Science.gov

Sample records for single journey itineraries

  1. Journeys Unlimited.

    ERIC Educational Resources Information Center

    McLeod, John N.

    "Journeys Unlimited," a piece of theater-in-education performed by Australia's Bouverie St. Theatre-in-Education team during one term in 1979 and described in this paper, formed an integral component of a larger curriculum development program undertaken in Australian primary schools. This analysis of "Journeys Unlimited" is intended to apprehend…

  2. A Journey Through the Mantle Transition Zone Under Western US From Single and Multiple Scattered Waves

    NASA Astrophysics Data System (ADS)

    Tauzin, B.; Trampert, J.; van der Hilst, R.; Wittlinger, G.; Vergne, J.

    2011-12-01

    Using data from the US Transportable Array, we combine observations of P-to-S single and multiple scattered waves to constrain the transition zone (TZ) structure beneath the Western US. From stacking the data by common conversion points along profiles, we produce depth images of seismic discontinuities. Systematic depth and amplitude measurements are performed for the '410', the '660', and some other minor seismic discontinuities identified as sharp reductions of wave velocities at ˜350 km depth (the '350') and ˜590 km depth (the '590'). The Gorda plate, subducted under Northern California, is traced back to the TZ where it seems to flatten and induces, due to cold temperatures or a high water content, a significant uplift of the '410' under Northern Nevada. The geographical maps of the '410'/'660' amplitude/topography reveal an anomalous TZ at the borders between Washington, Oregon and Idaho with: (i) a thickened TZ, (ii) a sharp jump in the topography of the '660' both in a South-North and West-East direction, and (iii) reduced '410' amplitudes at the North. Such anomalous structure might be inherited from the past history of plate subduction/accretion. A thinned TZ under the Yellowstone is likely the result of a deep hot thermal plume. Both the '350' and the '590' negative discontinuities extend over very large areas. They might be related either to an increased water content in the TZ and/or significant amount of oceanic material accumulated through the past 100 My. An estimation of the TZ water content is now possible based on observation of PPS reverberated phases on the '410' and '660' interfaces.

  3. ATIPS: Automatic Travel Itinerary Planning System for Domestic Areas.

    PubMed

    Chang, Hsien-Tsung; Chang, Yi-Ming; Tsai, Meng-Tze

    2016-01-01

    Leisure travel has become a topic of great interest to Taiwanese residents in recent years. Most residents expect to be able to relax on a vacation during the holidays; however, the complicated procedure of travel itinerary planning is often discouraging and leads them to abandon the idea of traveling. In this paper, we design an automatic travel itinerary planning system for the domestic area (ATIPS) using an algorithm to automatically plan a domestic travel itinerary based on user intentions that allows users to minimize the process of trip planning. Simply by entering the travel time, the departure point, and the destination location, the system can automatically generate a travel itinerary. According to the results of the experiments, 70% of users were satisfied with the result of our system, and 82% of users were satisfied with the automatic user preference learning mechanism of ATIPS. Our algorithm also provides a framework for substituting modules or weights and offers a new method for travel planning. PMID:26839529

  4. ATIPS: Automatic Travel Itinerary Planning System for Domestic Areas

    PubMed Central

    2016-01-01

    Leisure travel has become a topic of great interest to Taiwanese residents in recent years. Most residents expect to be able to relax on a vacation during the holidays; however, the complicated procedure of travel itinerary planning is often discouraging and leads them to abandon the idea of traveling. In this paper, we design an automatic travel itinerary planning system for the domestic area (ATIPS) using an algorithm to automatically plan a domestic travel itinerary based on user intentions that allows users to minimize the process of trip planning. Simply by entering the travel time, the departure point, and the destination location, the system can automatically generate a travel itinerary. According to the results of the experiments, 70% of users were satisfied with the result of our system, and 82% of users were satisfied with the automatic user preference learning mechanism of ATIPS. Our algorithm also provides a framework for substituting modules or weights and offers a new method for travel planning. PMID:26839529

  5. The journey

    NASA Astrophysics Data System (ADS)

    Cohen, Lori A.

    1995-12-01

    Kodak Optical Products has embarked on a journey that will ultimately lead to manufacturing excellence and total customer satisfaction. With quality as our compass we have already obtained ISO 9001 and Manufacturing Resource Planning (MRP) II certifications. Seeking and attaining these certifications enabled us to understand and enhance fundamentals relative to the operation of our business. This has provided a solid foundation from which we can launch continuous improvement activities. Now we continue our journey to such destinations as 10X reduction in both defects and cycle time, measuring and reducing our cost of poor quality, and upgrading our quality information system. Our presentation will emphasize our 10X improvement process and how it applies to high-volume production of precision plastic optics.

  6. Fulbrighter's journey.

    PubMed

    Banks, Angela D

    2014-01-01

    This article provides a synopsis of a Fulbright scholar's journey to Jordan, filled with challenges, opportunities, and life-changing experiences. The author received a Fulbright lecturing award for 2011-2012 for the Jordan University of Science and Technology School of Nursing. This manuscript discusses the experience of teaching graduate students in nursing in the Middle East, collaborating with Muslim professors on research projects, and organizing a fundraiser that provided financial support for refugees and disadvantaged students at the university. PMID:25252381

  7. [Therapeutic itineraries of individuals with symptoms of anorexia and bulimia].

    PubMed

    Carvalho, Maria Bernadete de; Val, Alexandre Costa; Ribeiro, Maria Mônica Freitas; Santos, Lúcia Grossi Dos

    2016-08-01

    The scope of this study is to identify and contextualize aspects of the therapeutic itineraries of patients treated at a university medical clinic specialized in nervous anorexia and bulimia. For this purpose, an attempt was made to reconstitute the succession of events triggered in 20 respondents and their families with the classification of anorexia and bulimia as "health problems." The narratives were analyzed in order to link the individual experiences and the social context of their occurrence (organization of health services, characteristics of treatment and medical knowledge and characteristics of contemporary subjectivity), in light of the theoretical studies of Public Health and Psychoanalysis. Data analysis revealed that these itineraries arise from connections and disconnections between two distinct approaches: one that organizes the management of patients and the other governing the conduct of health institutions and families. If the latter presuppose a quest for health, this is not what primarily concerns the individuals in question. Their refusal to moderate their own eating disorders is notable on their itineraries, and indicates the functionality of those practices. Such practices play a part in the reconstruction of their self-images. PMID:27557019

  8. Therapeutic itineraries and explanations for tuberculosis: an indigenous perspective

    PubMed Central

    Nogueira, Laura Maria Vidal; Teixeira, Elizabeth; Basta, Paulo Cesar; da Motta, Maria Catarina Salvador

    2016-01-01

    ABSTRACT OBJECTIVE To analyze explanations for tuberculosis and therapeutic itineraries of Brazilian indigenous people. METHODS Case study with a qualitative-descriptive approach. We conducted semi-structured interviews with 11 Munduruku indigenous, including direct observation of treatment for tuberculosis in the municipality of Jacareacanga, south-western region of the state of Para, Brazil. To identify explanations for tuberculosis and therapeutic itineraries, we performed thematic content analysis. RESULTS Traditional medicine was the first therapeutic option chosen by the indigenous. However, biomedicine was also employed, which indicates a circulation between different therapeutic contexts and health concepts among the Munduruku. The explanations provided ranged from recognition of the signs and symptoms specific to tuberculosis to the attribution of the disease to a spirit that leaves the body and wanders in the woods, returning ill into the body. Unlike the biomedical model, which links tuberculosis transmission strictly to interpersonal contact, in closed spaces without natural lighting and ventilation (preferably domestic environments), the Munduruku associate the disease to an indirect contact between people socially distant (enemies or adversaries) in public and open places. CONCLUSIONS The explanations made by the indigenous are unique and deserve the attention of those who are responsible for developing health public policies, as well as of the teams who work on the villages. To guarantee an efficient control of tuberculosis in these regions, it is necessary that the developed actions integrate biomedicine knowledge and the traditional medicine of the indigenous people, in addition to respecting and welcoming local culture manifestations. PMID:26815161

  9. Goethe's Italian Journey and the geological landscape

    NASA Astrophysics Data System (ADS)

    Coratza, Paola; Panizza, Mario

    2015-04-01

    Over 220 years ago Johann Wolfgang von Goethe undertook a nearly two-years long and fascinating journey to Italy, a destination dreamed for a long time by the great German writer. During his journey from Alps to Sicily Goethe reflects on landscape, geology, morphology of "Il Bel Paese", sometimes providing detailed descriptions and acute observations concerning the great and enduring laws by which the earth and all within it are governed. He was an observer, with the eye of the geologist and landscape painter, as he himself stated, and therefore he had a 360 degree focus on all parts of the territory. From the Brenner Pass to Sicily, Goethe reflects on landscape, contrasting morphologies, the genesis of territories, providing detailed descriptions useful for reconstructing the conditions of the territory and crops of the late 18th century. His diary is a description of the impressions he received from the country and its people, mingled with reflections upon art, science and literature. Goethe studied mineralogical and geological phenomena and drew up notes on the life of the people, the climate and the plants. On various scientific occasions and, in particular, within the framework of the Italian Association "Geologia & Turismo", of the Working Group "Geomorphosites" of the International Association of Geomorphologists and the International Year of Planet Earth, the opportunity to re-examine Goethe's travels in Italy from a geological viewpoint was recognised. In the present paper an attempt was made to reproduce the geotourism itinerary ante litteram of the writer to Italy, one of the most important tourist destination worldwide, thanks to its rich cultural and natural heritage and the outstanding aesthetic qualities of the complex natural landscape. This project was essentially conceived with a twofold purpose. First of all, an attempt was made to reproduce the journey of a great writer, as an example of description of landscape perceived and described as

  10. My Personal Journey

    ERIC Educational Resources Information Center

    Lairson, Storm

    2009-01-01

    The Courageous Journey was, for the author, more than an official state endorsement for the professional position she holds as a district superintendent. It was a personal journey that gave her far more than she can illustrate in her final exhibition to earn her performance-based specialty superintendent endorsement. It began in August of 2005…

  11. Voyager - Humanity's Farthest Journey

    NASA Video Gallery

    After 33 years, NASA's twin Voyager spacecraft are still going strong and still sending home information. This video features highlights of the Voyager journeys to the outer planets, and looks at t...

  12. Itinerary of high density lipoproteins in endothelial cells.

    PubMed

    Perisa, Damir; Rohrer, Lucia; Kaech, Andres; von Eckardstein, Arnold

    2016-02-01

    High density lipoprotein (HDL) and its main protein component apolipoprotein A-I (ApoA-I) have multiple anti-atherogenic functions. Some of them are exerted within the vessel wall, so that HDL needs to pass the endothelial barrier. To elucidate their itinerary through endothelial cells (ECs), we labelled ApoA-I and HDL either fluorescently or with 1.4 nm nanogold and investigated their cellular localization by using immunofluorescent microscopy (IFM) and electron microscopy (EM). HDL as well as ApoA-I is taken up by ECs into the same route of intracellular trafficking. Time kinetics and pulse chase experiments revealed that HDL is trafficked through different vesicles. HDL partially co-localized with LDL, albumin, and transferrin. HDL did not co-localize with clathrin and caveolin-1. Fluorescent HDL was recovered at small proportions in early endosomes and endosome to trans-golgi network vesicles but not at all in recycling endosomes, in late endosomes or lysosomes. EM identified HDL mainly in large filled vesicles which however upon IFM did not colocalize with markers of multivesicular bodies or autophagosomes. The uptake or cellular distribution of HDL was altered upon pharmacological interference with cytochalasine D, colchicine and dynasore. Blockage of fluid phase uptake with Amiloride or EIPA did not reduce the uptake of HDL. Neither did we observe any co-localization of HDL with dextran as the marker of fluid phase uptake. In conclusion, HDL and ApoA-I are internalized and trafficked by endothelial cells through a non-classical endocytic route. PMID:26577406

  13. Women's health in urban Mali: Social Predictors and Health Itineraries

    PubMed Central

    Bove, Riley M; Vala-Haynes, Emily; Valeggia, Claudia

    2013-01-01

    Social and marital factors may influence women's health outcomes. This is of particular relevance in sub-Saharan Africa, where women's health indicators lag behind the rest of the world. Our study examines the impact of social mediators of women's health during key events (pregnancy and illness) in urban Mali. In this cross-sectional study, we interviewed 324 women aged 15-80, living in Bamako, the capital city, in 1999. We used mixed quantitative and qualitative methods to obtain detailed histories of pregnancy and illness during specific time periods preceding the survey. We examined the role of marital factors (polygyny, widowhood), social factors (sources of support and scales derived for social network and social power), and household wealth on women's therapeutic itineraries. We compared the sociodemographic characteristics of our sample with those of the 2001 Mali Demographic and Health Survey and used their data on contraception to enrich analyses. We found that most pregnant women delivered in a health center and most women sought medical care during an illness event. Household wealth influenced illness reporting, and financial concerns were obstacles to medical care. Polygyny was associated with lower prevalence of contraceptive use, lower social power, as well as with less support received during pregnancy from women's husbands and in-laws. Widowhood appeared to increase susceptibility to illness, while decreasing resort to biomedical care. Our social composite scores highlighted differences in healthcare utilization in an urban setting with near-uniform access to biomedical care. We validate the utility of locally-derived composite scores, which may provide a deeper understanding into the social mediation of health outcomes for women. PMID:22818488

  14. The Magnificent Journey.

    SciTech Connect

    United States. Bonneville Power Administration.

    1995-01-01

    The annual run of Northwest salmon--from the vast Pacific Ocean to the mountain streams where their lives began--is one of Nature`s most awe-inspiring events. Now that modern science has discovered some of the salmon`s secrets, their journey seems even more miraculous. So unlikely is the survival of a single returning salmon that Nature compensates heavily. Of the other 3,000 to 7,000 eggs in a nest, only one spawning pair, on average, will make it back. Too much or too little water at hatching can wipe out great swarms of young fish life. Bigger fish, bears, seals--all take their share of salmon. Nature allows for these natural events. But Nature alone cannot make up for what people have done. Dams in the Columbia River Basin have blocked huge areas of the wild salmon`s spawning grounds. Roads and towns sprouted up along rivers and streams. Logging and farming practices fouled rivers and creeks. So did pollution from the cities. And it became too easy to catch fish. Salmon runs became smaller and smaller. Some types of salmon disappeared forever. Having nearly destroyed the salmon, people are now coming to their rescue. Still, important runs of Northwest native salmon are in real danger of extinction. Much remains to be done. This brochure presents a close look at the life of a wild salmon, Oncorhynchus tshawystcha.

  15. Travel itinerary uncertainty and the pre-travel consultation--a pilot study.

    PubMed

    Flaherty, Gerard; Md Nor, Muhammad Najmi

    2016-01-01

    Risk assessment relies on the accuracy of the information provided by the traveller. A questionnaire was administered to 83 consecutive travellers attending a travel medicine clinic. The majority of travellers was uncertain about destinations within countries, transportation or type of accommodation. Most travellers were uncertain if they would be visiting malaria regions. The degree of uncertainty about itinerary potentially impacts on the ability of the travel medicine specialist to perform an adequate risk assessment, select appropriate vaccinations and prescribe malaria prophylaxis. This study reveals high levels of traveller uncertainty about their itinerary which may potentially reduce the effectiveness of their pre-travel consultation. PMID:26782127

  16. Indigenous Population Mobilities and School Achievement: International Educational Research Itineraries, Issues and Implications

    ERIC Educational Resources Information Center

    Danaher, P. A.

    2012-01-01

    This paper situates the articles in this special theme issue of the "International Journal of Educational Research" within the broader global literature regarding the educational experiences and opportunities of mobile communities. The paper distils those articles' contributions to extending current understandings about the specific "itineraries"…

  17. 9 CFR 2.126 - Access and inspection of records and property; submission of itineraries.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... characteristics, species (common or scientific name), sex and age of each animal; and (iii) The names, dates, and... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Access and inspection of records and property; submission of itineraries. 2.126 Section 2.126 Animals and Animal Products ANIMAL AND...

  18. Journey Through the Universe

    NASA Astrophysics Data System (ADS)

    Harvey, J.

    2005-12-01

    Journey through the Universe held its first Journey Week January 21-28, 2005 in Hilo, Hawaii. This ambitious program uses the fi elds of space, earth science and exploration to engage communities with long-term connections to science, mathematics and technology. All content is aligned to state and national education standards. Last year, the Hawaii-based program trained 135 teachers, visited more than 120 classrooms, talked to more than 5,000 students and hosted three family science events for more than 2,500 people. In 2006 the program seeks to reach an additional 8,000 students in public, private and charter schools in North Hawaii.

  19. "Journey to the Stars": Presenting What Stars Are to Global Planetarium Audiences by Blending Astrophysical Visualizations Into a Single Immersive Production at the American Museum of Natural History

    NASA Astrophysics Data System (ADS)

    Emmart, Carter; Mac Low, M.; Oppenheimer, B. R.; Kinzler, R.; Paglione, T. A. D.; Abbott, B. P.

    2010-01-01

    "Journey to the Stars" is the latest and fourth space show based on storytelling from data visualization at the Rose Center for Earth and Space at the American Museum of Natural History. This twenty five minute, full dome movie production presents to planetarium audiences what the stars are, where they come from, how they vary in type and over time, and why they are important to life of Earth. Over forty scientists from around the world contributed their research to what is visualized into roughly fifteen major scenes. How this production is directed into a consolidated immersive informal science experience with learning goals is an integrative process with many inputs and concerns for scientific accuracy. The goal is a seamless merger of visualizations at varying spatial and temporal scales with acuity toward depth perception, revealing unseen phenomena, and the layering of concepts together to build an understanding of stars; to blend our common experience of them in the sky with the uncommon meaning we have come to know through science. Scripted by Louise Gikow who has worked for Children's Television Workshop, narrated by Whoopie Goldberg, and musically scored by Robert Miller, this production strives to guide audiences through challenging scientific concepts by complimenting the natural beauty the subject matter presents with understandable prose and musical grandeur. "Journey to the Stars" was produced in cooperation with NASA's Science Mission Directorate, Heliophysics Division and is in release at major planetariums, worldwide.

  20. A Journey in Leadership

    ERIC Educational Resources Information Center

    Shoop, Robert J.

    2009-01-01

    In 1997, two faculty members at Kansas State University began the process of creating something special and distinctive that never existed before. They clearly understood that they were embarking on a journey that would be exciting, yet not totally within their control. They were passionate about the value of developing a leadership studies…

  1. An Educational Journey

    ERIC Educational Resources Information Center

    Marshall, James D.

    2009-01-01

    In this article, the author provides a self-portrait of his intellectual life. He states that his educational journey has always been something of an ongoing fight from his first day at primary school, to the secondary school curriculum and a social philosophy, and what he learned practically in the Navy. Changing the philosophy curriculum in…

  2. Journeys outside the Classroom

    ERIC Educational Resources Information Center

    Beames, Simon; Ross, Hamish

    2010-01-01

    There is growing support for education that is cross-curricular, locally-relevant and involves a high degree of student responsibility. This investigation examines the perspectives of students who have participated in an outdoor learning programme that is theoretically underpinned by the above themes. "Outdoor Journeys" involves learning about the…

  3. My Holocaust Journey.

    ERIC Educational Resources Information Center

    Glanz, Jeffrey

    2000-01-01

    An education professor whose father was a Holocaust survivor recounts a journey to visit World War II concentration camps in Czechoslovakia, Poland, and Germany. He realized that Nazis were systematic exterminators, and cities had been sanitized to banish unseemly memories. Today vigilance and character education are essential. (MLH)

  4. Journeys through antigravity?

    NASA Astrophysics Data System (ADS)

    Carrasco, John Joseph M.; Chemissany, Wissam; Kallosh, Renata

    2014-01-01

    A possibility of journeys through antigravity has recently been proposed, with the suggestion that Weyl-invariant extension of scalars coupled to Einstein gravity allows for an unambiguous classical evolution through cosmological singularities in anisotropic spacetimes. We compute the Weyl invariant curvature squared and find that it blows up for the proposed anisotropic solution both at the Big Crunch as well as at the Big Bang. Therefore the cosmological singularities are not resolved by uplifting Einstein theory to a Weyl invariant model.

  5. Journey of Ethiopia Astronomy

    NASA Astrophysics Data System (ADS)

    Belay Tessema, Solomon

    2015-08-01

    Ancient astronomy had contributed away for the modern development of astronomy. The history of astronomy development in Ethiopian was liked with different beliefs and culture of the society. The Ethiopians were the first who invented the science of stars, and gave names to the planets, not at random and without meaning, but descriptive of the qualities which they conceived them to possess; and it was from them that this art passed, still in an imperfect state, to the Egyptians. Even though, Ethiopian’s contributions for astronomy in the world were immense but the journey of modern astronomy is still in the infant stage. The modern astronomy and space program in Ethiopia was started in 2004 in well organized form from three individuals to the public. In the past eleven years of journey of astronomy development in Ethiopia was the most challenging from national to international level. After strong struggle of a few committed individuals for the past eleven years the development of astronomy is completely changed from dark age to bright age. This paper will try to address the details of journey of astronomy in Ethiopia.

  6. PREFACE: A Stellar Journey A Stellar Journey

    NASA Astrophysics Data System (ADS)

    Asplund, M.

    2008-10-01

    The conference A Stellar Journey was held in Uppsala, Sweden, 23 27June 2008, in honour of Professor Bengt Gustafsson's 65th birthday. The choice of Uppsala as the location for this event was obvious given Bengt's long-standing association with the city stemming back to his school days. With the exception of a two-year postdoc stint in Copenhagen, five years as professor at Stockholm University and two years as director of the Sigtuna foundation, Bengt has forged his illustrious professional career at Uppsala University. The symposium venue was Museum Gustavianum, once the main building of the oldest university in Scandinavia. The title of the symposium is a paraphrasing of Bengt's popular astronomy book Kosmisk Resa (in English: Cosmic Journey) written in the early eighties. I think this aptly symbolizes his career that has been an astronomical voyage from near to far, from the distant past to the present. The original book title was modified slightly to reflect that most of his work to date has dealt with stars in one way or another. In addition it also gives credit to Bengt's important role as a guiding light for a very large number of students, colleagues and collaborators, indeed for several generations of astronomers. For me personally, the book Kosmisk Resa bears particular significance as it has shaped my life rather profoundly. Although I had already decided to become an astronomer, when I first read the book as a 14-year-old I made up my mind then and there that I would study under Bengt Gustafsson and work on stars. Indeed I have remained true to this somewhat audacious resolution. I suspect that a great number of us have similar stories how Bengt has had a major influence on our lives, whether on the professional or personal level. Perhaps Bengt's most outstanding characteristic is his enthralling enthusiasm. This is equally true whether he is pondering some scientific conundrum, supervising students or performing in front of an audience, be it an

  7. Journey to International Adult Education

    ERIC Educational Resources Information Center

    Sun, Qi

    2005-01-01

    In this article, the author describes her journey to international adult education and shares some lessons learned from her journey. The author developed her interest in international adult education through the Scientific Research Institute of International and Comparative Education (SRIICE) at Beijing Normal University and discovered its…

  8. Canoe Journeys and Cultural Revival

    ERIC Educational Resources Information Center

    Johansen, Bruce E.

    2012-01-01

    For the state of Washington's one-hundredth birthday, in 1989, Native peoples there decided to revive a distinctive mode of transportation--long-distance journeys by canoe--along with an entire culture associated with it. Born as the "Paddle to Seattle," during the past two decades these canoe journeys have become a summertime staple for Native…

  9. Ietoga: Samoan Educators' Educational Journeys

    ERIC Educational Resources Information Center

    O'Regan, Bridget

    2006-01-01

    This thesis explores how a group of senior educators in Samoa undertook their educational journeys. It also traces my cultural and research learning journeys and the pathways I followed as a "palagi" (white person) undertaking cross-cultural research. A holistic and collaborative approach entailed consultation with the community throughout the…

  10. The Long Journey

    NASA Technical Reports Server (NTRS)

    Cameron, W. Scott

    2003-01-01

    In analyzing people's careers it should be define and write down one to three things they must have in an assignment, and as many wants as they wish. Compare people's list to the must and wants of potential assignments we can see if there is match. We should discuss career coaching with another manager. Career development by definition is a long journey. As coach help shape the career of other, it does him no good to forget that his own careers will continue to develop.

  11. PREFACE: A Stellar Journey A Stellar Journey

    NASA Astrophysics Data System (ADS)

    Asplund, M.

    2008-10-01

    The conference A Stellar Journey was held in Uppsala, Sweden, 23 27June 2008, in honour of Professor Bengt Gustafsson's 65th birthday. The choice of Uppsala as the location for this event was obvious given Bengt's long-standing association with the city stemming back to his school days. With the exception of a two-year postdoc stint in Copenhagen, five years as professor at Stockholm University and two years as director of the Sigtuna foundation, Bengt has forged his illustrious professional career at Uppsala University. The symposium venue was Museum Gustavianum, once the main building of the oldest university in Scandinavia. The title of the symposium is a paraphrasing of Bengt's popular astronomy book Kosmisk Resa (in English: Cosmic Journey) written in the early eighties. I think this aptly symbolizes his career that has been an astronomical voyage from near to far, from the distant past to the present. The original book title was modified slightly to reflect that most of his work to date has dealt with stars in one way or another. In addition it also gives credit to Bengt's important role as a guiding light for a very large number of students, colleagues and collaborators, indeed for several generations of astronomers. For me personally, the book Kosmisk Resa bears particular significance as it has shaped my life rather profoundly. Although I had already decided to become an astronomer, when I first read the book as a 14-year-old I made up my mind then and there that I would study under Bengt Gustafsson and work on stars. Indeed I have remained true to this somewhat audacious resolution. I suspect that a great number of us have similar stories how Bengt has had a major influence on our lives, whether on the professional or personal level. Perhaps Bengt's most outstanding characteristic is his enthralling enthusiasm. This is equally true whether he is pondering some scientific conundrum, supervising students or performing in front of an audience, be it an

  12. Learn about and Visit Historic College and University Campuses Using the National Park Service "Discover Our Shared Heritage Travel Itinerary Series"

    ERIC Educational Resources Information Center

    Shull, Carol D.

    2011-01-01

    The National Park Service actively educates the public about registered historic places on college and university campuses and encourages people to visit them through its "Discover Our Shared Heritage Travel Itinerary Series." By featuring the historic buildings and grounds of colleges and universities in the itineraries, the National Park Service…

  13. O'Neill's journey.

    PubMed

    Mandelbaum, George

    2015-01-01

    This paper considers some of the processes through which Eugene O'Neill (1888-1953) dramatically shaped his inner life and through which he created his plays. These processes at their finest are evident in his composition of Long Day's Journey into Night (1941a). During its 21-month composition, the play went through three different versions, as evidenced by the playwright's handwritten and typed materials (O'Neill, unpublished, a, b, c, d). This paper posits that each version reflects O'Neill's changing state of mind as he began to master his instinctual life, developing increasingly rich characters and creating a painful, deeply tragic vision. Thus, this paper shows that O'Neill's great artistic achievement reflected a great psychological one. PMID:25619368

  14. Journey of a Lifetime -- Mars

    NASA Video Gallery

    NASA wants you to be part of the Journey to Mars. Today, NASA is pushing the boundaries of technology and innovation. NASA’s fleet of robotic scientific explorers at Mars are paving the way for hu...

  15. Hero's journey in bifurcation diagram

    NASA Astrophysics Data System (ADS)

    Monteiro, L. H. A.; Mustaro, P. N.

    2012-06-01

    The hero's journey is a narrative structure identified by several authors in comparative studies on folklore and mythology. This storytelling template presents the stages of inner metamorphosis undergone by the protagonist after being called to an adventure. In a simplified version, this journey is divided into three acts separated by two crucial moments. Here we propose a discrete-time dynamical system for representing the protagonist's evolution. The suffering along the journey is taken as the control parameter of this system. The bifurcation diagram exhibits stationary, periodic and chaotic behaviors. In this diagram, there are transition from fixed point to chaos and transition from limit cycle to fixed point. We found that the values of the control parameter corresponding to these two transitions are in quantitative agreement with the two critical moments of the three-act hero's journey identified in 10 movies appearing in the list of the 200 worldwide highest-grossing films.

  16. The journey of integrins and partners in a complex interactions landscape studied by super-resolution microscopy and single protein tracking.

    PubMed

    Rossier, Olivier; Giannone, Grégory

    2016-04-10

    Cells adjust their adhesive and cytoskeletal organizations according to changes in the biochemical and physical nature of their surroundings. In return, by adhering and generating forces on the extracellular matrix (ECM) cells organize their microenvironment. Integrin-dependent focal adhesions (FAs) are the converging zones integrating biochemical and biomechanical signals arising from the ECM and the actin cytoskeleton. Thus, integrin-mediated adhesion and mechanotransduction, the conversion of mechanical forces into biochemical signals, are involved in critical cellular functions such as migration, proliferation and differentiation, and their deregulation contributes to pathologies including cancer. A challenging problem is to decipher how stochastic protein movements and interactions lead to formation of dynamic architecture such as integrin-dependent adhesive structures. In this review, we will describe recent advances made possible by super-resolution microscopies and single molecule tracking approaches that provided new understanding on the organization and the dynamics of integrins and intracellular regulators at the nanoscale in living cells. PMID:26571074

  17. [An analysis of psychosocial care for adolescents in crisis based on their therapeutic itineraries].

    PubMed

    Pereira, Melissa de Oliveira; Sá, Marilene de Castilho; Miranda, Lilian

    2014-10-01

    This study analyzes the care provided to adolescents in crisis in a municipality in Greater Metropolitan Rio de Janeiro, Brazil. The article reports on a qualitative health study that used Therapeutic Itinerary and Life Narratives as the methodological resources. The principal theoretical reference was psychoanalyst René Kaës. Based on the adolescents' own verbal accounts, the study aimed to grasp the collective realities that could potentially shed light on the different types of logic and professional practices applied to care for adolescents in psychosocial crisis situations. The underlying assumption was that an approach to the dialectical nature of the crisis required maintaining a framework that would allow establishing a space for transition within which to develop the necessary conditions for disruptive and paradoxical elements to be elaborated. However, crisis care in the context studied here proved to be hampered by infrastructure issues, institutional rigidity, and fragmentation of activities, with little orientation towards inter-sector work. PMID:25388317

  18. [Influence of social networks on the therapeutic itineraries of people with venous ulcer].

    PubMed

    Da Silva, Dalva Cezar; Budó, Maria De Lourdes Denardin; Schimith, Maria Denise; Torres, Gilson De Vasconcelos; Durgante, Vânia Lúcia; Rizzatti, Salete De Jesus Souza; Simons, Bruna Sodré

    2014-09-01

    The aim of this study was to identify the influence of social networks in the therapeutic itinerary of people affected by venous ulcers. Qualititative research was conducted in the outpatient clinic of a public hospital in Rio Grande do Sul, Brazil. Data were collected from January to February 2013 by means of semi-structured interviews with 14 people affected by venous ulcers. Content analysis provided the following categories: The family worries with me; I get lots of help from friends and neighbours, and I do it myself. Results revealed some elements of social networks that influence choices and continuity of treatment and care of patient with venous ulcers. It is therefore necessary for nurses to familiarize themselves with these social networks and work with them to strengthen the partnership in care. PMID:25508625

  19. [Influence of social networks on the therapeutic itineraries of people with venous ulcer].

    PubMed

    da Silva, Dalva Cezar; Budó, Maria de Lourdes Denardin; Schimith, Maria Denise; Torres, Gilson de Vasconcelos; Durgante, Vânia Lúcia; Rizzatti, Salete de Jesus Souza; Simons, Bruna Sodré

    2014-09-01

    The aim of this study was to identify the influence of social networks in the therapeutic itinerary of people affected by venous ulcers. Qualititative research was conducted in the outpatient clinic of a public hospital in Rio Grande do Sul, Brazil. Data were collected from January to February 2013 by means of semi-structured interviews with 14 people affected by venous ulcers. Content analysis provided the following categories: The family worries with me; I get lots of help from friends and neighbours, and I do it myself. Results revealed some elements of social networks that influence choices and continuity of treatment and care of patient with venous ulcers. It is therefore necessary for nurses to familiarize themselves with these social networks and work with them to strengthen the partnership in care. PMID:25474846

  20. Problems to Problematics: A Journey.

    ERIC Educational Resources Information Center

    Walsh, Anne

    This paper describes the journey of a former female electrician turned technical and further education teacher turned professional development officer who is now completing her PhD. It also describes the challenges she overcame to make the transition from tradesperson to researcher. It is a personal account of discovery. It describes the most…

  1. Seamless patient journeys the goal.

    PubMed

    Wiegand, Chris

    2016-02-01

    Chris Wiegand, CEO of Jibestream, a software development company for digital interactive technologies with bases in Toronto and Arlington, Virginia, explains how technologies including Wi-Fi, GPS, RFID, and Bluetooth LE are enhancing wayfinding in healthcare facilities, and, in the process, simplifying the patient journey and helping reduce the stress and anxiety often associated with a visit to the hospital. PMID:27017656

  2. Understanding ADHD: Our Personal Journey

    ERIC Educational Resources Information Center

    Blahy, Tammy Lynn

    2004-01-01

    No good time exists to face the realities of attention deficit and hyperactivity disorder (ADHD). Children across the United States and Canada are accompanied to clinics and schools by frightened, worried parents. In the book, In Understanding ADHD (2001), Ken and Andrea McCluskey bring to life the realities of the everyday journey of coping with…

  3. My Journey as a Reader

    ERIC Educational Resources Information Center

    Cevellos, Tatiana

    2008-01-01

    In this case history, the author describes how her journey as a reader evolved from a poor reader who did not like to read in elementary school into an avid trilingual reader in graduate school. Once she discovered the joy of reading, each language in which she read had its own purpose and emotional connection. She credits self-selected reading…

  4. Learning to Supervise: Four Journeys

    ERIC Educational Resources Information Center

    Turner, Gill

    2015-01-01

    This article explores the experiences of four early career academics as they begin to undertake doctoral supervision. Each supervisor focused on one of their supervisees and drew and described a Journey Plot depicting the high and low points of their supervisory experience with their student. Two questions were addressed by the research: (1) How…

  5. Journeying "Down the Rabbit Hole"

    ERIC Educational Resources Information Center

    Rossman, Alan; Dummer, John

    2004-01-01

    In describing the professional development journey of science teachers, the National Science Standards (NRC 1996) provides a useful cartography. Inquiry, those standards suggest, is the central strategy for the teaching of science. By illustrating the parallels between inquiry as a form of scientific investigation and inquiry as a classroom…

  6. A District's Journey to Inquiry

    ERIC Educational Resources Information Center

    Keeling, Mary

    2009-01-01

    Students learn best from well-designed instruction. To what extent can a school district design a curriculum that supports inquiry learning? How can a district implement consistent inquiry practices in forty schools? In this article, the author discusses Newport News Public School District's journey to inquiry which began in 2004 with a…

  7. Unsettling care: Troubling transnational itineraries of care in feminist health practices.

    PubMed

    Murphy, Michelle

    2015-10-01

    Responding to the call by Maria Puig de la Bellacasa for Science and Technology Studies to take up 'matters of care', this article cautions against equating care with positive feelings and, in contrast, argues for the importance of grappling with the non-innocent histories in which the politics of care already circulates, particularly in transnational couplings of feminism and health. The article highlights these histories by tracing multiple versions of the politics of care in a select set of feminist engagements with the pap smear and cervical cancer. Drawing on postcolonial and indigenous feminist commitments, as well as amplifying Donna Haraway's call to 'stay with the trouble', the article seeks to disturb hegemonic histories and arrangements of race, colonialism, and political economy, while simultaneously valuing divergent multi-local itineraries as relevant to technoscientific matters of care. This call for a politics of 'unsettling' care strives to stir up and put into motion what is sedimented, while embracing the generativity of discomfort, critique, and non-innocence. PMID:26630818

  8. [Itineraries and methods of illegal abortion in five Brazilian state capitals].

    PubMed

    Diniz, Debora; Medeiros, Marcelo

    2012-07-01

    This paper presents the results of the structured interview phase of the National Abortion Survey (PNA-interviews), describing the itineraries, methods and social and demographic profile of women who had at least one illegal abortion. Structured interviews were conducted during the years 2010 and 2011 in five state capitals (Belem, Brasilia, Porto Alegre, Rio de Janeiro and Salvador) with 122 women aged between 18 and 39 who had abortions. It is a non-probabilistic sample controlled by six parameters in accordance with level of education and age to reflect the social and demographic structure found in the PNA ballot-box questionnaire phase. The majority of women interviewed had had only one abortion, but 1 in every 4 had two abortions and 1 in every 17 had a third one. The majority of abortions are among women under 19 years of age who already had children and a higher incidence is found among black women. The most common test for pregnancy is beta-HCG blood test, the pharmacy urine test and ultrassound. The prevailing method for induction is a combination of teas and misoprostol (called Cytotec in Brazil), followed by hospital assistance after induction. Women are usually helped by a relative or their partners and several women reported helping other women to have abortions. PMID:22872325

  9. Eva & Rick's Incredible Journey

    ERIC Educational Resources Information Center

    Carner, Eva

    2006-01-01

    In 1982, the author became the foster mom to Rick, a small child who got a pretty rough start to life and an even rougher "pre" start. Rick's birth mother was addicted to alcohol and for most of his time in her womb she drank heavily. The author was a single, special education teacher, and worked with children with developmental disabilities for…

  10. Hawaii's Annual Journey through the Universe Program

    NASA Astrophysics Data System (ADS)

    Harvey, J.; Michaud, P.

    2013-04-01

    Hawaii's eighth annual Journey through the Universe, Gemini North's flagship local outreach program, engaged local as well as a host of visiting astronomy educators from across the country. Seventy-two educators enlightened over 8,000 students at 20 schools while visiting over 380 classrooms during “Journey Week” 2012. Gemini and the local observatories on Mauna Kea, the National Lunar Science Institute, the University of Hawai‘i at Hilo, ‘Imiloa Astronomy Education Center and Hawaii's Department of Education made this possible and are currently working to further extend the Journey program. The next phase of the nationally recognized educational outreach initiative, Journey 2.0, continues to include assessment and will explore the viability of funding for longitudinal studies on both students and teachers. New in 2012, we invited the public to join the astronomers, teacher and principals for a one-day STEM workshop which featured a keynote address: “Science—It's Not a Book of Knowledge… It's a Journey” led by Dr. Jeff Goldstein, Director of the National Center for Earth and Space Science Education and founder of the national Journey through the Universe program. The 2013 Journey program is scheduled for March 7-13, 2013. More information for this program can be found online at www.gemini.edu/journey.

  11. Shakespeare's Improbable Journey to Inner Mongolia

    ERIC Educational Resources Information Center

    Isenberg, Richard

    2008-01-01

    The author has written about his journey to Inner Mongolia, where he helped university students mount a production of a Shakespeare play, which led him to reflect on an earlier, perhaps even more improbable journey. He then describes his growth from a student with dyslexia into a teacher, and principal as the result of guidance and encouragement…

  12. Cell itinerary and metabolic fate of proinsulin in rat liver: in vivo and in vitro studies.

    PubMed

    Desbuquois, Bernard; Chauvet, Geneviève; Kouach, Mostafa; Authier, François

    2003-12-01

    Proinsulin, the insulin precursor in pancreatic beta-cells, displays a slower hepatic clearance than insulin and exerts a more prolonged metabolic effect on liver in vivo. To elucidate the mechanisms underlying these differences, the cellular itinerary and processing of proinsulin and insulin in rat liver have been comparatively studied using cell fractionation. As [125I]-insulin, [125I]-proinsulin taken up into liver in vivo was internalized and accumulated in endosomes, in which it underwent dissociation from the insulin receptor and degradation in a pH- and ATP-dependent manner. However, relative to [125I]-insulin, [125I]-proinsulin showed a delayed and prolonged in vivo association with endosomes, a slower in vivo and cell-free endosomal processing, and a higher cell-free endosome-lysosome transfer. Endosomal extracts degraded to a lesser extent proinsulin than insulin at acidic pH; so did, and even proportionally less, at neutral pH, plasma membrane and cytosolic fractions. Proinsulin degradation products generated by soluble endosomal extracts were isolated by HPLC and characterized by mass spectrometry. Under conditions resulting in multiple cleavages in insulin, proinsulin was cleaved at eight bonds in the C peptide but only at the Phe24-Phe25 bond in the insulin moiety. As native insulin, native proinsulin induced a dose- and time-dependent endocytosis and tyrosine phosphorylation of the insulin receptor; but at an inframaximal dose, proinsulin effects on these processes were of longer duration. We conclude that a reduced proteolysis of proinsulin in endosomes, and probably also at the plasma membrane, accounts for its slower hepatic clearance and prolonged effects on insulin receptor endocytosis and tyrosine phosphorylation. PMID:12970169

  13. Journey to a Comet (Animation)

    NASA Technical Reports Server (NTRS)

    2005-01-01

    [figure removed for brevity, see original site] Quick Time Movie for PIA02117 Journey to a Comet

    This movie shows Deep Impact's approach to comet Tempel 1. It is made up of images taken by the spacecraft's medium-resolution camera from May 1 to July 2, 3:50 Universal Time. The spacecraft detected three outbursts during this time period, on June 14, June 22 and July 2. The outbursts appear as flickers or bursts of light. The movie ends during the middle of the final outburst.

  14. Environmental Conditions around Itineraries to Destinations as Correlates of Walking for Transportation among Adults: The RECORD Cohort Study

    PubMed Central

    Karusisi, Noëlla; Thomas, Frédérique; Méline, Julie; Brondeel, Ruben; Chaix, Basile

    2014-01-01

    Introduction Assessing the contextual factors that influence walking for transportation is important to develop more walkable environments and promote physical activity. To advance previous research focused on residential environments and overall walking for transportation, the present study investigates objective environmental factors assessed around the residence, the workplace, the home – work itinerary, and the home – supermarket itinerary, and considered overall walking for transportation but also walking to work and to shops. Methods Data from the RECORD Study involving 7290 participants recruited in 2007–2008, aged 30–79 years, and residing in the Paris metropolitan area were analyzed. Multilevel ordinal regression analyses were conducted to investigate environmental characteristics associated with self-reported overall walking for transportation, walking to work, and walking to shops. Results High individual education was associated with overall walking for transportation, with walking to work, and walking to shops. Among workers, a high residential neighborhood education was associated with increased overall walking for transportation, while a high workplace neighborhood education was related to an increased time spent walking to work. The residential density of destinations was positively associated with overall walking for transportation, with walking to work, and with walking to shops, while the workplace density of destinations was positively associated with overall walking for transportation among workers. Environmental factors assessed around the itineraries were not associated with walking to work or to the shops. Conclusion This research improves our understanding of the role of the environments on walking for transportation by accounting for some of the environments visited beyond the residential neighborhood. It shows that workers' walking habits are more influenced by the density of destinations around the workplace than around the

  15. Hawaii's Annual Journey Through the Universe Program

    NASA Astrophysics Data System (ADS)

    Harvey, J.; Daou, D.; Day, B.; Slater, T. F.; Slater, S. J.

    2012-08-01

    Hawaii's annual Journey through the Universe program is a flagship Gemini public education and outreach event that engages the public, teachers, astronomers, engineers, thousands of local students and staff from all of the Mauna Kea Observatories. The program inspires, educates, and engages teachers, students, and their families as well as the community. From February 10-18, 2011, fifty-one astronomy educators from observatories on Mauna Kea and across the world visited over 6,500 students in 310 classrooms at 18 schools. Two family science events were held for over 2,500 people at the 'Imiloa Astronomy Education Center and the University of Hawaii at Hilo. The local Chamber of Commerce(s) held an appreciation celebration for the astronomers attended by over 170 members from the local government and business community. Now going into its eighth year in Hawaii, the 2012 Journey Through the Universe program will continue working with the observatories on Mauna Kea and with the NASA Lunar Science Institute (NLSI). As a new partner in our Journey program, NLSI will join the Journey team (Janice Harvey, Gemini Observatory, Journey Team Leader) and give an overview of the successes and future developments of this remarkable program and its growth. The future of America rests on our ability to train the next generation of scientists and engineers. Science education is key and Journey through the Universe opens the doors of scientific discovery for our students. www.gemini.edu/journey

  16. Ecomuseum itineraries, a path of rediscovery and enhancement of the territory

    NASA Astrophysics Data System (ADS)

    La Longa, Federica; Lanza, Tiziana; Crescimbene, Massimo

    2013-04-01

    globalization takes us to lose sight of the concept of place in favor of the non-place, an environment free of characteristics and boundaries. This trend, if on one hand helps to share problems and solutions related to environmental protection, other hand risks producing a variety of effects that lead communities to disown the values of their territory. Instead the experience realized takes us in an opposite direction. We believe that educational projects structured on eco museum itineraries can promote in young people an experiential path of rediscovery and enhancement of the territory (genius loci). The active techniques used in the project (dramatization, creative writing, music, etc.) favored boys in the acquisition of knowledge and skills that allow enhance of territorial resources and sharing it with the community.

  17. Between flows and therapeutic projects: revisiting the notions of lines of care in health and therapeutic itineraries.

    PubMed

    Silva, Neide Emy Kurokawa E; Sancho, Leyla Gomes; Figueiredo, Wagner dos Santos

    2016-03-01

    This essay discusses the possibilities of conceptual and practical connections between the ideas of line of care and therapeutic itineraries, beginning with the theoretical contributions that lay the foundations for the Line of Integrated Healthcare and the hermeneutic approaches to Care. The implementation of lines of care tuned to individual and collective health needs can be glimpsed in the construction of therapeutic projects, inasmuch as they privilege the particularities of each situation in the agreement of flows of appointments, exams, and other procedures. The therapeutic project - taken as an arrangement, strategy, device, or basic dimension of Care in the work process in health - can be seen as an image that lays out a possibility of the future, which in turn is a projection conditioned by past experiences of health, illness, and life. From the criticism of explanatory models, preponderant in the studies of therapeutic itineraries, we defend the investment in approaches that privilege interpretation and understanding, capable of recuperating, contextualizing, and reconstructing trajectories, beginning with the subjects involved in the care process. PMID:26960096

  18. Identity, storytelling and the philanthropic journey

    PubMed Central

    Maclean, Mairi; Harvey, Charles; Gordon, Jillian; Shaw, Eleanor

    2015-01-01

    This article develops theoretical understanding of the involvement of wealthy entrepreneurs in socially transformative projects by offering a foundational theory of philanthropic identity narratives. We show that these narratives are structured according to the metaphorical framework of the journey, through which actors envision and make sense of personal transformation. The journey provides a valuable metaphor for conceptualizing narrative identities in entrepreneurial careers as individuals navigate different social landscapes, illuminating identities as unfolding through a process of wayfinding in response to events, transitions and turning-points. We delineate the journey from entrepreneurship to philanthropy, and propose a typology of rewards that entrepreneurs claim to derive from giving. We add to the expanding literature on narrative identities by suggesting that philanthropic identity narratives empower wealthy entrepreneurs to generate a legacy of the self that is both self- and socially oriented, these ‘generativity scripts’ propelling their capacity for action while ensuring the continuation of their journeys. PMID:26456976

  19. Design Principles and First Educational Experiments of pR, a Platform to Infer Geo-Referenced Itineraries from Travel Stories

    ERIC Educational Resources Information Center

    Loustau, Pierre; Nodenot, Thierry; Gaio, Mauro

    2009-01-01

    Purpose: The purpose of this paper is to present a computational approach and a toolset to infer spatial displacements as they occur in route narrative documents and report on first experiments done to produce computer-aided learning (CAL) applications and instructional design editors that exploit the inferred georeferenced itineraries.…

  20. "Seeing the Trees Not Just the Wood": Steps and Not Just Journeys in Teacher Action Research

    ERIC Educational Resources Information Center

    Casey, Ashley

    2013-01-01

    Either action research by teachers uses the approach as a methodology to examine pedagogical change in a single intervention or it is used as means of understanding a journey of change. In contrast, this paper examines the significant impact of using action research in a second cycle of learning in the same context and with the same participants.…

  1. The Journey Is the Film Is the Journey: Michael Winterbottom's "In This World"

    ERIC Educational Resources Information Center

    Farrier, David

    2008-01-01

    This essay examines Michael Winterbottom's 2002 film "In This World," which follows the journey of two Afghan migrants from Peshawar to London. Winterbottom's preparation involved travelling from London to Peshawar and then in reverse overland as far as Istanbul; he then returned to Peshawar and filmed the same journey using two non-professional…

  2. Geotourist itineraries along the Italian territory: examples of mapping the geoheritage in different geomorphological and historical contexts

    NASA Astrophysics Data System (ADS)

    Panizza, Valeria; Brandolini, Pierluigi; Laureti, Lamberto; Nesci, Olivia; Russo, Filippo; Savelli, Daniele

    2016-04-01

    In the framework of the studies dealing with geomorphosites mapping, many researches were carried out in the last years presenting both applied examples and proposals for tourist fruition. Researchers had to face many different challenges in transferring the knowledge about the geomorphological heritage on maps. The most relevant are those concerning the use of maps for tourist promotion, taking into account the requirements of clearness of representation of landforms and also the need of pointing out possible geomorphological hazards along tourist paths. Within the activity of the Working Group "Geomorphosites and Cultural Landscape" of AIGeo (Italian Association of Physical Geography and Geomorphology), some Italian itineraries, focused on the promotion of the geomorphological heritage by means of geotourist maps, are presented. They have the goal of: promoting landscape through its geomorphological and geological heritage; disseminating geoheritage knowledge focusing its relationships with cultural landscape and human history; assessing geomorphological hazards and possible risk situations The proposed itineraries are localised in different Italian regions and they concern: - the area around the remains of the Roman town of Ostra. The town is placed on the left side of the Misa River (Marche region, Italy), atop a stream terrace dating back to the uppermost Pleistocene-early Holocene. Detailed geomorphological field and remote-sensing mapping started in 2015. The surveying is aimed at focusing the geomorphological evolution as well as at assessing possible geomorphological hazard for both conservation and exploitation scopes. A geotourist trail is proposed with the aim of highlighting and integrating geomorphological and archaeological elements and information. - a geotourist trail along the coastal terraced slopes of Cinque Terre (Liguria, NW Italy): worldwide considered as one of the most outstanding examples of human integration with the natural landscape

  3. Journey through Bui-Bui

    NASA Astrophysics Data System (ADS)

    MacArthur, Ana C.

    2000-10-01

    In a continuation of my search for an understanding of sunlight's relationship to the health of the human organism, I created the installation A Journey Through Bui-Bui; Lifting the Purdah of Mal-Illumination. It was exhibited in 1999 at The Museum of Fine Arts, Santa Fe, New Mexico. The entire work pivots around the image of the veil worn by Muslim women, as both content and metaphor related to the issue of the absence or presence of light in the physical body. The following paper will discuss the development of concepts and the technical progression of this recently completed large-scale mixed media work. This three-roomed installation integrated life casts of the human figure covered in veils, various sculptural elements, fiber optics, and dichromated gelatin (DCG) holograms. The DCG holographic glass objects were produced with an array of glass sculpting tools. I will also briefly discuss current work evolving out of this installation, which further explored the sculptural possibilities of glass and the coating and recording of DCG on curved surfaces.

  4. Cultural Competence: A Journey to an Elusive Goal

    ERIC Educational Resources Information Center

    Saunders, Jeanne A.; Haskins, Motier; Vasquez, Matthew

    2015-01-01

    To develop cultural competence, one must undertake an elusive journey that likely has no destination. Social workers have a responsibility to undertake this often rocky journey with few guideposts. As educators of future professionals, schools of social work must ensure that their students begin, or continue, this journey during this time of…

  5. Travelling Far--Drawing Closer: Journeys That Shape Identity

    ERIC Educational Resources Information Center

    Schatz-Oppenheimer, Orna; Kalnisky, Esther

    2014-01-01

    This article presents findings from a qualitative narrative research study conducted during a journey to Ethiopia undertaken by graduates of an academic program in Israel in 2005. The study focuses on the significance of the journey as a process that helped reconstruct their identity. During the journey, twelve Ethiopian education graduates were…

  6. Journey of a molecular biologist.

    PubMed

    Nomura, Masayasu

    2011-01-01

    My journey into a research career began in fermentation biochemistry in an applied science department during the difficult post-World War II time in Japan. Subsequently, my desire to do research in basic science developed. I was fortunate to be a postdoctoral fellow in the United States during the early days of molecular biology. From 1957 to 1960, I worked with three pioneers of molecular biology, Sol Spiegelman, James Watson, and Seymour Benzer. These experiences helped me develop into a basic research scientist. My initial research projects at Osaka University, and subsequently at the University of Wisconsin, Madison, were on the mode of action of colicins as well as on mRNA and ribosomes. Following success in the reconstitution of ribosomal subunits, my efforts focused more on ribosomes, initially on the aspects of structure, function, and in vitro assembly, such as the construction of the 30S subunit assembly map. After this, my laboratory studied the regulation of the synthesis of ribosomes and ribosomal components in Escherichia coli. Our achievements included the discovery of translational feedback regulation of ribosomal protein synthesis and the identification of several repressor ribosomal proteins used in this regulation. In 1984, I moved to the University of California, Irvine, and initiated research on rRNA transcription by RNA polymerase I in the yeast Saccharomyces cerevisiae. The use of yeast genetics combined with biochemistry allowed us to identify genes uniquely involved in rRNA synthesis and to elucidate the mechanism of initiation of transcription. This essay is a reflection on my life as a research scientist. PMID:21456966

  7. Mount Sinai Hospital's journey into TQM.

    PubMed

    Freedman, T; Mapa, J; Droppo, L

    1994-01-01

    Toronto's Mount Sinai Hospital commenced its total quality management journey in the late 1980s as a complement to its extensive experience in quality assurance. This article focuses on Phase I--the process of setting up teams. This phase includes project nomination and selection; team membership selection and education; and the quality improvement process. The authors share the lessons they learned during the course of the journey and present the directions that TQM at Mount Sinai will take in the future. PMID:10133636

  8. Life's Journey Leads to Founding a Company

    ERIC Educational Resources Information Center

    Richardson, Ginny

    2006-01-01

    This profile highlights Dawn Zibricky, who founded Provide Care for Life. Its mission is to "embrace the journey of families living with and caring for an individual with special needs. Through partnership and collaboration, Provide Care for Life helps families meet the future with security, dignity and grace." This organization was the…

  9. Learning through the Ages: An Epistemological Journey

    ERIC Educational Resources Information Center

    Reid, J. Courtney

    2009-01-01

    This paper explores how three nineteenth-century women writers guided my thinking about education, oppression and spirituality during different decades of my twentieth-century life. In order to re-collect my epistemological journey, a process that requires analysis and reflection, the paper combines the critical lens of feminist theory with the…

  10. Journey toward Teaching Mathematics through Problem Solving

    ERIC Educational Resources Information Center

    Sakshaug, Lynae E.; Wohlhuter, Kay A.

    2010-01-01

    Teaching mathematics through problem solving is a challenge for teachers who learned mathematics by doing exercises. How do teachers develop their own problem solving abilities as well as their abilities to teach mathematics through problem solving? A group of teachers began the journey of learning to teach through problem solving while taking a…

  11. One Teacher's Journey through the Mediated Intersections

    ERIC Educational Resources Information Center

    Beach, Crystal L.

    2015-01-01

    Today's classrooms often have a plethora of new ways of reading and writing entering the room, but too often these new ways of "doing" are disregarded and checked at the door. For this reason, one educator shares her journey through the mediated intersections of media, culture, and education. In this piece, she explores how literacy…

  12. The APPA Journey and RMA Fourteeners Club

    ERIC Educational Resources Information Center

    Morris, John P.

    2012-01-01

    The APPA journey represents a continuum through one's career in educational facilities management. Early in one's career, APPA can assist with professional development such as the Facilities Drive-In Workshop, the Supervisor's Toolkit, the APPA Institute for Facilities Management, and the APPA Leadership Academy. APPA provides for both…

  13. Learning to Read: A Professional Learning Journey

    ERIC Educational Resources Information Center

    Rennie, Jennifer

    2011-01-01

    This article reports on a study that investigated a professional development initiative in Australia to address a decline in reading comprehension scores in the middle and upper years of Primary school. It describes the professional learning journey of a middle primary teacher and his literacy coach over a period of 12 months as they worked to…

  14. "The Secret Garden": A Literary Journey.

    ERIC Educational Resources Information Center

    Jordan, Anne Devereaux

    1998-01-01

    Outlines the life of Frances Hodgson Burnett, author of "The Secret Garden." Argues that it not only tells an enthralling tale, but takes readers on a journey through the history of English literature. Discusses the gothic tradition and romanticism of "The Secret Garden." Lists classic elements in the book and offers five ideas for stimulating…

  15. Chinese Learning Journeys: Chasing the Dream

    ERIC Educational Resources Information Center

    Su, Feng, Ed.

    2011-01-01

    Eight students from mainland China chart their learning journeys across national and continental boundaries and socio-cultural contexts. The five women and three men structure their experiences of studying in China and the West around the turning points and life changing choices they made in chasing their dreams. They embody its emergent…

  16. A Journey from Coercion to Building Courage

    ERIC Educational Resources Information Center

    DeSalvatore, Gino; Millspaugh, Carla; Long, Cindy

    2009-01-01

    Historically, behavior management in treatment settings has focused on external controls such as points, tokens, and level systems. This article describes one program's transformation where troubled youth develop internal controls and become active participants in their own change. The authors describe their program's journey to help troubled and…

  17. My Journey with Inquiry-Based Learning

    ERIC Educational Resources Information Center

    Gonzalez, Joseph J.

    2013-01-01

    The author chronicles his experiments with inquiry-based learning (IBL) as he applied lessons from the literature and assessed the results. He describes a difficult journey with the result that, with the help of the literature, supportive colleagues and patient, creative students, he learned how to design courses that invite undergraduates to…

  18. My Long Journey from Suffering to Life

    ERIC Educational Resources Information Center

    Deng, Santino Atem

    2006-01-01

    Santino Atem Deng, one of the '"lost" boys from Sudan, recounts his story of trauma and resilience, when as a nine-year-old, he fled from the civil war in his home country of southern Sudan. Separated from his parents, he joined a group of adults who were able to take care of him and other young people as they journeyed to Ethiopia. Deng tells of…

  19. A Reflection on a Data Curation Journey

    PubMed Central

    van Zyl, Christa

    2015-01-01

    This commentary is a reflection on experience of data preservation and sharing (i.e., data curation) practices developed in a South African research organization. The lessons learned from this journey have echoes in the findings and recommendations emerging from the present study in Low and Middle-Income Countries (LMIC) and may usefully contribute to more general reflection on the management of change in data practice. PMID:26297756

  20. The promotion of geotourism in protected areas: a proposal of itinerary through the Matese Massif (Campania and Molise regions, Italy).

    NASA Astrophysics Data System (ADS)

    Rosskopf, Carmen Maria; Filocamo, Francesca; Amato, Vincenzo; Cesarano, Massimo

    2016-04-01

    success. Meanwhile, there are various initiatives that promote geotourism separately in the Molise and Campania sectors. However, a network of geotourism initiatives linking the two sectors and allowing the exploitation of the geological heritage of the Matese area as a whole is still lacking. Aim of this study is, obviously, the promotion of the geoheritage of the Matese Massif. Specific objects are to contribute to a better connectivity between its two sectors, the development of an overall geotourism network and, somehow, the establishment of the Matese National Park/Geopark. We propose a first geological itinerary that runs through the entire Matese Massif, from south to north. The proposed itinerary includes geosites of local to national relevance and various scientific interest (from Paleontology to Geomorphology). It allows also non-scientific audiences to understand the main steps of the rich geological history of the Matese Mountains and the geomorphic processes that have given rise to the high variety of paleo- and active landscapes and landforms, but also to appreciate its natural heritage.

  1. One Way or Return? The Journey from Practitioner to Researcher

    ERIC Educational Resources Information Center

    Buoro, Ivano

    2015-01-01

    The journey from VET practitioner to academic researcher is not an easy one, especially for VET teachers whose educational research training in action and ethnographic research have been inculcated through years of practice. This paper discusses the highlights of the journey from practitioner to practitioner researcher including a discussion of…

  2. First Person, First Peoples: A Journey through Boundaries

    ERIC Educational Resources Information Center

    Kerr, Sandy

    2006-01-01

    This article documents the author's personal journey as a new evaluator traversing paradigms, continents, and timelines on a quest to discover how best to practice evaluation for the benefit of Maori people (indigenous to New Zealand). The journey has taken the author to a number of evaluation conferences in Australasia and North America, which…

  3. Spiritual Borderlands: A Black Gay Male College Student's Spiritual Journey

    ERIC Educational Resources Information Center

    Means, Darris R.; Jaeger, Audrey J.

    2015-01-01

    This case study explored the spiritual journey and spaces of one Black gay male college student. Data collection included semi-structured interviews, field observations, and photovoice. Findings indicate that the student experienced tension during his spiritual journey because of his racial and sexual orientation identities but was able to…

  4. The Journey of Two Latino Educators: Our Collective Resilience

    ERIC Educational Resources Information Center

    Ramirez, Pablo C.; De La Cruz, Yolanda

    2016-01-01

    This article represents a journey into education undertaken by two Latino educators from diverse generations. Through the content of the narratives, we emphasize that success was achieved within the presence of oppression. The narratives reveal significant constructs that shaped our journey. For the first author, Pablo, role models, pivotal…

  5. Thinking Journey--A New Mode of Teaching Science

    ERIC Educational Resources Information Center

    Schur, Yaron; Galili, Igal

    2009-01-01

    Thinking Journey is introduced as a mode of science instruction based on a specially designed discussion between students and teachers in the context of an imaginary journey. The paper elaborates the rationale of this mode and its specific features: enculturation into science, analytical observation, multiple perspectives of the subject and…

  6. The Educational Journey of a Latina Feminist Community Psychologist

    ERIC Educational Resources Information Center

    Guzman, Bianca

    2012-01-01

    This narrative describes how my educational journey led me to become a Latina feminist community psychologist. My experiences as a Central American woman living in the United States has made me deeply committed to feminist community values and the importance of social justice. Throughout the journey, I connect how immigration status, culture, and…

  7. Spiritual journeys in aging: A buddhist view.

    PubMed

    Nakasone, R Y

    1994-09-01

    The spiritual journey of a Buddhist devotee is a continual exploration of the truth of interdependence which Siddhartha Gautama realized to become the Buddha, "the Enlightened One." On the morning of the enlightenment, the Buddha apprehended the truth that all things and all beings are interconnected and mutually dependent in time and space. One measure of the spiritual maturity of the Buddhist devotee is his or her appreciation for the profound responsibilities and gratitude we share for all things. To illustrate the significance of interdependence in our lives, the author turns to the wisdom contained inVital Involvement in Old Age by Erik and Joan Erikson and Helen Q. Kivnick. PMID:24264030

  8. A complex journey: transmission of microbial symbionts

    PubMed Central

    Bright, Monika; Bulgheresi, Silvia

    2010-01-01

    The perpetuation of symbioses through host generations relies on symbiont transmission. Horizontally transmitted symbionts are taken up from the environment anew by each host generation, and vertically transmitted symbionts are most often transferred through the female germ line. Mixed modes also exist. In this Review we describe the journey of symbionts from the initial contact to their final residence. We provide an overview of the molecular mechanisms that mediate symbiont attraction and accumulation, interpartner recognition and selection, as well as symbiont confrontation with the host immune system. We also discuss how the two main transmission modes shape the evolution of the symbiotic partners. PMID:20157340

  9. A personal journey with matrix metalloproteinases.

    PubMed

    Nagase, Hideaki

    2016-09-01

    I was given the honor of delivering the 2015 Lifetime Membership Award lecture at the International Proteolysis Society's annual meeting held in Penang, Malaysia in October 2015. It gave me an opportunity to look back on how I started my research on matrix metalloproteinases (MMPs) and how I continued to work on these proteinases for the next 42 years. This is a series of sketches from the personal journey that I took with MMPs, starting from the purification of metalloproteinases, cloning, structural studies, then to a more recent encounter, endocytic regulation of matrix-degrading metalloproteinases. PMID:27341559

  10. Journeying as Religious Education: The Shaman, the Hero, the Pilgrim, and the Labyrinth Walker

    ERIC Educational Resources Information Center

    Senn, Corelyn F.

    2002-01-01

    In this article the author looks at the image of journey and its archeform, quest, and finds two spiritual concepts: that of movement to the center followed by a return, and the concomitant understanding that all that has arisen and reached maturity must return to renew itself. Four journeys, the shamanic journey of soul, the hero's journey of…

  11. Journey to the center of the galaxy

    SciTech Connect

    Chaisson, E.

    1980-08-01

    The solar system is a member of the Orion Arm of the Milky Way, far from the center of the Galaxy. This article takes the reader on a hypothetical journey from the solar system to the center of the Galaxy. Results from radio and infrared studies are used to suggest what such a journey might reveal. Traveling from the solar system toward the center, one crosses the Cygnus Arm, then the Sagittarius Arm, and then the so-called Three-kiloparsec Arm. The Arms contain a mixture of young stars as well as lots of gas and dust. Radio studies show that the Three-kiloparsec Arm is more like a ring than an arm. Inside this ring, is another ring composed of giant molecular clouds. Radio and infrared astronomers have discovered that the heart of the Galaxy is composed of matter in most perplexing states. There are three regions known within this innermost thousand light-years. First, there is a large zone of thin, hot ionized gas. Within this, there is a whirlpool of dense, warm matter. And further embedded, there seems to be a small supermassive object at the center. Possibly this object could be a blackhole. Researchers are continuing to examine, monitor, and model this mysterious region, the galactic nuclei. (SC)

  12. The charismatic journey of mastery learning.

    PubMed

    Inui, Thomas S

    2015-11-01

    A collection of articles in this issue examine the concept of mastery learning, underscoring that our journey is from a 19th-century construct for assuring skill development (i.e., completing a schedule of rotations driven by the calendar) to a 21st-century sequence of learning opportunities focused on acquiring mastery of special key competencies within clerkships or other activities. Mastery learning processes and standards have the potential to clarify learning goals and competency measurement issues in medical education. Although mastery learning methods originally focused on developing learners' competency with skillful procedures, the author of this Commentary posits that mastery learning methods may be usefully applied more extensively to broader domains of skillful practice, especially those practices that can be linked to outcomes of care. The transition to mastery-focused criteria for educational advancement is laudatory, but challenges will be encountered in the journey to mastery education. The author examines several of these potential challenges, including expansion of mastery learning approaches to effective but relational clinician advice-giving and counseling behaviors, developing criteria for choosing critical competencies that can be linked to outcomes, avoiding a excessively fragmented approach to mastery measurement, and dealing with "educational comorbidity." PMID:26375264

  13. The Ice: A Journey to Antarctica

    NASA Astrophysics Data System (ADS)

    Ford, Arthur B.

    The title is misleading for a non—“OAE” (Old Antarctic Explorer, to whom “The Ice” is Antarctica) because The Ice is about far more than just ice. It does indeed cover just about all you'd want to know (or more) about Antarctic ice, from the vast south polar sheets and glaciers to the great tabular bergs, bergy bits, brash ice, pancake ice, frazil ice, and the pack of the polar seas; but it also explores nearly every aspect of this “Last of Lands” in an unusually comprehensive coverage. From the “Heroic Ages” of early 20th-century explorers Robert Scott, Ernest Shackleton, and Roald Amundsen to the present “Cruise Ship Age,”Antarctica has produced a wealth of literature in the “Journey to…” style — which Pyne's is not. Instead, his product from one short (3-month) visit under a National Endowment for the Humanities fellowship takes all readers o n a webwork journey through time, space, ice, and rocks for an appreciation of “ The Ice” in a way found in no other book. This, his fifth book (another one is Fire in America, Princeton University Press, Princeton, N.J., 1982), is a significant contribution to the literature of Antarctica. Pyne's prose cannot be paraphrased for a review, as the reader will be able to appreciate from the excerpts to follow.

  14. Phenolic compounds: their journey after intake.

    PubMed

    Velderrain-Rodríguez, G R; Palafox-Carlos, H; Wall-Medrano, A; Ayala-Zavala, J F; Chen, C-Y O; Robles-Sánchez, M; Astiazaran-García, H; Alvarez-Parrilla, E; González-Aguilar, G A

    2014-02-01

    Plant foods are rich in phenolic compounds (PCs) that display multifaceted bioactions in health promotion and disease prevention. To exert their bioactivity, they must be delivered to and absorbed in the gastrointestinal (GI) tract, transported in circulation, and reach the target tissues. During the journey from ingestion to target tissues and final excretion, PCs are subjected to modifications by many factors during their absorption, deposition, metabolism and excretion (ADME) and consequently their bioefficacy may be modified. Consistent with all nutrients in foods, PCs must first be released from the food matrix through mechanical, chemical, and enzymatic forces to facilitate absorption along the GI tract, particularly in the upper small intestine section. Further, glycosylation of PCs directs the route of their absorption with glycones being transported through active transportation and aglycones through passive diffusion. After enteral absorption, the majority of PCs are extensively transformed by the detoxification system in enterocytes and liver for excretion in bile, feces, and urine. The journey of PCs from consumption to excretion appears to be comparable to many synthetic medications, but with some dissimilarities in their fate and bioactivity after phase I and II metabolism. The overall bioavailability of PCs is determined mainly by chemical characteristics, bioaccessibility, and ADME. In this review, factors accounting for variation in PCs bioavailability are discussed because this information is crucial for validation of the health benefits of PCs and their mechanism of action. PMID:24336740

  15. Reading Every Single Day: A Journey to Authentic Reading

    ERIC Educational Resources Information Center

    Hudson, Alida K.; Williams, Joan A.

    2015-01-01

    This article details one teacher's implementation of reading workshop in her second grade classroom. She provided a framework for authentic reading using the five components of reading workshop: time, choice, response, community, and structure. She found that reading workshop is a highly effective practice for not only increasing students'…

  16. [From pirates to virus: the Oropesa's journey].

    PubMed

    Ledermann, Walter

    2014-04-01

    In 1902, being Chile a country free of yellow fever, the British steamship Oropesa arrived from Rio de Janeiro with three passengers suffering this disease. Captain Hayes rejected the quarantine imposed by the local Junta of Sanity in Punta Arenas and also in Coronel, following his journey with the sick passengers to Valparaiso, port where he accepted a brief quarantine and medical services for the most compromised of the three patients, who unfortunately died. The knowledge about yellow fever and the applicable epidemiological measures in that time in Chile come to us through the sessions of the Superior Council of Public Hygiene. The threat that implicated the presence of the Oropesa in Chilean coasts is compared with the arrival of British pirates and corsairs in the colonial centuries, before the independence, announced with the alarm cry charque (for Sharp) is coming to Coquimbo! PMID:24878913

  17. The evolutionary journey of Argonaute proteins

    PubMed Central

    Swarts, Daan C; Makarova, Kira; Wang, Yanli; Nakanishi, Kotaro; Ketting, René F; Koonin, Eugene V; Patel, Dinshaw J; van der Oost, John

    2015-01-01

    Argonaute proteins are conserved throughout all domains of life. Recently characterized prokaryotic Argonaute proteins (pAgos) participate in host defense by DNA interference, whereas eukaryotic Argonaute proteins (eAgos) control a wide range of processes by RNA interference. Here we review molecular mechanisms of guide and target binding by Argonaute proteins, and describe how the conformational changes induced by target binding lead to target cleavage. On the basis of structural comparisons and phylogenetic analyses of pAgos and eAgos, we reconstruct the evolutionary journey of the Argonaute proteins through the three domains of life and discuss how different structural features of pAgos and eAgos relate to their distinct physiological roles. PMID:25192263

  18. Alaska Simulator - A Journey to Planning

    NASA Astrophysics Data System (ADS)

    Weber, Barbara; Pinggera, Jakob; Zugal, Stefan; Wild, Werner

    The Alaska Simulator is an interactive software tool developed at the University of Innsbruck which allows people to test, analyze and improve their own planning behavior. In addition, the Alaska Simulator can be used for studying research questions in the context of software project management and other related fields. Thereby, the Alaska Simulator uses a journey as a metaphor for planning a software project. In the context of software project management the simulator can be used to compare traditional rather plan-driven project management methods with more agile approaches. Instead of pre-planning everything in advance agile approaches spread planning activities throughout the project and provide mechanisms for effectively dealing with uncertainty. The biggest challenge thereby is to find the right balance between pre-planning activities and keeping options open. The Alaska Simulator allows to explore how much planning is needed under different circumstances.

  19. A metaphysical journey in a comatose state.

    PubMed

    Gimenez, R

    1992-01-01

    This paper is about the intense experience of being in the hospital in a comatose state resulting from an aneurysm with a massive brain hemorrhage and two subsequent surgeries. The event begins with a premonition of what will happen from a street name. The experience of brain surgeries, along with the fine care of the nurses, left me with a truly memorable impression. This paper describes the various feelings and strong emotions that I experienced while in a comatose state. It suggests that a patient in a comatose state can exist in a deep state of emotions close to ecstasy. The paper concludes with gratefulness to all the people who followed me step by step on this journey. PMID:1286457

  20. Recovery from alcoholism: a spiritual journey.

    PubMed

    Bowden, J W

    1998-01-01

    The purpose of this study was to discover the internal aspects of change in persons who are doing well living without alcohol. The heuristic research method, a qualitative phenomenological design, was used to investigate the experience of recovery. Eight recovering alcoholics were interviewed in depth. The process of recovery reflected a mythological journey comprising a departure from the shadowland of drinking, initiation into the world of sobriety, and knowledge gained along the way. New adaptive strategies were acquired, including strengthening the will, training the mind, and exercising spiritual qualities in one's daily life. The profile of doing well in recovery also reflected self-acceptance and an ongoing search for connecting with the transpersonal realm. PMID:9782855

  1. Professional Associates: Journeys of Colleagues in Student Affairs

    ERIC Educational Resources Information Center

    Albin, Judith A.; Dungy, Gwendolyn Jordan

    2005-01-01

    This chapter reflects on the simultaneous journeys of two women, one a lesbian and one an ally. One woman is a midlevel manager in student affairs while the other is the executive director of a national association.

  2. In search of plutonium: A nonproliferation journey

    NASA Astrophysics Data System (ADS)

    Hecker, Siegfried

    2010-02-01

    In February 1992, I landed in the formerly secret city of Sarov, the Russian Los Alamos, followed a few days later by a visit to Snezhinsk, their Livermore. The briefings we received of the Russian nuclear weapons program and tours of their plutonium, reactor, explosives, and laser facilities were mind boggling considering the Soviet Union was dissolved only two months earlier. This visit began a 17-year, 41 journey relationship with the Russian nuclear complex dedicated to working with them in partnership to protect and safeguard their weapons and fissile materials, while addressing the plight of their scientists and engineers. In the process, we solved a forty-year disagreement about the plutonium-gallium phase diagram and began a series of fundamental plutonium science workshops that are now in their tenth year. At the Yonbyon reprocessing facility in January 2004, my North Korean hosts had hoped to convince me that they have a nuclear deterrent. When I expressed skepticism, they asked if I wanted to see their ``product.'' I asked if they meant the plutonium; they replied, ``Well, yes.'' Thus, I wound up holding 200 grams of North Korean plutonium (in a sealed glass jar) to make sure it was heavy and warm. So began the first of my six journeys to North Korea to provide technical input to the continuing North Korean nuclear puzzle. In Trombay and Kalpakkam a few years later I visited the Indian nuclear research centers to try to understand how India's ambitious plans for nuclear power expansion can be accomplished safely and securely. I will describe these and other attempts to deal with the nonproliferation legacy of the cold war and the new challenges ahead. )

  3. Memory modulates journey-dependent coding in the rat hippocampus

    PubMed Central

    Ferbinteanu, J.; Shirvalkar, P.; Shapiro, M. L.

    2011-01-01

    Neurons in the rat hippocampus signal current location by firing in restricted areas called place fields. During goal-directed tasks in mazes, place fields can also encode past and future positions through journey-dependent activity, which could guide hippocampus-dependent behavior and underlie other temporally extended memories, such as autobiographical recollections. The relevance of journey-dependent activity for hippocampal-dependent memory, however, is not well understood. To further investigate the relationship between hippocampal journey-dependent activity and memory we compared neural firing in rats performing two mnemonically distinct but behaviorally identical tasks in the plus maze: a hippocampus-dependent spatial navigation task, and a hippocampus-independent cue response task. While place, prospective, and retrospective coding reflected temporally extended behavioral episodes in both tasks, memory strategy altered coding differently before and after the choice point. Before the choice point, when discriminative selection of memory strategy was critical, a switch between the tasks elicited a change in a field’s coding category, so that a field that signaled current location in one task coded pending journeys in the other task. After the choice point, however, when memory strategy became irrelevant, the fields preserved coding categories across tasks, so that the same field consistently signaled either current location or the recent journeys. Additionally, on the start arm firing rates were affected at comparable levels by task and journey, while on the goal arm firing rates predominantly encoded journey. The data demonstrate a direct link between journey-dependent coding and memory, and suggest that episodes are encoded by both population and firing rate coding. PMID:21697365

  4. Journey to a Star Rich with Planets

    NASA Technical Reports Server (NTRS)

    2007-01-01

    [figure removed for brevity, see original site] Click on the image for movie of Journey to a Star Rich with Planets

    This artist's animation takes us on a journey to 55 Cancri, a star with a family of five known planets - the most planets discovered so far around a star besides our own.

    The animation begins on Earth, with a view of the night sky and 55 Cancri (flashing dot), located 41 light-years away in the constellation Cancer. It then zooms through our solar system, passing our asteroids and planets, until finally arriving at the outskirts of 55 Cancri.

    The first planet to appear is the farthest out from the star -- a giant planet, probably made of gas, with a mass four times that of Jupiter. This planet orbits its star every 14 years, similar to Jupiter's 11.9-year orbit.

    As the movie continues, the three inner planets are shown, the closest of which is about 10 to 13 times the mass of Earth with an orbital period of less than three days.

    Zooming out, the animation highlights the newest member of the 55 Cancri family - a massive planet, likely made of gas, water and rock, about 45 times the mass of Earth and orbiting the star every 260 days. This planet is the fourth out from the star, and lies in the system's habitable zone (green). A habitable zone is the place around a star where liquid water would persist. Though the newest planet probably has a thick gaseous envelope, astronomers speculate that it could have one or more moons. In our own solar system, moons are common, so it seems likely that they also orbit planets in other solar systems. If such moons do exist, and if they are as large as Mars or Earth, astronomers speculate that they would retain atmospheres and surface liquid water that might make interesting environments for the development of life.

    The animation ends with a comparison between 55 Cancri and our solar system.

    The colors of the illustrated planets were chosen to resemble those of our own solar

  5. Journeys in science: glycobiology and other paths.

    PubMed

    Dwek, Raymond A

    2014-01-01

    My scientific journeys began at Oxford nearly 50 years ago. My paths have taken me from magnetic resonance through enzyme systems to antibodies, which led directly to glycobiology. Oxford University's first industrial grant helped the development of the technology for isolating and sequencing oligosaccharides from glycoproteins. This technology was disseminated through a spin-off company, Oxford GlycoSystems, and by the establishment of the Glycobiology Institute. The technology gave rise to the concept of glycoforms, which allow diversification of a protein's properties. Iminosugars, which are glucosidase inhibitors, can interfere with the initial steps of glycan processing on proteins and inhibit three-dimensional folding of glycoproteins. Glucosidase targets for therapy include viral envelope glycoproteins. Clinical trials of an iminosugar as an antiviral for dengue virus are under way. Another iminosugar activity, inhibition of glycolipid synthesis, resulted in a drug for Gaucher disease, which was approved worldwide in 2002. The success of the company and the institute allowed me to undertake several initiatives, in the United Kingdom and abroad, that might help the paths of future generations of scientists. PMID:24437663

  6. Reflections on the journey: six short stories

    PubMed Central

    2011-01-01

    One of the goals of the 2011 International Year of Chemistry is to celebrate the contributions of women to science. A question that has been frequently asked in this regard is... Why is it necessary to highlight women in the "age of equality"? The reasons are varied but the facts are that many women scientists worked in obscurity throughout the 19th and even well into the 20th century, sometimes publishing anonymously to be heard. This celebration of Women in Science is one way to recognize both the resiliency and passion of these women. As part of this celebration, Chemistry Central Journal's Thematic Series of "Women in Chemistry" includes this article describing the path several women took as they pursued chemistry careers spanning the latter part of the 20th century and into the early 21st century. Sharon Haynie, Nancy Jones, Cheryl Martin, Paula Olsiewski, Mary Roberts and Amber Hinkle each have unique story of their personal journey from childhood to adulthood. As you read these stories, listen generously, and feel free to share your own stories, comments and thoughts. PMID:22059695

  7. On the Journey with the Dying: How General Practitioners Experience the Death of Their Patients

    ERIC Educational Resources Information Center

    Zambrano, Sofia C.; Barton, Christopher A.

    2011-01-01

    A grounded theory study was undertaken to understand how general practitioners (GPs) experience the death of their patients. Eleven GPs participated in semi-structured interviews. The participants explained their experience of a patient's death using the "death journey" metaphor. This journey, the Journey with the Dying, could be described from 5…

  8. Qualitative Research as a Hero's Journey: Six Archetypes to Draw on

    ERIC Educational Resources Information Center

    Villate, Vanessa M.

    2012-01-01

    Is the research process similar to a hero's journey? Just as a hero draws on different archetypes during the journey, a researcher moves through phases and must draw upon different strengths. In this article, the six archetypes that Pearson (1998) links to the hero's journey are described. Then, each phase of a qualitative research study is…

  9. A communication tool to improve the patient journey modeling process.

    PubMed

    Curry, Joanne; McGregor, Carolyn; Tracy, Sally

    2006-01-01

    Quality improvement is high on the agenda of Health Care Organisations (HCO) worldwide. Patient journey modeling is a relatively recent innovation in healthcare quality improvement that models the patient's movement through the HCO by viewing it from a patient centric perspective. Critical to the success of the redesigning care process is the involvement of all stakeholders and their commitment to actively participate in the process. Tools which promote this type of communication are a critical enabler that can significantly affect the overall process redesign outcomes. Such a tool must also be able to incorporate additional factors such as relevant policies and procedures, staff roles, system usage and measurements such as process time and cost. This paper presents a graphically based communication tool that can be used as part of the patient journey modeling process to promote stakeholder involvement, commitment and ownership as well highlighting the relationship of other relevant variables that contribute to the patient's journey. Examples of how the tool has been used and the framework employed are demonstrated via a midwife-led primary care case study. A key contribution of this research is the provision of a graphical communication framework that is simple to use, is easily understood by a diverse range of stakeholders and enables ready recognition of patient journey issues. Results include strong stakeholder buy-in and significant enhancement to the overall design of the future patient journey. Initial results indicate that the use of such a communication tool can improve the patient journey modeling process and the overall quality improvement outcomes. PMID:17945852

  10. The WIPP journey to waste receipt

    SciTech Connect

    Barnes, G.J.; Whatley, M.E.

    1997-04-01

    In the early 1970s the federal government selected an area in southeastern New Mexico containing large underground salt beds as potentially suitable for radioactive waste disposal. An extensive site characterization program was initiated by the federal government. This site became the Waste Isolation Pilot Plant, better known as WIPP. It is now 1997, over two decades after the initial selection of the New Mexico site as a potential radioactive waste repository. Numerous scientific studies, construction activities, and environmental compliance documents have been completed. The US Department of Energy (DOE) has addressed all relevant issues regarding the safety of WIPP and its ability to isolate radioactive waste from the accessible environment. Throughout the last two decades up to the present time, DOE has negotiated through a political, regulatory, and legal maze with regard to WIPP. New regulations have been issued, litigation initiated, and public involvement brought to the forefront of the DOE decision-making process. All of these factors combined to bring WIPP to its present status--at the final stages of working through the licensing requirements for receipt of transuranic (TRU) waste for disposal. Throughout its history, the DOE has stayed true to Congress` mandates regarding WIPP. Steps taken have been necessary to demonstrate to Congress, the State of New Mexico, and the public in general, that the nation`s first radioactive waste repository will be safe and environmentally sound. DOE`s compliance demonstrations are presently under consideration by the cognizant regulatory agencies and DOE is closer than ever to waste receipt. This paper explores the DOE`s journey towards implementing a permanent disposal solution for defense-related TRU waste, including major Congressional mandates and other factors that contributed to program changes regarding the WIPP project.

  11. Surprised by joy: a journey through suffering.

    PubMed

    Afeef, Majeda; Alkhoulli, Laila

    2010-01-01

    Understanding suffering as possible meaning of cancer for patients and their families is a necessary part of cancer nursing care. Suffering occurs when the intactness or integrity of the individuals is threatened or disrupted (Cassel 1999); the authors believe that exploring cancer patients' suffering is vital to improve patient quality care. This article discusses suffering as a feature for oncology patients at tertiary hospital in Jordan. We are aiming through understanding the three following narratives of cancer patients who experience and witness the suffer during their disease journey to illustrate how the suffering reflect their behavior and day to day life. The first case is a young man of 24 years old who was diagnosed with nasopharyngeal carcinoma five years ago, treated then relapsed and receiving palliative care up to moment, the narrative focus on his suffering from corrupted relations with his wife due to infected face wound and loss of the financial support. The Second case is a 38 years old female who diagnosed with melanoma 15 years ago, she experience psychological suffering due to changes in her body image. She is taking care of motor handicapped husband in addition to her Kids. The Last case is a 54 years old female who had lung cancer. She is still fighting her disease. Consequently, she is suffering from the disease, cause to affect her job.We found out that their spirituality and beliefs system enables them to endure and fight their disease, alleviate suffering, enhance adaptation and redefine hope. The health care team who provide the care for these cases focus interdisciplinary team approach who affirm that the transcendental is there when disease and mute or expressive suffering are recognized together, they do the work of creating a full meaning for patients and families. Nurses play a crucial role in managing such cases .It is the core of nursing care to presence the mean of listening, touching, acknowledging, honoring patient's wishes

  12. Cosmic Journeys: To the Edge of Gravity, Space, and Time ...

    NASA Technical Reports Server (NTRS)

    Wanjek, Christopher

    2000-01-01

    We are embarking upon a cosmic journey. From the safety of our home planet Earth, scientists plan to explore the very limits of the known Universe. Our travels will take us to where space and time cease to exist as we know them, and to where the secrets of the past and future lie captured in the starlight of the present across an expanse of billions of light-years. Cosmic Journeys, a new series of NASA space science missions, will take us to the limits of gravity, space, and time. This virtual journey will use the power of resolution far greater than what current telescopes can muster to transport us to the rim of a black hole, to eagle-eye views of the galaxies and voids that pervade the Universe, and to the earliest moments of time, just fractions of a second after the Big Bang. The goal of our Cosmic Journeys is to solve the mystery of gravity, a force that is all around us but cannot be seen.

  13. "The Road from Coorain": A Journey of Power.

    ERIC Educational Resources Information Center

    Madsen, Sandra

    "The Road from Coorain" is the autobiographical story of Jill Ker Conway, the first woman president of Smith College. The story traces Conway's journey from powerlessness to power. Born in the outback of Australia, where all people were powerless in the face of the vacillations of nature, forced off the land into a city life to which she was…

  14. Redemptive Journey: The Storytelling Motif in Andersen's "The Snow Queen."

    ERIC Educational Resources Information Center

    Misheff, Sue

    1989-01-01

    Discusses how Hans Christian Andersen's "The Snow Queen" uses the motif of storytelling to describe the journey taken by the heroine Gerda. Identifies a story as that which is alive and active and which causes catharsis for those who participate in it. (MG)

  15. A Journey through the Labyrinth of Mental Illness

    ERIC Educational Resources Information Center

    Cowan, Katherine C.

    2015-01-01

    Behind every student dealing with a mental health problem is a family trying to grasp what's happening to their child and struggling to do its best. This personal story shares the journey of a family as it confronts a child with Generalized Anxiety and Panic Disorder and describes the many starts and stops and confusion of diagnosing and…

  16. Perspectives on the Community College: A Journey of Discovery.

    ERIC Educational Resources Information Center

    Thomas, Noreen, Ed.

    This monograph was designed to provide a comprehensive and enlightened view of the community college as it faces complicated new demands. It offers articles written by community college professionals, including the following: (1) "A Journey of Discovery" by Albert L. Lorenzo; (2) "Organizational Readiness: Middle Age and the Middle Way" by Cindy…

  17. Antarctica: Scientific Journeys from McMurdo to the Pole.

    ERIC Educational Resources Information Center

    Brand, Judith, Ed.

    2002-01-01

    This issue of Exploratorium Magazine focuses on Antarctica. Antarctica has one of the most extreme climates in the world with an untouched environment inviting researchers with great opportunities for study. This issue describes the journey of four Exploratorium staff members to frozen Antarctica. Chapters include: (1) "Life at the Bottom of the…

  18. The E.P.I.C. Journey Sanctioning Model

    ERIC Educational Resources Information Center

    Fueglein, Jennifer S.; Price, Kevin S.; Alicea-Rodriguez, Adriana; McKinney, Jan Wilson; Jimenez, Anne L.

    2012-01-01

    As universities look for more effective ways to address violations of behavioral standards, a proposed solution is to infuse intentional development into well-established conduct processes inherently focused on legal mandates and due process. The E.P.I.C. Journey Sanctioning Model was designed to refocus the outcomes of the conduct process to…

  19. "Creation's Journey": Excerpts from the Inaugural Exhibition and Book.

    ERIC Educational Resources Information Center

    Hill, Tom, Hill, Richard W., Sr., Ed.

    1994-01-01

    Contains excerpts from the companion book to the inaugural exhibition "Creation's Journey: Masterworks of Native American Identity and Belief" at the George Gustav Heye Center of the National Museum of the American Indian in New York City. Describes the cultural traditions behind some of the 165 objects chosen for their artistic achievement,…

  20. ABCs of Being Smart: J Is for Journey

    ERIC Educational Resources Information Center

    Foster, Joanne

    2013-01-01

    The old saying, "life is a journey" may sound cliched, but the words are nevertheless true. Children can learn a great deal from the travels and directions chosen by others, and especially from people whose life stories or experiences offer inspiration by virtue of their effort, perseverance, and acquired success. This article presents a…

  1. Journey Home: A Multimedia Work in Progress on Homer's Odyssey.

    ERIC Educational Resources Information Center

    Stalker, Sandy; Whitney, Terri

    In 1992, North Shore Community College received a grant to develop a multimedia program for literature instruction based on Homer's "Odyssey." Rather than providing the text of the work, the program, "Journey Home," provides access to a wide array of related materials related to the "Odyssey," including 150 excerpts from critical essays, articles,…

  2. The Dudley Challenges: Virtual Balloon Journeys and Real Learning

    ERIC Educational Resources Information Center

    Hackett, Shirley; Davies, John; Tibble, Eric

    2005-01-01

    The Dudley Challenges were developed to celebrate the millennium and the first year of the Dudley Grid for Learning. Three Challenges, Challenge 2000 the original resource, Challenge Europa and Junior Trek, are based on virtual balloon journeys, visiting a series of interesting cultural centres. Access to each centre visited is by solving a series…

  3. Instructional Design Practice as Innovative Learning: Journeys into the Unfamiliar

    ERIC Educational Resources Information Center

    Yanchar, Stephen C.

    2016-01-01

    Critical discussions within the field of instructional design have addressed the roles and competencies of designers, as well as the nature of design work per se. This article presents an overarching metaphor--namely, instructional design as a journey into the unfamiliar--that views design as a two-fold learning enterprise (i.e., innovative and…

  4. Missing Links: A Serendipitous Journey into Teaching Styles.

    ERIC Educational Resources Information Center

    Worfel, Paul

    This paper documents the journey of a researcher into the teacher effectiveness movement and efforts to find missing links to show the correlations between teacher behavior and student learning. The paper also considers how the forces within education tend to consume embryonic ideas in teacher education, rather than nurture them in an effort to…

  5. Prehistoric Journey: Denver Museum of Natural History Educators' Sourcebook.

    ERIC Educational Resources Information Center

    Smith, Rebecca L.; Leigh, Vicki; Crew, Diana Lee

    This sourcebook prepares students for a visit to the "Prehistoric Journey" exhibit at the Denver Museum of Natural History. The exhibit opened October 23, 1995, and offered a dramatic exploration of 3.5 billion years of life on Earth. Dioramas and "enviroramas" depict seven critical points in life's history. In addition to the chronological…

  6. The Spiritual Journey: Black Female Adult Learners in Higher Education

    ERIC Educational Resources Information Center

    Jones Tinner, LaShanta Y.

    2013-01-01

    This study explored the experience of Black female adult learners and how spirituality influenced their academic journeys. Research concerning Black female adult learners in higher education is ostensibly partial. These data offered an extended understanding of Black female adult learners' academic experiences, while also investigating common…

  7. Heuristic Inquiry: A Personal Journey of Acculturation and Identity Reconstruction

    ERIC Educational Resources Information Center

    Djuraskovic, Ivana; Arthur, Nancy

    2010-01-01

    Heuristic methodology attempts to discover the nature and meaning of phenomenon through internal self-search, exploration, and discovery. Heuristic methodology encourages the researcher to explore and pursue the creative journey that begins inside one's being and ultimately uncovers its direction and meaning through internal discovery (Douglass &…

  8. A Narrative Analysis of a Teacher Educator's Professional Learning Journey

    ERIC Educational Resources Information Center

    Vanassche, Eline; Kelchtermans, Geert

    2016-01-01

    This article reports on a narrative analysis of one teacher educator's learning journey in a two-year professional development project. Professional development is conceived of as the complex learning processes resulting from the meaningful interactions between the individual teacher educator and his/her working context. Our analysis indicates…

  9. What Will I Be? Journey to Your Dreams.

    ERIC Educational Resources Information Center

    Minnesota Higher Education Services Office, 2004

    2004-01-01

    This publication provides, at an early age, students and parents of low income or no previous post-secondary education with the information, skills, and experiences that will help encourage and prepare them to complete high school and pursue post-secondary education. Sections include: Your Career Journey; Your Circle of Support; What Makes Me…

  10. Journeys. Windows on Social Studies: Multicultural Adventures through Literature.

    ERIC Educational Resources Information Center

    Westley, Joan; Melton, Holly

    This resource book is one of a series containing lesson plans for grades 1-3 designed to support children's literature books sharing familiar social studies themes. "Journeys" presents eight different children's books related to the theme. For each book social studies concepts are presented, followed by four activities called "windows." Some of…

  11. Literacy on the Move: A Journal for the Journey

    ERIC Educational Resources Information Center

    Curtis, Laurie J.

    2013-01-01

    Travel provides students with multiple opportunities to learn about people, places, and the world around them. At times, students are given opportunities to travel causing them to be absent from the classroom. This manuscript provides a practical suggestion for engaging students in learning while on the journey. Students are asked to share and…

  12. Immigrant and Refugee Youth: Migration Journeys and Cultural Values

    ERIC Educational Resources Information Center

    Fong, Rowena

    2007-01-01

    Professionals working with immigrant and refugee youth in schools, mental health clinics, hospitals, and adolescent-serving organizations are better equipped to offer culturally appropriate interventions and prevention strategies if they understand their clients' migration journeys and legal status. Professionals who understand the cultural…

  13. The Public Health Journey: The Meaning and the Moment

    ERIC Educational Resources Information Center

    Koh, Howard K.

    2013-01-01

    The public health journey is a remarkable one, filled with twists and turns as well as risks and rewards. Because promoting the health of others represents a mission brimming with meaning, our professional work is also profoundly personal. At this extraordinary moment in our nation's public health history, I reflect on the purpose of the…

  14. Silent Partners: Actor and Audience in Geese Theatre's "Journey Woman"

    ERIC Educational Resources Information Center

    Bottoms, Stephen

    2010-01-01

    This essay considers the performance context and aesthetics of "Journey Woman", a play devised to initiate a week-long rehabilitative groupwork programme for female prisoners. Although Geese Theatre UK are one of the country's longest-established companies specialising in drama work within the criminal justice sector, this 2006 piece is their…

  15. Reflect, Reconsider, Reposition: Finding Self in the Journey of Others.

    ERIC Educational Resources Information Center

    Mok, Angel

    2012-01-01

    Autoethnography is adopted as the procedure and orientation for this PhD study which aims to explore the cultural identity of the Chinese families and its influences on their children's mathematics learning. The purpose of this paper is two-fold. First, readers are invited to travel with the researcher a journey in which she explores her…

  16. Journey Through the Universe: Tenth Anniversary in 2014!

    NASA Astrophysics Data System (ADS)

    Harvey, J.

    2014-07-01

    Hawaii will celebrate its tenth anniversary of the flagship Journey through the Universe program that began in 2004. The Gemini-led initiative has engaged hundreds of astronomers and astronomy educators that have visited over 2,700 classrooms, visiting over 60,000 students over the course of the last nine years. The scientists have brought excitement and inspiration about the life-long possibilities available in science, technology and mathematics to our students. The Journey program nurtures our students' innate curiosity, offers workshops for hundreds of teachers in Science, Technology, Engineering, and Math (STEM) education, and provides an opportunity for our community members to visit the classrooms alongside our astronomers. This ten-day annual event also includes Family Science Events that are enjoyed by thousands. For the 2013 program, our governor, Neil Abercrombie, inquired about the program and its enormous impact on Hawaii's students. Governor Abercrombie actively participated by visiting classrooms at different schools and attending our chamber of commerce appreciation event. This paper will share how the Journey program came to be and what is anticipated for the tenth anniversary. Journey through the Universe is a model outreach initiative that could be duplicated in other locations.

  17. Take a Walk with Me: A Journey of Positive Change

    ERIC Educational Resources Information Center

    Reeble, Tina; Watts, Charlotte; Axtell, Paul; Carnes, Kevin; Barth, Heinrich; Barth, Irene

    2011-01-01

    When "Exchange" magazine selected Jewel's Learning Center in Houston to be the recipient of the "Exchange" Center Makeover, a journey of change and discovery began. With the help of many collaborative partners, Jewel's director Charlotte Watts and her family were able to bring new indoor and outdoor spaces to children and teachers affected by…

  18. Exploration of Praxis through Personal and Professional Journey: Implications

    ERIC Educational Resources Information Center

    Singh, Navin Kumar

    2012-01-01

    This paper explores the meaning of praxis through the personal and professional journey of the author, emphasizing the thoughts of major proponents of praxis and their contributions in the field. What emerges through this exploration is that praxis is not knowing but putting the knowing into action for the betterment of all humankind through…

  19. Historical Conflict and Incitement Also Provoke the Journey to Terrorism

    ERIC Educational Resources Information Center

    Steiner, Joseph

    2005-01-01

    This paper presents comments on F. M. Moghaddam's article, (see record 2005-01817-002) which uses the metaphor of a narrowing staircase "to provide a more in-depth understanding of terrorism", describes the journey as being provoked by how people perceive of levels of fairness and experience feelings of relative deprivation. If the masses perceive…

  20. From Skeptic to Believer: One Teacher's Journey Implementing Literature Circles

    ERIC Educational Resources Information Center

    Day, Deanna; Ainley, Glenna

    2008-01-01

    This is the story of one middle school teacher's journey of implementing literature circles with English language learners. Theory and research suggest that literature circles are valuable and important for young adolescents yet many teachers are still skeptical about implementing them. During this three-month study 22 sixth graders, 12 of them…

  1. Global health and neonatal nursing: a personal journey.

    PubMed

    Kenner, Carole; Boykova, Marina

    2012-09-01

    The need for improvement of neonatal nursing care is a global issue. Neonatal nurses have an important role in optimizing these health outcomes for neonates and their families. This article describes the personal journey of one nurse and her mentee. It describes how a passion for neonates led to global policy work. PMID:22895204

  2. "The Matrix": An Allegory of the Psychoanalytic Journey

    ERIC Educational Resources Information Center

    Mischoulon, David; Beresin, Eugene V.

    2004-01-01

    Objective: "The Matrix" has been a huge commercial and critical success and has spawned a series of books and essays exploring the philosophical and religious themes in the story. Methods: The authors propose that "The Matrix" can be interpreted as an allegory for an individual's journey into spiritual and mental health, achieved by overcoming…

  3. A Hero's Journey: Young Women among Males in Forestry Education.

    ERIC Educational Resources Information Center

    Follo, Gro

    2002-01-01

    Norwegian girls' experiences in secondary school forestry courses were analyzed in terms of the "hero's journey" archetypal myth. Interviews with 12 girls and 11 boys in forestry courses indicated that girls were capable and fit for practical forestry work, gender attitudes were not a barrier, and girls did not meet opposition from male students…

  4. Five for Sydney--A Journey through Science

    ERIC Educational Resources Information Center

    Lam, Stephen

    2014-01-01

    What is science? Depending on who is asked, it may mean the pursuit of knowledge, explanations of the everyday world, a difficult subject at school, or a field populated by larger than life characters such as Einstein, Feynman, or Hawking. For the author, science has been and remains an unexpected journey, an adventure and an ever-changing career.…

  5. A Journey Backwards: History through Style in Children's Fiction

    ERIC Educational Resources Information Center

    Ringrose, Christopher

    2007-01-01

    A & C Black's "Flashbacks" series invites its readers to "Read a "Flashback"..take a journey backwards in time". There are several ways in which children's fiction has encouraged its readers to engage with and care about history: through the presence of ghosts, through frame stories, time travel, or simply setting the narrative in the past.…

  6. "The Moon Village and Journey to Mars enable each other"

    NASA Astrophysics Data System (ADS)

    Beldavs, Vidvuds

    2016-07-01

    NASA has proposed the Journey to Mars, a multi-decade collaborative international effort to establish permanent manned operations on the Martian surface as well as in orbit, most likely on the Martian moons. NASA's proposed the Journey to Mars has come under politically motivated attack as illusory, as beyond NASA's capabilities and anticipated NASA budgets in the foreseeable future. [1]. Other concerns come from various communities of researchers concerned about securing sustaining funding for their largely robotic research missions. ESA's Director General Dietrich Woerner's proposed Moon Village faces challenges ESA member states concerned about sustaining funding for projects already underway or in planning. Both the Journey to Mars and Moon Village raise the question - who will or who can pay for it? The 2013 US Research Council study suggested potential benefits to a mission to Mars from activities on the Moon [2]. The NASA funded Flexible Lunar Architecture study came to similar conclusions using a different methodology [3]. A logistics analysis by an MIT team suggested the possibility of cost savings through use of lunar water for propellant to reach Mars [4]. The highly promising private-public financing approach has been examined for potential application to funding the costs of reaching Mars [5]. Insofar as the feasibility of utilization of lunar water has not been determined these conclusions are speculative. This study will examine the following alternative scenarios for establishing sustainable, manned operations on Mars and permanent manned operations on the Moon: A. NASA-led Journey to Mars without an ESA-led Moon Village B. ESA-led Moon Village without NASA-led Journey to Mars C. NASA-led Journey to Mars with an ESA-led Moon Village D. Shared Infrastructure scenario - NASA-led Journey to Mars with ESA-led Moon Village and with a potential JAXA-led space-based-solar power initiative E. Space Industrialization scenario - Shared Infrastructure scenario

  7. The Unknown/The Unanticipated: A Surgical Journey of Correcting HIV-Related Abdominal Lipodystrophy.

    PubMed

    Vella, Michele M

    2016-03-01

    The aim of this study was to explore the pre- and postsurgical journey to correct severe abdominal lipodystrophy of a woman living as AIDS defined for over 23 years. It utilized interpretative phenomenological analysis (IPA) and a single-case-study approach to capture the subjective understanding and sense-making of this surgical process. Verbatim transcripts of seven semi-structured interviews, three participant-created word boards of words or phrases clipped from magazines, field notes, and a reflexive journal were collected as data. Analysis revealed two superordinate themes: the unknown and the unanticipated. These themes simultaneously manifest with shared and nuanced meanings, including the unknown and unanticipated of surviving AIDS and discovering lipodystrophy, the unknown and the unanticipated of the surgical intervention itself, and finally the unknown and the unanticipated of postsurgical complications and experiences within outpatient and inpatient medical settings. PMID:25670663

  8. The covered wagon journey: student chronicles in advanced holistic nursing.

    PubMed

    Purnell, Marguerite J; Lange, Bernadette; Bailey, Christie; Drozdowicz, Aleida; Eckes, Shirley; Kinchen, Elizabeth; Smith-Atkinson, Nikkisha

    2013-01-01

    This article recounts the experiences of a first cohort of graduate students in a newly implemented advanced holistic nursing (AHN) track, one of only a handful in the nation, and the first in Florida. The increasing popularity of complementary and alternative healing processes represents the insufficiency of a health system of fragmented care and a desire for holistic healing that is beyond mainstream allopathic care. Graduate holistic nurse education equips nurses to explore the commitment needed to advance the evolution of health care. The covered wagon journey is a metaphor for this meaningful participation. Students journaled their experiences as cotravelers in a lone wagon: embarking on a courageous journey, forging a path of discovery, and reaching their destination as pioneers. This cohort experience embodied the central tenets of holistic nursing, thus creating conscious change and unity within a learning community. The future of AHN is addressed in the context of the contemporary health care environment. PMID:23600022

  9. Early failure with the Journey-Deuce bicompartmental knee arthroplasty.

    PubMed

    Dudhniwala, A G; Rath, N K; Joshy, S; Forster, M C; White, S P

    2016-07-01

    The aim of this study was to evaluate the early functional outcome and survivorship of a bicompartmental knee arthroplasty implant (Journey-Deuce) in a cohort of patients with combined medial and patellofemoral degenerative osteoarthritis. Fifteen patients with a mean age of 57 years were followed up prospectively and evaluated with clinical examination, Oxford knee score and radiology imaging. Poor pain scores, concerns about the tibial fixation, early aseptic loosening of the tibial component and a revision rate of 60 % at a minimum follow-up of 54 months are reported. Implantation of this prosthesis was stopped at our institution well before the first revision due to an unfavourable early clinical response. This was further endorsed by an unacceptable revision rate. The outcome of the Journey-Deuce bicompartmental knee replacement was considerably worse than the published outcome of total knee replacement. PMID:27001223

  10. The Pathway to Excellence Experience: One Psychiatric Hospital's Journey.

    PubMed

    Mahoney, Jane S; Jackson, Jennifer M; Palyo, Nancy

    2016-01-01

    Psychiatric nurse executives and managers face an ongoing challenge to create positive professional work environments that support the recruitment and retention of the best nurses. The Pathway to Excellence program is an organizational credentialing program that designates a hospital as a workplace of choice for nursing. This article describes one psychiatric hospital's journey to become and maintain a Pathway to Excellence designation in the midst of transition. Challenges faced and novel approaches used, along the journey, are shared. The use of Appreciative Inquiry techniques has led to positive changes and heightened energy among nurses. Our experiences suggest that effective shared governance is central to a hospital's Pathway to Excellence success. We attribute the steady increase in the retention rate of nurses, in large part, to the Pathway to Excellence program. PMID:27259129

  11. Continuing Caritas Journey-Reflections Upon a Shared Private Pilgrimage.

    PubMed

    Watson, Jean

    2014-09-01

    This manuscript is a continuing saga of an earlier walking pilgrimage (El Camino in northern Spain): now a journey to Nepal, Bhutan, and Tibet, this time with others instead of alone. As I journeyed in close company with five others we experienced and expressed surprises about our selves and each other-our shared vulnerability, tolerance, and humility-uncovering lessons in living Caritas. As I trekked through these inner and outer adventures, Bhutan was discovered as a light of hope-a living metaphor of a people and a culture that hold and practice Caritas principles of loving-kindness, compassion, and equanimity for all sentient beings. Bhutan, a small country bordered by China and India, the only country in the world with a gross national happiness index and shared Caritas consciousness of oneness and connectedness of all, serves as a sacred path for humanity-a geographic Bodhisattva. PMID:25081366

  12. The Personal Narrative of a Nurse: A Journey Through Practice.

    PubMed

    Edwards, Sharon L

    2016-06-01

    This article examines my phases of holistic learning concerning how I became a nurse, using story presented in a personal narrative style. I have incorporated my own stories to elaborate my journey. First, my early life in the East End of London and how this influenced my becoming a nurse. Second, I give an account of my journey through practice, where I examine how I developed my own learning from professional practice, drawing on some personal illustrations presented as stories. I have set out to explore how my stories of practice have influenced my progress, and I present a personal account of such learning in general from the lens of a nurse educator. PMID:26025093

  13. Felicia's journey: an object-relational study of psychopathy.

    PubMed

    Zlotnick-Woldenberg, C

    2001-01-01

    This paper examines Atom Egoyan's film, Felicia's Journey, based on the novel of the same name by William Trevor, from an object-relational viewpoint. The protagonist's characteristic defense mechanisms of splitting, projection, and denial, which are characteristic of the schizoid position, are explored in depth, as are the antecedents of this behavior, as seen in his early relationship with his mother. Finally, the relationship between his psychopathy and his functioning in the schizoid position is considered. PMID:11291190

  14. In Search of "Best Practice": A Professional Journey

    ERIC Educational Resources Information Center

    Martin, Karen

    2012-01-01

    In this article, the author tells her professional journey as an educator of students who are deaf and hard of hearing. The author started her career in 1991, fresh out of college with her bachelor's degree in education of the deaf K-12. She took a job at the Delaware School for the Deaf (DSD) as a resident advisor in the dorm program. Here she is…

  15. A Journey into the Active Center of Nitrogenase

    PubMed Central

    Hu, Yilin; Ribbe, Markus W.

    2014-01-01

    Nitrogenase catalyzes the reduction of N2 to NH3, a key step in the global nitrogen cycle. This article describes our journey toward the definition of a complete molecular structure of the active site of nitrogenase, with an emphasis on the discovery of the interstitial carbide and the radical SAM-dependent insertion of this atom into the active FeMo cofactor site of nitrogenase. PMID:24752864

  16. Cosmic Journeys: To the Edge of Gravity, Space and Time...

    NASA Technical Reports Server (NTRS)

    Wanjek, Christopher

    2000-01-01

    A star explodes, blowing its contents into interstellar space. At its core, a black hole may form. Or maybe a neutron star or white dwarf, depending on the size of the original star. Over the next million years, a new star may form from the left over gas. The ever-changing Universe is the ultimate recycler. NASA's Cosmic Journeys is a set of missions that will of explore the Universe's many mysteries. An summary of future missions is presented.

  17. Communication Partners' Journey through Their Partner's Hearing Impairment

    PubMed Central

    Manchaiah, Vinaya K. C.; Stephens, Dafydd; Lunner, Thomas

    2013-01-01

    The objective of this study was to further develop the Ida Institute model on communication partners' (CPs) journey through experiences of person with hearing impairment (PHI), based on the perspectives of CPs. Nine CPs of hearing aid users participated in this study, recruited through the Swansea hearing impaired support group. Semi-structured interviews were conducted, the data were analysed using qualitative thematic analysis and presented with the use of process mapping approach. Seven main phases were identified in the CP journey which includes: (1) contemplation, (2) awareness, (3) persuasion, (4) validation, (5) rehabilitation, (6) adaptation, and (7) resolution. The Ida Institute model (based on professionals' perspective) was compared with the new template developed (based on CPs' perspectives). The results suggest some commonalities and differences between the views of professionals and CPs. A new phase, adaptation, was identified from CPs reported experiences, which was not identified by professionals in the Ida Institute model. The CP's journey model could be a useful tool during audiological enablement/rehabilitation sessions to promote discussion between the PHI and the CP. In addition, it can be used in the training of hearing healthcare professionals. PMID:23533422

  18. Motivating student learning using a formative assessment journey.

    PubMed

    Evans, Darrell J R; Zeun, Paul; Stanier, Robert A

    2014-03-01

    Providing formative assessment opportunities has been recognised as a significant benefit to student learning. The outcome of any formative assessment should be one that ultimately helps improve student learning through familiarising students with the levels of learning required, informing them about gaps in their learning and providing feedback to guide the direction of learning. This article provides an example of how formative assessments can be developed into a formative assessment journey where a number of different assessments can be offered to students during the course of a module of teaching, thus utilising a spaced-education approach. As well as incorporating the specific drivers of formative assessment, we demonstrate how approaches deemed to be stimulating, interactive and entertaining with the aim of maximising enthusiasm and engagement can be incorporated. We provide an example of a mixed approach to evaluating elements of the assessment journey that focuses student reaction, appraisal of qualitative and quantitative feedback from student questionnaires, focus group analysis and teacher observations. Whilst it is not possible to determine a quantifiable effect of the assessment journey on student learning, usage data and student feedback shows that formative assessment can achieve high engagement and positive response to different assessments. Those assessments incorporating an active learning element and a quiz-based approach appear to be particularly popular. A spaced-education format encourages a building block approach to learning that is continuous in nature rather than focussed on an intense period of study prior to summative examinations. PMID:24111930

  19. Motivating student learning using a formative assessment journey

    PubMed Central

    Evans, Darrell J R; Zeun, Paul; Stanier, Robert A

    2014-01-01

    Providing formative assessment opportunities has been recognised as a significant benefit to student learning. The outcome of any formative assessment should be one that ultimately helps improve student learning through familiarising students with the levels of learning required, informing them about gaps in their learning and providing feedback to guide the direction of learning. This article provides an example of how formative assessments can be developed into a formative assessment journey where a number of different assessments can be offered to students during the course of a module of teaching, thus utilising a spaced-education approach. As well as incorporating the specific drivers of formative assessment, we demonstrate how approaches deemed to be stimulating, interactive and entertaining with the aim of maximising enthusiasm and engagement can be incorporated. We provide an example of a mixed approach to evaluating elements of the assessment journey that focuses student reaction, appraisal of qualitative and quantitative feedback from student questionnaires, focus group analysis and teacher observations. Whilst it is not possible to determine a quantifiable effect of the assessment journey on student learning, usage data and student feedback shows that formative assessment can achieve high engagement and positive response to different assessments. Those assessments incorporating an active learning element and a quiz-based approach appear to be particularly popular. A spaced-education format encourages a building block approach to learning that is continuous in nature rather than focussed on an intense period of study prior to summative examinations. PMID:24111930

  20. Community and inquiry: journey of a science teacher

    NASA Astrophysics Data System (ADS)

    Goldberg, Jennifer; Welsh, Kate Muir

    2009-09-01

    In this case study, we examine a teacher's journey, including reflections on teaching science, everyday classroom interaction, and their intertwined relationship. The teacher's reflections include an awareness of being "a White middle-class born and raised teacher teaching other peoples' children." This awareness was enacted in the science classroom and emerges through approaches to inquiry . Our interest in Ms. Cook's journey grew out of discussions, including both informal and semi-structured interviews, in two research projects over a three-year period. Our interest was further piqued as we analyzed videotaped classroom interaction during science lessons and discovered connections between Ms. Cook's reflections and classroom interaction. In this article, we illustrate ways that her journey emerges as a conscientization. This, at least in part, shapes classroom interaction, which then again shapes her conscientization in a recursive, dynamic relationship. We examine her reflections on her "hegemonic (cultural and socio-economic) practices" and consider how these reflections help her reconsider such practices through analysis of classroom interaction. Analyses lead us to considering the importance of inquiry within this classroom community.

  1. A journey toward wholeness, a journey to God: physical fitness as embodied spirituality.

    PubMed

    Greenwood, Tracey C; Delgado, Teresa

    2013-09-01

    Physical fitness expressed through exercise can be, if done with the right intention, a form of spiritual discipline that reflects the relational love of humanity to God as well as an expression of a healthy love of the embodied self. Through an analysis of the physiological benefits of exercise science applied to the human body, this paper will demonstrate how such attention to the optimal physical fitness of the body, including weight and cardiovascular training and nutrition, is an affirmation of three foundational theological principles of human embodiment: as created in the "imago Dei", as unified body/spirit, and as part of God's creation calling for proper stewardship. In a contemporary climate where women's bodies in particular are viewed through the lens of commodification-as visual objects for sale based on prescribed notions of superficial esthetics and beauty-as well as the consistently high rates of eating disorders such as anorexia, bulimia, and obesity, authors Greenwood and Delgado offer a vision of how women and men can imagine a subjective relationship with their own bodies that reflects the abundant love of God for God's creation. Spoken from the lived experience of professional fitness competitor and trainer, as well as trained biokineticist, Dr. Greenwood presents the most current scientific data in the field of biokinetics that grounds the theological analysis offered by Dr. Delgado, whose personal journey through anorexia and scholarly emphasis on Christian theological anthropology inform this work. Taken together, Greenwood and Delgado suggest a response to God's love for humanity, including our physical bodily humanity, which entails a responsibility to attend to the physical fitness of our bodies in order to live into the fullness, flourishing and love of God's creation as God intended. PMID:22005967

  2. Nanopores: A journey towards DNA sequencing

    PubMed Central

    Wanunu, Meni

    2013-01-01

    Much more than ever, nucleic acids are recognized as key building blocks in many of life's processes, and the science of studying these molecular wonders at the single-molecule level is thriving. A new method of doing so has been introduced in the mid 1990's. This method is exceedingly simple: a nanoscale pore that spans across an impermeable thin membrane is placed between two chambers that contain an electrolyte, and voltage is applied across the membrane using two electrodes. These conditions lead to a steady stream of ion flow across the pore. Nucleic acid molecules in solution can be driven through the pore, and structural features of the biomolecules are observed as measurable changes in the trans-membrane ion current. In essence, a nanopore is a high-throughput ion microscope and a single-molecule force apparatus. Nanopores are taking center stage as a tool that promises to read a DNA sequence, and this promise has resulted in overwhelming academic, industrial, and national interest. Regardless of the fate of future nanopore applications, in the process of this 16-year-long exploration, many studies have validated the indispensability of nanopores in the toolkit of single-molecule biophysics. This review surveys past and current studies related to nucleic acid biophysics, and will hopefully provoke a discussion of immediate and future prospects for the field. PMID:22658507

  3. The Evaluation of the Cultural Journeys in the Information Society Environment as an Educational Aid

    ERIC Educational Resources Information Center

    Fakas, Georgious John; Lamprianou, Iasonas; Andreou, Andreas; Pampaka, Maria; Schizas, Christos

    2005-01-01

    The "Cultural Journeys in the Information Society" is a dynamic hypermedia environment, which proposes the "Electronic Roads" as a meta-form for exploring cultural information that can form "Cultural Journeys." The Electronic Roads meta-form facilitates travelers to explore the information space in a natural and continuous way similar to the…

  4. STAR: An Adult Education Teacher's Journey with Evidence-Based Reading Instruction

    ERIC Educational Resources Information Center

    Robertson, Lisa

    2007-01-01

    In this article, the author shares her journey with evidence-based reading instruction. Her experience with evidence-based reading instruction (as the adult basic education coordinator at Windham Adult Education in Windham, Maine) has been a journey of change both professionally and programmatically, and the students at Windham Adult Education are…

  5. Establishing Research Universities in Ukrainian Higher Education: The Incomplete Journey of a Structural Reform

    ERIC Educational Resources Information Center

    Hladchenko, Myroslava; de Boer, Harry F.; Westerheijden, Don F.

    2016-01-01

    The idea of the research university as a key institution for social and economic development in knowledge-intensive societies has been adopted by the Ukrainian government after the fall of the communist regime. Establishing research universities is a long journey during which many things might happen. To understand this journey better in the case…

  6. The Road Less Travelled: The Journey of Immersion into the Virtual Field

    ERIC Educational Resources Information Center

    Fitzsimons, Sabrina

    2013-01-01

    This article provides an account of my experience of immersion as a third-level teacher into the three-dimensional multi-user virtual world Second Life for research purposes. An ethnographic methodology was employed. Three stages in this journey are identified: separation, transition and transformation. In presenting this journey of immersion, it…

  7. The Journey: A Handbook for Parents of Children Who are Gifted and Talented

    ERIC Educational Resources Information Center

    Online Submission, 2004

    2004-01-01

    The journey for children who are gifted and talented can be exciting and challenging. There are so many twists and turns, detours, and confusing signs that many parents feel they need some sort of road map to guide their children on this journey. Because each child is different, there is no one road map to follow. What this handbook can offer…

  8. A Torrent of Change: Enhancing Effective Change in Special Education--One School's Journey

    ERIC Educational Resources Information Center

    Morris, Chris; Katon, Shirley

    2006-01-01

    This article is the story of a school's journey from a deficit model of special education needs programming to an inclusive model of student learning support. The heart of this journey was the identification and management of tensions and complexities surrounding educational beliefs, school values, and pedagogical practices. This article will…

  9. Multi-dimensional knowledge translation: enabling health informatics capacity audits using patient journey models.

    PubMed

    Catley, Christina; McGregor, Carolyn; Percival, Jennifer; Curry, Joanne; James, Andrew

    2008-01-01

    This paper presents a multi-dimensional approach to knowledge translation, enabling results obtained from a survey evaluating the uptake of Information Technology within Neonatal Intensive Care Units to be translated into knowledge, in the form of health informatics capacity audits. Survey data, having multiple roles, patient care scenarios, levels, and hospitals, is translated using a structured data modeling approach, into patient journey models. The data model is defined such that users can develop queries to generate patient journey models based on a pre-defined Patient Journey Model architecture (PaJMa). PaJMa models are then analyzed to build capacity audits. Capacity audits offer a sophisticated view of health informatics usage, providing not only details of what IT solutions a hospital utilizes, but also answering the questions: when, how and why, by determining when the IT solutions are integrated into the patient journey, how they support the patient information flow, and why they improve the patient journey. PMID:19162956

  10. Journey to vaccination: a protocol for a multinational qualitative study

    PubMed Central

    Wheelock, Ana; Miraldo, Marisa; Parand, Anam; Vincent, Charles; Sevdalis, Nick

    2014-01-01

    Introduction In the past two decades, childhood vaccination coverage has increased dramatically, averting an estimated 2–3 million deaths per year. Adult vaccination coverage, however, remains inconsistently recorded and substandard. Although structural barriers are known to limit coverage, social and psychological factors can also affect vaccine uptake. Previous qualitative studies have explored beliefs, attitudes and preferences associated with seasonal influenza (flu) vaccination uptake, yet little research has investigated how participants’ context and experiences influence their vaccination decision-making process over time. This paper aims to provide a detailed account of a mixed methods approach designed to understand the wider constellation of social and psychological factors likely to influence adult vaccination decisions, as well as the context in which these decisions take place, in the USA, the UK, France, India, China and Brazil. Methods and analysis We employ a combination of qualitative interviewing approaches to reach a comprehensive understanding of the factors influencing vaccination decisions, specifically seasonal flu and tetanus. To elicit these factors, we developed the journey to vaccination, a new qualitative approach anchored on the heuristics and biases tradition and the customer journey mapping approach. A purposive sampling strategy is used to select participants who represent a range of key sociodemographic characteristics. Thematic analysis will be used to analyse the data. Typical journeys to vaccination will be proposed. Ethics and dissemination Vaccination uptake is significantly influenced by social and psychological factors, some of which are under-reported and poorly understood. This research will provide a deeper understanding of the barriers and drivers to adult vaccination. Our findings will be published in relevant peer-reviewed journals and presented at academic conferences. They will also be presented as practical

  11. Experiences and perspectives on the GIST patient journey

    PubMed Central

    Macdonald, Nancy; Shapiro, Ari; Bender, Christina; Paolantonio, Marc; Coombs, John

    2012-01-01

    Purpose The tyrosine kinase inhibitor (TKI) imatinib has improved outcomes for patients with unresectable or metastatic gastrointestinal stromal tumors (GIST), and for patients receiving adjuvant therapy following GIST resection. This qualitative study explored the experiences and emotions of patients through GIST diagnosis, treatment initiation, disease control, and in some patients, loss of response and therapy switch. Patients and methods Ethnographic investigations were conducted, including semi- structured qualitative interviews of patients with resected or metastatic/unresectable GIST and their caregivers, from Canada (n = 15); the United States (n = 10); and Brazil, France, Germany, Russia, and Spain (n = 5 each). Some interviewees also kept 7-day photo journals. Responses were qualitatively analyzed to identify gaps and unmet needs where communication about disease, treatments, and adherence could be effective. Results Patients shared common experiences during each stage of disease management (crisis, hope, adaptation, new normal, and uncertainty). Patients felt a sense of crisis during diagnosis, followed by hope upon TKI therapy initiation. Over time, they came to adapt to their new lives (new normal) with cancer. With each follow-up, patients confronted the uncertainty of becoming TKI resistant and the possible need to switch therapy. During uncertainty many patients sought new information regarding GIST. Cases of disease progression and drug switching caused patients to revert to crisis and restart their emotional journey. Patients with primary or unresectable/metastatic GIST shared similar journeys, especially regarding uncertainty, although differences in the scope and timing of phases were observed. Strategies patients used to remain adherent included obtaining family support, setting reminder mechanisms, taking medicine at routine times, and storing medicine in prominent places. Conclusions Physicians and support staff can manage patient

  12. Journey to the Nevada Test Site Radioactive Waste Management Complex

    SciTech Connect

    2007-08-01

    Journey to the Nevada Test Site Radioactive Waste Management Complex begins with a global to regional perspective regarding the location of low-level and mixed low-level waste disposal at the Nevada Test Site. For decades, the Nevada National Security Site (NNSS) has served as a vital disposal resource in the nation-wide cleanup of former nuclear research and testing facilities. State-of-the-art waste management sites at the NNSS offer a safe, permanent disposal option for U.S. Department of Energy/U.S. Department of Defense facilities generating cleanup-related radioactive waste.

  13. Journey to the Nevada Test Site Radioactive Waste Management Complex

    ScienceCinema

    None

    2014-10-28

    Journey to the Nevada Test Site Radioactive Waste Management Complex begins with a global to regional perspective regarding the location of low-level and mixed low-level waste disposal at the Nevada Test Site. For decades, the Nevada National Security Site (NNSS) has served as a vital disposal resource in the nation-wide cleanup of former nuclear research and testing facilities. State-of-the-art waste management sites at the NNSS offer a safe, permanent disposal option for U.S. Department of Energy/U.S. Department of Defense facilities generating cleanup-related radioactive waste.

  14. Aging women's journey toward wholeness: new visions and directions.

    PubMed

    Harris, Margaret T C

    2008-01-01

    Through a postmodern/feminist exploration of postmenopausal women's narratives, set against a backdrop of a discourse analysis of pivotal biomedical texts, we revealed women's menopausal and postmenopausal aging life-cycle journey as a dynamic, positive, empowering women's process. Based on my analysis of themes in women's narratives I argue that the phenomenon of menopause is limited by a reductionist model and that a wholisitic model is more appropriate for women as they negotiate this significant aging life-cycle process to postmenopausal status. Finally, directions for supporting women to develop a wholistic approach to positive adult development, and how the aging woman can be given status, are suggested. PMID:18821209

  15. Unveiling the mystery about adult ADHD: one woman's journey.

    PubMed

    Waite, Roberta; Ivey, Nicole

    2009-09-01

    Attention deficit hyperactivity disorder (ADHD), a neurobiological disorder, affects millions of individuals and can significantly impact an individual's life course. Research guidelines used in assessment, diagnosis, and treatment have focused primarily on Caucasian males generating, in part, the need to redress how gender and other contextual factors are considered. Consequently many women and persons from diverse cultural groups can be ignored or misdiagnosed. Undiagnosed and untreated women with ADHD are therefore limited in their potential to flourish socially, academically, interpersonally, and in their family roles. This case example of a 38-year-old African American woman illustrates how her life journey was affected by undiagnosed ADHD. PMID:19657868

  16. Chronic wound caring ... a long journey toward healing.

    PubMed

    Orsted, H L; Campbell, K E; Keast, D H; Coutts, P; Sterling, W

    2001-10-01

    Healthcare professionals use words like "frustrating," "expensive," and "time-consuming" to describe chronic wound care. Healing a wound that has been present for an extended period of time is difficult. Often the problem is not just the wound but also the "woundedness" of the individual with the wound. The patient's needs in chronic wound care often continue over months, years, or even a lifetime. This article addresses more than the wound--it offers healthcare professionals' accounts of patient stories and their active involvement in the long journey toward chronic wound healing. PMID:11890076

  17. Deforestation in Brazil: motivations, journeys and tendencies

    NASA Astrophysics Data System (ADS)

    Leite, J. C.; Ferreira, A. J. D.; Esteves, T. C. J.; Bento, C. P. M.

    2012-04-01

    José Carlos Leite1; António José Dinis Ferreira2; Tanya Cristina de Jesus Esteves2; Célia Patrícia Martins Bento2 1Universidade Federal de Mato Grosso, Brazil; 2IPC - Escola Superior Agrária de Coimbra, Portugal Over the last three decades, deforestation in Brazil occurred systematically in the area known as the "arc of deforestation", an extensive geographical area located in the interface of the Cerrado and the Amazon biomes. This work encompasses the reasons, causes and/or motivations of that recent deforestation, focusing on the Central-West and Northern regions. A number of reasons will be presented, seeking to build an approach able to identify the deepest roots of deforestation of those regions. Our actions over the environment are framed by our cultural matrix that stream from a western philosophic attitude. This way, to understand the framework where the deforestation actions are justified requires a multidisciplinary approach to understand the deforestation of the Cerrado and Amazon biomes, since the motivations for forest destruction in Brazil are complex and not entirely understood within the domains of a single disciplinary area. To search for an isolated cause to understand the recent deforestation can only be plausible if we ignore information on what actually happens. The methodology used in this work is based on a bibliographical revision, analysis of georeferrenced information, participative processes implementation and observation of stakeholder behavior, and field research. It departs from a general vision on deforestation that initially occurred at the littoral region, by the Atlantic Rainforest, right after the arrival of the Europeans, and throughout the centuries penetrates towards the interior, hitting the Cerrado and Amazon biomes. In this last case, we focused on the Vale do Alto Guaporé region, near Bolivia, where the intensity of the deforestation was verified from 1970 to 1990. Ultimately, the final result is a mosaic of reasons

  18. Learning to reason: a journey of professional socialisation.

    PubMed

    Ajjawi, Rola; Higgs, Joy

    2008-05-01

    One of the key attributes that health professional students and new graduates develop during professional socialisation is clinical reasoning ability. Clinical reasoning is a complex skill that is essential for professional practice. There is limited research specifically addressing how physiotherapists learn to reason in the workplace. The research reported in this paper addressed this gap by investigating how experienced physiotherapists learned to reason in daily practice. This learning journey was examined in the context of professional socialisation. A hermeneutic phenomenological research study was conducted using multiple methods of data collection including observation, written reflective exercises and repeated, semi-structured interviews. Data were analysed using phenomenological and hermeneutic strategies involving in-depth, iterative reading and interpretation to identify themes in the data. Twelve physiotherapists with clinical and supervisory experience were recruited from the areas of cardiopulmonary, musculoskeletal and neurological physiotherapy to participate in this study. Participants' learning journeys were diverse, although certain episodes of learning were common or similar. Role models, mentors and colleagues were found to be influential in the development of reasoning. An important implication for the professional socialisation of physiotherapists and other health professionals and for those involved in practice development is the need to recognise and enhance the role of practice communities in the explicit learning of clinical reasoning skills. PMID:17288004

  19. Accessing Creativity: Jungian Night Sea Journeys, Wandering Minds, and Chaos.

    PubMed

    Rosen, Diane

    2016-01-01

    NDS theory has been meaningfully applied to the dynamics of creativity and psychology. These complex systems have much in common, including a broad definition of "product" as new order emerging from disorder, a new whole (etymologically, 'health') out of disintegration or destabilization. From a nonlinear dynamical systems perspective, this paper explores the far-from-equilibrium zone of creative incubation: first in the Jungian night sea journey, a primordial myth of psychological and creative transformation; then in the neuroscience of mind wandering, the well-spring of creative ideation within the larger neural matrix. Finally, chaos theory grounds the elusive subject of creativity, modeling chaotic generation of idea elements that tend toward strange attractors, combine unpredictably, and produce change by means of tension between opposites, particularly notes consciousness (light) and the poetic unconscious (darkness). Examples from my own artwork illustrate this dialectical process. Considered together, the unconscious mythic sea journey, the unknowing wandering mind, and the generative paradigm of deterministic chaos suggest conditions that facilitate creativity across disciplines, providing fresh indications that the darkness of the unknown or irrational is, paradoxically, the illuminative source and strength of creativity. PMID:26639923

  20. The journey into fatherhood: A grounded theory study.

    PubMed

    Sansiriphun, Nantaporn; Kantaruksa, Kannika; Klunklin, Areewan; Baosuang, Chavee; Liamtrirat, Saowanee

    2015-12-01

    The objective of this study was to explore the process of transition into fatherhood for Thai men from childbirth to the postpartum period. Forty-one first-time Thai fathers were voluntarily recruited from two hospitals in Chiang Mai, Thailand, from December 2012 to June 2013. In-depth interviews were used to collect the data, which were analyzed based on grounded theory methodology. The basic social process that emerged as the core category was termed: "the journey into fatherhood." This process was divided into three phases: labor, delivery, and family beginning. Within this process, there were various situations, challenges, and pressures, which caused many changes of mood and feelings for the first-time fathers. Throughout this process, they applied various strategies to manage their concerns and needs, in order to develop into masterly fathers. Identifying the process of the journey into fatherhood provides nurses and midwives insight into the new fathers' experiences, which will enable them to be more sensitive, respectful, and effective caregivers. PMID:26245824

  1. The reconstruction of the last itinerary of “Ötzi”, the Neolithic Iceman, by pollen analyses from sequentially sampled gut extracts

    NASA Astrophysics Data System (ADS)

    Oeggl, Klaus; Kofler, Werner; Schmidl, Alexandra; Dickson, James H.; Egarter-Vigl, Eduard; Gaber, Othmar

    2007-04-01

    The investigations of the Tyrolean Iceman "Ötzi" and his artefacts, discovered at a remote location high in the Eastern Alps, have contributed greatly to the knowledge of the lifestyle of Neolithic humankind. However, the events immediately prior to the Iceman's death have remained unclear and even the recently discovered arrowhead in his back does not explain conclusively the cause of death satisfactorily. From the pollen and macrofossil content of his gut, we reconstruct his travels just before his demise. Sequential sampling of the food residues in the digestive tract of the 5200 year old glacier mummy has made possible the analyses of a series of meals and, from the pollen content, the deduction of the environments in which the last meals were eaten. During his last 33 or so hours, Ötzi crossed different habitats in the Ötztal mountains over considerable distances from high up near the timber line (at about 2500 m), to low down in the zone of warmth-loving trees (about 1200 m or less), and finally very high in the zone of perennial ice (above 3000 m). These final journeys lend new weight to the "disaster" theory of Ötzi's death, which suggests that, returning from the high alpine pastures to his native village, he came into a severe conflict with his kin such that he had to flee from the community back to the high ground familiar to him, where he died.

  2. UNFINISHED JOURNEY Project. Quarterly report, September 1994--December 1994

    SciTech Connect

    1998-02-01

    In September, 1994, the U.S. Department of Energy (Nevada Operations Office) made a $199,708 grant (through the Mathematics, Science, and Technology Education Program), to the UNFINISHED JOURNEY Project. The Project began in April, 1994, to develop and implement an innovative model of student outreach by San Jose State University (SJSU) to underserved, underrepresented student populations of the East Side Union High School District (ESUHSD). The Project was formed by a consortium involving SJSU, ESUHSD, some 20 private sector organizations (foundations/corporations), numerous local community/professional organizations, and approximately 100 private funders. This proposal to the U.S. Department of Energy was to have the Department join this unique partnership to focus University outreach to underserved student populations to pursue careers in mathematics, science, and technology.

  3. A Journey in Science: Early Lessons from the Hemoglobin Field

    PubMed Central

    Weatherall, David J

    2014-01-01

    Real innovations in medicine and science are historic and singular; the stories behind each occurrence are precious. At Molecular Medicine we have established the Anthony Cerami Award in Translational Medicine to document and preserve these histories. The monographs recount the seminal events as told in the voice of the original investigators who provided the crucial early insight. These essays capture the essence of discovery, chronicling the birth of ideas that created new fields of research; and launched trajectories that persisted and ultimately influenced how disease is prevented, diagnosed, and treated. In this volume, the Cerami Award Monograph is by David J Weatherall, Founder, Weatherall Institute of Molecular Medicine, Oxford University, John Radcliffe Hospital. A visionary in the field of hemoglobin, this is the story of Professor Weatherall’s scientific journey. PMID:25548947

  4. A journey to statistical process control in the development environment

    SciTech Connect

    Hanna, M.; Langston, D.

    1996-12-31

    Over the past 10 years many organizations have undertaken {open_quotes}process reengineering{close_quotes} activities in an attempt to increase their productivity and quality. Unfortunately, the launching point for these reengineering efforts has been based upon the belief that organizational processes either do not exist or they are grossly inefficient. It is the position of the authors that these beliefs are typically unfounded. All ongoing organizations have processes. These processes are effective, based upon the fact they are producing products (or services) that are being purchased. Therefore, the issue is not to invent or reengineer new processes, rather it is to increase the efficiency of the existing ones. This paper outlines a process (or organizational journey) for continually improving process based upon quantitative management techniques and statistical process control methods.

  5. A critical review on the translational journey of cardioprotective therapies!

    PubMed

    Rossello, Xavier; Yellon, Derek M

    2016-10-01

    The failure to translate novel cardioprotective therapies tested in pre-clinical studies into the clinical setting for patient benefit can be attributed to a number of factors at different stages of the research process. This review focuses on the evidences and the gaps with regard to the translational journey of cardioprotective interventions. Gaps are classified into 3 main groups: 1) those related to pre-clinical studies, 2) those associated with the validation of infarct size as a good surrogate and 3) those based on design and interpretation of randomized clinical trials on cardioprotection. Addressing these gaps might increase the chances to successfully translate cardioprotective therapies into improving both post-STEMI heart failure and cardiovascular death rates. PMID:27379920

  6. Toxoplasma gondii dissemination: a parasite's journey through the infected host.

    PubMed

    Harker, K S; Ueno, N; Lodoen, M B

    2015-03-01

    Toxoplasma gondii is a highly successful global pathogen that is remarkable in its ability to infect nearly any nucleated cell in any warm-blooded animal. Infection with T. gondii typically occurs through the ingestion of contaminated food or water, but the parasite then breaches the intestinal epithelial barrier and spreads from the lamina propria to a large variety of other organs in the body. A key feature of T. gondii pathogenesis is the parasite's ability to cross formidable biological barriers in the infected host and enter tissues such as the brain, eye and placenta. The dissemination of T. gondii into these organs underlies the severe disease that accompanies human toxoplasmosis. In this review, we will focus on seminal studies as well as exciting recent findings that have shaped our current understanding of the cellular and molecular mechanisms by which T. gondii journeys throughout the host and enters organs to cause disease. PMID:25408224

  7. Gemini Observatory Takes its Local Communities on an Expanding Journey

    NASA Astrophysics Data System (ADS)

    Harvey, Janice; Michaud, Peter

    2012-08-01

    Currently in its 7th year (2011) Hawaii's annual Journey through the Universe (JttU) program is a flagship Gemini Observatory public education/outreach initiative involving a broad cross-section of the local Hawai'i Island astronomical community, the public, educators, businesses, local government officials, and thousands of local students. This paper describes the program, its history, planning, implementation, as well as the program's objectives and philosophy. The success of this program is documented here, as measured by continuous and expanding engagement of educators, the community, and the public, along with formal evaluation feedback and selected informal verbal testimony. The program's success also serves as justification for the planned adaptation of a version of the program in Chile in 2011 (adapted for Chilean educational and cultural differences). Finally, lessons learned are shared which have refined the program for Gemini's host communities but can also apply to any institution wishing to initiate a similar program.

  8. Journey of a Woman With Terminal Cervical Cancer.

    PubMed

    Kessler, Theresa A

    2016-06-01

    When a cervical cancer diagnosis is made during a terminal stage, a woman is faced with many challenges. Although a terminal illness has many negative effects, such as physical pain, scarring, fear, and sexual dysfunction, women may experience a positive impact on their life, such as improved well-being and a greater appreciation of daily life. The individual experience can lead to personal revelations. Sometimes, the diagnosis can even be seen as a blessing. Understanding a personal experience in a real-life context of the terminal stages of disease is important. This story shares the day-to-day journey of a woman living with a terminal illness of cervical cancer. PMID:27206304

  9. UNFINISHED JOURNEY Project. Quarterly report, April 1995--June 1995

    SciTech Connect

    1998-02-01

    In September, 1994, the U.S. Department of Energy (Nevada Operations Office) made a $199,708 grant (through the Mathematics, Science, and Technology Education Program), to the UNFINISHED JOURNEY Project. The Project began in April, 1994 to develop and implement an innovative model of student outreach by San Jose State University (SJSU) to underserved, underrepresented student populations of the East Side Union High School District (ESUHSD). The Project was formed by a consortium involving SJSU, ESUHSD, some 20 private sector organizations (foundations/corporations), numerous local community/professional organizations, and approximately 100 private funders. This proposal to the U.S. Department of Energy was to have the Department join this unique partnership to focus University outreach to underserved student populations to pursue careers in mathematics, science, and technology.

  10. UNFINISHED JOURNEY Project. Quarterly report, July 1995--September 1995

    SciTech Connect

    1998-02-01

    In September, 1994, the U.S. Department of Energy (Nevada Operations Office) made a $199,708 grant (through the Mathematics, Science, and Technology Education Program), to the UNFINISHED JOURNEY Project. The Project began in April, 1994, to develop and implement an innovative model of student outreach by San Jose State University (SJSU) to underserved, underrepresented student populations of the East Side Union High School District (ESUHSD). The Project was formed by a consortium involving SJSU, ESUHSD, some 20 private sector organizations (foundations/corporations), numerous local community/professional organizations, and approximately 100 private funders. This proposal to the U.S. Department of Energy was to have the Department join this unique partnership to focus University outreach to underserved student populations to pursue careers in mathematics, science, and technology.

  11. Leadership as a Personal Journey: An Indigenous Perspective.

    PubMed

    Doyle, Kerrie; Hungerford, Catherine

    2015-05-01

    Indigenous Australians have higher levels of mental illness, self-harm, suicide and substance abuse than non-Indigenous Australians, as well as more frequent contact with the criminal justice system. These indices point to the need for strong leadership to support Close the Gap programmes that have now been implemented across Australia. This article considers leadership as a journey of learning for Australian Indigenous leaders. Through the use of story, it is suggested that a situational leadership approach, incorporating the principles of mindfulness, provides the most appropriate framework for Indigenous leaders who work with Indigenous communities. Flexible approaches are needed to meet the needs of diverse Indigenous populations, and address the complex challenges involved, including lateral violence. Such flexibility will enable Indigenous leaders and communities to work together to achieve improvements in the health outcomes, not only for Indigenous Australians, but also for Indigenous populations worldwide. PMID:26091079

  12. A New Model of Governance: One University's Journey.

    PubMed

    Brooks, Beth A; Scanlan, Therese

    2015-01-01

    In the nearly 50 years, since the Medicare Program established funding for nursing education in the United States, there has been a steady migration away from hospital-controlled programs toward those which function as wholly owned subsidiaries within larger health care systems. Private sector health care organizations in particular are under increasing pressure to adapt at the risk of losing all of their funding. However, accomplishing this presents multiple challenges for today's nursing education programs in terms of their regulatory compliance, accreditation, autonomy, and, above all, governance model. The authors outline the journey toward, and specific challenges involved in creating, implementing and administering a new governance model, which sustains the overall mission and vision of the education institution while functioning seamlessly within a modern corporate health care system. PMID:25474664

  13. The impact of socioeconomic status on the breast cancer journey.

    PubMed

    Lalani, Nafisha

    2011-03-01

    Socioeconomic status can be defined by educational background and income level. An individual's socioeconomic status impacts all aspects of their lives, and their experience with breast cancer is no exception. As a medical student, I had a chance to work alongside a radiation oncologist at a side effects clinic, where patients are seen periodically to assess any adverse effects of their radiation treatment. Here, I had a chance to see patients during and after the treatment process and to hear their experiences regarding their journey to date. This experience provided me with a glimpse of the disparity that exists between breast cancer survivors of varying backgrounds and highlights the importance of identifying and addressing these issues. PMID:21113698

  14. 'Chaos, restitution and quest': one woman's journey through menopause.

    PubMed

    Nosek, Marcianna; Kennedy, Holly Powell; Gudmundsdottir, Maria

    2012-09-01

    Menopause, a natural stage in a woman's reproductive life, is not an illness; yet some women experience severe enough symptoms to cause a breakdown in the body similar to illness or other major health disruptions. As part of a larger narrative analysis investigation of distress during menopause, this case study presents one woman's transformational journey through menopause, analysed through Frank's health and illness narratives - chaos, restitution and quest. The narratives were retranscribed using Labov's elements of a true story and Gee's poetic restructuring. This report of one woman's experience of distress during the menopause transition describes a poetic chaos narrative of incessant night sweats resulting in a loss of physicality and a deep-rooted belief in self-healing; a restitution narrative of restored health that mandated the surrender to a new healing discourse, experienced simultaneously as a victory and a defeat; and a quest narrative of seeking meaning, insight and new-found values and identities. PMID:22471763

  15. Freud in Trieste: journey to an ambiguous city.

    PubMed

    Gandolfi, Laura

    2010-01-01

    This article provides an insightful exploration of the relationship between Sigmund Freud and the city of Trieste. Through an analysis of the correspondence between Freud and his friend Eduard Silberstein, Gandolfi follows those places visited by the future father of psychoanalysis and analyses their link to Freud's life. The journey to Trieste is considered as an experience that played a fundamental role in his future decisions as well as in the development of some of his psychoanalytic theories. The article eventually relates the ambiguous nature of the city - a peculiar space in with North and South, East and West converge - to Freud's own Triestine experience, that not only remits to his initial scientific researches, but also symbolizes a first significant contact with the world of sexuality. PMID:20842812

  16. A Journey in Science: Medical Scientist in Translation

    PubMed Central

    Hansson, Göran K

    2014-01-01

    Real innovations in medicine and science are historic and singular; the stories behind each occurrence are precious. At Molecular Medicine we have established the Anthony Cerami Award in Translational Medicine to document and preserve these histories. The monographs recount the seminal events as told in the voice of the original investigators who provided the crucial early insight. These essays capture the essence of discovery, chronicling the birth of ideas that created new fields of research; and launched trajectories that persisted and ultimately influenced how disease is prevented, diagnosed and treated. In this volume, the Cerami Award Monograph is by Göran K Hansson, MD, PhD, Karolinska Institute. A visionary in the field of cardiovascular research, this is the story of Dr. Hansson’s scientific journey. PMID:25356751

  17. Early Literacy and Assessment for Learning (K-3) Series: Little Book Insert: Little Honu's Journey

    ERIC Educational Resources Information Center

    Noto, Lee

    2005-01-01

    This illustrated children's story accompanies "Exploring Comprehension through Retelling: A Teacher's Story", part of the Early Literacy and Assessment for Learning (K-3) Series (ED490189). It describes a baby turtle's adventures on his journey to the ocean.

  18. A 25-year wound care journey within the evolution of wound care.

    PubMed

    Harding, Keith G; Queen, Douglas

    2012-02-01

    The journey began for George Winter nearly 50 years ago, using pigs in a laboratory setting, as he observed the healing characteristics of acute wounds. The journey began for industry with the launch of "modern" dressings, particularly with films and hydrocolloids. And so the journey began for authors with a clinical or scientific interest in the art of wound care. For all those who have persevered in the wound care field, their endeavor is not only a vocation, but also a lifelong passion. Although some individuals do not understand such passion, others do, and they are the wound care champions and pioneers who have made this 25-year journey possible and the next 25 years exciting. Much progress has been achieved in wound care in the past 25 years, but much work still remains if the profession is to be truly recognized as a clinical specialty. PMID:22258216

  19. The atomic level journey from aqueous polyoxometalate to metal oxide

    SciTech Connect

    Hou, Yu; Fast, Dylan B.; Ruther, Rose E.; Amador, Jenn M.; Fullmer, Lauren B.; Decker, Shawn R.; Zakharov, Lev N.; Dolgos, Michelle R. Nyman, May

    2015-01-15

    Aqueous precursors tailored for the deposition of thin film materials are desirable for sustainable, simple, low energy production of advanced materials. Yet the simple practice of using aqueous precursors is complicated by the multitude of interactions that occur between ions and water during dehydration. Here we use lithium polyoxoniobate salts to investigate the fundamental interactions in the transition from precursor cluster to oxide film. Small-angle X-ray scattering of solutions, total X-ray scattering of intermediate gels, and morphological and structural characterization of the lithium niobate thin films reveal the atomic level transitions between these states. The studies show that (1) lithium–[H{sub 2}Nb{sub 6}O{sub 19}]{sup 6−} has drastically different solution behaviour than lithium–[Nb{sub 6}O{sub 19}]{sup 8−}, linked to the precursor salt structure (2) in both compositions, the intermediate gel preserves the polyoxoniobate clusters and show similar local order and (3) the morphology and phases of deposited films reflect the ions behaviour throughout the journey from cluster solution to metal oxide. - Graphical abstract: Aqueous lithium polyoxoniobate salts were used to prepare lithium niobate (LiNbO{sub 3}) thin films. Fundamental studies were performed to investigate the interactions in the transition from precursor cluster to the oxide film. It was found that acid–base and ion-association chemistries of the aqueous and gel systems significantly affect the key processes in this atom-level journey. - Highlights: • Lithium polyoxoniobate clusters were synthesized with control over Li:Nb ratio as precursors for LiNbO{sub 3} films. • X-ray scattering studies in solution and the solid-state revealed differences controlled by Li:Nb ratio. • Film deposition studies revealed phase, composition and morphology is controlled by Li:Nb ratio. • Cluster to film transformation was revealed using total X-ray scattering and TGA.

  20. Journey-time exposure to particulate air pollution

    NASA Astrophysics Data System (ADS)

    Gulliver, John; Briggs, David J.

    Journey-time exposures to particulate air pollution were investigated in Leicester, UK, between January and March 2005. Samples of TSP, PM 10, PM 2.5, and PM 1 were simultaneously collected using light scattering devices whilst journeys were made by walking an in-car. Over a period of two months, 33 pairs of walking and in-car measurements were collected along two circular routes. Average exposures while walking were seen to be higher than those found in-car for each of the particle fractions: average walking to in-car ratios were 1.2 (± 0.6), 1.5 (± 0.6), 1.3 (± 0.6), and 1.4 (± 0.6) μg m -3 for coarse (TSP-PM 10), intermediate (PM 10-PM 2.5), fine (PM 2.5-PM 1), and very fine particles (PM 1), respectively. Correlations between walking and in-car exposures were seen to be weak for coarse particles ( r=0.10, p=0.58), moderate for the intermediate particles ( r=0.49, p<0.01) but strong for fine ( r=0.89, p<0.01) and very fine ( r=0.90, P<0.01) particles. PM 10 exposures while walking were on average 70% higher than a nearby roadside fixed-site monitor whilst in-car exposures were 25% higher than the same fixed-site monitor. Particles with an aerodynamic diameter of less than 2.5 μm were seen to be highly correlated between walking and in-car particle exposures and a rural fixed-site monitor about 30 km south of Leicester.

  1. Becoming a blind teacher in Turkey: A long journey.

    PubMed

    Koca-Atabey, Müjde

    2016-06-01

    The story of Hakan profoundly calls attention to the dialectical relationship between the macro and the micro influences on the social and political situated nature of disability, work life expectations and the transformative power of life-long learning. All of these are reflected in Hakan's journey and his capacity to self-manage his needs and adapt in spite of disability adversity and impairment challenges at the turning points in his life. He used his ingenuity when faced with challenges by tapping into non-disabling environments (finding a university program that fit with his needs and he was able to meet standard examination expectations) and familiar human relationships (finding friends or family that agreed to read to him). His early experiences in the formal and informal labour markets that were available to him provided grounding into various workplace acumen and social requirements. In effect these experiences were part of his early employment socialization that are often overlooked as essential to being ready to shift from a job to deciding on a career in a changing labour economy. While Hakan developed his capacity and competencies to be ready for work in a viable career, the policy's of prescriptive employment for the disabled shifted slightly to open up the door to more persons with impairments. Read on to find out the details of Hakan's numerous experiences with turning points, shifts and his efforts to persist in becoming a teacher. Following this article there are reflective questions for deeper consideration and contemplation of the many relationships that shaped the journey. PMID:27286073

  2. The Candle and the Mirror: One Author's Journey as an Outsider.

    ERIC Educational Resources Information Center

    Moreillon, Judi

    1999-01-01

    Chronicles the author's journey as an outsider who authored a book for children about the harvest traditions of the Tohono O'odham people. Describes how her concern about the lack of literature to serve as a mirror and a candle to reflect and illuminate the lives of Tohono O'odham children led her on a journey that was both painful and affirming.…

  3. “A journey around the world”: Parent narratives of the journey to pediatric resective epilepsy surgery and beyond

    PubMed Central

    Baca, Christine B.; Pieters, Huibrie C.; Iwaki, Tomoko J.; Mathern, Gary W.; Vickrey, Barbara G.

    2015-01-01

    OBJECTIVE Although shorter time to pediatric resective epilepsy surgery is strongly associated with greater disease severity, other non-clinical diagnostic and sociodemographic factors also play a role. We aimed to examine parent-reported barriers to timely receipt of pediatric epilepsy surgery. METHODS We conducted 37 interviews of parents of children who previously had resective epilepsy surgery at UCLA (2006–2011). Interviews were audio-recorded, transcribed and systematically coded using thematic analysis by two independent coders and subsequently checked for agreement. Clinical data, including `time to surgery' (age of epilepsy onset to surgery) were abstracted from medical records. RESULTS The mean time to surgery was 5.3 years (SD=3.8); surgery types included 32% hemispherectomy, 43% lobar/focal, 24% multilobar. At surgery, parents were on average 38.4 years (SD=6.6) and children were 8.2 years (SD=4.7). The more arduous and longer aspect of the journey to surgery was perceived by parents to be experienced prior to presurgical referral. The time from second anti-epileptic drug failure to presurgical referral was ≥1 year in 64% of children. Thematic analysis revealed four themes (with subthemes) along the journey to surgery and beyond: (1) recognition: “something is wrong” (unfamiliarity with epilepsy, identification of medical emergency), (2) searching and finding: “a circuitous journey” (information seeking, finding the right doctors, multiple medications, insurance obstacles, parental stress), (3) surgery is a viable option: “the right spot” (surgery as last resort, surgery as best option, hoping for candidacy), and (4) life now: “we took the steps we needed to” (a new life, giving back). SIGNIFICANCE Multi-pronged interventions targeting parent-, provider- and system-based barriers should focus on the critical presurgical referral period; such interventions are needed to remediate delays and improve access to subspecialty care for

  4. Journey to the Center of a Neutron Star

    NASA Technical Reports Server (NTRS)

    Wanjek, Christopher

    2003-01-01

    A neutron star is not a place most would want to visit. This dense remnant of a collapsed star has a magnetic field billions of times stronger than Earth's, enough to shuffle your body's molecules long before you even land. The featureless surface is no fun either. Crushing gravity ensures that the star is a near perfect sphere, compressing all matter so that a sand-grain-sized scoop of neutron star material would weigh as much as a battleship on Earth. At least black holes offer the promise of funky singularity, time warps, and the Odyssean temptation to venture beyond a point of no return. What s a journey to a neutron star good for, one might ask? Well, for starters, it offers the possibility of confirming a theorized state of matter called quark-gluon plasma, which likely existed for a moment after the Big Bang and now might only exist in the superdense interiors of neutron stars. Beneath the neutron star crust, a kilometer-thick plate of crystalline matter, lies the great unknown. The popular theory is that the neutron star interior is made up of a neutron superfluid - a fluid without friction. With the help of two NASA satellites - the Rossi X-Ray Timing Explorer and the Chandra X-Ray Observatory - scientists are journeying to the center of a neutron star. Matter might be so compressed there that it breaks down into quarks, the building blocks of protons and neutrons, and gluons, the carrier of the strong nuclear force. To dig inside a neutron star, no simple drill bit will do. Scientists gain insight into the interior through events called glitches, a sudden change in the neutron star s precise spin rate. 'Glitches are one of the few ways we have to study the neutron star interior,' says Frank Marshall of NASA s Goddard Space Flight Center, who has used the Rossi Explorer to follow the escapades of the glitchiest of all neutron stars, dubbed the Big Glitcher and known scientifically as PSR J0537-6910.

  5. A 50-Year Journey to Cure Childhood Acute Lymphoblastic Leukemia

    PubMed Central

    Pui, Ching-Hon; Evans, William E.

    2013-01-01

    The 50th anniversary of Seminars in Hematology coincides with the 50th of St. Jude Children’s Research Hospital, and both milestones are inexorably linked to studies contributing to the cure of childhood acute lymphoblastic leukemia (ALL). We thought it fitting, therefore, to mark these events by traveling back in time to point out some of the achievements, institutions, study groups and individuals that have made cure of childhood ALL a reality. In many instances, progress was driven by new ideas, while in others it was driven by new experimental tools that allowed more precise assessment of the biology of leukemic blasts and their utility in selecting therapy. We also discuss a number of contemporary advances that point the way to exciting future directions. Whatever pathways are taken, a clear challenge will be to use emerging genome-based or immunologic-based treatment options in ways that will enhance, rather than duplicate or compromise, recent gains in outcome with classic cytotoxic chemotherapy. The theme of this journey serves as a reminder of the chief ingredient of any research directed to a catastrophic disease such as ALL. It is the audacity of a small group of investigators who confronted a childhood cancer with the goal of cure, not palliation, as their mindset. PMID:23953334

  6. The innovation journey of genomics and asthma research.

    PubMed

    Bitsch, Lise; Stemerding, Dirk

    2013-11-01

    This article concerns the transformative potential of medical genomics for common disease research. We analysed 13 review articles in asthma research in the period 1999 to 2008. Our aim was to understand how genomics has emerged in this research field, and the attendant changes. Motivated by Lippman's geneticisation thesis, we use the concept of an 'innovation journey' to trace how expectations of improved understanding, prevention, diagnosis and treatment structure a dynamic co-evolutionary process through which a genome-based discourse emerges. We show how the asthma researchers involved continuously struggle to define their contribution to asthma research, as well as to clinical practice. Along the way, the researchers propose changes to both the definition and the aetiological model of asthma, thus highlighting gene-gene and gene-environment interactions. It is, however, difficult to characterise this discourse as one of geneticisation. With increasing attention being given to epigenetics, metabolomics, proteomics and systems biology, the emerging picture suggests an important, but much less deterministic, role for genes. PMID:23551185

  7. Peptide signalling during the pollen tube journey and double fertilization.

    PubMed

    Qu, Li-Jia; Li, Ling; Lan, Zijun; Dresselhaus, Thomas

    2015-08-01

    Flowering seed plants (angiosperms) have evolved unique ways to protect their gametes from pathogen attack and from drying out. The female gametes (egg and central cell) are deeply embedded in the maternal tissues of the ovule inside the ovary, while the male gametes (sperm cells) are enclosed in the vegetative pollen tube cell. After germination of the pollen tube at the surface of papilla cells of the stigma the two immobile sperm cells are transported deep inside the sporophytic maternal tissues to be released inside the ovule for double fertilization. Angiosperms have evolved a number of hurdles along the pollen tube journey to prevent inbreeding and fertilization by alien sperm cells, and to maximize reproductive success. These pre-zygotic hybridization barriers require intensive communication between the male and female reproductive cells and the necessity to distinguish self from non-self interaction partners. General molecules such as nitric oxide (NO) or gamma-aminobutyric acid (GABA) therefore appear to play only a minor role in these species-specific communication events. The past 20 years have shown that highly polymorphic peptides play a leading role in all communication steps along the pollen tube pathway and fertilization. Here we review our current understanding of the role of peptides during reproduction with a focus on peptide signalling during self-incompatibility, pollen tube growth and guidance as well as sperm reception and gamete activation. PMID:26068467

  8. Media Fellow Journeys to the “Other Side”

    NASA Astrophysics Data System (ADS)

    Weiss, Marissa

    2011-03-01

    On the heels of defending my Ph.D. in soil ecology, I headed off to northern Colorado last September for the next step in my scientific journey: working at a radio station. AGU was sponsoring me as a mass media fellow, a scientist-reporter temporarily working at a news media outlet. In graduate school I had pursued some science writing training, but I had never been employed as a journalist. I hoped the experience would help me understand why it can be hard for scientists and journalists to communicate with each other and what the barriers are to providing accurate and comprehensive coverage of science in the media. That's the kind of understanding that the fellowship program, run by the American Association for the Advancement of Science, was meant to promote. It helps scientists learn from experience about how science reporting is done, and in an age when science desks have been eliminated by most major news outlets, it puts an eye on science back in the newsroom.

  9. Measuring a Journey without Goal: Meditation, Spirituality, and Physiology

    PubMed Central

    Buttle, Heather

    2015-01-01

    The secular practice of meditation is associated with a range of physiological and cognitive effects, including lower blood pressure, lower cortisol, cortical thickening, and activation of areas of the brain associated with attention and emotion regulation. However, in the context of spiritual practice, these benefits are secondary gains, as the primary aim is spiritual transformation. Despite obvious difficulties in trying to measure a journey without goal, spiritual aspects involved in the practice of meditation should also be addressed by experimental study. This review starts by considering meditation in the form of the relaxation response (a counterpart to the stress response), before contrasting mindfulness research that emphasizes the role of attention and alertness in meditation. This contrast demonstrates how reference to traditional spiritual texts (in this case Buddhist) can be used to guide research questions involving meditation. Further considerations are detailed, along with the proposal that research should triangulate spiritual textual sources, first person accounts (i.e., neurophenomenology), and physiological/cognitive measures in order to aid our understanding of meditation, not only in the secular context of health benefits, but also in the context of spiritual practice. PMID:26137495

  10. Measuring a Journey without Goal: Meditation, Spirituality, and Physiology.

    PubMed

    Buttle, Heather

    2015-01-01

    The secular practice of meditation is associated with a range of physiological and cognitive effects, including lower blood pressure, lower cortisol, cortical thickening, and activation of areas of the brain associated with attention and emotion regulation. However, in the context of spiritual practice, these benefits are secondary gains, as the primary aim is spiritual transformation. Despite obvious difficulties in trying to measure a journey without goal, spiritual aspects involved in the practice of meditation should also be addressed by experimental study. This review starts by considering meditation in the form of the relaxation response (a counterpart to the stress response), before contrasting mindfulness research that emphasizes the role of attention and alertness in meditation. This contrast demonstrates how reference to traditional spiritual texts (in this case Buddhist) can be used to guide research questions involving meditation. Further considerations are detailed, along with the proposal that research should triangulate spiritual textual sources, first person accounts (i.e., neurophenomenology), and physiological/cognitive measures in order to aid our understanding of meditation, not only in the secular context of health benefits, but also in the context of spiritual practice. PMID:26137495

  11. A journey of no return and no regrets.

    PubMed

    Yeh, Nai-Chang

    2010-06-01

    This article describes the author's personal journey from childhood to a career in physics. The beauty and truth that the author finds in physics has been the primary driving force and inspiration for her relentless pursuit of knowledge and her constant push for cutting-edge research, despite all obstacles and odds against her as a "double minority" (an Asian woman) in a predominantly white male profession. Based on her 20 years of research and teaching at one of the world's leading academic institutions, the California Institute of Technology, the author observes no differences between men and women in their scientific talents, thereby dispelling the misconception of possible inferiority of women as scientists. She further stresses the urgent societal needs for more talent in various sciences to address many of the important issues facing the planet. In this context, society must promote gender equality in science so that one half of the talent does not go to waste. Finally, the author shares her thoughts with young people about how to be better prepared to face the challenges in life and fulfill their dreams. PMID:20538242

  12. Digital engagement in nursing: a urology nurse's journey.

    PubMed

    Brocksom, Jane E

    The use of technology is transforming society-underpinning communication, information gathering and collaboration. Indeed, 2013 may prove to be the tipping point for healthcare delivery. No longer are policies and guidance documents being produced solely on the basis of cautions and negatives. We are entering a new era. Documents are now being produced that are constructive, focusing equally on positives and collaboration. Digital engagement within nursing and healthcare communities can be a tremendously positive experience; with the help of online resources, we can be part of the tipping point. From micro blogging to content communities, from collaborative projects to social networking, Web2.0 technology is providing 21st-century practitioners with opportunities we have not yet fully realised the potential of-for ourselves, our patients or our institutions. In this article, I share my personal journey, aiming to show my fellow healthcare practitioners how these technologies might be used to inform and improve nursing practice, within urology and beyond. PMID:24121770

  13. Transparency in a Pediatric Quality Improvement Collaborative: A Passionate Journey by NPC-QIC Clinicians and Parents.

    PubMed

    Lihn, Stacey L; Kugler, John D; Peterson, Laura E; Lannon, Carole M; Pickles, Diane; Beekman, Robert H

    2015-01-01

    Transparency-sharing data or information about outcomes, processes, protocols, and practices-may be the most powerful driver of health care improvement. In this special article, the development and growth of transparency within the National Pediatric Cardiology Quality Improvement Collaborative is described. The National Pediatric Cardiology Quality Improvement Collaborative transparency journey is guided by equal numbers of clinicians and parents of children with congenital heart disease working together in a Transparency Work Group. Activities are organized around four interrelated levels of transparency (individual, organizational, collaborative, and system), each with a specified purpose and aim. A number of Transparency Work Group recommendations have been operationalized. Aggregate collaborative performance is now reported on the public-facing web site. Specific information that the Transparency Work Group recommends centers provide to parents has been developed and published. Almost half of National Pediatric Cardiology Quality Improvement Collaborative centers participated in a pilot of transparently sharing their outcomes achieved with one another. Individual centers have also begun successfully implementing recommended transparency activities. Despite progress, barriers to full transparency persist, including health care organization concerns about potential negative effects of disclosure on reputation and finances, and lack of reliable definitions, data, and reporting standards for fair comparisons of centers. The National Pediatric Cardiology Quality Improvement Collaborative's transparency efforts have been a journey that continues, not a single goal or destination. Balanced participation of clinicians and parents has been a critical element of the collaborative's success on this issue. Plans are in place to guide implementation of additional transparency recommendations across all four levels, including extension of the activities beyond the

  14. In Pursuit of Pleasure: Health Education as a Means of Facilitating the "Health Journey" of Young People

    ERIC Educational Resources Information Center

    Whitehead, Dean

    2005-01-01

    Purpose: To highlight recently emerging issues and discussions related to the "health journey" of young people, and how health education interventions may be best applied in light of these. Design/methodology/approach: A general review of the "health journey" phenomena in young people is explored. Findings: Many health education interventions…

  15. They Self-Ignited: Adult Student Journeys to an Associate's Degree While Active Duty Military or Military Spouse

    ERIC Educational Resources Information Center

    Bibus, Lindsay Pohl

    2013-01-01

    This qualitative study was undertaken in order to gain an understanding of the lived experiences of adult students and how they made meaning of their journey. To that end, through in-depth interviews with twenty participants, the study inquired into the journeys to an associate's degree of adult students who were also active duty military service…

  16. Reflections on a Mutual Journey of Discovery and Growth Based on a Japanese-South African Collaboration

    ERIC Educational Resources Information Center

    Ono, Y.; Chikamori, K.; Shongwe, Z. F.; Rogan, J. M.

    2011-01-01

    In this article we portray our personal journeys in a cross-cultural context resulting in professional growth. Data are presented in the form of constructed dialogues, and are reflected upon using the theories of transformative learning and intercultural competency. The role of lesson study as a vehicle for our journeys is examined. Reflection on…

  17. Patterns and durations of journeys by horses transported from the USA to Canada for slaughter.

    PubMed

    Roy, R Cyril; Cockram, Michael S

    2015-06-01

    Concern has been expressed over the welfare of horses transported from the USA for slaughter in Canada. United States Department of Agriculture owner/shipper certificates for the year 2009 were analyzed to provide quantitative information on the patterns and durations of these journeys. In 2009, horses from 16 states in the northern USA were transported to 6 equine slaughter plants in Canada. Thirty-two percent of loads were from auction centers, 33% from feedlots, and 35% from horse collection centers. The median duration of the journey was 19 h. Thirty-six percent of horses were transported for < 6 h, 11% for 6 to 18 h, 13% for 18 to 24 h, 25% for 24 to 36 h, 9% for 36 to 48 h, and apparently 6% > 48 h. Some journeys exceeded those specified in regulations and, based on other research, would put these horses at risk of negative welfare outcomes, such as dehydration, injury, and fatigue. PMID:26028678

  18. Patterns and durations of journeys by horses transported from the USA to Canada for slaughter

    PubMed Central

    Roy, R. Cyril; Cockram, Michael S.

    2015-01-01

    Concern has been expressed over the welfare of horses transported from the USA for slaughter in Canada. United States Department of Agriculture owner/shipper certificates for the year 2009 were analyzed to provide quantitative information on the patterns and durations of these journeys. In 2009, horses from 16 states in the northern USA were transported to 6 equine slaughter plants in Canada. Thirty-two percent of loads were from auction centers, 33% from feedlots, and 35% from horse collection centers. The median duration of the journey was 19 h. Thirty-six percent of horses were transported for < 6 h, 11% for 6 to 18 h, 13% for 18 to 24 h, 25% for 24 to 36 h, 9% for 36 to 48 h, and apparently 6% > 48 h. Some journeys exceeded those specified in regulations and, based on other research, would put these horses at risk of negative welfare outcomes, such as dehydration, injury, and fatigue. PMID:26028678

  19. Biofuels and the role of space in sustainable innovation journeys.

    PubMed

    Raman, Sujatha; Mohr, Alison

    2014-02-15

    This paper aims to identify the lessons that should be learnt from how biofuels have been envisioned from the aftermath of the oil shocks of the 1970s to the present, and how these visions compare with biofuel production networks emerging in the 2000s. Working at the interface of sustainable innovation journey research and geographical theories on the spatial unevenness of sustainability transition projects, we show how the biofuels controversy is linked to characteristics of globalised industrial agricultural systems. The legitimacy problems of biofuels cannot be addressed by sustainability indicators or new technologies alone since they arise from the spatial ordering of biofuel production. In the 1970-80s, promoters of bioenergy anticipated current concerns about food security implications but envisioned bioenergy production to be territorially embedded at national or local scales where these issues would be managed. Where the territorial and scalar vision was breached, it was to imagine poorer countries exporting higher-value biofuel to the North rather than the raw material as in the controversial global biomass commodity chains of today. However, controversy now extends to the global impacts of national biofuel systems on food security and greenhouse gas emissions, and to their local impacts becoming more widely known. South/South and North/North trade conflicts are also emerging as are questions over biodegradable wastes and agricultural residues as global commodities. As assumptions of a food-versus-fuel conflict have come to be challenged, legitimacy questions over global agri-business and trade are spotlighted even further. In this context, visions of biofuel development that address these broader issues might be promising. These include large-scale biomass-for-fuel models in Europe that would transform global trade rules to allow small farmers in the global South to compete, and small-scale biofuel systems developed to address local energy needs in the

  20. A journey into medical physics as viewed by a physicist

    NASA Astrophysics Data System (ADS)

    Gueye, Paul

    2007-03-01

    The world of physics is usually linked to a large variety of subjects spanning from astrophysics, nuclear/high energy physics, materials and optical sciences, plasma physics etc. Lesser is known about the exciting world of medical physics that includes radiation therapy physics, medical diagnostic and imaging physics, nuclear medicine physics, and medical radiation safety. These physicists are typically based in hospital departments of radiation oncology or radiology, and provide technical support for patient diagnosis and treatment in a clinical environment. This talk will focus on providing a bridge between selected areas of physics and their medical applications. The journey will first start from our understanding of high energy beam production and transport beamlines for external beam treatment of diseases (e.g., electron, gamma, X-ray and proton machines) as they relate to accelerator physics. We will then embrace the world of nuclear/high energy physics where detectors development provide a unique tool for understanding low energy beam distribution emitted from radioactive sources used in Brachytherapy treatment modality. Because the ultimate goal of radiation based therapy is its killing power on tumor cells, the next topic will be microdosimetry where responses of biological systems can be studied via electromagnetic systems. Finally, the impact on the imaging world will be embraced using tools heavily used in plasma physics, fluid mechanics and Monte Carlo simulations. These various scientific areas provide unique opportunities for faculty and students at universities, as well as for staff from research centers and laboratories to contribute in this field. We will conclude with the educational training related to medical physics programs.

  1. Improving Ourselves for the Sake of Others: Our Baldrige Journey.

    PubMed

    Pope, Jayne E; Padula, Emily; Wallace-Dooley, Debbye

    2015-01-01

    In today's healthcare environment, healthcare organizations are trying to balance one foot in each oftwo boats: one for traditional fee-for-service reimbursement and one for population health and pay-for-quality reimbursement. The Baldrige Performance Excellence Program and its associated Criteria will help healthcare leaders navigate this changing environment and improve healthcare outcomes for patients while improving financial performance, enhancing the patient experience, and creating a positive work environment. This balanced approach, grounded in behaviors identified in high-performing organizations, provides leaders and their teams with the key to realizing strategic goals and long-term sustainability. The Baldrige Criteria alone will not improve an organization; rather, it is the unique and disciplined application of the Criteria to each organization that makes the difference. A Baldrige journey is not a sprint, but rather a marathon; it requires a long-term commitment to improvement at all levels of the organization. At Hill Country Memorial (HCM) Hospital in Fredericksburg, Texas, we selected the Baldrige Framework to guide our team as we embarked on a performance excellence climb that would take us from merely average to the national top io percent of performance as evaluated on important organizational metrics. HCM did not achieve overnight success; instead, we achieved year-over-year improvement in finance and growth, patient experience, quality of care, and workforce environment and engagement. The story of our climb is one of perseverance, willingness to learn from our mistakes, pursuit of innovative best practices both inside and outside of healthcare, and a team committed to providing the highest-quality service to our customers--our patients and our community. PMID:26492731

  2. Water's Journey from Rain to Stream in perspective

    NASA Astrophysics Data System (ADS)

    Rodhe, Allan; Grip, Harald

    2015-04-01

    The International Hydrological Decade (IHD) 1965-1974, sponsored by UNESCO, initiated a research effort for coordinating the fragmented branches of hydrology and for understanding and quantifying the hydrologic cycle on various scales, from continents to small catchments. One important part of the Swedish IHD-program was to quantify the terms of the water budget, including detailed data on soil water and groundwater storage dynamics, of several medium sized to small. As an outcome of these studies and subsequent process oriented studies, a new view of the runoff process in forested till soils was developed in the 1970's, stressing the dominating role of groundwater in delivering water to the streams and the usefulness of subdividing catchments into recharge and discharge areas for groundwater for understanding the flowpaths of water. This view contrasted with the general view among the public, and also among professionals within the field and in text books, according to which overland flow is the main process for runoff. With this latter view it would, for instance, not be possible to understand stream water chemistry, which had become an important question in a time of growing environmental concern. In order to decrease the time lag between research results and practice, the Swedish Natural Science Research Council initiated a text book project for presenting the recent results of hydrologic research on stream flow generation applied to Swedish conditions, and in 1985 our book "Water's Journey from Rain to Stream" was published. Founded on the basic principles for water storage and flow in soils, the book gives a general picture of the water flow through the forested till landscape, with separate chapters for recharge and discharge areas. Chemical processes along the flowpaths of water are treated and the book concludes with a few applications to current issues. The book is written in Swedish and the target audience is those working professionally with water and

  3. A graduate curriculum guided by human becoming: journeying with the possible.

    PubMed

    Milton, Constance L

    2003-07-01

    Graduate education involves teaching-learning processes and experiences where faculty and students journey with adventure and trepidation all-at-once. In this column, notions regarding graduate education where the educational curriculum is guided by the human becoming school of thought as a conceptual framework are explored. Opportunities and challenges from both faculty and student perspectives are highlighted. PMID:12876878

  4. The Visualization of Education Policy: A Videological Analysis of "Learning Journeys"

    ERIC Educational Resources Information Center

    Koh, Aaron

    2009-01-01

    The attention to the visualization of education policy is an area of study yet to be developed and explored. This paper extends the scholarship of "mediated education policy production" by developing a visual methodology to analyse a visual education policy document that takes the form of a documentary titled "Learning Journeys" (2000), which…

  5. Internationalizing Teacher Education: One University's Journey from Awareness to Action

    ERIC Educational Resources Information Center

    Hansen, C. Bobbi

    2013-01-01

    In the 21st century, it is more important than ever to include global/international education as an essential component of teacher education programs. This paper showcases one Department of Education's journey to internationalize its teacher credential program. Components of the reform include: 1) shared conversations, 2) goal-setting, 3)…

  6. Selah, a Precious Mosaic: A Mother's Journey through Autism with Her Deaf Child

    ERIC Educational Resources Information Center

    Ellis-Gonzales, Stefanie D.

    2008-01-01

    When the author learned that her daughter, Selah, had autism, she and her husband were shaken to the core and were terrified of what lay ahead of them. Selah's autism has redefined many things for them. In this article, the author describes her journey through autism with her deaf child.

  7. Four Stages and Four Wisdom Lessons: Harry Potter and the Male Spiritual Journey

    ERIC Educational Resources Information Center

    Evans, Allen

    2005-01-01

    The "Harry Potter" series has proven to be immensely popular to readers of all ages worldwide. In particular, the series has strong appeal to boys. This paper examines selected characters and events from the books in light of the "male spiritual journey," a concept currently being explored by Richard Rohr and others. A general definition of…

  8. The Journey to School: Space, Geography and Experiences of Rural Children

    ERIC Educational Resources Information Center

    Morojele, Pholoho; Muthukrishna, Nithi

    2012-01-01

    This paper gives prominence to rural children's accounts of their journey to school. Twelve children (male = 6; female = 6) from three different rural villages in Lesotho participated in the study. Individual and focus group interviews were used to generate data, and these were preceded by three participatory research techniques: family drawings,…

  9. How Good Is Our School? The Journey to Excellence: Part 3

    ERIC Educational Resources Information Center

    Her Majesty's Inspectorate of Education, 2007

    2007-01-01

    This revised edition of "How good is our school?" replaces all previous versions. Along with a revised edition of "Child at the Centre," this document forms the third part of "How good is our school? The Journey to Excellence." The set of quality indicators continue to provide the core tool for self-evaluation for all schools, but they are now…

  10. The Making of Griots: One Black Filmmaker's Journey with Six Teenagers

    ERIC Educational Resources Information Center

    Dowdy, Joanne Kilgour; Reedus, Narcel G.; Anderson-Thompkins, Sibby; Heim, Patricia Lee

    2003-01-01

    The Media Project was created to facilitate the journey of "inner city" high school students as they learned to make their first short films. Their leader chose to enlist the support of a professional cinematographer, production manager, editor, and director, to see that the final short films are of a high quality. The six teenagers experienced…

  11. Joseph Campbell, Jung, Anne Tyler, and "The Cards": The Spiritual Journey in "Searching for Caleb."

    ERIC Educational Resources Information Center

    Thomson, Karen M.

    Joseph Campbell, Carl Jung, and Anne Tyler have all dealt with spiritual journeys and card reading in their writings. In his book "Tarot Revelations," Joseph Campbell discusses his first association with tarot cards, dating from 1943, when he was introduced to the symoblism of playing cards by his friend and mentor, Heinrich Zimmer. Carl Jung was…

  12. Bridging Identity "Chasms": Occupational Therapy Academics' Reflections on the Journey towards Scholarship

    ERIC Educational Resources Information Center

    Fortune, Tracy; Ennals, Priscilla; Bhopti, Anoo; Neilson, Cheryl; Darzins, Susan; Bruce, Christopher

    2016-01-01

    The performative context of higher education demands that practice-oriented academics shift their priorities from preparing practitioners for the profession, towards "productive" scholarship. We present narratives from occupational therapy academics at the end of a year-long journey through an action research project focussed on academic…

  13. Boundary Management in Doctoral Supervision: How Supervisors Negotiate Roles and Role Transitions throughout the Supervisory Journey

    ERIC Educational Resources Information Center

    Benmore, Anne

    2016-01-01

    In this paper, boundary management illuminates understanding of the doctoral supervisory relationship. Boundary management is presented as a theoretical vehicle that helps to define and explain roles that supervisors employ at different junctures along the doctoral journey and how transitions between these are negotiated. The paper draws on the…

  14. Examining the Influence of Technology and Project-Supported Thinking Journey on Achievement

    ERIC Educational Resources Information Center

    Baran, Medine; Maskan, Abdulkadir

    2013-01-01

    The purpose of this study was to investigate the influence of the technology and project-supported Thinking Journey on 11th grade high school students' achievements in the subject of electricity units. The participants were 68 high school 11th grade students from two different science classes. Control and experimental groups were selected at…

  15. Lester B. Pearson Elementary School: First Year on a Journey with the Change Process

    ERIC Educational Resources Information Center

    Normore, Anthony H.

    2004-01-01

    The case is intended for use as a culminating experience in courses, seminars or workshops that deal with organizational behaviour and the change process. It expounds on the key steps in any systemic change process involving one school's journey with change as it sets priorities and strategies, the problems encountered, where the support and…

  16. Mapping the Journey from Home to School: A Study on Children's Representation of Space

    ERIC Educational Resources Information Center

    Thommen, Evelyne; Avelar, Silvania; Sapin, Veronique Zbinden; Perrenoud, Silvia; Malatesta, Dominique

    2010-01-01

    This paper describes a study conducted with 235 children from Brazil and Switzerland. The children, from 5 to 13 years of age, were asked to draw the journey they undertake every day from home to school. The purpose of the study is to understand the relationship between the cognitive development and map-drawing abilities of children in both…

  17. One Library Media Specialist's Journey to Understanding Advocacy: A Tale of Transformation

    ERIC Educational Resources Information Center

    Levitov, Deborah

    2007-01-01

    In this article, the author traces her journey from fulfilling her evolving job duties to an increased sense of awareness that advocacy was an integral part of her work. The author started her career by doing the best she could do for the library media program she managed, and evolved to become an advocate for school libraries in general. Through…

  18. Lewis & Clark: The Journey of the Corps of Discovery. Teacher's Guide and Video Segment Index.

    ERIC Educational Resources Information Center

    Public Broadcasting Service, Washington, DC.

    This teacher's guide accompanies the Public Broadcasting System (PBS) four-part videotape documentary about the journey of Meriwether Lewis and William Clark as they made their way from the Missouri River to the Pacific Ocean. The guide introduces the documentary's major themes through 4 lessons which focus on the geography and events that shaped…

  19. A Journey from STEM to STEAM: A Middle School Case Study

    ERIC Educational Resources Information Center

    Hunter-Doniger, Tracey; Sydow, Lindsey

    2016-01-01

    This article examines the initial journey of a middle school in South Carolina from a STEM (science, technology, engineering, and math) curriculum to a STEAM (STEM + art) curriculum. This is the first of a three-year longitudinal study that investigated the perceptions of the effectiveness, relative importance, and sustainability of a STEAM…

  20. Development and Evaluation of an Educational Display for Older Adults: Journey through Health

    ERIC Educational Resources Information Center

    Jung, Seung Eun; Hermann, Janice; Parker, Stephany; Smith, Brenda J.

    2015-01-01

    The Journey Through Health educational display was developed using the Health Belief Model and provided information on how the Dietary Guidelines Consumer Brochure messages can positively influence nutrition and physical activity choices to prevent or delay age-related changes throughout the body. The display consisted of 12 posters, educational…

  1. Photograph of Earth taken from Apollo 13 spacecraft during transearth journey

    NASA Technical Reports Server (NTRS)

    1970-01-01

    This photograph of the Earth was taken from the Apollo 13 spacecraft during its transearth journey home. The most visible land mass includes southwestern United States and northwestern Mexico. The penisula of Baja California is clearly seen. Most of the land area is under heavy cloud cover.

  2. Journey to Becoming a Thai English Teacher: New Perspective on Investigating Teacher Attrition

    ERIC Educational Resources Information Center

    Prabjandee, Denchai

    2014-01-01

    In this study, the author provides a unique perspective on teacher shortage by focusing on teacher retention, in terms of why teachers stay in the teaching profession, rather than focusing on teacher attrition, or why teachers leave the teaching profession. The change in perspective created an opportunity to study the journey of how teachers chose…

  3. Historical Thinking inside the Box: Preservice Elementary Teachers Use Journey Boxes to Craft Counter Narratives

    ERIC Educational Resources Information Center

    Alarcon, Jeannette; Holmes, Kathlene; Bybee, Eric

    2015-01-01

    This article details the "journey box" project process enacted by two elementary preservice teacher cohorts. Engaging in activities and projects that promote a sense of investment in not only consuming but producing historical narratives, preservice teachers potentially become interested in sharing this type of learning with their…

  4. Latina University Professors, Insights into the Journeys of Those Who Strive to Leadership within Academia

    ERIC Educational Resources Information Center

    Vasquez-Guignard, Sandra Jeannette

    2010-01-01

    The statistics on Latinas who hold positions as professors and leaders in higher education are grim. Although there are more Latinas going to college, only 1% of professors in the U.S. are Latina. The purpose of this phenomenological study was to explore the lived experiences of 4 Latina professors to learn about their journeys to secure positions…

  5. Chelsea's Journey of Becoming a Teacher: A Narrative of Then and Now

    ERIC Educational Resources Information Center

    Blair, Deborah V.

    2013-01-01

    In this study I explored, with Chelsea, her journey of becoming a music teacher. At the time of the study, Chelsea had completed her second year of teaching. Together, we revisited the artifacts of her undergraduate coursework and practicum experiences (journals, online forum posts, videotapes of her own teaching, written reflections of her…

  6. A 2e Parent's Journey: Persistence, Partnership, and the Provision of Unconditional Love

    ERIC Educational Resources Information Center

    Brownstein, Michelle

    2015-01-01

    I have four children, three of whom are twice exceptional in the context of the new Community of Practice (2e CoP) definition highlighted in this issue. I share a personal story of a parent's journey in persistence, partnerships, and the provision of unconditional love.

  7. Student Journey Work: A Review of Academic Library Contributions to Student Transition and Success

    ERIC Educational Resources Information Center

    Weaver, Margaret

    2013-01-01

    This review aims to capture projects, services, and approaches that are being used to ensure student success and sustainability across the stages (or transitions) of the student experience of higher education, where these extend the traditional role of the library, in the UK and internationally. The article examines why the student journey (and…

  8. From the Mountains to the Sea: A Journey in Environmental Citizenship.

    ERIC Educational Resources Information Center

    Environment Canada, Ottawa (Ontario).

    This booklet is designed to help people make environmentally responsible decisions. This activity booklet is targeted at students as part of a learning campaign to help Canadians improve their understanding of the environment. The imaginary journey From the Mountains to the Sea is a trip along the Eco River following molecules of water from high…

  9. Formative Journeys of First-Year College Students: Tensions and Intersections with Intercultural Theory

    ERIC Educational Resources Information Center

    Shaw, Marta; Lee, Amy; Williams, Rhiannon

    2015-01-01

    Development of intercultural skills is recognized as an essential outcome of a college education, but in order to facilitate students' growth effectively, we must understand the points of the developmental journey at which students enter the college classroom. This study tests four hypotheses developed on the basis of leading models of…

  10. The Unexpected Journey: Renewing Our Commitment to Students through Educational Action Research

    ERIC Educational Resources Information Center

    Meyer, Helen; Hamilton, Bennyce; Kroeger, Steve; Stewart, Stephanie; Brydon-Miller, Mary

    2004-01-01

    This article presents four cases of journeys of discovery and renewal, and the unexpected learning that results from exploring our practice with others. The authors are three classroom teachers--Steve, Stephanie and Bennyce--all of whom took part in a year-long action research sequence and the two professors--Helen and Mary--who co-taught these…

  11. Plant Reproduction and the Pollen Tube Journey--How the Females Lure the Males

    ERIC Educational Resources Information Center

    Lorbiecke, Rene

    2012-01-01

    The growth of pollen tubes is one of the most characteristic events in angiosperm reproduction. This article describes an activity for visualizing the journey and guidance of pollen tubes in the reproductive structures of a flowering plant. The activity uses a semi-in vivo system with rapid-cycling "Brassica rapa," also known as Fast Plants.…

  12. Developing National Board Certified Teachers in North Carolina: A Journey from the Classroom to Leadership

    ERIC Educational Resources Information Center

    Bunch, Audrey Worrell

    2012-01-01

    This qualitative study examined a culture of teacher leadership that has evolved in North Carolina over the past 20 years, conveying the professional journey of teachers who had moved out of the classroom into other educational leadership roles after attainment of National Board for Professional Teaching Standards (NBPTS) certification. The study…

  13. When the Light Turns Blue: Journeying into Disability Studies Guided by the Work of Ellen Brantlinger

    ERIC Educational Resources Information Center

    Collins, Kathleen M.; Broderick, Alicia

    2013-01-01

    Ellen Brantlinger's research and activism created opportunities for scholars who seek to locate and interrupt the social processes that shape educational inequities. In this essay, we reflect on Ellen's contributions by identifying three key "signposts"--lessons from Ellen's work that guided our own journeys and shaped the…

  14. [Getting Ready for Our World Journey: Africa, Australia, and the Netherlands. 4th Grade.

    ERIC Educational Resources Information Center

    Nederland Independent School District, TX.

    GRADES OR AGES: Grade 4. SUBJECT MATTER: Social Studies; including units entitled "Getting Ready for Our World Journey,""Africa,""Australia," and "The Netherlands." ORGANIZATION AND PHYSICAL APPEARANCE: The guide is divided into four separately bound units. Each unit is further subdivided into lessons. The units are mimeographed and staple-bound.…

  15. A Personal Journey toward Culture-Centered Counseling: An Interview with Paul Pedersen

    ERIC Educational Resources Information Center

    Cartwright, Brenda Y.; D'Andrea, Michael

    2005-01-01

    Paul Pedersen's journey into becoming culturally competent has encountered interesting twists and turns. An introduction, a discussion of historical factors that help shape his life, a discussion of some of his major contributions, an assessment of the current state of multiculturalism, as well as Paul's vision of the future are all presented.

  16. Insights from Six Women on Their Personal Journeys to Becoming Deans of Agriculture: A Qualitative Study

    ERIC Educational Resources Information Center

    Kleihauer, Sarah; Stephens, Carrie Ann; Hart, William E.

    2012-01-01

    Understanding one's personal journey provides for effective learning, growth, and development (Madsen, 2010). Reflection on the influences and experiences of successful women leaders is essential to understanding the factors that have enabled them to obtain and sustain leadership positions in nontraditional career fields. The purpose of this…

  17. How To Avoid Crossfire and Seek Common Ground: A Journey for the Sake of Children.

    ERIC Educational Resources Information Center

    Ledell, Marjorie

    A democracy must tolerate many points of view without becoming divided. Therefore, public educators and the communities they serve are challenged to help students understand political and religious issues without proselytizing. This handbook provides guidelines for beginning the journey toward common ground, for moving from a climate of antagonism…

  18. Linking Action Learning and Inter-Organisational Learning: The Learning Journey Approach

    ERIC Educational Resources Information Center

    Schumacher, Thomas

    2015-01-01

    The article presents and illustrates the learning journey (LJ)--a new management development approach to inter-organisational learning based on observation, reflection and problem-solving. The LJ involves managers from different organisations and applies key concepts of action learning and systemic organisational development. Made up of…

  19. Female Superintendents: A Qualitative Study of the Journey to the Role of Superintendent

    ERIC Educational Resources Information Center

    Schmidt, Stacey M.

    2011-01-01

    This qualitative study examines the journey of females to the role of superintendent. This study is based on interviews of six female superintendents from Indiana and Illinois in cities with a population of 15,000 people or more. Three of the superintendents had more than 25 years of experience in education, and three of the superintendents had 25…

  20. The Road Less Traveled: A Superintendent's Journey from the Classroom to the District Office

    ERIC Educational Resources Information Center

    Jones, Sondra McCants

    2010-01-01

    The purpose of this qualitative case study was to document the leadership journey of one female superintendent who transformed the interface of a school district to create organizational change. The case study focused specifically on the leadership of Dr. Phyllis Wilson and the alignment of her leadership to the Educational Leadership Constituent…

  1. "There and Back Again": My Unexpected Journey into "Servant" and "Distributed" Leadership

    ERIC Educational Resources Information Center

    Youngs, Howard

    2007-01-01

    The journey that a practitioner takes into the realm of postgraduate research can be one that is sometimes filled with an unexpected cycle of security followed by doubt, and learning as a means of rediscovering a sense of security; there can be a continual sense of "coming back again" to familiar ground. This article is an autobiographical account…

  2. Action Research: A Personal Epiphany and Journey with Evidence-Based Practice

    ERIC Educational Resources Information Center

    Ballard, Susan D.

    2015-01-01

    The author reveals in this article that her action research journey in the land of evidence-based practice was not her own idea. She writes that she was lured by the profession's finest scholars who advocated for reflective dispositions for practitioners to improve their practice and demonstrate the school librarian's critical role in teaching and…

  3. Profiling Derald Wing Sue: Blazing the Trail for the Multicultural Journey and Social Justice in Counseling

    ERIC Educational Resources Information Center

    Romero, Dan; Chan, Anne

    2005-01-01

    This article reviews contributions of Derald Wing Sue to the counseling profession through his scholarship, teaching, leadership, and innovation in articulating multicultural issues in counseling.The article profiles Sue's multicultural journey by blending summaries from his writings, comments from professional colleagues, and information from a…

  4. Crossing the Digital Divide Safely and Trustingly: How Ecologies of Learning Scaffold the Journey

    ERIC Educational Resources Information Center

    Henning, Elizabeth; Van der Westhuizen, Duan

    2004-01-01

    The article addresses the issue of "learning to elearn" in borderless programs in a globalised learning landscape and the associated problems of scaffolding the journey across the digital divide. The authors argue that the assumption underlying such courses is that cross-cultural programs are viable because they are conceived and designed to be…

  5. Exploring the Issues of Incorporating Cultural Differences in Education: A Curriculum Journey in Playwriting

    ERIC Educational Resources Information Center

    Thom, Jennifer S.; Blades, David

    2014-01-01

    In response to a mandate to develop a more welcoming university for students, especially those of Aboriginal inheritance, we set out on a journey for ways of accommodating cultural differences in our university classrooms. Over the course of a year, we met regularly and audiotaped our conversations. By talking, transcribing, writing, and…

  6. Utopia, University and Architecture: A Journey that Changed the Design of Contemporary Universities

    ERIC Educational Resources Information Center

    Calvo-Sotelo, Pablo Campos

    2006-01-01

    In 1927, a group of advisors to King Alfonso XIII of Spain, led by the architect Modesto Lopez-Otero, set out for the United States and Canada. Previously, they had visited a number of European cities where they examined the medieval architectural form of some famous universities. Inspired by a Utopian vision, the journey to the New World studied…

  7. Immigrant Students at School: Easing the Journey towards Integration. OECD Reviews of Migrant Education

    ERIC Educational Resources Information Center

    OECD Publishing, 2015

    2015-01-01

    How school systems respond to immigration has an enormous impact on the economic and social well-being of all members of the communities they serve, whether they have an immigrant background or not. "Immigrant Students at School: Easing the Journey towards Integration" reveals some of the difficulties immigrant students encounter--and…

  8. The Arizona Journey Schools Program: A Strategy for Change. Final Report.

    ERIC Educational Resources Information Center

    Laughran, Laura J.; Shaw, Jerome M.

    The Arizona Journey Schools Program (JSP) was a two-year professional development experience whose stated purpose was to build the leadership capacity of school/community teams and establish a network of professionals to support teams as they bring about systemic change in mathematics and science teaching, learning, and assessment. This report…

  9. Learning Journeys: Student Experiences in Further and Higher Education in Scotland

    ERIC Educational Resources Information Center

    Higher Education Academy, 2013

    2013-01-01

    This research explores the factors that influence the "student journey" and the difficulties faced by some students in Scotland. Colleges and university undergraduates were surveyed, along with students on postgraduate-taught programmes in a joint partnership project between the HEA [Higher Education Academy] and NUS [National Union of…

  10. Learning Journeys: A Resource Handbook on Adult Learning and Mental Health.

    ERIC Educational Resources Information Center

    Mather, Joy; Atkinson, Sue

    This document explains how tutors and managers in adult education programs across the United Kingdom can smooth the journeys of adults with mental health difficulties who are returning to learning. The handbook begins with suggestions for its use and case studies of two adult learners with mental health difficulties. Sections 1 through 4 discuss…

  11. Journey to Library 2.0: One Library Trains Staff on the Social Tools Users Employ

    ERIC Educational Resources Information Center

    Hastings, Robin

    2007-01-01

    In December 2006, the Missouri River Regional Library (MRRL) in Jefferson City, embarked on a journey. They had been watching the Public Library of Charlotte-Mecklenburg County (PLCMC), NC, on its adventure through the wilds of Web 2.0, and they decided to follow the trail it had blazed. What PLCMC had done was pretty revolutionary. The library…

  12. Experiential Learning of History through Youth Journeys to Poland: Israeli Jewish Youth and the Holocaust

    ERIC Educational Resources Information Center

    Romi, Shlomo; Lev, Michal

    2007-01-01

    National history and collective memory and their impact on adolescents' knowledge and attitudes are the topic of this article. A follow-up study, it examines the long-term impact of a journey to historical monuments. Israeli Jewish high-school students have the option of experiential study, visiting cities and death camps in Poland. The first…

  13. A journey to continence: a case study of overactive bladder syndrome.

    PubMed

    Spilde, Nancy L

    2008-06-01

    Overactive bladder is a problem that many women experience and suffer with in silence for years. This is a case study about one such woman. Anna had problems with incontinence for more than five years when she sought treatment. This article presents the story of her journey and perseverance to achieve control of her bladder. PMID:18605514

  14. Red Earth, Brown Earth: Walking in Two Worlds, the Journey of Indigenous Women in Academia

    ERIC Educational Resources Information Center

    Herrera, Michelle D.

    2011-01-01

    This dissertation is both an autobiographical and collaborative exploration of the complexities experienced by Indigenous women in their academic journey. But more than that, the entire study was conducted in ways that are in accordance with Traditional Indigenous worldview, Indigenous Storytelling/Oral Tradition and the role of women in…

  15. Retracing the Journey: Teaching and Learning in an American High School

    ERIC Educational Resources Information Center

    Christenbury, Leila

    2007-01-01

    Leila Christenbury is well known as a writer and researcher in English Education: her classic book "Making the Journey," [ED437654] now in its third edition, has been a guide to countless middle and high school language arts teachers. In her new book, this veteran teacher and teacher educator reveals what did and---more surprisingly---did not…

  16. A Quality of Interrelating: Describing a Form of Meaningful Experience on a Wilderness River Journey

    ERIC Educational Resources Information Center

    Morse, Marcus

    2014-01-01

    In this paper I identify the components of "meaningful experiences" for participants on a wilderness river rafting journey. The research is phenomenologically informed, and includes interviews, journals, observations and follow-up emails from 32 participants on eight Franklin River (Tasmania) 10-day trips. It elicits individual…

  17. Being Alive to the Present: Perceiving Meaning on a Wilderness River Journey

    ERIC Educational Resources Information Center

    Morse, Marcus

    2015-01-01

    In an earlier paper I identified two key forms of "meaningful experience" for participants on a wilderness river rafting journey, namely a feeling of humility and being alive to the present. However, space considerations led me to describe only the first of these forms in any detail. In this paper I identify and describe the qualities of…

  18. From Wisconsin to Wyoming and Back Again: The Journey to a Bachelor's Degree and Teacher Licensure

    ERIC Educational Resources Information Center

    Finkel-Hoffman, Susan

    2016-01-01

    Susan Finkel-Hoffman, Ed.D. is the interim director of outreach for the Department of Special and Early Childhood Education at the University of Wisconsin-Oshkosh, and a coordinator for the Northern Arapaho Teacher Education Program. In this memior Finkel-Hoffman, recalls the journey of a group of teacher education students which began almost 10…

  19. A Personal Journey in Promoting Social Justice as a School Counselor: An Action Research Approach

    ERIC Educational Resources Information Center

    Dowden, Angel Riddick

    2010-01-01

    This article describes the author's journey as a school counselor utilizing an action research approach to advocate for social justice in education. Two case studies are provided to discuss the process utilized to advocate for equal education for all students as a school counselor. Lastly, the author reflects on the successes and failures…

  20. The Ed Tech Journey and a Future Driven by Disruptive Change

    ERIC Educational Resources Information Center

    Grush, Mary, Ed.

    2010-01-01

    In this article, the author talks about the education technology journey and a future driven by disruptive change. The author first provides a definition of disruptive change. To understand the potential for disruptive change in higher education--a disruption fueled by technology and related trends--the author begins with a look at the past and…

  1. My Voice Heard: The Journey of a Young Man with a Cerebral Visual Impairment

    ERIC Educational Resources Information Center

    Macintyre-Beon, Catriona; Mitchell, Kate; Gallagher, Ian; Cockburn, Debbie; Dutton, Gordon N.; Bowman, Richard

    2012-01-01

    This longitudinal case study presents John's journey through childhood and adolescence, living with visual difficulties associated with a cerebral visual impairment. It highlights the day-to-day problems that John encountered, giving practical solutions and strategies that have enabled his dream of going to a university to be realized. John and…

  2. Challenges to the Doctoral Journey: A Case of Female Doctoral Students from Ethiopia

    ERIC Educational Resources Information Center

    Bireda, Asamenew Demessie

    2015-01-01

    This study aimed to investigate some challenges female doctoral students experience in their doctoral journey. The study used a qualitative design and structured interviews. The theoretical framework that guided the study was that of Urie Bronfenbrenner's ecosystemic theory. A purposely selected sample of five female doctoral students from the…

  3. Journeying between the Education and Hospital Zones in a Collaborative Action Research Project

    ERIC Educational Resources Information Center

    Crow, Jayne; Smith, Lesley; Keenan, Iain

    2006-01-01

    The authors present their journey through the development of an action research project based on collaboration between university health lecturers and a practice development and research nurse in an NHS Trust hospital. The project was designed to raise awareness and improve the practice of all staff in relation to the dignity and respect shown to…

  4. Staff and Client Perspectives on the Journey Mapping Online Evaluation Tool in a Drug Court Program

    ERIC Educational Resources Information Center

    Crunkilton, Dhira D.

    2009-01-01

    The purpose of this study was to assess staff and client perspectives on the Internet-based Journey Mapping program evaluation tool. A drug court program was chosen for a case study research design. Six staff and 10 clients participated in interviews and observations, and also responded to a questionnaire. A staff survey provided additional data.…

  5. Gifted Homeschooling: Our Journey with a Square Peg. A Mother's Perspective

    ERIC Educational Resources Information Center

    Olmstead, Gwen

    2015-01-01

    The author shares that her journey with gifted homeschooling was filled with folly and a slow learning curve. By sharing some of the struggles and insights she faced, the author hopes others will benefit or find solace in knowing they are not alone when their square peg children do not fit into round holes. In this article the author discusses:…

  6. Smoke, Wind, and That Journey Upwards: Augustinian Reflections on the Role of Humility in Virtue Formation

    ERIC Educational Resources Information Center

    Herdt, Jennifer A.

    2015-01-01

    Augustine's training in pagan rhetoric, his classical education, and the productive tensions he experienced between pagan and Christian exemplars played a formative role in his spiritual journey. An examination of the generative aspects of these encounters with otherness yields insights for our own understanding, not just of the importance to…

  7. The Epistemological Differences between a Teacher and Researcher: A Personal Journey Illustrating Second Order Action Research

    ERIC Educational Resources Information Center

    Nicholl, Bill

    2009-01-01

    This keynote address tells the personal journey of a former teacher who is now involved in educational research. Educational research is topical at the moment in Design and Technology (D&T) Education, as many initial teacher training (ITE) courses make the transition to masters level accreditation, something endorsed by the teacher training and…

  8. Journey to the 'New Normal' and Beyond: Reflections on Learning in a Community of Practice

    ERIC Educational Resources Information Center

    Watson-Gegeo, Karen Ann

    2005-01-01

    Through poetry and strips of narrative, this paper discusses the embodied experience of chemical sensitivity and the anthropologist author's and other patients' journey through altered perception towards knowledge, community and transformation in the context of a medical clinic. The narratives are situated in several strands of relevant theory,…

  9. Women's journey of recovery from sexual assault trauma: a grounded theory--part 1.

    PubMed

    Duma, S E; Mekwa, J N; Denny, L D

    2007-12-01

    Thousands of women and children experience sexual assault trauma annually in South Africa. The challenge posed by recovery from sexual assault trauma is a reality that confronts the survivors of sexual assault, their families and the larger community of service providers. Yet, little research has been conducted on recovery from sexual assault as a phenomenon. The purpose of the study was to explore and analyse the journey of recovery which is undertaken by women who have been sexually assaulted, with the aim of discovering and developing the grounded theory of recovery from sexual assault trauma within the first six months following the event of rape. The main research question was: What constitutes the journey of recovery undertaken by women within the first six months following sexual assault? A longitudinal qualitative study was conducted using the principles of grounded theory methodology as proposed by Strauss and Corbin (1990, 1998). A series of in-depth one-to-one interviews were conducted with a sample of ten women. The participants were selected through open, purposive and theoretical sampling procedures. The study was conducted over a period of six months following the event of sexual assault. The substantive theory was discovered and constructed through the inductive and deductive analysis of data, grounded on the ten women's descriptions of their journey of recovery from sexual assault. The theory of women's journey of recovery that was discovered and developed consisted of eight theoretical concepts or categories. These included the following concepts: 1. Sexual assault trauma 2. Awakening 3. Pragmatic acceptance 4. Turning point 5. Reclaiming what was lost 6. Defining own landmarks of healing 7. Readiness for closure 8. Returning to self. The grounded theory of the journey of recovery from sexual assault is a contribution to the knowledge about women's journey of recovery from sexual assault. It provides a process and language for understanding women

  10. Extracting Models in Single Molecule Experiments

    NASA Astrophysics Data System (ADS)

    Presse, Steve

    2013-03-01

    Single molecule experiments can now monitor the journey of a protein from its assembly near a ribosome to its proteolytic demise. Ideally all single molecule data should be self-explanatory. However data originating from single molecule experiments is particularly challenging to interpret on account of fluctuations and noise at such small scales. Realistically, basic understanding comes from models carefully extracted from the noisy data. Statistical mechanics, and maximum entropy in particular, provide a powerful framework for accomplishing this task in a principled fashion. Here I will discuss our work in extracting conformational memory from single molecule force spectroscopy experiments on large biomolecules. One clear advantage of this method is that we let the data tend towards the correct model, we do not fit the data. I will show that the dynamical model of the single molecule dynamics which emerges from this analysis is often more textured and complex than could otherwise come from fitting the data to a pre-conceived model.

  11. BOOK REVIEW: A Journey with Fred Hoyle (Second Edition)

    NASA Astrophysics Data System (ADS)

    Wickramasinghe, Chandra; Sterken, Christiaan

    2013-12-01

    I read A Journey with Fred Hoyle: The Search for Cosmic Life shortly after the first edition appeared in 2005. The second expanded edition of this remarkable autobiographical account brings the scientific story up to date. The added Epilogue offers reflections in 2012, and shows that some of Hoyle's and Wickramasinghe's heretical theories have become accepted science today: these scientists were among the forerunners of today's astrobiology. The book is the story - presented as a blend of personal anecdotes, travel stories, references to political and social events, and science writing - of the remarkable 40-year friendship and scientific collaboration between the British astrophysicist Fred Hoyle and the Sri Lankan mathematician and astronomer Chandra Wickramasinghe. The author illuminates the story of his collaboration with Hoyle with interesting aspects of his personal life, such as the description of his educational background in Sri Lanka, and the story of how he, as a PhD student, made his first contact with his supervisor in 1960. The book also offers insights into Hoyle's and Wickramasinghe's family lives. The narrative also contains plenty of interstellar astrophysics along with the stories. Sir Fred Hoyle (1915-2001) was famous for his contribution to the theory of stellar nucleosynthesis, renowned for his coining (on BBC radio) of the term Big Bang and for his later rejection of that theory (coupled to his advocacy of the steady state cosmology), and famed as writer of more than a dozen science-fiction stories. He was the founding director of the Cambridge Institute of Theoretical Astronomy (that later became the Institute of Astronomy). Hoyle was a scientific whistleblower, a radical troublemaker, an unorthodox scientific mind, but also a victim of the system. Hoyle-Wickramasinghe thought was a long-term assault on conventional thinking: especially their notable concept of panspermia (that ever-present life pervades our universe) and their opposition to

  12. AB017. Interstitial lung disease patient diagnostic journey (intensity)

    PubMed Central

    Lederer, David J.; Bianchi, Pauline; Loboda, Jeanne; Danese, Sherry; Cosgrove, Gregory P.

    2016-01-01

    Background Interstitial lung disease (ILD) is complicated to diagnose because its signs and symptoms mimic a wide range of common medical conditions. The objective of the INTENSITY survey was to advance the understanding of respondents’ diagnostic experiences with ILDs, including idiopathic pulmonary fibrosis (IPF). The survey was designed to trace the path that respondents took to diagnosis, identify obstacles they faced, and gauge the emotional impact of their journey. Results from the INTENSITY survey will help us more fully understand respondents’ diagnostic experiences so we can further our efforts to improve timely diagnosis and treatment of ILDs. Methods We administered a 25-minute quantitative online survey from August 14–26, 2015. Of the 1,152 respondents screened to ensure they were US residents, and had been diagnosed with an interstitial lung disease, 600 met criteria and completed the survey. Recruitment was accomplished through two channels: email invitations sent to 16,000 Pulmonary Fibrosis Foundation (PFF) members and an open invitation to participate through the pulmonary fibrosis community website Results Shortness of breath (77%) and cough (53%) were the most common early symptoms in ILD patients. Twenty-five percent of respondents saw their primary care physician once before being referred to a specialist, however 61% of respondents saw their primary care physician >2 times before referral to a pulmonologist. Misdiagnosis occurred in 55% of respondents. The median time from symptom onset to correct diagnosis was 11 months, however 49% of respondents carried an incorrect diagnosis for 1 to 10 years. Thirty-eight percent were misdiagnosed more than twice, most frequently with asthma, pneumonia, bronchitis, and allergies. An accurate diagnosis was achieved after a median of 6 months and a median of 3 physician visits. The majority underwent an invasive diagnostic procedure. Fourteen percent of respondents saw more than 6 physicians before

  13. AIDS: responding to the crisis. Pastoral care: helping patients on an inward journey.

    PubMed

    Tibesar, L J

    1986-05-01

    AIDS is unique in that it is terminal, transmissible, and surrounded by stigma. AIDS patients are often ostracized by those close to them and frequently they are alienated from religion. The pastoral care giver must provide a special ministry to AIDS patients, a ministry in which he or she accompanies the patient on a journey inward. This journey involves a broad range of feelings related to such concerns as social alienation, emotional isolation, and preparation for death. Its final destination, however, lies in the ultimate issues such as self-identity, the meaning of life, and individual destiny. To help the patient confront these issues, the pastoral care giver may first have to break through negative images held by many alienated persons with AIDS. These include the image of God as judge; the image of the Catholic minister as a celibate upholder of a rigid sexual code; and the perception that spirituality is the special preserve of "religious" persons. PMID:10276809

  14. The Importance of the Partner: Supporting Nurse Leaders' Journey to Executive Roles.

    PubMed

    Blouin, Ann Scott

    2015-01-01

    Having a fully committed partner is an asset some nurse executives celebrate. The life partner can play a critical role in the nurse executive's career from a personal perspective. The importance of being flexible and balancing "who does what" and how to manage through life's challenges is reported through three nurse executives' stories and one spouse. Having a partner enriches the life journey, according to these leaders. PMID:26477122

  15. The Charles F. Prentice Award Lecture 2014: A 50-Year Research Journey: Giants and Great Collaborators.

    PubMed

    Holden, Brien A

    2015-07-01

    This article, an edited version of the 2014 Charles F. Prentice Medal presentation, recounts my 50-year journey in research, from graduation in 1965 to PhD to 2015. The most important lessons I have learned are that great people, "Giants" as I call them, are generous of spirit, creative, insightful, sharing, and caring, and second, that collaboration is really the only way to do what I want to get done. I have been very fortunate to have worked with many outstanding people. As someone said to me at the Prentice Medal presentation, "I don't like you very much but the people you work with are wonderful."My journey started with a PhD investigation into seeing if orthokeratology could control myopia at the City University London in 1966. It then moved to Australia where all aspects of contact lenses were researched to try to make contact lenses safer and more effective by understanding the cornea and anterior eye systems. That journey has now turned to making contact lenses the best they can be to slow the progress of myopia. An extremely high proportion of people who are involved with global eye care initiatives and ambitious projects to develop treatments and interventions for the major vision problems impacting the world are a joy to work with. Evidence-based systems for delivering vision to the more than 600 million people globally that are blind or vision impaired because of uncorrected refractive error have involved amazing people and collaborations. This article pays tribute to the generosity and humanity of my family and the Giants in and outside the field, and many more not so well known, and the people I work with, who have punctuated and greatly enriched this journey and made many of the scientific advances documented here possible. PMID:26002010

  16. Carbon footprint of patient journeys through primary care: a mixed methods approach

    PubMed Central

    Andrews, Elizabeth; Pearson, David; Kelly, Charlotte; Stroud, Laura; Rivas Perez, Martin

    2013-01-01

    Background The NHS has a target of cutting its carbon dioxide (CO2) emissions by 80% below 1990 levels by 2050. Travel comprises 17% of the NHS carbon footprint. This carbon footprint represents the total CO2 emissions caused directly or indirectly by the NHS. Patient journeys have previously been planned largely without regard to the environmental impact. The potential contribution of ‘avoidable’ journeys in primary care is significant. Aim To investigate the carbon footprint of patients travelling to and from a general practice surgery, the issues involved, and potential solutions for reducing patient travel. Design and setting A mixed methods study in a medium-sized practice in Yorkshire. Method During March 2012, 306 patients completed a travel survey. GIS maps of patients’ travel (modes and distances) were produced. Two focus groups (12 clinical and 13 non-clinical staff) were recorded, transcribed, and analysed using a thematic framework approach. Results The majority (61%) of patient journeys to and from the surgery were made by car or taxi; main reasons cited were ‘convenience’, ‘time saving’, and ‘no alternative’ for accessing the surgery. Using distances calculated via ArcGIS, the annual estimated CO2 equivalent carbon emissions for the practice totalled approximately 63 tonnes. Predominant themes from interviews related to issues with systems for booking appointments and repeat prescriptions; alternative travel modes; delivering health care; and solutions to reducing travel. Conclusion The modes and distances of patient travel can be accurately determined and allow appropriate carbon emission calculations for GP practices. Although challenging, there is scope for identifying potential solutions (for example, modifying administration systems and promoting walking) to reduce ‘avoidable’ journeys and cut carbon emissions while maintaining access to health care. PMID:23998839

  17. The college journey and academic engagement: how metaphor use enhances identity-based motivation.

    PubMed

    Landau, Mark J; Oyserman, Daphna; Keefer, Lucas A; Smith, George C

    2014-05-01

    People commonly talk about goals metaphorically as destinations on physical paths extending into the future or as contained in future periods. Does metaphor use have consequences for people's motivation to engage in goal-directed action? Three experiments examine the effect of metaphor use on students' engagement with their academic possible identity: their image of themselves as academically successful graduates. Students primed to frame their academic possible identity using the goal-as-journey metaphor reported stronger academic intention, and displayed increased effort on academic tasks, compared to students primed with a nonacademic possible identity, a different metaphoric framing (goal-as-contained-entity), and past academic achievements (Studies 1-2). This motivating effect persisted up to a week later as reflected in final exam performance (Study 3). Four experiments examine the cognitive processes underlying this effect. Conceptual metaphor theory posits that an accessible metaphor transfers knowledge between dissimilar concepts. As predicted in this paradigm, a journey-metaphoric framing of a possible academic identity transferred confidence in the procedure, or action sequence, required to attain that possible identity, which in turn led participants to perceive that possible identity as more connected to their current identity (Study 4). Drawing on identity-based motivation theory, we hypothesized that strengthened current/possible identity connection would mediate the journey framing's motivating effect. This mediational process predicted students' academic engagement (Study 5) and an online sample's engagement with possible identities in other domains (Study 6). Also as predicted, journey framing increased academic engagement particularly among students reporting a weak connection to their academic possible identity (Study 7). PMID:24749818

  18. An Evaluation of Understandability of Patient Journey Models in Mental Health

    PubMed Central

    2016-01-01

    Background There is a significant trend toward implementing health information technology to reduce administrative costs and improve patient care. Unfortunately, little awareness exists of the challenges of integrating information systems with existing clinical practice. The systematic integration of clinical processes with information system and health information technology can benefit the patients, staff, and the delivery of care. Objectives This paper presents a comparison of the degree of understandability of patient journey models. In particular, the authors demonstrate the value of a relatively new patient journey modeling technique called the Patient Journey Modeling Architecture (PaJMa) when compared with traditional manufacturing based process modeling tools. The paper also presents results from a small pilot case study that compared the usability of 5 modeling approaches in a mental health care environment. Method Five business process modeling techniques were used to represent a selected patient journey. A mix of both qualitative and quantitative methods was used to evaluate these models. Techniques included a focus group and survey to measure usability of the various models. Results The preliminary evaluation of the usability of the 5 modeling techniques has shown increased staff understanding of the representation of their processes and activities when presented with the models. Improved individual role identification throughout the models was also observed. The extended version of the PaJMa methodology provided the most clarity of information flows for clinicians. Conclusions The extended version of PaJMa provided a significant improvement in the ease of interpretation for clinicians and increased the engagement with the modeling process. The use of color and its effectiveness in distinguishing the representation of roles was a key feature of the framework not present in other modeling approaches. Future research should focus on extending the pilot

  19. Integrated travel network model for studying epidemics: Interplay between journeys and epidemic

    PubMed Central

    Ruan, Zhongyuan; Wang, Chaoqing; Ming Hui, Pak; Liu, Zonghua

    2015-01-01

    The ease of travelling between cities has contributed much to globalization. Yet, it poses a threat on epidemic outbreaks. It is of great importance for network science and health control to understand the impact of frequent journeys on epidemics. We stress that a new framework of modelling that takes a traveller’s viewpoint is needed. Such integrated travel network (ITN) model should incorporate the diversity among links as dictated by the distances between cities and different speeds of different modes of transportation, diversity among nodes as dictated by the population and the ease of travelling due to infrastructures and economic development of a city, and round-trip journeys to targeted destinations via the paths of shortest travel times typical of human journeys. An example is constructed for 116 cities in China with populations over one million that are connected by high-speed train services and highways. Epidemic spread on the constructed network is studied. It is revealed both numerically and theoretically that the traveling speed and frequency are important factors of epidemic spreading. Depending on the infection rate, increasing the traveling speed would result in either an enhanced or suppressed epidemic, while increasing the traveling frequency enhances the epidemic spreading. PMID:26073191

  20. Journeys to health services in Great Britain: an analysis of changing travel patterns 1985-2006.

    PubMed

    Hine, Julian; Kamruzzaman, Md

    2012-03-01

    This paper examines changing patterns in the utilisation and geographic access to health services in Great Britain using National Travel Survey data (1985-2006). The utilisation rate was derived using the proportion of journeys made to access health services. Geographic access was analysed by separating the concept into its accessibility and mobility dimensions. Regression analyses were conducted to investigate the differences between different socio-spatial groups in these indicators over the period 1985-2006. This study found that journey distances to health facilities were significantly shorter and also gradually reduced over the period in question for Londoners, females, those without a car or on low incomes, and older people. However, most of their rates of utilisation of health services were found to be significantly lower because their journey times were significantly longer and also gradually increased over the periods. These findings indicate that the rate of utilisation of health services largely depends on mobility level although previous research studies have traditionally overlooked the mobility dimension. PMID:22014623

  1. Integrated travel network model for studying epidemics: Interplay between journeys and epidemic

    NASA Astrophysics Data System (ADS)

    Ruan, Zhongyuan; Wang, Chaoqing; Ming Hui, Pak; Liu, Zonghua

    2015-06-01

    The ease of travelling between cities has contributed much to globalization. Yet, it poses a threat on epidemic outbreaks. It is of great importance for network science and health control to understand the impact of frequent journeys on epidemics. We stress that a new framework of modelling that takes a traveller’s viewpoint is needed. Such integrated travel network (ITN) model should incorporate the diversity among links as dictated by the distances between cities and different speeds of different modes of transportation, diversity among nodes as dictated by the population and the ease of travelling due to infrastructures and economic development of a city, and round-trip journeys to targeted destinations via the paths of shortest travel times typical of human journeys. An example is constructed for 116 cities in China with populations over one million that are connected by high-speed train services and highways. Epidemic spread on the constructed network is studied. It is revealed both numerically and theoretically that the traveling speed and frequency are important factors of epidemic spreading. Depending on the infection rate, increasing the traveling speed would result in either an enhanced or suppressed epidemic, while increasing the traveling frequency enhances the epidemic spreading.

  2. Utility of passive photography to objectively audit built environment features of active transport journeys: an observational study

    PubMed Central

    2013-01-01

    Background Active transport can contribute to physical activity accumulation and improved health in adults. The built environment is an established associate of active transport behaviours; however, assessment of environmental features encountered during journeys remains challenging. The purpose of this study was to examine the utility of wearable cameras to objectively audit and quantify environmental features along work-related walking and cycling routes. Methods A convenience sample of employed adults was recruited in New Zealand, in June 2011. Participants wore a SenseCam for all journeys over three weekdays and completed travel diaries and demographic questionnaires. SenseCam images for work-related active transport journeys were coded for presence of environmental features hypothesised to be related to active transport. Differences in presence of features by transport mode and in participant-reported and SenseCam-derived journey duration were determined using two-sample tests of proportion and an independent samples t-test, respectively. Results Fifteen adults participated in the study, yielding 1749 SenseCam images from 30 work-related active transport journeys for coding. Significant differences in presence of features were found between walking and cycling journeys. Almost a quarter of images were uncodeable due to being too dark to determine features. There was a non-significant tendency for respondents to under-report their journey duration. Conclusion This study provides proof of concept for the use of the SenseCam to capture built environment data in real time that may be related to active transportation. Further work is required to test and refine coding methodologies across a range of settings, travel behaviours, and demographic groups. PMID:23575288

  3. 77 FR 76809 - Submission of Itineraries

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-31

    ... recordkeeping. On October 1, 2009, we published in the Federal Register (74 FR 50738-50740, Docket No. APHIS... time to time shall notify AC when any animal is gone more than four (4) consecutive days. Upon request... existing Agency policy when a regulated animal is exhibited away from its approved site for 4 days or...

  4. Clinical pathology services: remapping our strategic itinerary.

    PubMed

    Blanckaert, Norbert

    2010-07-01

    Both technological advances and economic drivers have led to major changes in clinical laboratories across the world, with vastly improved testing productivity. However, the production process capability advances have far outpaced the clinical pathologists' success in assuring optimal test utilization and interpretation. While productivity of 'commodity' testing increases, our healthcare value productivity decreases. Such developments constitute a serious threat to our clinical pathology specialty, not only because pathologists may lose direct control of the commodity testing production activities, but also because the present evolution exposes a failure of our core clinical activities, the pathologist's knowledge processes that translate 'commodity' results into medical outcomes optimization. At a time when a revolution in health care organization is inescapable in the years ahead, clinical pathology must proceed from a merely reactive strategy (to fulfill the 'more with less' demands) to a proactive strategy where we build excellence and visibility in knowledge services on a strong foothold of operational excellence. Based on a Strengths-Weaknesses-Opportunities-Threats analysis, we argue that clinical pathology should safeguard and expand its healthcare value productivity by assuming leadership in building integrated laboratory services networks. We also suggest that the core knowledge processes deserve a system approach, for example, by applying a risk-based quality management system. PMID:20491600

  5. Itineraries of Identity in Undergraduate Science

    ERIC Educational Resources Information Center

    Bucholtz, Mary; Barnwell, Brendan; Skapoulli, Elena; Lee, Jung-Eun Janie

    2012-01-01

    Building on recent linguistic-anthropological work that investigates the temporalities of educational processes, the article examines how a marginalized classroom identity is interactionally formed over time in an undergraduate chemistry laboratory. The analysis demonstrates how social marginalization is enacted along multiple temporal scales via…

  6. Meeting the Mentor: The Role of the Teacher-Director in Engineering a Hero's Journey for Participants in an Educational Drama Workshop Series

    ERIC Educational Resources Information Center

    Van Vuuren, Petro Janse

    2004-01-01

    This paper will make a critical comparison between the stages of the Hero's Journey as presented by Christopher Vogler and the taxonomy of personal engagement as articulated by Educational Drama theorists. Both Vogler's journey and the taxonomy describe how a person travels from one world into another and back again, combining the two results in a…

  7. MLC Libraries--A School Library's Journey with Students, Staff and Web 2.0 Technologies: Blogs, Wikis and E-Books--Where Are We Going Next?

    ERIC Educational Resources Information Center

    Viner, Jane; Lucas, Amanda; Ricchini, Tracey; Ri, Regina

    2010-01-01

    This workshop paper explores the Web 2.0 journey of the MLC Libraries' teacher-librarians, librarian, library and audio visual technicians. Our journey was initially inspired by Will Richardson and supported by the School Library Association of Victoria (SLAV) Web 2.0 professional development program. The 12 week technological skills program "23…

  8. New data on Jean-Étienne Guettard's journey to Poland in the years 1760-1762

    NASA Astrophysics Data System (ADS)

    Tarkowski, Radosław

    2004-10-01

    This paper presents new information on the journey of the French geologist Jean-Étienne Guettard to Poland in the years 1760-1762. Search in the Archives of the Academy of Sciences in Paris, especially a review of his biographic dossier and collections of documents reports delivered at the meetings of the Academy, made it possible to find rich material (letters, reports, notes from field studies, drafts of lectures and others), a large part of which refers to this journey. This hitherto overlooked material well supplements our knowledge of the journey and casts some new light on the scope and extent and results of geological and meteorological studies carried out by J.-É. Guettard during his stay in Poland. To cite this article: R. Tarkowski, C. R. Geoscience 336 (2004).

  9. The Pilgram's Progress: Reflections on the journey building Australia's solid earth information infrastructure (Invited)

    NASA Astrophysics Data System (ADS)

    Woodcock, R.

    2013-12-01

    Australia's AuScope provides world class research infrastructure as a framework for understanding the structure and evolution of the Australian continent. Since it conception in 2005, Data Scientists have led the Grid and Interoperability component of AuScope. The AuScope Grid is responsible for the effective management, curation, preservation and analysis of earth science data across the many organisations collaborating in AuScope. During this journey much was learned about technology and architectures but even more about organisations and people, and the role of Data Scientists in the science ecosystem. With the AuScope Grid now in operation and resulting techniques and technologies now underpinning Australian Government initiatives in solid earth and environmental information, it is beneficial to reflect upon the journey and observe what has been learned in order to make data science routine. The role of the Data Scientist is a hybrid one, of not quite belonging and yet highly valued. With the skills to support domain scientists with data and computational needs and communicate across domains, yet not quite able to do the domain science itself. A bridge between two worlds, there is tremendous satisfaction from a job well done, but paradoxically it is also best when it is unnoticeable. In the years since AuScope started much has changed for the Data Scientist. Initially misunderstood, Data Scientists are now a recognisable part of the science landscape in Australia. Whilst the rewards and incentives are still catching up, there is wealth of knowledge on the technical and soft skills required and recognition of the need for Data Scientists. These will be shared from the AuScope journey so other pilgrims may progress well.

  10. THE USE AND ABUSE OF OMNIPOTENCE IN THE JOURNEY OF THE HERO.

    PubMed

    Steiner, John

    2015-07-01

    The author uses Joseph Campbell's (1949) account of the "Journey of the Hero" to examine a sequence of stages in which the hero must first use omnipotence in order to embark on an adventure, and then relinquish it in order to return to the ordinary world. The author detects parallels to this theme in descriptions of the fate of Lucifer in Milton's Paradise Lost (1674), and in the development of toddlers as described in Mahler's (1972) observations on separation-individuation. Finally, he traces a similar process in clinical material drawn from near the end of a patient's analysis. PMID:26198606

  11. A Dozen Strategies Along the Ten Steps Baby-Friendly Initiative Journey.

    PubMed

    Salvador, Ann; Dumas, Louise; Davies, Barbara; Emard, Marie-Josée; Lortie, Kim

    2016-01-01

    To improve the quality of care and maternal-newborn outcomes, Hôpital Montfort implemented the Registered Nurses' Association of Ontario Best Practice Guideline on Breastfeeding, which supports the Baby-Friendly Initiative (BFI). This journey was challenging yet rewarding. Overall, we report success with increased mother-infant skin-to-skin contact at birth and breastfeeding immediately postpartum. However, challenges with formula supplementation rates continue. This paper discusses 12 strategies that emerged from lessons learned and provides links to our policies and patient education materials. The information may be helpful to others, as implementation of parts of the BFI are inserted in criteria for the Canadian accreditation. PMID:27009713

  12. Journey of change and back: a case study of a reconstituted social work service.

    PubMed

    Alvelo, Jaime; Garcia, Jerika; Rosario, David

    2008-01-01

    As a result of Total Quality Management and Reengineering principles during the VA's "Journey of Change" in the mid-1990s many hospital social work departments were re-organized under umbrella-care lines. Outcome studies of this movement have focused primarily on patient services. This study focused on the service providers' (including social workers) point of view and their satisfaction with the change in service structure. Data gathering consisted of a master thesis project by one of the co-authors, an administrative in-house survey of staff satisfaction, a qualitative presentation of staff concerns, and the perspective of the administrator who took the decision. PMID:18956511

  13. STS-30 Magellan spacecraft arrives at KSC after six-day journey from Colorado

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The Payload Environmental Transportation System (PETS) (semi-truck and trailer), which transported the Magellan spacecraft on its six-day journey from Martin Marietta in Denver, Colorado, to Kennedy Space Center (KSC), arrives safely at the Space Assembly and Encapsulation Facility 2 (SAEF-2) planetary checkout facility. The spacecraft, destined for unprecedented studies of Venusian topographic features, is to be deployed by the crew of NASA's STS-30 mission in April 1989. View provided by KSC with alternate number KSC-88PC-1082.

  14. Rotavirus Entry: a Deep Journey into the Cell with Several Exits

    PubMed Central

    Silva-Ayala, Daniela; López, Susana

    2014-01-01

    Rotaviruses are the leading etiological agents of acute gastroenteritis in infants and young children worldwide. These nonenveloped viruses enter cells using different types of endocytosis and, depending on the virus strain, travel to different endosomal compartments before exiting to the cytosolic space. In this Gem, we review the viral and cellular factors involved in the different stages of a productive virus cell entry and share with the readers the journey that we have taken into the cell to learn about virus entry. PMID:25378490

  15. Speaking of privilege: family therapy educators' journeys toward awareness and compassionate action.

    PubMed

    Hernandez-Wolfe, Pilar; McDowell, Teresa

    2012-06-01

    This study explores how family therapy educators from privileged social locations understand issues of privilege and the process by which they integrate their personal and professional journeys to create and model equity in family therapy training and professional development. These educators developed awareness about issues of privilege and oppression and owned their privilege. Increased awareness involved personal struggles with guilt and managing internalized voices of prejudice that are constantly reinforced in society. These educators adopted a stance of action and accountability for equity. We hypothesize that the process leading to owning one's privilege involves the ability to be compassionate for others' suffering and one's own limitations. PMID:22690858

  16. The sociology of childbirth: an autobiographical journey through four decades of research.

    PubMed

    Oakley, Ann

    2016-06-01

    The sociology of childbirth emerged in the 1970s largely as a result of influences from outside sociology. These included feminism, maternity care activism, the increasing medicalisation of childbirth, and evidence-based health care. This paper uses the author's own sociological 'career' to map a journey through four decades of childbirth research. It demonstrates the importance of social networks and interdisciplinary work, particularly across the medical-social science divide and including cross-cultural perspectives, argues that the study of reproduction has facilitated methodological development within the social sciences, and suggests that childbirth remains on the periphery of mainstream sociological concerns. PMID:26857343

  17. A Four-Year Hospital Journey for a Lost and Migrating Appendicolith

    PubMed Central

    Schraffl, Daniel; Frima, Herman; Villiger, P.

    2015-01-01

    We report a rare case of recurrent abscess formation, including being at a retroperitoneal site, due to a lost and migrating appendicolith. Over a four-year period and following an episode of perforated appendicitis, an otherwise healthy young man underwent two operations for abscess formation with eventual stone removal. Appendicoliths can pose a challenge during the diagnostic and therapeutic journey, and adequate attempts at removal need to be made to prevent avoidable complications. In patients suffering from recurrent flank pain and abscesses after appendectomy, the possibility of a lost or overlooked appendicolith should be considered. PMID:26345113

  18. 'Journeys' in the life-writing of adult-child dementia caregivers.

    PubMed

    Zimmermann, Martina

    2013-09-01

    This article explores how Alzheimer's disease caregivers struggle under the impact of a parent's memory loss on their own personality. In particular, it analyses how caregivers perceive and, thus, present their experiences of the ever intensifying caregiving activity in terms of a 'journey'. In doing so, this work takes into account both the patient's continuing bodily as well as cognitive decline and its intricately linked influence on the caregiver's physical and emotional stability. Equally, this study investigates how caregivers portray memory loss, and how their portrayal fits into our conceptualisation of illness narratives and the culture of autobiographical writing. PMID:23728880

  19. A three-decade-long journey at the College of Optical Sciences

    NASA Astrophysics Data System (ADS)

    Sarid, Dror

    2014-09-01

    In 1980, Peter Franken, the second director of the Optical Sciences Center, recruited an international quartet of faculty members from the US, Canada, England and Israel (DS). Peter shaped the Center as a clockwork operation, nailing down every aspect of its administration, business model and academic vision. I found myself from day one in a highly competitive environment with extreme peer pressure to make good science and generate a lot of funds. This paper describes the academic journey through my three decades at the Optical Sciences Center that became the College of Optical Sciences (Optical Sciences, in short) until my retirement in 2010, by highlighting selected areas of my group's research.

  20. Secondary health conditions and spinal cord injury: an uphill battle in the journey of care

    PubMed Central

    2013-01-01

    Purpose To understand the journey of care in the prevention and management of secondary health conditions (SHCs) following spinal cord injury (SCI). Method This was a case study design with ‘Ontario’ as the case. The Network Episode Model was used as the conceptual framework. Data sources included in depth interviews with persons with SCI, care providers, and policy and decision makers. Document analysis was also conducted on relevant materials and policies. Key informants were selected by purposeful sampling as well as snowball sampling to provide maximum variation. Data analysis was an iterative process and involved descriptive and interpretive analyses. A coding structure was developed based on the conceptual framework which allowed for free nodes when emerging ideas or themes were identified. Results Twenty-eight individuals were interviewed (14 persons with SCI and 14 persons representing care providers, community advocacy organization representatives, system service delivery administrators and policy-makers). A major over-arching domain that emerged from the data was the concept of ‘fighting’. Eleven themes were identified: at the micro-individual level: (i) social isolation and system abandonment, (ii) funding and equitable care, (iii) bounded freedom and self-management; at the meso care provider level: (iv) gender and caregiving strain, (v) help versus disempowerment, (vi) holistic care-thinking outside the box, (vii) poor communication and coordination of care; and at the macro health system level: (viii) fight for access and availability, (ix) models of care tensions, (x) private versus public tensions and (xi) rigid rules and policies. Conclusions Findings suggest that the journey is challenging and a persistent uphill struggle for persons with SCI, care providers, and community-based advocates. If we are to make significant gains in minimizing the incidence and severity of SHCs, we need to tailor efforts at the health system level. Implications

  1. 3D single molecule tracking in thick cellular specimens using multifocal plane microscopy

    NASA Astrophysics Data System (ADS)

    Ram, Sripad; Ward, E. Sally; Ober, Raimund J.

    2011-03-01

    One of the major challenges in single molecule microscopy concerns 3D tracking of single molecules in cellular specimens. This has been a major impediment to study many fundamental cellular processes, such as protein transport across thick cellular specimens (e.g. a cell-monolayer). Here we show that multifocal plane microscopy (MUM), an imaging modality developed by our group, provides the much needed solution to this longstanding problem. While MUM was previously used for 3D single molecule tracking at shallow depths (~ 1 micron) in live-cells, the question arises if MUM can also live up to the significant challenge of tracking single molecules in thick samples. Here by substantially expanding the capabilities of MUM, we demonstrate 3D tracking of quantum-dot labeled molecules in a ~ 10 micron thick cell monolayer. In this way we have reconstructed the complete 3D intracellular trafficking itinerary of single molecules at high spatial and temporal precision in a thick cell-sample. Funding support: NIH and the National MS Society.

  2. Spiritual Journey in Mothers’ Lived Experiences of Caring for Children With Autism Spectrum Disorders

    PubMed Central

    Heydari, Abbas; Shahidi, Laleh Hosseini; Mohammadpour, Ali

    2015-01-01

    Introduction: Helping mothers who have children with autism spectrum disorders requires understanding of their lived experiences. This study aims to uncover the spiritual journey as a main theme in Iranian mothers’ experiences. Method: This hermeneutic phenomenological study is a part of a larger study undertaken for partial fulfillment of the requirement for PhD dissertation in nursing. The main study was performed on 18 cases of Iranian mothers, with experience of caring for a child with an autism spectrum during 2011-2012. They were selected based on purposeful sampling method. Semi -structured interviews for data collection were used. Data analyses were done with the interpretative method. Results: Spiritual journey is one of the main themes of the phenomenon under study in the original project. It consists of three sub -themes each of which supported by a number of common meaning. The sub-themes and their common meanings in parenthesis are (1) Descent: wondering between what is and what will be (having sorrowful tale, unanswered question, escaping from reality, losing hope) (2) Connecting to deity: reflection on the failure in her struggle (gratefulness, surrendering to god, having the divine test) (3) Ascent: helping her child is becoming all of the mother’s life (to rescue, being hopeful, listening to her inner voice). Conclusion: This research concluded that caring for the autistic children led mothers’ lives to raise spirituality and enabled them to help their children and themselves, to grow and be refined in this process. PMID:26153169

  3. The life of Eugene Braunwald: a remarkable journey that began in Vienna.

    PubMed

    Schlossmacher, M G

    1998-01-16

    The life of Dr. Eugene Braunwald, who is without doubt the preeminent cardiologist of our time, represents a remarkable journey that began in Vienna, Austria. It took an early and decisive turn in July 1938 when his family was forced into exile by Austrian Nazism, ultimately settling in the United States. During his career Dr. Braunwald has provided unprecedented contributions to the theory and practice of medicine, foremost in cardiovascular research and clinical cardiology. Professionally, his pursuit of excellence continues in the roles of physician-scientist, academic teacher, editor and administrator. Personally, Dr. Braunwald's voyage came full circle in the summer of 1995, some fifty seven years after his emigration, when the University of Vienna awarded him an honorary Medical Doctorate. This article reviews Dr. Eugene Braunwald's remarkable journey from his childhood in pre-World War II Vienna to the current titles of Distinguished Hersey Professor of Medicine and Faculty Dean for Academic Programs at Harvard Medical School and Vice President of Partner's HealthCare Systems in Boston, Massachusetts. This essay is also intended to raise awareness of, and foster academic investigation into, the long-lasting implications of Austrian Nazism on the "Viennese School of Medicine". PMID:9499476

  4. Exploring parents' understandings of their child's journey into offending behaviours: A narrative analysis.

    PubMed

    Knowles, Susan Frances; Eccles, Fiona Jr; Daiches, Anna; Bowers, Mark

    2016-07-01

    Parents are perhaps the best placed individuals to comment upon their child's life story, including early life experiences, transitions and their child's needs. However, research has rarely focussed on the views of parents of young people who have committed serious offences. This research aimed to explore parents' opinions of which factors may have led to their child becoming involved with the criminal justice system. Interviews were undertaken with six parents who were asked to narrate their child's life journey into offending behaviours. The data were then analysed using narrative analysis techniques, and a shared story was created which incorporated the main transitional stages in the children's journeys, as seen by the parents. The findings suggest that it is not just the child but the whole family who have been in a state of distress throughout the child's life. Systemic and environmental factors are argued to contribute to this distress, and the use of diagnosis for this population is critically evaluated. The research highlights a life story in which the child's and family's distress remains unheard and therefore unresolved. Clinical implications for working with this population are discussed. PMID:26585068

  5. Journey to become a nurse leader mentor: past, present and future influences.

    PubMed

    McCloughen, Andrea; O'Brien, Louise; Jackson, Debra

    2014-12-01

    Mentorship, often viewed as a central capacity of leadership, is acknowledged as influential in growing nurse leaders. Mentoring relationships are perceived as empowering connections offering a dynamic guided experience to promote growth and development in personal and professional life. A hermeneutic phenomenological approach informed by Heidegger and Gadamer was used to explore understandings and experiences of mentorship for nurse leadership by 13 Australian nurse leaders. We found that learning and transformation associated with becoming a nurse leader mentor was experienced as an enduring evolutionary process. Participants' life journeys provided experiences that developed their understandings and established their personal identity as a leader and mentor. We considered the journey motif in terms of its inextricable connection with lived time and used Heidegger's ecstasies of temporality as a lens to understand how the temporal dimensions of past, present and future influenced and shaped the development of nurse leader mentors. We found that our temporal existence influences interpretation of ourselves and the world. Individuals can benefit from multiple separate mentoring interludes, with different mentors, over a lifetime. For some nurses, becoming a leader and mentor is a lifelong transformative process that grows from diverse experience and influential role modelling rather than formal instruction. PMID:24372852

  6. The journey beyond silos. Teaching and learning interprofessional ethics at UTHealth.

    PubMed

    Flaitz, Catherine M; Carlin, Nathan; Shepherd, Boyd W; McWherter, Jayne A; Bebermeyer, Richard D; Walji, Muhammad F; Spike, Jeffrey

    2011-08-01

    Interprofessional education and ethics education are two educational programs that blend together well, and, moreover, they are a natural fit for teaching in an academic health science center. The purpose of this paper is to describe our recent journey of developing and implementing an interprofessional ethics curriculum across the six schools of UTHealth. We provide an overview of the goals of the Campus-wide Ethics Program, which is housed in the McGovern Center for Humanities and Ethics, and we highlight certain innovative developments that are the result of the collaborative work of faculty and administrators from all six schools of UTHealth. In addition, a brief synopsis of the specific didactic and clinical courses in which ethics is a significant component is outlined for both the dental and the dental hygiene curricula. Lastly, we describe some of the recent scholarly activities that are a product of this new program. We are excited about our evolving efforts and the potential benefits of weaving interprofessional ethics within our school and across our campus. This article tells the story of our journey beyond "the silos" that are common among academic health science centers. PMID:21957783

  7. The Journey through Grief: Insights from a Qualitative Study of Electronic Health Record Implementation

    PubMed Central

    McAlearney, Ann Scheck; Hefner, Jennifer L; Sieck, Cynthia J; Huerta, Timothy R

    2015-01-01

    Objective To improve understanding of facilitators of EHR system implementation, paying particular attention to opportunities to maximize physician adoption and effective deployment. Data Sources/Study Setting Primary data collected from 47 physician and 35 administrative key informants from six U.S. health care organizations identified because of purported success with EHR implementation. Study Design We conducted interviews and focus groups in an extensive qualitative study. Data Collection/Extraction Methods Verbatim transcripts were analyzed both deductively and inductively using the constant comparative method. Principal Findings Conceptualizing EHR adoption as loss through the lens of Kübler-Ross's five stages of grief model may help individuals and organizations more effectively orient to the challenge of change. Coupled with Kotter's eight-step change management framework, we offer a structure to facilitate organizations' movement through the EHR implementation journey. Combining insights from these frameworks, we identify 10 EHR strategies that can help address EHR implementation barriers. Conclusions Loss is one part of change often overlooked. Addressing it directly and compassionately can potentially facilitate the EHR implementation journey. We offer a summarized list of deployment strategies that are sensitive to these issues to support physician transition to new technologies that will bring value to clinical practice. PMID:25219627

  8. Ambivalent journeys of hope: embryonic stem cell therapy in a clinic in India.

    PubMed

    Prasad, Amit

    2015-03-01

    Stem cell therapy in non-Western countries such as India has received a lot of attention. Apart from media reports, there are a number of social science analyses of stem cell policy, therapy, and research, their ethical implications, and impact of advertising on patients. Nevertheless, in the media reports as well as in academic studies, experiences of patients, who undertake overseas journeys for stem cell therapy, have largely been either ignored or presented reductively, often as a "false hope." In this article, I analyze the experiences of patients and their "journeys of hope" to NuTech Mediworld, an embryonic stem cell therapy clinic in New Delhi, India. My analysis, which draws on my observations in the clinic and patients' experiences, instead of seeking to adjudicate whether embryonic stem cell therapy in clinics such as NuTech is right or wrong, true or false, focuses on how patients navigate and contest these concerns. I utilize Gilles Deleuze and Felix Guattari's "concepts," lines of flight and deterritorialization, to highlight how embryonic stem cell therapy's "political economy of hope" embodies deterritorialization of several "regimes of truth" and how these deterritorializations impact patients' experiences. PMID:25394653

  9. Engaging in Action Research: A Personal and Professional Journey towards an Inquiry into Teacher Morale in a Senior Secondary College

    ERIC Educational Resources Information Center

    Moloney, Jennifer

    2009-01-01

    This article, written as a reflexive story, describes my journey as a practitioner researcher investigating the implementation of a study-group format in place of a formal meeting arrangement for the teaching team I lead. The inquiry has been initiated to explore the intervention as a way to promote teacher morale. The research site is a large…

  10. Mapping the Ethnographic Journey: A "Road Map" for Novice Researchers Wanting to Engage in Ethnography, Critical Theory and Policy Analysis

    ERIC Educational Resources Information Center

    Naidu, Sham

    2012-01-01

    In this article, the "researcher" narrates the issues faced by novice researchers in choosing the correct lenses to conduct research when searching for the truth via the use of qualitative methodology. It is argued that choosing an appropriate research approach and methodology can be described as an "arduous" journey. For the inexperienced…

  11. The Journey of a Sandwich: Computer-Based Laboratory Experiments about the Human Digestive System in High School Biology Teaching

    ERIC Educational Resources Information Center

    Sorgo, Andrej; Hajdinjak, Zdravka; Briski, Darko

    2008-01-01

    Teaching high school students about the digestive system can be a challenge for a teacher when s/he wants to overcome rote learning of facts without a deeper understanding of the physiological processes inside the alimentary tract. A series of model experiments illustrating the journey of a sandwich was introduced into teaching high school…

  12. From Kabul to the Academy: Narratives of Afghan Women's Journeys to and through U.S. Doctoral Programs

    ERIC Educational Resources Information Center

    Aryan, Bushra

    2010-01-01

    This study explored the experiences of seven Afghan women pursuing doctoral degrees in a variety of disciplines and programs across the United States. The guiding question for this study was: What factors influence Afghan women's journeys to and experiences in doctoral programs? In an attempt to understand Afghan women doctoral students, I…

  13. Ashe City Schools' Journey to Recognize, Nurture, and Respond to the Potential in All Children via U-STARS-PLUS

    ERIC Educational Resources Information Center

    Kern, Angela Haywood

    2009-01-01

    Culturally/linguistically diverse and economically disadvantaged students are under-represented in gifted education programs. White middle-class children tend to be afforded the opportunity of gifted education services. This study analyzed Ashe City Schools' journey to implement Project U-STARS-PLUS in order to identify and serve…

  14. A 17-Year Case Study of an Elementary School's Journey: From Traditional School to Learning Community to Democratic School Community

    ERIC Educational Resources Information Center

    Cate, Jean McGregor; Vaughn, Courtney Ann; O'Hair, Mary John

    2006-01-01

    This case study explores one elementary school's 17-year evolution from a traditional Title I elementary school into a learning community and, eventually, a high-achieving democratic school community. The investigation adds specificity and context to the existing theoretical framework outlining this change process. The school's journey is…

  15. Can Mentoring and Reflection Cause Change in Teaching Practice? A Professional Development Journey of a Canadian Teacher Educator

    ERIC Educational Resources Information Center

    Chitpin, Stephanie

    2011-01-01

    This article explores elements of the professional development of a pre-tenured teacher education professor. I am that professor and I trace my journey of growth, which was aided by peer mentoring. First, I present a brief discussion on literature associated with mentoring that I found pertinent, followed by how mentoring has emerged as I…

  16. People Make Dreams Come True, and Technology Expands the Possibilities: An Educational Journey across the United States.

    ERIC Educational Resources Information Center

    Blondin, Mark; Blondin, Betsy; Blondin, Donald; Blondin, Kelly; Blondin, Stacy

    The Blondin family undertook a 9-month educational journey across the United States that revolved around a unique learning experience incorporating current technology. The family's three children were enrolled in Northwest Academy in northern Michigan, a science- and technology-based public academy for grades 6 through 12 that supported their plan…

  17. Employee Commitment in the Community College: A Case Study Resulting from a Baldrige-Based Quality Journey

    ERIC Educational Resources Information Center

    Dial, Bill R.

    2013-01-01

    The topic of quality in higher education in the United States has received much research attention in the last several years. Specifically, how traditional higher education can benefit from commencing on a quality journey. Subsequently, many colleges and universities have adopted and employed total quality concepts into their day-to-day management…

  18. Time-space modeling of journey-time exposure to traffic-related air pollution using GIS.

    PubMed

    Gulliver, John; Briggs, David J

    2005-01-01

    Journey-time exposures represent an important, though as yet little-studied, component of human exposure to traffic-related air pollution, potentially with important health effects. Methods for assessing journey-time exposures, either as part of epidemiological studies or for policy assessment, are, however, poorly developed. This paper describes the development and testing of a GIS-based system for modeling human journey-time exposures to traffic-related air pollution: STEMS (Space-Time Exposure Modeling System). The model integrates data on source activity, pollutant dispersion, and travel behavior to derive individual- or group-level exposure measures to atmospheric pollution. The model, which is designed to simulate exposures of people as they move through a changing air pollution field, was developed, validated, and trialed in Northampton, UK. The system currently uses ArcInfo to couple four separate submodels: a source activity/emission model (SATURN), a proprietary atmospheric dispersion model (ADMS-Urban), an empirically derived background air pollution model, and a purposely designed time-activity-based exposure model (TOTEM). This paper describes the structure of the modeling system; presents results of field calibration, validation, and sensitivity analysis; and illustrates the use of the model to analyze journey-time exposures of schoolchildren. PMID:15476729

  19. The Water of Life: Creative Non-Fiction and Lived Experience on an Interdisciplinary Canoe Journey on Scotland's River Spey

    ERIC Educational Resources Information Center

    Higgins, Peter; Wattchow, Brian

    2013-01-01

    This paper focuses on an educational encounter between staff, students and the River Spey, Scotland in September 2009. The themes of water and embodied and culturally constructed ways of knowing the river were used to inform a creative non-fiction narrative that was drafted during and shortly after the journey, and was later refined. Textual…

  20. Defining American Heroes: Analyzing the Metamorphosis of the War Hero in Twentieth Century War Films Using Joseph Campbell's, "Hero's Journey."

    ERIC Educational Resources Information Center

    Frith, Luci A.

    In "The Hero's Journey" Joseph Campbell identifies the patterns that inform the myths of the "hero" throughout recorded history. By using Campbell's template, this paper examines how the American war hero is portrayed and has been portrayed in film. The paper states that Americans not only define their war heroes in films but also use these film…

  1. An Introduction to Education Research Methods: Exploring the Learning Journey of Pre-Service Teachers in a Transnational Programme

    ERIC Educational Resources Information Center

    White, Sonia; Hepple, Erika; Tangen, Donna; Comelli, Marlana; Alwi, Amyzar; Shaari, Zaira Abu Hassan

    2016-01-01

    Internationally there is interest in developing the research skills of pre-service teachers as a means of ongoing professional renewal with a distinct need for systematic and longitudinal investigation of student learning. The current study takes a unique perspective by exploring the research learning journey of pre-service teachers participating…

  2. 2 Cases of Bullosis Diabeticorum following Long-Distance Journeys by Road: A Report of 2 Cases

    PubMed Central

    Bello, Fatima; Samaila, O. Modupe; Lawal, Yakubu; Nkoro, U. Kufre

    2012-01-01

    Background. Bullosis diabeticorum is a distinct, spontaneous, noninflammatory, and blistering condition of acral skin that is unique to diabetics. It is rare. Exact aetiopathogenesis is not known, but many attributed peripheral neuropathy as a potent risk factor, others hypothesized the role of trauma, UV light, and nephropathy. Aim. To present cases of bullosis diabeticorum following long-distance journeys by road. Methods. History and physical examinations were done on 2 diabetics who presented with bilateral feet bullae following a long journey. Biopsy of a circumferential area of the bullae including adjoining apparently normal skin was done. Results. Features of peripheral neuropathy were noted. One developed digital gangrene without features of peripheral vascular disease. Culture of aspirate from a bullae yielded Staphylococcus aureus. Tissue biopsy showed hyperkeratotic focally acanthotic pigmented epidermis with subcorneal separation of the granular layer of the epidermis by aggregates of viable and nonviable polymorphs and lymphocytes. There is mild acantholysis of the epidermis, and a fibrocollagenous dermis which is moderately infiltrated by lymphocytes. Conclusion. Long journeys by road is a strong factor in the aetiopathogenesis of bullosis diabeticorum on a background of peripheral neuropathy. Diabetics especially those with peripheral neuropathy should be cautious while traveling long journeys by road. PMID:23119191

  3. GeoJourney: A Field-Based, Interdisciplinary Approach to Teaching Geology, Native American Cultures, and Environmental Studies

    ERIC Educational Resources Information Center

    Elkins, Joe; Elkins, Nichole M. L.; Hemmings, Sarah N. J.

    2008-01-01

    GeoJourney is an interdisciplinary field trip in geology, Native American studies, and environmental studies designed for introductory-level undergraduates. The program travels 23,345 kilometers by van to national parks, industrial sites, museums, and Indian reservations in 24 of the United States. During the day, students carry out hands-on…

  4. Female and male Hispanic students majoring in science or engineering: Their stories describing their educational journeys

    NASA Astrophysics Data System (ADS)

    Brown, Susan Wightman

    National statistics clearly demonstrate an underrepresentation of minorities in the fields of science and engineering. Blacks, Hispanics, American Indians, and Asians do not typically choose science or engineering as their college major; therefore, there is a very small representation of these minorities in the science and engineering labor force. The decision not to major in science and engineering may begin as soon as the child can begin to recognize role models in the media. News stories, magazine articles, television programs, teachers, parents, administrators, and other agencies have painted the picture of a scientist or engineer as being dominantly a White male. Schools have continued society's portrayal by using curriculum, textbooks, role models, instructional strategies, and counseling that continues to encourage the White male to succeed in science and engineering, but discourages the minority students, male and female, from succeeding in these fields. In this qualitative study, 22 Hispanic students, 12 female and 10 male, who are majoring in science or engineering, were interviewed using Seidman's in-depth interviewing technique. These students were shadowed in their college science or engineering classes; their high school and college transcripts were analyzed; and, a focus group was brought together at the end of the interviewing process in order to allow interaction between the participants. The goal was to explore the educational journeys of the 22 Hispanic students. What made a difference in the journeys of these 22 students so that they could succeed in majors that have historically discouraged minority students? Seven themes emerged: family support, honors program, challenging and interactive curriculum, college preparation in high school courses, caring and kind teachers, small class size, and small communities. Gender comparison of the educational journeys documents these differences between the females and males: college preparation, mentoring

  5. Environmental Journey

    ERIC Educational Resources Information Center

    Buccianeri, Rosemary; Shimkanin, John

    2005-01-01

    When Gary Hamilton became principal of Monongahela Elementary Center (MEC) over 10 years ago, he wanted to establish a nature trail on the four acres of wooded area on the east side of the school. "Children today are into so many structured activities they are denied opportunities to learn about nature firsthand," he said. "I want kids to…

  6. Generational Journeys

    ERIC Educational Resources Information Center

    Gordon, Rachel Singer

    2005-01-01

    When discussing NextGen concerns, common problems are faced in talking about any difference. These include the perception that pointing out differences is exclusionary; the misunderstanding that talking about the issues facing NextGen's means those issues are exclusive to that group; and the problem that people's interaction with individuals tends…

  7. Sharon's Journey.

    ERIC Educational Resources Information Center

    Miller, Geri

    2000-01-01

    This article describes an indigent, European American female client's spiritual issues concerning her relationship struggles and the lack of meaning in her life. The client's premonition of her death, a primary influence on her counseling, is discussed. (Author)

  8. A model of the biogeographical journey from Proto-pan to Pan paniscus.

    PubMed

    Myers Thompson, Jo A

    2003-04-01

    Pan paniscus is unique in the group of African apes because of its range south of the Congo River. Examination of the bio-geographical journey of the genus Pan to the species P. paniscus is important when discussing the evolution of African apes. This paper is a review of the paleo-geographic events, the zoogeography, and faunal sorting which influenced P. paniscus divergence from the Proto-pan ancestor within the recent Miocene through Pliocene Epochs, approximately 10-2 MYA. Finally, by elucidating modern day evidence of food plant forms in the southern periphery exploited by P. paniscus in the forest/savanna mosaic habitat, we are able to conclude with those extrinsic events that most influenced the occurrence and distribution of P. paniscus. PMID:12687485

  9. A Journey in Standard Development: The Core Manufacturing Simulation Data (CMSD) Information Model

    PubMed Central

    Lee, Yung-Tsun Tina

    2015-01-01

    This report documents a journey “from research to an approved standard” of a NIST-led standard development activity. That standard, Core Manufacturing Simulation Data (CMSD) information model, provides neutral structures for the efficient exchange of manufacturing data in a simulation environment. The model was standardized under the auspices of the international Simulation Interoperability Standards Organization (SISO). NIST started the research in 2001 and initiated the standardization effort in 2004. The CMSD standard was published in two SISO Products. In the first Product, the information model was defined in the Unified Modeling Language (UML) and published in 2010 as SISO-STD-008-2010. In the second Product, the information model was defined in Extensible Markup Language (XML) and published in 2013 as SISO-STD-008-01-2012. Both SISO-STD-008-2010 and SISO-STD-008-01-2012 are intended to be used together. PMID:26958450

  10. A Journey in Science: The Privilege of Exploring the Brain and the Immune System

    PubMed Central

    Steinman, Lawrence

    2016-01-01

    Real innovations in medicine and science are historic and singular; the stories behind each occurrence are precious. At Molecular Medicine we have established the Anthony Cerami Award in Translational Medicine to document and preserve these histories. The monographs recount the seminal events as told in the voice of the original investigators who provided the crucial early insight. These essays capture the essence of discovery, chronicling the birth of ideas that created new fields of research; and launched trajectories that persisted and ultimately influenced how disease is prevented, diagnosed, and treated. In this volume, the Cerami Award Monograph is by Lawrence Steinman, MD, of Stanford University in California. A visionary in the field of neurology, this is the story of Dr. Steinman’s scientific journey.

  11. Looking back, looking forward: Recovery journeys in a high secure hospital.

    PubMed

    McKeown, Mick; Jones, Fiona; Foy, Paul; Wright, Karen; Paxton, Tracey; Blackmon, Mike

    2016-06-01

    A qualitative study of staff and service users' views of recovery was undertaken in a UK high secure hospital working to implement recovery practices. 30 staff and 25 service users participated in semi-structured interviews or focus groups. Thematic analysis identified four broad accounts of how recovery was made sense of in the high secure environment: the importance of meaningful occupation; valuing relationships; recovery journeys and dialogue with the past; and recovery as personal responsibility. These themes are discussed with an emphasis on service user strategies of cooperation or resistance, respectively advancing or impeding progress through the system. In this context the notion of cooperation is, for many, commensurate with compliance with a dominant medical model. The policy framing of recovery opens up contemplation of treatment alternatives, more participatory approaches to risk management, and emphasise the value of relational skills, but may not elude the overarching bio-psychiatric episteme. PMID:26871912

  12. Role of the clinical nurse specialist in the journey to magnet recognition.

    PubMed

    Hanson, M Dave

    2015-01-01

    Clinical nurse specialists (CNSs) work with and through other nurses as well as interprofessional team members to advance nursing practice, improve outcomes, and provide clinical expertise to effect system-wide changes to improve programs of care. They practice across the continuum and through 3 spheres of influence, encompassing the patient, nurse, and system. Clinical nurse specialists possess expertise in developing and refining structures, strategies, and processes to optimize outcomes at both the unit (micro) level and the organization or system (macro) level. This unique vantage point positions CNSs as ideal individuals to assume several key roles when a health care organization makes the decision to embark on the Magnet journey and to maintain Magnet recognition. The competence and competencies of CNSs and a health care organization's desire to achieve and/or maintain Magnet recognition represent a synergistic match. PMID:25594480

  13. A Journey in Standard Development: The Core Manufacturing Simulation Data (CMSD) Information Model.

    PubMed

    Lee, Yung-Tsun Tina

    2015-01-01

    This report documents a journey "from research to an approved standard" of a NIST-led standard development activity. That standard, Core Manufacturing Simulation Data (CMSD) information model, provides neutral structures for the efficient exchange of manufacturing data in a simulation environment. The model was standardized under the auspices of the international Simulation Interoperability Standards Organization (SISO). NIST started the research in 2001 and initiated the standardization effort in 2004. The CMSD standard was published in two SISO Products. In the first Product, the information model was defined in the Unified Modeling Language (UML) and published in 2010 as SISO-STD-008-2010. In the second Product, the information model was defined in Extensible Markup Language (XML) and published in 2013 as SISO-STD-008-01-2012. Both SISO-STD-008-2010 and SISO-STD-008-01-2012 are intended to be used together. PMID:26958450

  14. Coping strategies used by survivors of childhood sexual abuse on the journey to recovery.

    PubMed

    Phanichrat, Thanomjit; Townshend, Julia M

    2010-01-01

    This interpretative phenomenological analysis study explored seven adult survivors' experiences of coping with childhood sexual abuse and identified their coping strategies on the road to recovery. Data for the analysis was collected using semistructured interviews. The analytical process yielded two key theme clusters: avoidant coping strategies and problem-focused coping strategies. The participants journeyed through similar gradual and dynamic coping processes by initially adopting avoidant strategies before turning to problem-focused ones. A healthy process of coping with sexual abuse involved seeking support, cognitive engagement, optimistic thinking, self-acceptance, and seeking meaning strategies. This study suggests that problem-focused coping strategies should be promoted as part of therapeutic intervention. PMID:20390779

  15. The start of the transplant journey: referral for pediatric solid organ transplantation.

    PubMed

    Shellmer, Diana; Brosig, Cheryl; Wray, Jo

    2014-03-01

    The focus of the majority of the psychosocial transplant literature is on post-transplant outcomes, but the transplant journey starts much earlier than this, at the point when transplantation is first considered and a referral for transplant evaluation is made. In this review, we cover information regarding the meaning of the referral process for solid organ transplantation. We discuss various factors of the referral for transplantation including the impact of referral on the pediatric patient and the family, potential expectations and misconceptions held by pediatric patients and parents, the role of health literacy, decision-making factors, and the informational needs of pediatric patients and parents. We elucidate steps that providers can take to enhance transplant referral and provide suggestions for much needed research within this area. PMID:24438194

  16. The Journey Project: a case study in providing health information to mitigate health disparities

    PubMed Central

    Leisey, Monica

    2009-01-01

    The Journey Project, part of the Virginia Commonwealth University Libraries' Social Work Information Specialist in Context Fellowship, was designed to merge social work and consumer health librarianship skills in order to improve the provision of health information to patients. A resource notebook was created encompassing the many dimensions of cancer health information. A social work informationist distributed the notebooks and provided individualized consultations with respect to patients' health information needs. Areas of congruence as well as key differences between social work and consumer health librarianship emerged during the course of the project. Merging the two professions into the role of a social work informationist increased the ability to attend holistically to clients' health information needs. PMID:19159008

  17. Before the long journey: Development of Soviet space biology and medicine

    NASA Technical Reports Server (NTRS)

    Gazenko, O. G.

    1978-01-01

    Academician O. Gazenko, Chief of the Institute of Biomedical Problems, USSR Ministry of Public Health, reviewed the short but intense history of Soviet research in space biology and medicine. The solid academic approach of the Soviet Academy of Sciences in giving a good start at the very beginning of the space age is stressed and key people and institutions who initiated these studies are named. The basic feature of the first period of space biology is seen as the search for answers to a few fundamental questions of survival in space. It is pointed out that the initiated investigations were replaced by refined, in-depth studies of the biological, biophysical, and biochemical processes in human organism in the space environment and the search for methods which should enable cosmonaut crews to live in space for several years during interplanetary journeys. Discussing the typical problems of this effort, Gazenko each time showed how they benefit medical science and practice in general.

  18. Shaping cancer nanomedicine: The effect of particle shape on the in vivo journey of nanoparticles

    PubMed Central

    Toy, Randall; Peiris, Pubudu M.; Ghaghada, Ketan B.; Karathanasis, Efstathios

    2014-01-01

    Summary Recent advances in nanoparticle technology have enabled the fabrication of nanoparticle classes with unique size, shape, and materials, which in turn has facilitated major advancements in the field of nanomedicine. More specifically, in the last decade, nanoscientists have recognized that nanomedicine exhibits a highly engineerable nature that makes it a mainstream scientific discipline, which is governed by its own distinctive principles in terms of interactions with cells and intravascular, transvascular and interstitial transport. This review focuses on recent developments and understanding of the relation between the shape of a nanoparticle and its navigation through different biological processes. Importantly, we seek to illustrate that the shape of a nanoparticle can govern its in vivo journey and destination dictating its biodistribution, intravascular and transvascular transport, and ultimately targeting of difficult-to-reach cancer sites. PMID:24354814

  19. First steps in the journey from consumers to producers of research in deaf education.

    PubMed

    Gardiner-Walsh, Stephanie; Kemmery, Megan; Compton, Mary V

    2014-01-01

    Faculty shortages in the study of low-incidence sensory disabilities (deafness, blindness, deaf-blindness) constitute personnel preparation challenges, as documented by a variety of organizations. To alleviate this deficit in the low-incidence sensory disability professoriat, the National Leadership Consortium for Sensory Disabilities (NLCSD) was created to support the preparation of preservice researchers in these disciplines. This qualitative study documents the emerging perceptions of research by deafness-focused NLCSD first-year doctoral Fellows during their participation in an online enrichment seminar. Thematic analysis of the online interactions of the Fellows reveals their initial steps in their journey from consumers to producers of research. Results of the study offer insight into the preparation process of leadership personnel in deaf education. PMID:25051883

  20. UNFINISHED JOURNEY Project. Final report, September 30, 1994--September 29, 1995

    SciTech Connect

    1998-02-01

    In late 1994, the U.S. Department of Energy (Nevada Operations Office) made a $199,708 grant (through the Mathematics, Science, and Technology Education Program), to the UNFINISHED JOURNEY Project. The Project began in April, 1994, to develop and implement an innovative model of student outreach by San Jose State University (SJSU) to underserved, underrepresented student populations of the East Side Union High School District (ESUHSD). The Project was formed by a consortium involving SJSU, ESUHSD, some 20 private sector organizations (foundations/corporations), numerous local community/professional organizations, and approximately 100 private funders. This proposal to the U.S. Department of Energy was to have the Department join this unique partnership to focus University outreach to underserved student populations to pursue careers in mathematics, science, and technology.

  1. The journey to accepting support: how parents of profoundly disabled children experience support in their lives.

    PubMed

    Brett, Jane

    2004-10-01

    Advances in medical knowledge and care have extended the lives of children with profound and multiple disabilities. In most cases it is the parents who meet the often complex and continual needs of their child with disabilities in their own home. This study explored the experience of support in the lives of such parents. The interpretive, hermeneutic phenomenology of Heidegger was employed to create a detailed and authentic account of the parents' experiences of support. Five interrelated themes emerged from data from in-depth interviews with six parents randomly selected from a purposive sample in a special school setting. The themes were: parents' feelings about support, the journey to accepting support, support as a loss, disability and the parent and the supportive relationship. Understanding the experience of support from the parent's perspective may lead to a consideration of flexible systems that challenge practice to ensure that supporters listen, learn, develop and deliver support in ways that are helpful. PMID:15537108

  2. A Journey Through a Leaf: Phenomics Analysis of Leaf Growth in Arabidopsis thaliana

    PubMed Central

    Vanhaeren, Hannes; Gonzalez, Nathalie; Inzé, Dirk

    2015-01-01

    In Arabidopsis, leaves contribute to the largest part of the aboveground biomass. In these organs, light is captured and converted into chemical energy, which plants use to grow and complete their life cycle. Leaves emerge as a small pool of cells at the vegetative shoot apical meristem and develop into planar, complex organs through different interconnected cellular events. Over the last decade, numerous phenotyping techniques have been developed to visualize and quantify leaf size and growth, leading to the identification of numerous genes that contribute to the final size of leaves. In this review, we will start at the Arabidopsis rosette level and gradually zoom in from a macroscopic view on leaf growth to a microscopic and molecular view. Along this journey, we describe different techniques that have been key to identify important events during leaf development and discuss approaches that will further help unraveling the complex cellular and molecular mechanisms that underlie leaf growth. PMID:26217168

  3. Parents' perspective of their journey caring for a child with chronic neuropathic pain.

    PubMed

    Gaughan, Veronica; Logan, Deirdre; Sethna, Navil; Mott, Sandra

    2014-03-01

    When a child has chronic pain, it affects the parents. Their response and how it is factored into their lives and family function was the phenomenon of interest that drove this study. The available literature was sparse, especially when the pain etiology was neuropathic. The purpose of this study was to describe the parents' perception of the pain journey from the initial occurrence of their child's pain through the labyrinth of treatment options to successful outcome, to gain a better understanding of parental beliefs about pain, and to learn how parental attitudes and behaviors relate to children's response to treatment for chronic pain. Qualitative descriptive design was used to better understand the phenomenon from those who were the experts because they had experienced it. Parents whose child was enrolled in a pain rehabilitation program participated in open-ended interviews. The children/adolescents were 8-18 years old and diagnosed with complex regional pain syndrome or a related chronic pain condition. During data immersion, the investigators uncovered the pervasive underlying themes of suffering and disempowerment. In addition, the multiple meaning elements were grouped into three categories and supportive subcategories labeled as follows: parent distress, with subcategories schism in parenting, searching, and disabled parenting; and lack of control, with the subcategories family/community, fear, and empowerment. The voices of parents were heard in their description of the exhausting and difficult journey in search of pain relief for their child. Their comments provided insight into how they defined the child's pain and their related parental role. PMID:23219393

  4. Health inequalities in Scotland and England: the contrasting journeys of ideas from research into policy.

    PubMed

    Smith, Katherine Elizabeth

    2007-04-01

    Both the UK's Labour Government and Scotland's devolved Labour-Liberal Democrat coalition Executive have committed themselves to reducing health inequalities. Furthermore, both institutions have emphasised the importance of using evidence to inform policy responses. In light of such political commitments, a significant amount of work has been undertaken in the field of health inequalities in order to: (i) review the available research evidence; (ii) assess the extent to which policies have been based on this research evidence; and (iii) evaluate the success (or failure) of policies to tackle health inequalities. Yet so far only limited attention has been given to exploring how key actors involved in research-policy dialogues understand the processes involved. In an attempt to address this gap, this article draws on data from semi-structured interviews with 58 key actors in the field of health inequalities research and policymaking in the UK to argue that it is ideas, rather than research evidence, which have travelled from research into policy. The descriptions of the varying journeys of these ideas fit three types--successful, partial and fractured--each of which is outlined with reference to one example. The paper then employs existing theories about research-policy relations and the movement of ideas in an attempt to illuminate and better understand the contrasting journeys. In the concluding discussion, it is argued that the third approach, which focuses on the entrepreneurial processes involved in the marketing of ideas, is most helpful in understanding the research findings, but that this needs to be discussed in relation to the political context within which negotiations take place. PMID:17222955

  5. Solar Journey: The Significance of Our Galactic Environment for the Heliosphere and Earth

    NASA Astrophysics Data System (ADS)

    Frisch, Priscilla C.

    2006-09-01

    Humans evolved when the Sun was in the great void of the Local Bubble . The Sun entered the present environment of interstellar clouds only during the late Quaternary. Astronomical data reveal these long and short term changes in our galactic environment. Theoretical models then tell us how these changes affect interplanetary particles, planetary magnetospheres, and the Earth itself. Cosmic rays leave an isotopic signature in the paleoclimate record that helps trace the solar journey through space. "Solar Journey: The Significance of Our Galactic Environment for the Heliosphere and Earth" lays the foundation for an interdisciplinary study of the influence of interstellar material on the solar system and Earth as we travel through the Milky Way Galaxy. The solar wind bubble responds dynamically to interstellar material flowing past the Sun, regulating interstellar gas, dust, and cosmic particle fluxes in the interplanetary medium and the Earth. Cones of interstellar gas and dust focused by solar gravity, the magnetospheres of the outer planets, and cosmic rays at Earth all might yield the first hints of changes in our galactic environment. Twelve articles from leading experts in diverse fields discuss the physical changes expected as the heliosphere adjusts to its galactic environment. Topics include the interaction between the solar wind and interstellar dust and gas, cosmic ray modulation, magnetospheres, temporal variations in the solar environment, and the cosmic ray isotope record preserved in paleoclimate data. The breadth of processes discussed in this book make it a valuable resource for scientists and students doing research in the fields of Space Physics, Astronomy and the Paleoclimate. Link: http://www.springer.com/east/home?SGWID=5-102-22-144940498-0&changeHeader=true

  6. Solar Journey: The Significance of our Galactic Environment for the Heliosphere and Earth

    NASA Astrophysics Data System (ADS)

    Frisch, Priscilla C.

    2006-09-01

    Humans evolved when the Sun was in the great void of the Local Bubble . The Sun entered the present environment of interstellar clouds only during the late Quaternary. Astronomical data reveal these long and short term changes in our galactic environment. Theoretical models then tell us how these changes affect interplanetary particles, planetary magnetospheres, and the Earth itself. Cosmic rays leave an isotopic signature in the paleoclimate record that helps trace the solar journey through space. "Solar Journey: The Significance of Our Galactic Environment for the Heliosphere and Earth" lays the foundation for an interdisciplinary study of the influence of interstellar material on the solar system and Earth as we travel through the Milky Way Galaxy. The solar wind bubble responds dynamically to interstellar material flowing past the Sun, regulating interstellar gas, dust, and cosmic particle fluxes in the interplanetary medium and the Earth. Cones of interstellar gas and dust focused by solar gravity, the magnetospheres of the outer planets, and cosmic rays at Earth all might yield the first hints of changes in our galactic environment. Twelve articles from leading experts in diverse fields discuss the physical changes expected as the heliosphere adjusts to its galactic environment. Topics include the interaction between the solar wind and interstellar dust and gas, cosmic ray modulation, magnetospheres, temporal variations in the solar environment, and the cosmic ray isotoperecord preserved in paleoclimate data. The breadth of processes discussed in this book make it a valuable resource for scientists and students doing research in the fields of Space Physics, Astronomy and the Paleoclimate. Link: http://www.springer.com/east/home?SGWID=5-102-22-144940498-0&changeHeader=true

  7. SMART-1 leaves Earth on a long journey to the Moon

    NASA Astrophysics Data System (ADS)

    2003-09-01

    The European Space Agency’s SMART-1 was one of three payloads on Ariane Flight 162. The generic Ariane-5 lifted off from the Guiana Space Centre, Europe’s spaceport at Kourou, French Guiana, at 2014 hrs local time (2314 hrs GMT) on 27 September (01:14 Central European Summer time on 28 September). 42 minutes after launch, SMART-1 as last of the three satellites had been successfully released into a geostationary transfer orbit (654 x 35 885 km, inclined at 7 degrees to the Equator). While the other two satellites are due to manoeuvre towards geostationary orbit, the 367 kg SMART-1 will begin a much longer journey to a target ten times more distant than the geostationary orbit: the Moon. “Europe can be proud”, said ESA Director General Jean-Jacques Dordain, after witnessing the launch from ESA’s ESOC space operations centre in Darmstadt, Germany, “we have set course for the Moon again. And this is only the beginning: we are preparing to reach much further”. The spacecraft has deployed its solar arrays and is currently undergoing initial checkout of its systems under control from ESA/ESOC. This checkout will continue until 4 October and will include with the initial firing of SMART-1’s innovative ion engine. By ion drive to the Moon “Science and technology go hand in hand in this exciting mission to the Moon. The Earth and Moon have over 4 thousand million years of shared history, so knowing the Moon better will help scientists in Europe and all over the world to better understand our planet and will give them valuable new hints on how to better safeguard it” said ESA Director of Science David Southwood, following the launch from Kourou. As the first mission in the new series of Small Missions for Advanced Research in Technology, SMART-1 is mainly designed to demonstrate innovative and key technologies for future deep space science missions. The first technology to be demonstrated on SMART-1 will be Solar Electric Primary Propulsion (SEPP), a

  8. Lipid-based siRNA Delivery Systems: Challenges, Promises and Solutions Along the Long Journey.

    PubMed

    Sarisozen, Can; Salzano, Giuseppina; Torchilin, Vladimir P

    2016-01-01

    RNA interference (RNAi) is an evolutionary conserved highly specific gene-silencing mechanism initiated by small interfering RNA (siRNA) molecules. Fast-paced preclinical and clinical studies helped the siRNA technology become an efficient tool for undruggable targets in different diseases including genetic diseases, viral diseases and cancer. Despite great feature of siRNAs that can down-regulate any protein in the cells, the full potential and the success of the preclinical studies could not be translated into largely successful clinical outcomes. It has become clear that the possibility of overcoming the pitfalls for in vivo siRNA therapy fully depends on delivery systems. In this review, we start with the challenges and barriers for in vivo siRNA delivery. Then we briefly discuss the recent developments in siRNA modification technology. We specifically focused on siRNA lipidation and delivery approaches with special emphasis on the lipid based hybrid systems. Here we summarize the journey of lipid-based micelle-like nanoparticle systems that combine longevity in blood, effective cellular uptake and endosomal escape for successful siRNA delivery and discuss the multifunctional stimuli-sensitive systems based on lipids as the next generation smart systems. PMID:27033509

  9. The hospital of the future: the vision, the journey, the reality.

    PubMed

    Covert, Michael H

    2014-01-01

    Palomar Medical Center, like many California healthcare institutions in the 1990s, faced the challenge of needing to meet state building seismic requirements. As a result of the mandate and infrastructure demands that would need to be made to accommodate the new standards, the health system set out to assess the larger needs of the communities served, evaluate the medical and technological changes that would be part of future clinical care delivery systems, and assess our capability to meet the financial impact such changes would have on the organization. This article shares our journey to build a new hospital--one that could be studied by other health systems facing the same or similar challenges. It incorporates elements associated with the concept of "Fable Hospital"--a design promulgated by leading architects and designers from around the world and researched by the Center for Health Design--which considers the use of evidenced-based principles gathered over the past 20 years that, when incorporated, can lead to the creation of buildings that enhance the quality of care, provide safety for patients and staff, and meet the needs of patients and families in meaningful ways. Finally, Palomar Medical Center is an environment that allows for effective, flexible integration of technology and expansion of staff while improving the efficiency of operations that are critical to the management of the hospital in a changing healthcare delivery world. PMID:25671998

  10. Coast Salish and U.S. Geological Survey 2009 Tribal Journey water quality project

    USGS Publications Warehouse

    Akin, Sarah K.; Grossman, Eric E.

    2010-01-01

    The Salish Sea, contained within the United States and British Columbia, Canada, is the homeland of the Coast Salish Peoples and contains a diverse array of marine resources unique to this area that have sustained Coast Salish cultures and traditions for millennia. In July 2009, the Coast Salish People and U.S. Geological Survey conducted a second water quality study of the Salish Sea to examine spatial and temporal variability of environmental conditions of these surface waters as part of the annual Tribal Journey. Six canoes of approximately 100 towed multi parameter water-quality sondes as the Salish People traveled their ancestral waters during the middle of summer. Sea surface temperature, salinity, pH, dissolved oxygen, and turbidity were measured simultaneously at ten-second intervals, and more than 54,000 data points spanning 1,300 kilometers of the Salish Sea were collected. The project also synthesized Coast Salish ecological knowledge and culture with scientific monitoring to better understand and predict the response of coastal habitats and marine resources. Comparisons with data collected in 2008 reveal significantly higher mean surface-water temperatures in most subbasins in 2009 linked to record air temperatures that affected the Pacific Northwest in July 2009. Through large-scale spatial measurements collected each summer, the project helps to identify patterns in summer water quality, areas of water-quality impairment, and trends occurring through time.

  11. Writing for self-discovery: a semester-long journey at the graduate level.

    PubMed

    Hays, Mary M

    2005-01-01

    Writing for self-discovery begins on the first day of class and continues throughout the semester. Class introduction compares this journey to flying an airplane, requiring adjustments to successfully reach the destination. A systems framework promotes writing-to-learn and writing as a self-discovery tool for graduate nursing administration students in this clinical preceptorship. Because writing-to-learn is an unfamiliar concept for many students, the process is incorporated into the self-evaluation tools of writing discovery and intention statements, keeping a clinical learning log, reflective questioning, and feedback strategies. The purpose is to foster the critical administrative processes of writing, thinking, analyzing, and synthesizing. Written instructor feedback probes the relationships between concepts and their relationships with students' learning. Future strategies will include additional formative and summative self-evaluative tools, including videotaping, to foster awareness of self in a written format for both students and instructor. The goal is to prepare master's graduates who are creative thinkers, self-evaluators, and analytical writers for service in clinical and administrative settings. PMID:15682161

  12. Co-rich Mn crusts from the Magellan Seamount cluster: the long journey through time

    NASA Astrophysics Data System (ADS)

    Glasby, Geoffrey P.; Ren, Xiangwen; Shi, Xuefa; Pulyaeva, Irina A.

    2007-10-01

    The Magellan seamounts began forming as large submarine shield volcanoes south of the equator during the Cretaceous. These volcanoes formed as a cluster on the small Pacific plate in a period when tectonic stress was absent. Thermal subsidence of the seafloor led to sinking of these volcanoes and the formation of guyots as the seamounts crossed the equatorial South Pacific (10-0°S) sequentially and ocean surface temperatures became too high for calcareous organisms to survive. Guyot formation was completed between about 59 and 45 Ma and the guyots became phosphatized at about 39-34 and 27-21 Ma. Ferromanganese crusts began formation as proto-crusts on the seamounts and guyots of the Magellan Seamount cluster towards the end of the Cretaceous up to 55 Ma after the formation of the seamounts themselves. The chemical composition of these crusts evolved over time in a series of steps in response to changes in global climate and ocean circulation. The great thickness of these crusts (up to 15-20 cm) reflects their very long period of growth. The high Co contents of the outer parts of the crusts are a consequence of the increasing deep circulation of the ocean and the resulting deepening of the oxygen minimum zone with time. Growth of the Co-rich Mn crusts in the Magellan Seamount cluster can be considered to be the culmination of a long journey through time.

  13. Many rivers to cross: the journey of zinc from soil to seed.

    PubMed

    Olsen, Lene I; Palmgren, Michael G

    2014-01-01

    An important goal of micronutrient biofortification is to enhance the amount of bioavailable zinc in the edible seed of cereals and more specifically in the endosperm. The picture is starting to emerge for how zinc is translocated from the soil through the mother plant to the developing seed. On this journey, zinc is transported from symplast to symplast via multiple apoplastic spaces. During each step, zinc is imported into a symplast before it is exported again. Cellular import and export of zinc requires passage through biological membranes, which makes membrane-bound transporters of zinc especially interesting as potential transport bottlenecks. Inside the cell, zinc can be imported into or exported out of organelles by other transporters. The function of several membrane proteins involved in the transport of zinc across the tonoplast, chloroplast or plasma membranes are currently known. These include members of the ZIP (ZRT-IRT-like Protein), and MTP (Metal Tolerance Protein) and heavy metal ATPase (HMA) families. An important player in the transport process is the ligand nicotianamine that binds zinc to increase its solubility in living cells and in this way buffers the intracellular zinc concentration. PMID:24575104

  14. Lipids implicated in the journey of a secretory granule: from biogenesis to fusion.

    PubMed

    Tanguy, Emeline; Carmon, Ophélie; Wang, Qili; Jeandel, Lydie; Chasserot-Golaz, Sylvette; Montero-Hadjadje, Maité; Vitale, Nicolas

    2016-06-01

    The regulated secretory pathway begins with the formation of secretory granules by budding from the Golgi apparatus and ends by their fusion with the plasma membrane leading to the release of their content into the extracellular space, generally following a rise in cytosolic calcium. Generation of these membrane-bound transport carriers can be classified into three steps: (i) cargo sorting that segregates the cargo from resident proteins of the Golgi apparatus, (ii) membrane budding that encloses the cargo and depends on the creation of appropriate membrane curvature, and (iii) membrane fission events allowing the nascent carrier to separate from the donor membrane. These secretory vesicles then mature as they are actively transported along microtubules toward the cortical actin network at the cell periphery. The final stage known as regulated exocytosis involves the docking and the priming of the mature granules, necessary for merging of vesicular and plasma membranes, and the subsequent partial or total release of the secretory vesicle content. Here, we review the latest evidence detailing the functional roles played by lipids during secretory granule biogenesis, recruitment, and exocytosis steps. In this review, we highlight evidence supporting the notion that lipids play important functions in secretory vesicle biogenesis, maturation, recruitment, and membrane fusion steps. These effects include regulating various protein distribution and activity, but also directly modulating membrane topology. The challenges ahead to understand the pleiotropic functions of lipids in a secretory granule's journey are also discussed. This article is part of a mini review series on Chromaffin cells (ISCCB Meeting, 2015). PMID:26877188

  15. [A journey into the (un)known. Borderlands of knowledge for Leonhard Rauwolf (1535?-1596)].

    PubMed

    Walter, Tilmann

    2009-01-01

    The Augsburg physician Leonhard Rauwolf is known to the history of Western sciences for "discovering" the exotic flora of the Near East. This article deals with the social background of his studies in Germany and France and his perception of foreign lands, plants, and peoples. Before Rauwolf started his journey at Marseille in 1573 he had received a proper education in practical botany at Montpellier under Guillaume Rondelet. He had also collected about 600 specimens of plants in his herbarium. According to the common medical conventions of his time--most prominently represented by the Renaissance anatomist Andreas Vesalius--in his travel account Rauwolf claimed to tell only what he had seen, experienced, observed by himself, or touched with his own hands. Contrary to his own claim of pure "autopsy", or direct experience, however, Rauwolf's Aigentliche Beschreibung [Actual Description] was composed from different sources. As previously unnoted manuscript letters from the Trew-collection at the University Library of Erlangen show, editorial work on Rauwolf's book was a lengthy process. The final composition ended up drawing on such different sources as the Old and New Testament, ancient natural philosophy, Christian travel literature and sermons, more recent botanical books, oral information from other academics, fellow travellers or indigenous people, and--finally--Rauwolf's own mpressions and observations. PMID:20481153

  16. Many rivers to cross: the journey of zinc from soil to seed

    PubMed Central

    Olsen, Lene I.; Palmgren, Michael G.

    2014-01-01

    An important goal of micronutrient biofortification is to enhance the amount of bioavailable zinc in the edible seed of cereals and more specifically in the endosperm. The picture is starting to emerge for how zinc is translocated from the soil through the mother plant to the developing seed. On this journey, zinc is transported from symplast to symplast via multiple apoplastic spaces. During each step, zinc is imported into a symplast before it is exported again. Cellular import and export of zinc requires passage through biological membranes, which makes membrane-bound transporters of zinc especially interesting as potential transport bottlenecks. Inside the cell, zinc can be imported into or exported out of organelles by other transporters. The function of several membrane proteins involved in the transport of zinc across the tonoplast, chloroplast or plasma membranes are currently known. These include members of the ZIP (ZRT-IRT-like Protein), and MTP (Metal Tolerance Protein) and heavy metal ATPase (HMA) families. An important player in the transport process is the ligand nicotianamine that binds zinc to increase its solubility in living cells and in this way buffers the intracellular zinc concentration. PMID:24575104

  17. Distilling the essence of general practice: a learning journey in progress

    PubMed Central

    Gillies, John CM; Mercer, Stewart W; Lyon, Andrew; Scott, Mairi; Watt, Graham CM

    2009-01-01

    Over the past 5 years, general practice in the UK has undergone major change. Starting with the introduction of the new GMS contract in 2004, it has continued apace with the establishment of Postgraduate Medical Education Training Board, a GP training curriculum, and nMRCGP. The NHS is developing very differently in the four countries of the UK. Regulation of the profession is under review, and a system of relicensing, recertification, and revalidation is being introduced. The Essence project, initiated by RCGP Scotland in conjunction with International Futures Forum 4 years ago is a constructive response to these changes. It has included learning journeys, a discussion day for GPs, and commissioned short pieces of 100 words from GPs and patients. From an analysis of these, some characteristics of the essence of general practice have been defined. These include key roles and core personal qualities for GPs. It is argued that general practice has important and unique advantages — trust, coordination, continuity, flexibility, universal coverage, and leadership — which mean that it should continue to be central to the development of primary care throughout the UK. PMID:19401010

  18. Intersections between immigration, language, identity, and emotions: a science teacher candidate's journey

    NASA Astrophysics Data System (ADS)

    Rivera Maulucci, Maria S.

    2008-04-01

    This study reports a subset of findings from a larger, ongoing study aimed at exploring interactions between teacher identity, learning, and classroom practices in a social justice teacher education program at a selective liberal arts college in New York. This case-study explores the journey of Elena, as an immigrant, a student, and a pre-service teacher candidate towards becoming a social justice educator. Elena reflects upon her school language experiences as an immigrant youth, her learning in a social justice teacher education program, and her field experiences in an international high school. The analysis spans macro-, meso-, and microlevels to explore the ways globalization, particularly immigration, as well as schooling policies for English language learners interact with aspects of Elena's core identity, particularly in school settings. The findings show some of the ways language and literacy verified and/or denied aspects of Elena's core identity; specific instances where second language proficiency was cast as power and privilege versus disadvantage according to ethnic, language, and class categorizations; and the struggles Elena, and other immigrant youth may face given the focus on English language acquisition and high stakes accountability in schools, at the expense of students' primary language proficiency and affirmation of core identity markers.

  19. Jules Verne's Journey to the centre of the Earth: the secret of counterdepressive narratives.

    PubMed

    Sanchez-Cardenas, Michel

    2005-12-01

    The author interprets Jules Verne's Journey to the centre of the Earth with the help of Matte Blanco's theoretical framework, which describes the principle of symmetry and the principle of generalization. The first states that, from the moment an element or a proposition becomes conscious, it coexists in the unconscious with its symmetrically opposite form. The second refers to the confusion of elements once they have been apprehended by thought as containing a common point; they are put into larger and larger groups which merge into an indivisible whole. Verne's novel is built on paired elements which become symmetrized (e.g. distinct minerals vs molten lava; scientific rationality vs madness; the living vs the dead, etc.). These elements in turn become confused with one another, thanks largely to the novel's atmosphere of oral incorporation. This allows the fusion between subject and object, and, in particular, between the orphaned hero and his dead (Earth) mother. The novel's narrative evolution through three stages (separation, fusion and de-fusion, which are paralleled by rational, irrational and rational thought) can thus be understood as a mourning process. Similar processes can be found in other literary works. PMID:16318945

  20. Breakthroughs in the biogeochemistry of Nordic aquatic systems: Lessons from Water's Journey from Rain to Stream

    NASA Astrophysics Data System (ADS)

    Bishop, Kevin

    2015-04-01

    A sustainable society has been said to require knowledge of the limits placed by nature. Whatever one's views on the know-ability and significance of such limits, science strives to improve our understanding of these limiting factors, of which water is recognized to be one of the most important. Despite the centrality of water, the water cycle is maddeningly difficulty to pin down with the level of detail that is desired for resolving issues about the fate of pollutants, nutrient cycling and the global carbon balance, etc. But there is hope lurking in the Swedish landscape. The simplicity of hydrology in many Fennoscandian till soils, combined with applications of the only true tracers of water (isotopes of the water molecule) that were pioneered by Uppsala University hydrologists -provide a hydrological basis for breakthroughs in the biogeochemistry of critical earth support systems. This talk will explore some recent advances in understanding both pollutants and natural cycles, with linkages back to the concepts presented in the Water's Journey from Rain to Stream by Harald Grip and Allan Rodhe. The examples will include the mercury, acidity, and biogenic carbon of relevance to the "aquatic conduit" in the global carbon cycle. The talk will finish with thoughts about where to go next with the power that a well-characterized hydrology can provide.

  1. Mapping the global journey of anthropogenic aluminum: a trade-linked multilevel material flow analysis.

    PubMed

    Liu, Gang; Müller, Daniel B

    2013-10-15

    Material cycles have become increasingly coupled and interconnected in a globalizing era. While material flow analysis (MFA) has been widely used to characterize stocks and flows along technological life cycle within a specific geographical area, trade networks among individual cycles have remained largely unexplored. Here we developed a trade-linked multilevel MFA model to map the contemporary global journey of anthropogenic aluminum. We demonstrate that the anthropogenic aluminum cycle depends substantially on international trade of aluminum in all forms and becomes highly interconnected in nature. While the Southern hemisphere is the main primary resource supplier, aluminum production and consumption concentrate in the Northern hemisphere, where we also find the largest potential for recycling. The more developed countries tend to have a substantial and increasing presence throughout the stages after bauxite refining and possess highly consumption-based cycles, thus maintaining advantages both economically and environmentally. A small group of countries plays a key role in the global redistribution of aluminum and in the connectivity of the network, which may render some countries vulnerable to supply disruption. The model provides potential insights to inform government and industry policies in resource criticality, supply chain security, value chain management, and cross-boundary environmental impacts mitigation. PMID:24025046

  2. The journey of positioning self as both mental health nurse and qualitative researcher: a critical reflection.

    PubMed

    Brunero, S J; Jeon, Y H; Foster, K

    2015-09-01

    This paper discusses the development of a mental health nurse clinician to a mental health nurse researcher. Understanding the theoretical and professional drives that shape mental health nurses clinical practice and how that links to becoming a researcher is discussed. Mental health nurses who conduct research have to often move between their clinical roles and that of the researcher, doing this safely using a reflective supervision approach enables the nurse to conduct the research from a stronger professional and ethical standpoint. The intention of the paper is to encourage mental health nurses to engage in research and development. Shifting between the positions of a mental health nurse clinician and a qualitative researcher has some parallels to the processes in the nurse-service user relationship. This paper addresses this development from practitioner to researcher in one mental health nurse's journey through a PhD study using constructivist grounded theory. The paper examines theoretical and professional drives that have shaped my clinical practice and the role of the researcher in constructivist grounded theory, the notion of the researcher shifting between insider and outsider status, and the importance of reflexivity in conducting research. These influences will be discussed in the context of the development of a constructivist grounded theory study of the delivery of health care to service users with a mental illness in general hospital wards. PMID:26234189

  3. Ciencia en Nepantla: the journey of Nepantler@s in science learning and teaching

    NASA Astrophysics Data System (ADS)

    Aguilar-Valdez, Jean R.; LópezLeiva, Carlos A.; Roberts-Harris, Deborah; Torres-Velásquez, Diane; Lobo, Gilberto; Westby, Carol

    2013-12-01

    This paper presents a new approach to science education that takes a path through sociocultural theory and into the ideas of Gloria Anzaldúa. We apply Anzaldúan theory to science education by illustrating it in action through various examples which explore the multidimensionality of teaching science with Latin@ students in various contexts including dual language settings. We present what it is to journey through transformation using examples from educators at various levels of science within the world of teaching science with Latin@ students in the U.S. Our examples illustrate how Latin@ students cross many cultural borders in Spanish, English, Latin@ home culture, school culture, and the world of scientific dialogue and content, and in doing so, go through tensions and transformations between dominant and non-dominant worlds, which should be acknowledged and better understood through Anzaldúan theory. Fundamentally, we present a transformative notion of Latin@ science learning as "living on the bridges" of many dialogic and cultural practices, and having to negotiate these in-between spaces, or " nepantla" (Anzaldúa and Keating in Interviews, Psychology Press, London, 2000), where Latin@ students must contend with the fragmented and sometimes painful struggle of living in racialized reality amidst the demands of a dominant culture, and where transformation and healing are possible through the path of conocimiento. We advocate for teachers to become science teacher nepantler@s, who guide their students through nepantla, and into a new mestiz@ consciousness of science education.

  4. The software engineering journey: From a naieve past into a responsible future

    SciTech Connect

    Chapa, S.K.

    1997-08-01

    All engineering fields experience growth, from early trial & error approaches, to disciplined approaches based on fundamental understanding. The field of software engineering is making the long and arduous journey, accomplished by evolution of thinking in many dimensions. This paper takes the reader along a trio of simultaneous evolutionary paths. First, the reader experiences evolution from a zero-risk mindset to a managed-risk mindset. Along this path, the reader observes three generations of security risk management and their implications for software system assurance. Next is a growth path from separate surety disciplines to an integrated systems surety approach. On the way, the reader visits safety, security, and dependability disciplines and peers into a future vision which coalesces them. The third and final evolutionary path explored here transitions the software engineering field from best practices to fundamental understanding. Along this road, the reader observes a framework for developing a {open_quotes}science behind the engineering{close_quotes}, and methodologies for software surety analysis.

  5. What If Education Is Not a Race?: The Need within Democratic Life to See Education as a Personal, Interpersonal, and Transpersonal Journey and the Present Possibilities for Helping the People to See This

    ERIC Educational Resources Information Center

    Novak, Bruce

    2010-01-01

    In this paper, the author outlines what No Child Left Behind policy might mean first in personal then in philosophical terms. First, the author will trace a bit of Obama's own educational development: how he was first set on a personal educational journey and how, proceeding along with that journey, he eventually came to successfully elicit "us"…

  6. Slow Boat to Centauri: A Millennial Journey Exploiting Resources Along the Way

    NASA Astrophysics Data System (ADS)

    Gilster, P. A.

    Before our species can begin interstellar exploration, a Solar System-wide infrastructure will need to be in place. Driving its construction will be two realities: 1) We will need to develop the technologies to alter the trajectories of Earth-crossing objects as a means of planetary security; 2) Our drive to understand our place in the universe will impel us to explore ever more distant targets to learn whether or not life exists elsewhere. Interstellar expansion is not likely to be sudden and disruptive but an evolutionary progression through a series of ever more distant targets that satisfy these imperatives. Exploration of the outer planets will search for life in sub-surface oceans on venues as distinct as Europa, Triton and numerous Kuiper Belt objects. Understanding the factors that disrupt the Oort Cloud will lead us to the study of what Freeman Dyson calls "iceteroids" and the possibility of exotic life even there. Rogue planets moving through interstellar space without stars are under investigation, with several candidate objects already identified. Before we reach even the nearest stars, we will examine these and consider the possibility of faint brown dwarfs in nearby space. Ultimately, our journey into the Orion Arm will witness many stops along the way. The Oort Cloud may extend halfway to Alpha Centauri and our dispersal can be gradual as we move between our own system and the possibly overlapping cometary cloud around the Alpha Centauri stars. Such "slow boat" migration may take tens of millennia but involves no technologies inconsistent with known physics.

  7. The journey from vitamin D-resistant rickets to the regulation of renal phosphate transport.

    PubMed

    Levine, Barton S; Kleeman, Charles R; Felsenfeld, Arnold J

    2009-11-01

    In 1937, Fuller Albright first described two rare genetic disorders: Vitamin D resistant rickets and polyostotic fibrous dysplasia, now respectively known as X-linked hypophosphatemic rickets (XLH) and the McCune-Albright syndrome. Albright carefully characterized and meticulously analyzed one patient, W.M., with vitamin D-resistant rickets. Albright subsequently reported additional carefully performed balance studies on W.M. In this review, which evaluates the journey from the initial description of vitamin D-resistant rickets (XLH) to the regulation of renal phosphate transport, we (1) trace the timeline of important discoveries in unraveling the pathophysiology of XLH, (2) cite the recognized abnormalities in mineral metabolism in XLH, (3) evaluate factors that may affect parathyroid hormone values in XLH, (4) assess the potential interactions between the phosphate-regulating gene with homology to endopeptidase on the X chromosome and fibroblast growth factor 23 (FGF23) and their resultant effects on renal phosphate transport and vitamin D metabolism, (5) analyze the complex interplay between FGF23 and the factors that regulate FGF23, and (6) discuss the genetic and acquired disorders of hypophosphatemia and hyperphosphatemia in which FGF23 plays a role. Although Albright could not measure parathyroid hormone, he concluded on the basis of his studies that showed calcemic resistance to parathyroid extract in W.M. that hyperparathyroidism was present. Using a conceptual approach, we suggest that a defect in the skeletal response to parathyroid hormone contributes to hyperparathyroidism in XLH. Finally, at the end of the review, abnormalities in renal phosphate transport that are sometimes found in patients with polyostotic fibrous dysplasia are discussed. PMID:19808223

  8. Disease, Models, Variants and Altered Pathways—Journeying RGD Through the Magnifying Glass

    PubMed Central

    Petri, Victoria; Hayman, G. Thomas; Tutaj, Marek; Smith, Jennifer R.; Laulederkind, Stan; Wang, Shur-Jen; Nigam, Rajni; De Pons, Jeff; Shimoyama, Mary; Dwinell, Melinda R.

    2015-01-01

    Understanding the pathogenesis of disease is instrumental in delineating its progression mechanisms and for envisioning ways to counteract it. In the process, animal models represent invaluable tools for identifying disease-related loci and their genetic components. Amongst them, the laboratory rat is used extensively in the study of many conditions and disorders. The Rat Genome Database (RGD—http://rgd.mcw.edu) has been established to house rat genetic, genomic and phenotypic data. Since its inception, it has continually expanded the depth and breadth of its content. Currently, in addition to rat genes, QTLs and strains, RGD houses mouse and human genes and QTLs and offers pertinent associated data, acquired through manual literature curation and imported via pipelines. A collection of controlled vocabularies and ontologies is employed for the standardized extraction and provision of biological data. The vocabularies/ontologies allow the capture of disease and phenotype associations of rat strains and QTLs, as well as disease and pathway associations of rat, human and mouse genes. A suite of tools enables the retrieval, manipulation, viewing and analysis of data. Genes associated with particular conditions or with altered networks underlying disease pathways can be retrieved. Genetic variants in humans or in sequenced rat strains can be searched and compared. Lists of rat strains and species-specific genes and QTLs can be generated for selected ontology terms and then analyzed, downloaded or sent to other tools. From many entry points, data can be accessed and results retrieved. To illustrate, diabetes is used as a case study to initiate and embark upon an exploratory journey. PMID:27602200

  9. Patients' journeys to a narcolepsy diagnosis: a physician survey and retrospective chart review.

    PubMed

    Carter, Lawrence P; Acebo, Christine; Kim, Ann

    2014-05-01

    Narcolepsy is a lifelong disorder with potentially debilitating symptoms. Obtaining an accurate diagnosis often requires multiple tests and physician visits. This report describes results from an online, quantitative, company-sponsored survey in which physicians provided information from the charts of their patients with narcolepsy. Neurologists, pulmonologists, psychiatrists, and other specialists who were board certified in sleep medicine; had 2 to 30 years of clinical experience; and treated ≥ 5 narcolepsy patients per month were invited to complete ≤ 6 surveys using charts of patients who were treated for narcolepsy in the last 6 months. Data from 252 patients were collected from 77 physicians. Patients were predominantly male (55%), white (67%), and had a median age of 38 years (range: 12-83 years). Referral to the respondent physician was common, mainly from primary care physicians. The most common initial symptoms were excessive daytime sleepiness (91%), trouble staying awake during the day (44%), and trouble concentrating/functioning during the day (43%). Overall, initial symptoms were of at least moderate severity in 85% of patients. Most patients completed overnight polysomnography (83%), a Multiple Sleep Latency Test (76%), and/or the Epworth Sleepiness Scale (62%). The median time from patient-reported symptom onset to diagnosis was 22 months (range: 0-126 months); at least half saw ≥ 2 providers before being diagnosed; and 60% of patients had previously been misdiagnosed with other disorders, including depression (31%), insomnia (18%), and/or obstructive sleep apnea (13%). In this study, the journey to a narcolepsy diagnosis required evaluation by multiple physicians and took nearly 2 years in 50% of patients, and > 5 years in 18%. These data highlight the need for increased awareness of the signs and symptoms of narcolepsy. PMID:24918805

  10. High Altitude Journeys, Flights and Hypoxia: Any Role for Disease Flares in IBD Patients?

    PubMed

    Vavricka, Stephan R; Rogler, Gerhard; Biedermann, Luc

    2016-01-01

    The importance of environmental factors in the pathogenesis including their disease-modifying potential are increasingly recognized in inflammatory bowel disease (IBD) patients, largely driven by the perception that the prevalence and incidence of IBD are on the rise within the last few years, especially in non-western countries. One of those factors is believed to be hypoxia. The role of hypoxia as a modifying or even causative factor in the genesis and maintenance of inflammation has been increasingly elucidated in recent years. Hypoxia is believed to be a main inducing factor of inflammation. This has been studied in different animal experiments as well as in humans exposed to hypoxia. In several studies - mainly in mice - animals exposed to short-term hypoxia accumulated inflammatory cells in multiple organs and showed elevated cytokines in the blood. Comparable studies were performed in humans, mainly in healthy mountaineers. Recently, we reported on the association between IBD flare-up episodes and antecedent journeys to high-altitude region and aircraft travels. According to these findings, we concluded that flights and stays at high altitudes of >2,000 mg are a risk factor for increased disease activity in IBD. To evaluate the potential influence of hypoxia on the course of IBD on a biomolecular level and to test the effects of hypoxia under standardized conditions, we initiated a prospective and controlled investigation in both healthy controls and IBD patients in stable remission. The study participants underwent a 3-hour exposure to hypoxic conditions simulating an altitude of 4,000 m above sea level in a hyperbaric pressure chamber and clinical parameters as well as blood and stool samples were collected at several time points. The first results of this study are expected in the near future. PMID:26981864

  11. Attaining ISO 15189 accreditation through SLMTA: A journey by Kenya’s National HIV Reference Laboratory

    PubMed Central

    Gachuki, Thomas; Sewe, Risper; Mwangi, Jane; Turgeon, David; Garcia, Mary; Luman, Elizabeth T.; Umuro, Mamo

    2015-01-01

    Background The National HIV Reference Laboratory (NHRL) serves as Kenya’s referral HIV laboratory, offering specialised testing and external quality assessment, as well as operating the national HIV serology proficiency scheme. In 2010, the Kenya Ministry of Health established a goal for NHRL to achieve international accreditation. Objectives This study chronicles the journey that NHRL took in pursuit of accreditation, along with the challenges and lessons learned. Methods NHRL participated in the Strengthening Laboratory Management Toward Accreditation (SLMTA) programme from 2010–2011. Improvement projects were undertaken to address gaps in the 12 quality system essentials through development of work plans, team formation, training and mentorship of personnel. Audits were conducted and the scores used to track progress along a five-star grading scale. Standard quality indicators (turn-around time, specimen rejection rates and service interruptions) were measured. Costs of improvement projects and accreditation were estimated based on expenditures. Results NHRL scored 45% (zero stars) at baseline in March 2010 and 95% (five stars) after programme completion in October 2011; in 2013 it became the first public health laboratory in Kenya to attain ISO 15189 accreditation. From 2010–2013, turn-around times decreased by 50% – 95%, specimen rejections decreased by 93% and service interruptions dropped from 15 to zero days. Laboratory expenditures associated with achieving accreditation were approximately US $36 500. Conclusion International accreditation is achievable through SLMTA, even for a laboratory with limited initial quality management systems. Key success factors were dedication to a shared goal, leadership commitment, team formation and effective mentorship. Countries wishing to achieve accreditation must ensure adequate funding and support. PMID:26753130

  12. Love stories: understanding the caring journeys of aged Greek-Australian carers.

    PubMed

    Horsfall, Debbie; Blignault, Ilse; Perry, Astrid; Antonopoulos, Penny

    2016-03-01

    This article documents the findings of a short-term longitudinal study that explored the caring journeys of aged Greek carers providing in-home care for their spouse. Through a deeper understanding of carers' decisions and decision-making and insights from service providers and community leaders, we aimed to inform policy makers, service managers and providers about how to develop and promote culturally appropriate support services, and negotiate them with carers and care recipients in a timely way. Initially, we conducted three focus groups and one follow-up forum with service providers and Greek community leaders. Then, over a 6-month period, we conducted two in-home interviews and two telephone interviews with 12 older Greek carers. We sought to understand factors influencing carers' decision-making regarding service uptake, and we provided information about services as required. Through our thematic analysis, we found that most carers wanted to remain as independent as possible and to avoid forced separation from the one they loved, through institutionalisation. They placed great value on their caring role which, while a struggle at times, gave them a sense of meaning, purpose and belonging. We also found that carers had great resourcefulness, strength and competence. They were all in long-term relationships, had negotiated coming to a foreign country and establishing themselves and were now in the process of negotiating old age and increasing frailty while at the same time providing care and support to family and friends. Our findings suggest that services need to be communicated in ways which support what carers value, not on outdated assumptions about cultural groups, otherwise providers will perpetuate exclusion. We propose an outreach in-home service model with an emphasis on ageing well and staying at home. This model of service provision is a model of care which emphasises relationships and community, and seeks to build social and cultural capital. PMID

  13. A classification of user-generated content into consumer decision journey stages.

    PubMed

    Vázquez, Silvia; Muñoz-García, Óscar; Campanella, Inés; Poch, Marc; Fisas, Beatriz; Bel, Nuria; Andreu, Gloria

    2014-10-01

    In the last decades, the availability of digital user-generated documents from social media has dramatically increased. This massive growth of user-generated content has also affected traditional shopping behaviour. Customers have embraced new communication channels such as microblogs and social networks that enable them not only just to talk with friends and acquaintances about their shopping experience, but also to search for opinions expressed by complete strangers as part of their decision making processes. Uncovering how customers feel about specific products or brands and detecting purchase habits and preferences has traditionally been a costly and highly time-consuming task which involved the use of methods such as focus groups and surveys. However, the new scenario calls for a deep assessment of current market research techniques in order to better interpret and profit from this ever-growing stream of attitudinal data. With this purpose, we present a novel analysis and classification of user-generated content in terms of it belonging to one of the four stages of the Consumer Decision Journey Court et al. (2009) (i.e. the purchase process from the moment when a customer is aware of the existence of the product to the moment when he or she buys, experiences and talks about it). Using a corpus of short texts written in English and Spanish and extracted from different social media, we identify a set of linguistic patterns for each purchase stage that will be then used in a rule-based classifier. Additionally, we use machine learning algorithms to automatically identify business indicators such as the Marketing Mix elements McCarthy and Brogowicz (1981). The classification of the purchase stages achieves an average precision of 74%. The proposed classification of texts depending on the Marketing Mix elements expressed achieved an average precision of 75% for all the elements analysed. PMID:24996448

  14. Guillain–Barré syndrome and anti-ganglioside antibodies: a clinician-scientist’s journey

    PubMed Central

    YUKI, Nobuhiro

    2012-01-01

    Guillain–Barré syndrome (GBS) is the most frequent cause of acute flaccid paralysis. Having seen my first GBS patient in 1989, I have since then dedicated my time in research towards understanding the pathogenesis of GBS. Along with several colleagues, we identified IgG autoantibodies against ganglioside GM1 in two patients with GBS subsequent to Campylobacter jejuni enteritis. We proceeded to demonstrate molecular mimicry between GM1 and bacterial lipo-oligosaccharide of C. jejuni isolated from a patient with GBS. Our group then established a disease model for GBS by sensitization with GM1 or GM1-like lipo-oligosaccharide. With this, a new paradigm that carbohydrate mimicry can cause autoimmune disorders was demonstrated, making GBS the first proof of molecular mimicry in autoimmune disease. Patients with Fisher syndrome, characterized by ophthalmoplegia and ataxia, can develop the disease after an infection by C. jejuni. We showed that the genetic polymorphism of C. jejuni sialyltransferase, an enzyme essential to the biosynthesis of ganglioside-like lipo-oligosaccharides determines whether patients develop GBS or Fisher syndrome. This introduces another paradigm that microbial genetic polymorphism can determine the clinical phenotype of human autoimmune diseases. Similarities between the clinical presentation of Fisher syndrome and Bickerstaff brainstem encephalitis have caused debate as to whether they are in fact the same disease. We demonstrated that IgG anti-GQ1b antibodies were common to both, suggesting that they are part of the same disease spectrum. We followed this work by clarifying the nosological relationship between the various clinical presentations within the anti-GQ1b antibody syndrome. In this review, I wanted to share my journey from being a clinician to a clinician-scientist in the hopes of inspiring younger clinicians to follow a similar path. PMID:22850724

  15. Disease, Models, Variants and Altered Pathways-Journeying RGD Through the Magnifying Glass.

    PubMed

    Petri, Victoria; Hayman, G Thomas; Tutaj, Marek; Smith, Jennifer R; Laulederkind, Stan; Wang, Shur-Jen; Nigam, Rajni; De Pons, Jeff; Shimoyama, Mary; Dwinell, Melinda R

    2016-01-01

    Understanding the pathogenesis of disease is instrumental in delineating its progression mechanisms and for envisioning ways to counteract it. In the process, animal models represent invaluable tools for identifying disease-related loci and their genetic components. Amongst them, the laboratory rat is used extensively in the study of many conditions and disorders. The Rat Genome Database (RGD-http://rgd.mcw.edu) has been established to house rat genetic, genomic and phenotypic data. Since its inception, it has continually expanded the depth and breadth of its content. Currently, in addition to rat genes, QTLs and strains, RGD houses mouse and human genes and QTLs and offers pertinent associated data, acquired through manual literature curation and imported via pipelines. A collection of controlled vocabularies and ontologies is employed for the standardized extraction and provision of biological data. The vocabularies/ontologies allow the capture of disease and phenotype associations of rat strains and QTLs, as well as disease and pathway associations of rat, human and mouse genes. A suite of tools enables the retrieval, manipulation, viewing and analysis of data. Genes associated with particular conditions or with altered networks underlying disease pathways can be retrieved. Genetic variants in humans or in sequenced rat strains can be searched and compared. Lists of rat strains and species-specific genes and QTLs can be generated for selected ontology terms and then analyzed, downloaded or sent to other tools. From many entry points, data can be accessed and results retrieved. To illustrate, diabetes is used as a case study to initiate and embark upon an exploratory journey. PMID:27602200

  16. A Modern Explorer's Journey - using events for innovative multipurpose educational outreach

    NASA Astrophysics Data System (ADS)

    Lilja Bye, Bente

    2014-05-01

    Earth observations are important across the specter of geo-sciences. The Group on Earth Observations (GEO) is coordinating efforts to build a Global Earth Observation System of Systems, or GEOSS. The lack of dedicated funding to support specific Science &Technology activities in support of GEOSS is one of the most important obstacles to engaging the Science &Technology communities in its implementation. Finding resources to outreach and capacity building is likewise a challenge. The continuation of GEO and GEOSS rely on political support which again is influenced by public opinions. The GEO Ministerial Summit in 2014 was an event that both needed visibility and represented an opportunity to mobilize the GEO community in producing outreach and educational material. Through the combined resources from two of GEO tasks in the GEO work plan, a multipurpose educational outreach project was planned and executed. This project addressed the following issues: How can the GEO community mobilize resources for its work plan projects in the Societal Benefit Area Water? How can we produce more educational and capacity building material? How can the GEO community support the GEO secretariat related to public relations (material and otherwise) Based on activities described in the GEO work plan, a showcase video and online campaign consisting on a series of webinars were developed and produced. The video and webinars were linked through a common reference: the water cycle. Various aspects of the water cycle ranging from general to more technical and scientific education were covered in the webinars, while the video called A Modern Explorer's Journey focused on story telling with a more emotional appeal. The video was presented to the Ministers at the GEO Ministerial Summit and distributed widely to the GEO community and through social media and articles (as embedded YouTube and more). A discussion of challenges and successes of this event-based educational outreach project will be

  17. "Does a Spider Have Fur"?: A Teacher's Journey in Building the Confidence to Blend the English Language Learning of ESL Students with Inquiry-Based Science

    ERIC Educational Resources Information Center

    Zeegers, Yvonne; McKinnon, Heather

    2012-01-01

    This paper describes one aspect of an ESL teacher's journey, in which her voluntary involvement in a series of science-based professional learning events inspired her to use language-based objectives to develop and teach an integrated unit of work with ESL students. Her willingness to modify her usual pedagogical practice and the inspiration she…

  18. Journeys of Transformation: A Statewide Effort by Mathematics and Science Professors To Improve Student Understanding. Case Reports from Participants in the Maryland Collaborative for Teacher Preparation.

    ERIC Educational Resources Information Center

    Gardner, Maureen B., Ed.

    This document presents the Maryland Collaborative for Teacher Preparation (MCTP) faculty's reviews on instructional issues of different disciplines. Contents include: (1) "The Maryland Collaborative for Teacher Preparation"; (2) "Guiding Principles: New Thinking in Mathematics and Science Teaching"; (3) "Introduction: Parallel Journeys of Risk and…

  19. "The Way to a Man's Heart." Journey and War Metaphors. Metaphorical Conceptualisations of the Western Romance Model in English and Spanish.

    ERIC Educational Resources Information Center

    Lopez, Maria Angeles Navarrete

    2001-01-01

    This paper examines two examples of the Western model of romance in English and Spanish discourse: the English metaphor, "the (best) way to a man's heart is through his stomach" (journey metaphor) and its Spanish counterpart, "Al hombre se le conquista por el estomago" (war metaphor). Both central metaphors entail a number of perceptual,…

  20. A Community College Instructor's Reflective Journey toward Developing Pedagogical Content Knowledge for Nature of Science in a Non-Majors Undergraduate Biology Course

    ERIC Educational Resources Information Center

    Krajewski, Sarah J.; Schwartz, Renee

    2014-01-01

    Research supports an explicit-reflective approach to teaching about nature of science (NOS), but little is reported on teachers' journeys as they attempt to integrate NOS into everyday lessons. This participatory action research paper reports the challenges and successes encountered by an in-service teacher, Sarah, implementing NOS for the…

  1. Transitioning to and Sustaining District-Wide Inclusive Services: A 7-Year Study of a District's Ongoing Journey and Its Accompanying Complexities

    ERIC Educational Resources Information Center

    Ryndak, Diane Lea; Reardon, Ric; Benner, Susan R.; Ward, Theresa

    2007-01-01

    This case study describes the journey of one school district as it focused for 5 years on affecting district-wide systemic change related to inclusive education for all students with disabilities, including those with severe disabilities. Information is provided about the district's efforts across 5 years, and data are provided across those 5 and…

  2. Restoring a Ruptured Relationship: Barnard College's Caryl Phillips' Senior English Seminar Focuses on Broken International Connections and Culminates with a Trans-Atlantic Journey

    ERIC Educational Resources Information Center

    Keels, Crystal L.

    2004-01-01

    Millions of African people who were captured, kidnapped and shackled for sale as part of the trans-Atlantic slave trade first passed through Cape Coast Castle in Ghana, West Africa. They stepped through the doorway that set them on a horrifying journey across the Atlantic Ocean. Men, women and children were taken by force, leaving their loved…

  3. One Educational Technology Colleague's Journey from Dotcom Leadership to University E-Learning Systems Leadership: Merging Design Principles, Systemic Change and Leadership Thinking

    ERIC Educational Resources Information Center

    Chow, Anthony S.

    2013-01-01

    This paper describes my journey from instructional technology professional and doctoral student to instructional technology leader and tenure-track faculty member. I reflect on 15 years of application, in government, industry, and higher education, of what I learned in the classroom from some of the giants of the field (Wager, Morgan, Kaufman,…

  4. Recovery Journeys of Counselors and Clients: A Case Study of the Therapeutic Alliance in a Drug Treatment and Rehabilitation Center in Malaysia

    ERIC Educational Resources Information Center

    Amat, Mohamad Isa

    2013-01-01

    The therapeutic alliance is a significant research area in counseling. The understanding of the therapeutic alliance, particularly in drug treatment settings helps counselors and clients to increase the treatment outcomes and its treatment process. The present study investigated the journeys of recovering counselors and clients in a private…

  5. Single-molecule paleoenzymology probes the chemistry of resurrected enzymes

    PubMed Central

    Perez-Jimenez, Raul; Inglés-Prieto, Alvaro; Zhao, Zi-Ming; Sanchez-Romero, Inmaculada; Alegre-Cebollada, Jorge; Kosuri, Pallav; Garcia-Manyes, Sergi; Kappock, T. Joseph; Tanokura, Masaru; Holmgren, Arne; Sanchez-Ruiz, Jose M.; Gaucher, Eric A.; Fernandez, Julio M.

    2011-01-01

    A journey back in time is possible at the molecular level by reconstructing proteins from extinct organisms. Here we report the reconstruction, based on sequence predicted by phylogenetic analysis, of seven Precambrian thioredoxin enzymes (Trx), dating back between ~1.4 and ~4 billion years (Gyr). The reconstructed enzymes are up to 32° C more stable than modern enzymes and the oldest show significantly higher activity than extant ones at pH 5. We probed their mechanisms of reduction using single-molecule force spectroscopy. From the force-dependency of the rate of reduction of an engineered substrate, we conclude that ancient Trxs utilize chemical mechanisms of reduction similar to those of modern enzymes. While Trx enzymes have maintained their reductase chemistry unchanged, they have adapted over a 4 Gyr time span to the changes in temperature and ocean acidity that characterize the evolution of the global environment from ancient to modern Earth. PMID:21460845

  6. From Model Rockets to Spacewalks: an Astronaut Physician’s Journey and the Science of the United States’ Space Program*

    PubMed Central

    Parazynski, Scott E

    2006-01-01

    From simple childhood dreams to their fulfillment, this presentation chronicles the author’s life journey from young model rocketteer through his medical training and eventual career as a NASA astronaut. Over the course of four Space Shuttle flights and a cumulative 6 weeks in space, including 20 hours of Extravehicular Activity (EVA, or spacewalking), this article describes a wide range of activities and scientific payloads that are representative of the unique and valuable science that can be accomplished in the microgravity of space. NASA’s efforts to develop inspection and repair capabilities in the aftermath of the Columbia tragedy are also covered, as are the nation’s plans for returning to the Moon and continuing on to Mars as part of the Vision for Space Exploration (VSE). PMID:18528479

  7. Immobility, battles, and the journey of feeling alive: women's metaphors of self-transformation through depression and recovery.

    PubMed

    Fullagar, Simone; O'Brien, Wendy

    2012-08-01

    Australian mental health services have responded to the problem of depression by adopting an early intervention and recovery orientation. Using qualitative research conducted in Australia with 80 women aged 20 to 75 years, we examine how participants invoked particular metaphors to construct meaning about the gendered experience of depression and recovery. We argue that women's stories of recovery provide a rich source of interpretive material to consider the everyday metaphors of recovery beyond clinical notions and linear models of personal change. We identified key metaphors women drew on to articulate the struggle of self-transformation through depression and recovery: the immobilizing effect of depression, recovery as a battle to control depression, and recovery as a journey of self-knowledge. Our findings might be useful for mental health professionals in a range of clinical contexts to reflect on the power of language for shaping how women interpret their experiences of recovery from depression. PMID:22609634

  8. From the Gut to the Brain: Journey and Pathophysiological Effects of the Food-Associated Trichothecene Mycotoxin Deoxynivalenol

    PubMed Central

    Maresca, Marc

    2013-01-01

    Mycotoxins are fungal secondary metabolites contaminating food and causing toxicity to animals and humans. Among the various mycotoxins found in crops used for food and feed production, the trichothecene toxin deoxynivalenol (DON or vomitoxin) is one of the most prevalent and hazardous. In addition to native toxins, food also contains a large amount of plant and fungal derivatives of DON, including acetyl-DON (3 and 15ADON), glucoside-DON (D3G), and potentially animal derivatives such as glucuronide metabolites (D3 and D15GA) present in animal tissues (e.g., blood, muscle and liver tissue). The present review summarizes previous and very recent experimental data collected in vivo and in vitro regarding the transport, detoxification/metabolism and physiological impact of DON and its derivatives on intestinal, immune, endocrine and neurologic functions during their journey from the gut to the brain. PMID:23612752

  9. Sentencing Male Sex Offenders Under the Age of 14: A Law Reform Advocacy Journey in Hong Kong.

    PubMed

    Ng, Wai-Ching Irene; Cheung, Monit; Ma, Anny Kit-Ying

    2015-01-01

    The common law presumption that a boy under the age of 14 is incapable of sexual intercourse has provoked controversial debates in Hong Kong. This article describes a 6-step advocacy journey to examine how community efforts have helped modify this law so that juvenile male sexual offenders under the age of 14 who have committed the crime of having sexual intercourse with underage females can be sentenced to receive appropriate treatment. Seven court cases provided by the magistrates' courts in Hong Kong were used in this advocacy effort for the removal of the presumption in July 2012. Although this effort has yet to reveal signs of effectiveness, it represents greater public awareness about providing rehabilitation appropriate for juvenile sex offenders through a formal sentence. Restorative justice, as opposed to retributive or punitive justice, places an emphasis on rehabilitation of the offender and restoration of victims to a place of wholeness. PMID:26061020

  10. Barriers to effective communication across the primary/secondary interface: examples from the ovarian cancer patient journey (a qualitative study).

    PubMed

    Farquhar, M C; Barclay, S I G; Earl, H; Grande, G E; Emery, J; Crawford, R A F

    2005-09-01

    Effective communication across the primary/secondary interface is vital for the planning and delivery of appropriate patient care throughout the cancer patient journey. This study describes GPs' views of the communication issues across the primary/secondary interface in relation to ovarian cancer patients using qualitative interviews with purposively sampled general practitioners (GPs) and an audit of hospital medical records of 30 deceased ovarian cancer patients. Issues raised by the GPs related to the content and format of communications, but of most concern was the tardiness. The time lag between dictation and typing letters ranged from 0 to 27 days, with a delay of up to 8 days for signing before transit through various mail systems to the GP. Three stages in the patient journey were characterized by particular issues: (1) in the pre-diagnostic and diagnostic stage was a need for prompt information regarding the results of tests and diagnoses, and clearer guidance on the use of tests and fast-track referrals; (2) in the active treatment phase, when GPs could lose touch with their patients, they needed effective communication in order to provide moral support and crisis management; and (3) when oncology withdrew and the focus of care switched back to the community for the terminal phase, GPs needed information to enable them to pick up the baton of care. There is a need to develop and evaluate interventions aimed at improving the content and speed of communications between secondary and primary care. Such interventions are likely to be complex and might include the greater use of telephone or fax for more selected communications, a review of secretarial support, the use of email, the development of GP designed proformas, the feasibility of patient/carer letter delivery options, nurse-led communication, universal electronic patient records, or a revisiting of the patient-held record. PMID:16098121

  11. Toxic Tourism: A New Itinerary for the Environmental Justice Movement.

    ERIC Educational Resources Information Center

    Di Chiro, Giovanna

    2001-01-01

    Tours of minority group neighborhoods show participants the effects of polluting industries that are disproportionately sited near them. The tours make people aware of this overt environmental racism and inspire them to take action. Such tours must be handled with tact, preferably by the affected communities themselves, to avoid voyeurism and…

  12. Geosciences help to protect human health: estimation of the adsorbed radiation doses while flight journeys, as important step to radiation risk assessment

    NASA Astrophysics Data System (ADS)

    Chernov, Anatolii; Shabatura, Olexandr

    2016-04-01

    Estimation of the adsorbed radiation dose while flight journeys is a complex problem, which should be solved to get correct evaluation of equivalent effective doses and radiation risk assessment. Direct measurements of the adsorbed dose in the aircrafts during regional flights (3-10 hours) has shown that the radiation in the plane may increase 10-15 times (to 2-4 mSv/h) compared to the values on the surface of the Earth (0.2-0.5 mSv/h). Results of instrumental research confirmed by the other investigations. It is a fact that adsorbed doses per year while flight journeys are less than doses from medical tests. However, while flight journeys passengers get the same doses as nuclear power plant staff, people in zones of natural radiation anomalies and so should be evaluated. According to the authors' research, flight journeys are safe enough, when solar activity is normal and if we fly under altitude of 18 km (as usual, while intercontinental flights). Most of people travel by plane not so often, but if flight is lasting in dangerous periods of solar activity (powerful solar winds and magnetic field storms), passengers and flight crew can adsorb great amount of radiation doses. People, who spend more than 500 hours in flight journeys (pilots, business oriented persons', government representatives, etc.) get amount of radiation, which can negatively influence on health and provoke diseases, such as cancer. Authors consider that problem actual and researches are still going on. It is revealed, that radiation can be calculated, using special equations. Great part of radiation depends on very variable outer-space component and less variable solar. Accurate calculations of doses will be possible, when we will take into account all features of radiation distribution (time, season of year and exact time of the day, duration of flight), technical features of aircraft and logistics of flight (altitude, latitude). Results of first attempts of radiation doses modelling confirmed

  13. Second space Christmas for ESA: Huygens to begin its final journey to Titan/ Media activities.

    NASA Astrophysics Data System (ADS)

    2004-12-01

    At 1.25 billion km from Earth, after a 7-year journey through the Solar system, ESA’s Huygens probe is about to separate from the Cassini orbiter to enter a ballistic trajectory toward Titan, the largest and most mysterious moon of Saturn, in order to dive into its atmosphere on 14 January. This will be the first man-made object to explore in-situ this unique environment, whose chemistry is assumed to be very similar to that of the early Earth just before life began, 3.8 billion years ago. The Cassini-Huygens pair, a joint mission conducted by NASA, ESA and the Italian space agency (ASI), was launched into space on 15 October 1997. With the help of several gravity assist manoeuvres during flybys of Venus, Earth and Jupiter, it took almost 7 years for the spacecraft to reach Saturn. The Cassini orbiter, carrying Huygens on its flank, entered an orbit around Saturn on 1 July 2004, and began to investigate the ringed planet and its moons for a mission that will last at least four years. The first distant flyby of Titan took place on 2-3 July 2004. It provided data on Titan's atmosphere which were confirmed by the data obtained during the first close flyby on 26 October 2004 at an altitude of 1174 km. These data were used to validate the entry conditions of the Huygens probe. A second close flyby of Titan by Cassini-Huygens at an altitude of 1200 km is scheduled on 13 December and will provide additional data to further validate the entry conditions of the Huygens probe. On 17 December the orbiter will be placed on a controlled collision course with Titan in order to release Huygens on the proper trajectory, and on 21 December (some dates and times are subject to minor adjustment for operational reasons, except the entry time on 14 January which is know to within an accuracy of under 2 minutes) all systems will be set up for separation and the Huygens timers will be set to wake the probe a few hours before its arrival at Titan. The Huygens probe is due to separate on

  14. Exploring Shamanic Journeying: Repetitive Drumming with Shamanic Instructions Induces Specific Subjective Experiences but No Larger Cortisol Decrease than Instrumental Meditation Music

    PubMed Central

    Gingras, Bruno; Pohler, Gerald; Fitch, W. Tecumseh

    2014-01-01

    Exposure to repetitive drumming combined with instructions for shamanic journeying has been associated with physiological and therapeutic effects, such as an increase in salivary immunoglobulin A. In order to assess whether the combination of repetitive drumming and shamanic instructions is specifically associated with these effects, we compared the effect of listening to either repetitive drumming or instrumental meditation music for 15 minutes on salivary cortisol concentration and on self-reported physiological and psychological states. For each musical style, two groups of participants were exposed to two conditions: instructions for shamanic journeying or relaxation instructions. A total of 39 participants (24 females) inexperienced in shamanic journeying completed the experiment. Salivary cortisol concentrations were measured before and after exposure to music. In addition, participants filled out a mood questionnaire before and after the experiment and completed a post experiment questionnaire on their experiences. A significant decrease in the concentration in salivary cortisol was observed across all musical styles and instructions, indicating that exposure to 15 minutes of either repetitive drumming or instrumental meditation music, while lying down, was sufficient to induce a decrease in cortisol levels. However, no differences were observed across conditions. Significant differences in reported emotional states and subjective experiences were observed between the groups. Notably, participants exposed to repetitive drumming combined with shamanic instructions reported experiencing heaviness, decreased heart rate, and dreamlike experiences significantly more often than participants exposed to repetitive drumming combined with relaxation instructions. Our findings suggest that the subjective effects specifically attributed to repetitive drumming and shamanic journeying may not be reflected in differential endocrine responses. PMID:24999623

  15. Exploring shamanic journeying: repetitive drumming with shamanic instructions induces specific subjective experiences but no larger cortisol decrease than instrumental meditation music.

    PubMed

    Gingras, Bruno; Pohler, Gerald; Fitch, W Tecumseh

    2014-01-01

    Exposure to repetitive drumming combined with instructions for shamanic journeying has been associated with physiological and therapeutic effects, such as an increase in salivary immunoglobulin A. In order to assess whether the combination of repetitive drumming and shamanic instructions is specifically associated with these effects, we compared the effect of listening to either repetitive drumming or instrumental meditation music for 15 minutes on salivary cortisol concentration and on self-reported physiological and psychological states. For each musical style, two groups of participants were exposed to two conditions: instructions for shamanic journeying or relaxation instructions. A total of 39 participants (24 females) inexperienced in shamanic journeying completed the experiment. Salivary cortisol concentrations were measured before and after exposure to music. In addition, participants filled out a mood questionnaire before and after the experiment and completed a post experiment questionnaire on their experiences. A significant decrease in the concentration in salivary cortisol was observed across all musical styles and instructions, indicating that exposure to 15 minutes of either repetitive drumming or instrumental meditation music, while lying down, was sufficient to induce a decrease in cortisol levels. However, no differences were observed across conditions. Significant differences in reported emotional states and subjective experiences were observed between the groups. Notably, participants exposed to repetitive drumming combined with shamanic instructions reported experiencing heaviness, decreased heart rate, and dreamlike experiences significantly more often than participants exposed to repetitive drumming combined with relaxation instructions. Our findings suggest that the subjective effects specifically attributed to repetitive drumming and shamanic journeying may not be reflected in differential endocrine responses. PMID:24999623

  16. Reimagining the Job of Leading Schools: Lessons from a 10-Year Journey

    ERIC Educational Resources Information Center

    Journal of Staff Development, 2010

    2010-01-01

    Quality leadership is a must in any important human pursuit, and education is no exception. While teachers have the most direct and obvious impact on student learning, the school leader is in the best position to ensure that excellent teaching and learning are not limited to single classrooms but spread throughout entire schools. Improving…

  17. From "At-Risk" to "At-Promise": A Three-Year Journey

    ERIC Educational Resources Information Center

    Coleman, J. Harrison

    2004-01-01

    Emily Spong Elementary School is a Pre-K-5 urban school in a high-poverty community, surrounded on three sides by public housing and with an enrollment of 250 black students, most of them from single-parent homes and many being raised by grandparents. The school has the highest Title I enrollment in the district.

  18. [Botanical journey of Josef A. Knapp in Galicia as a part of exploration of Austro-Hungarian Monarchy].

    PubMed

    Wysokińska, Beata

    2011-01-01

    Josef Armin Knapp (1843-1899) as Austrian botanist was interested in development of botanical knowledge of Austro-Hungarian Monarchy--his maternal country. Monarchy, during the long regency of emperor Franz Josef I, was multinational, very much diversified geographically territory. This large empire had included, among others, such countries as present Austria, Hungary, Slovakia, Croatia, Ukraine, Romania and the southern part of present Poland--previously known as Galicia. J. A. Knapp was interested in studying these parts of empire which were considered peripheries and less-known. It seems to have met the requirements of science, economy and administration of Vienna. J. A. Knapp in his large floristic researches had included explorations of considerable part of the Monarchy and had left an interesting scientific legacy. His research papers were results of botanical explorations in selected areas of the Monarchy--area of Nitra (currently a city in Slovakia), Slavonia (presently a land in Croatia) and Galicia (the historical area in the south of Poland). This article refers to the botanical journey of J. A. Knapp in Galicia in summer 1868. The main purpose of his journey was to visit and explore selected places in Galicia--the surroundings of Jaslo and Sanok towns and some specific areas within the Bieszczady Mountains, which are part of the Carpathians Mountains. Botanical researches in the Bieszczady Mountains provided by J. A. Knapp can be considered nowadays as very important and pioneering in that area. In the second part of XIX century this area was highly populated and the observed anthropogenic pressure applied to the nature was strong. Now, the area is considered a very valuable natural territory--since 1973 it has been occupied by the Bieszczady National Park--one of Polish national parks. J. A. Knapp had spent more than two months in Galicia thanks to the great hospitality of Polish people, especially botanists: A. Rehmann, I. R. Czerwiakowski, W. Jab

  19. My Journey as a Surgeon-Scientist Ten Years after Receiving the Inaugural Jacobson Promising Investigator Award.

    PubMed

    Longaker, Michael T

    2015-10-01

    The First Joan L and Julius H Jacobson Promising Investigator Awardee, Michael T Longaker MD, FACS In 2005, the research committee of the American College of Surgeons was tasked with selecting the recipient of a newly established award, "The Joan L and Julius H Jacobson Promising Investigator Award." According to the Jacobsons, the $30,000 award funded by Dr Jacobson should be given at least once every 2 years to a surgeon investigator at "the tipping point," who can demonstrate that his/her research shows the promise of leading to a significant contribution to the practice of surgery and patient safety. Every year, the research committee receives many excellent nominations and has the difficult task of selecting 1 awardee. In 2005, the awardee was a young promising investigator, Michael T Longaker, MD, FACS. Ten years later, Dr Longaker, a prominent researcher in the field of "scar formation," presents his journey in research and the impact of the Jacobson award on his career. Dr Longaker is now a national and international figure in the field of wound healing, tissue regeneration, and stem cell research. Kamal MF Itani, MD, FACS and Gail Besner, MD, FACS, on behalf of the Research Committee of the American College of Surgeons. PMID:26304185

  20. Mapping the journey from totipotency to lineage specification in the mouse embryo.

    PubMed

    Leung, Chuen Yan; Zernicka-Goetz, Magdalena

    2015-10-01

    Understanding the past is to understand the present. Mammalian life, with all its complexity comes from a humble beginning of a single fertilized egg cell. Achieving this requires an enormous diversification of cellular function, the majority of which is generated through a series of cellular decisions during embryogenesis. The first decisions are made as the embryo prepares for implantation, a process that will require specialization of extra-embryonic lineages while preserving an embryonic one. In this mini-review, we will focus on the mouse as a mammalian model and discuss recent advances in the decision making process of the early embryo. PMID:26343010

  1. Second space Christmas for ESA: Huygens to begin its final journey to Titan/ Media activities.

    NASA Astrophysics Data System (ADS)

    2004-12-01

    At 1.25 billion km from Earth, after a 7-year journey through the Solar system, ESA’s Huygens probe is about to separate from the Cassini orbiter to enter a ballistic trajectory toward Titan, the largest and most mysterious moon of Saturn, in order to dive into its atmosphere on 14 January. This will be the first man-made object to explore in-situ this unique environment, whose chemistry is assumed to be very similar to that of the early Earth just before life began, 3.8 billion years ago. The Cassini-Huygens pair, a joint mission conducted by NASA, ESA and the Italian space agency (ASI), was launched into space on 15 October 1997. With the help of several gravity assist manoeuvres during flybys of Venus, Earth and Jupiter, it took almost 7 years for the spacecraft to reach Saturn. The Cassini orbiter, carrying Huygens on its flank, entered an orbit around Saturn on 1 July 2004, and began to investigate the ringed planet and its moons for a mission that will last at least four years. The first distant flyby of Titan took place on 2-3 July 2004. It provided data on Titan's atmosphere which were confirmed by the data obtained during the first close flyby on 26 October 2004 at an altitude of 1174 km. These data were used to validate the entry conditions of the Huygens probe. A second close flyby of Titan by Cassini-Huygens at an altitude of 1200 km is scheduled on 13 December and will provide additional data to further validate the entry conditions of the Huygens probe. On 17 December the orbiter will be placed on a controlled collision course with Titan in order to release Huygens on the proper trajectory, and on 21 December (some dates and times are subject to minor adjustment for operational reasons, except the entry time on 14 January which is know to within an accuracy of under 2 minutes) all systems will be set up for separation and the Huygens timers will be set to wake the probe a few hours before its arrival at Titan. The Huygens probe is due to separate on

  2. [The Journey of a Surgeon Begins with a Camera-Holder].

    PubMed

    Li, Hui

    2016-06-20

    The techniques of thoracic surgery has undergone evolutionary changes, and currently video-assisted thoracic surgery (VATS) has already been or is going to be the predominant procedure of various thoracic surgeries. The safe and artistic VATS with high quality is closely associated with the cooperation of camera-holder and the surgeon. If an excellent thoracotomy is the result of perfect integral cooperation of the brain, eyes, hands and the body of the surgeon, the camera-holder in VATS procedure, then, is responsible for the eyes of both the surgeons and himself. This is more meticulous and difficult than that for a single person's brain, eyes, hands and body. Meanwhile, an excellent camera-holder will undoubtedly become an excellent surgeon in the foreseeable future. PMID:27335299

  3. More than what the eye can see: the emotional journey and experience of powerlessness of integrated care service users and their carers

    PubMed Central

    Boudioni, Markella; Hallett, Nina; Lora, Cristina; Couchman, Wendy

    2015-01-01

    Purpose This article presents the emotional journey and experience of powerlessness of integrated care service users and carers. Materials and methods The experiences of seven integrated care service users and carers affected by complex conditions in a London borough were captured as video stories. The integrated care service coordinated a system of health and social care: primary care, community matrons, social workers, and the voluntary sector. The service was designed to respond to identified cases of high-risk individuals with long-term, multiple, and age-related conditions needing preventive interventions. The video stories were analyzed by researchers in collaboration with service users using a visual thematic qualitative approach. This report is part of an independent analysis of the integrated care service evaluation that used the experience-based codesign model. Results The findings are presented in the respective contexts of people with complex conditions and their carers. The overwhelming feelings and emotions of both were loss of control and power throughout their emotional journey, with family carers adopting a protective attitude toward the patients. Their experience of powerlessness was variable throughout their emotional journey. They were affected more strongly when in need of extra help and support and while they were undergoing the process of receiving extra services. When they were receiving help and support outside and within hospitals, some participants were empowered, gaining skills and knowledge by being provided with the mechanisms to cope with their condition at present and in the future. Conclusion Feelings of powerlessness were very common among integrated care service users and their carers. Powerless/empowerment has been poorly investigated to date. Visual methods and collaborative visual analysis with service users have proved to be powerful methods too, but have been rarely reported. PMID:25848232

  4. Robert Feulgen Prize Lecture 1993. The journey of the insulin receptor into the cell: from cellular biology to pathophysiology.

    PubMed

    Carpentier, J L

    1993-09-01

    The data that we have reviewed indicate that insulin binds to a specific cell-surface receptor. The complex then becomes involved in a series of steps which lead the insulin-receptor complex to be internalized and rapidly delivered to endosomes. From this sorting station, the hormone is targeted to lysosomes to be degraded while the receptor is recycled back to the cell surface. This sequence of events presents two degrees of ligand specificity: (a) The first step is ligand-dependent and requires insulin-induced receptor phosphorylation of specific tyrosine residues. It consists in the surface redistribution of the receptor from microvilli where it preferentially localizes in its unoccupied form. (b) The second step is more general and consists in the association with clathrin-coated pits which represents the internalization gate common to many receptors. This sequence of events participates in the regulation of the biological action of the hormone and can thus be implicated in the pathophysiology of diabetes mellitus and various extreme insulin resistance syndromes, including type A extreme insulin resistance, leprechaunism, and Rabson-Mendehall syndrome. Alterations of the internalization process can result either from intrinsic abnormalities of the receptor or from more general alteration of the plasma membrane or of the cell metabolism. Type I diabetes is an example of the latter possibility, since general impairment of endocytosis could contribute to extracellular matrix accumulation and to an increase in blood cholesterol. Thus, better characterization of the molecular and cellular biology of the insulin receptor and of its journey inside the cell definitely leads to better understanding of disease states, including diabetes. PMID:8244769

  5. Bacterial genotoxins: The long journey to the nucleus of mammalian cells.

    PubMed

    Frisan, Teresa

    2016-03-01

    Bacterial protein genotoxins target the DNA of eukaryotic cells, causing DNA single and double strand breaks. The final outcome of the intoxication is induction of DNA damage responses and activation of DNA repair pathways. When the damage is beyond repair, the target cell either undergoes apoptosis or enters a permanent quiescent stage, known as cellular senescence. In certain instances, intoxicated cells can survive and proliferate. This event leads to accumulation of genomic instability and acquisition of malignant traits, underlining the carcinogenic potential of these toxins. The toxicity is dependent on the toxins' internalization and trafficking from the extracellular environment to the nucleus, and requires a complex interaction with several cellular membrane compartments: the plasma membrane, the endosomes, the trans Golgi network and the endoplasmic reticulum, and finally the nucleus. This review will discuss the current knowledge of the bacterial genotoxins internalization pathways and will highlight the issues that still remain unanswered. This article is part of a Special Issue entitled: Pore-Forming Toxins edited by Mauro Dalla Serra and Franco Gambale. PMID:26299818

  6. Traversing the Cell: Agrobacterium T-DNA’s Journey to the Host Genome

    PubMed Central

    Gelvin, Stanton B.

    2012-01-01

    The genus Agrobacterium is unique in its ability to conduct interkingdom genetic exchange. Virulent Agrobacterium strains transfer single-strand forms of T-DNA (T-strands) and several Virulence effector proteins through a bacterial type IV secretion system into plant host cells. T-strands must traverse the plant wall and plasma membrane, traffic through the cytoplasm, enter the nucleus, and ultimately target host chromatin for stable integration. Because any DNA sequence placed between T-DNA “borders” can be transferred to plants and integrated into the plant genome, the transfer and intracellular trafficking processes must be mediated by bacterial and host proteins that form complexes with T-strands. This review summarizes current knowledge of proteins that interact with T-strands in the plant cell, and discusses several models of T-complex (T-strand and associated proteins) trafficking. A detailed understanding of how these macromolecular complexes enter the host cell and traverse the plant cytoplasm will require development of novel technologies to follow molecules from their bacterial site of synthesis into the plant cell, and how these transferred molecules interact with host proteins and sub-cellular structures within the host cytoplasm and nucleus. PMID:22645590

  7. Biofilm, pathogenesis and prevention--a journey to break the wall: a review.

    PubMed

    Gupta, Priya; Sarkar, Subhasis; Das, Bannhi; Bhattacharjee, Surajit; Tribedi, Prosun

    2016-01-01

    Biofilms contain group(s) of microorganisms that are found to be associated with the biotic and abiotic surfaces. Biofilms contain either homogenous or heterogeneous populations of bacteria which remain in the matrix made up of extracellular polymeric substances secreted by constituent population of the biofilm. Biofilms can be either single or multilayered. Biofilms are an increasing issue of concern that is gaining importance with each passing day. Due to the ubiquitous nature of biofilms, it is difficult to eradicate them. It has been seen that many infectious diseases harbour biofilms of bacterial pathogens as the reservoir of persisting infections which can prove fatal at times. The presence of biofilms can be seen in diseases like endocarditis, cystic fibrosis, periodontitis, rhinosinusitis and osteomyelitis. The presence of biofilms has been mostly seen in medical implants and urinary catheters. Various signalling events including two-component signalling, extra cytoplasmic function and quorum sensing are involved in the formation of biofilms. The presence of an extracellular polymeric matrix in biofilms makes it difficult for the antimicrobials to act on them and make the bacteria tolerant to antibiotics and other drugs. The aim of this review was to discuss about the basic formation of a biofilm, various signalling cascades involved in biofilm formation, possible mechanisms of drug resistance in biofilms and recent therapeutic approaches involved in successful eradication of biofilms. PMID:26377585

  8. Repetition suppression to faces in the fusiform face area: A personal and dynamic journey.

    PubMed

    Henson, Richard N

    2016-07-01

    I review a number of fMRI studies that investigate the effects of repeating faces on responses in the fusiform face area (FFA). These studies show that repetition suppression (RS), as well as repetition enhancement (RE), are sensitive to multiple factors, including pre-existing stimulus representations, cognitive task, lag between repetitions and spatial attention. Parallel EEG studies provide additional constraints on the timing of these repetition effects. Together, the results suggest that RS is not a unitary phenomenon, but likely subsumes multiple mechanisms that operate under different conditions. These mechanisms of course need to relate to single-cell data and known physiological mechanisms; but to make further progress, I believe we need dynamical neural network models that relate these mechanisms to the properties of neural populations that are measured by fMRI and EEG data. One example model is sketched, in which RS reflects an acceleration of neural dynamics, owing to reduced prediction error within a recurrent visual processing hierarchy. PMID:26615518

  9. An unexpected journey: conceptual evolution of mechanoregulated potassium transport in the distal nephron.

    PubMed

    Carrisoza-Gaytan, Rolando; Carattino, Marcelo D; Kleyman, Thomas R; Satlin, Lisa M

    2016-02-15

    Flow-induced K secretion (FIKS) in the aldosterone-sensitive distal nephron (ASDN) is mediated by large-conductance, Ca(2+)/stretch-activated BK channels composed of pore-forming α-subunits (BKα) and accessory β-subunits. This channel also plays a critical role in the renal adaptation to dietary K loading. Within the ASDN, the cortical collecting duct (CCD) is a major site for the final renal regulation of K homeostasis. Principal cells in the ASDN possess a single apical cilium whereas the surfaces of adjacent intercalated cells, devoid of cilia, are decorated with abundant microvilli and microplicae. Increases in tubular (urinary) flow rate, induced by volume expansion, diuretics, or a high K diet, subject CCD cells to hydrodynamic forces (fluid shear stress, circumferential stretch, and drag/torque on apical cilia and presumably microvilli/microplicae) that are transduced into increases in principal (PC) and intercalated (IC) cell cytoplasmic Ca(2+) concentration that activate apical voltage-, stretch- and Ca(2+)-activated BK channels, which mediate FIKS. This review summarizes studies by ourselves and others that have led to the evolving picture that the BK channel is localized in a macromolecular complex at the apical membrane, composed of mechanosensitive apical Ca(2+) channels and a variety of kinases/phosphatases as well as other signaling molecules anchored to the cytoskeleton, and that an increase in tubular fluid flow rate leads to IC- and PC-specific responses determined, in large part, by the cell-specific composition of the BK channels. PMID:26632600

  10. Ascribing Functions to Genes: Journey Towards Genetic Improvement of Rice Via Functional Genomics.

    PubMed

    Mustafiz, Ananda; Kumari, Sumita; Karan, Ratna

    2016-06-01

    Rice, one of the most important cereal crops for mankind, feeds more than half the world population. Rice has been heralded as a model cereal owing to its small genome size, amenability to easy transformation, high synteny to other cereal crops and availability of complete genome sequence. Moreover, sequence wealth in rice is getting more refined and precise due to resequencing efforts. This humungous resource of sequence data has confronted research fraternity with a herculean challenge as well as an excellent opportunity to functionally validate expressed as well as regulatory portions of the genome. This will not only help us in understanding the genetic basis of plant architecture and physiology but would also steer us towards developing improved cultivars. No single technique can achieve such a mammoth task. Functional genomics through its diverse tools viz. loss and gain of function mutants, multifarious omics strategies like transcriptomics, proteomics, metabolomics and phenomics provide us with the necessary handle. A paradigm shift in technological advances in functional genomics strategies has been instrumental in generating considerable amount of information w.r.t functionality of rice genome. We now have several databases and online resources for functionally validated genes but despite that we are far from reaching the desired milestone of functionally characterizing each and every rice gene. There is an urgent need for a common platform, for information already available in rice, and collaborative efforts between researchers in a concerted manner as well as healthy public-private partnership, for genetic improvement of rice crop better able to handle the pressures of climate change and exponentially increasing population. PMID:27252584

  11. ESO takes the public on an astronomical journey "Around the World in 80 Telescopes"

    NASA Astrophysics Data System (ADS)

    2009-03-01

    Year of Astronomy 2009. 100HA is on track to be the largest single science public outreach event ever, with more than 1500 events registered in over 130 countries. 100HA will take place over four days and nights, from 2-5 April 2009. It is a worldwide celebration composed of a broad range of activities aimed at involving the public. During this period, people from around the globe will share the experience and wonder of observing the sky. For many, it will be their first glimpse of the marvels of the heavens through a telescope. For others, it is the perfect opportunity to impart their knowledge and excitement, helping unveil the cosmos to fresh and eager eyes. Astronomers at ESO are also organising local public events near their headquarters in Garching, near Munich. In the Munich city centre, ESO astronomers, together with colleagues from the Excellence Cluster Universe, will share their views of the cosmos with members of the public. ESO in Chile is also participating in a series of events to celebrate the 100 Hours of Astronomy. In Antofagasta, an exhibition by international and local astrophotographers will be unveiled at the main mall in the city. Star parties will be organised for the public in the desert outside Antofagasta, in coordination with the local university UCN. In Santiago, ESO is offering, along with other international observatories and the Chilean astronomical community, a complete set of programmes, including public talks, night observations and interactive exhibitions. In San Pedro de Atacama, the ALMA project will install an inflatable planetarium for the local community, and astronomy workshops and star parties will be offered to the public. More information ESO, the European Southern Observatory, is the foremost intergovernmental astronomy organisation in Europe. It is supported by 14 countries: Austria, Belgium, the Czech Republic, Denmark, France, Finland, Germany, Italy, the Netherlands, Portugal, Spain, Sweden, Switzerland and the United

  12. A Personal Journey into Gay Marriage in a Heteronormative Society: Or...How Many Times Do We Have to Get "Married" in Order to Have Our Rights in the USA?

    ERIC Educational Resources Information Center

    King, Kathleen P.

    2010-01-01

    Understanding the continuing struggle for lesbian, gay, bisexual, transgender, and queer (LGBTQ) equality can be difficult for people who have not experienced the issues firsthand. This brief article describes the journey of one woman and her female partner as they repeatedly seek to make their lifetime commitment legal in the USA. Readers will…

  13. A Descriptive Case Study of the Perceptions and Use of Adventist Edge: An Initiative Developed in Response to the North American Division of Seventh-Day Adventists' Document, "Journey to Excellence"

    ERIC Educational Resources Information Center

    Forbes, Pamela C.

    2011-01-01

    Problem. The Southern Union started the Adventist EDGE initiative as an action plan in response to the North American Division's document, "Journey to Excellence." The Adventist EDGE became a comprehensive educational reform initiative. However, there were different ideas on how the innovation should look when in action in the schools, and these…

  14. Journey to the Outdoors

    ERIC Educational Resources Information Center

    Boyd, Margaret

    2013-01-01

    A keen personal interest in natural history, involvement in environmental organisations, and experience, first as a secondary biology teacher and later as a field teacher, means that this author has spent many years working outdoors. Any part of the curriculum involving ecological concepts would lead her to open the door and go outside. She…

  15. A Leadership Journey

    ERIC Educational Resources Information Center

    Knudsen, Gene

    2007-01-01

    This article features Ellen Minette, principal of Heidelberg Middle School in Heidelberg, Germany. Minette attended 13 schools before she graduated from high school. Her father, an Air Force pilot who served in the Korean War and who was a part of the Berlin Airlift, was deployed much of the time as they moved from one posting to another. Growing…

  16. The Mythic Journey.

    ERIC Educational Resources Information Center

    Sisk, Dorothy

    2001-01-01

    This article describes a literature-based unit on mythology taught to 85 gifted middle school students. It identifies project objectives, gives examples of the grouping of myths according to broad themes, and provides more detail about one of the themes, assessment activities, and long-term effects of the project. (Contains six references.) (DB)

  17. A Teaching Journey

    ERIC Educational Resources Information Center

    Ratzel, Marsha

    2013-01-01

    The author of this article, a middle school science teacher, reflects on her teaching profession and how she connected to other teachers which helped fuel her students' love of learning. She describes her traditional teaching practice and the facilities of her school's middle science laboratory facilities. She explains how social media…

  18. Journey: The Gang Alternative.

    ERIC Educational Resources Information Center

    Castellaw, Bonni

    1992-01-01

    An intensive three-day program at the Pines Catholic Camp, followed by weekly support meetings, aim to prevent Dallas teens from turning to gang participation. Program components include personal goal setting, commitment to a code of conduct, and physical activities that promote group unity and positive peer pressure. (SV)

  19. Journey to Japan

    ERIC Educational Resources Information Center

    Godfrey, Lorraine

    1978-01-01

    Create a variety of activities related to the country you are studying--Japan, for example--and arrange them by such subjects as art, games, creative writing, maps, dress and greetings. These activities can be tied in with classroom learning centers or stations. Here students make passports, learn about traditional styles of dress in Japan, learn…

  20. Annie's Journey to Healing

    ERIC Educational Resources Information Center

    Kreisle, Beate

    2008-01-01

    Ongoing traumatising life events can often cause a person to the have physical or emotional characteristics of one who is mentally disabled or autistic, making it easy to form a wrong first impression. This article presents the story of one such person in a Positive Peer Culture program in a group treatment facility in Germany. In Positive Peer…

  1. Another RSNA Malaysian journey.

    PubMed

    Cobb, R J

    1995-07-01

    The RSNA International Visiting Professor program gave us an opportunity to live in a different and exciting country for 6 months. We had adequate travel opportunities to visit in Southeast Asia. Most of all, the feeling of appreciation and accomplishment we received from the master students as exemplified by their concern for us made our adventure extremely rewarding. For example, on the day of departure about half the class came to the airport to bid us farewell. This gesture, as well as several farewell parties in our honor, was certainly very gratifying. I enthusiastically recommend the opportunity afforded by the RSNA Visiting Professor program, and, specifically, I am enthusiastic about the program at Universiti Malaya. PMID:7784587

  2. Our Great Journey

    ERIC Educational Resources Information Center

    Fearon, Bec

    2008-01-01

    For nearly two years a group of 12 people, who are service-users from L8 and Fazakerley Resource Centres for adults with learning disabilities, had been working with artist Leo Fitzmaurice on WILD!, a project investigating what contemporary art meant to them. Part of the Bluecoat Connect programme, run with support from Liverpool Biennial and…

  3. A Fruitful Journey

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This overview map made from images taken by the camera on the Mars Global Surveyor orbiter illustrates the path that the Mars Exploration Rover Opportunity has taken from its first sol on the red planet through its 91st sol. After thoroughly examining its 'Eagle Crater' landing-site, the rover moved onto the plains of Meridiani Planum, stopping to examine a curious trough and a target within it called 'Anatolia.' Following that, Opportunity approached and remotely studied the rocky dish called 'Fram Crater.' As of its 91st sol (April 26, 2004), the rover has traveled about 811 meters (.5 miles) and currently sits about 160 meters (525 feet) from the rim of its next target, 'Endurance Crater.'

  4. A Leadership Journey

    ERIC Educational Resources Information Center

    Hancock, Michele; Lamendola, Barbara

    2005-01-01

    The road to improvement has taken the staff of a high-poverty urban school from isolation to collaboration. The innovations that were developed based on the basis of the collective analysis of school wide requirements have helped the John Williams Elementary School No. 5 in Rochester, New York, to create pathways to excellence and become a…

  5. Journey around Leadership

    ERIC Educational Resources Information Center

    Sinclair, Amanda

    2004-01-01

    Ideas about leadership in education, as in other areas of professional practice, increasingly borrow from management and business thinking. In this article I provide a commentary and critique of contemporary leadership in the form of a narrative of my own experience as an educator in a business school. My experience as a woman teacher of largely…

  6. The Journey to Recovery

    ERIC Educational Resources Information Center

    Reiman, Mary

    2012-01-01

    When 250 employees of Lincoln Public Schools (LPS) in Lincoln, Nebraska, left their workspaces in the administration building on Friday, May 25, 2011, they thought the only thing that was significant was that it was the last day of the 2010-2011 school year. However, on Monday evening, May 30, 2011, during a wind and rain storm, the 90,000 square…

  7. A Technology Enabled Journey

    ERIC Educational Resources Information Center

    Devine, Pamela Albert

    2012-01-01

    This article features Point Road School, a pre-K-4 school in New Jersey that enhances student learning by integrating new and emerging technologies into the curriculum. Point Road School's technology story began in 1996 with a grant for a classroom modem so students could email their university literacy buddies. The New Jersey school has moved…

  8. Geisinger's Retail Innovation Journey.

    PubMed

    Prince, Denise B; Graf, Thomas

    2015-01-01

    In 2003, Geisinger Health System formed a new group, Geisinger Ventures (GV), to accelerate the growth of new lines of business that were extensions of the core mission of the organization. Careworks, the convenient care clinic line of business, began in early 2006 as one of the early components of the GV portfolio. Over the past nine years, Geisinger has tested several retail and walk-in models, including in-store clinics, separate retail sites, and models colocated with primary care practices and emergency departments. Each site and model presents different benefits and challenges with respect to patient care, marketing, staffing, and clinical integration. With the implementation of healthcare reform and a decision to participate in Medicaid'managed care, Geisinger's strategic need for convenient care options has intensified, and new models, including e-visits and telemedicine specialty consultations, are being actively explored. Geisinger's view is that healthcare is rapidly changing, being affected by demographic shifts, diagnostic and treatment options, payment changes, and communication technologies. Healthcare delivery must flex to adjust to these and other trends, and retail clinics are part of that response. Careful examination of the critical elements necessary for optimal care (including wellness, prevention, and management of chronic disease and severe multimorbid disease) and then matching those elements to the optimal mode and site of care will lead to a streamlined healthcare system. The historical--and still most prevalent--methodology of traditional office, emergency department, and inpatient care options are not ideal for all patients' care needs in the twenty-first century. A thoughtful, deliberate extension of those options will be necessary. Rather than simply adding a static retail or virtual offering, medical professionals should develop a process to continually assess patients, technology, payment, and disease changes so that they are constantly adding exciting new options to the clinical delivery model. The ability to assess and respond to the changes that these varied inputs drive will be the most important element of success for the future. PMID:26495551

  9. An Edmonton Journey

    ERIC Educational Resources Information Center

    Archer, Jeff

    2005-01-01

    Educators from the United States flock to Edmonton, Alberta, a district in Canada where schools control 80% of the district's total budget. Education leaders from Chicago, Colorado, Hawaii, Los Angeles, Minnesota, Oakland, California, and the District of Columbia have all flocked to learn about Edmonton's experience with site-based management of…

  10. My Journey with Toxoplasmosis

    ERIC Educational Resources Information Center

    Winter-Messiers, Mary Ann

    2006-01-01

    The author describes her fears and struggles as she came to terms, as an American expatriate in France, with a medical diagnosis of Toxoplasmosis. This condition led to her birthing a son with Asperger's Syndrome. She tells of plunging herself into research to learn more about Toxoplasmosis, the number of things that could be seriously wrong with…

  11. The Transcultural Journey

    ERIC Educational Resources Information Center

    Slimbach, Richard

    2005-01-01

    Ready or not, a "transcultural" era is here. The dramatic expansion of airline travel and telecommunications technologies, tourism and student exchanges, immigration policies and trade agreements have served to connect vastly different peoples and places into increasingly complex relationships. Local, regional, and national economies are now…

  12. The Incredible Journey.

    ERIC Educational Resources Information Center

    Science Activities, 1995

    1995-01-01

    Presents a Project WET water education activity. Students simulate the movement of water within the water cycle by role-playing a water molecule's movements. Students learn the states of water as it moves through the water cycle. (LZ)

  13. A Simulated Journey

    ERIC Educational Resources Information Center

    Yoder, Lisa

    2006-01-01

    Students learn best when they interact with new information on a personal level. It is a challenge for teachers to tightly align student experiences with the standards assessed on high-stakes tests. To achieve this goal in social studies, the author has turned increasingly to simulations where students find such activities engaging, and their…

  14. The leadership journey.

    PubMed

    Schaeffer, Leonard D

    2002-10-01

    It isn't always easy to change leadership hats or to alter the way you assess a business problem. Under pressure, most executives fall back on the management style or approach that worked in the last crisis they faced. But old approaches rarely work in new and demanding situations. Just ask Leonard Schaeffer, chairman and CEO of WellPoint Health Networks, one of the country's largest and most successful managed-care companies. In this account, he describes how he consciously adopted three very different styles of leadership at critical points during his 30-year career, depending on the business challenges at hand. Schaeffer headed up the U.S. Health Care Finance Administration during the Carter years--and led the charge toward more efficient work practices at that agency. Then he transformed Blue Cross of California from a floundering bureaucracy losing close to $1 million each day into a strong public company, WellPoint. The dire circumstances at Blue Cross had dictated that Schaeffer initially be an autocratic leader, which he considers the managerial equivalent of being an emergency room surgeon--forced to do whatever it takes to save a patient's life. But as the company rebounded, the CEO shed that "any decision is better than no decision" style. He has become a participative, hands-off leader-setting strategies and goals from above but letting WellPoint's line managers and executives figure out how best to achieve those goals. Most recently, Schaeffer has turned into a reformer--a leader who works with one foot outside the company to spur changes in health care and society. There are pitfalls in switching leadership styles, Schaeffer admits, but this flexibility is necessary for realizing corporate- and personal-success. PMID:12389460

  15. Dillard's Culinary Journey

    ERIC Educational Resources Information Center

    Chew, Cassie M.

    2008-01-01

    A new institute at Dillard University promises to enliven scholarly research on the cultural and social history of the foods of the African diaspora. To be started next spring with $1-million from the late singer Ray Charles, the Institute for the Study of Culinary Cultures will oversee research, academic courses, public programs, and an annual…

  16. Old Journey, New Heights

    NASA Technical Reports Server (NTRS)

    DelFrate, John

    2005-01-01

    If you could see the road ahead, you might pass up a fantastic opportunity because you're blinded by the potential pitfalls. In my case, I was testing the project management waters at the NASA Dryden Flight Research Center after ten years of being a research engineer. I was an eager (but ignorant) rookie project manager (PM) and I was willing to engage in just about any project without knowing what it would entail. The assignment I accepted was to help NASA's Environment Research Aircraft and Sensor Technology (ERAST) Project, a partnership with a fledgling Uninhabited Aerial Vehicle (UAV) industry, to tackle stratospheric flight. I remember one of our industrial partners querying me about whether or not I understood what 1 was getting into. Like one of those bobble-head toys that have become quite popular, I nodded. But in reality, I didn't have a clue. His response was, "Hang on, it's going to be a wild ride." He was right. In retrospect, if I had clearly understood the ten years of pitfalls that were coming, I might not have "hung on." Now I can look back and say that I would not trade the experience for anything. The lows included the destruction of a number of UAVs on my watch. Later someone told me that we should not be surprised if we lost one UAV for every ten flights. We wrote many chapters in the book on what can go wrong with UAVs-and we are still writing. As you can imagine, each mishap was accompanied by an investigation. What an education!

  17. Thematic Journeys. Young Investigators

    ERIC Educational Resources Information Center

    Zingher, Gary

    2005-01-01

    Some children delight in pursuing information about a particular subject. They are excited about facts and theories, and want to know about the "how" as well as the "what" and the "who." They love the challenge of making connections and seeing the ways the pieces of any puzzle or mystery are linked together. On research projects, these young…

  18. A Principal's Journey

    ERIC Educational Resources Information Center

    Yergalonis, Edward

    2005-01-01

    In the interview process, every aspiring principal naively speaks of assuming the role of instructional leader. The candidate has read the right books, taken the right courses, and attended every possible workshop to prepare for the day when he or she would become captain of his or her own ship. However, it does not take long for principals to…

  19. Journey to the Reef

    ERIC Educational Resources Information Center

    Bryson, Linda

    2010-01-01

    Despite their experiences with a cartoon sponge, most elementary students know little about the diverse inhabitants of coral reefs. Therefore, with vivid photography and video, diverse coral reef inhabitants were brought to life for the author's fifth-grade students. Students shared their knowledge in language arts and even explored coral reefs in…

  20. Falling in love with minerals terra mineralia - a journey to the most beautiful minerals of the world

    NASA Astrophysics Data System (ADS)

    Anna, D.

    2013-12-01

    Is it possible to make people fall in love with minerals? Yes, it is. And it happens daily at terra mineralia, a permanent exhibition displaying a collection of 3500 rare and beautiful minerals, precious stones and meteorites in Freiberg/Saxony. The exhibits are part of one of the world's largest private collections of minerals and have been given to the TU Bergakademie Freiberg on permanent loan by Dr. Erika Pohl-Ströher. The exquisite pieces stem from sites on every continent, and as such, allow the visitor to virtually journey around the world to the world's most beautiful minerals - an amazing and unexpected experience. The specimen are so unique in quality and aesthetical appearance that scientists and private collectors from all over the world are overwhelmed by their display. However, the exhibition is less targeted towards the specialist or collector. Due to the close ties of the terra mineralia to its parent organization, the TU Bergakademie Freiberg, which is one of the leading universities dedicated to the geo-sciences, it has been primarily designed to attract young visitors, school children and students. It is the expressed goal of the University and Dr. Erika Pohl-Ströher to give young people the opportunity to discover the fascinating aspects natural sciences have to offer. Therefore, the efforts of the museums educational service focus on raising awareness and enticing the young 'scientists' to be. Why not continue a live of learning where the interest in natural sciences had been nurtured in first place - at the TU Bergakademie in Freiberg, for example with studies in the fields of mineralogy, geology or mining? And while you are at it, come back to terra mineralia as a student to help form and train the next generation of young talents. So, does it work? Yes, even if it is still too early to see the young enrolled in the University. What we already see, is a tremendous amount of positive feed back from the young, their parents and educators

  1. Single-Sex Classrooms

    ERIC Educational Resources Information Center

    Protheroe, Nancy

    2009-01-01

    Although single-sex education was once the norm in the U.S., the practice has largely been confined to private schools for more than a century. However, with the introduction of the final version of the U.S. Department of Education's so-called single-sex regulations in 2006, public schools were allowed greater flexibility to offer single-sex…

  2. Single Parent Adoption.

    ERIC Educational Resources Information Center

    Administration for Children, Youth, and Families (DHHS), Washington, DC.

    Presenting two views of the single-parent family, this pamphlet includes an article by two researchers (William Feigelman and Arnold R. Silverman) and a short statement by a single adoptive parent (Amanda Richards). The first paper summarizes earlier research on single-parent adoptions and discusses the results of a nationwide survey of 713…

  3. Single Molecule and Single Cell Epigenomics

    PubMed Central

    Hyun, Byung-Ryool; McElwee, John L.; Soloway, Paul D.

    2014-01-01

    Dynamically regulated changes in chromatin states are vital for normal development and can produce disease when they go awry. Accordingly, much effort has been devoted to characterizing these states under normal and pathological conditions. Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is the most widely used method to characterize where in the genome transcription factors, modified histones, modified nucleotides and chromatin binding proteins are found; bisulfite sequencing (BS-seq) and its variants are commonly used to characterize the locations of DNA modifications. Though very powerful, these methods are not without limitations. Notably, they are best at characterizing one chromatin feature at a time, yet chromatin features arise and function in combination. Investigators commonly superimpose separate ChIP-seq or BS-seq datasets, and then infer where chromatin features are found together. While these inferences might be correct, they can be misleading when the chromatin source has distinct cell types, or when a given cell type exhibits any cell to cell variation in chromatin state. These ambiguities can be eliminated by robust methods that directly characterize the existence and genomic locations of combinations of chromatin features in very small inputs of cells or ideally, single cells. Here we review single molecule epigenomic methods under development to overcome these limitations, the technical challenges associated with single molecule methods and their potential application to single cells. PMID:25204781

  4. Single Mothers "Do" Family

    ERIC Educational Resources Information Center

    Nelson, Margaret K.

    2006-01-01

    This paper explores how single mothers both incorporate others into family life (e.g., when they ask others to care for their children) and simultaneously "do families" in a manner that holds out a vision of a "traditional" family structure. Drawing on research with White, rural single mothers, the author explores the manner in which these women…

  5. Single Parent Adoptive Homes.

    ERIC Educational Resources Information Center

    Shireman, Joan F.

    1996-01-01

    Reviews research and reports on a longitudinal study of 15 single-parent adoptive homes over a 14-year period that demonstrated that these homes have the capacity to be successful adoptive placements. Identifies unique characteristics of single-parent adoptive homes, and notes the need for additional research to identify children for whom these…

  6. Understanding Single Adulthood.

    ERIC Educational Resources Information Center

    Stein, Peter J.

    The life styles and life chances of the unmarried include elements of choices. Singles may be grouped and characterized according to whether their status may be considered stable or temporary. A life cycle, or continuum model of singlehood is reviewed, including its different factors, or phases. A new model for singles is proposed--a life spiral…

  7. Moving Single Atoms

    NASA Astrophysics Data System (ADS)

    Stuart, Dustin

    2016-05-01

    Single neutral atoms are promising candidates for qubits, the fundamental unit of quantum information. We have built a set of optical tweezers for trapping and moving single Rubidium atoms. The tweezers are based on a far off-resonant dipole trapping laser focussed to a 1 μm spot with a single aspheric lens. We use a digital micromirror device (DMD) to generate dynamic holograms of the desired arrangement of traps. The DMD has a frame rate of 20 kHz which, when combined with fast algorithms, allows for rapid reconfiguration of the traps. We demonstrate trapping of up to 20 atoms in arbitrary arrangements, and the transport of a single-atom over a distance of 14 μm with continuous laser cooling, and 5 μm without. In the meantime, we are developing high-finesse fibre-tip cavities, which we plan to use to couple pairs of single atoms to form a quantum network.

  8. Single nanoparticle plasmonic sensors.

    PubMed

    Sriram, Manish; Zong, Kelly; Vivekchand, S R C; Gooding, J Justin

    2015-01-01

    The adoption of plasmonic nanomaterials in optical sensors, coupled with the advances in detection techniques, has opened the way for biosensing with single plasmonic particles. Single nanoparticle sensors offer the potential to analyse biochemical interactions at a single-molecule level, thereby allowing us to capture even more information than ensemble measurements. We introduce the concepts behind single nanoparticle sensing and how the localised surface plasmon resonances of these nanoparticles are dependent upon their materials, shape and size. Then we outline the different synthetic approaches, like citrate reduction, seed-mediated and seedless growth, that enable the synthesis of gold and silver nanospheres, nanorods, nanostars, nanoprisms and other nanostructures with tunable sizes. Further, we go into the aspects related to purification and functionalisation of nanoparticles, prior to the fabrication of sensing surfaces. Finally, the recent developments in single nanoparticle detection, spectroscopy and sensing applications are discussed. PMID:26473866

  9. Single Nanoparticle Plasmonic Sensors

    PubMed Central

    Sriram, Manish; Zong, Kelly; Vivekchand, S. R. C.; Gooding, J. Justin

    2015-01-01

    The adoption of plasmonic nanomaterials in optical sensors, coupled with the advances in detection techniques, has opened the way for biosensing with single plasmonic particles. Single nanoparticle sensors offer the potential to analyse biochemical interactions at a single-molecule level, thereby allowing us to capture even more information than ensemble measurements. We introduce the concepts behind single nanoparticle sensing and how the localised surface plasmon resonances of these nanoparticles are dependent upon their materials, shape and size. Then we outline the different synthetic approaches, like citrate reduction, seed-mediated and seedless growth, that enable the synthesis of gold and silver nanospheres, nanorods, nanostars, nanoprisms and other nanostructures with tunable sizes. Further, we go into the aspects related to purification and functionalisation of nanoparticles, prior to the fabrication of sensing surfaces. Finally, the recent developments in single nanoparticle detection, spectroscopy and sensing applications are discussed. PMID:26473866

  10. Single-ventricle physiology.

    PubMed

    Schwartz, Steven M; Dent, Catherine L; Musa, Ndidi L; Nelson, David P

    2003-07-01

    The patient with single-ventricle physiology presents a significant challenge to the intensive care team at all stages of management. An integrated approach that applies a working knowledge of cardiac anatomy, cardiopulmonary physiology, and the basic principles of intensive care is essential to guide management for each individual patient. This management requires cooperative and constructive involvement of surgeons, cardiologists, and intensivists, as well as a nursing and respiratory care team experienced in the management of single-ventricle patients. The outcome of each stage of palliation for single-ventricle lesions should continue to improve as new ideas are developed and as older ideas are subjected to rigorous scientific analyses. PMID:12848312

  11. Single Electron Tunneling

    SciTech Connect

    Ruggiero, Steven T.

    2005-07-25

    Financial support for this project has led to advances in the science of single-electron phenomena. Our group reported the first observation of the so-called ''Coulomb Staircase'', which was produced by tunneling into ultra-small metal particles. This work showed well-defined tunneling voltage steps of width e/C and height e/RC, demonstrating tunneling quantized on the single-electron level. This work was published in a now well-cited Physical Review Letter. Single-electron physics is now a major sub-field of condensed-matter physics, and fundamental work in the area continues to be conducted by tunneling in ultra-small metal particles. In addition, there are now single-electron transistors that add a controlling gate to modulate the charge on ultra-small photolithographically defined capacitive elements. Single-electron transistors are now at the heart of at least one experimental quantum-computer element, and single-electron transistor pumps may soon be used to define fundamental quantities such as the farad (capacitance) and the ampere (current). Novel computer technology based on single-electron quantum dots is also being developed. In related work, our group played the leading role in the explanation of experimental results observed during the initial phases of tunneling experiments with the high-temperature superconductors. When so-called ''multiple-gap'' tunneling was reported, the phenomenon was correctly identified by our group as single-electron tunneling in small grains in the material. The main focus throughout this project has been to explore single electron phenomena both in traditional tunneling formats of the type metal/insulator/particles/insulator/metal and using scanning tunneling microscopy to probe few-particle systems. This has been done under varying conditions of temperature, applied magnetic field, and with different materials systems. These have included metals, semi-metals, and superconductors. Amongst a number of results, we have

  12. Single Beam Holography.

    ERIC Educational Resources Information Center

    Chen, Hsuan; Ruterbusch, Paul H.

    1979-01-01

    Discusses how holography can be used as part of undergraduate physics laboratories. The authors propose a single beam technique of holography, which will reduce the recording scheme as well as relax the isolation requirements. (HM)

  13. SINGLE CELL GENOME SEQUENCING

    PubMed Central

    Yilmaz, Suzan; Singh, Anup K.

    2011-01-01

    Whole genome amplification and next-generation sequencing of single cells has become a powerful approach for studying uncultivated microorganisms that represent 90–99 % of all environmental microbes. Single cell sequencing enables not only the identification of microbes but also linking of functions to species, a feat not achievable by metagenomic techniques. Moreover, it allows the analysis of low abundance species that may be missed in community-based analyses. It has also proved very useful in complementing metagenomics in the assembly and binning of single genomes. With the advent of drastically cheaper and higher throughput sequencing technologies, it is expected that single cell sequencing will become a standard tool in studying the genome and transcriptome of microbial communities. PMID:22154471

  14. Is there a difference between stripy journeys and stripy ladybirds? The N400 response to semantic and world-knowledge violations during sentence processing.

    PubMed

    Dudschig, Carolin; Maienborn, Claudia; Kaup, Barbara

    2016-03-01

    The distinction between linguistic and non-linguistic knowledge is particularly relevant because it is related to the principle of compositionality during sentence comprehension. Hagoort, Hald, Bastiaansen, and Petersson (2004) challenged the distinction between linguistic and non-linguistic knowledge. Here, we investigate how linguistic and non-linguistic violations are processed in a setting adapted from Hagoort et al., whilst in contrast to Hagoort, keeping the critical word identical. In line with the findings by Hagoort et al., our results showed largest N400 amplitudes for semantic violations ('Journeys are stripy'), followed by non-linguistic world-knowledge violations ('Ladybirds are stripy') and contingent sentences ('Trousers are stripy'), and finally by correct sentences ('Zebras are stripy'). Traditional fractional area and relative criterion measures of peak and onset latencies showed no effect of violation type. Interestingly, the semantic violation condition crossed a fixed criterion earlier than the word-knowledge violation condition. In conclusion, our data suggests that the question regarding the distinction between linguistic- and non-linguistic knowledge in terms of language integration remains open. Implications for future studies addressing the difference between linguistic and non-linguistic knowledge are discussed. PMID:26812249

  15. Do Seabirds Differ from Other Migrants in Their Travel Arrangements? On Route Strategies of Cory’s Shearwater during Its Trans-Equatorial Journey

    PubMed Central

    Dias, Maria P.; Granadeiro, José P.; Catry, Paulo

    2012-01-01

    Long-distance migrants have developed diverse strategies to deal with the challenges imposed by their annual journeys. These are relatively well studied in some avian groups, such as passerines, shorebirds and raptors. In contrast, few studies have addressed the migratory behaviour of pelagic birds in the light of current theories of optimal migration. Using a dataset of 100 complete migratory tracks gathered along four years, we performed a detailed study on the migratory strategy of a pelagic trans-equatorial migrant, the Cory’s shearwater Calonectris diomedea. We analysed daily routines, stopover ecology and travel speed, as well as the influence of the moon on several behavioural patterns. Cory’s shearwaters adopted a “fly-and-forage” strategy when migrating, similarly to what has been observed in some raptors. However, by flying by dynamic soaring, shearwaters attained high overall migration speeds, and were able to travel thousands of kilometres without making major stopovers and, apparently, without a noticeable pre-migratory fattening period. Other major findings of this study include the ability to adapt daily schedules when crossing major ecological barriers, and the constant adjustment of migration speed implying higher rates of travel in the pre-breeding movement, with a final sprint to the nesting colony. The present study also highlights a preference of Cory’s shearwaters for starting travel at twilight and documents a strong relationship between their migratory activity and the moon phase. PMID:23145168

  16. IL-15–PI3K–AKT–mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells

    PubMed Central

    Ali, Alaa Kassim; Nandagopal, Neethi; Lee, Seung-Hwan

    2015-01-01

    Among numerous cytokines modulating natural killer (NK) cell function, interleukin 15 (IL-15) exerts a broad range of effect from development and homeostasis, to activation of mature NK cells during infection. Its significance is further highlighted by clinical trials in which IL-15 is being used to boost the proliferation and anti-tumor response of NK cells. Among the signal transduction pathways triggered by the engagement of IL-15 receptor with its ligand, the PI3K–AKT–mTOR pathway seems to be critical for the IL-15-mediated activation of NK cells, therefore being responsible for efficient anti-viral and anti-tumor responses. This review provides an overview of the role of IL-15 at multiple stages of NK cell life journey. Understanding the pathway by which IL-15 conveys critical signals for the generation of NK cells with efficient effector functions, in combination with established protocols for NK cell expansion ex vivo, will undoubtedly open new avenues for therapeutic applications for immunomodulation against infections and cancers. PMID:26257729

  17. Single spin magnetic resonance

    NASA Astrophysics Data System (ADS)

    Wrachtrup, Jörg; Finkler, Amit

    2016-08-01

    Different approaches have improved the sensitivity of either electron or nuclear magnetic resonance to the single spin level. For optical detection it has essentially become routine to observe a single electron spin or nuclear spin. Typically, the systems in use are carefully designed to allow for single spin detection and manipulation, and of those systems, diamond spin defects rank very high, being so robust that they can be addressed, read out and coherently controlled even under ambient conditions and in a versatile set of nanostructures. This renders them as a new type of sensor, which has been shown to detect single electron and nuclear spins among other quantities like force, pressure and temperature. Adapting pulse sequences from classic NMR and EPR, and combined with high resolution optical microscopy, proximity to the target sample and nanoscale size, the diamond sensors have the potential to constitute a new class of magnetic resonance detectors with single spin sensitivity. As diamond sensors can be operated under ambient conditions, they offer potential application across a multitude of disciplines. Here we review the different existing techniques for magnetic resonance, with a focus on diamond defect spin sensors, showing their potential as versatile sensors for ultra-sensitive magnetic resonance with nanoscale spatial resolution.

  18. Single spin magnetic resonance.

    PubMed

    Wrachtrup, Jörg; Finkler, Amit

    2016-08-01

    Different approaches have improved the sensitivity of either electron or nuclear magnetic resonance to the single spin level. For optical detection it has essentially become routine to observe a single electron spin or nuclear spin. Typically, the systems in use are carefully designed to allow for single spin detection and manipulation, and of those systems, diamond spin defects rank very high, being so robust that they can be addressed, read out and coherently controlled even under ambient conditions and in a versatile set of nanostructures. This renders them as a new type of sensor, which has been shown to detect single electron and nuclear spins among other quantities like force, pressure and temperature. Adapting pulse sequences from classic NMR and EPR, and combined with high resolution optical microscopy, proximity to the target sample and nanoscale size, the diamond sensors have the potential to constitute a new class of magnetic resonance detectors with single spin sensitivity. As diamond sensors can be operated under ambient conditions, they offer potential application across a multitude of disciplines. Here we review the different existing techniques for magnetic resonance, with a focus on diamond defect spin sensors, showing their potential as versatile sensors for ultra-sensitive magnetic resonance with nanoscale spatial resolution. PMID:27378060

  19. Single-plasmon interferences.

    PubMed

    Dheur, Marie-Christine; Devaux, Eloïse; Ebbesen, Thomas W; Baron, Alexandre; Rodier, Jean-Claude; Hugonin, Jean-Paul; Lalanne, Philippe; Greffet, Jean-Jacques; Messin, Gaétan; Marquier, François

    2016-03-01

    Surface plasmon polaritons are electromagnetic waves coupled to collective electron oscillations propagating along metal-dielectric interfaces, exhibiting a bosonic character. Recent experiments involving surface plasmons guided by wires or stripes allowed the reproduction of quantum optics effects, such as antibunching with a single surface plasmon state, coalescence with a two-plasmon state, conservation of squeezing, or entanglement through plasmonic channels. We report the first direct demonstration of the wave-particle duality for a single surface plasmon freely propagating along a planar metal-air interface. We develop a platform that enables two complementary experiments, one revealing the particle behavior of the single-plasmon state through antibunching, and the other one where the interferences prove its wave nature. This result opens up new ways to exploit quantum conversion effects between different bosonic species as shown here with photons and polaritons. PMID:26998521

  20. Single event mass spectrometry

    DOEpatents

    Conzemius, Robert J.

    1990-01-16

    A means and method for single event time of flight mass spectrometry for analysis of specimen materials. The method of the invention includes pulsing an ion source imposing at least one pulsed ion onto the specimen to produce a corresponding emission of at least one electrically charged particle. The emitted particle is then dissociated into a charged ion component and an uncharged neutral component. The ion and neutral components are then detected. The time of flight of the components are recorded and can be used to analyze the predecessor of the components, and therefore the specimen material. When more than one ion particle is emitted from the specimen per single ion impact, the single event time of flight mass spectrometer described here furnis This invention was made with Government support under Contract No. W-7405-ENG82 awarded by the Department of Energy. The Government has certain rights in the invention.

  1. Single-Molecule Bioelectronics

    PubMed Central

    Rosenstein, Jacob K.; Lemay, Serge G.; Shepard, Kenneth L.

    2014-01-01

    Experimental techniques which interface single biomolecules directly with microelectronic systems are increasingly being used in a wide range of powerful applications, from fundamental studies of biomolecules to ultra-sensitive assays. Here we review several technologies which can perform electronic measurements of single molecules in solution: ion channels, nanopore sensors, carbon nanotube field-effect transistors, electron tunneling gaps, and redox cycling. We discuss the shared features among these techniques that enable them to resolve individual molecules, and discuss their limitations. Recordings from each of these methods all rely on similar electronic instrumentation, and we discuss the relevant circuit implementations and potential for scaling these single-molecule bioelectronic interfaces to high-throughput arrayed sensing platforms. PMID:25529538

  2. Single-plasmon interferences

    PubMed Central

    Dheur, Marie-Christine; Devaux, Eloïse; Ebbesen, Thomas W.; Baron, Alexandre; Rodier, Jean-Claude; Hugonin, Jean-Paul; Lalanne, Philippe; Greffet, Jean-Jacques; Messin, Gaétan; Marquier, François

    2016-01-01

    Surface plasmon polaritons are electromagnetic waves coupled to collective electron oscillations propagating along metal-dielectric interfaces, exhibiting a bosonic character. Recent experiments involving surface plasmons guided by wires or stripes allowed the reproduction of quantum optics effects, such as antibunching with a single surface plasmon state, coalescence with a two-plasmon state, conservation of squeezing, or entanglement through plasmonic channels. We report the first direct demonstration of the wave-particle duality for a single surface plasmon freely propagating along a planar metal-air interface. We develop a platform that enables two complementary experiments, one revealing the particle behavior of the single-plasmon state through antibunching, and the other one where the interferences prove its wave nature. This result opens up new ways to exploit quantum conversion effects between different bosonic species as shown here with photons and polaritons. PMID:26998521

  3. Single-molecule bioelectronics.

    PubMed

    Rosenstein, Jacob K; Lemay, Serge G; Shepard, Kenneth L

    2015-01-01

    Experimental techniques that interface single biomolecules directly with microelectronic systems are increasingly being used in a wide range of powerful applications, from fundamental studies of biomolecules to ultra-sensitive assays. In this study, we review several technologies that can perform electronic measurements of single molecules in solution: ion channels, nanopore sensors, carbon nanotube field-effect transistors, electron tunneling gaps, and redox cycling. We discuss the shared features among these techniques that enable them to resolve individual molecules, and discuss their limitations. Recordings from each of these methods all rely on similar electronic instrumentation, and we discuss the relevant circuit implementations and potential for scaling these single-molecule bioelectronic interfaces to high-throughput arrayed sensing platforms. PMID:25529538

  4. Single Cell Oncogenesis

    NASA Astrophysics Data System (ADS)

    Lu, Xin

    It is believed that cancer originates from a single cell that has gone through generations of evolution of genetic and epigenetic changes that associate with the hallmarks of cancer. In some cancers such as various types of leukemia, cancer is clonal. Yet in other cancers like glioblastoma (GBM), there is tremendous tumor heterogeneity that is likely to be caused by simultaneous evolution of multiple subclones within the same tissue. It is obvious that understanding how a single cell develops into a clonal tumor upon genetic alterations, at molecular and cellular levels, holds the key to the real appreciation of tumor etiology and ultimate solution for therapeutics. Surprisingly very little is known about the process of spontaneous tumorigenesis from single cells in human or vertebrate animal models. The main reason is the lack of technology to track the natural process of single cell changes from a homeostatic state to a progressively cancerous state. Recently, we developed a patented compound, photoactivatable (''caged'') tamoxifen analogue 4-OHC and associated technique called optochemogenetic switch (OCG switch), which we believe opens the opportunity to address this urgent biological as well as clinical question about cancer. We propose to combine OCG switch with genetically engineered mouse models of head and neck squamous cell carcinoma and high grade astrocytoma (including GBM) to study how single cells, when transformed through acute loss of tumor suppressor genes PTEN and TP53 and gain of oncogenic KRAS, can develop into tumor colonies with cellular and molecular heterogeneity in these tissues. The abstract is for my invited talk in session ``Beyond Darwin: Evolution in Single Cells'' 3/18/2016 11:15 AM.

  5. TRANSVERSITY SINGLE SPIN ASYMMETRIES.

    SciTech Connect

    BOER,D.

    2001-04-27

    The theoretical aspects of two leading twist transversity single spin asymmetries, one arising from the Collins effect and one from the interference fragmentation functions, are reviewed. Issues of factorization, evolution and Sudakov factors for the relevant observables are discussed. These theoretical considerations pinpoint the most realistic scenarios towards measurements of transversity.

  6. Contemporary Single Mothers.

    ERIC Educational Resources Information Center

    Eiduson, Bernice T.

    Fifty Caucasian, never-married single mothers aged 18-30, who had opted to keep their babies, were studied longitudinally from the last trimester of pregnancy through the first three years of their children's lives in order to learn the extent to which they had reinterpreted traditional roles and responsibilities and had restructured their lives.…

  7. Single Mother's Resource Handbook.

    ERIC Educational Resources Information Center

    Ferando, Annette; Newbert, David

    Funded under the Women's Educational Equity Act, the Assertiveness Training Program for Single Mothers was offered to mothers with children enrolled in the Omaha Head Start and Parent-Child Center Programs. The 16-week long program, providing a total of 40 hours of training, covered a wide range of topics in addition to the initial workshops on…

  8. Single Fathers Rearing Children.

    ERIC Educational Resources Information Center

    Greif, Geoffrey L.

    1985-01-01

    Describes single fathers rearing children alone following divorce (N=1,136). Findings revealed four primary reasons for the divorce and four broad situations in which the fathers obtained custody. These latter situations often are affected by the mother's desire to relinquish custody. (NRB)

  9. From single molecule to single tubules

    NASA Astrophysics Data System (ADS)

    Guo, Chin-Lin

    2012-02-01

    Biological systems often make decisions upon conformational changes and assembly of single molecules. In vivo, epithelial cells (such as the mammary gland cells) can respond to extracellular matrix (ECM) molecules, type I collagen (COL), and switch their morphology from a lobular lumen (100-200 micron) to a tubular lumen (1mm-1cm). However, how cells make such a morphogenetic decision through interactions with each other and with COL is unclear. Using a temporal control of cell-ECM interaction, we find that epithelial cells, in response to a fine-tuned percentage of type I collagen (COL) in ECM, develop various linear patterns. Remarkably, these patterns allow cells to self-assemble into a tubule of length ˜ 1cm and diameter ˜ 400 micron in the liquid phase (i.e., scaffold-free conditions). In contrast with conventional thought, the linear patterns arise through bi-directional transmission of traction force, but not through diffusible biochemical factors secreted by cells. In turn, the transmission of force evokes a long-range (˜ 600 micron) intercellular mechanical interaction. A feedback effect is encountered when the mechanical interaction modifies cell positioning and COL alignment. Micro-patterning experiments further reveal that such a feedback is a novel cell-number-dependent, rich-get-richer process, which allows cells to integrate mechanical interactions into long-range (> 1mm) linear coordination. Our results suggest a mechanism cells can use to form and coordinate long-range tubular patterns, independent of those controlled by diffusible biochemical factors, and provide a new strategy to engineer/regenerate epithelial organs using scaffold-free self-assembly methods.

  10. Towards single molecule switches.

    PubMed

    Zhang, Jia Lin; Zhong, Jian Qiang; Lin, Jia Dan; Hu, Wen Ping; Wu, Kai; Xu, Guo Qin; Wee, Andrew T S; Chen, Wei

    2015-05-21

    The concept of using single molecules as key building blocks for logic gates, diodes and transistors to perform basic functions of digital electronic devices at the molecular scale has been explored over the past decades. However, in addition to mimicking the basic functions of current silicon devices, molecules often possess unique properties that have no parallel in conventional materials and promise new hybrid devices with novel functions that cannot be achieved with equivalent solid-state devices. The most appealing example is the molecular switch. Over the past decade, molecular switches on surfaces have been intensely investigated. A variety of external stimuli such as light, electric field, temperature, tunneling electrons and even chemical stimulus have been used to activate these molecular switches between bistable or even multiple states by manipulating molecular conformations, dipole orientations, spin states, charge states and even chemical bond formation. The switching event can occur either on surfaces or in break junctions. The aim of this review is to highlight recent advances in molecular switches triggered by various external stimuli, as investigated by low-temperature scanning tunneling microscopy (LT-STM) and the break junction technique. We begin by presenting the molecular switches triggered by various external stimuli that do not provide single molecule selectivity, referred to as non-selective switching. Special focus is then given to selective single molecule switching realized using the LT-STM tip on surfaces. Single molecule switches operated by different mechanisms are reviewed and discussed. Finally, molecular switches embedded in self-assembled monolayers (SAMs) and single molecule junctions are addressed. PMID:25757483

  11. 75 FR 9247 - Single Family Mortgage Insurance Premium, Single Family

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-01

    ... URBAN DEVELOPMENT Single Family Mortgage Insurance Premium, Single Family AGENCY: Office of the Chief... the Single Family Premium Collection Subsystem-Upfront (SFPCS-U) to remit the upfront premium to... manage and process upfront single family mortgage insurance premium collections and corrections to...

  12. Modeling the Patient Journey from Injury to Community Reintegration for Persons with Acute Traumatic Spinal Cord Injury in a Canadian Centre

    PubMed Central

    Santos, Argelio; Gurling, James; Dvorak, Marcel F.; Noonan, Vanessa K.; Fehlings, Michael G.; Burns, Anthony S.; Lewis, Rachel; Soril, Lesley; Fallah, Nader; Street, John T.; Bélanger, Lise; Townson, Andrea; Liang, Liping; Atkins, Derek

    2013-01-01

    Background A patient’s journey through the health care system is influenced by clinical and system processes across the continuum of care. Methods To inform optimized access to care and patient flow for individuals with traumatic spinal cord injury (tSCI), we developed a simulation model that can examine the full impact of therapeutic or systems interventions across the care continuum for patients with traumatic spinal cord injuries. The objective of this paper is to describe the detailed development of this simulation model for a major trauma and a rehabilitation centre in British Columbia (BC), Canada, as part of the Access to Care and Timing (ACT) project and is referred to as the BC ACT Model V1.0. Findings To demonstrate the utility of the simulation model in clinical and administrative decision-making we present three typical scenarios that illustrate how an investigator can track the indirect impact(s) of medical and administrative interventions, both upstream and downstream along the continuum of care. For example, the model was used to estimate the theoretical impact of a practice that reduced the incidence of pressure ulcers by 70%. This led to a decrease in acute and rehabilitation length of stay of 4 and 2 days, respectively and a decrease in bed utilization of 9% and 3% in acute and rehabilitation. Conclusion The scenario analysis using the BC ACT Model V1.0 demonstrates the flexibility and value of the simulation model as a decision-making tool by providing estimates of the effects of different interventions and allowing them to be objectively compared. Future work will involve developing a generalizable national Canadian ACT Model to examine differences in care delivery and identify the ideal attributes of SCI care delivery. PMID:24023623

  13. A Community College Instructor's Reflective Journey Toward Developing Pedagogical Content Knowledge for Nature of Science in a Non-majors Undergraduate Biology Course

    NASA Astrophysics Data System (ADS)

    Krajewski, Sarah J.; Schwartz, Renee

    2014-08-01

    Research supports an explicit-reflective approach to teaching about nature of science (NOS), but little is reported on teachers' journeys as they attempt to integrate NOS into everyday lessons. This participatory action research paper reports the challenges and successes encountered by an in-service teacher, Sarah, implementing NOS for the first time throughout four units of a community college biology course (genetics, molecular biology, evolution, and ecology). Through the action research cycles of planning, implementing, and reflecting, Sarah identified areas of challenge and success. This paper reports emergent themes that assisted her in successfully embedding NOS within the science content. Data include weekly lesson plans and pre/post reflective journaling before and after each lesson of this lecture/lab combination class that met twice a week. This course was taught back to back semesters, and this study is based on the results of a year-long process. Developing pedagogical content knowledge (PCK) for NOS involves coming to understand the overlaps and connections between NOS, other science subject matter, pedagogical strategies, and student learning. Sarah found that through action research she was able to grow and assimilate her understanding of NOS within the biology content she was teaching. A shift in orientation toward teaching products of science to teaching science processes was a necessary shift for NOS pedagogical success. This process enabled Sarah's development of PCK for NOS. As a practical example of putting research-based instructional recommendations into practice, this study may be very useful for other teachers who are learning to teach NOS.

  14. Single nanowire photovoltaics.

    PubMed

    Tian, Bozhi; Kempa, Thomas J; Lieber, Charles M

    2009-01-01

    This tutorial review focuses on recent work addressing the properties and potential of semiconductor nanowires as building blocks for photovoltaic devices based on investigations at the single nanowire level. Two central nanowire motifs involving p-i-n dopant modulation in axial and coaxial geometries serve as platforms for fundamental studies. Research illustrating the synthesis of these structural motifs will be reviewed first, followed by an examination of recent studies of single axial and coaxial p-i-n silicon nanowire solar cells. Finally, challenges and opportunities for improving efficiency enabled by controlled synthesis of more complex nanowire structures will be discussed, as will their potential applications as power sources for emerging nanoelectronic devices. PMID:19088961

  15. Single Crystal Membranes

    NASA Technical Reports Server (NTRS)

    Stormont, R. W.; Morrison, A.

    1974-01-01

    Single crystal a- and c-axis tubes and ribbons of sodium beta-alumina and sodium magnesium beta-alumina were grown from sodium oxide rich melts. Additional experiments grew ribbon crystals containing sodium magnesium beta, beta double prime, beta triple prime, and beta quadruple prime. A high pressure crystal growth chamber, sodium oxide rich melts, and iridium for all surfaces in contact with the melt were combined with the edge-defined, film-fed growth technique to grow the single crystal beta-alumina tubes and ribbons. The crystals were characterized using metallographic and X-ray diffraction techniques, and wet chemical analysis was used to determine the sodium, magnesium, and aluminum content of the grown crystals.

  16. Single frequency multitransmitter telemetry

    NASA Technical Reports Server (NTRS)

    Carreno, Victor A. (Inventor)

    1986-01-01

    The invention relates to a single frequency multitransmitter telemetry system that will deliver a substantial amount of data at low cost. The invention consists essentially of a plurality of sensor transmitter units at different locations, with individual signal conditioning and logic, which send sampled data signals to a single receiver. The transmitters operate independently on the same frequency in a frequency shift keying modulation system and are not synchronized to the receiver. The problem of reception of data from more than one transmitter simultaneously is solved by discarding the data - when there is overlap of data from two or more transmitters, the data is discarded and when there is no overlap the data is retained. The invention utilizes a unique overlap detection technique to determine if data should be retained or discarded. When data is received from a transmitter, it goes into a shift register.

  17. Single cell optical transfection.

    PubMed

    Stevenson, David J; Gunn-Moore, Frank J; Campbell, Paul; Dholakia, Kishan

    2010-06-01

    The plasma membrane of a eukaryotic cell is impermeable to most hydrophilic substances, yet the insertion of these materials into cells is an extremely important and universal requirement for the cell biologist. To address this need, many transfection techniques have been developed including viral, lipoplex, polyplex, capillary microinjection, gene gun and electroporation. The current discussion explores a procedure called optical injection, where a laser field transiently increases the membrane permeability to allow species to be internalized. If the internalized substance is a nucleic acid, such as DNA, RNA or small interfering RNA (siRNA), then the process is called optical transfection. This contactless, aseptic, single cell transfection method provides a key nanosurgical tool to the microscopist-the intracellular delivery of reagents and single nanoscopic objects. The experimental possibilities enabled by this technology are only beginning to be realized. A review of optical transfection is presented, along with a forecast of future applications of this rapidly developing and exciting technology. PMID:20064901

  18. Single mode thermal emission.

    PubMed

    Fohrmann, Lena Simone; Petrov, Alexander Yu; Lang, Slawa; Jalas, Dirk; Krauss, Thomas F; Eich, Manfred

    2015-10-19

    We report on the properties of a thermal emitter which radiates into a single mode waveguide. We show that the maximal power of thermal radiation into a propagating single mode is limited only by the temperature of the thermal emitter and does not depend on other parameters of the waveguide. Furthermore, we show that the power of the thermal emitter cannot be increased by resonant coupling. For a given temperature, the enhancement of the total emitted power is only possible if the number of excited modes is increased. Either a narrowband or a broadband thermal excitation of the mode is possible, depending on the properties of the emitter. We finally discuss an example system, namely a thermal source for silicon photonics. PMID:26480429

  19. The journey from the old to the new AMH assay: how to avoid getting lost in the values.

    PubMed

    Nelson, S M; La Marca, A

    2011-10-01

    Anti-Müllerian hormone (AMH) is set to dominate reproductive endocrinology because of its unique relationship with the ovarian reserve. To date half of the published articles have used the Diagnostic Systems Lab (DSL) assay and the other half the Immunotech (IOT) assay. Unfortunately, these assays utilize two different primary antibodies against AMH and different standards, and consequently the crude values reported can differ substantially, with the IOT assay giving values for AMH that are higher than those obtained with the DSL assay. With the recent consolidation of these two companies by Beckman Coulter, and their sole ownership of the patent to measure mammalian AMH, there is finally a single commercially available assay - the AMH Gen II assay, which will fully replace the DSL and IOT assays. The aim of this article is to briefly focus on the different assays for AMH evaluation in order to give readers hopefully helpful suggestions for a correct interpretation of the AMH measurement. A brief overview on the development and performance characteristics of the new assay, how it relates to previous values and previously developed nomograms and where the future lies for AMH is also provided. PMID:21872528

  20. Biomarkers for Psychiatry: The Journey from Fantasy to Fact, a Report of the 2013 CINP Think Tank

    PubMed Central

    Millan, Mark J.; Bahn, Sabine; Bertolino, Alessandro; Turck, Christoph W.; Kapur, Shitij; Möller, Hans-Jürgen; Dean, Brian

    2015-01-01

    Background: A think tank sponsored by the Collegium Internationale Neuropsychopharmacologium (CINP) debated the status and prospects of biological markers for psychiatric disorders, focusing on schizophrenia and major depressive disorder. Methods: Discussions covered markers defining and predicting specific disorders or domains of dysfunction, as well as predicting and monitoring medication efficacy. Deliberations included clinically useful and viable biomarkers, why suitable markers are not available, and the need for tightly-controlled sample collection. Results: Different types of biomarkers, appropriate sensitivity, specificity, and broad-based exploitability were discussed. Whilst a number of candidates are in the discovery phases, all will require replication in larger, real-life cohorts. Clinical cost-effectiveness also needs to be established. Conclusions: Since a single measure is unlikely to suffice, multi-modal strategies look more promising, although they bring greater technical and implementation complexities. Identifying reproducible, robust biomarkers will probably require pre-competitive consortia to provide the resources needed to identify, validate, and develop the relevant clinical tests. PMID:25899066