Science.gov

Sample records for spectroscopic portal technology

  1. Combating the counterfeits with web portal technology

    NASA Astrophysics Data System (ADS)

    Ting, S. L.; Ip, W. H.

    2015-10-01

    Due to the globalisation of counterfeiting activities, the penetration of fake products in open market is growing. So far, the technologies to combat counterfeiting are mostly applied to high-value products (e.g. premium wine and branded handbags); however, in the medium- and low-value products' perspective, there is no secure way for consumers to identify whether the purchased items are genuine or not. To address the counterfeiting problems effectively, a platform for identifying authenticated products and promoting anti-counterfeit activities is very important. The aim of this paper is to design and develop an anti-counterfeit platform which includes two functions: providing customers a secure network to ascertain the genuineness of their purchased product and increasing public awareness of the current counterfeit problems and updated anti-counterfeit solutions. By combining these two functions, it enables public to fight against fake and beware of counterfeit. Results of adopting portal technology in anti-counterfeiting show high accuracy in product checking and improved creditability. This reveals that the applicability and advantage of the proposed methodology are satisfactory.

  2. A Bayesian sequential processor approach to spectroscopic portal system decisions

    SciTech Connect

    Sale, K; Candy, J; Breitfeller, E; Guidry, B; Manatt, D; Gosnell, T; Chambers, D

    2007-07-31

    The development of faster more reliable techniques to detect radioactive contraband in a portal type scenario is an extremely important problem especially in this era of constant terrorist threats. Towards this goal the development of a model-based, Bayesian sequential data processor for the detection problem is discussed. In the sequential processor each datum (detector energy deposit and pulse arrival time) is used to update the posterior probability distribution over the space of model parameters. The nature of the sequential processor approach is that a detection is produced as soon as it is statistically justified by the data rather than waiting for a fixed counting interval before any analysis is performed. In this paper the Bayesian model-based approach, physics and signal processing models and decision functions are discussed along with the first results of our research.

  3. Integrating Space Communication Network Capabilities via Web Portal Technologies

    NASA Technical Reports Server (NTRS)

    Johnston, Mark D.; Lee, Carlyn-Ann; Lau, Chi-Wung; Cheung, Kar-Ming; Levesque, Michael; Carruth, Butch; Coffman, Adam; Wallace, Mike

    2014-01-01

    We have developed a service portal prototype as part of an investigation into the feasibility of using Java portlet technology as a means of providing integrated access to NASA communications network services. Portal servers provide an attractive platform for this role due to the various built-in collaboration applications they can provide, combined with the possibility to develop custom inter-operating portlets to extent their functionality while preserving common presentation and behavior. This paper describes various options for integration of network services related to planning and scheduling, and results based on use of a popular open-source portal framework. Plans are underway to develop an operational SCaN Service Portal, building on the experiences reported here.

  4. An overview of Grid portal technologies for the development of HMR science gateways

    NASA Astrophysics Data System (ADS)

    D'Agostino, D.

    2012-04-01

    Grid portals and related technologies represent an easy and transparent way for scientists to interact with Distributed Computing Infrastructures (DCIs) as the Grid and the Cloud. Many toolkits and frameworks are available, both commercial and open source, but there is a lack of best practices, customization methodologies and dedicated high-level service repositories that allow a fast development of specialized scientific gateways in Europe. Starting from the US TeraGrid-XSEDE experience, in this contribution the most interesting portal toolkits and related European projects are analyzed with the perspective to develop a science gateway for HMR community within the the Distributed Research Infrastructure for Hydrometeorology (DRIHM) project.

  5. Web Portals & Higher Education: Technologies To Make IT Personal. The Jossey-Bass Higher and Adult Education Series.

    ERIC Educational Resources Information Center

    Katz, Richard N., Ed.

    The chapters of this collection examine a full range of issues that any educational institution must consider before beginning to develop a Web portal, including business challenges, organizational implications, policy choices, and technology concerns. The chapters are: (1) "It's a Bird! It's a Plane! It's a Portal?" (Richard N. Katz); (2)…

  6. The Clinical Proteomic Technologies for Cancer | Antibody Portal

    Cancer.gov

    An objective of the Reagents and Resources component of NCI's Clinical Proteomic Technologies for Cancer Initiative is to generate highly characterized monoclonal antibodies to human proteins associated with cancer.

  7. Energy Innovation Portal Brings DOE Technologies to the Market (Fact Sheet)

    SciTech Connect

    Not Available

    2011-10-01

    For venture capitalists, energy entrepreneurs, and industry veterans, finding the right renewable energy or energy efficiency solution used to be like looking for a needle in a haystack. Now, a searchable treasure trove of innovative U.S. Department of Energy (DOE) technologies is available. Created by the National Renewable Energy Laboratory (NREL), the online Energy Innovation Portal helps businesses and entrepreneurs access the intellectual property of DOE's 17 national laboratories and other research partners.

  8. Adapting Corporate Portal Technology for Management E-Learning.

    ERIC Educational Resources Information Center

    Hamlin, Michael D.; Griffy-Brown, Charla

    As the largest provider of MBA talent in the Western United States, the Graziadio School of Business and Management (Malibu, California) had a need to create a technology infrastructure to support students and staff distributed in seven educational centers throughout California. This paper describes the process by which the School came to…

  9. Secure portal.

    SciTech Connect

    Nelson, Cynthia Lee

    2007-09-01

    There is a need in security systems to rapidly and accurately grant access of authorized personnel to a secure facility while denying access to unauthorized personnel. In many cases this role is filled by security personnel, which can be very costly. Systems that can perform this role autonomously without sacrificing accuracy or speed of throughput are very appealing. To address the issue of autonomous facility access through the use of technology, the idea of a ''secure portal'' is introduced. A secure portal is a defined zone where state-of-the-art technology can be implemented to grant secure area access or to allow special privileges for an individual. Biometric technologies are of interest because they are generally more difficult to defeat than technologies such as badge swipe and keypad entry. The biometric technologies selected for this concept were facial and gait recognition. They were chosen since they require less user cooperation than other biometrics such as fingerprint, iris, and hand geometry and because they have the most potential for flexibility in deployment. The secure portal concept could be implemented within the boundaries of an entry area to a facility. As a person is approaching a badge and/or PIN portal, face and gait information can be gathered and processed. The biometric information could be fused for verification against the information that is gathered from the badge. This paper discusses a facial recognition technology that was developed for the purposes of providing high verification probabilities with low false alarm rates, which would be required of an autonomous entry control system. In particular, a 3-D facial recognition approach using Fisher Linear Discriminant Analysis is described. Gait recognition technology, based on Hidden Markov Models has been explored, but those results are not included in this paper. Fusion approaches for combining the results of the biometrics would be the next step in realizing the secure portal

  10. Portal Hypertension

    MedlinePlus

    ... Chronic Hepatitis C Additional Content Medical News Portal Hypertension By Steven K. Herrine, MD NOTE: This is ... Hepatic Encephalopathy Jaundice in Adults Liver Failure Portal Hypertension Portal hypertension is abnormally high blood pressure in ...

  11. A Librarian's Perspective on Portals.

    ERIC Educational Resources Information Center

    Little, John R.

    2001-01-01

    Explains what Web portals are and discusses the benefits of a strategic alliance in portal building among campus information technology, libraries, and other campus groups. Suggests that by using robust channel capabilities, an enterprise portal can provide content from various parts of the university and promote resource discovery. (EV)

  12. Identification of radionuclides for the spectroscopic radiation portal monitor for pedestrian screening under a low signal-to-noise ratio condition

    NASA Astrophysics Data System (ADS)

    Min, Eungi; Ko, Mincheol; Lee, Hakjae; Kim, Yongkwon; Joung, Jinhun; Joo, Sung-Kwan; Lee, Kisung

    2014-09-01

    The spectroscopic radiation portal monitor (SPM) is widely used for homeland security. Many research groups are studying the radionuclide identification method which is one of the most important factors in the performance of the SPM using the large size of a thallium activated sodium iodide (NaI(Tl) detector. In this study, we developed the radionuclide identification method for the SPM for pedestrian screening using a single NaI(Tl) detector that is small in size (2 in.), which is much smaller than those in the existing studies under the low signal-to-noise-ratio (SNR) condition. From the anomalous radionuclide spectrum, the noise component was effectively reduced by the wavelet decomposition and the proposed background subtraction method, and the signal component was enhanced by the principal component analysis. Finally, peak locations which have been determined by the peak search algorithm with a valley check method were compared with a pre-calibrated and constructed radionuclide database. To verify the radiation identification performance of the proposed method, experiments with various kinds of sources (137Cs, 133Ba, 22Na, and 57Co) and different SNR values (from distances of 10-150 cm and for scan times of 1-5 s) were performed. Although the high-SNR condition was explored as well, most experiments were conducted under the low-SNR condition to verify the robustness and reproducibility of the proposed algorithm. The results showed that over 98.3% of the single radionuclide detection rate was achieved regardless of which radionuclides were used, up to 50 cm under the worst SNR condition (1 s of scan time) and up to 90 cm under the best SNR condition (5 s of scan time). Furthermore we achieved accurate identification of multiple radionuclides at 40 cm with only 1 s of scan time. The results show that the proposed algorithm is competitive with the commercial method and our radionuclide identification method can be successfully applied to the SPM for pedestrian

  13. Spectroscopic imaging technologies for online food safety and sanitation inspection

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Environmental Microbial and Food Safety Laboratory, ARS, USDA is one of the leading groups for the development of optoelectronic sensing technologies and methodologies for food quality, safety, and sanitation inspection. High throughput hyperspectral and multispectral imaging techniques use Ram...

  14. New and Expanded Spectroscopic Databases of the National Institute of Standards and Technology (NIST)

    NASA Astrophysics Data System (ADS)

    Wiese, Wolfgang L.

    2004-12-01

    Three atomic spectroscopic databases of the U.S. National Institute of Standards and Technology are reviewed. First, our principal spectroscopic database, the Atomic Spectra Database (ASD), is discussed, which will soon be put on the internet in a new, entirely redesigned and expanded version 3.0. This new edition will include several additional critical compilations that were recently completed at NIST. Furthermore, two new smaller specialized databases will be reviewed, - a handbook of basic atomic spectroscopic data and a tabulation of data for soft x-ray lines, tailored to the needs of x-ray space observatories. Finally, an overview of our plans for new critical data compilations during the next two-to-three years will be presented.

  15. Patient Portals as a Means of Information and Communication Technology Support to Patient-Centric Care Coordination – the Missing Evidence and the Challenges of Evaluation

    PubMed Central

    Georgiou, Andrew; Hyppönen, Hannele; Ammenwerth, Elske; de Keizer, Nicolette; Magrabi, Farah; Scott, Philip

    2015-01-01

    Summary Objectives To review the potential contribution of Information and Communication Technology (ICT) to enable patient-centric and coordinated care, and in particular to explore the role of patient portals as a developing ICT tool, to assess the available evidence, and to describe the evaluation challenges. Methods Reviews of IMIA, EFMI, and other initiatives, together with literature reviews. Results We present the progression from care coordination to care integration, and from patient-centric to person-centric approaches. We describe the different roles of ICT as an enabler of the effective presentation of information as and when needed. We focus on the patient’s role as a co-producer of health as well as the focus and purpose of care. We discuss the need for changing organisational processes as well as the current mixed evidence regarding patient portals as a logical tool, and the reasons for this dichotomy, together with the evaluation principles supported by theoretical frameworks so as to yield robust evidence. Conclusions There is expressed commitment to coordinated care and to putting the patient in the centre. However to achieve this, new interactive patient portals will be needed to enable peer communication by all stakeholders including patients and professionals. Few portals capable of this exist to date. The evaluation of these portals as enablers of system change, rather than as simple windows into electronic records, is at an early stage and novel evaluation approaches are needed. PMID:26123909

  16. A Portal of Educational Resources: Providing Evidence for Matching Pedagogy with Technology

    ERIC Educational Resources Information Center

    Di Blas, Nicoletta; Fiore, Alessandro; Mainetti, Luca; Vergallo, Roberto; Paolini, Paolo

    2014-01-01

    The TPACK (Technology, Pedagogy and Content Knowledge) model presents the three types of knowledge that are necessary to implement a successful technology-based educational activity. It highlights how the intersections between TPK (Technological Pedagogical Knowledge), PCK (Pedagogical Content Knowledge) and TCK (Technological Content Knowledge)…

  17. Health literacy and patient portals.

    PubMed

    Gu, Yulong; Orr, Martin; Warren, Jim

    2015-06-01

    Health literacy has been described as the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions. Improving health literacy may serve to promote concordance with therapy, engage patients in their own health care, and improve health outcomes. Patient portal technology aims at enabling patients and families to have easy access to key information in their own medical records and to communicate with their health care providers electronically. However, there is a gap in our understanding of how portals will improve patient outcome. The authors believe patient portal technology presents an opportunity to improve patient concordance with prescribed therapy, if adequate support is provided to equip patients (and family/carers) with the knowledge needed to utilise the health information available via the portals. Research is needed to understand what a health consumer will use patient portals for and how to support a user to realise the technology's potential. PMID:26125067

  18. Implementation of Certified EHR, Patient Portal, and "Direct" Messaging Technology in a Radiology Environment Enhances Communication of Radiology Results to Both Referring Physicians and Patients.

    PubMed

    Reicher, Joshua Jay; Reicher, Murray Aaron

    2016-06-01

    Since 2009, the Federal government distributed over $29 billion to providers who were adopting compliant electronic health record (EHR) technology. With a focus on radiology, we explore how EHR technology impacts interoperability with referring clinicians' EHRs and patient engagement. We also discuss the high-level details of contributing supporting frameworks, specifically Direct messaging and health information service provider (HISP) technology. We characterized Direct messaging, a secure e-mail-like protocol built to allow exchange of encrypted health information online, and the new supporting HISP infrastructure. Statistics related to both the testing and active use of this framework were obtained from DirectTrust.org, an organization whose framework supports Direct messaging use by healthcare organizations. To evaluate patient engagement, we obtained usage data from a radiology-centric patient portal between 2014 and 2015, which in some cases included access to radiology reports. Statistics from 2013 to 2015 showed a rise in issued secure Direct addresses from 8724 to 752,496; a rise in the number of participating healthcare organizations from 667 to 39,751; and a rise in the secure messages sent from 122,842 to 27,316,438. Regarding patient engagement, an average of 234,679 patients per month were provided portal access, with 86,400 patients per month given access to radiology reports. Availability of radiology reports online was strongly associated with increased system usage, with a likelihood ratio of 2.63. The use of certified EHR technology and Direct messaging in the practice of radiology allows for the communication of patient information and radiology results with referring clinicians and increases patient use of patient portal technology, supporting bidirectional radiologist-patient communication. PMID:26588906

  19. The NUCLEONICA Nuclear Science Portal

    SciTech Connect

    Magill, Joseph; Dreher, Raymond

    2009-08-19

    NUCLEONICA (www.nucleonica.net) is a new nuclear science web portal which provides a customisable, integrated environment and collaboration platform using the latest internet 'Web 2.0' technology. NUCLEONICA is aimed at professionals, academics and students working in nuclear power, health physics and radiation protection, nuclear and radio-chemistry, and astrophysics. A unique feature of the portal is the wide range of user friendly web-based nuclear science applications. The portal is also ideal for education and training purposes and as a knowledge management platform to preserve nuclear knowledge built up over many decades.

  20. Developing Interoperable Air Quality Community Portals

    NASA Astrophysics Data System (ADS)

    Falke, S. R.; Husar, R. B.; Yang, C. P.; Robinson, E. M.; Fialkowski, W. E.

    2009-04-01

    Web portals are intended to provide consolidated discovery, filtering and aggregation of content from multiple, distributed web sources targeted at particular user communities. This paper presents a standards-based information architectural approach to developing portals aimed at air quality community collaboration in data access and analysis. An important characteristic of the approach is to advance beyond the present stand-alone design of most portals to achieve interoperability with other portals and information sources. We show how using metadata standards, web services, RSS feeds and other Web 2.0 technologies, such as Yahoo! Pipes and del.icio.us, helps increase interoperability among portals. The approach is illustrated within the context of the GEOSS Architecture Implementation Pilot where an air quality community portal is being developed to provide a user interface between the portals and clearinghouse of the GEOSS Common Infrastructure and the air quality community catalog of metadata and data services.

  1. Application of open source standards and technologies in the http://climate4impact.eu/ portal

    NASA Astrophysics Data System (ADS)

    Plieger, Maarten; Som de Cerff, Wim; Pagé, Christian; Tatarinova, Natalia

    2015-04-01

    This presentation will demonstrate how to calculate and visualize the climate indice SU (number of summer days) on the climate4impact portal. The following topics will be covered during the demonstration: - Security: Login using OpenID for access to the Earth System Grid Fedeation (ESGF) data nodes. The ESGF works in conjunction with several external websites and systems. The climate4impact portal uses X509 based short lived credentials, generated on behalf of the user with a MyProxy service. Single Sign-on (SSO) is used to make these websites and systems work together. - Discovery: Facetted search based on e.g. variable name, model and institute using the ESGF search services. A catalog browser allows for browsing through CMIP5 and any other climate model data catalogues (e.g. ESSENCE, EOBS, UNIDATA). - Processing using Web Processing Services (WPS): Transform data, subset, export into other formats, and perform climate indices calculations using Web Processing Services implemented by PyWPS, based on NCAR NCPP OpenClimateGIS and IS-ENES2 ICCLIM. - Visualization using Web Map Services (WMS): Visualize data from ESGF data nodes using ADAGUC Web Map Services. The aim of climate4impact is to enhance the use of Climate Research Data and to enhance the interaction with climate effect/impact communities. The portal is based on 21 impact use cases from 5 different European countries, and is evaluated by a user panel consisting of use case owners. It has been developed within the European projects IS-ENES and IS-ENES2 for more than 5 years, and its development currently continues within IS-ENES2 and CLIPC. As the climate impact community is very broad, the focus is mainly on the scientific impact community. This work has resulted in the ENES portal interface for climate impact communities and can be visited at http://climate4impact.eu/ The current main objectives for climate4impact can be summarized in two objectives. The first one is to work on a web interface which

  2. Using information communication technologies to increase the institutional capacity of local health organisations in Africa: a case study of the Kenya Civil Society Portal for Health

    PubMed Central

    Juma, Charles; Sundsmo, Aaron; Maket, Boniface; Powell, Richard; Aluoch, Gilbert

    2015-01-01

    Introduction Achieving the healthcare components of the United Nations’ Millennium Development Goals is significantly premised on effective service delivery by civil society organisations (CSOs). However, many CSOs across Africalack the necessary capacity to perform this role robustly. This paper reports on an evaluation of the use, and perceived impact, of aknowledge management tool upon institutional strengthening among CSOs working in Kenya's health sector. Methods Three methods were used: analytics data; user satisfaction surveys; and a furtherkey informant survey. Results Satisfaction with the portal was consistently high, with 99% finding the quality and relevance of the content very good or good for institutional strengthening standards, governance, and planning and resource mobilisation. Critical facilitators to the success of knowledge management for CSO institutional strengthening were identified as people/culture (developed resources and organisational narratives) and technology (easily accessible, enabling information exchange, tools/resources available, access to consultants/partners). Critical barriers were identified as people/culture (database limitations, materials limitations, and lack of active users), and process (limited access, limited interactions, and limited approval process). Conclusion This pilot study demonstrated the perceived utility of a web-based knowledge management portal among developing nations’ CSOs, with widespread satisfaction across multiple domains, which increased over time. Providing increased opportunities for collective mutual learning, promoting a culture of data use for decision making, and encouraging all health organisations to be learning institutions should be a priority for those interested in promoting sustainable long-term solutions for Africa. PMID:26401217

  3. IDL Grid Web Portal

    NASA Astrophysics Data System (ADS)

    Massimino, P.; Costa, A.

    2008-08-01

    Image Data Language is a software for data analysis, visualization and cross-platform application development. The potentiality of IDL is well-known in the academic scientific world, especially in the astronomical environment where thousands of procedures are developed by using IDL. The typical use of IDL is the interactive mode but it is also possible to run IDL programs that do not require any interaction with the user, submitting them in batch or background modality. Through the interactive mode the user immediately receives images or other data produced in the running phase of the program; in batch or background mode, the user will have to wait for the end of the program, sometime for many hours or days to obtain images or data that IDL produced as output: in fact in Grid environment it is possible to access to or retrieve data only after completion of the program. The work that we present gives flexibility to IDL procedures submitted to the Grid computer infrastructure. For this purpose we have developed an IDL Grid Web Portal to allow the user to access the Grid and to submit IDL programs granting a full job control and the access to images and data generated during the running phase, without waiting for their completion. We have used the PHP technology and we have given the same level of security that Grid normally offers to its users. In this way, when the user notices that the intermediate program results are not those expected, he can stop the job, change the parameters to better satisfy the computational algorithm and resubmit the program, without consuming the CPU time and other Grid resources. The IDL Grid Web Portal allows you to obtain IDL generated images, graphics and data tables by using a normal browser. All conversations from the user and the Grid resources occur via Web, as well as authentication phases. The IDL user has not to change the program source much because the Portal will automatically introduce the appropriate modification before

  4. Portal radiation monitor

    DOEpatents

    Kruse, L.W.

    1982-03-23

    A portal radiation monitor combines .1% FAR with high sensitivity to special nuclear material. The monitor utilizes pulse shape discrimination, dynamic compression of the photomultiplier output and scintillators sized to maintain efficiency over the entire portal area.

  5. Cirrhosis and Portal Hypertension

    MedlinePlus

    MENU Return to Web version Cirrhosis and Portal Hypertension Overview What is cirrhosis? In people who have ... lead to coma and death. What is portal hypertension? Normally, blood is carried to the liver by ...

  6. Portal radiation monitor

    DOEpatents

    Kruse, Lyle W.

    1985-01-01

    A portal radiation monitor combines 0.1% FAR with high sensitivity to special nuclear material. The monitor utilizes pulse shape discrimination, dynamic compression of the photomultiplier output and scintillators sized to maintain efficiency over the entire portal area.

  7. A Community of Practice: Web Portals and Faculty Development.

    ERIC Educational Resources Information Center

    Carlson, Patricia A.

    2002-01-01

    Describes a Web portal constructed by Rose-Hulman Institute of Technology dedicated to improving middle school science, mathematics, and technology instruction. The portal emulates emerging corporate practices of knowledge management and process reinvention through information technology, and offers middle school teachers across Indiana a…

  8. The Advent of Portals.

    ERIC Educational Resources Information Center

    Jackson, Mary E.

    2002-01-01

    Explains portals as tools that gather a variety of electronic information resources, including local library resources, into a single Web page. Highlights include cross-database searching; integration with university portals and course management software; the ARL (Association of Research Libraries) Scholars Portal Initiative; and selected vendors…

  9. Evaluating Open Source Portals

    ERIC Educational Resources Information Center

    Goh, Dion; Luyt, Brendan; Chua, Alton; Yee, See-Yong; Poh, Kia-Ngoh; Ng, How-Yeu

    2008-01-01

    Portals have become indispensable for organizations of all types trying to establish themselves on the Web. Unfortunately, there have only been a few evaluative studies of portal software and even fewer of open source portal software. This study aims to add to the available literature in this important area by proposing and testing a checklist for…

  10. Noncirrhotic Portal Hypertension

    PubMed Central

    Rajekar, Harshal; Vasishta, Rakesh K; Chawla, Yogesh K; Dhiman, Radha K

    2011-01-01

    Portal hypertension is characterized by an increase in portal pressure (> 10 mmHg) and could be a result of cirrhosis of the liver or of noncirrhotic diseases. When portal hypertension occurs in the absence of liver cirrhosis, noncirrhotic portal hypertension (NCPH) must be considered. The prognosis of this disease is much better than that of cirrhosis. Noncirrhotic diseases are the common cause of portal hypertension in developing countries, especially in Asia. NCPH is a heterogeneous group of diseases that is due to intrahepatic or extrahepatic etiologies. In general, the lesions in NCPH are vascular in nature and can be classified based on the site of resistance to blood flow. In most cases, these disorders can be explained by endothelial cell lesions, intimal thickening, thrombotic obliterations, or scarring of the intrahepatic portal or hepatic venous circulation. Many different conditions can determine NCPH through the association of these various lesions in various degrees. Many clinical manifestations of NCPH result from the secondary effects of portal hypertension. Patients with NCPH present with upper gastrointestinal bleeding, splenomegaly, ascites after gastrointestinal bleeding, features of hypersplenism, growth retardation, and jaundice due to portal hypertensive biliopathy. Other sequelae include hyperdynamic circulation, pulmonary complications, and other effects of portosystemic collateral circulation like portosystemic encephalopathy. At present, pharmacologic and endoscopic treatments are the treatments of choice for portal hypertension. The therapy of all disorders causing NCPH involves the reduction of portal pressure by pharmacotherapy or portosystemic shunting, apart from prevention and treatment of complications of portal hypertension. PMID:25755321

  11. Endoscopic Management of Portal Hypertension

    PubMed Central

    Al-Busafi, Said A.; Ghali, Peter; Wong, Philip; Deschenes, Marc

    2012-01-01

    Cirrhosis is the leading cause of portal hypertension worldwide, with the development of bleeding gastroesophageal varices being one of the most life-threatening consequences. Endoscopy plays an indispensible role in the diagnosis, staging, and prophylactic or active management of varices. With the expected future refinements in endoscopic technology, capsule endoscopy may one day replace traditional gastroscopy as a diagnostic modality, whereas endoscopic ultrasound may more precisely guide interventional therapy for gastric varices. PMID:22830037

  12. Cross-Cultural Dimensions of Internet Portals.

    ERIC Educational Resources Information Center

    Zahir, Sajjad; Dobing, Brian; Hunter, M. Gordon

    2002-01-01

    Discussion of cultural influences on new technologies focuses on an analysis of full-service national Web portals from different countries that investigated whether the adoption of new technologies resulted in cultural convergence or divergence. Results showed differences in appearance and features offered that can be attributed to cultural…

  13. Portal Vein Thrombosis

    PubMed Central

    Mallet, Thierry; Soltys, Remigiusz; Loarte, Pablo

    2015-01-01

    Portal vein thrombosis (PVT) is the blockage or narrowing of the portal vein by a thrombus. It is relatively rare and has been linked with the presence of an underlying liver disease or prothrombotic disorders. We present a case of a young male who presented with vague abdominal symptoms for approximately one week. Imaging revealed the presence of multiple nonocclusive thrombi involving the right portal vein, the splenic vein, and the left renal vein, as well as complete occlusion of the left portal vein and the superior mesenteric vein. We discuss pathogenesis, clinical presentation, and management of both acute and chronic thrombosis. The presence of PVT should be considered as a clue for prothrombotic disorders, liver disease, and other local and general factors that must be carefully investigated. It is hoped that this case report will help increase awareness of the complexity associated with portal vein thrombosis among the medical community. PMID:25802795

  14. The CEOS Water Portal

    NASA Astrophysics Data System (ADS)

    Miura, Satoko; Sekioka, Shinichi; Kuroiwa, Kaori; Kudo, Yoshiyuki; Koide, Michihiro

    2014-05-01

    The CEOS Water is a one of the DIAS (Data Integration and Analysis System, http://www.editoria.u-tokyo.ac.jp/projects/dias/?locale=en_US) data distributed systems. The CEOS Water Portal system is distributed in the sense that, while the portal system is located in Tokyo, the data is located in archive centers which are globally distributed. For example, some in-situ data is archived at the National Center for Atmospheric Research (NCAR) Earth Observing Laboratory in Boulder, Colorado, USA. The NWP station time series and global gridded model output data is archived at the Max Planck Institute for Meteorology (MPIM) in cooperation with the World Data Centerfor Climate in Hamburg, Germany. Part of satellite data is archived at DIAS storage at the University of Tokyo, Japan. This portal does not store data. Instead, according to requests made by users on the web page, it retrieves data from distributed data centers on-the-fly and lets them download and see rendered images/plots. Considering the popularity among water related data centers, OpenDAP protocol is mainly being used between this portal and most of data centers. And this portal also is connected to a kind of data brokering system, which is already connected to multiple data centers. For this interface, OpenSearch protocol is being used. The CEOS Water Portal intends to extend its users to include decision makers and officers like river administrators by facilitating a feedback loop. One example of data and information flow centered on the CEOS Water Portal is shown below. (1)Scientists get various data needed for Model Calculation (WEB-DHM, for example) via the portal. (2)Scientists use Model output data and do analysis. (3)Scientists register their use cases into the portal. (4)Decision makers and officers can refer and acquire use cases and data easily. Users can access the CEOS Water Portal system at http://waterportal.ceos.org/.

  15. Portal vein thrombosis.

    PubMed

    Chawla, Yogesh K; Bodh, Vijay

    2015-03-01

    Portal vein thrombosis is an important cause of portal hypertension. PVT occurs in association with cirrhosis or as a result of malignant invasion by hepatocellular carcinoma or even in the absence of associated liver disease. With the current research into its genesis, majority now have an underlying prothrombotic state detectable. Endothelial activation and stagnant portal blood flow also contribute to formation of the thrombus. Acute non-cirrhotic PVT, chronic PVT (EHPVO), and portal vein thrombosis in cirrhosis are the three main variants of portal vein thrombosis with varying etiological factors and variability in presentation and management. Procoagulant state should be actively investigated. Anticoagulation is the mainstay of therapy for acute non-cirrhotic PVT, with supporting evidence for its use in cirrhotic population as well. Chronic PVT (EHPVO) on the other hand requires the management of portal hypertension as such and with role for anticoagulation in the setting of underlying prothrombotic state, however data is awaited in those with no underlying prothrombotic states. TIPS and liver transplant may be feasible even in the setting of PVT however proper selection of candidates and type of surgery is warranted. Thrombolysis and thrombectomy have some role. TARE is a new modality for management of HCC with portal vein invasion. PMID:25941431

  16. Portal Vein Thrombosis

    PubMed Central

    Chawla, Yogesh K.; Bodh, Vijay

    2015-01-01

    Portal vein thrombosis is an important cause of portal hypertension. PVT occurs in association with cirrhosis or as a result of malignant invasion by hepatocellular carcinoma or even in the absence of associated liver disease. With the current research into its genesis, majority now have an underlying prothrombotic state detectable. Endothelial activation and stagnant portal blood flow also contribute to formation of the thrombus. Acute non-cirrhotic PVT, chronic PVT (EHPVO), and portal vein thrombosis in cirrhosis are the three main variants of portal vein thrombosis with varying etiological factors and variability in presentation and management. Procoagulant state should be actively investigated. Anticoagulation is the mainstay of therapy for acute non-cirrhotic PVT, with supporting evidence for its use in cirrhotic population as well. Chronic PVT (EHPVO) on the other hand requires the management of portal hypertension as such and with role for anticoagulation in the setting of underlying prothrombotic state, however data is awaited in those with no underlying prothrombotic states. TIPS and liver transplant may be feasible even in the setting of PVT however proper selection of candidates and type of surgery is warranted. Thrombolysis and thrombectomy have some role. TARE is a new modality for management of HCC with portal vein invasion. PMID:25941431

  17. Monte Carlo portal dosimetry

    SciTech Connect

    Chin, P.W. . E-mail: mary.chin@physics.org

    2005-10-15

    This project developed a solution for verifying external photon beam radiotherapy. The solution is based on a calibration chain for deriving portal dose maps from acquired portal images, and a calculation framework for predicting portal dose maps. Quantitative comparison between acquired and predicted portal dose maps accomplishes both geometric (patient positioning with respect to the beam) and dosimetric (two-dimensional fluence distribution of the beam) verifications. A disagreement would indicate that beam delivery had not been according to plan. The solution addresses the clinical need for verifying radiotherapy both pretreatment (without the patient in the beam) and on treatment (with the patient in the beam). Medical linear accelerators mounted with electronic portal imaging devices (EPIDs) were used to acquire portal images. Two types of EPIDs were investigated: the amorphous silicon (a-Si) and the scanning liquid ion chamber (SLIC). The EGSnrc family of Monte Carlo codes were used to predict portal dose maps by computer simulation of radiation transport in the beam-phantom-EPID configuration. Monte Carlo simulations have been implemented on several levels of high throughput computing (HTC), including the grid, to reduce computation time. The solution has been tested across the entire clinical range of gantry angle, beam size (5 cmx5 cm to 20 cmx20 cm), and beam-patient and patient-EPID separations (4 to 38 cm). In these tests of known beam-phantom-EPID configurations, agreement between acquired and predicted portal dose profiles was consistently within 2% of the central axis value. This Monte Carlo portal dosimetry solution therefore achieved combined versatility, accuracy, and speed not readily achievable by other techniques.

  18. Portal to the Future

    NASA Astrophysics Data System (ADS)

    Gates, Evalyn

    2011-04-01

    Museums are a portal connecting us to a deeper understanding of the world in which we live, from our own backyards to the most distant galaxies; an access point to the incredible discoveries we have made about the natural world and a flashpoint for inspiring the next generation of explorers. The Cleveland Museum of Natural History is poised to redefine what a natural history museum can be, offering visitors an opportunity to travel through space and time to explore the origins of our planet, follow the evolution of life on Earth and project into -- and plan for -- the future. The Museum will launch visitors into the future this summer via SmartHome Cleveland -- an extremely energy-efficient "passive house" that will demonstrate the future of green building technology. This unique exhibit is part of a special series of exhibits, programs and workshops on sustainability, including a major exhibit on Climate Change, which will be featured at the Museum this summer and fall.

  19. 77 FR 67738 - Proposed Information Collection (eBenefits Portal) Activity: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-13

    ... AFFAIRS Proposed Information Collection (eBenefits Portal) Activity: Comment Request AGENCY: Office of... information needed to access the eBenefits portal. DATES: Written comments and recommendations on the proposed... forms of information technology. Title: eBenefits Portal. OMB Control Number: 2900-0737. Type of...

  20. IR spectroscopic investigations of amoxicillin trihydrate, included in the technological models sirup granules in ethylcellulose

    NASA Astrophysics Data System (ADS)

    Gasheva, L. M.; Kalinkova, G.; Minkov, E.; Krestev, V.

    1984-03-01

    Employing IR spectroscopy some technological models of amoxicillin trihydrate, included in ethyl-, methyl-, carboxymethyl- and methylhydroxyethyl-cellulose have been studied. Interactions were established only between amoxicillin trihydrate and ethylcellulose. The IR absorption spectra suggest a H-bonded antibiotic with hydroxyl groups in the ethylcellulose molecule. The IR spectral differences observed are not due to polymorphic transformation; this was proved by X-ray powder diffraction.

  1. Space Development Grid Portal

    NASA Technical Reports Server (NTRS)

    Vaziri, Arsi

    2004-01-01

    This viewgraph presentation provides information on the development of a portal to provide secure and distributed grid computing for Payload Operations Integrated Center and Mission Control Center ground services.

  2. Differences in Access to and Preferences for Using Patient Portals and Other eHealth Technologies Based on Race, Ethnicity, and Age: A Database and Survey Study of Seniors in a Large Health Plan

    PubMed Central

    Hornbrook, Mark C

    2016-01-01

    portal to send messages, view lab test results, or order prescription refills. Across all age groups, non-Hispanic whites and Chinese seniors were significantly more likely than black, Latino, and Filipino seniors to be registered and to have performed these actions. The survey found that black, Latino, and Filipino seniors and those 75 years old and older were significantly less likely to own digital devices (eg, computers, smartphones), use the Internet and email, and be able and willing to use digital technology to perform health care-related tasks, including obtaining health information, than non-Hispanic whites, Chinese, and younger seniors (aged 65-69), respectively. The preference for using non-digital modalities persisted even among Internet users. Conclusions Health plans, government agencies, and other organizations that serve diverse groups of seniors should include social determinants such as race/ethnicity and age when monitoring trends in eHealth to ensure that eHealth disparities do not induce greater health status and health care disparities between more privileged and less privileged groups. PMID:26944212

  3. Unifying access to services: ESO's user portal

    NASA Astrophysics Data System (ADS)

    Chavan, A. M.; Tacconi-Garman, L. E.; Peron, M.; Sogni, F.; Canavan, T.; Nass, P.

    2006-06-01

    The European Southern Observatory (ESO) is in the process of creating a central access point for all services offered to its user community via the Web. That gateway, called the User Portal, will provide registered users with a personalized set of service access points, the actual set depending on each user's privileges. Correspondence between users and ESO will take place by way of "profiles", that is, contact information. Each user may have several active profiles, so that an investigator may choose, for instance, whether their data should be delivered to their own address or to a collaborator. To application developers, the portal will offer authentication and authorization services, either via database queries or an LDAP server. The User Portal is being developed as a Web application using Java-based technology, including servlets and JSPs.

  4. Outsourcing the Portal: Another Branch in the Decision Tree.

    ERIC Educational Resources Information Center

    McMahon, Tim

    2000-01-01

    Discussion of the management of information resources in organizations focuses on the use of portal technologies to update intranet capabilities. Considers application outsourcing decisions, reviews benefits (including reducing costs) as well as concerns, and describes application service providers (ASPs). (LRW)

  5. Building Your Campus Portal: Advice from the Field.

    ERIC Educational Resources Information Center

    Krebs, Arlene

    2001-01-01

    Discusses portal technology in higher education, including planning, design, technical, and financial issues. Highlights include determining the customers; marketing possibilities for the university; ownership issues; data design; effective cost structuring; security issues; adaptability; content; and customer input and feedback. (LRW)

  6. 8. EAST PORTAL AND DECK VIEW, FROM EAST, SHOWING PORTAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. EAST PORTAL AND DECK VIEW, FROM EAST, SHOWING PORTAL CONFIGURATION AND LATERAL BRACING, STEEL MESH FLOOR, METAL RAILINGS, AND PORTION OF EAST APPROACH - Glendale Road Bridge, Spanning Deep Creek Lake on Glendale Road, McHenry, Garrett County, MD

  7. 7. WEST PORTAL AND DECK VIEW, FROM WEST, SHOWING PORTAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. WEST PORTAL AND DECK VIEW, FROM WEST, SHOWING PORTAL CONFIGURATION AND LATERAL BRACING, STEEL MESH FLOOR, AND METAL RAILINGS - Glendale Road Bridge, Spanning Deep Creek Lake on Glendale Road, McHenry, Garrett County, MD

  8. Radioisotopic flow scanning for portal blood flow and portal hypertension

    SciTech Connect

    Hesdorffer, C.S.; Bezwoda, W.R.; Danilewitz, M.D.; Esser, J.D.; Tobias, M.

    1987-08-01

    The use of a simple, noninvasive, isotope scanning technique for the determination of relative portal blood flow and detection of portal hypertension is described. Using this technique the presence of portal hypertension was demonstrated in seven of nine patients known to have elevated portal venous pressure. By contrast, esophageal varices were demonstrated in only five of these patients, illustrating the potential value of the method. Furthermore, this technique has been adapted to the study of portal blood flow in patients with myeloproliferative disorders with splenomegaly but without disturbances in hepatic architecture. Results demonstrate that the high relative splenic flow resulting from the presence of splenomegaly may in turn be associated with elevated relative portal blood flow and portal hypertension. The theoretic reasons for the development of flow-related portal hypertension and its relationship to splenic blood flow are discussed.

  9. Perspective view of south portal. Note how portal angles about ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Perspective view of south portal. Note how portal angles about 5' forward over the approach. - Red Oak Creek Bridge, Spanning (Big) Red Oak Creek, Huel Brown Road (Covered Bridge Road), Woodbury, Meriwether County, GA

  10. Elevation, west portal. Sign on portal reads Watson Mill Bridge, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Elevation, west portal. Sign on portal reads Watson Mill Bridge, est. 1885. - Watson Mill Bridge, Spanning South Fork Broad River, Watson Mill Road, Watson Mill Bridge State Park, Comer, Madison County, GA

  11. Pregnancy with Portal Hypertension

    PubMed Central

    Aggarwal, Neelam; Negi, Neha; Aggarwal, Aakash; Bodh, Vijay; Dhiman, Radha K.

    2014-01-01

    Even though pregnancy is rare with cirrhosis and advanced liver disease, but it may co-exist in the setting of non-cirrhotic portal hypertension as liver function is preserved but whenever encountered together is a complex clinical dilemma. Pregnancy in a patient with portal hypertension presents a special challenge to the obstetrician as so-called physiological hemodynamic changes associated with pregnancy, needed for meeting demands of the growing fetus, worsen the portal hypertension thereby putting mother at risk of potentially life-threatening complications like variceal hemorrhage. Risks of variceal bleed and hepatic decompensation increase many fold during pregnancy. Optimal management revolves round managing the portal hypertension and its complications. Thus management of such cases requires multi-speciality approach involving obstetricians experienced in dealing with high risk cases, hepatologists, anesthetists and neonatologists. With advancement in medical field, pregnancy is not contra-indicated in these women, as was previously believed. This article focuses on the different aspects of pregnancy with portal hypertension with special emphasis on specific cause wise treatment options to decrease the variceal bleed and hepatic decompensation. Based on extensive review of literature, management from pre-conceptional period to postpartum is outlined in order to have optimal maternal and perinatal outcomes. PMID:25755552

  12. Synteny Portal: a web-based application portal for synteny block analysis.

    PubMed

    Lee, Jongin; Hong, Woon-Young; Cho, Minah; Sim, Mikang; Lee, Daehwan; Ko, Younhee; Kim, Jaebum

    2016-07-01

    Recent advances in next-generation sequencing technologies and genome assembly algorithms have enabled the accumulation of a huge volume of genome sequences from various species. This has provided new opportunities for large-scale comparative genomics studies. Identifying and utilizing synteny blocks, which are genomic regions conserved among multiple species, is key to understanding genomic architecture and the evolutionary history of genomes. However, the construction and visualization of such synteny blocks from multiple species are very challenging, especially for biologists with a lack of computational skills. Here, we present Synteny Portal, a versatile web-based application portal for constructing, visualizing and browsing synteny blocks. With Synteny Portal, users can easily (i) construct synteny blocks among multiple species by using prebuilt alignments in the UCSC genome browser database, (ii) visualize and download syntenic relationships as high-quality images, (iii) browse synteny blocks with genetic information and (iv) download the details of synteny blocks to be used as input for downstream synteny-based analyses, all in an intuitive and easy-to-use web-based interface. We believe that Synteny Portal will serve as a highly valuable tool that will enable biologists to easily perform comparative genomics studies by compensating limitations of existing tools. Synteny Portal is freely available at http://bioinfo.konkuk.ac.kr/synteny_portal. PMID:27154270

  13. Synteny Portal: a web-based application portal for synteny block analysis

    PubMed Central

    Lee, Jongin; Hong, Woon-young; Cho, Minah; Sim, Mikang; Lee, Daehwan; Ko, Younhee; Kim, Jaebum

    2016-01-01

    Recent advances in next-generation sequencing technologies and genome assembly algorithms have enabled the accumulation of a huge volume of genome sequences from various species. This has provided new opportunities for large-scale comparative genomics studies. Identifying and utilizing synteny blocks, which are genomic regions conserved among multiple species, is key to understanding genomic architecture and the evolutionary history of genomes. However, the construction and visualization of such synteny blocks from multiple species are very challenging, especially for biologists with a lack of computational skills. Here, we present Synteny Portal, a versatile web-based application portal for constructing, visualizing and browsing synteny blocks. With Synteny Portal, users can easily (i) construct synteny blocks among multiple species by using prebuilt alignments in the UCSC genome browser database, (ii) visualize and download syntenic relationships as high-quality images, (iii) browse synteny blocks with genetic information and (iv) download the details of synteny blocks to be used as input for downstream synteny-based analyses, all in an intuitive and easy-to-use web-based interface. We believe that Synteny Portal will serve as a highly valuable tool that will enable biologists to easily perform comparative genomics studies by compensating limitations of existing tools. Synteny Portal is freely available at http://bioinfo.konkuk.ac.kr/synteny_portal. PMID:27154270

  14. Application of the smart portal in transportation

    NASA Astrophysics Data System (ADS)

    Kercel, Stephen W.; Baylor, Vivian M.; Dress, William B.; Hickerson, Tim W.; Jatko, William B.; Labaj, Leo E.; Muhs, Jeffrey D.; Pack, Richard M.

    1997-02-01

    Under a program sponsored by the Department of Energy, the Oak Ridge complex is developing a `Portal-of-the-Future', or `smart portal.' This is a security portal for vehicular traffic which is intended to quickly detect explosives, hidden passengers, etc. It uses several technologies, including microwaves, weigh-in-motion, digital image processing, and electroacoustic wavelet-based heartbeat detection. A novel component of particular interest is the Enclosed Space Detection System (ESDS), which detects the presence of persons hiding in a vehicle. The system operates by detecting the presence of a human ballistocardiographic signature. Each time the heart beats, it generates a small but measurable shock wave that propagates through the body. The wave, whose graph is called a ballistocardiogram, is the mechanical analog of the electrocardiograms, which is routinely used for medical diagnosis. The wave is, in turn, coupled to any surface or object with which the body is in contact. If the body is located in an enclosed space, this will result in a measurable deflection of the surface of the enclosure. Independent testing has shown ESDS to be highly reliable. The technologies used in the smart portal operate in real time and allow vehicles to be checked through the portal in much less time than would be required for human inspection. Although not originally developed for commercial transportation, the smart portal has the potential to solve several transportation problems. It could relieve congestion at international highway border crossings by reducing the time required to inspect each vehicle while increasing the level of security. It can reduce highway congestion at the entrance of secure facilities such as prisons. Also, it could provide security at intermodal transfer points, such as airport parking lots and car ferry terminals.

  15. Application of the smart portal in transportation

    SciTech Connect

    Kercel, S.W.; Baylor, V.M.; Dress, W.B.; Hickerson, T.W.; Jatko, W.B.; Labaj, L.E.; Muhs, J.D.; Pack, R.M.

    1996-12-31

    Under a program sponsored by the Department of Energy, the Oak Ridge complex is developed a ``Portal-of-the-Future``, or ``smart portal``. This is a security portal for vehicular traffic which is intended to quickly detect explosives, hidden passengers, etc. It uses several technologies, including microwaves, weigh-in-motion, digital image processing, and electroacoustic wavelet-based heartbeat detection. A novel component of particular interest is the Enclosed Space Detection System (ESDS), which detects the presence of persons hiding in a vehicle. The system operates by detecting the presence of a human ballistocardiographic signature. Each time the heart beats, it generates a small but measurable shock wave that propagates through the body. The wave, whose graph is called a ballistocardiogram, is the mechanical analog of the electrocardiogram, which is routinely used for medical diagnosis. The wave is, in turn, coupled to any surface or object with which the body is in contact. If the body is located in an enclosed space, this will result in a measurable deflection of the surface of the enclosure. Independent testing has shown ESDS to be highly reliable. The technologies used in the smart portal operate in real time and allow vehicles to be checked through the portal in much less time than would be required for human inspection. Although not originally developed for commercial transportation, the smart portal has the potential to solve several transportation problems. It could relieve congestion at international highway border crossings by reducing the time required to inspect each vehicle while increasing the level of security. It can reduce highway congestion at the entrance of secure facilities such as prisons. Also, it could provide security at intermodal transfer points, such as airport parking lots and car ferry terminals.

  16. [Portal vein thrombosis].

    PubMed

    Seijo-Ríos, Susana; García-Pagán, Juan Carlos

    2010-03-01

    Thrombosis of the splenoportal axis not associated with liver cirrhosis or tumoral disease is the second cause of portal hypertension in the western world. In up to 60% of cases, an underlying systemic prothrombotic disorder can be identified as an etiological factor. One third of cases are caused by local factors and the coexistence of several entities is not unusual. Therefore, an etiologic diagnosis is essential in these patients. Early anticoagulation therapy in the acute phase of thrombosis of the splenoportal axis significantly affects the probability of recanalization and consequently the prognosis of these patients. In the chronic phase of splenoportal thrombosis (or portal cavernoma), the symptoms are caused by the complications of established portal hypertension. To date, anticoagulation therapy is limited to patients in whom an underlying prothrombotic disorder has been demonstrated. PMID:19733938

  17. Target detection portal

    DOEpatents

    Linker, Kevin L.; Brusseau, Charles A.

    2002-01-01

    A portal apparatus for screening persons or objects for the presence of trace amounts of target substances such as explosives, narcotics, radioactive materials, and certain chemical materials. The portal apparatus can have a one-sided exhaust for an exhaust stream, an interior wall configuration with a concave-shape across a horizontal cross-section for each of two facing sides to result in improved airflow and reduced washout relative to a configuration with substantially flat parallel sides; air curtains to reduce washout; ionizing sprays to collect particles bound by static forces, as well as gas jet nozzles to dislodge particles bound by adhesion to the screened person or object. The portal apparatus can be included in a detection system with a preconcentrator and a detector.

  18. The NOAO NVO Portal: Client-Side VO

    NASA Astrophysics Data System (ADS)

    Gasson, D.; Fuentes, E.; Miller, C. J.

    2007-10-01

    The NOAO National Virtual Observatory (NVO) portal is a recently deployed web application for one-stop discovery, analysis, and access to VO-compliant imaging data and services. The NOAO NVO portal utilizes Simple Image Access Protocol (SIAP) services provided by some astronomical archives. The portal also utilizes a number of SOAP-based VO web services (WESIX, Sesame, etc). We discuss the design decisions and technology choices that were made in the NOAO NVO portal code to facilitate the use of IVOA standards and VO data/services. This includes a new Virtual Observatory library written for Ruby: an interpreted scripting language for quick and easy object-oriented programming. We provide an overview of VORuby and how it is utilized in the NOAO NVO Portal.

  19. Health Literacy, Education Levels, and Patient Portal Usage During Hospitalizations

    PubMed Central

    Davis, Sharon E.; Osborn, Chandra Y.; Kripalani, Sunil; Goggins, Kathryn M.; Jackson, Gretchen Purcell

    2015-01-01

    Patient portal adoption has rapidly increased, and portal usage has been associated with patients’ sociodemographics, health literacy, and education. Research on patient portals has primarily focused on the outpatient setting. We explored whether health literacy and education were associated with portal usage in an inpatient population. Among 60,159 admissions in 2012–2013, 23.3% of patients reported limited health literacy; 50.4% reported some post-secondary education; 34.4% were registered for the portal; and 23.4% of registered patients used the portal during hospitalization. Probability of registration and inpatient portal use increased with educational attainment. Health literacy was associated with registration but not inpatient use. Among admissions with inpatient use, educational attainment was associated with viewing health record data, and health literacy was associated use of appointment and health education tools. The inpatient setting may provide an opportunity to overcome barriers to patient portal adoption and reduce disparities in use of health information technologies. PMID:26958286

  20. Ten Keys to the Portal

    ERIC Educational Resources Information Center

    Schaffhauser, Dian

    2011-01-01

    Successful web portals help users stay informed, in touch, and up to speed. They are also a telling window into the efficiency of one's institution. To develop a cutting-edge portal takes planning, communication, and research. In this article, the author presents and discusses 10 keys to portal success: (1) make critical info visible; (2) make the…

  1. Straddle carrier radiation portal monitoring

    NASA Astrophysics Data System (ADS)

    Andersen, Eric S.; Samuel, Todd J.; Mullen, O. Dennis

    2005-05-01

    U.S. Customs and Border Protection (CBP) is the primary enforcement agency protecting the nation"s ports of entry. CBP is enhancing its capability to interdict the illicit import of nuclear and radiological materials and devices that may be used by terrorists. Pacific Northwest National Laboratory (PNNL) is providing scientific and technical support to CBP in their goal to enable rapid deployment of nuclear and radiation detection systems at U. S. ports of entry to monitor 100% of the incoming international traffic and cargo while not adversely impacting the operations or throughput of the ports. The U.S. ports of entry include the following vectors: land border crossings, seaports, airports, rail crossings, and mail and express consignment courier facilities. U.S. Customs and Border Protection (CBP) determined that a screening solution was needed for Seaport cargo containers being transported by Straddle Carriers (straddle carriers). A stationary Radiation Portal Monitor (RPM) for Straddle Carriers (SCRPM) is needed so that cargo containers can be scanned while in transit under a Straddle Carrier. The Straddle Carrier Portal operational impacts were minimized by conducting a time-motion study at the Port, and adaptation of a Remotely Operated RPM (RO-RPM) booth concept that uses logical lighting schemes for traffic control, cameras, Optical Character Recognition, and wireless technology.

  2. Araport: the Arabidopsis information portal.

    PubMed

    Krishnakumar, Vivek; Hanlon, Matthew R; Contrino, Sergio; Ferlanti, Erik S; Karamycheva, Svetlana; Kim, Maria; Rosen, Benjamin D; Cheng, Chia-Yi; Moreira, Walter; Mock, Stephen A; Stubbs, Joseph; Sullivan, Julie M; Krampis, Konstantinos; Miller, Jason R; Micklem, Gos; Vaughn, Matthew; Town, Christopher D

    2015-01-01

    The Arabidopsis Information Portal (https://www.araport.org) is a new online resource for plant biology research. It houses the Arabidopsis thaliana genome sequence and associated annotation. It was conceived as a framework that allows the research community to develop and release 'modules' that integrate, analyze and visualize Arabidopsis data that may reside at remote sites. The current implementation provides an indexed database of core genomic information. These data are made available through feature-rich web applications that provide search, data mining, and genome browser functionality, and also by bulk download and web services. Araport uses software from the InterMine and JBrowse projects to expose curated data from TAIR, GO, BAR, EBI, UniProt, PubMed and EPIC CoGe. The site also hosts 'science apps,' developed as prototypes for community modules that use dynamic web pages to present data obtained on-demand from third-party servers via RESTful web services. Designed for sustainability, the Arabidopsis Information Portal strategy exploits existing scientific computing infrastructure, adopts a practical mixture of data integration technologies and encourages collaborative enhancement of the resource by its user community. PMID:25414324

  3. Straddle Carrier Radiation Portal Monitoring

    SciTech Connect

    Andersen, Eric S.; Samuel, Todd J.; Mullen, O Dennis

    2005-08-01

    U.S. Customs and Border Protection (CBP) is the primary enforcement agency protecting the nation’s ports of entry. CBP is enhancing its capability to interdict the illicit import of nuclear and radiological materials and devices that may be used by terrorists. Pacific Northwest National Laboratory (PNNL) is providing scientific and technical support to CBP in their goal to enable rapid deployment of nuclear and radiation detection systems at U. S. ports of entry to monitor 100% of the incoming international traffic and cargo while not adversely impacting the operations or throughput of the ports. The U.S. ports of entry include the following vectors: land border crossings, seaports, airports, rail crossings, and mail and express consignment courier facilities. U.S. Customs and Border Protection (CBP) determined that a screening solution was needed for Seaport cargo containers being transported by Straddle Carriers (straddle carriers). A stationary Radiation Portal Monitor (RPM) for Straddle Carriers (SCRPM) is needed so that cargo containers can be scanned while in transit under a Straddle Carrier. The Straddle Carrier Portal operational impacts were minimized by conducting a time-motion study at the Port, and adaptation of a Remotely Operated RPM (RO-RPM) booth concept that uses logical lighting schemes for traffic control, cameras, Optical Character Recognition, and wireless technology.

  4. Araport: the Arabidopsis Information Portal

    PubMed Central

    Krishnakumar, Vivek; Hanlon, Matthew R.; Contrino, Sergio; Ferlanti, Erik S.; Karamycheva, Svetlana; Kim, Maria; Rosen, Benjamin D.; Cheng, Chia-Yi; Moreira, Walter; Mock, Stephen A.; Stubbs, Joseph; Sullivan, Julie M.; Krampis, Konstantinos; Miller, Jason R.; Micklem, Gos; Vaughn, Matthew; Town, Christopher D.

    2015-01-01

    The Arabidopsis Information Portal (https://www.araport.org) is a new online resource for plant biology research. It houses the Arabidopsis thaliana genome sequence and associated annotation. It was conceived as a framework that allows the research community to develop and release ‘modules’ that integrate, analyze and visualize Arabidopsis data that may reside at remote sites. The current implementation provides an indexed database of core genomic information. These data are made available through feature-rich web applications that provide search, data mining, and genome browser functionality, and also by bulk download and web services. Araport uses software from the InterMine and JBrowse projects to expose curated data from TAIR, GO, BAR, EBI, UniProt, PubMed and EPIC CoGe. The site also hosts ‘science apps,’ developed as prototypes for community modules that use dynamic web pages to present data obtained on-demand from third-party servers via RESTful web services. Designed for sustainability, the Arabidopsis Information Portal strategy exploits existing scientific computing infrastructure, adopts a practical mixture of data integration technologies and encourages collaborative enhancement of the resource by its user community. PMID:25414324

  5. Portal hypertensive enteropathy

    PubMed Central

    Mekaroonkamol, Parit; Cohen, Robert; Chawla, Saurabh

    2015-01-01

    Portal hypertensive enteropathy (PHE) is a condition that describes the pathologic changes and mucosal abnormalities observed in the small intestine of patients with portal hypertension. This entity is being increasingly recognized and better understood over the past decade due to increased accessibility of the small intestine made possible by the introduction of video capsule endoscopy and deep enteroscopy. Though challenged by its diverse endoscopic appearance, multiple scoring systems have been proposed to classify the endoscopic presentation and grade its severity. Endoscopic findings can be broadly categorized into vascular and non-vascular lesions with many subtypes of both categories. Clinical manifestations of PHE can range from asymptomatic incidental findings to fatal gastrointestinal hemorrhage. Classic endoscopic findings in the setting of portal hypertension may lead to a prompt diagnosis. Occasionally histopathology and cross sectional imaging like computed tomography or magnetic resonance imaging may be helpful in establishing a diagnosis. Management of overt bleeding requires multidisciplinary approach involving hepatologists, endoscopists, surgeons, and interventional radiologists. Adequate resuscitation, reduction of portal pressure, and endoscopic therapeutic intervention remain the main principles of the initial treatment. This article reviews the existing evidence on PHE with emphasis on its classification, diagnosis, clinical manifestations, endoscopic appearance, pathological findings, and clinical management. A new schematic management of ectopic variceal bleed is also proposed. PMID:25729469

  6. Best Practices for Building Web Data Portals

    NASA Astrophysics Data System (ADS)

    Anderson, R. A.; Drew, L.

    2013-12-01

    technology, SEO rich content and more. As a result, it was on the first page of numerous related Google search results within 24 hours of the portal launch. 8) Build in-browser data analysis tools showing scientists how the data can be used in their research. The ASF DAAC Wetlands portal demonstrates that allowing the user to examine the data quickly and graphically online readily enables users to perceive the value of the data and how to use it. 9) Use responsive Web design (RWD) so content and tools can be accessed from a wide range of devices. Wetlands and Seasat can be accessed from smartphones, tablets and desktops. 10) Use Web frameworks to enable rapid building of new portals using consistent design patterns. Seasat and Wetlands both use Django and Twitter Bootstrap. 11) Use load-balanced servers if high demand for the data is anticipated. Using load-balanced servers for the Seasat and Wetlands portals allows ASF to simply add hardware as needed to support increased capacity. 12) Use open-source software when possible. Seasat and Wetlands portal development costs were reduced, and functionality was increased, with the use of open-source software. 13) Use third-party virtual servers (e.g. Amazon EC2 and S3 Services) where applicable. 14) Track visitors using analytic tools. 15) Continually improve design.

  7. Design of Grid Portal System Based on RIA

    NASA Astrophysics Data System (ADS)

    Cao, Caifeng; Luo, Jianguo; Qiu, Zhixin

    Grid portal is an important branch of grid research. In order to solve the weak expressive force, the poor interaction, the low operating efficiency and other insufficiencies of the first and second generation of grid portal system, RIA technology was introduced to it. A new portal architecture was designed based on RIA and Web service. The concrete realizing scheme of portal system was presented by using Adobe Flex/Flash technology, which formed a new design pattern. In system architecture, the design pattern has B/S and C/S superiorities, balances server and its client side, optimizes the system performance, realizes platform irrelevance. In system function, the design pattern realizes grid service call, provides client interface with rich user experience, integrates local resources by using FABridge, LCDS, Flash player and some other components.

  8. Knowledge portal: a tool to capture university requirements

    NASA Astrophysics Data System (ADS)

    Mansourvar, Marjan; Binti Mohd Yasin, Norizan

    2011-10-01

    New technologies, especially, the Internet have made a huge impact on knowledge management and information dissemination in education. The web portal as a knowledge management system is very popular topics in many organizations including universities. Generally, a web portal defines as a gateway to online network accessible resources through the intranet, extranet or Internet. This study develops a knowledge portal for the students in the Faculty of Computer Science and Information Technology (FCSIT), University of Malaya (UM). The goals of this portal are to provide information for the students to help them to choose the right courses and major that are relevant to their intended future jobs or career in IT. A quantitative approach used as the selected method for this research. Quantitative method provides an easy and useful way to collect data from a large sample population.

  9. Portal Annular Pancreas

    PubMed Central

    Harnoss, Jonathan M.; Harnoss, Julian C.; Diener, Markus K.; Contin, Pietro; Ulrich, Alexis B.; Büchler, Markus W.; Schmitz-Winnenthal, Friedrich H.

    2014-01-01

    Abstract Portal annular pancreas (PAP) is an asymptomatic congenital pancreas anomaly, in which portal and/or mesenteric veins are encased by pancreas tissue. The aim of the study was to determine the role of PAP in pancreatic surgery as well as its management and potential complication, specifically, postoperative pancreatic fistula (POPF). On the basis of a case report, the MEDLINE and ISI Web of Science databases were systematically reviewed up to September 2012. All articles describing a case of PAP were considered. In summary, 21 studies with 59 cases were included. The overall prevalence of PAP was 2.4% and the patients' mean (SD) age was 55.9 (16.2) years. The POPF rate in patients with PAP (12 pancreaticoduodenectomies and 3 distal pancreatectomies) was 46.7% (in accordance with the definition of the International Study Group of Pancreatic Surgery). Portal annular pancreas is a quite unattended pancreatic variant with high prevalence and therefore still remains a clinical challenge to avoid postoperative complications. To decrease the risk for POPF, attentive preoperative diagnostics should also focus on PAP. In pancreaticoduodenectomy, a shift of the resection plane to the pancreas tail should be considered; in extensive pancreatectomy, coverage of the pancreatic remnant by the falciform ligament could be a treatment option. PMID:25207658

  10. Transjugular Portal Venous Stenting in Inflammatory Extrahepatic Portal Vein Stenosis

    SciTech Connect

    Schaible, Rolf; Textor, Jochen; Decker, Pan; Strunk, Holger; Schild, Hans

    2002-12-15

    We report the case of a 37-year-old man with necrotizing pancreatitis associated with inflammatory extrahepatic portal vein stenosis and progressive ascites. Four months after the acute onset, when no signs of infection were present, portal decompression was performed to treat refractory ascites. Transjugulartranshepatic venoplasty failed to dilate the stenosis in the extrahepatic portion of the portal vein sufficiently. Therefore a Wallstent was implanted, resulting in almost normal diameter of the vessel. In follow-up imaging studies the stent and the portal vein were still patent 12 months after the intervention and total resolution of the ascites was observed.

  11. 29 CFR 785.24 - Principles noted in Portal-to-Portal Bulletin.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Principles noted in Portal-to-Portal Bulletin. 785.24... of Principles Preparatory and Concluding Activities § 785.24 Principles noted in Portal-to-Portal Bulletin. In November, 1947, the Administrator issued the Portal-to-Portal Bulletin (part 790 of...

  12. 29 CFR 785.24 - Principles noted in Portal-to-Portal Bulletin.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Principles noted in Portal-to-Portal Bulletin. 785.24... of Principles Preparatory and Concluding Activities § 785.24 Principles noted in Portal-to-Portal Bulletin. In November, 1947, the Administrator issued the Portal-to-Portal Bulletin (part 790 of...

  13. 29 CFR 785.24 - Principles noted in Portal-to-Portal Bulletin.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Principles noted in Portal-to-Portal Bulletin. 785.24... of Principles Preparatory and Concluding Activities § 785.24 Principles noted in Portal-to-Portal Bulletin. In November, 1947, the Administrator issued the Portal-to-Portal Bulletin (part 790 of...

  14. 29 CFR 785.24 - Principles noted in Portal-to-Portal Bulletin.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Principles noted in Portal-to-Portal Bulletin. 785.24... of Principles Preparatory and Concluding Activities § 785.24 Principles noted in Portal-to-Portal Bulletin. In November, 1947, the Administrator issued the Portal-to-Portal Bulletin (part 790 of...

  15. Collateral Pathways in Portal Hypertension

    PubMed Central

    Sharma, Malay; Rameshbabu, Chittapuram S.

    2012-01-01

    Presence of portosystemic collateral veins (PSCV) is common in portal hypertension due to cirrhosis. Physiologically, normal portosystemic anastomoses exist which exhibit hepatofugal flow. With the development of portal hypertension, transmission of backpressure leads to increased flow in these patent normal portosystemic anastomoses. In extrahepatic portal vein obstruction collateral circulation develops in a hepatopetal direction and portoportal pathways are frequently found. The objective of this review is to illustrate the various PSCV and portoportal collateral vein pathways pertinent to portal hypertension in liver cirrhosis and EHPVO. PMID:25755456

  16. It's a Bird. It's a Plane. It's a...Portal?: What Is a Campus Portal Strategy and Why Do You Need One?

    ERIC Educational Resources Information Center

    Katz, Richard N.

    2000-01-01

    Describes the results of a recent forum, and subsequent conference, on the subject of portals and e-business in higher education. Participants, who included financial and information technology professionals, agreed that implementation of portal strategy is necessary, perilous, and difficult in higher education. Colleges and universities will have…

  17. 8. Detail, skewed portal bracing at west portal, also showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Detail, skewed portal bracing at west portal, also showing boxed endposts, latticed upper transverse and diagonal sway bracing, laced vertical members, view to northeast, 210mm lens. - Southern Pacific Railroad Shasta Route, Bridge No. 301.85, Milepost 301.85, Pollard Flat, Shasta County, CA

  18. Portal Vein Thrombosis in Cirrhosis

    PubMed Central

    Raja, Kaiser; Jacob, Mathew; Asthana, Sonal

    2013-01-01

    Portal vein thrombosis (PVT) is being increasingly recognized in patients with advanced cirrhosis and in those undergoing liver transplantation. Reduced flow in the portal vein is probably responsible for clotting in the spleno-porto-mesenteric venous system. There is also increasing evidence that hypercoagulability occurs in advanced liver disease and contributes to the risk of PVT. Ultrasound based studies have reported a prevalence of PVT in 10–25% of cirrhotic patients without hepatocellular carcinoma. Partial thrombosis of the portal vein is more common and may not have pathophysiological consequences. However, there is high risk of progression of partial PVT to complete PVT that may cause exacerbation of portal hypertension and progression of liver insufficiency. It is thus, essential to accurately diagnose and stage PVT in patients waiting for transplantation and consider anticoagulation therapy. Therapy with low molecular weight heparin and vitamin K antagonists has been shown to achieve complete and partial recanalization in 33–45% and 15–35% of cases respectively. There are however, no guidelines to help determine the dose and therapeutic efficacy of anticoagulation in patients with cirrhosis. Anticoagulation therapy related bleeding is the most feared complication but it appears that the risk of variceal bleeding is more likely to be dependent on portal pressure rather than solely related to coagulation status. TIPS has also been reported to restore patency of the portal vein. Patients with complete PVT currently do not form an absolute contraindication for liver transplantation. Thrombectomy or thromboendovenectomy is possible in more than 75% of patients followed by anatomical end-to-end portal anastomosis. When patency of the portal vein and/or superior mesenteric vein is not achieved, only non-anatomical techniques (reno-portal anastomosis or cavo-portal hemitransposition) can be performed. These techniques, which do not fully reverse portal

  19. The DIRAC Web Portal 2.0

    NASA Astrophysics Data System (ADS)

    Mathe, Z.; Casajus Ramo, A.; Lazovsky, N.; Stagni, F.

    2015-12-01

    For many years the DIRAC interware (Distributed Infrastructure with Remote Agent Control) has had a web interface, allowing the users to monitor DIRAC activities and also interact with the system. Since then many new web technologies have emerged, therefore a redesign and a new implementation of the DIRAC Web portal were necessary, taking into account the lessons learnt using the old portal. These new technologies allowed to build a more compact, robust and responsive web interface that enables users to have better control over the whole system while keeping a simple interface. The web framework provides a large set of “applications”, each of which can be used for interacting with various parts of the system. Communities can also create their own set of personalised web applications, and can easily extend already existing ones with a minimal effort. Each user can configure and personalise the view for each application and save it using the DIRAC User Profile service as RESTful state provider, instead of using cookies. The owner of a view can share it with other users or within a user community. Compatibility between different browsers is assured, as well as with mobile versions. In this paper, we present the new DIRAC Web framework as well as the LHCb extension of the DIRAC Web portal.

  20. Of Portals, Policies, and Poets

    ERIC Educational Resources Information Center

    Bunt, Rick; Pennock, Lea

    2006-01-01

    Universities are drawn to portals as an effective way of organizing and delivering campus services and information. In a university environment, where the desire for local autonomy and the impetus for centralization are in constant tension, a portal seems especially appealing because it allows local solutions through a shared medium. But the fact…

  1. All Roads Lead to Portal

    ERIC Educational Resources Information Center

    Heid, Susan D.

    2007-01-01

    Portals are taking off on campuses nationwide. According to "Campus Computing 2006," the Campus Computing Project's survey of 540 two- and four-year public and private colleges and universities across the US, portal deployment for four-year public residential universities jumped from 28 to 74 percent of responding institutions between the…

  2. The Power in the Portal

    ERIC Educational Resources Information Center

    Chamberlain, Cathy

    2005-01-01

    Educational portals put together links to sites and resources educators would be interested in viewing. They eliminate the hours of searching that might be invested if typical search engines were used. Educational portals feature lessons, units, printable resources, creative ideas, and more. Many of these sites are free, while others are…

  3. NSTA Portal to Science Safety

    ERIC Educational Resources Information Center

    Roy, Ken

    2010-01-01

    The National Science Teachers Association's (NSTA) Science Safety Advisory Board recently launched the Safety in the Science Classroom portal. This portal serves as a gateway to safety resources for teachers, supervisors, and administrators. It also contains an evolving list of safety resources for elementary, middle, and high schools. The list…

  4. Web portal on environmental sciences "ATMOS''

    NASA Astrophysics Data System (ADS)

    Gordov, E. P.; Lykosov, V. N.; Fazliev, A. Z.

    2006-06-01

    The developed under INTAS grant web portal ATMOS (http://atmos.iao.ru and http://atmos.scert.ru) makes available to the international research community, environmental managers, and the interested public, a bilingual information source for the domain of Atmospheric Physics and Chemistry, and the related application domain of air quality assessment and management. It offers access to integrated thematic information, experimental data, analytical tools and models, case studies, and related information and educational resources compiled, structured, and edited by the partners into a coherent and consistent thematic information resource. While offering the usual components of a thematic site such as link collections, user group registration, discussion forum, news section etc., the site is distinguished by its scientific information services and tools: on-line models and analytical tools, and data collections and case studies together with tutorial material. The portal is organized as a set of interrelated scientific sites, which addressed basic branches of Atmospheric Sciences and Climate Modeling as well as the applied domains of Air Quality Assessment and Management, Modeling, and Environmental Impact Assessment. Each scientific site is open for external access information-computational system realized by means of Internet technologies. The main basic science topics are devoted to Atmospheric Chemistry, Atmospheric Spectroscopy and Radiation, Atmospheric Aerosols, Atmospheric Dynamics and Atmospheric Models, including climate models. The portal ATMOS reflects current tendency of Environmental Sciences transformation into exact (quantitative) sciences and is quite effective example of modern Information Technologies and Environmental Sciences integration. It makes the portal both an auxiliary instrument to support interdisciplinary projects of regional environment and extensive educational resource in this important domain.

  5. The astrophysics simulation collaboratory : a science portal enabling community software development.

    SciTech Connect

    Russell, M.; Allen, G.; Daues, G.; Foster, I.; Seidel, E.; Novotny, J.; Shalf, J.; von Laszewski, G.; Mathematics and Computer Science; Max-Planck-Inst.; Univ. of Chicago; LBNL; National Center for Supercomputing Applications; Washington Univ.

    2002-01-01

    Grid Portals, based on standard web technologies, are emerging as important and useful user interfaces to computational and data Grids. Grid Portals enable Virtual Organizations, comprised of distributed researchers to collaborate and access resources more efficiently and seamlessly. The Astrophysics Simulation Collaboratory (ASC) Grid Portal provides a framework to enable researchers in the field of numerical relativity to study astrophysical phenomenon by making use of the Cactus computational toolkit. We examine user requirements and describe the design and implementation of the ASC Grid Portal.

  6. The Portuguese Climate Portal

    NASA Astrophysics Data System (ADS)

    Gomes, Sandra; Deus, Ricardo; Nogueira, Miguel; Viterbo, Pedro; Miranda, Miguel; Antunes, Sílvia; Silva, Alvaro; Miranda, Pedro

    2016-04-01

    The Portuguese Local Warming Website (http://portaldoclima.pt) has been developed in order to support the society in Portugal in preparing for the adaptation to the ongoing and future effects of climate change. The climate portal provides systematic and easy access to authoritative scientific data ready to be used by a vast and diverse user community from different public and private sectors, key players and decision makers, but also to high school students, contributing to the increase in knowledge and awareness on climate change topics. A comprehensive set of regional climate variables and indicators are computed, explained and graphically presented. Variables and indicators were built in agreement with identified needs after consultation of the relevant social partners from different sectors, including agriculture, water resources, health, environment and energy and also in direct cooperation with the Portuguese National Strategy for Climate Change Adaptation (ENAAC) group. The visual interface allows the user to dynamically interact, explore, quickly analyze and compare, but also to download and import the data and graphics. The climate variables and indicators are computed from state-of-the-art regional climate model (RCM) simulations (e.g., CORDEX project), at high space-temporal detail, allowing to push the limits of the projections down to local administrative regions (NUTS3) and monthly or seasonal periods, promoting local adaptation strategies. The portal provides both historical data (observed and modelled for the 1971-2000 period) and future climate projections for different scenarios (modelled for the 2011-2100 period). A large effort was undertaken in order to quantify the impacts of the risk of extreme events, such as heavy rain and flooding, droughts, heat and cold waves, and fires. Furthermore the different climate scenarios and the ensemble of RCM models, with high temporal (daily) and spatial (~11km) detail, is taken advantage in order to

  7. A Comparative Study of Campus Portal User Acceptance: Student and Faculty Perspectives

    ERIC Educational Resources Information Center

    Abuhamdieh, Ayman H.; Sehwail, Loay

    2007-01-01

    This study examined campus portal module use patterns and its user acceptance. A random sample is collected and the Technology Acceptance Model (TAM) is used to explore student and faculty perceptions of the portal's ease of use and usefulness. These perceptions are contrasted to find any significant differences between the two groups. Study…

  8. The parallel virtual file system for portals.

    SciTech Connect

    Schutt, James Alan

    2004-04-01

    This report presents the result of an effort to re-implement the Parallel Virtual File System (PVFS) using Portals as the transport. This report provides short overviews of PVFS and Portals, and describes the design and implementation of PVFS over Portals. Finally, the results of performance testing of both stock PVFS and PVFS over Portals are presented.

  9. 29 CFR 785.34 - Effect of section 4 of the Portal-to-Portal Act.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Effect of section 4 of the Portal-to-Portal Act. 785.34 Section 785.34 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... of Principles Traveltime § 785.34 Effect of section 4 of the Portal-to-Portal Act. The Portal...

  10. 29 CFR 785.34 - Effect of section 4 of the Portal-to-Portal Act.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Effect of section 4 of the Portal-to-Portal Act. 785.34 Section 785.34 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... of Principles Traveltime § 785.34 Effect of section 4 of the Portal-to-Portal Act. The Portal...

  11. 29 CFR 785.34 - Effect of section 4 of the Portal-to-Portal Act.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Effect of section 4 of the Portal-to-Portal Act. 785.34 Section 785.34 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... of Principles Traveltime § 785.34 Effect of section 4 of the Portal-to-Portal Act. The Portal...

  12. The ENSEMBLES Statistical Downscaling Portal

    NASA Astrophysics Data System (ADS)

    Cofino, Antonio S.; San-Martín, Daniel; Gutiérrez, Jose M.

    2010-05-01

    The demand for high-resolution seasonal and ACC predictions is continuously increasing due to the multiple end-user applications in a variety of sectors (hydrology, agronomy, energy, etc.) which require regional meteorological inputs. To fill the gap between the coarse-resolution grids used by global weather models and the regional needs of applications, a number of statistical downscaling techniques have been proposed. Statistical downscaling is a complex multi-disciplinary problem which requires a cascade of different scientific tools to access and process different sources of data, from GCM outputs to local observations and to run complex statistical algorithms. Thus, an end-to-end approach is needed in order to link the outputs of the ensemble prediction systems to a range of impact applications. To accomplish this task in an interactive and user-friendly form, a Web portal has been developed within the European ENSEMBLES project, integrating the necessary tools and providing the appropriate technology for distributed data access and computing. In this form, users can obtain their downscaled data testing and validating different statistical methods (from the categories weather typing, regression or weather generators) in a transparent form, not worrying about the details of the downscaling techniques and the data formats and access.

  13. A Look at Success for Data Portals (Invited)

    NASA Astrophysics Data System (ADS)

    White, C. E.

    2013-12-01

    As a member of Esri's Geoportal Server team for the past six years, I have been involved in hundreds of customer portal, geoportal, and spatial data infrastructure implementations. Our team's goal for each implementation is - of course- for it to be successful. A successful data portal can be defined by a number of indicators. The foremost measure of success is that the target end users are able to easily find and access data that meets their needs. Other indicators are effectiveness of the user interface, interoperability mechanisms to enhance discoverability and usability across contexts, compliance with data sharing mandates, extendibility/portability of the system as technology evolves, and staff expertise to maintain the system. Further, some data portals have not only been successful by these measures but have also challenged and expanded the state of the art in the areas of discovery, access, and managing data. This talk will address models, principles, and best practices for deploying data portals that are successful by these measures, identify examples of excellence in the field, and discuss upcoming advances in portal technology to support scientists in sharing their work.

  14. Climate Outreach Using Regional Coastal Ocean Observing System Portals

    NASA Astrophysics Data System (ADS)

    Anderson, D. M.; Hernandez, D. L.; Wakely, A.; Bochenek, R. J.; Bickel, A.

    2015-12-01

    Coastal oceans are dynamic, changing environments affected by processes ranging from seconds to millennia. On the east and west coast of the U.S., regional observing systems have deployed and sustained a remarkable diverse array of observing tools and sensors. Data portals visualize and provide access to real-time sensor networks. Portals have emerged as an interactive tool for educators to help students explore and understand climate. Bringing data portals to outreach events, into classrooms, and onto tablets and smartphones enables educators to address topics and phenomena happening right now. For example at the 2015 Charleston Science Technology Engineering and Math (STEM) Festival, visitors navigated the SECOORA (Southeast Coastal Ocean Observing regional Association) data portal to view the real-time marine meteorological conditions off South Carolina. Map-based entry points provide an intuitive interface for most students, an array of time series and other visualizations depict many of the essential principles of climate science manifest in the coastal zone, and data down-load/ extract options provide access to the data and documentation for further inquiry by advanced users. Beyond the exposition of climate principles, the portal experience reveals remarkable technologies in action and shows how the observing system is enabled by the activity of many different partners.

  15. Hidden Magnetic Portals Around Earth

    NASA Video Gallery

    A NASA-sponsored researcher at the University of Iowa has developed a way for spacecraft to hunt down hidden magnetic portals in the vicinity of Earth. These gateways link the magnetic field of our...

  16. Clinical use of electronic portal imaging.

    PubMed

    Herman, Michael G

    2005-07-01

    Accurate and routine target localization is necessary for successful outcome in radiation therapy treatments. Electronic portal imaging devices (EPIDs) provide an advanced tool with digital technology to improve target localization and maintain clinical efficiency. EPIDs are ubiquitous in the radiation therapy clinic, and they provide a powerful and flexible tool to collect and process data in a quantitative manner to improve treatment accuracy for virtually any treatment site. This manuscript provides an overview of the clinical implementation process for effective use of EPIDs. It continues with a review of correction strategies and finally highlights numerous examples of effective clinical application of EPID. PMID:15983941

  17. The quail anatomy portal.

    PubMed

    Ruparelia, Avnika A; Simkin, Johanna E; Salgado, David; Newgreen, Donald F; Martins, Gabriel G; Bryson-Richardson, Robert J

    2014-01-01

    The Japanese quail is a widely used model organism for the study of embryonic development; however, anatomical resources are lacking. The Quail Anatomy Portal (QAP) provides 22 detailed three-dimensional (3D) models of quail embryos during development from embryonic day (E)1 to E15 generated using optical projection tomography. The 3D models provided can be virtually sectioned to investigate anatomy. Furthermore, using the 3D nature of the models, we have generated a tool to assist in the staging of quail samples. Volume renderings of each stage are provided and can be rotated to allow visualization from multiple angles allowing easy comparison of features both between stages in the database and between images or samples in the laboratory. The use of JavaScript, PHP and HTML ensure the database is accessible to users across different operating systems, including mobile devices, facilitating its use in the laboratory.The QAP provides a unique resource for researchers using the quail model. The ability to virtually section anatomical models throughout development provides the opportunity for researchers to virtually dissect the quail and also provides a valuable tool for the education of students and researchers new to the field. DATABASE URL: http://quail.anatomyportal.org (For review username: demo, password: quail123). PMID:24715219

  18. Leveraging Industry Standards for GeoSpatial Portal Development

    NASA Astrophysics Data System (ADS)

    Zimble, D.; Garegnani, J. J.

    2005-12-01

    Rapid advances in mainstream IT data sharing techniques through the leveraging of mainstream IT standards such as the World Wide Web Consortium (W3C) extensible markup language (XML), simple object access protocol (SOAP) based web services and the Java Community Process (JCP) driven portlet technology (JSR-0168) in addition to the wide adoption of Open Geospatial Consortium (OGC) GIS web service specifications (WMS, WFS, WCS, WMC, CS-W etc.) are intersecting within commercial GIS technologies. For example, the next generation GIS Portal technology for the U.S. Government's Geospatial One-Stop has been developed to help establish an industrial strength geospatial portal that can be used as the primary U.S. Government coordinating portal for geospatial related activities. In addition to these technologies providing common highly interoperable portals, heavier desktop and server applications are further integrating technologies that will enable the scientific communities to link into these mainstream information portals. By example, we will discuss the incorporation of the Open Source scripting language known as Python into the commercial GIS platform both on the desktop and on the server. For example, users have already developed python code that can be deployed providing the GIS user access to large repositories of scientific multidimensional data via the OpeNDAP protocol that can be incorporated into the GIS analysis and workflow. Additional development in the support of NetCDF and in the future additional scientific data formats will expand the use of such formats within the GIS community. This presentation will provide an overview and demonstrations of these technologies and how they are relevant to the Earth and Space Science Informatics Community.

  19. The Higgs portal above threshold

    NASA Astrophysics Data System (ADS)

    Craig, Nathaniel; Lou, Hou Keong; McCullough, Matthew; Thalapillil, Arun

    2016-02-01

    The discovery of the Higgs boson opens the door to new physics interacting via the Higgs Portal, including motivated scenarios relating to baryogenesis, dark matter, and electroweak naturalness. We systematically explore the collider signatures of singlet scalars produced via the Higgs Portal at the 14 TeV LHC and a prospective 100 TeV hadron collider. We focus on the challenging regime where the scalars are too heavy to be produced in the decays of an on-shell Higgs boson, and instead are produced primarily via an off-shell Higgs. Assuming these scalars escape the detector, promising channels include missing energy in association with vector boson fusion, monojets, and top pairs. We forecast the sensitivity of searches in these channels at √{s}=14 & 100 TeV and compare collider reach to the motivated parameter space of singlet-assisted electroweak baryogenesis, Higgs Portal dark matter, and neutral naturalness.

  20. Web Portal for Multicast Delivery Management.

    ERIC Educational Resources Information Center

    Mannaert, H.; De Gruyter, B.; Adriaenssens, P.

    2003-01-01

    Presents a Web portal for multicast communication management, which provides fully automatic service management with integrated provisioning of hardware equipment. Describes the software architecture, the implementation, and the application usage of the Web portal for multicast delivery. (Author/AEF)

  1. 29 CFR 785.50 - Section 4 of the Portal-to-Portal Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Section 4 of the Portal-to-Portal Act. 785.50 Section 785.50 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... Provisions § 785.50 Section 4 of the Portal-to-Portal Act. Section 4 of this Act provides that: (a) Except...

  2. 29 CFR 785.50 - Section 4 of the Portal-to-Portal Act.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Section 4 of the Portal-to-Portal Act. 785.50 Section 785.50 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... Provisions § 785.50 Section 4 of the Portal-to-Portal Act. Section 4 of this Act provides that: (a) Except...

  3. 29 CFR 785.50 - Section 4 of the Portal-to-Portal Act.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Section 4 of the Portal-to-Portal Act. 785.50 Section 785.50 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... Provisions § 785.50 Section 4 of the Portal-to-Portal Act. Section 4 of this Act provides that: (a) Except...

  4. 29 CFR 785.50 - Section 4 of the Portal-to-Portal Act.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Section 4 of the Portal-to-Portal Act. 785.50 Section 785.50 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... Provisions § 785.50 Section 4 of the Portal-to-Portal Act. Section 4 of this Act provides that: (a) Except...

  5. 29 CFR 785.50 - Section 4 of the Portal-to-Portal Act.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Section 4 of the Portal-to-Portal Act. 785.50 Section 785.50 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... Provisions § 785.50 Section 4 of the Portal-to-Portal Act. Section 4 of this Act provides that: (a) Except...

  6. Unusual Tumors Causing Extrahepatic Portal Venous Obstruction

    PubMed Central

    Sharma, B. C.; Dhiman, R. K.; Ghoshal, U. C.; Puri, A. S.; Sikora, S. S.

    1996-01-01

    Extrahepatic portal vein obstruction has been reported to be associated with tumors of liver, bile ducts and pancreas. We report two cases, one with gastric leiomyosarcoma and another with Non Hodgkin’s lymphoma, complicated by portal vein block and presenting with gastric variceal bleeding. Portal vein block in both cases was due to direct vascular infiltration. Development of portal hypertension posed difficulties in management. PMID:8725458

  7. The MISTRALS programme data portal

    NASA Astrophysics Data System (ADS)

    Fleury, Laurence; Brissebrat, Guillaume; Belmahfoud, Nizar; Boichard, Jean-Luc; Brosolo, Laetitia; Cloché, Sophie; Descloitres, Jacques; Ferré, Hélène; Focsa, Loredana; Henriot, Nicolas; Labatut, Laurent; Mière, Arnaud; Petit de la Villéon, Loïc; Ramage, Karim; Schmechtig, Catherine; Vermeulen, Anne; André, François

    2015-04-01

    Mediterranean Integrated STudies at Regional And Local Scales (MISTRALS) is a decennial programme for systematic observations and research dedicated to the understanding of the Mediterranean Basin environmental process and its evolution under the planet global change. It is composed of eight multidisciplinary projects that cover all the components of the Earth system (atmosphere, ocean, continental surfaces, lithosphere...) and their interactions, all the disciplines (physics, chemistry, marine biogeochemistry, biology, geology, sociology...) and different time scales. For example Hydrological cycle in the Mediterranean eXperiment (HyMeX) aims at improving the predictability of rainfall extreme events, and assessing the social and economic vulnerability to extreme events and adaptation capacity. Paleo Mediterranean Experiment (PaleoMeX) is dedicated to the study of the interactions between climate, societies and civilizations of the Mediterranean world during the last 10000 years. Many long term monitoring research networks are associated with MISTRALS, such as Mediterranean Ocean Observing System on Environment (MOOSE), Centre d'Observation Régional pour la Surveillance du Climat et de l'environnement Atmosphérique et océanographique en Méditerranée occidentale (CORSICA) and the environmental observations from Mediterranean Eurocentre for Underwater Sciences and Technologies (MEUST-SE). Therefore, the data generated or used by the different MISTRALS projects are very heterogeneous. They include in situ observations, satellite products, model outputs, social sciences surveys... Some datasets are automatically produced by operational networks, and others come from research instruments and analysis procedures. They correspond to different time scales (historical time series, observatories, campaigns...) and are managed by several data centres. They originate from many scientific communities, with different data sharing practices, specific expectations and using

  8. The MISTRALS programme data portal

    NASA Astrophysics Data System (ADS)

    Brissebrat, Guillaume; Albert-Aguilar, Alexandre; Belmahfoud, Nizar; Cloché, Sophie; Darras, Sabine; Descloitres, Jacques; Ferré, Hélène; Fleury, Laurence; Focsa, Loredana; Henriot, Nicolas; Labatut, Laurent; Petit de la Villéon, Loïc; Ramage, Karim; Schmechtig, Catherine; Vermeulen, Anne

    2016-04-01

    Mediterranean Integrated STudies at Regional And Local Scales (MISTRALS) is a decennial programme for systematic observations and research dedicated to the understanding of the Mediterranean Basin environmental process and its evolution under the planet global change. It is composed of eight multidisciplinary projects that cover all the components of the Earth system (atmosphere, ocean, continental surfaces, lithosphere...) and their interactions, all the disciplines (physics, chemistry, marine biogeochemistry, biology, geology, sociology...) and different time scales. For example Hydrological cycle in the Mediterranean eXperiment (HyMeX) aims at improving the predictability of rainfall extreme events, and assessing the social and economic vulnerability to extreme events and adaptation capacity. Paleo Mediterranean Experiment (PaleoMeX) is dedicated to the study of the interactions between climate, societies and civilizations of the Mediterranean world during the last 10000 years. Many long term monitoring research networks are associated with MISTRALS, such as Mediterranean Ocean Observing System on Environment (MOOSE), Centre d'Observation Régional pour la Surveillance du Climat et de l'environnement Atmosphérique et océanographique en Méditerranée occidentale (CORSICA) and the environmental observations from Mediterranean Eurocentre for Underwater Sciences and Technologies (MEUST-SE). Therefore, the data generated or used by the different MISTRALS projects are very heterogeneous. They include in situ observations, satellite products, model outputs, social sciences surveys... Some datasets are automatically produced by operational networks, and others come from research instruments and analysis procedures. They correspond to different time scales (historical time series, observatories, campaigns...) and are managed by several data centres. They originate from many scientific communities, with different data sharing practices, specific expectations and using

  9. The MISTRALS programme data portal

    NASA Astrophysics Data System (ADS)

    Fleury, Laurence; Brissebrat, Guillaume; Belmahfoud, Nizar; Boichard, Jean-Luc; Brosolo, Laetitia; Cloché, Sophie; Descloitres, Jacques; Ferré, Hélène; Focsa, Loredana; Labatut, Laurent; Mastrorillo, Laurence; Mière, Arnaud; Petit de la Villéon, Loïc; Ramage, Karim; Schmechtig, Catherine

    2014-05-01

    Mediterranean Integrated STudies at Regional And Local Scales (MISTRALS) is a decennial programme for systematic observations and research dedicated to the understanding of the Mediterranean Basin environmental process and its evolution under the planet global change. It is composed of eight multidisciplinary projects that cover all the components of the Earth system (atmosphere, ocean, continental surfaces, lithosphere...) and their interactions, many disciplines (physics, chemistry, marine biogeochemistry, biology, geology, sociology...) and different time scales. For example Hydrological cycle in the Mediterranean eXperiment (HyMeX) aims at improving the predictability of rainfall extreme events, and assessing the social and economic vulnerability to extreme events and adaptation capacity, and Paleo Mediterranean Experiment (PaleoMeX) is dedicated to the study of the interactions between climate, societies and civilizations of the Mediterranean world during the last 10000 years. Many long term monitoring research networks are associated with MISTRALS, like Mediterranean Ocean Observing System on Environment (MOOSE), Centre d'Observation Régional pour la Surveillance du Climat et de l'environnement Atmosphérique et océanographique en Méditerranée occidentale (CORSICA) and the environmental observations from Mediterranean Eurocentre for Underwater Sciences and Technologies (MEUST-SE). Therefore, the data generated or used by the different MISTRALS projects are very heterogeneous. They include in situ observations, satellite products, model outputs, qualitative field surveys... Some datasets are automatically produced by operational networks, and others come from research instruments and analysis procedures. They correspond to different time scales (historical time series, observatories, campaigns...) and are managed by different data centres. They originate from many scientific communities, with varied data sharing cultures, specific expectations, and using

  10. From EGEE Operations Portal towards EGI Operations Portal

    NASA Astrophysics Data System (ADS)

    Cordier, Hélène; L'Orphelin, Cyril; Reynaud, Sylvain; Lequeux, Olivier; Loikkanen, Sinikka; Veyre, Pierre

    Grid operators in EGEE have been using a dedicated dashboard as their central operational tool, stable and scalable for the last 5 years despite continuous upgrade from specifications by users, monitoring tools or data providers. In EGEE-III, recent regionalisation of operations led the Operations Portal developers to conceive a standalone instance of this tool. We will see how the dashboard reorganization paved the way for the re-engineering of the portal itself. The outcome is an easily deployable package customized with relevant information sources and specific decentralized operational requirements. This package is composed of a generic and scalable data access mechanism, Lavoisier; a renowned php framework for configuration flexibility, Symfony and a MySQL database. VO life cycle and operational information, EGEE broadcast and Downtime notifications are next for the major reorganization until all other key features of the Operations Portal are migrated to the framework. Features specifications will be sketched at the same time to adapt to EGI requirements and to upgrade. Future work on feature regionalisation, on new advanced features or strategy planning will be tracked in EGI- Inspire through the Operations Tools Advisory Group, OTAG, where all users, customers and third parties of the Operations Portal are represented from January 2010.

  11. VisEL: Visualisation of Expertise Level in a Special Interest Group Knowledge Portal

    NASA Astrophysics Data System (ADS)

    Zulhafizsyam Wan Ahmad, Wan Muhammad; Sulaiman, Shahida; Yusof, Umi Kalsom

    A variety of portals are available nowadays to support diverse purposes such as commercial, publishing, personal, affinity and corporate portals. Affinity portals promote electronic communities who share common interest such as a special interest group (SIG). Knowledge portal is an emerging trend that benefits the existing portal technology by designing such portals with proper representation of the members' shared knowledge. Besides textual representation for diverse expertise levels, graphical visualisation will be able to support the requirements in searching and representing expertise level among e-community. There is a number of existing SIG portals available. However, they do not visualise effectively and accurately the expertise level of members and make it difficult for users to search their targeted experts for instance searching the highest expertise level to have a discussion and to solve their problems related to a project. The goal of this paper is to propose a graphical visualisation of expertise level method (VisEL) using an interactive tag cloud technique that represents expertise level of each member based on their knowledge in a software engineering SIG portal.

  12. Portal Monitor Future Development Work: Hardware Improvements

    SciTech Connect

    Browne, Michael C.

    2012-07-03

    LANL portal monitor was a modification of a previously installed (permanent) unattended monitoring system (UMS). Modifications to the UMS to make the portal were sometimes based on mistaken assumptions about exercise-specific installation and access. Philosophical approach to real-time portal differs in some areas from UMS.

  13. 29 CFR 790.5 - Effect of Portal-to-Portal Act on determination of hours worked.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Effect of Portal-to-Portal Act on determination of hours... GENERAL STATEMENT AS TO THE EFFECT OF THE PORTAL-TO-PORTAL ACT OF 1947 ON THE FAIR LABOR STANDARDS ACT OF... Effect of Portal-to-Portal Act on determination of hours worked. (a) In the application of the...

  14. 29 CFR 790.5 - Effect of Portal-to-Portal Act on determination of hours worked.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Effect of Portal-to-Portal Act on determination of hours... GENERAL STATEMENT AS TO THE EFFECT OF THE PORTAL-TO-PORTAL ACT OF 1947 ON THE FAIR LABOR STANDARDS ACT OF... Effect of Portal-to-Portal Act on determination of hours worked. (a) In the application of the...

  15. 29 CFR 790.5 - Effect of Portal-to-Portal Act on determination of hours worked.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Effect of Portal-to-Portal Act on determination of hours... GENERAL STATEMENT AS TO THE EFFECT OF THE PORTAL-TO-PORTAL ACT OF 1947 ON THE FAIR LABOR STANDARDS ACT OF... Effect of Portal-to-Portal Act on determination of hours worked. (a) In the application of the...

  16. 29 CFR 790.5 - Effect of Portal-to-Portal Act on determination of hours worked.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Effect of Portal-to-Portal Act on determination of hours... GENERAL STATEMENT AS TO THE EFFECT OF THE PORTAL-TO-PORTAL ACT OF 1947 ON THE FAIR LABOR STANDARDS ACT OF... Effect of Portal-to-Portal Act on determination of hours worked. (a) In the application of the...

  17. 29 CFR 785.34 - Effect of section 4 of the Portal-to-Portal Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Effect of section 4 of the Portal-to-Portal Act. 785.34... of Principles Traveltime § 785.34 Effect of section 4 of the Portal-to-Portal Act. The Portal Act... it. (See Tennessee Coal, Iron & RR. Co. v. Musecoda Local, 321 U.S. 590 (1946); Anderson v....

  18. 29 CFR 785.34 - Effect of section 4 of the Portal-to-Portal Act.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Effect of section 4 of the Portal-to-Portal Act. 785.34... of Principles Traveltime § 785.34 Effect of section 4 of the Portal-to-Portal Act. The Portal Act... even if the employer agrees to pay for it. (See Tennessee Coal, Iron & RR. Co. v. Musecoda Local, 321...

  19. X-ray absorption fine structure spectroscopic determination of plutonium speciation at the Rocky Flats environmental technology

    SciTech Connect

    Lezama-pacheco, Juan S; Conradson, Steven D; Clark, David L

    2008-01-01

    X-ray Absorption Fine Structure spectroscopy was used to probe the speciation of the ppm level Pu in thirteen soil and concrete samples from the Rocky Flats Environmental Technology Site in support of the site remediation effort that has been successfully completed since these measurements. In addition to X-ray Absorption Near Edge Spectra, two of the samples yielded Extended X-ray Absorption Fine Structure spectra that could be analyzed by curve-fits. Most of these spectra exhibited features consistent with PU(IV), and more specificaJly, PuO{sub 2+x}-type speciation. Two were ambiguous, possibly indicating that Pu that was originally present in a different form was transforming into PuO{sub 2+x}, and one was interpreted as demonstrating the presence of an unusual Pu(VI) compound, consistent with its source being spills from a PUREX purification line onto a concrete floor and the resultant extreme conditions. These experimental results therefore validated models that predicted that insoluble PuO{sub 2+x} would be the most stable form of Pu in equilibrium with air and water even when the source terms were most likely Pu metal with organic compounds or a Pu fire. A corollary of these models' predictions and other in situ observations is therefore that the minimal transport of Pu that occurred on the site was via the resuspension and mobilization of colloidal particles. Under these conditions, the small amounts of diffusely distributed Pu that were left on the site after its remediation pose only a negligible hazard.

  20. VisPortal: Deploying grid-enabled visualization tools through a web-portal interface

    SciTech Connect

    Bethel, Wes; Siegerist, Cristina; Shalf, John; Shetty, Praveenkumar; Jankun-Kelly, T.J.; Kreylos, Oliver; Ma, Kwan-Liu

    2003-06-09

    The LBNL/NERSC Visportal effort explores ways to deliver advanced Remote/Distributed Visualization (RDV) capabilities through a Grid-enabled web-portal interface. The effort focuses on latency tolerant distributed visualization algorithms, GUI designs that are more appropriate for the capabilities of web interfaces, and refactoring parallel-distributed applications to work in a N-tiered component deployment strategy. Most importantly, our aim is to leverage commercially-supported technology as much as possible in order to create a deployable, supportable, and hence viable platform for delivering grid-based visualization services to collaboratory users.

  1. Ed Blogs: A Vygotsky Dialectivist Technology Portal

    ERIC Educational Resources Information Center

    Hargis, Jace; Schofield, Kathleen

    2006-01-01

    This article provides a brief history of Web logging and subsequent examples of Web log use specific to an educational arena. Although the blogging phenomenon began a few years ago, it is only recently that a critical mass of educators has realized its potential in and out of the classroom for teaching and learning content while acting as a…

  2. The new IAGOS Database Portal

    NASA Astrophysics Data System (ADS)

    Boulanger, Damien; Gautron, Benoit; Thouret, Valérie; Fontaine, Alain

    2016-04-01

    IAGOS (In-service Aircraft for a Global Observing System) is a European Research Infrastructure which aims at the provision of long-term, regular and spatially resolved in situ observations of the atmospheric composition. IAGOS observation systems are deployed on a fleet of commercial aircraft. The IAGOS database is an essential part of the global atmospheric monitoring network. It contains IAGOS-core data and IAGOS-CARIBIC (Civil Aircraft for the Regular Investigation of the Atmosphere Based on an Instrument Container) data. The IAGOS Database Portal (http://www.iagos.fr, damien.boulanger@obs-mip.fr) is part of the French atmospheric chemistry data center AERIS (http://www.aeris-data.fr). The new IAGOS Database Portal has been released in December 2015. The main improvement is the interoperability implementation with international portals or other databases in order to improve IAGOS data discovery. In the frame of the IGAS project (IAGOS for the Copernicus Atmospheric Service), a data network has been setup. It is composed of three data centers: the IAGOS database in Toulouse; the HALO research aircraft database at DLR (https://halo-db.pa.op.dlr.de); and the CAMS data center in Jülich (http://join.iek.fz-juelich.de). The CAMS (Copernicus Atmospheric Monitoring Service) project is a prominent user of the IGAS data network. The new portal provides improved and new services such as the download in NetCDF or NASA Ames formats, plotting tools (maps, time series, vertical profiles, etc.) and user management. Added value products are available on the portal: back trajectories, origin of air masses, co-location with satellite data, etc. The link with the CAMS data center, through JOIN (Jülich OWS Interface), allows to combine model outputs with IAGOS data for inter-comparison. Finally IAGOS metadata has been standardized (ISO 19115) and now provides complete information about data traceability and quality.

  3. Portal biliopathy treated with endoscopic biliary stenting

    PubMed Central

    Jeon, Sung Jin; Min, Jae Ki; Kwon, So Young; Kim, Jun Hyun; Moon, Sun Young; Lee, Kang Hoon; Kim, Jeong Han; Choe, Won Hyeok; Cheon, Young Koog; Kim, Tae Hyung; Park, Hee Sun

    2016-01-01

    Portal biliopathy is defined as abnormalities in the extra- and intrahepatic ducts and gallbladder of patients with portal hypertension. This condition is associated with extrahepatic venous obstruction and dilatation of the venous plexus of the common bile duct, resulting in mural irregularities and compression of the biliary tree. Most patients with portal biliopathy remain asymptomatic, but approximately 10% of them advance to symptomatic abdominal pain, jaundice, and fever. Magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography are currently used as diagnostic tools because they are noninvasive and can be used to assess the regularity, length, and degree of bile duct narrowing. Management of portal biliopathy is aimed at biliary decompression and reducing the portal pressure. Portal biliopathy has rarely been reported in Korea. We present a symptomatic case of portal biliopathy that was complicated by cholangitis and successfully treated with biliary endoscopic procedures. PMID:27044769

  4. 1. West portal of the mudshed abutting the west portal ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. West portal of the mudshed abutting the west portal of Tunnel 5, view to the northwest, 135mm lens. The flat-roofed reinforced concrete mudsheds, rocksheds, and snowsheds are a common feature of the Natron Cutoff over the summit of the Cascades. With the railroad located on a sidehill bench cut into the precipitous slopes, the sheds protect the track from rock and mud slides, as well as from avalanches. With a solid wall on the uphill side and a series of columns on the downhill side, they form a gallery-like effect from within. This mudshed was built concurrent with the tunnel, in 1927. Though none of the mudsheds on the line are scheduled to be modified, this shed was documented as an integral element of Tunnel 5. - Southern Pacific Railroad Natron Cutoff, Tunnel 5, Milepost 545.2, McCredie Springs, Lane County, OR

  5. Quality evaluation of portal sites in health system, as a tool for education and learning

    PubMed Central

    Hejazi, Sayed Mehdi; Sarmadi, Sima

    2013-01-01

    Background: The main objective of creating a portal is to make information service available for users who need them for performance of duties and responsibilities regardless of the sources. This article is attempted to consider the parameters that can evaluate these sites since these criteria can be effective in designing and implementing such portals. On the other hand, portal sites in health systems of every country make it possible for leaders, policy makers, and directors to system education as a tool for new learning technologies. One of the main decisions each manager has to make is precise selection of appropriate portal sites. Materials and Methods: This is a descriptive and qualitative study. The research sample was 53 computer professional working in the area of computer programming and design. In the first part of the study a questionnaire was send to the participants and in the second part of the study based on their response to the questionnaire the participant was interviewed and the main themes of the studies were formulated. The validity and the reliability of the questionnaire were confirmed. Results: The study results were summarized in 10 themes and 50 sub-categories. The main themes included were portal requirements, security, management, and efficiency, user friendliness, built-in applications, portal flexibility, interoperability, and support systems. Conclusion: Portal sites in any education systems make it possible for health system leaders and policy makers to manage their organization information system efficiently and effectively. One of the major decisions each manager has to make is precise selection of an appropriate portal sites design and development. The themes and sub-categories of this study could help health system managers and policy makers and information technology professionals to make appropriate decisions regarding portal design and development. PMID:24520554

  6. An Internet Portal for the Development of Clinical Practice Guidelines

    PubMed Central

    Höhne, W.J.; Karge, T.; Siegmund, B.; Preiss, J.; Hoffmann, J.C.; Zeitz, M.; Fölsch, U.R.

    2010-01-01

    Background The complexity and quality requirements for the development of clinical practice guidelines steadily increase. Internet technologies support this process by optimizing the development process. Objective The aim of this internet based solution was to facilitate the development of clinical practice guidelines. Methods An internet portal was developed allowing for a shared workplace to support clinical practice guideline authoring. It is based on a Content Management System and combines different tools for document handling and editing, communication as well as process and team steering. Results Until now, the internet portal has been successfully implicated in the development of six evidence- and consensus-based clinical practice guidelines. Additional German and European clinical practice guidelines are currently generated with support of the internet portal. The available tools allow for a flexible design of the scheduled workflow, depending on the requirements of the respective group. An additional strength of the platform is the advantage to transfer all data from a previous version of a guideline into the next ‘life-cycle’. Conclusion The application of the portal results in a considerable reduction of costs and development time of the resulting clinical practice guidelines. PMID:23616852

  7. Potential for portal detection of human chemical and biological contamination

    NASA Astrophysics Data System (ADS)

    Settles, Gary S.; McGann, William J.

    2001-08-01

    The walk-through metal-detection portal is a paradigm of non-intrusive passenger screening in aviation security. Modern explosive detection portals based on this paradigm will soon appear in airports. This paper suggests that the airborne trace detection technology developed for that purpose can also be adapted to human chemical and biological contamination. The waste heat of the human body produces a rising warm-air sheath of 50-80 liters/sec known as the human thermal plume. Contained within this plume are hundreds of bioeffluents from perspiration and breath, and millions of skin flakes. Since early medicine, the airborne human scent was used in the diagnosis of disease. Recent examples also include toxicity and substance abuse, but this approach has never been quantified. The appearance of new bioeffluents or subtle changes in the steady-state may signal the onset of a chemical/biological attack. Portal sampling of the human thermal plume is suggested, followed by a pre-concentration step and the detection of the attacking agent or the early human response. The ability to detect nanogram levels of explosive trace contamination this way was already demonstrated. Key advantages of the portal approach are its rapidity and non-intrusiveness, and the advantage that it does not require the traditional bodily fluid or tissue sampling.

  8. Vertical flow chemical detection portal

    DOEpatents

    Linker, Kevin L.; Hannum, David W.; Conrad, Frank James

    1999-01-01

    A portal apparatus for screening objects or persons for the presence of trace amounts of chemical substances such as illicit drugs or explosives. The apparatus has a test space, in which a person may stand, defined by two generally upright sides spanned by a horizontal transom. One or more fans in the transom generate a downward air flow (uni-directional) within the test space. The air flows downwardly from a high pressure upper zone, past the object or person to be screened. Air moving past the object dislodges from the surface thereof both volatile and nonvolatile particles of the target substance. The particles are entrained into the air flow which continues flowing downward to a lower zone of reduced pressure, where the particle-bearing air stream is directed out of the test space and toward preconcentrator and detection components. The sides of the portal are specially configured to partially contain and maintain the air flow.

  9. Vertical flow chemical detection portal

    DOEpatents

    Linker, K.L.; Hannum, D.W.; Conrad, F.J.

    1999-06-22

    A portal apparatus is described for screening objects or persons for the presence of trace amounts of chemical substances such as illicit drugs or explosives. The apparatus has a test space, in which a person may stand, defined by two generally upright sides spanned by a horizontal transom. One or more fans in the transom generate a downward air flow (uni-directional) within the test space. The air flows downwardly from a high pressure upper zone, past the object or person to be screened. Air moving past the object dislodges from the surface thereof both volatile and nonvolatile particles of the target substance. The particles are entrained into the air flow which continues flowing downward to a lower zone of reduced pressure, where the particle-bearing air stream is directed out of the test space and toward preconcentrator and detection components. The sides of the portal are specially configured to partially contain and maintain the air flow. 3 figs.

  10. Two-portal dark matter

    NASA Astrophysics Data System (ADS)

    Ghorbani, Karim; Ghorbani, Hossein

    2015-06-01

    We propose a renormalizable dark matter model in which a fermionic dark matter (DM) candidate communicates with the standard model particles through two distinct portals: Higgs and vector portals. The dark sector is charged under a U (1 )' gauge symmetry while the standard model has a leptophobic interaction with the dark vector boson. The leading contribution of the DM-nucleon elastic scattering cross section begins at one-loop level. The model meets all the constraints imposed by direct detection experiments provided by LUX and XENON100, observed relic abundance according to WMAP and Planck, and the invisible Higgs decay width measured at the LHC. It turns out that the dark matter mass in the viable parameter space can take values from a few GeV up to 1 TeV. This is a new feature which is absent in the models with only one portal. In addition, we can find in the constrained regions of the parameter space a DM mass of ˜34 GeV annihilating into b quark pair, which explains the Fermi-LAT gamma-ray excess.

  11. Z-portal dark matter

    SciTech Connect

    Arcadi, Giorgio; Mambrini, Yann; Richard, Francois

    2015-03-11

    We propose to generalize the extensions of the Standard Model where the Z boson serves as a mediator between the Standard Model sector and the dark sector χ. We show that, like in the Higgs portal case, the combined constraints from the recent direct searches restrict severely the nature of the coupling of the dark matter to the Z boson and set a limit m{sub χ}≳200 GeV (except in a very narrow region around the Z-pole region). Using complementarity between spin dependent, spin independent and FERMI limits, we predict the nature of this coupling, more specifically the axial/vectorial ratio that respects a thermal dark matter coupled through a Z-portal while not being excluded by the current observations. We also show that the next generation of experiments of the type LZ or XENON1T will test Z-portal scenario for dark matter mass up to 2 TeV. The condition of a thermal dark matter naturally predicts the spin-dependent scattering cross section on the neutron to be σ{sub χn}{sup SD}≃10{sup −40} cm{sup 2}, which then becomes a clear prediction of the model and a signature testable in the near future experiments.

  12. [Mexican consensus on portal hypertension].

    PubMed

    Narváez-Rivera, R M; Cortez-Hernández, C A; González-González, J A; Tamayo-de la Cuesta, J L; Zamarripa-Dorsey, F; Torre-Delgadillo, A; Rivera-Ramos, J F J; Vinageras-Barroso, J I; Muneta-Kishigami, J E; Blancas-Valencia, J M; Antonio-Manrique, M; Valdovinos-Andraca, F; Brito-Lugo, P; Hernández-Guerrero, A; Bernal-Reyes, R; Sobrino-Cossío, S; Aceves-Tavares, G R; Huerta-Guerrero, H M; Moreno-Gómez, N; Bosques-Padilla, F J

    2013-01-01

    The aim of the Mexican Consensus on Portal Hypertension was to develop documented guidelines to facilitate clinical practice when dealing with key events of the patient presenting with portal hypertension and variceal bleeding. The panel of experts was made up of Mexican gastroenterologists, hepatologists, and endoscopists, all distinguished professionals. The document analyzes themes of interest in the following modules: preprimary and primary prophylaxis, acute variceal hemorrhage, and secondary prophylaxis. The management of variceal bleeding has improved considerably in recent years. Current information indicates that the general management of the cirrhotic patient presenting with variceal bleeding should be carried out by a multidisciplinary team, with such an approach playing a major role in the final outcome. The combination of drug and endoscopic therapies is recommended for initial management; vasoactive drugs should be started as soon as variceal bleeding is suspected and maintained for 5 days. After the patient is stabilized, urgent diagnostic endoscopy should be carried out by a qualified endoscopist, who then performs the corresponding endoscopic variceal treatment. Antibiotic prophylaxis should be regarded as an integral part of treatment, started upon hospital admittance and continued for 5 days. If there is treatment failure, rescue therapies should be carried out immediately, taking into account that interventional radiology therapies are very effective in controlling refractory variceal bleeding. These guidelines have been developed for the purpose of achieving greater clinical efficacy and are based on the best evidence of portal hypertension that is presently available. PMID:23664429

  13. Uzbekistan Radiation Portal Monnitoring System

    SciTech Connect

    Richardson, J; Knapp, R; Loshak, A; Yuldashev, B; Petrenko, V

    2005-06-10

    The work proposed in this presentation builds on the foundation set by the DTRA funded demonstration project begun in 2000 and completed in December of 2003. This previous work consisted of two phases whose overall objective was to install portal radiation monitors at four select ports-of-entry in Uzbekistan (Tashkent International Airport, Gisht-Kuprik (Kazakhstan border), Alat (Turkmenistan border), and Termez (Afghanistan border)) in order to demonstrate their effectiveness in preventing the illicit trafficking of nuclear materials. The objectives also included developing and demonstrating capabilities in the design, installation, operation, training, and maintenance of a radiation portal monitoring system. The system and demonstration project has proved successful in many ways. An effective working relationship among the Uzbekistan Customs Services, Uzbekistan Border Guards, and Uzbekistan Institute of Nuclear Physics has been developed. There has been unprecedented openness with the sharing of portal monitor data with Lawrence Livermore National Laboratory. The system has proved to be effective, with detection of illicit trafficking, and, at Alat, an arrest of three persons illegally transporting radioactive materials into Turkmenistan. The demonstration project has made Uzbekistan a model nonproliferation state in Central Asia and, with an expanded program, places them in a position to seal a likely transit route for illicit nuclear materials. These results will be described. In addition, this work is currently being expanded to include additional ports-of-entry in Uzbekistan. The process for deciding on which additional ports-of-entry to equip will also be described.

  14. 2. West portal of Tunnel 27, contextual view from track ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. West portal of Tunnel 27, contextual view from track level east of Tunnel 26 (HAER CA-202), 210mm lens. Note solar panel providing signal power, evidence of continuing updating of technology by the railroad. Single-light searchlight-type signal was typical system-wide on the Southern Pacific prior to the 1980s merger with the Denver & Rio Grande Western. - Central Pacific Transcontinental Railroad, Tunnel No. 27, Milepost 133.9, Applegate, Placer County, CA

  15. Development of XML Schema for Broadband Digital Seismograms and Data Center Portal

    NASA Astrophysics Data System (ADS)

    Takeuchi, N.; Tsuboi, S.; Ishihara, Y.; Nagao, H.; Yamagishi, Y.; Watanabe, T.; Yanaka, H.; Yamaji, H.

    2008-12-01

    There are a number of data centers around the globe, where the digital broadband seismograms are opened to researchers. Those centers use their own user interfaces and there are no standard to access and retrieve seismograms from different data centers using unified interface. One of the emergent technologies to realize unified user interface for different data centers is the concept of WebService and WebService portal. Here we have developed a prototype of data center portal for digital broadband seismograms. This WebService portal uses WSDL (Web Services Description Language) to accommodate differences among the different data centers. By using the WSDL, alteration and addition of data center user interfaces can be easily managed. This portal, called NINJA Portal, assumes three WebServices: (1) database Query service, (2) Seismic event data request service, and (3) Seismic continuous data request service. Current system supports both station search of database Query service and seismic continuous data request service. Data centers supported by this NINJA portal will be OHP data center in ERI and Pacific21 data center in IFREE/JAMSTEC in the beginning. We have developed metadata standard for seismological data based on QuakeML for parametric data, which has been developed by ETH Zurich, and XML-SEED for waveform data, which was developed by IFREE/JAMSTEC. The prototype of NINJA portal is now released through IFREE web page (http://www.jamstec.go.jp/pacific21/).

  16. Portal hypertension complicating myelofibrosis: reversal following splenectomy.

    PubMed Central

    Lukie, B. E.; Card, R. T.

    1977-01-01

    Portal hypertension occurs in approximately 10% of patients with myelofibrosis. Increased portal blood flow secondary to splenomegaly has been proposed to explain its development. In a 60-year-old woman with proven myelofibrosis of 10 years' duration and gross splenomegaly, portal hypertension developed with esophageal varices and ascites. There was no demonstrable obstruction to portal blood flow. Following splenectomy the ascites and esophageal varices disappeared. Despite the presence of splenic myeloid metaplasia, splenectomy did not impair the patient's hematologic status. Portal hypertension complicating myelofibrosis has a poor prognosis, so careful attention should be given to its detection. Splenectomy may be preferable to portal-systemic shunting in the management of this complication. Images FIG. 1 FIG. 2 PMID:907949

  17. Noncirrhotic portal fibrosis after Wilms' tumor therapy

    SciTech Connect

    Barnard, J.A.; Marshall, G.S.; Neblett, W.W.; Gray, G.; Ghishan, F.K.

    1986-04-01

    A 9-yr-old girl developed massive hemorrhage from esophageal varices 2 yr after combined modality therapy for Wilms' tumor. Evaluation showed a patent extrahepatic portal venous system and an elevated splenic pulp pressure. In contrast to previous reports of hepatopathy after irradiation injury, histologic sections of the liver did not demonstrate occlusion of the central veins, but rather a diffuse obliteration of intrahepatic portal venous radicles. This pattern of noncirrhotic portal fibrosis has not been described following antitumor therapy.

  18. Preduodenal portal vein: its surgical significance.

    PubMed

    Makey, D A; Bowen, J C

    1978-11-01

    Preduodenal portal vein is a rare anatomical variant which may be one of many anomalies in the neonate with duodenal "atresia." Preduodenal portal vein also may be an occasional finding in an adult undergoing biliary, gastric, or pancreatic surgery. Awareness and recognition of the anomaly are essential for the avoidance of injury during such operations. We report here a symptomless patient whose preduodenal portal vein was discovered at cholecystectomy. PMID:715684

  19. Portal hypertension: pathophysiology, diagnosis, and treatment.

    PubMed

    Buob, S; Johnston, A N; Webster, C R L

    2011-01-01

    Portal hypertension (PH) is the result of increased vascular resistance in the portal circulation, increased portal venous blood flow, or both. In veterinary medicine, where portal pressure is seldom measured directly, the diagnosis of PH often is inferred from identification of associated complications including multiple acquired portosystemic shunts, ascites, and hepatic encephalopathy. Likewise, treatment of PH primarily is aimed at controlling these complications. The goal of this review is to provide an update on the pathophysiology, diagnosis, and treatment of PH. The review draws from information in the veterinary hepatology literature, reviews, and consensus statements in human hepatology and the literature on experimental models of PH. PMID:21382073

  20. Web-based Service Portal in Healthcare

    NASA Astrophysics Data System (ADS)

    Silhavy, Petr; Silhavy, Radek; Prokopova, Zdenka

    Information delivery is one the most important task in healthcare. The growing sector of electronic healthcare has an important impact on the information delivery. There are two basic approaches towards information delivering. The first is web portal and second is touch-screen terminal. The aim of this paper is to investigate the web-based service portal. The most important advantage of web-based portal in the field of healthcare is an independent access for patients. This paper deals with the conditions and frameworks for healthcare portals

  1. Tsunami.gov: NOAA's Tsunami Information Portal

    NASA Astrophysics Data System (ADS)

    Shiro, B.; Carrick, J.; Hellman, S. B.; Bernard, M.; Dildine, W. P.

    2014-12-01

    We present the new Tsunami.gov website, which delivers a single authoritative source of tsunami information for the public and emergency management communities. The site efficiently merges information from NOAA's Tsunami Warning Centers (TWC's) by way of a comprehensive XML feed called Tsunami Event XML (TEX). The resulting unified view allows users to quickly see the latest tsunami alert status in geographic context without having to understand complex TWC areas of responsibility. The new site provides for the creation of a wide range of products beyond the traditional ASCII-based tsunami messages. The publication of modern formats such as Common Alerting Protocol (CAP) can drive geographically aware emergency alert systems like FEMA's Integrated Public Alert and Warning System (IPAWS). Supported are other popular information delivery systems, including email, text messaging, and social media updates. The Tsunami.gov portal allows NOAA staff to easily edit content and provides the facility for users to customize their viewing experience. In addition to access by the public, emergency managers and government officials may be offered the capability to log into the portal for special access rights to decision-making and administrative resources relevant to their respective tsunami warning systems. The site follows modern HTML5 responsive design practices for optimized use on mobile as well as non-mobile platforms. It meets all federal security and accessibility standards. Moving forward, we hope to expand Tsunami.gov to encompass tsunami-related content currently offered on separate websites, including the NOAA Tsunami Website, National Tsunami Hazard Mitigation Program, NOAA Center for Tsunami Research, National Geophysical Data Center's Tsunami Database, and National Data Buoy Center's DART Program. This project is part of the larger Tsunami Information Technology Modernization Project, which is consolidating the software architectures of NOAA's existing TWC's into

  2. Patient portals - An online tool for your health

    MedlinePlus

    A patient portal is a website for your personal health care. The online tool helps you to keep track of ... questions through the portal. Many providers now offer patient portals. For access, you will need to set up ...

  3. Design Considerations for Patient Portal Adoption by Low-Income, Older Adults

    PubMed Central

    Latulipe, Celine; Gatto, Amy; Nguyen, Ha T.; Miller, David P.; Quandt, Sara A.; Bertoni, Alain G.; Smith, Alden; Arcury, Thomas A.

    2016-01-01

    This paper describes the results of an interview study investigating facilitators and barriers to adoption of patient portals among low-income, older adults in rural and urban populations in the southeastern United States. We describe attitudes of this population of older adults and their current level of technology use and patient portal use. From qualitative analysis of 36 patient interviews and 16 caregiver interviews within these communities, we derive themes related to benefits of portals, barriers to use, concerns and desired features. Based on our initial findings, we present a set of considerations for designing the patient portal user experience, aimed at helping healthcare clinics to meet U.S. federally-mandated ‘meaningful use’ requirements. PMID:27077140

  4. Customizable scientific web-portal for DIII-D nuclear fusion experiment

    NASA Astrophysics Data System (ADS)

    Abla, G.; Kim, E. N.; Schissel, D. P.

    2010-04-01

    Increasing utilization of the Internet and convenient web technologies has made the web-portal a major application interface for remote participation and control of scientific instruments. While web-portals have provided a centralized gateway for multiple computational services, the amount of visual output often is overwhelming due to the high volume of data generated by complex scientific instruments and experiments. Since each scientist may have different priorities and areas of interest in the experiment, filtering and organizing information based on the individual user's need can increase the usability and efficiency of a web-portal. DIII-D is the largest magnetic nuclear fusion device in the US. A web-portal has been designed to support the experimental activities of DIII-D researchers worldwide. It offers a customizable interface with personalized page layouts and list of services for users to select. Each individual user can create a unique working environment to fit his own needs and interests. Customizable services are: real-time experiment status monitoring, diagnostic data access, interactive data analysis and visualization. The web-portal also supports interactive collaborations by providing collaborative logbook, and online instant announcement services. The DIII-D web-portal development utilizes multi-tier software architecture, and Web 2.0 technologies and tools, such as AJAX and Django, to develop a highly-interactive and customizable user interface.

  5. A Knowledge Portal and Collaboration Environment for the Earth Sciences

    NASA Astrophysics Data System (ADS)

    D'Agnese, F. A.

    2008-12-01

    Earth Knowledge is developing a web-based 'Knowledge Portal and Collaboration Environment' that will serve as the information-technology-based foundation of a modular Internet-based Earth-Systems Monitoring, Analysis, and Management Tool. This 'Knowledge Portal' is essentially a 'mash- up' of web-based and client-based tools and services that support on-line collaboration, community discussion, and broad public dissemination of earth and environmental science information in a wide-area distributed network. In contrast to specialized knowledge-management or geographic-information systems developed for long- term and incremental scientific analysis, this system will exploit familiar software tools using industry standard protocols, formats, and APIs to discover, process, fuse, and visualize existing environmental datasets using Google Earth and Google Maps. An early form of these tools and services is being used by Earth Knowledge to facilitate the investigations and conversations of scientists, resource managers, and citizen-stakeholders addressing water resource sustainability issues in the Great Basin region of the desert southwestern United States. These ongoing projects will serve as use cases for the further development of this information-technology infrastructure. This 'Knowledge Portal' will accelerate the deployment of Earth- system data and information into an operational knowledge management system that may be used by decision-makers concerned with stewardship of water resources in the American Desert Southwest.

  6. Stakeholder Expectations of Service Quality in a University Web Portal

    NASA Astrophysics Data System (ADS)

    Tate, Mary; Evermann, Joerg; Hope, Beverley; Barnes, Stuart

    Online service quality is a much-studied concept. There is considerable evidence that user expectations and perceptions of self-service and online service quality differ in different business domains. In addition, the nature of online services is continually changing and universities have been at the forefront of this change, with university websites increasingly acting as a portal for a wide range of online transactions for a wide range of stakeholders. In this qualitative study, we conduct focus groups with a range of stakeholders in a university web portal. Our study offers a number of insights into the changing nature of the relationship between organisations and customers. New technologies are influencing customer expectations. Customers increasingly expect organisations to have integrated information systems, and to utilise new technologies such as SMS and web portals. Organisations can be slow to adopt a customer-centric viewpoint, and persist in providing interfaces that are inconsistent or require inside knowledge of organisational structures and processes. This has a negative effect on customer perceptions.

  7. NEWT, a new taxonomy portal.

    PubMed

    Phan, I Q H; Pilbout, S F; Fleischmann, W; Bairoch, A

    2003-07-01

    NEWT is a new taxonomy portal to the SWISS-PROT protein sequence knowledgebase. It contains taxonomy data, which is updated daily, for the complete set of species represented in SWISS-PROT, as well as those stored at the NCBI. Users can navigate through the taxonomy tree and access corresponding SWISS-PROT protein entries. In addition, a manually curated selection of external links allows access to specific information on selected species. NEWT is available at http://www.ebi.ac.uk/newt/. PMID:12824428

  8. NEWT, a new taxonomy portal

    PubMed Central

    Phan, I. Q. H.; Pilbout, S. F.; Fleischmann, W.; Bairoch, A.

    2003-01-01

    NEWT is a new taxonomy portal to the SWISS-PROT protein sequence knowledgebase. It contains taxonomy data, which is updated daily, for the complete set of species represented in SWISS-PROT, as well as those stored at the NCBI. Users can navigate through the taxonomy tree and access corresponding SWISS-PROT protein entries. In addition, a manually curated selection of external links allows access to specific information on selected species. NEWT is available at http://www.ebi.ac.uk/newt/. PMID:12824428

  9. Portal hypertensive polyps, a new entity?

    PubMed

    Martín Domínguez, Verónica; Díaz Méndez, Ariel; Santander, Cecilio; García-Buey, Luisa

    2016-05-01

    We present a case of a 62 year old woman with history of liver cirrhosis secondary to autoimmune hepatitis, with portal hypertension and coagulopathy. Gastroscopy findings were a polypoid and polylobed lesions in the gastric antrum. These were removed and the pathological study described hyperplastic polyps with edema, vascular congestion and hyperplasia of smooth muscle, corresponding to "portal hypertensive polyps" (PHP). PMID:27188590

  10. Factors Affecting Faculty Web Portal Usability

    ERIC Educational Resources Information Center

    Bringula, Rex P.; Basa, Roselle S.

    2011-01-01

    The study investigated the factors that might significantly affect web portal usability. Results of the study were intended to serve as inputs for faculty web portal development of the University of the East-Manila. Descriptive statistics utilized questionnaire data from 82 faculty members. The data showed that most of the respondents were…

  11. Pancreatic pseudocyst rupture into the portal vein.

    PubMed

    Dawson, Brian C; Kasa, David; Mazer, Mark A

    2009-07-01

    A patient with a pancreatic pseudocyst rupture into the portal vein with a resultant noninfectious systemic inflammatory response syndrome and subsequent portal vein thrombosis diagnosed by computed tomography and ultrasonography is reported. A review of the existing English literature on this rare complication is also provided. PMID:19561436

  12. Idiopathic noncirrhotic portal hypertension: current perspectives.

    PubMed

    Riggio, Oliviero; Gioia, Stefania; Pentassuglio, Ilaria; Nicoletti, Valeria; Valente, Michele; d'Amati, Giulia

    2016-01-01

    The term idiopathic noncirrhotic portal hypertension (INCPH) has been recently proposed to replace terms, such as hepatoportal sclerosis, idiopathic portal hypertension, incomplete septal cirrhosis, and nodular regenerative hyperplasia, used to describe patients with a hepatic presinusoidal cause of portal hypertension of unknown etiology, characterized by features of portal hypertension (esophageal varices, nonmalignant ascites, porto-venous collaterals), splenomegaly, patent portal, and hepatic veins and no clinical and histological signs of cirrhosis. Physicians should learn to look for this condition in a number of clinical settings, including cryptogenic cirrhosis, a disease known to be associated with INCPH, drug administration, and even chronic alterations in liver function tests. Once INCPH is clinically suspected, liver histology becomes mandatory for the correct diagnosis. However, pathologists should be familiar with the histological features of INCPH, especially in cases in which histology is not only requested to exclude liver cirrhosis. PMID:27555800

  13. Idiopathic noncirrhotic portal hypertension: current perspectives

    PubMed Central

    Riggio, Oliviero; Gioia, Stefania; Pentassuglio, Ilaria; Nicoletti, Valeria; Valente, Michele; d’Amati, Giulia

    2016-01-01

    The term idiopathic noncirrhotic portal hypertension (INCPH) has been recently proposed to replace terms, such as hepatoportal sclerosis, idiopathic portal hypertension, incomplete septal cirrhosis, and nodular regenerative hyperplasia, used to describe patients with a hepatic presinusoidal cause of portal hypertension of unknown etiology, characterized by features of portal hypertension (esophageal varices, nonmalignant ascites, porto-venous collaterals), splenomegaly, patent portal, and hepatic veins and no clinical and histological signs of cirrhosis. Physicians should learn to look for this condition in a number of clinical settings, including cryptogenic cirrhosis, a disease known to be associated with INCPH, drug administration, and even chronic alterations in liver function tests. Once INCPH is clinically suspected, liver histology becomes mandatory for the correct diagnosis. However, pathologists should be familiar with the histological features of INCPH, especially in cases in which histology is not only requested to exclude liver cirrhosis. PMID:27555800

  14. The virtual space exploration education portal

    NASA Astrophysics Data System (ADS)

    Oliver, C. A.

    2007-06-01

    New information technologies have evolved from space exploration—3-D visualisation ‘lenses’ and a growing suite of tools that allow access to exploration, analysis and interpretation of often complex information by a range of end users including the public, communicators, and policy makers. These tools have only become viable in the past year or two with the combination of the availability of inexpensive, but powerful, personal computers and widespread use of the Internet. A new study group under Commission 6 has been established, entitled ‘Future Directions of Space Exploration Education’, to build a Virtual Global Space Exploration Education Portal (VGSEEP) to open this revolution to all audiences, not just students. This paper describes the initial stages of VGSEEP. The NASA Learning Technologies suite of ‘lenses’ and tools will be demonstrated: World Wind, a 3-D globe that provides insights into our planet from space and almost down to ground level; the Virtual Field Trip that explores at ground level in 3-D; the Virtual Lab, which allows a range of samples to be examined via a virtual light microscope and/or a Scanning Electron Microscope and What’s the Difference?, which allows users to manipulate information in a multi-graphical interface.

  15. A Modeling Environment for Patient Portals

    PubMed Central

    Duncavage, Sean; Mathe, Janos; Werner, Jan; Malin, Bradley A.; Ledeczi, Akos; Sztipanovits, Janos

    2007-01-01

    Clinical Information Systems (CIS) are complex environments that integrate information technologies, humans, and patient data. Given the sensitivity of patient data, federal regulations require health care providers to define privacy and security policies and to deploy enforcement technologies. The introduction of model-based design techniques, combined with the development of high-level modeling abstractions and analysis methods, provide a mechanism to investigate these concerns by conceptually simplifying CIS without sacrificing expressive power. This work introduces the Model-based Design Environment for Clinical Information Systems (MODECIS), which is a graphical design environment that assists CIS architects in formalizing systems and services. MODECIS leverages Service-Oriented Architectures to create realistic system models as abstractions. MODECIS enables the analysis of legacy architectures and the design and simulation of future CIS. We present the feasibility of MODECIS by modeling operations, such as user authentication, of MyHealth@Vanderbilt, a real world patient portal in use at the Vanderbilt University Medical Center. PMID:18693826

  16. Isocurvature constraints on portal couplings

    NASA Astrophysics Data System (ADS)

    Kainulainen, Kimmo; Nurmi, Sami; Tenkanen, Tommi; Tuominen, Kimmo; Vaskonen, Ville

    2016-06-01

    We consider portal models which are ultraweakly coupled with the Standard Model, and confront them with observational constraints on dark matter abundance and isocurvature perturbations. We assume the hidden sector to contain a real singlet scalar s and a sterile neutrino ψ coupled to s via a pseudoscalar Yukawa term. During inflation, a primordial condensate consisting of the singlet scalar s is generated, and its contribution to the isocurvature perturbations is imprinted onto the dark matter abundance. We compute the total dark matter abundance including the contributions from condensate decay and nonthermal production from the Standard Model sector. We then use the Planck limit on isocurvature perturbations to derive a novel constraint connecting dark matter mass and the singlet self coupling with the scale of inflation: mDM/GeV lesssim 0.2λs3/8 (H*/1011 GeV)‑3/2. This constraint is relevant in most portal models ultraweakly coupled with the Standard Model and containing light singlet scalar fields.

  17. Regional Ocean Data Portal: Transforming Information to Knowledge

    NASA Astrophysics Data System (ADS)

    Howard, M. K.; Gayanilo, F. C.; Jochens, A. E.

    2009-12-01

    producers, recreational boaters, etc.) workshops were held to elicit user needs and requirements for observing system products for each group. The GCOOS-RA’s Products and Services Committee and Education and Outreach Council have gone through similar activities aimed at determining what products various users groups want. We have been sensitive to the private sector when deciding which products to produce. While science users want numbers, users of all types mainly want maps. We have tried to develop flexible capabilities within the portal that helps users to create their own fused products, ad hoc, for a variety of output devices, from desktop screens to the smart phones. We will discuss how our data management system has evolved within the backdrop of rapidly changing technologies and diverse community requirements.

  18. The BioMart community portal: an innovative alternative to large, centralized data repositories.

    PubMed

    Smedley, Damian; Haider, Syed; Durinck, Steffen; Pandini, Luca; Provero, Paolo; Allen, James; Arnaiz, Olivier; Awedh, Mohammad Hamza; Baldock, Richard; Barbiera, Giulia; Bardou, Philippe; Beck, Tim; Blake, Andrew; Bonierbale, Merideth; Brookes, Anthony J; Bucci, Gabriele; Buetti, Iwan; Burge, Sarah; Cabau, Cédric; Carlson, Joseph W; Chelala, Claude; Chrysostomou, Charalambos; Cittaro, Davide; Collin, Olivier; Cordova, Raul; Cutts, Rosalind J; Dassi, Erik; Di Genova, Alex; Djari, Anis; Esposito, Anthony; Estrella, Heather; Eyras, Eduardo; Fernandez-Banet, Julio; Forbes, Simon; Free, Robert C; Fujisawa, Takatomo; Gadaleta, Emanuela; Garcia-Manteiga, Jose M; Goodstein, David; Gray, Kristian; Guerra-Assunção, José Afonso; Haggarty, Bernard; Han, Dong-Jin; Han, Byung Woo; Harris, Todd; Harshbarger, Jayson; Hastings, Robert K; Hayes, Richard D; Hoede, Claire; Hu, Shen; Hu, Zhi-Liang; Hutchins, Lucie; Kan, Zhengyan; Kawaji, Hideya; Keliet, Aminah; Kerhornou, Arnaud; Kim, Sunghoon; Kinsella, Rhoda; Klopp, Christophe; Kong, Lei; Lawson, Daniel; Lazarevic, Dejan; Lee, Ji-Hyun; Letellier, Thomas; Li, Chuan-Yun; Lio, Pietro; Liu, Chu-Jun; Luo, Jie; Maass, Alejandro; Mariette, Jerome; Maurel, Thomas; Merella, Stefania; Mohamed, Azza Mostafa; Moreews, Francois; Nabihoudine, Ibounyamine; Ndegwa, Nelson; Noirot, Céline; Perez-Llamas, Cristian; Primig, Michael; Quattrone, Alessandro; Quesneville, Hadi; Rambaldi, Davide; Reecy, James; Riba, Michela; Rosanoff, Steven; Saddiq, Amna Ali; Salas, Elisa; Sallou, Olivier; Shepherd, Rebecca; Simon, Reinhard; Sperling, Linda; Spooner, William; Staines, Daniel M; Steinbach, Delphine; Stone, Kevin; Stupka, Elia; Teague, Jon W; Dayem Ullah, Abu Z; Wang, Jun; Ware, Doreen; Wong-Erasmus, Marie; Youens-Clark, Ken; Zadissa, Amonida; Zhang, Shi-Jian; Kasprzyk, Arek

    2015-07-01

    The BioMart Community Portal (www.biomart.org) is a community-driven effort to provide a unified interface to biomedical databases that are distributed worldwide. The portal provides access to numerous database projects supported by 30 scientific organizations. It includes over 800 different biological datasets spanning genomics, proteomics, model organisms, cancer data, ontology information and more. All resources available through the portal are independently administered and funded by their host organizations. The BioMart data federation technology provides a unified interface to all the available data. The latest version of the portal comes with many new databases that have been created by our ever-growing community. It also comes with better support and extensibility for data analysis and visualization tools. A new addition to our toolbox, the enrichment analysis tool is now accessible through graphical and web service interface. The BioMart community portal averages over one million requests per day. Building on this level of service and the wealth of information that has become available, the BioMart Community Portal has introduced a new, more scalable and cheaper alternative to the large data stores maintained by specialized organizations. PMID:25897122

  19. The BioMart community portal: an innovative alternative to large, centralized data repositories

    PubMed Central

    Smedley, Damian; Haider, Syed; Durinck, Steffen; Pandini, Luca; Provero, Paolo; Allen, James; Arnaiz, Olivier; Awedh, Mohammad Hamza; Baldock, Richard; Barbiera, Giulia; Bardou, Philippe; Beck, Tim; Blake, Andrew; Bonierbale, Merideth; Brookes, Anthony J.; Bucci, Gabriele; Buetti, Iwan; Burge, Sarah; Cabau, Cédric; Carlson, Joseph W.; Chelala, Claude; Chrysostomou, Charalambos; Cittaro, Davide; Collin, Olivier; Cordova, Raul; Cutts, Rosalind J.; Dassi, Erik; Genova, Alex Di; Djari, Anis; Esposito, Anthony; Estrella, Heather; Eyras, Eduardo; Fernandez-Banet, Julio; Forbes, Simon; Free, Robert C.; Fujisawa, Takatomo; Gadaleta, Emanuela; Garcia-Manteiga, Jose M.; Goodstein, David; Gray, Kristian; Guerra-Assunção, José Afonso; Haggarty, Bernard; Han, Dong-Jin; Han, Byung Woo; Harris, Todd; Harshbarger, Jayson; Hastings, Robert K.; Hayes, Richard D.; Hoede, Claire; Hu, Shen; Hu, Zhi-Liang; Hutchins, Lucie; Kan, Zhengyan; Kawaji, Hideya; Keliet, Aminah; Kerhornou, Arnaud; Kim, Sunghoon; Kinsella, Rhoda; Klopp, Christophe; Kong, Lei; Lawson, Daniel; Lazarevic, Dejan; Lee, Ji-Hyun; Letellier, Thomas; Li, Chuan-Yun; Lio, Pietro; Liu, Chu-Jun; Luo, Jie; Maass, Alejandro; Mariette, Jerome; Maurel, Thomas; Merella, Stefania; Mohamed, Azza Mostafa; Moreews, Francois; Nabihoudine, Ibounyamine; Ndegwa, Nelson; Noirot, Céline; Perez-Llamas, Cristian; Primig, Michael; Quattrone, Alessandro; Quesneville, Hadi; Rambaldi, Davide; Reecy, James; Riba, Michela; Rosanoff, Steven; Saddiq, Amna Ali; Salas, Elisa; Sallou, Olivier; Shepherd, Rebecca; Simon, Reinhard; Sperling, Linda; Spooner, William; Staines, Daniel M.; Steinbach, Delphine; Stone, Kevin; Stupka, Elia; Teague, Jon W.; Dayem Ullah, Abu Z.; Wang, Jun; Ware, Doreen; Wong-Erasmus, Marie; Youens-Clark, Ken; Zadissa, Amonida; Zhang, Shi-Jian; Kasprzyk, Arek

    2015-01-01

    The BioMart Community Portal (www.biomart.org) is a community-driven effort to provide a unified interface to biomedical databases that are distributed worldwide. The portal provides access to numerous database projects supported by 30 scientific organizations. It includes over 800 different biological datasets spanning genomics, proteomics, model organisms, cancer data, ontology information and more. All resources available through the portal are independently administered and funded by their host organizations. The BioMart data federation technology provides a unified interface to all the available data. The latest version of the portal comes with many new databases that have been created by our ever-growing community. It also comes with better support and extensibility for data analysis and visualization tools. A new addition to our toolbox, the enrichment analysis tool is now accessible through graphical and web service interface. The BioMart community portal averages over one million requests per day. Building on this level of service and the wealth of information that has become available, the BioMart Community Portal has introduced a new, more scalable and cheaper alternative to the large data stores maintained by specialized organizations. PMID:25897122

  20. Development of Distributed System for Informational Location and Control on the Corporate Web Portal "Analytical Chemistry in Russia"

    NASA Astrophysics Data System (ADS)

    Shirokova, V. I.; Kolotov, V. P.; Alenina, M. V.

    A new Internet portal developed by community of Russian analysts has been launched in 2001 (http://www.geokhi.ru/~rusanalytchem, http://www.rusanalytchem.org) Corporate Web Portal information, "Analytical Chemistry in Russia" , Corporate Web Portal information, "Analytical Chemistry in Russia" ). Now the portal contains a large amount of information, great part of it is stored in the form of SQL data base (MS SQL). The information retrieval is made by means of ASP pages, containing VB Scripts. The obtained experience of work with such topical portal has detected some weak points, related with its centralized administration and updating. It has been found that urgent supporting of all requests from different persons/organizations on information allocation on the portal's server takes a lot of efforts and time. That is why, the further development of portal we relate with development of a distributed system for information allocation and control, under preserving of centralized administration for ensuring of security and stable working of the portal. Analysis and testing of some available technologies lead us to conclusion to apply MS Share Point technologies. A MS Share Point Team Services (SPTS) has been selected as a technology supporting relatively small groups, where MS SQL is used for storage data and metadata. The last feature was considered as decisive one for SPTS selection, allowing easy integration with data base of the whole portal. SPTS was launched as an independent Internet site accessible from home page of the portal. It serves as a root site to exit to dozens of subsites serving different bodies of Russian Scientific Council on analytical chemistry and external organizations located over the whole Russia. The secure functioning of such hierarchical system, which includes a lot of remote information suppliers, based on use of roles to manage user rights

  1. The CPTAC Data Portal: A Resource for Cancer Proteomics Research.

    PubMed

    Edwards, Nathan J; Oberti, Mauricio; Thangudu, Ratna R; Cai, Shuang; McGarvey, Peter B; Jacob, Shine; Madhavan, Subha; Ketchum, Karen A

    2015-06-01

    The Clinical Proteomic Tumor Analysis Consortium (CPTAC), under the auspices of the National Cancer Institute's Office of Cancer Clinical Proteomics Research, is a comprehensive and coordinated effort to accelerate the understanding of the molecular basis of cancer through the application of proteomic technologies and workflows to clinical tumor samples with characterized genomic and transcript profiles. The consortium analyzes cancer biospecimens using mass spectrometry, identifying and quantifying the constituent proteins and characterizing each tumor sample's proteome. Mass spectrometry enables highly specific identification of proteins and their isoforms, accurate relative quantitation of protein abundance in contrasting biospecimens, and localization of post-translational protein modifications, such as phosphorylation, on a protein's sequence. The combination of proteomics, transcriptomics, and genomics data from the same clinical tumor samples provides an unprecedented opportunity for tumor proteogenomics. The CPTAC Data Portal is the centralized data repository for the dissemination of proteomic data collected by Proteome Characterization Centers (PCCs) in the consortium. The portal currently hosts 6.3 TB of data and includes proteomic investigations of breast, colorectal, and ovarian tumor tissues from The Cancer Genome Atlas (TCGA). The data collected by the consortium is made freely available to the public through the data portal. PMID:25873244

  2. A web portal for in-silico action potential predictions

    PubMed Central

    Williams, Geoff; Mirams, Gary R.

    2015-01-01

    Introduction Multiple cardiac ion channels are prone to block by pharmaceutical compounds, and this can have large implications for cardiac safety. The effect of a compound on individual ion currents can now be measured in automated patch clamp screening assays. In-silico action potential models are proposed as one way of predicting the integrated compound effects on whole-cell electrophysiology, to provide an improved indication of pro-arrhythmic risk. Methods We have developed open source software to run cardiac electrophysiology simulations to predict the overall effect of compounds that block IKr, ICaL, INa, IKs, IK1 and Ito to varying degrees, using a choice of mathematical electrophysiology models. To enable safety pharmacology teams to run and evaluate these simulations easily, we have also developed an open source web portal interface to this simulator. Results The web portal can be found at https://chaste.cs.ox.ac.uk/ActionPotential. Users can enter details of compound affinities for ion channels in the form of IC50 or pIC50 values, run simulations, store the results for later retrieval, view summary graphs of the results, and export data to a spreadsheet format. Discussion This web portal provides a simple interface to reference versions of mathematical models, and well-tested state-of-the-art equation solvers. It provides safety teams easy access to the emerging technology of cardiac electrophysiology simulations for use in the drug-discovery process. PMID:25963830

  3. Variceal bleeding and portal hypertension: new lights on old horizon.

    PubMed

    Bhasin, D K; Siyad, I

    2004-02-01

    New clinical, endoscopic, and imaging modalities for diagnosing varices and predicting bleeding are being investigated. Transnasal endoscopy and ultrathin battery-powered esophagoscopes are being used to improve patient comfort and compliance. Patients who respond to portal pressure-reducing drugs not only have a reduced risk of bleeding, but also a reduced risk of developing other complications, with improved survival. Nitrates have been shown to have no definite role in primary prophylaxis against variceal bleeding. The hemodynamic response to treatment has an independent prognostic value for the risk of variceal bleeding. Newer drugs have been investigated for reducing the hepatic venous pressure gradient, but with little success. Survival after bleeding has increased due to improved patient care and technological advances. Combined radiographic and endoscopic management of gastric varices is evolving and appears to be promising. Nonvariceal bleeding from portal hypertensive gastropathy is increasingly being recognized as a potential cause of bleeding in patients with portal hypertension, and pharmacotherapy with octreotide appears to be promising for the treatment of this condition. Variceal band ligation in children has been found to be as safe and effective as in adults. PMID:14765309

  4. The Portal to the Universe an IYA2009 Cornerstone Project

    NASA Astrophysics Data System (ADS)

    Lindberg Christensen, Lars; Gay, P.; IYA2009 TPTTU Cornerstone Task Group

    2008-05-01

    The science of astronomy is extremely fast moving, and delivers new results on a daily basis, often in the form of spectacular news, images of forms and shapes not seen anywhere else, enhanced by illustrations and animations. Public astronomy communication has to develop apace with the other players in the mass market for electronic information such as the gaming and entertainment industries. The problem today is not so much the availability of excellent astronomy multimedia resources for use in education, outreach and the like, but rather finding and accessing these materials. The Portal to the Universe (TPTTU) seeks to fix this problem. The Portal to the Universe (TPTTU) is an IYA2009 Cornerstone project that will feature a comprehensive directory of observatories, facilities, astronomical societies, amateur astronomy societies, space artists, science communication universities, as well as news-, image-, event- and video- aggregators and Web 2.0 collaborative tools for astronomy multimedia community interaction. The Portal will enable innovative access to, and vastly multiply the use of, astronomy multimedia resources - including news, images, videos, events, podcasts, vodcasts etc. as a selective aggregator with a non-painful editorial mechanism in place. This talk will discuss the plans for the TPTTU content as well as the technology and editorial choices behind the scenes.

  5. BSD Portals for LINUX 2.0

    NASA Technical Reports Server (NTRS)

    McNab, A. David; woo, Alex (Technical Monitor)

    1999-01-01

    Portals, an experimental feature of 4.4BSD, extend the file system name space by exporting certain open () requests to a user-space daemon. A portal daemon is mounted into the file name space as if it were a standard file system. When the kernel resolves a pathname and encounters a portal mount point, the remainder of the path is passed to the portal daemon. Depending on the portal "pathname" and the daemon's configuration, some type of open (2) is performed. The resulting file descriptor is passed back to the kernel which eventually returns it to the user, to whom it appears that a "normal" open has occurred. A proxy portalfs file system is responsible for kernel interaction with the daemon. The overall effect is that the portal daemon performs an open (2) on behalf of the kernel, possibly hiding substantial complexity from the calling process. One particularly useful application is implementing a connection service that allows simple scripts to open network sockets. This paper describes the implementation of portals for LINUX 2.0.

  6. Higgs portals to pulsar collapse

    NASA Astrophysics Data System (ADS)

    Bramante, Joseph; Elahi, Fatemeh

    2015-06-01

    Pulsars apparently missing from the Galactic center could have been destroyed by asymmetric fermionic dark matter (mX=1 - 100 GeV ) coupled to a light scalar (mϕ=5 - 20 MeV ), which mixes with the Higgs boson. We point out that this pulsar-collapsing dark sector can resolve the core-cusp problem and will either be excluded or discovered by upcoming direct detection experiments. Another implication is a maximum pulsar age curve that increases with distance from the Galactic center, with a normalization that depends on the couplings and masses of dark sector particles. In addition, we use old pulsars outside the Galactic center to place bounds on asymmetric Higgs portal models.

  7. Freeze-in through portals

    SciTech Connect

    Blennow, Mattias; Fernandez-Martínez, Enrique; Zaldívar, Bryan E-mail: enrique.fernandez-martinez@uam.es

    2014-01-01

    The popular freeze-out paradigm for Dark Matter (DM) production, relies on DM-baryon couplings of the order of the weak interactions. However, different search strategies for DM have failed to provide a conclusive evidence of such (non-gravitational) interactions, while greatly reducing the parameter space of many representative models. This motivates the study of alternative mechanisms for DM genesis. In the freeze-in framework, the DM is slowly populated from the thermal bath while never reaching equilibrium. In this work, we analyse in detail the possibility of producing a frozen-in DM via a mediator particle which acts as a portal. We give analytical estimates of different freeze-in regimes and support them with full numerical analyses, taking into account the proper distribution functions of bath particles. Finally, we constrain the parameter space of generic models by requiring agreement with DM relic abundance observations.

  8. The Astrostatistics and Astroinformatics Portal

    NASA Astrophysics Data System (ADS)

    Feigelson, Eric; Hilbe, J. M.

    2014-01-01

    The Astrostatistics and Astroinformatics Portal (ASAIP, http://asaip.psu.edu) is a Web resource started in 2012 to foster research into advanced methodologies for astronomical research, and to promulgate such methods into the broader astronomy community. It provides searchable abstracts to Recent Papers in the field, several discussion Forums, various resources for researchers, brief Articles by experts, lists of Meetings, and access to various Web resources such as on-line courses, books and blogs. The material can be electronically searched. The site will be used for public outreach by organizations associated with the AAS, IAU, ISI (International Statistical Institute), and LSST. ASAIP has nearly 700 members who can contribute material, and its resources are readable by the general Web public. This presentation gives examples of recent ASAIP entries and encourages AAS members to use its resources.

  9. Zolmitriptan: A Novel Portal Hypotensive Agent Which Synergizes with Propranolol in Lowering Portal Pressure

    PubMed Central

    Reboredo, Mercedes; Chang, Haisul C. Y.; Barbero, Roberto; Rodríguez-Ortigosa, Carlos M.; Pérez-Vizcaíno, Francisco; Morán, Asunción; García, Mónica; Banales, Jesús M.; Carreño, Norberto; Alegre, Félix; Herrero, Ignacio; Quiroga, Jorge

    2013-01-01

    Objective Only a limited proportion of patients needing pharmacological control of portal hypertension are hemodynamic responders to propranolol. Here we analyzed the effects of zolmitriptan on portal pressure and its potential interaction with propranolol. Methods Zolmitriptan, propranolol or both were tested in two rat models of portal hypertension: common bile duct ligation (CBDL) and CCl4-induced cirrhosis. In these animals we measured different hemodynamic parameters including portal venous pressure, arterial renal flow, portal blood flow and cardiac output. We also studied the changes in superior mesenteric artery perfusion pressure and in arterial wall cAMP levels induced by zolmitriptan, propranolol or both. Moreover, we determined the effect of splanchnic sympathectomy on the response of PVP to zolmitriptan. Results In both models of portal hypertension zolmitriptan induced a dose-dependent transient descent of portal pressure accompanied by reduction of portal flow with only slight decrease in renal flow. In cirrhotic rats, splanchnic sympathectomy intensified and prolonged zolmitriptan-induced portal pressure descent. Also, propranolol caused more intense and durable portal pressure fall when combined with zolmitriptan. Mesenteric artery perfusion pressure peaked for about 1 min upon zolmitriptan administration but showed no change with propranolol. However propranolol enhanced and prolonged the elevation in mesenteric artery perfusion pressure induced by zolmitriptan. In vitro studies showed that propranolol prevented the inhibitory effects of β2-agonists on zolmitriptan-induced vasoconstriction and the combination of propranolol and zolmitriptan significantly reduced the elevation of cAMP caused by β2-agonists. Conclusion Zolmitriptan reduces portal hypertension and non-selective beta-blockers can improve this effect. Combination therapy deserves consideration for patients with portal hypertension failing to respond to non-selective beta

  10. [Idiopathic non-cirrhotic portal hypertension: An update].

    PubMed

    Bissonnette, Julien; Rautou, Pierre-Emmanuel; Valla, Dominique-Charles

    2015-10-01

    Idiopathic non-cirrhotic portal hypertension is an under-estimated cause of portal hypertension. The diagnosis requires the exclusion of cirrhosis, common causes of chronic liver disease and venous obstruction of the portal and hepatic veins. It has been associated with various extra-hepatic conditions that are most frequently immunologic, prothrombotic, hematologic and toxic. The most frequent clinical complications are variceal hemorrhage and portal vein thrombosis. Complications of portal hypertension should be managed as in patients with cirrhosis. PMID:26362514

  11. Developing a Web 2.0 telemedical education system: the AJAX-Cocoon portal.

    PubMed

    Mohammed, S; Orabi, A; Fiaidhi, J; Orabi, M

    2008-01-01

    Web 2.0 technologies such as wikis, podcasts/vodcasting, blogs and semantic portals could be quite effective tools in e-learning for health professionals. If effectively deployed, such tools can offer a way to enhance students', clinicians' and patients' learning experiences, and deepens levels of learners' engagement and collaboration within medical learning environments. However, Web 2.0 requires simplicity of use as well as integration with modern web technologies. This article presents a Web 2.0 telemedical portal, which provides a social community-learning paradigm from the desk of the physician, the student, the hospital administrator, or the insurer. The presented portal utilises RESTful web services and techniques like content syndication, mushups and Asynchronous JavaScript API and XML (AJAX). The designed portal is based on the Apache Cocoon RESTful framework for sharing Digital Imaging and Communications in Medicine (DICOM) medical case studies. Central to this article is the integration between Cocoon and AJAX. The proposed AJAX-Cocoon portal utilises a JSP portlet architecture, which manages the interaction dynamics and overcomes the shortcomings of the JSR 168 and WSRP 1.0 standards. PMID:18583294

  12. Promoting scientific collaboration and research through integrated social networking capabilities within the OpenTopography Portal

    NASA Astrophysics Data System (ADS)

    Nandigam, V.; Crosby, C. J.; Baru, C.

    2009-04-01

    LiDAR (Light Distance And Ranging) topography data offer earth scientists the opportunity to study the earth's surface at very high resolutions. As a result, the popularity of these data is growing dramatically. However, the management, distribution, and analysis of community LiDAR data sets is a challenge due to their massive size (multi-billion point, mutli-terabyte). We have also found that many earth science users of these data sets lack the computing resources and expertise required to process these data. We have developed the OpenTopography Portal to democratize access to these large and computationally challenging data sets. The OpenTopography Portal uses cyberinfrastructure technology developed by the GEON project to provide access to LiDAR data in a variety of formats. LiDAR data products available range from simple Google Earth visualizations of LiDAR-derived hillshades to 1 km2 tiles of standard digital elevation model (DEM) products as well as LiDAR point cloud data and user generated custom-DEMs. We have found that the wide spectrum of LiDAR users have variable scientific applications, computing resources and technical experience and thus require a data system with multiple distribution mechanisms and platforms to serve a broader range of user communities. Because the volume of LiDAR topography data available is rapidly expanding, and data analysis techniques are evolving, there is a need for the user community to be able to communicate and interact to share knowledge and experiences. To address this need, the OpenTopography Portal enables social networking capabilities through a variety of collaboration tools, web 2.0 technologies and customized usage pattern tracking. Fundamentally, these tools offer users the ability to communicate, to access and share documents, participate in discussions, and to keep up to date on upcoming events and emerging technologies. The OpenTopography portal achieves the social networking capabilities by integrating various

  13. [Association of biliary calculosis and portal cavernomatosis].

    PubMed

    Crespi, C; De Giorgio, A M

    1992-08-01

    This paper reports the case of a woman, who underwent surgery because of cholelithiasis, with intraoperative finding of prehepatic portal hypertension from portal vein thrombosis ("portal cavernoma") with healthy liver, later confirmed by angiographic studies. This rare pathologic association carries a higher risk of major operative complications; therefore the Authors agree with the general belief that, for these cases, biliary tract surgery should be as simple and safe as possible. In the case of preoperative diagnosis of biliary disease associated with portal cavernoma, should a surgical approach on the biliary tract be required, we agree on the advisability of performing a shunting procedure before any kind of biliary surgery. In case of variceal bleeding endoscopic sclerotherapy will be the first choice; surgical procedures (shunting) should be seen as a second choice in case of rebleeding after sclerotherapy. PMID:1407632

  14. 23. INCLINED END POST / VERTICAL / DIAGONAL / PORTAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. INCLINED END POST / VERTICAL / DIAGONAL / PORTAL BRACING DETAIL. VIEW TO SOUTHEAST. - Abraham Lincoln Memorial Bridge, Spanning Missouri River on Highway 30 between Nebraska & Iowa, Blair, Washington County, NE

  15. The Fukushima Daiichi Accident Study Information Portal

    SciTech Connect

    Shawn St. Germain; Curtis Smith; David Schwieder; Cherie Phelan

    2012-11-01

    This paper presents a description of The Fukushima Daiichi Accident Study Information Portal. The Information Portal was created by the Idaho National Laboratory as part of joint NRC and DOE project to assess the severe accident modeling capability of the MELCOR analysis code. The Fukushima Daiichi Accident Study Information Portal was created to collect, store, retrieve and validate information and data for use in reconstructing the Fukushima Daiichi accident. In addition to supporting the MELCOR simulations, the Portal will be the main DOE repository for all data, studies and reports related to the accident at the Fukushima Daiichi nuclear power station. The data is stored in a secured (password protected and encrypted) repository that is searchable and accessible to researchers at diverse locations.

  16. Modeling and analysis of web portals performance

    NASA Astrophysics Data System (ADS)

    Abdul Rahim, Rahela; Ibrahim, Haslinda; Syed Yahaya, Sharipah Soaad; Khalid, Khairini

    2011-10-01

    The main objective of this study is to develop a model based on queuing theory at a system level of web portals performance for a university. A system level performance model views the system being modeled as a 'black box' which considers the arrival rate of packets to the portals server and service rate of the portals server. These two parameters are important elements to measure Web portals performance metrics such as server utilization, average server throughput, average number of packet in the server and mean response time. This study refers to infinite population and finite queue. The proposed analytical model is simple in such a way that it is easy to define and fast to interpret the results but still represents the real situation.

  17. Idiopathic Noncirrhotic Portal Hypertension: An Appraisal

    PubMed Central

    Lee, Hwajeong; Rehman, Aseeb Ur; Fiel, M. Isabel

    2016-01-01

    Idiopathic noncirrhotic portal hypertension is a poorly defined clinical condition of unknown etiology. Patients present with signs and symptoms of portal hypertension without evidence of cirrhosis. The disease course appears to be indolent and benign with an overall better outcome than cirrhosis, as long as the complications of portal hypertension are properly managed. This condition has been recognized in different parts of the world in diverse ethnic groups with variable risk factors, resulting in numerous terminologies and lack of standardized diagnostic criteria. Therefore, although the diagnosis of idiopathic noncirrhotic portal hypertension requires clinical exclusion of other conditions that can cause portal hypertension and histopathologic confirmation, this entity is under-recognized clinically as well as pathologically. Recent studies have demonstrated that variable histopathologic entities with different terms likely represent a histologic spectrum of a single entity of which obliterative portal venopathy might be an underlying pathogenesis. This perception calls for standardization of the nomenclature and formulation of widely accepted diagnostic criteria, which will facilitate easier recognition of this disorder and will highlight awareness of this entity. PMID:26563701

  18. The Gulf of Mexico Coastal Ocean Observing System: A Gulf Science Portal

    NASA Astrophysics Data System (ADS)

    Howard, M.; Gayanilo, F.; Kobara, S.; Jochens, A. E.

    2013-12-01

    The Gulf of Mexico Coastal Ocean Observing System's (GCOOS) regional science portal (gcoos.org) was designed to aggregate data and model output from distributed providers and to offer these, and derived products, through a single access point in standardized ways to a diverse set of users. The portal evolved under the NOAA-led U.S. Integrated Ocean Observing System (IOOS) program where automated largely-unattended machine-to-machine interoperability has always been a guiding tenet for system design. The web portal has a business unit where membership lists, new items, and reference materials are kept, a data portal where near real-time and historical data are held and served, and a products portal where data are fused into products tailored for specific or general stakeholder groups. The staff includes a system architect who built and maintains the data portal, a GIS expert who built and maintains the current product portal, the executive director who marshals resources to keep news items fresh and data manger who manages most of this. The business portal is built using WordPress which was selected because it appeared to be the easiest content management system for non-web programmers to add content to, maintain and enhance. The data portal is custom built and uses database, PHP, and web services based on Open Geospatial Consortium standards-based Sensor Observation Service (SOS) with Observations and Measurements (O&M) encodings. We employ a standards-based vocabulary, which we helped develop, which is registered at the Marine Metadata Interoperability Ontology Registry and Repository (http://mmisw.org). The registry is currently maintained by one of the authors. Products appearing in the products portal are primarily constructed using ESRI software by a Ph.D. level Geographer. Some products were built with other software, generally by graduate students over the years. We have been sensitive to the private sector when deciding which products to produce. While

  19. Electronic Health Record Patient Portal Adoption by Health Care Consumers: An Acceptance Model and Survey

    PubMed Central

    2016-01-01

    Background The future of health care delivery is becoming more citizen centered, as today’s user is more active, better informed, and more demanding. Worldwide governments are promoting online health services, such as electronic health record (EHR) patient portals and, as a result, the deployment and use of these services. Overall, this makes the adoption of patient-accessible EHR portals an important field to study and understand. Objective The aim of this study is to understand the factors that drive individuals to adopt EHR portals. Methods We applied a new adoption model using, as a starting point, Ventkatesh's Unified Theory of Acceptance and Use of Technology in a consumer context (UTAUT2) by integrating a new construct specific to health care, a new moderator, and new relationships. To test the research model, we used the partial least squares (PLS) causal modelling approach. An online questionnaire was administrated. We collected 360 valid responses. Results The statistically significant drivers of behavioral intention are performance expectancy (beta=.200; t=3.619), effort expectancy (beta=.185; t=2.907), habit (beta=.388; t=7.320), and self-perception (beta=.098; t=2.285). The predictors of use behavior are habit (beta=0.206; t=2.752) and behavioral intention (beta=0.258; t=4.036). The model explained 49.7% of the variance in behavioral intention and 26.8% of the variance in use behavior. Conclusions Our research helps to understand the desired technology characteristics of EHR portals. By testing an information technology acceptance model, we are able to determine what is more valued by patients when it comes to deciding whether to adopt EHR portals or not. The inclusion of specific constructs and relationships related to the health care consumer area also had a significant impact on understanding the adoption of EHR portals. PMID:26935646

  20. A new ICPP portal monitor

    NASA Astrophysics Data System (ADS)

    Georgeson, M. A.; Nichols, C. E.

    1981-04-01

    Low levels of beta and/or gamma contamination as well as gram quantities of special nuclear materials can be detected by a portal-mounted monitor even though the monitor is located in the presence of varying background levels of radiation. The detector consists of 14 area-wide gas proportional detectors, an occupancy monitor, an electronic system for signal and alarm logic, and support hardware. Each of the 14-15.3 and 35.6 cm propane purged detectors has a two to five mg/sq cm mylar cover and each detector has a total sensitive area of 450 sq cm. Six separate signal alarm and logic channels detect the presence of radioactivity and indicate whether the radiation is coming from the head, top right body, top left body, lower right body, lower left body, or the feet area, making it easier to locate the source and minimize personnel delay. The swinging door design of the monitor is such that anyone passing through must come into close proximity of the detectors and is slowed enough to allow for a meaningful scan without causing inordinate delays.

  1. Photonic dark matter portal revisited

    NASA Astrophysics Data System (ADS)

    Alavi, S. A.; Kazemian, F. S.

    2016-05-01

    In our previous paper, we studied a model of dark matter (DM) in which the hidden sector interacts with standard model particles via a hidden photonic portal (HP). We investigated the effects of this new interaction on the hydrogen atom and obtained an upper bound for the coupling of the model as f ≤ 10-12. In this work, we study the effects of HP on two interesting exotic atoms namely muonium and positronium. We obtain a tighter upper limit on the coupling as f ≤ 10-13. We also calculate the change (shift) in the Aharonov-Bohm phase due to HP and find that the phase shift is negligibly small (for DM particles mass in the GeV range). Recently a 3.5 keV X-ray line signal observed in the spectrum of 73 galaxy clusters, reported by the XXM-Newton X-ray observatory. Since in HP model the DM particles can decay directly into photons, so we finally calculate the value of the coupling constant f using the condition ΔEDM = 3.5 keV.

  2. Examining the Influence of Personality Traits on Intranet Portal Adoption by Faculty in Higher Education

    ERIC Educational Resources Information Center

    Shambare, Narcissus

    2013-01-01

    The problem examined in the proposed study was the underutilization of the intranet portals (IP) by faculty in institutions of higher education (IHE). Despite the time and investment allocated to the IP, the technology remains underutilized to improve productivity, efficiency, and justify its investment yet there is lack of understanding of why…

  3. Autism Post-Mortem Neuroinformatic Resource: The Autism Tissue Program (ATP) Informatics Portal

    ERIC Educational Resources Information Center

    Brimacombe, Michael B.; Pickett, Richard; Pickett, Jane

    2007-01-01

    The Autism Tissue Program (ATP) was established to oversee and manage brain donations related to neurological research in autism. The ATP Informatics Portal (www.atpportal.org) is an integrated data access system based on Oracle technology, developed to provide access for researchers to information on this rare tissue resource. It also permits…

  4. Interest in the Use of Computerized Patient Portals: Role of the Provider–Patient Relationship

    PubMed Central

    Hess, Rachel; Bryce, Cindy L.; McTigue, Kathleen; Olshansky, Ellen; Fitzgerald, Katharine; Fischer, Gary S.

    2007-01-01

    Background Bioinformatics experts are developing interactive patient portals to help those living with diabetes and other chronic diseases to better manage their conditions. However, little is known about what influences patients’ desires to use this technology. Objective To discern the impact of the provider–patient relationship on interest in using a web-based patient portal. Design Qualitative analysis of focus groups. Participants Ten focus groups involving 39 patients (range 2–7) recruited from four primary care practices. Approach A qualitative approach was used, which involved reading transcribed texts until a consensus was reached on data interpretation. An intercoder reliability kappa score (0.89) was determined by comparing the provider–patient relationship talk selected by the two coders. A conceptual framework was developed, which involved the development and refinement of a codebook and the application of it to the transcripts. Results Interest in the portal was linked to dissatisfaction with the provider–patient relationship, including dissatisfaction with provider communication/responsiveness, the inability to obtain medical information, and logistical problems with the office. Disinterest in the portal was linked to satisfaction with the provider–patient relationship, including provider communication/responsiveness, difficulty in using the portal, and fear of losing relationships and e-mail contact with the provider. No patient identified encrypted e-mail communication through the portal as an advantage. Conclusions Promoting the use of computerized portals requires patient-based adaptations. These should include ease of use, direct provider e-mail, and reassurances that access and interpersonal relationships will not be lost. Education is needed about privacy concerns regarding traditional e-mail communication. PMID:18095039

  5. Anterolateral Portal Is Less Painful than Superolateral Portal in Knee Intra-Articular Injection

    PubMed Central

    Lee, Sung Yup; GN, Kiran Kumar; Chung, Byung June; Lee, Sang Wook

    2015-01-01

    Purpose Intra-articular knee injections are commonly performed in clinical practice for treating various knee joint disorders such as osteoarthritis and rheumatoid arthritis. When selecting the portal for injection, not only intra-articular needle accuracy but also procedural pain should be taken into consideration. The purpose of this study was to determine whether injection through anterolateral portal provokes less pain and provides better pain relief compared to superolateral portal. Materials and Methods A total of 60 patients with primary osteoarthritis of the knee receiving intra-articular injections were randomized into 2 groups according to the type of portal approach; anterolateral or superolateral. All patients received hyaluronic acid (20 mg) and triamcinolone (40 mg) as the first injection followed by second and third injections of hyaluronic acid on a weekly basis. Underlying knee pain, procedural pain, and knee pain at 4 weeks were evaluated using visual analogue scale (VAS). Results Injection through anterolateral portal provoked less pain (VAS, 1.5±1.3) than the superolateral portal (VAS, 1.5 vs. 2.7; p=0.004). No differences were found in the degree of pain relief at weeks between the two groups (p=0.517). Conclusions We recommend the use of anterolateral portal for intra-articular knee injection as it provokes less pain and comparably short-term pain relief than the superolateral portal. PMID:26676089

  6. The Sydney West Knowledge Portal: Evaluating the Growth of a Knowledge Portal to Support Translational Research

    PubMed Central

    2016-01-01

    Background The Sydney West Translational Cancer Research Centre is an organization funded to build capacity for translational research in cancer. Translational research is essential for ensuring the integration of best available evidence into practice and for improving patient outcomes. However, there is a low level of awareness regarding what it is and how to conduct it optimally. One solution to addressing this gap is the design and deployment of web-based knowledge portals to disseminate new knowledge and engage with and connect dispersed networks of researchers. A knowledge portal is an web-based platform for increasing knowledge dissemination and management in a specialized area. Objective To measure the design and growth of an web-based knowledge portal for increasing individual awareness of translational research and to build organizational capacity for the delivery of translational research projects in cancer. Methods An adaptive methodology was used to capture the design and growth of an web-based knowledge portal in cancer. This involved stakeholder consultations to inform initial design of the portal. Once the portal was live, site analytics were reviewed to evaluate member usage of the portal and to measure growth in membership. Results Knowledge portal membership grew consistently for the first 18 months after deployment, before leveling out. Analysis of site metrics revealed members were most likely to visit portal pages with community-generated content, particularly pages with a focus on translational research. This was closely followed by pages that disseminated educational material about translational research. Conclusions Preliminary data from this study suggest that knowledge portals may be beneficial tools for translating new evidence and fostering an environment of communication and collaboration. PMID:27357641

  7. Extending the Lunar Mapping and Modeling Portal - New Capabilities and New Worlds

    NASA Astrophysics Data System (ADS)

    Day, B.; Law, E.; Arevalo, E.; Bui, B.; Chang, G.; Dodge, K.; Kim, R.; Malhotra, S.; Sadaqathullah, S.; Schmidt, G.; Bailey, B.

    2015-10-01

    NASA's Lunar Mapping and Modeling Portal (LMMP) provides a web-based Portal and a suite of interactive visualization and analysis tools to enable mission planners, lunar scientists, and engineers to access mapped lunar data products from past and current lunar missions (http://lmmp.nasa.gov). During the past year, the capabilities and data served by LMMP have been significantly expanded. New interfaces are providing improved ways to access and visualize data. At the request of NASA's Science Mission Directorate, LMMP's technology and capabilities are now being extended to additional planetary bodies. New portals for Vesta and Mars are the first of these new products to be released. This presentation will provide an overview of LMMP, Vesta Trek, and Mars Trek, demonstrate their uses and capabilities, highlight new features, and preview coming enhancements.

  8. Extending the Lunar Mapping and Modeling Portal - New Capabilities and New Worlds

    NASA Technical Reports Server (NTRS)

    Day, B.; Law, E.; Arevalo, E.; Bui, B.; Chang, G.; Dodge, K.; Kim, R.; Malhotra, S.; Sadaqathullah, S.; Schmidt, G.; Bailey, B.

    2015-01-01

    NASA's Lunar Mapping and Modeling Portal (LMMP) provides a web-based Portal and a suite of interactive visualization and analysis tools to enable mission planners, lunar scientists, and engineers to access mapped lunar data products from past and current lunar missions (http://lmmp.nasa.gov). During the past year, the capabilities and data served by LMMP have been significantly expanded. New interfaces are providing improved ways to access and visualize data. At the request of NASA's Science Mission Directorate, LMMP's technology and capabilities are now being extended to additional planetary bodies. New portals for Vesta and Mars are the first of these new products to be released. This presentation will provide an overview of LMMP, Vesta Trek, and Mars Trek, demonstrate their uses and capabilities, highlight new features, and preview coming enhancements.

  9. HELI-DEM portal for geo-processing services

    NASA Astrophysics Data System (ADS)

    Cannata, Massimiliano; Antonovic, Milan; Molinari, Monia

    2014-05-01

    HELI-DEM (Helvetia-Italy Digital Elevation Model) is a project developed in the framework of Italy/Switzerland Operational Programme for Trans-frontier Cooperation 2007-2013 whose major aim is to create a unified digital terrain model that includes the alpine and sub-alpine areas between Italy and Switzerland. The partners of the project are: Lombardy Region, Piedmont Region, Polytechnic of Milan, Polytechnic of Turin and Fondazione Politecnico from Italy; Institute of Earth Sciences (SUPSI) from Switzerland. The digital terrain model has been produced by integrating and validating the different elevation data available for the areas of interest, characterized by different reference frame, resolutions and accuracies: DHM at 25 m resolution from Swisstopo, DTM at 20 m resolution from Lombardy Region, DTM at 5 m resolution from Piedmont Region and DTM LiDAR PST-A at about 1 m resolution, that covers the main river bed areas and is produced by the Italian Ministry of the Environment. Further results of the project are: the generation of a unique Italian Swiss geoid with an accuracy of few centimeters (Gilardoni et al. 2012); the establishment of a GNSS permanent network, prototype of a transnational positioning service; the development of a geo-portal, entirely based on open source technologies and open standards, which provides the cross-border DTM and offers some capabilities of analysis and processing through the Internet. With this talk, the authors want to present the main steps of the project with a focus on the HELI-DEM geo-portal development carried out by the Institute of Earth Sciences, which is the access point to the DTM outputted from the project. The portal, accessible at http://geoservice.ist.supsi.ch/helidem, is a demonstration of open source technologies combined for providing access to geospatial functionalities to wide non GIS expert public. In fact, the system is entirely developed using only Open Standards and Free and Open Source Software (FOSS

  10. Pancreatic Adenocarcinoma Complicated by Sinistral Portal Hypertension

    PubMed Central

    Kaley, Kristin; Lamb, Lynne

    2016-01-01

    Pancreatic cancer is known for vague symptoms that lead to a delay in diagnosis, and hence most cases are found at an advanced stage. Many complications can happen secondary to pancreatic cancer including diabetes, malabsorption, and deep venous thrombosis. Sinistral (segmental or left-sided) portal hypertension (SPH) refers to portal hypertension confined to the left-sided segment of the portal venous system namely the splenic side, and the most common etiology is splenic vein thrombosis (SVT). We present here a case of a 66-year-old male with advanced pancreatic cancer who died due to bleeding secondary to SVT. We advise physicians caring for these patients to be aware of this complication, which may also be the manifestation of an undiagnosed pancreatic cancer. PMID:27555987

  11. Spontaneous Resolution of Portal Vein Thrombosis

    PubMed Central

    Banumukala, Vishnu; Babu, Adarsh

    2008-01-01

    A 56-year-old male was admitted with symptoms of belching, abdominal pain and weight loss of 2 weeks duration. Examination revealed hepatosplenomegaly which was confirmed by computed tomography (CT). CT images also revealed filling defects in the portal vein and intrahepatic branches consistent with thrombosis and hepatosplenic infarcts. Alkaline phosphatase was elevated at 688 units, all other investigations, including full blood count, coagulation screen and tumour markers, were normal. Magnetic resonance cholangiopancreatography did not reveal any mass in the porta hepatis. Upper gastrointestinal endoscopy and colonoscopy were normal. Liver biopsy was normal and did not reveal any evidence of lymphoma. The raised alkaline phosphatase settled to reference range over a period of 3 weeks. Thrombophilia screen was negative. Contrast CT of the abdomen performed after 4 weeks displayed revascularisation of the previously thrombosed portal vein and intrahepatic branches. The patient has remained asymptomatic since and we note spontaneous recanalisation of the previously occluded portal vein. PMID:21490872

  12. Spontaneous resolution of portal vein thrombosis.

    PubMed

    Banumukala, Vishnu; Babu, Adarsh

    2008-01-01

    A 56-year-old male was admitted with symptoms of belching, abdominal pain and weight loss of 2 weeks duration. Examination revealed hepatosplenomegaly which was confirmed by computed tomography (CT). CT images also revealed filling defects in the portal vein and intrahepatic branches consistent with thrombosis and hepatosplenic infarcts. Alkaline phosphatase was elevated at 688 units, all other investigations, including full blood count, coagulation screen and tumour markers, were normal. Magnetic resonance cholangiopancreatography did not reveal any mass in the porta hepatis. Upper gastrointestinal endoscopy and colonoscopy were normal. Liver biopsy was normal and did not reveal any evidence of lymphoma. The raised alkaline phosphatase settled to reference range over a period of 3 weeks. Thrombophilia screen was negative. Contrast CT of the abdomen performed after 4 weeks displayed revascularisation of the previously thrombosed portal vein and intrahepatic branches. The patient has remained asymptomatic since and we note spontaneous recanalisation of the previously occluded portal vein. PMID:21490872

  13. Portal hypertension and ascites in extramedullary hematopoiesis.

    PubMed

    Amarapurkar, Pooja; Parekh, Sunil; Amarapurkar, Anjali; Amarapurkar, Deepak

    2012-06-01

    Myeloproliferative diseases (MPD) are clonal stem cell disorders which mainly include polycythemia vera (PV), essential thrombocythemia (ET), and idiopathic myelofibrosis (IMF). They are characterized by leucocytosis, thrombocytosis, erythrocytosis, splenomegaly, and bone marrow hypercellularity. This might also result in extramedullary hematopoiesis. Abdominal manifestation has been recognized as a feature of these disorders. Splenomegaly and hepatomegaly are fairly common as opposed to ascites which is rare. The MPDs mainly affect the hepatic circulatory systems. The common hepatic manifestations are Budd-Chiari syndrome (BCS), portal vein thrombosis (PVT), and nodular regenerative hyperplasia. A few other features seen in MPDs are caused by extramedullary hematopoiesis, increased hepatic blood flow, and secondary hemosiderosis from multiple blood transfusions. Portal hypertension is found in up to 7% of patients. We report a case of portal hypertension with ascites in a patient with extramedullary hematopoiesis treated with transjugular intrahepatic portocaval shunt (TIPS). PMID:25755427

  14. [Effect of dopamine on the portal pressure].

    PubMed

    Benko, H; Peschl, L; Schüller, J; Neumayr, A

    1975-01-01

    1. An infusion of 3 gamma/kg/min dopamine causes a significant increase in the renal plasma flow and the glomerulum filtration rate. This dosage does not cause a change of the mean systolic and arterial pressure. This effect may also be observed in patients with hepatic cirrhosis. 2. The wedged hepatic vein pressure, an indicator for the portal pressure, only shows a slight increase (9,46 +/- 9,41%) as compared to the initial pressure produced by the mentioned dose. Measurements of the spleen pulpa pressure, which likewise indicates the portal pressure, showed an increase of pressure up to 100% due to pressing or coughing. 3. If in the case of bleeding oesophageal varices acute renal failure might develop, the advantage of the effect of dopamine in stimulating the blood flow through the kidneys may be considered more important than the minute danger of a slight increase of the portal pressure, which might provoke haemorrhage. PMID:1220517

  15. NORTH PORTAL OF VIADUCT WHERE IT MERGES WITH AURORA AVENUE; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    NORTH PORTAL OF VIADUCT WHERE IT MERGES WITH AURORA AVENUE; DENNY PARK AT TOP MIDDLE OF PICTURE. TOP OF PORTAL INTERSECTS WITH SEVENTH AVENUE ON THE DIAGONAL. - Alaskan Way Viaduct and Battery Street Tunnel, Seattle, King County, WA

  16. 13. Detail, connection point of end post, top chord, portal ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Detail, connection point of end post, top chord, portal strut, and tension members at upstream side of west portal, view to northwest. - Dry Creek Bridge, Spanning Dry Creek at Cook Road, Ione, Amador County, CA

  17. 340. Caltrans, Photographer October 14, 1935 "TUNNEL WEST PORTAL"; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    340. Caltrans, Photographer October 14, 1935 "TUNNEL - WEST PORTAL"; VIEW OF TUNNEL - WEST PORTAL' UNDER CONSTRUCTION SHOWING EXCAVATION OF TUNNEL AFTER POUR. 5-1669 - San Francisco Oakland Bay Bridge, Spanning San Francisco Bay, San Francisco, San Francisco County, CA

  18. Ultrasonographic diagnosis of unusual portal vascular abnormalities in two cats.

    PubMed

    McConnell, J F; Sparkes, A H; Ladlow, J; Doust, R; Davies, S

    2006-06-01

    Two cases of ascites secondary to portal vascular abnormalities associated with portal hypertension are described. In the first case a five-month-old cat was presented with recurrent ascites and investigations showed that the underlying cause was a hepatic arteriovenous fistula. Ultrasonography showed direct communication of the coeliac artery and right branch of the portal vein. There was also hepatofugal flow in the main portal vein consistent with portal hypertension. The ultrasonographic features were similar to those seen in dogs with hepatic arteriovenous fistulae. In the second case, ascites, portal hypertension and an intraluminal mass in the main portal vein was diagnosed in a 16-year-old cat that had been presented with hyperthyroidism and hepatomegaly. Acquired portosystemic collaterals involving the left renal vein were present. Additional diagnostic investigations were not permitted. Ultrasonography was useful in both cases to document portal hypertension and the underlying cause. PMID:16761986

  19. 43. VIEW OF THE RAMP ABOVE LOWER PORTAL AND RAMP, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    43. VIEW OF THE RAMP ABOVE LOWER PORTAL AND RAMP, LOOKING NORTHWEST. THE RAMP WAS USED TO GUIDE RUN-OFF FROM THUNDERSTORMS AWAY FROM THE PORTAL. - Independent Coal & Coke Company, Kenilworth, Carbon County, UT

  20. Calibration method for spectroscopic systems

    DOEpatents

    Sandison, David R.

    1998-01-01

    Calibration spots of optically-characterized material placed in the field of view of a spectroscopic system allow calibration of the spectroscopic system. Response from the calibration spots is measured and used to calibrate for varying spectroscopic system operating parameters. The accurate calibration achieved allows quantitative spectroscopic analysis of responses taken at different times, different excitation conditions, and of different targets.

  1. Calibration method for spectroscopic systems

    DOEpatents

    Sandison, D.R.

    1998-11-17

    Calibration spots of optically-characterized material placed in the field of view of a spectroscopic system allow calibration of the spectroscopic system. Response from the calibration spots is measured and used to calibrate for varying spectroscopic system operating parameters. The accurate calibration achieved allows quantitative spectroscopic analysis of responses taken at different times, different excitation conditions, and of different targets. 3 figs.

  2. The CeDRES data portal

    NASA Astrophysics Data System (ADS)

    Albert-Aguilar, Alexandre; Delmotte, Pauline; André, François; Brissebrat, Guillaume; Canonici, Jean-Christophe; Piguet, Bruno

    2016-04-01

    SAFIRE is the French facility dedicated to airborne measurement for environmental research. The SAFIRE steering committee decided that access to its archives should be improved. If certain data, including recent campaigns, are available online, access to them is difficult for users because these data are dispersed in as many data portals as campaigns. Most of projects are not able to keep medium to long term online access to their database. Therefore, many airborne data, particularly the oldest, are not available online, stored on media whose sustainability is not guaranteed. SAFIRE also decided to identify old data stored in Meudon (France) on paper and hard media and to rescue with the help of an archivist. At the same time, the development of a centralized digital archive - containing data collected with the Fokker - 27 " ARAT " and Merlin IV aircraft - associated to a web portal was given to SEDOO. The first part of the project consisted in modelling the database. The second part, still in progess, was the development of the CeDRES (Centre de Données aéRoportées & SAFIRE) portal (http://cedres.sedoo.fr) which is responsive and bilingual (French and English) ; and metadata standardization (iso 19115). The main objectives of this project are data preservation and open data access. A first test version of CeDRES portal will be release in mid-February 2016. And operational version is planned for summer 2016. In the future, CeDRES portal will be able to receive and to distribute metadata and data of aircraft currently in service (FALCON-20, ATR-42 and PiperAztec-23). The interoperability implementation and data homogenization are planned in the medium term. The CeDRES portal is part of the French atmospheric chemistry data center AERIS (http://www.aeris-data.fr). Every scientist is invited to browse the catalog and use CEDRES data. Feel free to contact cedres-contact@sedoo.fr for any question.

  3. Framework Development Supporting the Safety Portal

    SciTech Connect

    Prescott, Steven Ralph; Kvarfordt, Kellie Jean; Vang, Leng; Smith, Curtis Lee

    2015-07-01

    In a collaborating scientific research arena it is important to have an environment where analysts have access to a shared repository of information, documents, and software tools, and be able to accurately maintain and track historical changes in models. The new Safety Portal cloud-based environment will be accessible remotely from anywhere regardless of computing platforms given that the platform has available Internet access and proper browser capabilities. Information stored at this environment would be restricted based on user assigned credentials. This report discusses current development of a cloud-based web portal for PRA tools.

  4. Portal Hypertension Secondary to Spontaneous Arterio-Portal Venous Fistulas: Transcatheter Arterial Embolization with n-Butyl Cyanoacrylate and Microcoils

    SciTech Connect

    Yamagami, Takuji; Nakamura, Toshiyuki; Nishimura, Tsunehiko

    2000-09-15

    We report a 73-year-old man with recurrent variceal bleeding due to portal hypertension caused by multiple intrahepatic arterio-portal venous fistulas, which were successfully occluded by embolization with n-butyl cyanoacrylate and micro-coils.

  5. User Needs of Digital Service Web Portals: A Case Study

    ERIC Educational Resources Information Center

    Heo, Misook; Song, Jung-Sook; Seol, Moon-Won

    2013-01-01

    The authors examined the needs of digital information service web portal users. More specifically, the needs of Korean cultural portal users were examined as a case study. The conceptual framework of a web-based portal is that it is a complex, web-based service application with characteristics of information systems and service agents. In…

  6. Considering User Satisfaction in Designing Web-Based Portals.

    ERIC Educational Resources Information Center

    Zazelenchuk, Todd W.; Boling, Elizabeth

    2003-01-01

    Discusses how Web portals can best serve higher education institutions if portal designers first understand and satisfy user needs. Shares findings from a usability study of an Indiana University enterprise portal application, which indicated that many existing interaction design principles still apply. (EV)

  7. Factors Influencing Student Acceptance and Use of Academic Portals

    ERIC Educational Resources Information Center

    Presley, Adrien; Presley, Theresa

    2009-01-01

    Institutions of higher education have increasing turned to web portals as a way to connect with students. These portals are designed to provide students a centralized point of access to information and services. In spite of the efforts put into developing and maintaining these portals, their use by students can be disappointing. The study…

  8. 29 CFR 790.5 - Effect of Portal-to-Portal Act on determination of hours worked.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... or a part of this travel, or if there is a custom or practice to the same effect of the kind... 29 Labor 3 2010-07-01 2010-07-01 false Effect of Portal-to-Portal Act on determination of hours... GENERAL STATEMENT AS TO THE EFFECT OF THE PORTAL-TO-PORTAL ACT OF 1947 ON THE FAIR LABOR STANDARDS ACT...

  9. Multitier Portal Architecture for Thin- and Thick-client Neutron Scattering Experiment Support

    SciTech Connect

    Green, Mark L; Miller, Stephen D

    2007-01-01

    Integration of emerging technologies and design patterns into the three-tier client-server architecture is required in order to provide a scalable and flexible architecture for novice to sophisticated portal user groups. The ability to provide user customizable portal interfaces is rapidly becoming commonplace and is driving the expectations of researchers and scientists in the scientific community. This paper describes an architectural design that maximizes information technology service reuse while providing a customizable user interface that scales with user sophistication and requirements. The Spallation Neutron Source (SNS) located at Oak Ridge National Laboratory provides a state-of-the-art facility ideal for implementation of this infrastructure. The SNS Java-based Science Portal (Tier I) and Open Grid Computing Environment (Tier II) provide thin-client support whereas the GumTree Eclipse Rich Client Platform (Tier III) and Eclipse Integrated Development Environment (Tier IV) provide thickclient support within a multitier portal architecture. Each tier incorporates all of the features of the previous tiers while adding new capabilities based on the user requirements.

  10. GRIP Collaboration Portal: Information Management for a Hurricane Field Campaign

    NASA Astrophysics Data System (ADS)

    Conover, H.; Kulkarni, A.; Garrett, M.; Smith, T.; Goodman, H. M.

    2010-12-01

    NASA’s Genesis and Rapid Intensification Processes (GRIP) experiment, carried out in August and September of 2010, was a complex operation, involving three aircraft and their crews based at different airports, a dozen instrument teams, mission scientists, weather forecasters, project coordinators and a variety of other participants. In addition, GRIP was coordinated with concurrent airborne missions: NOAA’s IFEX and then NSF-funded PREDICT. The GRIP Collaboration Portal was developed to facilitate communication within and between the different teams and serve as an information repository for the field campaign, providing a single access point for project documents, plans, weather forecasts, flight reports and quicklook data. The portal was developed using the Drupal open source content management framework. This presentation will cover both technology and participation issues. Specific examples include: Drupal’s large and diverse open source developer community is an advantage in that we were able to reuse many modules rather than develop capabilities from scratch, but integrating multiple modules developed by many people adds to the overall complexity of the site. Many of the communication capabilities provided by the site, such as discussion forums and blogs, were not used. Participants were diligent about posting necessary documents, but the favored communication method remained email. Drupal's developer-friendly nature allowed for quick development of the customized functionality needed to accommodate the rapidly changing requirements of GRIP experiment. DC-8 Overflight of Hurricane Earl during GRIP Mission

  11. Nitroglycerine effects on portal vein mechanics and oxidative stress in portal hypertension

    PubMed Central

    Vujanac, Andreja; Jakovljevic, Vladimir; Djordjevic, Dusica; Zivkovic, Vladimir; Stojkovic, Mirjana; Celikovic, Dragan; Andjelkovic, Nebojsa; Skevin, Aleksandra Jurisic; Djuric, Dragan

    2012-01-01

    AIM: Тo examine the effects of nitroglycerine on portal vein haemodynamics and oxidative stress in patients with portal hypertension. METHODS: Thirty healthy controls and 39 patients with clinically verified portal hypertension and increased vascular resistance participated in the study. Liver diameters, portal diameters and portal flow velocities were recorded using color flow imaging/pulsed Doppler detection. Cross-section area, portal flow and index of vascular resistance were calculated. In collected blood samples, superoxide anion radical (O2-), hydrogen peroxide (H2O2), index of lipid peroxidation (measured as TBARS) and nitric oxide (NO) as a marker of endothelial response (measured as nitrite-NO2-) were determined. Time-dependent analysis was performed at basal state and in 10th and 15th min after nitroglycerine (sublingual 0.5 mg) administration. RESULTS: Oxidative stress parameters changed significantly during the study. H2O2 decreased at the end of study, probably via O2- mediated disassembling in Haber Weiss and Fenton reaction; O2- increased significantly probably due to increased diameter and tension and decreased shear rate level. Consequently O2- and H2O2 degradation products, like hydroxyl radical, initiated lipid peroxidation. Increased blood flow was to some extent lower in patients than in controls due to double paradoxes, flow velocity decreased, shear rate decreased significantly indicating non Newtonian characteristics of portal blood flow. CONCLUSION: This pilot study could be a starting point for further investigation and possible implementation of some antioxidants in the treatment of portal hypertension. PMID:22294839

  12. Collaboration Portals for NASA's Airborne Field Campaigns

    NASA Technical Reports Server (NTRS)

    Conover, Helen; Kulkami, Ajinkya; Garrett, Michele; Goodman, Michael; Peterson, Walter Arthur; Drewry, Marilyn; Hardin, Danny M.; He, Matt

    2011-01-01

    The University of Alabama in Huntsville (UAH), in collaboration with the Global Hydrology Resource Center, a NASA Earth Science Data Center, has provided information management for a number of NASA Airborne Field campaigns, both hurricane science investigations and satellite instrument validation. Effective field campaign management requires communication and coordination tools, including utilities for personnel to upload and share flight plans, weather forecasts, a variety of mission reports, preliminary science data, and personal photos. Beginning with the Genesis and Rapid Intensification Processes (GRIP) hurricane field campaign in 2010, we have provided these capabilities via a Drupal-based collaboration portal. This portal was reused and modified for the Midlatitude Continental Convective Clouds Experiment (MC3E), part of the Global Precipitation Measurement mission ground validation program. An end goal of these development efforts is the creation of a Drupal profile for field campaign management. This presentation will discuss experiences with Drupal in developing and using these collaboration portals. Topics will include Drupal modules used, advantages and disadvantages of working with Drupal in this context, and how the science teams used the portals in comparison with other communication and collaboration tools.

  13. Collaboration Portals for NASA's Airborne Field Campaigns

    NASA Astrophysics Data System (ADS)

    Conover, H.; Kulkarni, A.; Garrett, M.; Goodman, M.; Petersen, W. A.; Drewry, M.; Hardin, D. M.; He, M.

    2011-12-01

    The University of Alabama in Huntsville (UAH), in collaboration with the Global Hydrology Resource Center, a NASA Earth Science Data Center, has provided information management for a number of NASA Airborne Field campaigns, both hurricane science investigations and satellite instrument validation. Effective field campaign management requires communication and coordination tools, including utilities for personnel to upload and share flight plans, weather forecasts, a variety of mission reports, preliminary science data, and personal photos. Beginning with the Genesis and Rapid Intensification Processes (GRIP) hurricane field campaign in 2010, we have provided these capabilities via a Drupal-based collaboration portal. This portal was reused and modified for the Midlatitude Continental Convective Clouds Experiment (MC3E), part of the Global Precipitation Measurement mission ground validation program. An end goal of these development efforts is the creation of a Drupal profile for field campaign management. This presentation will discuss experiences with Drupal in developing and using these collaboration portals. Topics will include Drupal modules used, advantages and disadvantages of working with Drupal in this context, and how the science teams used the portals in comparison with other communication and collaboration tools.

  14. Regulations.gov Federal Regulatory Portal

    ERIC Educational Resources Information Center

    Ashlin, John; Davis, Richard; Dalecky, Selene; Grasso, Richard; LaPlant, Lisa; Morales, Oscar; Nelson, Jennifer; White, Michael; Whitt, Sharon A.

    2004-01-01

    The Regulations.gov Online Rulemaking Project is 1 of the 24 e-Government Initiatives on the President's Management Agenda (PMA), which was announced by the White House in 2001. The Regulations.gov Web site is the central electronic rulemaking portal for the federal government. Through a single Web site, citizens can search, view, and comment on…

  15. Portal Schools Project, First Year Report.

    ERIC Educational Resources Information Center

    Lutonsky, Linda

    This document discusses the theory and philosophy of the Portal School strategy. According to the author, that strategy is a process for making an environment responsive to change; a way of providing a setting in which site, specific and locally determined programs, and theories can be adapted, implemented, and diffused; and a method for closing…

  16. Intercomprehension: A Portal to Teachers' Intercultural Sensitivity

    ERIC Educational Resources Information Center

    Pinho, Ana Sofia

    2015-01-01

    The development of opportunities for teachers' professional development in plurilingual and intercultural education is a key issue in language teacher education and "intercomprehension" (IC) can provide a potential portal for the development of teachers' intercultural sensitivity. Particularly relevant to this is the creation of powerful…

  17. Opening the Portal to Better Relationships

    ERIC Educational Resources Information Center

    Ipri, Tom; Sell, James H.

    2005-01-01

    Integration of library services into the portal that Lasalle University recently implemented for the entire campus is described. In addition to learning the technical aspects was the need to inspire change in the communication culture of the university and to rethink how the library provides services.

  18. Liver surgery in cirrhosis and portal hypertension

    PubMed Central

    Hackl, Christina; Schlitt, Hans J; Renner, Philipp; Lang, Sven A

    2016-01-01

    The prevalence of hepatic cirrhosis in Europe and the United States, currently 250 patients per 100000 inhabitants, is steadily increasing. Thus, we observe a significant increase in patients with cirrhosis and portal hypertension needing liver resections for primary or metastatic lesions. However, extended liver resections in patients with underlying hepatic cirrhosis and portal hypertension still represent a medical challenge in regard to perioperative morbidity, surgical management and postoperative outcome. The Barcelona Clinic Liver Cancer classification recommends to restrict curative liver resections for hepatocellular carcinoma in cirrhotic patients to early tumor stages in patients with Child A cirrhosis not showing portal hypertension. However, during the last two decades, relevant improvements in preoperative diagnostic, perioperative hepatologic and intensive care management as well as in surgical techniques during hepatic resections have rendered even extended liver resections in higher-degree cirrhotic patients with portal hypertension possible. However, there are few standard indications for hepatic resections in cirrhotic patients and risk stratifications have to be performed in an interdisciplinary setting for each individual patient. We here review the indications, the preoperative risk-stratifications, the morbidity and the mortality of extended resections for primary and metastatic lesions in cirrhotic livers. Furthermore, we provide a review of literature on perioperative management in cirrhotic patients needing extrahepatic abdominal surgery and an overview of surgical options in the treatment of hepatic cirrhosis. PMID:26973411

  19. ExPASy: SIB bioinformatics resource portal

    PubMed Central

    Artimo, Panu; Jonnalagedda, Manohar; Arnold, Konstantin; Baratin, Delphine; Csardi, Gabor; de Castro, Edouard; Duvaud, Séverine; Flegel, Volker; Fortier, Arnaud; Gasteiger, Elisabeth; Grosdidier, Aurélien; Hernandez, Céline; Ioannidis, Vassilios; Kuznetsov, Dmitry; Liechti, Robin; Moretti, Sébastien; Mostaguir, Khaled; Redaschi, Nicole; Rossier, Grégoire; Xenarios, Ioannis; Stockinger, Heinz

    2012-01-01

    ExPASy (http://www.expasy.org) has worldwide reputation as one of the main bioinformatics resources for proteomics. It has now evolved, becoming an extensible and integrative portal accessing many scientific resources, databases and software tools in different areas of life sciences. Scientists can henceforth access seamlessly a wide range of resources in many different domains, such as proteomics, genomics, phylogeny/evolution, systems biology, population genetics, transcriptomics, etc. The individual resources (databases, web-based and downloadable software tools) are hosted in a ‘decentralized’ way by different groups of the SIB Swiss Institute of Bioinformatics and partner institutions. Specifically, a single web portal provides a common entry point to a wide range of resources developed and operated by different SIB groups and external institutions. The portal features a search function across ‘selected’ resources. Additionally, the availability and usage of resources are monitored. The portal is aimed for both expert users and people who are not familiar with a specific domain in life sciences. The new web interface provides, in particular, visual guidance for newcomers to ExPASy. PMID:22661580

  20. Measuring Problem Solving Skills in "Portal 2"

    ERIC Educational Resources Information Center

    Shute, Valerie J.; Wang, Lubin

    2013-01-01

    This paper examines possible improvement to problem solving skills as a function of playing the video game "Portal 2." Stealth assessment is used in the game to evaluate students' problem solving abilities--specifically basic and flexible rule application. The stealth assessment measures will be validated against commonly accepted…

  1. Children as Designers of Web Portals.

    ERIC Educational Resources Information Center

    Large, Andrew; Beheshti, Jamshid; Nesset, Valerie; Bowler, Leanne

    2003-01-01

    Describes the process undertaken by a design team comprising both elementary school students and researchers to design a Web portal intended for use by children. The approach adopted by the team was based upon several design theories related to usability studies: contextual inquiry, participatory design, and cooperative inquiry. Presents…

  2. Impact of Health Portal Enrollment With Email Reminders on Adherence to Clinic Appointments: A Pilot Study

    PubMed Central

    Levy, Janet; L'Engle, Pete; Carlson, Boyd; Ahmad, Asif; Ferranti, Jeffrey

    2011-01-01

    Background Internet portal technologies that provide access to portions of electronic health records have the potential to revolutionize patients’ involvement in their care. However, relatively few descriptions of the demographic characteristics of portal enrollees or of the effects of portal technology on quality outcomes exist. This study examined data from patients who attended one of seven Duke Medicine clinics and who were offered the option of enrolling in and using the Duke Medicine HealthView portal (HVP). The HVP allows patients to manage details of their appointment scheduling and provides automated email appointment reminders in addition to the telephone and mail reminders that all patients receive. Objective Our objective was to test whether portal enrollment with an email reminder functionality is significantly related to decreases in rates of appointment “no-shows,” which are known to impair clinic operational efficiency. Methods Appointment activity during a 1-year period was examined for all patients attending one of seven Duke Medicine clinics. Patients were categorized as portal enrollees or as nonusers either by their status at time of appointment or at the end of the 1-year period. Demographic characteristics and no-show rates among these groups were compared. A binomial logistic regression model was constructed to measure the adjusted impact of HVP enrollment on no-show rates, given confounding factors. To demonstrate the effect of HVP use over time, monthly no-show rates were calculated for patient appointment keeping and contrasted between preportal and postportal deployment periods. Results Across seven clinics, 58,942 patients, 15.7% (9239/58,942) of whom were portal enrollees, scheduled 198,199 appointments with an overall no-show rate of 9.9% (19,668/198,199). We found that HVP enrollees were significantly more likely to be female, white, and privately insured compared with nonusers. Bivariate no-show rate differences between portal

  3. Usefulness of the Medial Portal during Hip Arthroscopy

    PubMed Central

    Kang, Chan; Hwang, Jung-Mo; Park, Eugene J.

    2015-01-01

    The current conventional portals for hip arthroscopic surgery are the anterior, anterolateral, and posterolateral portals. For lesions in the medial anteroinferior or posteroinferior portion of the hip, these portals provide insufficient access to the lesion and consequently lead to incomplete treatment. Thus, in such a situation, a medial portal approach might be helpful. However, operators have avoided this procedure because of the risk of injury to the obturator, femoral neurovascular structures, and the medial femoral circumflex artery. Thus, to overcome the disadvantages of the conventional method for medial lesions of the hip, we performed a cadaveric study to evaluate the technique, usefulness, and risk of the medial portal technique. PMID:26330964

  4. Portal hypertension as portrayed by marked hepatosplenomegaly: case report

    SciTech Connect

    Greene, R.A.

    1987-12-01

    The liver is vulnerable to as host of disease processes, including portal hypertension. This is a severe hepatic condition in which the liver is subject to numerous imbalances: increased hepatic blood flow, increased portal vein pressure due to extrahepatic portal vein obstruction, and/or increases in hepatic blood flow resistance. Although many diseases states may be responsible for the development of portal hypertension, it is most commonly associated with moderately severe or advanced cirrhosis. Advanced, untreated portal hypertension may cause additional complications such as hepatosplenomegaly, gastrointestinal bleeding, and ascites.

  5. Portal vein involvement in hepatocellular carcinoma: dynamic CT features

    SciTech Connect

    Mathieu, D.; Grenier, P.; Larde, D.; Vasile, N.

    1984-07-01

    The authors conducted a retrospective examination of 62 hepatocellular carcinomas, taking dynamic CT scans of selected sections after an intravenous contrast bolus. The proximal portal vein was involved in 40% of cases and distal segment in 16%. Angiographic correlation was available in 23 patients. The characteristic appearance of tumor within the portal vein was noted in many cases; in others, distinction between tumor and bland thrombus could not be made. Peripheral portal vein obstruction was suggested when a small, hypervascular tumor became hypodense during the portal phase of CT. The frequency and significance of these CT signs of portal vein involvement are discussed.

  6. Astronomia.pl: Portal activity in 2006-2007

    NASA Astrophysics Data System (ADS)

    Czart, K.; Pomierny, J.

    2008-06-01

    We present the latest activity of Astronomia.pl - the Polish Astronomy Portal, the most popular internet portal about astronomy in Poland. Astronomia.pl is a wide-ranging portal, covering news, a database of articles, books, lectures, an astronomical calendar, a newsletter, a virtual library of diploma theses, a discussion forum, chat, galleries, a catalogue of websites and other services. The portal also owns several additional services like an on-line lexicon with biographies of astronomers, a website about Polish planetariums and a server for websites created by astronomy amateurs. There is also small part of the portal in English.

  7. Patient Portals: An Underused Resource for Improving Patient Engagement.

    PubMed

    Tulu, Bengisu; Trudel, John; Strong, Diane M; Johnson, Sharon A; Sundaresan, Devi; Garber, Lawrence

    2016-01-01

    The potential of patient portals to improve patient engagement and health outcomes has been discussed for more than a decade. The slow growth in patient portal adoption rates among patients and providers in the United States, despite external incentives, indicates that this is a complex issue. We examined evidence of patient portal use and effects with a focus on the pulmonary domain. We found a paucity of studies of patient portal use in pulmonary practice, and highlight gaps for future research. We also report on the experience of a pulmonary department using a patient portal to highlight the potential of these systems. PMID:26066707

  8. Restriction of drinking water abrogates splanchnic vasodilation and portal hypertension in portal vein-ligated rats.

    PubMed

    Heinemann, Akos; Schuligoi, Rufina; Lippe, Irmgard T; Stauber, Rudolf E

    2009-01-01

    Portal hypertension is associated with splanchnic vasodilation which is claimed responsible for the maintenance of chronically elevated portal pressure. Vasopressin analogues are used in the treatment of acute variceal bleeding, since they effectively reduce splanchnic blood flow and portal pressure. Dehydration stimulates the release of endogenous vasopressin release. Here we compared the effects of deprivation of drinking water for 18 h with those of vasopressin infusion on mesenteric hemodynamics in portal vein-ligated (PVL) and sham-operated (SHAM) rats. Blood flow in the superior mesenteric artery was measured with the ultrasonic transit time shift technique. Deprivation of drinking water had no hemodynamic effects in SHAM rats, but completely reversed the mesenteric hyperemia and portal hypertension in PVL rats to figures measured in SHAM rats, without altering blood pressure. Similarly, intravenous infusion of low doses of arginine vasopressin (1-10 pmol/min) selectively reduced mesenteric blood flow in PVL rats but had little effect in SHAM rats. These data suggest that control of water balance or aquaretic drugs might have beneficial effects on splanchnic hemodynamics and portal pressure in advanced liver disease, possibly by stimulating endogenous vasopressin release. PMID:18987488

  9. Anatomy of the Portal Vein Bifurcation: Implication for Transjugular Intrahepatic Portal Systemic Shunts

    SciTech Connect

    Kwok, Philip Chong-hei Ng, Wai Fu; Lam, Christine Suk-yee; Tsui, Polly Po; Faruqi, Asma

    2003-06-15

    Purpose: The relationship of the portalvein bifurcation to the liver capsule in Asians, which is an important landmark for transjugular intrahepatic portosystemic shunt, has not previously been described. Methods: The anatomy of the portal vein bifurcation was studied in 70 adult Chinese cadavers; it was characterized as intrahepatic or extrahepatic. The length of the exposed portion of the right and left portal veins was measured when the bifurcation was extrahepatic. Results: The portal vein bifurcation was intrahepatic in 37 cadavers (53%) and extrahepatic in 33 cadavers (47%). The mean length of the right and left extrahepatic portal veins was 0.96 cm and 0.85 cm respectively.Both were less than or equal to 2 cm in 94% of the cadavers with extrahepatic bifurcation. There was no correlation between the presence of cirrhosis and the location of the portal vein bifurcation(p 1.0). There was no statistically significant difference in liver mass in cadavers with either extrahepatic or intrahepatic bifurcation (p =0.40). Conclusions: These findings suggest that fortransjugular intrahepatic portosystemic shunt placement, a portal vein puncture 2 cm from the bifurcation will be safe in most cases.

  10. Portal hypertension associated with primary hypoplasia of the hepatic portal vein in dogs.

    PubMed

    Van den Ingh, T S; Rothuizen, J; Meyer, H P

    1995-10-21

    Portal hypertension caused by primary hypoplasia of the portal vein was diagnosed in 42 dogs. The portal hypertension was manifested by the presence of multiple portosystemic collateral vessels. The main clinical signs were retarded growth or weight loss, apathy, intermittent diarrhoea and vomiting, anorexia, abdominal distension and polydipsia. Major findings at physical examination were ascites in 23 dogs and neurological signs in 16 dogs. The dogs had increased activities of liver enzymes in plasma and increased fasting levels of total bile acids and ammonia; in many of the dogs the packed red cell volume, total serum protein and albumin were low. Gross inspection of the portal vein revealed a patent but underdeveloped extrahepatic vein in 13 of the dogs. Microscopic examination of the liver revealed hypoplasia of the intrahepatic portal veins in all the dogs, and this was associated with minor arteriolar proliferation and absence of fibrosis in 12 of them, with moderate to marked arteriolar proliferation often combined with ductular proliferation in 13, and with marked portal fibrosis (formerly described as hepatoportal fibrosis) with a varying number of arteriolar and bile ductular structures in 17 of the dogs. The disease affected mainly young dogs, and was most likely to have been of congenital origin. PMID:8560700

  11. Radioisotopic splenoportography in patients with portal hypertension.

    PubMed

    Samejima, N; Ikeda, K; Yokoyama, Y; Hirata, S

    1989-05-01

    Radio-isotopic splenoportography was performed by injecting 99mTcO4- into the spleens of 46 patients with portal hypertension and 14 patients with various disorders not having portal hypertension. No collateral circulation was demonstrated in the 14 patients without portal hypertension whereas some RI-images of portosystemic collaterals were found in 40 (87.0 per cent) of the 46 patients with portal hypertension. Collaterals were divided into an ascending group and a descending group, the appearance rate of ascending collaterals being 80.4 per cent and that of descending collaterals, 41.3 per cent. There were 3 image patterns in the ascending group, namely, an AZ-pattern in which the azygos vein was demonstrated; a SC-pattern in which the RI-bolus ascended along the esophagus to the neck and the subclavian vein; and an EG-pattern which showed stagnation of the RI-bolus in the esophagogastric region. There were 4 patterns in the descending group, namely; a pattern of gastro-renal caval shunt (GR-pattern); reverse flow patterns into the umbilical or paraumbilical veins (UV-pattern); into the superior mesenteric vein (SMV-pattern); and into the inferior mesenteric vein (IMV-pattern). The appearance of the EG-pattern was seen most frequently (74.4 per cent). The usefulness of this method for surveying the collateral circulation in portal hypertension, estimating the risk of esophageal variceal bleeding and evaluating its treatments, was suggested by the results of this study. PMID:2674500

  12. In vitro vascular responsiveness to norepinephrine in experimental portal hypertension.

    PubMed

    Bomzon, A; Jacob, G; Lee, S S; Meddings, J

    1991-02-01

    It has been postulated that loss of response to norepinephrine accounts in part for the portal hypertension, systemic hypotension, and generalised vascular dilatation of chronic liver disease. The in vitro vascular responsiveness to norepinephrine was measured in aortic rings and portal veins excised from four different rat models of hepatic disease with and without portal hypertension, hepatocellular damage, and hyperbilirubinemia--the carbon tetrachloride (CCl4) cirrhotic rat with portal hypertension, the five-week chronic bile duct ligated and resected (CBDL) cirrhotic rat with portal hypertension and hyperbilirubinemia, the 10-day partial ligated portal vein (PVL) portal hypertensive rat without hepatocellular damage and hyperbilirubinemia, and the three-day bile duct ligated (ABDL) rat with acute hepatocellular damage and hyperbilirubinemia but without portal hypertension. Sham-treated or operated groups for each model were also prepared. Vascular reactivity of the aortic rings to norepinephrine was potentiated in the three portal hypertensive groups, and attenuated in the model of acute cholestasis. No consistent pattern of response to norepinephrine was evident in the portal veins. Based upon the presented in vitro data and the discussed limitations of an in vitro study, we conclude that it is unlikely that the loss of response to norepinephrine accounts for the portal hypertension, systemic hypotension, and generalised vascular dilatation of chronic liver disease. PMID:2040106

  13. Oil-in-water emulsion gels stabilized with chia (Salvia hispanica L.) and cold gelling agents: Technological and infrared spectroscopic characterization.

    PubMed

    Pintado, T; Ruiz-Capillas, C; Jiménez-Colmenero, F; Carmona, P; Herrero, A M

    2015-10-15

    This paper reports on the development of olive oil-in-water emulsion gels containing chia (Salvia hispanica L.) (flour or seed) and cold gelling agents (transglutaminase, alginate or gelatin). The technological and structural characteristics of these emulsion gels were evaluated. Both structural and technological changes in emulsion gels resulting from chilled storage were also determined. The color and texture of emulsion gels depend on both the cold gelling agents used and chilled storage. Lipid oxidation increased (p < 0.05) during storage in emulsion gels containing transglutaminase or alginate. Analyses of the half-bandwidth of the 2923 cm(-1) band and the area of the 3220 cm(-1) band suggest that the order/disorder of the oil lipid chain related to lipid interactions and droplet size in the emulsion gels could be decisive in determining their textural properties. The half-bandwidth of 2923 cm(-1) band and area of 3220 cm(-1) band did not show significant differences during chilled storage. PMID:25952895

  14. Percutaneous Transumbilical Portal Vein Embolization in a Patient with a Ruptured Hepatocellular Carcinoma Supplied by the Portal Vein

    SciTech Connect

    Kim, Soo Chin; Kim, Hyo-Cheol Chung, Jin Wook; Jae, Hwan Jun; Park, Jae Hyung

    2011-02-15

    We describe a case of a ruptured hepatocellular carcinoma supplied by the portal vein that was successfully treated with portal vein embolization via a percutaneous transumbilical approach. A contrast material-enhanced computed tomographic (CT) scan showed the presence of a large hypervascular tumor on portal venous phase as well as right hepatic vein thrombosis and hemoperitoneum that prevented portal vein embolization by the use of the percutaneous and transjugular transhepatic approach. The use of percutaneous transumbilical portal vein embolization can be an alternative option in this situation.

  15. [High resolution laser transient spectroscopic technology under two-stage light gas-gun loading condition and stability study of shocked benzene].

    PubMed

    Zhao, Bei-Jing; Liu, Fu-Sheng; Wang, Wen-Peng; Zhang, Ning-Chao; Feng, Li-Peng; Zhang, Ming-Jian; Xue, Xue-Dong

    2013-10-01

    The present paper reports the high resolution transient Raman laser testing technology under two-stage light gas-gun loading experiment, and its application to studying the Raman spectroscopy of shocked benzene. In the experiments, the frequency shift of C-C stretching vibration (992 cm(-1)) and C-H stretching vibration peak (3 061 cm(-1)) in the low pressure section (less than 8 GPa) varies linearly with the pressure, and the results agree well with reported data in the literature. The structural changes in liquid benzene about 13 GPa were clarified firstly by the Raman spectral technique; the experimental results show that at a pressure of 9.7 GPa, the structural change of liquid benzene has taken place, not reported in the literature about 13 GPa. But the composition in the production is not clear. The measurement system provides an effective means to study the microstructure changes of transparent and translucent material under dynamic loading experiment. PMID:24409699

  16. Using Semantic Web technologies to bridge the Language Gap between Academia and Industry in the Construction Sector

    NASA Astrophysics Data System (ADS)

    Argüello, M.; El-Hasia, A.; Lees, M.

    Semantic Web technologies are emerging technologies which can considerably improve the information sharing process by overcoming the problems of current Web portals. Portals based on Semantic Web technologies represent the next generation of Web portals, however, before industry is willing to adopt Semantic Web technologies it is essential to demonstrate that Semantic Web portals are significantly better than Web portals. This paper focuses on a case study which compares the performance of a traditional Web portal using a keyword-based search engine and a Semantic Web portal using an ontology-based search engine. The empirical results of the comparison performed between these two search engines over an input data set of 100 data provides strong evidence of the tangible benefits of using Semantic Web technologies.

  17. The MG-RAST metagenomics database and portal in 2015.

    PubMed

    Wilke, Andreas; Bischof, Jared; Gerlach, Wolfgang; Glass, Elizabeth; Harrison, Travis; Keegan, Kevin P; Paczian, Tobias; Trimble, William L; Bagchi, Saurabh; Grama, Ananth; Chaterji, Somali; Meyer, Folker

    2016-01-01

    MG-RAST (http://metagenomics.anl.gov) is an open-submission data portal for processing, analyzing, sharing and disseminating metagenomic datasets. The system currently hosts over 200,000 datasets and is continuously updated. The volume of submissions has increased 4-fold over the past 24 months, now averaging 4 terabasepairs per month. In addition to several new features, we report changes to the analysis workflow and the technologies used to scale the pipeline up to the required throughput levels. To show possible uses for the data from MG-RAST, we present several examples integrating data and analyses from MG-RAST into popular third-party analysis tools or sequence alignment tools. PMID:26656948

  18. The MG-RAST Metagenomics Database and Portal in 2015

    DOE PAGESBeta

    Wilke, Andreas; Bischof, Jared; Gerlach, Wolfgang; Glass, Elizabeth; Harrison, Travis; Keegan, Kevin; Paczian, Tobias; Trimble, William L.; Bagchi, Saurabh; Grama, Ananth; et al

    2015-12-09

    MG-RAST (http://metagenomics.anl.gov) is an opensubmission data portal for processing, analyzing, sharing and disseminating metagenomic datasets. Currently, the system hosts over 200 000 datasets and is continuously updated. The volume of submissions has increased 4-fold over the past 24 months, now averaging 4 terabasepairs per month. In addition to several new features, we report changes to the analysis workflow and the technologies used to scale the pipeline up to the required throughput levels. Lastly, to show possible uses for the data from MG-RAST, we present several examples integrating data and analyses from MG-RAST into popular third-party analysis tools or sequence alignmentmore » tools.« less

  19. The MG-RAST Metagenomics Database and Portal in 2015

    SciTech Connect

    Wilke, Andreas; Bischof, Jared; Gerlach, Wolfgang; Glass, Elizabeth; Harrison, Travis; Keegan, Kevin; Paczian, Tobias; Trimble, William L.; Bagchi, Saurabh; Grama, Ananth; Chaterji, Somali; Meyer, Folker

    2015-12-09

    MG-RAST (http://metagenomics.anl.gov) is an opensubmission data portal for processing, analyzing, sharing and disseminating metagenomic datasets. Currently, the system hosts over 200 000 datasets and is continuously updated. The volume of submissions has increased 4-fold over the past 24 months, now averaging 4 terabasepairs per month. In addition to several new features, we report changes to the analysis workflow and the technologies used to scale the pipeline up to the required throughput levels. Lastly, to show possible uses for the data from MG-RAST, we present several examples integrating data and analyses from MG-RAST into popular third-party analysis tools or sequence alignment tools.

  20. The MG-RAST metagenomics database and portal in 2015

    PubMed Central

    Wilke, Andreas; Bischof, Jared; Gerlach, Wolfgang; Glass, Elizabeth; Harrison, Travis; Keegan, Kevin P.; Paczian, Tobias; Trimble, William L.; Bagchi, Saurabh; Grama, Ananth; Chaterji, Somali; Meyer, Folker

    2016-01-01

    MG-RAST (http://metagenomics.anl.gov) is an open-submission data portal for processing, analyzing, sharing and disseminating metagenomic datasets. The system currently hosts over 200 000 datasets and is continuously updated. The volume of submissions has increased 4-fold over the past 24 months, now averaging 4 terabasepairs per month. In addition to several new features, we report changes to the analysis workflow and the technologies used to scale the pipeline up to the required throughput levels. To show possible uses for the data from MG-RAST, we present several examples integrating data and analyses from MG-RAST into popular third-party analysis tools or sequence alignment tools. PMID:26656948

  1. The GOBLET training portal: a global repository of bioinformatics training materials, courses and trainers

    PubMed Central

    Corpas, Manuel; Jimenez, Rafael C.; Bongcam-Rudloff, Erik; Budd, Aidan; Brazas, Michelle D.; Fernandes, Pedro L.; Gaeta, Bruno; van Gelder, Celia; Korpelainen, Eija; Lewitter, Fran; McGrath, Annette; MacLean, Daniel; Palagi, Patricia M.; Rother, Kristian; Taylor, Jan; Via, Allegra; Watson, Mick; Schneider, Maria Victoria; Attwood, Teresa K.

    2015-01-01

    Summary: Rapid technological advances have led to an explosion of biomedical data in recent years. The pace of change has inspired new collaborative approaches for sharing materials and resources to help train life scientists both in the use of cutting-edge bioinformatics tools and databases and in how to analyse and interpret large datasets. A prototype platform for sharing such training resources was recently created by the Bioinformatics Training Network (BTN). Building on this work, we have created a centralized portal for sharing training materials and courses, including a catalogue of trainers and course organizers, and an announcement service for training events. For course organizers, the portal provides opportunities to promote their training events; for trainers, the portal offers an environment for sharing materials, for gaining visibility for their work and promoting their skills; for trainees, it offers a convenient one-stop shop for finding suitable training resources and identifying relevant training events and activities locally and worldwide. Availability and implementation: http://mygoblet.org/training-portal Contact: manuel.corpas@tgac.ac.uk PMID:25189782

  2. A Data-Centered Collaboration Portal to Support Global Carbon-Flux Analysis

    SciTech Connect

    Agarwal, Deborah A.; Humphrey, Marty; Beekwilder, Norm; Jackson, Keith; Goode, Monte; van Ingen, Catharine

    2009-04-07

    Carbon-climate, like other environmental sciences, has been changing. Large-scalesynthesis studies are becoming more common. These synthesis studies are often conducted by science teams that are geographically distributed and on datasets that are global in scale. A broad array of collaboration and data analytics tools are now available that could support these science teams. However, building tools that scientists actually use is hard. Also, moving scientists from an informal collaboration structure to one mediated by technology often exposes inconsistencies in the understanding of the rules of engagement between collaborators. We have developed a scientific collaboration portal, called fluxdata.org, which serves the community of scientists providing and analyzing the global FLUXNET carbon-flux synthesis dataset. Key things we learned or re-learned during our portal development include: minimize the barrier to entry, provide features on a just-in-time basis, development of requirements is an on-going process, provide incentives to change leaders and leverage the opportunity they represent, automate as much as possible, and you can only learn how to make it better if people depend on it enough to give you feedback. In addition, we also learned that splitting the portal roles between scientists and computer scientists improved user adoption and trust. The fluxdata.org portal has now been in operation for ~;;1.5 years and has become central to the FLUXNET synthesis efforts.

  3. Understanding Patient Portal Use: Implications for Medication Management

    PubMed Central

    Mayberry, Lindsay Satterwhite; Wallston, Kenneth A; Johnson, Kevin B; Elasy, Tom A

    2013-01-01

    Background The Internet can be leveraged to provide disease management support, including medication adherence promotion that, when tailored, can effectively improve adherence to medications. The growing adoption of patient portals represents an opportunity to support medication management and adherence more broadly, but virtually no data exist about the real and potential impact of existing portals on these outcomes. Objective We sought to (1) understand who uses an existing patient portal and reasons for use and nonuse, (2) understand how portal users are using a portal to manage their medications, and (3) explore participants’ ideas for improving portal functionality for medication management and adherence support. Methods A total of 75 adults with type 2 diabetes participated in a mixed-methods study involving focus groups, a survey, and a medical chart review. We used quantitative data to identify differences between portal users and nonusers, and to test the relationship between the frequency of portal use and glycemic control among users. We used qualitative methods to understand how and why participants use a portal and their ideas for improving its medication management functionality. Results Of the enrolled participants, 81% (61/75) attended a focus group and/or completed a survey; portal users were more likely than nonusers to participate in that capacity (Fisher exact test; P=.01). Users were also more likely than nonusers to be Caucasian/white (Fisher exact test; P<.001), have higher incomes (Fisher exact test; P=.005), and be privately insured (Fisher exact test; P<.001). Users also tended to have more education than nonusers (Mann–Whitney U; P=.05), although this relationship was not significant at P<.05. Among users, more frequent use of a portal was associated with better A1C (Spearman rho =–0.30; P=.02). Reasons for nonuse included not knowing about the portal (n=3), not having access to a computer (n=3), or having a family member serve as

  4. Spectroscopic infrared ellipsometry

    NASA Astrophysics Data System (ADS)

    Roseler, A.

    1992-03-01

    The spectroscopic infrared ellipsometry (SIRE) by means of the combination of a photometric ellipsometer with a Fourier transform spectrometer is used to measure optical properties in the infrared. From the observed four Stokes parameters, the spectrum of the degree of polarization after the reflection at the sample is calculated and discussed.

  5. Spectroscopic wear detector

    NASA Technical Reports Server (NTRS)

    Madzsar, George C. (Inventor)

    1993-01-01

    The elemental composition of a material exposed to hot gases and subjected to wear is determined. Atoms of an elemental species not appearing in this material are implanted in a surface at a depth based on the maximum allowable wear. The exhaust gases are spectroscopically monitored to determine the exposure of these atoms when the maximum allowable wear is reached.

  6. Application of Spectroscopic Analysis Techniques to the Determination of Slag Structures and Properties: Effect of Water Vapor on Slag Chemistry Relevant to a Novel Flash Ironmaking Technology

    NASA Astrophysics Data System (ADS)

    Mohassab-Ahmed, M. Y.; Sohn, H. Y.

    2013-11-01

    Flash ironmaking technology is an ecofriendly process for producing iron from iron oxide concentrates via a flash reactor that uses gaseous fuels and reductants that reduce energy consumption and minimize greenhouse gas emissions. It has the potential to achieve steelmaking in a single, continuous process. The phase equilibria and chemistry of selected slag systems were investigated during the development of a novel flash ironmaking process. Among the proposed reductants and fuels are H2, natural gas, and coal gas. In different ironmaking processes, the molten bath (iron-slag bath) is expected to be at equilibrium with gas atmospheres of H2/H2O, CO/CO2/H2/H2O, and CO/CO2. The first two gas mixtures were used to represent the processes based on H2 or natural gas/coal gas, respectively, whereas the CO/CO2 mixture was used for a comparison. The slag composition of interest in this process was selected to resemble that of the blast furnace and is based on the CaO-MgO-SiO2-Al2O3-FeO-MnO-P2O5 system with CaO/SiO2 in the range 0.8-1.4. The temperature range was 1550-1650°C encompassing a wide range of expected ironmaking temperatures for the novel flash process. The oxygen partial pressure was maintained in the reducing range of 10-10-10-9 atm in the three gas atmospheres. It was found that H2O dramatically affects the chemistry of the slag and strongly affects the phase equilibria in the slag as well as the equilibrium distribution of elements between slag and molten metal. The effects of water vapor on the chemistry of the slag as well as the equilibrium reactions involving the slag have been studied for the first time.

  7. Sunshot Initiative High Penetration Solar Portal

    DOE Data Explorer

    The DOE SunShot Initiative is a collaborative national initiative to make solar energy cost-competitive with other forms of energy by the end of the decade. Reducing the installed cost of solar energy systems by about 75% will drive widespread large-scale adoption of this renewable energy and restore U.S. leadership in the global clean energy race. The High Penetration Solar Portal was created as a resource to aggregate the most relevant and timely information related to high penetration solar scenarios and integrating solar into the grid. The site is designed so that utilities, grant awardees, regulators, researchers, and other solar professionals can easily share data, case studies, lessons learned, and demonstration project findings. [from https://solarhighpen.energy.gov/about_the_high_penetration_solar_portal

  8. Photonic dark matter portal and quantum physics

    NASA Astrophysics Data System (ADS)

    Alavi, S. A.; Kazemian, F. S.

    2016-02-01

    We study a model of dark matter in which the hidden sector interacts with standard model particles via a hidden photonic portal. We investigate the effects of this new interaction on the hydrogen atom, including the Stark, Zeeman and hyperfine effects. Using the accuracy of the measurement of energy, we obtain an upper bound for the coupling constant of the model as f ⩽ 10-12. We also calculate the contribution from the hidden photonic portal to the anomalous magnetic moment of the muon as aμ ⩽ 2.2 × 10-23 (for the dark particle mass scale 100 MeV), which provides an important probe of physics beyond the standard model.

  9. Phase contrast portal imaging using synchrotron radiation

    NASA Astrophysics Data System (ADS)

    Umetani, K.; Kondoh, T.

    2014-07-01

    Microbeam radiation therapy is an experimental form of radiation treatment with great potential to improve the treatment of many types of cancer. We applied a synchrotron radiation phase contrast technique to portal imaging to improve targeting accuracy for microbeam radiation therapy in experiments using small animals. An X-ray imaging detector was installed 6.0 m downstream from an object to produce a high-contrast edge enhancement effect in propagation-based phase contrast imaging. Images of a mouse head sample were obtained using therapeutic white synchrotron radiation with a mean beam energy of 130 keV. Compared to conventional portal images, remarkably clear images of bones surrounding the cerebrum were acquired in an air environment for positioning brain lesions with respect to the skull structure without confusion with overlapping surface structures.

  10. Phase contrast portal imaging using synchrotron radiation

    SciTech Connect

    Umetani, K.; Kondoh, T.

    2014-07-15

    Microbeam radiation therapy is an experimental form of radiation treatment with great potential to improve the treatment of many types of cancer. We applied a synchrotron radiation phase contrast technique to portal imaging to improve targeting accuracy for microbeam radiation therapy in experiments using small animals. An X-ray imaging detector was installed 6.0 m downstream from an object to produce a high-contrast edge enhancement effect in propagation-based phase contrast imaging. Images of a mouse head sample were obtained using therapeutic white synchrotron radiation with a mean beam energy of 130 keV. Compared to conventional portal images, remarkably clear images of bones surrounding the cerebrum were acquired in an air environment for positioning brain lesions with respect to the skull structure without confusion with overlapping surface structures.

  11. [Pathophysiology of portal hypertension, what's new?].

    PubMed

    Kim, Moon Young; Baik, Soon Koo

    2010-09-01

    Portal hypertension (PHT) is associated with changes in the intrahepatic, systemic and portosystemic collateral circulations. Alteration in vasoreactivity (vasodilation and vasoconstriction) plays a central role in the pathogenesis of PHT by contributing to increased intrahepatic resistance, hyperdynamic circulation and the expansion of the collateral circulation. PHT is also importantly characterized by changes in vascular structure; termed vascular remodeling, which is an adaptive response of the vessel wall that occurs in response to chronic changes in the environment such as shear stress. Angiogenesis, the sprouting of new blood vessels, also occurs in PHT, especially in the expansion of the portosystemic collateral circulation. These complementary processes of vasoreactivity, vascular remodeling and angiogenesis represent important targets in the research for the treatment of portal hypertension. PMID:20847603

  12. The QUEST Data Portal Visualisation Service

    NASA Astrophysics Data System (ADS)

    Norton, Peter; Pascoe, Stephen; Juckes, Martin

    2010-05-01

    The QUEST (Quantifying and Understanding the Earth System) Data Portal Visualisation Service provides access to a wide range of earth system science datasets, such as: observational climate composites, climate model projections and simulations, a biodiversity index and human population. The user interface allows the user to navigate and view the datasets through Open Geospatial Consortium compliant Web Map Servers. Presenting a wide range of datasets through a generic interface (which needs to work within a range of browsers, their versions and configurations) creates many conflicting demands. This poster describes the strategies adopted to create a portal which gives flexible access to a wide range of datasets, and maintains clear links back to detailed descriptions of the data.

  13. Portal Vein Embolization: What Do We Know?

    SciTech Connect

    Denys, Alban; Prior, John; Bize, Pierre; Duran, Rafael; Baere, Thierry De; Halkic, Nermin; Demartines, Nicolas

    2012-10-15

    Portal vein embolization (PVE) has been developed to increase the size of the future remnant liver (FRL) left in place after major hepatectomy, thus reducing the risk of postoperative liver insufficiency. PVE consist in embolizing preoperatively portal branches of the segments that will be resected. Indication is based on preoperative measurements of the FRL by computed tomography and its ratio with either the theoretical liver volume or by direct measurement of the functional liver volume. After PVE, the volume and function of the FRL increases in 3 to 6 weeks, permitting extensive resections in patients otherwise contraindicated for liver resection. The PVE technique is variable from one center to another; however n-butyl-cyano-acrylate provides an interesting compromise between hypertrophy rate and procedure risk.

  14. Treatment of ectopic varices with portal hypertension.

    PubMed

    Sato, Takahiro

    2015-06-28

    Ectopic varices are unusual with portal hypertension and can involve any site along the digestive tract outside the gastroesophageal region. Hemorrhage from ectopic varices generally are massive and life threatening. Diagnosis of ectopic varices is difficult and subsequent treatment is also difficult; the optimal treatment has not been established. Recently, interventional radiology and endoscopic treatments have been carried out successfully for hemorrhage from ectopic varices. PMID:26140080

  15. On flattening filter-free portal dosimetry.

    PubMed

    Pardo, Eduardo; Castro Novais, Juan; Molina López, María Yolanda; Ruiz Maqueda, Sheila

    2016-01-01

    Varian introduced (in 2010) the option of removing the flattening filter (FF) in their C-Arm linacs for intensity-modulated treatments. This mode, called flattening filter-free (FFF), offers the advantage of a greater dose rate. Varian's "Portal Dosimetry" is an electronic portal imager device (EPID)-based tool for IMRT verification. This tool lacks the capability of verifying flattening filter-free (FFF) modes due to saturation and lack of an image prediction algorithm. (Note: the latest versions of this software and EPID correct these issues.) The objective of the present study is to research the feasibility of said verifications (with the older versions of the software and EPID). By placing the EPID at a greater distance, the images can be acquired without saturation, yielding a linearity similar to the flattened mode. For the image prediction, a method was optimized based on the clinically used algorithm (analytical anisotropic algorithm (AAA)) over a homogeneous phantom. The depth inside the phantom and its electronic density were tailored. An application was developed to allow the conversion of a dose plane (in DICOM format) to Varian's custom format for Portal Dosimetry. The proposed method was used for the verification of test and clinical fields for the three qualities used in our institution for IMRT: 6X, 6FFF and 10FFF. The method developed yielded a positive verification (more than 95% of the points pass a 2%/2 mm gamma) for both the clinical and test fields. This method was also capable of "predicting" static and wedged fields. A workflow for the verification of FFF fields was developed. This method relies on the clinical algorithm used for dose calculation and is able to verify the FFF modes, as well as being useful for machine quality assurance. The procedure described does not require new hardware. This method could be used as a verification of Varian's Portal Dose Image Prediction. PMID:27455487

  16. Diavideos: a diabetes health video portal.

    PubMed

    Sánchez-Bocanegra, C L; Rivero-Rodriguez, A; Fernández-Luque, L; Sevillano, J L

    2013-01-01

    Diavideos is a web platform that collects trustworthy diabetes health videos from YouTube and offers them in a easy way. YouTube is a big repository of health videos, but good content is sometimes mixed with misleading and harmful videos such as promoting anorexia [1]. Diavideos is a web portal that provides easy access to a repository of trustworthy diabetes videos. This poster describes Diavideos and explains the crawling method used to retrieve these videos from trusted channels. PMID:23920715

  17. Capsule Endoscopy for Portal Hypertensive Enteropathy

    PubMed Central

    2016-01-01

    Portal hypertensive enteropathy (PHE) is a mucosal abnormality of the small bowel that is observed in patients with portal hypertension (PH) and can lead to gastrointestinal bleeding and anemia. The pathogenesis is still not completely understood. The introduction of new endoscopic methods, including capsule endoscopy (CE) or balloon-assisted enteroscopy, has increased the detection of these abnormalities. CE can also serve as a road map for deciding subsequent interventions and evaluating the treatment effect. The prevalence of PHE is reportedly 40–70% in patients with PH. Endoscopic findings can be roughly divided into vascular and nonvascular lesions such as inflammatory-like lesions. Traditionally, PHE-associated factors include large esophageal varices, portal hypertensive gastropathy or colopathy, Child-Turcotte-Pugh class B or C, a history of variceal treatment, and acute gastrointestinal bleeding. More recently, on using scoring systems, a high computed tomography or transient elastography score was reportedly PHE-related factors. However, the prevalence of PHE and its related associated factors remain controversial. The management of PHE has not yet been standardized. It should be individualized according to each patient's situation, the availability of therapy, and each institutional expertise. PMID:26819613

  18. Interventional Radiologic Treatment for Idiopathic Portal Hypertension

    SciTech Connect

    Hirota, Shozo; Ichikawa, Satoshi; Matsumoto, Shinichi; Motohara, Tomofumi; Fukuda, Tetsuya; Yoshikawa, Takeshi

    1999-07-15

    Purpose: To evaluate the usefulness of interventional radiological treatment for idiopathic portal hypertension. Methods: Between 1995 and 1998, we performed an interventional radiological treatment in five patients with idiopathic portal hypertension, four of whom had refused surgery and one of whom had undergone surgery. Three patients with gastroesophageal varices (GEV) were treated by partial splenic embolization (PSE), one patient with esophageal varices (EV) and massive ascites by transjugular intrahepatic portosytemic shunt (TIPS) and PSE, and one patient with GEV by percutaneous transhepatic obliteration (PTO). Midterm results were analyzed in terms of the effect on esophageal and/or gastric varices. Results: In one woman with severe GEV who underwent three sessions of PSE, there was endoscopic confirmation that the GEV had disappeared. In one man his EV shrunk markedly after two sessions of PSE. In two patients slight reduction of the EV was obtained with one application of PSE combined with endoscopic variceal ligation therapy. PTO for GV in one patient resulted in good control of the varices. All patients have survived for 16-42 months since the first interventional treatment, and varices are well controlled. Conclusion: Interventional radiological treatment is effective for patients with idiopathic portal hypertension, whether or not they have undergone surgery.

  19. Capsule Endoscopy for Portal Hypertensive Enteropathy.

    PubMed

    Jeon, Seong Ran; Kim, Jin-Oh

    2016-01-01

    Portal hypertensive enteropathy (PHE) is a mucosal abnormality of the small bowel that is observed in patients with portal hypertension (PH) and can lead to gastrointestinal bleeding and anemia. The pathogenesis is still not completely understood. The introduction of new endoscopic methods, including capsule endoscopy (CE) or balloon-assisted enteroscopy, has increased the detection of these abnormalities. CE can also serve as a road map for deciding subsequent interventions and evaluating the treatment effect. The prevalence of PHE is reportedly 40-70% in patients with PH. Endoscopic findings can be roughly divided into vascular and nonvascular lesions such as inflammatory-like lesions. Traditionally, PHE-associated factors include large esophageal varices, portal hypertensive gastropathy or colopathy, Child-Turcotte-Pugh class B or C, a history of variceal treatment, and acute gastrointestinal bleeding. More recently, on using scoring systems, a high computed tomography or transient elastography score was reportedly PHE-related factors. However, the prevalence of PHE and its related associated factors remain controversial. The management of PHE has not yet been standardized. It should be individualized according to each patient's situation, the availability of therapy, and each institutional expertise. PMID:26819613

  20. ENCODE data at the ENCODE portal.

    PubMed

    Sloan, Cricket A; Chan, Esther T; Davidson, Jean M; Malladi, Venkat S; Strattan, J Seth; Hitz, Benjamin C; Gabdank, Idan; Narayanan, Aditi K; Ho, Marcus; Lee, Brian T; Rowe, Laurence D; Dreszer, Timothy R; Roe, Greg; Podduturi, Nikhil R; Tanaka, Forrest; Hong, Eurie L; Cherry, J Michael

    2016-01-01

    The Encyclopedia of DNA Elements (ENCODE) Project is in its third phase of creating a comprehensive catalog of functional elements in the human genome. This phase of the project includes an expansion of assays that measure diverse RNA populations, identify proteins that interact with RNA and DNA, probe regions of DNA hypersensitivity, and measure levels of DNA methylation in a wide range of cell and tissue types to identify putative regulatory elements. To date, results for almost 5000 experiments have been released for use by the scientific community. These data are available for searching, visualization and download at the new ENCODE Portal (www.encodeproject.org). The revamped ENCODE Portal provides new ways to browse and search the ENCODE data based on the metadata that describe the assays as well as summaries of the assays that focus on data provenance. In addition, it is a flexible platform that allows integration of genomic data from multiple projects. The portal experience was designed to improve access to ENCODE data by relying on metadata that allow reusability and reproducibility of the experiments. PMID:26527727

  1. ENCODE data at the ENCODE portal

    PubMed Central

    Sloan, Cricket A.; Chan, Esther T.; Davidson, Jean M.; Malladi, Venkat S.; Strattan, J. Seth; Hitz, Benjamin C.; Gabdank, Idan; Narayanan, Aditi K.; Ho, Marcus; Lee, Brian T.; Rowe, Laurence D.; Dreszer, Timothy R.; Roe, Greg; Podduturi, Nikhil R.; Tanaka, Forrest; Hong, Eurie L.; Cherry, J. Michael

    2016-01-01

    The Encyclopedia of DNA Elements (ENCODE) Project is in its third phase of creating a comprehensive catalog of functional elements in the human genome. This phase of the project includes an expansion of assays that measure diverse RNA populations, identify proteins that interact with RNA and DNA, probe regions of DNA hypersensitivity, and measure levels of DNA methylation in a wide range of cell and tissue types to identify putative regulatory elements. To date, results for almost 5000 experiments have been released for use by the scientific community. These data are available for searching, visualization and download at the new ENCODE Portal (www.encodeproject.org). The revamped ENCODE Portal provides new ways to browse and search the ENCODE data based on the metadata that describe the assays as well as summaries of the assays that focus on data provenance. In addition, it is a flexible platform that allows integration of genomic data from multiple projects. The portal experience was designed to improve access to ENCODE data by relying on metadata that allow reusability and reproducibility of the experiments. PMID:26527727

  2. Campus Portals: Supportive Mechanisms for University Communication, Collaboration, and Organizational Change.

    ERIC Educational Resources Information Center

    Eisler, David L.

    2001-01-01

    University portals provide a new computerized interface between colleges and constituent groups. This article discusses: campus portals and possible features they may contain, nine strategies for portal projects, collaborative mechanisms to develop and implement portal projects, criteria for determination of campus portal readiness, potential…

  3. Explosives detection portal for high-volume personnel screening

    NASA Astrophysics Data System (ADS)

    Parmeter, John E.; Linker, Kevin L.; Rhykerd, Charles L.; Hannum, David W.; Bouchier, Francis A.

    1998-12-01

    We discuss a trace explosive detection portal for high-volume personnel screening, which has been developed recently at Sandia National Laboratories (SNL), using funding provided by the Federal Aviation Administration (FAA) and the Department of Energy (DOE) Office of Safeguards and Security (OSS). This portal screens individuals for explosives using noninvasive means to collect explosive residue in the forms of vapor and particulate contamination. The portal combines a commercially available ion mobility spectrometer (IMS) with a preconcentrator developed at SNL to perform detection of explosives. The prototype portal has undergone one series of tests at the Albuquerque International Airport, and we are now proceeding to develop an improved, second-generation portal, and to find a company to market the portal.

  4. The portal immunosuppressive storm: relevance to islet transplantation?

    PubMed

    Shapiro, A M James; Gallant, Heather L; Hao, Er Geng; Lakey, Jonathan R T; McCready, Tara; Rajotte, Ray V; Yatscoff, Randall W; Kneteman, Norman M

    2005-02-01

    Outcomes in clinical islet transplantation improved substantially with the introduction of combined sirolimus and tacrolimus immunosuppression. However, multiple islet preparations are often required to achieve insulin independence, suggesting that islet engraftment may not be optimal when these agents are absorbed via the portal vein. The current study was designed to assess the differential concentrations of immunosuppressive drugs within the portal and systemic circulations of a large animal model, to assess the local concentrations of drugs to which islets are exposed early after implantation. Chronic catheters were placed in the portal vein and carotid artery of 6 mongrel dogs, and immunosuppressants were administered orally. Blood samples were drawn simultaneously from portal and systemic catheters, and drug concentrations were analyzed. Peak immunosuppressant levels as well as area under the curve were dramatically elevated in portal blood relative to systemic levels for all drugs tested. This "portal storm" of immunosuppression may be relevant to intrahepatic islet transplantation. PMID:15665744

  5. Development of a trace explosives detection portal for personnel screening

    SciTech Connect

    Parmeter, J.E.; Linker, K.L.; Rhykerd, C.L. Jr.; Bouchier, F.A.; Hannum, D.W.

    1998-08-01

    The authors discuss the development, design, and operation of a walk-through trace detection portal designed to screen personnel for explosives. Developed at Sandia National Laboratories (SNL) with primary funding from the Federal Aviation Administration (FAA) and additional support from the Department of Energy office of Safeguards and Security, this portal is intended primarily for use in airport terminals and in other localities where a very high throughput of pedestrian traffic is combined with stringent security requirements. The portal is capable of detecting both vapor and particulate contamination, with the collection of explosive material being based upon the entrainment of that material in air flows over the body of the person being screened. This portal is capable of detecting most types of common high explosives of interest to the FAA. The authors discuss the results of field testing of the portal in the Albuquerque International Airport in September, 1997 and more recent steps towards commercialization of the portal.

  6. Disastrous Portal Vein Embolization Turned into a Successful Intervention

    SciTech Connect

    Dobrocky, Tomas; Kettenbach, Joachim; Lopez-Benitez, Ruben Kara, Levent

    2015-10-15

    Portal vein embolization (PVE) may be performed before hemihepatectomy to increase the volume of future liver remnant (FLR) and to reduce the risk of postoperative liver insufficiency. We report the case of a 71-year-old patient with hilar cholangiocarcinoma undergoing PVE with access from the right portal vein using a mixture of n-butyl-2-cyanoacrylate and ethiodized oil. During the procedure, nontarget embolization of the left portal vein occurred. An aspiration maneuver of the polymerized plug failed; however, the embolus obstructing portal venous flow in the FLR was successfully relocated into the right portal vein while carefully bypassing the plug with a balloon catheter, inflating the balloon, and pulling the plug into the main right portal vein.

  7. EMODnet Physical Parameters (EMODNet PP) Portal

    NASA Astrophysics Data System (ADS)

    Novellino, A.; Schaap, D.; Manzella, G. M. R.; Pouliquen, S.; Gorringe, P.

    2012-04-01

    In December 2007 the European Parliament and Council adopted a common text for the Marine Strategy Framework Directive which aims to achieve environmentally healthy marine waters by 2020. This Directive includes an initiative for an overarching European Marine Observation and Data Network (EMODNet). During the one-year consultation phase that followed the release of the EU Green Paper on a Future Maritime Policy for the European Union, stakeholders gave an overwhelming positive response. Facilitating access to high quality marine data will resolve difficulties and stimulate an expansion of value-added public and commercial services, lay the foundations for sound governance and reduce uncertainties on human impact on the planet as well as of forecasts relating to the future state of the marine environment. Better and linked marine data will have an immediate impact on the planning of environmental policy and mitigation measures, and will also facilitate impact assessments and scientific work. The overall objectives of the EMODnet Physical Parameters (EMODNet PP) preparatory action is to provide access to archived and near real-time data on physical conditions in Europe's seas and oceans by means of a dedicated Pilot Portal and to determine how well the data meet the needs of users from industry, public authorities and scientists. The latter implicates that it is also an objective to identify data gaps and arguments why these gaps should be filled in future monitoring. This project will contribute towards the definition of an operational European Marine Observation and Data Network (EMODnet). This is done done by: 1. providing through a portal: a. access to marine data from measurement stations and ferryboxes. Both near real-time and archived data of time series are to be made available. b. metadata for these data sets using EMODnet/INSPIRE standards. c. metadata maps and overviews for whole sea-basins showing the availability of data and monitoring intensity of that

  8. A Climate Information Portal for Copernicus: a central portal for European climate services?

    NASA Astrophysics Data System (ADS)

    Juckes, Martin; Swart, Rob; Thysse, Peter; Som de Cerff, Wim; Groot, Annemarie; Bennett, Victoria; Costa, Luis; Lückenkötter, Johannes; Callaghan, Sarah

    2015-04-01

    The FP7 project "Climate Information Portal for Copernicus" (CLIPC) is developing a demonstration portal for the Copernicus Climate Change Service (C3S). This project is one of a suite of FP7 research activities which are administratively independent of Copernicus, focussed on creating the technical and scientific building blocks needed for the service. It is to be expected that at EGU 2015 there will be many presentations describing portals delivering new and innovative ranges of services. It would be unwise to seek to replace all this creative activity with a single portal -- instead CLIPC is designing a portal to make distributed resources more accessible through flexible discovery systems. CLIPC needs to deliver more than a directory of resources: resources need to be presented in common protocols so that users can access multiple datasets. More information about the project objectives is available at www.clipc.eu. The gulf between the climate science communities and the end user communities is a central challenge being addressed in the project. It is important to understand that there is significant diversity and multiple communication barriers within these two sets of communities as well as between them. The CLIPC services must presentation will provide a review of progress towards this ambitious goal, through a discussion of user requirements activities, an overview of the proposed architecture, work on assessing and adjusting model biasses, and a discussion of the climate impact indicators which will be provided through the portal. When looking at the usability of data for the various users, CLIPC will implement a set of services functioning as a "knowledge base" supplying information to users about the data, including definitions of terminology used, quality of datasets, versioning, and user annotations.

  9. High-end spectroscopic diffraction gratings: design and manufacturing

    NASA Astrophysics Data System (ADS)

    Glaser, Tilman

    2015-02-01

    Diffraction gratings are key components for spectroscopic systems. For high-end applications, they have to meet advanced requirements as, e.g., maximum efficiency, lowest possible scattered light level, high numerical aperture, and minimal aberrations. Diffraction gratings are demanded to allow spectrometer designs with highest resolution, a maximal étendue, and minimal stray light, built within a minimal volume. This tutorial is intended to provide an overview of different high-end spectroscopic gratings, their theoretical design and manufacturing technologies.

  10. [Surgical treatment of portal hypertension: the state of art].

    PubMed

    Shertsinger, A G; Zhigalova, S B; Lebezev, V M; Manukian, G V; Kitsenko, E A

    2013-01-01

    The article highlights modern approaches to the treatment of portal hypertension. The differential tactics is based on the type of portal hypertension, functional liver state, urgency of the situation and severity of blood loss, localization and stage of varices, concomitant diseases, etc. The role of miniinvasive methods is stressed. The reasonability of general treatment algorithm of portal hypertention in specialized centers is proved. PMID:23503380

  11. Who are Portal Users vs. Early E-Visit Adopters? A Preliminary Analysis

    PubMed Central

    Jung, C.; Padman, R.; Shevchik, G.; Paone, S.

    2011-01-01

    Patient portals and eVisits are gaining momentum due to increasing consumer demand for improved access to clinical information and services, availability of new technologies to deploy them and development of reimbursement initiatives by major payers. Despite increasing interest in online health consultation by consumers, adoption has been slow and little is known about the users of such services. In this study, we analyze the key features that distinguish early adopters of eVisits from portal consumers, in aggregate and in four distinct ambulatory practices, using data from a major healthcare provider in Western Pennsylvania. Preliminary results indicate that out of 10,532 portal users, the 336 patients who submitted 446 eVisits between April 1, 2009 and May 31, 2010 are younger on average, predominantly female, not retired, but in poorer health condition. They access the portal more frequently, indicating that they are potentially more involved in managing their health. Using fixed-effects logistic regression models to compare across practices, we note that practice indicator is a significant predictor of eVisit usage, perhaps due to the varying strategies used to build awareness and encourage adoption. Despite the small difference in out-of-pocket payment for eVisits covered by insurance vs. otherwise, insurance coverage for eVisits significantly contributes to increased usage. In ongoing work, additional characteristics of patients and practices that have access to the patient portal will be used to better delineate patients’ choice of eVisit vs. the traditional office visit. PMID:22195168

  12. Who are portal users vs. early e-Visit adopters? A preliminary analysis.

    PubMed

    Jung, C; Padman, R; Shevchik, G; Paone, S

    2011-01-01

    Patient portals and eVisits are gaining momentum due to increasing consumer demand for improved access to clinical information and services, availability of new technologies to deploy them and development of reimbursement initiatives by major payers. Despite increasing interest in online health consultation by consumers, adoption has been slow and little is known about the users of such services. In this study, we analyze the key features that distinguish early adopters of eVisits from portal consumers, in aggregate and in four distinct ambulatory practices, using data from a major healthcare provider in Western Pennsylvania. Preliminary results indicate that out of 10,532 portal users, the 336 patients who submitted 446 eVisits between April 1, 2009 and May 31, 2010 are younger on average, predominantly female, not retired, but in poorer health condition. They access the portal more frequently, indicating that they are potentially more involved in managing their health. Using fixed-effects logistic regression models to compare across practices, we note that practice indicator is a significant predictor of eVisit usage, perhaps due to the varying strategies used to build awareness and encourage adoption. Despite the small difference in out-of-pocket payment for eVisits covered by insurance vs. otherwise, insurance coverage for eVisits significantly contributes to increased usage. In ongoing work, additional characteristics of patients and practices that have access to the patient portal will be used to better delineate patients' choice of eVisit vs. the traditional office visit. PMID:22195168

  13. Spectroscopic Low Coherence Interferometry

    NASA Astrophysics Data System (ADS)

    Bosschaart, Nienke; van Leeuwen, T. G.; Aalders, Maurice C.; Hermann, Boris; Drexler, Wolfgang; Faber, Dirk J.

    Low-coherence interferometry (LCI) allows high-resolution volumetric imaging of tissue morphology and provides localized optical properties that can be related to the physiological status of tissue. This chapter discusses the combination of spatial and spectroscopic information by means of spectroscopic OCT (sOCT) and low-coherence spectroscopy (LCS). We describe the theory behind these modalities for the assessment of spatially resolved optical absorption and (back)scattering coefficient spectra. These spectra can be used for the highly localized quantification of chromophore concentrations and assessment of tissue organization on (sub)cellular scales. This leads to a wealth of potential clinical applications, ranging from neonatology for the determination of billibrubin concentrations, to oncology for the optical assessment of the aggressiveness of a cancerous lesion.

  14. Spectroscopic Binary Stars

    NASA Astrophysics Data System (ADS)

    Batten, A.; Murdin, P.

    2000-11-01

    Historically, spectroscopic binary stars were binary systems whose nature was discovered by the changing DOPPLER EFFECT or shift of the spectral lines of one or both of the component stars. The observed Doppler shift is a combination of that produced by the constant RADIAL VELOCITY (i.e. line-of-sight velocity) of the center of mass of the whole system, and the variable shift resulting from the o...

  15. Spectroscopically Unlocking Exoplanet Characteristics

    NASA Astrophysics Data System (ADS)

    Lewis, Nikole

    2016-05-01

    Spectroscopy plays a critical role in a number of areas of exoplanet research. The first exoplanets were detected by precisely measuring Doppler shifts in high resolution (R ~ 100,000) stellar spectra, a technique that has become known as the Radial Velocity (RV) method. The RV method provides critical constraints on exoplanet masses, but is currently limited to some degree by robust line shape predictions. Beyond the RV method, spectroscopy plays a critical role in the characterization of exoplanets beyond their mass and radius. The Hubble Space Telescope has spectroscopically observed the atmospheres of exoplanets that transit their host stars as seen from Earth giving us key insights into atmospheric abundances of key atomic and molecular species as well as cloud optical properties. Similar spectroscopic characterization of exoplanet atmospheres will be carried out at higher resolution (R ~ 100-3000) and with broader wavelength coverage with the James Webb Space Telescope. Future missions such as WFIRST that seek to the pave the way toward the detection and characterization of potentially habitable planets will have the capability of directly measuring the spectra of exoplanet atmospheres and potentially surfaces. Our ability to plan for and interpret spectra from exoplanets relies heavily on the fidelity of the spectroscopic databases available and would greatly benefit from further laboratory and theoretical work aimed at optical properties of atomic, molecular, and cloud/haze species in the pressure and temperature regimes relevant to exoplanet atmospheres.

  16. Technology Performance Exchange (Fact Sheet)

    SciTech Connect

    Not Available

    2012-10-01

    This fact sheet, 'The Technology Performance Exchange' will be presented at the ET Summit, held at the Pasadena Convention Center on October 15-17, 2012. The Technology Performance Exchange will be a centralized, Web-based portal for finding and sharing energy performance data for commercial building technologies.

  17. Design and Implementation of a Portal for the Medical Equipment Market: MEDICOM

    PubMed Central

    Kalivas, Dimitris; Panou-Diamandi, Ourania; Zeelenberg, Cees; van Nimwegen, Chris

    2001-01-01

    Management Systems are used for the system's databases. The end-user interface is implemented using HTML, Javascript, Java applets, and XML documents. Communication between the Portal and the manufacturers' servers is implemented using a CORBA interface. Remote administration of the Portal is enabled by dynamically-generated HTML interfaces based on XML documents. A representative group of users evaluated the system. The aim of the evaluation was validation of the usability of all of MEDICOM's functionality. The evaluation procedure was based on ISO/IEC 9126 Information technology - Software product evaluation - Quality characteristics and guidelines for their use. Results The overall user evaluation of the MEDICOM system was very positive. The MEDICOM system was characterized as an innovative concept that brings significant added value to medical-equipment commerce. Conclusions The eventual benefits of the MEDICOM system are (a) establishment of a worldwide-accessible marketplace between manufacturers and health care professionals that provides up-to-date and high-quality product information in an easy and friendly way and (b) enhancement of the efficiency of marketing procedures and after-sales support. PMID:11772547

  18. Spectroscopic lidar technology for small space apparatus

    NASA Astrophysics Data System (ADS)

    Matvienko, Gennadii G.; Ponomarev, Yurii N.; Romanovskii, Oleg A.; Ptashnik, Igor V.

    2002-01-01

    The development of the techniques for spaceborne detecting gas anomalies in the lower atmosphere is very important. The results of the Kioto protocol, an extended use of hydrocarbon raw material, the occurrence of new chemical emissions call for further realization of global control over gaseous contaminations in the atmosphere. A spaceborne location of sensors is very promising for solving this problem. In this case the light automatic satellites, oriented to a limited area of application, are the most promising. As a rule, for such satellites the orbits at 500 km altitude and more are selected. This altitude and small mass of a satellite impose severe requirements on the efficiency of the techniques and apparatus realizations. Taking account of the last-named fact, the paper describes the use of the differential absorption method with a reflection from the Earth's surface for global monitoring of gaseous contaminations. The experiments were performed to assess lidar detection of ground anomalies of hydrocarbons in the 3-5 micrometers transmittance window. It is shown that, as applied to a spaceborne platform MKA- 200, this technique provides for localization of the background concentration excess of gases of hydrocarbon cycle with an error from 15% to 25%.

  19. Instructions for Uploading Data to the Assay Portal - Instructions for Uploading Data to the Assay Portal

    Cancer.gov

    This document provides instructions for configuring and uploading data files to the CPTAC Assay Portal. It is divided into sections, with an overview checklist provided at the end. If help is needed at any stage of the process, please use the support page: https://assays.cancer.gov/support/

  20. 29 CFR 785.24 - Principles noted in Portal-to-Portal Bulletin.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Section 785.24 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... regarded as work and as compensable under the Fair Labor Standards Act, remain so under the Portal Act... of Principles Preparatory and Concluding Activities § 785.24 Principles noted in...

  1. Open source portal to distributed image repositories

    NASA Astrophysics Data System (ADS)

    Tao, Wenchao; Ratib, Osman M.; Kho, Hwa; Hsu, Yung-Chao; Wang, Cun; Lee, Cason; McCoy, J. M.

    2004-04-01

    In large institution PACS, patient data may often reside in multiple separate systems. While most systems tend to be DICOM compliant, none of them offer the flexibility of seamless integration of multiple DICOM sources through a single access point. We developed a generic portal system with a web-based interactive front-end as well as an application programming interface (API) that allows both web users and client applications to query and retrieve image data from multiple DICOM sources. A set of software tools was developed to allow accessing several DICOM archives through a single point of access. An interactive web-based front-end allows user to search image data seamlessly from the different archives and display the results or route the image data to another DICOM compliant destination. An XML-based API allows other software programs to easily benefit from this portal to query and retrieve image data as well. Various techniques are employed to minimize the performance overhead inherent in the DICOM. The system is integrated with a hospital-wide HIPAA-compliant authentication and auditing service that provides centralized management of access to patient medical records. The system is provided under open source free licensing and developed using open-source components (Apache Tomcat for web server, MySQL for database, OJB for object/relational data mapping etc.). The portal paradigm offers a convenient and effective solution for accessing multiple image data sources in a given healthcare enterprise and can easily be extended to multi-institution through appropriate security and encryption mechanisms.

  2. Quantum cascade laser-based screening portal for the detection of explosive precursors

    NASA Astrophysics Data System (ADS)

    Lindley, Ruth; Normand, Erwan; Howieson, Iain; McCulloch, Michael; Black, Paul; Lewis, Colin; Foulger, Brian

    2007-10-01

    In recent years, quantum cascade lasers (QCL) have been proven in robust, high-performance gas analyzers designed for continuous emission monitoring (CEM) in harsh environments. In 2006, Cascade Technologies reported progress towards adapting its patented technology for homeland security applications by publishing initial results on explosive compound detection. This paper presents the performance and results from a QCL-based people screening portal developed during the past year and aimed at the detection of precursors used in the make up of improvised explosive devices (IED). System tests have been carried out on a large number of potential interferents, together with target precursor materials, reinforcing original assumptions that compound fingerprinting can be effectively demonstrated using this technique. Results have shown that an extremely high degree of specificity can be achieved with a sub-second response time. Furthermore, it has been shown that unambiguous precursor signature recognition can be extended to compound mixtures associated with the intermediate stages in the make up of IEDs, whilst maintaining interferent immunity. The portal sensitivity was configured for parts per billion (ppb) detection level thresholds, but is currently being reconfigured for sub-ppb detection. In summary, the results obtained from the QCL based portal indicate that development of a low cost detection system, with enhanced features such as low false positive and high throughput screening of individuals or items, is possible. Development and testing was carried out with the support of the UK government.

  3. The NOAO NVO Portal: Overall Design & Implementation

    NASA Astrophysics Data System (ADS)

    Fuentes, E.; Miller, C. J.; Gasson, D.

    2007-10-01

    We present an overview and design of the NOAO National Virtual Observatory (NVO) Portal. This is a web application providing one-stop discovery, analysis, and access to VO-compliant imaging data and services. It strictly follows the Model-View-Controller (MVC) design pattern and relies heavily on Asynchronous Javascript And XML (AJAX) in the browser. Because of the heavy use of AJAX, the relatively simple database schemas, and, most importantly, the rapid development/iteration schedule, Ruby-on-Rails (RoR) was chosen as the implementation language and PostgreSQL as the database engine.

  4. [Pathology of liver cirrhosis and portal hypertension].

    PubMed

    Bläker, H; Theuer, D; Otto, H F

    2001-10-01

    Cirrhosis is a late stage finding in chronic liver diseases of different aetiology. It is defined morphologically as a diffuse process with the presence of fibrosis and structurally abnormal nodules. The consequences of cirrhosis are both, mechanical and functional. The mechanical complications result from intra- and extrahepatic shunting of blood and portal hypertension while the functional relevance bases upon a failure of liver cells to perform their physiological role in metabolism, synthesis and secretion. Beside these complications that are directly linked to liver function cirrhosis in itself is a risk factor for hepatocellular carcinoma. PMID:11715574

  5. Barriers and Facilitators to Online Portal Use Among Patients and Caregivers in a Safety Net Health Care System: A Qualitative Study

    PubMed Central

    Sarkar, Urmimala; Schillinger, Dean; Ralston, James D; Ratanawongsa, Neda; Pasick, Rena; Lyles, Courtney R

    2015-01-01

    Background Patient portals have the potential to support self-management for chronic diseases and improve health outcomes. With the rapid rise in adoption of patient portals spurred by meaningful use incentives among safety net health systems (a health system or hospital providing a significant level of care to low-income, uninsured, and vulnerable populations), it is important to understand the readiness and willingness of patients and caregivers in safety net settings to access their personal health records online. Objective To explore patient and caregiver perspectives on online patient portal use before its implementation at San Francisco General Hospital, a safety net hospital. Methods We conducted 16 in-depth interviews with chronic disease patients and caregivers who expressed interest in using the Internet to manage their health. Discussions focused on health care experiences, technology use, and interest in using an online portal to manage health tasks. We used open coding to categorize all the barriers and facilitators to portal use, followed by a second round of coding that compared the categories to previously published findings. In secondary analyses, we also examined specific barriers among 2 subgroups: those with limited health literacy and caregivers. Results We interviewed 11 patients and 5 caregivers. Patients were predominantly male (82%, 9/11) and African American (45%, 5/11). All patients had been diagnosed with diabetes and the majority had limited health literacy (73%, 8/11). The majority of caregivers were female (80%, 4/5), African American (60%, 3/5), caregivers of individuals with diabetes (60%, 3/5), and had adequate health literacy (60%, 3/5). A total of 88% (14/16) of participants reported interest in using the portal after viewing a prototype. Major perceived barriers included security concerns, lack of technical skills/interest, and preference for in-person communication. Facilitators to portal use included convenience, health

  6. Palliative Portal Vein Stent Placement in Malignant and Symptomatic Extrinsic Portal Vein Stenosis or Occlusion

    SciTech Connect

    Novellas, Sebastien; Denys, Alban Bize, Pierre; Brunner, Philippe; Motamedi, Jean Paul; Gugenheim, Jean; Caroli, Francois-Xavier; Chevallier, Patrick

    2009-05-15

    This article evaluates the results of portal vein (PV) stent placement in patients with malignant extrinsic lesions stenosing or obstructing the PV and causing symptomatic PV hypertension (PVHT). Fourteen patients with bile duct cancer (n = 7), pancreatic adenocarcinoma (n = 4), or another cancer (n = 3) underwent percutaneous transhepatic portal venous stent placement because of gastroesophageal or jejunal varices (n = 9), ascites (n = 7), and/or thrombocytopenia (n = 2). Concurrent tumoral obstruction of the main bile duct was treated via the transhepatic route in the same session in four patients. Changes in portal venous pressure, complications, stent patency, and survival were evaluated. Mean {+-} standard deviation (SD) gradient of portal venous pressure decreased significantly immediately after stent placement from 11.2 mmHg {+-} 4.6 to 1.1 mmHg {+-} 1.0 (P < 0.00001). Three patients had minor complications, and one developed a liver abscess. During a mean {+-} SD follow-up of 134.4 {+-} 123.3 days, portal stents remained patent in 11 patients (78.6%); stent occlusion occurred in 3 patients, 2 of whom had undergone previous major hepatectomy. After stent placement, PVHT symptoms were relieved in four (57.1%) of seven patients who died (mean survival, 97 {+-} 71.2 days), and relieved in six (85.7%) of seven patients still alive at the end of follow-up (mean follow-up, 171.7 {+-} 153.5 days). Stent placement in the PV is feasible and relatively safe. It helped to relieve PVHT symptoms in a single session.

  7. THE NSF National Science, Technology, Engineering, and Mathematics Education Digital Library (NSDL) Program; Software for Building a Full-Featured Discipline-Based Web Portal; A Metadata Framework Developed at the Tsinghua University Library To Aid in the Preservation of Digital Resources; A Scalable Architecture for Harvest-Based Digital Libraries; The Design and Evaluation of Interactivities in a Digital Library.

    ERIC Educational Resources Information Center

    Zia, Lee L.; Almasy, Edward; Sleasman, David; Bower, Rachael; Niu, Jingfang; Liu, Xiaoming; Maly, Kurt; Zubair, Mohammad; Nelson, Michael L.; Brody, Tim; Harnard, Stevan; Carr, Les; Budhu, Muniram; Coleman, Anita

    2002-01-01

    Includes five articles that discuss digital library programs related to the National Science Foundation; software for building Web portals; metadata developed at Tsinghua University Library (China) for preserving digital resources; the Open Archives Initiative for metadata and the need for a common infrastructure; and interactivity in a digital…

  8. Monte Carlo simulation and experimental measurement of a nonspectroscopic radiation portal monitor for photon detection efficiencies of internally deposited radionuclides

    NASA Astrophysics Data System (ADS)

    Carey, Matthew Glen

    Particle transport of radionuclide photons using the Monte Carlo N-Particle computer code can be used to determine a portal monitor's photon detection efficiency, in units of counts per photon, for internally deposited radionuclides. Good agreement has been found with experimental results for radionuclides that emit higher energy photons, such as Cs-137 and Co-60. Detection efficiency for radionuclides that emit lower energy photons, such as Am-241, greatly depend on the effective discriminator energy level of the portal monitor as well as any attenuating material between the source and detectors. This evaluation uses a chi-square approach to determine the best fit discriminator level of a non-spectroscopic portal monitor when the effective discriminator level, in units of energy, is not known. Internal detection efficiencies were evaluated experimentally using an anthropomorphic phantom with NIST traceable sources at various internal locations, and by simulation using MCNP5. The results of this research find that MCNP5 can be an effective tool for simulation of photon detection efficiencies, given a known discriminator level, for internally and externally deposited radionuclides. In addition, MCNP5 can be used for bounding personnel doses from either internally or externally deposited mixtures of radionuclides.

  9. Constriction rate variation produced by partial ligation of the portal vein at pre-hepatic portal hypertension induced in rats

    PubMed Central

    RODRIGUES, Daren Athiê Boy; da SILVA, Aline Riquena; SERIGIOLLE, Leonardo Carvalho; FIDALGO, Ramiro de Sousa; FAVERO, Sergio San Gregorio; LEME, Pedro Luiz Squilacci

    2014-01-01

    Background Partial portal vein ligation causes an increase in portal pressure that remains stable even after the appearance of collateral circulation, with functional adaptation to prolonged decrease in portal blood flow. Aim To assess whether different constriction rates produced by partial ligation of the vein interfere with the results of this experimental model in rats. Methods Three groups of five rats each were used; in group 1 (sham-operated), dissection and measurement of portal vein diameters were performed. Portal hypertension was induced by partial portal vein ligation, reducing its size to 0.9 mm in the remaining 10 animals, regardless of the initial diameter of the veins. Five animals with portal hypertension (group 2) underwent reoperation after 15 days and the rats in group 3 after 30 days. The calculation of the constriction rate was performed using a specific mathematical formula (1 - π r 2 / π R2) x 100% and the statistical analysis with the Student t test. Results The initial diameter of the animal's portal vein was 2.06 mm, with an average constriction rate of the 55.88%; although the diameter of the veins and the constriction rate in group 2 were lower than in group 3 (2.06 mm - 55,25% and 2.08 mm - 56.51%, respectively), portal hypertension was induced in all rats and no significant macroscopic differences were found between the animals that were reoperated after 15 days and after 30 days respectively, being the shorter period considered enough for the evaluation. Comparing the initial diameter of the vein and the rate of constriction performed in groups 2 and 3, no statistic significance was found (p>0.05). Conclusion Pre-hepatic portal hypertension in rat can be induced by the reduction of the portal vein diameter to 0.9 mm, regardless the initial diameter of the vein and the vessel constriction rate. PMID:25626939

  10. Highly efficient integration of the viral portal proteins from different types of phages into planar bilayers for the black lipid membrane analysis.

    PubMed

    Jing, Peng; Paraiso, Hallel; Burris, Benjamin

    2016-02-01

    The planar lipid bilayer technology is a technique that yields incredibly useful structural function information about a single channel protein. It is also currently actively utilized as a powerful platform using biological protein nanopores for the development of single-molecule nanopore sensing technology, as well as ultrafast DNA sequencing technology. The portal protein, GP10, from the bacteriophage Φ29 was the first phage portal protein shown to be successfully inserted into planar bilayer membranes, thereby it may inspire more researchers to apply the techniques to portal proteins from the other bacteriophages. However, the technology is far from perfect since the insertion of the channel proteins into planar bilayer membranes is not only technically difficult but also time-consuming. For the fusion of phage portal proteins, vesicles are typically needed to be reconstituted with the portal proteins to form proteoliposomes. However, most of the phage portal proteins have low solubility, and may self-aggregate during the preparation of the proteoliposomes. Furthermore, the fusion of the formed proteoliposomes is sporadic, unpredictable and varied from person to person. Due to the lack of experimental consistency between labs, the results from different methodologies reported for generating fusible proteoliposomes are highly variable. In this research, we propose a new method for the preparation of the fusible proteoliposomes containing portal proteins from bacteriophages, to circumvent the problems aforementioned. Compared to the conventional methods, this method was able to avoid the protein aggregation issues during the vesicle preparation by eliminating the need for detergents and the subsequent time-consuming step for detergent removal. The proteoliposomes prepared by the method were shown to be more efficiently and rapidly inserted into planar bilayer membranes bathed in different conducting buffer solutions including those with nonelectrolytes such as

  11. Promoting scientific collaboration and research through integrated social networking capabilities within the OpenTopography Portal

    NASA Astrophysics Data System (ADS)

    Nandigam, V.; Crosby, C. J.; Baru, C.

    2009-04-01

    LiDAR (Light Distance And Ranging) topography data offer earth scientists the opportunity to study the earth's surface at very high resolutions. As a result, the popularity of these data is growing dramatically. However, the management, distribution, and analysis of community LiDAR data sets is a challenge due to their massive size (multi-billion point, mutli-terabyte). We have also found that many earth science users of these data sets lack the computing resources and expertise required to process these data. We have developed the OpenTopography Portal to democratize access to these large and computationally challenging data sets. The OpenTopography Portal uses cyberinfrastructure technology developed by the GEON project to provide access to LiDAR data in a variety of formats. LiDAR data products available range from simple Google Earth visualizations of LiDAR-derived hillshades to 1 km2 tiles of standard digital elevation model (DEM) products as well as LiDAR point cloud data and user generated custom-DEMs. We have found that the wide spectrum of LiDAR users have variable scientific applications, computing resources and technical experience and thus require a data system with multiple distribution mechanisms and platforms to serve a broader range of user communities. Because the volume of LiDAR topography data available is rapidly expanding, and data analysis techniques are evolving, there is a need for the user community to be able to communicate and interact to share knowledge and experiences. To address this need, the OpenTopography Portal enables social networking capabilities through a variety of collaboration tools, web 2.0 technologies and customized usage pattern tracking. Fundamentally, these tools offer users the ability to communicate, to access and share documents, participate in discussions, and to keep up to date on upcoming events and emerging technologies. The OpenTopography portal achieves the social networking capabilities by integrating various

  12. 3. East portal of Tunnel 39, view to west with ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. East portal of Tunnel 39, view to west with east portal of Tunnel 38 (HAER CA-211) visible in distance, 135mm lens with electronic flash fill. - Central Pacific Transcontinental Railroad, Tunnel No. 39, Milepost 180.95, Cisco, Placer County, CA

  13. MedEdPORTAL: Educational Scholarship for Teaching

    ERIC Educational Resources Information Center

    Reynolds, Robby J.; Candler, Christopher S.

    2008-01-01

    MedEdPORTAL is an online publication service provided at no charge by the Association of American Medical Colleges (AAMC). The intent is to promote collaboration and educational scholarship by helping educators publish and share educational resources. With MedEdPORTAL, users can quickly locate high-quality, peer-reviewed teaching materials in both…

  14. Westfacing portals within Open Cut No. 2 (South Bergen Tunnel ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    West-facing portals within Open Cut No. 2 (South Bergen Tunnel on right, North Bergen Tunnel see HAER No. NJ-136) on left), from within the opposite portal of the South Bergen Tunnel, looking east - Delaware, Lackawanna & Western Railroad, South Bergen Tunnel, Jersey City, Hudson County, NJ

  15. An Analysis of Knowledge Management Mechanisms in Healthcare Portals

    ERIC Educational Resources Information Center

    Lee, Chei Sian; Goh, Dion Hoe-Lian; Chua, Alton Y. K.

    2010-01-01

    Healthcare portals are becoming increasingly popular with Internet users since they play an important role in supporting interaction between individuals and healthcare organizations with a Web presence. Additionally, many of these organizations make use of knowledge management mechanisms on their healthcare portals to manage the abundance of…

  16. 2. West portal of Tunnel 18, oblique view to northnortheast, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. West portal of Tunnel 18, oblique view to north-northeast, 135mm lens. Note the use of concrete face and wingwalls, with dressed stone voussoirs, wingwall coping, parapet with stone belt course and coping, and coursed stone masonry slope protection flanking the portal. - Southern Pacific Railroad Natron Cutoff, Tunnel No. 18, Milepost 410, Dorris, Siskiyou County, CA

  17. Connections: A Comprehensive Student Portal. Concept Paper and Proposal.

    ERIC Educational Resources Information Center

    Harr, Gary Lynn

    A student Web portal is a personalized, student-centric view of College Web resources. The "Artemis" system at Florida Community College at Jacksonville (FCCJ), represents movement toward realization of the efficiencies and student service possibilities of a Web portal. This proposal recommends a radical expansion of Artemis functions, one that…

  18. North portal and deck view, from north, showing inclined endposts, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    North portal and deck view, from north, showing inclined endposts, Pratt through trusses, north portal strut, overhead bracing, pipe rails and posts, and concrete deck with bituminous wearing surface - Castle Garden Bridge, Township Route 343 over Bennetts Branch of Sinnemahoning Creek, Driftwood, Cameron County, PA

  19. South portal and deck view from south, showing inclined endposts, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    South portal and deck view from south, showing inclined endposts, Pratt through trusses, south portal strut, overhead bracing, pipe rails and posts, and concrete deck with bituminous wearing surface - Castle Garden Bridge, Township Route 343 over Bennetts Branch of Sinnemahoning Creek, Driftwood, Cameron County, PA

  20. 1. West portal of Tunnel 35, contextual view to eastnortheast ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. West portal of Tunnel 35, contextual view to east-northeast with west portal of Tunnel 36 (HAER CA-209) visible in distance at left, 135mm lens. - Central Pacific Transcontinental Railroad, Tunnel No. 35, Milepost 176.62, Yuba Pass, Nevada County, CA

  1. 8. FIGUEROA STREET TUNNEL NO. 2, SOUTH PORTAL SEEN FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. FIGUEROA STREET TUNNEL NO. 2, SOUTH PORTAL SEEN FROM ABOVE NORTH PORTAL OF TUNNEL NO. 3. LOOKING 12°N. - Figueroa Street Tunnels, Mileposts 24.90, 25.14, 25.28, & 25.37 on Arroyo Seco Parkway, Los Angeles, Los Angeles County, CA

  2. 6. East portal of Tunnel 17, oblique view to westsouthwest, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. East portal of Tunnel 17, oblique view to west-southwest, 90mm lens. This view shows to advantage the stepped concrete wingwalls and fitted stone masonry coping protection flanking the portal, features typical of the Southern Pacific Common Standard tunnels of this period. - Southern Pacific Railroad Natron Cutoff, Tunnel No. 17, Milepost 408, Dorris, Siskiyou County, CA

  3. 1. West portal of Tunnel 38, contextual view to east, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. West portal of Tunnel 38, contextual view to east, 135mm lens. West portal of Tunnel 3 (HAER CA-212) on original Central Pacific Transcontinental line visible in distance at left. - Central Pacific Transcontinental Railroad, Tunnel No. 38, Milepost 180.58, Cisco, Placer County, CA

  4. 1. West portal of Tunnel 39, contextual view to east, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. West portal of Tunnel 39, contextual view to east, 135mm lens. West portal of Tunnel 4 (HAER CA-214) on the original Central Pacific Transcontinental line is visible at left. - Central Pacific Transcontinental Railroad, Tunnel No. 39, Milepost 180.95, Cisco, Placer County, CA

  5. 6. East portal of Tunnel 18, oblique view to northwest, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. East portal of Tunnel 18, oblique view to northwest, 135mm lens. This view shows to advantage the stepped ashlar granite wingwalls and fitted rubble slab slope protection flanking the portal, features typical of the Southern Pacific Common Standard tunnels. - Central Pacific Transcontinental Railroad, Tunnel No. 18, Milepost 120.5, Newcastle, Placer County, CA

  6. 1. West portal of Tunnel 27 in distance, contextual view ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. West portal of Tunnel 27 in distance, contextual view to northeast looking past Tunnel 26 (HAER CA-202) from atop east portal of Tunnel 25 (HAER CA-201), 380mm lens. - Central Pacific Transcontinental Railroad, Tunnel No. 27, Milepost 133.9, Applegate, Placer County, CA

  7. Continued Use of a Chinese Online Portal: An Empirical Study

    ERIC Educational Resources Information Center

    Shih, Hung-Pin

    2008-01-01

    The evolution of the internet has made online portals a popular means of surfing the internet. In internet commerce, understanding the post-adoption behaviour of users of online portals can help enterprises to attract new users and retain existing customers. For predicting continued use intentions, this empirical study focused on applying and…

  8. Teachers' Acceptance and Use of an Educational Portal

    ERIC Educational Resources Information Center

    Pynoo, Bram; Tondeur, Jo; van Braak, Johan; Duyck, Wouter; Sijnave, Bart; Duyck, Philippe

    2012-01-01

    In this study, teachers' acceptance and use of an educational portal is assessed based on data from two sources: usage data (number of logins, downloads, uploads, reactions and pages viewed) and an online acceptance questionnaire. The usage data is extracted on two occasions from the portal's database: at survey completion (T1) and twenty-two…

  9. Measuring Campus Portal Effectiveness and the Contributing Factors

    ERIC Educational Resources Information Center

    Masrek, Mohamad Noorman bin

    2007-01-01

    Purpose: The purpose of the paper is to evaluate the effectiveness or success of universities' portal implementation from the perspective of students as users. Adopting the model developed by Delone and McLean, portal effectiveness is defined as being composed of information quality, systems quality and service quality. In addition, the paper also…

  10. [Aspects of pathogenetc pharmacotherapy for portal hypertension in liver cirrhosis].

    PubMed

    Garbuzenko, D V

    2016-01-01

    The review of literature considers the principles of medical treatment for portal hypertension in liver cirrhosis, which are based on the current views of its development mechanisms. It describes both current pharmacotherapy methods for portal hypertension and drugs, the efficacy of which is being investigated. PMID:27135108

  11. Portal: Your Door to World Languages and Cultures

    ERIC Educational Resources Information Center

    Elliott, Don; Lawton, Rachele

    2009-01-01

    Portal: Your Door to World Languages and Cultures was a series of public cultural events, in a variety of formats, created through a new partnership between the credit and continuing education (noncredit) foreign language programs at the Community College of Baltimore County (CCBC). Portal was designed to cultivate interest in foreign languages…

  12. 3. VIEW SOUTHEAST VIEW OF EAST PORTAL SHOWING SKEW AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. VIEW SOUTHEAST- VIEW OF EAST PORTAL SHOWING SKEW AND PORTAL BRACING. - National Docks Branch Bridge N.D.2F, Spans former Central Railroad of New Jersey , west of New Jersey Turnpike, north of Communipaw Avenue near Johnson Avenue, Jersey City, Hudson County, NJ

  13. Spectroscopic survey of LAMOST

    NASA Astrophysics Data System (ADS)

    Zhao, Yongheng

    2014-07-01

    LAMOST is a special reflecting Schmidt telescope. LAMOST breaks through the bottleneck of the large scale spectroscopic survey observation with both large aperture (effective aperture of 3.6 - 4.9m) and wide field of view (5 degrees). It is an innovative active reflecting Schmidt configuration achieved by changing mirror surface continuously to achieve a series different reflecting Schmidt system in different moments. By using the parallel controllable fiber positioning technique, the focal surface of 1.75 meters in diameter accommodates 4000 optical fibers. Also, LAMOST has 16 spectrographs with 32 CCD cameras. LAMOST is the telescope of the highest spectrum acquiring rate. As a national large scientific project, LAMOST project was proposed formally in 1996. The construction was started in 2001 and completed in 2008. After commission period, LAMOST pilot survey was started in October 2011 and spectroscopic survey began in September 2012. From October 2011 to June 2013, LAMOST has obtained more than 2 million spectra of celestial objects. There are 1.7 million spectra of stars, in which the stellar parameters (effective temperature, surface gravity, metalicitiy and radial velocity) of more than 1 million stars was obtained. In the first period of spectroscopic survey of LAMOST, 5 million of stellar spectra will be obtained and will make substantial contribution to the study of the stellar astrophysics and the structure of the Galaxy, such as the spheroid substructure of the Galaxy, the galactic gravitational potential and the distribution of the dark matter in the Galaxy, the extremely metal poor stars and hypervelocity stars, the 3D extinction in the Galaxy, the structure of thin and thick disks of the Galaxy, and so on.

  14. Stent Recanalization of Chronic Portal Vein Occlusion in a Child

    SciTech Connect

    Cwikiel, Wojciech; Solvig, Jan; Schroder, Henrik

    2000-07-15

    An 8-year-old boy with a 21/2 year history of portal hypertension and repeated bleedings from esophageal varices, was referred for treatment. The 3.5-cm-long occlusion of the portal vein was passed and the channel created was stabilized with a balloon-expandable stent; a portosystemic stent-shunt was also created. The portosystemic shunt closed spontaneously within 1 month, while the recanalized segment of the portal vein remained open. The pressure gradient between the intrahepatic and extrahepatic portal vein branches dropped from 17 mmHg to 0 mmHg. The pressure in the portal vein dropped from 30 mmHg to 17 mmHg and the bleedings stopped. The next dilation of the stent was performed 12 months later due to an increased pressure gradient; the gastroesophageal varices disappeared completely. Further dilation of the stent was planned after 2, 4, and 6 years.

  15. A Web portal for CMS Grid job submission and management

    NASA Astrophysics Data System (ADS)

    Braun, David; Neumeister, Norbert

    2010-04-01

    We present a Web portal for CMS Grid submission and management. The portal is built using a JBoss application server. It has a three tier architecture; presentation, business logic and data. Bean based business logic interacts with the underlying Grid infrastructure and pre-existing external applications, while the presentation layer uses AJAX to offer an intuitive, functional interface to the back-end. Application data aggregating information from the portal as well as the external applications is persisted to the server memory cache and then to a backend database. We describe how the portal exploits standard, off-the-shelf commodity software together with existing Grid infrastructures in order to facilitate job submission and monitoring for the CMS collaboration. This paper describes the design, development, current functionality and plans for future enhancements of the portal.

  16. Advances in the treatment of portal hypertension in cirrhosis.

    PubMed

    Kimer, N; Wiese, S; Mo, S; Møller, S; Bendtsen, F

    2016-08-01

    Non-selective beta-blockers and handling of esophageal varices has been key elements in the treatment of portal hypertension in recent decades. Liver vein catheterization has been essential in diagnosis and monitoring of portal hypertension, but ongoing needs for noninvasive tools has led to research in areas of both biomarkers, and transient elastography, which displays promising results in discerning clinically significant portal hypertension. Novel research into the areas of hepatic stellate cell function and the dynamic components of portal hypertension has revealed promising areas of treatment modalities, targeting intestinal decontamination, angiogenesis, inflammation and oxidative stress. Future studies may reveal if these initiatives lead to developments of new drugs for treatment of portal hypertension. PMID:26982499

  17. The Cosmos Portal and the IYA2009 Project

    NASA Astrophysics Data System (ADS)

    Haisch, Bernard M.; Sims, M.; Lindblom, J.

    2009-01-01

    In 2007 the non-profit Digital Universe Foundation (DUF) launched the Earth Portal as a comprehensive resource for timely, objective, science-based information about the environment. There are currently over 1000 scholars from 60 countries engaged in this rapidly growing web-based collaboration. The Cosmos Portal is the second major DUF initiative (digitaluniverse.net/cosmos). In support of the IYA2009 effort, the Cosmos Portal is recruiting astronomy professionals to make use of easy online tools to publish articles, blogs, news items, image galleries, class notes, lectures, powerpoint presentations, links to other high quality websites or other educational material. In parallel we intend to bring hundreds of amateur astronomy organizations and thousands of amateur astronomers and telescope makers together in a community of portals (digitaluniverse.net/cosmoscommunity). This will allow vibrant online collaboration and information sharing. We encourage you to start a portal on your favorite topic or join an existing topic as a contributor.

  18. Portal Hypertension as Immune Mediate Disease

    PubMed Central

    Manti, Sara; Marseglia, Lucia; D'Angelo, Gabriella; Filippelli, Martina; Cuppari, Caterina; Gitto, Eloisa; Romano, Claudio; Arrigo, Teresa; Salpietro, Carmelo

    2014-01-01

    Context: Portal Hypertension (PH) is a progressive complication due to chronic liver disease. In addition to pathophysiologic changes in the micro-circulation, in PH are established fibrous tissue (periportal fibrous septal) and regenerative hyperplastic nodules (from micro- to macro-nodules) promoting hepatic architectural distortion. Evidence Acquisition: A literature search of electronic databases was undertaken for the major studies published from 1981 to today. The databases searched were: PubMed, EMBASE, Orphanet, Midline and Cochrane Library. We used the keywords: "portal hypertension, children, immune system, endocrine system, liver fibrosis". Results: It is believed that PH results from three “phenotype”: ischemia-reperfusion, involving nervous system (NS); edema and oxidative damage, involving immune system; inflammation and angiogenesis, involving endocrine system. However, its exact cause still underdiagnosed and unknown. Conclusions: PH is a dynamic and potentially reversible process. Researchers have tried to demonstrate mechanisms underlying PH and its related-complications. This review focuses on the current knowledge regarding the pathogenesis, and immune, endocrine-metabolic factors of disease. The strong positive association between immune system and development of PH could be efficient to identify non-invasive markers of disease, to modify prognosis of PH, and to development and application of specific and individual anti-inflammatory therapy. PMID:24976841

  19. Management of rectal varices in portal hypertension

    PubMed Central

    Al Khalloufi, Kawtar; Laiyemo, Adeyinka O

    2015-01-01

    Rectal varices are portosystemic collaterals that form as a complication of portal hypertension, their prevalence has been reported as high as 94% in patients with extrahepatic portal vein obstruction. The diagnosis is typically based on lower endoscopy (colonoscopy or sigmoidoscopy). However, endoscopic ultrasonography has been shown to be superior to endoscopy in diagnosing rectal varices. Color Doppler ultrasonography is a better method because it allows the calculation of the velocity of blood flow in the varices and can be used to predict the bleeding risk in the varices. Although rare, bleeding from rectal varices can be life threatening. The management of patients with rectal variceal bleeding is not well established. It is important to ensure hemodynamic stability with blood transfusion and to correct any coagulopathy prior to treating the bleeding varices. Endoscopic injection sclerotherapy has been reported to be more effective in the management of active bleeding from rectal varices with less rebleeding rate as compared to endoscopic band ligation. Transjugular intrahepatic portsystemic shunt alone or in combination with embolization is another method used successfully in control of bleeding. Balloon-occluded retrograde transvenous obliteration is an emerging procedure for management of gastric varices that has also been successfully used to treat bleeding rectal varices. Surgical procedures including suture ligation and porto-caval shunts are considered when other methods have failed. PMID:26730278

  20. The Anatomy of a Grid portal

    NASA Astrophysics Data System (ADS)

    Licari, Daniele; Calzolari, Federico

    2011-12-01

    In this paper we introduce a new way to deal with Grid portals referring to our implementation. L-GRID is a light portal to access the EGEE/EGI Grid infrastructure via Web, allowing users to submit their jobs from a common Web browser in a few minutes, without any knowledge about the Grid infrastructure. It provides the control over the complete lifecycle of a Grid Job, from its submission and status monitoring, to the output retrieval. The system, implemented as client-server architecture, is based on the Globus Grid middleware. The client side application is based on a java applet; the server relies on a Globus User Interface. There is no need of user registration on the server side, and the user needs only his own X.509 personal certificate. The system is user-friendly, secure (it uses SSL protocol, mechanism for dynamic delegation and identity creation in public key infrastructures), highly customizable, open source, and easy to install. The X.509 personal certificate does not get out from the local machine. It allows to reduce the time spent for the job submission, granting at the same time a higher efficiency and a better security level in proxy delegation and management.

  1. Management of rectal varices in portal hypertension.

    PubMed

    Al Khalloufi, Kawtar; Laiyemo, Adeyinka O

    2015-12-28

    Rectal varices are portosystemic collaterals that form as a complication of portal hypertension, their prevalence has been reported as high as 94% in patients with extrahepatic portal vein obstruction. The diagnosis is typically based on lower endoscopy (colonoscopy or sigmoidoscopy). However, endoscopic ultrasonography has been shown to be superior to endoscopy in diagnosing rectal varices. Color Doppler ultrasonography is a better method because it allows the calculation of the velocity of blood flow in the varices and can be used to predict the bleeding risk in the varices. Although rare, bleeding from rectal varices can be life threatening. The management of patients with rectal variceal bleeding is not well established. It is important to ensure hemodynamic stability with blood transfusion and to correct any coagulopathy prior to treating the bleeding varices. Endoscopic injection sclerotherapy has been reported to be more effective in the management of active bleeding from rectal varices with less rebleeding rate as compared to endoscopic band ligation. Transjugular intrahepatic portsystemic shunt alone or in combination with embolization is another method used successfully in control of bleeding. Balloon-occluded retrograde transvenous obliteration is an emerging procedure for management of gastric varices that has also been successfully used to treat bleeding rectal varices. Surgical procedures including suture ligation and porto-caval shunts are considered when other methods have failed. PMID:26730278

  2. Software tool for portal dosimetry research.

    PubMed

    Vial, P; Hunt, P; Greer, P B; Oliver, L; Baldock, C

    2008-09-01

    This paper describes a software tool developed for research into the use of an electronic portal imaging device (EPID) to verify dose for intensity modulated radiation therapy (IMRT) beams. A portal dose image prediction (PDIP) model that predicts the EPID response to IMRT beams has been implemented into a commercially available treatment planning system (TPS). The software tool described in this work was developed to modify the TPS PDIP model by incorporating correction factors into the predicted EPID image to account for the difference in EPID response to open beam radiation and multileaf collimator (MLC) transmitted radiation. The processes performed by the software tool include; i) read the MLC file and the PDIP from the TPS, ii) calculate the fraction of beam-on time that each point in the IMRT beam is shielded by MLC leaves, iii) interpolate correction factors from look-up tables, iv) create a corrected PDIP image from the product of the original PDIP and the correction factors and write the corrected image to file, v) display, analyse, and export various image datasets. The software tool was developed using the Microsoft Visual Studio.NET framework with the C# compiler. The operation of the software tool was validated. This software provided useful tools for EPID dosimetry research, and it is being utilised and further developed in ongoing EPID dosimetry and IMRT dosimetry projects. PMID:18946980

  3. Amyloidosis: an unusual cause of portal hypertension

    PubMed Central

    Laborda, Lorena Silva; Bernardelli, Raquel; Pinesi, Henrique Trombini; Silva, Marilia Polo Minguete e; Chiavelli, Viviane; Simões, Angélica Braz; Felipe-Silva, Aloisio

    2016-01-01

    Amyloidosis comprises a group of diseases that occurs in five to nine cases per million patients per year worldwide irrespective of its classification. Although the hepatic involvement in primary amyloidosis is frequent, the clinical manifestations of liver amyloidosis are mild or even absent. The authors report the case of an aged man who complained of diffuse abdominal pain and marked weight loss and presented clinical signs of hepatopathy. Clinical workup revealed portal hypertension with ascites, hemorrhoids, and esophageal varices. The laboratory tests showed the cholestatic pattern of liver enzymes, hyperbilirubinemia, renal insufficiency and massive proteinuria accompanied by the presence of serum pike of monoclonal lambda light chain protein. The outcome was unfavorable, and the patient died. The autopsy findings revealed the diagnosis of amyloidosis predominantly involving the liver and kidneys. The bone marrow examination demonstrated the deposition of amyloid material associated with clonal plasma cells infiltration. The authors call attention to portal hypertension as a rare manifestation of primary amyloidosis. Meanwhile, this diagnosis should be taken into account whenever the hepatopathy is accompanied by laboratory abnormalities consistent with hepatic space-occupying lesions concomitantly with other organs involvement. In the case reported herein, kidney involvement was also present with renal failure, massive proteinuria with monoclonal serum gammopathy, what reinforced the diagnostic possibility of primary amyloidosis. PMID:27547738

  4. Hepatic myospherulosis complicating portal vein embolisation

    PubMed Central

    Lui, P C W; Luk, I S C; Lee, C K L; Lui, Y H; Leung, C Y; Choi, C H

    2004-01-01

    Aims: Myospherulosis is a rare condition characterised by sac-like structures containing spheroid bodies in cysts or cystic spaces in the tissue. This condition has not previously been reported in the liver. The association with previous portal vein embolisation using a mixture of butyl 2-cyanoacrylate and ethiodised oil and the proposed mechanism of pathogenesis are discussed. Methods: Samples from 8 patients treated by hepatectomy after portal vein embolisation using a mixture of butyl 2-cyanoacrylate and ethiodised oil were retrieved from the archives of the United Christian Hospital, Hong Kong. The histological specimens were reviewed. A panel of histochemical and immunohistochemical stains was used. Results: All cases showed hepatic myospherulosis within the veins. The veins were denuded of endothelium, which was replaced by granulation tissue and fibrous tissue with a lymphoplasmacytic infiltrate. Foreign body-type giant cells (six cases) and eosinophilic infiltrates (seven cases) were noted in most cases. Both parent bodies and endobodies were stained red by Papanicolaou and Masson’s trichrome and stained blue by solochrome cyanine. The endobodies showed immunoreactivity towards glycophorin A. They were negative for Alcian blue, periodic acid Schiff, Grocott, and Ziehl-Neelsen stains. Conclusions: The endobodies of myospherulosis may be misdiagnosed as fungi or algae by the unwary. The clinical history, intravascular location, lack of staining with periodic acid Schiff and Grocott stains, and positive glycophorin A staining are generally sufficient for a confident diagnosis of myospherulosis. PMID:14747440

  5. Amyloidosis: an unusual cause of portal hypertension.

    PubMed

    Takayasu, Vilma; Laborda, Lorena Silva; Bernardelli, Raquel; Pinesi, Henrique Trombini; Silva, Marilia Polo Minguete E; Chiavelli, Viviane; Simões, Angélica Braz; Felipe-Silva, Aloisio

    2016-01-01

    Amyloidosis comprises a group of diseases that occurs in five to nine cases per million patients per year worldwide irrespective of its classification. Although the hepatic involvement in primary amyloidosis is frequent, the clinical manifestations of liver amyloidosis are mild or even absent. The authors report the case of an aged man who complained of diffuse abdominal pain and marked weight loss and presented clinical signs of hepatopathy. Clinical workup revealed portal hypertension with ascites, hemorrhoids, and esophageal varices. The laboratory tests showed the cholestatic pattern of liver enzymes, hyperbilirubinemia, renal insufficiency and massive proteinuria accompanied by the presence of serum pike of monoclonal lambda light chain protein. The outcome was unfavorable, and the patient died. The autopsy findings revealed the diagnosis of amyloidosis predominantly involving the liver and kidneys. The bone marrow examination demonstrated the deposition of amyloid material associated with clonal plasma cells infiltration. The authors call attention to portal hypertension as a rare manifestation of primary amyloidosis. Meanwhile, this diagnosis should be taken into account whenever the hepatopathy is accompanied by laboratory abnormalities consistent with hepatic space-occupying lesions concomitantly with other organs involvement. In the case reported herein, kidney involvement was also present with renal failure, massive proteinuria with monoclonal serum gammopathy, what reinforced the diagnostic possibility of primary amyloidosis. PMID:27547738

  6. The SmartGeo Portal: A retrospective

    NASA Astrophysics Data System (ADS)

    Heilmann, Zeno; Satta, Guido; Bonomi, Ernesto

    2016-04-01

    The SmartGeo portal was created in a follow-up project that evolved from the geophysical data imaging services of a Grid computing portal for Geoscience, called GRIDA3. The scope of the project was to support commercial geotechnical service providers as well as academic researchers working in near-surface geoscience. Starting from the existing services, the SmartGeo portal was set up on new hardware, using the latest version of the grid portal environment EnginFrame. After a first working version was established, the services were reviewed, updated and accompanied by new services according to the feedback we received from our partners. One partner for instance experienced large difficulties in a project that aimed at delineating the aquifer for finding water pollutant substances in an industrial area of Basel. The seismic imaging service inherited from the previous portal was employing a data-driven algorithm optimized to provide, directly during data acquisition, nearly in real-time a first image of the subsurface structure. Different to this, our user needed for his data from a geologically very complex and noisy urban environment the maximum lateral resolution and noise reduction possible. For this purpose we added two cutting edge data imaging algorithms able to deliver such high precision results by simultaneously optimizing, for every single image point, all parameters of the mathematical model---a procedure which increased the computational effort by one or two magnitudes, respectively. Thus, parallel computing on grid infrastructure served for maximizing the image resolution instead for generating real-time results. This proved also very useful for the data of an academic partner, recorded for imaging the structure of a shallow sedimentary basin, where we could obtain strongly improved seismic velocity information using these new algorithms. A general user request was to implement interactive data visualization tools. To fulfill this demand we took

  7. The ADRICOSM STAR GeoPortal

    NASA Astrophysics Data System (ADS)

    Giorgetti, Alessandra; Cesarini, Claudia; Gambetta, Marco; Reseghetti, Franco; Vinci, Matteo

    2010-05-01

    From Stockholm (1972) to Rio de Janeiro (1992) and to Johannesburg (2002), environmental protection objectives are related to the principles of sustainable development. This includes the following important components: participation, information, communication, training (capacity building) and education. Better information ensure more participation from individuals, and allows citizens to take part in many different actions that can influence the policy process. Participation to political decisions need access to reliable and quality controlled information. The ADRICOSM Portal was developed in order to manage data diversity, provide access to any kind of product, provide metadata completeness and accuracy. The product, as defined in ADRICOSM, is anything that can be offered to a client and that might satisfy a want or need. This implied the implementation of services that was taking into consideration the diversity of the objects to be provided to users: observations, model outputs, maps, etc. The implementation of the portal was based on two metadata levels: 1. Directory level - consisting of broad descriptions of the contents of data sets; used to locate data sets of potential interest and 2. Data level - consisting of the actual data objects. The portal was developed as a simplified front end for the partners data management systems, giving emphasis on federated access points focused on thematic aspects. This was based on the idea that specialized customer-related access points can be better carried out by delegated teams of experts who know the needs of different customers, define the user software which is most suited to them. The data management systems provide facilities for two data tracks, one in real-time (or near-realtime) and one in delayed mode. Both tracks are based on the same data sources and transmission systems, but the data follow different routes and are processed differently depending on user requirements. The real-time data and model products

  8. Altered blood-brain barrier permeability in rats with prehepatic portal hypertension turns to normal when portal pressure is lowered

    PubMed Central

    Eizayaga, Francisco; Scorticati, Camila; Prestifilippo, Juan P; Romay, Salvador; Fernandez, Maria A; Castro, José L; Lemberg, Abraham; Perazzo, Juan C

    2006-01-01

    AIM: To study the blood-brain barrier integrity in prehepatic portal hypertensive rats induced by partial portal vein ligation, at 14 and 40 d after ligation when portal pressure is spontaneously normalized. METHODS: Adult male Wistar rats were divided into four groups: Group I: Sham14d , sham operated; Group II: PH14d , portal vein stenosis; (both groups were used 14 days after surgery); Group III: Sham40d, Sham operated and Group IV: PH40d Portal vein stenosis (Groups II and IV used 40 d after surgery). Plasma ammonia, plasma and cerebrospinal fluid protein and liver enzymes concentrations were determined. Trypan and Evans blue dyes, systemically injected, were investigated in hippocampus to study blood-brain barrier integrity. Portal pressure was periodically recorded. RESULTS: Forty days after stricture, portal pressure was normalized, plasma ammonia was moderately high, and both dyes were absent in central nervous system parenchyma. All other parameters were reestablished. When portal pressure was normalized and ammonia level was lowered, but not normal, the altered integrity of blood-brain barrier becomes reestablished. CONCLUSION: The impairment of blood-brain barrier and subsequent normalization could be a mechanism involved in hepatic encephalopathy reversibility. Hemodynamic changes and ammonia could trigger blood-brain barrier alterations and its reestablishment. PMID:16552803

  9. Spectroscopic survey of LAMOST

    NASA Astrophysics Data System (ADS)

    Zhao, Yongheng

    2015-08-01

    LAMOST is a special reflecting Schmidt telescope. LAMOST breaks through the bottleneck of the large scale spectroscopic survey observation with both large aperture (effective aperture of 3.6 - 4.9m) and wide field of view (5 degrees). It is an innovative active reflecting Schmidt configuration achieved by changing mirror surface continuously to achieve a series different reflecting Schmidt system in different moments. By using the parallel controllable fiber positioning technique, the focal surface of 1.75 meters in diameter accommodates 4000 optical fibers. Also, LAMOST has 16 spectrographs with 32 CCD cameras. LAMOST is the telescope of the highest spectrum acquiring rate.In the spectroscopic survey of LAMOST from October 2011 to June 2014, LAMOST has obtained more than 4.13 million spectra of celestial objects. There are 3.27 million spectra of stars, in which the stellar parameters of 2.16 million stars were obtained.In the five-year regular survey upto 2017, LAMOST will obtaine 5 million stellar spectra, which would make substantial contribution to the study of the stellar astrophysics and the structure of the Galaxy, such as the spheroid substructure of the Galaxy, the galactic gravitational potential and the distribution of the dark matter in the Galaxy, the extremely metal poor stars and hypervelocity stars, the 3D extinction in the Galaxy, the structure of thin and thick disks of the Galaxy, and so on.

  10. The climate4impact portal: bridging the CMIP5 data infrastructure to impact users

    NASA Astrophysics Data System (ADS)

    Plieger, Maarten; Som de Cerff, Wim; Page, Christian; Hutjes, Ronald; de Jong, Fokke; Bärring, Lars; Sjökvist, Elin

    2013-04-01

    conjunction with several external websites and systems. The climate4impact portal uses X509 based short lived credentials, generated on behalf of the user with a MyProxy service. Single Sign-on (SSO) is used to make these websites and systems work together. - Discovery: Facetted search based on e.g. variable name, model and institute using the ESG search services. A catalog browser allows for browsing through CMIP5 and other climate model data catalogues (e.g. ESSENCE, EOBS, UNIDATA). - Download: Directly from ESG nodes and other THREDDS catalogs - Visualization: Visualize any data directly using ADAGUC dynamic Web Map Services. - Transformation: Transform your data into other formats, perform basic calculations and extractions using OCG Web Processing Services The current portal is a Prototype. It is built to explore state-of-art technologies to provide improved access to climate model data. The prototype will be evaluated and is the basis for development of an operational service. The portal and services provided will be sustained and supported during the development of these operational services (2013-2016) in the second phase of the FP7 IS-ENES project, ISENES2.

  11. The climate4impact portal: bridging CMIP5 data to impact users

    NASA Astrophysics Data System (ADS)

    Som de Cerff, Wim; Plieger, Maarten; Page, Christian; Hutjes, Ronald; de Jong, Fokke; Barring, Lars; Sjökvist, Elin

    2013-04-01

    Together with seven other partners (CERFACS, CNRS-IPSL, SMHI, INHGA, CMCC, WUR, MF-CNRM), KNMI is involved in the FP7 project IS-ENES (http://is.enes.org), which supports the European climate modeling infrastructure, in the work package 'Bridging Climate Research Data and the Needs of the Impact Community'. The aim of this work package is to enhance the use of climate model data and to enhance the interaction with climate effect/impact communities. The portal is based on 17 impact use cases from 5 different European countries, and is evaluated by a user panel consisting of use case owners. As the climate impact community is very broad, the focus is mainly on the scientific impact community. This work has resulted in a prototype portal, the ENES portal interface for climate impact communities, that can be visited at www.climate4impact.eu. The portal is connected to all Earth System Grid Federation (ESGF) nodes containing global climate model data (GCM data) from the fifth phase of the Coupled Model Intercomparison Project (CMIP5) and later from the Coordinated Regional Climate Downscaling Experiment (CORDEX). This global network of all major climate model data centers offers services for data description, discovery and download. The climate4impact portal connects to these services and offers a user interface for searching, visualizing and downloading global climate model data and more. A challenging task was to describe the available model data and how it can be used. The portal tries to inform users about possible caveats when using model data. All impact use cases are described in the documentation section, using highlighted keywords pointing to detailed information in the glossary. The current portal is a Prototype. It is built to explore state-of-art technologies to provide improved access to climate model data. The prototype will be evaluated and is the basis for development of an operational service. The portal and services provided will be sustained and

  12. A Web Portal-Based Time-Aware KML Animation Tool for Exploring Spatiotemporal Dynamics of Hydrological Events

    NASA Astrophysics Data System (ADS)

    Bao, X.; Cai, X.; Liu, Y.

    2009-12-01

    Understanding spatiotemporal dynamics of hydrological events such as storms and droughts is highly valuable for decision making on disaster mitigation and recovery. Virtual Globe-based technologies such as Google Earth and Open Geospatial Consortium KML standards show great promises for collaborative exploration of such events using visual analytical approaches. However, currently there are two barriers for wider usage of such approaches. First, there lacks an easy way to use open source tools to convert legacy or existing data formats such as shapefiles, geotiff, or web services-based data sources to KML and to produce time-aware KML files. Second, an integrated web portal-based time-aware animation tool is currently not available. Thus users usually share their files in the portal but have no means to visually explore them without leaving the portal environment which the users are familiar with. We develop a web portal-based time-aware KML animation tool for viewing extreme hydrologic events. The tool is based on Google Earth JavaScript API and Java Portlet standard 2.0 JSR-286, and it is currently deployable in one of the most popular open source portal frameworks, namely Liferay. We have also developed an open source toolkit kml-soc-ncsa (http://code.google.com/p/kml-soc-ncsa/) to facilitate the conversion of multiple formats into KML and the creation of time-aware KML files. We illustrate our tool using some example cases, in which drought and storm events with both time and space dimension can be explored in this web-based KML animation portlet. The tool provides an easy-to-use web browser-based portal environment for multiple users to collaboratively share and explore their time-aware KML files as well as improving the understanding of the spatiotemporal dynamics of the hydrological events.

  13. Culture Model of Rat Portal Myofibroblasts.

    PubMed

    El Mourabit, Haquima; Loeuillard, Emilien; Lemoinne, Sara; Cadoret, Axelle; Housset, Chantal

    2016-01-01

    Myofibroblasts are matrix-producing cells with contractile properties, usually characterized by de novo expression of alpha-smooth muscle actin, that arise in fibrotic diseases. Hepatic stellate cells (HSCs), known as perisinusoidal cells containing auto-fluorescent vitamin A, are the major although not exclusive source of myofibroblasts in the injured liver. Portal myofibroblasts (PMFs) have been defined as liver myofibroblasts derived from cells that are distinct from HSCs and located in the portal tract. Here, we describe the protocol we have established to obtain rat PMFs in culture. In this method, the biliary tree is (i) separated from the liver parenchyma by in situ enzymatic perfusion of the liver, (ii) minced and further digested in vitro, until bile duct segments are isolated by sequential filtration. Bile duct isolates free of HSC contaminants, form small cell clusters, which initially comprise a large majority of epithelial cells. In culture conditions (fetal bovine serum) that provide a growth advantage to mesenchymal cells over epithelial cells, the epithelial cells die and detach from the substrate, while spindle-shaped cells outgrow from the periphery of the cell clusters, as shown by video-microscopy. These cells are highly proliferative and after 4-5 days, the culture is composed exclusively of fully differentiated myofibroblasts, which express alpha-smooth muscle actin and collagen 1, and secrete abundant collagen. We found no evidence for epithelial-mesenchymal transition, i.e., no co-expression of alpha-smooth muscle actin and cytokeratin at any stage, while cytokeratin becomes undetectable in the confluent cells. PMFs obtained by this method express the genes that were previously reported to be overexpressed in non-HSC or portal fibroblast-derived liver myofibroblasts as compared to HSC-derived myofibroblasts, including the most discriminant, collagen 15, fibulin 2, and Thy-1. After one passage, PMFs retain the same phenotypic features as in

  14. Culture Model of Rat Portal Myofibroblasts

    PubMed Central

    El Mourabit, Haquima; Loeuillard, Emilien; Lemoinne, Sara; Cadoret, Axelle; Housset, Chantal

    2016-01-01

    Myofibroblasts are matrix-producing cells with contractile properties, usually characterized by de novo expression of alpha-smooth muscle actin, that arise in fibrotic diseases. Hepatic stellate cells (HSCs), known as perisinusoidal cells containing auto-fluorescent vitamin A, are the major although not exclusive source of myofibroblasts in the injured liver. Portal myofibroblasts (PMFs) have been defined as liver myofibroblasts derived from cells that are distinct from HSCs and located in the portal tract. Here, we describe the protocol we have established to obtain rat PMFs in culture. In this method, the biliary tree is (i) separated from the liver parenchyma by in situ enzymatic perfusion of the liver, (ii) minced and further digested in vitro, until bile duct segments are isolated by sequential filtration. Bile duct isolates free of HSC contaminants, form small cell clusters, which initially comprise a large majority of epithelial cells. In culture conditions (fetal bovine serum) that provide a growth advantage to mesenchymal cells over epithelial cells, the epithelial cells die and detach from the substrate, while spindle-shaped cells outgrow from the periphery of the cell clusters, as shown by video-microscopy. These cells are highly proliferative and after 4–5 days, the culture is composed exclusively of fully differentiated myofibroblasts, which express alpha-smooth muscle actin and collagen 1, and secrete abundant collagen. We found no evidence for epithelial-mesenchymal transition, i.e., no co-expression of alpha-smooth muscle actin and cytokeratin at any stage, while cytokeratin becomes undetectable in the confluent cells. PMFs obtained by this method express the genes that were previously reported to be overexpressed in non-HSC or portal fibroblast-derived liver myofibroblasts as compared to HSC-derived myofibroblasts, including the most discriminant, collagen 15, fibulin 2, and Thy-1. After one passage, PMFs retain the same phenotypic features as in

  15. Fostering Outreach, Education and Exploration of the Moon Using the Lunar Mapping & Modeling Portal

    NASA Astrophysics Data System (ADS)

    Dodge, K.; Law, E.; Malhotra, S.; Chang, G.; Kim, R. M.; Bui, B.; Sadaqathullah, S.; Day, B. H.

    2014-12-01

    The Lunar Mapping and Modeling Portal (LMMP)[1], is a web-based Portal and a suite of interactive visualization and analysis tools for users to access mapped lunar data products (including image mosaics, digital elevation models, etc.) from past and current lunar missions (e.g., Lunar Reconnaissance Orbiter, Apollo, etc.). Originally designed as a mission planning tool for the Constellation Program, LMMP has grown into a generalized suite of tools facilitating a wide range of activities in support of lunar exploration including public outreach, education, lunar mission planning and scientific research. LMMP fosters outreach, education, and exploration of the Moon by educators, students, amateur astronomers, and the general public. These efforts are enhanced by Moon Tours, LMMP's mobile application, which makes LMMP's information accessible to people of all ages, putting opportunities for real lunar exploration in the palms of their hands. Our talk will include an overview of LMMP and a demonstration of its technologies (web portals, mobile apps), to show how it serves NASA data as commodities for use by advanced visualization facilities (e.g., planetariums) and how it contributes to improving teaching and learning, increasing scientific literacy of the general public, and enriching STEM efforts. References:[1] http://www.lmmp.nasa.gov

  16. OntoFire: an ontology-based geo-portal for wildfires

    NASA Astrophysics Data System (ADS)

    Kalabokidis, K.; Athanasis, N.; Vaitis, M.

    2011-12-01

    With the proliferation of the geospatial technologies on the Internet, the role of geo-portals (i.e. gateways to Spatial Data Infrastructures) in the area of wildfires management emerges. However, keyword-based techniques often frustrate users when looking for data of interest in geo-portal environments, while little attention has been paid to shift from the conventional keyword-based to navigation-based mechanisms. The presented OntoFire system is an ontology-based geo-portal about wildfires. Through the proposed navigation mechanisms, the relationships between the data can be discovered, which would otherwise not be possible when using conventional querying techniques alone. End users can use the browsing interface to find resources of interest by using the navigation mechanisms provided. Data providers can use the publishing interface to submit new metadata, modify metadata or removing metadata in/from the catalogue. The proposed approach can improve the discovery of valuable information that is necessary to set priorities for disaster mitigation and prevention strategies. OntoFire aspires to be a focal point of integration and management of a very large amount of information, contributing in this way to the dissemination of knowledge and to the preparedness of the operational stakeholders.

  17. An educational portal to facilitate statistical literacy for the Malaysian community

    NASA Astrophysics Data System (ADS)

    Bahardin, Nadiah; Ismail, Zaleha; Abidin, Nur Liyana Zainal

    2015-02-01

    In the last decades, a considerable number of studies investigated the teaching and learning of statistics. The implications of these studies have changed the content and structure of statistics. Hence, the applications of statistics to understand the world around us should be followed by the learning of statistical concepts so that the students are aware that statistics is an important tool to solve practical life problems. There must be some platform such as materials or articles that discuss explicitly the applications of statistics in various area that reach of students. An educational web portal by the name of Dunia Matematik has been delegated to meet this need. Apart from the sections which provide numerous articles that portray statistics in real life, the portal also provides articles on history in mathematics, popular mathematicians, online quizzes, technology in mathematics education and arts in mathematics. Based on ARCS model on motivation, the four components of the model, namely attention, relevance, confidence and satisfaction are integrated in the design of the articles and activities. A rich collection of such resources which present authentic data could supplement text book materials which heavily focus onto statistical concepts and procedures. Besides motivating learning, it is expected that the web portal has the potential to develop statistical literacy, an ability to comprehend and infer the data. The final part of the paper will describe some resources that have been developed.

  18. Enabling OpenID Authentication for VO-integrated Portals

    NASA Astrophysics Data System (ADS)

    Plante, R.; Yekkirala, V.; Baker, W.

    2012-09-01

    To support interoperating services that share proprietary data and other user-specific information, the VAO Project provides login services for browser-based portals built on the open standard, OpenID. To help portal developers take advantage of this service, we have developed a downloadable toolkit for integrating OpenID single sign-on support into any portal. This toolkit provides APIs in a few languages commonly used on the server-side as well as a command-line version for use in any language. In addition to describing how to use this toolkit, we also discuss the general VAO framework for single sign-on. While a portal may, if it wishes, support any OpenID provider, the VAO service provides a few extra features to support VO interoperability. This includes a portal's ability to retrieve (with the user's permission) an X.509 certificate representing the authenticated user so that the portal can access other restricted services on the user's behalf. Other standard features of OpenID allow portals to request other information about the user; this feature will be used in the future for sharing information about a user's group membership to enable sharing within a group of collaborating scientists.

  19. Utility of endoscopic ultrasound in patients with portal hypertension.

    PubMed

    Hammoud, Ghassan M; Ibdah, Jamal A

    2014-10-21

    Endoscopic ultrasound (EUS) has revolutionized the diagnostic and therapeutic approach to patients with gastrointestinal disorders. Its application in patients with liver disease and portal hypertension is increasing. Patients with chronic liver disease are at risk for development of portal hypertension sequale such as ascites, spontaneous bacterial peritonitis and gastroesophageal varices. Bleeding esophageal and gastric varices are among the most common causes of mortality in patients with cirrhosis. Thus, early detection and treatment improve the outcome in this population. EUS can improve the detection and diagnosis of gastroesophageal varices and collateral veins and can provide endoscopic therapy of gastroesophageal varices such as EUS-guided sclerotherapy of esophageal collateral vessels and EUS-guided cynoacrylate (Glue) injection of gastric varices. EUS can also provide knowledge on the efficacy of pharmacotherapy of portal hypertension. Furthermore, EUS can provide assessment and prediction of variceal recurrence after endoscopic therapy and assessment of portal hemodynamics such as E-Flow and Doppler study of the azygous and portal veins. Moreover, EUS-guided fine needle aspiration may provide cytologic diagnosis of focal hepatic tumors and analysis of free abdominal fluid. Using specialized EUS-guided needle biopsy, a sample of liver tissue can be obtained to diagnose and evaluate for chronic liver disease. EUS-guided fine needle injection can be used to study portal vein pressure and hemodynamics, and potentially could be used to assist in exact measurement of portal vein pressure and placement of intrahepatic portosystemic shunt. PMID:25339809

  20. Portal provides access for carbon reduction.

    PubMed

    Baillie, Jonathan

    2012-01-01

    How the lessons learned from a concerted Marks & Spencer sustainability drive that was established, and subsequently enthusiastically championed by, the retailer's then CEO and chairman, Sir Stuart Rose, could be translated to an NHS under fierce pressure to cut its own carbon footprint, was the subject of a morning keynote session at November's Healthcare Estates 2011 conference in Manchester. The session also saw the official launch of a new online portal, established jointly by BRE and the University College London Hospitals NHS Foundation Trust, which will enable NHS Trusts to share experience, and obtain valuable advice and guidance, to assist them in their efforts to be 'greener'. HEJ editor Jonathan Baillie reports. PMID:22332312

  1. Radiation portal monitor system and method

    DOEpatents

    Morris, Christopher; Borozdin, Konstantin N.; Green, J. Andrew; Hogan, Gary E.; Makela, Mark F.; Priedhorsky, William C.; Saunders, Alexander; Schultz, Larry J.; Sossong, Michael J.

    2009-12-15

    A portal monitoring system has a cosmic ray charged particle tracker with a plurality of drift cells. The drift cells, which can be for example aluminum drift tubes, can be arranged at least above and below a volume to be scanned to thereby track incoming and outgoing charged particles, such as cosmic ray muons, whilst also detecting gamma rays. The system can selectively detect devices or materials, such as iron, lead, gold and/or tungsten, occupying the volume from multiple scattering of the charged particles passing through the volume and can also detect any radioactive sources occupying the volume from gamma rays emitted therefrom. If necessary, the drift tubes can be sealed to eliminate the need for a gas handling system. The system can be employed to inspect occupied vehicles at border crossings for nuclear threat objects.

  2. Portal hypertension in kala-azar

    PubMed Central

    Datta, D. V.; Saha, S.; Grover, S. L.; Singh, Samant A.; Chakravarti, R. N.; Chhuttani, P. N.

    1972-01-01

    The present study records haemodynamic studies in three patients with kala-azar, a parasitic disease. All the three patients had high intrasplenic pressure, mild to moderate elevation of wedged hepatic vein pressure, and increased or normal estimated hepatic blood flow. Liver histology showed marked proliferation and swelling of Kupffer cells in the sinusoids. One patient was studied serially for nine months following treatment which showed persistent elevation of intrasplenic pressure though wedge pressure and liver blood flow touched normal levels. Liver biopsy was essentially normal at this stage. These findings may have some relevance to the role of different parasitic infections in the pathogenesis of a heterogeneous group of non-cirrhotic portal fibroses. ImagesFig. 1Fig. 2Fig. 3Fig. 4Fig. 6 PMID:5045707

  3. Vibration of x-braced portal frames

    NASA Astrophysics Data System (ADS)

    Chang, C. H.; Wang, P. Y.; Lin, Y. W.

    1987-09-01

    Both free and forced vibrations of elastic X-braced portal frames are investigated. Solutions of the Euler-Bernoulli equation for the transverse vibration coupled with the axial vibration are used. The first five natural frequencies, with the angle of inclination, α, of the bracing bars ranging from 15° to 75°, with different slenderness ratios, R, of the columns, and different stiffness of the floor beam and crossing bars, are presented along with two sets of the natural modes of the frames with α = 45°. For the forced vibration, the dynamic responses of the frames with a concentrated horizontal time dependent force acting at a top joint are studied. The responses of the frames with α = 45° are analyzed in detail.

  4. Combined portal vein resection for hilar cholangiocarcinoma

    PubMed Central

    Bai, Tao; Chen, Jie; Xie, Zhi-Bo; Ma, Liang; Liu, Jun-Jie; Zhu, Shao-Liang; Wu, Fei-Xiang; Li, Le-Qun

    2015-01-01

    Background: Surgery is the only curative therapy for patients with hilar cholangiocarcinoma (HCCA). Combined portal vein resection (PVR) could achieve negative resection margins in HCCA patients with portal vein invasion. This systematic review aimed to analysis the efficiency of combined PVR for HCCA. Methods: MEDLINE, EMBASE, the Cochrane Library, the Chinese National Knowledge Infrastructure database, and clinical trial registries were searched through April 2015. Risk ratios (RRs), and 95% confidence intervals (CIs) were calculated. Results: The analysis included 21 retrospective studies, altogether involving 2403 patients (patients with PVR, n=637; patients without PVR, n=1766). Patients with PVR were likely to have more advanced HCCA (lymphatic invasion: RR=1.14, 95% CI 1.02 to 1.28; perineural invasion: RR=1.31, 95% CI 1.05 to 1.63) and suffered less curative resections (RR=0.89, 95% CI 0.75 to 0.99). Postoperative morbidity was similar between patients with or without PVR (RR=1.06, 95% CI 0.94 to 1.02). Patients with PVR suffered higher mortality rate (RR=1.52, 95% CI 1.06 to 2.18), and worse 5-year survival rate (RR=0.67, 95% CI 0.49 to 0.91). Conclusion: Combined PVR for HCCA patients would not increase postoperative morbidity rate. However, ascribed to PVR group concluded more advanced HCCA patients; patients with PVR had increased postoperative mortality rate and worse survival rate. The results still need further high quality trails for validation. PMID:26885035

  5. Development of Geospatial Map Based Election Portal

    NASA Astrophysics Data System (ADS)

    Gupta, A. Kumar Chandra; Kumar, P.; Vasanth Kumar, N.

    2014-11-01

    The Geospatial Delhi Limited (GSDL), a Govt. of NCT of Delhi Company formed in order to provide the geospatial information of National Capital Territory of Delhi (NCTD) to the Government of National Capital Territory of Delhi (GNCTD) and its organs such as DDA, MCD, DJB, State Election Department, DMRC etc., for the benefit of all citizens of Government of National Capital Territory of Delhi (GNCTD). This paper describes the development of Geospatial Map based Election portal (GMEP) of NCT of Delhi. The portal has been developed as a map based spatial decision support system (SDSS) for pertain to planning and management of Department of Chief Electoral Officer, and as an election related information searching tools (Polling Station, Assembly and parliamentary constituency etc.,) for the citizens of NCTD. The GMEP is based on Client-Server architecture model. It has been developed using ArcGIS Server 10.0 with J2EE front-end on Microsoft Windows environment. The GMEP is scalable to enterprise SDSS with enterprise Geo Database & Virtual Private Network (VPN) connectivity. Spatial data to GMEP includes delimited precinct area boundaries of Voters Area of Polling stations, Assembly Constituency, Parliamentary Constituency, Election District, Landmark locations of Polling Stations & basic amenities (Police Stations, Hospitals, Schools and Fire Stations etc.). GMEP could help achieve not only the desired transparency and easiness in planning process but also facilitates through efficient & effective tools for management of elections. It enables a faster response to the changing ground realities in the development planning, owing to its in-built scientific approach and open-ended design.

  6. Portal annular pancreas: the pancreatic duct ring sign on MRCP.

    PubMed

    Lath, Chinar O; Agrawal, Dilpesh S; Timins, Michael E; Wein, Melissa M

    2015-12-01

    Portal annular pancreas is a rare pancreatic variant in which the uncinate process of the pancreas extends and fuses to the dorsal surface of the body of the pancreas by surrounding the portal vein. It is asymptomatic, but it can be mistaken for a pancreatic head mass on imaging and could also have serious consequences during pancreatic surgery, if unrecognized. We report this case of a 53-year-old female patient who was diagnosed to have portal annular pancreas on the basis of an unusual course (ring appearance) of the main pancreatic duct on magnetic resonance cholangiopancreatography, not described earlier in the radiology literature. PMID:26649117

  7. 3. East portal of Tunnel 27, view to northeast from ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. East portal of Tunnel 27, view to northeast from atop cut bank, 210mm lens. This view shows to good effect the original construction of the Harriman period tunnels, which were concreted fifty feet in from the portals with the balance being timber lined. In 1965 the east end of the tunnel collapsed, with the result that approximately 115 feet of the east end was 'daylighted' and the original east portal and concreted end were left in place, free-standing as seen here. - Central Pacific Transcontinental Railroad, Tunnel No. 27, Milepost 133.9, Applegate, Placer County, CA

  8. Portal dosimetry for VMAT using integrated images obtained during treatment

    SciTech Connect

    Bedford, James L. Hanson, Ian M.; Hansen, Vibeke Nordmark

    2014-02-15

    Purpose: Portal dosimetry provides an accurate and convenient means of verifying dose delivered to the patient. A simple method for carrying out portal dosimetry for volumetric modulated arc therapy (VMAT) is described, together with phantom measurements demonstrating the validity of the approach. Methods: Portal images were predicted by projecting dose in the isocentric plane through to the portal image plane, with exponential attenuation and convolution with a double-Gaussian scatter function. Appropriate parameters for the projection were selected by fitting the calculation model to portal images measured on an iViewGT portal imager (Elekta AB, Stockholm, Sweden) for a variety of phantom thicknesses and field sizes. This model was then used to predict the portal image resulting from each control point of a VMAT arc. Finally, all these control point images were summed to predict the overall integrated portal image for the whole arc. The calculated and measured integrated portal images were compared for three lung and three esophagus plans delivered to a thorax phantom, and three prostate plans delivered to a homogeneous phantom, using a gamma index for 3% and 3 mm. A 0.6 cm{sup 3} ionization chamber was used to verify the planned isocentric dose. The sensitivity of this method to errors in monitor units, field shaping, gantry angle, and phantom position was also evaluated by means of computer simulations. Results: The calculation model for portal dose prediction was able to accurately compute the portal images due to simple square fields delivered to solid water phantoms. The integrated images of VMAT treatments delivered to phantoms were also correctly predicted by the method. The proportion of the images with a gamma index of less than unity was 93.7% ± 3.0% (1SD) and the difference between isocenter dose calculated by the planning system and measured by the ionization chamber was 0.8% ± 1.0%. The method was highly sensitive to errors in monitor units and

  9. Portal annular pancreas: the pancreatic duct ring sign on MRCP

    PubMed Central

    Lath, Chinar O.; Agrawal, Dilpesh S.; Timins, Michael E.; Wein, Melissa M.

    2015-01-01

    Portal annular pancreas is a rare pancreatic variant in which the uncinate process of the pancreas extends and fuses to the dorsal surface of the body of the pancreas by surrounding the portal vein. It is asymptomatic, but it can be mistaken for a pancreatic head mass on imaging and could also have serious consequences during pancreatic surgery, if unrecognized. We report this case of a 53-year-old female patient who was diagnosed to have portal annular pancreas on the basis of an unusual course (ring appearance) of the main pancreatic duct on magnetic resonance cholangiopancreatography, not described earlier in the radiology literature. PMID:26649117

  10. The Modified Mid-Anterior Portal for Hip Arthroscopy

    PubMed Central

    Matsuda, Dean K.; Villamor, Angel

    2014-01-01

    The modified mid-anterior portal is a utilitarian hip arthroscopy working portal that permits dual-portal comprehensive surgery for femoroacetabular impingement and related chondrolabral procedures without the need for interportal exchange. Its distal location facilitates labral reparative and reconstructive procedures while minimizing iatrogenic acetabular chondral damage. The relatively lateral location permits instrument navigation not only along the anterosuperior acetabular rim and anterolateral proximal femur typically required for acetabuloplasty and femoroplasty but even to the posterior regions of the hip in cases of global pincer femoroacetabular impingement and posterior extensions of cam morphology and the anteromedial proximal femur while avoiding direct injury to the lateral femoral cutaneous nerve. PMID:25276606

  11. Technology.

    ERIC Educational Resources Information Center

    Online-Offline, 1998

    1998-01-01

    Focuses on technology, on advances in such areas as aeronautics, electronics, physics, the space sciences, as well as computers and the attendant progress in medicine, robotics, and artificial intelligence. Describes educational resources for elementary and middle school students, including Web sites, CD-ROMs and software, videotapes, books,…

  12. Spectroscopic ellipsometer for ultra thin film

    NASA Astrophysics Data System (ADS)

    Akashika, Kumiko; Shiota, Shuji; Yamaguchi, Shinji; Horie, Masahiro; Kobayashi, Masayoshi

    2008-03-01

    As semiconductor technology has advanced, the films have become thinner and changed to multi-layer films, such as gate dielectric construction. To deal with these trends, we are continuing development of our spectroscopic ellipsometer with elliptical polarization. We chose a Rotating-Analyzer Ellipsometer (RAE) configuration. The incident light in this type of device is usually polarized linearly, because polarizers do not disperse the light. But the incident light in the ellipsometer described in this paper is elliptical, which has a nearly circular polarization. In this paper, we introduce a technique for solving the dispersion problem.

  13. Extending the Lunar Mapping and Modeling Portal - New Capabilities and New Worlds

    NASA Astrophysics Data System (ADS)

    Day, Brian; Law, Emily

    2015-11-01

    NASA’s Lunar Mapping and Modeling Portal (LMMP) provides a web-based Portal and a suite of interactive visualization and analysis tools to enable mission planners, lunar scientists, and engineers to access mapped lunar data products from past and current lunar missions (http://lmmp.nasa.gov). During the past year, the capabilities and data served by LMMP have been significantly expanded. New interfaces are providing improved ways to access and visualize data. Many of the recent enhancements to LMMP have been specifically in response to the requirements of NASA's proposed Resource Prospector lunar rover, and as such, provide an excellent example of the application of LMMP to mission planning.At the request of NASA’s Science Mission Directorate, LMMP’s technology and capabilities are now being extended to additional planetary bodies. New portals for Vesta and Mars are the first of these new products to be released.On March 31, 2015, the LMMP team released Vesta Trek (http://vestatrek.jpl.nasa.gov), a web-based application applying LMMP technology to visualize the asteroid Vesta. Data gathered from multiple instruments aboard Dawn have been compiled into Vesta Trek’s user-friendly set of tools, enabling users to study the asteroid’s features.Released on July 1, 2015, Mars Trek replicates the functionality of Vesta Trek for the surface of Mars. While the entire surface of Mars is covered, higher levels of resolution and greater numbers of data products are provided for special areas of interest. Early releases focus on past, current, and future robotic sites of operation. Future releases will add many new data products and analysis tools as Mars Trek has been selected for use in site selection for the Mars 2020 rover and in identifying potential human landing sites on Mars.Other destinations will follow soon. The Solar Sytem Exploration Research Virtual Institute, which manages the project, invites the user community to provide suggestions and requests as the

  14. Open source clinical portals: a model for healthcare information systems to support care processes and feed clinical research. An Italian case of design, development, reuse, and exploitation.

    PubMed

    Locatelli, Paolo; Baj, Emanuele; Restifo, Nicola; Origgi, Gianni; Bragagia, Silvia

    2011-01-01

    Open source is a still unexploited chance for healthcare organizations and technology providers to answer to a growing demand for innovation and to join economical benefits with a new way of managing hospital information systems. This chapter will present the case of the web enterprise clinical portal developed in Italy by Niguarda Hospital in Milan with the support of Fondazione Politecnico di Milano, to enable a paperless environment for clinical and administrative activities in the ward. This represents also one rare case of open source technology and reuse in the healthcare sector, as the system's porting is now taking place at Besta Neurological Institute in Milan. This institute is customizing the portal to feed researchers with structured clinical data collected in its portal's patient records, so that they can be analyzed, e.g., through business intelligence tools. Both organizational and clinical advantages are investigated, from process monitoring, to semantic data structuring, to recognition of common patterns in care processes. PMID:21431608

  15. Characterization of a prototype neutron portal monitor detector

    NASA Astrophysics Data System (ADS)

    Nakhoul, Nabil

    The main objective of this thesis is to provide characterization measurements on a prototype neutron portal monitor (NPM) detector constructed at the University of Massachusetts Lowell. NPM detectors are deployed at all United States border crossings and shipping ports to stop the illicit transfer of weapons-grade plutonium (WGPu) into our country. This large prototype detector with its 0.93 square meter face area is based on thermal neutron capture in 6Li as an alternate technology to the current, very expensive, 3He-based NPM. A neutron detection efficiency of 27.5 % is measured with a 252Cf source which has a spontaneous fission neutron spectrum very similar to that of 240Pu in WGPu. Measurements with an intense 137Cs source establish the extreme insensitivity of the prototype NPM to gamma-ray backgrounds with only one additional count registered for 1.1 million incident gamma rays. This detector also has the ability to locate neutron sources to within an angle of a few degrees. Its sensitivity is further demonstrated by discovering in a few-second measurement the presence of a 2 curie PuBe neutron source even at a distance of 95.5 feet. This thesis also covers in considerable detail the design features that give rise to both a high intrinsic neutron detection efficiency and an extreme gamma-ray insensitivity.

  16. Talkoot Portals: Discover, Tag, Share, and Reuse Collaborative Science Workflows

    NASA Astrophysics Data System (ADS)

    Wilson, B. D.; Ramachandran, R.; Lynnes, C.

    2009-05-01

    A small but growing number of scientists are beginning to harness Web 2.0 technologies, such as wikis, blogs, and social tagging, as a transformative way of doing science. These technologies provide researchers easy mechanisms to critique, suggest and share ideas, data and algorithms. At the same time, large suites of algorithms for science analysis are being made available as remotely-invokable Web Services, which can be chained together to create analysis workflows. This provides the research community an unprecedented opportunity to collaborate by sharing their workflows with one another, reproducing and analyzing research results, and leveraging colleagues' expertise to expedite the process of scientific discovery. However, wikis and similar technologies are limited to text, static images and hyperlinks, providing little support for collaborative data analysis. A team of information technology and Earth science researchers from multiple institutions have come together to improve community collaboration in science analysis by developing a customizable "software appliance" to build collaborative portals for Earth Science services and analysis workflows. The critical requirement is that researchers (not just information technologists) be able to build collaborative sites around service workflows within a few hours. We envision online communities coming together, much like Finnish "talkoot" (a barn raising), to build a shared research space. Talkoot extends a freely available, open source content management framework with a series of modules specific to Earth Science for registering, creating, managing, discovering, tagging and sharing Earth Science web services and workflows for science data processing, analysis and visualization. Users will be able to author a "science story" in shareable web notebooks, including plots or animations, backed up by an executable workflow that directly reproduces the science analysis. New services and workflows of interest will be

  17. PoPLAR: Portal for Petascale Lifescience Applications and Research

    PubMed Central

    2013-01-01

    Background We are focusing specifically on fast data analysis and retrieval in bioinformatics that will have a direct impact on the quality of human health and the environment. The exponential growth of data generated in biology research, from small atoms to big ecosystems, necessitates an increasingly large computational component to perform analyses. Novel DNA sequencing technologies and complementary high-throughput approaches--such as proteomics, genomics, metabolomics, and meta-genomics--drive data-intensive bioinformatics. While individual research centers or universities could once provide for these applications, this is no longer the case. Today, only specialized national centers can deliver the level of computing resources required to meet the challenges posed by rapid data growth and the resulting computational demand. Consequently, we are developing massively parallel applications to analyze the growing flood of biological data and contribute to the rapid discovery of novel knowledge. Methods The efforts of previous National Science Foundation (NSF) projects provided for the generation of parallel modules for widely used bioinformatics applications on the Kraken supercomputer. We have profiled and optimized the code of some of the scientific community's most widely used desktop and small-cluster-based applications, including BLAST from the National Center for Biotechnology Information (NCBI), HMMER, and MUSCLE; scaled them to tens of thousands of cores on high-performance computing (HPC) architectures; made them robust and portable to next-generation architectures; and incorporated these parallel applications in science gateways with a web-based portal. Results This paper will discuss the various developmental stages, challenges, and solutions involved in taking bioinformatics applications from the desktop to petascale with a front-end portal for very-large-scale data analysis in the life sciences. Conclusions This research will help to bridge the gap

  18. Coupled Deterministic-Monte Carlo Transport for Radiation Portal Modeling

    SciTech Connect

    Smith, Leon E.; Miller, Erin A.; Wittman, Richard S.; Shaver, Mark W.

    2008-01-14

    Radiation portal monitors are being deployed, both domestically and internationally, to detect illicit movement of radiological materials concealed in cargo. Evaluation of the current and next generations of these radiation portal monitor (RPM) technologies is an ongoing process. 'Injection studies' that superimpose, computationally, the signature from threat materials onto empirical vehicle profiles collected at ports of entry, are often a component of the RPM evaluation process. However, measurement of realistic threat devices can be both expensive and time-consuming. Radiation transport methods that can predict the response of radiation detection sensors with high fidelity, and do so rapidly enough to allow the modeling of many different threat-source configurations, are a cornerstone of reliable evaluation results. Monte Carlo methods have been the primary tool of the detection community for these kinds of calculations, in no small part because they are particularly effective for calculating pulse-height spectra in gamma-ray spectrometers. However, computational times for problems with a high degree of scattering and absorption can be extremely long. Deterministic codes that discretize the transport in space, angle, and energy offer potential advantages in computational efficiency for these same kinds of problems, but the pulse-height calculations needed to predict gamma-ray spectrometer response are not readily accessible. These complementary strengths for radiation detection scenarios suggest that coupling Monte Carlo and deterministic methods could be beneficial in terms of computational efficiency. Pacific Northwest National Laboratory and its collaborators are developing a RAdiation Detection Scenario Analysis Toolbox (RADSAT) founded on this coupling approach. The deterministic core of RADSAT is Attila, a three-dimensional, tetrahedral-mesh code originally developed by Los Alamos National Laboratory, and since expanded and refined by Transpire, Inc. [1

  19. Portal vein occlusion after biliary metal stent placement in hilar cholangiocarcinoma.

    PubMed

    Woo, Kyung Hee; Kim, Jin Bae; Chang, Yoon Jung; Kim, Hyo Jung; Baek, Il Hyun; Ko, Jin Seok; Woo, Ji Young; Kim, Hong Dae; Lee, Myung Seok

    2008-06-01

    Acute symptomatic portal vein obstruction related to biliary stenting is an extremely rare but life-threatening complication. This usually occurs in patients with either tumor invasion into the portal vein or pre-existing portal vein thrombus. Therefore, the portal vein should be carefully evaluated before placing a biliary metallic stent in such patients. We describe a case of acute portal vein obstruction after placing metallic biliary stents in a patient with a periductal-infiltrating type of hilar cholangiocarcinoma. PMID:20485610

  20. High-pressure xenon detector development at Constellation Technology Corporation

    NASA Astrophysics Data System (ADS)

    Austin, Robert A.

    2007-08-01

    Xenon-filled ionization detectors, due to their high atomic number fill gas ( Z=54), moderate densities (˜0.3-0.5 g/cm 3) and good energy resolution (2-4% at 662 keV), fill an important niche between more familiar technologies such as NaI(Tl) scintillators and germanium detectors. Until recently, difficulties with obtaining sufficient xenon purity, reducing microphonic sensitivity, and developing low-noise electronics compatible with small ionization signals have hampered the development of this nuclear detection field. Constellation Technology Corporation, whose experience with xenon detectors goes back to the mid 1990s, has made significant progress in these areas and has developed a commercial line of detectors with active volumes ranging from small (35 g Xe) to large (1400 g Xe). Current applications for Constellation's detectors are principally in the area of defense (Unmanned Aerial Vehicles and Advanced Spectroscopic Portals), but as awareness of this technology grows, it will surely find applications in a much expanded range of fields.

  1. Demonstrating the climate4impact portal: bridging the CMIP5 data infrastructure to impact users

    NASA Astrophysics Data System (ADS)

    Plieger, Maarten; Som de Cerff, Wim; Page, Christian; Hutjes, Ronald; de Jong, Fokke; Bärring, Lars; Sjökvist, Elin

    2013-04-01

    using the ESG search services. A catalog browser allows for browsing through CMIP5 and other climate model data catalogues (e.g. ESSENCE, EOBS, UNIDATA). - Download: Directly from ESG nodes and other THREDDS catalogs - Visualization: Visualize any data directly using ADAGUC dynamic Web Map Services. - Transformation: Transform your data into other formats, perform basic calculations and extractions using OCG Web Processing Services The current portal is a Prototype. It is built to explore state-of-art technologies to provide improved access to climate model data. The prototype will be evaluated and is the basis for development of an operational service. The portal and services provided will be sustained and supported during the development of these operational services (2013-2016) in the second phase of the FP7 IS-ENES project, ISENES2.

  2. 2. PORTAL VIEW OF BRIDGE FROM NORTH SIDE OF SANITARY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. PORTAL VIEW OF BRIDGE FROM NORTH SIDE OF SANITARY AND SHIP CANAL, LOOKING SOUTHEAST. - Chicago, Madison & Northern Railroad, Sanitary & Ship Canal Bridge, Spanning Sanitary & Ship Canal, east of Kedzie Avenue, Chicago, Cook County, IL

  3. 4. West portal of Tunnel 5, view to the northwest ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. West portal of Tunnel 5, view to the northwest from within the mudshed, 135mm lens with electronic flash fill. - Southern Pacific Railroad Natron Cutoff, Tunnel 5, Milepost 545.2, McCredie Springs, Lane County, OR

  4. 2. CONFLUENCE POOL, DETAIL OF TUNNEL PORTAL WITH WATER ENTERING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. CONFLUENCE POOL, DETAIL OF TUNNEL PORTAL WITH WATER ENTERING FROM SANTA ANA RIVER. VIEW TO NORTHEAST. - Santa Ana River Hydroelectric System, Bear Creek Diversion Dam & Confluence Pool, Redlands, San Bernardino County, CA

  5. 5. East portal of Tunnel 5, contextual view to the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. East portal of Tunnel 5, contextual view to the northeast from the west end of Cruzette Siding, 210mm lens. - Southern Pacific Railroad Natron Cutoff, Tunnel 5, Milepost 545.2, McCredie Springs, Lane County, OR

  6. Patient portals - An online tool for your health

    MedlinePlus

    ... gov/ency/patientinstructions/000880.htm Patient portals - An online tool for your health To use the sharing ... a website for your personal health care. The online tool helps you to keep track of your ...

  7. 4. APPROACH OF CARRS MILL ROAD TO THE SOUTH PORTAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. APPROACH OF CARRS MILL ROAD TO THE SOUTH PORTAL OF THE MITCHELLS MILL BRIDGE; VIEW TO NORTH. - Mitchell's Mill Bridge, Spanning Winter's Run on Carrs Mill Road, west of Bel Air, Bel Air, Harford County, MD

  8. 7. NORTH WEB AND WEST PORTAL. VIEW TO SOUTHEAST FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. NORTH WEB AND WEST PORTAL. VIEW TO SOUTHEAST FROM BLAIR RAILROAD BRIDGE. - Abraham Lincoln Memorial Bridge, Spanning Missouri River on Highway 30 between Nebraska & Iowa, Blair, Washington County, NE

  9. 15. SOUTH WEB AND WEST PORTAL OF MIDDLE THROUGH TRUSS. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. SOUTH WEB AND WEST PORTAL OF MIDDLE THROUGH TRUSS. VIEW TO NORTHEAST. - Abraham Lincoln Memorial Bridge, Spanning Missouri River on Highway 30 between Nebraska & Iowa, Blair, Washington County, NE

  10. Cut at eastern approach, with portal obscured by train entering ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Cut at eastern approach, with portal obscured by train entering tunnel, looking NNW. - Philadelphia & Reading Railroad, Black Rock Tunnel, Beneath Black Rock Hill, southwest of Black Rock Dam, Phoenixville, Chester County, PA

  11. East portal of Tunnel No. 1292, Indigo Tunnel, showing interior ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    East portal of Tunnel No. 1292, Indigo Tunnel, showing interior timber framing, looking southwest. - Western Maryland Railway, Cumberland Extension, Pearre to North Branch, from WM milepost 125 to 160, Pearre, Washington County, MD

  12. West portal of Tunnel No. 1292, Indigo Tunnel at milepost ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    West portal of Tunnel No. 1292, Indigo Tunnel at milepost 129.95, largely obscured by overgrowth. - Western Maryland Railway, Cumberland Extension, Pearre to North Branch, from WM milepost 125 to 160, Pearre, Washington County, MD

  13. 6. OBLIQUE VIEW, FROM SOUTHWEST, SHOWING WEST PORTAL, THROUGH TRUSSES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. OBLIQUE VIEW, FROM SOUTHWEST, SHOWING WEST PORTAL, THROUGH TRUSSES OF WEST SPAN, AND PORTION OF WEST APPROACH - Glendale Road Bridge, Spanning Deep Creek Lake on Glendale Road, McHenry, Garrett County, MD

  14. 1. West portal of Tunnel 17, contextual view to northeast, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. West portal of Tunnel 17, contextual view to northeast, 135mm lens. The tunnel penetrates the toe of Dorris Hill, which rises to the left. - Southern Pacific Railroad Natron Cutoff, Tunnel No. 17, Milepost 408, Dorris, Siskiyou County, CA

  15. The Portals 4.0 network programming interface.

    SciTech Connect

    Barrett, Brian W.; Brightwell, Ronald Brian; Pedretti, Kevin Thomas Tauke; Wheeler, Kyle Bruce; Hemmert, Karl Scott; Riesen, Rolf E.; Underwood, Keith Douglas; Maccabe, Arthur Bernard; Hudson, Trammell B.

    2012-11-01

    This report presents a specification for the Portals 4.0 network programming interface. Portals 4.0 is intended to allow scalable, high-performance network communication between nodes of a parallel computing system. Portals 4.0 is well suited to massively parallel processing and embedded systems. Portals 4.0 represents an adaption of the data movement layer developed for massively parallel processing platforms, such as the 4500-node Intel TeraFLOPS machine. Sandia's Cplant cluster project motivated the development of Version 3.0, which was later extended to Version 3.3 as part of the Cray Red Storm machine and XT line. Version 4.0 is targeted to the next generation of machines employing advanced network interface architectures that support enhanced offload capabilities.

  16. General view of north portals showing three abandoned roadbeds. View ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of north portals showing three abandoned roadbeds. View south - New York, New Haven & Hartford Railroad, Fort Point Channel Rolling Lift Bridge, Spanning Fort Point Channel, Boston, Suffolk County, MA

  17. Coastal and Marine Geology Program video and photograph portal

    USGS Publications Warehouse

    Golden, Nadine E.; Ackerman, Seth D.

    2015-01-01

    Search all Coastal and Marine Geology Program imagery by selecting "Explore Data Layers." Or select Pacific, Atlantic, or Gulf Coast to enter the portal by region. Or start with the tutorial then dive in!

  18. 1. NORTH HAMMA HAMMA BRIDGE LOOKING SOUTH THROUGH PORTALS OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. NORTH HAMMA HAMMA BRIDGE LOOKING SOUTH THROUGH PORTALS OF BOTH THE NORTH AND SOUTH BRIDGES - North Hamma Hamma River Bridge, Spanning Hamma Hamma River Bridge at U.S. Route 101, Eldon, Mason County, WA

  19. Grid infrastructure to support science portals for large scale instruments.

    SciTech Connect

    von Laszewski, G.; Foster, I.

    1999-09-29

    Soon, a new generation of scientific workbenches will be developed as a collaborative effort among various research institutions in the US. These scientific workbenches will be accessed in the Web via portals. Reusable components are needed to build such portals for different scientific disciplines, allowing uniform desktop access to remote resources. Such components will include tools and services enabling easy collaboration, job submission, job monitoring, component discovery, and persistent object storage. Based on experience gained from Grand Challenge applications for large-scale instruments, we demonstrate how Grid infrastructure components can be used to support the implementation of science portals. The availability of these components will simplify the prototype implementation of a common portal architecture.

  20. Fetal liver hematopoietic stem cell niches associate with portal vessels

    PubMed Central

    Khan, Jalal A.; Mendelson, Avital; Kunisaki, Yuya; Birbrair, Alexander; Kou, Yan; Arnal-Estapé, Anna; Pinho, Sandra; Ciero, Paul; Nakahara, Fumio; Ma’ayan, Avi; Bergman, Aviv; Merad, Miriam; Frenette, Paul S.

    2015-01-01

    Whereas the cellular basis of the hematopoietic stem cell (HSC) niche in the bone marrow has been characterized, the nature of the fetal liver (FL) niche is not yet elucidated. We show that Nestin+NG2+ pericytes associate with portal vessels, forming a niche promoting HSC expansion. Nestin+NG2+ cells and HSCs scale during development with the fractal branching patterns of portal vessels, tributaries of the umbilical vein. After closure of the umbilical inlet at birth, portal vessels undergo a transition from Neuropilin-1+Ephrin-B2+ artery to EphB4+ vein phenotype, associated with a loss of periportal Nestin+NG2+ cells and emigration of HSCs away from portal vessels. These data support a model in which HSCs are titrated against a periportal vascular niche with a fractal-like organization enabled by placental circulation. PMID:26634440

  1. SHENANDOAHDIVES (MAYFLOWER) MINE PORTAL SITE, LOOKING WEST. NOTE FOUNDATION AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    SHENANDOAH-DIVES (MAYFLOWER) MINE PORTAL SITE, LOOKING WEST. NOTE FOUNDATION AT RIGHT AND RADIATOR AT LOWER LEFT, BOTH REMNANTS OF THE DORMITORY. - Shenandoah-Dives Mill, 135 County Road 2, Silverton, San Juan County, CO

  2. A portal for the ocean biogeographic information system

    USGS Publications Warehouse

    Zhang, Yunqing; Grassle, J. F.

    2002-01-01

    Since its inception in 1999 the Ocean Biogeographic Information System (OBIS) has developed into an international science program as well as a globally distributed network of biogeographic databases. An OBIS portal at Rutgers University provides the links and functional interoperability among member database systems. Protocols and standards have been established to support effective communication between the portal and these functional units. The portal provides distributed data searching, a taxonomy name service, a GIS with access to relevant environmental data, biological modeling, and education modules for mariners, students, environmental managers, and scientists. The portal will integrate Census of Marine Life field projects, national data archives, and other functional modules, and provides for network-wide analyses and modeling tools.

  3. The portals 4.0.1 network programming interface.

    SciTech Connect

    Barrett, Brian W.; Brightwell, Ronald Brian; Pedretti, Kevin Thomas Tauke; Wheeler, Kyle Bruce; Hemmert, Karl Scott; Riesen, Rolf E.; Underwood, Keith Douglas; Maccabe, Arthur Bernard; Hudson, Trammell B.

    2013-04-01

    This report presents a specification for the Portals 4.0 network programming interface. Portals 4.0 is intended to allow scalable, high-performance network communication between nodes of a parallel computing system. Portals 4.0 is well suited to massively parallel processing and embedded systems. Portals 4.0 represents an adaption of the data movement layer developed for massively parallel processing platforms, such as the 4500-node Intel TeraFLOPS machine. Sandia's Cplant cluster project motivated the development of Version 3.0, which was later extended to Version 3.3 as part of the Cray Red Storm machine and XT line. Version 4.0 is targeted to the next generation of machines employing advanced network interface architectures that support enhanced offload capabilities. 3

  4. The Astrophysics Simulation Collaboratory portal: A framework foreffective distributed research

    SciTech Connect

    Bondarescu, Ruxandra; Allen, Gabrielle; Daues, Gregory; Kelly,Ian; Russell, Michael; Seidel, Edward; Shalf, John; Tobias, Malcolm

    2003-03-03

    We describe the motivation, architecture, and implementation of the Astrophysics Simulation Collaboratory (ASC) portal. The ASC project provides a web-based problem solving framework for the astrophysics community that harnesses the capabilities of emerging computational grids.

  5. Detail of track girder, south portal and granite piers at ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of track girder, south portal and granite piers at low tide. View Northwest - New York, New Haven & Hartford Railroad, Fort Point Channel Rolling Lift Bridge, Spanning Fort Point Channel, Boston, Suffolk County, MA

  6. VIEW OF BRIDGE CANTILEVER THROUGH TRUSS CANTILEVER PORTAL ON WEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF BRIDGE CANTILEVER THROUGH TRUSS CANTILEVER PORTAL ON WEST BANK SIDE LOOKING NORTHWEST. - Huey P. Long Bridge, Spanning Mississippi River approximately midway between nine & twelve mile points upstream from & west of New Orleans, Jefferson, Jefferson Parish, LA

  7. Oblique perspective of portal, due north. Bridge has gable roof ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Oblique perspective of portal, due north. Bridge has gable roof clad with wood shingles and has board and batten siding. - Watson Mill Bridge, Spanning South Fork Broad River, Watson Mill Road, Watson Mill Bridge State Park, Comer, Madison County, GA

  8. 4. From Skew Span to portal on span 1 looking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. From Skew Span to portal on span 1 looking up grade toward the south end. - Monongahela Connecting Railroad Company, Hot Metal Bridge, Spanning Monongahela River at mile post 3.1, Pittsburgh, Allegheny County, PA

  9. 5. From Span 6 to portal on span 5 looking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. From Span 6 to portal on span 5 looking down grade toward north end. - Monongahela Connecting Railroad Company, Hot Metal Bridge, Spanning Monongahela River at mile post 3.1, Pittsburgh, Allegheny County, PA

  10. 10. View of end portals, top chords, diagonals, verticals and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. View of end portals, top chords, diagonals, verticals and strut connections. Looking from east span to east end of west span. - Boomershine Bridge, Spanning Twin Creek, Farmersville, Montgomery County, OH

  11. 5. SOUTHWEST PORTAL AND SOUTHWEST WEB OT THROUGH TRUSSES, SHOWING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. SOUTHWEST PORTAL AND SOUTHWEST WEB OT THROUGH TRUSSES, SHOWING TOP CHORD DETAILS; VIEW TO NORTHEAST - Nebraska City Bridge, Spanning Missouri River near Highway 2 between Nebraska & Iowa, Nebraska City, Otoe County, NE

  12. 1. West portal of Tunnel 22, contextual view to the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. West portal of Tunnel 22, contextual view to the northwest, 135mm lens. Tunnel 22 pierces a ridge separating Oakridge from Westfir. - Southern Pacific Railroad Natron Cutoff, Tunnel 22, Milepost 581.85, Oakridge, Lane County, OR

  13. Elevation view of west portal, looking due east. Eastbound train ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Elevation view of west portal, looking due east. Eastbound train entering tunnel. Allegheny tunnel at right; Gallitzin Tunnel (Haer no. PA-516) at left. - Pennsylvania Railroad, Allegheny Tunnel, Beneath Allegheny Mountain, east of Railroad Street, Gallitzin, Cambria County, PA

  14. AERIAL VIEW, LOOKING SOUTH, OF SHENANDOAHDIVES (MAYFLOWER) MINE PORTAL, IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    AERIAL VIEW, LOOKING SOUTH, OF SHENANDOAH-DIVES (MAYFLOWER) MINE PORTAL, IN SHADOW AT WIDENED END OF ROAD, THREE-EIGHTHS FROM THE BOTTOM. - Shenandoah-Dives Mill, 135 County Road 2, Silverton, San Juan County, CO

  15. View of the Colorado River Canyon showing lower portal road ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of the Colorado River Canyon showing lower portal road in background taken from the rim of Hoover Dam, view south - Hoover Dam, Spanning Colorado River at Route 93, Boulder City, Clark County, NV

  16. 163. VIEW OF TWO JOHNS MINE PORTAL FROM EAST. NOTE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    163. VIEW OF TWO JOHNS MINE PORTAL FROM EAST. NOTE WATER LINE ON BRIDGE; DEWATERING MINE SUPPLIED A PORTION OF THE MILL'S WATER SUPPLY. - Bald Mountain Gold Mill, Nevada Gulch at head of False Bottom Creek, Lead, Lawrence County, SD

  17. 3. East portal of Tunnel 24, contextual view to southwest, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. East portal of Tunnel 24, contextual view to southwest, 135mm lens. Note also Harriman Common Standard drain structure at right. - Central Pacific Transcontinental Railroad, Tunnel No. 24, Milepost 132.9, Applegate, Placer County, CA

  18. 1. West portal of Tunnel 25, contextual view to northeast ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. West portal of Tunnel 25, contextual view to northeast from Tunnel 24 (HAER CA-200), 135mm lens. - Central Pacific Transcontinental Railroad, Tunnel No. 25, Milepost 133.09, Applegate, Placer County, CA

  19. 6. Detail, vertical guides adjacent to east portal of Tunnel ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Detail, vertical guides adjacent to east portal of Tunnel 28, view to southwest, 135mm lens with electronic flash fill. - Central Pacific Transcontinental Railroad, Tunnel No. 28, Milepost 134.75, Applegate, Placer County, CA

  20. 7. Detail, machinery shed atop east portal of Tunnel 28, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Detail, machinery shed atop east portal of Tunnel 28, showing shaft and pulley system, 210mm lens with electronic flash fill. - Central Pacific Transcontinental Railroad, Tunnel No. 28, Milepost 134.75, Applegate, Placer County, CA

  1. 4. East portal of Tunnel 25, view to southwest from ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. East portal of Tunnel 25, view to southwest from west end of Tunnel 26 (HAER CA-202), 135mm lens. - Central Pacific Transcontinental Railroad, Tunnel No. 25, Milepost 133.09, Applegate, Placer County, CA

  2. Portal vein aneurysm demonstrated by blood pool SPECT.

    PubMed

    Fukui, H; Kashiwagi, T; Kimura, K; Goto, M; Takei, Y; Kasahara, A; Kawano, S; Fusamoto, H; Kozuka, T; Kamada, T

    1992-11-01

    Portal vein aneurysms are rare and are occasionally suggested by ultrasound and usually confirmed by invasive angiography. Such a case was diagnosed by scintigraphic studies, most importantly blood pool SPECT, which clearly separates it from hepatic cysts. PMID:1424375

  3. Eastern portal, looking W. Note hipped roof covered with wood ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Eastern portal, looking W. Note hipped roof covered with wood shingles, added in 1993. The hipped roof is unique in U.S. covered bridges. - Doe River Bridge, Spanning Doe River, Third Avenue, Elizabethton, Carter County, TN

  4. 26. Photocopy of photograph. VIEW, LOOKING SOUTHWEST, SHOWING NORTH PORTAL. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. Photocopy of photograph. VIEW, LOOKING SOUTHWEST, SHOWING NORTH PORTAL. Photographer unknown, ca. 1932. (Print in possession of the Washington County Highway Department.) - Hegeman-Hill Street Bridge, Spanning Batten Kill, .65 mile West of Greenwich, Easton, Washington County, NY

  5. 7. VIEW OF WEST WEB AND NORTH PORTAL OF 1886 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. VIEW OF WEST WEB AND NORTH PORTAL OF 1886 TRUSS FROM VALLEY STREET RAMP, LOOKING SOUTHEAST - Sixth Street Viaduct, Spanning Burlington Northern Railroad & Valley Street, Burlington, Des Moines County, IA

  6. 11. VIEW OF EAST WEB AND SOUTH PORTAL OF 1886 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. VIEW OF EAST WEB AND SOUTH PORTAL OF 1886 TRUSS, LOOKING NORTHWEST FROM MARKET STREET - Sixth Street Viaduct, Spanning Burlington Northern Railroad & Valley Street, Burlington, Des Moines County, IA

  7. 3. UPPER END, OR SOUTH PORTAL, OF THE WEHRLI TUNNEL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. UPPER END, OR SOUTH PORTAL, OF THE WEHRLI TUNNEL ON THE POWER CANAL Photographer: Walter J. Lubken, April 1, 1905 - Roosevelt Power Canal & Diversion Dam, Parallels Salt River, Roosevelt, Gila County, AZ

  8. South portal elevation with board and battan siding covering tympanum ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    South portal elevation with board and battan siding covering tympanum and sign reading "Swann bridge built in 1933". - Swann Bridge, Spanning Locust Fork of Black Warrior River, Swann Bridge Road, Cleveland, Blount County, AL

  9. 9. PORTAL ELEVATION, SOUTHWEST END OF BRIDGE, SHOWING COMPOSITION OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. PORTAL ELEVATION, SOUTHWEST END OF BRIDGE, SHOWING COMPOSITION OF TRUSS MEMBERS ALONG THE TRUSS - Seddon Island Scherzer Rolling Lift Bridge, Spanning Garrison Channel from Tampa to Seddon Island, Tampa, Hillsborough County, FL

  10. 22. PIER NO. IV DETAIL, WITH DETAIL OF SOUTHWEST PORTAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. PIER NO. IV DETAIL, WITH DETAIL OF SOUTHWEST PORTAL AND SOUTHEAST WEB OF THROUGH TRUSS; VIEW TO NORTH - Nebraska City Bridge, Spanning Missouri River near Highway 2 between Nebraska & Iowa, Nebraska City, Otoe County, NE

  11. Monthly Water Balance Model Portal for the United States

    NASA Astrophysics Data System (ADS)

    Hay, L.; Bock, A.; Markstrom, S. L.; McCabe, G. J., Jr.; Atkinson, D.

    2014-12-01

    The Monthly Water Balance Model (MWBM) portal delivers MWBM output generated for current and future climatic conditions for stream segments and hydrologic response units derived from the US Geological Survey's National Hydrologic Model Geospatial Fabric. The MWBM is a modular system that provides monthly estimates of components of the hydrologic cycle (e.g. streamflow, potential and actual evapotranspiration, snowpack, and storage) computed from mean monthly temperature, monthly total precipitation, latitude, and available soil water capacity. The MWBM portal can generate reports and graphics using simulations from more than 200 current and future climate scenarios at any location within the contiguous US. This presentation will introduce users to the MWBM portal and demonstrate how to access and download MWBM portal data.

  12. Detail of inside of inclined end post, with portal cross ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of inside of inclined end post, with portal cross bar member. - Phoenix Iron Company, French Creek Bridge, Spanning French Creek between Gay Street & Main Street, Phoenixville, Chester County, PA

  13. 46. View of access portal holes drilled to place steel ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    46. View of access portal holes drilled to place steel ties in Pleasant Dam buttresses. Photographer unknown, 1935. Source: Huber Collection. - Waddell Dam, On Agua Fria River, 35 miles northwest of Phoenix, Phoenix, Maricopa County, AZ

  14. 7. Detail of Minnesota (southeast) portal of bridge, from the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Detail of Minnesota (southeast) portal of bridge, from the southeast - Enloe Bridge No. 90021, Spanning Red River of North between Minnesota & North Dakota on County State Aid Highway 28, Wolverton, Wilkin County, MN

  15. 38. VIEW OF CONCRETE PORTAL OF MAIN DRIFT OPENING WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    38. VIEW OF CONCRETE PORTAL OF MAIN DRIFT OPENING WITH ERIC DELONY SERVING AS A SCALE FIGURE - Kaymoor Coal Mine, South side of New River, upstream of New River Gorge Bridge, Fayetteville, Fayette County, WV

  16. 2. BRIDGE APPROACH AND THREEQUARTER VIEW SHOWING PORTAL AND LONG ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. BRIDGE APPROACH AND THREE-QUARTER VIEW SHOWING PORTAL AND LONG ELEVATIONS - Kuhn's Fording Bridge, Spanning Conewago Creek on Township Road 552 (Hamilton & Reading townships), East Berlin, Adams County, PA

  17. The National Oceanic and Atmospheric Administration (NOAA) Climate Services Portal: A New Centralized Resource for Distributed Climate Information

    NASA Astrophysics Data System (ADS)

    Burroughs, J.; Baldwin, R.; Herring, D.; Lott, N.; Boyd, J.; Handel, S.; Niepold, F.; Shea, E.

    2010-09-01

    With the rapid rise in the development of Web technologies and climate services across NOAA, there has been an increasing need for greater collaboration regarding NOAA's online climate services. The drivers include the need to enhance NOAA's Web presence in response to customer requirements, emerging needs for improved decision-making capabilities across all sectors of society facing impacts from climate variability and change, and the importance of leveraging climate data and services to support research and public education. To address these needs, NOAA (during fiscal year 2009) embarked upon an ambitious program to develop a NOAA Climate Services Portal (NCS Portal). Four NOAA offices are leading the effort: 1) the NOAA Climate Program Office (CPO), 2) the National Ocean Service's Coastal Services Center (CSC), 3) the National Weather Service's Climate Prediction Center (CPC), and 4) the National Environmental Satellite, Data, and Information Service's (NESDIS) National Climatic Data Center (NCDC). Other offices and programs are also contributing in many ways to the effort. A prototype NCS Portal is being placed online for public access in January 2010, http://www.climate.gov. This website only scratches the surface of the many climate services across NOAA, but this effort, via direct user engagement, will gradually expand the scope and breadth of the NCS Portal to greatly enhance the accessibility and usefulness of NOAA's climate data and services.

  18. Portal Chronic Inflammation in Nonalcoholic Fatty Liver Disease

    PubMed Central

    Brunt, Elizabeth M.; Kleiner, David E.; Wilson, Laura A.; Unalp, Aynur; Behling, Cynthia E.; Lavine, Joel E.; Neuschwander-Tetri, Brent A.

    2009-01-01

    Untreated adult nonalcoholic fatty liver disease (NAFLD) is characterized by absent or mild portal chronic inflammation (CI); in the portal-based pediatric pattern of NAFLD, portal CI may be a predominant component. This study was undertaken to correlate clinical features with portal CI in the subjects enrolled in the NASH CRN. Methods Histology from central grading and clinical parameters temporally related to the biopsy were evaluated from 728 adults and 205 children. Results Sixty percent of adult biopsies had mild, 23% had more than mild, and 16% had no portal CI. In children, 76% had mild, 14% were more than mild, and 10% had no portal CI. In neither group were autoantibodies, elevated ALT, or generic use of “any” medications associated with the presence or degree of portal CI. Clinical features associated with “more than mild” in adults were older age (51 y v 44 y) (p<0.0001), female gender (p=0.001), higher BMI (p<0.0001), elevated insulin levels (median 20 v 14uU/ml) (p=0.001), higher HOMA-IR (median 5 v 3) (p<0.0001), and medications used for NAFLD (p=0.0004), diabetes (p<0.0001), and hypertension (p<0.0001). The same comparisons for “more than mild” v “none” in the pediatric biopsies showed only an association with younger age (12 y v 14 y) (p=0.01), but there was a trend favoring boys. There was no association with BMI, insulin or HOMA-IR. In both groups, lobular and portal inflammation scores had no association, but there was an association with a definite steatohepatitis diagnosis (p<0.0001 for both). Features in the adult biopsies associated with “more than mild” were steatosis amount (p=0.01and location (p<0.0001), presence of ballooning (p<0.0001), and advanced fibrosis (p<0.0001). In the pediatric biopsies, “more than mild” compared with “none” was associated with steatosis location (p=0.0008), and fibrosis score (p<0.0001), specifically, the pediatric (zone 1 accentuation) pattern (p<0.001) and portal

  19. 2. West portal of Tunnel 3, oblique view to northnorthwest, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. West portal of Tunnel 3, oblique view to north-northwest, 135mm lens. Note the simple concrete portal face and wingwalls, characteristic of the later (1923-27) period of construction on the Natron Cutoff. Note also the extreme surface spalling of the concrete, evidence of the severe freeze-thaw cycle at this elevation. - Southern Pacific Railroad Natron Cutoff, Tunnel 3, Milepost 537.77, Odell Lake, Klamath County, OR

  20. 1. East portal of Tunnel 4, view to west with ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. East portal of Tunnel 4, view to west with east portal of Tunnel 38 (HAER CA-211) visible in distance, 135mm lens with electronic flash fill. This tunnel was photographed to provide context, because even though somewhat enlarged, it illustrates the nature of the unlined hard rock tunnels typical of the original Central Pacific construction in 1868. - Central Pacific Transcontinental Railroad, Tunnel No. 4, Milepost 180.95, Cisco, Placer County, CA

  1. 8. Detail, east portal of Tunnel 41 inside Snowshed 33, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Detail, east portal of Tunnel 41 inside Snowshed 33, view to west-northwest, 135mm lens with electronic flash fill. The tiny white dot visible in the darkness of the tunnel is the west portal, two miles distant. The heavy steel beams carrying the concrete roof panels of the snowshed appear to be reused bridge girders. - Central Pacific Transcontinental Railroad, Tunnel No. 41, Milepost 193.3, Donner, Placer County, CA

  2. ELT Science Case Evaluation Using An HPC Portal

    NASA Astrophysics Data System (ADS)

    Linde, P.; Lindemann, J.

    2008-08-01

    A simulation package has been developed for testing science cases for the European Extremely Large Telescope. The application is capable of running in a grid environment using a simple plugin adaptation. Further, a user-friendly web based portal has been developed, allowing facilitated access to grid resources. The application gets access to portal controlled services, such as starting and monitoring the execution, as well as enabling user control and retrieval of the results.

  3. Endovascular Treatment of a Portal Vein Tear During TIPSS

    SciTech Connect

    Owen, Richard J.T.; Rose, John D.G.

    2000-03-15

    During a transjugular portosystemic stent-shunt (TIPSS) procedure a portal vein laceration occurred with subsequent intraperitoneal hemorrhage. A PTFE-covered nitinol stent was successfully placed eliminating the leak and creating a functioning portosystemic shunt. This case demonstrates both the importance of portal vein puncture more than 1 cm from the bifurcation and the necessity of maintaining a stock of available stent-grafts.

  4. Transtibial Versus Anteromedial Portal ACL Reconstruction

    PubMed Central

    Jennings, Jonathan Kelsie; Leas, Daniel; Fleischli, James E.; D’Alessandro, Donald; Peindl, Richard Dennis; Habet, Nahir A.; Piasecki, Dana P.

    2016-01-01

    Objectives: A number of studies suggest improved biomechanical and clinical results when ACL grafts are placed anatomically. Worldwide, the most common transtibial (TT) technique has been shown less anatomic than an anteromedial portal (AM) technique, though is much more familiar and less technically challenging. A hybrid transtibial approach (HTT) - using AM portal guidance of a flexible transtibial guide wire without knee hyperflexion - may offer anatomic graft placement while maintaining the relative ease of a transtibial technique. Our objective is to evaluate the anatomic and biomechanical performance of HTT, when compared to TT and AM approaches. Methods: A total of 36 paired, fresh-frozen human knees were used. 24 knees (12 pairs) - each using a standard tibial tunnel - underwent all three techniques (TT, AM, HTT) for femoral tunnel placement, with direct measurement of femoral insertional overlap and femoral tunnel length for each technique. The remaining 12 knees (6 pairs) were used to evaluate graft kinematics and tunnel orientation. Among these knees, 3 size-matched groups (four specimens each) were assigned to each of TT, AM and HTT techniques. Specimens were tested in quad-load induced extension from 90o to 10o of flexion with a distal weight used to simulate half-shank, ankle and foot passive load. Bony kinematics were assessed using a trakSTAR motion tracking system with three sensors installed in each femur and tibia. After femoral tunnel preparation, two sensors were installed in each tunnel to relate tunnel orientation and tunnel inlet location within the joint to the sensors used for motion tracking for the femur and tibia of each specimen. Bone-patellar-bone autografts were harvested from each specimen and used for the assigned reconstructive technique. Analysis included determination of ACL graft length changes, ACL-to-femoral tunnel angle and ACL-to-tibial tunnel angle at five flex/ext angles. Data was analyzed for three flex/ext tests on each

  5. Management of portal hypertension derived from uncommon causes

    PubMed Central

    Kim, Sung Hyun; Lee, Hae Min; Lee, Seung Ho; Won, Jong Yoon

    2016-01-01

    Portal hypertension can arise from any condition interfering with normal blood flow at any level within the portal system. Herein, we presented two uncommon cases of the portal hypertension and its treatment with brief literature review. A 71-year-old man who underwent right hemihepatectomy revealed a tumor recurrence adjacent to the inferior vena cava (IVC). After radiofrequency ablation (RFA) with lymph node dissection, he was referred for abdominal distension. The abdomen computed tomography scan showed severe ascites with a narrowing middle hepatic vein (MHV) and IVC around the RFA site. After insertion of two stents at the IVC and MHV, the ascites disappeared. Another 73-year-old man underwent right trisectionectomy of liver and segmental resection of the portal vein (PV). After operation, he underwent conservative management due to continuous abdominal ascites. The abdomen computed tomography scan showed severe ascites with obliteration of the left PV. After insertion of stent, the ascites disappeared. A decrease of the pressure gradient between the PV and IVC is one of the important treatment strategies for portal hypertension. Vascular stent is useful in the reduction of pressure gradient and thus, can be a treatment option for portal hypertension. PMID:27212996

  6. Spectroscopic classification of supernova candidates

    NASA Astrophysics Data System (ADS)

    Hodgkin, S. T.; Hall, A.; Fraser, M.; Campbell, H.; Wyrzykowski, L.; Kostrzewa-Rutkowska, Z.; Pietro, N.

    2014-09-01

    We report the spectroscopic classification of four supernovae at the 2.5m Isaac Newton Telescope on La Palma, using the Intermediate Dispersion Spectrograph and the R300V grating (3500-8000 Ang; ~6 Ang resolution).

  7. Spectroscopic optical coherence elastography

    PubMed Central

    Adie, Steven G.; Liang, Xing; Kennedy, Brendan F.; John, Renu; Sampson, David D.; Boppart, Stephen A.

    2010-01-01

    We present an optical technique to image the frequency-dependent complex mechanical response of a viscoelastic sample. Three-dimensional hyperspectral data, comprising two-dimensional B-mode images and a third dimension corresponding to vibration frequency, were acquired from samples undergoing external mechanical excitation in the audio-frequency range. We describe the optical coherence tomography (OCT) signal when vibration is applied to a sample and detail the processing and acquisition techniques used to extract the local complex mechanical response from three-dimensional data that, due to a wide range of vibration frequencies, possess a wide range of sample velocities. We demonstrate frequency-dependent contrast of the displacement amplitude and phase of a silicone phantom containing inclusions of higher stiffness. Measurements of an ex vivo tumor margin demonstrate distinct spectra between adipose and tumor regions, and images of displacement amplitude and phase demonstrated spatially-resolved contrast. Contrast was also observed in displacement amplitude and phase images of a rat muscle sample. These results represent the first demonstration of mechanical spectroscopy based on B-mode OCT imaging. Spectroscopic optical coherence elastography (S-OCE) provides a high-resolution imaging capability for the detection of tissue pathologies that are characterized by a frequency-dependent viscoelastic response. PMID:21164898

  8. Spectroscopic optical coherence elastography.

    PubMed

    Adie, Steven G; Liang, Xing; Kennedy, Brendan F; John, Renu; Sampson, David D; Boppart, Stephen A

    2010-12-01

    We present an optical technique to image the frequency-dependent complex mechanical response of a viscoelastic sample. Three-dimensional hyperspectral data, comprising two-dimensional B-mode images and a third dimension corresponding to vibration frequency, were acquired from samples undergoing external mechanical excitation in the audio-frequency range. We describe the optical coherence tomography (OCT) signal when vibration is applied to a sample and detail the processing and acquisition techniques used to extract the local complex mechanical response from three-dimensional data that, due to a wide range of vibration frequencies, possess a wide range of sample velocities. We demonstrate frequency-dependent contrast of the displacement amplitude and phase of a silicone phantom containing inclusions of higher stiffness. Measurements of an ex vivo tumor margin demonstrate distinct spectra between adipose and tumor regions, and images of displacement amplitude and phase demonstrated spatially-resolved contrast. Contrast was also observed in displacement amplitude and phase images of a rat muscle sample. These results represent the first demonstration of mechanical spectroscopy based on B-mode OCT imaging. Spectroscopic optical coherence elastography (S-OCE) provides a high-resolution imaging capability for the detection of tissue pathologies that are characterized by a frequency-dependent viscoelastic response. PMID:21164898

  9. NASA GES DISC Hurricane Web Portal

    NASA Astrophysics Data System (ADS)

    Liu, Z.; Leptoukh, G.; Ostrenga, D.; Rui, H.; Hulka, J.; Carlaw, L.

    2006-12-01

    This presentation will describe recent activities at the NASA Goddard Earth Sciences (GES) Data and Information Services Center (DISC) to support hurricane monitoring, research and outreach activities. A newly developed web portal (URL: http://disc.sci.gsfc.nasa.gov/hurricane/) is designed for viewing and studying hurricanes by utilizing various measurements by NASA remote-sensing instruments. The portal consists of five main components: - Current conditions (in pre-selected regions and updated daily): the latest maps, animation and profiles from NASA satellites. At present, images or plots created using data from TRMM, AIRS, MODIS, MLS and CloudSat are available. Later, data from OMI and other instruments will be added. A new feature will be added to allow users to easily download/subset data associated with these images. - Past hurricane archive: maps, animation and profiles of past hurricanes were created using data from TRMM, AIRS, MODIS, MLS and CloudSat, allowing users to explore past hurricanes and download/subset data if necessary. - Science focus: examples/stories describing data usage in hurricane monitoring and research - Tools: descriptions and links of a number of in-house developed tools for hurricane exploration and event-based data ordering. For example, the GES-DISC Interactive Online Visualization ANd aNalysis Infrastructure (Giovanni, URL: http://giovanni.gsfc.nasa.gov), a series of online visualization and analysis systems, allows users to access data ranging from near-real-time to historical archives and generate customized analysis maps, plots and data on the fly over the Internet. A hurricane instance of Giovanni is under development. Mirador (URL: http://g0dup05u.ecs.nasa.gov/OPS/mirador/) is another in-house developed tool that offers a simplified interface for searching, browsing, and ordering Earth science data at NASA GES DICS. Users can do event based (e.g., entering a hurricane name) search and order data. - Hurricane viewer: provides

  10. [A case of portal vein stenting for portal vein stenosis due to pancreatic cancer recurrence after pancreatoduodenectomy].

    PubMed

    Sawatsubashi, Takahiro; Morioka, Nobuhiro; Shimizu, Takao; Nakatsuka, Hideki

    2014-11-01

    We report a case of portal vein stenosis due to pancreatic cancer recurrence that was successfully treated with intravenous stent implantation. The patient was a 70-year-old man who had undergone a subtotal stomach-preserving pancreatoduodenectomy with the modified Child method for pancreatic cancer. He was readmitted due to melena, dorsal pain, and severe ascites 8 months after the operation. Computed tomography (CT) findings revealed that pancreatic cancer recurrence had narrowed the portal vein. Neither gastrointestinal nor colon endoscopy could locate the source of gastrointestinal bleeding. Bleeding from the varices increased, and a hepatopetal collateral was considered to be the cause. We therefore placed an intravenous stent at the site of portal vein stenosis, by the transileocolic portal vein. After the stent placement, no further gastrointestinal hemorrhagic episodes occurred. PMID:25731472

  11. MeCaSDa and ECaSDa: Methane and ethene calculated spectroscopic databases for the virtual atomic and molecular data centre

    NASA Astrophysics Data System (ADS)

    Ba, Yaye Awa; Wenger, Christian; Surleau, Romain; Boudon, Vincent; Rotger, Maud; Daumont, Ludovic; Bonhommeau, David A.; Tyuterev, Vladimir G.; Dubernet, Marie-Lise

    2013-11-01

    Two spectroscopic relational databases, denoted MeCaSDa and ECaSDa, have been implemented for methane and ethene, and included in VAMDC (Virtual Atomic and Molecular Data Centre, http://portal.vamdc.eu/vamdc_portal/home.seam). These databases collect calculated spectroscopic data from the accurate analyses previously performed for the electronic ground state of methane, ethene, and some of their isotopologues: 12CH4, 13CH4, and 12C2H4. Both infrared absorption and Raman scattering lines are included. The polyad structures are reported and the transitions are precisely described by their energy, their intensity and the full description of the lower and upper states involved in the transitions. The relational schemas of ECaSDa and MeCaSDa databases are equivalent and optimised to enable the better compromise between data retrieval and compatibility with the XSAMS (XML Schema for Atoms, Molecules, and Solids) format adopted within the VAMDC European project.

  12. Detection and classification of concealed weapons using a magnetometer-based portal

    NASA Astrophysics Data System (ADS)

    Kotter, Dale K.; Roybal, Lyle G.; Polk, Robert E.

    2002-08-01

    A concealed weapons detection technology was developed through the support of the National Institute of Justice (NIJ) to provide a non intrusive means for rapid detection, location, and archiving of data (including visual) of potential suspects and weapon threats. This technology, developed by the Idaho National Engineering and Environmental Laboratory (INEEL), has been applied in a portal style weapons detection system using passive magnetic sensors as its basis. This paper will report on enhancements to the weapon detection system to enable weapon classification and to discriminate threats from non-threats. Advanced signal processing algorithms were used to analyze the magnetic spectrum generated when a person passes through a portal. These algorithms analyzed multiple variables including variance in the magnetic signature from random weapon placement and/or orientation. They perform pattern recognition and calculate the probability that the collected magnetic signature correlates to a known database of weapon versus non-weapon responses. Neural networks were used to further discriminate weapon type and identify controlled electronic items such as cell phones and pagers. False alarms were further reduced by analyzing the magnetic detector response by using a Joint Time Frequency Analysis digital signal processing technique. The frequency components and power spectrum for a given sensor response were derived. This unique fingerprint provided additional information to aid in signal analysis. This technology has the potential to produce major improvements in weapon detection and classification.

  13. Infrared Spectroscopic Imaging: The Next Generation

    PubMed Central

    Bhargava, Rohit

    2013-01-01

    Infrared (IR) spectroscopic imaging seemingly matured as a technology in the mid-2000s, with commercially successful instrumentation and reports in numerous applications. Recent developments, however, have transformed our understanding of the recorded data, provided capability for new instrumentation, and greatly enhanced the ability to extract more useful information in less time. These developments are summarized here in three broad areas— data recording, interpretation of recorded data, and information extraction—and their critical review is employed to project emerging trends. Overall, the convergence of selected components from hardware, theory, algorithms, and applications is one trend. Instead of similar, general-purpose instrumentation, another trend is likely to be diverse and application-targeted designs of instrumentation driven by emerging component technologies. The recent renaissance in both fundamental science and instrumentation will likely spur investigations at the confluence of conventional spectroscopic analyses and optical physics for improved data interpretation. While chemometrics has dominated data processing, a trend will likely lie in the development of signal processing algorithms to optimally extract spectral and spatial information prior to conventional chemometric analyses. Finally, the sum of these recent advances is likely to provide unprecedented capability in measurement and scientific insight, which will present new opportunities for the applied spectroscopist. PMID:23031693

  14. Spectroscopic investigation of protein corona

    NASA Astrophysics Data System (ADS)

    Choudhary, Poonam

    Nanotechnology has revolutionalized the landscape of modern science and technology, including materials, electronics, therapeutics, bioimaging, sensing, and the environment. Research in the past decade has examined the fate of nanomaterials in vitro and in vivo, as well as the interactions between nanoparticles and biological and ecosystems using primarily toxicological and ecotoxicological approaches. However, due to the versatility in the physical and physicochemical properties of nanoparticles, and due to the vast complexity of their hosting systems, the solubility, transformation, and biocompatibility of nanomaterials are still poorly understood. Nanotechnology has been undergoing tremendous development in recent decades, driven by realized perceived applications of nanomaterials in electronics, therapeutics, imaging, sensing, environmental remediation, and consumer products. Nanoparticles on entering the blood stream undergo an identity change, they become coated with proteins. There are different kind of proteins present in blood. Proteins compete for getting coated over the surface of nanoparticle and this whole entity of proteins coated over nanoparticle surface is called Protein Corona. Proteins tightly bound to the surface of nanoparticle form hard corona and the ones loosely bound on the outer surface form soft corona. This dissertation is aimed at spectroscopic investigation of Protein Corona. Chapter I of this dissertation offers a comprehensive review of the literature based on nanomaterials with the focus on carbon based nanomaterilas and introduction to Protein Corona. Chapter II is based different methods used for Graphene Synthesis,different types of defects and doping. In Chapter III influence of defects on Graphene Protein Corona was investigated. Chapter IV is based on the study of Apoptosis induced cell death by Gold and silver nanoparticles. In vitro study of effect of Protein Corona on toxicity of cells was done.

  15. The JPL GRIP Portal - Serving Near Real-time Observation and Model Forecast for Hurricane Study

    NASA Astrophysics Data System (ADS)

    Li, P.; Hristova-Veleva, S. M.; Turk, F. J.; Vu, Q.; Knosp, B. W.; Lambrigtsen, B.; Poulsen, W. L.; Shen, T. J.; Licata, S. J.

    2010-12-01

    from many different sources and with different formats, to make the data available with minimal latency, and to satisfy users with different bandwidth requirements. In this paper, we will talk about the technologies behind the portal, the common problems we encountered during the field experiment and how we solved those problems.

  16. Mapping and Modeling Web Portal to Advance Global Monitoring and Climate Research

    NASA Astrophysics Data System (ADS)

    Chang, G.; Malhotra, S.; Bui, B.; Sadaqathulla, S.; Goodale, C. E.; Ramirez, P.; Kim, R. M.; Rodriguez, L.; Law, E.

    2011-12-01

    principal investigators to share their research and analysis seamlessly. In addition, this extension will allow users to easily share their tools and data, and to enrich their mapping and analysis experiences. In this talk, we will describe the advanced data management and portal technologies used to power this collaborative environment. We will further illustrate how this environment can enable, enhance and advance global monitoring and climate research.

  17. Time Series Evaluation of Portal Monitor Data

    SciTech Connect

    Robinson, Sean M.; Bender, Sarah E.; Lopresti, Charles A.; Woodring, Mitchell L.

    2008-12-08

    Radiation portal monitors screen cargo and personal vehicle traffic at international border crossings to detect and interdict illicit sources which may be present in the commerce stream. One difficulty faced by RPM systems is the prospect of false alarms, or undesired alarms due to background fluctuation, or Naturally-Occurring Radioactive Material (NORM) sources in the commerce stream. In general, NORM alarms represent a significant fraction of the nuisance alarms at international border crossings, particularly with Polyvinyl-Toluene (PVT) RPM detectors, which have only very weak spectral differentiation capability. With PVT detectors, the majority of detected photon events fall within the Compton continuum of the material, allowing for very little spectral information to be preserved [1]. Previous work has shown that these detectors can be used for limited spectroscopy, utilizing around 8 spectral bins to further differentiate some NORM and other nuisance sources [2]. NaI based systems achieve much more detailed spectral resolution from each measurement of a source, but still combine all measurements over a vehicle's occupancy in order to arrive at a spectrum to be analyzed.

  18. ProPortal: A Database for Prochlorococcus

    DOE Data Explorer

    Huang, Katherine [Chisholm lab, MIT

    Prochlorococcus is a marine cyanobacterium that numerically dominates the mid-latitude oceans, and is the smallest known oxygenic phototroph. All isolates described thus far can be assigned to either a tightly clustered high-light (HL) adapted clade, or a more divergent low-light (LL) adapted group. They are closely related to, but distinct from, marine Synechococcus. The genomes of 12 strains have been sequenced and they range in size from 1.6 to 2.6 Mbp. They represent diverse lineages, spanning the rRNA diversity (97 to 99.93% similarity) of cultured representatives of this group. Our analyses of these genomes inform our understanding of how adaptation occurs in the oceans along gradients of light, nutrients, and other environmental factors, providing essential context for interpreting rapidly expanding metagenomic datasets. [Copied from http://proportal.mit.edu/project/prochlorococcus/] ProPortal allows users to browse and search genome date for not only Prochlorococcus, but Cyanophage and Synechococcus. Microarray data, environmental cell concentration data, and metagenome information are also available.

  19. Overview of Portal Monitoring at Border Crossings

    SciTech Connect

    Geelhood, Bruce D.; Ely, James H.; Hansen, Randy R.; Kouzes, Richard T.; Schweppe, John E.; Warner, Ray A.

    2003-10-01

    The Bureau of Customs and Border Protection has the task of interdicting illicit radioactive material at ports of entry. Items of concern include radiation dispersal devices (RDD), nuclear warheads, and special nuclear material (SNM). The preferred survey method screens all vehicles in primary and diverts questionable vehicles to secondary. This requires high detection probability in primary while not overwhelming secondary with alarms, which could include naturally occurring radioactive material (NORM) found in acceptable cargo and radionuclides used in medical procedures. Sensitive alarm algorithms must accommodate the baseline depression observed whenever a vehicle enters the portal. Energy-based algorithms can effectively use the crude energy information available from a plastic scintillator to distinguish NORM from SNM. Whenever NORM cargo limits the alarm threshold, energy-based algorithms produce significantly better detection probabilities for small SNM sources than gross-count algorithms. Algorithms can be best evaluated using a large empirical data set to 1) calculate false alarm probabilities, 2) select sigma-level thresholds for operationally acceptable false alarm rates, and 3) determine detection probabilities for marginally detectable pseudo sources of SNM.

  20. DESM: portal for microbial knowledge exploration systems

    PubMed Central

    Salhi, Adil; Essack, Magbubah; Radovanovic, Aleksandar; Marchand, Benoit; Bougouffa, Salim; Antunes, Andre; Simoes, Marta Filipa; Lafi, Feras F.; Motwalli, Olaa A.; Bokhari, Ameerah; Malas, Tariq; Amoudi, Soha Al; Othum, Ghofran; Allam, Intikhab; Mineta, Katsuhiko; Gao, Xin; Hoehndorf, Robert; C. Archer, John A.; Gojobori, Takashi; Bajic, Vladimir B.

    2016-01-01

    Microorganisms produce an enormous variety of chemical compounds. It is of general interest for microbiology and biotechnology researchers to have means to explore information about molecular and genetic basis of functioning of different microorganisms and their ability for bioproduction. To enable such exploration, we compiled 45 topic-specific knowledgebases (KBs) accessible through DESM portal (www.cbrc.kaust.edu.sa/desm). The KBs contain information derived through text-mining of PubMed information and complemented by information data-mined from various other resources (e.g. ChEBI, Entrez Gene, GO, KOBAS, KEGG, UniPathways, BioGrid). All PubMed records were indexed using 4 538 278 concepts from 29 dictionaries, with 1 638 986 records utilized in KBs. Concepts used are normalized whenever possible. Most of the KBs focus on a particular type of microbial activity, such as production of biocatalysts or nutraceuticals. Others are focused on specific categories of microorganisms, e.g. streptomyces or cyanobacteria. KBs are all structured in a uniform manner and have a standardized user interface. Information exploration is enabled through various searches. Users can explore statistically most significant concepts or pairs of concepts, generate hypotheses, create interactive networks of associated concepts and export results. We believe DESM will be a useful complement to the existing resources to benefit microbiology and biotechnology research. PMID:26546514

  1. DESM: portal for microbial knowledge exploration systems.

    PubMed

    Salhi, Adil; Essack, Magbubah; Radovanovic, Aleksandar; Marchand, Benoit; Bougouffa, Salim; Antunes, Andre; Simoes, Marta Filipa; Lafi, Feras F; Motwalli, Olaa A; Bokhari, Ameerah; Malas, Tariq; Amoudi, Soha Al; Othum, Ghofran; Allam, Intikhab; Mineta, Katsuhiko; Gao, Xin; Hoehndorf, Robert; C Archer, John A; Gojobori, Takashi; Bajic, Vladimir B

    2016-01-01

    Microorganisms produce an enormous variety of chemical compounds. It is of general interest for microbiology and biotechnology researchers to have means to explore information about molecular and genetic basis of functioning of different microorganisms and their ability for bioproduction. To enable such exploration, we compiled 45 topic-specific knowledgebases (KBs) accessible through DESM portal (www.cbrc.kaust.edu.sa/desm). The KBs contain information derived through text-mining of PubMed information and complemented by information data-mined from various other resources (e.g. ChEBI, Entrez Gene, GO, KOBAS, KEGG, UniPathways, BioGrid). All PubMed records were indexed using 4,538,278 concepts from 29 dictionaries, with 1 638 986 records utilized in KBs. Concepts used are normalized whenever possible. Most of the KBs focus on a particular type of microbial activity, such as production of biocatalysts or nutraceuticals. Others are focused on specific categories of microorganisms, e.g. streptomyces or cyanobacteria. KBs are all structured in a uniform manner and have a standardized user interface. Information exploration is enabled through various searches. Users can explore statistically most significant concepts or pairs of concepts, generate hypotheses, create interactive networks of associated concepts and export results. We believe DESM will be a useful complement to the existing resources to benefit microbiology and biotechnology research. PMID:26546514

  2. The Integrate Student Portal: Online Resources to Prepare Students for the Workforce of a Sustainable Future

    NASA Astrophysics Data System (ADS)

    Bruckner, M. Z.; Manduca, C. A.; Egger, A. E.; Macdonald, H.

    2014-12-01

    The InTeGrate Student Portal is a suite of web pages that utilize InTeGrate resources to support student success by providing undergraduates with tools and information necessary to be proactive in their career choices and development. Drawn from various InTeGrate workshops and programming, the Portal organizes these resources to illuminate a variety of career opportunities and pathways to both traditional and non-traditional jobs that support a sustainable future. Informed from a variety of sources including employers, practitioners, faculty, students, reports, and articles, the pages explore five facets: (1) sustainability across the disciplines, (2) workforce preparation, (3) professional communication, (4) teaching and teaching careers, and (5) the future of green research and technology. The first three facets explore how sustainability is integrated across disciplines and how sustainability and 'green' jobs are available in a wide range of traditional and non-traditional workplaces within and beyond science. They provide students guidance in preparing for this sustainability workforce, including where to learn about jobs and how to pursue them, advice for strengthening their job applications, and how to build a set of skills that employers seek. This advice encompasses classroom skills as well as those acquired and strengthened as part of extracurricular or workplace experiences. The fourth facet, aimed at teaching assistants with little or no experience as well as at students who are interested in pursuing teaching as a career, provides information and resources about teaching. The fifth facet explores future directions of technology and the need for innovations in the workforce of the future to address sustainability issues. We seek your input and invite you to explore the Portal at: serc.carleton.edu/integrate/students/

  3. Soft tissue imaging with photon counting spectroscopic CT

    NASA Astrophysics Data System (ADS)

    Shikhaliev, Polad M.

    2015-03-01

    The purpose of this work was experimental investigation of photon counting spectroscopic CT (PCS-CT) imaging of anatomical soft tissue with clinically relevant size. The imaging experiments were performed using a spectroscopic CT system based on CdZnTe photon counting detector with two rows of pixels, 256 pixels in each row, 1  ×  1 mm2 pixel size, and 25.6 cm detector length. The detector could split the x-ray energy spectrum to 5 regions (energy bins), and acquire 5 multi-energy (spectroscopic) CT images in a single CT scan. A sample of round shaped anatomical soft tissue of 14 cm diameter including lean and fat was used for imaging. To avoid the negative effect of anatomical noise on quantitative analysis, a spectroscopic CT phantom with tissue equivalent solid materials was used. The images were acquired at 60, 90, and 120 kVp tube voltages, and spectroscopic image series were acquired with 3 and 5 energy bins. Spectroscopic CT numbers were introduced and used to evaluate an energy selective image series. The anatomical soft tissue with 14 cm diameter was visualized with good quality and without substantial artifacts by the photon counting spectroscopic CT system. The effects of the energy bin crosstalk on spectroscopic CT numbers were quantified and analyzed. The single and double slice PCS-CT images were acquired and compared. Several new findings were observed, including the effect of soft tissue non-uniformity on image artifacts, unique status of highest energy bin, and material dependent visualization in spectroscopic image series. Fat-lean decomposition was performed using dual energy subtraction and threshold segmentation methods, and compared. Using K-edge filtered x-rays improved fat-lean decomposition as compared to conventional x-rays. Several new and important aspects of the PCS-CT were investigated. These include imaging soft tissue with clinically relevant size, single- and double-slice PCS-CT imaging, using spectroscopic CT

  4. Soft tissue imaging with photon counting spectroscopic CT.

    PubMed

    Shikhaliev, Polad M

    2015-03-21

    The purpose of this work was experimental investigation of photon counting spectroscopic CT (PCS-CT) imaging of anatomical soft tissue with clinically relevant size. The imaging experiments were performed using a spectroscopic CT system based on CdZnTe photon counting detector with two rows of pixels, 256 pixels in each row, 1  ×  1 mm(2) pixel size, and 25.6 cm detector length. The detector could split the x-ray energy spectrum to 5 regions (energy bins), and acquire 5 multi-energy (spectroscopic) CT images in a single CT scan. A sample of round shaped anatomical soft tissue of 14 cm diameter including lean and fat was used for imaging. To avoid the negative effect of anatomical noise on quantitative analysis, a spectroscopic CT phantom with tissue equivalent solid materials was used. The images were acquired at 60, 90, and 120 kVp tube voltages, and spectroscopic image series were acquired with 3 and 5 energy bins. Spectroscopic CT numbers were introduced and used to evaluate an energy selective image series. The anatomical soft tissue with 14 cm diameter was visualized with good quality and without substantial artifacts by the photon counting spectroscopic CT system. The effects of the energy bin crosstalk on spectroscopic CT numbers were quantified and analyzed. The single and double slice PCS-CT images were acquired and compared. Several new findings were observed, including the effect of soft tissue non-uniformity on image artifacts, unique status of highest energy bin, and material dependent visualization in spectroscopic image series. Fat-lean decomposition was performed using dual energy subtraction and threshold segmentation methods, and compared. Using K-edge filtered x-rays improved fat-lean decomposition as compared to conventional x-rays. Several new and important aspects of the PCS-CT were investigated. These include imaging soft tissue with clinically relevant size, single- and double-slice PCS-CT imaging, using spectroscopic CT

  5. Dosimetric verification of radiation therapy including intensity modulated treatments, using an amorphous-silicon electronic portal imaging device

    NASA Astrophysics Data System (ADS)

    Chytyk-Praznik, Krista Joy

    Radiation therapy is continuously increasing in complexity due to technological innovation in delivery techniques, necessitating thorough dosimetric verification. Comparing accurately predicted portal dose images to measured images obtained during patient treatment can determine if a particular treatment was delivered correctly. The goal of this thesis was to create a method to predict portal dose images that was versatile and accurate enough to use in a clinical setting. All measured images in this work were obtained with an amorphous silicon electronic portal imaging device (a-Si EPID), but the technique is applicable to any planar imager. A detailed, physics-motivated fluence model was developed to characterize fluence exiting the linear accelerator head. The model was further refined using results from Monte Carlo simulations and schematics of the linear accelerator. The fluence incident on the EPID was converted to a portal dose image through a superposition of Monte Carlo-generated, monoenergetic dose kernels specific to the a-Si EPID. Predictions of clinical IMRT fields with no patient present agreed with measured portal dose images within 3% and 3 mm. The dose kernels were applied ignoring the geometrically divergent nature of incident fluence on the EPID. A computational investigation into this parallel dose kernel assumption determined its validity under clinically relevant situations. Introducing a patient or phantom into the beam required the portal image prediction algorithm to account for patient scatter and attenuation. Primary fluence was calculated by attenuating raylines cast through the patient CT dataset, while scatter fluence was determined through the superposition of pre-calculated scatter fluence kernels. Total dose in the EPID was calculated by convolving the total predicted incident fluence with the EPID-specific dose kernels. The algorithm was tested on water slabs with square fields, agreeing with measurement within 3% and 3 mm. The

  6. Portosystemic shunting in portal hypertension: evaluation with portal scintigraphy with transrectally administered I-123 IMP

    SciTech Connect

    Kashiwagi, T.; Azuma, M.; Ikawa, T.; Takehara, T.; Matsuda, H.; Yoshioka, H.; Mitsutani, N.; Koizumi, T.; Kimura, K.

    1988-10-01

    Portosystemic shunting was evaluated with rectal administration of iodine-123 iodoamphetamine (IMP) in seven patients without liver disease and 53 patients with liver cirrhosis. IMP (2-3 mCi (74-111 MBq)) was administered to the rectum through a catheter. Images of the chest and abdomen were obtained for up to 60 minutes with a scintillation camera interfaced with a computer. In all patients, images of the liver and/or lungs were observed within 5-10 minutes and became clear with time. In patients without liver disease, only liver images could be obtained, whereas the lung was visualized with or without the liver in all patients with liver cirrhosis. The portosystemic shunt index was calculated by dividing counts of lungs by counts of liver and lung. These values were significantly higher in liver cirrhosis, especially in the decompensated stage. Transrectal portal scintigraphy with IMP appears to be a useful method for noninvasive and quantitative evaluation of portosystemic shunting in portal hypertension.

  7. IOOS Data Portals and Uniform On-line Browse Capabilities

    NASA Astrophysics Data System (ADS)

    Howard, M.; Currier, R. D.; Kobara, S.; Gayanilo, F.

    2015-12-01

    The Gulf of Mexico Coastal Ocean Observing System Regional Association (GCOOS-RA) is one of eleven Regional Associations organized under the NOAA-led U.S. Integrated Ocean Observing System (IOOS) Program Office. Each of the RAs operate standards-based regional data portals designed to aggregate near real-time and historical observed data and modeled outputs from distributed providers and to offer these and derived products in standardized ways to a diverse set of users. The RA's portals are based on the IOOS Data and Communications Plan which describes the functional elements needed for an interoperable system. One of these elements is called "Uniform On-line Browse" which is an informational service designed primarily to visualize the inventory of a portal. An on-line browse service supports the end user's need to discover what parameters are available, to learn the spatial and temporal extend of the holdings, and to examine the character of the data (e.g, variability, gappiness, etc). These pieces of information help the end user decide if the data are fit for his/her purpose and to construct valid data requests. Note that on-line browse is a distinctly different activity than data analysis because it seeks to yield knowledge about the inventory and not about what the data mean. "Uniform" on-line browse is a service that takes advantage of the standardization of the data portal's data access points. Most portals represent station locations on a map. This is a view of the data inventory but these plots are rarely generated by pulling data through the standards-based services offered to the end users but through methods only available to the portal programmers. This work will present results of Uniform On-line browse tools developed within GCOOS-RA and their applicability to other RA portals.

  8. Adrenal dysfunction in portal hypertensive rats with acute hemorrhage.

    PubMed

    Lee, Fa-Yauh; Wang, Sun-Sang; Tsai, Ming-Hung; Huang, Hui-Chun; Lin, Han-Chieh; Lee, Shou-Dong

    2014-01-01

    Nitric oxide (NO) participates in shock and poorer portal hypotensive effect to vasoconstrictors in portal hypertension with hemorrhage, the so-called splanchnic hyposensitivity. Relative adrenal insufficiency accompanies hemorrhagic shock and is found in liver disease, the 'hepatoadrenal syndrome', but the relevant interactions remain unsettled. Portal hypertensive rats were induced by partial portal vein ligation (PVL). Experiments were performed on the 14th day post PVL: (I) ACTH stimulation test for rats without or with hemorrhage; (II) Glypressin response (mean arterial pressure, MAP; portal pressure, PP) in rats (a) without hemorrhage or with hemorrhage, injected with (b) distilled water (DW), (c) dexamethasone 3 mg/kg; (III) To survey the dose-dependent effects of glucocorticoid without being confounded by endogenous adrenal hormone, glypressin response was surveyed in PVL rats with adrenalectomy: (a) without hemorrhage or with hemorrhage, injected with (b) DW; (c) dexamethasone 3 mg/kg; (d) dexamethasone 5 mg/kg. Plasma tumor necrosis factor-α (TNF-α) concentrations and abdominal aorta (AA), superior mesenteric artery (SMA) NO synthases (NOS) mRNA expressions were determined. The results showed that ACTH induced corticosterone release similarly in PVL rats with or without hemorrhage. In bleeding PVL rats, dexamethasone (1) down-regulated AA NOS and enhanced glypressin-induced MAP elevation; (2) did not influence glypressin-induced PP reduction; (3) reduced TNF-α. In bleeding PVL and adrenalectomized rats, high-dose dexamethasone (1) down-regulated AA/SMA NOS; (2) enhanced glypressin-induced MAP elevation and PP reduction; (3) reduced TNF-α. In conclusion, bleeding portal hypertensive rats failed to enhance corticosterone release, suggesting a relative adrenal insufficiency. High-dose dexamethasone reversed systemic hypotension and splanchnic hyporesponsiveness to glypressin in adrenalectomized PVL rats accompanied by TNF-α and NOS down

  9. Experimental verification of a portal dose prediction model

    SciTech Connect

    Elmpt, W.J.C. van; Nijsten, S.M.J.J.G.; Mijnheer, B.J.; Minken, A.W.H.

    2005-09-15

    Electronic portal imaging devices (EPIDs) can be used to measure a two-dimensional (2D) dose distribution behind a patient, thus allowing dosimetric treatment verification. For this purpose we experimentally assessed the accuracy of a 2D portal dose prediction model based on pencil beam scatter kernels. A straightforward derivation of these pencil beam scatter kernels for portal dose prediction models is presented based on phantom measurements. The model is able to predict the 2D portal dose image (PDI) behind a patient, based on a PDI without the patient in the beam in combination with the radiological thickness of the patient, which requires in addition a PDI with the patient in the beam. To assess the accuracy of portal dose and radiological thickness values obtained with our model, various types of homogeneous as well as inhomogeneous phantoms were irradiated with a 6 MV photon beam. With our model we are able to predict a PDI with an accuracy better than 2% (mean difference) if the radiological thickness of the object in the beam is symmetrically situated around the isocenter. For other situations deviations up to 3% are observed for a homogeneous phantom with a radiological thickness of 17 cm and a 9 cm shift of the midplane-to-detector distance. The model can extract the radiological thickness within 7 mm (maximum difference) of the actual radiological thickness if the object is symmetrically distributed around the isocenter plane. This difference in radiological thickness is related to a primary portal dose difference of 3%. It can be concluded that our model can be used as an easy and accurate tool for the 2D verification of patient treatments by comparing predicted and measured PDIs. The model is also able to extract the primary portal dose with a high accuracy, which can be used as the input for a 3D dose reconstruction method based on back-projection.

  10. Adrenal Dysfunction in Portal Hypertensive Rats with Acute Hemorrhage

    PubMed Central

    Lee, Fa-Yauh; Wang, Sun-Sang; Lin, Han-Chieh; Lee, Shou-Dong

    2014-01-01

    Nitric oxide (NO) participates in shock and poorer portal hypotensive effect to vasoconstrictors in portal hypertension with hemorrhage, the so-called splanchnic hyposensitivity. Relative adrenal insufficiency accompanies hemorrhagic shock and is found in liver disease, the ‘hepatoadrenal syndrome’, but the relevant interactions remain unsettled. Portal hypertensive rats were induced by partial portal vein ligation (PVL). Experiments were performed on the 14th day post PVL: (I) ACTH stimulation test for rats without or with hemorrhage; (II) Glypressin response (mean arterial pressure, MAP; portal pressure, PP) in rats (a) without hemorrhage or with hemorrhage, injected with (b) distilled water (DW), (c) dexamethasone 3 mg/kg; (III) To survey the dose-dependent effects of glucocorticoid without being confounded by endogenous adrenal hormone, glypressin response was surveyed in PVL rats with adrenalectomy: (a) without hemorrhage or with hemorrhage, injected with (b) DW; (c) dexamethasone 3 mg/kg; (d) dexamethasone 5 mg/kg. Plasma tumor necrosis factor-α (TNF-α) concentrations and abdominal aorta (AA), superior mesenteric artery (SMA) NO synthases (NOS) mRNA expressions were determined. The results showed that ACTH induced corticosterone release similarly in PVL rats with or without hemorrhage. In bleeding PVL rats, dexamethasone (1) down-regulated AA NOS and enhanced glypressin-induced MAP elevation; (2) did not influence glypressin-induced PP reduction; (3) reduced TNF-α. In bleeding PVL and adrenalectomized rats, high-dose dexamethasone (1) down-regulated AA/SMA NOS; (2) enhanced glypressin-induced MAP elevation and PP reduction; (3) reduced TNF-α. In conclusion, bleeding portal hypertensive rats failed to enhance corticosterone release, suggesting a relative adrenal insufficiency. High-dose dexamethasone reversed systemic hypotension and splanchnic hyporesponsiveness to glypressin in adrenalectomized PVL rats accompanied by TNF-α and NOS down

  11. Denoising portal images by means of wavelet techniques

    NASA Astrophysics Data System (ADS)

    Gonzalez Lopez, Antonio Francisco

    Portal images are used in radiotherapy for the verification of patient positioning. The distinguishing feature of this image type lies in its formation process: the same beam used for patient treatment is used for image formation. The high energy of the photons used in radiotherapy strongly limits the quality of portal images: Low contrast between tissues, low spatial resolution and low signal to noise ratio. This Thesis studies the enhancement of these images, in particular denoising of portal images. The statistical properties of portal images and noise are studied: power spectra, statistical dependencies between image and noise and marginal, joint and conditional distributions in the wavelet domain. Later, various denoising methods are applied to noisy portal images. Methods operating in the wavelet domain are the basis of this Thesis. In addition, the Wiener filter and the non local means filter (NLM), operating in the image domain, are used as a reference. Other topics studied in this Thesis are spatial resolution, wavelet processing and image processing in dosimetry in radiotherapy. In this regard, the spatial resolution of portal imaging systems is studied; a new method for determining the spatial resolution of the imaging equipments in digital radiology is presented; the calculation of the power spectrum in the wavelet domain is studied; reducing uncertainty in film dosimetry is investigated; a method for the dosimetry of small radiation fields with radiochromic film is presented; the optimal signal resolution is determined, as a function of the noise level and the quantization step, in the digitization process of films and the useful optical density range is set, as a function of the required uncertainty level, for a densitometric system. Marginal distributions of portal images are similar to those of natural images. This also applies to the statistical relationships between wavelet coefficients, intra-band and inter-band. These facts result in a better

  12. A Science Portal and Archive for Extragalactic Globular Cluster Systems Data

    NASA Astrophysics Data System (ADS)

    Young, Michael; Rhode, Katherine L.; Gopu, Arvind

    2015-01-01

    For several years we have been carrying out a wide-field imaging survey of the globular cluster populations of a sample of giant spiral, S0, and elliptical galaxies with distances of ~10-30 Mpc. We use mosaic CCD cameras on the WIYN 3.5-m and Kitt Peak 4-m telescopes to acquire deep BVR imaging of each galaxy and then analyze the data to derive global properties of the globular cluster system. In addition to measuring the total numbers, specific frequencies, spatial distributions, and color distributions for the globular cluster populations, we have produced deep, high-quality images and lists of tens to thousands of globular cluster candidates for the ~40 galaxies included in the survey.With the survey nearing completion, we have been exploring how to efficiently disseminate not only the overall results, but also all of the relevant data products, to the astronomical community. Here we present our solution: a scientific portal and archive for extragalactic globular cluster systems data. With a modern and intuitive web interface built on the same framework as the WIYN One Degree Imager Portal, Pipeline, and Archive (ODI-PPA), our system will provide public access to the survey results and the final stacked mosaic images of the target galaxies. In addition, the astrometric and photometric data for thousands of identified globular cluster candidates, as well as for all point sources detected in each field, will be indexed and searchable. Where available, spectroscopic follow-up data will be paired with the candidates. Advanced imaging tools will enable users to overlay the cluster candidates and other sources on the mosaic images within the web interface, while metadata charting tools will allow users to rapidly and seamlessly plot the survey results for each galaxy and the data for hundreds of thousands of individual sources. Finally, we will appeal to other researchers with similar data products and work toward making our portal a central repository for data

  13. The SERC K12 Educators Portal to Teaching Activities and Pedagogic Approaches

    NASA Astrophysics Data System (ADS)

    Larsen, K.; Kirk, K. B.; Manduca, C. A.; Ledley, T. S.; Schmitt, L.

    2013-12-01

    The Science Education Resource Center (SERC) has created a portal to information for K12 educators to provide high-quality grade level appropriate materials from a wide variety of projects and topics. These materials were compiled across the SERC site, showcasing materials that were created for, or easily adaptable to, K12 classrooms. This resource will help support implementation of Next Generation Science Standards by assisting educators in finding innovative resources to address areas of instruction that are conceptually different than previous national and state science standards. Specifically, the K12 portal assists educators in learning about approaches that address the cross-cutting nature of science concepts, increasing students quantitative reasoning and numeracy skills, incorporating technology such as GIS in the classroom, and by assisting educators of all levels of K12 instruction in using relevant and meaningful ways to teach science concepts. The K12 portal supports educators by providing access to hundreds of teaching activities covering a wide array of science topics and grade levels many of which have been rigorously reviewed for pedagogic quality and scientific accuracy. The portal also provides access to web pages that enhance teaching practices that help increase student's system thinking skills, make lectures interactive, assist instructors in conducting safe and effective indoor and outdoor labs, providing support for teaching energy and climate literacy principles, assisting educators in addressing controversial content, provide guidance in engaging students affective domain, and provides a collection of tools for making teaching relevant in 21st century classrooms including using GIS, Google Earth, videos, visualizations and simulations to model and describe scientific concepts. The portal also provides access to material for specific content and audiences by (1) Supporting AGIs 'Map your World' week to specifically highlight teaching

  14. Accessing IceBridge Data Products - The OIB Portal

    NASA Astrophysics Data System (ADS)

    Tanner, S.; Oldenburg, J.; Collins, J. A.; Lewis, S.; Schaffer, F.

    2013-12-01

    NASA's Operation IceBridge mission both collects and makes available airborne remote sensing measurements over the polar regions to bridge the gap between NASA's Ice, Cloud and Land Elevation satellite (ICESat) mission and the upcoming ICESat-2 mission in 2016. The flight paths are carefully chosen areas of scientific interest, and the diverse set of instruments aboard each flight provide a more robust and thorough set of measurements than can satellite-based sensors. Instruments currently in use gather data on ice and snow thickness, bedrock topography, high-resolution photography, and other scientific properties. Shortly after collection, the data are transferred to the National Snow and Ice Data Center (NSIDC) for permanent storage and free, public access. At NSIDC, the data are organized with detailed metadata and made available through several avenues. The primary point of access for IceBridge data is the IceBridge Data Portal, located at http://nsidc.org/icebridge/portal/. This data portal allows users to both quickly find data that they seek or just peruse the available data holdings through the user interface. Ease of use is a top priority in the portal development to allow the user to concentrate on the science behind the data instead of how to navigate the website. Past development of the portal has focused on clarity of data presentation and access to the data itself. Current and planned development will see substantial additions to the filtering options, navigational tools, and visualization capabilities. Metadata are heavily relied upon to drive the data organization and access at NSIDC, particularly in the IceBridge Data Portal. The Portal's interactive maps of the polar regions allow users to search for data geographically. A user may also see how data at a specific location change over time using the Portal's temporal filters. In addition, the IceBridge flights themselves are searchable if a user is looking for data from a specific instrument

  15. Vascular corrosion casting: analyzing wall shear stress in the portal vein and vascular abnormalities in portal hypertensive and cirrhotic rodents.

    PubMed

    Van Steenkiste, Christophe; Trachet, Bram; Casteleyn, Christophe; van Loo, Denis; Van Hoorebeke, Luc; Segers, Patrick; Geerts, Anja; Van Vlierberghe, Hans; Colle, Isabelle

    2010-11-01

    Vascular corrosion casting is an established method of anatomical preparation that has recently been revived and has proven to be an excellent tool for detailed three-dimensional (3D) morphological examination of normal and pathological microcirculation. In addition, the geometry provided by vascular casts can be further used to calculate wall shear stress (WSS) in a vascular bed using computational techniques. In the first part of this study, the microvascular morphological changes associated with portal hypertension (PHT) and cirrhosis in vascular casts are described. The second part of this study consists of a quantitative analysis of the WSS in the portal vein in casts of different animal models of PHT and cirrhosis using computational fluid dynamics (CFD). Microvascular changes in the splanchnic, hepatic and pulmonary territory of portal hypertensive and cirrhotic mice are described in detail with stereomicroscopic examination and scanning electron microscopy. To our knowledge, our results are the first to report the vascular changes in the common bile duct ligation cirrhotic model. Calculating WSS using CFD methods is a feasible technique in PHT and cirrhosis, enabling the differentiation between different animal models. First, a dimensional analysis was performed, followed by a CFD calculation describing the spatial and temporal WSS distributions in the portal vein. WSS was significantly different between sham/cirrhotic/pure PHT animals with the highest values in the latter. Up till now, no techniques have been developed to quantify WSS in the portal vein in laboratory animals. This study showed for the first time that vascular casting has an important role not only in the morphological evaluation of animal models of PHT and cirrhosis, but also in defining the biological response of the portal vein wall to hemodynamic changes. CFD in 3D geometries can be used to describe the spatial and temporal variations in WSS in the portal vein and to better understand

  16. Earth Science Data Records Sharing Supported by the MEaSUREs Spatial Web Portal

    NASA Astrophysics Data System (ADS)

    Miao, L.; Houser, P.; Yang, C.; Wu, H.

    2009-12-01

    In past few decades NASA has launched many satellites and deployed many sensors to provide three-dimensional profiles of Earth’s atmosphere and surface. These are part of sophisticated observation systems that incorporate in-situ, satellite, model output, and other technologies, that have resulted in high quality, long-term earth science data records. However, there currently exists no systematic effort to make these integrated datasets usable in earth science research environments. So, we will leverage our extensive experience with emerging technologies developed around GrADS (Grid Analysis and Display System),GDS (GrADS Data Server) and OPeNDAP (The Open-source Project for a Network Data Access Protocol) to develop a Spatial Web Portal (SWP) for the terrestrial water cycle MEaSUREs project to provide distributed data access, distributed data analysis and integrated data display. In this study, three parts are investigated on how to share ESDRs (Earth Science Data Records) by MEaSUREs SWP including a) establishing a publicly-accessible ESDR data portal, b) developing an on-line meta-database to enable quick discovery of relevant ESDR resources based on CSW 2.0.2 (Catalog Service for the Web), c) using intelligent, web-enabled services that simplifies data access, processing and exchange to distribute ESDRs by handling HDF, netCDF, GRIB or binary data formats.

  17. Arthroscopic all-inside lateral meniscus suture using posterolateral portal.

    PubMed

    Ahn, Jin Hwan; Oh, Irvin

    2006-05-01

    A new arthroscopic all-inside suture for lateral meniscus posterior horn tear using a single posterolateral portal is described. A lateral meniscus posterior horn peripheral longitudinal tear is often seen with anterior cruciate ligament injury or discoid lateral meniscus tear. Conventional repair methods, such as arthroscopic inside-out, outside-in, or all-inside sutures, can be cumbersome and technically demanding. Our all-inside suture using the posterolateral portal allows thorough visualization of the posterolateral structures, excellent coaptation of torn meniscus, strong knot tightening, and avoidance of inadvertent cartilage injury. The arthroscope is inserted through the anteromedial portal and reaches the posterolateral compartment by a transcondylar approach. A suture hook is introduced into the posterolateral portal without a cannula, penetrates posterior peripheral rim, crosses the tear, and passes through mobile torn fragment. A large amount of No. 0 PDS is passed, so that it curls up inside the joint. After the suture hook is removed, a suture retriever is inserted through the posterolateral portal to pull out 2 ends of the PDS at the same time. The retrieved suture ends are passed through a knot pusher and a 5.5-mm cannula is introduced over the retrieved suture materials for the SMC knot to be tied. A longitudinal tear of lateral meniscus posterior horn is repaired with 2 to 3 sutures. PMID:16651176

  18. Portal hypertensive biliopathy: A single center experience and literature review.

    PubMed

    Suárez, Vanessa; Puerta, Andrés; Santos, Luisa Fernanda; Pérez, Juan Manuel; Varón, Adriana; Botero, Rafael Claudino

    2013-03-27

    Portal hypertensive biliopathy (PHB) is characterized by anatomical and functional abnormalities of the intrahepatic, extrahepatic and pancreatic ducts, in patients with portal hypertension associated to extrahepatic portal vein obstruction and less frequently to cirrhosis. These morphological changes, consisting in dilatation and stenosis of the biliary tree, are due to extensive venous collaterals occurring in an attempt to decompress the portal venous blockage. It is usually asymptomatic until it progresses to more advanced stages with cholestasis, jaundice, biliary sludge, gallstones, cholangitis and finally biliary cirrhosis. Imaging modalities of the biliary tree such as Doppler ultrasound, computed tomography, magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography are essential to establish the diagnosis and the need of therapeutical interventions. Once the diagnosis is established, treatment with ursodesoxycholic acid seems to be beneficial. Decompression of the biliary tree to dilate, remove stones or implant biliary prosthesis by endoscopic or surgical procedures (hepato-yeyunostomy) usually resolves the cholestatic picture and prevents septic complications. The ideal treatment is the decompression of the portal system, with transjugular intrahepatic porto-systemic shunt or a surgical porto-systemic shunt. Unfortunately, few patients will be candidates for these procedures due to the extension of the thrombotic process. The purpose of this paper is to report the first 3 cases of PHB seen in a Colombian center and to review the literature. PMID:23556047

  19. Single-Portal Arthroscopy: Report of a New Technique

    PubMed Central

    Cooper, Daniel E.; Fouts, Brian

    2013-01-01

    A new technique of single-portal arthroscopy using new instrumentation for arthroscopic knee surgery is reported. The procedure is intended for “targeted” surgery to address limited pathology. The arthroscope, cutters, and biters are all introduced into the joint through 1 portal. The technique is generally applicable to knee arthroscopy for isolated conditions and potentially useful in treating other joints. A 2.9-mm-diameter, light-sensitive, high-definition, 20-cm-long arthroscope is inserted through a 4.6-mm cannula. This arthroscope-cannula combination yields fluid flow mechanics similar to a standard 4-mm arthroscope in a 5.8-mm cannula. A Parallel Portal Cannula (PPC) (Stryker Endoscopy) is applied to the arthroscope cannula, producing a “double-barrel” system for entry into the joint. The PPC allows for sliding and rotational freedom along the axis of the arthroscope cannula but also locks in place once a desired position is achieved. PPC devices are available in zero-length, short (25-mm), and long (55-mm) sizes. Cutters that are bent in the mid shaft are available in 3.5- and 4-mm diameters. The instrumentation system allows both viewing with the arthroscope and passage of working cutters and biters through a single 9- to 10-mm portal. Potential advantages of single-portal arthroscopy include decreased patient morbidity and recovery time while still allowing for adequate treatment of limited knee pathology. PMID:24265996

  20. CzechGeo/EPOS - Building a national data portal

    NASA Astrophysics Data System (ADS)

    Zednik, J.; Hejda, P.

    2012-04-01

    CzechGeo/EPOS is the consortium of seven geoscience institutions in the Czech Republic (Institute of Geophysics AS CR Prague, Institute of Rock Structure and Mechanics AS CR Prague, Institute of Geonics AS CR Ostrava, Institute of Physics of the Earth, Masaryk University Brno, Faculty of Mathematics and Physics, Charles University Prague, Faculty of Science, Charles University Prague, and Research Institute of Geodesy, Cartography and Topography Zdiby). These institutions operate a distributed system of seismic, GPS, magnetic, gravimetric and geodynamic observatories. The operational and personal costs of CzechGeo/EPOS are mostly covered by the Ministry of education, sports and youth within the support of twelve large research infrastructures in the Czech Republic. Web pages of the project www.czechgeo.cz are being built as a data portal which should integrate all the data and services provided by the involved institutions and research infrastructures. Seismic portal offers selected portions of digital data from permanent, local and temporary seismic stations, locations of seismic events in the country and worldwide, daily seismograms from permanent observatories and local seismic network Webnet, seismic bulletins and catalogs, and macroseismic observations on the territory of the Czech Republic. Magnetic portal involves besides real-time magnetograms also recent state of geomagnetic activity and its forecast for the next day. GPS portal will provide preprocessed data from regional GPS stations. Building the national portal is closely related with the development of the Preparatory phase of the EPOS (European Plate Observing System) project.

  1. Patient Portal Integration - A Native IHE Connector Implementation for PEHR.

    PubMed

    Yüksekogul, Nilay; Schreiweis, Björn; Weiss, Nicolas; Aguduri, Lakshmi S; Brandner, Antje; Bronsch, Tobias; Pensold, Peter; Stein, Katharina E; Helmer, Axel; Bergh, Björn; Heinze, Oliver

    2016-01-01

    Providing patients with access to their medical data has recently evolved as a topic in several countries. Different approaches are possible. For example patient portals are used for patient access towards medical data. The University Hospital Heidelberg is engaged in a research project to develop a personal cross-enterprise electronic health record (PEHR). The objective of this work is to describe the architecture and implementation of a component called IHE Connector which represents the native IHE-based integration between the patient portal and the PEHR core components. The architecture of the PEHR is accepted based on international standards. The core components consist out of ready to use software products like a master patient index. The patient portal has been developed using Liferay framework. The IHE Connector is mainly based on the Open eHealth Integration Platform (IPF) Framework, which has been deeply integrated into the patient portal to support the needed IHE transactions. Several IHE profiles for sharing documents and patient information are supported by the IHE Connector. As IPF already provides interfaces for some IHE profiles others had to be developed from scratch. The IHE Connector can not only be used for connectivity between patient portal and PEHR core, but also provide connectivity for third party apps and healthcare providers' information systems. PMID:27577365

  2. Generic XML-based framework for metadata portals

    NASA Astrophysics Data System (ADS)

    Schindler, Uwe; Diepenbroek, Michael

    2008-12-01

    We present a generic and flexible framework for building geoscientific metadata portals independent of content standards for metadata and protocols. Data can be harvested with commonly used protocols (e.g., Open Archives Initiative Protocol for Metadata Harvesting) and metadata standards like DIF or ISO 19115. The new Java-based portal software supports any XML encoding and makes metadata searchable through Apache Lucene. Software administrators are free to define searchable fields independent of their type using XPath. In addition, by extending the full-text search engine (FTS) Apache Lucene, we have significantly improved queries for numerical and date/time ranges by supplying a new trie-based algorithm, thus, enabling high-performance space/time retrievals in FTS-based geo portals. The harvested metadata are stored in separate indexes, which makes it possible to combine these into different portals. The portal-specific Java API and web service interface is highly flexible and supports custom front-ends for users, provides automatic query completion (AJAX), and dynamic visualization with conventional mapping tools. The software has been made freely available through the open source concept.

  3. Laparoscopic Cholecystectomy in Patients with Bilharzial Portal Hypertension

    PubMed Central

    Ismail, Abu Azab; Mohamed, Ibnoaf; Suliman, Fedail S

    2000-01-01

    Objective: The purpose of this study was to evaluate the results of laparoscopic cholecystectomy in patients with bilharzial portal hypertension. Methods: Patients who had gallstones and bilharzia had ultrasonographic assessment of peri-portal fibrosis, endoscopy, hemagglutination and rectal snip. Operating time, blood loss, hospital stay, time of return to work and operative mortality were recorded. Follow-up was two weeks, six weeks and six months after discharge. Results: Twenty-five out of 450 patients, who had laparoscopic cholecystectomy, suffered from bilharzial portal hypertension. Ten patients had grade 1 varices, 10 had grade 2 varices, and 5 had grade 3 esophageal varices. All patients had varying degrees of peri-portal fibrosis as shown by ultrasound. Rectal snip showed schistosoma mansoni in 5 patients, and a hemagglutination test was positive in all. Two patients had conversion to open cholecystectomy. Mean operating time was 1 hour and 15 minutes. Average blood loss was 50 cc. Mean hospital stay for 23 patients was 48 hours. Average time of return to work was 2 weeks in 23 patients and 6 weeks in the 2 patients who had conversion. Twenty-two patients benefited from the operation. There was no mortality in this series. Conclusions: Laparoscopic cholecystectomy in patients with bilharzial portal hypertension is feasible and has low morbidity. PMID:10917123

  4. Algorithms for contrast enhancement of electronic portal images

    NASA Astrophysics Data System (ADS)

    Díez, S.; Sánchez, S.

    2015-11-01

    An implementation of two new automatized image processing algorithms for contrast enhancement of portal images is presented as suitable tools which facilitate the setup verification and visualization of patients during radiotherapy treatments. In the first algorithm, called Automatic Segmentation and Histogram Stretching (ASHS), the portal image is automatically segmented in two sub-images delimited by the conformed treatment beam: one image consisting of the imaged patient obtained directly from the radiation treatment field, and the second one is composed of the imaged patient outside it. By segmenting the original image, a histogram stretching can be independently performed and improved in both regions. The second algorithm involves a two-step process. In the first step, a Normalization to Local Mean (NLM), an inverse restoration filter is applied by dividing pixel by pixel a portal image by its blurred version. In the second step, named Lineally Combined Local Histogram Equalization (LCLHE), the contrast of the original image is strongly improved by a Local Contrast Enhancement (LCE) algorithm, revealing the anatomical structures of patients. The output image is lineally combined with a portal image of the patient. Finally the output images of the previous algorithms (NLM and LCLHE) are lineally combined, once again, in order to obtain a contrast enhanced image. These two algorithms have been tested on several portal images with great results.

  5. Evolution of portal hypertension and mechanisms involved in its maintenance in a rat model

    SciTech Connect

    Sikuler, E.; Kravetz, D.; Groszmann, R.J.

    1985-06-01

    In rats with portal hypertension induced by partial ligation of the portal vein, the authors have recently demonstrated an increased portal venous inflow that becomes an important factor in the maintenance of portal hypertension. The sequence of events that leads into this circulatory disarray is unknown. The authors evaluated chronologically the chain of hemodynamic changes that occurred after portal hypertension was induced by partial ligation of the portal vein. In this model it is possible to follow, from the initiation of the portal-hypertensive state, the interaction between blood flow and resistance in the portal system as well as the relation between the development of portal-systemic shunting and the elevated portal venous inflow. The study was performed in 45 portal-hypertensive rats and in 29 sham-operated rats. Blood flow and portal-systemic shunting were measured by radioactive microsphere techniques. The constriction of the portal vein was immediately followed by a resistance-induced portal hypertension characterized by increased portal resistance (9.78 +/- 0.89 vs. 4.18 +/- 0.71 dyn X s X cm-5 X 10(4), mean +/- SE, P less than 0.01), increased portal pressure (17.7 +/- 0.9 vs. 9.5 +/- 0.6 mmHg, P less than 0.001), and decreased portal venous inflow (3.93 +/- 0.26 vs. 6.82 +/- 0.49 ml X min-1 X 100 g body wt-1, P less than 0.001).

  6. Hepatocellular Carcinoma Invading the Main Portal Vein: Treatment with Transcatheter Arterial Chemoembolization and Portal Vein Stenting

    SciTech Connect

    Zhang Xuebin Wang Jianhua Yan Zhiping Qian Sheng Liu Rong

    2009-01-15

    To retrospectively analyze the therapeutic results of percutaneous transhepatic portal vein stenting (PTPVS) and transcatheter arterial chemoembolization (TACE) treatment in 58 patients with hepatocellular carcinoma (HCC) invading the main portal vein (MPV). A total of 58 procedures of PTPVS were performed, immediately after which TACE was undertaken to control HCC. The clinical effects, complications, digital subtraction angiographic appearance, stent patency rates, cumulative survival rates, and predictive factors for survival were evaluated. The Kaplan-Meyer method and the log rank test were used for survival analysis. Multivariable analysis was also conducted by the Cox proportional hazard model. No patient died during stent placement or within the first 24 h. No severe procedure-related complications were observed. After stent placement, the mean {+-} standard deviation portal venous pressure levels decreased from 41.43 {+-} 8.56 cmH{sub 2}O to 37.19 {+-} 7.89 cmH{sub 2}O (p < 0.01). At the time of analysis, 9 of the 58 patients survived. The 60-, 180-, 360-, and 720-day cumulative patency rates were 98.1%, 71.0%, 52.6%, and 42.1%, respectively, with a mean patency time of 552.9 {+-} 88.2 days and a median patency time of 639.00 {+-} 310.00 (95% confidence interval [95% CI], 31.40-1246.60) days. The 60-, 180-, 360-, and 720-day cumulative survival rates for the total study population were 74.1%, 27.1%, 17.2%, and 13.8%, respectively, with a median survival time of 113 {+-} 27.29 (95% CI, 59.51-166.49) days. In the univariate analysis, the following six variables were significantly associated with the prognosis: (1) HCC type; (2) Child-Pugh grade; (3) MPV stenosis/occlusion; (4) arteriovenous shunt; (5) iodized oil deposition; and (6) number of TACE procedure. In addition, having diffuse-type HCC and Child-Pugh grade B disease were each independent factors associated with decreased survival time in the multivariate analysis. PTPVS-TACE is feasible and may be

  7. Spectroscopic enhancement in nanoparticles embedded glasses

    NASA Astrophysics Data System (ADS)

    Sahar, M. R.; Ghoshal, S. K.

    2014-09-01

    This presentation provides an overview of the recent progress in the enhancement of the spectroscopic characteristics of the glass embedded with nanoparticles (NPs). Some of our research activities with few significantly new results are highlighted and facilely analyzed. The science and technology dealing with the manipulation of the physical properties of rare earth doped inorganic glasses by embedding metallic NPs or nanoclusters produce the so-called 'nanoglass'. Meanwhile, the spectroscopic enhancement relates the intensity of the luminescence measured at certain transition. The enhancement which expectedly due to the 'plasmonics wave' (referring to the coherent coupling of photons to free electron oscillations called plasmon) occurs at the interface between a conductor and a dielectric. Plasmonics being an emerging concept in advanced optical material of nanophotonics has given this material the ability to exploit the optical response at nanoscale and opened up a new avenue in metal-based glass optics. There is a vast array of plasmonic NPs concepts yet to be explored, with applications spanning solar cells, (bio) sensing, communications, lasers, solid-state lighting, waveguides, imaging, optical data transfer, display and even bio-medicine. Localized surface plasmon resonance (LSPR) can enhance the optical response of nanoglass by orders of magnitude as observed. The luminescence enhancement and surface enhanced Raman scattering (SERS) are new paradigm of research. The enhancement of luminescence due to the influence of metallic NPs is the recurring theme of this paper.

  8. Spectroscopic enhancement in nanoparticles embedded glasses

    SciTech Connect

    Sahar, M. R. Ghoshal, S. K.

    2014-09-25

    This presentation provides an overview of the recent progress in the enhancement of the spectroscopic characteristics of the glass embedded with nanoparticles (NPs). Some of our research activities with few significantly new results are highlighted and facilely analyzed. The science and technology dealing with the manipulation of the physical properties of rare earth doped inorganic glasses by embedding metallic NPs or nanoclusters produce the so-called 'nanoglass'. Meanwhile, the spectroscopic enhancement relates the intensity of the luminescence measured at certain transition. The enhancement which expectedly due to the 'plasmonics wave' (referring to the coherent coupling of photons to free electron oscillations called plasmon) occurs at the interface between a conductor and a dielectric. Plasmonics being an emerging concept in advanced optical material of nanophotonics has given this material the ability to exploit the optical response at nanoscale and opened up a new avenue in metal-based glass optics. There is a vast array of plasmonic NPs concepts yet to be explored, with applications spanning solar cells, (bio) sensing, communications, lasers, solid-state lighting, waveguides, imaging, optical data transfer, display and even bio-medicine. Localized surface plasmon resonance (LSPR) can enhance the optical response of nanoglass by orders of magnitude as observed. The luminescence enhancement and surface enhanced Raman scattering (SERS) are new paradigm of research. The enhancement of luminescence due to the influence of metallic NPs is the recurring theme of this paper.

  9. Spectroscopic characterization of nitroaromatic landmine signature explosives

    NASA Astrophysics Data System (ADS)

    Hernandez-Rivera, Samuel P.; Manrique-Bastidas, Cesar A.; Blanco, Alejandro; Primera, Oliva M.; Pacheco, Leonardo C.; Castillo-Chara, Jairo; Castro, Miguel E.; Mina, Nairmen

    2004-09-01

    TNT and DNT are important explosives used as base charges of landmines and other explosive devices. They are often combined with RDX in specific explosive formulations. Their detection in vapor phase as well as in soil in contact with the explosives is important in landmine detection technology. The spectroscopic signatures of nitroaromatic compounds in neat forms: crystals, droplets, and recrystallized samples were determined by Raman Microspectroscopy (RS), Fourier Transform Infrared Microscopy (FTIR) and Fiber Optics Coupled - Fourier Transform Infrared Spectroscopy (FOC-FTIR) using a grazing angle (GA) probe. TNT exhibits a series of characteristic bands: vibrational signatures, which allow its detection in soil. The spectroscopic signature of neat TNT is dominated by strong bands about 1380 and 2970 cm-1. The intensity and position of these bands were found remarkably different in soil samples spiked with TNT. The 1380 cm-1 band is split into a number of bands in that region. The 2970 cm-1 band is reduced in intensity and new bands are observed about 2880 cm-1. The results are consistent with a different chemical environment of TNT in soil as compared to neat TNT. Interactions were found to be dependent on the physical source of the explosive. In the case of DNT-sand interactions, shifts in vibrational frequencies of the explosives as well as the substrates were found.

  10. A DVD Spectroscope: A Simple, High-Resolution Classroom Spectroscope

    ERIC Educational Resources Information Center

    Wakabayashi, Fumitaka; Hamada, Kiyohito

    2006-01-01

    Digital versatile disks (DVDs) have successfully made up an inexpensive but high-resolution spectroscope suitable for classroom experiments that can easily be made with common material and gives clear and fine spectra of various light sources and colored material. The observed spectra can be photographed with a digital camera, and such images can…

  11. Special Nuclear Material Portal Monitoring at the Nevada Test Site

    SciTech Connect

    DeAnn Long; Michael Murphy

    2008-07-01

    Prior to April 2007, acceptance and performance testing of the various Special Nuclear Material (SNM) monitoring devices at the Nevada Test Site (NTS) was performed by the Radiological Health Instrumentation department. Calibration and performance testing on the PM-700 personnel portal monitor was performed, but there was no test program for the VM-250 vehicle portal monitor. The handheld SNM monitors, the TSA model 470B, were being calibrated annually, but there was no performance test program. In April of 2007, the Material Control and Accountability Manager volunteered to take over performance testing of all SNM portal monitors at NTS in order to strengthen the program and meet U.S. Department of Energy Order requirements. This paper will discuss the following activities associated with developing a performance testing program: changing the culture, learning the systems, developing and implementing procedures, troubleshooting and repair, validating the process, physical control of equipment, acquisition of new systems, and implementing the performance test program.

  12. CPTAC Assay Portal: a repository of targeted proteomic assays

    SciTech Connect

    Whiteaker, Jeffrey R.; Halusa, Goran; Hoofnagle, Andrew N.; Sharma, Vagisha; MacLean, Brendan; Yan, Ping; Wrobel, John; Kennedy, Jacob; Mani, DR; Zimmerman, Lisa J.; Meyer, Matthew R.; Mesri, Mehdi; Rodriguez, Henry; Abbateillo, Susan E.; Boja, Emily; Carr, Steven A.; Chan, Daniel W.; Chen, Xian; Chen, Jing; Davies, Sherri; Ellis, Matthew; Fenyo, David; Hiltket, Tara; Ketchum, Karen; Kinsinger, Christopher; Kuhn, Eric; Liebler, Daniel; Lin, De; Liu, Tao; Loss, Michael; MacCoss, Michael; Qian, Weijun; Rivers, Robert; Rodland, Karin D.; Ruggles, Kelly; Scott, Mitchell; Smith, Richard D.; Thomas, Stefani N.; Townsend, Reid; Whiteley, Gordon; Wu, Chaochao; Zhang, Hui; Zhang, Zhen; Paulovich, Amanda G.

    2014-06-27

    To address these issues, the Clinical Proteomic Tumor Analysis Consortium (CPTAC) of the National Cancer Institute (NCI) has launched an Assay Portal (http://assays.cancer.gov) to serve as a public repository of well-characterized quantitative, MS-based, targeted proteomic assays. The purpose of the CPTAC Assay Portal is to facilitate widespread adoption of targeted MS assays by disseminating SOPs, reagents, and assay characterization data for highly characterized assays. A primary aim of the NCI-supported portal is to bring together clinicians or biologists and analytical chemists to answer hypothesis-driven questions using targeted, MS-based assays. Assay content is easily accessed through queries and filters, enabling investigators to find assays to proteins relevant to their areas of interest. Detailed characterization data are available for each assay, enabling researchers to evaluate assay performance prior to launching the assay in their own laboratory.

  13. Probing the fermionic Higgs portal at lepton colliders

    NASA Astrophysics Data System (ADS)

    Fedderke, Michael A.; Lin, Tongyan; Wang, Lian-Tao

    2016-04-01

    We study the sensitivity of future electron-positron colliders to UV completions of the fermionic Higgs portal operator {H}^{dagger }{H}_{overline{χ}χ } . Measurements of precision electroweak S and T parameters and the e + e - → Zh cross-section at the CEPC, FCC-ee, and ILC are considered. The scalar completion of the fermionic Higgs portal is closely related to the scalar Higgs portal, and we summarize existing results. We devote the bulk of our analysis to a singlet-doublet fermion completion. Assuming the doublet is sufficiently heavy, we construct the effective field theory (EFT) at dimension-6 in order to compute contributions to the observables. We also provide full one-loop results for S and T in the general mass parameter space. In both completions, future precision measurements can probe the new states at the (multi-)TeV scale, beyond the direct reach of the LHC.

  14. Bilateral Emphysematous Pyelonephritis with Hepatic Portal Venous Gas: Case Report.

    PubMed

    Cheng, Mao Li; Nording, Hasnizal; Lim, Chen Hong

    2015-01-01

    Emphysematous pyelonephritis is a rare life-threatening condition caused by a severe acute necrotising infection of the renal parenchyma and its perinephric tissues, and it is commonly seen in diabetic patients. There is a rare association between emphysematous pyelonephritis and hepatic portal venous gas. Hepatic portal venous gas is an uncommon radiological finding, which implies a significant underlying abdominal disease. The management of emphysematous pyelonephritis has evolved from prompt nephrectomy to medical therapy. In the present report, we present a case of a diabetic woman diagnosed with bilateral emphysematous pyelonephritis with hepatic portal venous gas that was successfully managed medically despite the presence of poor prognostic factors, such as acute renal failure and thrombocytopenia. PMID:26715900

  15. Non-linear Higgs portal to Dark Matter

    NASA Astrophysics Data System (ADS)

    Brivio, I.; Gavela, M. B.; Merlo, L.; Mimasu, K.; No, J. M.; del Rey, R.; Sanz, V.

    2016-04-01

    The Higgs portal to scalar Dark Matter is considered in the context of non-linearly realised electroweak symmetry breaking. We determine the dominant interactions of gauge bosons and the physical Higgs particle h to a scalar singlet Dark Matter candidate. Phenomenological consequences are also studied in detail, including the possibility of distinguishing this scenario from the standard Higgs portal in which the electroweak symmetry breaking is linearly realised. Two features of significant impact are: i) the connection between the electroweak scale v and the Higgs particle departs from the ( v + h) functional dependence, as the Higgs field is not necessarily an exact electroweak doublet; ii) the presence of specific couplings that arise at different order in the non-linear and in the linear expansions. These facts deeply affect the Dark Matter relic abundance, as well as the expected signals in direct and indirect searches and collider phenomenology, where Dark Matter production rates are enhanced with respect to the standard portal.

  16. Structure-centered portal for child psychiatry research

    PubMed Central

    Rane, Pallavi; Haselgrove, Christian; Hodge, Steven M.; Frazier, Jean A.; Kennedy, David N.

    2014-01-01

    The real world needs of the clinical community require a domain-specific solution to integrate disparate information available from various web-based resources for data, materials, and tools into routine clinical and clinical research setting. We present a child-psychiatry oriented portal as an effort to deliver a knowledge environment wrapper that provides organization and integration of multiple information and data sources. Organized semantically by resource context, the portal groups information sources by context type, and permits the user to interactively “narrow” or “broaden” the scope of the information resources that are available and relevant to the specific context. The overall objective of the portal is to bring information from multiple complex resources into a simple single uniform framework and present it to the user in a single window format. PMID:24817850

  17. Galaxy Portal: interacting with the galaxy platform through mobile devices

    PubMed Central

    Børnich, Claus; Grytten, Ivar; Hovig, Eivind; Paulsen, Jonas; Čech, Martin; Sandve, Geir Kjetil

    2016-01-01

    Summary: We present Galaxy Portal app, an open source interface to the Galaxy system through smart phones and tablets. The Galaxy Portal provides convenient and efficient monitoring of job completion, as well as opportunities for inspection of results and execution history. In addition to being useful to the Galaxy community, we believe that the app also exemplifies a useful way of exploiting mobile interfaces for research/high-performance computing resources in general. Availability and implementation: The source is freely available under a GPL license on GitHub, along with user documentation and pre-compiled binaries and instructions for several platforms: https://github.com/Tarostar/QMLGalaxyPortal. It is available for iOS version 7 (and newer) through the Apple App Store, and for Android through Google Play for version 4.1 (API 16) or newer. Contact: geirksa@ifi.uio.no PMID:26819474

  18. Portals 4 network API definition and performance measurement

    SciTech Connect

    Brightwell, R. B.

    2012-03-01

    Portals is a low-level network programming interface for distributed memory massively parallel computing systems designed by Sandia, UNM, and Intel. Portals has been designed to provide high message rates and to provide the flexibility to support a variety of higher-level communication paradigms. This project developed and analyzed an implementation of Portals using shared memory in order to measure and understand the impact of using general-purpose compute cores to handle network protocol processing functions. The goal of this study was to evaluate an approach to high-performance networking software design and hardware support that would enable important DOE modeling and simulation applications to perform well and to provide valuable input to Intel so they can make informed decisions about future network software and hardware products that impact DOE applications.

  19. AVISO+, the new reference web portal for altimetry

    NASA Astrophysics Data System (ADS)

    Rosmorduc, Vinca; Bronner, Emilie; Guinle, Thierry; Maheu, Caroline; Morrow, Rosemary; Nino, Fernando; Birol, Florence

    2014-05-01

    AVISO is the showcase of CNES activities in altimetry. Indeed, the altimetric products processed by the SALP service from CNES (Service d'Altimetrie et de Localisation Precise) are disseminated via AVISO portal since 1995. In recent years, AVISO became a reference in the international oceanographic and altimetry communities, with more than 5,000 registered users in 2013. In 2014 AVISO is enlarging its applications outside the purely ocean-oriented ones, thus becoming AVISO + (www.aviso.altimetry.fr). The portal opens to new applications such as hydrology / coastal / ice. Moreover, it merges with the CTOH (French Observation Service dedicated to satellite altimetry studies) website to provide users with operational as well as demonstration products and expertise in a unique website. We present here all the novelties - new look, new functionnalities, new products, new data access service… hoping to see you soon on our brand-new altimetry portal, www.aviso.altimetry.fr!

  20. Portacaval graft patency demonstrated by scintigraphic calculation of portal contribution to hepatic blood flow.

    PubMed

    Martín-Comín, J; Segarra, M I; Pujol, J; Mairal, L; Sans, L; Mora, J; Puchal, R

    1992-11-01

    The case presented refers to a cirrhotic patient with portal hypertension in whom a portacaval graft bypass was surgically implanted. The calculation of the portal contribution to hepatic blood flow helped to demonstrate the patency of the graft. PMID:1424378

  1. Website Babies Portal: development and evaluation of the contents regarding orofacial functions

    PubMed Central

    CORRÊA, Camila de Castro; PAULETO, Adriana Regina Colombo; FERRARI, Deborah Viviane; BERRETIN-FELIX, Giédre

    2013-01-01

    Education mediated by technology facilitates the access to information and can reach more people, including a broader range of socio-economic groups and ages, and at a low-cost. The website "Babies Portal - Speech-Language Pathology/Audiology and Dentistry" (http://portaldosbebes.fob.usp.br) was developed to provide parents with information on communication procedure disorders and oral health, enabling them to prevent and identify any changes in development early while looking for the best treatment. Objective: The objective is to describe the development and evaluation of the content pertaining to the oral functions featured in the "Babies Portal". Methods: The first stage consisted of a literature review, development/selection of illustrations and an evaluation of the possible external links that could be available. In the second stage, 10 speech-language and hearing pathologists (group A) and five parents of babies (group B) evaluated the website via an online form, which included ethical and personal information and questions about the quality, technical information and comparative prior knowledge acquired after the access. In the first stage, there was the construction of five sections ("The Oral Functions", "Breastfeeding", "Food", "Pacifier, baby bottle and finger sucking" and "Breath") based on scientific studies, presenting objective information, content links prepared by the Ministry of Health and a Dentistry section in the "Babies Portal" website. Videos, static and dynamic images were also distributed throughout the sections. Results: Regarding the second stage, 90% of all speech-language and hearing pathologists judged a good/excellent quality for all sections and classified the technical quality as very good. By their turn, 88% of the parents (group B) reported that the website helped or helped very much in understanding the contents, and 80% rated the quality as good or excellent. Conclusions: Five sections concerning the oral functions were

  2. Interactive web-based portals to improve patient navigation and connect patients with primary care and specialty services in underserved communities.

    PubMed

    Highfield, Linda; Ottenweller, Cecelia; Pfanz, Andre; Hanks, Jeanne

    2014-01-01

    This article presents a case study in the redesign, development, and implementation of a web-based healthcare clinic search tool for virtual patient navigation in underserved populations in Texas. It describes the workflow, assessment of system requirements, and design and implementation of two online portals: Project Safety Net and the Breast Health Portal. The primary focus of the study was to demonstrate the use of health information technology for the purpose of bridging the gap between underserved populations and access to healthcare. A combination of interviews and focus groups was used to guide the development process. Interviewees were asked a series of questions about usage, usability, and desired features of the new system. The redeveloped system offers a multitier architecture consisting of data, business, and presentation layers. The technology used in the new portals include Microsoft .NET Framework 3.5, Microsoft SQL Server 2008, Google Maps JavaScript API v3, jQuery, Telerik RadControls (ASP.NET AJAX), and HTML. The redesigned portals have 548 registered clinics, and they have averaged 355 visits per month since their launch in late 2011, with the average user visiting five pages per visit. Usage has remained relatively constant over time, with an average of 142 new users (40 percent) each month. This study demonstrates the successful application of health information technology to improve access to healthcare and the successful adoption of the technology by targeted end users. The portals described in this study could be replicated by health information specialists in other areas of the United States to address disparities in healthcare access. PMID:24808806

  3. Interactive Web-based Portals to Improve Patient Navigation and Connect Patients with Primary Care and Specialty Services in Underserved Communities

    PubMed Central

    Highfield, Linda; Ottenweller, Cecelia; Pfanz, Andre; Hanks, Jeanne

    2014-01-01

    This article presents a case study in the redesign, development, and implementation of a web-based healthcare clinic search tool for virtual patient navigation in underserved populations in Texas. It describes the workflow, assessment of system requirements, and design and implementation of two online portals: Project Safety Net and the Breast Health Portal. The primary focus of the study was to demonstrate the use of health information technology for the purpose of bridging the gap between underserved populations and access to healthcare. A combination of interviews and focus groups was used to guide the development process. Interviewees were asked a series of questions about usage, usability, and desired features of the new system. The redeveloped system offers a multitier architecture consisting of data, business, and presentation layers. The technology used in the new portals include Microsoft .NET Framework 3.5, Microsoft SQL Server 2008, Google Maps JavaScript API v3, jQuery, Telerik RadControls (ASP.NET AJAX), and HTML. The redesigned portals have 548 registered clinics, and they have averaged 355 visits per month since their launch in late 2011, with the average user visiting five pages per visit. Usage has remained relatively constant over time, with an average of 142 new users (40 percent) each month. This study demonstrates the successful application of health information technology to improve access to healthcare and the successful adoption of the technology by targeted end users. The portals described in this study could be replicated by health information specialists in other areas of the United States to address disparities in healthcare access. PMID:24808806

  4. Integrating Thematic Web Portal Capabilities into the NASA Earthdata Web Infrastructure

    NASA Technical Reports Server (NTRS)

    Wong, Minnie; Baynes, Kathleen E.; Huang, Thomas; McLaughlin, Brett

    2015-01-01

    This poster will present the process of integrating thematic web portal capabilities into the NASA Earth data web infrastructure, with examples from the Sea Level Change Portal. The Sea Level Change Portal will be a source of current NASA research, data and information regarding sea level change. The portal will provide sea level change information through articles, graphics, videos and animations, an interactive tool to view and access sea level change data and a dashboard showing sea level change indicators.

  5. Drug company's consumer health portal encourages return visits.

    PubMed

    2004-07-01

    How do you get consumers to return to your site? For some health-site surfers, the offer of a portal where they can customize pages and store their own data may have so much appeal that they'll make it their home on the Web. But to really win their loyalty, a consumer portal has to offer a lot of features that will help them manage their health activities. A good example is My Health Zone, launched by pharmaceutical company Schering-Plough. PMID:15346971

  6. [Non-cirrhotic portal hypertension with nearly lethal consequences].

    PubMed

    Börner, Nele; Korte, Wolfgang; Doenecke, Christian; Pfister, Maurus; Meyenberger, Christa; Semela, David; Sawatzki, Mikael

    2013-05-22

    We describe the case of a 48-year-old patient presenting with abdominal pain with a history of cerebral ischemia due to a patent foramen ovale with heterozygous factor V mutation. Initial work-up demonstrate a significant thrombosis of the portal venous system combined with signs of portal hypertension (ascites, oesophageal varices). Ultrasound reveals no signs of cirrhosis of the liver. Finally a JAK2 mutation can be detected. Prevention of oesophageal varices is refused. Finally a massive haemorrhage occured. PMID:23692908

  7. 2. West portal of Tunnel 22, view to the northwest, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. West portal of Tunnel 22, view to the northwest, 135mm lens. Note the use of concrete face and wingwalls, with dressed stone voussoirs, wingwall coping, concrete parapet with stone belt course and coping, and rubble masonry slope protection flanking the portal. Built for the Oregon Eastern, this Southern Pacific Common Standard tunnel is contemporary with those built by different contractors for the California Northeastern at the south end of the Natron Cutoff (see Tunnel 17, HAER CA-218, and Tunnel 18, HAER CA-219). - Southern Pacific Railroad Natron Cutoff, Tunnel 22, Milepost 581.85, Oakridge, Lane County, OR

  8. 2. West portal of Tunnel 23, view to the westnorthwest, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. West portal of Tunnel 23, view to the west-northwest, 135mm lens. Note the use of concrete face and wingwalls, with dressed stone voussoirs, wingwall coping, concrete parapet with stone belt course and coping, and rubble masonry slope protection flanking the portal. Built for the Oregon Eastern, this Southern Pacific Common Standard tunnel is contemporary with those built by different contractors for the California Northeastern at the south end of the Natron Cutoff (see Tunnel 17, HAER CA-218, and Tunnel 18, HAER CA-219). - Southern Pacific Railroad Natron Cutoff, Tunnel 23, Milepost 584.5, Westfir, Lane County, OR

  9. Portal flow modulation in auxiliary partial orthotopic liver transplantation.

    PubMed

    Rela, Mohamed; Bharathan, Anand; Palaniappan, Kumar; Cherian, Pradeep T; Reddy, Mettu S

    2015-05-01

    APOLT is a suitable technique of liver transplantation in patients with ALF and some types of MLD. Portal venous steal is a problem with this procedure that leads to graft dysfunction and failure. Modulation of the portal flow to the graft and native liver can help in preventing this problem. We discuss the pathophysiology of this complication, review available literature regarding its management, and describe our results using the technique of graded hemiportal banding to achieve adequate perfusion for the graft and native liver. PMID:25692474

  10. EUFAR the unique portal for airborne research in Europe

    NASA Astrophysics Data System (ADS)

    Gérard, Elisabeth; Brown, Philip

    2016-04-01

    Created in 2000 and supported by the EU Framework Programmes since then, EUFAR was born out of the necessity to create a central network and access point for the airborne research community in Europe. With the aim to support researchers by granting them access to research infrastructures, not accessible in their home countries, EUFAR also provides technical support and training in the field of airborne research for the environmental and geo-sciences. Today, EUFAR2 (2014-2018) coordinates and facilitates transnational access to 18 instrumented aircraft and 3 remote-sensing instruments through the 13 operators who are part of EUFAR's current 24-partner European consortium. In addition, the current project supports networking and research activities focused on providing an enabling environment for and promoting airborne research. The EUFAR2 activities cover three objectives, supported by the internet website www.eufar.net: (I - Institutional) improvement of the access to the research infrastructures and development of the future fleet according to the strategic advisory committee (SAC) recommendations; (ii - Innovation) improvement of the scientific knowledge and promotion of innovating instruments, processes and services for the emergence of new industrial technologies, with an identification of industrial needs by the SAC; (iii - Service) optimisation and harmonisation of the use of the research infrastructures through the development of the community of young researches in airborne science, of the standards and protocols and of the airborne central database. With the launch of a brand new website (www.eufar.net) in mid-November 2015, EUFAR aims to improve user experience on the website, which serves as a source of information and a hub where users are able to collaborate, learn, share expertise and best practices, and apply for transnational access, and education and training funded opportunities within the network. With its newly designed eye-catching interface

  11. Development of position sensitive proportional counters for hot particle detection in laundry and portal monitors

    SciTech Connect

    Shonka, J.J.; Schwahn, S.O.; Bennett, T.E.; Misko, D.J.

    1992-09-01

    This report summarizes research which demonstrates the use of position sensitive proportional counters in contamination monitoring systems. Both laundry monitoring and portal monitoring systems were developed. The laundry monitor was deployed at a nuclear power plant where it was used to monitor clothing during an outage. Position sensitive proportional counter based contamination monitoring systems were shown to have significant advantages over systems using conventional proportional counters. These advantages include the ability to directly measure the area and quantity of contamination. This capability permits identification of hot particles. These systems are also capable of self calibration via internal check sources. Systems deployed with this technology should benefit from reduced complexity, cost and maintenance. The inherent reduction of background that occurs when the counter is electronically divided into numerous detectors permits operation in high background radiation fields and improves detection limits over conventional technology.

  12. Transsplenic portal vein reconstruction-transjugular intrahepatic portosystemic shunt in a patient with portal and splenic vein thrombosis.

    PubMed

    Salsamendi, Jason T; Gortes, Francisco J; Shnayder, Michelle; Doshi, Mehul H; Fan, Ji; Narayanan, Govindarajan

    2016-09-01

    Portal vein thrombosis (PVT) is a potential complication of cirrhosis and can worsen outcomes after liver transplant (LT). Portal vein reconstruction-transjugular intrahepatic portosystemic shunt (PVR-TIPS) can restore flow through the portal vein (PV) and facilitate LT by avoiding complex vascular conduits. We present a case of transsplenic PVR-TIPS in the setting of complete PVT and splenic vein (SV) thrombosis. The patient had a 3-year history of PVT complicated by abdominal pain, ascites, and paraesophageal varices. A SV tributary provided access to the main SV and was punctured percutaneously under ultrasound scan guidance. PV access, PV and SV venoplasty, and TIPS placement were successfully performed without complex techniques. The patient underwent LT with successful end-to-end anastomosis of the PVs. Our case suggests transsplenic PVR-TIPS to be a safe and effective alternative to conventional PVR-TIPS in patients with PVT and SV thrombosis. PMID:27594947

  13. [Portal vein thrombosis and rupture of the esophagus secondary to a barotrauma].

    PubMed

    Prignet, J M; Duval, J L; Raynard, B; Louvety, S; Flandrin, P; Thouard, H; Künkel, D

    1996-02-01

    Portal vein thrombosis complicating a trauma is rare. We report a case of portal vein thrombosis associated with esophageal rupture after a blast injury due to the explosion of a pressurized nitrogen bottle. Portal vein thrombosis was discovered during oesophageal reconstruction, 70 days after the initial injury. A favorable outcome was observed. PMID:8734315

  14. Probing Conserved Helical Modules of Portal Complexes by Mass Spectrometry based Hydrogen/deuterium Exchange

    PubMed Central

    Kang, Sebyung; Poliakov, Anton; Sexton, Jennifer; Renfrow, Matthew B.; Prevelige, Peter E.

    2008-01-01

    The dsDNA bacteriophage P22 has a ring shaped dodecameric complex composed of the 84 kDa portal protein subunit which forms the central channel of the phage’s DNA packaging motor. The overall morphology of the P22 portal complex is similar to that of the portal complexes of Phi29, SPP1, T3, T7 phages and herpes simplex virus. Secondary structure prediction of P22 portal protein and its threading onto the crystal structure of the Phi29 portal complexes suggested that P22 portal protein complex shares conserved helical modules which were found in the dodecameric interfaces of the Phi29 portal complex. To identify the amino acids involved in inter-subunit contacts in the P22 portal ring complexes and validate the threading model, we performed comparative hydrogen/deuterium exchange analysis of monomeric and in vitro assembled portal proteins of P22 and the dodecameric Phi29 portal. Hydrogen/deuterium exchange experiments provided evidence of inter-subunit interactions in the P22 portal complex similar to those in the Phi29 portal which map to the regions predicted to be conserved helical modules. PMID:18621389

  15. Library Subject Portals: An Investigation of Possibilities for the University of the Witwatersrand Library

    ERIC Educational Resources Information Center

    Ubogu, Felix N.; Kekana, Arthur; Roberts, Charl

    2006-01-01

    Purpose: To examine and discuss the features of library portals and suggest further development of these research tools. Design/methodology/approach: The two categories of library portals (horizontal or public, and vertical) were examined to establish the characteristics of some of the portal software available in the marketplace. The study…

  16. Quantitative Analysis of the Usage of the COSMOS Science Education Portal

    ERIC Educational Resources Information Center

    Sotiriou, Sofoklis; Bogner, Franz X.; Neofotistos, George

    2011-01-01

    A quantitative method of mapping the web usage of an innovative educational portal is applied to analyze the behaviour of users of the COSMOS Science Education Portal. The COSMOS Portal contains user-generated resources (that are uploaded by its users). It has been designed to support a science teacher's search, retrieval and access to both,…

  17. Design and Development of a Chemistry Subject Portal at Panjab University Library, India

    ERIC Educational Resources Information Center

    Singh, Neeraj Kumar; Mahajan, Preeti

    2010-01-01

    Purpose: This paper aims to give a brief description of some chemistry portals available worldwide, followed by a description of the chemistry portal developed for Panjab University Library, Chandigarh (India). Design/methodology/approach: A well-structured chemistry portal was designed for chemistry and its allied departments at Panjab University…

  18. Surgical Access to Jejunal Veins for Local Thrombolysis and Stent Placement in Portal Vein Thrombosis

    SciTech Connect

    Schellhammer, Frank; Esch, Jan Schulte am; Hammerschlag, Sascha; Knoefel, Wolfram Trudo; Fuerst, Guenter

    2008-07-15

    Portal vein thrombosis is an infrequent entity, which may cause high morbidity and mortality. We report a case of portal vein thrombosis due to benign stenosis following partial pancreatoduodenectomy with segmental replacement of the portal vein by a Gore-tex graft. Using a surgical access to jenunal veins, local thrombolysis, mechanical fragmentation of thrombus, and stent placement were successfully performed.

  19. PROPERTIES OF 42 SOLAR-TYPE KEPLER TARGETS FROM THE ASTEROSEISMIC MODELING PORTAL

    SciTech Connect

    Metcalfe, T. S.; Mathur, S.; Creevey, O. L.; Doğan, G.; Christensen-Dalsgaard, J.; Karoff, C.; Trampedach, R.; Xu, H.; Bedding, T. R.; Benomar, O.; Chaplin, W. J.; Campante, T. L.; Davies, G. R.; Brown, B. P.; Buzasi, D. L.; Çelik, Z.; Cunha, M. S.; Deheuvels, S.; Derekas, A.; Mauro, M. P. Di; and others

    2014-10-01

    Recently the number of main-sequence and subgiant stars exhibiting solar-like oscillations that are resolved into individual mode frequencies has increased dramatically. While only a few such data sets were available for detailed modeling just a decade ago, the Kepler mission has produced suitable observations for hundreds of new targets. This rapid expansion in observational capacity has been accompanied by a shift in analysis and modeling strategies to yield uniform sets of derived stellar properties more quickly and easily. We use previously published asteroseismic and spectroscopic data sets to provide a uniform analysis of 42 solar-type Kepler targets from the Asteroseismic Modeling Portal. We find that fitting the individual frequencies typically doubles the precision of the asteroseismic radius, mass, and age compared to grid-based modeling of the global oscillation properties, and improves the precision of the radius and mass by about a factor of three over empirical scaling relations. We demonstrate the utility of the derived properties with several applications.

  20. Properties of 75 Solar-type Kepler Targets from the Asteroseismic Modeling Portal

    NASA Astrophysics Data System (ADS)

    Metcalfe, Travis S.; Kepler Asteroseismic Science Consortium

    2015-01-01

    Recently the number of main-sequence and subgiant stars exhibiting solar-like oscillations that are resolved into individual mode frequencies has increased dramatically. While only a few such data sets were available for detailed modeling just a decade ago, the Kepler mission has produced suitable observations for hundreds of new targets. This rapid expansion in observational capacity has been accompanied by a shift in analysis and modeling strategies to yield uniform sets of derived stellar properties more quickly and easily. We use previously published asteroseismic and spectroscopic data sets to provide a uniform analysis of 75 solar-type Kepler targets from the Asteroseismic Modeling Portal (AMP). We find that fitting the individual frequencies typically doubles the precision of the asteroseismic radius, mass and age compared to grid-based modeling of the global oscillation properties, and improves the precision of the radius and mass by about a factor of three over empirical scaling relations. We demonstrate the utility of the derived properties with several applications.