Sample records for slsf experiment p4

  1. Fuel canister and blockage pin fabrication for SLSF Experiment P4. [LMFBR

    Microsoft Academic Search

    H. V. Rhude; J. R. Folkrod; R. A. Noland; P. S. Schaus; M. W. Benecke; T. A. Delucchi

    1983-01-01

    As part of its fast breeder reactor safety research program, Argonne National Laboratory (ANL) has conducted an experiment (SLSF Experiment P4) to determine the extent of fuel-failure propagation resulting from the release of molten fuel from one or more heat-generating fuel canisters. The test conditions consisted of 37 full-length FTR fuel pins operating at FTR rated core nominal peak fuel\\/reduced

  2. SLSF local fault safety experiment P4: summary and conclusions. [Sodium Loop Safety Facility

    SciTech Connect

    Thompson, D.H.; Ragland, W.A.; Holland, J.W.; Dever, D.J.; Braid, T.H.; Baldwin, R.D.; Anderson, T.T.

    1985-01-01

    Sodium Loop Safety Facility (SLSF) experiment P4 in ETR was performed to investigate the consequences of an upper-bound or worse-than-worst case local fault configuration. P4 was intended to bound the consequences of credible subassembly faults by ejecting molten fuel into a 37-pin bundle of full-length Fast Test Reactor (FTR)-type pins and failing fuel with the potential for further cladding and fuel-pin damage. In addition to ejecting a large amount of molten fuel at or near full power, experiment objectives were to evaluate the severity of molten fuel-coolant interactions (MFCIs) and to demonstrate that any resulting blockage could either be tolerated during continued power operation or detected by global monitors in time to prevent significant fuel failure propagation.

  3. HEDL W-1 SLSF experiment LOPI transient and boiling test results. [LMFBR

    Microsoft Academic Search

    J. M. Henderson; S. A. Wood; R. B. Rothrock

    1980-01-01

    The W-1 Sodium Loop Safety Facility (SLSF) experiment was designed to study the heat release characteristics of fast reactor fuel pins under Loss-of-Piping-Integrity (LOPI) accident conditions and determine stable sodium boiling initiation and recovery limits in a prototypic fuel pin bundle array. The results of the experiment address major second level of assurance (LOA-2) safety issues and provide increased insight

  4. Characterizing W-2 SLSF experiment temperature oscillations using computer graphics. [Sodium Loop Safety Facility

    SciTech Connect

    Smith, D.E.

    1983-06-23

    The W-2 SLSF (Sodium Loop Safety Facility) experiment was an instrumented in-reactor test performed to characterize the failure response of full-length, preconditioned LMFBR prototypic fuel pins to slow transient overpower (TOP) conditions. Although the test results were expected to confirm analytical predictions of upper level failure and fuel expulsion, an axial midplane failure was experienced. Extensive post-test analyses were conducted to understand all of the unexpected behavior in the experiment. (1) The initial post-test effort focused on the temperature oscillations recorded by the 54 thermocouples used in the experiment. In order to synthesize the extensive data records and identify patterns of behavior in the data records, a computer-generated film was used to present the temperature data recorded during the experiment.

  5. GE post-test analysis of SLSF experiment W-1 through LOPI-4. [LMFBR

    SciTech Connect

    Gregoire, K.E.; Atcheson, D.B.; Knight, D.D.

    1981-07-01

    SLSF experiment W-1 was designed to investigate fuel pin-to-coolant heat transfer during various LMFBR flow-coastdown events in the burnup interval from 0.0 atom percent to 0.5 atom percent. In the study reported here, data from in-fuel thermocouples and coolant (wire-wrap) thermocouples were evaluated during steady-state and transient operation from the beginning of the experiment through LOPI-4 (Loss-of-Piping-Integrity Transient Number 4). The objective of the data evaluation was to determine how maximum coolant temperatures during successive LOPI transients were affected by burnup. A second objective was to identify the mechanisms responsible for this burnup effect.

  6. Sodium Loop Safety Facility W-2 experiment fuel pin rupture detection system. [LMFBR

    Microsoft Academic Search

    M. A. Hoffman; T. L. Kirchner; S. C. Meyers

    1980-01-01

    The objective of the Sodium Loop Safety Facility (SLSF) W-2 experiment is to characterize the combined effects of a preconditioned full-length fuel column and slow transient overpower (TOP) conditions on breeder reactor (BR) fuel pin cladding failures. The W-2 experiment will meet this objective by providing data in two technological areas: (1) time and location of cladding failure, and (2)

  7. W-1 Sodium Loop Safety Facility experiment centerline fuel thermocouple performance. [LMFBR

    SciTech Connect

    Meyers, S.C.; Henderson, J.M.

    1980-05-01

    The W-1 Sodium Loop Safety Facility (SLSF) experiment is the fifth in a series of experiments sponsored by the Department of Energy (DOE) as part of the National Fast Breeder Reactor (FBR) Safety Assurance Program. The experiments are being conducted under the direction of Argonne National Laboratory (ANL) and Hanford Engineering Development Laboratory (HEDL). The irradiation phase of the W-1 SLSF experiment was conducted between May 27 and July 20, 1979, and terminated with incipient fuel pin cladding failure during the final boiling transient. Experimental hardware and facility performed as designed, allowing completion of all planned tests and test objectives. This paper focuses on high temperature in-fuel thermocouples and discusses their development, fabrication, and performance in the W-1 experiment.

  8. W-1 SLSF post-test data analysis. Part 1. Thermal hydraulic analysis. [LMFBR

    SciTech Connect

    Knight, D.D.

    1980-10-01

    Four types of tests were performed: (1) a decay heat transient test, (2) Loss-of-Piping-Integrity (LOPI) tests, (3) Boiling Window Tests (BWT), and (4) a fuel pin dryout and failure test. In addition, preliminary tests were run to check systems performance, instrumentation performance and test section heat balance. The objective of the decay heat test was to determine the decay heat transfer characteristics of fresh fuel pins with subcooled sodium. The objective of the LOPI experiments was to test the thermal behavior of fuel pins with four different fuel conditions subjected to the same transient. The transient was designed to simulate a rapid flow decrease as a result of pipe rupture followed by a reactor scram. The objective of the Boiling Window Tests was to study boiling initiation and progression of boiling within the fuel pin bundle.

  9. P4P4P: An Agenda for Research on Pay for Performance for Patients

    PubMed Central

    Volpp, Kevin G.; Pauly, Mark V.; Loewenstein, George; Bangsberg, David

    2012-01-01

    Unhealthy behaviors are a major cause of poor health outcomes and high health care costs. In this Commentary, we describe an agenda for research to guide broader use of patient-targeted financial incentives either in conjunction with provider-targeted financial incentives (P4P) or in clinical contexts where provider-targeted approaches are unlikely to be effective. We discuss evidence of proven effectiveness and limitations of the existing evidence, reasons for underutilization of these approaches, and options for operationalizing wider use. Patient-targeted incentives have great potential, and systematic testing will help determine how they can best be used to improve population health. PMID:19124872

  10. Preparative parallel protein purification (P4).

    PubMed

    Strömberg, Patrik; Rotticci-Mulder, Joke; Björnestedt, Robert; Schmidt, Stefan R

    2005-04-15

    In state of the art drug discovery, it is essential to gain structural information of pharmacologically relevant proteins. Increasing the output of novel protein structures requires improved preparative methods for high throughput (HT) protein purification. Currently, most HT platforms are limited to small-scale and available technology for increasing throughput at larger scales is scarce. We have adapted a 10-channel parallel flash chromatography system for protein purification applications. The system enables us to perform 10 different purifications in parallel with individual gradients and UV monitoring. Typical protein purification applications were set up. Methods for ion exchange chromatography were developed for different sample proteins and columns. Affinity chromatography was optimized for His-tagged proteins using metal chelating media and buffer exchange by gel filtration was also tested. The results from the present system were comparable, with respect to resolution and reproducibility, with those from control experiments on an AKTA purifier system. Finally, lysates from 10 E. coli cultures expressing different His-tagged proteins were subjected to a three-step parallel purification procedure, combining the above-mentioned procedures. Nine proteins were successfully purified whereas one failed probably due to lack of expression. PMID:15722038

  11. Syzygies of Abelian and Bielliptic Surfaces in P^4

    Microsoft Academic Search

    Alf Aure; Wolfram Decker; Klaus Hulek; Sorin Popescu; Kristian Ranestad

    1996-01-01

    So far only six families of smooth irregular surfaces are known to exist in P^4 (up to pullbacks by suitable finite covers of P^4). These are the elliptic quintic scrolls, the minimal abelian and bielliptic surfaces (of degree 10), two different families of non-minimal abelian surfaces of degree 15, and one family of non-minimal bielliptic surfaces of degree 15. The

  12. Sodium Loop Safety Facility W-2 experiment fuel pin rupture detection system. [LMFBR

    SciTech Connect

    Hoffman, M.A.; Kirchner, T.L.; Meyers, S.C.

    1980-05-01

    The objective of the Sodium Loop Safety Facility (SLSF) W-2 experiment is to characterize the combined effects of a preconditioned full-length fuel column and slow transient overpower (TOP) conditions on breeder reactor (BR) fuel pin cladding failures. The W-2 experiment will meet this objective by providing data in two technological areas: (1) time and location of cladding failure, and (2) early post-failure test fuel behavior. The test involves a seven pin, prototypic full-length fast test reactor (FTR) fuel pin bundle which will be subjected to a simulated unprotected 5 cents/s reactivity transient overpower event. The outer six pins will provide the necessary prototypic thermal-hydraulic environment for the center pin.

  13. Road Map Team Proposal Form Proposal: P4

    E-print Network

    Suzuki, Masatsugu

    Road Map Team Proposal Form Proposal: P4 1: Road Map Team Name with other Road Map topics: This proposal is one of a set of strategies under the Philanthropy Road Map Team's best thinking about how to advance that goal through

  14. Athens Journal New York Times, Feb. 15, 2007, p.4

    E-print Network

    Columbia University

    groups to be the largest in Europe, is 520 feet high from partly treated sewage, toxic hospital wasteAthens Journal New York Times, Feb. 15, 2007, p.4 Greeks Have a Waste Problem, and No Hercules a European Union directive aimed at reducing the volume of waste in dumps, and it has been the scene of fires

  15. First LQCD Physics Runs with MILC and P4RHMC

    SciTech Connect

    Soltz, R; Gupta, R

    2007-01-18

    An initial series of physics LQCD runs were submitted to the BG/L science bank with the milc and p4rhmc. Both runs were for lattice dimensions of 32{sup 2} x 8. The p4 calculation was performed with v2.0 QMP{_}MPI.X (semioptomized p4 code using qmp over mpi) and milc v7.2, also using RHMC, but not specifically optimized for BlueGene. Calculations were performed along lines of constant physics, with the light quark masses 2-3 times their physics values and the strange quark mass set by m{sub ud} = 0.1m{sub s}. Job submissions was performed using the standard milc and p4 scripts provided on the ubgl cluster. Initial thermalized lattices for each code were also provided in this way. The only modifications for running on BG/L were to the directory names and the mT parameter which determines job durations (24 hrs on BG/L vs. 4 hrs on ubgl). The milc scripts were set to resubmit themselves 10 times, and the p4 scripts were submitted serially using the ''psub -d'' job dependency option. The runp4rhmc.tcsh could not be used to resubmit due to the 30m time limit imposed on interactive jobs. Most jobs were submitted to the smallest, 512 node partitions, but both codes could also run on the 1024 node partitions with a gain of only 30-50%. The majority of jobs ran without error. Stalled jobs were often indicative of a communication gap within a partition that LC was able to fix quickly. On some occasion a zero-length lattice file was deleted to allow jobs to restart successfully. Approximately 1000 trajectories were calculated for each beta value, see Table . The analysis was performed with the standard analysis scripts for each code, make{_}summary.pl for milc and analysis.tcsh for p4rhmc. All lattices, log files, and job submission scripts have been archived to permanent storage for subsequent analysis.

  16. Systems biology and p4 medicine: past, present, and future.

    PubMed

    Hood, Leroy

    2013-04-01

    Studying complex biological systems in a holistic rather than a "one gene or one protein" at a time approach requires the concerted effort of scientists from a wide variety of disciplines. The Institute for Systems Biology (ISB) has seamlessly integrated these disparate fields to create a cross-disciplinary platform and culture in which "biology drives technology drives computation." To achieve this platform/culture, it has been necessary for cross-disciplinary ISB scientists to learn one another's languages and work together effectively in teams. The focus of this "systems" approach on disease has led to a discipline denoted systems medicine. The advent of technological breakthroughs in the fields of genomics, proteomics, and, indeed, the other "omics" is catalyzing striking advances in systems medicine that have and are transforming diagnostic and therapeutic strategies. Systems medicine has united genomics and genetics through family genomics to more readily identify disease genes. It has made blood a window into health and disease. It is leading to the stratification of diseases (division into discrete subtypes) for proper impedance match against drugs and the stratification of patients into subgroups that respond to environmental challenges in a similar manner (e.g. response to drugs, response to toxins, etc.). The convergence of patient-activated social networks, big data and their analytics, and systems medicine has led to a P4 medicine that is predictive, preventive, personalized, and participatory. Medicine will focus on each individual. It will become proactive in nature. It will increasingly focus on wellness rather than disease. For example, in 10 years each patient will be surrounded by a virtual cloud of billions of data points, and we will have the tools to reduce this enormous data dimensionality into simple hypotheses about how to optimize wellness and avoid disease for each individual. P4 medicine will be able to detect and treat perturbations in healthy individuals long before disease symptoms appear, thus optimizing the wellness of individuals and avoiding disease. P4 medicine will 1) improve health care, 2) reduce the cost of health care, and 3) stimulate innovation and new company creation. Health care is not the only subject that can benefit from such integrative, cross-disciplinary, and systems-driven platforms and cultures. Many other challenges plaguing our planet, such as energy, environment, nutrition, and agriculture can be transformed by using such an integrated and systems-driven approach. PMID:23908862

  17. Systems Biology and P4 Medicine: Past, Present, and Future

    PubMed Central

    Hood, Leroy

    2013-01-01

    Studying complex biological systems in a holistic rather than a “one gene or one protein” at a time approach requires the concerted effort of scientists from a wide variety of disciplines. The Institute for Systems Biology (ISB) has seamlessly integrated these disparate fields to create a cross-disciplinary platform and culture in which “biology drives technology drives computation.” To achieve this platform/culture, it has been necessary for cross-disciplinary ISB scientists to learn one another’s languages and work together effectively in teams. The focus of this “systems” approach on disease has led to a discipline denoted systems medicine. The advent of technological breakthroughs in the fields of genomics, proteomics, and, indeed, the other “omics” is catalyzing striking advances in systems medicine that have and are transforming diagnostic and therapeutic strategies. Systems medicine has united genomics and genetics through family genomics to more readily identify disease genes. It has made blood a window into health and disease. It is leading to the stratification of diseases (division into discrete subtypes) for proper impedance match against drugs and the stratification of patients into subgroups that respond to environmental challenges in a similar manner (e.g. response to drugs, response to toxins, etc.). The convergence of patient-activated social networks, big data and their analytics, and systems medicine has led to a P4 medicine that is predictive, preventive, personalized, and participatory. Medicine will focus on each individual. It will become proactive in nature. It will increasingly focus on wellness rather than disease. For example, in 10 years each patient will be surrounded by a virtual cloud of billions of data points, and we will have the tools to reduce this enormous data dimensionality into simple hypotheses about how to optimize wellness and avoid disease for each individual. P4 medicine will be able to detect and treat perturbations in healthy individuals long before disease symptoms appear, thus optimizing the wellness of individuals and avoiding disease. P4 medicine will 1) improve health care, 2) reduce the cost of health care, and 3) stimulate innovation and new company creation. Health care is not the only subject that can benefit from such integrative, cross-disciplinary, and systems-driven platforms and cultures. Many other challenges plaguing our planet, such as energy, environment, nutrition, and agriculture can be transformed by using such an integrated and systems-driven approach. PMID:23908862

  18. p4-Linda: A portable implementation of Linda

    SciTech Connect

    Butler, R.M.; Leveton, A.L. [University of North Florida, Jacksonville, FL (United States). Div. of Computer and Information Science; Lusk, E.L. [Argonne National Lab., IL (United States)

    1993-07-01

    Facilities such as interprocess communication and protection of shared resources have been added to operating systems to support multiprogramming and have since been adapted to exploit explicit multiprocessing within the scope of two models: the shared-memory model and the distributed (message-passing) model. When multiprocessors (or networks of heterogeneous processors) are used for explicit parallelism, the difference between these models is exposed to the programmer. The p4 tool set was originally developed to buffer the programmer from synchronization issues while offering an added advantage in portability, however two models are often still needed to develop parallel algorithms. We provide two implementations of Linda in an attempt to support a single high-level programming model on top of the existing paradigms in order to provide a consistent semantics regardless of the underlying model. Linda`s fundamental properties associated with generative communication eliminate the distinction between shared and distributed memory.

  19. LQCD Phase 1 Runs with P4RHMC

    SciTech Connect

    Soltz, R; Gupta, R

    2007-02-13

    These results represent the first set of runs of 10 {beta} values ranging from 2000-7000 trajectories with the p4rhmc code. This initial run sequence spanned roughly 2-weeks in late January and Early February, 2007. To manage the submission of dependent jobs: subSet.pl--submits a set of dependent jobs for a single run; rmSet.pl--removes a set of dependent jobs in reverse order of submission; and statSet.pl--runs pstat command and prints parsed output along with directory contents. The results of running the statSet.pl command are printed for three different times during the start up the next sequence of runs using the milc code.

  20. Inversion by P4: polarization-picture post-processing

    PubMed Central

    Schechner, Yoav Y.

    2011-01-01

    Polarization may be sensed by imaging modules. This is done in various engineering systems as well as in biological systems, specifically by insects and some marine species. However, polarization per pixel is usually not the direct variable of interest. Rather, polarization-related data serve as a cue for recovering task-specific scene information. How should polarization-picture post-processing (P4) be done for the best scene understanding? Answering this question is not only helpful for advanced engineering (computer vision), but also to prompt hypotheses as to the processing occurring within biological systems. In various important cases, the answer is found by a principled expression of scene recovery as an inverse problem. Such an expression relies directly on a physics-based model of effects in the scene. The model includes analysis that depends on the different polarization components, thus facilitating the use of these components during the inversion, in a proper, even if non-trivial, manner. We describe several examples for this approach. These include automatic removal of path radiance in haze or underwater, overcoming partial semireflections and visual reverberations; three-dimensional recovery and distance-adaptive denoising. The resulting inversion algorithms rely on signal-processing methods, such as independent component analysis, deconvolution and optimization. PMID:21282167

  1. Supporting Information For: Removal of Covalent Heterogeneity Reveals Simple Folding Behavior for P4-P6 RNA

    E-print Network

    Herschlag, Dan

    running as the unfolded band on a 1 mM Mg2+ native gel. Quantification of the experiments described in Fig. (D) Same molecules as in (C) after unfolding in 10 mM EDTA and 100 mM Na+ for 10 minutes distributions. #12;S3 Figure S2. Folded and unfolded P4-P6 RNA purified by native gel (1 mM Mg2+ ) do

  2. Caspase-3 binds diverse P4 residues in peptides as revealed by crystallography and structural modeling.

    SciTech Connect

    Fang, Bin; Fu, Guoxing; Agniswamy, Johnson; Harrison, Robert W.; Weber, Irene T.; (GSU)

    2009-03-31

    Caspase-3 recognition of various P4 residues in its numerous protein substrates was investigated by crystallography, kinetics, and calculations on model complexes. Asp is the most frequent P4 residue in peptide substrates, although a wide variety of P4 residues are found in the cellular proteins cleaved by caspase-3. The binding of peptidic inhibitors with hydrophobic P4 residues, or no P4 residue, is illustrated by crystal structures of caspase-3 complexes with Ac-IEPD-Cho, Ac-WEHD-Cho, Ac-YVAD-Cho, and Boc-D(OMe)-Fmk at resolutions of 1.9-2.6 {angstrom}. The P4 residues formed favorable hydrophobic interactions in two separate hydrophobic regions of the binding site. The side chains of P4 Ile and Tyr form hydrophobic interactions with caspase-3 residues Trp206 and Trp214 within a non-polar pocket of the S4 subsite, while P4 Trp interacts with Phe250 and Phe252 that can also form the S5 subsite. These interactions of hydrophobic P4 residues are distinct from those for polar P4 Asp, which indicates the adaptability of caspase-3 for binding diverse P4 residues. The predicted trends in peptide binding from molecular models had high correlation with experimental values for peptide inhibitors. Analysis of structural models for the binding of 20 different amino acids at P4 in the aldehyde peptide Ac-XEVD-Cho suggested that the majority of hydrophilic P4 residues interact with Phe250, while hydrophobic residues interact with Trp206, Phe250, and Trp214. Overall, the S4 pocket of caspase-3 exhibits flexible adaptation for different residues and the new structures and models, especially for hydrophobic P4 residues, will be helpful for the design of caspase-3 based drugs.

  3. Vascular Endothelial Growth Factor (VEGF) mRNA Isoforms are Altered in Bovine Granulosa Cells (GC) by Circulating Progestin Concentrations (P4) and May Indicate Follicle Status and Oocyte Competence

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Previously, Melengestrol Acetate (MGA) fed for 14 d (0.5mg/cow/d; < 1 ng/ml P4) resulted in persistent follicles with increased size, decreased number of GC/follicular fluid (FF) volume, and less fertile oocytes. An experiment was conducted to determine effects of circulating P4 on amount of mRNA fo...

  4. Mechanisms of genome propagation and helper exploitation by satellite phage P4.

    PubMed Central

    Lindqvist, B H; Dehò, G; Calendar, R

    1993-01-01

    Temperate coliphage P2 and satellite phage P4 have icosahedral capsids and contractile tails with side tail fibers. Because P4 requires all the capsid, tail, and lysis genes (late genes) of P2, the genomes of these phages are in constant communication during P4 development. The P4 genome (11,624 bp) and the P2 genome (33.8 kb) share homologous cos sites of 55 bp which are essential for generating 19-bp cohesive ends but are otherwise dissimilar. P4 turns on the expression of helper phage late genes by two mechanisms: derepression of P2 prophage and transactivation of P2 late-gene promoters. P4 also exploits the morphopoietic pathway of P2 by controlling the capsid size to fit its smaller genome. The P4 sid gene product is responsible for capsid size determination, and the P2 capsid gene product, gpN, is used to build both sizes. The P2 capsid contains 420 capsid protein subunits, and P4 contains 240 subunits. The size reduction appears to involve a major change of the whole hexamer complex. The P4 particles are less stable to heat inactivation, unless their capsids are coated with a P4-encoded decoration protein (the psu gene product). P4 uses a small RNA molecule as its immunity factor. Expression of P4 replication functions is prevented by premature transcription termination effected by this small RNA molecule, which contains a sequence that is complementary to a sequence in the transcript that it terminates. Images PMID:8246844

  5. Detection and characterization of a human G9P[4] rotavirus strain in Japan.

    PubMed

    Yamamoto, Seiji P; Kaida, Atsushi; Ono, Atsushi; Kubo, Hideyuki; Iritani, Nobuhiro

    2015-08-01

    In a surveillance system in Osaka City, Japan, 48 sporadic rotavirus A (RVA) infections were detected during 2008/2009-2011/2012 seasons. The G/P-genotypes of detected RVAs were G1P[8], G2P[4], G3P[8], G9P[4], and G9P[8]. Although G9P[4] is a rare genotype that had not been reported in Japan, it was the second most prevalent genotype, following G1P[8], and accounted for 35.3% of RVA cases in the 2011/2012 season. Further genotyping revealed that the G9P[4] strain had genotype 2 internal protein genes except for NSP3: G9-P[4]-I2-R2-C2-M2-A2-N2-T1-E2-H2. Among detected RVA strains, G9P[4] and some G9P[8] strains shared high nucleotide identity in VP7 and NSP3 genes. Phylogenetic and BLAST search analyses showed that the G9P[4] strain in Japan shared high nucleotide identity in genotype 2 genes with common G2P[4] strains circulating globally, but was distinct from other G9P[4] strains circulating worldwide. These results suggest that the G9P[4] strain in Japan may have emerged through an independent reassortment between G9P[8] and G2P[4]. Finally, the role of NSP3 protein in the circulating RVA from an amino acid comparison between T1- and T2-type NSP3 is discussed. These findings provide an important insight into less problematic combinations of circulating RVA genes derived from different genotypes. J. Med. Virol. 87:1311-1318, 2015. © 2015 Wiley Periodicals, Inc. PMID:25907907

  6. Transcriptional profiling of genes involved in n-hexadecane compounds assimilation in the hydrocarbon degrading Dietzia cinnamea P4 strain

    PubMed Central

    Procópio, Luciano; de Cassia Pereira e Silva, Michele; van Elsas, Jan Dirk; Seldin, Lucy

    2013-01-01

    The petroleum-derived degrading Dietzia cinnamea strain P4 recently had its genome sequenced and annotated. This allowed employing the data on genes that are involved in the degradation of n-alkanes. To examine the physiological behavior of strain P4 in the presence of n-alkanes, the strain was grown under varying conditions of pH and temperature. D. cinnamea P4 was able to grow at pH 7.0–9.0 and at temperatures ranging from 35 ºC to 45 ºC. Experiments of gene expression by real-time quantitative RT-PCR throughout the complete growth cycle clearly indicated the induction of the regulatory gene alkU (TetR family) during early growth. During the logarithmic phase, a large increase in transcriptional levels of a lipid transporter gene was noted. Also, the expression of a gene that encodes the protein fused rubredoxin-alkane monooxygenase was enhanced. Both genes are probably under the influence of the AlkU regulator. PMID:24294263

  7. GPS Solutions:Closed Forms, Criticaland Special Configurations of P4P

    E-print Network

    Shan, Jie

    . Such an analysis of critical P4P extends results obtained for satellite laser ranging (Killian & Meissl, 1969, IN 47907 P4P is the pseudo-mnging 4-point problem as it appears as the basic configuration of satellite positioning with pseudo-ranges as observables.In order to determine the ground receiver/ satellite receiver

  8. p-(4-Azipentyl)-propofol: A Potent Photoreactive General Anesthetic Derivative of Propofol

    PubMed Central

    Stewart, Deirdre S.; Savechenkov, Pavel Y.; Dostalova, Zuzana; Chiara, David C.; Ge, Rile; Raines, Douglas E.; Cohne, Jonathan B.; Forman, Stuart A.; Bruzik, Karol S.; Miller, Keith W.

    2013-01-01

    We synthesized 2,6-Diisopropyl-4-[3-(3-methyl-3H-diazirin-3-yl)-propyl]-phenol (p-(4-azipentyl)-propofol), or p-4-AziC5-Pro, a novel photoactivable derivative of the general anesthetic propofol. p-4-AziC5-Pro has an anesthetic potency similar to propofol. Like propofol, the compound potentiates inhibitory GABAA receptor current responses and allosterically modulates binding to both agonist and benzodiazepine sites, assayed on heterologously expressed GABAA receptors. p-4-AziC5-Pro inhibits excitatory current responses of nACh receptors expressed in Xenopus oocytes and photoincorporates into native nACh receptor-enriched Torpedo membranes. Thus p-4-AziC5-Pro is a functional general anesthetic that both modulates and photoincorporates into Cys-loop ligand-gated ion channels, making it an excellent candidate for use in identifying propofol binding sites. PMID:22029276

  9. The P4 truss is moved to a workstand in the SSPF

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Suspended by an overhead crane in the Space Station Processing Facility, the International Space Station's P4 truss moves toward a workstand. Below and behind it on the floor is the Multi- Purpose Logistics Module Raffaello, another segment of the Space Station. Part of the 10-truss, girder-like structure that will ultimately extend the length of a football field, the P4 is the second port truss segment that will attach to the first port truss segment (P1 truss). The P4 is scheduled for mission 12A in September 2002.

  10. 77 FR 26014 - Prospective Grant of Exclusive License: P4 Peptide From Streptococcus Pneumoniae

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-02

    ...Use of P4 as either a carrier and/or immunoenhancer in a polysaccharide vaccine conjugate for prevention of Streptococcus pneumonia infection in humans'') to practice the inventions embodied in the patent application referred to below to Viper...

  11. Phytosphingosine 1-phosphate: a high affinity ligand for the S1P 4\\/Edg-6 receptor

    Microsoft Academic Search

    Mari Rios Candelore; Michael J Wright; Laurie M Tota; James Milligan; Gan-ju Shei; James D Bergstrom; Suzanne M Mandala

    2002-01-01

    It has been reported recently that the phosphorylated form of the immunomodulator FTY720 activates sphingosine 1-phosphate G protein-coupled receptors [1,2]. Therefore, understanding the biology of this new class of receptors will be important in clarifying the immunological function of bioactive lysosphingolipid ligands. The S1P4 receptor has generated interest due to its lymphoid tissue distribution. While the S1P4 receptor binds the

  12. Plasma diagnostic potential of 2p4f in N$^+$ -- accurate wavelengths and oscillator strengths

    E-print Network

    Shen, Xiaozhi; Jönsson, Per; Wang, Jianguo

    2015-01-01

    Radiative emission lines from nitrogen and its ions are often observed in nebulae spectra, where the N$^{2+}$ abundance can be inferred from lines of the 2p4f configuration. In addition, intensity ratios between lines of the 2p3p -- 2p3s and 2p4f -- 2p3d transition arrays can serve as temperature diagnostics. To aid abundance determinations and plasma diagnostics, wavelengths and oscillator strengths were calculated with high-precision for electric-dipole (E1) transitions from levels in the 2p4f configuration of N$^{+}$. Electron correlation and relativistic effects, including the Breit interaction, were systematically taken into account within the framework of the multiconfiguration Dirac-Hartree-Fock (MCDHF) method. Except for the 2p4f - 2p4d transitions with quite large wavelengths and the two-electron-one-photon 2p4f -2s2p$^3$ transitions, the uncertainties of the present calculations were controlled to within 3% and 5% for wavelengths and oscillator strengths, respectively. We also compared our results w...

  13. Plasma Diagnostic Potential of 2p4f in N+—Accurate Wavelengths and Oscillator Strengths

    NASA Astrophysics Data System (ADS)

    Shen, Xiaozhi; Li, Jiguang; Jönsson, Per; Wang, Jianguo

    2015-03-01

    Radiative emission lines from nitrogen and its ions are often observed in nebula spectra, where the N2 + abundance can be inferred from lines of the 2p4f configuration. In addition, intensity ratios between lines of the 2p3p-2p3s and 2p4f-2p3d transition arrays can serve as temperature diagnostics. To aid abundance determinations and plasma diagnostics, wavelengths and oscillator strengths were calculated with high precision for electric dipole (E1) transitions from levels in the 2p4f configuration of N+. Electron correlation and relativistic effects, including the Breit interaction, were systematically taken into account within the framework of the multiconfiguration Dirac-Hartree-Fock method. Except for the 2p4f-2p4d transitions with quite large wavelengths and the two-electron-one-photon 2p4f-2s2p 3 transitions, the uncertainties of the present calculations were controlled to within 3% and 5% for wavelengths and oscillator strengths, respectively. We also compared our results with other theoretical and experimental values when available. Discrepancies were found between our calculations and previous calculations due to the neglect of relativistic effects in the latter.

  14. Biosynthesis and characterization of polyhydroxyalkanoate block copolymer P3HB-b-P4HB.

    PubMed

    Hu, Die; Chung, Ah-Leum; Wu, Lin-Ping; Zhang, Xin; Wu, Qiong; Chen, Jin-Chun; Chen, Guo-Qiang

    2011-09-12

    Polyhydroxyalkanoates (PHA) synthesis genes phbC and orfZ cloned from Ralstonia eutropha H16 were transformed into beta-oxidation weakened Pseudomonas putida KTOY08?GC, a mutant of P. putida KT2442. The recombinant P. putida strain termed KTHH06 was able to produce a short-chain-length PHA block copolymer consisting of poly(3-hydroxybutyrate) (P3HB) as one block and poly(4-hydroxybutyrate) (P4HB) as another block. One-dimensional and two-dimensional nuclear magnetic resonance (NMR) clearly indicated the polymer was a diblock copolymer consisting of 20 mol % P3HB as one block and 80 mol % P4HB as another one. Differential scanning calorimetric (DSC) showed that P3HB block melting temperatures (T(m)) in the block copolymer P3HB-b-P4HB was shift to low temperature compared with homopolymer P3HB and a blend of P3HB and P4HB. The block copolymer with a number average molecular weight of 50000 Da and a polydispersity of 3.1 demonstrated a better yield and tensile strength compared with that of its related random copolymer and blend of homopolymers of P3HB and P4HB. PMID:21863836

  15. Helix P4 is a divalent metal ion binding site in the conserved core of the ribonuclease P ribozyme.

    PubMed Central

    Christian, E L; Kaye, N M; Harris, M E

    2000-01-01

    The ribonuclease P ribozyme (RNase P RNA), like other large ribozymes, requires magnesium ions for folding and catalytic function; however, specific sites of metal ion coordination in RNase P RNA are not well defined. To identify and characterize individual nucleotide functional groups in the RNase P ribozyme that participate in catalytic function, we employed self-cleaving ribozyme-substrate conjugates that facilitate measurement of the effects of individual functional group modifications. The self-cleavage rates and pH dependence of two different ribozyme-substrate conjugates were determined and found to be similar to the single turnover kinetics of the native ribozyme. Using site-specific phosphorothioate substitutions, we provide evidence for metal ion coordination at the pro-Rp phosphate oxygen of A67, in the highly conserved helix P4, that was previously suggested by modification-interference experiments. In addition, we detect a new metal ion coordination site at the pro-Sp phosphate oxygen of A67. These findings, in combination with the proximity of A67 to the pre-tRNA cleavage site, support the conclusion that an important role of helix P4 in the RNase P ribozyme is to position divalent metal ions that are required for catalysis. PMID:10786842

  16. Novel type of plasmin inhibitors: Providing insight into P4 moiety and alternative scaffold to pyrrolopyrimidine.

    PubMed

    Teno, Naoki; Gohda, Keigo; Wanaka, Keiko; Tsuda, Yuko; Akagawa, Maiko; Akiduki, Eriko; Araki, Mitsuhito; Masuda, Arisa; Otsubo, Tadamune; Yamashita, Yukiko

    2015-07-01

    Here we report a series of plasmin inhibitors which were originally derived from the parent structure of 1 and 2. Our efforts focused on the optimization of the P4 moiety of 2 and on the quest of alternative scaffold to pyrrolopyrimidine in the parent compounds. The results of the former gave us pivotal information on the further optimization of the P4 moiety in plasmin inhibitors and those of the latter revealed that appropriate moieties extending from the benzimidazole scaffold engaged with S4 pocket in the active site of plasmin. PMID:25921265

  17. P4.37 INTER-COMPARISON OF GOES-8 IMAGER AND SOUNDER SKIN TEMPERATURE RETRIEVALS

    E-print Network

    Haines, Stephanie L.

    observed in GOES-8 and GOES-11 calibrated IR images and analyzing the averaging of ST retrievals fromP4.37 INTER-COMPARISON OF GOES-8 IMAGER AND SOUNDER SKIN TEMPERATURE RETRIEVALS Stephanie L. Haines (GOES) data at the Global Hydrology and Climate Center (GHCC). The GOES Imager or Sounder data are used

  18. Solution structure and metal ion binding sites of the human CPEB3 ribozyme's P4 domain.

    PubMed

    Skilandat, Miriam; Rowinska-Zyrek, Magdalena; Sigel, Roland K O

    2014-08-01

    Three ribozymes are known to occur in humans, the CPEB3 ribozyme, the CoTC ribozyme, and the hammerhead ribozyme. Here, we present the NMR solution structure of a well-conserved motif within the CPEB3 ribozyme, the P4 domain. In addition, we discuss the binding sites and impact of Mg(2+) and [Co(NH3)6](3+), a spectroscopic probe for [Mg(H2O)6](2+), on the structure. The well-defined P4 region is a hairpin closed with a UGGU tetraloop that shows a distinct electrostatic surface potential and a characteristic, strongly curved backbone trajectory. The P4 hairpin contains two specific Mg(2+) binding sites: one outer-sphere binding site close to the proposed CPEB3 ribozyme active site with potential relevance for maintaining a compact fold of the ribozyme core, and one inner-sphere binding site, probably stabilizing the tetraloop structure. The structure of the tetraloop resembles an RNase III recognition structure, as previously described for an AGUU tetraloop. The detailed knowledge of the P4 domain and its metal ion binding preferences thus brings us closer to understanding the importance of Mg(2+) binding for the CPEB3 ribozyme's fold and function in the cell. PMID:24652468

  19. THE BIANCHI IDENTITIES, ELECTROMAGNETIC WAVES, AND CHARGE CONSERVATION IN THE P(4) THEORY OF

    E-print Network

    Norris, Larry K.

    THE BIANCHI IDENTITIES, ELECTROMAGNETIC WAVES, AND CHARGE CONSERVATION IN THE P(4) THEORY-energy-momentum and the wave equation for the Lanczos H-tensor. #12;§1. Introduction. A fundamental feature of the general) theory one obtains a conservation law and a wave equation for the electromagnetic field that parallels

  20. Orally bioavailable factor Xa inhibitors containing alpha-substituted gem-dimethyl P4 moieties.

    PubMed

    Orwat, Michael J; Qiao, Jennifer X; He, Kan; Rendina, Alan R; Luettgen, Joseph M; Rossi, Karen A; Xin, Baomin; Knabb, Robert M; Wexler, Ruth R; Lam, Patrick Y S; Pinto, Donald J P

    2014-08-01

    In an effort to identify a potential back-up to apixaban (Eliquis®), we explored a series of diversified P4 moieties. Several analogs with substituted gem-dimethyl moieties replacing the terminal lactam of apixaban were identified which demonstrated potent FXa binding affinity (FXa Ki), good human plasma anticoagulant activity (PT EC2x), cell permeability, and oral bioavailability. PMID:24951330

  1. P4.19 LAND SURFACE TEMPERATURE RETRIEVALS FROM GOES-8 USING EMISSIVITIES RETRIEVED FROM MODIS

    E-print Network

    Haines, Stephanie L.

    P4.19 LAND SURFACE TEMPERATURE RETRIEVALS FROM GOES-8 USING EMISSIVITIES RETRIEVED FROM MODIS instruments is MODIS. The MODIS instruments on NASA's Aqua and Terra satellites have spectral channels of the physical parameters produced by the EOS MODIS land surface team that can have a positive impact

  2. Merging P4P and Disease Management: How Do You Know Which One Is Working?

    Microsoft Academic Search

    ALLEN L. SMITH

    2007-01-01

    BACKGROUND: An intervention movement in managed care, disease manage- ment (DM), is a system of coordinated health care interventions and communi- cation for populations with conditions in which patient self-care efforts are sig- nificant. Another managed care intervention movement, pay for performance (P4P), involves an incentive component in which payment is defined based on meeting specific, previously agreed-upon process or

  3. Performance evaluation of the microPET P4: a PET system dedicated to animal imaging

    Microsoft Academic Search

    Y. C. Tai; A. Chatziioannou; S. Siegel; J. Young; D. Newport; R. N. Goble; R. E. Nutt; S. R. Cherry

    2001-01-01

    The microPET Primate 4-ring system (P4) is an animal PET tomograph with a 7.8 cm axial extent, a 19 cm diameter transaxial field of view (FOV) and a 22 cm animal port. The system is composed of 168 detector modules, each with an 8×8 array of 2.2×2.2×10 mm3 lutetium oxyorthosilicate crystals, arranged as 32 crystal rings 26 cm in diameter.

  4. Mammalian P4-ATPases and ABC Transporters And Their Role in Phospholipid Transport

    PubMed Central

    Coleman, Jonathan A.; Quazi, Faraz; Molday, Robert S.

    2012-01-01

    Transport of phospholipids across cell membranes plays a key role in a wide variety of biological processes. These include membrane biosynthesis, generation and maintenance of membrane asymmetry, cell and organelle shape determination, phagocytosis, vesicle tranfficking, blood coagulation, lipid homeostasis, regulation of membrane protein function, apoptosis among others. P4-ATPases and ATP binding cassette (ABC) transporters are the two principal classes of membranes proteins that actively transport phospholipids across cellular membranes. P4-ATPases utilize the energy from ATP hydrolysis to flip aminophospholipids from the exocytoplasmic (extracellular/lumen) to the cytoplasmic leaflet of cell membranes generating membrane lipid asymmetry and lipid imbalance which can induce membrane curvature. Many ABC transporters play crucial roles in lipid homeostasis by actively transporting phospholipids from the cytoplasmic to the exocytoplasmic leaflet of cell membranes or exporting phospholipids to protein acceptors or micelles. Recent studies indicate that some ABC proteins can also transport phospholipids in the opposite direction. The importance of P4-ATPases and ABC transporters is evident from the findings that mutations in many of these transporters are responsible for severe human genetic diseases linked to defective phospholipid transport. PMID:23103747

  5. Generalized spin polarizabilities of the nucleon in Heavy Baryon Chiral Perturbation Theory at order ${\\mathcal O}(p^4)$

    E-print Network

    Chung Wen Kao; Marc Vanderhaeghen

    2002-11-07

    We present the first heavy baryon chiral perturbation theory calculation at ${\\mathcal O}(p^4)$ for the spin-dependent amplitudes for virtual Compton scattering off the nucleon, and extract the ${\\cal O}(p^4)$ order results for the generalized spin polarizabilities of the nucleon.

  6. Crystal Structure of Pb 5Bi 18P 4O 42: A Fluorite-Related Superstructure

    Microsoft Academic Search

    Sophie Giraud; Jean-Pierre Wignacourt; Steve Swinnea; Hugo Steinfink; Richard Harlow

    2000-01-01

    Single crystals of a new oxyphosphate of bismuth and lead, Pb5Bi18P4O42, were studied using short-wavelength synchrotron X-ray radiation. The compound is monoclinic, I2\\/m, a=11.885(2) Å, b=11.540(2) Å, c=15.636(3) Å, ?=90.23(3)°, Z=2. The crystal is twinned by pseudo-merohedry. The structure refinement converged to R=0.0366. There are five crystallographically independent Bi atoms. The oxygen coordination polyhedron around Bi(1) is a slightly distorted

  7. Functionalization of P4 using a Lewis acid stabilized bicyclo[1.1.0]tetraphosphabutane anion.

    PubMed

    Borger, Jaap E; Ehlers, Andreas W; Lutz, Martin; Slootweg, J Chris; Lammertsma, Koop

    2014-11-17

    Reacting white phosphorus (P4 ) with sterically encumbered aryl lithium reagents (aryl=2,6-dimesitylphenyl or 2,4,6-tBu3 C6 H2 ) and B(C6 F5 )3 gives the unique, isolable Lewis acid stabilized bicyclo[1.1.0]tetraphosphabutane anion. Subsequent alkylation of the nucleophilic site of the RP4 anion gives access to non-symmetrical disubstituted bicyclic tetraphosphorus compounds. This novel method enables P?C bond formation in a controlled fashion using white phosphorus as starting material. PMID:25250790

  8. Dihydrogen tetrametaphosphate, [P4O12H2]2-: synthesis, solubilization in organic media, preparation of its anhydride [P4O11]2- and acidic methyl ester, and conversion to tetrametaphosphate metal complexes via protonolysis.

    PubMed

    Jiang, Yanfeng; Chakarawet, Khetpakorn; Kohout, Andrea Laura; Nava, Matthew; Marino, Nadia; Cummins, Christopher C

    2014-08-27

    Dihydrogen tetrametaphosphate [P4O12H2](2-) (1) can now be synthesized and isolated as its PPN salt ([PPN](+) = [N(PPh3)2](+)) via treatment of [PPN]4[P4O12] with trifluoroacetic anhydride in wet acetone; this simple procedure affords the oxoacid salt in 94% yield. A pKa of 15.83 ± 0.11 in acetonitrile was determined. [P4O12H2](2-) reacts with the dehydrating agent N,N'-dicyclohexylcarbodiimide to afford tetrametaphosphate anhydride [P4O11](2-) (2) in 82% yield, also as the PPN salt. From 2 a monohydrogen tetrametaphosphate ester [P4O10(OH)(OMe)](2-) (3, 96%) was derived by addition of methanol, illustrating that 2 can function as a reagent for chemical phosphorylation. Addition of water to 2 regenerates 1 quantitatively. Deprotonation of 1 by metal amides in the +2 oxidation state led to the unconventional monomeric tin(II) ?(4) tetrametaphosphate [Sn(P4O12)](2-) (4, 78%, a molecular analog of SnO) and binary dimeric chromium(II) bis(?2,?(2),?(2)) derivative [Cr2(P4O12)2](4-) (5, 82%). Structural data stemming from single-crystal X-ray diffraction studies for the PPN salts of anions 1-5 are also reported. PMID:25102033

  9. Rotavirus G2P[4] detection in fresh vegetables and oysters in Mexico City.

    PubMed

    Quiroz-Santiago, Carolina; Vázquez-Salinas, Carlos; Natividad-Bonifacio, Ivan; Barrón-Romero, Blanca Lilia; Quiñones-Ramírez, Elsa Irma

    2014-11-01

    Rotaviruses are the principal cause of dehydration caused by diarrhea in children younger than 2 years of age. Although these viral infections have mainly been associated with ingestion of fecally contaminated food and water, few studies have addressed the presence of the virus in food that is consumed raw or slightly cooked. In this work, 30 oyster samples and 33 vegetable samples were examined for the presence of rotavirus genotypes to evaluate their potential to produce gastrointestinal infections. The rotaviruses were identified by reverse transcriptase PCR amplification of the VP7 gene. G and P genotyping was also performed by reverse transcriptase PCR, with a detection sensitivity of up to 15 PFU/ml. Rotaviruses were found in 17 (26.9%) of 63 samples (10 oysters and 7 vegetables). The G2 genotype was found in 11 (64.7%) of 17 of the rotavirus strains, and 16 (94.1%) of 17 had the P[4] genotype. The combined genotypes found most frequently were G2P[4] (10 [58.82%] of 17), GNTP[4] (6 [35.29%] of 17), and G2P[NT] (1 [5.8%] of 17). PMID:25364930

  10. Biosynthesis and characterization of diblock copolymer of p(3-hydroxypropionate)-block-p(4-hydroxybutyrate) from recombinant Escherichia coli.

    PubMed

    Tripathi, Lakshmi; Wu, Lin-Ping; Meng, Dechuan; Chen, Jinchun; Chen, Guo-Qiang

    2013-03-11

    Poly(4-hydroxybutyrate) (P4HB) is a highly elastic polymer, whereas poly(3-hydroxypropionate) (P3HP) is a polymer with enormous tensile strength. This study aimed to biosynthesize a block copolymer consisting of soft P4HB block with a strong P3HP block to gain unique and excellent material properties. A recombinant Escherichia coli strain that produces homopolymers of P3HP and P4HB was employed for the block copolymer synthesis. When the strain was grown in the presence of 1,4-butanediol (BDO) as a 4HB precursor, P4HB block was formed. Sequential supplementation of 1,3-propanediol (PDO) as a 3HP precursor allowed the strain to produce P3HP block. Thermal, NMR, fractionation, and mechanical characterizations confirmed the resulting polymer as a block copolymer of P3HP-b-P4HB. Two block copolymers were formed from this study, including the P3HP-b-29% P4HB and P3HP-b-37% P4HB, they showed superior properties over random copolymers P(3HP-co-4HB). The block copolymers had two glass transition temperatures (Tg) and two melting temperatures (Tm). In comparison to the homopolymers P3HP and P4HB, incorporation of block microstructure resulted in the lowering of Tm, block copolymers were revealed with higher Young's modulus, yield strengths, and tension strengths much better than the previously reported random copolymers of similar compositions. Block copolymerization of P3HP and P4HB adds a new vision on PHA polymerization by generation of new polymers with superior properties. PMID:23351169

  11. Characterization of the P4 promoter region of the human insulin-like growth factor II gene.

    PubMed

    Hyun, S W; Kim, S J; Park, K; Rho, H M; Lee, Y I

    1993-10-11

    The human insulin-like growth factor II (IGF-II) gene contains four promoters (P1, P2, P3 and P4). In order to determine the mechanism by which the P4 promoter is controlled, the human IGF-II P4 promoter was analyzed in cell lines. DNA sequence analysis of the human IGF-II P4 promoter gene showed that the P4 promoter region contains a TATA-like sequence and several G+C rich regions which are essential for transcription. Analysis of the transcription initiation site by S1 nuclease mapping revealed two transcription start sites; both are located immediately behind TATA-like sequence. To determine the location of sites that may be important for the function of the human IGF-II P4 promoter, we constructed chimeric genes of the human IGF-II P4 promoter fused to the coding region for chloramphenicol acetyltransferase (CAT). These constructs were transfected into HepG2, PLC/PRF/5, G401 and A549 cells, and were examined for CAT activity. All transfected cells showed a similar profile of CAT activity. Sequences responsible for putative enhancer and silencer regions were identified and the 5' flanking sequences of the human IGF-II P4 promoter contain negative regulatory regions (-213 to -174). The 53-base pair fragment located between 111 and 59 base pairs upstream of the start site contains positive regulatory activity. Gel mobility shift assay showed that Sp1 and another proteins might be involved in positive regulation of the human IGF-II P4 promoter. PMID:8405433

  12. 3He(d, p)4He Reaction at Intermediate Energies

    NASA Astrophysics Data System (ADS)

    Uesaka, T.; Satou, Y.; Sakamoto, N.; Itoh, K.; Sakai, H.; Tamii, A.; Ohnishi, T.; Sekiguchi, K.; Yako, K.; Sakoda, S.; Okamura, H.; Suda, K.; Wakasa, T.

    2000-10-01

    We have measured the cross sections and the polarization observables for the 3He(d,p)4He reaction at Ed =140, 200, and 270 MeV. This work aims to investigate the high momentum component of deuteron D-state wave function and the mechanism for the one-nucleon transfer reaction at intermediate energies. The measurement was carried out by using the spectrograph SMART at RIKEN Accelerator Research Facility. A cryogenic 3He gas target with a density of 6.6 ×1020 cm-3 was bombarded by a polarized deuteron beam. The data are compared with the calculation based on the one-nucleon exchange approximation and data from the d + p backward scattering.

  13. Measurements of spin observables for the p-->-4He elastic scattering at 800 MeV

    NASA Astrophysics Data System (ADS)

    Geso, M.; Adams, D.; Bysterisky, J.; Igo, G.; Ling, A.; Whitten, C.; Nasser, M.; Smith, L. C.; Whitney, R. W.

    1998-12-01

    Experimental measurements of the spin transfer observables (Dss, Dsl, Dll, and Dls) for p-4He elastic scattering at 800 MeV are reported. The spin rotation parameters Q and S are also deduced from the spin transfer observables. Measurements were made in the angular range of 6°

  14. Crystal and electronic structure of La 3Zn 2? x P 4 – New phosphide with isolated P 3? species

    Microsoft Academic Search

    Hannes Lincke; Tom Nilges; Dirk Johrendt; Rainer Pöttgen

    2008-01-01

    The new phosphide La3Zn2?xP4 was synthesized from lanthanum, LaZn and red phosphorous in a NaCl\\/KCl halide flux at 1120K. La3Zn2?xP4 crystallizes with a new structure type: R3¯m, a=418.72(7), c=4143.7(1)pm, wR2=0.0577, 1061 F2 values for La3Zn1.75P4 and a=418.99(6), c=4157.1(8)pm, wR2=0.0485, 337 F2 values for La3Zn1.88P4 with 17 variables per refinement. The P3? phosphide anions show an hhcc stacking sequence, similar to

  15. Antitumor activity of G-quadruplex-interactive agent TMPyP4 with photodynamic therapy in ovarian carcinoma cells

    PubMed Central

    LIU, HONGLI; LV, CHANGSHUAI; DING, BAIJUAN; WANG, JIE; LI, SHAN; ZHANG, YOUZHONG

    2014-01-01

    The aim of the present study was to investigate the potential effects of photodynamic therapy (PDT) mediated by the cationic porphyrin, 5,10,15,20-tetra-(N-methyl-4-pyridyl)porphine (TMPyP4), on an ovarian carcinoma cell line and the underlying mechanisms by which TMPyP4-PDT exerts its actions. The analysis of cell viability, hematoxylin and eosin staining and flow cytometric apoptosis assays revealed that TMPyP4-PDT potently suppressed the growth of the A2780 cells in a laser energy- and dose-dependent manner. Mechanically, it was observed that TMPyP4-PDT suppressed the proliferation and motility of the A2780 cells. In addition, the expression levels of minichromosome maintenance protein-2 (MCM2) and carbonic anhydrase IX (CA-IX) were detected by western blot analysis. The results indicated that the TMPyP4-PDT-induced apoptosis and antimetastatic activity in the A2780 cells was accompanied by the inhibition of the expression of MCM2 and CA-IX. Therefore, TMPyP4-PDT may represent a potential therapeutic method for the treatment of ovarian carcinoma. PMID:24959286

  16. A Novel Monoclonal Antibody Specific for Canine CD25 (P4A10): Selection and Evaluation of Canine Tregs

    PubMed Central

    Abrams, V. Kraig; Hwang, Billanna; Lesnikova, Marina; Gass, M. John; Wayner, Elizabeth; Castilla-Llorente, Cristina; Georges, George E.; Nash, Richard A.

    2010-01-01

    A monoclonal antibody (mAb), P4A10, was made to the canine interleukin-2 receptor alpha chain (IL-2R?; p55; Tac antigen; CD25) to facilitate studies of canine regulatory T-cells (Treg). By non-reduced western blot, P4A10 bound to a 55 kD protein, the expected size of IL-2R?. In flow cytometry assays, it reacted with a minor population of circulating dog CD3+CD4+ T cells and the majority (>60%) of in vitro PMA-Ionomycin (PMA-IO)-activated canine CD3+ T-cells. P4A10 recognized a hematopoietic cell population enriched for FoxP3+ cells as measured by flow cytometry. The P4A10-selected fractions of T-cells had significantly increased copy numbers of CD25, FoxP3, IL-10, and TGF? as detected by RT-PCR (reverse transcriptase PCR) compared to the negative fractions. The P4A10-selected cells inhibited 3H (tritiated) thymidine incorporation in a mixed leukocyte reaction (MLR) containing responders of the same origin. P4A10-selected T cells from fresh peripheral blood mononuclear cells had less FoxP3 (p = 0.07) by qRT-PCR (quantitative RT-PCR) and were less suppressive (p=0.01) than in vitro alloantigen-activated Treg. The mAb P4A10 is specific for canine CD25 and can be used to facilitate studies of CD25+FoxP3+ Treg in this clinically relevant large animal model. PMID:20060595

  17. Ternary phosphides Ce 3Zn 2? x P 4 and Ce 4Zn 2? x P 5 – Stacking variants of CeP 6 octahedra and ZnP 4 tetrahedra

    Microsoft Academic Search

    Hannes Lincke; Wilfried Hermes; Tom Nilges; Rainer Pöttgen

    2008-01-01

    New ternary phosphides Ce3Zn2?xP4 and Ce4Zn2?xP5 were synthesized from intermetallic precursors CeZn and CeZn3, cerium, and phosphorus in equimolar NaCl\\/KCl fluxes. The structures were refined on the basis of single crystal X-ray diffractometer data: La3Zn2P4 type, R3¯m, a=414.1(1), c=4102(1)pm, wR2=0.0378, 288 F2 values, 17 variables for Ce3Zn1.82P4 and P3¯m1, a=415.9(1), c=1710.5(6)pm, wR2=0.0408, 361 F2 values, 20 variables for Ce4Zn1.80P5 (new

  18. Serum levels of acute phase proteins: SAA, Hp and progesterone (P4) in mares with early embryonic death.

    PubMed

    Krakowski, L; Krawczyk, C H; Kostro, K; Stefaniak, T; Novotny, F; Obara, J

    2011-08-01

    The study involved 46 healthy purebred Arabian mares exhibiting regular oestrous cycles that underwent artificial insemination (AI). Pregnancy was detected ultrasonographically (US) in 40 mares. In 15 mares in foal, early embryonic death (EED) was observed during the pregnancy days 14-21. Blood for determinations of serum acute phase proteins (SAA and Hp) and progesterone (P4) was sampled 12-24 h before ovulation and the first insemination, at 12, 24, 72, 96 h and on day 7, 10, 14, 21, 35 and 55 after ovulation. The results revealed that in 25 mares without EED, the serum levels of P4, SAA and Hp were within physiological limits; in 15 mares with EED, the levels of SAA and Hp were significantly increased. In seven mares with EED, high levels of SAA and Hp were already found before ovulation and at 12, 24, 72, 96 h as well as on day 7 and 10 post-ovulation, whereas the level of P4 was normal for early pregnancy. In the remaining eight mares with EED, increased levels of SAA and Hp were found at 72 h after ovulation and maintained until day 55. In this group, the level of P4 decreased since 96 h after ovulation. Determinations of SAA, Hp and P4 in mares in early pregnancy (EP) are useful for monitoring normal development of pregnancy and for diagnosis of subclinical genital inflammations, which may lead to EED. PMID:21241377

  19. Immunotherapy with a Combination of Intravenous Immune Globulin and P4 Peptide Rescues Mice from Postinfluenza Pneumococcal Pneumonia?

    PubMed Central

    Weeks, Jenni N.; Boyd, Kelli L.; Rajam, Gowrisankar; Ades, Edwin W.; McCullers, Jonathan A.

    2011-01-01

    Alternate therapies are needed for treatment of secondary bacterial pneumonia following influenza. The immunomodulatory peptide P4 has shown promise in mouse models of primary pneumococcal infection. Mice infected with influenza virus and then challenged with Streptococcus pneumoniae were treated with a combination of P4 peptide and intravenous immune globulin. Survival was improved from 20% to 80% in treated mice relative to controls. Clinical cure correlated with increased clearance of bacteria and decreased lung consolidation. Greater trafficking of professional phagocytic cells to the site of pneumococcal infection coupled with enhanced opsonophagocytosis as manifest by decreased surface display of Fc? receptors (Fc?R) on neutrophils and macrophages were associated with P4 peptide treatment. This suggests that the mechanism of action for improved clearance of bacteria engendered by P4 is through improved uptake by phagocytes mediated by IgG Fc-Fc? receptor interactions following antibody-mediated opsonophagocytosis of bacteria. Antibody-based therapies, when coupled with immune modulators, such as P4 peptide, may be an effective tool together with antibiotics in our armamentarium against severe pneumonia. PMID:21383090

  20. Crystal Structure of Pb 5Bi 18P 4O 42: A Fluorite-Related Superstructure

    NASA Astrophysics Data System (ADS)

    Giraud, Sophie; Wignacourt, Jean-Pierre; Swinnea, Steve; Steinfink, Hugo; Harlow, Richard

    2000-05-01

    Single crystals of a new oxyphosphate of bismuth and lead, Pb5Bi18P4O42, were studied using short-wavelength synchrotron X-ray radiation. The compound is monoclinic, I2/m, a=11.885(2) Å, b=11.540(2) Å, c=15.636(3) Å, ?=90.23(3)°, Z=2. The crystal is twinned by pseudo-merohedry. The structure refinement converged to R=0.0366. There are five crystallographically independent Bi atoms. The oxygen coordination polyhedron around Bi(1) is a slightly distorted cube with Bi-O bonds varying from 2.381(11) to 2.662(10) Å. The other four Bi atoms are in a severely distorted oxygen environment with bond lengths varying from 2.102(5) to 3.16(2) Å. A greater variation of the oxygen coordination polyhedra exists around the three crystallographically independent Pb atoms changing from a somewhat elongated cube to a monocapped pentagonal bipyramid; bond distances vary from 2.13(2) to 3.38(2) Å. Of 20 crystallographically independent oxygen ions 11 are disordered. The structure consists of two Bi-O layers parallel to (101). They are interconnected perpendicular to [010] by layers consisting of Pb and PO4. The two crystallographically independent PO4 moieties are disordered. This compound displays a ?-Bi2O3 fluorite superstructure. The locations of the nonbonded lone-pair electrons were calculated and vary from 0 to 1.1 Å. These displacements from the cation nucleus are indicative of the extent of s-p hybridization, where zero displacement represents the spherical nonbonded 6s2 orbital. The extent of hybridization is a function of the distortion of the oxygen coordination polyhedron around the cation.

  1. The miR-124-Prolyl Hydroxylase P4HA1-MMP1 axis plays a critical role in prostate cancer progression

    PubMed Central

    Chakravarthi, Balabhadrapatruni V. S. K.; Cie?lik, Marcin; Zheng, Heng; Nallasivam, Sivakumar; Arekapudi, Subramanyeswara R.; Jing, Xiaojun; Siddiqui, Javed; Athanikar, Jyoti; Carskadon, Shannon L.; Lonigro, Robert J.; Kunju, Lakshmi P.; Chinnaiyan, Arul M.; Palanisamy, Nallasivam; Varambally, Sooryanarayana

    2014-01-01

    Collagen prolyl hydroxylases (C-P4HAs) are a family of enzymes involved in collagen biogenesis. One of the isoforms of P4HA, Prolyl 4-hydroxylase, alpha polypeptide I (P4HA1), catalyzes the formation of 4-hydroxyproline that is essential for the proper three-dimensional folding of newly synthesized procollagen chains. Here, we show the overexpression of P4HA1 in aggressive prostate cancer. Immunohistochemical analysis using tissue microarray demonstrated that P4HA1 expression was correlated with prostate cancer progression. Using in vitro studies, we showed that P4HA1 plays a critical role in prostate cancer cell growth and tumor progression. Expression profiling studies using P4HA1-modulated prostate cells suggested regulation of Matrix metalloprotease 1. The invasive properties of P4HA1 overexpressing cells were reversed by blocking MMP1. Our studies indicate P4HA1 copy number gain in a subset of metastatic prostate tumors and its expression is also regulated by microRNA-124. MiR-124 in turn is negatively regulated by transcriptional repressors EZH2 and CtBP1, both of which are overexpressed in aggressive prostate cancer. Chick chorioallantoic membrane (CAM) assay and mice xenograft investigations show that P4HA1 is required for tumor growth and metastasis in vivo. Our observations suggest that P4HA1 plays a critical role in prostate cancer progression and could serve as a viable therapeutic target. PMID:25115393

  2. Probing the kinetic and thermodynamic consequences of the tetraloop/tetraloop receptor monovalent ion-binding site in P4-P6 RNA by smFRET.

    PubMed

    Bisaria, Namita; Herschlag, Daniel

    2015-04-01

    Structured RNA molecules play roles in central biological processes and understanding the basic forces and features that govern RNA folding kinetics and thermodynamics can help elucidate principles that underlie biological function. Here we investigate one such feature, the specific interaction of monovalent cations with a structured RNA, the P4-P6 domain of the Tetrahymena ribozyme. We employ single molecule FRET (smFRET) approaches as these allow determination of folding equilibrium and rate constants over a wide range of stabilities and thus allow direct comparisons without the need for extrapolation. These experiments provide additional evidence for specific binding of monovalent cations, Na+ and K+, to the RNA tetraloop-tetraloop receptor (TL-TLR) tertiary motif. These ions facilitate both folding and unfolding, consistent with an ability to help order the TLR for binding and further stabilize the tertiary contact subsequent to attainment of the folding transition state. PMID:25849913

  3. P 4.72 A PRELIMINARY INVESTIGATION OF DERECHO-PRODUCING MCSs IN ENVIRONMENTS OF VERY LOW DEWPOINTS

    E-print Network

    P 4.72 A PRELIMINARY INVESTIGATION OF DERECHO-PRODUCING MCSs IN ENVIRONMENTS OF VERY LOW DEWPOINTS winds and other severe weather threats with which they are associated, derecho-producing mesoscale and summer, derecho MCSs typically occur in environments of substantial convective instability, with very

  4. NAIM and site-specific functional group modification analysis of RNase P RNA: magnesium dependent structure within the conserved P1-P4 multihelix junction contributes to catalysis.

    PubMed

    Kaye, Nicholas M; Christian, Eric L; Harris, Michael E

    2002-04-01

    The tRNA processing endonuclease ribonuclease P contains an essential and highly conserved RNA molecule (RNase P RNA) that is the catalytic subunit of the enzyme. To identify and characterize functional groups involved in RNase P RNA catalysis, we applied self-cleaving ribozyme-substrate conjugates, on the basis of the RNase P RNA from Escherichia coli, in nucleotide analogue interference mapping (NAIM) and site-specific modification experiments. At high monovalent ion concentrations (3 M) that facilitate protein-independent substrate binding, we find that the ribozyme is largely insensitive to analogue substitution and that concentrations of Mg2+ (1.25 mM) well below that necessary for optimal catalytic rate (>100 mM) are required to produce interference effects because of modification of nucleotide bases. An examination of the pH dependence of the reaction rate at 1.25 mM Mg2+ indicates that the increased sensitivity to analogue interference is not due to a change in the rate-limiting step. The nucleotide positions detected by NAIM under these conditions are located exclusively in the catalytic domain, consistent with the proposed global structure of the ribozyme, and predominantly occur within the highly conserved P1-P4 multihelix junction. Several sensitive positions in J3/4 and J2/4 are proximal to a previously identified site of divalent metal ion binding in the P1-P4 element. Kinetic analysis of ribozymes with site-specific N7-deazaadenosine and deazaguanosine modifications in J3/4 was, in general, consistent with the interference results and also permitted the analysis of sites not accessible by NAIM. These results show that, in this region only, modification of the N7 positions of A62, A65, and A66 resulted in measurable effects on reaction rate and modification at each position displayed distinct sensitivities to Mg2+ concentration. These results reveal a restricted subset of individual functional groups within the catalytic domain that are particularly important for substrate cleavage and demonstrate a close association between catalytic function and metal ion-dependent structure in the highly conserved P1-P4 multihelix junction. PMID:11926814

  5. Nqrs Data for C24H76BLiN12O4P4 (Subst. No. 1593)

    NASA Astrophysics Data System (ADS)

    Chihara, H.; Nakamura, N.

    This document is part of Subvolume B 'Substances Containing C10H16 … Zn' of Volume 48 'Nuclear Quadrupole Resonance Spectroscopy Data' of Landolt-Börnstein - Group III 'Condensed Matter'. It contains an extract of Section '3.2 Data tables' of the Chapter '3 Nuclear quadrupole resonance data' providing the NQRS data for C24H76BLiN12O4P4 (Subst. No. 1593)

  6. Ky'y(0°) for 3He(d,p)4He near the Jpi=3\\/2+ resonance

    Microsoft Academic Search

    K. A. Fletcher; C. R. Brune; B. M. Fisher; R. P. Fitzgerald; H. J. Karwowski; D. S. Leonard; E. J. Ludwig; R. C. Runkle; M. H. Wood; W. H. Geist; K. D. Veal; G. M. Hale

    2002-01-01

    The polarization transfer coefficient Ky'y(0°) has been measured for the 3He(d,p)4He reaction at energies of 520, 890, and 1490 keV. The measured values are ~-2\\/3, consistent with expectations based on the presence of a broad Jpi=3\\/2+ resonance at Ed=430 keV. A comparison with data taken at somewhat higher energies reveals a large change in this observable as the reaction becomes

  7. P4 capped amides and lactams as HCV NS3 protease inhibitors with improved potency and DMPK profile

    SciTech Connect

    Nair, Latha G.; Sannigrahi, Mousumi; Bogen, Stephane; Pinto, Patrick; Chen, Kevin X.; Prongay, Andrew; Tong, Xiao; Cheng, K.-C.; Girijavallabhann, Viyyoor; Njoroge, F. George (Merck)

    2010-09-03

    SAR studies on the extension of P3 unit of Boceprevir (1, SCH 503034) with amides and lactams and their synthesis is described. Extensive SAR studies resulted in the identification of 36 bearing 4,4-dimethyl lactam as the new P4 cap unit with improved potency (K*{sub i}, EC 90 = 70 nM) and pharmacokinetic properties (Rat AUC (PO) = 3.52 {micro}M h) compared to 1.

  8. Autioionizing states in the photionization of the 3s(2)3p(4) (3)Pe ground state of sulfur

    NASA Technical Reports Server (NTRS)

    Tayal, S. S.

    1988-01-01

    The partial and total photoionization cross sections for the S(3s/2/3p/4/ /3/Pe) ground state are calculated in both the dipole length and velocity forms. The prominent features in the cross sections are the autoionization Rydberg series converging to S+(3s/2/p/3/ /2/D/0/, /2/P/0/) excited-state thresholds. The results are pertinent to the study of sulfur in the plasma of Jupiter's satellite Io.

  9. Extending The P4P Agenda, Part 1: How Medicare Can Improve Patient Decision Making And Reduce Unnecessary Care

    PubMed Central

    Wennberg, John E.; O'Connor, Annette M.; Collins, E. Dale; Weinstein, James N.

    2008-01-01

    The decision to undergo many discretionary medical treatments should be based on informed patient choice. Shared decision making is an effective strategy for achieving this goal. The Centers for Medicare and Medicaid Services (CMS) should extend its pay-for-performance (P4P) agenda to assure that all Americans have access to a certified shared decision-making process. This paper outlines a strategy to achieve informed patient choice as the standard of practice for preference-sensitive care. PMID:17978377

  10. Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization

    PubMed Central

    Clarke, Jonathan H.; Irvine, Robin F.

    2013-01-01

    Mammals have genes coding for three PI5P4Ks (PtdIns5P 4-kinases), and these have different cellular localizations, tissue distributions and lipid kinase activities. We describe in the present paper a detailed molecular exploration of human PI5P4Ks ?, ? and ?, as well as their fly and worm homologues, to understand how and why these differences came to be. The intrinsic ATPase activities of the three isoforms are very similar, and we show that differences in their G-loop regions can account for much of their wide differences in lipid kinase activity. We have also undertaken an extensive in silico evolutionary study of the PI5P4K family, and show experimentally that the single PI5P4K homologues from Caenorhabditis elegans and Drosophila melanogaster are as widely different in activity as the most divergent mammalian isoforms. Finally we show that the close association of PI5P4Ks ? and ? is a true heterodimerization, and not a higher oligomer association of homodimers. We reveal that structural modelling is consistent with this and with the apparently random heterodimerization that we had earlier observed between PI5P4K? and PI5P4K? [Wang, Bond, Letcher, Richardson, Lilley, Irvine and Clarke (2010), Biochem. J. 430, 215–221]. Overall the molecular diversity of mammalian PI5P4Ks explains much of their properties and behaviour, but their physiological functionality remains elusive. PMID:23758345

  11. New high-pressure polymorph of In2S3 with defect Th3P4-type structure

    NASA Astrophysics Data System (ADS)

    Lai, Xiaojing; Zhu, Feng; Wu, Ye; Huang, Rong; Wu, Xiang; Zhang, Qian; Yang, Ke; Qin, Shan

    2014-02-01

    The high pressure behavior of ?-In2S3 (I41/amd and Z=16) has been studied by in situ synchrotron radiation X-ray diffraction combined with diamond anvil cell up to 71.7 GPa. Three pressure-induced phase transitions are evidenced at ~6.6 GPa, ~11.1 GPa at room temperature and 35.6 GPa after the high-temperature annealing using a portable laser heating system. The new polymorph of In2S3 at 35.6 GPa is assigned to the denser cubic defect Th3P4 structure (I4bar3d and Z=5.333), whose unit-cell parameters are a=7.557(1) Å and V=431.6(2) Å3. The Th3P4-type phase can be stable at least up to 71.7 GPa and cannot be preserved at ambient pressure. The pressure-volume relationship is well described by the second-order Birch-Murnaghan Equation of State, which yields B0=63(3) GPa and B0?=4 (fixed) for the ?-In2S3 phase and B0=87(3) GPa and B0?=4 (fixed) for the defect Th3P4-type phase respectively.

  12. P4 medicine: how systems medicine will transform the healthcare sector and society

    PubMed Central

    Glusman, Gustavo; Brogaard, Kristin; Price, Nathan D; Hood, Leroy

    2014-01-01

    Ten years ago, the proposition that healthcare is evolving from reactive disease care to care that is predictive, preventive, personalized and participatory was regarded as highly speculative. Today, the core elements of that vision are widely accepted and have been articulated in a series of recent reports by the US Institute of Medicine. Systems approaches to biology and medicine are now beginning to provide patients, consumers and physicians with personalized information about each individual’s unique health experience of both health and disease at the molecular, cellular and organ levels. This information will make disease care radically more cost effective by personalizing care to each person’s unique biology and by treating the causes rather than the symptoms of disease. It will also provide the basis for concrete action by consumers to improve their health as they observe the impact of lifestyle decisions. Working together in digitally powered familial and affinity networks, consumers will be able to reduce the incidence of the complex chronic diseases that currently account for 75% of disease-care costs in the USA. PMID:25342952

  13. WARM SPITZER PHOTOMETRY OF THREE HOT JUPITERS: HAT-P-3b, HAT-P-4b AND HAT-P-12b

    E-print Network

    Todorov, Kamen O.

    We present Warm Spitzer/IRAC secondary eclipse time series photometry of three short-period transiting exoplanets, HAT-P-3b, HAT-P-4b and HAT-P-12b, in both the available 3.6 and 4.5 ?m bands. HAT-P-3b and HAT-P-4b are ...

  14. The function of phosphatidylinositol 5-phosphate 4-kinase ? (PI5P4K?) explored using a specific inhibitor that targets the PI5P binding site

    E-print Network

    Clarke, Jonathan H.; Giudici, Maria-Luisa; Burke, John E.; Williams, Roger L.; Maloney, David J.; Marugan, Juan; Irvine, Robin F.

    2014-12-11

    : Phosphatidylinositol 5-phosphate 4-kinase ? inhibition Corresponding author, R.F. Irvine rfi20@cam.ac.uk Phone 44-1223-334177 FAX 44- 1223 334040 Keywords: Phosphatidylinositol 5-phosphate; phosphatidylinositol 5-phosphate 4- kinase ?; PI5P; PI5P4K; PI5P4K?...

  15. Phase characterization, thermal stability, high-temperature transport properties, and electronic structure of rare-earth Zintl phosphides Eu3M2P4 (M = Ga, In).

    PubMed

    Yi, Tanghong; Zhang, Gaigong; Tsujii, Naohito; Fleurial, Jean-Pierre; Zevalkink, Alex; Snyder, G Jeffrey; Grønbech-Jensen, Niels; Kauzlarich, Susan M

    2013-04-01

    Two rare-earth-containing ternary phosphides, Eu3Ga2P4 and Eu3In2P4, were synthesized by a two-step solid-state method with stoichiometric amounts of the constitutional elements. Refinements of the powder X-ray diffraction are consistent with the reported single-crystal structure with space group C2/c for Eu3Ga2P4 and Pnnm for Eu3In2P4. Thermal gravimetry and differential scanning calorimetry (TG-DSC) measurements reveal high thermal stability up to 1273 K. Thermal diffusivity measurements from room temperature to 800 K demonstrate thermal conductivity as low as 0.6 W/m·K for both compounds. Seebeck coefficient measurements from room temperature to 800 K indicate that both compounds are small band gap semiconductors. Eu3Ga2P4 shows p-type conductivity and Eu3In2P4 p-type conductivity in the temperature range 300-700 K and n-type conductivity above 700 K. Electronic structure calculations result in band gaps of 0.60 and 0.29 eV for Eu3Ga2P4 and Eu3In2P4, respectively. As expected for a valence precise Zintl phase, electrical resistivity is large, approximately 2600 and 560 m?·cm for Eu3Ga2P4 and Eu3In2P4 at room temperature, respectively. Measurements of transport properties suggest that these Zintl phosphides have potential for being good high-temperature thermoelectric materials with optimization of the charge carrier concentration by appropriate extrinsic dopants. PMID:23517094

  16. Action of p-(4-amidino-phenoxy)-benzaldehyde-p-amidino-phenylhydrazone dihydrochloride on Leishmania donovani infections in the golden hamster.

    PubMed

    Raether, W; Seidenath, H; Loewe, H

    1978-12-01

    The chemotherapeutic effect of a new diamidine, HOE 668, the p-(4-amidino-phenoxy)-benzaldehyde-p-amidino-phenylhydrazone dihydrochloride, was compared with that of known anti-leishmanial drugs in golden hamsters infected with Leishmania donovani. The effect of HOE 668 against visceral leishmaniasis proved superior to that of pentamidine isethionate and the pentavalent antimonial drugs, sodium stibogluconate and N-methylglucamine antimoniate. However, HOE 668 can be used only experimentally because of its toxicity. Its very good anti-leishmanial action qualifies HOE 668 as a standard compound in screening tests. PMID:216324

  17. Formation of sub-7 nm feature size PS-b-P4VP block copolymer structures by solvent vapour process

    NASA Astrophysics Data System (ADS)

    Chaudhari, Atul; Ghoshal, Tandra; Shaw, Matthew T.; Cummins, Cian; Borah, Dipu; Holmes, Justin D.; Morris, Michael A.

    2014-03-01

    The nanometer range structure produced by thin films of diblock copolymers makes them a great of interest as templates for the microelectronics industry. We investigated the effect of annealing solvents and/or mixture of the solvents in case of symmetric Poly (styrene-block-4vinylpyridine) (PS-b-P4VP) diblock copolymer to get the desired line patterns. In this paper, we used different molecular weights PS-b-P4VP to demonstrate the scalability of such high ? BCP system which requires precise fine-tuning of interfacial energies achieved by surface treatment and that improves the wetting property, ordering, and minimizes defect densities. Bare Silicon Substrates were also modified with polystyrene brush and ethylene glycol self-assembled monolayer in a simple quick reproducible way. Also, a novel and simple in situ hard mask technique was used to generate sub-7nm Iron oxide nanowires with a high aspect ratio on Silicon substrate, which can be used to develop silicon nanowires post pattern transfer.

  18. Production of high energy and low flux protons using 2D(3He,p)4He for space detector calibrations

    NASA Astrophysics Data System (ADS)

    Wang, Y. Q.; Burward-Hoy, J. M.; Tesmer, J. R.

    2014-08-01

    In this report, we want to demonstrate that besides the conventional use for elemental analysis and depth profiling by ion beam analysis (IBA), particles generated through ion-solid interactions in IBA may find other novel and important applications. Specifically, we use Rutherford backscattered and nuclear reaction produced high energy proton particles to calibrate an energetic particle subsystem (called ZEP) of the Space and Atmospheric Burst Reporting System (SABRS) at Los Alamos National Laboratory (LANL). To simulate low radiation flux in the space, we have devised an experiment that uses an ultrathin (?51.8 nm) self-support gold foil to scatter a proton beam from a 3 MV Tandem accelerator into the ZEP subsystem. Direct backscattering from the thin gold foil produces proton particles with tunable energies of 0.2-6.0 MeV and desired counting rates of <10 kHz. To extend the proton particle energy beyond the Tandem's limit of 6 MeV, a high Q-value nuclear reaction, 2D + 3He ? p + 4He + 18.352 MeV, was used. This reaction allows us to obtain as high as 25.6 MeV proton particles on our 3 MV tandem accelerator, more than 4 times as high as the accelerator's maximum proton beam energy, and has greatly extended our proton energy range for this calibration activity. Preliminary ZEP subsystem calibration results are presented.

  19. Identification of a specific lns(l,3,4,5)P4-binding protein as a member of the GAP1 family

    Microsoft Academic Search

    Peter J. Cullen; J. Justin Hsuan; Oanh Truong; Andrew J. Letcher; Trevor R. Jackson; Alan P. Dawson; Robin F. Irvine

    1995-01-01

    INOSITOL 1,3,4,5-tetrakisphosphate (Ins(l,3,4,5)P4) is produced rapidly from inositol 1,4,5-trisphosphate (Ins(l,4,5)P3) in stimulated cells1,2. Despite extensive experimentation, no clearly defined cellular function has yet been described for this inositol phosphate. Binding sites specific for Ins(l,3,4,5)P4 have been identified in several tissues3,4, and we have purified one such protein to homogeneity5. Its high affinity for Ins(l,3,4,5)P4, and its exquisite specificity for this

  20. Activation of prophage P4 by the P2 Cox protein and the sites of action of the Cox protein on the two phage genomes.

    PubMed Central

    Saha, S; Haggård-Ljungquist, E; Nordström, K

    1989-01-01

    Phage P2 induces the unrelated prophage P4. In this paper we show that this is due to the activation of the P4 late promoter PII by the P2 Cox protein. This is in contrast to the effects of Cox on P2, for which it is known from previous work that it acts as a repressor of the promoter Pc, which is responsible for expression of the immunity repressor C. The activator role of Cox was revealed by its effect on replication of P4 DNA and on the formation of chloramphenicol acetyltransferase when a promoterless cat gene was inserted downstream of the P4 PII promoter. DNase I protection studies revealed that the Cox protein binds to the repressor promoter Pc of phage P2 and to the promoter PII of phage P4. In the latter case the Cox protein binds upstream of the -35 region, in analogy to several other activators of promoters. A weak binding was found in the promoters Pe of phage P2 and Ple of phage P4. The Cox protein is a case of viral transactivation of the replication genes of one phage by a control protein of the other. However, the effects of the Cox protein are totally different in the two phages, repressive in one case and activating in the other. Images PMID:2657731

  1. Cloning and expression of diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase from Lupinus angustifolius L.

    PubMed Central

    Maksel, D; Guranowski, A; Ilgoutz, S C; Moir, A; Blackburn, M G; Gayler, K R

    1998-01-01

    The first isolation, cloning and expression of cDNA encoding an asymmetric diadenosine 5',5'''P1,P4-tetraphosphate pyrophosphohydrolase (Ap4A hydrolase) from a higher plant is described. Ap4A hydrolase protein was purified from seeds of both Lupinus luteus and Lupinus angustifolius and partially sequenced. The Ap4A hydrolase cDNA was cloned from L. angustifolius cotyledonary polyadenylated RNA using reverse transcription and PCR with primers based on the amino acid sequence. The cDNA encoded a protein of 199 amino acids, molecular mass 22982Da. When expressed in Escherichia coli fused to a maltose-binding protein, the enzyme catalysed asymmetric cleavage of Ap4A to AMP and ATP which was inhibited at concentrations of F- as low as 3 microM. These are properties characteristic of Ap4A hydrolase (asymmetrical) (EC 3.6.1. 17). Comparison of the Ap4A hydrolase sequences derived from the four known cDNAs from pig, human, lupin and fission yeast showed that, like the mammalian hydrolase, the lupin enzyme possesses a Mut T motif but no other significant similarities. No sequence similarity to the human fragile histidine triad protein, as found in the Ap4A hydrolase from Schizosaccharomyces pombe, was detected in the Ap4A hydrolase from lupin. PMID:9425114

  2. Measurement of the plasma astrophysical S factor for the 3He(D, p)4He reaction in exploding molecular clusters

    E-print Network

    M. Barbui; W. Bang; A. Bonasera; K. Hagel; K. Schmidt; J. B. Natowitz; R. Burch; G. Giuliani; M. Barbarino; H. Zheng; G. Dyer; H. J. Quevedo; E. Gaul; A. C. Bernstein; M. Donovan; S. Kimura; M. Mazzocco; F. Consoli; R. De Angelis; P. Andreoli; T. Ditmire

    2013-07-01

    The plasma astrophysical S factor for the 3He(D, p)4He fusion reaction was measured for the first time at temperatures of few keV, using the interaction of intense ultrafast laser pulses with molecular deuterium clusters mixed with 3He atoms. Different proportions of D2 and 3He or CD4 and 3He were mixed in the gas jet target in order to allow the measurement of the cross-section for the 3He(D, p)4He reaction. The yield of 14.7 MeV protons from the 3He(D, p)4He reaction was measured in order to extract the astrophysical S factor at low energies. Our result is in agreement with other S factor parameterizations found in the literature.

  3. Effect of MHC haplotype on immune response upon experimental SHIVSF162P4cy infection of Mauritian cynomolgus macaques.

    PubMed

    Borsetti, Alessandra; Ferrantelli, Flavia; Maggiorella, Maria T; Sernicola, Leonardo; Bellino, Stefania; Gallinaro, Alessandra; Farcomeni, Stefania; Mee, Edward T; Rose, Nicola J; Cafaro, Aurelio; Titti, Fausto; Ensoli, Barbara

    2014-01-01

    Little is known about the effects of Major Histocompatibility Complex (MHC) haplotypes on immunity to primate lentiviruses involving both acquired and innate immune responses. We present statistical evidence of the influence of MHC polymorphism on antiviral immunity of Mauritian cynomolgus macaques (MCM) following simian/human immunodeficiency virus SHIVSF162P4cy infection, involving the production of pro- and anti-inflammatory cytokines and ?-defensins, which may modulate acquired immune responses. During the acute phase of infection, IL-10 correlated positively with viral load and negatively with CD4+T cell counts. Furthermore, ?-defensins production was directly correlated with plasma viral RNA, particularly at peak of viral load. When the effects of the MHC were analyzed, a significant association between lower anti-Env binding and neutralizing antibody levels with class IB M4 haplotype and with class IA, IB M4 haplotype, respectively, was observed in the post-acute phase. Lower antibody responses may have resulted into a poor control of infection thus explaining the previously reported lower CD4 T cell counts in these monkeys. Class II M3 haplotype displayed significantly lower acute and post-acute IL-10 levels. In addition, significantly lower levels of ?-defensins were detected in class IA M3 haplotype monkeys than in non-M3 macaques, in the post-acute phase of infection. These data indicate that the MHC could contribute to the delicate balance of pro-inflammatory mechanisms, particularly with regard to the association between IL-10 and ?-defensins in lentivirus infection. Our results show that host genetic background, virological and immunological parameters should be considered for the design and interpretation of HIV-1 vaccine efficacy studies. PMID:24695530

  4. Effect of MHC Haplotype on Immune Response upon Experimental SHIVSF162P4cy Infection of Mauritian Cynomolgus Macaques

    PubMed Central

    Borsetti, Alessandra; Ferrantelli, Flavia; Maggiorella, Maria T.; Sernicola, Leonardo; Bellino, Stefania; Gallinaro, Alessandra; Farcomeni, Stefania; Mee, Edward T.; Rose, Nicola J.; Cafaro, Aurelio; Titti, Fausto; Ensoli, Barbara

    2014-01-01

    Little is known about the effects of Major Histocompatibility Complex (MHC) haplotypes on immunity to primate lentiviruses involving both acquired and innate immune responses. We present statistical evidence of the influence of MHC polymorphism on antiviral immunity of Mauritian cynomolgus macaques (MCM) following simian/human immunodeficiency virus SHIVSF162P4cy infection, involving the production of pro- and anti-inflammatory cytokines and ?-defensins, which may modulate acquired immune responses. During the acute phase of infection, IL-10 correlated positively with viral load and negatively with CD4+T cell counts. Furthermore, ?-defensins production was directly correlated with plasma viral RNA, particularly at peak of viral load. When the effects of the MHC were analyzed, a significant association between lower anti-Env binding and neutralizing antibody levels with class IB M4 haplotype and with class IA, IB M4 haplotype, respectively, was observed in the post-acute phase. Lower antibody responses may have resulted into a poor control of infection thus explaining the previously reported lower CD4 T cell counts in these monkeys. Class II M3 haplotype displayed significantly lower acute and post-acute IL-10 levels. In addition, significantly lower levels of ?-defensins were detected in class IA M3 haplotype monkeys than in non-M3 macaques, in the post-acute phase of infection. These data indicate that the MHC could contribute to the delicate balance of pro-inflammatory mechanisms, particularly with regard to the association between IL-10 and ?-defensins in lentivirus infection. Our results show that host genetic background, virological and immunological parameters should be considered for the design and interpretation of HIV-1 vaccine efficacy studies. PMID:24695530

  5. 5530 J. Phys. Chem. 1988, 92, 5530-5540 Dynamics of the Reaction O(3P) 4-HBr: Experimental Investigation and Theoretical

    E-print Network

    Zare, Richard N.

    reaction heavy +light-heavy -heavy-light + heavy. Evidence was found for a contribution from reaction5530 J. Phys. Chem. 1988, 92, 5530-5540 Dynamics of the Reaction O(3P) 4- HBr: Experimental:December 28, 1987; In Final Form: February 23, 1988) The reaction O(3P)+HBr -OH(X211)+ Br has been

  6. When incentives work too well: locally implemented pay for performance (P4P) and adverse sanctions towards home birth in Tanzania - a qualitative study

    PubMed Central

    2014-01-01

    Background Despite limited evidence of its effectiveness, performance-based payments (P4P) are seen by leading policymakers as a potential solution to the slow progress in reaching Millennium Development Goal 5: improved maternal health. This paper offers insights into two of the aspects that are lacking in the current literature on P4P, namely what strategies health workers employ to reach set targets, and how the intervention plays out when implemented by local government as part of a national programme that does not receive donor funding. Methods A total of 28 in-depth interviews (IDIs) with 25 individuals were conducted in Mvomero district over a period of 15 months in 2010 and 2011, both before and after P4P payments. Seven facilities, including six dispensaries and one health centre, were covered. Informants included 17 nurses, three clinical officers, two medical attendants, one lab technician and two district health administrators. Results Health workers reported a number of strategies to increase the number of deliveries at their facility, including health education and cooperation with traditional health providers. The staff at all facilities also reported that they had told the women that they would be sanctioned if they gave birth at home, such as being fined or denied clinical cards and/or vaccinations for their babies. There is a great uncertainty in relation to the potential health impacts of the behavioural changes that have come with P4P, as the reported strategies may increase the numbers, but not necessarily the quality. Contrary to the design of the P4P programme, payments were not based on performance. We argue that this was due in part to a lack of resources within the District Administration, and in part as a result of egalitarian fairness principles. Conclusions Our results suggest that particular attention should be paid to adverse effects when using external rewards for improved health outcomes, and secondly, that P4P may take on a different form when implemented by local implementers without the assistance of professional P4P specialists. PMID:24438556

  7. Above-threshold ionization near the 3p4d {sup 1}F{sup o} autoionizing state in magnesium

    SciTech Connect

    Reber, A.; Baynard, T.; Berry, R.S. [Department of Chemistry and The James Franck Institute, University of Chicago, Chicago, Illinois 60637 (United States); Martin, F. [Departamento de Quimica C-9, Universidad Autonoma de Madrid, 28049 Madrid (Spain); Bachau, H. [Centre des Lasers Intenses et Applications, UMR 5107 du CNRS-CEA-Universite de Bordeaux 1, 351 Cours de la Liberation, F-33405 Talence (France)

    2005-05-15

    Two-photon above-threshold ionization (ATI) relative cross sections from the 3 {sup 1}P state of Mg have been measured using two-color ionization in the focus of a magnetic bottle spectrometer and have been calculated using the Green's-function method in the Feshbach formalism and an L{sup 2}-integrable close-coupling approach, with a basis of L{sup 2}-integrable B-spline functions. We report these cross sections in the region of 3d4p {sup 1}F{sup o} autoionizing state, with photon energies of 3.3-3.6 eV. This is one of the few direct comparisons between ab initio theory and experiments in ATI in the vicinity of a Feshbach resonance. A good agreement between theory and experiment is found in the relative total cross sections.

  8. Short communication: can the mammopathogenic Escherichia coli P4 strain have a direct role on the caseinolysis of milk observed during bovine mastitis?

    PubMed

    Dufour, D; Jameh, N; Dary, A; Le Roux, Y

    2009-04-01

    During bacterial bovine mastitis, the quality of milk is altered because of caseinolysis. Endogenous potential actors in milk responsible for this caseinolysis have been well studied, unlike the exogenous bacterial ones. The aim of this study was to evaluate the direct role in caseinolysis of a mammopathogenic strain, Escherichia coli P4. Secretion of at least 4 extracellular bacterial caseinolytic enzymes was highlighted by zymography, in 3 different growth media, and at each bacterial growth state, suggesting that their expression was constitutive. Different experimental conditions to evaluate caseinolytic potential did not show any significant caseinolytic activity of E. coli P4 and of the 4 extracellular proteases detected, suggesting that the high caseinolysis observed during E. coli bovine mastitis does result from endogenous milk actors. PMID:19307620

  9. FALL 2011 -DRAFT 6 4/21/2011 Rev 12:02 A4/P4 Period Monday Tuesday Wednesday Thursday Friday

    E-print Network

    Wang, Yuqing

    695 Frazer 702 11:30 301 Hammer 703 673C J Taylor 544 301 Hammer 703 673C J Taylor 544 301 Hammer 703 673C J Taylor 54412:00-1:15 101 Jahren 723 12:00-1:15 101 Jahren 723 12:30 621 Hellebrand 613 250FALL 2011 - DRAFT 6 4/21/2011 Rev 12:02 A4/P4 Period Monday Tuesday Wednesday Thursday Friday 8

  10. Reduction in Rotavirus Disease and Sustained Predominance of G2P[4] Rotavirus Strain following Introduction of Rotavirus Vaccine in Recife, Brazil.

    PubMed

    Montenegro, Fernanda Maria Ulisses; Falbo, Ana Rodrigues; Germano, Eliane Mendes; Correia, Nancy Barros; Souza, Edvaldo da Silva; Nakagomi, Osamu; Nakagomi, Toyoko; Cuevas, Luis E; Cunliffe, Nigel A; Correia, Jailson B

    2015-06-01

    Rotavirus vaccination was introduced in Brazil in March 2006. We describe the distribution of rotavirus genotypes in children with acute gastroenteritis in a hospital in Recife, Brazil, during pre- and post-vaccination periods. There was a 43.8% reduction in the proportion of diarrhea episodes due to rotavirus. Nevertheless, we observed a sustained predominance of G2P[4] as the main genotype identified in the post-vaccination period. PMID:25724210

  11. Influence of MHC class I and II haplotypes on the experimental infection of Mauritian cynomolgus macaques with SHIVSF162P4cy.

    PubMed

    Borsetti, A; Maggiorella, M T; Sernicola, L; Bellino, S; Ferrantelli, F; Belli, R; Fulgenzi, D; Mee, E T; Rose, N J; Cafaro, A; Ensoli, B; Titti, F

    2012-07-01

    Mauritian cynomolgus macaques (MCM) are widely used in human immunodeficiency virus research because of their restricted major histocompatibility complex (MHC) diversity which provides the opportunity to address the influence of host factors on vaccine studies. We herein report the impact of MHC haplotype on the outcome of 21 MCM infections with the CCR5-tropic simian/human immunodeficiency virus (SHIV)(SF162P4cy). MCM were susceptible to SHIV(SF162P4cy) infection as shown by viremia and loss of CD4+ T cells. A significant association between haplotype M7 (class IA, IB, II) and persistent viremia was observed in chronic phase, whereas recombinant class IA haplotype was associated with a reduction of viral RNA during acute infection. Class IB M4 haplotype displayed significantly lower acute phase provirus copy numbers. In addition, statistical analysis indicated a detrimental effect of haplotype M4 (class IA, IB) on the course of infection as indicated by lower CD4+ T-cell levels during chronic infection. A decrease in post-acute phase CD4+ T-cell numbers was also observed in haplotype M2 animals. This is the first report that documents the effects of host MHC class I and II molecules on the SHIV(SF162P4cy) infection in MCM, particularly with regard to the association between recombinant class IA, M4, and M7 haplotypes and the dynamic of viral replication and level of CD4+ T cells. PMID:22494179

  12. Direct imaging of structural heterogeneity of the melt-spun Fe85.2Si2B8P4Cu0.8 alloy

    NASA Astrophysics Data System (ADS)

    Sato, Kazuhisa; Takenaka, Kana; Makino, Akihiro; Hirotsu, Yoshihiko

    2015-06-01

    A structural heterogeneity of the melt-spun Fe85.2Si2B8P4Cu0.8 alloy has been studied by spherical aberration (Cs) corrected high-resolution transmission electron microscopy. Hollow-cone illumination imaging revealed that the density of coherent scattering regions in the as-quenched Fe85.2Si2B8P4Cu0.8 alloy is much higher than that in the Fe76Si9B10P5 bulk metallic glass. According to the Cs-corrected TEM, crystalline atomic clusters, typically of ˜1 nm in diameter, are densely distributed in an amorphous matrix of Fe85.2Si2B8P4Cu0.8 alloy. Observation of four-fold and six-fold atomic arrangements of these clusters implies existence of Fe clusters with the body centered cubic structure. These Fe clusters must be responsible for the formation of ultrahigh-density ?-Fe nanocrystals produced by post-annealing.

  13. TGF?1 evokes myoblast apoptotic response via a novel signaling pathway involving S1P4 transactivation upstream of Rho-kinase-2 activation.

    PubMed

    Cencetti, Francesca; Bernacchioni, Caterina; Tonelli, Francesca; Roberts, Edward; Donati, Chiara; Bruni, Paola

    2013-11-01

    In view of its multiple detrimental effects, transforming growth factor ?1 (TGF?1) is recognized as critical negative regulator of skeletal muscle repair. Apoptosis of skeletal muscle precursor cells driven by TGF?1 contributes to the negative role exerted by the cytokine in tissue repair, although the underlying molecular mechanisms are still elusive. Herein we report the identification of a new signaling pathway, relying on Rho kinase-2 stimulation, subsequent to SMAD-dependent S1P4 up-regulation and transactivation via sphingosine kinase (SK)-2, that accounts for TGF?1-induced apoptosis in cultured myoblasts. S1P4-specific gene silencing reduced by almost 50% activation of caspase-3 and poly-ADP ribosyl transferase cleavage elicited by TGF?1. Moreover, the selective S1P4 antagonist CYM50358 also reduced the TGF?1 proapoptotic effects. By employing pharmacological and molecular biological approaches, the involvement of SK2 and ROCK2 in the transmission of the TGF?1 apoptotic action was also demonstrated. These results reinforce the notion that the SK/S1P axis plays a fundamental role in TGF?1 mode of action in skeletal muscle cells and, by disclosing a novel mechanism by which TGF?1 exerts its harmful action, pinpoint new molecular targets that in principle could be beneficial in the treatment of several skeletal muscle disorders or aging-dependent muscle atrophy. PMID:23913862

  14. Aligned silicon nanofins via the directed self-assembly of PS-b-P4VP block copolymer and metal oxide enhanced pattern transfer.

    PubMed

    Cummins, Cian; Gangnaik, Anushka; Kelly, Roisin A; Borah, Dipu; O'Connell, John; Petkov, Nikolay; Georgiev, Yordan M; Holmes, Justin D; Morris, Michael A

    2015-04-21

    'Directing' block copolymer (BCP) patterns is a possible option for future semiconductor device patterning, but pattern transfer of BCP masks is somewhat hindered by the inherently low etch contrast between blocks. Here, we demonstrate a 'fab' friendly methodology for forming well-registered and aligned silicon (Si) nanofins following pattern transfer of robust metal oxide nanowire masks through the directed self-assembly (DSA) of BCPs. A cylindrical forming poly(styrene)-block-poly(4-vinyl-pyridine) (PS-b-P4VP) BCP was employed producing 'fingerprint' line patterns over macroscopic areas following solvent vapor annealing treatment. The directed assembly of PS-b-P4VP line patterns was enabled by electron-beam lithographically defined hydrogen silsequioxane (HSQ) gratings. We developed metal oxide nanowire features using PS-b-P4VP structures which facilitated high quality pattern transfer to the underlying Si substrate. This work highlights the precision at which long range ordered ?10 nm Si nanofin features with 32 nm pitch can be defined using a cylindrical BCP system for nanolithography application. The results show promise for future nanocircuitry fabrication to access sub-16 nm critical dimensions using cylindrical systems as surface interfaces are easier to tailor than lamellar systems. Additionally, the work helps to demonstrate the extension of these methods to a 'high ?' BCP beyond the size limitations of the more well-studied PS-b-poly(methyl methylacrylate) (PS-b-PMMA) system. PMID:25798892

  15. 99mTc-3P4-RGD2 Scintimammography in the Assessment of Breast Lesions: Comparative Study with 99mTc-MIBI

    PubMed Central

    Gao, Shi; Ji, Tiefeng; Wen, Qiang; Song, Yan; Zhu, Lei; Xu, Zheli; Liu, Lin

    2014-01-01

    Purpose To compare the potential application of 99mTc-3P-Arg-Gly-Asp (99mTc-3P4-RGD2) scintimammography (SMM) and 99mTc-methoxyisobutylisonitrile (99mTc-MIBI) SMM for the differentiation of malignant from benign breast lesions. Method Thirty-six patients with breast masses on physical examination and/or suspicious mammography results that required fine needle aspiration cytology biopsy (FNAB) were included in the study. 99mTc-3P4-RGD2 and 99mTc-MIBI SMM were performed with single photon emission computed tomography (SPECT) at 60 min and 20 min respectively after intravenous injection of 738±86 MBq radiotracers on a separate day. Images were evaluated by the tumor to non-tumor localization ratios (T/NT). Receiver operating characteristic (ROC) curve analysis was performed on each radiotracer to calculate the cut-off values of quantitative indices and to compare the diagnostic performance for the ability to differentiate malignant from benign diseases. Results The mean T/NT ratio of 99mTc-3P4-RGD2 in malignant lesions was significantly higher than that in benign lesions (3.54±1.51 vs. 1.83±0.98, p<0.001). The sensitivity, specificity, and accuracy of 99mTc-3P4-RGD2 SMM were 89.3%, 90.9% and 89.7%, respectively, with a T/NT cut-off value of 2.40. The mean T/NT ratio of 99mTc-MIBI in malignant lesions was also significantly higher than that in benign lesions (2.86±0.99 vs. 1.51±0.61, p<0.001). The sensitivity, specificity and accuracy of 99mTc-MIBI SMM were 87.5%, 72.7% and 82.1%, respectively, with a T/NT cut-off value of 1.45. According to the ROC analysis, the area under the curve for 99mTc-3P4-RGD2 SMM (area?=?0.851) was higher than that for 99mTc-MIBI SMM (area?=?0.781), but the statistical difference was not significant. Conclusion 99mTc-3P4-RGD2 SMM does not provide any significant advantage over the established 99mTc-MIBI SMM for the detection of primary breast cancer. The T/NT ratio of 99mTc-3P4-RGD2 SMM was significantly higher than that of 99mTc-MIBI SMM. Both tracers could offer an alternative method for elucidating non-diagnostic mammograms. PMID:25250628

  16. Magnetic Field Alignment of PS-P4VP: a Non-Liquid Crystalline Coil-Coil Block Copolymer

    NASA Astrophysics Data System (ADS)

    Rokhlenko, Yekaterina; Zhang, Kai; Larson, Steven; Gopalan, Padma; O'Hern, Corey; Osuji, Chinedum

    2015-03-01

    Magnetic fields provide the ability to control alignment of self-assembled soft materials such as block copolymers. Most prior work in this area has relied on the presence of ordered assemblies of anisotropic liquid crystalline species to ensure sufficient magnetic anisotropy to drive alignment. Recent experiments with poly(styrene-b-4-vinylpyridine), a non-liquid crystalline BCP, however, show field-induced alignment of a lamellar microstructure during cooling across the order-disorder transition. Using in situ x-ray scattering, we examine the roles of field strength and cooling rate on the alignment response of this low MW coil-coil BCP. Alignment is first observed at field strengths as low as 1 Tesla and improves markedly with both increasing field strength and slower cooling. We present a geometric argument to illustrate the origin of a finite, non-trivial magnetic susceptibility anisotropy for highly stretched surface-tethered polymer chains and corroborate this using coarse-grained molecular dynamics simulations. We rationalize the magnetic field response of the system in terms of the mobility afforded by the absence of entanglements, the intrinsic anisotropy resulting from the stretched polymer chains and sterically constrained conjugated rings, and the large grain size in these low molecular weight materials.

  17. NF-Y controls transcription of the minute virus of mice P4 promoter through interaction with an unusual binding site.

    PubMed Central

    Gu, Z; Plaza, S; Perros, M; Cziepluch, C; Rommelaere, J; Cornelis, J J

    1995-01-01

    Electrophoretic mobility shift assays performed with nuclear extracts from human fibroblasts revealed the formation of two major protein complexes with an oligonucleotide (nucleotides 78 to 107) from the palindromic region located upstream from the minute virus of mice (MVM) P4 promoter. It was shown that this oligonucleotide bound USF at the enhancer E box CACATG. The second complex contained the transcription factor NF-Y, whose association was surprising because its target sequence lacks the canonical CCAAT motif present in all mammalian NF-Y binding sites identified so far. The MVM NF-Y recognition element instead contains the CCAAC sequence. USF and NF-Y had distinct but overlapping sequence requirements for binding, suggesting that their associations with MVM DNA were mutually exclusive. Because of the palindromic nature of MVM DNA terminal sequences, NF-Y associated with the three nucleotide configurations corresponding to the hairpin structure and to the external and internal arms of the extended duplex replication form, respectively. However, owing to the imperfection of the palindrome, the binding of USF was restricted to the internal arm. Point mutations that suppressed the in vitro binding of NF-Y to the internal palindromic arm reduced the activity of the resident P4 promoter, while those preventing complex formation with USF did not, as determined by transient expression assays using the luciferase reporter gene. The data led to the identification of a novel P4 upstream regulatory region capable of interacting with two transcription factors, from which one (NF-Y) appeared to upmodulate the activity of the promoter. PMID:7983715

  18. Production of Ins(1,3,4,5)P4 mediated by the kinase Itpkb inhibits store-operated calcium channels and regulates B cell selection and activation

    Microsoft Academic Search

    Andrew T Miller; Mark Sandberg; Yina H Huang; Michael Young; Susan Sutton; Karsten Sauer; Michael P Cooke

    2007-01-01

    Antigen receptor–mediated production of inositol-1,4,5-trisphosphate (Ins(1,4,5)P3) in lymphocytes triggers the release of Ca2+ from intracellular stores; this release of Ca2+ results in the opening of store-operated Ca2+ channels in the plasma membrane. Here we report that mice lacking Ins(1,4,5)P3 3-kinase B (Itpkb), which converts Ins(1,4,5)P3 to inositol-1,3,4,5-tetrakisphosphate (Ins(1,3,4,5)P4), had impaired B lymphocyte development and defective immunoglobulin G3 antibody responses to

  19. WARM SPITZER PHOTOMETRY OF THREE HOT JUPITERS: HAT-P-3b, HAT-P-4b AND HAT-P-12b

    SciTech Connect

    Todorov, Kamen O. [Department of Astronomy and Astrophysics, Pennsylvania State University, University Park, PA 16802 (United States); Deming, Drake [Department of Astronomy, University of Maryland at College Park, College Park, MD 20742 (United States); Knutson, Heather A. [Division of Geological and Planetary Sciences, California Institute of Technology, Pasadena, CA 91125 (United States); Burrows, Adam [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States); Fortney, Jonathan J.; Laughlin, Gregory [Department of Astronomy and Astrophysics, University of California at Santa Cruz, Santa Cruz, CA 95064 (United States); Lewis, Nikole K. [Department of Earth, Atmospheric, and Planetary Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Cowan, Nicolas B. [Department of Physics and Astronomy, Northwestern University, Evanston, IL 60208 (United States); Agol, Eric [Department of Astronomy, University of Washington, Box 351580, Seattle, WA 98195 (United States); Desert, Jean-Michel [Astronomy Department, California Institute of Technology, Pasadena, CA 91125 (United States); Sada, Pedro V. [Department of Physics and Mathematics, University of Monterrey, Monterrey (Mexico); Charbonneau, David [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA 02138 (United States); Langton, Jonathan [Department of Physics, Principia College, Elsah, IL 62028 (United States); Showman, Adam P. [Lunar and Planetary Laboratory, University of Arizona, Tucson, AZ 85721 (United States)

    2013-06-20

    We present Warm Spitzer/IRAC secondary eclipse time series photometry of three short-period transiting exoplanets, HAT-P-3b, HAT-P-4b and HAT-P-12b, in both the available 3.6 and 4.5 {mu}m bands. HAT-P-3b and HAT-P-4b are Jupiter-mass objects orbiting an early K and an early G dwarf star, respectively. For HAT-P-3b we find eclipse depths of 0.112%+0.015%-0.030% (3.6 micron) and 0.094%+0.016%-0.009% (4.5 {mu}m). The HAT-P-4b values are 0.142%+0.014%-0.016% (3.6 micron) and 0.122%+0.012%-0.014% 4.5 {mu}m). The two planets' photometry is consistent with inefficient heat redistribution from their day to night sides (and low albedos), but it is inconclusive about possible temperature inversions in their atmospheres. HAT-P-12b is a Saturn-mass planet and is one of the coolest planets ever observed during secondary eclipse, along with the hot Neptune GJ 436b and the hot Saturn WASP-29b. We are able to place 3{sigma} upper limits on the secondary eclipse depth of HAT-P-12b in both wavelengths: <0.042% (3.6 {mu}m) and <0.085% (4.5 {mu}m). We discuss these results in the context of the Spitzer secondary eclipse measurements of GJ 436b and WASP-29b. It is possible that we do not detect the eclipses of HAT-P-12b due to high eccentricity, but find that weak planetary emission in these wavelengths is a more likely explanation. We place 3{sigma} upper limits on the |e cos {omega}| quantity (where e is eccentricity and {omega} is the argument of periapsis) for HAT-P-3b (<0.0081) and HAT-P-4b (<0.0042), based on the secondary eclipse timings.

  20. Inhibitors of hepatitis C virus NS3.4A protease. Effect of P4 capping groups on inhibitory potency and pharmacokinetics.

    PubMed

    Perni, Robert B; Chandorkar, Gurudatt; Cottrell, Kevin M; Gates, Cynthia A; Lin, Chao; Lin, Kai; Luong, Yu-Ping; Maxwell, John P; Murcko, Mark A; Pitlik, Janos; Rao, Govinda; Schairer, Wayne C; Van Drie, John; Wei, Yunyi

    2007-06-15

    Reversible tetrapeptide-based compounds have been shown to effectively inhibit the hepatitis C virus NS3.4A protease. Inhibition of viral replicon RNA production in Huh-7 cells has also been demonstrated. We show herein that the inclusion of hydrogen bond donors on the P4 capping group of tetrapeptide-based inhibitors result in increased binding potency to the NS3.4A protease. The capping groups also impart significant effects on the pharmacokinetic profile of these inhibitors. PMID:17482818

  1. Loss of the Arabidopsis thaliana P4-ATPase ALA3 Reduces Adaptability to Temperature Stresses and Impairs Vegetative, Pollen, and Ovule Development

    PubMed Central

    McDowell, Stephen C.; López-Marqués, Rosa L.; Poulsen, Lisbeth R.; Palmgren, Michael G.; Harper, Jeffrey F.

    2013-01-01

    Members of the P4 subfamily of P-type ATPases are thought to help create asymmetry in lipid bilayers by flipping specific lipids between the leaflets of a membrane. This asymmetry is believed to be central to the formation of vesicles in the secretory and endocytic pathways. In Arabidopsis thaliana, a P4-ATPase associated with the trans-Golgi network (ALA3) was previously reported to be important for vegetative growth and reproductive success. Here we show that multiple phenotypes for ala3 knockouts are sensitive to growth conditions. For example, ala3 rosette size was observed to be dependent upon both temperature and soil, and varied between 40% and 80% that of wild-type under different conditions. We also demonstrate that ala3 mutants have reduced fecundity resulting from a combination of decreased ovule production and pollen tube growth defects. In-vitro pollen tube growth assays showed that ala3 pollen germinated ?2 h slower than wild-type and had approximately 2-fold reductions in both maximal growth rate and overall length. In genetic crosses under conditions of hot days and cold nights, pollen fitness was reduced by at least 90-fold; from ?18% transmission efficiency (unstressed) to less than 0.2% (stressed). Together, these results support a model in which ALA3 functions to modify endomembranes in multiple cell types, enabling structural changes, or signaling functions that are critical in plants for normal development and adaptation to varied growth environments. PMID:23667493

  2. Molecular Epidemiology of Contemporary G2P[4] Human Rotaviruses Cocirculating in a Single U.S. Community: Footprints of a Globally Transitioning Genotype

    PubMed Central

    Dennis, Allison F.; McDonald, Sarah M.; Payne, Daniel C.; Mijatovic-Rustempasic, Slavica; Esona, Mathew D.; Edwards, Kathryn M.; Chappell, James D.

    2014-01-01

    ABSTRACT Group A rotaviruses (RVs) remain a leading cause of childhood gastroenteritis worldwide. Although the G/P types of locally circulating RVs can vary from year to year and differ depending upon geographical location, those with G1P[8], G2P[4], G3P[8], G4P[8], G9P[8], and G12P[8] specificities typically dominate. Little is known about the evolution and diversity of G2P[4] RVs and the possible role that widespread vaccine use has had on their increased frequency of detection. To address these issues, we analyzed the 12 G2P[4] RV isolates associated with a rise in RV gastroenteritis cases at Vanderbilt University Medical Center (VUMC) during the 2010-2011 winter season. Full-genome sequencing revealed that the isolates had genotype 2 constellations typical of DS-1-like viruses (G2P[4]-I2-R2-C2-M2-A2-N2-T2-E2-H2). Phylogenetic analyses showed that the genome segments of the isolates were comprised of two or three different subgenotype alleles; this enabled recognition of three distinct clades of G2P[4] viruses that caused disease at VUMC in the 2010-2011 season. Although the three clades cocirculated in the same community, there was no evidence of interclade reassortment. Bayesian analysis of 328 VP7 genes of G2 viruses isolated in the last 39 years indicate that existing G2 VP7 gene lineages continue to evolve and that novel lineages, as represented by the VUMC isolates, are constantly being formed. Moreover, G2 lineages are characteristically shaped by lineage turnover events that introduce new globally dominant strains every 7 years, on average. The ongoing evolution of G2 VP7 lineages may give rise to antigenic changes that undermine vaccine effectiveness in the long term. IMPORTANCE Little is known about the diversity of cocirculating G2 rotaviruses and how their evolution may undermine the effectiveness of rotavirus vaccines. To expand our understanding of the potential genetic range exhibited by rotaviruses circulating in postvaccine communities, we analyzed part of a collection of rotaviruses recovered from pediatric patients in the United States from 2010 to 2011. Examining the genetic makeup of these viruses revealed they represented three segregated groups that did not exchange genetic material. The distinction between these three groups may be explained by three separate introductions. By comparing a specific gene, namely, VP7, of the recent rotavirus isolates to those from a collection recovered from U.S. children between 1974 and 1991 and other globally circulating rotaviruses, we were able to reconstruct the timing of events that shaped their ancestry. This analysis indicates that G2 rotaviruses are continuously evolving, accumulating changes in their genetic material as they infect new patients. PMID:24429371

  3. Electron Excitation Cross Sections for the C II Transitions 2s(exp 2)2p P-2(exp 0) yields 2s2p(exp 2) P-4, D-2, and S-2

    NASA Technical Reports Server (NTRS)

    Smith, Steven J.; Zuo, M.; Chutjian, A.; Tayal, S. S.; Williams, I. D.

    1996-01-01

    Experimental and theoretical excitation cross sections are reported for the transitions 2s(exp 2) 2p-2(exp 0) yield 2s2p(exp 2)P-4, D-2, and S-2 in C II. The transition wavelengths (energies) are 2324 A (5.34 eV), 1335 x (9.29 eV), and 1036 A (11.97 eV), respectively. Use is made of electron energy-loss and merged beams methods. The energy range covered is from below each threshold (4 - 11 eV) to 15-24 eV. As in previous work with O II, care was taken to assess and minimize the metastable fraction in the C II beam, to account for contributions from nearby energy-loss features, and to collect the full angular range of inelastically scattered electrons. A comparison is made for each transition between experiment and new 8-state R-matrix calculations. Subject headings: atomic data ultraviolet: general

  4. Nano-crystallization and magnetic mechanisms of Fe85Si2B8P4Cu1 amorphous alloy by ab initio molecular dynamics simulation

    NASA Astrophysics Data System (ADS)

    Wang, Yaocen; Takeuchi, Akira; Makino, Akihiro; Liang, Yunye; Kawazoe, Yoshiyuki

    2014-05-01

    Iron-based amorphous and nano-crystalline alloys have attracted a growing interest due to their potential in the application of magnetic coil production. However, fundamental understanding of the nano-crystallization mechanisms and magnetic features in the amorphous structure are still lack of knowledge. In the present work, we performed ab initio molecular dynamics simulation to clarify the ionic and electronic structure in atomic scale, and to derive the origin of the good magnetic property of Fe85Si2B8P4Cu1 amorphous alloy. The simulation gave a direct evidence of the Cu-P bonding preference in the amorphous alloy, which may promote nucleation in nano-crystallization process. On the other hand, the electron transfer and the band/orbital features in the amorphous alloy suggests that alloying elements with large electronegativity and the potential to expand Fe disordered matrix are preferred for enhancing the magnetization.

  5. Ab initio many-body calculations of the (3)H(d,n)(4)He and (3)He(d,p)(4)He fusion reactions.

    PubMed

    Navrátil, Petr; Quaglioni, Sofia

    2012-01-27

    We apply the ab initio no-core shell model combined with the resonating-group method approach to calculate the cross sections of the (3)H(d,n)(4)He and (3)He(d,p)(4)He fusion reactions. These are important reactions for the big bang nucleosynthesis and the future of energy generation on Earth. Starting from a selected similarity-transformed chiral nucleon-nucleon interaction that accurately describes two-nucleon data, we performed many-body calculations that predict the S factor of both reactions. Virtual three-body breakup effects are obtained by including excited pseudostates of the deuteron in the calculation. Our results are in satisfactory agreement with experimental data and pave the way for microscopic investigations of polarization and electron-screening effects, of the (3)H(d,?n)(4)He bremsstrahlung and other reactions relevant to fusion research. PMID:22400830

  6. Purification and functional characterization of diadenosine 5',5?-P(1),P(4)-tetraphosphate phosphorylases from Mycobacterium smegmatis and Mycobacterium avium.

    PubMed

    Honda, Naoko; Kim, Hyun; Rimbara, Emiko; Kato, Atsushi; Shibayama, Keigo; Mori, Shigetarou

    2015-08-01

    We recently demonstrated that the Rv2613c protein from Mycobacterium tuberculosis H37Rv is a novel diadenosine 5',5?-P(1),P(4)-tetraphosphate (Ap4A) phosphorylase (MtAPA) that forms a tetramer. Mycobacterium avium and Mycobacterium smegmatis express proteins named MAV_3489 and MSMEG_2932, respectively, that are homologous to MtAPA. Here we showed that the MAV_3489 and MSMEG_2932 proteins possess Ap4A phosphorylase activity and enzymatic properties similar to those of MtAPA. Furthermore, gel-filtration column chromatography revealed that MAV_3489 and MSMEG_2932 assembled into homotetramers in solution, indicating that they may also form unique Ap4A-binding sites composed of tetramers. PMID:25940844

  7. 3D Modeling of Dengue Virus NS4B and Chikungunya Virus nsP4: Identification of a Common Drug Target and Designing a Single Antiviral Inhibitor.

    PubMed

    Satheesh, Garisekurthi; Prabhu, Nagu P; Venkataramana, Musturi

    2014-01-01

    Dengue and chikungunya virus infections are one of the major causes of morbidity and mortality in tropical and sub-tropical regions of the world. These two viruses belong to two different families with many similarities and dissimilarities. Both are enveloped viruses and the mode of transmission is also by the same mosquito species. Especially in case of symptom expression, there is confusion between these two viruses. Reports indicate the overlapping endemic areas and co-infections of both viruses in a single patient. The above factors indicate that there is a need for developing a single drug/vaccine for both the viruses. As a first report in this direction, we have used the bioinformatics tools to identify a common target in both the viruses for a single inhibitor molecule. Phylogenetic and distance based analyses using the nucleotide sequences of arthropod and non-arthropod borne viruses indicated a common origin of evolutionary point for mosquito borne viruses, irrespective of their families. Similarly, the amino acid sequences of non-structural protein-4B (NS4B) of dengue virus and non-structural protein-P4 (nsP4) of chikungunya virus showed a common evolutionary origin. Modeled and superimposed 3D-structures of above two proteins showed a common alpha helix. Virtual screening of selected molecules was done to identify the molecules which can bind to the identified common helix and found that N-(p-tolylmethyl)-3-[(3-pyridylmethylamino)methyl]benzamide (TPB) has significant binding characteristics to the common helix. Molecular simulations indicated that both the protein-TPB complexes were stable. Therefore, we propose that TPB or its analogues could act as antiviral agents against both the viruses. PMID:25847003

  8. Alcohol LOX Steam Generator Test Experience

    NASA Astrophysics Data System (ADS)

    Schaefer, K.; Dommers, M.

    2004-10-01

    At the DLR test centre in Lampoldshausen there is a long experience in the development of rocket steam generators as a main subsystem for the altitude simulation. The rocket steam generators make it possible to supply the required quantities of steam at short notice with reduced investment and operating costs. The rocket steam generators are based on the combustion of liquid oxygen (LOX) and ethyl alcohol (ALC). The paper deals with the experience of the development of the steam generators and the operation at the altitude simulation P1.0 for satellite propulsion and P4.2 for altitude simulation of AESTUS upper stage engine.

  9. Introduction Experiments

    E-print Network

    Escolano, Francisco

    Introduction Method Experiments Conclusions EBEM An Entropy-based EM Algorithm for Gaussian Mixture;Introduction Method Experiments Conclusions Outline 1 Introduction 2 Method Shannon entropy estimation Splitting a Kernel 3 Experiments Synthetic Data Experiments Image Data Experiments 4 Conclusions A

  10. Introduction Experiments

    E-print Network

    Escolano, Francisco

    Introduction Method Experiments Conclusions A New Feasible Approach to Multi-dimensional Scale;Introduction Method Experiments Conclusions Outline 1 Introduction 2 Method 3 Experiments 4 Conclusions P. Suau Experiments Conclusions Outline 1 Introduction 2 Method 3 Experiments 4 Conclusions P. Suau and F. Escolano

  11. The P4-P2? Amino Acids Surrounding Human Norovirus Polyprotein Cleavage Sites Define the Core Sequence Regulating Self-Processing Order

    PubMed Central

    May, Jared; Viswanathan, Prasanth; Ng, Kenneth K.-S.; Medvedev, Alexei

    2014-01-01

    ABSTRACT Noroviruses (NoV) are members of the family Caliciviridae. The human NoV open reading frame 1 (ORF1) encodes a 200-kDa polyprotein which is cleaved by the viral 20-kDa 3C-like protease (Pro, NS6) into 6 nonstructural proteins that are necessary for viral replication. The NoV ORF1 polyprotein is processed in a specific order, with “early” sites (NS1/2-3 and NS3-4) being cleaved rapidly and three “late” sites (NS4-5, NS5-6, and NS6-7) processed subsequently and less efficiently. Previously, we demonstrated that the NoV polyprotein processing order is directly correlated with the efficiency of the enzyme, which is regulated by the primary amino acid sequences surrounding ORF1 cleavage sites. Using fluorescence resonance energy transfer (FRET) peptides representing the NS2-3 and NS6-7 ORF1 cleavage sites, we now demonstrate that the amino acids spanning positions P4 to P2? (P4-P2?) surrounding each site comprise the core sequence controlling NoV protease enzyme efficiency. Furthermore, the NoV polyprotein self-processing order can be altered by interchanging this core sequence between NS2-3 and any of the three late sites in in vitro transcription-translation assays. We also demonstrate that the nature of the side chain at the P3 position for the NS1/2-3 (Nterm/NTPase) site confers significant influence on enzyme catalysis (kcat and kcat/Km), a feature overlooked in previous structural studies. Molecular modeling provides possible explanations for the P3 interactions with NoV protease. IMPORTANCE Noroviruses (NoV) are the prevailing cause of nonbacterial acute gastroenteritis worldwide and pose a significant financial burden on health care systems. Proteolytic processing of the viral nonstructural polyprotein is required for norovirus replication. Previously, the core sequence of amino acids surrounding the scissile bonds responsible for governing the relative processing order had not been determined. Using both FRET-based peptides and full-length NoV polyprotein, we have successfully demonstrated that the core sequences spanning positions P4-P2? surrounding the NS2-3, NS4-5, NS5-6, and NS6-7 cleavage sites contain all of the structural information necessary to control processing order. We also provide insight into a previously overlooked role for the NS2-3 P3 residue in enzyme efficiency. This article builds upon our previous studies on NoV protease enzymatic activities and polyprotein processing order. Our work provides significant additional insight into understanding viral polyprotein processing and has important implications for improving the design of inhibitors targeting the NoV protease. PMID:24991013

  12. Introduction Experiments

    E-print Network

    Escolano, Francisco

    Introduction Method Experiments Conclusions Robot Navigation Behaviors based on Omnidirectional WAF 2007 #12;Introduction Method Experiments Conclusions Outline 1 Introduction 2 Method Direction Estimation Approach Entropy estimation Entropy approximation Experiments OV-sonars Gradient threshold

  13. Anomalous high amplitude ratios of P5KP/PKPab and P4KP/P(S)cP observed globally around 1 Hz

    NASA Astrophysics Data System (ADS)

    Ivan, Marian; Wang, Rongjiang

    2013-04-01

    Amplitude ratio of 30 short-period conspicuous P5KP and PKPab phases from five intermediate depth or deep events in Fiji-Tonga recorded at European stations around 150° distance shows a mean value two to three times the ratio of the synthetic amplitudes obtained by the normal-mode theory (and ak135 model) or by full-wave theory (and PREM). There is a large variance in the results, also observed in five amplitude ratios from one event in Argentina observed at temporary stations in China around 156°. Global recordings of three major deep earthquakes in Fiji, Bonin, and Western Brazil observed at ASAR, WRA, and ZRNK arrays, at 59 North America stations and at six South Pole stations displayed conspicuous P4KP and PcP (or ScP) phases. The amplitude ratio values of P4KP vs P(S)cP are sometimes almost one order of magnitude larger than the corresponding values of the synthetics. In both cases, arrival times and slowness values (corrected for ellipticity and station elevation) at the distances up to 23° beyond the A cutoff point predicted by ray theory match both the synthetics, suggesting the observations are the AB branch of PmKP ( m = 4, 5) around 1 Hz. In disagreement to ray theory, no reliable BC branch is observed neither on the recordings nor on the normal-mode synthetics. The high amplitude ratio values cannot be explained by realistic perturbations of the velocity or attenuation values of the global models in the proximity of the core-to-mantle boundary (CMB). We speculate that the focusing effects and/or strong scattering most likely associated to some anomalous velocity areas of the lowermost mantle are responsible for that. The results suggest limitations of the previous evaluations of the short-period attenuation in the outer core from PmKP amplitudes ( m ? 3), irrespective of the fact that they are obtained by using ray theory, normal-mode or full-wave synthetics. Attempts to use PmKP arrival times in order to refine velocity structure in the proximity of CMB should be also regarded with care if the propagation times have been computed with ray theory.

  14. Molecular Dynamic Simulation to Explore the Molecular Basis of Btk-PH Domain Interaction with Ins(1,3,4,5)P4

    PubMed Central

    Lu, Dan; Jiang, Junfeng; Liang, Zhongjie; Sun, Maomin; Luo, Cheng; Shen, Bairong

    2013-01-01

    Bruton's tyrosine kinase contains a pleckstrin homology domain, and it specifically binds inositol 1,3,4,5-tetrakisphosphate (Ins(1,3,4,5)P4), which is involved in the maturation of B cells. In this paper, we studied 12 systems including the wild type and 11 mutants, K12R, S14F, K19E, R28C/H, E41K, L11P, F25S, Y40N, and K12R-R28C/H, to investigate any change in the ligand binding site of each mutant. Molecular dynamics simulations combined with the method of molecular mechanics/Poisson-Boltzmann solvent-accessible surface area have been applied to the twelve systems, and reasonable mutant structures and their binding free energies have been obtained as criteria in the final classification. As a result, five structures, K12R, K19E, R28C/H, and E41K mutants, were classified as “functional mutations,” whereas L11P, S14F, F25S, and Y40N were grouped into “folding mutations.” This rigorous study of the binding affinity of each of the mutants and their classification provides some new insights into the biological function of the Btk-PH domain and related mutation-causing diseases. PMID:24307874

  15. Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo.

    PubMed

    Rathore, Abhay P S; Haystead, Timothy; Das, Pratyush K; Merits, Andres; Ng, Mah-Lee; Vasudevan, Subhash G

    2014-03-01

    The global emergence of Chikungunya virus (CHIKV) infection is alarming and currently there is no licensed vaccine or antiviral treatment available to mitigate this disease. CHIKV infection typically results in high viral load with an outcome of high fever, skin rashes, muscle pain, and sequelae of prolonged arthritis, which occurs in >90% of the infected cases. In this study, using biochemical pull-downs, mass-spectrometry, and microscopic imaging techniques, we have identified novel interactions between CHIKV nsP3 or nsP4 proteins with the host stress-pathway chaperone HSP-90 protein. Indeed, silencing of HSP-90 transcripts using siRNA disrupts CHIKV replication in cultured cells. Furthermore, drugs targeting HSP-90, such as commercially available geldanamycin, as well as other specific HSP-90 inhibitor drugs that had been obtained from a purinome mining approach (HS-10 and SNX-2112) showed dramatic reduction in viral titers and reduced inflammation in a CHIKV mouse model of severe infection and musculopathy. The detailed study of the underlying molecular mechanism of these viral and host protein interactions may provide a platform to develop novel therapeutics against CHIKV infection. PMID:24388965

  16. Fabrication of C-doped WO3 nanoparticle cluster arrays from PS-b-P4VP for room temperature H2 sensing.

    PubMed

    Liu, Shu-Juan; Yuan, Ye; Zheng, Sheng-Liang; Zhang, Jing-Huai; Wang, You

    2015-07-01

    C-doped WO3 based room temperature hydrogen sensors including nanoparticle cluster arrays and nanorods were successfully prepared by a PS-b-P4VP template based method. AFM, TEM and XPS are used to characterize the structure and composition of the samples. Analyses indicate that the C-doped WO3 nanoparticle cluster arrays are arranged in a beautiful hexagonal configuration and they are interconnected by a superthin carbon film. The cluster with sizes in the range of 12-15 nm is composed of several 4-6 nm nanocrystallites. An improved room temperature hydrogen response is found on C doped WO3 nanoparticle cluster arrays, whose response sensitivity (S), response time and recovery time are 114, 162 s and 108 s, respectively. Three aspects are used to analyze the reasons for the improved room temperature hydrogen response; the study indicates the great potential of the block copolymer based method to prepare excellent WO3 based room temperature H2 sensors. PMID:26014520

  17. Reducing Lattice Thermal Conductivity of the Thermoelectric Compound AgSbTe2 (P4/mmm) by Lanthanum Substitution: Computational and Experimental Approaches

    NASA Astrophysics Data System (ADS)

    Amouyal, Yaron

    2014-10-01

    In this study we performed lattice dynamics first-principles calculations for the promising thermoelectric (TE) compound AgSbTe2, and estimated the stability of its three polymorphs over a wide temperature range from 0 to 600 K. We calculated the vibrational density of states of the AgSbTe2 (P4/mmm) phase. The results suggested that formation of substitutional defects at Ag-sublattice sites impedes lattice vibrations, thereby reducing lattice thermal conductivity. We focused on calculations based on the Debye approximation for the compound La0.125Ag0.875SbTe2, and predicted reduction of the average sound velocity from 1684 to 1563 m s-1 as a result of La doping. This is manifested as a ca. 14% reduction in thermal conductivity. To confirm the results from computation we produced two Ag-Sb-Te-based alloys, a ternary alloy without La addition and a quaternary alloy containing La. We measured the thermal conductivity of both alloys by use of the laser flash analysis method, and, as a result of La alloying, observed a reduction in thermal conductivity from 0.92 to 0.71 W m-1 K-1 at 573 K, as calculated from first principles.

  18. CASL L1 Milestone report : CASL.P4.01, sensitivity and uncertainty analysis for CIPS with VIPRE-W and BOA.

    SciTech Connect

    Sung, Yixing (Westinghouse Electric Company LLC, Cranberry Township, PA); Adams, Brian M.; Secker, Jeffrey R. (Westinghouse Electric Company LLC, Cranberry Township, PA)

    2011-12-01

    The CASL Level 1 Milestone CASL.P4.01, successfully completed in December 2011, aimed to 'conduct, using methodologies integrated into VERA, a detailed sensitivity analysis and uncertainty quantification of a crud-relevant problem with baseline VERA capabilities (ANC/VIPRE-W/BOA).' The VUQ focus area led this effort, in partnership with AMA, and with support from VRI. DAKOTA was coupled to existing VIPRE-W thermal-hydraulics and BOA crud/boron deposit simulations representing a pressurized water reactor (PWR) that previously experienced crud-induced power shift (CIPS). This work supports understanding of CIPS by exploring the sensitivity and uncertainty in BOA outputs with respect to uncertain operating and model parameters. This report summarizes work coupling the software tools, characterizing uncertainties, and analyzing the results of iterative sensitivity and uncertainty studies. These studies focused on sensitivity and uncertainty of CIPS indicators calculated by the current version of the BOA code used in the industry. Challenges with this kind of analysis are identified to inform follow-on research goals and VERA development targeting crud-related challenge problems.

  19. Phase structures of the black D$p$-D$(p + 4)$-brane system in various ensembles II: electrical and thermodynamic stability

    E-print Network

    Zhiguang Xiao; Da Zhou

    2015-07-08

    By incorporating the electrical stability condition into the discussion, we continue the study on the thermodynamic phase structures of the D$p$-D$(p + 4)$ black brane in GG, GC, CG, CC ensembles defined in our previous paper arXiv:1502.00261. We find that including the electrical stability conditions in addition to the thermal stability conditions does not modify the phase structure of the GG ensemble but puts more constraints on the parameter space where black branes can stably exist in GC, CG, CC ensembles. In particular, the van der Waals-like phase structure which was supposed to be present in these ensembles when only thermal stability condition is considered would no longer be visible, since the phase of the small black brane is unstable under electrical fluctuations. However, the symmetry of the phase structure by interchanging the two kinds of brane charges and potentials is still preserved, which is argued to be the result of T-duality.

  20. Phase structures of the black D$p$-D$(p + 4)$-brane system in various ensembles II: electrical and thermodynamic stability

    E-print Network

    Xiao, Zhiguang

    2015-01-01

    By incorporating the electrical stability condition into the discussion, we continue the study on the thermodynamic phase structures of the D$p$-D$(p + 4)$ black brane in GG, GC, CG, CC ensembles defined in our previous paper arXiv:1502.00261. We find that including the electrical stability conditions in addition to the thermal stability conditions does not modify the phase structure of the GG ensemble but puts more constraints on the parameter space where black branes can stably exist in GC, CG, CC ensembles. In particular, the van der Waals-like phase structure which was supposed to be present in these ensembles when only thermal stability condition is considered would no longer be visible, since the phase of the small black brane is unstable under electrical fluctuations. However, the symmetry of the phase structure by interchanging the two kinds of brane charges and potentials is still preserved, which is argued to be the result of T-duality.

  1. Uridine 5'-polyphosphates (p4U and p5U) and uridine(5')polyphospho(5')nucleosides (Up(n)Ns) can be synthesized by UTP:glucose-1-phosphate uridylyltransferase from Saccharomyces cerevisiae.

    PubMed

    Guranowski, Andrzej; de Diego, Anabel; Sillero, Antonio; Günther Sillero, María Antonia

    2004-03-12

    UTP:glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Saccharomyces cerevisiae can transfer the uridylyl moiety from UDP-glucose onto tripolyphosphate (P(3)), tetrapolyphosphate (P(4)), nucleoside triphosphates (p(3)Ns) and nucleoside 5'-polyphosphates (p(4)Ns) forming uridine 5'-tetraphosphate (p(4)U), uridine 5'-pentaphosphate (p(5)U) and dinucleotides, such as Ap(4)U, Cp(4)U, Gp(4)U, Up(4)U, Ap(5)U and Gp(5)U. Unlike UDP-glucose, UDP-galactose was not a UMP donor and ADP was not a UMP acceptor. This is the first example of an enzyme that may be responsible for accumulation of dinucleoside tetraphosphates containing two pyrimidine nucleosides in vivo. Occurrence of such dinucleotides in S. cerevisiae and Escherichia coli has been previously reported (Coste et al., J. Biol. Chem. 262 (1987) 12096-12103). PMID:15013755

  2. Experience matters 1 Experience matters

    E-print Network

    Nelson, Jonathan D.

    of these theories best describes human information search. Experiment 1, which used natural sampling and experienceExperience matters 1 Experience matters: Information acquisition optimizes probability gain Jonathan D. Nelson Max Planck Institute for Human Development Craig R. M. McKenzie University of California

  3. Identification of chlorophyll ( with application of IRS-P4 OCM data and Geographical Information System - a case study of part of Bay of Bengal, India

    NASA Astrophysics Data System (ADS)

    Pavan Dayaker, T.

    2002-05-01

    As 60 - 70 % of the world's population live within 20 - 30 km of the coastline, coastal zone management and optimisation of ocean resources have grown in of importance. The study of the ocean encompasses its physical chemical, biological properties and its interaction with land and biological productivity. Mapping of coastal zone gives us insight about how to conserve its eco-balance and implement effective coastal zone management. Effective Coastal Zone Management will need accurate and comprehensive scientific data, on which decisions can be based. In the present study Ocean Color Monitor ( OCM ) data is used for identification of chlorophyll, which inturn indicates the presence of phytoplankton, which is the primary producer in the food chain, and also to fish . The study area is part of Bay of Bengal Sea near the coastal region of Andhra Pradesh, India. Remote sensing in optical region is found useful in understanding the spatial distribution of ocean water constituents, in which phytoplankton pigment which impart a green colour to the sea water, has a definite response in the visible region, which enables plant material to be distinguished from the other suspended matter. Normalised Differential Vegetative Index ( NDVI ), which is mainly used on land applications for the identification of vegetation based on chlorophyll absorption, is used on water surface in the present study. The positive value of NDVI is an indication of the presence of pigment concentration / chlorophyll / phytoplankton / fish. The successful launch of the IRS - P4 satellite which provides us a challenging opportunity to study ocean resources and its characteristics and see how best we can benefit, over a period of time, in several areas of human survival specifically related to food security on a sustained basis. This study is first of its kind in utilising the latest technology to explore the marine resources for mapping the fishing zones and the results, clearly indicate that NDVI can be utilised as an indicator for the presence of phytoplankton on water surface.

  4. The PN2-3 domain of centrosomal P4.1-associated protein implements a novel mechanism for tubulin sequestration.

    PubMed

    Cormier, Anthony; Clément, Marie-Jeanne; Knossow, Marcel; Lachkar, Sylvie; Savarin, Philippe; Toma, Flavio; Sobel, André; Gigant, Benoît; Curmi, Patrick A

    2009-03-13

    Microtubules are cytoskeletal components involved in multiple cell functions such as mitosis, motility, or intracellular traffic. In vivo, these polymers made of alphabeta-tubulin nucleate mostly from the centrosome to establish the interphasic microtubule network or, during mitosis, the mitotic spindle. Centrosomal P4.1-associated protein (CPAP; also named CENPJ) is a centrosomal protein involved in the assembly of centrioles and important for the centrosome function. This protein contains a microtubule-destabilizing region referred to as PN2-3. Here we decrypt the microtubule destabilization activity of PN2-3 at the molecular level and show that it results from the sequestration of tubulin by PN2-3 in a non-polymerizable 1:1 complex. We also map the tubulin/PN2-3 interaction both on the PN2-3 sequence and on the tubulin surface. NMR and CD data on free PN2-3 in solution show that this is an intrinsically unstructured protein that comprises a 23-amino acid residue alpha-helix. This helix is embedded in a 76-residue region that interacts strongly with tubulin. The interference of PN2-3 with well characterized tubulin properties, namely GTPase activity, nucleotide exchange, vinblastine-induced self-assembly, and stathmin family protein binding, highlights the beta subunit surface located at the intermolecular longitudinal interface when tubulin is embedded in a microtubule as a tubulin/PN2-3 interaction area. These findings characterize the PN2-3 fragment of CPAP as a protein with an unprecedented tubulin sequestering mechanism distinct from that of stathmin family proteins. PMID:19131341

  5. The green alga Scenedesmus obliquus contains both diadenosine 5',5'''-P1,P4-tetraphosphate (asymmetrical) pyrophosphohydrolase and phosphorylase activities.

    PubMed Central

    McLennan, A G; Mayers, E; Hankin, S; Thorne, N M; Prescott, M; Powls, R

    1994-01-01

    Diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) phosphorylase and Ap4A pyrophosphohydrolase activities have been purified from extracts of the green alga Scenedesmus obliquus. Both activities were also detected in Scenedesmus brasiliensis, Scenedesmus quadricauda and in Chlorella vulgaris. This is the first time that both types of enzyme have been detected in the same species. The Ap4A phosphorylase has a molecular mass of 46-48 kDa, a broad pH optimum between 7.5 and 9.5, and requires a divalent ion for activity (Mg2+ > Co2+ > Ca2+ = Mn2+ = Cd2+ > Zn2+). It degrades substrates with at least four phosphate groups and always produces a nucleoside 5'-diphosphate product. The Km values for Ap4A and Pi are 5.3 microM and 160 microM, respectively, and kcat. = 1.8 s-1. Arsenate, vanadate, molybdate, chromate and tungstate can substitute for phosphate. The enzyme also catalyses Ap4A synthesis (Keq. = [Ap4A] [Pi]/[ATP][ADP] = 9 x 10(-4)) and ADP arsenolysis. The Ap4A hydrolase has a molecular mass of 26-28 kDa, an alkaline pH optimum of 8.8-9.8, and prefers Zn2+ as the stimulatory ion (Zn2+ > Mg2+ > Mn2+ > Co2+ > Cd2+). It degrades substrates with at least four phosphate groups, having a slight preference for Ap5A, and always produces a nucleoside 5'-triphosphate product. The Km value for Ap4A is 6.6 microM and kcat. = 1.3 s-1. It is inhibited competitively by adenosine 5'-tetraphosphate (Ki = 0.67 microM) and non-competitively by fluoride (Ki = 150 microM). A 50-54 kDa dinucleoside 5',5'''-P1,P3-triphosphate (Ap3A) pyrophosphohydrolase was also detected in S. obliquus, S. quadricauda and C. vulgaris. The corresponding enzyme in S. brasiliensis (> 100 kDa) may be a dimer Images Figure 2 PMID:8198532

  6. Loss of the Arabidopsis thaliana P4-ATPases ALA6 and ALA7 impairs pollen fitness and alters the pollen tube plasma membrane.

    PubMed

    McDowell, Stephen C; López-Marqués, Rosa L; Cohen, Taylor; Brown, Elizabeth; Rosenberg, Alexa; Palmgren, Michael G; Harper, Jeffrey F

    2015-01-01

    Members of the P4 subfamily of P-type ATPases are thought to create and maintain lipid asymmetry in biological membranes by flipping specific lipids between membrane leaflets. In Arabidopsis, 7 of the 12 Aminophospholipid ATPase (ALA) family members are expressed in pollen. Here we show that double knockout of ALA6 and ALA7 (ala6/7) results in siliques with a ~2-fold reduction in seed set with a high frequency of empty seed positions near the bottom. Seed set was reduced to near zero when plants were grown under a hot/cold temperature stress. Reciprocal crosses indicate that the ala6/7 reproductive deficiencies are due to a defect related to pollen transmission. In-vitro growth assays provide evidence that ala6/7 pollen tubes are short and slow, with ~2-fold reductions in both maximal growth rate and overall length relative to wild-type. Outcrosses show that when ala6/7 pollen are in competition with wild-type pollen, they have a near 0% success rate in fertilizing ovules near the bottom of the pistil, consistent with ala6/7 pollen having short and slow growth defects. The ala6/7 phenotypes were rescued by the expression of either an ALA6-YFP or GFP-ALA6 fusion protein, which showed localization to both the plasma membrane and highly-mobile endomembrane structures. A mass spectrometry analysis of mature pollen grains revealed significant differences between ala6/7 and wild-type, both in the relative abundance of lipid classes and in the average number of double bonds present in acyl side chains. A change in the properties of the ala6/7 plasma membrane was also indicated by a ~10-fold reduction of labeling by lipophilic FM-dyes relative to wild-type. Together, these results indicate that ALA6 and ALA7 provide redundant activities that function to directly or indirectly change the distribution and abundance of lipids in pollen, and support a model in which ALA6 and ALA7 are critical for pollen fitness under normal and temperature-stress conditions. PMID:25954280

  7. The effect of a progesterone (P4) intravaginal device (CIDR) on resynchronisation of oestrus and embryonic loss in previously timed inseminated dairy heifers.

    PubMed

    Alnimer, M A

    2009-09-01

    A study was done to evaluate the effect of using progesterone (P4) intravaginal device (CIDR: controlled internal drug-releasing dispenser) to synchronise the return to oestrus of previously timed inseminated (TAI) dairy heifers, and to evaluate embryo survival and pregnancy rate (PR) in the return to oestrus heifers. At the onset of the artificial insemination (AI) breeding period (day -9), heifers were randomly assigned into two groups (treated group CGPG, n = 79) and (control group GPG, n = 83). Every heifer in both groups was injected with gonadotropin-releasing hormone (GnRH) agonist and prostaglandin F2-alpha (PGF2?) as follows: GnRH on day -9; PGF2? on day -2; GnRH and TAI on day 0. Heifers in both groups received TAI within 30 min after the second GnRH injection. Artificial insemination at first breeding was conducted for all heifers during 55 days from day 0. On day 14 after timed insemination, every heifer in the CGPG group received CIDR device for 6 days. Within 3 days after CIDR removal, more heifers in CGPG group showed oestrus within 1.9 days compared to heifers that showed oestrus within 2.9 days in the control. Within 10 days after CIDR removal, more heifers in the CGPG group showed oestrus within 2.4 days compared to heifers that showed oestrus within 6.7 days in the control. PRs on days 30 and 55 were not different between both groups, while PR on day 55 during September were higher (P = 0.032) in CGPG group (58.0%) than GPG group (37.0%). In addition, PR from first to second AI was higher (P = 0.037) for CGPG group (79.8%) than for GPG group (65.1%) but it was similar after that. Pregnancy losses between days 30 and 55 tended to be lower (P = 0.089) for the CGPG group (12.7%) compared to 25.1% for the GPG group. Interval between first and second AI was lower (P = 0.052) for the CGPG group (27.5 ± 1.6 days) compared to 31.6 ± 1.3 days for heifers in the GPG group but no differences were detected for intervals from second to third AI and from third to fourth AI between the two groups. Number of services per pregnancy was not different between CGPG and GPG groups. Results indicate that the CIDR device improved synchronisation to return to oestrus and increased PR to first AI during high temperature months by reducing embryonic losses. PMID:22444903

  8. u.s. department of commerce national institute of standards and technology manufacturing extension partnership W W W . n i s t . g o v / m e p 1 -8 0 0 -m e p -4 m F g

    E-print Network

    Perkins, Richard A.

    . With a comprehensive, custom Quality Management System in place, IMEC encouraged Corrugated Metals to pursue ISO 9001 extension partnership W W W . n i s t . g o v / m e p · 1 - 8 0 0 - m e p - 4 m F g For more information government contracts, Corrugated Metals decided to pursue quality, efficiency and safety improvements to make

  9. u.s. department of commerce national institute of standards and technology manufacturing extension partnership W W W . n i s t . g o v / m e p 1 -8 0 0 -m e p -4 m F g

    E-print Network

    Perkins, Richard A.

    innovation engineering process to learn a systematic way to create sustainable growth through innovation s t . g o v / m e p · 1 - 8 0 0 - m e p - 4 m F g 2013 innovation services lead to increased sales, new, facilitate more accurate billing and improve overall communication. After improving their sales and invoicing

  10. U.S. DEPARTMENT OF COMMERCE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY MANUFACTURING EXTENSION PARTNERSHIP W W W . N I S T . G O V / M E P 1 -8 0 0 -M E P -4 M F G

    E-print Network

    . Unlike traditional market research, TDMI directly considers the technical and market viability of your on its core product, Controlled Porosity Glass (CPG) for the DNA synthesis market. Continued research EXTENSION PARTNERSHIP W W W . N I S T . G O V / M E P · 1 - 8 0 0 - M E P - 4 M F G TECHNOLOGY-DRIVEN MARKET

  11. Safety analysis report: packages. Argonne National Laboratory SLSF test train shipping container, P-1 shipment. Fissile material. Final report

    Microsoft Academic Search

    1975-01-01

    The package is used to ship an instrumented test fuel bundle (test ; train) containing fissile material. The package assembly is Argonne National ; Laboratory (ANL) Model R1010-0032. The shipment is fissile class III. The ; packaging consists of an outer carbon steel container into which an inner ; container is placed; the inner container is separated from the outer

  12. Field Experiments

    Microsoft Academic Search

    Glenn W. Harrison; John A. List

    2004-01-01

    Experimental economists are leaving the reservation. They are recruiting subjects in the field rather than in the classroom, using field goods rather than induced valuations, and using field context rather than abstract terminology in instructions. We argue that there is something methodologically fundamental behind this trend. Field experiments differ from laboratory experiments in many ways. Although it is tempting to

  13. Herschel Experiment

    NSDL National Science Digital Library

    In this experiment, students replicate a version of the 1800 experiment in which a form of radiation other than visible light was discovered by the famous astronomer Sir Frederick William Herschel. Students use glass prisms, thermometers, and sunlight to detect the increase in temperature beyond the red end of the visible spectrum, thus detecting infrared light.

  14. TRIO experiment

    SciTech Connect

    Clemmer, R.G.; Finn, P.A.; Malecha, R.F.; Misra, B.; Billone, M.C.; Bowers, D.L.; Fischer, A.K.; Greenwood, L.R.; Mattas, R.F.; Tam, S.W.

    1984-09-01

    The TRIO experiment is a test of in-situ tritium recovery and heat transfer performance of a miniaturized solid breeder blanket assembly. The assembly (capsule) was monitored for temperature and neutron flux profiles during irradiation and a sweep gas flowed through the capsule to an anaytical train wherein the amounts of tritium in its various chemical forms were determined. The capsule was designed to operate at different temperatures and sweep gas conditions. At the end of the experiment the amount of tritium retained in the solid was at a concentration of less than 0.1 wppM. More than 99.9% of tritium generated during the experiment was successfully recovered. The results of the experiment showed that the tritium inventories at the beginning and at the end of the experiment follow a relationship which appears to be characteristic of intragranular diffusion.

  15. experiment, collaboration

    E-print Network

    -Departamento Energias Renovables, Plataforma Solar de Almeria, E-04080 Almeria, Spain Departamento de Lenguajes y; 5 Rainer Plaga The GRAAL experiment, ECRS Lodz July 2000 Location of GRAAL " Plataforma Solar de

  16. Poker Experiment

    NSDL National Science Digital Library

    Kyle Siegrist

    This resource consists of a Java applet and expository text. The applet simulates the basic poker experiment of dealing 5 cards from a standard deck. The random variable of interest is the type of hand.

  17. Control experiment

    NSDL National Science Digital Library

    Peggy Greb (USDA; ARS)

    2006-05-23

    There is a type of experiment in which a scientist uses a control variable approach. All conditions in the experiment will be the same except for one variable. When testing water tolerance of barley plants, for example, you could not water one plant, over-water one plant, under-water another plant, and water the last plant with the optimal amount of water and observe the results.

  18. Syntheses and characterizations of Cs2Cr3(BP4O14)(P4O13) and CsFe(BP3O11) compounds with novel borophosphate anionic partial structures.

    PubMed

    Zhang, Weilong; Cheng, Wendan; Zhang, Hao; Geng, Lei; Li, Yeyu; Lin, Chensheng; He, Zhangzhen

    2010-03-01

    Explorations of the A(I)-M(III)-B(III)-P(V)-O quinary system under solid-state reactions led to an anhydrous cesium-chromium borophosphate-phosphate and an anhydrous cesium-iron borophosphate, namely, Cs(2)Cr(3)(BP(4)O(14))(P(4)O(13)) (1) and CsFe(BP(3)O(11)) (2). They both feature complicated three-dimensional (3D) frameworks and represent the first examples of borophosphate frameworks with a P-O-P connection. Compound 1 contains a novel anionic borophosphate partial structure [B(P(2)O(7))(2)](5-) with B:P = 1:4 besides an isolated [P(4)O(13)](6-) anion. Its 3D structure is composed of a layer of [CrB(P(2)O(7))(2)](n)(2n-) and a neutral layer of [Cr(2)(P(4)O(13))](n) interconnected with the linking of P-O-Cr, and the Cs ions are located at the space. Compound 2 contains another novel borophosphate anionic unit of [B(PO(4))(P(2)O(7))](4-) with B:P = 1:3, which further bridges the Fe cations to constitute the whole structure. Both compounds are of high thermal stable and transparent in the range of 0.75-7.1 microm. Magnetic measurements indicate that there exist antiferromagnetic interactions in both compounds. PMID:20112999

  19. Experiment Databases

    NASA Astrophysics Data System (ADS)

    Vanschoren, Joaquin; Blockeel, Hendrik

    Next to running machine learning algorithms based on inductive queries, much can be learned by immediately querying the combined results of many prior studies. Indeed, all around the globe, thousands of machine learning experiments are being executed on a daily basis, generating a constant stream of empirical information on machine learning techniques. While the information contained in these experiments might have many uses beyond their original intent, results are typically described very concisely in papers and discarded afterwards. If we properly store and organize these results in central databases, they can be immediately reused for further analysis, thus boosting future research. In this chapter, we propose the use of experiment databases: databases designed to collect all the necessary details of these experiments, and to intelligently organize them in online repositories to enable fast and thorough analysis of a myriad of collected results. They constitute an additional, queriable source of empirical meta-data based on principled descriptions of algorithm executions, without reimplementing the algorithms in an inductive database. As such, they engender a very dynamic, collaborative approach to experimentation, in which experiments can be freely shared, linked together, and immediately reused by researchers all over the world. They can be set up for personal use, to share results within a lab or to create open, community-wide repositories. Here, we provide a high-level overview of their design, and use an existing experiment database to answer various interesting research questions about machine learning algorithms and to verify a number of recent studies.

  20. SANE experiment

    NASA Astrophysics Data System (ADS)

    Baghdasaryan, H.; SANE Collaboration

    2012-02-01

    The Spin Asymmetries of the Nucleon Experiment (SANE) is a measurement of parallel and near-perpendicular double spin asymmetries in an inclusive electron scattering. The main goal of the experiment was to measure A? and A80 and extract the spin asymmetries of the proton Ap1, Ap2 and spin structure functions gp1 and gp2. Using the Thomas Jefferson National Accelerator Facility's polarized electron beam and the University of Virginia's polarized frozen ammonia (14NH3) target in Hall C, the experiment ran in 2009, collecting data in a Q2 region from 2.5 to 6.5 GeV2 and between Bjorken x of 0.3 to 0.8. Particle detection was accomplished using the Big Electron Telescope Array (BETA), a novel non-magnetic detector. This talk will address the progress of the analysis designed to extract the proton spin asymmetries and structure functions. Preliminary results will be presented.

  1. Rutherford Experiment

    NSDL National Science Digital Library

    Wolfgang Christian

    The simulation below shows an interaction between two "particles." The interaction force is a 1/r2 force; that is, the interaction force varies as 1/r2 where r is the distance between them. However, it only "exists" when the particles are less than 0.2 m apart. This collision is similar to the type of collisions that occurred between alpha particles and gold nuclei in the famous Rutherford experiment. This experiment showed that the very massive nuclei is very small compared to the size of the atom.

  2. Digestion Experiments

    E-print Network

    Fraps, G. S. (George Stronach)

    1908-01-01

    , Pennsylvania Experi- ment Station.) The productive values of feeding stuffs and the nutrients which com- pose them have been measured in terms of fat by Kellner. The method of experiment consists in feeding the animal with a basal ration which is more than... approximately one-third was ash, sorrlcthing over one-third was protein, and less than one-third non- protein organic matter. .About 10 per cent of the total protein, 20 per cent of the total ash, and 3 per cent of the nitrogen-free ext solul~le in water...

  3. TRIO experiment

    Microsoft Academic Search

    R. G. Clemmer; P. A. Finn; R. F. Malecha; B. Misra; M. C. Billone; D. L. Bowers; A. K. Fischer; L. R. Greenwood; R. F. Mattas; S. W. Tam

    1984-01-01

    The TRIO experiment is a test of in-situ tritium recovery and heat transfer performance of a miniaturized solid breeder blanket assembly. The assembly (capsule) was monitored for temperature and neutron flux profiles during irradiation and a sweep gas flowed through the capsule to an anaytical train wherein the amounts of tritium in its various chemical forms were determined. The capsule

  4. Ballot Experiment

    NSDL National Science Digital Library

    Kyle Siegrist

    This resource consists of a Java applet and expository text. The applet is a simulation of the ballot experiment: The votes in an election are randomly counted. The event of interest is that the winning candidate is always ahead in the vote count.

  5. Triangle Experiment

    NSDL National Science Digital Library

    Kyle Siegrist

    This resource consists of a Java applet and expository text. The applet llustrates the triangle experiment: A stick is broken randomly into three parts. The events of interest are that the pieces form an acute triangle, an obtuse triangle, or no triangle.

  6. Birthday Experiment

    NSDL National Science Digital Library

    Kyle Siegrist

    This resource consists of a Java applet and expository text. The applet is a simulation of the birthday experiment: a sample of size n is chose at random and with replacement from the first m positive integers. The random variable of interest is the number of distinct sample values. The event of interest is that all sample values are distinct.

  7. Bertrand's Experiment

    NSDL National Science Digital Library

    Kyle Siegrist

    This resource consists of a Java applet and expository text. The applet is a simulation of Bertrand's experiment: a random chord on a cirle. The event of interest is whether the length of the chord is larger than the length of the inscribed equilateral triangle. Three models for generating the random chord can be used.

  8. Biodiesel Experiment

    NSDL National Science Digital Library

    Lawrence, Richard

    The Advanced Technology Environmental and Energy Center (ATEEC) provides this classroom activity on biodiesel. The experiment involves using some chemicals which may be considered extremely dangerous; educators should be sure to practice laboratory safety when using this lesson. Users must download this resource for viewing, which requires a free log-in. There is no cost to download the item.

  9. The structures of marialite (Me[subscript 6]) and meionite (Me[subscript 93]) in space groups P4[subscript 2]/n and I4/m, and the absence of phase transitions in the scapolite series

    SciTech Connect

    Antao, Sytle M.; Hassan, Ishmael (West Indies) [West Indies; (Calgary)

    2014-05-28

    The crystal structures of marialite (Me{sub 6}) from Badakhshan, Afghanistan and meionite (Me{sub 93}) from Mt. Vesuvius, Italy were obtained using synchrotron high-resolution powder X-ray diffraction (HRPXRD) data and Rietveld structure refinements. Their structures were refined in space groups I4/m and P42/n, and similar results were obtained. The Me{sub 6} sample has a formula Ca{sub 0.24}Na{sub 3.37}K{sub 0.24}[Al{sub 3.16}Si{sub 8.84}O{sub 24}]Cl{sub 0.84}(CO{sub 3}){sub 0.15}, and its unit-cell parameters are a = 12.047555(7), c = 7.563210(6) {angstrom}, and V = 1097.751(1) {angstrom}{sup 3}. The average (T1-O) distances are 1.599(1) {angstrom} in I4/m and 1.600(2) {angstrom} in P4{sub 2}/n, indicating that the T1 site contains only Si atoms. In P4{sub 2}/n, the average distances of (T2-O) = 1.655(2) and (T3-O) = 1.664(2) {angstrom} are distinct and are not equal to each other. However, the mean (T2,3-O) = 1.659(2) {angstrom} in P4{sub 2}/n and is identical to the (T2-O) = 1.659(1) {angstrom} in I4/m. The (M-O) [7] = 2.754(1) {angstrom} (M site is coordinated to seven framework O atoms) and M-A = 2.914(1) {angstrom}; these distances are identical in both space groups. The Me{sub 93} sample has a formula of Na{sub 0.29}Ca{sub 3.76}[Al{sub 5.54}Si{sub 6.46}O{sub 24}]Cl{sub 0.05}(SO{sub 4}){sub 0.02}(CO{sub 3}){sub 0.93}, and its unit-cell parameters are a = 12.19882(1), c = 7.576954(8) {angstrom}, and V = 1127.535(2) {angstrom}{sup 3}. A similar examination of the Me{sub 93} sample also shows that both space groups give similar results; however, the C-O distance is more reasonable in P4{sub 2}/n than in I4/m. Refining the scapolite structure near Me{sub 0} or Me{sub 100} in I4/m forces the T2 and T3 sites (both with multiplicity 8 in P4{sub 2}/n) to be equivalent and form the T2' site (with multiplicity 16 in I4/m), but (T2-O) is not equal to (T3-O) in P4{sub 2}/n. Using different space groups for different regions across the series implies phase transitions, which do not occur in the scapolite series.

  10. Insect adipokinetic hormone stimulates inositol phosphate metabolism: roles for both Ins(1,4,5)P3 and Ins(1,3,4,5)P4 in signal transduction?

    PubMed

    Van Marrewijk, W J; Van den Broek, A T; Gielbert, M L; Van der Horst, D J

    1996-09-18

    Adipokinetic hormones (AKHs) control the mobilization of energy reserves from the insect fat body as fuels for flight activity. As a part of our investigations on AKH signal transduction, we demonstrate in this study that the inositol lipid cycle may be involved in the action of AKH-I on fat body of the migratory locust. We show that [3H]inositol is incorporated into fat body phosphoinositides in vitro, whose hydrolysis leads to the formation of the following inositol phosphates (InsPs): Ins(1 and/or 3)P, Ins(4)P, Ins(1,3)P2, Ins(1,4)P2, Ins(3,4)P3, Ins(1,3,4)P3, Ins(1,4,5)P3 and Ins(1,3,4,5)P4. AKH stimulates the formation of these isomers, eliciting an increase in radioactivity of total InsPs already after 1 min. Mass measurements show that Ins(1,4,5)P3 levels are substantially enhanced by AKH, which is indicative of hormonal activation of phospholipase C. In cell-free tissue preparations, Ins(1,4,5)P3 is metabolized through dephosphorylation as well as further phosphorylation. Ins(1,3,4,5)P4 is dephosphorylated primarily to Ins(1,3,4)P3, although the ability for its reconversion to Ins(1,4,5)P3 suggests that in vivo Ins(1,3,4,5)P4 may function as a rapidly mobilizable pool for Ins(1,4,5)P3 generation. Metabolic pathways for the conversion of InsPs to inositol in the locust fat body are proposed. PMID:8902844

  11. Soil experiment

    NASA Technical Reports Server (NTRS)

    Hutcheson, Linton; Butler, Todd; Smith, Mike; Cline, Charles; Scruggs, Steve; Zakhia, Nadim

    1987-01-01

    An experimental procedure was devised to investigate the effects of the lunar environment on the physical properties of simulated lunar soil. The test equipment and materials used consisted of a vacuum chamber, direct shear tester, static penetrometer, and fine grained basalt as the simulant. The vacuum chamber provides a medium for applying the environmental conditions to the soil experiment with the exception of gravity. The shear strength parameters are determined by the direct shear test. Strength parameters and the resistance of soil penetration by static loading will be investigated by the use of a static cone penetrometer. In order to conduct a soil experiment without going to the moon, a suitable lunar simulant must be selected. This simulant must resemble lunar soil in both composition and particle size. The soil that most resembles actual lunar soil is basalt. The soil parameters, as determined by the testing apparatus, will be used as design criteria for lunar soil engagement equipment.

  12. Voter Experiment

    NSDL National Science Digital Library

    Kyle Siegrist

    This resource consists of a Java applet and expository text. The applet is a simulation of the voter experiment, an interacting partile system that consists of a rectangular array of sites. At each discrete time unit, a site is chosen at random, a neighboring site is chosen, and the color of the first site is changed to that of the neighbor. The applet illustrates clustering of the colors and convergence to consensus.

  13. Matching Experiment

    NSDL National Science Digital Library

    Kyle Siegrist

    This resource consists of a Java applet and expository text. The applet is a simulation of the matching experiment, which consists of a random permutation of the first n positive integers. The random variable of interest is the number of matches (the number of integers in the random permutation that are in their correct positions). The applet illustrates the distribution of the number of matches and the convergence to the Poisson distribution.

  14. Ab initio calculations of the {33}S 3p4 3P_J and {33}S- / {37,35}Cl 3p5 2Po_J hyperfine structures

    E-print Network

    Carette, T

    2011-01-01

    We present highly correlated multi-configuration Hartree-Fock (MCHF) calculations of the hyperfine structure of the 3p5 2Po_J levels of {33}S- and {35,37}Cl. We obtain a good agreement with observation. The hyperfine structure of the neutral sulfur {33}S 3p4 3P_J lowest multiplet that has never been measured to the knowledge of the authors, is also estimated theoretically. We discuss some interesting observations made on the description of the atomic core in MCHF theory.

  15. Accurate Lifetimes and Absolute Transition Rates for Ultraviolet Transitions from 3D5(4G) 4P and 3D5(4P) 4P levels in MN II

    NASA Astrophysics Data System (ADS)

    Kling, Rainer; Schnabel, Roman; Griesmann, Ulf

    2001-05-01

    A recently developed, laser-induced fluorescence technique was used to measure the lifetimes of 14 3d5(4G)4p and 3d5(4P)4p levels in the Mn+ ion. Branching fractions for electric dipole transitions from these levels were measured with a vacuum ultraviolet Fourier transform spectrometer, using a hollow-cathode lamp and a Penning discharge source. Based on these new measurements, absolute electric dipole transition rates for about 170 spectral lines in the ultraviolet and vacuum ultraviolet were determined. The uncertainty of the transition rates is less than 5% for the strong transitions.

  16. System parameters, transit times and secondary eclipse constraints of the exoplanet systems HAT-P-4, TrES-2, TrES-3 and WASP-3 from the NASA EPOXI Mission of Opportunity

    E-print Network

    Christiansen, Jessie L; Charbonneau, David; Deming, Drake; Holman, Matthew J; Madhusudhan, Nikku; Seager, Sara; Wellnitz, Dennis D; Barry, Richard K; Livengood, Timothy A; Hewagama, Tilak; Hampton, Don L; Lisse, Carey M; A'Hearn, Michael F

    2010-01-01

    As part of the NASA EPOXI Mission of Opportunity, we observed seven known transiting extrasolar planet systems in order to construct time series photometry of extremely high phase coverage and precision. Here we present the results for four "hot-Jupiter systems" with near-solar stars - HAT-P-4, TrES-3, TrES-2 and WASP-3. We observe ten transits of HAT-P-4, estimating the planet radius Rp = 1.332 \\pm 0.052 RJup, the stellar radius R \\star = 1.602 \\pm 0.061 R \\odot, the inclination i = 89.67 \\pm 0.30 degrees and the transit duration from first to fourth contact T = 255.6 \\pm 1.9 minutes. For TrES-3, we observe seven transits, and find Rp = 1.320 \\pm 0.057 RJup, R\\star = 0.817 \\pm 0.022 R\\odot, i = 81.99 \\pm 0.30 degrees and T = 81.9 \\pm 1.1 minutes. We also note a long term variability in the TrES-3 light curve, which may be due to star spots. We observe nine transits of TrES-2, and find Rp = 1.169 \\pm 0.034 RJup, R\\star = 0.940 \\pm 0.026 R\\odot, i = 84.15 \\pm 0.16 degrees and T = 107.3 \\pm 1.1 minutes. Finally...

  17. Crystal structure, spectroscopic, magnetic and electronic structure studies of a novel Cu(II) amino acid complex [Cu(L-arg)2(H2O)]2(P4O12)·8H2O

    NASA Astrophysics Data System (ADS)

    Hemissi, H.; Nasri, M.; Abid, S.; Al-Deyab, S. S.; Dhahri, E.; Hlil, E. K.; Rzaigui, M.

    2012-12-01

    Single crystals of a novel copper (II) complex with the amino acid L-arginine (L-arg) and cyclotetraphosphate, [Cu(L-arg)2(H2O)]2(P4O12)·8H2O, were prepared in aqueous solution and were characterized by X-ray diffraction, spectroscopy (diffuse reflectance, UV-vis and IR) and thermal analysis. Magnetic measurements and electronic structure calculations were also performed. Crystal structure determination reveals that this compound has a nonsymmetrical atomic arrangement, containing mainly a binuclear [Cu(L-arg)2(H2O)]24+ cation and an uncoordinated cyclotetraphosphate counter-anion (P4O124-). The tetravalent cation contains two independent Cu(II) ions in two different chemical environments. This compound exhibits an antiferromagnetic (AFM) to paramagnetic (PM) phase transition at a temperature (TN) lower than 2 K. The values of paramagnetic Curie-Weiss temperature (?cw) and the exchange parameter (J/KB) emphasize the existence of an antiferromagnetic interaction between the neighboring copper ions.

  18. SYSTEM PARAMETERS, TRANSIT TIMES, AND SECONDARY ECLIPSE CONSTRAINTS OF THE EXOPLANET SYSTEMS HAT-P-4, TrES-2, TrES-3, and WASP-3 FROM THE NASA EPOXI MISSION OF OPPORTUNITY

    SciTech Connect

    Christiansen, Jessie L.; Ballard, Sarah; Charbonneau, David; Holman, Matthew J. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Deming, Drake; Barry, Richard K.; Livengood, Timothy A.; Hewagama, Tilak [Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Madhusudhan, Nikku; Seager, Sara [Massachusetts Institute of Technology, Cambridge, MA 02159 (United States); Wellnitz, Dennis D.; A'Hearn, Michael F. [University of Maryland, College Park, MD 20742 (United States); Hampton, Don L. [University of Alaska Fairbanks, Fairbanks, AK 99775 (United States); Lisse, Carey M., E-mail: jchristi@cfa.harvard.edu [Johns Hopkins University Applied Physics Laboratory, Laurel, MD 20723 (United States)

    2011-01-10

    As part of the NASA EPOXI Mission of Opportunity, we observed seven known transiting extrasolar planet systems in order to construct time series photometry of extremely high phase coverage and precision. Here we present the results for four 'hot-Jupiter systems' with near-solar stars-HAT-P-4, TrES-3, TrES-2, and WASP-3. We observe 10 transits of HAT-P-4, estimating the planet radius R{sub p} = 1.332 {+-} 0.052 R{sub Jup}, the stellar radius R{sub *} = 1.602 {+-} 0.061 R{sub sun}, the inclination i = 89.67 {+-} 0.30 deg, and the transit duration from first to fourth contact {tau} = 255.6 {+-} 1.9 minutes. For TrES-3, we observe seven transits and find R{sub p} = 1.320 {+-} 0.057 R{sub Jup}, R{sub *} = 0.817 {+-} 0.022 R{sub sun}, i = 81.99 {+-} 0.30 deg, and {tau} = 81.9 {+-} 1.1 minutes. We also note a long-term variability in the TrES-3 light curve, which may be due to star spots. We observe nine transits of TrES-2 and find R{sub p} = 1.169 {+-} 0.034 R{sub Jup}, R{sub *} = 0.940 {+-} 0.026 R{sub sun}, i = 84.15 {+-} 0.16 deg, and {tau} = 107.3 {+-} 1.1 minutes. Finally, we observe eight transits of WASP-3, finding R{sub p} = 1.385 {+-} 0.060 R{sub Jup}, R{sub *} = 1.354 {+-} 0.056 R{sub sun}, i = 84.22 {+-} 0.81 deg, and {tau} = 167.3 {+-} 1.3 minutes. We present refined orbital periods and times of transit for each target. We state 95% confidence upper limits on the secondary eclipse depths in our broadband visible bandpass centered on 650 nm. These limits are 0.073% for HAT-P-4, 0.062% for TrES-3, 0.16% for TrES-2, and 0.11% for WASP-3. We combine the TrES-3 secondary eclipse information with the existing published data and confirm that the atmosphere likely does not have a temperature inversion.

  19. Electrophoresis experiment, experiment MA-014

    NASA Technical Reports Server (NTRS)

    Hannig, K.; Wirth, H.

    1976-01-01

    A continuous, free flow electrophoresis study was conducted during the Apollo Soyuz Test Project mission to investigate and evaluate the increase in sample flow rate and sample resolution achievable in space. The electrophoresis equipment was designed for the separation of four mixtures of biological cells with variable sample flow rates, buffer flow rates, and electric field gradients. Separation quality was assessed by measuring the light from a quartz lamp through the electrophoresis channel and on to a photodiode system. The preliminary results indicate that all monitored systems operated correctly during the experiment. The optical system produced a light that was too bright to discern true cell distributions, but data were received that show a distribution of separated cells.

  20. Electrophoresis experiment. Experiment MA-014

    NASA Technical Reports Server (NTRS)

    Hannig, K. H.

    1977-01-01

    A continuous free-flow electrophoresis study was conducted during the Apollo-Soyuz Test Project Mission to investigate and evaluate the increase in sample flow rate and sample resolution achievable in space. The electrophoresis equipment was designed for the separation of four mixtures of biological cells with variable sample flow rates, buffer flow rates, and electric field gradients. Separation quality was assessed by measuring the light from a quartz lamp through the electrophoresis channel and onto a photodiode system. The data evaluation indicates that all monitored systems operated correctly during the experiment. The optical system produced a light that was too bright to discern true cell distributions, but final analysis of scientific data by computer processing shows the expected distribution of separated cells.

  1. Reanalysis of the astrophysical S(E) factors of the 6Li(d,?)4He, 7Li(p,?)4He and 6Li(p,?)3He reactions

    NASA Astrophysics Data System (ADS)

    Wang, T. S.; Guan, X. C.; Fang, K. H.; Zhao, J. T.; He, Q. H.; Lan, M. C.; Xu, X. X.

    2012-01-01

    The experimental data of the 6Li(d,?)4He,7Li(p,?)4He and 6Li(p,?)3He reactions obtained by other groups are reanalyzed in this work to extract their respective astrophysical S(E) factors and the screening energies provided by different environments (LiF solid targets and molecular H2 or D2 gas targets). Different from previous authors who investigated these three reactions independently, we study them simultaneously, based on the hypothesis that the screening effects are independent of the isotopic effects and the fact that the screening effects depend on the environments. The present extracted astrophysical S(E) factors result in Sbare(0) = 20.5 ± 0.5, 0.0616 ± 0.0017 and 3.63 ± 0.13 MeV b for the 6Li(d,?)4He, 7Li(p,?)4He and 6Li(p,?)3He reactions, respectively. The screening energies are 310 ± 109 and 218 ± 38 eV for the LiF solid targets and molecular H2 or D2 gas targets, respectively. These deduced screening energies are smaller than that observed by Engstler et al, and the value of Us = 218 ± 38 eV for the molecular H2 or D2 gas targets coincides with the value of 186 eV estimated from the adiabatic limit, while the value of Us = 310 ± 109 eV for the LiF solid targets is still slightly larger than that estimated from theoretical predictions.

  2. Microgravity Scaling Theory Experiment - Experiment Implementation Plan

    NASA Technical Reports Server (NTRS)

    Hahn, I.; Weilert, M.

    1999-01-01

    Microgravity Scaling Theory Experiment (MISTE) is a candidate experiment competitively peer reviewed and selected for flight definition from the 1996 Fundamental Physics NASA Research Announcement (NRA).

  3. Near-death experience as mystical experience

    Microsoft Academic Search

    John Pennachio

    1986-01-01

    Near-death experience exhibits many attributes of mystical awareness. Assessing the mystical quality of psychedelic experience, Walter Pahnke identified a nine-category typology of mystical experience. It is used here to illustrate the mystical nature of near-death experience. The typology also describes the self-transformation which follows the mystical state of consciousness. Self-transformation results from near-death experience. Pahnke's mystical typology characterizes the near-death

  4. Distinct Transmissibility Features of TSE Sources Derived from Ruminant Prion Diseases by the Oral Route in a Transgenic Mouse Model (TgOvPrP4) Overexpressing the Ovine Prion Protein

    PubMed Central

    Arsac, Jean-Noël; Baron, Thierry

    2014-01-01

    Transmissible spongiform encephalopathies (TSEs) are a group of fatal neurodegenerative diseases associated with a misfolded form of host-encoded prion protein (PrP). Some of them, such as classical bovine spongiform encephalopathy in cattle (BSE), transmissible mink encephalopathy (TME), kuru and variant Creutzfeldt–Jakob disease in humans, are acquired by the oral route exposure to infected tissues. We investigated the possible transmission by the oral route of a panel of strains derived from ruminant prion diseases in a transgenic mouse model (TgOvPrP4) overexpressing the ovine prion protein (A136R154Q171) under the control of the neuron-specific enolase promoter. Sources derived from Nor98, CH1641 or 87V scrapie sources, as well as sources derived from L-type BSE or cattle-passaged TME, failed to transmit by the oral route, whereas those derived from classical BSE and classical scrapie were successfully transmitted. Apart from a possible effect of passage history of the TSE agent in the inocula, this implied the occurrence of subtle molecular changes in the protease-resistant prion protein (PrPres) following oral transmission that can raises concerns about our ability to correctly identify sheep that might be orally infected by the BSE agent in the field. Our results provide proof of principle that transgenic mouse models can be used to examine the transmissibility of TSE agents by the oral route, providing novel insights regarding the pathogenesis of prion diseases. PMID:24797075

  5. Diabetes Experience Spring 2014 Interprofessional Diabetes Experience

    E-print Network

    Thomas, David D.

    Diabetes Experience Spring 2014 Interprofessional Diabetes Experience Phar 6226/Nurs 5011 Spring the opportunity to learn in-depth knowledge of diabetes mellitus through active, hands-on learning experience of living with diabetes, in which they will give "insulin" injections and check blood glucoses

  6. Does the Frequency of Pay-for-Performance Payment Matter?—Experience from a Randomized Trial

    PubMed Central

    Chung, Sukyung; Palaniappan, Latha; Wong, Eric; Rubin, Haya; Luft, Harold

    2010-01-01

    Objective To examine the effects of incentive payment frequency on quality measures in a physician-specific pay-for-performance (P4P) experiment. Study Setting A multispecialty physician group practice. Study Design In 2007, all primary care physicians (n=179) were randomized into two study arms differing by the frequency of incentive payment, either four quarterly bonus checks or a single year-end bonus (maximum of U.S.$5,000/year for both arms). Data Collection/Extraction Methods Data were extracted from electronic health records. Quality measure scores between the two arms over four quarters were compared. Principal Findings There was no difference between the two arms in average quality measure score or in total bonus amount earned. Conclusions Physicians' responses to a P4P program with a small maximum bonus do not differ by frequency of bonus payment. PMID:20059568

  7. Notes on Experiments.

    ERIC Educational Resources Information Center

    Physics Education, 1989

    1989-01-01

    Described are three physics experiments: (1) "Holographic Prism"; (2) "Teaching about Energy with the Gravicar"; and (3) "The Coherer." In each experiment, a brief description of the experiment devised is provided with diagrams and references. (YP)

  8. Evolution of fcc Cu clusters and their structure changes in the soft magnetic Fe85.2Si1B9P4Cu0.8 (NANOMET) and FINEMET alloys observed by X-ray absorption fine structure

    NASA Astrophysics Data System (ADS)

    Matsuura, M.; Nishijima, M.; Takenaka, K.; Takeuchi, A.; Ofuchi, H.; Makino, A.

    2015-05-01

    It is known that Cu plays an essential role in reducing the grain size of precipitated bcc Fe(Si) nanocrystallites in a nanocrystalline soft-magnetic Fe85.2Si1B9P4Cu0.8 (NANOMET®) alloys like as an Fe73.5Si13.5B9Nb3Cu1 (FINEMET®). However, significant differences are there between two alloys; NANOMET has much higher iron content (˜85%) than FINEMET (73.5%) and the former contains P instead of Nb for the latter. In the present work, the local structure around Cu in FINEMET was measured by X-ray absorption fine structure (XAFS) at 20 K and compared with those of NANOMET during nanocrystallization. Definite differences between NANOMET and FINEMET are found in the way of the evolution of Cu clusters during nanocrystallization. In FINEMET, an fcc structure of Cu is recognized in an as-quenched ribbon indicating existence of a small number of Cu clusters or a very small size of Cu clusters which is stable up to 450 °C, while the fcc Cu clusters are developed rapidly above 450 °C. An fcc structure of the Cu clusters in FINEMET is retained all the way to the end of the nanocrystallization. On the contrary, for NANOMET the local structure around Cu changes in a sequence as "amorphous ? fcc ? bcc ? fcc" by annealing. The reasons of such different behaviors of the local structure around Cu during nanocrystallization are discussed in terms of different contributions of Cu clusters in bcc Fe precipitation between FINEMET and NANOMET. A significantly fast crystallization process with an extraordinary large heat release can be another reason for the transition of the local structure around Cu from fcc to bcc for NANOMET.

  9. Presence of diadenosine 5',5''' -P1, P4-tetraphosphate (Ap4A) in mamalian cells in levels varying widely with proliferative activity of the tissue: a possible positive "pleiotypic activator".

    PubMed Central

    Rapaport, E; Zamecnik, P C

    1976-01-01

    An accurate assay of diadenosine 5',5'''- P1,P4-tetraphosphate [A(5') pppp(5')A], which was shown to be formed in vitro in the backreaction of the amino acid activation step, has been developed in various cell lines in culture and in normal mouse liver or hepatoma in vivo. Use of radioactive labeling of acid-soluble nucleotides to high specific activity followed by chromatographic separation techniques yielded levels of Ap4A varying from 5 to 0.05 muM (from 30 pmol/mg of protein to 0.15 pmol), depending on the doubling time of the cell line or the proliferative state of the cells. The levels of Ap4A incells is inversely related to their doubling time, varying from 0.1 X 10(-4) of the cellular ATP levels in slowly growing cells to 20 X 10(-4) of the ATP levels of cells with rapid doubling times. The steady-state levels of ATP of different cell lines, although showing some fluctuations, are not related to the doubling time of the cells. Arrest of cellular proliferation by serum deprivation or amino acid starvation, which does not alter the cellular ATP levels more than 2-fold, does nevertheless cause a decrease of 30 to 50-fold in the Ap4A levels. Inhibition of protein synthesis by pactamycin or puromycin, or inhibition of DNA synthesis by hydroxyurea, leads to a more dramatic decrease of 50 to 100-fold in intracellular Ap4A levels. The metabolic lability of Ap4A is also demonstrated by its rapid depletion after decreases in the ATP/ADP ratio. The possibility of Ap4A being a metabolic "signal nucleotide" that is formed at the onset of protein synthesis and is active in positive growth regulation (positive pleiotypic activation) is discussed. PMID:1069282

  10. The use of anatomically drop-shaped bioactive glass S53P4 implants in the reconstruction of orbital floor fractures-A prospective long-term follow-up study.

    PubMed

    Stoor, P; Mesimäki, Karri; Lindqvist, Christian; Kontio, Risto

    2015-07-01

    An isolated fracture of the orbital floor needs reconstruction if there is a clear herniation of adipose tissue or of the rectus inferior muscle into the maxillary sinus. A prospective study was carried out treating 20 patients with an isolated blow-out fracture of the orbital floor or with a combined zygomatico-orbito-maxillary complex fracture, using a newly designed anatomically drop-shaped implants made of bioactive glass (BAG) S53P4. Computed tomography (CT) was performed immediately postoperatively to confirm the correct position of the plate. The patients were followed up for an average of 32 months clinically and radiologically with magnetic resonance imaging (MRI) for an average of 31 months. None of the patients had any signs of complications related to the implant and the clinical outcome was very good. None of the patients had persisting diplopia. The level of the pupillas was normal in 15 of 20 patients. Minor hypo-ophthalmos ranging from 0.5 to 1.0 mm was observed in three patients, and moderate hypo-ophthalmos of 2.0 mm was seen in one patient. Hyperophthalmos of 1.0 mm was seen in one patient. Minor enophthalmos on the operated side ranging from 0.5 to 1.0 mm was seen in eight patients. Mild to moderate paraesthesia of the infraorbital nerve was observed in six patients. The immediate postoperative CT and the long term follow-up MRI revealed that the drop-shaped BAG implants retained their correct position in the orbital floor and did not show any evidence of losing their original shape or material resorption. No adverse tissue reaction was associated with the material. Due to the anatomical drop shape, the implants could successfully maintain the orbital volume and compensate for the retrobulbar adipose tissue atrophy. PMID:25957104

  11. Identification of gene structure and subcellular localization of human centaurin a2, and p42 IP4 , a family of two highly homologous, Ins 1,3,4,5-P 4 -\\/PtdIns 3,4,5-P 3 -binding, adapter proteins

    Microsoft Academic Search

    Theodor Hanck; Rolf Stricker; Fariba Sedehizade; Georg Reiser

    2004-01-01

    Proteins which recognize the two messengers phosphatidy- linositol 3,4,5-trisphosphate (PtdInsP3), a membrane lipid, and inositol 1,3,4,5-tetrakisphosphate (InsP4), a water-soluble lig- and, play important roles by integrating external stimuli, which lead to differentiation, cell death or survival. p42 IP4 , a PtdInsP3\\/ InsP4-binding protein, is predominantly expressed in brain. The recently described centaurin a2 of similar molecular mass which is 58%

  12. Double beta decay experiments

    E-print Network

    A. S. Barabash

    2006-02-22

    The present status of double beta decay experiments are reviewed. The results of the most sensitive experiments, NEMO-3 and CUORICINO, are discussed. Proposals for future double beta decay experiments are considered. In these experiments sensitivity for the effective neutrino mass will be on the level of (0.1-0.01) eV.

  13. EXPERIMENTS JUNE 15, 1965

    E-print Network

    Rathbun, Julie A.

    NPC 500-9 I APOLLO EXPERIMENTS GUIDE JUNE 15, 1965 NATIONAL AERONAUTICS AND SPACE ADMINISTRATION. I-1 of the "Apollo Experiments Guide;' June 15, 1965, NPC 500-9. #12;3. PROCEDURES 3.l EXPERIMENT FLOI-7 PATH Figure 3-l depicts a typical flow path which experiments follow from submission to launch. Signi- ficant

  14. Experiments in Electrochemistry

    NSDL National Science Digital Library

    Carboni, Giorgio.

    1998-01-01

    Provided by the Fun Science Gallery, Experiments in Electrochemistry offers both teachers and students documentation for seven simple experiments to investigate conductors, batteries, potentials, and galvanic deposition. Each experiment is accompanied by a list of materials, explanatory text, and at least one figure that facilitates a scientific understanding of the experiment.

  15. Lithium battery space experiment

    SciTech Connect

    Chmlelewski, A.B.; Surampudi, S.; Bennett, R.; Frank, H.; Mueller, R. [Jet Propulsion Lab., Pasadena, CA (United States)

    1995-12-31

    The In-Space Technology Experiments Program selected the Jet Propulsion Laboratory to conduct a Phase A study of the Lithium Battery Experiment. The experiment will mark the first time a rechargeable lithium battery will be flown in space. The operation of the battery involves lithium deposition and dissolution processes. Micro gravity influences these processes significantly. The experiment will check the rate capability, discharge voltage, capacity and the phenomena affecting cycle life. The paper describes the design and methodology of this experiment.

  16. Biomedical experiments. Part A: Biostack experiment

    NASA Technical Reports Server (NTRS)

    Buecker, H.; Horneck, G.; Reinholz, E.; Scheuermann, W.; Ruether, W.; Graul, E. H.; Planel, H.; Soleilhavoup, J. P.; Cuer, P.; Kaiser, R.

    1972-01-01

    The biostack experiment is described which was designed to study the biologic effects of individual heavy nuclei of galactic cosmic radiation during space flight outside the magnetosphere of the earth. Specifically, the biostack experiment was designed to promote research on the effects of high energy/high Z particles of galactic cosmic radiation on a broad spectrum of biologic systems, from the molecular to the highly organized and developed forms of life. The experiment was considered unique and scientifically meritorious because of its potential yield of information - currently unavailable on earth - on the interaction of biologic systems with the heavy particles of galactic cosmic radiation.

  17. Technique of analysis and error detection for thermo-hydraulic system data

    SciTech Connect

    Bordner, G.L.

    1985-01-01

    Statistical techniques based on estimation theory were developed for the analysis of steady-state data from thermo-hydraulic systems, which could be either experimental loops or operating power plants. The method seeks to resolve errors in the component heat balances which describe the system, to obtain system parameter estimates which are more accurate than the raw data, and to flag possible faulty sensors. Sample results are given for the analysis of test data from the Sodium Loop Safety Faciltiy (SLSF) P3 experiment.

  18. Mental Rotation Experiment

    NSDL National Science Digital Library

    This is the entry page for the Mental Rotation Experiment. This experiment presents 16 different pairs of three dimensional objects. Users judge whether the objects are the same or different. Responses are timed.

  19. First Impressions Experiment

    NSDL National Science Digital Library

    This is the entry page for participation in the first impressions experiment. This study allows participants to experience the formation of initial impressions and the roles minority/majority status and positive/negative attributes play in that formation process.

  20. Motional EMF demonstration experiment

    NASA Astrophysics Data System (ADS)

    Kingman, Robert; Popescu, Sabin

    2001-03-01

    A simple quantitative motional emf experiment. The induced voltage is recorded in this computer-based experiment as a coil is moved through the field of a permanent magnet. Results compare closely with predicted values.

  1. Portable controls experiments

    E-print Network

    Larson, Richard Winston

    2012-01-01

    Experiments for controls classes like MIT's 2.004 require large lab setups and expensive equipment such as oscilloscopes and function generators. We developed a series of controls experiments based on National Instruments' ...

  2. Notes on Experiments.

    ERIC Educational Resources Information Center

    Physics Education, 1984

    1984-01-01

    Describes apparatus needed and instructions for conducting four experiments. Experiments focus on light waves, measurement of contact resistance, demonstration of longitudinal waves, and a simple method of measuring the refractive indices of transparent plates and liquids. (JM)

  3. Experience and content

    E-print Network

    Byrne, Alex

    The ‘content view’, in slogan form, is ‘Perceptual experiences have representational content’. I explain why the content view should be reformulated to remove any reference to ‘experiences’. I then argue, against Bill ...

  4. Experience and Content

    E-print Network

    Byrne, Alex

    The 'content view', in slogan form, is 'Perceptual experiences have representational content'. I explain why the content view should be reformulated to remove any reference to 'experiences'. I then argue, against Bill ...

  5. Buffon's Coin Experiment

    NSDL National Science Digital Library

    Kyle Siegrist

    This resource consists of a Java applet and expository text. The applet simulates Buffon's coin experiment. The radius of the coin can be varied. The applet illustrates a random experiment, the sample space, random variables, events, probability, and relative frequency.

  6. Experiments and Calculations.

    ERIC Educational Resources Information Center

    Siddons, J. C.

    1982-01-01

    Discusses several science experiments/activities and their associated measurements. These include a simple projectile activity, cartesian diver (used to measure altitude and atmospheric pressure), experiment demonstrating atmospheric pressure, and activities using a stroboscope, and electrometer. (JN)

  7. STEP Experiment Requirements

    NASA Technical Reports Server (NTRS)

    Brumfield, M. L. (compiler)

    1984-01-01

    A plan to develop a space technology experiments platform (STEP) was examined. NASA Langley Research Center held a STEP Experiment Requirements Workshop on June 29 and 30 and July 1, 1983, at which experiment proposers were invited to present more detailed information on their experiment concept and requirements. A feasibility and preliminary definition study was conducted and the preliminary definition of STEP capabilities and experiment concepts and expected requirements for support services are presented. The preliminary definition of STEP capabilities based on detailed review of potential experiment requirements is investigated. Topics discussed include: Shuttle on-orbit dynamics; effects of the space environment on damping materials; erectable beam experiment; technology for development of very large solar array deployers; thermal energy management process experiment; photovoltaic concentrater pointing dynamics and plasma interactions; vibration isolation technology; flight tests of a synthetic aperture radar antenna with use of STEP.

  8. Experiments in Magnetohydrodynamics

    ERIC Educational Resources Information Center

    Rayner, J. P.

    1970-01-01

    Describes three student experiments in magnetohydrodynamics (MHD). In these experiments, it was found that the electrical conductivity of the local water supply was sufficient to demonstrate effectively some of the features of MHD flowmeters, generators, and pumps. (LC)

  9. NASTRAN: Users' experiences

    NASA Technical Reports Server (NTRS)

    1973-01-01

    The proceedings of a conference on NASA Structural Analysis (NASTRAN) to analyze the experiences of users of the program are presented. The subjects discussed include the following: (1) statics and buckling, (2) vibrations and dynamics, (3) substructing, (4) new capability, (5) user's experience, and (6) system experience. Specific applications of NASTRAN to spacecraft, aircraft, nuclear power plants, and materials tests are reported.

  10. Double beta decay experiments

    E-print Network

    A. S. Barabash

    2011-07-28

    The present status of double beta decay experiments is reviewed. The results of the most sensitive experiments are discussed. Proposals for future double beta decay experiments with a sensitivity to the $$ at the level of (0.01--0.1) eV are considered.

  11. Radiochemical solar neutrino experiments

    Microsoft Academic Search

    V. N. Gavrin; B. T. Cleveland

    2007-01-01

    Radiochemical experiments have been crucial to solar neutrino research. Even today, they provide the only direct measurement of the rate of the proton-proton fusion reaction, p + p --> d + e^+ + nu_e, which generates most of the Sun's energy. We first give a little history of radiochemical solar neutrino experiments with emphasis on the gallium experiment SAGE --

  12. Viscosity Of Liquids - Experiment

    NSDL National Science Digital Library

    Classroom experiment to illustrate the viscosity of different liquids by measuring how quickly pebbles sink through them. The site describes all of the required material for the experiment and also gives a detailed chart for recording the results of the experiment. Altogether, the site is a great activity for the classroom.

  13. Using Experience for Learning.

    ERIC Educational Resources Information Center

    Boud, David, Ed.; And Others

    This book contains 13 articles on learning from experience and its relationship to adult learning and adult education. The introductory article, "Understanding Learning from Experience" (Boud, Cohen, Walker), examines five propositions about learning from experience. The following papers are organized into three sections that focus respectively on…

  14. Introduction Photoproduction Experiments

    E-print Network

    Credé, Volker

    Introduction Photoproduction Experiments The FROST Program at JLab Summary Search for N Resonances, Japan 10/06/2006 V. Credé Search for N Resonances in Double-Polarization Experiments #12;Introduction Photoproduction Experiments The FROST Program at JLab Summary Outline 1 Introduction Baryon Spectroscopy 2

  15. Rethinking Work Experience.

    ERIC Educational Resources Information Center

    Miller, Andrew; And Others

    This book on work experience programs in the United Kingdom begins with "History and Policy Context" (Ian Jamieson, Andrew Miller), which reviews the development of work experience in the United Kingdom, considers the current policy framework, and poses possible future scenarios. "The Concept of Work Experience" (A. G. Watts) explores the concept…

  16. Basic Experiments in Telecommunications.

    ERIC Educational Resources Information Center

    Andresen, S. G.

    Presented is a set of laboratory experiments developed to provide students with demonstrations and hands-on experiences with a variety of basic communications methods. These experiments may be used with students who have training in engineering, as well as those with social sciences who have no engineering background. Detailed exercises dealing…

  17. Results from hadroproduction experiments

    E-print Network

    Boris A. Popov

    2011-06-22

    The hadroproduction experiments HARP, MIPP and NA61 (SHINE) as well as their implications for neutrino physics are discussed. HARP measurements have already been used for precise predictions of neutrino beams in K2K and MiniBooNE/SciBooNE experiments and are also being used to improve the atmospheric neutrino flux predictions and to help in the optimization of neutrino factory and super-beam designs. The MIPP experiment has nearly finalized measurements of hadron production from the NuMI target used in the MINOS experiment. First measurements released recently by the NA61 (SHINE) experiment are of significant importance for a precise prediction of the J-PARC neutrino beam used for the first stage of the T2K experiment. All three experiments - HARP, MIPP and NA61 - provide also a large amount of input for validation and tuning of hadron production models in Monte-Carlo generators.

  18. The Experience of Emotion

    PubMed Central

    Barrett, Lisa Feldman; Mesquita, Batja; Ochsner, Kevin N.; Gross, James J.

    2007-01-01

    Experiences of emotion are content-rich events that emerge at the level of psychological description, but must be causally constituted by neurobiological processes. This chapter outlines an emerging scientific agenda for understanding what these experiences feel like and how they arise. We review the available answers to what is felt (i.e., the content that makes up an experience of emotion) and how neurobiological processes instantiate these properties of experience. These answers are then integrated into a broad framework that describes, in psychological terms, how the experience of emotion emerges from more basic processes. We then discuss the role of such experiences in the economy of the mind and behavior. PMID:17002554

  19. Double Beta Decay Experiments

    SciTech Connect

    Nanal, Vandana [Dept. of Nuclear and Atomic Physics, Tata Institute of Fundamental Research, Mumbai 400 005 (India)

    2011-11-23

    At present, neutrinoless double beta decay is perhaps the only experiment that can tell us whether the neutrino is a Dirac or a Majorana particle. Given the significance of the 0{nu}{beta}{beta}, there is a widespread interest for these rare event studies employing a variety of novel techniques. This paper describes the current status of DBD experiments. The Indian effort for an underground NDBD experiment at the upcoming INO laboratory is also presented.

  20. Radiochemical solar neutrino experiments

    Microsoft Academic Search

    V. N. Gavrin; B. T. Cleveland

    2007-01-01

    Radiochemical experiments have been crucial to solar neutrino research. Even\\u000atoday, they provide the only direct measurement of the rate of the\\u000aproton-proton fusion reaction, p + p --> d + e^+ + nu_e, which generates most\\u000aof the Sun's energy. We first give a little history of radiochemical solar\\u000aneutrino experiments with emphasis on the gallium experiment SAGE --

  1. Gravitational Radiation Experiments

    Microsoft Academic Search

    J. Weber

    1970-01-01

    A summary is given of the statistics and coincidences of the Argonne-Maryland gravitational-radiation-detector array. New experiments have been carried out. These include a parallel coincidence experiment in which one coincidence detector had a time delay in one channel and a second coincidence detector operated with no time delays. Other experiments involve observations to rule out the possibility that the detectors

  2. Fertilizer Experiments with Cotton. 

    E-print Network

    Reynolds, E. B. (Elbert Brunner)

    1932-01-01

    LIBRARY. A & M COLLEGE, CAMPUS I TEXAS AGRICULTURAL EXPERIMENT STATION A. B. CONNER, DIRECTOR COLLEGE STATION, BRAZOS COUNTY, TEXAS BULLETIN NO. 469 DIVISION OF AGRONOMY Fertilizer Experiments with Cotton AGRICULTURAL AND MECHANICAL COLLEGE... of seven years experiments with fertilizers on cotton at Troup, Nacogdoches, Angleton, College Station, Beeville, Tem- ple, and Denton, Texas, are reported in this Bulletin. The Kirvin fine sandy loam at Troup and the Nacogdoches and Ruston fine sandy...

  3. Microgravity Experiments On Animals

    NASA Technical Reports Server (NTRS)

    Dalton, B. P.; Leon, H.; Hogan, R.; Clarke, B.; Tollinger, D.

    1991-01-01

    Paper describes experiments on animal subjects planned for Spacelab Life Sciences 1 mission. Laboratory equipment evaluated, and physiological experiments performed. Represents first step in establishing technology for maintaining and manipulating rodents, nonhuman primates, amphibians, and plants during space flight without jeopardizing crew's environment. In addition, experiments focus on effects of microgravity on cardiopulmonary, cardiovascular, and musculoskeletal systems; on regulation of volume of blood and production of red blood cells; and on calcium metabolism and gravity receptors.

  4. Chemiluminescence: An Illuminating Experiment

    ERIC Educational Resources Information Center

    Gafney, Harry D.; Adamson, Arthur W.

    1975-01-01

    Describes an experiment in which luminescence is observed during a reaction between sodium borohydride and trisbipyridalruthenium (III). Includes a discussion of the theory of chemiluminescence. (MLH)

  5. SEDS experiment design definition

    NASA Technical Reports Server (NTRS)

    Carroll, Joseph A.; Alexander, Charles M.; Oldson, John C.

    1990-01-01

    The Small Expendable-tether Deployment System (SEDS) was developed to design, build, integrate, fly, and safely deploy and release an expendable tether. A suitable concept for an on-orbit test of SEDS was developed. The following tasks were performed: (1) Define experiment objectives and requirements; (2) Define experiment concepts to reach those objectives; (3) Support NASA in experiment concept selection and definition; (4) Perform analyses and tests of SEDS hardware; (5) Refine the selected SEDS experiment concept; and (6) Support interactive SEDS system definition process. Results and conclusions are given.

  6. Future Neutrino Experiments

    SciTech Connect

    Fleming, B. T. [Physics Department, Yale University, New Haven, CT 60510 (United States)

    2009-12-17

    There are a number of future neutrino experiments addressing fundamental questions about the neutrino and about what the neutrino can tell us about the universe. A class of these experiments are long baseline neutrino oscillation v{sub e} appearance searches which can measure the final unknowns of the 3x3 neutrino mixing matrix and look for CP violation in the neutrino sector. The massive detectors needed for these experiments can also search for proton decay and measure extra-terrestrial neutrino sources. There are a number of efforts worldwide to launch these experiments. These efforts, with a focus on US plans, are described.

  7. Auroral perturbation experiments

    NASA Astrophysics Data System (ADS)

    Yau, A. W.; Whalen, B. A.

    Published data from active space experiments in which the auroral ionosphere is perturbed by the release of neutral gas are compiled in extensive graphs and analyzed. Consideration is given to thermite neutral and ion tracer experiments, shaped-charge releases, critical-velocity releases, negative-ion experiments, and plasma-depletion experiments. It is concluded that field-aligned currents can drive topside ionospheric instabilities (which then stimulate particle acceleration), and that auroral arc formation is significantly influenced by ionospheric conductivity. Greater conductivity within the auroral arcs is shown to increase particle precipitation via a feedback mechanism.

  8. [Near death experiences].

    PubMed

    Rubia Vila, Francisco José

    2012-01-01

    Near Death Experiences are those accounted by people who after being clinically dead return to life spontaneously or after reanimation. These experiences have been used traditionally to support the belief in the existence of the soul and of life after death. However, today neuroscience tries to explain these experiences from the scientific point of view, i.e. explaining them based on their brain substrates. Their resemblance to mystic experiences and to altered states of consciousness seems to indicate that they may be produced by hyperactivity of limbic structures caused by anoxia or hypercapnia. PMID:24294729

  9. Exploring Sensory Neuroscience Through Experience and Experiment

    PubMed Central

    Wyttenbach, Robert A.

    2012-01-01

    Many phenomena that we take for granted are illusions — color and motion on a TV or computer monitor, for example, or the impression of space in a stereo music recording. Even the stable image that we perceive when looking directly at the real world is illusory. One of the important lessons from sensory neuroscience is that our perception of the world is constructed rather than received. Sensory illusions effectively capture student interest, but how do you then move on to substantive discussion of neuroscience? This article illustrates several illusions, attempts to connect them to neuroscience, and shows how students can explore and experiment with them. Even when (as is often the case) there is no agreed-upon mechanistic explanation for an illusion, students can form hypotheses and test them by manipulating stimuli and measuring their effects. In effect, students can experiment with illusions using themselves as subjects. PMID:23493966

  10. The Group Experience

    ERIC Educational Resources Information Center

    Wadsworth, John

    2008-01-01

    Knowledge of group dynamics and leadership activities is a component of the CORE Standards for the Master's degree curriculum in Rehabilitation Counseling. A group experience is often included as a learning activity in rehabilitation counselor education curricula as an instructional method of imparting knowledge of group dynamics. Group experience

  11. Social Balance Experiment

    NSDL National Science Digital Library

    This is the entry page for participation in the Social Balance Experiment. In this experiment, participants are asked to imagine that they are in a situation in which they have one of five feelings (love, like, neutral, dislike or hate) toward another person named Bill.

  12. Numerical Memory Experiment

    NSDL National Science Digital Library

    This is the entry page for the Numerical Memory Experiment. This Numerical Memory experiment employs a similar format to Digit Span tasks found in assessment instruments, comparing the individual's short-term memory for digits presented in an auditory vs. visual format.

  13. The Skylab experiment program.

    NASA Technical Reports Server (NTRS)

    Schneider, W. C.; Green, W. D., Jr.

    1972-01-01

    Description of planned Skylab experiments in the general fields of life sciences, solar physics, earth observations, astrophysics, engineering, and technology. Each experiment is outlined in terms of its specific purpose, supporting hardware, relevant functions to be performed by an astronaut, and data recovery measures. Major support facilities described include the scientific airlock, the articulated mirror system, the extendable boom, and the film vault.

  14. The Student Experience.

    ERIC Educational Resources Information Center

    Haselgrove, Susanne, Ed.

    This collection of papers discusses the experience of students in the United Kingdom's new, mass higher education system. The papers are viewed as dispatches from the "front line" rather than conventional analyses by education researchers. The organization of the papers mirrors the stages of students' experience of higher education--getting in,…

  15. Experiment design Conditions

    E-print Network

    Beckhaus, Steffi

    Experiment design Conditions: Motor control vs. dark Lshape/HMD Empty physical room vs. empty Strichproben) "Video ergo sum" ist ein solches Experiment, bei dem in einem Head Mounted Display (HMD) der System (LShape), hochauflösendes __HMD (nVisor ST) computergenerierte Avatare als virtuelle

  16. MSFC Skylab corollary experiments

    NASA Technical Reports Server (NTRS)

    1974-01-01

    The evolution of the development and integration of Skylab experiments from initial concepts through mission operations is documented. All experiment systems are covered as well as management controls which were developed and exercised to assure acceptable operational capability and optimize data acquisition for final scientific results.

  17. The Shared Experience.

    ERIC Educational Resources Information Center

    MacKinlay, Eileen

    The writing of students at colleges of education about their teaching experiences and the writing done for them by children in infant and junior schools comprise this account of attempts to answer such questions as "What makes children want to write?" and "What is the relation between a writer's experience and imagination?" Excerpts from college…

  18. Real-World Experiences

    ERIC Educational Resources Information Center

    Borja, Rhea R.

    2006-01-01

    This article presents IISME, a U.S. program that can give educators a real-world experience and that can deepen their subject-matter knowledge. It also presents the experiences of some teachers who are into this program. IISME's summer-fellowship program started out with 40 teachers and 12 companies. The group's growth picked up in 2001, when it…

  19. Notes on Experiments.

    ERIC Educational Resources Information Center

    Physics Education, 1980

    1980-01-01

    Describes briefly three experiments, which are presented by three physics teachers to share their ideas with other teachers and readers. These experiments are: (1) a simple hazemeter for window pollution assessment; (2) the speed of light; and (3) the ball-bearing electric motor. (HM)

  20. Die Coin Experiment

    NSDL National Science Digital Library

    Kyle Siegrist

    This resource consists of a Java applet and expository text. The applet simulates the experiment of rolling a die and then tossing a coin the number of times shown on the die. The die distribution and the probability of heads can be specified. The applet illustrates a two-stage experiment.

  1. Buffon's Needle Experiment

    NSDL National Science Digital Library

    Kyle Siegrist

    This resource consists of a Java applet and expository text. The applet simulates Buffon's needle experiment and the corresponding approximation of pi. The event of interest is that the needle crosses a crack. The length of the needle can be varied. The applet illustrates a random experiment, the sample space, random variables, probability, and relative frequency.

  2. Double Chooz neutrino experiment

    Microsoft Academic Search

    Carmen Palomares

    2009-01-01

    The Double Chooz experiment will use the electron antineutrinos produced by the Chooz nuclear power station to search for a non-vanishing value of the Theta_13 neutrino mixing angle. Double Chooz will be the first of a new generation of neutrino experiments using identical detectors at different distances from the neutrino source to reduce the systematic errors due to the uncertainties

  3. Summer Research Experiences

    NSDL National Science Digital Library

    Susan Musante (American Institute of Biological Sciences; )

    2006-07-01

    From the pages of magazine, the online version of our education column in BioScience provides educators with updates in science education, examples of successful initiatives to transform biology teaching, and new ways of improving student understanding. This article describes the experiences of two teachers and their mentors who participated in the National Science Foundation's Research Experiences for Teachers program.

  4. Shusterman on Somatic Experience

    ERIC Educational Resources Information Center

    Maattanen, Pentti

    2010-01-01

    Richard Shusterman's "Body Consciousness" aims at formulating a theory of somaesthetics and somatic experience. There has indeed been a growing interest in the role of the body in experience. Shusterman examines the arguments of six important writers who have been influential in this discussion. The emphasis on the body is natural for a…

  5. Undergraduate Infrared Spectroscopy Experiments.

    ERIC Educational Resources Information Center

    MacCarthy, Patrick; Bowman, Susan J.

    1982-01-01

    Highlights procedures and results of an experiment using atomic absorption spectroscope to illustrate a fundamental chemical concept. The experiment demonstrates the dependence of the solubility product of lead sulfate on ionic strength in the presence of a slight excess of anion. (Author/JN)

  6. Cibola flight experiment

    Microsoft Academic Search

    D. Roussel-Dupre; M. P. Caffrey

    2004-01-01

    Los Alamos National Laboratory is building the Cibola Flight Experiment (CFE), a reconfigurable processor payload intended for a Low Earth Orbit system. It will survey portions of the VHF and UHF radio spectra. The experiment uses networks of reprogrammable, Field Programmable Gate Arrays (FPGAs) to process the received signals for ionospheric and lightning studies. The objective is to validate the

  7. Measuring mediated communication experience

    Microsoft Academic Search

    Viljakaisa Aaltonen; Jari Takatalo; Miikka Lehtonen; Göte Nyman; Martin Schrader

    2009-01-01

    A great deal of our daily communication is technology-mediated and ranges from phone discussions to negotiations in sophisticated video conferences. We studied the mediated communication interaction and experience in three experimental setups: high quality video conferencing, Skype calls with webcam and audio conferencing. The communication experience was studied with a statistically developed five-dimensional measure. The differences were analysed with a

  8. Aeroassist Flight Experiment (AFE)

    NASA Technical Reports Server (NTRS)

    Siemers, Paul M., III

    1988-01-01

    Information is given in viewgraph form on the Aeroassist Flight Experiment (AFE), an experiment with the objective of investigating critical vehicle design and environmental technologies applicable to the design of aeroassisted space transfer vehicles. Information is given on design, simulation, flight regime, mission requirements and objectives, instrumentation, and the project schedule.

  9. Earthquake Effects and Experiences

    NSDL National Science Digital Library

    This portion of the United States Geological Survey's (USGS) frequently-asked-questions feature on earthquakes addresses what individuals might actually experience during an earthquake. Topics include earthquake motion (rolling or shaking), earthquake effects (ground shaking, surface faulting, ground failure, etc.), earthquake magnitude, what an earthquake feels like, and others. There are also links to additional resources on earthquake effects and experiences.

  10. Design Of Experiments: Overview

    Microsoft Academic Search

    Jack P. C. Kleijnen

    2008-01-01

    Design Of Experiments (DOE) is needed for experiments with real-life systems, and with either deterministic or ran- dom simulation models. This contribution discusses the different types of DOE for these three domains, but fo- cusses on random simulation. DOE may have two goals: sensitivity analysis and optimization. This contribution starts with classic DOE including 2k p and Central Composite Designs

  11. The Jumping Ring Experiment

    ERIC Educational Resources Information Center

    Baylie, M.; Ford, P. J.; Mathlin, G. P.; Palmer, C.

    2009-01-01

    The jumping ring experiment has become central to liquid nitrogen shows given as part of the outreach and open day activities carried out within the University of Bath. The basic principles of the experiment are described as well as the effect of changing the geometry of the rings and their metallurgical state. In general, aluminium rings are…

  12. Conference: Synergy Between Experiment

    E-print Network

    Heller, Eric

    An NNIN/C Conference: Synergy Between Experiment and Computation in Energy ­ Looking to 2030. Yu on rapidly developing areas of nanoscale computation, will hold a conference on energy research, experiment and computation. The conference will be based around the four focus topics: fuel cells, catalysis, self

  13. Dulye Leadership Experience The Ultimate Professional Development Experience

    E-print Network

    Crowston, Kevin

    Dulye Leadership Experience The Ultimate Professional Development Experience: Dulye Leadership Experience Do YOU have what it takes to join the team? Find out more at dle.dulye.com Facebook: https://www.facebook.com/DulyeLeadershipExperience Twitter: DLE4SU #12;Dulye Leadership Experience Program Overview Dulye Leadership Experience The Dulye

  14. Extravehicular activity welding experiment

    NASA Technical Reports Server (NTRS)

    Watson, J. Kevin

    1989-01-01

    The In-Space Technology Experiments Program (INSTEP) provides an opportunity to explore the many critical questions which can only be answered by experimentation in space. The objective of the Extravehicular Activity Welding Experiment definition project was to define the requirements for a spaceflight experiment to evaluate the feasibility of performing manual welding tasks during EVA. Consideration was given to experiment design, work station design, welding hardware design, payload integration requirements, and human factors (including safety). The results of this effort are presented. Included are the specific objectives of the flight test, details of the tasks which will generate the required data, and a description of the equipment which will be needed to support the tasks. Work station requirements are addressed as are human factors, STS integration procedures and, most importantly, safety considerations. A preliminary estimate of the cost and the schedule for completion of the experiment through flight and postflight analysis are given.

  15. Space Experiment Module (SEM)

    NASA Technical Reports Server (NTRS)

    Brodell, Charles L.

    1999-01-01

    The Space Experiment Module (SEM) Program is an education initiative sponsored by the National Aeronautics and Space Administration (NASA) Shuttle Small Payloads Project. The program provides nationwide educational access to space for Kindergarten through University level students. The SEM program focuses on the science of zero-gravity and microgravity. Within the program, NASA provides small containers or "modules" for students to fly experiments on the Space Shuttle. The experiments are created, designed, built, and implemented by students with teacher and/or mentor guidance. Student experiment modules are flown in a "carrier" which resides in the cargo bay of the Space Shuttle. The carrier supplies power to, and the means to control and collect data from each experiment.

  16. Health education telecommunications experiment

    NASA Technical Reports Server (NTRS)

    Whalen, A. A.

    1975-01-01

    The Health/Education Telecommunications Experiment (HET) was conducted jointly by NASA and HEW on NASA's ATS-6 communications satellite. This experiment actually consisted of six experiments testing health and education applications of a communication spacecraft producing a broadcast of color television directly from space to over 120 low-cost receivers located in remote rural areas throughout the U.S. (including Alaska). The experiments were conducted over the period from 2 July 1974 to 20 May 1975 and operated on an almost daily basis. The overall telecommunications system to support these experiments consisted of many elements: The ATS-6 spacecraft; five different types of earth stations consisting of 120 video receive terminals, 51 telephony tranceivers and eight video originating terminals of three different types. Actual performance of the equipment as measured in the field was shown to equal or exceed predicted values.

  17. Hadron production experiments

    E-print Network

    Boris A. Popov

    2012-12-05

    The HARP and NA61/SHINE hadroproduction experiments as well as their implications for neutrino physics are discussed. HARP measurements have already been used for predictions of neutrino beams in K2K and Mini-BooNE/SciBooNE experiments and are also being used to improve the atmospheric neutrino flux predictions and to help in the optimization of neutrino factory and super-beam designs. First measurements released recently by the NA61/SHINE experiment are of significant importance for a precise prediction of the J-PARC neutrino beam used for the T2K experiment. Both HARP and NA61/SHINE experiments provide also a large amount of input for validation and tuning of hadron production models in Monte-Carlo generators.

  18. Hadron production experiments

    NASA Astrophysics Data System (ADS)

    Popov, Boris A.

    2013-02-01

    The HARP and NA61/SHINE hadroproduction experiments as well as their implications for neutrino physics are discussed. HARP measurements have already been used for predictions of neutrino beams in K2K and MiniBooNE/SciBooNE experiments and are also being used to improve the atmospheric neutrino flux predictions and to help in the optimization of neutrino factory and super-beam designs. First measurements released recently by the NA61/SHINE experiment are of significant importance for a precise prediction of the J-PARC neutrino beam used for the T2K experiment. Both HARP and NA61/SHINE experiments provide also a large amount of input for validation and tuning of hadron production models in Monte-Carlo generators.

  19. USML-1 Glovebox experiments

    NASA Technical Reports Server (NTRS)

    Naumann, Robert J.

    1995-01-01

    This report covers the development of and results from three experiments that were flown in the Materials Science Glovebox on USML-1: Marangoni convection in Closed Containers (MCCC), Double Float Zone (DFZ), and Fiber Pulling in Microgravity (FPM). The Glovebox provided a convenient, low cost method for doing simple 'try and see' experiments that could test new concepts or elucidate microgravity phenomena. Since the Glovebox provided essentially one (or possibly two levels of confinement, many of the stringent verification and test requirements on the experiment apparatus could be relaxed and a streamlined test and verification plan for flight qualification could be implemented. Furthermore, the experiments were contained in their own carrying cases whose external configurations could be identified early in the integration sequence for stowage considerations while delivery of the actual experiment apparatus could be postponed until only a few months before flight. This minimized the time fluids must be contained and reduced the possibility of corrosive reactions that could ruin the experiment. In many respects, this exercise was as much about developing a simpler, cheaper way of doing crew-assisted science as it was about the actual scientific accomplishments of the individual experiments. The Marangoni Convection in Closed Containers experiment was designed to study the effects of a void space in a simulated Bridgman crystal growth configuration and to determine if surface tension driven convective flows that may result from thermal gradients along any free surfaces could affect the solidification process. The Fiber Pulling in Microgravity experiment sought to separate the role of gravity drainage from capillarity effects in the break-up of slender cylindrical liquid columns. The Stability of a Double Float Zone experiment explored the feasibility of a quasi-containerless process in which a solidifying material is suspended by two liquid bridges of its own melt.

  20. LDR structural experiment definition

    NASA Technical Reports Server (NTRS)

    Russell, Richard A.; Gates, Richard M.

    1988-01-01

    A study was performed to develop the definition of a structural flight experiment for a large precision segmented reflector that would utilize the Space Station. The objective of the study was to use the Large Deployable Reflector (LDR) baseline configuration for focusing on experiment definition activity which would identify the Space Station accommodation requirements and interface constraints. Results of the study defined three Space Station based experiments to demonstrate the technologies needed for an LDR type structure. The basic experiment configurations are the same as the JPL baseline except that the primary mirror truss is 10 meters in diameter instead of 20. The primary objectives of the first experiment are to construct the primary mirror support truss and to determine its structural and thermal characteristics. Addition of the optical bench, thermal shield and primary mirror segments and alignment of the optical components occur on the second experiment. The structure will then be moved to the payload pointing system for pointing, optical control and scientific optical measurement for the third experiment.

  1. Radiochemical solar neutrino experiments

    E-print Network

    V. N. Gavrin; B. T. Cleveland

    2007-03-06

    Radiochemical experiments have been crucial to solar neutrino research. Even today, they provide the only direct measurement of the rate of the proton-proton fusion reaction, p + p --> d + e^+ + nu_e, which generates most of the Sun's energy. We first give a little history of radiochemical solar neutrino experiments with emphasis on the gallium experiment SAGE -- the only currently operating detector of this type. The combined result of all data from the Ga experiments is a capture rate of 67.6 +/- 3.7 SNU. For comparison to theory, we use the calculated flux at the Sun from a standard solar model, take into account neutrino propagation from the Sun to the Earth and the results of neutrino source experiments with Ga, and obtain 67.3 ^{+3.9}_{-3.5} SNU. Using the data from all solar neutrino experiments we calculate an electron neutrino pp flux at the earth of (3.41 ^{+0.76}_{-0.77}) x 10^{10}/(cm^2-s), which agrees well with the prediction from a detailed solar model of (3.30 ^{+0.13} _{-0.14}) x 10^{10}/(cm^2-s). Four tests of the Ga experiments have been carried out with very intense reactor-produced neutrino sources and the ratio of observed to calculated rates is 0.88 +/- 0.05. One explanation for this unexpectedly low result is that the cross section for neutrino capture by the two lowest-lying excited states in 71Ge has been overestimated. We end with consideration of possible time variation in the Ga experiments and an enumeration of other possible radiochemical experiments that might have been.

  2. Advanced biostack experiment

    NASA Technical Reports Server (NTRS)

    Buecker, H.

    1981-01-01

    The Advanced Biostack Experiment is described. The objectives are: (1) to confirm, complement, and enlarge the information obtained from the previous experiments by applying improved and advanced methods of localization and physical and biological evaluation, performing advanced experiments based on these data, and including additional biological specimens and additional radiation detectors; (2) to determine the biological importance of nuclear disintegration stars; (3) to determine the interference of HZE particle induced effects with those of other space flight factors (e.g., weightlessness); and (4) to determine the distribution of HZE particles and of disintegration stars at different locations inside the module and on the pallet.

  3. Industrial application experiment series

    NASA Astrophysics Data System (ADS)

    Bluhm, S. A.

    1981-05-01

    Two procurements within the Industrial Application Experiment Series of the Thermal Power Systems Project are discussed. The first procurement, initiated in April 1980, resulted in an award to the Applied Concepts Corporation for the Capital Concrete Experiment: two Fresnel concentrating collectors will be evaluated in single-unit installations at the Jet Propulsion Laboratory Parabolic Dish Test Site and at Capitol Concrete Products, Topeka, Kansas. The second procurement, initiated in March 1981, is titled, "Thermal System Engineering Experiment B." The objective of the procurement is the rapid deployment of developed parabolic dish collectors.

  4. Reactor Neutrino Experiments

    E-print Network

    Jun Cao

    2007-12-06

    Precisely measuring $\\theta_{13}$ is one of the highest priority in neutrino oscillation study. Reactor experiments can cleanly determine $\\theta_{13}$. Past reactor neutrino experiments are reviewed and status of next precision $\\theta_{13}$ experiments are presented. Daya Bay is designed to measure $\\sin^22\\theta_{13}$ to better than 0.01 and Double Chooz and RENO are designed to measure it to 0.02-0.03. All are heading to full operation in 2010. Recent improvements in neutrino moment measurement are also briefed.

  5. Public Goods Experiment

    NSDL National Science Digital Library

    Todd Swarthout

    In this experiment, students must decide how to divide their "endowment" of a good between private consumption and a public good. The private consumption provides a benefit (earnings) to only the individual and the public good provides a benefit to each person in the group, even those who do not contribute to the public good. This hand-run experiment is suitable for use in small classes in the range of 5 to 40 students. Some variations on this basic experiment are also described.

  6. Notes on Experiments.

    ERIC Educational Resources Information Center

    Physics Education, 1989

    1989-01-01

    Introduced are two experiments: radon detection method shows real data using vacuum cleaner, soft toilet paper, and Geiger-Muller tube; critical potentials measurement describes the operation of Teltron tube with VELA. (YP)

  7. Notes on Experiments.

    ERIC Educational Resources Information Center

    Physics Education, 1988

    1988-01-01

    Describes four physics experiments including "Investigation of Box Resonances Using a Micro"; "A Direct Reading Wattmeter, DC or AC"; "Exercises in the Application of Ohm's Law"; and "Hysteresis on Gas Discharges." Discusses procedures, instrumentation, and analysis in each example. (CW)

  8. Notes on Experiments.

    ERIC Educational Resources Information Center

    Physics Education, 1979

    1979-01-01

    Explains how to demonstrate the following: the hysteresis effect and the existence of domains in Rochelle salt (sodium potassium tartrate); diffraction experiments using a slide with multiple slits; and an analogue technique for learning terminal velocity. (GA)

  9. An experiment in regelation

    Microsoft Academic Search

    D. W. Townsend; R. P. Vickery

    1967-01-01

    An experiment in regelation has been carried out using objects of different geometries and thermal properties. A comparison of results and theory indicates that the presently accepted ideas are inadequate.

  10. Experiments in Animal Behavior

    ERIC Educational Resources Information Center

    Polt, James M.

    1971-01-01

    Describes experiments in conditioning, sensory processes, social behavior, imprinting, innate preferences for color and form, and discrimination learning suitable for secondary school students. Mealworms, crickets, and chicks are used as subjects. (AL)

  11. Experimenting with Detergents

    ERIC Educational Resources Information Center

    Mitchell, Gail; Phillips, Donald B.

    1977-01-01

    Lists materials and procedures for experimenting with detergents. Included are methods for determination of the densities of dry detergents, ph values of detergent solutions, and a discussion of the ability of detergents to remove iodine stains from cloth. (CS)

  12. Germany's Solar Experiment

    NSDL National Science Digital Library

    NOVA

    This NOVA video podcast is about Germany's solar experiment. Munich's solar panel farm lines the Autobahn and countryside in a massive effort to prove solar's feasibility as a practical renewable energy source.

  13. Notes on Experiments.

    ERIC Educational Resources Information Center

    Physics Education, 1988

    1988-01-01

    Describes three experiments: (1) "Liquid Flow from Orifices"; (2) "Microcomputer-Controlled Investigation of Battery Discharge and Recovery"; and (3) "Measurement of the Speed of Sound." Drawings and diagrams accompany each. (RT)

  14. Foraging Experiences with Children

    ERIC Educational Resources Information Center

    Russell, Helen Ross

    1976-01-01

    Provided are foraging experiences and wild foods information for utilization in the urban school curriculum. Food uses are detailed for roses, dandelions, wild onions, acorns, cattails, violets and mints. (BT)

  15. The monsoon experiment MONEX

    NASA Technical Reports Server (NTRS)

    Das, P. K.

    1979-01-01

    The effects of monsoons in different parts of the world on the Earth's atmosphere were studied by MONEX, India's Monsoon Experiment program. Data were gathered from meteorological satellites, sounding rockets, aircraft, land and shipborne stations.

  16. The Double Chooz Experiment

    SciTech Connect

    Dracos, Marcos [IPHC, Universite de Strasbourg, CNRS/IN2P3, F-67037 Strasbourg (France)

    2011-10-06

    The Double Chooz reactor neutrino experiment aims at observing the last neutrino oscillation not yet observed and at measuring the corresponding mixing angle {theta}{sub 13}. A relatively big value of this angle will allow the measurement of CP violation in the leptonic sector by the next neutrino oscillation experiments. This disappearance experiment will precisely count the number of anti-neutrinos produced by the two nuclear reactors of the Chooz nuclear plant in France. In a first stage, Double Chooz will only use a far detector which could allow to give a sin{sup 2}(2{theta}{sub 13}) low limit of 0.06. Two years after, a near detector, identical to the far one, will be in operation and allow us to push this limit down to 0.03 by reducing the systematic errors. The status of this experiment is presented in this paper.

  17. Millikan's Oil Drop Experiment

    NSDL National Science Digital Library

    Mr. Tony DiMauro

    2009-01-12

    This is a Keynote Presentation exported as a clickable quicktime movie. This presentation develops Millikan's Oil Drop experiment. The presentation is animated and the learner or Instructor can click their way through the presenation. The mathematical theory is fully developed.

  18. Field experiments in retailing

    E-print Network

    Fong, Nathan Minsheng

    2011-01-01

    This dissertation consists of two essays on tactical issues in retailing. The first essay compares the price sensitivity of private label and national brand products. A large-scale field experiment shows that private label ...

  19. Experiments on atmospheric processes

    NASA Technical Reports Server (NTRS)

    Vaughan, W. W.

    1977-01-01

    Spacelab technology is examined as applied to the observation of the earth's weather patterns, composition, thermodynamics, and kinematics. An atmospheric cloud physics laboratory and a geophysical fluid flow cell are individually outlined as planned payload experiment efforts.

  20. The Value of Experience

    ERIC Educational Resources Information Center

    Weiss, Stefanie C.; Gomperts, John S.

    2005-01-01

    Older volunteers are helping urban students in developing the confidence and skills to succeed. Older adults, with their life experience and strong commitment to social service, can make a special contribution in underfunded and understaffed urban schools.

  1. Experiments on ferrimagnetism

    NASA Astrophysics Data System (ADS)

    Kraftmakher, Yaakov

    2013-03-01

    Ferrimagnetism undoubtedly deserves a proper place in the undergraduate laboratory on electricity and magnetism. Four student experiments on ferrimagnetism are considered: (i) the hysteresis loops and permeability of a ‘soft’ ferrite; (ii) the differential permeability versus a dc bias; (iii) the frequency dependence of the complex permeability and (iv) the electromagnetic interference suppression by ferrite chokes and beads. Two ferrite cores taken off a low-frequency choke and a power cord are used. The measurements are simple and straightforward and show the important properties of ferrites and their applications. The values of the permeability of the ferrite core determined in experiments (i)-(iii) are in reasonable agreement. The frequency dependence of the complex permeability of the ferrites is similar to that given by the manufacturers. The capability of absorbing electromagnetic waves in a definite frequency range shown in experiment (iv) demonstrates one of the principles of Stealth technology. The equipment necessary for the experiments can be found in many student laboratories.

  2. Dihalocarbene Insertion Experiment

    ERIC Educational Resources Information Center

    Goh, S. H.

    1975-01-01

    Describes the insertion reaction using the insertion of carbenes into carbon-hydrogen bonds as an example. Outlines an experiment that will illustrate dihalocarbene insertions into diisopropyl ether. (GS)

  3. Celestial mechanics experiment

    NASA Technical Reports Server (NTRS)

    Lorell, J.; Anderson, J. D.; Jordan, J. F.; Reasenberg, R. D.; Shapiro, I. I.

    1973-01-01

    The efforts and accomplishments of the CME Team are summarized. The objectives and experiment status, gravity field of Mars, test of general relativity, and the generation of normal points are discussed.

  4. Experiment-o-mania

    NASA Astrophysics Data System (ADS)

    Drndarski, Marina

    2015-04-01

    Every 21st century student is expected to develop science literacy skills. As this is not part of Serbian national curriculum yet, we decided to introduce it with this project. Experiment-o-mania provides students to experience science in different and exciting way. It makes opportunity for personalized learning offering space and time to ask (why, where, how, what if) and to try. Therefore, we empower young people with skills of experimenting, and they love science back. They ask questions, make hypothesis, make problems and solve them, make mistakes, discuss about the results. Subsequently this raises the students' interest for school curriculum. This vision of science teaching is associated with inquiry-based learning. Experiment-o-mania is the unique and recognizable teaching methodology for the elementary school Drinka Pavlovi?, Belgrade, Serbia. Experiment-o-mania implies activities throughout the school year. They are held on extra class sessions, through science experiments, science projects or preparations for School's Days of science. Students learn to ask questions, make observations, classify data, communicate ideas, conduct experiments, analyse results and make conclusions. All science teachers participate in designing activities and experiments for students in Experiment-o-mania teaching method. But they are not alone. Teacher of fine arts, English teachers and others also take part. Students have their representatives in this team, too. This is a good way to blend knowledge among different school subject and popularize science in general. All the experiments are age appropriate and related to real life situations, local community, society and the world. We explore Fibonacci's arrays, saving energy, solar power, climate change, environmental problems, pollution, daily life situations in the country or worldwide. We introduce great scientists as Nikola Tesla, Milutin Milankovi? and sir Isaac Newton. We celebrate all relevant international days, weeks, months or years (this year, 2015. the students will prepare opera science for celebrate the International Year of Light and International Year of Soils). Experiment-o-mania makes science teaching and learning exciting for teachers as well as for students. The acquisition of this kind of teaching method (and its frequency) empowers students and become self-regulated learners, independent, to creatively solve problems, to innovate, to truly understand and appreciate science and to better understand themselves and the world around them.

  5. Object Location Experiment

    NSDL National Science Digital Library

    This is the entry page for the Object Location Experiment. The experiment begins with a description of the object location memory task that the participants will complete. Participants learn that they will study an array of objects for a designated period of time; the array of objects will then disappear; and then the array of objects will reappear, but some of the objects will have exchanged positions.

  6. Ideas and Experience

    E-print Network

    Tuedio, Jim

    terminology should be understood. II What we need to consider now is Husserl's claim that experience is Evidenz. As I suggested in my opening, Kohak presents a lucid exposition of the Husserlean project, but fails to extend any critical remarks. Yet... as I also remarked, his exposition is so lucid that the obvious guestions needing to be asked of Husserl rise into clear view. In turning to a characterization of Kohak's presentation of the Husserlean claim that experience is Evidenz, I hope...

  7. Surface electrical properties experiment

    USGS Publications Warehouse

    Simmons, Gene; Strangway, David; Annan, Peter; Baker, Richard G.; Bannister, Lawrence; Brown, Raymon; Cooper, William; Cubley, Dean; deBettencourt, Joseph; England, Anthony W.; Groener, John; Kong, Jin-Au; LaTorraca, Gerald; Meyer, James; Nanda, Ved; Redman, David; Rossiter, James; Tsang, Leung; Urner, Joseph; Watts, Raymond

    1973-01-01

    The surface electrical properties (SEP) experiment was used to explore the subsurface material of the Apollo 17 landing site by means of electromagnetic radiation. The experiment was designed to detect electrical layering, discrete scattering bodies, and the possible presence of water. From the analysis of the data, it was expected that values of the electrical properties (dielectric constant and loss tangent) of lunar material in situ would be obtained.

  8. CANDOS EXPERIMENT OVERVIEW

    Microsoft Academic Search

    David J. Zillig

    The Communications and Navigation Demonstration On Shuttle (CANDOS) experiment will be onboard STS-107 as part of the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) HitchHiker Payload. The flight hardware consists of a first generation Low Power Transceiver (LPT) integrated with a commercial processor board functioning as the flight computer, along with an S-Band High Gain Transmit Antenna,

  9. Coin Die Experiment

    NSDL National Science Digital Library

    Kyle Siegrist

    This resource consists of a Java applet and expository text. The applet is a simulation of the experiment that consists of tossing a coin and then rolling either a red die or a green die, depending on the outcome of the coin toss. The probability of heads and the distributions of the two dice can be specified. The applet illustrates a two-stage experiment.

  10. The Double Chooz Experiment

    Microsoft Academic Search

    Patrick Pfahler

    2012-01-01

    Double Chooz is a reactor ??e-disappearance experiment situated at the commercial nuclear power plant of Chooz in northern France. The experiment aims for the revelation of the last unknown mixing angle ?13 as a part of the neutrino mixing matrix or the improvement of the upper limit for sin2(2?13), which is currently < 0.14 (90% CL). A newly developed gadolinium-loaded

  11. The Double Chooz Experiment

    Microsoft Academic Search

    D. Motta

    2006-01-01

    The measurement of the last undetermined neutrino mixing angle theta 13 is the main goal of the next generation of neutrino oscillation experiments. The present limit is dominated by the result of the Chooz experiment, which gives sin22 theta 13 lesssim 0.10-0.15 (depending on the true value of Delta m132), at 90 % confidence level. Double Chooz is a next

  12. Spacelab J experiment descriptions

    NASA Technical Reports Server (NTRS)

    Miller, Teresa Y. (editor)

    1993-01-01

    Brief descriptions of the experiment investigations for the Spacelab J Mission which was launched from the Kennedy Space Center aboard the Endeavour in Sept. 1992 are presented. Experiments cover the following: semiconductor crystals; single crystals; superconducting composite materials; crystal growth; bubble behavior in weightlessness; microgravity environment; health monitoring of Payload Specialists; cultured plant cells; effect of low gravity on calcium metabolism and bone formation; and circadian rhythm.

  13. The GLUEX Experiment

    SciTech Connect

    M.R. Shepherd

    2009-12-01

    The GLUEX experiment, to be constructed in the new Hall D at Jefferson Lab as part of the 12 GeV upgrade, will utilize a linearly polarized 9 GeV photon beam, produced via coherent bremsstrahlung radiation off of a diamond wafer, incident on a proton target to conduct a search for exotic hybrid mesons. A summary of the physics motivation for the experiment and the key factors that drive the design of the detector and beam line is presented.

  14. The MAJORANA Experiment

    SciTech Connect

    Aguayo Navarrete, Estanislao; Avignone, F. T.; Back, Henning O.; Barabash, Alexander S.; Bergevin, M.; Bertrand, F.; Boswell, M.; Brudanin, V.; Busch, Matthew; Chan, Yuen-Dat; Christofferson, Cabot-Ann; Collar, J. I.; Combs, Dustin C.; Cooper, R. J.; Detwiler, Jason A.; Doe, Peter J.; Efremenko, Yuri; Egorov, Viatcheslav; Ejiri, H.; Elliott, Steven R.; Esterline, James H.; Fast, James E.; Fields, N.; Finnerty, P.; Fraenkle, Florian; Gehman, Victor M.; Giovanetti, G. K.; Green, Matthew P.; Guiseppe, Vincente; Gusey, K.; Hallin, A. L.; Hazama, R.; Henning, R.; Hime, Andrew; Hoppe, Eric W.; Horton, Mark; Howard, Stanley; Howe, M. A.; Johnson, R. A.; Keeter, K.; Keillor, Martin E.; Keller, C.; Kephart, Jeremy D.; Kidd, Mary; Knecht, A.; Kochetov, Oleg; Konovalov, S.; Kouzes, Richard T.; LaFerriere, Brian D.; LaRoque, B. H.; Leon, Jonathan D.; Leviner, L.; Loach, J. C.; MacMullin, S.; Marino, Michael G.; Martin, R. D.; Mei, Dong-Ming; Merriman, Jason H.; Miller, M. L.; Mizouni, Leila; Nomachi, Masaharu; Orrell, John L.; Overman, Nicole R.; Phillips, D.; Poon, Alan; Perumpilly, Gopakumar; Prior, Gersende; Radford, D. C.; Rielage, Keith; Robertson, R. G. H.; Ronquest, M. C.; Schubert, Alexis G.; Shima, T.; Shirchenko, M.; Snavely, Kyle J.; Sobolev, V.; Steele, David; Strain, J.; Thomas, K.; Timkin, V.; Tornow, W.; Vanyushin, I.; Varner, R. L.; Vetter, Kai; Vorren, Kris R.; Wilkerson, John; Wolfe, B. A.; Yakushev, E.; Young, A.; Yu, Chang-Hong; Yumatov, Vladimir; Zhang, C.

    2011-10-01

    The Majorana collaboration is actively pursuing research and development aimed at a tonne-scale {sup 76}Ge neutrinoless double-beta decay ({beta}{beta}(0{nu})-decay) experiment. The current, primary focus is the construction of the Majorana Demonstrator experiment, an R and D effort that will field approximately 40 kg of germanium detectors with mixed enrichment levels. This article provides a status update on the construction of the Demonstrator.

  15. Experiments in Computing: A Survey

    PubMed Central

    Moisseinen, Nella

    2014-01-01

    Experiments play a central role in science. The role of experiments in computing is, however, unclear. Questions about the relevance of experiments in computing attracted little attention until the 1980s. As the discipline then saw a push towards experimental computer science, a variety of technically, theoretically, and empirically oriented views on experiments emerged. As a consequence of those debates, today's computing fields use experiments and experiment terminology in a variety of ways. This paper analyzes experimentation debates in computing. It presents five ways in which debaters have conceptualized experiments in computing: feasibility experiment, trial experiment, field experiment, comparison experiment, and controlled experiment. This paper has three aims: to clarify experiment terminology in computing; to contribute to disciplinary self-understanding of computing; and, due to computing's centrality in other fields, to promote understanding of experiments in modern science in general. PMID:24688404

  16. SummaryExperiments_June2002.doc 1 Summary for Experiments

    E-print Network

    Joseph, Daniel D.

    SummaryExperiments_June2002.doc 1 Summary for Experiments Bobby H. Yang (June, 2002) Experiment-1. Rotating experiments with high & low viscous Triton mixture under low filling level and relatively low of high-viscosity fluids and particles. Through experiments in partially filled horizontal Couette device

  17. Energy level properties of 4p4d, 4p4d4f, and 4p4d configurations of the W ion

    NASA Astrophysics Data System (ADS)

    Bogdanovich, P.; Kisielius, R.

    2014-11-01

    The ab initio quasirelativistic Hartree-Fock method developed specifically for the calculation of spectroscopic parameters of heavy atoms and highly charged ions was used to derive spectral data for the multicharged tungsten ion W35+. The configuration interaction method was applied to include the electron-correlation effects. The relativistic effects were taken into account in the Breit-Pauli approximation for quasirelativistic Hartree-Fock radial orbitals. The energy level spectra, radiative lifetimes ?, and Lande g-factors have been calculated for the 4p64d3, 4p64d24f, and 4p54d4 configurations of the W35+ ion.

  18. Teaching Issues and Experiments in Ecology: Experiments

    NSDL National Science Digital Library

    1969-12-31

    Teaching Issues and Experiments in Ecology (TIEE) is a collection of peer-reviewed, classroom/ field-tested teaching materials sponsored by the Ecological Society of America. Among these "scientifically sound and pedagogically innovative" teaching materials are a number of particularly well-designed ecology labs for field and classroom. As of February 2003, two of the seven labs on the Web site are complete and ready to download: Ecology of Habitat Contrasts and Environmental Correlates of Leaf Stomata Density. Both are designed for college level courses. Five other labs covering a range of ecology topics will eventually be available, and users may also take advantage of an earlier set of labs from 1993. The resources and materials provided for each lab are incredibly comprehensive. Suffice to say, this Web site is definitely one to bookmark and check frequently for updates.

  19. Understanding customer experience.

    PubMed

    Meyer, Christopher; Schwager, Andre

    2007-02-01

    Anyone who has signed up for cell phone service, attempted to claim a rebate, or navigated a call center has probably suffered from a company's apparent indifference to what should be its first concern: the customer experiences that culminate in either satisfaction or disappointment and defection. Customer experience is the subjective response customers have to direct or indirect contact with a company. It encompasses every aspect of an offering: customer care, advertising, packaging, features, ease of use, reliability. Customer experience is shaped by customers' expectations, which largely reflect previous experiences. Few CEOs would argue against the significance of customer experience or against measuring and analyzing it. But many don't appreciate how those activities differ from CRM or just how illuminating the data can be. For instance, the majority of the companies in a recent survey believed they have been providing "superior" experiences to customers, but most customers disagreed. The authors describe a customer experience management (CEM) process that involves three kinds of monitoring: past patterns (evaluating completed transactions), present patterns (tracking current relationships), and potential patterns (conducting inquiries in the hope of unveiling future opportunities). Data are collected at or about touch points through such methods as surveys, interviews, focus groups, and online forums. Companies need to involve every function in the effort, not just a single customer-facing group. The authors go on to illustrate how a cross-functional CEM system is created. With such a system, companies can discover which customers are prospects for growth and which require immediate intervention. PMID:17345685

  20. A Pharmacogenetics Service Experience for Pharmacy Students, Residents, and Fellows

    PubMed Central

    Drozda, Katarzyna; Labinov, Yana; Jiang, Ruixuan; Thomas, Margaret R.; Wong, Shan S.; Patel, Shitalben; Nutescu, Edith A.

    2013-01-01

    Objective. To utilize a comprehensive, pharmacist-led warfarin pharmacogenetics service to provide pharmacy students, residents, and fellows with clinical and research experiences involving genotype-guided therapy. Design. First-year (P1) through fourth-year (P4) pharmacy students, pharmacy residents, and pharmacy fellows participated in a newly implemented warfarin pharmacogenetics service in a hospital setting. Students, residents, and fellows provided genotype-guided dosing recommendations as part of clinical care, or analyzed samples and data collected from patients on the service for research purposes. Assessment. Students’, residents’, and fellows’ achievement of learning objectives was assessed using a checklist based on established core competencies in pharmacogenetics. The mean competency score of the students, residents, and fellows who completed a clinical and/or research experience with the service was 97% ±3%. Conclusion. A comprehensive warfarin pharmacogenetics service provided unique experiential and research opportunities for pharmacy students, residents, and fellows and sufficiently addressed a number of core competencies in pharmacogenetics. PMID:24159216

  1. National Flood Interoperability Experiment

    NASA Astrophysics Data System (ADS)

    Maidment, D. R.

    2014-12-01

    The National Flood Interoperability Experiment is led by the academic community in collaboration with the National Weather Service through the new National Water Center recently opened on the Tuscaloosa campus of the University of Alabama. The experiment will also involve the partners in IWRSS (Integrated Water Resources Science and Services), which include the USGS, the Corps of Engineers and FEMA. The experiment will address the following questions: (1) How can near-real-time hydrologic forecasting at high spatial resolution, covering the nation, be carried out using the NHDPlus or next generation geofabric (e.g. hillslope, watershed scales)? (2) How can this lead to improved emergency response and community resilience? (3) How can improved an improved interoperability framework support the first two goals and lead to sustained innovation in the research to operations process? The experiment will run from September 2014 through August 2015, in two phases. The mobilization phase from September 2014 until May 2015 will assemble the components of the interoperability framework. A Summer Institute to integrate the components will be held from June to August 2015 at the National Water Center involving faculty and students from the University of Alabama and other institutions coordinated by CUAHSI. It is intended that the insight that arises from this experiment will help lay the foundation for a new national scale, high spatial resolution, near-real-time hydrologic simulation system for the United States.

  2. Cryogenic fluid management experiment

    NASA Technical Reports Server (NTRS)

    Eberhardt, R. N.; Bailey, W. J.; Fester, D. A.

    1981-01-01

    The cryogenic fluid management experiment (CFME), designed to characterize subcritical liquid hydrogen storage and expulsion in the low-q space environment, is discussed. The experiment utilizes a fine mesh screen fluid management device to accomplish gas-free liquid expulsion and a thermodynamic vent system to intercept heat leak and control tank pressure. The experiment design evolved from a single flight prototype to provision for a multimission (up to 7) capability. A detailed design of the CFME, a dynamic test article, and dedicated ground support equipment were generated. All materials and parts were identified, and components were selected and specifications prepared. Long lead titanium pressurant spheres and the flight tape recorder and ground reproduce unit were procured. Experiment integration with the shuttle orbiter, Spacelab, and KSC ground operations was coordinated with the appropriate NASA centers, and experiment interfaces were defined. Phase 1 ground and flight safety reviews were conducted. Costs were estimated for fabrication and assembly of the CFME, which will become the storage and supply tank for a cryogenic fluid management facility to investigate fluid management in space.

  3. Molybdenum solar neutrino experiment

    SciTech Connect

    Wolfsberg, K.; Cowan, G.A.; Bryant, E.A.; Daniels, K.S.; Downey, S.W.; Haxton, W.C.; Niesen, V.G.; Nogar, N.S.; Miller, C.M.; Rokop, D.J.

    1984-01-01

    The goal of the molybdenum solar neutrino experiment is to deduce the /sup 8/B solar neutrino flux, averaged over the past several million years, from the concentration of /sup 98/Tc in a deeply buried molybdenum deposit. The experiment is important to an understanding of stellar processes because it will shed light on the reason for the discrepancy between theory and observation of the chlorine solar neutrino experiment. Possible reasons for the discrepancy may lie in the properties of neutrinos (neutrino oscillations or massive neutrinos) or in deficiencies of the standard solar model. The chlorine experiment only measures the /sup 8/B neutrino flux in current times and does not address possible temporal variations in the interior of the sun, which are also not considered in the standard model. In the molybdenum experiment, we plan to measure /sup 98/Tc (4.2 Myr), also produced by /sup 8/B neutrinos, and possibly /sup 97/Tc (2.6 Myr), produced by lower energy neutrinos.

  4. Laser-driven implosion experiments

    Microsoft Academic Search

    G H McCall

    1983-01-01

    A review of the experiments associated with laser-driven implosions is presented. These experiments include actual implosion experiments and experiments which simulate particular aspects of laser-driven implosions. Exploding pusher and isentropic implosion experiments are treated separately. Where possible a comparison of the data to analytic or computer simulation calculations is made. Exploding pusher analytic theory is shown to be qualitatively correct,

  5. AGS experiments, 1988, 1989, 1990

    SciTech Connect

    Depken, J.C.

    1991-04-01

    This report contains: experimental areas layout; table of beam parameters and fluxes; experiment schedule as run''; experiment long range schedule; a listing of experiments by number; two-page summaries of each experiment begin here, also ordered by number; publications of AGS experiments; and list of experimenters.

  6. AGS experiments: 1985, 1986, 1987

    SciTech Connect

    Depken, J.C.

    1987-01-01

    This report contains: Experimental areas layout, table of beam parameters and fluxes, experiment schedule ''as run,'' experiment long range schedule, a listing of experiments by number, two-page summaries of each experiment, also ordered by number, and publications of AGS experiments, 1982-1987.

  7. Experiments in mixed reality

    NASA Astrophysics Data System (ADS)

    Krum, David M.; Sadek, Ramy; Kohli, Luv; Olson, Logan; Bolas, Mark

    2010-01-01

    As part of the Institute for Creative Technologies and the School of Cinematic Arts at the University of Southern California, the Mixed Reality lab develops technologies and techniques for presenting realistic immersive training experiences. Such experiences typically place users within a complex ecology of social actors, physical objects, and collections of intents, motivations, relationships, and other psychological constructs. Currently, it remains infeasible to completely synthesize the interactivity and sensory signatures of such ecologies. For this reason, the lab advocates mixed reality methods for training and conducts experiments exploring such methods. Currently, the lab focuses on understanding and exploiting the elasticity of human perception with respect to representational differences between real and virtual environments. This paper presents an overview of three projects: techniques for redirected walking, displays for the representation of virtual humans, and audio processing to increase stress.

  8. Droplet Combustion Experiment movie

    NASA Technical Reports Server (NTRS)

    2003-01-01

    The Droplet Combustion Experiment (DCE) was designed to investigate the fundamental combustion aspects of single, isolated droplets under different pressures and ambient oxygen concentrations for a range of droplet sizes varying between 2 and 5 mm. The DCE principal investigator was Forman Williams, University of California, San Diego. The experiment was part of the space research investigations conducted during the Microgravity Science Laboratory-1 mission (STS-83, April 4-8 1997; the shortened mission was reflown as MSL-1R on STS-94). Advanced combustion experiments will be a part of investigations plarned for the International Space Station. (1.1 MB, 12-second MPEG, screen 320 x 240 pixels; downlinked video, higher quality not available)A still JPG composite of this movie is available at http://mix.msfc.nasa.gov/ABSTRACTS/MSFC-0300164.html.

  9. Droplet Combustion Experiment

    NASA Technical Reports Server (NTRS)

    2003-01-01

    The Droplet Combustion Experiment (DCE) was designed to investigate the fundamental combustion aspects of single, isolated droplets under different pressures and ambient oxygen concentrations for a range of droplet sizes varying between 2 and 5 mm. The DCE principal investigator was Forman Williams, University of California, San Diego. The experiment was part of the space research investigations conducted during the Microgravity Science Laboratory-1R mission (STS-94, July 1-17 1997). Advanced combustion experiments will be a part of investigations plarned for the International Space Station. (120KB JPEG, 655 x 736 pixels; downlinked video, higher quality not available) The MPG from which this composite was made is available at http://mix.msfc.nasa.gov/ABSTRACTS/MSFC-0300167.html.

  10. Future Experiments in Astrophysics

    NASA Technical Reports Server (NTRS)

    Krizmanic, John F.

    2002-01-01

    The measurement methodologies of astrophysics experiments reflect the enormous variation of the astrophysical radiation itself. The diverse nature of the astrophysical radiation, e.g. cosmic rays, electromagnetic radiation, and neutrinos, is further complicated by the enormous span in energy, from the 1.95 Kappa relic neutrino background to cosmic rays with energy greater than 10(exp 20)eV. The measurement of gravity waves and search for dark matter constituents are also of astrophysical interest. Thus, the experimental techniques employed to determine the energy of the incident particles are strongly dependent upon the specific particles and energy range to be measured. This paper summarizes some of the calorimetric methodologies and measurements planned by future astrophysics experiments. A focus will be placed on the measurement of higher energy astrophysical radiation. Specifically, future cosmic ray, gamma ray, and neutrino experiments will be discussed.

  11. The BLAST experiment

    NASA Astrophysics Data System (ADS)

    Hasell, D.; Akdogan, T.; Alarcon, R.; Bertozzi, W.; Booth, E.; Botto, T.; Calarco, J. R.; Clasie, B.; Crawford, C.; DeGrush, A.; Dow, K.; Dutta, D.; Farkhondeh, M.; Fatemi, R.; Filoti, O.; Franklin, W.; Gao, H.; Geis, E.; Gilad, S.; Hersman, W.; Holtrop, M.; Ihloff, E.; Karpius, P.; Kelsey, J.; Kohl, M.; Kolster, H.; Krause, S.; Lee, T.; Maschinot, A.; Matthews, J.; McIlhany, K.; Meitanis, N.; Milner, R.; Rapaport, J.; Redwine, R.; Seely, J.; Shinozaki, A.; Sindile, A.; Širca, S.; Smith, T.; Sobczynski, S.; Tanguay, M.; Tonguc, B.; Tschalaer, C.; Tsentalovich, E.; Turchinetz, W.; van den Brand, J. F. J.; van der Laan, J.; Wang, F.; Wise, T.; Xiao, Y.; Xu, W.; Zhang, C.; Zhou, Z.; Ziskin, V.; Zwart, T.

    2009-05-01

    The Bates large acceptance spectrometer toroid (BLAST) experiment was operated at the MIT-Bates Linear Accelerator Center from 2003 until 2005. The detector and experimental program were designed to study, in a systematic manner, the spin-dependent electromagnetic interaction in few-nucleon systems. As such the data will provide improved measurements for neutron, proton, and deuteron form factors. The data will also allow details of the reaction mechanism, such as the role of final state interactions, pion production, and resonances to be studied. The experiment used: a longitudinally polarized electron beam stored in the South Hall Storage Ring; a highly polarized, isotopically pure, internal gas target of hydrogen or deuterium provided by an atomic beam source; and a symmetric, general purpose detector based on a toroidal spectrometer with tracking, time-of-flight, Cherenkov, and neutron detectors. Details of the experiment and operation are presented.

  12. Nitrogen threshold experiment

    NASA Technical Reports Server (NTRS)

    Treat, C. L.

    1984-01-01

    In order to obtain data on Earth geologic processes associated with wind erosion, Mar's and Venus' atmospheres were simulated. Experiments were designed to observe the effects of pressure, gravity, and density on sand movement. An experiment designed to test the operator variance was a comparative test between nitrogen and carbon dioxide. Pressure and therefore density was increased until threshold was noted. Threshold was determined at precisely the same densities of the two gases. If viscosity were a contributing factor in grain saltation the effect would be noted at low pressures. The experiment showed no such variance between carbon dioxide and nitrogen runs for low pressure (density). The largest difference in viscosity between carbon dioxide and nitrogen occurs at low pressures (densities).

  13. Holographic experiments in space

    NASA Astrophysics Data System (ADS)

    Gorevich, S.

    1982-03-01

    Experiments conducted on board the Salyut-6 station to demonstrate the suitability and efficiency of the holographic method and television equipment are discussed. The holographic method is of great value to aerospace sciences. It can gather a large amount of information within a short time onboard an orbital station. The information content per exposure is increased and a three dimensional or phased information is obtained. The performance of a series of experiments by the station crew requires continuous participation and monitoring by specialists in a narrow scientific discipline and by technicians on Earth. The activities can be enhanced when television transmitted images are three dimensional.

  14. Development Experience Clearinghouse

    NSDL National Science Digital Library

    The US Agency for International Development's Development Experience Clearinghouse has recently made its Development Experience System (DEXS) available via the web. DEXS "is a family of bibliographic databases that contains records for about 100,000 Agency technical and program documents" from 1942 to the present. The database is split into two parts, 1942-86, and 1987-present. Information can be searched on any of ten variables or browsed. Retrieval includes basic bibliographic information, and may also include media, pricing, and ordering information. Of the total number of records in this staggering database, over 96,000 are available in microfiche for on-demand reproduction.

  15. The TRIO-01 experiment

    SciTech Connect

    Clemmer, R.G.; Malecha, R.F.

    1983-09-01

    The TRIO-01 experiment is a comprehensive test of in-situ tritium recovery from a miniaturized solid breeder blanket assembly. Other solid breeder blanket performance factors such as thermal hydraulics, tritium permeation, and gas phase chemistry will be tested as well. The capsule assembly is irradiated in the A2 core position of the Oak Ridge Research Reactor (ORR). Tritium release and recovery is tested by passing a He sweep gas through the solid breeder capsule measuring and collecting the tritium in the sweep stream. The TRIO-01 experiment has extensive on-line monitoring including sweep gas analysis, temperatures, neutron flux, and tritium permeation.

  16. The trio experiment

    NASA Astrophysics Data System (ADS)

    Clemmer, R. G.; Finn, P. A.; Misra, B.; Billone, M. C.; Fischer, A. K.; Tam, S. W.; Johnson, C. E.; Scandora, A. E.

    1985-08-01

    The TRIO experiment involves the irradiation of ?-LiAlO 2 under well defined conditions of temperature, neutron flux, sweep gas flow, and solid configuration. Tritium in its various chemical forms is moved by a sweep gas to an analytical train that measures and identifies the composition of the effluent. The predominant form of tritium observed in the sweep gas was the noncondensable, or HT form. At the completion of the experiment less than 0.1 wppm tritium was found in the solid.

  17. [Univerity students' exchange experience].

    PubMed

    De Caro, Walter; Maddalena, Claudio; Badolamenti, Sondra

    2004-01-01

    We report the experience of three University "La Sapienza" of Rome students (two of the Advanced Nursing master science course and one of the 3rd year of Nursing Degree) that participated to the FIPSE programme between European and Transatlantic Universities. The leader of the programme in our Country is Prof J. Sansoni. Web courses have been offered and students participated in a short period exchange at the Capital University with prof Kerr. The experience has been very positive and exciting. We really hope that this programme could be an example to other Italians Colleagues to have a look outside our Country. PMID:15134593

  18. The Rock Cycle Experiments

    NSDL National Science Digital Library

    King, Chris.

    Maintained by the BBC Education Web site, The Rock Cycle Experiments page contains ten activities related to the rock cycle, beginning with weathering and ending with the uplift of rocks. Each activity pops up after clicking the link within the very well done interactive diagram of the rock cycle. The activities are simple but effective; for example, the transportation lesson has students run water through sand to see its effects. The hands-on experience of the activities helps reinforce the learning and of course makes it fun.

  19. The Double Chooz Experiment

    E-print Network

    Daniel M. Kaplan

    2006-08-15

    There is broad consensus in the worldwide physics community as to the need for a new reactor-neutrino experiment to measure or limit the neutrino mixing angle $\\theta_{13}$. The Double Chooz Experiment, planned for operation in the years 2008-2011, will search for values of $\\sin^2{2\\theta_{13}}$ down to $\\approx$0.03. This will be the first new information on $\\theta_{13}$ in over a decade and will cover most of the remaining parameter space. A quick and relatively inexpensive project is made possible by the existing neutrino laboratory at the Chooz site.

  20. The Double Chooz Experiment

    SciTech Connect

    Kaplan, Daniel M. [Illinois Institute of Technology, 3101 South Dearborn Street, Chicago, Illinois (United States)

    2006-11-17

    There is broad consensus in the worldwide physics community as to the need for a new reactor-neutrino experiment to measure or limit the neutrino mixing angle {theta}13. The Double Chooz Experiment, planned for operation in the years 2008-2011, will search for values of sin22{theta}13 down to {approx_equal}0.03. This will be the first new information on {theta}13 in over a decade and will cover most of the remaining parameter space. A quick and relatively inexpensive project is made possible by the existing neutrino laboratory at the Chooz site.

  1. Microgravity ignition experiment

    NASA Technical Reports Server (NTRS)

    Motevalli, Vahid; Elliott, William; Garrant, Keith

    1992-01-01

    The purpose of this project is to develop a flight ready apparatus of the microgravity ignition experiment for the GASCan 2 program. This involved redesigning, testing, and making final modifications to the existing apparatus. The microgravity ignition experiment is intended to test the effect of microgravity on the time to ignition of a sample of alpha-cellulose paper. An infrared heat lamp is used to heat the paper sample within a sealed canister. The interior of the canister was redesigned to increase stability and minimize conductive heat transfer to the sample. This design was fabricated and tested and a heat transfer model of the paper sample was developed.

  2. Physics Outreach Grant Experiences

    NASA Astrophysics Data System (ADS)

    Doss, Heide

    2014-03-01

    Descriptions of two different Physics Outreach grant projects will be presented. I will discuss my experiences trying to engage and teach the public in my locality some physics through birthday parties for the laser in 2010. I will also discuss my experiences trying to reach the general public through greeting cards and bookmarks with physics on the back in 2012-2013. These efforts spilled over to a larger audience, which led to a larger impact. I will describe what worked, what didn't, and the value of these efforts. I am pleased to acknowledge the support of my funder APS Outreach.

  3. Chondrule Crystallization Experiments

    NASA Technical Reports Server (NTRS)

    Hweins, R. H.; Connolly, H. C., Jr.; Lofgren, G. E.; Libourel, G.

    2004-01-01

    Given the great diversity of chondrules, laboratory experiments are invaluable in yielding information on chondrule formation process(es) and for deciphering their initial conditions of formation together with their thermal history. In addition, they provide some critical parameters for astrophysical models of the solar system and of nebular disk evolution in particular (partial pressures, temperature, time, opacity, etc). Most of the experiments simulating chondrules have assumed formation from an aggregate of solid grains, with total pressure of no importance and with virtually no gain or loss of elements from or to the ambient environment. They used pressed pellets attached to wires and suffered from some losses of alkalis and Fe.

  4. DHS Research Experience Summary

    Microsoft Academic Search

    Venkatachalam

    2008-01-01

    I learned a great deal during my summer internship at Lawrence Livermore National Laboratory (LLNL). I plan to continue a career in research, and I feel that my experience at LLNL has been formative. I was exposed to a new area of research, as part of the Single Particle Aerosol Mass Spectrometry (SPAMS) group, and I had the opportunity to

  5. TIMED Solar EUV experiment

    Microsoft Academic Search

    Thomas N. Woods; Scott Bailey; Frank Eparvier; George Lawrence; Judith Lean; Bill McClintock; Raymond Roble; Gary J. Rottman; Stanley C. Solomon; W. Kent Tobiska

    2000-01-01

    The Solar EUV Experiment (SEE) selected for the NASA Thermosphere, Ionosphere, and Mesosphere Energetics and Dynamics (TIMED) mission will measure the solar vacuum ultraviolet (VUV) spectral irradiance from 0.1 to 200 nm. To cover this wide spectral range two different types of instruments are used: a grating spectrograph for spectra above 25 nm and a set of silicon soft x-ray

  6. A Degrading Experience

    NSDL National Science Digital Library

    Seba Sheavly

    2014-05-28

    In this activity, learners perform an experiment to learn about how different types of marine debris degrade and how weather and sunlight affect the rate of degradation. Learners discover that debris made from natural materials, while biodegradable, can still be considered pollutants and can still harm the marine environment.

  7. Energetic particle experiment ERNE

    Microsoft Academic Search

    J. Torsti; E. Valtonen; M. Lumme; P. Peltonen; T. Eronen; M. Louhola; E. Riihonen; G. Schultz; M. Teittinen; K. Ahola; C. Holmlund; V. Kelhä; K. Leppälä; P. Ruuska; E. Strömmer

    1995-01-01

    The Energetic and Relativistic Nuclei and Electron (ERNE) experiment will investigate the solar atmosphere and the heliosphere by detecting particles produced in various kinds of energy release processes. ERNE is at the upper end in energy among the SOHO particle instruments. The instrument will measure the energy spectra of elements in the range Z=1–30. The energy coverage varies dependent on

  8. Word Recognition Experiment

    NSDL National Science Digital Library

    This is the entry page for participating in the Word Recognition Experiment. This study involves a series of word recognition trials in which participants are flashed a word either in the left or in the right hemifield and then identify the presented word. Performance is measured as the minimum presentation display time required for an individual to correctly identify the word.

  9. Be A Juror Experiment

    NSDL National Science Digital Library

    This is the entry page to participate in the be a juror experiment. Participants are in one of three treatment conditions (a) no eyewitness, (b) unrefuted eyewitness, and (c) discredited eyewitness. Participants in this study rate their belief about the defendant's guilt. The rating scale ranges from a 1 (definitely not guilty) to a 7 (definitely guilty).

  10. Implicit Association Experiment

    NSDL National Science Digital Library

    This is the entry page for participation in the Implicit Association Experiment. Greenwald, McGhee and Schwartz (1998) pioneered the use of implicit association tests. Implicit association tests (IATs) measure the relative ease with which people are able to make associations between certain groups of people (e.g., older adults) and the concepts of "good" and "bad."

  11. Designing the Customer Experience

    Microsoft Academic Search

    Caroline Cole-Colander

    2003-01-01

    As the role of the professional changes, the importance of ‘the client’ and ‘the user’ is increasing. Two initiatives in the UK have sought to improve design quality by bridging the gap between the client and the user on the one hand, and the client and the designer on the other. These initiatives, ‘Designing the Customer Experience’ and ‘Design Quality

  12. Celebrating Life's Experiences.

    ERIC Educational Resources Information Center

    Smith, David B.

    1997-01-01

    For six weeks, 25 Connecticut seventh graders interviewed senior citizens from a nearby assisted-independent-living facility. By celebrating their senior partners' life experiences, students formulated a better understanding of major events in 20th century American history. During the fifth and sixth weeks, students shared something from their own…

  13. Agricultural Experiment Station

    E-print Network

    Lawrence, Rick L.

    of legume and weed aboveground biomass was collected and samples from select plots were analyzed for plant seeding rate, the resulting crop density, and termination timing on weed biomass and N fixation by LGM. METHODS Field plot experiments were conducted at Conrad and Power, MT in 2010. Two LGM crops, pea (Pisum

  14. The MAJORANA Experiment

    SciTech Connect

    Guiseppe, V.E. [Univ S Dakota; Keller, C. [Univ S Dakota; Mei, D-M [Univ S Dakota; Perevozchikov, O. [Univ S Dakota; Perumpilly, G. [Univ S Dakota; Thomas, K. [Univ S Dakota; Xiang, W. [Univ S Dakota; Zhang, C. [Univ S Dakota; Aalseth, C.E. [Pacific NW Natl Lab Richland, WA; Aguayo, E. [Pacific NW Natl Lab Richland, WA; Ely, J. [Pacific NW Natl Lab Richland, WA; Fast, J.E. [Pacific NW Natl Lab Richland, WA; Hoppe, E.W. [Pacific NW Natl Lab Richland, WA; Hossbach, T.W. [Pacific NW Natl Lab Richland, WA; Keillor, M. [Pacific NW Natl Lab Richland, WA; Kephart, J.D. [Pacific NW Natl Lab Richland, WA; Kouzes, R. [Pacific NW Natl Lab Richland, WA; Miley, H.S. [Pacific NW Natl Lab Richland, WA; Mizouni, L. [Pacific NW Natl Lab Richland, WA; Myers, A.W. [Pacific NW Natl Lab Richland, WA; Reid, D. [Pacific NW Natl Lab Richland, WA; Amman, M. [Lawrence Berkeley National Laboratory (LBNL); Bergevin, M. [Lawrence Berkeley National Laboratory (LBNL); Chan, Y-D [Lawrence Berkeley National Laboratory (LBNL); Detwiler, J.A. [Lawrence Berkeley National Laboratory (LBNL); Loach, J.C. [Lawrence Berkeley National Laboratory (LBNL); Luke, P.N. [Lawrence Berkeley National Laboratory (LBNL); Martin, R.D. [Lawrence Berkeley National Laboratory (LBNL); Poon, A.W.P. [Lawrence Berkeley National Laboratory (LBNL); Prior, G. [Lawrence Berkeley National Laboratory (LBNL); Vetter, K. [Lawrence Berkeley National Laboratory (LBNL); Yaver, H. [Lawrence Berkeley National Laboratory (LBNL); Avignone, F.T. III [University of South Carolina; Creswick, R. [University of South Carolina; Farach, H. [University of South Carolina; Mizouni, L. [University of South Carolina; Avignone, Frank Titus [ORNL; Bertrand Jr, Fred E [ORNL; Capps, Gregory L [ORNL; Cooper, Reynold J [ORNL; Radford, David C [ORNL; Varner Jr, Robert L [ORNL; Wilkerson, John F [University of North Carolina, Chapel Hill; Yu, Chang-Hong [ORNL; Back, H.O. [University of North Carolina; Leviner, L. [North Carolina State University; Young, A.R. [North Carolina State University; Back (et al.), H.O. [Triangle Universities Nuclear Laboratory, Durham, NC; Bai, X. [South Dakota School of Mines and Technology; Hong, H. [South Dakota School of Mines and Technology; Howard, S. [South Dakota School of Mines and Technology; Medlin, D. [South Dakota School of Mines and Technology; Sobolev, V. [South Dakota School of Mines and Technology; Barabash, A.S. [Inst Theort & Expt Phys, Moscow, Russia; Konovalov, S.I. [Inst Theort & Expt Phys, Moscow, Russia; Vanyushin, I. [Inst Theort & Expt Phys, Moscow, Russia; Yumatov, V. [Inst Theort & Expt Phys, Moscow, Russia; Barbeau, P.S. [University of Chicago; Collar, J.I. [University of Chicago; Fields, N. [University of Chicago; Boswell (et al.), M. [Los Alamos National Laboratory (LANL); Brudanin, V. [Joint Institute for Nuclear Research, Dubna, Russia; Egorov, V. [Joint Institute for Nuclear Research, Dubna, Russia; Gusey, K. [Joint Institute for Nuclear Research, Dubna, Russia; Kochetov, O. [Joint Institute for Nuclear Research, Dubna, Russia; Shirchenko, M. [Joint Institute for Nuclear Research, Dubna, Russia; Timkin, V. [Joint Institute for Nuclear Research, Dubna, Russia; Yakushev, E. [Joint Institute for Nuclear Research, Dubna, Russia; Bugg, W. [University of Tennessee, Knoxville (UTK); Efremenko, M. [University of Tennessee, Knoxville (UTK); Burritt (et al.), T.H. [University of Washington, Ctr Expt Nucle Phys & Astrophys; Burritt (et al.), T.H. [University of Washington, Dept Phys, Seattle, WA; Busch, M. [Duke University; Esterline, J. [Duke University; Swift, G. [Duke University; Tornow, W. [Duke University/TUNL; Ejiri, H. [Osaka University; Hazama, R. [Osaka University; Nomachi, M. [Osaka University; Shima, T. [Osaka University; Finnerty (et al.), P. [University of North Carolina; et al.

    2011-01-01

    The Majorana Collaboration is assembling an array of HPGe detectors to search for neutrinoless double-beta decay in {sup 76}Ge. Initially, Majorana aims to construct a prototype module to demonstrate the potential of a future 1-tonne experiment. The design and potential reach of this prototype Demonstrator module are presented.

  15. Notes on Experiments.

    ERIC Educational Resources Information Center

    Bligh, P. H.; And Others

    1988-01-01

    Introduces three physics experiments for high school and college classes. Topics include measuring the ratio of heat capacities using a microcomputer and a glass syringe, producing large electric sparks using a variation of a Leyden bucket, and observing transmission line behavior using television signals. Includes descriptions of materials and…

  16. SPIRE - Spectral Infrared Experiment

    Microsoft Academic Search

    R. M. Nadile; N. B. Wheeler; A. T. Stair Jr.; D. G. Frodsham; C. L. Wyatt

    1977-01-01

    A Spectral Infrared Experiment (SPIRE) rocket payload designed to make selective measurements of the sunlit earth limb is described. Two cryogenically cooled CVF spectrometers and a dual channel photometer will be used to spatially and spectrally map the horizon from 5000A to 15.5 microns. All three sensors have been telescoped with low scatter optics which are capable of resolving an

  17. Experiences in Systemic Change

    ERIC Educational Resources Information Center

    Thompson, Scott; Clem, Joe; Battino, Wendy; Richter, Kurt; Reigeluth, Charles; Doll, Marcelle; Moore, Julie; Hoo, Janet; Malopinsky, Larissa V.

    2006-01-01

    This section describes the systemic change experiences in Norfolk Public Schools, Chugach School District, Indianapolis Metropolitan School District of Decatur Township, Ditmas Educational Complex, Georgia Systemic Teacher Education Program, Sun Microsystems, and Azerbaijan. It provides a description of the change process and discusses the…

  18. Experiments on Photoconductivity

    ERIC Educational Resources Information Center

    Kraftmakher, Yaakov

    2012-01-01

    Computer-assisted experiments with CdS and CdSe photoresistors are described. The most important characteristics of the photoresistors are determined: (i) the spectral response, (ii) the photocurrent versus incident radiant power, (iii) the rise and decay time constants and (iv) the frequency response to modulated light. The photoconductivity gain…

  19. Experimenting with Guitar Strings

    NASA Astrophysics Data System (ADS)

    LoPresto, Michael C.

    2006-11-01

    What follows is a description of a simple experiment developed in a nonmathematical general education science course on sound and light for fine arts students in which a guitar is used with data collection hardware and software to verify the properties of standing waves on a string.

  20. Alpha Antihydrogen Experiment

    NASA Astrophysics Data System (ADS)

    Fujiwara, M. C.; Andresen, G. B.; Ashkezari, M. D.; Baquero-Ruiz, M.; Bertsche, W.; Bray, C. C.; Butler, E.; Cesar, C. L.; Chapman, S.; Charlton, M.; Cesar, C. L.; Fajans, J.; Friesen, T.; Gill, D. R.; Hangst, J. S.; Hardy, W. N.; Hayano, R. S.; Hayden, M. E.; Humphries, A. J.; Hydomako, R.; Jonsell, S.; Kurchaninov, L.; Lambo, R.; Madsen, N.; Menary, S.; Nolan, P.; Olchanski, K.; Olin, A.; Povilus, A.; Pusa, P.; Robicheaux, F.; Sarid, E.; Silveira, D. M.; So, C.; Storey, J. W.; Thompson, R. I.; van der Werf, D. P.; Wilding, D.; Wurtele, J. S.; Yamazaki, Y.

    2011-12-01

    ALPHA is an experiment at CERN, whose ultimate goal is to perform a precise test of CPT symmetry with trapped antihydrogen atoms. After reviewing the motivations, we discuss our recent progress toward the initial goal of stable trapping of antihydrogen, with some emphasis on particle detection techniques.

  1. An analemma experiment

    Microsoft Academic Search

    Dan M. Davis

    2000-01-01

    I describe here a very simple experiment that allows a science class to measure the latitude of their school, determine the inclination of the Earth's axis to the ecliptic, and demonstrate the noncircularity of our orbit around the Sun. The only tools needed are: something tall and pointed (a flagpole will do), paint and a paint brush, a tape measure,

  2. STUDENT EXPERIENCE Reid Polmanteer

    E-print Network

    Mottram, Nigel

    company of geological consultants for the oil and gas industry. I maintained geologic logs during drillingSTUDENT EXPERIENCE Reid Polmanteer MSc Hydrogeology with Distinction (2012-2013) Q. What was your hydrogeology. Afterward I worked as an environmental geologist for a year at a consulting firm. The work

  3. The Majorana Experiment

    SciTech Connect

    Aalseth, Craig E.; Aguayo Navarrete, Estanislao; Amman, M.; Avignone, F. T.; Back, Henning O.; Bai, Xinhua; Barabash, Alexander S.; Barbeau, P. S.; Bergevin, M.; Bertrand, F.; Boswell, M.; Brudanin, V.; Bugg, William; Burritt, Tom H.; Busch, Matthew; Capps, Greg L.; Chan, Yuen-Dat; Collar, J. I.; Cooper, R. J.; Creswick, R.; Detwiler, Jason A.; Diaz, J.; Doe, Peter J.; Efremenko, Yuri; Egorov, Viatcheslav; Ejiri, H.; Elliott, S. R.; Ely, James H.; Esterline, James H.; Farach, H. A.; Fast, James E.; Fields, N.; Finnerty, P.; Fraenkle, Florian; Gehman, Victor M.; Giovanetti, G. K.; Green, M.; Guiseppe, Vincente; Gusey, K.; Hallin, A. L.; Harper, Gregory; Hazama, R.; Henning, Reyco; Hime, Andrew; Hong, H.; Hoppe, Eric W.; Hossbach, Todd W.; Howard, Stanley; Howe, M. A.; Johnson, R. A.; Keeter, K.; Keillor, Martin E.; Keller, C.; Kephart, Jeremy D.; Kidd, M. F.; Knecht, A.; Kochetov, Oleg; Konovalov, S.; Kouzes, Richard T.; LaRoque, B. H.; Leviner, L.; Loach, J. C.; Luke, P.; MacMullin, S.; Marino, Michael G.; Martin, R. D.; Medlin, D.; Mei, Dong-Ming; Miley, Harry S.; Miller, M. L.; Mizouni, Leila; Myers, Allan W.; Nomachi, Masaharu; Orrell, John L.; Peterson, David; Phillips, D.; Poon, Alan; Perevozchikov, O.; Perumpilly, Gopakumar; Prior, Gersende; Radford, D. C.; Reid, Douglas J.; Rielage, Keith; Robertson, R. G. H.; Rodriguez, Larry; Ronquest, M. C.; Salazar, Harold; Schubert, Alexis G.; Shima, T.; Shirchenko, M.; Sobolev, V.; Steele, David; Strain, J.; Swift, Gary; Thomas, K.; Timkin, V.; Tornow, W.; Van Wechel, T. D.; Vanyushin, I.; Varner, R. L.; Vetter, Kai; Vorren, Kris R.; Wilkerson, J. F.; Wolfe, B. A.; Xiang, W.; Yakushev, E.; Yaver, Harold; Young, A.; Yu, Chang-Hong; Yumatov, V.; Zhang, C.

    2011-08-01

    The Majorana Collaboration is assembling an array of HPGe detectors to search for neutrinoless double-beta decay in 76Ge. Initially, Majorana aims to construct a prototype module to demonstrate the potential of a future 1-tonne experiment. The design and potential reach of this prototype Demonstrator module are presented.

  4. Music: A Shared Experience.

    ERIC Educational Resources Information Center

    Dunn, Rosemary

    1992-01-01

    This paper describes how sixth form girls in England provided music experiences to young children (ages 3-9) with severe learning difficulties. The weekly sessions involve individual sessions and use of various instruments. The relationship of the music therapy program to the National Curriculum is noted. (DB)

  5. Reconstructing Playschool Experiences

    ERIC Educational Resources Information Center

    Einarsdottir, Johanna

    2011-01-01

    The current study was conducted with groups of first grade children (aged six years) in two primary schools in Reykjavik in an endeavour to ascertain how they recalled and reconstructed their playschool experiences. The children's playschool teachers were co-researchers participating in the data generation; they were, at the same time participants…

  6. The Experience of Menarche.

    ERIC Educational Resources Information Center

    Ruble, Diane N.; Brooks-Gunn, Jeanne

    1982-01-01

    Examines reactions to menarche and the subsequent effects of this experience as a function of preparation for and timing of menarche. A questionnaire including measures of responses about first menstruation, current symptoms, and self-image was completed by 639 girls in fifth through twelfth grades. (Author/MP)

  7. Carbon monoxide pollution experiment

    NASA Technical Reports Server (NTRS)

    Bortner, M. H.; Dick, R.; Goldstein, H. W.; Grenda, R. N.

    1975-01-01

    The experiment is designed to obtain data for the investigation of mechanisms by which CO is removed from the earth's atmosphere. The approach uses an orbiting platform to remotely map global CO concentrations and determine vertical CO profiles using a correlation interferometer measurement technique. The instrument is capable of measuring CO over the range of expected atmospheric burdens and of measuring trace atmospheric constituents.

  8. Experimenting with Electric Trains

    ERIC Educational Resources Information Center

    Wick, D. P.; Ramsdell, M. W.

    2007-01-01

    A simple experiment can be performed to characterize the relationship between applied voltage and velocity (steady state and transient) for an electric toy train. The results can be used by teams of students to solve a series of challenges in which they attempt to predict the performance of a particular train. Some sample challenges might include…

  9. The TRIO01 experiment

    Microsoft Academic Search

    R. G. Clemmer; R. F. Malecha

    1983-01-01

    The TRIO-01 experiment is a comprehensive test of in-situ tritium recovery from a miniaturized solid breeder blanket assembly. Other solid breeder blanket performance factors such as thermal hydraulics, tritium permeation, and gas phase chemistry will be tested as well. The capsule assembly is irradiated in the A2 core position of the Oak Ridge Research Reactor (ORR). Tritium release and recovery

  10. SAMBA Project Experiences

    NASA Astrophysics Data System (ADS)

    Fuhrhop, Christian; Vaidya, Raju; Mayora, Oscar; Furtado, Elizabeth

    The purpose of the SAMBA project, running from January 2007 to February 2009, was to create a framework for allowing local communities and citizens (including low income population) to access community-oriented content and services by means of iDTV channels, specifically MHP over DVB-T. This paper summarises the project and the experiences gained from it.

  11. Parent Hearing Aid Experiences

    ERIC Educational Resources Information Center

    Munoz, Karen; Roberts, Mallory; Mullings, Day; Harward, Richard

    2012-01-01

    This study addresses parent experiences in obtaining and managing hearing aids for their young child. The purpose was to identify challenges parents encounter to determine what state agencies can do to improve parent access to amplification. Data were collected July through September of 2010; 40 parents of children ages birth to 3 years old…

  12. Learning: A Multifarious Experience.

    ERIC Educational Resources Information Center

    Furuness, Linda B.; Cohen, Michael R.

    Science education has often struggled to determine effective teaching methodologies and learning strategies. One promising field of research has been that of alternative frameworks. The research described in this paper describes how immersion in an unfamiliar environment and culture affected teacher learning, some of the significant experiences

  13. Experiments in ESP.

    ERIC Educational Resources Information Center

    Guerin, Stephen M.; Guerin, Clark L.

    1979-01-01

    Discusses a phenomenon called Extrasensory Perception (ESP) whereby information is gained directly by the mind without the use of the ordinary senses. Experiments in ESP and the basic equipment and methods are presented. Statistical evaluation of ESP experimental results are also included. (HM)

  14. DSWA calorimeter bomb experiments

    SciTech Connect

    Cunningham, B

    1998-10-01

    Two experiments were performed in which 25 grams of TNT were detonated inside an expended detonation calorimeter bomb. The bomb had a contained volume of approximately 5.28 liters. In the first experiment, the bomb was charged with 3 atmospheres of nitrogen. In the second, it was charged with 2.58 atmospheres (23.1 psi gage) of oxygen. In each experiment pressure was monitored over a period of approximately 1200 microseconds after the pulse to the CDU. Monitoring was performed via two 10,000 psi 102AO3 PCB high frequency pressure transducers mounted symmetrically in the lid of the calorimeter bomb. Conditioners used were PCB 482As. The signals from the transducers were recorded in digital format on a multi channel Tektronix scope. The sampling frequency was 10 Mhz (10 samples per microsecond). After a period of cooling following detonation, gas samples were taken and were subsequently submitted for analysis using gas mass spectrometry. Due to a late request for post shot measurement, it was only possible to make a rough estimate of the weight of debris (carbon) remaining in the calorimeter bomb following the second experiment.

  15. Science and Human Experience

    NASA Astrophysics Data System (ADS)

    Cooper, Leon N.

    2015-01-01

    Part I. Science and Society: 1. Science and human experience; 2. Does science undermine our values?; 3. Can science serve mankind?; 4. Modern science and contemporary discomfort: metaphor and reality; 5. Faith and science; 6. Art and science; 7. Fraud in science; 8. Why study science? The keys to the cathedral; 9. Is evolution a theory? A modest proposal; 10. The silence of the second; 11. Introduction to Copenhagen; 12. The unpaid debt; Part II. Thought and Consciousness: 13. Source and limits of human intellect; 14. Neural networks; 15. Thought and mental experience: the Turing test; 16. Mind as machine: will we rubbish human experience?; 17. Memory and memories: a physicist's approach to the brain; 18. On the problem of consciousness; Part III. On the Nature and Limits of Science: 19. What is a good theory?; 20. Shall we deconstruct science?; 21. Visible and invisible in physical theory; 22. Experience and order; 23. The language of physics; 24. The structure of space; 25. Superconductivity and other insoluble problems; 26. From gravity to light and consciousness: does science have limits?

  16. A Monopoly Classroom Experiment.

    ERIC Educational Resources Information Center

    Oxoby, Robert J.

    2001-01-01

    Uses a simple classroom experiment to develop the economic model of monopoly. Introduces students to the nature of the monopoly problem and motivates them to think of the associated effects. Highlights the role of information and fairness ideals in determining economic outcomes. (RLH)

  17. Experiments in free fall

    NASA Astrophysics Data System (ADS)

    Art, Albert

    2006-09-01

    A model lift containing a figure of Albert Einstein is released from the side of a tall building and its free fall is arrested by elastic ropes. This arrangement allows four simple experiments to be conducted in the lift to demonstrate the effects of free fall and show how they can lead to the concept of the equivalence of inertial and gravitational masses.

  18. A Harmonic Motion Experiment

    ERIC Educational Resources Information Center

    Gluck, P.; Krakower, Zeev

    2010-01-01

    We present a unit comprising theory, simulation and experiment for a body oscillating on a vertical spring, in which the simultaneous use of a force probe and an ultrasonic range finder enables one to explore quantitatively and understand many aspects of simple and damped harmonic motions. (Contains 14 figures.)

  19. Flight control experiences

    NASA Technical Reports Server (NTRS)

    Musgrave, F. S.

    1977-01-01

    A multidisciplinary medical-management team at mission control provided Skylab crew support by monitoring health, retrieving and compiling experimental data, assisting in the development of flight plans, and by contributing to in-flight procedures and checklists. Real time computers assisted the flight crews in performing medical and other experiments.

  20. Holistic Graduate Student Experience

    E-print Network

    Sabatini, David M.

    students--to resources such as the ODGE website, other online resources, videos, and the student life and learning webpage. #12;38 HolisticGraduateStudentExperience » Provide Resource Training. In conjunction, access to resources, work-life balance, and community are increasingly important to the academic

  1. Chlorine solar neutrino experiment

    SciTech Connect

    Rowley, J.K.; Cleveland, B.T.; Davis R. Jr.

    1985-01-25

    The chlorine solar neutrino experiment in the Homestake Gold Mine is described and the results obtained with the chlorine detector over the last fourteen years are summarized and discussed. Background processes producing /sup 37/Ar and the question of the constancy of the production rate of /sup 37/Ar are given special emphasis.

  2. Chlorine solar neutrino experiment

    SciTech Connect

    Rowley, J.K.; Cleveland, B.T.; Davis, R. Jr.

    1984-01-01

    The chlorine solar neutrino experiment in the Homestake Gold Mine is described and the results obtained with the chlorine detector over the last fourteen years are summarized and discussed. Background processes producing /sup 37/Ar and the question of the constancy of the production rate of /sup 37/Ar are given special emphasis.

  3. Finite Order Statistic Experiment

    NSDL National Science Digital Library

    Kyle Siegrist

    This resource consists of a Java applet and expository text. The applet is a simulation of the experiment of selecting n objects at random from the first m positive integers. The random variables of interest are the order statistics. The applet illustrates the distributions of the order statistics.

  4. The Double Chooz Experiment

    Microsoft Academic Search

    Andi S. Cucoanes

    2008-01-01

    One of the main interests for nowadays neutrino physics is the knowledge of the mixing angle Theta13. The present limit is given by the CHOOZ experiment. The Double Chooz Collaboration aims for a reactor antineutrino flux measurement with two identical detectors placed at ~250 m and respectively ~1 km from the reactor cores as the search for a non-vanishing Theta13

  5. Cyclic Voltammetry Experiment.

    ERIC Educational Resources Information Center

    Van Benschoten, James J.; And Others

    1983-01-01

    Describes a three-part experiment designed to introduce cyclic voltammetry to graduate/undergraduate students. Part 1 demonstrates formal reduction potential, redox electron transfer, diffusion coefficient, and electrochemical reversibility. Part 2 investigates electrochemical behavior of acetaminophen. Part 3 examines such experimental variables…

  6. Gender Perception Experiment

    NSDL National Science Digital Library

    This is the entry page for participation in the gender perception experiment. Participants view photographs of faces and only the mouth and chin regions are visible. Participants are asked to identify the gender of each stimulus and to indicate their confidence in their judgment.

  7. Electrophoresis experiments in microgravity

    NASA Technical Reports Server (NTRS)

    Snyder, Robert S.; Rhodes, Percy H.

    1991-01-01

    The use of the microgravity environment to separate and purify biological cells and proteins has been a major activity since the beginning of the NASA Microgravity Science and Applications program. Purified populations of cells are needed for research, transplantation and analysis of specific cell constituents. Protein purification is a necessary step in research areas such as genetic engineering where the new protein has to be separated from the variety of other proteins synthesized from the microorganism. Sufficient data are available from the results of past electrophoresis experiments in space to show that these experiments were designed with incomplete knowledge of the fluid dynamics of the process including electrohydrodynamics. However, electrophoresis is still an important separation tool in the laboratory and thermal convection does limit its performance. Thus, there is a justification for electrophoresis but the emphasis of future space experiments must be directed toward basic research with model experiments to understand the microgravity environment and fluid analysis to test the basic principles of the process.

  8. Microgravity ignition experiment

    NASA Technical Reports Server (NTRS)

    Motevalli, Vahid; Elliott, William; Garrant, Keith; Marcotte, Ryan

    1992-01-01

    The purpose of this project is to develop a flight-ready apparatus of the microgravity ignition experiment for the GASCAN 2 program. The microgravity ignition experiment is designed to study how a microgravity environment affects the time to ignition of a sample of alpha-cellulose paper. A microgravity environment will result in a decrease in the heat transferred from the sample due to a lack of convection currents, which would decrease time to ignition. A lack of convection current would also cause the oxygen supply at the sample not to be renewed, which could delay or even prevent ignition. When this experiment is conducted aboard GASCAN 2, the dominant result of the lack of ignition will be determined. The experiment consists of four canisters containing four thermocouples and a sensor to detect ignition of the paper sample. This year the interior of the canister was redesigned and a mathematical model of the heat transfer around the sample was developed. This heat transfer model predicts an ignition time of approximately 5.5 seconds if the decrease of heat loss from the sample is the dominant factor of the lack of convection currents.

  9. Global Health Field Experience

    E-print Network

    Global Health Field Experience Guide Yale College Center for International and Professional in global health and looking for guidance on where to begin. It provides valuable information about choosing of global health field work. With the suggestions and tools listed here, we hope that students new to global

  10. ATA beam director experiment

    SciTech Connect

    Lee, E.P.; Younger, F.C.; Cruz, G.E.; Nolting, E.

    1986-06-23

    This report describes beam director elements for an experiment at the Advanced Test Accelerator. The elements described include a vernier magnet for beam aiming, an achromat magnet, and an isolation system for the beam interface. These components are built at small scale for concept testing. (JDH)

  11. Collaborative engagement experiment

    Microsoft Academic Search

    Katherine Mullens; Bradley Troyer; Robert Wade; Brian Skibba; Michael Dunn

    2006-01-01

    Unmanned ground and air systems operating in collaboration have the potential to provide future Joint Forces a significant capability for operations in complex terrain. Collaborative Engagement Experiment (CEE) is a consolidation of separate Air Force, Army and Navy collaborative efforts within the Joint Robotics Program (JRP) to provide a picture of the future of unmanned warfare. The Air Force Research

  12. The OLYMPUS experiment

    NASA Astrophysics Data System (ADS)

    Milner, R.; Hasell, D. K.; Kohl, M.; Schneekloth, U.; Akopov, N.; Alarcon, R.; Andreev, V. A.; Ates, O.; Avetisyan, A.; Bayadilov, D.; Beck, R.; Belostotski, S.; Bernauer, J. C.; Bessuille, J.; Brinker, F.; Buck, B.; Calarco, J. R.; Carassiti, V.; Cisbani, E.; Ciullo, G.; Contalbrigo, M.; D'Ascenzo, N.; De Leo, R.; Diefenbach, J.; Donnelly, T. W.; Dow, K.; Elbakian, G.; Eversheim, D.; Frullani, S.; Funke, Ch.; Gavrilov, G.; Gläser, B.; Görrissen, N.; Hauschildt, J.; Henderson, B. S.; Hoffmeister, Ph.; Holler, Y.; Ice, L. D.; Izotov, A.; Kaiser, R.; Karyan, G.; Kelsey, J.; Khaneft, D.; Klassen, P.; Kiselev, A.; Krivshich, A.; Lehmann, I.; Lenisa, P.; Lenz, D.; Lumsden, S.; Ma, Y.; Maas, F.; Marukyan, H.; Miklukho, O.; Movsisyan, A.; Murray, M.; Naryshkin, Y.; O'Connor, C.; Perez Benito, R.; Perrino, R.; Redwine, R. P.; Rodríguez Piñeiro, D.; Rosner, G.; Russell, R. L.; Schmidt, A.; Seitz, B.; Statera, M.; Thiel, A.; Vardanyan, H.; Veretennikov, D.; Vidal, C.; Winnebeck, A.; Yeganov, V.

    2014-03-01

    The OLYMPUS experiment was designed to measure the ratio between the positron-proton and electron-proton elastic scattering cross-sections, with the goal of determining the contribution of two-photon exchange to the elastic cross-section. Two-photon exchange might resolve the discrepancy between measurements of the proton form factor ratio, ?pGEp/GMp, made using polarization techniques and those made in unpolarized experiments. OLYMPUS operated on the DORIS storage ring at DESY, alternating between 2.01 GeV electron and positron beams incident on an internal hydrogen gas target. The experiment used a toroidal magnetic spectrometer instrumented with drift chambers and time-of-flight detectors to measure rates for elastic scattering over the polar angular range of approximately 25°-75°. Symmetric Møller/Bhabha calorimeters at 1.29° and telescopes of GEM and MWPC detectors at 12° served as luminosity monitors. A total luminosity of approximately 4.5 fb-1 was collected over two running periods in 2012. This paper provides details on the accelerator, target, detectors, and operation of the experiment.

  13. Ganges valley aerosol experiment.

    SciTech Connect

    Kotamarthi, V.R.; Satheesh, S.K. (Environmental Science Division); (Indian Institute of Science, Bangalore, India)

    2011-08-01

    In June 2011, the Ganges Valley Aerosol Experiment (GVAX) began in the Ganges Valley region of India. The objective of this field campaign is to obtain measurements of clouds, precipitation, and complex aerosols to study their impact on cloud formation and monsoon activity in the region.

  14. Experiments with Aspirin.

    ERIC Educational Resources Information Center

    Borer, Londa L.; Barry, Edward

    2000-01-01

    Presents a series of experiments that can be used to demonstrate how aspirin can be synthesized and characterized, how the hydrolysis of aspirin can be used as an introduction to kinetics, and how coordination chemistry (chelation) can be introduced by preparing and characterizing the copper complexes of aspirin and salicylic acid. (Contains over…

  15. Revisiting Supervised Agricultural Experience.

    ERIC Educational Resources Information Center

    Camp, William G.; Clarke, Ariane; Fallon, Maureen

    2000-01-01

    A Delphi panel of 40 agricultural educators unanimously agreed that supervised agricultural experience should remain an integral component of the curriculum; a name change is not currently warranted. Categories recommended were agribusiness entrepreneurship, placement, production, research, directed school lab, communications, exploration, and…

  16. The Doppler Pendulum Experiment

    ERIC Educational Resources Information Center

    Lee, C. K.; Wong, H. K.

    2011-01-01

    An experiment to verify the Doppler effect of sound waves is described. An ultrasonic source is mounted at the end of a simple pendulum. As the pendulum swings, the rapid change of frequency can be recorded by a stationary receiver using a simple frequency-to-voltage converter. The experimental results are in close agreement with the Doppler…

  17. Virtual Inquiry Experiences

    ERIC Educational Resources Information Center

    Harlow, Danielle; Nilsen, Katy

    2011-01-01

    Children in classrooms and scientists in laboratories engage in similar activities: they observe, ask questions, and try to explain phenomena. Video conferencing technology can remove the wall between the classroom and the laboratory, bringing children and scientists together. Virtual experiences and field trips can provide many of the benefits of…

  18. [Environmental Education Experiences].

    ERIC Educational Resources Information Center

    Burke County Board of Education, Morganton, NC.

    Environmental/ecological experiences, appropriate for elementary grades, are presented in this compilation. Designed as individual units of study, they consider components of the natural environment and in particular the local environment of Burke County, North Carolina. Units are titled: Burke County in a Nutshell, Our Culture, A Tour of the…

  19. A Simple Adsorption Experiment

    ERIC Educational Resources Information Center

    Guirado, Gonzalo; Ayllon, Jose A.

    2011-01-01

    The study of adsorption phenomenon is one of the most relevant and traditional physical chemistry experiments performed by chemistry undergraduate students in laboratory courses. In this article, we describe an easy, inexpensive, and straightforward way to experimentally determine adsorption isotherms using pieces of filter paper as the adsorbent…

  20. Categorizing My Leadership Experiences

    ERIC Educational Resources Information Center

    Domenech, Daniel A.

    2005-01-01

    In this article, the author shares his experience as a superintendent fortunate enough to be part of the Wallace Foundation's Project LEAD. Along with 11 other superintendents, he got to trade war stories with the likes of Ron Heifetz and other distinguished faculty members from the Kennedy School of Government at Harvard. The group's first…

  1. Experiments with Kathode Rays

    Microsoft Academic Search

    William Ramsay

    1912-01-01

    DURING a research which is being carried out in conjunction with my colleague, Prof. Norman Collie, two experiments have been made the results of which are of some interest. Sir James Mackenzie Davidson was so kind as to furnish us with four deeply stained X-ray bulbs, which had been long in use, and had been rejected. These bulbs were broken

  2. INTERNATIONAL SODAR INTERCOMPARISON EXPERIMENT

    EPA Science Inventory

    The paper presents preliminary results from the International Sodar Intercomparison Experiment (ISlE) conducted at the Boulder Atmospheric Observatory in September 1988. wenty-minute mean wind speeds and directions from a variety of sodar systems compare well with measurements on...

  3. A harmonic motion experiment

    Microsoft Academic Search

    P. Gluck; Zeev Krakower

    2010-01-01

    We present a unit comprising theory, simulation and experiment for a body oscillating on a vertical spring, in which the simultaneous use of a force probe and an ultrasonic range finder enables one to explore quantitatively and understand many aspects of simple and damped harmonic motions.

  4. Thermal Control Surfaces Experiment

    NASA Technical Reports Server (NTRS)

    Wilkes, D. R.

    1999-01-01

    This report is the final experiment report for the TCSE and summarizes many years of hardware development and analyses. Also included are analyses presented in a number of TCSE papers that were prepared and given at scientific conferences including three LDEF Post-Retrieval Symposiums.

  5. Research Experience for Undergraduates

    E-print Network

    Tennessee, University of

    with Disabilities, and Underrepresented Students are encouraged to apply application deadline: March 15, 2015 applyResearch Experience for Undergraduates S t a r t D a te : J u n e 1 , 2 0 1 5 K n oxv i l l e , T N Networks (CURENT) is a National Science Foundation and Department of Energy Engineering Research Center

  6. Ice forming experiment

    NASA Technical Reports Server (NTRS)

    Vali, G.

    1982-01-01

    A low gravity experiment to assess the effect of the presence of supercooled cloud droplets on the diffusional growth rate of ice crystals is described. The theoretical work and the feasibility studies are summarized. The nucleation of ice crystals in supercooled clouds is also discussed.

  7. The Dorm Five Experiment

    ERIC Educational Resources Information Center

    Birch, Jeremy

    1975-01-01

    Describes the Dorm 5 experiment at Windham College, Putney, Vermont, designed to create a living environment to assure individual rights and intellectual values through positive reinforcement techniques following operant conditioning. Problems of vandalism and noise were solved as physical space was utilized to meet student needs for social and…

  8. Staying Warm Winter Experiments

    NSDL National Science Digital Library

    These experiments use simple materials to prove that a lot of one's body heat escapes from one's head and that wearing a hat stops some of this heat loss. In addition, students consider how sitting directly on cold ground will cause one to lose heat faster than sitting on insulating material.

  9. YOUNG'S INTERFERENCE EXPERIMENT

    E-print Network

    Visser, Taco D.

    interest was in sense perception, and he was the first to realize that the eye focuses by changing with Helmholtz, of the three-color theory of perception, believing that the eye constructs its sense of color [2]." Better known today is his two-slit experiment (see Fig. 2) in which the light em- anating from

  10. Experiment with Conical Pendulum

    ERIC Educational Resources Information Center

    Tongaonkar, S. S.; Khadse, V. R.

    2011-01-01

    Conical pendulum is similar to simple pendulum with the difference that the bob, instead of moving back and forth, swings around in a horizontal circle. Thus, in a conical pendulum the bob moves at a constant speed in a circle with the string tracing out a cone. This paper describes an experiment with conical pendulum, with determination of g from…

  11. Design Space Exploration of Parameterized Systems using Design of Experiments

    E-print Network

    Sheldon, David

    2011-01-01

    Experiments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Experiments . . . . . . . . . . . . . . . . . . . . . . . . . . . .using design of experiments (DoE) . . . . . . . . . . . . .

  12. FIELD EXPERIENCE MANUAL/GUIDE Field Experience in Health Education

    E-print Network

    Gering, Jon C.

    FIELD EXPERIENCE MANUAL/GUIDE HLTH 460 Field Experience in Health Education (6.0 hours credit: HLTH 460, Field Experience in Health Education HLTH 460, Field Experience in Health Education (6 credit to apply the responsibilities and competencies of the entry-level health educator in an off-campus health

  13. Formulating mixed models for experiments, including longitudinal experiments

    E-print Network

    Brien, Chris

    Formulating mixed models for experiments, including longitudinal experiments C. J. Brien1 and C of experiments, particularly those that require more complicated models (e.g. those that involve longitudinal-phase experiment to investigate the effect of time of refinement on Eucalyptus pulp from four different sources

  14. Transformations of emotional experience.

    PubMed

    de Cortiñas, Lia Pistiner

    2013-06-01

    In this paper the author approaches mental pain and the problems in a psychoanalytic treatment of patients with difficulties in the psychic transformation of their emotional experiences. The author is interested in the symbolic failure related to the obstruction of development of phantasies, dreams, dream-thoughts, etc. She differentiates symbolization disturbances related to hypertrophic projective identification from a detention of these primitive communications and emotional isolation. She puts forward the conjecture that one factor in the arrest of this development is the detention of projective identifications and that, when this primitive means of communication is re-established in a container-contained relationship of mutual benefit, this initiates the development of a symbolization process that can replace the pathological 'protection'. Another hypothesis she develops is that of inaccessible caesuras that, associated with the detention of projective identification, obstruct any integrative or interactive movement. This caesura and the detention of projective identifications affect mental functions needed for dealing with mental pain. The personality is left with precarious mental equipment for transforming emotional experiences. How can a psychoanalytical process stimulate the development of creative symbolization, transforming the emotional experiences and leading towards mental growth? The author approaches the clinical problem with the metaphor of the psychic birth of emotional experience. The modulation of mental pain in a container-contained relationship is a central problem for the development of the human mind. For discovering and giving a meaning to emotional experience, the infant depends on reverie, a function necessary in order to develop an evolved consciousness capable of being aware, which is different from the rudimentary consciousness that perceives but does not understand. The development of mature mental equipment is associated with the personality's attitude towards mental pain. The differentiation between psychotic, neurotic or autistic functioning depends on what defences are erected to avoid mental pain. The primary link between infant and mother is where the building of mental equipment takes place, through communicational forms that, to begin with, are not verbal. The author suggests the need for the development of an ideo-grammar (in gestures, paralinguistic forms, etc.) in primary relations, as the precursor forms that will become the matrix for the mental tools for dealing with emotional experiences in a mature way. The paper stresses the significance of the parental containing function for the development of symbolization of prenatal emotional experiences. This containment develops ideograms, transformations of sense impressions into proto-symbols, instruments that attenuate the traumatic experiences of helplessness. The author takes Bion's ideas about extending the notion of dream-work to an alpha function that goes on continually, day and night, transforming raw emotional experiences in a 'dream'. In order to acquire a meaning, facts need to be 'dreamed' in this extended sense. Meaning and truth are the nurture of the mind. Mental growth, the development of adequate tools--including reverie--for dealing with mental pain, seen from a psychoanalytic perspective including reverie, implies that the object becomes a provider of meanings. Analysis begins to aim primarily at the generation or expansion of the mental container, instead of predominantly working on unconscious contents as such. PMID:23781834

  15. PsychExperiments: Psychology Experiments on the Internet

    NSDL National Science Digital Library

    PsychExperiments is a collection of online cognitive psychology and social psychology experiments, accompanied by a cumulative data archive and download utilities for both data and experiment source code. Students collect data using one or more of the experiments and download it for analysis. The experiments include demonstrations, lab experiments for collecting data for in-class analysis, and research experiments in which participants take part and contribute data to an archive. Topics include the psychology of jurors, facial recognition, learning and memory, perception of gender, reaction time, and many others. Other resources include downloadable Excel macros for analyzing data from the experiments, and support materials for those who want to use and/or develop experiments at the site. A training manual for creating experiments in Authorware is available for purchase.

  16. Electrohydrodynamic heat pipe experiments

    NASA Technical Reports Server (NTRS)

    Jones, T. B.; Perry, M. P.

    1974-01-01

    Experiments with two electrohydrodynamic heat pipes are reported. Both devices employ an electromechanical flow structure for axial liquid flow and a capillary wicking structure for (1) collection of condensed liquid at the cooled end and (2) distribution of this liquid at the heated end. One device has circumferential grooving for the capillary structure and the other has feltmetal wicking. The experiments successfully demonstrate the electrohydrodynamic heat pipe concept. Compatibility of the two circumferential wick structures with an axial electromechanical flow structure is also demonstrated. A significant mismatch of the capillary groove and electrohydrodynamic pumping capabilities results in severe hydrodynamic burn-out limiting in the first heat pipe. Both devices have very poor over-all thermal conductances of the order of 1-2 W/deg C, reflecting the generally poor heat-transfer properties of the dielectric working fluids required in electrohydrodynamic heat pipes.

  17. Children's experiences of hospitalization.

    PubMed

    Coyne, Imelda

    2006-12-01

    This article reports on children's experiences of hospitalization. Data were collected via semi-structured interviews with 11 children aged between seven and 14 years from four paediatric units in England. The children identified a range of fears and concerns, which included: separation from parents and family; unfamiliar environment; investigations and treatments; and loss of self-determination. The children's loss of self-determination over personal needs exacerbated their fears and concerns. It needs to be recognized that compliance with hospital routines is a variable, which influences children's reaction to hospitalization. The findings clearly indicate that children need adequate information tailored to their needs, that their views are sought in the planning and delivery of their care and that hospital environments need to be made more child-centred. Interventions designed to reduce children's stress during hospitalization are not only likely to decrease their stress at the time, but also likely to influence how future experiences are appraised and managed. PMID:17101624

  18. Collaborative engagement experiment

    NASA Astrophysics Data System (ADS)

    Mullens, Katherine; Troyer, Bradley; Wade, Robert; Skibba, Brian; Dunn, Michael

    2006-05-01

    Unmanned ground and air systems operating in collaboration have the potential to provide future Joint Forces a significant capability for operations in complex terrain. Collaborative Engagement Experiment (CEE) is a consolidation of separate Air Force, Army and Navy collaborative efforts within the Joint Robotics Program (JRP) to provide a picture of the future of unmanned warfare. The Air Force Research Laboratory (AFRL), Material and Manufacturing Directorate, Aerospace Expeditionary Force Division, Force Protection Branch (AFRL/MLQF), The Army Aviation and Missile Research, Development and Engineering Center (AMRDEC) Joint Technology Center (JTC)/Systems Integration Laboratory (SIL), and the Space and Naval Warfare Systems Center - San Diego (SSC San Diego) are conducting technical research and proof of principle experiments for an envisioned operational concept for extended range, three dimensional, collaborative operations between unmanned systems, with enhanced situational awareness for lethal operations in complex terrain. This paper describes the work by these organizations to date and outlines some of the plans for future work.

  19. Vibration isolation technology experiment

    NASA Technical Reports Server (NTRS)

    Keckler, C. R.

    1984-01-01

    The objectives of the vibration isolation technology experiment are to demonstrate the viability of the magnetic suspension technology in providing the isolation of large structures elements from the external environment and to quantify the degree of isolation provided by this system. The approach proposed for this experiment is to mount a six-degrees-of-freedom magnetic bearing suspension system at the free end of a shuttle-attached flexible structure such as MAST. The disturbance generator, located on top of the isolation system, will be energized at selected and broadband frequencies to simulate a typical spacecraft vibration environment. Sensors located on the isolation system and the flexible structures element will be used to quantify the degree of isolation provided by this system.

  20. Gross decontamination experiment report

    SciTech Connect

    Mason, R.; Kinney, K.; Dettorre, J.; Gilbert, V.

    1983-07-01

    A Gross Decontamination Experiment was conducted on various levels and surfaces of the TMI - Unit 2 reactor building in March 1982. The polar crane, D-rings, missile shields, refueling canals, refueling bridges, equipment, and elevations 305' and 347'-6'' were flushed with low pressure water. Additionally, floor surfaces on elevation 305' and floor surfaces and major pieces of equipment on elevation 347'-6'' were sprayed with high pressure water. Selective surfaces were decontaminated with a mechanical scrubber and chemicals. Strippable coating was tested and evaluated on equipment and floor surfaces. The effectiveness, efficiency, and safety of several decontamination techniques were established for the large, complex decontamination effort. Various decontamination equipment was evaluated and its effectiveness was documented. Decontamination training and procedures were documented and evaluated, as were the support system and organization for the experiment.

  1. The GLORIA demonstrator experiment

    NASA Astrophysics Data System (ADS)

    Majcher, A.; ?wiek, A.; ?wiok, M.; Mankiewicz, L.; Zaremba, M.; ?arnecki, A. F.

    2013-10-01

    GLORIA stands for "GLObal Robotic-telescopes Intelligent Array" and it is the first free and open-access network of robotic telescopes on the world. Based on a Web 2.0 environment amateur and professional users can do research in astronomy by observing with robotic telescopes, and/or analyzing data acquired with GLORIA, or from other free access databases. GLORIA project develops free standards, protocols and tools for controlling Robotic Telescopes and related instrumentation, for scheduling observations in the telescope network, and for conducting so-called off-line experiments based on the analysis of astronomical data. This contribution summarizes the implementation and results from the first research level off-line demonstrator experiment implemented in GLORIA, which was base on the data collected with the "Pi of the Sky" telescope in Chile.

  2. Health Education Telecommunications Experiment

    NASA Technical Reports Server (NTRS)

    Whalen, A. A.

    1975-01-01

    The Health/Education Telecommunications Experiment carried out with Applications Technology Satellite-6 is described. The experiment tested the effectiveness of color television broadcasts to over 120 low-cost receivers in rural areas. Five types of earth stations were involved: receive-only terminals (ROT), an intensive terminal consisting of the ROT plus a VHF transmitter and receiver; comprehensive S and C-band terminals having the capability of transmitting the video signal plus four audio channels; and the main originating stations. Additional supporting elements comprise 120 video receive terminals, 51 telephony transceivers, and 8 video originating terminals of 3 different parts. Technical parameters were measured to within 1 dB of the calculated values.

  3. TIMED solar EUV experiment

    NASA Astrophysics Data System (ADS)

    Woods, Thomas N.; Bailey, Scott M.; Eparvier, Francis G.; Lawrence, George M.; Lean, Judith; McClintock, William E.; Roble, Raymond G.; Rottman, Gary J.; Solomon, Stanley C.; Tobiska, W. K.; Ucker, Gregory J.; White, O. R.

    1998-11-01

    The solar EUV experiment (SEE) selected for the NASA Thermosphere, Ionosphere, and Mesosphere Energetics and Dynamics mission will measure the solar vacuum UV (VUV) spectral irradiance from 0.1 to 200 nm. To cover this wide spectral range two different types of instruments are used: grating spectrograph for spectra above 25 nm and a set of silicon soft x-ray (XUV) photodiodes with thin film filters for below 30 nm. Redundant channels of the spectrograph and XUV photodiodes provide in-flight calibration checks on the time scale of a week, and annual rocket underflight measurements provide absolute calibration checks traceable to radiometric standards. Both types of instrument have been developed and flight proven as part of a NASA solar EUV irradiance rocket experiment.

  4. Electronics for Satellite Experiments

    SciTech Connect

    Johnson, Robert P.; /UC, Santa Cruz

    2006-05-16

    The tracking detector for the LAT science instrument on the GLAST mission is an example of a large-scale particle detection system built primarily by particle physicists for space flight within the context of a NASA program. The design and fabrication model in most ways reflected practice and experience from particle physics, but the quality assurance aspects were guided by NASA. Similarly, most of the electronics in the LAT as a whole were designed and built by staff at a particle physics lab. This paper reports on many of the challenges and lessons learned in the experience of designing and building the tracking detector and general LAT electronics for use in the NASA GLAST mission.

  5. White Cliffs: Operating Experience

    NASA Technical Reports Server (NTRS)

    Kaneff, S.

    1984-01-01

    The fourteen dish white cliffs solar power station area is remote and subject to extreme environmental conditions, solution of the associated problems required careful and thoughtful attention and the application of resources. Notwithstanding the wide range and harshness of conditions, the difficulties caused by remoteness and the lack of a technological base and the need for relatively rapid demonstration of success, the project has had a very positive outcome. Qualitative and quantitative information and lessons are now available to enable considerable simplifications to be made for a new system, reducing both hardware and operation and maintenance costs. Experience and lessons are presented, particularly in relation to: system performance in various environmental conditions; design philosophies for collectors, the array, control systems, engine and plant; operation and maintenance strategies and cost reducing possibilities. Experience so far gives encouragement for the future of such paraboloidal dish systems in appropriate areas.

  6. Modeling Mendel's Pea Experiment

    NSDL National Science Digital Library

    Jeanette Nolin

    2009-01-01

    This modeling activity allows learners to discover for themselves what Mendel uncovered in his famous pea experiments. By modeling Mendel's pea experiments, learners will form their own explanations for the result of crossing a true-breeding round pea plant with a true-breeding wrinkled pea plant (the F1 generation) and for the results of allowing an F1 pea plant to self pollinate (the F2 generation). They will then compare their explanations to Mendel's own conclusions. This is an excellent introduction to Mendelian genetics which generates discussion and stimulates interest in Mendel's principles. Learners are encouraged to use the same observation and critical thinking skills that Mendel used. This activity can be instructor-led as a demonstration or conducted by groups of learners.

  7. Make and Take Experiment

    NSDL National Science Digital Library

    The Materials Science and Technology Teacher's Workshop (MAST) provides this experiment on concrete in construction. The experiment focuses on developing an understanding of concrete as a construction material. Concrete products will be designed and constructed. Students will use two different sized containers that fit concentrically inside one another to create an enlarged crucible or planter box shape. Concrete will then be poured into that container and the concrete part will be allowed to cure. No testing will be done with this part, it is simply and exercise used to practice the preparation and execution of making concrete structures.The lesson includes a step by step explanation of the laboratory procedure, teacher notes and a link to a video clip. The exercise should take about 45 minutes of class time.

  8. New experiments with antiprotons

    E-print Network

    Daniel M. Kaplan

    2010-07-30

    Fermilab operates the world's most intense antiproton source. Recently proposed experiments can use those antiprotons either parasitically during Tevatron Collider running or after the Tevatron Collider finishes in about 2011. For example, the annihilation of 8 GeV antiprotons might make the world's most intense source of tagged D^0 mesons, and thus the best near-term opportunity to study charm mixing and search for new physics via its CP-violation signature. Other possible precision measurements include properties of the X(3872) and the charmonium system. An experiment using a Penning trap and an atom interferometer could make the world's first measurement of the gravitational force on antimatter. These and other potential measurements using antiprotons could yield a broad physics program at Fermilab in the post-Tevatron era.

  9. New experiments with antiprotons

    E-print Network

    ,

    2010-01-01

    Fermilab operates the world's most intense antiproton source. Recently proposed experiments can use those antiprotons either parasitically during Tevatron Collider running or after the Tevatron Collider finishes in about 2011. For example, the annihilation of 8 GeV antiprotons might make the world's most intense source of tagged D^0 mesons, and thus the best near-term opportunity to study charm mixing and search for new physics via its CP-violation signature. Other possible precision measurements include properties of the X(3872) and the charmonium system. An experiment using a Penning trap and an atom interferometer could make the world's first measurement of the gravitational force on antimatter. These and other potential measurements using antiprotons could yield a broad physics program at Fermilab in the post-Tevatron era.

  10. New Experiments with Antiprotons

    E-print Network

    Daniel M. Kaplan

    2011-01-06

    Fermilab operates the world's most intense antiproton source. Newly proposed experiments can use those antiprotons either parasitically during Tevatron Collider running or after the Tevatron Collider finishes. For example, the annihilation of 8 GeV antiprotons is expected to yield world-leading sensitivities to hyperon rare decays and CP violation. It could also provide the world's most intense source of tagged D^0 mesons, and thus the best near-term opportunity to study charm mixing and, via CP violation, to search for new physics. Other precision measurements that could be made include properties of the X(3872) and the charmonium system. An experiment using a Penning trap and an atom interferometer could make the world's first measurement of the gravitational force on antimatter. These and other potential measurements using antiprotons could lead to a broad physics program at Fermilab in the post-Tevatron era.

  11. New Experiments with Antiprotons

    E-print Network

    Kaplan, Daniel M

    2011-01-01

    Fermilab operates the world's most intense antiproton source. Newly proposed experiments can use those antiprotons either parasitically during Tevatron Collider running or after the Tevatron Collider finishes. For example, the annihilation of 8 GeV antiprotons is expected to yield world-leading sensitivities to hyperon rare decays and CP violation. It could also provide the world's most intense source of tagged D^0 mesons, and thus the best near-term opportunity to study charm mixing and, via CP violation, to search for new physics. Other precision measurements that could be made include properties of the X(3872) and the charmonium system. An experiment using a Penning trap and an atom interferometer could make the world's first measurement of the gravitational force on antimatter. These and other potential measurements using antiprotons could lead to a broad physics program at Fermilab in the post-Tevatron era.

  12. AGS Experiments: 1989, 1990, 1991

    SciTech Connect

    Depken, J.C.

    1992-02-01

    This report contains: Experimental areas layout; table of beam parameters and fluxes; experiment schedule as run''; proposed 1992 schedule; a listing of experiments by number; two-page summaries of each experiment begin here, also ordered by number; publications of AGS Experiments begin here; and list of AGS Experimenters begins here.

  13. AGS Experiments: 1989, 1990, 1991

    SciTech Connect

    Depken, J.C.

    1992-02-01

    This report contains: Experimental areas layout; table of beam parameters and fluxes; experiment schedule ``as run``; proposed 1992 schedule; a listing of experiments by number; two-page summaries of each experiment begin here, also ordered by number; publications of AGS Experiments begin here; and list of AGS Experimenters begins here.

  14. Convergence of Quantum Statistical Experiments

    E-print Network

    Guta, Madalin

    Convergence of Quantum Statistical Experiments M!d!lin Gu"! University of Nottingham Jonas Kahn (Paris-Sud) Anna Jen#ová (Bratislava) Richard Gill (Leiden) #12;Statistical experiments and statistical decision problems Statistical experiment · Measure space: (, , P) · Statistical experiment over (dominated

  15. Designing and Conducting Phishing Experiments

    Microsoft Academic Search

    Peter Finn; Markus Jakobsson

    We describe ethical and procedural aspects of setting up and con- ducting phishing experiments, drawing on experience gained from being involved in the design and execution of a sequence of phishing experi- ments (second author), and from being involved in the review of such experiments at the Institutional Review Board (IRB) level (first author). We describe the roles of consent,

  16. The Blowgun Demonstration Experiment

    ERIC Educational Resources Information Center

    Tsukamoto, Koji; Uchino, Masanori

    2008-01-01

    We have found that a simple demonstration experiment using a match or a cotton swab and a drinking straw or an acrylic pipe serves as an effective introduction to dynamics. The most basic apparatus has a cotton swab serving as a dart and the straw as the blowgun. When blown from a starting point near the exit end of the straw, the cotton swab does…

  17. Bean Bag Experiment

    NSDL National Science Digital Library

    2012-06-26

    In this activity (located on pages 21-22 of PDF), learners explore inclined planes. Learners conduct an experiment using a large beanbag chair (or trash bag filled with coats or pillows) and a set of stairs to see how inclined planes make work easier. Learners discover that it requires less force to roll the bean bag down an inclined plane than throwing it between students.

  18. STELLA Experiment - Microbunch Diagnostic

    SciTech Connect

    He, P.; Liu, Y.; Cline, D. B.; Babzien, M.; Gallardo, J. C.; Kusche, K. P.; Pogorelsky, I. V.; Skaritka, J.; van Steenbergen, A.; Yakimenko, V.; Kimura, W. D.

    1998-07-01

    A microbunch diagnostic system is built at the Accelerator Test Facility (ATF) of Brookhaven National Laboratory for monitoring microbunches (10-fs bunch length) produced by the Inverse Free Electron Laser accelerator in Staged Electron Laser Acceleration experiment. It is similar to one already demonstrated at the ATF. With greatly improved beam optics conditions higher order harmonic coherent transition radiation will be measurable to determine the microbunch length and shape.

  19. An analemma experiment

    NASA Astrophysics Data System (ADS)

    Davis, Dan M.

    2000-12-01

    I describe here a very simple experiment that allows a science class to measure the latitude of their school, determine the inclination of the Earth's axis to the ecliptic, and demonstrate the noncircularity of our orbit around the Sun. The only tools needed are: something tall and pointed (a flagpole will do), paint and a paint brush, a tape measure, a watch, and an accurate way of finding the time (such as a radio).

  20. The BLAST experiment

    Microsoft Academic Search

    D. Hasell; T. Akdogan; R. Alarcon; W. Bertozzi; E. Booth; T. Botto; J. R. Calarco; B. Clasie; C. Crawford; A. Degrush; K. Dow; D. Dutta; M. Farkhondeh; R. Fatemi; O. Filoti; W. Franklin; H. Gao; E. Geis; S. Gilad; W. Hersman; M. Holtrop; E. Ihloff; P. Karpius; J. Kelsey; M. Kohl; H. Kolster; S. Krause; T. Lee; A. Maschinot; J. Matthews; K. McIlhany; N. Meitanis; R. Milner; J. Rapaport; R. Redwine; J. Seely; A. Sindile; S. Širca; T. Smith; S. Sobczynski; M. Tanguay; B. Tonguc; C. Tschalaer; E. Tsentalovich; W. Turchinetz; J. van der Laan; F. Wang; T. Wise; Y. Xiao; W. Xu; C. Zhang; Z. Zhou; V. Ziskin; T. Zwart

    2009-01-01

    The Bates large acceptance spectrometer toroid (BLAST) experiment was operated at the MIT-Bates Linear Accelerator Center from 2003 until 2005. The detector and experimental program were designed to study, in a systematic manner, the spin-dependent electromagnetic interaction in few-nucleon systems. As such the data will provide improved measurements for neutron, proton, and deuteron form factors. The data will also allow

  1. The Ediacaran experiment.

    PubMed

    Gould, S J

    1984-02-01

    The author reflects on presentations at an annual meeting of the Geological Society of America regarding the differences between Ediacaran fauna fossils and fossils from the Cambrian evolutionary explosion. The theory presented by Dolf Seilacher attributes the differences between Ediacaran animals and their modern counterparts to structure. He proposes that Ediacaran fauna were a failed evolutionary experiment. Related comments and meeting presentations are included. PMID:11541840

  2. TRIO-01 experiment

    SciTech Connect

    Clemmer, R.G.; Finn, P.A.; Billone, M.C.; Misra, B.; Greenwood, L.R.; Dyer, F.F.; Dudley, I.T.; Bate, L.C.; Clemmer, E.D.; Fisher, P.W.

    1984-02-10

    The TRIO-01 experiment was designed to test in-situ tritium recovery and heat transfer performance of a candidate solid breeder, ..gamma..-LiAlO/sub 2/. The results showed that nearly all the tritium generated was recovered. Only <0.1 wppM tritium remained in the solid after irradiation testing. The heat transfer performance showed that temperature profiles can be effectively controlled.

  3. TRIO01 experiment

    Microsoft Academic Search

    R. G. Clemmer; P. A. Finn; M. C. Billone; B. Misra; L. R. Greenwood; F. F. Dyer; I. T. Dudley; L. C. Bate; E. D. Clemmer; P. W. Fisher

    1984-01-01

    The TRIO-01 experiment was designed to test in-situ tritium recovery and heat transfer performance of a candidate solid breeder, ..gamma..-LiAlOâ. The results showed that nearly all the tritium generated was recovered. Only <0.1 wppM tritium remained in the solid after irradiation testing. The heat transfer performance showed that temperature profiles can be effectively controlled.

  4. NPB cesium space experiment

    NASA Astrophysics Data System (ADS)

    Parsons, George M., III

    Neutral Particle Beam (NPB) weapons systems are planned to perform the ballistic missile defense functions of nuclear weapon/decoy discrimination and warhead kill at appropriate energy levels and ion currents. Negatively charged ions are produced in a specialized ion source and focused into a high quality particle beam. NPB linear accelerators accelerate and steer the negatively charged ions using electric and magnetic fields. After acceleration and steering the neutralizer system strips away extra electrons from ions to form the electrically neutral particle beam. The neutral beam then travels through space to the target unaffected by the Earth's magnetic fields. Continuing technological advances have greatly reduced the size and weight of NPB accelerator systems. Ion current production has been enhanced by over 100 percent with the intermittent addition of cesium at the NPB ion source device. This increase in current is essential to attain the most light weight, compact NPB platforms and minimize expensive launch costs. Addition of cesium into the ion source has been identified by the NPB community as the highest priority risk reduction space experiment necessary prior to planned NPB accelerator experiments and later weapons systems. The NPB Cesium Space Experiment is planned to successfully demonstrate controlled cesium introduction and vaporization into a simulated ion source chamber. Microgravity effects on the cesium deposition will be studied as will the effects of small amounts of cesium on high voltage accelerator components that might be susceptible to electrical insulator break downs. The experiment design will simulate as closely as possible the environment, physical and operational characteristics of the actual NPB ion source.

  5. Newton's Second Law Experiment

    NSDL National Science Digital Library

    Fendt, Walter

    This applet simulates an experiment to study Newton's Second Law. A mass sliding on a horizontal surface is connected by a string to a hanging mass. The value of the two masses and the coefficient of friction can be set by the user. The user can use a timer to gather data for the motion of the sliding mass as a function of time. This applet is a part of a large collection of physics applets, available in a wide range of languages.

  6. Martian Regolith Analog Experiments

    Microsoft Academic Search

    M. A. McGraw; D. B. Reisenfeld; L. R. Stupin; B. J. Travis

    2004-01-01

    We describe a set of laboratory experiments designed to investigate Martian regolith hydrodynamics and to test the MAGHNUM computer model. A previous study with MAGHNUM (JGR-Planets 108: 8040-8054) indicated that if H2O is present in the Martian regolith, as is widely believed, then liquid water could be present beneath the cryosphere and it should be in a convective state, locally

  7. Red and Black Experiment

    NSDL National Science Digital Library

    Kyle Siegrist

    This resource consists of a Java applet and expository text. The applet simulates the red and black experiment in which a player bets on a sequence of Bernoulli trials until a target fortune is reached or the player is ruined. The initial fortune, target fortune, and trial win probability can be varied, and the user can select either of two basic strategies: timid play or bold play.

  8. Monty Hall Experiment

    NSDL National Science Digital Library

    Kyle Siegrist

    This resource consists of a Java applet and expository text. The applet is a simulation of the Monty Hall experiment: a car is behind one door, goats are behind the other two doors. The player chooses a door and then the host opens another door. The player is given the option of switching to the remaining door. The stochastic behavior of the host and the probability of the player switching can be specified.

  9. The Double Chooz experiment

    Microsoft Academic Search

    T. Akiri

    2011-01-01

    Double Chooz is a neutrino oscillation experiment that will measure the last unknown mixing angle theta or improve the current best limit by almost an order of magnitude. Its potential is a measurement at 3sigma if sin22theta=>0.05 or an exclusion down to 0.03 at 90% C.L. for Deltam312=2.5×10-3eV2. In this paper, the experimental concept, the detector design and status are

  10. LLNL experience with HIPPI

    SciTech Connect

    Getchell, D.

    1991-10-01

    The High Performance Switching System Program (HPSS) at the Lawrence Livermore National Laboratory is in the process of implementing a gigabit Local Area Network featuring cross bar switches that interface to HIPPI, VME, and NuBus adapters. This paper presents a brief review of the design of the HPSS network, discusses our experiences with using HIPPI as an interconnect in a Local Area Network and describes our efforts to achieve maximum performance from our Model C and D IOS Cray systems.

  11. TFTR DT experiments

    Microsoft Academic Search

    J. D. Strachan; S. Batha; M. Beer; M. G. Bell; R. E. Bell; A. Belov; H. Berk; S. Bernabei; M. Bitter; B. Breizman; N. L. Bretz; R. Budny; C. E. Bush; J. Callen; S. Cauffman; C. S. Chang; Z. Chang; C. Z. Cheng; D. S. Darrow; R. O. Dendy; W. Dorland; H. Duong; P. C. Efthimion; D. Ernst; H. Evenson; N. J. Fisch; R. Fisher; R. J. Fonck; E. D. Fredrickson; G. Y. Fu; H. P. Furth; N. N. Gorelenkov; V. Ya Goloborod'ko; B. Grek; L. R. Grisham; G. W. Hammett; R. J. Hawryluk; W. Heidbrink; H. W. Herrmann; M. C. Herrmann; W A Houlberg; J. Hogan; B. Hooper; J. C. Hosea; M. Hughes; D. L. Jassby; F. C. Jobes; D. W. Johnson; R. Kaita; S. Kaye; J. Kesner; J. S. Kim; M. Kissick; A. V. Krasilnikov; H. Kugel; A. Kumar; N. T. Lam; P. Lamarche; B. Leblanc; F. M. Levinton; C. Ludescher; J. Machuzak; R. P. Majeski; J. Manickam; D. K. Mansfield; M. Mauel; E. Mazzucato; J. McChesney; D. C. McCune; G. McKee; K. M. McGuire; D. M. Meade; S. S. Medley; D. R. Mikkelsen; S. V. Mirnov; D. Mueller; Y. Nagayama; G. A. Navratil; R. Nazikian; M. Okabayashi; M. Osakabe; D. K. Owens; H. K. Park; S. F. Paul; M. P. Petrov; C. K. Phillips; M. Phillips; P. Phillips; A. T. Ramsey; B. Rice; M. H. Redi; G. Rewoldt; S. Reznik; A. L. Roquemore; J. Rogers; E. Ruskov; S. A. Sabbagh; M. Sasao; G. Schilling; G. L. Schmidt; S. D. Scott; I. Semenov; T. Senko; C. H. Skinner; T. Stevenson; E. J. Strait; B. C. Stratton; W. Stodiek; E. Synakowski; H. Takahashi; W. Tang; G. Taylor; M. E. Thompson; S. von Goeler; A. von Halle; R. T. Walters; S. Wang; R. White; R. M. Wieland; M. Williams; J. R. Wilson; K. L. Wong; G. A. Wurden; M. Yamada; V. Yavorski; K. M. Young; L. Zakharov; M. C. Zarnstorff; S. J. Zweben

    1997-01-01

    The Tokamak Fusion Test Reactor (TFTR) is a large tokamak which has performed experiments with 50:50 deuterium - tritium fuelled plasmas. Since 1993, TFTR has produced about 1090 D - T plasmas using about 100 grams of tritium and producing about 1.6 GJ of D - T fusion energy. These plasmas have significant populations of 3.5 MeV alphas (the charged

  12. Pitch Memory Experiment

    NSDL National Science Digital Library

    This is the entry page for the Pitch Memory Experiment. The pitch memory task is patterned after Deutsch (1979). On each trial, a target tone and a test tone are presented with five distracter tones between them. Participants will be asked to judge whether the target and test tones are the same or different. There are 38 trials when the tones are the same and 38 when they are different.

  13. Mirror Drawing Experiment

    NSDL National Science Digital Library

    Maureen McCarthy

    2006-01-18

    This is the entry page for participation in the Mirror Drawing Experiment. This study is designed to demonstrate that for right-handed people, who comprise over 90% of the population, the right hemisphere performs visual spatial tasks better than the left hemisphere. For most right-handers, whereas the left hemisphere excels in verbal and analytical tasks, the right hemisphere specializes in emotional, nonverbal, and visual-spatial tasks.

  14. The PAMELA Space Experiment

    Microsoft Academic Search

    E. Mocchiutti; O. Adriani; G. C. Barbarino; G. A. Bazilevskaya; R. Bellotti; M. Boezio; E. A. Bogomolov; L. Bonechi; M. Bongi; V. Bonvicini; S. Borisov; S. Bottai; A. Bruno; F. Cafagna; D. Campana; R. Carbone; P. Carlson; M. Casolino; G. Castellini; M. P. De Pascale; N. De Simone; V. Di Felice; A. M. Galper; W. Gillard; L. Grishantseva; P. Hofverberg; G. Jerse; S. V. Koldashov; S. Y. Krutkov; A. N. Kvashnin; A. Leonov; O. Maksumov; V. Malvezzi; L. Marcelli; W. Menn; V. V. Mikhailov; N. N. Nikonov; G. Osteria; P. Papini; M. Pearce; P. Picozza; M. Ricci; S. B. Ricciarini; L. Rossetto; M. Runtso; M. Simon; R. Sparvoli; P. Spillantini; Y. I. Stozhkov; A. Vacchi; E. Vannuccini; G. Vasilyev; S. A. Voronov; J. Wu; Y. T. Yurkin; G. Zampa; N. Zampa; V. G. Zverev

    2009-01-01

    The 15th of June 2006, the PAMELA satellite-borne experiment was launched from the Baikonur cosmodrome and it has been collecting data since July 2006. The apparatus comprises a time-of-flight system, a silicon-microstrip magnetic spectrometer, a silicon-tungsten electromagnetic calorimeter, an anticoincidence system, a shower tail counter scintillator and a neutron detector. The combination of these devices allows precision studies of the

  15. IRTube: Infrared Imaging Experiments

    NSDL National Science Digital Library

    The Concord Consortium

    This website is a collection of easy-to-do experiments which use an affordable handheld IR camera (under $900) to visualize invisible energy flows and transformations. Using this "desktop remote sensing" approach, thermal energy can be readily "seen." Other types of energy that convert into thermal energy can be inferred from thermal signals. Hence, many invisible physical, chemical, and biological processes that absorb or release heat can be visualized, discovered, and investigated.

  16. Apollo lunar sounder experiment

    USGS Publications Warehouse

    Phillips, R.J.; Adams, G.F.; Brown, W.E., Jr.; Eggleton, R.E.; Jackson, P.; Jordan, R.; Linlor, W.I.; Peeples, W.J.; Porcello, L.J.; Ryu, J.; Schaber, G.; Sill, W.R.; Thompson, T.W.; Ward, S.H.; Zelenka, J.S.

    1973-01-01

    The scientific objectives of the Apollo lunar sounder experiment (ALSE) are (1) mapping of subsurface electrical conductivity structure to infer geological structure, (2) surface profiling to determine lunar topographic variations, (3) surface imaging, and (4) measuring galactic electromagnetic radiation in the lunar environment. The ALSE was a three-frequency, wide-band, coherent radar system operated from lunar orbit during the Apollo 17 mission.

  17. Separated quadrupolar field experiment.

    PubMed

    Kumar, Rajeev; Ling, Wen; Schoefberger, Wolfgang; Jerschow, Alexej

    2005-02-01

    We describe an NMR experiment that produces spectra correlating the first-order quadrupolar spectrum and the central transition spectrum of half-integer quadrupolar spins, allowing one to separate the quadrupolar parameters in overlapping spectra under both static and magic-angle-spinning conditions. Promising fields of applications include situations where the sample cannot easily be rotated, or where it cannot be rotated at the magic angle. PMID:15649747

  18. Omniscience and experience

    Microsoft Academic Search

    Marcel Sarot

    1991-01-01

    My conclusions are the following:(1)We can distinguish between two sorts of kowledge: intellectual knowledge (knowledge of true propositions) and experiential knowledge (knowledge of how certain experiences feel).(2)If we want the doctrine of divine omniscience to be theologically relevant, we will have to assert that divine omniscience involves experiential as well as intellectual omniscience.(3)In order to be omniscient, God does not

  19. Delivering ideal employee experiences.

    PubMed

    Weiss, Marjorie D; Tyink, Steve; Kubiak, Curt

    2009-05-01

    Employee-centric strategies have moved from employee satisfaction and brand awareness to employee "affinity" or "attachment." In today's marketplace, occupational health nurses understand that differentiation (i.e., the perception of uniqueness) is the direct result of superior employee interactions, which lead to better employee care, enduring employee relationships, loyal employees, and satisfied employers. What drives employees to occupational health nurse attachment? The answer is a passion for rising above the competition to create ideal employee experiences. PMID:19492760

  20. FIRST EXPERIENCES WITH THE \\

    Microsoft Academic Search

    André Streilein; Klaus Hanke; Pierre Grussenmeyer

    In this paper we report about first results and experiences using this CIPA reference data set for digital close-range photogrammetry. Results derived with different commercial or educational packages are presented. These different software packages follow different photogrammetric strategies (e.g. number of images used, stereo\\/non-stereo, bundle adjustment). The involved software packages are Canoma, Photomodeler, and Tiphon-Arpenteur. The different results are summarised

  1. Stress and Strain Experiment

    NSDL National Science Digital Library

    The Materials Science and Technology Teacher's Workshop (MAST) provides this experiment as an introduction to stress and strain. The lesson allows students the opportunity to "design and make a concrete cylinder and beam that can withstand the greatest applied load." The concepts of comprehensive and tensile stress are incorporated into the lesson plan. Links to useful video clips, diagrams and discussion questions are included. The exercise should take about 90 minutes of class time.

  2. Air Gun Experiment

    NSDL National Science Digital Library

    NASA

    This video shows an impact experiment of a high-speed impact into a frozen comet-like material (dust, ice, window cleaner and Worcestershire sauce) over a highly porous target (garden perlite). The impact makes a small hole in the comet, simulating a strength-controlled crater, but a large crater grows below and peals back the surface crust like petals of a flower. The result is similar to a deeply buried explosion.

  3. The Double Chooz Experiment

    NASA Astrophysics Data System (ADS)

    Pfahler, Patrick; Double Chooz Collaboration

    2012-07-01

    Double Chooz is a reactor bar nue-disappearance experiment situated at the commercial nuclear power plant of Chooz in northern France. The experiment aims for the revelation of the last unknown mixing angle ?13 as a part of the neutrino mixing matrix or the improvement of the upper limit for sin2(2?13), which is currently < 0.14 (90% CL). A newly developed gadolinium-loaded liquid scintillator as target allows the detection of electron-anti-neutrinos (bar nue) using the inverse beta decay and its distinct decay pattern (bar nue + p ? e+ +n). Double Chooz uses two identical detectors at different distances in order to reduce systematic uncertainties. This will allow, after a data taking phase of 4 years, an improvement on sin2(2?13) down to < 0.03 (90% CL). The first (far) detector has successfully been installed and filled, and takes data since April of 2011. A preliminary analysis of first 120 days revealed about 4000 Neutrino-candidates and a stable detector-setup with low backgrounds. The commissioning of the second (near) detector is expected for the beginning of 2013 and will provide maximum sensitivity for the experiment.

  4. The MATERHORN Experiment

    NASA Astrophysics Data System (ADS)

    Retallack, C.; Fernando, H.; Pardyjak, E.; De Wekker, S.; Pace, J. C.

    2011-12-01

    A comprehensive field experimental program is planned to study flow over mountainous terrain. This experiment is a part of the Mountain Terrain Atmospheric Modeling and Observations (MATERHORN) program, funded under the Multidisciplinary University Research Initiative Program, to improve mountain terrain weather forecasting. The participants include the University of Notre Dame, Naval Research Laboratory, Naval Post Graduate School, University of California, Berkeley, University of Utah, University of Virginia, and US Army Dugway Proving Ground. The experiments will be conducted at the Granite Mountain Atmospheric Science Testbed (GMAST) at the US Army Dugway Proving Ground. GMAST is conceivably the most heavily instrumented test bed for studying atmospheric processes within complex-terrain. In addition to the vast array of permanent monitoring devices located at GMAST, several pieces of sophisticated remote and in-situ atmospheric measurement devices will be installed in the vicinity of Granite Mountain. The first of the two field campaigns will take place during spring 2012 focusing on moist soil conditions and frequent synoptic disturbances. The second field campaign will take place during fall 2012 under drier and more quiescent conditions. These studies aim to characterize surface conditions related to mountain winds, investigate the planetary boundary layer in complex-terrain, study surface exchange processes, and to observe the interaction of flows across a wide range of space-time scales. Data collected will be used for model evaluation and data assimilation. The design of the experiment will be described in this paper.

  5. Shared Experience: Art & War

    NSDL National Science Digital Library

    2006-01-01

    The use of artistic expression to convey the experience of war and the battlefield has been around since antiquity, and has given rise to glorious poetry, epic stories, and more recently, paintings. This online exhibit created by the people at the Australian War Memorial presents the experiences of Australians, Britons, and Canadians in the Second World War through paintings created during this turbulent period. As the homepage suggests, "The men and women that feature in these works are shown waiting, preparing, fighting, suffering, celebrating". First-time visitors will want to start by reading the introductory essay by Roger Tolson titled "A Shared Experience". After doing so, they should feel free to browse around the paintings offered here, all of which are grouped into thematic categories that include "Casualties", "Work", and "Battle". There are a number of rather haunting and evocative paintings scattered across these categories, but visitors should be sure to take a look at the work "Battlefield burial of three NCOs" by Ivor Hele and "Airmen In A Village Pub Yorkshire" by Miller Brittain. The site is rounded by brief biographies for each of the artists whose work is included on the site.

  6. Experiments with Electrodynamic Wheels

    NASA Astrophysics Data System (ADS)

    Gaul, Nathan; Corey, Daniel; Cordrey, Vincent; Majewski, Walerian

    2015-04-01

    Our experiments were involving inductive magnetic levitation. A Halbach array is a system in which a series of magnets is arranged in a manner such that the magnetic field is cancelled on one side of the array while strengthening the field on the other. We constructed two circular Halbach wheels, making the strong magnetic field on the outer rim of the ring. Such system is usually dubbed as an Electrodynamic Wheel (EDW). Rotating this wheel around a horizontal axis above a flat conducting surface should induce eddy currents in said surface through the variable magnetic flux. The eddy currents produce, in turn, their own magnetic fields which interact with the magnets of the EDW. We demonstrated that these interactions produce both drag and lift forces on the EDW which can theoretically be used for lift and propulsion of the EDW. The focus of our experiments is determining how to maximize the lift-to-drag ratio by the proper choice of the induction element. We will also describe our experiments with a rotating circular Halbach array having the strong magnetic field of about 1 T on the flat side of the ring, and acting as a hovercraft.

  7. Calabi-Yau manifolds in weighted P4

    Microsoft Academic Search

    P. Candelas; M. Lynker; R. Schimmrigk

    1990-01-01

    It has recently been recognized that the relation between exactly solvable conformal field theory compactifications of the Heterotic String and Calabi-Yau manifolds necessarily involves the discussion of embeddings in weighted projective space. We therefore study this class of manifolds more closely. We have constructed a subclass of these spaces and find that this class features a surprising symmetry under chi

  8. Pion elastic scattering from ?p4?sHe 

    E-print Network

    Mahmoud, Ahmed Mohamed

    1990-01-01

    " that we were not able to reproduce with our wave function. Q VERSUS F 1 ? -coef. O ~~10' IX O 10 0. 1. 2. 3. 4 5. 6, 7. 8. 9. 10. 1 1, Q' (fm ') Fig. 1. Single term fit to electron scattering data. He form factor vs Q svhere Q is in the range of 0... . 10fm Q VERSUS F 3 ? ? t-oef, CL I- O f 10' CL O 10 0. 1. 2. 3, 4. 5. 6. 7. 8. 9. 10. 11. Q (fm ) Fig. 2. Single term fit to electron scattering data. He form factor vs Q where Q is in the range of 0 0. 3fm Q VERSUS F 1 ? ? coef. IX I? O O...

  9. p. 2--GCR Executive columns p.4--Arrivals and Returns

    E-print Network

    Wirosoetisno, Djoko

    Walking to work today in my new winter coat and hat it's difficult to remember that only a few, short everyone involved in the ten days of Induction `Week'. It wouldn't have been possible without the dozens, representation and welfare support that can benefit all students in Ustinov. Chairperson's Report Iain Wallace

  10. (continued on page 2) Research Highlights ................. (p. 4)

    E-print Network

    structure is important. The Forest Service is comprised of three major branches: the National Forest System management, cred- ible science is prerequisite to informed public discourse. This lynx research by Forest Burcham) Leonard F. Ruggiero, Deputy Program Manager, Wildlife and Terrestrial Habitats Science Program

  11. Energies and E1, M1, E2, and M2 transition rates for states of the 2s22p3, 2s2p4, and 2p5 configurations in nitrogen-like ions between F III and Kr XXX

    NASA Astrophysics Data System (ADS)

    Rynkun, P.; Jönsson, P.; Gaigalas, G.; Froese Fischer, C.

    2014-03-01

    Based on relativistic wavefunctions from multiconfiguration Dirac-Hartree-Fock and configuration interaction calculations, E1, M1, E2, and M2 transition rates, weighted oscillator strengths, and lifetimes are evaluated for the states of the (1s2)2s22p3,2s2p4, and 2p5 configurations in all nitrogen-like ions between F III and Kr XXX. The wavefunction expansions include valence, core-valence, and core-core correlation effects through single-double multireference expansions to increasing sets of active orbitals. The computed energies agree very well with experimental values, with differences of only 300-600 cm-1 for the majority of the levels and ions in the sequence. Computed transitions rates are in close agreement with available data from MCHF-BP calculations by Tachiev and Froese Fischer [G.I. Tachiev, C. Froese Fischer, A&A 385 (2002) 716].

  12. Collaborative engagement experiment (CEE)

    NASA Astrophysics Data System (ADS)

    Wade, Robert L.; Reames, Joseph M.

    2005-05-01

    Unmanned ground and air systems operating in collaboration have the potential to provide future Joint Forces a significant capability for operations in complex terrain. Ground and air collaborative engagements potentially offer force conservation, perform timely acquisition and dissemination of essential combat information, and can eliminate high value and time critical targets. These engagements can also add considerably to force survivability by reducing soldier and equipment exposure during critical operations. The Office of the Secretary of Defense, Joint Robotics Program (JRP) sponsored Collaborative Engagement Experiment (CEE) is a consolidation of separate Air Force, Army and Navy collaborative efforts to provide a Joint capability. The Air Force Research Laboratory (AFRL), Material and Manufacturing Directorate, Aerospace Expeditionary Force Division, Force Protection Branch (AFRLMLQF), The Army Aviation and Missile Research, Development and Engineering Center (AMRDEC) Joint Technology Center (JTC)/Systems Integration Laboratory (SIL), and the Space and Naval Warfare Systems Center-San Diego (SSC San Diego) are conducting technical research and proof of principle for an envisioned operational concept for extended range, three dimensional, collaborative operations between unmanned systems, with enhanced situational awareness for lethal operations in complex terrain. This program will assess information requirements and conduct experiments to identify and resolve technical risks for collaborative engagements using Unmanned Ground Vehicles (UGVs) and Unmanned Aerial Vehicles (UAVs). It will research, develop and physically integrate multiple unmanned systems and conduct live collaborative experiments. Modeling and Simulation systems will be upgraded to reflect engineering fidelity levels to greater understand technical challenges to operate as a team. This paper will provide an update of a multi-year program and will concentrate primarily on the JTC/SIL efforts. Other papers will outline in detail the Air Force and Navy portions of this effort.

  13. Situating emotional experience

    PubMed Central

    Wilson-Mendenhall, Christine D.; Barrett, Lisa Feldman; Barsalou, Lawrence W.

    2013-01-01

    Psychological construction approaches to emotion suggest that emotional experience is situated and dynamic. Fear, for example, is typically studied in a physical danger context (e.g., threatening snake), but in the real world, it often occurs in social contexts, especially those involving social evaluation (e.g., public speaking). Understanding situated emotional experience is critical because adaptive responding is guided by situational context (e.g., inferring the intention of another in a social evaluation situation vs. monitoring the environment in a physical danger situation). In an fMRI study, we assessed situated emotional experience using a newly developed paradigm in which participants vividly imagine different scenarios from a first-person perspective, in this case scenarios involving either social evaluation or physical danger. We hypothesized that distributed neural patterns would underlie immersion in social evaluation and physical danger situations, with shared activity patterns across both situations in multiple sensory modalities and in circuitry involved in integrating salient sensory information, and with unique activity patterns for each situation type in coordinated large-scale networks that reflect situated responding. More specifically, we predicted that networks underlying the social inference and mentalizing involved in responding to a social threat (in regions that make up the “default mode” network) would be reliably more active during social evaluation situations. In contrast, networks underlying the visuospatial attention and action planning involved in responding to a physical threat would be reliably more active during physical danger situations. The results supported these hypotheses. In line with emerging psychological construction approaches, the findings suggest that coordinated brain networks offer a systematic way to interpret the distributed patterns that underlie the diverse situational contexts characterizing emotional life. PMID:24324420

  14. Situating emotional experience.

    PubMed

    Wilson-Mendenhall, Christine D; Barrett, Lisa Feldman; Barsalou, Lawrence W

    2013-01-01

    Psychological construction approaches to emotion suggest that emotional experience is situated and dynamic. Fear, for example, is typically studied in a physical danger context (e.g., threatening snake), but in the real world, it often occurs in social contexts, especially those involving social evaluation (e.g., public speaking). Understanding situated emotional experience is critical because adaptive responding is guided by situational context (e.g., inferring the intention of another in a social evaluation situation vs. monitoring the environment in a physical danger situation). In an fMRI study, we assessed situated emotional experience using a newly developed paradigm in which participants vividly imagine different scenarios from a first-person perspective, in this case scenarios involving either social evaluation or physical danger. We hypothesized that distributed neural patterns would underlie immersion in social evaluation and physical danger situations, with shared activity patterns across both situations in multiple sensory modalities and in circuitry involved in integrating salient sensory information, and with unique activity patterns for each situation type in coordinated large-scale networks that reflect situated responding. More specifically, we predicted that networks underlying the social inference and mentalizing involved in responding to a social threat (in regions that make up the "default mode" network) would be reliably more active during social evaluation situations. In contrast, networks underlying the visuospatial attention and action planning involved in responding to a physical threat would be reliably more active during physical danger situations. The results supported these hypotheses. In line with emerging psychological construction approaches, the findings suggest that coordinated brain networks offer a systematic way to interpret the distributed patterns that underlie the diverse situational contexts characterizing emotional life. PMID:24324420

  15. Experience the Moon

    NASA Astrophysics Data System (ADS)

    Ortiz-Gil, A.; Benacchio, L.; Boccato, C.

    2011-10-01

    The Moon is, together with the Sun, the very first astronomical object that we experience in our life. As this is an exclusively visual experience, people with visual impairments need a different mode to experience it too. This statement is especially true when events, such as more and more frequent public observations of sky, take place. This is the reason why we are preparing a special package for visual impaired people containing three brand new items: 1. a tactile 3D Moon sphere in Braille with its paper key in Braille. To produce it we used imaging data obtained by NASA's mission Clementine, along with free image processing and 3D rendering software. In order to build the 3D small scale model funding by Europlanet and the Italian Ministry for Research have been used. 2. a multilingual web site for visually impaired users of all ages, on basic astronomy together with an indepth box about the Moon; 3. a book in Braille with the same content of the Web site mentioned above. All the items will be developed with the collaboration of visually impaired people that will check each step of the project and support their comments and criticism to improve it. We are going to test this package during the next International Observe the Moon Night event. After a first testing phase we'll collect all the feedback data in order to give an effective form to the package. Finally the Moon package could be delivered to all those who will demand it for outreach or educational goals.

  16. Southeast Regional Experiment Station

    NASA Astrophysics Data System (ADS)

    1994-08-01

    This is the final report of the Southeast Regional Experiment Station project. The Florida Solar Energy Center (FSEC), a research institute of the University of Central Florida (UCF), has operated the Southeast Regional Experiment Station (SE RES) for the US Department of Energy (DOE) since September 1982. Sandia National Laboratories, Albuquerque (SNLA) provides technical program direction for both the SE RES and the Southwest Regional Experiment Station (SW RES) located at the Southwest Technology Development Institute at Las Cruces, New Mexico. This cooperative effort serves a critical role in the national photovoltaic program by conducting system evaluations, design assistance and technology transfer to enhance the cost-effective utilization and development of photovoltaic technology. Initially, the research focus of the SE RES program centered on utility-connected PV systems and associated issues. In 1987, the SE RES began evaluating amorphous silicon (a-Si) thin-film PV modules for application in utility-interactive systems. Stand-alone PV systems began receiving increased emphasis at the SE RES in 1986. Research projects were initiated that involved evaluation of vaccine refrigeration, water pumping and other stand-alone power systems. The results of this work have led to design optimization techniques and procedures for the sizing and modeling of PV water pumping systems. Later recent research at the SE RES included test and evaluation of batteries and charge controllers for stand-alone PV system applications. The SE RES project provided the foundation on which FSEC achieved national recognition for its expertise in PV systems research and related technology transfer programs. These synergistic products of the SE RES illustrate the high visibility and contributions the FSEC PV program offers to the DOE.

  17. The LUX Experiment

    NASA Astrophysics Data System (ADS)

    Akerib, D. S.; Araújo, H. M.; Bai, X.; Bailey, A. J.; Balajthy, J.; Bernard, E.; Bernstein, A.; Bradley, A.; Byram, D.; Cahn, S. B.; Carmona-Benitez, M. C.; Chan, C.; Chapman, J. J.; Chiller, A. A.; Chiller, C.; Coffey, T.; Currie, A.; de Viveiros, L.; Dobi, A.; Dobson, J.; Druszkiewicz, E.; Edwards, B.; Faham, C. H.; Fiorucci, S.; Flores, C.; Gaitskell, R. J.; Gehman, V. M.; Ghag, C.; Gibson, K. R.; Gilchriese, M. G. D.; Hall, C.; Hertel, S. A.; Horn, M.; Huang, D. Q.; Ihm, M.; Jacobsen, R. G.; Kazkaz, K.; Knoche, R.; Larsen, N. A.; Lee, C.; Lindote, A.; Lopes, M. I.; Malling, D. C.; Mannino, R.; McKinsey, D. N.; Mei, D.-M.; Mock, J.; Moongweluwan, M.; Morad, J.; Murphy, A. St. J.; Nehrkorn, C.; Nelson, H.; Neves, F.; Ott, R. A.; Pangilinan, M.; Parker, P. D.; Pease, E. K.; Pech, K.; Phelps, P.; Reichhart, L.; Shutt, T.; Silva, C.; Solovov, V. N.; Sorensen, P.; O'Sullivan, K.; Sumner, T. J.; Szydagis, M.; Taylor, D.; Tennyson, B.; Tiedt, D. R.; Tripathi, M.; Uvarov, S.; Verbus, J. R.; Walsh, N.; Webb, R.; White, J. T.; Witherell, M. S.; Wolfs, F. L. H.; Woods, M.; Zhang, C.

    We present the status and prospects of the LUX experiment, which employs approximately 300 kg of two-phase xenon to search for WIMP dark matter interactions. The LUX detector was commissioned at the surface laboratory of the Sanford Underground Research Facility in Lead, SD, between December 2011 and February 2012 and the detector has been operating underground since January, 2013. These proceedings review the results of the commissioning run as well as the status of underground data-taking through the summer of 2013.

  18. Muller Lyer Experiment

    NSDL National Science Digital Library

    This is the entry page for the Muller Lyer Experiment. The study contained in this collection is a variation of the original Müller-Lyer illusion, one which enables investigators to study the effect of changes in fin angle on the apparent length of lines. Participants in the study are presented with two lines, as in the standard Müller-Lyer presentation, but one of the lines has fins and one does not. The participant's task is to adjust the plain line (without fins) to make the lengths the same.

  19. NASA's supercomputing experience

    NASA Technical Reports Server (NTRS)

    Bailey, F. Ron

    1990-01-01

    A brief overview of NASA's recent experience in supercomputing is presented from two perspectives: early systems development and advanced supercomputing applications. NASA's role in supercomputing systems development is illustrated by discussion of activities carried out by the Numerical Aerodynamical Simulation Program. Current capabilities in advanced technology applications are illustrated with examples in turbulence physics, aerodynamics, aerothermodynamics, chemistry, and structural mechanics. Capabilities in science applications are illustrated by examples in astrophysics and atmospheric modeling. Future directions and NASA's new High Performance Computing Program are briefly discussed.

  20. Initial blood storage experiment

    NASA Technical Reports Server (NTRS)

    Surgenor, Douglas MACN.

    1988-01-01

    The possibility of conducting experiments with the formed elements of the blood under conditions of microgravity opens up important opportunities to improve the understanding of basic formed element physiology, as well as, contribution to improved preservation of the formed elements for use in transfusion. The physiological, biochemical, and physical changes of the membrane of the erythrocyte, platelet, and leukocyte was studied during storage under two specific conditions: standard blood bank conditions and microgravity, utilizing three FDA approved plastic bags. Storage lesions; red cell storage on Earth; platelet storage on Earth; and leukocyte storage Earth were examined. The interaction of biomaterials and blood cells was studied during storage.

  1. Design for Aesthetic Experience

    Microsoft Academic Search

    Po-Hsien Lin; Chi-Chang Lu; Mo-Li Yeh

    \\u000a Taiwanese government has been aggressively promoting culture creative industries in recent years. To achieve the goals of\\u000a industry transformation and to better the living environment, it further propels the innovative concept of “creative life\\u000a industry”.\\u000a \\u000a \\u000a Demonstrating a new economy model, creative life industry intends to attain experience economy through attracting consumers\\u000a with life aesthetics. In human life, craft creation comes

  2. Women's Experience of Miscarriage

    PubMed Central

    Manca, Donna P.; Bass, Martin J.

    1991-01-01

    Physicians lack knowledge on how to help women who have miscarried deal with their emotional distress. We interviewed 16 women 4 and 12 weeks after a miscarriage. The women described their experience of miscarriage and perceptions of what helped or hindered their emotional recovery, particularly physicians' actions. A grief reaction that can be divided into five stages and that was modified through the support of family and friends was identified. The intensity of the grief was related to the personal meaning of the pregnancy. PMID:21229103

  3. The double chooz experiment

    NASA Astrophysics Data System (ADS)

    Collin, A. P.; Double Chooz Collaboration

    2013-10-01

    The Double Chooz experiment observed an indication of reactor ¯?e disappearance consistent with neutrino oscillations at 1050 m from two reactors. During the first 101 days of data taking, the ratio of observed to expected events assuming no oscillation amount to 0.944 ± 0.016 (stat) ± 0.040 (syst). Combined with energy spectrum information, this deficit leads to sin2(2?13) = 0.086±0.041(stat)±0.030(syst), excluding the no oscillation hypothesis at the 94.6% C.L.

  4. The Double Chooz Experiment

    NASA Astrophysics Data System (ADS)

    Cabrera, A.; Double Chooz Collaboration

    2012-08-01

    The Double Chooz neutrino oscillations experiment is expected to measure, or limit, the unmeasured leptonic mixing angle ?13 using neutrinos from the Chooz reactor complex (France). The experimental technique relies on two detectors to reduce the so far dominating neutrino flux uncertainty as well as backgrounds. The DC sensitivity (at 90%CL) is sin2(2?13)<0.054 and sin2(2?13)<0.030, for the far detector only (1.5 years) and near/far detectors (3 years), respectively. The far detector is to be filled and completed by the end 2010, while data taking has started since June 2010 (without scintillator).

  5. Results of railgun experiments

    SciTech Connect

    Hawke, R.S.; Brooks, A.L.; Fowler, C.M.; Peterson, D.R.

    1983-04-01

    During the 1979 Megagauss II conference the hypervelocity potential of railguns and the pulsed power technology needed to power them were discussed. Since then, many laboratories have initiated railgun R and D projects for a variety of potential applications. Los Alamos and Lawrence Livermore National Laboratories initiated a collaborative experimental railgun project which resulted in several successes in accelerating projectiles to high velocities, emphasized the limits on railgun operation, and indicated that the numerical modeling of railgun operation was in good agreement with the experiments.

  6. Rotational fluid flow experiment

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This project which began in 1986 as part of the Worcester Polytechnic Institute (WPI) Advanced Space Design Program focuses on the design and implementation of an electromechanical system for studying vortex behavior in a microgravity environment. Most of the existing equipment was revised and redesigned by this project team, as necessary. Emphasis was placed on documentation and integration of the electrical and mechanical subsystems. Project results include reconfiguration and thorough testing of all hardware subsystems, implementation of an infrared gas entrainment detector, new signal processing circuitry for the ultrasonic fluid circulation device, improved prototype interface circuits, and software for overall control of experiment operation.

  7. Magnetohydrodynamic Augmented Propulsion Experiment

    NASA Technical Reports Server (NTRS)

    Litchford, Ron J.; Cole, John; Lineberry, John; Chapman, Jim; Schmidt, Harold; Cook, Stephen (Technical Monitor)

    2002-01-01

    A fundamental obstacle to routine space access is the specific energy limitations associated with chemical fuels. In the case of vertical take-off, the high thrust needed for vertical liftoff and acceleration to orbit translates into power levels in the 10 GW range. Furthermore, useful payload mass fractions are possible only if the exhaust particle energy (i.e., exhaust velocity) is much greater than that available with traditional chemical propulsion. The electronic binding energy released by the best chemical reactions (e.g., LOX/LH2 for example, is less than 2 eV per product molecule (approx. 1.8 eV per H2O molecule), which translates into particle velocities less than 5 km/s. Useful payload fractions, however, will require exhaust velocities exceeding 15 km/s (i.e., particle energies greater than 20 eV). As an added challenge, the envisioned hypothetical RLV (reusable launch vehicle) should accomplish these amazing performance feats while providing relatively low acceleration levels to orbit (2-3g maximum). From such fundamental considerations, it is painfully obvious that planned and current RLV solutions based on chemical fuels alone represent only a temporary solution and can only result in minor gains, at best. What is truly needed is a revolutionary approach that will dramatically reduce the amount of fuel and size of the launch vehicle. This implies the need for new compact high-power energy sources as well as advanced accelerator technologies for increasing engine exhaust velocity. Electromagnetic acceleration techniques are of immense interest since they can be used to circumvent the thermal limits associated with conventional propulsion systems. This paper describes the Magnetohydrodynamic Augmented Propulsion Experiment (MAPX) being undertaken at NASA Marshall Space Flight Center (MSFC). In this experiment, a 1-MW arc heater is being used as a feeder for a 1-MW magnetohydrodynamic (MHD) accelerator. The purpose of the experiment is to demonstrate that an MHD accelerator can be an effective augmentation system for increasing engine exhaust velocity. More specifically, the experiment is intended to show that electromagnetic effects are effective at producing flow acceleration whereas electrothermal effects do not cause unacceptable heating of the working fluid. The MHD accelerator was designed as an externally diagonalized segmented Faraday channel, which will be inserted into an existing 2-tesla electromagnet. This allows the external power to be connected through two terminals thereby minimizing the complexity and cost associated with powering each segment independently. The design of the accelerator and other components in the flow path has been completed and fabrication activities are underway. This paper provides a full description of MAPX including performance analysis, design, and test plans, and current status.

  8. Swine Feeding Experiments

    E-print Network

    Warren, G. R. (George Russell); Williams, D. W. (David Willard)

    1923-01-01

    feeds used were corn chops, milo chops, rice bran, and rice polish. One lot was finished on peanut grazing alone, one lot was partly finished on peanuts and completed on a grain ration, and three lots were finished on free-choice self-feeders. , A11... experiments herein reported were conducted at the Feeding and Breeding Station, Substation No. 10, College Station, Texas. In most cases the lots have been fed at a profit over feed costs. It is thought advisable to submit the result!: in the form of tables...

  9. Experiences with solar power

    NASA Astrophysics Data System (ADS)

    Kesselring, P.

    1985-11-01

    Experience with solar thermal plants is reviewed. The component and subsystems development of the last decade and particularly the receiver, collector and heliostat field development is a technical success. Solar specific problems on the system and component level arose, when off the shelf solutions of fossile fired plants were transferred uncritically. It is shown that concentrated solar radiation is a relatively cheap high quality fuel. Other uses than electricity generation are high temperature processes and the production of solar fuels and chemicals. A technical and economic comparison of solar thermal and photovoltaic electricity generation is made.

  10. Large lithium loop experience

    SciTech Connect

    Kolowith, R.; Owen, T.J.; Berg, J.D.; Atwood, J.M.

    1981-10-01

    An engineering design and operating experience of a large, isothermal, lithium-coolant test loop are presented. This liquid metal coolant loop is called the Experimental Lithium System (ELS) and has operated safely and reliably for over 6500 hours through September 1981. The loop is used for full-scale testing of components for the Fusion Materials Irradiation Test (FMIT) Facility. Main system parameters include coolant temperatures to 430/sup 0/C and flow to 0.038 m/sup 3//s (600 gal/min). Performance of the main pump, vacuum system, and control system is discussed. Unique test capabilities of the ELS are also discussed.

  11. The American Experience: Houdini

    NSDL National Science Digital Library

    Come one, come all to this site on Harry Houdini, the man who escaped a locked crate lowered into the East River, the Milk Can, the Water Torture Cell, and being buried alive. This companion site to a forthcoming program in the PBS American Experience series chronicles the life of the world's greatest escape artist and one of the best showmen to grace the stage. At the site, users can trace Houdini's career, watch several video clips of his daring escapes, learn some of his secrets, and view twelve posters from his heyday. In addition, the site offers articles on the people and events featured in the program and a Teacher's Guide.

  12. Quantum frequency downconversion experiment

    E-print Network

    Hiroki Takesue

    2010-06-02

    We report the first quantum frequency downconversion experiment. Using the difference frequency generation process in a periodically poled lithium niobate waveguide, we successfully observed the phase-preserved frequency downconversion of a coherent pulse train with an average photon number per pulse of $<$1, from the 0.7-$\\mu$m visible wavelength band to the 1.3-$\\mu$m telecom band. We expect this technology to become an important tool for flexible photonic quantum networking, including the realization of quantum repeater systems over optical fiber using atom-photon entanglement sources for the visible wavelength bands.

  13. Soil mechanics experiment

    NASA Technical Reports Server (NTRS)

    Mitchell, J. K.; Bromwell, L. G.; Carrier, W. D., III; Costes, N. C.; Houston, W. N.; Scott, R. F.

    1972-01-01

    The Apollo 15 soil-mechanics experiment has offered greater opportunity for study of the mechanical properties of the lunar soil than previous missions, not only because of the extended lunar-surface stay time and enhanced mobility provided by the lunar roving vehicle (rover), but also because four new data sources were available for the first time. These sources were: (1) the self-recording penetrometer (SRP), (2) new, larger diameter, thin-walled core tubes, (3) the rover, and (4) the Apollo lunar-surface drill (ALSD). These data sources have provided the best bases for quantitative analyses thus far available in the Apollo Program.

  14. Olympus propagation experiments

    NASA Technical Reports Server (NTRS)

    Arbesser-Rastburg, Bertram

    1994-01-01

    A summary of the activities of the OPEX (Olympus Propagation EXperimenters) group is given and some of the recent findings are presented. OLYMPUS, a telecommunication satellite owned by the European Space Agency, was launched on 12 June 1989. After the in-orbit tests were completed (in September 1989) the first propagation experiments started. Throughout 1990 the spacecraft functioned very well and a large number of experimenters received the beacon signals. On 29 May 1991 the spacecraft became inoperational after a major technical problem. With a series of complicated procedures OLYMPUS was recovered on 15 August 1991 - the first time in history that a civilian telecommunications satellite was brought back to service after losing power and telemetry. The propagation experiments were back on track. However, the recovery had used up so much fuel that the North-South station keeping had to be abandoned, which led to a natural increase of inclination at a rate of about 0.8 deg per year. On 10 October 1992 the second 30 GHz beacon tube failed, causing a loss of this beacon signal. The other two beacon frequencies continued to deliver a stable signal for more than two years. On 12 August 1993 the spacecraft experienced another problem with the altitude control, but this time there was not enough fuel left for a recovery maneuver and thus the mission came to an end.

  15. The Halogen Occultation Experiment

    NASA Technical Reports Server (NTRS)

    Russell, James M., III; Gordley, Larry L.; Park, Jae H.; Drayson, S. R.; Hesketh, W. D.; Cicerone, Ralph J.; Tuck, Adrian F.; Frederick, John E.; Harries, John E.; Crutzen, Paul J.

    1993-01-01

    The Halogen Occultation Experiment (HALOE) uses solar occultation to measure vertical profiles of O3, HCl, HF, CH4, H2O, NO, NO2, aerosol extinction, and temperature versus pressure with an instantaneous vertical field of view of 1.6 km at the earth limb. Latitudinal coverage is from 80 deg S to 80 deg N over the course of 1 year and includes extensive observations of the Antarctic region during spring. The altitude range of the measurements extends from about 15 km to about 60-130 km, depending on channel. Experiment operations have been essentially flawless, and all performance criteria either meet or exceed specifications. Internal data consistency checks, comparisons with correlative measurements, and qualitative comparisons with 1985 atmospheric trace molecule spectroscopy (ATMOS) results are in good agreement. Examples of pressure versus latitude cross sections and a global orthographic projection for the September 21 to October 15, 1992, period show the utility of CH4, HF, and H2O as tracers, the occurrence of dehydration in the Antarctic lower stratosphere, the presence of the water vapor hygropause in the tropics, evidence of Antarctic air in the tropics, the influence of Hadley tropical upwelling, and the first global distribution of HCl, HF, and NO throughout the stratosphere. Nitric oxide measurements extend through the lower thermosphere.

  16. An Experiment in Synchronicity

    NASA Astrophysics Data System (ADS)

    Thomson, S.; Dunseath, W. J. R.

    Click here and insert your abstract text. Possible states theory generalizes about the process of change within a finite and discrete model of the universe. The possible states consist of all interactions between objects, including past, future and possible interactions. The theory posits a non-electromagnetic model of change in which change propagates without reference to space-time. The theory delivers verifiable predictions and is generally consistent with quantum theory. It offers the prospect of nonlocal connections between objects and change that is not constrained by conservation laws. The value of the concept as a basis for technology development depends upon the ability to manipulate the possible states, specifically to produce coherence in selected collections of states. An experiment is devised in which a coherent state path is created between the experimental components and loaded through interaction with non-coherent states. Discharge of coherence results in a burst of synchronistic events compatible with theoretical expectations. The experiment validates a specific control strategy and yields a large timewise anomaly. The results shed light on a potential sentient intelligence and upon the development of coherence in the possible states and enable a major advance in the control of change.

  17. Rapid decisions from experience.

    PubMed

    Zeigenfuse, Matthew D; Pleskac, Timothy J; Liu, Taosheng

    2014-05-01

    In many everyday decisions, people quickly integrate noisy samples of information to form a preference among alternatives that offer uncertain rewards. Here, we investigated this decision process using the Flash Gambling Task (FGT), in which participants made a series of choices between a certain payoff and an uncertain alternative that produced a normal distribution of payoffs. For each choice, participants experienced the distribution of payoffs via rapid samples updated every 50ms. We show that people can make these rapid decisions from experience and that the decision process is consistent with a sequential sampling process. Results also reveal a dissociation between these preferential decisions and equivalent perceptual decisions where participants had to determine which alternatives contained more dots on average. To account for this dissociation, we developed a sequential sampling rank-dependent utility model, which showed that participants in the FGT attended more to larger potential payoffs than participants in the perceptual task despite being given equivalent information. We discuss the implications of these findings in terms of computational models of preferential choice and a more complete understanding of experience-based decision making. PMID:24549141

  18. The Nucifer Experiment

    NASA Astrophysics Data System (ADS)

    Cucoanes, A. S.

    2014-06-01

    In nuclear reactors, a large number of antineutrinos are generated in the decay chains of the fission products; thus a survey of the antineutrino flux could provide valuable information related to the uranium and plutonium content of the core. This application generated interest by the IAEA in using antineutrino detectors as a potential safeguard tool. Here we present the Nucifer experiment, developed in France, by CEA and CNRS/IN2P3. The design of this new antineutrino detector has focused on safety, size reduction, reliability and high detection efficiency with a good background rejection. The Nucifer detector is currently taking data at the OSIRIS research reactor, inside CEA-Saclay. Presently, the ongoing analyses are considering the main sources of background for the antineutrino detection; the first antineutrino result is expected in 2013. A possible contribution to the understanding of the so called “reactor antineutrino anomaly” is also discussed. Finally, we present a brief description of the proposed experiments at very short baselines (VSBL) from reactors in France.

  19. The Halogen Occultation Experiment

    NASA Astrophysics Data System (ADS)

    Russell, James M., III; Gordley, Larry L.; Park, Jae H.; Drayson, S. R.; Hesketh, W. D.; Cicerone, Ralph J.; Tuck, Adrian F.; Frederick, John E.; Harries, John E.; Crutzen, Paul J.

    1993-06-01

    The Halogen Occultation Experiment (HALOE) uses solar occultation to measure vertical profiles of O3, HCl, HF, CH4, H2O, NO, NO2, aerosol extinction, and temperature versus pressure with an instantaneous vertical field of view of 1.6 km at the earth limb. Latitudinal coverage is from 80 deg S to 80 deg N over the course of 1 year and includes extensive observations of the Antarctic region during spring. The altitude range of the measurements extends from about 15 km to about 60-130 km, depending on channel. Experiment operations have been essentially flawless, and all performance criteria either meet or exceed specifications. Internal data consistency checks, comparisons with correlative measurements, and qualitative comparisons with 1985 atmospheric trace molecule spectroscopy (ATMOS) results are in good agreement. Examples of pressure versus latitude cross sections and a global orthographic projection for the September 21 to October 15, 1992, period show the utility of CH4, HF, and H2O as tracers, the occurrence of dehydration in the Antarctic lower stratosphere, the presence of the water vapor hygropause in the tropics, evidence of Antarctic air in the tropics, the influence of Hadley tropical upwelling, and the first global distribution of HCl, HF, and NO throughout the stratosphere. Nitric oxide measurements extend through the lower thermosphere.

  20. Rapid Decisions From Experience

    PubMed Central

    Zeigenfuse, Matthew D.; Pleskac, Timothy J.; Liu, Taosheng

    2014-01-01

    In many everyday decisions, people quickly integrate noisy samples of information to form a preference among alternatives that offer uncertain rewards. Here, we investigated this decision process using the Flash Gambling Task (FGT), in which participants made a series of choices between a certain payoff and an uncertain alternative that produced a normal distribution of payoffs. For each choice, participants experienced the distribution of payoffs via rapid samples updated every 50 ms. We show that people can make these rapid decisions from experience and that the decision process is consistent with a sequential sampling process. Results also reveal a dissociation between these preferential decisions and equivalent perceptual decisions where participants had to determine which alternatives contained more dots on average. To account for this dissociation, we developed a sequential sampling rank-dependent utility model, which showed that participants in the FGT attended more to larger potential payoffs than participants in the perceptual task despite being given equivalent information. We discuss the implications of these findings in terms of computational models of preferential choice and a more complete understanding of experience-based decision making. PMID:24549141

  1. Female physicist doctoral experiences

    NASA Astrophysics Data System (ADS)

    Dabney, Katherine P.; Tai, Robert H.

    2013-06-01

    The underrepresentation of women in physics doctorate programs and in tenured academic positions indicates a need to evaluate what may influence their career choice and persistence. This qualitative paper examines eleven females in physics doctoral programs and professional science positions in order to provide a more thorough understanding of why and how women make career choices based on aspects both inside and outside of school and their subsequent interaction. Results indicate that female physicists experience conflict in achieving balance within their graduate school experiences and personal lives and that this then influences their view of their future careers and possible career choices. Female physicists report both early and long-term support outside of school by family, and later departmental support, as being essential to their persistence within the field. A greater focus on informal and out-of-school science activities for females, especially those that involve family members, early in life may help influence their entrance into a physics career later in life. Departmental support, through advisers, mentors, peers, and women’s support groups, with a focus on work-life balance can help females to complete graduate school and persist into an academic career.

  2. Visual Experiences during Paralysis

    PubMed Central

    Whitham, Emma M.; Fitzgibbon, Sean P.; Lewis, Trent W.; Pope, Kenneth J.; DeLosAngeles, Dylan; Clark, C. Richard; Lillie, Peter; Hardy, Andrew; Gandevia, Simon C.; Willoughby, John O.

    2011-01-01

    Rationale: Paralyzed human volunteers (n?=?6) participated in several studies the primary one of which required full neuromuscular paralysis while awake. After the primary experiment, while still paralyzed and awake, subjects undertook studies of humor and of attempted eye-movement. The attempted eye-movements tested a central, intentional component to one’s internal visual model and are the subject of this report. Methods: Subjects reclined in a supportive chair and were ventilated after paralysis (cisatracurium, 20?mg intravenously). In illumination, subjects were requested to focus alternately on the faces of investigators standing on the left and the right within peripheral vision. In darkness, subjects were instructed to look away from a point source of light. Subjects were to report their experiences after reversal of paralysis. Results: During attempted eye-movement in illumination, one subject had an illusion of environmental movement but four subjects perceived faces as clearly as if they were in central vision. In darkness, four subjects reported movement of the target light in the direction of attempted eye-movements and three could control the movement of the light at will. Conclusion: The hypothesis that internal visual models receive intended ocular-movement-information directly from oculomotor centers is strengthened by this evidence. PMID:22162967

  3. Lunar atmospheric composition experiment

    NASA Technical Reports Server (NTRS)

    Hoffman, J. H.

    1975-01-01

    Apollo 17 carried a miniature mass spectrometer, called the Lunar Atmospheric Composition Experiment (LACE), to the moon as part of the Apollo Lunar Surface Experiments Package (ALSEP) to study the composition and variations in the lunar atmosphere. The instrument was successfully deployed in the Taurus-Littrow Valley with its entrance aperture oriented upward to intercept and measure the downward flux of gases at the lunar surface. During the ten lunations that the LACE operated, it produced a large base of data on the lunar atmosphere, mainly collected at night time. It was found that thermal escape is the most rapid loss mechanism for hydrogen and helium. For heavier gases, photoionization followed by acceleration through the solar wind electric field accounted for most of the loss. The dominant gases on the moosn were argon and helium, and models formed for their distribution are described in detail. It is concluded that most of the helium in the lunar atmosphere is of solar wind origin, and that there also exist very small amounts of methane, ammonia, and carbon dioxide.

  4. The majorana experiment

    SciTech Connect

    Rielage, Keith R [Los Alamos National Laboratory; Elliott, Steven R [Los Alamos National Laboratory; Boswell, Melissa [Los Alamos National Laboratory; Gehman, Victor M [Los Alamos National Laboratory; Hime, Andrew [Los Alamos National Laboratory; Kidd, Mary F [Los Alamos National Laboratory; La Roque, Benjamin H [Los Alamos National Laboratory; Rodriguez, Larry [Los Alamos National Laboratory; Ronquest, Michael C [Los Alamos National Laboratory; Salazar, Harry [Los Alamos National Laboratory; Steele, David [Los Alamos National Laboratory

    2010-12-13

    The MAJORANA Collaboration is assembling an array of HPGe detectors to search for neutrinoless double-beta decay in {sup 76}Ge. Initially, MAJORANA aims to construct a prototype module to demonstrate the potential of a future 1-tonne experiment. The design and potential reach of this prototype DEMONSTRATOR module are presented. Our proposed method uses the well-established technique of searching for neutrinoless double-beta decay in high purity Ge-diode radiation detectors that play both roles of source and detector. The use of P-PC Ge detectors present advances in background rejection and a Significantly lower energy threshold than conventional Ge detector technologies. The lower energy threshold opens up a broader and exciting physics program including searches for dark matter and axions concurrent with the double-beta decay search. The DEMONSTRATOR should establish that the backgrounds are low enough to justify scaling to tonne-scale experiment, probe the neutrino effective mass region above 100 meV, and search the low energy region with a sensitivity to dark matter. The DEMONSTRATOR will be sited at the 4850-ft level (4200 m.w.e) of the Sanford Underground Laboratory at Homestake and preparations for construction are currently underway.

  5. Active experiments in space, laboratory experiments and numerical simulation

    Microsoft Academic Search

    I. M. Podgornyi

    1982-01-01

    Important trends in laboratory, numerical, and space experiments are outlined. Particular attention is given to the experiments of Baum and Bratenahl (1980) on current sheets and reconnection. Experimental studies dealing with critical ionization velocity and electric double layers are described. Attention is also given to experiments on electron beams in the earth's magnetosphere and plasma injection to the magnetosphere.

  6. ESA-space experiments: from BIOPAN 6 experiment

    Microsoft Academic Search

    Jean-Pierre de Vera; Silvano Onofri; Rosa de La Torre Noetzel; Laura Zucconi; Laura Selbmann; Sieglinde Ott; Rene Demets; Elke Rabbow; Gerda Horneck

    2010-01-01

    The experiment Lithopanspermia and the experiment Life: The concept of both of the space experiments is to expose different eukaryotic species as there are the lichens Xan-thoria elegans, Rhizocarpon geographicum and their mycobiont cultures, the black Antarctic microfungi Cryomyces minteri and Cryomyces antarcticus and Antarctic rocks colonized by cryptoendolithic communities. The aim behind this space research is to analyze the

  7. More Thoughts on the Aladdin Experiments Experiment Set 2

    E-print Network

    Kemner, Ken

    L8-107 March 1988 More Thoughts on the Aladdin Experiments Experiment Set 2 Keith Symon 1 to work in a regime where the theorem holds, but it has two big advantages. It allows an easy check (see. If Zt ) za' then if the experience described in Ref. 2 is a guide, if we start with a very small x

  8. The polarized SRF gun experiment

    SciTech Connect

    Kewisch,J.; Ben-Zvi, I.; Rao, T.; Burrill, A.; Pate, D.; Todd, R.; Wang, E.; Bluem, H.; Holmes, D.; Shultheiss, T.

    2008-10-01

    An experiment is under way to prove the feasibility of a super-conducting RF gun for the production of polarized electrons. We report on the progress of the experiment and on simulations predicting the possibility of success.

  9. Experiments with Disposable Hypodermic Syringes.

    ERIC Educational Resources Information Center

    Clayton, G. T.; And Others

    1988-01-01

    Lists five experiments or demonstrations involving hypodermic syringes. The titles of experiments are Boyle's Law, Charles' Law, Atmospheric Pressure, Expansion of Gases, and Boiling at Reduced Pressure. Provides a list of materials, the typical data, and graphs where appropriate. (YP)

  10. Aesthetic perception, nature and experience 

    E-print Network

    Hall, Nicole Annette

    2014-07-01

    This thesis is about the perceptual nature of aesthetic experience and the importance of nature as a paradigmatic object of aesthetic perception and aesthetic experience more broadly conceived. For this reason, it merits ...

  11. Environmental Sensitivity and Paranormal Experiences 

    E-print Network

    Massullo, Brandon

    2008-12-03

    ) these environmentally sensitive individuals are also significantly more likely to report paranormal experiences than non-sensitives. The current study set out to test the hypothesis that environmentally sensitive individuals will report more past paranormal experiences...

  12. Analytical Chemistry Role Playing Experiments

    NSDL National Science Digital Library

    2011-04-14

    This page features a number of laboratory experiments (available for download in PDF format) which allow students the opportunity to role play in groups to solve problems. Experiments involve titrations, gravimetry, atomic absorption, chromatography.

  13. Partnership in Undergraduate Research Experience

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Practical laboratory and work experience has been helpful in reinforcing the undergraduate educational experience. With limited resources, individual organizations may struggle to give a student a well rounded opportunity. Most undergraduates work within internships or cooperative educational fram...

  14. The Kansas and Minnesota experiments

    Microsoft Academic Search

    J. C. Kaimal; J. C. Wyngaard

    1990-01-01

    Two experiments conducted almost 20 years ago have come to be regarded as important milestones in boundary-layer research. This paper recounts the motivation for those experiments, describes how they were conducted, and summarizes their results.

  15. The Apollo 17 surface experiments.

    NASA Technical Reports Server (NTRS)

    Hinners, N. W.; Mason, P. V.

    1972-01-01

    Significant previous Apollo scientific results which influenced the selection of site for the Apollo 17 mission are reviewed. Apollo 17 assignments and equipment are characterized as an outgrowth of the preceding Apollo missions which is focused on the main problems of lunar form and origin. Details are given on the Apollo Lunar Surface Experiments Package (ALSEP) experiments, non-ALSEP experiments, the Lunar Seismic Profiling Experiment (LSPE), and the three periods of extravehicular activity (EVA) of Apollo 17.

  16. American Experience: Jimmy Carter

    NSDL National Science Digital Library

    Chronicling the life and times of former President Jimmy Carter is a formidable task, but the American Experience Web site established to complement the new documentary about his life offers a valuable introduction to this former peanut farmer turned global humanitarian and peace maker. Not surprisingly, the site contains a substantial amount of coverage about the Camp David Accords and the Iranian hostage crisis, two events that seem to define his time in the Oval Office. The Camp David's Legacy feature contains commentary on this historic summit meeting by political scientist Betty Glad, and 444 Days: America Reacts has media coverage (including video clips) of these traumatic events. More basic information about President Carter's life is provided in a timeline, along with a photo gallery. The site concludes with a brief essay of President Carter's many contributions to humankind in the twenty years since he left the presidency.

  17. Biography of an Experiment

    NSDL National Science Digital Library

    What is the life story of a scientific experiment? What is involved with such an undertaking? These are important questions, and they are being actively explored by undergraduates and faculty at Haverford College. This website brings together excerpts of original and influential manuscripts in the natural sciences, complete with annotations by undergraduates who have spent a semester "critically evaluating the work and assessing the authors' own perspectives." Currently, there are over a dozen documents here, including "The Invention of the Dye-sensitized Solar Cell" and "Protein folding and amyloidosis". Visitors can look at students' comments on each piece and also read short biographical profiles of each young scholar. This site may very well inspire similar initiatives at other institutions and it's inspiring to see the work of scientists as they engage in a conversation with established researchers.

  18. Cell Radiation Experiment System

    NASA Technical Reports Server (NTRS)

    Morrison, Dennis R.

    2010-01-01

    The cell radiation experiment system (CRES) is a perfused-cell culture apparatus, within which cells from humans or other animals can (1) be maintained in homeostasis while (2) being exposed to ionizing radiation during controlled intervals and (3) being monitored to determine the effects of radiation and the repair of radiation damage. The CRES can be used, for example, to determine effects of drug, radiation, and combined drug and radiation treatments on both normal and tumor cells. The CRES can also be used to analyze the effects of radiosensitive or radioprotectant drugs on cells subjected to radiation. The knowledge gained by use of the CRES is expected to contribute to the development of better cancer treatments and of better protection for astronauts, medical-equipment operators, and nuclear-power-plant workers, and others exposed frequently to ionizing radiation.

  19. [Experiences with shorter surgery].

    PubMed

    Rückert, K; Nahrstedt, U

    2001-05-01

    Through the introduction of new computer-based forms of organisation, the hospital stay for both general and visceral surgery has been significantly reduced. A short stay ward with 15 beds and a dedicated functional unit was established in 1994 where approximately 1,000 operations take place each year with a 2.3 day average hospital stay. At this center laparoscopic cholecystectomy, laparoscopic herniorrhaphy, arthroscopy and perforating vein surgery are performed on ASA-I- and ASA-II-patients. Experience indicates that patients satisfaction has dramatically increased. This is due to a shorter waiting period, a guaranteed operation in accordance with the time scheduled, a comfortable hotel-like-atmosphere and minimal hospital stay without an increase of the perioperative risk. In this way hospitals can maximize their profits using special payment arrangements (all-inclusive prices). Even after introduction of the new DRG-systems short stay surgery will be attractive considering economic aspects. PMID:11396242

  20. The Cibola flight experiment

    SciTech Connect

    Caffrey, Michael Paul [Los Alamos National Laboratory; Nelson, Anthony [Los Alamos National Laboratory; Salazar, Anthony [Los Alamos National Laboratory; Roussel - Dupre, Diane [Los Alamos National Laboratory; Katko, Kim [Los Alamos National Laboratory; Palmer, Joseph [ISE-3; Robinson, Scott [Los Alamos National Laboratory; Wirthlin, Michael [BRIGHAM YOUNG UNIV; Howes, William [BRIGHAM YOUNG UNIV; Richins, Daniel [BRIGHAM YOUNG UNIV

    2009-01-01

    The Cibola Flight Experiment (CFE) is an experimental small satellite carrying a reconfigurable processing instrument developed at the Los Alamos National Laboratory that demonstrates the feasibility of using FPGA-based high-performance computing for sensor processing in the space environment. The CFE satellite was launched on March 8, 2007 in low-earth orbit and has operated extremely well since its deployment. The nine Xilinx Virtex FPGAs used in the payload have been used for several high-throughput sensor processing applications and for single-event upset (SEU) monitoring and mitigation. This paper will describe the CFE system and summarize its operational results. In addition, this paper will describe the results from several SEU detection circuits that were performed on the spacecraft.

  1. The interstellar gas experiment

    NASA Technical Reports Server (NTRS)

    Lind, D. L.; Geiss, J.; Buehler, F.; Eugster, O.

    1992-01-01

    The Interstellar Gas Experiment (IGE) exposed thin metallic foils to collect neutral interstellar gas particles. These particles penetrate the solar system due to their motion relative to the sun. Thus, it is possible to entrap them in the collecting foils along with precipitating magnetospheric and perhaps some ambient atmospheric particles. For the entire duration of the Long Duration Exposure Facility (LDEF) mission, seven of these foils collected particles arriving from seven different directions as seen from the spacecraft. In the mass spectroscopic analysis of the noble gas component of these particles, we have detected the isotopes of He-3, He-4, Ne-20, and Ne-22. In the foil analyses carried out so far, we find a distribution of particle arrival directions which shows that a significant part of the trapped particles are indeed interstellar atoms. The analysis needed to subtract the competing fluxes of magnetospheric and atmospheric particles is still in progress.

  2. DEWFALL validation experiment designs

    SciTech Connect

    Lowry, B.; Walsh, B.

    1989-09-30

    Three experiments are proposed as tests to validate the DEWFALL analysis model for the large vessel project. This document is a very brief record of the techniques and test designs that could be used for validation of the model. Processes of the model which require validation include: (1) vaporization and recondensation of the vessel wall material due to energy transfer from the source, (2) melt and refreeze of vessel wall material, and (3) condensation and solidification of the source material. A methodology was developed to analyze the maximum thickness of material melted and vaporized with given experimental configurations and initial energies. DEWFALL reference calculations are included in an appendix to the document. 2 refs., 3 figs., 3 tabs.

  3. Water Mist Experiment

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The Water Mist commercial research program is scheduled to fly an investigation on STS-107 in 2002 in the updated Combustion Module (CM-2), a sophisticated combustion chamber plus diagnostic equipment. The Center for the Commercial Applications of Combustion in Space (CCACS), a NASA Commercial Space Center located at the Colorado School of Mines, is investigating the properties of mist fire suppression in microgravity with Industry Partner Environmental Engineering Concepts. These experiments consist of varying water droplet sizes and water mist concentrations applied to flame fronts of different propane/air mixtures. Observations from these tests will provide valuable information on the change of flame speed in the presence of water mist. Shown here is a flame front propagating through the Mist flame tube during 1-g testing at NASA/Glenn Research Center.

  4. [Our experience in endourology].

    PubMed

    Vallejo, S; Montenegro, C; Gilbert, O; Hidalgo, R; Guevara, G; Sempértegui, M

    1996-04-01

    Exposition of the experience accrued over 8 years in endo-urological procedures performed to 303 patients divided in 2 groups: Lithiasic (Group I) and Non-lithiasic (Group II) patients. Ninety-two (92) percutaneous nephrostomies in 69 patients and 235 ureteroscopies in 234 patients were accomplished, removing 324 calculi and resolving other obstructive conditions. The rate of success was 85% and 98% for the percutaneous nephrostomies and ureteroscopies, respectively. Complications were reported in 7 patients after percutaneous nephrostomy and in 14 patients during ureteroscopy. Most of these complications resolved with the use of endoscopic techniques except in two patients who required open surgery. There were no deaths in the present series. The advantages of applying this technique over the conventional one are discussed. PMID:8801799

  5. American Experience: Earth Days

    NSDL National Science Digital Library

    In late 1969, Wisconsin Senator Gaylord Nelson hired Denis Hayes to organize a national teach-in day about the importance of protecting the environment for future generations. On April 22, 1970, the first Earth Day was held and over 20 million Americans participated via a variety of celebrations and demonstrations. This website is designed to be a companion to the American Experience documentary on the history of Earth Day, and it includes a teacher's guide, several special interviews, and the documentary in its entirety. The film was directed by Robert Stone, and it serves as "a poetic meditation on man's complex relationship with nature and an engaging history...of groundbreaking eco-activism." On the homepage, visitors should also take note of the photo gallery, the interactive timeline of the modern environmental movement, and a telling interview with the father of the "Green Revolution", Norman Borlaug. Visitors are also encouraged to share their own Earth Day memories on the site.

  6. The Armstrong experiment revisited

    NASA Astrophysics Data System (ADS)

    Fuchs, Elmar C.; Wexler, Adam D.; Paulitsch-Fuchs, Astrid H.; Agostinho, Luewton L. F.; Yntema, Doekle; Woisetschläger, Jakob

    2014-04-01

    When a high-voltage direct-current is applied to two beakers filled with water or polar liquid dielectrica, a horizontal bridge forms between the two beakers. This experiment was first carried out by Lord Armstrong in 1893 and then forgotten until recently. Such bridges are stable by the action of electrohydrodynamic (EHD) forces caused by electric field gradients counteracting gravity. Due to these gradients a permanent pumping of liquid from one beaker into the other is observed. At macroscopic scale several of the properties of a horizontal water bridge can be explained by modern electrohydrodynamics, analyzing the motion of fluids in electric fields. Whereas on the molecular scale water can be described by quantum mechanics, there is a conceptual gap at mesoscopic scale which is bridged by a number of theories including quantum mechanical entanglement and coherent structures in water - theories that we discuss here. Much of the phenomenon is already understood, but even more can still be learned from it, since such "floating" liquid bridges resemble a small high voltage laboratory of their own: The physics of liquids in electric fields of some kV/cm can be studied, even long time experiments like neutron or light scattering are feasible since the bridge is in a steady-state equilibrium and can be kept stable for hours. It is also an electro-chemical reactor where compounds are transported through by the EHD flow, enabling the study of electrochemical reactions under potentials which are otherwise not easily accessible. Last but not least the bridge provides the experimental biologist with the opportunity to expose living organisms such as bacteria to electric fields without killing them, but with a significant influence on their behavior, and possibly, even on their genome.

  7. Mars aqueous chemistry experiment

    NASA Technical Reports Server (NTRS)

    Clark, Benton C.; Mason, Larry W.

    1993-01-01

    The Mars Aqueous Chemistry Experiment (MACE) is designed to conduct a variety of measurements on regolith samples, encompassing mineral phase analyses, chemical interactions with H2O, and physical properties determinations. From these data, much can be learned or inferred regarding the past weathering environment, the contemporaneous soil micro-environments, and the general chemical and physical state of the Martian regolith. By analyzing both soil and duricrust samples, the nature of the latter may become more apparent. Sites may be characterized for comparative purposes and criteria could be set for selection of high priority materials on future sample return missions. Progress for the first year MACE PIDDP is reported in two major areas of effort: (1) fluids handling concepts, definition, and breadboard fabrication and (2) aqueous chemistry ion sensing technology and test facility integration. A fluids handling breadboard was designed, fabricated, and tested at Mars ambient pressure. The breadboard allows fluid manipulation scenarios to be tested under the reduced pressure conditions expected in the Martian atmosphere in order to validate valve operations, orchestrate analysis sequences, investigate sealing integrity, and to demonstrate efficacy of the fluid handling concept. Additional fluid manipulation concepts have also been developed based on updated MESUR spacecraft definition. The Mars Aqueous Chemistry Experiment Ion Selective Electrode (ISE) facility was designed as a test bed to develop a multifunction interface for measurements of chemical ion concentrations in aqueous solution. The interface allows acquisition of real time data concerning the kinetics and heats of salt dissolution, and transient response to calibration and solubility events. An array of ion selective electrodes has been interfaced and preliminary calibration studies performed.

  8. Experiment facilities for life science experiments in space.

    PubMed

    Uchida, Satoko

    2004-11-01

    To perform experiments in microgravity environment, there should be many difficulties compared with the experiments on ground. JAXA (Japan Aerospace Exploration Agency) has developed various experiment facilities to perform life science experiments in space, such as Cell Culture Kit, Thermo Electric Incubator, Free Flow Electrophoresis Unit, Aquatic Animal Experiment Unit, and so on. The first experiment facilities were flown on Spacelab-J mission in 1992, and they were improved and modified for the 2nd International Microgravity Laboratory (IML-2) mission in 1994. Based on these experiences, some of them were further improved and flown on another missions. These facilities are continuously being improved for the International Space Station use, where high level functions and automatic operations will be required. PMID:15858360

  9. DECONSTRUCTING EXPERIENCE Pulling Crackers Apart

    E-print Network

    Dix, Alan

    and rationalising experience don't we devalue it? However, the process of analysing and deconstructing2 aesthetic experience is well established in literary, graphic and musical art. This analysis and deconstruction1 Chapter 13 DECONSTRUCTING EXPERIENCE Pulling Crackers Apart Alan Dix Lancaster University, UK

  10. Fusion Ignition Research Experiment Highlights

    E-print Network

    Fusion Ignition Research Experiment Highlights FY 2004 Fusion Ignition Research Experiment #12;Need is critically needed to advance fusion science," and recommended that: "The United States should participate in the U.S. fusion program. The scientific and technological case for adding a burning plasma experiment

  11. Understanding Human Experience Henry Kautz

    E-print Network

    Kautz, Henry

    Understanding Human Experience Henry Kautz One of the earliest goals of research in artificial intelligence was to create systems that can interpret and understand day to day human experience. Early work on the goal of building systems that understand human experience. Each of the previous barriers is weakened

  12. RUMINATION, DYSPHORIA, AND SUBJECTIVE EXPERIENCE

    Microsoft Academic Search

    JONATHAN SMALLWOOD; RORY C. O'CONNOR; DEREK HEIM

    2005-01-01

    An experiment is presented which investigated the relationship between rumination, dysphoria, and subjective experience during a short word- fragment completion task. Consistent with previous work off-task thinking, operationalized as task unrelated thought, was associated with dysphoria. By contrast, rumination was a significant predictor of task appraisal defined as task-related interference (TRI). While rumination did not directly contribute to the experience

  13. Element material experiment by EFFU

    NASA Technical Reports Server (NTRS)

    Hashimoto, Yoshihiro; Ichikawa, Masaaki; Takei, Mitsuru; Torii, Yoshihiro; Ota, Kazuo

    1995-01-01

    National Space Development Agency of JAPAN (NASDA) is planning to perform Element Material Exposure Experiment using Exposed Facility Flyer Unit (EFFU). Several materials which will be used on JEM (Japanese Experiment Module for the space station) will be exposed. Space environment monitoring is also planned in this experiment. Several ground based tests are now being performed and getting useful data.

  14. Experience Oriented Teacher Education Program.

    ERIC Educational Resources Information Center

    Dakota State Coll., Madison, SD.

    Discussed is Dakota State College's Experience Oriented Teacher Education Program designed to prepare prospective teachers through experience in addition to theory. This report describes the four major aspects of the program: participation in public school classrooms prior to student teaching, human relations training experience, field seminars,…

  15. Experiment With Time: Zographie Rediscovered

    Microsoft Academic Search

    E. MACER-STORY; Magick Mirror Communications

    An experiment intended to probe possible effects of the future discernable in past artifacts resulted in the discovery a) that an artifact found prior to planning this experiment had a meaning in terms of unique data retrieved at the time of the experiment and b) unexpected results included locating \\

  16. Experiments in Physics Physics 1291

    E-print Network

    Columbia University

    Experiments in Physics Physics 1291 General Physics I Lab Columbia University Department of Physics The laboratory experiments described in this manual are an important part of your physics course. Most of the experiments are designed to illustrate important concepts described in the lectures. Whenever possible

  17. Demystifying the Delayed Choice Experiments

    E-print Network

    Bram Gaasbeek

    2010-07-22

    The delayed choice experiments are a collection of experiments where the counterintuitive laws of quantum mechanics are manifested in a very striking way. Although the delayed choice experiments can be very accurately described with the standard framework of quantum optics, a more didactical and intuitive explanation seems not to have been given so far. In this note, we fill that gap.

  18. Thought Experiments: Determining Their Meaning

    ERIC Educational Resources Information Center

    Galili, Igal

    2009-01-01

    This paper considers thought experiment as a special scientific tool that mediates between theory and experiment by mental simulation. To clarify the meaning of thought experiment, as required in teaching science, we followed the relevant episodes throughout the history of science paying attention to the epistemological status of the performed…

  19. Experiments for a Special Day

    ERIC Educational Resources Information Center

    Gluck, Paul

    2008-01-01

    Special events like science days, teacher's meetings and physics recruiting efforts require spectacular and, if possible, interactive experiments for the audience. Based on past experience with such events, we have gathered and present here a series of demonstration experiments in mechanics, optics, waves and electricity which are suitable, and…

  20. The Experience of Liberal Education

    ERIC Educational Resources Information Center

    Ayers, Edward L.

    2010-01-01

    "Experience" is a healthy-sounding word, but what do educators really mean by it? And how do educators persuade people that higher education fosters important forms of experience, that "experience" is an integral part of any vital liberal learning? The author suggests that educators might begin by getting clearer in their own minds just what they…