.

    2015-09-21

    We propose the implementation of a Josephson radiation comb generator based on an extended Josephson junction subject to a time dependent magnetic field. The junction critical current shows known diffraction patterns and determines the position of the critical nodes when it vanishes. When the magnetic flux passes through one of such critical nodes, the superconducting phase must undergo a π-jump to minimize the Josephson energy. Correspondingly, a voltage pulse is generated at the extremes of the junction. Under periodic driving, this allows us to produce a comb-like voltage pulses sequence. In the frequency domain, it is possible to generate up to hundreds of harmonics of the fundamental driving frequency, thus mimicking the frequency comb used in optics and metrology. We discuss several implementations through a rectangular, cylindrical, and annular junction geometries, allowing us to generate different radiation spectra and to produce an output power up to 10 pW at 50 GHz for a driving frequency of 100 MHz.

  18. Frequency-agile dual-comb spectroscopy

    NASA Astrophysics Data System (ADS)

    Millot, Guy; Pitois, Stéphane; Yan, Ming; Hovhannisyan, Tatevik; Bendahmane, Abdelkrim; Hänsch, Theodor W.; Picqué, Nathalie

    2016-01-01

    Spectroscopic gas sensing and its applications to, for example, trace detection or chemical kinetics, require ever more demanding measurement times, acquisition rates, sensitivities, precisions and broad tuning ranges. Here, we propose a new approach to near-infrared molecular spectroscopy, utilizing advanced concepts of optical telecommunications and supercontinuum photonics. We generate, without mode-locked lasers, two frequency combs of slightly different repetition frequencies and moderate, but rapidly tunable, spectral span. The output of a frequency-agile continuous-wave laser is split and sent into two electro-optic intensity modulators. Flat-top low-noise frequency combs are produced by wave-breaking in a nonlinear optical fibre of normal dispersion. With a dual-comb spectrometer, we record Doppler-limited spectra spanning 60 GHz within 13 μs and an 80 kHz refresh rate, at a tuning speed of 10 nm s-1. The sensitivity for weak absorption is enhanced by a long gas-filled hollow-core fibre. New opportunities for real-time diagnostics may be opened up, even outside the laboratory.

  19. Optical study of narrow band gap InAsxSb1 -x (x =0 , 0.25, 0.5, 0.75, 1) alloys

    NASA Astrophysics Data System (ADS)

    Namjoo, Shirin; Rozatian, Amir S. H.; Jabbari, Iraj; Puschnig, Peter

    2015-05-01

    The structural, electronic, and optical properties of InAs, InSb, and their ternary alloys InAsxSb1 -x (x =0.25 , 0.5, 0.75) are investigated within density functional theory utilizing the wien2k package. We find that the lattice constants and bulk moduli as a function of x are in best agreement with Vegard's linear rule. When computing the electronic band structures with the modified Becke-Johnson exchange-correlation functional (mBJLDA), our results for the band gaps of InAs, InSb, and their ternary alloys are in good agreement with the available experimental results while the conventional Wu-Cohen generalized gradient approximation (GGA) functional leads to zero or close to zero band gaps. In particular, our mBJLDA results confirm experimental evidence that the minimum band gap occurs for As concentrations around x ≈0.3 . Furthermore, we investigate the dielectric function of these compounds within the random phase approximation using both the Wu-Cohen GGA and the mBJLDA functionals. While the mBJLDA results of our fully first-principles calculations show good agreement of the peak positions in ɛ2(ω ) with experiments, the peaks in the optical spectra based on the Wu-Cohen GGA band structure appear redshifted compared to experiment. We further identify the interband transitions responsible for the structures in the spectra. Looking at the optical matrix element, we note that the major peaks are dominated by transition from the Sb 5 p (As 4 p ) states to In s states for InSb and InAs0.25Sb0.75 (InAs, InAs0.75Sb0.25 , and InAs0.5Sb0.5 ).

  20. Demonstration of optical multicasting using Kerr frequency comb lines.

    PubMed

    Bao, Changjing; Liao, Peicheng; Kordts, Arne; Karpov, Maxim; Pfeiffer, Martin H P; Zhang, Lin; Yan, Yan; Xie, Guodong; Cao, Yinwen; Almaiman, Ahmed; Ziyadi, Morteza; Li, Long; Zhao, Zhe; Mohajerin-Ariaei, Amirhossein; Wilkinson, Steven R; Tur, Moshe; Fejer, Martin M; Kippenberg, Tobias J; Willner, Alan E

    2016-08-15

    We experimentally demonstrate optical multicasting using Kerr frequency combs generated from a Si3N4 microresonator. We obtain Kerr combs in two states with different noise properties by varying the pump wavelength in the resonator and investigate the effect of Kerr combs on multicasting. Seven-fold multicasting of 20 Gbaud quadrature phase-shift-keyed signals and four-fold multicasting of 16-quadrature amplitude modulation signals have been achieved when low-phase-noise combs are input into a periodically poled lithium niobate waveguide. In addition, we find that the wavelength conversion efficiency in the PPLN waveguide for chaotic combs with high noise is similar to that for low-noise combs, while the signal quality of the multicast copy is significantly degraded. PMID:27519112

  1. Recent advances in ultrafast optical parametric oscillator frequency combs

    NASA Astrophysics Data System (ADS)

    McCracken, Richard A.; Zhang, Zhaowei; Reid, Derryck T.

    2014-12-01

    We discuss recent advances in the stabilization and application of femtosecond frequency combs based on optical parametric oscillators (OPOs) pumped by femtosecond lasers at 800 and 1060 nm. A method for locking to zero the carrier-envelope-offset of a Ti:sapphire-pumped OPO comb is described. The application of Yb:KYW-laser-pumped dual-combs for mid-infrared spectroscopy is detailed, specifically methane spectroscopy at approximately a 0.7% concentration at 1 atm.

  2. Thermally controlled comb generation and soliton modelocking in microresonators

    NASA Astrophysics Data System (ADS)

    Joshi, Chaitanya; Jang, Jae K.; Luke, Kevin; Ji, Xingchen; Miller, Steven A.; Klenner, Alexander; Okawachi, Yoshitomo; Lipson, Michal; Gaeta, Alexander L.

    2016-06-01

    We report the first demonstration of thermally controlled soliton modelocked frequency comb generation in microresonators. By controlling the electric current through heaters integrated with silicon nitride microresonators, we demonstrate a systematic and repeatable pathway to single- and multi-soliton modelocked states without adjusting the pump laser wavelength. Such an approach could greatly simplify the generation of modelocked frequency combs and facilitate applications such as chip-based dual-comb spectroscopy.

  3. Microresonator-based comb generation without an external laser source.

    PubMed

    Johnson, Adrea R; Okawachi, Yoshitomo; Lamont, Michael R E; Levy, Jacob S; Lipson, Michal; Gaeta, Alexander L

    2014-01-27

    We demonstrate a fiber-microresonator dual-cavity architecture with which we generate 880 nm of comb bandwidth without the need for a continuous-wave pump laser. Comb generation with this pumping scheme is greatly simplified as compared to pumping with a single frequency laser, and the generated combs are inherently robust due to the intrinsic feedback mechanism. Temporal and radio frequency (RF) characterization show a regime of steady comb formation that operates with reduced RF amplitude noise. The dual-cavity design is capable of being integrated on-chip and offers the potential of a turn-key broadband multiple wavelength source. PMID:24515147

  4. Wet combing for the eradication of head lice.

    PubMed

    2013-03-01

    Manual removal (using conditioner and comb or a wet comb) can be used in the treatment of head lice. Head lice infestation (Pediculosis humanus capitis) is a common problem. It is diagnosed by visualising the lice. As half of people infested with head lice will not scratch, all people in contact with a person affected with head lice should be manually checked for infestations. Wet combing is easily and safely performed at home, but persistence is needed. This article describes the process of head lice removal using a wet comb. It has NHMRC Level 2 evidence of efficacy and no serious adverse effects have been reported. PMID:23529522

  5. Frequency comb from a microresonator with engineered spectrum.

    PubMed

    Grudinin, Ivan S; Baumgartel, Lukas; Yu, Nan

    2012-03-12

    We demonstrate that by varying the ratio between the linewidth and dispersion of a whispering gallery mode resonator we are able to control the number N of free spectral ranges separating the first generated comb sidebands from the pump. We observed combs with N = 19 and N = 1. For the comb with N = 1 we have achieved a span of over 200 nm using a 0.4 mm MgF₂ resonator pumped with 50 mW at 1560 nm. This pump power is a factor of 10 lower than previously reported for combs with comparable bandwidth. PMID:22418543

  6. Dual-comb spectroscopy with a phase-modulated probe comb for sub-MHz spectral sampling.

    PubMed

    Hébert, Nicolas Bourbeau; Michaud-Belleau, Vincent; Magnan-Saucier, Sébastien; Deschênes, Jean-Daniel; Genest, Jérôme

    2016-05-15

    We present a straightforward and efficient method to reduce the mode spacing of a frequency comb based on binary pseudo-random phase modulation of its pulse train. As a proof of concept, we use such a densified comb to perform dual-comb spectroscopy of a long-delay Mach-Zehnder interferometer and a high-quality-factor microresonator with sub-MHz spectral sampling. Since this approach is based on binary phase modulation, it combines all the advantages of other densification techniques: simplicity, single-step implementation, and conservation of the initial comb's power. PMID:27176983

  7. Integrated Photonic Comb Generation: Applications in Coherent Communication and Sensing

    NASA Astrophysics Data System (ADS)

    Parker, John S.

    Integrated photonics combines many optical components including lasers, modulators, waveguides, and detectors in close proximity via homogeneous (monolithic) or heterogeneous (using multiple materials) integration. This improves stability for interferometers and lasers, reduces the occurrence of unwanted reflections, and it avoids coupling losses between different components as they are on the same chip. Thus, less power is needed to compensate for these added losses, and less heat needs to be removed due to these power savings. In addition, integration allows the many components that comprise a system to be fabricated together, thereby reducing the cost per system and allowing rapid scaling in production throughput. Integrated optical combs have many applications including: metrology, THz frequency generation, arbitrary waveform generation, optical clocks, photonic analog-to-digital converters, sensing (imaging), spectroscopy, and data communication. A comb is a set of optical sources evenly spaced in frequency. Several methods of comb generation including mode-locking and optical parametric oscillation produce phase-matched optical outputs with a fixed phase relationship between the frequency lines. When the absolute frequency of a single comb line is stabilized along with the frequency spacing between comb lines, absolute phase and frequency precision can be achieved over the entire comb bandwidth. This functionality provides tremendous benefits to many applications such as coherent communication and optical sensing. The goals for this work were achieving a broad comb bandwidth and noise reduction, i.e., frequency and phase stability. Integrated mode-locked lasers on the InGaAsP/InP material platform were chosen, as they could be monolithically integrated with the wide range of highly functional and versatile photonic integrated circuits (PICs) previously demonstrated on this platform at UCSB. Gain flattening filters were implemented to increase the comb

  8. Photonic generation of linearly chirped millimeter wave based on comb-spacing tunable optical frequency comb

    NASA Astrophysics Data System (ADS)

    Xia, Zongyang; Xie, Weilin; Sun, Dongning; Shi, Hongxiao; Dong, Yi; Hu, Weisheng

    2013-12-01

    We demonstrated a photonic approach to generate a phase-continuous frequency-linear-chirped millimeter-wave (mm-wave) signal with high linearity based on continuous-wave phase modulated optical frequency comb and cascaded interleavers. Through linearly sweeping the frequency of the radio frequency (RF) driving signal, high-order frequency-linear-chirped optical comb lines are generated and then extracted by the cascaded interleavers. By beating the filtered high-order comb lines, center frequency and chirp range multiplied linear-chirp microwave signals are generated. Frequency doubled and quadrupled linear-chirp mm-wave signals of range 48.6 to 52.6 GHz and 97.2 to 105.2 GHz at chirp rates of 133.33 and 266.67 GHz/s are demonstrated with the ±1st and ±2nd optical comb lines, respectively, while the RF driving signal is of chirp range 24.3 to 26.3 GHz and chirp time 30 ms.

  9. Spectrally interleaved, comb-mode-resolved spectroscopy using swept dual terahertz combs

    PubMed Central

    Hsieh, Yi-Da; Iyonaga, Yuki; Sakaguchi, Yoshiyuki; Yokoyama, Shuko; Inaba, Hajime; Minoshima, Kaoru; Hindle, Francis; Araki, Tsutomu; Yasui, Takeshi

    2014-01-01

    Optical frequency combs are innovative tools for broadband spectroscopy because a series of comb modes can serve as frequency markers that are traceable to a microwave frequency standard. However, a mode distribution that is too discrete limits the spectral sampling interval to the mode frequency spacing even though individual mode linewidth is sufficiently narrow. Here, using a combination of a spectral interleaving and dual-comb spectroscopy in the terahertz (THz) region, we achieved a spectral sampling interval equal to the mode linewidth rather than the mode spacing. The spectrally interleaved THz comb was realized by sweeping the laser repetition frequency and interleaving additional frequency marks. In low-pressure gas spectroscopy, we achieved an improved spectral sampling density of 2.5 MHz and enhanced spectral accuracy of 8.39 × 10−7 in the THz region. The proposed method is a powerful tool for simultaneously achieving high resolution, high accuracy, and broad spectral coverage in THz spectroscopy. PMID:24448604

  10. Efficiency optimization for atomic frequency comb storage

    SciTech Connect

    Bonarota, M.; Ruggiero, J.; Le Goueet, J.-L.; Chaneliere, T.

    2010-03-15

    We study the efficiency of the atomic frequency comb storage protocol. We show that for a given optical depth, the preparation procedure can be optimize to significantly improve the retrieval. Our prediction is well supported by the experimental implementation of the protocol in a Tm{sup 3+}:YAG crystal. We observe a net gain in efficiency from 10 to 17% by applying the optimized preparation procedure. In the perspective of high bandwidth storage, we investigate the protocol under different magnetic fields. We analyze the effect of the Zeeman and superhyperfine interaction.

  11. Superdiffusion of cancer on a comb structure

    NASA Astrophysics Data System (ADS)

    Iomin, Alexander

    2005-01-01

    The influence of cell fission on transport properties of the vessel network is studied. A simple mathematical model is proposed by virtue of heuristic arguments on tumor development. The constructed model is a modification of a so-called comb structure. In the framework of this model we are able to show that the tumor development corresponds to fractional transport of cells. A possible answer to the question how the malignant neoplasm cells appear at an arbitrary distance from the primary tumor is proposed. The model could also be a possible mechanism for diffusive cancers.

  12. Dislocations in mismatched layers of GaAsxP1 - x in between GaP as observed by low-temperature cathodoluminescence: Part I. Grown on (001) oriented substrates.

    NASA Astrophysics Data System (ADS)

    Gustafsson, A.; Pistol, M.-E.; Gerling, M.; Samuelson, L.; Leys, M. R.; Titze, H.

    1991-08-01

    The possibility of growing lattice-mismatched layers and quantum wells becomes more and more interesting for the fabrication of devices. For device performance it is necessary to control the formation of misfit dislocations within the mismatched layers. It is therefore essential to study the onset of misfit dislocations versus amount of mismatch and layer thickness. A preliminary cathodoluminescence (CL) investigation, performed on layers of GaAsxP1-x mismatched to GaP barriers, was presented [A. Gustafsson, J. Jönsson, M. Gerling, M. R. Leys, M.-E. Pistol, L. Samuelson, and H. Titze, Inst. Phys. Conf. Ser. No 100, 771 (1989)]. In this paper the critical thickness with respect to the composition, x, in GaAsxP1-x, is studied from a determination of the onset of the formation of dislocations as observed in the monochromatic CL images. The experimental values of the critical thickness are compared to theoretical predictions for the critical thickness, according to different theories. The best agreement is found with the mechanical equilibrium theory, which assumes that the barrier for the formation of dislocations is negligible.

  13. Coherent Raman dual-comb spectroscopy and imaging

    NASA Astrophysics Data System (ADS)

    Ideguchi, Takuro; Holzner, Simon; Bernhardt, Birgitta; Guelachvili, Guy; Hänsch, Theodor W.; Picqué, Nathalie

    2014-11-01

    The invention of the optical frequency comb technique has revolutionized the field of precision spectroscopy, providing a way to measure the absolute frequency of any optical transition. Since, frequency combs have become common equipment for frequency metrology. In the last decade, novel applications for the optical frequency comb have been demonstrated beyond its original purpose. Broadband molecular spectroscopy is one of those. One such technique of molecular spectroscopy with frequency combs, dual-comb Fourier transform spectroscopy provides short measurement times with resolution and accuracy. Two laser frequency combs with slightly different repetition frequencies generate pairs of pulses with a linearly-scanned delay between pulses in a pair. The system without moving parts mimics a fast scanning Fourier transform interferometer. The measurement speed may be several orders of magnitude faster than that of a Michelson-based Fourier transform spectrometer, which opens up new opportunities for broadband molecular spectroscopy. Recently, dual-comb spectroscopy has been extended to nonlinear phenomena. A broadband Raman spectrum of molecular fingerprints may be measured within a few tens of microseconds with coherent Raman dual-comb spectroscopy. Raster scanning the sample leads to hyperspectral images. This rapid and broadband label-free vibrational spectroscopy and imaging technique might provide new diagnostic methods in a variety of scientific and industrial fields.

  14. Dynamics of microresonator frequency comb generation: models and stability

    NASA Astrophysics Data System (ADS)

    Hansson, Tobias; Wabnitz, Stefan

    2016-06-01

    Microresonator frequency combs hold promise for enabling a new class of light sources that are simultaneously both broadband and coherent, and that could allow for a profusion of potential applications. In this article, we review various theoretical models for describing the temporal dynamics and formation of optical frequency combs. These models form the basis for performing numerical simulations that can be used in order to better understand the comb generation process, for example helping to identify the universal combcharacteristics and their different associated physical phenomena. Moreover, models allow for the study, design and optimization of comb properties prior to the fabrication of actual devices. We consider and derive theoretical formalisms based on the Ikeda map, the modal expansion approach, and the Lugiato-Lefever equation. We further discuss the generation of frequency combs in silicon resonators featuring multiphoton absorption and free-carrier effects. Additionally, we review comb stability properties and consider the role of modulational instability as well as of parametric instabilities due to the boundary conditions of the cavity. These instability mechanisms are the basis for comprehending the process of frequency comb formation, for identifying the different dynamical regimes and the associated dependence on the comb parameters. Finally, we also discuss the phenomena of continuous wave bi- and multistability and its relation to the observation of mode-locked cavity solitons.

  15. Dual-Comb Spectroscopy in the Open Air

    NASA Astrophysics Data System (ADS)

    Rieker, Greg B.; Klose, Andrew; Diddams, Scott; Coddington, Ian; Giorgetta, Fabrizio; Sinclair, Laura; Baumann, Esther; Truong, Gar-Wing; Ycas, Gabriel; Swann, William C.; Newbury, Nathan R.

    2015-06-01

    Dual-comb spectroscopy is arguably the natural successor to FTIR. Based on the interference between two frequency combs, this technique can record broadband spectra with a resolution better than 0.0003 wn. Like FTIR, dual-comb spectroscopy measures an entire spectrum simultaneously, allowing for suppression of systematic errors related to temporal dynamics of the sample. Unlike FTIR it records the entire spectrum with virtually no instrument lineshape or error in the frequency axis. The lack of moving parts in dual-comb spectroscopy means that spectra can be recorded in milliseconds to microseconds with the desired signal-to-noise being the only real constrain on the minimum recording time. Finally the high spacial beam quality of the frequency combs allows for increased sensitivity through long interaction paths either in free-space, multi-pass cells or enhancement cavities. This talk will explore the recent use of dual-comb spectroscopy in the near-infrared to measure atmospheric carbon dioxide, methane and water concentrations over a 2-km outdoor open-air path. Due to many of the strengths just mentioned, precisions of <1 ppm for CO_2 and <3 ppb for CH_4 in 5 min are achieved making this system very attractive for carbon monitoring at length scales relevant to carbon transport models. Additionally this presentation will address recent work on robust, compact, and portable dual-comb spectrometers as well as dual-comb spectroscopy further into the IR.

  16. Comparative analysis of spectral coherence in microresonator frequency combs.

    PubMed

    Torres-Company, Victor; Castelló-Lurbe, David; Silvestre, Enrique

    2014-02-24

    Microresonator combs exploit parametric oscillation and nonlinear mixing in an ultrahigh-Q cavity. This new comb generator offers unique potential for chip integration and access to high repetition rates. However, time-domain studies reveal an intricate spectral coherence behavior in this type of platform. In particular, coherent, partially coherent or incoherent combs have been observed using the same microresonator under different pumping conditions. In this work, we provide a numerical analysis of the coherence dynamics that supports the above experimental findings and verify particular design rules to achieve spectrally coherent microresonator combs. A particular emphasis is placed in understanding the differences between so-called Type I and Type II combs. PMID:24663786

  17. Theory and applications of sampled analog recursive CTD comb filters

    NASA Technical Reports Server (NTRS)

    Tao, T. F.; Holmes, S. V.; Ejaz, A.; Piazza, F.; Saetre, L. T.; Freund, B.

    1976-01-01

    Sampled analog comb filter using a recursive filter implementation was studied. Charge transfer device delay lines were used as the delay elements. The similarities and differences between sampled analog recursive filter and digital recursive filter were pointed out. Both canceller type and integrator type comb filter using the first order or the second order canonical circuits were studied. Experimental results of frequency response are presented to show their difference from that of digital filters. A theoretical analysis was presented based essentially on the digital filter theory but modified to take into account the differences described above. The usefulness of this theory in analyzing the comb filter characteristics was discussed. Several applications of both the canceller type comb filter and the integrator type comb filter were demonstrated.

  18. Does combing the scalp reduce scalp electrode impedances?

    PubMed

    Mahajan, Yatin; McArthur, Genevieve

    2010-05-15

    Electrical activity from the human brain can be recorded via electrodes on the scalp. It is important to reduce the impedance of each electrode to minimize unwanted noise in the recording. Electrode impedance can be improved by abrading the skin to remove dead skin cells. In this experiment, we tested if abrading the skin by combing the scalp leads to a significant reduction in electrode impedance. We compared the mean electrode impedance values of 20 subjects whose scalps were combed prior to electrode cap placement, with 20 subjects whose scalps were not combed. Combing significantly reduced the impedances at central, right, and left areas of the scalp. This finding supports the use of scalp combing to reduce the time and subject discomfort that can be associated with placing scalp electrodes. This is particularly important for experiments testing children. PMID:20211649

  19. Cavity-Enhanced Optical Frequency Comb Spectroscopy

    NASA Astrophysics Data System (ADS)

    Ye, Jun; Thorpe, Michael J.; Adler, Florian; Cossel, Kevin C.

    2009-06-01

    Cavity-enhanced optical frequency comb spectroscopy is a new technique that realizes simultaneously broad spectral coverage and high spectral resolution provided by an optical frequency comb as well as ultrahigh detection sensitivities enabled with a high-finesse optical cavity [1]. These powerful capabilities have been demonstrated in a series of experiments where real-time detection and identification of many different molecular states or species are achieved in a massively parallel fashion [2,3]. We will discuss the principle, technical requirements, and various implementations for this spectroscopic approach, as well as applications that include trace gas detections, human breath analysis, and characterization of cold and ultracold molecules [4,5,6]. References: [1] M. J. Thorpe, K. D. Moll, B. Safdi, and J. Ye, Science 311, 1595 (2006). [2] M. J. Thorpe, D. D. Hudson, K. D. Moll, J. Lasri, and J. Ye, Opt. Lett. 32, 307 (2007). [3] C. Gohle, B. Stein, A. Schliesser, T. Udem, and T. W. Hänsch, Phys. Rev. Lett. 99, 263902 (2007). [4] M. J. Thorpe, D. Balslev-Clausen, M. Kirchner, and J. Ye, Opt. Express. 16, 2387 (2008). [5] M. J. Thorpe and J. Ye, Appl. Phys. B 91, 397 (2008). [6] M. J. Thorpe, F. Adler, K. C. Cossel, M. H. G. de Miranda, and J. Ye, Chem. Phys. Lett. 468, 1 (2009).

  20. Comb-locked Lamb-dip spectrometer

    PubMed Central

    Gatti, Davide; Gotti, Riccardo; Gambetta, Alessio; Belmonte, Michele; Galzerano, Gianluca; Laporta, Paolo; Marangoni, Marco

    2016-01-01

    Overcoming the Doppler broadening limit is a cornerstone of precision spectroscopy. Nevertheless, the achievement of a Doppler-free regime is severely hampered by the need of high field intensities to saturate absorption transitions and of a high signal-to-noise ratio to detect tiny Lamb-dip features. Here we present a novel comb-assisted spectrometer ensuring over a broad range from 1.5 to 1.63 μm intra-cavity field enhancement up to 1.5 kW/cm2, which is suitable for saturation of transitions with extremely weak electric dipole moments. Referencing to an optical frequency comb allows the spectrometer to operate with kHz-level frequency accuracy, while an extremely tight locking of the probe laser to the enhancement cavity enables a 10−11 cm−1 absorption sensitivity to be reached over 200 s in a purely dc direct-detection-mode at the cavity output. The particularly simple and robust detection and operating scheme, together with the wide tunability available, makes the system suitable to explore thousands of lines of several molecules never observed so far in a Doppler-free regime. As a demonstration, Lamb-dip spectroscopy is performed on the P(15) line of the 01120-00000 band of acetylene, featuring a line-strength below 10−23 cm/mol and an Einstein coefficient of 5 mHz, among the weakest ever observed. PMID:27263858

  1. Comb-locked Lamb-dip spectrometer.

    PubMed

    Gatti, Davide; Gotti, Riccardo; Gambetta, Alessio; Belmonte, Michele; Galzerano, Gianluca; Laporta, Paolo; Marangoni, Marco

    2016-01-01

    Overcoming the Doppler broadening limit is a cornerstone of precision spectroscopy. Nevertheless, the achievement of a Doppler-free regime is severely hampered by the need of high field intensities to saturate absorption transitions and of a high signal-to-noise ratio to detect tiny Lamb-dip features. Here we present a novel comb-assisted spectrometer ensuring over a broad range from 1.5 to 1.63 μm intra-cavity field enhancement up to 1.5 kW/cm(2), which is suitable for saturation of transitions with extremely weak electric dipole moments. Referencing to an optical frequency comb allows the spectrometer to operate with kHz-level frequency accuracy, while an extremely tight locking of the probe laser to the enhancement cavity enables a 10(-11) cm(-1) absorption sensitivity to be reached over 200 s in a purely dc direct-detection-mode at the cavity output. The particularly simple and robust detection and operating scheme, together with the wide tunability available, makes the system suitable to explore thousands of lines of several molecules never observed so far in a Doppler-free regime. As a demonstration, Lamb-dip spectroscopy is performed on the P(15) line of the 01120-00000 band of acetylene, featuring a line-strength below 10(-23) cm/mol and an Einstein coefficient of 5 mHz, among the weakest ever observed. PMID:27263858

  2. Tunable Surface Properties from Bioinspired Comb Copolymers

    NASA Astrophysics Data System (ADS)

    van Zoelen, Wendy; Buss, Hilda; Ellebracht, Nathan; Zuckermann, Ronald; Segalman, Rachel

    2013-03-01

    A modular polymer system which incorporates multiple functionalities simultaneously while keeping an identical backbone chemistry is a useful tool in determining necessary functionalities for marine antifouling properties. We have investigated the surface properties and antifouling behavior of polypeptoids, a class of non-natural biomimetic polymers based on an N-substituted glycine backbone, that combine many of the advantageous properties of bulk polymers with those of synthetically produced proteins, including controllable chain shape, sequence, and self-assembled structure. Using thiol-ene click chemistry, thiol functionalized amphiphilic peptoid sequences consisting of hydrophilic methoxyethyl and hydrophobic heptafluorobutyl side chains were attached to polystyrene-block-poly(ethylene oxide-stat-allyl glycidyl ether), creating comb-shaped molecules. Near edge X-ray absorption fine structure spectroscopy (NEXAFS) was used to study the surface characteristics as a function of peptoid length and composition. Only 20% of fluorinated groups in the peptoid were sufficient for promoting surface display of the otherwise hydrophilic PEO/peptoid comb block. Antifouling experiments with spores of the green algae Ulva indicated an influence of sequence.

  3. Comb-locked Lamb-dip spectrometer

    NASA Astrophysics Data System (ADS)

    Gatti, Davide; Gotti, Riccardo; Gambetta, Alessio; Belmonte, Michele; Galzerano, Gianluca; Laporta, Paolo; Marangoni, Marco

    2016-06-01

    Overcoming the Doppler broadening limit is a cornerstone of precision spectroscopy. Nevertheless, the achievement of a Doppler-free regime is severely hampered by the need of high field intensities to saturate absorption transitions and of a high signal-to-noise ratio to detect tiny Lamb-dip features. Here we present a novel comb-assisted spectrometer ensuring over a broad range from 1.5 to 1.63 μm intra-cavity field enhancement up to 1.5 kW/cm2, which is suitable for saturation of transitions with extremely weak electric dipole moments. Referencing to an optical frequency comb allows the spectrometer to operate with kHz-level frequency accuracy, while an extremely tight locking of the probe laser to the enhancement cavity enables a 10‑11 cm‑1 absorption sensitivity to be reached over 200 s in a purely dc direct-detection-mode at the cavity output. The particularly simple and robust detection and operating scheme, together with the wide tunability available, makes the system suitable to explore thousands of lines of several molecules never observed so far in a Doppler-free regime. As a demonstration, Lamb-dip spectroscopy is performed on the P(15) line of the 01120-00000 band of acetylene, featuring a line-strength below 10‑23 cm/mol and an Einstein coefficient of 5 mHz, among the weakest ever observed.

  4. Silicon-chip mid-infrared frequency comb generation.

    PubMed

    Griffith, Austin G; Lau, Ryan K W; Cardenas, Jaime; Okawachi, Yoshitomo; Mohanty, Aseema; Fain, Romy; Lee, Yoon Ho Daniel; Yu, Mengjie; Phare, Christopher T; Poitras, Carl B; Gaeta, Alexander L; Lipson, Michal

    2015-01-01

    Optical frequency combs are a revolutionary light source for high-precision spectroscopy because of their narrow linewidths and precise frequency spacing. Generation of such combs in the mid-infrared spectral region (2-20 μm) is important for molecular gas detection owing to the presence of a large number of absorption lines in this wavelength regime. Microresonator-based frequency comb sources can provide a compact and robust platform for comb generation that can operate with relatively low optical powers. However, material and dispersion engineering limitations have prevented the realization of an on-chip integrated mid-infrared microresonator comb source. Here we demonstrate a complementary metal-oxide-semiconductor compatible platform for on-chip comb generation using silicon microresonators, and realize a broadband frequency comb spanning from 2.1 to 3.5 μm. This platform is compact and robust and offers the potential to be versatile for use outside the laboratory environment for applications such as real-time monitoring of atmospheric gas conditions. PMID:25708922

  5. Coherent terabit communications with microresonator Kerr frequency combs.

    PubMed

    Pfeifle, Joerg; Brasch, Victor; Lauermann, Matthias; Yu, Yimin; Wegner, Daniel; Herr, Tobias; Hartinger, Klaus; Schindler, Philipp; Li, Jingshi; Hillerkuss, David; Schmogrow, Rene; Weimann, Claudius; Holzwarth, Ronald; Freude, Wolfgang; Leuthold, Juerg; Kippenberg, Tobias J; Koos, Christian

    2014-05-01

    Optical frequency combs have the potential to revolutionize terabit communications(1). Generation of Kerr combs in nonlinear microresonators(2) represents a particularly promising option(3) enabling line spacings of tens of GHz. However, such combs may exhibit strong phase noise(4-6), which has made high-speed data transmission impossible up to now. Here we demonstrate that systematic adjustment of pump conditions for low phase noise(4,7-9) enables coherent data transmission with advanced modulation formats that pose stringent requirements on the spectral purity of the comb. In a first experiment, we encode a data stream of 392 Gbit/s on a Kerr comb using quadrature phase shift keying (QPSK) and 16-state quadrature amplitude modulation (16QAM). A second experiment demonstrates feedback-stabilization of the comb and transmission of a 1.44 Tbit/s data stream over up to 300 km. The results show that Kerr combs meet the highly demanding requirements of coherent communications and thus offer an attractive solution towards chip-scale terabit/s transceivers. PMID:24860615

  6. Coherent terabit communications with microresonator Kerr frequency combs

    PubMed Central

    Pfeifle, Joerg; Brasch, Victor; Lauermann, Matthias; Yu, Yimin; Wegner, Daniel; Herr, Tobias; Hartinger, Klaus; Schindler, Philipp; Li, Jingshi; Hillerkuss, David; Schmogrow, Rene; Weimann, Claudius; Holzwarth, Ronald; Freude, Wolfgang; Leuthold, Juerg; Kippenberg, Tobias J.; Koos, Christian

    2014-01-01

    Optical frequency combs have the potential to revolutionize terabit communications1. Generation of Kerr combs in nonlinear microresonators2 represents a particularly promising option3 enabling line spacings of tens of GHz. However, such combs may exhibit strong phase noise4-6, which has made high-speed data transmission impossible up to now. Here we demonstrate that systematic adjustment of pump conditions for low phase noise4,7-9 enables coherent data transmission with advanced modulation formats that pose stringent requirements on the spectral purity of the comb. In a first experiment, we encode a data stream of 392 Gbit/s on a Kerr comb using quadrature phase shift keying (QPSK) and 16-state quadrature amplitude modulation (16QAM). A second experiment demonstrates feedback-stabilization of the comb and transmission of a 1.44 Tbit/s data stream over up to 300 km. The results show that Kerr combs meet the highly demanding requirements of coherent communications and thus offer an attractive solution towards chip-scale terabit/s transceivers. PMID:24860615

  7. Frequency comb metrology with an optical parametric oscillator.

    PubMed

    Balskus, K; Schilt, S; Wittwer, V J; Brochard, P; Ploetzing, T; Jornod, N; McCracken, R A; Zhang, Z; Bartels, A; Reid, D T; Südmeyer, T

    2016-04-18

    We report on the first demonstration of absolute frequency comb metrology with an optical parametric oscillator (OPO) frequency comb. The synchronously-pumped OPO operated in the 1.5-µm spectral region and was referenced to an H-maser atomic clock. Using different techniques, we thoroughly characterized the frequency noise power spectral density (PSD) of the repetition rate frep, of the carrier-envelope offset frequency fCEO, and of an optical comb line νN. The comb mode optical linewidth at 1557 nm was determined to be ~70 kHz for an observation time of 1 s from the measured frequency noise PSD, and was limited by the stability of the microwave frequency standard available for the stabilization of the comb repetition rate. We achieved a tight lock of the carrier envelope offset frequency with only ~300 mrad residual integrated phase noise, which makes its contribution to the optical linewidth negligible. The OPO comb was used to measure the absolute optical frequency of a near-infrared laser whose second-harmonic component was locked to the F = 2→3 transition of the 87Rb D2 line at 780 nm, leading to a measured transition frequency of νRb = 384,228,115,346 ± 16 kHz. We performed the same measurement with a commercial fiber-laser comb operating in the 1.5-µm region. Both the OPO comb and the commercial fiber comb achieved similar performance. The measurement accuracy was limited by interferometric noise in the fibered setup of the Rb-stabilized laser. PMID:27137274

  8. Comb entanglement in quantum spin chains

    SciTech Connect

    Keating, J. P.; Mezzadri, F.; Novaes, M.

    2006-07-15

    Bipartite entanglement in the ground state of a chain of N quantum spins can be quantified either by computing pairwise concurrence or by dividing the chain into two complementary subsystems. In the latter case the smaller subsystem is usually a single spin or a block of adjacent spins and the entanglement differentiates between critical and noncritical regimes. Here we extend this approach by considering a more general setting: our smaller subsystem S{sub A} consists of a comb of L spins, spaced p sites apart. Our results are thus not restricted to a simple area law, but contain nonlocal information, parametrized by the spacing p. For the XX model we calculate the von Neumann entropy analytically when N{yields}{infinity} and investigate its dependence on L and p. We find that an external magnetic field induces an unexpected length scale for entanglement in this case.

  9. Sensitivity of coherent dual-comb spectroscopy.

    PubMed

    Newbury, Nathan R; Coddington, Ian; Swann, William

    2010-04-12

    Coherent dual comb spectroscopy can provide high-resolution, high-accuracy measurements of a sample response in both magnitude and phase. We discuss the achievable signal-to-noise ratio (SNR) due to both additive white noise and multiplicative noise, and the corresponding sensitivity limit for trace gas detection. We show that sequential acquisition of the overall spectrum through a tunable filter, or parallel acquisition of the overall spectrum through a detector array, can significantly improve the SNR under some circumstances. We identify a useful figure of merit as the quality factor, equal to the product of the SNR, normalized by the square root of the acquisition time, and the number of resolved frequency elements. For a single detector and fiber-laser based system, this quality factor is 10(6) - 10(7) Hz(1/2). PMID:20588636

  10. Phase Stabilization of a Frequency Comb using Multipulse Quantum Interferometry

    NASA Astrophysics Data System (ADS)

    Cadarso, Andrea; Mur-Petit, Jordi; García-Ripoll, Juan José

    2014-02-01

    From the interaction between a frequency comb and an atomic qubit, we derive quantum protocols for the determination of the carrier-envelope offset phase, using the qubit coherence as a reference, and without the need of frequency doubling or an octave spanning comb. Compared with a trivial interference protocol, the multipulse protocol results in a polynomial enhancement of the sensitivity O(N-2) with the number N of laser pulses involved. We specialize the protocols using optical or hyperfine qubits, Λ schemes, and Raman transitions, and introduce methods where the reference is another phase-stable cw laser or frequency comb.

  11. Third-order chromatic dispersion stabilizes Kerr frequency combs.

    PubMed

    Parra-Rivas, Pedro; Gomila, Damià; Leo, François; Coen, Stéphane; Gelens, Lendert

    2014-05-15

    Using numerical simulations of an extended Lugiato-Lefever equation we analyze the stability and nonlinear dynamics of Kerr frequency combs generated in microresonators and fiber resonators, taking into account third-order dispersion effects. We show that cavity solitons underlying Kerr frequency combs, normally sensitive to oscillatory and chaotic instabilities, are stabilized in a wide range of parameter space by third-order dispersion. Moreover, we demonstrate how the snaking structure organizing compound states of multiple cavity solitons is qualitatively changed by third-order dispersion, promoting an increased stability of Kerr combs underlined by a single cavity soliton. PMID:24978250

  12. Thermally controlled comb generation and soliton modelocking in microresonators.

    PubMed

    Joshi, Chaitanya; Jang, Jae K; Luke, Kevin; Ji, Xingchen; Miller, Steven A; Klenner, Alexander; Okawachi, Yoshitomo; Lipson, Michal; Gaeta, Alexander L

    2016-06-01

    We report, to the best of our knowledge, the first demonstration of thermally controlled soliton mode-locked frequency comb generation in microresonators. By controlling the electric current through heaters integrated with silicon nitride microresonators, we demonstrate a systematic and repeatable pathway to single- and multi-soliton mode-locked states without adjusting the pump laser wavelength. Such an approach could greatly simplify the generation of mode-locked frequency combs and facilitate applications such as chip-based dual-comb spectroscopy. PMID:27244415

  13. Phase stabilization of a frequency comb using multipulse quantum interferometry.

    PubMed

    Cadarso, Andrea; Mur-Petit, Jordi; García-Ripoll, Juan José

    2014-02-21

    From the interaction between a frequency comb and an atomic qubit, we derive quantum protocols for the determination of the carrier-envelope offset phase, using the qubit coherence as a reference, and without the need of frequency doubling or an octave spanning comb. Compared with a trivial interference protocol, the multipulse protocol results in a polynomial enhancement of the sensitivity O(N-2) with the number N of laser pulses involved. We specialize the protocols using optical or hyperfine qubits, Λ schemes, and Raman transitions, and introduce methods where the reference is another phase-stable cw laser or frequency comb. PMID:24579598

  14. Combing gravitational hair in 2 + 1 dimensions

    NASA Astrophysics Data System (ADS)

    Donnelly, William; Marolf, Donald; Mintun, Eric

    2016-01-01

    The gravitational Gauss law requires any addition of energy to be accompanied by the addition of gravitational flux. The possible configurations of this flux for a given source may be called gravitational hair, and several recent works discuss gravitational observables (‘gravitational Wilson lines’) which create this hair in highly collimated ‘combed’ configurations. We construct and analyze time-symmetric classical solutions of 2 + 1 Einstein-Hilbert gravity such as might be created by smeared versions of such operators. We focus on the AdS3 case, where this hair is characterized by the profile of the boundary stress tensor; the desired solutions are those where the boundary stress tensor at initial time t = 0 agrees precisely with its vacuum value outside an angular interval [-α ,α ]. At linear order in source strength the energy is independent of the combing parameter α, but nonlinearities cause the full energy to diverge as α \\to 0. In general, solutions with combed gravitational flux also suffer from what we call displacement from their naive location. For weak sources and large α one may set the displacement to zero by further increasing the energy, though for strong sources and small α we find no preferred notion of a zero-displacement solution. In the latter case we conclude that naively expected gravitational Wilson lines do not exist. In the zero-displacement case, taking the AdS scale ℓ to infinity gives finite-energy flux-directed solutions that may be called asymptotically flat.

  15. Safe sex

    MedlinePlus

    Safe sex means taking steps before and during sex that can prevent you from getting an infection, or from ... the skin around the genital area. Before having sex: Get to know your partner and discuss your ...

  16. A Genomic Duplication is Associated with Ectopic Eomesodermin Expression in the Embryonic Chicken Comb and Two Duplex-comb Phenotypes

    PubMed Central

    Dorshorst, Ben; Rubin, Carl-Johan; Ashwell, Chris; Gourichon, David; Tixier-Boichard, Michèle; Hallböök, Finn; Andersson, Leif

    2015-01-01

    Duplex-comb (D) is one of three major loci affecting comb morphology in the domestic chicken. Here we show that the two Duplex-comb alleles, V-shaped (D*V) and Buttercup (D*C), are both associated with a 20 Kb tandem duplication containing several conserved putative regulatory elements located 200 Kb upstream of the eomesodermin gene (EOMES). EOMES is a T-box transcription factor that is involved in mesoderm specification during gastrulation. In D*V and D*C chicken embryos we find that EOMES is ectopically expressed in the ectoderm of the comb-developing region as compared to wild-type embryos. The confinement of the ectopic expression of EOMES to the ectoderm is in stark contrast to the causal mechanisms underlying the two other major comb loci in the chicken (Rose-comb and Pea-comb) in which the transcription factors MNR2 and SOX5 are ectopically expressed strictly in the mesenchyme. Interestingly, the causal mutations of all three major comb loci in the chicken are now known to be composed of large-scale structural genomic variants that each result in ectopic expression of transcription factors. The Duplex-comb locus also illustrates the evolution of alleles in domestic animals, which means that alleles evolve by the accumulation of two or more consecutive mutations affecting the phenotype. We do not yet know whether the V-shaped or Buttercup allele correspond to the second mutation that occurred on the haplotype of the original duplication event. PMID:25789773

  17. A genomic duplication is associated with ectopic eomesodermin expression in the embryonic chicken comb and two duplex-comb phenotypes.

    PubMed

    Dorshorst, Ben; Harun-Or-Rashid, Mohammad; Bagherpoor, Alireza Jian; Rubin, Carl-Johan; Ashwell, Chris; Gourichon, David; Tixier-Boichard, Michèle; Hallböök, Finn; Andersson, Leif

    2015-03-01

    Duplex-comb (D) is one of three major loci affecting comb morphology in the domestic chicken. Here we show that the two Duplex-comb alleles, V-shaped (D*V) and Buttercup (D*C), are both associated with a 20 Kb tandem duplication containing several conserved putative regulatory elements located 200 Kb upstream of the eomesodermin gene (EOMES). EOMES is a T-box transcription factor that is involved in mesoderm specification during gastrulation. In D*V and D*C chicken embryos we find that EOMES is ectopically expressed in the ectoderm of the comb-developing region as compared to wild-type embryos. The confinement of the ectopic expression of EOMES to the ectoderm is in stark contrast to the causal mechanisms underlying the two other major comb loci in the chicken (Rose-comb and Pea-comb) in which the transcription factors MNR2 and SOX5 are ectopically expressed strictly in the mesenchyme. Interestingly, the causal mutations of all three major comb loci in the chicken are now known to be composed of large-scale structural genomic variants that each result in ectopic expression of transcription factors. The Duplex-comb locus also illustrates the evolution of alleles in domestic animals, which means that alleles evolve by the accumulation of two or more consecutive mutations affecting the phenotype. We do not yet know whether the V-shaped or Buttercup allele correspond to the second mutation that occurred on the haplotype of the original duplication event. PMID:25789773

  18. Optimal Sharpening of Compensated Comb Decimation Filters: Analysis and Design

    PubMed Central

    Troncoso Romero, David Ernesto

    2014-01-01

    Comb filters are a class of low-complexity filters especially useful for multistage decimation processes. However, the magnitude response of comb filters presents a droop in the passband region and low stopband attenuation, which is undesirable in many applications. In this work, it is shown that, for stringent magnitude specifications, sharpening compensated comb filters requires a lower-degree sharpening polynomial compared to sharpening comb filters without compensation, resulting in a solution with lower computational complexity. Using a simple three-addition compensator and an optimization-based derivation of sharpening polynomials, we introduce an effective low-complexity filtering scheme. Design examples are presented in order to show the performance improvement in terms of passband distortion and selectivity compared to other methods based on the traditional Kaiser-Hamming sharpening and the Chebyshev sharpening techniques recently introduced in the literature. PMID:24578674

  19. High density terahertz frequency comb produced by coherent synchrotron radiation

    PubMed Central

    Tammaro, S.; Pirali, O.; Roy, P.; Lampin, J.-F.; Ducournau, G.; Cuisset, A.; Hindle, F.; Mouret, G.

    2015-01-01

    Frequency combs have enabled significant progress in frequency metrology and high-resolution spectroscopy extending the achievable resolution while increasing the signal-to-noise ratio. In its coherent mode, synchrotron radiation is accepted to provide an intense terahertz continuum covering a wide spectral range from about 0.1 to 1 THz. Using a dedicated heterodyne receiver, we reveal the purely discrete nature of this emission. A phase relationship between the light pulses leads to a powerful frequency comb spanning over one decade in frequency. The comb has a mode spacing of 846 kHz, a linewidth of about 200 Hz, a fractional precision of about 2 × 10−10 and no frequency offset. The unprecedented potential of the comb for high-resolution spectroscopy is demonstrated by the accurate determination of pure rotation transitions of acetonitrile. PMID:26190043

  20. Propagators of random walks on comb lattices of arbitrary dimension

    NASA Astrophysics Data System (ADS)

    Illien, Pierre; Bénichou, Olivier

    2016-07-01

    We study diffusion on comb lattices of arbitrary dimension. Relying on the loopless structure of these lattices and using first-passage properties, we obtain exact and explicit formulae for the Laplace transforms of the propagators associated to nearest-neighbour random walks in both cases where either the first or the last point of the random walk is on the backbone of the lattice, and where the two extremities are arbitrarily chosen. As an application, we compute the mean-square displacement of a random walker on a comb of arbitrary dimension. We also propose an alternative and consistent approach of the problem using a master equation description, and obtain simple and generic expressions of the propagators. This method is more general and is extended to study the propagators of random walks on more complex comb-like structures. In particular, we study the case of a two-dimensional comb lattice with teeth of finite length.

  1. Measurement of microresonator frequency comb coherence by spectral interferometry.

    PubMed

    Webb, K E; Jang, J K; Anthony, J; Coen, S; Erkintalo, M; Murdoch, S G

    2016-01-15

    We experimentally investigate the spectral coherence of microresonator optical frequency combs. Specifically, we use a spectral interference method, typically used in the context of supercontinuum generation, to explore the variation of the magnitude of the complex degree of first-order coherence across the full comb bandwidth. We measure the coherence of two different frequency combs and observe wholly different coherence characteristics. In particular, we find that the observed dynamical regimes are similar to the stable and unstable modulation instability regimes reported in previous theoretical studies. Results from numerical simulations are found to be in good agreement with experimental observations. In addition to demonstrating a new technique to assess comb stability, our results provide strong experimental support for previous theoretical analyses. PMID:26766693

  2. Microstructural properties of {InAs}/{InAsxSb1 - x} superlattices and InAs xSb 1 - x ordered alloys grown by modulated molecular beam epitaxy

    NASA Astrophysics Data System (ADS)

    Zhang, Y.-H.; Lew, A.; Yu, E.; Chen, Y.

    1997-05-01

    Modulated molecular beam epitaxy (MMBE) has been demonstrated to be useful in controlling group-V alloys such as InAs xSb 1 - x and AlAs xSb 1 - x. Further studies of the MMBE grown InAs xSb 1 - x ordered alloys and {InAs}/{InAsxSb1 - x} superlattices by using cross-sectional scanning tunneling microscopy show well defined interfaces between InAs xSb 1 - x ordered alloys and InAs. Clear composition modulation is observed in the InAs xSb 1 - x ordered alloy layers. Transmission electron diffraction and microscopy, X-ray diffraction, and low temperature photoluminescence experiments show no obvious sign of CuPt orderings. These results suggest that MMBE provides a possible means to bypass the ordering problem of InAs xSb 1 - x random alloys.

  3. Kerr optical frequency combs: theory, applications and perspectives

    NASA Astrophysics Data System (ADS)

    Chembo, Yanne K.

    2016-06-01

    The optical frequency comb technology is one of the most important breakthrough in photonics in recent years. This concept has revolutionized the science of ultra-stable lightwave and microwave signal generation. These combs were originally generated using ultrafast mode-locked lasers, but in the past decade, a simple and elegant alternativewas proposed,which consisted in pumping an ultra-high-Q optical resonator with Kerr nonlinearity using a continuous-wave laser. When optimal conditions are met, the intracavity pump photons are redistributed via four-wave mixing to the neighboring cavity modes, thereby creating the so-called Kerr optical frequency comb. Beyond being energy-efficient, conceptually simple, and structurally robust, Kerr comb generators are very compact devices (millimetric down to micrometric size) which can be integrated on a chip. They are, therefore, considered as very promising candidates to replace femtosecond mode-locked lasers for the generation of broadband and coherent optical frequency combs in the spectral domain, or equivalently, narrow optical pulses in the temporal domain. These combs are, moreover, expected to provide breakthroughs in many technological areas, such as integrated photonics, metrology, optical telecommunications, and aerospace engineering. The purpose of this review article is to present a comprehensive survey of the topic of Kerr optical frequency combs.We provide an overview of the main theoretical and experimental results that have been obtained so far. We also highlight the potential of Kerr combs for current or prospective applications, and discuss as well some of the open challenges that are to be met at the fundamental and applied level.

  4. Stabilization of femtosecond laser frequency combs with subhertz residual linewidths.

    PubMed

    Bartels, A; Oates, C W; Hollberg, L; Diddams, S A

    2004-05-15

    We demonstrate that femtosecond laser frequency combs (FLFCs) can have a subhertz linewidth across their entire emission spectra when they are phase locked to a reference laser with a similarly narrow linewidth. Correspondingly, the coherence time of the comb components relative to the reference laser can be of the order of a few seconds. Thus we are able to detect high-contrast spectral interferograms at up to 10-s integration time between two FLFCs locked to a common optical reference. PMID:15181992

  5. Disorder and order in unfolded and disordered peptides and proteins: a view derived from tripeptide conformational analysis. II. Tripeptides with short side chains populating asx and β-type like turn conformations.

    PubMed

    Rybka, Karin; Toal, Siobhan E; Verbaro, Daniel J; Mathieu, Daniel; Schwalbe, Harald; Schweitzer-Stenner, Reinhard

    2013-06-01

    In the preceding paper, we found that ensembles of tripeptides with long or bulky chains can include up to 20% of various turns. Here, we determine the structural and thermodynamic characteristics of GxG peptides with short polar and/or ionizable central residues (D, N, C), whose conformational distributions exhibit higher than average percentage (>20%) of turn conformations. To probe the side-chain conformations of these peptides, we determined the (3)J(H(α),H(β)) coupling constants and derived the population of three rotamers with χ1 -angles of -60°, 180° and 60°, which were correlated with residue propensities by DFT-calculations. For protonated GDG, the rotamer distribution provides additional evidence for asx-turns. A comparison of vibrational spectra and NMR coupling constants of protonated GDG, ionized GDG, and the protonated aspartic acid dipeptide revealed that side chain protonation increases the pPII content at the expense of turn populations. The charged terminal groups, however, have negligible influence on the conformational properties of the central residue. Like protonated GDG, cationic GCG samples asx-turns to a significant extent. The temperature dependence of the UVCD spectra and (3)J(H(N)H(α)) constants suggest that the turn populations of GDG and GNG are practically temperature-independent, indicating enthalpic and entropic stabilization. The temperature-independent J-coupling and UVCD spectra of GNG require a three-state model. Our results indicate that short side chains with hydrogen bonding capability in GxG segments of proteins may serve as hinge regions for establishing compact structures of unfolded proteins and peptides. PMID:23229867

  6. Dynamics of the modulational instability in microresonator frequency combs

    NASA Astrophysics Data System (ADS)

    Hansson, T.; Modotto, D.; Wabnitz, S.

    2013-08-01

    A study is made of frequency-comb generation described by the driven and damped nonlinear Schrödinger equation on a finite interval. It is shown that frequency-comb generation can be interpreted as a modulational instability of the continuous-wave pump mode, and a linear stability analysis, taking into account the cavity boundary conditions, is performed. Further, a truncated three-wave model is derived, which allows one to gain additional insight into the dynamical behavior of the comb generation. This formalism describes the pump mode and the most unstable sideband and is found to connect the coupled mode theory with the conventional theory of modulational instability. An in-depth analysis is done of the nonlinear three-wave model. It is demonstrated that stable frequency-comb states can be interpreted as attractive fixed points of a dynamical system. The possibility of soft and hard excitation states in both the normal and the anomalous dispersion regime is discussed. Investigations are made of bistable comb states and the dependence of the final state on the way the comb has been generated. The analytical predictions are verified by means of direct comparison with numerical simulations of the full equation and the agreement is discussed.

  7. Adaptive real-time dual-comb spectroscopy.

    PubMed

    Ideguchi, Takuro; Poisson, Antonin; Guelachvili, Guy; Picqué, Nathalie; Hänsch, Theodor W

    2014-01-01

    The spectrum of a laser frequency comb consists of several hundred thousand equally spaced lines over a broad spectral bandwidth. Such frequency combs have revolutionized optical frequency metrology and they now hold much promise for significant advances in a growing number of applications including molecular spectroscopy. Despite an intriguing potential for the measurement of molecular spectra spanning tens of nanometres within tens of microseconds at Doppler-limited resolution, the development of dual-comb spectroscopy is hindered by the demanding stability requirements of the laser combs. Here we overcome this difficulty and experimentally demonstrate a concept of real-time dual-comb spectroscopy, which compensates for laser instabilities by electronic signal processing. It only uses free-running mode-locked lasers without any phase-lock electronics. We record spectra spanning the full bandwidth of near-infrared fibre lasers with Doppler-limited line profiles highly suitable for measurements of concentrations or line intensities. Our new technique of adaptive dual-comb spectroscopy offers a powerful transdisciplinary instrument for analytical sciences. PMID:24572636

  8. Adaptive real-time dual-comb spectroscopy

    PubMed Central

    Ideguchi, Takuro; Poisson, Antonin; Guelachvili, Guy; Picqué, Nathalie; Hänsch, Theodor W.

    2014-01-01

    The spectrum of a laser frequency comb consists of several hundred thousand equally spaced lines over a broad spectral bandwidth. Such frequency combs have revolutionized optical frequency metrology and they now hold much promise for significant advances in a growing number of applications including molecular spectroscopy. Despite an intriguing potential for the measurement of molecular spectra spanning tens of nanometres within tens of microseconds at Doppler-limited resolution, the development of dual-comb spectroscopy is hindered by the demanding stability requirements of the laser combs. Here we overcome this difficulty and experimentally demonstrate a concept of real-time dual-comb spectroscopy, which compensates for laser instabilities by electronic signal processing. It only uses free-running mode-locked lasers without any phase-lock electronics. We record spectra spanning the full bandwidth of near-infrared fibre lasers with Doppler-limited line profiles highly suitable for measurements of concentrations or line intensities. Our new technique of adaptive dual-comb spectroscopy offers a powerful transdisciplinary instrument for analytical sciences. PMID:24572636

  9. Adaptive real-time dual-comb spectroscopy

    NASA Astrophysics Data System (ADS)

    Ideguchi, Takuro; Poisson, Antonin; Guelachvili, Guy; Picqué, Nathalie; Hänsch, Theodor W.

    2014-02-01

    The spectrum of a laser frequency comb consists of several hundred thousand equally spaced lines over a broad spectral bandwidth. Such frequency combs have revolutionized optical frequency metrology and they now hold much promise for significant advances in a growing number of applications including molecular spectroscopy. Despite an intriguing potential for the measurement of molecular spectra spanning tens of nanometres within tens of microseconds at Doppler-limited resolution, the development of dual-comb spectroscopy is hindered by the demanding stability requirements of the laser combs. Here we overcome this difficulty and experimentally demonstrate a concept of real-time dual-comb spectroscopy, which compensates for laser instabilities by electronic signal processing. It only uses free-running mode-locked lasers without any phase-lock electronics. We record spectra spanning the full bandwidth of near-infrared fibre lasers with Doppler-limited line profiles highly suitable for measurements of concentrations or line intensities. Our new technique of adaptive dual-comb spectroscopy offers a powerful transdisciplinary instrument for analytical sciences.

  10. Parentage and relatedness in polyandrous comb-crested jacanas using ISSRs

    USGS Publications Warehouse

    Haig, Susan M.; Mace, Terrence R.; Mullins, Thomas D.

    2003-01-01

    In this article we present the first analysis of parentage and relatedness in a natural vertebrate population, using Intersimple Sequence Repeat (ISSR) markers. Thus, 28 ISSR markers were used in a study of a sex-role reversed, simultaneously polyandrous shorebird from northeastern Australia, the comb-crested jacana (Irediparra gallinacea). Assessment of parentage was based on comparison of field observations, novel bands, individual-specific bands found in 7/9 males and 4/6 females, and a 99% CI exclusion criteria. Integrating results from these approaches resulted in confirmation of paternity in all 36 chicks. In only one case (2.8% of chicks) was a co-mate assigned paternity. Thus, comb-crested jacanas appear to be genetically monogamous. These results showed resemblance to sequentially polyandrous birds but differed from the simultaneously polyandrous wattled jacana ( Jacana jacana; Emlen et al. 1998). A significant relationship between relatedness and ISSR similarity resulted in recognition that 14/15 adults sampled may be related to at least one other adult by 0.25 or more. Lack of dispersal may be explained by physical limitations and adequate regional habitat. ISSRs proved to be simple and helpful in resolving these issues.

  11. Treatment of head lice (Pediculus humanus capitis) infestation: is regular combing alone with a special detection comb effective at all levels?

    PubMed

    Kurt, Özgür; Balcıoğlu, I Cüneyt; Limoncu, M Emin; Girginkardeşler, Nogay; Arserim, Süha K; Görgün, Serhan; Oyur, Tuba; Karakuş, Mehmet; Düzyol, Didem; Gökmen, Aysegül Aksoy; Kitapçıoğlu, Gül; Özbel, Yusuf

    2015-04-01

    Head lice infestation (HLI) caused by Pediculus humanus capitis has been a public health problem worldwide. Specially designed combs are used to identify head lice, while anti-lice products are applied on the scalp for treatment. In the present study, we aimed to test whether combing only by precision detection comb (PDC) or metal pin comb (MPC) could be effective alternatives to the use of anti-lice products in children. A total of 560 children from two rural schools in Turkey were screened. In the PDC trial, children were combed every second day for 14 days, while in the MPC trial, combing was performed once in every four days for 15 days. Children were divided into two groups (dry combing and wet combing) for both trials and results were compared. The results showed no significant differences between dry and wet combing strategies for both combs for the removal of head lice (p > 0.05). The number of adult head lice declined significantly on each subsequent combing day in both approaches, except on day 15 in the MPC trial. In the end, no louse was found in 54.1 and 48.9% of children in the PDC and MPC trials, respectively. Since family members of infested children were not available, they were not checked for HLI. Four times combing within 2 weeks with MPC combs was found effective for both treatment of low HLI and prevention of heavy HLI. In conclusion, regular combing by special combs decreases HLI level in children and is safely applicable as long-term treatment. PMID:25604670

  12. Self-Injection Locking and Phase-Locked States in Microresonator-Based Optical Frequency Combs

    NASA Astrophysics Data System (ADS)

    Del'Haye, Pascal; Beha, Katja; Papp, Scott B.; Diddams, Scott A.

    2014-01-01

    Microresonator-based optical frequency combs have been a topic of extensive research during the last few years. Several theoretical models for the comb generation have been proposed; however, they do not comprehensively address experimental results that show a variety of independent comb generation mechanisms. Here, we present frequency-domain experiments that illuminate the transition of microcombs into phase-locked states, which show characteristics of injection locking between ensembles of comb modes. In addition, we demonstrate the existence of equidistant optical frequency combs that are phase stable but have nondeterministic phase relationships between individual comb modes.

  13. Self-injection locking and phase-locked states in microresonator-based optical frequency combs.

    PubMed

    Del'Haye, Pascal; Beha, Katja; Papp, Scott B; Diddams, Scott A

    2014-01-31

    Microresonator-based optical frequency combs have been a topic of extensive research during the last few years. Several theoretical models for the comb generation have been proposed; however, they do not comprehensively address experimental results that show a variety of independent comb generation mechanisms. Here, we present frequency-domain experiments that illuminate the transition of microcombs into phase-locked states, which show characteristics of injection locking between ensembles of comb modes. In addition, we demonstrate the existence of equidistant optical frequency combs that are phase stable but have nondeterministic phase relationships between individual comb modes. PMID:24580454

  14. Versatile and Sensitive Dual Comb Fourier Transform Spectroscopy

    NASA Astrophysics Data System (ADS)

    Jacquey, M.; Jacquet, P.; Mandon, J.; Thon, R.; Guelachvili, G.; Hänsch, T. W.; Picqué, N.

    2010-06-01

    Fourier transform spectroscopy based on time-domain interferences between two slightly detuned frequency comb sources holds much promise for the real-time diagnostic of gaseous, liquid or solid-state samples. In one very recent example, cavity-enhanced absorption spectroscopy with two infrared frequency combs has demonstrated a dramatically enhanced sensitivity, compared to conventional Fourier spectroscopy, with intriguing implications for instantaneous trace gas analysis. It however remains challenging to match continuously the comb and cavity modes across a broad spectral bandwidth during the time of a measurement. An obvious alternative for reaching a long interaction path is a conventional multipass cell. Additionally, differential detection schemes may be devised to increase the dynamic range of the interferometric measurements, thus providing enhanced signal to noise ratio. Experimental demonstrations will be given in the 1.5 μm region with a dual comb set-up based on two Er-doped fiber femtosecond lasers. The versatility and performances of these solutions will be compared to the cavity-enhanced dual comb technique and other state-of-the-art alternatives. P. Jacquet, J. Mandon, B. Bernhardt, R. Holzwarth, G. Guelachvili, T. W. Hänsch, N. Picqué, Frequency Comb Fourier Transform Spectroscopy with kHz Optical Resolution, The Optical Society of America, Washington, DC 2009, paper FMB2 (2009). B. Bernhardt, A. Ozawa, P. Jacquet, M. Jacquey, Y. Kobayashi, T. Udem, R. Holzwarth, G. Guelachvili, T.W. Hänsch, N. Picqué, Cavity-enhanced dual-comb spectroscopy, Nature Photonics 4, 55-57 (2010),

  15. Nonlinear Dual-Comb Spectroscopy with Two-Photon Excitation

    NASA Astrophysics Data System (ADS)

    Meek, S. A.; Hipke, A.; Hansch, T. W.; Picque, N.

    2013-06-01

    Dual frequency comb spectroscopy has proven to be a powerful method for acquiring broadband, high resolution spectra with measurement times that are much shorter than in traditional moving-mirror Fourier transform spectroscopy. Because the measurements are carried out with femtosecond lasers, this technique has great potential for decreasing the measurement times and improving the signal-to-noise ratio of nonlinear spectroscopic measurements, such as two-photon excitation or Raman processes. In the case of two-photon excitation, an entire spectrum can be obtained at a given signal level using dual-comb spectroscopy in the same time that a measurement of a single transition frequency would be obtained with a continuous laser of the same average power. In this presentation, I will show the latest results in extending the dual-comb technique to two-photon excitation spectroscopy, with measurements on gas-phase rubidium and liquid-phase dye samples. In our realization of dual-comb spectroscopy, two frequency combs with slightly different repetition rates are combined on a beam splitter and directed into a sample, and we measure the intensity of the resulting fluorescence as a function of time. Because of the different repetition rates, the time delay between a pulse from the first comb and the next pulse from the second comb changes linearly with time, simulating the action of the moving mirror in a traditional Michelson interferometer. The Fourier transform of the measured time-domain interferogram produces a radio-frequency spectrum that can be directly converted to a broadband optical spectrum through a linear scaling of the frequency. To achieve the highest possible resolution, it is necessary to compensate the residual relative fluctuations of the repetition rate and the carrier-envelope offset frequency of the frequency combs. Measuring RF beatnotes of each comb with two CW lasers provides two error signals that can be used to correct the recorded interferograms

  16. Broadband Comb-Resolved Cavity Enhanced Spectrometer with Graphene Modulator

    NASA Astrophysics Data System (ADS)

    Lee, Kevin; Mohr, Christian; Jiang, Jie; Fermann, Martin; Lee, Chien-Chung; Schibli, Thomas R.; Kowzan, Grzegorz; Maslowski, Piotr

    2015-06-01

    Optical cavities enhance sensitivity in absorption spectroscopy. While this is commonly done with single wavelengths, broad bandwidths can be coupled into the cavity using frequency combs. The combination of cavity enhancement and broad bandwidth allows simultaneous measurement of tens of transitions with high signal-to-noise for even weak near-infrared transitions. This removes the need for time-consuming sequencing acquisition or long-term averaging, so any systematic errors from long-term drifts of the experimental setup or slow changes of sample composition are minimized. Resolving comb lines provides a high accuracy, absolute frequency axis. This is of great importance for gas metrology and data acquisition for future molecular lines databases, and can be applied to simultaneous trace-gas detection of gas mixtures. Coupling of a frequency comb into a cavity can be complex, so we introduce and demonstrate a simplification. The Pound-Drever-Hall method for locking a cavity and a frequency comb together requires a phase modulation of the laser output. We use the graphene modulator that is already in the Tm fiber laser cavity for controlling the carrier envelope offset of the frequency comb, rather than adding a lossy external modulator. The graphene modulator can operate at frequencies of over 1~ MHz, which is sufficient for controlling the laser cavity length actuator which operates below 100~kHz. We match the laser cavity length to fast variations of the enhancement cavity length. Slow variations are stabilized by comparison of the pulse repetition rate to a GPS reference. The carrier envelope offset is locked to a constant value chosen to optimize the transmitted spectrum. The transmitted pulse train is a stable frequency comb suitable for long measurements, including the acquisition of comb-resolved Fourier transform spectra with a minimum absorption coefficient of about 2×10-7 wn. For our 38 cm long enhancement cavity, the comb spacing is 394~MHz. With our

  17. Laser frequency comb techniques for precise astronomical spectroscopy

    NASA Astrophysics Data System (ADS)

    Murphy, Michael T.; Locke, Clayton R.; Light, Philip S.; Luiten, Andre N.; Lawrence, Jon S.

    2012-05-01

    Precise astronomical spectroscopic analyses routinely assume that individual pixels in charge-coupled devices (CCDs) have uniform sensitivity to photons. Intra-pixel sensitivity (IPS) variations may already cause small systematic errors in, for example, studies of extra-solar planets via stellar radial velocities and cosmological variability in fundamental constants via quasar spectroscopy, but future experiments requiring velocity precisions approaching ˜1 cm s-1 will be more strongly affected. Laser frequency combs have been shown to provide highly precise wavelength calibration for astronomical spectrographs, but here we show that they can also be used to measure IPS variations in astronomical CCDs in situ. We successfully tested a laser frequency comb system on the Ultra-High-Resolution Facility spectrograph at the Anglo-Australian Telescope. By modelling the two-dimensional comb signal recorded in a single CCD exposure, we find that the average IPS deviates by <8 per cent if it is assumed to vary symmetrically about the pixel centre. We also demonstrate that a series of comb exposures with absolutely known offsets between them can yield tighter constraints on symmetric IPS variations from ˜100 pixels. We discuss measurement of asymmetric IPS variations and absolute wavelength calibration of astronomical spectrographs and CCDs using frequency combs.

  18. Structure and effective interactions of comb polymer nanocomposite melts

    NASA Astrophysics Data System (ADS)

    Xu, Qinzhi; Xu, Mengjin; Feng, Yancong; Chen, Lan

    2014-11-01

    In this work, the structure and effective interactions of branched comb polymer nanocomposite (PNC) melts are investigated by using the polymer reference interaction site model (PRISM) integral equation theory. It is observed that the nanoparticle contact (bridging) aggregation is formed when the nanoparticle-monomer attraction strength is relatively weak (large) in comb PNCs. The organization states of aggregation for the moderate nanoparticle-monomer attraction strength can be well suppressed by the comb polymer architecture, while the bridging structure for relatively large attraction is obviously promoted. With the increase of the particle volume fraction, the organization states of bridging-type structure become stronger and tighter; however, this effect is weaker than that of the nanoparticle-monomer attraction strength. When the particle volume fraction and moderate nanoparticle-monomer attraction strength are fixed, the effects of degree of polymerization, side chain number, side chain length, and nanoparticle-monomer size ratio on the organization states of PNC melts are not prominent and the nanoparticles can well disperse in comb polymer. All the observations indicate that the present PRISM theory can give a detailed description of the comb PNC melts and assist in future design control of new nanomaterials.

  19. Phrenology, heredity and progress in George Combe's Constitution of Man.

    PubMed

    Jenkins, Bill

    2015-09-01

    The Constitution of Man by George Combe (1828) was probably the most influential phrenological work of the nineteenth century. It not only offered an exposition of the phrenological theory of the mind, but also presented Combe's vision of universal human progress through the inheritance of acquired mental attributes. In the decades before the publication of Darwin's Origin of Species, the Constitution was probably the single most important vehicle for the dissemination of naturalistic progressivism in the English-speaking world. Although there is a significant literature on the social and cultural context of phrenology, the role of heredity in Combe's thought has been less thoroughly explored, although both John van Wyhe and Victor L. Hilts have linked Combe's views on heredity with the transformist theories of Jean-Baptiste Lamarck. In this paper I examine the origin, nature and significance of his ideas and argue that Combe's hereditarianism was not directly related to Lamarckian transformism but formed part of a wider discourse on heredity in the early nineteenth century. PMID:25998794

  20. Brood comb as a humidity buffer in honeybee nests

    NASA Astrophysics Data System (ADS)

    Ellis, Michael B.; Nicolson, Sue W.; Crewe, Robin M.; Dietemann, Vincent

    2010-04-01

    Adverse environmental conditions can be evaded, tolerated or modified in order for an organism to survive. During their development, some insect larvae spin cocoons which, in addition to protecting their occupants against predators, modify microclimatic conditions, thus facilitating thermoregulation or reducing evaporative water loss. Silk cocoons are spun by honeybee ( Apis mellifera) larvae and subsequently incorporated into the cell walls of the wax combs in which they develop. The accumulation of this hygroscopic silk in the thousands of cells used for brood rearing may significantly affect nest homeostasis by buffering humidity fluctuations. This study investigates the extent to which the comb may influence homeostasis by quantifying the hygroscopic capacity of the cocoons spun by honeybee larvae. When comb containing cocoons was placed at high humidity, it absorbed 11% of its own mass in water within 4 days. Newly drawn comb composed of hydrophobic wax and devoid of cocoons absorbed only 3% of its own mass. Therefore, the accumulation of cocoons in the comb may increase brood survivorship by maintaining a high and stable humidity in the cells.

  1. Adsorption of comb copolymers on weakly attractive solid surfaces.

    PubMed

    Striolo, A; Jayaraman, A; Genzer, J; Hall, C K

    2005-08-01

    In this work continuum and lattice Monte Carlo simulation methods are used to study the adsorption of linear and comb polymers on flat surfaces. Selected polymer segments, located at the tips of the side chains in comb polymers or equally spaced along the linear polymers, are attracted to each other and to the surface via square-well potentials. The rest of the polymer segments are modeled as tangent hard spheres in the continuum model and as self-avoiding random walks in the lattice model. Results are presented in terms of segment-density profiles, distribution functions, and radii of gyration of the adsorbed polymers. At infinite dilution the presence of short side chains promotes the adsorption of polymers favoring both a decrease in the depletion-layer thickness and a spreading of the polymer molecule on the surface. The presence of long side chains favors the adsorption of polymers on the surface, but does not permit the spreading of the polymers. At finite concentration linear polymers and comb polymers with long side chains readily adsorb on the solid surface, while comb polymers with short side chains are unlikely to adsorb. The simple models of comb copolymers with short side chains used here show properties similar to those of associating polymers and of globular proteins in aqueous solutions, and can be used as a first approximation to investigate the mechanism of adsorption of proteins onto hydrophobic surfaces. PMID:16122338

  2. Sex Films

    ERIC Educational Resources Information Center

    Francoeur, Robert T.

    1977-01-01

    Describes a new concept in sex education, the sexual attitudes reassessment workshop. This workshop satiates, saturates, desensitizes, and demythologizes sex. It bypasses the intellect and forces people to deal with feeling and attitudes. (Author/AM)

  3. Astro-comb calibration of an Echelle Spectrograph

    NASA Astrophysics Data System (ADS)

    Li, C.-H.; Phillips, D. F.; Glenday, A. G.; Benedick, A. J.; Chang, G.; Chen, L.-J.; Cramer, C.; Furesz, G.; Kärtner, F. X.; Sasselov, D.; Szentgyorgyi, A.; Walsworth, R. L.

    2010-07-01

    We describe recent work calibrating a cross-dispersed spectrograph with an "astro-comb" i.e., a high repetition rate, octave spanning femtosecond laser frequency comb; and a filter cavity suppressing laser modes to match the resolution of the spectrograph. Our astro-comb provides ~1500 evenly spaced (~0.6 A) calibration lines of roughly 100 nW per line between 7800 and 8800 Angstroms. The calibration lines of the laser are stabilized to atomic clocks which can be referenced to GPS providing intrinsic stability of the source laser below 1 cm/s in stellar radial velocity sensitivity, as well as long term stability and reproducibility over years. We present calibration of the TRES spectrograph at the 1.5 m telescope at the Fred L Whipple Observatory below 1 m/s radial velocity sensitivity in six orders from 7800-8800 A.

  4. Quantum cascade laser combs: effects of modulation and dispersion.

    PubMed

    Villares, Gustavo; Faist, Jérôme

    2015-01-26

    Frequency comb formation in quantum cascade lasers is studied theoretically using a Maxwell-Bloch formalism based on a modal decomposition, where dispersion is considered. In the mid-infrared, comb formation persists in the presence of weak cavity dispersion (500 fs2 mm-1) but disappears when much larger values are used (30'000 fs2 mm-1). Active modulation at the round-trip frequency is found to induce mode-locking in THz devices, where the upper state lifetime is in the tens of picoseconds. Our results show that mode-locking based on four-wave mixing in broadband gain, low dispersion cavities is the most promising way of achieving broadband quantum cascade laser frequency combs. PMID:25835922

  5. Nonlinear amplification of side-modes in frequency combs.

    PubMed

    Probst, R A; Steinmetz, T; Wilken, T; Hundertmark, H; Stark, S P; Wong, G K L; Russell, P St J; Hänsch, T W; Holzwarth, R; Udem, Th

    2013-05-20

    We investigate how suppressed modes in frequency combs are modified upon frequency doubling and self-phase modulation. We find, both experimentally and by using a simplified model, that these side-modes are amplified relative to the principal comb modes. Whereas frequency doubling increases their relative strength by 6 dB, the growth due to self-phase modulation can be much stronger and generally increases with nonlinear propagation length. Upper limits for this effect are derived in this work. This behavior has implications for high-precision calibration of spectrographs with frequency combs used for example in astronomy. For this application, Fabry-Pérot filter cavities are used to increase the mode spacing to exceed the resolution of the spectrograph. Frequency conversion and/or spectral broadening after non-perfect filtering reamplify the suppressed modes, which can lead to calibration errors. PMID:23736390

  6. Methods and apparatus for broadband frequency comb stabilization

    SciTech Connect

    Cox, Jonathan A; Kaertner, Franz X

    2015-03-17

    Feedback loops can be used to shift and stabilize the carrier-envelope phase of a frequency comb from a mode-locked fibers laser or other optical source. Compared to other frequency shifting and stabilization techniques, feedback-based techniques provide a wideband closed-loop servo bandwidth without optical filtering, beam pointing errors, or group velocity dispersion. It also enables phase locking to a stable reference, such as a Ti:Sapphire laser, continuous-wave microwave or optical source, or self-referencing interferometer, e.g., to within 200 mrad rms from DC to 5 MHz. In addition, stabilized frequency combs can be coherently combined with other stable signals, including other stabilized frequency combs, to synthesize optical pulse trains with pulse durations of as little as a single optical cycle. Such a coherent combination can be achieved via orthogonal control, using balanced optical cross-correlation for timing stabilization and balanced homodyne detection for phase stabilization.

  7. Green astro-comb for HARPS-N

    NASA Astrophysics Data System (ADS)

    Langellier, Nicholas; Li, Chih-Hao; Glenday, Alexander G.; Chang, Guoqing; Chen, Hung-Wen; Lim, Jinkang; Furesz, Gabor; Kärtner, Franz; Phillips, David F.; Sasselov, Dimitar; Szentgyorgyi, Andrew; Walsworth, Ronald

    2014-08-01

    We report the design, installation and testing of a broadband green astro-comb on the HARPS-N spectrograph at the TNG telescope. The astro-comb consists of over 7000 narrow lines (<10-6 nm width) spaced by 16 GHz (0.02 nm at 550 nm) with wavelengths stabilized to the Global Positioning System (GPS) and with flat power from 500 to 620 nm. The narrow lines are used to calibrate the spectrograph and measure its line profile. The short term sensitivity of HARPS-N is measured to be less than 2 cm/s and the long-term drift of the spectrograph is approximately 10 cm/s/day. The astrocomb has been partially automated with future work planned to turn the astro-comb into a fully automated, push button instrument.

  8. Honeybee combs: construction through a liquid equilibrium process?

    NASA Astrophysics Data System (ADS)

    Pirk, C. W. W.; Hepburn, H. R.; Radloff, S. E.; Tautz, J.

    Geometrical investigations of honeycombs and speculations on how honeybees measure and construct the hexagons and rhombi of their cells are centuries old. Here we show that honeybees neither have to measure nor construct the highly regular structures of a honeycomb, and that the observed pattern of combs can be parsimoniously explained by wax flowing in liquid equilibrium. The structure of the combs of honeybees results from wax as a thermoplastic building medium, which softens and hardens as a result of increasing and decreasing temperatures. It flows among an array of transient, close-packed cylinders which are actually the self-heated honeybees themselves. The three apparent rhomboids forming the base of each cell do not exist but arise as optical artefacts from looking through semi-transparent combs.

  9. Characterization of a partially-stabilized frequency comb

    NASA Astrophysics Data System (ADS)

    Gold Dahl, M. E.; Erikson, Alex; Woodbury, Daniel; Bergeson, Scott

    2015-05-01

    We present measurements of well-known frequency intervals in Cs, Rb, and Ca. These measurements are used to determine the accuracy of a partially-stabilized ti:sapphire frequency comb. One mode of our frequency comb is offset-locked to a Rb-stabilized diode laser. The comb's repetition rate is counted but not locked. A second laser is used to probe well-known atomic transitions in Cs, Rb, and Ca. We describe our offset locking and scanning techniques and demonstrate a frequency precision of 10 kHz in a 30 second measurement time. The accuracy of our laser frequency interval measurements is approximately 40 kHz. However, cell-based frequency references can be off by several hundred kHz. Research supported by the National Science Foundation (Grant No. PHY-0969856) and the Air Force (Grant No. FA9950-12-1-0308).

  10. Direct Measurement of the XUV Frequency Comb Coherence

    NASA Astrophysics Data System (ADS)

    Benko, Craig; Allison, Thomas; Cingoz, Arman; Yost, Dylan; Ye, Jun

    2013-05-01

    We present the first demonstration of XUV radiation with phase coherence capable of reaching sub-kHz resolution. The XUV comb is produced by frequency up conversion of a near-infrared frequency comb by intra-cavity high harmonic generation (HHG). Using an 80 W Yb:fiber fs frequency comb, we simultaneously pump two femtosecond enhancement cavities to reach intensities suitable for HHG. The harmonics are out-coupled from the cavities using sapphire plates placed at Brewster angle for the pump laser. We developed an interferometer capable of operating in the XUV and measured a heterodyne beat between the two sources at different harmonics. Despite being insensitive to common-mode pump laser noise, the heterodyne beats will reveal any noise added by the intra-cavity HHG process. This will allow us to probe the fundamental limit on the coherence properties of HHG. We acknowledge support for this work from NIST, AFOSR, and NSF.

  11. Software reconfigurable highly flexible gain switched optical frequency comb source.

    PubMed

    Pascual, M Deseada Gutierrez; Zhou, Rui; Smyth, Frank; Anandarajah, Prince M; Barry, Liam P

    2015-09-01

    The authors present the performance and noise properties of a software reconfigurable, FSR and wavelength tunable gain switched optical frequency comb source. This source, based on the external injection of a temperature tuned Fabry-Pérot laser diode, offers quasi-continuous wavelength tunability over the C-band (30nm) and FSR tunability ranging from 6 to 14GHz. The results achieved demonstrate the excellent spectral quality of the comb tones (RIN ~-130dB/Hz and low phase noise of 300kHz) and its outstanding stability (with fluctuations of the individual comb tones of less than 0.5dB in power and 5pm in wavelength, characterized over 24hours) highlighting its suitability for employment in next generation flexible optical transmission networks. PMID:26368425

  12. Brillouin filtering of optical combs for narrow linewidth frequency synthesis

    NASA Astrophysics Data System (ADS)

    Galindo-Santos, Juan; Velasco, Aitor V.; Carrasco-Sanz, Ana; Corredera, Pedro

    2016-05-01

    We report a tunable monochromatic source generation scheme, based on Brillouin filtering of a self-referenced optical frequency comb. The system benefits from the high stability and mode linewidth of the frequency comb, significantly improving the performance of the original laser source used as Brillouin pump. A synthesized frequency with stability under 4×10-11 and a linewidth under 75 kHz was experimentally demonstrated for two separate pump lasers in the C-band. The proposed monochromatic source can be tuned with high precision in a very broad band by combining a coarse control with the pumping source and a fine control with the optical frequency comb references. In our experimental setup, coarse and fine tuning resolutions were 4 MHz and 20 Hz, respectively. Influence of Brillouin pump fluctuations in the synthesized signal stability were also analyzed for observation times up to 104 s.

  13. Spatiotemporal dynamics of Kerr-Raman optical frequency combs

    NASA Astrophysics Data System (ADS)

    Chembo, Yanne K.; Grudinin, Ivan S.; Yu, Nan

    2015-10-01

    Optical frequency combs generated with ultrahigh-Q whispering-gallery-mode resonators are expected to provide a compact, versatile, and energy-efficient source for the generation of coherent lightwave and microwave signals. So far, Kerr and Raman nonlinearities in these resonators have predominantly been investigated separately, even though both effects originate from the same third-order susceptibility. We present a spatiotemporal formalism for the theoretical understanding of these Kerr-Raman combs, which allows us to describe the complex interplay between both nonlinearities and all-order dispersion. These theoretical findings are successfully compared with experiments performed with ultrahigh-Q calcium and magnesium fluoride resonators.

  14. The generation of Continuous-Variable Entanglement Frequency Comb

    PubMed Central

    Yu, Youbin; Cheng, Xiaomin; Wang, Huaijun; Shi, Zhongtao; Zhao, Junwei; Ji, Fengmin; Yin, Zhi; Wang, Yajuan

    2015-01-01

    Continuous-variable (CV) entanglement frequency comb can be produced by enhanced Raman scattering in an above-threshold optical oscillator cavity in which a hexagonally-poled LiTaO3 crystal resides as a Raman gain medium. The Stokes and anti-Stokes Raman signals are enhanced by a coupled quasi-phase-matching optical parametric process and the entanglement natures among these Raman signals and pump are demonstrated by applying a sufficient inseparability criterion for CV entanglement. Such entanglement frequency comb source with different frequencies and continuously tunable frequency interval may be very significant for the applications in quantum communication and networks. PMID:25600617

  15. Monolithic device for modelocking and stabilization of frequency combs.

    PubMed

    Lee, C-C; Hayashi, Y; Silverman, K L; Feldman, A; Harvey, T; Mirin, R P; Schibli, T R

    2015-12-28

    We demonstrate a device that integrates a III-V semiconductor saturable absorber mirror with a graphene electro-optic modulator, which provides a monolithic solution to modelocking and noise suppression in a frequency comb. The device offers a pure loss modulation bandwidth exceeding 5 MHz and only requires a low voltage driver. This hybrid device provides not only compactness and simplicity in laser cavity design, but also small insertion loss, compared to the previous metallic-mirror-based modulators. We believe this work paves the way to portable and fieldable phase-coherent frequency combs. PMID:26831973

  16. The generation of continuous-variable entanglement frequency comb.

    PubMed

    Yu, Youbin; Cheng, Xiaomin; Wang, Huaijun; Shi, Zhongtao; Zhao, Junwei; Ji, Fengmin; Yin, Zhi; Wang, Yajuan

    2015-01-01

    Continuous-variable (CV) entanglement frequency comb can be produced by enhanced Raman scattering in an above-threshold optical oscillator cavity in which a hexagonally-poled LiTaO3 crystal resides as a Raman gain medium. The Stokes and anti-Stokes Raman signals are enhanced by a coupled quasi-phase-matching optical parametric process and the entanglement natures among these Raman signals and pump are demonstrated by applying a sufficient inseparability criterion for CV entanglement. Such entanglement frequency comb source with different frequencies and continuously tunable frequency interval may be very significant for the applications in quantum communication and networks. PMID:25600617

  17. 80 W, 120 fs Yb-fiber frequency comb.

    PubMed

    Ruehl, Axel; Marcinkevicius, Andrius; Fermann, Martin E; Hartl, Ingmar

    2010-09-15

    We report on a high-power fiber frequency comb exhibiting linear chirped-pulse amplification up to 80 W and generating 120 fs pulses. By proper matching of the group delay between the fiber stretcher and compressor, a compression ratio of 3100 could be achieved. Carrier envelope offset self-referencing and long-term phase locking to an rf reference is demonstrated, exemplifying the suitability of this system for generating vacuum and extreme-UV frequency combs via enhancement in passive cavities and high harmonic generation. PMID:20847763

  18. Routes to spatiotemporal chaos in Kerr optical frequency combs

    SciTech Connect

    Coillet, Aurélien; Chembo, Yanne K.

    2014-03-15

    We investigate the various routes to spatiotemporal chaos in Kerr optical frequency combs, obtained through pumping an ultra-high Q-factor whispering-gallery mode resonator with a continuous-wave laser. The Lugiato–Lefever model is used to build bifurcation diagrams with regards to the parameters that are externally controllable, namely, the frequency and the power of the pumping laser. We show that the spatiotemporal chaos emerging from Turing patterns and solitons display distinctive dynamical features. Experimental spectra of chaotic Kerr combs are also presented for both cases, in excellent agreement with theoretical spectra.

  19. Coherent combs in ionization by intense and short laser pulses

    NASA Astrophysics Data System (ADS)

    Krajewska, K.; Kamiński, J. Z.

    2016-03-01

    Photoionization of positive ions by a train of intense, short laser pulses is investigated within the relativistic strong field approximation, using the velocity gauge. The formation of broad peak structures in the high-energy domain of photoelectrons is observed and interpreted. The emergence of coherent photoelectron energy combs within these structures is demonstrated, and it is interpreted as the consequence of the Fraunhofer-type interference/diffraction of probability amplitudes of ionization from individual pulses comprising the train. Extensions to the coherent angular combs are also studied, and effects related to the radiation pressure are presented.

  20. The generation of Continuous-Variable Entanglement Frequency Comb

    NASA Astrophysics Data System (ADS)

    Yu, Youbin; Cheng, Xiaomin; Wang, Huaijun; Shi, Zhongtao; Zhao, Junwei; Ji, Fengmin; Yin, Zhi; Wang, Yajuan

    2015-01-01

    Continuous-variable (CV) entanglement frequency comb can be produced by enhanced Raman scattering in an above-threshold optical oscillator cavity in which a hexagonally-poled LiTaO3 crystal resides as a Raman gain medium. The Stokes and anti-Stokes Raman signals are enhanced by a coupled quasi-phase-matching optical parametric process and the entanglement natures among these Raman signals and pump are demonstrated by applying a sufficient inseparability criterion for CV entanglement. Such entanglement frequency comb source with different frequencies and continuously tunable frequency interval may be very significant for the applications in quantum communication and networks.

  1. Comparative reproduction of Varroa destructor in different types of Russian and Italian honey bee combs

    Technology Transfer Automated Retrieval System (TEKTRAN)

    We studied whether or not older comb supported less varroa reproduction in both Russian and Italian honey bees, whether Russian bees produced comb which inhibited varroa reproduction and whether comb foundation contained enough acaricides to influence varroa reproduction. The major differences foun...

  2. Calibration of an echelle spectrograph with an astro-comb: a laser frequency comb with very high repetition rate

    NASA Astrophysics Data System (ADS)

    Phillips, David F.; Glenday, Alex; Li, Chih-Hao; Furesz, Gabor; Benedick, Andrew J.; Chang, Guoqing N.; Chen, Li-Jin; Korzennik, Sylvain; Sasselov, Dimitar; Kaertner, Franz X.; Szentgyorgyi, Andrew; Walsworth, Ronald L.

    2012-09-01

    Searches for extrasolar planets using precision radial velocity (PRV) techniques are approaching Earth-like planet sensitivity, however require an improvement of one order of magnitude to identify earth-mass planets in the habitable zone of sun-like stars. A key limitation is spectrograph calibration. An astro-comb, an octave-spanning laser frequency comb and a Fabry-Pérot cavity, producing evenly spaced frequencies with large wavelength coverage, is a promising tool for improved wavelength calibration. We demonstrate the calibration of a high-resolution astrophysical spectrograph below the 1 m/s level in the 8000-9000 Å and 4200 Å spectral bands.

  3. Spectral and temporal characterization of a fused-quartz-microresonator optical frequency comb

    NASA Astrophysics Data System (ADS)

    Papp, Scott B.; Diddams, Scott A.

    2011-11-01

    We report on the fabrication of high-Q, fused-quartz microresonators and the parametric generation of a frequency comb with 36-GHz line spacing using them. We have characterized the intrinsic stability of the comb in both the time and frequency domains to assess its suitability for future precision metrology applications. Intensity autocorrelation measurements and line-by-line comb control reveal near-transform-limited picosecond pulse trains that are associated with good relative phase and amplitude stability of the comb lines. The comb's 36-GHz line spacing can be readily photodetected, which enables measurements of its intrinsic and absolute phase fluctuations.

  4. Target micro-displacement measurement by a "comb" structure of intensity distribution in laser plasma propulsion

    NASA Astrophysics Data System (ADS)

    Zheng, Z. Y.; Zhang, S. Q.; Gao, L.; Gao, H.

    2015-05-01

    A "comb" structure of beam intensity distribution is designed and achieved to measure a target displacement of micrometer level in laser plasma propulsion. Base on the "comb" structure, the target displacement generated by nanosecond laser ablation solid target is measured and discussed. It is found that the "comb" structure is more suitable for a thin film target with a velocity lower than tens of millimeters per second. Combing with a light-electric monitor, the `comb' structure can be used to measure a large range velocity.

  5. A stable frequency comb directly referenced to rubidium electromagnetically induced transparency and two-photon transitions

    SciTech Connect

    Hou, Dong; Wu, Jiutao; Zhang, Shuangyou; Ren, Quansheng; Zhang, Zhigang; Zhao, Jianye

    2014-03-17

    We demonstrate an approach to create a stable erbium-fiber-based frequency comb at communication band by directly locking the combs to two rubidium atomic transitions resonances (electromagnetically induced transparency absorption and two-photon absorption), respectively. This approach directly transfers the precision and stability of the atomic transitions to the comb. With its distinguishing feature of compactness by removing the conventional octave-spanning spectrum and f-to-2f beating facilities and the ability to directly control the comb's frequency at the atomic transition frequency, this stable optical comb can be widely used in optical communication, frequency standard, and optical spectroscopy and microscopy.

  6. Pretreatment of amphiphilic comb polymer surfaces dramatically affects protein adsorption.

    PubMed

    Zhang, Zhanping; Ma, Hongwei; Hausner, Douglas B; Chilkoti, Ashutosh; Beebe, Thomas P

    2005-01-01

    New applications in regenerative biotechnology require the ability to understand and control protein-surface interactions on micrometer and submicrometer length scales. Evidence presented here shows that micropatterned amphiphilic comb polymer films exhibit a pretreatment-dependent behavior with respect to protein adsorption for the proteins fibronectin, laminin, and for serum. A micropatterned surface, consisting of protein-reactive regions, separated by comb polymer, was created and tested for protein adsorption using the surface-sensitive imaging tool TOF-SIMS. Immersion of micropatterned surfaces in solutions of fibronectin or laminin resulted in uniform protein coverage on both the comb polymer and protein-reactive regions. However, preimmersion of similarly patterned surfaces in water for 2 h prior to protein incubation was found to dramatically improve the protein-resistant properties of the comb polymer regions. These results are consistent with poly(ethylene glycol) (PEG) side chain reorientation and/or hydration and poly(methyl methacrylate) (PMMA) backbone segregation away from the interface region. PMID:16283770

  7. Invited Article: A compact optically coherent fiber frequency comb

    NASA Astrophysics Data System (ADS)

    Sinclair, L. C.; Deschênes, J.-D.; Sonderhouse, L.; Swann, W. C.; Khader, I. H.; Baumann, E.; Newbury, N. R.; Coddington, I.

    2015-08-01

    We describe the design, fabrication, and performance of a self-referenced, optically coherent frequency comb. The system robustness is derived from a combination of an optics package based on polarization-maintaining fiber, saturable absorbers for mode-locking, high signal-to-noise ratio (SNR) detection of the control signals, and digital feedback control for frequency stabilization. The output is phase-coherent over a 1-2 μm octave-spanning spectrum with a pulse repetition rate of ˜200 MHz and a residual pulse-to-pulse timing jitter <3 fs well within the requirements of most frequency-comb applications. Digital control enables phase coherent operation for over 90 h, critical for phase-sensitive applications such as timekeeping. We show that this phase-slip free operation follows the fundamental limit set by the SNR of the control signals. Performance metrics from three nearly identical combs are presented. This laptop-sized comb should enable a wide-range of applications beyond the laboratory.

  8. Bonding of silicon scanning mirror having vertical comb fingers

    NASA Astrophysics Data System (ADS)

    Lee, Jin-Ho; Ko, Young-Chul; Choi, Byoung-So; Kim, Jong-Min; Jeon, Duk Young

    2002-09-01

    A 1500 μm × 1200 μm silicon scanning mirror has been fabricated by using anodic bonding and flip chip bonding. This scanning mirror is mainly composed of two structures having vertical comb fingers. By anodic bonding between the silicon wafer and the Pyrex glass substrate, and following deep inductively coupled plasma reactive ion etching (ICPRIE), isolated comb electrodes were fabricated at the lower structure. However, gold signal lines for electrical connection to the electrodes, which were inserted between silicon and Pyrex glass, were damaged during anodic bonding. This problem was solved by using the proposed processes and signal lines were successfully fabricated with the contact resistance below several tens of ohms. By flip chip bonding, the upper and lower structures having vertical comb fingers were assembled. Vertical comb fingers of two structures were aligned with a microscope and the frames of two structures were bonded at 300 °C for 20 s using the eutectic bonding material - electroplated AuSn. Finally, the scanning mirror was successfully fabricated and could be used for laser display as a galvanometric vertical scanner.

  9. Dislocations in mismatched layers of GaAsxP1 - x in between GaP as observed by low-temperature cathodoluminescence: Part II. Grown on (111) oriented substrates

    NASA Astrophysics Data System (ADS)

    Gustafsson, A.; Pistol, M.-E.; Gerling, M.; Samuelson, L.; Titze, H.

    1991-08-01

    Spectrally resolved low-temperature cathodoluminescence (CL) imaging has been performed on thin, 250 Å, mismatched layers of GaAsxP1-x in between bulk GaP. The layers were grown on (111) oriented substrates by metalorganic vapor phase epitaxy, with layers ranging from perfectly strained to totally relaxed. CL imaging has proven to be a very sensitive technique for the study of the onset of the formation of misfit dislocations and is therefore useful for determination of the critical thickness [A. Gustafsson, M.-E. Pistol, M. Gerling, L. Samuelson, M. R. Leys and H. Titze, J. Appl. Phys. 70, 1660 (1991)]. For the use of perfectly strained layers, growth on (111) oriented substrates can be of interest since the critical thickness predicted by the mechanical equilibrium theory [J. W. Matthews and A. E. Blakeslee, J. Cryst. Growth 27, 118 (1974)] is about twice that for growth on (001) oriented substrates. In this work we show that the dislocations involved in the strain relief for the growth of mismatched layers on (111) oriented substrates are of the perfect 60° type and that the experimental critical thickness agrees well with the value expected from the mechanical equilibrium theory.

  10. A frequency comb calibrated solar atlas

    NASA Astrophysics Data System (ADS)

    Molaro, P.; Esposito, M.; Monai, S.; Lo Curto, G.; González Hernández, J. I.; Hänsch, T. W.; Holzwarth, R.; Manescau, A.; Pasquini, L.; Probst, R. A.; Rebolo, R.; Steinmetz, T.; Udem, Th.; Wilken, T.

    2013-12-01

    Context. The solar spectrum is a primary reference for the study of physical processes in stars and their variation during activity cycles. High resolution spectra of the Sun are easily obtained from spatially selected regions of the solar disk, while those taken over the integrated disk are more problematic. However, a proxy can be obtained by using solar light reflected by small bodies of the solar system. Aims: In November 2010 an experiment with a prototype of a laser frequency comb (LFC) calibration system was performed with the HARPS spectrograph of the 3.6m ESO telescope at La Silla during which high signal-to-noise spectra of the Moon were obtained. We exploit those Echelle spectra to study a portion of the optical integrated solar spectrum and in particular to determine the solar photospheric line positions. Methods: The DAOSPEC program is used to measure solar line positions through Gaussian fitting in an automatic way. The solar spectra are calibrated both with an LFC and a Th-Ar. Results: We first apply the LFC solar spectrum to characterize the CCDs of the HARPS spectrograph. The comparison of the LFC and Th-Ar calibrated spectra reveals S-type distortions on each order along the whole spectral range with an amplitude of ±40 m s-1 . This confirms the pattern found in the first LFC experiment on a single order and extends the detection of the distortions to the whole analyzed region revealing that the precise shape varies with wavelength. A new data reduction is implemented to deal with CCD pixel inequalities to obtain a wavelength corrected solar spectrum. By using this spectrum we provide a new LFC calibrated solar atlas with 400 line positions in the range of 476-530, and 175 lines in the 534-585 nm range corresponding to the LFC bandwidth. The new LFC atlas is consistent on average with that based on FTS solar spectra, but it improves the accuracy of individual lines by a significant factor reaching a mean value of ≈10 m s-1 . Conclusions: The

  11. Comparative efficacy of commercial combs in removing head lice (Pediculus humanus capitis) (Phthiraptera: Pediculidae).

    PubMed

    Gallardo, Anabella; Toloza, Ariel; Vassena, Claudia; Picollo, María Inés; Mougabure-Cueto, Gastón

    2013-03-01

    The use of a fine comb for removing lice from the head of the human host is a relevant tool both in the diagnosis of infestations and as part of an integrated control strategy of head lice. The effectiveness of a fine comb depends, in part, on the design and material they are built. The aim of this study was to compare in vivo the efficacy of metal and plastic combs that are currently used in the removal of head lice and eggs worldwide. The space between comb teeth and the length was 0.23 and 13 mm in KSL® plastic, 0.3 and 10.7 mm in NOPUCID® plastic, 0.15 and 31 mm in KSL® metal and 0.09 and 37 mm in ASSY® metal. The assays were performed comparing the combs in pairs: (a) KSL® vs. NOPUCID® plastic combs, (b) KSL® vs. ASSY® metal combs and (c) KSL® plastic comb vs. ASSY® metal comb. The most effective plastic comb was KSL®, removing a higher number of individuals of all stages. The most effective metal comb was ASSY®, removing more insects of all stages (except adults). The comparative test between KSL® plastic and ASSY® metal showed that ASSY® was the most effective in removing head lice and their eggs. PMID:23212391

  12. Mycological examinations on the fungal flora of the chicken comb.

    PubMed

    Gründer, S; Mayser, P; Redmann, T; Kaleta, E F

    2005-03-01

    A total of 500 combs of adult chickens from two different locations in Germany (Hessen and Schleswig-Holstein) were clinically and mycologically examined. The chickens came from three battery cages (n = 79), one voliere system (n=32), six flocks maintained on deep litter (n = 69) and 12 flocks kept on free outdoor range (n=320). Twenty-two of the 500 chicken combs (4.4%) were found to have clinical signs: only non-specific lesions neither typical of mycosis nor of avian pox such as desquamation with crust formation, yellow to brown or black dyschromic changes, alopecia in the surrounding area and moist inflammation. Only seven of the 22 clinically altered combs showed a positive mycological result; the non-pathogenic and geophilic Trichophyton terrestre in one case and non-pathogenic yeast in six cases. The following fungi were seen in the different housing systems: 13 dermatophytes (2.6% of 500 samples): 12 x T. terrestre, 1 x Trichophyton mentagrophytes, 11 isolates of Chrysosporium georgiae (2.2% of 500 samples) and 149 isolates of yeasts (29.8%): Malassezia sympodialis: n = 52, Kloeckera apiculata: n = 33, Trichosporon capitatum (syn. Geotrichum capitatum): n = 23, Trichosporon cutaneum/Trichosporon mucoides: n = 12, Trichosporon inkin (syn. Sarcinosporon inkin): n = 8 and Candida spp.: n = 21, including pathogenic or possibly pathogenic species: Candida albicans: n = 3, Candida famata: n = 4, Candida guilliermondii: n = 3, Candida lipolytica: n = 3, Candida dattila: n = 2 and one isolate each of Candida glabrata, Candida parapsilosis, Candida aaseri, Candida catenulata sive brumpti, Candida fructus and Candida kefyr sive pseudotropicalis. There is no stringent correlation between the clinical symptoms diagnosed on the chicken combs and the species of yeasts isolated. The causative agent of favus in chickens, Trichophyton gallinae, and the saprophytic yeast in pigeons, Cr. neoformans were not isolated. The most frequently isolated yeasts M. sympodialis and

  13. Dual Comb Fourier Transform Spectroscopy in the Green Region

    NASA Astrophysics Data System (ADS)

    Knize, R. J.; Bernhardt, B.; Picqué, N.; Hänsch, T. W.

    2010-06-01

    Laser combs in combination with other advancing tools of laser science, nonlinear optics, photonics, and electronic signal processing have the potential to vastly enhance the range and capabilities of molecular laser spectroscopy. The high versatility of frequency comb sources can indeed harness new techniques for ultra-rapid and ultra-sensitive recording of complex molecular spectra. The recent proof-of-principle demonstrations of dual comb Fourier transform spectroscopy have mostly been carried out in the near-infrared region, around 1.0 and 1.5 μm. The mode-locked ytterbium- or erbium-doped fiber femtosecond laser systems emitting in this range indeed require few adjustment thanks to their guided light and permit reliable unattended operation. With expanded wavelength coverage and continued improvements in speed and sensitivity, dual comb spectroscopy should find use as a novel, time-domain spectroscopic analytical tool. As far as molecular spectroscopy is concerned, the mid-infrared and visible-ultraviolet wavelength regions show both the potential for specificity and sensitivity for tracing molecules. In particular, the visible-ultraviolet region complements the mid-infrared molecular fingerprint range, as it provides access to many electronic transitions, in particular belonging to reactive species. In this contribution, we report on our progress in the implementation of dual comb spectroscopy in the 520 nm green region. We present preliminary results on a powerful new sensitive ultra-rapid tool for linear rovibronic absorption spectroscopy, based on frequency-doubled ytterbium-doped fiber lasers and we discuss its intriguing prospects for spectroscopy of short lived transient species.

  14. Dynamics of dual-polarization VCSEL-based optical frequency combs under optical injection locking.

    PubMed

    Prior, E; de Dios, C; Criado, R; Ortsiefer, M; Meissner, P; Acedo, P

    2016-09-01

    The present experimental work studies the dynamics of dual-polarization optical frequency combs (OFCs) based on gain switching (GS) vertical-cavity surface-emitting laser (VCSEL) diodes under optical injection locking (OIL). This study presents two main results. First, we have obtained an overall comb formed by two orthogonally polarized sub-combs with comparable span and power. The overall comb shows enhanced optical span and flatness and high coherence between its modes. The second result is that we have been able to control the polarization state of the overall comb by tuning the polarization state of the injected light by locking the same single teeth of the comb. This produces an overall comb with single polarization that is parallel or orthogonal. These are novel findings that provide for the development of efficient and compact OFCs based on GS VCSEL sources with versatile polarization dynamics. PMID:27607978

  15. Stabilized chip-scale Kerr frequency comb via a high-Q reference photonic microresonator

    NASA Astrophysics Data System (ADS)

    Lim, Jinkang; Huang, Shu-Wei; Vinod, Abhinav K.; Mortazavian, Parastou; Yu, Mingbin; Kwong, Dim-Lee; Savchenkov, Anatoliy A.; Matsko, Andrey B.; Maleki, Lute; Wong, Chee Wei

    2016-08-01

    We stabilize a chip-scale Si3N4 phase-locked Kerr frequency comb via locking the pump laser to an independent stable high-Q reference microresonator and locking the comb spacing to an external microwave oscillator. In this comb, the pump laser shift induces negligible impact on the comb spacing change. This scheme is a step towards miniaturization of the stabilized Kerr comb system as the microresonator reference can potentially be integrated on-chip. Fractional instability of the optical harmonics of the stabilized comb is limited by the microwave oscillator used for comb spacing lock below 1 s averaging time and coincides with the pump laser drift in the long term.

  16. Investigation on electro-optic optical comb generation with higher spectral resolution and bandwidth

    NASA Astrophysics Data System (ADS)

    Sakamoto, Takahide; Morohashi, Isao

    2016-03-01

    With a use of electro-optic modulator based comb generator, ultra-wideband optical comb is stably and flexibly synthesized from a continuous-wave light. Larger modulation depth at a higher repetition rate would proportionally enhance bandwidth of the generated comb. Practically, however, achievable modulation depth is limited by available output power of microwave amplifiers. In addition, the repetition rate, i.e. comb spacing, is determined by system-side requirements. For example, frequency spacing of the generated comb should fit to the wavelength grid of optical fiber networks. Narrower frequency spacing is requested for photonic measurements assisted by advanced electrical signal processing based on low-speed electronics. In this paper, through numerical analysis, we propose and discuss configurations of serially cascaded Mach-Zehnder modulator-based flat comb generators, aiming for optical comb generation satisfying both higher bandwidth and narrower frequency spacing.

  17. Sex Offenders.

    ERIC Educational Resources Information Center

    Hayes, Susan

    1991-01-01

    This paper on the problem of sex offending among individuals with intellectual disabilities examines the incidence of this problem, characteristics of intellectually disabled sex offenders, determination of whether the behavior is a paraphilia or functional age-related behavior, and treatment options, with emphasis on the situation in New South…

  18. Sex Therapy

    ERIC Educational Resources Information Center

    Hogan, Douglas

    1977-01-01

    Notes that no single theory of psychotherapy dominates the field of sex therapy. On one hand, sex therapy is not subject to the rigid dogmas of many areas of psychotherapy. But on the other hand, many techniques are invented at the whim of clinicians with no basis in theory. (Author/AM)

  19. [Sex education, sex behavior, contraception].

    PubMed

    Borkenstein, M; Schwingshandl, J; Kuttnig, M; Limbert, C

    1991-01-01

    Sexual behavior has changed during the last decades. Teenage fertility rate, and the number of gonococcal infections are both extremely high; the incidence of HIV-infections is increasing. Preventive measures include sex education. Sex education may help the adolescents to identify their own goals for sexual behavior, to avoid unintended and unwanted pregnancy, and to avoid sexually transmitted diseases. PMID:1945474

  20. Safe sex.

    PubMed

    Mukherjee, G; Ghosh, T K

    1994-01-01

    The main objectives of health care for people with AIDS are to help them adjust to changing sexual status and to provide them with information on safe sex. Sections consider the risks of various types of sexual activity and safe sex education. With regard to the risk of transmitting or contracting HIV, sexual activities may be high risk, medium risk, low risk, or no risk. High-risk activities include unprotected anal or vaginal intercourse, oral-anal sexual contact, sharing sex toys, and traumatic sexual activity. Medium-risk activities include anal and vaginal intercourse using a latex condom with or without spermicide, and sex using a vaginal diaphragm or contraceptive vaginal sponge. Oral sex on a woman or oral sex on a man without ejaculation into the mouth are low-risk activities. Mutual masturbation, erotic touching, caressing and massage, kissing and non-genital licking pose no risk of infection. All general practitioners and family physicians should teach about safe sex. Prevention messages may be conveyed through individual and social counseling as well as with printed media and other forms of mass media. Messages should definitely reach prostitutes and brothel owners, as well as pre-pubertal children and older youths. PMID:8207282

  1. Calibration of an Astrophysical Spectrograph with an Astro-comb

    NASA Astrophysics Data System (ADS)

    Phillips, David F.; Glenday, Alex; Li, Chih-Hao; Cramer, Claire; Korzennik, Sylvain; Noah Chang, Guoqing; Chen, Li-Jin; Benedick, Andrew; Kaertner, Franz X.; Sasselov, Dimitar; Szentgyorgyi, Andrew; Walsworth, Ronald L.

    2010-03-01

    Searches for extrasolar planets using the periodic Doppler shift of stellar lines are approaching Earth-like planet sensitivity. To find a 1-Earth-mass planet in an Earth-like orbit, an order of magnitude improvement in state-of-the-art radial velocity spectroscopy is necessary. An astro-comb, the combination of an ocatve-spanning laser frequency comb with a Fabry-Perot cavity, producing evenly spaced frequency markers with the potential for large wavelength coverage is a promising avenue towards improved wavelength calibration. Here we demonstrate the calibration of a high-resolution astrophysical spectrograph below the 1 m/s level in the 800-900 nm spectral band using an octave-spanning Ti:Sapphire laser and an ultra-low dispersion Fabry-Perot filter cavity adjusted for a mode spacing of approximately 31 GHz. Modeling of spectrograph response function and overall system stability and reproducibility will be described.

  2. Optical Frequency Comb Spectroscopy of Rare Earth Atoms

    NASA Astrophysics Data System (ADS)

    Swiatlowski, Jerlyn; Palm, Christopher; Joshi, Trinity; Montcrieffe, Caitlin; Jackson Kimball, Derek

    2013-05-01

    We discuss progress in our experimental program to employ optical-frequency-comb-based spectroscopy to understand the complex spectra of rare-earth atoms. We plan to carry out systematic measurements of atomic transitions in rare-earth atoms to elucidate the energy level structure and term assignment and determine presently unknown atomic state parameters. This spectroscopic information is important in view of the increasing interest in rare-earth atoms for atomic frequency standards, in astrophysical investigations of chemically peculiar stars, and in tests of fundamental physics (tests of parity and time-reversal invariance, searches for time variation of fundamental constants, etc.). We are presently studying the use of hollow cathode lamps as atomic sources for two-photon frequency comb spectroscopy. Supported by the National Science Foundation under grant PHY-0958749.

  3. Active laser ranging with frequency transfer using frequency comb

    NASA Astrophysics Data System (ADS)

    Zhang, Hongyuan; Wei, Haoyun; Yang, Honglei; Li, Yan

    2016-05-01

    A comb-based active laser ranging scheme is proposed for enhanced distance resolution and a common time standard for the entire system. Three frequency combs with different repetition rates are used as light sources at the two ends where the distance is measured. Pulse positions are determined through asynchronous optical sampling and type II second harmonic generation. Results show that the system achieves a maximum residual of 379.6 nm and a standard deviation of 92.9 nm with 2000 averages over 23.6 m. Moreover, as for the frequency transfer, an atom clock and an adjustable signal generator, synchronized to the atom clock, are used as time standards for the two ends to appraise the frequency deviation introduced by the proposed system. The system achieves a residual fractional deviation of 1.3 × 10-16 for 1 s, allowing precise frequency transfer between the two clocks at the two ends.

  4. Envelope, group and phase velocities in a nested frequency comb

    NASA Astrophysics Data System (ADS)

    Masuda, Koji; Hendrie, James; Diels, Jean-Claude; Arissian, Ladan

    2016-04-01

    Fabry–Pérot etalons have been traditionally used in a laser cavity to tune the optical frequency. In this work we present the generation of interwoven frequency combs with insertion of an intracavity Fabry–Pérot in a mode-locked laser. A high frequency comb is generated by insertion of an uncoated (low finesse) Fabry–Pérot inside the laser cavity. The intracavity Fabry–Pérot acquires a high finesse from the laser cavity and the velocity of the pulses in the Fabry–Pérot is affected by the laser cavity length, gain and losses, with the dielectric group velocity dk/dΩ playing only a minor role. The output characteristics are explained by the condition that the radiation is simultaneously resonant with the etalon and the laser cavity.

  5. Envelope, group and phase velocities in a nested frequency comb

    NASA Astrophysics Data System (ADS)

    Masuda, Koji; Hendrie, James; Diels, Jean-Claude; Arissian, Ladan

    2016-05-01

    Fabry–Pérot etalons have been traditionally used in a laser cavity to tune the optical frequency. In this work we present the generation of interwoven frequency combs with insertion of an intracavity Fabry–Pérot in a mode-locked laser. A high frequency comb is generated by insertion of an uncoated (low finesse) Fabry–Pérot inside the laser cavity. The intracavity Fabry–Pérot acquires a high finesse from the laser cavity and the velocity of the pulses in the Fabry–Pérot is affected by the laser cavity length, gain and losses, with the dielectric group velocity dk/dΩ playing only a minor role. The output characteristics are explained by the condition that the radiation is simultaneously resonant with the etalon and the laser cavity.

  6. Local comb generation in nonlinear TiN superconducting resonators

    NASA Astrophysics Data System (ADS)

    Pappas, David; Vissers, Michael R.; Erickson, Robert; Sandberg, Martin; Gao, Jiansong

    2014-03-01

    Low loss superconducting nonlinear resonators are extensively used for qubit readout as well as photon detectors. These devices are typically capacitively coupled to a launch line. When driven at high power, a shift in resonant frequency is observed due to the kinetic inductance of the TiN superconductor. At higher power, the resonant frequency mixes with the drive tone to produce a series of peaks that are observed to be equally spaced at the detuning frequency, i.e. a ``local comb.'' The full circuit analysis of this system is derived. The renormalized resonant frequency is obtained and the local comb is derived from a first order successive approximation. Work suppported by DARPA, ARO, and NIST.

  7. Chemical detection with hyperspectral lidar using dual frequency combs.

    PubMed

    Boudreau, Sylvain; Levasseur, Simon; Perilla, Carlos; Roy, Simon; Genest, Jérôme

    2013-03-25

    High-resolution spectral lidar measurements using dual frequency combs as a source is presented. The technique enables the range-resolved measurement of fine spectral features, such as gas absorption lines, provided that a suitable scatterer is present in the scene. Measurements of HCN absorption lines at 20 meters are presented, with a water droplet cloud and a diffusely reflective surface as scatterers. PMID:23546124

  8. A Novel Nit Comb Concept Using Ultrasound Actuation: Preclinical Evaluation.

    PubMed

    Burgess, Mark N; Brunton, Elizabeth R; Burgess, Ian F

    2016-01-01

    Nit combing and removal of head louse, Pediculus humanus capitis De Geer (Anoplura: Pediculidae), eggs is a task made more difficult because "nit combs" vary in efficiency. There is currently no evidence that the binding of the eggshell to the hair can be loosened chemically and few hair treatments improve the slip of the louse eggs along the hair. Ultrasound, applied through the teeth of a nit comb, may facilitate the flow of fluids into the gap between the hair shaft and the tube of fixative holding louse eggs in place to improve lubrication. Ultrasound alone had little effect to initiate sliding, requiring a force of 121.5 ± 23.8 millinewtons (mN) compared with 125.8 ± 18.0 mN without ultrasound, but once the egg started to move it made the process easier. In the presence of a conditioner-like creamy lotion, ultrasound reduced the Peak force required to start movement to 24.3 ± 8.8 mN from 50.4 ± 13.0 mN without ultrasound. In contrast, some head louse treatments made removal of eggs more difficult, requiring approximately twice the Peak force to initiate movement compared with dry hair in the absence of ultrasound. However, following application of ultrasound, the forces required to initiate movement increased for an essential oil product, remained the same for isopropyl myristate and cyclomethicone, and halved for 4% dimeticone lotion. Fixing the nit comb at an estimated angle of 16.5° to the direction of pull gave an optimum effect to improve the removal process when a suitable lubricant was used. PMID:26545717

  9. Generation of a frequency comb and applications thereof

    DOEpatents

    Hagmann, Mark J; Yarotski, Dmitry A

    2013-12-03

    Apparatus for generating a microwave frequency comb (MFC) in the DC tunneling current of a scanning tunneling microscope (STM) by fast optical rectification, cause by nonlinearity of the DC current vs. voltage curve for the tunneling junction, of regularly-spaced, short pulses of optical radiation from a focused mode-locked, ultrafast laser, directed onto the tunneling junction, is described. Application of the MFC to high resolution dopant profiling in semiconductors is simulated. Application of the MFC to other measurements is described.

  10. Precision Spectroscopy of Hydrogen and Femtosecond Laser Frequency Combs

    NASA Astrophysics Data System (ADS)

    Udem, Thomas

    2006-03-01

    A femtosecond frequency comb is a simple and compact tool that allows the phase coherent connection of the radio frequency domain (below 100 GHz) with the optical domain (above 200 THz). It greatly simplified high precision optical frequency measurements and provides the long awaited clockwork mechanism for an all-optical atomic clock. We have used such a frequency comb to measure the absolute frequency of the 1S-2S two-photon transition in atomic hydrogen, i.e. comparing it with the Cs ground state hyperfine splitting. By comparing data taken in 2003 with earlier measurements in 1999 we can set an upper limit on the variation of the 1S-2S transition frequency of (-29 ±57) Hz within 44 months. To derive limits on the drift rates of fundamental constant such as the fine structure constant, we combine these measurements with other optical frequency measurements in Hg^+ and in Yb^+ performed at NIST, Boulder/USA and at PTB, Braunschweig/Germany respectively. This combined method gives precise and separate restrictions for the fractional time variation of the fine structure constant and the Cs nuclear magnetic moment measured in Bohr magnetons. The latter is a measure of the drift rate of the strong interaction. We also report on efforts to convert the frequency comb technology to much shorter wavelength. Based on intra cavity high harmonic generation an XUV (up to 60 nm) frequency comb is generated with a repetition rate of more than 100 MHz useful for high resolution laser spectroscopy in this region.

  11. Safe sex

    MedlinePlus

    ... and discuss your sexual histories Don't feel forced into having sex Don't have sexual contact ... or polyurethane condoms. Use condoms for all vaginal, anal, and oral intercourse. The condom should be in ...

  12. Sex work and sex trafficking.

    PubMed

    Ditmore, M; Saunders, P

    1998-01-01

    Preventing HIV infection and other sexually transmitted diseases (STDs), as well as sexual and physical violence, are major occupational health and safety concerns for prostitutes. Considerable evidence shows that anti-prostitution laws facilitate violence and abuse against prostitutes and may increase their risk of contracting HIV/STDs. For example, police often take advantage of existing laws against prostitution to demand money or sex. In general, the strict enforcement of anti-prostitution laws marginalizes prostitutes from services which could help them avoid abuse and promotes an environment in which prostitutes must take risks to avoid detection and arrest. One strategy to improve prostitutes' lives would therefore be to remove laws which prevent them from working safely and from travelling abroad to work legally. Projects in which prostitutes are actively involved have helped break down stereotypes against prostitutes, while police-sex worker liaison projects in Scotland and Australia have led to higher levels of reporting of crimes against prostitutes. The Network of Sex Work Projects (NSWP), an organization which links sex worker health programs around the world, has found that the incidence of HIV/STDs among prostitutes is lowest when they have control over their work conditions; access to condoms, lubricants, and other safe sex materials; and respect of their basic human and legal rights. People need to understand that consensual involvement in sex work is different from forced sex trafficking. PMID:12348692

  13. A portable dual frequency comb spectrometer for atmospheric applications

    NASA Astrophysics Data System (ADS)

    Cossel, Kevin; Waxman, Eleanor; Truong, Gar-Wing; Giorgetta, Fabrizio; Swann, William; Rieker, Gregory; Coddington, Ian; Newbury, Nathan

    2016-04-01

    Dual frequency comb (DFC) spectroscopy is a new technique that combines broad spectral bandwidth, high spectral resolution, rapid data acquisition, and high sensitivity. In addition, unlike standard Fourier-transform spectroscopy, it has an almost ideal instrument lineshape function, does not require recalibration, and has no moving parts. These features make DFC spectroscopy well suited for accurate measurements of multiple species simultaneously. Because the frequency comb lasers can be well collimated, such a system can be used for long open-path measurements with path lengths ranging from hundreds of meters to several kilometers. This length scale bridges the gap between point measurements and satellite-based measurements and is ideal for providing information about local sources and quanitfying emissions. Here we show a fully portable DFC spectrometer operating over a wide spectral region in the near-infrared (about 1.5-2.1 μm or 6670-4750 cm‑1 sampled at 0.0067 cm‑1) and across several different open-air paths. The current spectrometer fits in about a 500 L volume and has low power consumption. It provides simultaneous measurements of CO2, CH4, and water isotopes with a time resolution of seconds to minutes. We will provide an introduction to dual frequency comb spectroscopy and then discuss the design and performance of the system.

  14. Applications of Cavity-Enhanced Direct Frequency Comb Spectroscopy

    NASA Astrophysics Data System (ADS)

    Cossel, Kevin C.; Adler, Florian; Maslowski, Piotr; Ye, Jun

    2010-06-01

    Cavity-enhanced direct frequency comb spectroscopy (CE-DFCS) is a unique technique that provides broad bandwidth, high resolution, and ultra-high detection sensitivities. This is accomplished by combining a femtosecond laser based optical frequency comb with an enhancement cavity and a broadband, multichannel imaging system. These systems are capable of simultaneously recording many terahertz of spectral bandwidth with sub-gigahertz resolution and absorption sensitivities of 1×10-7 cm-1 Hz-1/2. In addition, the ultrashort pulses enable efficient nonlinear processes, which makes it possible to reach spectral regions that are difficult to access with conventional laser sources. We will present an application of CE-DFCS for trace impurity detection in the semiconductor processing gas arsine near 1.8 μm and the development of a high-power, mid-infrared frequency comb for breath analysis in the 2.8-4.8 μm region. M. J. Thorpe, K. D. Moll, R. J. Jones, B. Safdi, and J. Ye. Science 311, 1595-1599 (2006) F. Adler, M. J. Thorpe, K. C. Cossel, and J. Ye. Annu. Rev. Anal. Chem. 3, 175-205 (2010) F. Adler, K. C. Cossel, M. J. Thorpe, I. Hartl, M. E. Fermann, and J. Ye. Opt. Lett. 34, 1330-1332 (2009)

  15. Comb-locked cavity ring-down spectrometer

    NASA Astrophysics Data System (ADS)

    Gatti, Davide; Sala, Tommaso; Gotti, Riccardo; Cocola, Lorenzo; Poletto, Luca; Prevedelli, Marco; Laporta, Paolo; Marangoni, Marco

    2015-02-01

    Extreme frequency accuracy and high sensitivity are obtained with a novel comb-locked cavity-ring-down spectrometer operating in the near-infrared from 1.5 to 1.63 μm. A key feature of our approach is the tight frequency locking of the probe laser to the comb, ensuring very high reproducibility and accuracy to the frequency axis upon scanning the comb repetition rate, as well as an efficient light injection into a length-swept high-finesse passive cavity containing the gas sample. Spectroscopic tests on the (30012) ← (00001) P14e line of CO2 at ˜1.57 μm demonstrate an accuracy of ˜17 kHz on the line center frequency in a Doppler broadening regime over the time scale of about 5 min, corresponding to four consecutive spectral scans of the absorption line. Over a single scan, which consists of 1500 spectral points over 75 s, the limit of detection is as low as 5.7 × 10-11 cm-1.

  16. Coherent Raman spectro-imaging with laser frequency combs.

    PubMed

    Ideguchi, Takuro; Holzner, Simon; Bernhardt, Birgitta; Guelachvili, Guy; Picqué, Nathalie; Hänsch, Theodor W

    2013-10-17

    Advances in optical spectroscopy and microscopy have had a profound impact throughout the physical, chemical and biological sciences. One example is coherent Raman spectroscopy, a versatile technique interrogating vibrational transitions in molecules. It offers high spatial resolution and three-dimensional sectioning capabilities that make it a label-free tool for the non-destructive and chemically selective probing of complex systems. Indeed, single-colour Raman bands have been imaged in biological tissue at video rates by using ultra-short-pulse lasers. However, identifying multiple, and possibly unknown, molecules requires broad spectral bandwidth and high resolution. Moderate spectral spans combined with high-speed acquisition are now within reach using multichannel detection or frequency-swept laser beams. Laser frequency combs are finding increasing use for broadband molecular linear absorption spectroscopy. Here we show, by exploring their potential for nonlinear spectroscopy, that they can be harnessed for coherent anti-Stokes Raman spectroscopy and spectro-imaging. The method uses two combs and can simultaneously measure, on the microsecond timescale, all spectral elements over a wide bandwidth and with high resolution on a single photodetector. Although the overall measurement time in our proof-of-principle experiments is limited by the waiting times between successive spectral acquisitions, this limitation can be overcome with further system development. We therefore expect that our approach of using laser frequency combs will not only enable new applications for nonlinear microscopy but also benefit other nonlinear spectroscopic techniques. PMID:24132293

  17. Dual-Colored DNA Comb Polymers for Single Molecule Rheology

    NASA Astrophysics Data System (ADS)

    Mai, Danielle; Marciel, Amanda; Schroeder, Charles

    2014-03-01

    We report the synthesis and characterization of branched biopolymers for single molecule rheology. In our work, we utilize a hybrid enzymatic-synthetic approach to graft ``short'' DNA branches to ``long'' DNA backbones, thereby producing macromolecular DNA comb polymers. The branches and backbones are synthesized via polymerase chain reaction with chemically modified deoxyribonucleotides (dNTPs): ``short'' branches consist of Cy5-labeled dNTPs and a terminal azide group, and ``long'' backbones contain dibenzylcyclooctyne-modified (DBCO) dNTPs. In this way, we utilize strain-promoted, copper-free cycloaddition ``click'' reactions for facile grafting of azide-terminated branches at DBCO sites along backbones. Copper-free click reactions are bio-orthogonal and nearly quantitative when carried out under mild conditions. Moreover, comb polymers can be labeled with an intercalating dye (e.g., YOYO) for dual-color fluorescence imaging. We characterized these materials using gel electrophoresis, HPLC, and optical microscopy, with atomic force microscopy in progress. Overall, DNA combs are suitable for single molecule dynamics, and in this way, our work holds the potential to improve our understanding of topologically complex polymer melts and solutions.

  18. Progress Report on a Portable TI:SAPPHIRE Comb Laser with Frequencies Referring to Cesium Atom Two-Photon Transitions

    NASA Astrophysics Data System (ADS)

    Cheng, Wang-Yau; Wu, Chien-Ming; Liu, Tz-Wei; Chen, Yo-Huan

    2010-06-01

    A portable Ti:sapphire comb laser would contribute significantly to generalize comb-laser applications, such as the astro-comb missions or other interdisciplinary collaborations. To develop a portable comb laser, three barriers lie ahead: one is to miniaturize and robotize the frequency reference system of the comb laser; the second is to ensure the long-term frequency accuracy without satellite connection, and the third is to miniaturize the pumping laser system. We developed two hand-size cesium-stabilized diode lasers at 822 nm and 884 nm to serve as frequency references for a comb laser and we carried out a comb-laser-based CPT experiment with one single cesium cell that might offer a locking procedure for long-term comb laser accuracy. We will also report our plans and progress on a fiber laser pumped Ti:sapphire comb laser.

  19. Solar oscillations and the search for Venus enabled by a laser frequency comb

    NASA Astrophysics Data System (ADS)

    Phillips, David F.; Glenday, Alexander G.; Li, Chih-Hao; Langellier, Nicholas; Chang, Guoqing; Furesz, Gabor; Kaertner, Franz X.; Sasselov, Dimitar; Szentgyorgyi, Andrew; Walsworth, Ronald L.

    2015-05-01

    We have recently demonstrated sub-m/s sensitivity in measuring the radial velocity (RV) between the Earth and Sun using a simple, home-built solar telescope feeding the HARPS-N spectrograph at the Italian National Telescope calibrated with our green astro-comb. The green astro-comb is a laser frequency comb optimized for calibrating astrophysical spectrographs. We plan, in the coming year, to use the astro-comb calibrated spectrograph and solar telescope to detect the solar RV signal induced by Venus and thus demonstrate sensitivity of these instruments to detect terrestrial exoplanets. Here, we will present the astro-comb, results from the astro-comb calibrating the HARPS-N exoplanet searcher spectrograph, solar RV stability and plans for observing the signature of Venus.

  20. Direct generation of optical frequency combs in χ(2) nonlinear cavities

    NASA Astrophysics Data System (ADS)

    Mosca, Simona; Ricciardi, Iolanda; Parisi, Maria; Maddaloni, Pasquale; Santamaria, Luigi; De Natale, Paolo; De Rosa, Maurizio

    2016-06-01

    Quadratic nonlinear processes are currently exploited for frequency comb transfer and extension from the visible and near infrared regions to other spectral ranges where direct comb generation cannot be accomplished. However, frequency comb generation has been directly observed in continuously pumped quadratic nonlinear crystals placed inside an optical cavity. At the same time, an introductory theoretical description of the phenomenon has been provided, showing a remarkable analogy with the dynamics of third-order Kerr microresonators. Here, we give an overview of our recent work on χ(2) frequency comb generation. Furthermore, we generalize the preliminary three-wave spectral model to a many-mode comb and present a stability analysis of different cavity field regimes. Although our work is a very early stage, it lays the groundwork for a novel class of highly efficient and versatile frequency comb synthesizers based on second-order nonlinear materials.

  1. Direct fiber comb stabilization to a gas-filled hollow-core photonic crystal fiber.

    PubMed

    Wu, Shun; Wang, Chenchen; Fourcade-Dutin, Coralie; Washburn, Brian R; Benabid, Fetah; Corwin, Kristan L

    2014-09-22

    We have isolated a single tooth from a fiber laser-based optical frequency comb for nonlinear spectroscopy and thereby directly referenced the comb. An 89 MHz erbium fiber laser frequency comb is directly stabilized to the P(23) (1539.43 nm) overtone transition of (12)C(2)H(2) inside a hollow-core photonic crystal fiber. To do this, a single comb tooth is isolated and amplified from 20 nW to 40 mW with sufficient fidelity to perform saturated absorption spectroscopy. The fractional stability of the comb, ~7 nm away from the stabilized tooth, is shown to be 6 × 10(-12) at 100 ms gate time, which is over an order of magnitude better than that of a comb referenced to a GPS-disciplined Rb oscillator. PMID:25321837

  2. Redescription of Synthesium pontoporiae n. comb. with notes on S. tursionis and S. seymouri n. comb. (Digenea: Brachycladiidae Odhner, 1905).

    PubMed

    Marigo, Juliana; Vicente, Ana Carolina Paulo; Valente, Ana Luisa Schifino; Measures, Lena; Santos, Cláudia Portes

    2008-04-01

    Synthesium pontoporiae n. comb. is redescribed, together with Synthesium tursionis and Synthesium seymouri n. comb.; the parasites were obtained from stranded and accidentally caught cetaceans. The sucker ratio (ratio between widths of the oral and ventral suckers) in S. pontoporiae was 1:1.8-3.0 (mean 1:2.2); in S. tursionis was 1:0.8-1.2; and in S. seymouri was 1:0.5-0.7. Synthesium pontoporiae differed from its congeners by additional diagnostic characters, including: oval to lobed testes; small cirrus with pyriform proximal region and flexible, tubular distal region formed by evagination of ejaculatory duct; and vitellarium in small follicles extending from the level of the seminal vesicle to the posterior extremity of the body and not forming dendritic radial bunches. Data on the morphology of adult S. pontoporiae and S. tursionis were inferred from confocal laser microscopical observations. PMID:18564752

  3. Coherent mid-infrared frequency combs in silicon-microresonators in the presence of Raman effects.

    PubMed

    Griffith, Austin G; Yu, Mengjie; Okawachi, Yoshitomo; Cardenas, Jaime; Mohanty, Aseema; Gaeta, Alexander L; Lipson, Michal

    2016-06-13

    We demonstrate the first low-noise mid-IR frequency comb source using a silicon microresonator. Our observation of strong Raman scattering lines in the generated comb suggests that interplay between Raman and four-wave mixing plays a role in the generated low-noise state. In addition, we characterize, the intracavity comb generation dynamics using an integrated PIN diode, which takes advantage of the inherent three-photon absorption process in silicon. PMID:27410323

  4. Broadband Mid-Infrared Comb-Resolved Fourier Transform Spectroscopy

    NASA Astrophysics Data System (ADS)

    Lee, Kevin; Mills, Andrew; Mohr, Christian; Jiang, Jie; Fermann, Martin; Maslowski, Piotr

    2014-06-01

    We report on a comb-resolved, broadband, direct-comb spectroscopy system in the mid-IR and its application to the detection of trace gases and molecular line shape analysis. By coupling an optical parametric oscillator (OPO), a 100 m multipass cell, and a high-resolution Fourier transform spectrometer (FTS), sensitive, comb-resolved broadband spectroscopy of dilute gases is possible. The OPO has radiation output at 3.1-3.7 and 4.5-5.5 μm. The laser repetition rate is scanned to arbitrary values with 1 Hz accuracy around 417 MHz. The comb-resolved spectrum is produced with an absolute frequency axis depending only on the RF reference (in this case a GPS disciplined oscillator), stable to 1 part in 10^9. The minimum detectable absorption is 1.6x10-6 wn Hz-1/2. The operating range of the experimental setup enables access to strong fundamental transitions of numerous molecular species for applications based on trace gas detection such as environmental monitoring, industrial gas calibration or medical application of human breath analysis. In addition to these capabilities, we show the application for careful line shape analysis of argon-broadened CO band spectra around 4.7 μm. Fits of the obtained spectra clearly illustrate the discrepancy between the measured spectra and the Voigt profile (VP), indicating the need to include effects such as Dicke narrowing and the speed-dependence of the collisional width and shift in the line shape model, as was shown in previous cw-laser studies. In contrast to cw-laser based experiments, in this case the entire spectrum (˜ 250 wn) covering the whole P and R branches can be measured in 16 s with 417 MHz resolution, decreasing the acquisition time by orders of magnitude. The parallel acquisition allows collection of multiple lines simultaneously, removing the correlation of possible temperature and pressure drifts. While cw-systems are capable of measuring spectra with higher precision, this demonstration opens the door for fast

  5. Calibration of an astrophysical spectrograph below 1 m/s using a laser frequency comb

    NASA Astrophysics Data System (ADS)

    Phillips, David F.; Glenday, Alexander G.; Li, Chih-Hao; Cramer, Claire; Furesz, Gabor; Chang, Guoqing; Benedick, Andrew J.; Chen, Li-Jin; Kärtner, Franz X.; Korzennik, Sylvain; Sasselov, Dimitar; Szentgyorgyi, Andrew; Walsworth, Ronald L.

    2012-06-01

    We deployed two wavelength calibrators based on laser frequency combs ("astro-combs") at an astronomical telescope. One astro-comb operated over a 100 nm band in the deep red (∼ 800 nm) and a second operated over a 20 nm band in the blue (∼ 400 nm). We used these red and blue astro-combs to calibrate a high-resolution astrophysical spectrograph integrated with a 1.5 m telescope, and demonstrated calibration precision and stability suffici ent to enable detection of changes in stellar radial velocity < 1 m/s.

  6. Calibration of an astrophysical spectrograph below 1 m/s using a laser frequency comb.

    PubMed

    Phillips, David F; Glenday, Alexander G; Li, Chih-Hao; Cramer, Claire; Furesz, Gabor; Chang, Guoqing; Benedick, Andrew J; Chen, Li-Jin; Kärtner, Franz X; Korzennik, Sylvain; Sasselov, Dimitar; Szentgyorgyi, Andrew; Walsworth, Ronald L

    2012-06-18

    We deployed two wavelength calibrators based on laser frequency combs ("astro-combs") at an astronomical telescope. One astro-comb operated over a 100 nm band in the deep red (∼ 800 nm) and a second operated over a 20 nm band in the blue (∼ 400 nm). We used these red and blue astro-combs to calibrate a high-resolution astrophysical spectrograph integrated with a 1.5 m telescope, and demonstrated calibration precision and stability sufficient to enable detection of changes in stellar radial velocity < 1 m/s. PMID:22714437

  7. Static FBG strain sensor with high resolution and large dynamic range by dual-comb spectroscopy.

    PubMed

    Kuse, Naoya; Ozawa, Akira; Kobayashi, Yohei

    2013-05-01

    We demonstrate a fiber Bragg grating (FBG) strain sensor with optical frequency combs. To precisely characterize the optical response of the FBG when strain is applied, dual-comb spectroscopy is used. Highly sensitive dual-comb spectroscopy of the FBG enabled strain measurements with a resolution of 34 nε. The optical spectral bandwidth of the measurement exceeds 1 THz. Compared with conventional FBG strain sensor using a continuous-wave laser that requires rather slow frequency scanning with a limited range, the dynamic range and multiplexing capability are significantly improved by using broadband dual-comb spectroscopy. PMID:23669971

  8. Aluminum nitride as nonlinear optical material for on-chip frequency comb generation and frequency conversion

    NASA Astrophysics Data System (ADS)

    Jung, Hojoong; Tang, Hong X.

    2016-06-01

    A number of dielectric materials have been employed for on-chip frequency comb generation. Silicon based dielectrics such as silicon dioxide (SiO2) and silicon nitride (SiN) are particularly attractive comb materials due to their low optical loss and maturity in nanofabrication. They offer third-order Kerr nonlinearity (χ(3)), but little second-order Pockels (χ(2)) effect. Materials possessing both strong χ(2) and χ(3) are desired to enable selfreferenced frequency combs and active control of comb generation. In this review, we introduce another CMOS-compatible comb material, aluminum nitride (AlN),which offers both second and third order nonlinearities. A review of the advantages of AlN as linear and nonlinear optical material will be provided, and fabrication techniques of low loss AlN waveguides from the visible to infrared (IR) region will be discussed.We will then show the frequency comb generation including IR, red, and green combs in high-Q AlN micro-rings from single CW IR laser input via combination of Kerr and Pockels nonlinearity. Finally, the fast speed on-off switching of frequency comb using the Pockels effect of AlN will be shown,which further enriches the applications of the frequency comb.

  9. Kilohertz-Resolution Spectroscopy of Cold Atoms with an Optical Frequency Comb

    SciTech Connect

    Fortier, T. M.; Le Coq, Y.; Stalnaker, J. E.; Diddams, S. A.; Oates, C. W.; Hollberg, L.; Ortega, D.

    2006-10-20

    We have performed sub-Doppler spectroscopy on the narrow intercombination line of cold calcium atoms using the amplified output of a femtosecond laser frequency comb. Injection locking of a 657-nm diode laser with a femtosecond comb allows for two regimes of amplification, one in which many lines of the comb are amplified, and one where a single line is predominantly amplified. The output of the laser in both regimes was used to perform kilohertz-level spectroscopy. This experiment demonstrates the potential for high-resolution absolute-frequency spectroscopy over the entire spectrum of the frequency comb output using a single high-finesse optical reference cavity.

  10. A preliminary investigation of the potential mechanical sensitivity of vertical comb drives

    NASA Astrophysics Data System (ADS)

    Gallagher, E.; Moussa, W.

    2014-10-01

    This article describes a preliminary step taken in investigating the potential of vertical comb drives to be used as force-compensation mechanisms in interfacial force microscopes, by exploring the lower limit of the stiffness of the springs the comb drives can be fabricated with. The stiffness of their springs will affect the sensitivity of the microscope. Six vertical comb drives were fabricated for this study; the dimensions of their spring beams were chosen with the intention of giving them stiffnesses of three different orders of magnitude. During fabrication it was found that etching the tops of some of the teeth down to create the vertical offset between the combs can be done using only photoresist to mask the rest of the teeth. The stiffnesses of the fabricated springs were estimated by applying loads to them and measuring their resulting deflections. Weights were applied to the two comb drives with the stiffest springs. Voltages were also applied to them so as to determine the force-voltage relationship for their comb design. Since the other four comb drives had the same comb design, the stiffnesses of their springs could be estimated from the displacements of their movable combs when voltages were applied to them.

  11. Effect of a breather soliton in Kerr frequency combs on optical communication systems.

    PubMed

    Bao, Changjing; Liao, Peicheng; Zhang, Lin; Yan, Yan; Cao, Yinwen; Xie, Guodong; Mohajerin-Ariaei, Amirhossein; Li, Long; Ziyadi, Morteza; Almaiman, Ahmed; Kimerling, Lionel C; Michel, Jurgen; Willner, Alan E

    2016-04-15

    In this study, we numerically investigate the effect of Kerr-comb-generated breather soliton pulses on optical communication systems. The breather soliton pulse amplitude and spectrum envelope oscillate periodically in time. Simulations show that the spectrum of each comb line in the breather soliton state has multiple sub-teeth due to the periodic oscillation of the comb spectrum. In the simulation, the comb output is modulated with different formats. We find that the sub-teeth distort quadrature phase-shift-keyed signals but have less of an effect on on-off-keyed signals. PMID:27082339

  12. Damping effects of capacitive comb fingers on biomimetic MEMS directional microphone

    NASA Astrophysics Data System (ADS)

    Roth, John; Touse, Michael; Sinibaldi, Jose; Karunasiri, Gamani

    2011-03-01

    MEMS directional sound sensors that use two coupled wings moving in air are subjected to viscous damping. The amplitude of oscillation of the sensors is read out by measuring the capacitance of interdigitated comb fingers along the edges of the wings. In this presentation, effects of damping on MEMS sensors with and without comb fingers will be described. It was found that the sensors with comb fingers have a significantly larger damping indicating that the longer perimeter due to combs is responsible for the observed increase. However, the increase in damping reduces the quality factor which improves the response time of the device. This work is supported by NSF.

  13. Spectral linewidth preservation in parametric frequency combs seeded by dual pumps.

    PubMed

    Tong, Zhi; Wiberg, Andreas O J; Myslivets, Evgeny; Kuo, Bill P P; Alic, Nikola; Radic, Stojan

    2012-07-30

    We demonstrate new technique for generation of programmable-pitch, wideband frequency combs with low phase noise. The comb generation was achieved using cavity-less, multistage mixer driven by two tunable continuous-wave pump seeds. The approach relies on phase-correlated continuous-wave pumps in order to cancel spectral linewidth broadening inherent to parametric comb generation. Parametric combs with over 200-nm bandwidth were obtained and characterized with respect to phase noise scaling to demonstrate linewidth preservation over 100 generated tones. PMID:23038314

  14. Kilohertz-resolution spectroscopy of cold atoms with an optical frequency comb.

    PubMed

    Fortier, T M; Coq, Y Le; Stalnaker, J E; Ortega, D; Diddams, S A; Oates, C W; Hollberg, L

    2006-10-20

    We have performed sub-Doppler spectroscopy on the narrow intercombination line of cold calcium atoms using the amplified output of a femtosecond laser frequency comb. Injection locking of a 657-nm diode laser with a femtosecond comb allows for two regimes of amplification, one in which many lines of the comb are amplified, and one where a single line is predominantly amplified. The output of the laser in both regimes was used to perform kilohertz-level spectroscopy. This experiment demonstrates the potential for high-resolution absolute-frequency spectroscopy over the entire spectrum of the frequency comb output using a single high-finesse optical reference cavity. PMID:17155398

  15. The Tribolium castaneum ortholog of Sex combs reduced controls dorsal ridge development

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In insects, the boundary between the embryonic head and thorax is formed by the dorsal ridge, a fused structure composed of portions of the maxillary and labial segments. However, the mechanisms that promote development of this unusual structure remain a mystery. In Drosophila, mutations in the Hox ...

  16. Precision measurements and applications of femtosecond frequency combs

    NASA Astrophysics Data System (ADS)

    Jones, R. Jason

    2002-05-01

    The merging of femtosecond (fs) laser physics with the field of optical f requency metrology over recent years has had a profound impact on both di sciplines. Precision control of the broad frequency bandwidth from fs la sers has enabled new areas of exploration in ultrafast physics and revolu tionized optical frequency measurement and precision spectroscopy. Most recently, the transition frequency of the length standard at 514.7 nm,^ 127I2 P(13) 43-0 a3 has been measured in our lab with an improvement of more than 100 times in precision. Interesting molecular dynamics and s tructure are being explored using absolute frequency map of molecular tra nsitions over a large wavelength range. The iodine transition at 532 nm h as been used to establish an optical atomic clock with a fs comb providin g both an RF standard with stability comparable to the best atomic clocks and millions of optical frequencies across the visible and near IR spect rum, each stable to the Hz level. Work is presently underway to directly compare the iodine optical clocks at JILA with the Hg and Ca optical cloc ks currently being refined at NIST via a direct optical fiber link. A wi dely tunable single frequency laser in combination with a fs comb has bee n employed to realize an optical frequency synthesizer. Frequency combs of two independent ultrafast lasers have been coherently locked, enablin g several different avenues of application such as synthesis of arbitrary waveforms, coherent control of quantum systems, and coherent anti-Stokes Raman scattering microscopy. This talk will review these recent accompl ishments from our lab and discuss plans for further improving the control and precision of fs laser based measurements. te

  17. Multiple beam Fizeau interferometer with filtered frequency comb illumination

    NASA Astrophysics Data System (ADS)

    Schwider, J.

    2009-08-01

    Real wedge interferometers of the Fizeau-type do not allow for fringes in case of a spectral broadband source - or in short: for white light fringes. Here, the use of a suitable frequency comb source will help to overcome this limitation on the one hand and on the other will offer the capability for enhanced phase sensitivity in high precision measurements of surface deviations. Frequency combs can be produced either by using a pulse train from a fs-laser or by passive filtering of the light emitted by a broadband source as a superlum-diode or a fs-laser. The frequency comb produced by a common fs-laser is extremely fine, i.e., the frequency difference of consecutive peaks is very small or the distance of consecutive pulses of the pulse train might be of the order of 1 m. Therefore, the pulse train produced by passive filtering of a broadband source is better adapted to the needs of surface testing interferometers. White light fringes are either applied for the profiling of discontinuous surfaces and/or can serve as an indication for the correct choice of multiplication factors in superposition interferometry. During the last decennium it became more and more clear that spatially incoherent sources provide better measuring accuracy in surface measurements due to the reduced influence of dust diffraction patterns. The advantage of laser illumination can nevertheless be maintained if the laser light is made spatially incoherent through moving scatterers in the light path. Here, we will discuss the application of spatially incoherent broadband light frequency filtered through a Fabry-Perot filter. The main applications are in the following fields: (1) surface profiling applications using two-beam Fizeau interferometers, (2) selection of single cavities out of a series of interlaced cavities, and (3) sensitivity enhancement for multi-beam interferometers for planeness or sphericity measurements. Some of the discussed possibilities will be experimentally demonstrated.

  18. Entanglement of Atomic Qubits Using an Optical Frequency Comb

    SciTech Connect

    Hayes, D.; Matsukevich, D. N.; Maunz, P.; Hucul, D.; Quraishi, Q.; Olmschenk, S.; Campbell, W.; Mizrahi, J.; Senko, C.; Monroe, C.

    2010-04-09

    We demonstrate the use of an optical frequency comb to coherently control and entangle atomic qubits. A train of off-resonant ultrafast laser pulses is used to efficiently and coherently transfer population between electronic and vibrational states of trapped atomic ions and implement an entangling quantum logic gate with high fidelity. This technique can be extended to the high field regime where operations can be performed faster than the trap frequency. This general approach can be applied to more complex quantum systems, such as large collections of interacting atoms or molecules.

  19. Entanglement of atomic qubits using an optical frequency comb.

    PubMed

    Hayes, D; Matsukevich, D N; Maunz, P; Hucul, D; Quraishi, Q; Olmschenk, S; Campbell, W; Mizrahi, J; Senko, C; Monroe, C

    2010-04-01

    We demonstrate the use of an optical frequency comb to coherently control and entangle atomic qubits. A train of off-resonant ultrafast laser pulses is used to efficiently and coherently transfer population between electronic and vibrational states of trapped atomic ions and implement an entangling quantum logic gate with high fidelity. This technique can be extended to the high field regime where operations can be performed faster than the trap frequency. This general approach can be applied to more complex quantum systems, such as large collections of interacting atoms or molecules. PMID:20481925

  20. Microwave photonic comb filter with ultra-fast tunability.

    PubMed

    Jiang, H Y; Yan, L S; Pan, Y; Pan, W; Luo, B; Zou, X H; Eggleton, B J

    2015-11-01

    A microwave comb filter with ultra-fast tunability is proposed based on the fundamental delay-line microwave photonic filter. The central frequency of the passband or stopband in such a filter can be rapidly adjusted, along with the independent tunability of the free spectral range (FSR). Experimental results show that the central frequency of the transfer function is electronically tuned with a frequency difference of half of the FSR at a speed of <100  ps. Such high-speed tunability is vital for high-speed microwave switching, frequency hopping, cognitive radio, and next-generation radar systems. PMID:26512477

  1. Full Multipartite Entanglement of Frequency-Comb Gaussian States

    NASA Astrophysics Data System (ADS)

    Gerke, S.; Sperling, J.; Vogel, W.; Cai, Y.; Roslund, J.; Treps, N.; Fabre, C.

    2015-02-01

    An analysis is conducted of the multipartite entanglement for Gaussian states generated by the parametric down-conversion of a femtosecond frequency comb. Using a recently introduced method for constructing optimal entanglement criteria, a family of tests is formulated for mode decompositions that extends beyond the traditional bipartition analyses. A numerical optimization over this family is performed to achieve maximal significance of entanglement verification. For experimentally prepared 4-, 6-, and 10-mode states, full entanglement is certified for all of the 14, 202, and 115 974 possible nontrivial partitions, respectively.

  2. Frequency combs with weakly lasing exciton-polariton condensates.

    PubMed

    Rayanov, K; Altshuler, B L; Rubo, Y G; Flach, S

    2015-05-15

    We predict the spontaneous modulated emission from a pair of exciton-polariton condensates due to coherent (Josephson) and dissipative coupling. We show that strong polariton-polariton interaction generates complex dynamics in the weak-lasing domain way beyond Hopf bifurcations. As a result, the exciton-polariton condensates exhibit self-induced oscillations and emit an equidistant frequency comb light spectrum. A plethora of possible emission spectra with asymmetric peak distributions appears due to spontaneously broken time-reversal symmetry. The lasing dynamics is affected by the shot noise arising from the influx of polaritons. That results in a complex inhomogeneous line broadening. PMID:26024173

  3. Frequency stabilized optical comb source with high finesse intracavity etalon

    NASA Astrophysics Data System (ADS)

    Ozdur, Ibrahim; Ozharar, Sarper; Akbulut, Mehmetcan; Mandridis, Dimitrios; Quinlan, Franklyn; Delfyett, Peter J.

    2009-05-01

    Mode-locked lasers have applications in signal processing and communications such as analog to digital conversion, arbitrary waveform generation and wavelength division multiplexing. For such applications low noise and phase coherent frequency stabilized optical combs are needed. In this work we report a low noise, Pound-Drever Hall frequency stabilized, semiconductor mode-locked laser at 10.287GHz centered at 1550nm with 1000-Finesse sealed, ultralow insertion loss intracavity etalon. The output optical power of the mode locked laser is ~5mW.

  4. Curcumin reduces injury progression in a rat comb burn model.

    PubMed

    Singer, Adam J; Taira, Breena R; Lin, Fubao; Lim, Taeho; Anderson, Ryon; McClain, Steve A; Clark, Richard A F

    2011-01-01

    The oriental spice curcumin has anti-inflammatory and antioxidant effects. When given orally before injury, curcumin reduces burn progression in a rat comb burn model. The authors hypothesized that intravenous administration of curcumin after injury would reduce burn progression and that its effects are mediated through iron chelation. Two comb burns were created on the dorsum of Sprague-Dawley rats (weight, 300 g) using a brass comb with four rectangular prongs preheated in boiling water and applied for 30 seconds resulting in four rectangular 10 × 20 mm full-thickness burns separated by three 5 × 20 mm unburned interspaces (zone of ischemia). Animals were randomized to receive one of four doses of crude curcumin or one of six doses of purified curcumin intravenously 1 and 24 hours after injury. Another set of animals were randomized to deferoxamine or control vehicle. Wounds were observed at 7 days after injury for visual evidence of necrosis in the unburned interspaces. Full-thickness biopsies from the interspaces were evaluated with Hematoxylin and Eosin staining 7 days after injury for evidence of necrosis. The percentage of unburned interspaces undergoing necrosis at 1 week by purified curcumin doses was 0 μg/kg, 74%; 0.3 μg/kg, 58%; 1 μg/kg, 53%; 3 μg/kg, 37%; 10 μg/kg, 63%; 30 μg/kg, 53%; and 100 μg/kg, 26%. The differences among the groups were significant (P = .03). When compared with controls, the 1 and 3 μg/kg curcumin treatment groups had significantly less progression of interspaces to necrosis (P = .04 and .002) as did the 30 and 100 μg/kg treatment groups (P = .03 and <.001). Deferoxamine did not reduce burn progression. When administered intravenously 1 and 24 hours after injury, both crude and purified curcumin reduce the percentage of unburned interspaces that undergo necrosis in a rat hot comb burn model. The effects of purified curcumin appear to be bimodal, suggesting more than one mechanism of action. The effects of curcumin do not

  5. Parametric seeding of a microresonator optical frequency comb.

    PubMed

    Papp, Scott B; Del'Haye, Pascal; Diddams, Scott A

    2013-07-29

    We have investigated parametric seeding of a microresonator frequency comb (microcomb) by way of a pump laser with two electro-optic-modulation sidebands. We show that the pump-sideband spacing is precisely replicated throughout the microcomb's optical spectrum, and we demonstrate a record absolute line-spacing stability for microcombs of 1.6 × 10(-13) at 1 s. The spectrum of a microcomb is complex, and often non-equidistant subcombs are observed. Our results demonstrate that parametric seeding can not only control the subcombs, but can lead to the generation of a strictly equidistant microcomb spectrum. PMID:23938634

  6. Hair combing to collect organic gunshot residues (OGSR).

    PubMed

    MacCrehan, William A; Layman, Malinda J; Secl, Janelle D

    2003-08-12

    A protocol is presented for the collection and analysis of gunshot residues (GSR) from hair. A fine-toothed comb is used for collection of the residues. A small zip-closure bag serves as a container for both sample storage and extraction of the characteristic organic powder additives. The success of this residue recovery approach was tested on simulated shooters and victims using mannequin-supported human wig hair as well as on human shooters. Residues were collected from four weapons: a revolver and semi-automatic pistol, rifle and shotgun. One characteristic additive, nitroglycerin, was detected by capillary electrophoresis (CE) in the majority of the collection experiments. PMID:12927420

  7. Dual-frequency comb generation with differing GHz repetition rates by parallel Fabry–Perot cavity filtering of a single broadband frequency comb source

    NASA Astrophysics Data System (ADS)

    Mildner, Jutta; Meiners-Hagen, Karl; Pollinger, Florian

    2016-07-01

    We present a dual-comb-generator based on a coupled Fabry–Perot filtering cavity doublet and a single seed laser source. By filtering a commercial erbium-doped fiber-based optical frequency comb with CEO-stabilisation and 250 MHz repetition rate, two broadband coherent combs of different repetition rates in the GHz range are generated. The filtering doublet consists of two Fabry–Perot cavities with a tunable spacing and Pound–Drever–Hall stabilisation scheme. As a prerequisite for the development of such a filtering unit, we present a method to determine the actual free spectral range and transmission bandwidth of a Fabry–Perot cavity in situ. The transmitted beat signal of two diode lasers is measured as a function of their tunable frequency difference. Finally, the filtering performance and resulting beat signals of the heterodyned combs are discussed as well as the optimisation measures of the whole system.

  8. Astronomical optical frequency comb generation and test in a fiber-fed MUSE spectrograph

    NASA Astrophysics Data System (ADS)

    Chavez Boggio, J. M.; Fremberg, T.; Moralejo, B.; Rutowska, M.; Hernandez, E.; Zajnulina, M.; Kelz, A.; Bodenmüller, D.; Sandin, C.; Wysmolek, M.; Sayinc, H.; Neumann, J.; Haynes, R.; Roth, M. M.

    2014-07-01

    We here report on recent progress on astronomical optical frequency comb generation at innoFSPEC-Potsdam and present preliminary test results using the fiber-fed Multi Unit Spectroscopic Explorer (MUSE) spectrograph. The frequency comb is generated by propagating two free-running lasers at 1554.3 and 1558.9 nm through two dispersionoptimized nonlinear fibers. The generated comb is centered at 1590 nm and comprises more than one hundred lines with an optical-signal-to-noise ratio larger than 30 dB. A nonlinear crystal is used to frequency double the whole comb spectrum, which is efficiently converted into the 800 nm spectral band. We evaluate first the wavelength stability using an optical spectrum analyzer with 0.02 nm resolution and wavelength grid of 0.01 nm. After confirming the stability within 0.01 nm, we compare the spectra of the astro-comb and the Ne and Hg calibration lamps: the astro-comb exhibits a much larger number of lines than lamp calibration sources. A series of preliminary tests using a fiber-fed MUSE spectrograph are subsequently carried out with the main goal of assessing the equidistancy of the comb lines. Using a P3d data reduction software we determine the centroid and the width of each comb line (for each of the 400 fibers feeding the spectrograph): equidistancy is confirmed with an absolute accuracy of 0.4 pm.

  9. Noise dynamics of a prism-based Cr:forsterite laser frequency comb

    NASA Astrophysics Data System (ADS)

    Wu, Shun; Washburn, Brian; Corwin, Kristan; Tillman, Karl

    2010-03-01

    Mode-locked Cr:forsterite lasers are of significant interest as infrared frequency combs due to their ability to generate stable high repetition rate femtosecond pulses. However, self-referenced Cr:forsterite frequency combs tend to exhibit wide carrier-envelope offset frequency (f0) linewidths. These large f0 linewidths can be attributed to significant frequency noise across the comb's spectral bandwidth and result in broad comb teeth. We have stabilized a prism-based Cr:forsterite frequency comb and observed narrowing of the f0 linewidth from ˜1 MHz down to <100 kHz when a knife edge is inserted into the intracavity beam as a spectral filter. This can also be further reduced after phase-locking the comb to a low-phase noise rf oscillator. Thus, the introduction of an intracavity knife edge significantly reduces the frequency noise of the system and enables more effective stabilization of the entire comb. A theoretical model has been used to investigate the noise dynamics of the phase-stabilized comb system. It includes: the pump laser power (P), the frequency dependence of the f0 response to pump power changes ((df0/dP)(ν)), and the frequency dependence of the femtosecond laser's relative intensity noise, RIN(ν). Supported by AFOSR FA9950-05-1-0304 and NSF ECS-0449295

  10. High resolution atomic coherent control via spectral phase manipulation of an optical frequency comb.

    PubMed

    Stowe, Matthew C; Cruz, Flavio C; Marian, Adela; Ye, Jun

    2006-04-21

    We demonstrate high resolution coherent control of cold atomic rubidium utilizing spectral phase manipulation of a femtosecond optical frequency comb. Transient coherent accumulation is directly manifested by the enhancement of signal amplitude and spectral resolution via the pulse number. The combination of frequency comb technology and spectral phase manipulation enables coherent control techniques to enter a new regime with natural linewidth resolution. PMID:16712153

  11. High Resolution Atomic Coherent Control via Spectral Phase Manipulation of an Optical Frequency Comb

    SciTech Connect

    Stowe, Matthew C.; Cruz, Flavio C.; Marian, Adela; Ye Jun

    2006-04-21

    We demonstrate high resolution coherent control of cold atomic rubidium utilizing spectral phase manipulation of a femtosecond optical frequency comb. Transient coherent accumulation is directly manifested by the enhancement of signal amplitude and spectral resolution via the pulse number. The combination of frequency comb technology and spectral phase manipulation enables coherent control techniques to enter a new regime with natural linewidth resolution.

  12. Optimally Coherent Kerr Combs Generated with Crystalline Whispering Gallery Mode Resonators for Ultrahigh Capacity Fiber Communications

    NASA Astrophysics Data System (ADS)

    Pfeifle, Joerg; Coillet, Aurélien; Henriet, Rémi; Saleh, Khaldoun; Schindler, Philipp; Weimann, Claudius; Freude, Wolfgang; Balakireva, Irina V.; Larger, Laurent; Koos, Christian; Chembo, Yanne K.

    2015-03-01

    Optical Kerr frequency combs are known to be effective coherent multiwavelength sources for ultrahigh capacity fiber communications. These combs are the frequency-domain counterparts of a wide variety of spatiotemporal dissipative structures, such as cavity solitons, chaos, or Turing patterns (rolls). In this Letter, we demonstrate that Turing patterns, which correspond to the so-called primary combs in the spectral domain, are optimally coherent in the sense that for the same pump power they provide the most robust carriers for coherent data transmission in fiber communications using advanced modulation formats. Our model is based on a stochastic Lugiato-Lefever equation which accounts for laser pump frequency jitter and amplified spontaneous emission noise induced by the erbium-doped fiber amplifier. Using crystalline whispering-gallery-mode resonators with quality factor Q ˜109 for the comb generation, we show that when the noise is accounted for, the coherence of a primary comb is significantly higher than the coherence of their solitonic or chaotic counterparts for the same pump power. In order to confirm this theoretical finding, we perform an optical fiber transmission experiment using advanced modulation formats, and we show that the coherence of the primary comb is high enough to enable data transmission of up to 144 Gbit /s per comb line, the highest value achieved with a Kerr comb so far. This performance evidences that compact crystalline photonic systems have the potential to play a key role in a new generation of coherent fiber communication networks, alongside fully integrated systems.

  13. Frequency-divide-and-conquer approach to creating frequency combs in the infrared

    NASA Astrophysics Data System (ADS)

    Vodopyanov, K.; Leindecker, N.; Marandi, A.; Byer, R.; Pervak, V.

    2010-10-01

    The technique of optical Frequency Combs - a broadband series of some million sharp equidistant phase-locked frequency spikes from mode-locked femtosecond lasers - has revolutionized optical frequency metrology and led to creation of optical atomic clocks. Also, frequency combs opened new capabilities in molecular spectroscopy since they provide a unique combination of large wavelength coverage, high spectral resolution, and the ability of parallel spectral data acquisition. Practical comb sources based on Ti:sapphire, Yb- and Er- fiber lasers, are limited to the near-IR spectral region, λ< 2 μm, while to take the full advantage of frequency combs for molecular spectroscopy, one would need operation at longer ( > 2.5 μm) wavelengths, that is in the region of fundamental rotational-vibrational absorption bands. Here we implement a new approach for creating broadband mid-infrared frequency combs based on a subharmonic optical parametric oscillator (OPO). The source conveniently down converts the frequency comb of an erbium fiber laser with a center wavelength of 1560nm and produces a 2/3-octaves-wide frequency comb centered at λ = 3.1 μm with 40% quantum efficiency. The frequency comb is phase-locked to the pump laser and has other remarkable coherence properties which we studied by interfering the outputs of two identical OPOs pumped by the same laser.

  14. Sub-Lethal Effects of Pesticide Residues in Brood Comb on Worker Honey Bee (Apis mellifera) Development and Longevity

    PubMed Central

    Wu, Judy Y.; Anelli, Carol M.; Sheppard, Walter S.

    2011-01-01

    Background Numerous surveys reveal high levels of pesticide residue contamination in honey bee comb. We conducted studies to examine possible direct and indirect effects of pesticide exposure from contaminated brood comb on developing worker bees and adult worker lifespan. Methodology/Principal Findings Worker bees were reared in brood comb containing high levels of known pesticide residues (treatment) or in relatively uncontaminated brood comb (control). Delayed development was observed in bees reared in treatment combs containing high levels of pesticides particularly in the early stages (day 4 and 8) of worker bee development. Adult longevity was reduced by 4 days in bees exposed to pesticide residues in contaminated brood comb during development. Pesticide residue migration from comb containing high pesticide residues caused contamination of control comb after multiple brood cycles and provided insight on how quickly residues move through wax. Higher brood mortality and delayed adult emergence occurred after multiple brood cycles in contaminated control combs. In contrast, survivability increased in bees reared in treatment comb after multiple brood cycles when pesticide residues had been reduced in treatment combs due to residue migration into uncontaminated control combs, supporting comb replacement efforts. Chemical analysis after the experiment confirmed the migration of pesticide residues from treatment combs into previously uncontaminated control comb. Conclusions/Significance This study is the first to demonstrate sub-lethal effects on worker honey bees from pesticide residue exposure from contaminated brood comb. Sub-lethal effects, including delayed larval development and adult emergence or shortened adult longevity, can have indirect effects on the colony such as premature shifts in hive roles and foraging activity. In addition, longer development time for bees may provide a reproductive advantage for parasitic Varroa destructor mites. The impact of

  15. Photothermally driven fast responding photo-actuators fabricated with comb-type hydrogels and magnetite nanoparticles

    PubMed Central

    Lee, Eunsu; Kim, Dowan; Kim, Haneul; Yoon, Jinhwan

    2015-01-01

    To overcome the slow kinetics of the volume phase transition of stimuli-responsive hydrogels as platforms for soft actuators, thermally responsive comb-type hydrogels were prepared using synthesized poly(N-isopropylacrylamide) macromonomers bearing graft chains. Fast responding light-responsive hydrogels were fabricated by combining a comb-type hydrogel matrix with photothermal magnetite nanoparticles (MNP). The MNPs dispersed in the matrix provide heat to stimulate the volume change of the hydrogel matrix by converting absorbed visible light to thermal energy. In this process, the comb-type hydrogel matrix exhibited a rapid response due to the free, mobile grafted chains. The comb-type hydrogel exhibited significantly enhanced light-induced volume shrinkage and rapid recovery. The comb-type hydrogels containing MNP were successfully used to fabricate a bilayer-type photo-actuator with fast bending motion. PMID:26459918

  16. Phase-locking transition in Raman combs generated with whispering gallery mode resonators.

    PubMed

    Lin, Guoping; Chembo, Yanne K

    2016-08-15

    We investigate the mechanisms leading to phase locking in Raman optical frequency combs generated with ultrahigh Q crystalline whispering gallery mode disk resonators. We show that several regimes can be triggered depending on the pumping conditions, such as single-frequency Raman lasing, multimode operation involving more than one family of cavity eigenmodes, and Kerr-assisted Raman frequency comb generation. The phase locking and coherence of the combs are experimentally monitored through the measurement of beat signal spectra. These phase-locked combs, which feature high coherence and wide spectral spans, are obtained with pump powers in the range of a few tens of mW. In particular, Raman frequency combs with multiple free-spectral range spacings are reported, and the measured beat signal in the microwave domain features a 3 dB linewidth smaller than 50 Hz, thereby indicating phase locking. PMID:27519071

  17. Fabrication of comb interdigitated electrodes array (IDA) for a microbead-based electrochemical assay system.

    PubMed

    Kim, Sang Kyung; Hesketh, Peter J; Li, Changming; Thomas, Jennifer H; Halsall, H Brian; Heineman, William R

    2004-11-01

    This research is directed towards developing a more sensitive and rapid electrochemical sensor for enzyme labeled immunoassays by coupling redox cycling at interdigitated electrode arrays (IDA) with the enzyme label beta-galactosidase. Coplanar and comb IDA electrodes with a 2.4 microm gap were fabricated and their redox cycling currents were measured. ANSYS was used to model steady state currents for electrodes with different geometries. Comb IDA electrodes enhanced the signal about three times more than the coplanar IDAs, which agreed with the results of the simulation. Magnetic microbead-based enzyme assay, as a typical example of biochemical detection, was done using the comb and coplanar IDAs. The enzymes could be placed close to the sensing electrodes (approximately 10 microm for the comb IDAs) and detection took less than 1 min with a limit of detection of 70 amol of beta-galactosidase. We conclude that faster and more sensitive assays can be achieved with the comb IDA. PMID:15522606

  18. High-performance, vibration-immune, fiber-laser frequency comb.

    PubMed

    Baumann, Esther; Giorgetta, Fabrizio R; Nicholson, Jeffrey W; Swann, William C; Coddington, Ian; Newbury, Nathan R

    2009-03-01

    We demonstrate an environmentally robust optical frequency comb based on a polarization-maintaining, all-fiber, figure-eight laser. The comb is phase locked to a cavity-stabilized cw laser by use of an intracavity electro-optic phase modulator yielding 1.6 MHz feedback bandwidth. This high bandwidth provides close to shot-noise-limited residual phase noise between the comb and cw reference laser of -94 dBc/Hz from 20 Hz to 200 kHz and an integrated in-loop phase noise of 32 mrad from 1 Hz to 1 MHz. Moreover, the comb remains phase locked under significant mechanical vibrations of over 1 g. This level of environmental robustness is an important step toward a fieldable fiber frequency comb. PMID:19252577

  19. Characterization of a DFG comb showing quadratic scaling of the phase noise with frequency.

    PubMed

    Puppe, Thomas; Sell, Alexander; Kliese, Russell; Hoghooghi, Nazanin; Zach, Armin; Kaenders, Wilhelm

    2016-04-15

    We characterize an Er:fiber laser frequency comb that is passively carrier envelope phase-stabilized via difference frequency generation at a wavelength of 1550 nm. A generic method to measure the comb linewidth at different wavelengths is demonstrated. By transferring the properties of a comb line to a cw external cavity diode laser, the phase noise is subsequently measured by tracking the delayed self-heterodyne beat note. This relatively simple characterization method is suitable for a broad range of optical frequencies. Here, it is used to characterize our difference frequency generation (DFG) comb over nearly an optical octave. With repetition-rate stabilization, a radiofrequency reference oscillator limited linewidth is achieved. A lock to an optical reference shows out-of-loop linewidths of the comb at the hertz level. The phase noise measurements are in excellent agreement with the elastic tape model with a fix point at zero frequency. PMID:27082368

  20. Octave-wide frequency comb centered at 4 μm based on a subharmonic OPO with Hz-level relative comb linewidth

    NASA Astrophysics Data System (ADS)

    Smolski, V. O.; Xu, J.; Schunemann, P. G.; Vodopyanov, K. L.

    2016-03-01

    We study coherence properties of a more-than-octave-wide (2.6-7.5 μm) mid-IR frequency comb based on a 2-μm Tmfiber- laser-pumped degenerate (subharmonic) optical parametric oscillator (OPO) that uses orientation-patterned gallium arsenide (OP-GaAs) as gain element. By varying intracavity dispersion, we observed a 'phase' transition from a singlecomb state (at exactly OPO degeneracy) to a two-comb state (near-degenerate operation), characterized by two spectrally overlapping combs (signal and idler) with distinct carrier-envelope offset frequencies. We achieve this by generating a supercontinuum (SC) from the mode-locked Tm laser that spans most of the near-IR range, and observing RF beats between the SC and parasitic sum-frequency light (pump + OPO) that also falls into the near-IR. We found RF linewidth to be <15 Hz (a resolution of our spectrum analyzer), which proves that coherence of the pump laser comb is preserved to a high degree in a subharmonic OPO. Transition to a two-comb state was characterized by a symmetric splitting of the RF peak. Low pump threshold (down to 7 mW), high (73 mW) average power and high (up to 90%) pump depletion make this comb source very attractive for numerous applications including trace molecular detection and chemical sensing with massively parallel spectral data acquisition.

  1. When Sex Is Painful

    MedlinePlus

    ... AQ FREQUENTLY ASKED QUESTIONS GYNECOLOGIC PROBLEMS FAQ020 When Sex Is Painful • How common is painful sex? • What causes pain during sex? • Where is pain during sex felt? • When should ...

  2. pH-dependent specific binding and combing of DNA.

    PubMed Central

    Allemand, J F; Bensimon, D; Jullien, L; Bensimon, A; Croquette, V

    1997-01-01

    Recent developments in the rapid sequencing, mapping, and analysis of DNA rely on the specific binding of DNA to specially treated surfaces. We show here that specific binding of DNA via its unmodified extremities can be achieved on a great variety of surfaces by a judicious choice of the pH. On hydrophobic surfaces the best binding efficiency is reached at a pH of approximately 5.5. At that pH a approximately 40-kbp DNA is 10 times more likely to bind by an extremity than by a midsegment. A model is proposed to account for the differential adsorption of the molecule extremities and midsection as a function of pH. The pH-dependent specific binding can be used to align anchored DNA molecules by a receding meniscus, a process called molecular combing. The resulting properties of the combed molecules will be discussed. Images FIGURE 1 FIGURE 2 FIGURE 3 FIGURE 6 FIGURE 7 PMID:9336201

  3. Development of femtosecond optical frequency comb laser tracker

    NASA Astrophysics Data System (ADS)

    Yang, Ju-qing; Zhou, Wei-hu; Dong, Deng-feng; Zhang, Zi-li; Lao, Da-bao; Ji, Rong-yi; Wang, Da-yong

    2016-01-01

    A new type femtosecond laser tracker is one high precision measurement instrument with urgent need in science research region and industrial manufacture field. This paper focuses on the operational principle and the structure development of the femtosecond laser tracer, and the method of error compensation as well. The system modules were studied and constructed. The femtosecond frequency comb module was firstly analyzed and developed. The femtosecond laser frequency comb performed perfectly high precise distance measurement for laser tracker. The experimental result showed that the stability of repetition rate reached 3.0×10-12@1s and the stability of carrier envelop offset reached 1.0×10-10@1s. The initial experiment showed that measurement error was less than 1ppm. Later the error compensation module was introduced, and the optoelectronic aiming and tracking control module was built. The actual test result showed that the stability of miss distance was better than 2.0 μm, the tracking speed could reach 2m/s.

  4. A Fine-Tooth Comb to Measure the Accelerating Universe

    NASA Astrophysics Data System (ADS)

    2008-09-01

    Astronomical instruments needed to answer crucial questions, such as the search for Earth-like planets or the way the Universe expands, have come a step closer with the first demonstration at the telescope of a new calibration system for precise spectrographs. The method uses a Nobel Prize-winning technology called a 'laser frequency comb', and is published in this week's issue of Science. Uncovering the disc ESO PR Photo 26a/08 A Laser Comb for Astronomy "It looks as if we are on the way to fulfil one of astronomers' dreams," says team member Theodor Hänsch, director at the Max Planck Institute for Quantum Optics (MPQ) in Germany. Hänsch, together with John Hall, was awarded the 2005 Nobel Prize in Physics for work including the frequency comb technique. Astronomers use instruments called spectrographs to spread the light from celestial objects into its component colours, or frequencies, in the same way water droplets create a rainbow from sunlight. They can then measure the velocities of stars, galaxies and quasars, search for planets around other stars, or study the expansion of the Universe. A spectrograph must be accurately calibrated so that the frequencies of light can be correctly measured. This is similar to how we need accurate rulers to measure lengths correctly. In the present case, a laser provides a sort of ruler, for measuring colours rather than distances, with an extremely accurate and fine grid. New, extremely precise spectrographs will be needed in experiments planned for the future European Extremely Large Telescope (E-ELT), which is being designed by ESO, the European Southern Observatory. These new spectrographs will need to be calibrated with even more accurate 'rulers'. In fact, they must be accurate to about one part in 30 billions - a feat equivalent to measuring the circumference of the Earth to about a millimetre! "We'll need something beyond what current technology can offer, and that's where the laser frequency comb comes in. It is

  5. Comb-referenced laser distance interferometer for industrial nanotechnology

    PubMed Central

    Jang, Yoon-Soo; Wang, Guochao; Hyun, Sangwon; Kang, Hyun Jay; Chun, Byung Jae; Kim, Young-Jin; Kim, Seung-Woo

    2016-01-01

    A prototype laser distance interferometer is demonstrated by incorporating the frequency comb of a femtosecond laser for mass-production of optoelectronic devices such as flat panel displays and solar cell devices. This comb-referenced interferometer uses four different wavelengths simultaneously to enable absolute distance measurement with the capability of comprehensive evaluation of the measurement stability and uncertainty. The measurement result reveals that the stability reaches 3.4 nm for a 3.8 m distance at 1.0 s averaging, which further reduces to 0.57 nm at 100 s averaging with a fractional stability of 1.5 × 10−10. The uncertainty is estimated to be in a 10−8 level when distance is measured in air due to the inevitable ambiguity in estimating the refractive index, but it can be enhanced to a 10−10 level in vacuum. PMID:27558016

  6. A single comb laser source for short reach WDM interconnects

    NASA Astrophysics Data System (ADS)

    Wojcik, Gregory L.; Yin, Dongliang; Kovsh, Alexey R.; Gubenko, Alexey E.; Krestnikov, Igor L.; Mikhrin, Sergey S.; Livshits, Daniil A.; Fattal, David A.; Fiorentino, Marco; Beausoleil, Raymond G.

    2009-02-01

    High-channel-count WDM will eventually be used for short reach optical interconnects since it maximizes link bandwidth and efficiency. An impediment to adoption is the fact that each WDM wavelength currently requires its own DFB laser. The alternative is a single, multi-wavelength laser, but noise, size and/or expense make existing options impractical. In contrast, a new low-noise, diode comb laser based on InAs/GaAs quantum dots provides a practical and timely alternative, albeit in the O-band. Samples are being evaluated in short reach WDM development systems. Tests show this type of Fabry-Perot laser permits >10 Gb/s error-free modulation of 10 to over 50 separate channels, as well as potential for 1.25 Gb/s direct modulation. The paper describes comb laser requirements, noise measurements for external and direct modulation, O-band issues, transmitter photonic circuitry and components, future CMP applications, and optical couplers that may help drive down packaging costs to below a dollar.

  7. Harnessing high-dimensional hyperentanglement through a biphoton frequency comb

    NASA Astrophysics Data System (ADS)

    Xie, Zhenda; Zhong, Tian; Shrestha, Sajan; Xu, Xinan; Liang, Junlin; Gong, Yan-Xiao; Bienfang, Joshua C.; Restelli, Alessandro; Shapiro, Jeffrey H.; Wong, Franco N. C.; Wei Wong, Chee

    2015-08-01

    Quantum entanglement is a fundamental resource for secure information processing and communications, and hyperentanglement or high-dimensional entanglement has been separately proposed for its high data capacity and error resilience. The continuous-variable nature of the energy-time entanglement makes it an ideal candidate for efficient high-dimensional coding with minimal limitations. Here, we demonstrate the first simultaneous high-dimensional hyperentanglement using a biphoton frequency comb to harness the full potential in both the energy and time domain. Long-postulated Hong-Ou-Mandel quantum revival is exhibited, with up to 19 time-bins and 96.5% visibilities. We further witness the high-dimensional energy-time entanglement through Franson revivals, observed periodically at integer time-bins, with 97.8% visibility. This qudit state is observed to simultaneously violate the generalized Bell inequality by up to 10.95 standard deviations while observing recurrent Clauser-Horne-Shimony-Holt S-parameters up to 2.76. Our biphoton frequency comb provides a platform for photon-efficient quantum communications towards the ultimate channel capacity through energy-time-polarization high-dimensional encoding.

  8. Comb-referenced laser distance interferometer for industrial nanotechnology.

    PubMed

    Jang, Yoon-Soo; Wang, Guochao; Hyun, Sangwon; Kang, Hyun Jay; Chun, Byung Jae; Kim, Young-Jin; Kim, Seung-Woo

    2016-01-01

    A prototype laser distance interferometer is demonstrated by incorporating the frequency comb of a femtosecond laser for mass-production of optoelectronic devices such as flat panel displays and solar cell devices. This comb-referenced interferometer uses four different wavelengths simultaneously to enable absolute distance measurement with the capability of comprehensive evaluation of the measurement stability and uncertainty. The measurement result reveals that the stability reaches 3.4 nm for a 3.8 m distance at 1.0 s averaging, which further reduces to 0.57 nm at 100 s averaging with a fractional stability of 1.5 × 10(-10). The uncertainty is estimated to be in a 10(-8) level when distance is measured in air due to the inevitable ambiguity in estimating the refractive index, but it can be enhanced to a 10(-10) level in vacuum. PMID:27558016

  9. Lévy processes on a generalized fractal comb

    NASA Astrophysics Data System (ADS)

    Sandev, Trifce; Iomin, Alexander; Méndez, Vicenç

    2016-09-01

    Comb geometry, constituted of a backbone and fingers, is one of the most simple paradigm of a two-dimensional structure, where anomalous diffusion can be realized in the framework of Markov processes. However, the intrinsic properties of the structure can destroy this Markovian transport. These effects can be described by the memory and spatial kernels. In particular, the fractal structure of the fingers, which is controlled by the spatial kernel in both the real and the Fourier spaces, leads to the Lévy processes (Lévy flights) and superdiffusion. This generalization of the fractional diffusion is described by the Riesz space fractional derivative. In the framework of this generalized fractal comb model, Lévy processes are considered, and exact solutions for the probability distribution functions are obtained in terms of the Fox H-function for a variety of the memory kernels, and the rate of the superdiffusive spreading is studied by calculating the fractional moments. For a special form of the memory kernels, we also observed a competition between long rests and long jumps. Finally, we considered the fractal structure of the fingers controlled by a Weierstrass function, which leads to the power-law kernel in the Fourier space. This is a special case, when the second moment exists for superdiffusion in this competition between long rests and long jumps.

  10. Flexible radio-frequency photonics: Optoelectronic frequency combs and integrated pulse shaping

    NASA Astrophysics Data System (ADS)

    Metcalf, Andrew J.

    Microwave photonics is a discipline which leverages optoelectronics to enhance the generation, transport, and processing of high-frequency electrical signals. At the heart of many emerging techniques is the optical frequency comb. A comb is a lightwave source whose spectrum is made up of discrete equally spaced spectral components that share a fixed phase relationship. These discrete coherent oscillators --known as comb lines-- collectively form a Fourier basis that describe a periodic optical waveform. Within the last two decades frequency-stabilized broadband combs produced from mode-locked lasers have led to revolutionary advancements in precision optical frequency synthesis and metrology. Meanwhile, Fourier-transform optical pulse shaping, which provides a means to control a comb's Fourier basis in both amplitude and phase, has emerged as an integral tool in optical communications, broadband waveform generation, and microwave photonic filtering. However, traditional comb and pulse shaping architectures are often plagued by complex and bulky setups, rendering robust and cost effective implementation outside of the laboratory a challenge. In addition, traditional comb sources based on short-pulse lasers do not possess qualities which are ideally suited for this new application regime. Motivated by the shortcomings in current architectures, and empowered by recent advancements in optoelectronic technology, this dissertation focuses on developing novel and robust schemes in optical frequency comb generation and line-by-line pulse shaping. Our results include: the invention and low-noise characterization of a broadband flat-top comb source; the realization of an optoelectronic-based time cloak; and finally, the development of an integrated pulse shaper, which we use in conjunction with our flat-top comb source to demonstrate a rapidly reconfigurable microwave photonic filter.

  11. Molecular combing compared to Southern blot for measuring D4Z4 contractions in FSHD.

    PubMed

    Vasale, Jessica; Boyar, Fatih; Jocson, Michael; Sulcova, Vladimira; Chan, Patricia; Liaquat, Khalida; Hoffman, Carol; Meservey, Marc; Chang, Isabell; Tsao, David; Hensley, Kerri; Liu, Yan; Owen, Renius; Braastad, Corey; Sun, Weimin; Walrafen, Pierre; Komatsu, Jun; Wang, Jia-Chi; Bensimon, Aaron; Anguiano, Arturo; Jaremko, Malgorzata; Wang, Zhenyuan; Batish, Sat; Strom, Charles; Higgins, Joseph

    2015-12-01

    We compare molecular combing to Southern blot in the analysis of the facioscapulohumeral muscular dystrophy type 1 locus (FSHD1) on chromosome 4q35-qter (chr 4q) in genomic DNA specimens sent to a clinical laboratory for FSHD testing. A de-identified set of 87 genomic DNA specimens determined by Southern blot as normal (n = 71), abnormal with D4Z4 macrosatellite repeat array contractions (n = 7), indeterminate (n = 6), borderline (n = 2), or mosaic (n = 1) was independently re-analyzed by molecular combing in a blinded fashion. The molecular combing results were identical to the Southern blot results in 75 (86%) of cases. All contractions (n = 7) and mosaics (n = 1) detected by Southern blot were confirmed by molecular combing. Of the 71 samples with normal Southern blot results, 67 (94%) had concordant molecular combing results. The four discrepancies were either mosaic (n = 2), rearranged (n = 1), or borderline by molecular combing (n = 1). All indeterminate Southern blot results (n = 6) were resolved by molecular combing as either normal (n = 4), borderline (n = 1), or rearranged (n = 1). The two borderline Southern blot results showed a D4Z4 contraction on the chr 4qA allele and a normal result by molecular combing. Molecular combing overcomes a number of technical limitations of Southern blot by providing direct visualization of D4Z4 macrosatellite repeat arrays on specific chr 4q and chr 10q alleles and more precise D4Z4 repeat sizing. This study suggests that molecular combing has superior analytical validity compared to Southern blot for determining D4Z4 contraction size, detecting mosaicism, and resolving borderline and indeterminate Southern blot results. Further studies are needed to establish the clinical validity and diagnostic accuracy of these findings in FSHD. PMID:26420234

  12. [Lethal sex].

    PubMed

    Rabinerson, David; Ben-Shitrit, Gadi; Glezerman, Marek

    2011-03-01

    Asphyxiophilic sex is a form of autoerotic activity, in which the user creates mechanical means (such as hanging or bondage) in order to achieve cerebral hypoxia, which, in turn, enhances sexual, as well as orgasmic, stimulus. Failure of safety mechanisms, created by the user, may lead to instant death as a result of asphyxiation or strangulation. This kind of sexual practice is more prevalent among men than in women. In cases of death, it is difficult to relate it to the sexual practice itself. Suicide and homicide are the main differential diagnoses. Closely related derivatives of asphyxiophilic sex are anesthesiophilia (inhalation of variable volatile substances) and electrophilia (use of electric current during sexual activity)--both also intended to enhance the sexual stimulation. These forms of sexual practice are less prevalent than asphyxiophilia. PMID:21574359

  13. A Study of the Effect of the Fringe Fields on the Electrostatic Force in Vertical Comb Drives

    PubMed Central

    Gallagher, Else; Moussa, Walied

    2014-01-01

    The equation that describes the relationship between the applied voltage and the resulting electrostatic force within comb drives is often used to assist in choosing the dimensions for their design. This paper re-examines how some of these dimensions—particularly the cross-sectional dimensions of the comb teeth—affect this relationship in vertical comb drives. The electrostatic forces in several vertical comb drives fabricated for this study were measured and compared to predictions made with four different mathematical models in order to explore the amount of complexity required within a model to accurately predict the electrostatic forces in the comb drives. PMID:25350504

  14. A Fine-Tooth Comb to Measure the Accelerating Universe

    NASA Astrophysics Data System (ADS)

    2008-09-01

    Astronomical instruments needed to answer crucial questions, such as the search for Earth-like planets or the way the Universe expands, have come a step closer with the first demonstration at the telescope of a new calibration system for precise spectrographs. The method uses a Nobel Prize-winning technology called a 'laser frequency comb', and is published in this week's issue of Science. Uncovering the disc ESO PR Photo 26a/08 A Laser Comb for Astronomy "It looks as if we are on the way to fulfil one of astronomers' dreams," says team member Theodor Hänsch, director at the Max Planck Institute for Quantum Optics (MPQ) in Germany. Hänsch, together with John Hall, was awarded the 2005 Nobel Prize in Physics for work including the frequency comb technique. Astronomers use instruments called spectrographs to spread the light from celestial objects into its component colours, or frequencies, in the same way water droplets create a rainbow from sunlight. They can then measure the velocities of stars, galaxies and quasars, search for planets around other stars, or study the expansion of the Universe. A spectrograph must be accurately calibrated so that the frequencies of light can be correctly measured. This is similar to how we need accurate rulers to measure lengths correctly. In the present case, a laser provides a sort of ruler, for measuring colours rather than distances, with an extremely accurate and fine grid. New, extremely precise spectrographs will be needed in experiments planned for the future European Extremely Large Telescope (E-ELT), which is being designed by ESO, the European Southern Observatory. These new spectrographs will need to be calibrated with even more accurate 'rulers'. In fact, they must be accurate to about one part in 30 billions - a feat equivalent to measuring the circumference of the Earth to about a millimetre! "We'll need something beyond what current technology can offer, and that's where the laser frequency comb comes in. It is

  15. Noise-Immune Cavity-Enhanced Optical Frequency Comb Spectroscopy

    NASA Astrophysics Data System (ADS)

    Rutkowski, Lucile; Khodabakhsh, Amir; Johanssson, Alexandra C.; Foltynowicz, Aleksandra

    2015-06-01

    We present noise-immune cavity-enhanced optical frequency comb spectroscopy (NICE-OFCS), a recently developed technique for sensitive, broadband, and high resolution spectroscopy. In NICE-OFCS an optical frequency comb (OFC) is locked to a high finesse cavity and phase-modulated at a frequency precisely equal to (a multiple of) the cavity free spectral range. Since each comb line and sideband is transmitted through a separate cavity mode in exactly the same way, any residual frequency noise on the OFC relative to the cavity affects each component in an identical manner. The transmitted intensity contains a beat signal at the modulation frequency that is immune to frequency-to-amplitude noise conversion by the cavity, in a way similar to continuous wave noise-immune cavity-enhanced optical heterodyne molecular spectroscopy (NICE-OHMS). The light transmitted through the cavity is detected with a fast-scanning Fourier-transform spectrometer (FTS) and the NICE-OFCS signal is obtained by fast Fourier transform of the synchronously demodulated interferogram. Our NICE-OFCS system is based on an Er:fiber femtosecond laser locked to a cavity with a finesse of ˜9000 and a fast-scanning FTS equipped with a high-bandwidth commercial detector. We measured NICE-OFCS signals from the 3νb{1}+νb{3} overtone band of CO_2 around 1.57 μm and achieved absorption sensitivity 6.4×10-11cm-1 Hz-1/2 per spectral element, corresponding to a minimum detectable CO_2 concentration of 25 ppb after 330 s integration time. We will describe the principles of the technique and its technical implementation, and discuss the spectral lineshapes of the NICE-OFCS signals. A. Khodabakhsh, C. Abd Alrahman, and A. Foltynowicz, Opt. Lett. 39, 5034-5037 (2014). J. Ye, L. S. Ma, and J. L. Hall, J. Opt. Soc. Am. B 15, 6-15 (1998). A. Khodabakhsh, A. C. Johansson, and A. Foltynowicz, Appl. Phys. B (2015) doi:10.1007/s00340-015-6010-7.

  16. Doppler-Free Two-Photon Absorption Spectroscopy of Naphthalene Assisted by AN Optical Frequency Comb

    NASA Astrophysics Data System (ADS)

    Nishiyama, Akiko; Matsuba, Ayumi; Misono, Masatoshi

    2014-06-01

    Optical frequency combs are powerful tools for precise frequency measurements in various wavelength regions. The combs have been applied not only to metrology, but also to molecular spectroscopy. Recently, we studied high resolution spectroscopy of iodine molecule assisted by an optical frequency comb. In the study, the comb was used for frequency calibration of a scanning dye laser. In this study, we developed a frequency calibration scheme with a comb and an acousto-optic modulator to realize more precise frequency measurement in a wide frequency range. And the frequency calibration scheme was applied to Doppler-free two-photon absorption (DFTPA) spectroscopy of naphthalene. Naphthalene is one of the prototypical aromatic molecules, and its detailed structure and dynamics in excited states have been reported. We measured DFTPA spectra of A^1B1u(v4=1) ← X^1A_g(v=0) transition around 298 nm. A part of obtained spectra is shown in the figure. The spectral lines are rotationally resolved and the resolution is about 100 kHz. The horizontal axis was calibrated by the developed frequency calibration system employing the comb. The uncertainties of the calibrated frequencies were determined by the fluctuations of the comb modes which were stabilized to a GPS-disciplined clock. A. Nishiyama, D. Ishikawa, and M. Misono, J. Opt. Soc. Am. B 30, 2107 (2013).

  17. Towards efficient octave-spanning comb with micro-structured crystalline resonator

    NASA Astrophysics Data System (ADS)

    Grudinin, Ivan S.; Yu, Nan

    2015-03-01

    Optical frequency combs, typically produced by mode locked lasers, have revolutionized many applications in science and technology. Frequency combs were recently generated by micro resonators through nonlinear Kerr processes. However, the comb span from micro resonators was found to be limited by resonator dispersion and mode spectrum. While dispersion engineering has been reported in on-chip devices, monolithic crystalline resonators offer an advantage of high optical quality factor. Moreover, most resonators used for comb generation support many mode families, leading to unavoidable crossings in resonator spectrum. Such crossings strongly influence comb dynamics and may prevent stable coherent mode-locking and soliton states. We report a new crystalline resonator approach supporting dispersion control and single mode spectrum while maintaining high quality factor. Dispersion engineering by waveguide micro-structuring is used to flatten the dispersion in our MgF2 resonator. Both absolute magnitude of dispersion and its slopes can be altered over a wavelength span exceeding an octave. Dispersion flattening leads to generation of an octave-spanning frequency comb with repetition rate of 46 GHz and coupled pump power below 100 mW. We also demonstrate that the micro- structuring dispersion engineering approach can be used to achieve flattened and anomalous dispersion in a CaF2 resonator near 1550 nm wavelength. In addition, we describe observation of discrete steps between the modulation instability states of the primary comb and on the three-stage comb unfolding dynamics. The micro-structured resonators may enable efficient low repetition rate coherent octave spanning frequency combs without external broadening, ideal for applications in optical frequency synthesis, metrology, spectroscopy, and communications.

  18. The ability of White Leghorn hens with trimmed comb and wattles to thermoregulate.

    PubMed

    Al-Ramamneh, D S; Makagon, M M; Hester, P Y

    2016-08-01

    It is estimated that each year over 19 million pullets in the United States have their combs partially trimmed at a young age to improve egg production and feed efficiency. A possible disadvantage of trimming is that the comb and wattles may be essential for thermoregulation during hot weather allowing for conductive cooling of the blood through vasodilation of superficial vessels in these integumentary tissues. The objective of this study was to investigate the effects of partial comb and wattle removal, performed at 21 d of age, on the ability of White Leghorns to thermoregulate before, during, and after an imposed heating episode that averaged 34.6°C for 50.5 h. An increase in mortality at 20 h and body temperature at 48 h post initiation of the heating episode demonstrated that hens with trimmed comb and wattles were not able to cope with heat stress as effectively as controls. The increase in wattle temperature in controls as compared to trimmed hens during the heating episode and following heat stress provides supportive evidence that blood pools to the peripheral surface for conductive heat loss. During high temperatures typical of summer, trimmed hens attempted to compensate for their lack of ability to transfer heat from their comb and wattles to the environment through increased proportion of panting and wing spreading. Under less extreme conditions with lowered ambient temperatures, the trimming of the comb and wattles did not impair the ability of hens to thermoregulate, as body temperatures and behavior were similar to controls with no mortality. Egg weight was the only production parameter adversely affected by the trimming of the comb and wattles as compared to controls. The implication is that hens need their combs and wattles to thermoregulate effectively during periods of high environmental temperature. Pullets should not be subjected to a comb and wattle trim if they are housed in laying facilities that are not appropriately cooled during the

  19. Ornamental comb colour predicts T-cell-mediated immunity in male red grouse Lagopus lagopus scoticus

    NASA Astrophysics Data System (ADS)

    Mougeot, Francois

    2008-02-01

    Sexual ornaments might reliably indicate the ability to cope with parasites and diseases, and a better ability to mount a primary inflammatory response to a novel challenge. Carotenoid-based ornaments are amongst the commonest sexual signals of birds and often influence mate choice. Because carotenoids are immuno-stimulants, signallers may trade-off allocating these to ornamental colouration or using them for immune responses, so carotenoid-based ornaments might be particularly useful as honest indicators of immuno-compentence. Tetraonid birds, such as the red grouse Lagopus lagopus scoticus, exhibit supra-orbital yellow red combs, a conspicuous ornament which functions in intra- and inter-sexual selection. The colour of combs is due to epidermal pigmentation by carotenoids, while their size is testosterone-dependent. In this study, I investigated whether comb characteristics, and in particular, comb colour, indicated immuno-competence in free-living male red grouse. I assessed T-cell-mediated immunity using a standardised challenge with phytohaemagglutinin. Red grouse combs reflect in the red and in the ultraviolet spectrum of light, which is not visible to humans but that grouse most likely see, so I measured comb colour across the whole bird visible spectrum (300 700 nm) using a reflectance spectrometer. I found that males with bigger and redder combs, but with less ultraviolet reflectance, had greater T-cell-mediated immune response. Comb colour predicted T-cell-mediated immune response better than comb size, indicating that the carotenoid-based colouration of this ornament might reliably signal this aspect of male quality.

  20. High spectral purity Kerr frequency comb radio frequency photonic oscillator.

    PubMed

    Liang, W; Eliyahu, D; Ilchenko, V S; Savchenkov, A A; Matsko, A B; Seidel, D; Maleki, L

    2015-01-01

    Femtosecond laser-based generation of radio frequency signals has produced astonishing improvements in achievable spectral purity, one of the basic features characterizing the performance of an radio frequency oscillator. Kerr frequency combs hold promise for transforming these lab-scale oscillators to chip-scale level. In this work we demonstrate a miniature 10 GHz radio frequency photonic oscillator characterized with phase noise better than -60 dBc Hz(-1) at 10 Hz, -90 dBc Hz(-1) at 100 Hz and -170 dBc Hz(-1) at 10 MHz. The frequency stability of this device, as represented by Allan deviation measurements, is at the level of 10(-10) at 1-100 s integration time-orders of magnitude better than existing radio frequency photonic devices of similar size, weight and power consumption. PMID:26260955

  1. Charge-optimized many-body (COMB) potential for zirconium

    NASA Astrophysics Data System (ADS)

    Noordhoek, Mark J.; Liang, Tao; Lu, Zizhe; Shan, Tzu-Ray; Sinnott, Susan B.; Phillpot, Simon R.

    2013-10-01

    An interatomic potential for zirconium is developed within the charge-optimized many-body (COMB) formalism. The potential correctly predicts the hexagonal close-packed (HCP) structure as the ground state with cohesive energy, lattice parameters, and elastic constants matching experiment well. The most stable interstitial position is the basal octahedral followed by basal split, in agreement with recent first principles calculations. Stacking fault energies within the prism and basal planes satisfactorily match first principles calculations. A tensile test using nanocrystalline zirconium exhibits both prismatic {1 0 1bar 0}<1 1 2bar 0> slip and pyramidal {1 1 2bar 2}<1 1 2bar 3bar> slip, showing the model is capable of reproducing the mechanical deformation modes observed in experiments.

  2. High performance tunnel injection quantum dot comb laser

    SciTech Connect

    Lee, C.-S.; Guo Wei; Basu, Debashish; Bhattacharya, Pallab

    2010-03-08

    A high-speed multiwavelength quantum dot comb laser, grown by molecular beam epitaxy, is demonstrated. The device is characterized with a 75.9 nm (full width at half maximum) and a 91.4 nm (DELTA{sub -15dB}) wide lasing spectrum. There are 105 and 185 simultaneously emitted longitudinal modes with a maximum channel intensity nonuniformity of less than 3 dB in the spectral range of 1231-1252 nm and 1274-1311 nm, respectively, for a laser with 1040 mum cavity length. The channel spacing can be tuned with cavity length and remains invariant in the temperature range of 300-323 K. The small signal modulation bandwidth is 7.5 GHz.

  3. Ptychographic hyperspectral spectromicroscopy with an extreme ultraviolet high harmonic comb.

    PubMed

    Zhang, Bosheng; Gardner, Dennis F; Seaberg, Matthew H; Shanblatt, Elisabeth R; Porter, Christina L; Karl, Robert; Mancuso, Christopher A; Kapteyn, Henry C; Murnane, Margaret M; Adams, Daniel E

    2016-08-01

    We report a proof-of-principle demonstration of a new scheme of spectromicroscopy in the extreme ultraviolet (EUV) spectral range, where the spectral response of the sample at different wavelengths is imaged simultaneously. This scheme is enabled by combining ptychographic information multiplexing (PIM) with a tabletop EUV source based on high harmonic generation, where four spectrally narrow harmonics near 30 nm form a spectral comb structure. Extending PIM from previously demonstrated visible wavelengths to the EUV/X-ray wavelengths promises much higher spatial resolution and a more powerful spectral contrast mechanism, making PIM an attractive spectromicroscopy method in both microscopy and spectroscopy aspects. In addition to spectromicroscopy, this method images the multicolor EUV beam in situ, making this a powerful beam characterization technique. In contrast to other methods, the techniques described here use no hardware to separate wavelengths, leading to efficient use of the EUV radiation. PMID:27505837

  4. High spectral purity Kerr frequency comb radio frequency photonic oscillator

    PubMed Central

    Liang, W.; Eliyahu, D.; Ilchenko, V. S.; Savchenkov, A. A.; Matsko, A. B.; Seidel, D.; Maleki, L.

    2015-01-01

    Femtosecond laser-based generation of radio frequency signals has produced astonishing improvements in achievable spectral purity, one of the basic features characterizing the performance of an radio frequency oscillator. Kerr frequency combs hold promise for transforming these lab-scale oscillators to chip-scale level. In this work we demonstrate a miniature 10 GHz radio frequency photonic oscillator characterized with phase noise better than −60 dBc Hz−1 at 10 Hz, −90 dBc Hz−1 at 100 Hz and −170 dBc Hz−1 at 10 MHz. The frequency stability of this device, as represented by Allan deviation measurements, is at the level of 10−10 at 1–100 s integration time—orders of magnitude better than existing radio frequency photonic devices of similar size, weight and power consumption. PMID:26260955

  5. Supramolecular Polymerization from Polypeptide-Grafted Comb Polymers

    SciTech Connect

    Wang, Jing; Lu, Hua; Kamat, Ranjan K; Pingali, Sai Venkatesh; Urban, Volker S; Cheng, Jianjun; Lin, Yao

    2011-01-01

    The helical and tubular structures self-assembled from proteins have inspired scientists to design synthetic building blocks that can be 'polymerized' into supramolecular polymers through coordinated noncovalent interactions. However, cooperative supramolecular polymerization from large, synthetic macromolecules remains a challenge because of the difficulty of controlling the structure and interactions of macromolecular monomers. Herein we report the synthesis of polypeptide-grafted comb polymers and the use of their tunable secondary interactions in solution to achieve controlled supramolecular polymerization. The resulting tubular supramolecular structures, with external diameters of hundreds of nanometers and lengths of tens of micrometers, are stable and resemble to some extent biological superstructures assembled from proteins. This study shows that highly specific intermolecular interactions between macromolecular monomers can enable the cooperative growth of supramolecular polymers. The general applicability of this strategy was demonstrated by carrying out supramolecular polymerization from gold nanoparticles grafted with the same polypeptides on the surface.

  6. Direct frequency comb two-photon laser cooling and trapping

    NASA Astrophysics Data System (ADS)

    Long, Xueping; Jayich, Andrew; Campbell, Wesley C.

    2016-05-01

    Generating and manipulating high energy photons for spectroscopy on electric dipole transitions of atoms and molecules with deeply bound valence electrons is difficult. Further, laser cooling of such species is even more challenging for lack of laser power. A possible solution is to drive two-photon transitions. This may alleviate the photon energy problem and open the door to cold, trapped samples of highly desirable species with tightly bound electrons. We perform a proof of principle experiment with rubidium by driving a two-photon transition with an optical frequency comb. We perform optical cooling and extend this technique to trapping, where we are able to make a magneto-optical trap in one dimension. This work is supported by the National Science Foundation CAREER program.

  7. High spectral purity Kerr frequency comb radio frequency photonic oscillator

    NASA Astrophysics Data System (ADS)

    Liang, W.; Eliyahu, D.; Ilchenko, V. S.; Savchenkov, A. A.; Matsko, A. B.; Seidel, D.; Maleki, L.

    2015-08-01

    Femtosecond laser-based generation of radio frequency signals has produced astonishing improvements in achievable spectral purity, one of the basic features characterizing the performance of an radio frequency oscillator. Kerr frequency combs hold promise for transforming these lab-scale oscillators to chip-scale level. In this work we demonstrate a miniature 10 GHz radio frequency photonic oscillator characterized with phase noise better than -60 dBc Hz-1 at 10 Hz, -90 dBc Hz-1 at 100 Hz and -170 dBc Hz-1 at 10 MHz. The frequency stability of this device, as represented by Allan deviation measurements, is at the level of 10-10 at 1-100 s integration time--orders of magnitude better than existing radio frequency photonic devices of similar size, weight and power consumption.

  8. Spectroscopy of lithium atoms using an optical frequency comb

    NASA Astrophysics Data System (ADS)

    Stalnaker, Jason; Almaguer, Jose; Sherry, Leanne

    2011-05-01

    The atomic structure of lithium (Li) has aroused a significant amount theoretical and experimental interest as a system in which precision atomic calculations and spectroscopic measurements can be united to yield scientifically significant results. While there have been many experimental investigations of Li spectroscopy, particularly of the isotope shifts and hyperfine structure on the 22S1 / 2 --> 22P1 / 2 , 3 / 2 (D 1 , D 2) transitions, they suffer from significant disagreements and systematic effects. By utilizing the optical-to-microwave frequency conversion made possible by a stabilized optical frequency comb, we will be able to resolve the discrepancies and measure the optical frequencies of the D 1 and D 2 transitions to an accuracy of 5 kHz. We present preliminary data from an atomic beam source and discuss future plans to develop a laser-cooled and trapped source. Supported by NIST Precision Measurements Grant.

  9. Manipulation of the generation dynamics of a microresonator-based frequency comb via selective mode filtering

    NASA Astrophysics Data System (ADS)

    Bao, Chengying; Xiao, Xiaosheng; Yang, Changxi

    2013-05-01

    We suggest a scheme to manipulate the generation dynamics of high-Q microresonator-based frequency combs (microcombs). Our simulation demonstrates that a certain subfamily of comb teeth can be suppressed via selectively filtering out limited modes, from which high-quality mode-locked pulses can be generated. Mode-pulling in microcomb generation is also analyzed quantitatively to explain the results. These results can help us better understand microcomb generation dynamics and will be beneficial in controlling the generated comb line number and spacing.

  10. Spatiotemporal Lugiato-Lefever formalism for Kerr-comb generation in whispering-gallery-mode resonators

    NASA Astrophysics Data System (ADS)

    Chembo, Yanne K.; Menyuk, Curtis R.

    2013-05-01

    We demonstrate that frequency (Kerr) comb generation in whispering-gallery-mode resonators can be modeled by a variant of the Lugiato-Lefever equation that includes higher-order dispersion and nonlinearity. This spatiotemporal model allows us to explore pulse formation in which a large number of modes interact cooperatively. Pulse formation is shown to play a critical role in comb generation, and we find conditions under which single pulses (dissipative solitons) and multiple pulses (rolls) form. We show that a broadband comb is the spectral signature of a dissipative soliton, and we also show that these solitons can be obtained by using a weak anomalous dispersion and subcritical pumping.

  11. Quantum-fluctuation-initiated coherence in multioctave Raman optical frequency combs.

    PubMed

    Wang, Y Y; Wu, Chunbai; Couny, F; Raymer, M G; Benabid, F

    2010-09-17

    We show experimentally and theoretically that the spectral components of a multioctave frequency comb spontaneously created by stimulated Raman scattering in a hydrogen-filled hollow-core photonic crystal fiber exhibit strong self-coherence and mutual coherence within each 12 ns driving laser pulse. This coherence arises in spite of the field's initiation being from quantum zero-point fluctuations, which causes each spectral component to show large phase and energy fluctuations. This points to the possibility of an optical frequency comb with nonclassical correlations between all comb lines. PMID:20867639

  12. Origin and stability of dark pulse Kerr combs in normal dispersion resonators.

    PubMed

    Parra-Rivas, Pedro; Gomila, Damià; Knobloch, Edgar; Coen, Stéphane; Gelens, Lendert

    2016-06-01

    We analyze dark pulse Kerr frequency combs in optical resonators with normal group-velocity dispersion using the Lugiato-Lefever model. We show that in the time domain the combs correspond to interlocked switching waves between the upper and lower homogeneous states, and explain how this fact accounts for many of their experimentally observed properties. Modulational instability does not play any role in their existence. We provide a detailed map indicating for which parameters stable dark pulse Kerr combs can be found, and how they are destabilized for increasing values of frequency detuning. PMID:27244374

  13. Glucose sensor based on redox-cycling between selectively modified and unmodified combs of carbon interdigitated array nanoelectrodes.

    PubMed

    Sharma, Deepti; Lim, Yeongjin; Lee, Yunjeong; Shin, Heungjoo

    2015-08-19

    We present a novel electrochemical glucose sensor employing an interdigitated array (IDA) of 1:1 aspect ratio carbon nanoelectrodes for the electrochemical-enzymatic redox cycling of redox species (ferricyanide/ferrocyanide) between glucose oxidase (GOx) and the two comb-shaped nanoelectrodes of the IDA. The carbon nanoelectrodes were fabricated using a simple, cost-effective, reproducible microfabrication technology known as the carbon-microelectromechanical-systems (C-MEMS) process. One comb (comb 1) of the IDA was selectively modified with GOx via the electrochemical reduction of an aryl diazonium salt, while the other comb (comb 2) remained unmodified; this facilitates electrochemically more active surface of comb 2, resulting in sensitive glucose detection. Ferricyanide is reduced to ferrocyanide by the GOx in the presence of glucose, and ferrocyanide diffuses to both combs of the IDA where it is oxidized. The limited electrochemical current collection at the surface-modified comb 1 is counterbalanced by the efficient redox cycling between the enzyme sites at comb 1 and the bare carbon surface of comb 2. Reducing the electrode-to-electrode gap between the two combs (gap = 1.9 μm) increases the diffusion flux of redox species at comb 2 hence, enhanced the sensitivity and limit of detection of the glucose sensor by ∼2.3 and ∼295 times, respectively at comb 2 compared to comb 1. The developed IDA-based glucose sensor demonstrated good amperometric response to glucose, affording two linear ranges from 0.001 to 1 mM and from 1 to 10 mM, with limits of detection of 0.4 and 61 μM and sensitivities of 823.2 and 70.0 μA mM(-1) cm(-2), respectively. PMID:26343443

  14. Phase-dependent interference between frequency doubled comb lines in a χ(2) phase-matched aluminum nitride microring.

    PubMed

    Jung, Hojoong; Guo, Xiang; Zhu, Na; Papp, Scott B; Diddams, Scott A; Tang, Hong X

    2016-08-15

    Nonlinear optical conversion with frequency combs is important for self-referencing and for generating shorter wavelength combs. Here we demonstrate efficient frequency comb doubling through the combination of second-harmonic generation (SHG) and sum-frequency generation (SFG) of an input comb with a high Q, phase-matched χ(2) microring resonator. Phase coherence of the SHG and SFG nonlinear conversion processes is confirmed by sinusoidal phase-dependent interference between frequency doubled comb lines. PMID:27519079

  15. An octave-spanning mid-infrared frequency comb generated in a silicon nanophotonic wire waveguide

    NASA Astrophysics Data System (ADS)

    Kuyken, Bart; Ideguchi, Takuro; Holzner, Simon; Yan, Ming; Hänsch, Theodor W.; van Campenhout, Joris; Verheyen, Peter; Coen, Stéphane; Leo, Francois; Baets, Roel; Roelkens, Gunther; Picqué, Nathalie

    2015-02-01

    Laser frequency combs, sources with a spectrum consisting of hundred thousands evenly spaced narrow lines, have an exhilarating potential for new approaches to molecular spectroscopy and sensing in the mid-infrared region. The generation of such broadband coherent sources is presently under active exploration. Technical challenges have slowed down such developments. Identifying a versatile highly nonlinear medium for significantly broadening a mid-infrared comb spectrum remains challenging. Here we take a different approach to spectral broadening of mid-infrared frequency combs and investigate CMOS-compatible highly nonlinear dispersion-engineered silicon nanophotonic waveguides on a silicon-on-insulator chip. We record octave-spanning (1,500-3,300 nm) spectra with a coupled input pulse energy as low as 16 pJ. We demonstrate phase-coherent comb spectra broadened on a room-temperature-operating CMOS-compatible chip.

  16. Mode-resolved frequency comb interferometry for high-accuracy long distance measurement

    PubMed Central

    van den Berg, Steven. A.; van Eldik, Sjoerd; Bhattacharya, Nandini

    2015-01-01

    Optical frequency combs have developed into powerful tools for distance metrology. In this paper we demonstrate absolute long distance measurement using a single femtosecond frequency comb laser as a multi-wavelength source. By applying a high-resolution spectrometer based on a virtually imaged phased array, the frequency comb modes are resolved spectrally to the level of an individual mode. Having the frequency comb stabilized against an atomic clock, thousands of accurately known wavelengths are available for interferometry. From the spectrally resolved output of a Michelson interferometer a distance is derived. The presented measurement method combines spectral interferometry, white light interferometry and multi-wavelength interferometry in a single scheme. Comparison with a fringe counting laser interferometer shows an agreement within <10−8 for a distance of 50 m. PMID:26419282

  17. Self-oscillating optical frequency comb generator based on an optoelectronic oscillator employing cascaded modulators.

    PubMed

    Dai, Jian; Xu, Xingyuan; Wu, Zhongle; Dai, Yitang; Yin, Feifei; Zhou, Yue; Li, Jianqiang; Xu, Kun

    2015-11-16

    An ultraflat self-oscillating optical frequency comb generator based on an optoelectronic oscillator employing cascaded modulators was proposed and experimentally demonstrated. By incorporating the optoelectronic oscillation loop with cascaded modulators into the optical frequency comb generator, 11 ultraflat comb lines would be generated, and the frequency spacing is equal to the oscillation frequency of the OEO. 10 and 12GHz optical frequency combs are demonstrated with the spectral power variation below 0.82dB and 0.93dB respectively. The corresponding spectral pure microwave source are also generated and evaluated. The corresponding single-sideband phase noise are as low as -122dBc/Hz and -115 dBc/Hz at 10 kHz offset frequency. PMID:26698482

  18. Closed-form solutions and scaling laws for Kerr frequency combs

    NASA Astrophysics Data System (ADS)

    Renninger, William H.; Rakich, Peter T.

    2016-04-01

    A single closed-form analytical solution of the driven nonlinear Schrödinger equation is developed, reproducing a large class of the behaviors in Kerr-comb systems, including bright-solitons, dark-solitons, and a large class of periodic wavetrains. From this analytical framework, a Kerr-comb area theorem and a pump-detuning relation are developed, providing new insights into soliton- and wavetrain-based combs along with concrete design guidelines for both. This new area theorem reveals significant deviation from the conventional soliton area theorem, which is crucial to understanding cavity solitons in certain limits. Moreover, these closed-form solutions represent the first step towards an analytical framework for wavetrain formation, and reveal new parameter regimes for enhanced Kerr-comb performance.

  19. Monolithically integrated low linewidth comb source using gain switched slotted Fabry-Perot lasers.

    PubMed

    Alexander, J K; Morrissey, P E; Yang, H; Yang, M; Marraccini, P J; Corbett, B; Peters, F H

    2016-04-18

    A monolithically integrated low linewidth optical comb is demonstrated by gain switching of a three-section laser device. The device consists of a slave and master section separated by a shared slotted mirror section. Wavelength tunability has been demonstrated by varying the electrical bias of each section. The number of comb lines is shown to almost double with the addition of optical injection from the master section into the slave. The unmodulated device has a full width half max linewidth of ∼ 500 kHz, while the comb line set were measured to be ∼ 600 kHz, with little degradation as a result of gain switching. The FSR (free spectral range) of the demonstrated comb is 4 GHz, which is tunable within the bandwidth of the device, with a central wavelength of 1580.3 nm. PMID:27137237

  20. Mode-resolved frequency comb interferometry for high-accuracy long distance measurement

    NASA Astrophysics Data System (ADS)

    van den Berg, Steven. A.; van Eldik, Sjoerd; Bhattacharya, Nandini

    2015-09-01

    Optical frequency combs have developed into powerful tools for distance metrology. In this paper we demonstrate absolute long distance measurement using a single femtosecond frequency comb laser as a multi-wavelength source. By applying a high-resolution spectrometer based on a virtually imaged phased array, the frequency comb modes are resolved spectrally to the level of an individual mode. Having the frequency comb stabilized against an atomic clock, thousands of accurately known wavelengths are available for interferometry. From the spectrally resolved output of a Michelson interferometer a distance is derived. The presented measurement method combines spectral interferometry, white light interferometry and multi-wavelength interferometry in a single scheme. Comparison with a fringe counting laser interferometer shows an agreement within <10-8 for a distance of 50 m.

  1. Closed-form solutions and scaling laws for Kerr frequency combs

    PubMed Central

    Renninger, William H.; Rakich, Peter T.

    2016-01-01

    A single closed-form analytical solution of the driven nonlinear Schrödinger equation is developed, reproducing a large class of the behaviors in Kerr-comb systems, including bright-solitons, dark-solitons, and a large class of periodic wavetrains. From this analytical framework, a Kerr-comb area theorem and a pump-detuning relation are developed, providing new insights into soliton- and wavetrain-based combs along with concrete design guidelines for both. This new area theorem reveals significant deviation from the conventional soliton area theorem, which is crucial to understanding cavity solitons in certain limits. Moreover, these closed-form solutions represent the first step towards an analytical framework for wavetrain formation, and reveal new parameter regimes for enhanced Kerr-comb performance. PMID:27108810

  2. Design of an Electrostatic Comb Actuator Based on Finite Element Method

    NASA Astrophysics Data System (ADS)

    Mon, Thet Thet; Ghazalli, Zakri; Ahmad, Asnul Hadi; Ismail, Mohd Fazli; Muhamad, Khairul Fikri

    2011-05-01

    Electrostatic comb actuators were designed using finite element modeling and analysis, so-called finite element method (FEM). Design objective was to generate maximum actuating force within the constraints. 2D and 3D FE models of the comb structures were developed in general-purpose FE code. The element geometries were 4-node plate element for 2D model and 8-node brick element for 3D models. Electrostatic field strength and voltage analysis of the FE models were performed to compute generated voltage and electrostatic force in the structure. Subsequently done was the structural analysis to examine structural response to the electrostatic force. The initial finite element model was verified with the published experimental result. Based on the amount of force generated and lateral deflection of the comb fingers, the best possible design of choice was determined. The finite element computations show that the comb structure having high aspect ratio with smaller gaps can provide higher actuation force.

  3. Characteristics of distributed-type inorganic electroluminescence panels with comb-shaped electrodes

    NASA Astrophysics Data System (ADS)

    Yamamoto, Shin-Ichi; Uraoka, Yukiharu; Taguchi, Nobuyoshi; Nonaka, Toshihiro

    2013-09-01

    We deposited comb electrodes with narrow gaps between the teeth on a glass substrate, thus realizing a high electric field intensity that cannot be achieved with conventional structures. Au electrodes are deposited to form a comb shape and then spin-coated with a phosphor layer obtained by mixing ZnS phosphor particles with resins in a certain ratio. An AC voltage was applied to the gaps between the teeth of the comb electrode to emit light, from which the luminance was measured for different electric field intensities. The luminance was not affected by the transmittance of the electrodes themselves when measured from the phosphor layer side. Therefore, it may be possible to produce a display that does not require transparent electrodes by using the phosphor layer side of a device with comb electrodes made of metals, such as Au, for the display.

  4. Intracavity characterization of micro-comb generation in the single-soliton regime.

    PubMed

    Wang, Pei-Hsun; Jaramillo-Villegas, Jose A; Xuan, Yi; Xue, Xiaoxiao; Bao, Chengying; Leaird, Daniel E; Qi, Minghao; Weiner, Andrew M

    2016-05-16

    Soliton formation in on-chip micro-comb generation balances cavity dispersion and nonlinearity and allows coherent, low-noise comb operation. We study the intracavity waveform of an on-chip microcavity soliton in a silicon nitride microresonator configured with a drop port. Whereas combs measured at the through port are accompanied by a very strong pump line which accounts for >99% of the output power, our experiments reveal that inside the microcavity, most of the power is in the soliton. Time-domain measurements performed at the drop port provide information that directly reflects the intracavity field. Data confirm a train of bright, close to bandwidth-limited pulses, accompanied by a weak continuous wave (CW) background with a small phase shift relative to the comb. PMID:27409909

  5. Mode-resolved frequency comb interferometry for high-accuracy long distance measurement.

    PubMed

    van den Berg, Steven A; van Eldik, Sjoerd; Bhattacharya, Nandini

    2015-01-01

    Optical frequency combs have developed into powerful tools for distance metrology. In this paper we demonstrate absolute long distance measurement using a single femtosecond frequency comb laser as a multi-wavelength source. By applying a high-resolution spectrometer based on a virtually imaged phased array, the frequency comb modes are resolved spectrally to the level of an individual mode. Having the frequency comb stabilized against an atomic clock, thousands of accurately known wavelengths are available for interferometry. From the spectrally resolved output of a Michelson interferometer a distance is derived. The presented measurement method combines spectral interferometry, white light interferometry and multi-wavelength interferometry in a single scheme. Comparison with a fringe counting laser interferometer shows an agreement within <10(-8) for a distance of 50 m. PMID:26419282

  6. Comb structure analysis of the capacitive sensitive element in MEMS-accelerometer

    NASA Astrophysics Data System (ADS)

    Shalimov, Andrew; Timoshenkov, Sergey; Korobova, Natalia; Golovinskiy, Maxim; Timoshenkov, Alexey; Zuev, Egor; Berezueva, Svetlana; Kosolapov, Andrey

    2015-05-01

    In this paper analysis of comb design for the sensing element MEMS accelerometer with longitudinal displacement of the inertial mass under the influence of acceleration to obtain the necessary parameters for the further construction of an electronic circuit for removal and signal processing has been done. Fixed on the stator the inertia mass has the ability to move under the influence of acceleration along the longitudinal structure. As a result the distance between the fixed and movable combs, and hence the capacitance in the capacitors have been changed. Measuring the difference of these capacitances you can estimate the value of the applied acceleration. Furthermore, managing combs that should apply an electrostatic force for artificial deviation of the inertial mass may be used for the initial sensitive elements culling. Also in this case there is a change of capacitances, which can be measured by the comb and make a decision about the spoilage presence or absence.

  7. Closed-form solutions and scaling laws for Kerr frequency combs.

    PubMed

    Renninger, William H; Rakich, Peter T

    2016-01-01

    A single closed-form analytical solution of the driven nonlinear Schrödinger equation is developed, reproducing a large class of the behaviors in Kerr-comb systems, including bright-solitons, dark-solitons, and a large class of periodic wavetrains. From this analytical framework, a Kerr-comb area theorem and a pump-detuning relation are developed, providing new insights into soliton- and wavetrain-based combs along with concrete design guidelines for both. This new area theorem reveals significant deviation from the conventional soliton area theorem, which is crucial to understanding cavity solitons in certain limits. Moreover, these closed-form solutions represent the first step towards an analytical framework for wavetrain formation, and reveal new parameter regimes for enhanced Kerr-comb performance. PMID:27108810

  8. Low-noise and broadband optical frequency comb generation based on an optoelectronic oscillator.

    PubMed

    Xie, Xiaopeng; Sun, Tao; Peng, Huanfa; Zhang, Cheng; Guo, Peng; Zhu, Lixin; Hu, Weiwei; Chen, Zhangyuan

    2014-02-15

    A novel scheme to generate broadband high-repetition-rate optical frequency combs and low phase noise microwave signals simultaneously is proposed and experimentally demonstrated. By incorporating an optical frequency comb generator in an optoelectronic oscillator loop, more than 200 lines are generated for a 25 GHz optical frequency comb, and the single-sideband phase noise is as low as -122  dBc/Hz at 10 kHz offset for the 25 GHz microwave signal. 10 and 20 GHz optical frequency combs and microwave signals are also generated. Unlike the microwave frequency synthesizer, the phase noise of the microwave signals generated by this new scheme is frequency independent. PMID:24562206

  9. An octave-spanning mid-infrared frequency comb generated in a silicon nanophotonic wire waveguide

    PubMed Central

    Kuyken, Bart; Ideguchi, Takuro; Holzner, Simon; Yan, Ming; Hänsch, Theodor W.; Van Campenhout, Joris; Verheyen, Peter; Coen, Stéphane; Leo, Francois; Baets, Roel; Roelkens, Gunther; Picqué, Nathalie

    2015-01-01

    Laser frequency combs, sources with a spectrum consisting of hundred thousands evenly spaced narrow lines, have an exhilarating potential for new approaches to molecular spectroscopy and sensing in the mid-infrared region. The generation of such broadband coherent sources is presently under active exploration. Technical challenges have slowed down such developments. Identifying a versatile highly nonlinear medium for significantly broadening a mid-infrared comb spectrum remains challenging. Here we take a different approach to spectral broadening of mid-infrared frequency combs and investigate CMOS-compatible highly nonlinear dispersion-engineered silicon nanophotonic waveguides on a silicon-on-insulator chip. We record octave-spanning (1,500–3,300 nm) spectra with a coupled input pulse energy as low as 16 pJ. We demonstrate phase-coherent comb spectra broadened on a room-temperature-operating CMOS-compatible chip. PMID:25697764

  10. Phase-locked, erbium-fiber-laser-based frequency comb in the near infrared.

    PubMed

    Washburn, Brian R; Diddams, Scott A; Newbury, Nathan R; Nicholson, Jeffrey W; Yan, Man F; Jørgensen, Carsten G

    2004-02-01

    A phase-locked frequency comb in the near infrared is demonstrated with a mode-locked, erbium-doped, fiber laser whose output is amplified and spectrally broadened in dispersion-flattened, highly nonlinear optical fiber to span from 1100 to >2200 nm. The supercontinuum output comprises a frequency comb with a spacing set by the laser repetition rate and an offset by the carrier-envelope offset frequency, which is detected with the standard f-to-2f heterodyne technique. The comb spacing and offset frequency are phase locked to a stable rf signal with a fiber stretcher in the laser cavity and by control of the pump laser power, respectively. This infrared comb permits frequency metrology experiments in the near infrared in a compact, fiber-laser-based system. PMID:14759041

  11. Stabilized frequency comb with a self-referenced femtosecond Cr:forsterite laser.

    PubMed

    Kim, K; Washburn, B R; Wilpers, G; Oates, C W; Hollberg, L; Newbury, N R; Diddams, S A; Nicholson, J W; Yan, M F

    2005-04-15

    A frequency comb is generated with a Cr:forsterite femtosecond laser, spectrally broadened through a highly nonlinear optical fiber to span from 1.0 to 2.2 ,m, and stabilized using the f-to-2f self-referencing technique. The repetition rate and the carrier-envelope offset frequency are stabilized to a hydrogen maser, calibrated by a cesium atomic fountain clock. Simultaneous frequency measurement of a 657-nm cw laser by use of the stabilized frequency combs from this Cr:forsterite system and a Ti:sapphire laser agree at the 10(-13) level. The frequency noise of the comb components is observed at 1064, 1314, and 1550 nm by comparing the measured beat frequencies between cw lasers and the supercontinuum frequency combs. PMID:15865403

  12. An Optical Frequency Comb Tied to GPS for Laser Frequency/Wavelength Calibration.

    PubMed

    Stone, Jack A; Egan, Patrick

    2010-01-01

    Optical frequency combs can be employed over a broad spectral range to calibrate laser frequency or vacuum wavelength. This article describes procedures and techniques utilized in the Precision Engineering Division of NIST (National Institute of Standards and Technology) for comb-based calibration of laser wavelength, including a discussion of ancillary measurements such as determining the mode order. The underlying purpose of these calibrations is to provide traceable standards in support of length measurement. The relative uncertainty needed to fulfill this goal is typically 10(-8) and never below 10(-12), very modest requirements compared to the capabilities of comb-based frequency metrology. In this accuracy range the Global Positioning System (GPS) serves as an excellent frequency reference that can provide the traceable underpinning of the measurement. This article describes techniques that can be used to completely characterize measurement errors in a GPS-based comb system and thus achieve full confidence in measurement results. PMID:27134794

  13. An Optical Frequency Comb Tied to GPS for Laser Frequency/Wavelength Calibration

    PubMed Central

    Stone, Jack A.; Egan, Patrick

    2010-01-01

    Optical frequency combs can be employed over a broad spectral range to calibrate laser frequency or vacuum wavelength. This article describes procedures and techniques utilized in the Precision Engineering Division of NIST (National Institute of Standards and Technology) for comb-based calibration of laser wavelength, including a discussion of ancillary measurements such as determining the mode order. The underlying purpose of these calibrations is to provide traceable standards in support of length measurement. The relative uncertainty needed to fulfill this goal is typically 10−8 and never below 10−12, very modest requirements compared to the capabilities of comb-based frequency metrology. In this accuracy range the Global Positioning System (GPS) serves as an excellent frequency reference that can provide the traceable underpinning of the measurement. This article describes techniques that can be used to completely characterize measurement errors in a GPS-based comb system and thus achieve full confidence in measurement results. PMID:27134794

  14. Sensitive and Instantaneous Molecular Detection from Broadband Cavity-Enhanced Dual Comb Spectroscopy

    NASA Astrophysics Data System (ADS)

    Bernhardt, B.; Ozawa, A.; Jacquey, M.; Jacquet, P.; Guelachvili, G.; Udem, T.; Holzwarth, R.; Kobayashi, Y.; Hänsch, T. W.; Picqué, N.

    2010-06-01

    Recent experiments have demonstrated that the precisely spaced spectral lines of a laser frequency comb can be harnessed for new techniques of multi-heterodyne Fourier transform spectroscopy (also called dual-comb spectroscopy) of molecules. In one such experiment, an absorbing molecular gas was placed inside an optical cavity that is matched to the laser resonator so that it is resonant for each comb line. The sensitivity for weak absorption is much enhanced, as in cavity ring-down spectroscopy. The light transmitted by the cavity is superimposed on a second frequency comb with slightly different repetition frequency. A single fast photodetector then produces an output signal with a comb of radio frequencies due to interference between pairs of optical comb lines. The optical spectrum is thus effectively mapped into the radio frequency regime, where it becomes accessible to fast digital signal processing. Experimental proof-of-principle is carried out in the near-infrared 1 μm region. An Yb-doped fiber frequency comb is coherently coupled to a passive resonator with a finesse of 1200, resulting in an effective interaction length between the light and the gas enhanced to 880m. The weak 3ν1 band of ammonia is rotationally resolved for the first time to our knowledge. Recording times of 18 μs are enough to span 220 cm-1 with a resolution of 0.15 cm-1. The signal to noise ratio of 380 leads to a minimum-detectable-absorption coefficient αmin of 3×10-8 cm-1 . B. Bernhardt, A. Ozawa, P. Jacquet, M. Jacquey, Y. Kobayashi, T. Udem, R. Holzwarth, G. Guelachvili, T.W. Hänsch, N. Picqué, Cavity-enhanced dual-comb spectroscopy, Nature Photonics 4, 55-57 (2010),

  15. Generation of wideband frequency combs by continuous-wave seeding of multistage mixers with synthesized dispersion.

    PubMed

    Myslivets, Evgeny; Kuo, Bill P P; Alic, Nikola; Radic, Stojan

    2012-01-30

    We numerically and experimentally demonstrate efficient generation of an equalized optical comb with 150-nm bandwidth. The comb was generated by low-power, continuous-wave seeds, eliminating the need for pulsed laser sources. The new architecture relies on efficient creation of higher-order mixing tones in phase-matched nonlinear fiber stages separated by a linear compressor. Wideband generation was enabled by precise dispersion engineering of multiple-stage parametric mixers. PMID:22330571

  16. A new method for determining the plasma electron density using optical frequency comb interferometer

    SciTech Connect

    Arakawa, Hiroyuki Tojo, Hiroshi; Sasao, Hajime; Kawano, Yasunori; Itami, Kiyoshi

    2014-04-15

    A new method of plasma electron density measurement using interferometric phases (fractional fringes) of an optical frequency comb interferometer is proposed. Using the characteristics of the optical frequency comb laser, high density measurement can be achieved without fringe counting errors. Simulations show that the short wavelength and wide wavelength range of the laser source and low noise in interferometric phases measurements are effective to reduce ambiguity of measured density.

  17. Phase velocity spectrum analysis for a time delay comb transducer for guided wave mode excitation

    SciTech Connect

    Quarry, M J; Rose, J L

    2000-09-26

    A theoretical model for the analysis of ultrasonic guided wave mode excitation of a comb transducer with time delay features was developed. Time delay characteristics are included via a Fourier transform into the frequency domain. The phase velocity spectrum can be used to determine the mode excitation on the phase velocity dispersion curves for a given structure. Experimental and theoretical results demonstrate the tuning of guided wave modes using a time delay comb transducer.

  18. Sex-linked dominant

    MedlinePlus

    Inheritance - sex-linked dominant; Genetics - sex-linked dominant; X-linked dominant; Y-linked dominant ... one of the sex chromosomes, which are the X and Y chromosomes. Dominant inheritance occurs when an ...

  19. Sex-linked dominant

    MedlinePlus

    Inheritance - sex-linked dominant; Genetics - sex-linked dominant; X-linked dominant; Y-linked dominant ... type of chromosome that is affected (autosomal or sex chromosome). It also depends on whether the trait ...

  20. Toward a broadband astro-comb: effects of nonlinear spectral broadening in optical fibers.

    PubMed

    Chang, Guoqing; Li, Chih-Hao; Phillips, David F; Walsworth, Ronald L; Kärtner, Franz X

    2010-06-01

    We propose and analyze a new approach to generate a broadband astro-comb by spectral broadening of a narrowband astro-comb inside a highly nonlinear optical fiber. Numerical modeling shows that cascaded four-wave-mixing dramatically degrades the input comb's side-mode suppression and causes side-mode amplitude asymmetry. These two detrimental effects can systematically shift the center-of-gravity of astro-comb spectral lines as measured by an astrophysical spectrograph with resolution approximately 100,000; and thus lead to wavelength calibration inaccuracy and instability. Our simulations indicate that this performance penalty, as a result of nonlinear spectral broadening, can be compensated by using a filtering cavity configured for double-pass. As an explicit example, we present a design based on an Yb-fiber source comb (with 1 GHz repetition rate) that is filtered by double-passing through a low finesse cavity (finesse = 208), and subsequent spectrally broadened in a 2-cm, SF6-glass photonic crystal fiber. Spanning more than 300 nm with 16 GHz line spacing, the resulting astro-comb is predicted to provide 1 cm/s (approximately 10 kHz) radial velocity calibration accuracy for an astrophysical spectrograph. Such extreme performance will be necessary for the search for and characterization of Earth-like extra-solar planets, and in direct measurements of the change of the rate of cosmological expansion. PMID:20588402

  1. Coherent dual-comb interferometry with quasi-integer-ratio repetition rates.

    PubMed

    Hébert, Nicolas Bourbeau; Boudreau, Sylvain; Genest, Jérôme; Deschênes, Jean-Daniel

    2014-11-17

    We demonstrate a generalized method for dual-comb interferometry that involves the use of two frequency combs with quasi-integer-ratio repetition rates. We use a 16.67 MHz comb to probe an 80-cm-long ring cavity and a 100 MHz comb to asynchronously sample its impulse response. The resulting signal can be seen as six time-multiplexed independent interferograms. We perform a deconvolution of the photodetector's impulse response to prevent any crosstalk between these multiplexed data sets. The measurement is then demultiplexed and corrected with referencing signals. We obtain a measurement with a spectral point spacing of 16.67 MHz and a spectral SNR of 55 dB by averaging 15,000 interferograms, corresponding to a measurement time of 500 s. Compared to conventional dual-comb spectroscopy, this generalized technique allows to either reduce the spectral point spacing or the acquisition time by changing the repetition rate of only one of the combs. PMID:25402154

  2. Dispersing Zwitterions into Comb Polymers for Nonviral Transfection: Experiments and Molecular Simulation.

    PubMed

    Ghobadi, Ahmadreza F; Letteri, Rachel; Parelkar, Sangram S; Zhao, Yue; Chan-Seng, Delphine; Emrick, Todd; Jayaraman, Arthi

    2016-02-01

    Polymer-based gene delivery vehicles benefit from the presence of hydrophilic groups that mitigate the inherent toxicity of polycations and that provide tunable polymer-DNA binding strength and stable complexes (polyplexes). However, hydrophilic groups screen charge, and as such can reduce cell uptake and transfection efficiency. We report the effect of embedding zwitterionic sulfobetaine (SB) groups in cationic comb polymers, using a combination of experiments and molecular simulations. Ring-opening metathesis polymerization (ROMP) produced comb polymers with tetralysine (K4) and SB pendent groups. Dynamic light scattering, zeta potential measurements, and fluorescence-based experiments, together with coarse-grained molecular dynamics simulations, described the effect of SB groups on the size, shape, surface charge, composition, and DNA binding strength of polyplexes formed using these comb polymers. Experiments and simulations showed that increasing SB composition in the comb polymers decreased polymer-DNA binding strength, while simulations indicated that the SB groups distributed throughout the polyplex. This allows polyplexes to maintain a positive surface charge and provide high levels of gene expression in live cells. Notably, comb polymers with nearly 50 mol % SB form polyplexes that exhibit positive surface charge similarly as polyplexes formed from purely cationic comb polymers, indicating the ability to introduce an appreciable amount of SB functionality without screening surface charge. This integrated simulation-experimental study demonstrates the effectiveness of incorporating zwitterions in polyplexes, while guiding the design of new and effective gene delivery vectors. PMID:26741292

  3. Frequency-noise measurements of optical frequency combs by multiple fringe-side discriminator.

    PubMed

    Coluccelli, Nicola; Cassinerio, Marco; Gambetta, Alessio; Laporta, Paolo; Galzerano, Gianluca

    2015-01-01

    The frequency noise of an optical frequency comb is routinely measured through the hetherodyne beat of one comb tooth against a stable continuous-wave laser. After frequency-to-voltage conversion, the beatnote is sent to a spectrum analyzer to retrive the power spectral density of the frequency noise. Because narrow-linewidth continuous-wave lasers are available only at certain wavelengths, heterodyning the comb tooth can be challenging. We present a new technique for direct characterization of the frequency noise of an optical frequency comb, requiring no supplementary reference lasers and easily applicable in all spectral regions from the terahertz to the ultraviolet. The technique is based on the combination of a low finesse Fabry-Perot resonator and the so-called "fringe-side locking" method, usually adopted to characterize the spectral purity of single-frequency lasers, here generalized to optical frequency combs. The effectiveness of this technique is demonstrated with an Er-fiber comb source across the wavelength range from 1 to 2 μm. PMID:26548900

  4. Frequency comb generation by CW laser injection into a quantum-dot mode-locked laser.

    PubMed

    Pinkert, T J; Salumbides, E J; Tahvili, M S; Ubachs, W; Bente, E A J M; Eikema, K S E

    2012-09-10

    We report on frequency comb generation at 1.5 μm by injection of a CW laser in a hybridly mode-locked InAs/InP two-section quantum-dot laser (HMLQDL). The generated comb has > 60 modes spaced by ∼ 4.5 GHz and a -20 dBc width of > 100 GHz (23 modes) at > 30 dB signal to background ratio. Comb generation was observed with the CW laser (red) detuned more than 20 nm outside the HMLQDL spectrum, spanning a large part of the gain spectrum of the quantum dot material. It is shown that the generated comb is fully coherent with the injected CW laser and RF frequency used to drive the hybrid mode-locking. This method of comb generation is of interest for the creation of small and robust frequency combs for use in optical frequency metrology, high-frequency (> 100 GHz) RF generation and telecommunication applications. PMID:23037259

  5. Coherent dual-comb spectroscopy at high signal-to-noise ratio

    SciTech Connect

    Coddington, I.; Swann, W. C.; Newbury, N. R.

    2010-10-15

    Two coherent frequency combs are used to measure the full complex response of a sample in a configuration analogous to a dispersive Fourier transform spectrometer, infrared time domain spectrometer, or a multiheterodyne laser spectrometer. This dual-comb spectrometer retains the frequency accuracy and resolution of the reference underlying the stabilized combs. We discuss the specific design of our coherent dual-comb spectrometer and demonstrate the potential of this technique by measuring the overtone vibration of hydrogen cyanide, centered at 194 THz (1545 nm). We measure the fully normalized, complex response of the gas over a 9 THz bandwidth at 220 MHz frequency resolution yielding 41,000 resolution elements. The average spectral signal-to-noise ratio (SNR) over the 9 THz bandwidth is 2500 for both the magnitude and phase of the measured spectral response and the peak SNR is 4000. This peak SNR corresponds to a fractional absorption sensitivity of 0.05% and a phase sensitivity of 250 microradians. As the spectral coverage of combs expands, coherent dual-comb spectroscopy could provide high-frequency accuracy and resolution measurements of a complex sample response across a range of spectral regions. Work of U. S. government, not subject to copyright.

  6. Modeling of a High Force Density Fishbone Shaped Electrostatic Comb Drive Microactuator

    PubMed Central

    Megat Hasnan, Megat Muhammad Ikhsan; Mohd Sabri, Mohd Faizul; Mohd Said, Suhana; Nik Ghazali, Nik Nazri

    2014-01-01

    This paper presents the design and evaluation of a high force density fishbone shaped electrostatic comb drive actuator. This comb drive actuator has a branched structure similar to a fishbone, which is intended to increase the capacitance of the electrodes and hence increase the electrostatic actuation force. Two-dimensional finite element analysis was used to simulate the motion of the fishbone shaped electrostatic comb drive actuator and compared against the performance of a straight sided electrostatic comb drive actuator. Performances of both designs are evaluated by comparison of displacement and electrostatic force. For both cases, the active area and the minimum gap distance between the two electrodes were constant. An active area of 800 × 300 μm, which contained 16 fingers of fishbone shaped actuators and 40 fingers of straight sided actuators, respectively, was used. Through simulation, improvement of drive force of the fishbone shaped electrostatic comb driver is approximately 485% higher than conventional electrostatic comb driver. These results indicate that the fishbone actuator design provides good potential for applications as high force density electrostatic microactuator in MEMS systems. PMID:25165751

  7. Frequency-noise measurements of optical frequency combs by multiple fringe-side discriminator

    PubMed Central

    Coluccelli, Nicola; Cassinerio, Marco; Gambetta, Alessio; Laporta, Paolo; Galzerano, Gianluca

    2015-01-01

    The frequency noise of an optical frequency comb is routinely measured through the hetherodyne beat of one comb tooth against a stable continuous-wave laser. After frequency-to-voltage conversion, the beatnote is sent to a spectrum analyzer to retrive the power spectral density of the frequency noise. Because narrow-linewidth continuous-wave lasers are available only at certain wavelengths, heterodyning the comb tooth can be challenging. We present a new technique for direct characterization of the frequency noise of an optical frequency comb, requiring no supplementary reference lasers and easily applicable in all spectral regions from the terahertz to the ultraviolet. The technique is based on the combination of a low finesse Fabry-Perot resonator and the so-called “fringe-side locking” method, usually adopted to characterize the spectral purity of single-frequency lasers, here generalized to optical frequency combs. The effectiveness of this technique is demonstrated with an Er-fiber comb source across the wavelength range from 1 to 2 μm. PMID:26548900

  8. Genomics of Sex and Sex Chromosomes

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Sex chromosomes are distinctive, not only because of their gender determining role, but also for genomic features that reflect their evolutionary history. The genomic sequences in the ancient sex chromosomes of humans and in the incipient sex chromosomes of medaka, stickleback, and papaya exhibit u...

  9. Precision spectroscopy with a frequency-comb-calibrated solar spectrograph

    NASA Astrophysics Data System (ADS)

    Doerr, H.-P.

    2015-06-01

    The measurement of the velocity field of the plasma at the solar surface is a standard diagnostic tool in observational solar physics. Detailed information about the energy transport as well as on the stratification of temperature, pressure and magnetic fields in the solar atmosphere are encoded in Doppler shifts and in the precise shape of the spectral lines. The available instruments deliver data of excellent quality and precision. However, absolute wavelength calibration in solar spectroscopy was so far mostly limited to indirect methods and in general suffers from large systematic uncertainties of the order of 100 m/s. During the course of this thesis, a novel wavelength calibration system based on a laser frequency comb was deployed to the solar Vacuum Tower Telescope (VTT), Tenerife, with the goal of enabling highly accurate solar wavelength measurements at the level of 1 m/s on an absolute scale. The frequency comb was developed in a collaboration between the Kiepenheuer-Institute for Solar Physics, Freiburg, Germany and the Max Planck Institute for Quantum Optics, Garching, Germany. The efforts cumulated in the new prototype instrument LARS (Lars is an Absolute Reference Spectrograph) for solar precision spectroscopy which is in preliminary scientific operation since~2013. The instrument is based on the high-resolution echelle spectrograph of the VTT for which feed optics based on single-mode optical fibres were developed for this project. The setup routinely achieves an absolute calibration accuracy of 60 cm/s and a repeatability of 2.5 cm/s. An unprecedented repeatability of only 0.32 cm/s could be demonstrated with a differential calibration scheme. In combination with the high spectral resolving power of the spectrograph of 7x10^5 and virtually absent internal scattered light, LARS provides a spectral purity and fidelity that previously was the domain of Fourier-transform spectrometers only. The instrument therefore provides unique capabilities for

  10. Highly precise stabilization of intracavity prism-based Er:fiber frequency comb using optical-microwave phase detector.

    PubMed

    Zhang, Shuangyou; Wu, Jiutao; Leng, Jianxiao; Lai, Shunnan; Zhao, Jianye

    2014-11-15

    In this Letter, we demonstrate a fully stabilized Er:fiber frequency comb by using a fiber-based, high-precision optical-microwave phase detector. To achieve high-precision and long-term phase locking of the repetition rate to a microwave reference, frequency control techniques (tuning pump power and cavity length) are combined together as its feedback. Since the pump power has been used for stabilization of the repetition rate, we introduce a pair of intracavity prisms as a regulator for carrier-envelope offset frequency, thereby phase locking one mode of the comb to the rubidium saturated absorption transition line. The stabilized comb performs the same high stability as the reference for the repetition rate and provides a residual frequency instability of 3.6×10(-13) for each comb mode. The demonstrated stabilization scheme could provide a high-precision comb for optical communication, direct frequency comb spectroscopy. PMID:25490492

  11. On-chip frequency comb generation at visible wavelengths via simultaneous second- and third-order optical nonlinearities.

    PubMed

    Miller, Steven; Luke, Kevin; Okawachi, Yoshitomo; Cardenas, Jaime; Gaeta, Alexander L; Lipson, Michal

    2014-11-01

    Microresonator-based frequency comb generation at or near visible wavelengths would enable applications in precise optical clocks, frequency metrology, and biomedical imaging. Comb generation in the visible has been limited by strong material dispersion and loss at short wavelengths, and only very narrowband comb generation has reached below 800 nm. We use the second-order optical nonlinearity in an integrated high-Q silicon nitride ring resonator cavity to convert a near-infrared frequency comb into the visible range. We simultaneously demonstrate parametric frequency comb generation in the near-infrared, second-harmonic generation, and sum-frequency generation. We measure 17 comb lines converted to visible wavelengths extending to 765 nm. PMID:25401803

  12. Mid-infrared frequency comb based on a quantum cascade laser.

    PubMed

    Hugi, Andreas; Villares, Gustavo; Blaser, Stéphane; Liu, H C; Faist, Jérôme

    2012-12-13

    Optical frequency combs act as rulers in the frequency domain and have opened new avenues in many fields such as fundamental time metrology, spectroscopy and frequency synthesis. In particular, spectroscopy by means of optical frequency combs has surpassed the precision and speed of Fourier spectrometers. Such a spectroscopy technique is especially relevant for the mid-infrared range, where the fundamental rotational-vibrational bands of most light molecules are found. Most mid-infrared comb sources are based on down-conversion of near-infrared, mode-locked, ultrafast lasers using nonlinear crystals. Their use in frequency comb spectroscopy applications has resulted in an unequalled combination of spectral coverage, resolution and sensitivity. Another means of comb generation is pumping an ultrahigh-quality factor microresonator with a continuous-wave laser. However, these combs depend on a chain of optical components, which limits their use. Therefore, to widen the spectroscopic applications of such mid-infrared combs, a more direct and compact generation scheme, using electrical injection, is preferable. Here we present a compact, broadband, semiconductor frequency comb generator that operates in the mid-infrared. We demonstrate that the modes of a continuous-wave, free-running, broadband quantum cascade laser are phase-locked. Combining mode proliferation based on four-wave mixing with gain provided by the quantum cascade laser leads to a phase relation similar to that of a frequency-modulated laser. The comb centre carrier wavelength is 7 micrometres. We identify a narrow drive current range with intermode beat linewidths narrower than 10 hertz. We find comb bandwidths of 4.4 per cent with an intermode stability of less than or equal to 200 hertz. The intermode beat can be varied over a frequency range of 65 kilohertz by radio-frequency injection. The large gain bandwidth and independent control over the carrier frequency offset and the mode spacing

  13. On the generation of octave-spanning optical frequency combs using monolithic whispering-gallery-mode microresonators.

    PubMed

    Chembo, Yanne K; Yu, Nan

    2010-08-15

    Octave-spanning optical frequency combs are especially interesting in optical metrology owing to the ability of self-referencing. We report a theoretical study on the generation of octave-spanning combs in the whispering gallery modes of a microresonator. Through a modal expansion model simulation in a calcium fluoride microcavity, we show that a combination of suitable pump power, Kerr nonlinearity, and dispersion profile can lead to stable and robust octave-spanning optical frequency combs. PMID:20717427

  14. Long-path atmospheric measurements using dual frequency comb measurements

    NASA Astrophysics Data System (ADS)

    Waxman, Eleanor; Cossel, Kevin; Truong, Gar-Wing; Giorgetta, Fabrizio; Swann, William; Coddington, Ian; Newbury, Nathan

    2016-04-01

    The dual frequency comb spectrometer is a new tool for performing atmospheric trace gas measurements. This instrument is capable of measuring carbon dioxide, methane, and water with extremely high resolution in the region between 1.5 and 2.1 microns in the near-IR. It combines the high resolution of a laboratory-based FTIR instrument with the portability of a long-path DOAS system. We operate this instrument at path lengths of a few kilometers, thus bridging the spatial resolution of in-situ point sensors and the tens of square kilometer footprints of satellites. This spatial resolution is ideal for measuring greenhouse gas emissions from cities. Here we present initial long-path integrated column measurements of the greenhouse gases water, carbon dioxide, and methane in an urban environment. We present a time series with 5 minute time resolution over a 2 kilometer path in Boulder, Colorado at the urban-rural interface. We validate this data via a comparison with an in-situ greenhouse gas monitor co-located along the measurement path and show that we agree well on the baseline concentration but that we are significantly less sensitive to local point source emission that have high temporal variability, making this instrument ideal for measurements of average city-wide emissions. We additionally present progress towards measurements over an 11 kilometer path over downtown Boulder to measure the diurnal flux of greenhouse gases across the city.

  15. Berry phase oscillations in a one-dimensional Dirac comb

    NASA Astrophysics Data System (ADS)

    Hodge, William; Cassera, Nicholas; Rave, Matthew

    In quantum mechanics, the Berry phase is a geometric phase acquired by a wave function over the course of a cycle, when subjected to adiabatic processes. In general, this phase is due to the geometry of the underlying parameter space and thus depends only on the path taken. In any system described by a periodic potential, the torus topology of the Brillouin zone itself can lead to such a phase. In this work, we numerically calculate the Berry phase for a one-dimensional Dirac comb described by N distinct wells per unit cell. As expected, the resulting Berry phase exhibits a rich band-dependence. In the case where N = 2 , we find that the Berry phase corresponding to the nth energy band oscillates such that γn (x) =An sin (πx) cos [ (2 n - 1) πx ] , where An is a band-dependent constant and 0 < x < 1 is the relative position of the two wells. This expression, obtained using perturbation theory, gives excellent agreement with exact numerical results, even at low energy levels. The Berry phase exhibits a similar behavior for cases where N > 2 .

  16. The Assembly of Nanorods in Comb Polymer Supramolecules

    NASA Astrophysics Data System (ADS)

    Mastroianni, Alexander; Thorkelsson, Kari; Luther, Joseph; Alivisatos, Paul; Xu, Ting

    2010-03-01

    Inorganic nanoparticles exhibit a wide range of size-dependent properties and present great promise in technological applications. Fully harnessing this potential requires developing bottom-up strategies to assemble nanoparticles over multiple length scales simultaneously. Nanoparticles have been co-assembled with block copolymers (BCPs). Often this approach requires delicate balance between particle-polymer interactions and entropic penalty associated with polymer chain deformation upon particle incorporation. Recently, we showed that a coil-comb supramolecule formed by non- covalent attachment of small molecule amphiphiles to one block of a BCP can be used to direct nanoparticle assemblies with high precision. The alkyl tail of the small molecules chosen interacts favorably with the native alkyl ligands of a wide variety of inorganic nanoparticles and eliminates the need for particle surface modification. Upon attaching small molecule to one BCP block, the polymer chain stiffens, providing entropic driving force to further direct nanoparticle organization within BCP microdomains. Here, the co-assembly of these supramolecules with nanorods was systematically investigated as a function of small molecule loading, supramolecular morphology, nanorod diameter, and aspect ratio. The presented fundamental studies pave a path toward nanorod-based device fabrication.

  17. The Comb Jelly Opsins and the Origins of Animal Phototransduction

    PubMed Central

    Feuda, Roberto; Rota-Stabelli, Omar; Oakley, Todd H.; Pisani, Davide

    2014-01-01

    Opsins mediate light detection in most animals, and understanding their evolution is key to clarify the origin of vision. Despite the public availability of a substantial collection of well-characterized opsins, early opsin evolution has yet to be fully understood, in large part because of the high level of divergence observed among opsins belonging to different subfamilies. As a result, different studies have investigated deep opsin evolution using alternative data sets and reached contradictory results. Here, we integrated the data and methods of three, key, recent studies to further clarify opsin evolution. We show that the opsin relationships are sensitive to outgroup choice; we generate new support for the existence of Rhabdomeric opsins in Cnidaria (e.g., corals and jellyfishes) and show that all comb jelly opsins belong to well-recognized opsin groups (the Go-coupled opsins or the Ciliary opsins), which are also known in Bilateria (e.g., humans, fruit flies, snails, and their allies) and Cnidaria. Our results are most parsimoniously interpreted assuming a traditional animal phylogeny where Ctenophora are not the sister group of all the other animals. PMID:25062921

  18. The comb jelly opsins and the origins of animal phototransduction.

    PubMed

    Feuda, Roberto; Rota-Stabelli, Omar; Oakley, Todd H; Pisani, Davide

    2014-08-01

    Opsins mediate light detection in most animals, and understanding their evolution is key to clarify the origin of vision. Despite the public availability of a substantial collection of well-characterized opsins, early opsin evolution has yet to be fully understood, in large part because of the high level of divergence observed among opsins belonging to different subfamilies. As a result, different studies have investigated deep opsin evolution using alternative data sets and reached contradictory results. Here, we integrated the data and methods of three, key, recent studies to further clarify opsin evolution. We show that the opsin relationships are sensitive to outgroup choice; we generate new support for the existence of Rhabdomeric opsins in Cnidaria (e.g., corals and jellyfishes) and show that all comb jelly opsins belong to well-recognized opsin groups (the Go-coupled opsins or the Ciliary opsins), which are also known in Bilateria (e.g., humans, fruit flies, snails, and their allies) and Cnidaria. Our results are most parsimoniously interpreted assuming a traditional animal phylogeny where Ctenophora are not the sister group of all the other animals. PMID:25062921

  19. Dual-etalon, cavity-ring-down, frequency comb spectroscopy.

    SciTech Connect

    Strecker, Kevin E.; Chandler, David W.

    2010-10-01

    The 'dual etalon frequency comb spectrometer' is a novel low cost spectometer with limited moving parts. A broad band light source (pulsed laser, LED, lamp ...) is split into two beam paths. One travels through an etalon and a sample gas, while the second arm is just an etalon cavity, and the two beams are recombined onto a single detector. If the free spectral ranges (FSR) of the two cavities are not identical, the intensity pattern at the detector with consist of a series of heterodyne frequencies. Each mode out of the sample arm etalon with have a unique frequency in RF (radio-frequency) range, where modern electronics can easily record the signals. By monitoring these RF beat frequencies we can then determine when an optical frequencies is absorbed. The resolution is set by the FSR of the cavity, typically 10 MHz, with a bandwidth up to 100s of cm{sup -1}. In this report, the new spectrometer is described in detail and demonstration experiments on Iodine absorption are carried out. Further we discuss powerful potential next generation steps to developing this into a point sensor for monitoring combustion by-products, environmental pollutants, and warfare agents.

  20. Broadband Spectroscopy with Dual Combs and Cavity Enhancement

    NASA Astrophysics Data System (ADS)

    Holzwarth, Ronald; Bernhardt, Birgitta; Ozawa, Akira; Udem, Thomas; Hänsch, Theodor W.; Jacquet, Patrick; Jacquey, Marion; Guelachvili, Guy; Kobayashi, Yohei; Picque, Nathalie

    2010-06-01

    Classical FTIRs handle the task of massively parallel spectroscopic probing by interferometric detection. In contrast a frequency comb Fourier transform spectrometer (FC-FTS) retains the principle of combining two interferometer beams but uses two inputs from two independent sources. Thus we can offset their frequencies to facilitate multifrequency heterodyne signal processing. The advantages of this spectrometer compared with the classical FTIR include ease of operation (no cumbersome moving delay lines), speed of acquisition (18 μs demonstrated), collimated long-distance propagation, possibly diffraction-limited microscopic probing, and mid infrared as well as THz operation if necessary. In a recent proof of principle experiment we have dramatically improved the sensitivity by the implementation of an enhancement cavity around the probing volume We recorded, within 18 μs, spectra of the ammonia 1.0 μm overtone bands comprising 1500 spectral elements and spanning 20 nm with 4.5 GHz resolution and a noise-equivalent-absorption at one-second-averaging of 1 10-10 cm-1Hz-1/2, thus opening a route to time-resolved spectroscopy of rapidly-evolving single-events. Since FC-FTS only needs one detector that is easily available in practically all spectral regions, it can be envisioned that cavity-enhanced FC-FTS will assume a position of dominance for the measurements of real-time ultra-sensitive spectra in the molecular fingerprint region. B. Bernhardt et. al., Nature Photonics, 4 (55), January 2010.

  1. Reclassification of Acetomicrobium faecale as Caldicoprobacter faecalis comb. nov.

    PubMed

    Bouanane-Darenfed, Amel; Ben Hania, Wajdi; Cayol, Jean-Luc; Ollivier, Bernard; Fardeau, Marie-Laure

    2015-10-01

    Taking into account its phenotypical and genetic characteristics, Acetomicrobium faecale was first recognized as a member of the genus Acetomicrobium, family Bacteroidaceae, order Bacteroidales, phylum Bacteroidetes, with Acetomicrobium flavidum the type species of the genus. However, it was found that A. faecale had 95.8 %, 97.6 % and 98.4 % similarity, respectively, with Caldicoprobacter guelmensis, Caldicoprobacter algeriensis and Caldicoprobacter oshimai and only 82 % similarity with A. flavidum. The DNA G+C content of A. faecale is 45 mol , which is of the same order as the DNA G+C content of the three strains of species of the genus Caldicoprobacter and its main fatty acid is C16 : 0, with its second most prominent fatty acid, iso-C17 : 0, also common to strains of species of the genus Caldicoprobacter. On the basis of further phylogenetic, genetic and chemotaxonomic studies, we propose that A. faecale (type strain DSM 20678T = JCM 30420T) be reclassified as Caldicoprobacter faecalis comb. nov. PMID:26297233

  2. Brillouin Stokes comb generated in a distributed fiber Raman amplifier

    NASA Astrophysics Data System (ADS)

    Martins, Hugo F.; Marques, Manuel B.; Frazão, Orlando

    2011-05-01

    A Brillouin Stokes comb laser with increased flatness is reported. The feedback for the laser is provided by a distributed mirror combined with a narrowband seed laser. The Brillouin seed power and wavelength optimization is crucial in order to obtain a uniform power level between Stokes lines. The Brillouin seed must have a relatively large power and its wavelength must be located close to the Raman peak gain region. The flat-amplitude bandwidth is also determined by the choice of Raman pump wavelength. A flat-amplitude bandwidth of 34 nm from 1538 nm to 1572 nm is measured when Raman pump wavelength is set to 1455 nm. 425 uniform Brillouin Stokes lines with 0.08 nm spacing are generated across the wavelength range. The average signal-to-noise ratio of 15 dB is obtained for all the Brillouin Stokes lines. This type of laser can be used in optical communications as a multiwavelength source and also in metrology as a frequency ruler.

  3. The Riddle of Sex.

    ERIC Educational Resources Information Center

    Sagan, Dorion; Margulis, Lynn

    1985-01-01

    Discusses the work of evolutionary biologists in determining how sexual reproduction arose. Topics explored include the nature of sex, bacterial sex, meiotic sex, and asexual reproduction. A diagram (which can be used as a duplicating master) illustrating types of bacterial sex is included. (DH)

  4. Regeneration of ciliary comb plates in the ctenophore Mnemiopsis leidyi. i. morphology.

    PubMed

    Tamm, Sidney L

    2012-01-01

    Regeneration of missing body parts in model organisms provides information on the mechanisms underlying the regeneration process. The aim here is to use ctenophores to investigate regeneration of their giant ciliary swimming plates. When part of a row of comb plates on Mnemiopsis is excised, the wound closes and heals, greatly increasing the distance between comb plates near the former cut edges. Video differential interference contrast (DIC) microscopy of the regeneration of new comb plates between widely separated plates shows localized widenings of the interplate ciliated groove (ICG) first, followed by growth of two opposing groups of comb plate cilia on either side. The split parts of a new plate elongate as their bases extend laterally away from the ICG widening and continue ciliogenesis at both ends. The split parts of a new plate grow longer and move closer together into the ICG widening until they merge into a single plate that interrupts the ICG in a normal manner. Video DIC snapshots of dissected gap preparations 1.5-3-day postoperation show that ICG widenings and/or new plates do not all appear at the same time or with uniform spacing within a gap: the lengths and distances between young plates in a gap are quite variable. Video stereo microscopy of intact animals 3-4 days after the operation show that all the new plates that will form in a gap are present, fairly evenly spaced and similar in length, but smaller and closer together than normal. Normal development of comb plates in embryos and growing animals is compared to the pattern of comb plate regeneration in adults. Comb plate regeneration differs in the cydippid Pleurobrachia that lacks ICGs and has a firmer mesoglea than Mnemiopsis. This study provides a morphological foundation for histological, cellular, and molecular analysis of ciliary regeneration in ctenophores. PMID:21987455

  5. Plastic detection comb better than visual screening for diagnosis of head louse infestation.

    PubMed

    Balcioglu, C; Burgess, I F; Limoncu, M E; Sahin, M T; Ozbel, Y; Bilaç, C; Kurt, O; Larsen, K S

    2008-10-01

    Finding lice can be difficult in head louse infestation. We compared a new louse detection comb with visual inspection. All children in two rural Turkish schools were screened by the two methods. Those with lice were offered treatment and the results monitored by detection combing. Children with nits only were re-screened to identify latent infestations. Using visual inspection we found 214/461 children (46%) with nits but only 30 (6.5%) with live lice. In contrast detection combing found 96 (21%) with live lice, of whom 20 had no nits. Detection combing was 3.84 times more effective than visual inspection for finding live lice. Only 10/138 (7.2%) children with nits and no lice were found to have active infestation by day 16. We found that the detection comb is significantly (P<0.001) more effective than visual screening for diagnosis; that nits are not a good indicator of active infestation; and that treatment with 1% permethrin was 89.6% effective. PMID:18177517

  6. Highly Stable, Anion Conductive, Comb-Shaped Copolymers for Alkaline Fuel Cells

    SciTech Connect

    Li, NW; Leng, YJ; Hickner, MA; Wang, CY

    2013-07-10

    To produce an anion-conductive and durable polymer electrolyte for alkaline fuel cell applications, a series of quaternized poly(2,6-dimethyl phenylene oxide)s containing long alkyl side chains pendant to the nitrogen-centered cation were synthesized using a Menshutkin reaction to form comb-shaped structures. The pendant alkyl chains were responsible for the development of highly conductive ionic domains, as confirmed by small-angle X-ray scattering (SAXS). The comb-shaped polymers having one alkyl side chain showed higher hydroxide conductivities than those with benzyltrimethyl ammonium moieties or structures with more than one alkyl side chain per cationic site. The highest conductivity was observed for comb-shaped polymers with benzyldimethylhexadecyl ammonium cations. The chemical stabilities of the comb-shaped membranes were evaluated under severe, accelerated-aging conditions, and degradation was observed by measuring IEC and ion conductivity changes during aging. The comb-shaped membranes retained their high ion conductivity in 1 M NaOH at 80 degrees C for 2000 h. These cationic polymers were employed as ionomers in catalyst layers for alkaline fuel cells. The results indicated that the C-16 alkyl side chain ionomer had a slightly better initial performance, despite its low IEC value, but very poor durability in the fuel cell. In contrast, 90% of the initial performance was retained for the alkaline fuel cell with electrodes containing the C-6 side chain after 60 h of fuel cell operation.

  7. A novel vertical comb-drive electrostatic actuator using a one layer process

    NASA Astrophysics Data System (ADS)

    Hailu, Zewdu; He, Siyuan; Ben Mrad, Ridha

    2014-11-01

    This paper presents the design, fabrication and testing of a new residual stress gradient based vertical comb-drive actuator. Conventional vertical comb-drive actuators need two structural layers, i.e. one for the moving fingers and a second for the fixed fingers. A vertical comb-drive actuator based on a single structural layer micromachining process, using the residual stress gradient along the thickness of the nickel of the MetalMUMPs (Metal Multi-User MEMS process) fabrication process, is developed. The MetalMUMPs provides a 20 μm thick nickel film and is subject to residual stress gradients along its thickness. Two curve-up beams are devised to curve out of plane after release. The curve-up beams raise a plate with comb fingers above the substrate to form the moving fingers. The fixed comb fingers are connected to the substrate via anchors. When a voltage is applied across the moving and the fixed fingers, the moving fingers move down towards the fixed fingers. Experimental measurements on prototypes have verified the design principle. A vertical displacement of 4.81 µm at 150 V was measured.

  8. Microwave and RF applications for micro-resonator based frequency combs

    NASA Astrophysics Data System (ADS)

    Nguyen, Thach G.; Shoeiby, Mehrdad; Ferrera, Marcello; Pasquazi, Alessia; Peccianti, Marco; Chu, Sai T.; Little, Brent E.; Morandotti, Roberto; Mitchell, Arnan; Moss, David J.

    2016-02-01

    Photonic integrated circuits that exploit nonlinear optics in order to generate and process signals all-optically have achieved performance far superior to that possible electronically - particularly with respect to speed. We review the recent achievements based in new CMOS-compatible platforms that are better suited than SOI for nonlinear optics, focusing on radio frequency (RF) and microwave based applications that exploit micro-resonator based frequency combs. We highlight their potential as well as the challenges to achieving practical solutions for many key applications. These material systems have opened up many new capabilities such as on-chip optical frequency comb generation and ultrafast optical pulse generation and measurement. We review recent work on a photonic RF Hilbert transformer for broadband microwave in-phase and quadrature-phase generation based on an integrated frequency optical comb. The comb is generated using a nonlinear microring resonator based on a CMOS compatible, high-index contrast, doped-silica glass platform. The high quality and large frequency spacing of the comb enables filters with up to 20 taps, allowing us to demonstrate a quadrature filter with more than a 5-octave (3 dB) bandwidth and an almost uniform phase response.

  9. Comb-branched Polymer Electrolytes: Architectural Changes That Promote Increased Li^+ Transport

    NASA Astrophysics Data System (ADS)

    Demille, Robert; Murthy, Sowmya; Bedrov, Dmitry; Smith, Grant

    2012-02-01

    The use of solid polymer electrolytes (SPEs) in the batteries of next generation technology applications is promising due to their safety and stability, yet is also hindered by low conductivity and high temperature requirements. Recent simulations of comb-branched poly(epoxide ether)-based SPEs have shown the comb-branched architecture to be able to overcome some of these hindrances. While providing the advantage of preventing crystallinity and allowing the optimization of the backbone to be decoupled from that of the side chain, the comb-branched SPE studied suffers from slow Li^+ cation dynamics due to coordination with the backbone. To improve Li^+ transport, we have modified the architecture of the comb-branched poly(epoxide ether) by attaching the side chains to the backbone with non-coordinating, flexible spacers. Inclusion of these spacers has resulted in a five-fold increase in the diffusion of Li^+ cation effected through 1) an increased side chain flexibility, 2) a decreased interaction of the cation with the dynamically slow backbone, and 3) quick conformational dynamics of the entire side chain. Additionally we report on other desirable architectural changes, such as including carbonate solvating moieties, to comb-branched SPEs allowing enhanced mobility of Li^+.

  10. Ultra broadband microwave frequency combs generated by an optical pulse-injected semiconductor laser.

    PubMed

    Juan, Yu-Shan; Lin, Fan-Yi

    2009-10-12

    We have demonstrated and characterized the generation of ultra broadband microwave frequency combs with an optical pulse-injected semiconductor laser. Through optical pulse injection, the microwave frequency combs generated in the slave laser (SL) have bandwidths greater than 20 GHz within a +/-5 dB amplitude variation, which is almost 3-fold of the 7 GHz relaxation oscillation frequency of the laser used. The line spacing of the comb is tunable from 990 MHz to 2.6 GHz, determined by the repetition frequency of the injection optical pulses produced by the master laser (ML) with optoelectronic feedback. At an offset frequency of 200 kHz, a single sideband (SSB) phase noise of -60 dBc/kHz (-90 dBc/Hz estimated) in the 1(st) harmonic is measured while a noise suppression relative to the injected regular pulsing state of the ML of more than 25 dB in the 17(th) harmonic is achieved. A pulsewidth of 29 ps and a ms timing jitter of 18.7 ps are obtained in the time domain for the microwave frequency comb generated. Further stabilization is realized by modulating the ML at the fundamental frequency of the injected regular pulsing state. The feasibility of utilizing the generated microwave frequency comb in frequency conversion and signal broadcasting is also explored. The conversion gain of each channel increases linearly as the signal power increases with a ratio of about 0.81 dB/dBm. PMID:20372590

  11. Cutaneous hyalohyphomycosis due to Parengyodontium album gen. et comb. nov.

    PubMed

    Tsang, Chi-Ching; Chan, Jasper F W; Pong, Wai-Mei; Chen, Jonathan H K; Ngan, Antonio H Y; Cheung, Mei; Lai, Christopher K C; Tsang, Dominic N C; Lau, Susanna K P; Woo, Patrick C Y

    2016-10-01

    "Engyodontium album" is an environmental saprobic mould and an emerging opportunistic pathogen able to cause both superficial and systemic infections. In this study, we isolated a mould from the skin lesion biopsy specimen of the right shin in a patient who received renal transplantation for end-stage renal failure with prednisolone, tacrolimus, and azathioprine immunosuppressant therapy. Histology of the skin biopsy showed mild squamous hyperplasia and neutrophilic infiltrate in the epidermis, active chronic inflammation in the dermis, and fat necrosis in the subcutis, with numerous fungal elements within the serum crusts. On Sabouraud glucose agar, the fungus grew as white, cobweb-like, floccose colonies. Microscopically, conidiogenous cells were arranged in whorls of one to seven at wide angles, with zigzag-shaped terminal fertile regions and smooth, hyaline, oval, apiculate conidia. DNA sequencing showed the mould isolate belonged to "E. album" but matrix-assisted laser desorption ionisation-time of flight mass spectrometry (MALDI-TOF MS) failed to identify the isolate. Phylogenetic analyses based on the internal transcribed spacer region, 28S nuclear ribosomal DNA, and β-tubulin gene and MALDI-TOF MS coupled with hierarchical cluster analysis showed that "E. album" is distantly related to other Engyodontium species and should be transferred to a novel genus within the family Cordycipitaceae, for which the name Parengyodontium album gen. et comb. nov. is proposed. Three potential cryptic species within this species complex were also revealed. Antifungal susceptibility testing showed posaconazole and voriconazole had high activities against all clinical P. album isolates and may be better drug options for treating P. album infections. PMID:27161787

  12. Biased diffusion in three-dimensional comb-like structures

    NASA Astrophysics Data System (ADS)

    Berezhkovskii, Alexander M.; Dagdug, Leonardo; Bezrukov, Sergey M.

    2015-04-01

    In this paper, we study biased diffusion of point Brownian particles in a three-dimensional comb-like structure formed by a main cylindrical tube with identical periodic cylindrical dead ends. It is assumed that the dead ends are thin cylinders whose radius is much smaller than both the radius of the main tube and the distance between neighboring dead ends. It is also assumed that in the main tube, the particle, in addition to its regular diffusion, moves with a uniform constant drift velocity. For such a system, we develop a formalism that allows us to derive analytical expressions for the Laplace transforms of the first two moments of the particle displacement along the main tube axis. Inverting these Laplace transforms numerically, one can find the time dependences of the two moments for arbitrary values of both the drift velocity and the dead-end length, including the limiting case of infinitely long dead ends, where the unbiased diffusion becomes anomalous at sufficiently long times. The expressions for the Laplace transforms are used to find the effective drift velocity and diffusivity of the particle as functions of its drift velocity in the main tube and the tube geometric parameters. As might be expected from common-sense arguments, the effective drift velocity monotonically decreases from the initial drift velocity to zero as the dead-end length increases from zero to infinity. The effective diffusivity is a more complex, non-monotonic function of the dead-end length. As this length increases from zero to infinity, the effective diffusivity first decreases, reaches a minimum, and then increases approaching a plateau value which is proportional to the square of the particle drift velocity in the main tube.

  13. Mechanisms behind the metabolic flexibility of an invasive comb jelly

    NASA Astrophysics Data System (ADS)

    Augustine, Starrlight; Jaspers, Cornelia; Kooijman, Sebastiaan A. L. M.; Carlotti, François; Poggiale, Jean-Christophe; Freitas, Vânia; van der Veer, Henk; van Walraven, Lodewijk

    2014-11-01

    Mnemiopsis leidyi is an invasive comb jelly which has successfully established itself in European seas. The species is known to produce spectacular blooms yet it is holoplanktonic and not much is known about its population dynamics in between. One way to gain insight on how M. leidyi might survive between blooms and how it can bloom so fast is to study how the metabolism of this species actually responds to environmental changes in food and temperature over its different life-stages. To this end we combined modelling and data analysis to study the energy budget of M. leidyi over its full life-cycle using Dynamic Energy Budget (DEB) theory and literature data. An analysis of data obtained at temperatures ranging from 8 to 30 °C suggests that the optimum thermal tolerance range of M. leidyi is higher than 12 °C. Furthermore M. leidyi seems to undergo a so-called metabolic acceleration after hatching. Intriguingly, the onset of the acceleration appears to be delayed and the data do not yet exist which allows determining what actually triggers it. It is hypothesised that this delay confers a lot of metabolic flexibility by controlling generation time. We compared the DEB model parameters for this species with those of another holoplanktonic gelatinous zooplankton species (Pelagia noctiluca). After accounting for differences in water content, the comparison shows just how fundamentally different the two energy allocation strategies are. P. noctiluca has an extremely high reserve capacity, low turnover times of reserve compounds and high resistance to shrinking. M. leidyi adopts the opposite strategy: it has a low reserve capacity, high turnover rates of reserve compounds and fast shrinking.

  14. Mode-locked dark pulse Kerr combs in normal-dispersion microresonators

    NASA Astrophysics Data System (ADS)

    Xue, Xiaoxiao; Xuan, Yi; Liu, Yang; Wang, Pei-Hsun; Chen, Steven; Wang, Jian; Leaird, Dan E.; Qi, Minghao; Weiner, Andrew M.

    2015-09-01

    The generation of Kerr frequency combs in a coherently driven nonlinear microresonator is now extensively investigated more generally by the research community as a potentially portable technology for a variety of applications. Here, we report experiments in which dark pulse combs are formed in normal-dispersion microresonators with mode-interaction-assisted excitation, and mode-locking transitions are observed in the normal-dispersion regime. The mode-interaction-aided excitation of dark pulses appears to occur through a deterministic pathway, in sharp contrast to the situation for bright pulses in the anomalous dispersion region. The ability to mode-lock in the normal-dispersion regime increases the freedom in the microresonator design and may make it possible to extend Kerr comb generation into the visible, where material dispersion is likely to dominate.

  15. Doppler cooling with coherent trains of laser pulses and a tunable velocity comb

    SciTech Connect

    Ilinova, Ekaterina; Ahmad, Mahmoud; Derevianko, Andrei

    2011-09-15

    We explore the possibility of decelerating and Doppler cooling an ensemble of two-level atoms by a coherent train of short, nonoverlapping laser pulses. We derive analytical expressions for mechanical force exerted by the train. In frequency space the force pattern reflects the underlying frequency comb structure. The pattern depends strongly on the ratio of the atomic lifetime to the repetition time between the pulses and pulse area. For example, in the limit of short lifetimes, the frequency-space peaks of the optical force wash out. We propose to tune the carrier-envelope offset frequency to follow the Doppler-shifted detuning as atoms decelerate; this leads to compression of atomic velocity distribution about comb teeth and results in a ''velocity comb''--a series of narrow equidistant peaks in the velocity space.

  16. Molecular Combing of Single DNA Molecules on the 10 Megabase Scale

    PubMed Central

    Kaykov, Atanas; Taillefumier, Thibaud; Bensimon, Aaron; Nurse, Paul

    2016-01-01

    DNA combing allows the investigation of DNA replication on genomic single DNA molecules, but the lengths that can be analysed have been restricted to molecules of 200–500 kb. We have improved the DNA combing procedure so that DNA molecules can be analysed up to the length of entire chromosomes in fission yeast and up to 12 Mb fragments in human cells. Combing multi-Mb-scale DNA molecules revealed previously undetected origin clusters in fission yeast and shows that in human cells replication origins fire stochastically forming clusters of fired origins with an average size of 370 kb. We estimate that a single human cell forms around 3200 clusters at mid S-phase and fires approximately 100,000 origins to complete genome duplication. The procedure presented here will be adaptable to other organisms and experimental conditions. PMID:26781994

  17. Dual optical frequency comb architecture with capabilities from visible to mid-infrared.

    PubMed

    Jerez, Borja; Martín-Mateos, Pedro; Prior, Estefanía; de Dios, Cristina; Acedo, Pablo

    2016-06-27

    In this paper, a new approach to dual comb generation based on well-known optical techniques (Gain-Switching and Optical Injection Locking) is presented. The architecture can be implemented using virtually every kind of continuous-wave semiconductor laser source (DFB, VCSEL, QCL) and without the necessity of electro-optic modulators. This way, a frequency-agile and adaptive dual-comb architecture is provided with potential implementation capabilities from mid-infrared to near ultraviolet. With a RF comb comprising around 70 teeth, the system is validated in the 1.5 μm region measuring the absorption feature of H13CN at 1538.523 nm with a minimum integration time of 10 μs. PMID:27410649

  18. Comb-based radiofrequency photonic filters with rapid tunability and high selectivity

    NASA Astrophysics Data System (ADS)

    Supradeepa, V. R.; Long, Christopher M.; Wu, Rui; Ferdous, Fahmida; Hamidi, Ehsan; Leaird, Daniel E.; Weiner, Andrew M.

    2012-03-01

    Photonic technologies have received considerable attention regarding the enhancement of radiofrequency electrical systems, including high-frequency analogue signal transmission, control of phased arrays, analog-to-digital conversion and signal processing. Although the potential of radiofrequency photonics for the implementation of tunable electrical filters over broad radiofrequency bandwidths has been much discussed, the realization of programmable filters with highly selective filter lineshapes and rapid reconfigurability has faced significant challenges. A new approach for radiofrequency photonic filters based on frequency combs offers a potential route to simultaneous high stopband attenuation, fast tunability and bandwidth reconfiguration. In one configuration, tuning of the radiofrequency passband frequency is demonstrated with unprecedented (~40 ns) speed by controlling the optical delay between combs. In a second, fixed filter configuration, cascaded four-wave mixing simultaneously broadens and smoothes the comb spectra, resulting in Gaussian radiofrequency filter lineshapes exhibiting an extremely high (>60 dB) main lobe to sidelobe suppression ratio and (>70 dB) stopband attenuation.

  19. Solar radial velocity variations and the search for Venus enabled by a laser frequency comb

    NASA Astrophysics Data System (ADS)

    Phillips, David F.; Dumusque, Xavier; Li, Chih-Hao; Glenday, Alexander; Sasselov, Dimitar; Szentgyorgyi, Andrew; Walsworth, Ronald L.

    2016-05-01

    We have recently demonstrated 50 cm/s sensitivity in measuring the radial velocity (RV) between the Earth and Sun using a simple, compact solar telescope feeding the HARPS-N spectrograph at the Italian National Telescope calibrated with our green astro-comb. The green astro-comb is a laser frequency comb optimized for calibrating astrophysical spectrographs. We have been operating the solar telescope to detect the RV signal of the Sun as a star for the past year both to study RV jitter associated with stellar (solar) fluctuations and to demonstrate sensitivity of these instruments to detect terrestrial exoplanets. In this talk I will present results from calibrating the HARPS-N exoplanet searcher spectrograph, solar RV stability, and the current status of our search for the signature of Venus.

  20. A Precision Radial Velocity Pathfinder Instrument in the H Band with a Laser Frequency Comb

    NASA Astrophysics Data System (ADS)

    Terrien, Ryan; Mahadevan, S.; Ramsey, L.; Bender, C.; Redman, S.; Osterman, S.; Diddams, S.; Ycas, G.; Quinlan, F.; Botzer, B.

    2011-01-01

    We describe changes to the warm-bench, fiber-fed, Penn State Pathfinder instrument that enabled us to test the ability to recover precision radial velocities in the H-band. The use of thermal blocking filters that cut off at 1.7 microns allows us to observe in the H-band by blocking the overwhelming thermal flux beyond 2 microns. A PK-50 window provides further suppression of this thermal flux. We also describe the observations, reduction, and results from an August 2010 test run of this instrument with a 25 GHz NIST laser frequency comb calibration system. We obtained radial velocities of several bright stars with on-sky observation with the laser comb. Our results demonstrate the potential of our testbed configuration for obtaining precision radial velocities in the NIR, as well as the utility of laser frequency combs as wavelength calibrators in this wavelength regime.

  1. Dissemination of optical-comb-based ultra-broadband frequency reference through a fiber network.

    PubMed

    Nagano, Shigeo; Kumagai, Motohiro; Li, Ying; Ido, Tetsuya; Ishii, Shoken; Mizutani, Kohei; Aoki, Makoto; Otsuka, Ryohei; Hanado, Yuko

    2016-08-22

    We disseminated an ultra-broadband optical frequency reference based on a femtosecond (fs)-laser optical comb through a kilometer-scale fiber link. Its spectrum ranged from 1160 nm to 2180 nm without additional fs-laser combs at the end of the link. By employing a fiber-induced phase noise cancellation technique, the linewidth and fractional frequency instability attained for all disseminated comb modes were of order 1 Hz and 10-18 in a 5000 s averaging time. The ultra-broad optical frequency reference, for which absolute frequency is traceable to Japan Standard Time, was applied in the frequency stabilization of an injection-seeded Q-switched 2051 nm pulse laser for a coherent light detection and ranging LIDAR system. PMID:27557196

  2. Mach-zehnder based optical marker/comb generator for streak camera calibration

    SciTech Connect

    Miller, Edward Kirk

    2015-03-03

    This disclosure is directed to a method and apparatus for generating marker and comb indicia in an optical environment using a Mach-Zehnder (M-Z) modulator. High speed recording devices are configured to record image or other data defining a high speed event. To calibrate and establish time reference, the markers or combs are indicia which serve as timing pulses (markers) or a constant-frequency train of optical pulses (comb) to be imaged on a streak camera for accurate time based calibration and time reference. The system includes a camera, an optic signal generator which provides an optic signal to an M-Z modulator and biasing and modulation signal generators configured to provide input to the M-Z modulator. An optical reference signal is provided to the M-Z modulator. The M-Z modulator modulates the reference signal to a higher frequency optical signal which is output through a fiber coupled link to the streak camera.

  3. Fast wavelength calibration method for spectrometers based on waveguide comb optical filter

    SciTech Connect

    Yu, Zhengang; Huang, Meizhen Zou, Ye; Wang, Yang; Sun, Zhenhua; Cao, Zhuangqi

    2015-04-15

    A novel fast wavelength calibration method for spectrometers based on a standard spectrometer and a double metal-cladding waveguide comb optical filter (WCOF) is proposed and demonstrated. By using the WCOF device, a wide-spectrum beam is comb-filtered, which is very suitable for spectrometer wavelength calibration. The influence of waveguide filter’s structural parameters and the beam incident angle on the comb absorption peaks’ wavelength and its bandwidth are also discussed. The verification experiments were carried out in the wavelength range of 200–1100 nm with satisfactory results. Comparing with the traditional wavelength calibration method based on discrete sparse atomic emission or absorption lines, the new method has some advantages: sufficient calibration data, high accuracy, short calibration time, fit for produce process, stability, etc.

  4. Comb-calibrated frequency-modulated continuous-wave ladar for absolute distance measurements.

    PubMed

    Baumann, Esther; Giorgetta, Fabrizio R; Coddington, Ian; Sinclair, Laura C; Knabe, Kevin; Swann, William C; Newbury, Nathan R

    2013-06-15

    We demonstrate a comb-calibrated frequency-modulated continuous-wave laser detection and ranging (FMCW ladar) system for absolute distance measurements. The FMCW ladar uses a compact external cavity laser that is swept quasi-sinusoidally over 1 THz at a 1 kHz rate. The system simultaneously records the heterodyne FMCW ladar signal and the instantaneous laser frequency at sweep rates up to 3400 THz/s, as measured against a free-running frequency comb (femtosecond fiber laser). Demodulation of the ladar signal against the instantaneous laser frequency yields the range to the target with 1 ms update rates, bandwidth-limited 130 μm resolution and a ~100 nm accuracy that is directly linked to the counted repetition rate of the comb. The precision is <100 nm at the 1 ms update rate and reaches ~6 nm for a 100 ms average. PMID:23938965

  5. A Novel Comb Architecture for Enhancing the Sensitivity of Bulk Mode Gyroscopes

    PubMed Central

    Elsayed, Mohannad Y.; Nabki, Frederic; El-Gamal, Mourad N.

    2013-01-01

    This work introduces a novel architecture for increasing the sensitivity of bulk mode gyroscopes. It is based on adding parallel plate comb drives to the points of maximum vibration amplitude, and tuning the stiffness of the combs. This increases the drive strength and results in a significant sensitivity improvement. The architecture is targeted for technologies with ∼100 nm transducer gaps in order to achieve very high performance devices. In this work, this sensitivity enhancement concept was implemented in SOIMUMPs, a commercial relatively large gap technology. Prototypes were measured to operate at frequencies of ∼1.5 MHz, with quality factors of ∼33,000, at a 10 mTorr vacuum level. Measurements using discrete electronics show a rate sensitivity of 0.31 μV/°/s, corresponding to a capacitance sensitivity of 0.43 aF/°/s/electrode, two orders of magnitude higher than a similar design without combs, fabricated in the same technology.

  6. Recent developments in fiber-based optical frequency comb and its applications

    NASA Astrophysics Data System (ADS)

    Xia, Wei; Chen, Xuzong

    2016-04-01

    Fiber-based optical frequency combs, characterized by compact configuration and outstanding optical properties, have been developed into state-of-the-art precision instruments which are no longer used just for optical frequency metrology, but for a number of applications, including optical clocks, attosecond science, exoplanet searches, medical diagnostics, physicochemical processes control and advanced manufacturing. This short perspective presents some of the milestones and highlights in the evolution of fiber-based optical frequency combs and the technical revolution that are brought by them for a wide range of applications. Along the way, both the challenges and opportunities in the future development of the fiber-based optical frequency comb technology have been described as well.

  7. 75 FR 11559 - Certain Combed Cotton Yarns: Effect of Modification of U.S.-Bahrain FTA Rules of Origin

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-11

    ... COMMISSION Certain Combed Cotton Yarns: Effect of Modification of U.S.- Bahrain FTA Rules of Origin AGENCY...-103-025, Certain Combed Cotton Yarns: Effect of Modification of U.S.-Bahrain FTA Rules Of Origin... effect of the proposed modifications on U.S. trade under the U.S.-Bahrain FTA, total U.S. trade, and...

  8. Is sex selection ethical?

    PubMed

    Fletcher, J C

    1983-01-01

    The argument of this paper is that sex selection, except to avoid sex-linked disorders, is unethical. Two reasons are given: 1) Prima facie examination of any argument for sex selection cannot overcome the unfair and sexist basis of a choice to select the sex of a child. The desire to control the sex of a child is not rational, since any claim that is made for the parents' preference for one sex can be demonstrated to be provided also by the other sex. 2) On an examination of the consequences of sex selection, if it were practiced by parents in significant numbers, the harmful consequences would far outweigh the few fleeting beneficial consequences. The hypothesis that sex selection might reduce population in less developed or overpopulated nations cannot be demonstrated without violation of ethical principles of fairness and beneficence. The paper clarifies and, to an extent, revises a position taken earlier by the author on sex selection by amniocentesis. In an effort to argue that the motives of parents who desire to choose the sex of their child should not be singled out for harsh judgment in societies that allow abortion, the author's position about the ethics of sex selection itself was not directly stated. This paper attempts to strengthen the ethical content of the author's views and recommends a policy for physicians who receive requests from parents to assist them in sex selection. PMID:6579560

  9. Comb/serpentine/cross-bridge test structure for fabrication process evaluation

    NASA Technical Reports Server (NTRS)

    Sayah, Hoshyar R.; Buehler, Martin G.

    1988-01-01

    The comb/serpentine/cross-bridge structure was developed to monitor and evaluate same layer shorts and step coverage problems (open and high-resistance wire over steps) for integrated circuit fabrication processes. The cross-bridge provides local measurements of wire sheet resistance and wirewidth. These local parametric measurements are used in the analysis of the serpentine wire, which identifies step coverage problems. The comb/serpentine/cross-bridge structure was fabricated with 3 microns CMOS/bulk p-well process and tested using a computer-controlled parametric test system.

  10. Electromagnetically induced transparency in rubidium vapor prepared by a comb of short optical pulses

    SciTech Connect

    Sautenkov, Vladimir A.; Rostovtsev, Yuri V.; Ye, C.Y.; Welch, George R.; Kocharovskaya, Olga; Scully, Marlan O.

    2005-06-15

    It was shown by Kocharovskaya and Khanin [Sov. Phys. JETP 63, 945 (1986)] that a comb of optical pulses can induce a ground-state atomic coherence and change the optical response of an atomic medium. In our experiment, we studied the propagation of a comb of optical pulses produced by a mode-locked diode laser in rubidium atomic vapor. Electromagnetically induced transparency (EIT) was observed when the pulse repetition rate is a subharmonic of the hyperfine splitting of the ground state. The width of the EIT resonance is determined by the relaxation rate of the ground-state coherence. Possible applications to magnetometery, atomic clocks, and frequency chains are discussed.

  11. Application of Laser Frequency Combs and Nitrogen Vacancy Diamond Magnetometers to Searches for New Physics

    NASA Astrophysics Data System (ADS)

    Phillips, D. F.; Walsworth, R. L.

    2014-01-01

    Searches for new physics often benefit from improved technologies. Here we discuss possible applications of two emerging technologies to searches for physics beyond the Standard Model. First, laser frequency combs enable broad spectral coverage and coherent conversion between optical and RF signals. We are investigating tests of the nonminimal Standard-Model Extension using frequency combs coupled to broadband optical cavities. Second, nitrogen vacancy centers in diamond enable precision nanoscale magnetometry with applications from imaging to quantum science. We are investigating their use in searches for short-range spin-spin couplings.

  12. Origin and stability of dark pulse Kerr combs in normal dispersion resonators

    NASA Astrophysics Data System (ADS)

    Parra-Rivas, Pedro; Gomila, Damià; Knobloch, Edgar; Coen, Stéphane; Gelens, Lendert

    2016-06-01

    We analyze dark pulse Kerr frequency combs in optical resonators with normal group-velocity dispersion using the Lugiato-Lefever model. We show that in the time domain these correspond to interlocked switching waves between the upper and lower homogeneous states, and explain how this fact accounts for many of their experimentally observed properties. Modulational instability does not play any role in their existence. Furthermore, we provide a detailed map indicating where stable dark pulse Kerr combs can be found in parameter space, and how they are destabilized for increasing values of frequency detuning.

  13. Integrated frequency comb source based Hilbert transformer for wideband microwave photonic phase analysis.

    PubMed

    Nguyen, Thach G; Shoeiby, Mehrdad; Chu, Sai T; Little, Brent E; Morandotti, Roberto; Mitchell, Arnan; Moss, David J

    2015-08-24

    We demonstrate a photonic RF Hilbert transformer for broadband microwave in-phase and quadrature-phase generation based on an integrated frequency optical comb, generated using a nonlinear microring resonator based on a CMOS compatible, high-index contrast, doped-silica glass platform. The high quality and large frequency spacing of the comb enables filters with up to 20 taps, allowing us to demonstrate a quadrature filter with more than a 5-octave (3 dB) bandwidth and an almost uniform phase response. PMID:26368182

  14. Broadly tunable, low timing jitter, high repetition rate optoelectronic comb generator

    PubMed Central

    Metcalf, A. J.; Quinlan, F.; Fortier, T. M.; Diddams, S. A.; Weiner, A. M.

    2016-01-01

    We investigate the low timing jitter properties of a tunable single-pass optoelectronic frequency comb generator. The scheme is flexible in that both the repetition rate and center frequency can be continuously tuned. When operated with 10 GHz comb spacing, the integrated residual pulse-to-pulse timing jitter is 11.35 fs (1 Hz to 10 MHz) with no feedback stabilization. The corresponding phase noise at 1 Hz offset from the photodetected 10 GHz carrier is −100 dBc/Hz. PMID:26865734

  15. Multiheterodyne spectroscopy with optical frequency combs generated from a continuous-wave laser.

    PubMed

    Long, D A; Fleisher, A J; Douglass, K O; Maxwell, S E; Bielska, K; Hodges, J T; Plusquellic, D F

    2014-05-01

    Dual-drive Mach-Zehnder modulators were utilized to produce power-leveled optical frequency combs (OFCs) from a continuous-wave laser. The resulting OFCs contained up to 50 unique frequency components and spanned more than 200 GHz. Simple changes to the modulation frequency allowed for agile control of the comb spacing. These OFCs were then utilized for broadband, multiheterodyne measurements of CO2 using both a multipass cell and an optical cavity. This technique allows for robust measurements of trace gas species and alleviates much of the cost and complexity associated with the use of femtosecond OFCs produced with mode-locked pulsed lasers. PMID:24784078

  16. Coherent frequency combs produced by self frequency modulation in quantum cascade lasers

    SciTech Connect

    Khurgin, J. B.; Dikmelik, Y.; Hugi, A.; Faist, J.

    2014-02-24

    One salient characteristic of Quantum Cascade Laser (QCL) is its very short τ ∼ 1 ps gain recovery time that so far thwarted the attempts to achieve self-mode locking of the device into a train of single pulses. We show theoretically that four wave mixing, combined with the short gain recovery time causes QCL to operate in the self-frequency-modulated regime characterized by a constant power in time domain and stable coherent comb in the frequency domain. Coherent frequency comb may enable many potential applications of QCL's in sensing and measurement.

  17. Frequency-comb-assisted broadband precision spectroscopy with cascaded diode lasers.

    PubMed

    Liu, Junqiu; Brasch, Victor; Pfeiffer, Martin H P; Kordts, Arne; Kamel, Ayman N; Guo, Hairun; Geiselmann, Michael; Kippenberg, Tobias J

    2016-07-01

    Frequency-comb-assisted diode laser spectroscopy, employing both the accuracy of an optical frequency comb and the broad wavelength tuning range of a tunable diode laser, has been widely used in many applications. In this Letter, we present a novel method using cascaded frequency agile diode lasers, which allows us to extend the measurement bandwidth to 37.4 THz (1355-1630 nm) at megahertz resolution with scanning speeds above 1 THz/s. It is demonstrated as a useful tool to characterize a broadband spectrum for molecular spectroscopy, and in particular it enables us to characterize the dispersion of integrated microresonators up to the 4th-order. PMID:27367120

  18. High-bandwidth transfer of phase stability through a fiber frequency comb.

    PubMed

    Scharnhorst, Nils; Wübbena, Jannes B; Hannig, Stephan; Jakobsen, Kornelius; Kramer, Johannes; Leroux, Ian D; Schmidt, Piet O

    2015-07-27

    We demonstrate phase locking of a 729 nm diode laser to a 1542 nm master laser via an erbium-doped-fiber frequency comb, using a transfer-oscillator feedforward scheme which suppresses the effect of comb noise in an unprecedented 1.8 MHz bandwidth. We illustrate its performance by carrying out coherent manipulations of a trapped calcium ion with 99 % fidelity even at few-μs timescales. We thus demonstrate that transfer-oscillator locking can provide sufficient phase stability for high-fidelity quantum logic manipulation even without pre-stabilization of the slave diode laser. PMID:26367634

  19. Two Color FEL Driven by a Comb-like Electron Beam Distribution

    NASA Astrophysics Data System (ADS)

    Chiadroni, E.; Anania, M. P.; Artioli, M.; Bacci, A.; Bellaveglia, M.; Cianchi, A.; Ciocci, F.; Dattoli, G.; Di Giovenale, D.; Di Pirro, G.; Ferrario, M.; Gatti, G.; Giannessi, L.; Mostacci, A.; Musumeci, P.; Palumbo, L.; Petralia, A.; Petrillo, V.; Pompili, R.; Ronsivalle, C.; Rossi, A. R.; Vaccarezza, C.; Villa, F.

    We discuss a new method for the production of trains of FEL radiation pulses based on the FEL emission driven by a comb-like electron beam. In addition, we present recent experimental results on the two color FEL emission as generated at the SPARC_LAB facility: a train of two short (<200 fs) electron bunches, almost overlapped in time, with a comb-like energy distribution, has been injected in the undulator, giving rise to FEL pulses at two characteristic frequencies with multi-peaked time structure. This scheme shows also the versatility of the SPARC photo-injector to generate and manipulate such energy and time distributions.

  20. Time and wavelength interleaved pulse trains generation based on pure phase processing of optical spectral comb

    NASA Astrophysics Data System (ADS)

    Gao, Hongbiao; Chen, Minghua; Chen, Hongwei; Xie, Shizhong

    2014-02-01

    By applying linear phase to optical spectral comb, we experimentally demonstrate that the time interval of the compressed pulse trains with different wavelength can be precisely controlled for the generation of time and wavelength interleaved pulse train. The time and wavelength interleaved pulse train with the repetition rate of 40 GHz and 80 GHz are generated based on this and the possibility to improve the performance of the generated pulse train is also discussed. We also measure the precision of time delay obtained by applying linear phase to the comb.

  1. Micro optical diffusion sensor using a comb-driven micro Fresnel mirror.

    PubMed

    Matoba, Yoshiaki; Taguchi, Yoshihiro; Nagasaka, Yuji

    2015-01-12

    We have developed a novel micro optical diffusion sensor (MODS) with a newly proposed comb-driven-micro Fresnel mirror (CD-MFM) scanner to detect structural changes in biological samples. By controlling the fringe spacing of the excitation laser beam, we can tune the decay time to obtain quick and precise measurements. In this study, the pre-tilted mirror is rotated by vertical comb-driven actuators; the resulting change in the mirror angle alters the fringe spacing. The validity of the proposed mirror scanner is confirmed in simulations and in an experiment using a fabricated prototype device. PMID:25835693

  2. Traceability of laser frequency/wavelength calibration through the frequency comb at Inmetro

    NASA Astrophysics Data System (ADS)

    Silva, I. L. M.; Couceiro, I. B.; Torres, M. A. C.; Costa, P. A.; Grieneisen, H. P. H.

    2016-07-01

    The acquisition of a femtosecond laser comb by the Optical Metrology Division of Inmetro now allows for carrying out high precision calibrations of optical frequencies for lasers which are used as standards of the length unit with gauge block interferometers. The frequency comb is operated as an optical frequency synthesizer and is presently linked to the time unit by a 10 MHz oscillator which is disciplined by GPS. Laser frequencies are determined with accuracy in the range of few parts in 1012. This measurement method now links the length unit, meter, to the SI-second attending the recommendation by the BIPM.

  3. High-resolution terahertz spectroscopy with a single tunable frequency comb.

    PubMed

    Skryl, A S; Pavelyev, D G; Tretyakov, M Y; Bakunov, M I

    2014-12-29

    We report an improvement of three orders of magnitude in the spectral resolution of a recently proposed single-comb terahertz spectroscopy [Opt. Lett.39, 5669 (2014)]. The improvement is achieved by using a femtosecond optical pulse train with a tunable repetition rate. Terahertz comb with tunable spectral line spacing generated by the train is detected via nonlinear mixing with a harmonic of a CW signal from a microwave frequency synthesizer. By applying this technique to the low-pressure gas spectroscopy, we achieved a 100 kHz spectral resolution in measuring separate absorption lines of the rotational manifold of fluoroform (CF3H). PMID:25607192

  4. Optical Frequency Combs From Semiconductor Lasers and Applications in Ultrawideband Signal Processing and Communications

    NASA Astrophysics Data System (ADS)

    Delfyett, Peter J.; Gee, Sangyoun; Choi, Myoung-Taek; Izadpanah, Hossein; Lee, Wangkuen; Ozharar, Sarper; Quinlan, Franklyn; Yilmaz, Tolga

    2006-07-01

    Modelocked semiconductor lasers are used to generate a set of phase-locked optical frequencies on a periodic grid. The periodic and phase coherent nature of the optical frequency combs makes it possible for the realization of high-performance optical and RF arbitrary-waveform synthesis. In addition, the resulting optical frequency components can be used for communication applications relying on direct detection, dense wavelength division multiplexing (WDM), coherent-detection WDM, optical time-division multiplexing, and optical code division multiple access. This paper highlights the recent results in the use of optical frequency combs generated from semiconductors for ultrawideband signal processing and communication applications.

  5. Numerical investigation into the injection-locking phenomena of gain switched lasers for optical frequency comb generation

    SciTech Connect

    Ó Dúill, Sean P. Anandarajah, Prince M.; Zhou, Rui; Barry, Liam P.

    2015-05-25

    We present detailed numerical simulations of the laser dynamics that describe optical frequency comb formation by injection-locking a gain-switched laser. The typical rate equations for semiconductor lasers including stochastic carrier recombination and spontaneous emission suffice to show the injection-locking behavior of gain switched lasers, and we show how the optical frequency comb evolves starting from the free-running state, right through the final injection-locked state. Unlike the locking of continuous wave lasers, we show that the locking range for gain switched lasers is considerably greater because injection locking can be achieved by injecting at frequencies close to one of the comb lines. The quality of the comb lines is formally assessed by calculating the frequency modulation (FM)-noise spectral density and we show that under injection-locking conditions the FM-noise spectral density of the comb lines tend to that of the maser laser.

  6. Real-time dual-comb spectroscopy with a free-running bidirectionally mode-locked fiber laser

    NASA Astrophysics Data System (ADS)

    Mehravar, S.; Norwood, R. A.; Peyghambarian, N.; Kieu, K.

    2016-06-01

    Dual-comb technique has enabled exciting applications in high resolution spectroscopy, precision distance measurements, and 3D imaging. Major advantages over traditional methods can be achieved with dual-comb technique. For example, dual-comb spectroscopy provides orders of magnitude improvement in acquisition speed over standard Fourier-transform spectroscopy while still preserving the high resolution capability. Wider adoption of the technique has, however, been hindered by the need for complex and expensive ultrafast laser systems. Here, we present a simple and robust dual-comb system that employs a free-running bidirectionally mode-locked fiber laser operating at telecommunication wavelength. Two femtosecond frequency combs (with a small difference in repetition rates) are generated from a single laser cavity to ensure mutual coherent properties and common noise cancellation. As the result, we have achieved real-time absorption spectroscopy measurements without the need for complex servo locking with accurate frequency referencing, and relatively high signal-to-noise ratio.

  7. Generation of a 20 GHz train of subpicosecond pulses with a stabilized optical-frequency-comb generator.

    PubMed

    Xiao, Shijun; Hollberg, Leo; Diddams, Scott A

    2009-01-01

    With a modulator-based 10 GHz optical-frequency-comb generator at 1.55 microm, we report a 20 GHz repetitive train of optical pulses as short as 450 fs. The timing stability of the 20 GHz pulses, in addition to the phase for optical-comb modes, shows a strong dependence on the relative frequency detuning between the comb generator's cavity and the seed cw laser. With a new and simple scheme, the comb generator's cavity resonance was locked to a narrow-linewidth seed laser within an estimated optical-frequency range < or = 6 MHz, enabling high-fidelity 20 GHz subpicosecond pulses and stable optical-frequency-comb generation for indefinite periods. PMID:19109648

  8. Ab Initio Theoretical Investigation of the Frequency Comb Structure in the XUV Regime via High Harmonic Generation

    NASA Astrophysics Data System (ADS)

    Carrera, Juan J.; Son, Sang-Kil; Chu, Shih-I.

    2007-06-01

    We present an ab initio quantum investigation of the frequency comb structure formed within each high harmonic generation (HHG) power spectrum driven by a train of equal- spacing short laser pulses. The HHG power spectrum of atomic hydrogen is calculated by solving the time-dependent Schr"o dinger equation accurately and efficiently by means of the time- dependent generalized pseudospectral method. We found that the frequency comb structure is preserved within each harmonic. In addition, the repetition frequency of the comb laser depends upon the pulse separation τ and the spectral width of each individual comb fringe is inversely proportional to the number of pulses (n) used. However, the global HHG power spectrum pattern depends only upon the laser frequency and intensity used and is not sensitive to the τ and n parameters. Finally, the frequency comb structure persists even in the presence of appreciable ionization.

  9. Sex Education: Another View

    ERIC Educational Resources Information Center

    Hamilton, Jennifer

    1977-01-01

    The mother of a 14-year-old mentally retarded boy comments on the viewpoints of Dr. Sol Gordon (a sex education columnist) regarding masturbation, questions on sex, marriage, and the parents' role. (SBH)

  10. Plant Sex Chromosomes.

    PubMed

    Charlesworth, Deborah

    2016-04-29

    Although individuals in most flowering plant species, and in many haploid plants, have both sex functions, dioecious species-in which individuals have either male or female functions only-are scattered across many taxonomic groups, and many species have genetic sex determination. Among these, some have visibly heteromorphic sex chromosomes, and molecular genetic studies are starting to uncover sex-linked markers in others, showing that they too have fully sex-linked regions that are either too small or are located in chromosomes that are too small to be cytologically detectable from lack of pairing, lack of visible crossovers, or accumulation of heterochromatin. Detailed study is revealing that, like animal sex chromosomes, plant sex-linked regions show evidence for accumulation of repetitive sequences and genetic degeneration. Estimating when recombination stopped confirms the view that many plants have young sex-linked regions, making plants of great interest for studying the timescale of these changes. PMID:26653795

  11. Sex-linked recessive

    MedlinePlus

    Inheritance - sex-linked recessive; Genetics - sex-linked recessive; X-linked recessive ... X-linked recessive diseases usually occur in males. Males have only one X chromosome. A single recessive ...

  12. Same sex, no sex, and unaware sex in neurotoxicology.

    PubMed

    Weiss, Bernard

    2011-10-01

    Males and females of virtually all species differ in how they respond to their environment. Because such differences exist in almost all biological realms, including disease patterns and therapeutic outcomes, they have evoked calls by various bodies to incorporate their assessment in research. Neurobehavioral indices pose special questions because, unlike outwardly visible markers, they are described by complex functional outcomes or subtle alterations in brain structure. These divergent responses arise because they are inscribed in the genome itself and then by endocrine mechanisms that govern sexual differentiation of the brain during development and operate throughout life. Other organ systems that exhibit sex differences include the liver, an important consideration for neurotoxicology because it may process many toxic chemicals differentially in males and females. Despite the scope and pervasiveness of sex differences, however, they are disregarded by much of neurotoxicology research. Males predominate in behavioral experiments, few such experiments study both sexes, some investigators fail to even describe the sex of their subjects, and in vitro studies tend to wholly ignore sex, even for model systems aimed at neurological disorders that display marked sex differences. The public is acutely aware of sex differences in behavior, as attested by its appetite for books on the topic. It closely follows debates about the proportion of women in professions that feature science and mathematics. Neurotoxicology, especially in the domain of laboratory research, will be hindered in its ability to translate its findings into human health measures if it assigns sex differences to a minor role. It must also be sensitive to how such debates are framed. Often, the differences evoking the most discussion are subtle in scope. They do not lend themselves to the typical analyses conducted by experimenters; that is, reliance on mean differences and null hypothesis testing. PMID

  13. Reclassification of Bacteriovorax marinus as Halobacteriovorax marinus gen. nov., comb. nov. and Bacteriovorax litoralis as Halobacteriovorax litoralis comb. nov.; description of Halobacteriovoraceae fam. nov. in the class Deltaproteobacteria

    PubMed Central

    Williams, Henry N.; Stine, O. Colin

    2015-01-01

    The taxonomic status of saltwater Bdellovibrio-like prokaryotic predators has been revised to assign species to Halobacteriovorax gen. nov. A reclassification of Bacteriovorax marinus as Halobacteriovorax marinus comb. nov. (type strain ATCC BAA-682T = DSM 15412T) and Bacteriovorax litoralis as Halobacteriovorax litoralis comb. nov. (type strain ATCC BAA-684T = DSM 15409T) is proposed. This revision is necessary because a previous proposal to retain saltwater isolates as species of Bacteriovorax and reclassify Bacteriovorax stolpii as Bacteriolyticum stolpii was not approved. The type species of a genus cannot be reassigned to another genus. Bacteriovorax stolpii is thus retained as the type species of Bacteriovorax and Halobacteriovorax marinus is the type species of Halobacteriovorax and of Halobacteriovoraceae fam. nov. PMID:25406234

  14. Bacterial communities in termite fungus combs are comprised of consistent gut deposits and contributions from the environment.

    PubMed

    Otani, Saria; Hansen, Lars H; Sørensen, Søren J; Poulsen, Michael

    2016-01-01

    Fungus-growing termites (subfamily Macrotermitinae) mix plant forage with asexual spores of their plant-degrading fungal symbiont Termitomyces in their guts and deposit this blend in fungus comb structures, within which the plant matter is degraded. As Termitomyces grows, it produces nodules with asexual spores, which the termites feed on. Since all comb material passes through termite guts, it is inevitable that gut bacteria are also deposited in the comb, but it has remained unknown which bacteria are deposited and whether distinct comb bacterial communities are sustained. Using high-throughput sequencing of the 16S rRNA gene, we explored the bacterial community compositions of 33 fungus comb samples from four termite species (three genera) collected at four South African geographic locations in 2011 and 2013. We identified 33 bacterial phyla, with Firmicutes, Bacteroidetes, Proteobacteria, Actinobacteria, and Candidate division TM7 jointly accounting for 92 % of the reads. Analyses of gut microbiotas from 25 of the 33 colonies showed that dominant fungus comb taxa originate from the termite gut. While gut communities were consistent between 2011 and 2013, comb community compositions shifted over time. These shifts did not appear to be due to changes in the taxa present, but rather due to differences in the relative abundances of primarily gut-derived bacteria within fungus combs. This indicates that fungus comb microbiotas are largely termite species-specific due to major contributions from gut deposits and also that environment affects which gut bacteria dominate comb communities at a given point in time. PMID:26518432

  15. Symbiotic Fungi Produce Laccases Potentially Involved in Phenol Degradation in Fungus Combs of Fungus-Growing Termites in Thailand†

    PubMed Central

    Taprab, Yaovapa; Johjima, Toru; Maeda, Yoshimasa; Moriya, Shigeharu; Trakulnaleamsai, Savitr; Noparatnaraporn, Napavarn; Ohkuma, Moriya; Kudo, Toshiaki

    2005-01-01

    Fungus-growing termites efficiently decompose plant litter through their symbiotic relationship with basidiomycete fungi of the genus Termitomyces. Here, we investigated phenol-oxidizing enzymes in symbiotic fungi and fungus combs (a substrate used to cultivate symbiotic fungi) from termites belonging to the genera Macrotermes, Odontotermes, and Microtermes in Thailand, because these enzymes are potentially involved in the degradation of phenolic compounds during fungus comb aging. Laccase activity was detected in all the fungus combs examined as well as in the culture supernatants of isolated symbiotic fungi. Conversely, no peroxidase activity was detected in any of the fungus combs or the symbiotic fungal cultures. The laccase cDNA fragments were amplified directly from RNA extracted from fungus combs of five termite species and a fungal isolate using degenerate primers targeting conserved copper binding domains of basidiomycete laccases, resulting in a total of 13 putative laccase cDNA sequences being identified. The full-length sequences of the laccase cDNA and the corresponding gene, lcc1-2, were identified from the fungus comb of Macrotermes gilvus and a Termitomyces strain isolated from the same fungus comb, respectively. Partial purification of laccase from the fungus comb showed that the lcc1-2 gene product was a dominant laccase in the fungus comb. These findings indicate that the symbiotic fungus secretes laccase to the fungus comb. In addition to laccase, we report novel genes that showed a significant similarity with fungal laccases, but the gene product lacked laccase activity. Interestingly, these genes were highly expressed in symbiotic fungi of all the termite hosts examined. PMID:16332742

  16. Sex Differences in Cognition

    ERIC Educational Resources Information Center

    Fairweather, Hugh

    1976-01-01

    Sex differences in cognitive skills, grouped into motor, spatial and linguistic areas, are assessed in relation to current theories of cerebral lateralization. Few convincing sex differences exist, either overall, or in interactions with functional localization. Qualifying criteria include age, birth order, culture, sex of experimenter and sex…

  17. Sex Education. Chapter Seventeen.

    ERIC Educational Resources Information Center

    Caster, Jerry A.

    Information and a framework that permits teachers to plan and initiate a successful sex education program for students with mental disabilities is provided. A major aspect of sex education should be its focus on social relationships, emotions, choice-making, and responsibilities to self and others. Sex education should not be viewed as a…

  18. Changing Sex Roles.

    ERIC Educational Resources Information Center

    Worell, Judith

    This article reviews literature on sex role change in children and points to areas which need further research. Competing ideologies which support or reject sex typing of role behaviors are briefly discussed in the introduction. The sources of sex role change are divided into two categories: (1) planned direct intervention programs and (2) natural…

  19. [Scientific sex education].

    PubMed

    1977-01-01

    Sex education should help men and women to realize themselves to the complete fullness of their personality; it should teach respect and comprehension toward life, women, and the family. Sex education can modify those traditional attitudes related to family and society which too often result in irresponsible paternity; sex education should be integrated into the teaching of other scientific disciplines. PMID:12309624

  20. Probing Buffer-Gas Cooled Molecules with Direct Frequency Comb Spectroscopy in the Mid-Infrrared

    NASA Astrophysics Data System (ADS)

    Spaun, Ben; Changala, Bryan; Bjork, Bryce J.; Heckl, Oliver H.; Patterson, David; Doyle, John M.; Ye, Jun

    2015-06-01

    We present the first demonstration of cavity-enhanced direct frequency comb spectroscopy on buffer-gas cooled molecules.By coupling a mid-infrared frequency comb to a high-finesse cavity surrounding a helium buffer-gas chamber, we can gather rotationally resolved absorption spectra with high sensitivity over a broad wavelength region. The measured ˜10 K rotational and translational temperatures of buffer-gas cooled molecules drastically simplify the observed spectra, compared to those of room temperature molecules, and allow for high spectral resolution limited only by Doppler broadening (10-100 MHz). Our system allows for the extension of high-resolution spectroscopy to larger molecules, enabling detailed analysis of molecular structure and dynamics, while taking full advantage of the powerful optical properties of frequency combs. A. Foltynowicz et al. Cavity-enhanced optical frequency comb spectroscopy in the mid-infrared application to trace detection of hydrogen peroxide. Applied Physics B, vol. 110, pp. 163-175, 2013. {D. Patterson and J. M. Doyle. Cooling molecules in a cell for FTMW spectroscopy. Molecular Physics 110, 1757-1766, 2012

  1. Straining graphene with low-temperature compatible electrostatic comb-drive actuators

    NASA Astrophysics Data System (ADS)

    Khodkov, Tymofiy; Goldsche, Matthias; Reichardt, Sven; Stampfer, Christoph

    2015-03-01

    Graphene holds great promises as an active element in future nano electromechanical systems. Therefore, thorough study of electromechanical properties of this 2D material is a crucial step towards its applications in flexible electronics. We present the fabrication and characterization of silicon-based electrostatic comb-drive actuators made for integrating individual graphene sheets. The micromachined comb-drive actuators are designed such that they can induce significant mechanical forces for straining graphene allowing to systematically investigate mechanical and electromechanical properties of high-quality graphene. By using highly doped silicon the comb-drive actuators become compatible with low temperatures, i.e. cryogenic temperatures allowing for quantum electromechanical experiments. Further device functionality is introduced by a local gate that enables the tunability of the chemical potential of the graphene. This approach makes possible a detailed study of the graphene under controlled high strain allowing simultaneous and independent tuning of other external parameters, i.e temperature, charge density, magnetic field. With Raman spectroscopy we measure and characterize mono and bilayer graphene samples at room temperature under applied strains up to 1%. A detailed analysis of data allows clear separation of strain and doping. It is demonstrated that with this technique graphene sheet reproducibly experiences only strain while operating the comb-drive actuator.

  2. Gravity orientation in social wasp comb cells (Vespinae) and the possible role of embedded minerals

    NASA Astrophysics Data System (ADS)

    Ishay, Jacob S.; Barkay, Zahava; Eliaz, Noam; Plotkin, Marian; Volynchik, Stanislav; Bergman, David J.

    2008-04-01

    Social wasps and hornets maintain their nest in the dark. The building of the combs by all Vespinae is always in the direction of the gravitational force of Earth, and in each cell’s ceiling, at least one ‘keystone’ is embedded and fastened by saliva. The sensory mechanisms that enable both building of sizeable symmetrical combs and nursing of the brood in the darkness merit investigation, and the aim of the present study was to identify and characterize the ‘keystones’ that exist in the ceiling and in the walls of the social wasp comb cells. Bio-ferrography was used to isolate magnetic particles on slides. These slides, as well as original cells, were analyzed in an environmental scanning electron microscope by a variety of analytical tools. It was found that both the roof and the walls of each comb cell bear minerals, like ferrites, as well as Ti and Zr. The latter two elements are less abundant in the soil around the nest. Ti and Zr are known to reflect infrared (IR) light. IR imaging showed a thermoregulatory center in the dorsal thorax of the adult Oriental hornet. It is not known yet whether these insects can sense IR light.

  3. Progress with a green astro-comb for exoplanet searches. Type: poster

    NASA Astrophysics Data System (ADS)

    Phillips, David F.; Li, Chih-Hao; Glenday, Alexander; Sasselov, Dimitar; Szentgyorgyi, Andrew; Walsworth, Ronald L.

    2016-05-01

    Searches for extrasolar planets using the precision stellar radial velocity (RV) measurement technique are approaching Earth-like planet sensitivity. Astro-combs, which consist of a laser frequency comb, coherent wavelength shifting mechanism (such as a doubling crystal and photonic crystal fiber), and a mode-filtering Fabry-Perot cavity (FPC), provide a promising route to increased accuracy and long-term stability on the astrophysical spectrograph calibration. We first present the design of a green astro-comb from an octave spanning Ti:Sapphire laser, spectrally broadened by custom tapered PCF to the visible band via fiber-optic Cherenkov radiation for frequency shifting, and filtered by a broadband FPC, constructed by a pair of complementary chirped mirrors. We also present results from three years of operation of the astro-comb calibrating the HARPS-N spectrograph at the Italian National Telescope on La Palma, Canary Islands, including its use in measurements of solar radial velocities as well as its use in searches for extrasolar planets.

  4. Power, Prayers, and Protection: Comb Ridge as a Case Study in Navajo Thought

    ERIC Educational Resources Information Center

    McPherson, Robert S.

    2010-01-01

    Beginning in 2005, a five-year survey of cultural resources began to unfold in southeastern Utah along a prominent sandstone rock formation known as Comb Ridge. This visually dramatic monocline stretches a considerable distance from the southwestern corner of Blue Mountain (Abajos) in Utah to Kayenta, Arizona, approximately one hundred miles to…

  5. Fibers and combs: weaving a portable frequency reference in the near-IR

    NASA Astrophysics Data System (ADS)

    Corwin, Kristan

    2009-05-01

    Ten years after the advent of femtosecond optical frequency combs, they are now used for many applications. Here, we use near infrared combs to characterize and develop portable frequency references based on gas-filled hollow optical fibers. We explore the accuracy and stability of saturated absorption features in acetylene gas confined inside both 10 micron core diameter photonic bandgap fibers and ˜60 micron core diameter kagome-structured photonic crystal fibers. A cw fiber laser referenced to these features has resulted in stabilities of ˜10-11 in 1 s, competitive with iodine-stabilized HeNe lasers. Most of these studies have been performed using a femtosecond fiber laser that relies on a carbon nanotube saturable absorber. However, we have also explored Cr:forsterite femtosecond lasers with intracavity prisms, which reveal dramatic narrowing of the carrier-envelope offset beat when a knife edge is inserted in the cavity. Such observations and subsequent noise dynamics studies will lead to a better understanding of noise in these solid state combs, making Cr:forsterite laser combs more competitive for spectroscopy and other applications.

  6. Look closer: Time sequence photography of Roosters Comb in the Sheep Creek Range, Nevada

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The importance of understanding natural landscape changes is key in properly determining rangeland ecology. Time sequence photography allows a snapshot of a landscape to be documented and enables the ability to compare natural changes overtime. Photographs of Roosters Comb were taken from the same v...

  7. Phrenology, Education, and the Politics of Human Nature: The Thought and Influence of George Combe.

    ERIC Educational Resources Information Center

    Tomlinson, Stephen

    1997-01-01

    Reviews the career and contributions of George Combe, an Edinburgh lawyer who proselytized for the cause of using phrenology in education. Although dismissed today as pseudoscience, phrenology (attributing various character traits to specific locations in the brain) was taken seriously as a science during the early 19th century. (MJP)

  8. Hexagonal comb cells of honeybees are not produced via a liquid equilibrium process

    NASA Astrophysics Data System (ADS)

    Bauer, Daniel; Bienefeld, Kaspar

    2013-01-01

    The nests of European honeybees ( Apis mellifera) are organised into wax combs that contain many cells with a hexagonal structure. Many previous studies on comb-building behaviour have been made in order to understand how bees produce this geometrical structure; however, it still remains a mystery. Direct construction of hexagons by bees was suggested previously, while a recent hypothesis postulated the self-organised construction of hexagonal comb cell arrays; however, infrared and thermographic video observations of comb building in the present study failed to support the self-organisation hypothesis because bees were shown to be engaged in direct construction. Bees used their antennae, mandibles and legs in a regular sequence to manipulate the wax, while some bees supported their work by actively warming the wax. During the construction of hexagonal cells, the wax temperature was between 33.6 and 37.6 °C. This is well below 40 °C, i.e. the temperature at which wax is assumed to exist in the liquid equilibrium that is essential for self-organised building.

  9. Hexagonal comb cells of honeybees are not produced via a liquid equilibrium process.

    PubMed

    Bauer, Daniel; Bienefeld, Kaspar

    2013-01-01

    The nests of European honeybees (Apis mellifera) are organised into wax combs that contain many cells with a hexagonal structure. Many previous studies on comb-building behaviour have been made in order to understand how bees produce this geometrical structure; however, it still remains a mystery. Direct construction of hexagons by bees was suggested previously, while a recent hypothesis postulated the self-organised construction of hexagonal comb cell arrays; however, infrared and thermographic video observations of comb building in the present study failed to support the self-organisation hypothesis because bees were shown to be engaged in direct construction. Bees used their antennae, mandibles and legs in a regular sequence to manipulate the wax, while some bees supported their work by actively warming the wax. During the construction of hexagonal cells, the wax temperature was between 33.6 and 37.6 °C. This is well below 40 °C, i.e. the temperature at which wax is assumed to exist in the liquid equilibrium that is essential for self-organised building. PMID:23149932

  10. Coherent optical frequency-combs-based wideband signal channelization and analog to digital conversion

    NASA Astrophysics Data System (ADS)

    Yin, Feifei; Dai, Yitang; Li, Jianqiang; Xu, Kun

    2014-11-01

    We demonstrate a photonic-assisted broadband radio frequency (RF) channelization scheme based on dual coherent optical frequency combs (OFCs). The advantages include coarse optical alignment requirement, ideal rectangular frequency response in each channel without any ultra-narrow optical filters, and digitalized output for further processing. Meanwhile, the channel frequency response and crosstalk of the scheme are also evaluated experimentally.

  11. Adaptive sampling dual terahertz comb spectroscopy using dual free-running femtosecond lasers

    PubMed Central

    Yasui, Takeshi; Ichikawa, Ryuji; Hsieh, Yi-Da; Hayashi, Kenta; Cahyadi, Harsono; Hindle, Francis; Sakaguchi, Yoshiyuki; Iwata, Tetsuo; Mizutani, Yasuhiro; Yamamoto, Hirotsugu; Minoshima, Kaoru; Inaba, Hajime

    2015-01-01

    Terahertz (THz) dual comb spectroscopy (DCS) is a promising method for high-accuracy, high-resolution, broadband THz spectroscopy because the mode-resolved THz comb spectrum includes both broadband THz radiation and narrow-line CW-THz radiation characteristics. In addition, all frequency modes of a THz comb can be phase-locked to a microwave frequency standard, providing excellent traceability. However, the need for stabilization of dual femtosecond lasers has often hindered its wide use. To overcome this limitation, here we have demonstrated adaptive-sampling THz-DCS, allowing the use of free-running femtosecond lasers. To correct the fluctuation of the time and frequency scales caused by the laser timing jitter, an adaptive sampling clock is generated by dual THz-comb-referenced spectrum analysers and is used for a timing clock signal in a data acquisition board. The results not only indicated the successful implementation of THz-DCS with free-running lasers but also showed that this configuration outperforms standard THz-DCS with stabilized lasers due to the slight jitter remained in the stabilized lasers. PMID:26035687

  12. Quantum theory of phase correlations in optical frequency combs generated by stimulated Raman scattering

    SciTech Connect

    Wu Chunbai; Raymer, M. G.; Wang, Y. Y.; Benabid, F.

    2010-11-15

    We explore theoretically the phase correlation between multiple generated sidebands in a Raman optical frequency comb under conditions of spontaneous initiation from quantum zero-point noise. We show that there is a near-deterministic correlation between sideband phases in each laser shot which may lead to synthesis of attosecond pulse trains.

  13. Effect of partial comb and wattle trim on pullet behavior and thermoregulation

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The wattles and comb of chickens are important for thermoregulation allowing for heat exchange during high temperatures. These integumentary tissues are sometimes trimmed to prevent tears if caught on cage equipment and to also improve feed efficiency; however, the procedure itself could be painful ...

  14. Molecular fingerprinting with the resolved modes of a femtosecond laser frequency comb.

    PubMed

    Diddams, Scott A; Hollberg, Leo; Mbele, Vela

    2007-02-01

    The control of the broadband frequency comb emitted from a mode-locked femtosecond laser has permitted a wide range of scientific and technological advances--ranging from the counting of optical cycles for next-generation atomic clocks to measurements of phase-sensitive high-field processes. A unique advantage of the stabilized frequency comb is that it provides, in a single laser beam, about a million optical modes with very narrow linewidths and absolute frequency positions known to better than one part in 10(15) (ref. 5). One important application of this vast array of highly coherent optical fields is precision spectroscopy, in which a large number of modes can be used to map internal atomic energy structure and dynamics. However, an efficient means of simultaneously identifying, addressing and measuring the amplitude or relative phase of individual modes has not existed. Here we use a high-resolution disperser to separate the individual modes of a stabilized frequency comb into a two-dimensional array in the image plane of the spectrometer. We illustrate the power of this technique for high-resolution spectral fingerprinting of molecular iodine vapour, acquiring in a few milliseconds absorption images covering over 6 THz of bandwidth with high frequency resolution. Our technique for direct and parallel accessing of stabilized frequency comb modes could find application in high-bandwidth spread-spectrum communications with increased security, high-resolution coherent quantum control, and arbitrary optical waveform synthesis with control at the optical radian level. PMID:17287805

  15. Toward a low-jitter 10 GHz pulsed source with an optical frequency comb generator.

    PubMed

    Xiao, Shijun; Hollberg, Leo; Newbury, Nathan R; Diddams, Scott A

    2008-06-01

    We demonstrate low residual timing jitter of 10 GHz pulses from a 1.55 ?m optical frequency comb generator based on a doubly-resonant electro-optic modulator. The comb spectral phase is shown to be linear but of different slopes for the two sides of the optical spectrum. The linear phase delay predicts well the measured timing delay of the two pulse trains from the comb generator. The pulse timing jitter is analyzed, and we illustrate that the pump laser's linewidth plays a dominant role in the timing jitter. For Fourier frequencies from 1 Hz to 10 MHz, integrated residual timing jitter at 10 GHz was reduced from approximately 94 fs to approximately 8 fs when the pump laser's linewidth was reduced from approximately 10 MHz to approximately 1 kHz. An electronic servo was then used to stabilize the Fabry-Pérot cavity in the comb generator. Integrated residual timing jitter was further reduced to approximately 6 fs, and the corresponding residual phase noise power density is -105 dBc/Hz at 1 Hz frequency offset from the 10 GHz pulse carrier. PMID:18545564

  16. Osho - Insights on sex.

    PubMed

    Nagaraj, Anil Kumar Mysore

    2013-01-01

    Sex is a mysterious phenomenon, which has puzzled even great sages. Human beings have researched and mastered the biology of sex. But that is not all. Sex needs to be understood from the spiritual perspective too. The vision of Osho is an enlightening experience in this regard. Out of the thousands of lectures, five lectures on sex made Osho most notorious. Born into a Jain family of Madhya Pradesh, Rajneesh, who later wanted himself to be called Osho, is a great master. He has spoken volumes on a wide range of topics ranging from sex to super-consciousness. His contributions in the area of sex are based on the principles of "Tantra" which has its origin from Buddhism. This article focuses on his life and insights on sex, which if understood properly, can be a stepping stone for enlightenment. PMID:23858266

  17. Osho - Insights on sex

    PubMed Central

    Nagaraj, Anil Kumar Mysore

    2013-01-01

    Sex is a mysterious phenomenon, which has puzzled even great sages. Human beings have researched and mastered the biology of sex. But that is not all. Sex needs to be understood from the spiritual perspective too. The vision of Osho is an enlightening experience in this regard. Out of the thousands of lectures, five lectures on sex made Osho most notorious. Born into a Jain family of Madhya Pradesh, Rajneesh, who later wanted himself to be called Osho, is a great master. He has spoken volumes on a wide range of topics ranging from sex to super-consciousness. His contributions in the area of sex are based on the principles of “Tantra” which has its origin from Buddhism. This article focuses on his life and insights on sex, which if understood properly, can be a stepping stone for enlightenment. PMID:23858266

  18. XUV frequency-comb metrology on the ground state of helium

    SciTech Connect

    Kandula, Dominik Z.; Gohle, Christoph; Pinkert, Tjeerd J.; Ubachs, Wim; Eikema, Kjeld S. E.

    2011-12-15

    The operation of a frequency comb at extreme ultraviolet (xuv) wavelengths based on pairwise amplification and nonlinear upconversion to the 15th harmonic of pulses from a frequency-comb laser in the near-infrared range is reported. It is experimentally demonstrated that the resulting spectrum at 51 nm is fully phase coherent and can be applied to precision metrology. The pulses are used in a scheme of direct-frequency-comb excitation of helium atoms from the ground state to the 1s4p and 1s5p {sup 1} P{sub 1} states. Laser ionization by auxiliary 1064 nm pulses is used to detect the excited-state population, resulting in a cosine-like signal as a function of the repetition rate of the frequency comb with a modulation contrast of up to 55%. Analysis of the visibility of this comb structure, thereby using the helium atom as a precision phase ruler, yields an estimated timing jitter between the two upconverted-comb laser pulses of 50 attoseconds, which is equivalent to a phase jitter of 0.38 (6) cycles in the xuv at 51 nm. This sets a quantitative figure of merit for the operation of the xuv comb and indicates that extension to even shorter wavelengths should be feasible. The helium metrology investigation results in transition frequencies of 5 740 806 993 (10) and 5 814 248 672 (6) MHz for excitation of the 1s4p and 1s5p {sup 1} P{sub 1} states, respectively. This constitutes an important frequency measurement in the xuv, attaining high accuracy in this windowless part of the electromagnetic spectrum. From the measured transition frequencies an eight-fold-improved {sup 4}He ionization energy of 5 945 204 212 (6) MHz is derived. Also, a new value for the {sup 4}He ground-state Lamb shift is found of 41 247 (6) MHz. This experimental value is in agreement with recent theoretical calculations up to order m{alpha}{sup 6} and m{sup 2}/M{alpha}{sup 5}, but with a six-times-higher precision, therewith providing a stringent test of quantum electrodynamics in bound two

  19. Astronomical optical frequency comb generation in nonlinear fibres and ring resonators: optimization studies

    NASA Astrophysics Data System (ADS)

    Chavez Boggio, J. M.; Fremberg, T.; Bodenmüller, D.; Wysmolek, M.; Sanyic, H.; Fernando, H.; Neumann, J.; Kracht, D.; Haynes, R.; Roth, M. M.

    2012-09-01

    We here discuss recent progress on astronomical optical frequency comb generation at innoFSPEC-Potsdam. Two different platforms (and approaches) are numerically and experimentally investigated targeting medium and low resolution spectrographs at astronomical facilities in which innoFSPEC is currently involved. In the first approach, a frequency comb is generated by propagating two lasers through three nonlinear stages - the first two stages serve for the generation of low-noise ultra-short pulses, while the final stage is a low-dispersion highly-nonlinear fibre where the pulses undergo strong spectral broadening. In our approach, the wavelength of one of the lasers can be tuned allowing the comb line spacing being continuously varied during the calibration procedure - this tuning capability is expected to improve the calibration accuracy since the CCD detector response can be fully scanned. The input power, the dispersion, the nonlinear coefficient, and fibre lengths in the nonlinear stages are defined and optimized by solving the Generalized Nonlinear Schrodinger Equation. Experimentally, we generate the 250GHz line-spacing frequency comb using two narrow linewidth lasers that are adiabatically compressed in a standard fibre first and then in a double-clad Er/Yb doped fibre. The spectral broadening finally takes place in a highly nonlinear fibre resulting in an astro-comb with 250 calibration lines (covering a bandwidth of 500 nm) with good spectral equalization. In the second approach, we aim to generate optical frequency combs in dispersion-optimized silicon nitride ring resonators. A technique for lowering and flattening the chromatic dispersion in silicon nitride waveguides with silica cladding is proposed and demonstrated. By minimizing the waveguide dispersion in the resonator two goals are targeted: enhancing the phase matching for non-linear interactions and producing equally spaced resonances. For this purpose, instead of one cladding layer our design

  20. A 12.5 GHz-spaced optical frequency comb spanning >400 nm for near-infrared astronomical spectrograph calibration

    NASA Astrophysics Data System (ADS)

    Quinlan, F.; Ycas, G.; Osterman, S.; Diddams, S. A.

    2010-06-01

    A 12.5 GHz-spaced optical frequency comb locked to a global positioning system disciplined oscillator for near-infrared (IR) spectrograph calibration is presented. The comb is generated via filtering a 250 MHz-spaced comb. Subsequent nonlinear broadening of the 12.5 GHz comb extends the wavelength range to cover 1380-1820 nm, providing complete coverage over the H-band transmission window of earth's atmosphere. Finite suppression of spurious sidemodes, optical linewidth, and instability of the comb has been examined to estimate potential wavelength biases in spectrograph calibration. Sidemode suppression varies between 20 and 45 dB, and the optical linewidth is ~350 kHz at 1550 nm. The comb frequency uncertainty is bounded by +/-30 kHz (corresponding to a radial velocity of +/-5 cm/s), limited by the global positioning system disciplined oscillator reference. These results indicate that this comb can readily support radial velocity measurements below 1 m/s in the near IR.

  1. Scalable and reconfigurable generation of flat optical comb for WDM-based next-generation broadband optical access networks

    NASA Astrophysics Data System (ADS)

    Chen, Chen; Zhang, Chongfu; Zhang, Wei; Jin, Wei; Qiu, Kun

    2014-06-01

    A tunable comb generator (TCG) by cascading a single phase modulator (PM) with two identical intensity modulators (IMs) is proposed for the scalable and reconfigurable generation of flat optical comb. Detailed theoretical analysis is performed to find out the optimized condition for flat optical comb generation using the proposed TCG and the scalability of the generated optical comb is also analyzed under the optimized condition. An experiment is conducted to verify the feasibility of the TCG and the experimental results agree well with the theoretical prediction. The reconfigurability and stability of the obtained optical comb are discussed as well in the experiment. After that, the obtained optical comb is utilized as the optical source for a wavelength-division multiplexed radio-over-fiber (WDM-RoF) system and a hybrid WDM orthogonal frequency-division multiple access passive optical network (WDM-OFDMA-PON). Two corresponding experimental demonstrations are presented to verify the feasibility of employing the obtained flat optical comb as the WDM optical source, respectively. In the WDM-RoF system, 17 WDM channels each carrying 16×5 Gb/s non-return-to-zero (NRZ) data have been up-converted to 10 GHz simultaneously. In the hybrid WDM-OFDMA-PON, 17-channel OFDM-WDM double-sideband (DSB) signal achieving 10.85 Gb/s traffic per channel is successfully transmitted for both wired baseband OFDM access and wireless 10 GHz OFDM access.

  2. A 12.5 GHz-spaced optical frequency comb spanning >400 nm for near-infrared astronomical spectrograph calibration

    SciTech Connect

    Quinlan, F.; Diddams, S. A.; Ycas, G.; Osterman, S.

    2010-06-15

    A 12.5 GHz-spaced optical frequency comb locked to a global positioning system disciplined oscillator for near-infrared (IR) spectrograph calibration is presented. The comb is generated via filtering a 250 MHz-spaced comb. Subsequent nonlinear broadening of the 12.5 GHz comb extends the wavelength range to cover 1380-1820 nm, providing complete coverage over the H-band transmission window of earth's atmosphere. Finite suppression of spurious sidemodes, optical linewidth, and instability of the comb has been examined to estimate potential wavelength biases in spectrograph calibration. Sidemode suppression varies between 20 and 45 dB, and the optical linewidth is {approx}350 kHz at 1550 nm. The comb frequency uncertainty is bounded by {+-}30 kHz (corresponding to a radial velocity of {+-}5 cm/s), limited by the global positioning system disciplined oscillator reference. These results indicate that this comb can readily support radial velocity measurements below 1 m/s in the near IR.

  3. A 12.5 GHz-spaced optical frequency comb spanning >400 nm for near-infrared astronomical spectrograph calibration.

    PubMed

    Quinlan, F; Ycas, G; Osterman, S; Diddams, S A

    2010-06-01

    A 12.5 GHz-spaced optical frequency comb locked to a global positioning system disciplined oscillator for near-infrared (IR) spectrograph calibration is presented. The comb is generated via filtering a 250 MHz-spaced comb. Subsequent nonlinear broadening of the 12.5 GHz comb extends the wavelength range to cover 1380-1820 nm, providing complete coverage over the H-band transmission window of earth's atmosphere. Finite suppression of spurious sidemodes, optical linewidth, and instability of the comb has been examined to estimate potential wavelength biases in spectrograph calibration. Sidemode suppression varies between 20 and 45 dB, and the optical linewidth is approximately 350 kHz at 1550 nm. The comb frequency uncertainty is bounded by +/-30 kHz (corresponding to a radial velocity of +/-5 cm/s), limited by the global positioning system disciplined oscillator reference. These results indicate that this comb can readily support radial velocity measurements below 1 m/s in the near IR. PMID:20590223

  4. Generation of green frequency comb from chirped χ{sup (2)} nonlinear photonic crystals

    SciTech Connect

    Lai, C.-M.; Chang, K.-H.; Yang, Z.-Y.; Fu, S.-H.; Tsai, S.-T.; Hsu, C.-W.; Peng, L.-H.; Yu, N. E.; Boudrioua, A.; Kung, A. H.

    2014-12-01

    Spectrally broad frequency comb generation over 510–555 nm range was reported on chirped quasi-phase-matching (QPM) χ{sup (2)} nonlinear photonic crystals of 12 mm length with periodicity stepwise increased from 5.9 μm to 7.1 μm. When pumped with nanosecond infrared (IR) frequency comb derived from a QPM optical parametric oscillator (OPO) and spanned over 1040 nm to 1090 nm wavelength range, the 520 nm to 545 nm up-converted green spectra were shown to consist of contributions from (a) second-harmonic generation among the signal or the idler modes, and (b) sum-frequency generation (SFG) from the neighboring pairs of the signal or the idler modes. These mechanisms led the up-converted green frequency comb to have the same mode spacing of 450 GHz as that in the IR-OPO pump comb. As the pump was further detuned from the aforementioned near-degeneracy point and moved toward the signal (1020–1040 nm) and the idler (1090–1110 nm) spectral range, the above QPM parametric processes were preserved in the chirped QPM devices to support up-converted green generation in the 510–520 nm and the 545–555 nm spectral regime. Additional 530–535 nm green spectral generation was also observed due to concurrence of multi-wavelength SFG processes between the (signal, idler) mode pairs. These mechanisms facilitate the chirped QPM device to support a single-pass up-conversion efficiency ∼10% when subject to an IR-OPO pump comb with 200 mW average power operated near- or off- the degeneracy point.

  5. Generation of green frequency comb from chirped χ(2) nonlinear photonic crystals

    NASA Astrophysics Data System (ADS)

    Lai, C.-M.; Chang, K.-H.; Yang, Z.-Y.; Fu, S.-H.; Tsai, S.-T.; Hsu, C.-W.; Yu, N. E.; Boudrioua, A.; Kung, A. H.; Peng, L.-H.

    2014-12-01

    Spectrally broad frequency comb generation over 510-555 nm range was reported on chirped quasi-phase-matching (QPM) χ(2) nonlinear photonic crystals of 12 mm length with periodicity stepwise increased from 5.9 μm to 7.1 μm. When pumped with nanosecond infrared (IR) frequency comb derived from a QPM optical parametric oscillator (OPO) and spanned over 1040 nm to 1090 nm wavelength range, the 520 nm to 545 nm up-converted green spectra were shown to consist of contributions from (a) second-harmonic generation among the signal or the idler modes, and (b) sum-frequency generation (SFG) from the neighboring pairs of the signal or the idler modes. These mechanisms led the up-converted green frequency comb to have the same mode spacing of 450 GHz as that in the IR-OPO pump comb. As the pump was further detuned from the aforementioned near-degeneracy point and moved toward the signal (1020-1040 nm) and the idler (1090-1110 nm) spectral range, the above QPM parametric processes were preserved in the chirped QPM devices to support up-converted green generation in the 510-520 nm and the 545-555 nm spectral regime. Additional 530-535 nm green spectral generation was also observed due to concurrence of multi-wavelength SFG processes between the (signal, idler) mode pairs. These mechanisms facilitate the chirped QPM device to support a single-pass up-conversion efficiency ˜10% when subject to an IR-OPO pump comb with 200 mW average power operated near- or off- the degeneracy point.

  6. All solid state mid-infrared dual-comb spectroscopy platform based on QCL technology

    NASA Astrophysics Data System (ADS)

    Hugi, Andreas; Geiser, Markus; Villares, Gustavo; Cappelli, Francesco; Blaser, Stephane; Faist, Jérôme

    2015-01-01

    We develop a spectroscopy platform for industrial applications based on semiconductor quantum cascade laser (QCL) frequency combs. The platform's key features will be an unmatched combination of bandwidth of 100 cm-1, resolution of 100 kHz, speed of ten to hundreds of μs as well as size and robustness, opening doors to beforehand unreachable markets. The sensor can be built extremely compact and robust since the laser source is an all-electrically pumped semiconductor optical frequency comb and no mechanical elements are required. However, the parallel acquisition of dual-comb spectrometers comes at the price of enormous data-rates. For system scalability, robustness and optical simplicity we use free-running QCL combs. Therefore no complicated optical locking mechanisms are required. To reach high signal-to-noise ratios, we develop an algorithm, which is based on combination of coherent and non-coherent averaging. This algorithm is specifically optimized for free-running and small footprint, therefore high-repetition rate, comb sources. As a consequence, our system generates data-rates of up to 3.2 GB/sec. These data-rates need to be reduced by several orders of magnitude in real-time in order to be useful for spectral fitting algorithms. We present the development of a data-treatment solution, which reaches a single-channel throughput of 22% using a standard laptop-computer. Using a state-of-the art desktop computer, the throughput is increased to 43%. This is combined with a data-acquisition board to a stand-alone data processing unit, allowing real-time industrial process observation and continuous averaging to achieve highest signal fidelity.

  7. Threshold conditions, energy spectrum and bands generated by locally periodic Dirac comb potentials

    NASA Astrophysics Data System (ADS)

    Dharani, M.; Shastry, C. S.

    2016-01-01

    We derive expressions for polynomials governing the threshold conditions for different types of locally periodic Dirac comb potentials comprising of attractive and combination of attractive and repulsive delta potential terms confined symmetrically inside a one dimensional box of fixed length. The roots of these polynomials specify the conditions on the potential parameters in order to generate threshold energy bound states. The mathematical and numerical methods used by us were first formulated in our earlier works and it is also very briefly summarized in this paper. We report a number of mathematical results pertaining to the threshold conditions and these are useful in controlling the number of negative energy states as desired. We further demonstrate the correlation between the distribution of roots of these polynomials and negative energy eigenvalues. Using these results as basis, we investigate the energy bands in the positive energy spectrum for the above specified Dirac comb potentials and also for the corresponding repulsive case. In the case of attractive Dirac comb the base energy of the each band excluding the first band coincides with specific eigenvalue of the confining box whereas in the repulsive case it coincides with the band top. We deduce systematic correlation between band gaps, band spreads and box eigenvalues and explain the physical reason for the vanishing of band pattern at higher energies. In the case of Dirac comb comprising of orderly arranged attractive and repulsive delta potentials, specific box eigenvalues occur in the middle of each band excluding the first band. From our study we find that by controlling the number and strength parameters of delta terms in the Dirac comb and the size of confining box it is possible to generate desired types of band formations. We believe the results from our systematic analysis are useful and relevant in the study of various one dimensional systems of physical interest in areas like nanoscience.

  8. Generation of a frequency comb spanning more than 3.6 octaves from ultraviolet to mid infrared.

    PubMed

    Iwakuni, Kana; Okubo, Sho; Tadanaga, Osamu; Inaba, Hajime; Onae, Atsushi; Hong, Feng-Lei; Sasada, Hiroyuki

    2016-09-01

    We have observed an ultra-broadband frequency comb with a wavelength range of at least 0.35 to 4.4 μm in a ridge-waveguide-type periodically poled lithium niobate device. The PPLN waveguide is pumped by a 1.0-2.4 μm wide frequency comb with an average power of 120 mW generated using an erbium-based mode-locked fiber laser and a following highly nonlinear fiber. The coherence of the extended comb is confirmed in both the visible (around 633 nm) and the mid-infrared regions. PMID:27607952

  9. Selection and amplification of modes of an optical frequency comb using a femtosecond laser injection-locking technique

    SciTech Connect

    Moon, H. S.; Kim, E. B.; Park, S. E.; Park, C. Y.

    2006-10-30

    The authors have demonstrated the selection and the amplification of the components of an optical frequency comb using a femtosecond laser injectionlocking technique. The author used a mode-locked femtosecond Ti:sapphire laser as the master laser and a single-mode diode laser as the slave laser. The femtosecond laser injection-locking technique was applied to a filter for mode selection of the optical frequency comb and an amplifier for amplification of the selected mode. The authors could obtain the laser source selected only the desired mode of the optical frequency comb and amplified the power of the selected modes several thousand times.

  10. Simultaneous low noise radio frequency tone and narrow linewidth optical comb generation from a regeneratively mode-locked laser

    NASA Astrophysics Data System (ADS)

    Ozdur, Ibrahim; Ozharar, Sarper; Delfyett, Peter J.

    2014-10-01

    A regeneratively mode-locked laser with simultaneous low noise radio frequency (RF) tone and optical comb generation is presented. The laser does not need any external RF signal and emits a pulse train at ˜10 GHz repetition rate with a 1.5-ps optical pulse width after compression. The generated RF tone has a signal-to-noise ratio of 121 dB/Hz and an RF fluctuation of 10-9 over 0.1 s. The optical frequency comb spacing is also at ˜10 GHz and the optical comb tooth has a linewidth of <1 kHz.

  11. Wide-bandwidth phase lock between a CW laser and a frequency comb based on a feed-forward configuration.

    PubMed

    Sala, T; Gatti, D; Gambetta, A; Coluccelli, N; Galzerano, G; Laporta, P; Marangoni, M

    2012-07-01

    Wide-bandwidth phase lock between the tooth of a frequency comb and a CW extended-cavity diode laser at 1.55 μm is achieved by the use of an acousto-optical frequency shifter in a feed-forward configuration. The coherence properties of the comb are efficiently transferred to the CW laser, whose linewidth is narrowed down to the ∼10 KHz comb level. A maximum control bandwidth of ∼0.6 MHz has been experimentally achieved, limited by the transit time of the acoustic wave inside the frequency shifter. PMID:22743465

  12. Plant sex chromosome evolution.

    PubMed

    Charlesworth, Deborah

    2013-01-01

    It is now well established that plants have an important place in studies of sex chromosome evolution because of the repeated independent evolution of separate sexes and sex chromosomes. There has been considerable recent progress in studying plant sex chromosomes. In this review, I focus on how these recent studies have helped clarify or answer several important questions about sex chromosome evolution, and I shall also try to clarify some common misconceptions. I also outline future work that will be needed to make further progress, including testing some important ideas by genetic, molecular, and developmental approaches. Systems with different ages can clearly help show the time course of events during changes from an ancestral co-sexual state (hermaphroditism or monoecy), and I will also explain how different questions can be studied in lineages whose dioecy or sex chromosomes evolved at different times in the past. PMID:23125359

  13. Sex Differences in Lifespan.

    PubMed

    Austad, Steven N; Fischer, Kathleen E

    2016-06-14

    Sex differences in longevity can provide insights into novel mechanisms of aging, yet they have been little studied. Surprisingly, sex-specific longevity patterns are best known in wild animals. Evolutionary hypotheses accounting for longevity patterns in natural populations include differential vulnerability to environmental hazards, differential intensity of sexual selection, and distinct patterns of parental care. Mechanistic hypotheses focus on hormones, asymmetric inheritance of sex chromosomes and mitochondria. Virtually all intensively studied species show conditional sex differences in longevity. Humans are the only species in which one sex is known to have a ubiquitous survival advantage. Paradoxically, although women live longer, they suffer greater morbidity particularly late in life. This mortality-morbidity paradox may be a consequence of greater connective tissue responsiveness to sex hormones in women. Human females' longevity advantage may result from hormonal influences on inflammatory and immunological responses, or greater resistance to oxidative damage; current support for these mechanisms is weak. PMID:27304504

  14. Chipscale optical frequency combs: from soliton physics to coherent communication (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Brasch, Victor; Geiselmann, Michael; Herr, Tobias; Lihachev, Grigoriy; Pfeiffer, Martin H. P.; Gorodetsky, Michael L.; Kippenberg, Tobias J.

    2016-04-01

    In our experiment we use silicon nitride waveguides embedded in silicon dioxide on a silicon chip. The cross section of the waveguide is approximately 1.8µm width by 0.8µm height and the ring resonator has a radius of 120µm. This resonator is coupled to a bus waveguide that is used to couple the continuous wave pump light into the resonator and the light from the resonator out again. The pump laser is an amplified diode laser which provides around 2W of pump power in the bus waveguide on the photonic chip. If the pump light is in resonance with one of the resonances of the resonator we can generate a frequency comb from the pump light via the Kerr nonlinearity of the material. The spacing in between the lines of the frequency comb is close to the free spectral range of the resonator, which is 190 GHz for the resonator used. By tuning the pump laser through the resonance and modulating the power of the pump light we can achieve a stable state with a pulsed-shape waveform circulating inside the microresonator. These states are known as dissipative Kerr soliton states and they are solutions to the Lugiato-Lefever equation, which describes the nonlinear physics of the system. So far they had been experimentally demonstrated in fiber-ring cavities as well as crystalline microresonators. The main benefits of these states for Kerr frequency combs is that they allow for low-noise but broadband frequency combs with low modulation in the spectrum. In our case we report a 3-dB bandwidth of 10THz which is equivalent to sub-30fs pulses inside the resonator. Because of the chosen geometry of the waveguide cross section we also observe an effect which is caused by higher-order dispersion. Higher-order dispersion are terms that describe the dispersion beyond the quadratic group velocity dispersion. In order for dissipative Kerr solitons to form, anomalous group velocity dispersion is required. If higher-order terms are present as well, the soliton can still exist but additional

  15. Generation of Optical Combs in a WGM Resonator from a Bichromatic Pump

    NASA Technical Reports Server (NTRS)

    Strekalov, Dmitry V.; Yu, Nan; Matsko, Andrey B.

    2010-01-01

    Optical combs generated by a monolithic resonator with Kerrmedium can be used in a number of applications, including orbital clocks and frequency standards of extremely high accuracy, such as astronomy, molecular spectroscopy, and the like. The main difficulty of this approach is the relatively high pump power that has to be used in such devices, causing undesired thermorefractive effects, as well as stimulated Raman scattering, and limiting the optical comb quality and utility. In order to overcome this problem, this innovation uses a different approach to excitation of the nonlinear oscillations in a Kerr-nonlinear whispering gallery mode (WGM) resonator and generation of the optical comb. By coupling to the resonator two optical pump frequencies instead of just one, the efficiency of the comb source can be increased considerably. It therefore can operate in a lowerpower regime where the undesirable effects are not present. This process does not have a power threshold; therefore, the new optical component can easily be made strong enough to generate further components, making the optical comb spread in a cascade fashion. Additionally, the comb spacing can be made in an arbitrary number of the resonator free spectral ranges (FSR). The experimental setup for this innovation used a fluorite resonator with OMEGA= 13.56 GHz. This material has very low dispersion at the wavelength of 1.5 microns, so the resonator spectrum around this wavelength is highly equidistant. Light was coupled in and out of the resonator using two optical fibers polished at the optimal coupling angle. The gap between the resonator and the fibers, affecting the light coupling and the resonator loading, was controlled by piezo positioners. The light from the input fiber that did not go into the resonator reflected off of its rim, and was collected by a photodetector. This enabled observation and measurement of the (absorption) spectrum of the resonator. The input fiber combined light from two

  16. Spectral self-imaging of time-periodic coherent frequency combs by parabolic cross-phase modulation.

    PubMed

    Maram, Reza; Azaña, José

    2013-11-18

    Integer and fractional spectral self-imaging effects are induced on infinite-duration periodic frequency combs (probe signal) using cross-phase modulation (XPM) with a parabolic pulse train as pump signal. Free-spectral-range tuning (fractional effects) or wavelength-shifting (integer effects) of the frequency comb can be achieved by changing the parabolic pulse peak power or/and repetition rate without affecting the spectral envelope shape and bandwidth of the original comb. For design purposes, we derive the complete family of different pump signals that allow implementing a desired spectral self-imaging process. Numerical simulation results validate our theoretical analysis. We also investigate the detrimental influence of group-delay walk-off and deviations in the nominal temporal shape or power of the pump pulses on the generated output frequency combs. PMID:24514395

  17. Measurement of the carrier envelope offset frequency of a femtosecond frequency comb using a Fabry—Perot interferometer

    NASA Astrophysics Data System (ADS)

    Basnak, D. V.; Bikmukhametov, K. A.; Dmitriev, Aleksandr K.; Dmitrieva, N. I.; Lugovoi, A. A.; Pokasov, P. V.; Chepurov, S. V.

    2010-10-01

    A method for measuring the carrier envelope offset (CEO) frequency of the femtosecond frequency comb with a bandwidth of less than one octave by using a Fabry—Perot interferometer is proposed and experimentally demonstrated.

  18. Tuneable dual-comb spectrometer based on commercial femtosecond lasers and reference cell for optical frequency calibration

    NASA Astrophysics Data System (ADS)

    Portuondo-Campa, E.; Bennès, J.; Balet, L.; Kundermann, S.; Merenda, F.; Boer, G.; Lecomte, S.

    2016-07-01

    Two commercial femtosecond laser sources have been used to implement a dual-comb spectrometer tuneable across a spectral range from 1.5 to 2.2 μm. The optical linewidth of the comb modes was characterized for different time scales in order to estimate the achievable spectral resolution for an optimal acquisition time. The transmission spectra of three different gas samples were recorded, demonstrating good agreement with reference data. Frequency axis calibration was provided via the parallel monitoring of a reference sample. This technique allows an accurate calibration of the frequency axis of the spectrometer, with no need for stabilization or optical referencing of the frequency combs. Our set-up represents a good compromise for a compact and versatile dual-comb spectrometer based on commercially available parts with possible applications in trace-gas monitoring, remote sensing and spectroscopy of short-lived processes.

  19. Single envelope equation modeling of multi-octave comb arrays in microresonators with quadratic and cubic nonlinearities

    NASA Astrophysics Data System (ADS)

    Hansson, Tobias; Leo, François; Erkintalo, Miro; Anthony, Jessienta; Coen, Stéphane; Ricciardi, Iolanda; De Rosa, Maurizio; Wabnitz, Stefan

    2016-06-01

    We numerically study, by means of the single envelope equation, the generation of optical frequency combs ranging from the visible to the mid-infrared spectral regions in resonators with quadratic and cubic nonlinearities. Phase-matched quadratic wave-mixing processes among the comb lines can be activated by low-power continuous wave pumping in the near infrared of a radially poled lithium niobate whispering gallery resonator (WGR). We examine both separate and co-existing intra-cavity doubly resonant second-harmonic generation and parametric oscillation processes, and find that modulation instabilities may lead to the formation of coupled comb arrays extending over multiple octaves. In the temporal domain, the frequency combs may correspond to pulse trains, or isolated pulses.

  20. Measurement of the carrier envelope offset frequency of a femtosecond frequency comb using a Fabry-Perot interferometer

    SciTech Connect

    Basnak, D V; Bikmukhametov, K A; Dmitrieva, N I; Dmitriev, Aleksandr K; Lugovoi, A A; Pokasov, P V; Chepurov, S V

    2010-10-15

    A method for measuring the carrier envelope offset (CEO) frequency of the femtosecond frequency comb with a bandwidth of less than one octave by using a Fabry-Perot interferometer is proposed and experimentally demonstrated. (laser components)

  1. Sex tourism in Thailand.

    PubMed

    Van Kerkwijk, C

    1992-01-01

    Many foreigners visit Thailand in search of sex. While long-distance tourism was long enjoyed by members of more privileged social classes, even the lower economical classes of Japan, Malaysia, Europe, America, and Australia can now afford to travel over long distances. This relatively new breed of tourist is more likely to be of lower socioeconomic and educational status and less likely to use condoms when having sex. An estimated 30,000 sex workers are active in Bangkok, of whom 7000/10,000 are females who work specifically in the tourism sector. 1/2-1/3 of the 600 commercial sex establishments in the city are visited by foreigners. Phuket, Pattaya, Koh Samui, and Chiangmai are also well-frequented by sex tourists. Overall, a large, diverse, inexpensive, and accessible commercial sex market exists in Thailand. One may meet sex workers quasi-ubiquitously and be assured to find someone capable of meeting one's sexual needs. With these attributes, Thailand strongly attracts tourists in search of sex. A certain degree of recklessness also prevails among those on vacation. Away from the peers and social mores of their native lands, tourists may engage in sexually activities without criticism. Likewise, Thai sex workers who cater to foreigners, especially females, enjoy more freedom and control in sexual relations than their peers who work among nationals. Neither single nor married women in Thailand are allowed much sexual freedom and are traditionally expected to be obliging docile, and submissive. The greater than normal personal latitude enjoyed by both sex worker and foreigner lead to more negotiation on condom use and overall lower use. As such, Thailand's commercial sex market with foreigners' involvement therein threatens to spread HIV to many other countries throughout the world. PMID:12286018

  2. Patterns of comb row development in young and adult stages of the ctenophores Mnemiopsis leidyi and Pleurobrachia pileus.

    PubMed

    Tamm, Sidney L

    2012-09-01

    The development of comb rows in larval and adult Mnemiopsis leidyi and adult Pleurobrachia pileus is compared to regeneration of comb plates in these ctenophores. Late gastrula embryos and recently hatched cydippid larvae of Mnemiopsis have five comb plates in subsagittal rows and six comb plates in subtentacular rows. Subsagittal rows develop a new (sixth) comb plate and both types of rows add plates at similar rates until larvae reach the transition to the lobate form at ∼5 mm size. New plate formation then accelerates in subsagittal rows that later extend on the growing oral lobes to become twice the length of subtentacular rows. Interplate ciliated grooves (ICGs) develop in an aboral-oral direction along comb rows, but ICG formation itself proceeds from oral to aboral between plates. New comb plates in Mnemiopsis larvae are added at both aboral and oral ends of rows. At aboral ends, new plates arise as during regeneration: local widening of a ciliated groove followed by formation of a short split plate that grows longer and wider and joins into a common plate. At oral ends, new plates arise as a single tuft of cilia before an ICG appears. Adult Mnemiopsis continue to make new plates at both ends of rows. The frequency of new aboral plate formation varies in the eight rows of an animal and seems unrelated to body size. In Pleurobrachia that lack ICGs, new comb plates at aboral ends arise between the first and second plates as a single small nonsplit plate, located either on the row midline or off-axis toward the subtentacular plane. As the new (now second) plate grows larger, its distance from the first and third plates increases. Size of the new second plate varies within the eight rows of the same animal, indicating asynchronous formation of plates as in Mnemiopsis. New oral plates arise as in Mnemiopsis. The different modes of comb plate formation in Mnemiopsis versus Pleurobrachia are accounted for by differences in mesogleal firmness and mechanisms of

  3. Measurement of carrier envelope offset frequency for a 10 GHz etalon-stabilized semiconductor optical frequency comb

    NASA Astrophysics Data System (ADS)

    Akbulut, M.; Davila-Rodriguez, J.; Ozdur, I.; Quinlan, F.; Ozharar, S.; Hoghooghi, N.; Delfyett, P. J.

    2011-08-01

    We report Carrier Envelope Offset (CEO) frequency measurements of a 10 GHz harmonically mode-locked, Fabry-Perot etalon-stabilized, semiconductor optical frequency comb source. A modified multi-heterodyne mixing technique with a reference frequency comb was utilized for the measurement. Also, preliminary results from an attempt at f-2f self-referencing measurement are presented. The CEO frequency was found to be ~1.47 GHz for the particular etalon that was used.

  4. Generation of Flat Optical Frequency Comb based on Mach-Zehnder Modulator and Recirculating Frequency Shifter Loop

    NASA Astrophysics Data System (ADS)

    Wu, Shibao; Li, Yulong; Fei, Yue; Hu, Faze

    2014-06-01

    We propose a novel scheme to generate optical frequency comb by using Mach-Zehnder modulator and recirculating frequency shifter loop based on IQ modulator driven by radio frequency clock signals. A system of 4 flat and stable comb lines generation based on Mach-Zehnder modulator is set as the seed light source of the recirculating loop. Through theorical analysis and simulation it is shown that the proposed theoretical model is proved in good agreement with simulation results.

  5. Advocating Elementary Sex Education.

    ERIC Educational Resources Information Center

    McNab, Warren L.

    1981-01-01

    Sex education is an important asset to personal growth during the elementary years. Though many parents are opposed to sex education during these early years, sexual knowledge acts as an antidote to fear and does not contribute to promiscuity. New programs in sexuality and family life are presently being developed. (JN)

  6. Sex Away from Home

    ERIC Educational Resources Information Center

    Greenwald, Harold

    1971-01-01

    The reasons why people who are normally truthful to their spouses engage in sex away from home are discussed. These reasons can include loneliness, ego building or the opportunity to have homosexual relations. Sex away from home is likely to increase since the number of people traveling is increasing. (Author/CG)

  7. Single-Sex Classrooms

    ERIC Educational Resources Information Center

    Protheroe, Nancy

    2009-01-01

    Although single-sex education was once the norm in the U.S., the practice has largely been confined to private schools for more than a century. However, with the introduction of the final version of the U.S. Department of Education's so-called single-sex regulations in 2006, public schools were allowed greater flexibility to offer single-sex…

  8. Sex and America's Teenagers.

    ERIC Educational Resources Information Center

    Alan Guttmacher Inst., New York, NY.

    Although sexual activity is common among teenagers, it is not as widespread, and does not begin as early, as most adults believe. This report provides detailed data and analysis of sex among adolescents. Adolescent sexual activity is grouped in ten categories: (1) Rites of passage; (2) The context of adolescents' lives; (3) Sex among teenagers;…

  9. Sex Education Materials.

    ERIC Educational Resources Information Center

    Singer-Magdoff, Laura

    1969-01-01

    After briefly discussing the philosophy of sex education and appraising generally the nature of the instructional methods and materials currently in use in the schools, the author provides brief but incisive reviews of a number of films, filmstrips, and other instructional materials dealing with sex. The reviews are continued in the succeeding…

  10. Sex Determination in Papaya

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Sex determination is an intriguing system in trioecious papaya. Over the past seven decades various hypotheses, based on the knowledge and information available at the time, have been proposed to explain the genetics of the papaya's sex determination. These include a single gene with three alleles...

  11. Sex differences in stroke

    PubMed Central

    Haast, Roy A M; Gustafson, Deborah R; Kiliaan, Amanda J

    2012-01-01

    Sex differences in stroke are observed across epidemiologic studies, pathophysiology, treatments, and outcomes. These sex differences have profound implications for effective prevention and treatment and are the focus of this review. Epidemiologic studies reveal a clear age-by-sex interaction in stroke prevalence, incidence, and mortality. While premenopausal women experience fewer strokes than men of comparable age, stroke rates increase among postmenopausal women compared with age-matched men. This postmenopausal phenomenon, in combination with living longer, are reasons for women being older at stroke onset and suffering more severe strokes. Thus, a primary focus of stroke prevention has been based on sex steroid hormone-dependent mechanisms. Sex hormones affect different (patho)physiologic functions of the cerebral circulation. Clarifying the impact of sex hormones on cerebral vasculature using suitable animal models is essential to elucidate male–female differences in stroke pathophysiology and development of sex-specific treatments. Much remains to be learned about sex differences in stroke as anatomic and genetic factors may also contribute, revealing its multifactorial nature. In addition, the aftermath of stroke appears to be more adverse in women than in men, again based on older age at stroke onset, longer prehospital delays, and potentially, differences in treatment. PMID:23032484

  12. Generation of optical frequency combs via four-wave mixing processes for low- and medium-resolution astronomy

    NASA Astrophysics Data System (ADS)

    Zajnulina, M.; Boggio, J. M. Chavez; Böhm, M.; Rieznik, A. A.; Fremberg, T.; Haynes, R.; Roth, M. M.

    2015-07-01

    We investigate the generation of optical frequency combs through a cascade of four-wave mixing processes in nonlinear fibres with optimised parameters. The initial optical field consists of two continuous-wave lasers with frequency separation larger than 40 GHz (312.7 pm at 1531 nm). It propagates through three nonlinear fibres. The first fibre serves to pulse shape the initial sinusoidal-square pulse, while a strong pulse compression down to sub-100 fs takes place in the second fibre which is an amplifying erbium-doped fibre. The last stage is a low-dispersion highly nonlinear fibre where the frequency comb bandwidth is increased and the line intensity is equalised. We model this system using the generalised nonlinear Schrödinger equation and investigate it in terms of fibre lengths, fibre dispersion, laser frequency separation and input powers with the aim to minimise the frequency comb noise. With the support of the numerical results, a frequency comb is experimentally generated, first in the near infra-red and then it is frequency-doubled into the visible spectral range. Using a MUSE-type spectrograph, we evaluate the comb performance for astronomical wavelength calibration in terms of equidistancy of the comb lines and their stability.

  13. Optical-frequency-comb generation and entanglement with low-power optical input in a photonic molecule

    NASA Astrophysics Data System (ADS)

    Li, Jiahua; Yu, Rong; Ding, Chunling; Wang, Wei; Wu, Ying

    2014-09-01

    Optical-frequency combs consisting of equally spaced sharp lines in frequency space have triggered substantial advances in optical-frequency metrology and precision measurements and in applications such as laser-based gas sensing and molecular fingerprinting. Here, we propose a scheme to generate a type of optical-frequency combs and convert them from one cavity to the other in a hybrid optical system composed of a pair of coupled photonic crystal cavities called a photonic molecule (PM) and a single semiconductor quantum dot (QD) embedded in one cavity of the molecule. Optical-frequency combs are formed by the interaction between a cavity mode and a continuous-wave (CW) two-tone driving laser consisting of a pump field and a seed field via QD-induced strong nonlinearity. In this situation, the initial input pump and seed CW lasers can interact among each other and produce optical higher-order sidebands with equal spacing via parametric frequency conversion provided by QD-induced nonlinear optical effects. Using numerical simulations, it is clearly shown that the beat frequency of the two-tone components plays an important role in determining the comb spacing and matched frequency combs can be formed in the PM. We also demonstrate that the present interacting QD-PM system can serve as a platform to generate large-scale quantum entanglement between two comb modes. The results obtained here may be useful for real experiments in a photonic crystal platform.

  14. WDM-CAP-PON integration with VLLC system based on optical frequency comb

    NASA Astrophysics Data System (ADS)

    He, Jing; Dong, Huan; Deng, Rui; Shi, Jin; Chen, Lin

    2016-09-01

    In this paper, a wavelength division multiplexing carrier-less amplitude phase modulation passive optical network (WDM-CAP-PON) integration with visible laser light communication (VLLC) system is proposed and experimentally demonstrated. To reduce the cost of WDM system, the optical frequency comb scheme using one Mach-Zehnder modulator (MZM) is utilized and five flat optical combs can be generated. Meanwhile, a blue laser diode (LD) as a VLLC optical source can provide high data rate and long transmission distance. Utilizing overlap frequency domain equalization (OFDE) and negative chirp of MZM, the system performance in both Q-factor and receiver sensitivity can be improved. After 20 km standard single mode fiber (SSMF) and 4.5 m free space transmission, the experimental results show that 10 Gb/s CAP signal can be achieved under 7% forward error correction (FEC) limit of 3 . 8 × 10-3.

  15. Laser Frequency Comb Supported Stellar Radial Velocity Determination in the NIR: Initial Results.

    NASA Astrophysics Data System (ADS)

    Osterman, Steve; Diddams, S.; Quinlan, F.; Ycas, G.; Mahadevan, S.; Ramsey, L.; Bender, C.; Terrien, R.; Botzer, B.; Redman, S.

    2011-09-01

    The laser frequency comb presents the potential for a revolutionary increase in radial velocity precision by providing a calibration reference of unprecedented quality in terms of wavelength knowledge, repeatability, number, density and regularity of lines. Promising first steps have been taken leading to the derivation of stellar radial velocities in the NIR H band, a wavelength range well suited to the observation of M dwarfs. These stars, with low mass and low luminosity, are the most prevalent class of stars within 10 parsecs and can be expected to yield a higher reflex velocity for a terrestrial mass planet in the liquid water habitable zone than would be the case with a more massive star such as our own. We present the design and both laboratory and on-sky performance of an H-band laser frequency comb used in conjunction with the Penn State Pathfinder testbed spectrograph and discuss lessons learned and plans for follow on testing.

  16. Fabry-Pérot filter cavities for wide-spaced frequency combs with large spectral bandwidth

    NASA Astrophysics Data System (ADS)

    Steinmetz, T.; Wilken, T.; Araujo-Hauck, C.; Holzwarth, R.; Hänsch, T. W.; Udem, T.

    2009-08-01

    We use low-finesse Fabry-Pérot cavities in series to generate frequency combs with a large mode spacing in a way that allows its application to a large optical bandwidth. The attenuation of laser modes closest to the pass bands of the cavity exceeds 70 dB for a filter ratio of m=20 relative to the resonant modes centered within the pass bands. We also identify the best cavity geometry to suppress spurious transmission of higher order transversal modes. Such a thinned out frequency comb can be used to calibrate traditional spectrographs for precision astronomy. In the time domain mode filtering generates a pulse train with a multiplied repetition rate. High-fidelity filtering, as described here, implies small variations of the pulse energies.

  17. First Stellar Radial Velocities with a Laser Frequency Comb: Observations in the NIR H Band

    NASA Astrophysics Data System (ADS)

    Osterman, Steve; Diddams, S.; Quinlan, F.; Ycas, G.; Mahadevan, S.; Ramsey, L.; Bender, C.; Redman, S.; Terrien, R.; Botzer, B.

    2011-01-01

    Advances in high precision radial velocity spectroscopy have been hindered by the lack of suitable wavelength references. This has been especially the case in the infrared where until recently radial velocity precision has been limited to 50-100m/s, hindering investigations such as the search for extrasolar planets orbiting cooler M stars at these wavelengths. To redress deficiency this we have developed a 25GHz laser frequency comb spanning the H band and suitable for use with spectrographs with spectral resolution in the range of 40,000 - 60,000, with RV precision limited by instrument stability and object S/N rather than by the lack of a suitable wavelength standard. We will present CU/NIST frequency comb performance and results obtained using the Pennsylvania State University's Pathfinder Spectrograph on the Hobby Eberly Telescope and will discuss lessons learned.

  18. Study on high coupling efficiency Er-doped fiber laser for femtosecond optical frequency comb

    NASA Astrophysics Data System (ADS)

    Pang, Lihui; Liu, Wenjun; Han, Hainian; Wei, Zhiyi

    2016-09-01

    The femtosecond laser is crucial to the operation of the femtosecond optical frequency comb. In this paper, a passively mode-locked erbium-doped fiber laser is presented with 91.4 fs pulse width and 100.8 MHz repetition rate, making use of the nonlinear polarized evolution effect. Using a 976 nm pump laser diode, the average output power is 16 mW from the coupler and 27 mW from the polarization beam splitter at the pump power of 700 mW. The proposed fiber laser can offer excellent temporal purity in generated pulses with high power, and provide a robust source for fiber-based frequency combs and supercontinuum generation well suited for industrial applications.

  19. Hierarchical, multilayered cell walls reinforced by recycled silk cocoons enhance the structural integrity of honeybee combs

    PubMed Central

    Zhang, Kai; Duan, Huiling; Karihaloo, Bhushan L.; Wang, Jianxiang

    2010-01-01

    We reveal the sophisticated and hierarchical structure of honeybee combs and measure the elastic properties of fresh and old natural honeycombs at different scales by optical microscope, environmental scanning electron microscope, nano/microindentation, and by tension and shear tests. We demonstrate that the comb walls are continuously strengthened and stiffened without becoming fragile by the addition of thin wax layers reinforced by recycled silk cocoons reminiscent of modern fiber-reinforced composite laminates. This is done to increase its margin of safety against collapse due to a temperature increase. Artificial engineering honeycombs mimic only the macroscopic geometry of natural honeycombs, but have yet to achieve the microstructural sophistication of their natural counterparts. The natural honeycombs serve as a prototype of truly biomimetic cellular materials with hitherto unattainable improvement in stiffness, strength, toughness, and thermal stability. PMID:20439765

  20. Two-Photon Frequency Comb Excitation of Rubidium Atoms in External Magnetic Field

    NASA Astrophysics Data System (ADS)

    Vujičić, N.; Ban, T.; Skenderović, H.; Vdović, S.; Pichler, G.

    2008-10-01

    In the present experiment the 5S-5D two-photon transitions in 85Rb and 87Rb atoms as a result of the interaction of the femtosecond frequency comb with atomic levels of both rubidium isotopes are investigated. The main problem in studying of two-photon transitions is in optimization of the excitation efficiency of the desired state. There are two general cases: those transition with an intermediate resonance those in which the pulse spectrum is far detuned from an intermediate resonance. In order to investigate the dependence of the two-photon fluorescence signal as a result of interaction of the frequency comb with perturbed energy-level pattern an external magnetic field was applied.

  1. Adaptive frequency comb illumination for interferometry in the case of nested two-beam cavities

    SciTech Connect

    Harder, Irina; Leuchs, Gerd; Mantel, Klaus; Schwider, Johannes

    2011-09-01

    The homogeneity test of glass plates in a Fizeau interferometer is hampered by the superposition of multiple interference signals coming from the surfaces of the glass plate as well as the empty Fizeau cavity. To evaluate interferograms resulting from such nested cavities, various approaches such as the use of broadband light sources have been applied. In this paper, we propose an adaptive frequency comb interferometer to accomplish the cavity selection. An adjustable Fabry-Perot resonator is used to generate a variable frequency comb that can be matched to the length of the desired cavity. Owing to its flexibility, the number of measurements needed for the homogeneity test can be reduced to four. Furthermore, compared to approaches using a two-beam interferometer as a filter for the broadband light source, the visibility of the fringe system is considerably higher if a Fabry-Perot filter is applied.

  2. Transmission comb of a distributed Bragg reflector with two surface dielectric gratings

    NASA Astrophysics Data System (ADS)

    Zhao, Xiaobo; Zhang, Yongyou; Zhang, Qingyun; Zou, Bingsuo; Schwingenschlogl, Udo

    2016-02-01

    The transmission behaviour of a distributed Bragg reector (DBR) with surface dielectric gratings on top and bottom is studied. The transmission shows a comb-like spectrum in the DBR band gap, which is explained in the Fano picture. The number density of the transmission peaks increases with increasing number of cells of the DBR, while the ratio of the average full width at half maximum to the corresponding average free spectral range, being only few percent for both transversal electric and magnetic waves, is almost invariant. The transmission peaks can be narrower than 0.1 nm and are fully separated from each other in certain wavebands. We further prove that the transmission combs are robust against randomness in the heights of the DBR layers. Therefore, the proposed structure is a candidate for an ultra-narrow-band multichannel filter or polarizer.

  3. a New Broadband Cavity Enhanced Frequency Comb Spectroscopy Technique Using GHz Vernier Filtering.

    NASA Astrophysics Data System (ADS)

    Morville, Jérôme; Rutkowski, Lucile; Dobrev, Georgi; Crozet, Patrick

    2015-06-01

    We present a new approach to Cavity Enhanced - Direct Frequency Comb Spectroscopy where the full emission bandwidth of a Titanium:Sapphire laser is exploited at GHz resolution. The technique is based on a low-resolution Vernier filtering obtained with an appreciable -actively stabilized- mismatch between the cavity Free Spectral Range and the laser repetition rate, using a diffraction grating and a split-photodiode. This particular approach provides an immunity to frequency-amplitude noise conversion, reaching an absorption baseline noise in the 10-9 cm-1 range with a cavity finesse of only 3000. Spectra covering 1800 cm-1 (˜ 55 THz) are acquired in recording times of about 1 second, providing an absorption figure of merit of a few 10-11 cm-1/√{Hz}. Initially tested with ambient air, we report progress in using the Vernier frequency comb method with a discharge source of small radicals. Rutkowski et al, Opt. Lett., 39(23)2014

  4. Fully referenced single-comb interferometry using optical sampling by laser-cavity tuning.

    PubMed

    Potvin, Simon; Boudreau, Sylvain; Deschênes, Jean-Daniel; Genest, Jérôme

    2013-01-10

    The correction of setup and laser instabilities in a single-comb interferometric measurement using optical sampling by laser-cavity tuning is investigated. A two-reference solution that allows full correction of the interferogram is presented. The technique is compared to a slightly simpler one-reference correction. For the one-reference case, all the subtleties involved in this partial correction and the dependence between the achievable measurement accuracy and the setup parameters are highlighted. The parameters considered are the comb bandwidth, the laser-frequency noise, the required spectral resolution, the cavity scan speed, and the length of the delay line. For both referencing approaches, experimental results using a fiber delay line of 10 km and a 100 MHz mode-locked laser with its repetition rate swept at 500 Hz are shown. PMID:23314642

  5. Excluded-volume interaction induced stiffness of comb polymer with densely grafted side-chains

    NASA Astrophysics Data System (ADS)

    Qiu, Feng

    2014-03-01

    Excluded-volume interaction has been widely recognized to cause expansion of polymer chain at large length scale. However, its effect on chain conformations at small length scale has been studied to less extent. Here we consider a comb polymer with its backbone densely grafted by side-chains as a model system. The method analogue to solving the electrostatic persistence length problem for either rigid or flexible polyelectrolytes is employed. For comb polymers with rigid backbone near the rod limit, the excluded-volume interaction induced persistence length scales linearly with the volume of the side-chain. While for flexible backbone, the persistence length depends on the side-chain volume more weakly. Field theoretic method that is relevant to address this problem is also explored and discussed. Work supported by NSFC.

  6. Optical properties of the iridescent organ of the comb-jellyfish Beroë cucumis (Ctenophora)

    NASA Astrophysics Data System (ADS)

    Welch, Victoria; Vigneron, Jean Pol; Lousse, Virginie; Parker, Andrew

    2006-04-01

    Using transmission electron microscopy, analytical modeling, and detailed numerical simulations, the iridescence observed from the comb rows of the ctenophore Beroë cucumis was investigated. It is shown that the changing coloration which accompanies the beating of comb rows as the animal swims can be explained by the weakly-contrasted structure of the refractive index induced by the very coherent packing of locomotory cilia. The colors arising from the narrow band-gap reflection are shown to be highly saturated and, as a function of the incidence angle, cover a wide range of the visible and ultraviolet spectrum. The high transparency of the structure at the maximal bioluminescence wavelength is also explained.

  7. Phase noise analysis of injected gain switched comb source for coherent communications.

    PubMed

    Zhou, Rui; Huynh, Tam N; Vujicic, Vidak; Anandarajah, Prince M; Barry, Liam P

    2014-04-01

    We present experimentally and analytically the phase noise characterization of an externally injected gain switched comb source. The results reveal the residual high frequency FM noise in the comb lines, which stays unnoticed in the optical linewidth value but leads to an increased phase-error variance. The potential impact of the residual phase noise is investigated in a 10.7 GBaud optical DQPSK system where a 2 dB power penalty is recorded at BER of 10(-9). In a 10.7 GBaud digital coherent QPSK system no penalty is observed but with 5 GBaud 16-QAM format a 3 dBpenalty exists at the FEC limit of 4.4e-3. PMID:24718188

  8. Self referenced Yb-fiber-laser frequency comb using a dispersion micromanaged tapered holey fiber.

    PubMed

    Pal, Parama; Knox, Wayne H; Hartl, Ingmar; Fermann, Martin E

    2007-09-17

    We demonstrate a fully stabilized frequency comb in the 1mum spectral region based on an Yb-fiber oscillator and a cladding pumped chirped pulse Yb-fiber amplifier whose output is spectrally broadened in a dispersion micromanaged holey fiber. The dispersion micromanaged fiber is used to generate efficient, low noise spectral components at 523nm which are heterodyned with the second harmonic of the amplifier output for standard f-to-2f self-referenced carrier envelope offset frequency detection. For comb stabilization we phase-lock this offset frequency and the oscillator repetition frequency simultaneously to an RF reference by feedback controlling the oscillator pump diode current and the driving voltage of an intracavity piezo-electric fiber stretcher respectively. PMID:19547582

  9. Tapered semiconductor amplifiers for optical frequency combs in the near infrared.

    PubMed

    Cruz, Flavio C; Stowe, Matthew C; Ye, Jun

    2006-05-01

    A tapered semiconductor amplifier is injection seeded by a femtosecond optical frequency comb at 780 nm from a mode-locked Ti:sapphire laser. Energy gains of more than 17 dB(12 dB) are obtained for 1 mW(20 mW) of average input power when the input pulses are stretched into the picosecond range. A spectral window of supercontinuum light generated in a photonic fiber has also been amplified. Interferometric measurements show sub-Hertz linewidths for a heterodyne beat between the input and amplified comb components, yielding no detectable phase-noise degradation under amplification. These amplifiers can be used to boost the infrared power in f-to-2f interferometers used to determine the carrier-to-envelope offset frequency, with clear advantages for stabilization of octave-spanning femtosecond lasers and other supercontinuum light sources. PMID:16642104

  10. Resonant light scattering of a laser frequency comb by a quantum dot

    NASA Astrophysics Data System (ADS)

    Konthasinghe, K.; Peiris, M.; Muller, A.

    2014-08-01

    We investigate the spectral and temporal properties of light scattered near resonantly by a single quantum dot when the incident laser field is a frequency comb consisting of a superposition of monochromatic waves equidistant in frequency. Such fields encompass those generated by, e.g., a periodically pulsed laser. A general theoretical treatment for the calculation of first- and second-order correlation functions is given which takes account of spectral diffusion through a slowly varying detuning from resonance, permitting accurate comparison with experiments. We explore the two distinct regimes in which the frequency-comb separation is either larger or smaller than the radiative decay rate. We verify the validity of our calculations by a comparison with experimental data for the case of a bichromatic field and discuss the manifestation of phase coherence between the incoming field and the scattered single-photon wave packet.

  11. A Laser Frequency Comb System for Absolute Calibration of the VTT Echelle Spectrograph

    NASA Astrophysics Data System (ADS)

    Doerr, H.-P.; Steinmetz, T.; Holzwarth, R.; Kentischer, T.; Schmidt, W.

    2012-10-01

    A wavelength calibration system based on a laser frequency comb (LFC) was developed in a co-operation between the Kiepenheuer-Institut für Sonnenphysik, Freiburg, Germany and the Max-Planck-Institut für Quantenoptik, Garching, Germany for permanent installation at the German Vacuum Tower Telescope (VTT) on Tenerife, Canary Islands. The system was installed successfully in October 2011. By simultaneously recording the spectra from the Sun and the LFC, for each exposure a calibration curve can be derived from the known frequencies of the comb modes that is suitable for absolute calibration at the meters per second level. We briefly summarize some topics in solar physics that benefit from absolute spectroscopy and point out the advantages of LFC compared to traditional calibration techniques. We also sketch the basic setup of the VTT calibration system and its integration with the existing echelle spectrograph.

  12. Performance of a laser frequency comb calibration system with a high-resolution solar echelle spectrograph

    NASA Astrophysics Data System (ADS)

    Doerr, H.-P.; Kentischer, T. J.; Steinmetz, T.; Probst, R. A.; Franz, M.; Holzwarth, R.; Udem, Th.; Hänsch, T. W.; Schmidt, W.

    2012-09-01

    Laser frequency combs (LFC) provide a direct link between the radio frequency (RF) and the optical frequency regime. The comb-like spectrum of an LFC is formed by exact equidistant laser modes, whose absolute optical frequencies are controlled by RF-references such as atomic clocks or GPS receivers. While nowadays LFCs are routinely used in metrological and spectroscopic fields, their application in astronomy was delayed until recently when systems became available with a mode spacing and wavelength coverage suitable for calibration of astronomical spectrographs. We developed a LFC based calibration system for the high-resolution echelle spectrograph at the German Vacuum Tower Telescope (VTT), located at the Teide observatory, Tenerife, Canary Islands. To characterize the calibration performance of the instrument, we use an all-fiber setup where sunlight and calibration light are fed to the spectrograph by the same single-mode fiber, eliminating systematic effects related to variable grating illumination.

  13. Dimensional metrology using the optical comb of a mode-locked laser

    NASA Astrophysics Data System (ADS)

    Jin, Jonghan

    2016-02-01

    In the field of dimensional metrology, significant technical challenges have been encountered with regard to large-scale object assembly, satellite positioning, control of the long-distance precision stage, and inspections of large steps or deep holes on semiconductor devices and multi-layered display panels. The key elements required are high speeds, a long dynamic measurable range, and good precision of measurements, and conventional methods can scarcely meet such requirements simultaneously. Promisingly, the advent of the optical comb has opened up numerous possibilities to break through practical limits by exploiting several of its unique features. These include inter-mode interference, a wide spectral bandwidth with a long coherence length and well-defined longitudinal modes. In this review, various dimensional metrological methods using the optical comb are introduced, describing their basic principles and applications in scientific as well as industrial areas.

  14. Dual-pump Kerr Micro-cavity Optical Frequency Comb with varying FSR spacing.

    PubMed

    Wang, Weiqiang; Chu, Sai T; Little, Brent E; Pasquazi, Alessia; Wang, Yishan; Wang, Leiran; Zhang, Wenfu; Wang, Lei; Hu, Xiaohong; Wang, Guoxi; Hu, Hui; Su, Yulong; Li, Feitao; Liu, Yuanshan; Zhao, Wei

    2016-01-01

    In this paper, we demonstrate a novel dual-pump approach to generate robust optical frequency comb with varying free spectral range (FSR) spacing in a CMOS-compatible high-Q micro-ring resonator (MRR). The frequency spacing of the comb can be tuned by an integer number FSR of the MRR freely in our dual-pump scheme. The dual pumps are self-oscillated in the laser cavity loop and their wavelengths can be tuned flexibly by programming the tunable filter embedded in the cavity. By tuning the pump wavelength, broadband OFC with the bandwidth of >180 nm and the frequency-spacing varying from 6 to 46-fold FSRs is realized at a low pump power. This approach could find potential and practical applications in many areas, such as optical metrology, optical communication, and signal processing systems, for its excellent flexibility and robustness. PMID:27338250

  15. Generation and photonic guidance of multi-octave optical-frequency combs.

    PubMed

    Couny, F; Benabid, F; Roberts, P J; Light, P S; Raymer, M G

    2007-11-16

    Ultrabroad coherent comb-like optical spectra spanning several octaves are a chief ingredient in the emerging field of attoscience. We demonstrate generation and guidance of a three-octave spectral comb, spanning wavelengths from 325 to 2300 nanometers, in a hydrogen-filled hollow-core photonic crystal fiber. The waveguidance results not from a photonic band gap but from the inhibited coupling between the core and cladding modes. The spectrum consists of up to 45 high-order Stokes and anti-Stokes lines and is generated by driving the confined gas with a single, moderately powerful (10-kilowatt) infrared laser, producing 12-nanosecond-duration pulses. This represents a reduction by six orders of magnitude in the required laser powers over previous equivalent techniques and opens up a robust and much simplified route to synthesizing attosecond pulses. PMID:18006741

  16. Transmission comb of a distributed Bragg reflector with two surface dielectric gratings.

    PubMed

    Zhao, Xiaobo; Zhang, Yongyou; Zhang, Qingyun; Zou, Bingsuo; Schwingenschlogl, Udo

    2016-01-01

    The transmission behaviour of a distributed Bragg reector (DBR) with surface dielectric gratings on top and bottom is studied. The transmission shows a comb-like spectrum in the DBR band gap, which is explained in the Fano picture. The number density of the transmission peaks increases with increasing number of cells of the DBR, while the ratio of the average full width at half maximum to the corresponding average free spectral range, being only few percent for both transversal electric and magnetic waves, is almost invariant. The transmission peaks can be narrower than 0.1 nm and are fully separated from each other in certain wavebands. We further prove that the transmission combs are robust against randomness in the heights of the DBR layers. Therefore, the proposed structure is a candidate for an ultra-narrow-band multichannel filter or polarizer. PMID:26893069

  17. Transmission comb of a distributed Bragg reflector with two surface dielectric gratings

    PubMed Central

    Zhao, Xiaobo; Zhang, Yongyou; Zhang, Qingyun; Zou, Bingsuo; Schwingenschlogl, Udo

    2016-01-01

    The transmission behaviour of a distributed Bragg reector (DBR) with surface dielectric gratings on top and bottom is studied. The transmission shows a comb-like spectrum in the DBR band gap, which is explained in the Fano picture. The number density of the transmission peaks increases with increasing number of cells of the DBR, while the ratio of the average full width at half maximum to the corresponding average free spectral range, being only few percent for both transversal electric and magnetic waves, is almost invariant. The transmission peaks can be narrower than 0.1 nm and are fully separated from each other in certain wavebands. We further prove that the transmission combs are robust against randomness in the heights of the DBR layers. Therefore, the proposed structure is a candidate for an ultra-narrow-band multichannel filter or polarizer. PMID:26893069

  18. Performance estimation of dual-comb spectroscopy in different frequency-control schemes.

    PubMed

    Yang, Honglei; Wei, Haoyun; Zhang, Hongyuan; Chen, Kun; Li, Yan; Smolski, Viktor O; Vodopyanov, Konstantin L

    2016-08-10

    Dual-comb spectroscopy (DCS) has shown unparalleled advantages but at the cost of highly mutual coherence between comb lasers. Here, we investigate spectral degradation induced by laser frequency instabilities and improvement benefited from active laser stabilization. Mathematical models of DCS in the cases of direct radio-frequency (RF) locking and optical phase stabilization were separately established first. Numerical simulations are utilized to study the impact of laser intrinsic stability and the improvement by different locking strategies on spectral performance in the following. Finally, both simulations are proven by corresponding experiments. It shows that an optically phase-stabilized system owns a better immunity of laser frequency fluctuations than a direct RF-stabilized one. Furthermore, the performance improvement by the feedback servos is also more effective in the optically phase-stabilized system. In addition, the simulations could instruct optimal design and system improvement. PMID:27534474

  19. Generation of multiphoton entangled quantum states by means of integrated frequency combs.

    PubMed

    Reimer, Christian; Kues, Michael; Roztocki, Piotr; Wetzel, Benjamin; Grazioso, Fabio; Little, Brent E; Chu, Sai T; Johnston, Tudor; Bromberg, Yaron; Caspani, Lucia; Moss, David J; Morandotti, Roberto

    2016-03-11

    Complex optical photon states with entanglement shared among several modes are critical to improving our fundamental understanding of quantum mechanics and have applications for quantum information processing, imaging, and microscopy. We demonstrate that optical integrated Kerr frequency combs can be used to generate several bi- and multiphoton entangled qubits, with direct applications for quantum communication and computation. Our method is compatible with contemporary fiber and quantum memory infrastructures and with chip-scale semiconductor technology, enabling compact, low-cost, and scalable implementations. The exploitation of integrated Kerr frequency combs, with their ability to generate multiple, customizable, and complex quantum states, can provide a scalable, practical, and compact platform for quantum technologies. PMID:26965623

  20. Novel active comb-shaped dry electrode for EEG measurement in hairy site.

    PubMed

    Huang, Yan-Jun; Wu, Chung-Yu; Wong, Alice May-Kuen; Lin, Bor-Shyh

    2015-01-01

    Electroencephalography (EEG) is an important biopotential, and has been widely applied in clinical applications. The conventional EEG electrode with conductive gels is usually used for measuring EEG. However, the use of conductive gel also encounters with the issue of drying and hardening. Recently, many dry EEG electrodes based on different conductive materials and techniques were proposed to solve the previous issue. However, measuring EEG in the hairy site is still a difficult challenge. In this study, a novel active comb-shaped dry electrode was proposed to measure EEG in hairy site. Different form other comb-shaped or spike-shaped dry electrodes, it can provide more excellent performance of avoiding the signal attenuation, phase distortion, and the reduction of common mode rejection ratio. Even under walking motion, it can effectively acquire EEG in hairy site. Finally, the experiments for alpha rhythm and steady-state visually evoked potential were also tested to validate the proposed electrode. PMID:25137719

  1. Frequency-comb-referenced mid-infrared source for high-precision spectroscopy.

    PubMed

    Peltola, Jari; Vainio, Markku; Fordell, Thomas; Hieta, Tuomas; Merimaa, Mikko; Halonen, Lauri

    2014-12-29

    We report on a tunable continuous-wave mid-infrared optical parametric oscillator (OPO), which is locked to a fully stabilized near-infrared optical frequency comb using a frequency doubling scheme. The OPO is used for 40 GHz mode-hop-free, frequency-comb-locked scans in the wavelength region between 2.7 and 3.4 μm. We demonstrate the applicability of the method to high-precision cavity-ring-down spectroscopy of nitrous oxide (N2O) and water (H2O) at 2.85 µm and of methane (CH4) at 3.2 μm. PMID:25607205

  2. Dual-pump Kerr Micro-cavity Optical Frequency Comb with varying FSR spacing

    PubMed Central

    Wang, Weiqiang; Chu, Sai T.; Little, Brent E.; Pasquazi, Alessia; Wang, Yishan; Wang, Leiran; Zhang, Wenfu; Wang, Lei; Hu, Xiaohong; Wang, Guoxi; Hu, Hui; Su, Yulong; Li, Feitao; Liu, Yuanshan; Zhao, Wei

    2016-01-01

    In this paper, we demonstrate a novel dual-pump approach to generate robust optical frequency comb with varying free spectral range (FSR) spacing in a CMOS-compatible high-Q micro-ring resonator (MRR). The frequency spacing of the comb can be tuned by an integer number FSR of the MRR freely in our dual-pump scheme. The dual pumps are self-oscillated in the laser cavity loop and their wavelengths can be tuned flexibly by programming the tunable filter embedded in the cavity. By tuning the pump wavelength, broadband OFC with the bandwidth of >180 nm and the frequency-spacing varying from 6 to 46-fold FSRs is realized at a low pump power. This approach could find potential and practical applications in many areas, such as optical metrology, optical communication, and signal processing systems, for its excellent flexibility and robustness. PMID:27338250

  3. Photonic chip-based optical frequency comb using soliton Cherenkov radiation.

    PubMed

    Brasch, V; Geiselmann, M; Herr, T; Lihachev, G; Pfeiffer, M H P; Gorodetsky, M L; Kippenberg, T J

    2016-01-22

    Optical solitons are propagating pulses of light that retain their shape because nonlinearity and dispersion balance each other. In the presence of higher-order dispersion, optical solitons can emit dispersive waves via the process of soliton Cherenkov radiation. This process underlies supercontinuum generation and is of critical importance in frequency metrology. Using a continuous wave-pumped, dispersion-engineered, integrated silicon nitride microresonator, we generated continuously circulating temporal dissipative Kerr solitons. The presence of higher-order dispersion led to the emission of red-shifted soliton Cherenkov radiation. The output corresponds to a fully coherent optical frequency comb that spans two-thirds of an octave and whose phase we were able to stabilize to the sub-Hertz level. By preserving coherence over a broad spectral bandwidth, our device offers the opportunity to develop compact on-chip frequency combs for frequency metrology or spectroscopy. PMID:26721682

  4. Frequency-stabilized Yb:fiber comb with a tapered single-mode fiber

    NASA Astrophysics Data System (ADS)

    Yang, Xie; Hai-Nian, Han; Long, Zhang; Zi-Jiao, Yu; Zheng, Zhu; Lei, Hou; Li-Hui, Pang; Zhi-Yi, Wei

    2016-04-01

    We demonstrate a stable Yb:fiber frequency comb with supercontinuum generation by using a specially designed tapered single-mode fiber, in which a spectrum spanning from 500 nm to 1500 nm is produced. The carrier-envelope offset signal of the Yb:fiber comb is measured with a signal-to-noise ratio of more than 40 dB and a linewidth narrower than 120 kHz. The repetition rate and carrier-envelope offset signals are simultaneously phase locked to a microwave reference frequency. Project supported by the National Basic Research Program of China (973 Program) (Grant No. 2012CB821304) and the National Natural Science Foundation of China (Grant No. 61378040).

  5. Impact of dispersion on amplitude and frequency noise in a Yb-fiber laser comb.

    PubMed

    Nugent-Glandorf, Lora; Johnson, Todd A; Kobayashi, Yohei; Diddams, Scott A

    2011-05-01

    We describe a Yb-fiber-based laser comb, with a focus on the relationship between the net-cavity dispersion and frequency noise on the comb. While tuning the net-cavity dispersion from anomalous to normal, we measure the relative intensity noise, offset frequency (f(CEO)) linewidth, and the resulting frequency noise spectrum on the f(CEO). We find that the laser operating at zero net-cavity dispersion has many advantages, including an approximately 100× reduction in free-running f(CEO) linewidth and frequency noise power spectral density when compared to the normal-dispersion regime. At the zero-dispersion point, we demonstrate a phase-locked f(CEO) beat with low residual noise. PMID:21540933

  6. Evanescent-wave comb spectroscopy of liquids with strongly dispersive optical fiber cavities

    NASA Astrophysics Data System (ADS)

    Avino, S.; Giorgini, A.; Salza, M.; Fabian, M.; Gagliardi, G.; De Natale, P.

    2013-05-01

    We demonstrate evanescent-wave fiber cavity-enhanced spectroscopy in the liquid phase using a near-infrared frequency comb. Exploiting strong fiber-dispersion effects, we show that liquid absorption spectra can be recorded without any external dispersive element. The fiber cavity is used both as sensor and spectrometer. The resonance modes are frequency locked to the comb teeth while the cavity photon lifetime is measured over 155 nm, from 1515 nm to 1670 nm, where absorption bands of liquid polyamines are detected as a proof of concept. Our fiber spectrometer lends itself to in situ, real-time chemical analysis in environmental monitoring, biomedical assays, and micro-opto-fluidic systems.

  7. Unified approach to cascaded stimulated Brillouin scattering and frequency-comb generation

    NASA Astrophysics Data System (ADS)

    Dong, Mark; Winful, Herbert G.

    2016-04-01

    We present a unified approach to cascaded stimulated Brillouin scattering and frequency-comb generation in which the multitude of interacting pump, Stokes, and anti-Stokes optical fields is described by a single forward wave and a single backward wave at a single carrier frequency. The envelopes of these two waves are modulated through coupling to a single acoustic oscillation and through four-wave mixing. Starting from a single pump field, we observe the emergence of a comb of frequencies as the intensity is increased. The set of three differential equations derived here is sufficient to describe the generation of any number of Brillouin sidebands in oscillator systems that would have required hundreds of coupled equations in the standard approach. We test this approach on some published experiments and find excellent agreement with the results.

  8. Photonic chip-based optical frequency comb using soliton Cherenkov radiation

    NASA Astrophysics Data System (ADS)

    Brasch, V.; Geiselmann, M.; Herr, T.; Lihachev, G.; Pfeiffer, M. H. P.; Gorodetsky, M. L.; Kippenberg, T. J.

    2016-01-01

    Optical solitons are propagating pulses of light that retain their shape because nonlinearity and dispersion balance each other. In the presence of higher-order dispersion, optical solitons can emit dispersive waves via the process of soliton Cherenkov radiation. This process underlies supercontinuum generation and is of critical importance in frequency metrology. Using a continuous wave-pumped, dispersion-engineered, integrated silicon nitride microresonator, we generated continuously circulating temporal dissipative Kerr solitons. The presence of higher-order dispersion led to the emission of red-shifted soliton Cherenkov radiation. The output corresponds to a fully coherent optical frequency comb that spans two-thirds of an octave and whose phase we were able to stabilize to the sub-Hertz level. By preserving coherence over a broad spectral bandwidth, our device offers the opportunity to develop compact on-chip frequency combs for frequency metrology or spectroscopy.

  9. Sex chromosome drive.

    PubMed

    Helleu, Quentin; Gérard, Pierre R; Montchamp-Moreau, Catherine

    2015-02-01

    Sex chromosome drivers are selfish elements that subvert Mendel's first law of segregation and therefore are overrepresented among the products of meiosis. The sex-biased progeny produced then fuels an extended genetic conflict between the driver and the rest of the genome. Many examples of sex chromosome drive are known, but the occurrence of this phenomenon is probably largely underestimated because of the difficulty to detect it. Remarkably, nearly all sex chromosome drivers are found in two clades, Rodentia and Diptera. Although very little is known about the molecular and cellular mechanisms of drive, epigenetic processes such as chromatin regulation could be involved in many instances. Yet, its evolutionary consequences are far-reaching, from the evolution of mating systems and sex determination to the emergence of new species. PMID:25524548

  10. Sex in Fungi

    PubMed Central

    Ni, Min; Feretzaki, Marianna; Sun, Sheng; Wang, Xuying; Heitman, Joseph

    2012-01-01

    Sexual reproduction enables genetic exchange in eukaryotic organisms as diverse as fungi, animals, plants, and ciliates. Given its ubiquity, sex is thought to have evolved once, possibly concomitant with or shortly after the origin of eukaryotic organisms themselves. The basic principles of sex are conserved, including ploidy changes, the formation of gametes via meiosis, mate recognition, and cell-cell fusion leading to the production of a zygote. Although the basic tenants are shared, sex determination and sexual reproduction occur in myriad forms throughout nature, including outbreeding systems with more than two mating types or sexes, unisexual selfing, and even examples in which organisms switch mating type. As robust and diverse genetic models, fungi provide insights into the molecular nature of sex, sexual specification, and evolution to advance our understanding of sexual reproduction and its impact throughout the eukaryotic tree of life. PMID:21942368

  11. Sex in the flesh.

    PubMed

    Laqueur, Thomas W

    2003-06-01

    This response to Michael Stolberg argues that the occasional piece of evidence for sexual dimorphism in Renaissance anatomy does no damage to what I had earlier called the "one-sex model." There are three reasons for this: a considerable amount of such evidence had long been available; stray observations do not discredit worldviews; and new supporting evidence for the one-sex model was also available. Moreover, illustrations in the purportedly paradigm-altering texts in fact support the old model. Since there was no radical change during the sixteenth and seventeenth centuries, the reasons offered by Stolberg for why it happened then are moot. The view that biology grounded two sexes (the two-sex model) replaced the view that it reflected imperfectly an underlying metaphysical truth (the one-sex model) as part of the epistemological revolution of the Enlightenment. PMID:12879559

  12. A near infrared laser frequency comb for high precision Doppler planet surveys

    NASA Astrophysics Data System (ADS)

    Osterman, S.; Diddams, S.; Quinlan, F.; Bally, J.; Ge, J.; Ycas, G.

    2011-07-01

    Perhaps the most exciting area of astronomical research today is the study of exoplanets and exoplanetary systems, engaging the imagination not just of the astronomical community, but of the general population. Astronomical instrumentation has matured to the level where it is possible to detect terrestrial planets orbiting distant stars via radial velocity (RV) measurements, with the most stable visible light spectrographs reporting RV results the order of 1 m/s. This, however, is an order of magnitude away from the precision needed to detect an Earth analog orbiting a star such as our sun, the Holy Grail of these efforts. By performing these observations in near infrared (NIR) there is the potential to simplify the search for distant terrestrial planets by studying cooler, less massive, much more numerous class M stars, with a tighter habitable zone and correspondingly larger RV signal. This NIR advantage is undone by the lack of a suitable high precision, high stability wavelength standard, limiting NIR RV measurements to tens or hundreds of m/s [1, 2]. With the improved spectroscopic precision provided by a laser frequency comb based wavelength reference producing a set of bright, densely and uniformly spaced lines, it will be possible to achieve up to two orders of magnitude improvement in RV precision, limited only by the precision and sensitivity of existing spectrographs, enabling the observation of Earth analogs through RV measurements. We discuss the laser frequency comb as an astronomical wavelength reference, and describe progress towards a near infrared laser frequency comb at the National Institute of Standards and Technology and at the University of Colorado where we are operating a laser frequency comb suitable for use with a high resolution H band astronomical spectrograph.

  13. An etalon stabilized 10-GHz comb source using a slab coupled waveguide amplifier

    NASA Astrophysics Data System (ADS)

    Davila-Rodriguez, Josue; Ozdur, Ibrahim T.; Mandridis, Dimitrios; Williams, Charles; Delfyett, Peter J.; Plant, Jason J.; Juodawlkis, Paul W.

    2011-06-01

    An optical comb source based on a slab-coupled optical waveguide amplifier (SCOWA) is presented. The laser is harmonically mode-locked at 10.287 GHz repetition rate and stabilized to an intra-cavity Fabry-Pérot etalon via Pound- Drever-Hall locking. The Fabry-Pérot etalon serves as a reference for the optical frequency of the comb-lines and suppresses the fiber cavity modes to allow only a single longitudinal mode-set to oscillate, generating a frequency comb spaced by the repetition rate. The pulse-to-pulse timing jitter and energy fluctuations are < 2 fs and < 0.03%, respectively (integrated from 1Hz to 100 MHz). Fundamental to this result is the incorporation of the SCOW amplifier as the gain medium and the use of an ultra-low noise sapphire-loaded cavity oscillator to mode-lock the laser. The SCOWA has higher saturation power than commercially available gain media, permitting higher intra-cavity power as well as available power at the output, increasing the power of the photodetected RF tones which increases their signal-to-noise ratio. A high visibility optical frequency comb is observed spanning ~3 nm (at -10 dB), with optical SNR > 60 dB for a cavity with no dispersion compensation. Initial results of a dispersion compensated cavity are presented. A spectral width of ~7.6 nm (-10 dB) was obtained for this case and the pulses can be compressed to near the transform limit at ~930 fs.

  14. Carrier-envelope offset frequency noise analysis in Ti:sapphire frequency combs

    NASA Astrophysics Data System (ADS)

    Sutyrin, Denis V.; Poli, Nicola; Beverini, Nicolò; Tino, Guglielmo M.

    2014-12-01

    We experimentally study two Ti:sapphire optical frequency comb femtosecond regimes, respectively, with a linear and a nonlinear dependence of the carrier-envelope offset frequency (fCEO) on pump intensity. For both regimes, we study the effect of single- and multimode pump lasers on the fCEO phase noise. We demonstrate that the femtosecond regime is playing a more important role on the fCEO phase noise and stability than the pump laser type.

  15. DNA strand exchange stimulated by spontaneous complex formation with cationic comb-type copolymer.

    PubMed

    Kim, Won Jong; Akaike, Toshihiro; Maruyama, Atsushi

    2002-10-30

    Cationic comb-type copolymers (CCCs) composed of a polycation backbone and water-soluble side chains accelerate by 4-5 orders the DNA strand exchange reaction (SER) between double helical DNA and its homologous single-strand DNA. The accelerating effect is considered due to alleviation of counterion association during transitional intermediate formation in sequential displacement pathway. CCCs stabilize not only matured hybrids but also the nucleation complex to accelerate hybridization. PMID:12392411

  16. Aliiroseovarius pelagivivens gen. nov., sp. nov., isolated from seawater, and reclassification of three species of the genus Roseovarius as Aliiroseovarius crassostreae comb. nov., Aliiroseovarius halocynthiae comb. nov. and Aliiroseovarius sediminilitoris comb. nov.

    PubMed

    Park, Sooyeon; Park, Ji-Min; Kang, Chul-Hyung; Yoon, Jung-Hoon

    2015-08-01

    A Gram-stain-negative, non-motile, aerobic and ovoid or rod-shaped bacterium, designated GYSW-22T, was isolated from seawater off Geoje Island in the South Sea, South Korea. Strain GYSW-22T grew optimally at 25 °C, at pH 7.0-8.0 and in the presence of 1.0-2.0% (w/v) NaCl. Neighbour-joining, maximum-likelihood and maximum-parsimony phylogenetic trees based on 16S rRNA gene sequences showed that strain GYSW-22T and the type strains of Roseovarius crassostreae, Roseovarius halocynthiae and Roseovarius sediminilitoris form a coherent cluster, independent of phylogenetic lineages or clusters comprising the type strains of other species of the genus Roseovarius. Strain GYSW-22T exhibited 16S rRNA gene sequence similarities of 97.2, 96.6 and 96.3% to R. halocynthiae MA1-10T, R. crassostreae CV919-312T and R. sediminilitoris M-M10T, respectively, and of 92.6-94.7% to the type strains of other species of the genus Roseovarius. Strain GYSW-22T contained Q-10 as the predominant ubiquinone and C18 : 1ω7c as the major fatty acid. The major polar lipids were phosphatidylcholine, phosphatidylglycerol, one unidentified aminolipid and one unidentified lipid. The DNA G+C content of strain GYSW-22T was 59.0 mol% and its mean DNA-DNA relatedness value with R. halocynthiae MA1-10T was 15 %. On the basis of the data presented, we propose strain GYSW-22T represents a novel species of a new genus, Aliiroseovarius pelagivivens gen. nov., sp. nov. The type strain of the type species is GYSW-22T ( = KCTC 42459T = CECT 8811T). In this study, it is also proposed that Roseovarius crassostreae, Roseovarius halocynthiae and Roseovarius sediminilitoris be reclassified into the new genus as Aliiroseovarius crassostreae comb. nov. (type strain CV919-312T = ATCC BAA-1102T = DSM 16950T), Aliiroseovarius halocynthiae comb. nov. (type strain MA1-10T = KCTC 23462T = CCUG 60745T) and Aliiroseovarius sediminilitoris comb. nov. (type strain M-M10T = KCTC 23959T

  17. Reclassification of Methanogenium tationis and Methanogenium liminatans as Methanofollis tationis gen. nov., comb. nov. and Methanofollis liminatans comb. nov. and description of a new strain of Methanofollis liminatans

    NASA Technical Reports Server (NTRS)

    Zellner, G.; Boone, D. R.; Keswani, J.; Whitman, W. B.; Woese, C. R.; Hagelstein, A.; Tindall, B. J.; Stackebrandt, E.

    1999-01-01

    Sequencing of 16S rRNA genes and phylogenetic analysis of Methanogenium tationis DSM 2702T (OCM 43T) (T = type strain) and Methanogenium liminatans GKZPZT (= DSM 4140T) as well as other members of the family Methanomicrobiaceae revealed that both species belong to a separate line of descent within this family. In addition, a new strain of Methanogenium liminatans, strain BM1 (= DSM 10196), was isolated from a butyrate-degrading, fluidized bed reactor and characterized. Cells of both species are mesophilic, highly irregular cocci that use H2/CO2 and formate for growth and methanogenesis. In addition, Methanogenium liminatans strains GKZPZT and BM1 used 2-propanol/CO2, 2-butanol/CO2 and cyclopentanol/CO2. Both species contained diether and tetraether lipids. The polar lipids comprised amino-phosphopentanetetrol derivatives, which appear to be characteristic lipids within the family Methanomicrobiaceae. The pattern of glycolipids, phosphoglycolipids and amino-phosphoglycolipids was consistent with the assignment of these two species to a taxon within the family Methanomicrobiaceae, but also permitted them to be distinguished from other higher taxa within this family. The G+C contents of the DNA of Methanogenium tationis and Methanogenium liminatans were 54 and 60 mol% (Tm and HPLC), respectively. On the basis of the data presented, the transfer of Methanogenium tationis and Methanogenium liminatans to the genus Methanofollis gen. nov. as Methanofollis tationis comb. nov. and Methanofollis liminatans comb. nov., respectively, is proposed, with Methanofollis tationis as the type species.

  18. Stellar radial velocities using a laser frequency comb: Application and observations in the near infrared

    NASA Astrophysics Data System (ADS)

    Osterman, Steve

    2011-04-01

    The laser frequency comb presents the potential for a revolutionary increase in radial velocity precision by providing a calibration reference of unprecedented quality in terms of wavelength knowledge, repeatability, number, density, and regularity of lines. However, implementation has proven challenging, particularly in the near infrared. Nevertheless, with the right combination of comb and instrument, promising first steps have been taken, allowing for the derivation of stellar radial velocities in a wavelength range which is well suited to the observation of M dwarfs. These stars, with low mass and low luminosity, are the most prevalent class of stars within 10 parsecs and can be expected to yield a higher reflex velocity for a terrestrial mass planet in the liquid water habitable zone than would be the case with a more massive star such as our own. We present the design and both laboratory and on-sky performance of an H-band laser frequency comb used in conjunction with the Penn State Pathfinder testbed spectrograph and discuss lessons learned and plans for follow on testing with both the Pathfinder and the CSHELL instruments.

  19. Frequency-comb formation in doubly resonant second-harmonic generation

    NASA Astrophysics Data System (ADS)

    Leo, F.; Hansson, T.; Ricciardi, I.; De Rosa, M.; Coen, S.; Wabnitz, S.; Erkintalo, M.

    2016-04-01

    We theoretically study the generation of optical frequency combs and corresponding pulse trains in doubly resonant intracavity second-harmonic generation (SHG). We find that, despite the large temporal walk-off characteristic of realistic cavity systems, the nonlinear dynamics can be accurately and efficiently modeled using a pair of coupled mean-field equations. Through rigorous stability analysis of the system's steady-state continuous-wave solutions, we demonstrate that walk-off can give rise to an unexplored regime of temporal modulation instability. Numerical simulations performed in this regime reveal rich dynamical behaviors, including the emergence of temporal patterns that correspond to coherent optical frequency combs. We also demonstrate that the two coupled equations that govern the doubly resonant cavity behavior can, under typical conditions, be reduced to a single mean-field equation akin to that describing the dynamics of singly-resonant-cavity SHG [F. Leo et al., Phys. Rev. Lett. 116, 033901 (2016), 10.1103/PhysRevLett.116.033901]. This reduced approach allows us to derive a simple expression for the modulation instability gain, thus permitting us to acquire significant insight into the underlying physics. We anticipate that our work will have a wide impact on the study of frequency combs in emerging doubly resonant cavity SHG platforms, including quadratically nonlinear microresonators.

  20. A comb-sampling method for enhanced mass analysis in linear electrostatic ion traps

    SciTech Connect

    Greenwood, J. B.; Kelly, O.; Calvert, C. R.; Duffy, M. J.; King, R. B.; Belshaw, L.; Graham, L.; Alexander, J. D.; Williams, I. D.; Bryan, W. A.; Turcu, I. C. E.; Cacho, C. M.; Springate, E.

    2011-04-15

    In this paper an algorithm for extracting spectral information from signals containing a series of narrow periodic impulses is presented. Such signals can typically be acquired by pickup detectors from the image-charge of ion bunches oscillating in a linear electrostatic ion trap, where frequency analysis provides a scheme for high-resolution mass spectrometry. To provide an improved technique for such frequency analysis, we introduce the CHIMERA algorithm (Comb-sampling for High-resolution IMpulse-train frequency ExtRAaction). This algorithm utilizes a comb function to generate frequency coefficients, rather than using sinusoids via a Fourier transform, since the comb provides a superior match to the data. This new technique is developed theoretically, applied to synthetic data, and then used to perform high resolution mass spectrometry on real data from an ion trap. If the ions are generated at a localized point in time and space, and the data is simultaneously acquired with multiple pickup rings, the method is shown to be a significant improvement on Fourier analysis. The mass spectra generated typically have an order of magnitude higher resolution compared with that obtained from fundamental Fourier frequencies, and are absent of large contributions from harmonic frequency components.

  1. Optical Comb Generation for Streak Camera Calibration for Inertial Confinement Fusion Experiments

    SciTech Connect

    Ronald Justin, Terence Davies, Frans Janson, Bruce Marshall, Perry Bell, Daniel Kalantar, Joseph Kimbrough, Stephen Vernon, Oliver Sweningsen

    2008-09-18

    The National Ignition Facility (NIF) at Lawrence Livermore National Laboratory (LLNL) is coming on-line to support physics experimentation for the U.S. Department of Energy (DOE) programs in Inertial Confinement Fusion (ICF) and Stockpile Stewardship (SS). Optical streak cameras are an integral part of the experimental diagnostics instrumentation at NIF. To accurately reduce streak camera data a highly accurate temporal calibration is required. This article describes a technique for simultaneously generating a precise +/- 2 ps optical marker pulse (fiducial reference) and trains of precisely timed, short-duration optical pulses (so-called “comb” pulse trains) that are suitable for the timing calibrations. These optical pulse generators are used with the LLNL optical streak cameras. They are small, portable light sources that, in the comb mode, produce a series of temporally short, uniformly spaced optical pulses, using a laser diode source. Comb generators have been produced with pulse-train repetition rates up to 10 GHz at 780 nm, and somewhat lower frequencies at 664 nm. Individual pulses can be as short as 25-ps FWHM. Signal output is via a fiber-optic connector on the front panel of the generator box. The optical signal is transported from comb generator to streak camera through multi-mode, graded-index optical fiber.

  2. Comb-based radio frequency photonic filtering: Principles, applications and opportunities

    NASA Astrophysics Data System (ADS)

    Wu, Rui

    Photonic technologies have received tremendous attention for enhancement of radio-frequency (RF) systems, including control of phased arrays, analog-to-digital conversion, high-frequency analog signal transmission, and RF signal processing. Among the various applications, implementation of tunable electrical filters over broad RF bandwidths has been much discussed. However, realization of programmable filters with highly selective filter lineshapes, fast RF bandwidth reconfiguration and rapid passband frequency tunability has faced significant challenges. Phase modulated continuous-wave laser frequency combs have seen wide use in various applications such as wavelength division multiplexing networks, optical arbitrary waveform generation, and agile arbitrary millimeter wave generation. Using an optical frequency comb as a multiple carrier optical source offers new potential for achieving complex and tunable RF photonic filters. In this dissertation, I discuss about the generation and application of high-repetition-rate (10 GHz) electro-optic modulated optical frequency combs for our breakthroughs in implementing programmable RF photonic filters with highly selective filter lineshapes (>60 dB mainlobe-to-sidelobe suppression ratio), fast RF bandwidth reconfiguration (˜20 ns reconfiguration speed) and rapid RF passband frequency tunability (˜40 ns tuning speed).

  3. A wavelength-tunable fiber laser based on a twin-core fiber comb filter

    NASA Astrophysics Data System (ADS)

    Zou, Hui; Lou, Shuqin; Yin, Guolu

    2013-02-01

    A wavelength-tunable fiber laser based on a twin-core fiber (TCF) comb filter is proposed and demonstrated. The TCF comb filter is fabricated by splicing a 0.85 m long TCF between two standard single mode fibers (SMFs) and with exhibits a good linear strain characteristic with a sensitivity of 1.23 pm/μɛ. The wavelength of the laser can be linearly tuned from 1558.04 nm to 1553.62 nm by applying an axial strain to the TCF comb filter. The optical signal-to-noise ratio (OSNR) of the fiber laser reaches 45 dB. The 3 dB bandwidth is 0.02 nm. The fluctuation of the laser peak in the output power and the wavelength is less than 0.5 dB and within 0.05 nm, respectively. The fiber laser has the advantages of having a simple structure and stable operation under room temperature.

  4. From a discrete to a continuous model for interpulse interference with a frequency-comb laser

    SciTech Connect

    Zeitouny, M. G.; Cui, M.; Bhattacharya, N.; Urbach, H. P.; Berg, S. A. van den; Janssen, A. J. E. M.

    2010-08-15

    We have investigated correlation patterns generated by a frequency-comb laser in a dispersive unbalanced Michelson interferometer and apply the developed formalism to the case of distance metrology. Due to group velocity dispersion, the position of the brightest fringe of the correlation pattern, which is used for distance determination, cannot be derived by simply using the definition of group refractive index of the dispersive medium. It is shown that the discrete spectrum of the optical frequency comb gives rise to correlation functions which can be represented by a series, namely a discrete correlation series. We have developed a general formalism, valid for any pulse train, extending the discrete model to a continuous model of cross-correlation functions using the Poisson summation. Our model is relevant for any offset and repetition frequency of the frequency comb. From the continuous cross-correlation model we show that, even for a homogeneous dispersive medium the position of the brightest fringe varies nonlinearly for small delay distances and stabilizes for longer ones. We have compared the theoretical results to measurements of pulse propagation in air for path-lengths up to 200 m.

  5. Structure-Specific Liquid Crystal Anchoring Induced by the Molecular Combing of Short Oligonucleotides.

    PubMed

    Chakraborty, Saonti; Noonan, Patrick S; Monserud, Jon; Schwartz, Daniel K

    2015-12-01

    Surface-immobilized oligonucleotides were "combed" by meniscus motion and exposed to a nematic liquid crystal (LC). Although the oligonucleotides were as short as 16 bases, they were apparently oriented by this process and, in turn, successfully biased the orientation of the adjacent LC material. Single-stranded DNA (ssDNA) induced LC orientation in the combing direction, while hybridized double-stranded DNA (dsDNA) rotated the azimuthal LC orientation by ∼30° from the combing direction. The sensitivity of the chiral response to mixed ssDNA/dsDNA surfaces was characterized by employing complementary DNA that was longer than the immobilized DNA, resulting in single-stranded overhangs of various lengths. A rotated LC orientation was observed even when more than 70% of the DNA was single-stranded, and the transition from the rotated to nonrotated response was apparently discontinuous as a function of ssDNA surface coverage. These phenomena represent a sensitive DNA hybridization detection strategy that can potentially comprise a multiplexed assay. PMID:26562585

  6. Optical frequency comb generation based on chirping of Mach-Zehnder Modulators

    NASA Astrophysics Data System (ADS)

    Hmood, Jassim K.; Emami, Siamak D.; Noordin, Kamarul A.; Ahmad, Harith; Harun, Sulaiman W.; Shalaby, Hossam M. H.

    2015-06-01

    A new approach for the generation of an optical frequency comb, based on chirping of modulators, is proposed and numerically demonstrated. The setup includes two cascaded Mach-Zehnder Modulators (MZMs), a sinusoidal wave oscillator, and an electrical time delay. The first MZM is driven directly by a sinusoidal wave, while the second MZM is driven by a delayed replica of the sinusoidal wave. A mathematical model of the proposed system is formulated and modeled using the Matlab software. It is shown that the number of the frequency lines is directly proportional to the chirp factor. In order to achieve the highest number of frequency comb lines with the best flatness, the time delay between the driving voltages of the two MZMs is optimized. Our results reveal that at least 51 frequency lines can be observed at the output spectrum. In addition, 27 of these lines have power fluctuations of less than 1 dB. The performance of the proposed system is also simulated using a split-step numerical analysis. An optical frequency comb, with tunable frequency spacing ranging from 5 to 40 GHz, is successfully generated.

  7. A mummified duck-billed dinosaur with a soft-tissue cock's comb.

    PubMed

    Bell, Phil R; Fanti, Federico; Currie, Philip J; Arbour, Victoria M

    2014-01-01

    Among living vertebrates, soft tissues are responsible for labile appendages (combs, wattles, proboscides) that are critical for activities ranging from locomotion to sexual display [1]. However, soft tissues rarely fossilize, and such soft-tissue appendages are unknown for many extinct taxa, including dinosaurs. Here we report a remarkable "mummified" specimen of the hadrosaurid dinosaur Edmontosaurus regalis from the latest Cretaceous Wapiti Formation, Alberta, Canada, that preserves a three-dimensional cranial crest (or "comb") composed entirely of soft tissue. Previously, crest function has centered on the hypertrophied nasal passages of lambeosaurine hadrosaurids, which acted as resonance chambers during vocalization [2-4]. The fleshy comb in Edmontosaurus necessitates an alternative explanation most likely related to either social signaling or sexual selection [5-7]. This discovery provides the first view of bizarre, soft-tissue signaling structures in a dinosaur and provides additional evidence for social behavior. Crest evolution within Hadrosaurinae apparently culminated in the secondary loss of the bony crest at the terminal Cretaceous; however, the new specimen indicates that cranial ornamentation was in fact not lost but substituted in Edmontosaurus by a fleshy display structure. It also implies that visual display played a key role in the evolution of hadrosaurine crests and raises the possibility of similar soft-tissue structures among other dinosaurs. PMID:24332547

  8. Spectral distortion of dual-comb spectrometry due to repetition rate fluctuation

    NASA Astrophysics Data System (ADS)

    Hong-Lei, Yang; Hao-Yun, Wei; Yan, Li

    2016-04-01

    Dual-comb spectrometry suffers the fluctuations of parameters in combs. We demonstrate that the repetition rate is more important than any other parameter, since the fluctuation of the repetition rate leads to a change of difference in the repetition rate between both combs, consequently causing the conversion factor variation and spectral frequency misalignment. The measured frequency noise power spectral density of the repetition rate exhibits an integrated residual frequency modulation of 1.4 Hz from 1 Hz to 100 kHz in our system. This value corresponds to the absorption peak fluctuation within a root mean square value of 0.19 cm‑1 that is verified by both simulation and experimental result. Further, we can also simulate spectrum degradation as the fluctuation varies. After modifying misaligned spectra and averaging, the measured result agrees well with the simulated spectrum based on the GEISA database. Project supported by the State Key Laboratory of Precision Measurement Technology & Instruments of Tsinghua University and the Young Scientists Fund of the National Natural Science Foundation of China (Grant No. 61205147).

  9. Radius of Gyration of Polystyrene Combs and Centipedes in a O Solvent

    SciTech Connect

    Terao, Ken; Farmer, Brandon S; Nakamura, Yo; Iatrou, Hermis; Hong, Kunlun; Mays, Jimmy

    2005-01-01

    The molecular weight dependence of the radii of gyration R{sub g} in a {var_theta} solvent (trans-decalin) of one regular branched comb and three regular centipede polystyrenes was studied using a gel permeation chromatography system equipped with a two-angle light scattering detector and a refractive index detector. R{sub g} in trans-decalin for each sample of particular molecular weight was about 25% smaller than that in a good solvent (tetrahydrofuran, THF). On the other hand, they are 20--40% larger than the theoretical values from the Gaussian chain model. This difference can be explained with the wormlike comb model developed by Nakamura et al. (Macromolecules 2000, 33, 8323-8328). Persistence lengths thus obtained for each sample were about half of that determined in THF solution. However, they are significantly larger than that for linear polystyrene. These results suggest that a main chain stiffening effect exists in comb polystyrenes even in a {var_theta} solvent.

  10. Gigahertz frequency comb offset stabilization based on supercontinuum generation in silicon nitride waveguides.

    PubMed

    Klenner, Alexander; Mayer, Aline S; Johnson, Adrea R; Luke, Kevin; Lamont, Michael R E; Okawachi, Yoshitomo; Lipson, Michal; Gaeta, Alexander L; Keller, Ursula

    2016-05-16

    Silicon nitride (Si3N4) waveguides represent a novel photonic platform that is ideally suited for energy efficient and ultrabroadband nonlinear interactions from the visible to the mid-infrared. Chip-based supercontinuum generation in Si3N4 offers a path towards a fully-integrated and highly compact comb source for sensing and time-and-frequency metrology applications. We demonstrate the first successful frequency comb offset stabilization that utilizes a Si3N4 waveguide for octave-spanning supercontinuum generation and achieve the lowest integrated residual phase noise of any diode-pumped gigahertz laser comb to date. In addition, we perform a direct comparison to a standard silica photonic crystal fiber (PCF) using the same ultrafast solid-state laser oscillator operating at 1 µm. We identify the minimal role of Raman scattering in Si3N4 as a key benefit that allows to overcome the fundamental limitations of silica fibers set by Raman-induced self-frequency shift. PMID:27409927

  11. A Y+J Band Laser Frequency Comb for the Habitable Zone Planet Finder

    NASA Astrophysics Data System (ADS)

    Osterman, Steve; Ycas, G. G.; Diddams, S. A.; Bender, C. F.; Donaldson, C. L.; Mahadevan, S.; Quinlan, F.; Ramsey, L. W.

    2013-01-01

    The Habitable Zone Planet Finder (HPF) scheduled for deployment to the Hobby-Eberly Telescope in late 2015 will extend the radial velocity search for exoplanets into the near infrared by providing a high precision, stabilized near infrared spectrograph spanning the Y+J bands (0.98-1.3μm) with 50,000 resolution. Working in the near infrared will allow the HPF to study cooler, lower mass stars than is possible with the current generation of optical spectrographs. In order to extend the precision of the HPF to lower minimum RV signatures we are proposing to develop a deployable, fully autonomous version of the Y+J band laser frequency comb currently in operation at the NIST Time and Frequency Division in Boulder, Colorado. The Y+J comb is derived from the H band (1.45-1.7μm) comb which was successfully demonstrated at the Hobby-Eberly Telescope in 2010. The deployed version will leverage off of existing hardware and demonstrated technology. We present instrument architecture and current performance as well as results of long term stability tests, filter modeling, modal noise reduction results and predicted end-to-end performance.

  12. A comb filter based signal processing method to effectively reduce motion artifacts from photoplethysmographic signals.

    PubMed

    Peng, Fulai; Liu, Hongyun; Wang, Weidong

    2015-10-01

    A photoplethysmographic (PPG) signal can provide very useful information about a subject's cardiovascular status. Motion artifacts (MAs), which usually deteriorate the waveform of a PPG signal, severely obstruct its applications in the clinical diagnosis and healthcare area. To reduce the MAs from a PPG signal, in the present study we present a comb filter based signal processing method. Firstly, wavelet de-noising was implemented to preliminarily suppress a part of the MAs. Then, the PPG signal in the time domain was transformed into the frequency domain by a fast Fourier transform (FFT). Thirdly, the PPG signal period was estimated from the frequency domain by tracking the fundamental frequency peak of the PPG signal. Lastly, the MAs were removed by the comb filter which was designed based on the obtained PPG signal period. Experiments with synthetic and real-world datasets were implemented to validate the performance of the method. Results show that the proposed method can effectively restore the PPG signals from the MA corrupted signals. Also, the accuracy of blood oxygen saturation (SpO2), calculated from red and infrared PPG signals, was significantly improved after the MA reduction by the proposed method. Our study demonstrates that the comb filter can effectively reduce the MAs from a PPG signal provided that the PPG signal period is obtained. PMID:26334000

  13. Sex and Fertility After SCI

    MedlinePlus

    Experts \\ Sex and Fertility After Spinal Cord Injury Topics Adult Injuries Spinal Cord Injury 101 Spinal Cord Injury 101 ... Spasticity, Physical Therapy-Lokomat Spasticity, Physical Therapy-Lokomat Sex and Fertility After Spinal Cord Injury Sex and ...

  14. Hepatitis C: Sex and Sexuality

    MedlinePlus

    ... with Hepatitis » Sex and Sexuality: Entire Lesson Viral Hepatitis Menu Menu Viral Hepatitis Viral Hepatitis Home For ... hepatitis C virus through sex. Can you pass hepatitis C to a sex partner? Yes, but it ...

  15. Demonstration of a near-IR line-referenced electro-optical laser frequency comb for precision radial velocity measurements in astronomy.

    PubMed

    Yi, X; Vahala, K; Li, J; Diddams, S; Ycas, G; Plavchan, P; Leifer, S; Sandhu, J; Vasisht, G; Chen, P; Gao, P; Gagne, J; Furlan, E; Bottom, M; Martin, E C; Fitzgerald, M P; Doppmann, G; Beichman, C

    2016-01-01

    An important technique for discovering and characterizing planets beyond our solar system relies upon measurement of weak Doppler shifts in the spectra of host stars induced by the influence of orbiting planets. A recent advance has been the introduction of optical frequency combs as frequency references. Frequency combs produce a series of equally spaced reference frequencies and they offer extreme accuracy and spectral grasp that can potentially revolutionize exoplanet detection. Here we demonstrate a laser frequency comb using an alternate comb generation method based on electro-optical modulation, with the comb centre wavelength stabilized to a molecular or atomic reference. In contrast to mode-locked combs, the line spacing is readily resolvable using typical astronomical grating spectrographs. Built using commercial off-the-shelf components, the instrument is relatively simple and reliable. Proof of concept experiments operated at near-infrared wavelengths were carried out at the NASA Infrared Telescope Facility and the Keck-II telescope. PMID:26813804

  16. Coherence properties of a 2.6-7.5  μm frequency comb produced as a subharmonic of a Tm-fiber laser.

    PubMed

    Smolski, V O; Yang, H; Gorelov, S D; Schunemann, P G; Vodopyanov, K L

    2016-04-01

    We study the temporal coherence of an ultrabroadband frequency comb produced in a degenerate GaAs optical parametric oscillator (OPO) pumped by a stabilized Tm-fiber comb, by observing multiheterodyne beats in the RF domain. We infer that in such a regime the OPO automatically produces a stable frequency comb that is phase and frequency locked to the pump. By varying intracavity dispersion, we achieve a comb spanning 2.6-7.5 μm at a -20  dB level. Low pump threshold (down to 7 mW), high average power (up to 73 mW), broad spectral coverage, flat spectrum, and high coherence make this comb a source suitable for various applications, foremost dual-comb molecular spectroscopy. PMID:27192243

  17. Demonstration of a near-IR line-referenced electro-optical laser frequency comb for precision radial velocity measurements in astronomy

    NASA Astrophysics Data System (ADS)

    Yi, X.; Vahala, K.; Li, J.; Diddams, S.; Ycas, G.; Plavchan, P.; Leifer, S.; Sandhu, J.; Vasisht, G.; Chen, P.; Gao, P.; Gagne, J.; Furlan, E.; Bottom, M.; Martin, E. C.; Fitzgerald, M. P.; Doppmann, G.; Beichman, C.

    2016-01-01

    An important technique for discovering and characterizing planets beyond our solar system relies upon measurement of weak Doppler shifts in the spectra of host stars induced by the influence of orbiting planets. A recent advance has been the introduction of optical frequency combs as frequency references. Frequency combs produce a series of equally spaced reference frequencies and they offer extreme accuracy and spectral grasp that can potentially revolutionize exoplanet detection. Here we demonstrate a laser frequency comb using an alternate comb generation method based on electro-optical modulation, with the comb centre wavelength stabilized to a molecular or atomic reference. In contrast to mode-locked combs, the line spacing is readily resolvable using typical astronomical grating spectrographs. Built using commercial off-the-shelf components, the instrument is relatively simple and reliable. Proof of concept experiments operated at near-infrared wavelengths were carried out at the NASA Infrared Telescope Facility and the Keck-II telescope.

  18. Demonstration of a near-IR line-referenced electro-optical laser frequency comb for precision radial velocity measurements in astronomy

    PubMed Central

    Yi, X.; Vahala, K.; Li, J.; Diddams, S.; Ycas, G.; Plavchan, P.; Leifer, S.; Sandhu, J.; Vasisht, G.; Chen, P.; Gao, P.; Gagne, J.; Furlan, E.; Bottom, M.; Martin, E. C.; Fitzgerald, M. P.; Doppmann, G.; Beichman, C.

    2016-01-01

    An important technique for discovering and characterizing planets beyond our solar system relies upon measurement of weak Doppler shifts in the spectra of host stars induced by the influence of orbiting planets. A recent advance has been the introduction of optical frequency combs as frequency references. Frequency combs produce a series of equally spaced reference frequencies and they offer extreme accuracy and spectral grasp that can potentially revolutionize exoplanet detection. Here we demonstrate a laser frequency comb using an alternate comb generation method based on electro-optical modulation, with the comb centre wavelength stabilized to a molecular or atomic reference. In contrast to mode-locked combs, the line spacing is readily resolvable using typical astronomical grating spectrographs. Built using commercial off-the-shelf components, the instrument is relatively simple and reliable. Proof of concept experiments operated at near-infrared wavelengths were carried out at the NASA Infrared Telescope Facility and the Keck-II telescope. PMID:26813804

  19. Sex/Gender Medicine

    PubMed Central

    Arain, Faisal A.; Kuniyoshi, Fatima H.; Abdalrhim, Ahmed D.; Miller, Virginia M.

    2010-01-01

    Sex differences in morbidity and mortality associated with cardiovascular disease have been recognized by the medical com006Dunity for decades. Investigation into the underlying biological basis of these differences was largely neglected by the scientific community until a report released by the Institute of Medicine in the United States in 2001 “Exploring the Biological Contributions to Human Health: Does Sex Matter?” Recommendations from this report included the need for more accurate use of the terms “sex” and “gender”, better tools and resources to study the biological basis of sex differences, integration of findings from different levels of biological organization and continued synergy between basic and clinical researchers. Ten years after the Institute’s report, this review evaluates some of the sex differences in cardiovascular disease, reviews new approaches to study sex differences and emphasizes areas where further research is required. In the era of personalized medicine, the study of the biological basis of sex differences promises to optimize preventive, diagnostic and therapeutic strategies for cardiovascular disease in men and women, but will require diligence by the scientific and medical communities to remember that sex does matter. PMID:19729858

  20. Effect of partial comb and wattle trim on pullet behavior and thermoregulation,1.

    PubMed

    Hester, P Y; Al-Ramamneh, D S; Makagon, M M; Cheng, H W

    2015-05-01

    The wattles and comb of chickens are important for thermoregulation allowing for heat exchange during high temperatures. These integumentary tissues are sometimes trimmed to prevent tears if caught on cage equipment and to also improve feed efficiency; however, the procedure itself could be painful to chicks. Our objective was to determine the effect of trimming the comb and wattles on behavior, BW, feed usage, and the surface temperature of pullets. The wattles and comb of Leghorns were partially trimmed at 21 d age (n = 6 cages, 13 chicks each) with another 6 cages serving as controls. Behaviors were recorded 3 times daily for 1 h starting at 0800, 1200, and 1500 using instantaneous scan sampling observations conducted every 5 min prior to, on the d of, and after the trim. Group BW at 21, 28, and 36 d age and the amount of feed used for 7 d beginning at 21 and 29 d age were measured per cage. At 1300 h on d before and after the trim, thermal images of the pullet's beak, comb, eye, wattle, and shank were randomly taken on 3 pullets/cage. Smaller proportions of trimmed chicks were eating and greater proportions were sitting on the d of the trim as compared to the controls with the opposite trend occurring on 4 d post-trim (treatment by age interaction, P = 0.03 and 0.0001, respectively). Standing behavior differed only on the d of the trim where smaller proportions of trimmed pullets stood as compared to intact controls (treatment by age interaction, P = 0.0002). Trimming the comb and wattles did not affect preening, running, BW, feed utilization, and the surface temperature of the pullet. The indices of behavior suggest that on the d of the trim, pullets may have experienced temporary distress, but they returned to normal behavior by 5 h post-trim with no long-term effect on BW, feed usage, or surface body temperature. PMID:25796274