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Sample records for sex combs asx

  1. Drosophila Sex Combs as a Model of Evolutionary Innovations

    PubMed Central

    Kopp, Artyom

    2011-01-01

    The diversity of animal and plant forms is shaped by nested evolutionary innovations. Understanding the genetic and molecular changes responsible for these innovations is therefore one of the key goals of evolutionary biology. From the genetic point of view, the origin of novel traits implies the origin of new regulatory pathways to control their development. To understand how these new pathways are assembled in the course of evolution, we need model systems that combine relatively recent innovations with a powerful set of genetic and molecular tools. One such model is provided by the Drosophila sex comb a male-specific morphological structure that evolved in a relatively small lineage related to the model species D. melanogaster. Our extensive knowledge of sex comb development in D. melanogaster provides the basis for investigating the genetic changes responsible for sex comb origin and diversification. At the same time, sex combs can change on microevolutionary timescales and differ spectacularly among closely related species, providing opportunities for direct genetic analysis and for integrating developmental and population-genetic approaches. Sex comb evolution is associated with the origin of novel interactions between HOX and sex determination genes. Activity of the sex determination pathway was brought under the control of the HOX code to become segment-specific, while HOX gene expression became sexually dimorphic. At the same time, both HOX and sex determination genes were integrated into the intrasegmental spatial patterning network, and acquired new joint downstream targets. Phylogenetic analysis shows that similar sex comb morphologies evolved independently in different lineages. Convergent evolution at the phenotypic level reflects convergent changes in the expression of HOX and sex determination genes, involving both independent gains and losses of regulatory interactions. However, the downstream cell differentiation programs have diverged between species, and in some lineages similar adult morphologies are produced by different morphogenetic mechanisms. These features make the sex comb an excellent model for examining not only the genetic changes responsible for its evolution, but also the cellular processes that translate DNA sequence changes into morphological diversity. The origin and diversification of sex combs provides insights into the roles of modularity, cooption, and regulatory changes in evolutionary innovations, and can serve as a model for understanding the origin of the more drastic novelties that define higher-order taxa. PMID:23016935

  2. Wing Defects in Drosophila xenicid Mutant Clones Are Caused by C-Terminal Deletion of Additional Sex Combs (Asx)

    PubMed Central

    Bischoff, Kara; Ballew, Anna C.; Simon, Michael A.; O'Reilly, Alana M.

    2009-01-01

    Background The coordinated action of genes that control patterning, cell fate determination, cell size, and cell adhesion is required for proper wing formation in Drosophila. Defects in any of these basic processes can lead to wing aberrations, including blisters. The xenicid mutation was originally identified in a screen designed to uncover regulators of adhesion between wing surfaces [1]. Principal Findings Here, we demonstrate that expression of the βPS integrin or the patterning protein Engrailed are not affected in developing wing imaginal discs in xenicid mutants. Instead, expression of the homeotic protein Ultrabithorax (Ubx) is strongly increased in xenicid mutant cells. Conclusion Our results suggest that upregulation of Ubx transforms cells from a wing blade fate to a haltere fate, and that the presence of haltere cells within the wing blade is the primary defect leading to the adult wing phenotypes observed. PMID:19956620

  3. Evolution of Drosophila sex comb length illustrates the inextricable interplay between selection and variation

    PubMed Central

    Malagón, Juan N.; Ahuja, Abha; Sivapatham, Gabilan; Hung, Julian; Lee, Jiwon; Muñoz-Gómez, Sergio A.; Atallah, Joel; Singh, Rama S.; Larsen, Ellen

    2014-01-01

    In spite of the diversity of possible biological forms observed in nature, a limited range of morphospace is frequently occupied for a given trait. Several mechanisms have been proposed to explain this bias in the distribution of phenotypes including selection, drift, and developmental constraints. Despite extensive work on phenotypic bias, the underlying developmental mechanisms explaining why particular regions of morphological space remain unoccupied are poorly understood. To address this issue, we studied the sex comb, a group of modified bristles used in courtship that shows marked morphological diversity among Drosophila species. In many Drosophila species including Drosophila melanogaster, the sex comb rotates 90° to a vertical position during development. Here we analyze the effect of changing D. melanogaster sex comb length on the process of rotation. We find that artificial selection changes the number of bristles per comb without a proportional change in the space available for rotation. As a result, when increasing sex comb length, rather than displaying a similar straight vertical shape observed in other Drosophila species, long sex combs bend because rotation is blocked by a neighboring row of bristles. Our results show ways in which morphologies that would be favored by natural selection are apparently impossible to achieve developmentally. These findings highlight the potential role of development in modifying selectable variation in the evolution of Drosophila sex comb length. PMID:25197080

  4. Distinct developmental mechanisms underlie the evolutionary diversification of Drosophila sex combs

    PubMed Central

    Tanaka, Kohtaro; Barmina, Olga; Kopp, Artyom

    2009-01-01

    Similar selective pressures can lead to independent origin of similar morphological structures in multiple evolutionary lineages. Developmental mechanisms underlying convergent evolution remain poorly understood. In this report, we show that similar sex comb morphology in closely related Drosophila species is produced by different cellular mechanisms. The sex comb is a recently evolved, male-specific array of modified bristles derived from transverse bristle rows found on the first thoracic legs in both sexes. “Longitudinal” sex combs oriented along the proximo-distal leg axis evolved independently in several Drosophila lineages. We show that in some of these lineages, sex combs originate as one or several transverse bristle rows that subsequently rotate 90° and align to form a single longitudinal row. In other species, bristle cells that make up the sex combs arise in their final longitudinal orientation. Thus, sex combs can develop through either sex-specific patterning of bristle precursor cells or male-specific morphogenesis of sexually monomorphic precursors. Surprisingly, the two mechanisms produce nearly identical morphology in some species. Phylogenetic analysis shows that each of these mechanisms has probably evolved repeatedly in different Drosophila lineages, suggesting that selection can recruit different cellular processes to produce similar functional solutions. PMID:19255422

  5. Needs and targets for the multi sex combs gene product in Drosophila melanogaster.

    PubMed Central

    Saget, O; Forquignon, F; Santamaria, P; Randsholt, N B

    1998-01-01

    We have analyzed the requirements for the multi sex combs (mxc) gene during development to gain further insight into the mechanisms and developmental processes that depend on the important trans-regulators forming the Polycomb group (PcG) in Drosophila melanogaster. mxc is allelic with the tumor suppressor locus lethal (1) malignant blood neoplasm (l(1)mbn). We show that the mxc product is dramatically needed in most tissues because its loss leads to cell death after a few divisions. mxc has also a strong maternal effect. We find that hypomorphic mxc mutations enhance other PcG gene mutant phenotypes and cause ectopic expression of homeotic genes, confirming that PcG products are cooperatively involved in repression of selector genes outside their normal expression domains. We also demonstrate that the mxc product is needed for imaginal head specification, through regulation of the ANT-C gene Deformed. Our analysis reveals that mxc is involved in the maternal control of early zygotic gap gene expression previously reported for some PcG genes and suggests that the mechanism of this early PcG function could be different from the PcG-mediated regulation of homeotic selector genes later in development. We discuss these data in view of the numerous functions of PcG genes during development. PMID:9691040

  6. Regulation of larval hematopoiesis in Drosophila melanogaster: a role for the multi sex combs gene.

    PubMed Central

    Remillieux-Leschelle, Nathalie; Santamaria, Pedro; Randsholt, Neel B

    2002-01-01

    Drosophila larval hematopoietic organs produce circulating hemocytes that ensure the cellular host defense by recognizing and neutralizing non-self or noxious objects through phagocytosis or encapsulation and melanization. Hematopoietic lineage specification as well as blood cell proliferation and differentiation are tightly controlled. Mutations in genes that regulate lymph gland cell proliferation and hemocyte numbers in the body cavity cause hematopoietic organ overgrowth and hemocyte overproliferation. Occasionally, mutant hemocytes invade self-tissues, behaving like neoplastic malignant cells. Two alleles of the Polycomb group (PcG) gene multi sex combs (mxc) were previously isolated as such lethal malignant blood neoplasm mutations. PcG genes regulate Hox gene expression in vertebrates and invertebrates and participate in mammalian hematopoiesis control. Hence we investigated the need for mxc in Drosophila hematopoietic organs and circulating hemocytes. We show that mxc-induced hematopoietic hyperplasia is cell autonomous and that mxc mainly controls plasmatocyte lineage proliferation and differentiation in lymph glands and circulating hemocytes. Loss of the Toll pathway, which plays a similar role in hematopoiesis, counteracted mxc hemocyte proliferation but not mxc hemocyte differentiation. Several PcG genes tested in trans had no effects on mxc hematopoietic phenotypes, whereas the trithorax group gene brahma is important for normal and mutant hematopoiesis control. We propose that mxc provides one of the regulatory inputs in larval hematopoiesis that control normal rates of plasmatocyte and crystal lineage proliferation as well as normal rates and timing of hemocyte differentiation. PMID:12454071

  7. Evolutionary conservation and predicted structure of the Drosophila extra sex combs repressor protein.

    PubMed Central

    Ng, J; Li, R; Morgan, K; Simon, J

    1997-01-01

    The Drosophila extra sex combs (esc) protein, a member of the Polycomb group (PcG), is a transcriptional repressor of homeotic genes. Genetic studies have shown that esc protein is required in early embryos at about the time that other PcG proteins become engaged in homeotic gene repression. The esc protein consists primarily of multiple copies of the WD repeat, a motif that has been implicated in protein-protein interaction. To further investigate the domain organization of esc protein, we have isolated and characterized esc homologs from divergent insect species. We report that esc protein is highly conserved in housefly (72% identical to Drosophila esc), butterfly (55% identical), and grasshopper (56% identical). We show that the butterfly homolog provides esc function in Drosophila, indicating that the sequence similarities reflect functional conservation. Homology modeling using the crystal structure of another WD repeat protein, the G-protein beta-subunit, predicts that esc protein adopts a beta-propeller structure. The sequence comparisons and modeling suggest that there are seven WD repeats in esc protein which together form a seven-bladed beta-propeller. We locate the conserved regions in esc protein with respect to this predicted structure. Site-directed mutagenesis of specific loops, predicted to extend from the propeller surface, identifies conserved parts of esc protein required for function in vivo. We suggest that these regions might mediate physical interaction with esc partner proteins. PMID:9343430

  8. Characterization of the Cis-Regulatory Region of the Drosophila Homeotic Gene Sex Combs Reduced

    PubMed Central

    Gindhart-Jr., J. G.; King, A. N.; Kaufman, T. C.

    1995-01-01

    The Drosophila homeotic gene Sex combs reduced (Scr) controls the segmental identity of the labial and prothoracic segments in the embryo and adult. It encodes a sequence-specific transcription factor that controls, in concert with other gene products, differentiative pathways of tissues in which Scr is expressed. During embryogenesis, Scr accumulation is observed in a discrete spatiotemporal pattern that includes the labial and prothoracic ectoderm, the subesophageal ganglion of the ventral nerve cord and the visceral mesoderm of the anterior and posterior midgut. Previous analyses have demonstrated that breakpoint mutations located in a 75-kb interval, including the Scr transcription unit and 50 kb of upstream DNA, cause Scr misexpression during development, presumably because these mutations remove Scr cis-regulatory sequences from the proximity of the Scr promoter. To gain a better understanding of the regulatory interactions necessary for the control of Scr transcription during embryogenesis, we have begun a molecular analysis of the Scr regulatory interval. DNA fragments from this 75-kb region were subcloned into P-element vectors containing either an Scr-lacZ or hsp70-lacZ fusion gene, and patterns of reporter gene expression were assayed in transgenic embryos. Several fragments appear to contain Scr regulatory sequences, as they direct reporter gene expression in patterns similar to those normally observed for Scr, whereas other DNA fragments direct Scr reporter gene expression in developmentally interesting but non-Scr-like patterns during embryogenesis. Scr expression in some tissues appears to be controlled by multiple regulatory elements that are separated, in some cases, by more than 20 kb of intervening DNA. Interestingly, regulatory sequences that direct reporter gene expression in an Scr-like pattern in the anterior and posterior midgut are imbedded in the regulatory region of the segmentation gene fushi tarazu (ftz), which is normally located between 10 and 20 kb 5' of the Scr transcription start site. This analysis provides an entry point for the study of how Scr transcription is regulated at the molecular level. PMID:7713432

  9. The Polycomb-group gene, extra sex combs, encodes a nuclear member of the WD-40 repeat family.

    PubMed Central

    Gutjahr, T; Frei, E; Spicer, C; Baumgartner, S; White, R A; Noll, M

    1995-01-01

    We have delimited the extra sex combs (esc) gene to < 4 kb that include a single transcript and are able to rescue both the maternal and zygotic esc phenotypes. Several mutations have been identified within the esc transcript. In agreement with earlier genetic studies, esc is expressed maternally and its product is most abundant during the early embryonic stages. It encodes a protein of the WD-40 repeat family, which localizes predominantly to the nucleus. During germ band extension, it is expressed in a stereotypic pattern of neuroblasts. We propose a model in which Esc is recruited by gap proteins both to act as a corepressor that competes with the TAFII80 coactivator to block transcription and also to mediate the transition to permanent repression by Polycomb-group proteins. Images PMID:7556071

  10. The Homeotic Gene Sex Combs Reduced of Drosophila Melanogaster Is Differentially Regulated in the Embryonic and Imaginal Stages of Development

    PubMed Central

    Pattatucci, A. M.; Kaufman, T. C.

    1991-01-01

    The Sex combs reduced (Scr) locus is unique among the genes contained within the Antennapedia complex (ANT-C) of Drosophila melanogaster in that it directs functions that are required for both cephalic and thoracic development in the embryo and the adult. Antibodies raised against protein encoded by Scr were used to follow the distribution of this gene product in embryos and imaginal discs of third instar larvae. Analysis of Scr protein accumulation in embryos hemizygous for breakpoint lesions mapping throughout the locus has allowed us to determine that sequences required for establishment of the Scr embryonic pattern are contained within a region of DNA that overlaps with the identified upstream regulatory region of the segmentation gene fushi tarazu (ftz). Gain-of-function mutations in Scr result in the presence of ectopic sex comb teeth on the first tarsal segment of mesothoracic and metathoracic legs of adult males. Heterozygous combinations of gain-of-function alleles with a wild-type Scr gene exhibit no evidence of ectopic protein localization in the second and third thoracic segments of embryos. However, mesothoracic and metathoracic leg imaginal discs can be shown to accumulate ectopically expressed Scr protein, implying a differential regulation of the Scr gene during these two periods of development. Additionally, we have found that the spatial pattern of Scr gene expression in imaginal tissues involved in the development of the adult thorax is governed in part by synapsis of homologous chromosomes in this region of the ANT-C. However, those imaginal discs that arise anteriorly to the prothorax do not appear to be sensitive to this form of gene regulation. Finally, we have demonstrated that the extent of Scr expression is influenced by mutations at the Polycomb (Pc) locus but not by mutant alleles of the zeste (z) gene. Taken together, our data suggests that Scr gene expression is differentially regulated both temporally and spatially in a manner that is sensitive to the structure of the locus. PMID:1683847

  11. A Logical OR Redundancy Within the Asx-Pro-Asx-Gly Type I beta-Turn Motif

    SciTech Connect

    Lee,J.; Dubey, V.; Longo, L.; Blaber, M.

    2008-01-01

    Turn secondary structure is essential to the formation of globular protein architecture. Turn structures are, however, much more complex than either ?-helix or ?-sheet, and the thermodynamics and folding kinetics are poorly understood. Type I ?-turns are the most common type of reverse turn, and they exhibit a statistical consensus sequence of Asx-Pro-Asx-Gly (where Asx is Asp or Asn). A comprehensive series of individual and combined Asx mutations has been constructed within three separate type I 3:5 G1 bulge ?-turns in human fibroblast growth factor-1, and their effects on structure, stability, and folding have been determined. The results show a fundamental logical OR relationship between the Asx residues in the motif, involving H-bond interactions with main-chain amides within the turn. These interactions can be modulated by additional interactions with residues adjacent to the turn at positions i + 4 and i + 6. The results show that the Asx residues in the turn motif make a substantial contribution to the overall stability of the protein, and the Asx logical OR relationship defines a redundant system that can compensate for deleterious point mutations. The results also show that the stability of the turn is unlikely to be the prime determinant of formation of turn structure in the folding transition state.

  12. A Logical OR Redundancy within the Asx-Pro-Asx-Gly Type 1 {Beta}-Turn Motif

    SciTech Connect

    Lee, Jihun; Dubey, Vikash Kumar; Longo, Lian M.; Blaber, Michael

    2008-04-19

    Turn secondary structure is essential to the formation of globular protein architecture. Turn structures are, however, much more complex than either {alpha}-helix or {beta}-sheet, and the thermodynamics and folding kinetics are poorly understood. Type I {beta}-turns are the most common type of reverse turn, and they exhibit a statistical consensus sequence of Asx-Pro-Asx-Gly (where Asx is Asp or Asn). A comprehensive series of individual and combined Asx mutations has been constructed within three separate type I 3:5 G1 bulge {beta}-turns in human fibroblast growth factor-1, and their effects on structure, stability, and folding have been determined. The results show a fundamental logical OR relationship between the Asx residues in the motif, involving H-bond interactions with main-chain amides within the turn. These interactions can be modulated by additional interactions with residues adjacent to the turn at positions i + 4 and i + 6. The results show that the Asx residues in the turn motif make a substantial contribution to the overall stability of the protein, and the Asx logical OR relationship defines a redundant system that can compensate for deleterious point mutations. The results also show that the stability of the turn is unlikely to be the prime determinant of formation of turn structure in the folding transition state.

  13. Expression and properties of wild-type and mutant forms of the Drosophila sex comb on midleg (SCM) repressor protein.

    PubMed Central

    Bornemann, D; Miller, E; Simon, J

    1998-01-01

    The Sex comb on midleg (Scm) gene encodes a transcriptional repressor of the Polycomb group (PcG). Here we show that SCM protein is nuclear and that its expression is widespread during fly development. SCM protein contains a C-terminal domain, termed the SPM domain, which mediates protein-protein interactions. The biochemical function of another domain consisting of two 100-amino-acid-long repeats, termed "mbt" repeats, is unknown. We have determined the molecular lesions of nine Scm mutant alleles, which identify functional requirements for specific domains. The Scm alleles were tested for genetic interactions with mutations in other PcG genes. Intriguingly, three hypomorphic Scm mutations, which map within an mbt repeat, interact with PcG mutations more strongly than do Scm null alleles. The strongest interactions produce partial synthetic lethality that affects doubly heterozygous females more severely than males. We show that mbt repeat alleles produce stable SCM proteins that associate with normal sites in polytene chromosomes. We also analyzed progeny from Scm mutant germline clones to compare the effects of an mbt repeat mutation during embryonic vs. pupal development. We suggest that the mbt repeat alleles produce altered SCM proteins that incorporate into and impair function of PcG protein complexes. PMID:9755199

  14. Setting limits on homeotic gene function: restraint of Sex combs reduced activity by teashirt and other homeotic genes.

    PubMed Central

    Andrew, D J; Horner, M A; Petitt, M G; Smolik, S M; Scott, M P

    1994-01-01

    Each of the homeotic genes of the HOM or HOX complexes is expressed in a limited domain along the anterior-posterior axis. Each homeotic protein directs the formation of characteristic structures, such as wings or ribs. In flies, when a heat shock-inducible homeotic gene is used to produce a homeotic protein in all cells of the embryo, only some cells respond by altering their fates. We have identified genes that limit where the homeotic gene Sex combs reduced (Scr) can affect cell fates in the Drosophila embryo. In the abdominal cuticle Scr is prevented from inducing prothoracic structures by the three bithorax complex (BX-C) homeotic genes. However, two of the BX-C homeotic genes, Ultrabithorax (Ubx) and abdominal-A (abd-A), have no effect on the ability of Scr to direct the formation of salivary glands. Instead, salivary gland induction by Scr is limited in the trunk by the homeotic gene teashirt (tsh) and in the last abdominal segment by the third BX-C gene, Abdominal-B (AbdB). Therefore, spatial restrictions on homeotic gene activity differ between tissues and result both from the regulation of homeotic gene transcription and from restraints on where homeotic proteins can function. Images PMID:7907545

  15. The product of the murine homolog of the Drosophila extra sex combs gene displays transcriptional repressor activity.

    PubMed Central

    Denisenko, O N; Bomsztyk, K

    1997-01-01

    The heterogeneous nuclear ribonucleoprotein K protein represents a novel class of proteins that may act as docking platforms that orchestrate cross-talk among molecules involved in signal transduction and gene expression. Using a fragment of K protein as bait in the yeast two-hybrid screen, we isolated a cDNA that encodes a protein whose primary structure has extensive similarity to the Drosophila melanogaster extra sex combs (esc) gene product, Esc, a putative silencer of homeotic genes. The cDNA that we isolated is identical to the cDNA of the recently positionally cloned mouse embryonic ectoderm development gene, eed. Like Esc, Eed contains six WD-40 repeats in the C-terminal half of the protein and is thought to repress homeotic gene expression during mouse embryogenesis. Eed binds to K protein through a domain in its N terminus, but interestingly, this domain is not found in the Drosophila Esc. Gal4-Eed fusion protein represses transcription of a reporter gene driven by a promoter that contains Gal4-binding DNA elements. Eed also represses transcription when recruited to a target promoter by Gal4-K protein. Point mutations within the eed gene that are responsible for severe embryonic development abnormalities abolished the transcriptional repressor activity of Eed. Results of this study suggest that Eed-restricted homeotic gene expression during embryogenesis reflects the action of Eed as a transcriptional repressor. The Eed-mediated transcriptional effects are likely to reflect the interaction of Eed with multiple molecular partners, including K protein. PMID:9234727

  16. Identification of polycomb and trithorax group responsive elements in the regulatory region of the Drosophila homeotic gene Sex combs reduced

    SciTech Connect

    Gindhart, J.G. Jr.; Kaufman, T.C.

    1995-02-01

    The Drosophilia homeotic gene Sex combs reduced (Scr) is necessary for the establishment and maintenance of the morphological identity of the labial and prothoracic segments. In the early embryo, its expression pattern is established through the activity of several gap and segmentation gene products, as well as other transcription factors. Once established, the Polycomb group (Pc-G) and trithorax group (trx-G) gene products maintain the spatial pattern of Scr expression for the remainder of development. We report the identification of DNA fragments in the Scr regulatory region that may be important for its regulation by Polycomb and trithorax group gene products. When DNA fragments containing these regulatory sequences are subcloned into P-element vectors containing a white minigene, transformants containing these constructs exhibit mosaic patterns of pigmentation in the adult eye, indicating that white minigene expression is repressed in a clonally heritable manner. The size of pigmented and nonpigmented clones in the adult eye suggests that the event determining whether a cell in the eye anlagen will express white occurs at least as early as the first larval instar. The amount of white minigene repression is reduced in some Polycomb group mutants, whereas repression is enhanced in flies mutant for a subset of trithorax group loci. The repressor activity of one fragment, normally located in Scr Intron 2, is increased when it is able to homologously pair, a property consistent with genetic data suggesting that Scr exhibits transvection. Another Scr regulatory fragment, normally located 40 kb upstream of the Scr promoter, silences ectopic expression of an Scr-lacZ fusion gene in the embryo and does so in a Polycomb-dependent manner. We propose that the regulatory sequences located within these DNA fragments may normally mediate the regulation of Scr by proteins encoded by members of Polycomb and trithorax group loci. 98 refs., 6 figs., 4 tabs.

  17. Sex comb on midleg (Scm) is a functional link between PcG-repressive complexes in Drosophila

    PubMed Central

    Kang, Hyuckjoon; McElroy, Kyle A.; Jung, Youngsook Lucy; Alekseyenko, Artyom A.; Zee, Barry M.; Park, Peter J.

    2015-01-01

    The Polycomb group (PcG) proteins are key regulators of development in Drosophila and are strongly implicated in human health and disease. How PcG complexes form repressive chromatin domains remains unclear. Using cross-linked affinity purifications of BioTAP-Polycomb (Pc) or BioTAP-Enhancer of zeste [E(z)], we captured all PcG-repressive complex 1 (PRC1) or PRC2 core components and Sex comb on midleg (Scm) as the only protein strongly enriched with both complexes. Although previously not linked to PRC2, we confirmed direct binding of Scm and PRC2 using recombinant protein expression and colocalization of Scm with PRC1, PRC2, and H3K27me3 in embryos and cultured cells using ChIP-seq (chromatin immunoprecipitation [ChIP] combined with deep sequencing). Furthermore, we found that RNAi knockdown of Scm and overexpression of the dominant-negative Scm-SAM (sterile α motif) domain both affected the binding pattern of E(z) on polytene chromosomes. Aberrant localization of the Scm-SAM domain in long contiguous regions on polytene chromosomes revealed its independent ability to spread on chromatin, consistent with its previously described ability to oligomerize in vitro. Pull-downs of BioTAP-Scm captured PRC1 and PRC2 and additional repressive complexes, including PhoRC, LINT, and CtBP. We propose that Scm is a key mediator connecting PRC1, PRC2, and transcriptional silencing. Combined with previous structural and genetic analyses, our results strongly suggest that Scm coordinates PcG complexes and polymerizes to produce broad domains of PcG silencing. PMID:26063573

  18. Identification of Polycomb and Trithorax Group Responsive Elements in the Regulatory Region of the Drosophila Homeotic Gene Sex Combs Reduced

    PubMed Central

    Gindhart-Jr., J. G.; Kaufman, T. C.

    1995-01-01

    The Drosophila homeotic gene Sex combs reduced (Scr) is necessary for the establishment and maintenance of the morphological identity of the labial and prothoracic segments. In the early embryo, its expression pattern is established through the activity of several gap and segmentation gene products, as well as other transcription factors. Once established, the Polycomb group (Pc-G) and trithorax group (trx-G) gene products maintain the spatial pattern of Scr expression for the remainder of development. We report the identification of DNA fragments in the Scr regulatory region that may be important for its regulation by Polycomb and trithorax group gene products. When DNA fragments containing these regulatory sequences are subcloned into P-element vectors containing a white minigene, transformants containing these constructs exhibit mosaic patterns of pigmentation in the adult eye, indicating that white minigene expression is repressed in a clonally heritable manner. The size of pigmented and nonpigmented clones in the adult eye suggests that the event determining whether a cell in the eye anlagen will express white occurs at least as early as the first larval instar. The amount of white minigene repression is reduced in some Polycomb group mutants, whereas repression is enhanced in flies mutant for a subset of trithorax group loci. The repressor activity of one fragment, normally located in Scr Intron 2, is increased when it is able to homologously pair, a property consistent with genetic data suggesting that Scr exhibits transvection. Another Scr regulatory fragment, normally located 40 kb upstream of the Scr promoter, silences ectopic expression of an Scr-lacZ fusion gene in the embryo and does so in a Polycomb-dependent manner. We propose that the regulatory sequences located within these DNA fragments may normally mediate the regulation of Scr by proteins encoded by members of the Polycomb and trithorax group loci. PMID:7713433

  19. Identification of SCML2, a second human gene homologous to the Drosophila sex comb on midleg (Scm): A new gene cluster on Xp22.

    PubMed

    Montini, E; Buchner, G; Spalluto, C; Andolfi, G; Caruso, A; den Dunnen, J T; Trump, D; Rocchi, M; Ballabio, A; Franco, B

    1999-05-15

    We have identified a novel gene with homologies to the Drosophila Sex comb on midleg (Scm) gene from the short arm of the X chromosome. Scm is a member of the Polycomb group (PcG) genes, which encode transcriptional repressors essential for appropriate development in the fly and in mammals. The newly identified transcript named SCML2 (sex comb on midleg like-2, HGMW-approved symbol) is ubiquitously expressed and encodes a protein of 700 amino acids. SCML2 maps very close to the recently identified SCML1, revealing the presence of a new gene cluster in Xp22. The homology and map location identify SCML2 as a candidate gene for Xp22-linked developmental disorders, including the oral-facial-digital type I (OFDI) syndrome. A study of the SCML1-SCML2 cluster in primates indicates that the two genes are localized to the same region in Old World monkeys, New World monkeys, and prosimians, suggesting that the duplication event leading to the formation of the SCML cluster on Xp22 occurred before primate divergence. PMID:10331946

  20. Acquisition of a leucine zipper motif as a mechanism of antimorphy for an allele of the Drosophila Hox gene Sex combs reduced.

    PubMed

    Sivanantharajah, Lovesha; Percival-Smith, Anthony

    2014-05-01

    In 1932, Müller first used the term "antimorphic" to describe mutant alleles that have an effect that is antagonistic to that of the wild-type allele from which they were derived. In a previous characterization of mutant alleles of the Drosophila melanogaster Hox gene, Sex combs reduced (Scr), we identified the missense, antimorphic allele Scr(14), which is a Ser10-to-Leu change in the N-terminally located, bilateran-specific octapeptide motif. Here we propose that the cause of Scr(14) antimorphy is the acquisition of a leucine zipper oligomerization motif spanning the octapeptide motif and adjacently located protostome-specific LASCY motif. Analysis of the primary and predicted secondary structures of the SCR N-terminus suggests that while the SCR(+) encodes a short, α-helical region containing one putative heptad repeat, the same region in SCR(14) encodes a longer, α-helical region containing two putative heptad repeats. In addition, in vitro cross-linking assays demonstrated strong oligomerization of SCR(14) but not SCR(+). For in vivo sex comb formation, we observed reciprocal inhibition of endogenous SCR(+) and SCR(14) activity by ectopic expression of truncated SCR(14) and SCR(+) peptides, respectively. The acquisition of an oligomerization domain in SCR(14) presents a novel mechanism of antimorphy relative to the dominant negative mechanism, which maintains oligomerization between the wild-type and mutant protein subunits. PMID:24622333

  1. Chemical order in the glassy AsxS1-x system: An x-ray-absorption spectroscopy study

    NASA Astrophysics Data System (ADS)

    Yang, C. Y.; Paesler, M. A.; Sayers, D. E.

    1989-05-01

    We have examined chemical ordering in the glassy AsxS1-x system by determining the effect of composition on the local structure of these chalcogenide glasses using x-ray-absorption spectroscopy. Structural changes associated with composition indicate that with increasing S content, the S-rich glasses on the As site have a similar local structure to crystalline As2S3 (orpiment), but the As-S-As linkages are replaced by As-S-S linkages at higher S concentration. In As-rich glasses a breakdown of the local AsS3 configuration is evident and the formation of As-As bonds is observed. Further comparison between As-rich alloys and crystalline As4S4 (realgar) suggests that a significant fraction of disordered As4S4 molecular fragments is contained in the As-rich region.

  2. Compact electrostatic comb actuator

    DOEpatents

    Rodgers, M. Steven; Burg, Michael S.; Jensen, Brian D.; Miller, Samuel L.; Barnes, Stephen M.

    2000-01-01

    A compact electrostatic comb actuator is disclosed for microelectromechanical (MEM) applications. The actuator is based upon a plurality of meshed electrostatic combs, some of which are stationary and others of which are moveable. One or more restoring springs are fabricated within an outline of the electrostatic combs (i.e. superposed with the moveable electrostatic combs) to considerably reduce the space required for the actuator. Additionally, a truss structure is provided to support the moveable electrostatic combs and prevent bending or distortion of these combs due to unbalanced electrostatic forces or external loading. The truss structure formed about the moveable electrostatic combs allows the spacing between the interdigitated fingers of the combs to be reduced to about one micron or less, thereby substantially increasing the number of active fingers which can be provided in a given area. Finally, electrostatic shields can be used in the actuator to substantially reduce unwanted electrostatic fields to further improve performance of the device. As a result, the compact electrostatic comb actuator of the present invention occupies only a fraction of the space required for conventional electrostatic comb actuators, while providing a substantial increase in the available drive force (up to one-hundred times).

  3. Comb and brush acne.

    PubMed

    Petrozzi, J W

    1980-12-01

    Frequent combing or brushing of the hair may result in an exacerbation of existing acne or be the cause of localized acne. Because of today's hair styling habits and methods, this type of acne is commonly encountered but poorly appreciated by physicians. Patient education is the most important factor in the management of this condition. Comb and brush acne is another external factor to be added to the list of causes of "acne mechanica." PMID:6449356

  4. Dynamics of comb-of-comb networks

    NASA Astrophysics Data System (ADS)

    Liu, Hongxiao; Lin, Yuan; Dolgushev, Maxim; Zhang, Zhongzhi

    2016-03-01

    The dynamics of complex networks, a current hot topic in many scientific fields, is often coded through the corresponding Laplacian matrix. The spectrum of this matrix carries the main features of the networks' dynamics. Here we consider the deterministic networks which can be viewed as "comb-of-comb" iterative structures. For their Laplacian spectra we find analytical equations involving Chebyshev polynomials whose properties allow one to analyze the spectra in deep. Here, in particular, we find that in the infinite size limit the corresponding spectral dimension goes as ds→2 . The ds leaves its fingerprint on many dynamical processes, as we exemplarily show by considering the dynamical properties of polymer networks, including single monomer displacement under a constant force, mechanical relaxation, and fluorescence depolarization.

  5. Frequency comb swept lasers

    PubMed Central

    Tsai, Tsung-Han; Zhou, Chao; Adler, Desmond C.; Fujimoto, James G.

    2010-01-01

    We demonstrate a frequency comb (FC) swept laser and a frequency comb Fourier domain mode locked (FC-FDML) laser for applications in optical coherence tomography (OCT). The fiber-based FC swept lasers operate at a sweep rate of 1kHz and 120kHz, respectively over a 135nm tuning range centered at 1310nm with average output powers of 50mW. A 25GHz free spectral range frequency comb filter in the swept lasers causes the lasers to generate a series of well defined frequency steps. The narrow bandwidth (0.015nm) of the frequency comb filter enables a ~?1.2dB sensitivity roll off over ~3mm range, compared to conventional swept source and FDML lasers which have ?10dB and ?5dB roll offs, respectively. Measurements at very long ranges are possible with minimal sensitivity loss, however reflections from outside the principal measurement range of 03mm appear aliased back into the principal range. In addition, the frequency comb output from the lasers are equally spaced in frequency (linear in k-space). The filtered laser output can be used to self-clock the OCT interference signal sampling, enabling direct fast Fourier transformation of the fringe signals, without the need for fringe recalibration procedures. The design and operation principles of FC swept lasers are discussed and designs for short cavity lasers for OCT and interferometric measurement applications are proposed. PMID:19997365

  6. Microwave Comb Generator

    NASA Technical Reports Server (NTRS)

    Sigman, E. H.

    1989-01-01

    Stable reference tones aid testing and calibration of microwave receivers. Signal generator puts out stable tones in frequency range of 2 to 10 GHz at all multiples of reference input frequency, at any frequency up to 1 MHz. Called "comb generator" because spectral plot resembles comb. DC reverse-bias current switched on and off at 1 MHz to generate sharp pulses in step-recovery diode. Microwave components mounted on back of special connector containing built-in attenuator. Used in testing microwave and spread-spectrum wide-band receivers.

  7. Tellurium n-type doping of highly mismatched amorphous GaN1-xAsx alloys in plasma-assisted molecular beam epitaxy

    NASA Astrophysics Data System (ADS)

    Novikov, S. V.; Ting, M.; Yu, K. M.; Sarney, W. L.; Martin, R. W.; Svensson, S. P.; Walukiewicz, W.; Foxon, C. T.

    2014-10-01

    In this paper we report our study on n-type Te doping of amorphous GaN1-xAsx layers grown by plasma-assisted molecular beam epitaxy. We have used a low temperature PbTe source as a source of tellurium. Reproducible and uniform tellurium incorporation in amorphous GaN1-xAsx layers has been successfully achieved with a maximum Te concentration of 9×1020 cm-3. Tellurium incorporation resulted in n-doping of GaN1-xAsx layers with Hall carrier concentrations up to 3×1019 cm-3 and mobilities of ~1 cm2/V s. The optimal growth temperature window for efficient Te doping of the amorphous GaN1-xAsx layers has been determined.

  8. Tellurium n-type doping of highly mismatched amorphous GaN1-xAsx alloys in plasma-assisted molecular beam epitaxy

    DOE PAGESBeta

    Novikov, S. V.; Ting, M.; Yu, K. M.; Sarney, W. L.; Martin, R. W.; Svensson, S. P.; Walukiewicz, W.; Foxon, C. T.

    2014-10-01

    In this paper we report our study on n-type Te doping of amorphous GaN1-xAsx layers grown by plasma-assisted molecular beam epitaxy. We have used a low temperature PbTe source as a source of tellurium. Reproducible and uniform tellurium incorporation in amorphous GaN1-xAsx layers has been successfully achieved with a maximum Te concentration of 9×10²⁰ cm⁻³. Tellurium incorporation resulted in n-doping of GaN1-xAsx layers with Hall carrier concentrations up to 3×10¹⁹ cm⁻³ and mobilities of ~1 cm²/V s. The optimal growth temperature window for efficient Te doping of the amorphous GaN1-xAsx layers has been determined.

  9. Dual-comb MIXSEL

    NASA Astrophysics Data System (ADS)

    Link, S. M.; Zaugg, C. A.; Klenner, A.; Mangold, M.; Golling, M.; Tilma, B. W.; Keller, U.

    2015-03-01

    We present a single semiconductor disk laser simultaneously emitting two different gigahertz modelocked pulse trains. A birefringent crystal inside a modelocked integrated external-cavity surface-emitting laser (MIXSEL) separates the cavity beam into two spatially separated beams with perpendicular polarizations on the MIXSEL chip. This MIXSEL then generates two orthogonally polarized collinear modelocked pulse trains from one simple straight cavity. Superimposing the beams on a photo detector creates a microwave beat signal, representing a strikingly simple setup to down-convert the terahertz optical frequencies into the electronically accessible microwave regime. This makes the dual-comb MIXSEL scheme an ultra-compact and cost-efficient candidate for dual-comb spectroscopy applications.

  10. Spectrally resolved frequency comb interferometry

    NASA Astrophysics Data System (ADS)

    van den Berg, S.

    2014-04-01

    In this contribution a novel method for interferometric distance measurement is presented, that is based on unraveling the spectrum of a femtosecond frequency comb. The light of a frequency comb is sent into a Michelson interferometer. The output of the interferometer is analyzed by a high-resolution spectrometer, resolving the individual comb modes. The path-length difference between the two arms is determined on the level of tens of nm, by utilizing the wealth of information present in the unraveled spectrum, showing homodyne interference for each individual frequency comb mode. The measurement method allows for high-accuracy measurements in combination with a large range of non-ambiguity.

  11. The gap structure of BaFe2(AsxP1-x)2 determined from specific heat measurements

    NASA Astrophysics Data System (ADS)

    Malone, L.; Mizukami, Y.; Walmsley, P.; Putzke, C.; Kasahara, S.; Terashima, T.; Shibauchi, T.; Matsuda, Y.; Carrington, A.

    2014-03-01

    The structure of the superconducting gap of the pncitide superconductors is an unresolved but crucial issue to understanding their mechanism of superconductivity. While some experiments and theories support a fully gapped s+/s- state, several experiments have revealed evidence for nodes in some families of pnictides. Detailed knowledge of the superconducting gap structure and how it varies as a function of material properties can be useful in helping to decide between microscopic theories. BaFe2(AsxP1-x)2 is a pnictide family with a nodal gap structure and evidence for quantum critical behavior. We have measured the specific heat of several samples of BaFe2(AsxP1-x)2 in a range of x values. We examine the temperature, field and field angle dependence of the specific heat to deduce the changes in the superconducting gap structure as the material is tuned to the quantum critical point.

  12. Hair breakage during combing. IV. Brushing and combing hair.

    PubMed

    Robbins, Clarence; Kamath, Yash

    2007-01-01

    During combing of hair, longer fiber breaks (>2.5 cm) occur principally by impact loading of looped crossover hairs, while short segment breaks (<2.5 cm) occur primarily by end wrapping. Brushing provides breakage similarly but with a higher ratio of long-to-short segment breaks, and the ratio of long-to-short segment breaks (L/S) is a good way to follow these two pathways of breakage under different conditions. For example, bleaching hair, a longer comb stroke, increasing fiber curvature, wet combing versus dry combing, and brushing versus combing all provide for an increase in long segment breaks and this ratio, with the largest effect produced by brushing. PMID:18305876

  13. Coarse frequency comb interferometry

    NASA Astrophysics Data System (ADS)

    Schwider, J.

    2008-08-01

    Real wedge interferometers of the Fizeau-type do not allow for fringes in case of a spectral broad band source - or in short: for white light fringes. Here, the use of a suitable frequency comb source will help to overcome this limitation on the one hand and on the other will offer the capability for enhanced phase sensitivity in high precision measurements of surface deviations. Frequency combs can be produced either by using a pulse train from a fs-laser or by passive filtering of the light emitted by a broad band source as a superlum-diode or a fs-laser. The frequency comb produced by a common fs-laser is extremely fine, i.e., the frequency difference of consecutive peaks is very small or the distance of consecutive pulses of the pulse train might be of the order of 1m. Therefore, the coarse pulse train produced by passive filtering of a broad band source is better adapted to the needs of surface testing interferometers. White light fringes are either applied for the profiling of discontinuous surfaces and/or can serve as an indication for the correct choice of multiplication factors in superposition interferometry. During the last decennium it became more and more clear that spatially incoherent sources provide better measuring accuracy in surface measurements due to the reduced influence of dust diffraction patterns. The advantage of laser illumination can nevertheless be maintained if the laser light is made spatially incoherent through moving scatterers in the light path. Here, we will discuss the application of spatially incoherent broad band light frequency filtered through a Fabry-Perot filter. The main applications are in the following fields: (1) surface profiling applications using two-beam Fizeau interferometers, (2) selection of single cavities out of a series of interlaced cavities, and (3) sensitivity enhancement for multi-beam interferometers for planeness or sphericity measurements. Some of the discussed possibilities will be experimentally demonstrated.

  14. Molecular Comb Development

    SciTech Connect

    Ferrell, T.L.; Thundat, G.T.; Witkowski, C.E., III

    2007-07-17

    This CRADA was developed to enable ORNL to assist Protein Discovery, Inc. to develop a novel biomolecular separation system based on an ORNL patent application 'Photoelectrochemical Molecular Comb' by Thundat, Ferrell, and Brown. The Molecular Comb concept is based on creating light-induced charge carriers at a semiconductor-liquid interface, which is kept at a potential control such that a depletion layer is formed in the semiconductor. Focusing light from a low-power illumination source creates electron-hole pairs, which get separated in the depletion layer. The light-induced charge carriers reaching the surface attract oppositely charged biomolecules present in the solution. The solution is a buffer solution with very small concentrations of biomolecules. As the focused light is moved across the surface of the semiconductor-liquid interface, the accumulated biomolecules follow the light beam. A thin layer of gel or other similar material on the surface of the semiconductor can act as a sieving medium for separating the biomolecules according to their sizes.

  15. Material properties and modeling characteristics for MnFeP1-xAsx materials for application in magnetic refrigeration

    NASA Astrophysics Data System (ADS)

    Engelbrecht, K.; Nielsen, K. K.; Bahl, C. R. H.; Carroll, C. P.; van Asten, D.

    2013-05-01

    Compounds of MnFeP1-xAsx have received attention recently for their use in active magnetic regenerators (AMR) because of their relatively high isothermal entropy change and adiabatic temperature change with magnetization. However, the materials also generally exhibit a significant magnetic and thermal hysteresis, and it is not well understood how the hysteresis will affect performance in a practical AMR device. The amount of hysteresis shown by a material can be controlled to an extent by tuning the processing conditions used during material synthesis; therefore, knowledge of the practical impact of hysteresis is a key element to guide successful material development and synthesis. The properties of a magnetocaloric MnFeP1-xAsx compound are characterized as a function of temperature and applied magnetic field, and the results are used to assess the effects of hysteresis on magnetocaloric properties. Different methods of building property functions from the measured specific heat, magnetization, and adiabatic temperature change are presented. It is shown that model predictions can be highly dependent on how the properties that are used by the AMR model are calculated.

  16. Quantum spin Hall insulators in functionalized arsenene (AsX, X = F, OH and CH3) monolayers with pronounced light absorption.

    PubMed

    Zhao, Jun; Li, Yanle; Ma, Jing

    2016-05-14

    The search for new two-dimensional topological insulators (2D-TIs) with large band gaps is of great interest and importance. Our first-principles calculations predicted three candidates for 2D-TIs, arsenene functionalized with F, OH and CH3 groups (AsX, X = F, OH and CH3), which preserved large bulk band gaps from 100 to 160 meV (up to 260 meV) derived from the spin-orbit coupling (SOC) within the px,y orbitals. This picture is similar to what was reported for an AsH monolayer with a band gap of 193 meV. Ab initio molecular dynamic (AIMD) simulations demonstrated the thermal stabilities of the AsX monolayers even at 500 K. The nontrivial topological phase was confirmed by the topological invariant Z2 and topological edge state. The topological electronic bandgap of the AsF monolayer can be effectively modulated by biaxial tensile strain and vertical external electric field. In addition, pronounced light absorption in the near-infrared and visible range of the solar spectrum was expected for the AsX (X = H, F) monolayers from the adsorption peaks at 0.45-1.6 eV, which is attractive for light harvesting. The nontrivial quantum spin Hall (QSH) insulators AsX could be promising candidates for practical room-temperature applications in dissipationless transport devices and photovoltaics. PMID:27101795

  17. Visible wavelength astro-comb.

    PubMed

    Benedick, Andrew J; Chang, Guoqing; Birge, Jonathan R; Chen, Li-Jin; Glenday, Alexander G; Li, Chih-Hao; Phillips, David F; Szentgyorgyi, Andrew; Korzennik, Sylvain; Furesz, Gabor; Walsworth, Ronald L; Krtner, Franz X

    2010-08-30

    We demonstrate a tunable laser frequency comb operating near 420 nm with mode spacing of 20-50 GHz, usable bandwidth of 15 nm and output power per line of ~20 nW. Using the TRES spectrograph at the Fred Lawrence Whipple Observatory, we characterize this system to an accuracy below 1m/s, suitable for calibrating high-resolution astrophysical spectrographs used, e.g., in exoplanet studies. PMID:20940813

  18. On-chip dual-comb based on quantum cascade laser frequency combs

    NASA Astrophysics Data System (ADS)

    Villares, G.; Wolf, J.; Kazakov, D.; Süess, M. J.; Hugi, A.; Beck, M.; Faist, J.

    2015-12-01

    Dual-comb spectroscopy is emerging as an appealing application of mid-infrared frequency combs for high-resolution molecular spectroscopy, as it leverages on the unique coherence properties of frequency combs. Here, we present an on-chip dual-comb source based on mid-infrared quantum cascade laser frequency combs. Control of the combs repetition and offset frequencies is obtained by integrating micro-heaters next to each laser. We show that a full control of the dual-comb system is possible, by measuring a multi-heterodyne beating corresponding to an optical bandwidth of 32 cm-1 centered at 1330 cm-1 (7.52 μm), demonstrating that this device represents a critical step towards compact dual-comb systems.

  19. On-chip dual-comb based on quantum cascade laser frequency combs

    SciTech Connect

    Villares, G. Wolf, J.; Kazakov, D.; Süess, M. J.; Beck, M.; Faist, J.; Hugi, A.

    2015-12-21

    Dual-comb spectroscopy is emerging as an appealing application of mid-infrared frequency combs for high-resolution molecular spectroscopy, as it leverages on the unique coherence properties of frequency combs. Here, we present an on-chip dual-comb source based on mid-infrared quantum cascade laser frequency combs. Control of the combs repetition and offset frequencies is obtained by integrating micro-heaters next to each laser. We show that a full control of the dual-comb system is possible, by measuring a multi-heterodyne beating corresponding to an optical bandwidth of 32 cm{sup −1} centered at 1330 cm{sup −1} (7.52 μm), demonstrating that this device represents a critical step towards compact dual-comb systems.

  20. A Josephson radiation comb generator

    NASA Astrophysics Data System (ADS)

    Solinas, P.; Gasparinetti, S.; Golubev, D.; Giazotto, F.

    2015-07-01

    We propose the implementation of a Josephson Radiation Comb Generator (JRCG) based on a dc superconducting quantum interference device (SQUID) driven by an external magnetic field. When the magnetic flux crosses a diffraction node of the critical current interference pattern, the superconducting phase undergoes a jump of π and a voltage pulse is generated at the extremes of the SQUID. Under periodic drive this allows one to generate a sequence of sharp, evenly spaced voltage pulses. In the frequency domain, this corresponds to a comb-like structure similar to the one exploited in optics and metrology. With this device it is possible to generate up to several hundreds of harmonics of the driving frequency. For example, a chain of 50 identical high-critical-temperature SQUIDs driven at 1 GHz can deliver up to a 0.5 nW at 200 GHz. The availability of a fully solid-state radiation comb generator such as the JRCG, easily integrable on chip, may pave the way to a number of technological applications, from metrology to sub-millimeter wave generation.

  1. A Josephson radiation comb generator.

    PubMed

    Solinas, P; Gasparinetti, S; Golubev, D; Giazotto, F

    2015-01-01

    We propose the implementation of a Josephson Radiation Comb Generator (JRCG) based on a dc superconducting quantum interference device (SQUID) driven by an external magnetic field. When the magnetic flux crosses a diffraction node of the critical current interference pattern, the superconducting phase undergoes a jump of π and a voltage pulse is generated at the extremes of the SQUID. Under periodic drive this allows one to generate a sequence of sharp, evenly spaced voltage pulses. In the frequency domain, this corresponds to a comb-like structure similar to the one exploited in optics and metrology. With this device it is possible to generate up to several hundreds of harmonics of the driving frequency. For example, a chain of 50 identical high-critical-temperature SQUIDs driven at 1 GHz can deliver up to a 0.5 nW at 200 GHz. The availability of a fully solid-state radiation comb generator such as the JRCG, easily integrable on chip, may pave the way to a number of technological applications, from metrology to sub-millimeter wave generation. PMID:26193628

  2. A Josephson radiation comb generator

    PubMed Central

    Solinas, P.; Gasparinetti, S.; Golubev, D.; Giazotto, F.

    2015-01-01

    We propose the implementation of a Josephson Radiation Comb Generator (JRCG) based on a dc superconducting quantum interference device (SQUID) driven by an external magnetic field. When the magnetic flux crosses a diffraction node of the critical current interference pattern, the superconducting phase undergoes a jump of π and a voltage pulse is generated at the extremes of the SQUID. Under periodic drive this allows one to generate a sequence of sharp, evenly spaced voltage pulses. In the frequency domain, this corresponds to a comb-like structure similar to the one exploited in optics and metrology. With this device it is possible to generate up to several hundreds of harmonics of the driving frequency. For example, a chain of 50 identical high-critical-temperature SQUIDs driven at 1 GHz can deliver up to a 0.5 nW at 200 GHz. The availability of a fully solid-state radiation comb generator such as the JRCG, easily integrable on chip, may pave the way to a number of technological applications, from metrology to sub-millimeter wave generation. PMID:26193628

  3. Charge carrier localization effects on the quantum efficiency and operating temperature range of InAsxP1-x/InP quantum well detectors

    NASA Astrophysics Data System (ADS)

    Vashisht, Geetanjali; Dixit, V. K.; Porwal, S.; Kumar, R.; Sharma, T. K.; Oak, S. M.

    2016-03-01

    The effect of charge carrier localization resulting in "S-shaped" temperature dependence of the photoluminescence peak energy of InAsxP1-x/InP quantum wells (QWs) is distinctly revealed by the temperature dependent surface photo voltage (SPV) and photoconductivity (PC) processes. It is observed that the escape efficiency of carriers from QWs depends on the localization energy, where the carriers are unable to contribute in SPV/PC signal below a critical temperature. Below the critical temperature, carriers are strongly trapped in the localized states and are therefore unable to escape from the QW. Further, the critical temperature increases with the magnitude of localization energy of carriers. Carrier localization thus plays a pivotal role in defining the operating temperature range of InAsxP1-x/InP QW detectors.

  4. Quantum spin Hall insulators in functionalized arsenene (AsX, X = F, OH and CH3) monolayers with pronounced light absorption

    NASA Astrophysics Data System (ADS)

    Zhao, Jun; Li, Yanle; Ma, Jing

    2016-05-01

    The search for new two-dimensional topological insulators (2D-TIs) with large band gaps is of great interest and importance. Our first-principles calculations predicted three candidates for 2D-TIs, arsenene functionalized with F, OH and CH3 groups (AsX, X = F, OH and CH3), which preserved large bulk band gaps from 100 to 160 meV (up to 260 meV) derived from the spin-orbit coupling (SOC) within the px,y orbitals. This picture is similar to what was reported for an AsH monolayer with a band gap of 193 meV. Ab initio molecular dynamic (AIMD) simulations demonstrated the thermal stabilities of the AsX monolayers even at 500 K. The nontrivial topological phase was confirmed by the topological invariant Z2 and topological edge state. The topological electronic bandgap of the AsF monolayer can be effectively modulated by biaxial tensile strain and vertical external electric field. In addition, pronounced light absorption in the near-infrared and visible range of the solar spectrum was expected for the AsX (X = H, F) monolayers from the adsorption peaks at 0.45-1.6 eV, which is attractive for light harvesting. The nontrivial quantum spin Hall (QSH) insulators AsX could be promising candidates for practical room-temperature applications in dissipationless transport devices and photovoltaics.The search for new two-dimensional topological insulators (2D-TIs) with large band gaps is of great interest and importance. Our first-principles calculations predicted three candidates for 2D-TIs, arsenene functionalized with F, OH and CH3 groups (AsX, X = F, OH and CH3), which preserved large bulk band gaps from 100 to 160 meV (up to 260 meV) derived from the spin-orbit coupling (SOC) within the px,y orbitals. This picture is similar to what was reported for an AsH monolayer with a band gap of 193 meV. Ab initio molecular dynamic (AIMD) simulations demonstrated the thermal stabilities of the AsX monolayers even at 500 K. The nontrivial topological phase was confirmed by the topological invariant Z2 and topological edge state. The topological electronic bandgap of the AsF monolayer can be effectively modulated by biaxial tensile strain and vertical external electric field. In addition, pronounced light absorption in the near-infrared and visible range of the solar spectrum was expected for the AsX (X = H, F) monolayers from the adsorption peaks at 0.45-1.6 eV, which is attractive for light harvesting. The nontrivial quantum spin Hall (QSH) insulators AsX could be promising candidates for practical room-temperature applications in dissipationless transport devices and photovoltaics. Electronic supplementary information (ESI) available. See DOI: 10.1039/c6nr01683a

  5. Atomic quantum memory for multimode frequency combs

    NASA Astrophysics Data System (ADS)

    Zheng, Zhan; Mishina, Oxana; Treps, Nicolas; Fabre, Claude

    2015-03-01

    We propose a Raman quantum memory scheme that uses several atomic ensembles to store and retrieve the multimode highly entangled state of an optical quantum frequency comb, such as the one produced by parametric down-conversion of a pump frequency comb. We analyze the efficiency and the fidelity of such a quantum memory. Results show that our proposal may be helpful to multimode information processing using the different frequency bands of an optical frequency comb.

  6. Scaling of Yb-Fiber Frequency Combs

    NASA Astrophysics Data System (ADS)

    Ruehl, Axel; Marcinkevicius, Andrius; Fermann, Martin E.; Hartl, Ingmar

    2010-06-01

    Immediately after their introduction in 1999, femtosecond laser frequency combs revolutionized the field of precision optical frequency metrology and are key elements in many experiments. Frequency combs based on femtosecond Er-fiber lasers based were demonstrated in 2005, allowing additionally rugged, compact set-ups and reliable unattended long-term operation. The introduction of Yb-fiber technology led to an dramatic improvement in fiber-comb performance in various aspects. Low-noise Yb-fiber femtosecond oscillators enabled a reduction of relative comb tooth linewidth to the sub-Hz level as well as scaling of the fundamental comb spacings up to 1 GHz. This is beneficial for any frequency-domain comb application due to the higher power per comb-mode. Many spectroscopic applications require, however, frequency combs way beyond the wavelength range accessible with broad band laser materials, so nonlinear conversion and hence higher peak intensity is required. We demonstrated power scaling of Yb-fiber frequency combs up to 80 W average power in a strictly linear chirped-pulse amplification schemes compatible with low-noise phase control. These high-power Yb-fiber-frequency combs facilitated not only the extension to the mid-IR spectral region. When coupled to a passive enhancement cavity, the average power can be further scaled to the kW-level opening new capabilities for XUV frequency combs via high-harmonic generation. All these advances of fiber-based frequency combs will trigger many novel applications both in fundamental and applied sciences. Schibli et al., Nature Photonics 2 355 (2008). Hartl et al., MF9 in Advanced Solid-State Photonics. 2009, Optical Society of America. Ruehl et al., AWC7 in Advanced Solid-State Photonics. 2010, Optical Society of America. Adler et al., Optics Letters 34 1330 (2009). Yost et al., Nature Physics 5 815 (2009).

  7. Femtosecond laser comb based subterahertz synthesizer

    NASA Astrophysics Data System (ADS)

    Makarov, D. S.; Tretyakov, M. Yu.; Shkaev, A. P.; Kiselev, A. M.; Stepanov, A. N.; Parshin, V. V.

    2014-08-01

    Functioning layout of a frequency comb-based subterahertz synthesizer is demonstrated. A primary subterahertz oscillator was phase-locked against the Ti:Sapphire femtosecond laser frequency comb down-converted to the subterahertz range by the semiconductor mixer. Synthesizer operation is demonstrated through Fabri-Perot resonator response curve recording experiment. Spectral purity of the synthesizer was estimated. The advantage of the comb-based synthesizer over the synthesizer based on the Agilent E8257D device was shown.

  8. Dual-comb modelocked laser.

    PubMed

    Link, Sandro M; Klenner, Alexander; Mangold, Mario; Zaugg, Christian A; Golling, Matthias; Tilma, Bauke W; Keller, Ursula

    2015-03-01

    In this paper we present the first semiconductor disk laser (SDL) emitting simultaneously two collinearly overlapping cross-polarized gigahertz modelocked pulse trains with different pulse repetition rates. Using only a simple photo detector and a microwave spectrum analyzer directly down-converts the frequency comb difference from the optical to the microwave frequency domain. With this setup, the relative carrier-envelope-offset (CEO) frequency can be accessed directly without an f-to2f interferometer. A very compact design is obtained using the modelocked integrated external-cavity surface emitting laser (MIXSEL) which is part of the family of optically pumped SDLs and similar to a vertical external cavity surface emitting laser (VECSEL) but with both gain and saturable absorber integrated into the same semiconductor wafer (i.e. MIXSEL chip). We then simply added an additional intracavity birefringent crystal inside the linear straight cavity between the output coupler and the MIXSEL chip which splits the cavity beam into two collinear but spatially separated cross-polarized beams on the MIXSEL chip. This results in two modelocked collinear and fully overlapping cross-polarized output beams with adjustable pulse repetition frequencies with excellent noise performance. We stabilized both pulse repetition rates of the dual comb MIXSEL. PMID:25836785

  9. Femtosecond optical parametric oscillator frequency combs

    NASA Astrophysics Data System (ADS)

    Kobayashi, Yohei; Torizuka, Kenji; Marandi, Alireza; Byer, Robert L.; McCracken, Richard A.; Zhang, Zhaowei; Reid, Derryck T.

    2015-09-01

    Techniques to measure and manipulate the carrier-envelope phase within femtosecond optical parametric oscillators (OPOs) allow their outputs to be stabilized in a way that produces a frequency comb structure, potentially tunable throughout the transparency band of the gain material. In this review we describe the fundamental principles of phase control, on which the development of singly- and doubly-resonant OPO frequency combs is based. We give examples of practical embodiments of such combs, and discuss in detail several applications, including spectroscopy, metrology, quantum computation and astrophotonics.

  10. Fractional diffusion on a fractal grid comb

    NASA Astrophysics Data System (ADS)

    Sandev, Trifce; Iomin, Alexander; Kantz, Holger

    2015-03-01

    A grid comb model is a generalization of the well known comb model, and it consists of N backbones. For N =1 the system reduces to the comb model where subdiffusion takes place with the transport exponent 1 /2 . We present an exact analytical evaluation of the transport exponent of anomalous diffusion for finite and infinite number of backbones. We show that for an arbitrarily large but finite number of backbones the transport exponent does not change. Contrary to that, for an infinite number of backbones, the transport exponent depends on the fractal dimension of the backbone structure.

  11. Light beam frequency comb generator

    DOEpatents

    Priatko, Gordon J.; Kaskey, Jeffrey A.

    1992-01-01

    A light beam frequency comb generator uses an acousto-optic modulator to generate a plurality of light beams with frequencies which are uniformly separated and possess common noise and drift characteristics. A well collimated monochromatic input light beam is passed through this modulator to produce a set of both frequency shifted and unshifted optical beams. An optical system directs one or more frequency shifted beams along a path which is parallel to the path of the input light beam such that the frequency shifted beams are made incident on the modulator proximate to but separated from the point of incidence of the input light beam. After the beam is thus returned to and passed through the modulator repeatedly, a plurality of mutually parallel beams are generated which are frequency-shifted different numbers of times and possess common noise and drift characteristics.

  12. Light beam frequency comb generator

    DOEpatents

    Priatko, G.J.; Kaskey, J.A.

    1992-11-24

    A light beam frequency comb generator uses an acousto-optic modulator to generate a plurality of light beams with frequencies which are uniformly separated and possess common noise and drift characteristics. A well collimated monochromatic input light beam is passed through this modulator to produce a set of both frequency shifted and unshifted optical beams. An optical system directs one or more frequency shifted beams along a path which is parallel to the path of the input light beam such that the frequency shifted beams are made incident on the modulator proximate to but separated from the point of incidence of the input light beam. After the beam is thus returned to and passed through the modulator repeatedly, a plurality of mutually parallel beams are generated which are frequency-shifted different numbers of times and possess common noise and drift characteristics. 2 figs.

  13. Ultrabroadband coherent supercontinuum frequency comb

    SciTech Connect

    Ruehl, Axel; McKay, Hugh; Thomas, Brian; Dong, Liang; Fermann, Martin E.; Hartl, Ingmar; Martin, Michael J.; Cossel, Kevin C.; Chen Lisheng; Benko, Craig; Ye Jun; Dudley, John M.

    2011-07-15

    We present detailed studies of the coherence properties of an ultrabroadband supercontinuum, enabled by a comprehensive approach involving continuous-wave laser sources to independently probe both the amplitude and phase noise quadratures across the entire spectrum. The continuum coherently spans more than 1.5 octaves, supporting Hz-level comparison of ultrastable lasers at 698 nm and 1.54 {mu}m. We present a complete numerical simulation of the accumulated comb coherence in the limit of many pulses, in contrast to the single-pulse level, with systematic experimental verification. The experiment and numerical simulations reveal the presence of quantum-seeded broadband amplitude noise without phase coherence degradation, including the discovery of a dependence of the supercontinuum coherence on the fiber fractional Raman gain.

  14. Calculation of tunable type-II band alignments in InAsxSbyP1‑x‑y/InAs heterojunctions

    NASA Astrophysics Data System (ADS)

    Shim, Kyurhee

    2016-01-01

    The energy band gaps of the alloy InAsxSbyP1‑x‑y are calculated using the correlated function expansion (CFE) technique over the entire composition space x and y, for which the CFE band gap composition contour for the mid-infrared (MIR) spectral region of 2 (0.62)–5 µm (0.25 eV) is presented. The composition dependence of the valence-band maximum (VBM) is obtained using the universal tight binding (UTB) method, and the corresponding conduction-band minimum (CBM) can be computed from the difference between the band gap and the VBM. By organizing the relative positions of the VBM and CBM between the quaternary alloy InAsSbP and the binary compound InAs, the band alignments and band types of InAsSbP/InAs heterojunctions (HJs) along the lattice-matching conditions x and y [i.e., y = 0.311(1 ‑ x)] are determined. It is found that the VBMs of the alloy InAsxSbyP1‑x‑y are located within the band gap of InAs, whereas the CBMs of the alloy lie outside the band gap of InAs over the entire composition range. This implies that the InAsxSbyP1‑x‑y/InAs HJs exhibit composition-tunable, type-II (staggered) band alignments. In addition, the conduction-band offset (CBO) and valence-band offset (VBO) of InAsSbP/InAs HJs both present the upward bowing trend, with the CBO curves appearing sharp and the VBO curves appearing smooth.

  15. Comb-Net: a high-density WDM network with centralized wavelength combs

    NASA Astrophysics Data System (ADS)

    Gerla, Mario; Chiaretti, Guido; Rotolo, Salvatore

    1993-11-01

    In this paper, we propose Comb-Net, a tree PON architecture in which several laser combs at the root of the tree supply wavelengths to all stations in the PON. Namely, each station receives several wavelengths from comb laser sources located at the root of the PON, via a Comb Distribution network. It then selects (by fixed or tunable filters) some predefined or agreed upon wavelengths, and uses these as sources; i.e., it modulates them (in amplitude or phase) using an external modulator. The modulated wavelengths are then transmitted on the Multiaccess Communications network, which is separate from the Comb Distribution network. The novelty of Comb-Net is to replace the individual (fixed or tunable) lasers at the station with a set of centralized comb generators. The advantages are better stability control, lower noise and potentially lower cost since each station does not require a dedicated source. In the paper, we describe an example of Comb-Net architecture in which the Multiaccess Data network is based on a physical tree topology and on two separate virtual topologies embedded within the physical topology using WDM: a single hop topology used for circuit switched connections; and a multihop topology used for packet switched traffic. We illustrate the Comb-Net architecture with a simple case study.

  16. Frequency combs from crystalline resonators: influence of cavity parameters on comb dynamics

    NASA Astrophysics Data System (ADS)

    Grudinin, Ivan S.; Yu, Nan

    2014-12-01

    We experimentally study the factors that influence the span in frequency combs derived from the crystalline whispering gallery mode resonators. We observe that cavity dispersion plays an important role in generation of combs by a cascaded four-wave mixing process. We observed combs from the resonators with anomalous dispersion and nearly zero dispersion at the pump wavelength. In addition, the comb generation efficiency is found to be affected by the crossing of modes of different families. The influence of Raman gain is discussed as well as the roles of the cavity diameter and pump power.

  17. High Voltage Plane Cathode -Comb Anode Discharge

    NASA Astrophysics Data System (ADS)

    Mezei, P.

    1995-11-01

    Investigations on the characteristics of a plane cathode-comb anode discharge are presented. This discharge arrangement consists of a plane cathode with a series of anodes, resembling a comb, above it. A significant increase of the discharge voltage was obtained by increasing the number of comb-teeth. Voltage-current characteristics, the intensity and the spatial distribution of He, Al, and Ar spectral lines were investigated as functions of the number of comb-teeth, He pressure and discharge current. Due to the increase of discharge voltage, the spectral line intensities increased significantly in the negative glow region. In case of the Al-I 396.1 nm and the He-I 318.7 nm lines an intensity peak was observed also in the cathode glow region. This peak was pronounced in the case of high voltage anode arrangements and is attributed to excitation by positive ions.

  18. Frequency Comb Generation in Superconducting Resonators

    NASA Astrophysics Data System (ADS)

    Pappas, David; Erickson, Robert; Vissers, Michael; Ku, Hsiang-Sheng

    2015-03-01

    We have generated frequency combs spanning 0.5 to 20 GHz in superconducting λ = 2 resonators at T =3 K. Thin films of niobium-titanium nitride enabled this development due to their low loss, high nonlinearity, low frequency dispersion, and high critical temperature. The combs nucleate as sidebands around multiples of the pump frequency. Selection rules for the allowed frequency emission are calculated using perturbation theory, and the measured spectrum is shown to agree with the theory. Sideband spacing is measured to be accurate to 1 part in 108 The sidebands coalesce into a continuous comb structure observed to cover at least several frequency octaves. Generation of combs in this frequency range allows for unprecedented analysis of this non-linear phenomena in the time domain. We acknowledge DARPA and the NIST Quantum Information program.

  19. Wideband RF channelizer based on parametric combs

    NASA Astrophysics Data System (ADS)

    Zlatanovic, S.; Adleman, J. R.; Huynh, C. K.; Jester, S. B.; Lin, C.; Wiberg, A. O...; Myslivets, E.; Radic, S.; Jacobs, E. W.

    2015-05-01

    RF photonic channelizers can overcome limitations of conventional electronic methods for analysis of wideband RF spectral content. Here, we will present a recent progress on the RF photonic channelizer systems that are based on optical parametric combs. These systems can analyze very wide RF bandwidths exceeding 100GHz, therefore providing essential capability for the applications demanding a wide-bandwidth spectral analysis. The RF channelizers being presented utilize parametric processes in the highly non-linear fiber mixers to generate a large number of RF signal copies in the optical domain. Two different implementations for generation of RF signal copies will be presented and compared: one using a parametric multicasting and another utilizing a direct comb modulation. Generation of optical combs spanning more than 10THz will be shown. We will also present two distinct system architectures for RF photonic channelizer system: one employing a periodic optical filter such as Fabry-Perot etalon to select channels from the signal comb, and another one utilizing a coherent detection between a frequency-locked signal comb and a parametrically generated local oscillator (LO) comb. The second scheme gives benefit of providing both in-phase and quadrature (I/Q) information on channelized intermediate frequency (IF) signals. We will present a system with 32 implemented channels using a filtered scheme and a 32-channel coherent system with a full-field detection implemented on one tunable channel. Sensitivity and dynamic range as well as benefits of both system architectures will be discussed.

  20. Frequency comb transferred by surface plasmon resonance

    PubMed Central

    Geng, Xiao Tao; Chun, Byung Jae; Seo, Ji Hoon; Seo, Kwanyong; Yoon, Hana; Kim, Dong-Eon; Kim, Young-Jin; Kim, Seungchul

    2016-01-01

    Frequency combs, millions of narrow-linewidth optical modes referenced to an atomic clock, have shown remarkable potential in time/frequency metrology, atomic/molecular spectroscopy and precision LIDARs. Applications have extended to coherent nonlinear Raman spectroscopy of molecules and quantum metrology for entangled atomic qubits. Frequency combs will create novel possibilities in nano-photonics and plasmonics; however, its interrelation with surface plasmons is unexplored despite the important role that plasmonics plays in nonlinear spectroscopy and quantum optics through the manipulation of light on a subwavelength scale. Here, we demonstrate that a frequency comb can be transformed to a plasmonic comb in plasmonic nanostructures and reverted to the original frequency comb without noticeable degradation of <6.51 × 10−19 in absolute position, 2.92 × 10−19 in stability and 1 Hz in linewidth. The results indicate that the superior performance of a well-defined frequency comb can be applied to nanoplasmonic spectroscopy, quantum metrology and subwavelength photonic circuits. PMID:26898307

  1. Frequency comb transferred by surface plasmon resonance.

    PubMed

    Geng, Xiao Tao; Chun, Byung Jae; Seo, Ji Hoon; Seo, Kwanyong; Yoon, Hana; Kim, Dong-Eon; Kim, Young-Jin; Kim, Seungchul

    2016-01-01

    Frequency combs, millions of narrow-linewidth optical modes referenced to an atomic clock, have shown remarkable potential in time/frequency metrology, atomic/molecular spectroscopy and precision LIDARs. Applications have extended to coherent nonlinear Raman spectroscopy of molecules and quantum metrology for entangled atomic qubits. Frequency combs will create novel possibilities in nano-photonics and plasmonics; however, its interrelation with surface plasmons is unexplored despite the important role that plasmonics plays in nonlinear spectroscopy and quantum optics through the manipulation of light on a subwavelength scale. Here, we demonstrate that a frequency comb can be transformed to a plasmonic comb in plasmonic nanostructures and reverted to the original frequency comb without noticeable degradation of <6.51 × 10(-19) in absolute position, 2.92 × 10(-19) in stability and 1 Hz in linewidth. The results indicate that the superior performance of a well-defined frequency comb can be applied to nanoplasmonic spectroscopy, quantum metrology and subwavelength photonic circuits. PMID:26898307

  2. Frequency comb transferred by surface plasmon resonance

    NASA Astrophysics Data System (ADS)

    Geng, Xiao Tao; Chun, Byung Jae; Seo, Ji Hoon; Seo, Kwanyong; Yoon, Hana; Kim, Dong-Eon; Kim, Young-Jin; Kim, Seungchul

    2016-02-01

    Frequency combs, millions of narrow-linewidth optical modes referenced to an atomic clock, have shown remarkable potential in time/frequency metrology, atomic/molecular spectroscopy and precision LIDARs. Applications have extended to coherent nonlinear Raman spectroscopy of molecules and quantum metrology for entangled atomic qubits. Frequency combs will create novel possibilities in nano-photonics and plasmonics; however, its interrelation with surface plasmons is unexplored despite the important role that plasmonics plays in nonlinear spectroscopy and quantum optics through the manipulation of light on a subwavelength scale. Here, we demonstrate that a frequency comb can be transformed to a plasmonic comb in plasmonic nanostructures and reverted to the original frequency comb without noticeable degradation of <6.51 × 10-19 in absolute position, 2.92 × 10-19 in stability and 1 Hz in linewidth. The results indicate that the superior performance of a well-defined frequency comb can be applied to nanoplasmonic spectroscopy, quantum metrology and subwavelength photonic circuits.

  3. Frequency Comb Velocity Modulation Spectroscopy

    NASA Astrophysics Data System (ADS)

    Cossel, Kevin C.; Sinclair, Laura C.; Coffey, Tyler; Cornell, Eric; Ye, Jun

    2011-06-01

    We have developed a novel technique for rapid ion-sensitive spectroscopy over a broad spectral bandwidth by combining the high sensitivity of velocity modulation spectroscopy (VMS) with the parallel nature and high frequency accuracy of cavity-enhanced direct frequency comb spectroscopy. Prior to this research, no techniques have been capable of high sensitivity velocity modulation spectroscopy on every parallel detection channel over such a broad spectral range. We have demonstrated the power of this technique by measuring the A^2?_u - X^2?_g^+ (4,2) band of N_2^+ at 830 nm with an absorption sensitivity of 110-6 for each of 1500 simultaneous measurement channels spanning 150 Cm-1. A densely sampled spectrum consisting of interleaved measurements to achieve 75 MHz spacing is acquired in under an hour. This technique is ideally suited for high resolution survey spectroscopy of molecular ions with applications including chemical physics, astrochemistry, and precision measurement. Currently, this system is being used to map the electronic transitions of HfF^+ for the JILA electron electric dipole moment (eEDM) experiment. The JILA eEDM experiment uses trapped molecular ions to significantly increase the coherence time of the measurement in addition to utilizing the strong electric field enhancement available from molecules. Previous theoretical work has shown that the metastable ^3?_1 state in HfF^+ and ThF^+ provides high sensitivity to the eEDM and good cancellation of systematic effects; however, the electronic level structure of these species have not previously been measured, and the theoretical uncertainties are hundreds to thousands of wavenumbers. This necessitates broad-bandwidth, high-resolution survey spectroscopy provided by frequency comb VMS in the 700-900 nm spectral window. F. Adler, M. J. Thorpe, K. C. Cossel, and J. Ye. Annu. Rev. Anal. Chem. 3, 175-205 (2010) A. E. Leanhardt, et. al. arXiv:1008.2997v2 E. Meyer, J. L. Bohn, and M. P. Deskevich. Phys. Rev. A 73, 062108 (2006) A. N. Petrov, N. S. Mosyagin, T. A. Isaev, and A. V. Titov Phys. Rev. A 76, 030501 (2007)

  4. George Combe and common sense.

    PubMed

    Dyde, Sean

    2015-06-01

    This article examines the history of two fields of enquiry in late eighteenth- and early nineteenth-century Scotland: the rise and fall of the common sense school of philosophy and phrenology as presented in the works of George Combe. Although many previous historians have construed these histories as separate, indeed sometimes incommensurate, I propose that their paths were intertwined to a greater extent than has previously been given credit. The philosophy of common sense was a response to problems raised by Enlightenment thinkers, particularly David Hume, and spurred a theory of the mind and its mode of study. In order to succeed, or even to be considered a rival of these established understandings, phrenologists adapted their arguments for the sake of engaging in philosophical dispute. I argue that this debate contributed to the relative success of these groups: phrenology as a well-known historical subject, common sense now largely forgotten. Moreover, this history seeks to question the place of phrenology within the sciences of mind in nineteenth-century Britain. PMID:25921681

  5. Laboratory duplication of comb layering in the Rhum pluton. [igneous rocks with comb layered texture

    NASA Technical Reports Server (NTRS)

    Donaldson, C. H.

    1977-01-01

    A description is provided of the texture of harrisite comb layers, taking into account the results of crystallization experiments at controlled cooling rates, which have reproduced the textural change from 'cumulate' to comb-layered harrisite. Melted samples of harrisite were used in the dynamic crystallization experiments considered. The differentiation of a cooling rate run with respect to olivine grain size and shape is shown and three possible origins of hopper olivine in differentiated crystallization runs are considered. It is found that olivine nucleation occurred throughout cooling, except for the incubation period during early cooling. The elongate combed olivines in harrisite apparently grew as the magma locally supercooled to at least 30 C. It is suggested that the branching crystals in most comb layers, including comb-layered harrisite, probably grew along thermal gradients.

  6. Electrostatic comb drive for vertical actuation

    SciTech Connect

    Lee, A. P., LLNL

    1997-07-10

    The electrostatic comb finger drive has become an integral design for microsensor and microactuator applications. This paper reports on utilizing the levitation effect of comb fingers to design vertical-to-the-substrate actuation for interferometric applications. For typical polysilicon comb drives with 2 {micro}m gaps between the stationary and moving fingers, as well as between the microstructures and the substrate, the equilibrium position is nominally 1-2 {micro}m above the stationary comb fingers. This distance is ideal for many phase shifting interferometric applications. Theoretical calculations of the vertical actuation characteristics are compared with the experimental results, and a general design guideline is derived from these results. The suspension flexure stiffnesses, gravity forces, squeeze film damping, and comb finger thicknesses are parameters investigated which affect the displacement curve of the vertical microactuator. By designing a parallel plate capacitor between the suspended mass and the substrate, in situ position sensing can be used to control the vertical movement, providing a total feedback-controlled system. Fundamentals of various capacitive position sensing techniques are discussed. Experimental verification is carried out by a Zygo distance measurement interferometer.

  7. Radiation comb generation with extended Josephson junctions

    NASA Astrophysics Data System (ADS)

    Solinas, P.; Bosisio, R.; Giazotto, F.

    2015-09-01

    We propose the implementation of a Josephson radiation comb generator based on an extended Josephson junction subject to a time dependent magnetic field. The junction critical current shows known diffraction patterns and determines the position of the critical nodes when it vanishes. When the magnetic flux passes through one of such critical nodes, the superconducting phase must undergo a ?-jump to minimize the Josephson energy. Correspondingly, a voltage pulse is generated at the extremes of the junction. Under periodic driving, this allows us to produce a comb-like voltage pulses sequence. In the frequency domain, it is possible to generate up to hundreds of harmonics of the fundamental driving frequency, thus mimicking the frequency comb used in optics and metrology. We discuss several implementations through a rectangular, cylindrical, and annular junction geometries, allowing us to generate different radiation spectra and to produce an output power up to 10 pW at 50 GHz for a driving frequency of 100 MHz.

  8. Microresonator-based optical frequency combs.

    PubMed

    Kippenberg, T J; Holzwarth, R; Diddams, S A

    2011-04-29

    The series of precisely spaced, sharp spectral lines that form an optical frequency comb is enabling unprecedented measurement capabilities and new applications in a wide range of topics that include precision spectroscopy, atomic clocks, ultracold gases, and molecular fingerprinting. A new optical frequency comb generation principle has emerged that uses parametric frequency conversion in high resonance quality factor (Q) microresonators. This approach provides access to high repetition rates in the range of 10 to 1000 gigahertz through compact, chip-scale integration, permitting an increased number of comb applications, such as in astronomy, microwave photonics, or telecommunications. We review this emerging area and discuss opportunities that it presents for novel technologies as well as for fundamental science. PMID:21527707

  9. Sharpening technique to decrease comb passband deviation

    NASA Astrophysics Data System (ADS)

    Jovanovic Dolecek, Gordana

    2015-01-01

    The decimation filter is necessary to prevent aliasing during the process of decreasing sampling rate, which is called decimation. Due its simplicity, the most popular decimation filter is the comb filter. However, this filter exhibits a high passband droop in the passband magnitude characteristic, which must be avoided to prevent the distortion of the decimated signal. In this paper we present the sharpening technique to improve comb passband characteristic. In order to decrease complexity introduced by sharpening, we also consider two-stage structure where the sharpening is applied only at the second stage. Different examples are included to illustrate the benefits of the proposed method.

  10. Dual-comb spectroscopy based on quantum-cascade-laser frequency combs.

    PubMed

    Villares, Gustavo; Hugi, Andreas; Blaser, Stéphane; Faist, Jérôme

    2014-01-01

    Dual-comb spectroscopy performed in the mid-infrared-where molecules have their strongest rotovibrational absorption lines-offers the promise of high spectral resolution broadband spectroscopy with very short acquisition times (μs) and no moving parts. Recently, we demonstrated frequency comb operation of a quantum-cascade-laser. We now use that device in a compact, dual-comb spectrometer. The noise properties of the heterodyne beat are close to the shot noise limit. Broadband (15 cm(-1)) high-resolution (80 MHz) absorption spectroscopy of both a GaAs etalon and water vapour is demonstrated, showing the potential of quantum-cascade-laser frequency combs as the basis for a compact, all solid-state, broadband chemical sensor. PMID:25307936

  11. Time sequence photography of Roosters Comb

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The importance of understanding natural landscape changes is key in properly determining rangeland ecology. Time sequence photography allows a landscape snapshot to be documented and enables the ability to compare natural changes overtime. Photographs of Roosters Comb were taken from the same vantag...

  12. Phase separation of comb polymer nanocomposite melts.

    PubMed

    Xu, Qinzhi; Feng, Yancong; Chen, Lan

    2016-02-01

    In this work, the spinodal phase demixing of branched comb polymer nanocomposite (PNC) melts is systematically investigated using the polymer reference interaction site model (PRISM) theory. To verify the reliability of the present method in characterizing the phase behavior of comb PNCs, the intermolecular correlation functions of the system for nonzero particle volume fractions are compared with our molecular dynamics simulation data. After verifying the model and discussing the structure of the comb PNCs in the dilute nanoparticle limit, the interference among the side chain number, side chain length, nanoparticle-monomer size ratio and attractive interactions between the comb polymer and nanoparticles in spinodal demixing curves is analyzed and discussed in detail. The results predict two kinds of distinct phase separation behaviors. One is called classic fluid phase boundary, which is mediated by the entropic depletion attraction and contact aggregation of nanoparticles at relatively low nanoparticle-monomer attraction strength. The second demixing transition occurs at relatively high attraction strength and involves the formation of an equilibrium physical network phase with local bridging of nanoparticles. The phase boundaries are found to be sensitive to the side chain number, side chain length, nanoparticle-monomer size ratio and attractive interactions. As the side chain length is fixed, the side chain number has a large effect on the phase behavior of comb PNCs; with increasing side chain number, the miscibility window first widens and then shrinks. When the side chain number is lower than a threshold value, the phase boundaries undergo a process from enlarging the miscibility window to narrowing as side chain length increases. Once the side chain number overtakes this threshold value, the phase boundary shifts towards less miscibility. With increasing nanoparticle-monomer size ratio, a crossover of particle size occurs, above which the phase separation is consistent with that of chain PNCs. The miscibility window for this condition gradually narrows while the other parameters of the PNCs system are held constant. These results indicate that the present PRISM theory can give molecular-level details of the underlying mechanisms of the comb PNCs. It is hoped that the results can be used to provide useful guidance for the future design control of novel, thermodynamically stable comb PNCs. PMID:26754414

  13. 40 nm wavelength tunable gain-switched optical comb source.

    PubMed

    Zhou, Rui; Latkowski, Sylwester; O'Carroll, John; Phelan, Richard; Barry, Liam P; Anandarajah, Prince

    2011-12-12

    A wavelength tunable optical comb is generated based on the gain-switching of an externally seeded Fabry-Pérot laser diode. The comb consists of about eight clearly resolved 10 GHz coherent sidebands within 3 dB spectral envelope peak and is tunable over the entire C-band (1530 to 1570 nm). The optical linewidth of the individual comb tones is measured to be lower than 100 kHz, and the RIN of the individually filtered comb tones (<-120 dB/Hz) is shown to be comparable to the entire unfiltered comb (<-135 dB/Hz). Besides, expansion of the tunable gain switched comb is achieved with the aid of an optical phase modulator, resulting in near doubling of the number of comb tones. PMID:22274051

  14. Injection locking of Yb-fiber based optical frequency comb.

    PubMed

    Kuse, Naoya; Ozawa, Akira; Nomura, Yutaka; Ito, Isao; Kobayashi, Yohei

    2012-05-01

    We demonstrated the synchronization of offset and repetition frequency between two independent Yb-doped fiber mode-locked lasers by injection locking. By injecting master-laser pulse-train into slave laser cavity, stability and accuracy of master frequency comb are transferred to slave comb. Passive stabilization of frequency comb offers robust and convenient way to duplicate frequency comb that can be applied to long-distance comb transfer. Injecting master pulse would also help to initiate and stabilize mode-locking of high repetition rate or ultrabroadband frequency combs. Additionally, we also demonstrated even more robust synchronization of combs can be achieved with the help of active stabilization of relative offset frequency difference. PMID:22565676

  15. The Rose-comb Mutation in Chickens Constitutes a Structural Rearrangement Causing Both Altered Comb Morphology and Defective Sperm Motility

    PubMed Central

    Boije, Henrik; Bed'hom, Bertrand; Fillon, Valérie; Dorshorst, Ben; Rubin, Carl-Johan; Liu, Ranran; Gao, Yu; Gu, Xiaorong; Wang, Yanqiang; Gourichon, David; Zody, Michael C.; Zecchin, William; Vieaud, Agathe; Tixier-Boichard, Michèle; Hu, Xiaoxiang; Hallböök, Finn; Li, Ning; Andersson, Leif

    2012-01-01

    Rose-comb, a classical monogenic trait of chickens, is characterized by a drastically altered comb morphology compared to the single-combed wild-type. Here we show that Rose-comb is caused by a 7.4 Mb inversion on chromosome 7 and that a second Rose-comb allele arose by unequal crossing over between a Rose-comb and wild-type chromosome. The comb phenotype is caused by the relocalization of the MNR2 homeodomain protein gene leading to transient ectopic expression of MNR2 during comb development. We also provide a molecular explanation for the first example of epistatic interaction reported by Bateson and Punnett 104 years ago, namely that walnut-comb is caused by the combined effects of the Rose-comb and Pea-comb alleles. Transient ectopic expression of MNR2 and SOX5 (causing the Pea-comb phenotype) occurs in the same population of mesenchymal cells and with at least partially overlapping expression in individual cells in the comb primordium. Rose-comb has pleiotropic effects, as homozygosity in males has been associated with poor sperm motility. We postulate that this is caused by the disruption of the CCDC108 gene located at one of the inversion breakpoints. CCDC108 is a poorly characterized protein, but it contains a MSP (major sperm protein) domain and is expressed in testis. The study illustrates several characteristic features of the genetic diversity present in domestic animals, including the evolution of alleles by two or more consecutive mutations and the fact that structural changes have contributed to fast phenotypic evolution. PMID:22761584

  16. Mesoscopic description of random walks on combs

    NASA Astrophysics Data System (ADS)

    Méndez, Vicenç; Iomin, Alexander; Campos, Daniel; Horsthemke, Werner

    2015-12-01

    Combs are a simple caricature of various types of natural branched structures, which belong to the category of loopless graphs and consist of a backbone and branches. We study continuous time random walks on combs and present a generic method to obtain their transport properties. The random walk along the branches may be biased, and we account for the effect of the branches by renormalizing the waiting time probability distribution function for the motion along the backbone. We analyze the overall diffusion properties along the backbone and find normal diffusion, anomalous diffusion, and stochastic localization (diffusion failure), respectively, depending on the characteristics of the continuous time random walk along the branches, and compare our analytical results with stochastic simulations.

  17. Laser Frequency Combs for Astronomical Observations

    NASA Astrophysics Data System (ADS)

    Steinmetz, Tilo; Wilken, Tobias; Araujo-Hauck, Constanza; Holzwarth, Ronald; Hnsch, Theodor W.; Pasquini, Luca; Manescau, Antonio; D'Odorico, Sandro; Murphy, Michael T.; Kentischer, Thomas; Schmidt, Wolfgang; Udem, Thomas

    2008-09-01

    A direct measurement of the universes expansion history could be made by observing in real time the evolution of the cosmological redshift of distant objects. However, this would require measurements of Doppler velocity drifts of ~1 centimeter per second per year, and astronomical spectrographs have not yet been calibrated to this tolerance. We demonstrated the first use of a laser frequency comb for wavelength calibration of an astronomical telescope. Even with a simple analysis, absolute calibration is achieved with an equivalent Doppler precision of ~9 meters per second at ~1.5 micrometersbeyond state-of-the-art accuracy. We show that tracking complex, time-varying systematic effects in the spectrograph and detector system is a particular advantage of laser frequency comb calibration. This technique promises an effective means for modeling and removal of such systematic effects to the accuracy required by future experiments to see direct evidence of the universes putative acceleration.

  18. Frequency-agile dual-comb spectroscopy

    NASA Astrophysics Data System (ADS)

    Millot, Guy; Pitois, Stéphane; Yan, Ming; Hovhannisyan, Tatevik; Bendahmane, Abdelkrim; Hänsch, Theodor W.; Picqué, Nathalie

    2016-01-01

    Spectroscopic gas sensing and its applications to, for example, trace detection or chemical kinetics, require ever more demanding measurement times, acquisition rates, sensitivities, precisions and broad tuning ranges. Here, we propose a new approach to near-infrared molecular spectroscopy, utilizing advanced concepts of optical telecommunications and supercontinuum photonics. We generate, without mode-locked lasers, two frequency combs of slightly different repetition frequencies and moderate, but rapidly tunable, spectral span. The output of a frequency-agile continuous-wave laser is split and sent into two electro-optic intensity modulators. Flat-top low-noise frequency combs are produced by wave-breaking in a nonlinear optical fibre of normal dispersion. With a dual-comb spectrometer, we record Doppler-limited spectra spanning 60 GHz within 13 μs and an 80 kHz refresh rate, at a tuning speed of 10 nm s-1. The sensitivity for weak absorption is enhanced by a long gas-filled hollow-core fibre. New opportunities for real-time diagnostics may be opened up, even outside the laboratory.

  19. Outbreak of comb necrosis in layer breeder chickens.

    PubMed

    Nakamura, K; Shirai, J; Imai, K; Hihara, H; Tanimura, N

    1997-01-01

    Comb necrosis with leg weakness was seen in 41-day-old female layer breeder chickens. This disease occurred in three flocks at a breeder farm, but not in other flocks of growing chickens and broiler breeder hens at the same farm. The disease started in 35-day-old chicks in three flocks. The morbidity of comb necrosis was 10% and that of leg weakness was 3%. Characteristic gross lesions of affected chickens were swelling and necrosis of the whole comb. Histologically, liquefactive necrosis of epidermal epithelial cells with hyperplasia, vesicle formation in the epidermis, congestion, and hemorrhages with fibrinous thrombi of underlying dermis in the comb were noted. In mature comb lesions, the epidermis showed eosinophilic necrosis (scab formation). In the livers, multiple fibrinous thrombi were present in the sinusoids and there was necrosis of hepatic cells. Staphylococcus aureus and Pasturella spp. were isolated from comb lesions. There were no significant lesions causing leg weakness. PMID:9087344

  20. Recent advances in ultrafast optical parametric oscillator frequency combs

    NASA Astrophysics Data System (ADS)

    McCracken, Richard A.; Zhang, Zhaowei; Reid, Derryck T.

    2014-12-01

    We discuss recent advances in the stabilization and application of femtosecond frequency combs based on optical parametric oscillators (OPOs) pumped by femtosecond lasers at 800 and 1060 nm. A method for locking to zero the carrier-envelope-offset of a Ti:sapphire-pumped OPO comb is described. The application of Yb:KYW-laser-pumped dual-combs for mid-infrared spectroscopy is detailed, specifically methane spectroscopy at approximately a 0.7% concentration at 1 atm.

  1. Endless frequency shifting of optical frequency comb lines.

    PubMed

    Benkler, Erik; Rohde, Felix; Telle, Harald R

    2013-03-11

    The functional principle of a novel technique for frequency shifting lines of an optical frequency comb is demonstrated. The underlying principle is to shift the carrier frequency by changing the carrier phase within the time span between subsequent pulses of a mode-locked laser used as comb generator. This universal frequency shifter does not require intrusion into the comb generator and provides high agility for arbitrary temporal frequency evolutions. PMID:23482149

  2. High-Temperature Thermoelectric Properties of the Solid–Solution Zintl Phase Eu11Cd6Sb12–xAsx (x < 3)

    SciTech Connect

    Kazem, Nasrin; Xie, Weiwei; Ohno, Saneyuki; Zevalkink, Alexandra; Miller, Gordon J; Snyder, G Jeffrey; Kauzlarich, Susan M

    2014-02-11

    Zintl phases are compounds that have shown promise for thermoelectric applications. The title solid–solution Zintl compounds were prepared from the elements as single crystals using a tin flux for compositions x = 0, 1, 2, and 3. Eu11Cd6Sb12–xAsx (x < 3) crystallize isostructurally in the centrosymmetric monoclinic space group C2/m (no. 12, Z = 2) as the Sr11Cd6Sb12 structure type (Pearson symbol mC58). Efforts to make the As compositions for x exceeding ~3 resulted in structures other than the Sr11Cd6Sb12 structure type. Single-crystal X-ray diffraction indicates that As does not randomly substitute for Sb in the structure but is site specific for each composition. The amount of As determined by structural refinement was verified by electron microprobe analysis. Electronic structures and energies calculated for various model structures of Eu11Cd6Sb10As2 (x = 2) indicated that the preferred As substitution pattern involves a mixture of three of the six pnicogen sites in the asymmetric unit. In addition, As substitution at the Pn4 site opens an energy gap at the Fermi level, whereas substitution at the other five pnicogen sites remains semimetallic with a pseudo gap. Thermoelectric properties of these compounds were measured on hot-pressed, fully densified pellets. Samples show exceptionally low lattice thermal conductivities from room temperature to 775 K: 0.78–0.49 W/mK for x = 0; 0.72–0.53 W/mK for x = 1; and 0.70–0.56 W/mK for x = 2. Eu11Cd6Sb12 shows a high p-type Seebeck coefficient (from +118 to 153 μ V/K) but also high electrical resistivity (6.8 to 12.8 mΩ·cm). The value of zT reaches 0.23 at 774 K. The properties of Eu11Cd6Sb12–xAsx are interpreted in discussion with the As site substitution.

  3. Frequency comb from a microresonator with engineered spectrum.

    PubMed

    Grudinin, Ivan S; Baumgartel, Lukas; Yu, Nan

    2012-03-12

    We demonstrate that by varying the ratio between the linewidth and dispersion of a whispering gallery mode resonator we are able to control the number N of free spectral ranges separating the first generated comb sidebands from the pump. We observed combs with N = 19 and N = 1. For the comb with N = 1 we have achieved a span of over 200 nm using a 0.4 mm MgF? resonator pumped with 50 mW at 1560 nm. This pump power is a factor of 10 lower than previously reported for combs with comparable bandwidth. PMID:22418543

  4. Optimization of filtering schemes for broadband astro-combs.

    PubMed

    Chang, Guoqing; Li, Chih-Hao; Phillips, David F; Szentgyorgyi, Andrew; Walsworth, Ronald L; Krtner, Franz X

    2012-10-22

    To realize a broadband, large-line-spacing astro-comb, suitable for wavelength calibration of astrophysical spectrographs, from a narrowband, femtosecond laser frequency comb ("source-comb"), one must integrate the source-comb with three additional components: (1) one or more filter cavities to multiply the source-comb's repetition rate and thus line spacing; (2) power amplifiers to boost the power of pulses from the filtered comb; and (3) highly nonlinear optical fiber to spectrally broaden the filtered and amplified narrowband frequency comb. In this paper we analyze the interplay of Fabry-Perot (FP) filter cavities with power amplifiers and nonlinear broadening fiber in the design of astro-combs optimized for radial-velocity (RV) calibration accuracy. We present analytic and numeric models and use them to evaluate a variety of FP filtering schemes (labeled as identical, co-prime, fraction-prime, and conjugate cavities), coupled to chirped-pulse amplification (CPA). We find that even a small nonlinear phase can reduce suppression of filtered comb lines, and increase RV error for spectrograph calibration. In general, filtering with two cavities prior to the CPA fiber amplifier outperforms an amplifier placed between the two cavities. In particular, filtering with conjugate cavities is able to provide <1 cm/s RV calibration error with >300 nm wavelength coverage. Such superior performance will facilitate the search for and characterization of Earth-like exoplanets, which requires <10 cm/s RV calibration error. PMID:23187265

  5. Generation of 2 THz Span Optical Comb in a Tunable Fiber Ring Based Optical Frequency Comb Generator

    NASA Astrophysics Data System (ADS)

    Shen, P.; Gomes, N. J.; Davies, P. A.; Shillue, W. P.

    2007-10-01

    The generation of a 2 THz span optical comb, defined within a 10 dB power envelope and consisting of 200 optical comb lines, all stronger than -20 dBm without amplification, is reported. The effective transmittance of the generator is 11.5 dB. The comb line spacing can be adjusted with a step frequency that equals an integer multiple of 12.500 MHz while maintaining the comb profile. High coherence between the comb lines is achieved, with the bent signal between the comb lines having a noise level of -92 dBc/Hz at 1 kHz offset, and phase noise of -130 dBc/Hz at 1 MHz offset.

  6. Dual-comb spectroscopy with a phase-modulated probe comb for sub-MHz spectral sampling.

    PubMed

    Hébert, Nicolas Bourbeau; Michaud-Belleau, Vincent; Magnan-Saucier, Sébastien; Deschênes, Jean-Daniel; Genest, Jérôme

    2016-05-15

    We present a straightforward and efficient method to reduce the mode spacing of a frequency comb based on binary pseudo-random phase modulation of its pulse train. As a proof of concept, we use such a densified comb to perform dual-comb spectroscopy of a long-delay Mach-Zehnder interferometer and a high-quality-factor microresonator with sub-MHz spectral sampling. Since this approach is based on binary phase modulation, it combines all the advantages of other densification techniques: simplicity, single-step implementation, and conservation of the initial comb's power. PMID:27176983

  7. Integrated Photonic Comb Generation: Applications in Coherent Communication and Sensing

    NASA Astrophysics Data System (ADS)

    Parker, John S.

    Integrated photonics combines many optical components including lasers, modulators, waveguides, and detectors in close proximity via homogeneous (monolithic) or heterogeneous (using multiple materials) integration. This improves stability for interferometers and lasers, reduces the occurrence of unwanted reflections, and it avoids coupling losses between different components as they are on the same chip. Thus, less power is needed to compensate for these added losses, and less heat needs to be removed due to these power savings. In addition, integration allows the many components that comprise a system to be fabricated together, thereby reducing the cost per system and allowing rapid scaling in production throughput. Integrated optical combs have many applications including: metrology, THz frequency generation, arbitrary waveform generation, optical clocks, photonic analog-to-digital converters, sensing (imaging), spectroscopy, and data communication. A comb is a set of optical sources evenly spaced in frequency. Several methods of comb generation including mode-locking and optical parametric oscillation produce phase-matched optical outputs with a fixed phase relationship between the frequency lines. When the absolute frequency of a single comb line is stabilized along with the frequency spacing between comb lines, absolute phase and frequency precision can be achieved over the entire comb bandwidth. This functionality provides tremendous benefits to many applications such as coherent communication and optical sensing. The goals for this work were achieving a broad comb bandwidth and noise reduction, i.e., frequency and phase stability. Integrated mode-locked lasers on the InGaAsP/InP material platform were chosen, as they could be monolithically integrated with the wide range of highly functional and versatile photonic integrated circuits (PICs) previously demonstrated on this platform at UCSB. Gain flattening filters were implemented to increase the comb bandwidths to 2.5 THz. Active mode-locking with an RF source was used to precisely set the frequency spacing between comb lines with better than 10 Hz accuracy. An integrated optical phase-locked loop (OPLL) for the comb was designed, built, and tested. The OPLL fixed a single comb line to a stable single linewidth laser, demonstrating a ˜430 Hz FWHM optical linewidth on the locked comb line and 20º RMS phase deviation between the comb and optical reference. The free-running linewidth is 50--100 MHz, demonstrating over 50 dB improvement in optical linewidth via locking. An integrated tunable laser (SG-DBR) with an OPLL was phase-locked to a comb source with a fixed offset frequency, thus showing the potential for using a comb with SG-DBRs as a compact frequency synthesizer.

  8. High temperature and composition induced phase transitions in LiZnV?-xAsxO? phenacites: Crystal structure and Raman spectroscopy studies.

    PubMed

    Manoun, B; Azrour, M; Lazor, P; Azdouz, M; Bih, L; Benmokhtar, S; Essehli, R; El Ammari, L

    2015-12-01

    In this work, using techniques of X-ray diffraction and Raman spectroscopy, we report the composition and high-temperature induced phase transition in the system LiZnV1-xAsxO4 (0?x?1). Both techniques showed that the increase of arsenic amount induced a structural transition from R-3 LiZnVO4 type to LiZnAsO4 type belonging to R3 space group, the transition occurring between x=0.7 and x=0.8. Furthermore, increasing temperature for the compositions (0.8?x?1) manifests a transition from the LiZnAsO4 structural type with R3 space group to the R-3 LiZnVO4 structural type. For this series, the transition from the space group R3 to the centro-symmetric space group R-3 shows considerable changes in the compositional and temperature dependencies of the bands: spectral positions of all the observed Raman bands exhibit shifts linearly proportional to the temperature increase, with points of shift-rate changes revealing a symmetry change. The Raman-spectra based temperature-composition phase diagram confirms the results obtained using the method of Rietveld refinements, thus showing the R-3 to R3 transition occurring between x=0.7 and 0.8. PMID:26186614

  9. Spectrally interleaved, comb-mode-resolved spectroscopy using swept dual terahertz combs

    PubMed Central

    Hsieh, Yi-Da; Iyonaga, Yuki; Sakaguchi, Yoshiyuki; Yokoyama, Shuko; Inaba, Hajime; Minoshima, Kaoru; Hindle, Francis; Araki, Tsutomu; Yasui, Takeshi

    2014-01-01

    Optical frequency combs are innovative tools for broadband spectroscopy because a series of comb modes can serve as frequency markers that are traceable to a microwave frequency standard. However, a mode distribution that is too discrete limits the spectral sampling interval to the mode frequency spacing even though individual mode linewidth is sufficiently narrow. Here, using a combination of a spectral interleaving and dual-comb spectroscopy in the terahertz (THz) region, we achieved a spectral sampling interval equal to the mode linewidth rather than the mode spacing. The spectrally interleaved THz comb was realized by sweeping the laser repetition frequency and interleaving additional frequency marks. In low-pressure gas spectroscopy, we achieved an improved spectral sampling density of 2.5 MHz and enhanced spectral accuracy of 8.39 × 10−7 in the THz region. The proposed method is a powerful tool for simultaneously achieving high resolution, high accuracy, and broad spectral coverage in THz spectroscopy. PMID:24448604

  10. Efficiency optimization for atomic frequency comb storage

    SciTech Connect

    Bonarota, M.; Ruggiero, J.; Le Goueet, J.-L.; Chaneliere, T.

    2010-03-15

    We study the efficiency of the atomic frequency comb storage protocol. We show that for a given optical depth, the preparation procedure can be optimize to significantly improve the retrieval. Our prediction is well supported by the experimental implementation of the protocol in a Tm{sup 3+}:YAG crystal. We observe a net gain in efficiency from 10 to 17% by applying the optimized preparation procedure. In the perspective of high bandwidth storage, we investigate the protocol under different magnetic fields. We analyze the effect of the Zeeman and superhyperfine interaction.

  11. Superdiffusion of cancer on a comb structure

    NASA Astrophysics Data System (ADS)

    Iomin, Alexander

    2005-01-01

    The influence of cell fission on transport properties of the vessel network is studied. A simple mathematical model is proposed by virtue of heuristic arguments on tumor development. The constructed model is a modification of a so-called comb structure. In the framework of this model we are able to show that the tumor development corresponds to fractional transport of cells. A possible answer to the question how the malignant neoplasm cells appear at an arbitrary distance from the primary tumor is proposed. The model could also be a possible mechanism for diffusive cancers.

  12. Dual-Comb Spectroscopy in the Open Air

    NASA Astrophysics Data System (ADS)

    Rieker, Greg B.; Klose, Andrew; Diddams, Scott; Coddington, Ian; Giorgetta, Fabrizio; Sinclair, Laura; Baumann, Esther; Truong, Gar-Wing; Ycas, Gabriel; Swann, William C.; Newbury, Nathan R.

    2015-06-01

    Dual-comb spectroscopy is arguably the natural successor to FTIR. Based on the interference between two frequency combs, this technique can record broadband spectra with a resolution better than 0.0003 wn. Like FTIR, dual-comb spectroscopy measures an entire spectrum simultaneously, allowing for suppression of systematic errors related to temporal dynamics of the sample. Unlike FTIR it records the entire spectrum with virtually no instrument lineshape or error in the frequency axis. The lack of moving parts in dual-comb spectroscopy means that spectra can be recorded in milliseconds to microseconds with the desired signal-to-noise being the only real constrain on the minimum recording time. Finally the high spacial beam quality of the frequency combs allows for increased sensitivity through long interaction paths either in free-space, multi-pass cells or enhancement cavities. This talk will explore the recent use of dual-comb spectroscopy in the near-infrared to measure atmospheric carbon dioxide, methane and water concentrations over a 2-km outdoor open-air path. Due to many of the strengths just mentioned, precisions of <1 ppm for CO_2 and <3 ppb for CH_4 in 5 min are achieved making this system very attractive for carbon monitoring at length scales relevant to carbon transport models. Additionally this presentation will address recent work on robust, compact, and portable dual-comb spectrometers as well as dual-comb spectroscopy further into the IR.

  13. Coherent Raman dual-comb spectroscopy and imaging

    NASA Astrophysics Data System (ADS)

    Ideguchi, Takuro; Holzner, Simon; Bernhardt, Birgitta; Guelachvili, Guy; Hänsch, Theodor W.; Picqué, Nathalie

    2014-11-01

    The invention of the optical frequency comb technique has revolutionized the field of precision spectroscopy, providing a way to measure the absolute frequency of any optical transition. Since, frequency combs have become common equipment for frequency metrology. In the last decade, novel applications for the optical frequency comb have been demonstrated beyond its original purpose. Broadband molecular spectroscopy is one of those. One such technique of molecular spectroscopy with frequency combs, dual-comb Fourier transform spectroscopy provides short measurement times with resolution and accuracy. Two laser frequency combs with slightly different repetition frequencies generate pairs of pulses with a linearly-scanned delay between pulses in a pair. The system without moving parts mimics a fast scanning Fourier transform interferometer. The measurement speed may be several orders of magnitude faster than that of a Michelson-based Fourier transform spectrometer, which opens up new opportunities for broadband molecular spectroscopy. Recently, dual-comb spectroscopy has been extended to nonlinear phenomena. A broadband Raman spectrum of molecular fingerprints may be measured within a few tens of microseconds with coherent Raman dual-comb spectroscopy. Raster scanning the sample leads to hyperspectral images. This rapid and broadband label-free vibrational spectroscopy and imaging technique might provide new diagnostic methods in a variety of scientific and industrial fields.

  14. Does combing the scalp reduce scalp electrode impedances?

    PubMed

    Mahajan, Yatin; McArthur, Genevieve

    2010-05-15

    Electrical activity from the human brain can be recorded via electrodes on the scalp. It is important to reduce the impedance of each electrode to minimize unwanted noise in the recording. Electrode impedance can be improved by abrading the skin to remove dead skin cells. In this experiment, we tested if abrading the skin by combing the scalp leads to a significant reduction in electrode impedance. We compared the mean electrode impedance values of 20 subjects whose scalps were combed prior to electrode cap placement, with 20 subjects whose scalps were not combed. Combing significantly reduced the impedances at central, right, and left areas of the scalp. This finding supports the use of scalp combing to reduce the time and subject discomfort that can be associated with placing scalp electrodes. This is particularly important for experiments testing children. PMID:20211649

  15. Theory and applications of sampled analog recursive CTD comb filters

    NASA Technical Reports Server (NTRS)

    Tao, T. F.; Holmes, S. V.; Ejaz, A.; Piazza, F.; Saetre, L. T.; Freund, B.

    1976-01-01

    Sampled analog comb filter using a recursive filter implementation was studied. Charge transfer device delay lines were used as the delay elements. The similarities and differences between sampled analog recursive filter and digital recursive filter were pointed out. Both canceller type and integrator type comb filter using the first order or the second order canonical circuits were studied. Experimental results of frequency response are presented to show their difference from that of digital filters. A theoretical analysis was presented based essentially on the digital filter theory but modified to take into account the differences described above. The usefulness of this theory in analyzing the comb filter characteristics was discussed. Several applications of both the canceller type comb filter and the integrator type comb filter were demonstrated.

  16. Optical study of narrow band gap InAsxSb1 -x (x =0 , 0.25, 0.5, 0.75, 1) alloys

    NASA Astrophysics Data System (ADS)

    Namjoo, Shirin; Rozatian, Amir S. H.; Jabbari, Iraj; Puschnig, Peter

    2015-05-01

    The structural, electronic, and optical properties of InAs, InSb, and their ternary alloys InAsxSb1 -x (x =0.25 , 0.5, 0.75) are investigated within density functional theory utilizing the wien2k package. We find that the lattice constants and bulk moduli as a function of x are in best agreement with Vegard's linear rule. When computing the electronic band structures with the modified Becke-Johnson exchange-correlation functional (mBJLDA), our results for the band gaps of InAs, InSb, and their ternary alloys are in good agreement with the available experimental results while the conventional Wu-Cohen generalized gradient approximation (GGA) functional leads to zero or close to zero band gaps. In particular, our mBJLDA results confirm experimental evidence that the minimum band gap occurs for As concentrations around x ≈0.3 . Furthermore, we investigate the dielectric function of these compounds within the random phase approximation using both the Wu-Cohen GGA and the mBJLDA functionals. While the mBJLDA results of our fully first-principles calculations show good agreement of the peak positions in ɛ2(ω ) with experiments, the peaks in the optical spectra based on the Wu-Cohen GGA band structure appear redshifted compared to experiment. We further identify the interband transitions responsible for the structures in the spectra. Looking at the optical matrix element, we note that the major peaks are dominated by transition from the Sb 5 p (As 4 p ) states to In s states for InSb and InAs0.25Sb0.75 (InAs, InAs0.75Sb0.25 , and InAs0.5Sb0.5 ).

  17. Silicon-chip mid-infrared frequency comb generation

    NASA Astrophysics Data System (ADS)

    Griffith, Austin G.; Lau, Ryan K. W.; Cardenas, Jaime; Okawachi, Yoshitomo; Mohanty, Aseema; Fain, Romy; Lee, Yoon Ho Daniel; Yu, Mengjie; Phare, Christopher T.; Poitras, Carl B.; Gaeta, Alexander L.; Lipson, Michal

    2015-02-01

    Optical frequency combs are a revolutionary light source for high-precision spectroscopy because of their narrow linewidths and precise frequency spacing. Generation of such combs in the mid-infrared spectral region (2-20 μm) is important for molecular gas detection owing to the presence of a large number of absorption lines in this wavelength regime. Microresonator-based frequency comb sources can provide a compact and robust platform for comb generation that can operate with relatively low optical powers. However, material and dispersion engineering limitations have prevented the realization of an on-chip integrated mid-infrared microresonator comb source. Here we demonstrate a complementary metal-oxide-semiconductor compatible platform for on-chip comb generation using silicon microresonators, and realize a broadband frequency comb spanning from 2.1 to 3.5 μm. This platform is compact and robust and offers the potential to be versatile for use outside the laboratory environment for applications such as real-time monitoring of atmospheric gas conditions.

  18. Analysis of Replicating Yeast Chromosomes by DNA Combing.

    PubMed

    Gallo, David; Wang, Gang; Yip, Christopher M; Brown, Grant W

    2016-01-01

    Molecular combing of DNA fibers is a powerful technique to monitor origin usage and DNA replication fork progression in the budding yeast Saccharomyces cerevisiae. In contrast to traditional flow cytometry, microarray, or sequencing techniques, which provide population-level data, DNA combing provides DNA replication profiles of individual molecules. DNA combing uses yeast strains that express human thymidine kinase, which facilitates the incorporation of thymidine analogs into nascent DNA. First, DNA is isolated and stretched uniformly onto silanized glass coverslips. Following immunodetection with antibodies that recognize the thymidine analog and the DNA, the DNA fibers are imaged using a fluorescence microscope. Finally, the lengths of newly replicated DNA tracks are measured and converted to base pairs, allowing calculations of the speed of the replication fork and of interorigin distances. DNA combing can be applied to monitor replication defects caused by gene mutations or by chemical agents that induce replication stress. Here, we present a methodology for studying replicating yeast chromosomes by molecular DNA combing. We begin with procedures for the preparation of silanized coverslips and for assembly of a DNA combing machine (DCM) and conclude by presenting a detailed protocol for molecular DNA combing in yeast. PMID:26832684

  19. Coherent terabit communications with microresonator Kerr frequency combs

    PubMed Central

    Pfeifle, Joerg; Brasch, Victor; Lauermann, Matthias; Yu, Yimin; Wegner, Daniel; Herr, Tobias; Hartinger, Klaus; Schindler, Philipp; Li, Jingshi; Hillerkuss, David; Schmogrow, Rene; Weimann, Claudius; Holzwarth, Ronald; Freude, Wolfgang; Leuthold, Juerg; Kippenberg, Tobias J.; Koos, Christian

    2014-01-01

    Optical frequency combs have the potential to revolutionize terabit communications1. Generation of Kerr combs in nonlinear microresonators2 represents a particularly promising option3 enabling line spacings of tens of GHz. However, such combs may exhibit strong phase noise4-6, which has made high-speed data transmission impossible up to now. Here we demonstrate that systematic adjustment of pump conditions for low phase noise4,7-9 enables coherent data transmission with advanced modulation formats that pose stringent requirements on the spectral purity of the comb. In a first experiment, we encode a data stream of 392 Gbit/s on a Kerr comb using quadrature phase shift keying (QPSK) and 16-state quadrature amplitude modulation (16QAM). A second experiment demonstrates feedback-stabilization of the comb and transmission of a 1.44 Tbit/s data stream over up to 300 km. The results show that Kerr combs meet the highly demanding requirements of coherent communications and thus offer an attractive solution towards chip-scale terabit/s transceivers. PMID:24860615

  20. Frequency comb metrology with an optical parametric oscillator.

    PubMed

    Balskus, K; Schilt, S; Wittwer, V J; Brochard, P; Ploetzing, T; Jornod, N; McCracken, R A; Zhang, Z; Bartels, A; Reid, D T; Südmeyer, T

    2016-04-18

    We report on the first demonstration of absolute frequency comb metrology with an optical parametric oscillator (OPO) frequency comb. The synchronously-pumped OPO operated in the 1.5-µm spectral region and was referenced to an H-maser atomic clock. Using different techniques, we thoroughly characterized the frequency noise power spectral density (PSD) of the repetition rate frep, of the carrier-envelope offset frequency fCEO, and of an optical comb line νN. The comb mode optical linewidth at 1557 nm was determined to be ~70 kHz for an observation time of 1 s from the measured frequency noise PSD, and was limited by the stability of the microwave frequency standard available for the stabilization of the comb repetition rate. We achieved a tight lock of the carrier envelope offset frequency with only ~300 mrad residual integrated phase noise, which makes its contribution to the optical linewidth negligible. The OPO comb was used to measure the absolute optical frequency of a near-infrared laser whose second-harmonic component was locked to the F = 2→3 transition of the 87Rb D2 line at 780 nm, leading to a measured transition frequency of νRb = 384,228,115,346 ± 16 kHz. We performed the same measurement with a commercial fiber-laser comb operating in the 1.5-µm region. Both the OPO comb and the commercial fiber comb achieved similar performance. The measurement accuracy was limited by interferometric noise in the fibered setup of the Rb-stabilized laser. PMID:27137274

  1. Precision spectroscopy using a partially stabilized frequency comb.

    PubMed

    Lyon, M; Bergeson, S D

    2014-08-10

    We present a simple method for precision spectroscopy using an optical frequency comb. One mode of a 1GHz repetition rate mode-locked Ti:sapphire laser is offset-locked to an Rb-stabilized diode laser. This partially stabilized frequency comb stays locked, unattended, for hours at a time. Using the measured offset frequency and repetition rate, we calculate the frequency of each comb mode with absolute uncertainty of about 10kHz in a 10s measurement window. We demonstrate the capabilities and limitations of this approach with measurements in Rb, Cs, and Ca. PMID:25320925

  2. All-optically stabilized frequency comb

    NASA Astrophysics Data System (ADS)

    Okubo, Sho; Gunji, Kenta; Onae, Atsushi; Schramm, Malte; Nakamura, Keisuke; Hong, Feng-Lei; Hattori, Toshiaki; Hosaka, Kazumoto; Inaba, Hajime

    2015-12-01

    We present an all-optically stabilized, erbium-doped mode-locked fiber laser with an optically pumped ytterbium-doped fiber. The mode-locked fiber laser has two frequency-control actuators that are pump laser powers for erbium-doped and ytterbium-doped fibers. We investigate the frequency-control characteristics of the mode-locked laser and find that the fixed points for the two actuators are sufficiently apart from each other, realizing the simultaneous phase locking of the repetition and carrier envelope offset frequencies. We describe a long-term frequency measurement of an acetylene-stabilized laser at 1542 nm using an all-optically stabilized frequency comb.

  3. Combing gravitational hair in 2 + 1 dimensions

    NASA Astrophysics Data System (ADS)

    Donnelly, William; Marolf, Donald; Mintun, Eric

    2016-01-01

    The gravitational Gauss law requires any addition of energy to be accompanied by the addition of gravitational flux. The possible configurations of this flux for a given source may be called gravitational hair, and several recent works discuss gravitational observables (‘gravitational Wilson lines’) which create this hair in highly collimated ‘combed’ configurations. We construct and analyze time-symmetric classical solutions of 2 + 1 Einstein-Hilbert gravity such as might be created by smeared versions of such operators. We focus on the AdS3 case, where this hair is characterized by the profile of the boundary stress tensor; the desired solutions are those where the boundary stress tensor at initial time t = 0 agrees precisely with its vacuum value outside an angular interval [-α ,α ]. At linear order in source strength the energy is independent of the combing parameter α, but nonlinearities cause the full energy to diverge as α \\to 0. In general, solutions with combed gravitational flux also suffer from what we call displacement from their naive location. For weak sources and large α one may set the displacement to zero by further increasing the energy, though for strong sources and small α we find no preferred notion of a zero-displacement solution. In the latter case we conclude that naively expected gravitational Wilson lines do not exist. In the zero-displacement case, taking the AdS scale ℓ to infinity gives finite-energy flux-directed solutions that may be called asymptotically flat.

  4. A Genomic Duplication is Associated with Ectopic Eomesodermin Expression in the Embryonic Chicken Comb and Two Duplex-comb Phenotypes

    PubMed Central

    Dorshorst, Ben; Rubin, Carl-Johan; Ashwell, Chris; Gourichon, David; Tixier-Boichard, Michèle; Hallböök, Finn; Andersson, Leif

    2015-01-01

    Duplex-comb (D) is one of three major loci affecting comb morphology in the domestic chicken. Here we show that the two Duplex-comb alleles, V-shaped (D*V) and Buttercup (D*C), are both associated with a 20 Kb tandem duplication containing several conserved putative regulatory elements located 200 Kb upstream of the eomesodermin gene (EOMES). EOMES is a T-box transcription factor that is involved in mesoderm specification during gastrulation. In D*V and D*C chicken embryos we find that EOMES is ectopically expressed in the ectoderm of the comb-developing region as compared to wild-type embryos. The confinement of the ectopic expression of EOMES to the ectoderm is in stark contrast to the causal mechanisms underlying the two other major comb loci in the chicken (Rose-comb and Pea-comb) in which the transcription factors MNR2 and SOX5 are ectopically expressed strictly in the mesenchyme. Interestingly, the causal mutations of all three major comb loci in the chicken are now known to be composed of large-scale structural genomic variants that each result in ectopic expression of transcription factors. The Duplex-comb locus also illustrates the evolution of alleles in domestic animals, which means that alleles evolve by the accumulation of two or more consecutive mutations affecting the phenotype. We do not yet know whether the V-shaped or Buttercup allele correspond to the second mutation that occurred on the haplotype of the original duplication event. PMID:25789773

  5. A genomic duplication is associated with ectopic eomesodermin expression in the embryonic chicken comb and two duplex-comb phenotypes.

    PubMed

    Dorshorst, Ben; Harun-Or-Rashid, Mohammad; Bagherpoor, Alireza Jian; Rubin, Carl-Johan; Ashwell, Chris; Gourichon, David; Tixier-Boichard, Michèle; Hallböök, Finn; Andersson, Leif

    2015-03-01

    Duplex-comb (D) is one of three major loci affecting comb morphology in the domestic chicken. Here we show that the two Duplex-comb alleles, V-shaped (D*V) and Buttercup (D*C), are both associated with a 20 Kb tandem duplication containing several conserved putative regulatory elements located 200 Kb upstream of the eomesodermin gene (EOMES). EOMES is a T-box transcription factor that is involved in mesoderm specification during gastrulation. In D*V and D*C chicken embryos we find that EOMES is ectopically expressed in the ectoderm of the comb-developing region as compared to wild-type embryos. The confinement of the ectopic expression of EOMES to the ectoderm is in stark contrast to the causal mechanisms underlying the two other major comb loci in the chicken (Rose-comb and Pea-comb) in which the transcription factors MNR2 and SOX5 are ectopically expressed strictly in the mesenchyme. Interestingly, the causal mutations of all three major comb loci in the chicken are now known to be composed of large-scale structural genomic variants that each result in ectopic expression of transcription factors. The Duplex-comb locus also illustrates the evolution of alleles in domestic animals, which means that alleles evolve by the accumulation of two or more consecutive mutations affecting the phenotype. We do not yet know whether the V-shaped or Buttercup allele correspond to the second mutation that occurred on the haplotype of the original duplication event. PMID:25789773

  6. Frequency comb selection enabled flexible all optical Nyquist pulse generation

    NASA Astrophysics Data System (ADS)

    Fang, Yuan; Yu, Jianjun; Zhang, Junwen; Li, Xinying; Chi, Nan; Xiao, Jiangnan

    2015-08-01

    In this paper, we propose and experimentally demonstrate flexible all optical Nyquist pulse generation enabled by frequency comb selection with cascaded intensity modulators and tunable optical band-pass filters. Cascaded intensity modulators are used to generate frequency-locked optical comb with flat amplitude and linear phase with up to 15 tones. Arbitrary frequency comb selection based on tunable optical band-pass filters allows the control of the pulse width and repetitive period of the high quality sinc-shaped Nyquist pulse. The optical spectra of the selected 3 and 7 tones frequency comb and the corresponding time-domain waveforms are measured in experiment and simulated by software, respectively. Experimental results conform well to the simulation results which verifies the feasibility of our scheme. The scheme we propose is with excellent flexibility in Nyquist pulse generation and is suitable for high capacity optical transmission system.

  7. Quantum memory based on a spatiospectral atomic comb

    NASA Astrophysics Data System (ADS)

    Tian, Mingzhen; Vega, Devin; Dilles, Jacob

    2013-04-01

    An atomic comb structure consisting of both spatial and spectral components is proposed for the implementation of quantum memory using inhomogeneously broadened atomic ensembles, such as rare-earth ions trapped in solids. The spatiospectral comb can be prepared in two-level atoms provided a third energy level is available for atomic population storage. The output photon is retrieved from the memory as a spatially diffracted photon echo. The angle between the input and output directions is controlled by the spatial component of the atomic comb. The memory efficiency is analyzed using coupled wave theory, which results in memory efficiency varying with the retrieval angle: 54.1% in collinear, 81.6% in perpendicular, and 100% in counterpropagating configurations. An experimental method for creating a multidimensional atomic comb is suggested.

  8. CombFunc: predicting protein function using heterogeneous data sources

    PubMed Central

    Wass, Mark N.; Barton, Geraint; Sternberg, Michael J. E.

    2012-01-01

    Only a small fraction of known proteins have been functionally characterized, making protein function prediction essential to propose annotations for uncharacterized proteins. In recent years many function prediction methods have been developed using various sources of biological data from protein sequence and structure to gene expression data. Here we present the CombFunc web server, which makes Gene Ontology (GO)-based protein function predictions. CombFunc incorporates ConFunc, our existing function prediction method, with other approaches for function prediction that use protein sequence, gene expression and proteinprotein interaction data. In benchmarking on a set of 1686 proteins CombFunc obtains precision and recall of 0.71 and 0.64 respectively for gene ontology molecular function terms. For biological process GO terms precision of 0.74 and recall of 0.41 is obtained. CombFunc is available at http://www.sbg.bio.ic.ac.uk/combfunc. PMID:22641853

  9. High density terahertz frequency comb produced by coherent synchrotron radiation

    PubMed Central

    Tammaro, S.; Pirali, O.; Roy, P.; Lampin, J.-F.; Ducournau, G.; Cuisset, A.; Hindle, F.; Mouret, G.

    2015-01-01

    Frequency combs have enabled significant progress in frequency metrology and high-resolution spectroscopy extending the achievable resolution while increasing the signal-to-noise ratio. In its coherent mode, synchrotron radiation is accepted to provide an intense terahertz continuum covering a wide spectral range from about 0.1 to 1 THz. Using a dedicated heterodyne receiver, we reveal the purely discrete nature of this emission. A phase relationship between the light pulses leads to a powerful frequency comb spanning over one decade in frequency. The comb has a mode spacing of 846 kHz, a linewidth of about 200 Hz, a fractional precision of about 2 × 10−10 and no frequency offset. The unprecedented potential of the comb for high-resolution spectroscopy is demonstrated by the accurate determination of pure rotation transitions of acetonitrile. PMID:26190043

  10. Optimal Sharpening of Compensated Comb Decimation Filters: Analysis and Design

    PubMed Central

    Troncoso Romero, David Ernesto

    2014-01-01

    Comb filters are a class of low-complexity filters especially useful for multistage decimation processes. However, the magnitude response of comb filters presents a droop in the passband region and low stopband attenuation, which is undesirable in many applications. In this work, it is shown that, for stringent magnitude specifications, sharpening compensated comb filters requires a lower-degree sharpening polynomial compared to sharpening comb filters without compensation, resulting in a solution with lower computational complexity. Using a simple three-addition compensator and an optimization-based derivation of sharpening polynomials, we introduce an effective low-complexity filtering scheme. Design examples are presented in order to show the performance improvement in terms of passband distortion and selectivity compared to other methods based on the traditional Kaiser-Hamming sharpening and the Chebyshev sharpening techniques recently introduced in the literature. PMID:24578674

  11. Universality of comb structures in strong-field quantum electrodynamics

    NASA Astrophysics Data System (ADS)

    Krajewska, Katarzyna; Kami?ski, Jerzy

    2015-05-01

    We demonstrate a new mechanism for coherent comb generation in both radiation and matter domains, which is by using strong-field quantum electrodynamics processes. Specifically, we demonstrate this for nonlinear Compton scattering which has the potential to generate frequency combs extending towards the ?-ray spectral region and combs of ultra-relativistic electrons extending towards the MeV regime. Moreover, we show that coherent energy combs of positrons (electrons) emerge in laser-induced pair creation processes such as the Breit-Wheeler process, proving the universality of the proposed mechanism. We acknowledge the support from the Kosciuszko Foundation (KK) and from the Polish National Science Center (NCN), under Grant No. 2012/05/B/ST2/02547 (JZK).

  12. High density terahertz frequency comb produced by coherent synchrotron radiation.

    PubMed

    Tammaro, S; Pirali, O; Roy, P; Lampin, J-F; Ducournau, G; Cuisset, A; Hindle, F; Mouret, G

    2015-01-01

    Frequency combs have enabled significant progress in frequency metrology and high-resolution spectroscopy extending the achievable resolution while increasing the signal-to-noise ratio. In its coherent mode, synchrotron radiation is accepted to provide an intense terahertz continuum covering a wide spectral range from about 0.1 to 1 THz. Using a dedicated heterodyne receiver, we reveal the purely discrete nature of this emission. A phase relationship between the light pulses leads to a powerful frequency comb spanning over one decade in frequency. The comb has a mode spacing of 846 kHz, a linewidth of about 200 Hz, a fractional precision of about 2 × 10(-10) and no frequency offset. The unprecedented potential of the comb for high-resolution spectroscopy is demonstrated by the accurate determination of pure rotation transitions of acetonitrile. PMID:26190043

  13. Doppler Cooling Trapped Ions with a UV Frequency Comb

    NASA Astrophysics Data System (ADS)

    Davila-Rodriguez, Josue; Ozawa, Akira; Hänsch, Theodor W.; Udem, Thomas

    2016-01-01

    We demonstrate Doppler cooling of trapped magnesium ions using a frequency comb at 280 nm obtained from a frequency tripled Ti:sapphire laser. A comb line cools on the 3 s1 /2-3 p3 /2 transition, while the nearest blue-detuned comb line contributes negligible heating. We observe the cooling-heating transition and long-term cooling of ion chains with several sympathetically cooled ions. Spatial thermometry shows that the ion is cooled to near the Doppler limit. Doppler cooling with frequency combs has the potential to open many additional atomic species to laser cooling by reaching further into the vacuum and extreme ultraviolet via high-harmonic generation and by providing a broad bandwidth from which multiple excitation sidebands can be obtained.

  14. Frequency stabilisation of femtosecond frequency combs with a reference laser

    SciTech Connect

    Bagayev, S N; Pivtsov, V S; Zheltikov, Aleksei M

    2002-04-30

    A solution to the key problem of femtosecond metrology - elimination of the frequency offset related to the intracavity dispersion of a femtosecond laser - is proposed. The proposed method involves stabilisation of the intermode interval between equidistant spectral components in a frequency comb produced by a mode-locked femtosecond laser by phase-locking the frequency difference between a pair of discrete spectral components in this comb to the frequency of a reference laser. An introduction of a nonlinear-optical crystal for frequency doubling into the scheme for frequency-comb stabilisation allows the frequency offset related to the intracavity dispersion of the femtosecond laser to be eliminated, thus suggesting the way for absolute stabilisation of frequency combs generated by femtosecond mode-locked lasers. Radiation of a reference laser with such an approach plays the role of an anchor in the femtosecond clockwork. (control of laser radiation parameters)

  15. Adaptive real-time dual-comb spectroscopy

    PubMed Central

    Ideguchi, Takuro; Poisson, Antonin; Guelachvili, Guy; Picqué, Nathalie; Hänsch, Theodor W.

    2014-01-01

    The spectrum of a laser frequency comb consists of several hundred thousand equally spaced lines over a broad spectral bandwidth. Such frequency combs have revolutionized optical frequency metrology and they now hold much promise for significant advances in a growing number of applications including molecular spectroscopy. Despite an intriguing potential for the measurement of molecular spectra spanning tens of nanometres within tens of microseconds at Doppler-limited resolution, the development of dual-comb spectroscopy is hindered by the demanding stability requirements of the laser combs. Here we overcome this difficulty and experimentally demonstrate a concept of real-time dual-comb spectroscopy, which compensates for laser instabilities by electronic signal processing. It only uses free-running mode-locked lasers without any phase-lock electronics. We record spectra spanning the full bandwidth of near-infrared fibre lasers with Doppler-limited line profiles highly suitable for measurements of concentrations or line intensities. Our new technique of adaptive dual-comb spectroscopy offers a powerful transdisciplinary instrument for analytical sciences. PMID:24572636

  16. Parentage and relatedness in polyandrous comb-crested jacanas using ISSRs

    USGS Publications Warehouse

    Haig, Susan M.; Mace, Terrence R.; Mullins, Thomas D.

    2003-01-01

    In this article we present the first analysis of parentage and relatedness in a natural vertebrate population, using Intersimple Sequence Repeat (ISSR) markers. Thus, 28 ISSR markers were used in a study of a sex-role reversed, simultaneously polyandrous shorebird from northeastern Australia, the comb-crested jacana (Irediparra gallinacea). Assessment of parentage was based on comparison of field observations, novel bands, individual-specific bands found in 7/9 males and 4/6 females, and a 99% CI exclusion criteria. Integrating results from these approaches resulted in confirmation of paternity in all 36 chicks. In only one case (2.8% of chicks) was a co-mate assigned paternity. Thus, comb-crested jacanas appear to be genetically monogamous. These results showed resemblance to sequentially polyandrous birds but differed from the simultaneously polyandrous wattled jacana ( Jacana jacana; Emlen et al. 1998). A significant relationship between relatedness and ISSR similarity resulted in recognition that 14/15 adults sampled may be related to at least one other adult by 0.25 or more. Lack of dispersal may be explained by physical limitations and adequate regional habitat. ISSRs proved to be simple and helpful in resolving these issues.

  17. Safe sex

    MedlinePlus

    Safe sex means taking steps before and during sex that can prevent you from getting an infection, or from ... the skin around the genital area. Before having sex: Get to know your partner and discuss your ...

  18. Broadband Comb-Resolved Cavity Enhanced Spectrometer with Graphene Modulator

    NASA Astrophysics Data System (ADS)

    Lee, Kevin; Mohr, Christian; Jiang, Jie; Fermann, Martin; Lee, Chien-Chung; Schibli, Thomas R.; Kowzan, Grzegorz; Maslowski, Piotr

    2015-06-01

    Optical cavities enhance sensitivity in absorption spectroscopy. While this is commonly done with single wavelengths, broad bandwidths can be coupled into the cavity using frequency combs. The combination of cavity enhancement and broad bandwidth allows simultaneous measurement of tens of transitions with high signal-to-noise for even weak near-infrared transitions. This removes the need for time-consuming sequencing acquisition or long-term averaging, so any systematic errors from long-term drifts of the experimental setup or slow changes of sample composition are minimized. Resolving comb lines provides a high accuracy, absolute frequency axis. This is of great importance for gas metrology and data acquisition for future molecular lines databases, and can be applied to simultaneous trace-gas detection of gas mixtures. Coupling of a frequency comb into a cavity can be complex, so we introduce and demonstrate a simplification. The Pound-Drever-Hall method for locking a cavity and a frequency comb together requires a phase modulation of the laser output. We use the graphene modulator that is already in the Tm fiber laser cavity for controlling the carrier envelope offset of the frequency comb, rather than adding a lossy external modulator. The graphene modulator can operate at frequencies of over 1~ MHz, which is sufficient for controlling the laser cavity length actuator which operates below 100~kHz. We match the laser cavity length to fast variations of the enhancement cavity length. Slow variations are stabilized by comparison of the pulse repetition rate to a GPS reference. The carrier envelope offset is locked to a constant value chosen to optimize the transmitted spectrum. The transmitted pulse train is a stable frequency comb suitable for long measurements, including the acquisition of comb-resolved Fourier transform spectra with a minimum absorption coefficient of about 210-7 wn. For our 38 cm long enhancement cavity, the comb spacing is 394~MHz. With our 300 wn bandwidth at 2 ?m, we simultaneously measure the full comb line resolved CO_2 vibrational manifold at 4850 wn. Other spectral ranges can be accessed by using graphene with different gain fibers or nonlinear frequency conversion.

  19. Solution and Melt Rheology of Polypropylene Comb and Star Polymers

    NASA Astrophysics Data System (ADS)

    Ghosh, Arnav; Colby, Ralph H.; Rose, Jeffrey M.; Cherian, Anna E.; Coates, Geoffrey W.

    2006-03-01

    Syndiotactic polypropylene macromonomer arms have been prepared by coordination-insertion polymerization. These arms have been made into polypropylene star polymers by the homopolymerization of the syndiotactic arms with a living alkene polymerization catalyst. The macromonomer arms have also been randomly copolymerized with propylene using rac-dimethylsilyl(2-methyl-4-phenylindenyl) zirconium dichloride catalysts to make polypropylene combs. Consequently we have star polymers and a series of comb polymers with different backbone lengths that are all made from the same macromonomer arms. We compare linear viscoelastic data on star and comb polypropylene melts and solutions in squalane to predictions of the tube dilation model and the tube model without tube dilation. The ratio of comb terminal relaxation time to star terminal relaxation time eliminates the friction coefficient and allows determination of the extent of tube dilation the backbone experiences when it relaxes. The concentration dependence of the comb/star terminal relaxation time ratio can be described by either model, owing to adjustable parameters that are not known apriori, so independent means to evaluate those parameters will be discussed.

  20. Tunable frequency combs based on dual microring resonators.

    PubMed

    Miller, Steven A; Okawachi, Yoshitomo; Ramelow, Sven; Luke, Kevin; Dutt, Avik; Farsi, Alessandro; Gaeta, Alexander L; Lipson, Michal

    2015-08-10

    In order to achieve efficient parametric frequency comb generation in microresonators, external control of coupling between the cavity and the bus waveguide is necessary. However, for passive monolithically integrated structures, the coupling gap is fixed and cannot be externally controlled, making tuning the coupling inherently challenging. We design a dual-cavity coupled microresonator structure in which tuning one ring resonance frequency induces a change in the overall cavity coupling condition. We demonstrate wide extinction tunability with high efficiency by engineering the ring coupling conditions. Additionally, we note a distinct dispersion tunability resulting from coupling two cavities of slightly different path lengths, and present a new method of modal dispersion engineering. Our fabricated devices consist of two coupled high quality factor silicon nitride microresonators, where the extinction ratio of the resonances can be controlled using integrated microheaters. Using this extinction tunability, we optimize comb generation efficiency as well as provide tunability for avoiding higher-order mode-crossings, known for degrading comb generation. The device is able to provide a 110-fold improvement in the comb generation efficiency. Finally, we demonstrate open eye diagrams using low-noise phase-locked comb lines as a wavelength-division multiplexing channel. PMID:26367998

  1. Phrenology, heredity and progress in George Combe's Constitution of Man.

    PubMed

    Jenkins, Bill

    2015-09-01

    The Constitution of Man by George Combe (1828) was probably the most influential phrenological work of the nineteenth century. It not only offered an exposition of the phrenological theory of the mind, but also presented Combe's vision of universal human progress through the inheritance of acquired mental attributes. In the decades before the publication of Darwin's Origin of Species, the Constitution was probably the single most important vehicle for the dissemination of naturalistic progressivism in the English-speaking world. Although there is a significant literature on the social and cultural context of phrenology, the role of heredity in Combe's thought has been less thoroughly explored, although both John van Wyhe and Victor L. Hilts have linked Combe's views on heredity with the transformist theories of Jean-Baptiste Lamarck. In this paper I examine the origin, nature and significance of his ideas and argue that Combe's hereditarianism was not directly related to Lamarckian transformism but formed part of a wider discourse on heredity in the early nineteenth century. PMID:25998794

  2. Brood comb as a humidity buffer in honeybee nests

    NASA Astrophysics Data System (ADS)

    Ellis, Michael B.; Nicolson, Sue W.; Crewe, Robin M.; Dietemann, Vincent

    2010-04-01

    Adverse environmental conditions can be evaded, tolerated or modified in order for an organism to survive. During their development, some insect larvae spin cocoons which, in addition to protecting their occupants against predators, modify microclimatic conditions, thus facilitating thermoregulation or reducing evaporative water loss. Silk cocoons are spun by honeybee ( Apis mellifera) larvae and subsequently incorporated into the cell walls of the wax combs in which they develop. The accumulation of this hygroscopic silk in the thousands of cells used for brood rearing may significantly affect nest homeostasis by buffering humidity fluctuations. This study investigates the extent to which the comb may influence homeostasis by quantifying the hygroscopic capacity of the cocoons spun by honeybee larvae. When comb containing cocoons was placed at high humidity, it absorbed 11% of its own mass in water within 4 days. Newly drawn comb composed of hydrophobic wax and devoid of cocoons absorbed only 3% of its own mass. Therefore, the accumulation of cocoons in the comb may increase brood survivorship by maintaining a high and stable humidity in the cells.

  3. X-ray frequency combs from optically controlled resonance fluorescence

    NASA Astrophysics Data System (ADS)

    Cavaletto, Stefano M.; Harman, Zoltán; Buth, Christian; Keitel, Christoph H.

    2013-12-01

    An x-ray pulse-shaping scheme is put forward for imprinting an optical frequency comb onto the radiation emitted on a driven x-ray transition, thus producing an x-ray frequency comb. A four-level system is used to describe the level structure of N ions driven by narrow-bandwidth x rays, an optical auxiliary laser, and an optical frequency comb. By including many-particle enhancement of the emitted resonance fluorescence, a spectrum is predicted consisting of equally spaced narrow lines which are centered on an x-ray transition energy and separated by the same tooth spacing as the driving optical frequency comb. Given an x-ray reference frequency, our comb could be employed to determine an unknown x-ray frequency. While relying on the quality of the light fields used to drive the ensemble of ions, the model has validity at energies from the 100 eV to the keV range.

  4. Laser cooling and trapping with optical frequency combs

    NASA Astrophysics Data System (ADS)

    Jayich, Andrew; Long, Xueping; Ransford, Anthony; Wang, Anna; Campbell, Wesley

    2015-05-01

    A large number of atoms and molecules are difficult to control with continuous wave lasers because generating sufficient power at all of the necessary wavelengths is technologically challenging. Mode-locked lasers, through their enhanced efficiency of nonlinear frequency conversion, provide some of these hard to access wavelengths. As a step towards control of exotic atoms and molecules we report on laser cooling and trapping of atoms using an optical frequency comb in two different regimes. Using a single comb, we have created a simultaneous dual-species (isotopes) MOT, demonstrating that multiple comb teeth can be used in parallel to cool and confine species requiring many cw lasers. Separately, we demonstrate comb-based laser cooling on a two-photon transition, which efficiently uses the full time-averaged optical power of the entire comb. Our progress toward extending this to include trapping by making a MOT using this two-photon transition is presented. This work is supported by the National Science Foundation.

  5. 1-GHz harmonically pumped femtosecond optical parametric oscillator frequency comb.

    PubMed

    Balskus, K; Leitch, S M; Zhang, Z; McCracken, R A; Reid, D T

    2015-01-26

    We present the first example of a femtosecond optical parametric oscillator frequency comb harmonically-pumped by a 333-MHz Ti:sapphire laser to achieve a stabilized signal comb at 1-GHz mode spacing in the 1.1-1.6-m wavelength band. Simultaneous locking of the comb carrier-envelope-offset and repetition frequencies is achieved with uncertainties over 1 s of 0.27 Hz and 5 mHz respectively, which are comparable with those of 0.27 Hz and 1.5 mHz achieved for 333-MHz fundamental pumping. The phase-noise power-spectral density of the CEO frequency integrated from 1 Hz-64 kHz was 2.8 rad for the harmonic comb, 1.0 rad greater than for fundamental pumping. The results show that harmonic operation does not substantially compromise the frequency-stability of the comb, which is shown to be limited only by the Rb atomic frequency reference used. PMID:25835887

  6. Characterization of a partially-stabilized frequency comb

    NASA Astrophysics Data System (ADS)

    Gold Dahl, M. E.; Erikson, Alex; Woodbury, Daniel; Bergeson, Scott

    2015-05-01

    We present measurements of well-known frequency intervals in Cs, Rb, and Ca. These measurements are used to determine the accuracy of a partially-stabilized ti:sapphire frequency comb. One mode of our frequency comb is offset-locked to a Rb-stabilized diode laser. The comb's repetition rate is counted but not locked. A second laser is used to probe well-known atomic transitions in Cs, Rb, and Ca. We describe our offset locking and scanning techniques and demonstrate a frequency precision of 10 kHz in a 30 second measurement time. The accuracy of our laser frequency interval measurements is approximately 40 kHz. However, cell-based frequency references can be off by several hundred kHz. Research supported by the National Science Foundation (Grant No. PHY-0969856) and the Air Force (Grant No. FA9950-12-1-0308).

  7. Software reconfigurable highly flexible gain switched optical frequency comb source.

    PubMed

    Pascual, M Deseada Gutierrez; Zhou, Rui; Smyth, Frank; Anandarajah, Prince M; Barry, Liam P

    2015-09-01

    The authors present the performance and noise properties of a software reconfigurable, FSR and wavelength tunable gain switched optical frequency comb source. This source, based on the external injection of a temperature tuned Fabry-Pérot laser diode, offers quasi-continuous wavelength tunability over the C-band (30nm) and FSR tunability ranging from 6 to 14GHz. The results achieved demonstrate the excellent spectral quality of the comb tones (RIN ~-130dB/Hz and low phase noise of 300kHz) and its outstanding stability (with fluctuations of the individual comb tones of less than 0.5dB in power and 5pm in wavelength, characterized over 24hours) highlighting its suitability for employment in next generation flexible optical transmission networks. PMID:26368425

  8. Quantum cascade laser combs: effects of modulation and dispersion.

    PubMed

    Villares, Gustavo; Faist, Jérôme

    2015-01-26

    Frequency comb formation in quantum cascade lasers is studied theoretically using a Maxwell-Bloch formalism based on a modal decomposition, where dispersion is considered. In the mid-infrared, comb formation persists in the presence of weak cavity dispersion (500 fs2 mm-1) but disappears when much larger values are used (30'000 fs2 mm-1). Active modulation at the round-trip frequency is found to induce mode-locking in THz devices, where the upper state lifetime is in the tens of picoseconds. Our results show that mode-locking based on four-wave mixing in broadband gain, low dispersion cavities is the most promising way of achieving broadband quantum cascade laser frequency combs. PMID:25835922

  9. Methods and apparatus for broadband frequency comb stabilization

    SciTech Connect

    Cox, Jonathan A; Kaertner, Franz X

    2015-03-17

    Feedback loops can be used to shift and stabilize the carrier-envelope phase of a frequency comb from a mode-locked fibers laser or other optical source. Compared to other frequency shifting and stabilization techniques, feedback-based techniques provide a wideband closed-loop servo bandwidth without optical filtering, beam pointing errors, or group velocity dispersion. It also enables phase locking to a stable reference, such as a Ti:Sapphire laser, continuous-wave microwave or optical source, or self-referencing interferometer, e.g., to within 200 mrad rms from DC to 5 MHz. In addition, stabilized frequency combs can be coherently combined with other stable signals, including other stabilized frequency combs, to synthesize optical pulse trains with pulse durations of as little as a single optical cycle. Such a coherent combination can be achieved via orthogonal control, using balanced optical cross-correlation for timing stabilization and balanced homodyne detection for phase stabilization.

  10. Broadband degenerate OPO for mid-infrared frequency comb generation.

    PubMed

    Leindecker, Nick; Marandi, Alireza; Byer, Robert L; Vodopyanov, Konstantin L

    2011-03-28

    We present a new technique suitable for generating broadband phase- and frequency-locked frequency combs in the mid-infrared. Our source is based on a degenerate optical parametric oscillator (OPO) which rigorously both down-converts and augments the spectrum of a pump frequency comb provided by a commercial mode-locked near-IR laser. Low intracavity dispersion, combined with extensive cross-mixing of comb components, results in extremely broad instantaneous mid-IR bandwidths. We achieve an output power of 60 mW and 20 dB bandwidth extending from 2500 to 3800 nm. Among other applications, such a source is well-suited for coherent Fourier-transform spectroscopy in the absorption-rich mid-IR 'molecular fingerprint' region. PMID:21451655

  11. Brillouin filtering of optical combs for narrow linewidth frequency synthesis

    NASA Astrophysics Data System (ADS)

    Galindo-Santos, Juan; Velasco, Aitor V.; Carrasco-Sanz, Ana; Corredera, Pedro

    2016-05-01

    We report a tunable monochromatic source generation scheme, based on Brillouin filtering of a self-referenced optical frequency comb. The system benefits from the high stability and mode linewidth of the frequency comb, significantly improving the performance of the original laser source used as Brillouin pump. A synthesized frequency with stability under 4×10-11 and a linewidth under 75 kHz was experimentally demonstrated for two separate pump lasers in the C-band. The proposed monochromatic source can be tuned with high precision in a very broad band by combining a coarse control with the pumping source and a fine control with the optical frequency comb references. In our experimental setup, coarse and fine tuning resolutions were 4 MHz and 20 Hz, respectively. Influence of Brillouin pump fluctuations in the synthesized signal stability were also analyzed for observation times up to 104 s.

  12. Generation of Kerr frequency combs in a sapphire whispering gallery mode microresonator

    NASA Astrophysics Data System (ADS)

    Ilchenko, Vladimir S.; Savchenkov, Anatoliy A.; Matsko, Andrey B.; Maleki, Lute

    2014-12-01

    We study theoretically and demonstrate experimentally generation of coherent optical frequency combs in a sapphire whispering gallery mode resonator. We verify phase locking of the comb harmonics by demodulating the comb on a fast photodiode and by observing the production of a spectrally pure radio frequency signal. Because of excellent optical and superior mechanical properties of the material, the sapphire resonator is an excellent candidate for the on-chip device integration of the comb oscillator.

  13. Comparative reproduction of Varroa destructor in different types of Russian and Italian honey bee combs

    Technology Transfer Automated Retrieval System (TEKTRAN)

    We studied whether or not older comb supported less varroa reproduction in both Russian and Italian honey bees, whether Russian bees produced comb which inhibited varroa reproduction and whether comb foundation contained enough acaricides to influence varroa reproduction. The major differences foun...

  14. The generation of Continuous-Variable Entanglement Frequency Comb

    NASA Astrophysics Data System (ADS)

    Yu, Youbin; Cheng, Xiaomin; Wang, Huaijun; Shi, Zhongtao; Zhao, Junwei; Ji, Fengmin; Yin, Zhi; Wang, Yajuan

    2015-01-01

    Continuous-variable (CV) entanglement frequency comb can be produced by enhanced Raman scattering in an above-threshold optical oscillator cavity in which a hexagonally-poled LiTaO3 crystal resides as a Raman gain medium. The Stokes and anti-Stokes Raman signals are enhanced by a coupled quasi-phase-matching optical parametric process and the entanglement natures among these Raman signals and pump are demonstrated by applying a sufficient inseparability criterion for CV entanglement. Such entanglement frequency comb source with different frequencies and continuously tunable frequency interval may be very significant for the applications in quantum communication and networks.

  15. Monolithic device for modelocking and stabilization of frequency combs.

    PubMed

    Lee, C-C; Hayashi, Y; Silverman, K L; Feldman, A; Harvey, T; Mirin, R P; Schibli, T R

    2015-12-28

    We demonstrate a device that integrates a III-V semiconductor saturable absorber mirror with a graphene electro-optic modulator, which provides a monolithic solution to modelocking and noise suppression in a frequency comb. The device offers a pure loss modulation bandwidth exceeding 5 MHz and only requires a low voltage driver. This hybrid device provides not only compactness and simplicity in laser cavity design, but also small insertion loss, compared to the previous metallic-mirror-based modulators. We believe this work paves the way to portable and fieldable phase-coherent frequency combs. PMID:26831973

  16. Routes to spatiotemporal chaos in Kerr optical frequency combs

    SciTech Connect

    Coillet, Aurélien; Chembo, Yanne K.

    2014-03-15

    We investigate the various routes to spatiotemporal chaos in Kerr optical frequency combs, obtained through pumping an ultra-high Q-factor whispering-gallery mode resonator with a continuous-wave laser. The Lugiato–Lefever model is used to build bifurcation diagrams with regards to the parameters that are externally controllable, namely, the frequency and the power of the pumping laser. We show that the spatiotemporal chaos emerging from Turing patterns and solitons display distinctive dynamical features. Experimental spectra of chaotic Kerr combs are also presented for both cases, in excellent agreement with theoretical spectra.

  17. Routes to spatiotemporal chaos in Kerr optical frequency combs.

    PubMed

    Coillet, Aurélien; Chembo, Yanne K

    2014-03-01

    We investigate the various routes to spatiotemporal chaos in Kerr optical frequency combs, obtained through pumping an ultra-high Q-factor whispering-gallery mode resonator with a continuous-wave laser. The Lugiato-Lefever model is used to build bifurcation diagrams with regards to the parameters that are externally controllable, namely, the frequency and the power of the pumping laser. We show that the spatiotemporal chaos emerging from Turing patterns and solitons display distinctive dynamical features. Experimental spectra of chaotic Kerr combs are also presented for both cases, in excellent agreement with theoretical spectra. PMID:24697375

  18. Coherent combs in ionization by intense and short laser pulses

    NASA Astrophysics Data System (ADS)

    Krajewska, K.; Kamiński, J. Z.

    2016-03-01

    Photoionization of positive ions by a train of intense, short laser pulses is investigated within the relativistic strong field approximation, using the velocity gauge. The formation of broad peak structures in the high-energy domain of photoelectrons is observed and interpreted. The emergence of coherent photoelectron energy combs within these structures is demonstrated, and it is interpreted as the consequence of the Fraunhofer-type interference/diffraction of probability amplitudes of ionization from individual pulses comprising the train. Extensions to the coherent angular combs are also studied, and effects related to the radiation pressure are presented.

  19. The generation of Continuous-Variable Entanglement Frequency Comb

    PubMed Central

    Yu, Youbin; Cheng, Xiaomin; Wang, Huaijun; Shi, Zhongtao; Zhao, Junwei; Ji, Fengmin; Yin, Zhi; Wang, Yajuan

    2015-01-01

    Continuous-variable (CV) entanglement frequency comb can be produced by enhanced Raman scattering in an above-threshold optical oscillator cavity in which a hexagonally-poled LiTaO3 crystal resides as a Raman gain medium. The Stokes and anti-Stokes Raman signals are enhanced by a coupled quasi-phase-matching optical parametric process and the entanglement natures among these Raman signals and pump are demonstrated by applying a sufficient inseparability criterion for CV entanglement. Such entanglement frequency comb source with different frequencies and continuously tunable frequency interval may be very significant for the applications in quantum communication and networks. PMID:25600617

  20. Routes to spatiotemporal chaos in Kerr optical frequency combs

    SciTech Connect

    Coillet, Aurlien; Chembo, Yanne K.

    2014-03-15

    We investigate the various routes to spatiotemporal chaos in Kerr optical frequency combs, obtained through pumping an ultra-high Q-factor whispering-gallery mode resonator with a continuous-wave laser. The LugiatoLefever model is used to build bifurcation diagrams with regards to the parameters that are externally controllable, namely, the frequency and the power of the pumping laser. We show that the spatiotemporal chaos emerging from Turing patterns and solitons display distinctive dynamical features. Experimental spectra of chaotic Kerr combs are also presented for both cases, in excellent agreement with theoretical spectra.

  1. Spatiotemporal dynamics of Kerr-Raman optical frequency combs

    NASA Astrophysics Data System (ADS)

    Chembo, Yanne K.; Grudinin, Ivan S.; Yu, Nan

    2015-10-01

    Optical frequency combs generated with ultrahigh-Q whispering-gallery-mode resonators are expected to provide a compact, versatile, and energy-efficient source for the generation of coherent lightwave and microwave signals. So far, Kerr and Raman nonlinearities in these resonators have predominantly been investigated separately, even though both effects originate from the same third-order susceptibility. We present a spatiotemporal formalism for the theoretical understanding of these Kerr-Raman combs, which allows us to describe the complex interplay between both nonlinearities and all-order dispersion. These theoretical findings are successfully compared with experiments performed with ultrahigh-Q calcium and magnesium fluoride resonators.

  2. The generation of continuous-variable entanglement frequency comb.

    PubMed

    Yu, Youbin; Cheng, Xiaomin; Wang, Huaijun; Shi, Zhongtao; Zhao, Junwei; Ji, Fengmin; Yin, Zhi; Wang, Yajuan

    2015-01-01

    Continuous-variable (CV) entanglement frequency comb can be produced by enhanced Raman scattering in an above-threshold optical oscillator cavity in which a hexagonally-poled LiTaO3 crystal resides as a Raman gain medium. The Stokes and anti-Stokes Raman signals are enhanced by a coupled quasi-phase-matching optical parametric process and the entanglement natures among these Raman signals and pump are demonstrated by applying a sufficient inseparability criterion for CV entanglement. Such entanglement frequency comb source with different frequencies and continuously tunable frequency interval may be very significant for the applications in quantum communication and networks. PMID:25600617

  3. Microstructural properties of {InAs}/{InAsxSb1 - x} superlattices and InAs xSb 1 - x ordered alloys grown by modulated molecular beam epitaxy

    NASA Astrophysics Data System (ADS)

    Zhang, Y.-H.; Lew, A.; Yu, E.; Chen, Y.

    1997-05-01

    Modulated molecular beam epitaxy (MMBE) has been demonstrated to be useful in controlling group-V alloys such as InAs xSb 1 - x and AlAs xSb 1 - x. Further studies of the MMBE grown InAs xSb 1 - x ordered alloys and {InAs}/{InAsxSb1 - x} superlattices by using cross-sectional scanning tunneling microscopy show well defined interfaces between InAs xSb 1 - x ordered alloys and InAs. Clear composition modulation is observed in the InAs xSb 1 - x ordered alloy layers. Transmission electron diffraction and microscopy, X-ray diffraction, and low temperature photoluminescence experiments show no obvious sign of CuPt orderings. These results suggest that MMBE provides a possible means to bypass the ordering problem of InAs xSb 1 - x random alloys.

  4. Hair breakage during combing. III. The effects of bleaching and conditioning on short and long segment breakage by wet and dry combing of tresses.

    PubMed

    Robbins, Clarence; Kamath, Yash

    2007-01-01

    A recent publication (1), provided evidence for two types of hair breakage during combing, short segment breakage (approximately less than 1.27 cm) and longer segment breakage. We have confirmed these results and refined the separation distance between short and long segment breakage at about 2.54 cm. Furthermore, chemical bleaching increased both short and long segment breakage while a commercial hair conditioner decreased both types of breakage. Whether the hair is chemically bleached or conditioned, for dry combing, short segment breakage increases with increasing comb strokes, that is, short segment breakage increases as combing damages the ends of the hair, however, long segment breakage does not increase with increasing comb strokes. Wet combing provided a decrease in short segment breakage and an increase in long segment breaks, but no increase in breakage with increasing comb strokes. Mechanical combing of tresses shows similar results qualitatively, however the variance was too large and adjustments need to be made to provide for a larger number of broken hairs to bring the mechanical and hand combing results in line. For dry combing, as the comb descends through the hair, hairs above it are made parallel and those beneath are either made parallel or knot by, hairs looping around other hairs or hairs looping around comb teeth and other hairs several cm between the comb and the hair tips. As the comb advances through the looped/knotted hairs long breaks occur or as the comb descends near the tips wrapped ends can result. End wrapping by inertia & possibly static charge produces short segment breaks which are more severe if the hair is cut at 90 degrees versus a tapered cut. For wet combing, clumping of hairs by a capillary action produces fewer short segment breaks, by reducing end wrapping: however, crossed hair interactions occur & because of higher friction more severe snags arise higher up in the tress, and lower hair breaking load due to plasticization by water, producing a larger number of long segment breaks. The very best practical way to evaluate hair strength is by counting the actual number of short and long segment breaks and by considering both wet and dry combing. PMID:17728947

  5. Spectrum and dynamics of optical frequency combs generated with monolithic whispering gallery mode resonators.

    PubMed

    Chembo, Yanne K; Strekalov, Dmitry V; Yu, Nan

    2010-03-12

    Optical frequency comb generation in whispering gallery mode resonators has been demonstrated in several experiments. The spectra of the combs exhibit a wide variety of complex profiles that are not fully understood. We report a detailed study on frequency comb generation in whispering gallery mode resonators including a complete stability analysis and numerical simulations. We show that the interaction of dispersion and nonlinearity is the key in determining the stability of the comb, the complex characteristics of its spectral profile, and its frequency span. The results will be important for understanding the essential physical processes leading to efficient comb generation. PMID:20366426

  6. A stable frequency comb directly referenced to rubidium electromagnetically induced transparency and two-photon transitions

    SciTech Connect

    Hou, Dong; Wu, Jiutao; Zhang, Shuangyou; Ren, Quansheng; Zhang, Zhigang; Zhao, Jianye

    2014-03-17

    We demonstrate an approach to create a stable erbium-fiber-based frequency comb at communication band by directly locking the combs to two rubidium atomic transitions resonances (electromagnetically induced transparency absorption and two-photon absorption), respectively. This approach directly transfers the precision and stability of the atomic transitions to the comb. With its distinguishing feature of compactness by removing the conventional octave-spanning spectrum and f-to-2f beating facilities and the ability to directly control the comb's frequency at the atomic transition frequency, this stable optical comb can be widely used in optical communication, frequency standard, and optical spectroscopy and microscopy.

  7. Spectral and temporal characterization of a fused-quartz-microresonator optical frequency comb

    SciTech Connect

    Papp, Scott B.; Diddams, Scott A.

    2011-11-15

    We report on the fabrication of high-Q, fused-quartz microresonators and the parametric generation of a frequency comb with 36-GHz line spacing using them. We have characterized the intrinsic stability of the comb in both the time and frequency domains to assess its suitability for future precision metrology applications. Intensity autocorrelation measurements and line-by-line comb control reveal near-transform-limited picosecond pulse trains that are associated with good relative phase and amplitude stability of the comb lines. The comb's 36-GHz line spacing can be readily photodetected, which enables measurements of its intrinsic and absolute phase fluctuations.

  8. Progress with a green astro-comb for exoplanet searches

    NASA Astrophysics Data System (ADS)

    Li, Chih-Hao; Glenday, Alexander G.; Phillips, David F.; Langellier, Nicholas; Chang, Guoqing; Furesz, Gabor; Kaertner, Franz X.; Sasselov, Dimitar; Szentgyorgyi, Andrew; Walsworth, Ronald L.

    2015-05-01

    Searches for extrasolar planets using the precision stellar radial velocity (RV) measurement technique are approaching Earth-like planet sensitivity. Astro-combs, which consist of a laser frequency comb, coherent wavelength shifting mechanism (such as a doubling crystal and photonic crystal fiber), and a mode-filtering Fabry-Perot cavity (FPC), provide a promising route to increased accuracy and long-term stability on the astrophysical spectrograph calibration. We first present the design of a green astro-comb from an octave spanning Ti:Sapphire laser, spectrally broadened by custom tapered PCF to the visible band via fiber-optic Cherenkov radiation for frequency shifting, and filtered by a broadband FPC, constructed by a pair of complementary chirped mirrors. We also present results from two years of operation of the astro-comb calibrating the HARPS-N spectrograph at the Italian National Telescope on La Palma, Canary Islands, including its use in measurements of solar radial velocities as well as its use in searches for extrasolar planets.

  9. Threshold conditions and bands in attractive Dirac comb

    NASA Astrophysics Data System (ADS)

    Dharani, M.; Shastry, C. S.

    2015-06-01

    Taking into account the threshold conditions for the generation of bound states by an attractive delta comb in one dimension, we describe the band structure generated by the same when confined to a box demonstrating the correlation between the potential strength, band width and band gap.

  10. Invited Article: A compact optically coherent fiber frequency comb

    NASA Astrophysics Data System (ADS)

    Sinclair, L. C.; Deschênes, J.-D.; Sonderhouse, L.; Swann, W. C.; Khader, I. H.; Baumann, E.; Newbury, N. R.; Coddington, I.

    2015-08-01

    We describe the design, fabrication, and performance of a self-referenced, optically coherent frequency comb. The system robustness is derived from a combination of an optics package based on polarization-maintaining fiber, saturable absorbers for mode-locking, high signal-to-noise ratio (SNR) detection of the control signals, and digital feedback control for frequency stabilization. The output is phase-coherent over a 1-2 μm octave-spanning spectrum with a pulse repetition rate of ˜200 MHz and a residual pulse-to-pulse timing jitter <3 fs well within the requirements of most frequency-comb applications. Digital control enables phase coherent operation for over 90 h, critical for phase-sensitive applications such as timekeeping. We show that this phase-slip free operation follows the fundamental limit set by the SNR of the control signals. Performance metrics from three nearly identical combs are presented. This laptop-sized comb should enable a wide-range of applications beyond the laboratory.

  11. Astro-Comb Revolutionizing Precision Spectroscopy in Astrophysics

    NASA Astrophysics Data System (ADS)

    Cramer, C. E.; Li, C.-H.; Glenday, A. G.; Phillips, D. F.; Furesz, G.; Sasselov, D.; Szentgyorgyi, A.; Walsworth, R. L.; Benedick, A.; Kärtner, F. X.

    2009-04-01

    Precision Doppler spectroscopy in astrophysics is limited by the stability of calibration sources, as well as the number, width and distribution of available calibration lines. Broadband frequency combs generated from mode-locked femtosecond lasers have revolutionized precision laboratory spectroscopy. We present a laser comb with up to 40 GHz line-spacing, generated from a 1 GHz repetition-rate "source comb" and a Fabry-Perot filtering cavity. The line spacing can be optimized for use with any high-resolution astronomical spectrograph. Our prototype, which we have recently tested with the Tillinghast Reflector Echelle Spectrograph on Mt. Hopkins, provides a 100-nm band of calibration light centered on 850 nm, in the center of the a region difficult to calibrate with atomic sources. The astro-comb should allow more than an order-of-magnitude improvement in sensitivity to changes in Doppler-shifts and cosmological redshifts, with significant impact on many fields, including stellar seismology, cosmology, and the search for extrasolar earths.

  12. Paleontology: a cock's comb on a duck-billed dinosaur.

    PubMed

    Horner, John R

    2014-01-20

    A soft tissue structure has been discovered on the head of the duck-billed dinosaur Edmontosaurus. Its similarity to a cock's comb and other sexually dimorphic structures of birds suggests that potential sexual signals existed in these extinct animals. PMID:24456984

  13. Active laser ranging with frequency transfer using frequency comb

    NASA Astrophysics Data System (ADS)

    Zhang, Hongyuan; Wei, Haoyun; Yang, Honglei; Li, Yan

    2016-05-01

    A comb-based active laser ranging scheme is proposed for enhanced distance resolution and a common time standard for the entire system. Three frequency combs with different repetition rates are used as light sources at the two ends where the distance is measured. Pulse positions are determined through asynchronous optical sampling and type II second harmonic generation. Results show that the system achieves a maximum residual of 379.6 nm and a standard deviation of 92.9 nm with 2000 averages over 23.6 m. Moreover, as for the frequency transfer, an atom clock and an adjustable signal generator, synchronized to the atom clock, are used as time standards for the two ends to appraise the frequency deviation introduced by the proposed system. The system achieves a residual fractional deviation of 1.3 × 10-16 for 1 s, allowing precise frequency transfer between the two clocks at the two ends.

  14. Optical Frequency Comb Spectroscopy of Rare Earth Atoms

    NASA Astrophysics Data System (ADS)

    Swiatlowski, Jerlyn; Palm, Christopher; Joshi, Trinity; Montcrieffe, Caitlin; Jackson Kimball, Derek

    2013-05-01

    We discuss progress in our experimental program to employ optical-frequency-comb-based spectroscopy to understand the complex spectra of rare-earth atoms. We plan to carry out systematic measurements of atomic transitions in rare-earth atoms to elucidate the energy level structure and term assignment and determine presently unknown atomic state parameters. This spectroscopic information is important in view of the increasing interest in rare-earth atoms for atomic frequency standards, in astrophysical investigations of chemically peculiar stars, and in tests of fundamental physics (tests of parity and time-reversal invariance, searches for time variation of fundamental constants, etc.). We are presently studying the use of hollow cathode lamps as atomic sources for two-photon frequency comb spectroscopy. Supported by the National Science Foundation under grant PHY-0958749.

  15. Interferometric homogeneity test using adaptive frequency comb illumination.

    PubMed

    Mantel, Klaus; Schwider, Johannes

    2013-03-20

    The homogeneity test of glass plates in a Fizeau interferometer requires the measurement of the glass sample in reflected as well as in transmitted light. For the measurement in transmitted light, the sample has to be inserted into the ray path of a Fizeau or Twyman-Green interferometer, which leads to a nested cavity setup. To separate the interference signals from the different cavities, we illuminate a Fizeau interferometer with an adaptive frequency comb. In this way, rigid glass plates can be measured, and linear variations in the homogeneity can also be detected. The adaptive frequency comb is provided by a variable Fabry-Perot filter under broadband illumination from a superluminescence diode. Compared to approaches using a two-beam interferometer as a filter for the broadband light source, the visibility of the fringe system is considerably higher. PMID:23518735

  16. Envelope, group and phase velocities in a nested frequency comb

    NASA Astrophysics Data System (ADS)

    Masuda, Koji; Hendrie, James; Diels, Jean-Claude; Arissian, Ladan

    2016-04-01

    Fabry–Pérot etalons have been traditionally used in a laser cavity to tune the optical frequency. In this work we present the generation of interwoven frequency combs with insertion of an intracavity Fabry–Pérot in a mode-locked laser. A high frequency comb is generated by insertion of an uncoated (low finesse) Fabry–Pérot inside the laser cavity. The intracavity Fabry–Pérot acquires a high finesse from the laser cavity and the velocity of the pulses in the Fabry–Pérot is affected by the laser cavity length, gain and losses, with the dielectric group velocity dk/dΩ playing only a minor role. The output characteristics are explained by the condition that the radiation is simultaneously resonant with the etalon and the laser cavity.

  17. Envelope, group and phase velocities in a nested frequency comb

    NASA Astrophysics Data System (ADS)

    Masuda, Koji; Hendrie, James; Diels, Jean-Claude; Arissian, Ladan

    2016-05-01

    Fabry–Pérot etalons have been traditionally used in a laser cavity to tune the optical frequency. In this work we present the generation of interwoven frequency combs with insertion of an intracavity Fabry–Pérot in a mode-locked laser. A high frequency comb is generated by insertion of an uncoated (low finesse) Fabry–Pérot inside the laser cavity. The intracavity Fabry–Pérot acquires a high finesse from the laser cavity and the velocity of the pulses in the Fabry–Pérot is affected by the laser cavity length, gain and losses, with the dielectric group velocity dk/dΩ playing only a minor role. The output characteristics are explained by the condition that the radiation is simultaneously resonant with the etalon and the laser cavity.

  18. A Novel Nit Comb Concept Using Ultrasound Actuation: Preclinical Evaluation.

    PubMed

    Burgess, Mark N; Brunton, Elizabeth R; Burgess, Ian F

    2016-01-01

    Nit combing and removal of head louse, Pediculus humanus capitis De Geer (Anoplura: Pediculidae), eggs is a task made more difficult because "nit combs" vary in efficiency. There is currently no evidence that the binding of the eggshell to the hair can be loosened chemically and few hair treatments improve the slip of the louse eggs along the hair. Ultrasound, applied through the teeth of a nit comb, may facilitate the flow of fluids into the gap between the hair shaft and the tube of fixative holding louse eggs in place to improve lubrication. Ultrasound alone had little effect to initiate sliding, requiring a force of 121.5 ± 23.8 millinewtons (mN) compared with 125.8 ± 18.0 mN without ultrasound, but once the egg started to move it made the process easier. In the presence of a conditioner-like creamy lotion, ultrasound reduced the Peak force required to start movement to 24.3 ± 8.8 mN from 50.4 ± 13.0 mN without ultrasound. In contrast, some head louse treatments made removal of eggs more difficult, requiring approximately twice the Peak force to initiate movement compared with dry hair in the absence of ultrasound. However, following application of ultrasound, the forces required to initiate movement increased for an essential oil product, remained the same for isopropyl myristate and cyclomethicone, and halved for 4% dimeticone lotion. Fixing the nit comb at an estimated angle of 16.5° to the direction of pull gave an optimum effect to improve the removal process when a suitable lubricant was used. PMID:26545717

  19. Generation of a frequency comb and applications thereof

    SciTech Connect

    Hagmann, Mark J; Yarotski, Dmitry A

    2013-12-03

    Apparatus for generating a microwave frequency comb (MFC) in the DC tunneling current of a scanning tunneling microscope (STM) by fast optical rectification, cause by nonlinearity of the DC current vs. voltage curve for the tunneling junction, of regularly-spaced, short pulses of optical radiation from a focused mode-locked, ultrafast laser, directed onto the tunneling junction, is described. Application of the MFC to high resolution dopant profiling in semiconductors is simulated. Application of the MFC to other measurements is described.

  20. Comb-locked cavity ring-down spectrometer

    NASA Astrophysics Data System (ADS)

    Gatti, Davide; Sala, Tommaso; Gotti, Riccardo; Cocola, Lorenzo; Poletto, Luca; Prevedelli, Marco; Laporta, Paolo; Marangoni, Marco

    2015-02-01

    Extreme frequency accuracy and high sensitivity are obtained with a novel comb-locked cavity-ring-down spectrometer operating in the near-infrared from 1.5 to 1.63 μm. A key feature of our approach is the tight frequency locking of the probe laser to the comb, ensuring very high reproducibility and accuracy to the frequency axis upon scanning the comb repetition rate, as well as an efficient light injection into a length-swept high-finesse passive cavity containing the gas sample. Spectroscopic tests on the (30012) ← (00001) P14e line of CO2 at ˜1.57 μm demonstrate an accuracy of ˜17 kHz on the line center frequency in a Doppler broadening regime over the time scale of about 5 min, corresponding to four consecutive spectral scans of the absorption line. Over a single scan, which consists of 1500 spectral points over 75 s, the limit of detection is as low as 5.7 × 10-11 cm-1.

  1. Coherent Raman spectro-imaging with laser frequency combs.

    PubMed

    Ideguchi, Takuro; Holzner, Simon; Bernhardt, Birgitta; Guelachvili, Guy; Picqué, Nathalie; Hänsch, Theodor W

    2013-10-17

    Advances in optical spectroscopy and microscopy have had a profound impact throughout the physical, chemical and biological sciences. One example is coherent Raman spectroscopy, a versatile technique interrogating vibrational transitions in molecules. It offers high spatial resolution and three-dimensional sectioning capabilities that make it a label-free tool for the non-destructive and chemically selective probing of complex systems. Indeed, single-colour Raman bands have been imaged in biological tissue at video rates by using ultra-short-pulse lasers. However, identifying multiple, and possibly unknown, molecules requires broad spectral bandwidth and high resolution. Moderate spectral spans combined with high-speed acquisition are now within reach using multichannel detection or frequency-swept laser beams. Laser frequency combs are finding increasing use for broadband molecular linear absorption spectroscopy. Here we show, by exploring their potential for nonlinear spectroscopy, that they can be harnessed for coherent anti-Stokes Raman spectroscopy and spectro-imaging. The method uses two combs and can simultaneously measure, on the microsecond timescale, all spectral elements over a wide bandwidth and with high resolution on a single photodetector. Although the overall measurement time in our proof-of-principle experiments is limited by the waiting times between successive spectral acquisitions, this limitation can be overcome with further system development. We therefore expect that our approach of using laser frequency combs will not only enable new applications for nonlinear microscopy but also benefit other nonlinear spectroscopic techniques. PMID:24132293

  2. Dual-Colored DNA Comb Polymers for Single Molecule Rheology

    NASA Astrophysics Data System (ADS)

    Mai, Danielle; Marciel, Amanda; Schroeder, Charles

    2014-03-01

    We report the synthesis and characterization of branched biopolymers for single molecule rheology. In our work, we utilize a hybrid enzymatic-synthetic approach to graft ``short'' DNA branches to ``long'' DNA backbones, thereby producing macromolecular DNA comb polymers. The branches and backbones are synthesized via polymerase chain reaction with chemically modified deoxyribonucleotides (dNTPs): ``short'' branches consist of Cy5-labeled dNTPs and a terminal azide group, and ``long'' backbones contain dibenzylcyclooctyne-modified (DBCO) dNTPs. In this way, we utilize strain-promoted, copper-free cycloaddition ``click'' reactions for facile grafting of azide-terminated branches at DBCO sites along backbones. Copper-free click reactions are bio-orthogonal and nearly quantitative when carried out under mild conditions. Moreover, comb polymers can be labeled with an intercalating dye (e.g., YOYO) for dual-color fluorescence imaging. We characterized these materials using gel electrophoresis, HPLC, and optical microscopy, with atomic force microscopy in progress. Overall, DNA combs are suitable for single molecule dynamics, and in this way, our work holds the potential to improve our understanding of topologically complex polymer melts and solutions.

  3. Direct fiber comb stabilization to a gas-filled hollow-core photonic crystal fiber.

    PubMed

    Wu, Shun; Wang, Chenchen; Fourcade-Dutin, Coralie; Washburn, Brian R; Benabid, Fetah; Corwin, Kristan L

    2014-09-22

    We have isolated a single tooth from a fiber laser-based optical frequency comb for nonlinear spectroscopy and thereby directly referenced the comb. An 89 MHz erbium fiber laser frequency comb is directly stabilized to the P(23) (1539.43 nm) overtone transition of (12)C(2)H(2) inside a hollow-core photonic crystal fiber. To do this, a single comb tooth is isolated and amplified from 20 nW to 40 mW with sufficient fidelity to perform saturated absorption spectroscopy. The fractional stability of the comb, ~7 nm away from the stabilized tooth, is shown to be 6 × 10(-12) at 100 ms gate time, which is over an order of magnitude better than that of a comb referenced to a GPS-disciplined Rb oscillator. PMID:25321837

  4. Solar oscillations and the search for Venus enabled by a laser frequency comb

    NASA Astrophysics Data System (ADS)

    Phillips, David F.; Glenday, Alexander G.; Li, Chih-Hao; Langellier, Nicholas; Chang, Guoqing; Furesz, Gabor; Kaertner, Franz X.; Sasselov, Dimitar; Szentgyorgyi, Andrew; Walsworth, Ronald L.

    2015-05-01

    We have recently demonstrated sub-m/s sensitivity in measuring the radial velocity (RV) between the Earth and Sun using a simple, home-built solar telescope feeding the HARPS-N spectrograph at the Italian National Telescope calibrated with our green astro-comb. The green astro-comb is a laser frequency comb optimized for calibrating astrophysical spectrographs. We plan, in the coming year, to use the astro-comb calibrated spectrograph and solar telescope to detect the solar RV signal induced by Venus and thus demonstrate sensitivity of these instruments to detect terrestrial exoplanets. Here, we will present the astro-comb, results from the astro-comb calibrating the HARPS-N exoplanet searcher spectrograph, solar RV stability and plans for observing the signature of Venus.

  5. [Gender, medicine and consumer culture: the cultural history of comb in the Ming and Qing Dynasties].

    PubMed

    Chen, Siyan

    2014-09-01

    In the Ming and Qing Dynasties, in addition to combing the hair, the comb also gradually played a role in people's daily life for disease treatment and keeping people's health. In short, during this period, the characteristic of comb reveal, as a whole, its reinforcing practicability and weakening of its ornamentality. During its application, people's behavioral activities endowed the comb with definite cultural connotation, which, thanks to the presence of gender and personality, became the symbol for expressing love between man and woman. By analogizing people's thought, since the comb could dredge something. Therefore, it can be used to cure diseases. Thus, it could be seen that, based on consumer's cultural description, the comb, tiny as it may be, did reflect the aesthetic ideas and interests and daily life-preservation habit of the literati due to the flourishing of book market in the Ming and Qing Dynasties. PMID:25579212

  6. Redescription of Synthesium pontoporiae n. comb. with notes on S. tursionis and S. seymouri n. comb. (Digenea: Brachycladiidae Odhner, 1905).

    PubMed

    Marigo, Juliana; Vicente, Ana Carolina Paulo; Valente, Ana Luisa Schifino; Measures, Lena; Santos, Cláudia Portes

    2008-04-01

    Synthesium pontoporiae n. comb. is redescribed, together with Synthesium tursionis and Synthesium seymouri n. comb.; the parasites were obtained from stranded and accidentally caught cetaceans. The sucker ratio (ratio between widths of the oral and ventral suckers) in S. pontoporiae was 1:1.8-3.0 (mean 1:2.2); in S. tursionis was 1:0.8-1.2; and in S. seymouri was 1:0.5-0.7. Synthesium pontoporiae differed from its congeners by additional diagnostic characters, including: oval to lobed testes; small cirrus with pyriform proximal region and flexible, tubular distal region formed by evagination of ejaculatory duct; and vitellarium in small follicles extending from the level of the seminal vesicle to the posterior extremity of the body and not forming dendritic radial bunches. Data on the morphology of adult S. pontoporiae and S. tursionis were inferred from confocal laser microscopical observations. PMID:18564752

  7. Broadband Mid-Infrared Comb-Resolved Fourier Transform Spectroscopy

    NASA Astrophysics Data System (ADS)

    Lee, Kevin; Mills, Andrew; Mohr, Christian; Jiang, Jie; Fermann, Martin; Maslowski, Piotr

    2014-06-01

    We report on a comb-resolved, broadband, direct-comb spectroscopy system in the mid-IR and its application to the detection of trace gases and molecular line shape analysis. By coupling an optical parametric oscillator (OPO), a 100 m multipass cell, and a high-resolution Fourier transform spectrometer (FTS), sensitive, comb-resolved broadband spectroscopy of dilute gases is possible. The OPO has radiation output at 3.1-3.7 and 4.5-5.5 μm. The laser repetition rate is scanned to arbitrary values with 1 Hz accuracy around 417 MHz. The comb-resolved spectrum is produced with an absolute frequency axis depending only on the RF reference (in this case a GPS disciplined oscillator), stable to 1 part in 10^9. The minimum detectable absorption is 1.6x10-6 wn Hz-1/2. The operating range of the experimental setup enables access to strong fundamental transitions of numerous molecular species for applications based on trace gas detection such as environmental monitoring, industrial gas calibration or medical application of human breath analysis. In addition to these capabilities, we show the application for careful line shape analysis of argon-broadened CO band spectra around 4.7 μm. Fits of the obtained spectra clearly illustrate the discrepancy between the measured spectra and the Voigt profile (VP), indicating the need to include effects such as Dicke narrowing and the speed-dependence of the collisional width and shift in the line shape model, as was shown in previous cw-laser studies. In contrast to cw-laser based experiments, in this case the entire spectrum (˜ 250 wn) covering the whole P and R branches can be measured in 16 s with 417 MHz resolution, decreasing the acquisition time by orders of magnitude. The parallel acquisition allows collection of multiple lines simultaneously, removing the correlation of possible temperature and pressure drifts. While cw-systems are capable of measuring spectra with higher precision, this demonstration opens the door for fast, massively parallel line shape parameters retrieval combined with analysis reaching beyond the VP and with absolute frequency calibration delivered by frequency combs. R. Wehr et al. J. Mol. Spec. 235 54-68 (2003) A. Cygan, et al. Eur. Phys. J. Special Topics 222 2119-2142 (2013)

  8. Sex Stereotyping.

    ERIC Educational Resources Information Center

    Rivas, Richard G.

    This article uses findings from several previous studies to define the kinds of sex stereotyping present in our society. The author considers sex roles as dealt with in children's literature, public schools, advertising, and vocational counseling. He describes, in particular, the situation at an unnamed state university, and cites the woman's…

  9. Effect of a breather soliton in Kerr frequency combs on optical communication systems.

    PubMed

    Bao, Changjing; Liao, Peicheng; Zhang, Lin; Yan, Yan; Cao, Yinwen; Xie, Guodong; Mohajerin-Ariaei, Amirhossein; Li, Long; Ziyadi, Morteza; Almaiman, Ahmed; Kimerling, Lionel C; Michel, Jurgen; Willner, Alan E

    2016-04-15

    In this study, we numerically investigate the effect of Kerr-comb-generated breather soliton pulses on optical communication systems. The breather soliton pulse amplitude and spectrum envelope oscillate periodically in time. Simulations show that the spectrum of each comb line in the breather soliton state has multiple sub-teeth due to the periodic oscillation of the comb spectrum. In the simulation, the comb output is modulated with different formats. We find that the sub-teeth distort quadrature phase-shift-keyed signals but have less of an effect on on-off-keyed signals. PMID:27082339

  10. Damping effects of capacitive comb fingers on biomimetic MEMS directional microphone

    NASA Astrophysics Data System (ADS)

    Roth, John; Touse, Michael; Sinibaldi, Jose; Karunasiri, Gamani

    2011-03-01

    MEMS directional sound sensors that use two coupled wings moving in air are subjected to viscous damping. The amplitude of oscillation of the sensors is read out by measuring the capacitance of interdigitated comb fingers along the edges of the wings. In this presentation, effects of damping on MEMS sensors with and without comb fingers will be described. It was found that the sensors with comb fingers have a significantly larger damping indicating that the longer perimeter due to combs is responsible for the observed increase. However, the increase in damping reduces the quality factor which improves the response time of the device. This work is supported by NSF.

  11. Spectral linewidth preservation in parametric frequency combs seeded by dual pumps.

    PubMed

    Tong, Zhi; Wiberg, Andreas O J; Myslivets, Evgeny; Kuo, Bill P P; Alic, Nikola; Radic, Stojan

    2012-07-30

    We demonstrate new technique for generation of programmable-pitch, wideband frequency combs with low phase noise. The comb generation was achieved using cavity-less, multistage mixer driven by two tunable continuous-wave pump seeds. The approach relies on phase-correlated continuous-wave pumps in order to cancel spectral linewidth broadening inherent to parametric comb generation. Parametric combs with over 200-nm bandwidth were obtained and characterized with respect to phase noise scaling to demonstrate linewidth preservation over 100 generated tones. PMID:23038314

  12. Calibration of an astrophysical spectrograph below 1 m/s using a laser frequency comb.

    PubMed

    Phillips, David F; Glenday, Alexander G; Li, Chih-Hao; Cramer, Claire; Furesz, Gabor; Chang, Guoqing; Benedick, Andrew J; Chen, Li-Jin; Kärtner, Franz X; Korzennik, Sylvain; Sasselov, Dimitar; Szentgyorgyi, Andrew; Walsworth, Ronald L

    2012-06-18

    We deployed two wavelength calibrators based on laser frequency combs ("astro-combs") at an astronomical telescope. One astro-comb operated over a 100 nm band in the deep red (∼ 800 nm) and a second operated over a 20 nm band in the blue (∼ 400 nm). We used these red and blue astro-combs to calibrate a high-resolution astrophysical spectrograph integrated with a 1.5 m telescope, and demonstrated calibration precision and stability sufficient to enable detection of changes in stellar radial velocity < 1 m/s. PMID:22714437

  13. Comb-Referenced Sub-Doppler Resolution Infrared Spectrometer

    NASA Astrophysics Data System (ADS)

    Sasada, Hiroyuki

    2015-06-01

    We have developed a sub-Doppler resolution spectrometer. A difference frequency generation source, which consists of a pump source of a Nd:YAG laser, a signal source of an extended-cavity laser diode, and a waveguide-type PPLN, covers from 87 to 93 THz (2900 to 3100 wn). An enhanced-cavity absorption cell remarkably improves the sensitivity of Lamb dips. An optical frequency comb controls the central frequency of the source with an uncertainty of a few kilohertz. Because the idler frequency is swept based on absolute frequency through the comb, recorded spectra can be repeatedly accumulated without any frequency drift. We have applied the spectrometer to resolve the hyperfine structure of the fundamental band of HCl with a spectral resolution of about 250 kHz. To reduce the transit-time broadening, a novel enhanced-cavity absorption cell coupled with an idler wave of 1.9-mm beam radius at the beam waist has been introduced. The A1-A2 splitting of the νb{1} and νb{4} bands of CH3D is resolved for a few tens low-J transitions with the Lamb-dip linewidth of 60 to 100 kHz. Very recently, the source linewidth has reduced to 3 kHz using a linewidth transfer technique from the Nd:YAG laser to the extended-cavity laser diode through a novel optical frequency comb with a fast servo control. When methane sample is cooled with liquid-nitrogen, and the beam radius is expanded to 3 mm, the observed Lamb dip is 20 kHz wide without any enhanced-cavity absorption cell.

  14. Multiple beam Fizeau interferometer with filtered frequency comb illumination

    NASA Astrophysics Data System (ADS)

    Schwider, J.

    2009-08-01

    Real wedge interferometers of the Fizeau-type do not allow for fringes in case of a spectral broadband source - or in short: for white light fringes. Here, the use of a suitable frequency comb source will help to overcome this limitation on the one hand and on the other will offer the capability for enhanced phase sensitivity in high precision measurements of surface deviations. Frequency combs can be produced either by using a pulse train from a fs-laser or by passive filtering of the light emitted by a broadband source as a superlum-diode or a fs-laser. The frequency comb produced by a common fs-laser is extremely fine, i.e., the frequency difference of consecutive peaks is very small or the distance of consecutive pulses of the pulse train might be of the order of 1 m. Therefore, the pulse train produced by passive filtering of a broadband source is better adapted to the needs of surface testing interferometers. White light fringes are either applied for the profiling of discontinuous surfaces and/or can serve as an indication for the correct choice of multiplication factors in superposition interferometry. During the last decennium it became more and more clear that spatially incoherent sources provide better measuring accuracy in surface measurements due to the reduced influence of dust diffraction patterns. The advantage of laser illumination can nevertheless be maintained if the laser light is made spatially incoherent through moving scatterers in the light path. Here, we will discuss the application of spatially incoherent broadband light frequency filtered through a Fabry-Perot filter. The main applications are in the following fields: (1) surface profiling applications using two-beam Fizeau interferometers, (2) selection of single cavities out of a series of interlaced cavities, and (3) sensitivity enhancement for multi-beam interferometers for planeness or sphericity measurements. Some of the discussed possibilities will be experimentally demonstrated.

  15. Sex Stereotyping.

    ERIC Educational Resources Information Center

    Western European Education, 1982

    1982-01-01

    Presents the Norwegian Ministry of Education's recommendations to the Council of Europe for reforming European education to prevent sex discrimination against women at the elementary and secondary levels. (AM)

  16. The Tribolium castaneum ortholog of Sex combs reduced controls dorsal ridge development

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In insects, the boundary between the embryonic head and thorax is formed by the dorsal ridge, a fused structure composed of portions of the maxillary and labial segments. However, the mechanisms that promote development of this unusual structure remain a mystery. In Drosophila, mutations in the Hox ...

  17. Frequency stabilized optical comb source with high finesse intracavity etalon

    NASA Astrophysics Data System (ADS)

    Ozdur, Ibrahim; Ozharar, Sarper; Akbulut, Mehmetcan; Mandridis, Dimitrios; Quinlan, Franklyn; Delfyett, Peter J.

    2009-05-01

    Mode-locked lasers have applications in signal processing and communications such as analog to digital conversion, arbitrary waveform generation and wavelength division multiplexing. For such applications low noise and phase coherent frequency stabilized optical combs are needed. In this work we report a low noise, Pound-Drever Hall frequency stabilized, semiconductor mode-locked laser at 10.287GHz centered at 1550nm with 1000-Finesse sealed, ultralow insertion loss intracavity etalon. The output optical power of the mode locked laser is ~5mW.

  18. Noninvasive fetal ECG estimation using adaptive comb filter.

    PubMed

    Wei, Zheng; Xueyun, Wei; Jian jian, Zhong; Hongxing, Liu

    2013-10-01

    This paper describes a robust and simple algorithm for fetal electrocardiogram (FECG) estimation from abdominal signal using adaptive comb filter (ACF). The ACF can adjust itself to the temporal variations in fundamental frequency, which makes it qualified for the estimation of quasi-periodic component from physiologic signal, such as ECG. The validity and performance of the described method are confirmed through experiments on real fetal ECG data. A comparison with the well-known independent component analysis (ICA) method has also been presented. PMID:23942332

  19. Frequency combs with weakly lasing exciton-polariton condensates.

    PubMed

    Rayanov, K; Altshuler, B L; Rubo, Y G; Flach, S

    2015-05-15

    We predict the spontaneous modulated emission from a pair of exciton-polariton condensates due to coherent (Josephson) and dissipative coupling. We show that strong polariton-polariton interaction generates complex dynamics in the weak-lasing domain way beyond Hopf bifurcations. As a result, the exciton-polariton condensates exhibit self-induced oscillations and emit an equidistant frequency comb light spectrum. A plethora of possible emission spectra with asymmetric peak distributions appears due to spontaneously broken time-reversal symmetry. The lasing dynamics is affected by the shot noise arising from the influx of polaritons. That results in a complex inhomogeneous line broadening. PMID:26024173

  20. Sub-Lethal Effects of Pesticide Residues in Brood Comb on Worker Honey Bee (Apis mellifera) Development and Longevity

    PubMed Central

    Wu, Judy Y.; Anelli, Carol M.; Sheppard, Walter S.

    2011-01-01

    Background Numerous surveys reveal high levels of pesticide residue contamination in honey bee comb. We conducted studies to examine possible direct and indirect effects of pesticide exposure from contaminated brood comb on developing worker bees and adult worker lifespan. Methodology/Principal Findings Worker bees were reared in brood comb containing high levels of known pesticide residues (treatment) or in relatively uncontaminated brood comb (control). Delayed development was observed in bees reared in treatment combs containing high levels of pesticides particularly in the early stages (day 4 and 8) of worker bee development. Adult longevity was reduced by 4 days in bees exposed to pesticide residues in contaminated brood comb during development. Pesticide residue migration from comb containing high pesticide residues caused contamination of control comb after multiple brood cycles and provided insight on how quickly residues move through wax. Higher brood mortality and delayed adult emergence occurred after multiple brood cycles in contaminated control combs. In contrast, survivability increased in bees reared in treatment comb after multiple brood cycles when pesticide residues had been reduced in treatment combs due to residue migration into uncontaminated control combs, supporting comb replacement efforts. Chemical analysis after the experiment confirmed the migration of pesticide residues from treatment combs into previously uncontaminated control comb. Conclusions/Significance This study is the first to demonstrate sub-lethal effects on worker honey bees from pesticide residue exposure from contaminated brood comb. Sub-lethal effects, including delayed larval development and adult emergence or shortened adult longevity, can have indirect effects on the colony such as premature shifts in hive roles and foraging activity. In addition, longer development time for bees may provide a reproductive advantage for parasitic Varroa destructor mites. The impact of delayed development in bees on Varroa mite fecundity should be examined further. PMID:21373182

  1. All polarization-maintaining Er fiber-based optical frequency combs with nonlinear amplifying loop mirror.

    PubMed

    Kuse, N; Jiang, J; Lee, C-C; Schibli, T R; Fermann, M E

    2016-02-01

    A fully stabilized all polarization-maintaining Er frequency comb with a nonlinear amplifying loop mirror with below 0.2 rad carrier-envelope-offset frequency phase noise is demonstrated. The integrated timing jitter is measured as 40 attosecond from 10 kHz to 10 MHz, which is the lowest value of any Er fiber frequency comb to date. PMID:26906874

  2. Design and Fabrication of Polymer Electrostatic Comb-Drive Actuators for Micro Conveyer Systems

    NASA Astrophysics Data System (ADS)

    Pham, Phuc Hong; Dao, Dzung Viet; Amaya, Satoshi; Kitada, Ryoji; Li, Yigui; Sugiyama, Susumu

    We propose the design, simulation and preliminary fabrication of Micro Conveyer Systems (MCS) based on polymer electrostatic comb-drive actuators using polymethylmethacrylate (PMMA). This MCS consists of linear comb actuators, rotational comb actuators, micro containers, and a ratchet mechanism. Micro containers, used for carrying micro and nano samples such as protein, cells, are moved by comb-actuators through the ratchet mechanism. The silicon MCS was fabricated and checked to confirm characteristics and working principles. Each PMMA MCS, which has dimension of 1x1cm2, will be fabricated by using hot embossing technique or X-ray lithography. A silicon mold has to be fabricated first by using silicon wafer and ICP-RIE process. Salient advantages of PMMA comb-drive actuators are low cost, high throughput and consuming less energy compared with the counterpart using silicon because PMMA has a lower Young's modulus.

  3. Photothermally driven fast responding photo-actuators fabricated with comb-type hydrogels and magnetite nanoparticles

    NASA Astrophysics Data System (ADS)

    Lee, Eunsu; Kim, Dowan; Kim, Haneul; Yoon, Jinhwan

    2015-10-01

    To overcome the slow kinetics of the volume phase transition of stimuli-responsive hydrogels as platforms for soft actuators, thermally responsive comb-type hydrogels were prepared using synthesized poly(N-isopropylacrylamide) macromonomers bearing graft chains. Fast responding light-responsive hydrogels were fabricated by combining a comb-type hydrogel matrix with photothermal magnetite nanoparticles (MNP). The MNPs dispersed in the matrix provide heat to stimulate the volume change of the hydrogel matrix by converting absorbed visible light to thermal energy. In this process, the comb-type hydrogel matrix exhibited a rapid response due to the free, mobile grafted chains. The comb-type hydrogel exhibited significantly enhanced light-induced volume shrinkage and rapid recovery. The comb-type hydrogels containing MNP were successfully used to fabricate a bilayer-type photo-actuator with fast bending motion.

  4. Photothermally driven fast responding photo-actuators fabricated with comb-type hydrogels and magnetite nanoparticles

    PubMed Central

    Lee, Eunsu; Kim, Dowan; Kim, Haneul; Yoon, Jinhwan

    2015-01-01

    To overcome the slow kinetics of the volume phase transition of stimuli-responsive hydrogels as platforms for soft actuators, thermally responsive comb-type hydrogels were prepared using synthesized poly(N-isopropylacrylamide) macromonomers bearing graft chains. Fast responding light-responsive hydrogels were fabricated by combining a comb-type hydrogel matrix with photothermal magnetite nanoparticles (MNP). The MNPs dispersed in the matrix provide heat to stimulate the volume change of the hydrogel matrix by converting absorbed visible light to thermal energy. In this process, the comb-type hydrogel matrix exhibited a rapid response due to the free, mobile grafted chains. The comb-type hydrogel exhibited significantly enhanced light-induced volume shrinkage and rapid recovery. The comb-type hydrogels containing MNP were successfully used to fabricate a bilayer-type photo-actuator with fast bending motion. PMID:26459918

  5. Characterization of a DFG comb showing quadratic scaling of the phase noise with frequency.

    PubMed

    Puppe, Thomas; Sell, Alexander; Kliese, Russell; Hoghooghi, Nazanin; Zach, Armin; Kaenders, Wilhelm

    2016-04-15

    We characterize an Er:fiber laser frequency comb that is passively carrier envelope phase-stabilized via difference frequency generation at a wavelength of 1550 nm. A generic method to measure the comb linewidth at different wavelengths is demonstrated. By transferring the properties of a comb line to a cw external cavity diode laser, the phase noise is subsequently measured by tracking the delayed self-heterodyne beat note. This relatively simple characterization method is suitable for a broad range of optical frequencies. Here, it is used to characterize our difference frequency generation (DFG) comb over nearly an optical octave. With repetition-rate stabilization, a radiofrequency reference oscillator limited linewidth is achieved. A lock to an optical reference shows out-of-loop linewidths of the comb at the hertz level. The phase noise measurements are in excellent agreement with the elastic tape model with a fix point at zero frequency. PMID:27082368

  6. 75 FR 11559 - Certain Combed Cotton Yarns: Effect of Modification of U.S.-Bahrain FTA Rules of Origin

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-11

    ... COMMISSION Certain Combed Cotton Yarns: Effect of Modification of U.S.- Bahrain FTA Rules of Origin AGENCY...-103-025, Certain Combed Cotton Yarns: Effect of Modification of U.S.-Bahrain FTA Rules Of Origin... government of Bahrain on certain modifications to the rules of origin to the FTA for certain combed...

  7. Molecular combing compared to Southern blot for measuring D4Z4 contractions in FSHD.

    PubMed

    Vasale, Jessica; Boyar, Fatih; Jocson, Michael; Sulcova, Vladimira; Chan, Patricia; Liaquat, Khalida; Hoffman, Carol; Meservey, Marc; Chang, Isabell; Tsao, David; Hensley, Kerri; Liu, Yan; Owen, Renius; Braastad, Corey; Sun, Weimin; Walrafen, Pierre; Komatsu, Jun; Wang, Jia-Chi; Bensimon, Aaron; Anguiano, Arturo; Jaremko, Malgorzata; Wang, Zhenyuan; Batish, Sat; Strom, Charles; Higgins, Joseph

    2015-12-01

    We compare molecular combing to Southern blot in the analysis of the facioscapulohumeral muscular dystrophy type 1 locus (FSHD1) on chromosome 4q35-qter (chr 4q) in genomic DNA specimens sent to a clinical laboratory for FSHD testing. A de-identified set of 87 genomic DNA specimens determined by Southern blot as normal (n = 71), abnormal with D4Z4 macrosatellite repeat array contractions (n = 7), indeterminate (n = 6), borderline (n = 2), or mosaic (n = 1) was independently re-analyzed by molecular combing in a blinded fashion. The molecular combing results were identical to the Southern blot results in 75 (86%) of cases. All contractions (n = 7) and mosaics (n = 1) detected by Southern blot were confirmed by molecular combing. Of the 71 samples with normal Southern blot results, 67 (94%) had concordant molecular combing results. The four discrepancies were either mosaic (n = 2), rearranged (n = 1), or borderline by molecular combing (n = 1). All indeterminate Southern blot results (n = 6) were resolved by molecular combing as either normal (n = 4), borderline (n = 1), or rearranged (n = 1). The two borderline Southern blot results showed a D4Z4 contraction on the chr 4qA allele and a normal result by molecular combing. Molecular combing overcomes a number of technical limitations of Southern blot by providing direct visualization of D4Z4 macrosatellite repeat arrays on specific chr 4q and chr 10q alleles and more precise D4Z4 repeat sizing. This study suggests that molecular combing has superior analytical validity compared to Southern blot for determining D4Z4 contraction size, detecting mosaicism, and resolving borderline and indeterminate Southern blot results. Further studies are needed to establish the clinical validity and diagnostic accuracy of these findings in FSHD. PMID:26420234

  8. A Fine-Tooth Comb to Measure the Accelerating Universe

    NASA Astrophysics Data System (ADS)

    2008-09-01

    Astronomical instruments needed to answer crucial questions, such as the search for Earth-like planets or the way the Universe expands, have come a step closer with the first demonstration at the telescope of a new calibration system for precise spectrographs. The method uses a Nobel Prize-winning technology called a 'laser frequency comb', and is published in this week's issue of Science. Uncovering the disc ESO PR Photo 26a/08 A Laser Comb for Astronomy "It looks as if we are on the way to fulfil one of astronomers' dreams," says team member Theodor Hänsch, director at the Max Planck Institute for Quantum Optics (MPQ) in Germany. Hänsch, together with John Hall, was awarded the 2005 Nobel Prize in Physics for work including the frequency comb technique. Astronomers use instruments called spectrographs to spread the light from celestial objects into its component colours, or frequencies, in the same way water droplets create a rainbow from sunlight. They can then measure the velocities of stars, galaxies and quasars, search for planets around other stars, or study the expansion of the Universe. A spectrograph must be accurately calibrated so that the frequencies of light can be correctly measured. This is similar to how we need accurate rulers to measure lengths correctly. In the present case, a laser provides a sort of ruler, for measuring colours rather than distances, with an extremely accurate and fine grid. New, extremely precise spectrographs will be needed in experiments planned for the future European Extremely Large Telescope (E-ELT), which is being designed by ESO, the European Southern Observatory. These new spectrographs will need to be calibrated with even more accurate 'rulers'. In fact, they must be accurate to about one part in 30 billions - a feat equivalent to measuring the circumference of the Earth to about a millimetre! "We'll need something beyond what current technology can offer, and that's where the laser frequency comb comes in. It is worth recalling that the kind of precision required, 1 cm/s, corresponds, on the focal plane of a typical high-resolution spectrograph, to a shift of a few tenths of a nanometre, that is, the size of some molecules," explains PhD student and team member Constanza Araujo-Hauck from ESO. The new calibration technique comes from the combination of astronomy and quantum optics, in a collaboration between researchers at ESO and the Max Planck Institute for Quantum Optics. It uses ultra-short pulses of laser light to create a 'frequency comb' - light at many frequencies separated by a constant interval - to create just the kind of precise 'ruler' needed to calibrate a spectrograph. After successful tests in the MPQ laboratory in 2007, the team have successfully tested a prototype device using the laser comb at the VTT (Vacuum Tower Telescope) solar telescope in Tenerife, on 8 March 2008, measuring the spectrum of the Sun in infrared light. The results are already impressive, and the technique promises to achieve the accuracy needed to study these big astronomical questions. "In our tests in Tenerife, we have already achieved beyond state-of-the-art accuracy. Now we are going to make the system more versatile, and develop it even further," says team member Tilo Steinmetz, from Menlo Systems GmbH, a spin-off company from the Max Planck Institute, which was founded to commercialise the frequency comb technique. Having tested the technique on a solar telescope, a new version of the system is now being built for the HARPS planet-finder instrument on ESO's 3.6-metre telescope at La Silla in Chile, before being considered for future generations of instruments. One of the ambitious project to be realised with the E-ELT, called CODEX, aims to measure the recently discovered acceleration of the universe directly, by following the velocities of distant galaxies and quasars over a 20-year period. This would let astronomers test Einstein's general relativity and the nature of the recently discovered, and mysterious, dark energy. "We have to measure the movement of these distant galaxies to a few centimetres per second, and follow this over decades. These speeds are barely faster than a snail's pace, and the laser frequency comb is absolutely crucial for this," says team member Antonio Manescau, from ESO. Astronomers also use spectrographs to hunt for planets around other stars, by watching for subtle movements of the star as the planet orbits it. To be detected with current technology, these planets must be relatively massive or close to the star, compared to Earth. A more precise spectrograph will let astronomers find planets, with characteristics similar to Earth's.

  9. A Study of the Effect of the Fringe Fields on the Electrostatic Force in Vertical Comb Drives

    PubMed Central

    Gallagher, Else; Moussa, Walied

    2014-01-01

    The equation that describes the relationship between the applied voltage and the resulting electrostatic force within comb drives is often used to assist in choosing the dimensions for their design. This paper re-examines how some of these dimensions—particularly the cross-sectional dimensions of the comb teeth—affect this relationship in vertical comb drives. The electrostatic forces in several vertical comb drives fabricated for this study were measured and compared to predictions made with four different mathematical models in order to explore the amount of complexity required within a model to accurately predict the electrostatic forces in the comb drives. PMID:25350504

  10. Evaluation of distributed-type inorganic electroluminescence devices using comb-shaped electrodes

    NASA Astrophysics Data System (ADS)

    Nonaka, Toshihiro; Uraoka, Yukiharu; Taguchi, Nobuyoshi; Yamamoto, Shin-ichi

    2015-03-01

    We deposited comb-shaped metal electrodes with narrow gaps on a glass substrate and succeeded in achieving a high electric field intensity. Using conventional structures, this result could only be achieved by applying transparent electrodes, and in this study, we used a comb-shaped metal (Au) electrode and a comb-shaped indium tin oxide (ITO) electrode. When we measured the luminescence from the opposite side of the comb-shaped electrodes, at 15 V/µm, the luminance in the ITO electrode sample was identical (92-95 cd/m2) to that measured from the side of the comb-shaped electrodes. Conversely, a 111-cd/m2 brightness (a 1.9-fold increase) was observed from the opposite side of the Au electrode. Electrode transmittance was unnecessary when the luminescence was observed from the opposite side of the comb-shaped electrodes, and by using metals such as Au, it was possible to produce a display that did not require transparent electrodes. Finally, we simulated the electric field distribution for the inorganic electroluminescence (EL) using comb-shaped electrodes by semiconductor device simulator Atlas.

  11. Terabit/s communications using chip-scale frequency comb sources

    NASA Astrophysics Data System (ADS)

    Koos, Christian; Kippenberg, Tobias J.; Barry, Liam P.; Dalton, Larry; Freude, Wolfgang; Leuthold, Juerg; Pfeifle, Joerg; Weimann, Claudius; Lauermann, Matthias; Kemal, Juned N.; Palmer, Robert; Koeber, Sebastian; Schindler, Philipp C.; Herr, Tobias; Brasch, Victor; Watts, Regan T.; Elder, Delwin

    2015-03-01

    High-speed optical interconnects rely on advanced wavelength-division multiplexing (WDM) schemes. However, while photonic-electronic interfaces can be efficiently realized on silicon-on-insulator chips, dense integration of the necessary light sources still represents a major challenge. Chip-scale frequency comb sources present an attractive alternative for providing a multitude of optical carriers for WDM transmission. In this paper, we give an overview of our recent progress towards terabit communications with chip-scale frequency comb sources. In a first set of experiments, we demonstrate frequency comb generation based on silicon-organic hybrid (SOH) electro-optic modulators, enabling line rates up to 1.152 Tbit/s. In a second set of experiments, we use injection locking of a gain-switched laser diode to enerate frequency combs. This approach leads to line rates of more than 2 Tbit/s. A third set of experiments is finally dedicated to using Kerr nonlinearities in integrated nonlinear microcavities for frequency comb generation. We demonstrate coherent communication using Kerr frequency comb sources, thereby achieving line rates up to 1.44 Tbit/s. Our experiments show that frequency comb generation in chip-scale devices represents a viable approach to terabit communications.

  12. Noise-Immune Cavity-Enhanced Optical Frequency Comb Spectroscopy

    NASA Astrophysics Data System (ADS)

    Rutkowski, Lucile; Khodabakhsh, Amir; Johanssson, Alexandra C.; Foltynowicz, Aleksandra

    2015-06-01

    We present noise-immune cavity-enhanced optical frequency comb spectroscopy (NICE-OFCS), a recently developed technique for sensitive, broadband, and high resolution spectroscopy. In NICE-OFCS an optical frequency comb (OFC) is locked to a high finesse cavity and phase-modulated at a frequency precisely equal to (a multiple of) the cavity free spectral range. Since each comb line and sideband is transmitted through a separate cavity mode in exactly the same way, any residual frequency noise on the OFC relative to the cavity affects each component in an identical manner. The transmitted intensity contains a beat signal at the modulation frequency that is immune to frequency-to-amplitude noise conversion by the cavity, in a way similar to continuous wave noise-immune cavity-enhanced optical heterodyne molecular spectroscopy (NICE-OHMS). The light transmitted through the cavity is detected with a fast-scanning Fourier-transform spectrometer (FTS) and the NICE-OFCS signal is obtained by fast Fourier transform of the synchronously demodulated interferogram. Our NICE-OFCS system is based on an Er:fiber femtosecond laser locked to a cavity with a finesse of ˜9000 and a fast-scanning FTS equipped with a high-bandwidth commercial detector. We measured NICE-OFCS signals from the 3νb{1}+νb{3} overtone band of CO_2 around 1.57 μm and achieved absorption sensitivity 6.4×10-11cm-1 Hz-1/2 per spectral element, corresponding to a minimum detectable CO_2 concentration of 25 ppb after 330 s integration time. We will describe the principles of the technique and its technical implementation, and discuss the spectral lineshapes of the NICE-OFCS signals. A. Khodabakhsh, C. Abd Alrahman, and A. Foltynowicz, Opt. Lett. 39, 5034-5037 (2014). J. Ye, L. S. Ma, and J. L. Hall, J. Opt. Soc. Am. B 15, 6-15 (1998). A. Khodabakhsh, A. C. Johansson, and A. Foltynowicz, Appl. Phys. B (2015) doi:10.1007/s00340-015-6010-7.

  13. Ornamental comb colour predicts T-cell-mediated immunity in male red grouse Lagopus lagopus scoticus

    NASA Astrophysics Data System (ADS)

    Mougeot, Francois

    2008-02-01

    Sexual ornaments might reliably indicate the ability to cope with parasites and diseases, and a better ability to mount a primary inflammatory response to a novel challenge. Carotenoid-based ornaments are amongst the commonest sexual signals of birds and often influence mate choice. Because carotenoids are immuno-stimulants, signallers may trade-off allocating these to ornamental colouration or using them for immune responses, so carotenoid-based ornaments might be particularly useful as honest indicators of immuno-compentence. Tetraonid birds, such as the red grouse Lagopus lagopus scoticus, exhibit supra-orbital yellow red combs, a conspicuous ornament which functions in intra- and inter-sexual selection. The colour of combs is due to epidermal pigmentation by carotenoids, while their size is testosterone-dependent. In this study, I investigated whether comb characteristics, and in particular, comb colour, indicated immuno-competence in free-living male red grouse. I assessed T-cell-mediated immunity using a standardised challenge with phytohaemagglutinin. Red grouse combs reflect in the red and in the ultraviolet spectrum of light, which is not visible to humans but that grouse most likely see, so I measured comb colour across the whole bird visible spectrum (300 700 nm) using a reflectance spectrometer. I found that males with bigger and redder combs, but with less ultraviolet reflectance, had greater T-cell-mediated immune response. Comb colour predicted T-cell-mediated immune response better than comb size, indicating that the carotenoid-based colouration of this ornament might reliably signal this aspect of male quality.

  14. Glucose sensor based on redox-cycling between selectively modified and unmodified combs of carbon interdigitated array nanoelectrodes.

    PubMed

    Sharma, Deepti; Lim, Yeongjin; Lee, Yunjeong; Shin, Heungjoo

    2015-08-19

    We present a novel electrochemical glucose sensor employing an interdigitated array (IDA) of 1:1 aspect ratio carbon nanoelectrodes for the electrochemical-enzymatic redox cycling of redox species (ferricyanide/ferrocyanide) between glucose oxidase (GOx) and the two comb-shaped nanoelectrodes of the IDA. The carbon nanoelectrodes were fabricated using a simple, cost-effective, reproducible microfabrication technology known as the carbon-microelectromechanical-systems (C-MEMS) process. One comb (comb 1) of the IDA was selectively modified with GOx via the electrochemical reduction of an aryl diazonium salt, while the other comb (comb 2) remained unmodified; this facilitates electrochemically more active surface of comb 2, resulting in sensitive glucose detection. Ferricyanide is reduced to ferrocyanide by the GOx in the presence of glucose, and ferrocyanide diffuses to both combs of the IDA where it is oxidized. The limited electrochemical current collection at the surface-modified comb 1 is counterbalanced by the efficient redox cycling between the enzyme sites at comb 1 and the bare carbon surface of comb 2. Reducing the electrode-to-electrode gap between the two combs (gap = 1.9 μm) increases the diffusion flux of redox species at comb 2 hence, enhanced the sensitivity and limit of detection of the glucose sensor by ∼2.3 and ∼295 times, respectively at comb 2 compared to comb 1. The developed IDA-based glucose sensor demonstrated good amperometric response to glucose, affording two linear ranges from 0.001 to 1 mM and from 1 to 10 mM, with limits of detection of 0.4 and 61 μM and sensitivities of 823.2 and 70.0 μA mM(-1) cm(-2), respectively. PMID:26343443

  15. Quantum-fluctuation-initiated coherence in multioctave Raman optical frequency combs.

    PubMed

    Wang, Y Y; Wu, Chunbai; Couny, F; Raymer, M G; Benabid, F

    2010-09-17

    We show experimentally and theoretically that the spectral components of a multioctave frequency comb spontaneously created by stimulated Raman scattering in a hydrogen-filled hollow-core photonic crystal fiber exhibit strong self-coherence and mutual coherence within each 12 ns driving laser pulse. This coherence arises in spite of the field's initiation being from quantum zero-point fluctuations, which causes each spectral component to show large phase and energy fluctuations. This points to the possibility of an optical frequency comb with nonclassical correlations between all comb lines. PMID:20867639

  16. Evaluating the coherence and time-domain profile of quantum cascade laser frequency combs.

    PubMed

    Burghoff, David; Yang, Yang; Hayton, Darren J; Gao, Jian-Rong; Reno, John L; Hu, Qing

    2015-01-26

    Recently, much attention has been focused on the generation of optical frequency combs from quantum cascade lasers. We discuss how fast detectors can be used to demonstrate the mutual coherence of such combs, and present an inequality that can be used to quantitatively evaluate their performance. We discuss several technical issues related to shifted wave interference Fourier Transform spectroscopy (SWIFTS), and show how such measurements can be used to elucidate the time-domain properties of such combs, showing that they can possess signatures of both frequency-modulation and amplitude-modulation. PMID:25835878

  17. High performance tunnel injection quantum dot comb laser

    SciTech Connect

    Lee, C.-S.; Guo Wei; Basu, Debashish; Bhattacharya, Pallab

    2010-03-08

    A high-speed multiwavelength quantum dot comb laser, grown by molecular beam epitaxy, is demonstrated. The device is characterized with a 75.9 nm (full width at half maximum) and a 91.4 nm (DELTA{sub -15dB}) wide lasing spectrum. There are 105 and 185 simultaneously emitted longitudinal modes with a maximum channel intensity nonuniformity of less than 3 dB in the spectral range of 1231-1252 nm and 1274-1311 nm, respectively, for a laser with 1040 mum cavity length. The channel spacing can be tuned with cavity length and remains invariant in the temperature range of 300-323 K. The small signal modulation bandwidth is 7.5 GHz.

  18. Time-delay interferometry with optical frequency comb

    NASA Astrophysics Data System (ADS)

    Tinto, Massimo; Yu, Nan

    2015-08-01

    Heterodyne laser phase measurements in a space-based gravitational wave interferometer are degraded by the phase fluctuations of the onboard clocks, resulting in unacceptable sensitivity performance levels of the interferometric data. In order to calibrate out the clock phase noises, it has previously been suggested that additional interspacecraft phase measurements must be performed by modulating the laser beams. With the advent of self-referenced optical frequency combs, it is possible to generate a heterodyne microwave signal that is coherently referenced to the onboard laser. We show in this case that the microwave noise can be canceled directly by applying modified second-generation time-delay interferometric combinations to the heterodyne phase measurements. This approach avoids the use of modulated laser beams as well as the need for additional ultrastable oscillator clocks.

  19. Acoustic frequency combs for carrier-envelope phase stabilization.

    PubMed

    Borchers, Bastian; Lücking, Fabian; Steinmeyer, Günter

    2014-02-01

    A method for improved performance of feed-forward carrier-envelope phase stabilization in amplified laser sources is presented and experimentally demonstrated. The phase stabilization scheme is applicable for a broad range of repetition rates spanning from subhertz to 100 kHz. The method relies on driving an acousto-optic frequency shifter by few-cycle transients. The phase of these transients suitably controls the grating phase of the generated index grating inside the shifter material. This approach removes beam pointing as well as amplitude noise issues observed in continuously driven feed-forward schemes. The synthesis of these gratings can be understood as the acoustic equivalent of mode-locking or acoustic frequency combs. PMID:24487861

  20. Complex direct comb spectroscopy with a virtually imaged phased array.

    PubMed

    Scholten, Sarah K; Anstie, James D; Hébert, Nicolas Bourbeau; White, Richard T; Genest, Jérôme; Luiten, Andre N

    2016-03-15

    We demonstrate a simple interferometric technique to directly measure the complex optical transmittance over a large spectral range using a frequency-comb spectrometer based on a virtually imaged phased array. A Michelson interferometer encodes the phase deviations induced by a sample contained in one of its arms into an interferogram image. When combined with an additional image taken from each arm separately, along with a frequency-calibration image, this allows full reconstruction of the sample's optical transfer function. We demonstrate the technique with a vapor cell containing H13C14N, producing transmittance and phase spectra spanning 2.9 THz (∼23  nm) with ∼1  GHz resolution. PMID:26977688

  1. Sex during Pregnancy

    MedlinePlus

    ... Caring for Your Child All About Food Allergies Sex During Pregnancy KidsHealth > For Parents > Sex During Pregnancy ... satisfying and safe sexual relationship during pregnancy. Is Sex During Pregnancy Safe? Sex is considered safe during ...

  2. When Sex Is Painful

    MedlinePlus

    ... AQ FREQUENTLY ASKED QUESTIONS GYNECOLOGIC PROBLEMS FAQ020 When Sex Is Painful • How common is painful sex? • What causes pain during sex? • Where is pain during sex felt? • When should ...

  3. [Lethal sex].

    PubMed

    Rabinerson, David; Ben-Shitrit, Gadi; Glezerman, Marek

    2011-03-01

    Asphyxiophilic sex is a form of autoerotic activity, in which the user creates mechanical means (such as hanging or bondage) in order to achieve cerebral hypoxia, which, in turn, enhances sexual, as well as orgasmic, stimulus. Failure of safety mechanisms, created by the user, may lead to instant death as a result of asphyxiation or strangulation. This kind of sexual practice is more prevalent among men than in women. In cases of death, it is difficult to relate it to the sexual practice itself. Suicide and homicide are the main differential diagnoses. Closely related derivatives of asphyxiophilic sex are anesthesiophilia (inhalation of variable volatile substances) and electrophilia (use of electric current during sexual activity)--both also intended to enhance the sexual stimulation. These forms of sexual practice are less prevalent than asphyxiophilia. PMID:21574359

  4. Tracing part-per-billion line shifts with direct-frequency-comb Vernier spectroscopy

    NASA Astrophysics Data System (ADS)

    Siciliani de Cumis, M.; Eramo, R.; Coluccelli, N.; Cassinerio, M.; Galzerano, G.; Laporta, P.; De Natale, P.; Cancio Pastor, P.

    2015-01-01

    Accurate frequency measurements of molecular transitions around 2 μ m are performed by using a direct-frequency-comb spectroscopy approach that combines an Er+ frequency-comb oscillator at 1.5 μ m , a Tm-Ho fiber amplifier, and a Fabry-Perot-filter, high-resolution dispersive spectrometer optical multiplex-detection system. This apparatus has unique performances in terms of a wide dynamic range to integrate the intensity per comb mode, which allows one to measure molecular absorption profiles with high precision. Spectroscopic information about transition frequencies and linewidths is very accurately determined. Relative frequency uncertainties of the order of a few parts in 10-9 are achieved for rovibrational transitions of the CO2 molecule around 5100 cm-1. Moreover, tiny frequency shifts due to molecular collisions and interacting laser power using direct comb spectroscopy are investigated in a systematic way.

  5. Closed-form solutions and scaling laws for Kerr frequency combs.

    PubMed

    Renninger, William H; Rakich, Peter T

    2016-01-01

    A single closed-form analytical solution of the driven nonlinear Schrödinger equation is developed, reproducing a large class of the behaviors in Kerr-comb systems, including bright-solitons, dark-solitons, and a large class of periodic wavetrains. From this analytical framework, a Kerr-comb area theorem and a pump-detuning relation are developed, providing new insights into soliton- and wavetrain-based combs along with concrete design guidelines for both. This new area theorem reveals significant deviation from the conventional soliton area theorem, which is crucial to understanding cavity solitons in certain limits. Moreover, these closed-form solutions represent the first step towards an analytical framework for wavetrain formation, and reveal new parameter regimes for enhanced Kerr-comb performance. PMID:27108810

  6. Mode-resolved frequency comb interferometry for high-accuracy long distance measurement.

    PubMed

    van den Berg, Steven A; van Eldik, Sjoerd; Bhattacharya, Nandini

    2015-01-01

    Optical frequency combs have developed into powerful tools for distance metrology. In this paper we demonstrate absolute long distance measurement using a single femtosecond frequency comb laser as a multi-wavelength source. By applying a high-resolution spectrometer based on a virtually imaged phased array, the frequency comb modes are resolved spectrally to the level of an individual mode. Having the frequency comb stabilized against an atomic clock, thousands of accurately known wavelengths are available for interferometry. From the spectrally resolved output of a Michelson interferometer a distance is derived. The presented measurement method combines spectral interferometry, white light interferometry and multi-wavelength interferometry in a single scheme. Comparison with a fringe counting laser interferometer shows an agreement within <10(-8) for a distance of 50 m. PMID:26419282

  7. An octave-spanning mid-infrared frequency comb generated in a silicon nanophotonic wire waveguide

    PubMed Central

    Kuyken, Bart; Ideguchi, Takuro; Holzner, Simon; Yan, Ming; Hänsch, Theodor W.; Van Campenhout, Joris; Verheyen, Peter; Coen, Stéphane; Leo, Francois; Baets, Roel; Roelkens, Gunther; Picqué, Nathalie

    2015-01-01

    Laser frequency combs, sources with a spectrum consisting of hundred thousands evenly spaced narrow lines, have an exhilarating potential for new approaches to molecular spectroscopy and sensing in the mid-infrared region. The generation of such broadband coherent sources is presently under active exploration. Technical challenges have slowed down such developments. Identifying a versatile highly nonlinear medium for significantly broadening a mid-infrared comb spectrum remains challenging. Here we take a different approach to spectral broadening of mid-infrared frequency combs and investigate CMOS-compatible highly nonlinear dispersion-engineered silicon nanophotonic waveguides on a silicon-on-insulator chip. We record octave-spanning (1,500–3,300 nm) spectra with a coupled input pulse energy as low as 16 pJ. We demonstrate phase-coherent comb spectra broadened on a room-temperature-operating CMOS-compatible chip. PMID:25697764

  8. Improvement of rotated comb decimation filter magnitude characteristic using sharpening technique

    NASA Astrophysics Data System (ADS)

    Jovanovic Dolecek, Gordana

    2015-09-01

    Decreasing of sampling rate in a digital form is called decimation. This process may introduce aliasing, i.e. non desired replicas of the main spectrum of the decimated signal. That is why we need the filter before decimation. This filter is called the decimation or antialiasing filter. The most popular decimation filter is comb filter which is usually used in the first stage of decimation. However it has a high passband droop and low attenuations in the folding bands. Different methods have been proposed to improve comb magnitude characteristic. The methods based on simple zero rotations have been proposed recently. In this paper we use the sharpening technique to improve both the passband and the stopband of comb filter with the rotated zeros. The method is compared with methods based on the rotation of zeros of comb filter.

  9. Supercontinuum Comb Generation Using Optical Pulse Synthesizer and Highly Nonlinear Dispersion-Shifted Fiber

    NASA Astrophysics Data System (ADS)

    Choi, Samuel; Tamura, Naoyuki; Kashiwagi, Ken; Shioda, Tatsutoshi; Tanaka, Yosuke; Kurokawa, Takashi

    2009-09-01

    We propose a novel supercontinuum (SC) generation technology using an optical pulse synthesizer and highly nonlinear dispersion-shifted fiber. The optical pulse synthesizer enables us to reshape seed pulses optimized for broadband SC generation. 25.0 and 12.5 GHz SC combs were successfully generated by propagating synthesized seed pulses in the highly nonlinear fiber. We investigated how seed pulse conditions including shape, peak power, repetition rate, and center wavelength affect SC spectral bandwidth. We also evaluated interferometric signal waveforms from a Michelson interferometer using the generated SC comb as the light source. Interferometric peak width improved to 35.5 µm when peak power reached 7.9 W for the Gaussian pulse-based SC comb. Numerical simulation results almost agreed with experimental results. The difference between SC combs generated from Gaussian and sech2 pulses was confirmed by the simulations.

  10. Closed-form solutions and scaling laws for Kerr frequency combs

    PubMed Central

    Renninger, William H.; Rakich, Peter T.

    2016-01-01

    A single closed-form analytical solution of the driven nonlinear Schrödinger equation is developed, reproducing a large class of the behaviors in Kerr-comb systems, including bright-solitons, dark-solitons, and a large class of periodic wavetrains. From this analytical framework, a Kerr-comb area theorem and a pump-detuning relation are developed, providing new insights into soliton- and wavetrain-based combs along with concrete design guidelines for both. This new area theorem reveals significant deviation from the conventional soliton area theorem, which is crucial to understanding cavity solitons in certain limits. Moreover, these closed-form solutions represent the first step towards an analytical framework for wavetrain formation, and reveal new parameter regimes for enhanced Kerr-comb performance. PMID:27108810

  11. Mode-resolved frequency comb interferometry for high-accuracy long distance measurement

    PubMed Central

    van den Berg, Steven. A.; van Eldik, Sjoerd; Bhattacharya, Nandini

    2015-01-01

    Optical frequency combs have developed into powerful tools for distance metrology. In this paper we demonstrate absolute long distance measurement using a single femtosecond frequency comb laser as a multi-wavelength source. By applying a high-resolution spectrometer based on a virtually imaged phased array, the frequency comb modes are resolved spectrally to the level of an individual mode. Having the frequency comb stabilized against an atomic clock, thousands of accurately known wavelengths are available for interferometry. From the spectrally resolved output of a Michelson interferometer a distance is derived. The presented measurement method combines spectral interferometry, white light interferometry and multi-wavelength interferometry in a single scheme. Comparison with a fringe counting laser interferometer shows an agreement within <10−8 for a distance of 50 m. PMID:26419282

  12. Mode-resolved frequency comb interferometry for high-accuracy long distance measurement

    NASA Astrophysics Data System (ADS)

    van den Berg, Steven. A.; van Eldik, Sjoerd; Bhattacharya, Nandini

    2015-09-01

    Optical frequency combs have developed into powerful tools for distance metrology. In this paper we demonstrate absolute long distance measurement using a single femtosecond frequency comb laser as a multi-wavelength source. By applying a high-resolution spectrometer based on a virtually imaged phased array, the frequency comb modes are resolved spectrally to the level of an individual mode. Having the frequency comb stabilized against an atomic clock, thousands of accurately known wavelengths are available for interferometry. From the spectrally resolved output of a Michelson interferometer a distance is derived. The presented measurement method combines spectral interferometry, white light interferometry and multi-wavelength interferometry in a single scheme. Comparison with a fringe counting laser interferometer shows an agreement within <10-8 for a distance of 50 m.

  13. Compact, Ti:sapphire-based, methane-stabilized optical molecular frequency comb and clock.

    PubMed

    Benedick, Andrew; Tyurikov, Dmitry; Gubin, Mikhail; Shewmon, Ruth; Chuang, Issac; Kärtner, Franz X

    2009-07-15

    A compact optical clock and frequency comb system is presented, based on a 1 GHz octave-spanning Ti:sapphire laser referenced to the F2(2)(P(7),v3) optical transition in methane at 3.39 microm. The reference methane transition is accessed by a stabilized HeNe laser in a compact transportable format. The output from the octave-spanning Ti:sapphire laser is used to generate a mid-IR comb at the reference wavelength 3.39 microm. Direct comparison of the stabilized optical frequency comb with an ultralow expansion glass cavity-stabilized diode laser at 674 nm shows an Allan deviation of the frequency comb of 3x10(-14) in 20 s. PMID:19823537

  14. Offset-free broadband Yb:fiber optical frequency comb for optical clocks.

    PubMed

    Nakamura, Takuma; Ito, Isao; Kobayashi, Yohei

    2015-07-27

    We demonstrate a passively offset-frequency stabilized optical frequency comb centered at 1060 nm. The offset-free comb was achieved through difference frequency generation (DFG) between two portions of a supercontinuum based on a Yb:fiber laser. As the DFG comb had only one degree of freedom, repetition frequency, full stabilization was achieved via locking one of the modes to an ultra-stable continuous wave (CW) laser. The DFG comb provided sufficient average power to enable further amplification, using Yb-doped fiber amplifier, and spectral broadening. The spectrum spanned from 690 nm to 1300 nm and the average power was of several hundred mW, which could be ideal for the comparison of optical clocks, such as optical lattice clocks operated with Sr (698 nm) and Hg (1063 nm) reference atoms. PMID:26367597

  15. An Optical Frequency Comb Tied to GPS for Laser Frequency/Wavelength Calibration

    PubMed Central

    Stone, Jack A.; Egan, Patrick

    2010-01-01

    Optical frequency combs can be employed over a broad spectral range to calibrate laser frequency or vacuum wavelength. This article describes procedures and techniques utilized in the Precision Engineering Division of NIST (National Institute of Standards and Technology) for comb-based calibration of laser wavelength, including a discussion of ancillary measurements such as determining the mode order. The underlying purpose of these calibrations is to provide traceable standards in support of length measurement. The relative uncertainty needed to fulfill this goal is typically 10−8 and never below 10−12, very modest requirements compared to the capabilities of comb-based frequency metrology. In this accuracy range the Global Positioning System (GPS) serves as an excellent frequency reference that can provide the traceable underpinning of the measurement. This article describes techniques that can be used to completely characterize measurement errors in a GPS-based comb system and thus achieve full confidence in measurement results. PMID:27134794

  16. Optimally coherent Kerr combs generated with crystalline whispering gallery mode resonators for ultrahigh capacity fiber communications.

    PubMed

    Pfeifle, Joerg; Coillet, Aurélien; Henriet, Rémi; Saleh, Khaldoun; Schindler, Philipp; Weimann, Claudius; Freude, Wolfgang; Balakireva, Irina V; Larger, Laurent; Koos, Christian; Chembo, Yanne K

    2015-03-01

    Optical Kerr frequency combs are known to be effective coherent multiwavelength sources for ultrahigh capacity fiber communications. These combs are the frequency-domain counterparts of a wide variety of spatiotemporal dissipative structures, such as cavity solitons, chaos, or Turing patterns (rolls). In this Letter, we demonstrate that Turing patterns, which correspond to the so-called primary combs in the spectral domain, are optimally coherent in the sense that for the same pump power they provide the most robust carriers for coherent data transmission in fiber communications using advanced modulation formats. Our model is based on a stochastic Lugiato-Lefever equation which accounts for laser pump frequency jitter and amplified spontaneous emission noise induced by the erbium-doped fiber amplifier. Using crystalline whispering-gallery-mode resonators with quality factor Q∼10^{9} for the comb generation, we show that when the noise is accounted for, the coherence of a primary comb is significantly higher than the coherence of their solitonic or chaotic counterparts for the same pump power. In order to confirm this theoretical finding, we perform an optical fiber transmission experiment using advanced modulation formats, and we show that the coherence of the primary comb is high enough to enable data transmission of up to 144  Gbit/s per comb line, the highest value achieved with a Kerr comb so far. This performance evidences that compact crystalline photonic systems have the potential to play a key role in a new generation of coherent fiber communication networks, alongside fully integrated systems. PMID:25793816

  17. Holographic multichannel RF-matched filtering and fiber- optic frequency comb generation

    NASA Astrophysics Data System (ADS)

    Sefler, George Anthony

    1999-11-01

    Photorefractive holography has been used to perform correlation operations within a variety of optical pattern recognition systems. By demonstrating novel techniques for recording steady-state holograms of MHz- bandwidth time-varying waveforms, this thesis extends holographic pattern recognition to the RF domain for use in radar, target identification, and communications receivers. Angularly multiplexing reference waveform holograms within a single photorefractive crystal permits realization of a multichannel matched filter in an integrable two-dimensional geometry having performance capabilities equivalent to those of a bank of parallel analog filters. Such an optical system offers advantages in speed through parallel processing and in flexibility through the ability to program new reference waveform holograms. Two RF holographic recording techniques are developed which circumvent the relatively slow response of photorefractive crystals. The first records a static replica of the RF waveform displayed on a spatial light modulator. The second repeatedly samples the actual RF waveform being recorded with synchronized picosecond optical pulses. In this manner, RF holographic recording is effectively reduced to the recording of a static image. Optical frequency comb generators are useful for a number of applications in optical communications. A fiber-optic frequency comb generator expands a modulated lightwave into a comb of discrete, equispaced frequencies through four-wave mixing in an optical fiber. By means of a coupled-wave analysis, the sign and magnitude of the fiber dispersion are shown to control comb expansion by affecting the interference among different four-wave mixing interactions at particular comb frequencies. Positive dispersion pulls four-wave mixing interactions into phase and thus promotes comb expansion. Zero and negative dispersions suppress expansion by pulling the four-wave mixing interactions out of phase. Dispersion mapping, with decreasing positive dispersion along the fiber, engineers fiber links for maximum comb bandwidths. A frequency comb spanning 1.1 THz is experimentally demonstrated by managing dispersion in a 35 km link of dispersion-shifted fiber.

  18. Frequency-noise measurements of optical frequency combs by multiple fringe-side discriminator.

    PubMed

    Coluccelli, Nicola; Cassinerio, Marco; Gambetta, Alessio; Laporta, Paolo; Galzerano, Gianluca

    2015-01-01

    The frequency noise of an optical frequency comb is routinely measured through the hetherodyne beat of one comb tooth against a stable continuous-wave laser. After frequency-to-voltage conversion, the beatnote is sent to a spectrum analyzer to retrive the power spectral density of the frequency noise. Because narrow-linewidth continuous-wave lasers are available only at certain wavelengths, heterodyning the comb tooth can be challenging. We present a new technique for direct characterization of the frequency noise of an optical frequency comb, requiring no supplementary reference lasers and easily applicable in all spectral regions from the terahertz to the ultraviolet. The technique is based on the combination of a low finesse Fabry-Perot resonator and the so-called "fringe-side locking" method, usually adopted to characterize the spectral purity of single-frequency lasers, here generalized to optical frequency combs. The effectiveness of this technique is demonstrated with an Er-fiber comb source across the wavelength range from 1 to 2 μm. PMID:26548900

  19. Frequency-noise measurements of optical frequency combs by multiple fringe-side discriminator

    PubMed Central

    Coluccelli, Nicola; Cassinerio, Marco; Gambetta, Alessio; Laporta, Paolo; Galzerano, Gianluca

    2015-01-01

    The frequency noise of an optical frequency comb is routinely measured through the hetherodyne beat of one comb tooth against a stable continuous-wave laser. After frequency-to-voltage conversion, the beatnote is sent to a spectrum analyzer to retrive the power spectral density of the frequency noise. Because narrow-linewidth continuous-wave lasers are available only at certain wavelengths, heterodyning the comb tooth can be challenging. We present a new technique for direct characterization of the frequency noise of an optical frequency comb, requiring no supplementary reference lasers and easily applicable in all spectral regions from the terahertz to the ultraviolet. The technique is based on the combination of a low finesse Fabry-Perot resonator and the so-called “fringe-side locking” method, usually adopted to characterize the spectral purity of single-frequency lasers, here generalized to optical frequency combs. The effectiveness of this technique is demonstrated with an Er-fiber comb source across the wavelength range from 1 to 2 μm. PMID:26548900

  20. Dispersing Zwitterions into Comb Polymers for Nonviral Transfection: Experiments and Molecular Simulation.

    PubMed

    Ghobadi, Ahmadreza F; Letteri, Rachel; Parelkar, Sangram S; Zhao, Yue; Chan-Seng, Delphine; Emrick, Todd; Jayaraman, Arthi

    2016-02-01

    Polymer-based gene delivery vehicles benefit from the presence of hydrophilic groups that mitigate the inherent toxicity of polycations and that provide tunable polymer-DNA binding strength and stable complexes (polyplexes). However, hydrophilic groups screen charge, and as such can reduce cell uptake and transfection efficiency. We report the effect of embedding zwitterionic sulfobetaine (SB) groups in cationic comb polymers, using a combination of experiments and molecular simulations. Ring-opening metathesis polymerization (ROMP) produced comb polymers with tetralysine (K4) and SB pendent groups. Dynamic light scattering, zeta potential measurements, and fluorescence-based experiments, together with coarse-grained molecular dynamics simulations, described the effect of SB groups on the size, shape, surface charge, composition, and DNA binding strength of polyplexes formed using these comb polymers. Experiments and simulations showed that increasing SB composition in the comb polymers decreased polymer-DNA binding strength, while simulations indicated that the SB groups distributed throughout the polyplex. This allows polyplexes to maintain a positive surface charge and provide high levels of gene expression in live cells. Notably, comb polymers with nearly 50 mol % SB form polyplexes that exhibit positive surface charge similarly as polyplexes formed from purely cationic comb polymers, indicating the ability to introduce an appreciable amount of SB functionality without screening surface charge. This integrated simulation-experimental study demonstrates the effectiveness of incorporating zwitterions in polyplexes, while guiding the design of new and effective gene delivery vectors. PMID:26741292

  1. Modeling of a High Force Density Fishbone Shaped Electrostatic Comb Drive Microactuator

    PubMed Central

    Megat Hasnan, Megat Muhammad Ikhsan; Mohd Sabri, Mohd Faizul; Mohd Said, Suhana; Nik Ghazali, Nik Nazri

    2014-01-01

    This paper presents the design and evaluation of a high force density fishbone shaped electrostatic comb drive actuator. This comb drive actuator has a branched structure similar to a fishbone, which is intended to increase the capacitance of the electrodes and hence increase the electrostatic actuation force. Two-dimensional finite element analysis was used to simulate the motion of the fishbone shaped electrostatic comb drive actuator and compared against the performance of a straight sided electrostatic comb drive actuator. Performances of both designs are evaluated by comparison of displacement and electrostatic force. For both cases, the active area and the minimum gap distance between the two electrodes were constant. An active area of 800 × 300 μm, which contained 16 fingers of fishbone shaped actuators and 40 fingers of straight sided actuators, respectively, was used. Through simulation, improvement of drive force of the fishbone shaped electrostatic comb driver is approximately 485% higher than conventional electrostatic comb driver. These results indicate that the fishbone actuator design provides good potential for applications as high force density electrostatic microactuator in MEMS systems. PMID:25165751

  2. Thermoresponsive comb-shaped copolymer-Si(100) hybrids for accelerated temperature-dependent cell detachment.

    PubMed

    Xu, F J; Zhong, S P; Yung, L Y L; Tong, Y W; Kang, En-Tang; Neoh, K G

    2006-03-01

    Well-defined comb-shaped copolymer-Si(100) hybrids were prepared, via successive surface-initiated atom transfer radical polymerizations (ATRPs) of glycidyl methacrylate (GMA) and N-isopropylacrylamide (NIPAAm), for accelerated cell detachment at a lower temperature. The Si-C bonded comb copolymer consisted of a well-defined (nearly monodispersed) poly(glycidyl methacrylate) (P(GMA)) main chain, a well-defined NIPAAm polymer (P(NIPAAm) block, and well-defined P(NIPAAm) side chains. The ring opening reaction of epoxy groups of the P(GMA) main chain with 2-chloropropionic acid resulted in the immobilization of the alpha-chloroester groups (the ATRP initiators for the NIPAAm side chains) and the concomitant formation of hydroxyl groups. P(NIPAAm) acted as the thermoresponsive side chains of the comb copolymer for control of cell adhesion and detachment, while the P(GMA) main chain with hydroxyl groups provided a local hydrophilic microenvironment. The unique microstructure of the comb copolymer brushes facilitated cell recovery at 20 degrees C (below the lower critical solution temperature (LCST) of P(NIPAAm)) without restraining cell attachments and growth at 37 degrees C. The accelerated detachment of cells indicated that the underlying hydrophilic environment of the comb copolymer brushes contributed to speedy hydration of the P(NIPAAm) segments below the LCST. The thermoresponsive comb copolymer-Si(100) hybrids are potentially useful as adhesion modifiers for cells in silicon-based biomedical devices. PMID:16182362

  3. Frequency-noise measurements of optical frequency combs by multiple fringe-side discriminator

    NASA Astrophysics Data System (ADS)

    Coluccelli, Nicola; Cassinerio, Marco; Gambetta, Alessio; Laporta, Paolo; Galzerano, Gianluca

    2015-11-01

    The frequency noise of an optical frequency comb is routinely measured through the hetherodyne beat of one comb tooth against a stable continuous-wave laser. After frequency-to-voltage conversion, the beatnote is sent to a spectrum analyzer to retrive the power spectral density of the frequency noise. Because narrow-linewidth continuous-wave lasers are available only at certain wavelengths, heterodyning the comb tooth can be challenging. We present a new technique for direct characterization of the frequency noise of an optical frequency comb, requiring no supplementary reference lasers and easily applicable in all spectral regions from the terahertz to the ultraviolet. The technique is based on the combination of a low finesse Fabry-Perot resonator and the so-called “fringe-side locking” method, usually adopted to characterize the spectral purity of single-frequency lasers, here generalized to optical frequency combs. The effectiveness of this technique is demonstrated with an Er-fiber comb source across the wavelength range from 1 to 2 μm.

  4. Analysis of microwave frequency combs generated by semiconductor lasers under hybrid optical injections

    NASA Astrophysics Data System (ADS)

    Lin, Cheng-Ting; Wu, Yi-Hua; Juan, Yu-Shan

    2015-03-01

    Microwave frequency combs utilizing hybrid optical injections schemes by varying the operational parameters, injection strength, repetition frequency, and detuning frequency are demonstrated and characterized. The dynamical hybrid optical injections are realized by both optical pulse injection and optical cw injection to the slave laser simultaneously under the condition of zero detuning frequency between two injecting source lasers. For pure pulse injection case, the amplitude variation of ±27.3 dB in a 30 GHz range is obtained. By further applying the injection strength of the cw injection to the pulses injected semiconductor laser, the amplitude variation of ±3.3 dB in a 30 GHz range in microwave frequency combs are observed when operating the cw injection system in a stable locking state. In order to examine the microwave frequency comb precisely, each operational parameters of the hybrid optical injections schemes are analyzed. The amplitude variation of microwave frequency combs is also strongly influenced by operating the cw injection system in different states. Comparing to the cw injection system operated in period-one states, the amplitude variation is reduced when operated in the stable locking states. Moreover, the bandwidth broadening in microwave frequency comb is expected when the cw injection system operating in a stable locking state. In this paper, strongly improve the amplitude variation of the microwave frequency combs generated utilizing hybrid injections scheme compared to single injection case are obtained and compared.

  5. Lateral comb-drive MEMS structure for micro-measuring probe application

    NASA Astrophysics Data System (ADS)

    Sun, Fengming; Gao, Sai; Fu, Xing; Brand, Uwe; Herrmann, Konrad

    2011-08-01

    Electrostatic comb-drive actuators, which consists of two interdigitated finger structures with one fixed and the other connected to a compliant suspension, are the most widely used micro actuators in micro-electro-mechanical systems(MEMS). In the actuator applications, applying a voltage between the interdigitated fingers will generate a relative displacement between the fixed and the movable comb structures. The capacitance of the comb-drive structures will vary according to the variation of the relative displacement. The relationship between displacement and resulting capacitance variation is linear. With this principle, the comb-drive structure is employed as a micro measuring probe in this paper. A main shaft connected with the movable comb structures protrudes out of the MEMS chip to sense the surface topography of a specimen under test. A ruby sphere which is mounted onto the end of the actuator's main shaft is employed as a tip. The displacement of the shaft will vary with the variation of the surface topography of the specimen. Accordingly, the capacitance of the comb-drive structures will change. A capacitance readout circuit is designed to convert the capacitance variation into a voltage variation. The results of the designed electronics will be presented. And a drive and sensing system which consists of the micro measuring probe, the capacitance readout circuit, and computer controlled piezoelectric stages is constructed to measure the surface topography of the specimen. To calibrate the drive and sensing system, a standard step of 68nm is one-line scanned.

  6. Precision spectroscopy with a frequency-comb-calibrated solar spectrograph

    NASA Astrophysics Data System (ADS)

    Doerr, H.-P.

    2015-06-01

    The measurement of the velocity field of the plasma at the solar surface is a standard diagnostic tool in observational solar physics. Detailed information about the energy transport as well as on the stratification of temperature, pressure and magnetic fields in the solar atmosphere are encoded in Doppler shifts and in the precise shape of the spectral lines. The available instruments deliver data of excellent quality and precision. However, absolute wavelength calibration in solar spectroscopy was so far mostly limited to indirect methods and in general suffers from large systematic uncertainties of the order of 100 m/s. During the course of this thesis, a novel wavelength calibration system based on a laser frequency comb was deployed to the solar Vacuum Tower Telescope (VTT), Tenerife, with the goal of enabling highly accurate solar wavelength measurements at the level of 1 m/s on an absolute scale. The frequency comb was developed in a collaboration between the Kiepenheuer-Institute for Solar Physics, Freiburg, Germany and the Max Planck Institute for Quantum Optics, Garching, Germany. The efforts cumulated in the new prototype instrument LARS (Lars is an Absolute Reference Spectrograph) for solar precision spectroscopy which is in preliminary scientific operation since~2013. The instrument is based on the high-resolution echelle spectrograph of the VTT for which feed optics based on single-mode optical fibres were developed for this project. The setup routinely achieves an absolute calibration accuracy of 60 cm/s and a repeatability of 2.5 cm/s. An unprecedented repeatability of only 0.32 cm/s could be demonstrated with a differential calibration scheme. In combination with the high spectral resolving power of the spectrograph of 7x10^5 and virtually absent internal scattered light, LARS provides a spectral purity and fidelity that previously was the domain of Fourier-transform spectrometers only. The instrument therefore provides unique capabilities for precision spectroscopy of the Sun and laboratory light sources. The first scientific observations aimed at measuring the accurate wavelengths of selected solar Fraunhofer lines to characterise the so-called convective blue shift and its centre to limb variation. The convective blueshifts were derived with respect to laboratory wavelengths that were obtained from spectral lamps measured with the same instrument. The measurements agree with previous studies but provide a way higher accuracy. The data is only partially compatible with numerical simulations that were published recently. Further measurements were carried out to provide the absolute wavelengths of telluric O2 lines that are commonly used for wavelength calibration. With an accuracy of 1 m/s, these new measurements are two orders of magnitude better than existing data.

  7. Genomics of sex determination.

    PubMed

    Zhang, Jisen; Boualem, Adnane; Bendahmane, Abdelhafid; Ming, Ray

    2014-04-01

    Sex determination is a major switch in the evolutionary history of angiosperm, resulting 11% monoecious and dioecious species. The genomic sequences of papaya sex chromosomes unveiled the molecular basis of recombination suppression in the sex determination region, and candidate genes for sex determination. Identification and analyses of sex determination genes in cucurbits and maize demonstrated conservation of sex determination mechanism in one lineage and divergence between the two systems. Epigenetic control and hormonal influence of sex determination were elucidated in both plants and animals. Intensive investigation of potential sex determination genes in model species will improve our understanding of sex determination gene network. Such network will in turn accelerate the identification of sex determination genes in dioecious species with sex chromosomes, which are burdensome due to no recombination in sex determining regions. The sex determination genes in dioecious species are crucial for understanding the origin of dioecy and sex chromosomes, particularly in their early stage of evolution. PMID:24682067

  8. Mid-infrared frequency comb based on a quantum cascade laser.

    PubMed

    Hugi, Andreas; Villares, Gustavo; Blaser, Stéphane; Liu, H C; Faist, Jérôme

    2012-12-13

    Optical frequency combs act as rulers in the frequency domain and have opened new avenues in many fields such as fundamental time metrology, spectroscopy and frequency synthesis. In particular, spectroscopy by means of optical frequency combs has surpassed the precision and speed of Fourier spectrometers. Such a spectroscopy technique is especially relevant for the mid-infrared range, where the fundamental rotational-vibrational bands of most light molecules are found. Most mid-infrared comb sources are based on down-conversion of near-infrared, mode-locked, ultrafast lasers using nonlinear crystals. Their use in frequency comb spectroscopy applications has resulted in an unequalled combination of spectral coverage, resolution and sensitivity. Another means of comb generation is pumping an ultrahigh-quality factor microresonator with a continuous-wave laser. However, these combs depend on a chain of optical components, which limits their use. Therefore, to widen the spectroscopic applications of such mid-infrared combs, a more direct and compact generation scheme, using electrical injection, is preferable. Here we present a compact, broadband, semiconductor frequency comb generator that operates in the mid-infrared. We demonstrate that the modes of a continuous-wave, free-running, broadband quantum cascade laser are phase-locked. Combining mode proliferation based on four-wave mixing with gain provided by the quantum cascade laser leads to a phase relation similar to that of a frequency-modulated laser. The comb centre carrier wavelength is 7 micrometres. We identify a narrow drive current range with intermode beat linewidths narrower than 10 hertz. We find comb bandwidths of 4.4 per cent with an intermode stability of less than or equal to 200 hertz. The intermode beat can be varied over a frequency range of 65 kilohertz by radio-frequency injection. The large gain bandwidth and independent control over the carrier frequency offset and the mode spacing open the way to broadband, compact, all-solid-state mid-infrared spectrometers. PMID:23235876

  9. On the generation of octave-spanning optical frequency combs using monolithic whispering-gallery-mode microresonators.

    PubMed

    Chembo, Yanne K; Yu, Nan

    2010-08-15

    Octave-spanning optical frequency combs are especially interesting in optical metrology owing to the ability of self-referencing. We report a theoretical study on the generation of octave-spanning combs in the whispering gallery modes of a microresonator. Through a modal expansion model simulation in a calcium fluoride microcavity, we show that a combination of suitable pump power, Kerr nonlinearity, and dispersion profile can lead to stable and robust octave-spanning optical frequency combs. PMID:20717427

  10. The comb jelly opsins and the origins of animal phototransduction.

    PubMed

    Feuda, Roberto; Rota-Stabelli, Omar; Oakley, Todd H; Pisani, Davide

    2014-08-01

    Opsins mediate light detection in most animals, and understanding their evolution is key to clarify the origin of vision. Despite the public availability of a substantial collection of well-characterized opsins, early opsin evolution has yet to be fully understood, in large part because of the high level of divergence observed among opsins belonging to different subfamilies. As a result, different studies have investigated deep opsin evolution using alternative data sets and reached contradictory results. Here, we integrated the data and methods of three, key, recent studies to further clarify opsin evolution. We show that the opsin relationships are sensitive to outgroup choice; we generate new support for the existence of Rhabdomeric opsins in Cnidaria (e.g., corals and jellyfishes) and show that all comb jelly opsins belong to well-recognized opsin groups (the Go-coupled opsins or the Ciliary opsins), which are also known in Bilateria (e.g., humans, fruit flies, snails, and their allies) and Cnidaria. Our results are most parsimoniously interpreted assuming a traditional animal phylogeny where Ctenophora are not the sister group of all the other animals. PMID:25062921

  11. The Comb Jelly Opsins and the Origins of Animal Phototransduction

    PubMed Central

    Feuda, Roberto; Rota-Stabelli, Omar; Oakley, Todd H.; Pisani, Davide

    2014-01-01

    Opsins mediate light detection in most animals, and understanding their evolution is key to clarify the origin of vision. Despite the public availability of a substantial collection of well-characterized opsins, early opsin evolution has yet to be fully understood, in large part because of the high level of divergence observed among opsins belonging to different subfamilies. As a result, different studies have investigated deep opsin evolution using alternative data sets and reached contradictory results. Here, we integrated the data and methods of three, key, recent studies to further clarify opsin evolution. We show that the opsin relationships are sensitive to outgroup choice; we generate new support for the existence of Rhabdomeric opsins in Cnidaria (e.g., corals and jellyfishes) and show that all comb jelly opsins belong to well-recognized opsin groups (the Go-coupled opsins or the Ciliary opsins), which are also known in Bilateria (e.g., humans, fruit flies, snails, and their allies) and Cnidaria. Our results are most parsimoniously interpreted assuming a traditional animal phylogeny where Ctenophora are not the sister group of all the other animals. PMID:25062921

  12. Brillouin Stokes comb generated in a distributed fiber Raman amplifier

    NASA Astrophysics Data System (ADS)

    Martins, Hugo F.; Marques, Manuel B.; Frazão, Orlando

    2011-05-01

    A Brillouin Stokes comb laser with increased flatness is reported. The feedback for the laser is provided by a distributed mirror combined with a narrowband seed laser. The Brillouin seed power and wavelength optimization is crucial in order to obtain a uniform power level between Stokes lines. The Brillouin seed must have a relatively large power and its wavelength must be located close to the Raman peak gain region. The flat-amplitude bandwidth is also determined by the choice of Raman pump wavelength. A flat-amplitude bandwidth of 34 nm from 1538 nm to 1572 nm is measured when Raman pump wavelength is set to 1455 nm. 425 uniform Brillouin Stokes lines with 0.08 nm spacing are generated across the wavelength range. The average signal-to-noise ratio of 15 dB is obtained for all the Brillouin Stokes lines. This type of laser can be used in optical communications as a multiwavelength source and also in metrology as a frequency ruler.

  13. Reclassification of Acetomicrobium faecale as Caldicoprobacter faecalis comb. nov.

    PubMed

    Bouanane-Darenfed, Amel; Ben Hania, Wajdi; Cayol, Jean-Luc; Ollivier, Bernard; Fardeau, Marie-Laure

    2015-10-01

    Taking into account its phenotypical and genetic characteristics, Acetomicrobium faecale was first recognized as a member of the genus Acetomicrobium, family Bacteroidaceae, order Bacteroidales, phylum Bacteroidetes, with Acetomicrobium flavidum the type species of the genus. However, it was found that A. faecale had 95.8 %, 97.6 % and 98.4 % similarity, respectively, with Caldicoprobacter guelmensis, Caldicoprobacter algeriensis and Caldicoprobacter oshimai and only 82 % similarity with A. flavidum. The DNA G+C content of A. faecale is 45 mol , which is of the same order as the DNA G+C content of the three strains of species of the genus Caldicoprobacter and its main fatty acid is C16 : 0, with its second most prominent fatty acid, iso-C17 : 0, also common to strains of species of the genus Caldicoprobacter. On the basis of further phylogenetic, genetic and chemotaxonomic studies, we propose that A. faecale (type strain DSM 20678T = JCM 30420T) be reclassified as Caldicoprobacter faecalis comb. nov. PMID:26297233

  14. Impulse response of microresonators with a dual frequency comb probe

    NASA Astrophysics Data System (ADS)

    Michaud-Belleau, Vincent; Bergeron, Hugo; Carrier, Jean-Raphal; Roy, Julien; Genest, Jrme; Allen, Claudine

    2013-05-01

    Label-free microsphere were shown to be sensitive optical biosensors thanks to the very high quality factor up to Q ~109 of their whispering gallery modes (WGMs). Several resonances are available to probe the frequency response in polarizability, but the spectrum of WGMs for an elliptical resonator is more complicated, warranting further measures of light propagation. Our high resolution interferometric studies of a silica microresonator with a dual frequency comb provide both its impulse response in the time domain with 80 fs resolution and its transmission spectrum in the frequency domain with 125 MHz resolution, i.e. at the picometer level. We observe that a light pulse is periodically outcoupling from a ~ 156 ?m microsphere after round trips of ~ 2 ps as can be expected from the group velocity. However, the structure of the full impulse response is more rich, for example showing clusters of pulses separated by roughly ~ 50 ps. This reveals the light pulse is not outcoupling from the slightly elliptical microresonator at each round trip because its trajectory is precessing. Finally, we see that a refractive index change at the resonator surface causes a phase delay in the impulse response corresponding to the WGM frequency shifts in the spectrum.

  15. Polarized spectral combs probe optical fiber surface plasmons.

    PubMed

    Caucheteur, Christophe; Voisin, Valérie; Albert, Jacques

    2013-02-11

    The high-order cladding modes of conventional single mode fiber come in semi-degenerate pairs corresponding to mostly radially or mostly azimuthally polarized light. Using tilted fiber Bragg gratings to excite these mode families separately, we show how plasmonic coupling to a thin gold coating on the surface of the fiber modifies the effective indices of the modes differently according to polarization and to mode order. In particular, we show the existence of a single "apolarized" grating resonance, with equal effective index for all input polarization states. This special resonance provides direct evidence of the excitation of a surface plasmon on the metal surface but also an absolute wavelength reference that allows for the precise localization of the most sensitive resonances in refractometric and biochemical sensing applications. Two plasmon interrogation methods are proposed, based on wavelength and amplitude measurements. Finally, we use a biotin-streptavidin biomolecular recognition experiment to demonstrate that differential spectral transmission measurements of a fine comb of cladding mode resonances in the vicinity of the apolarized resonance provide the most accurate method to extract information from plasmon-assisted Tilted fiber Bragg gratings, down to pM concentrations and at least 10(-5) refractive index changes. PMID:23481763

  16. Dual-etalon, cavity-ring-down, frequency comb spectroscopy.

    SciTech Connect

    Strecker, Kevin E.; Chandler, David W.

    2010-10-01

    The 'dual etalon frequency comb spectrometer' is a novel low cost spectometer with limited moving parts. A broad band light source (pulsed laser, LED, lamp ...) is split into two beam paths. One travels through an etalon and a sample gas, while the second arm is just an etalon cavity, and the two beams are recombined onto a single detector. If the free spectral ranges (FSR) of the two cavities are not identical, the intensity pattern at the detector with consist of a series of heterodyne frequencies. Each mode out of the sample arm etalon with have a unique frequency in RF (radio-frequency) range, where modern electronics can easily record the signals. By monitoring these RF beat frequencies we can then determine when an optical frequencies is absorbed. The resolution is set by the FSR of the cavity, typically 10 MHz, with a bandwidth up to 100s of cm{sup -1}. In this report, the new spectrometer is described in detail and demonstration experiments on Iodine absorption are carried out. Further we discuss powerful potential next generation steps to developing this into a point sensor for monitoring combustion by-products, environmental pollutants, and warfare agents.

  17. Ultra-low noise all polarization-maintaining Er fiber-based optical frequency combs facilitated with a graphene modulator.

    PubMed

    Kuse, N; Lee, C-C; Jiang, J; Mohr, C; Schibli, T R; Fermann, M E

    2015-09-21

    High bandwidth carrier phase and repetition rate control are critical for the construction of low phase noise optical frequency combs. Here we demonstrate the use of a graphene modulator for the former and a bulk electro-optic modulator for the latter enabling record low phase noise operation of an Er fiber frequency comb. For applications that do not require carrier phase control, we show that the form factor of a fiber comb can be reduced by adapting a graphene modulator for rapid repetition rate control. Moreover, the whole system demonstration is performed with all-polarization maintaining Er fiber frequency combs, highly suitable for applications in the field. PMID:26406639

  18. Regeneration of ciliary comb plates in the ctenophore Mnemiopsis leidyi. i. morphology.

    PubMed

    Tamm, Sidney L

    2012-01-01

    Regeneration of missing body parts in model organisms provides information on the mechanisms underlying the regeneration process. The aim here is to use ctenophores to investigate regeneration of their giant ciliary swimming plates. When part of a row of comb plates on Mnemiopsis is excised, the wound closes and heals, greatly increasing the distance between comb plates near the former cut edges. Video differential interference contrast (DIC) microscopy of the regeneration of new comb plates between widely separated plates shows localized widenings of the interplate ciliated groove (ICG) first, followed by growth of two opposing groups of comb plate cilia on either side. The split parts of a new plate elongate as their bases extend laterally away from the ICG widening and continue ciliogenesis at both ends. The split parts of a new plate grow longer and move closer together into the ICG widening until they merge into a single plate that interrupts the ICG in a normal manner. Video DIC snapshots of dissected gap preparations 1.5-3-day postoperation show that ICG widenings and/or new plates do not all appear at the same time or with uniform spacing within a gap: the lengths and distances between young plates in a gap are quite variable. Video stereo microscopy of intact animals 3-4 days after the operation show that all the new plates that will form in a gap are present, fairly evenly spaced and similar in length, but smaller and closer together than normal. Normal development of comb plates in embryos and growing animals is compared to the pattern of comb plate regeneration in adults. Comb plate regeneration differs in the cydippid Pleurobrachia that lacks ICGs and has a firmer mesoglea than Mnemiopsis. This study provides a morphological foundation for histological, cellular, and molecular analysis of ciliary regeneration in ctenophores. PMID:21987455

  19. Sex-linked dominant

    MedlinePlus

    Inheritance - sex-linked dominant; Genetics - sex-linked dominant; X-linked dominant; Y-linked dominant ... type of chromosome that is affected (autosomal or sex chromosome). It also depends on whether the trait ...

  20. Highly Stable, Anion Conductive, Comb-Shaped Copolymers for Alkaline Fuel Cells

    SciTech Connect

    Li, NW; Leng, YJ; Hickner, MA; Wang, CY

    2013-07-10

    To produce an anion-conductive and durable polymer electrolyte for alkaline fuel cell applications, a series of quaternized poly(2,6-dimethyl phenylene oxide)s containing long alkyl side chains pendant to the nitrogen-centered cation were synthesized using a Menshutkin reaction to form comb-shaped structures. The pendant alkyl chains were responsible for the development of highly conductive ionic domains, as confirmed by small-angle X-ray scattering (SAXS). The comb-shaped polymers having one alkyl side chain showed higher hydroxide conductivities than those with benzyltrimethyl ammonium moieties or structures with more than one alkyl side chain per cationic site. The highest conductivity was observed for comb-shaped polymers with benzyldimethylhexadecyl ammonium cations. The chemical stabilities of the comb-shaped membranes were evaluated under severe, accelerated-aging conditions, and degradation was observed by measuring IEC and ion conductivity changes during aging. The comb-shaped membranes retained their high ion conductivity in 1 M NaOH at 80 degrees C for 2000 h. These cationic polymers were employed as ionomers in catalyst layers for alkaline fuel cells. The results indicated that the C-16 alkyl side chain ionomer had a slightly better initial performance, despite its low IEC value, but very poor durability in the fuel cell. In contrast, 90% of the initial performance was retained for the alkaline fuel cell with electrodes containing the C-6 side chain after 60 h of fuel cell operation.

  1. Modal expansion approach to optical-frequency-comb generation with monolithic whispering-gallery-mode resonators

    SciTech Connect

    Chembo, Yanne K.; Yu, Nan

    2010-09-15

    We describe a general framework based on modal expansion for the study of optical-frequency combs generated with monolithic whispering-gallery-mode resonators. We obtain a set of time-domain rate equations describing the dynamics of each mode as a function of the main characteristics of the cavity, namely, Kerr nonlinearity, absorption, coupling losses, and cavity dispersion (geometrical and material). A stability analysis of the various side modes is performed, which finds analytically the threshold power needed for comb generation. We show that the various whispering gallery modes are excited in a nontrivial way, strongly dependent on the value of the overall cavity dispersion. We demonstrate that the combs are not simply generated through a direct transfer of energy from the pumped mode to all their neighbors but rather through complex intermediate interactions. Anomalous cavity dispersion is also demonstrated to be critical for these cascading processes, and comb generation is thereby unambiguously linked to modulational instability. This theory accurately describes the emergence of spectral modulation and free spectral-range tunability in the comb. It also enables a clear understanding of the various phenomena responsible for the spectral span limitation. Our theoretical predictions are in excellent agreement with the numerical simulations, and they successfully explain the internal mechanisms responsible for the generation of hundreds of Kerr modes in monolithic whispering-gallery-mode resonators.

  2. Comb-branched Polymer Electrolytes: Architectural Changes That Promote Increased Li^+ Transport

    NASA Astrophysics Data System (ADS)

    Demille, Robert; Murthy, Sowmya; Bedrov, Dmitry; Smith, Grant

    2012-02-01

    The use of solid polymer electrolytes (SPEs) in the batteries of next generation technology applications is promising due to their safety and stability, yet is also hindered by low conductivity and high temperature requirements. Recent simulations of comb-branched poly(epoxide ether)-based SPEs have shown the comb-branched architecture to be able to overcome some of these hindrances. While providing the advantage of preventing crystallinity and allowing the optimization of the backbone to be decoupled from that of the side chain, the comb-branched SPE studied suffers from slow Li^+ cation dynamics due to coordination with the backbone. To improve Li^+ transport, we have modified the architecture of the comb-branched poly(epoxide ether) by attaching the side chains to the backbone with non-coordinating, flexible spacers. Inclusion of these spacers has resulted in a five-fold increase in the diffusion of Li^+ cation effected through 1) an increased side chain flexibility, 2) a decreased interaction of the cation with the dynamically slow backbone, and 3) quick conformational dynamics of the entire side chain. Additionally we report on other desirable architectural changes, such as including carbonate solvating moieties, to comb-branched SPEs allowing enhanced mobility of Li^+.

  3. Mechanisms behind the metabolic flexibility of an invasive comb jelly

    NASA Astrophysics Data System (ADS)

    Augustine, Starrlight; Jaspers, Cornelia; Kooijman, Sebastiaan A. L. M.; Carlotti, François; Poggiale, Jean-Christophe; Freitas, Vânia; van der Veer, Henk; van Walraven, Lodewijk

    2014-11-01

    Mnemiopsis leidyi is an invasive comb jelly which has successfully established itself in European seas. The species is known to produce spectacular blooms yet it is holoplanktonic and not much is known about its population dynamics in between. One way to gain insight on how M. leidyi might survive between blooms and how it can bloom so fast is to study how the metabolism of this species actually responds to environmental changes in food and temperature over its different life-stages. To this end we combined modelling and data analysis to study the energy budget of M. leidyi over its full life-cycle using Dynamic Energy Budget (DEB) theory and literature data. An analysis of data obtained at temperatures ranging from 8 to 30 °C suggests that the optimum thermal tolerance range of M. leidyi is higher than 12 °C. Furthermore M. leidyi seems to undergo a so-called metabolic acceleration after hatching. Intriguingly, the onset of the acceleration appears to be delayed and the data do not yet exist which allows determining what actually triggers it. It is hypothesised that this delay confers a lot of metabolic flexibility by controlling generation time. We compared the DEB model parameters for this species with those of another holoplanktonic gelatinous zooplankton species (Pelagia noctiluca). After accounting for differences in water content, the comparison shows just how fundamentally different the two energy allocation strategies are. P. noctiluca has an extremely high reserve capacity, low turnover times of reserve compounds and high resistance to shrinking. M. leidyi adopts the opposite strategy: it has a low reserve capacity, high turnover rates of reserve compounds and fast shrinking.

  4. Genomics of Sex and Sex Chromosomes

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Sex chromosomes are distinctive, not only because of their gender determining role, but also for genomic features that reflect their evolutionary history. The genomic sequences in the ancient sex chromosomes of humans and in the incipient sex chromosomes of medaka, stickleback, and papaya exhibit u...

  5. A Novel Comb Architecture for Enhancing the Sensitivity of Bulk Mode Gyroscopes

    PubMed Central

    Elsayed, Mohannad Y.; Nabki, Frederic; El-Gamal, Mourad N.

    2013-01-01

    This work introduces a novel architecture for increasing the sensitivity of bulk mode gyroscopes. It is based on adding parallel plate comb drives to the points of maximum vibration amplitude, and tuning the stiffness of the combs. This increases the drive strength and results in a significant sensitivity improvement. The architecture is targeted for technologies with ∼100 nm transducer gaps in order to achieve very high performance devices. In this work, this sensitivity enhancement concept was implemented in SOIMUMPs, a commercial relatively large gap technology. Prototypes were measured to operate at frequencies of ∼1.5 MHz, with quality factors of ∼33,000, at a 10 mTorr vacuum level. Measurements using discrete electronics show a rate sensitivity of 0.31 μV/°/s, corresponding to a capacitance sensitivity of 0.43 aF/°/s/electrode, two orders of magnitude higher than a similar design without combs, fabricated in the same technology.

  6. Doppler cooling with coherent trains of laser pulses and a tunable velocity comb

    SciTech Connect

    Ilinova, Ekaterina; Ahmad, Mahmoud; Derevianko, Andrei

    2011-09-15

    We explore the possibility of decelerating and Doppler cooling an ensemble of two-level atoms by a coherent train of short, nonoverlapping laser pulses. We derive analytical expressions for mechanical force exerted by the train. In frequency space the force pattern reflects the underlying frequency comb structure. The pattern depends strongly on the ratio of the atomic lifetime to the repetition time between the pulses and pulse area. For example, in the limit of short lifetimes, the frequency-space peaks of the optical force wash out. We propose to tune the carrier-envelope offset frequency to follow the Doppler-shifted detuning as atoms decelerate; this leads to compression of atomic velocity distribution about comb teeth and results in a ''velocity comb''--a series of narrow equidistant peaks in the velocity space.

  7. Mode-locked dark pulse Kerr combs in normal-dispersion microresonators

    NASA Astrophysics Data System (ADS)

    Xue, Xiaoxiao; Xuan, Yi; Liu, Yang; Wang, Pei-Hsun; Chen, Steven; Wang, Jian; Leaird, Dan E.; Qi, Minghao; Weiner, Andrew M.

    2015-09-01

    The generation of Kerr frequency combs in a coherently driven nonlinear microresonator is now extensively investigated more generally by the research community as a potentially portable technology for a variety of applications. Here, we report experiments in which dark pulse combs are formed in normal-dispersion microresonators with mode-interaction-assisted excitation, and mode-locking transitions are observed in the normal-dispersion regime. The mode-interaction-aided excitation of dark pulses appears to occur through a deterministic pathway, in sharp contrast to the situation for bright pulses in the anomalous dispersion region. The ability to mode-lock in the normal-dispersion regime increases the freedom in the microresonator design and may make it possible to extend Kerr comb generation into the visible, where material dispersion is likely to dominate.

  8. Molecular Combing of Single DNA Molecules on the 10 Megabase Scale.

    PubMed

    Kaykov, Atanas; Taillefumier, Thibaud; Bensimon, Aaron; Nurse, Paul

    2016-01-01

    DNA combing allows the investigation of DNA replication on genomic single DNA molecules, but the lengths that can be analysed have been restricted to molecules of 200-500 kb. We have improved the DNA combing procedure so that DNA molecules can be analysed up to the length of entire chromosomes in fission yeast and up to 12 Mb fragments in human cells. Combing multi-Mb-scale DNA molecules revealed previously undetected origin clusters in fission yeast and shows that in human cells replication origins fire stochastically forming clusters of fired origins with an average size of 370 kb. We estimate that a single human cell forms around 3200 clusters at mid S-phase and fires approximately 100,000 origins to complete genome duplication. The procedure presented here will be adaptable to other organisms and experimental conditions. PMID:26781994

  9. Molecular Combing of Single DNA Molecules on the 10 Megabase Scale

    PubMed Central

    Kaykov, Atanas; Taillefumier, Thibaud; Bensimon, Aaron; Nurse, Paul

    2016-01-01

    DNA combing allows the investigation of DNA replication on genomic single DNA molecules, but the lengths that can be analysed have been restricted to molecules of 200–500 kb. We have improved the DNA combing procedure so that DNA molecules can be analysed up to the length of entire chromosomes in fission yeast and up to 12 Mb fragments in human cells. Combing multi-Mb-scale DNA molecules revealed previously undetected origin clusters in fission yeast and shows that in human cells replication origins fire stochastically forming clusters of fired origins with an average size of 370 kb. We estimate that a single human cell forms around 3200 clusters at mid S-phase and fires approximately 100,000 origins to complete genome duplication. The procedure presented here will be adaptable to other organisms and experimental conditions. PMID:26781994

  10. Mach-zehnder based optical marker/comb generator for streak camera calibration

    SciTech Connect

    Miller, Edward Kirk

    2015-03-03

    This disclosure is directed to a method and apparatus for generating marker and comb indicia in an optical environment using a Mach-Zehnder (M-Z) modulator. High speed recording devices are configured to record image or other data defining a high speed event. To calibrate and establish time reference, the markers or combs are indicia which serve as timing pulses (markers) or a constant-frequency train of optical pulses (comb) to be imaged on a streak camera for accurate time based calibration and time reference. The system includes a camera, an optic signal generator which provides an optic signal to an M-Z modulator and biasing and modulation signal generators configured to provide input to the M-Z modulator. An optical reference signal is provided to the M-Z modulator. The M-Z modulator modulates the reference signal to a higher frequency optical signal which is output through a fiber coupled link to the streak camera.

  11. Recent developments in fiber-based optical frequency comb and its applications

    NASA Astrophysics Data System (ADS)

    Xia, Wei; Chen, Xuzong

    2016-04-01

    Fiber-based optical frequency combs, characterized by compact configuration and outstanding optical properties, have been developed into state-of-the-art precision instruments which are no longer used just for optical frequency metrology, but for a number of applications, including optical clocks, attosecond science, exoplanet searches, medical diagnostics, physicochemical processes control and advanced manufacturing. This short perspective presents some of the milestones and highlights in the evolution of fiber-based optical frequency combs and the technical revolution that are brought by them for a wide range of applications. Along the way, both the challenges and opportunities in the future development of the fiber-based optical frequency comb technology have been described as well.

  12. Fast wavelength calibration method for spectrometers based on waveguide comb optical filter

    SciTech Connect

    Yu, Zhengang; Huang, Meizhen Zou, Ye; Wang, Yang; Sun, Zhenhua; Cao, Zhuangqi

    2015-04-15

    A novel fast wavelength calibration method for spectrometers based on a standard spectrometer and a double metal-cladding waveguide comb optical filter (WCOF) is proposed and demonstrated. By using the WCOF device, a wide-spectrum beam is comb-filtered, which is very suitable for spectrometer wavelength calibration. The influence of waveguide filter’s structural parameters and the beam incident angle on the comb absorption peaks’ wavelength and its bandwidth are also discussed. The verification experiments were carried out in the wavelength range of 200–1100 nm with satisfactory results. Comparing with the traditional wavelength calibration method based on discrete sparse atomic emission or absorption lines, the new method has some advantages: sufficient calibration data, high accuracy, short calibration time, fit for produce process, stability, etc.

  13. A novel frequency control scheme for comb-referenced sensitive difference-frequency-generation spectroscopy.

    PubMed

    Iwakuni, Kana; Okubo, Sho; Sasada, Hiroyuki

    2013-06-17

    We present a novel scheme of frequency scan and wavelength modulation of a difference-frequency-generation source for comb-referenced sensitive spectroscopy. While the pump and signal frequencies are phase-locked to an optical frequency comb (OFC), the offset frequency between the signal wave and the nearest comb tooth is modulated to apply a wavelength-modulation technique, and the idler wave frequency is repeatedly swept for signal accumulation by changing the repetition frequency of the OFC. The spectrometer is applied to absolute frequency measurement of weak hyperfine-resolved rovibration transitions of the ?(1) band of CH(3)I, and the uncertainty in frequency determination is reduced by one order of magnitude in compared with that of the previous work published in Optics Express 20, 9178-9186 (2012). PMID:23787670

  14. Draft Genome Sequence of Empedobacter (Formerly Wautersiella) falsenii comb. nov. Wf282, a Strain Isolated from a Cervical Neck Abscess.

    PubMed

    Traglia, German Matías; Dixon, Chelsea; Chiem, Kevin; Almuzara, Marisa; Barberis, Claudia; Montaña, Sabrina; Merino, Cindy; Mussi, María Alejandra; Tolmasky, Marcelo E; Iriarte, Andres; Vay, Carlos; Ramírez, María Soledad

    2015-01-01

    Empedobacter (formerly Wautersiella) falsenii comb. nov. strain Wf282 was isolated from a cervical neck abscess sample from an 18-year-old female patient. The isolate was resistant to many antibiotics, including meropenem and colistin. The total DNA from the multidrug-resistant E. falsenii comb. nov. Wf282 clinical isolate was sequenced. PMID:25838490

  15. Draft Genome Sequence of Empedobacter (Formerly Wautersiella) falsenii comb. nov. Wf282, a Strain Isolated from a Cervical Neck Abscess

    PubMed Central

    Traglia, German Matías; Dixon, Chelsea; Chiem, Kevin; Almuzara, Marisa; Barberis, Claudia; Montaña, Sabrina; Merino, Cindy; Mussi, María Alejandra; Tolmasky, Marcelo E.; Iriarte, Andres; Vay, Carlos

    2015-01-01

    Empedobacter (formerly Wautersiella) falsenii comb. nov. strain Wf282 was isolated from a cervical neck abscess sample from an 18-year-old female patient. The isolate was resistant to many antibiotics, including meropenem and colistin. The total DNA from the multidrug-resistant E. falsenii comb. nov. Wf282 clinical isolate was sequenced. PMID:25838490

  16. Use of DNA combing to study DNA replication in Xenopus and human cell-free systems.

    PubMed

    Marheineke, Kathrin; Goldar, Arach; Krude, Torsten; Hyrien, Olivier

    2009-01-01

    The Xenopus egg extract has become the gold standard for in vitro studies of metazoan DNA replication. We have used this system to study the mechanisms that ensure rapid and complete DNA replication despite random initiation during Xenopus early development. To this end we adapted the DNA combing technique to investigate the distribution of replication bubbles along single DNA molecules. DNA replicating in egg extracts is labelled by addition of digoxigenin-11-dUTP and/or biotin-16-dUTP at precise times. These two dTTP analogues are efficiently incorporated into DNA during replication in the extract. After DNA purification and combing the DNA is visualized with appropriate fluorescent antibody/streptavidin molecules. Replicated DNA appears as green or red tracts whose pattern reveals how each molecule was replicated, allowing to follow the dynamics of DNA replication through S phase. We describe (a) the preparation and use of egg extracts and demembranated sperm chromatin templates; (b) a simple method for preparing silanized glass coverslips suitable for DNA combing and fluorescence detection; (c) two alternative replicative DNA labelling schemes and their respective advantages; and (d) a protocol for combining replicative labelling with detection of specific DNA sequences by fluorescent in situ hybridization (FISH). Although most observations made in Xenopus egg extracts are applicable to other eukaryotes, there are differences in cell-cycle regulation between mammalian somatic cells and embryonic amphibian cells, which led to the development of human cell-free systems that can initiate semi-conservative chromosomal DNA replication under cell-cycle control. We have employed the knowledge gained with Xenopus extracts to characterize DNA replication intermediates generated in human cell-free systems using DNA combing. We describe here (a) the preparation and use of human cell-free extracts and initiation-competent template nuclei for DNA combing studies; (b) an optimized labelling scheme for DNA replication intermediates by molecular combing and fluorescence microscopy. PMID:19563130

  17. Optical under-sampling by using a broadband optical comb with a high average power.

    PubMed

    Sherman, Alexander; Horowitz, Moshe; Zach, Shlomo

    2014-06-30

    We demonstrate a new method to improve the performance of photonic assisted analog to digital converters (ADCs) that are based on frequency down-conversion obtained by optical under-sampling. The under-sampling is performed by multiplying the radio frequency signal by ultra-low jitter broadband phase-locked optical comb. The comb wave intensity has a smooth periodic function in the time domain rather than a train of short pulses that is currently used in most photonic assisted ADCs. Hence, the signal energy at the photo-detector output can be increased and the signal to noise ratio of the system might be improved without decreasing its bandwidth. We have experimentally demonstrated a system for electro-optical under-sampling with a 6-dB bandwidth of 38.5 GHz and a spur free dynamic range of 99 dB/Hz(2/3) for a signal with a carrier frequency of 35.8 GHz, compared with 94 dB/Hz(2/3) for a signal at 6.2 GHz that was obtained in the same system when a pulsed optical source was used. The optical comb was generated by mixing signals from two dielectric resonator oscillators in a Mach-Zehnder modulator. The comb spacing is equal to 4 GHz and its bandwidth was greater than 48 GHz. The temporal jitter of the comb measured by integrating the phase noise in a frequency region of 10 kHz to 10 MHz around comb frequencies of 16 and 20 GHz was only about 15 and 11 fs, respectively. PMID:24977809

  18. Numerical investigation into the injection-locking phenomena of gain switched lasers for optical frequency comb generation

    SciTech Connect

    Ó Dúill, Sean P. Anandarajah, Prince M.; Zhou, Rui; Barry, Liam P.

    2015-05-25

    We present detailed numerical simulations of the laser dynamics that describe optical frequency comb formation by injection-locking a gain-switched laser. The typical rate equations for semiconductor lasers including stochastic carrier recombination and spontaneous emission suffice to show the injection-locking behavior of gain switched lasers, and we show how the optical frequency comb evolves starting from the free-running state, right through the final injection-locked state. Unlike the locking of continuous wave lasers, we show that the locking range for gain switched lasers is considerably greater because injection locking can be achieved by injecting at frequencies close to one of the comb lines. The quality of the comb lines is formally assessed by calculating the frequency modulation (FM)-noise spectral density and we show that under injection-locking conditions the FM-noise spectral density of the comb lines tend to that of the maser laser.

  19. Numerical investigation into the injection-locking phenomena of gain switched lasers for optical frequency comb generation

    NASA Astrophysics Data System (ADS)

    O'Dúill, Sean P.; Anandarajah, Prince M.; Zhou, Rui; Barry, Liam P.

    2015-05-01

    We present detailed numerical simulations of the laser dynamics that describe optical frequency comb formation by injection-locking a gain-switched laser. The typical rate equations for semiconductor lasers including stochastic carrier recombination and spontaneous emission suffice to show the injection-locking behavior of gain switched lasers, and we show how the optical frequency comb evolves starting from the free-running state, right through the final injection-locked state. Unlike the locking of continuous wave lasers, we show that the locking range for gain switched lasers is considerably greater because injection locking can be achieved by injecting at frequencies close to one of the comb lines. The quality of the comb lines is formally assessed by calculating the frequency modulation (FM)-noise spectral density and we show that under injection-locking conditions the FM-noise spectral density of the comb lines tend to that of the maser laser.

  20. High-resolution terahertz spectroscopy with a single tunable frequency comb.

    PubMed

    Skryl, A S; Pavelyev, D G; Tretyakov, M Y; Bakunov, M I

    2014-12-29

    We report an improvement of three orders of magnitude in the spectral resolution of a recently proposed single-comb terahertz spectroscopy [Opt. Lett.39, 5669 (2014)]. The improvement is achieved by using a femtosecond optical pulse train with a tunable repetition rate. Terahertz comb with tunable spectral line spacing generated by the train is detected via nonlinear mixing with a harmonic of a CW signal from a microwave frequency synthesizer. By applying this technique to the low-pressure gas spectroscopy, we achieved a 100 kHz spectral resolution in measuring separate absorption lines of the rotational manifold of fluoroform (CF3H). PMID:25607192

  1. Broadly tunable, low timing jitter, high repetition rate optoelectronic comb generator

    PubMed Central

    Metcalf, A. J.; Quinlan, F.; Fortier, T. M.; Diddams, S. A.; Weiner, A. M.

    2016-01-01

    We investigate the low timing jitter properties of a tunable single-pass optoelectronic frequency comb generator. The scheme is flexible in that both the repetition rate and center frequency can be continuously tuned. When operated with 10 GHz comb spacing, the integrated residual pulse-to-pulse timing jitter is 11.35 fs (1 Hz to 10 MHz) with no feedback stabilization. The corresponding phase noise at 1 Hz offset from the photodetected 10 GHz carrier is −100 dBc/Hz. PMID:26865734

  2. Comb/serpentine/cross-bridge test structure for fabrication process evaluation

    NASA Technical Reports Server (NTRS)

    Sayah, Hoshyar R.; Buehler, Martin G.

    1988-01-01

    The comb/serpentine/cross-bridge structure was developed to monitor and evaluate same layer shorts and step coverage problems (open and high-resistance wire over steps) for integrated circuit fabrication processes. The cross-bridge provides local measurements of wire sheet resistance and wirewidth. These local parametric measurements are used in the analysis of the serpentine wire, which identifies step coverage problems. The comb/serpentine/cross-bridge structure was fabricated with 3 microns CMOS/bulk p-well process and tested using a computer-controlled parametric test system.

  3. Coherent frequency combs produced by self frequency modulation in quantum cascade lasers

    SciTech Connect

    Khurgin, J. B.; Dikmelik, Y.; Hugi, A.; Faist, J.

    2014-02-24

    One salient characteristic of Quantum Cascade Laser (QCL) is its very short τ ∼ 1 ps gain recovery time that so far thwarted the attempts to achieve self-mode locking of the device into a train of single pulses. We show theoretically that four wave mixing, combined with the short gain recovery time causes QCL to operate in the self-frequency-modulated regime characterized by a constant power in time domain and stable coherent comb in the frequency domain. Coherent frequency comb may enable many potential applications of QCL's in sensing and measurement.

  4. Integrated frequency comb source based Hilbert transformer for wideband microwave photonic phase analysis.

    PubMed

    Nguyen, Thach G; Shoeiby, Mehrdad; Chu, Sai T; Little, Brent E; Morandotti, Roberto; Mitchell, Arnan; Moss, David J

    2015-08-24

    We demonstrate a photonic RF Hilbert transformer for broadband microwave in-phase and quadrature-phase generation based on an integrated frequency optical comb, generated using a nonlinear microring resonator based on a CMOS compatible, high-index contrast, doped-silica glass platform. The high quality and large frequency spacing of the comb enables filters with up to 20 taps, allowing us to demonstrate a quadrature filter with more than a 5-octave (3 dB) bandwidth and an almost uniform phase response. PMID:26368182

  5. Evidence for frequency comb emission from a Fabry-Pérot terahertz quantum-cascade laser.

    PubMed

    Wienold, M; Röben, B; Schrottke, L; Grahn, H T

    2014-12-15

    We report on a broad-band terahertz quantum-cascade laser (QCL) with a long Fabry-Pérot ridge cavity, for which the tuning range of the individual laser modes exceeds the mode spacing. While a spectral range of approximately 60 GHz (2 cm(-1)) is continuously covered by current and temperature tuning, the total emission range spans more than 270 GHz (9 cm(-1)). Within certain operating ranges, we found evidence for stable frequency comb operation of the QCL. An experimental technique is presented to characterize frequency comb operation, which is based on the self-mixing effect. PMID:25606987

  6. Brillouin-Raman comb fiber laser with cooperative Rayleigh scattering in a linear cavity.

    PubMed

    Zamzuri, A K; Md Ali, M I; Ahmad, A; Mohamad, R; Mahdi, M A

    2006-04-01

    We demonstrate a multiple-wavelength Brillouin comb laser with cooperative Rayleigh scattering that uses Raman amplification in dispersion-compensating fiber. The laser resonator is a linear cavity formed by reflector at each end of the dispersion-compensating fiber to improve the reflectivity of the Brillouin Stokes comb. Multiple Brillouin Stokes generation has been improved in terms of optical signal-to-noise ratio and power-level fluctuation between neighboring channels. Furthermore, the linewidth of the Brillouin Stokes is uniform within the laser output bandwidth. PMID:16599211

  7. Coherent combs of antimatter from nonlinear electron-positron-pair creation

    NASA Astrophysics Data System (ADS)

    Krajewska, K.; Kamiński, J. Z.

    2014-11-01

    Electron-positron-pair creation in collisions of a modulated laser pulse with a high-energy photon (nonlinear Breit-Wheeler process) is studied by means of strong-field quantum electrodynamics. It is shown that the driving pulse modulations lead to the appearance of comb structures in the energy spectra of produced positrons (electrons). It is demonstrated that these combs result from a coherent enhancement of probability amplitudes of pair creation from different modulations of the laser pulse, thus resembling the Young-type double-slit experiment for antimatter (matter) waves.

  8. Flat frequency comb generation based on efficiently multiple four-wave mixing without polarization control

    NASA Astrophysics Data System (ADS)

    Dong, Qimeng; Sun, Bao; Chen, Fushen; Jiang, Jun

    2016-03-01

    This paper presents a new technique for flat optical frequency comb (OFC) generation, which is based on the nonlinear process of multiple four-wave mixing (FWM) effects. The nonlinear effects are significantly enhanced by using the proposed optical feedback scheme consisting of a single mode fiber (SMF), two highly nonlinear fibers (HNLFs) with different zero dispersion wavelengths (ZDWs) and polarization beam splitters (PBSs). Simulation results illustrate its efficiency and applicability of expanding a comb to 128 coherent lines spaced by only 20 GHz within 6-dB power deviation.

  9. Application of Laser Frequency Combs and Nitrogen Vacancy Diamond Magnetometers to Searches for New Physics

    NASA Astrophysics Data System (ADS)

    Phillips, D. F.; Walsworth, R. L.

    2014-01-01

    Searches for new physics often benefit from improved technologies. Here we discuss possible applications of two emerging technologies to searches for physics beyond the Standard Model. First, laser frequency combs enable broad spectral coverage and coherent conversion between optical and RF signals. We are investigating tests of the nonminimal Standard-Model Extension using frequency combs coupled to broadband optical cavities. Second, nitrogen vacancy centers in diamond enable precision nanoscale magnetometry with applications from imaging to quantum science. We are investigating their use in searches for short-range spin-spin couplings.

  10. Electromagnetically induced transparency in rubidium vapor prepared by a comb of short optical pulses

    SciTech Connect

    Sautenkov, Vladimir A.; Rostovtsev, Yuri V.; Ye, C.Y.; Welch, George R.; Kocharovskaya, Olga; Scully, Marlan O.

    2005-06-15

    It was shown by Kocharovskaya and Khanin [Sov. Phys. JETP 63, 945 (1986)] that a comb of optical pulses can induce a ground-state atomic coherence and change the optical response of an atomic medium. In our experiment, we studied the propagation of a comb of optical pulses produced by a mode-locked diode laser in rubidium atomic vapor. Electromagnetically induced transparency (EIT) was observed when the pulse repetition rate is a subharmonic of the hyperfine splitting of the ground state. The width of the EIT resonance is determined by the relaxation rate of the ground-state coherence. Possible applications to magnetometery, atomic clocks, and frequency chains are discussed.

  11. The Riddle of Sex.

    ERIC Educational Resources Information Center

    Sagan, Dorion; Margulis, Lynn

    1985-01-01

    Discusses the work of evolutionary biologists in determining how sexual reproduction arose. Topics explored include the nature of sex, bacterial sex, meiotic sex, and asexual reproduction. A diagram (which can be used as a duplicating master) illustrating types of bacterial sex is included. (DH)

  12. Bacterial communities in termite fungus combs are comprised of consistent gut deposits and contributions from the environment.

    PubMed

    Otani, Saria; Hansen, Lars H; Sørensen, Søren J; Poulsen, Michael

    2016-01-01

    Fungus-growing termites (subfamily Macrotermitinae) mix plant forage with asexual spores of their plant-degrading fungal symbiont Termitomyces in their guts and deposit this blend in fungus comb structures, within which the plant matter is degraded. As Termitomyces grows, it produces nodules with asexual spores, which the termites feed on. Since all comb material passes through termite guts, it is inevitable that gut bacteria are also deposited in the comb, but it has remained unknown which bacteria are deposited and whether distinct comb bacterial communities are sustained. Using high-throughput sequencing of the 16S rRNA gene, we explored the bacterial community compositions of 33 fungus comb samples from four termite species (three genera) collected at four South African geographic locations in 2011 and 2013. We identified 33 bacterial phyla, with Firmicutes, Bacteroidetes, Proteobacteria, Actinobacteria, and Candidate division TM7 jointly accounting for 92 % of the reads. Analyses of gut microbiotas from 25 of the 33 colonies showed that dominant fungus comb taxa originate from the termite gut. While gut communities were consistent between 2011 and 2013, comb community compositions shifted over time. These shifts did not appear to be due to changes in the taxa present, but rather due to differences in the relative abundances of primarily gut-derived bacteria within fungus combs. This indicates that fungus comb microbiotas are largely termite species-specific due to major contributions from gut deposits and also that environment affects which gut bacteria dominate comb communities at a given point in time. PMID:26518432

  13. Reclassification of Bacteriovorax marinus as Halobacteriovorax marinus gen. nov., comb. nov. and Bacteriovorax litoralis as Halobacteriovorax litoralis comb. nov.; description of Halobacteriovoraceae fam. nov. in the class Deltaproteobacteria

    PubMed Central

    Williams, Henry N.; Stine, O. Colin

    2015-01-01

    The taxonomic status of saltwater Bdellovibrio-like prokaryotic predators has been revised to assign species to Halobacteriovorax gen. nov. A reclassification of Bacteriovorax marinus as Halobacteriovorax marinus comb. nov. (type strain ATCC BAA-682T = DSM 15412T) and Bacteriovorax litoralis as Halobacteriovorax litoralis comb. nov. (type strain ATCC BAA-684T = DSM 15409T) is proposed. This revision is necessary because a previous proposal to retain saltwater isolates as species of Bacteriovorax and reclassify Bacteriovorax stolpii as Bacteriolyticum stolpii was not approved. The type species of a genus cannot be reassigned to another genus. Bacteriovorax stolpii is thus retained as the type species of Bacteriovorax and Halobacteriovorax marinus is the type species of Halobacteriovorax and of Halobacteriovoraceae fam. nov. PMID:25406234

  14. Reclassification of Bacteriovorax marinus as Halobacteriovorax marinus gen. nov., comb. nov. and Bacteriovorax litoralis as Halobacteriovorax litoralis comb. nov.; description of Halobacteriovoraceae fam. nov. in the class Deltaproteobacteria.

    PubMed

    Koval, Susan F; Williams, Henry N; Stine, O Colin

    2015-02-01

    The taxonomic status of saltwater Bdellovibrio-like prokaryotic predators has been revised to assign species to Halobacteriovorax gen. nov. A reclassification of Bacteriovorax marinus as Halobacteriovorax marinus comb. nov. (type strain ATCC BAA-682(T) = DSM 15412(T)) and Bacteriovorax litoralis as Halobacteriovorax litoralis comb. nov. (type strain ATCC BAA-684(T) = DSM 15409(T)) is proposed. This revision is necessary because a previous proposal to retain saltwater isolates as species of Bacteriovorax and reclassify Bacteriovorax stolpii as Bacteriolyticum stolpii was not approved. The type species of a genus cannot be reassigned to another genus. Bacteriovorax stolpii is thus retained as the type species of Bacteriovorax and Halobacteriovorax marinus is the type species of Halobacteriovorax and of Halobacteriovoraceae fam. nov. PMID:25406234

  15. Effect of partial comb and wattle trim on pullet behavior and thermoregulation

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The wattles and comb of chickens are important for thermoregulation allowing for heat exchange during high temperatures. These integumentary tissues are sometimes trimmed to prevent tears if caught on cage equipment and to also improve feed efficiency; however, the procedure itself could be painful ...

  16. Osmotic pressure and virial coefficients of star and comb polymer solutions: Dissipative particle dynamics

    NASA Astrophysics Data System (ADS)

    Wang, Tzu-Yu; Fang, Che-Ming; Sheng, Yu-Jane; Tsao, Heng-Kwong

    2009-03-01

    The effects of macromolecular architecture on the osmotic pressure π and virial coefficients (B2 and B3) of star and comb polymers in good solvents are studied by dissipative particle dynamics simulations for both dilute and semiconcentrated regimes. The dependence of the osmotic pressure on polymer concentration is directly calculated by considering two reservoirs separated by a semipermeable, fictitious membrane. Our simulation results show that the ratios An +1≡Bn +1/R̂g3n are essentially constant and A2 and A3 are arm number (f) dependent, where R̂g is zero-density radius of gyration. The value of dimensionless virial ratio g =A3/A22 increases with arm number of stars whereas it is essentially arm number independent for comb polymers. In semiconcentrated regime the scaling relation between osmotic pressure and volume fraction, π ∝φλ, still holds for both star and comb polymers. For comb polymers, the exponent λ is close to λ∗ (≈2.73 for linear chains) and is independent of the arm number. However, for star polymers, the exponent λ deviates from λ∗ and actually grows with increasing the arm number. This may be attributed to the significant ternary interactions near the star core in the many-arm systems.

  17. Hexagonal comb cells of honeybees are not produced via a liquid equilibrium process

    NASA Astrophysics Data System (ADS)

    Bauer, Daniel; Bienefeld, Kaspar

    2013-01-01

    The nests of European honeybees ( Apis mellifera) are organised into wax combs that contain many cells with a hexagonal structure. Many previous studies on comb-building behaviour have been made in order to understand how bees produce this geometrical structure; however, it still remains a mystery. Direct construction of hexagons by bees was suggested previously, while a recent hypothesis postulated the self-organised construction of hexagonal comb cell arrays; however, infrared and thermographic video observations of comb building in the present study failed to support the self-organisation hypothesis because bees were shown to be engaged in direct construction. Bees used their antennae, mandibles and legs in a regular sequence to manipulate the wax, while some bees supported their work by actively warming the wax. During the construction of hexagonal cells, the wax temperature was between 33.6 and 37.6 °C. This is well below 40 °C, i.e. the temperature at which wax is assumed to exist in the liquid equilibrium that is essential for self-organised building.

  18. Straining graphene with low-temperature compatible electrostatic comb-drive actuators

    NASA Astrophysics Data System (ADS)

    Khodkov, Tymofiy; Goldsche, Matthias; Reichardt, Sven; Stampfer, Christoph

    2015-03-01

    Graphene holds great promises as an active element in future nano electromechanical systems. Therefore, thorough study of electromechanical properties of this 2D material is a crucial step towards its applications in flexible electronics. We present the fabrication and characterization of silicon-based electrostatic comb-drive actuators made for integrating individual graphene sheets. The micromachined comb-drive actuators are designed such that they can induce significant mechanical forces for straining graphene allowing to systematically investigate mechanical and electromechanical properties of high-quality graphene. By using highly doped silicon the comb-drive actuators become compatible with low temperatures, i.e. cryogenic temperatures allowing for quantum electromechanical experiments. Further device functionality is introduced by a local gate that enables the tunability of the chemical potential of the graphene. This approach makes possible a detailed study of the graphene under controlled high strain allowing simultaneous and independent tuning of other external parameters, i.e temperature, charge density, magnetic field. With Raman spectroscopy we measure and characterize mono and bilayer graphene samples at room temperature under applied strains up to 1%. A detailed analysis of data allows clear separation of strain and doping. It is demonstrated that with this technique graphene sheet reproducibly experiences only strain while operating the comb-drive actuator.

  19. Adaptive sampling dual terahertz comb spectroscopy using dual free-running femtosecond lasers.

    PubMed

    Yasui, Takeshi; Ichikawa, Ryuji; Hsieh, Yi-Da; Hayashi, Kenta; Cahyadi, Harsono; Hindle, Francis; Sakaguchi, Yoshiyuki; Iwata, Tetsuo; Mizutani, Yasuhiro; Yamamoto, Hirotsugu; Minoshima, Kaoru; Inaba, Hajime

    2015-01-01

    Terahertz (THz) dual comb spectroscopy (DCS) is a promising method for high-accuracy, high-resolution, broadband THz spectroscopy because the mode-resolved THz comb spectrum includes both broadband THz radiation and narrow-line CW-THz radiation characteristics. In addition, all frequency modes of a THz comb can be phase-locked to a microwave frequency standard, providing excellent traceability. However, the need for stabilization of dual femtosecond lasers has often hindered its wide use. To overcome this limitation, here we have demonstrated adaptive-sampling THz-DCS, allowing the use of free-running femtosecond lasers. To correct the fluctuation of the time and frequency scales caused by the laser timing jitter, an adaptive sampling clock is generated by dual THz-comb-referenced spectrum analysers and is used for a timing clock signal in a data acquisition board. The results not only indicated the successful implementation of THz-DCS with free-running lasers but also showed that this configuration outperforms standard THz-DCS with stabilized lasers due to the slight jitter remained in the stabilized lasers. PMID:26035687

  20. Conformational Properties of Comb-Like Polyelectrolytes: A Coarse-Grained MD Study.

    PubMed

    Ghelichi, Mahdi; Eikerling, Michael H

    2016-03-17

    This article presents a coarse-grained molecular dynamics study of single comb-like polyelectrolyte or ionomer chains in aqueous solution. The model polymer is comprised of a hydrophobic backbone chain with grafted side chains that terminate in anionic headgroups. The comb-polymer is modeled at a coarse-grained level with implicit treatment of the solvent. The computational study rationalizes conformational properties of the backbone chain and localization of counterions as functions of side chain length, grafting density of side chains, backbone stiffness, and counterion valence. The main interplay that determines the ionomer properties unfolds between electrostatic interactions among charged groups, hydrophobic backbone interactions, and steric effects induced by the pendant side chains. Depending on the density of branching sites, we have found two opposing effects of side chain length on the backbone gyration radius and local persistence length. Variation in comb-polyelectrolyte architecture is shown to have nontrivial effects on the localization of mobile counterions. Changes in Bjerrum length and counterion valence are also shown to alter the strength of Coulomb interactions and emphasize the role of excluded-volume effects on controlling the backbone conformational behavior. The results of simulations are in qualitative agreement with existing experimental and theoretical studies. The comprehensive conformational picture provides a framework for future studies of comb-polyelectrolyte systems. PMID:26910617

  1. Gravity orientation in social wasp comb cells (Vespinae) and the possible role of embedded minerals

    NASA Astrophysics Data System (ADS)

    Ishay, Jacob S.; Barkay, Zahava; Eliaz, Noam; Plotkin, Marian; Volynchik, Stanislav; Bergman, David J.

    2008-04-01

    Social wasps and hornets maintain their nest in the dark. The building of the combs by all Vespinae is always in the direction of the gravitational force of Earth, and in each cell’s ceiling, at least one ‘keystone’ is embedded and fastened by saliva. The sensory mechanisms that enable both building of sizeable symmetrical combs and nursing of the brood in the darkness merit investigation, and the aim of the present study was to identify and characterize the ‘keystones’ that exist in the ceiling and in the walls of the social wasp comb cells. Bio-ferrography was used to isolate magnetic particles on slides. These slides, as well as original cells, were analyzed in an environmental scanning electron microscope by a variety of analytical tools. It was found that both the roof and the walls of each comb cell bear minerals, like ferrites, as well as Ti and Zr. The latter two elements are less abundant in the soil around the nest. Ti and Zr are known to reflect infrared (IR) light. IR imaging showed a thermoregulatory center in the dorsal thorax of the adult Oriental hornet. It is not known yet whether these insects can sense IR light.

  2. Hexagonal comb cells of honeybees are not produced via a liquid equilibrium process.

    PubMed

    Bauer, Daniel; Bienefeld, Kaspar

    2013-01-01

    The nests of European honeybees (Apis mellifera) are organised into wax combs that contain many cells with a hexagonal structure. Many previous studies on comb-building behaviour have been made in order to understand how bees produce this geometrical structure; however, it still remains a mystery. Direct construction of hexagons by bees was suggested previously, while a recent hypothesis postulated the self-organised construction of hexagonal comb cell arrays; however, infrared and thermographic video observations of comb building in the present study failed to support the self-organisation hypothesis because bees were shown to be engaged in direct construction. Bees used their antennae, mandibles and legs in a regular sequence to manipulate the wax, while some bees supported their work by actively warming the wax. During the construction of hexagonal cells, the wax temperature was between 33.6 and 37.6 °C. This is well below 40 °C, i.e. the temperature at which wax is assumed to exist in the liquid equilibrium that is essential for self-organised building. PMID:23149932

  3. Measuring the shift of a femtosecond laser frequency comb by the interference method

    SciTech Connect

    Basnak, Dmitriy V; Bikmukhametov, K A; Dmitriev, Aleksandr K; Dychkov, Aleksandr S; Kuznetsov, Sergei A; Lugovoy, A A; Mitsziti, P

    2012-01-31

    We have demonstrated the possibility of measuring the femtosecond laser frequency comb shift by the position of a Fabry - Perot interferometer's transmission bands with a statistical error of 10{sup -2} and a systematic shift of 10{sup -1}. (control of laser radiation parameters)

  4. Power, Prayers, and Protection: Comb Ridge as a Case Study in Navajo Thought

    ERIC Educational Resources Information Center

    McPherson, Robert S.

    2010-01-01

    Beginning in 2005, a five-year survey of cultural resources began to unfold in southeastern Utah along a prominent sandstone rock formation known as Comb Ridge. This visually dramatic monocline stretches a considerable distance from the southwestern corner of Blue Mountain (Abajos) in Utah to Kayenta, Arizona, approximately one hundred miles to…

  5. Adaptive sampling dual terahertz comb spectroscopy using dual free-running femtosecond lasers

    PubMed Central

    Yasui, Takeshi; Ichikawa, Ryuji; Hsieh, Yi-Da; Hayashi, Kenta; Cahyadi, Harsono; Hindle, Francis; Sakaguchi, Yoshiyuki; Iwata, Tetsuo; Mizutani, Yasuhiro; Yamamoto, Hirotsugu; Minoshima, Kaoru; Inaba, Hajime

    2015-01-01

    Terahertz (THz) dual comb spectroscopy (DCS) is a promising method for high-accuracy, high-resolution, broadband THz spectroscopy because the mode-resolved THz comb spectrum includes both broadband THz radiation and narrow-line CW-THz radiation characteristics. In addition, all frequency modes of a THz comb can be phase-locked to a microwave frequency standard, providing excellent traceability. However, the need for stabilization of dual femtosecond lasers has often hindered its wide use. To overcome this limitation, here we have demonstrated adaptive-sampling THz-DCS, allowing the use of free-running femtosecond lasers. To correct the fluctuation of the time and frequency scales caused by the laser timing jitter, an adaptive sampling clock is generated by dual THz-comb-referenced spectrum analysers and is used for a timing clock signal in a data acquisition board. The results not only indicated the successful implementation of THz-DCS with free-running lasers but also showed that this configuration outperforms standard THz-DCS with stabilized lasers due to the slight jitter remained in the stabilized lasers. PMID:26035687

  6. Phrenology, Education, and the Politics of Human Nature: The Thought and Influence of George Combe.

    ERIC Educational Resources Information Center

    Tomlinson, Stephen

    1997-01-01

    Reviews the career and contributions of George Combe, an Edinburgh lawyer who proselytized for the cause of using phrenology in education. Although dismissed today as pseudoscience, phrenology (attributing various character traits to specific locations in the brain) was taken seriously as a science during the early 19th century. (MJP)

  7. Phase-locking to a free-space terahertz comb for metrological-grade terahertz lasers.

    PubMed

    Consolino, L; Taschin, A; Bartolini, P; Bartalini, S; Cancio, P; Tredicucci, A; Beere, H E; Ritchie, D A; Torre, R; Vitiello, M S; De Natale, P

    2012-01-01

    Optical frequency comb synthesizers have represented a revolutionary approach to frequency metrology, providing a grid of frequency references for any laser emitting within their spectral coverage. Extending the metrological features of optical frequency comb synthesizers to the terahertz domain would be a major breakthrough, due to the widespread range of accessible strategic applications and the availability of stable, high-power and widely tunable sources such as quantum cascade lasers. Here we demonstrate phase-locking of a 2.5 THz quantum cascade laser to a free-space comb, generated in a LiNbO(3) waveguide and covering the 0.1-6 THz frequency range. We show that even a small fraction (<100 nW) of the radiation emitted from the quantum cascade laser is sufficient to generate a beat note suitable for phase-locking to the comb, paving the way to novel metrological-grade terahertz applications, including high-resolution spectroscopy, manipulation of cold molecules, astronomy and telecommunications. PMID:22948822

  8. Look closer: Time sequence photography of Roosters Comb in the Sheep Creek Range, Nevada

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The importance of understanding natural landscape changes is key in properly determining rangeland ecology. Time sequence photography allows a snapshot of a landscape to be documented and enables the ability to compare natural changes overtime. Photographs of Roosters Comb were taken from the same v...

  9. A 12.5 GHz-spaced optical frequency comb spanning >400 nm for near-infrared astronomical spectrograph calibration

    SciTech Connect

    Quinlan, F.; Diddams, S. A.; Ycas, G.; Osterman, S.

    2010-06-15

    A 12.5 GHz-spaced optical frequency comb locked to a global positioning system disciplined oscillator for near-infrared (IR) spectrograph calibration is presented. The comb is generated via filtering a 250 MHz-spaced comb. Subsequent nonlinear broadening of the 12.5 GHz comb extends the wavelength range to cover 1380-1820 nm, providing complete coverage over the H-band transmission window of earth's atmosphere. Finite suppression of spurious sidemodes, optical linewidth, and instability of the comb has been examined to estimate potential wavelength biases in spectrograph calibration. Sidemode suppression varies between 20 and 45 dB, and the optical linewidth is {approx}350 kHz at 1550 nm. The comb frequency uncertainty is bounded by {+-}30 kHz (corresponding to a radial velocity of {+-}5 cm/s), limited by the global positioning system disciplined oscillator reference. These results indicate that this comb can readily support radial velocity measurements below 1 m/s in the near IR.

  10. Copy Number Variation in Intron 1 of SOX5 Causes the Pea-comb Phenotype in Chickens

    PubMed Central

    Wright, Dominic; Boije, Henrik; Meadows, Jennifer R. S.; Bed'hom, Bertrand; Gourichon, David; Vieaud, Agathe; Tixier-Boichard, Michèle; Rubin, Carl-Johan; Imsland, Freyja; Hallböök, Finn; Andersson, Leif

    2009-01-01

    Pea-comb is a dominant mutation in chickens that drastically reduces the size of the comb and wattles. It is an adaptive trait in cold climates as it reduces heat loss and makes the chicken less susceptible to frost lesions. Here we report that Pea-comb is caused by a massive amplification of a duplicated sequence located near evolutionary conserved non-coding sequences in intron 1 of the gene encoding the SOX5 transcription factor. This must be the causative mutation since all other polymorphisms associated with the Pea-comb allele were excluded by genetic analysis. SOX5 controls cell fate and differentiation and is essential for skeletal development, chondrocyte differentiation, and extracellular matrix production. Immunostaining in early embryos demonstrated that Pea-comb is associated with ectopic expression of SOX5 in mesenchymal cells located just beneath the surface ectoderm where the comb and wattles will subsequently develop. The results imply that the duplication expansion interferes with the regulation of SOX5 expression during the differentiation of cells crucial for the development of comb and wattles. The study provides novel insight into the nature of mutations that contribute to phenotypic evolution and is the first description of a spontaneous and fully viable mutation in this developmentally important gene. PMID:19521496

  11. Spatiotemporal evolution of a cosine-modulated stationary field and Kerr frequency comb generation in a microresonator.

    PubMed

    Hu, Xiaohong; Liu, Yuanshan; Xu, Xin; Feng, Ye; Zhang, Wenfu; Wang, Weiqiang; Song, Jiazheng; Wang, Yishan; Zhao, Wei

    2015-10-10

    Based on the normalized spatiotemporal Lugiato-Lefever equation, the evolutions of cosine-modulated stationary fields relating to the generation of single-free spectral range (FSR) or multi-FSR Kerr frequency combs in a microresonator with anomalous dispersion are studied numerically. The research results show that a single-FSR comb arises when a dissipative soliton pulse or multiple nonequidistant soliton pulses form in the cavity. Compared with the smooth and regular spectral structure of a single soliton pulse, the comb corresponding to the uneven distribution of multiple soliton pulses exhibits a complex and irregular profile. When the stable intracavity field consists of a "roll" Turing pattern or N(N>1) evenly distributed soliton pulses separated by 2?/N, multi-FSR combs can be generated. In the case of the "roll" Turing pattern solution, it is found that third-order dispersion could modify the comb mode spacing and decrease the intensity of high-order comb modes. For the situation of multiple soliton pulse generation, the simulation results indicate that both the number and locations of the soliton pulses can be actively controlled through the careful selection of modulation frequency. In addition, for the selected cosine-modulated initial field profile, only those modes with the mode numbers being equal to an integer multiple of N can be greatly amplified by the parametric gain during propagation in the microresonator. This process eventually leads to the formation of a N-FSR frequency comb. PMID:26479815

  12. Generation of green frequency comb from chirped χ(2) nonlinear photonic crystals

    NASA Astrophysics Data System (ADS)

    Lai, C.-M.; Chang, K.-H.; Yang, Z.-Y.; Fu, S.-H.; Tsai, S.-T.; Hsu, C.-W.; Yu, N. E.; Boudrioua, A.; Kung, A. H.; Peng, L.-H.

    2014-12-01

    Spectrally broad frequency comb generation over 510-555 nm range was reported on chirped quasi-phase-matching (QPM) χ(2) nonlinear photonic crystals of 12 mm length with periodicity stepwise increased from 5.9 μm to 7.1 μm. When pumped with nanosecond infrared (IR) frequency comb derived from a QPM optical parametric oscillator (OPO) and spanned over 1040 nm to 1090 nm wavelength range, the 520 nm to 545 nm up-converted green spectra were shown to consist of contributions from (a) second-harmonic generation among the signal or the idler modes, and (b) sum-frequency generation (SFG) from the neighboring pairs of the signal or the idler modes. These mechanisms led the up-converted green frequency comb to have the same mode spacing of 450 GHz as that in the IR-OPO pump comb. As the pump was further detuned from the aforementioned near-degeneracy point and moved toward the signal (1020-1040 nm) and the idler (1090-1110 nm) spectral range, the above QPM parametric processes were preserved in the chirped QPM devices to support up-converted green generation in the 510-520 nm and the 545-555 nm spectral regime. Additional 530-535 nm green spectral generation was also observed due to concurrence of multi-wavelength SFG processes between the (signal, idler) mode pairs. These mechanisms facilitate the chirped QPM device to support a single-pass up-conversion efficiency ˜10% when subject to an IR-OPO pump comb with 200 mW average power operated near- or off- the degeneracy point.

  13. Generation of green frequency comb from chirped χ{sup (2)} nonlinear photonic crystals

    SciTech Connect

    Lai, C.-M.; Chang, K.-H.; Yang, Z.-Y.; Fu, S.-H.; Tsai, S.-T.; Hsu, C.-W.; Peng, L.-H.; Yu, N. E.; Boudrioua, A.; Kung, A. H.

    2014-12-01

    Spectrally broad frequency comb generation over 510–555 nm range was reported on chirped quasi-phase-matching (QPM) χ{sup (2)} nonlinear photonic crystals of 12 mm length with periodicity stepwise increased from 5.9 μm to 7.1 μm. When pumped with nanosecond infrared (IR) frequency comb derived from a QPM optical parametric oscillator (OPO) and spanned over 1040 nm to 1090 nm wavelength range, the 520 nm to 545 nm up-converted green spectra were shown to consist of contributions from (a) second-harmonic generation among the signal or the idler modes, and (b) sum-frequency generation (SFG) from the neighboring pairs of the signal or the idler modes. These mechanisms led the up-converted green frequency comb to have the same mode spacing of 450 GHz as that in the IR-OPO pump comb. As the pump was further detuned from the aforementioned near-degeneracy point and moved toward the signal (1020–1040 nm) and the idler (1090–1110 nm) spectral range, the above QPM parametric processes were preserved in the chirped QPM devices to support up-converted green generation in the 510–520 nm and the 545–555 nm spectral regime. Additional 530–535 nm green spectral generation was also observed due to concurrence of multi-wavelength SFG processes between the (signal, idler) mode pairs. These mechanisms facilitate the chirped QPM device to support a single-pass up-conversion efficiency ∼10% when subject to an IR-OPO pump comb with 200 mW average power operated near- or off- the degeneracy point.

  14. Threshold conditions, energy spectrum and bands generated by locally periodic Dirac comb potentials

    NASA Astrophysics Data System (ADS)

    Dharani, M.; Shastry, C. S.

    2016-01-01

    We derive expressions for polynomials governing the threshold conditions for different types of locally periodic Dirac comb potentials comprising of attractive and combination of attractive and repulsive delta potential terms confined symmetrically inside a one dimensional box of fixed length. The roots of these polynomials specify the conditions on the potential parameters in order to generate threshold energy bound states. The mathematical and numerical methods used by us were first formulated in our earlier works and it is also very briefly summarized in this paper. We report a number of mathematical results pertaining to the threshold conditions and these are useful in controlling the number of negative energy states as desired. We further demonstrate the correlation between the distribution of roots of these polynomials and negative energy eigenvalues. Using these results as basis, we investigate the energy bands in the positive energy spectrum for the above specified Dirac comb potentials and also for the corresponding repulsive case. In the case of attractive Dirac comb the base energy of the each band excluding the first band coincides with specific eigenvalue of the confining box whereas in the repulsive case it coincides with the band top. We deduce systematic correlation between band gaps, band spreads and box eigenvalues and explain the physical reason for the vanishing of band pattern at higher energies. In the case of Dirac comb comprising of orderly arranged attractive and repulsive delta potentials, specific box eigenvalues occur in the middle of each band excluding the first band. From our study we find that by controlling the number and strength parameters of delta terms in the Dirac comb and the size of confining box it is possible to generate desired types of band formations. We believe the results from our systematic analysis are useful and relevant in the study of various one dimensional systems of physical interest in areas like nanoscience.

  15. All solid state mid-infrared dual-comb spectroscopy platform based on QCL technology

    NASA Astrophysics Data System (ADS)

    Hugi, Andreas; Geiser, Markus; Villares, Gustavo; Cappelli, Francesco; Blaser, Stephane; Faist, Jérôme

    2015-01-01

    We develop a spectroscopy platform for industrial applications based on semiconductor quantum cascade laser (QCL) frequency combs. The platform's key features will be an unmatched combination of bandwidth of 100 cm-1, resolution of 100 kHz, speed of ten to hundreds of μs as well as size and robustness, opening doors to beforehand unreachable markets. The sensor can be built extremely compact and robust since the laser source is an all-electrically pumped semiconductor optical frequency comb and no mechanical elements are required. However, the parallel acquisition of dual-comb spectrometers comes at the price of enormous data-rates. For system scalability, robustness and optical simplicity we use free-running QCL combs. Therefore no complicated optical locking mechanisms are required. To reach high signal-to-noise ratios, we develop an algorithm, which is based on combination of coherent and non-coherent averaging. This algorithm is specifically optimized for free-running and small footprint, therefore high-repetition rate, comb sources. As a consequence, our system generates data-rates of up to 3.2 GB/sec. These data-rates need to be reduced by several orders of magnitude in real-time in order to be useful for spectral fitting algorithms. We present the development of a data-treatment solution, which reaches a single-channel throughput of 22% using a standard laptop-computer. Using a state-of-the art desktop computer, the throughput is increased to 43%. This is combined with a data-acquisition board to a stand-alone data processing unit, allowing real-time industrial process observation and continuous averaging to achieve highest signal fidelity.

  16. Wide-bandwidth phase lock between a CW laser and a frequency comb based on a feed-forward configuration.

    PubMed

    Sala, T; Gatti, D; Gambetta, A; Coluccelli, N; Galzerano, G; Laporta, P; Marangoni, M

    2012-07-01

    Wide-bandwidth phase lock between the tooth of a frequency comb and a CW extended-cavity diode laser at 1.55 μm is achieved by the use of an acousto-optical frequency shifter in a feed-forward configuration. The coherence properties of the comb are efficiently transferred to the CW laser, whose linewidth is narrowed down to the ∼10 KHz comb level. A maximum control bandwidth of ∼0.6 MHz has been experimentally achieved, limited by the transit time of the acoustic wave inside the frequency shifter. PMID:22743465

  17. Simultaneous low noise radio frequency tone and narrow linewidth optical comb generation from a regeneratively mode-locked laser

    NASA Astrophysics Data System (ADS)

    Ozdur, Ibrahim; Ozharar, Sarper; Delfyett, Peter J.

    2014-10-01

    A regeneratively mode-locked laser with simultaneous low noise radio frequency (RF) tone and optical comb generation is presented. The laser does not need any external RF signal and emits a pulse train at 10 GHz repetition rate with a 1.5-ps optical pulse width after compression. The generated RF tone has a signal-to-noise ratio of 121 dB/Hz and an RF fluctuation of 10-9 over 0.1 s. The optical frequency comb spacing is also at 10 GHz and the optical comb tooth has a linewidth of <1 kHz.

  18. Generation of Kerr combs centered at 45 μm in crystalline microresonators pumped with quantum-cascade lasers

    NASA Astrophysics Data System (ADS)

    Savchenkov, Anatoliy A.; Ilchenko, Vladimir S.; Di Teodoro, Fabio; Belden, Paul M.; Lotshaw, William T.; Matsko, Andrey B.; Maleki, Lute

    2015-08-01

    We report on the generation of mid-infrared Kerr frequency combs in high-finesse CaF$_2$ and MgF$_2$ whispering-gallery mode resonators pumped with continuous wave room temperature quantum cascade lasers. The combs were centered at 4.5$\\mu$m, the longest wavelength to date. A frequency comb wider than a half of an octave was demonstrated when approximately 20mW of pump power was coupled to an MgF2 resonator characterized with quality factor exceeding 10$^8$.

  19. Plant Sex Chromosomes.

    PubMed

    Charlesworth, Deborah

    2016-04-29

    Although individuals in most flowering plant species, and in many haploid plants, have both sex functions, dioecious species-in which individuals have either male or female functions only-are scattered across many taxonomic groups, and many species have genetic sex determination. Among these, some have visibly heteromorphic sex chromosomes, and molecular genetic studies are starting to uncover sex-linked markers in others, showing that they too have fully sex-linked regions that are either too small or are located in chromosomes that are too small to be cytologically detectable from lack of pairing, lack of visible crossovers, or accumulation of heterochromatin. Detailed study is revealing that, like animal sex chromosomes, plant sex-linked regions show evidence for accumulation of repetitive sequences and genetic degeneration. Estimating when recombination stopped confirms the view that many plants have young sex-linked regions, making plants of great interest for studying the timescale of these changes. PMID:26653795

  20. Sex Education: Another View

    ERIC Educational Resources Information Center

    Hamilton, Jennifer

    1977-01-01

    The mother of a 14-year-old mentally retarded boy comments on the viewpoints of Dr. Sol Gordon (a sex education columnist) regarding masturbation, questions on sex, marriage, and the parents' role. (SBH)

  1. Practice Safer Sex

    MedlinePlus

    ... This information in Spanish ( en español ) Practice safer sex Related information Men's health Screening tests and vaccines ... Return to top More information on Practice safer sex Explore other publications and websites Addressing HIV, Other ...

  2. Same sex, no sex, and unaware sex in neurotoxicology.

    PubMed

    Weiss, Bernard

    2011-10-01

    Males and females of virtually all species differ in how they respond to their environment. Because such differences exist in almost all biological realms, including disease patterns and therapeutic outcomes, they have evoked calls by various bodies to incorporate their assessment in research. Neurobehavioral indices pose special questions because, unlike outwardly visible markers, they are described by complex functional outcomes or subtle alterations in brain structure. These divergent responses arise because they are inscribed in the genome itself and then by endocrine mechanisms that govern sexual differentiation of the brain during development and operate throughout life. Other organ systems that exhibit sex differences include the liver, an important consideration for neurotoxicology because it may process many toxic chemicals differentially in males and females. Despite the scope and pervasiveness of sex differences, however, they are disregarded by much of neurotoxicology research. Males predominate in behavioral experiments, few such experiments study both sexes, some investigators fail to even describe the sex of their subjects, and in vitro studies tend to wholly ignore sex, even for model systems aimed at neurological disorders that display marked sex differences. The public is acutely aware of sex differences in behavior, as attested by its appetite for books on the topic. It closely follows debates about the proportion of women in professions that feature science and mathematics. Neurotoxicology, especially in the domain of laboratory research, will be hindered in its ability to translate its findings into human health measures if it assigns sex differences to a minor role. It must also be sensitive to how such debates are framed. Often, the differences evoking the most discussion are subtle in scope. They do not lend themselves to the typical analyses conducted by experimenters; that is, reliance on mean differences and null hypothesis testing. PMID:20875453

  3. Family Sex Communication Orientation.

    ERIC Educational Resources Information Center

    Warren, Clay; Neer, Michael

    1986-01-01

    Suggests (1) family sex communication is infrequent and ineffective, (2) frequent, effective family sex communication may serve as a contextual model for children's communication patterns, (3) strong family sex communication orientation seems to facilitate children's open discussion with dates and parents, and develops responsible pre-parenting…

  4. Sex Differences in Cognition

    ERIC Educational Resources Information Center

    Fairweather, Hugh

    1976-01-01

    Sex differences in cognitive skills, grouped into motor, spatial and linguistic areas, are assessed in relation to current theories of cerebral lateralization. Few convincing sex differences exist, either overall, or in interactions with functional localization. Qualifying criteria include age, birth order, culture, sex of experimenter and sex…

  5. Integrated Sex Education

    PubMed Central

    Vandermaas, Alan

    1974-01-01

    If sex education consists of factual information only, a distorted picture results. Children and teenagers can teach us how sex is firmly embedded in the whole person, which should direct us in our approach. The problems of parental embarrassment, of finding opportunities and of the sex education we give unwittingly, are touched on. PMID:20469123

  6. Changing Sex Roles.

    ERIC Educational Resources Information Center

    Worell, Judith

    This article reviews literature on sex role change in children and points to areas which need further research. Competing ideologies which support or reject sex typing of role behaviors are briefly discussed in the introduction. The sources of sex role change are divided into two categories: (1) planned direct intervention programs and (2) natural…

  7. Generation of Optical Combs in a WGM Resonator from a Bichromatic Pump

    NASA Technical Reports Server (NTRS)

    Strekalov, Dmitry V.; Yu, Nan; Matsko, Andrey B.

    2010-01-01

    Optical combs generated by a monolithic resonator with Kerrmedium can be used in a number of applications, including orbital clocks and frequency standards of extremely high accuracy, such as astronomy, molecular spectroscopy, and the like. The main difficulty of this approach is the relatively high pump power that has to be used in such devices, causing undesired thermorefractive effects, as well as stimulated Raman scattering, and limiting the optical comb quality and utility. In order to overcome this problem, this innovation uses a different approach to excitation of the nonlinear oscillations in a Kerr-nonlinear whispering gallery mode (WGM) resonator and generation of the optical comb. By coupling to the resonator two optical pump frequencies instead of just one, the efficiency of the comb source can be increased considerably. It therefore can operate in a lowerpower regime where the undesirable effects are not present. This process does not have a power threshold; therefore, the new optical component can easily be made strong enough to generate further components, making the optical comb spread in a cascade fashion. Additionally, the comb spacing can be made in an arbitrary number of the resonator free spectral ranges (FSR). The experimental setup for this innovation used a fluorite resonator with OMEGA= 13.56 GHz. This material has very low dispersion at the wavelength of 1.5 microns, so the resonator spectrum around this wavelength is highly equidistant. Light was coupled in and out of the resonator using two optical fibers polished at the optimal coupling angle. The gap between the resonator and the fibers, affecting the light coupling and the resonator loading, was controlled by piezo positioners. The light from the input fiber that did not go into the resonator reflected off of its rim, and was collected by a photodetector. This enabled observation and measurement of the (absorption) spectrum of the resonator. The input fiber combined light from two lasers centered at around 1,560 nanometers. Both laser frequencies were simultaneously scanned around the selected WGMs of the same family. However, they were separated by one, two, three, or ten FSRs. This was achieved by fine-tuning each laser frequency offset until the selected resonances overlap on the oscilloscope screen. The resonator quality factor Q = 7 x 10(exp 7) was relatively low to increase the linewidth and, therefore, the duty cycle of both lasers simultaneously coupled into their WGMs. The optical spectrum analyzer (OSA) connected to the output fiber was continuously acquiring data, asynchronously with the laser scan. The instrument was set to retain the peak power values; therefore, a trace recorded for a sufficiently long period of time reflected the situation with both lasers maximally coupled to the WGMs.

  8. Wavelength and bandwidth-tunable silicon comb filter based on Sagnac loop mirrors with Mach-Zehnder interferometer couplers.

    PubMed

    Jiang, Xinhong; Wu, Jiayang; Yang, Yuxing; Pan, Ting; Mao, Junming; Liu, Boyu; Liu, Ruili; Zhang, Yong; Qiu, Ciyuan; Tremblay, Christine; Su, Yikai

    2016-02-01

    We propose and experimentally demonstrate a wavelength and bandwidth-tunable comb filter based on silicon Sagnac loop mirrors (SLMs) with Mach-Zehnder interferometer (MZI) couplers. By thermally tuning the MZI couplers in common and differential modes, the phase shift and reflectivity of the SLMs can be changed, respectively, leading to tunable wavelength and bandwidth of the comb filter. The fabricated comb filter has 93 comb lines in the wavelength range from 1535 nm to 1565 nm spaced by ~0.322 nm. The central wavelength can be red-shifted by ~0.462 nm with a tuning efficiency of ~0.019 nm/mW. A continuously tunable bandwidth from 5.88 GHz to 24.89 GHz is also achieved with a differential heating power ranging from 0.00 mW to 0.53 mW. PMID:26906794

  9. Measurement of the carrier envelope offset frequency of a femtosecond frequency comb using a Fabry—Perot interferometer

    NASA Astrophysics Data System (ADS)

    Basnak, D. V.; Bikmukhametov, K. A.; Dmitriev, Aleksandr K.; Dmitrieva, N. I.; Lugovoi, A. A.; Pokasov, P. V.; Chepurov, S. V.

    2010-10-01

    A method for measuring the carrier envelope offset (CEO) frequency of the femtosecond frequency comb with a bandwidth of less than one octave by using a Fabry—Perot interferometer is proposed and experimentally demonstrated.

  10. Spectral self-imaging of time-periodic coherent frequency combs by parabolic cross-phase modulation.

    PubMed

    Maram, Reza; Azaña, José

    2013-11-18

    Integer and fractional spectral self-imaging effects are induced on infinite-duration periodic frequency combs (probe signal) using cross-phase modulation (XPM) with a parabolic pulse train as pump signal. Free-spectral-range tuning (fractional effects) or wavelength-shifting (integer effects) of the frequency comb can be achieved by changing the parabolic pulse peak power or/and repetition rate without affecting the spectral envelope shape and bandwidth of the original comb. For design purposes, we derive the complete family of different pump signals that allow implementing a desired spectral self-imaging process. Numerical simulation results validate our theoretical analysis. We also investigate the detrimental influence of group-delay walk-off and deviations in the nominal temporal shape or power of the pump pulses on the generated output frequency combs. PMID:24514395

  11. Measurement of the carrier envelope offset frequency of a femtosecond frequency comb using a Fabry-Perot interferometer

    SciTech Connect

    Basnak, D V; Bikmukhametov, K A; Dmitrieva, N I; Dmitriev, Aleksandr K; Lugovoi, A A; Pokasov, P V; Chepurov, S V

    2010-10-15

    A method for measuring the carrier envelope offset (CEO) frequency of the femtosecond frequency comb with a bandwidth of less than one octave by using a Fabry-Perot interferometer is proposed and experimentally demonstrated. (laser components)

  12. Sandstone petrology and diagenesis of lower Tuscaloosa Formation reservoirs in McComb and Little Creek field areas, southwest Mississippi

    SciTech Connect

    Hamlin, K.H.; Cameron, C.P.

    1987-09-01

    Two major depositional facies characterize producing lower Tuscaloosa Formation (Upper Cretaceous) sandstone reservoirs in the McComb-Little Creek field areas: a lower fluvial sequence (Denkman sand) topped by nearshore marine deposits (McComb sand). Petrographic studies reveal that the sandstones of both fields were deposited as very fine to medium-grained quartzarenites and quartz litharenites. Petrographic and x-ray diffraction analyses of the clay mineral content of the sandstones indicate that most of the clays are authigenic and comprise a suite which includes chlorite, kaolinite, mixed-layer illite/smectite, and illite. Mixed-layer illite/smectite appears to be considerably more abundant in the McComb reservoir sandstones than at Little Creek. The reservoir sandstones in the McComb and Little Creek fields are highlighted by good secondary porosity (3-27%, average 19%) developed through dissolution of rock fragments and carbonate cements.

  13. Patterns of comb row development in young and adult stages of the ctenophores Mnemiopsis leidyi and Pleurobrachia pileus.

    PubMed

    Tamm, Sidney L

    2012-09-01

    The development of comb rows in larval and adult Mnemiopsis leidyi and adult Pleurobrachia pileus is compared to regeneration of comb plates in these ctenophores. Late gastrula embryos and recently hatched cydippid larvae of Mnemiopsis have five comb plates in subsagittal rows and six comb plates in subtentacular rows. Subsagittal rows develop a new (sixth) comb plate and both types of rows add plates at similar rates until larvae reach the transition to the lobate form at ∼5 mm size. New plate formation then accelerates in subsagittal rows that later extend on the growing oral lobes to become twice the length of subtentacular rows. Interplate ciliated grooves (ICGs) develop in an aboral-oral direction along comb rows, but ICG formation itself proceeds from oral to aboral between plates. New comb plates in Mnemiopsis larvae are added at both aboral and oral ends of rows. At aboral ends, new plates arise as during regeneration: local widening of a ciliated groove followed by formation of a short split plate that grows longer and wider and joins into a common plate. At oral ends, new plates arise as a single tuft of cilia before an ICG appears. Adult Mnemiopsis continue to make new plates at both ends of rows. The frequency of new aboral plate formation varies in the eight rows of an animal and seems unrelated to body size. In Pleurobrachia that lack ICGs, new comb plates at aboral ends arise between the first and second plates as a single small nonsplit plate, located either on the row midline or off-axis toward the subtentacular plane. As the new (now second) plate grows larger, its distance from the first and third plates increases. Size of the new second plate varies within the eight rows of the same animal, indicating asynchronous formation of plates as in Mnemiopsis. New oral plates arise as in Mnemiopsis. The different modes of comb plate formation in Mnemiopsis versus Pleurobrachia are accounted for by differences in mesogleal firmness and mechanisms of ciliary coordination. In both cases, the body of a growing ctenophore is supplied with additional comb plates centripetally from opposite ends of the comb rows. PMID:22729952

  14. Generation of Flat Optical Frequency Comb based on Mach-Zehnder Modulator and Recirculating Frequency Shifter Loop

    NASA Astrophysics Data System (ADS)

    Wu, Shibao; Li, Yulong; Fei, Yue; Hu, Faze

    2014-06-01

    We propose a novel scheme to generate optical frequency comb by using Mach-Zehnder modulator and recirculating frequency shifter loop based on IQ modulator driven by radio frequency clock signals. A system of 4 flat and stable comb lines generation based on Mach-Zehnder modulator is set as the seed light source of the recirculating loop. Through theorical analysis and simulation it is shown that the proposed theoretical model is proved in good agreement with simulation results.

  15. Novel comb polymers from alternating N-acylated poly(aminoester)s obtained by spontaneous zwitterionic copolymerisation.

    PubMed

    Kempe, Kristian; de Jongh, Patrick A J M; Anastasaki, Athina; Wilson, Paul; Haddleton, David M

    2015-11-21

    N-Acylated poly(aminoester) (NPAE) macromonomers were synthesised via spontaneous copolymerisation of 2-oxazolines and acrylic acid. Inherent quantitative introduction of α-vinyl end-groups was observed, which enabled the preparation of a series of well-defined NPAE comb polymers through redox-initiated RAFT polymerisation. Investigations of the thermal properties of the comb polymers revealed similarities to poly(2-oxazoline) based systems. PMID:26400482

  16. Measurement of carrier envelope offset frequency for a 10 GHz etalon-stabilized semiconductor optical frequency comb

    NASA Astrophysics Data System (ADS)

    Akbulut, M.; Davila-Rodriguez, J.; Ozdur, I.; Quinlan, F.; Ozharar, S.; Hoghooghi, N.; Delfyett, P. J.

    2011-08-01

    We report Carrier Envelope Offset (CEO) frequency measurements of a 10 GHz harmonically mode-locked, Fabry-Perot etalon-stabilized, semiconductor optical frequency comb source. A modified multi-heterodyne mixing technique with a reference frequency comb was utilized for the measurement. Also, preliminary results from an attempt at f-2f self-referencing measurement are presented. The CEO frequency was found to be ~1.47 GHz for the particular etalon that was used.

  17. Sexing young snowy owls

    USGS Publications Warehouse

    Seidensticker, M.T.; Holt, D.W.; Detienne, J.; Talbot, S.; Gray, K.

    2011-01-01

    We predicted sex of 140 Snowy Owl (Bubo scandiacus) nestlings out of 34 nests at our Barrow, Alaska, study area to develop a technique for sexing these owls in the field. We primarily sexed young, flightless owls (3844 d old) by quantifying plumage markings on the remiges and tail, predicting sex, and collecting blood samples to test our field predictions using molecular sexing techniques. We categorized and quantified three different plumage markings: two types of bars (defined as markings that touch the rachis) and spots (defined as markings that do not touch the rachis). We predicted sex in the field assuming that males had more spots than bars and females more bars than spots on the remiges and rectrices. Molecular data indicated that we correctly sexed 100% of the nestlings. We modeled the data using random forests and classification trees. Both models indicated that the number and type of markings on the secondary feathers were the most important in classifying nestling sex. The statistical models verified our initial qualitative prediction that males have more spots than bars and females more bars than spots on flight feathers P6P10 for both wings and tail feathers T1 and T2. This study provides researchers with an easily replicable and highly accurate method for sexing young Snowy Owls in the field, which should aid further studies of sex-ratios and sex-related variation in behavior and growth of this circumpolar owl species. ?? 2011 The Raptor Research Foundation, Inc.

  18. Osho - Insights on sex

    PubMed Central

    Nagaraj, Anil Kumar Mysore

    2013-01-01

    Sex is a mysterious phenomenon, which has puzzled even great sages. Human beings have researched and mastered the biology of sex. But that is not all. Sex needs to be understood from the spiritual perspective too. The vision of Osho is an enlightening experience in this regard. Out of the thousands of lectures, five lectures on sex made Osho most notorious. Born into a Jain family of Madhya Pradesh, Rajneesh, who later wanted himself to be called Osho, is a great master. He has spoken volumes on a wide range of topics ranging from sex to super-consciousness. His contributions in the area of sex are based on the principles of “Tantra” which has its origin from Buddhism. This article focuses on his life and insights on sex, which if understood properly, can be a stepping stone for enlightenment. PMID:23858266

  19. Osho - Insights on sex.

    PubMed

    Nagaraj, Anil Kumar Mysore

    2013-01-01

    Sex is a mysterious phenomenon, which has puzzled even great sages. Human beings have researched and mastered the biology of sex. But that is not all. Sex needs to be understood from the spiritual perspective too. The vision of Osho is an enlightening experience in this regard. Out of the thousands of lectures, five lectures on sex made Osho most notorious. Born into a Jain family of Madhya Pradesh, Rajneesh, who later wanted himself to be called Osho, is a great master. He has spoken volumes on a wide range of topics ranging from sex to super-consciousness. His contributions in the area of sex are based on the principles of "Tantra" which has its origin from Buddhism. This article focuses on his life and insights on sex, which if understood properly, can be a stepping stone for enlightenment. PMID:23858266

  20. Coherent control of multiphoton resonance dynamics in high-order-harmonic generation driven by two frequency-comb fields

    NASA Astrophysics Data System (ADS)

    Zhao, Di; Jiang, Chen-Wei; Li, Fu-li

    2015-10-01

    We present a theoretical investigation of the multiphoton resonance dynamics in the high-order-harmonic generation (HHG) process driven by two frequency-comb fields with the carrier frequencies of fundamental and second harmonics, respectively. The many-mode Floquet theorem is employed to provide a nonperturbative and exact treatment of the interaction between a quantum system and frequency-comb laser fields. The coupling of the weak second-harmonic control frequency-comb laser field promises more routes to coherently optimize the multiphoton resonance dynamics and HHG power spectra. First, even-order harmonics are generated due to the coupling of the second-harmonic frequency-comb field. Second, the HHG power spectra can be greatly enhanced via multiphoton resonance, which can be achieved by tuning the carrier-envelope-phase (CEP) shifts and the peak intensities of both frequency-comb fields. Furthermore, besides the multiphoton transitions involving only fundamental-harmonic photons, additional multiphoton transitions involving both fundamental- and second-harmonic photons occur, resulting in the generation of combs with frequencies dependent on CEP shifts of both fields. Different multiphoton transition paths can interfere with each other when the two CEP shifts are matching, and the interference of paths allows one to coherently control the HHG power spectra by varying the relative phase between the fields.

  1. Generation of optical frequency combs via four-wave mixing processes for low- and medium-resolution astronomy

    NASA Astrophysics Data System (ADS)

    Zajnulina, M.; Boggio, J. M. Chavez; Böhm, M.; Rieznik, A. A.; Fremberg, T.; Haynes, R.; Roth, M. M.

    2015-07-01

    We investigate the generation of optical frequency combs through a cascade of four-wave mixing processes in nonlinear fibres with optimised parameters. The initial optical field consists of two continuous-wave lasers with frequency separation larger than 40 GHz (312.7 pm at 1531 nm). It propagates through three nonlinear fibres. The first fibre serves to pulse shape the initial sinusoidal-square pulse, while a strong pulse compression down to sub-100 fs takes place in the second fibre which is an amplifying erbium-doped fibre. The last stage is a low-dispersion highly nonlinear fibre where the frequency comb bandwidth is increased and the line intensity is equalised. We model this system using the generalised nonlinear Schrödinger equation and investigate it in terms of fibre lengths, fibre dispersion, laser frequency separation and input powers with the aim to minimise the frequency comb noise. With the support of the numerical results, a frequency comb is experimentally generated, first in the near infra-red and then it is frequency-doubled into the visible spectral range. Using a MUSE-type spectrograph, we evaluate the comb performance for astronomical wavelength calibration in terms of equidistancy of the comb lines and their stability.

  2. Unified approach to cascaded stimulated Brillouin scattering and frequency-comb generation

    NASA Astrophysics Data System (ADS)

    Dong, Mark; Winful, Herbert G.

    2016-04-01

    We present a unified approach to cascaded stimulated Brillouin scattering and frequency-comb generation in which the multitude of interacting pump, Stokes, and anti-Stokes optical fields is described by a single forward wave and a single backward wave at a single carrier frequency. The envelopes of these two waves are modulated through coupling to a single acoustic oscillation and through four-wave mixing. Starting from a single pump field, we observe the emergence of a comb of frequencies as the intensity is increased. The set of three differential equations derived here is sufficient to describe the generation of any number of Brillouin sidebands in oscillator systems that would have required hundreds of coupled equations in the standard approach. We test this approach on some published experiments and find excellent agreement with the results.

  3. Transmission comb of a distributed Bragg reflector with two surface dielectric gratings.

    PubMed

    Zhao, Xiaobo; Zhang, Yongyou; Zhang, Qingyun; Zou, Bingsuo; Schwingenschlogl, Udo

    2016-01-01

    The transmission behaviour of a distributed Bragg reector (DBR) with surface dielectric gratings on top and bottom is studied. The transmission shows a comb-like spectrum in the DBR band gap, which is explained in the Fano picture. The number density of the transmission peaks increases with increasing number of cells of the DBR, while the ratio of the average full width at half maximum to the corresponding average free spectral range, being only few percent for both transversal electric and magnetic waves, is almost invariant. The transmission peaks can be narrower than 0.1 nm and are fully separated from each other in certain wavebands. We further prove that the transmission combs are robust against randomness in the heights of the DBR layers. Therefore, the proposed structure is a candidate for an ultra-narrow-band multichannel filter or polarizer. PMID:26893069

  4. Photonic chip-based optical frequency comb using soliton Cherenkov radiation.

    PubMed

    Brasch, V; Geiselmann, M; Herr, T; Lihachev, G; Pfeiffer, M H P; Gorodetsky, M L; Kippenberg, T J

    2016-01-22

    Optical solitons are propagating pulses of light that retain their shape because nonlinearity and dispersion balance each other. In the presence of higher-order dispersion, optical solitons can emit dispersive waves via the process of soliton Cherenkov radiation. This process underlies supercontinuum generation and is of critical importance in frequency metrology. Using a continuous wave-pumped, dispersion-engineered, integrated silicon nitride microresonator, we generated continuously circulating temporal dissipative Kerr solitons. The presence of higher-order dispersion led to the emission of red-shifted soliton Cherenkov radiation. The output corresponds to a fully coherent optical frequency comb that spans two-thirds of an octave and whose phase we were able to stabilize to the sub-Hertz level. By preserving coherence over a broad spectral bandwidth, our device offers the opportunity to develop compact on-chip frequency combs for frequency metrology or spectroscopy. PMID:26721682

  5. Generation and photonic guidance of multi-octave optical-frequency combs.

    PubMed

    Couny, F; Benabid, F; Roberts, P J; Light, P S; Raymer, M G

    2007-11-16

    Ultrabroad coherent comb-like optical spectra spanning several octaves are a chief ingredient in the emerging field of attoscience. We demonstrate generation and guidance of a three-octave spectral comb, spanning wavelengths from 325 to 2300 nanometers, in a hydrogen-filled hollow-core photonic crystal fiber. The waveguidance results not from a photonic band gap but from the inhibited coupling between the core and cladding modes. The spectrum consists of up to 45 high-order Stokes and anti-Stokes lines and is generated by driving the confined gas with a single, moderately powerful (10-kilowatt) infrared laser, producing 12-nanosecond-duration pulses. This represents a reduction by six orders of magnitude in the required laser powers over previous equivalent techniques and opens up a robust and much simplified route to synthesizing attosecond pulses. PMID:18006741

  6. Dimensional metrology using the optical comb of a mode-locked laser

    NASA Astrophysics Data System (ADS)

    Jin, Jonghan

    2016-02-01

    In the field of dimensional metrology, significant technical challenges have been encountered with regard to large-scale object assembly, satellite positioning, control of the long-distance precision stage, and inspections of large steps or deep holes on semiconductor devices and multi-layered display panels. The key elements required are high speeds, a long dynamic measurable range, and good precision of measurements, and conventional methods can scarcely meet such requirements simultaneously. Promisingly, the advent of the optical comb has opened up numerous possibilities to break through practical limits by exploiting several of its unique features. These include inter-mode interference, a wide spectral bandwidth with a long coherence length and well-defined longitudinal modes. In this review, various dimensional metrological methods using the optical comb are introduced, describing their basic principles and applications in scientific as well as industrial areas.

  7. Fast interrogation of fiber Bragg grating sensors using electro-optic dual optical frequency combs

    NASA Astrophysics Data System (ADS)

    Bonilla-Manrique, O. E.; Garcia-Souto, J. A.; Martin-Mateos, P.; Jerez-Gonzalez, B.; Acedo, P.

    2015-09-01

    In this document, a FBG interrogation system based on a multimode optical source and a direct read-out is proposed for measuring fast phenomena such as vibrations and ultrasounds. The system is based on an electro-optic dual optical frequency-comb. This architecture allows the configuration of the multimode optical source parameters such as the number of modes that are within the reflected spectrum (FWHM) of the FBG. Results are presented for the dual-comb operating under optimized control when mapping these optical modes onto detectable tones of multiples of 100 kHz around a centre radiofrequency tone (40 MHz). Dynamic strain is induced onto the fiber through an actuator, which generates changes in the reflected wavelength of the FBG and in turn the modes within the reflected spectrum. The electrical signals are analyzed using fast Fourier transform algorithms allowing identification of the vibrations.

  8. Transmission comb of a distributed Bragg reflector with two surface dielectric gratings

    NASA Astrophysics Data System (ADS)

    Zhao, Xiaobo; Zhang, Yongyou; Zhang, Qingyun; Zou, Bingsuo; Schwingenschlogl, Udo

    2016-02-01

    The transmission behaviour of a distributed Bragg reector (DBR) with surface dielectric gratings on top and bottom is studied. The transmission shows a comb-like spectrum in the DBR band gap, which is explained in the Fano picture. The number density of the transmission peaks increases with increasing number of cells of the DBR, while the ratio of the average full width at half maximum to the corresponding average free spectral range, being only few percent for both transversal electric and magnetic waves, is almost invariant. The transmission peaks can be narrower than 0.1 nm and are fully separated from each other in certain wavebands. We further prove that the transmission combs are robust against randomness in the heights of the DBR layers. Therefore, the proposed structure is a candidate for an ultra-narrow-band multichannel filter or polarizer.

  9. Resonant light scattering of a laser frequency comb by a quantum dot

    NASA Astrophysics Data System (ADS)

    Konthasinghe, K.; Peiris, M.; Muller, A.

    2014-08-01

    We investigate the spectral and temporal properties of light scattered near resonantly by a single quantum dot when the incident laser field is a frequency comb consisting of a superposition of monochromatic waves equidistant in frequency. Such fields encompass those generated by, e.g., a periodically pulsed laser. A general theoretical treatment for the calculation of first- and second-order correlation functions is given which takes account of spectral diffusion through a slowly varying detuning from resonance, permitting accurate comparison with experiments. We explore the two distinct regimes in which the frequency-comb separation is either larger or smaller than the radiative decay rate. We verify the validity of our calculations by a comparison with experimental data for the case of a bichromatic field and discuss the manifestation of phase coherence between the incoming field and the scattered single-photon wave packet.

  10. Highly stable, frequency-controlled mode-locked erbium fiber laser comb

    NASA Astrophysics Data System (ADS)

    Peng, J.-L.; Ahn, H.; Shu, R.-H.; Chui, H.-C.; Nicholson, J. W.

    2007-01-01

    A mode-locked Er:fiber laser-based optical frequency comb with high stability in the repetition frequency and carrier-envelope offset (CEO) frequency is realized. The CEO beat signal was detected right after the supercontinuum generation by a compact single-beam f-2f self-referencing interferometer, which does not require further delay compensation. The stabilized repetition frequency has an out-of-loop tracking stability of 1.3×10-13/sqrt{tau} for an integration time τ less than 1000 s, which is limited by the stability of the frequency measurement system. The stabilized CEO frequency has a residual fluctuation of 0.52 mHz measured with a 1 s gate time. This is, to our knowledge, the highest tracking stability realized for fiber laser-based optical frequency comb.

  11. a New Broadband Cavity Enhanced Frequency Comb Spectroscopy Technique Using GHz Vernier Filtering.

    NASA Astrophysics Data System (ADS)

    Morville, Jérôme; Rutkowski, Lucile; Dobrev, Georgi; Crozet, Patrick

    2015-06-01

    We present a new approach to Cavity Enhanced - Direct Frequency Comb Spectroscopy where the full emission bandwidth of a Titanium:Sapphire laser is exploited at GHz resolution. The technique is based on a low-resolution Vernier filtering obtained with an appreciable -actively stabilized- mismatch between the cavity Free Spectral Range and the laser repetition rate, using a diffraction grating and a split-photodiode. This particular approach provides an immunity to frequency-amplitude noise conversion, reaching an absorption baseline noise in the 10-9 cm-1 range with a cavity finesse of only 3000. Spectra covering 1800 cm-1 (˜ 55 THz) are acquired in recording times of about 1 second, providing an absorption figure of merit of a few 10-11 cm-1/√{Hz}. Initially tested with ambient air, we report progress in using the Vernier frequency comb method with a discharge source of small radicals. Rutkowski et al, Opt. Lett., 39(23)2014

  12. Novel active comb-shaped dry electrode for EEG measurement in hairy site.

    PubMed

    Huang, Yan-Jun; Wu, Chung-Yu; Wong, Alice May-Kuen; Lin, Bor-Shyh

    2015-01-01

    Electroencephalography (EEG) is an important biopotential, and has been widely applied in clinical applications. The conventional EEG electrode with conductive gels is usually used for measuring EEG. However, the use of conductive gel also encounters with the issue of drying and hardening. Recently, many dry EEG electrodes based on different conductive materials and techniques were proposed to solve the previous issue. However, measuring EEG in the hairy site is still a difficult challenge. In this study, a novel active comb-shaped dry electrode was proposed to measure EEG in hairy site. Different form other comb-shaped or spike-shaped dry electrodes, it can provide more excellent performance of avoiding the signal attenuation, phase distortion, and the reduction of common mode rejection ratio. Even under walking motion, it can effectively acquire EEG in hairy site. Finally, the experiments for alpha rhythm and steady-state visually evoked potential were also tested to validate the proposed electrode. PMID:25137719

  13. Evanescent-wave comb spectroscopy of liquids with strongly dispersive optical fiber cavities

    NASA Astrophysics Data System (ADS)

    Avino, S.; Giorgini, A.; Salza, M.; Fabian, M.; Gagliardi, G.; De Natale, P.

    2013-05-01

    We demonstrate evanescent-wave fiber cavity-enhanced spectroscopy in the liquid phase using a near-infrared frequency comb. Exploiting strong fiber-dispersion effects, we show that liquid absorption spectra can be recorded without any external dispersive element. The fiber cavity is used both as sensor and spectrometer. The resonance modes are frequency locked to the comb teeth while the cavity photon lifetime is measured over 155 nm, from 1515 nm to 1670 nm, where absorption bands of liquid polyamines are detected as a proof of concept. Our fiber spectrometer lends itself to in situ, real-time chemical analysis in environmental monitoring, biomedical assays, and micro-opto-fluidic systems.

  14. Frequency-stabilized Yb:fiber comb with a tapered single-mode fiber

    NASA Astrophysics Data System (ADS)

    Yang, Xie; Hai-Nian, Han; Long, Zhang; Zi-Jiao, Yu; Zheng, Zhu; Lei, Hou; Li-Hui, Pang; Zhi-Yi, Wei

    2016-04-01

    We demonstrate a stable Yb:fiber frequency comb with supercontinuum generation by using a specially designed tapered single-mode fiber, in which a spectrum spanning from 500 nm to 1500 nm is produced. The carrier-envelope offset signal of the Yb:fiber comb is measured with a signal-to-noise ratio of more than 40 dB and a linewidth narrower than 120 kHz. The repetition rate and carrier-envelope offset signals are simultaneously phase locked to a microwave reference frequency. Project supported by the National Basic Research Program of China (973 Program) (Grant No. 2012CB821304) and the National Natural Science Foundation of China (Grant No. 61378040).

  15. Frequency-comb-referenced multi-wavelength profilometry for largely stepped surfaces.

    PubMed

    Hyun, Sangwon; Choi, Minah; Chun, Byung Jae; Kim, Seungman; Kim, Seung-Woo; Kim, Young-Jin

    2013-04-22

    3-D profiles of discontinuous surfaces patterned with high step structures are measured using four wavelengths generated by phase-locking to the frequency comb of an Er-doped fiber femtosecond laser stabilized to the Rb atomic clock. This frequency-comb-referenced method of multi-wavelength interferometry permits extending the phase non-ambiguity range by a factor of 64,500 while maintaining the sub-wavelength measurement precision of single-wavelength interferometry. Experimental results show a repeatability of 3.13 nm (one-sigma) in measuring step heights of 1800, 500, and 70 ?m. The proposed method is accurate enough for the standard calibration of gauge blocks and also fast to be suited for the industrial inspection of microelectronics products. PMID:23609685

  16. Photonic chip–based optical frequency comb using soliton Cherenkov radiation

    NASA Astrophysics Data System (ADS)

    Brasch, V.; Geiselmann, M.; Herr, T.; Lihachev, G.; Pfeiffer, M. H. P.; Gorodetsky, M. L.; Kippenberg, T. J.

    2016-01-01

    Optical solitons are propagating pulses of light that retain their shape because nonlinearity and dispersion balance each other. In the presence of higher-order dispersion, optical solitons can emit dispersive waves via the process of soliton Cherenkov radiation. This process underlies supercontinuum generation and is of critical importance in frequency metrology. Using a continuous wave–pumped, dispersion-engineered, integrated silicon nitride microresonator, we generated continuously circulating temporal dissipative Kerr solitons. The presence of higher-order dispersion led to the emission of red-shifted soliton Cherenkov radiation. The output corresponds to a fully coherent optical frequency comb that spans two-thirds of an octave and whose phase we were able to stabilize to the sub-Hertz level. By preserving coherence over a broad spectral bandwidth, our device offers the opportunity to develop compact on-chip frequency combs for frequency metrology or spectroscopy.

  17. Performance of a laser frequency comb calibration system with a high-resolution solar echelle spectrograph

    NASA Astrophysics Data System (ADS)

    Doerr, H.-P.; Kentischer, T. J.; Steinmetz, T.; Probst, R. A.; Franz, M.; Holzwarth, R.; Udem, Th.; Hänsch, T. W.; Schmidt, W.

    2012-09-01

    Laser frequency combs (LFC) provide a direct link between the radio frequency (RF) and the optical frequency regime. The comb-like spectrum of an LFC is formed by exact equidistant laser modes, whose absolute optical frequencies are controlled by RF-references such as atomic clocks or GPS receivers. While nowadays LFCs are routinely used in metrological and spectroscopic fields, their application in astronomy was delayed until recently when systems became available with a mode spacing and wavelength coverage suitable for calibration of astronomical spectrographs. We developed a LFC based calibration system for the high-resolution echelle spectrograph at the German Vacuum Tower Telescope (VTT), located at the Teide observatory, Tenerife, Canary Islands. To characterize the calibration performance of the instrument, we use an all-fiber setup where sunlight and calibration light are fed to the spectrograph by the same single-mode fiber, eliminating systematic effects related to variable grating illumination.

  18. A Laser Frequency Comb System for Absolute Calibration of the VTT Echelle Spectrograph

    NASA Astrophysics Data System (ADS)

    Doerr, H.-P.; Steinmetz, T.; Holzwarth, R.; Kentischer, T.; Schmidt, W.

    2012-10-01

    A wavelength calibration system based on a laser frequency comb (LFC) was developed in a co-operation between the Kiepenheuer-Institut für Sonnenphysik, Freiburg, Germany and the Max-Planck-Institut für Quantenoptik, Garching, Germany for permanent installation at the German Vacuum Tower Telescope (VTT) on Tenerife, Canary Islands. The system was installed successfully in October 2011. By simultaneously recording the spectra from the Sun and the LFC, for each exposure a calibration curve can be derived from the known frequencies of the comb modes that is suitable for absolute calibration at the meters per second level. We briefly summarize some topics in solar physics that benefit from absolute spectroscopy and point out the advantages of LFC compared to traditional calibration techniques. We also sketch the basic setup of the VTT calibration system and its integration with the existing echelle spectrograph.

  19. Transmission comb of a distributed Bragg reflector with two surface dielectric gratings

    PubMed Central

    Zhao, Xiaobo; Zhang, Yongyou; Zhang, Qingyun; Zou, Bingsuo; Schwingenschlogl, Udo

    2016-01-01

    The transmission behaviour of a distributed Bragg reector (DBR) with surface dielectric gratings on top and bottom is studied. The transmission shows a comb-like spectrum in the DBR band gap, which is explained in the Fano picture. The number density of the transmission peaks increases with increasing number of cells of the DBR, while the ratio of the average full width at half maximum to the corresponding average free spectral range, being only few percent for both transversal electric and magnetic waves, is almost invariant. The transmission peaks can be narrower than 0.1 nm and are fully separated from each other in certain wavebands. We further prove that the transmission combs are robust against randomness in the heights of the DBR layers. Therefore, the proposed structure is a candidate for an ultra-narrow-band multichannel filter or polarizer. PMID:26893069

  20. Optical properties of the iridescent organ of the comb-jellyfish Beroë cucumis (Ctenophora)

    NASA Astrophysics Data System (ADS)

    Welch, Victoria; Vigneron, Jean Pol; Lousse, Virginie; Parker, Andrew

    2006-04-01

    Using transmission electron microscopy, analytical modeling, and detailed numerical simulations, the iridescence observed from the comb rows of the ctenophore Beroë cucumis was investigated. It is shown that the changing coloration which accompanies the beating of comb rows as the animal swims can be explained by the weakly-contrasted structure of the refractive index induced by the very coherent packing of locomotory cilia. The colors arising from the narrow band-gap reflection are shown to be highly saturated and, as a function of the incidence angle, cover a wide range of the visible and ultraviolet spectrum. The high transparency of the structure at the maximal bioluminescence wavelength is also explained.

  1. Impact of dispersion on amplitude and frequency noise in a Yb-fiber laser comb.

    PubMed

    Nugent-Glandorf, Lora; Johnson, Todd A; Kobayashi, Yohei; Diddams, Scott A

    2011-05-01

    We describe a Yb-fiber-based laser comb, with a focus on the relationship between the net-cavity dispersion and frequency noise on the comb. While tuning the net-cavity dispersion from anomalous to normal, we measure the relative intensity noise, offset frequency (f(CEO)) linewidth, and the resulting frequency noise spectrum on the f(CEO). We find that the laser operating at zero net-cavity dispersion has many advantages, including an approximately 100× reduction in free-running f(CEO) linewidth and frequency noise power spectral density when compared to the normal-dispersion regime. At the zero-dispersion point, we demonstrate a phase-locked f(CEO) beat with low residual noise. PMID:21540933

  2. Mid-infrared Fourier transform spectroscopy with a broadband frequency comb.

    PubMed

    Adler, Florian; Masłowski, Piotr; Foltynowicz, Aleksandra; Cossel, Kevin C; Briles, Travis C; Hartl, Ingmar; Ye, Jun

    2010-10-11

    We present a first implementation of optical-frequency-comb-based rapid trace gas detection in the molecular fingerprint region in the mid-infrared. Near-real-time acquisition of broadband absorption spectra with 0.0056 cm(-1) maximum resolution is demonstrated using a frequency comb Fourier transform spectrometer which operates in the 2100-to-3700-cm(-1) spectral region. We achieve part-per-billion detection limits in 30 seconds of integration time for several important molecules including methane, ethane, isoprene, and nitrous oxide. Our system enables precise concentration measurements even in gas mixtures that exhibit continuous absorption bands, and it allows detection of molecules at levels below the noise floor via simultaneous analysis of multiple spectral features. PMID:20941086

  3. Adaptive frequency comb illumination for interferometry in the case of nested two-beam cavities

    SciTech Connect

    Harder, Irina; Leuchs, Gerd; Mantel, Klaus; Schwider, Johannes

    2011-09-01

    The homogeneity test of glass plates in a Fizeau interferometer is hampered by the superposition of multiple interference signals coming from the surfaces of the glass plate as well as the empty Fizeau cavity. To evaluate interferograms resulting from such nested cavities, various approaches such as the use of broadband light sources have been applied. In this paper, we propose an adaptive frequency comb interferometer to accomplish the cavity selection. An adjustable Fabry-Perot resonator is used to generate a variable frequency comb that can be matched to the length of the desired cavity. Owing to its flexibility, the number of measurements needed for the homogeneity test can be reduced to four. Furthermore, compared to approaches using a two-beam interferometer as a filter for the broadband light source, the visibility of the fringe system is considerably higher if a Fabry-Perot filter is applied.

  4. Generation of multiphoton entangled quantum states by means of integrated frequency combs.

    PubMed

    Reimer, Christian; Kues, Michael; Roztocki, Piotr; Wetzel, Benjamin; Grazioso, Fabio; Little, Brent E; Chu, Sai T; Johnston, Tudor; Bromberg, Yaron; Caspani, Lucia; Moss, David J; Morandotti, Roberto

    2016-03-11

    Complex optical photon states with entanglement shared among several modes are critical to improving our fundamental understanding of quantum mechanics and have applications for quantum information processing, imaging, and microscopy. We demonstrate that optical integrated Kerr frequency combs can be used to generate several bi- and multiphoton entangled qubits, with direct applications for quantum communication and computation. Our method is compatible with contemporary fiber and quantum memory infrastructures and with chip-scale semiconductor technology, enabling compact, low-cost, and scalable implementations. The exploitation of integrated Kerr frequency combs, with their ability to generate multiple, customizable, and complex quantum states, can provide a scalable, practical, and compact platform for quantum technologies. PMID:26965623

  5. Hierarchical, multilayered cell walls reinforced by recycled silk cocoons enhance the structural integrity of honeybee combs

    PubMed Central

    Zhang, Kai; Duan, Huiling; Karihaloo, Bhushan L.; Wang, Jianxiang

    2010-01-01

    We reveal the sophisticated and hierarchical structure of honeybee combs and measure the elastic properties of fresh and old natural honeycombs at different scales by optical microscope, environmental scanning electron microscope, nano/microindentation, and by tension and shear tests. We demonstrate that the comb walls are continuously strengthened and stiffened without becoming fragile by the addition of thin wax layers reinforced by recycled silk cocoons reminiscent of modern fiber-reinforced composite laminates. This is done to increase its margin of safety against collapse due to a temperature increase. Artificial engineering honeycombs mimic only the macroscopic geometry of natural honeycombs, but have yet to achieve the microstructural sophistication of their natural counterparts. The natural honeycombs serve as a prototype of truly biomimetic cellular materials with hitherto unattainable improvement in stiffness, strength, toughness, and thermal stability. PMID:20439765

  6. Carrier-envelope offset frequency noise analysis in Ti:sapphire frequency combs

    NASA Astrophysics Data System (ADS)

    Sutyrin, Denis V.; Poli, Nicola; Beverini, Nicolò; Tino, Guglielmo M.

    2014-12-01

    We experimentally study two Ti:sapphire optical frequency comb femtosecond regimes, respectively, with a linear and a nonlinear dependence of the carrier-envelope offset frequency (fCEO) on pump intensity. For both regimes, we study the effect of single- and multimode pump lasers on the fCEO phase noise. We demonstrate that the femtosecond regime is playing a more important role on the fCEO phase noise and stability than the pump laser type.

  7. Generation of optical frequency combs with a CaF2 resonator.

    PubMed

    Grudinin, Ivan S; Yu, Nan; Maleki, Lute

    2009-04-01

    We demonstrate optical frequency combs using the fluorite whispering gallery mode resonator as a nonlinear Kerr medium. Two regimes of generation are observed, giving the record low repetition rate of 13 GHz, equal to the cavity's free spectral range (FSR) or high repetition rates of multiples of cavity FSR. An intermediate regime was also observed. Raman lasing spectrum similar to modulation instability in fibers was observed for the first time to the best of our knowledge. PMID:19340157

  8. Aliiroseovarius pelagivivens gen. nov., sp. nov., isolated from seawater, and reclassification of three species of the genus Roseovarius as Aliiroseovarius crassostreae comb. nov., Aliiroseovarius halocynthiae comb. nov. and Aliiroseovarius sediminilitoris comb. nov.

    PubMed

    Park, Sooyeon; Park, Ji-Min; Kang, Chul-Hyung; Yoon, Jung-Hoon

    2015-08-01

    A Gram-stain-negative, non-motile, aerobic and ovoid or rod-shaped bacterium, designated GYSW-22T, was isolated from seawater off Geoje Island in the South Sea, South Korea. Strain GYSW-22T grew optimally at 25 °C, at pH 7.0-8.0 and in the presence of 1.0-2.0% (w/v) NaCl. Neighbour-joining, maximum-likelihood and maximum-parsimony phylogenetic trees based on 16S rRNA gene sequences showed that strain GYSW-22T and the type strains of Roseovarius crassostreae, Roseovarius halocynthiae and Roseovarius sediminilitoris form a coherent cluster, independent of phylogenetic lineages or clusters comprising the type strains of other species of the genus Roseovarius. Strain GYSW-22T exhibited 16S rRNA gene sequence similarities of 97.2, 96.6 and 96.3% to R. halocynthiae MA1-10T, R. crassostreae CV919-312T and R. sediminilitoris M-M10T, respectively, and of 92.6-94.7% to the type strains of other species of the genus Roseovarius. Strain GYSW-22T contained Q-10 as the predominant ubiquinone and C18 : 1ω7c as the major fatty acid. The major polar lipids were phosphatidylcholine, phosphatidylglycerol, one unidentified aminolipid and one unidentified lipid. The DNA G+C content of strain GYSW-22T was 59.0 mol% and its mean DNA-DNA relatedness value with R. halocynthiae MA1-10T was 15 %. On the basis of the data presented, we propose strain GYSW-22T represents a novel species of a new genus, Aliiroseovarius pelagivivens gen. nov., sp. nov. The type strain of the type species is GYSW-22T ( = KCTC 42459T = CECT 8811T). In this study, it is also proposed that Roseovarius crassostreae, Roseovarius halocynthiae and Roseovarius sediminilitoris be reclassified into the new genus as Aliiroseovarius crassostreae comb. nov. (type strain CV919-312T = ATCC BAA-1102T = DSM 16950T), Aliiroseovarius halocynthiae comb. nov. (type strain MA1-10T = KCTC 23462T = CCUG 60745T) and Aliiroseovarius sediminilitoris comb. nov. (type strain M-M10T = KCTC 23959T = CCUG 62413T), respectively. PMID:25964517

  9. Reclassification of [Glaciecola] lipolytica and [Aestuariibacter] litoralis in Aliiglaciecola gen. nov., as Aliiglaciecola lipolytica comb. nov. and Aliiglaciecola litoralis comb. nov., respectively.

    PubMed

    Jean, Wen Dar; Hsu, Cheng Yu; Huang, Ssu-Po; Chen, Jwo-Sheng; Lin, Saulwood; Su, Mong-Huai; Shieh, Wung Yang

    2013-08-01

    Following phylogenetic analysis based on 16S rRNA gene sequences, together with DNA G+C contents and differential chemotaxonomic and physiological characteristics, a new genus with the name Aliiglaciecola gen. nov. is proposed to more appropriately accommodate two recognized species of the genera Glaciecola and Aestuariibacter. Accordingly, [Glaciecola] lipolytica and [Aestuariibacter] litoralis should be reassigned to the novel genus as Aliiglaciecola lipolytica comb. nov. (type strain, E3(T) = JCM 15139(T) = CGMCC 1.7001(T)) and Aliiglaciecola litoralis comb. nov. (type strain, KMM 3894(T) = JCM 15896(T) = NRIC 0754(T)), respectively. Aliiglaciecola lipolytica is proposed as the type species of this new genus. Physiologically, the combined characteristics of positive reactions for nitrate reduction and growth at 4 °C and 36 °C distinguish the new genus from the genera Aestuariibacter and Glaciecola by one to three traits. Moreover, the new genus is also distinguished from the genus Glaciecola by the fatty acid profile and distinguished from the genus Aestuariibacter by the differences of major isoprenoid quinone (MK-7 vs Q-8) and DNA G+C content (40.8-43.0 mol% vs 48.0-54.0 mol%). PMID:23315410

  10. Reclassification of Methanogenium tationis and Methanogenium liminatans as Methanofollis tationis gen. nov., comb. nov. and Methanofollis liminatans comb. nov. and description of a new strain of Methanofollis liminatans

    NASA Technical Reports Server (NTRS)

    Zellner, G.; Boone, D. R.; Keswani, J.; Whitman, W. B.; Woese, C. R.; Hagelstein, A.; Tindall, B. J.; Stackebrandt, E.

    1999-01-01

    Sequencing of 16S rRNA genes and phylogenetic analysis of Methanogenium tationis DSM 2702T (OCM 43T) (T = type strain) and Methanogenium liminatans GKZPZT (= DSM 4140T) as well as other members of the family Methanomicrobiaceae revealed that both species belong to a separate line of descent within this family. In addition, a new strain of Methanogenium liminatans, strain BM1 (= DSM 10196), was isolated from a butyrate-degrading, fluidized bed reactor and characterized. Cells of both species are mesophilic, highly irregular cocci that use H2/CO2 and formate for growth and methanogenesis. In addition, Methanogenium liminatans strains GKZPZT and BM1 used 2-propanol/CO2, 2-butanol/CO2 and cyclopentanol/CO2. Both species contained diether and tetraether lipids. The polar lipids comprised amino-phosphopentanetetrol derivatives, which appear to be characteristic lipids within the family Methanomicrobiaceae. The pattern of glycolipids, phosphoglycolipids and amino-phosphoglycolipids was consistent with the assignment of these two species to a taxon within the family Methanomicrobiaceae, but also permitted them to be distinguished from other higher taxa within this family. The G+C contents of the DNA of Methanogenium tationis and Methanogenium liminatans were 54 and 60 mol% (Tm and HPLC), respectively. On the basis of the data presented, the transfer of Methanogenium tationis and Methanogenium liminatans to the genus Methanofollis gen. nov. as Methanofollis tationis comb. nov. and Methanofollis liminatans comb. nov., respectively, is proposed, with Methanofollis tationis as the type species.

  11. xComb: a cross-linked peptide database approach to protein-protein interaction analysis.

    PubMed

    Panchaud, Alexandre; Singh, Pragya; Shaffer, Scott A; Goodlett, David R

    2010-05-01

    We developed an informatic method to identify tandem mass spectra composed of chemically cross-linked peptides from those of linear peptides and to assign sequence to each of the two unique peptide sequences. For a given set of proteins the key software tool, xComb, combs through all theoretically feasible cross-linked peptides to create a database consisting of a subset of all combinations represented as peptide FASTA files. The xComb library of select theoretical cross-linked peptides may then be used as a database that is examined by a standard proteomic search engine to match tandem mass spectral data sets to identify cross-linked peptides. The database search may be conducted against as many as 50 proteins with a number of common proteomic search engines, e.g. Phenyx, Sequest, OMSSA, Mascot and X!Tandem. By searching against a peptide library of linearized, cross-linked peptides, rather than a linearized protein library, search times are decreased and the process is decoupled from any specific search engine. A further benefit of decoupling from the search engine is that protein cross-linking studies may be conducted with readily available informatics tools for which scoring routines already exist within the proteomic community. PMID:20302351

  12. Flat optical frequency comb generation and its application for optical waveform generation

    NASA Astrophysics Data System (ADS)

    Zhang, Fangzheng; Wu, Jian; Li, Yan; Lin, Jintong

    2013-03-01

    We demonstrate the generation of a flat optical frequency comb (OFC) using an electro absorption modulator (EAM) and two cascaded phase modulators (PM). Compared with previous flat OFC generation schemes using a Mach-Zehnder modulator (MZM) for amplitude gating of the phase modulated light, an EAM creates much shorter time window for amplitude gating, and more flattened OFC spectrum is obtained using EAM as an amplitude gate. In our experiment, a very flat OFC having 11 lines within 3-dB bandwidth (3.8 nm), and 40 GHz comb line spacing is generated. Besides the excellent spectral flatness, the strong time-domain linear-chirp of the generated OFC can be simply compensated by a dispersion compensation fiber (DCF) link, which is preferred for optical waveform generation based on spectral manipulation. In this paper, we also demonstrate the OFC application for generation of several optical waveforms by manipulating the amplitude and phase of the comb lines. High repetition-rate optical cosine pulse, optical pulse burst, optical square and triangle pulses are successfully generated.

  13. Dual-comb modelocked lasers: semiconductor saturable absorber mirror decouples noise stabilization.

    PubMed

    Link, Sandro M; Klenner, Alexander; Keller, Ursula

    2016-02-01

    In this paper we present the stabilization of the pulse repetition rate of dual-comb lasers using an intracavity semiconductor saturable absorber mirror (SESAM) for passive modelocking and an intracavity birefringent crystal for polarization-duplexing to obtain simultaneous emission of two modelocked beams from the same linear cavity sharing all components. Initially surprising was the observation that the cavity length adjustments to stabilize one polarization did not significantly affect the pulse repetition rate of the other. We gained insight in the underlying physics using both a semiconductor and Nd:YAG laser gain material with the conclusion that the pulse arrival timing jitter of the two beams is decoupled by the uncorrelated time delay from the saturated SESAM and becomes locked with sufficient but not too much pulse overlap. Noise stabilization is in all cases still possible for both combs. The dual-comb modelocked laser is particularly interesting for the semiconductor laser enabling the integration of gain and absorber layers within one wafer (referred to as the modelocked integrated external-cavity surface emitting laser - MIXSEL). PMID:26906767

  14. Radius of Gyration of Polystyrene Combs and Centipedes in a O Solvent

    SciTech Connect

    Terao, Ken; Farmer, Brandon S; Nakamura, Yo; Iatrou, Hermis; Hong, Kunlun; Mays, Jimmy

    2005-01-01

    The molecular weight dependence of the radii of gyration R{sub g} in a {var_theta} solvent (trans-decalin) of one regular branched comb and three regular centipede polystyrenes was studied using a gel permeation chromatography system equipped with a two-angle light scattering detector and a refractive index detector. R{sub g} in trans-decalin for each sample of particular molecular weight was about 25% smaller than that in a good solvent (tetrahydrofuran, THF). On the other hand, they are 20--40% larger than the theoretical values from the Gaussian chain model. This difference can be explained with the wormlike comb model developed by Nakamura et al. (Macromolecules 2000, 33, 8323-8328). Persistence lengths thus obtained for each sample were about half of that determined in THF solution. However, they are significantly larger than that for linear polystyrene. These results suggest that a main chain stiffening effect exists in comb polystyrenes even in a {var_theta} solvent.

  15. A wavelength-tunable fiber laser based on a twin-core fiber comb filter

    NASA Astrophysics Data System (ADS)

    Zou, Hui; Lou, Shuqin; Yin, Guolu

    2013-02-01

    A wavelength-tunable fiber laser based on a twin-core fiber (TCF) comb filter is proposed and demonstrated. The TCF comb filter is fabricated by splicing a 0.85 m long TCF between two standard single mode fibers (SMFs) and with exhibits a good linear strain characteristic with a sensitivity of 1.23 pm/μɛ. The wavelength of the laser can be linearly tuned from 1558.04 nm to 1553.62 nm by applying an axial strain to the TCF comb filter. The optical signal-to-noise ratio (OSNR) of the fiber laser reaches 45 dB. The 3 dB bandwidth is 0.02 nm. The fluctuation of the laser peak in the output power and the wavelength is less than 0.5 dB and within 0.05 nm, respectively. The fiber laser has the advantages of having a simple structure and stable operation under room temperature.

  16. Spectral distortion of dual-comb spectrometry due to repetition rate fluctuation

    NASA Astrophysics Data System (ADS)

    Hong-Lei, Yang; Hao-Yun, Wei; Yan, Li

    2016-04-01

    Dual-comb spectrometry suffers the fluctuations of parameters in combs. We demonstrate that the repetition rate is more important than any other parameter, since the fluctuation of the repetition rate leads to a change of difference in the repetition rate between both combs, consequently causing the conversion factor variation and spectral frequency misalignment. The measured frequency noise power spectral density of the repetition rate exhibits an integrated residual frequency modulation of 1.4 Hz from 1 Hz to 100 kHz in our system. This value corresponds to the absorption peak fluctuation within a root mean square value of 0.19 cm‑1 that is verified by both simulation and experimental result. Further, we can also simulate spectrum degradation as the fluctuation varies. After modifying misaligned spectra and averaging, the measured result agrees well with the simulated spectrum based on the GEISA database. Project supported by the State Key Laboratory of Precision Measurement Technology & Instruments of Tsinghua University and the Young Scientists Fund of the National Natural Science Foundation of China (Grant No. 61205147).

  17. A mummified duck-billed dinosaur with a soft-tissue cock's comb.

    PubMed

    Bell, Phil R; Fanti, Federico; Currie, Philip J; Arbour, Victoria M

    2014-01-01

    Among living vertebrates, soft tissues are responsible for labile appendages (combs, wattles, proboscides) that are critical for activities ranging from locomotion to sexual display [1]. However, soft tissues rarely fossilize, and such soft-tissue appendages are unknown for many extinct taxa, including dinosaurs. Here we report a remarkable "mummified" specimen of the hadrosaurid dinosaur Edmontosaurus regalis from the latest Cretaceous Wapiti Formation, Alberta, Canada, that preserves a three-dimensional cranial crest (or "comb") composed entirely of soft tissue. Previously, crest function has centered on the hypertrophied nasal passages of lambeosaurine hadrosaurids, which acted as resonance chambers during vocalization [2-4]. The fleshy comb in Edmontosaurus necessitates an alternative explanation most likely related to either social signaling or sexual selection [5-7]. This discovery provides the first view of bizarre, soft-tissue signaling structures in a dinosaur and provides additional evidence for social behavior. Crest evolution within Hadrosaurinae apparently culminated in the secondary loss of the bony crest at the terminal Cretaceous; however, the new specimen indicates that cranial ornamentation was in fact not lost but substituted in Edmontosaurus by a fleshy display structure. It also implies that visual display played a key role in the evolution of hadrosaurine crests and raises the possibility of similar soft-tissue structures among other dinosaurs. PMID:24332547

  18. Frequency-comb formation in doubly resonant second-harmonic generation

    NASA Astrophysics Data System (ADS)

    Leo, F.; Hansson, T.; Ricciardi, I.; De Rosa, M.; Coen, S.; Wabnitz, S.; Erkintalo, M.

    2016-04-01

    We theoretically study the generation of optical frequency combs and corresponding pulse trains in doubly resonant intracavity second-harmonic generation (SHG). We find that, despite the large temporal walk-off characteristic of realistic cavity systems, the nonlinear dynamics can be accurately and efficiently modeled using a pair of coupled mean-field equations. Through rigorous stability analysis of the system's steady-state continuous-wave solutions, we demonstrate that walk-off can give rise to an unexplored regime of temporal modulation instability. Numerical simulations performed in this regime reveal rich dynamical behaviors, including the emergence of temporal patterns that correspond to coherent optical frequency combs. We also demonstrate that the two coupled equations that govern the doubly resonant cavity behavior can, under typical conditions, be reduced to a single mean-field equation akin to that describing the dynamics of singly-resonant-cavity SHG [F. Leo et al., Phys. Rev. Lett. 116, 033901 (2016), 10.1103/PhysRevLett.116.033901]. This reduced approach allows us to derive a simple expression for the modulation instability gain, thus permitting us to acquire significant insight into the underlying physics. We anticipate that our work will have a wide impact on the study of frequency combs in emerging doubly resonant cavity SHG platforms, including quadratically nonlinear microresonators.

  19. Optical frequency comb generation based on chirping of Mach-Zehnder Modulators

    NASA Astrophysics Data System (ADS)

    Hmood, Jassim K.; Emami, Siamak D.; Noordin, Kamarul A.; Ahmad, Harith; Harun, Sulaiman W.; Shalaby, Hossam M. H.

    2015-06-01

    A new approach for the generation of an optical frequency comb, based on chirping of modulators, is proposed and numerically demonstrated. The setup includes two cascaded Mach-Zehnder Modulators (MZMs), a sinusoidal wave oscillator, and an electrical time delay. The first MZM is driven directly by a sinusoidal wave, while the second MZM is driven by a delayed replica of the sinusoidal wave. A mathematical model of the proposed system is formulated and modeled using the Matlab software. It is shown that the number of the frequency lines is directly proportional to the chirp factor. In order to achieve the highest number of frequency comb lines with the best flatness, the time delay between the driving voltages of the two MZMs is optimized. Our results reveal that at least 51 frequency lines can be observed at the output spectrum. In addition, 27 of these lines have power fluctuations of less than 1 dB. The performance of the proposed system is also simulated using a split-step numerical analysis. An optical frequency comb, with tunable frequency spacing ranging from 5 to 40 GHz, is successfully generated.

  20. Demonstration of a near-IR line-referenced electro-optical laser frequency comb for precision radial velocity measurements in astronomy

    NASA Astrophysics Data System (ADS)

    Yi, X.; Vahala, K.; Li, J.; Diddams, S.; Ycas, G.; Plavchan, P.; Leifer, S.; Sandhu, J.; Vasisht, G.; Chen, P.; Gao, P.; Gagne, J.; Furlan, E.; Bottom, M.; Martin, E. C.; Fitzgerald, M. P.; Doppmann, G.; Beichman, C.

    2016-01-01

    An important technique for discovering and characterizing planets beyond our solar system relies upon measurement of weak Doppler shifts in the spectra of host stars induced by the influence of orbiting planets. A recent advance has been the introduction of optical frequency combs as frequency references. Frequency combs produce a series of equally spaced reference frequencies and they offer extreme accuracy and spectral grasp that can potentially revolutionize exoplanet detection. Here we demonstrate a laser frequency comb using an alternate comb generation method based on electro-optical modulation, with the comb centre wavelength stabilized to a molecular or atomic reference. In contrast to mode-locked combs, the line spacing is readily resolvable using typical astronomical grating spectrographs. Built using commercial off-the-shelf components, the instrument is relatively simple and reliable. Proof of concept experiments operated at near-infrared wavelengths were carried out at the NASA Infrared Telescope Facility and the Keck-II telescope.

  1. Demonstration of a near-IR line-referenced electro-optical laser frequency comb for precision radial velocity measurements in astronomy.

    PubMed

    Yi, X; Vahala, K; Li, J; Diddams, S; Ycas, G; Plavchan, P; Leifer, S; Sandhu, J; Vasisht, G; Chen, P; Gao, P; Gagne, J; Furlan, E; Bottom, M; Martin, E C; Fitzgerald, M P; Doppmann, G; Beichman, C

    2016-01-01

    An important technique for discovering and characterizing planets beyond our solar system relies upon measurement of weak Doppler shifts in the spectra of host stars induced by the influence of orbiting planets. A recent advance has been the introduction of optical frequency combs as frequency references. Frequency combs produce a series of equally spaced reference frequencies and they offer extreme accuracy and spectral grasp that can potentially revolutionize exoplanet detection. Here we demonstrate a laser frequency comb using an alternate comb generation method based on electro-optical modulation, with the comb centre wavelength stabilized to a molecular or atomic reference. In contrast to mode-locked combs, the line spacing is readily resolvable using typical astronomical grating spectrographs. Built using commercial off-the-shelf components, the instrument is relatively simple and reliable. Proof of concept experiments operated at near-infrared wavelengths were carried out at the NASA Infrared Telescope Facility and the Keck-II telescope. PMID:26813804

  2. Demonstration of a near-IR line-referenced electro-optical laser frequency comb for precision radial velocity measurements in astronomy

    PubMed Central

    Yi, X.; Vahala, K.; Li, J.; Diddams, S.; Ycas, G.; Plavchan, P.; Leifer, S.; Sandhu, J.; Vasisht, G.; Chen, P.; Gao, P.; Gagne, J.; Furlan, E.; Bottom, M.; Martin, E. C.; Fitzgerald, M. P.; Doppmann, G.; Beichman, C.

    2016-01-01

    An important technique for discovering and characterizing planets beyond our solar system relies upon measurement of weak Doppler shifts in the spectra of host stars induced by the influence of orbiting planets. A recent advance has been the introduction of optical frequency combs as frequency references. Frequency combs produce a series of equally spaced reference frequencies and they offer extreme accuracy and spectral grasp that can potentially revolutionize exoplanet detection. Here we demonstrate a laser frequency comb using an alternate comb generation method based on electro-optical modulation, with the comb centre wavelength stabilized to a molecular or atomic reference. In contrast to mode-locked combs, the line spacing is readily resolvable using typical astronomical grating spectrographs. Built using commercial off-the-shelf components, the instrument is relatively simple and reliable. Proof of concept experiments operated at near-infrared wavelengths were carried out at the NASA Infrared Telescope Facility and the Keck-II telescope. PMID:26813804

  3. Sex, epilepsy, and epigenetics

    PubMed Central

    Qureshi, Irfan A.; Mehler, Mark F.

    2014-01-01

    Epilepsy refers to a heterogeneous group of disorders that are associated with a wide range of pathogenic mechanisms, seizure manifestations, comorbidity profiles, and therapeutic responses. These characteristics are all influenced quite significantly by sex. As with other conditions exhibiting such patterns, sex differences in epilepsy are thought to arise—at the most fundamental level—from the “organizational” and “activational” effects of sex hormones as well as from the direct actions of the sex chromosomes. However, our understanding of the specific molecular, cellular, and network level processes responsible for mediating sex differences in epilepsy remains limited. Because increasing evidence suggests that epigenetic mechanisms are involved both in epilepsy and in brain sexual dimorphism, we make the case here that analyzing epigenetic regulation will provide novel insights into the basis for sex differences in epilepsy. PMID:24998474

  4. Plant sex chromosome evolution.

    PubMed

    Charlesworth, Deborah

    2013-01-01

    It is now well established that plants have an important place in studies of sex chromosome evolution because of the repeated independent evolution of separate sexes and sex chromosomes. There has been considerable recent progress in studying plant sex chromosomes. In this review, I focus on how these recent studies have helped clarify or answer several important questions about sex chromosome evolution, and I shall also try to clarify some common misconceptions. I also outline future work that will be needed to make further progress, including testing some important ideas by genetic, molecular, and developmental approaches. Systems with different ages can clearly help show the time course of events during changes from an ancestral co-sexual state (hermaphroditism or monoecy), and I will also explain how different questions can be studied in lineages whose dioecy or sex chromosomes evolved at different times in the past. PMID:23125359

  5. Sex tourism in Thailand.

    PubMed

    Van Kerkwijk, C

    1992-01-01

    Many foreigners visit Thailand in search of sex. While long-distance tourism was long enjoyed by members of more privileged social classes, even the lower economical classes of Japan, Malaysia, Europe, America, and Australia can now afford to travel over long distances. This relatively new breed of tourist is more likely to be of lower socioeconomic and educational status and less likely to use condoms when having sex. An estimated 30,000 sex workers are active in Bangkok, of whom 7000/10,000 are females who work specifically in the tourism sector. 1/2-1/3 of the 600 commercial sex establishments in the city are visited by foreigners. Phuket, Pattaya, Koh Samui, and Chiangmai are also well-frequented by sex tourists. Overall, a large, diverse, inexpensive, and accessible commercial sex market exists in Thailand. One may meet sex workers quasi-ubiquitously and be assured to find someone capable of meeting one's sexual needs. With these attributes, Thailand strongly attracts tourists in search of sex. A certain degree of recklessness also prevails among those on vacation. Away from the peers and social mores of their native lands, tourists may engage in sexually activities without criticism. Likewise, Thai sex workers who cater to foreigners, especially females, enjoy more freedom and control in sexual relations than their peers who work among nationals. Neither single nor married women in Thailand are allowed much sexual freedom and are traditionally expected to be obliging docile, and submissive. The greater than normal personal latitude enjoyed by both sex worker and foreigner lead to more negotiation on condom use and overall lower use. As such, Thailand's commercial sex market with foreigners' involvement therein threatens to spread HIV to many other countries throughout the world. PMID:12286018

  6. Sex: Making the Right Decision

    MedlinePlus

    MENU Return to Web version Sex: Making the Right Decision Sex: Making the Right Decision What is sex? The word sex is used in several ways. It can refer ... by the penis. It also can mean what sex you were born (male or female) or physical ...

  7. Sex Determination in Papaya

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Sex determination is an intriguing system in trioecious papaya. Over the past seven decades various hypotheses, based on the knowledge and information available at the time, have been proposed to explain the genetics of the papaya's sex determination. These include a single gene with three alleles...

  8. Sex Equity Coordinator's Handbook.

    ERIC Educational Resources Information Center

    Rubenstein, Dorothy; Sillman, Donna

    This guidebook was designed to assist sex equity coordinators in the Los Angeles Community College District in promoting the recruitment, retention, and placement of students in vocational programs that are non-traditional for their sex. The guidebook's first ten chapters present: (1) outlines of relevant legislation and legal guidelines for…

  9. Single-Sex Classrooms

    ERIC Educational Resources Information Center

    Protheroe, Nancy

    2009-01-01

    Although single-sex education was once the norm in the U.S., the practice has largely been confined to private schools for more than a century. However, with the introduction of the final version of the U.S. Department of Education's so-called single-sex regulations in 2006, public schools were allowed greater flexibility to offer single-sex…

  10. Sex and America's Teenagers.

    ERIC Educational Resources Information Center

    Alan Guttmacher Inst., New York, NY.

    Although sexual activity is common among teenagers, it is not as widespread, and does not begin as early, as most adults believe. This report provides detailed data and analysis of sex among adolescents. Adolescent sexual activity is grouped in ten categories: (1) Rites of passage; (2) The context of adolescents' lives; (3) Sex among teenagers;…

  11. Sex differences in stroke

    PubMed Central

    Haast, Roy A M; Gustafson, Deborah R; Kiliaan, Amanda J

    2012-01-01

    Sex differences in stroke are observed across epidemiologic studies, pathophysiology, treatments, and outcomes. These sex differences have profound implications for effective prevention and treatment and are the focus of this review. Epidemiologic studies reveal a clear age-by-sex interaction in stroke prevalence, incidence, and mortality. While premenopausal women experience fewer strokes than men of comparable age, stroke rates increase among postmenopausal women compared with age-matched men. This postmenopausal phenomenon, in combination with living longer, are reasons for women being older at stroke onset and suffering more severe strokes. Thus, a primary focus of stroke prevention has been based on sex steroid hormone-dependent mechanisms. Sex hormones affect different (patho)physiologic functions of the cerebral circulation. Clarifying the impact of sex hormones on cerebral vasculature using suitable animal models is essential to elucidate male–female differences in stroke pathophysiology and development of sex-specific treatments. Much remains to be learned about sex differences in stroke as anatomic and genetic factors may also contribute, revealing its multifactorial nature. In addition, the aftermath of stroke appears to be more adverse in women than in men, again based on older age at stroke onset, longer prehospital delays, and potentially, differences in treatment. PMID:23032484

  12. Sex: Who Cares? Introduction.

    ERIC Educational Resources Information Center

    Liben, Lynn S.

    2000-01-01

    Presents evidence supporting claim that sex and gender are important to the explanatory as well as the descriptive goals of developmental psychology. Maintains that studying psychosocial and biological components of gender and sex helps one to develop hypotheses about causal mechanisms for developmental outcomes more generally. Introduces the…

  13. TA and Sex Stereotypes

    ERIC Educational Resources Information Center

    Roney, Anne M.

    1975-01-01

    Author discusses sex stereotypes and how they relate to transactional analysis. Thus, she claims there are striking similarities between female and male stereotypes and the Child and Adult respectively. Sex stereotypes hinder the attaining of the "I'm O.K. You're O.K." state between males and females. (SE)

  14. A laser frequency comb that enables radial velocity measurements with a precision of 1 cm s(-1).

    PubMed

    Li, Chih-Hao; Benedick, Andrew J; Fendel, Peter; Glenday, Alexander G; Kärtner, Franz X; Phillips, David F; Sasselov, Dimitar; Szentgyorgyi, Andrew; Walsworth, Ronald L

    2008-04-01

    Searches for extrasolar planets using the periodic Doppler shift of stellar spectral lines have recently achieved a precision of 60 cm s(-1) (ref. 1), which is sufficient to find a 5-Earth-mass planet in a Mercury-like orbit around a Sun-like star. To find a 1-Earth-mass planet in an Earth-like orbit, a precision of approximately 5 cm s(-1) is necessary. The combination of a laser frequency comb with a Fabry-Pérot filtering cavity has been suggested as a promising approach to achieve such Doppler shift resolution via improved spectrograph wavelength calibration, with recent encouraging results. Here we report the fabrication of such a filtered laser comb with up to 40-GHz (approximately 1-A) line spacing, generated from a 1-GHz repetition-rate source, without compromising long-term stability, reproducibility or spectral resolution. This wide-line-spacing comb, or 'astro-comb', is well matched to the resolving power of high-resolution astrophysical spectrographs. The astro-comb should allow a precision as high as 1 cm s(-1) in astronomical radial velocity measurements. PMID:18385734

  15. Echelle spectrograph calibration with a frequency comb based on a harmonically mode-locked fiber laser: a proposal

    SciTech Connect

    McFerran, J. J.

    2009-05-10

    Details for constructing an astronomical frequency comb suitable as a wavelength reference for echelle spectrographs associated with optical telescopes are outlined. The source laser for the frequency comb is a harmonically mode-locked fiber laser with a central wavelength of 1.56 {mu}m. The means of producing a repetition rate greater than 7 GHz and a peak optical power of {approx}8 kW are discussed. Conversion of the oscillator light into the visible can occur through a two-step process of (i) nonlinear conversion in periodically poled lithium niobate and (ii) spectral broadening in photonic crystal fiber. While not necessarily octave spanning in spectral range to permit the use of an f -to- 2f interferometer for offset frequency control, the frequency comb can be granted accuracy by linking the mode spacing and a comb tooth to separate frequency references. The design avoids the use of a Fabry-Perot cavity to increase the mode spacing of the frequency comb; however, the level of supermode suppression and sideband asymmetry in the fiber oscillator and in the subsequent frequency conversion stages are aspects that need to be experimentally tested.

  16. Disorder to Order Transition and Ordered Morphology of Coil-Comb Block Copolymer by Self-Consistent Field Theory

    NASA Astrophysics Data System (ADS)

    Jiang, Zhibin; Qian, Zhiyuan; Yang, Hong; Wang, Rong

    2015-08-01

    The disorder to order transition and the ordered patterns near the disordered state of coil-comb copolymer A- b-(B m + 1- g-C m ) are investigated by the self-consistent field theory. The phase diagrams of coil-comb copolymer are obtained by varying the composition of the copolymer with the side chain number m = 1, 2, and 3. The disorder to order transition is far more complex compared with the comb copolymer or linear block copolymer. As the side chain number m increases, the Flory-Huggins interaction parameter of disorder to order transition (DOT) increases and the lowest DOT occurs when the volume fractions of blocks A, B, and C are approximately equal. When one component is the minority, the disorder to order transition curve is similar with binary copolymer, but the curve shows the asymmetric property. The comb copolymer is more stable with larger side chain number m and shorter side chain. The ordered patterns from the disordered state are discussed. The results are helpful for designing coil-comb copolymers and obtaining the ordered morphology.

  17. Echelle spectrograph calibration with a frequency comb based on a harmonically mode-locked fiber laser: a proposal.

    PubMed

    McFerran, J J

    2009-05-10

    Details for constructing an astronomical frequency comb suitable as a wavelength reference for échelle spectrographs associated with optical telescopes are outlined. The source laser for the frequency comb is a harmonically mode-locked fiber laser with a central wavelength of 1.56 microm. The means of producing a repetition rate greater than 7 GHz and a peak optical power of approximately 8 kW are discussed. Conversion of the oscillator light into the visible can occur through a two-step process of (i) nonlinear conversion in periodically poled lithium niobate and (ii) spectral broadening in photonic crystal fiber. While not necessarily octave spanning in spectral range to permit the use of an f -to- 2f interferometer for offset frequency control, the frequency comb can be granted accuracy by linking the mode spacing and a comb tooth to separate frequency references. The design avoids the use of a Fabry-Perot cavity to increase the mode spacing of the frequency comb; however, the level of supermode suppression and sideband asymmetry in the fiber oscillator and in the subsequent frequency conversion stages are aspects that need to be experimentally tested. PMID:19424399

  18. Sex in Fungi

    PubMed Central

    Ni, Min; Feretzaki, Marianna; Sun, Sheng; Wang, Xuying; Heitman, Joseph

    2012-01-01

    Sexual reproduction enables genetic exchange in eukaryotic organisms as diverse as fungi, animals, plants, and ciliates. Given its ubiquity, sex is thought to have evolved once, possibly concomitant with or shortly after the origin of eukaryotic organisms themselves. The basic principles of sex are conserved, including ploidy changes, the formation of gametes via meiosis, mate recognition, and cell-cell fusion leading to the production of a zygote. Although the basic tenants are shared, sex determination and sexual reproduction occur in myriad forms throughout nature, including outbreeding systems with more than two mating types or sexes, unisexual selfing, and even examples in which organisms switch mating type. As robust and diverse genetic models, fungi provide insights into the molecular nature of sex, sexual specification, and evolution to advance our understanding of sexual reproduction and its impact throughout the eukaryotic tree of life. PMID:21942368

  19. Sex chromosome drive.

    PubMed

    Helleu, Quentin; Gérard, Pierre R; Montchamp-Moreau, Catherine

    2015-02-01

    Sex chromosome drivers are selfish elements that subvert Mendel's first law of segregation and therefore are overrepresented among the products of meiosis. The sex-biased progeny produced then fuels an extended genetic conflict between the driver and the rest of the genome. Many examples of sex chromosome drive are known, but the occurrence of this phenomenon is probably largely underestimated because of the difficulty to detect it. Remarkably, nearly all sex chromosome drivers are found in two clades, Rodentia and Diptera. Although very little is known about the molecular and cellular mechanisms of drive, epigenetic processes such as chromatin regulation could be involved in many instances. Yet, its evolutionary consequences are far-reaching, from the evolution of mating systems and sex determination to the emergence of new species. PMID:25524548

  20. Making Healthy Decisions About Sex

    MedlinePlus

    ... For Teens: How to Make Healthy Decisions About Sex Page Content Article Body Before you decide to ... alcohol or use drugs. Are You Ready for Sex? Sex can change your life and relationships. Having ...

  1. Sex and Fertility After SCI

    MedlinePlus

    Experts \\ Sex and Fertility After Spinal Cord Injury Topics Adult Injuries Spinal Cord Injury 101 Spinal Cord Injury 101 ... Spasticity, Physical Therapy-Lokomat Spasticity, Physical Therapy-Lokomat Sex and Fertility After Spinal Cord Injury Sex and ...

  2. Hepatitis C: Sex and Sexuality

    MedlinePlus

    ... with Hepatitis » Sex and Sexuality: Entire Lesson Viral Hepatitis Menu Menu Viral Hepatitis Viral Hepatitis Home For ... hepatitis C virus through sex. Can you pass hepatitis C to a sex partner? Yes, but it ...

  3. A quantitative performance measure for a clinical evaluation of comb structure removal algorithms in flexible endoscopy

    NASA Astrophysics Data System (ADS)

    Rupp, Stephan

    2008-03-01

    Modern techniques for technical inspection as well as medical diagnostics and therapy in keyhole-surgery scenarios make use of flexible endoscopes. Common to both application fields are very small natural or manmade entry points to the observed scene, as well as the complexity of the hollow itself. These make the use of rigid lens-based endoscopes or tip chip videoscopes impossible. Due to the fact that the fiber-optic image guide of a flexible endoscope introduces a comb structure to the acquired images, many research has been devoted to algorithms for an effective removal of such artifacts. Oftentimes, this research has been motivated by the fact, that the comb structure prevents an application of some well-established methods offered by the computer vision and image processing community. Unfortunately, the performance of the presented approaches are commonly visually evaluated or with respect to proprietary, non-standardized metrics. Thus, the performances of individual algorithms are hard to compare with each other. For this reasons, we propose a performance measure for fiber-optic imaging devices that has been motivated by the physics of optics. In this field, an optical system is frequently described by linear systems theory and the system's quality can be expressed by its transfer function. The determination of this transfer function has been standardized by the ISO for lens based imaging systems and represents a widely accepted measure for the quality of such systems. In this contribution, we present methods that account for fiber-optic imaging systems and thus enable a standardized performance evaluation. Finally, we demonstrate its use by comparing two recent state of the art comb structure removal algorithms, each of them being a representative of a spatial and a frequency domain method, respectively.

  4. Cascaded integrator comb filters with smoothly varying coefficients for reduced delay in synchrotron feedback loops

    NASA Astrophysics Data System (ADS)

    Schnase, A.; Nomura, M.; Tamura, F.; Yamamoto, M.; Anami, S.; Ezura, E.; Hara, K.; Ohmori, C.; Takagi, A.; Yoshii, M.

    2005-12-01

    The Rapid Cycling Synchrotron (RCS) of the J-PARC complex in Tokai, Japan, is designed to accelerate a high intensity proton beam from 181 MeV, and later 400 MeV to 3 GeV in 20 ms within the 40 ms machine cycle. The beam power up to 1 MW demands a stable beam control to avoid excessive losses and activation of the accelerator chain. The fully digital control system is based on quadrature modulation and demodulation. In the amplitude control loops standard FIR filters separate the harmonics (h=2) and (h=4) after down conversion. For the phase loops at (h=2) and (h=4), intended to damp synchrotron oscillations, the delay in a FIR filter would limit the loop stability. Cascaded integrator comb filters, also called CIC filters, provide a shorter delay because they filter the longitudinal beam signal only where it is necessary. The notches are located at multiples of the revolution frequency of the proton beam. For fixed frequency accelerator applications, digital comb filters with fixed clock frequency are widely used to improve loop stability. For variable frequency accelerator applications, as in a proton synchrotron, where the frequency swing is larger than the notch width, usually the clock frequency of the comb filter is variable and chosen to be an integer multiple of the particle revolution frequency. At J-PARC RCS, the clock frequency has to be fixed. Tracking the frequency would require a variable noninteger number of filter taps. Here we present a filter, based on the weighted output of 2 CIC filters with variable length, and one tap difference. The filter function looks like a CIC with smoothly varying coefficients, where the notches follow the revolution frequency of the proton beam. The delay of this filter is approximately half of the corresponding FIR filter, so that the phase loops have a higher stability margin.

  5. The synthesis of comb polymers containing helical polyisocyanate segments using a macromolecular titanium(IV) catalyst

    SciTech Connect

    Patten, T.E.; Novak, B.M.

    1993-12-31

    CpTiCl{sub 2}(OMMA), 1, [-OMMA = alkoxide of methyl {alpha}-(hydroxymethyl)acrylate] was synthesized from CpTiCl{sub 3} and methyl {alpha}-(hydroxymethyl)acrylate and used in the synthesis of a poly(n-hexyl isocynate) segments attached to a poly(methyl methacrylate) backbone. Methyl methacrylate and 1 were copolymerized (5% titanium containing monomer feed) using AIBN initiator at 80{degrees}C to yield a copolymer with pendant titanium alkoxide groups. Treatment of this copolymer with n-hexyl isocyanate produced the title comb polymer.

  6. Triteleia peyerimhoffi comb. n., a remarkably variable circum-Mediterranean scelionid (Hymenoptera, Platygastroidea)

    PubMed Central

    Popovici, Ovidiu Alin; Bin, Ferdinando; Masner, Lubomir; Popovici, Mariana; Notton, David

    2011-01-01

    Abstract Triteleia peyerimhoffi comb. n. (Kieffer, 1906) is redescribed taking into account its great variability and is considered the senior synonym of Triteleia dubia (Kieffer, 1908), Calliscelio lugens (Kieffer, 1910) and Triteleia striolata Kononova & Petrov, 2000, syn. n. Neotypes are designated for Triteleia dubia and Triteleia peyerimhoffi. Triteleia peyerimhoffi is a new record for Greece, France and Croatia and was reared for the first time from eggs of Orthoptera laid in the dead wood of Quercus sp. and Tilia sp. in Romania. PMID:22144859

  7. Generation of a frequency comb of squeezing in an optical parametric oscillator

    SciTech Connect

    Dunlop, A. E.; Huntington, E. H.; Harb, C. C.; Ralph, T. C.

    2006-01-15

    The multimode operation of an optical parametric oscillator (OPO) operating below threshold is calculated. We predict that squeezing can be generated in a comb that is limited only by the phase matching bandwidth of the OPO. Effects of technical noise on the squeezing spectrum are investigated. It is shown that maximal squeezing can be obtained at high frequency even in the presence of seed laser noise and cavity length fluctuations. Furthermore the spectrum obtained by detuning the laser frequency off OPO cavity resonance is calculated.

  8. Harmonic superposition for tailored optical frequency comb generation by a Mach-Zehnder modulator.

    PubMed

    Yokota, Nobuhide; Abe, Koichiro; Mieda, Shigeru; Yasaka, Hiroshi

    2016-03-01

    This Letter demonstrates tailored optical frequency comb (OFC) generation using a LiNbO3 Mach-Zehnder modulator driven by a combination of first- and second-order harmonics of the RF signal. A quasi-rectangular-shaped OFC with less than 1 dB flatness among 11 lines was experimentally obtained when a slight second-order harmonic of the RF signal (0.1 times the half-wavelength voltage) was introduced. Good agreement was obtained between the measured and calculation results for OFCs. We discuss conditions to obtain flat OFCs using this method along with details concerning OFC conversion efficiency and bandwidth. PMID:26974107

  9. Optical frequency comb based on cascading intensity modulation for optical arbitrary waveform generation

    NASA Astrophysics Data System (ADS)

    Zhou, Xin; Zheng, Xiaoping; Wen, He; Zhang, Hanyi; Guo, Yili; Zhou, Bingkun

    2010-12-01

    Optical arbitrary waveform generation (OAWG) is considered as a promising technology in microwave photonics. Line-by- line control technique for OAWG according to Fourier transform theory has been widely adopted and then Optical frequency comb (OFC) is one key point of OAWG based on this method. In the experiment, based on cascading intensity modulation, an OFC signal of nine spectral lines is generated with its excursion smaller than 2dB. And then by selecting spectral lines of interest from OFC via optical filters, 10GHz, 20GHz sinusoidal signals with low phase noise and several desirable waveforms are generated easily.

  10. Multiple trapping on a comb structure as a model of electron transport in disordered nanostructured semiconductors

    SciTech Connect

    Sibatov, R. T. Morozova, E. V.

    2015-05-15

    A model of dispersive transport in disordered nanostructured semiconductors has been proposed taking into account the percolation structure of a sample and joint action of several mechanisms. Topological and energy disorders have been simultaneously taken into account within the multiple trapping model on a comb structure modeling the percolation character of trajectories. The joint action of several mechanisms has been described within random walks with a mixture of waiting time distributions. Integral transport equations with fractional derivatives have been obtained for an arbitrary density of localized states. The kinetics of the transient current has been calculated within the proposed new model in order to analyze time-of-flight experiments for nanostructured semiconductors.

  11. Frequency-comb-referenced multi-channel fiber laser for DWDM communication.

    PubMed

    Chun, Byung Jae; Hyun, Sangwon; Kim, Seungman; Kim, Seung-Woo; Kim, Young-Jin

    2013-12-01

    We propose an all-fiber-based multi-channel optical scheme that enables simultaneous generation of multiple continuous-wave laser wavelengths with stabilization to the frequency comb of a femtosecond laser. The intention is to produce highly stable, accurate wavelength channels with immunity to environmental disturbance so as to enhance the transmission capacity of dense wavelength division multiplexing (DWDM) communications. Generated wavelengths lie over a wide spectral range of 5 THz about 1550 nm, each yielding a narrow linewidth of less than 24 kHz with an absolute position uncertainty of ~2.24 10 (10 s averaging) traceable directly to the atomic Rb clock. PMID:24514469

  12. Novel phase-locking schemes for the carrier envelope offset frequency of an optical frequency comb

    NASA Astrophysics Data System (ADS)

    Okubo, Sho; Onae, Atsushi; Hosaka, Kazumoto; Sera, Hideyuki; Inaba, Hajime; Hong, Feng-Lei

    2015-11-01

    We propose simple schemes to phase-lock the carrier envelope offset frequency (fceo) referring to the repetition rate (frep) of an optical frequency comb. We demonstrate the locking of fceo such that fceo = (1/2)frep, (1/3)frep, and (2/3)frep. The Allan deviation and signal-to-noise ratio of the coherent δ-function peak for the in-loop beat signal are 5.3 × 10-17/τ and 80-85 dB·Hz, respectively, where τ is the averaging time of the frequency measurement. These new locking schemes simplify the sign and mode-number determination in frequency measurements.

  13. Multiple trapping on a comb structure as a model of electron transport in disordered nanostructured semiconductors

    NASA Astrophysics Data System (ADS)

    Sibatov, R. T.; Morozova, E. V.

    2015-05-01

    A model of dispersive transport in disordered nanostructured semiconductors has been proposed taking into account the percolation structure of a sample and joint action of several mechanisms. Topological and energy disorders have been simultaneously taken into account within the multiple trapping model on a comb structure modeling the percolation character of trajectories. The joint action of several mechanisms has been described within random walks with a mixture of waiting time distributions. Integral transport equations with fractional derivatives have been obtained for an arbitrary density of localized states. The kinetics of the transient current has been calculated within the proposed new model in order to analyze time-of-flight experiments for nanostructured semiconductors.

  14. Dual-etalon cavity ring-down frequency-comb spectroscopy with broad band light source

    DOEpatents

    Chandler, David W; Strecker, Kevin E

    2014-04-01

    In an embodiment, a dual-etalon cavity-ring-down frequency-comb spectrometer system is described. A broad band light source is split into two beams. One beam travels through a first etalon and a sample under test, while the other beam travels through a second etalon, and the two beams are recombined onto a single detector. If the free spectral ranges ("FSR") of the two etalons are not identical, the interference pattern at the detector will consist of a series of beat frequencies. By monitoring these beat frequencies, optical frequencies where light is absorbed may be determined.

  15. A laser frequency comb featuring sub-cm/s precision for routine operation on HARPS

    NASA Astrophysics Data System (ADS)

    Probst, Rafael A.; Lo Curto, Gaspare; Avila, Gerardo; Canto Martins, Bruno L.; de Medeiros, José R.; Esposito, Massimiliano; González Hernández, Jonay I.; Hänsch, Theodor W.; Holzwarth, Ronald; Kerber, Florian; Leão, Izan C.; Manescau, Antonio; Pasquini, Luca; Rebolo-López, Rafael; Steinmetz, Tilo; Udem, Thomas; Wu, Yuanjie

    2014-07-01

    We present a re-engineered version of the laser frequency comb that has proven a few-cm/s calibration repeatability on the HARPS spectrograph during past campaigns. The new design features even better performance characteristics. The newly arranged oscillator, filter cavities and fiber injection for spectral broadening allow robust long term operation, controlled from a remote site. Its automation features enable easy operation for non-experts. The system is being prepared for installation on the HARPS spectrograph in fall of 2014, and will subsequently become available to the astronomical community.

  16. Sex Discrimination in Selecting Administrators.

    ERIC Educational Resources Information Center

    Zirkel, Perry A.; Gluckman, Ivan B.

    1984-01-01

    Discusses recent sex discrimination cases by women seeking administrative positions. Points out that women plaintiffs alleging sex bias in such cases have a difficult time proving discrimination. (MD)

  17. Characterizing the carrier-envelope offset in an optical frequency comb without traditional f-to-2f interferometry.

    PubMed

    Brochard, Pierre; Schilt, Stéphane; Wittwer, Valentin J; Südmeyer, Thomas

    2015-12-01

    We present a new method to measure the frequency noise and modulation response of the carrier-envelope offset (CEO) beat of an optical frequency comb that does not make use of the traditional f-to-2f interferometry. Instead, we use an appropriate combination of different signals to extract the contribution of the CEO frequency without directly detecting it. We present a proof-of-principle validation realized with a commercial Er:fiber frequency comb and show an excellent agreement with the results obtained using a standard f-to-2f interferometer. This approach is attractive for the characterization of novel frequency comb technologies for which self-referencing is challenging, such as semiconductor mode-locked lasers, microresonator-based systems, or GHz repetition rate lasers. PMID:26625041

  18. Quantum Dot Optical Frequency Comb Laser with Mode-Selection Technique for 1-μm Waveband Photonic Transport System

    NASA Astrophysics Data System (ADS)

    Naokatsu Yamamoto,; Kouichi Akahane,; Tetsuya Kawanishi,; Redouane Katouf,; Hideyuki Sotobayashi,

    2010-04-01

    An optical frequency comb was generated from a single quantum dot laser diode (QD-LD) in the 1-μm waveband using an Sb-irradiated InGaAs/GaAs QD active medium. A single-mode-selection technique and interference injection-seeding technique are proposed for selecting the optical mode of a QD optical frequency comb laser (QD-CML). In the 1-μm waveband, a wavelength-tunable single-mode light source and a multiple-wavelength generator of a comb with 100-GHz spacing and ultrafine teeth are successfully demonstrated by applying the optical-mode-selection techniques to the QD-CML. Additionally, by applying the single-mode-selection technique to the QD-CML, a 10-Gbps clear eye opening for multiple-wavelengths in 1-μm waveband photonic transport over a 1.5-km-long holey fiber is obtained.

  19. Quantum Dot Optical Frequency Comb Laser with Mode-Selection Technique for 1-µm Waveband Photonic Transport System

    NASA Astrophysics Data System (ADS)

    Yamamoto, Naokatsu; Akahane, Kouichi; Kawanishi, Tetsuya; Katouf, Redouane; Sotobayashi, Hideyuki

    2010-04-01

    An optical frequency comb was generated from a single quantum dot laser diode (QD-LD) in the 1-µm waveband using an Sb-irradiated InGaAs/GaAs QD active medium. A single-mode-selection technique and interference injection-seeding technique are proposed for selecting the optical mode of a QD optical frequency comb laser (QD-CML). In the 1-µm waveband, a wavelength-tunable single-mode light source and a multiple-wavelength generator of a comb with 100-GHz spacing and ultrafine teeth are successfully demonstrated by applying the optical-mode-selection techniques to the QD-CML. Additionally, by applying the single-mode-selection technique to the QD-CML, a 10-Gbps clear eye opening for multiple-wavelengths in 1-µm waveband photonic transport over a 1.5-km-long holey fiber is obtained.

  20. Stabilization of a self-referenced, prism-based, Cr:forsterite laser frequency comb using an intracavity prism

    SciTech Connect

    Tillman, Karl A.; Thapa, Rajesh; Knabe, Kevin; Wu Shun; Lim, Jinkang; Washburn, Brian R.; Corwin, Kristan L.

    2009-12-20

    The frequency comb from a prism-based Cr:forsterite laser has been frequency stabilized using intracavity prism insertion and pump power modulation. Absolute frequency measurements of a CW fiber laser stabilized to the P(13) transition of acetylene demonstrate a fractional instability of {approx}2x10{sup -11} at a 1 s gate time, limited by a commercial Global Positioning System (GPS)-disciplined rubidium oscillator. Additionally, absolute frequency measurements made simultaneously using a second frequency comb indicate relative instabilities of 3x10{sup -12} for both combs for a 1 s gate time. Estimations of the carrier-envelope offset frequency linewidth based on relative intensity noise and the response dynamics of the carrier-envelope offset to pump power changes confirm the observed linewidths.

  1. Multi-service small-cell cloud wired/wireless access network based on tunable optical frequency comb

    NASA Astrophysics Data System (ADS)

    Xiang, Yu; Zhou, Kun; Yang, Liu; Pan, Lei; Liao, Zhen-wan; Zhang, Qiang

    2015-11-01

    In this paper, we demonstrate a novel multi-service wired/wireless integrated access architecture of cloud radio access network (C-RAN) based on radio-over-fiber passive optical network (RoF-PON) system, which utilizes scalable multiple- frequency millimeter-wave (MF-MMW) generation based on tunable optical frequency comb (TOFC). In the baseband unit (BBU) pool, the generated optical comb lines are modulated into wired, RoF and WiFi/WiMAX signals, respectively. The multi-frequency RoF signals are generated by beating the optical comb line pairs in the small cell. The WiFi/WiMAX signals are demodulated after passing through the band pass filter (BPF) and band stop filter (BSF), respectively, whereas the wired signal can be received directly. The feasibility and scalability of the proposed multi-service wired/wireless integrated C-RAN are confirmed by the simulations.

  2. Sex education in Portugal.

    PubMed

    Frade, A; Vilar, D

    1991-05-01

    The article on sex education in Portugal covers background, the educational system, the clashes of the 1960's over sex education, the Committee for the Study of Sexuality and Education (CSSE), the policies, politics and social movements during the period 1974 - 1984, the discussions in Parliament, the 1988 Reform of the Educational System, the Family Planning Association (FPA) and sex education, and the future role of the FPA. It was not until the institution of the multiparity parliamentary system in 1974 that discussing social and political changes was possible, culminating in 1984 with new legislation on abortion, family planning, and sex education. School reform came in 1987/8 with the Ministry of Education primarily responsible for curricula. The 1960's brought with it the influence of the Catholic Church. Change came in the form of progressivism among Catholics who replaced dogma with dialogue and listening. Sex education was considered as preparation for marriage, but masturbation, contraception, and prostitution were also discussed. In addition, the founder of FPA chaired the CSSE in 1971 and opened up debate on sex issues and drafted a bill to establish co-education in Portuguese schools. The revolution of 1974 brought an end to censorship and brought forth a policy of developing family planning. Changed in the Family Code gave women greater equality. UNFPA supported teacher training in non-sexist education. With human reproduction included in the natural sciences, there was still no school sex education policy and contraception was only sometimes represented in the biology curriculum. The focus of FPA was on contraception and abortion. Finally in the 1980's, the first sex education programs were developed for out-of-school youth. Even though in the 1970's there were leftists groups promoting sex education, it took leftist parliamentary power to get legislation on sex education in the schools adopted. The Ministry of Education however was pressured by the Catholic Church. As in 1973, committees were formed but no action was taken. Sex education activity increased nonetheless - the first FPA document on school education prepared. In 1986 Personal and Social Education was approved by parliament providing an alternative (due to the Catholic Church) to Religious Education, but even with FPA support documents, the implementation did not begin until the end of 1990. In brief the FPA's emphasis was on the body, sexuality, sex and interpersonal relationships, and sexual reproduction. The role of FPA continues at the grass roots level in stimulating discussion; cooperating with schools, students and parents; and acting as a resource center. PMID:12343180

  3. Juvenile Sex Offenders.

    PubMed

    Ryan, Eileen P

    2016-01-01

    Public policy has tended to treat juvenile sex offenders (JSOs) as adult sex offenders in waiting, despite research that contradicts this notion. Although as a group, JSOs are more similar to general delinquents than to adult sex offenders, atypical sexual interests and sexual victimization during childhood may be a pathway for sexual offending that differentiates some JSOs from their nonsexually delinquent peers. Developmental considerations must be considered in risk assessment evaluations of these youth. This article reviews theories of sexual offending in youth, risk factors for juvenile offending and reoffending, psychopathology in JSOs, risk assessment, and treatment. PMID:26593121

  4. Effect of surface acoustic waves on the catalytic decomposition of ethanol employing a comb transducer for ultrasonic generation

    SciTech Connect

    S. J. Reese; D. H. Hurley; H.W. Rollins

    2006-04-01

    The effect of surface acoustic waves, generated on a silver catalyst using a comb transducer, on the catalytic decomposition of ethanol is examined. The comb transducer employs purely mechanical means for surface acoustic wave (SAW) transduction. Unlike interdigital SAW transducers on piezoelectric substrates, the complicating effects of heat generation due to electromechanical coupling, high electric fields between adjacent electrodes, and acoustoelectric currents are avoided. The ethanol decomposition reactions are carried out at 473 K. The rates of acetaldehyde and ethylene production are retarded when acoustic waves are applied. The rates recover to varying degrees when acoustic excitation ceases.

  5. Generation of three-octave-spanning transient Raman comb in hydrogen-filled hollow-core PCF.

    PubMed

    Tani, F; Belli, F; Abdolvand, A; Travers, J C; Russell, P St J

    2015-03-15

    A noise-seeded transient comb of Raman sidebands spanning three octaves from 180 to 2400 nm, is generated by pumping a hydrogen-filled hollow-core photonic crystal fiber with 26-μJ, 300-fs pulses at 800 nm. The pump pulses are spectrally broadened by both Kerr and Raman-related self-phase modulation (SPM), and the broadening is then transferred to the Raman lines. In spite of the high intensity, and in contrast to bulk gas-cell based experiments, neither SPM broadening nor ionization are detrimental to comb formation. PMID:25768173

  6. Generation of a phase-locked Raman frequency comb in gas-filled hollow-core photonic crystal fiber.

    PubMed

    Abdolvand, A; Walser, A M; Ziemienczuk, M; Nguyen, T; Russell, P St J

    2012-11-01

    In a relatively simple setup consisting of a microchip laser as pump source and two hydrogen-filled hollow-core photonic crystal fibers, a broad, phase-locked, purely rotational frequency comb is generated. This is achieved by producing a clean first Stokes seed pulse in a narrowband guiding photonic bandgap fiber via stimulated Raman scattering and then driving the same Raman transition resonantly with a pump and Stokes fields in a second broadband guiding kagomé-style fiber. Using a spectral interferometric technique based on sum frequency generation, we show that the comb components are phase locked. PMID:23114296

  7. Destereotyping Sex Roles

    ERIC Educational Resources Information Center

    Money, John

    1977-01-01

    Notes that it makes sense for contemporary society to relax the rigidities of its sexual stereotypes, maximizing the similarities between the sexes and the roles that men and women can share independently of the insignia between their thighs. (Author)

  8. Testicular Cancer and Sex

    MedlinePlus

    ... remove just one testicle, called an inguinal orchiectomy (IO), does not make a patient impotent and seldom ... everything from having sex the day after their IO (ouch!) all the way through having to go ...

  9. Juvenile Sex Offenders.

    PubMed

    Ryan, Eileen P; Otonichar, Joseph M

    2016-07-01

    Sexual offending by juveniles accounts for a sizable percentage of sexual offenses, especially against young children. In this article, recent research on female juvenile sex offenders (JSOs), risk factors for offending in juveniles, treatment, and the ways in which these youth may differ from general delinquents will be reviewed. Most JSOs do not go on to develop paraphilic disorders or to commit sex offenses during adulthood, and as a group, they are more similar to nonsexual offending juvenile delinquents than to adult sex offenders. Recent research has elucidated some differences between youth who commit sex offenses and general delinquents in the areas of atypical sexual interests, the use of pornography, and early sexual victimization during childhood. PMID:27222141

  10. Facies relationships and depositional environments of lower Tuscaloosa Formation reservoir sandstones in McComb and Little Creek field areas, southwest Mississippi

    SciTech Connect

    Hamilton, W.S.; Cameron, C.P.

    1986-09-01

    Detailed core and electric log studies reveal that the main producing sandstone in the McComb field area (McComb sand) was deposited as a transgressive barrier-island complex along a coastline influenced by wave action and tides. Isopachs show the McComb sand thickens to the west. This thickening pattern is consistent with regional structural maps in the McComb field area, which indicate that seaward directions lay to the west and southwest during deposition of the lower Tuscaloosa Formation. The producing sandstone in Little Creek field (Denkman Sandstone) differs from those in McComb field with respect to depositional environment and stratigraphic position. The Denkman Sandstone occupies a lower stratigraphic position in the stringer sand section than the McComb sand. The McComb sand is approximately 50-60 ft below the base of the middle marine shale formation, a unit clearly of marine origin on the basis of glauconite occurrence and fossil evidence. The Denkman Sandstone is 70-80 ft below the middle marine Tuscaloosa Formation, closer stratigraphically to the Dantzler Formation (Lower Cretaceous), which is continental in origin. The results of this study show that two major depositional facies characterize producing lower Tuscaloosa Formation sandstone reservoirs in this area: a lower fluvial sequence (Little Creek) topped by nearshore marine deposits (McComb). The study also indicates that the McComb sandstone was deposited as a transgressed barrier-island system at a time when sand supply was diminishing. Thus, the barrier complex marks the shore zone of the Upper Cretaceous marine transgression in the McComb field area.

  11. DNA combing on low-pressure oxygen plasma modified polysilsesquioxane substrates for single-molecule studies

    PubMed Central

    Sriram, K. K.; Chang, Chun-Ling; Rajesh Kumar, U.; Chou, Chia-Fu

    2014-01-01

    Molecular combing and flow-induced stretching are the most commonly used methods to immobilize and stretch DNA molecules. While both approaches require functionalization steps for the substrate surface and the molecules, conventionally the former does not take advantage of, as the latter, the versatility of microfluidics regarding robustness, buffer exchange capability, and molecule manipulation using external forces for single molecule studies. Here, we demonstrate a simple one-step combing process involving only low-pressure oxygen (O2) plasma modified polysilsesquioxane (PSQ) polymer layer to facilitate both room temperature microfluidic device bonding and immobilization of stretched single DNA molecules without molecular functionalization step. Atomic force microscopy and Kelvin probe force microscopy experiments revealed a significant increase in surface roughness and surface potential on low-pressure O2 plasma treated PSQ, in contrast to that with high-pressure O2 plasma treatment, which are proposed to be responsible for enabling effective DNA immobilization. We further demonstrate the use of our platform to observe DNA-RNA polymerase complexes and cancer drug cisplatin induced DNA condensation using wide-field fluorescence imaging. PMID:25332730

  12. Quantum Information Processing with Ytterbium Ions and a Frequency Comb in a Surface Trap

    NASA Astrophysics Data System (ADS)

    Mount, Emily; Baek, So-Young; Gaultney, Daniel; Crain, Stephen; Noek, Rachel; Maunz, Peter; Kim, Jungsang

    2012-06-01

    Microfabricated surface ion traps are one of the key components for building a trapped ion quantum information processor.These multi-segmented traps are fabricated using existing silicon processing technology and can provide the fields to store a chain of ions and shuttle ions within the trap structure. Using a surface trap microfabricated by Sandia National Laboratories [1] we trap individual Yb-171 ions and demonstrate fundamental quantum information processing primitives. Low light scatter from the trap and the use of photon arrival times during fluorescence state detection enables a state detection fidelity of 98%. High fidelity rotations of the hyperfine clock state qubit have been performed using a resonant microwave field. Furthermore, we have realized single qubit rotations using Raman transitions driven by a repetition-rate stabilized frequency comb, a prerequisite for realizing motional gates with frequency combs [2]. Microelectromechanical systems (MEMS) mirrors will be used to focus Raman laser beams on individual ions in a chain to perform single qubit gates. MEMS beam steering systems can easily be scaled to multiple beams to realize two-ion gates between arbitrary ions in the chain.[4pt] [1] D Stick et al., arXiv:1008.0990v2 2010[0pt] [2] D Hayes et al., PRL 104(14)2010

  13. Optical Comb from a Whispering Gallery Mode Resonator for Spectroscopy and Astronomy Instruments Calibration

    NASA Technical Reports Server (NTRS)

    Strekalov, Dmitry V.; Yu, Nam; Thompson, Robert J.

    2012-01-01

    The most accurate astronomical data is available from space-based observations that are not impeded by the Earth's atmosphere. Such measurements may require spectral samples taken as long as decades apart, with the 1 cm/s velocity precision integrated over a broad wavelength range. This raises the requirements specifically for instruments used in astrophysics research missions -- their stringent wavelength resolution and accuracy must be maintained over years and possibly decades. Therefore, a stable and broadband optical calibration technique compatible with spaceflights becomes essential. The space-based spectroscopic instruments need to be calibrated in situ, which puts forth specific requirements to the calibration sources, mainly concerned with their mass, power consumption, and reliability. A high-precision, high-resolution reference wavelength comb source for astronomical and astrophysics spectroscopic observations has been developed that is deployable in space. The optical comb will be used for wavelength calibrations of spectrographs and will enable Doppler measurements to better than 10 cm/s precision, one hundred times better than the current state-of-the- art.

  14. Nonlinear Cavity and Frequency Comb Radiations Induced by Negative Frequency Field Effects

    NASA Astrophysics Data System (ADS)

    Lourés, Cristian Redondo; Faccio, Daniele; Biancalana, Fabio

    2015-11-01

    Optical Kerr frequency combs (KFCs) are an increasingly important optical metrology tool with applications ranging from ultraprecise spectroscopy to time keeping. KFCs may be generated in compact resonators with extremely high quality factors. Here, we show that the same features that lead to high quality frequency combs in these resonators also lead to an enhancement of nonlinear emissions that may be identified as originating from the presence of a negative frequency (NF) component in the optical spectrum. While the negative frequency component of the spectrum is naturally always present in the real-valued optical field, it is not included in the principal theoretical model used to model nonlinear cavities, i.e., the Lugiato-Lefever equation. We therefore extend these equations in order to include the contribution of NF components and show that the predicted emissions may be studied analytically, in excellent agreement with full numerical simulations. These results are of importance for a variety of fields, such as Bose-Einstein condensates, mode-locked lasers, nonlinear plasmonics, and polaritonics.

  15. Continuous Variable Cluster State Generation over the Optical Spatial Mode Comb

    DOE PAGESBeta

    Pooser, Raphael C.; Jing, Jietai

    2014-10-20

    One way quantum computing uses single qubit projective measurements performed on a cluster state (a highly entangled state of multiple qubits) in order to enact quantum gates. The model is promising due to its potential scalability; the cluster state may be produced at the beginning of the computation and operated on over time. Continuous variables (CV) offer another potential benefit in the form of deterministic entanglement generation. This determinism can lead to robust cluster states and scalable quantum computation. Recent demonstrations of CV cluster states have made great strides on the path to scalability utilizing either time or frequency multiplexingmore » in optical parametric oscillators (OPO) both above and below threshold. The techniques relied on a combination of entangling operators and beam splitter transformations. Here we show that an analogous transformation exists for amplifiers with Gaussian inputs states operating on multiple spatial modes. By judicious selection of local oscillators (LOs), the spatial mode distribution is analogous to the optical frequency comb consisting of axial modes in an OPO cavity. We outline an experimental system that generates cluster states across the spatial frequency comb which can also scale the amount of quantum noise reduction to potentially larger than in other systems.« less

  16. Continuous Variable Cluster State Generation over the Optical Spatial Mode Comb

    SciTech Connect

    Pooser, Raphael C.; Jing, Jietai

    2014-10-20

    One way quantum computing uses single qubit projective measurements performed on a cluster state (a highly entangled state of multiple qubits) in order to enact quantum gates. The model is promising due to its potential scalability; the cluster state may be produced at the beginning of the computation and operated on over time. Continuous variables (CV) offer another potential benefit in the form of deterministic entanglement generation. This determinism can lead to robust cluster states and scalable quantum computation. Recent demonstrations of CV cluster states have made great strides on the path to scalability utilizing either time or frequency multiplexing in optical parametric oscillators (OPO) both above and below threshold. The techniques relied on a combination of entangling operators and beam splitter transformations. Here we show that an analogous transformation exists for amplifiers with Gaussian inputs states operating on multiple spatial modes. By judicious selection of local oscillators (LOs), the spatial mode distribution is analogous to the optical frequency comb consisting of axial modes in an OPO cavity. We outline an experimental system that generates cluster states across the spatial frequency comb which can also scale the amount of quantum noise reduction to potentially larger than in other systems.

  17. Femtosecond frequency comb measurement of absolute frequencies and hyperfine coupling constants in cesium vapor

    SciTech Connect

    Stalnaker, Jason E.; Mbele, Vela; Gerginov, Vladislav; Fortier, Tara M.; Diddams, Scott A.; Hollberg, Leo; Tanner, Carol E.

    2010-04-15

    We report measurements of absolute transition frequencies and hyperfine coupling constants for the 8S{sub 1/2}, 9S{sub 1/2}, 7D{sub 3/2}, and 7D{sub 5/2} states in {sup 133}Cs vapor. The stepwise excitation through either the 6P{sub 1/2} or 6P{sub 3/2} intermediate state is performed directly with broadband laser light from a stabilized femtosecond laser optical-frequency comb. The laser beam is split, counterpropagated, and focused into a room-temperature Cs vapor cell. The repetition rate of the frequency comb is scanned and we detect the fluorescence on the 7P{sub 1/2,3/2{yields}}6S{sub 1/2} branches of the decay of the excited states. The excitations to the different states are isolated by the introduction of narrow-bandwidth interference filters in the laser beam paths. Using a nonlinear least-squares method we find measurements of transition frequencies and hyperfine coupling constants that are in agreement with other recent measurements for the 8S state and provide improvement by 2 orders of magnitude over previously published results for the 9S and 7D states.

  18. Environmental-adaptability analysis of an all polarization-maintaining fiber-based optical frequency comb.

    PubMed

    Feng, Ye; Xu, Xin; Hu, Xiaohong; Liu, Yuanshan; Wang, Yishan; Zhang, Wei; Yang, Zhi; Duan, Lina; Zhao, Wei; Cheng, Zhao

    2015-06-29

    We demonstrate an all polarization-maintaining (PM) fiber-based optical frequency comb and provide the detailed environmental stability analysis results. The frequency comb has been built by commercial available PM fiber completely, and its static uncertainty in optical domain is 350 Hz in 1 s when referenced to a low noise oven controlled crystal oscillator. The acoustic resonant frequencies of the system have been measured. It is proved that acoustic-vibration induced phase noise could be eliminated by low pass vibration-isolation structure. Further, the existence of the optimum working temperature is illustrated. At this temperature (289.6 K), the out-loop integrated phase noise of f(r) and the temperature-drift induced instability of f(CEO) reach the lowest level 31.6 μrad and 0 kHz/(mW∙K) respectively. Finally, the system is proved to be stable under different humidity (18% ~80%) by a 240-day-long record of the f(CEO). PMID:26191762

  19. Lithium battery with solid polymer electrolyte based on comb-like copolymers

    NASA Astrophysics Data System (ADS)

    Daigle, Jean-Christophe; Vijh, Ashok; Hovington, Pierre; Gagnon, Catherine; Hamel-Pâquet, Julie; Verreault, Serge; Turcotte, Nancy; Clément, Daniel; Guerfi, Abdelbast; Zaghib, Karim

    2015-04-01

    In this paper we report on the synthesis of comb-like copolymers as solid polymer electrolytes (SPE). The synthesis involved anionic polymerization of styrene (St) and 4-vinylanisole (VA) as the followed by grafting of poly(ethylene glycol) monomethyl ether methacrylate (PEGMA) by Atom Transfer Radical Polymerization (ATRP). The comb-like copolymer's structure was analyzed by Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance (NMR) and gel permeation chromatography (GPC). The membranes were made by solvent casting and the morphologies were analyzed by atomic forces microscopy (AFM) and scanning electron microscopy (SEM). We observed that a nano and micro phase separation occurs which improves ionic conductivity. The ionic conductivities were determined by AC Impedance, which showed that the SPEs have good conductivities (10-5 Scm-1) at room temperature owing to the negligible values (<10 kJ mol-1) of the activation energies for conductivity. The batteries with these polymers exhibit a capacity of 146 mAh g-1 at C/24, and no evidence of degradation after intense cycling was observed. However, poor cycle life was observed at C/6 and C/3, which is a consequence of several factors. We partially explain that behavior by arguing that whereas PEO lightly "solvates" Li+ thus slowing Li-ion mobility, and PEGMA chains "solvate" Li ions too strongly, trapping and inhibiting their mobility.

  20. Genomic data do not support comb jellies as the sister group to all other animals.

    PubMed

    Pisani, Davide; Pett, Walker; Dohrmann, Martin; Feuda, Roberto; Rota-Stabelli, Omar; Philippe, Hervé; Lartillot, Nicolas; Wörheide, Gert

    2015-12-15

    Understanding how complex traits, such as epithelia, nervous systems, muscles, or guts, originated depends on a well-supported hypothesis about the phylogenetic relationships among major animal lineages. Traditionally, sponges (Porifera) have been interpreted as the sister group to the remaining animals, a hypothesis consistent with the conventional view that the last common animal ancestor was relatively simple and more complex body plans arose later in evolution. However, this premise has recently been challenged by analyses of the genomes of comb jellies (Ctenophora), which, instead, found ctenophores as the sister group to the remaining animals (the "Ctenophora-sister" hypothesis). Because ctenophores are morphologically complex predators with true epithelia, nervous systems, muscles, and guts, this scenario implies these traits were either present in the last common ancestor of all animals and were lost secondarily in sponges and placozoans (Trichoplax) or, alternatively, evolved convergently in comb jellies. Here, we analyze representative datasets from recent studies supporting Ctenophora-sister, including genome-scale alignments of concatenated protein sequences, as well as a genomic gene content dataset. We found no support for Ctenophora-sister and conclude it is an artifact resulting from inadequate methodology, especially the use of simplistic evolutionary models and inappropriate choice of species to root the metazoan tree. Our results reinforce a traditional scenario for the evolution of complexity in animals, and indicate that inferences about the evolution of Metazoa based on the Ctenophora-sister hypothesis are not supported by the currently available data. PMID:26621703

  1. Carrier-envelope phase- and spectral control of fractional high-harmonic combs

    NASA Astrophysics Data System (ADS)

    Raith, Philipp; Ott, Christian; Meyer, Kristina; Kaldun, Andreas; Laux, Martin; Ceci, Matteo; Anderson, Christopher P.; Pfeifer, Thomas

    2013-11-01

    We experimentally and numerically control high-harmonic generation (HHG) by time delaying variable segments of a few-cycle driving laser spectrum. In this configuration combs of fractional high harmonics can be produced by interference of two temporally spaced attosecond pulse trains. We explain the observed beating of the high-harmonic intensity with the time delay and study the influence of the spectral segmentation on the high harmonics. By the implementation of additional carrier-envelope phase (CEP) control, we extend the control configuration and demonstrate independent multi-parameter controllability of HHG purely enabled by the CEP and the time delay between two spectral segments. We present how specific properties of the fractional harmonics can be optimized. Analyzing the measured fractional harmonic combs by a spectral interferometry method, we find that the relative phase between the two contributing attosecond pulse trains can be freely set by the CEP of the driving laser field. We also discuss how, in the future, this method can be applied to simultaneously measure transient dispersion and absorption in the extreme ultraviolet spectral region.

  2. A novel large displacement electrostatic actuator: pre-stress comb-drive actuator

    NASA Astrophysics Data System (ADS)

    Chiou, J. C.; Lin, Y. J.

    2005-09-01

    This investigation proposes a novel large vertical displacement electrostatic actuator, called the pre-stress comb-drive actuator (PCA), which exhibits no pull-in and no hysteresis characteristics. The proposed PCA consists of a set of comb fingers fabricated along the composite beam and substrate. One end of the composite beam is clamped to the anchor, whereas the other end is elevated vertically by the residual stress. The actuation occurs when the electrostatic force, induced by the fringe effect, pulls the composite beam downward to the substrate. A post-heat treatment process was employed to increase the initial lift height of the PCA to obtain a large actuation stroke. A mathematical model, based on a newly developed modeling approach, is introduced to estimate the static characteristic of the PCA. A PCA was fabricated using the PolyMUMPs process based on the proposed design concept. Following packaging and applying a post-heat treatment process, a 110 µm initial tip height and a 90 µm vertical motion range were achieved. Neither pull-in nor hysteresis was observed. The simulation results were closely matched with the observations. This work also studies the frequency response and measurement of the maximum vibration of the PCA.

  3. Direct frequency comb optical frequency standard based on two-photon transitions of thermal atoms

    PubMed Central

    Zhang, S. Y.; Wu, J. T.; Zhang, Y. L.; Leng, J. X.; Yang, W. P.; Zhang, Z. G.; Zhao, J. Y.

    2015-01-01

    Optical clocks have been the focus of science and technology research areas due to their capability to provide highest frequency accuracy and stability to date. Their superior frequency performance promises significant advances in the fields of fundamental research as well as practical applications including satellite-based navigation and ranging. In traditional optical clocks, ultrastable optical cavities, laser cooling and particle (atoms or a single ion) trapping techniques are employed to guarantee high stability and accuracy. However, on the other hand, they make optical clocks an entire optical tableful of equipment, and cannot work continuously for a long time; as a result, they restrict optical clocks used as very convenient and compact time-keeping clocks. In this article, we proposed, and experimentally demonstrated, a novel scheme of optical frequency standard based on comb-directly-excited atomic two-photon transitions. By taking advantage of the natural properties of the comb and two-photon transitions, this frequency standard achieves a simplified structure, high robustness as well as decent frequency stability, which promise widespread applications in various scenarios. PMID:26459877

  4. Self-referenceable frequency comb from an ultrafast thin disk laser.

    PubMed

    Saraceno, Clara J; Pekarek, Selina; Heckl, Oliver H; Baer, Cyrill R E; Schriber, Cinia; Golling, Matthias; Beil, Kolja; Kränkel, Christian; Huber, Günter; Keller, Ursula; Südmeyer, Thomas

    2012-04-23

    We present the first measurement of the carrier envelope offset (CEO) frequency of an ultrafast thin disk laser (TDL). The TDL used for this proof-of-principle experiment was based on the gain material Yb:Lu(2)O(3) and delivered 7 W of average power in 142-fs pulses, which is more than two times shorter than previously realized with this material. Using only 65 mW of the output of the laser, we generated a coherent octave-spanning supercontinuum (SC) in a highly nonlinear photonic crystal fiber (PCF). We detected the CEO beat signal using a standard f-to-2f interferometer, achieving a signal-to-noise ratio of >25 dB (3 kHz resolution bandwidth). The CEO frequency was tunable with the pump current with a slope of 33 kHz/mA. This result opens the door towards high-power frequency combs from unamplified oscillators. Furthermore, it confirms the suitability of these sources for future intralaser extreme nonlinear optics experiments such as high harmonic generation and VUV frequency comb generation from compact sources. PMID:22535056

  5. High flatness optical frequency comb generator based on the chirping of modulators

    NASA Astrophysics Data System (ADS)

    Qu, Kun; Zhao, Shanghong; Liang, Dan Ya; Zhu, Zihang; Dong, Chen; Li, Xuan

    2016-04-01

    A novel scheme for generation of an optical frequency comb (OFC) based on the chirping of two cascaded modulators is proposed. The first modulator is a dual-electrode Mach-Zehnder modulator (MZM), while the other modulator is an integrated MZM composed of two parallel MZMs that increases the number of comb lines. Our modified scheme can generate a large number of frequency lines with excellent flatness by simply modifying the chirp factor, and it is shown that up to 54 frequency lines could be observed. Theoretical analysis and simulation results show that under the variety of conditions that can be used in this scheme, the power fluctuations of the OFC lines are less than 0.5 dB in all cases; these results demonstrate the robustness of our scheme and verify its good accuracy and high stability with perfect flatness. Additionally, our modified scheme has the merit of tunable frequency spacing, which is practical for experimental realization of the OFC.

  6. Hardware comb filter enhances dynamic range and noise performance of sensors in noisy environments

    NASA Astrophysics Data System (ADS)

    Prance, H.; Prance, R. J.; Stiffell, P. B.

    2007-07-01

    We present the results of combining a hardware implementation of an analog comb filter with an ultralow noise electromagnetic sensor. The comb filter is designed to attenuate mains related interference, at either 50 or 60Hz, and related harmonics. The sensor chosen for this work is an induction magnetometer, but the method is applicable to any low noise high dynamic range sensor. The resultant system, in this case, uses only a single coil, not a gradiometric configuration, thus providing a magnetometer capable of sensing field as opposed to field gradient. This combination of filter and sensor allows additional gain to be added and the full sensitivity of the system to be achieved, previously only realized in an electromagnetically screened room. At the same time, the high dynamic range, low noise performance, and original bandwidth of the sensor are maintained. The technique is illustrated by using the system in an urban environment to observe Schumann resonance phenomena. This approach to acquiring small signals in a noisy environment is compared with conventional analog filter and digital signal processing techniques.

  7. Direct frequency comb optical frequency standard based on two-photon transitions of thermal atoms

    NASA Astrophysics Data System (ADS)

    Zhang, S. Y.; Wu, J. T.; Zhang, Y. L.; Leng, J. X.; Yang, W. P.; Zhang, Z. G.; Zhao, J. Y.

    2015-10-01

    Optical clocks have been the focus of science and technology research areas due to their capability to provide highest frequency accuracy and stability to date. Their superior frequency performance promises significant advances in the fields of fundamental research as well as practical applications including satellite-based navigation and ranging. In traditional optical clocks, ultrastable optical cavities, laser cooling and particle (atoms or a single ion) trapping techniques are employed to guarantee high stability and accuracy. However, on the other hand, they make optical clocks an entire optical tableful of equipment, and cannot work continuously for a long time; as a result, they restrict optical clocks used as very convenient and compact time-keeping clocks. In this article, we proposed, and experimentally demonstrated, a novel scheme of optical frequency standard based on comb-directly-excited atomic two-photon transitions. By taking advantage of the natural properties of the comb and two-photon transitions, this frequency standard achieves a simplified structure, high robustness as well as decent frequency stability, which promise widespread applications in various scenarios.

  8. Direct frequency comb optical frequency standard based on two-photon transitions of thermal atoms.

    PubMed

    Zhang, S Y; Wu, J T; Zhang, Y L; Leng, J X; Yang, W P; Zhang, Z G; Zhao, J Y

    2015-01-01

    Optical clocks have been the focus of science and technology research areas due to their capability to provide highest frequency accuracy and stability to date. Their superior frequency performance promises significant advances in the fields of fundamental research as well as practical applications including satellite-based navigation and ranging. In traditional optical clocks, ultrastable optical cavities, laser cooling and particle (atoms or a single ion) trapping techniques are employed to guarantee high stability and accuracy. However, on the other hand, they make optical clocks an entire optical tableful of equipment, and cannot work continuously for a long time; as a result, they restrict optical clocks used as very convenient and compact time-keeping clocks. In this article, we proposed, and experimentally demonstrated, a novel scheme of optical frequency standard based on comb-directly-excited atomic two-photon transitions. By taking advantage of the natural properties of the comb and two-photon transitions, this frequency standard achieves a simplified structure, high robustness as well as decent frequency stability, which promise widespread applications in various scenarios. PMID:26459877

  9. Smooth and flat phase-locked Kerr frequency comb generation by higher order mode suppression.

    PubMed

    Huang, S-W; Liu, H; Yang, J; Yu, M; Kwong, D-L; Wong, C W

    2016-01-01

    High-Q microresonator is perceived as a promising platform for optical frequency comb generation, via dissipative soliton formation. In order to achieve a higher quality factor and obtain the necessary anomalous dispersion, multi-mode waveguides were previously implemented in Si3N4 microresonators. However, coupling between different transverse mode families in multi-mode waveguides results in periodic disruption of dispersion and quality factor, and consequently causes perturbation to dissipative soliton formation and amplitude modulation to the corresponding spectrum. Careful choice of pump wavelength to avoid the mode crossing region is thus critical in conventional Si3N4 microresonators. Here, we report a novel design of Si3N4 microresonator in which single-mode operation, high quality factor, and anomalous dispersion are attained simultaneously. The novel microresonator is consisted of uniform single-mode waveguides in the semi-circle region, to eliminate bending induced mode coupling, and adiabatically tapered waveguides in the straight region, to avoid excitation of higher order modes. The intrinsic quality factor of the microresonator reaches 1.36 × 10(6) while the group velocity dispersion remains to be anomalous at -50 fs(2)/mm. With this novel microresonator, we demonstrate that broadband phase-locked Kerr frequency combs with flat and smooth spectra can be generated by pumping at any resonances in the optical C-band. PMID:27181420

  10. Ultra-Low Phase Noise, High Resolution Spectrometer Using Comb-Assisted Quantum Cascade Lasers

    NASA Astrophysics Data System (ADS)

    Mills, Andrew A.; Mohr, Christian; Jiang, Jie; Gatti, Davide; Marangoni, Marco; Gianfrani, Livio; Hartl, Ingmar; Fermann, Martin

    2013-06-01

    In recent years, optical frequency combs have been used extensively to stabilize solid state cw lasers for high resolution spectroscopy, enabling the acquisition of absorption profiles of a gas sample with an absolutely calibrated, repeatable and linear frequency axis. This uniquely defined and repeatable frequency axis allows for the retrieval of highly accurate and traceable spectroscopic parameters and the ability to obtain physical insights regarding the influence of collisional processes on the absorption line shapes. The highly accurate frequency axis has can be used in precision spectroscopy applications such as resolving hyperfine transitions or cavity enhanced spectroscopy for trace gas detection. To simplify such precision spectroscopy systems in the future, the use of quantum cascade lasers (QCL) as a spectroscopic tool is highly desired. Here we report on the precision phase locking of a 9 μm QCL to a 2 μm low-noise thulium frequency comb. Utilizing a coherent lock with a MHz-level feedback bandwidth, we line narrow a QCL with a 1 MHz linewidth and achieve an in-loop beatnote measurement with 70 dB S/N at 1 Hz RBW. As an application, we demonstrate the interrogation of sub-Doppler features of ammonia spectra at 9 μm. It is expected that the system is further compatible with line narrowing of widely tunable external cavity QCL's, opening new measurement avenues in precision spectroscopy.

  11. Nested folded-beam suspensions with low longitudinal stiffness for comb-drive actuators

    NASA Astrophysics Data System (ADS)

    Hou, Max T.; Huang, Ming-Xian; Chang, Chao-Min

    2014-12-01

    Nested folded-beam suspensions with a low longitudinal spring constant and a high lateral spring constant have been used in comb-drive actuators. In the new design, every two flexible beams and two stiff members form a parallelogram flexure, which is considered as an element of the nested folded-beam suspension. A set of these flexures of increasing size were placed one outside another to compose a nested structure. In this way, a serial mechanical connection between adjacent parallelogram flexures was formed; thus, a longer output stroke was obtained by combining the stroke displacements of all flexures in an additive fashion. The designed suspensions were theoretically analyzed and numerically simulated. Furthermore, comb-drive actuators with conventional and new suspensions were fabricated and tested to verify the predicted function. In the testing cases, the longitudinal spring constants of suspensions with two (conventional), three and four parallelogram flexures on each side were measured as 2.77, 1.75 and 1.36?N?m-1. The ratio among these three values was approximately 6:4:3, which is consistent with the theoretical predictions and simulation results. Microfabricated folded beams in series were achieved.

  12. Extremely high-accuracy correction of air refractive index using two-colour optical frequency combs.

    PubMed

    Wu, Guanhao; Takahashi, Mayumi; Arai, Kaoru; Inaba, Hajime; Minoshima, Kaoru

    2013-01-01

    Optical frequency combs have become an essential tool for distance metrology, showing great advantages compared with traditional laser interferometry. However, there is not yet an appropriate method for air refractive index correction to ensure the high performance of such techniques when they are applied in air. In this study, we developed a novel heterodyne interferometry technique based on two-colour frequency combs for air refractive index correction. In continuous 500-second tests, a stability of 1.0 10(-11) was achieved in the measurement of the difference in the optical distance between two wavelengths. Furthermore, the measurement results and the calculations are in nearly perfect agreement, with a standard deviation of 3.8 10(-11) throughout the 10-hour period. The final two-colour correction of the refractive index of air over a path length of 61 m was demonstrated to exhibit an uncertainty better than 1.4 10(-8), which is the best result ever reported without precise knowledge of environmental parameters. PMID:23719387

  13. Genomic data do not support comb jellies as the sister group to all other animals

    PubMed Central

    Pisani, Davide; Pett, Walker; Dohrmann, Martin; Feuda, Roberto; Rota-Stabelli, Omar; Philippe, Hervé; Lartillot, Nicolas; Wörheide, Gert

    2015-01-01

    Understanding how complex traits, such as epithelia, nervous systems, muscles, or guts, originated depends on a well-supported hypothesis about the phylogenetic relationships among major animal lineages. Traditionally, sponges (Porifera) have been interpreted as the sister group to the remaining animals, a hypothesis consistent with the conventional view that the last common animal ancestor was relatively simple and more complex body plans arose later in evolution. However, this premise has recently been challenged by analyses of the genomes of comb jellies (Ctenophora), which, instead, found ctenophores as the sister group to the remaining animals (the “Ctenophora-sister” hypothesis). Because ctenophores are morphologically complex predators with true epithelia, nervous systems, muscles, and guts, this scenario implies these traits were either present in the last common ancestor of all animals and were lost secondarily in sponges and placozoans (Trichoplax) or, alternatively, evolved convergently in comb jellies. Here, we analyze representative datasets from recent studies supporting Ctenophora-sister, including genome-scale alignments of concatenated protein sequences, as well as a genomic gene content dataset. We found no support for Ctenophora-sister and conclude it is an artifact resulting from inadequate methodology, especially the use of simplistic evolutionary models and inappropriate choice of species to root the metazoan tree. Our results reinforce a traditional scenario for the evolution of complexity in animals, and indicate that inferences about the evolution of Metazoa based on the Ctenophora-sister hypothesis are not supported by the currently available data. PMID:26621703

  14. Sex Bias in Research Design.

    ERIC Educational Resources Information Center

    Grady, Kathleen E.

    1981-01-01

    Presents feminist criticisms of selected aspects of research methods in psychology. Reviews data relevant to sex bias in topic selection, subject selection and single-sex designs, operationalization of variables, testing for sex differences, and interpretation of results. Suggestions for achieving more "sex fair" research methods are discussed.…

  15. Somatic sex determination.

    PubMed Central

    Zarkower, David

    2006-01-01

    C. elegans occurs in two natural sexes, the XX hermaphrodite and the XO male, which differ extensively in anatomy, physiology, and behavior. All somatic differences between the sexes result from the differential activity of a "global" sex determination regulatory pathway. This pathway also controls X chromosome dosage compensation, which is coordinated with sex determination by the action of the three SDC proteins. The SDC proteins control somatic and germline sex by transcriptional repression of the her-1 gene. HER-1 is a secreted protein that controls a regulatory module consisting of a transmembrane receptor, TRA-2, three intracellular FEM proteins, and the zinc finger transcription factor TRA-1. The molecular workings of this regulatory module are still being elucidated. Similarity of TRA-2 to patched receptors and of TRA-1 to GLI proteins suggests that parts of the global pathway originally derived from a Hedgehog signaling pathway. TRA-1 controls all aspects of somatic sexual differentiation, presumably by regulating a variety of tissue- and cell-specific downstream targets, including the cell death regulator EGL-1 and the male sexual regulator MAB-3. Sex determination evolves rapidly, and conservation of sexual regulators between phyla has been elusive. An apparent exception involves DM domain proteins, including MAB-3, which control sexual differentiation in nematodes, arthropods, and vertebrates. Important issues needing more study include the detailed molecular mechanisms of the global pathway, the identities of additional sexual regulators acting in the global pathway and downstream of TRA-1, and the evolutionary history of the sex determination pathway. Recently developed genetic and genomic technologies and comparative studies in divergent species have begun to address these issues. PMID:18050479

  16. The Snygg-Combs Phenomenological Theory of Perception and Its Implications for Adult Education Theory and Practice.

    ERIC Educational Resources Information Center

    Russell, John Tennyson

    The Snygg-Combs theory of perception was examined as to its utility in subsuming and explaining the interaction of common elements found among variables in adult teaching and learning situations. Answers were sought to 15 questions regarding the origins, essential characteristics, criticisms, and methodologies of the theory; its philosophical…

  17. Mid-infrared optical frequency combs at 2.5 μm based on crystalline microresonators

    PubMed Central

    Wang, C. Y.; Herr, T.; Del’Haye, P.; Schliesser, A.; Hofer, J.; Holzwarth, R.; Hänsch, T. W.; Picqué, N.; Kippenberg, T. J.

    2013-01-01

    The mid-infrared spectral range (λ~2–20 μm) is of particular importance as many molecules exhibit strong vibrational fingerprints in this region. Optical frequency combs—broadband optical sources consisting of equally spaced and mutually coherent sharp lines—are creating new opportunities for advanced spectroscopy. Here we demonstrate a novel approach to create mid-infrared optical frequency combs via four-wave mixing in a continuous-wave pumped ultra-high Q crystalline microresonator made of magnesium fluoride. Careful choice of the resonator material and design made it possible to generate a broadband, low-phase noise Kerr comb at λ=2.5 μm spanning 200 nm (≈10 THz) with a line spacing of 100 GHz. With its distinguishing features of compactness, efficient conversion, large mode spacing and high power per comb line, this novel frequency comb source holds promise for new approaches to molecular spectroscopy and is suitable to be extended further into the mid-infrared. PMID:23299895

  18. Off-pump suture repair of left ventricular rupture utilizing TachoComb sheet: a case report and literature review

    PubMed Central

    2013-01-01

    A 70-year-old woman was admitted to our institution with acute myocardial infarction. Coronary angiography demonstrated total occlusion of the left anterior descending artery, which was successfully revascularized. Four days later, the patient suddenly went into shock. The subsequent emergency operation revealed a blowout rupture of the left ventricular free wall. Several TachoComb (CSL Behring, Tokyo, Japan) sheets were applied to control bleeding and avoid the need for a cardiopulmonary bypass. Horizontal mattress sutures were used in combination with a pair of Teflon felt strips for reinforcement. The combination of TachoComb sheets and sutures is a novel hybrid method and an effective life-saving procedure for the treatment of left ventricular blowout ruptures. This approach avoids the need for a cardiopulmonary bypass. Sutureless repairs with TachoComb sheet achieve rapid hemostasis without the need for cardiopulmonary bypass. This stabilizes patient hemodynamics immediately and preserves the fragile myocardium. This allows emergency room physicians to open the chest and apply the TachoComb sheet to stabilize the patient before the cardiac surgeons arrive at the operating room. This technique will be very useful in emergency situations. PMID:23890151

  19. Plastic (wire-combed) grooving of a slip-formed concrete runway overlay at Patrick Henry Airport: An initial evaluation

    NASA Technical Reports Server (NTRS)

    Marlin, E. C.; Horne, W. B.

    1977-01-01

    A wire-comb technique is described for transversely grooving the surface of a freshly laid (plastic state) slip-formed concrete overlay installed at Patrick Henry Airport. This method of surface texturing yields better water drainage and pavement skid resistance than that obtained with an older conventional burlap drag concrete surface treatment installed on an adjacent portion of the runway.

  20. Reclassification of Wolbachia persica as Francisella persica comb. nov. and emended description of the family Francisellaceae.

    PubMed

    Larson, Marilynn A; Nalbantoglu, Ufuk; Sayood, Khalid; Zentz, Emily B; Cer, Regina Zing; Iwen, Peter C; Francesconi, Stephen C; Bishop-Lilly, Kimberly A; Mokashi, Vishwesh P; Sjöstedt, Anders; Hinrichs, Steven H

    2016-03-01

    The taxonomic status of the bacterium Wolbachia persica is described, and based on the evidence presented, transfer of this species to the genus Francisella as Francisella persica comb. nov. is proposed. This reclassification is supported by data generated from genomic comparisons of W. persica ATCC VR-331T ( = FSC845T = DSM 101678T) to other near neighbours, including Francisella tularensis subsp. novicida. The full-length 16S rRNA gene sequence of strain ATCC VR-331T had 98.5 % nucleotide identity to the cognate gene in F. tularensis, with the highest similarity to subspecies novicida. Phylogenetic trees of full-length 16S rRNA gene, gyrA and recA sequences from species of the genera Wolbachia (class Alphaproteobacteria) and Francisella (class Gammaproteobacteria) indicated that W. persica ATCC VR-331T was most closely related to members of the genus Francisella and not Wolbachia. Local collinear blocks within the chromosome of strain ATCC VR-331T had considerable similarity with F. tularensis subsp. novicida, but not with any Wolbachia strain. The genomes of strain ATCC VR-331T and F. tularensis subsp. novicida Utah 112T ( = ATCC 15482T) contained an average nucleotide identity mean of 88.72 % and median of 89.18 %. Importantly, the genome of strain ATCC VR-331T contained one Francisella Pathogenicity Island, similar to F. tularensis subsp. novicida, as well as the Francisella-specific gene fopA1 and F. tularensis-specific genes fopA2 and lpnA (also referred to as tul4). In contrast to the obligate intracellular genus Wolbachia, strain ATCC VR-331T and facultative intracellular Francisella can replicate in specialized cell-free media. Collectively, these results demonstrate that Wolbachia persica should be reclassified in the genus Francisella as Francisella persica comb. nov. The type strain of Francisella persica comb. nov. is ATCC VR-331T ( = FSC845T = DSM 101678T). An emended description of the family Francisellaceae is also provided. PMID:26747442

  1. Stable optical frequency comb generation and applications in arbitrary waveform generation, signal processing and optical data mining

    NASA Astrophysics Data System (ADS)

    Ozharar, Sarper

    This thesis focuses on the generation and applications of stable optical frequency combs. Optical frequency combs are defined as equally spaced optical frequencies with a fixed phase relation among themselves. The conventional source of optical frequency combs is the optical spectrum of the modelocked lasers. In this work, we investigated alternative methods for optical comb generation, such as dual sine wave phase modulation, which is more practical and cost effective compared to modelocked lasers stabilized to a reference. Incorporating these comblines, we have generated tunable RF tones using the serrodyne technique. The tuning range was +/-1 MHz, limited by the electronic waveform generator, and the RF carrier frequency is limited by the bandwidth of the photodetector. Similarly, using parabolic phase modulation together with time division multiplexing, RF chirp extension has been realized. Another application of the optical frequency combs studied in this thesis is real time data mining in a bit stream. A novel optoelectronic logic gate has been developed for this application and used to detect an 8 bit long target pattern. Also another approach based on orthogonal Hadamard codes have been proposed and explained in detail. Also novel intracavity modulation schemes have been investigated and applied for various applications such as (a) improving rational harmonic modelocking for repetition rate multiplication and pulse to pulse amplitude equalization, (b) frequency skewed pulse generation for ranging and (c) intracavity active phase modulation in amplitude modulated modelocked lasers for supermode noise spur suppression and integrated jitter reduction. The thesis concludes with comments on the future work and next steps to improve some of the results presented in this work.

  2. Adolescents' questions about sex.

    PubMed

    Davis, S M; Harris, M B

    1983-12-01

    Male and female Anglo, Hispanic and Native American adolescents from urban and rural areas were given a chance to ask anonymous questions about sex. These questions were then used as the bases for subsequent presentations on sex education. The most popular categories of questions were reproduction, sexuality, and contraception, followed by anatomy, venereal disease, pregnancy, abortion, vocabulary, hygiene, and other diseases. Younger adolescents asked significantly more questions in most categories than older ones. Girls asked significantly more total questions and ones concerning pregnancy, contraception, and anatomy than boys. Students attending rural schools asked more questions about venereal disease than those in urban schools, but no other main effects of urban-rural location were found. There were no ethnic differences found. The adolescents' questions ranged from sophisticated to poignantly ignorant, suggesting that the strategy of adapting sex education sessions to fit the concerns of the specific adolescents involved might be valuable. PMID:6643199

  3. On the optimal sex ratio.

    PubMed Central

    Karlin, S; Lessard, S

    1983-01-01

    The equilibrium structures for various multiallele sex-determining genetic models of panmictic populations with sex expression depending on the genotypes of either the zygote or a parent are described. Even-sex-ratio equilibrium surfaces can exist apart from equilibrium points having coincident male and female allelic frequency sets. The latter (symmetric) equilibrium states entail biased sex ratios. A stable symmetric equilibrium and an even-sex-ratio equilibrium segregating the same alleles cannot coexist. The tendency to evolve toward an even-sex ratio is embodied by the following optimality property: starting from an equilibrium having a biased sex ratio, mutant sex-determining alleles can accumulate only in the case in which in the augmented system all attainable equilibrium states have a sex ratio closer to one to one. PMID:6577461

  4. Generation of Kerr combs centered at 4.5 μm in crystalline microresonators pumped with quantum-cascade lasers.

    PubMed

    Savchenkov, Anatoliy A; Ilchenko, Vladimir S; Di Teodoro, Fabio; Belden, Paul M; Lotshaw, William T; Matsko, Andrey B; Maleki, Lute

    2015-08-01

    We report on the generation of mid-infrared Kerr frequency combs in high-finesse CaF2 and MgF2 whispering-gallery-mode resonators pumped with continuous-wave room-temperature quantum cascade lasers. The combs were centered at 4.5 μm, the longest wavelength to date. A frequency comb wider than one half of an octave was demonstrated when approximately 20 mW of pump power was coupled to an MgF2 resonator characterized with quality factor exceeding 10(8). PMID:26258334

  5. Electronically reconfigurable bandpass microwave photonic filter using a windowed optical frequency comb

    NASA Astrophysics Data System (ADS)

    Deng, Hong; Fu, Songnian; Tang, Ming; Liu, Deming

    2015-03-01

    A center frequency-tunable multi-tap bandpass microwave photonic filter (MPF) is proposed and experimentally demonstrated, with reconfigurable capability by electronic control. A Mach-Zehnder modulator-based optical frequency comb (OFC) is used as an optical source, and its output is optically shaped before introducing a time delay by 70 km single-mode fiber (SMF) transmission. After an optical-to-electronic conversion, the frequency response in terms of central frequency and passband bandwidth can be electronically reconfigurable by varying either the input microwave frequency of the OFC or the waveshaper configuration without modification of the optical configuration. The experimental results show that more than a 35 dB out-of-band rejection ratio and at least a 3 GHz continuously tuning range of passband center frequency without any DC response can be successfully achieved.

  6. Multi-band local microwave signal generation based on an optical frequency comb generator

    NASA Astrophysics Data System (ADS)

    Wang, Wen Ting; Liu, Jian Guo; Sun, Wen Hui; Chen, Wei; Zhu, Ning Hua

    2015-03-01

    We propose and experimental demonstrate a new method to generate multi-band local microwave signals based on an optical frequency comb generator (OFCG) by applying an optical sideband injection locking technique and an optical heterodyning technique. The generated microwave signal can cover multi bands from S band to Ka band. A tunable multiband microwave signal spanning from 5 GHz to 40 GHz can be generated by the beating between the optical carrier and injection locked modulation sidebands in a photodetector without an optical filter. The wavelength of the slave laser can be continuously and near-linearly adjusted by proper changing its bias current. By tuning the bias current of the slave laser, the wavelength of that is matched to one of the modulation sidebands of the OFCG. The performance of the arrangement in terms of the tunability and stability of the generated microwave signal is also studied.

  7. Mid-infrared optical parametric oscillators and frequency combs for molecular spectroscopy.

    PubMed

    Vainio, M; Halonen, L

    2016-02-01

    Nonlinear optical frequency conversion is one of the most versatile methods to generate wavelength-tunable laser light in the mid-infrared region. This spectral region is particularly important for trace gas detection and other applications of molecular spectroscopy, because it accommodates the fundamental vibrational bands of several interesting molecules. In this article, we review the progress of the most significant nonlinear optics instruments for widely tunable, high-resolution mid-infrared spectroscopy: continuous-wave optical parametric oscillators and difference frequency generators. We extend our discussion to mid-infrared optical frequency combs, which are becoming increasingly important spectroscopic tools, owing to their capability of highly sensitive and selective parallel detection of several molecular species. To illustrate the potential and limitations of mid-infrared sources based on nonlinear optics, we also review typical uses of these instruments in both applied and fundamental spectroscopy. PMID:26804321

  8. Fibre optics wavemeters calibration using a self-referenced optical frequency comb

    SciTech Connect

    Galindo-Santos, J.; Velasco, A. V.; Corredera, P.

    2015-01-15

    Self-referenced optical frequency combs enable the measurement of optical frequencies with a very high accuracy, achieving uncertainties close to the atomic clock used as reference (<10{sup −13} s). In this paper, we present the technique for the measurement of laser frequencies for optical communications followed at IO-CSIC and its application to the calibration of two wavemeters in the 1.5 μm optical communication window. Calibration uncertainties down to 12 MHz and 59 MHz were obtained, respectively, for each of the devices. Furthermore, the long-term behaviour of the higher resolution wavemeter was studied during a 750 h period of sustained operation, exhibiting a dispersion in the measurements of 7.72 MHz. Temperature dependence of the device was analysed, enabling to further reduce dispersion down to a 2.15 MHz range, with no significant temporal deviations.

  9. Time-domain optical reflectometry measurements using a frequency comb interferometer.

    PubMed

    Taurand, Geneviève; Giaccari, Philippe; Deschênes, Jean-Daniel; Genest, Jérôme

    2010-08-10

    We characterize the temporal response of fiber-optic components using a fiber-based frequency comb interferometer; measurements are compared and validated against a commercial instrument. The main advantage of the instrument lies in the absence of moving parts or a tunable laser, leading to very fast scanning. A measurement of a mechanical distortion, cycled at 130 Hz, on a fiber Bragg grating (FBG) is presented. A complete profile of the mechanical distortion is taken every 2.5 ms (400 Hz scanning speed) and each "snapshot" is taken in 200 micros. This scanning speed was arbitrarily chosen, and the instrument could be set to scan much faster, up to hundreds of kilohertz. With high-reflectivity FBGs, the same instrument could scan simultaneously the profile of 140 wavelength-multiplexed FBGs at 2 kHz. PMID:20697444

  10. VizieR Online Data Catalog: A frequency Comb calibrated solar atlas (Molaro+, 2013)

    NASA Astrophysics Data System (ADS)

    Molaro, P.; Esposito, M.; Monai, S.; Lo Curto, G.; Gonzalez Hernandez, J. I.; Hansch, T. W.; Holzwarth, R.; Manescau, A.; Pasquini, L.; Probst, R. A.; Rebolo, R.; Steinmetz, T.; Udem, T.; Wilken, T.

    2013-10-01

    In November 2010 (an epoch of low solar activity), an experiment with a prototype of a Laser Frequency Comb (LFC) calibration system was performed with the HARPS spectrograph of the 3.6m ESO telescope at La Silla during which high signal-to-noise spectra of the Moon were obtained. We exploit those Echelle spectra to study a portion of the optical integrated solar spectrum and in particular to determine the solar photospheric line positions. The DAOSPEC program is used to measure solar line positions through gaussian fitting in an automatic way. The solar spectra are calibrated both with an LFC and a Th-Ar. The final atlas is corrected for all motions (Sun, Moon, Earth). (4 data files).

  11. Transmission characteristics of Mach-Zehnder interferometer comb filter based on thermal operation

    NASA Astrophysics Data System (ADS)

    Islam, M. S.; Mohammad, A. B.

    2014-10-01

    We propose and experimentally demonstrate switchable and tunable transmission characteristics of a Mach-Zehnder interferometer comb filter based on thermal operation. Its temperature characteristics are investigated to reveal a shift in the peak wavelength position from 0.003 to 0.004 nm/°C and a tunable range of wavelength spacing of 0.76-0.90 nm for maximum and minimum effective lengths, respectively. This configuration provides the unique advantages of an all-fiber structure, tunable wavelength spacing, switchable spectral peaks, independent tuning of the center wavelength and wavelength spacing of the spectral peaks, and low polarization sensitivity. It is relatively simple to fabricate and expected to have applications in temperature fiber optic sensors and multiwavelength fiber laser sources.

  12. Fibre optics wavemeters calibration using a self-referenced optical frequency comb.

    PubMed

    Galindo-Santos, J; Velasco, A V; Corredera, P

    2015-01-01

    Self-referenced optical frequency combs enable the measurement of optical frequencies with a very high accuracy, achieving uncertainties close to the atomic clock used as reference (<10(-13) s). In this paper, we present the technique for the measurement of laser frequencies for optical communications followed at IO-CSIC and its application to the calibration of two wavemeters in the 1.5 ?m optical communication window. Calibration uncertainties down to 12 MHz and 59 MHz were obtained, respectively, for each of the devices. Furthermore, the long-term behaviour of the higher resolution wavemeter was studied during a 750 h period of sustained operation, exhibiting a dispersion in the measurements of 7.72 MHz. Temperature dependence of the device was analysed, enabling to further reduce dispersion down to a 2.15 MHz range, with no significant temporal deviations. PMID:25638069

  13. Coarse-Frequency-Comb Multiple-Beam Interferometry: Phase Assessment Using Common Phase Shifting Procedures

    NASA Astrophysics Data System (ADS)

    Schwider, J.

    2010-04-01

    Real wedge interferometers of the Fizeau-type do not allow for fringes in case of a spectral broad band source -or in short: for white light fringes. Here, the use of a suitable frequency comb source will help to overcome this limitation on the one hand and on the other it offers the capability for enhanced phase sensitivity in high precision measurements of surface deviations. Frequency combs can be produced by passive filtering of the light emitted by a broad band source as a superlum-diode or a fs-laser. The frequency comb produced by a common fs-laser is extremely fine, i.e., the frequency difference of consecutive peaks is very small or the distance of consecutive pulses of the pulse train might be of the order of 1 m. Therefore, the coarse pulse train produced by passive filtering of a broad band source is better adapted to the needs of surface testing interferometers. White light fringes are either applied for the profiling of discontinuous surfaces or can serve as an indication for the correct choice of the subdivision of the inter order distance for multiple beam fringes. During the last decennium it became more and more clear that spatially incoherent sources provide better measuring accuracy in surface measurements due to the reduced influence of dust diffraction patterns. The advantage of laser illumination can nevertheless be maintained if the laser light is made spatially incoherent through moving scatterers in the light path. Here, we will discuss the application of spatially incoherent broad band light frequency filtered through a Fabry-Perot filter. The main applications are in the following fields: (1) surface profiling applications using two-beam Fizeau interferometers, (2) selection of single cavities out of a series of interlaced cavities, and (3) sensitivity enhancement for multi-beam interferometers for planeness or sphericity measurements. The emphasis of the presented work will be on the sensitivity enhancement provided by multiple beam interferometry in combination with frequency comb illumination. Through the use of a set of properly selected wavelengths the resulting interference pattern will become on the one hand more and more cosine-type with increasing enhancement factors and on the other hand it will be shown how the nonlinear relationship of the intensity distribution on the phase in the multiple beam interferometer can be overcome. Typical systematic errors show a periodicity with 4-times the fringe frequency of the interference pattern. By using the averaging of the measuring results of two measurements having a phase offset of π/4 it is possible to reduce this error by at least one order of magnitude. The impact of the nonlinear intensity profile of multiple beam fringes in transmitted light can in addition be reduced through inverted intensity values in the common phase shifting equations. It will be shown that in this way repeatability values can be obtained of 1.2 A˚ peak to valley and 0.12 A˚ rms.

  14. Reclassification of Saccharomycodes sinensis, Proposal of Yueomyces sinensis gen. nov., comb. nov. within Saccharomycetaceae (Saccharomycetales, Saccharomycotina)

    PubMed Central

    Wang, Long; Groenewald, Marizeth; Wang, Qi-Ming; Boekhout, Teun

    2015-01-01

    The phylogenetic position of Saccharomycodes sinensis has been debated by yeast taxonomists. In this study, a multigene phylogenetic analysis based on four regions, namely the 18S ribosomal DNA (rDNA), the D1/D2 domains of the 26S rDNA, the second largest subunit of RNA polymerase II gene (RPB2) and translation elongation factor 1-α gene (EF1-α), were performed to address the phylogenetic placement of S. sinensis. Our result indicated that S. sinensis belongs to Saccharomycetaceae instead of Saccharomycodaceae, and forms a single species lineage divergent from the other genera within Saccharomycetaceae. Yueomyces gen. nov. (MycoBank No. MB 811648) is proposed in the Saccharomycetaceae with Y. sinensis comb. nov. (MycoBank No. MB 811649, type strain CGMCC 2.01395T = IFO 10111T = CBS 7075T) as the type species. PMID:26375944

  15. Spin frequency comb echo memory controlled by a pulsed-gradient of magnetic field

    NASA Astrophysics Data System (ADS)

    Gerasimov, K. I.; Moiseev, S. A.; Morozov, V. I.; Zaripov, R. B.

    2015-03-01

    The controllable storage and on demand retrieval of the microwave pulses by using the photon echo quantum memory approach based on a spin frequency comb of inhomogeneous broadening (SFC- protocol) have been demonstrated. We have used an electron-nuclear spin ensemble of tetracyanoethylene anion radicals in toluene which has a natural periodic structure of narrow electron-spin resonance (ESR) hyperfine lines. On-demand retrieval of the stored field has been realized by using two pulses of the magnetic field gradient of an opposite polarity which hold the electron spins in a dephased excited state during the storage time. The obtained experimental results demonstrate promising properties for coherent controlling the electron-nuclear spin ensemble of radicals in liquid that could be useful for implementation of room-temperature broadband quantum memory.

  16. Differential Stark shift measurement of clock states of Yb+ using an optical frequency comb

    NASA Astrophysics Data System (ADS)

    Quraishi*, Qudsia; Hayes, David; Hucul, David; Matsukevich, Dzmitry; Debnath, Shantanu; Clark, Susan; Monroe, Chris

    2011-03-01

    Quantum information processing with trapped ions has traditionally involved state preparation, manipulation (eg. quantum gates) and detection using CW lasers. Quantum gates implemented with ions typically involve optical Raman transitions between two atomic levels. An optical frequency comb, emitted by a pulsed laser, is an excellent tool for bridging atomic frequency differences. Previously, we demonstrated quantum gates and separately, ultrafast spin manipulation, using pulsed lasers [1,2]. Unlike the CW case, employing pulsed lasers has the marked advantage of both low spontaneous emission and low AC Stark shifts, because the high powers available from pulsed lasers allow for larger detunings from optical resonance. Here, we show both experimentally and theoretically the scaling of the differential Stark shift with detuning (6 THz to 20 THz) of the Raman fields, achieving values of 10-3 of the Rabi frequency.

  17. Bottlebrush and comb-like elastomers as ultra-soft electrical and acoustically active materials

    NASA Astrophysics Data System (ADS)

    Daniel, William; Vatankhah-Varnosfaderani, Mohammad; Pandya, Ashish; Burdynska, Joanna; Morgan, Benjamin; Everhart, Matthew; Matyjaszewski, Krzysztof; Dobrynin, Andrey; Rubinstein, Michael; Sheiko, Sergei; UNC MIRT Team

    Without swelling in a solvent, it is challenging to obtain materials with a modulus below 105 Pa, which is dictated by chain entanglements. We show that macromolecules can be disentangled by dense grafting of side chains to long polymer chains. The bottlebrush and comb-like architectures demonstrate a unique combination of flexibility and network dilution, leading to significant decrease of the entanglement modulus (Ge) and increase of extensibility. Following theoretical predictions, it has been shown that the Ge is controlled by the polymerization degrees of sidechains (nsc) and grafting spacer (ng) as Ge ~ (ng /nsc) 1 . 5 . Using the reduced entanglement density, we developed solvent-free elastomers with moduli on the order of 100 Pa and excellent extensibility. Using bottlebrush architectures we have developed PDMS dielectric actuators with high deformation at low electric field strength. Additionally strong acoustic adsorption leads to materials showing shape and volume control in light opaque environments. NSF (DMR 1409710, DMR 1122483, DMR 1407645, and DMR 1436201).

  18. Monolithic CEO-stabilization scheme-based frequency comb from an octave-spanning laser

    NASA Astrophysics Data System (ADS)

    Zi-Jiao, Yu; Hai-Nian, Han; Yang, Xie; Hao, Teng; Zhao-Hua, Wang; Zhi-Yi, Wei

    2016-04-01

    We demonstrate a carrier-envelope phase-stabilized octave-spanning oscillator based on the monolithic scheme. A wide output spectrum extending from 480 nm to 1050 nm was generated directly from an all-chirped mirror Ti:sapphire laser. After several improvements, the carrier-envelope offset (CEO) beat frequency accessed nearly 60 dB under a resolution of 100 kHz. Using a feedback system with 50-kHz bandwidth, we compressed the residual phase noise to 55 mrad (integrated from 1 Hz to 1 MHz) for the stabilized CEO, corresponding to 23-as timing jitter at the central wavelength of 790 nm. This is, to the best of our knowledge, the smallest timing jitter achieved among the existing octave-spanning laser based frequency combs. Project supported by the National Basic Research Program of China (Grant No. 2012CB821304) and the National Natural Science Foundation of China (Grant Nos. 11078022 and 61378040).

  19. Properties of ultrasonic acoustic resonances for exploitation in comb construction by social hornets and honeybees

    NASA Astrophysics Data System (ADS)

    Kadmon, Jonathan; Ishay, Jacob S.; Bergman, David J.

    2009-06-01

    Physical and mathematical considerations are presented in support of the suggestion that social hornets and bees, which construct brood combs with large arrays of cells in a honeycomb structure, exploit ultrasonic acoustic resonances in those cells in order to achieve the great accuracy of the hexagonal symmetry exhibited by these honeycomb-structured arrays. We present a numerical calculation of those resonances for the case of a perfect-hexagon duct utilizing a Bloch-Floquet-type theorem. We calculate the rate of energy dissipation in those resonances and use that, along with other considerations, to identify the resonance that is best suited for the suggested use by bees and hornets. Previously recorded ultrasonic data on social hornets and honeybees are cited which agree with some of our predictions and thus provide support for the above-mentioned suggestion.

  20. Coherent storage of temporally multimode light using a spin-wave atomic frequency comb memory

    NASA Astrophysics Data System (ADS)

    Gündoǧan, M.; Mazzera, M.; Ledingham, P. M.; Cristiani, M.; de Riedmatten, H.

    2013-04-01

    We report on the coherent and multi-temporal mode storage of light using the full atomic frequency comb memory scheme. The scheme involves the transfer of optical atomic excitations in Pr3+:Y2SiO5 to spin waves in hyperfine levels using strong single-frequency transfer pulses. Using this scheme, a total of five temporal modes are stored and recalled on-demand from the memory. The coherence of the storage and retrieval is characterized using a time-bin interference measurement resulting in visibilities higher than 80%, independent of the storage time. This coherent and multimode spin-wave memory is promising as a quantum memory for light.

  1. Absolute distance measurement by dual-comb nonlinear asynchronous optical sampling.

    PubMed

    Zhang, Hongyuan; Wei, Haoyun; Wu, Xuejian; Yang, Honglei; Li, Yan

    2014-03-24

    A dual-comb nonlinear asynchronous optical sampling method is proposed to simplify determination of the time interval and extend the non-ambiguity range in absolute length measurements. Type II second harmonic generation facilitates curve fitting in determining the time interval between adjacent pulses. Meanwhile, the non-ambiguity range is extended by adjusting the repetition rate of the signal laser. The performance of the proposed method is compared with a heterodyne interferometer. Results show that the system achieves a maximum residual of 100.6 nm and an uncertainty of 1.48 ?m in a 0.5 ms acquisition time. With longer acquisition time, the uncertainty can be reduced to 166.6 nm for 50 ms and 82.9 nm for 500 ms. Moreover, the extension of the non-ambiguity range is demonstrated by measuring an absolute distance beyond the inherent range determined by the fixed repetition rate. PMID:24664008

  2. Precise measurements of optical cavity dispersion and mirror coating properties via femtosecond combs.

    PubMed

    Thorpe, Micheal; Jones, R; Moll, K; Ye, Jun; Lalezari, Ramin

    2005-02-01

    We precisely determine the dispersion of an optical cavity over a large spectral bandwidth using a broadband optical comb generated by a femtosecond laser. This approach permits the effective characterization of the next generation of mirrors that will offer high reflectivity, minimal absorption/scattering loss, and well-defined dispersion characteristics. Such mirrors are essential for constructing passive, high-finesse cavities capable of storing and enhancing ultrashort pulses and for exploring novel intracavity-based experiments in atomic and molecular spectroscopy and extreme nonlinear optics. We characterize both zero and negative group-delay-dispersion mirrors and compare their performance against the targeted coating design. The high sensitivity of this approach is demonstrated with a precise determination of the group-delay dispersion of air inside a 40-cm long optical cavity, demonstrating an accuracy better than 1 fs2. PMID:19494950

  3. Semi-permeable coatings fabricated from comb-polymers efficiently protect proteins in vivo

    NASA Astrophysics Data System (ADS)

    Liu, Mi; Johansen, Pål; Zabel, Franziska; Leroux, Jean-Christophe; Gauthier, Marc A.

    2014-11-01

    In comparison to neutral linear polymers, functional and architecturally complex (that is, non-linear) polymers offer distinct opportunities for enhancing the properties and performance of therapeutic proteins. However, understanding how to harness these parameters is challenging, and studies that capitalize on them in vivo are scarce. Here we present an in vivo demonstration that modification of a protein with a polymer of appropriate architecture can impart low immunogenicity, with a commensurably low loss of therapeutic activity. These combined properties are inaccessible by conventional strategies using linear polymers. For the model protein L-asparaginase, a comb-polymer bio-conjugate significantly outperformed the linear polymer control in terms of lower immune response and more sustained bioactivity. The semi-permeability characteristics of the coatings are consistent with the phase diagram of the polymer, which will facilitate the application of this strategy to other proteins and with other therapeutic models.

  4. Sex in Geneva, sex in Lilongwe, and sex in Balaka.

    PubMed

    Tawfik, Linda; Watkins, Susan Cotts

    2007-03-01

    This paper compares three interpretations of women and the transmission of HIV in rural Malawi. One is disseminated world-wide by institutions with a global reach such as the World Health Organization in Geneva and United States Agency for International Development (USAID); the second is provided by urban Malawians situated in the capital of Lilongwe, the seat of government and the site of the many international and national non-governmental agencies; the third is articulated by rural women and men in Balaka District, Malawi. We focus on women's motivations for extramarital sex, using qualitative interview data. We find that whereas in Geneva and Lilongwe women from rural Malawi are said to engage in sexual relationships outside of marriage because they need money for survival, in Balaka they are said to be motivated not only by money for survival but also for attractive consumer goods as well as by passion and by revenge for a husband's infidelity. We also find that data collection procedures influence explanations for women's affairs, as does the respondent's gender. An implication of this study is that AIDS-prevention policies based on the view from Geneva and Lilongwe need modification for Balaka, and by implication for rural Africa more generally. PMID:17123678

  5. Oil industry wastewater treatment with fouling resistant membranes containing amphiphilic comb copolymers.

    PubMed

    Asatekin, Ayse; Mayes, Anne M

    2009-06-15

    The oil industry produces large volumes of wastewater, including oil well produced water brought to the surface during oil drilling, and refinery wastewater. These streams are difficult to treat due to large concentrations of oil. Ultrafiltration (UF) is very promising for their treatment to remove oil, but has been limited by economic obstacles due to severe membrane fouling. In a recent study, novel UF membranes incorporating the amphiphilic comb copolymer additive polyacrylonitrile-graft-poly(ethylene oxide), PAN-g-PEO, were found to exhibit complete resistance to irreversible fouling by several classes of organic foulants (J. Membr. Sci. 2007, 298, 136-146). The current work focuses on application of these novel UF membranes to the treatment of oily wastewater feed streams, employing three industrial samples of oil well produced water and refinery wastewater. UF membranes cast with 20 wt % PAN-g-PEO in PAN achieved removals of dispersed and free oils of over 96% based on chemical oxygen demand (COD) for produced water samples, comparable to a PAN UF commercial membrane control. For refinery wastewater treatment the COD removal values were substantially lower, between 41 and 44%, due to higher contents of dissolved organics. Comb copolymer modified membranes showed significantly better fouling resistance than controls, recovering fully their initial fluxes after a simulated backwash for each of the three wastewater samples tested. The results indicate that UF membranes incorporating PAN-g-PEO can be cleaned completely by physical methods alone, which should extend membrane lifetimes substantially and improve the process economics for treatment of oil-contaminated waters. PMID:19603666

  6. Parallel-kinematic-mechanism-based monolithic XY micropositioning stage with rotary comb drive actuators

    NASA Astrophysics Data System (ADS)

    Mukhopadhyay, Deepkishore; Dong, Jingyan; Ferreira, Placidus M.

    2008-02-01

    Micro-positioning stages fabricated using Micro Electro Mechanical Systems (MEMS) based processes have been critical in enabling micro/nano manipulation and probing. These stages have been extensively used in micro-force sensors, scanning probe microscopy and micro optical lens scanners. This paper presents the design, kinematic and dynamic analysis, fabrication and characterization of a novel monolithic micro-positioning XY stage. The design of the proposed micro-positioning stage is based on a Parallel Kinematic Mechanism (PKM). The PKM based design decouples the motion in the XY direction. Additionally, it restricts the parasitic rotation of the end-effector (table) of the micro-positioning stage while providing an increased motion range. The motion of the stage is linear in the operating range thus simplifying its kinematics. The truss like parallel kinematic mechanism design of the stage structure reduces its mass while keeping the stage stiffness high. This leads to a high natural frequency of the micro-positioning stage (1250Hz) and a high Q-factor of 156. The stage mechanism is fabricated on a Silicon-On-Insulator (SOI) substrate and is actuated by integrated electrostatic rotary comb drives. The fabrication process uses multi-layer patterning along with an Inductively Coupled Plasma Deep Reactive Ion Etching (ICP-DRIE). The use of ICP-DRIE enables the high aspect ratio etching that is required for the stage fabrication and its optimal actuation using the integrated electrostatic rotary comb drives. The fabricated stages have a motion range of more than 30 microns of decoupled displacements along the X and Y directions at a driving voltage of 200V.

  7. High Resolution Spectroscopy of Naphthalene Calibrated by AN Optical Frequency Comb

    NASA Astrophysics Data System (ADS)

    Nishiyama, Akiko; Nakashima, Kazuki; Matsuba, Ayumi; Misono, Masatoshi

    2015-06-01

    In high-resolution molecular spectroscopy, the precise measure of the optical frequency is crucial to evaluate minute shifts and splittings of the energy levels. On the other hand, in such spectroscopy, thousands of spectral lines distributed over several wavenumbers have to be measured by a continuously scanning cw laser. Therefore, the continuously changing optical frequency of the scanning laser has to be determined with enough precision. To satisfy these contradictory requirements, we have been developed two types of high-resolution spectroscopic systems employing an optical frequency comb. One of the systems employs RF band-pass filters to generate equally spaced frequency markers for optical frequency calibration, and is appropriate for wide wavelength-range measurement with relatively high scanning rate.^a In the other system, the beat frequency between the optical frequency comb and the scanning laser is controlled by an acousto-optic frequency shifter. This system is suitable for more precise measurement, and enables detailed analyses of frequency characteristics of scanning laser.^b In the present study, we observe Doppler-free two-photon absorption spectra of A^1B1u (v_4 = 1) ← X^1A_g (v = 0) transition of naphthalene around 298 nm. The spectral lines are rotationally resolved and the resolution is about 100 kHz. For ^qQ transition, the rotational lines are assigned, and molecular constants in the excited state are determined. In addition, we analyze the origin of the measured linewidth and Coriolis interactions between energy levels. To determine molecular constants more precisely, we proceed to measure and analyze spectra of other transitions, such as ^sS transitions. ^a A. Nishiyama, D. Ishikawa, and M. Misono, J. Opt. Soc. Am. B 30, 2107 (2013). ^b A. Nishiyama, A. Matsuba, and M. Misono, Opt. Lett. 39, 4923 (2014).

  8. Combinations of Earth Orientation Measurements: SPACE94, COMB94, and POLE94

    NASA Technical Reports Server (NTRS)

    Gross, Richard S.

    1996-01-01

    A Kalman filter has been used to combine independent measurements of the Earth's orientation taken by the space-geodetic observing techniques of lunar laser ranging, satellite laser ranging, very long baseline interferometry, and the Global Positioning System. Prior to their combination, the data series were adjusted to have the same bias and rate, the stated uncertainties of the measurements were adjusted, and data points considered to be outliers were deleted. The resulting combination, SPACE94, consists of smoothed, interpolated polar motion and UT1-UTC values spanning October 6, 1976, to January 27, 1995, at 1-day intervals. The Kalman filter was then used to combine the space-geodetic series comprising SPACE94 with two different, independent series of Earth orientation measurements taken by the technique of optical astrometry. Prior to their combination with SPACE94, the bias, rate and annual term of the optical astrometric series were corrected, the stated uncertainties of the measurements were adjusted, and data points considered to be outliers were deleted. The adjusted optical astrometric series were then combined with SPACE94 in two steps: (1) the Bureau International de l'Heure (BIH) optical astrometric series was combined with SPACE94 to form COMB94, a combined series of smoothed, interpolated polar motion and UT1-UTC values spanning January 20, 1962, to January 27, 1995, at 5-day intervals, and (2) the International Latitude Service (ILS) optical astrometric series was combined with COMB94 to form POLE94, a combined series of smoothed, interpolated polar motion values spanning January 20, 1900, to January 21, 1995, at 30.4375-day intervals.

  9. Charge optimized many-body (COMB) potential for dynamical simulation of Ni–Al phases

    NASA Astrophysics Data System (ADS)

    Kumar, Aakash; Chernatynskiy, Aleksandr; Liang, Tao; Choudhary, Kamal; Noordhoek, Mark J.; Cheng, Yu-Ting; Phillpot, Simon R.; Sinnott, Susan B.

    2015-08-01

    An interatomic potential for the Ni–Al system is presented within the third-generation charge optimized many-body (COMB3) formalism. The potential has been optimized for Ni3Al, or the γ‧ phase in Ni-based superalloys. The formation energies predicted for other Ni–Al phases are in reasonable agreement with first-principles results. The potential further predicts good mechanical properties for Ni3Al, which includes the values of the complex stacking fault (CSF) and the anti-phase boundary (APB) energies for the (1 1 1) and (1 0 0) planes. It is also used to investigate dislocation propagation across the Ni3Al (1 1 0)–Ni (1 1 0) interface, and the results are consistent with simulation results reported in the literature. The potential is further used in combination with a recent COMB3 potential for Al2O3 to investigate the Ni3Al (1 1 1)–Al2O3 (0 0 01) interface, which has not been modeled previously at the classical atomistic level due to the lack of a reactive potential to describe both Ni3Al and Al2O3 as well as interactions between them. The calculated work of adhesion for this interface is predicted to be 1.85 J m‑2, which is in agreement with available experimental data. The predicted interlayer distance is further consistent with the available first-principles results for Ni (1 1 1)–Al2O3 (0 0 0 1).

  10. Sex and Cognition.

    ERIC Educational Resources Information Center

    Kimura, Doreen

    This book describes the major differences between men and women in cognitive or problem-solving abilities and discusses the possible biological contributions to such differences. The book argues that sex differences in cognitive patterns and in motor skills arose out of complementary evolutionary histories of men and women and that evidence for…

  11. Adolescents and sex.

    PubMed

    Castro, C; Palomar Castro, Y

    1992-01-01

    Adolescent health problems in the Philippines are identified as follows: adolescent unwanted pregnancy, early marriage, abortion and sometimes death, sexually transmitted disease (STD), AIDS, inadequate knowledge about sex and reproduction (population education), taboos, inadequate resources directed to youth, and personnel insufficiently trained for gender sensitive and adolescent sensitive counseling. A recent University of the Philippines Population Institute survey reported that only 10% of urban respondents and 8.1% of rural respondents considered virginity to be unimportant. 33% in urban and 29% in rural areas consent to premarital sex if the couple were "in love" and there was a promise of marriage. Premarital sex is increasing, but was lower among those who grew up with their parents. Population education is compulsory but teachers are ill equipped, unknowledgeable about the latest technology, and biased. Human reproduction is taught but family planning methods are frequently ignored. The topic is taboo between parents and children. Acquisition of knowledge is haphazard at best. Government resources are directed to adult reproductive women. Emphasis needs to be placed on the importance and proper use of pills, condoms, IUDs, and diaphragms. Vasectomy and tubal ligation should be readily available. Youth should be taught rhythm, basal body temperature, and Billings ovulation methods. Misconceptions should be debunked. Sex education, STD prevention, and counseling for adolescents are available in only 5 centers in the Philippines, as reported by the International Center on Adolescent Fertility; this is adequate to serve the almost 50% of the population 18 years. PMID:12285922

  12. Sex Education and Ideals

    ERIC Educational Resources Information Center

    de Ruyter, Doret J.; Spiecker, Ben

    2008-01-01

    This article argues that sex education should include sexual ideals. Sexual ideals are divided into sexual ideals in the strict sense and sexual ideals in the broad sense. It is argued that ideals that refer to the context that is deemed to be most ideal for the gratification of sexual ideals in the strict sense are rightfully called sexual…

  13. Sex-Role Psychology.

    ERIC Educational Resources Information Center

    Wesley, Frank; Wesley, Claire

    The book explores the psychological aspects of sex-role development and investigates various approaches which have been suggested to provide greater equality between females and males. Chapter one describes the psychology of women and identifies possible approaches toward integration of male and female characteristics. Chapter two discusses

  14. Sex, Technology and Morality.

    ERIC Educational Resources Information Center

    Case, Verna; And Others

    1986-01-01

    Provides an overview of the course "Sex, Technology, and Morality" which focuses on the human reproductive process and examines the advances in reproductive technology. The course emphasizes the social, political, and ethical implications of actual and possible technologies associated with human reproduction. (ML)

  15. Sex Therapy and Mastectomy

    ERIC Educational Resources Information Center

    Witkin, Mildred Hope

    1975-01-01

    Because the emotional trauma associated with a mastectomy exceeds the physical trauma, the recovery of the woman is greatly affected by the response of her husband or lover. Sex therapy, therefore, involves the couple. The approach described is aimed at assisting the couple to confront and integrate the mastectomy experience. (Author)

  16. Television's New Sex Education

    ERIC Educational Resources Information Center

    Levinsohn, Florence Hamlish

    1977-01-01

    Author is concerned with sexual identity as it may be being learned by youngsters (including her youngster) from their TV screens. She is concerned that young people are viewing as natural and normal the presentation of sex on television as a routine, affectless experience in which women are the objects of men's lust. (Editor/RK)

  17. How Sex Attitudes Develop

    ERIC Educational Resources Information Center

    Arnstein, Helene S.

    1976-01-01

    Excerpt from "The Roots of Love" (Helene S. Arnstein, 1975). Book is concerned with feelings that are part of child's developmental stages. Included in excerpt are: genital self-discovery, masturbation, discovery of sex differences, and birth fantasies. Stresses importance of parent's feelings which are communicated to child.

  18. Sex, Courtship, and Marriage.

    ERIC Educational Resources Information Center

    Seiferth, Berniece

    The author presents an historical perspective on abortion, contraception and marriage as a prelude to an examination of changing attitudes toward sex. The article deals with the negative effects attributed to the increased incidence of early dating and early marriage of teenagers in the United States. The author also assumes positions on such…

  19. Let's talk about sex.

    PubMed

    Warriner, Jason; Power, Lisa

    In a bid to ensure UK adults know the facts when it comes to sexual health, the Department of Health and the Department for Children, Schools and Families, together with the National Chlamydia Screening Programme have launched the 'Sex. Worth Talking About' campaign. Jason Warriner and Lisa Power explore the crucial role that nurses can play in educating and empowering young adults. PMID:20081688

  20. Sex-Role Psychology.

    ERIC Educational Resources Information Center

    Wesley, Frank; Wesley, Claire

    The book explores the psychological aspects of sex-role development and investigates various approaches which have been suggested to provide greater equality between females and males. Chapter one describes the psychology of women and identifies possible approaches toward integration of male and female characteristics. Chapter two discusses…

  1. Sex And People.

    ERIC Educational Resources Information Center

    Jones, Kenneth L.; And Others

    This textbook for the college student emphasizes human sexuality as a part of the whole human life experience and contains a balance of biological, psychological, and sociological material. In 16 chapters the following topics are covered: (1) sex and society; (2) historical and cultural perspectives; (3) glandular control of sexual physiology; (4)

  2. Sex And People.

    ERIC Educational Resources Information Center

    Jones, Kenneth L.; And Others

    This textbook for the college student emphasizes human sexuality as a part of the whole human life experience and contains a balance of biological, psychological, and sociological material. In 16 chapters the following topics are covered: (1) sex and society; (2) historical and cultural perspectives; (3) glandular control of sexual physiology; (4)…

  3. Sex, Sex-Role Identification, and the Good Manager.

    ERIC Educational Resources Information Center

    Powell, Gary N.; Butterfield, D. Anthony

    The purpose of the present study was to determine the influences of sex and sex-role identification on the perceived characteristics of a good manager. A sample of 335 students from various undergraduate and graduate business courses completed the Bem Sex-Role Inventory both for themselves and for a good manager. Three hypotheses were tested--that…

  4. Disestablishing Sex: The Case for Released-Time Sex Education

    ERIC Educational Resources Information Center

    Glanzer, Perry L.

    2011-01-01

    Allowing nonschool organizations to provide sex education in a released-time format would disestablish state-funded sex education and give families a choice in the sex education that would be provided for their children. Released-time programs, as originally conceived and currently practiced, allow students to be released for a period of time…

  5. Disestablishing Sex: The Case for Released-Time Sex Education

    ERIC Educational Resources Information Center

    Glanzer, Perry L.

    2011-01-01

    Allowing nonschool organizations to provide sex education in a released-time format would disestablish state-funded sex education and give families a choice in the sex education that would be provided for their children. Released-time programs, as originally conceived and currently practiced, allow students to be released for a period of time

  6. Sex Role Attitudes and Sex Role Stereotyping: Recent Literature.

    ERIC Educational Resources Information Center

    New Jersey Research Bulletin, 1996

    1996-01-01

    This annotated bibliography profiles 17 publications examining sex role attitudes/sex role stereotyping from the perspectives of ethnicity, gender, and age. Cited in the section on ethnicity are studies of work satisfaction/family functioning among working-class Mexican-American women and cultural variations in sex typing by students in the United…

  7. Sex and stripping

    PubMed Central

    Pellecchia, Marco; Grève, Pierre; Daffonchio, Daniele; Bandi, Claudio; Alma, Alberto

    2010-01-01

    Wolbachia pipientis is known to infect only arthropods and nematodes (mainly filarial worms). A unique feature shared by the two Phyla is the ability to replace the exoskeleton, a process known as ecdysis. This shared characteristic is thought to reflect a common ancestry. Arthropod moulting is induced by the steroid hormone 20-hydroxyecdysone (20E) and a role for ecdysteroids in nematode ecdysis has also been suggested. Removing Wolbachia from filarial worms impairs the host’s development. From analyses of the genome of Wolbachia harbored by the filarial nematode Brugia malayi and that of its host, the bacterium may provide a source of heme, an essential component of cytochrome P450’s that are necessary for steroid hormone biosynthetic pathways. In arthropods, Wolbachia is a reproductive manipulator, inducing various phenotypic effects that may be due to differences in host physiology, in particular, endocrine-related processes governing development and reproduction. Insect steroids have well-defined roles in the coordination of multiple developmental processes, and in adults they control important aspects of reproduction, including ovarian development, oogenesis, sexual behavior, and in some taxa vitellogenin biosynthesis. According to some authors ecdysteroids may also act as sex hormones. In insects sex differentiation is generally thought to be a strictly genetic process, in which each cell decides its own sexual fate based on its sex chromosome constitution, but, surprisingly, recent data demonstrate that in Drosophila sex determination is not cell-autonomous, as it happens in mammals. Thus the presence of signals coordinating the development of a gender-specific phenotype cannot be excluded. This could explain why Wolbachia interferes with insect reproduction; and also could explain why Wolbachia interferes with insect development. Thus, is “sex (=reproduction) and stripping (=ecdysis)” the key to the intimate relationship between Wolbachia and its host? PMID:20585501

  8. Sex education in France.

    PubMed

    Gallard, C

    1991-05-01

    The French Family Planning Movement (MFPF) has actively been involved in sex education within schools. In 1989, more than 1500 presentations were made to 23,000 pupils. Another activity is monitoring the application of statutes and regulations, for abortion, contraception, and sex education, and fighting to save and advance the rights of sexuality experts. Because of MFPF prominence in serious risks such as AIDs, sexual abuse, and rape, credibility has been enhanced. MFPF serves as a vehicle to change attitudes on male/female relationships. The government has permitted involvement in the preparation of a teaching program dealing with sexual abuse. The dominant influence of the Catholic Church on education has been evident since 1807. Up to WWI, religious morality was dominant. With Freud's contributions to the importance of sexuality in individual life, there were questions raised and a call for change in values and customs. In 1967, the statute was passed which authorized contraception, and sex education became an important issue. In 1973, Fontanet as Minister of Education outlined the recommendation for sex information and education in schools, including reproduction. Further official supportive recommendations were not made until 1985 when life education was entered into the primary syllabus. There was no provision even for teacher training; hence a wide variability in skills, commitment, and attitudes prevailed. MFPF reflects a position on tolerance in listening to others, expression and analysis of differences and critical thinking, identifying difficulties in talking about sex with respect to cultural and religious diversity, and help for the young in learning about their bodies, expressing feelings, and taking charge of emotions. PMID:12343168

  9. The ABCs of Sex Ed.

    ERIC Educational Resources Information Center

    Sroka, Stephen R.

    2002-01-01

    Cites statistics on extent of sexually transmitted diseases and pregnancies among adolescents; describes ideological dispute over how to teach sex education; advocates teaching the ABCs of sex education: Abstinence, Be Monogamous, and Condoms. (PKP)

  10. Abnormal human sex chromosome constitutions

    SciTech Connect

    1993-12-31

    Chapter 22, discusses abnormal human sex chromosome constitution. Aneuploidy of X chromosomes with a female phenotype, sex chromosome aneuploidy with a male phenotype, and various abnormalities in X chromosome behavior are described. 31 refs., 2 figs.

  11. Hypnotic Psychotherapy with Sex Offenders

    ERIC Educational Resources Information Center

    Moseley, Sullivan; Briggs, Wanda P.; Magnus, Virginia

    2005-01-01

    The authors review the literature on the prevalence of sex offenders; multiple treatment modalities; and implications of the use of hypnotic psychotherapy, coupled with cognitive behavioral treatment programs, for treating sex offenders. (Contains 2 tables.)

  12. Same-Sex Relationship Violence

    MedlinePlus

    ... of violence against women Violence Against Women Same-sex relationship violence Click the red escape button above ... punishments. Return to top More information on Same-sex relationship violence Explore other publications and websites Dating ...

  13. SHBG (Sex Hormone Binding Globulin)

    MedlinePlus

    ... as: Testosterone-estrogen Binding Globulin; TeBG Formal name: Sex Hormone Binding Globulin Related tests: Testosterone , Free Testosterone, ... I should know? How is it used? The sex hormone binding globulin (SHBG) test may be used ...

  14. Dyspareunia: Painful Sex for Women

    MedlinePlus

    ... part of the genitals can cause pain during sex. Some conditions affect the skin around the vagina. ... types of birth control) does not fit correctly, sex may also be painful. Vaginismus (say: "vag-in- ...

  15. Sex Differences and Sex Steroids in Lung Health and Disease

    PubMed Central

    Townsend, Elizabeth A.; Miller, Virginia M.

    2012-01-01

    Sex differences in the biology of different organ systems and the influence of sex hormones in modulating health and disease are increasingly relevant in clinical and research areas. Although work has focused on sex differences and sex hormones in cardiovascular, musculoskeletal, and neuronal systems, there is now increasing clinical evidence for sex differences in incidence, morbidity, and mortality of lung diseases including allergic diseases (such as asthma), chronic obstructive pulmonary disease, pulmonary fibrosis, lung cancer, as well as pulmonary hypertension. Whether such differences are inherent and/or whether sex steroids play a role in modulating these differences is currently under investigation. The purpose of this review is to define sex differences in lung structure/function under normal and specific disease states, with exploration of whether and how sex hormone signaling mechanisms may explain these clinical observations. Focusing on adult age groups, the review addresses the following: 1) inherent sex differences in lung anatomy and physiology; 2) the importance of certain time points in life such as puberty, pregnancy, menopause, and aging; 3) expression and signaling of sex steroid receptors under normal vs. disease states; 4) potential interplay between different sex steroids; 5) the question of whether sex steroids are beneficial or detrimental to the lung; and 6) the potential use of sex steroid signaling as biomarkers and therapeutic avenues in lung diseases. The importance of focusing on sex differences and sex steroids in the lung lies in the increasing incidence of lung diseases in women and the need to address lung diseases across the life span. PMID:22240244

  16. Dual Comb Raman Spectroscopy on Cesium Hyperfine Transitions-Toward a Stimulate Raman Spectrum on CF4 Molecule

    NASA Astrophysics Data System (ADS)

    Liu, Tze-Wei; Hsu, Yen-Chu; Cheng, Wang-Yau

    2015-06-01

    Raman spectroscopy is an important spectroscopic technique used in chemistry to provide a fingerprint by which molecules can be identified. It helps us to observe vibration- rotation, and other low-frequency modes in a system. Dual comb Raman spectroscopy allows measuring a wide bandwidth with high resolution in microseconds. The stimulate Raman spectroscopy had been performed in early days where the nonlinear conversion efficiency depended on laser peak power. Hence we propose an approach for rapidly resolving the Raman spectroscopy of CF4 molecule by two Ti:sapphire comb lasers. Our progress on this proposal will be presented in the conference. First, we have realized a compact dual Ti:sapphire comb laser system where the dual Ti:sapphire laser system possesses the specification of 1 GHz repetition rate. In our dual comb system, 1 GHz repetition rate, 100 kHz Δfrep and 2.4 THz optical filter are chosen according to the demands of our future works on spectroscopy. Therefore, the maximum mode number within free spectral range is 5*103, and the widest range of dual-comb based spectra in that each spectrum could be uniquely identified is 5 THz. The actual bandwidth is determined by the employed optical filter and is set to be 2.4 THz here, so that the corresponding data acquisition time is 10 μs. Secondly, since the identification of the tremendous spectral lines of CF4 molecule relies on a stable reference and a reliable data-retrieving system, we propose a first-step experiment on atomic system where the direct 6S-8S 822-nm two-photon absorption and 8S-6P3/2 (794 nm) enhanced stimulate Raman would be realized directly by using Ti:sapphire laser. We have successfully performed direct comb laser two-photon spectroscopy for both with and without middle-level enhanced. For the level enhanced two-photon spectrum, our experimental setup achieves Doppler-free spectrum and a record narrow linewidth (1 MHz). T.-W. Liu, C.-M. Wu, Y.-C. Hsu and W.-Y. Cheng, Appl. Phys. B 117, 699 (2014) P. Fendel, S. D. Bergeson, Th. Udem, and T. W. Hänsch, Opt. Lett. 32, 701 (2007)

  17. A flexible and ultra-flat optical frequency comb generator using a parallel Mach-Zehnder modulator with a single DC bias

    NASA Astrophysics Data System (ADS)

    Shang, Lei; Li, Yaping; Ma, Liang; Chen, Jun

    2015-12-01

    A flat optical frequency comb generator utilizing a single dual parallel Mach-Zehnder modulator (DPMZM) is detailed investigated both in theory and experiment. In the scheme, the two sub-modulators of DPMZM are biased at the maximum and minimum transmission points respectively. By adjusting the RF signals power, two optical frequency combs with even harmonics or odd harmonics can be generated. So at the end of DPMZM, 5 and 7-line flat OFCs with a side-comb suppression ratio (SCSR) higher than 18 dB are theoretically and experimentally generated. The optical frequency comb generator scheme is relatively simple and valuable due to only one bias voltage may be controlled.

  18. Optical frequency comb generator based on a monolithically integrated passive mode-locked ring laser with a Mach-Zehnder interferometer.

    PubMed

    Corral, V; Guzmán, R; Gordón, C; Leijtens, X J M; Carpintero, G

    2016-05-01

    We report the demonstration of an optical-frequency comb generator based on a monolithically integrated ring laser fabricated in a multiproject wafer run in an active/passive integration process in a generic foundry using standardized building blocks. The device is based on a passive mode-locked ring laser architecture, which includes a Mach-Zehnder interferometer to flatten the spectral shape of the comb output. This structure allows monolithic integration with other optical components, such as optical filters for wavelength selection, or dual wavelength lasers for their stabilization. The results show a -10  dB span of the optical comb of 8.7 nm (1.08 THz), with comb spacing of 10.16 GHz. We also obtain a flatness of 44 lines within a 1.8 dB power variation. PMID:27128043

  19. Honey bees (Apis mellifera) reared in brood combs containing high levels of pesticide residues exhibit increased susceptibility to Nosema (Microsporidia) infection.

    PubMed

    Wu, Judy Y; Smart, Matthew D; Anelli, Carol M; Sheppard, Walter S

    2012-03-01

    Nosema ceranae and pesticide exposure can contribute to honey bee health decline. Bees reared from brood comb containing high or low levels of pesticide residues were placed in two common colony environments. One colony was inoculated weekly with N. ceranae spores in sugar syrup and the other colony received sugar syrup only. Worker honey bees were sampled weekly from the treatment and control colonies and analyzed for Nosema spore levels. Regardless of the colony environment (spores+syrup added or syrup only added), a higher proportion of bees reared from the high pesticide residue brood comb became infected with N. ceranae, and at a younger age, compared to those reared in low residue brood combs. These data suggest that developmental exposure to pesticides in brood comb increases the susceptibility of bees to N. ceranae infection. PMID:22285445

  20. Sex Education with Young Children.

    ERIC Educational Resources Information Center

    Koblinsky, Sally; And Others

    1980-01-01

    Discusses guidelines (developed by the Oregon State University Early Childhood Sex Education Project) for developing teacher-parent cooperation in providing sex education to young children. The guidelines concern how to talk about body differences and body functions; how to deal with masturbation, sex play and obscene language; and how to involve…