Science.gov

Sample records for single transient test

  1. Columbia University flow instability experimental program: Volume 6. Single annulus tests, transient test program

    SciTech Connect

    Dougherty, T.; Maciuca, C.; McAssey, E.V. Jr.; Reddy, D.G.; Yang, B.W.

    1992-09-01

    The coolant in the Savannah River Site (SRS) production nuclear reactor assemblies is circulated as a subcooled liquid under normal operating conditions. This coolant is evenly distributed throughout multiple annular flow channels with a uniform pressure profile across each coolant flow channel. During the postulated Loss of Coolant Accident (LOCA), which is initiated by a hypothetical guillotine pipe break, the coolant flow through the reactor assemblies is significantly reduced. The flow reduction and accompanying power reduction (after shutdown is initiated) occur in the first 1 to 2 seconds of the LOCA. This portion of the LOCA is referred to as the Flow Instability phase. This report presents the experimental results for the transient portion of the single annulus test program. The test program was designed to investigate the onset of flow instability in an annular geometry similar to the MARK 22 reactor. The test program involved testing of both a ribless heater and a ribbed heater under steady state as well as transient conditions. The ribbed heater testing is currently underway and will be reported separately. The steady state portion of this test program with ribless heater was completed and reported in report No. CU-HTRF-T3A. The present report presents transient test results obtained from a ribless, uniform annulus test section. A total of thirty five transients were conducted with six cases in which flow excursion occurred. No unstable conditions resulted for tests in which the steady state Q{sub ratio} OFI limit was not exceeded.

  2. Analysis of the single-blow transient testing technique for perforated plate heat exchangers

    NASA Technical Reports Server (NTRS)

    Rodriguez, Jose I.; Mills, Anthony F.

    1990-01-01

    An analysis of the single-blow transient testing technique for heat exchanger surfaces is made for perforated plate and similar discontinuous surfaces. The model assumes that there is no temperature variation across each plate, and allows for axial conduction in spacers: the resulting axial fluid temperature profile is discontinuous, rather than the usual continuous profile. Numerical solutions are obtained to the resulting set of coupled first-order differential equations for a step change in inlet fluid temperature. Results are presented in tabular form, which allow the heat transfer coefficients to be calculated from test data using the maximum slope technique.

  3. Single-Event Transient Testing of the Crane Aerospace and Electronics SMHF2812D Dual DC-DC Converter

    NASA Technical Reports Server (NTRS)

    Casey, Megan

    2015-01-01

    The purpose of this testing was to characterize the Crane Aerospace & Electronics (Crane) Interpoint SMHF2812D for single-event transient (SET) susceptibility. These data shall be used for flight lot evaluation, as well as qualification by similarity of the SMHF family of converters, all of which use the same active components.

  4. Single-Event Transient Testing of Low Dropout PNP Series Linear Voltage Regulators

    NASA Technical Reports Server (NTRS)

    Adell, Philippe; Allen, Gregory

    2013-01-01

    As demand for high-speed, on-board, digital-processing integrated circuits on spacecraft increases (field-programmable gate arrays and digital signal processors in particular), the need for the next generation point-of-load (POL) regulator becomes a prominent design issue. Shrinking process nodes have resulted in core rails dropping to values close to 1.0 V, drastically reducing margin to standard switching converters or regulators that power digital ICs. The goal of this task is to perform SET characterization of several commercial POL converters, and provide a discussion of the impact of these results to state-of-the-art digital processing IC through laser and heavy ion testing

  5. Single Event Transients in Low Voltage Dropout (LVDO) Voltage Regulators

    NASA Technical Reports Server (NTRS)

    LaBel, K.; Karsh, J.; Pursley, S.; Kleyner, I.; Katz, R.; Poivey, C.; Kim, H.; Seidleck, C.

    2006-01-01

    This viewgraph presentation reviews the use of Low Voltage Dropout (LVDO) Voltage Regulators in environments where heavy ion induced Single Event Transients are a concern to the designers.Included in the presentation are results of tests of voltage regulators.

  6. Effect of transient liquid phase (TLP) bonding on the ductility of a Ni-base single crystal superalloy in a stress rupture test

    SciTech Connect

    Liu, J.D. Jin, T.; Zhao, N.R.; Wang, Z.H.; Sun, X.F.; Guan, H.R.; Hu, Z.Q.

    2008-01-15

    A Ni-base single crystal superalloy was transient liquid phase (TLP) bonded using a Ni-Cr-B amorphous foil at 1230 deg. C for 8 h. Stress rupture tests of the TLP joint and a matrix sample were carried out at 982 deg. C/248 MPa and 1010 deg. C/248 MPa. The microstructures and fracture surfaces were studied using scanning electron microscopy (SEM). Transmission electron microscopy (TEM) investigations were performed after creep rupture testing to examine the deformation substructures. The results show that the stress rupture ductility of TLP joints is significantly decreased compared to the matrix sample. This reduction of the ductility of TLP joints can be attributed to solid solution strengthening by boron atoms, subgrain boundaries formed in the bonding zone and the concentration of creep cavities formed during the last stage of the stress rupture test.

  7. Single-Event Transients in Voltage Regulators

    NASA Technical Reports Server (NTRS)

    Johnston, Allan H.; Miyahira, Tetsuo F.; Irom, F.; Laird, Jamie S.

    2006-01-01

    Single-event transients are investigated for two voltage regulator circuits that are widely used in space. A circuit-level model is developed that can be used to determine how transients are affected by different circuit application conditions. Internal protection circuits-which are affected by load as well as internal thermal effects-can also be triggered from heavy ions, causing dropouts or shutdown ranging from milliseconds to seconds. Although conventional output transients can be reduced by adding load capacitance, that approach is ineffective for dropouts from protection circuitry.

  8. Igniter heater EMI transient test

    NASA Technical Reports Server (NTRS)

    Cook, M.

    1989-01-01

    Testing to evaluate Redesigned Solid Rocket Motor igniter heater electromagnetic interference (EMI) effects on the Safe and Arm (S and A) device was completed. It was suspected that EMI generated by the igniter heater and it's associated electromechanical relay could cause a premature firing of the NASA Standard Initiators (NSIs) inside the S and A. The maximum voltage induced into the NSI fire lines was 1/4 of the NASA specified no-fire limit of one volt (SKB 26100066). As a result, the igniter heaters are not expected to have any adverse EMI effects on the NSIs. The results did show, however, that power switching causes occasional high transients within the igniter heater power cable. These transients could affect the sensitive equipment inside the forward skirt. It is therefore recommended that the electromechanical igniter heater relays be replaced with zero crossing solid state relays. If the solid state relays are installed, it is also recommended that they be tested for EMI transient effects.

  9. Transient Pressure Test Article Test Program

    NASA Technical Reports Server (NTRS)

    Vibbart, Charles M.

    1989-01-01

    The Transient Pressure Test Article (TPTA) test program is being conducted at a new test facility located in the East Test Area at the National Aeronautics and Space Administration's (NASA's) Marshall Space Flight Center (MSFC) in Huntsville, Alabama. This facility, along with the special test equipment (STE) required for facility support, was constructed specifically to test and verify the sealing capability of the Redesigned Solid Rocket Motor (RSRM) field, igniter, and nozzle joints. The test article consists of full scale RSRM hardware loaded with inert propellant and assembled in a short stack configuration. The TPTA is pressurized by igniting a propellant cartridge capable of inducing a pressure rise rate which stimulates the ignition transient that occurs during launch. Dynamic loads are applied during the pressure cycle to simulate external tank attach (ETA) strut loads present on the ETA ring. Sealing ability of the redesigned joints is evaluated under joint movement conditions produced by these combined loads since joint sealing ability depends on seal resilience velocity being greater than gap opening velocity. Also, maximum flight dynamic loads are applied to the test article which is either pressurized to 600 psia using gaseous nitrogen (GN2) or applied to the test article as the pressure decays inside the test article on the down cycle after the ignition transient cycle. This new test facility is examined with respect to its capabilities. In addition, both the topic of test effectiveness versus space vehicle flight performance and new aerospace test techniques, as well as a comparison between the old SRM design and the RSRM are presented.

  10. Radiation-induced transient absorption in single mode optical fibers

    SciTech Connect

    Looney, L.D.; Lyons, P.B.

    1988-01-01

    This paper reviews the measurements conducted by the Los Alamos National Laboratory in support of these NATO efforts wherein radiation-induced transient absorption was measured over time ranges from a few ns to several ..mu..s for two single mode fibers. Experimental conditions were varied to provide data for future development of standarized test conditions for single mode fibers. 8 refs., 11 figs.

  11. Analysis and RHBD technique of single event transients in PLLs

    NASA Astrophysics Data System (ADS)

    Zhiwei, Han; Liang, Wang; Suge, Yue; Bing, Han; Shougang, Du

    2015-11-01

    Single-event transient susceptibility of phase-locked loops has been investigated. The charge pump is the most sensitive component of the PLL to SET, and it is hard to mitigate this effect at the transistor level. A test circuit was designed on a 65 nm process using a new system-level radiation-hardening-by-design technique. Heavy-ion testing was used to evaluate the radiation hardness. Analyses and discussion of the feasibility of this method are also presented.

  12. Single Event Transients in Linear Integrated Circuits

    NASA Technical Reports Server (NTRS)

    Buchner, Stephen; McMorrow, Dale

    2005-01-01

    On November 5, 2001, a processor reset occurred on board the Microwave Anisotropy Probe (MAP), a NASA mission to measure the anisotropy of the microwave radiation left over from the Big Bang. The reset caused the spacecraft to enter a safehold mode from which it took several days to recover. Were that to happen regularly, the entire mission would be compromised, so it was important to find the cause of the reset and, if possible, to mitigate it. NASA assembled a team of engineers that included experts in radiation effects to tackle the problem. The first clue was the observation that the processor reset occurred during a solar event characterized by large increases in the proton and heavy ion fluxes emitted by the sun. To the radiation effects engineers on the team, this strongly suggested that particle radiation might be the culprit, particularly when it was discovered that the reset circuit contained three voltage comparators (LM139). Previous testing revealed that large voltage transients, or glitches appeared at the output of the LM139 when it was exposed to a beam of heavy ions [NI96]. The function of the reset circuit was to monitor the supply voltage and to issue a reset command to the processor should the voltage fall below a reference of 2.5 V [PO02]. Eventually, the team of engineers concluded that ionizing particle radiation from the solar event produced a negative voltage transient on the output of one of the LM139s sufficiently large to reset the processor on MAP. Fortunately, as of the end of 2004, only two such resets have occurred. The reset on MAP was not the first malfunction on a spacecraft attributed to a transient. That occurred shortly after the launch of NASA s TOPEX/Poseidon satellite in 1992. It was suspected, and later confirmed, that an anomaly in the Earth Sensor was caused by a transient in an operational amplifier (OP-15) [KO93]. Over the next few years, problems on TDRS, CASSINI, [PR02] SOHO [HA99,HA01] and TERRA were also attributed to transients. In some cases, such events produced resets by falsely triggering circuits designed to protect against over- voltage or over-current. On at least three occasions, transients caused satellites to switch into "safe mode" in which most of the systems on board the satellites were powered down for an extended period. By the time the satellites were reconfigured and returned to full operational state, much scientific data had been lost. Fortunately, no permanent damage occurred in any of the systems and they were all successfully re-activated.

  13. Transient thermoelectric effect in bismuth single crystals

    NASA Astrophysics Data System (ADS)

    Sasaki, M.; Tai, G. X.; Inoue, M.; Bidadi, H.

    1994-05-01

    The photo-induced transient thermoelectric effect (TTE) has been measured for bismuth single crystals along nearly the X and Y axes over the temperature range 6-300 K and time range 50 ns-2 ms. The decay curves of the TTE voltages are characterized by multiple relaxation processes for thermal diffusions of photogenerated electrons and holes. From the analysis of the relaxation times, we have evaluated the carrier mobilities and their effective masses of each carrier pocket at the L and T points based on the existing band model; in particular, we have found an additional hole pocket at the L point lying below the Fermi energy. This TTE technique is shown to be useful for understanding electronic properties of a multicarrier system.

  14. Transient Sub-Poissonian Distribution for Single-Mode Lasers

    NASA Technical Reports Server (NTRS)

    Zang, J. Y.; Gu, Q.; Tian, L. K.

    1996-01-01

    In this paper, the transient photon statistics for single-mode lasers is investigated by making use of the theory of quantum electrodynamics. By taking into account of the transitive time l,we obtain the master equation for Jaynes-Cummings model. The relation between the Mandel factor and the time is obtained by directly solving the master equation. The result shows that a transient phenomenon from the transient super-Poissonian distribution to the transient sub-Poissonian distribution occurs for single-mode lasers. In addition, the influences of the thermal light field and the cavity loss on the transient sub-Poissonian distribution are also studied.

  15. Future Transient Testing of Advanced Fuels

    SciTech Connect

    Jon Carmack

    2009-09-01

    The transient in-reactor fuels testing workshop was held on May 4–5, 2009 at Idaho National Laboratory. The purpose of this meeting was to provide a forum where technical experts in transient testing of nuclear fuels could meet directly with technical instrumentation experts and nuclear fuel modeling and simulation experts to discuss needed advancements in transient testing to support a basic understanding of nuclear fuel behavior under off-normal conditions. The workshop was attended by representatives from Commissariat à l'Énergie Atomique CEA, Japanese Atomic Energy Agency (JAEA), Department of Energy (DOE), AREVA, General Electric – Global Nuclear Fuels (GE-GNF), Westinghouse, Electric Power Research Institute (EPRI), universities, and several DOE national laboratories. Transient testing of fuels and materials generates information required for advanced fuels in future nuclear power plants. Future nuclear power plants will rely heavily on advanced computer modeling and simulation that describes fuel behavior under off-normal conditions. TREAT is an ideal facility for this testing because of its flexibility, proven operation and material condition. The opportunity exists to develop advanced instrumentation and data collection that can support modeling and simulation needs much better than was possible in the past. In order to take advantage of these opportunities, test programs must be carefully designed to yield basic information to support modeling before conducting integral performance tests. An early start of TREAT and operation at low power would provide significant dividends in training, development of instrumentation, and checkout of reactor systems. Early start of TREAT (2015) is needed to support the requirements of potential users of TREAT and include the testing of full length fuel irradiated in the FFTF reactor. The capabilities provided by TREAT are needed for the development of nuclear power and the following benefits will be realized by the refurbishment and restart of TREAT. •TREAT is an absolute necessity in the suite of reactor fuel test capabilities •TREAT yields valuable information on reactivity effects, margins to failure, fuel dispersal, and failure propagation •Most importantly, interpretation of TREAT experiment results is a stringent test of the integrated understanding of fuel performance.

  16. Results from transient tests and spherical valve closure tests, Raccoon Mountain Pumped-Storage Plant

    SciTech Connect

    March, P.A.

    1984-09-01

    Tests were conducted at the Raccoon Mountain Pumped-Storage Plant to obtain data on hydraulic system characteristics during transient-state operation, to compare measured values for system pressures and surge levels with design values, to provide information for review of hydaulic transient computations, and to provide confirmation that the spherical valves are capable of shutting off plant flow under emergency conditions. The tests included single-unit load rejection, single-unit pump power loss, multi-unit emergency shutdown from generating, multi-unit emergency shutdown from pumping, and spherical valve closure.

  17. Sensitive, time-resolved, broadband spectroscopy of single transient processes

    NASA Astrophysics Data System (ADS)

    Fjodorow, Peter; Baev, Ivan; Hellmig, Ortwin; Sengstock, Klaus; Baev, Valery M.

    2015-09-01

    Intracavity absorption spectroscopy with a broadband Er3+-doped fiber laser is applied to time-resolved measurements of transient gain and absorption in electrically excited Xe and Kr plasmas. The achieved time resolution for broadband spectral recording of a single process is 25 µs. For pulsed-periodic processes, the time resolution is limited by the laser pulse duration, which is set here to 3 µs. This pulse duration also predefines the effective absorption path length, which amounts to 900 m. The presented technique can be applied to multicomponent analysis of single transient processes such as shock tube experiments, pulse detonation engines, or explosives.

  18. Transient well testing in two-phase geothermal reservoirs

    SciTech Connect

    Aydelotte, S.R.

    1980-03-01

    A study of well test analysis techniques in two-phase geothermal reservoirs has been conducted using a three-dimensional, two-phase, wellbore and reservoir simulation model. Well tests from Cerro Prieto and the Hawaiian Geothermal project have been history matched. Using these well tests as a base, the influence of reservoir permeability, porosity, thickness, and heat capacity, along with flow rate and fracturing were studied. Single and two-phase transient well test equations were used to analyze these tests with poor results due to rapidly changing fluid properties and inability to calculate the flowing steam saturation in the reservoir. The injection of cold water into the reservoir does give good data from which formation properties can be calculated.

  19. PFR/Treat Safety Experiments: HEDL Transient Test Program Engineering Test Plan

    SciTech Connect

    Hoffman, M.A.; Metcalf, I.L.; Myron, D.L.

    1981-03-01

    The purpose of the PFR/TREAT Safety Test Program is to obtain experimental data of fuel pin behavior during hypothetical, unprotected accidents for cores of large liquid metal cooled fast breeder reactors. The steady state and transient experiments, which will be performed under the joint program, are to be as prototypic of fast reactor performance as is possible. The specific objectives of this document are: (1) dictate the activities and responsibilities for the HEDL Transient Test Program; (2) specify the technical requirements for the CO4, CO5, CO6 and CO7 test train (SPTTs); and (3) specify the technical requirement for the CO6 and CO7 Single Pin Test Loops (SPTLs). Specific requirements for single pin loop experiments beyond CO7 and multi pin experiments will be covered in the addenda to this test plan.

  20. Method and device for measuring single-shot transient signals

    DOEpatents

    Yin, Yan

    2004-05-18

    Methods, apparatus, and systems, including computer program products, implementing and using techniques for measuring multi-channel single-shot transient signals. A signal acquisition unit receives one or more single-shot pulses from a multi-channel source. An optical-fiber recirculating loop reproduces the one or more received single-shot optical pulses to form a first multi-channel pulse train for circulation in the recirculating loop, and a second multi-channel pulse train for display on a display device. The optical-fiber recirculating loop also optically amplifies the first circulating pulse train to compensate for signal losses and performs optical multi-channel noise filtration.

  1. Investigation of Transient Combustion Characteristics in a Single Tubular Combustor

    NASA Technical Reports Server (NTRS)

    Donlon, Richard H; Mccafferty, Richard J; Straight, David M

    1954-01-01

    An investigation was conducted to determine the combustion response to rapid fuel-flow changes in a single tubular combustor at two simulated altitude-rotor speed conditions of 25,000 feet-70 percent rated engine speed and 50,000 feet-70 percent rated engine speed. Limiting rates of change of fuel flow (acceleration limits) were determined and the effects of certain combustion air flow variables on the transient combustion characteristics were studied with the aid of rapid-response instrumentation.

  2. Transient analysis of the 1991 Hijiori Shallow Reservoir Circulation Test

    SciTech Connect

    Hyodo, M.; Shinohara, N.; Takasugi, S.; Wright, C.A.; Conant, R..

    1996-01-24

    Like any dynamic system, HDR reservoirs cannot be fully characterized by their steady-state behavior. Circulation tests analysis should be performed on both the steady-state response and the transient response of HDR systems. Transient analysis allows not only estimation of critical reservoir parameters and how these parameters change with operating conditions / history, but transient analysis also aids in evaluating the feasibility of various modes of HDR system operation (base load, load following, etc.). This paper details the transient analysis of NEDO's FY 1991 Shallow Reservoir Circulation Test at the Hijiori HDR site in Japan. Reservoir fluid storage is carefully bounded through the employment of two distinct methods for calculation of the fluid storage from the observed transient response. A brief discussion is also included of the distribution of reservoir fluid storage; the relationship between pressure, reservoir stress, and apparent reservoir capacitance; and appropriate circulation test design to facilitate transient analysis.

  3. Transient Molecular Transfer During Vacuum Testing

    NASA Technical Reports Server (NTRS)

    Perry, Radford L.

    2011-01-01

    A common question in contamination budgeting involves the loss of collected volatiles during ambient I&T activity under vacuum and the resultant cross-contamination from outgassing. (1) How much of the material collected under ambient conditions evaporates under vacuum? (2) Why do pristine surfaces sometimes show increased molecular contamination after vacuum bakeout? (3) How much of the collected molecular contamination is transient (i.e. migratory) and how much is permanent? Measuring the transient deposition may be accomplished using a thermally passive QCM

  4. Multi-axis transient vibration testing of space objects: Test philosophy, test facility, and control strategy

    NASA Technical Reports Server (NTRS)

    Lachenmayr, Georg

    1992-01-01

    IABG has been using various servohydraulic test facilities for many years for the reproduction of service loads and environmental loads on all kinds of test objects. For more than 15 years, a multi-axis vibration test facility has been under service, originally designed for earthquake simulation but being upgraded to the demands of space testing. First tests with the DFS/STM showed good reproduction accuracy and demonstrated the feasibility of transient vibration testing of space objects on a multi-axis hydraulic shaker. An approach to structural qualification is possible by using this test philosophy. It will be outlined and its obvious advantages over the state-of-the-art single-axis test will be demonstrated by example results. The new test technique has some special requirements to the test facility exceeding those of earthquake testing. Most important is the high reproduction accuracy demanded for a sophisticated control system. The state-of-the-art approach of analog closed-loop control circuits for each actuator combined with a static decoupling network and an off-line iterative waveform control is not able to meet all the demands. Therefore, the future over-all control system is implemented as hierarchical full digital closed-loop system on a highly parallel transputer network. The innermost layer is the digital actuator controller, the second one is the MDOF-control of the table movement. The outermost layer would be the off-line iterative waveform control, which is dedicated only to deal with the interaction of test table and test object or non-linear effects. The outline of the system will be presented.

  5. Space Shuttle solid rocket motor testing for return to flight - Transient Pressure Test Article test program

    NASA Technical Reports Server (NTRS)

    Vibbart, Charles M.

    1988-01-01

    The Transient Pressure Test Article (TPTA) test program, which is being conducted at a new facility at NASA-Marshall, is described. The facility is designed to test and verify the sealing capability of the redesigned solid rocket motor's (RSRM) field, igniter, and nozzle joints. The test article consists of full-scale RSRM hardware loaded with inert propellant and assembled in a short stack configuration. The test facility is described as well as test implementation, test effectiveness, and test results.

  6. Heavy Ion and Proton Induced Single Event Transients in Linear Devices

    NASA Technical Reports Server (NTRS)

    Nichols, D. K.; Coss, J. R.; Miyahira, T.; Schwartz, H. R.

    1996-01-01

    This paper presents a display of heavy-ion and proton-induced single event transients for selected linear devices. The transient vital signs are serious; low LET threshold, high voltage amplitude and extended pulse duration (microsecs.).

  7. See Change: Classifying single observation transients from HST using SNCosmo

    NASA Astrophysics Data System (ADS)

    Sofiatti Nunes, Caroline; Perlmutter, Saul; Nordin, Jakob; Rubin, David; Lidman, Chris; Deustua, Susana E.; Fruchter, Andrew S.; Aldering, Greg Scott; Brodwin, Mark; Cunha, Carlos E.; Eisenhardt, Peter R.; Gonzalez, Anthony H.; Jee, Myungkook J.; Hildebrandt, Hendrik; Hoekstra, Henk; Santos, Joana; Stanford, S. Adam; Stern, Dana R.; Fassbender, Rene; Richard, Johan; Rosati, Piero; Wechsler, Risa H.; Muzzin, Adam; Willis, Jon; Boehringer, Hans; Gladders, Michael; Goobar, Ariel; Amanullah, Rahman; Hook, Isobel; Huterer, Dragan; Huang, Jiasheng; Kim, Alex G.; Kowalski, Marek; Linder, Eric; Pain, Reynald; Saunders, Clare; Suzuki, Nao; Barbary, Kyle H.; Rykoff, Eli S.; Meyers, Joshua; Spadafora, Anthony L.; Hayden, Brian; Wilson, Gillian; Rozo, Eduardo; Hilton, Matt; Dixon, Samantha; Yen, Mike

    2016-01-01

    The Supernova Cosmology Project (SCP) is executing "See Change", a large HST program to look for possible variation in dark energy using supernovae at z>1. As part of the survey, we often must make time-critical follow-up decisions based on multicolor detection at a single epoch. We demonstrate the use of the SNCosmo software package to obtain simulated fluxes in the HST filters for type Ia and core-collapse supernovae at various redshifts. These simulations allow us to compare photometric data from HST with the distribution of the simulated SNe through methods such as Random Forest, a learning method for classification, and Gaussian Kernel Estimation. The results help us make informed decisions about triggered follow up using HST and ground based observatories to provide time-critical information needed about transients. Examples of this technique applied in the context of See Change are shown.

  8. Thermal-Transient Testing Of Turbine Blades

    NASA Technical Reports Server (NTRS)

    Wagner, William R.; Pidcoke, Louis H.

    1990-01-01

    Testing apparatus applies pulses of heat to turbine blade to determine resistance to thermal fatigue. Uses nonintrusive inductive heating and records distribution of temperature on blade with infrared video camera. Allows precise control of heating and cooling. Designed for testing blades used in advanced high-pressure, high-temperature turbines.

  9. Investigations on heavy ion induced Single-Event Transients (SETs) in highly-scaled FinFETs

    NASA Astrophysics Data System (ADS)

    Gaillardin, M.; Raine, M.; Paillet, P.; Adell, P. C.; Girard, S.; Duhamel, O.; Andrieu, F.; Barraud, S.; Faynot, O.

    2015-12-01

    We investigate Single-Event Transients (SET) in different designs of multiple-gate devices made of FinFETs with various geometries. Heavy ion experimental results are explained by using a thorough charge collection analysis of fast transients measured on dedicated test structures. Multi-level simulations are performed to get new insights into the charge collection mechanisms in multiple-gate devices. Implications for multiple-gate device design hardening are finally discussed.

  10. Transient Positive Horizontal Head Impulse Test in Pregabalin Intoxication.

    PubMed

    Jeong, Seong-Hae; Kim, Yong Soo; Lee, Ju-Hoen; Jo, Hyunjin; Lee, Ae Young; Kim, Jae-Moon

    2015-12-01

    Head impulse test (HIT) is helpful to understanding high-frequency vestibulo-ocular reflex in patients with dizziness and imbalance. There are some reports on abnormal HITs in cerebellar disorder. To our knowledge, there was no report of transient bilateral positive head impulse related to antiepileptic drugs. A 65-year-old woman developed dizziness and imbalance after treatment with pregabalin for pain control of radiation cystitis. Neurological examination exhibited positive bilateral HIT results, in addition to ataxia and gaze-evoked rebound nystagmus. Pregabalin intoxication can evoke transient positive horizontal head impulse test as another indicator of cerebellar dysfunction. PMID:26819943

  11. Alternatives Analysis for the Resumption of Transient Testing Program

    SciTech Connect

    Lee Nelson

    2013-11-01

    An alternatives analysis was performed for resumption of transient testing. The analysis considered eleven alternatives including both US international facilities. A screening process was used to identify two viable alternatives from the original eleven. In addition, the alternatives analysis includes a no action alternative as required by the National Environmental Policy Act (NEPA). The alternatives considered in this analysis included: 1. Restart the Transient Reactor Test Facility (TREAT) 2. Modify the Annular Core Research Reactor (ACRR) which includes construction of a new hot cell and installation of a new hodoscope. 3. No Action

  12. Transient Positive Horizontal Head Impulse Test in Pregabalin Intoxication

    PubMed Central

    Jeong, Seong-Hae; Kim, Yong Soo; Lee, Ju-Hoen; Jo, Hyunjin; Lee, Ae Young; Kim, Jae-Moon

    2015-01-01

    Head impulse test (HIT) is helpful to understanding high-frequency vestibulo-ocular reflex in patients with dizziness and imbalance. There are some reports on abnormal HITs in cerebellar disorder. To our knowledge, there was no report of transient bilateral positive head impulse related to antiepileptic drugs. A 65-year-old woman developed dizziness and imbalance after treatment with pregabalin for pain control of radiation cystitis. Neurological examination exhibited positive bilateral HIT results, in addition to ataxia and gaze-evoked rebound nystagmus. Pregabalin intoxication can evoke transient positive horizontal head impulse test as another indicator of cerebellar dysfunction. PMID:26819943

  13. Plasma-Catalysis During Temperature Transient Testing

    SciTech Connect

    Hoard, John

    2001-08-05

    A combination of catalysts is used together with nonthermal plasma in simulated diesel exhaust, while the gas temperature is varied. The catalysts both store and convert pollutants. As a result, pollutant concentrations during temperature ramps are different than those at steady state conditions. The data are presented for plasma followed by BaY, alumina, and Pt catalysts in simulated exhaust. When temperature ramps from high to low, apparent NOx conversion is quite high. However, when temperature is ramped from low to high, lower apparent conversions are seen. In a typical test cycle, average NOx conversion between 100 and 400 C is 60%. Peak conversion during the down ramp is over 90%, and minimum conversion during the up ramp is 30%. The composition of the effluent gas also varies during the temperature cycle. Intermediates such as methyl nitrate and hydrogen cyanide are not present following the combination of catalysts.

  14. SINGLE FIBER TESTING VIA FAVIMAT

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Cotton fiber is usually tested in bulk form utilizing a mass or beard of fibers to be presented to a test instrument for measurement. There are many reasons for this, not the least of which is that handling single cotton fibers is tedious and time consuming. Cotton breeders are being pushed to mak...

  15. Recording and time expansion technique for high-speed, single-shot transient video signal

    NASA Technical Reports Server (NTRS)

    Hruby, R. J.; Sander, R. C.

    1967-01-01

    High-speed, single-shot, transient voltage is recorded on a video tape recorder, which, when played back, converts the single signal to a repetitive signal. This drives a sample data translator which lengthens the original transient production time, suiting it to an x-y plotter or computer tape recorder use.

  16. A Technique for Transient Thermal Testing of Thick Structures

    NASA Technical Reports Server (NTRS)

    Horn, Thomas J.; Richards, W. Lance; Gong, Leslie

    1997-01-01

    A new open-loop heat flux control technique has been developed to conduct transient thermal testing of thick, thermally-conductive aerospace structures. This technique uses calibration of the radiant heater system power level as a function of heat flux, predicted aerodynamic heat flux, and the properties of an instrumented test article. An iterative process was used to generate open-loop heater power profiles prior to each transient thermal test. Differences between the measured and predicted surface temperatures were used to refine the heater power level command profiles through the iteration process. This iteration process has reduced the effects of environmental and test system design factors, which are normally compensated for by closed-loop temperature control, to acceptable levels. The final revised heater power profiles resulted in measured temperature time histories which deviated less than 25 F from the predicted surface temperatures.

  17. SINGLE HEATER TEST FINAL REPORT

    SciTech Connect

    J.B. Cho

    1999-05-01

    The Single Heater Test is the first of the in-situ thermal tests conducted by the U.S. Department of Energy as part of its program of characterizing Yucca Mountain in Nevada as the potential site for a proposed deep geologic repository for the disposal of spent nuclear fuel and high-level nuclear waste. The Site Characterization Plan (DOE 1988) contained an extensive plan of in-situ thermal tests aimed at understanding specific aspects of the response of the local rock-mass around the potential repository to the heat from the radioactive decay of the emplaced waste. With the refocusing of the Site Characterization Plan by the ''Civilian Radioactive Waste Management Program Plan'' (DOE 1994), a consolidated thermal testing program emerged by 1995 as documented in the reports ''In-Situ Thermal Testing Program Strategy'' (DOE 1995) and ''Updated In-Situ Thermal Testing Program Strategy'' (CRWMS M&O 1997a). The concept of the Single Heater Test took shape in the summer of 1995 and detailed planning and design of the test started with the beginning fiscal year 1996. The overall objective of the Single Heater Test was to gain an understanding of the coupled thermal, mechanical, hydrological, and chemical processes that are anticipated to occur in the local rock-mass in the potential repository as a result of heat from radioactive decay of the emplaced waste. This included making a priori predictions of the test results using existing models and subsequently refining or modifying the models, on the basis of comparative and interpretive analyses of the measurements and predictions. A second, no less important, objective was to try out, in a full-scale field setting, the various instruments and equipment to be employed in the future on a much larger, more complex, thermal test of longer duration, such as the Drift Scale Test. This ''shake down'' or trial aspect of the Single Heater Test applied not just to the hardware, but also to the teamwork and cooperation between multiple organizations performing their part in the test.

  18. Parametric Thermal Models of the Transient Reactor Test Facility (TREAT)

    SciTech Connect

    Bradley K. Heath

    2014-03-01

    This work supports the restart of transient testing in the United States using the Department of Energy’s Transient Reactor Test Facility at the Idaho National Laboratory. It also supports the Global Threat Reduction Initiative by reducing proliferation risk of high enriched uranium fuel. The work involves the creation of a nuclear fuel assembly model using the fuel performance code known as BISON. The model simulates the thermal behavior of a nuclear fuel assembly during steady state and transient operational modes. Additional models of the same geometry but differing material properties are created to perform parametric studies. The results show that fuel and cladding thermal conductivity have the greatest effect on fuel temperature under the steady state operational mode. Fuel density and fuel specific heat have the greatest effect for transient operational model. When considering a new fuel type it is recommended to use materials that decrease the specific heat of the fuel and the thermal conductivity of the fuel’s cladding in order to deal with higher density fuels that accompany the LEU conversion process. Data on the latest operating conditions of TREAT need to be attained in order to validate BISON’s results. BISON’s models for TREAT (material models, boundary convection models) are modest and need additional work to ensure accuracy and confidence in results.

  19. Analysis of Transient Pressure Tests for Olkaria Exploration Wells

    SciTech Connect

    Haukwa, Charles B.

    1987-01-20

    Analysis of transient pressure tests for Olkaria West wells shows that both infinite acting and double porosity models can be used to analyze the well behaviour and infer reservoir properties from fall-off steps of long enough duration, in wells where no significant thermal recovery occurs. The double porosity model gives better estimates of reservoir properties than the infinite acting model, for long fall-off steps in wells intercepting fractures. Semilog methods give fairly good estimates of reservoir transmissivity for the long fall-off steps but are highly inaccurate when used independently, especially for the short fall-off steps conducted in most of the wells. Double porosity models can also be used for recovery test analyses where two phase transients are not significant. 6 refs., 11 figs., 8 tabs.

  20. Electromagnetic transients in substations. Volume 3, Test results: Final report

    SciTech Connect

    Wiggins, C.M.; Nickel, F.S.; Salas, T.M.; Thomas, D.E.

    1993-04-01

    High frequency transient electromagnetic interference (EMI) caused by faults, lightning, and switching on high voltage circuits in substations is characterized and quantified using a mobile four-channel transient EMI measurements system and validated traveling wave transient analysis models. More than 800 waveforms of high voltage switching transients and staged-faults were measured in air- and gas-insulated substations and used to validate a system of interrelated substation interference coupling models. The highest transient EMI levels expected from initial conditions of 2PU (Per Unit) disconnect switching, a 2PU circuit breaker fault, and a 10 kA lightning strike inside substations through 500 kV are calculated using the models. These initial conditions, believed to be nominally worst case for these three high voltage EMI sources, are defined as follows. For disconnect switching, the 2PU initial condition represents the maximum peak phase-to-ground voltage that can occur across a switch gap restriking at its greatest separation. An initial condition of 2PU peak phase-to-ground voltage can occur on an open and adjacent substation bus during switching from a remote location. A 10 kA lightning strike represents the maximum current expected to be attached directly to a 500 kV bus as a result of a shielding failure. Volume 1 of this report contains a summary and recommendations; volume 2 covers the computer models; volume 3 provides detailed results of the interference tests; and volumes 4 and 5, available on demand, contain data logs, raw data plots, and digital waveforms.

  1. Polarity Switching and Transient Responses in Single Nanotube Nanofluidic Transistors

    NASA Astrophysics Data System (ADS)

    Fan, Rong; Yue, Min; Karnik, Rohit; Majumdar, Arun; Yang, Peidong

    2005-08-01

    We report the integration of inorganic nanotubes into metal-oxide-solution field effect transistors (FETs) which exhibit rapid field effect modulation of ionic conductance. Surface functionalization, analogous to doping in semiconductors, can switch the nanofluidic transistors from p-type to ambipolar and n-type field effect transistors. Transient study reveals the kinetics of field effect modulation is controlled by ion-exchange step. Nanofluidic FETs have potential implications in subfemtoliter analytical technology and large-scale nanofluidic integration.

  2. Tidal volume single-breath washin of SF6 and CH4 in transient microgravity

    NASA Technical Reports Server (NTRS)

    Dutrieue, Brigitte; Paiva, Manuel; Verbanck, Sylvia; Le Gouic, Marine; Darquenne, Chantal; Prisk, G. Kim

    2003-01-01

    We performed tidal volume single-breath washins (SBW) by using tracers of different diffusivity and varied the time spent in microgravity (microG) before the start of the tests to look for time-dependent effects. SF(6) and CH(4) phase III slopes decreased by 35 and 26%, respectively, in microG compared with 1 G (P < 0.05), and the slope difference between gases disappeared. There was no effect of time in microG, suggesting that neither the hypergravity period preceding microG nor the time spent in microG affected gas mixing at volumes near functional residual capacity. In previous studies using SF(6) and He (Lauzon A-M, Prisk GK, Elliott AR, Verbanck S, Paiva M, and West JB. J Appl Physiol 82: 859-865, 1997), the vital capacity SBW showed an increase in slope difference between gases in transient microG, the opposite of the decrease in sustained microG. In contrast, tidal volume SBW showed a decrease in slope difference in both microG conditions. Because it is only the behavior of the more diffusive gas that differed between maneuvers and microG conditions, we speculate that, in the previous vital capacity SBW, the hypergravity period preceding the test in transient microG provoked conformational changes at low lung volumes near the acinar entrance.

  3. Large transient fault current test of an electrical roll ring

    NASA Technical Reports Server (NTRS)

    Yenni, Edward J.; Birchenough, Arthur G.

    1992-01-01

    The space station uses precision rotary gimbals to provide for sun tracking of its photoelectric arrays. Electrical power, command signals and data are transferred across the gimbals by roll rings. Roll rings have been shown to be capable of highly efficient electrical transmission and long life, through tests conducted at the NASA Lewis Research Center and Honeywell's Satellite and Space Systems Division in Phoenix, AZ. Large potential fault currents inherent to the power system's DC distribution architecture, have brought about the need to evaluate the effects of large transient fault currents on roll rings. A test recently conducted at Lewis subjected a roll ring to a simulated worst case space station electrical fault. The system model used to obtain the fault profile is described, along with details of the reduced order circuit that was used to simulate the fault. Test results comparing roll ring performance before and after the fault are also presented.

  4. Transient rotor dynamic rub phenomena - Theory and test

    NASA Technical Reports Server (NTRS)

    Kascak, A. F.; Montaque, G.; Palazzolo, A. B.

    1987-01-01

    This paper develops an implicit integration scheme for transient rotor dynamic rub prediction and includes a correlation study with actual test results. A Nordsieck-like numerical integration scheme is applied directly to the second-order equations of motion. The assumption that forces and torques on the rotor are functions of the position and velocity at the point of application and its nearest neighbor is made in order to make the computational time proportional to the number of elements in the rotor dynamics model rather than the cube of the number. The test rig consists of a turbine driven, flexible shaft supported by squeeze film dampers. The blade loss event occurs due to collision of a balance bolt on one of the disks with a high speed plunger. The rotor is seen to spiral outward and contact against a stationary assemblage of seal shoes.

  5. Single Event Transients in Voltage Regulators for FPGA Power Supply Applications

    NASA Technical Reports Server (NTRS)

    Poivey, Christian; Sanders, Anthony; Kim, Hak; Phan, Anthony; Forney, Jim; LaBel, Kenneth A.; Karsh, Jeremy; Pursley, Scott; Kleyner, Igor; Katz, Richard

    2006-01-01

    As with other bipolar analog devices, voltage regulators are known to be sensitive to single event transients (SET). In typical applications, large output capacitors are used to provide noise immunity. Therefore, since SET amplitude and duration are generally small, they are often of secondary importance due to this capacitance filtering. In low voltage applications, however, even small SET are a concern. Over-voltages may cause destructive conditions. Under-voltages may cause functional interrupts and may also trigger electrical latchup conditions. In addition, internal protection circuits which are affected by load as well as internal thermal effects can also be triggered from heavy ions, causing dropouts or shutdown ranging from milliseconds to seconds. In the case of FPGA power supplies applications, SETS are critical. For example, in the case of Actel FPGA RTAX family, core power supply voltage is 1.5V. Manufacturer specifies an absolute maximum rating of 1.6V and recommended operating conditions between 1.425V and 1.575V. Therefore, according to the manufacturer, any transient of amplitude greater than 75 mV can disrupt normal circuit functions, and overvoltages greater than 100 mV may damage the FPGA. We tested five low dropout voltage regulators for SET sensitivity under a large range of circuit application conditions.

  6. Two-dimensional steady-state and transient analysis of single-cell thermionic fuel elements

    SciTech Connect

    El-Genk, M.S.; Xue, H. . Inst. for Space Nuclear Power Studies)

    1994-10-01

    A two-dimensional transient model is developed to simulate steady-state and transient operations of single-cell thermionic fuel elements (TFEs). Model predictions are in good agreement with published data to within 4.5 and 5.5% for fission and electrically heated TFEs of the TOPAZ-II type, respectively. In addition, the results of a transient analysis simulating the startup of an electrically heated TFE, following a step function increase in thermal power, are in presented and discussed.

  7. Transient Analysis Used to Study Thermal Radiation Effects in Single and Composite Semitransparent Layers

    NASA Technical Reports Server (NTRS)

    1996-01-01

    In a continuing in-house program at the NASA Lewis Research Center, analytical and numerical methods are being developed to apply radiative analysis to predict transient temperature distributions and heat flows in partially transmitting materials. Results have been obtained for a single plane layer, and a transient analysis is being developed for a two-layer composite where each layer has a different refractive index. Because the ceramic refractive indices are larger than one, internal reflections are produced at the surfaces and at the internal interface. Reflections tend to distribute energy within a layer, and this affects the transient temperature distributions.

  8. Transient Liquid Phase Bonding Single-Crystal Superalloys with Orientation Deviations: Creep Properties

    NASA Astrophysics Data System (ADS)

    Sheng, Naicheng; Liu, Jide; Jin, Tao; Sun, Xiaofeng; Hu, Zhuangqi

    2015-12-01

    Superalloys single crystals with various orientation deviations were bonded using transient liquid phase bonding method, then the creep properties of the bonded specimens were tested at 1033 K (760 °C)/780 MPa. It is found that the creep life of the bonded specimens decreases with the increase of the relative orientation deviations. Despite the fracture of the specimens appears on the bonding region, the deformation mechanism changes from specimens with low angle boundary to high angle boundary. In low angle boundary specimens, cleavage originated from the defects grows perpendicularly to the tensile stress and connects through the different slip planes around the cleavage planes. In this case, the deformation proceeds by the dislocations and stacking faults on multi-planes. With increasing orientation deviation, dislocation and stacking faults moved on single plane. As a result, the dislocations interact with the grain boundary and lead to fracture. Based on the present investigation, the orientation of the bonded superalloys single crystal should be controlled so that the introduced grain boundaries are relatively small and exhibit higher creep strength.

  9. Transient Testing of Nuclear Fuels and Materials in United States

    SciTech Connect

    Daniel M. Wachs

    2012-12-01

    The US Department of Energy (DOE) has been engaged in an effort to develop and qualify next generation LWR fuel with enhanced performance and safety and reduced waste generation since 2010. This program, which has emphasized collaboration between the DOE, U.S. national laboratories and nuclear industry, was refocused from enhanced performance to enhanced accident tolerance following the events at Fukushima in 2011. Accident tolerant fuels have been specifically described as fuels that, in comparison with standard UO2-Zircaloy, can tolerate loss of active cooling in the reactor core for a considerably longer time period (depending on the LWR system and accident scenario) while maintaining or improving the fuel performance during normal operations, operational transients, as well as design-basis and beyond design-basis events. The program maintains an ambitious goal to insert a lead test assembly (LTA) of the new design into a commercial power reactor by 2022 .

  10. Irisin in Blood Increases Transiently after Single Sessions of Intense Endurance Exercise and Heavy Strength Training

    PubMed Central

    Nygaard, Håvard; Slettaløkken, Gunnar; Vegge, Geir; Hollan, Ivana; Whist, Jon Elling; Strand, Tor; Rønnestad, Bent R.; Ellefsen, Stian

    2015-01-01

    Purpose Irisin is a recently identified exercise-induced hormone that increases energy expenditure, at least in rodents. The main purpose of this study was to test the hypothesis that Irisin increases acutely in blood after singular sessions of intense endurance exercise (END) and heavy strength training (STR). Secondary, we wanted to explore the relationship between body composition and exercise-induced effects on irisin, and the effect of END and STR on muscular expression of the irisin gene FNDC5. Methods Nine moderately trained healthy subjects performed three test days using a randomized and standardized crossover design: one day with 60 minutes of END, one day with 60 minutes of STR, and one day without exercise (CON). Venous blood was sampled over a period of 24h on the exercise days. Results Both END and STR led to transient increases in irisin concentrations in blood, peaking immediately after END and one hour after STR, before gradually returning to baseline. Irisin responses to STR, but not END, showed a consistently strong negative correlation with proportions of lean body mass. Neither END nor STR affected expression of FNDC5, measured 4h after training sessions, though both protocols led to pronounced increases in PGC-1α expression, which is involved in transcriptional control of FNDC5. Conclusion The results strongly suggest that single sessions of intense endurance exercise and heavy strength training lead to transient increases in irisin concentrations in blood. This was not accompanied by increased FNDC5 expression, measured 4h post-exercise. The results suggest that irisin responses to resistance exercise are higher in individuals with lower proportions of lean body mass. PMID:25781950

  11. Transient productivity index for numerical well test simulations

    SciTech Connect

    Blanc, G.; Ding, D.Y.; Ene, A.

    1997-08-01

    The most difficult aspect of numerical simulation of well tests is the treatment of the Bottom Hole Flowing (BHF) Pressure. In full field simulations, this pressure is derived from the Well-block Pressure (WBP) using a numerical productivity index which accounts for the grid size and permeability, and for the well completion. This productivity index is calculated assuming a pseudo-steady state flow regime in the vicinity of the well and is therefore constant during the well production period. Such a pseudo-steady state assumption is no longer valid for the early time of a well test simulation as long as the pressure perturbation has not reached several grid-blocks around the well. This paper offers two different solutions to this problem: (1) The first one is based on the derivation of a Numerical Transient Productivity Index (NTPI) to be applied to Cartesian grids; (2) The second one is based on the use of a Corrected Transmissibility and Accumulation Term (CTAT) in the flow equation. The representation of the pressure behavior given by both solutions is far more accurate than the conventional one as shown by several validation examples which are presented in the following pages.

  12. TRANSPA: a code for transient thermal analysis of a single fuel pin

    SciTech Connect

    Prenger, F.C.

    1985-02-01

    An analytical model (TRANSPA) for the transient thermal analysis of a single uranium carbide fuel pin was developed. This model uses thermal boundary conditions obtained from COBRA-WC output and calculates the transient thermal response of a single fuel pin to changes in internal power generation, coolant flowrate, or fuel pin physical configuration. The model uses the MITAS finite difference thermal analyzer. MITAS provides the means to input separate conductance models through the use of a user subroutine input capability. The model is a lumped-mass representation of the fuel pin using 26 nodes and 42 conductors. Run time for each transient analysis is approximately one minute of central processor time on the NOS operating system.

  13. Barometric pressure transient testing applications at the Nevada Test Site: formation permeability analysis. Final report

    SciTech Connect

    Hanson, J.M.

    1984-12-01

    The report evaluates previous investigations of the gas permeability of the rock surrounding emplacement holes at the Nevada Test Site. The discussion sets the framework from which the present uncertainty in gas permeability can be overcome. The usefulness of the barometric pressure testing method has been established. Flow models were used to evaluate barometric pressure transients taken at NTS holes U2fe, U19ac and U20ai. 31 refs., 103 figs., 18 tabs. (ACR)

  14. Revisiting single photon avalanche diode current-voltage modeling and transient characteristics

    SciTech Connect

    Javitt, M.; Savuskan, V. Merhav, T.; Nemirovsky, Y.

    2014-05-28

    A model for the current-voltage and transient behavior of Single Photon Avalanche Diodes (SPADs) based on device physics is presented. The results of the model are compared to actual measurements and a reasonable fit is seen. Additionally, the model provides a useful tool for designing quenching circuitry and determining optimal operation conditions of the SPAD.

  15. An analog cell to detect single event transients in voltage references

    NASA Astrophysics Data System (ADS)

    Franco, F. J.; Palomar, C.; Izquierdo, J. G.; Agapito, J. A.

    2015-01-01

    A reliable voltage reference is mandatory in mixed-signal systems. However, this family of components can undergo very long single event transients when operating in radiation environments such as space and nuclear facilities due to the impact of heavy ions. The purpose of the present paper is to demonstrate how a simple cell can be used to detect these transients. The cell was implemented with typical COTS components and its behavior was verified by SPICE simulations and in a laser facility. Different applications of the cell are explored as well.

  16. Inducing Transient Charge State of a Single Water Cluster on Cu(111) Surface.

    PubMed

    Guo, Yang; Ding, Zijing; Sun, Lihuan; Li, Jianmei; Meng, Sheng; Lu, Xinghua

    2016-04-26

    The hydrated electron on solid surface is a crucial species to interfacial chemistry. We present a joint low-temperature scanning tunneling microscopy and density functional theory investigation to explore the existence of a transient hydrated electron state induced by injecting tunneling electrons into a single water nonamer cluster on Cu(111) surface. The directional diffusion of water cluster under the Coulomb repulsive potential has been observed as evidence for the emergence of the transient hydrated electron. A critical structure transformation in water cluster for the emergence of hydrated electron has been identified. A charging mechanism has been proposed based on density functional theory calculation and scanning tunneling microscope results. PMID:27007702

  17. Transient thermal dissipation method for xylem sap flow measurement: implementation with a single probe.

    PubMed

    Do, F C; Isarangkool Na Ayutthaya, S; Rocheteau, A

    2011-04-01

    Comparisons of tree water relations between treatments, species and sites are facilitated by the use of simple and low-cost measurements of xylem sap flow rates. The transient thermal dissipation (TTD) method is a variant of the constant thermal dissipation (CTD) method of Granier. It has the advantages of limiting thermal interference and of saving electrical energy. Here, our concern was to test a new step towards simplicity and low cost: the applicability of the TTD method with a single probe, i.e., without a reference sensor, following a cycle of 10 min heating and 10 min cooling, and using the same thermal index and multi-species calibration previously assessed with a dual probe. First, the responses of the dual and single probes were compared in an artificial hydraulic column of sawdust in the laboratory over a complete range of flux densities, from 0.3 to 4.0 l dm? h?. Second, diurnal kinetics were compared in a young tree with rapid changes in the sapwood reference temperature of up to 5 C h? for 5 consecutive days. With a relatively stable reference temperature, laboratory results showed that a single probe yielded the same temperature signal and thermal index as a dual probe for the full range of sap flux densities. Within the tree, the cooled temperature of the heated probe, linearly interpolated, proved to be an accurate indicator of the change in the reference temperature over time. Logically, the temperature signals and estimates of sap flux density with the single probe did not differ from the dual-sensor measurements when the cooled temperature was interpolated. Additionally, the responses of the thermal index, yielded in the hydraulic experiment with the sawdust column, fell within the variability of the multi-species calibration. This result supports the previous assessment of a non-species-specific calibration for the TTD method with diffuse porous media. In conclusion, our results showed that the TTD method can be directly applied with a single probe. Limitations and possible future progress are pointed out. This measurement system is probably the simplest technique currently available to measure xylem sap flow. PMID:21498407

  18. Single Event Transient Analysis of an SOI Operational Amplifier for Use in Low-Temperature Martian Exploration

    NASA Technical Reports Server (NTRS)

    Laird, Jamie S.; Scheik, Leif; Vizkelethy, Gyorgy; Mojarradi, Mohammad M; Chen, Yuan; Miyahira, Tetsuo; Blalock, Benjamin; Greenwell, Robert; Doyle, Barney

    2006-01-01

    The next generation of Martian rover#s to be launched by JPL are to examine polar regions where temperatures are extremely low and the absence of an earth-like atmosphere results in high levels of cosmic radiation at ground level. Cosmic rays lead to a plethora of radiation effects including Single Event Transients (SET) which can severely degrade microelectronic functionality. As such, a radiation-hardened, temperature compensated CMOS Single-On-Insulator (SOI) Operational Amplifier has been designed for JPL by the University of Tennessee and fabricated by Honeywell using the SOI V process. SOI technology has been shownto be far less sensitive to transient effects than both bulk and epilayer Si. Broad beam heavy-ion tests at the University of Texas A&M using Kr and Xebeams of energy 25MeV/amu were performed to ascertain the duration and severity of the SET for the op-amp configured for a low and high gain application. However, some ambiguity regarding the location of transient formation required the use of a focused MeV ion microbeam. A 36MeV O6(+) microbeam. the Sandia National Laboratory (SNL) was used to image and verify regions of particular concern. This is a viewgraph presentation

  19. Preliminary Analysis of the Transient Reactor Test Facility (TREAT) with PROTEUS

    SciTech Connect

    Connaway, H. M.; Lee, C. H.

    2015-11-30

    The neutron transport code PROTEUS has been used to perform preliminary simulations of the Transient Reactor Test Facility (TREAT). TREAT is an experimental reactor designed for the testing of nuclear fuels and other materials under transient conditions. It operated from 1959 to 1994, when it was placed on non-operational standby. The restart of TREAT to support the U.S. Department of Energy’s resumption of transient testing is currently underway. Both single assembly and assembly-homogenized full core models have been evaluated. Simulations were performed using a historic set of WIMS-ANL-generated cross-sections as well as a new set of Serpent-generated cross-sections. To support this work, further analyses were also performed using additional codes in order to investigate particular aspects of TREAT modeling. DIF3D and the Monte-Carlo codes MCNP and Serpent were utilized in these studies. MCNP and Serpent were used to evaluate the effect of geometry homogenization on the simulation results and to support code-to-code comparisons. New meshes for the PROTEUS simulations were created using the CUBIT toolkit, with additional meshes generated via conversion of selected DIF3D models to support code-to-code verifications. All current analyses have focused on code-to-code verifications, with additional verification and validation studies planned. The analysis of TREAT with PROTEUS-SN is an ongoing project. This report documents the studies that have been performed thus far, and highlights key challenges to address in future work.

  20. Single pellet crush strength testing of catalysts

    SciTech Connect

    Brienza, P.K. )

    1988-09-01

    ASTM D-32 Committee on Catalysts has developed a standard test method for single pellet crush strength for formed catalyst shapes. This standard was issued under the fixed designation D 4179. The method is applicable to regular catalyst shapes such as tablets and spheres. Extrudates, granular materials, and other irregular shapes are excluded. The committee continues to work on the development of a method for the single pellet crush testing of extrudates.

  1. 40 CFR Appendix I to Part 1037 - Heavy-Duty Transient Chassis Test Cycle

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 34 2013-07-01 2013-07-01 false Heavy-Duty Transient Chassis Test Cycle I Appendix I to Part 1037 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW HEAVY-DUTY MOTOR VEHICLES Pt. 1037, App. I Appendix I to Part 1037—Heavy-Duty Transient...

  2. Transient currents of a single molecular junction with a vibrational mode

    NASA Astrophysics Data System (ADS)

    Ding, Guo-Hui; Xiong, Bo; Dong, Bing

    2016-02-01

    By using a propagation scheme for current matrices and an auxiliary mode expansion method, we investigate the transient dynamics of a single molecular junction coupled with a vibrational mode. Our approach is based on the spinless AndersonHolstein model and the dressed tunnelling approximation for the electronic self-energy in the polaronic regime. The time-dependent currents after a sudden switching on the tunnelling to leads, an abrupt upward step bias pulse and a step potential on the quantum dot are calculated. We show that the strong electronphonon interaction greatly influences the nonlinear response properties of the system, and gives rise to interesting characteristics on the time traces of transient currents.

  3. Transient currents of a single molecular junction with a vibrational mode.

    PubMed

    Ding, Guo-Hui; Xiong, Bo; Dong, Bing

    2016-02-17

    By using a propagation scheme for current matrices and an auxiliary mode expansion method, we investigate the transient dynamics of a single molecular junction coupled with a vibrational mode. Our approach is based on the spinless Anderson-Holstein model and the dressed tunnelling approximation for the electronic self-energy in the polaronic regime. The time-dependent currents after a sudden switching on the tunnelling to leads, an abrupt upward step bias pulse and a step potential on the quantum dot are calculated. We show that the strong electron-phonon interaction greatly influences the nonlinear response properties of the system, and gives rise to interesting characteristics on the time traces of transient currents. PMID:26795556

  4. Comparison of Single-Event Transients Induced in an Operational Amplifier (LM124) by Pulsed Laser Light and a Broad Beam of Heavy Ions

    NASA Technical Reports Server (NTRS)

    Buchner, Steve; McMorrow, Dale; Poivey, Christian; Howard, James, Jr.; Pease, Rom; Savage, Mark; Boulghassoul, Younis; Massengill, Lloyd

    2003-01-01

    A comparison of transients from heavy-ion and pulsed-laser testing shows good agreement for many different voltage configurations. The agreement is illustrated by comparing directly individual transients and plots of transient amplitude versus width.

  5. Single Event Effect (SEE) Test Planning 101

    NASA Technical Reports Server (NTRS)

    LaBel, Kenneth A.; Pellish, Jonathan; Berg, Melanie D.

    2011-01-01

    This is a course on SEE Test Plan development. It is an introductory discussion of the items that go into planning an SEE test that should complement the SEE test methodology used. Material will only cover heavy ion SEE testing and not proton, LASER, or other though many of the discussed items may be applicable. While standards and guidelines for how-to perform single event effects (SEE) testing have existed almost since the first cyclotron testing, guidance on the development of SEE test plans has not been as easy to find. In this section of the short course, we attempt to rectify this lack. We consider the approach outlined here as a "living" document: mission specific constraints and new technology related issues always need to be taken into account. We note that we will use the term "test planning" in the context of those items being included in a test plan.

  6. Mechanism of single-event transient pulse quenching between dummy gate isolated logic nodes

    NASA Astrophysics Data System (ADS)

    Chen, Jian-Jun; Chi, Ya-Qing; Liang, Bin

    2015-01-01

    As integrated circuits scale down in size, a single high-energy ion strike often affects multiple adjacent logic nodes. The so-called single-event transient (SET) pulse quenching induced by single-event charge sharing collection has been widely studied. In this paper, SET pulse quenching enhancement is found in dummy gate isolated adjacent logic nodes compared with that isolated by the common shallow trench isolation (STI). The physical mechanism is studied in depth and this isolation technique is explored for SET mitigation in combinational standard cells. Three-dimensional (3D) technology computer-aided design simulation (TCAD) results show that this technique can achieve efficient SET mitigation. Project supported by the National Natural Science Foundation of China (Grant No. 61376109) and the Opening Project of National Key Laboratory of Science and Technology on Reliability Physics and Application Technology of Electrical Component, China (Grant No. ZHD201202).

  7. 40 CFR 86.1333 - Transient test cycle generation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...: ER28AP14.006 Where: Max Test Speed = the maximum test speed as calculated in 40 CFR part 1065. (ii) For Otto-cycle engines: ER28AP14.007 Where: Max Test Speed = the maximum test speed as calculated in 40 CFR.... The generation of the maximum torque curve is described in 40 CFR part 1065. (b) Example of...

  8. Single event phenomena: Testing and prediction

    NASA Technical Reports Server (NTRS)

    Kinnison, James D.

    1992-01-01

    Highly integrated microelectronic devices are often used to increase the performance of satellite systems while reducing the system power dissipation, size, and weight. However, these devices are usually more susceptible to radiation than less integrated devices. In particular, the problem of sensitivity to single event upset and latchup is greatly increased as the integration level is increased. Therefore, a method for accurately evaluating the susceptibility of new devices to single event phenomena is critical to qualifying new components for use in space systems. This evaluation includes testing devices for upset or latchup and extrapolating the results of these tests to the orbital environment. Current methods for testing devices for single event effects are reviewed, and methods for upset rate prediction, including a new technique based on Monte Carlo simulation, are presented.

  9. X-33 Injector Ignition Single Cell Test

    NASA Technical Reports Server (NTRS)

    1997-01-01

    The X-33 injector ignition single cell was tested at the Marshall Space Flight Center test stand 116. The X-33 was a sub-scale technology demonstrator prototype of a Reusable Launch Vehicle (RLV) manufactured and named by Lockheed Martin as the Venture Star. The goal of the program was to demonstrate the technologies needed for a full size, single-stage-to-orbit RLV, thus enabling private industry to build and operate the RLV in the first decade of the 21st century. The X-33 program was cancelled in 2001.

  10. Combined single channel and single molecule detection identifies subunit composition of STIM1-activated transient receptor potential canonical (TRPC) channels.

    PubMed

    Asanov, Alexander; Sampieri, Alicia; Moreno, Claudia; Pacheco, Jonathan; Salgado, Alfonso; Sherry, Ryan; Vaca, Luis

    2015-01-01

    Depletion of intracellular calcium ion stores initiates a rapid cascade of events culminating with the activation of the so-called Store-Operated Channels (SOC) at the plasma membrane. Calcium influx via SOC is essential in the initiation of calcium-dependent intracellular signaling and for the refilling of internal calcium stores, ensuring the regeneration of the signaling cascade. In spite of the significance of this evolutionary conserved mechanism, the molecular identity of SOC has been the center of a heated controversy spanning over the last 20 years. Initial studies positioned some members of the transient receptor potential canonical (TRPC) channel superfamily of channels (with the more robust evidence pointing to TRPC1) as a putative SOC. Recent evidence indicates that Stromal Interacting Molecule 1 (STIM1) activates some members from the TRPC family of channels. However, the exact subunit composition of TRPC channels remains undetermined to this date. To identify the subunit composition of STIM1-activated TRPC channels, we developed novel method, which combines single channel electrophysiological measurements based on the patch clamp technique with single molecule fluorescence imaging. We termed this method Single ion Channel Single Molecule Detection technique (SC-SMD). Using SC-SMD method, we have obtained direct evidence of the subunit composition of TRPC channels activated by STIM1. Furthermore, our electrophysiological-imaging SC-SMD method provides evidence at the molecular level of the mechanism by which STIM1 and calmodulin antagonize to modulate TRPC channel activity. PMID:25465892

  11. Total Dose Effects on Single Event Transients in Digital CMOS and Linear Bipolar Circuits

    NASA Technical Reports Server (NTRS)

    Buchner, S.; McMorrow, D.; Sibley, M.; Eaton, P.; Mavis, D.; Dusseau, L.; Roche, N. J-H.; Bernard, M.

    2009-01-01

    This presentation discusses the effects of ionizing radiation on single event transients (SETs) in circuits. The exposure of integrated circuits to ionizing radiation changes electrical parameters. The total ionizing dose effect is observed in both complementary metal-oxide-semiconductor (CMOS) and bipolar circuits. In bipolar circuits, transistors exhibit grain degradation, while in CMOS circuits, transistors exhibit threshold voltage shifts. Changes in electrical parameters can cause changes in single event upset(SEU)/SET rates. Depending on the effect, the rates may increase or decrease. Therefore, measures taken for SEU/SET mitigation might work at the beginning of a mission but not at the end following TID exposure. The effect of TID on SET rates should be considered if SETs cannot be tolerated.

  12. An Investigation of the Ability to Recover from Transients Following Failures for Single-Pilot Rotorcraft

    NASA Technical Reports Server (NTRS)

    Mansur, M. Hossein; Schroeder, Jeffery A.

    1988-01-01

    A moving-base simulation was conducted to investigate a pilot's ability to recover from transients following single-axis hard-over failures of the flight-control system. The investigation was performed in conjunction with a host simulation that examined the influence of control modes on a single pilot's ability to perform various mission elements under high-workload conditions. The NASA Ames large-amplitude-motion Vertical Motion Simulator (VMS) was utilized, and the experimental variables were the failure axis, the severity of the failure, and the airspeed at which the failure occurred. Other factors, such as pilot workload and terrain and obstacle proximity at the time of failure, were kept as constant as possible within the framework of the host simulation task scenarios. No explicit failure warnings were presented to the pilot. Data from the experiment are shown, and pilot ratings are compared with the proposed handling-qualities requirements for military rotorcraft. Results indicate that the current proposed failure transient requirements may need revision.

  13. SINGLE LABORATORY EVALUATION OF PHYTOTOXICITY TEST

    EPA Science Inventory

    The phytotoxicity method is a screening test used to predict the potential impact of chemicals on seed germination and early seedling growth. An evaluation of the procedure was conducted in order to establish the data quality that could be achieved within a single laboratory and ...

  14. 40 CFR 86.1333-2010 - Transient test cycle generation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... engines: ER13JY05.001 Where: MaxTestSpeed = the maximum test speed as calculated in 40 CFR part 1065. (ii... CFR part 1065. (2) Torque is normalized to the maximum torque at the rpm listed with it. Therefore, to.... The generation of the maximum torque curve is described in 40 CFR part 1065. (b) Example of...

  15. 40 CFR 86.1333-2010 - Transient test cycle generation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... engines: ER13JY05.001 Where: MaxTestSpeed = the maximum test speed as calculated in 40 CFR part 1065. (ii... CFR part 1065. (2) Torque is normalized to the maximum torque at the rpm listed with it. Therefore, to.... The generation of the maximum torque curve is described in 40 CFR part 1065. (b) Example of...

  16. 40 CFR 86.1333-2010 - Transient test cycle generation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... engines: ER13JY05.001 Where: MaxTestSpeed = the maximum test speed as calculated in 40 CFR part 1065. (ii... CFR part 1065. (2) Torque is normalized to the maximum torque at the rpm listed with it. Therefore, to.... The generation of the maximum torque curve is described in 40 CFR part 1065. (b) Example of...

  17. 40 CFR 86.1333-2010 - Transient test cycle generation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... engines: ER13JY05.001 Where: MaxTestSpeed = the maximum test speed as calculated in 40 CFR part 1065. (ii... CFR part 1065. (2) Torque is normalized to the maximum torque at the rpm listed with it. Therefore, to.... The generation of the maximum torque curve is described in 40 CFR part 1065. (b) Example of...

  18. NEXT Single String Integration Test Results

    NASA Technical Reports Server (NTRS)

    Soulas, George C.; Patterson, Michael J.; Pinero, Luis; Herman, Daniel A.; Snyder, Steven John

    2010-01-01

    As a critical part of NASA's Evolutionary Xenon Thruster (NEXT) test validation process, a single string integration test was performed on the NEXT ion propulsion system. The objectives of this test were to verify that an integrated system of major NEXT ion propulsion system elements meets project requirements, to demonstrate that the integrated system is functional across the entire power processor and xenon propellant management system input ranges, and to demonstrate to potential users that the NEXT propulsion system is ready for transition to flight. Propulsion system elements included in this system integration test were an engineering model ion thruster, an engineering model propellant management system, an engineering model power processor unit, and a digital control interface unit simulator that acted as a test console. Project requirements that were verified during this system integration test included individual element requirements ; integrated system requirements, and fault handling. This paper will present the results of these tests, which include: integrated ion propulsion system demonstrations of performance, functionality and fault handling; a thruster re-performance acceptance test to establish baseline performance: a risk-reduction PMS-thruster integration test: and propellant management system calibration checks.

  19. Cytosolic calcium transients are a determinant of contraction-induced HSP72 transcription in single skeletal muscle fibers.

    PubMed

    Stary, Creed M; Hogan, Michael C

    2016-05-15

    The intrinsic activating factors that induce transcription of heat shock protein 72 (HSP72) in skeletal muscle following exercise remain unclear. We hypothesized that the cytosolic Ca(2+) transient that occurs with depolarization is a determinant. We utilized intact, single skeletal muscle fibers from Xenopus laevis to test the role of the cytosolic Ca(2+) transient and several other exercise-related factors (fatigue, hypoxia, AMP kinase, and cross-bridge cycling) on the activation of HSP72 transcription. HSP72 and HSP60 mRNA levels were assessed with real-time quantitative PCR; cytosolic Ca(2+) concentration ([Ca(2+)]cyt) was assessed with fura-2. Both fatiguing and nonfatiguing contractions resulted in a significant increase in HSP72 mRNA. As expected, peak [Ca(2+)]cyt remained tightly coupled with peak developed tension in contracting fibers. Pretreatment with N-benzyl-p-toluene sulfonamide (BTS) resulted in depressed peak developed tension with stimulation, while peak [Ca(2+)]cyt remained largely unchanged from control values. Despite excitation-contraction uncoupling, BTS-treated fibers displayed a significant increase in HSP72 mRNA. Treatment of fibers with hypoxia (Po2: <3 mmHg) or AMP kinase activation had no effect on HSP72 mRNA levels. These results suggest that the intermittent cytosolic Ca(2+) transient that occurs with skeletal muscle depolarization provides a sufficient activating stimulus for HSP72 transcription. Metabolic or mechanical factors associated with fatigue development and cross-bridge cycling likely play a more limited role. PMID:26869714

  20. 40 CFR 86.1333-90 - Transient test cycle generation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... test. The torque and rpm feedback signals may be filtered. (d) Idle Speed Enhancement Devices (e.g... feedback torque equal to zero (using, for example, clutch disengagement, speed to torque control switching... longer, the average feedback torque must be within ±10 ft-lbs of zero. To allow for transition, up to...

  1. 40 CFR 86.1333-90 - Transient test cycle generation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... test. The torque and rpm feedback signals may be filtered. (d) Idle Speed Enhancement Devices (e.g... feedback torque equal to zero (using, for example, clutch disengagement, speed to torque control switching... longer, the average feedback torque must be within ±10 ft-lbs of zero. To allow for transition, up to...

  2. Transient thermography testing of unpainted thermal barrier coating surfaces

    NASA Astrophysics Data System (ADS)

    Ptaszek, Grzegorz; Cawley, Peter; Almond, Darryl; Pickering, Simon

    2013-01-01

    This paper has investigated the effects of uneven surface discolouration of a thermal barrier coating (TBC) and of its IR translucency on the thermal responses observed by using mid and long wavelength IR cameras. It has been shown that unpainted blades can be tested satisfactorily by using a more powerful flash heating system and a long wavelength IR camera. The problem of uneven surface emissivity can be overcome by applying 2nd derivative processing of the log-log surface cooling curves.

  3. Transient analysis of single stage GM type double inlet pulse tube cryocooler

    NASA Astrophysics Data System (ADS)

    Gujarati, P. B.; Desai, K. P.; Naik, H. B.; Atrey, M. D.

    2015-12-01

    Transient analysis of single stage GM type double inlet pulse tube cryocooler is carried out using a one dimensional numerical model based on real gas properties of helium. The model solves continuity, momentum and energy equation for gas and solid to analyse the physical process occurring inside of the pulse tube cryocooler. Finite volume method is applied to discretize the governing equations with realistic initial and boundary conditions. Input data required for solving the model are the design data and operating parameters viz. pressure waveform from the compressor, regenerator matrix data, and system geometry including pulse tube, regenerator size and operating frequency for pulse tube cryocooler. The model investigates the effect of orifice opening, double inlet opening, pressure ratio, system geometry on no load temperature and refrigeration power at various temperatures for different charging pressure. The results are compared with experimental data and reasonable agreement is observed. The model can further be extended for designing two stage pulse tube cryocooler.

  4. Nonlocal transient thermal analysis of a single-layered graphene sheet embedded in viscoelastic medium

    NASA Astrophysics Data System (ADS)

    Zenkour, Ashraf M.

    2016-05-01

    The transient thermal analysis of a single-layered graphene sheet (SLGS) embedded in viscoelastic medium is presented by using the nonlocal elasticity theory. The elastic medium, which characterized by the linear Winkler's modulus and Pasternak's (shear) foundation modulus, is changed to a viscoelastic one by including the viscous damping term. The governing dynamical equation is obtained and solved for simply-supported SLGSs. Firstly; the effect of the nonlocal parameter is discussed carefully for the vibration and bending problems. Secondly, the effects of other parameter like aspect ratio, thickness-to-length ratio, Winkler-Pasternak's foundation, viscous damping coefficient on bending field quantities of the SLGSs are investigated in detail. The present results are compared with the corresponding available in the literature. Additional results for thermal local and nonlocal deflections and stresses are presented to investigate the thermal visco-Pasternak's parameters for future comparisons.

  5. Transient getter scheme for the Tokamak Fusion Test Reactor

    SciTech Connect

    Cecchi, J.L.; Cohen, S.A.; Sredniawski, J.J.

    1980-01-01

    The ability of the Tokamak Fusion Test Reactor (TFTR) to attain the largest fusion power gain depends critically on minimizing plasma contamination and controlling the densities of the reacting deuterium and tritium. Experiments on a number of tokamaks have demonstrated that gettering over an appreciable surface area (greater than or equal to 10%) of the vacuum vessel greatly facilitates both of these objectives. One particular problem in implementing a surface pumping system in TFTR, however, is a restriction on the maximum allowable tritium content of the getter. This restriction could require regeneration of the absorbed tritium after as few as 50 machine pulses. We have developed a scheme utilizing SAES Zr/Al getter modules which obviates the need for such frequent interruptions of machine operation by taking advantage of the pulsed operation of TFTR. With the Zr/Al getter at temperatures between 500/sup 0/C to 600/sup 0/C it is possible to achieve a quasi-steady state in the tritium loading where the quantity of tritium desorbed between pulses is equal to the quantity which is absorbed during a pulse. Since frequent thermal cycling is not required, this scheme also reduces the possibility of Zr/Al getter material fatigue.

  6. Electronically controlled mechanical seal for aerospace applications--Part 2: Transient tests

    NASA Technical Reports Server (NTRS)

    Wolff, Paul J.; Salant, Richard F.

    1995-01-01

    An electronically controlled mechanical seal for use as the purge gas seal in a liquid oxygen turbopump has been fabricated and tested under transient operating conditions. The thickness of the lubricating film is controlled by adjusting the coning of the carbon face. This is accomplished by applying a voltage to a piezoelectric actuator to which the carbon face is bonded. The seal has been operated with a closed-loop control system that utilizes either the leakage rate or seal face temperature as the feedback. Both speed and pressure transients have been imposed on the seal. The transient tests have demonstrated that the seal is capable of maintaing low leakage rates while limiting face temperatures.

  7. Transient changes in thyroid functions tests after zoledronic acid infusion.

    PubMed

    Karga, Helen; Giagourta, Irene; Papaioannou, Garyphallia; Katsichti, Paraskevi; Pardalakis, Argyris; Kassi, Georgia; Zagoreou, Apostolia; Triantaphyllopoulou, Maria; Zerva, Cherry

    2011-01-01

    Zoledronic acid (ZA) induces an acute phase response in association with elevation of serum cytokines, which possibly alter the 3 types of iodothyronine deiodinase activity. We therefore studied the possible alteration in thyroid function tests by ZA. We investigated the acute changes in serum thyroid hormones, TSH, cortisol, white blood cells, CRP, interleukin-6 (IL-6) and tumor necrosis factor (TNF-α), before (0) and 1, 2 and 3 days after iv infusion of 5 mg ZA in 24 asymptomatic postmenopausal women with osteoporosis (ZA group) in comparison with a placebo group. In the majority of patients the ZA infusion was associated with acute phase response and fever within 24h after infusion which became attenuated on day three. Concurrently with increase in serum cortisol, CRP, IL-6 and TNF-α, on day 1 and 2, total serum T3 (TT3), free T3 (fT3), total T4 (TT4) and fT4 decreased with a nadir on day 2 in association with an increase in the fT4/fT3 ratio and reverse T3 (rT3) levels. All thyroid function changes returned to the baseline levels on day 3, with cytokines still at higher levels, although lower than those on day 2. Serum TSH remained essentially unchanged throughout the study. The changes in thyroid hormones were at least in part explained by the increased TNF-α, but not by IL-6. ZA induces short term changes in thyroid hormones, characteristic of nonthyroidal illness syndrome (NTIS), in association with an increase in TNF-α and IL-6. PMID:21891972

  8. Single event transient modeling and mitigation techniques for mixed-signal delay locked loop (DLL) and clock circuits

    NASA Astrophysics Data System (ADS)

    Maillard, Pierre

    The purpose of this PhD work has been to investigate, model, test, develop and provide hardening techniques and guidelines for the mitigation of single event transients (SETs) in analog mixed-signal (AMS) delay locked loops (DLLs) for radiation-hardened applications. Delay-locked-loops (DLLs) are circuit substructures that are present in complex ASIC and system-on-a-chip designs. These circuits are widely used in on-chip clock distribution systems to reduce clock skew, to reduce jitter noise, and to recover clock signals at regional points within a global clock distribution system. DLLs are critical to the performance of many clock distribution systems, and in turn, the overall performance of the associated integrated system; as such, complex systems often employ multiple DLLs for clock deskew and distribution tasks. In radiation environments such as on-orbit, these critical circuits represent at-risk points of malfunction for large sections of integrated circuits due to vulnerabilities to radiation-generated transients (i.e. single event transients) that fan out across the system. The analysis of single event effects in analog DLLs has shown that each DLL sub-circuit primitive is vulnerable to single event transients. However, we have identified the voltage controlled delay line (VCDL) sub-circuit as the most sensitive to radiation-induced single event effects generating missing clock pulses that increase with the operating frequency of the circuit. This vulnerability increases with multiple instantiation of DLLs as clock distribution nodes throughout an integrated system on a chip. To our knowledge, no complete work in the rad-hard community regarding the hardening of mixed-signal DLLs against single event effects (missing pulses) has been developed. Most of the work present in the literature applies the "brute force" and well-established digital technique of triple modular redundancy (TMR) to the digital subcomponents. We have developed two novel design techniques for the mitigation of DLL missing pulses that are fully implementable in modern CMOS technologies. These techniques offer to the community the choice of hardening using a restoring current technique in the VCDL sub-circuit to inhibit the creation of missing pulse errors, or using a combinational logic error monitoring technique to correct missing pulses after they occur in real time. We have implemented both of these techniques with minimal area and power penalties when compared to TMR. In addition, these hardening techniques have been extrapolated to other clock circuits, such as digital PLLs. The first hardening technique uses a hardened complementary differential pair VCDL to increase the critical charge (Qcrit) necessary for single event transient generation and thus mitigate missing pulses at the source. Our implementation of this technique at 180 nm, 90 nm and 40 nm required less than a 2% area penalty over a non-hardened design. To experimentally validate this technique, hardened VCDLs were designed and fabricated in 180-nm IBM and 40-nm UMC technologies, then tested at the Naval Research Lab in Washington D.C. The second hardening technique, based on combinational logic pulse monitoring, uses an error correction circuit to mitigate the missing pulses as they occur. This ECC technique is implemented via a "peeled" VCDL (i.e. each transistor is split in area but doubled in multiplicity). We have shown the effectiveness of this technique by implementing it in a Xilinx Virtex 5 FPGA. Furthermore, this new ECC technique is independent of technology scaling -- a highly valuable attribute for sub-50 nm design applications. In addition to the formulation, simulation, prototyping, fabrication, and testing of these new hardening solutions, we developed a unique single event analytical model to guide future hardened DLL designs at advanced technology nodes. The model was furthermore generalized to PLL and DLLs. These analytical models were then used to provide a set of equations to the designer for important insight into hardening choices and tradeoffs based on design specifications, in conjunction with a broad set of guidelines for the design of hardened DLLs regarding circuit topology choices and parameter sensitivity on radiation exposure. We are confident that these results, tools, and guidelines will significantly expand the state-of-the-art in the design of hardened DLL clocking circuits for rad-hard applications.

  9. Transient Mitochondrial Depolarizations Reflect Focal Sarcoplasmic Reticular Calcium Release in Single Rat Cardiomyocytes

    PubMed Central

    Duchen, Michael R.; Leyssens, Anne; Crompton, Martin

    1998-01-01

    Digital imaging of mitochondrial potential in single rat cardiomyocytes revealed transient depolarizations of mitochondria discretely localized within the cell, a phenomenon that we shall call “flicker.” These events were usually highly localized and could be restricted to single mitochondria, but they could also be more widely distributed within the cell. Contractile waves, either spontaneous or in response to depolarization with 50 mM K+, were associated with propagating waves of mitochondrial depolarization, suggesting that propagating calcium waves are associated with mitochondrial calcium uptake and consequent depolarization. Here we demonstrate that the mitochondrial flicker was directly related to the focal release of calcium from sarcoplasmic reticular (SR) calcium stores and consequent uptake of calcium by local mitochondria. Thus, the events were dramatically reduced by (a) depletion of SR calcium stores after long-term incubation in EGTA or thapsigargin (500 nM); (b) buffering intracellular calcium using BAPTA-AM loading; (c) blockade of SR calcium release with ryanodine (30 μM); and (d) blockade of mitochondrial calcium uptake by microinjection of diaminopentane pentammine cobalt (DAPPAC), a novel inhibitor of the mitochondrial calcium uniporter. These observations demonstrate that focal SR calcium release results in calcium microdomains sufficient to promote local mitochondrial calcium uptake, suggesting a tight coupling of calcium signaling between SR release sites and nearby mitochondria. PMID:9722610

  10. Transient Testing of Nuclear Fuels and Materials in the United States

    NASA Astrophysics Data System (ADS)

    Wachs, Daniel M.

    2012-12-01

    The United States has established that transient irradiation testing is needed to support advanced light water reactors fuel development. The U.S. Department of Energy (DOE) has initiated an effort to reestablish this capability. Restart of the Transient Testing Reactor (TREAT) facility located at the Idaho National Laboratory (INL) is being considered for this purpose. This effort would also include the development of specialized test vehicles to support stagnant capsule and flowing loop tests as well as the enhancement of postirradiation examination capabilities and remote device assembly capabilities at the Hot Fuel Examination Facility. It is anticipated that the capability will be available to support testing by 2018, as required to meet the DOE goals for the development of accident-tolerant LWR fuel designs.

  11. Total Dose Effects on Single Event Transients in Linear Bipolar Systems

    NASA Technical Reports Server (NTRS)

    Buchner, Stephen; McMorrow, Dale; Bernard, Muriel; Roche, Nicholas; Dusseau, Laurent

    2008-01-01

    Single Event Transients (SETs) originating in linear bipolar integrated circuits are known to undermine the reliability of electronic systems operating in the radiation environment of space. Ionizing particle radiation produces a variety of SETs in linear bipolar circuits. The extent to which these SETs threaten system reliability depends on both their shapes (amplitude and width) and their threshold energies. In general, SETs with large amplitudes and widths are the most likely to propagate from a bipolar circuit's output through a subsystem. The danger these SET pose is that, if they become latched in a follow-on circuit, they could cause an erroneous system response. Long-term exposure of linear bipolar circuits to particle radiation produces total ionizing dose (TID) and/or displacement damage dose (DDD) effects that are characterized by a gradual degradation in some of the circuit's electrical parameters. For example, an operational amplifier's gain-bandwidth product is reduced by exposure to ionizing radiation, and it is this reduction that contributes to the distortion of the SET shapes. In this paper, we compare SETs produced in a pristine LM124 operational amplifier with those produced in one exposed to ionizing radiation for three different operating configurations - voltage follower (VF), inverter with gain (IWG), and non-inverter with gain (NIWG). Each configuration produces a unique set of transient shapes that change following exposure to ionizing radiation. An important finding is that the changes depend on operating configuration; some SETs decrease in amplitude, some remain relatively unchanged, some become narrower and some become broader.

  12. A study of the transient performance of hydrostatic journal bearings. I - Test apparatus and facility

    NASA Astrophysics Data System (ADS)

    Scharrer, J. K.; Tellier, J.; Hibbs, R.

    1992-10-01

    A test apparatus was developed for studies of the transient performance of hydrostatic journal bearings operating in liquid nitrogen. The data obtained give the number of revolutions of the shaft contact before the liftoff and after touchdown as a function of bearing/shaft material combinations and operating conditions.

  13. 40 CFR Appendix E to Subpart S of... - Transient Test Driving Cycle

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 2 2013-07-01 2013-07-01 false Transient Test Driving Cycle E Appendix E to Subpart S of Part 51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS REQUIREMENTS FOR PREPARATION, ADOPTION, AND SUBMITTAL OF IMPLEMENTATION PLANS Inspection/Maintenance Program Requirements Pt. 51, Subpt....

  14. Testing and Lubrication for Single Race Bearings

    SciTech Connect

    Steinhoff, R.G.

    1998-03-04

    Three ES and H-compatible lubricants (Environment, Safety and Health) for single race bearing applications and one hybrid-material single race bearings were evaluated and compared against single race bearings with trichlorotrifluoroethane (Freon) deposition of low molecular weight polytetrafluoroethylene (PTFE) bearing lubricant extracted from Vydax{trademark}. Vydax is a product manufactured by DuPont consisting of various molecular weights of PTFE suspended in trichlorotrifluoroethane (Freon), which is an ozone-depleting solvent. Vydax has been used as a bearing lubricant in stronglink mechanisms since 1974. Hybrid bearings with silicon nitride balls and molded glass-nylon-Teflon retainers, bearings lubricated with titanium carbide (TiC) on the balls, bearings lubricated with sputtered MoS{sub 2} on races and retainers, and bearings lubricated with electrophoretically deposited MoS{sub 2} were evaluated. The bearings were maintained in a preloaded state in bearing cartridges during cycling and vibration tests. Bearings with electrophoretically deposited MoS{sub 2} performed as well as bearings lubricated with Vydax and were the best performing candidate. All candidates were suitable for low preload applications. Bearings with TiC coated balls and bearings lubricated with sputtered MoS{sub 2} on the races and retainers performed well at high preloads, though not as well as bearings lubricated with electrophoretic deposition of MoS{sub 2}. Bearings with silicon nitride balls were not suitable for high preload applications.

  15. Method of Generating Transient Equivalent Sink and Test Target Temperatures for Swift BAT

    NASA Technical Reports Server (NTRS)

    Choi, Michael K.

    2004-01-01

    The NASA Swift mission has a 600-km altitude and a 22 degrees maximum inclination. The sun angle varies from 45 degrees to 180 degrees in normal operation. As a result, environmental heat fluxes absorbed by the Burst Alert Telescope (BAT) radiator and loop heat pipe (LHP) compensation chambers (CCs) vary transiently. Therefore the equivalent sink temperatures for the radiator and CCs varies transiently. In thermal performance verification testing in vacuum, the radiator and CCs radiated heat to sink targets. This paper presents an analytical technique for generating orbit transient equivalent sink temperatures and a technique for generating transient sink target temperatures for the radiator and LHP CCs. Using these techniques, transient target temperatures for the radiator and LHP CCs were generated for three thermal environmental cases: worst hot case, worst cold case, and cooldown and warmup between worst hot case in sunlight and worst cold case in the eclipse, and three different heat transport values: 128 W, 255 W, and 382 W. The 128 W case assumed that the two LHPs transport 255 W equally to the radiator. The 255 W case assumed that one LHP fails so that the remaining LHP transports all the waste heat from the detector array to the radiator. The 382 W case assumed that one LHP fails so that the remaining LHP transports all the waste heat from the detector array to the radiator, and has a 50% design margin. All these transient target temperatures were successfully implemented in the engineering test unit (ETU) LHP and flight LHP thermal performance verification tests in vacuum.

  16. Single cycle and transient force measurements in dynamic atomic force microscopy.

    PubMed

    Gadelrab, Karim; Santos, Sergio; Font, Josep; Chiesa, Matteo

    2013-11-21

    The monitoring of the deflection of a micro-cantilever, as the end of a sharp probe mounted at its end, i.e. the tip, interacts with a surface, forms the foundation of atomic force microscopy AFM. In a nutshell, developments in the field are driven by the requirement of obtaining ever increasing throughput and sensitivity, and enhancing the versatility of the instrument to simultaneously map the topography and quantify nanoscale processes and properties. In the most common dynamic mode of operation, the motion of the driven cantilever is monitored at a single point on its longitudinal axis. Here, we show that from this single point a waveform is obtained that contains all the details about conservative and dissipative interactions. Then a formalism that accounts for multiple arbitrary flexural modes is developed for an indirectly driven cantilever. The formalism is shown to allow recovery of the details of the interaction even in the presence of complex and relevant hysteretic forces when the cantilever oscillates in the steady state. In a different approach, we develop a formalism that monitors the wave profile of the cantilever, i.e. the waveform at five different points on its longitudinal axis. With this formalism the interaction can be reconstructed during a single oscillation cycle even in the transient state of oscillation. Finally, we discuss the potential and advantages of the proposed methods and future technical challenges. Other standard and state of the art techniques and methods are also discussed and compared with the ones presented here. This work should also provide insight into the current high throughput-high sensitivity developments dealing with multifrequency dynamic AFM where information is recovered from multiple eigenmodes. PMID:24071898

  17. History-dependent excitability as a single-cell substrate of transient memory for information discrimination.

    PubMed

    Baroni, Fabiano; Torres, Joaquín J; Varona, Pablo

    2010-01-01

    Neurons react differently to incoming stimuli depending upon their previous history of stimulation. This property can be considered as a single-cell substrate for transient memory, or context-dependent information processing: depending upon the current context that the neuron "sees" through the subset of the network impinging on it in the immediate past, the same synaptic event can evoke a postsynaptic spike or just a subthreshold depolarization. We propose a formal definition of History-Dependent Excitability (HDE) as a measure of the propensity to firing in any moment in time, linking the subthreshold history-dependent dynamics with spike generation. This definition allows the quantitative assessment of the intrinsic memory for different single-neuron dynamics and input statistics. We illustrate the concept of HDE by considering two general dynamical mechanisms: the passive behavior of an Integrate and Fire (IF) neuron, and the inductive behavior of a Generalized Integrate and Fire (GIF) neuron with subthreshold damped oscillations. This framework allows us to characterize the sensitivity of different model neurons to the detailed temporal structure of incoming stimuli. While a neuron with intrinsic oscillations discriminates equally well between input trains with the same or different frequency, a passive neuron discriminates better between inputs with different frequencies. This suggests that passive neurons are better suited to rate-based computation, while neurons with subthreshold oscillations are advantageous in a temporal coding scheme. We also address the influence of intrinsic properties in single-cell processing as a function of input statistics, and show that intrinsic oscillations enhance discrimination sensitivity at high input rates. Finally, we discuss how the recognition of these cell-specific discrimination properties might further our understanding of neuronal network computations and their relationships to the distribution and functional connectivity of different neuronal types. PMID:21203387

  18. History-Dependent Excitability as a Single-Cell Substrate of Transient Memory for Information Discrimination

    PubMed Central

    Baroni, Fabiano; Torres, Joaquín J.; Varona, Pablo

    2010-01-01

    Neurons react differently to incoming stimuli depending upon their previous history of stimulation. This property can be considered as a single-cell substrate for transient memory, or context-dependent information processing: depending upon the current context that the neuron “sees” through the subset of the network impinging on it in the immediate past, the same synaptic event can evoke a postsynaptic spike or just a subthreshold depolarization. We propose a formal definition of History-Dependent Excitability (HDE) as a measure of the propensity to firing in any moment in time, linking the subthreshold history-dependent dynamics with spike generation. This definition allows the quantitative assessment of the intrinsic memory for different single-neuron dynamics and input statistics. We illustrate the concept of HDE by considering two general dynamical mechanisms: the passive behavior of an Integrate and Fire (IF) neuron, and the inductive behavior of a Generalized Integrate and Fire (GIF) neuron with subthreshold damped oscillations. This framework allows us to characterize the sensitivity of different model neurons to the detailed temporal structure of incoming stimuli. While a neuron with intrinsic oscillations discriminates equally well between input trains with the same or different frequency, a passive neuron discriminates better between inputs with different frequencies. This suggests that passive neurons are better suited to rate-based computation, while neurons with subthreshold oscillations are advantageous in a temporal coding scheme. We also address the influence of intrinsic properties in single-cell processing as a function of input statistics, and show that intrinsic oscillations enhance discrimination sensitivity at high input rates. Finally, we discuss how the recognition of these cell-specific discrimination properties might further our understanding of neuronal network computations and their relationships to the distribution and functional connectivity of different neuronal types. PMID:21203387

  19. PHASE I SINGLE CELL ELECTROLYZER TEST RESULTS

    SciTech Connect

    Steimke, J; Timothy Steeper, T

    2008-08-05

    This document reports the results of Phase I Single Cell testing of an SO{sub 2}-Depolarized Water Electrolyzer. Testing was performed primarily during the first quarter of FY 2008 at the Savannah River National Laboratory (SRNL) using an electrolyzer cell designed and built at SRNL. Other facility hardware were also designed and built at SRNL. This test further advances this technology for which work began at SRNL in 2005. This research is valuable in achieving the ultimate goal of an economical hydrogen production process based on the Hybrid Sulfur (HyS) Cycle. The focus of this work was to conduct single cell electrolyzer tests to further develop the technology of SO{sub 2}-depolarized electrolysis as part of the HyS Cycle. The HyS Cycle is a hybrid thermochemical cycle that may be used in conjunction with advanced nuclear reactors or centralized solar receivers to produce hydrogen by water-splitting. Like all other sulfur-based cycles, HyS utilizes the high temperature thermal decomposition of sulfuric acid to produce oxygen and regenerate sulfur dioxide. The unique aspect of HyS is the generation of hydrogen in a water electrolyzer that is operated under conditions where dissolved sulfur dioxide depolarizes the anodic reaction, resulting in substantial voltage reduction. Low cell voltage is essential for both thermodynamic efficiency and hydrogen cost. Sulfur dioxide is oxidized at the anode, producing sulfuric acid that is sent to the high temperature acid decomposition portion of the cycle. The electrolyzer cell uses the membrane electrode assembly (MEA) concept. The anode and cathode are formed by spraying platinum containing catalyst on both sides of a Proton Exchange Membrane (PEM). In most testing the material of the PEM was NafionR. The electrolyzer cell active area can be as large as 54.8 cm{sup 2}. Feed to the anode of the electrolyzer is a sulfuric acid solution containing sulfur dioxide. The partial pressure of sulfur dioxide could be varied in the range of 1 to 6 atm (15 to 90 psia). Temperatures could be controlled in the range from ambient to 80 C. Hydrogen generated at the cathode of the cell was collected for the purpose of flow measurement and composition analysis. The test facility proved to be easy to operate, versatile, and reliable.

  20. Transient oxidative stress and inflammation after intraperitoneal administration of multiwalled carbon nanotubes functionalized with single strand DNA in rats

    SciTech Connect

    Clichici, Simona; Biris, Alexandru Radu; Tabaran, Flaviu; Filip, Adriana

    2012-03-15

    Multi-walled carbon nanotubes (MWCNTs) are widely used for nanotechnology. Their impact on living organisms is, however, not entirely clarified. Oxidative stress and inflammation seem to be the key mechanisms involved in MWCNTs' cytotoxicity. Until present, pulmonary and skin models were the main tested experimental designs to assess carbon nanotubes' toxicity. The systemic administration of MWCNTs is essential, with respect for future medical applications. Our research is performed on Wistar rats and is focused on the dynamics of oxidative stress parameters in blood and liver and pro-inflammatory cytokines in liver, after single dose (270 mg l{sup −1}) ip administration of MWCNTs (exterior diameter 15–25 nm, interior diameter 10–15 nm, surface 88 m{sup 2} g{sup −1}) functionalized with single strand DNA (ss-DNA). The presence of MWCNTs in blood was assessed by Raman spectroscopy, while in liver histological examination and confocal microscopy were used. It was found that ss-DNA-MWCNTs induce oxidative stress in plasma and liver, with the return of the tested parameters to normal values, 6 h after ip injection of nanotubes, with the exception of reduced glutathione in plasma. The inflammatory cytokines (TNF-α, IL-1β) had a similar pattern of evolution. We also assessed the level of ERK1/2 and the phosphorylation of p65 subunit of NF-kB in liver that had a transient increase and returned to normal at the end of the tested period. Our results demonstrate that ss-DNA-MWCNTs produce oxidative stress and inflammation, but with a transient pattern. Given the fact that antioxidants modify the profile not only for oxidative stress, but also of inflammation, the dynamics of these alterations may be of practical importance for future protective strategies. -- Highlights: ► ss-DNA-MWCNTs ip administration induce oxidative stress in plasma and liver. ► ss-DNA-MWCNTs ip administration determine liver inflammation. ► ERK1/2 and p65 phosphorylated NF-KB increase in liver after MWCNTs ip injection. ► All the alterations, except plasma GSH, return to normal within 6 days.

  1. The transient oxidation of single crystal NiAl+Zr. M.S. Thesis. Final Report

    NASA Technical Reports Server (NTRS)

    Doychak, J. K.

    1983-01-01

    The 800 C oxidation of oriented single crystals of Zr doped beta-NiAl was studied using transmission electron microscopy. The oxide phases and metal-oxide orientation relationships were determined to characterize the transient stages of oxidation prior to the transformation to or formation of alpha-Al2O3. On (001) and (012) metal orientations, NiAl2O4 was the first oxide to form followed by delta-Al2O3 which becomes the predominant oxide phase. All oxides were highly epitaxially related to the metal; the orientation relationships being function of parallel cation close-packed directions in the meta and oxide. On (011) and (111) metal orientations, gamma-Al2O3 became the predominant oxide phase rather than delta-Al2O3, indicating a structural stability from the highly epitaxial oxides. The relative concentration of aluminum in the oxide scales increased with time indicating preferential gamma-or delta-Al2O3 growth. The striking feature common to the orientation relationships is the alignment of 100 m and 110 ox directions, believed to result from the minimal 3 percent mismatch between the corresponding (100)m and (110)ox planes.

  2. Line-edge roughness induced single event transient variation in SOI FinFETs

    NASA Astrophysics Data System (ADS)

    Weikang, Wu; Xia, An; Xiaobo, Jiang; Yehua, Chen; Jingjing, Liu; Xing, Zhang; Ru, Huang

    2015-11-01

    The impact of process induced variation on the response of SOI FinFET to heavy ion irradiation is studied through 3-D TCAD simulation for the first time. When FinFET biased at OFF state configuration (Vgs = 0, Vds = Vdd) is struck by a heavy ion, the drain collects ionizing charges under the electric field and a current pulse (single event transient, SET) is consequently formed. The results reveal that with the presence of line-edge roughness (LER), which is one of the major variation sources in nano-scale FinFETs, the device-to-device variation in terms of SET is observed. In this study, three types of LER are considered: type A has symmetric fin edges, type B has irrelevant fin edges and type C has parallel fin edges. The results show that type A devices have the largest SET variation while type C devices have the smallest variation. Further, the impact of the two main LER parameters, correlation length and root mean square amplitude, on SET variation is discussed as well. The results indicate that variation may be a concern in radiation effects with the down scaling of feature size.

  3. Numerical simulation and experimental study of transient liquid phase bonding of single crystal superalloys

    NASA Astrophysics Data System (ADS)

    Ghoneim, Adam

    The primary goals of the research in this dissertation are to perform a systematic study to identify and understand the fundamental cause of prolonged processing time during transient liquid phase bonding of difficult-to-bond single crystal Ni-base materials, and use the acquired knowledge to develop an effective way to reduce the isothermal solidification time without sacrificing the single crystalline nature of the base materials. To achieve these objectives, a multi-scale numerical modeling approach, that involves the use of a 2-D fully implicit moving-mesh Finite Element method and a Cellular Automata method, was developed to theoretically investigate the cause of long isothermal solidification times and determine a viable way to minimize the problem. Subsequently, the predictions of the theoretical models are experimentally validated. Contrary to previous suggestions, numerical calculations and experimental verifications have shown that enhanced intergranular diffusivity has a negligible effect on solidification time in cast superalloys and that another important factor must be responsible. In addition, it was found that the concept of competition between solute diffusivity and solubility as predicted by standard analytical TLP bonding models and reported in the literature as a possible cause of long solidification times is not suitable to explain salient experimental observations. In contrast, however, this study shows that the problem of long solidification times, which anomalously increase with temperature is fundamentally caused by departure from diffusion controlled parabolic migration of the liquid-solid interface with holding time during bonding due to a significant reduction in the solute concentration gradient in the base material. Theoretical analyses showed it is possible to minimize the solidification time and prevent formation of stray-grains in joints between single crystal substrates by using a composite powder mixture of brazing alloy and base alloy as the interlayer material, which prior to the present work has been reported to be unsuitable. This was experimentally verified and the use of the composite powder mixture as interlayer material to reduce the solidification time and avoid stray-grain formation during TLP bonding of single crystal superalloys has been reported for the first time in this research.

  4. Pressure transient tests on geothermal wells in the Dogger aquifer, Paris Basin

    NASA Astrophysics Data System (ADS)

    giuglaris, elodie; hamm, virginie

    2014-05-01

    In this work, we propose a new interpretation of pressure transient tests conducted in more than sixty wells targeting the Dogger formation in the Paris basin. The most part of these wells were drilled during the eighties over a very short period of time in an urban area. The transient tests were only recorded during a pressure buildup and show that contrary to what has long been assumed the Dogger aquifer behavior is not homogeneous. The interpretation of the obtained data was mainly done with Horner's method, independently for each well, and assuming generally that the aquifer is homogeneous. Available data from pressure transient tests are limited because of the precision of the tools used, and because pressure buildup was only recorded during eight to twelve hours. The objective was to determine the average transmissivity and the skin factor in order to obtain the productivity of the wells. We gather all available data, including those obtained on the thirteen recent wells, and propose a new interpretation in terms of aquifer model. We use the pressure derivative method developed in the nineties for oil reservoirs which allows a better visualization of the model and of the heterogeneity of the aquifer. Most of the well tests have a derivative pressure curve with a slope equal to zero, that does not change after the well bore effects, confirming that the aquifer is relatively homogenous. However on a dozen of wells, data from pressure transient tests display singular behaviors that can be related to a double porosity or double permeability model for some wells and to a composite model for others. These observations question the validity of a homogeneous model for the Dogger aquifer in the Paris basin and the currently used parameters for the thermal and hydrodynamic predictive model of geothermal exploitation. Finally, this work increases our understanding of the Dogger aquifer in the Paris basin and will allow the optimization of the ongoing hydraulic tests and the future exploitation of geothermal energy in the area.

  5. Quantifying Transient 3D Dynamical Phenomena of Single mRNA Particles in Live Yeast Cell Measurements

    PubMed Central

    Calderon, Christopher P.; Thompson, Michael A.; Casolari, Jason M.; Paffenroth, Randy C.; Moerner, W. E.

    2013-01-01

    Single-particle tracking (SPT) has been extensively used to obtain information about diffusion and directed motion in a wide range of biological applications. Recently, new methods have appeared for obtaining precise (10s of nm) spatial information in three dimensions (3D) with high temporal resolution (measurements obtained every 4ms), which promise to more accurately sense the true dynamical behavior in the natural 3D cellular environment. Despite the quantitative 3D tracking information, the range of mathematical methods for extracting information about the underlying system has been limited mostly to mean-squared displacement analysis and other techniques not accounting for complex 3D kinetic interactions. There is a great need for new analysis tools aiming to more fully extract the biological information content from in vivo SPT measurements. High-resolution SPT experimental data has enormous potential to objectively scrutinize various proposed mechanistic schemes arising from theoretical biophysics and cell biology. At the same time, methods for rigorously checking the statistical consistency of both model assumptions and estimated parameters against observed experimental data (i.e. goodness-of-fit tests) have not received great attention. We demonstrate methods enabling (1) estimation of the parameters of 3D stochastic differential equation (SDE) models of the underlying dynamics given only one trajectory; and (2) construction of hypothesis tests checking the consistency of the fitted model with the observed trajectory so that extracted parameters are not over-interpreted (the tools are applicable to linear or nonlinear SDEs calibrated from non-stationary time series data). The approach is demonstrated on high-resolution 3D trajectories of single ARG3 mRNA particles in yeast cells in order to show the power of the methods in detecting signatures of transient directed transport. The methods presented are generally relevant to a wide variety of 2D and 3D SPT tracking applications. PMID:24015725

  6. Full-scale controlled transient heat-transfer tests data-analysis report

    NASA Astrophysics Data System (ADS)

    McIntyre, B. A.; Volpenhein, E. C.

    1982-08-01

    Transient critical heat flux (CHF) behavior was studied under conditions typical of those calculated to occur in the first few seconds following a postulated large break loss of coolant accident (LOCA) in a pressurized water reactor (PWR). The axial power profile was a chopped cosine with a 1.66 peak to average power ratio. The primary focus was to obtain a data base, for transient CHF in a rod bundle cooled by water, amenable to model development efforts. A single controlled parameter variation approach was utilized. The parameters variation included pressure, pressure decay rate, flow, flow decay rate, flow direction, power, inlet temperature, and initial system pressure. These parameters are selected to bound the values which are calculated to occur during a large break PWR LOCA.

  7. Single-event-transient effects in sub-70 nm bulk and SOI FinFETs

    NASA Astrophysics Data System (ADS)

    El Mamouni, Farah

    After fourteen years of research and investigations by engineers in the university and industry communities, FinFET devices are finally ready to use in products [1-2]. FinFET technologies have been demonstrated to outperform planar technologies for high speed, low power and high performance applications, while maintaining the shrinking trends of microelectronics (beyond 32 nm) for at least the next two to three technology generations. These promising findings were enough for leading chip manufacturers like Intel to announce their plans to mass-produce FinFETs in the near future [3-4]. However, the device response in extreme environments (i.e., space) is still not well understood. Exploring the behavior of FinFETs in such environments is also important for the aerospace and medical industries, where unhardened commercial off the shelf (COTS) electronics are used. The objective of this work is to explore the transient electrical behavior of FinFET devices in both bulk and SOI technologies in radiation-rich environments through laser and heavy ion testing. A further objective of this work is to contribute to improving the performance of FinFET devices, in particular in harsh environments. Indeed, the new results obtained in this work identify the physical regions in the devices that are most sensitive to radiation effects and how they affect the radiation response. The findings will help engineers to design new generations of FinFET devices with higher tolerance to radiation effects.

  8. Compilation of Quality Assurance Documentation for Analyses Performed for the Resumption of Transient Testing Environmental Assessment

    SciTech Connect

    Annette L. Schafer; A. Jeffrey Sondrup

    2013-11-01

    This is a companion document to the analyses performed in support of the environmental assessment for the Resumption of Transient Fuels and Materials Testing. It is provided to allow transparency of the supporting calculations. It provides computer code input and output. The basis for the calculations is documented separately in INL (2013) and is referenced, as appropriate. Spreadsheets used to manipulate the code output are not provided.

  9. An infrastructure for accurate characterization of single-event transients in digital circuits☆

    PubMed Central

    Savulimedu Veeravalli, Varadan; Polzer, Thomas; Schmid, Ulrich; Steininger, Andreas; Hofbauer, Michael; Schweiger, Kurt; Dietrich, Horst; Schneider-Hornstein, Kerstin; Zimmermann, Horst; Voss, Kay-Obbe; Merk, Bruno; Hajek, Michael

    2013-01-01

    We present the architecture and a detailed pre-fabrication analysis of a digital measurement ASIC facilitating long-term irradiation experiments of basic asynchronous circuits, which also demonstrates the suitability of the general approach for obtaining accurate radiation failure models developed in our FATAL project. Our ASIC design combines radiation targets like Muller C-elements and elastic pipelines as well as standard combinational gates and flip-flops with an elaborate on-chip measurement infrastructure. Major architectural challenges result from the fact that the latter must operate reliably under the same radiation conditions the target circuits are exposed to, without wasting precious die area for a rad-hard design. A measurement architecture based on multiple non-rad-hard counters is used, which we show to be resilient against double faults, as well as many triple and even higher-multiplicity faults. The design evaluation is done by means of comprehensive fault injection experiments, which are based on detailed Spice models of the target circuits in conjunction with a standard double-exponential current injection model for single-event transients (SET). To be as accurate as possible, the parameters of this current model have been aligned with results obtained from 3D device simulation models, which have in turn been validated and calibrated using micro-beam radiation experiments at the GSI in Darmstadt, Germany. For the latter, target circuits instrumented with high-speed sense amplifiers have been used for analog SET recording. Together with a probabilistic analysis of the sustainable particle flow rates, based on a detailed area analysis and experimental cross-section data, we can conclude that the proposed architecture will indeed sustain significant target hit rates, without exceeding the resilience bound of the measurement infrastructure. PMID:24748694

  10. Effect of Holding Time on Microstructure and Properties of Transient Liquid-Phase-Bonded Joints of a Single Crystal Alloy

    NASA Astrophysics Data System (ADS)

    Chai, Lu; Huang, Jihua; Hou, Jinbao; Lang, Bo; Wang, Li

    2015-06-01

    Experimental investigations have been done to verify the effects of hold time during transient liquid-phase bonding on joint microstructure and mechanical properties of a nickel-based single crystal superalloy. The superalloy was bonded at 1473-1513 K for 0.25-12 h in vacuum environment. A set of parameters, 1513 K for 10 h, was determined as the optimum bonding condition. SEM results revealed that the joint without the completion of isothermal solidification is comprised of four different distinct regions, namely, rapid solidification zone (RSZ), isothermal solidification zone (ISZ), diffusion zone, and base metal. EBSD data indicated that the ISZ across the centerline of the bond has an undifferentiated crystallographic orientation being the same as the base metal. At increasing hold times at 1513 K, RSZ and also borides would disappear and result in an improvement of mechanical properties. Mechanical property tests at elevated temperatures have been done to determine the joints' quality. High-temperature creep rupture strength (for 100 h at 1373 K) and tensile strength (at 1273 K) of the joints could both attain 90% of those of the base metal.

  11. Testing and analysis of structural integrity of electrosleeved tubes under severe accident transients

    SciTech Connect

    Majumdar, S.

    1999-12-10

    The structural integrity of flawed steam generator tubing with Electrosleeves{trademark} under simulated severe accident transients was analyzed by analytical models that used available material properties data and results from high-temperature tests conducted on Electrosleeved tubes. The Electrosleeve material is almost pure Ni and derives its strength and other useful properties from its nanocrystalline microstructure, which is stable at reactor operating temperatures. However, it undergoes rapid grain growth, at the high temperatures expected during severe accidents, resulting in a loss of strength and a corresponding decrease in flow stress. The magnitude of this decrease depends on the time-temperature history during the accident. Failure tests were conducted at ANL and FTI on internally pressurized Electrosleeved tubes with 80% and 100% throughwall machined axial notches in tie parent tubes that were subjected to simulated severe accident temperature transients. The test results, together with the analytical model, were used to estimate the unaged flow stress curve of the Electrosleeved material at high temperatures. Failure temperatures for Electrosleeved tubes with throughwall and part-throughwall axial cracks of various lengths in the parent tubes were calculated for a postulated severe accident transient.

  12. Transient Pressure Test Article (TPTA) 1.1 and 1.1A, volume 1

    NASA Technical Reports Server (NTRS)

    Rebells, Clarence A.

    1988-01-01

    This final test report presents the results obtained during the static hot firing and cold-gas high Q tests of the first Transient Pressure Test Article (TPTA) 1.1. The TPTA consisted of field test joints A and B, which were the original RSRM J-insulation configuration, with a metal capture feature. It also consisted of a flight configuration nozzle-to-case test joint (Joint D) with shorter vent slots. Fluorocarbon O-rings were used in all the test joints. The purpose of the TPTA tests is to evaluate and characterize the RSMR field and nozzle-to-case joints under the influence of ignition and strut loads during liftoff anf high Q. All objectives of the cold-gas high Q (TPTA 1.1A) test were met and all measurements were close to predicted values. During the static hot-firing test (TPTA 1.1), the motor was inadvertently plugged by the quench injector plug, making it a more severe test, although no strut loads were applied. The motor was depressurized after approximately 11 min using an auxiliary system, and no anomalies were noted. In the static hot-firing test, pressure was incident on the insulation and the test joint gaps were within the predicted range. During the static hot-firing test, no strut loads were applied because the loading system malfunctioned. For this test, all measurements were within range of similar tests performed without strut loads.

  13. Nonlinear transient wave excitation as a new tool in model testing

    SciTech Connect

    Clauss, G.F.; Kuehnlein, W.L.

    1996-12-31

    Short extension transient waves with tailor-made spectra are extremely efficient for model testing. For small water elevations a linear description of the wave field is satisfactory. With higher transient wave trains, however, the linear description becomes increasingly inaccurate, and a new numerical technique must be developed. Such a new method is based on the fact that short and high wave groups with strong nonlinear characteristics evolve from long and low wave groups, which are characterized by linear principles. As the total energy of the transient wave is invariant during its metamorphosis, the initial linear Fourier spectrum is selected as the backbone of wave information or as the primordial cell from which all nonlinearities are hatched. Based on the initial Fourier spectrum which is the core of the wave information operator the shape variation of the linear transient wave train during propagation is calculated. At selected positions the nonlinear expansion is accomplished by solving the mutually dependent particle motion equations in time domain. The proposed new method uses a numerical nonlinear description of transient wave trains as a function of time or space for any fixed or moving reference point. At its primordial state it is based on a linear superposition of wave information which is complemented by an expanded velocity potential to calculate nonlinear surface elevations, particle motions, velocities, and accelerations. After the nonlinear wave trains converge and pass the concentration point only to diverge and fade away as long, low and linear wave groups, the primordial linear Fourier spectrum can be found again at the end of the development. This step can be used to monitor the transformation. Wave energy spectra and the shape of the wave train can be designed with special regard to the proposed task. Based on these data the entire wave field can be determined.

  14. Testing the ontogenetic base for the transient model of inflorescence development

    PubMed Central

    Bull-Hereñu, Kester; Claßen-Bockhoff, Regine

    2013-01-01

    Backgrounds and Aims Current research in plant science has concentrated on revealing ontogenetic processes of key attributes in plant evolution. One recently discussed model is the ‘transient model’ successful in explaining some types of inflorescence architectures based on two main principles: the decline of the so called ‘vegetativeness’ (veg) factor and the transient nature of apical meristems in developing inflorescences. This study examines whether both principles find a concrete ontogenetic correlate in inflorescence development. Methods To test the ontogenetic base of veg decline and the transient character of apical meristems the ontogeny of meristematic size in developing inflorescences was investigated under scanning electron microscopy. Early and late inflorescence meristems were measured and compared during inflorescence development in 13 eudicot species from 11 families. Key Results The initial size of the inflorescence meristem in closed inflorescences correlates with the number of nodes in the mature inflorescence. Conjunct compound inflorescences (panicles) show a constant decrease of meristematic size from early to late inflorescence meristems, while disjunct compound inflorescences present an enlargement by merging from early inflorescence meristems to late inflorescence meristems, implying a qualitative change of the apical meristems during ontogeny. Conclusions Partial confirmation was found for the transient model for inflorescence architecture in the ontogeny: the initial size of the apical meristem in closed inflorescences is consistent with the postulated veg decline mechanism regulating the size of the inflorescence. However, the observed biphasic kinetics of the development of the apical meristem in compound racemes offers the primary explanation for their disjunct morphology, contrary to the putative exclusive transient mechanism in lateral axes as expected by the model. PMID:23425784

  15. Single Event Effects (SEE) Testing of Embedded DSP Cores within Microsemi RTAX4000D Field Programmable Gate Array (FPGA) Devices

    NASA Technical Reports Server (NTRS)

    Perez, Christopher E.; Berg, Melanie D.; Friendlich, Mark R.

    2011-01-01

    Motivation for this work is: (1) Accurately characterize digital signal processor (DSP) core single-event effect (SEE) behavior (2) Test DSP cores across a large frequency range and across various input conditions (3) Isolate SEE analysis to DSP cores alone (4) Interpret SEE analysis in terms of single-event upsets (SEUs) and single-event transients (SETs) (5) Provide flight missions with accurate estimate of DSP core error rates and error signatures.

  16. Discussions On Worst-Case Test Condition For Single Event Burnout

    NASA Astrophysics Data System (ADS)

    Liu, Sandra; Zafrani, Max; Sherman, Phillip

    2011-10-01

    This paper discusses the failure characteristics of single- event burnout (SEB) on power MOSFETs based on analyzing the quasi-stationary avalanche simulation curves. The analyses show the worst-case test condition for SEB would be using the ion that has the highest mass that would result in the highest transient current due to charge deposition and displacement damage. The analyses also show it is possible to build power MOSFETs that will not exhibit SEB even when tested with the heaviest ion, which have been verified by heavy ion test data on SEB sensitive and SEB immune devices.

  17. A review of experiments and results from the transient reactor test (TREAT) facility.

    SciTech Connect

    Deitrich, L. W.

    1998-07-28

    The TREAT Facility was designed and built in the late 1950s at Argonne National Laboratory to provide a transient reactor for safety experiments on samples of reactor fuels. It first operated in 1959. Throughout its history, experiments conducted in TREAT have been important in establishing the behavior of a wide variety of reactor fuel elements under conditions predicted to occur in reactor accidents ranging from mild off normal transients to hypothetical core disruptive accidents. For much of its history, TREAT was used primarily to test liquid-metal reactor fuel elements, initially for the Experimental Breeder Reactor-II (EBR-II), then for the Fast Flux Test Facility (FFTF), the Clinch River Breeder Reactor Plant (CRBRP), the British Prototype Fast Reactor (PFR), and finally, for the Integral Fast Reactor (IFR). Both oxide and metal elements were tested in dry capsules and in flowing sodium loops. The data obtained were instrumental in establishing the behavior of the fuel under off-normal and accident conditions, a necessary part of the safety analysis of the various reactors. In addition, TREAT was used to test light-water reactor (LWR) elements in a steam environment to obtain fission-product release data under meltdown conditions. Studies are now under way on applications of TREAT to testing of the behavior of high-burnup LWR elements under reactivity-initiated accident (RIA) conditions using a high-pressure water loop.

  18. Comparison of Single Event Transients Generated by Short Pulsed X-Rays, Lasers and Heavy Ions

    SciTech Connect

    Cardoza, David; LaLumondiere, Stephen D.; Tockstein, Michael A.; Brewe, Dale L.; Wells, Nathan P.; Koga, Rokutaro; Gaab, K. M.; Lotshaw, William T.; Moss, Steven C.

    2014-12-01

    We report an experimental study of the transients generated by pulsed x-rays, heavy ions, and different laser wavelengths in a Si p-i-n photodiode. We compare the charge collected by all of the excitation methods to determine the equivalent LET for pulsed x-rays relative to heavy ions. Our comparisons show that pulsed x-rays from synchrotron sources can generate a large range of equivalent LET and generate transients similar to those excited by laser pulses and heavy ion strikes. We also look at how the pulse width of the transients changes for the different excitation methods. We show that the charge collected with pulsed x-rays is greater than expected as the x-ray photon energy increases. Combined with their capability of focusing to small spot sizes and of penetrating metallization, pulsed x-rays are a promising new tool for high resolution screening of SEE susceptibility

  19. Testing the single-state dominance hypothesis

    SciTech Connect

    Álvarez-Rodríguez, R.; Moreno, O.; Moya de Guerra, E.; Sarriguren, P.; Šimkovic, F.; Faessler, A.

    2013-12-30

    We present a theoretical analysis of the single-state dominance hypothesis for the two-neutrino double-beta decay process. The theoretical framework is a proton-neutron QRPA based on a deformed Hartree-Fock mean field with BCS pairing correlations. We focus on the decays of {sup 100}Mo, {sup 116}Cd and {sup 128}Te. We do not find clear evidences for single-state dominance within the present approach.

  20. Oral glucose tolerance test should be performed after stroke and transient ischemic attack.

    PubMed

    Lindsberg, Perttu J; Tuomi, Tiinamaija; Kaste, Markku

    2011-08-01

    Diabetes mellitus predicts an increased risk of stroke, and acute hyperglycemia during acute stroke predicts the presence of undiagnosed diabetes mellitus. Based on recent investigations, 28% of previously nondiabetic stroke or transient ischemic attack patients have undetected diabetes mellitus, and 29% have impaired glucose tolerance, while only 43% have normal glycemic control. Oral glucose tolerance test is a far more sensitive and reliable test of diabetes mellitus than fasting blood glucose or HbA1c, and is recommended in the World Health Organization criteria for diagnosing diabetes mellitus and impaired glucose tolerance. Secondary prevention of stroke is different in patients with diabetes mellitus and the detection of impaired glucose tolerance would ring alarm bells of impending diabetes mellitus and promote lifestyle changes. As screening with inexpensive oral glucose tolerance test would have a hit rate of one in three patients in revealing undetected diabetes mellitus and another one in three in revealing impaired glucose tolerance, it should be implemented in guidelines as an inexpensive test for monitoring stroke and transient ischemic attack patients. PMID:21745342

  1. Transient thermal behaviour of a compressor rotor with ventilation: Test results under simulated engine conditions

    NASA Astrophysics Data System (ADS)

    Reile, E.; Radons, U.; Hennecke, D. K.

    1985-09-01

    The development of advanced compressors for modern aero-engines requires detailed knowledge of the transient thermal behavior of the rotor disks to enable accurate prediction of rotor life and, additionally, of the thermal growth of the rotor for the evaluation of tip clearances. In the quest for longer life and higher reliability of the parts as well as reduced clearances even at transient conditions, the designer has to be able to influence the thermal behavior of the rotor. A very effective way is to vent small amounts of air through the rotor cavities. The design of such a vented rotor is presented. The main emphasis is placed on a detailed description of a test rig specially built for this purpose. The testing was carried out under simulated engine conditions for a wide range of parameters. The results are compared with those obtained with a theoretical model derived from fundamental tests at the University of Sussex, where heat transfer in rotating cavities is investigated. Good agreement is observed. Some final tests were done in an engine. The results also exhibit good agreement with the rig results under simulated conditions, when the proper dimensionless parameters are considered, providing the validity of the simulation.

  2. Predicting the Reliability of Brittle Material Structures Subjected to Transient Proof Test and Service Loading

    NASA Astrophysics Data System (ADS)

    Nemeth, Noel N.; Jadaan, Osama M.; Palfi, Tamas; Baker, Eric H.

    Brittle materials today are being used, or considered, for a wide variety of high tech applications that operate in harsh environments, including static and rotating turbine parts, thermal protection systems, dental prosthetics, fuel cells, oxygen transport membranes, radomes, and MEMS. Designing brittle material components to sustain repeated load without fracturing while using the minimum amount of material requires the use of a probabilistic design methodology. The NASA CARES/Life 1 (Ceramic Analysis and Reliability Evaluation of Structure/Life) code provides a general-purpose analysis tool that predicts the probability of failure of a ceramic component as a function of its time in service. This capability includes predicting the time-dependent failure probability of ceramic components against catastrophic rupture when subjected to transient thermomechanical loads (including cyclic loads). The developed methodology allows for changes in material response that can occur with temperature or time (i.e. changing fatigue and Weibull parameters with temperature or time). For this article an overview of the transient reliability methodology and how this methodology is extended to account for proof testing is described. The CARES/Life code has been modified to have the ability to interface with commercially available finite element analysis (FEA) codes executed for transient load histories. Examples are provided to demonstrate the features of the methodology as implemented in the CARES/Life program.

  3. Aquifer characterization using transient streaming potentials generated by flow during pumping tests - New developments

    NASA Astrophysics Data System (ADS)

    Malama, B.; Kuhlman, K. L.; Revil, A.

    2009-12-01

    Traditional methods of aquifer characterization, namely pumping and slug tests, provide the most direct way of measuring system state variables (hydraulic head) and estimating hydraulic parameters (hydraulic conductivity, specific storage and specific yield) of aquifers. Despite this significant advantage, such methods have some serious limitations: they can be laborious, expensive, are intusive and yield spatially sparse data. Hydrogeophysical methods offer some promise to overcome some of these limitations. We discuss recently developed semi-analytical solutions for transient streaming potentials associated with pumping tests conducted in homogeneous confined and unconfined aquifers. Using these solutions, data obtained from field tests conducted (a) in a confined aquifer at a site located near Montalto Uffugo, in the region of Calabria in Southern Italy, and (b) in an unconfined aquifer at the Boise Hydrogeophysical Research Site (BHRS) in Idaho, US. Estimates of hydraulic parameters that compare well to those obtained by traditional methods were obtained. Our work indicates that transient streaming potential data, collected at land surface, may be used to provide preliminary estimates of hydraulic aquifer properties quickly and cheaply.

  4. Single event upset (SEU) testing at JPL

    NASA Technical Reports Server (NTRS)

    Coss, James R.

    1987-01-01

    It is believed that the increase in SEUs with more modern devices may have serious consequences for future space missions. The physics behind an SEU is discussed as well as SEU test philosophy and equipment, and testing results. It is concluded that the problem may be ameliorated by careful device selection and the use of redundancy or error correction.

  5. Single Event Testing on Complex Devices: Test Like You Fly Versus Test-Specific Design Structures

    NASA Technical Reports Server (NTRS)

    Berg, Melanie D.; Label, Kenneth

    2016-01-01

    We present a mechanism for evaluating complex digital systems targeted for harsh radiation environments such as space. Focus is limited to analyzing the single event upset (SEU) susceptibility of designs implemented inside Field Programmable Gate Array (FPGA) devices. Tradeoffs are provided between application-specific versus test-specific test structures.

  6. Testing IH Instrumentation: Analysis of 1996-1998 Tank Ventilation Data in Terms of Characterizing a Transient Release

    SciTech Connect

    Droppo, James G.

    2004-07-01

    An analysis is conducted of the 1996-1998 Hanford tank ventilation studies of average ventilation rates to help define characteristics of shorter term releases. This effort is being conducted as part of the design of tests of Industrial Hygiene’s (IH) instrumentation ability to detect transient airborne plumes from tanks using current deployment strategies for tank operations. This analysis has improved our understanding of the variability of hourly average tank ventilation processes. However, the analysis was unable to discern the relative importance of emissions due to continuous releases and short-duration bursts of material. The key findings are as follows: 1. The ventilation of relatively well-sealed, passively ventilated tanks appears to be driven by a combination of pressure, buoyancy, and wind influences. The results of a best-fit analysis conducted with a single data set provide information on the hourly emission variability that IH instrumentation will need to detect. 2. Tank ventilation rates and tank emission rates are not the same. The studies found that the measured infiltration rates for a single tank are often a complex function of air exchanges between tanks and air exchanges with outdoor air. This situation greatly limits the usefulness of the ventilation data in defining vapor emission rates. 3. There is no evidence in the data to discern if the routine tank vapor releases occur over a short time (i.e., a puff) or over an extended time (i.e., continuous releases). Based on this analysis of the tank ventilation studies, it is also noted that 1) the hourly averaged emission peaks from the relatively well-sealed passively-vented tanks (such as U-103) are not a simple function of one meteorological parameter – but the peaks often are the result of the coincidence of temporal maximums in pressure, temperature, and wind influences and 2) a mechanistic combination modeling approach and/or field studies may be necessary to understand the short-term temporal characteristics of transient releases - This requirement has implications in both the design of IH field tests and in understanding transient plumes during the times that worker complaints were recorded.

  7. Analysis of single particle diffusion with transient binding using particle filtering.

    PubMed

    Bernstein, Jason; Fricks, John

    2016-07-21

    Diffusion with transient binding occurs in a variety of biophysical processes, including movement of transmembrane proteins, T cell adhesion, and caging in colloidal fluids. We model diffusion with transient binding as a Brownian particle undergoing Markovian switching between free diffusion when unbound and diffusion in a quadratic potential centered around a binding site when bound. Assuming the binding site is the last position of the particle in the unbound state and Gaussian observational error obscures the true position of the particle, we use particle filtering to predict when the particle is bound and to locate the binding sites. Maximum likelihood estimators of diffusion coefficients, state transition probabilities, and the spring constant in the bound state are computed with a stochastic Expectation-Maximization (EM) algorithm. PMID:27107737

  8. Stochastic expression of a multiple antibiotic resistance activator confers transient resistance in single cells

    PubMed Central

    El Meouche, Imane; Siu, Yik; Dunlop, Mary J.

    2016-01-01

    Transient resistance can allow microorganisms to temporarily survive lethal concentrations of antibiotics. This can be accomplished through stochastic mechanisms, where individual cells within a population display diverse phenotypes to hedge against the appearance of an antibiotic. To date, research on transient stochastic resistance has focused primarily on mechanisms where a subpopulation of cells enters a dormant, drug-tolerant state. However, a fundamental question is whether stochastic gene expression can also generate variable resistance levels among growing cells in a population. We hypothesized that stochastic expression of antibiotic-inducible resistance mechanisms might play such a role. To investigate this, we focused on a prototypical example of such a system: the multiple antibiotic resistance activator MarA. Previous studies have shown that induction of MarA can lead to a multidrug resistant phenotype at the population level. We asked whether MarA expression also has a stochastic component, even when uninduced. Time lapse microscopy showed that isogenic cells express heterogeneous, dynamic levels of MarA, which were correlated with transient antibiotic survival. This finding has important clinical implications, as stochastic expression of resistance genes may be widespread, allowing populations to hedge against the sudden appearance of an antibiotic. PMID:26758525

  9. Deep level transient spectroscopy studies of n-type ZnO single crystals grown by different techniques.

    PubMed

    Scheffler, L; Kolkovsky, Vl; Lavrov, E V; Weber, J

    2011-08-24

    In the present study single-crystalline ZnO samples grown from the vapor phase, the melt, and a high-temperature aqueous solution (hydrothermal growth) are investigated before and after hydrogen plasma treatments, by means of deep level transient spectroscopy (DLTS) and high-resolution Laplace DLTS. Dominant DLTS peaks are found to appear in the range of 120-350 K for all materials. The DLTS spectra depend on the procedure of growth of the ZnO. The thermal stabilities of the defects in an oxygen atmosphere and in an oxygen-lean atmosphere are analyzed. The origin of the DLTS peaks is discussed. PMID:21813951

  10. Modeling from Local to Subsystem Level Effects in Analog and Digital Circuits Due to Space Induced Single Event Transients

    NASA Technical Reports Server (NTRS)

    Perez, Reinaldo J.

    2011-01-01

    Single Event Transients in analog and digital electronics from space generated high energetic nuclear particles can disrupt either temporarily and sometimes permanently the functionality and performance of electronics in space vehicles. This work first provides some insights into the modeling of SET in electronic circuits that can be used in SPICE-like simulators. The work is then directed to present methodologies, one of which was developed by this author, for the assessment of SET at different levels of integration in electronics, from the circuit level to the subsystem level.

  11. Investigation of electrically-active deep levels in single-crystalline diamond by particle-induced charge transient spectroscopy

    NASA Astrophysics Data System (ADS)

    Kada, W.; Kambayashi, Y.; Ando, Y.; Onoda, S.; Umezawa, H.; Mokuno, Y.; Shikata, S.; Makino, T.; Koka, M.; Hanaizumi, O.; Kamiya, T.; Ohshima, T.

    2016-04-01

    To investigate electrically-active deep levels in high-resistivity single-crystalline diamond, particle-induced charge transient spectroscopy (QTS) techniques were performed using 5.5 MeV alpha particles and 9 MeV carbon focused microprobes. For unintentionally-doped (UID) chemical vapor deposition (CVD) diamond, deep levels with activation energies of 0.35 eV and 0.43 eV were detected which correspond to the activation energy of boron acceptors in diamond. The results suggested that alpha particle and heavy ion induced QTS techniques are the promising candidate for in-situ investigation of deep levels in high-resistivity semiconductors.

  12. Viral Transmission Dynamics at Single-Cell Resolution Reveal Transiently Immune Subpopulations Caused by a Carrier State Association

    PubMed Central

    Cenens, William; Makumi, Angela; Govers, Sander K.; Lavigne, Rob; Aertsen, Abram

    2015-01-01

    Monitoring the complex transmission dynamics of a bacterial virus (temperate phage P22) throughout a population of its host (Salmonella Typhimurium) at single cell resolution revealed the unexpected existence of a transiently immune subpopulation of host cells that emerged from peculiarities preceding the process of lysogenization. More specifically, an infection event ultimately leading to a lysogen first yielded a phage carrier cell harboring a polarly tethered P22 episome. Upon subsequent division, the daughter cell inheriting this episome became lysogenized by an integration event yielding a prophage, while the other daughter cell became P22-free. However, since the phage carrier cell was shown to overproduce immunity factors that are cytoplasmically inherited by the P22-free daughter cell and further passed down to its siblings, a transiently resistant subpopulation was generated that upon dilution of these immunity factors again became susceptible to P22 infection. The iterative emergence and infection of transiently resistant subpopulations suggests a new bet-hedging strategy by which viruses could manage to sustain both vertical and horizontal transmission routes throughout an infected population without compromising a stable co-existence with their host. PMID:26720743

  13. The Use of Randomization Tests in Single-Subject Research

    ERIC Educational Resources Information Center

    Haardorfer, Regine; Gagne, Phill

    2010-01-01

    Some researchers have argued for the use of or have attempted to make use of randomization tests in single-subject research. To address this tide of interest, the authors of this article describe randomization tests, discuss the theoretical rationale for applying them to single-subject research, and provide an overview of the methodological

  14. The Use of Randomization Tests in Single-Subject Research

    ERIC Educational Resources Information Center

    Haardorfer, Regine; Gagne, Phill

    2010-01-01

    Some researchers have argued for the use of or have attempted to make use of randomization tests in single-subject research. To address this tide of interest, the authors of this article describe randomization tests, discuss the theoretical rationale for applying them to single-subject research, and provide an overview of the methodological…

  15. High-Speed Single-Event Current Transient Measurements in SiGe HBTs

    NASA Technical Reports Server (NTRS)

    Pellish, Jonathan A.; Reed, R.A.; McMorrow, D.; Vizkelethy, G.; Ferlet-Cavrois, V.; Baggio, J.; Paillet, P.; Duhamel, O.; Phillips, S.D.; Sutton, A.K.; Diestelhorst, R.M.; Cressler, J.D.; Dodd, P.E.; Pate, N.D.; Alles, M.L.; Schrimpf, R.D.; Marshall, P.W.; LaBel, K.A.

    2009-01-01

    Time-resolved ion beam induced charge reveals heavy ion response of IBM 5AM SiGe HBT: 1) Position correlation. 2) Unique response for different bias schemes. 3) Similarities to TPA pulsed-laser data. Heavy ion broad-beam transients provide more realistic device response: 1) Feedback using microbeam data 2) Overcome existing issues of LET and ion range with microbeam Both micro- and broad-beam data sets yield valuable input for TCAD simulations. Uncover detailed mechanisms for SiGe HBTs and other devices fabricated on lightly-doped substrates.

  16. Performance of a bulb turbine suitable for low prototype head: model test and transient numerical simulation

    NASA Astrophysics Data System (ADS)

    Zhu, L.; Zhang, H. P.; Zhang, J. G.; Meng, X. C.; Lu, L.

    2012-11-01

    In this paper, a bulb turbine, with unit specific speed of nq=223.1 min-1 suitable for low prototype head was studied from aspect of its performance. Hydraulic model of the turbine was developed firstly, and then model turbine was designed and manufactured. Performance tests were carried out on high-accuracy hydraulic machinery model universal test rig located at IWHR, including energy, cavitation and pressure fluctuation tests, etc. In order to investigate internal flow field, three-dimensional transient turbulence numerical simulation was conducted on the tested turbine, adopting Reynolds-averaged Navier-Stocks control equations and RNG k-ɛ turbulence model. Test and simulation results show that: (1) hydraulic efficiency of model turbine ηM is up to 91.7%, at the optimum operating point of n11o=165.54 r/min versus Q11o=1.93 m3/s; (2) numerical results agree well with experimental resultsby comparing pressure fluctuation, which shows that pressure amplitude is very low at the optimum operating point; (3) hydraulic loss in Outflow domain accounts for more than 50% total hydraulic loss due to flow separation and secondary flow.

  17. Improving referrals for tilt table testing in patients with transient loss of consciousness

    PubMed Central

    Thornton, Luke; Rahunathan, Nithusa; Verma, Narain; Wong, Kenneth

    2016-01-01

    Tilt table testing has been used for over twenty years in the investigation of patients with transient loss of consciousness. The European Society of Cardiology (ESC) recently recommended new guidance regarding indications for tilt table testing. We conducted an educational intervention and produced a new referral proforma that referring clinicians are expected to fill in for all patients referred for tilt table testing. At baseline, 76% (n=84) of referrals for tilt table testing were made in accordance to ESC guidance. Following a simple educational intervention, 100% (n=6) were in line with ESC guidance. After the introduction of the referral proforma, 92% (n=12) of referrals followed ESC guidance. At final data collection, 100% (n=11) of referrals followed ESC guidance. In conclusion, a simple educational intervention and the use of a referral proforma in this quality improvement project have made a sustained difference in improving the appropriateness of referrals for tilt table testing. This has the potential to optimise the efficient use of resources and improve patient care through avoiding unnecessary investigation. PMID:27096093

  18. Single Event Effects (SEE) Testing: Practical Approach to Test Plans

    NASA Technical Reports Server (NTRS)

    LaBel, Kenneth A.; Pellish, Jonathan A.; Berg, Melanie D.

    2014-01-01

    While standards and guidelines for performing SEE testing have existed for several decades, guidance for developing SEE test plans has not been as easy to find. In this presentation, the variety of areas that need to be considered ranging from resource issues (funds, personnel, schedule) to extremely technical challenges (particle interaction and circuit application), shall be discussed. Note: We consider the approach outlined here as a living document: mission specific constraints and new technology related issues always need to be taken into account.

  19. 40 CFR Appendix E to Subpart S of... - Transient Test Driving Cycle

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 89 11.1 90 7.6 91 4.1 92 0.6 93 0 94 0 95 0 96 0 97 0 98 3.3 99 6.6 100 9.9 101 13.2 102 16.5 103 19... transient IM240 test procedure. Second MPH 0 0 1 0 2 0 3 0 4 0 5 3 6 5.9 7 8.6 8 11.5 9 14.3 10 16.9 11 17.3 12 18.1 13 20.7 14 21.7 15 22.4 16 22.5 17 22.1 18 21.5 19 20.9 20 20.4 21 19.8 22 17 23 14.9 24...

  20. Transient Plume Model Testing Using LADEE Spacecraft Attitude Control System Operations

    NASA Technical Reports Server (NTRS)

    Woronowicz, M. S.

    2010-01-01

    The Lunar Atmosphere Dust Environment Explorer (LADEE) spacecraft is being designed for a mission featuring low altitude orbits of the Moon to take relevant ambient measurements before that environment becomes altered by future exploration activities. Instruments include a neutral mass spectrometer capable of measuring ambient species density levels below 100 molecules/cu cm. Coincidentally, with a favorable combination of spacecraft orientations, it is also possible to measure plume gases from LADEE attitude control system thruster operations as they are reflected from the daytime lunar surface and subsequently intercepted by the spacecraft as it orbits overhead. Under such circumstances, it may be possible to test a variety of properties and assumptions associated with various transient plume models or to infer certain aspects regarding lunar surface properties.

  1. Transient Plume Model Testing Using LADEE Spacecraft Attitude Control System Operations

    SciTech Connect

    Woronowicz, M. S.

    2011-05-20

    The Lunar Atmosphere Dust Environment Explorer (LADEE) spacecraft is being designed for a mission featuring low altitude orbits of the Moon to take relevant ambient measurements before that environment becomes altered by future exploration activities. Instruments include a neutral mass spectrometer capable of measuring ambient species density levels below 100 molecules/cm{sup 3}. Coincidentally, with a favorable combination of spacecraft orientations, it is also possible to measure plume gases from LADEE attitude control system thruster operations as they are reflected from the daytime lunar surface and subsequently intercepted by the spacecraft as it orbits overhead. Under such circumstances, it may be possible to test a variety of properties and assumptions associated with various transient plume models or to infer certain aspects regarding lunar surface properties.

  2. 40 CFR Appendix E to Subpart S of... - Transient Test Driving Cycle

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36.2 162 37.3 163 39.3 164 40.5 165 42.1 166 43.5 167 45.1 168 46 169 46.8 170 47.5 171 47.5 172 47.3... transient IM240 test procedure. Second MPH 0 0 1 0 2 0 3 0 4 0 5 3 6 5.9 7 8.6 8 11.5 9 14.3 10 16.9 11 17.3 12 18.1 13 20.7 14 21.7 15 22.4 16 22.5 17 22.1 18 21.5 19 20.9 20 20.4 21 19.8 22 17 23 14.9 24...

  3. Heat and Mass Transfer Analysis of Dehumidifiers Using Adiabatic Transient Tests

    SciTech Connect

    Maclaine-Cross, I. L.; Pesaran, A. A.

    1986-04-01

    Adiabatic step transient data were obtained for two dehumidifier test matrices, using parallel plates with crushed silica gel and staggered parallel strips coated with microbead silica gel. The data were analyzed using the statistical moments method and combined heat and mass transfer analogy theory. The analysis showed that the average overall Nusselt number in both matrices was about 40% to 50% lower than laminar flow predictions. The average overall Nusselt number for the microbead staggered matrix was about 85% larger than that of the crushed silica-gel parallel-plate matrix. The Nusselt number/friction factor Reynolds number ratio (Nu/fRe) of the microbead, staggered parallel-strip matrix was about 28% larger than that of the crushed silica-gel parallel-plate matrix. These results were explained by the presence of a stagnant gas film. The results showed that compact, high-performance, rotary dehumidifiers for desiccant cooling systems are possible and economical.

  4. Measuring the Optical Performance of Evacuated Receivers via an Outdoor Thermal Transient Test: Preprint

    SciTech Connect

    Kutscher, C.; Burkholder, F.; Netter, J.

    2011-08-01

    Modern parabolic trough solar collectors operated at high temperatures to provide the heat input to Rankine steam power cycles employ evacuated receiver tubes along the collector focal line. High performance is achieved via the use of a selective surface with a high absorptance for incoming short-wave solar radiation and a low emittance for outgoing long-wave infrared radiation, as well as the use of a hard vacuum to essentially eliminate convective and conductive heat losses. This paper describes a new method that determines receiver overall optical efficiency by exposing a fluid-filled, pre-cooled receiver to one sun outdoors and measuring the slope of the temperature curve at the point where the receiver temperature passes the glass envelope temperature (that is, the point at which there is no heat gain or loss from the absorber). This transient test method offers the potential advantages of simplicity, high accuracy, and the use of the actual solar spectrum.

  5. Photo-induced current transient spectroscopy of single crystal Tl6I4Se

    NASA Astrophysics Data System (ADS)

    Liu, Z.; Peters, J. A.; Sebastian, M.; Kanatzidis, M. G.; Im, J.; Freeman, A. J.; Wessels, B. W.

    2014-11-01

    The compound Tl6I4Se is a promising wide band gap semiconductor for hard radiation detection at room temperature. To further improve its detection efficiency, native defects have been investigated using photo-induced current transient spectroscopy (PICTS). We observe two shallow acceptor levels with mean activation energies of 76, 175 meV, and two shallow donor defects 62, and 96 meV, respectively. No deeper donor levels are observed. The levels are attributed to native point defects. Defect capture cross sections in the range 10-21 to 10-18 cm2 were measured. The small capture cross sections are attributed to the effective screening of the defects due to a large static dielectric constant.

  6. Single shaft automotive gas turbine engine characterization test

    NASA Technical Reports Server (NTRS)

    Johnson, R. A.

    1979-01-01

    An automotive gas turbine incorporating a single stage centrifugal compressor and a single stage radial inflow turbine is described. Among the engine's features is the use of wide range variable geometry at the inlet guide vanes, the compressor diffuser vanes, and the turbine inlet vanes to achieve improved part load fuel economy. The engine was tested to determine its performance in both the variable geometry and equivalent fixed geometry modes. Testing was conducted without the originally designed recuperator. Test results were compared with the predicted performance of the nonrecuperative engine based on existing component rig test maps. Agreement between test results and the computer model was achieved.

  7. Barometric pressure transient testing applications at the Nevada Test Site. Nuclear chimney analysis. Final report

    SciTech Connect

    Hanson, J.M.

    1985-12-01

    Investigations of barometric pressure testing of NTS nuclear chimneys were reviewed. This review includes the models used in the interpretation, methods of analysis, and results. Analytic and semi-analytic models were presented and applied to both historical data and new data taken for this current project. An interpretation technique based on non-linear least squares methods was used to analyze this data in terms of historic and more recent chimney models. Finally, a detailed discussion of radioactive gas transport due to surface barometric pressure fluctuations was presented. This mechanism of transport, referred to as ''barometric pumping,'' is presented in terms of conditions likely to be encountered at the NTS. The report concludes with a discussion of the current understanding of gas flow properties in the alluvial and volcanic areas of the NTS, and suggestions for future efforts directed toward increasing this understanding are presented.

  8. Hanford single shell tank saltcake cesium removal test plan

    SciTech Connect

    Duncan, J.B., Westinghouse Hanford

    1996-12-11

    This document provides the test preparation and conduct of a cesium removal test using Hanford Single Shell Tank Saltcake from tanks 241-BY-110, 241-U-108, 241 U 109, 241-A-101, and 241-S-102 in a benchscale column. The cesium sorbent to be tested is crystalline silicotitanate

  9. Particle Tracking-Based Strategies For Simulating Transport in a Transient Groundwater Flow Field at Yucca Flat, Nevada Test Site, USA

    NASA Astrophysics Data System (ADS)

    Keating, E. H.; Srinivasan, G.; Kang, Q.; Li, C.; Dash, Z.; Kwicklis, E. M.

    2009-12-01

    Developing probabilistic-based calculations of contaminant concentrations over the next 1000 years at Yucca Flat, Nevada Test site, require tremendous computational effort in this highly complex hydrogeologic surface environment. The sources of contamination, underground nuclear tests conducted between 1951 and 1992, not only released radionuclides to the subsurface but also created abrupt, significant changes in rock properties and caused large transients in the measured hydraulic gradients. To efficiently model contaminant migration from these sources we use a particle-based approach within a transient flow field. Here, we present results using two methods; first, an explicit representation of time-varying sources using large numbers of particles introduced at source-specific rates over time, each representing a unique mass of solute. This method provides good results, but is computationally expensive since sensitivity to uncertainty in source term and transport parameters can only be explored with discrete process-model runs. The second method employs a convolution method (PLUMECALC) which can efficiently consider a large number of variations in the source terms and in certain transport parameters with a single process-model run. Implementation of this second approach required extension of the existing methodology to conditions of transient flow. We find very good comparison between the two methods on small test problems and excellent computational advantages when applying the convolution method in the NTS application

  10. Stochastic inversion of sequential hydraulic tests for transient and highly permeable unconfined aquifer systems

    NASA Astrophysics Data System (ADS)

    Ni, C.-F.; Huang, Y.-J.; Yeh, T.-C. J.; Dong, J.-J.; Chen, J.-S.; Li, M.-H.

    2013-12-01

    A hydraulic tomography survey (HTS) is a conceptually improved technique that has been recognized to be efficient for estimating high-resolution aquifer parameters. Based on the concept of HTS, this study presents a modified stochastic inverse model for estimating hydraulic conductivity (K) and specific yield (Sy) in shallow and highly permeable unconfined aquifers. A well field with 15 fully screened wells was developed for the purpose of model implementations. In this study a synthetic example was first employed to assess the accuracy of the inverse model. We then implemented the model to field-scale, cross-hole injection tests in a shallow and highly permeable unconfined aquifer near the middle reach of the Wu River in central Taiwan. To assess the effect of constant head boundary conditions on the estimation results, two additional modeling domains were evaluated based on the same field data from the injection tests. Results for the synthetic example show that the modified inverse model can reproduce well the predefined geologic features of the unconfined aquifer. The inverse model can estimate accurately the ln K patterns and magnitudes. However, slightly fewer details of the ln Sy field are obtained due to the insensitivity of transient hydraulic stresses for specified sampling times. Model implementations of field-scale injection tests show that the model can estimate ln K and ln Sy fields with high spatial resolution. The estimated K and Sy values for the test site vary by one order of magnitude, indicating a relatively homogeneous aquifer for the tested well field. Results based on three different modeling domains show similar patterns and magnitudes of ln K and ln Sy near the well locations. This result suggests that the case with domain 40 m × 20 m should be sufficient for the injection tests at the well field.

  11. Impacts Analyses Supporting the National Environmental Policy Act Environmental Assessment for the Resumption of Transient Testing Program

    SciTech Connect

    Annette L. Schafer; Lloyd C. Brown; David C. Carathers; Boyd D. Christensen; James J. Dahl; Mark L. Miller; Cathy Ottinger Farnum; Steven Peterson; A. Jeffrey Sondrup; Peter V. Subaiya; Daniel M. Wachs; Ruth F. Weiner

    2013-11-01

    Environmental and health impacts are presented for activities associated with transient testing of nuclear fuel and material using two candidate test reactors. Transient testing involves irradiation of nuclear fuel or materials for short time-periods under high neutron flux rates. The transient testing process includes transportation of nuclear fuel or materials inside a robust shipping cask to a hot cell, removal from the shipping cask, pre-irradiation examination of the nuclear materials, assembly of an experiment assembly, transportation of the experiment assembly to the test reactor, irradiation in the test reactor, transport back to the hot cell, and post-irradiation examination of the nuclear fuel or material. The potential for environmental or health consequences during the transportation, examination, and irradiation actions are assessed for normal operations, off-normal (accident) scenarios, and transportation. Impacts to the environment (air, soil, and groundwater), are assessed during each phase of the transient testing process. This report documents the evaluation of potential consequences to the general public. This document supports the Environmental Assessment (EA) required by the U.S. National Environmental Policy Act (NEPA) (42 USC Subsection 4321 et seq.).

  12. Single Event Effects Testing of the Linfinity SG1525A Pulse Width Modulator Controller

    NASA Technical Reports Server (NTRS)

    Howard, J. W., Jr.; Carts, M. A.; LaBel, K. A.; Forney, J. D.; Irwin, T. L.

    2003-01-01

    Pulse Width Modulator (PWM) Controllers are the heart of switching power supply systems in development today. The PWMs considered here have the same integration advantages as many other controllers but it also includes the interface drivers for the follow-on power Field Effect Transistors (FET). Previous work on these types of devices looked into the required test methodologies [ 11 and the impact of radiation on the soft start and shutdown circuits of typically incorporated in the technology [2]. Taking advantage of this previous work this study was undertaken to determine the single event destructive and transient susceptibility of the Linfinity SG1525A Pulse Width Modulator Controller. The device was monitored for transient interruptions in the output signals and for destructive events induced by exposing it to a heavy ion beam at the Texas A&M University Cyclotron Single Event Effects Test Facility. After exposing these devices to the beam, a new upset mode has been identified that can lead to catastrophic power supply system failure if this event would occur while drive power FETs off the two device outputs. The devices and the test methods used will be described first. This will be followed by a brief description of the data collected to date (not all data can be presented with the length constraints of the summary) and a summary of the key results.

  13. Properties of voltage-activated [Ca2+]i transients in single smooth muscle cells isolated from pregnant rat uterus

    PubMed Central

    Shmigol, A V; Eisner, D A; Wray, Susan

    1998-01-01

    The intracellular calcium concentration ([Ca2+]i) was measured at 35 °C using the fluorescent indicator indo-1 in patch-clamped, single uterine myocytes from pregnant rats to investigate the relationship between depolarization, Ca2+ current (ICa) and [Ca2+]i. Membrane depolarization activated ICa and produced a [Ca2+]i transient. The rapid increase in [Ca2+]i occurred at the same time as the inward ICa. Both ICa and the increase in [Ca2+]i were abolished by nifedipine (10 μm). When the membrane potential was held at -80 mV the threshold depolarization for an increase in [Ca2+]i was about -55 to -50 mV. As the magnitude of the depolarization was increased to about 0 mV there was an increase in the size of both ICa and the increase in [Ca2+]i. As the magnitude of the depolarization was further increased both ICa and the [Ca2+]i increase declined. When the depolarizing pulses were applied at 3 Hz to mimic normal action potentials then the individual [Ca2+]i transients did not fully relax and a tetanic rise of [Ca2+]i was observed. Under these conditions, there was not a simple relationship between the magnitude of the Ca2+ response and Ca2+ entry. When pairs of depolarizing pulses were applied, the increase in [Ca2+]i produced by the second pulse was larger (in relation to the magnitude of the L-type Ca2+ current) than that produced by the first pulse. This facilitation was abolished by both ryanodine and cyclopiazonic acid suggesting a role for release from intracellular stores. We conclude that the L-type Ca2+ current is the major source of Ca2+ ions entering the cell to produce the [Ca2+]i transient on depolarization. The magnitude of the increase in [Ca2+]i may, however, be amplified by Ca2+-induced Ca2+ release. PMID:9714861

  14. High intensity single bunch operation with heavy periodic transient beam loading in wide band rf cavities

    NASA Astrophysics Data System (ADS)

    Tamura, Fumihiko; Hotchi, Hideaki; Schnase, Alexander; Yoshii, Masahito; Yamamoto, Masanobu; Ohmori, Chihiro; Nomura, Masahiro; Toda, Makoto; Shimada, Taihei; Hasegawa, Katsushi; Hara, Keigo

    2015-09-01

    The rapid cycling synchrotron (RCS) in the Japan Proton Accelerator Research Complex (J-PARC) was originally designed to accelerate two high intensity bunches, while some of neutron experiments in the materials and life science experimental facility and a muon experiment using main ring beams require a single bunch operation mode, in which one of the two rf buckets is filled and the other is empty. The beam intensity in the single bunch operation has been limited by longitudinal beam losses due to the rf bucket distortions by the wake voltage of the odd harmonics (h =1 ,3 ,5 ) in the wide band magnetic alloy cavities. We installed an additional rf feedforward system to compensate the wake voltages of the odd harmonics (h =1 ,3 ,5 ). The additional system has a similar structure as the existing feedforward system for the even harmonics (h =2 ,4 ,6 ). We describe the function of the feedforward system for the odd harmonics, the commissioning methodology, and the commissioning results. The longitudinal beam losses during the single bunch acceleration disappeared with feedforward for the odd harmonics. We also confirmed that the beam quality in the single bunch acceleration are similar to that of the normal operation with two bunches. Thus, high intensity single bunch acceleration at the intensity of 2.3 ×1013 protons per bunch has been achieved in the J-PARC RCS. This article is a follow-up of our previous article, Phys. Rev. ST Accel. Beams 14, 051004 (2011). The feedforward system extension for single bunch operation was successful.

  15. Impacts Analyses Supporting the National Environmental Policy Act Environmental Assessment for the Resumption of Transient Testing Program

    SciTech Connect

    Annette L. Schafer; LLoyd C. Brown; David C. Carathers; Boyd D. Christensen; James J. Dahl; Mark L. Miller; Cathy Ottinger Farnum; Steven Peterson; A. Jeffrey Sondrup; Peter V. Subaiya; Daniel M. Wachs; Ruth F. Weiner

    2014-02-01

    This document contains the analysis details and summary of analyses conducted to evaluate the environmental impacts for the Resumption of Transient Fuel and Materials Testing Program. It provides an assessment of the impacts for the two action alternatives being evaluated in the environmental assessment. These alternatives are (1) resumption of transient testing using the Transient Reactor Test Facility (TREAT) at Idaho National Laboratory (INL) and (2) conducting transient testing using the Annular Core Research Reactor (ACRR) at Sandia National Laboratory in New Mexico (SNL/NM). Analyses are provided for radiologic emissions, other air emissions, soil contamination, and groundwater contamination that could occur (1) during normal operations, (2) as a result of accidents in one of the facilities, and (3) during transport. It does not include an assessment of the biotic, cultural resources, waste generation, or other impacts that could result from the resumption of transient testing. Analyses were conducted by technical professionals at INL and SNL/NM as noted throughout this report. The analyses are based on bounding radionuclide inventories, with the same inventories used for test materials by both alternatives and different inventories for the TREAT Reactor and ACRR. An upper value on the number of tests was assumed, with a test frequency determined by the realistic turn-around times required between experiments. The estimates provided for impacts during normal operations are based on historical emission rates and projected usage rates; therefore, they are bounding. Estimated doses for members of the public, collocated workers, and facility workers that could be incurred as a result of an accident are very conservative. They do not credit safety systems or administrative procedures (such as evacuation plans or use of personal protective equipment) that could be used to limit worker doses. Doses estimated for transportation are conservative and are based on transport of the bounding radiologic inventory that will be contained in any given test. The transportation analysis assumes all transports will contain the bounding inventory.

  16. 49 CFR 238.311 - Single car test.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Director of the Federal Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51. You may obtain a... 49 Transportation 4 2012-10-01 2012-10-01 false Single car test. 238.311 Section 238.311... Requirements for Tier I Passenger Equipment § 238.311 Single car test. (a) Except for self-propelled...

  17. 49 CFR 238.311 - Single car test.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Director of the Federal Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51. You may obtain a... 49 Transportation 4 2011-10-01 2011-10-01 false Single car test. 238.311 Section 238.311... Requirements for Tier I Passenger Equipment § 238.311 Single car test. (a) Except for self-propelled...

  18. 49 CFR 238.311 - Single car test.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Director of the Federal Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51. You may obtain a... 49 Transportation 4 2013-10-01 2013-10-01 false Single car test. 238.311 Section 238.311... Requirements for Tier I Passenger Equipment § 238.311 Single car test. (a) Except for self-propelled...

  19. 49 CFR 238.311 - Single car test.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Director of the Federal Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51. You may obtain a... 49 Transportation 4 2014-10-01 2014-10-01 false Single car test. 238.311 Section 238.311... Requirements for Tier I Passenger Equipment § 238.311 Single car test. (a) Except for self-propelled...

  20. Information-gap robustness for the test analysis correlation of nonlinear transient simulation

    SciTech Connect

    Hemez, F. M.; Ben-Haim, Yakov,; Cogan, S.

    2002-01-01

    An alternative to the theory of probability is applied to the problem of assessing the robustness of test-analysis correlation to parametric sources of uncertainty. The analysis technique is based on the theory of information-gap, which models the clustering of uncertain events in families of nested sets instead of assuming a probability structure. The system investigated is the propagation of a transient impact through a layer of hyper-elastic material. The two sources of non-linearity are the softening of the constitutive law implemented to model the hyper-elastic material and contact dynamics at the interface between metallic and crushable materials. The robustness of test-analysis correlation to sources of parametric variability is first studied to identify the parameters of the model that significantly influence the agreement between measurements and predictions. Calibration under non-probabilistic uncertainty is then illustrated. Finally, two information-gap models of uncertainty are embedded to represent uncertainty not only in the knowledge of the model's parameters but also in the form of the model itself. Although computationally expensive, it is demonstrated that the information-gap reasoning can greatly enhance our understanding of a moderately complex system when the theory of probability cannot be applied due to insufficient information.

  1. Development of single fluid volume element method for simulation of transient fluid flow in self-siphons

    NASA Astrophysics Data System (ADS)

    Viridi, S.; Novitrian, Nurhayati, Hidayat, W.; Latief, F. D. E.; Zen, F. P.

    2014-09-01

    A simple model for transient flow in a narrow pipe is presented in this work. The model is simply derived from Newton's second law of motion. As an example it is used to predict flow occurrence in two forms of self-siphon, which are inverted-U and M-like forms. Simulation for system consists only a vertical pipe is also presented since it is actually part of the both siphon systems. For the simple systems the model can have good predictions but for the complex system it can only have 89.6 % good prediction. Its simplicity can be used to illustrate how the interface between fluid and air, single fluid volume element (SFVE) moves along the siphon. The method itself is named as SFVE method.

  2. Characterization of deep level defects in Tl6I4S single crystals by photo-induced current transient spectroscopy

    NASA Astrophysics Data System (ADS)

    Peters, J. A.; Liu, Z.; Im, J.; Nguyen, S.; Sebastian, M.; Freeman, A. J.; Kanatzidis, M. G.; Wessels, B. W.

    2015-02-01

    Defect levels in semi-insulating Tl6I4S single crystals grown by the horizontal Bridgman technique have been characterized using photo-induced current transient spectroscopy (PICTS). These measurements revealed six electron traps located at (0.059? ?0.007), (0.13? ?0.012), (0.31? ?0.074), (0.39? ?0.019), (0.62? ?0.110), and (0.597? ?0.105). These defect levels are attributed to vacancies (VI, VS) and antisite defects (IS, TlS, TlI) upon comparison to calculations of native defect energy levels using density functional theory and defects recently reported from photoluminescence and photoconductivity measurements.

  3. Modeling of single event transients with dual double-exponential current sources: Implications for logic cell characterization

    SciTech Connect

    Black, Dolores Archuleta; Robinson, William H.; Wilcox, Ian Zachary; Limbrick, Daniel B.; Black, Jeffrey D.

    2015-08-07

    Single event effects (SEE) are a reliability concern for modern microelectronics. Bit corruptions can be caused by single event upsets (SEUs) in the storage cells or by sampling single event transients (SETs) from a logic path. Likewise, an accurate prediction of soft error susceptibility from SETs requires good models to convert collected charge into compact descriptions of the current injection process. This paper describes a simple, yet effective, method to model the current waveform resulting from a charge collection event for SET circuit simulations. The model uses two double-exponential current sources in parallel, and the results illustrate why a conventional model based on one double-exponential source can be incomplete. Furthermore, a small set of logic cells with varying input conditions, drive strength, and output loading are simulated to extract the parameters for the dual double-exponential current sources. As a result, the parameters are based upon both the node capacitance and the restoring current (i.e., drive strength) of the logic cell.

  4. Modeling of single event transients with dual double-exponential current sources: Implications for logic cell characterization

    SciTech Connect

    Black, Dolores A.; Robinson, William H.; Limbrick, Daniel B.; Black, Jeffrey D.; Wilcox, Ian Z.

    2015-08-07

    Single event effects (SEE) are a reliability concern for modern microelectronics. Bit corruptions can be caused by single event upsets (SEUs) in the storage cells or by sampling single event transients (SETs) from a logic path. An accurate prediction of soft error susceptibility from SETs requires good models to convert collected charge into compact descriptions of the current injection process. This paper describes a simple, yet effective, method to model the current waveform resulting from a charge collection event for SET circuit simulations. The model uses two double-exponential current sources in parallel, and the results illustrate why a conventional model based on one double-exponential source can be incomplete. A small set of logic cells with varying input conditions, drive strength, and output loading are simulated to extract the parameters for the dual double-exponential current sources. Furthermore, the parameters are based upon both the node capacitance and the restoring current (i.e., drive strength) of the logic cell.

  5. Modeling of single event transients with dual double-exponential current sources: Implications for logic cell characterization

    DOE PAGESBeta

    Black, Dolores Archuleta; Robinson, William H.; Wilcox, Ian Zachary; Limbrick, Daniel B.; Black, Jeffrey D.

    2015-08-07

    Single event effects (SEE) are a reliability concern for modern microelectronics. Bit corruptions can be caused by single event upsets (SEUs) in the storage cells or by sampling single event transients (SETs) from a logic path. Likewise, an accurate prediction of soft error susceptibility from SETs requires good models to convert collected charge into compact descriptions of the current injection process. This paper describes a simple, yet effective, method to model the current waveform resulting from a charge collection event for SET circuit simulations. The model uses two double-exponential current sources in parallel, and the results illustrate why a conventionalmore » model based on one double-exponential source can be incomplete. Furthermore, a small set of logic cells with varying input conditions, drive strength, and output loading are simulated to extract the parameters for the dual double-exponential current sources. As a result, the parameters are based upon both the node capacitance and the restoring current (i.e., drive strength) of the logic cell.« less

  6. Modeling of single event transients with dual double-exponential current sources: Implications for logic cell characterization

    DOE PAGESBeta

    Black, Dolores A.; Robinson, William H.; Limbrick, Daniel B.; Black, Jeffrey D.; Wilcox, Ian Z.

    2015-08-07

    Single event effects (SEE) are a reliability concern for modern microelectronics. Bit corruptions can be caused by single event upsets (SEUs) in the storage cells or by sampling single event transients (SETs) from a logic path. An accurate prediction of soft error susceptibility from SETs requires good models to convert collected charge into compact descriptions of the current injection process. This paper describes a simple, yet effective, method to model the current waveform resulting from a charge collection event for SET circuit simulations. The model uses two double-exponential current sources in parallel, and the results illustrate why a conventional modelmore » based on one double-exponential source can be incomplete. A small set of logic cells with varying input conditions, drive strength, and output loading are simulated to extract the parameters for the dual double-exponential current sources. Furthermore, the parameters are based upon both the node capacitance and the restoring current (i.e., drive strength) of the logic cell.« less

  7. COMMIX-1AR/P: A three-dimensional transient single-phase computer program for thermal hydraulic analysis of single and multicomponent systems

    SciTech Connect

    Blomquist, R.N.; Garner, P.L; Gelbard, E.M.

    1991-07-01

    The COMMIX-1AR/P computer code is designed for analyzing the steady-state and transient aspects of single-phase fluid flow and heat transfer in three spatial dimensions. This version is an extension of the modeling in COMMIX-1A to include multiple fluids in physically separate regions of the computational domain, modeling descriptions for pumps, radiation heat transfer between surfaces of the solids which are embedded in or surround the fluid, a k-{var epsilon} model for fluid turbulence, and improved numerical techniques. The porous-medium formulation in COMMIX allows the code to be applied to a wide range of problems involving both simple and complex geometrical arrangements. The basic equations, underlying assumptions, and solution techniques are presented for the entire computer code, covering both old and new features. 37 refs., 18 figs., 17 tabs.

  8. COMMIX-1AR/P: A three-dimensional transient single-phase computer program for thermal hydraulic analysis of single and multicomponent systems

    SciTech Connect

    Garner, P.L.; Blomquist, R.N.; Gelbard, E.M.

    1992-09-01

    The COMMIX-1AR/P computer program is designed for analyzing the steady-state and transient aspects of single-phase fluid flow and heat transfer in three spatial dimensions. This version is an extension of the modeling in COMMIX-1A to include multiple fluids in physically separate regions of the computational domain, modeling descriptions for pumps, radiation heat transfer between surfaces of the solids which are embedded in or surround the fluid, a k-[var epsilon] model for fluid turbulence, and improved numerical techniques. The porous-medium formulation in COMMIX allows the program to be applied to a wide range of problems involving both simple and complex geometrical arrangements. The input preparation and execution procedures are presented for the COMMIX-1AR/P program and several postprocessor programs which produce graphical displays of the calculated results.

  9. Anomalous transient uplift observed at the Lop Nor, China nuclear test site using satellite radar interferometry time-series analysis

    NASA Astrophysics Data System (ADS)

    Vincent, P.; Buckley, S. M.; Yang, D.; Carle, S. F.

    2011-12-01

    Anomalous uplift is observed at the Lop Nor, China nuclear test site using ERS satellite SAR data. Using an InSAR time-series analysis method, we show that an increase in absolute uplift with time is observed between 1997 and 1999. The signal is collocated with past underground nuclear tests. Due to the collocation in space with past underground tests we postulate a nuclear test-related hydrothermal source for the uplift signal. A possible mechanism is presented that can account for the observed transient uplift and is consistent with documented thermal regimes associated with underground nuclear tests conducted at the Nevada National Security Site (NNSS) (formerly the Nevada Test Site).

  10. Photo-induced current transient spectroscopy of defects in single crystals of synthetic diamond

    NASA Astrophysics Data System (ADS)

    Odrinskii, A. P.; Kazyuchits, N. M.; Makarenko, L. F.

    2015-11-01

    The kinetics of photocurrent relaxation in synthetic diamond single crystals with an electrical resistivity of ˜1014 Ω · cm in the temperature range of 440-550 K has been investigated. It has been found that there are two processes of thermal emission of charge carriers, which are detected simultaneously. The suppression of the contribution to the relaxation from one of the processes with an increase in the temperature has been interpreted as the formation of a coupling between the detected processes. The possibilities of the mutual influence between the processes of charge carrier emission have been discussed.

  11. Transient Response of Single-Domain Y-Ba-Cu-O Rings to Pulsed Magnetic Fields

    NASA Astrophysics Data System (ADS)

    Askew, T. R.; Weber, J. M.; Cha, Y. S.; Claus, H.; Veal, B. W.

    2002-08-01

    Shielding current limits and magnetic diffusion characteristics have been measured at 77 K for a set of YBCO single-domain rings. These were fabricated from melt-textured cylindrical YBCO monoliths that were densified to nearly 100%, and then oriented from a single seed. The rings were surrounded by a drive coil that can, under pulse conditions, achieve applied magnetic fields in excess of 1 T and induce currents in excess of 50 kA. Simultaneous magnetic characterization with a Rogowski coil and Hall probe was used to determine the induced current in the sample and the magnetic field in the center of the sample. Magnetic fields trapped in the samples were mapped with a scanning Hall probe. When compared with similar measurements on multidomain c-axisoriented YBCO rings, the flux penetration is faster and more uniform around the circumference of the ring. The observed critical current density, 15,000 A/cm2 at 77 K, is suitable for application in penetration-type fault current limiters. Separate measurements of the trapped magnetic field and critical current density in the rings are compared with results obtained by analysis of magnetic diffusion characteristics.

  12. A thermal formulation for single-wall quenching of transient laminar flames

    SciTech Connect

    Boust, B.; Sotton, J.; Labuda, S.A.; Bellenoue, M.

    2007-05-15

    Improving our knowledge of flame-wall interaction is of relevance to performing near-wall combustion calculations. Quenching distance is to be determined accordingly, as a major parameter of flame quenching. For this purpose, an equation describing the behavior of single-wall flame quenching has been derived from a simplified model of laminar flame-wall interaction. It allows evaluating quenching distance from wall heat flux and mixture properties; a significant advantage of this formula is the absence of any empirical coefficient. To assess its reliability, the results computed with this equation have been compared to experimental data concerning laminar flame-wall interaction. For this purpose, single-wall quenching parameters have been recorded in both head-on and sidewall configurations. Quenching distance and wall heat flux have been measured simultaneously, during the combustion of quiescent methane-air mixtures in a constant-volume vessel. Quenching distance is determined through direct visualization, whereas wall heat flux is processed from the time evolution of wall surface temperature. The equation has been verified over the pressure range 0.05-0.35 MPa in stoichiometric and lean mixtures. It shows good agreement with experimental data at first order, with less than 20% variation. (author)

  13. Cosmic Transients Test Einstein's Equivalence Principle out to GeV Energies

    NASA Astrophysics Data System (ADS)

    Gao, He; Wu, Xue-Feng; Mészáros, Peter

    2015-09-01

    The Einstein Equivalence Principle (EEP) can be probed with astrophysical sources emitting simultaneously different types of neutral particles, or particles with varying energies, by testing their time of flight through the same gravitational field. Here we use the time delays between correlated photons from cosmological transients to constrain the accuracy of the EEP. We take data from two gamma-ray bursts as an example and, as a lower limit to the theoretical time delays between different energies, we use delays arising from only the gravitational field of our own galaxy. We then show that the parameterized post-Newtonian parameter γ is the same for photons over energy ranges between eV and MeV and between MeV and GeV to a part in 10-7, which is at least one order of magnitude better than previous limits. Combining this bound on the wavelength dependence of γ with the absolute bound | γ -1| \\lt 0.3% from light-deflection measurements at optical (eV) wavelengths, we thus extend this absolute bound on γ to GeV energies.

  14. Compendium of Test Results of Recent Single Event Effect Tests Conducted by the Jet Propulsion Laboratory

    NASA Technical Reports Server (NTRS)

    McClure, Steven S.; Allen, Gregory R.; Irom, Farokh; Scheick, Leif Z.; Adell, Philippe C.; Miyahira, Tetsuo F.

    2010-01-01

    This paper reports heavy ion and proton-induced single event effect (SEE) results from recent tests for a variety of microelectronic devices. The compendium covers devices tested over the last two years by the Jet Propulsion Laboratory.

  15. Heavy ion induced Single Event Phenomena (SEP) data for semiconductor devices from engineering testing

    NASA Technical Reports Server (NTRS)

    Nichols, Donald K.; Huebner, Mark A.; Price, William E.; Smith, L. S.; Coss, James R.

    1988-01-01

    The accumulation of JPL data on Single Event Phenomena (SEP), from 1979 to August 1986, is presented in full report format. It is expected that every two years a supplement report will be issued for the follow-on period. This data for 135 devices expands on the abbreviated test data presented as part of Refs. (1) and (3) by including figures of Single Event Upset (SEU) cross sections as a function of beam Linear Energy Transfer (LET) when available. It also includes some of the data complied in the JPL computer in RADATA and the SPACERAD data bank. This volume encompasses bipolar and MOS (CMOS and MHNOS) device data as two broad categories for both upsets (bit-flips) and latchup. It also includes comments on less well known phenomena, such as transient upsets and permanent damage modes.

  16. Calcium transients during early development in single starfish (Asterias forbesi) oocytes

    SciTech Connect

    Eisen, A.; Reynolds, G.T.

    1984-11-01

    Maturation and fertilization of the starfish oocyte are putative calcium-dependent events. The authors have investigated the spatial distribution and temporal dynamics of this calcium dependence in single oocytes of Asterias forbesi. They used the calcium photoprotein, aequorin, in conjunction with a microscope-photomultiplier and microscope-image intensifier. Surprisingly, in contrast to earlier work with Marasthenias glacialis, there is no detectable increase in intracellular-free calcium in the oocyte of A. forbesi in response to the maturation hormone 1-methyl adenine. During fertilization of the same, matured, A. forbesi oocyte there is a large increase in intracellular-free calcium. The calcium concentration increases to approx.1 ..mu..M at the point of insemination and the region of elevated free calcium expands across the oocyte in approx.20 s (17-19/sup 0/C). After the entire oocyte reaches an elevated concentration of free calcium, the concentration decreases uniformly throughout the oocyte over the next several minutes.

  17. SINGLE EVENT EFFECTS TEST FACILITY AT OAK RIDGE NATIONAL LABORATORY

    SciTech Connect

    Riemer, Bernie; Gallmeier, Franz X; Dominik, Laura J

    2015-01-01

    Increasing use of microelectronics of ever diminishing feature size in avionics systems has led to a growing Single Event Effects (SEE) susceptibility arising from the highly ionizing interactions of cosmic rays and solar particles. Single event effects caused by atmospheric radiation have been recognized in recent years as a design issue for avionics equipment and systems. To ensure a system meets all its safety and reliability requirements, SEE induced upsets and potential system failures need to be considered, including testing of the components and systems in a neutron beam. Testing of ICs and systems for use in radiation environments requires the utilization of highly advanced laboratory facilities that can run evaluations on microcircuits for the effects of radiation. This paper provides a background of the atmospheric radiation phenomenon and the resulting single event effects, including single event upset (SEU) and latch up conditions. A study investigating requirements for future single event effect irradiation test facilities and developing options at the Spallation Neutron Source (SNS) is summarized. The relatively new SNS with its 1.0 GeV proton beam, typical operation of 5000 h per year, expertise in spallation neutron sources, user program infrastructure, and decades of useful life ahead is well suited for hosting a world-class SEE test facility in North America. Emphasis was put on testing of large avionics systems while still providing tunable high flux irradiation conditions for component tests. Makers of ground-based systems would also be served well by these facilities. Three options are described; the most capable, flexible, and highest-test-capacity option is a new stand-alone target station using about one kW of proton beam power on a gas-cooled tungsten target, with dual test enclosures. Less expensive options are also described.

  18. A one-dimensional transient model of a single-stage, downward-firing entrained-flow gasifier

    SciTech Connect

    Kasule, J.; Turton, R.; Bhattacharyya, D.; Zitney, S.

    2012-01-01

    The integrated gasification combined cycle (IGCC) technology has emerged as an attractive alternative to conventional coal-fired power plant technology due to its higher efficiency and cleaner environmental performance especially with the option of CO{sub 2} capture and sequestration. The core unit of this technology is the gasifier whose optimal performance must be understood for efficient operation of IGCC power plants. This need has led a number of researchers to develop gasifier models of varying complexities. Whereas high-fidelity CFD models can accurately predict most key aspects of gasifier performance, they are computationally expensive and typically take hours to days to execute on high-performance computers. Therefore, faster one-dimensional (1D) partial differential equation (PDE)-based models are required for use in dynamic simulation studies, control system analysis, and training applications. A number of 1D gasifier models can be found in the literature, but most are steady-state and have limited application in the practical operation of the gasifier. As a result, 1D PDE-based dynamic models are needed to further study and predict gasifier performance under a wide variety of process conditions and disturbances. In the present study, a 1D transient model of a single-stage downward flow GE/Texaco-type gasifier has been developed. The model comprises mass, momentum and energy balances for the gas and solid phases. The model considers the initial gasification processes of water evaporation and coal devolatilization. In addition, the key heterogeneous and homogeneous chemical reactions have been modeled. The resulting time-dependent PDE model is solved using the well-known method of lines approach in Aspen Custom Modeler®, whereby the PDEs are discretized in the spatial domain and the resulting differential algebraic equations (DAEs) are then solved to obtain the transient response. The transient response of various gasifier performance parameters to certain disturbances commonly encountered in the real world operation of commercial IGCC plants will be presented. These disturbances include ramp and step changes in input variables such as coal flow rate, oxygen-to-coal ratio and water-to-coal ratio, among others. Comparison of gasifier model predictions to available dynamic data will also be discussed.

  19. Visible Persistence of Single-Transient Random Dot Patterns: Spatial Parameters Affect the Duration of Fading Percepts.

    PubMed

    Bruchmann, Maximilian; Thaler, Kathrin; Vorberg, Dirk

    2015-01-01

    Visible persistence refers to the continuation of visual perception after the physical termination of a stimulus. We studied an extreme case of visible persistence by presenting two matrices of randomly distributed black and white pixels in succession. On the transition from one matrix to the second, the luminance polarity of all pixels within a disk- or annulus-shaped area reversed, physically creating a single second-order transient signal. This transient signal produces the percept of a disk or an annulus with an abrupt onset and a gradual offset. To study the nature of this fading percept we varied spatial parameters, such as the inner and the outer diameter of annuli (Experiment I) and the radius and eccentricity of disks (Experiment III), and measured the duration of visible persistence by having subjects adjust the synchrony of the onset of a reference stimulus with the onset or the offset of the fading percept. We validated this method by comparing two modalities of the reference stimuli (Experiment I) and by comparing the judgments of fading percepts with the judgments of stimuli that actually fade in luminance contrast (Experiment II). The results show that (i) irrespective of the reference modality, participants are able to precisely judge the on- and the offsets of the fading percepts, (ii) auditory reference stimuli lead to higher visible persistence durations than visual ones, (iii) visible persistence duration increases with the thickness of annuli and the diameter of disks, but decreases with the diameter of annuli, irrespective of stimulus eccentricity. These effects cannot be explained by stimulus energy, which suggests that more complex processing mechanisms are involved. Seemingly contradictory effects of disk and annulus diameter can be unified by assuming an abstract filling-in mechanism that speeds up with the strength of the edge signal and takes more time the larger the stimulus area is. PMID:26348616

  20. Visible Persistence of Single-Transient Random Dot Patterns: Spatial Parameters Affect the Duration of Fading Percepts

    PubMed Central

    Bruchmann, Maximilian; Thaler, Kathrin; Vorberg, Dirk

    2015-01-01

    Visible persistence refers to the continuation of visual perception after the physical termination of a stimulus. We studied an extreme case of visible persistence by presenting two matrices of randomly distributed black and white pixels in succession. On the transition from one matrix to the second, the luminance polarity of all pixels within a disk- or annulus-shaped area reversed, physically creating a single second-order transient signal. This transient signal produces the percept of a disk or an annulus with an abrupt onset and a gradual offset. To study the nature of this fading percept we varied spatial parameters, such as the inner and the outer diameter of annuli (Experiment I) and the radius and eccentricity of disks (Experiment III), and measured the duration of visible persistence by having subjects adjust the synchrony of the onset of a reference stimulus with the onset or the offset of the fading percept. We validated this method by comparing two modalities of the reference stimuli (Experiment I) and by comparing the judgments of fading percepts with the judgments of stimuli that actually fade in luminance contrast (Experiment II). The results show that (i) irrespective of the reference modality, participants are able to precisely judge the on- and the offsets of the fading percepts, (ii) auditory reference stimuli lead to higher visible persistence durations than visual ones, (iii) visible persistence duration increases with the thickness of annuli and the diameter of disks, but decreases with the diameter of annuli, irrespective of stimulus eccentricity. These effects cannot be explained by stimulus energy, which suggests that more complex processing mechanisms are involved. Seemingly contradictory effects of disk and annulus diameter can be unified by assuming an abstract filling-in mechanism that speeds up with the strength of the edge signal and takes more time the larger the stimulus area is. PMID:26348616

  1. Solution-processed single-walled carbon nanotube field effect transistors and bootstrapped inverters for disintegratable, transient electronics

    SciTech Connect

    Jin, Sung Hun E-mail: jhl@snu.ac.kr Shin, Jongmin; Cho, In-Tak; Lee, Jong-Ho E-mail: jhl@snu.ac.kr; Han, Sang Youn; Lee, Dong Joon; Lee, Chi Hwan; Rogers, John A. E-mail: jhl@snu.ac.kr

    2014-07-07

    This paper presents materials, device designs, and physical/electrical characteristics of a form of nanotube electronics that is physically transient, in the sense that all constituent elements dissolve and/or disperse upon immersion into water. Studies of contact effects illustrate the ability to use water soluble metals such as magnesium for source/drain contacts in nanotube based field effect transistors. High mobilities and on/off ratios in transistors that use molybdenum, silicon nitride, and silicon oxide enable full swing characteristics for inverters at low voltages (∼5 V) and with high gains (∼30). Dissolution/disintegration tests of such systems on water soluble sheets of polyvinyl alcohol demonstrate physical transience within 30 min.

  2. Solution-processed single-walled carbon nanotube field effect transistors and bootstrapped inverters for disintegratable, transient electronics

    NASA Astrophysics Data System (ADS)

    Jin, Sung Hun; Shin, Jongmin; Cho, In-Tak; Han, Sang Youn; Lee, Dong Joon; Lee, Chi Hwan; Lee, Jong-Ho; Rogers, John A.

    2014-07-01

    This paper presents materials, device designs, and physical/electrical characteristics of a form of nanotube electronics that is physically transient, in the sense that all constituent elements dissolve and/or disperse upon immersion into water. Studies of contact effects illustrate the ability to use water soluble metals such as magnesium for source/drain contacts in nanotube based field effect transistors. High mobilities and on/off ratios in transistors that use molybdenum, silicon nitride, and silicon oxide enable full swing characteristics for inverters at low voltages (˜5 V) and with high gains (˜30). Dissolution/disintegration tests of such systems on water soluble sheets of polyvinyl alcohol demonstrate physical transience within 30 min.

  3. Transient and Steady-state Tests of the Space Power Research Engine with Resistive and Motor Loads

    NASA Technical Reports Server (NTRS)

    Rauch, Jeffrey S.; Kankam, M. David

    1995-01-01

    The NASA Lewis Research Center (LeRC) has been testing free-piston Stirling engine/linear alternators (FPSE/LA) to develop advanced power convertors for space-based electrical power generation. Tests reported herein were performed to evaluate the interaction and transient behavior of FPSE/LA-based power systems with typical user loads. Both resistive and small induction motor loads were tested with the space power research engine (SPRE) power system. Tests showed that the control system could maintain constant long term voltage and stable periodic operation over a large range of engine operating parameters and loads. Modest resistive load changes were shown to cause relatively large voltage and, therefore, piston and displacer amplitude excursions. Starting a typical small induction motor was shown to cause large and, in some cases, deleterious voltage transients. The tests identified the need for more effective controls, if FPSE/LAs are to be used for stand-alone power systems. The tests also generated a large body of transient dynamic data useful for analysis code validation.

  4. Sequential hydraulic tests for transient and highly permeable unconfined aquifer systems - model development and field-scale implementation

    NASA Astrophysics Data System (ADS)

    Ni, C.-F.; Huang, Y.-J.; Dong, J.-J.; Yeh, T.-C. J.

    2015-12-01

    The transient hydraulic tomography survey (THTS) is a conceptually improved technique that efficiently estimates detailed variations in aquifer parameters. Based on the concept of the THTS, we developed a geostatistical inverse model to characterize saturated hydraulic conductivity (K) and the specific yield (Sy) in transient and unconfined aquifer systems. In this study, a synthetic example was first used to assess the accuracy of the developed inverse model. Multiple random K and Sy realizations with different variances of natural logarithm of K (lnK) were generated and systematically compared to evaluate the effects of joint inversion on K estimations. The model was implemented in field-scale, cross-hole injection tests in a shallow and highly permeable unconfined aquifer near the middle reaches of the Wu River in central Taiwan. To assess the effect of constant head boundary conditions on the estimation results, two additional modeling domains were evaluated on the basis of the same field data from the injection tests. The results of the synthetic example showed that the proposed inverse model can effectively reproduce the predefined K patterns and magnitudes. However, slightly less detail was obtained for the Sy field based on the sampling data from sequential transient hydraulic stresses. The joint inversion by using transient head observations could slightly decrease the accuracy of K estimations. The model implementation for field-scale injection tests showed that the model can estimate K and Sy fields with detailed spatial variations. Estimation results showed a relatively homogeneous aquifer for the tested well field. Results based on the three modeling domains showed similar patterns and magnitudes of K and Sy near the well locations. These results indicated that the THTS is relatively insensitive to artificially drawn boundary conditions even under transient conditions.

  5. System level latchup mitigation for single event and transient radiation effects on electronics

    DOEpatents

    Kimbrough, Joseph Robert; Colella, Nicholas John

    1997-01-01

    A "blink" technique, analogous to a person blinking at a flash of bright light, is provided for mitigating the effects of single event current latchup and prompt pulse destructive radiation on a micro-electronic circuit. The system includes event detection circuitry, power dump logic circuitry, and energy limiting measures with autonomous recovery. The event detection circuitry includes ionizing radiation pulse detection means for detecting a pulse of ionizing radiation and for providing at an output terminal thereof a detection signal indicative of the detection of a pulse of ionizing radiation. The current sensing circuitry is coupled to the power bus for determining an occurrence of excess current through the power bus caused by ionizing radiation or by ion-induced destructive latchup of a semiconductor device. The power dump circuitry includes power dump logic circuitry having a first input terminal connected to the output terminal of the ionizing radiation pulse detection circuitry and having a second input terminal connected to the output terminal of the current sensing circuitry. The power dump logic circuitry provides an output signal to the input terminal of the circuitry for opening the power bus and the circuitry for shorting the power bus to a ground potential to remove power from the power bus. The energy limiting circuitry with autonomous recovery includes circuitry for opening the power bus and circuitry for shorting the power bus to a ground potential. The circuitry for opening the power bus and circuitry for shorting the power bus to a ground potential includes a series FET and a shunt FET. The invention provides for self-contained sensing for latchup, first removal of power to protect latched components, and autonomous recovery to enable transparent operation of other system elements.

  6. System level latchup mitigation for single event and transient radiation effects on electronics

    DOEpatents

    Kimbrough, J.R.; Colella, N.J.

    1997-09-30

    A ``blink`` technique, analogous to a person blinking at a flash of bright light, is provided for mitigating the effects of single event current latchup and prompt pulse destructive radiation on a micro-electronic circuit. The system includes event detection circuitry, power dump logic circuitry, and energy limiting measures with autonomous recovery. The event detection circuitry includes ionizing radiation pulse detection means for detecting a pulse of ionizing radiation and for providing at an output terminal thereof a detection signal indicative of the detection of a pulse of ionizing radiation. The current sensing circuitry is coupled to the power bus for determining an occurrence of excess current through the power bus caused by ionizing radiation or by ion-induced destructive latchup of a semiconductor device. The power dump circuitry includes power dump logic circuitry having a first input terminal connected to the output terminal of the ionizing radiation pulse detection circuitry and having a second input terminal connected to the output terminal of the current sensing circuitry. The power dump logic circuitry provides an output signal to the input terminal of the circuitry for opening the power bus and the circuitry for shorting the power bus to a ground potential to remove power from the power bus. The energy limiting circuitry with autonomous recovery includes circuitry for opening the power bus and circuitry for shorting the power bus to a ground potential. The circuitry for opening the power bus and circuitry for shorting the power bus to a ground potential includes a series FET and a shunt FET. The invention provides for self-contained sensing for latchup, first removal of power to protect latched components, and autonomous recovery to enable transparent operation of other system elements. 18 figs.

  7. System level latchup mitigation for single event and transient radiation effects on electronics

    SciTech Connect

    Kimbrough, J.R.; Colella, N.J.

    1994-12-31

    A `blink` technique, analogous to a person blinking at a flash of bright light, is provided for mitigating the effects of single event current latchup and prompt pulse destructive radiation on a micro-electronic circuit. The system includes event detection means, power dump logic means, and energy limiting measures with autonomous recovery. The event detection means includes ionizing radiation pulse detection means for detecting a pulse of ionizing radiation and for providing at an output terminal thereof a detection signal indicative of the detection of a pulse of ionizing radiation or by ion-induced destructive latchup of a semiconductor device. The current sensing means is coupled to the power bus for determining an occurrence of excess current through the power bus caused by ionizing radiation. The power dump means includes power dump logic means having a first input terminal connected to the output terminal of the ionizing radiation pulse detection means and having a second input terminal connected to the output terminal of the current sensing means. The power dump logic means provides an output signal to the input terminal of the means for opening the power bus and the means for shorting the power bus to a ground potential to remove power from the power bus. The energy limiting mean with autonomous recovery includes means for opening the power bus and means for shorting the power bus to a ground potential. The means for opening the power bus and means for shorting the power bus to a ground potential includes a series FET and a shunt FET. The invention provides for self-contained sensing for latchup, first removal of power to protect latched components, and autonomous recovery to enable transparent operation of other system elements.

  8. Comparative research on “high currents” induced by single event latch-up and transient-induced latch-up

    NASA Astrophysics Data System (ADS)

    Chen, Rui; Han, Jian-Wei; Zheng, Han-Sheng; Yu, Yong-Tao; Shangguang, Shi-Peng; Feng, Guo-Qiang; Ma, Ying-Qi

    2015-04-01

    By using the pulsed laser single event effect facility and electro-static discharge (ESD) test system, the characteristics of the “high current”, relation with external stimulus and relevance to impacted modes of single event latch-up (SEL) and transient-induced latch-up (TLU) are studied, respectively, for a 12-bit complementary metal-oxide semiconductor (CMOS) analog-to-digital converter. Furthermore, the sameness and difference in physical mechanism between “high current” induced by SEL and that by TLU are disclosed in this paper. The results show that the minority carrier diffusion in the PNPN structure of the CMOS device which initiates the active parasitic NPN and PNP transistors is the common reason for the “high current” induced by SEL and for that by TLU. However, for SEL, the minority carrier diffusion is induced by the ionizing radiation, and an underdamped sinusoidal voltage on the supply node (the ground node) is the cause of the minority carrier diffusion for TLU. Project supported by the National Natural Science Foundation of China (Grant No. 41304148).

  9. 49 CFR 238.311 - Single car test.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Director of the Federal Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51. You may obtain a... Requirements for Tier I Passenger Equipment § 238.311 Single car test. (a) Except for self-propelled passenger...; (3) Piston assembly; (4) Vent valve; (5) Quick service valve; (6) Brake cylinder release valve;...

  10. Single-Antigen Serological Testing for Bovine Tuberculosis

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Antibody responses are useful indicators of Mycobacterium bovis infection of cattle. Tests for serological responses often use panels of multiple M. bovis antigens as detection probes. This is recommended because responses to single antigens may be too variable for consistent diagnosis. However, the...

  11. GPI-anchored single chain Fv - an effective way to capture transiently-exposed neutralization epitopes on HIV-1 envelope spike

    PubMed Central

    2010-01-01

    Background Identification of broad neutralization epitopes in HIV-1 envelope spikes is paramount for HIV-1 vaccine development. A few broad neutralization epitopes identified so far are present on the surface of native HIV-1 envelope spikes whose recognition by antibodies does not depend on conformational changes of the envelope spikes. However, HIV-1 envelope spikes also contain transiently-exposed neutralization epitopes, which are more difficult to identify. Results In this study, we constructed single chain Fvs (scFvs) derived from seven human monoclonal antibodies and genetically linked them with or without a glycosyl-phosphatidylinositol (GPI) attachment signal. We show that with a GPI attachment signal the scFvs are targeted to lipid rafts of plasma membranes. In addition, we demonstrate that four of the GPI-anchored scFvs, but not their secreted counterparts, neutralize HIV-1 with various degrees of breadth and potency. Among them, GPI-anchored scFv (X5) exhibits extremely potent and broad neutralization activity against multiple clades of HIV-1 strains tested. Moreover, we show that GPI-anchored scFv (4E10) also exhibited more potent neutralization activity than its secretory counterpart. Finally, we demonstrate that expression of GPI-anchored scFv (X5) in the lipid raft of plasma membrane of human CD4+ T cells confers long-term resistance to HIV-1 infection, HIV-1 envelope-mediated cell-cell fusion, and the infection of HIV-1 captured and transferred by human DCs. Conclusions Thus GPI-anchored scFv could be used as a general and effective way to identify antibodies that react with transiently-exposed neutralization epitopes in envelope proteins of HIV-1 and other enveloped viruses. The GPI-anchored scFv (X5), because of its breadth and potency, should have a great potential to be developed into anti-viral agent for HIV-1 prevention and therapy. PMID:20923574

  12. New transient modeling of an irreversible single-electron box and its application to a majority gate

    NASA Astrophysics Data System (ADS)

    Sharifi, M. J.; Jamshidnezhad, K.

    2013-02-01

    This paper introduces an equivalent circuit model for an irreversible single-electron box (SEB) in HSPICE. This model is based on the orthodox theory and the solution to the master equation in the time domain. Using this model, we study the behavior of the device at low-frequencies and its hysteresis characteristic, and we compare the results with those of simulation of nano-structures (SIMON), considered as a reference. We observe that the results in the steady-state limit obtained from our model are completely identical to those of SIMON. In addition, the behaviors of the device at high-frequencies are calculated using the proposed model. To verify the results, they are compared with analytical solutions for a square-pulse input signal. We see that our circuit model also gives accurate results for transient calculations. As an applicable example, the proposed circuit model is applied to an irreversible SEB-based majority gate, and the time-dependent outputs are calculated.

  13. Single Event Effect microchip testing at the Texas A&M University Cyclotron Institute

    NASA Astrophysics Data System (ADS)

    Clark, Henry; Yennello, Sherry; Texas A&M University-Cyclotron Institute Team

    2015-10-01

    A Single Event Effect (SEE) is caused by a single, energetic particle that deposits a sufficient amount of charge in a device as it transverses it and upsets its normal operation. Soft errors are non-destructive and normally appear as transient pulses in logic or support circuitry, or as bit flips in memory cells or registers. Hard errors usually result in a high operating current, above device specifications, and must be cleared by a power reset. Burnout errors are so destructive that the device becomes operationally dead. Spacecraft designers must be concerned with the causes of SEE's from protons and heavy ions since commercial devices are typically chosen reduce the parameters of power, weight, volume and cost but have increased functionality, which in turn are typically vulnerable to SEE. As a result all mission-critical devices must be tested. The TAMU K500 superconducting cyclotron has provided beams for space radiation testing since 1994. Starting at just 100 hours/year at inception, the demand has grown to 3000 hours/year. In recent years, most beam time has been for US defense system testing. Nearly 15% has been provided for foreign agencies from Europe and Asia. An overview of the testing facility and future plans will be presented.

  14. Instrumented Taylor anvil-on-rod impact tests for validating applicability of standard strength models to transient deformation states

    NASA Astrophysics Data System (ADS)

    Eakins, D. E.; Thadhani, N. N.

    2006-10-01

    Instrumented Taylor anvil-on-rod impact tests have been conducted on oxygen-free electronic copper to validate the accuracy of current strength models for predicting transient states during dynamic deformation events. The experiments coupled the use of high-speed digital photography to record the transient deformation states and laser interferometry to monitor the sample back (free surface) velocity as a measure of the elastic/plastic wave propagation through the sample length. Numerical continuum dynamics simulations of the impact and plastic wave propagation employing the Johnson-Cook [Proceedings of the Seventh International Symposium on Ballistics, 1983, The Netherlands (Am. Def. Prep. Assoc. (ADPA)), pp. 541-547], Zerilli-Armstrong [J. Appl. Phys. C1, 1816 (1987)], and Steinberg-Guinan [J. Appl. Phys. 51, 1498 (1980)] constitutive equations were used to generate transient deformation profiles and the free surface velocity traces. While these simulations showed good correlation with the measured free surface velocity traces and the final deformed sample shape, varying degrees of deviations were observed between the photographed and calculated specimen profiles at intermediate deformation states. The results illustrate the usefulness of the instrumented Taylor anvil-on-rod impact technique for validating constitutive equations that can describe the path-dependent deformation response and can therefore predict the transient and final deformation states.

  15. Transient Hypothyroidism after Radioiodine for Graves’ Disease: Challenges in Interpreting Thyroid Function Tests

    PubMed Central

    Sheehan, Michael T.; Doi, Suhail A.R.

    2016-01-01

    Graves’ disease is the most common cause of hyperthyroidism and is often managed with radioactive iodine (RAI) therapy. With current dosing schemes, the vast majority of patients develop permanent post-RAI hypothyroidism and are placed on life-long levothyroxine therapy. This hypothyroidism typically occurs within the first 3 to 6 months after RAI therapy is administered. Indeed, patients are typically told to expect life-long thyroid hormone replacement therapy to be required within this timeframe and many providers expect this post-RAI hypothyroidism to be complete and permanent. There is, however, a small subset of patients in whom a transient post-RAI hypothyroidism develops which, initially, presents exactly as the typical permanent hypothyroidism. In some cases the transient hypothyroidism leads to a period of euthyroidism of variable duration eventually progressing to permanent hypothyroidism. In others, persistent hyperthyroidism requires a second dose of RAI. Failure to appreciate and recognize the possibility of transient post-RAI hypothyroidism can delay optimal and appropriate treatment of the patient. We herein describe five cases of transient post-RAI hypothyroidism which highlight this unusual sequence of events. Increased awareness of this possible outcome after RAI for Graves’ disease will help in the timely management of patients. PMID:26864507

  16. Transient Hypothyroidism after Radioiodine for Graves' Disease: Challenges in Interpreting Thyroid Function Tests.

    PubMed

    Sheehan, Michael T; Doi, Suhail A R

    2016-03-01

    Graves' disease is the most common cause of hyperthyroidism and is often managed with radioactive iodine (RAI) therapy. With current dosing schemes, the vast majority of patients develop permanent post-RAI hypothyroidism and are placed on life-long levothyroxine therapy. This hypothyroidism typically occurs within the first 3 to 6 months after RAI therapy is administered. Indeed, patients are typically told to expect life-long thyroid hormone replacement therapy to be required within this timeframe and many providers expect this post-RAI hypothyroidism to be complete and permanent. There is, however, a small subset of patients in whom a transient post-RAI hypothyroidism develops which, initially, presents exactly as the typical permanent hypothyroidism. In some cases the transient hypothyroidism leads to a period of euthyroidism of variable duration eventually progressing to permanent hypothyroidism. In others, persistent hyperthyroidism requires a second dose of RAI. Failure to appreciate and recognize the possibility of transient post-RAI hypothyroidism can delay optimal and appropriate treatment of the patient. We herein describe five cases of transient post-RAI hypothyroidism which highlight this unusual sequence of events. Increased awareness of this possible outcome after RAI for Graves' disease will help in the timely management of patients. PMID:26864507

  17. Statistical properties of single-marker tests for rare variants.

    PubMed

    Bigdeli, T Bernard; Neale, Benjamin M; Neale, Michael C

    2014-06-01

    With the dramatic technological developments of genome-wide association single-nucleotide polymorphism (SNP) chips and next generation sequencing, human geneticists now have the ability to assay genetic variation at ever-rarer allele frequencies. To fully understand the impact of these rare variants on common, complex diseases, we must be able to accurately assess their statistical significance. However, it is well established that classical association tests are not appropriate for the analysis of low-frequency variation, giving spurious findings when observed counts are too few. To further our understanding of the asymptotic properties of traditional association tests, we conducted a range of simulations of a typical rare variant (~1%) under the null hypothesis and tested the allelic χ2, Cochran-Armitage trend, Wald, and Fisher's exact tests. We demonstrate that rare variation shows marked deviation from the expected distributional behavior for each test, with fewer minor alleles corresponding to a greater degree of test statistics deflation. The effect becomes more pronounced at progressively smaller α levels. We also show that the Wald test is particularly deflated at α levels consistent with genome-wide association significance, much more so than the other association tests considered. In general, these classical association tests are inappropriate for the analysis of variants for which the minor allele is observed fewer than 80 times, largely irrespective of sample size. PMID:24739319

  18. FOREVER ALONE? TESTING SINGLE ECCENTRIC PLANETARY SYSTEMS FOR MULTIPLE COMPANIONS

    SciTech Connect

    Wittenmyer, Robert A.; Horner, Jonathan; Tinney, C. G.; Bailey, J.; Salter, G. S.; Wright, D.; Wang Songhu; Zhou Jilin; Butler, R. P.; Jones, H. R. A.; O'Toole, S. J.; Carter, B. D.

    2013-09-15

    Determining the orbital eccentricity of an extrasolar planet is critically important for understanding the system's dynamical environment and history. However, eccentricity is often poorly determined or entirely mischaracterized due to poor observational sampling, low signal-to-noise, and/or degeneracies with other planetary signals. Some systems previously thought to contain a single, moderate-eccentricity planet have been shown, after further monitoring, to host two planets on nearly circular orbits. We investigate published apparent single-planet systems to see if the available data can be better fit by two lower-eccentricity planets. We identify nine promising candidate systems and perform detailed dynamical tests to confirm the stability of the potential new multiple-planet systems. Finally, we compare the expected orbits of the single- and double-planet scenarios to better inform future observations of these interesting systems.

  19. Test methods for single event upset/latch-up

    NASA Astrophysics Data System (ADS)

    Harboe-Sorensen, R.

    1994-01-01

    The best way of assessing semiconductor susceptibility to Single Event Phenomena (SEP) would be to measure their response while operating in the actual space environment. However, this a very expensive way to characterise semiconductors and has only been carried out on a very limited number of device types. Generally, the space radiation environment has been simulated in the laboratory and semiconductor characterisation has been carried out using differenct test systems and operating conditions. Where orbital upset data and ground simulation data exist, large variations were often found between observed and predicted upset rates. Better Single Event Upset (SEU) data and device technology information would help improve the prediction process. Here we concentrate on the ground testing itself and only touch on the prediction versus observation of a few devices. Heavy ion and proton test facilities used by ESA will be described together with test techniques and test procedures. Examples of Californium-252, recent heavy ion and proton SEU data on memories and microprocesors will also be presented.

  20. Single-qubit tests of Bell-like inequalities

    SciTech Connect

    Zela, F. de

    2007-10-15

    This paper discusses some tests of Bell-like inequalities not requiring entangled states. The proposed tests are based on consecutive measurements on a single qubit. Available hidden-variable models for a single qubit [see, e.g., J. S. Bell, Rev. Mod. Phys. 38, 447 (1966)] reproduce the predictions of quantum mechanics and hence violate the Bell-like inequalities addressed in this paper. It is shown how this fact is connected with the state 'collapse' and with its random nature. Thus, it becomes possible to test truly realistic and deterministic hidden-variable models. In this way, it can be shown that a hidden-variable model should entail at least one of the following features: (i) nonlocality, (ii) contextuality, or (iii) discontinuous measurement-dependent probability functions. The last two features are put to the test with the experiments proposed in this paper. A hidden-variable model that is noncontextual and deterministic would be at variance with some predictions of quantum mechanics. Furthermore, the proposed tests are more likely to be loophole-free, as compared to former ones.

  1. Global nuclear energy partnership fuels transient testing at the Sandia National Laboratories nuclear facilities : planning and facility infrastructure options.

    SciTech Connect

    Kelly, John E.; Wright, Steven Alan; Tikare, Veena; MacLean, Heather J.; Parma, Edward J., Jr.; Peters, Curtis D.; Vernon, Milton E.; Pickard, Paul S.

    2007-10-01

    The Global Nuclear Energy Partnership fuels development program is currently developing metallic, oxide, and nitride fuel forms as candidate fuels for an Advanced Burner Reactor. The Advance Burner Reactor is being designed to fission actinides efficiently, thereby reducing the long-term storage requirements for spent fuel repositories. Small fuel samples are being fabricated and evaluated with different transuranic loadings and with extensive burnup using the Advanced Test Reactor. During the next several years, numerous fuel samples will be fabricated, evaluated, and tested, with the eventual goal of developing a transmuter fuel database that supports the down selection to the most suitable fuel type. To provide a comparative database of safety margins for the range of potential transmuter fuels, this report describes a plan to conduct a set of early transient tests in the Annular Core Research Reactor at Sandia National Laboratories. The Annular Core Research Reactor is uniquely qualified to perform these types of tests because of its wide range of operating capabilities and large dry central cavity which extents through the center of the core. The goal of the fuels testing program is to demonstrate that the design and fabrication processes are of sufficient quality that the fuel will not fail at its design limit--up to a specified burnup, power density, and operating temperature. Transient testing is required to determine the fuel pin failure thresholds and to demonstrate that adequate fuel failure margins exist during the postulated design basis accidents.

  2. Analysis of BCL transient ECC-bypass test with TRAC-PD2/MOD1 code. [PWR

    SciTech Connect

    Slovik, G.; Saha, P.

    1982-01-01

    As part of the independent assessment of the TRAC-PD2/MOD1 code, a calculation for the Battelle Columbus Laboratories (BCL) transient Emergency Core Cooling (ECC) bypass test was performed. The purpose of this calculation was to assess the code's capability to predict the lower plenum refill rate after the initiation of ECC water injection during a postulated large break LOCA in a PWR system. BCL conducted several ECC bypass tests in their 2/15th-scale model of a typical pressurized water reactor vessel.

  3. Quick Look Report for Semiscale MOD-2C Test S-FS-6. [Simulating PWR transient from SG line break

    SciTech Connect

    Boucher, T.J.; Hall, D.G.

    1985-09-01

    Results of a preliminary analysis of the third test performed in the Semiscale MOD-2C Steam Generator Feedwater and Steam Line Break (FS) experiment series are presented. Test S-FS-6 simulated a pressurized water reactor transient initiated by a 100% break in a steam generator bottom feedwater line downstream of the check valve. With the exception of primary pressure, the initial conditions represented the initial conditions used for the C-E System 80 Final Safety Analysis Report (FSAR) Appendix 15B calculations. The transient included an initial 600s period in which only automatic plant protection systems responded to the initiating event. This period was followed by a series of operator actions necessary to stabilize the plant and a subsequent operator controlled natural circulation cooldown and depressurization with upper head void collapse method investigations. The test results provided a measured evaluation of the effectiveness of the automatic responses in minimizing primary system overpressurization and operator actions in stabilizing and recovering the plant. Test data also provided a basis for comparison with other tests in the series of the effects of break size on primary overpressurization and primary-to-secondary heat transfer.

  4. Coincident steam generator tube rupture and stuck-open safety relief valve carryover tests: MB-2 steam generator transient response test program

    SciTech Connect

    Garbett, K; Mendler, O J; Gardner, G C; Garnsey, R; Young, M Y

    1987-03-01

    In PWR steam generator tube rupture (SGTR) faults, a direct pathway for the release of radioactive fission products can exist if there is a coincident stuck-open safety relief valve (SORV) or if the safety relief valve is cycled. In addition to the release of fission products from the bulk steam generator water by moisture carryover, there exists the possibility that some primary coolant may be released without having first mixed with the bulk water - a process called primary coolant bypassing. The MB-2 Phase II test program was designed specifically to identify the processes for droplet carryover during SGTR faults and to provide data of sufficient accuracy for use in developing physical models and computer codes to describe activity release. The test program consisted of sixteen separate tests designed to cover a range of steady-state and transient fault conditions. These included a full SGTR/SORV transient simulation, two SGTR overfill tests, ten steady-state SGTR tests at water levels ranging from very low levels in the bundle up to those when the dryer was flooded, and three moisture carryover tests without SGTR. In these tests the influence of break location and the effect of bypassing the dryer were also studied. In a final test the behavior with respect to aerosol particles in a dry steam generator, appropriate to a severe accident fault, was investigated.

  5. Constitutive modeling of superalloy single crystals with verification testing

    NASA Technical Reports Server (NTRS)

    Jordan, Eric; Walker, Kevin P.

    1985-01-01

    The goal is the development of constitutive equations to describe the elevated temperature stress-strain behavior of single crystal turbine blade alloys. The program includes both the development of a suitable model and verification of the model through elevated temperature-torsion testing. A constitutive model is derived from postulated constitutive behavior on individual crystallographic slip systems. The behavior of the entire single crystal is then arrived at by summing up the slip on all the operative crystallographic slip systems. This type of formulation has a number of important advantages, including the prediction orientation dependence and the ability to directly represent the constitutive behavior in terms which metallurgists use in describing the micromechanisms. Here, the model is briefly described, followed by the experimental set-up and some experimental findings to date.

  6. IGR J17354-3255 as bench test for investigation of ?-ray emission from Supergiant Fast X-ray Transients

    NASA Astrophysics Data System (ADS)

    Sguera, V.

    2013-06-01

    Among the different types of sources shining in the high energy sky, gamma-ray binaries are rapidly becoming the subject of major interest. In fact, in the last few years a number of High Mass X-ray Binaries (HMXBs) have been firmly detected from MeV to TeV energies, providing secure evidences that particles can be efficiently accelerated up to very high energies in such galactic systems. Similarly to this general and emerging class of gamma-ray binaries, in principle Supergiant Fast X-ray Transients (SFXTs) have all the "ingredients" to be transient high energy emitters. In this context, the SFXT IGR J17354-3255 is a good bench test and we present intriguing hints likely suggesting that it is a transient gamma-ray source flaring on short timescales. If fully confirmed by further studies, the implications stemming are huge, both theoretically and observationally, and would add a further extreme characteristic to the already extreme class of SFXTs.

  7. Cultural Resource Investigations for the Resumption of Transient Testing of Nuclear Fuels and Material at the Idaho National Laboratory

    SciTech Connect

    Brenda R. Pace; Julie B. Williams

    2013-11-01

    The U. S. Department of Energy (DOE) has a need to test nuclear fuels under conditions that subject them to short bursts of intense, high-power radiation called ‘transient testing’ in order to gain important information necessary for licensing new nuclear fuels for use in U.S. nuclear power plants, for developing information to help improve current nuclear power plant performance and sustainability, for improving the affordability of new generation reactors, for developing recyclable nuclear fuels, and for developing fuels that inhibit any repurposing into nuclear weapons. To meet this mission need, DOE is considering alternatives for re-use and modification of existing nuclear reactor facilities to support a renewed transient testing program. One alternative under consideration involves restarting the Transient Reactor Test (TREAT) reactor located at the Materials and Fuels Complex (MFC) on the Idaho National Laboratory (INL) site in southeastern Idaho. This report summarizes cultural resource investigations conducted by the INL Cultural Resource Management Office in 2013 to support environmental review of activities associated with restarting the TREAT reactor at the INL. These investigations were completed in order to identify and assess the significance of cultural resources within areas of potential effect associated with the proposed action and determine if the TREAT alternative would affect significant cultural resources or historic properties that are eligible for nomination to the National Register of Historic Places. No archaeological resources were identified in the direct area of potential effects for the project, but four of the buildings proposed for modifications are evaluated as historic properties, potentially eligible for nomination to the National Register of Historic Places. This includes the TREAT reactor (building #), control building (building #), guardhouse (building #), and warehouse (building #). The proposed re-use of these historic properties is consistent with original missions related to nuclear reactor testing and is expected to result in no adverse effects to their historic significance. Cultural resource investigations also involved communication with representatives from the Shoshone-Bannock Tribes to characterize cultural resources of potential tribal concern. This report provides a summary of the cultural resources inventoried and assessed within the defined areas of potential effect for the resumption of transient testing at the INL. Based on these analyses, proposed activities would have no adverse effects on historic properties within the APEs that have been defined. Other archaeological resources and cultural resources of potential concern to the Shoshone-Bannock Tribes and others that are located near the APEs are also discussed with regard to potential indirect impacts. The report concludes with general recommendations for measures to reduce impacts to all identified resources.

  8. Transient Plume Model Testing Using LADEE Spacecraft Attitude Control System Operations

    NASA Technical Reports Server (NTRS)

    Woronowicz, Michael

    2011-01-01

    We have learned it is conceivable that the Neutral Mass Spectrometer on board the Lunarr Atmosphere Dust Environment Explorer (LADEE) could measure gases from surface-reflected Attitude Control System (ACS) thruster plume. At minimum altitude, the measurement would be maximized, and gravitational influence minimized ("short" time-of-flight (TOF) situation) Could use to verify aspects of thruster plume modeling Model the transient disturbance to NMS measurements due to ACS gases reflected from lunar surface Observe evolution of various model characteristics as measured by NMS Species magnitudes, TOF measurements, angular distribution, species separation effects

  9. Engineering test results for the Moog Single Line Disconnect

    NASA Technical Reports Server (NTRS)

    Glubke, Scott E.

    1990-01-01

    New and innovative types of disconnects will be required to service, resupply, and maintain future spacecraft subsystems. Efficiently maintaining orbiting scientific instruments, spacecraft support systems, and a manned space station over a long period of time will require the periodic replenishment of consumables and the replacement of components. To accomplish these tasks, the fluid disconnect must be designed to allow the connection and separation of fluid lines and components with minimal hazard to crew and equipment. The capability to simply connect a refueling line or to easily replace a failed component greatly extends the life of a space based fluid system. A test program was initiated to evaluate the Moog Single Line Disconnect. The objective of the test program was to demonstrate the operational characteristics of the disconnect and to verify compliance with current safety regulations. The results of the program are summarized in the referenced document.

  10. Design, fabrication and testing of single spoke resonators at Fermilab

    SciTech Connect

    Ristori, L.; Apollinari, G.; Borissov, E.; Gonin, I.V.; Khabiboulline, T.N.; Mukherjee, A.; Nicol, T.H.; Ozelis, J.; Pischalnikov, Y.; Sergatskov, D.A.; Wagner, R.; /Fermilab

    2009-09-01

    The Fermilab High Intensity Neutrino Source (HINS) linac R&D program is building a pulsed 30 MeV superconducting H- linac. The linac incorporates superconducting solenoids, high power RF vector modulators and superconducting spoke-type accelerating cavities starting at 10 MeV. This will be the first application and demonstration of any of these technologies in a low-energy, high-intensity proton/H- linac. The HINS effort is relevant to a high intensity, superconducting H- linac that might serve the next generation of neutrino physics and muon storage ring/collider experiments. In this paper we present the RF design, the mechanical design, the fabrication, the chemistry and testing of the first two SSR1 (Single Spoke Resonator type-1) prototype cavities that were built. These cavities operate at 325 MHz with {beta} = 0.21. The design and testing of the input coupler and the tuning mechanism are also discussed.

  11. Single-pass rub testing of abradable seal materials

    NASA Technical Reports Server (NTRS)

    Kennedy, F. E.; Hine, N. P.

    1981-01-01

    A pendulum-type test device has been built for use in studying rubs between a turbine or compressor blade tip or labyrinth seal knife edge and specimens of abradable gas path seal materials. The device allows measurement of the rub energy dissipated in a single wear event, along with friction and normal forces and wear. Subsequent rubs over the same surface can also be monitored, with microscopic observation of the rub surface being possible after any of the passes. The device was used in tests of several potential abradable materials, ranging from porous to fully dense. It was shown that the rub energy dissipated in initial and subsequent passes is a fundamental parameter in the evaluation of material abradability. Rub energy was found to be influenced by such factors as: density and tensile (or yield) strength of the abradable material, prior densification or work hardening of the rub surface, and the sharpness of the leading edge of the blade tip.

  12. Implementation and Testing of the First Prompt Search for Gravitational Wave Transients with Electromagnetic Counterparts

    NASA Technical Reports Server (NTRS)

    Abadie, J.; Abbott, B. P.; Abbott, R.; Abbott, T. D.; Abernathy, M.; Accadia, T.; Acernese, F.; Adams, C.; Adhikari, R.; Affeldt, C.; Agathos, M.; Ajith, P.; Allen, B.; Allen, G. S.; Ceron, E. Amador; Amariutei, D.; Amin, R. S.; Anderson, S. B.; Anderson, W. G.; Araya, M. C.; Aston, S. M.; Astone, P.; Atkinson, D.; Aufmuth, P.; Blackburn, L.

    2012-01-01

    Aims. A transient astrophysical event observed in both gravitational wave (GW) and electromagnetic (EM) channels would yield rich scientific rewards. A first program initiating EM follow-ups to possible transient GW events has been developed and exercised by the LIGO and Virgo community in association with several partners. In this paper, we describe and evaluate the methods used to promptly identify and localize GW event candidates and to request images of targeted sky locations. Methods. During two observing periods (Dec. 17, 2009 to Jan. 8, 2010 and Sep. 2 to Oct. 20, 2010), a low-latency analysis pipeline was used to identify GW event candidates and to reconstruct maps of possible sky locations. A catalog of nearby galaxies and MilkyWay globular clusters was used to select the most promising sky positions to be imaged, and this directional information was delivered to EM observatories with time lags of about thirty minutes. A Monte Carlo simulation has been used to evaluate the low-latency GW pipeline's ability to reconstruct source positions correctly. Results. For signals near the detection threshold, our low-latency algorithms often localized simulated GW burst signals to tens of square degrees, while neutron star/neutron star inspirals and neutron star/black hole inspirals were localized to a few hundred square degrees. Localization precision improves for moderately stronger signals. The correct sky location of signals well above threshold and originating from nearby galaxies may be observed with 50% or better probability with a few pointings of wide-field telescopes.

  13. Implementation and testing of the first prompt search for gravitational wave transients with electromagnetic counterparts

    NASA Astrophysics Data System (ADS)

    LIGO Scientific Collaboration; Virgo Collaboration; Abadie, J.; Abbott, B. P.; Abbott, R.; Abbott, T. D.; Abernathy, M.; Accadia, T.; Acernese, F.; Adams, C.; Adhikari, R.; Affeldt, C.; Ajith, P.; Allen, B.; Allen, G. S.; Amador Ceron, E.; Amariutei, D.; Amin, R. S.; Anderson, S. B.; Anderson, W. G.; Arai, K.; Arain, M. A.; Araya, M. C.; Aston, S. M.; Astone, P.; Atkinson, D.; Aufmuth, P.; Aulbert, C.; Aylott, B. E.; Babak, S.; Baker, P.; Ballardin, G.; Ballmer, S.; Barker, D.; Barone, F.; Barr, B.; Barriga, P.; Barsotti, L.; Barsuglia, M.; Barton, M. A.; Bartos, I.; Bassiri, R.; Bastarrika, M.; Basti, A.; Batch, J.; Bauchrowitz, J.; Bauer, Th. S.; Bebronne, M.; Behnke, B.; Beker, M. G.; Bell, A. S.; Belletoile, A.; Belopolski, I.; Benacquista, M.; Berliner, J. M.; Bertolini, A.; Betzwieser, J.; Beveridge, N.; Beyersdorf, P. T.; Bilenko, I. A.; Billingsley, G.; Birch, J.; Biswas, R.; Bitossi, M.; Bizouard, M. A.; Black, E.; Blackburn, J. K.; Blackburn, L.; Blair, D.; Bland, B.; Blom, M.; Bock, O.; Bodiya, T. P.; Bogan, C.; Bondarescu, R.; Bondu, F.; Bonelli, L.; Bonnand, R.; Bork, R.; Born, M.; Boschi, V.; Bose, S.; Bosi, L.; Bouhou, B.; Braccini, S.; Bradaschia, C.; Brady, P. R.; Braginsky, V. B.; Branchesi, M.; Brau, J. E.; Breyer, J.; Briant, T.; Bridges, D. O.; Brillet, A.; Brinkmann, M.; Brisson, V.; Britzger, M.; Brooks, A. F.; Brown, D. A.; Brummit, A.; Bulik, T.; Bulten, H. J.; Buonanno, A.; Burguet-Castell, J.; Burmeister, O.; Buskulic, D.; Buy, C.; Byer, R. L.; Cadonati, L.; Cagnoli, G.; Calloni, E.; Camp, J. B.; Campsie, P.; Cannizzo, J.; Cannon, K.; Canuel, B.; Cao, J.; Capano, C. D.; Carbognani, F.; Caride, S.; Caudill, S.; Cavaglià, M.; Cavalier, F.; Cavalieri, R.; Cella, G.; Cepeda, C.; Cesarin, E.; Chaibi, O.; Chalermsongsak, T.; Chalkley, E.; Charlton, P.; Chassande-Mottin, E.; Chelkowski, S.; Chen, Y.; Chincarini, A.; Chiummo, A.; Cho, H.; Christensen, N.; Chua, S. S. Y.; Chung, C. T. Y.; Chung, S.; Ciani, G.; Clara, F.; Clark, D. E.; Clark, J.; Clayton, J. H.; Cleva, F.; Coccia, E.; Cohadon, P.-F.; Colacino, C. N.; Colas, J.; Colla, A.; Colombini, M.; Conte, A.; Conte, R.; Cook, D.; Corbitt, T. R.; Cordier, M.; Cornish, N.; Corsi, A.; Costa, C. A.; Coughlin, M.; Coulon, J.-P.; Couvares, P.; Coward, D. M.; Coyne, D. C.; Creighton, J. D. E.; Creighton, T. D.; Cruise, A. M.; Cumming, A.; Cunningham, L.; Cuoco, E.; Cutler, R. M.; Dahl, K.; Danilishin, S. L.; Dannenberg, R.; D'Antonio, S.; Danzmann, K.; Dattilo, V.; Daudert, B.; Daveloza, H.; Davier, M.; Davies, G.; Daw, E. J.; Day, R.; Dayanga, T.; DeRosa, R.; Debra, D.; Debreczeni, G.; Degallaix, J.; Del Pozzo, W.; Del Prete, M.; Dent, T.; Dergachev, V.; Derosa, R.; Desalvo, R.; Dhillon, V.; Dhurandhar, S.; Di Fiore, L.; Di Lieto, A.; Di Palma, I.; De Paolo Emilio, M.; Di Virgilio, A.; Díaz, M.; Dietz, A.; Diguglielmo, J.; Donovan, F.; Dooley, K. L.; Dorsher, S.; Drago, M.; Drever, R. W. P.; Driggers, J. C.; Du, Z.; Dumas, J.-C.; Dwyer, S.; Eberle, T.; Edgar, M.; Edwards, M.; Effler, A.; Ehrens, P.; Endröczi, G.; Engel, R.; Etzel, T.; Evans, K.; Evans, M.; Evans, T.; Factourovich, M.; Fafone, V.; Fairhurst, S.; Fan, Y.; Farr, B. F.; Farr, W.; Fazi, D.; Fehrmann, H.; Feldbaum, D.; Ferrante, I.; Fidecaro, F.; Finn, L. S.; Fiori, I.; Fisher, R. P.; Flaminio, R.; Flanigan, M.; Foley, S.; Forsi, E.; Forte, L. A.; Fotopoulos, N.; Fournier, J.-D.; Franc, J.; Frasca, S.; Frasconi, F.; Frede, M.; Frei, M.; Frei, Z.; Freise, A.; Frey, R.; Fricke, T. T.; Fridriksson, J. K.; Friedrich, D.; Fritschel, P.; Frolov, V. V.; Fulda, P. J.; Fyffe, M.; Galimberti, M.; Gammaitoni, L.; Ganija, M. R.; Garcia, J.; Garofoli, J. A.; Garufi, F.; Gáspár, M. E.; Gemme, G.; Geng, R.; Genin, E.; Gennai, A.; Gergely, L. Á.; Ghosh, S.; Giaime, J. A.; Giampanis, S.; Giardina, K. D.; Giazotto, A.; Gill, C.; Goetz, E.; Goggin, L. M.; González, G.; Gorodetsky, M. L.; Goßler, S.; Gouaty, R.; Graef, C.; Granata, M.; Grant, A.; Gras, S.; Gray, C.; Gray, N.; Greenhalgh, R. J. S.; Gretarsson, A. M.; Greverie, C.; Grosso, R.; Grote, H.; Grunewald, S.; Guidi, G. M.; Guido, C.; Gupta, R.; Gustafson, E. K.; Gustafson, R.; Ha, T.; Hage, B.; Hallam, J. M.; Hammer, D.; Hammond, G.; Hanks, J.; Hanna, C.; Hanson, J.; Harms, J.; Harry, G. M.; Harry, I. W.; Harstad, E. D.; Hartman, M. T.; Haughian, K.; Hayama, K.; Hayau, J.-F.; Hayler, T.; Heefner, J.; Heidmann, A.; Heintze, M. C.; Heitmann, H.; Hello, P.; Hendry, M. A.; Heng, I. S.; Heptonstall, A. W.; Herrera, V.; Hewitson, M.; Hild, S.; Hoak, D.; Hodge, K. A.; Holt, K.; Homan, J.; Hong, T.; Hooper, S.; Hosken, D. J.; Hough, J.; Howell, E. J.; Hughey, B.; Husa, S.; Huttner, S. H.; Huynh-Dinh, T.; Ingram, D. R.; Inta, R.; Isogai, T.; Ivanov, A.; Izumi, K.; Jacobson, M.; Jang, H.; Jaranowski, P.; Johnson, W. W.; Jones, D. I.; Jones, G.; Jones, R.; Ju, L.; Kalmus, P.; Kalogera, V.; Kamaretsos, I.; Kandhasamy, S.; Kang, G.; Kanner, J. B.; Katsavounidis, E.; Katzman, W.; Kaufer, H.; Kawabe, K.; Kawamura, S.; Kawazoe, F.; Kells, W.; Keppel, D. G.; Keresztes, Z.; Khalaidovski, A.; Khalili, F. Y.; Khazanov, E. A.; Kim, B.; Kim, C.; Kim, D.; Kim, H.; Kim, K.; Kim, N.; Kim, Y.-M.; King, P. J.; Kinsey, M.; Kinzel, D. L.; Kissel, J. S.; Klimenko, S.; Kokeyama, K.; Kondrashov, V.; Kopparapu, R.; Koranda, S.; Korth, W. Z.; Kowalska, I.; Kozak, D.; Kringel, V.; Krishnamurthy, S.; Krishnan, B.; Krâ´Olak, A.; Kuehn, G.; Kumar, R.; Kwee, P.; Laas-Bourez, M.; Lam, P. K.; Landry, M.; Lang, M.; Lantz, B.; Lastzka, N.; Lawrie, C.; Lazzarini, A.; Leaci, P.; Lee, C. H.; Lee, H. M.; Leindecker, N.; Leong, J. R.; Leonor, I.; Leroy, N.; Letendre, N.; Li, J.; Li, T. G. F.; Liguori, N.; Lindquist, P. E.; Lockerbie, N. A.; Lodhia, D.; Lorenzini, M.; Loriette, V.; Lormand, M.; Losurdo, G.; Luan, J.; Lubinski, M.; Lück, H.; Lundgren, A. P.; MacDonald, E.; Machenschalk, B.; Macinnis, M.; MacLeod, D. M.; Mageswaran, M.; Mailand, K.; Majorana, E.; Maksimovic, I.; Man, N.; Mandel, I.; Mandic, V.; Mantovani, M.; Marandi, A.; Marchesoni, F.; Marion, F.; Márka, S.; Márka, Z.; Markosyan, A.; Maros, E.; Marque, J.; Martelli, F.; Martin, I. W.; Martin, R. M.; Marx, J. N.; Mason, K.; Masserot, A.; Matichard, F.; Matone, L.; Matzner, R. A.; Mavalvala, N.; Mazzolo, G.; McCarthy, R.; McClelland, D. E.; McDaniel, P.; McGuire, S. C.; McIntyre, G.; McIver, J.; McKechan, D. J. A.; Meadors, G. D.; Mehmet, M.; Meier, T.; Melatos, A.; Melissinos, A. C.; Mendell, G.; Menendez, D.; Mercer, R. A.; Meshkov, S.; Messenger, C.; Meyer, M. S.; Miao, H.; Michel, C.; Milano, L.; Miller, J.; Minenkov, Y.; Mitrofanov, V. P.; Mitselmakher, G.; Mittleman, R.; Miyakawa, O.; Moe, B.; Moesta, P.; Mohan, M.; Mohanty, S. D.; Mohapatra, S. R. P.; Moraru, D.; Moreno, G.; Morgado, N.; Morgia, A.; Mori, T.; Mosca, S.; Mossavi, K.; Mours, B.; Mow-Lowry, C. M.; Mueller, C. L.; Mueller, G.; Mukherjee, S.; Mullavey, A.; Müller-Ebhardt, H.; Munch, J.; Murphy, D.; Murray, P. G.; Mytidis, A.; Nash, T.; Naticchioni, L.; Nawrodt, R.; Necula, V.; Nelson, J.; Newton, G.; Nishizawa, A.; Nocera, F.; Nolting, D.; Nuttall, L.; Ochsner, E.; O'Dell, J.; Oelker, E.; Ogin, G. H.; Oh, J. J.; Oh, S. H.; Oldenburg, R. G.; O'Reilly, B.; O'Shaughnessy, R.; Osthelder, C.; Ott, C. D.; Ottaway, D. J.; Ottens, R. S.; Overmier, H.; Owen, B. J.; Page, A.; Pagliaroli, G.; Palladino, L.; Palomba, C.; Pan, Y.; Pankow, C.; Paoletti, F.; Papa, M. A.; Parisi, M.; Pasqualetti, A.; Passaquieti, R.; Passuello, D.; Patel, P.; Pedraza, M.; Peiris, P.; Pekowsky, L.; Penn, S.; Peralta, C.; Perreca, A.; Persichetti, G.; Phelps, M.; Pickenpack, M.; Piergiovanni, F.; Pietka, M.; Pinard, L.; Pinto, I. M.; Pitkin, M.; Pletsch, H. J.; Plissi, M. V.; Poggiani, R.; Pöld, J.; Postiglione, F.; Prato, M.; Predoi, V.; Price, L. R.; Prijatelj, M.; Principe, M.; Privitera, S.; Prix, R.; Prodi, G. A.; Prokhorov, L.; Puncken, O.; Punturo, M.; Puppo, P.; Quetschke, V.; Raab, F. J.; Rabeling, D. S.; Rácz, I.; Radkins, H.; Raffai, P.; Rakhmanov, M.; Ramet, C. R.; Rankins, B.; Rapagnani, P.; Rapoport, S.; Raymond, V.; Re, V.; Redwine, K.; Reed, C. M.; Reed, T.; Regimbau, T.; Reid, S.; Reitze, D. H.; Ricci, F.; Riesen, R.; Riles, K.; Robertson, N. A.; Robinet, F.; Robinson, C.; Robinson, E. L.; Rocchi, A.; Roddy, S.; Rodriguez, C.; Rodruck, M.; Rolland, L.; Rollins, J.; Romano, J. D.; Romano, R.; Romie, J. H.; Rosińska, D.; Röver, C.; Rowan, S.; Rüdiger, A.; Ruggi, P.; Ryan, K.; Ryll, H.; Sainathan, P.; Sakosky, M.; Salemi, F.; Samblowski, A.; Sammut, L.; Sancho de La Jordana, L.; Sandberg, V.; Sankar, S.; Sannibale, V.; Santamaría, L.; Santiago-Prieto, I.; Santostasi, G.; Sassolas, B.; Sathyaprakash, B. S.; Sato, S.; Saulson, P. R.; Savage, R. L.; Schilling, R.; Schlamminger, S.; Schnabel, R.; Schofield, R. M. S.; Schulz, B.; Schutz, B. F.; Schwinberg, P.; Scott, J.; Scott, S. M.; Searle, A. C.; Seifert, F.; Sellers, D.; Sengupta, A. S.; Sentenac, D.; Sergeev, A.; Shaddock, D. A.; Shaltev, M.; Shapiro, B.; Shawhan, P.; Shoemaker, D. H.; Sibley, A.; Siemens, X.; Sigg, D.; Singer, A.; Singer, L.; Sintes, A. M.; Skelton, G.; Slagmolen, B. J. J.; Slutsky, J.; Smith, J. R.; Smith, M. R.; Smith, N. D.; Smith, R. J. E.; Somiya, K.; Sorazu, B.; Soto, J.; Speirits, F. C.; Sperandio, L.; Stefszky, M.; Stein, A. J.; Steinert, E.; Steinlechner, J.; Steinlechner, S.; Steplewski, S.; Stochino, A.; Stone, R.; Strain, K. A.; Strigin, S.; Stroeer, A. S.; Sturani, R.; Stuver, A. L.; Summerscales, T. Z.; Sung, M.; Susmithan, S.; Sutton, P. J.; Swinkels, B.; Tacca, M.; Taffarello, L.; Talukder, D.; Tanner, D. B.; Tarabrin, S. P.; Taylor, J. R.; Taylor, R.; Thomas, P.; Thorne, K. A.; Thorne, K. S.; Thrane, E.; Thüring, A.; Titsler, C.; Tokmakov, K. V.; Toncelli, A.; Tonelli, M.; Torre, O.; Torres, C.; Torrie, C. I.; Tournefier, E.; Travasso, F.; Traylor, G.; Trias, M.; Tseng, K.; Ugolini, D.; Urbanek, K.; Vahlbruch, H.; Vajente, G.; Vallisneri, M.; van den Brand, J. F. J.; van den Broeck, C.; van der Putten, S.; van Veggel, A. A.; Vass, S.; Vasuth, M.; Vaulin, R.; Vavoulidis, M.; Vecchio, A.; Vedovato, G.; Veitch, J.; Veitch, P. J.; Veltkamp, C.; Verkindt, D.; Vetrano, F.; Viceré, A.; Villar, A. E.; Vinet, J.-Y.; Vitale, S.; Vitale, S.; Vocca, H.; Vorvick, C.; Vyatchanin, S. P.; Wade, A.; Waldman, S. J.; Wallace, L.; Wan, Y.; Wang, X.; Wang, Z.; Wanner, A.; Ward, R. L.; Was, M.; Wei, P.; Weinert, M.; Weinstein, A. J.; Weiss, R.; Wen, L.; Wen, S.; Wessels, P.; West, M.; Westphal, T.; Wette, K.; Whelan, J. T.; Whitcomb, S. E.; White, D.; Whiting, B. F.; Wilkinson, C.; Willems, P. A.; Williams, H. R.; Williams, L.; Willke, B.; Winkelmann, L.; Winkler, W.; Wipf, C. C.; Wiseman, A. G.; Wittel, H.; Woan, G.; Wooley, R.; Worden, J.; Yablon, J.; Yakushin, I.; Yamamoto, H.; Yamamoto, K.; Yang, H.; Yeaton-Massey, D.; Yoshida, S.; Yu, P.; Yvert, M.; Zadroźny, A.; Zanolin, M.; Zendri, J.-P.; Zhang, F.; Zhang, L.; Zhang, W.; Zhang, Z.; Zhao, C.; Zotov, N.; Zucker, M. E.; Zweizig, J.; Akerlof, C.; Boer, M.; Fender, R.; Gehrels, N.; Klotz, A.; Ofek, E. O.; Smith, M.; Sokolowski, M.; Stappers, B. W.; Steele, I.; Swinbank, J.; Wijeres, R. A. M. J.

    2012-04-01

    Aims: A transient astrophysical event observed in both gravitational wave (GW) and electromagnetic (EM) channels would yield rich scientific rewards. A first program initiating EM follow-ups to possible transient GW events has been developed and exercised by the LIGO and Virgo community in association with several partners. In this paper, we describe and evaluate the methods used to promptly identify and localize GW event candidates and to request images of targeted sky locations. Methods: During two observing periods (Dec. 17, 2009 to Jan. 8, 2010 and Sep. 2 to Oct. 20, 2010), a low-latency analysis pipeline was used to identify GW event candidates and to reconstruct maps of possible sky locations. A catalog of nearby galaxies and Milky Way globular clusters was used to select the most promising sky positions to be imaged, and this directional information was delivered to EM observatories with time lags of about thirty minutes. A Monte Carlo simulation has been used to evaluate the low-latency GW pipeline's ability to reconstruct source positions correctly. Results: For signals near the detection threshold, our low-latency algorithms often localized simulated GW burst signals to tens of square degrees, while neutron star/neutron star inspirals and neutron star/black hole inspirals were localized to a few hundred square degrees. Localization precision improves for moderately stronger signals. The correct sky location of signals well above threshold and originating from nearby galaxies may be observed with ~50% or better probability with a few pointings of wide-field telescopes.

  14. Implementation and Testing of the First Prompt for Electromagnetic Counterparts to Gravitational Wave Transients

    NASA Technical Reports Server (NTRS)

    Abadie, J.; Abbott, B. P.; Abbott, R.; Abbott, T. D.; Abernathy, M.; Accadia, T.; Acernese, F.; Adams, C.; Adhikari, R.; Affeldt, C.; Ajith, P.; Allen, B.; Allen, G. S.; Amador Ceron, E.; Amariutei, D.; Amin, R. S.; Anderson, S. B.; Anderson, W. G.; Arai, K.; Arain, M. A.; Araya, M. C.; Blackburn, L.; Camp, J. B.; Cannizzo, J.; Gehrels, N.

    2011-01-01

    A transient astrophysical event observed in both gravitational wave (GW) and electromagnetic (EM) channels would yield rich scientific rewards. A first program initiating EM follow-ups to possible transient GW events has been developed and exercised by the LIGO and Virgo community in association with several partners. In this paper, we describe and evaluate the methods used to promptly identify and localize GW event candidates and to request images of targeted sky locations. Methods. During two observing periods (Dec 17 2009 to Jan 8 2010 and Sep 2 to Oct 20 2010), a low-latency analysis pipeline was used to identify GW-event candidates and to reconstruct-maps of possible sky locations. A catalog of nearby galaxies and Milky Way globular clusters was used to select the most promising sky positions to be imaged, and this directional information was delivered to EM observatories with time lags of about thirty minutes. A Monte Carlo simulation has been used to evaluate the low-latency GW pipeline s ability to reconstruct source positions correctly. Results. For signals near the detection threshold, our low-latency algorithms often localized simulated GW burst signals to tens of square degrees, while neutron star/neutron star inspirals and neutron star/black hole inspirals were localized to a few hundred square degrees. Localization precision improves for moderately stronger signals. The correct sky location of signals well above threshold and originating from nearby galaxies may be observed with 50% or better probability with a few pointings of wide-field telescopes.

  15. Detecting aseismic transients using seismicity

    NASA Astrophysics Data System (ADS)

    Reverso, T.; Marsan, D.; Helmstetter, A.

    2013-12-01

    Aseismic deformation transients occur in different tectonic context. In subduction zones, aseismic slip events are of paramount importance for understanding earthquake hazard, and for estimating the potential for future mega-thrust events. Aseismic slip is however difficult to detect except for the largest cases using GPS data. Here, we propose a systematic detection of aseismic deformation transients based on seismicity data alone. We search for transient increases in background seismicity rate, that would indicate the presence of an aseismic event. To that purpose, we make use of an ETAS model in space and time, to distinguish earthquakes due to background processes from aftershocks. We optimize the model parameters, and test the sensitivity of the results with changes in parameters. Given the 'best' model, we measure the statistical significance of the departure of the local (in time and space) background rate with the 'normal' background rate. Significant departure then indicates the need to temporary increase the background rate in order to explain the observed earthquake occurrences. We thus can single out such episodes of aseismic transients, and characterize their duration and spatial extent. Applying this method to the Aleutian subduction zone reveals several instances of aseismic deformation transients, at various spatial and temporal scales. We further investigate how these transients are organized along the subduction interface, and in time.

  16. Single Stage Contactor Testing Of The Next Generation Solvent Blend

    SciTech Connect

    Herman, D. T.; Peters, T. B.; Duignan, M. R.; Williams, M. R.; Poirier, M. R.; Brass, E. A.; Garrison, A. G.; Ketusky, E. T.

    2014-01-06

    The Modular Caustic Side Solvent Extraction (CSSX) Unit (MCU) facility at the Savannah River Site (SRS) is actively pursuing the transition from the current BOBCalixC6 based solvent to the Next Generation Solvent (NGS)-MCU solvent to increase the cesium decontamination factor. To support this integration of NGS into the MCU facility the Savannah River National Laboratory (SRNL) performed testing of a blend of the NGS (MaxCalix based solvent) with the current solvent (BOBCalixC6 based solvent) for the removal of cesium (Cs) from the liquid salt waste stream. This testing utilized a blend of BOBCalixC6 based solvent and the NGS with the new extractant, MaxCalix, as well as a new suppressor, tris(3,7dimethyloctyl) guanidine. Single stage tests were conducted using the full size V-05 and V-10 liquid-to-liquid centrifugal contactors installed at SRNL. These tests were designed to determine the mass transfer and hydraulic characteristics with the NGS solvent blended with the projected heel of the BOBCalixC6 based solvent that will exist in MCU at time of transition. The test program evaluated the amount of organic carryover and the droplet size of the organic carryover phases using several analytical methods. The results indicate that hydraulically, the NGS solvent performed hydraulically similar to the current solvent which was expected. For the organic carryover 93% of the solvent is predicted to be recovered from the stripping operation and 96% from the extraction operation. As for the mass transfer, the NGS solvent significantly improved the cesium DF by at least an order of magnitude when extrapolating the One-stage results to actual Seven-stage extraction operation with a stage efficiency of 95%.

  17. Single Component Sorption-Desorption Test Experimental Design Approach Discussions

    SciTech Connect

    Phil WInston

    2011-09-01

    A task was identified within the fission-product-transport work package to develop a path forward for doing testing to determine behavior of volatile fission products behavior and to engage members of the NGNP community to advise and dissent on the approach. The following document is a summary of the discussions and the specific approaches suggested for components of the testing. Included in the summary isare the minutes of the conference call that was held with INL and external interested parties to elicit comments on the approaches brought forward by the INL participants. The conclusion was that an initial non-radioactive, single component test will be useful to establish the limits of currently available chemical detection methods, and to evaluated source-dispersion uniformity. In parallel, development of a real-time low-concentration monitoring method is believed to be useful in detecting rapid dispersion as well as desorption phenomena. Ultimately, the test cycle is expected to progress to the use of radio-traced species, simply because this method will allow the lowest possible detection limits. The consensus of the conference call was that there is no need for an in-core test because the duct and heat exchanger surfaces that will be the sorption target will be outside the main neutron flux and will not be affected by irradiation. Participants in the discussion and contributors to the INL approach were Jeffrey Berg, Pattrick Calderoni, Gary Groenewold, Paul Humrickhouse, Brad Merrill, and Phil Winston. Participants from outside the INL included David Hanson of General Atomics, Todd Allen, Tyler Gerczak, and Izabela Szlufarska of the University of Wisconsin, Gary Was, of the University of Michigan, Sudarshan Loyalka and Tushar Ghosh of the University of Missouri, and Robert Morris of Oak Ridge National Laboratory.

  18. Test of Single-Stage Axial-Flow Fan

    NASA Technical Reports Server (NTRS)

    Bell, E Barton

    1942-01-01

    A single-stage axial fan was built and tested in the shop of the propeller-research tunnel of the NACA. The fan comprised a simple 24-blade rotor having a diameter of 21 inches and a solidity of 0.86 and a set of 37 contravanes having a solidity of 1.33. The rotor was driven by a 25-horsepower motor capable of rotating at a speed of 3600 r.p.m. The fan was tested for volume, pressure, and efficiency over a range of delivery pressures and volumes for a wide range of contravane and blade-angle settings. The test results are presented in chart form in terms of nondimensional units in order that similar fans may be accurately designed with a minimum effort. The maximum efficiency (88 percent) was obtained by the fan at a blade angle of 30 degrees and a contravane angle of 70 degrees. An efficiency of 80 percent was obtained by the fan with the contravanes removed.

  19. Thermal Performance Testing of Single Channel GRCop-84 SLM Components

    NASA Technical Reports Server (NTRS)

    Garcia, Chance P.; Cross, Matthew

    2015-01-01

    The surface finish found on components manufactured by sinter laser manufacturing (SLM) is rougher (0.013 - 0.0006 inches) than parts made using traditional fabrication methods. Internal features and passages built into SLM components do not readily allow for roughness reduction processes. Alternatively, engineering literature suggests that the roughness of a surface can enhance thermal performance within a pressure drop regime. To further investigate the thermal performance of SLM fabricated pieces, several GRCop-84 SLM single channel components were tested using a thermal conduction rig at MSFC. A 20 kW power source running at 25% duty cycle and 25% power level applied heat to each component while varying water flow rates between 2.1 - 6.2 gallons/min (GPM) at a supply pressure of 500 to 750 psi. Each test was allowed to reach quasi-steady state conditions where pressure, temperature, and thermal imaging data were recorded. Presented in this work are the heat transfer responses compared to a traditional machined OHFC Copper test section. An analytical thermal model was constructed to anchor theoretical models with the empirical data.

  20. Testing the single degenerate channel for supernova Ia

    NASA Astrophysics Data System (ADS)

    Parsons, Steven

    2014-10-01

    The progenitors of supernova Ia are close binaries containing white dwarfs. Of crucial importance to the evolution of these systems is how much material the white dwarf can stably accrete and hence grow in mass. This occurs during a short-lived intense phase of mass transfer known as the super soft source (SSS) phase. The short duration of this phase and large extinction to soft X-rays means that only a handful are known in our Galaxy. Far more can be learned from the underlying SSS progenitor population of close white dwarf plus FGK type binaries. Unfortunately, these systems are hard to find since the main-sequence stars completely outshine the white dwarfs at optical wavelengths. Because of this, there are currently no known close white dwarf binaries with F, G or early K type companions, making it impossible to determine the contribution of the single degenerate channel towards supernova Ia. Using the GALEX and RAVE surveys we have now identified the first large sample of FGK stars with UV excesses, a fraction of which are these illusive, close systems. Following an intense ground based spectroscopic investigation of these systems, we have identified 5 definite close binaries, with periods of less than a few days. Here we apply for COS spectroscopic observations to measure the mass and temperature of the white dwarfs in order to determine the future evolution of these systems. This will provide a crucial test for the single degenerate channel towards supernova Ia.

  1. Role of Transient Mobility on Submonolayer Island Growth: Extensions and Testing

    NASA Astrophysics Data System (ADS)

    Morales Cifuentes, Josue; Einstein, Theodore; Pimpinelli, Alberto

    In studies of epitaxial growth a major goal is assessing the smallest stable cluster (i + 1 monomers, with i the critical nucleus size), by analyzing the capture zone distribution (CZD) or the scaling of incident flux F to the density of stable islands N (N ~Fα , with α the growth exponent). As noted in the previous talk, the GWD has well described the data in several experiments, including submonolayer para-hexaphenyl (6P) on amorphous mica (i ~ 3). Different scaling (Fα) for 6P at (small) large F is attributed to (DLA) ALA dynamics, i.e. i = (5) 7 +/- 2. Our recent theoretical work considered monomers propagating ballistically before thermalizing or attaching to islands, leading to scaling, non-monotonic crossover, and activation energies that account for the data and reconciling the values of i. We present applications to other experimental systems: 6P on SiO2 and pentacene (5A) on amorphous mica. We describe useful simplifying approximations, and preliminary kinetic Monte Carlo simulations including transient effects on growth. Work at UMD supported by NSF CHE 13-05892.

  2. Dynamic acousto-elastic test using continuous probe wave and transient vibration to investigate material nonlinearity.

    PubMed

    Eiras, J N; Vu, Q A; Lott, M; Payá, J; Garnier, V; Payan, C

    2016-07-01

    This study demonstrates the feasibility of the dynamic acousto-elastic effect of a continuous high frequency wave for investigating the material nonlinearity upon transient vibration. The approach is demonstrated on a concrete sample measuring 15×15×60cm(3). Two ultrasonic transducers (emitter and receiver) are placed at its middle span. A continuous high frequency wave of 500kHz propagates through the material and is modulated with a hammer blow. The position of the hammer blow on the sample is configured to promote the first bending mode of vibration. The use of a continuous wave allows discrete time extraction of the nonlinear behavior by a short-time Fourier transform approach, through the simultaneous comparison of a reference non-modulated signal and an impact-modulated signal. The hammer blow results in phase shifts and variations of signal amplitude between reference and perturbed signals, which are driven by the resonant frequency of the sample. Finally, a comprehensive analysis of the relaxation mechanisms (modulus and attenuation recovery) is conducted to untangle the coupled fast and slow hysteretic effects. PMID:27018754

  3. Estimating transmissivity from single-well pumping tests in heterogeneous aquifers

    NASA Astrophysics Data System (ADS)

    Pechstein, Armin; Attinger, Sabine; Krieg, Ronald; Copty, Nadim K.

    2016-01-01

    Although aquifers are naturally heterogeneous, the interpretation of pumping tests is commonly performed under the assumption of aquifer homogeneity. This yields interpreted hydraulic parameters averaged over a domain of uncertain extent which disguises their relation to the underlying heterogeneity. In this study, we numerically investigate the sensitivity of the transient drawdown at the pumping well, to nonuniform distributions of transmissivity in confined aquifers. Frechet kernels and their time derivative are used to estimate two spatially averaged transmissivities, denoted the equivalent and interpreted transmissivity, Teq and Tin, respectively, for the case of single-well pumping tests. Interrelating Teq and Tin is achieved by modeling Tin in terms of a distance dependent, radially heterogeneous field. In weakly heterogeneous aquifers, Teq approximates TPW, the local transmissivity at the pumped well. With increasing degree of heterogeneity, Teq deviates from TPW as pumping propagates. Tin starts at TPW, approaching the spatial geometric mean of transmissivity during late pumping times. Limits of the proposed spatial weighting functions are investigated by treating the interpreted storativity, Sest, as an indicator for flow connectivity. It is shown numerically that the spatial weights for Teq and Tin agree well to the underlying heterogeneity if . Finally, implications for applying the concepts of Teq and Tin to heterogeneous domains, and, for real world applications are discussed. It is found that time-dependent spatial averages of Tin agree well with estimates of the interpreted transmissivity from the Continuous-Derivation method.

  4. Radiation tests for a single-GEM-loaded gaseous detector

    NASA Astrophysics Data System (ADS)

    Lee, Kyong Sei; Hong, Byungsik; Park, Sung Keun; Kim, Sang Yeol

    2014-11-01

    We report on a systematic study of a single-gas-electron-multiplier (GEM)-loaded gaseous detector developed for precision measurements of high-energy particle beams and for dose verification in particle therapy. In the present study, a 256-channel prototype detector having an active area of 16 × 16 cm2 and operating using a continuous current-integration-mode signal-processing method was manufactured and tested with X-rays emitted from a 70-kV X-ray generator and 43-MeV protons provided by the MC50 proton cyclotron at the Korea Institute of Radiological and Medical Science (KIRAMS). The amplified detector response was measured for X-rays with an intensity of about 5 × 106 Hz cm-2. The linearity of the detector response to the particle flux was examined and validated by using 43-MeV proton beams. The non-uniform development of the amplification for the gas electrons in space was corrected by applying a proper calibration to the channel responses of the measured beam-profile data. We conclude from the radiation tests that the detector developed in the present study will allow us to perform quality measurements of various high-energy particle beams and to apply the technology to dose-verification measurements in particle therapy.

  5. Results of the latest transient well pressure tests at Cerro Prieto

    SciTech Connect

    Abril G, A.; Vargas G, C.

    1981-01-01

    The equipment used in the interference and two-rate flow tests carried out at the Cerro Prieto geothermal field during 1980 are described. The results of two interference tests are presented, one between wells M-110 and M-104, and the other between wells M-7 and Q-757. The data was interpreted using type curve matching analysis. Results of two-rate flow tests carried out in wells M-102 and M-7 are also discussed. A technique for making two-rate flow tests is proposed. This approach, which attempts to avoid the uncertainty of present flow-rate measurements, makes use of devices for direct measurements of separated water and steam. Conclusions based on the above interpretations and recommendations for future tests are presented.

  6. Geological Hypothesis Testing and Investigations of Coupling with Transient Electromagnetics (TEM)

    NASA Astrophysics Data System (ADS)

    Adams, A. C.; Moeller, M. M.; Snyder, E.; Workman, E. J.; Urquhart, S.; Bedrosian, P.; Pellerin, L.

    2014-12-01

    Transient electromagnetic (TEM) data were acquired in Borrego Canyon within the Santo Domingo Basin of the Rio Grande Rift, central New Mexico, during the 2014 Summer of Applied Geophysical Experience (SAGE) field program. TEM surveys were carried out in several regions both to investigate geologic structure and to illustrate the effects of coupling to anthropogenic structures. To determine an optimal survey configuration, 50, 100 and 200 m square transmitter loops were deployed; estimates of depth-of-investigation and logistical considerations determined that 50 m loops were sufficient for production-style measurements. A resistive (100s of ohm-m) layer was identified at a depth of 25-75 m at several locations, and interpreted as dismembered parts of one or more concealed volcanic flows, an interpretation consistent with Tertiary volcanic flows that cap the Santa Anna Mesa immediately to the south. TEM soundings were also made across an inferred fault to investigate whether fault offset is accompanied by lateral changes in electrical resistivity. Soundings within several hundred meters of the inferred fault strand were identical, indicating no resistivity contrast across the fault, and possibly an absence of recent activity. An old windmill and water tank, long-abandoned, offered an excellent laboratory to study the effect of coupling to metallic anthropogenic structures. The character of the measured data strongly suggests the water tank is in electrical contact with the earth (galvanic coupling), and an induced response was persistent to more than 1 second after current turn-off. Coupling effects could be identified at least 150 meters from the tank. Understanding the mechanism behind such coupling and the ability to identify coupled data are critical skills, as one-dimensional modeling of data is affected by such coupling producing artificial conductive layers at depth.

  7. The Mirrortron experiment: A proof of principle test for a method of generating high transient potentials

    SciTech Connect

    Douglass, S.R.

    1993-09-01

    The Mirrortron is a concept in which heavy ions are accelerated by a large local transient space potential that is produced in a hot electron plasma. The purpose of this experiment is to begin a proof of principle experiment to investigate the feasibility of producing this space potential and its associated electric field. If a large magnetic field is suddenly generated in a hot electron plasma with a loss-cone distribution, then potentials on the order of the electron temperature are expected. This potential lasts a few tens of nanoseconds. The investigation begins with a theoretical analysis of this phenomenon giving the space potential as a function of the applied magnetic field. The theory is further extended to cases of relativistic electron distributions. This is then followed by design work on a mirror confinement system for hot electrons. In this experiment a 50--100 keV electron temperature plasma is created with electron cyclotron resonance heating using two frequencies of relatively low microwave power. The microwaves are coupled to resonant frequencies of the vacuum chamber. The volume averaged plasma density is measured to be in the 10{sup 9} cm{sup {minus}3} range. A strap coil and a flat Blumlein transmission line pulse generator were developed to produce a 150 gauss field within 70 ns. The strap coil was placed at the midplane of the mirror field, where the field is 700 gauss. Based on theoretical estimates and computer simulations a 20 kV potential is expected. Measurement of this potential is derived from the modulation of the current of a monoenergetic electron beam after it passes through the high potential region. The variation in the beam energy allows bunching to occur in transit to the detector.

  8. A Randomized, Double-Blind, Single-Dose, Placebo-Controlled, Multicenter, Polysomnographic Study of Gabapentin in Transient Insomnia Induced by Sleep Phase Advance

    PubMed Central

    Rosenberg, Russell P.; Hull, Steven G.; Lankford, D. Alan; Mayleben, David W.; Seiden, David J.; Furey, Sandy A.; Jayawardena, Shyamalie; Roth, Thomas

    2014-01-01

    Study Objectives: To evaluate the effects of single doses of gabapentin 250 and 500 mg on polysomnographic (PSG) and participant-reported sleep measures in a 5-h phase advance insomnia model. Methods: Adults reporting occasional disturbed sleep received gabapentin 500 mg (n = 125), 250 mg (n = 125), or placebo (n = 127) 30 min prior to bedtime and were in bed from 17:00 to 01:00, ∼5 h before their habitual bedtime. Sleep was assessed by PSG, post-sleep questionnaire, and the Karolinska Sleep Diary (KSD). Next-day residual effects (Digit Symbol Substitution Test [DSST] and Stanford Sleepiness Scale [SSS]) and tolerability were assessed. Results: Demographics were comparable among groups. Among PSG endpoints, wake after sleep onset (primary endpoint) (135.7 [placebo], 100.7 [250 mg], and 73.2 [500 mg] min) was significantly lower and total sleep time (TST) (311.4, 356.5, and 378.7 min) significantly greater in both gabapentin groups versus placebo. Latency to persistent sleep was not significantly different among groups. Percent slow wave sleep (12.6%, 15.4%, and 17.0%, respectively) was significantly greater and percent stage 1 (15.1%, 11.8%, and 10.8%, respectively) significantly lower relative to placebo. Gabapentin was associated with significantly higher values of KSD Sleep Quality Index and reported TST versus placebo; no other reported outcomes were significant. Neither gabapentin dose produced evidence of next-day residual effects as measured by DSST and SSS. Adverse events were infrequent (< 5%). Conclusion: Participants with occasional disturbed sleep treated with gabapentin showed significantly longer sleep duration and greater depth (versus placebo) in response to a phase advance manipulation known to disrupt sleep maintenance. Citation: Rosenberg RP, Hull SG, Lankford DA, Mayleben DW, Seiden DJ, Furey SA, Jayawardena S, Roth T. A randomized, double-blind, single-dose, placebo-controlled, multicenter, polysomnographic study of gabapentin in transient insomnia induced by sleep phase advance. J Clin Sleep Med 2014;10(10):1093-1100. PMID:25317090

  9. The collection and analysis of transient test data using the mobile instrumentation data acquisition system (MIDAS)

    SciTech Connect

    Uncapher, W.L.; Arviso, M.

    1995-12-31

    Packages designed to transport radioactive materials are required to survive exposure to environments defined in Code of Federal Regulations. Cask designers can investigate package designs through structural and thermal testing of full-scale packages, components, or representative models. The acquisition of reliable response data from instrumentation measurement devices is an essential part of this testing activity. Sandia National Laboratories, under the sponsorship of the US Department of Energy (DOE), has developed the Mobile Instrumentation Data Acquisition System (MIDAS) dedicated to the collection and processing of structural and thermal data from regulatory tests.

  10. Numerical study of the SSME nozzle flow fields during transient operations: A comparison of the animated results with test

    NASA Technical Reports Server (NTRS)

    Wang, Ten-See; Dumas, Catherine

    1993-01-01

    A computational fluid dynamics (CFD) model has been applied to study the transient flow phenomena of the nozzle and exhaust plume of the Space Shuttle Main Engine (SSME), fired at sea level. The CFD model is a time accurate, pressure based, reactive flow solver. A six-species hydrogen/oxygen equilibrium chemistry is used to describe the chemical-thermodynamics. An adaptive upwinding scheme is employed for the spatial discretization, and a predictor, multiple corrector method is used for the temporal solution. Both engine start-up and shut-down processes were simulated. The elapse time is approximately five seconds for both cases. The computed results were animated and compared with the test. The images for the animation were created with PLOT3D and FAST and then animated with ABEKAS. The hysteresis effects, and the issues of free-shock separation, restricted-shock separation and the end-effects were addressed.

  11. Destruction of a single chlorophyll is correlated with the photoinhibition of photosystem II with a transiently inactive donor side.

    PubMed Central

    Bumann, D; Oesterhelt, D

    1995-01-01

    Pigments destroyed during photoinhibition of water-splitting photosystem II core complexes from the green alga Chlamydomonas reinhardtii were studied. Under conditions of a transiently inactivated donor side, illumination leads to an irreversible inhibition of the electron transfer at the donor side that is paralleled by the destruction of chlorophylls a absorbing maximally around 674 and 682 nm. The observed stochiometry of 1 +/- 0.1 destroyed chlorophyll per inhibited photosystem II suggests that chlorophyll destruction could be the primary photodamage causing the inhibition of photosystem II under these conditions. PMID:11607621

  12. Photo-Induced Current Transient Spectroscopy of Semi-insulating Single Crystal Cs2Hg6S7

    NASA Astrophysics Data System (ADS)

    Liu, Z.; Peters, J. A.; Li, H.; Kanatzidis, M. G.; Im, J.; Jin, H.; Freeman, A. J.; Wessels, B. W.

    2014-09-01

    The ternary compound Cs2Hg6S7 has shown considerable promise as a wide gap semiconductor for hard radiation detection at room temperature. We report on the measurement of defect levels in Cs2Hg6S7 using photo-induced current transient spectroscopy. We observe a series of defect levels with mean activation energies of 0.053, 0.052, 0.34, 0.35, and 0.46 eV. The defects are attributed to Cs vacancies and Cs and Hg antisite defects. Defect capture cross-sections are in the range 10-20-10-15 cm2.

  13. Photo-Induced Current Transient Spectroscopy of Semi-insulating Single Crystal Cs2Hg6S7

    NASA Astrophysics Data System (ADS)

    Liu, Z.; Peters, J. A.; Li, H.; Kanatzidis, M. G.; Im, J.; Jin, H.; Freeman, A. J.; Wessels, B. W.

    2015-01-01

    The ternary compound Cs2Hg6S7 has shown considerable promise as a wide gap semiconductor for hard radiation detection at room temperature. We report on the measurement of defect levels in Cs2Hg6S7 using photo-induced current transient spectroscopy. We observe a series of defect levels with mean activation energies of 0.053, 0.052, 0.34, 0.35, and 0.46 eV. The defects are attributed to Cs vacancies and Cs and Hg antisite defects. Defect capture cross-sections are in the range 10-20-10-15 cm2.

  14. 40 CFR 1048.510 - What transient duty cycles apply for laboratory testing?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... cycle statistics and compare with the established criteria as specified in 40 CFR 1065.514 to confirm... emissions during the next test will accurately represent those from an engine starting at room temperature. For example, if an engine starting at room temperature warms up enough in three minutes to...

  15. 40 CFR 1048.510 - What transient duty cycles apply for laboratory testing?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... cycle statistics and compare with the established criteria as specified in 40 CFR 1065.514 to confirm... emissions during the next test will accurately represent those from an engine starting at room temperature. For example, if an engine starting at room temperature warms up enough in three minutes to...

  16. 40 CFR 1048.510 - What transient duty cycles apply for laboratory testing?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... cycle statistics and compare with the established criteria as specified in 40 CFR 1065.514 to confirm... emissions during the next test will accurately represent those from an engine starting at room temperature. For example, if an engine starting at room temperature warms up enough in three minutes to...

  17. Phase V of the single-breath washout test

    NASA Technical Reports Server (NTRS)

    Nichol, G. M.; Michels, D. B.; Guy, H. J. B.

    1982-01-01

    A downward-deflecting phase V is often seen following the terminal rise (phase IV) in single-breath washout tests. To investigate the nature of phase V, experiments using simultaneous washouts of N2 and tracer boluses of Ar were performed on eight normal nonsmoking subjects aged 27-41 who exhibited a phase V. Phase V is found to occur in all subjects at expiratory flow rates between 0.1 and 2.0 l/sec shortly after expiration became flow limited. Volumes of both phases IV and V increase with increasing flow rate. The difference between the exhaled volumes at which flow became limited and phase V appeared is shown to be approximately equal to the anatomic dead space. Results support a model of lung emptying in a gravitational field in which flow limitation occurs first in the lower lung regions and then progresses toward the upper regions, causing phase IV. A decrease in the amount of flow from the upper relative to the lower regions after all regions have become flow limited then causes phase V.

  18. Bodcau In Situ Combustion Project pressure transient testing. Topical report of January 1978

    SciTech Connect

    Bandyopadhyay, P.; Joseph, C.

    1980-02-01

    The objectives of the falloff tests conducted prior to ignition in August and September 1976 and again in February 1977, were to determine the injection wellbore conditions and pattern flow capacities and to determine how or if the burning process affects them. Pulse tests were conducted to determine directional permeabilities within patterns in order to assist in predicting the combustion front movement. The tests were conducted by shutting off injection into the central injector and subsequently monitoring the tubinghead pressure at that injector, as well as the gas production rates at the offset producing wells. Injection was then restarted and the offset wells' gas production monitored until it was near the initial rate. Analysis of the falloff tests indicates that the advance of the firefront results in large increases in the formation flow capacity and average permeability around the injection wells. Pulse tests analysis, on the other hand, is not so simply understood. The dip of the formation is responsible for generally higher gas mobility (low lag times) toward the south. However, notable deviation occurs in certain patterns due to local anomalies in rock character, saturations and even possibly dip. The lag time measurements on each well defines its particular degree of connectedness to the offset injector. These lag times should be directly connected to the time required for breakthrough of the firefront at that well.While local variations in reservoir properties must be considered in looking at the behavior of a particular well, the overall average behavior should be considered when selecting pattern configuration. The generally increased gas flow toward the south, previously mentioned, indicates that elongation of the patterns toward the south was indeed justified even though some premature breakthrough toward the north will occur due to local variations in geology.

  19. Numerical and field tests of hydraulic transients at Piva power plant

    NASA Astrophysics Data System (ADS)

    Giljen, Z.

    2014-03-01

    In 2009, a sophisticated field investigation was undertaken and later, in 2011, numerical tests were completed, on all three turbine units at the Piva hydroelectric power plant. These tests were made in order to assist in making decisions about the necessary scope of the reconstruction and modernisation of the Piva hydroelectric power plant, a plant originally constructed in the mid-1970s. More specifically, the investigation included several hydraulic conditions including both the start-up and stopping of each unit, load rejection under governor control from different initial powers, as well as emergency shut-down. Numerical results were obtained using the method of characteristics in a representation that included the full flow system and the characteristics of each associated Francis turbine. The impact of load rejection and emergency shut-down on the penstock pressure and turbine speed changes are reported and numerical and experimental results are compared, showing close agreement.

  20. Single-cell-derived mesenchymal stem cells overexpressing Csx/Nkx2.5 and GATA4 undergo the stochastic cardiomyogenic fate and behave like transient amplifying cells

    SciTech Connect

    Yamada, Yoji; Sakurada, Kazuhiro; Takeda, Yukiji; Gojo, Satoshi; Umezawa, Akihiro . E-mail: umezawa@1985.jukuin.keio.ac.jp

    2007-02-15

    Bone marrow-derived stromal cells can give rise to cardiomyocytes as well as adipocytes, osteocytes, and chondrocytes in vitro. The existence of mesenchymal stem cells has been proposed, but it remains unclear if a single-cell-derived stem cell stochastically commits toward a cardiac lineage. By single-cell marking, we performed a follow-up study of individual cells during the differentiation of 9-15c mesenchymal stromal cells derived from bone marrow cells. Three types of cells, i.e., cardiac myoblasts, cardiac progenitors and multipotent stem cells were differentiated from a single cell, implying that cardiomyocytes are generated stochastically from a single-cell-derived stem cell. We also demonstrated that overexpression of Csx/Nkx2.5 and GATA4, precardiac mesodermal transcription factors, enhanced cardiomyogenic differentiation of 9-15c cells, and the frequency of cardiomyogenic differentiation was increased by co-culturing with fetal cardiomyocytes. Single-cell-derived mesenchymal stem cells overexpressing Csx/Nkx2.5 and GATA4 behaved like cardiac transient amplifying cells, and still retained their plasticity in vivo.

  1. Numerical Examination of the Effective Investigation Areas by Single-Well Hydraulic Tests in Low-Permeability Environments

    NASA Astrophysics Data System (ADS)

    Takeda, M.; Zhang, M.; Nakajima, H.

    2005-12-01

    In-situ permeability tests are indispensable for hydraulic characterizations of investigate areas for the geological disposal of radioactive nuclear waste. The single-well permeability tests are preferable in the course of site selection, and the derived hydraulic parameters are important indices of the capabilities of a candidate site to retard nuclide migration and the parameters required for the subsequent prediction of nuclide fate based on transport modeling. However, the hydraulic parameters obtained from any in-situ permeability test may only reflect the hydraulic characteristics of the area around the well that has experienced a pressure disturbance due to the test. Since the area influenced during a test depends on the test time, hydraulic characteristics and their distributions in the formation, and the test method itself, the parameters derived from a test data may vary between tests. Accordingly, application of a test result should also consider the effective investigation area of each test method. To examine the effective investigation areas for different types of single-well permeability test in low permeability environments, numerical simulations for the major test methods, i.e., the pressure pulse test, constant head test, constant rate test, were performed in this study. Pressure responses around the test well, the variations of measurement data and hydraulic gradients around the well were also calculated to assess the behavior of each test method. A series of numerical examinations yielded the following findings: (1)In the constant head and constant rate tests, the influenced areas expand and their response values reach the same values of a constant head and constant flow rate at the well as time elapses. On the other hand, the influenced area in the pulse test is very limited and the induced hydraulic head diminishes within that area. (2)The times required for individual tests to establish the quasi-steady state are almost the same. The duration of transient state in each test method depends on the hydraulic properties of formation and tends to increase in low-permeability environments. (3) The hydraulic gradients around the well reach their maximum values early in the pressure pulse and constant head tests and decrease with time. On the other hand, the hydraulic gradient gradually increases from the vicinity of the well screen with time in the constant rate test.

  2. [Acute stent thrombosis and reverse transient left ventricular dilatation after performing a single-photon emission computed tomography myocardial perfusion].

    PubMed

    Miranda, B; Pizzi, M N; Aguadé-Bruix, S; Domingo, E; Candell-Riera, J

    2015-01-01

    A 63-year-old male patient with a history of stent implantation in the left anterior descending three months before. Due to the presentation of vegetative symptoms, he was referred for gated-SPECT myocardial perfusion. During acquisition of the resting images he presented chest pain and ST segment elevation, so that urgent cardiac catheterization was performed, showing stent thrombosis. Rest perfusion imaging showed a defect in anterior and apical perfusion, more severe and extensive than in the stress images, with striking left ventricular dilatation and a fall in the ejection fraction related to the acute ischemia phenomenon. Intense exercise is associated with a transient activation of the coagulation system and hemodynamic changes that might induce thrombosis, especially in recently implanted coronary stents that probably still have not become completely endothelialized. PMID:25129322

  3. Radiation-Induced Transient Effects in Near Infrared Focal Plane Arrays

    NASA Technical Reports Server (NTRS)

    Reed, Robert A.; Pickel, J.; Marshall, P.; Waczynski, A.; McMurray, R.; Gee, G.; Polidan, E.; Johnson, S.; McKeivey, M.; Ennico, K.; Johnson, R.

    2004-01-01

    This viewgraph presentation describes a test simulate the transient effects of cosmic ray impacts on near infrared focal plane arrays. The objectives of the test are to: 1) Characterize proton single events as function of energy and angle of incidence; 2) Measure charge spread (crosstalk) to adjacent pixels; 3) Assess transient recovery time.

  4. Phase 3 integrated water recovery testing at MSFC: Single loop test results and lessons learned

    NASA Technical Reports Server (NTRS)

    Carter, Donald Layne; Bagdigian, Robert M.

    1993-01-01

    A series of tests has been conducted at the NASA Marshall Space Flight Center (MSFC) to evaluate the performance of the Space Station Freedom (SSF) water recovery system. Potable and urine reclamation processors were integrated with waste water generation equipment and sucessfully operated for a total of 144 days. This testing marked the first occasion in which the waste feed sources for the previous potable and hygiene loops were combined into a single loop and processed to potable water quality. Reclaimed potable water from the combined waste waters routinely met the SSF water quality specifications.In the last stage of testing, data was obtained that indicated that the water processor (WP) presterilizer may not be required to meet the potable water quality specification. The removal of the presterilizer from the Water Processor design would provide a significant power savings, though an increase in the residence time of the catalytic oxidation reactor may be required to meet the potable microbial and total Organic Carbon specifications. This paper summarizes the test objectives, system design, test activities/protocols, significant results/anomalies and major lessons learned.

  5. Acoustic Data Processing and Transient Signal Analysis for the Hybrid Wing Body 14- by 22-Foot Subsonic Wind Tunnel Test

    NASA Technical Reports Server (NTRS)

    Bahr, Christopher J.; Brooks, Thomas F.; Humphreys, William M.; Spalt, Taylor B.; Stead, Daniel J.

    2014-01-01

    An advanced vehicle concept, the HWB N2A-EXTE aircraft design, was tested in NASA Langley's 14- by 22-Foot Subsonic Wind Tunnel to study its acoustic characteristics for var- ious propulsion system installation and airframe con gurations. A signi cant upgrade to existing data processing systems was implemented, with a focus on portability and a re- duction in turnaround time. These requirements were met by updating codes originally written for a cluster environment and transferring them to a local workstation while en- abling GPU computing. Post-test, additional processing of the time series was required to remove transient hydrodynamic gusts from some of the microphone time series. A novel automated procedure was developed to analyze and reject contaminated blocks of data, under the assumption that the desired acoustic signal of interest was a band-limited sta- tionary random process, and of lower variance than the hydrodynamic contamination. The procedure is shown to successfully identify and remove contaminated blocks of data and retain the desired acoustic signal. Additional corrections to the data, mainly background subtraction, shear layer refraction calculations, atmospheric attenuation and microphone directivity corrections, were all necessary for initial analysis and noise assessments. These were implemented for the post-processing of spectral data, and are shown to behave as expected.

  6. 49 CFR 232.307 - Modification of the single car air brake test procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Modification of the single car air brake test... Requirements § 232.307 Modification of the single car air brake test procedures. (a) Request. The AAR or other authorized representative of the railroad industry may seek modification of the single car air brake...

  7. 49 CFR 232.307 - Modification of the single car air brake test procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Modification of the single car air brake test... Requirements § 232.307 Modification of the single car air brake test procedures. (a) Request. The AAR or other authorized representative of the railroad industry may seek modification of the single car air brake...

  8. 49 CFR 232.307 - Modification of the single car air brake test procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Modification of the single car air brake test... Requirements § 232.307 Modification of the single car air brake test procedures. (a) Request. The AAR or other authorized representative of the railroad industry may seek modification of the single car air brake...

  9. 49 CFR 232.307 - Modification of the single car air brake test procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Modification of the single car air brake test... Requirements § 232.307 Modification of the single car air brake test procedures. (a) Request. The AAR or other authorized representative of the railroad industry may seek modification of the single car air brake...

  10. Summary of air permeability data from single-hole injection tests in unsaturated fractured tuffs at the Apache Leap Research Site: Results of steady-state test interpretation

    SciTech Connect

    Guzman, A.G.; Geddis, A.M.; Henrich, M.J.; Lohrstorfer, C.F.; Neuman, S.P.

    1996-03-01

    This document summarizes air permeability estimates obtained from single hole pneumatic injection tests in unsaturated fractured tuffs at the Covered Borehole Site (CBS) within the larger apache Leap Research Site (ALRS). Only permeability estimates obtained from a steady state interpretation of relatively stable pressure and flow rate data are included. Tests were conducted in five boreholes inclined at 45{degree} to the horizontal, and one vertical borehole. Over 180 borehole segments were tested by setting the packers 1 m apart. Additional tests were conducted in segments of lengths 0.5, 2.0, and 3.0 m in one borehole, and 2.0 m in another borehole, bringing the total number of tests to over 270. Tests were conducted by maintaining a constant injection rate until air pressure became relatively stable and remained so for some time. The injection rate was then incremented by a constant value and the procedure repeated. The air injection rate, pressure, temperature, and relative humidity were recorded. For each relatively stable period of injection rate and pressure, air permeability was estimated by treating the rock around each test interval as a uniform, isotropic porous medium within which air flows as a single phase under steady state, in a pressure field exhibiting prolate spheroidal symmetry. For each permeability estimate the authors list the corresponding injection rate, pressure, temperature and relative humidity. They also present selected graphs which show how the latter quantities vary with time; logarithmic plots of pressure versus time which demonstrate the importance of borehole storage effects during the early transient portion of each incremental test period; and semilogarithmic plots of pressure versus recovery time at the end of each test sequence.

  11. Single- and double-core-hole ion emission spectroscopy of transient neon plasmas produced by ultraintense x-ray laser pulses

    NASA Astrophysics Data System (ADS)

    Gao, Cheng; Zeng, Jiaolong; Yuan, Jianmin

    2016-02-01

    Single-core-hole (SCH) and double-core-hole (DCH) spectroscopy is investigated systematically for neon gas in the interaction with ultraintense x-ray pulses with photon energy from 937 eV to 2000 eV. A time-dependent rate equation, implemented in detailed level accounting approximation, is utilized to study the dynamical evolution of the level population and emission properties of the laser-produced highly transient plasmas. The plasma-density effects on level populations and charge-state distribution are demonstrated with an x-ray photon energy of 2000 eV. It is shown that atomic number density of relevant experiment is about 1 × 1018 cm-3, which is comparable to a recent experiment. At this density, we systematically investigate the emissivity of the transient neon plasmas. For laser photon energy in the range 937-1360 eV, resonant absorptions (RA) of 1s\\to {np} (n≥slant 2) transitions play important roles in time evolution of the population and DCH emission spectroscopy. The RA effects are illustrated in detail for an x-ray pulse of 944 eV photon energy, which creates the 1s\\to 2p RA from the SCH states (1s2{s}22{p}4, 1s2s2p5, and 1s2p6) of Ne3+. After averaging over the space and time distribution of x-ray pulse, DCH emission spectroscopy is studied at x-ray photon energies of 937, 944, 955, 968, 980, and 990 eV, where there exist 1s\\to 2p resonances from SCH states of Ne2+-Ne7+. The processes with producing DCH states are discussed. For x-ray photon energy larger than 1360 eV, no RA exist and transient plasmas show different features in the DCH spectroscopy.

  12. Mechanical testing of large thallium doped sodium iodide single crystals

    NASA Technical Reports Server (NTRS)

    Lee, H. M.

    1985-01-01

    The findings of mechanical tests performed on five thallium-doped sodium iodide NaI(Tl) crystals are presented. These crystals are all in the shape of circular flat plates, 20.0 in. in diameter an d0.5 in. thick. The test setup, testing procedure, and the test data are presented. Large crystals exhibit a high degree of material plasticity, as well as a much higher strength than previously anticipated, on the order of 500 psi. Also revealed from the testing is the fact that crystal with a large number of grain boundaries developed less plasticity, and therefore less permanent deformation, than those with fewer grain boundaries.

  13. Test report for single event effects of the 80386DX microprocessor

    NASA Technical Reports Server (NTRS)

    Watson, R. Kevin; Schwartz, Harvey R.; Nichols, Donald K.

    1993-01-01

    The Jet Propulsion Laboratory Section 514 Single Event Effects (SEE) Testing and Analysis Group has performed a series of SEE tests of certain strategic registers of Intel's 80386DX CHMOS 4 microprocessor. Following a summary of the test techniques and hardware used to gather the data, we present the SEE heavy ion and proton test results. We also describe the registers tested, along with a system impact analysis should these registers experience a single event upset.

  14. Single-molecule spectroscopy and femtosecond transient absorption studies on the excitation energy transfer process in ApcE(1-240) dimers.

    PubMed

    Long, Saran; Zhou, Meng; Tang, Kun; Zeng, Xiao-Li; Niu, Yingli; Guo, Qianjin; Zhao, Kai-Hong; Xia, Andong

    2015-05-28

    ApcE(1-240) dimers with one intrinsic phycocyanobilin (PCB) chromophore in each monomer that is truncated from the core-membrane linker (ApcE) of phycobilisomes (PBS) in Nostoc sp. PCC 7120 show a sharp and significantly red-shifted absorption. Two explanations either conformation-dependent Förster resonance energy transfer (FRET) or the strong exciton coupling limit have been proposed for red-shifted absorption. This is a classic example of the special pair in the photosynthetic light harvesting proteins, but the mechanism of this interaction is still a matter of intense debate. We report the studies using single-molecule and transient absorption spectra on the interaction in the special pair of ApcE dimers. Our results demonstrate the presence of conformation-dependent FRET between the two PCB chromophores in ApcE dimers. The broad distributions of fluorescence intensities, lifetimes and polarization difference from single-molecule measurements reveal the heterogeneity of local protein-pigment environments in ApcE dimers, where the same molecular structures but different protein environments are the main reason for the two PCB chromophores with different spectral properties. The excitation energy transfer rate between the donor and the acceptor about (110 ps)(-1) is determined from transient absorption measurements. The red-shifted absorption in ApcE dimers could result from more extending conformation, which shows another type of absorption redshift that does not depend on strong exciton coupling. The results here stress the importance of conformation-controlled spectral properties of the chemically identical chromophores, which could be a general feature to control energy/electron transfer, widely existing in the light harvesting complexes. PMID:25925197

  15. Results of the ETV-1 breadboard tests under steady-state and transient conditions. [conducted in the NASA-LeRC Road Load Simulator

    NASA Technical Reports Server (NTRS)

    Sargent, N. B.; Dustin, M. O.

    1981-01-01

    Steady state tests were run to characterize the system and component efficiencies over the complete speed-torque capabilities of the propulsion system in both motoring and regenerative modes of operation. The steady state data were obtained using a battery simulator to separate the effects on efficiency caused by changing battery state-of-charge and component temperature. Transient tests were performed to determine the energy profiles of the propulsion system operating over the SAE J227a driving schedules.

  16. Transient Behaviour of Batch Arrival Queue with N-Policy and Single Vacation (Mx/G/1/N-POLICY)

    NASA Astrophysics Data System (ADS)

    Solanki, Anjana

    2009-07-01

    In this paper Mx/G/1 queuing system with N-policy and single vacation is considered. As soon as the system becomes empty, the server leaves the system for a vacation of random length V. When he returns from the vacation, if the system size is greater then or equal to predetermined value N (threshold), he begins to serve the customers. If not, the server waits in the system until the system size reaches or exceeds N. Here the time dependent system size distribution is obtained.

  17. Thermal modeling of the NASA-Ames Research Center Cryogenic Optical Test Facility and a single-arch, fused-natural-quartz mirror

    NASA Technical Reports Server (NTRS)

    Ng, Y. S.; Augason, Gordon C.; Young, Jeffrey A.; Howard, Steven D.; Melugin, Ramsey K.

    1990-01-01

    A thermal model of the dewar and optical system of the Cryogenic Optical Test Facility at NASA-Ames Research Center was developed using the computer codes SINDA and MONTE CARLO. The model was based on the geometry, boundary conditions, and physical properties of the test facility and was developed to investigate heat transfer mechanisms and temperatures in the facility and in test mirrors during cryogenic optical tests. A single-arch, fused-natural-quartz mirror was the first mirror whose thermal loads and temperature distributions were modeled. From the temperature distribution, the thermal gradients in the mirror were obtained. The model predicted that a small gradient should exist for the single arch mirror. This was later verified by the measurement of mirror temperatures. The temperatures, predicted by the model at various locations within the dewar, were in relatively good agreement with the measured temperatures. The model is applicable to both steady-state and transient cooldown operations.

  18. Qualification test procedures and results for Honeywell solar collector subsystem, single-family residence

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The test procedures and results in qualifying the Honeywell single family residence solar collector subsystem are presented. Testing was done in the following areas: pressure, service loads, hail, solar degradation, pollutants, thermal degradation, and outgassing.

  19. Single photons in an imperfect array of beam-splitters: interplay between percolation, backscattering and transient localization

    NASA Astrophysics Data System (ADS)

    Chandrashekar, C. M.; Melville, S.; Busch, Th

    2014-04-01

    Photons in optical networks can be used in multi-path interferometry and various quantum information processing and communication protocols. Large networks, however, are often not free from defects, which can appear randomly between the lattice sites and are caused either by production faults or deliberate introduction. In this work we present numerical simulations of the behaviour of a single photon injected into a regular lattice of beam-splitting components in the presence of defects that cause perfect backward reflections. We find that the photon dynamics is quickly dominated by the backscattering processes, and a small fraction of reflectors in the paths of the beam-splitting array strongly affects the percolation probability of the photon. We carefully examine such systems and show an interesting interplay between the probabilities of percolation, backscattering and temporary localization. We also discuss the sensitivity of these probabilities to lattice size, timescale, injection point, fraction of reflectors and boundary conditions.

  20. ORNL rod-bundle heat-transfer test data. Volume 3. Thermal-hydraulic test facility experimental data report for test 3. 06. 6B - transient film boiling in upflow. [PWR

    SciTech Connect

    Mullins, C.B.; Felde, D.K.; Sutton, A.G.; Gould, S.S.; Morris, D.G.; Robinson, J.J.

    1982-05-01

    Reduced instrument responses are presented for Thermal-Hyraulic Test Facility (THTF) Test 3.06.6B. This test was conducted by members of the Oak Ridge National Laboratory Pressurized-Water-Reactor (PWR) Blowdown Heat Transfer (BDHT) Separate-Effects Program on August 29, 1980. The objective of the program was to investigate heat transfer phenomena believed to occur in PWR's during accidents, including small and large break loss-of-coolant accidents. Test 3.06.6B was conducted to obtain transient film boiling data in rod bundle geometry under reactor accident-type conditions. The primary purpose of this report is to make the reduced instrument responses for THTF Test 3.06.6B available. Included in the report are uncertainties in the instrument responses, calculated mass flows, and calculated rod powers.

  1. Neutronics, steady-state, and transient analyses for the Poland MARIA reactor for irradiation testing of LEU lead test fuel assemblies from CERCA : ANL independent verification results.

    SciTech Connect

    Garner, P. L.; Hanan, N. A.

    2011-06-07

    The MARIA reactor at the Institute of Atomic Energy (IAE) in Swierk (30 km SE of Warsaw) in the Republic of Poland is considering conversion from high-enriched uranium (HEU) to low-enriched uranium (LEU) fuel assemblies (FA). The FA design in MARIA is rather unique; a suitable LEU FA has never been designed or tested. IAE has contracted with CERCA (the fuel supply portion of AREVA in France) to supply 2 lead test assemblies (LTA). The LTAs will be irradiated in MARIA to burnup level of at least 40% for both LTAs and to 60% for one LTA. IAE may decide to purchase additional LEU FAs for a full core conversion after the test irradiation. The Reactor Safety Committee within IAE and the National Atomic Energy Agency in Poland (PAA) must approve the LTA irradiation process. The approval will be based, in part, on IAE submitting revisions to portions of the Safety Analysis Report (SAR) which are affected by the insertion of the LTAs. (A similar process will be required for the full core conversion to LEU fuel.) The analysis required was established during working meetings between Argonne National Laboratory (ANL) and IAE staff during August 2006, subsequent email correspondence, and subsequent staff visits. The analysis needs to consider the current high-enriched uranium (HEU) core and 4 core configurations containing 1 and 2 LEU LTAs in various core positions. Calculations have been performed at ANL in support of the LTA irradiation. These calculations are summarized in this report and include criticality, burn-up, neutronics parameters, steady-state thermal hydraulics, and postulated transients. These calculations have been performed at the request of the IAE staff, who are performing similar calculations to be used in their SAR amendment submittal to the PAA. The ANL analysis has been performed independently from that being performed by IAE and should only be used as one step in the verification process.

  2. I.v. cocaine induces rapid, transient excitation of striatal neurons via its action on peripheral neural elements: single-cell, iontophoretic study in awake and anesthetized rats.

    PubMed

    Kiyatkin, E A; Brown, P L

    2007-09-21

    Cocaine's (COC) direct interaction with the dopamine (DA) transporter is usually considered the most important action underlying the psychomotor stimulant and reinforcing effects of this drug. However, some physiological, behavioral and psycho-emotional effects of COC are very rapid and brief and they remain intact during DA receptor blockade, suggesting possible involvement of peripheral non-DA neural mechanisms. To assess this issue, single-unit recording with microiontophoresis was used to examine changes in impulse activity of dorsal and ventral striatal neurons to i.v. COC (0.25-0.5 mg/kg) in the same rats under two conditions: awake with DA receptor blockade and anesthetized with urethane. In the awake preparation approximately 70% striatal neurons showed rapid and transient (latency approximately 6 s, duration approximately 15 s) COC-induced excitations. These effects were stronger in ventral than dorsal striatum. During anesthesia, these phasic effects were fully blocked and COC slowly decreased neuronal discharge rate. Cocaine-methiodide (COC-M), a derivative that cannot cross the blood-brain barrier, also caused phasic excitations in the awake, but not anesthetized condition. In contrast to regular COC, COC-M had no tonic effect on discharge rate in either preparation. Most striatal neurons that were phasically excited by both COC forms also showed short-latency excitations during tail-touch and tail-pinch in the awake preparation, an effect strongly attenuated during anesthesia. Finally, most striatal neurons that in awake conditions were phasically excited by somato-sensory stimuli and COC salts were also excited by iontophoretic glutamate (GLU). Although striatal neurons were sensitive to GLU in both preparations, the response magnitude at the same GLU current was higher in awake than anesthetized conditions. These data suggest that in awake animals i.v. COC, like somato-sensory stimuli, transiently excites striatal neurons via its action on peripheral neural elements and rapid neural transmission. While the nature of these neuronal elements needs to be clarified using other analytical techniques, they might involve voltage-gated K(+) and Na(+) channels, which have a high affinity for COC and are located on terminals of visceral sensory nerves that densely innervate peripheral vessels. Therefore, along with direct action on specific brain substrates, central excitatory effects of COC may occur via indirect action, involving afferents of visceral sensory nerves and rapid neural transmission. By providing a rapid sensory signal and triggering transient neural activation, such a peripherally triggered action might play a crucial role in the sensory effects of COC, thus contributing to learning and development of drug-taking behavior. PMID:17706878

  3. Single specimen fracture toughness determination procedure using instrumented impact test

    NASA Astrophysics Data System (ADS)

    Rintamaa, Rauno

    The focus of the work is aimed at two scientific issues. The primary emphasis is directed to development of a method which enables the detection of ductile crack initiation, and hence, the energy-based fracture toughness, by applying an optical crack opening displacement (COD) measuring device. It is claimed that the Double Displacement Ratio (DDR), i.e., the ratio of crack opening displacement vs. specimen displacement, indicates the onset of ductile crack growth initiation in a way which is easy and reliable enough to apply in transition and upper shelf regions of a fracture toughness transition temperature curve. The method is extensively verified by experimental and analytical investigations, and compared with other single specimen methods used for dynamic fracture toughness determination.

  4. Characterization of a Spontaneous Parametric Downconversion Source for Use in Single Photon Tests of Quantum Mechanics

    NASA Astrophysics Data System (ADS)

    Alexander, Preston; McDonld, Jackson; Harrington, Jason; Smith, R. Seth

    2014-03-01

    During the past year, a quantum optics laboratory was constructed and tested at Francis Marion University. A spontaneous parametric downconversion source was used to create pairs of correlated photons for use in single photon tests of quantum mechanics. Photons from a spontaneous parametric downconversion source were detected with single photon counting modules that were purchased through the Advanced Laboratory Physics Association (ALPHA). The effect of pump polarization on the output intensity was studied. Coincidences between pairs of correlated photons were counted and plotted as a function of the angle between the single photon detectors, in order to perform a test of Conservation of Momentum. The laboratory will be used to perform single photon tests of quantum mechanics, including the Grangier experiment, single photon interference, quantum state measurement, and tests of local realism.

  5. Bilateral force transients in the upper limbs evoked by single-pulse microstimulation in the pontomedullary reticular formation

    PubMed Central

    Hirschauer, Thomas J.

    2015-01-01

    Neurons in the pontomedullary reticular formation (PMRF) give rise to the reticulospinal tract. The motor output of the PMRF was investigated using stimulus-triggered averaging of electromyography (EMG) and force recordings in two monkeys (M. fascicularis). EMG was recorded from 12 pairs of upper limb muscles, and forces were detected using two isometric force-sensitive handles. Of 150 stimulation sites, 105 (70.0%) produced significant force responses, and 139 (92.5%) produced significant EMG responses. Based on the average flexor EMG onset latency of 8.3 ms and average force onset latency of 15.9 ms poststimulation, an electromechanical delay of ∼7.6 ms was calculated. The magnitude of force responses (∼10 mN) was correlated with the average change in EMG activity (P < 0.001). A multivariate linear regression analysis was used to estimate the contribution of each muscle to force generation, with flexors and extensors exhibiting antagonistic effects. A predominant force output pattern of ipsilateral flexion and contralateral extension was observed in response to PMRF stimulation, with 65.3% of significant ipsilateral force responses directed medially and posteriorly (P < 0.001) and 78.6% of contralateral responses directed laterally and anteriorly (P < 0.001). This novel approach permits direct measurement of force outputs evoked by central nervous system microstimulation. Despite the small magnitude of poststimulus EMG effects, low-intensity single-pulse microstimulation of the PMRF evoked detectable forces. The forces, showing the combined effect of all muscle activity in the arms, are consistent with reciprocal pattern of force outputs from the PMRF detectable with stimulus-triggered averaging of EMG. PMID:25652926

  6. Predictions of Transient Flame Lift-Off Length With Comparison to Single-Cylinder Optical Engine Experiments

    SciTech Connect

    Senecal, P. K.; Pomraning, E.; Anders, J. W.; Weber, M. R.; Gehrke, C. R.; Polonowski, C. J.; Mueller, C. J.

    2014-05-28

    A state-of-the-art, grid-convergent simulation methodology was applied to three-dimensional calculations of a single-cylinder optical engine. A mesh resolution study on a sector-based version of the engine geometry further verified the RANS-based cell size recommendations previously presented by Senecal et al. (“Grid Convergent Spray Models for Internal Combustion Engine CFD Simulations,” ASME Paper No. ICEF2012-92043). Convergence of cylinder pressure, flame lift-off length, and emissions was achieved for an adaptive mesh refinement cell size of 0.35 mm. Furthermore, full geometry simulations, using mesh settings derived from the grid convergence study, resulted in excellent agreement with measurements of cylinder pressure, heat release rate, and NOx emissions. On the other hand, the full geometry simulations indicated that the flame lift-off length is not converged at 0.35 mm for jets not aligned with the computational mesh. Further simulations suggested that the flame lift-off lengths for both the nonaligned and aligned jets appear to be converged at 0.175 mm. With this increased mesh resolution, both the trends and magnitudes in flame lift-off length were well predicted with the current simulation methodology. Good agreement between the overall predicted flame behavior and the available chemiluminescence measurements was also achieved. Our present study indicates that cell size requirements for accurate prediction of full geometry flame lift-off lengths may be stricter than those for global combustion behavior. This may be important when accurate soot predictions are required.

  7. Predictions of Transient Flame Lift-Off Length With Comparison to Single-Cylinder Optical Engine Experiments

    DOE PAGESBeta

    Senecal, P. K.; Pomraning, E.; Anders, J. W.; Weber, M. R.; Gehrke, C. R.; Polonowski, C. J.; Mueller, C. J.

    2014-05-28

    A state-of-the-art, grid-convergent simulation methodology was applied to three-dimensional calculations of a single-cylinder optical engine. A mesh resolution study on a sector-based version of the engine geometry further verified the RANS-based cell size recommendations previously presented by Senecal et al. (“Grid Convergent Spray Models for Internal Combustion Engine CFD Simulations,” ASME Paper No. ICEF2012-92043). Convergence of cylinder pressure, flame lift-off length, and emissions was achieved for an adaptive mesh refinement cell size of 0.35 mm. Furthermore, full geometry simulations, using mesh settings derived from the grid convergence study, resulted in excellent agreement with measurements of cylinder pressure, heat release rate,more » and NOx emissions. On the other hand, the full geometry simulations indicated that the flame lift-off length is not converged at 0.35 mm for jets not aligned with the computational mesh. Further simulations suggested that the flame lift-off lengths for both the nonaligned and aligned jets appear to be converged at 0.175 mm. With this increased mesh resolution, both the trends and magnitudes in flame lift-off length were well predicted with the current simulation methodology. Good agreement between the overall predicted flame behavior and the available chemiluminescence measurements was also achieved. Our present study indicates that cell size requirements for accurate prediction of full geometry flame lift-off lengths may be stricter than those for global combustion behavior. This may be important when accurate soot predictions are required.« less

  8. Test procedures and instructions for single shell tank saltcake cesium removal with crystalline silicotitanate

    SciTech Connect

    Duncan, J.B.

    1997-01-07

    This document provides specific test procedures and instructions to implement the test plan for the preparation and conduct of a cesium removal test, using Hanford Single Shell Tank Saltcake from tanks 24 t -BY- I 10, 24 1 -U- 108, 24 1 -U- 109, 24 1 -A- I 0 1, and 24 t - S-102, in a bench-scale column. The cesium sorbent to be tested is crystalline siticotitanate. The test plan for which this provides instructions is WHC-SD-RE-TP-024, Hanford Single Shell Tank Saltcake Cesium Removal Test Plan.

  9. COMMIX-1AR/P: A three-dimensional transient single-phase computer program for thermal hydraulic analysis of single and multicomponent systems. Volume 2, User`s guide

    SciTech Connect

    Garner, P.L.; Blomquist, R.N.; Gelbard, E.M.

    1992-09-01

    The COMMIX-1AR/P computer program is designed for analyzing the steady-state and transient aspects of single-phase fluid flow and heat transfer in three spatial dimensions. This version is an extension of the modeling in COMMIX-1A to include multiple fluids in physically separate regions of the computational domain, modeling descriptions for pumps, radiation heat transfer between surfaces of the solids which are embedded in or surround the fluid, a k-{var_epsilon} model for fluid turbulence, and improved numerical techniques. The porous-medium formulation in COMMIX allows the program to be applied to a wide range of problems involving both simple and complex geometrical arrangements. The input preparation and execution procedures are presented for the COMMIX-1AR/P program and several postprocessor programs which produce graphical displays of the calculated results.

  10. Repassivation of 304 stainless steel investigated with a single scratch test

    SciTech Connect

    Adler, T.A.; Walters, R.R. )

    1993-05-01

    Reformation of the passive film on 304 stainless steel (UNSS 30400) was investigated with a scratch test. Regrowth of the passive film was measured by recording the current that resulted from forming the scratch. Charge consumed during the reformation of the film was compared to wear produced by the scratch. The current density from an incremental area of the scratch was extracted from the measured current transients using the width of the scratch as a function of time. The maximum current density and the charge density were dependent linearly on the area fraction of bare surface. Other parameters used in the model of current transients did not change as the area fraction of bare surface changed. Results showed the passive film remained adherent to the surface of the stainless steel during the rubbing mode of wear.

  11. Parametric Testing of Chevrons on Single Flow Hot Jets

    NASA Technical Reports Server (NTRS)

    Bridges, James; Brown, Clifford A.

    2004-01-01

    A parametric family of chevron nozzles have been studied, looking for relationships between chevron geometric parameters, flow characteristics, and far-field noise. Both cold and hot conditions have been run at acoustic Mach number 0.9. Ten models have been tested, varying chevron count, penetration, length, and chevron symmetry. Four comparative studies were defined from these datasets which show: that chevron length is not a major impact on either flow or sound; that chevron penetration increases noise at high frequency and lowers it at low frequency, especially for low chevron counts; that chevron count is a strong player with good low frequency reductions being achieved with high chevron count without strong high frequency penalty; and that chevron asymmetry slightly reduces the impact of the chevron. Finally, it is shown that although the hot jets differ systematically from the cold one, the overall trends with chevron parameters is the same.

  12. Effect of supply voltage and body-biasing on single-event transient pulse quenching in bulk fin field-effect-transistor process

    NASA Astrophysics Data System (ADS)

    Jun-Ting, Yu; Shu-Ming, Chen; Jian-Jun, Chen; Peng-Cheng, Huang; Rui-Qiang, Song

    2016-04-01

    Charge sharing is becoming an important topic as the feature size scales down in fin field-effect-transistor (FinFET) technology. However, the studies of charge sharing induced single-event transient (SET) pulse quenching with bulk FinFET are reported seldomly. Using three-dimensional technology computer aided design (3DTCAD) mixed-mode simulations, the effects of supply voltage and body-biasing on SET pulse quenching are investigated for the first time in bulk FinFET process. Research results indicate that due to an enhanced charge sharing effect, the propagating SET pulse width decreases with reducing supply voltage. Moreover, compared with reverse body-biasing (RBB), the circuit with forward body-biasing (FBB) is vulnerable to charge sharing and can effectively mitigate the propagating SET pulse width up to 53% at least. This can provide guidance for radiation-hardened bulk FinFET technology especially in low power and high performance applications. Project supported by the National Natural Science Foundation of China (Grant Nos. 61376109, 61434007, and 61176030).

  13. Single, high-dose 17β-estradiol therapy has anti-apoptotic effect and induces cerebral plasticity following transient forebrain ischemia in gerbils (Short communication).

    PubMed

    Wappler, Edina A; Gál, A; Skopál, J; Nagy, Z

    2011-06-01

    Although much is known about the protective effect of acute estrogen therapy in cerebral ischemia, relatively little is known about the importance of apoptosis and cerebral plasticity in this mechanism. In this work 10 min global cerebral ischemia was produced by transient bilateral carotid occlusion in 4-month-old ovariectomized female gerbils. In every of our experimental group (sham for ischemia group, ischemia group and ischemia + a high, single dose 17β-estradiol pre-treatment group) apoptotic (bcl-Xl, bax) and cerebral plasticity (GAP-43, synapsin-I, nestin) hippocampal genes' expression was measured four days after surgery. Expression of the anti-apoptotic bcl-Xl (p<0.01) and the cerebral plasticity marker synapsin-I and nestin (p<0.01) increased with acute estrogen pretreatment in ischemic animals. No change, however, in bax or GAP-43 expression was detected in estrogen treated animals compared to ischemic gerbils. These results suggest that acute estrogen therapy has anti-apoptotic effect and increases cerebral plasticity, which play an important role in cytoprotection or cerebroprotection. PMID:21616777

  14. Advanced development of the spectrum sciences Model 5005-TF, single-event test fixture

    SciTech Connect

    Ackermann, M.R.; Browning, J.S. ); Hughlock, B.W. ); Lum, G.K. ); Tsacoyeanes, W.C. Lab., Inc., Cambridge, MA ); Weeks, M.D. )

    1990-09-01

    This report summarizes the advanced development of the Spectrum Sciences Model 5005-TF, Single-Event Test Fixture. The Model 5005-TF uses a Californium-252 (Cf-252) fission-fragment source to test integrated circuits and other devices for the effects of single-event phenomena. Particle identification methods commonly used in high-energy physics research and nuclear engineering have been incorporated into the Model 5005-TF for estimating the particle charge, mass, and energy parameters. All single-event phenomena observed in a device under test (DUT) are correlated with an identified fission fragment, and its linear energy transfer (LET) and range in the semiconductor material of the DUT.

  15. Psychometric Characteristics of Single-Word Tests of Children's Speech Sound Production

    ERIC Educational Resources Information Center

    Flipsen, Peter, Jr.; Ogiela, Diane A.

    2015-01-01

    Purpose: Our understanding of test construction has improved since the now-classic review by McCauley and Swisher (1984) . The current review article examines the psychometric characteristics of current single-word tests of speech sound production in an attempt to determine whether our tests have improved since then. It also provides a resource

  16. 10 CFR 26.165 - Testing split specimens and retesting single specimens.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... confirmatory creatinine and confirmatory specific gravity tests, when retesting an aliquot of a single specimen or testing Bottle B of a split specimen, to reconfirm that the creatinine concentration was less than.... The second laboratory may only conduct the confirmatory creatinine and specific gravity tests...

  17. 10 CFR 26.165 - Testing split specimens and retesting single specimens.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... confirmatory creatinine and confirmatory specific gravity tests, when retesting an aliquot of a single specimen or testing Bottle B of a split specimen, to reconfirm that the creatinine concentration was less than.... The second laboratory may only conduct the confirmatory creatinine and specific gravity tests...

  18. Psychometric Characteristics of Single-Word Tests of Children's Speech Sound Production

    ERIC Educational Resources Information Center

    Flipsen, Peter, Jr.; Ogiela, Diane A.

    2015-01-01

    Purpose: Our understanding of test construction has improved since the now-classic review by McCauley and Swisher (1984) . The current review article examines the psychometric characteristics of current single-word tests of speech sound production in an attempt to determine whether our tests have improved since then. It also provides a resource…

  19. Determination of carbon fiber adhesion to thermoplastic polymers using the single fiber/matrix tensile test

    NASA Technical Reports Server (NTRS)

    Bascom, W. D.; Cordner, L. W.; Hinkley, J. L.; Johnston, N. J.

    1986-01-01

    The single fiber adhesion shear test has been adapted to testing the adhesion between carbon fiber and thermoplastic polymers. Tests of three thermoplastics, polycarbonate, polyphenylene oxide and polyetherimide indicate the shear adhesion strength is significantly less than of an epoxy polymer to the same carbon fiber.

  20. Initial Neutronics Analyses for HEU to LEU Fuel Conversion of the Transient Reactor Test Facility (TREAT) at the Idaho National Laboratory

    SciTech Connect

    Kontogeorgakos, D.; Derstine, K.; Wright, A.; Bauer, T.; Stevens, J.

    2013-06-01

    The purpose of the TREAT reactor is to generate large transient neutron pulses in test samples without over-heating the core to simulate fuel assembly accident conditions. The power transients in the present HEU core are inherently self-limiting such that the core prevents itself from overheating even in the event of a reactivity insertion accident. The objective of this study was to support the assessment of the feasibility of the TREAT core conversion based on the present reactor performance metrics and the technical specifications of the HEU core. The LEU fuel assembly studied had the same overall design, materials (UO2 particles finely dispersed in graphite) and impurities content as the HEU fuel assembly. The Monte Carlo N–Particle code (MCNP) and the point kinetics code TREKIN were used in the analyses.

  1. Compendium of Recent Test Results of Single Event Effects Conducted by the Jet Propulsion Laboratory

    NASA Technical Reports Server (NTRS)

    Allen, Gregory R.; Guertin, Steven M.; Scheick, Leif Z.; Irom, Farokh; Zajac, Stephanie

    2012-01-01

    This paper reports heavy ion, proton, and laser induced single event effects results for a variety of microelectronic devices targeted for possible use in NASA spacecrafts. The compendium covers devices tested within the years of 2010 through 2012.

  2. Single Mothers and Psychological Well-Being: A Test of the Stress and Vulnerability Hypotheses.

    ERIC Educational Resources Information Center

    McLanahan, Sara S.

    Recent studies indicate that single mothers experience unusually high levels of psychological distress. The purpose of this paper is to compare rival explanations for these high levels. Four hypotheses are tested: (1) the psychological well-being of single mothers, relative to married parents, declines over time; (2) changes in psychological…

  3. 10 CFR 26.165 - Testing split specimens and retesting single specimens.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Testing split specimens and retesting single specimens. 26.165 Section 26.165 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Laboratories... reported on a single specimen of 30 mL or more, or a specimen in Bottle A of a split specimen which...

  4. 78 FR 44189 - Petition for Modification of Single Car Air Brake Test Procedures

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ..., 2000 (65 FR 19477). Robert C. Lauby, Deputy Associate Administrator for Regulatory and Legislative... Federal Railroad Administration Petition for Modification of Single Car Air Brake Test Procedures In... the Federal Railroad Administration (FRA) per 49 CFR 232.307 to modify the single car air brake...

  5. Transient performance

    NASA Astrophysics Data System (ADS)

    Curnock, Barry

    Gas turbine engine transient behavior, that which is concerned with the changes in engine parameters during acceleration or decceleration of an engine from one steady state point to a different steady state point, is considered. An engine can also experience cyclic aerodynamic phenomena which occur at a nominally steady condition; examples are compressor rotator stall and intake or afterburner buzz. The following are discussed: certification requirements; mechanism of acceleration; compressor working lines and surge; and some important factors (pressure level, moment of inertia, heat soakage, clearances, measurement of transients, thrust reversal, and transient maneuvers which involve significant changes to the shaft speeds of the engine). A set of graphics illustrating transient performance is presented.

  6. Myelin Water Fraction Is Transiently Reduced after a Single Mild Traumatic Brain Injury - A Prospective Cohort Study in Collegiate Hockey Players.

    PubMed

    Wright, Alexander D; Jarrett, Michael; Vavasour, Irene; Shahinfard, Elham; Kolind, Shannon; van Donkelaar, Paul; Taunton, Jack; Li, David; Rauscher, Alexander

    2016-01-01

    Impact-related mild traumatic brain injuries (mTBI) are a major public health concern, and remain as one of the most poorly understood injuries in the field of neuroscience. Currently, the diagnosis and management of such injuries are based largely on patient-reported symptoms. An improved understanding of the underlying pathophysiology of mTBI is urgently needed in order to develop better diagnostic and management protocols. Specifically, dynamic post-injury changes to the myelin sheath in the human brain have not been examined, despite 'compromised white matter integrity' often being described as a consequence of mTBI. In this preliminary cohort study, myelin water imaging was used to prospectively evaluate changes in myelin water fraction, derived from the T2 decay signal, in two varsity hockey teams (45 players) over one season of athletic competition. 11 players sustained a concussion during competition, and were scanned at 72 hours, 2 weeks, and 2 months post-injury. Results demonstrated a reduction in myelin water fraction at 2 weeks post-injury in several brain areas relative to preseason scans, including the splenium of the corpus callosum, right posterior thalamic radiation, left superior corona radiata, left superior longitudinal fasciculus, and left posterior limb of the internal capsule. Myelin water fraction recovered to pre-season values by 2 months post-injury. These results may indicate transient myelin disruption following a single mTBI, with subsequent remyelination of affected neurons. Myelin disruption was not apparent in the athletes who did not experience a concussion, despite exposure to repetitive subconcussive trauma over a season of collegiate hockey. These findings may help to explain many of the metabolic and neurological deficits observed clinically following mTBI. PMID:26913900

  7. Myelin Water Fraction Is Transiently Reduced after a Single Mild Traumatic Brain Injury – A Prospective Cohort Study in Collegiate Hockey Players

    PubMed Central

    Vavasour, Irene; Shahinfard, Elham; Kolind, Shannon; van Donkelaar, Paul; Taunton, Jack; Li, David; Rauscher, Alexander

    2016-01-01

    Impact-related mild traumatic brain injuries (mTBI) are a major public health concern, and remain as one of the most poorly understood injuries in the field of neuroscience. Currently, the diagnosis and management of such injuries are based largely on patient-reported symptoms. An improved understanding of the underlying pathophysiology of mTBI is urgently needed in order to develop better diagnostic and management protocols. Specifically, dynamic post-injury changes to the myelin sheath in the human brain have not been examined, despite ‘compromised white matter integrity’ often being described as a consequence of mTBI. In this preliminary cohort study, myelin water imaging was used to prospectively evaluate changes in myelin water fraction, derived from the T2 decay signal, in two varsity hockey teams (45 players) over one season of athletic competition. 11 players sustained a concussion during competition, and were scanned at 72 hours, 2 weeks, and 2 months post-injury. Results demonstrated a reduction in myelin water fraction at 2 weeks post-injury in several brain areas relative to preseason scans, including the splenium of the corpus callosum, right posterior thalamic radiation, left superior corona radiata, left superior longitudinal fasciculus, and left posterior limb of the internal capsule. Myelin water fraction recovered to pre-season values by 2 months post-injury. These results may indicate transient myelin disruption following a single mTBI, with subsequent remyelination of affected neurons. Myelin disruption was not apparent in the athletes who did not experience a concussion, despite exposure to repetitive subconcussive trauma over a season of collegiate hockey. These findings may help to explain many of the metabolic and neurological deficits observed clinically following mTBI. PMID:26913900

  8. Status of High Power Tests of Normal Conducting Single-Cell Structures

    SciTech Connect

    Dolgashev, V.A.; Tantawi, S.G.; Higashi, Y.; Higo, T.; /KEK, Tsukuba

    2011-11-04

    We report the results of ongoing high power tests of single-cell standing wave structures. These tests are part of an experimental and theoretical study of rf breakdown in normal conducting structures at 11.4 GHz. The goal of this study is to determine the maximum gradient possibilities for normal-conducting rf powered particle beam accelerators. The test setup consists of reusable mode launchers and short test structures powered by SLACs XL-4 klystron. The mode launchers and structures were manufactured at SLAC and KEK and tested at the SLAC klystron test laboratory.

  9. First high power pulsed tests of a dressed 325 MHz superconducting single spoke resonator at Fermilab

    SciTech Connect

    Madrak, R.; Branlard, J.; Chase, B.; Darve, C.; Joireman, P.; Khabiboulline, T.; Mukherjee, A.; Nicol, T.; Peoples-Evans, E.; Peterson, D.; Pischalnikov, Y.; /Fermilab

    2011-03-01

    In the recently commissioned superconducting RF cavity test facility at Fermilab (SCTF), a 325 MHz, {beta} = 0.22 superconducting single-spoke resonator (SSR1) has been tested for the first time with its input power coupler. Previously, this cavity had been tested CW with a low power, high Q{sub ext} test coupler; first as a bare cavity in the Fermilab Vertical Test Stand and then fully dressed in the SCTF. For the tests described here, the design input coupler with Q{sub ext} {approx} 10{sup 6} was used. Pulsed power was provided by a Toshiba E3740A 2.5 MW klystron.

  10. Technical Progress Report on Single Pass Flow Through Tests of Ceramic Waste Forms for Plutonium Immobilization

    SciTech Connect

    Zhao, P; Roberts, S; Bourcier, W

    2000-12-01

    This report updates work on measurements of the dissolution rates of single-phase and multi-phase ceramic waste forms in flow-through reactors at Lawrence Livermore National Laboratory. Previous results were reported in Bourcier (1999). Two types of tests are in progress: (1) tests of baseline pyrochlore-based multiphase ceramics; and (2) tests of single-phase pyrochlore, zirconolite, and brannerite (the three phases that will contain most of the actinides). Tests of the multi-phase material are all being run at 25 C. The single-phase tests are being run at 25, 50, and 75 C. All tests are being performed at ambient pressure. The as-made bulk compositions of the ceramics are given in Table 1. The single pass flow-through test procedure [Knauss, 1986 No.140] allows the powdered ceramic to react with pH buffer solutions traveling upward vertically through the powder. Gentle rocking during the course of the experiment keeps the powder suspended and avoids clumping, and allows the system to behave as a continuously stirred reactor. For each test, a cell is loaded with approximately one gram of the appropriate size fraction of powdered ceramic and reacted with a buffer solution of the desired pH. The buffer solution compositions are given in Table 2. All the ceramics tested were cold pressed and sintered at 1350 C in air, except brannerite, which was sintered at 1350 C in a CO/CO{sub 2} gas mixture. They were then crushed, sieved, rinsed repeatedly in alcohol and distilled water, and the desired particle size fraction collected for the single pass flow-through tests (SPFT). The surface area of the ceramics measured by BET ranged from 0.1-0.35 m{sup 2}/g. The measured surface area values, average particle size, and sample weights for each ceramic test are given in the Appendices.

  11. Technical Progress Report on Single Pass Flow Through Tests of Ceramic Waste Forms for Plutonium Immobilization

    SciTech Connect

    Zhao, P.; Roberts, S.; Bourcier, W.L.

    2000-12-03

    This report updates work on measurements of the dissolution rates of single-phase and multi-phase ceramic waste forms in flow-through reactors at Lawrence Livermore National Laboratory. Previous results were reported in Bourcier (1999). Two types of tests are in progress: (1) tests of baseline pyrochlore-based multiphase ceramics; and (2) tests of single-phase pyrochlore, zirconolite, and brannerite (the three phases that will contain most of the actinides). Tests of the multi-phase material are all being run at 25 C. The single-phase tests are being run at 25, 50, and 75 C. All tests are being performed at ambient pressure. The as-made bulk compositions of the ceramics are given in Table 1. The single pass flow-through test procedure [Knauss, 1986 No.140] allows the powdered ceramic to react with pH buffer solutions traveling upward vertically through the powder. Gentle rocking during the course of the experiment keeps the powder suspended and avoids clumping, and allows the system to behave as a continuously stirred reactor. For each test, a cell is loaded with approximately one gram of the appropriate size fraction of powdered ceramic and reacted with a buffer solution of the desired pH. The buffer solution compositions are given in Table 2. All the ceramics tested were cold pressed and sintered at 1350 C in air, except brannerite, which was sintered at 1350 C in a CO/CO{sub 2} gas mixture. They were then crushed, sieved, rinsed repeatedly in alcohol and distilled water, and the desired particle size fraction collected for the single pass flow-through tests (SPFT). The surface area of the ceramics measured by BET ranged from 0.1-0.35 m{sup 2}/g. The measured surface area values, average particle size, and sample weights for each ceramic test are given in the Appendices.

  12. Role of optometry school in single day large scale school vision testing

    PubMed Central

    Anuradha, N; Ramani, Krishnakumar

    2015-01-01

    Background: School vision testing aims at identification and management of refractive errors. Large-scale school vision testing using conventional methods is time-consuming and demands a lot of chair time from the eye care professionals. A new strategy involving a school of optometry in single day large scale school vision testing is discussed. Aim: The aim was to describe a new approach of performing vision testing of school children on a large scale in a single day. Materials and Methods: A single day vision testing strategy was implemented wherein 123 members (20 teams comprising optometry students and headed by optometrists) conducted vision testing for children in 51 schools. School vision testing included basic vision screening, refraction, frame measurements, frame choice and referrals for other ocular problems. Results: A total of 12448 children were screened, among whom 420 (3.37%) were identified to have refractive errors. 28 (1.26%) children belonged to the primary, 163 to middle (9.80%), 129 (4.67%) to secondary and 100 (1.73%) to the higher secondary levels of education respectively. 265 (2.12%) children were referred for further evaluation. Conclusion: Single day large scale school vision testing can be adopted by schools of optometry to reach a higher number of children within a short span. PMID:25709271

  13. DESIGN AND PERFORMANCE OF SINGLE-WELL TRACER TESTS AT THE MOBILE SITE

    EPA Science Inventory

    Tracer tests are the most reliable field methods for obtaining information describing advection and dispersion in aquifers. The paper describes the design and performance of single-well tracer tests utilizing multilevel observation wells at a field site near Mobile, Alabama. In a...

  14. Analytical solutions for efficient interpretation of single-well push-pull tracer tests

    EPA Science Inventory

    Single-well push-pull tracer tests have been used to characterize the extent, fate, and transport of subsurface contamination. Analytical solutions provide one alternative for interpreting test results. In this work, an exact analytical solution to two-dimensional equations descr...

  15. A comparison of single-cycle versus multi-cycle proof testing strategies

    NASA Technical Reports Server (NTRS)

    Hudak, Stephen J., Jr.; Russell, Dale A.

    1988-01-01

    Proof testing was a useful supplement to conventional nondestructive evaluation (NDE) of space shuttle main engine (SSME) components. Since many of these components involve thin sections and high toughness materials, such as Inconel 718, conventional single-cycle proof test logic is not applicable due to the propensity for stable crack growth during the proof tests. Experience with five-cycle proof testing of SSME components is summarized and a framework is outlined for understanding multi-cycle proof testing using the fracture mechanics concept of a resistance curve. Extreme value statistics are also used to propose an empirical approach to compare the advantages and disadvantages of single- versus multi-cycle proof testing. The importance of the initial flaw size distribution and specimen thickness in such a comparison is also discussed.

  16. A Nuclear Interaction Model for Understanding Results of Single Event Testing with High Energy Protons

    NASA Technical Reports Server (NTRS)

    Culpepper, William X.; ONeill, Pat; Nicholson, Leonard L.

    2000-01-01

    An internuclear cascade and evaporation model has been adapted to estimate the LET spectrum generated during testing with 200 MeV protons. The model-generated heavy ion LET spectrum is compared to the heavy ion LET spectrum seen on orbit. This comparison is the basis for predicting single event failure rates from heavy ions using results from a single proton test. Of equal importance, this spectra comparison also establishes an estimate of the risk of encountering a failure mode on orbit that was not detected during proton testing. Verification of the general results of the model is presented based on experiments, individual part test results, and flight data. Acceptance of this model and its estimate of remaining risk opens the hardware verification philosophy to the consideration of radiation testing with high energy protons at the board and box level instead of the more standard method of individual part testing with low energy heavy ions.

  17. Incorporating Single-Locus Tests into Haplotype Cladistic Analysis in Case-Control Studies

    PubMed Central

    Liu, Jianfeng; Papasian, Chris; Deng, Hong-Wen

    2007-01-01

    In case-control studies, genetic associations for complex diseases may be probed either with single-locus tests or with haplotype-based tests. Although there are different views on the relative merits and preferences of the two test strategies, haplotype-based analyses are generally believed to be more powerful to detect genes with modest effects. However, a main drawback of haplotype-based association tests is the large number of distinct haplotypes, which increases the degrees of freedom for corresponding test statistics and thus reduces the statistical power. To decrease the degrees of freedom and enhance the efficiency and power of haplotype analysis, we propose an improved haplotype clustering method that is based on the haplotype cladistic analysis developed by Durrant et al. In our method, we attempt to combine the strengths of single-locus analysis and haplotype-based analysis into one single test framework. Novel in our method is that we develop a more informative haplotype similarity measurement by using p-values obtained from single-locus association tests to construct a measure of weight, which to some extent incorporates the information of disease outcomes. The weights are then used in computation of similarity measures to construct distance metrics between haplotype pairs in haplotype cladistic analysis. To assess our proposed new method, we performed simulation analyses to compare the relative performances of (1) conventional haplotype-based analysis using original haplotype, (2) single-locus allele-based analysis, (3) original haplotype cladistic analysis (CLADHC) by Durrant et al., and (4) our weighted haplotype cladistic analysis method, under different scenarios. Our weighted cladistic analysis method shows an increased statistical power and robustness, compared with the methods of haplotype cladistic analysis, single-locus test, and the traditional haplotype-based analyses. The real data analyses also show that our proposed method has practical significance in the human genetics field. PMID:17381242

  18. RECENT ADVANCES IN HIGH TEMPERATURE ELECTROLYSIS AT IDAHO NATIONAL LABORATORY: SINGLE CELL TESTS

    SciTech Connect

    X. Zhang; J. E. O'Brien; R. C. O'Brien

    2012-07-01

    An experimental investigation on the performance and durability of single solid oxide electrolysis cells (SOECs) is under way at the Idaho National Laboratory. In order to understand and mitigate the degradation issues in high temperature electrolysis, single SOECs with different configurations from several manufacturers have been evaluated for initial performance and long-term durability. A new test apparatus has been developed for single cell and small stack tests from different vendors. Single cells from Ceramatec Inc. show improved durability compared to our previous stack tests. Single cells from Materials and Systems Research Inc. (MSRI) demonstrate low degradation both in fuel cell and electrolysis modes. Single cells from Saint Gobain Advanced Materials (St. Gobain) show stable performance in fuel cell mode, but rapid degradation in the electrolysis mode. Electrolyte-electrode delamination is found to have significant impact on degradation in some cases. Enhanced bonding between electrolyte and electrode and modification of the microstructure help to mitigate degradation. Polarization scans and AC impedance measurements are performed during the tests to characterize the cell performance and degradation.

  19. Space Power Facility-Capabilities for Space Environmental Testing Within a Single Facility

    NASA Technical Reports Server (NTRS)

    Sorge, Richard N.

    2013-01-01

    The purpose of this paper is to describe the current and near-term environmental test capabilities of the NASA Glenn Research Center's Space Power Facility (SPF) located at Sandusky, Ohio. The paper will present current and near-term capabilities for conducting electromagnetic interference and compatibility testing, base-shake sinusoidal vibration testing, reverberant acoustic testing, and thermal-vacuum testing. The paper will also present modes of transportation, handling, ambient environments, and operations within the facility to conduct those tests. The SPF is in the midst of completing and activating new or refurbished capabilities which, when completed, will provide the ability to conduct most or all required full-scale end-assembly space simulation tests at a single test location. It is envisioned that the capabilities will allow a customer to perform a wide range of space simulation tests in one facility at reasonable cost.

  20. Non-invasive prenatal testing for single gene disorders: exploring the ethics

    PubMed Central

    Deans, Zuzana; Hill, Melissa; Chitty, Lyn S; Lewis, Celine

    2013-01-01

    Non-invasive prenatal testing for single gene disorders is now clearly on the horizon. This new technology offers obvious clinical benefits such as safe testing early in pregnancy. Before widespread implementation, it is important to consider the possible ethical implications. Four hypothetical scenarios are presented that highlight how ethical ideals of respect for autonomy, privacy and fairness may come into play when offering non-invasive prenatal testing for single gene disorders. The first scenario illustrates the moral case for using these tests for ‘information only', identifying a potential conflict between larger numbers of women seeking the benefits of the test and the wider social impact of funding tests that do not offer immediate clinical benefit. The second scenario shows how the simplicity and safety of non-invasive prenatal testing could lead to more autonomous decision-making and, conversely, how this could also lead to increased pressure on women to take up testing. In the third scenario we show how, unless strong safeguards are put in place, offering non-invasive prenatal testing could be subject to routinisation with informed consent undermined and that woman who are newly diagnosed as carriers may be particularly vulnerable. The final scenario introduces the possibility of a conflict of the moral rights of a woman and her partner through testing for single gene disorders. This analysis informs our understanding of the potential impacts of non-invasive prenatal testing for single gene disorders on clinical practice and has implications for future policy and guidelines for prenatal care. PMID:23188047

  1. LUNAR OUTGASSING, TRANSIENT PHENOMENA, AND THE RETURN TO THE MOON. II. PREDICTIONS AND TESTS FOR OUTGASSING/REGOLITH INTERACTIONS

    SciTech Connect

    Crotts, Arlin P. S.; Hummels, Cameron

    2009-12-20

    We follow Paper I with predictions of how gas leaking through the lunar surface could influence the regolith, as might be observed via optical transient lunar phenomena (TLPs) and related effects. We touch on several processes, but concentrate on low and high flow rate extremes, which are perhaps the most likely. We model explosive outgassing for the smallest gas overpressure at the regolith base that releases the regolith plug above it. This disturbance's timescale and affected area are consistent with observed TLPs; we also discuss other effects. For slow flow, escape through the regolith is prolonged by low diffusivity. Water, found recently in deep magma samples, is unique among candidate volatiles, capable of freezing between the regolith base and surface, especially near the lunar poles. For major outgassing sites, we consider the possible accumulation of water ice. Over geological time, ice accumulation can evolve downward through the regolith. Depending on gases additional to water, regolith diffusivity might be suppressed chemically, blocking seepage and forcing the ice zone to expand to larger areas, up to km{sup 2} scales, again, particularly at high latitudes. We propose an empirical path forward, wherein current and forthcoming technologies provide controlled, sensitive probes of outgassing. The optical transient/outgassing connection, addressed via Earth-based remote sensing, suggests imaging and/or spectroscopy, but aspects of lunar outgassing might be more covert, as indicated above. TLPs betray some outgassing, but does outgassing necessarily produce TLPs? We also suggest more intrusive techniques from radar to in situ probes. Understanding lunar volatiles seems promising in terms of resource exploitation for human exploration of the Moon and beyond, and offers interesting scientific goals in its own right. Many of these approaches should be practiced in a pristine lunar atmosphere, before significant confusing signals likely to be produced upon humans returning to the Moon.

  2. Lunar Outgassing, Transient Phenomena, and the Return to the Moon. II. Predictions and Tests for Outgassing/Regolith Interactions

    NASA Astrophysics Data System (ADS)

    Crotts, Arlin P. S.; Hummels, Cameron

    2009-12-01

    We follow Paper I with predictions of how gas leaking through the lunar surface could influence the regolith, as might be observed via optical transient lunar phenomena (TLPs) and related effects. We touch on several processes, but concentrate on low and high flow rate extremes, which are perhaps the most likely. We model explosive outgassing for the smallest gas overpressure at the regolith base that releases the regolith plug above it. This disturbance's timescale and affected area are consistent with observed TLPs; we also discuss other effects. For slow flow, escape through the regolith is prolonged by low diffusivity. Water, found recently in deep magma samples, is unique among candidate volatiles, capable of freezing between the regolith base and surface, especially near the lunar poles. For major outgassing sites, we consider the possible accumulation of water ice. Over geological time, ice accumulation can evolve downward through the regolith. Depending on gases additional to water, regolith diffusivity might be suppressed chemically, blocking seepage and forcing the ice zone to expand to larger areas, up to km2 scales, again, particularly at high latitudes. We propose an empirical path forward, wherein current and forthcoming technologies provide controlled, sensitive probes of outgassing. The optical transient/outgassing connection, addressed via Earth-based remote sensing, suggests imaging and/or spectroscopy, but aspects of lunar outgassing might be more covert, as indicated above. TLPs betray some outgassing, but does outgassing necessarily produce TLPs? We also suggest more intrusive techniques from radar to in situ probes. Understanding lunar volatiles seems promising in terms of resource exploitation for human exploration of the Moon and beyond, and offers interesting scientific goals in its own right. Many of these approaches should be practiced in a pristine lunar atmosphere, before significant confusing signals likely to be produced upon humans returning to the Moon.

  3. Single event upset susceptibility testing of the Xilinx Virtex II FPGA

    NASA Technical Reports Server (NTRS)

    Yui, C.; Swift, G.; Carmichael, C.

    2002-01-01

    Heavy ion testing of the Xilinx Virtex IZ was conducted on the configuration, block RAM and user flip flop cells to determine their single event upset susceptibility using LETs of 1.2 to 60 MeVcm^2/mg. A software program specifically designed to count errors in the FPGA is used to reveal L1/e values and single-event-functional interrupt failures.

  4. Comparative Performance of Four Single Extreme Outlier Discordancy Tests from Monte Carlo Simulations

    PubMed Central

    Díaz-González, Lorena; Quiroz-Ruiz, Alfredo

    2014-01-01

    Using highly precise and accurate Monte Carlo simulations of 20,000,000 replications and 102 independent simulation experiments with extremely low simulation errors and total uncertainties, we evaluated the performance of four single outlier discordancy tests (Grubbs test N2, Dixon test N8, skewness test N14, and kurtosis test N15) for normal samples of sizes 5 to 20. Statistical contaminations of a single observation resulting from parameters called δ from ±0.1 up to ±20 for modeling the slippage of central tendency or ε from ±1.1 up to ±200 for slippage of dispersion, as well as no contamination (δ = 0 and ε = ±1), were simulated. Because of the use of precise and accurate random and normally distributed simulated data, very large replications, and a large number of independent experiments, this paper presents a novel approach for precise and accurate estimations of power functions of four popular discordancy tests and, therefore, should not be considered as a simple simulation exercise unrelated to probability and statistics. From both criteria of the Power of Test proposed by Hayes and Kinsella and the Test Performance Criterion of Barnett and Lewis, Dixon test N8 performs less well than the other three tests. The overall performance of these four tests could be summarized as N2≅N15 > N14 > N8. PMID:24737992

  5. Comparative performance of four single extreme outlier discordancy tests from Monte Carlo simulations.

    PubMed

    Verma, Surendra P; Díaz-González, Lorena; Rosales-Rivera, Mauricio; Quiroz-Ruiz, Alfredo

    2014-01-01

    Using highly precise and accurate Monte Carlo simulations of 20,000,000 replications and 102 independent simulation experiments with extremely low simulation errors and total uncertainties, we evaluated the performance of four single outlier discordancy tests (Grubbs test N2, Dixon test N8, skewness test N14, and kurtosis test N15) for normal samples of sizes 5 to 20. Statistical contaminations of a single observation resulting from parameters called δ from ±0.1 up to ±20 for modeling the slippage of central tendency or ε from ±1.1 up to ±200 for slippage of dispersion, as well as no contamination (δ = 0 and ε = ±1), were simulated. Because of the use of precise and accurate random and normally distributed simulated data, very large replications, and a large number of independent experiments, this paper presents a novel approach for precise and accurate estimations of power functions of four popular discordancy tests and, therefore, should not be considered as a simple simulation exercise unrelated to probability and statistics. From both criteria of the Power of Test proposed by Hayes and Kinsella and the Test Performance Criterion of Barnett and Lewis, Dixon test N8 performs less well than the other three tests. The overall performance of these four tests could be summarized as N2≅N15 > N14 > N8. PMID:24737992

  6. Ambiguity in measuring matrix diffusion with single-well injection/recovery tracer tests

    USGS Publications Warehouse

    Lessoff, S.C.; Konikow, L.F.

    1997-01-01

    Single-well injection/recovery tracer tests are considered for use in characterizing and quantifying matrix diffusion in dual-porosity aquifers. Numerical modeling indicates that neither regional drift in homogeneous aquifers, nor heterogeneity in aquifers having no regional drift, nor hydrodynamic dispersion significantly affects these tests. However, when drift is coupled simultaneously with heterogeneity, they can have significant confounding effects on tracer return. This synergistic effect of drift and heterogeneity may help explain irreversible flow and inconsistent results sometimes encountered in previous single-well injection/recovery tracer tests. Numerical results indicate that in a hypothetical single-well injection/recovery tracer test designed to demonstrate and measure dual-porosity characteristics in a fractured dolomite, the simultaneous effects of drift and heterogeneity sometimes yields responses similar to those anticipated in a homogeneous dual-porosity formation. In these cases, tracer recovery could provide a false indication of the occurrence of matrix diffusion. Shortening the shut-in period between injection and recovery periods may make the test less sensitive to drift. Using multiple tracers having different diffusion characteristics, multiple tests having different pumping schedules, and testing the formation at more than one location would decrease the ambiguity in the interpretation of test data.

  7. Crash tests of three identical low-wing single-engine airplane

    NASA Technical Reports Server (NTRS)

    Castle, C. B.; Alfaro-Bou, E.

    1983-01-01

    Three identical four place, low wing single engine airplane specimens with nominal masses of 1043 kg were crash tested under controlled free flight conditions. The tests were conducted at the same nominal velocity of 25 m/sec along the flight path. Two airplanes were crashed on a concrete surface (at 10 and 30 deg pitch angles), and one was crashed on soil (at a -30 deg pitch angle). The three tests revealed that the specimen in the -30 deg test on soil sustained massive structural damage in the engine compartment and fire wall. Also, the highest longitudinal cabin floor accelerations occurred in this test. Severe damage, but of lesser magnitude, occurred in the -30 deg test on concrete. The highest normal cabin floor accelerations occurred in this test. The least structural damage and lowest accelerations occurred in the 10 deg test on concrete.

  8. Syncope or seizure? The diagnostic value of synchronous tilt testing and video-EEG monitoring in children with transient loss of consciousness.

    PubMed

    Yilmaz, S; Gökben, S; Levent, E; Serdaroğlu, G; Özyürek, R

    2012-05-01

    Syncope and seizure are frequently encountered problems in daily neurology practice, and they also share common findings such as transient loss of consciousness and atonia. Sometimes, it is difficult to make a differentiation between the two entities using only clinical findings. In this study, nineteen patients aged between 5 and 20 years who had recurrent transient loss of consciousness and occasional atonic events were examined with synchronous tilt testing and video-EEG recordings. Eleven patients were initially diagnosed with epilepsy, and they were given antiepileptic drugs. Eight patients displayed neurally mediated syncope during examination. Four of the eight patients had cardioinhibitory syncope type 2B. Three-fourths of the patients with syncope had been initially diagnosed with epilepsy and were prescribed antiepileptic drugs. One patient with cardioinhibitory syncope who had prolonged asystole and frequent attacks needed a cardiac pacemaker. Following implantation, she had no new attacks. Synchronous tilt testing and video-EEG recordings give more information than doing them separately, and they are helpful in the differential diagnosis of syncope and seizure. PMID:22459868

  9. MULTIMOMENT RADIO TRANSIENT DETECTION

    SciTech Connect

    Spitler, L. G.; Cordes, J. M.; Chatterjee, S.; Stone, J.

    2012-04-01

    We present a multimoment technique for signal classification and apply it to the detection of fast radio transients in incoherently dedispersed data. Specifically, we define a spectral modulation index in terms of the fractional variation in intensity across a spectrum. A signal whose intensity is distributed evenly across the entire band has a lower modulation index than a spectrum whose intensity is localized in a single channel. We are interested in broadband pulses and use the modulation index to excise narrowband radio frequency interference by applying a modulation index threshold above which candidate events are removed. The technique is tested both with simulations and using data from known sources of radio pulses (RRAT J1928+15 and giant pulses from the Crab pulsar). The method is generalized to coherent dedispersion, image cubes, and astrophysical narrowband signals that are steady in time. We suggest that the modulation index, along with other statistics using higher order moments, should be incorporated into signal detection pipelines to characterize and classify signals.

  10. Multimoment Radio Transient Detection

    NASA Astrophysics Data System (ADS)

    Spitler, L. G.; Cordes, J. M.; Chatterjee, S.; Stone, J.

    2012-04-01

    We present a multimoment technique for signal classification and apply it to the detection of fast radio transients in incoherently dedispersed data. Specifically, we define a spectral modulation index in terms of the fractional variation in intensity across a spectrum. A signal whose intensity is distributed evenly across the entire band has a lower modulation index than a spectrum whose intensity is localized in a single channel. We are interested in broadband pulses and use the modulation index to excise narrowband radio frequency interference by applying a modulation index threshold above which candidate events are removed. The technique is tested both with simulations and using data from known sources of radio pulses (RRAT J1928+15 and giant pulses from the Crab pulsar). The method is generalized to coherent dedispersion, image cubes, and astrophysical narrowband signals that are steady in time. We suggest that the modulation index, along with other statistics using higher order moments, should be incorporated into signal detection pipelines to characterize and classify signals.

  11. Columbia University flow instability experimental program: Volume 7. Single tube tests, critical heat flux test program

    SciTech Connect

    Dougherty, T.; Maciuca, C.; McAssey, E.V. Jr.; Reddy, D.G.; Yang, B.W.

    1992-09-01

    This report deals with critical heat flux (CHF) measurements in vertical down flow of water at low pressures in a round Inconel tube, 96 inches long and 0.62 inch inside diameter. A total of 28 CHF points were obtained. These data were found to correlate linearly with the single variable q, defined as the heat flux required to raise the enthalpy from the inlet value to the saturation value. These results were compared to the published results of Swedish investigators for vertical upflow of water at low pressures in round tubes of similar diameters and various lengths. The parameter q depends on the inlet enthalpy and is a nonlocal variable, thus this correlation is nonlocal unless the coefficients depend upon tube length in a particular prescribed manner. For the low pressure Swedish data, the coefficients are practically independent of length and hence the correlation is nonlocal. In the present investigation only one length was employed, so it is not possible to determine whether the correlation for these data is local or nonlocal, although there is reason to believe that it is local. The same correlation was applied to a large data base (thousands of CHF points) compiled from the published data of a number of groups and found to apply, with reasonable accuracy over a wide range of conditions, yielding sometimes local and sometimes nonlocal correlations. The basic philosophy of data analysis here was not to generate a single correlation which would reproduce all data, but to search for correlations which apply adequately over some range and which might have some mechanistic significance. The tentative conclusion is that at least two mechanisms appear operative, leading to two types of correlations, one local, the other nonlocal.

  12. Numerical simulation of combined natural and forced convection during thermal-hydraulic transients. [LMFBR

    SciTech Connect

    Domanus, H.M.; Sha, W.T.

    1981-01-01

    The single-phase COMMIX (COMponent MIXing) computer code performs fully three-dimensional, transient, thermal-hydraulic analyses of liquid-sodium LMFBR components. It solves the conservation equations of mass, momentum, and energy as a boundary-value problem in space and as an initial-value problem in time. The concepts of volume porosity, surface permeability and distributed resistance, and heat source have been employed in quasi-continuum (rod-bundle) applications. Results from three transient simulations involving forced and natural convection are presented: (1) a sodium-filled horizontal pipe initially of uniform temperature undergoing an inlet velocity rundown transient, as well as an inlet temperature transient; (2) a 19-pin LMFBR rod bundle undergoing a velocity transient; and, (3) a simulation of a water test of a 1/10-scale outlet plenum undergoing both velocity and temperature transients.

  13. In-flight and ground testing of single event upset sensitivity in static RAMs

    SciTech Connect

    Johansson, K.; Dyreklev, P.; Granbom, B.; Calvet, C.; Fourtine, S.; Feuillatre, O.

    1998-06-01

    This paper presents the results from in-flight measurements of single event upsets (SEU) in static random access memories (SRAM) caused by the atmospheric radiation environment at aircraft altitudes. The memory devices were carried on commercial airlines at high altitude and mainly high latitudes. The SEUs were monitored by a Component Upset Test Equipment (CUTE), designed for this experiment. The in flight results are compared to ground based testing with neutrons from three different sources.

  14. Testing Landscape Theory for Biomolecular Processes with Single Molecule Fluorescence Spectroscopy

    NASA Astrophysics Data System (ADS)

    Truex, Katherine; Chung, Hoi Sung; Louis, John M.; Eaton, William A.

    2015-07-01

    Although Kramers' theory for diffusive barrier crossing on a 1D free energy profile plays a central role in landscape theory for complex biomolecular processes, it has not yet been rigorously tested by experiment. Here we test this 1D diffusion scenario with single molecule fluorescence measurements of DNA hairpin folding. We find an upper bound of 2.5 μ s for the average transition path time, consistent with the predictions by theory with parameters determined from optical tweezer measurements.

  15. Ca transients in cardiac myocytes measured with a low affinity fluorescent indicator, furaptra.

    PubMed Central

    Konishi, M; Berlin, J R

    1993-01-01

    Intracellular calcium ion ([Ca2+]i) transients were measured in single rat ventricular myocytes with the fluorescent indicator furaptra. Cells were voltage clamped with a single patch electrode containing the K+ salt of furaptra and fluorescence at 500 nm was measured during illumination with 350 and 370 nm light. Depolarizing voltage-clamp pulses elicited [Ca2+]-dependent fluorescent transients in 30 of 33 cells tested. The peak change in [Ca2+]i elicited by 50-ms depolarizations from -70 to +10 mV was 1.52 +/- 0.25 microM (mean +/- SEM, n = 7). The size of the [Ca2+]i transient increased in response to 10 microM isoproterenol, prolongation of the depolarization, and increasing pipette [Na+]. Because furaptra is sensitive to Ca2+ and Mg2+, changes in [Mg2+]i during the [Ca2+]i transient could not be measured. Instead, a single-compartment model was developed to simulate changes in [Mg2+] during [Ca2+] transients. The simulations predicted that a 2 microM [Ca2+] transient was accompanied by a slow increase in [Mg2+] (14-29 microM), which became larger as basal [Mg2+] increased (0.5-2.0 mM). The [Mg2+] transient reached a peak approximately 1 s after the peak of the [Ca2+] transient with the slow changes in [Mg2+] dominated by competition at the Ca2+/Mg2+ sites of Troponin. These changes in [Mg2+], however, were so small and slow that they were unlikely to affect the furaptra fluorescence signal at the peak of the [Ca2+]i transient. The [Ca2+]i transient reported by furaptra appears to be larger than that reported by other Ca2+ indicators; however, we conclude this larger transient is at least as accurate as [Ca2+]i transients reported by the other indicators. PMID:8494988

  16. Strategies for analyzing nerve conduction data: superiority of a summary index over single tests.

    PubMed

    Robinson, L R; Micklesen, P J; Wang, L

    1998-09-01

    We compared three strategies for diagnosing carpal tunnel syndrome: using a single test; requiring one, two, or three of three tests to be abnormal; or utilizing a single summary variable incorporating data from three tests. Sixty-five hands of subjects without clinical carpal tunnel syndrome (CTS) were compared with 66 hands with clinical CTS. Three latency differences were measured: median-ulnar (8 cm) midpalmar orthodromic (palmdiff); median-ulnar ring finger (14 cm) antidromic (ringdiff); and median-radial thumb (10 cm) antidromic (thumbdiff). The combined sensory index (CSI) was the sum of these three differences. Sensitivity for the tests was palmdiff 69.7%, ringdiff 74.2%, thumbdiff 75.8%, and CSI 83.1%. Specificity was 95.4-96.9%. Requiring one, two, or three of three tests to be abnormal yielded sensitivities of 84.8%, 74.2%, or 56.1%, respectively, but specificities of 92.3%, 98.5%, and 100%, respectively. We conclude that a combined index improves diagnostic classification over use of single test results. PMID:9703442

  17. The characterization of carbon nanotube infused glass fibers by single filament fragmentation test methods

    NASA Astrophysics Data System (ADS)

    Roach, Andrew Michael

    Single filament fragmentation tests were completed for individual glass fibers with varying surface treatments and carbon nanostructure infusions. Fiber fragmentation was analyzed by embedding a single filament into a standard tensile interface, which provided shear stress transfer between a conventional epoxy resin system and the constituent filament. Established single filament fragmentation techniques were used to characterize fiber and interface properties. A novel method of comparing fibers is introduced by correlating bundle tow test results to fiber fragmentation critical length data to qualitatively relate fiber performance. Photoelastic birefringent stress fringes were processed at select fiber fragmentation locations to further characterize the fiber-resin, or fiber-carbon nanostructure-resin, interface. Overall, the performance matrix qualitative comparison method, coupled with stress fringe analysis, proved to be an effective means of qualitatively evaluating fiber and processing parameters, and efficiently identifies the most fruitful path forward for optimized fiber development.

  18. Use of the single-breath method of estimating cardiac output during exercise-stress testing.

    NASA Technical Reports Server (NTRS)

    Buderer, M. C.; Rummel, J. A.; Sawin, C. F.; Mauldin, D. G.

    1973-01-01

    The single-breath cardiac output measurement technique of Kim et al. (1966) has been modified for use in obtaining cardiac output measurements during exercise-stress tests on Apollo astronauts. The modifications involve the use of a respiratory mass spectrometer for data acquisition and a digital computer program for data analysis. The variation of the modified method for triplicate steady-state cardiac output measurements was plus or minus 1 liter/min. The combined physiological and methodological variation seen during a set of three exercise tests on a series of subjects was 1 to 2.5 liter/min. Comparison of the modified method with the direct Fick technique showed that although the single-breath values were consistently low, the scatter of data was small and the correlation between the two methods was high. Possible reasons for the low single-breath cardiac output values are discussed.

  19. Initial Comparison of Single Cylinder Stirling Engine Computer Model Predictions with Test Results

    NASA Technical Reports Server (NTRS)

    Tew, R. C., Jr.; Thieme, L. G.; Miao, D.

    1979-01-01

    A Stirling engine digital computer model developed at NASA Lewis Research Center was configured to predict the performance of the GPU-3 single-cylinder rhombic drive engine. Revisions to the basic equations and assumptions are discussed. Model predictions with the early results of the Lewis Research Center GPU-3 tests are compared.

  20. Hydraulic fracture growth during steam stimulation in a single-well test

    SciTech Connect

    Holzhausen, G.R.; Card, C.C.; Dobecki, T.L.; Raisbeck, J.M.

    1985-03-01

    Ground deformation was monitored for nearly ten weeks during the first cycle of steam stimulation in a single-well test using an array of high-resolution borehole tiltmeters. Ground response indicated that steam injection was not a continuous process, but rather was characterized by numerous episodic events. The magnitudes of the pressure and deformation changes varied from event to event, apparently unsystematically.

  1. ANALYSIS AND INTERPRETATION OF SINGLE-WELL TRACER TESTS IN STRATIFIED AQUIFERS

    EPA Science Inventory

    The study deals with the definition and measurement of the dispersive properties of aquifers. Knowledge of such dispersive properties are of fundamental importance to the evaluation, analysis, and simulation of contaminant migration in groundwater. In the single-well test describ...

  2. The effectiveness of combined gripping method in tensile testing of UHMWPE single yarn

    NASA Astrophysics Data System (ADS)

    Wang, H. X.; Hazell, P. J.; Shankar, K.; Morozov, E. V.; Escobedo, J. P.

    2015-07-01

    This paper presents the experimental study on the effectiveness of combined gripping method employed in the tensile testing of UHMWPE (Dyneema® SK75) single yarn. Seven different solutions including epoxy, acrylic, and ethyl cyanoacrylate adhesives were tested under quasi-static loadings in order to determine the most effective adhesive for bonding UHMWPE single yarn to aluminium sheets. The ethyl cyanoacrylate adhesive combined with polyolefin surface primer was found to be the best choice which could prevent yarn slippage and ensure the failure of yarn occurs in the gauge section. The single yarns were then tested at three strain rates of 3.3×10-5, 3.3×10-3, and 0.33 s-1. The tensile strength, maximum strain, and Young's modulus were determined from the measured stress-strain curves and compared with the values from literature; the results showed these tensile properties of single yarn depend on strain rate over the range tested.

  3. 76 FR 34801 - Petition for Modification of Single Car Air Brake Test Procedures

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Federal Railroad Administration Petition for Modification of Single Car Air Brake Test Procedures In accordance with Part 232 of Title 49 of the Code of Federal Regulations (CFR), this document provides the public notice that by a document...

  4. Guideline for heavy ion radiation testing for Single Event Upset (SEU)

    SciTech Connect

    Nichols, D.K.; Price, W.E.; Malone, C.

    1984-01-01

    A guideline for heavy ion radiation testing for single event upset was prepared to assist new experimenters in preparing and directing tests. How to estimate parts vulnerability and select an irradiation facility is described. A broad brush description of JPL equipment is given, certain necessary pre-test procedures are outlined and the roles and testing guidelines for on-site test personnel are indicated. Detailed descriptions of equipment needed to interface with JPL test crew and equipment are not provided, nor does it meet the more generalized and broader requirements of a MIL-STD document. A detailed equipment description is available upon request, and a MIL-STD document is in the early stages of preparation.

  5. A guideline for heavy ion radiation testing for Single Event Upset (SEU)

    NASA Technical Reports Server (NTRS)

    Nichols, D. K.; Price, W. E.; Malone, C.

    1984-01-01

    A guideline for heavy ion radiation testing for single event upset was prepared to assist new experimenters in preparing and directing tests. How to estimate parts vulnerability and select an irradiation facility is described. A broad brush description of JPL equipment is given, certain necessary pre-test procedures are outlined and the roles and testing guidelines for on-site test personnel are indicated. Detailed descriptions of equipment needed to interface with JPL test crew and equipment are not provided, nor does it meet the more generalized and broader requirements of a MIL-STD document. A detailed equipment description is available upon request, and a MIL-STD document is in the early stages of preparation.

  6. Single-leg hop testing following fatiguing exercise: reliability and biomechanical analysis.

    PubMed

    Augustsson, J; Thomeé, R; Lindén, C; Folkesson, M; Tranberg, R; Karlsson, J

    2006-04-01

    A fatiguing exercise protocol was combined with single-leg hop testing to improve the possibilities of evaluating the effects of training or rehabilitation interventions. In the first test-retest experiment, 11 healthy male subjects performed two trials of single-leg hops under three different test conditions: non-fatigued and following fatiguing exercise, which consisted of unilateral weight machine knee extensions at 80% and 50%, respectively, of 1 repetition maximum (1 RM) strength. Intraclass correlation coefficients ranged from 0.75 to 0.98 for different hop test conditions, indicating that all tests were reliable. For the second experiment, eight healthy male subjects performed the fatiguing exercise protocol to investigate how fatigue influences lower-extremity joint kinematics and kinetics during single-leg hops. Hip, knee and ankle joint angles, moments and powers, as well as ground-reaction forces were recorded with a six-camera, motion-capture system and a force platform. Recovery of hop performance following the fatiguing exercise was also measured. During the take-off for the single-leg hops, hip and knee flexion angles, generated powers for the knee and ankle joints, and ground-reaction forces decreased for the fatigued hop conditions compared with the non-fatigued condition (P<0.05). Compared with landing during the non-fatigued condition, hip moments and ground-reaction forces were lower for the fatigued hop conditions (P<0.05). The negative joint power was two to three times greater for the knee than for the hip and five to 10 times greater for the knee than for the ankle during landing for all test conditions (P<0.05). Most measured variables had recovered three minutes post-exercise. It is concluded that the fatiguing exercise protocol combined with single-leg hop testing was a reliable method for investigating functional performance under fatigued test conditions. Further, subjects utilized an adapted hop strategy, which employed less hip and knee flexion and generated powers for the knee and ankle joints during take-off, and less hip joint moments during landing under fatigued conditions. The large negative power values observed at the knee joint during the landing phase of the single-leg hop, during which the quadriceps muscle activates eccentrically, indicate that not only hop distance but also the ability to perform successful landings should be investigated when assessing dynamic knee function. PMID:16533349

  7. Tank selection for Light Duty Utility Arm (LDUA) system hot testing in a single shell tank

    SciTech Connect

    Bhatia, P.K.

    1995-01-31

    The purpose of this report is to recommend a single shell tank in which to hot test the Light Duty Utility Arm (LDUA) for the Tank Waste Remediation System (TWRS) in Fiscal Year 1996. The LDUA is designed to utilize a 12 inch riser. During hot testing, the LDUA will deploy two end effectors (a High Resolution Stereoscopic Video Camera System and a Still/Stereo Photography System mounted on the end of the arm`s tool interface plate). In addition, three other systems (an Overview Video System, an Overview Stereo Video System, and a Topographic Mapping System) will be independently deployed and tested through 4 inch risers.

  8. First high gradient test results of a dressed 325 MHz superconducting single spoke resonator at Fermilab

    SciTech Connect

    Webber, R.C.; Khabiboulline, T.; Madrak, R.; Nicol, T.; Ristori, L.; Soyars, W.; Wagner, R.; /Fermilab

    2010-09-01

    A new superconducting RF cavity test facility has been commissioned at Fermilab in conjunction with first tests of a 325 MHz, {beta} = 0.22 superconducting single-spoke cavity dressed with a helium jacket and prototype tuner. The facility is described and results of full gradient, CW cavity tests with a high Q{sub ext} drive coupler are reported. Sensitivities to Q disease and externally applied magnetic fields were investigated. Results are compared to bare cavity results obtained prior to hydrogen degassing and welding into the helium jacket.

  9. Analytical solutions for efficient interpretation of single-well push-pull tracer tests

    NASA Astrophysics Data System (ADS)

    Huang, Junqi; Christ, John A.; Goltz, Mark N.

    2010-08-01

    Single-well push-pull tracer tests have been used to characterize the extent, fate, and transport of subsurface contamination. Analytical solutions provide one alternative for interpreting test results. In this work, an exact analytical solution to two-dimensional equations describing the governing processes acting on a dissolved compound during a modified push-pull test (advection, longitudinal and transverse dispersion, first-order decay, and rate-limited sorption/partitioning in steady, divergent, and convergent flow fields) is developed. The coupling of this solution with inverse modeling to estimate aquifer parameters provides an efficient methodology for subsurface characterization. Synthetic data for single-well push-pull tests are employed to demonstrate the utility of the solution for determining (1) estimates of aquifer longitudinal and transverse dispersivities, (2) sorption distribution coefficients and rate constants, and (3) non-aqueous phase liquid (NAPL) saturations. Employment of the solution to estimate NAPL saturations based on partitioning and non-partitioning tracers is designed to overcome limitations of previous efforts by including rate-limited mass transfer. This solution provides a new tool for use by practitioners when interpreting single-well push-pull test results.

  10. Single-well interference slug tests to assess the vertical hydraulic conductivity of unconsolidated aquifers

    NASA Astrophysics Data System (ADS)

    Paradis, Daniel; Lefebvre, René

    2013-01-01

    SummaryMeaningful understanding of flow and solute transport in general requires the knowledge of hydraulic conductivity and its anisotropy. Various field methods allow the measurement of the horizontal component (Kh), but vertical hydraulic conductivity (Kv) is rarely measured, for lack of practical field tests. This paper proposes vertical interference slug tests, an adaptation of inter-well interference slug tests to a single well, for the efficient field measurement of Kv. The test is carried out in a single well between a stress and an observation interval that are vertically isolated with a three-packer assembly. An instantaneous pressure pulse is induced in the stress interval and resulting drawdowns are recorded in both the stress and the observation intervals. In a proof-of-concept field study, 12 vertical interference tests were carried out sequentially along a fully-screened well across a moderately heterogeneous and highly anisotropic aquifer made up of littoral silts and sands. A direct-push method was used to install the well, which was completed without sand-pack to allow the natural collapse of sediments in the thin annular space around the screen. Direct-push wells allow the measurement of in situ hydraulic properties of sediments and minimize well construction interferences with hydraulic tests. Drawdowns measured in stress and observation intervals of multiple tests were simultaneously inverted numerically to reconstruct heterogeneous profiles of Kh, hydraulic conductivity anisotropy (Kv/Kh), and specific storage (Ss). Results were validated by comparison of observed versus predicted drawdowns and with field and laboratory measurements of Kh and Kv made along the tested well. Results indicate that the profile of Kv values obtained with vertical interference slug tests follows a similar pattern with depth than the profile with lab measurements made with a permeameter on soil samples collected in the same intervals as the interference tests, which demonstrates that vertical interference slug tests could provide an efficient method for the field measurement of well-scale Kv values.

  11. Microsample testing of single crystalline Ti-52 at% Al and Ti-55.5 at% Al

    SciTech Connect

    Zupan, M.; Dimiduk, D.M.; Hemker, K.J.

    1999-07-01

    Dislocation activity in two-phase commercial TiAl alloys occurs most readily in the {gamma}-TiAl phase, and measurements of the CRSS of single crystalline {gamma}-TiAl provides a solid foundation for understanding the mechanical performance of these alloys. Single crystals of {gamma}-TiAl with greater than 54.5 at% Al have been grown using the optical float zone crystal growing technique, but single crystals with lower Al content, closer to that of commercial alloys, have not. In the present study, polycrystalline ingots of Ti-52 at% Al have been heat treated to form very large grains, and microsample tensile specimens, which have a nominal gage cross-section of 250{micro}m x 300{micro}m, a gage length of 250{micro}m and an overall length of 3 mm, have been machined from within single grains. Microsample high-temperature stress-strain curves for Ti-55.5 at% Al single crystals oriented along the [001] and [010] are presented. Tensile test results for Ti-52 at% Al tested at 1,073K along the[{bar 2}37], [{bar 1}73] and [{bar 3}44] orientations will also be discussed.

  12. Statistical searches for microlensing events in large, non-uniformly sampled time-domain surveys: A test using palomar transient factory data

    SciTech Connect

    Price-Whelan, Adrian M.; Agüeros, Marcel A.; Fournier, Amanda P.; Street, Rachel; Ofek, Eran O.; Covey, Kevin R.; Levitan, David; Sesar, Branimir; Laher, Russ R.; Surace, Jason

    2014-01-20

    Many photometric time-domain surveys are driven by specific goals, such as searches for supernovae or transiting exoplanets, which set the cadence with which fields are re-imaged. In the case of the Palomar Transient Factory (PTF), several sub-surveys are conducted in parallel, leading to non-uniform sampling over its ∼20,000 deg{sup 2} footprint. While the median 7.26 deg{sup 2} PTF field has been imaged ∼40 times in the R band, ∼2300 deg{sup 2} have been observed >100 times. We use PTF data to study the trade off between searching for microlensing events in a survey whose footprint is much larger than that of typical microlensing searches, but with far-from-optimal time sampling. To examine the probability that microlensing events can be recovered in these data, we test statistics used on uniformly sampled data to identify variables and transients. We find that the von Neumann ratio performs best for identifying simulated microlensing events in our data. We develop a selection method using this statistic and apply it to data from fields with >10 R-band observations, 1.1 × 10{sup 9} light curves, uncovering three candidate microlensing events. We lack simultaneous, multi-color photometry to confirm these as microlensing events. However, their number is consistent with predictions for the event rate in the PTF footprint over the survey's three years of operations, as estimated from near-field microlensing models. This work can help constrain all-sky event rate predictions and tests microlensing signal recovery in large data sets, which will be useful to future time-domain surveys, such as that planned with the Large Synoptic Survey Telescope.

  13. Single event upset suspectibility testing of the Xilinx Virtex II FPGA

    NASA Technical Reports Server (NTRS)

    Carmichael, C.; Swift, C.; Yui, G.

    2002-01-01

    Heavy ion testing of the Xilinx Virtex II was conducted on the configuration, block RAM and user flip flop cells to determine their static single-event upset susceptibility using LETs of 1.2 to 60 MeVcm^2/mg. A software program specifically designed to count errors in the FPGA was used to reveal L1/e, values (the LET at which the cross section is l/e times the saturation cross-section) and single-event functional-interrupt failures.

  14. High-pressure hydrogen testing of single crystal superalloys for advanced rocket engine turbopump turbine blades

    NASA Technical Reports Server (NTRS)

    Alter, W. S.; Parr, R. A.; Johnston, M. H.; Strizak, J. P.

    1984-01-01

    A screening program to determine the effects of high pressure hydrogen on selected candidate materials for advanced single crystal turbine blade applications is examined. The alloys chosen for the investigation are CM SX-2, CM SX-4C, Rene N-4, and PWA1480. Testing is carried out in hydrogen and helium at 34 MPa and room temperature, with both notched and unnotched single crystal specimens. Results show a significant variation in susceptibility to Hydrogen Environment Embrittlement (HEE) among the four alloys and a marked difference in fracture topography between hydrogen and helium environment specimens.

  15. Cost-Effectiveness between Double and Single Fecal Immunochemical Test(s) in a Mass Colorectal Cancer Screening

    PubMed Central

    Cai, Shan-Rong; Zhu, Hong-Hong; Huang, Yan-Qin; Li, Qi-Long; Ma, Xin-Yuan; Zhang, Su-Zhan; Zheng, Shu

    2016-01-01

    This study investigated the cost-effectiveness between double and single Fecal Immunochemical Test(s) (FIT) in a mass CRC screening. A two-stage sequential screening was conducted. FIT was used as a primary screening test and recommended twice by an interval of one week at the first screening stage. We defined the first-time FIT as FIT1 and the second-time FIT as FIT2. If either FIT1 or FIT2 was positive (+), then a colonoscopy was recommended at the second stage. Costs were recorded and analyzed. A total of 24,419 participants completed either FIT1 or FIT2. The detection rate of advanced neoplasm was 19.2% among both FIT1+ and FIT2+, especially high among men with age ≥55 (27.4%). About 15.4% CRC, 18.9% advanced neoplasm, and 29.9% adenoma missed by FIT1 were detected by FIT2 alone. Average cost was $2,935 for double FITs and $2,121 for FIT1 to detect each CRC and $901 for double FITs and $680 for FIT1 to detect each advanced neoplasm. Double FITs are overall more cost-effective, having significantly higher positive and detection rates with an acceptable higher cost, than single FIT. Double FITs should be encouraged for the first screening in a mass CRC screening, especially in economically and medically underserved populations/areas/countries. PMID:27144171

  16. IIST and BETHSY Counterpart Tests on a PWR Total Loss-of-Feedwater Transient with Two Different Bleed-and-Feed Scenarios

    SciTech Connect

    Liu, T.-J

    2002-01-15

    The thermal-hydraulic phenomena and recovery actions of loss-of-feedwater (LOFW) incidents in a pressurized water reactor were investigated experimentally at the Institute of Nuclear Energy Research Integral System Test (IIST) facility. To understand whether the physical phenomena observed in the full-height and full-pressure facility during an LOFW transient can be simulated in the reduced-height and reduced-pressure IIST facility, two counterpart tests based on the same scenarios as those of the BETHSY tests were performed. These two tests performed in BETHSY differ mainly at the initiation of the bleed-and-feed process on the primary side in order to examine the effectiveness of recovery measures on the processes of the pressurizer power-operated relief valves early and late opening. The initial and boundary conditions of the current tests were determined by scaling down the corresponding conditions of the LOFW experiments performed at BETHSY. In view of the inherent differences in design, scaling approach, and facility operation conditions in the systems, the consistency between the counterpart tests is examined by identifying key thermal-hydraulic phenomena and clarifying their differences. The results of the IIST and BETHSY tests showed the common thermal-hydraulic behaviors of key parameters, such as system pressure, void fraction in the hot leg, primary coolant inventory, pressurizer level, and discharged mass evolutions. The chronological events studied in the IIST facility are generally consistent with those studied in BETHSY. The results from the IIST facility may not be exact replications of the BETHSY response; however, the physics involved in bleed-and-feed are well measured and modeled.

  17. Exploring the efficacy of paternity and kinship testing based on single nucleotide polymorphisms.

    PubMed

    Mo, Shao-Kang; Liu, Ya-Cheng; Wang, Sheng-Qi; Bo, Xiao-Chen; Li, Zhen; Chen, Ying; Ni, Ming

    2016-05-01

    Short tandem repeats (STRs) are conventional genetic markers typically used for paternity and kinship testing. As supplementary markers of STRs, single nucleotide polymorphisms (SNPs) have less discrimination power but broader applicability to degraded samples. The rapid improvement of next-generation sequencing (NGS) and multiplex amplification technologies also make it possible now to simultaneously identify dozens or even hundreds of SNP loci in a single pool. However, few studies have been endeavored to kinship testing based on SNP loci. In this study, we genotyped 90 autosomal human identity SNP loci with NGS, and investigated their testing efficacies based on the likelihood ratio model in eight pedigree scenarios involving paternity, half/full-sibling, uncle/nephew, and first-cousin relationships. We found that these SNPs might be sufficient to discriminate paternity and full-sibling, but impractical for more distant relatives such as uncle and cousin. Furthermore, we conducted an in silico study to obtain the theoretical tendency of how testing efficacy varied with increasing number of SNP loci. For each testing battery in a given pedigree scenario, we obtained distributions of logarithmic likelihood ratio for both simulated relatives and unrelated controls. The proportion of the overlapping area between the two distributions was defined as a false testing level (FTL) to evaluate the testing efficacy. We estimated that 85, 127, 491, and 1,858 putative SNP loci were required to discriminate paternity, full-sibling, half-sibling/uncle-nephew, and first-cousin (FTL, 0.1%), respectively. To test a half-sibling or nephew, an additional uncle relative could be included to decrease the required number of putative SNP loci to ∼320 (FTL, 0.1%). As a systematic computation of paternity and kinship testing based only on SNPs, our results could be informative for further studies and applications on paternity and kinship testing using SNP loci. PMID:26952733

  18. Fluid Structure Interaction in a Cold Flow Test and Transient CFD Analysis of Out-of-Round Nozzles

    NASA Technical Reports Server (NTRS)

    Ruf, Joseph; Brown, Andrew; McDaniels, David; Wang, Ten-See

    2010-01-01

    This viewgraph presentation describes two nozzle fluid flow interactions. They include: 1) Cold flow nozzle tests with fluid-structure interaction at nozzle separated flow; and 2) CFD analysis for nozzle flow and side loads of nozzle extensions with various out-of-round cases.

  19. TRAC analysis of the effect of increased ECC subcooling on the reflood transient in the Slab Core Test Facility. [PWR

    SciTech Connect

    Smith, S.T.

    1982-01-01

    A blind posttest calculation of Slab Core Test Facility (SCTF) Run 510, the high-subcooling test, was completed with TRAC-PD2/MOD1 using initial conditions provided by the Japan Atomic Energy Research Institute (JAERI), but without knowledge of the actual test results. There is good comparison between the calculation and the data for rod temperatures, turnaround times, core differential pressures, and mass inventories, and reasonable comparison for absolute pressures, upper plenum pool formation, and fluid temperatures and mass accumulation in the steam-water separator. Comparison of this calculation with the calculation of the base case test (Run 507) shows that the qualitative behavior during reflood is calculated correctly for both cases. In addition, from this comparison the following conclusions can be drawn: for the high-subcooling case, the peak rod temperture was lower, calculated quench times were earlier, there was more entrainment and liquid carryover from the core to the upper plenum, and the liquid mass accumulation in both the core and the upper plenum was greater.

  20. Testing a new automated single ring infiltrometer for Beerkan infiltration experiments

    NASA Astrophysics Data System (ADS)

    Di Prima, Simone; Lassabatère, Laurent; Angulo-Jaramillo, Rafael; Bagarello, Vincenzo; Iovino, Massimo

    2015-04-01

    The Beerkan method along with BEST algorithms is an alternative technique to conventional laboratory or field measurements for rapid and low-cost estimation of soil hydraulic properties. The Beerkan method is simple to conduct but requires an operator to pour known volumes of water through the ring and can be time-consuming. To alleviate this need, a new cheap infiltrometer equipped with a data acquisition system, allowing automation of Beerkan infiltration experiments, was recently designed and is presented in a companion paper. Yet, it has never been tested against a wide range of experimental conditions (soils, initial water saturation, etc.). In this paper, we tested the automated infiltrometer with the aim to validate its applicability to the Beerkan infiltration experiment under several experimental circumstances. In addition, we assessed the accuracy of BEST methods on the data obtained with the infiltrometer for the estimation of saturated soil hydraulic conductivity and sorptivity. For this purpose, we used both analytically generated and real experimental data. The analytically generated data simulate infiltration experiments carried out with the infiltrometer on five contrasting soils from UNSODA database and different initial water contents. The total volume of water to be infiltrated and the volume increments are fixed by the infiltrometer characteristics. Then, inverse analysis of the analytically generated data was performed using the three available BEST algorithms to derive saturated soil hydraulic conductivity and sorptivity that were compared to the reference values. The results of the analytical assessment showed that the infiltrometer along with BEST methods could lead to accurate estimates in most cases thus validating the design of the studied infiltrometer and its combination with BEST algorithms. Some soils (mostly loam) and some hydric conditions (high initial water contents) may lead to misestimate soil properties or failure of BEST algorithms according to numerical results. In these cases, the failures are due to the fact that steady state is not properly reached or the transient state is not properly described (not enough points in the transient state). Finally, the infiltrometer was tested in different soil types. All experiments were carried in an infiltration basin located in the pumping well filed of Crépieux-Charmy, which provides drinking water for the Lyon metropolitan area. Water infiltration experiments were conducted on the subsoil, the layer of sand embedded at surface, either clean or clogged. Experiments and analysis with BEST algorithms proved efficient to pinpoint the decrease in hydraulic conductivity due to clogging. The experiments showed that the automatic data collection increases measurement speeds and allows for more efficient data handling and analysis.

  1. Evidence of Multi-Process Matrix Diffusion in a Single Fracturefrom a Field Tracer Test

    SciTech Connect

    Zhou, Quanlin; Liu, Hui-Hai; Bodvarsson, Gudmundur; Molz, Fred J.

    2005-06-11

    Compared to values inferred from laboratory tests on matrix cores, many field tracer tests in fractured rock have shown enhanced matrix diffusion coefficient values (obtained using a single-process matrix-diffusion model with a homogeneous matrix diffusion coefficient). To investigate this phenomenon, a conceptual model of multi-process matrix diffusion in a single-fracture system was developed. In this model, three matrix diffusion processes of different diffusion rates were assumed to coexist: (1) diffusion into stagnant water and infilling materials within fractures, (2) diffusion into a degraded matrix zone, and (3) further diffusion into an intact matrix zone. The validity of the conceptual model was then demonstrated by analyzing a unique tracer test conducted using a long-time constant-concentration injection. The tracer-test analysis was conducted using a numerical model capable of tracking the multiple matrix-diffusion processes. The analysis showed that in the degraded zone, a diffusion process with an enhanced diffusion rate controlled the steep rising limb and decay-like falling limb in the observed breakthrough curve, whereas in the intact matrix zone, a process involving a lower diffusion rate affected the long-term middle platform of slowly increasing tracer concentration. The different matrix-diffusion-coefficient values revealed from the field tracer test are consistent with the variability of matrix diffusion coefficient measured for rock cores with different degrees of fracture coating at the same site. By comparing to the matrix diffusion coefficient calibrated using single-process matrix diffusion, we demonstrated that this multi-process matrix diffusion may contribute to the enhanced matrix-diffusion-coefficient values for single-fracture systems at the field scale.

  2. Pollution emissions from single swirl-can combustor modules at parametric test conditions

    NASA Technical Reports Server (NTRS)

    Mularz, E. J.; Wear, J. D.; Verbulecz, P. W.

    1975-01-01

    Exhaust pollutant emissions were measured from single swirl-can combustor modules operating over a pressure range of 69 to 276 N/sq cm (100 to 400 psia), over a fuel-air ratio range of 0.01 to 0.04, at an inlet air temperature of 733 K (860 F), and at a constant reference velocity of 23.2 m/sec). Many swirl-can module designs were evaluated; the 11 most promising designs exhibited oxides of nitrogen emission levels lower than that from conventional gas-turbine combustors. Although these single module test results are not necessarily indicative of the performance characteristics of a large array of modules, the results are very promixing and offer a number of module designs that should be tested in a full combustor.

  3. High-Gradient Tests of the Single-Cell SC Cavity with a Feedback Waveguide

    SciTech Connect

    Yakovlev, V.; Solyak, N.; Wu, G.; Ge, M.; Gonin, I.; Khabiboulline, T.; Ozelis, J.; Rowe, A.; Avrakhov, P.; Kanareykin, A.; Rathke, J.

    2010-11-04

    Use of a superconducting (SC) traveling-wave accelerating (STWA) structure with a small phase advance per cell, rather than a standing-wave structure, may provide a significant increase in the accelerating gradient in the ILC linac [1]. For the same surface electric and magnetic fields, the STWA achieves an accelerating gradient 1.2 larger than TESLA-like standing-wave cavities. In addition, the STWA allows longer acceleration cavities, reducing the number of gaps between them. However, the STWA structure requires a SC feedback waveguide to return the few hundreds of MW of circulating RF power from the structure output to the structure input. A test single-cell cavity with feedback was designed and manufactured to demonstrate the possibility of proper processing to achieve a high accelerating gradient. The first results of high-gradient tests of a prototype 1.3 GHz single-cell cavity with feedback waveguide will be presented.

  4. Interpretation of transmissivity estimates from single-well pumping aquifer tests

    USGS Publications Warehouse

    Halford, K.J.; Weight, W.D.; Schreiber, R.P.

    2006-01-01

    Interpretation of single-well tests with the Cooper-Jacob method remains more reasonable than most alternatives. Drawdowns from 628 simulated single-well tests where transmissivity was specified were interpreted with the Cooper-Jacob straight-line method to estimate transmissivity. Error and bias as a function of vertical anisotropy, partial penetration, specific yield, and interpretive technique were investigated for transmissivities that ranged from 10 to 10,000 m2/d. Cooper-Jacob transmissivity estimates in confined aquifers were affected minimally by partial penetration, vertical anisotropy, or analyst. Cooper-Jacob transmissivity estimates of simulated unconfined aquifers averaged twice the known values. Transmissivity estimates of unconfined aquifers were not improved by interpreting results with an unconfined aquifer solution. Judicious interpretation of late-time data consistently improved estimates where transmissivity exceeded 250 m2/d in unconfined aquifers. ?? 2006 National Ground Water Association.

  5. Single well surfactant test to evaluate surfactant floods using multi tracer method

    DOEpatents

    Sheely, Clyde Q.

    1979-01-01

    Data useful for evaluating the effectiveness of or designing an enhanced recovery process said process involving mobilizing and moving hydrocarbons through a hydrocarbon bearing subterranean formation from an injection well to a production well by injecting a mobilizing fluid into the injection well, comprising (a) determining hydrocarbon saturation in a volume in the formation near a well bore penetrating formation, (b) injecting sufficient mobilizing fluid to mobilize and move hydrocarbons from a volume in the formation near the well bore, and (c) determining the hydrocarbon saturation in a volume including at least a part of the volume of (b) by an improved single well surfactant method comprising injecting 2 or more slugs of water containing the primary tracer separated by water slugs containing no primary tracer. Alternatively, the plurality of ester tracers can be injected in a single slug said tracers penetrating varying distances into the formation wherein the esters have different partition coefficients and essentially equal reaction times. The single well tracer method employed is disclosed in U.S. Pat. No. 3,623,842. This method designated the single well surfactant test (SWST) is useful for evaluating the effect of surfactant floods, polymer floods, carbon dioxide floods, micellar floods, caustic floods and the like in subterranean formations in much less time and at much reduced cost compared to conventional multiwell pilot tests.

  6. Single-well "push-pull" partitioning tracer test for NAPL detection in the subsurface.

    PubMed

    Istok, Jonathan D; Field, Jennifer A; Schroth, Martin H; Davis, Brian M; Dwarakanath, Varadarajan

    2002-06-15

    Previous environmental applications of partitioning tracer tests to detect and quantify nonaqueous phase liquid (NAPL) contamination in the subsurface have been limited to well-to-well tests. However, theory and numerical modeling suggests that single-well injection-extraction ("push-pull") partitioning tracer tests can also potentially detect and quantify NAPL contamination. In this type of test, retardation factors for injected partitioning tracers are estimated from the increase in apparent dispersion observed in extraction-phase breakthrough curves in the presence of NAPL. A series of laboratory push-pull tests was conducted in physical aquifer models (PAMs) packed with natural aquifer sediment prepared with and without the presence of trichloroethene (TCE) NAPL. Field tests were conducted in an aquifer contaminated with petroleum hydrocarbon NAPL. Injected test solutions contained a suite of partitioning and conservative (nonpartitioning) alcohol tracers. Laboratory push-pull partitioning tracer tests were able to detect and quantify sorption of partitioning tracers to aquifer sediment (in the absence of NAPL) and to detect NAPL when it was present. NAPL saturations computed from estimated retardation factors bracketed those computed from known volumes of emplaced NAPL in the sediment pack. However, numerical modeling with assumed homogeneous NAPL distribution and linear equilibrium partitioning of tracers between aqueous and NAPL phases was unable to reproduce all features of observed breakthrough curves. Excavation of the sediment pack after all tests indicated that a portion of the emplaced NAPL had sunk to the bottom of the PAM invalidating the modeling assumption of homogeneous NAPL distribution. Moreover, the apparent dispersion in extraction-phase breakthrough curves decreased when the injection-extraction pumping rate was decreased, suggesting that mass transfer limitations existed during laboratory tests. Field push-pull partitioning tracer tests were able to detect NAPL in a portion of the aquifer known to contain NAPL; computed NAPL saturations were comparble to those obtained from sediment coring and the results of a partitioning interwell tracer test conducted in the same location. This study clearly demonstrates that the single-well partitioning tracer test can detect NAPL under both laboratory and field conditions. However, additional research is needed to verify the ability of the test to quantify NAPL saturations. PMID:12099468

  7. Finite Element Modeling of Transient Head Field Associated with Partially Penetrating, Slug Tests in a Heterogeneous Aquifer with Low Permeability, Stratigraphic Zones and Faults

    NASA Astrophysics Data System (ADS)

    Cheng, J.; Johnson, B.; Everett, M.

    2003-12-01

    Preliminary field work shows slug interference tests using an array of multilevel active and monitoring wells have potential of permitting enhanced aquifer characterization. Analysis of these test data, however, ultimately will rely on numerical geophysical inverse models. In order to gain insight as well as to provide synthetic data sets, we use a 3-D finite element analysis (code:FEHM-LANL) to explore the effect of idealized, low permeability, stratigraphical and structural (faults) heterogeneities on the transient head field associated with a slug test in a packer-isolated interval of an open borehole. The borehole and packers are modeled explicitly; wellbore storage is selected to match values of field tests. The homogeneous model exhibits excellent agreement with that of the semi-analytical model of Liu and Butler (1995). Models are axisymmetric with a centrally located slugged interval within a homogenous, isotropic, confined aquifer with embedded, horizontal or vertical zones of lower permeability that represent low permeability strata or faults, respectively. Either one or two horizontal layers are located opposite the borehole packers, which is a common situation at the field site; layer thickness (0.15-0.75 m), permeability contrast (up to 4 orders of magnitude contrast) and lateral continuity of layers are varied between models. The effect of a "hole" in a layer also is assessed. Fault models explore effects of thickness (0.05-0.75 m) and permeability contrast as well as additional effects associated with the offset of low permeability strata. Results of models are represented most clearly by contour maps of time of arrival and normalized amplitude of peak head perturbation, but transient head histories at selected locations provide additional insight. Synthesis of the models is on-going but a few points can be made at present. Spatial patterns are distinctive and allow easy discrimination between stratigraphic and structural impedance features. Time delays and amplitude reduction increase nonlinearly with increasing permeability contrast. The capacity to discriminate the effect of layer thickness decreases as permeability contrast increases.

  8. Novel Application of Single-Well Tracer Tests to Evaluate Hydraulic Stimulation Effectiveness

    SciTech Connect

    G. M. Shook; Gopi Nalla

    2005-09-01

    This paper presents a graphical method by which one can identify the number of fractures and their permeability distribution in the near-well region from single-well tracer tests. The method is an extension of tracer analysis methods developed previously to estimate flow geometry and relies on caluclating the relative fluid velocity from F-__ plots. A number of numerical examples show that high flow zones (fractures) are readily identified from the derivatives of an F-___ curve. The method can be used in evaluating well stimulation efforts by conducting a tracer test before and after the stimulation and comparing the velocity distributions.

  9. Allison engine testing CMSX-4{reg_sign} single crystal turbine blades and vanes

    SciTech Connect

    Burkholder, P.S.; Thomas, M.C.; Frasier, D.J.; Whetstone, J.R.; Harris, K.; Erickson, G.L.; Sikkenga, S.L.; Eridon, J.M.

    1995-05-01

    A team approach utilizing simultaneous engineering has been used to develop CMSX-4 turbine airfoil components. CMSX-4 is a nickel-base single crystal superalloy containing 3% (wt) rhenium and a high 71% volume fraction of coherent {gamma}{prime} precipitate strengthening phase. The high level of balanced properties determined by extensive laboratory evaluation has been confirmed during engine testing the Allison AE 2100 and AE 301X engines, with the post-test condition of the components, including advanced Castcool{trademark} vane segments, being excellent. Also uncooled vane segments in CMSX-4 have exceeded engineering expectations.

  10. High gradient test of the HINS SSR1 single spoke resonator

    SciTech Connect

    Gonin, I.; Khabibouline, T.; Lanfranco, G.; Mukherjee, A.; Ozelis, JH.; Ristori, L.; Sergatskov, A.; Wagner, R.; Webber, R.; /Fermilab

    2008-09-01

    Eighteen {beta} = 0.21 superconducting single spoke resonators comprise the first state in the cold section of the 8-GeV H{sup -} Linac for Fermilab's proposed Project X. After Buffered Chemical Polishing and High Pressure Rinse, one resonator has undergone high gradient RF testing at 2.0-4.5 K in the Vertical Test Stand at Fermilab. They present measurements of the surface resistance as a function of temperature and the quality factor as a function of accelerating field. The resonator reached an accelerating field of 18.0 MV/m.

  11. Testing of plain and fibrous concrete single cavity prestressed concrete reactor vessel models

    SciTech Connect

    Oland, C.B.

    1985-01-01

    Two single-cavity prestressed concrete reactor vessel (PCRV) models were fabricated and tested to failure to demonstrate the structural response and ultimate pressure capacity of models cast from high-strength concretes. Concretes with design compressive strengths in excess of 70 MPa (10,000 psi) were developed for this investigation. One model was cast from plain concrete and failed in shear at the head region. The second model was cast from fiber reinforced concrete and failed by rupturing the circumferential prestressing at the sidewall of the structure. The tests also demonstrated the capabilities of the liner system to maintain a leak-tight pressure boundary. 3 refs., 4 figs.

  12. Proton Single Event Effects (SEE) Testing of the Myrinet Crossbar Switch and Network Interface Card

    NASA Technical Reports Server (NTRS)

    Howard, James W., Jr.; LaBel, Kenneth A.; Carts, Martin A.; Stattel, Ronald; Irwin, Timothy L.; Day, John H. (Technical Monitor)

    2002-01-01

    As part of the Remote Exploration and Experimentation Project (REE), work was performed to do a proton SEE (Single Event Effect) evaluation of the Myricom network protocol system (Myrinet). This testing included the evaluation of the Myrinet crossbar switch and the Network Interface Card (NIC). To this end, two crossbar switch devices and five components in the NIC were exposed to the proton beam at the University of California at Davis Crocker Nuclear Laboratory (CNL).

  13. Study of the comminution characteristics of coal by single particle breakage test device

    SciTech Connect

    Sahoo, R.

    2005-09-01

    Single-particle breakage tests of South Blackwater and Ensham coal from the Bowen Basin area in Queensland were conducted by a computer-monitored twin-pendulum device to measure the energy utilization pattern of the breakage particles. Three particle sizes (-16.0+13.2mm, -13.2+11.2mm, -11.2+9.5mm) of each coal were tested by a pendulum device at five input energy levels to measure the specific comminution energy. When particles were tested at constant input energy, the variation of comminution energy between the same size broken particles of Ensham coal was minimal, because Ensham coal is a softer and higher friability coal, which absorbs more input energy than harder coal during breakage tests. For different particle sizes, the specific comminution energy increases linearly with the input energy and the fineness of the breakage products increases with the specific comminution energy. The size distribution graphs are curved but approach linearity in the finer region. At a constant input energy, the twin pendulum breakage product results show that the fineness of the products increases with decrease in particle size and South Blackwater coal produced finer products than the Ensham coal. The t-curves are the family of size distribution curves, which can describe the product size distribution of the breakage particles during single-particle breakage tests.

  14. Single cell antimicrobial susceptibility testing by confined microchannels and electrokinetic loading

    PubMed Central

    Lu, Yi; Gao, Jian; Zhang, Donna D.; Gau, Vincent; Liao, Joseph C.; Wong, Pak Kin

    2014-01-01

    Multidrug-resistant pathogens are an emerging global health problem. In addition to the need of developing new antibiotics in the pipeline, the ability to rapidly determine the antibiotic resistance profiles of bacteria represents one of the most crucial steps toward the management of infectious diseases and the prevention of multidrug-resistant pathogens. Here, we report a single cell antimicrobial susceptibility testing (AST) approach for rapid determination of the antibiotic resistance of bacterial pathogens. By confining individual bacteria in gas permeable microchannels with dimensions comparable to a single bacterium, the antibiotic resistance of the bacteria can be monitored in real-time at the single cell level. To facilitate the dynamic loading of the bacteria into the confined microchannels for observation, AC electrokinetics is demonstrated for capturing bacteria to defined locations in high-conductivity AST buffer. The electrokinetic technique achieves a loading efficiency of about 75% with a negligible effect on the bacterial growth rate. To optimize the protocol for single cell AST, the bacterial growth rate of individual bacteria under different antibiotic conditions has been determined systematically. The applicability of single cell AST is demonstrated by the rapid determination of the antimicrobial resistant profiles of uropathogenic clinical isolates in Mueller-Hinton media and in urine. The antibiotic resistance profiles of bacteria can be determined in less than one hour compared to days in standard culture-based AST techniques. PMID:23445209

  15. Single-step gastric aspirate shake test: bedside predictor of neonatal pulmonary morbidity.

    PubMed Central

    Tanswell, A K; Sherwin, E; Smith, B T

    1977-01-01

    A simplified, single-step shake test has been performed on gastric aspirate samples from 85 preterm infants and a control group of 214 term infants. Respiratory symptoms were seen in 25 of 30 preterm infants with a negative or intermediate test, but in only 2 of 55 infants with a positive test (P less than 0-001). No infant with a positive test developed respiratory distress syndrome (RDS) while RDS developed in 66% of those preterm infants with a negative test. False-negative results were not seen in the preterm group. The gastric aspirate shake test had better sensitivity and selectivity in prediction of clinical outcome than did the amniotic fluid lecithin/sphingomyelin ratio in 37 preterm infants in whom both results were available. Serial shake tests were performed on samples from a number of infants with RDS and the results were seen to change in parallel with clinical recovery. This and other observations suggest that the result of the gastric aspirate shake test depends more upon direct swallowing of fetal lung liquid than on swallowing of amniotic fluid. PMID:577669

  16. Fabrication and Testing of Full-Length Single-Cell Externally Fueled Converters for Thermionic Reactors

    SciTech Connect

    Schock, Alfred

    1994-06-01

    The preceding paper described designs and analyses of thermionic reactors employing full-core-length single-cell converters with their heated emitters located on the outside of their internally cooled collectors, and it presented results of detailed parametric analyses which illustrate the benefits of this unconventional design. The present paper describes the fabrication and testing of full-length prototypical converters, both unfueled and fueled, and presents parametric results of electrically heated tests. The unfueled converter tests demonstrated the practicality of operating such long converters without shorting across a 0.3-mm interelectrode gap. They produced a measured peak output of 751 watts(e) from a single diode and a peak efficiency of 15.4%. The fueled converter tests measured the parametric performance of prototypic UO(subscript 2)-fueled converters designed for subsequent in-pile testing. They employed revolver-shaped tungsten elements with a central emitter hole surrounded by six fuel chambers. The full-length converters were heated by a water-cooled RF-induction coil inside an ion-pumped vacuum chamber. This required development of high-vacuum coaxial RF feedthroughs. In-pile test rules required multiple containment of the UO (subscript 2)-fuel, which complicated the fabrication of the test article and required successful development of techniques for welding tungsten and other refractory components. The test measured a peak power output of 530 watts(e) or 7.1 watts/cm (superscript 2) at an efficiency of 11.5%. There are three copies in the file. Cross-Reference a copy FSC-ESD-217-94-529 in the ESD files with a CID #8574.

  17. Temperature in a J47-25 Turbojet-engine Combustor and Turbine Sections During Steady-state and Transient Operation in a Sea-level Test Stand

    NASA Technical Reports Server (NTRS)

    Morse, C R; Johnston, J R

    1955-01-01

    In order to determine the conditions of engine operation causing the most severe thermal stresses in the hot parts of a turbojet engine, a J47-25 engine was instrumented with thermocouples and operated to obtain engine material temperatures under steady-state and transient conditions. Temperatures measured during rated take-off conditions of nozzle guide vanes downstream of a single combustor differed on the order of 400 degrees F depending on the relation of the blades position to the highest temperature zone of the burner. Under the same operation conditions, measured midspan temperatures in a nozzle guide vane in the highest temperature zone of a combustor wake ranged from approximately 1670 degrees F at leading and trailing edges to 1340 degrees F at midchord on the convex side of the blade. The maximum measured nozzle-guide-vane temperature of 1920degrees at the trailing edge occurred during a rapid acceleration from idle to rated take-off speed following which the tail-pipe gas temperature exceeded maximum allowable temperature by 125 degrees F.

  18. Classifying performance impairment in response to sleep loss using pattern recognition algorithms on single session testing

    PubMed Central

    St. Hilaire, Melissa A.; Sullivan, Jason P.; Anderson, Clare; Cohen, Daniel A.; Barger, Laura K.; Lockley, Steven W.; Klerman, Elizabeth B.

    2012-01-01

    There is currently no “gold standard” marker of cognitive performance impairment resulting from sleep loss. We utilized pattern recognition algorithms to determine which features of data collected under controlled laboratory conditions could most reliably identify cognitive performance impairment in response to sleep loss using data from only one testing session, such as would occur in the “real world” or field conditions. A training set for testing the pattern recognition algorithms was developed using objective Psychomotor Vigilance Task (PVT) and subjective Karolinska Sleepiness Scale (KSS) data collected from laboratory studies during which subjects were sleep deprived for 26 – 52 hours. The algorithm was then tested in data from both laboratory and field experiments. The pattern recognition algorithm was able to identify performance impairment with a single testing session in individuals studied under laboratory conditions using PVT, KSS, length of time awake and time of day information with sensitivity and specificity as high as 82%. When this algorithm was tested on data collected under real-world conditions from individuals whose data were not in the training set, accuracy of predictions for individuals categorized with low performance impairment were as high as 98%. Predictions for medium and severe performance impairment were less accurate. We conclude that pattern recognition algorithms may be a promising method for identifying performance impairment in individuals using only current information about the individual’s behavior. Single testing features (e.g., number of PVT lapses) with high correlation with performance impairment in the laboratory setting may not be the best indicators of performance impairment under real-world conditions. Pattern recognition algorithms should be further tested for their ability to be used in conjunction with other assessments of sleepiness in real-world conditions to quantify performance impairment in response to sleep loss. PMID:22959616

  19. Platelet function testing in transient ischaemic attack and ischaemic stroke: A comprehensive systematic review of the literature.

    PubMed

    Lim, Soon Tjin; Coughlan, Catherine A; Murphy, Stephen J X; Fernandez-Cadenas, Israel; Montaner, Joan; Thijs, Vincent; Marquardt, Lars; McCabe, Dominick J H

    2015-01-01

    The majority of patients with ischaemic cerebrovascular disease (CVD) are not protected from further vascular events with antiplatelet therapy. Measurement of inhibition of platelet function ex vivo on antiplatelet therapy, using laboratory tests that correlate with the clinical effectiveness of these agents, would potentially enable physicians to tailor antiplatelet therapy to suit individuals. A systematic review of the literature was performed to collate all available data on ex vivo platelet function/reactivity in CVD patients, especially those treated with aspirin, dipyridamole or clopidogrel. Particular emphasis was paid to information from commonly available whole blood platelet function analysers (PFA-100®, VerifyNow® and Multiplate®). Data on pharmacogenetic mechanisms potentially influencing high on-treatment platelet reactivity (HTPR) on antiplatelet therapy in CVD were reviewed. Two-hundred forty-nine potentially relevant articles were identified; 93 manuscripts met criteria for inclusion. The prevalence of ex vivo HTPR in CVD varies between 3-62% with aspirin monotherapy, 8-61% with clopidogrel monotherapy and 56-59% when dipyridamole is added to aspirin in the early, subacute or late phases after TIA/stroke onset. The prevalence of HTPR on aspirin was higher on the PFA-100 than on the VerifyNow in one study (p < 0.001). Furthermore, the prevalence of HTPR on aspirin was lower when one used 'novel longitudinal' rather than 'cross-sectional, case-control' definitions of HTPR on the PFA early after TIA or stroke (p = 0.003; 1 study). Studies assessing the influence of genetic polymorphisms on HTPR in CVD patients are limited, and need validation in large multicentre studies. Available data illustrate that an important proportion of CVD patients have ex vivo HTPR on their prescribed antiplatelet regimen, and that the prevalence varies depending on the definition and assay used. Large, adequately-sized, prospective multicentre collaborative studies are urgently needed to determine whether comprehensive assessment of HTPR at high and low shear stress with a range of user-friendly whole blood platelet function testing platforms, in conjunction with pharmacogenetic data, improves our ability to predict the risk of recurrent vascular events in CVD patients, and thus enhance secondary prevention following TIA or ischaemic stroke. PMID:26042726

  20. A rapid antimicrobial susceptibility test based on single-cell morphological analysis.

    PubMed

    Choi, Jungil; Yoo, Jungheon; Lee, Mincheol; Kim, Eun-Geun; Lee, Ji Soo; Lee, Seungok; Joo, Seik; Song, Sang Hoon; Kim, Eui-Chong; Lee, Jung Chan; Kim, Hee Chan; Jung, Yong-Gyun; Kwon, Sunghoon

    2014-12-17

    A rapid antibiotic susceptibility test (AST) is desperately needed in clinical settings for fast and appropriate antibiotic administration. Traditional ASTs, which rely on cell culture, are not suitable for urgent cases of bacterial infection and antibiotic resistance owing to their relatively long test times. We describe a novel AST called single-cell morphological analysis (SCMA) that can determine antimicrobial susceptibility by automatically analyzing and categorizing morphological changes in single bacterial cells under various antimicrobial conditions. The SCMA was tested with four Clinical and Laboratory Standards Institute standard bacterial strains and 189 clinical samples, including extended-spectrum β-lactamase-positive Escherichia coli and Klebsiella pneumoniae, imipenem-resistant Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus, and vancomycin-resistant Enterococci from hospitals. The results were compared with the gold standard broth microdilution test. The SCMA results were obtained in less than 4 hours, with 91.5% categorical agreement and 6.51% minor, 2.56% major, and 1.49% very major discrepancies. Thus, SCMA provides rapid and accurate antimicrobial susceptibility data that satisfy the recommended performance of the U.S. Food and Drug Administration. PMID:25520395

  1. A neutrality test for detecting selection on DNA methylation using single methylation polymorphism frequency spectrum.

    PubMed

    Wang, Jun; Fan, Chuanzhu

    2015-01-01

    Inheritable epigenetic mutations (epimutations) can contribute to transmittable phenotypic variation. Thus, epimutations can be subject to natural selection and impact the fitness and evolution of organisms. Based on the framework of the modified Tajima's D test for DNA mutations, we developed a neutrality test with the statistic "D(m)" to detect selection forces on DNA methylation mutations using single methylation polymorphisms. With computer simulation and empirical data analysis, we compared the D(m) test with the original and modified Tajima's D tests and demonstrated that the D(m) test is suitable for detecting selection on epimutations and outperforms original/modified Tajima's D tests. Due to the higher resetting rate of epimutations, the interpretation of D(m) on epimutations and Tajima's D test on DNA mutations could be different in inferring natural selection. Analyses using simulated and empirical genome-wide polymorphism data suggested that genes under genetic and epigenetic selections behaved differently. We applied the D(m) test to recently originated Arabidopsis and human genes, and showed that newly evolved genes contain higher level of rare epialleles, suggesting that epimutation may play a role in origination and evolution of genes and genomes. Overall, we demonstrate the utility of the D(m) test to detect whether the loci are under selection regarding DNA methylation. Our analytical metrics and methodology could contribute to our understanding of evolutionary processes of genes and genomes in the field of epigenetics. The Perl script for the "D(m)" test is available at http://fanlab.wayne.edu/ (last accessed December 18, 2014). PMID:25539727

  2. Infrastructure Development of Single Cell Testing Capability at A0 Facility

    SciTech Connect

    Dhanaraj, Nandhini; Padilla, R.; Reid, J.; Khabiboulline, T.; Ge, M.; Mukherjee, A.; Rakhnov, I.; Ginsburg, C.; Wu, G.; Harms, E.; Carter, H.; /Fermilab

    2009-09-01

    The objective of this technical note is to document the details of the infrastructure development process that was realized at the A0 photo injector facility to establish RF cold testing capability for 1.3 GHz superconducting niobium single cell cavities. The activity began the last quarter of CY 2006 and ended the first quarter of CY 2009. The whole process involved addressing various aspects such as design of vertical insert and lifting fixture, modification of existing RF test station and design of new couplers, development of a Temperature Mapping (T-Map) system, radiation considerations for the test location (north cave), update of existing High Pressure Rinse (HPR) system, preparation of necessary safety documents and eventually obtaining an Operational Readiness Clearance (ORC). Figure 1 illustrates the various components of the development process. In the past, the north cave test station at A0 has supported the cold testing 3.9 GHz nine cell and single cell cavities, thus some of the components were available for use and some needed modification. The test dewar had the capacity to accommodate 1.3 GHz single cells although a new vertical insert that could handle both cavity types (1.3 and 3.9 GHz) had to be designed. The existing cryogenic system with an average capacity of {approx} 0.5 g/sec was deemed sufficient. The RF system was updated with broadband components and an additional amplifier with higher power capacity to handle higher gradients usually achieved in 1.3 GHz cavities. The initial testing phase was arbitrated to proceed with fixed power coupling. A new temperature mapping system was developed to provide the diagnostic tool for hot spot studies, quench characterization and field emission studies. The defining feature of this system was the use of diode sensors instead of the traditional carbon resistors as sensing elements. The unidirectional current carrying capacity (forward bias) of the diodes provided for the ease of multiplexing of the system, thus substantially reducing the number of cables required to power the sensors. The high gradient capacity of the 1.3 GHz cavities required a revision of the radiation shielding and interlocks. The cave was updated as per the recommendations of the radiation safety committee. The high pressure rinse system was updated with new adapters to assist the rinsing 1.3 GHz single cell cavities. Finally, a proposal for cold testing 1.3 GHz single cell cavities at A0 north cave was made to the small experiments approval committee, radiation safety committee and the Tevatron cryogenic safety sub-committee for an operational readiness clearance and the same was approved. The project was classified under research and development of single cell cavities (project 18) and was allocated a budget of $200,000 in FY 2007.

  3. Impact of typical steady-state conditions and transient conditions on flow ripple and its test accuracy for axial piston pump

    NASA Astrophysics Data System (ADS)

    Xu, Bing; Hu, Min; Zhang, Junhui

    2015-09-01

    The current research about the flow ripple of axial piston pump mainly focuses on the effect of the structure of parts on the flow ripple. Therein, the structure of parts are usually designed and optimized at rated working conditions. However, the pump usually has to work in large-scale and time-variant working conditions. Therefore, the flow ripple characteristics of pump and analysis for its test accuracy with respect to variant steady-state conditions and transient conditions in a wide range of operating parameters are focused in this paper. First, a simulation model has been constructed, which takes the kinematics of oil film within friction pairs into account for higher accuracy. Afterwards, a test bed which adopts Secondary Source Method is built to verify the model. The simulation and tests results show that the angular position of the piston, corresponding to the position where the peak flow ripple is produced, varies with the different pressure. The pulsating amplitude and pulsation rate of flow ripple increase with the rise of pressure and the variation rate of pressure. For the pump working at a constant speed, the flow pulsation rate decreases dramatically with the increasing speed when the speed is less than 27.78% of the maximum speed, subsequently presents a small decrease tendency with the speed further increasing. With the rise of the variation rate of speed, the pulsating amplitude and pulsation rate of flow ripple increase. As the swash plate angle augments, the pulsating amplitude of flow ripple increases, nevertheless the flow pulsation rate decreases. In contrast with the effect of the variation of pressure, the test accuracy of flow ripple is more sensitive to the variation of speed. It makes the test accuracy above 96.20% available for the pulsating amplitude of pressure deviating within a range of ±6% from the mean pressure. However, with a variation of speed deviating within a range of ±2% from the mean speed, the attainable test accuracy of flow ripple is above 93.07%. The model constructed in this research proposes a method to determine the flow ripple characteristics of pump and its attainable test accuracy under the large-scale and time-variant working conditions. Meanwhile, a discussion about the variation of flow ripple and its obtainable test accuracy with the conditions of the pump working in wide operating ranges is given as well.

  4. Are single-well "push-pull" tests suitable tracer methods for aquifer characterization?

    NASA Astrophysics Data System (ADS)

    Hebig, Klaus; Zeilfelder, Sarah; Ito, Narimitsu; Machida, Isao; Scheytt, Traugott; Marui, Atsunao

    2013-04-01

    Recently, investigations were conducted for geological and hydrogeological characterisation of the sedimentary coastal basin of Horonobe (Hokkaido, Japan). Coastal areas are typical geological settings in Japan, which are less tectonically active than the mountain ranges. In Asia, and especially in Japan, these areas are often densely populated. Therefore, it is important to investigate the behaviour of solutes in such unconsolidated aquifers. In such settings sometimes only single boreholes or groundwater monitoring wells are available for aquifer testing for various reasons, e.g. depths of more than 100 m below ground level and slow groundwater velocities due to density driven flow. A standard tracer test with several involved groundwater monitoring wells is generally very difficult or even not possible at these depths. One of the most important questions in our project was how we can obtain information about chemical and hydraulic properties in such aquifers. Is it possible to characterize solute transport behaviour parameters with only one available groundwater monitoring well or borehole? A so-called "push-pull" test may be one suitable method for aquifer testing with only one available access point. In a push-pull test a known amount of several solutes including a conservative tracer is injected into the aquifer ("push") and afterwards extracted ("pull"). The measured breakthrough curve during the pumping back phase can then be analysed. This method has already been used previously with various aims, also in the recent project (e.g. Hebig et al. 2011, Zeilfelder et al. 2012). However, different test setups produced different tracer breakthrough curves. As no systematic evaluation of this aquifer tracer test method was done so far, nothing is known about its repeatability. Does the injection and extraction rate influence the shape of the breakthrough curve? Which role plays the often applied "chaser", which is used to push the test solution out from the borehole and gravel pack? How does density difference between the original groundwater and the test solution influence the tracer breakthrough curves? To solve these questions, seven push-pull tests were performed under controlled boundary conditions in the same well DD-2 (100 m depth). Only single parameters, as e.g. flow rate or salinization of the test solution, were varied during the experiments. By conducting these different test setups, conclusions could be drawn about the application of the push-pull method under different settings. References: Hebig, K.H., Ito, N., Scheytt, T.J. & Marui, A. (2011). Hydraulic and hydrochemical characterization of deep coastal sedimentary basins by single-well Push-Pull tests. GSA Annual Meeting, 9-12 October 2011, Minneapolis, USA. Zeilfelder, S., Ito, N., Marui, A., Hebig, K. & Scheytt, T. (2012). Push-Pull-Test und Tracer-Test in ei-nem tiefen Grundwasserleiter in Kameoka, Japan. Kurzfassung in: Liedl, R., Burghardt, D., Simon, E., Reimann, T. & Kaufmann-Knoke (Hg.). Grundwasserschutz und Grundwassernutzung. Tagung der Fachsektion Hydrogeologie in der DGG (FH-DGG). 16. - 20. Mai 2012, Dresden. Kurfassungen der Vorträge und Poster. Schriftenreihe der DGG, Heft 78, S. 192.

  5. Testing The Performance Of A Single-Phase Autotransformer On MATLAB/Simulink

    NASA Astrophysics Data System (ADS)

    Panu, Mihai Gheorghe; Viorel, Alina Cristina

    2015-07-01

    This paper presents a virtual laboratory for testing a single-phase autotransformer using MATLAB Simulink environment. The model is implemented according to a practical laboratory used at electric machines' discipline for the undergraduate level in electrical engineering. The model presented herein is a copy of a practical experiment for an autotransformer made in the test laboratory. The rating of the autotransformer is taken to be 2 kVA, 230/0230 V, and it was set at a transformer ratio of 1.5. The used model is a linear one and run for a pure resistive load test. In the same time, it was aimed the simulation accuracy as it was used a linear model, neglecting the magnetic saturation effect.

  6. The development and testing of a heat pump for heating a single room

    NASA Astrophysics Data System (ADS)

    Freund, P.; Cattell, R. K.

    1980-12-01

    The development and testing of a heat pump designed to provide heat only to a single room of a dwelling are discussed. The through-the-wall unit is an air-to-air heat pump based on standard refrigeration components, with various noise-reduction, control and heat exchanger components added. Measurements of heat output, the extraction of heat from a cold chamber, electric power consumption, air flow rates and temperatures at various points were performed in a test facility built to evaluate air-source heat pumps. Test results indicate that the expected rate of heat output is achieved at high temperatures, however heat output is less than expected at lower temperatures due to heat loss within the unit. The ratio of heat output to total electrical consumption indicates optimized performance in the region of 5 C ambient temperature, although at levels less than had been expected. Means of reducing heat losses and improving the efficiency of the unit are suggested.

  7. Single-dose Intravenous Toxicology Testing of Daebohwalryeok Pharmcopuncture in Sprague-Dawley Rats

    PubMed Central

    Sun, Seung-Ho; Park, Sunju; Jeong, Jong-Jin; Lee, Kwang-Ho; Yu, Jun-Sang; Seo, Hyung-Sik; Kwon, Ki-Rok

    2015-01-01

    Objectives: The aims of the study were to test the single-dose intravenous toxicity of Daebohwalryeok pharmacopuncture (DHRP) in Sprague-Dawley (SD) rats and to estimate the crude lethal dose. Methods: The experiments were conducted at Biotoxtech Co., a Good Laboratory Practice (GLP) laboratory, according to the GLP regulation and were approved by the Institutional Animal Care and Use Committee of Biotoxtech Co. (Approval no: 110156). The rats were divided into three groups: DHRP was injected into the rats in the two test groups at doses of 10 mL/kg and 20 mL/kg, respectively, and normal saline solution was injected into the rats in the control group. Single doses of DHRP were injected intravenously into 6 week old SD rats (5 male and 5 female rats per group). General symptoms were observed and weights were measured during the 14 day observation period after the injection. After the observation period, necropsies were done. Then, histopathological tests were performed. Weight data were analyzed with a one-way analysis of variance (ANOVA) by using statistical analysis system (SAS, version 9.2). Results: No deaths and no statistical significant weight changes were observed for either male or female SD rats in either the control or the test groups during the observation period. In addition, no treatment related general symptoms or necropsy abnormalities were observed. Histopathological results showed no DHRP related effects in the 20 mL/kg DHRP group for either male or female rats. Conclusion: Under the conditions of this study, the results from single-dose intravenous injections of DHRP showed that estimated lethal doses for both male and female rats were above 20 mL/kg. PMID:26120487

  8. Single Rod Heat Transfer Tests to Study the Effects of Crud Deposition

    SciTech Connect

    Wang, G.; Byers, W.A.; Karoutas, Z.E.; Young, M.Y.; Jacko, R.J.; Hochreiter, L.E.

    2006-07-01

    Researchers have performed many studies to try to understand crud formation on the fuel pin clad surfaces, which has been observed in pressurized water reactors (PWR) as a result of sub-cooled nucleate boiling and precipitation reactions. Crud deposits, may cause an unexpected change in core power distribution known as crud induced power shift (CIPS) or axial offset anomaly (AOA) if boron species accumulate in the deposits. If the crud deposit is thick enough, the potential exists for fuel rod surface dryout. The Westinghouse Advanced Loop Tester (WALT) at the George Westinghouse Science and Technology Center (STC) will be utilized to examine the effects of crud formation on fuel pin clad dryout. This paper describes a single heated rod test facility designed and fabricated by Westinghouse to study the effects of crud deposition at PWR reactor operating conditions. This test loop is a single rod facility with or without grid support structures on the heater rod and can be used for forced convection and sub-cooled boiling tests with and without crud deposition. Sub-cooled boiling experiments at PWR reactor operating conditions are currently being performed at this facility. The single electrical heated rod in this test facility is instrumented with four movable thermocouples to measure the inside wall temperatures at four azimuthal locations within the rod. In addition, there are two fixed thermocouples to measure the inlet and outlet temperatures of the water flowing on the outside of the heated rod such that an overall energy balance (i.e. comparing the heat absorbed by the water coolant to the measured rod electrical power) can be performed on the facility. This paper will present forced convection and boiling heat transfer curves for clean rod surfaces. Comparison with forced convection correlations and sub-cooled boiling correlations are also presented in this paper. (authors)

  9. 42 CFR 84.1145 - Silica dust test; non-powered single-use dust respirators; minimum requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Silica dust test; non-powered single-use dust respirators; minimum requirements. 84.1145 Section 84.1145 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF... Efficiency Respirators and Combination Gas Masks § 84.1145 Silica dust test; non-powered single-use...

  10. 42 CFR 84.1145 - Silica dust test; non-powered single-use dust respirators; minimum requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Silica dust test; non-powered single-use dust respirators; minimum requirements. 84.1145 Section 84.1145 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF... Efficiency Respirators and Combination Gas Masks § 84.1145 Silica dust test; non-powered single-use...

  11. 42 CFR 84.1145 - Silica dust test; non-powered single-use dust respirators; minimum requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Silica dust test; non-powered single-use dust respirators; minimum requirements. 84.1145 Section 84.1145 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF... Efficiency Respirators and Combination Gas Masks § 84.1145 Silica dust test; non-powered single-use...

  12. 42 CFR 84.1145 - Silica dust test; non-powered single-use dust respirators; minimum requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Silica dust test; non-powered single-use dust respirators; minimum requirements. 84.1145 Section 84.1145 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF... Efficiency Respirators and Combination Gas Masks § 84.1145 Silica dust test; non-powered single-use...

  13. Design, implementation, and testing of a single axis levitation system for the suspension of a platform.

    PubMed

    Banerjee, Subrata; Prasad, Dinkar; Pal, Jayanta

    2007-04-01

    This paper describes the design and implementation of a single axis DC attraction type suspension system, where a platform (vehicle structure) of around 14 kg mass is made to remain suspended at the desired operating gap under a ferromagnetic guide-way. The prototype has four electromagnetic actuators of attraction type and four inductive gap sensors, all located at the corners of the platform. The four actuators are controlled independently through four identical controllers, and the stable levitation of the platform is achieved through the single input and single output (SISO) control of each air-gap. The emphasis of this work is on the design and development of the switched mode power amplifier cum controller unit for the four actuators. The proposed single switch-based power circuit simplifies the overall hardware, and it can be extended to any number of magnet-coils. A cascade lead compensation control scheme utilizing an inner current loop and outer position loop has been designed and implemented for the stabilization of such a highly unstable and strongly nonlinear system. The prototype has been successfully tested, and stable levitation was demonstrated with the desired operating gap. PMID:17350630

  14. Robust Filtering of Artifacts in Difference Imaging for Rapid Transients Detection

    NASA Astrophysics Data System (ADS)

    Klencki, J.; Wyrzykowski, Ł.; Kostrzewa-Rutkowska, Z.; Udalski, A.

    2016-01-01

    Real-time analysis and classification of observational data collected within synoptic sky surveys is a huge challenge due to constant growth of data volumes. Machine learning techniques are often applied in order to perform this task automatically. The current bottleneck of transients detection in most surveys is the process of filtering numerous artifacts from candidate detection. We present a new method for automated artifact filtering based on hierarchical unsupervised classifier employing Self-Organizing Maps (SOMs). The system accepts 97% of real transients and removes 97.5% of artifacts when tested on the OGLE-IV Transient Detection System. The improvement of the artifacts filtering allows for single-frame-based detection of transients within OGLE-IV, which now alerts on transient discoveries in less than 15 minutes from the image acquisition.

  15. Single Trial Analysis of ERP Using Test Technique and Difference Evaluation of Modulated Vibratory Stimuli

    NASA Astrophysics Data System (ADS)

    Uchida, Masafumi; Nozawa, Akio; Ide, Hideto

    The purpose of this study is to develop the tactile display which consists of a single vibrator by using the modulated vibration. To achieve this purpose, we must evaluate the stimulus difference of the tactile in the modulated vibratory stimuli. In this study, the stimulus difference has been estimated by detecting the P300 wave in the averaged waveform of the ERP. However, it is indispensable to evaluate the stimulus difference efficiently to make the differential limen in the frequency region to express the modulated vibration clear. In this paper, the single trial analysis on the ERP that the significant difference of the EEG before and after the stimulus presentation is evaluated by the test technique is proposed.

  16. A cross-bridge based model of force depression: Can a single modification address both transient and steady-state behaviors?

    PubMed

    Corr, David T; Herzog, Walter

    2016-03-21

    Force depression (FD), the reduction of isometric force following active shortening, is a phenomenon of skeletal muscle that has received significant attention in biomechanical and physiological literature, yet the mechanisms underlying FD remain unknown. Recent experiments identified a slower rate of force redevelopment with increasing amounts of steady-state FD, suggesting that FD may be caused, at least in part, by a decrease in cross-bridge binding rate (Corr and Herzog, 2005; Koppes et al., 2014). Herein, we develop a cross-bridge based model of FD in which the binding rate function, f, decreases with the mechanical work performed during shortening. This modification incorporates a direct relationship between steady-state FD and muscle mechanical work (Corr and Herzog, 2005; Herzog et al., 2000; Kosterina et al., 2008), and is consistent with a proposed mechanism attributing FD to stress-induced inhibition of cross-bridge attachments (Herzog, 1998; Maréchal and Plaghki, 1979). Thus, for an increase in mechanical work, the model should predict a slower force redevelopment (decreased attachment rate) to a more depressed steady-state force (fewer attached cross-bridges), and a reduction in contractile element stiffness (Ford et al., 1981). We hypothesized that since this modification affects the cross-bridge kinetics, a corresponding model would be able to account for both transient and steady-state FD behaviors. Comparisons to prior experiments (Corr and Herzog, 2005; Herzog et al., 2000; Kosterina et al., 2008) show that both steady-state and transient aspects of FD, as well as the relationship of FD with respect to speed and amplitude of shortening, are well captured by this model. Thus, this relatively simple cross-bridge based model of FD lends support to a mechanism involving the inhibition of cross-bridge binding, and indicates that cross-bridge kinetics may play a critical role in FD. PMID:26928777

  17. Transient characteristics of rocket turbopumps

    NASA Astrophysics Data System (ADS)

    Shimura, Takashi; Watanabe, Mitsuo

    Transient characteristics of high-speed, high-pressure cryogenic turbopumps for rocket engines were examined experimentally by starting and stopping several rocket turbopumps rapidly by gas turbine drive. Aspects of transient characteristics studied were instantaneous pump head coefficient and pump efficiency, cavitation growth in the inducer during rapid acceleration, effects of the starting mode related to the propulsion system mission, and transient behavior of a self-balancing type axial thrust balancing system. Based on the test results, the feasibility of definite starting modes for the LE-5 turbopump was confirmed and the self-balancing type axial thrust balancing system for the LE-7 LOX turbopump was completed.

  18. A comparison of single-cycle versus multiple-cycle proof testing strategies

    NASA Technical Reports Server (NTRS)

    Hudak, S. J., Jr.; Mcclung, R. C.; Bartlett, M. L.; Fitzgerald, J. H.; Russell, D. A.

    1990-01-01

    An evaluation of single-cycle and multiple-cycle proof testing (MCPT) strategies for SSME components is described. Data for initial sizes and shapes of actual SSME hardware defects are analyzed statistically. Closed-form estimates of the J-integral for surface flaws are derived with a modified reference stress method. The results of load- and displacement-controlled stable crack growth tests on thin IN-718 plates with deep surface flaws are summarized. A J-resistance curve for the surface-cracked configuration is developed and compared with data from thick compact tension specimens. The potential for further crack growth during large unload/reload cycles is discussed, highlighting conflicting data in the literature. A simple model for ductile crack growth during MCPT based on the J-resistance curve is used to study the potential effects of key variables. The projected changes in the crack size distribution during MCPT depend on the interactions between several key parameters, including the number of proof cycles, the nature of the resistance curve, the initial crack size distribution, the component boundary conditions (load vs. displacement control), and the magnitude of the applied load or displacement. The relative advantages of single-cycle and multiple-cycle proof testing appear to be specific, therefore, to individual component geometry, material, and loading.

  19. A numerical comparison with an exact solution for the transient response of a cylinder immersed in a fluid. [computer simulated underwater tests to determine transient response of a submerged cylindrical shell

    NASA Technical Reports Server (NTRS)

    Giltrud, M. E.; Lucas, D. S.

    1979-01-01

    The transient response of an elastic cylindrical shell immersed in an acoustic media that is engulfed by a plane wave is determined numerically. The method applies to the USA-STAGS code which utilizes the finite element method for the structural analysis and the doubly asymptotic approximation for the fluid-structure interaction. The calculations are compared to an exact analysis for two separate loading cases: a plane step wave and an exponentially decaying plane wave.

  20. Transient receptor potential cation channel A1 (TRPA1) mediates changes in heart rate variability following a single exposure to acrolein in mice

    EPA Science Inventory

    The data show that a single exposure to acrolein causes autonomic imbalance in mice through the TRPA1 sensor and subsequent cardiac dysfunction. Human and animal studies have shown that short-term air pollution exposure causes...

  1. Tomographic test of Bell's inequality for a time-delocalized single photon

    SciTech Connect

    D'Angelo, Milena; Zavatta, Alessandro; Parigi, Valentina; Bellini, Marco

    2006-11-15

    Time-domain balanced homodyne detection is performed on two well-separated temporal modes sharing a single photon. The reconstructed density matrix of the two-mode system is used to prove and quantify its entangled nature, while the Wigner function is employed for an innovative tomographic test of Bell's inequality based on the theoretical proposal by Banaszek and Wodkiewicz [Phys. Rev. Lett. 82, 2009 (1999)]. Provided some auxiliary assumptions are made, a clear violation of the Banaszek-Bell inequality is found.

  2. Design and cold-air test of single-stage uncooled turbine with high work output

    NASA Technical Reports Server (NTRS)

    Moffitt, T. P.; Szanca, E. M.; Whitney, W. J.; Behning, F. P.

    1980-01-01

    A solid version of a 50.8 cm single stage core turbine designed for high temperature was tested in cold air over a range of speed and pressure ratio. Design equivalent specific work was 76.84 J/g at an engine turbine tip speed of 579.1 m/sec. At design speed and pressure ratio, the total efficiency of the turbine was 88.6 percent, which is 0.6 point lower than the design value of 89.2 percent. The corresponding mass flow was 4.0 percent greater than design.

  3. Test results of a single aperture 10 tesla dipole model magnet for the Large Hadron Collider

    SciTech Connect

    Yamamoto, Akira; Shintomi, Takakazu; Kimura, Nobuhiro

    1996-07-01

    A single aperture dipole magnet has been developed with a design magnetic field of 10 tesla by using Nb-Ti/Cu conductor to be operated at 1.8 K in pressurized super fluid helium. The magnet features double shell coil design by using high keystone Rutherford cable and compact non-magnetic steel collars to be adaptable in split/symmetric coil/collar design for twin aperture dipoles. A design central magnetic field of 10 tesla has been successfully achieved in excitation at 1.95 K in pressurized superfluid helium. Test results of the magnet with a summary of the design and fabrication will be presented.

  4. Combining an Internal Pilot with an Interim Analysis for Single Degree of Freedom Tests

    PubMed Central

    Kairalla, John A.; Muller, Keith E.; Coffey, Christopher S.

    2010-01-01

    An internal pilot with interim analysis (IPIA) design combines interim power analysis (an internal pilot) with interim data analysis (two stage group sequential). We provide IPIA methods for single df hypotheses within the Gaussian general linear model, including one and two group t tests. The design allows early stopping for efficacy and futility while also re-estimating sample size based on an interim variance estimate. Study planning in small samples requires the exact and computable forms reported here. The formulation gives fast and accurate calculations of power, type I error rate, and expected sample size. PMID:21037942

  5. Testing the effect of transient Plio-Pleistocene barriers in monsoonal Australo-Papua: did mangrove habitats maintain genetic connectivity in the Black Butcherbird?

    PubMed

    Kearns, Anna M; Joseph, Leo; Omland, Kevin E; Cook, Lyn G

    2011-12-01

    Changes in climate and sea level are hypothesized to have promoted the diversification of biota in monsoonal Australia and New Guinea by causing repeated range disjunctions and restricting gene flow between isolated populations. Using a multilocus (one mtDNA locus, five nuclear introns) phylogeographic approach, we test whether populations of the mangrove and rainforest restricted Black Butcherbird (Cracticus quoyi) have diverged across several geographic barriers defined a priori for this region. Phylogeographic structure and estimates of divergence times revealed Plio-Pleistocene divergences and long-term restricted gene flow of populations on either side of four major geographic barriers between and within Australia and New Guinea. Overall, our data are consistent with the hypothesis that mesic-adapted species did not disperse across the open dry woodlands and grasslands that dominated the transient palaeo-landbridges during the Plio-Pleistocene despite the presence of mangrove forests that might have acted as dispersal corridors for mesic-adapted species. Our study offers one of the first multilocus perspectives on the impact of changes in climate and sea level on the population history of widespread species with disjunct ranges in Australia and New Guinea. PMID:22060632

  6. Gravitational independence of single-breath washout tests in recumbent dogs

    NASA Technical Reports Server (NTRS)

    Tomioka, Shinichi; Kubo, Susumu; Guy, Harold J. B.; Prisk, G. K.

    1988-01-01

    The effect of gravitational orientation in the mechanism of lung filling and emptying in dogs was examined by conducting simultaneously Ar-bolus and N2 single-breath washout tests (SBWTs) in 10 anesthetized dogs (prone and supine), with three of the dogs subjected to body rotation. Transpulmonary pressure was measured simultaneously, allowing identification of the lung volume above residual volume at which there was an inflection point in the pressure-volume curve. Combined resident gas and bolus SBWTs in recumbent dogs were found to be different from such tests in humans; in dogs, the regional distribution of ventilation was not primarily determined by gravity. The measurements did not make it possible to discern exact mechanisms of filling and emptying, but both processes appear to be related to lung, thorax, and mediastinum interactions and/or differences in regional mechanical properties of the lungs.

  7. Experimental study on the single event effects in pulse width modulators by laser testing

    NASA Astrophysics Data System (ADS)

    Wen, Zhao; Xiaoqiang, Guo; Wei, Chen; Hongxia, Guo; Dongsheng, Lin; Hanning, Wang; Yinhong, Luo; Lili, Ding; Yuanming, Wang

    2015-11-01

    This paper presents single event effect (SEE) characteristics of UC1845AJ pulse width modulators (PWMs) by laser testing. In combination with analysis to map PWM circuitry in the microchip dies, the typical SEE response waveforms for laser pulses located in different circuit blocks of UC1845AJ are obtained and the SEE mechanisms are analyzed. The laser SEE test results show that there are some differences in the SEE mechanisms of different circuit blocks, and phase shifts or changes in the duty cycles of few output pulses are the main SEE behaviors for UC1845AJ. In addition, a new SEE behavior which manifests as changes in the duty cycles of many output pulses is revealed. This means that an SEE hardened design should be considered.

  8. Experimental tests of a single-photon calorimeter for X-ray spectroscopy

    NASA Technical Reports Server (NTRS)

    Mccammon, D.; Moseley, S. H.; Mather, J. C.; Mushotzky, R. F.

    1984-01-01

    Tests have been made of a nondispersive spectroscopic X-ray detector which operates by measuring the temperature rise following absorption of a single photon. Thermal pulses from 6-keV X-rays have been observed, and the different amplitudes resulting from Mn K-alpha and K-beta events have been resolved. This device was assembled to make quantitative tests of theoretical calculations of the properties of such detectors, and its high heat capacity does not allow it to attain the very high resolution predicted for detectors made by more sophisticated, but still straightforward, techniques. Both the measured resolution of 270-eV full width at half maximum and the absolute amplitude of the response are consistent with predictions. Nonthermal effects in the thermistor limit the precision of this comparison to about 30 percent.

  9. Mathematical Model for Solute Transport in a Single Borehole Dipole Flow Tracer Test

    NASA Astrophysics Data System (ADS)

    Chen, J.; Chan, Y.; Liang, C.

    2007-12-01

    The basic design of a single-borehole dipole-flow tracer test involves a well with an injection and an extraction chamber separated by some vertical distance and isolated from one another both using an inflatable packer. The test utilizes a small pump to create a vertical dipole-flow field. After the flow field is stabilized and the pumping rate and drawdowns in these chambers are recorded, a tracer mass is introduced instantaneously into injection chamber and the concentration breakthrough curve is monitored in the extraction chamber. The horizontal hydraulic conductivity, the vertical hydraulic conductivity and longitudinal dispersivity can be determined by using an appropriate mathematical model to analyze the breakthrough curves and drawdowns in these chambers. Existing mathematical models based on streamtube approach are only effective for interpreting tracer tests under advective-dominated condition. Furthermore, these solutions are appropriate for generation of breakthrough curve in the extraction chamber only because the transverse dispersion term is neglected. This study presents a novel mathematical model for describing solute transport in a single-borehole dipole-flow tracer test. In developing the mathematical model, a steady-state analytical solution for drawdown distribution is first obtained and the radial and vertical components of pore velocity are determined. Subsequently, the two-dimensional advection-dispersion equation in cylindrical coordinates for describing tracer transport in a dipole-flow field is derived based on the second order dispersion tensor theory. The Laplace transformed finite difference technique is applied to solve the two-dimensional advection-dispersion equation in cylindrical coordinates with variable- dependent coefficients. The developed model has an advantage over the existing models because it can be valid under a wide range of longitudianl dispersivity. The novel mathematical model is applied to simulate the concentration contour in the aquifer and the breakthrough curves in the chambers. Moreover, a curve-fitting method is proposed to determine the longitudinal dispersivity.

  10. Summary of Group Development and Testing for Single Shell Tank Closure at Hanford

    SciTech Connect

    Harbour, John, R.

    2005-04-28

    This report is a summary of the bench-scale and large scale experimental studies performed by Savannah River National Laboratory for CH2M HILL to develop grout design mixes for possible use in producing fill materials as a part of Tank Closure of the Single-Shell Tanks at Hanford. The grout development data provided in this report demonstrates that these design mixes will produce fill materials that are ready for use in Hanford single shell tank closure. The purpose of this report is to assess the ability of the proposed grout specifications to meet the current requirements for successful single shell tank closure which will include the contracting of services for construction and operation of a grout batch plant. The research and field experience gained by SRNL in the closure of Tanks 17F and 20F at the Savannah River Site was leveraged into the grout development efforts for Hanford. It is concluded that the three Hanford grout design mixes provide fill materials that meet the current requirements for successful placement. This conclusion is based on the completion of recommended testing using Hanford area materials by the operators of the grout batch plant. This report summarizes the regulatory drivers and the requirements for grout mixes as tank fill material. It is these requirements for both fresh and cured grout properties that drove the development of the grout formulations for the stabilization, structural and capping layers.

  11. Single element injector cold flow testing for STME swirl coaxial injector element design

    NASA Technical Reports Server (NTRS)

    Hulka, J.; Schneider, J. A.

    1993-01-01

    An oxidizer-swirled coaxial element injector is being investigated for application in the Space Transportation Main Engine (STME). Single element cold flow experiments were conducted to provide characterization of the STME injector element for future analysis, design, and optimization. All tests were conducted to quiescent, ambient backpressure conditions. Spray angle, circumferential spray uniformity, dropsize, and dropsize distribution were measured in water-only and water/nitrogen flows. Rupe mixing efficiency was measured using water/sucrose solution flows with a large grid patternator for simple comparative evaluation of mixing. Factorial designs of experiment were used for statistical evaluation of injector geometrical design features and propellant flow conditions on mixing and atomization. Increasing the free swirl angle of the liquid oxidizer had the greatest influence on increasing the mixing efficiency. The addition of gas assistance had the most significant effect on reducing oxidizer droplet size parameters and increasing droplet size distribution. Increasing the oxidizer injection velocity had the greatest influence for reducing oxidizer droplet size parameters and increasing size distribution for non-gas assisted flows. Single element and multi-element subscale hot fire testing are recommended to verify optimized designs before committing to the STME design.

  12. Stress transfer in microdroplet tensile test: PVC-coated and uncoated Kevlar-29 single fiber

    NASA Astrophysics Data System (ADS)

    Zhenkun, Lei; Quan, Wang; Yilan, Kang; Wei, Qiu; Xuemin, Pan

    2010-11-01

    The single fiber/microdroplet tensile test is applied for evaluating the interfacial mechanics between a fiber and a resin substrate. It is used to investigate the influence of a polymer coating on a Kevlar-29 fiber surface, specifically the stress transfer between the fiber and epoxy resin in a microdroplet. Unlike usual tests, this new test ensures a symmetrical axial stress on the embedded fiber and reduces the stress singularity that appears at the embedded fiber entry. Using a homemade loading device, symmetrical tensile tests are performed on a Kevlar-29 fiber with or without polyvinylchloride (PVC) coating, the surface of which is in contact with two epoxy resin microdroplets during curing. Raman spectra on the embedded fiber are recorded by micro-Raman Spectroscopy under different strain levels. Then they are transformed to the distributions of fiber axis stress based on the relationship between stress and Raman shift. The Raman results reveal that the fiber axial stresses increase with the applied loads, and the antisymmetric interfacial shear stresses, obtained by a straightforward balance of shear-to-axial forces argument, lead to the appearance of shear stress concentrations at a distance to the embedded fiber entry. The load is transferred from the outer fiber to the embedded fiber in the epoxy microdroplet. As is observed by scanning electronic microscopy (SEM), the existence of a flexible polymer coating on the fiber surface reduces the stress transfer efficiency.

  13. Dynamical study of the transport properties of ?-Mo4O11 single crystals by use of the photoinduced transient thermoelectric effect

    NASA Astrophysics Data System (ADS)

    Sasaki, M.; Tai, G. X.; Tamura, S.; Inoue, M.

    1993-03-01

    The pulsed-laser-induced transient thermoelectric effect (TTE) and the static transport properties (resistivity, Hall coefficient, magnetoresistance, and thermopower) of a quasi-two-dimensional ?-Mo4O11 crystal have been measured over the time range 50 ns-2 ms and temperature range 4.2-300 K. The observed TTE voltages decay exponentially with time, showing relaxation processes with multiple relaxation times ?i (i=1-5) for thermal diffusions of photogenerated carriers (electrons and holes), from which we can evaluate the corresponding carrier mobilities ?i. The temperature dependences of both dynamic and static transport quantities show anomalies around the characteristic temperatures Tc1=105 K and Tc2=35 K; Tc1 is the well-known charge-density-wave (CDW) transition temperature, but for the latter no definitive x-ray evidence for a CDW transition is reported. However, using our dynamic data and the existing two-dimensional tight-binding model, together with our proposed nesting model of the Fermi surfaces and the CDW-related modifications of the electron and hole bands at Tc1 and Tc2, we have self-consistently calculated the temperature dependence of the dc transport quantities, in satisfactory agreement with the experiments.

  14. Transient global amnesia mimics: Transient epileptic amnesia.

    PubMed

    Nicastro, Nicolas; Picard, Fabienne; Assal, Frederic

    2014-01-01

    We describe the case of a 79-year-old patient referred for suspected transient global amnesia, after an episode of anterograde amnesia which lasted 90 min. An EEG, performed after the episode, showed bilateral temporal electrographic seizures, orienting the diagnosis toward a transient epileptic amnesia. Transient epileptic amnesia is defined by temporal lobe epilepsy characterized by recurrent transient amnestic episodes of 30-90 min in duration, sometimes associated with olfactory hallucinations or oral automatisms. Response to antiepileptic drugs is excellent. We would like to raise awareness toward this epileptic amnesia when facing atypical or recurrent transient amnestic episodes. PMID:25667881

  15. A Comparison of Three IRT Approaches to Examinee Ability Change Modeling in a Single-Group Anchor Test Design

    ERIC Educational Resources Information Center

    Paek, Insu; Park, Hyun-Jeong; Cai, Li; Chi, Eunlim

    2014-01-01

    Typically a longitudinal growth modeling based on item response theory (IRT) requires repeated measures data from a single group with the same test design. If operational or item exposure problems are present, the same test may not be employed to collect data for longitudinal analyses and tests at multiple time points are constructed with unique…

  16. A Comparison of Three IRT Approaches to Examinee Ability Change Modeling in a Single-Group Anchor Test Design

    ERIC Educational Resources Information Center

    Paek, Insu; Park, Hyun-Jeong; Cai, Li; Chi, Eunlim

    2014-01-01

    Typically a longitudinal growth modeling based on item response theory (IRT) requires repeated measures data from a single group with the same test design. If operational or item exposure problems are present, the same test may not be employed to collect data for longitudinal analyses and tests at multiple time points are constructed with unique

  17. Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing.

    PubMed

    Tice, R R; Agurell, E; Anderson, D; Burlinson, B; Hartmann, A; Kobayashi, H; Miyamae, Y; Rojas, E; Ryu, J C; Sasaki, Y F

    2000-01-01

    Atthe International Workshop on Genotoxicity Test Procedures (IWGTP) held in Washington, DC, March 25-26, 1999, an expert panel met to develop guidelines for the use of the single-cell gel (SCG)/Comet assay in genetic toxicology. The expert panel reached a consensus that the optimal version of the Comet assay for identifying agents with genotoxic activity was the alkaline (pH > 13) version of the assay developed by Singh et al. [1988]. The pH > 13 version is capable of detecting DNA single-strand breaks (SSB), alkali-labile sites (ALS), DNA-DNA/DNA-protein cross-linking, and SSB associated with incomplete excision repair sites. Relative to other genotoxicity tests, the advantages of the SCG assay include its demonstrated sensitivity for detecting low levels of DNA damage, the requirement for small numbers of cells per sample, its flexibility, its low costs, its ease of application, and the short time needed to complete a study. The expert panel decided that no single version of the alkaline (pH > 13) Comet assay was clearly superior. However, critical technical steps within the assay were discussed and guidelines developed for preparing slides with agarose gels, lysing cells to liberate DNA, exposing the liberated DNA to alkali to produce single-stranded DNA and to express ALS as SSB, electrophoresing the DNA using pH > 13 alkaline conditions, alkali neutralization, DNA staining, comet visualization, and data collection. Based on the current state of knowledge, the expert panel developed guidelines for conducting in vitro or in vivo Comet assays. The goal of the expert panel was to identify minimal standards for obtaining reproducible and reliable Comet data deemed suitable for regulatory submission. The expert panel used the current Organization for Economic Co-operation and Development (OECD) guidelines for in vitro and in vivo genetic toxicological studies as guides during the development of the corresponding in vitro and in vivo SCG assay guidelines. Guideline topics considered included initial considerations, principles of the test method, description of the test method, procedure, results, data analysis and reporting. Special consideration was given by the expert panel to the potential adverse effect of DNA degradation associated with cytotoxicity on the interpretation of Comet assay results. The expert panel also discussed related SCG methodologies that might be useful in the interpretation of positive Comet data. The related methodologies discussed included: (1) the use of different pH conditions during electrophoreses to discriminate between DNA strand breaks and ALS; (2) the use of repair enzymes or antibodies to detect specific classes of DNA damage; (3) the use of a neutral diffusion assay to identify apoptotic/necrotic cells; and (4) the use of the acellular SCG assay to evaluate the ability of a test substance to interact directly with DNA. The alkaline (pH > 13) Comet assay guidelines developed by the expert panel represent a work in progress. Additional information is needed before the assay can be critically evaluated for its utility in genetic toxicology. The information needed includes comprehensive data on the different sources of variability (e.g., cell to cell, gel to gel, run to run, culture to culture, animal to animal, experiment to experiment) intrinsic to the alkaline (pH > 3) SCG assay, the generation of a large database based on in vitro and in vivo testing using these guidelines, and the results of appropriately designed multilaboratory international validation studies. PMID:10737956

  18. Test Analysis Correlation of the Single Stringer Bending Tests for the Space Shuttle ET-137 Intertank Stringer Crack Investigation

    NASA Technical Reports Server (NTRS)

    Phillips, Dawn R.; Saxon, Joseph B.; Wingate, Robert J.

    2012-01-01

    On November 5, 2010, Space Shuttle mission STS-133 was scrubbed due to a hydrogen leak at the Ground Umbilical Carrier Plate (GUCP). After the scrub, a crack in the foam thermal protection system (TPS) was observed on the External Tank (ET) near the interface between the liquid oxygen (LOX) tank and the Intertank. When the damaged foam was removed, two 9-in. long cracks were found on the feet of Intertank stringer S7-2, and the stringer failure was the cause of the TPS crack. An investigation was conducted to determine the root cause of the cracks, establish a remedy/repair for the stringers, and provide flight rationale for the damaged tank, ET-137. The Space Transportation System (STS) Super Lightweight ET (SLWT) is comprised of two propellant tanks (an aft liquid hydrogen (LH2) tank and a forward LOX tank) and an Intertank. The Intertank serves as the structural connection between the two propellant tanks and also functions to receive and distribute all thrust loads from the solid rocket boosters . The Intertank is a stiffened cylinder structure consisting of eight mechanically joined panels (two integrally-stiffened, machined thrust panels to react the booster loads and six stringer-stiffened skin panels). There are one main ring frame, four intermediate ring frames, and forward and aft flange chords that mate to the respective propellant tanks.. The skin/stringer panels utilize external hat-section stringers that are mechanically attached with rivets along most of their length and with specialty fasteners, such as GP Lockbolts and Hi-Loks, at the forward and aft ends where the stringers attach to the flange chords. During the STS-133 Intertank stringer crack investigation, cracks were found on a total of five stringers. All of the cracks were at the LOX end, in the feet of the stringers, and near the forward fasteners (GP Lockbolts). Video of tanking for the November 5 launch attempt was used to determine that the TPS failure, and thus the stringer failure, occurred as the LOX liquid level crossed the LOX tank / Intertank interface ring frame. Hence, cryogenically-induced displacements were suspected as a contributing cause of the stringer cracks. To study the behavior of Intertank stringers subjected to similar displacements, static load tests of individual stringers, colloquially known as "single stringer bending tests" were performed. Approximately thirty stringers were tested, many of which were cut from the partially completed Intertank for what would have been ET-139. In addition to the tests, finite element (FE) analyses of the test configuration were also performed. In this paper, the FE analyses and test-analysis correlation for stringer test S6-8 are presented. Stringer S6-8 is a "short chord" configuration with no doubler panels.

  19. The Single Intradermal Cervical Comparative Test Interferes with Johne’s Disease ELISA Diagnostics

    PubMed Central

    Kennedy, Aideen E.; Da Silva, Ana T.; Byrne, Noel; Govender, Rodney; MacSharry, John; O’Mahony, Jim; Sayers, Riona G.

    2014-01-01

    Enzyme-linked immunosorbent assays (ELISA) of milk and serum samples are a routinely used method of screening herds for Mycobacterium avium subspecies paratuberculosis (MAP). Infection with MAP causes granulomatous enteritis of ruminants known as Johne’s disease (JD). The sensitivity (Se) and specificity (Sp) of MAP ELISAs leads to difficulties in the identification of both infected and infectious animals. Interference with MAP ELISA Se and Sp has been reported in MAP seronegative cows following administration of purified protein derivative (PPD) as part of intradermal testing for bovine tuberculosis (bTB). The aim of this study is to examine the impact of the single intradermal cervical comparative test (SICCT) for bTB, on both serum and milk MAP ELISA tests, in a herd containing both seropositive and seronegative cows pre-SICCT. A secondary objective is to provide appropriate timing of JD ELISA tests in relation to the SICCT. A herd of 139 cows were serum and milk sampled pre- and post-SICCT administration. Prior to SICCT, 6% of the herd tested seropositive for MAP using milk ELISA, with 8% positive on serum. ID Screen Paratuberculosis Indirect Screening Test (ID Vet) was used to screen the herd. Within 14 days of PPD administration, a significant increase in the prevalence of seropositive cows was recorded. Identical prevalence’s were recorded with both test matrices (39%). ELISA values remained significantly higher until day 43 post-SICCT in milk (P = 0.850), and day 71 in serum (P = 0.602). If the “new” positives detected post-bTB testing are deemed false positives due to generation of cross-reacting antibodies by administration of PPD, milk would appear a more suitable sample for JD ELISA testing within 2 months of SICCT. In summary, sampling for JD utilizing milk ELISA should be avoided in the 43-day period following PPD administration, with serum ELISA sampling avoided for an additional 28 days. PMID:25429289

  20. Single-Crystal NiAl-X Alloys Tested for Hot Corrosion

    NASA Technical Reports Server (NTRS)

    Nesbitt, James A.

    1999-01-01

    Single-crystal nickel aluminide (NiAl) has been investigated extensively throughout the last several years as a potential structural material in aero-gas turbine engines. The attractive features of NiAl in comparison to Ni-base superalloys include a higher melting point, lower density, higher thermal conductivity, and excellent oxidation resistance. However, NiAl suffers from a lack of ductility and fracture toughness at low temperatures and a low creep strength at high temperatures. Alloying additions of hafnium (Hf), gallium (Ga), titanium (Ti), and chromium (Cr) have each shown some benefit to the mechanical properties over that of the binary alloy. However, the collective effect of these alloying additions on the environmental resistance of NiAl-X was unclear. Hence, the present study was undertaken to examine the hot corrosion behavior of these alloys. A companion study examined the cyclic oxidation resistance of these alloys. Several single-crystal NiAl-X alloys (where X is Hf, Ti, Cr, or Ga) underwent hot corrosion testing in a Mach 0.3 burner rig at the NASA Lewis Research Center. Samples were tested for up to 300 1-hr cycles at a temperature of 900 C. It was found that increasing the Ti content from 1 to 5 at.% degraded the hot corrosion behavior. This decline in the behavior was reflected in high weight gains and large corrosion mound formation during testing (see the figures). However, the addition of 1 to 2 at.% Cr to alloys containing 4 to 5 at.% Ti appeared to greatly reduce the susceptibility of these alloys to hot corrosion attack and negated the deleterious effect of the increased Ti addition.

  1. Transient global amnesia.

    PubMed

    Arena, Julieta E; Rabinstein, Alejandro A

    2015-02-01

    Transient global amnesia (TGA) is a clinical syndrome characterized by the sudden onset of anterograde amnesia (the inability to encode new memories), accompanied by repetitive questioning, sometimes with a retrograde component, lasting up to 24 hours, without compromise of other neurologic functions. Herein, we review current knowledge on the epidemiology, pathophysiology, clinical diagnosis, and prognosis of TGA. For this review, we conducted a literature search of PubMed, with no date limitations, using the following search terms (or combinations of them): transient global amnesia, etiology, pathophysiology, venous hypertension, migraine, magnetic resonance imaging, computed tomography, electroencephalography, prognosis, and outcome. We also reviewed the bibliography cited in the retrieved articles. Transient global amnesia is a clinical diagnosis, and recognition of its characteristic features can avoid unnecessary testing. Several pathophysiologic mechanisms have been proposed (venous insufficiency, arterial ischemia, and migrainous or epileptic phenomena), but none of them has been proved to consistently explain cases of TGA. Brain imaging may be considered and electroencephalography is recommended when episodes are brief and recurrent, but otherwise no investigations are necessary in most cases. Data on long-term prognosis are limited, but available information suggests that the relapse rate is low, the risk of stroke and seizures is not considerably increased, and cognitive outcome is generally good. PMID:25659242

  2. Transient Receptor Potential Channel Polymorphisms Are Associated with the Somatosensory Function in Neuropathic Pain Patients

    PubMed Central

    Baron, Ralf; Maier, Christoph; Tölle, Thomas R.; Treede, Rolf-Detlef; Berthele, Achim; Faltraco, Frank; Flor, Herta; Gierthmühlen, Janne; Haenisch, Sierk; Huge, Volker; Magerl, Walter; Maihöfner, Christian; Richter, Helmut; Rolke, Roman; Scherens, Andrea; Üçeyler, Nurcan; Ufer, Mike; Wasner, Gunnar; Zhu, Jihong; Cascorbi, Ingolf

    2011-01-01

    Transient receptor potential channels are important mediators of thermal and mechanical stimuli and play an important role in neuropathic pain. The contribution of hereditary variants in the genes of transient receptor potential channels to neuropathic pain is unknown. We investigated the frequency of transient receptor potential ankyrin 1, transient receptor potential melastin 8 and transient receptor potential vanilloid 1 single nucleotide polymorphisms and their impact on somatosensory abnormalities in neuropathic pain patients. Within the German Research Network on Neuropathic Pain (Deutscher Forscbungsverbund Neuropathischer Schmerz) 371 neuropathic pain patients were phenotypically characterized using standardized quantitative sensory testing. Pyrosequencing was employed to determine a total of eleven single nucleotide polymorphisms in transient receptor potential channel genes of the neuropathic pain patients and a cohort of 253 German healthy volunteers. Associations of quantitative sensory testing parameters and single nucleotide polymorphisms between and within groups and subgroups, based on sensory phenotypes, were analyzed. Single nucleotide polymorphisms frequencies did not differ between both the cohorts. However, in neuropathic pain patients transient receptor potential ankyrin 1 710G>A (rs920829, E179K) was associated with the presence of paradoxical heat sensation (p = 0.03), and transient receptor potential vanilloid 1 1911A>G (rs8065080, I585V) with cold hypoalgesia (p = 0.0035). Two main subgroups characterized by preserved (1) and impaired (2) sensory function were identified. In subgroup 1 transient receptor potential vanilloid 1 1911A>G led to significantly less heat hyperalgesia, pinprick hyperalgesia and mechanical hypaesthesia (p = 0.006, p = 0.005 and p<0.001) and transient receptor potential vanilloid 1 1103C>G (rs222747, M315I) to cold hypaesthesia (p = 0.002), but there was absence of associations in subgroup 2. In this study we found no evidence that genetic variants of transient receptor potential channels are involved in the expression of neuropathic pain, but transient receptor potential channel polymorphisms contributed significantly to the somatosensory abnormalities of neuropathic pain patients. PMID:21468319

  3. Using latent class analysis to estimate the test characteristics of the γ-interferon test, the single intradermal comparative tuberculin test and a multiplex immunoassay under Irish conditions.

    PubMed

    Clegg, Tracy A; Duignan, Anthony; Whelan, Clare; Gormley, Eamonn; Good, Margaret; Clarke, John; Toft, Nils; More, Simon J

    2011-07-01

    Considerable effort has been devoted to improving the existing diagnostic tests for bovine tuberculosis (single intradermal comparative tuberculin test [SICTT] and γ-interferon assay [γ-IFN]) and to develop new tests. Previously, the diagnostic characteristics (sensitivity, specificity) have been estimated in populations with defined infection status. However, these approaches can be problematic as there may be few herds in Ireland where freedom from infection is guaranteed. We used latent class models to estimate the diagnostic characteristics of existing (SICTT and γ-IFN) and new (multiplex immunoassay [Enferplex-TB]) diagnostic tests under Irish field conditions where true disease status was unknown. The study population consisted of herds recruited in areas with no known TB problems (2197 animals) and herds experiencing a confirmed TB breakdown (2740 animals). A Bayesian model was developed, allowing for dependence between SICTT and γ-IFN, while assuming independence from the Enferplex-TB test. Different test interpretations were used for the analysis: SICTT (standard and severe interpretation), γ-IFN (a single interpretation), and a range of interpretations for the Enferplex-TB (level-1 [high sensitivity interpretation] to level-5 [high specificity interpretation]). The sensitivity and specificity (95% posterior credibility intervals; 95% PCI) of SICTT[standard] relative to Enferplex-TB[level-1] and γ-IFN were 52.9-60.8% and 99.2-99.8%, respectively. Equivalent estimates for γ-IFN relative to Enferplex-TB[level-1] and SICTT were 63.1-70.1% and 86.8-89.4%, respectively. Sensitivity of Enferplex-TB[level-1] (95% PCI: 64.8-71.9%) was superior to the SICTT[standard], and specificity of the Enferplex-TB[level-5] was superior to γ-IFN (95% PCI: 99.6-100.0%). These results provide robust measures of sensitivity and specificity under field conditions in Ireland and suggest that the Enferplex-TB test has the potential to improve on current diagnostics for TB infection in cattle. The extent of that potential will be assessed in further studies. PMID:21470800

  4. Predictions and observations of the thermal hydrological conditions in the Single Heater Test

    NASA Astrophysics Data System (ADS)

    Tsang, Y. W.; Birkholzer, J. T.

    1999-05-01

    The Single Heater Test (SHT) is one of two in-situ thermal tests included in the site characterization program for the potential underground nuclear waste repository at Yucca Mountain. Coupled thermal-hydrological-mechanical-chemical processes in the fractured rock mass around the heater were monitored by numerous sensors emplaced among 30 boreholes. Periodic active testing of cross-hole radar tomography, neutron logging, electrical resistivity tomography, and interference air permeability tests probed the change of moisture content in the rock mass. Thermal-hydrological processes in the SHT have been simulated using a 3-D numerical model and compared to the monitored data. The good agreement between the temperature data and simulated results indicates that the thermal-hydrological responses of the SHT in the 9 months of heating are well-represented by the coupled thermal-hydrological numerical model. The dominant heat transfer process is by conduction and the signature of vapor and liquid counter flow is subtle in the temperature data. The simulated result of a dry-out zone of about 1 m (at the end of the heating phase) around the heater hole, and a condensation zone of increased liquid saturation outside of the dry-out zone, is consistent with the radar tomography and air permeability data. Tomography data and post-test laboratory measurements indicate that the moisture content is larger below than above the heater horizon, suggesting gravity drainage of condensate in the fractures. Model studies show that gravity drainage occurs in simulations using the dual permeability conceptual model, but is absent in the effective-continuum model, where matrix and fractures are required to be in thermodynamic equilibrium at all times.

  5. Evaluation of testing strategies to identify infected animals at a single round of testing within dairy herds known to be infected with Mycobacterium avium ssp. paratuberculosis.

    PubMed

    More, S J; Cameron, A R; Strain, S; Cashman, W; Ezanno, P; Kenny, K; Fourichon, C; Graham, D

    2015-08-01

    As part of a broader control strategy within herds known to be infected with Mycobacterium avium ssp. paratuberculosis (MAP), individual animal testing is generally conducted to identify infected animals for action, usually culling. Opportunities are now available to quantitatively compare different testing strategies (combinations of tests) in known infected herds. This study evaluates the effectiveness, cost, and cost-effectiveness of different testing strategies to identify infected animals at a single round of testing within dairy herds known to be MAP infected. A model was developed, taking account of both within-herd infection dynamics and test performance, to simulate the use of different tests at a single round of testing in a known infected herd. Model inputs included the number of animals at different stages of infection, the sensitivity and specificity of each test, and the costs of testing and culling. Testing strategies included either milk or serum ELISA alone or with fecal culture in series. Model outputs included effectiveness (detection fraction, the proportion of truly infected animals in the herd that are successfully detected by the testing strategy), cost, and cost-effectiveness (testing cost per true positive detected, total cost per true positive detected). Several assumptions were made: MAP was introduced with a single animal and no management interventions were implemented to limit within-herd transmission of MAP before this test. In medium herds, between 7 and 26% of infected animals are detected at a single round of testing, the former using the milk ELISA and fecal culture in series 5 yr after MAP introduction and the latter using fecal culture alone 15 yr after MAP introduction. The combined costs of testing and culling at a single round of testing increases with time since introduction of MAP infection, with culling costs being much greater than testing costs. The cost-effectiveness of testing varied by testing strategy. It was also greater at 5 yr, compared with 10 or 15 yr, since MAP introduction, highlighting the importance of early detection. Future work is needed to evaluate these testing strategies in subsequent rounds of testing as well as accounting for different herd dynamics and different levels of herd biocontainment. PMID:26074225

  6. A Compendium of Recent Optocoupler Radiation Test Data

    NASA Technical Reports Server (NTRS)

    Label, K. A.; Kniffin, S. D.; Reed, R. A.; Kim, H. S.; Wert, J. L.; Oberg, D. L.; Normand, E.; Johnston, A. H.; Lum, G. K.; Koga, R.; Day, John H. (Technical Monitor)

    2000-01-01

    We present a compendium of optocoupler radiation test data including neutron, proton and heavy ion Displacement Damage (DD), Single Event Transients (SET) and Total Ionizing Dose (TID). Proton data includes ionizing and non-ionizing damage mechanisms.

  7. Fractal analysis of pressure transients in the Geysers Geothermal Field

    SciTech Connect

    Acuna, J.A.; Ershaghi, I.; Yortsos, Y.C.

    1992-01-01

    The conventionally accepted models for the interpretation of pressure transient tests in naturally fractured reservoirs usually involve simplistic assumptions regarding the geometry and transport properties of the fractured medium. Many single well tests in this type of reservoirs fail to show the predicted behavior for dual or triple porosity or permeability systems and cannot be explained by these models. This paper describes the application of a new model based on a fractal interpretation of the fractured medium. The approach, discussed elsewhere [2], [6], is applied to field data from The Geysers Geothermal Field. The objective is to present an alternative interpretation to well tests that characterizes the fractured medium in a manner more consistent with other field evidence. The novel insight gained from fractal geometry allows the identification of important characteristics of the fracture structure that feeds a particular well. Some simple models are also presented that match the field transient results.

  8. A Comparison of Single-Cycle Versus Multiple-Cycle Proof Testing Strategies

    NASA Technical Reports Server (NTRS)

    McClung, R. C.; Chell, G. G.; Millwater, H. R.; Russell, D. A.; Orient, G. E.

    1996-01-01

    Single-cycle and multiple-cycle proof testing (SCPT and MCPT) strategies for reusable aerospace propulsion system components are critically evaluated and compared from a rigorous elastic-plastic fracture mechanics perspective. Earlier MCPT studies are briefly reviewed. New J-integral estimation methods for semi-elliptical surface cracks and cracks at notches are derived and validated. Engineering methods are developed to characterize crack growth rates during elastic-plastic fatigue crack growth (FCG) and the tear-fatigue interaction near instability. Surface crack growth experiments are conducted with Inconel 718 to characterize tearing resistance, FCG under small-scale yielding and elastic-plastic conditions, and crack growth during simulated MCPT. Fractography and acoustic emission studies provide additional insight. The relative merits of SCPT and MCPT are directly compared using a probabilistic analysis linked with an elastic-plastic crack growth computer code. The conditional probability of failure in service is computed for a population of components that have survived a previous proof test, based on an assumed distribution of initial crack depths. Parameter studies investigate the influence of proof factor, tearing resistance, crack shape, initial crack depth distribution, and notches on the MCPT vs. SCPT comparison. The parameter studies provide a rational basis to formulate conclusions about the relative advantages and disadvantages of SCPT and MCPT. Practical engineering guidelines are proposed to help select the optimum proof test protocol in a given application.

  9. Effect of bronchoconstrictor aerosols on the alveolar plateau of the single breath O2 test

    PubMed Central

    Stanescu, D. C.; Teculescu, D. B.; Pacuraru, R.; Popa, V.

    1968-01-01

    In 17 subjects with bronchial asthma and chronic bronchitis measurements of the uneven ventilation using the single breath oxygen test, F.E.V.1·0 and V.C. were performed before and after acetylcholine or allergen nebulization. An increase of the alveolar slope was noticed in five out of the seven patients with induced bronchospasm and a decrease in the remaining two. In two other subjects moderate dyspnoea not reflected by spirographic tests was accompanied by a definite increase of the N2 gradient. One patient experienced a severe asthmatic attack after acetylcholine without significant increase of the N2 gradient. In the last seven subjects the spirographic tests were not impaired but the N2 gradient rose to a significant level in three. The various implications of these results are discussed. In one subject the alveolar nitrogen concentration decreased after acetylcholine with a concomitant increase in the residual volume. This finding was assumed to be the result of either a failure of inspired oxygen to mix with alveolar nitrogen or a decreased available lung space. PMID:5711771

  10. Crash tests of four identical high-wing single-engine airplanes

    NASA Technical Reports Server (NTRS)

    Vaughan, V. L., Jr.; Hayduk, R. J.

    1980-01-01

    Four identical four place, high wing, single engine airplane specimens with nominal masses of 1043 kg were crash tested at the Langley Impact Dynamics Research Facility under controlled free flight conditions. These tests were conducted with nominal velocities of 25 m/sec along the flight path angles, ground contact pitch angles, and roll angles. Three of the airplane specimens were crashed on a concrete surface; one was crashed on soil. Crash tests revealed that on a hard landing, the main landing gear absorbed about twice the energy for which the gear was designed but sprang back, tending to tip the airplane up to its nose. On concrete surfaces, the airplane impacted and remained in the impact attitude. On soil, the airplane flipped over on its back. The crash impact on the nose of the airplane, whether on soil or concrete, caused massive structural crushing of the forward fuselage. The liveable volume was maintained in both the hard landing and the nose down specimens but was not maintained in the roll impact and nose down on soil specimens.

  11. A Comparison of Single-Cycle Versus Multiple-Cycle Proof Testing Strategies

    NASA Technical Reports Server (NTRS)

    McClung, R. C.; Chell, G. G.; Millwater, H. R.; Russell, D. A.; Millwater, H. R.

    1999-01-01

    Single-cycle and multiple-cycle proof testing (SCPT and MCPT) strategies for reusable aerospace propulsion system components are critically evaluated and compared from a rigorous elastic-plastic fracture mechanics perspective. Earlier MCPT studies are briefly reviewed. New J-integral estimation methods for semielliptical surface cracks and cracks at notches are derived and validated. Engineering methods are developed to characterize crack growth rates during elastic-plastic fatigue crack growth (FCG) and the tear-fatigue interaction near instability. Surface crack growth experiments are conducted with Inconel 718 to characterize tearing resistance, FCG under small-scale yielding and elastic-plastic conditions, and crack growth during simulated MCPT. Fractography and acoustic emission studies provide additional insight. The relative merits of SCPT and MCPT are directly compared using a probabilistic analysis linked with an elastic-plastic crack growth computer code. The conditional probability of failure in service is computed for a population of components that have survived a previous proof test, based on an assumed distribution of initial crack depths. Parameter studies investigate the influence of proof factor, tearing resistance, crack shape, initial crack depth distribution, and notches on the MCPT versus SCPT comparison. The parameter studies provide a rational basis to formulate conclusions about the relative advantages and disadvantages of SCPT and MCPT. Practical engineering guidelines are proposed to help select the optimum proof test protocol in a given application.

  12. Preliminary Test Results from 650 MHz Single Cell Medium Beta Cavities for Project X

    SciTech Connect

    Marhauser, Frank; Kneisel, Peter; Burrill, Andrew; Kushnick, Peter; Rimmer, R. A.

    2011-07-01

    We have fabricated two single cell 650 MHz {beta}=0.61 cavities of a JLab design, which possibly can be used for the proposed Project X proton linac application. Both cavities were manufactured at JLab from RRR>250 niobium sheet of 4 mm thickness using standard techniques such as deep drawing, electron beam welding, buffered chemical polishing, hydrogen degassing heat treatment, high pressure ultrapure water rinsing and clean room assembly. Initially cavity no. 1 was -- after final surface treatment by buffered chemical polishing (BCP) -- measured without any provisions for stiffening. As expected, the pressure sensitivity and the Lorentz Force detuning coefficients were relatively high; however, the RF performance was very encouraging: the cavity exhibited a Q-value > 10{sup 11} at 1.6K, corresponding to a residual resistance of < 1.5 n{Omega} The initial gradient was limited to E{sub acc} ~ 18 MV/m, limited by field emission. In a subsequent test, the cavity was re-rinsed and stiffened up, resulting in a somewhat improved mechanical behavior, but no improvement in rf performance. The second cavity was also tested twice, before and after low temperature baking. The results from all tests are reported in this contribution.

  13. Leishmanin skin test in guinea pig with a single purified protein of Leishmania major.

    PubMed

    Khabiri, A R; Bagheri, F; Alimohammadian, M H; Assmar, M; Nadaf, S R

    2005-12-01

    A series of hybridomas was produced by fusion of SP2/0 myeloma cells with spleen cells of mice immunized with Leishmania major (L. major). The reactivity of secreted monoclonal antibodies (mAbs) was evaluated against available leishmanin antigen by enzyme linked immunosorbent assay. Only one hybridoma designated as 7F9 secreted IgG1 mAb which was shown to be reactive with leishmanin. This mAb was further tested against four species of Leishmania (L. donovani, L. tropica, L. infantum, L. major) and a recombinant gp63. Among the four species tested it was shown to be only reactive with promastigotes of L. major. The antigen recognized by this mAb was purified and analyzed from both sonicated and supernatant cultures of L. major by immunoaffinity chromatography and reverse phase high performance liquid chromatography. The purified antigen, which gave a single band of 56kDa on sodium dodecyl sulfate polyacrylamide gel electrophoresis elicited a strong delayed-type hypersensitivity (DTH) reaction in guinea pigs sensitized with L. major. It was almost of the same degree as that produced by leishmanin. These results suggest that an L. major-specific antigen is an alternative as a specific diagnostic skin test reagent, which could lead to a better understanding of the mechanism of DTH in L. major. PMID:16212955

  14. Additive Manufacturing Thermal Performance Testing of Single Channel GRCop-84 SLM Components

    NASA Technical Reports Server (NTRS)

    Garcia, Chance P.; Cross, Matthew

    2014-01-01

    The surface finish found on components manufactured by sinter laser manufacturing (SLM) is rougher (0.013 - 0.0006 inches) than parts made using traditional fabrication methods. Internal features and passages built into SLM components do not readily allow for roughness reduction processes. Alternatively, engineering literature suggests that the roughness of a surface can enhance thermal performance within a pressure drop regime. To further investigate the thermal performance of SLM fabricated pieces, several GRCop-84 SLM single channel components were tested using a thermal conduction rig at MSFC. A 20 kW power source running at 25% duty cycle and 25% power level applied heat to each component while varying water flow rates between 2.1 - 6.2 gallons/min (GPM) at a supply pressure of 550 to 700 psi. Each test was allowed to reach quasi-steady state conditions where pressure, temperature, and thermal imaging data were recorded. Presented in this work are the heat transfer responses compared to a traditional machined OHFC Copper test section. An analytical thermal model was constructed to anchor theoretical models with the empirical data.

  15. Compendium of Single-Event Latchup and Total Ionizing Dose Test Results of Commercial Analog to Digital Converters

    NASA Technical Reports Server (NTRS)

    Irom, Farokh; Agarwal, Shri G.

    2012-01-01

    This paper reports single-event latchup and total dose results for a variety of analog to digital converters targeted for possible use in NASA spacecraft's. The compendium covers devices tested over the last 15 years.

  16. Evaluating quantitative 3-D image analysis as a design tool for low enriched uranium fuel compacts for the transient reactor test facility: A preliminary study

    DOE PAGESBeta

    Kane, J. J.; van Rooyen, I. J.; Craft, A. E.; Roney, T. J.; Morrell, S. R.

    2016-02-05

    In this study, 3-D image analysis when combined with a non-destructive examination technique such as X-ray computed tomography (CT) provides a highly quantitative tool for the investigation of a material’s structure. In this investigation 3-D image analysis and X-ray CT were combined to analyze the microstructure of a preliminary subsized fuel compact for the Transient Reactor Test Facility’s low enriched uranium conversion program to assess the feasibility of the combined techniques for use in the optimization of the fuel compact fabrication process. The quantitative image analysis focused on determining the size and spatial distribution of the surrogate fuel particles andmore » the size, shape, and orientation of voids within the compact. Additionally, the maximum effect of microstructural features on heat transfer through the carbonaceous matrix of the preliminary compact was estimated. The surrogate fuel particles occupied 0.8% of the compact by volume with a log-normal distribution of particle sizes with a mean diameter of 39 μm and a standard deviation of 16 μm. Roughly 39% of the particles had a diameter greater than the specified maximum particle size of 44 μm suggesting that the particles agglomerate during fabrication. The local volume fraction of particles also varies significantly within the compact although uniformities appear to be evenly dispersed throughout the analysed volume. The voids produced during fabrication were on average plate-like in nature with their major axis oriented perpendicular to the compaction direction of the compact. Finally, the microstructure, mainly the large preferentially oriented voids, may cause a small degree of anisotropy in the thermal diffusivity within the compact. α∥/α⊥, the ratio of thermal diffusivities parallel to and perpendicular to the compaction direction are expected to be no less than 0.95 with an upper bound of 1.« less

  17. Definition of Capabilities Needed for a Single Event Effects Test Facility

    SciTech Connect

    Riemer, Bernie; Gallmeier, Franz X.

    2014-12-01

    The Federal Aviation Administration (FAA) is contemplating new regulations mandating testing of the vulnerability of flight-critical avionics to single event effects (SEE). A limited number of high-energy neutron test facilities currently serve the SEE industrial and institutional research community. The FAA recognizes that existing facilities have insufficient test capacity to meet new demand from such mandates; it desires more flexible irradiation capabilities to test complete, large systems and would like capabilities to address greater concerns for thermal neutrons. For this reason, the FAA funded this study by Spallation Neutron Source (SNS) staff with the ultimate aim of developing options for SEE test facilities using high-energy neutrons at the SNS complex. After an investigation of current SEE test practices and assessment of future testing requirements, three concepts were identified covering a range of test functionality, neutron flux levels, and fidelity to the atmospheric neutron spectrum. The costs and times required to complete each facility were also estimated. SEE testing is generally performed by accelerating the event rate to a point where the effects are still dominated by single events and double event causes of failures are negligible. In practice, acceleration factors of as high as 106 are applicable for component testing, whereas for systems testing acceleration factors of 104 seem to be the upper limit. It is strongly desirable that the irradiation facility be tunable over a large range of high-energy neutron fluxes of 102 - 104 n/cm²/s for systems testing and from 104 - 107 n/cm²/s for components testing. The most capable, most flexible, and highest-test-capacity option is a new stand-alone target station named the High-Energy neutron Test Station (HETS). It is also the most expensive option, with a cost to complete of approximately $100 million. Dual test enclosures would allow for simultaneous testing activity effectively doubling overall test capacity per HETS operating hour. Using about 1 kilowatt (kW) of proton power extracted from the accelerator before injection in the accumulator ring, its operation would be unnoticeable by neutron scattering users at the SNS target station. The H beam laser stripping technique would allow for control of beam power on the HETS target independent from power delivered to the SNS. Large systems with frontal areas of up to 1 x 2 m² could be accommodated with integral high-energy flux values (above 10 megaelectron-volt, or MeV) to at most 104 n/cm²/s; components could also be tested with flux levels to at most 107 n/cm²/s on beam sizes of up to 0.2 x 0.2 m². Selectable moderating material and neutron filters would allow tailoring of the neutron spectrum to user demands; charged particle deflectors could be switched to allow or deflect protons, pions, and muons. It is estimated that HETS would take 5 years to complete after award of contract, including engineering design and construction. Commissioning would take at least another 6 months. Interference with SNS principal operations was not considered in the construction time estimate; connection of the proton transport line and tunnel from the accelerator high energy beam transport (HEBT) and construction around existing site utilities would require careful planning and coordination with beam operations at the SNS. A high-energy (HE) neutron test facility using an available beam line on the SNS target station is a technically and financially attractive option. Inspired by the new ChipIR instrument on the ISIS TS 2 spallation source in the UK, a similar facility could be placed on an unused beam line in the SNS instrument hall [e.g., on beam line 8 (both A and B channels would be needed) or on beam line 10]. The performance would approach that of an HETS (~80%), but it would be operationally more limited, with only a single user at a time. Space is more limited, so the maximum system size would be about half of that in an HETS. Flexibility to tailor the spectrum would be somewhat more limited. While this concept was not as fully developed and characterized, preliminary work indicates very high HE flux levels should be possible, with ample thermal neutrons as well. Flux control would be more difficult than at HETS because proton power on target be whatever the SNS was operating at for neutron scattering. Neutron attenuation devices would have to be employed with as-yet undetermined control resolution. However, no new buildings would be needed, and the necessary utilities are already present in the SNS Experiment Hall. The estimated cost for a beam line option is around $15 million; the time to complete would be 3 years after award of contract, plus at least 6 months for commissioning. Interference of construction activities with SNS operations should be negligible. This option would require negotiation with the Department of Energy Basic Energy Sciences (BES) office -- the primary stakeholder of SNS -- for an application outside the usual scope of neutron scattering sciences. Furthermore, these presently open beam lines are highly desirable locations for proposed neutron scattering instruments and obtaining one of them for an SEE test facility will come only with persuasive and timely arguments to SNS leadership and the DOE BES. The third option is a tunnel extension/target cave facility providing the most basic system-level irradiation capability with minimal flexibility. Again not as well developed a concept as HETS, it would use a laser-stripping technique like an HETS, redirecting protons to a tunnel similar to the initial HETS proton transport tunnel. Indeed, this concept is intended to be upgradable to a full HETS facility. Only a small fraction of a watt of proton power would be used in this basic configuration, though. An uncooled target and primitive shielding arrangement would provide beam on modestly sized systems that must be placed in close proximity to the target. The neutron fluence would be less uniform over the system than with the HETS or the beam line option. A data acquisition room and support area would be located on the ground level; access to the target cave would be via elevator and/or stairway. As a result of the required excavation, new tunnel construction, shielding, data acquisition building, utilities, and other items, the estimated cost is $30 million. The time to complete is expected be more than 3 years; here again construction interference with SNS operations has not been accounted for, but it could have a significant impact.

  18. Single and multiple impact ignition of new and aged high explosives in the Steven Impact Test

    SciTech Connect

    Chidester, S K; DePiero, A H; Garza, R G; Tarver, C M

    1999-06-01

    Threshold impact velocities for ignition of exothermic reaction were determined for several new and aged HMX-based solid high explosives using three types of projectiles in the Steven Test. Multiple impact threshold velocities were found to be approximately 10% lower in damaged charges that did not react in one or more prior impacts. Projectiles with protrusions that concentrate the friction work in a small volume of explosive reduced the threshold velocities by approximately 30%. Flat projectiles required nearly twice as high velocities for ignition as rounded projectiles. Blast overpressure gauges were used for both pristine and damaged charges to quantitatively measure reaction violence. Reactive flow calculations of single and multiple impacts with various projectiles suggest that the ignition rates double in damaged charges.

  19. Analysis and testing of high entrainment single nozzle jet pumps with variable mixing tubes

    NASA Technical Reports Server (NTRS)

    Hickman, K. E.; Hill, P. G.; Gilbert, G. B.

    1972-01-01

    An analytical model was developed to predict the performance characteristics of axisymmetric single-nozzle jet pumps with variable area mixing tubes. The primary flow may be subsonic or supersonic. The computer program uses integral techniques to calculate the velocity profiles and the wall static pressures that result from the mixing of the supersonic primary jet and the subsonic secondary flow. An experimental program was conducted to measure mixing tube wall static pressure variations, velocity profiles, and temperature profiles in a variable area mixing tube with a supersonic primary jet. Static pressure variations were measured at four different secondary flow rates. These test results were used to evaluate the analytical model. The analytical results compared well to the experimental data. Therefore, the analysis is believed to be ready for use to relate jet pump performance characteristics to mixing tube design.

  20. Testing of HOM coupler designs on a single cell niobium cavity

    SciTech Connect

    Peter Kneisel; Gianluigi Ciovati; ganapati rao myneni; Genfa Wu; Jacek Sekutowicz

    2005-05-01

    Coaxial higher order mode (HOM) couplers were developed initially for HERA cavities and subsequently for TESLA cavities. They were adopted later for SNS and Jlab upgrade cavities. The principle of operation is the rejection of the fundamental mode by the tunable filter and the transmission of the HOMs. It has been recognized recently that for continuous wave or high duty factor applications of the TESLA coupler the output pick-up probe must stay superconducting in order to avoid its heating by the fundamental mode residual magnetic field leading to deterioration of the cavity quality factor. In addition, the thermal conduction of existing rf feedthrough designs is only marginally sufficient to keep even the niobium probe tip superconducting in cw operation. We have equipped a single-cell niobium cavity with the modified HOM couplers and tested the new designs by measuring Q vs Eacc behavior at 2 K for different feedthroughs and probe tip materials.

  1. Test of a single module of the J-PET scanner based on plastic scintillators

    NASA Astrophysics Data System (ADS)

    Moskal, P.; Niedźwiecki, Sz.; Bednarski, T.; Czerwiński, E.; Kapłon, Ł.; Kubicz, E.; Moskal, I.; Pawlik-Niedźwiecka, M.; Sharma, N. G.; Silarski, M.; Zieliński, M.; Zoń, N.; Białas, P.; Gajos, A.; Kochanowski, A.; Korcyl, G.; Kowal, J.; Kowalski, P.; Kozik, T.; Krzemień, W.; Molenda, M.; Pałka, M.; Raczyński, L.; Rudy, Z.; Salabura, P.; Słomski, A.; Smyrski, J.; Strzelecki, A.; Wieczorek, A.; Wiślicki, W.

    2014-11-01

    A Time of Flight Positron Emission Tomography scanner based on plastic scintillators is being developed at the Jagiellonian University by the J-PET collaboration. The main challenge of the conducted research lies in the elaboration of a method allowing application of plastic scintillators for the detection of low energy gamma quanta. In this paper we report on tests of a single detection module built out from the BC-420 plastic scintillator strip (with dimensions of 5×19×300 mm3) read out at two ends by Hamamatsu R5320 photomultipliers. The measurements were performed using collimated beam of annihilation quanta from the 68Ge isotope and applying the Serial Data Analyzer (Lecroy SDA6000A) which enabled sampling of signals with 50 ps intervals. The time resolution of the prototype module was established to be better than 80 ps (σ) for a single level discrimination. The spatial resolution of the determination of the hit position along the strip was determined to be about 0.93 cm (σ) for the annihilation quanta. The fractional energy resolution for the energy E deposited by the annihilation quanta via the Compton scattering amounts to σ(E) / E ≈ 0.044 /√{ E(MeV) } and corresponds to the σ(E) / E of 7.5% at the Compton edge.

  2. Single-column model for atmospheric radiation measurement sites: Model development and sensitivity test

    SciTech Connect

    Xu, Q.; Dong, M.

    1995-04-01

    A single-column model (SCM) is constructed by extracting the physical subroutines from the community climate model (CCMI) of the National Center for Atmospheric Research. Using observational data obtained from the Oklahoma Atmospheric Radiation Measurement (ARM) site and the National Weather Services, this SCM will perform diagnostic studies of radiation and cloud parameterizations. So far, the model has been tested with simulated data generated by CCM1 global runs. The global runs provide the SCM with initial and lateral boundary conditions that represent the Oklahoma ARM site. The preliminary results can be summarized as follows: the SCM can produce nearly the same results as the CCM1 if the lateral boundary conditions are precisely given from the spectral forms of representation of boundary fluxes; the SCM results are moderately sensitive to noise in the lateral boundary conditions. The SCM simulated temperature can (or cannot) closely follow the CCM1 global run if the noise in the lateral boundary fluxes is below (or above) 10% of the single level. The representativeness of the lateral boundary conditions seems crucial for the SCM simulations. When the advection term is calculated by using the central finite difference scheme from the gridded (instead of spectral) data produced by the CCM1 run, the SCM simulated temperature can differ significantly from that of the CCM1 global run.

  3. Single-String Integration Test Measurements of the NEXT Ion Engine Plume

    NASA Technical Reports Server (NTRS)

    Snyder, Aaron; Kamhawi, Hani; Patterson, Michael; Britton, Melissa

    2005-01-01

    Measurements were made of a 40 cm ion-thruster plume as part of the single-string-integration-test (SSIT) activity of Phase I of the NASA's Evolutionary Xenon Thruster (NEXT) project. The NEXT ion engine incorporates design improvements that extend NSTAR power levels and efficiencies. During SSIT, an engineering model (EM2) 40 cm engine was operated using an advanced xenon propellant system in combination with either a GRC power console or advanced power processing unit. Integral goals of the single-string phase were to characterize engine performance over the full input power range and to detail thruster operation within the specification of the NEXT throttle table. Plume diagnostics measurements of relative Xe(+) and Xe(++) currents were made using near-field and far-field ExB probes. Planar geometry faraday probes were used to obtain beam current density profiles. This paper reports on the characterization of the EM2 plume over a range of SSIT operating conditions, first with the advanced propellant management system teamed with the GRC power console and then with the power-processing unit.

  4. Modeling Single Well Injection-Withdrawal (SWIW) Tests for Characterization of Complex Fracture-Matrix Systems

    SciTech Connect

    Cotte, F.P.; Doughty, C.; Birkholzer, J.

    2010-11-01

    The ability to reliably predict flow and transport in fractured porous rock is an essential condition for performance evaluation of geologic (underground) nuclear waste repositories. In this report, a suite of programs (TRIPOLY code) for calculating and analyzing flow and transport in two-dimensional fracture-matrix systems is used to model single-well injection-withdrawal (SWIW) tracer tests. The SWIW test, a tracer test using one well, is proposed as a useful means of collecting data for site characterization, as well as estimating parameters relevant to tracer diffusion and sorption. After some specific code adaptations, we numerically generated a complex fracture-matrix system for computation of steady-state flow and tracer advection and dispersion in the fracture network, along with solute exchange processes between the fractures and the porous matrix. We then conducted simulations for a hypothetical but workable SWIW test design and completed parameter sensitivity studies on three physical parameters of the rock matrix - namely porosity, diffusion coefficient, and retardation coefficient - in order to investigate their impact on the fracture-matrix solute exchange process. Hydraulic fracturing, or hydrofracking, is also modeled in this study, in two different ways: (1) by increasing the hydraulic aperture for flow in existing fractures and (2) by adding a new set of fractures to the field. The results of all these different tests are analyzed by studying the population of matrix blocks, the tracer spatial distribution, and the breakthrough curves (BTCs) obtained, while performing mass-balance checks and being careful to avoid some numerical mistakes that could occur. This study clearly demonstrates the importance of matrix effects in the solute transport process, with the sensitivity studies illustrating the increased importance of the matrix in providing a retardation mechanism for radionuclides as matrix porosity, diffusion coefficient, or retardation coefficient increase. Interestingly, model results before and after hydrofracking are insensitive to adding more fractures, while slightly more sensitive to aperture increase, making SWIW tests a possible means of discriminating between these two potential hydrofracking effects. Finally, we investigate the possibility of inferring relevant information regarding the fracture-matrix system physical parameters from the BTCs obtained during SWIW testing.

  5. Crop and Substrate Tests with Single Use Rooting "Pillows" for the VEGGIE Plant Growth Hardware

    NASA Technical Reports Server (NTRS)

    Massa, Gioia; Newsham, Gerard; Caro, Janicce; Stutte, Gary; Morrow, Robert; Wheeler, Raymond

    2011-01-01

    VEGGIE is a small plant production chamber built by ORBITEC. This chamber can be collapsed for easy stowage and deployed in orbit. It is designed for gravity independent operation, and provides 0.17 square m of crop growth area with three primary subsystems: an LED light panel, extendable transparent Teflon bellows to enclose the plants, and a wicking reservoir. VEGGIE would provide the capability for astronauts to grow fresh foods for dietary supplementation. Initial planting concepts tested with the VEGGIE included direct seeding or plug placement on the reservoir surface. These options had issues of salt accumulation and eventual toxicity if the reservoir was filled with nutrient solution, and hardware reuse was limited due to sanitation. In response a rooting packet or "pillow" concept was developed: single-use bags of media containing time release fertilizer with a wicking surface contacting the VEGGIE reservoir. Pillows being tested are small electrostatic bags with a Nitex nylon mesh side, each holding 100 mL of dry media. Six pillows fit in one VEGGIE unit; however pillow size could vary depending on crop selected. Seeds can be planted directly in pillows and planted pillows can be hydrated in space as desired. Our goals were to define optimal media and crops for an ISS mission scenario. Plant tests in pillows were performed in a controlled environment chamber set to habitat-relevant conditions, and capillary reservoir analogs were utilized. Media tested within pillows included: a commercial peat-based potting mix, arcillite (calcined clay), perlite: vermiculite, and peat-based: arcillite blends. Testing included 15 types of leafy greens, snow pea, radish, and herbs. Media performance was crop dependent, but generally plants showed the greatest growth in the peat-based: arcillite mixes. Crops with the best performance in pillows were identified, and testing is underway with select leafy greens examining plant and microbial load response to repeated harvest. We plan to use findings from previous flight testing with media to evaluate the effects of capillary flow from the reservoir to pillows in microgravity.

  6. Transient and steady-state selection in the striatal microcircuit

    PubMed Central

    Tomkins, Adam; Vasilaki, Eleni; Beste, Christian; Gurney, Kevin; Humphries, Mark D.

    2014-01-01

    Although the basal ganglia have been widely studied and implicated in signal processing and action selection, little information is known about the active role the striatal microcircuit plays in action selection in the basal ganglia-thalamo-cortical loops. To address this knowledge gap we use a large scale three dimensional spiking model of the striatum, combined with a rate coded model of the basal ganglia-thalamo-cortical loop, to asses the computational role the striatum plays in action selection. We identify a robust transient phenomena generated by the striatal microcircuit, which temporarily enhances the difference between two competing cortical inputs. We show that this transient is sufficient to modulate decision making in the basal ganglia-thalamo-cortical circuit. We also find that the transient selection originates from a novel adaptation effect in single striatal projection neurons, which is amenable to experimental testing. Finally, we compared transient selection with models implementing classical steady-state selection. We challenged both forms of model to account for recent reports of paradoxically enhanced response selection in Huntington's disease patients. We found that steady-state selection was uniformly impaired under all simulated Huntington's conditions, but transient selection was enhanced given a sufficient Huntington's-like increase in NMDA receptor sensitivity. Thus our models provide an intriguing hypothesis for the mechanisms underlying the paradoxical cognitive improvements in manifest Huntington's patients. PMID:24478684

  7. Modeling Single Well Injection-Withdrawal (SWIW) Tests for Characterization of Complex Fracture-Matrix Systems

    NASA Astrophysics Data System (ADS)

    Cotte, F.; Doughty, C.; Birkholzer, J. T.

    2010-12-01

    An essential condition for performance evaluation of enhanced geothermal systems (EGS) resides in the ability to reliably predict fluid flow and heat transport in fractured porous rocks, where fast convection-dispersive transport through the fracture network can be strongly affected by heat conduction into the adjacent rock matrix. SWIW tests are single-well tracer tests that involve an initial period of fluid and tracer injection followed by a period of fluid withdrawal. As a result of the flow field reversal, the measured breakthrough curves tend to be less sensitive to advective heterogeneities and more sensitive to matrix diffusion and sorption, making this method very valuable in characterizing fracture-matrix interaction and evaluating matrix properties. In particular, we propose using SWIW tests before and after hydrofracking operations, to help assess the means by which hydrofracking increases permeability and enhances fracture-matrix interaction. In the present study, we have modeled single-well injection-withdrawal (SWIW) tests for non-sorbing and sorbing tracers, using the mixed Eulerian-Lagrangian transport simulator TRIPOLY, which solves tracer advection and dispersion in fracture networks together with solute exchange processes between the fractures and the porous matrix. Our simulations were conducted for hypothetical but workable SWIW test designs considering a variety of statistically generated 2D fracture-matrix systems. Parameter sensitivity studies were completed on three physical parameters of the rock matrix, namely porosity, diffusion coefficient and retardation coefficient, in order to investigate their impact on the fracture-matrix solute exchange process. Hydraulic fracturing, or hydrofracking, was modeled in two different ways, one by increasing the fracture aperture for flow and the other one by adding a new set of fractures to the fracture network. The results of all these different tests were analyzed by studying the population of matrix blocks, the tracer spatial distribution, and the breakthrough curves (BTCs), while performing mass balance checks to ensure numerical accuracy. The possibility of inferring from SWIW-test BTCs relevant information on the physical parameters of the fracture-matrix system was investigated. Our results clearly demonstrate the importance of matrix effects in the solute transport process. The sensitivity studies illustrate the increased importance of the matrix as providing a retardation mechanism as matrix porosity, diffusion coefficient, or retardation coefficient increase. Heat convection and conduction can be shown to be mathematically equivalent to advection, diffusion, and sorption of tracer, making these tracer studies directly useful for analysis of EGS. Interestingly, preliminary results before and after hydrofracking are insensitive to adding more fractures while somewhat sensitive to aperture increase, making SWIW tests a possible means of discriminating between these two potential hydrofracking effects. However, our base case fracture network is highly connected, potentially minimizing the effect of hydrofracking. Further study is needed using a sparser network to study hydrofracking under more realistic conditions.

  8. Single-well tracer push-pull test sensitivity w. r. to fracture aperture and spacing

    NASA Astrophysics Data System (ADS)

    Ghergut, I.; Behrens, H.; Karmakar, S.; Sauter, M.

    2012-04-01

    Dealing with a parallel-fracture system of infinite lateral extension, four characteristic regimes of tracer signal sensitivity w. r. to fracture aperture and w. r. to fracture spacing s (whose reciprocal defines fracture density, or the fluid-rock interface area per volume) can be identified during the pull phase of a single-well push-pull test, also depending upon the ratio between push-phase duration Tpush and a characteristic time scale Ts (defined by s2 / D = Ts , with D denoting the tracer's effective diffusion coefficient): early-time regime: tracer signals are sensitive w. r. to fracture aperture, but insensitive w. r. to fracture spacing; sensitivity w. r. to fracture aperture first increases, then decreases with Tpush / Ts (thus there will be an optimum in terms of to Tpush / Ts , at early pull times); mid-time regime: tracer signals are sensitive w. r. to fracture spacing, but insensitive w. r. to fracture aperture; sensitivity w. r. to fracture spacing increases with Tpush / Ts ; late-time regime: with increasing pull duration, tracer signals become increasingly insensitive w. r. to fracture spacing, while regaining sensitivity w. r. to fracture aperture; 'very late'-time regime: sensitivity w. r. to fracture aperture becomes independent upon Tpush / Ts . From these different regimes, some recommendations can be derived regarding the design and dimensioning of dual-tracer single-well push-pull tests for the specific purposes of geothermal reservoir characterization, using conservative solutes and heat as tracers. Acknowledgement: This study is funded by MWK Niedersachsen (Lower-Saxony's Science and Culture Ministry) and by Baker Hughes (Celle) within task unit 'G6' of the Collaborative Research Project 'gebo' (Geothermal Energy and High-Performance Drilling).

  9. Direct evidence of lateral hyporheic flows revealed through single well tracer dilution tests

    NASA Astrophysics Data System (ADS)

    Binley, A.; Ullah, S.; Landsdown, K.; Heathwaite, L.; Kaeser, D.; Heppell, K.; Trimmer, M.; Zhang, H.

    2010-12-01

    Characterising the spatial and temporal distribution of the magnitude and direction of subsurface water fluxes within the zone of groundwater - river interaction is essential for reliable estimation of the speciation and pattern of nutrient fluxes between the two contrasting water bodies. Most conventional experimental approaches (e.g. using vertical gradients derived from piezometer heads, or one dimensional temperature profiles) ignore the role of lateral flows within this environment and yet such fluxes clearly contribute to the conceptualisation of a hyporheic zone. Single well dilution (drift) tests have been widely used in hydrogeological studies as a means of determining local lateral flux estimates. However, the adoption of such approaches in groundwater - surface water investigations has been generally ignored. Here, we present the findings from two field campaigns in which over 100 piezometers, installed within the bed and banks of a 250m reach of the River Leith in Cumbria, UK, were monitored for the dilution of an injected salt tracer. The results reveal significant lateral flows, in particular in the shallow (20cm depth) and deep (100cm depth) piezometers. In contrast, lateral fluxes within the intermediate zone (50cm depth) appear generally much smaller and are of a similar level to those derived from tests conducted in local riparian piezometers. The observed lateral fluxes in the river bed units are of a similar order to vertical fluxes determined from vertical hydraulic gradients and slug test hydraulic conductivities. Our findings corroborate with observed natural tracer profiles from multi-level samplers at the site and suggest that the zone of mixing between surface water and groundwater is constrained to the upper few tens of centimetres at the site. Furthermore, the high spatial density of our tracer testing highlights the spatial variability of fluxes within the reach and, in particular, indicates transverse and longitudinal trends along the reach.

  10. Single-Pass Flow Through (SPFT) Testing of Fluidized-Bed Steam Reforming (FBSR) Waste Forms

    SciTech Connect

    Lorier, T. H.; Pareizs, J. M.; Jantzen, C. M.

    2005-08-15

    Two samples of fluidized-bed steam reforming (FBSR) mineral waste form product were subjected to single-pass flow-through (SPFT) testing. Sample LAW 1123 resulted from pilot-scale FBSR processing with a Hanford Envelope A low-activity waste (LAW) simulant. Sample SBW 1173 resulted from pilot-scale FBSR processing with an Idaho National Laboratory (INL) simulant commonly referred to as sodium-bearing waste (SBW). The pilot-scale waste forms were made at the Science and Technology Applications Research (STAR) facility in Idaho Falls, Idaho. The durability of the two FBSR waste forms was assessed via the SPFT test in this study. Both samples were multiphase mineral waste forms, so the SPFT test results provide an overall release rate from the multiple mineral species in each sample and are dependent on the amount of each phase present and the mineralogy of the phases present. SPFT testing was performed at temperatures of 25, 40, 70, and 90 C on LAW 1123, while SBW 1173 was only tested at 70 and 90 C. The 70 and 90 C data were compared to each other and the LAW-1123 results were compared to previous testing performed by the Pacific Northwest National Laboratory (PNNL) on a LAW Envelope C (high organic content) waste simulant. The objectives of this study were to obtain forward dissolution rate data for both STAR FBSR bed products (using SPFT tests). Also, a qualitative comparison of the FBSR bed products to a glass waste form (specifically the low-activity reference material (LRM) glass) was performed. For these comparisons, the relative surface areas of the FBSR and glass products had to be measured. Due to the more porous and irregular surface of FBSR bed products, the surface area of the bed products was determined using the Brunauer, Emmett, and Teller (BET) measurement method. The surface area of a glass is much smoother and the calculated geometric surface area is typically used for determining dissolution behavior. Presently there are no specifications or standard release rates that the FBSR tested materials have to meet, e.g. the data from the FBSR testing is normally used during subsequent Performance Assessment (PA) calculations. Since a PA calculation is not part of this study, the LAW and SBW steam reforming samples were compared to each other, to previous LAW FBSR SPFT results, and to the results from the LRM reference glass. The experimental durability data generated from this study suggests that an FBSR mineral waste form product would be an adequate alternative form to borosilicate glass. The tested FBSR mineral waste forms showed normalized release rates for matrix elements such as Si to be more than 200X slower than the LRM glass. However, further durability testing and mineral phase information is recommended to further substantiate these findings.

  11. Neuromuscular Evaluation With Single-Leg Squat Test at 6 Months After Anterior Cruciate Ligament Reconstruction

    PubMed Central

    Hall, Michael P.; Paik, Ronald S.; Ware, Anthony J.; Mohr, Karen J.; Limpisvasti, Orr

    2015-01-01

    Background: Criteria for return to unrestricted activity after anterior cruciate ligament (ACL) reconstruction varies, with some using time after surgery as the sole criterion—most often at 6 months. Patients may have residual neuromuscular deficits, which may increase the risk of ACL injury. A single-leg squat test (SLST) can dynamically assess for many of these deficits prior to return to unrestricted activity. Hypothesis: A significant number of patients will continue to exhibit neuromuscular deficits with SLST at 6 months after ACL reconstruction. Study Design: Cross-sectional study; Level of evidence, 3. Methods: Patients using a standardized accelerated rehabilitation protocol at their 6-month follow-up after primary ACL reconstruction were enrolled. Evaluation included bilateral SLST, single-leg hop distance, hip abduction strength, and the subjective International Knee Documentation Committee (IKDC) score. Results: Thirty-three patients were enrolled. Poor performance of the operative leg SLST was found in 15 of 33 patients (45%). Of those 15 patients, 7 (45%) had concomitant poor performance of the nonoperative leg compared with 2 of 18 patients (11%) in those who demonstrated good performance in the operative leg. The poor performers were significantly older (33.6 years) than the good performers (24.2 years) (P = .007). Those with poor performance demonstrated decreased hip abduction strength (17.6 kg operative leg vs 20.5 kg nonoperative leg) (P = .024), decreased single-leg hop distance (83.3 cm operative leg vs 112.3 cm nonoperative leg) (P = .036), and lower IKDC scores (67.9 vs 82.3) (P = .001). Conclusion: Nearly half of patients demonstrated persistent neuromuscular deficits on SLST at 6 months, which is when many patients return to unrestricted activity. Those with poor performance were of a significantly older age, decreased hip abduction strength, decreased single-leg hop distance, and lower IKDC subjective scores. Clinical Relevance: The SLST can be used to identify neuromuscular risk factors for ACL rupture. Many patients at 6 months have persistent neuromuscular deficits on SLST. Caution should be used when using time alone to determine when patients can return to unrestricted activity. PMID:26665033

  12. Prototype Test Results for the Single Photon Detection SLR2000 Satellite Laser Ranging System

    NASA Technical Reports Server (NTRS)

    Zagwodzki, Thomas W.; McGarry, Jan F.; Degnan, John J.; Cheek, Jack W.; Dunn, Peter J.; Patterson, Don; Donovan, Howard

    2004-01-01

    NASA's aging Satellite Laser Ranging (SLR) network is scheduled to be replaced over the next few years with a fully automated single photon detection system. A prototype of this new system, called SLR2000, is currently undergoing field trials at the Goddard Space Flight Center in Greenbelt, Maryland to evaluate photon counting techniques and determine system hardware, software, and control algorithm performance levels and limitations. Newly developed diode pumped microchip lasers and quadrant microchannel plate-based photomultiplier tubes have enabled the development of this high repetition rate single photon detection SLR system. The SLR2000 receiver threshold is set at the single photoelectron (pe) level but tracks satellites with an average signal level typically much less than 1 pe. The 2 kHz laser fire rate aids in satellite acquisition and tracking and will enable closed loop tracking by accumulating single photon count statistics in a quadrant detector and using this information to correct for pointing errors. Laser transmitter beamwidths of 10 arcseconds (FWHM) or less are currently being used to maintain an adequate signal level for tracking while the receiver field of view (FOV) has been opened to 40 arcseconds to accommodate point ahead/look behind angular offsets. In the near future, the laser transmitter point ahead will be controlled by a pair of Risley prisms. This will allow the telescope to point behind and enable closure of the receiver FOV to roughly match the transmitter beam divergence. Bandpass filters (BPF) are removed for night tracking operations while 0.2 nm or 1 nm filters are used during daylight operation. Both day and night laser tracking of Low Earth Orbit (LEO) satellites has been achieved with a laser transmitter energy of only 65 microjoules per pulse. Satellite tracking is presently limited to LEO satellites until the brassboard laser transmitter can be upgraded or replaced. Simultaneous tracks have also been observed with NASA s SLR standard, MOBLAS 7, for the purposes of data comparison and identification of biases. Work continues to optimize the receive optics; upgrade or replace the laser transmitter; calibrate the quadrant detector, the point ahead Risley prisms, and event timer verniers; and test normal point generation with SLR2000 data. This paper will report on the satellite tracking results to date, issues yet to be resolved, and future plans for the SLR2000 system.

  13. Single stars in the Hyades open cluster. Fiducial sequence for testing stellar and atmospheric models

    NASA Astrophysics Data System (ADS)

    Kopytova, Taisiya G.; Brandner, Wolfgang; Tognelli, Emanuele; Prada Moroni, Pier Giorgio; Da Rio, Nicola; Röser, Siegfried; Schilbach, Elena

    2016-01-01

    Context. Age and mass determinations for isolated stellar objects remain model-dependent. While stellar interior and atmospheric theoretical models are rapidly evolving, we need a powerful tool to test them. Open clusters are good candidates for this role. Aims: We aim to create a fiducial sequence of stellar objects for testing stellar and atmospheric models. Methods: We complement previous studies on the Hyades multiplicity by Lucky Imaging observations with the AstraLux Norte camera. This allows us to exclude possible binary and multiple systems with companions outside a 2-7 AU separation and to create a single-star sequence for the Hyades. The sequence encompasses 250 main-sequence stars ranging from A5V to M6V. Using the Tool for Astrophysical Data Analysis (TA-DA), we create various theoretical isochrones applying different combinations of interior and atmospheric models. We compare the isochrones with the observed Hyades single-star sequence on J vs. J-Ks, J vs. J-H, and Ks vs. H-Ks color-magnitude diagrams. As a reference we also compute absolute fluxes and magnitudes for all stars from X-ray to mid-infrared based on photometric measurements available in the literature(ROSAT X-ray, GALEX UV, APASS gri, 2MASS JHKs, and WISE W1 to W4). Results: We find that combinations of both PISA and DARTMOUTH stellar interior models with BT-Settl 2010 atmospheric models describe the observed sequence well. We use PISA in combination with BT-Settl 2010 models to derive theoretical predictions for physical parameters (Teff, mass, log g) of 250 single stars in the Hyades. The full sequence covers the mass range of 0.13-2.30 M⊙, and effective temperatures between 3060 K and 8200 K. Conclusions: Within the measurement uncertainties, the current generation of models agree well with the single-star sequence. The primary limitations are the uncertainties in the measurement of the distances to individual Hyades members, and uncertainties in the photometry. Gaia parallaxes, photometry, and spectroscopy will greatly reduce the uncertainties in particular at the lowest mass range, and will enable us to test model predictions with greater confidence. Additionally, a small (~0.05 mag) systematic offset can be noted in J vs. J-K and K vs. H-K diagrams - the observed sequence is shifted to redder colors than the theoretical predictions. Based on observations collected at the Centro Astronómico Hispano Alemán (CAHA) at Calar Alto, operated jointly by the Max-Planck Institut für Astronomie and the Instituto de Astrofísica de Andalucía (CSIC).Full Table 2 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/585/A7

  14. Prediction of BOS by the single-breath nitrogen test in double lung transplant recipients

    PubMed Central

    2011-01-01

    Background The present study analyses the ability of the alveolar slope of the single-breath nitrogen washout test (N2-slope) to diagnose and predict the development of the bronchiolitis obliterans syndrome (BOS). Methods We present a retrospective analysis of 61 consecutive bilateral lung or heart-lung transplant recipients who were followed at regular control visits during a three year follow-up. The operating characteristics of the N2-slope to diagnose BOS and potential BOS (BOS 0-p) and to predict BOS were determined based on cut off values of 95% specificity. Results The sensitivity of the N2-slope to identify BOS was 96%, and BOS 0-p 100%. The predictive ability to predict BOS with a N2-slope > 478% of the predicted normal was 56%, and if combined with a coincident FEV1 < 90% of the basal value, the predictive ability was 75%. Conclusions The predictive ability of either the N2-slope or of FEV1 to diagnose BOS is limited but the combination of the two appears useful. Follow-up protocols of bilateral lung and heart-lung transplant recipients should consider including tests sensitive to obstruction of the peripheral airways. PMID:22118771

  15. Sexual dimorphic features within extant great ape faciodental skeletal anatomy and testing the single species hypothesis.

    PubMed

    Cameron, D W

    1997-01-01

    This paper examines sexually dimorphic skeletal characters within the face and upper dentition of extant hominids (great ape), not including members of the Hominini. Specimens of Pan paniscus, Pan troglodytes, Gorilla gorilla, and Pongo pygmaeus are used to help identify likely sex specific characters for the Hominidae. The aim of this paper is to identify extant hominid faciodental sexual features which can be used to help sex fossil specimens. A morphometric and skeletal study of sexual variability demonstrates relatively diverse patterns of sexual variability within the extant hominids. In terms of morphometrics, P. paniscus is relatively non-dimorphic, while P. troglodytes, Gorilla and Pongo display a large degree of sexual dimorphism. In their respective skeletal anatomies, however, each has specific characters which tend to differentiate between the sexes. Some faciodental sex features are shown to be common amongst all four taxa and as such are likely to be important criteria for determining the sex of Miocene and Plio-Pleistocene fossil hominid specimens. The construction of extant great ape sexual ranges of variability are also important in helping to test the fossil ape single species hypotheses. The testing of sex and species ranges of variability should employ range based statistics not only because they are sample size independent, (relative to C.V.) but also because they are of low power. PMID:9428188

  16. Single Event Effects Test Results for Advanced Field Programmable Gate Arrays

    NASA Technical Reports Server (NTRS)

    Allen, Gregory R.; Swift, Gary M.

    2006-01-01

    Reconfigurable Field Programmable Gate Arrays (FPGAs) from Altera and Actel and an FPGA-based quick-turnApplication Specific Integrated Circuit (ASIC) from Altera were subjected to single-event testing using heavy ions. Both Altera devices (Stratix II and HardCopy II) exhibited a low latchup threshold (below an LET of 3 MeV-cm2/mg) and thus are not recommended for applications in the space radiation environment. The flash-based Actel ProASIC Plus device did not exhibit latchup to an effective LET of 75 MeV-cm2/mg at room temperature. In addition, these tests did not show flash cell charge loss (upset) or retention damage. Upset characterization of the design-level flip-flops yielded an LET threshold below 10 MeV-cm2/mg and a high LET cross section of about lxlO-6 cm2/bit for storing ones and about lxl0-7 cm2/bit for storing zeros . Thus, the ProASIC device may be suitable for critical flight applications with appropriate triple modular redundancy mitigation techniques.

  17. Scaling submillimeter single-cycle transients toward megavolts per centimeter field strength via optical rectification in the organic crystal OH1.

    PubMed

    Ruchert, Clemens; Vicario, Carlo; Hauri, Christoph P

    2012-03-01

    We present the generation of high-power single-cycle terahertz (THz) pulses in the organic salt crystal 2-[3-(4-hydroxystyryl)-5.5-dimethylcyclohex-2-enylidene]malononitrile or OH1. Broadband THz radiation with a central frequency of 1.5 THz (λ(c)=200 μm) and high electric field strength of 440 kV/cm is produced by optical rectification driven by the signal of a powerful femtosecond optical parametric amplifier. A 1.5% pump to THz energy conversion efficiency is reported, and pulse energy stability better than 1% RMS is achieved. An approach toward the realization of higher field strength is discussed. PMID:22378431

  18. Strategies to improve phase-stability of ultrafast swept source optical coherence tomography for single shot imaging of transient mechanical waves at 16 kHz frame rate

    NASA Astrophysics Data System (ADS)

    Song, Shaozhen; Wei, Wei; Hsieh, Bao-Yu; Pelivanov, Ivan; Shen, Tueng T.; O'Donnell, Matthew; Wang, Ruikang K.

    2016-05-01

    We present single-shot phase-sensitive imaging of propagating mechanical waves within tissue, enabled by an ultrafast optical coherence tomography (OCT) system powered by a 1.628 MHz Fourier domain mode-locked (FDML) swept laser source. We propose a practical strategy for phase-sensitive measurement by comparing the phases between adjacent OCT B-scans, where the B-scan contains a number of A-scans equaling an integer number of FDML buffers. With this approach, we show that micro-strain fields can be mapped with ˜3.0 nm sensitivity at ˜16 000 fps. The system's capabilities are demonstrated on porcine cornea by imaging mechanical wave propagation launched by a pulsed UV laser beam, promising non-contact, real-time, and high-resolution optical coherence elastography.

  19. Design and Experimental Test Plan for Hybrid Sulfur Single Cell Pressurized Electrolyzer

    SciTech Connect

    Steeper, T. J.; Steimke, J. L.

    2005-09-01

    The Hybrid Sulfur (HyS) process is one of the leading thermochemical cycles being studied as part of the DOE Nuclear Hydrogen Initiative (NHI). SRNL is conducting analyses and research and development for the Department of Energy on the HyS process. A conceptual design report and development plan for the HyS process was issued on April 1, 2005 [Buckner, et. al., 2005] , and a report on atmospheric testing of a sulfur dioxide depolarized electrolyzer (SDE), a major component of the HyS process, was issued on August 1, 2005 [Steimke, 2005]. The purpose of this report is to document work related to the design and experimental test plan for a pressurized SDE. Pressurized operation of the SDE is a key requirement for development of an efficient and cost-effective HyS process. The HyS process, a hybrid thermochemical cycle proposed and investigated in the 1970s and early 1980s by Westinghouse Electric Corporation, is a high priority candidate for NHI due to the potential for high efficiency and its relatively high level of technical maturity. It was demonstrated in laboratory experiments by Westinghouse in 1978. Process improvements and component advancements that build on that work are being pursued. One of the objectives of the current work is to develop the SDE in order to permit the demonstration of a closed-loop laboratory model of the HyS process. The heart of the HyS process for generating hydrogen is a bank of electrolyzers incorporating sulfur dioxide depolarized anodes. SRNL planned, designed, built and operated a facility for testing single cell electrolyzers at ambient temperature and near atmospheric pressure during the spring and summer of 2005. The major contribution of the SRNL work was the establishment of the proof-of-concept for utilizing the proton-exchange-membrane (PEM) cell design for the SDE operation. Since PEM cells are being extensively developed for automotive fuel cell use, they offer significant potential for cost-effective application for the HyS Process. This report discusses the modifications necessary to the existing SRNL sulfur dioxide depolarized electrolyzer test facility to allow testing at up to 80 C and 90 psig. Because of the need for significant additional equipment and the ability to infer performance results to higher pressures, it recommends delaying further modifications to support testing at up to 300 psig (the commercial goal) until other, higher priority technical issues are addressed. These issues include membrane material selection, component designs, catalyst type and loading, etc. The factors and rationale that should be considered in developing and executing a detailed test matrix for pressurized operation are also discussed. In addition, an electrolyzer assembly design has been developed to allow the testing of different Membrane Electrode Assemblies (MEA's) as part of the planned FY06 HyS Development Program to complete selection of component design specifications for the HyS electrolyzer. MEA's are used in PEM cells to allow intimate contact and minimal resistance between the electrodes and the electrolyte layer. The pressurized electrolyzer assembly presented in this report will facilitate rapid change-out and testing of various MEA designs as part of the electrolyzer development effort.

  20. Workshop on Radio Transients

    NASA Astrophysics Data System (ADS)

    Croft, Steve; Gaensler, Bryan

    2012-04-01

    abstract-type="normal">SummaryWe are entering a new era in the study of variable and transient radio sources. This workshop discussed the instruments and the strategies employed to study those sources, how they are identified and classified, how results from different surveys can be compared, and how radio observations tie in with those at other wavelengths. The emphasis was on learning what common ground there is between the plethora of on-going projects, how methods and code can be shared, and how best practices regarding survey strategy could be adopted. The workshop featured the four topics below. Each topic commenced with a fairly brief introductory talk, which then developed into discussion. By way of preparation, participants had been invited to upload and discuss one slide per topic to a wiki ahead of the workshop. 1. Telescopes, instrumentation and survey strategy. New radio facilities and on-going projects (including upgrades) are both studying the variability of the radio sky, and searching for transients. The discussion first centred on the status of those facilities, and on projects with a time-domain focus, both ongoing and planned, before turning to factors driving choices of instrumentation, such as phased array versus single pixel feeds, the field of view, spatial and time resolution, frequency and bandwidth, depth, area, and cadence of the surveys. 2. Detection, pipelines, and classification. The workshop debated (a) the factors that influence decisions to study variability in the (u,v) plane, in images, or in catalogues, (b) whether, and how much, pipeline code could potentially be shared between one project and another, and which software packages are best for different approaches, (c) how data are stored and later accessed, and (d) how transients and variables are defined and classified. 3. Statistics, interpretation, and synthesis. It then discussed how (i) the choice of facility and strategy and (ii) detection and classification schemes influence what is seen (in terms of types of object and rates) by different surveys, (iii) how results from different surveys could be compared, and (iv) how what we know from existing surveys drives choices (i) and (ii), particularly as regards finding new classes of object. 4. Multiwavelength approaches. The workshop concluded by discussing what information is needed from wavelengths other than radio in order to classify transients and variables adequately and predict their rates as a function of topics (1), (2) and (3). It asked what the constraints are on responding to, and issuing triggers for, follow-up observations, and how that might feed back into considerations for designing our telescopes and surveys.

  1. Single molecule bridge as a testing ground for using NGF outside of the steady current regime

    NASA Astrophysics Data System (ADS)

    Velický, B.; Kalvová, A.; Špička, V.

    2010-01-01

    The simplest nanoscopic system, a molecular bridge consisting of a molecular island with one or few electronic or vibronic levels coupled to non-interacting leads can be treated using non-equilibrium Green's functions (NGF). We follow the well known procedure of Jauho, Wingreen and Meir (JWM). In the present work, we concentrate on the little investigated transient behavior of the molecular bridge undergoing abrupt changes. The transient process depends on the initial conditions at a finite time which may incorporate initial correlations. As an example, we study the electron response to sudden connecting the molecule to one or both leads. To obtain explicit solutions, we neglect all interactions at the island, whose role is mimicked by the island-leads coupling. We explore this analogy and obtain a complete solution for the transient NGF for arbitrary “initial correlations” represented by off-diagonal coherences between the initial electron state of the island and of the leads. This direct one-electron solution is confronted with the field theoretic approach in the particular case of the switch-on states, for which the initial correlations result from the previous history of the system. This is formally captured by the partitioning-in-time of the NGF, which we combine with the JWM theory. It is the virtue of partitioning method to express the transient NGF in terms of the building blocks of stationary-state NGF with zero, one or both leads connected. The direct and the partitioning solutions are reduced explicitly from one to the other, clarifying thus the meaning of the singular terms of the self-energy for correlated initial conditions.

  2. CHARACTERIZATION TESTING AND ANALYSIS OF SINGLE CELL SO2 DEPOLARIZED ELECTROLYZER

    SciTech Connect

    Steimke, J; Timothy Steeper, T

    2006-09-15

    This document reports work performed at the Savannah River National Laboratory (SRNL) that further develops the use of a proton exchange membrane or PEM-type electrochemical cell to produce hydrogen via SO{sub 2}-depolarized water electrolysis. This work was begun at SRNL in 2005. This research is valuable in achieving the ultimate goal of an economical hydrogen production process based on the Hybrid Sulfur (HyS) Cycle. The HyS Process is a hybrid thermochemical cycle that may be used in conjunction with advanced nuclear reactors or centralized solar receivers to produce hydrogen by water-splitting. Like all other sulfur-based cycles, HyS utilizes the high temperature thermal decomposition of sulfuric acid to produce oxygen. The unique aspect of HyS is the generation of hydrogen in a water electrolyzer that is operated under conditions where dissolved sulfur dioxide depolarizes the anodic reaction, resulting in substantial voltage reduction. Sulfur dioxide is oxidized at the anode, producing sulfuric acid that is sent to the acid decomposition portion of the cycle. The focus of this work was to conduct single cell electrolyzer tests in order to prove the concept of SO{sub 2}-depolarization and to determine how the results can be used to evaluate the performance of key components of the HyS Process. A test facility for conducting SO{sub 2}-depolarized electrolyzer (SDE) testing was designed, constructed and commissioned. The maximum cell current is 50 amperes, which is equivalent to a hydrogen production rate of approximately 20 liters per hour. Feed to the anode of the electrolyzer is sulfuric acid solutions containing dissolved sulfur dioxide. The partial pressure of sulfur dioxide may be varied in the range of 1 to 6 atm (15 to 90 psia). Temperatures may be controlled in the range from ambient to 80 C. Hydrogen generated at the cathode of the cell is collected for the purpose of flow measurement and composition analysis. The test facility proved to be easy to operate, versatile, and reliable.

  3. Analysis of tracer and thermal transients during reinjection

    SciTech Connect

    Kocabas, I.

    1989-10-01

    This work studied tracer and thermal transients during reinjection in geothermal reserviors and developed a new technique which combines the results from interwell tracer tests and thermal injection-backflow tests to estimate the thermal breakthrough times. Tracer tests are essential to determine the degree of connectivity between the injection wells and the producing wells. To analyze the tracer return profiles quantitatively, we employed three mathematical models namely, the convection-dispersion (CD) model, matrix diffusion (MD) model, and the Avodnin (AD) model, which were developed to study tracer and heat transport in a single vertical fracture. We considered three types of tracer tests namely, interwell tracer tests without recirculation, interwell tracer tests with recirculation, and injection-backflow tracer tests. To estimate the model parameters, we used a nonlinear regression program to match tracer return profiles to the solutions.

  4. Study on a test of optical stochastic cooling scheme in a single pass beam line

    SciTech Connect

    Chattopadhyay, S.; Kim, C.; Massoletti, D.; Zholents, A.

    1997-01-01

    A feasibility study of an experiment to test the principle of optical stochastic cooling is presented. We propose to build a new beamline in the extraction area of the ALS Booster synchrotron, where we will include a bypass lattice similar to the lattice that could be used in the cooling insertion in a storage ring. Of course, in the single pass beamline we cannot achieve cooling, but we can test all the functions of the bypass lattice that are required to achieve cooling in a storage ring. As it is stated in, there are stringent requirements on the time-of-flight properties of the bypass lattice employed in a cooling scheme. The pathlengths of particle trajectories in the bypass must be fairly insensitive to the standard set of errors that usually affect the performance of storage rings. Namely, it is necessary to preserve all fluctuations in the longitudinal particle density within the beam from the beginning to the end of the bypass lattice with the accuracy of {lambda}/2{pi}, where A is the carrying (optical) wavelength. According to, cooling will completely vanish if a combined effect of all kinds of errors will produce a spread of the pathlengths of particle trajectories larger than {lambda}/2 and the cooling time will almost double if the spread of the pathlengths is {lambda}/2{pi}. At a first glance, {lambda}/2{pi} {approx_equal} 0.1/{mu}m is such a small value that satisfying this accuracy looks nearly impossible. However, simulations show that a carefully designed bypass can meet all the requirements even with rather conservative tolerance to errors.

  5. Validation of the Bayesian Alcoholism Test Compared to Single Biomarkers in Detecting Harmful Drinking

    PubMed Central

    Korzec, Sanne; Korzec, Alex; Conigrave, Katherine; Gisolf, Janneke; Tabakoff, Boris

    2009-01-01

    Aims: Conventional tests for alcohol dependence often fail to detect hazardous and harmful alcohol use (HHAU) accurately. We previously validated the Bayesian Alcoholism Test (BAT) for the detection of HHAU among males. This uses 15 biochemical and clinical variables, including questionnaire data to calculate the probability of harmful (>80 g alcohol/day), hazardous (40–80 g/day) and ‘moderate’ (<40 g/day) drinking. Here we investigate the BAT's diagnostic performance when more limited clinical data are available. Methods: The WHO/ISBRA Collaborative Project recruited subjects from the general community and alcohol dependence treatment services. We analysed data from male drinkers: 318 alcohol dependent, 220 heavy and 712 moderate drinkers. Drinking was assessed using the Alcohol-Use Disorders and Associated Disabilities Interview Schedule. Eight of 15 markers used in the original BAT could be extracted from the WHO/ISBRA dataset. Results: Comparing harmful to moderate drinkers, the area under the ROC curve for BAT (0.90) was significantly higher than that for CDT (0.82), GGT (0.77) and AST (0.76). Comparing hazardous to moderate drinkers, the area under the ROC curve for BAT (0.78) was significantly higher than that for AST (0.65) but not significantly higher than that for CDT (0.71) and GGT (0.70). For all 1250 subjects, the amount consumed correlated significantly better with BAT (0.65) than with CDT (0.52), GGT (0.44) or AST (0.40) alone. Conclusions: The BAT is more accurate than commonly used single biological markers in detecting harmful alcohol use, even when only half the input requirements are available. Computerized record keeping increases the practicality of use of algorithms in the detection of harmful drinking. PMID:19293144

  6. On The Way To Off-equatorial Charged Discs Near Compact Objects - Single Test Particles Approximation

    NASA Astrophysics Data System (ADS)

    Kovar, Jiri; Kopacek, O.; Karas, V.; Stuchlik, Z.

    2010-02-01

    We present our recent studies of charged particles motion out of the equatorial plane in strong gravitational and electromagnetic fields. Within the general relativistic approach, we have demonstrated that the interplay between gravitational and electromagnetic action may allow for stable off-equatorial circular motion along the so-called halo orbits near compact objects, such as rotating magnetic compact stars and Kerr black holes immersed in an asymptotically uniform magnetic field of external origin. Locations of halo orbits correspond to minima of the two-dimensional effective potential, which exhibits several qualitativelly different kinds of behaviour, reflecting the charge of moving particles and orientation of the motion. Along with the study of the halo motion itself, we have discussed the general motion in the related off-equatorial potential lobes, demonstrating its chaoticness or regularity in terms of the Poincaré surfaces of sections and recurrence plots. A possible outlook of this study is to build a single test particles model of putative circumpulsar discs consisting of charged dust particles. Institute of Physics and Astronomical Institute have been operated under the projects MSM 4781305903 and AV 0Z10030501, and further supported by the Centre for Theoretical Astrophysics LC06014 in the Czech Republic. JK, VK and ZS thank the Czech Science Foundation (ref. P209/10/P190, 205/07/0052, 202/09/0772). OK acknowledges the doctoral student program of the Czech Science Foundation (205/09/H033).

  7. COAXIAL HOM COUPLER DESIGNS TESTED ON A SINGLE CELL NIOBIUM CAVITY

    SciTech Connect

    Peter Kneisel; Gianluigi Ciovati; Genfa Wu; Jacek Sekutowicz

    2006-08-21

    Poster - Coaxial higher order mode (HOM) couplers have been developed for HERA cavities and are used in TESLA, SNS and JLab upgrade cavities. The principle of operation is the rejection of the fundamental mode by the tunable filter of the coupler and the transmission of the HOMs. It has been recognized recently that inappropriate thermal designs of the feed through for the pick-up probe of the HOM coupler will not sufficiently carry away the heat generated in the probe tip by the fundamental mode fields, causing a built-up of the heating of the niobium probe tip and subsequently, a deterioration of the cavity quality factor has been observed in CW operation. An improvement of the situation has been realized by a better thermal design of the feed through incorporating a sapphire rf window. An alternative is a modification of the coupler loop (?F? ? part) with an extension towards the pick-up probe. This design has been tested on a single cell niobium cavity in comparison to a 'standard TESLA' configuration by measuring the Eacc behavior at 2 K. The measurements clearly indicate that the modified version of the coupler loop is thermally much more stable than the standard version.

  8. Coaxial HOM Coupler designs tested on a single cell niobium cavity

    SciTech Connect

    Peter Kneisel; Genfa Wu; Gianluigi Ciovati; Jacek Sekutowicz

    2006-08-28

    Coaxial higher order mode (HOM) couplers have been developed for HERA cavities and are used in TESLA, SNS and JLab upgrade cavities. The principle of operation is the rejection of the fundamental mode by the tunable filter of the coupler and the transmission of the HOMs. It has been recognized recently that inappropriate thermal designs of the feedthrough for the pick-up probe of the HOM coupler will not sufficiently carry away the heat generated in the probe tip by the fundamental mode fields, causing a built-up of the heating of the niobium probe tip and subsequently, a deterioration of the cavity quality factor has been observed in CW operation. An improvement of the situation has been realized by a better thermal design of the feedthrough incorporating a sapphire rf window [1]. An alternative is a modification of the coupler loop (?F? ? part) with an extension towards the pick-up probe. This design has been tested on a single cell niobium cavity in comparison to a ''standard TESLA'' configuration by measuring the Eacc behavior at 2 K. The measurements clearly indicate that the modified version of the coupler loop is thermally much more stable than the standard version.

  9. TIA (Transient Ischemic Attack)

    MedlinePlus

    ... Know About Stroke TIA (Transient Ischemic Attack) Updated:Mar 28,2016 Excerpted from “ Why Rush? ”, Stroke Connection January/February 2009 (Science update October 2012) While transient ischemic attack (TIA) ...

  10. Transient drainage summary report

    SciTech Connect

    1996-09-01

    This report summarizes the history of transient drainage issues on the Uranium Mill Tailings Remedial Action (UMTRA) Project. It defines and describes the UMTRA Project disposal cell transient drainage process and chronicles UMTRA Project treatment of the transient drainage phenomenon. Section 4.0 includes a conceptual cross section of each UMTRA Project disposal site and summarizes design and construction information, the ground water protection strategy, and the potential for transient drainage.

  11. Comparison between single and combined post-treatment with S-Methyl-N,N-diethylthiolcarbamate sulfoxide and taurine following transient focal cerebral ischemia in rat brain.

    PubMed

    Gharibani, P; Modi, J; Menzie, J; Alexandrescu, A; Ma, Z; Tao, R; Prentice, H; Wu, J-Y

    2015-08-01

    We have recently reported on the efficacy of an N-methyl-d-aspartate (NMDA) receptor partial antagonist, S-Methyl-N,N-diethylthiolcarbamate sulfoxide (DETC-MeSO), in improving outcome following stroke, including reduced infarct size and calcium influx, suppressing the endoplasmic reticulum (ER) stress-induced apoptosis as well as improving behavioral outcome. DETC-MeSO was shown to suppress the protein kinase R-like endoplasmic reticulum kinase (PERK) pathway, one of the major ER stress pathways. Several studies including ours have provided evidence that taurine also has neuroprotective effects through reducing apoptosis and inhibiting activating transcription factor 6 (ATF6) and inositol requiring enzyme 1 (IRE-1) pathways. We hypothesized that a combined treatment with DETC-MeSO and taurine would ameliorate ischemia-induced brain injury by inhibiting all three ER stress pathways. Twenty four hours following reperfusion of a 2-h ischemic stroke, rats received either 0.56-mg/kg DETC-MeSO or 40-mg/kg of taurine, either alone or in combination, subcutaneously for 4days. Our study showed that combined DETC-MeSO and taurine, but not DETC-MeSO alone at the dose used, greatly reduced the infarct size, improved performance on the neuro-score test and attenuated proteolysis of αII-spectrin. Meanwhile, the level of the pro-apoptotic protein, Bax, declined and the anti-apoptotic protein, B-cell lymphoma 2 (BCL-2), expression was markedly increased. Combination therapy decreased both caspase-12 and caspase-3 activation by preventing the release of Cytochrome-c from mitochondria, indicating attenuation of apoptosis in ischemic infarct. Glucose-regulated protein (GRP)78 as a marker of the unfolded protein response decreased and levels of the key ER stress protein markers p-PERK-ATF4, p-eIF2α and cleaved-ATF-6 were found to significantly decline. NeuN expression levels indicated that more neurons were protected in the presence of DETC-MeSO and taurine. We also showed that combined treatment can prevent gliosis and increase p-AKT a pro-survival marker in the penumbra. Therefore, we conclude that combined treatment with both DETC-MeSO and taurine synergistically inhibits all three ER stress pathways and apoptosis and therefore can be a novel and effective treatment after ischemic stroke. PMID:26022360

  12. Transient effects in turbulence modelling

    SciTech Connect

    Boyle, D.R.; Golay, M.W.

    1980-06-01

    Measurements of turbulence field data are reported for recirculating water flows under steady-state and transient flow conditions in an improved 1/15 scale FFTF outlet plenum test-cell. A dual-channel Laser Doppler Anemometer is used, and a unique method for performing transient measurements is developed and analyzed. The experimental behavior is predicted with a modified version of the VARR-II fluid dynamics code, and the suitability of using the steady-state turbulence model closure assumptions for analysis of transient flows is evaluated. A relationship between K-sigma and K-epsilon turbulence models is derived, and the two models are found to be nearly equivalent.

  13. Fracture trace map and single-well aquifer test results in a carbonate aquifer in Berkeley County, West Virginia

    USGS Publications Warehouse

    McCoy, Kurt J.; Podwysocki, Melvin H.; Crider, E. Allen; Weary, David J.

    2005-01-01

    These data contain information on the results of single-well aquifer tests, lineament analysis, and a bedrock geologic map compilation for the low-lying carbonate and shale areas of eastern Berkeley County, West Virginia. Efforts have been initiated by management agencies of Berkeley County in cooperation with the U.S. Geological Survey to further the understanding of the spatial distribution of fractures in the carbonate regions and their correlation with aquifer properties. This report presents transmissivity values from about 200 single-well aquifer tests and a map of fracture-traces determined from aerial photos and field investigations. Transmissivity values were compared to geologic factors possibly affecting its magnitude.

  14. Single-Event Effects Ground Testing and On-Orbit Rate Prediction Methods: The Past, Present and Future

    NASA Technical Reports Server (NTRS)

    Reed, Robert A.; Kinnison, Jim; Pickel, Jim; Buchner, Stephen; Marshall, Paul W.; Kniffin, Scott; LaBel, Kenneth A.

    2003-01-01

    Over the past 27 years, or so, increased concern over single event effects in spacecraft systems has resulted in research, development and engineering activities centered around a better understanding of the space radiation environment, single event effects predictive methods, ground test protocols, and test facility developments. This research has led to fairly well developed methods for assessing the impact of the space radiation environment on systems that contain SEE sensitive devices and the development of mitigation strategies either at the system or device level.

  15. SEU and Test Considerations for FPGA Devices

    NASA Technical Reports Server (NTRS)

    Berg, Malanie

    2006-01-01

    This viewgraph presentation provides an overview of Field Programmable Gate Arrays (FPGAs), what they are, implementations in space missions, and current available technologies. Single Event Upsets (SEUs) and Single Event Transients (SETs) are discussed in relation to their effects on FPGAs. Testing goals, considerations, and data analysis are reviewed.

  16. Validation of a Pressure-Based Combustion Simulation Tool Using a Single Element Injector Test Problem

    NASA Technical Reports Server (NTRS)

    Thakur, Siddarth; Wright, Jeffrey

    2006-01-01

    The traditional design and analysis practice for advanced propulsion systems, particularly chemical rocket engines, relies heavily on expensive full-scale prototype development and testing. Over the past decade, use of high-fidelity analysis and design tools such as CFD early in the product development cycle has been identified as one way to alleviate testing costs and to develop these devices better, faster and cheaper. Increased emphasis is being placed on developing and applying CFD models to simulate the flow field environments and performance of advanced propulsion systems. This necessitates the development of next generation computational tools which can be used effectively and reliably in a design environment by non-CFD specialists. A computational tool, called Loci-STREAM is being developed for this purpose. It is a pressure-based, Reynolds-averaged Navier-Stokes (RANS) solver for generalized unstructured grids, which is designed to handle all-speed flows (incompressible to hypersonic) and is particularly suitable for solving multi-species flow in fixed-frame combustion devices. Loci-STREAM integrates proven numerical methods for generalized grids and state-of-the-art physical models in a novel rule-based programming framework called Loci which allows: (a) seamless integration of multidisciplinary physics in a unified manner, and (b) automatic handling of massively parallel computing. The objective of the ongoing work is to develop a robust simulation capability for combustion problems in rocket engines. As an initial step towards validating this capability, a model problem is investigated in the present study which involves a gaseous oxygen/gaseous hydrogen (GO2/GH2) shear coaxial single element injector, for which experimental data are available. The sensitivity of the computed solutions to grid density, grid distribution, different turbulence models, and different near-wall treatments is investigated. A refined grid, which is clustered in the vicinity of the solid walls as well as the flame, is used to obtain a steady state solution which may be considered as the best solution attainable with the steady-state RANS methodology. From a design point of view, quick turnaround times are desirable; with this in mind, coarser grids are also employed and the resulting solutions are evaluated with respect to the fine grid solution.

  17. Local strain and damage mapping in single trabeculae during three-point bending tests.

    PubMed

    Jungmann, R; Szabo, M E; Schitter, G; Tang, Raymond Yue-Sing; Vashishth, D; Hansma, P K; Thurner, P J

    2011-05-01

    The use of bone mineral density as a surrogate to diagnose bone fracture risk in individuals is of limited value. However, there is growing evidence that information on trabecular microarchitecture can improve the assessment of fracture risk. One current strategy is to exploit finite element analysis (FEA) applied to 3D image data of several mm-sized trabecular bone structures obtained from non-invasive imaging modalities for the prediction of apparent mechanical properties. However, there is a lack of FE damage models, based on solid experimental facts, which are needed to validate such approaches and to provide criteria marking elastic-plastic deformation transitions as well as microdamage initiation and accumulation. In this communication, we present a strategy that could elegantly lead to future damage models for FEA: direct measurements of local strains involved in microdamage initiation and plastic deformation in single trabeculae. We use digital image correlation to link stress whitening in bone, reported to be correlated to microdamage, to quantitative local strain values. Our results show that the whitening zones, i.e. damage formation, in the presented loading case of a three-point bending test correlate best with areas of elevated tensile strains oriented parallel to the long axis of the samples. The average local strains along this axis were determined to be (1.6±0.9)% at whitening onset and (12±4)% just prior to failure. Overall, our data suggest that damage initiation in trabecular bone is asymmetric in tension and compression, with failure originating and propagating over a large range of tensile strains. PMID:21396601

  18. Local strain and damage mapping in single trabeculae during three-point bending tests

    PubMed Central

    Jungmann, R.; Szabo, M.E.; Schitter, G.; Tang, Raymond Yue-Sing; Vashishth, D.; Hansma, P.K.; Thurner, P.J.

    2012-01-01

    The use of bone mineral density as a surrogate to diagnose bone fracture risk in individuals is of limited value. However, there is growing evidence that information on trabecular microarchitecture can improve the assessment of fracture risk. One current strategy is to exploit finite element analysis (FEA) applied to 3D image data of several mm-sized trabecular bone structures obtained from non-invasive imaging modalities for the prediction of apparent mechanical properties. However, there is a lack of FE damage models, based on solid experimental facts, which are needed to validate such approaches and to provide criteria marking elastic–plastic deformation transitions as well as microdamage initiation and accumulation. In this communication, we present a strategy that could elegantly lead to future damage models for FEA: direct measurements of local strains involved in microdamage initiation and plastic deformation in single trabeculae. We use digital image correlation to link stress whitening in bone, reported to be correlated to microdamage, to quantitative local strain values. Our results show that the whitening zones, i.e. damage formation, in the presented loading case of a three-point bending test correlate best with areas of elevated tensile strains oriented parallel to the long axis of the samples. The average local strains along this axis were determined to be (1.6 ± 0.9)% at whitening onset and (12 ± 4)% just prior to failure. Overall, our data suggest that damage initiation in trabecular bone is asymmetric in tension and compression, with failure originating and propagating over a large range of tensile strains. PMID:21396601

  19. Status report of the single heater test chapter 4 integrated analyses

    SciTech Connect

    Lin, W., LLNL

    1998-02-26

    The primary purposes of the Single Heater Test (SHT) are to study the thermal-mechanical responses of the heated block. The SHT is too small and does not have adequate access for a complete study of the coupled thermal-hydrological-chemical processes. The SHT is used as a shake-down/scoping study for the thermal-hydrological- chemical processes. For the thermal-hydrological process, the temporal and spatial variations of the moisture content in the heated block are monitored by neutron logging in Holes 15, 17, 22, and 23, electrical resistivity tomograph (ERT) in Holes 24 to 27. In addition, relative humidity, gas pressure, and temperature are measured in zones between packers in Holes 16 and 18. Temperature is also measured by resistance temperature devices (RTD) in the neutron logging holes (1 5, 17, 22, and 23). Chemical sensors were installed in Holes 20 and 21, but the sensors did not respond to the moisture in the rock. Water was collected from Zone 4 in Hole l6. Calculated temperature distribution and the measured ones are compared. The humidity and gas pressure measurements in Holes 16 and 18 will are discussed. The moisture content measured by neutron logging and ERT will be presented and discussed. Calculated saturation distributions are presented and compared with the neutron logging results and the ERT. The chemical composition of the water collected from Hole 16 is discussed. Fracture closing and opening based on the thermomechanical measurements are summarized. Air permeability changes measured in Holes 16 and 18 are presented. An integrated discussion is presented.

  20. Intramuscular Single-dose Toxicity Test of Bufonis venonum Pharmacopuncture in Sprague-Dawley Rats

    PubMed Central

    Lee, Kwang-Ho; Sun, Seung-Ho; Yu, Jun-Sang; Kwon, Ki-Rok

    2015-01-01

    Objectives: Bufonis venonum (BV) is the dried white secretions of the auricular and skin glands of the toads Bufo bufo gargarizans or Bufo melanosticus Schneider. This study was performed to evaluate the toxicity of intramuscularly- administered Bufonis venonum pharmacopuncture (BVP) and to calculate its approximate lethality through a single-dose test with Sprague-Dawley (SD) rats. Methods: Twenty male and 20 female 6-week-old SD rats were injected intramuscularly with BVP or normal saline. The animals were divided into four groups with five female and five male rats per group: the control group injected with normal saline at 0.5 mL/animal, the low-dosage group injected with 0.125 mL/animal of BVP, the medium-dosage group injected with 0.25 mL/animal of BVP and the high-dosage group injected with 0.5 mL/animal of BVP. All injections were in the left thighs of the rats. After administration, we conducted clinical observations everyday and body weight measurements on days 3, 7 and 14 after the injection. We also carried out hematology, serum biochemistry, and histological observations on day 15 after treatment. Results: No mortalities were observed in any experimental group. No significant changes in weight, hematology, serum biochemistry, and histological observations that could be attributed to the intramuscular injection of BVP were observed in any experimental group. Conclusion: Lethal dose of BVP administered via intramuscular injection in SD rats is over 0.5 mL/animal. PMID:26998390

  1. PS II model-based simulations of single turnover flash-induced transients of fluorescence yield monitored within the time domain of 100 ns-10 s on dark-adapted Chlorella pyrenoidosa cells.

    PubMed

    Belyaeva, N E; Schmitt, F-J; Steffen, R; Paschenko, V Z; Riznichenko, G Yu; Chemeris, Yu K; Renger, G; Rubin, A B

    2008-01-01

    The set up described in Steffen et al. (Biochemistry 40:173-180, 2001) was used to monitor in the time domain from 100 ns to 10 s single turnover flash-induced transients of the normalized fluorescence yield (SFITFY) on dark-adapted cells of the thermophilic algae Chlorella pyrenoidosa Chick. Perfect data fit was achieved within the framework of a previously proposed model for the PS II reaction pattern (Lebedeva et al., Biophysics 47:968-980, 2002; Belyaeva et al., Biophysics 51:860-872, 2006) after its modification by taking into account nonradiative decay processes including nonphotochemical quenching due to time-dependent populations of P680(+*) and (3)Car. On the basis of data reported in the literature, a consistent set of rate constants was obtained for electron transfer at the donor and acceptor sides of PS II, pH in lumen and stroma, the initial redox state of plastoquinone pool and the rate of plastoquinone oxidation. The evaluation of the rate constant values of dissipative processes due to quenching by carotenoid triplets in antennae and P680(+*)Q(A)(-*) recombination as well as the initial state populations after excitation with a single laser flash are close to that outlined in (Steffen et al., Biochemistry 44:3123-3133, 2005a). The simulations based on the model of the PS II reaction pattern provide information on the time courses of population probabilities of different PS II states. We analyzed the maximum (F(m)(STF)) and minimum (F(0)) of the normalized FL yield dependence on the rate of the recombination processes (radiative and dissipative nonradiative) and of P680(+*) reduction. The developed PS II model provides a basis for theoretical comparative analyses of time-dependent fluorescence signals, observed at different photosynthetic samples under various conditions (e.g. presence of herbicides, other stress conditions, excitation with actinic pulses of different intensity, and duration). PMID:18937044

  2. Out-of-School Time Program Test Score Impact for Black Children of Single-Parents

    ERIC Educational Resources Information Center

    Nagle, Barry T.

    2013-01-01

    Out-of-School Time programs and their impact on standardized college entrance exam scores for black or African-American children of single parents who have applied for a competitive college scholarship program is the study focus. Study importance is supported by the large percentage of black children raised by single parents, the large percentage…

  3. Out-of-School Time Program Test Score Impact for Black Children of Single-Parents

    ERIC Educational Resources Information Center

    Nagle, Barry T.

    2013-01-01

    Out-of-School Time programs and their impact on standardized college entrance exam scores for black or African-American children of single parents who have applied for a competitive college scholarship program is the study focus. Study importance is supported by the large percentage of black children raised by single parents, the large percentage

  4. The Zwicky Transient Facility

    NASA Astrophysics Data System (ADS)

    Kulkarni, Shrinivas R.

    2016-01-01

    The Zwicky Transient Facility (ZTF) has been designed with a singular focus: a systematic exploration of the night sky at a magnitude level well suited for spectral classification and follow up with the existing class of 4-m to 10-m class telescopes. ZTF is the successor to the Palomar Transient Factory (PTF). The discovery engine for ZTF is a 47 square degree camera (realized through 16 e2V monolithic CCDs) that fills the entire focal plane of the 48-inch Oschin telescope of the Palomar Observatory. Single 30-s epoch sensitivity is about 20.5 in g and R bands. The Infarared Processing & Analysis Center (IPAC) is the data center for ZTF. ZTF is a public-private partnership with equal contributions from a consortium of world-wide partners and an NSF MSIP grant. Forty percent of ZTF time is set aside for two major community surveys: a 3-day cadence survey of high latitudes (to mimic LSST) and a time domain survey of the entire Northern Galactic plane. We expect first light in February 2017 and begin a 3-year survey starting summer of 2017. The first year will be spent on building up deep reference images of the sky (a must for transient surveys). During the second year IPAC will deliver near archival quality photometric products within 12 hours of observations. By comparison to reference images photometric alerts will be sent out. Year 3 will see the near real-time release of image differencing products. A Community Science Advisory Committee (CSAC), chaired by S. Ridgway (NOAO), has been set up to both advise the PI and to ensure that the US community's interests are well served. Astronomers interested in getting a head start on ZTF may wish to peruse the data releases from PTF. Young people (or young at heart) may wish to attend the annual summer school on PTF/ZTF (August, Caltech campus). The Principal Investigator (PI) for the project is S. Kulkarni and the Project Scientist is Eric Bellm.For further details please consult http://www.ptf.caltech.edu/ztf

  5. 100-liter transient transfection.

    PubMed

    Girard, Philippe; Derouazi, Madiha; Baumgartner, Gwendoline; Bourgeois, Michaela; Jordan, Martin; Jacko, Barbara; Wurm, Florian M

    2002-01-01

    This is the first report of two successful 100 l scale transienttransfections in a standard stirred bioreactor. More than half a gram of a monoclonal antibody (IgG) were produced in less than 10 days using a technology called large-scale transient gene expression(LS-TGE). Suspension adapted HEK 293 EBNA SF cells were transfectedwithin a 150 l (nominal) bioreactor by a modified calcium phosphateco-precipitation method with more than 75 mg of plasmid DNA per run.A mixture of three different plasmids, one encoding for the heavychain of a human recombinant immunoglobulin, the other for the corresponding light chain and a third one for the green fluorescent protein (GFP, 2-4% of DNA in transfection cocktail)were co-transfected. The GFP vector was chosen to monitor transfection efficiency. Expression of GFP could be registered asearly as 20 h after DNA addition, using fluorescence microscopy. We demonstrate that transient transfection can be done at the100 l scale, thus providing a new tool to produce hundreds of milligrams or even gram amounts of recombinant protein. Akey advantage of LS-TGE resides in its speed. In the presentedcases, the entire production process for the synthesis of halfa gram of a recombinant antibody, including DNA preparationand necessary expansion of cells prior to transfection, wasexecuted in less than a month. Having an established transfection/expression process allows to run productioncampaigns for any given protein, within one facility, with onesingle host cell line and therefore only one single seed train. Without any need to create and maintain stable cell lines, expression of new r-proteins is not only faster and more economical but also more flexible. PMID:19003082

  6. Emerging optocoupler issues with energetic particle-induced transients and permanent radiation degradation

    SciTech Connect

    Reed, R.A.; Barth, J.L.; LaBel, K.A.; Marshall, C.J.; D`Ordine, M.; Kim, H.S.

    1998-12-01

    Radiation-induced permanent degradation and single event transient effects for optocouplers are discussed in this paper. These two effects are independent to the first order and will be addressed separately. Displacement damage-induced degradation of optocoupler current transfer ratio is reviewed. New data are presented that show the importance of application specific testing and that generalized quantification of optocoupler CTR degradation can lead to incorrect predictions of actual circuit performance in a radiation environment. Data are given for various circuit loading and drive current parameters. Previous work that introduces the idea that two mechanisms exist for inducing transients on the optocoupler output is discussed. New data are presented that extends the evidence of this dual mechanism hypothesis. In this work measurements show that single event transient cross sections and transient propagation varies with circuit filtering. Finally, the authors discuss utilization of the optocouplers in the space environment. New data are applied to two examples: one on permanent degradation and the other on single event transient rates in high bandwidth applications.

  7. A single-well tracer test with in-situ-generated CO[sub 2] as the oil tracer

    SciTech Connect

    Wellington, S.L.; Richardson, E.A. )

    1994-05-01

    This paper documents a new single-well tracer chemistry that uses hydrolysis of halogen-organic acid salts as a means to generate CO[sub 2] and to trace residual-oil-saturation. The availability of generators with different, well-behaved hydrolysis rates allows the test to be tailored to each individual well. Suitable water tracers include methanol, tritium, bicarbonate, or the spent CO[sub 2] generator. Field results demonstrate test application and interpretation.

  8. Criticality of Low-Energy Protons in Single-Event Effects Testing of Highly-Scaled Technologies

    NASA Technical Reports Server (NTRS)

    Pellish, Jonathan A.; Marshall, Paul W.; Rodbell, Kenneth P.; Gordon, Michael S.; LaBel, Kenneth A.; Schwank, James R.; Dodds, Nathaniel A.; Castaneda, Carlos M.; Berg, Melanie D.; Kim, Hak S.; Phan, Anthony M.; Seidleck, Christina M.

    2014-01-01

    We report low-energy proton and low-energy alpha particle single-event effects (SEE) data on a 32 nm silicon-on-insulator (SOI) complementary metal oxide semiconductor (CMOS) latches and static random access memory (SRAM) that demonstrates the criticality of using low-energy protons for SEE testing of highly-scaled technologies. Low-energy protons produced a significantly higher fraction of multi-bit upsets relative to single-bit upsets when compared to similar alpha particle data. This difference highlights the importance of performing hardness assurance testing with protons that include energy distribution components below 2 megaelectron-volt. The importance of low-energy protons to system-level single-event performance is based on the technology under investigation as well as the target radiation environment.

  9. Testing a Poisson Counter Model for Visual Identification of Briefly Presented, Mutually Confusable Single Stimuli in Pure Accuracy Tasks

    ERIC Educational Resources Information Center

    Kyllingsbaek, Soren; Markussen, Bo; Bundesen, Claus

    2012-01-01

    The authors propose and test a simple model of the time course of visual identification of briefly presented, mutually confusable single stimuli in pure accuracy tasks. The model implies that during stimulus analysis, tentative categorizations that stimulus i belongs to category j are made at a constant Poisson rate, v(i, j). The analysis is

  10. 42 CFR 84.1145 - Silica dust test; non-powered single-use dust respirators; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Silica dust test; non-powered single-use dust respirators; minimum requirements. 84.1145 Section 84.1145 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Dust,...

  11. FUSION METHOD FOR THE MEASUREMENT OF PLUTONIUM IN SOILS: SINGLE-LABORATORY EVALUATION AND INTERLABORATORY COLLABORATIVE TEST

    EPA Science Inventory

    This report presents the results of a single-laboratory evaluation and an interlaboratory collaborative test of a method for measuring plutonium in soil. The method employs potassium fluoride and potassium pyrosulfate fusions to decompose a 10-gram sample, barium sulfate precipit...

  12. Functional Interrupts and Destructive Failures from Single Event Effect Testing of Point-Of-Load Devices

    NASA Technical Reports Server (NTRS)

    Chen, Dakai; Phan, Anthony; Kim, Hak; Swonger, James; Musil, Paul; LaBel, Kenneth

    2013-01-01

    We show examples of single event functional interrupt and destructive failure in modern POL devices. The increasing complexity and diversity of the design and process introduce hard SEE modes that are triggered by various mechanisms.

  13. Structurally responsive oligonucleotide-based single-probe lateral-flow test for detection of miRNA-21 mimics.

    PubMed

    Kor, Kamalodin; Turner, Anthony P F; Zarei, Kobra; Atabati, Morteza; Beni, Valerio; Mak, Wing Cheung

    2016-02-01

    A single-probe strip test for the rapid and sensitive detection of miRNA-21 mimics is reported herein. Highly specific structurally responsive bi-functional, thiol and biotin, DNA/LNA oligonucleotide probes (molecular beacons-MB) were designed and conjugated with gold nanoparticles (AuNPs) (i.e. biotin-MB-AuNPs). The proposed design had the ability to modulate the accessibility of the biotin group as a function of the presence of a miRNA target allowing the interaction of the boilable with the streptavidin test zone only in the presence of the miRNA-21 mimics. For quantitative evaluation, images of the strip tests were recorded using a flatbed scanner (Epson Perfection V370 Photo). The colour intensities of the test zones of the strip tests were analysed with the ImageJ software (Scion Corp., USA) and quantified as a function of pixel intensity. The response of the strip test was linear over the range 0.5 to 20 nM miRNA-21 (limit of detection of 115 pM) and showed good reproducibility (intra and inter CVs below 8 %); furthermore, the assay was shown to be highly selective, discriminating other interference miRNAs mimics (e.g. miRNA-221 and miRNA-205). Finally, the proposed strip test was used for detection of miRNA-21 mimics in spiked serum samples, demonstrating its potential for point-of-care clinical applications. Main advantages of the single-probe strip test design are its versatility, simplicity and robustness, which can be easily extended to other miRNA targets by tuning the sequence of the single probe. Furthermore, the use of the structurally responsive single probe is particularly relevant in the case of short-length targets, such as miRNA, whereas a conventional sandwich approach might require a careful control of assay conditions such as hybridization temperature and salt concentration. Graphical Abstract Pictorial representation of the working principle of the proposed structurally responsive oligonucleotide-based single-probe lateral-flow test and example of the test response as a function of increasing concentration of target analyte. PMID:26700447

  14. Assessment of the sensitivity of the gamma-interferon test and the single intradermal comparative cervical test for the diagnosis of bovine tuberculosis under field conditions.

    PubMed

    Praud, A; Boschiroli, M L; Meyer, L; Garin-Bastuji, B; Dufour, B

    2015-01-01

    In some French départements, the eradication of bovine tuberculosis is incomplete and usual skin tests [single intradermal tuberculin test (SIT) and single intradermal comparative cervical test (SICCT)] have poor specificity due to cross-reactions with non-pathogenic mycobacteria, causing economic losses. In Côte d'Or (Burgundy, France), an experimental serial testing scheme based on the combination of SICCT and gamma-interferon (IFN-γ) tests has been initiated in order to shorten the interval between suspicion and its invalidation in herds with false-positive results to skin tests. Our aim was to assess the scheme's sensitivity and to compare it to the sensitivity of the screening scheme recommended by the European Commission. Our study included 1768 animals from Côte d'Or. The sensitivities of both schemes were estimated using a Bayesian approach. The individual sensitivity of the IFN-γ test [88·1%, 95% credibility interval (CrI) 72·8-97·5] was not significantly different from individual SICCT sensitivity (80·3%, 95% CrI 61·6-98·0) and individual SIT sensitivity (84·2%, 95% CrI 59·0-98·2). The individual specificity of the IFN-γ test was 62·3% (95% CrI 60·2-64·5). No significant difference could be demonstrated between the sensitivities of the serial testing scheme used in Côte d'Or (73·1%, 95% CrI 41·1-100) and the European Union serial testing scheme (70·1%, 95% CrI 31·5-100·0). PMID:24576504

  15. Flow tests of a single fuel element coolant channel for a compact fast reactor for space power

    NASA Technical Reports Server (NTRS)

    Springborn, R. H.

    1971-01-01

    Water flow tests were conducted on a single-fuel-element cooling channel for a nuclear concept to be used for space power. The tests established a method for measuring coolant flow rate which is applicable to water flow testing of a complete mockup of the reference reactor. The inlet plenum-to-outlet plenum pressure drop, which approximates the overall core pressure drop, was measured and correlated with flow rate. This information can be used for reactor coolant flow and heat transfer calculations. An analytical study of the flow characteristics was also conducted.

  16. Fabrication and Testing of Full-Length Single-Cell Externally Fueled Converters for Thermionic Reactors

    SciTech Connect

    Schock, Alfred

    1995-08-01

    Paper presented at the 29th IECEC in Monterey, CA in August 1994. The present paper describes the fabrication and testing of full-length prototypcial converters, both unfueled and fueled, and presents parametric results of electrically heated tests.

  17. Discrete element simulations and validation tests investigating solids-conveying processes with pressure buildup in single screw extruders

    NASA Astrophysics Data System (ADS)

    Lessmann, Johann-Sebastian; Schoeppner, Volker

    2016-03-01

    The goal of this contribution is to describe a method of simulating solids-conveying processes in single screw extruders which include a defined back pressure leading to a resulting pressure buildup in the screw channel. To do so, use is made of the Discrete Element Method. Material parameters are presented, as well as details concerning the contact model used and the simulation tool EDEM. Additionally, a test setup is presented which has been used to validate the solids-conveying simulations. Results are shown for both simulations and experimental tests. Comparing the results from simulations and measurements shows acceptable conformity. Such simulations and experimental tests are crucial in order to better understand the buildup of pressure in high-speed single-screw extruders.

  18. Single Group, Pre- and Post-Test Research Designs: Some Methodological Concerns

    ERIC Educational Resources Information Center

    Marsden, Emma; Torgerson, Carole J.

    2012-01-01

    This article provides two illustrations of some of the factors that can influence findings from pre- and post-test research designs in evaluation studies, including regression to the mean (RTM), maturation, history and test effects. The first illustration involves a re-analysis of data from a study by Marsden (2004), in which pre-test scores are

  19. Single Group, Pre- and Post-Test Research Designs: Some Methodological Concerns

    ERIC Educational Resources Information Center

    Marsden, Emma; Torgerson, Carole J.

    2012-01-01

    This article provides two illustrations of some of the factors that can influence findings from pre- and post-test research designs in evaluation studies, including regression to the mean (RTM), maturation, history and test effects. The first illustration involves a re-analysis of data from a study by Marsden (2004), in which pre-test scores are…

  20. A Methodology to Hydraulically Parameterize Deformation Zones and Fracture Networks in Fractured Crystalline Rock Using Fracture Borehole Data and Inflow Data from Single- Hole Tests

    NASA Astrophysics Data System (ADS)

    Follin, S.; Hartley, L.; Rhen, I.; Selroos, J.

    2008-12-01

    Three-dimensional, regional, numerical models of groundwater flow and solute transport in fractured crystalline rock are used for two sites in Sweden that are considered for geological disposal of spent nuclear fuel. The models are used to underpin the conceptual modeling that is based on multi-disciplinary data and include descriptions of the geometry of geological features (deformation zones and fracture networks), transient hydrological and chemical boundary conditions, strong spatial heterogeneity in the hydraulic properties, density driven flow, solute transport including rock matrix diffusion, and mixing of different water types in a palaeo-hydrogeological perspective (last 10,000 years). The general approach applied in the numerical modeling was to first parameterize the deformation zones and fracture networks hydraulically using fracture and inflow data from single-hole tests. Second, a confirmatory step was attempted using essentially the same groundwater flow and solute transport model in terms of grid discretization and parameter settings for matching three types of independent field data: 1) large-scale cross-hole (interference) tests, 2) long- term monitoring of groundwater levels, and 3) hydrochemical composition of fracture water and matrix pore water in deep boreholes. We demonstrate here the adopted modelling approach for the first step, i.e. hydraulic parameterization of deformation zones and fracture networks, using single-hole test data from the site investigations undertaken at one of the sites in Sweden (Forsmark). The adopted modelling approach combines a deterministic representation of the major deformation zones with a stochastic representation of the less fractured bedrock outside these zones using the discrete fracture network (DFN) concept. An exponential model for the depth dependency of the in-plane deformation zone transmissivity was suggested based on the data. Lateral heterogeneity was simulated by adding a log-normal random deviate. A tectonic continuum is envisaged for the DFN concept where the number (intensity) of fractures of different sizes follows a power-law relationship. The methodology used to parameterise the discrete fracture networks starts with a connectivity-sensitivity analysis of different DFN models and ends with flow simulations using the most reliable DFN model deduced in the connectivity analysis. The flow simulations were carried out using three different kinds of correlations between fracture transmissivity and fracture size. For each correlation model, the model parameters were changed in a forward manner until a reasonable match against measured specific capacities (Q/?p) was achieved.

  1. Transient Voltage Recorder

    NASA Astrophysics Data System (ADS)

    Medelius, Pedro J.; Simpson, Howard J.

    2002-09-01

    A voltage transient recorder can detect lightning induced transient voltages. The recorder detects a lightning induced transient voltage and adjusts input amplifiers to accurately record transient voltage magnitudes. The recorder stores voltage data from numerous monitored channels, or devices. The data is time stamped and can be output in real time, or stored for later retrieval. The transient recorder, in one embodiment, includes an analog-to-digital converter and a voltage threshold detector. When an input voltage exceeds a pre-determined voltage threshold, the recorder stores the incoming voltage magnitude and time of arrival. The recorder also determines if its input amplifier circuits clip the incoming signal or if the incoming signal is too low. If the input data is clipped or too low, the recorder adjusts the gain of the amplifier circuits to accurately acquire subsequent components of the lightning induced transients.

  2. The anomaly in a breakthrough curve of a single well "push-pull" tracer test: A density driven effect?

    NASA Astrophysics Data System (ADS)

    Zeilfelder, Sarah; Hebig, Klaus; Ito, Narimitsu; Machida, Isao; Scheytt, Traugott; Marui, Atsunao

    2013-04-01

    What method is appropriate to investigate an aquifer when there is only one well available? A single well "push-pull" tracer test (PP Test) may be a suitable method in order to characterize an aquifer and to obtain information about the hydraulic and chemical properties when only one well is available for the investigations. In a PP test, a test solution that contains a known amount of solutes and a conservative tracer is injected into the aquifer ("push") and extracted afterwards ("pull"). Optionally, the test solution is flushed out of the well and the casing with untreated test solution with a so called "chaser" before being extracted. Also between the injection and the extraction phase a drifting time may be included. The breakthrough of the tracer during the extraction phase is measured and used for analyses and interpretation. In the last three years, several PP Test campaigns were conducted at two different test sites in Japan (Hebig et al. 2011, Zeilfelder et al. 2012). The aim was to investigate the applicability of the PP Test method in different geological settings and in different types of aquifers. The latest field campaign thus focussed on the question how variations of the setup are influencing the breakthrough curve of the PP Test in order to develop and enhance this method. Also the standardization of the PP Test was an aim of this study. During the campaign, a total of seven PP Tests were performed, while only single aspects of the setup were varied from test to test. The tests differed in injection and extraction rate, in the salinity of the injected test solution and in the use of a chaser solution. The general shapes of the breakthrough curves were similar and conclusions about the repeatability of the PP Test could be drawn. However, a sharp anomaly was observed in the breakthrough curve of one specific setup type. By repeating this PP test under the same boundary conditions, we were able to recreate the anomaly and could exclude any technical aspects as a source. In this version of the PP test higher salinized test solution was injected into the aquifer. There are several hypotheses that could explain the behavior of the breakthrough curves of the tracer in this test design. Of all the possibilities (like sorption processes, unexpected tracer reactions, inhomogeneities in the aquifer, influence of the well design), we assume that ion exchange processes and density driven flow are the main reasons for the repeatedly observed anomaly. References: Hebig, K.H., Ito, N., Scheytt, T.J. & Marui, A. (2011). Hydraulic and hydrochemical characterization of deep coastal sedimentary basins by single-well Push-Pull tests. GSA Annual Meeting, 9-12 October 2011, Minneapolis, USA. Zeilfelder, S., Ito, N., Marui, A., Hebig, K. & Scheytt, T. (2012). Push-Pull-Test und Tracer-Test in einem tiefen Grundwasserleiter in Kameoka, Japan. Kurzfassung in: Liedl, R., Burghardt, D., Simon, E., Reimann, T. & Kaufmann-Knoke (Hg.). Grundwasserschutz und Grundwassernutzung. Tagung der Fachsektion Hydrogeologie in der DGG (FH-DGG). 16. - 20. Mai 2012, Dresden. Kurfassungen der Vorträge und Poster. Schriftenreihe der DGG, Heft 78, S. 192.

  3. Testing Single Phase IGBT H-Bridge Switch Plates for the High Voltage Converter Modulator at the Spallation Neutron Source

    SciTech Connect

    Peplov, Vladimir V; Anderson, David E; Solley, Dennis J

    2014-01-01

    Three IGBT H-bridge switching networks are used in each High Voltage Converter Modulator (HVCM) system at the Spallation Neutron Source (SNS) to generate drive currents to three boost transformer primaries switching between positive and negative bus voltages at 20 kHz. Every switch plate assembly is tested before installing it into an operational HVCM. A Single Phase Test Stand has been built for this purpose, and it is used for adjustment, measurement and testing of different configurations of switch plates. This paper will present a description of the Test Stand configuration and discuss the results of testing switch plates with two different types of IGBT gate drivers currently in use on the HVCM systems. Comparison of timing characteristics of the original and new drivers and the resulting performance reinforces the necessity to replace the original H-bridge network drivers with the upgraded units.

  4. Ground Vibration and Flight Flutter Tests of the Single-seat F-16XL Aircraft with a Modified Wing

    NASA Technical Reports Server (NTRS)

    Voracek, David F.

    1993-01-01

    The NASA single-seat F-16XL aircraft was modified by the addition of a glove to the left wing. Vibration tests were conducted on the ground to assess the changes to the aircraft caused by the glove. Flight Luther testing was conducted on the aircraft with the glove installed to ensure that the flight envelope was free of aeroelastic or aeroservoelastic instabilities. The ground vibration tests showed that above 20 Hz, several modes that involved the control surfaces were significantly changed. Flight test data showed that modal damping levels and trends were satisfactory where obtainable. The data presented in this report include estimated modal parameters from the ground vibration and flight flutter test.

  5. Evaluation of the single-pass flow-through test to support a low-activity waste specification

    SciTech Connect

    McGrail, B.P.; Peeler, D.K.

    1995-09-01

    A series of single-pass flow-through (SPFT) tests was performed on five reference low-activity waste glasses and a reference glass from the National Institute of Standards and Technology to support a product specification for low-activity waste (LAW) forms. The results showed that the SPFT test provides a means to quantitatively distinguish among LAW glass forms in terms of their forward reaction rate at a given temperature and solution pH. Two of the test glasses were also subjected to SPFT testing at Argonne National Laboratory (ANL). Forward reaction rate constants calculated from the ANL test data were 100 to over 1,000 times larger than the values obtained from the SPFT tests conducted at PNL. An analysis of the ANL results showed that they were inconsistent with independent measurements done on glasses of similar composition, the known pH-dependence of the forward rate, and with the results from low surface-area-to-volume, short duration product consistency tests. Because the data set obtained from the SPFT tests done at PNL was consistent with each of these same factors, a detailed examination of the test procedures used at both laboratories was performed to determine the cause(s) of the discrepancy. The omission of background subtraction in the data analysis procedure and the short-duration (on the order of hours) of the ANL tests are factors that may have significantly affected the calculated rates.

  6. Prediction of single versus multivessel disease following myocardial infarction using 201-thallium scintigraphy and electrocardiographic stress testing

    SciTech Connect

    Weiss, R.J.; Morise, A.P.; Raabe, D.S. Jr.; Sbarbaro, J.A.

    1983-11-01

    Fifty patients were evaluated who suffered a single myocardial infarction with graded electrocardiographic stress testing, 201-thallium myocardial perfusion imaging and coronary angiography to assess the role of noninvasive indices as predictors of single versus multivessel coronary artery disease. Multivessel involvement was defined angiographically as the presence of two or more major coronary arteries with at least a 70% intraluminal diameter narrowing. Multivessel disease was defined scintigraphically as the presence of stress and/or redistribution perfusion defects in the distribution of more than one coronary artery. The results of stress electrocardiography were not useful in differentiating patients with single (9/16 positive) versus multivessel (22/34 positive) disease. The degree of exercise-induced ST-segment depression was also not helpful. Stress 201-thallium imaging did offer limited additional information with correct predictions of multivessel disease in 21 of 26 patients. Predictions of single-vessel disease were accurate in 11 of 24 patients. Eleven of these 13 incorrect predictions of single-vessel disease were due to the relative insensitivity of the thallium stress image to perceive defect in the anterior wall when the left anterior descending artery had significant obstruction at catheterization. Further refinements of stress perfusion imaging are needed before this method can be used to reliably separate patients with single and multivessel disease after myocardial infarction.

  7. Detection of false transients

    NASA Astrophysics Data System (ADS)

    Galleani, Lorenzo; Cohen, Leon; Nelson, Douglas J.

    2005-08-01

    When one calculates a time-frequency distribution of white noise there sometimes appear transients of short duration. Superficially, these transients appear to be real signals but they are not. This comes about by random chance in the noise and also because particular types of distributions do not resolve components well in time. These fictitious signals can be misclassified by detectors and hence it is important to understand their origin and statistical properties. We present experimental studies regarding these false transients, and by simulation we statistically quantify their duration for various distributions. We compare the number and duration of the false transients when different distributions are used.

  8. The Mechanical Transient Process at Asynchronous Motor Oscillating Mode

    NASA Astrophysics Data System (ADS)

    Antonovičs, Uldis; Bražis, Viesturs; Greivulis, Jānis

    2009-01-01

    The research object is squirrel-cage asynchronous motor connected to single-phase sinusoidal. There are shown, that by connecting to the stator windings a certain sequence of half-period positive and negative voltage, a motor rotor is rotated, but three times slower than in the three-phase mode. Changing the connecting sequence of positive and negative half-period voltage to stator windings, motor can work in various oscillating modes. It is tested experimentally. The mechanical transient processes had been researched in rotation and oscillating modes.

  9. Subchronic toxicity test for two thermotolerant filamentous fungi used for single cell protein production.

    PubMed Central

    Kuo, C Y; Alexander, J C; Lumsden, J H; Thomson, R G

    1979-01-01

    Safety evaluations of two thermotolerant filamentous fungi, Cephalosporium eichhorniae 152 (C. 152) and Rhizopus chinensis 180 (R. 180), grown on a sugar-salts medium were carried out through feeding the biomases to rats at 20% or 40% dietary levels for 90 days. There was a control group fed soybean meal. Weight gain and feed consumption for rats fed 20% C. 152 were equal to those for the control animals, but were depressed in the other three groups, especially the rats fed R. 180. All animals appeared normal and healthy except that transient alopecia was found for a short duration in the fungi-treated rats in the initial period. The cause of this lesion is not clear. At the end of the feeding trial, clinical determinations of constituents in blood and urine samples were conducted. The animals were autopsied and weights for four organs were taken. Histopathological examinations for 26 different tissues were carried out. Mild changes were found in both C. 152 and R. 180-treated rats but most of the these were not considered to be related to treatment. PMID:570875

  10. Building a Robust Tumor Profiling Program: Synergy between Next-Generation Sequencing and Targeted Single-Gene Testing

    PubMed Central

    Lieberman, David B.; Roth, David B.; Zhao, Jianhua; Watt, Christopher D.; Daber, Robert D.; Morrissette, Jennifer J. D.

    2016-01-01

    Next-generation sequencing (NGS) is a powerful platform for identifying cancer mutations. Routine clinical adoption of NGS requires optimized quality control metrics to ensure accurate results. To assess the robustness of our clinical NGS pipeline, we analyzed the results of 304 solid tumor and hematologic malignancy specimens tested simultaneously by NGS and one or more targeted single-gene tests (EGFR, KRAS, BRAF, NPM1, FLT3, and JAK2). For samples that passed our validated tumor percentage and DNA quality and quantity thresholds, there was perfect concordance between NGS and targeted single-gene tests with the exception of two FLT3 internal tandem duplications that fell below the stringent pre-established reporting threshold but were readily detected by manual inspection. In addition, NGS identified clinically significant mutations not covered by single-gene tests. These findings confirm NGS as a reliable platform for routine clinical use when appropriate quality control metrics, such as tumor percentage and DNA quality cutoffs, are in place. Based on our findings, we suggest a simple workflow that should facilitate adoption of clinical oncologic NGS services at other institutions. PMID:27043212

  11. Assessing and Testing Interrater Agreement on a Single Target Using Multi-Item Rating Scales.

    ERIC Educational Resources Information Center

    Lindell, Michael K.

    2001-01-01

    Developed an index for assessing interrater agreement with respect to a single target using a multi-item rating scale. The variance of rater mean scale scores is used as the numerator of the agreement index. Studied four variants of a disattenuated agreement index that vary in the random response term used as the denominator. (SLD)

  12. Single cells for forensic DNA analysis--from evidence material to test tube.

    PubMed

    Brück, Simon; Evers, Heidrun; Heidorn, Frank; Müller, Ute; Kilper, Roland; Verhoff, Marcel A

    2011-01-01

    The purpose of this project was to develop a method that, while providing morphological quality control, allows single cells to be obtained from the surfaces of various evidence materials and be made available for DNA analysis in cases where only small amounts of cell material are present or where only mixed traces are found. With the SteREO Lumar.V12 stereomicroscope and UV unit from Zeiss, it was possible to detect and assess single epithelial cells on the surfaces of various objects (e.g., glass, plastic, metal). A digitally operated micromanipulator developed by aura optik was used to lift a single cell from the surface of evidence material and to transfer it to a conventional PCR tube or to an AmpliGrid(®) from Advalytix. The actual lifting of the cells was performed with microglobes that acted as carriers. The microglobes were held with microtweezers and were transferred to the DNA analysis receptacles along with the adhering cells. In a next step, the PCR can be carried out in this receptacle without removing the microglobe. Our method allows a single cell to be isolated directly from evidence material and be made available for forensic DNA analysis. PMID:21198592

  13. Race, Gender, Single-Mother Households, and Delinquency: A Further Test of Power-Control Theory

    ERIC Educational Resources Information Center

    Mack, Kristin Y.; Leiber, Michael J.

    2005-01-01

    Using power-control theory as the theoretical framework, the present study examines the gender gap in delinquency for White and African American youth from single-mother households. The research is driven by the need to focus more attention on understanding how delinquency theories apply across different racial groups. Results from both bivariate

  14. Gamma Ray Transients

    NASA Astrophysics Data System (ADS)

    Gehrels, N.

    Almost every source in the gamma-ray sky is variable. Transient classification therefore depends on the definition of ``transient'' and on instrument sensitivity thresholds. The sources that most clearly fall in the transient category are those that have large intensity differences between their low (or off) states and their high states and have well defined high states with durations less than about a year. Examples are gamma-ray bursts, solar flares, X-ray novae, jet transients, bursting pulsars and Be binary pulsars. Generally, most accreting neutron stars, galactic black holes and AGN are variable with periods of high intensity that can be labeled as transient outbursts. Supernovae and novae form another class of gamma-ray transient driven by explosive nucleosynthesis. The Compton Gamma Ray Observatory (CGRO) has been observing the gamma-ray sky for 6 years. Many of the scientific discoveries from the mission have related to transient observations. The BATSE instrument onboard is a powerful all-sky monitor with 50 m Crab detection sensitivity above 20 keV. The OSSE instrument has a narrow field-of-view with limited sky coverage, but has excellent sensitivities above 50 keV for specific objects. At higher MeV and GeV energies the COMPTEL and EGRET instruments have wide fields-of-view that give reasonable coverage of the sky. In this talk I will review the different classes of gamma-ray transient and present results from CGRO observations.

  15. Perception of acoustic transients

    NASA Astrophysics Data System (ADS)

    Howard, J. H., Jr.

    1984-01-01

    The research investigates the role of knowledge based or top-down processing in the perception of nonlinguistic, transient signals. The experiments address issues in transient pattern classification, target observation, attentional focusing, auditory induction, and computer based performance aids. The theoretical significance and naval relevance of the research is considered.

  16. Comparison of modal test results - Multipoint sine versus single-point random. [for Mariner Jupiter/Saturn spacecraft

    NASA Technical Reports Server (NTRS)

    Leppert, E. L.; Lee, S. H.; Day, F. D.; Chapman, P. C.; Wada, B. K.

    1976-01-01

    The Mariner Jupiter/Saturn (MJS) spacecraft was subjected to the traditional multipoint sine dwell (MPSD) modal test using 111 accelerometer channels, and also to single-point random (SPR) testing using 26 accelerometer channels, and the two methods are compared according to cost, schedule, and technical criteria. A measure of comparison between the systems was devised in terms of the cumulative difference in the kinetic energy distribution of the common accelerometers. The SPR and MPSD method show acceptable agreement with respect to frequencies and mode damping. The merit of the SPR method is that the excitation points are minimized and the test article can be committed to other uses while data analysis is performed. The MPSD approach allows validity of the data to be determined as the test progresses. Costs are about the same for the two methods.

  17. Experiment MA-028 crystal growth. [low gravity manufacturing of single crystals from Apollo/Soyuz Test Project

    NASA Technical Reports Server (NTRS)

    Lind, D. M.

    1976-01-01

    A crystal growth experiment is reported on orbital space flights. The experiment was performed during the Apollo-Soyuz Test Project. The Crystal Growth Experiment assessed a novel process for growing single crystals of insoluble substances by allowing two or more reactant solutions to diffuse toward each other through a region of pure solvent in zero gravity. The experiment was entirely successful and yielded crystals of about the expected size, quality, and number.

  18. Structural changes and damage of single-crystal turbine blades during life tests of an aviation gas turbine engine

    NASA Astrophysics Data System (ADS)

    Ospennikova, O. G.; Orlov, M. R.; Kolodochkina, V. G.; Nazarkin, R. M.

    2015-04-01

    The irreversible structural changes of the single-crystal ZhS32-VI nickel superalloy blades of a high-pressure turbine that occur during life tests of a gas turbine engine are studied. The main operation damages in the hottest section of the blade airfoil are found to be the fracture of the heat-resistant coating in the leading edge and the formation of thermomechanical fatigue cracks. The possibility of reconditioning repair of the blades is considered.

  19. Using energy balances for processing the results from tests of a single-shaft combined-cycle power plant

    NASA Astrophysics Data System (ADS)

    Ol'khovskii, G. G.

    2012-09-01

    Application of the balance method for dividing the overall power output produced by a single-shaft combined-cycle power plant between the steam turbine and gas turbine unit is considered. It is shown that the method can be used for obtaining trustworthy results of thermal tests. The effect of air flowrate taken for gas turbine cooling purposes on the gas turbine unit parameters and indicators is estimated.

  20. Prevalence of Bacterial Contamination of Glucose Test Strips in Individual Single-Use Packets versus Multi-Use Vials

    PubMed Central

    Pérez-Ayala, Millán; Oliver, Paloma; Cantalejo, Fernando Rodríguez

    2013-01-01

    Background: Glucose measurement is the cornerstone of diabetes control. In the hospital setting, the same device and package of test strips (50 or 100 strips) can be used to monitor glucose in several patients, which can increase cross contamination. The objective of our study is to measure bacterial contamination in glucose test strips, comparing results in individual single-use packets (one hospital) versus multi-use vials (two hospitals) in Spain. Methods: Test strips were collected from five different wards. Each hospital also collected two unopened vials from a single ward as controls. They were sent to a reference laboratory for microbiologic study. A number equal or higher than two colony forming units per strip was considered as a positive result. Results: Out of 423 glucose test strips collected and cultured, 146 were contaminated (34%); only 7% of individually packed strips were contaminated versus 45% of strips packed in multi-use vials, with a high statistical significance (p < .001). Conclusions: In the strips from multi-use vials, a high contamination rate was found and highly pathogenic organisms were identified, such as methicillin-resistant Staphylococcus epidermidis or Staphylococcus hemolyticus. In contrast, in strips packed individually, there was a much lower contamination rate and no such pathogen organisms were found. Therefore, in the hospital setting, the use of blood glucose test strips in individual packages would be more advantageous (mainly from a clinical point of view, but also from a financial one) than those packed in multiuse vials. PMID:23911166