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Sample records for sri lankan population

  1. Genetic diversity of variants involved in drug response and metabolism in Sri Lankan populations: implications for clinical implementation of pharmacogenomics

    PubMed Central

    Chan, Sze Ling; Samaranayake, Nilakshi; Ross, Colin J.D.; Toh, Meng Tiak; Carleton, Bruce; Hayden, Michael R.; Teo, Yik Ying; Dissanayake, Vajira H.W.

    2016-01-01

    Background Interpopulation differences in drug responses are well documented, and in some cases they correspond to differences in the frequency of associated genetic markers. Understanding the diversity of genetic markers associated with drug response across different global populations is essential to infer population rates of drug response or risk for adverse drug reactions, and to guide implementation of pharmacogenomic testing. Sri Lanka is a culturally and linguistically diverse nation, but little is known about the population genetics of the major Sri Lankan ethnic groups. The objective of this study was to investigate the diversity of pharmacogenomic variants in the major Sri Lankan ethnic groups. Methods We examined the allelic diversity of more than 7000 variants in genes involved in drug biotransformation and response in the three major ethnic populations of Sri Lanka (Sinhalese, Sri Lankan Tamils, and Moors), and compared them with other South Asian, South East Asian, and European populations using Wright’s Fixation Index, principal component analysis, and STRUCTURE analysis. Results We observed overall high levels of similarity within the Sri Lankan populations (median FST=0.0034), and between Sri Lankan and other South Asian populations (median FST=0.0064). Notably, we observed substantial differentiation between Sri Lankan and European populations for important pharmacogenomic variants related to warfarin (VKORC1 rs9923231) and clopidogrel (CYP2C19 rs4986893) response. Conclusion These data expand our understanding of the population structure of Sri Lanka, provide a resource for pharmacogenomic research, and have implications for the clinical use of genetic testing of pharmacogenomic variants in these populations. PMID:26444257

  2. Sri Lankan Teachers' Development.

    ERIC Educational Resources Information Center

    Dharmadasa, Kiri H.; And Others

    Sri Lanka has a literacy rate of 90 percent despite a gross national product per capita of only $584. It has nearly 190,000 teachers of whom 50,000 were recruited between 1985 and 1995, working in 10,000 public schools (primary through college). Following the Hindu and Buddhist traditions of Sri Lanka, teachers are greatly respected and seen as…

  3. Evaluation of Common Type 2 Diabetes Risk Variants in a South Asian Population of Sri Lankan Descent

    PubMed Central

    Hassanali, Neelam; De Silva, N. Maneka G.; Robertson, Neil; Rayner, N. William; Barrett, Amy; Bennett, Amanda J.; Groves, Christopher J.; Matthews, David R.; Katulanda, Prasad; Frayling, Timothy M.; McCarthy, Mark I.

    2014-01-01

    Introduction Most studies seeking common variant associations with type 2 diabetes (T2D) have focused on individuals of European ancestry. These discoveries need to be evaluated in other major ancestral groups, to understand ethnic differences in predisposition, and establish whether these contribute to variation in T2D prevalence and presentation. This study aims to establish whether common variants conferring T2D-risk in Europeans contribute to T2D-susceptibility in the South Asian population of Sri Lanka. Methodology Lead single nucleotide polymorphism (SNPs) at 37 T2D-risk loci attaining genome-wide significance in Europeans were genotyped in 878 T2D cases and 1523 normoglycaemic controls from Sri Lanka. Association testing was performed by logistic regression adjusting for age and sex and by the Cochran-Mantel-Haenszel test after stratifying according to self-identified ethnolinguistic subgroup. A weighted genetic risk score was generated to examine the combined effect of these SNPs on T2D-risk in the Sri Lankan population. Results Of the 36 SNPs passing quality control, sixteen showed nominal (p<0.05) association in Sri Lankan samples, fifteen of those directionally-consistent with the original signal. Overall, these association findings were robust to analyses that accounted for membership of ethnolinguistic subgroups. Overall, the odds ratios for 31 of the 36 SNPs were directionally-consistent with those observed in Europeans (p = 3.2×10−6). Allelic odds ratios and risk allele frequencies in Sri Lankan subjects were not systematically different to those reported in Europeans. Genetic risk score and risk of T2D were strongly related in Sri Lankans (per allele OR 1.10 [95%CI 1.08–1.13], p = 1.2×10−17). Conclusion Our data indicate that most T2D-risk variants identified in Europeans have similar effects in South Asians from Sri Lanka, and that systematic difference in common variant associations are unlikely to explain inter-ethnic differences

  4. Nonmetric tooth crown traits in a Sri Lankan aboriginal Vedda population.

    PubMed

    Peiris, H R D; Arambawatta, A K S; Hewapathirana, T N; Nanayakkara, C D; Chandrasekara, M; Wickramanayake, E

    2011-12-01

    This study was conducted to determine the frequencies of non-metric tooth crown traits of Vedda of Sri Lanka and to investigate the affinities of these morphological variations with those of other world populations. Fifty dental plaster casts were observed. The Arizona State University dental anthropology system was adopted for classification of the 16 traits observed. We used 13 traits to compare the Vedda and other world populations. Using the frequencies of 13 traits, Smith Mean Measure of Divergence was calculated to determine inter-population distances. Affinities among the Vedda and other world populations were expressed in two dimensions of the principal coordinate analysis. Cusp number in mandibular second molar and hypocone absence in maxillary second molar had the highest frequency at 95.9% and 93.8%, respectively. Shovelling, double shovelling in the maxillary central incisor and deflecting wrinkle in the mandibular first molar had the lowest frequency at 0%. The principal coordinate analysis showed that Sino American and Western Eurasian populations were separated in negative and positive directions in the first principal coordinate axis. Vedda located with the Western Eurasian population groups. Sahul and Sunda Pacific populations located in the intermediate position between Sino American and Western Eurasian populations. The dental phenotype of Vedda has close affinities with those of early south Asian populations. They are far different from Sino American and Sunda pacific populations. Vedda shows closer affinities to Sahul Pacific and South African (Bantu) populations. PMID:21975363

  5. Variations in the Root Form and Root Canal Morphology of Permanent Mandibular First Molars in a Sri Lankan Population

    PubMed Central

    Peiris, Roshan; Malwatte, Uthpala; Abayakoon, Janak; Wettasinghe, Anuradha

    2015-01-01

    The present study was conducted to determine the number of roots and morphology of the root canal system of permanent mandibular first molars (M1) in a Sri Lankan population. Sample of 529 M1 teeth was used. The number of roots was examined and the lengths of the mesial and distal roots were measured to the nearest 0.01 mm. Vacuum injection protocol was used to inject China ink into the root canal system, making it transparent. Root canal morphology was recorded using Vertucci's classification. Presence of furcation canals, position of lateral canals, intercanal communications, level of bifurcation, and convergence of the root canal system were recorded. M1 showed three roots in 4.1% of the sample. Commonest root canal morphology of the mesial root was type IV and the distal root was type I. The level of bifurcation of the root canals was commonly observed in the cervical one-third of the root while convergence was observed in the apical one-third in both roots. Prevalence of three rooted mandibular first molars is less than 5%. Mesial root showed the most variable canal morphology. Prevalence of furcation canals was 1.5% while that of middle mesial canals was 0.2%. PMID:26351583

  6. Energy and nutrient intakes among Sri Lankan adults

    PubMed Central

    2014-01-01

    Introduction The epidemic of nutrition related non-communicable diseases such as type 2 diabetes mellitus and obesity has reached to epidemic portion in the Sri Lanka. However, to date, detailed data on food consumption in the Sri Lankan population is limited. The aim of this study is to identify energy and major nutrient intake among Sri Lankan adults. Methods A nationally-representative sample of adults was selected using a multi-stage random cluster sampling technique. Results Data from 463 participants (166 Males, 297 Females) were analyzed. Total energy intake was significantly higher in males (1913 ± 567 kcal/d) than females (1514 ± 458 kcal/d). However, there was no significant gender differences in the percentage of energy from carbohydrate (Male: 72.8 ± 6.4%, Female: 73.9 ± 6.7%), fat (Male: 19.9 ± 6.1%, Female: 18.5 ± 5.7%) and proteins (Male: 10.6 ± 2.1%, Female: 10.9 ± 5.6%). Conclusion The present study provides the first national estimates of energy and nutrient intake of the Sri Lankan adult population. PMID:25067954

  7. L2 Reading Motivation among Sri Lankan University Students

    ERIC Educational Resources Information Center

    Dhanapala, Kusumi Vasantha; Hirakawa, Yukiko

    2016-01-01

    This study investigated the extent of the motivational processes that facilitated the text comprehension among 406 Sri Lankan university students in Sri Lanka. Students' L2 text comprehension and reading motivation were assessed using a reading comprehension test and a reading motivation and attitude questionnaire. The Principal Componential…

  8. HLA-B27 allele frequency in Sri Lankan patients with spondyloarthritides.

    PubMed

    Kidnapillai, S; Sirisena, N D; Dissanayake, V H

    2016-06-01

    This preliminary study aims to describe the HLA-B27 allele frequency in Sri Lankan patients with spondyloarthritides (SA). An anonymised database of 373 Sri Lankan patients with SA referred for HLA-B27 testing was retrospectively analysed. Eighty five (22.8%) patients were positive for the HLA-B27 allele. A male preponderance was observed among the positives. The HLA-B27 allele frequency in this sample of patients with SA was relatively low compared to published studies in other populations. Further research is needed to identify the predominant subtypes of the allele to determine which subtypes are the most prevalent in a larger sample of Sri Lankan patients with SA, and to define their association with the specific types of SA. PMID:27423748

  9. An International Partnership Promoting Psychological Well-Being in Sri Lankan Schools

    ERIC Educational Resources Information Center

    Nastasi, Bonnie K.; Jayasena, Asoka N. S.

    2014-01-01

    This article illustrates the application of psychological and educational consultation in an international setting. With the goal of promoting psychological well-being of the school-age population, a partnership was formed between an American school psychologist and a Sri Lankan educational sociologist and teacher educator. The partners, or…

  10. Beliefs of Sri Lankan Medical Students about Wife Beating

    ERIC Educational Resources Information Center

    Haj-Yahia, Muhammad M.; de Zoysa, Piyanjali

    2007-01-01

    The article presents the results of a study on beliefs about wife beating conducted among 476 Sri Lankan medical students. Participants fill out a self-administered questionnaire, which examines six beliefs about wife beating. Most students tend to justify wife beating, to believe women benefit from wife beating, and to believe the wife bears more…

  11. Self and Modernism in Sri Lankan Poetry in English.

    ERIC Educational Resources Information Center

    Dissanayake, Wimal

    1990-01-01

    Examines the relationship between self and modernism in the context of Sri Lankan poetry in English. The dissolution of the unitary self and the problem of its representation in literature are closely linked to the dynamics of writing in English in a country in the Outer Circle. (24 references) (JL)

  12. The effect of dietary changes on distinct components of the metabolic syndrome in a young Sri Lankan population at high risk of CVD.

    PubMed

    Guess, Nicola; Wijesuriya, Mahen; Vasantharajah, Laksha; Gulliford, Martin; Viberti, Giancarlo; Gnudi, Luigi; Karalliedde, Janaka

    2016-08-01

    South Asian populations are predisposed to early onset of the metabolic syndrome. Lifestyle intervention programmes have demonstrated a reduction in the metabolic syndrome and CVD risk; however, the most effective components of the multi-faceted lifestyle interventions are unknown. We studied 2637 Sri Lankan males (n 1237) and females (n 1380), with a mean BMI of 23·9 (sd 4·2) kg/m2, aged 22·5 (sd 10·0) years, who had participated in a 5-year lifestyle-modification programme to examine the effect of dietary changes on distinct components of the metabolic syndrome. The dietary intervention comprised advice to replace polished starches with unpolished starches, high-fat meat and dairy products with low-fat products and high-sugar beverages and snacks with low-sugar varieties. For the purposes of this analysis, data from the control and intensive lifestyle groups were combined. Anthropometric and biochemical data were recorded, and a FFQ was completed annually. Multiple regression was used to determine the effect of the dietary changes on distinct components of the metabolic syndrome. The ratio unpolished:polished rice was inversely related to change in fasting glucose (β=-0·084, P=0·007) and TAG (β=-0·084, P=0·005) and positively associated with change in HDL-cholesterol (β=0·066, P=0·031) at the 5-year follow-up after controlling for relevant confounders. Red meat intake was positively associated with fasting glucose concentrations (β=0·05, P=0·017), whereas low-fat (β=-0·046, P=0·018) but not high-fat dairy products (β=0·003, P=0·853) was inversely related to glucose tolerance at the follow-up visit. Replacement of polished with unpolished rice may be a particularly effective dietary advice in this and similar populations. PMID:27358019

  13. Gender Equity in Science and Technology in Sri Lankan Universities

    NASA Astrophysics Data System (ADS)

    Malmini, Ranasinghe

    2009-04-01

    Women's composition in the field of science and technology (S&T) in the university system of Sri Lanka was analyzed for the last 12 years. All state universities, including older established and newly introduced S&T oriented, were considered. Sri Lanka data revealed a general increase in female students. In university admissions, the proportion of women in bioscience is more than twice that of women in physical science. A very high percentage of students is majoring in physics. The female qualified percentage to enter university has risen from 56% to 62% in bioscience and from 24% to 32% in physical science. Physical science has seen an increase of qualifying females in the last 12 years. In Sri Lanka, there are about 2,250 university academic staff in S&T, about 36% of whom are women. Only a handful of women physicists work at Sri Lankan state universities; therefore, information on every woman physicist in state universities is given.

  14. The regional sero-epidemiology of rhinosporidiosis in Sri Lankan humans and animals.

    PubMed

    Sudasinghe, T; Rajapakse, R P V J; Perera, N A N D; Kumarasiri, P V R; Eriyagama, N B; Arseculeratne, S N

    2011-01-01

    No data is available in the world literature on serum anti-rhinosporidial antibody levels in animals, and as far as we aware this is the first report. Although rhinosporidiosis in farm and domestic animals has been widely reported from other countries, rhinosporidiosis in animals has not been reported in Sri Lanka, though this country has the highest world-wide prevalence of human rhinosporidiosis on a unit-population basis. Serum IgG titres in 6 species of Sri Lankan animals (buffalo, cat, cattle, dog, goat, horse; total 291) were assayed by the Immuno blot (dot-ELISA) method on nitrocellulose paper and were compared with serum IgG titres in normal Sri Lankan human subjects (total 211) in different geographical areas, and in human Sri Lankan patients with rhinosporidiosis as reference values (total 36). Sensitization to rhinosporidial antigen(s) was detected in all 6 species of animals and the highest titres (1/3200) were found in cats, and free-grazing horses. Cattle showed higher levels of antibody than buffaloes. The titres in these animals are compared with world reports on overt rhinosporidiosis in these species, and with titres in normal Sri Lankan humans. Human, but not animal titres showed variations compatible with the regional prevalence of rhinosporidiosis. The variations in titres in animals especially horses, were probably more related to their mode of feeding, while in humans the titres in normal persons were probably related to the rhinosporidial-endemicity of their respective regions. No conclusions from sero-positivity in animals could be made regarding the absence of reports on rhinosporidiosis as an overt disease in these Sri Lankan animal species but the possibility of a genetically-determined insusceptibility to rhinosporidiosis in Sri Lanka, is considered. Rhinosporidium seeberi-specific PCR positive reactions were obtained with nasal scrapings from cattle that microscopically showed PAS+ bodies that were compatible with rhinosporidial

  15. Examining Washback: The Sri Lankan Impact Study.

    ERIC Educational Resources Information Center

    Wall, Dianne; Alderson, J. Charles

    A study in Sri Lanka concerning the effects of second language tests, specifically the O-Level examination in English as a Second Language, on classroom language instruction is reported. The study investigates the phenomenon of washback or backwash, the influence of testing on instruction. It is cited as the only known research investigating…

  16. Sri Lankan Teachers' Preferred Modes of Helping Students.

    ERIC Educational Resources Information Center

    Dharmadasa, Kiri H.; Gorrell, Jeffrey

    Citing research indicating that U.S. teachers commonly use verbal persuasion techniques to help low achieving students, this study extends the research to Sri Lanka to explore differences in helping strategies adopted by teachers across cultures. Study participants were 237 Sri Lanka teachers who represented the majority Sinhalese population and…

  17. Arterial stiffness & Sri Lankan chronic kidney disease of unknown origin

    PubMed Central

    Gifford, Fiona; Kimmitt, Robert; Herath, Chula; Webb, David J; Melville, Vanessa; Siribaddana, Sisira; Eddleston, Michael; Dhaun, Neeraj

    2016-01-01

    Chronic kidney disease (CKD) is common and independently associated with cardiovascular disease (CVD). Arterial stiffness contributes to CVD risk in CKD. In many developing countries a considerable proportion of CKD remains unexplained, termed CKDu. We assessed arterial stiffness in subjects with Sri Lankan CKDu, in matched controls without CKD and in those with defined CKD. Aortic blood pressure (BP), pulse wave velocity (PWV) and augmentation index (AIx) were assessed in 130 subjects (50 with CKDu, 45 with CKD and 35 without CKD) using the validated TensioMed™ Arteriograph monitor. Brachial and aortic BP was lower in controls than in CKDu and CKD subjects but no different between CKDu and CKD. Controls had a lower PWV compared to subjects with CKDu and CKD. Despite equivalent BP and renal dysfunction, CKDu subjects had a lower PWV than those with CKD (8.7 ± 1.5 vs. 9.9 ± 2.2 m/s, p < 0.01). Excluding diabetes accentuated the differences in PWV seen between groups (controls vs. CKDu vs. CKD: 6.7 ± 0.9 vs. 8.7 ± 1.5 vs. 10.4 ± 1.5 m/s, p < 0.001 for all). Sri Lankan CKDu is associated with less arterial stiffening than defined causes of CKD. Whether this translates to lower cardiovascular morbidity and mortality long term is unclear and should be the focus of future studies. PMID:27586642

  18. Arterial stiffness &Sri Lankan chronic kidney disease of unknown origin.

    PubMed

    Gifford, Fiona; Kimmitt, Robert; Herath, Chula; Webb, David J; Melville, Vanessa; Siribaddana, Sisira; Eddleston, Michael; Dhaun, Neeraj

    2016-01-01

    Chronic kidney disease (CKD) is common and independently associated with cardiovascular disease (CVD). Arterial stiffness contributes to CVD risk in CKD. In many developing countries a considerable proportion of CKD remains unexplained, termed CKDu. We assessed arterial stiffness in subjects with Sri Lankan CKDu, in matched controls without CKD and in those with defined CKD. Aortic blood pressure (BP), pulse wave velocity (PWV) and augmentation index (AIx) were assessed in 130 subjects (50 with CKDu, 45 with CKD and 35 without CKD) using the validated TensioMed™ Arteriograph monitor. Brachial and aortic BP was lower in controls than in CKDu and CKD subjects but no different between CKDu and CKD. Controls had a lower PWV compared to subjects with CKDu and CKD. Despite equivalent BP and renal dysfunction, CKDu subjects had a lower PWV than those with CKD (8.7 ± 1.5 vs. 9.9 ± 2.2 m/s, p < 0.01). Excluding diabetes accentuated the differences in PWV seen between groups (controls vs. CKDu vs. CKD: 6.7 ± 0.9 vs. 8.7 ± 1.5 vs. 10.4 ± 1.5 m/s, p < 0.001 for all). Sri Lankan CKDu is associated with less arterial stiffening than defined causes of CKD. Whether this translates to lower cardiovascular morbidity and mortality long term is unclear and should be the focus of future studies. PMID:27586642

  19. Differences in selected lifestyle risk factors for cardiovascular disease between Sri Lankans in Oslo, Norway, and in Kandy, Sri Lanka.

    PubMed

    Tennakoon, Sampath U B; Kumar, Bernadette N; Meyer, Haakon E

    2015-03-01

    Sri Lankans in Oslo have previously been shown to have lower risk of cardiovascular disease compared with those in Kandy, Sri Lanka. Here we present lifestyle risk factors for cardiovascular diseases: frequency and type of fat consumed, frequency of fruit and vegetable intake, alcohol consumption, and leisure time physical activity between 1145 Sri Lankans living in Oslo and 678 Tamils and Sinhalese Sri Lankans living in Kandy as possible explanatory factors for the differences observed. Those in Oslo were consuming healthier fats and reported higher levels of physical activity but frequency of vegetable and fruit consumption was lower. Alcohol consumption among women was negligible. Type of fats consumed might be protective for Oslo group compared with predominantly saturated fat diet in Kandy. Higher leisure time physical activity may also be protective for the Oslo group. Higher frequency of consumption of vegetables and fruits may be beneficial in Kandy. PMID:23666830

  20. Dietary supplement intake in national-level Sri Lankan athletes.

    PubMed

    de Silva, Angela; Samarasinghe, Yasas; Senanayake, Dhammika; Lanerolle, Pulani

    2010-02-01

    Intake of dietary supplements is widespread among athletes in developed countries. This study evaluated the use of dietary supplements in athletes from a developing country. Dietary supplementation practices of 113 national-level athletes age 15-35 yr in Sri Lanka were assessed. All athletes from track-and-field, badminton, football, swimming, cycling, and karate squads who consented to participate in the study were administered an anonymous questionnaire by an interviewer. Information on number of supplements taken, frequency of use, nature of product, rationale, sources of advice, and reasons for taking supplements was obtained. Most athletes (94%) consumed dietary supplements. On average, 3.7 products/day were consumed. Footballers had significantly lower intake of supplements than other athletes (footballers 71%, others 98%; p < .05). They also consumed fewer products per day (footballers 0.7, others 3.5; p < .05). Popular supplements included multivitamins, vitamin E, calcium, energy foods and drinks, and creatine. Multiple supplement use was common, with 29% athletes taking 4 products/day. The athletes sought advice on supplement use from sports doctors (45%), team coaches (40%), or friends (15%). Most took supplements to improve performance (79%), and 19% claimed to take supplements to improve their overall health status. Dietary supplement use is widespread among national-level Sri Lankan athletes. The ad hoc use of supplements indicates that educational intervention in the sporting community is essential. PMID:20190347

  1. The deuterium oxide-to-the-mother method documents adequate breast-milk intake among Sri Lankan infants

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The WHO recommends that exclusive breastfeeding should last up to 6 months. However, human milk intake of Sri Lankan infants has not been quantified scientifically. The objectives of this study were to measure the human milk intake of Sri Lankan infants during the first 6 months of age and to docume...

  2. Negative Trauma Appraisals and PTSD Symptoms in Sri Lankan Adolescents.

    PubMed

    Ponnamperuma, Thyagi; Nicolson, Nancy A

    2016-02-01

    The cognitive model posits that negative appraisals play an important role in posttraumatic stress disorder, in children as well as in adults. This study examined correlates of negative appraisals in relation to trauma exposure and their relationship to posttraumatic stress symptoms (PTSS) in 414 Sri Lankan adolescents, aged 12 to 16, living in areas impacted in varying degrees by the 2004 tsunami. In 2008, participants completed measures of negative appraisals, lifetime traumatic events, posttraumatic stress symptoms, internalizing symptoms, ongoing adversity, and social support. The majority (70 %) of the participants reported multiple traumatic events; 25 % met DSM-IV criteria for full or partial PTSD. Adolescents who had experienced more severe events, abusive events, greater cumulative trauma, or greater current adversity reported more negative appraisals. In regression analyses controlling for known risk factors such as female gender, cumulative trauma, ongoing adversity, and low social support, negative appraisals were the best predictor of PTSS, explaining 22 % of the variance. This relationship appeared specific to PTSS, as negative appraisals did not predict internalizing symptoms. Findings confirm the link between negative cognitions concerning traumatic events and persistent PTSS in adolescents, but longitudinal studies are needed to determine whether appraisals contribute to symptom maintenance over time. PMID:25691386

  3. Sri Lanka in global medical research: a scientific analysis of the Sri Lankan research output during 2000-2009

    PubMed Central

    2012-01-01

    Background Scientific research is an essential component in guiding improvements in health systems. There are no studies examining the Sri Lankan medical research output at international level. The present study evaluated the Sri Lankan research performance in medicine as reflected by the research publications output between years 2000-2009. Methods This study was based on Sri Lankan medical research publication data, retrieved from the SciVerse Scopus® from January 2000 to December 2009. The process of article selection was as follows: Affiliation - 'Sri Lanka' or 'Ceylon', Publication year - 'January 2000 to December 2009' and Subject area - 'Life and Health Sciences'. The articles identified were classified according to disease, medical speciality, institutions, major international collaborators, authors and journals. Results Sri Lanka's cumulative medical publications output between years 2000-2009 was 1,740 articles published in 160 different journals. The average annual publication growth rate was 9.1%. Majority of the articles were published in 'International' (n = 950, 54.6%) journals. Most articles were descriptive studies (n = 611, 35.1%), letters (n-345, 19.8%) and case reports (n = 311, 17.9%). The articles were authored by 148 different Sri Lankan authors from 146 different institutions. The three most prolific local institutions were Universities of; Colombo (n = 547), Kelaniya (n = 246) and Peradeniya (n = 222). Eighty four countries were found to have published collaborative papers with Sri Lankan authors during the last decade. UK was the largest collaborating partner (n = 263, 15.1%). Malaria (n = 75), Diabetes Mellitus (n = 55), Dengue (n = 53), Accidental injuries (n = 42) and Lymphatic filariasis (n = 40) were the major diseases studied. The 1,740 publications were cited 9,708 times, with an average citation of 5.6 per paper. The most cited paper had 203 citations, while there were 597 publications with no citations. The Sri Lankan authors

  4. Occupational exposure of Sri Lankan tea plantation workers to paraquat.

    PubMed

    Chester, G; Gurunathan, G; Jones, N; Woollen, B H

    1993-01-01

    Absorption of the herbicide paraquat (1,1'-dimethyl-4,4'-bipyridinium) by mixer-loaders and spray operators on a Sri Lankan tea plantation was assessed over five consecutive days of spraying. Beginning on the day before spraying started and continuing for each of the five spraying days and for seven days after the last day of spraying, 24-hour urine samples were collected from each of the workers. Potential dermal exposure was assessed during further applications of paraquat on the day after the last day of urine collection. For this purpose two spraying replicates were conducted that involved the handling or spraying of an amount of paraquat equivalent to the maximum used per day in the assessment of absorption. The mixer-loaders and spray operators incurred, on average, approximately equivalent amounts of potential dermal exposure (66 mg and 74 mg paraquat ion, resp.); however, the distribution of the exposure differed. About 86% of the total exposure experienced by the mixer-loaders was to the hands, whereas about 90% of the exposure of the spray operators involved their hands, legs, and feet, in approximately equal proportions. In both cases, 90% or more of the total potential exposure involved parts of the body that were normally uncovered. Despite the evidence of dermal exposure, no paraquat was detected in the workers' urine. This probably was due to the very low concentration of paraquat in the solutions used for spot spraying on tea plantations (0.3-0.4 g paraquat ion per litre), the high standard of personal hygiene exercised by the workers, and the low permeability of human skin to paraquat. PMID:8261566

  5. Chemical characterization and metal abundance in Sri Lankan serpentine soils

    NASA Astrophysics Data System (ADS)

    Vithanage, M. S.; Rajapaksha, A. U.; Ok, Y. S.; Oze, C.

    2012-12-01

    Chemical weathering of ultramafic rocks and their related soils provide localized sources of metal contamination. In Sri Lanka, rural communities live in close proximity to these rocks and soils and utilize associated groundwaters where human intake of these high metal sources may have adverse human health effects. This study investigates metal abundances and variations in Sri Lankan serpentine soils to begin evaluating potential human health hazards. Specifically, we examine serpentinite occurrences at Ussangoda, Wasgamuwa, Ginigalpelessa, and Indikolapelessa located at the geological boundary between the Highland and Vijayan Complexes. The pH of the soils are near neutral (6.26 to 7.69) with soil electrical conductivities (EC) ranging from 33.5 to 129.9 μS cm-1, a range indicative of relatively few dissolved salts and/or major dissolved inorganic solutes. The highest EC is from the Ussangoda soil which may be due to the atmospheric deposition of salt spray from the sea. Organic carbon contents of the soils range from 1.09% to 2.58%. The highest organic carbon percentage is from the Wasgamuwa soil which is located in a protected preserve. X-ray fluorescence (XRF) spectrometry and total metal digestion results show that all serpentine soils are Fe-, Cr-, and Ni-rich with abundant aluminosilicate minerals. Nickel is highest in the Ussangoda soil (6,459 mg kg-1), while Cr (>10,000 mg kg-1), Co (441 mg kg-1) and Mn (2,263 mg kg-1) are highest in the Wasgamuwa serpentine soil. Additionally, Mn (2,200 mg kg-1) and Co (400 mg kg-1) are present at high concentrations in the Wasgamuwa and Ginigalpelessa soils respectively. Electron microprobe mapping demonstrates that these heavy metals are not homogeneously distributed where Cr is specifically associated with Al and Fe phases. Metal speciation of these serpentine soils are currently being investigated using X-ray absorption spectroscopy (XAS) to provide better constraints with regards to their mobility and toxicity.

  6. Tsunami, War, and Cumulative Risk in the Lives of Sri Lankan Schoolchildren

    ERIC Educational Resources Information Center

    Catani, Claudia; Gewirtz, Abigail H.; Wieling, Elizabeth; Schauer, Elizabeth; Elbert, Thomas; Neuner, Frank

    2010-01-01

    This study examines the impact of children's exposure to natural disaster against the backdrop of exposure to other traumatic events and psychosocial risks. One thousand three hundred ninety-eight Sri Lankan children aged 9-15 years were interviewed in 4 cross-sectional studies about exposure to traumatic life events related to the war, the…

  7. Styling One's Own in the Sri Lankan Tamil Diaspora: Implications for Language and Ethnicity

    ERIC Educational Resources Information Center

    Canagarajah, Suresh

    2012-01-01

    This study focuses on the ways youth in the Sri Lankan Tamil diaspora in Canada, Britain, and the United States construct their ethnic identity when proficiency in their heritage language is limited. Though these youth claim only rudimentary proficiency in Tamil and identify English as their dominant language, they are nonetheless able to claim…

  8. Sri Lankan students campaign for rational medicine: the story of SIRHA.

    PubMed

    Ranwella, S

    1993-01-01

    Students Involved in Rational Health Activities (SIRHA) is a group of Sri Lankan medical students dedicated to increasing awareness of rational health care. SIRHA has hosted a seminar on rational therapeutics for medical students. Clinicians and academicians discussed case histories of inappropriate drug treatment at the seminar. A panel organized by the International Advertisers Association addressed the levels of control needed for medical drug advertising. Another seminar focused on how to facilitate the provision of low cost quality drugs based on rational prescriptions to all Sri Lankans. The Director-General of Health Services, the Chairman of the State Pharmaceuticals Corporation, and other government officials discussed drug registration, tenders, local manufacture of drugs, quality assurance, distribution, and pricing. At the annual meeting of the Sri Lankan Medical Association, SIRHA members prepared a leaflet comparing statements on promotional material of pharmaceutical companies with the text of internationally recognized standard works of reference. Company representatives were at the meeting. The Medical Lobby for Appropriate Marketing addressed one of the promotional materials in an August 1993 international letter. SIRHA members have also targeted irrational and misleading advertising of health-related products in the mass media. They have succeeded in bringing about the withdrawal of a misleading ad with unsubstantiated claims by a multinational company operating in Sri Lanka. SIRHA has submitted a complaint to the People's Tribunal on pharmaceutical pricing, unethical promotion, and the availability of an irrationally large number of me-too drugs in Sri Lanka. The Tribunal found the complaint justified and recommended the adoption of regulations proposed by SIRHA. SIRHA continues to monitor pharmaceutical advertising practices in Sri Lanka. It has established good relations with local and international groups. PMID:12319049

  9. Blended Learning in Distance Education: Sri Lankan Perspective

    ERIC Educational Resources Information Center

    Liyanagunawardena, T. R.; Adams, A. A.; Rassool, N.; Williams, S. A.

    2014-01-01

    The purpose of this paper is to explore the implementation of online learning in distance educational delivery at Yellow Fields University (pseudonymous) in Sri Lanka. The implementation of online distance education at the University included the use of blended learning. The policy initiative to introduce online for distance education in Sri Lanka…

  10. Developing government policies for distance education: Lessons learnt from two Sri Lankan case studies

    NASA Astrophysics Data System (ADS)

    Liyanagunawardena, Tharindu Rekha; Adams, Andrew A.; Rassool, Naz; Williams, Shirley A.

    2014-12-01

    Education, especially higher education, is considered vital for maintaining national and individual competitiveness in the global knowledge economy. Following the introduction of its "Free Education Policy" as early as 1947, Sri Lanka is now the best performer in basic education in the South Asian region, with a remarkable record in terms of high literacy rates and the achievement of universal primary education. However, access to tertiary education is a bottleneck, due to an acute shortage of university places. In an attempt to address this problem, the government of Sri Lanka has invested heavily in information and communications technologies (ICTs) for distance education. Although this has resulted in some improvement, the authors of this article identify several barriers which are still impeding successful participation for the majority of Sri Lankans wanting to study at tertiary level. These impediments include the lack of infrastructure/resources, low English language proficiency, weak digital literacy, poor quality of materials and insufficient provision of student support. In the hope that future implementations of ICT-enabled education programmes can avoid repeating the mistakes identified by their research in this Sri Lankan case, the authors conclude their paper with a list of suggested policy options.

  11. Essential drugs and registration of pharmaceuticals: the Sri Lankan experience.

    PubMed Central

    Weerasuriya, K.

    1993-01-01

    Many factors influence the regulation of pharmaceuticals in a country. The essential drugs concept, formulated by the World Health Organization to assist developing countries in selecting appropriate drugs, also provides a basis for regulation. Sri Lanka has long regulated pharmaceuticals as part of its health policy. Over 70% of 3436 pharmaceutical product registrations were found to be drugs (or alternatives) named in the country's essential drugs list. This is despite the fact that product registrations are mainly for the private health care sector, and the list is for the state sector. The essential drugs concept therefore appears to have influenced the pharmaceuticals registered in Sri Lanka. PMID:8490987

  12. The Impact of Education Investment on Sri Lankan Economic Growth

    ERIC Educational Resources Information Center

    Ganegodage, K. Renuka; Rambaldi, Alicia N.

    2011-01-01

    We evaluate the contribution of investment on education to Sri Lanka's economic growth during the period 1959-2008. Physical capital, economic policy changes and the ethnic war are also evaluated due to their substantial importance. This study uses a framework encompassing both the neoclassical and endogenous growth model. The impact of education…

  13. Training Objectives, Transfer, Validation and Evaluation: A Sri Lankan Study

    ERIC Educational Resources Information Center

    Wickramasinghe, Vathsala M.

    2006-01-01

    Using a stratified random sample, this paper examines the training practices of setting objectives, transfer, validation and evaluation in Sri Lanka. The paper further sets out to compare those practices across local, foreign and joint-venture companies based on the assumption that there may be significant differences across companies of different…

  14. Healing through giving testimony: An empirical study with Sri Lankan torture survivors.

    PubMed

    Puvimanasinghe, Teresa S; Price, Ian R

    2016-10-01

    Sri Lanka has recently emerged from a three decade long civil war between government forces and the Liberation Tigers of Tamil Eelam. Behind the actual arena of conflict, forms of organised violence were often perpetrated on ordinary Sri Lankans who came into contact with law enforcement officials and other state authorities. The effects of these encounters on mental health, well-being, and community participation can be severe and long-lasting. Considering the generally poor availability of mental health services in many low-income countries, brief efficient interventions are required to enhance the lives of individuals and their families affected by torture, trauma, or displacement. In this context, the present study evaluated the effectiveness of testimonial therapy in ameliorating the distress of Sri Lankan survivors of torture and ill-treatment. The results indicated that over a 2- to 3-month period, psychosocial functioning was significantly enhanced in the therapy group compared to the waitlist control group. The general benefits of testimonial therapy, the ease with which it can be incorporated into ongoing human rights activities, and its application by trained nonprofessionals encourage greater use of the approach. PMID:27330026

  15. Perceptions of factors contributing to intimate partner violence among Sri Lankan Tamil immigrant women in Canada.

    PubMed

    Hyman, Ilene; Mason, Robin; Guruge, Sepali; Berman, Helene; Kanagaratnam, Pushpa; Manuel, Lisa

    2011-09-01

    In this article we explore Sri Lankan Tamil immigrant women's views on factors contributing to intimate partner violence (IPV). We conducted eight focus groups with young, midlife, and senior women and women who experienced IPV. Three main themes emerged: postmigration sources of stress and conflict, patriarchal social norms that dictated gendered behavior, and individual male attributes and behaviors. Study participants recognized gender inequality and financial dependence as contributing factors and the role of women in promoting marital harmony. Findings suggest that pre- and postmigration factors need to be considered in the prevention of IPV in newcomer communities. PMID:21834718

  16. The Maintenance of Sri Lankan Languages in Australia--Comparing the Experience of the Sinhalese and Tamils in the Homeland

    ERIC Educational Resources Information Center

    Perera, Nirukshi

    2015-01-01

    In the study of language maintenance and shift for migrant groups in Australia, scholars have tended to focus on how personal factors or aspects of life in the host society shape language maintenance patterns. In this study, I explore how factors originating in the homeland affect language maintenance for Sri Lankan migrants in Australia. The aim…

  17. Deep Ocean Tsunami Waves off the Sri Lankan Coast

    NASA Technical Reports Server (NTRS)

    2004-01-01

    The initial tsunami waves resulting from the undersea earthquake that occurred at 00:58:53 UTC (Coordinated Universal Time) on December 26, 2004, off the island of Sumatra, Indonesia, took a little over 2 hours to reach the teardrop-shaped island of Sri Lanka. Additional waves continued to arrive for many hours afterward. At approximately 05:15 UTC, as NASA's Terra satellite passed overhead, the Multi-angle Imaging SpectroRadiometer (MISR) captured this image of deep ocean tsunami waves about 30-40 kilometers from Sri Lanka's southwestern coast. The waves are made visible due to the effects of changes in sea-surface slope on the reflected sunglint pattern, shown here in MISR's 46-degree-forward-pointing camera. Sunglint occurs when sunlight reflects off a water surface in much the same way light reflects off a mirror, and the position of the Sun, angle of observation, and orientation of the sea surface determines how bright each part of the ocean appears in the image. These large wave features were invisible to MISR's nadir (vertical-viewing) camera. The image covers an area of 208 kilometers by 207 kilometers. The greatest impact of the tsunami was generally in an east-west direction, so the havoc caused by the tsunami along the southwestern shores of Sri Lanka was not as severe as along the eastern coast. However, substantial damage did occur in this region' as evidenced by the brownish debris in the water' because tsunami waves can diffract around land masses. The ripple-like wave pattern evident in this MISR image roughly correlates with the undersea boundary of the continental shelf. The surface wave pattern is likely to have been caused by interaction of deep waves with the ocean floor, rather than by the more usually observed surface waves, which are driven by winds. It is possible that this semi-concentric pattern represents wave reflection from the continental land mass; however, a combination of wave modeling and detailed bathymetric data is required to

  18. Impact of Adverse Childhood Experiences on Intimate Partner Violence Perpetration among Sri Lankan Men.

    PubMed

    Fonseka, Ruvani W; Minnis, Alexandra M; Gomez, Anu Manchikanti

    2015-01-01

    In Sri Lanka, over one in three women experience intimate partner violence (IPV) victimization in their lifetime, making it a serious public health concern. Adverse childhood experiences (ACEs) such as child abuse and neglect, witnessing domestic violence, parental separation, and bullying are also widespread. Studies in Western settings have shown positive associations between ACEs and IPV perpetration in adulthood, but few have examined this relationship in a non-Western context. In the present study, we examined the association of ACEs with IPV perpetration among Sri Lankan men surveyed for the UN Multi-Country Study on Men and Violence in Asia and the Pacific. We found statistically significant positive associations between the number of ACE categories (ACE score) and emotional, financial, physical, and sexual IPV perpetration among Sri Lankan men. We analyzed the contributions of each ACE category and found that childhood abuse was strongly associated with perpetration of IPV in adulthood, with sexual abuse associated with the greatest increase in odds of perpetration (Adjusted odds ratio 2.36; 95% confidence interval: 1.69, 3.30). Witnessing abuse of one's mother was associated with the greatest increase in the odds of perpetrating physical IPV (AOR 1.82; 95% CI: 1.29, 2.58), while lack of a male parental figure was not associated with physical IPV perpetration (AOR 0.76; 95% CI: 0.53, 1.09). These findings support a social learning theory of IPV perpetration, in which children who are exposed to violence learn to perpetrate IPV in adulthood. They also suggest that in Sri Lanka, being raised in a female-headed household does not increase the risk of IPV perpetration in adulthood compared to being raised in a household with a male parental figure. The relationship between being raised in a female-headed household (the number of which increased dramatically during Sri Lanka's recent civil war) and perpetration of IPV warrants further study. Interventions that

  19. Impact of Adverse Childhood Experiences on Intimate Partner Violence Perpetration among Sri Lankan Men

    PubMed Central

    Fonseka, Ruvani W.; Minnis, Alexandra M.; Gomez, Anu Manchikanti

    2015-01-01

    In Sri Lanka, over one in three women experience intimate partner violence (IPV) victimization in their lifetime, making it a serious public health concern. Adverse childhood experiences (ACEs) such as child abuse and neglect, witnessing domestic violence, parental separation, and bullying are also widespread. Studies in Western settings have shown positive associations between ACEs and IPV perpetration in adulthood, but few have examined this relationship in a non-Western context. In the present study, we examined the association of ACEs with IPV perpetration among Sri Lankan men surveyed for the UN Multi-Country Study on Men and Violence in Asia and the Pacific. We found statistically significant positive associations between the number of ACE categories (ACE score) and emotional, financial, physical, and sexual IPV perpetration among Sri Lankan men. We analyzed the contributions of each ACE category and found that childhood abuse was strongly associated with perpetration of IPV in adulthood, with sexual abuse associated with the greatest increase in odds of perpetration (Adjusted odds ratio 2.36; 95% confidence interval: 1.69, 3.30). Witnessing abuse of one’s mother was associated with the greatest increase in the odds of perpetrating physical IPV (AOR 1.82; 95% CI: 1.29, 2.58), while lack of a male parental figure was not associated with physical IPV perpetration (AOR 0.76; 95% CI: 0.53, 1.09). These findings support a social learning theory of IPV perpetration, in which children who are exposed to violence learn to perpetrate IPV in adulthood. They also suggest that in Sri Lanka, being raised in a female-headed household does not increase the risk of IPV perpetration in adulthood compared to being raised in a household with a male parental figure. The relationship between being raised in a female-headed household (the number of which increased dramatically during Sri Lanka’s recent civil war) and perpetration of IPV warrants further study. Interventions

  20. Barriers to recovery in communities exposed to disasters: Sri Lankan voices speak.

    PubMed

    Fernando, Gaithri A; Wilkins, Ashley

    2015-01-01

    Disasters experienced by a community place all members at risk for physical and psychological harm. While natural resilience may help many to recover, there may be barriers that hinder the recovery process. This qualitative study was conducted to examine barriers to recovery in a community impacted by both war and the tsunami. A group of 43 ethnically diverse Sri Lankans (F = 63%) participated in six focus groups and provided their perspectives on barriers they perceived to impede their recovery from traumatic events. Grounded-theory-based data analysis revealed culture-general and culture-specific socio-economic, environmental, sociocultural, and individual barriers that participants identified as impeding their recovery. Interventions and health policies targeting these groups could focus on helping communities to overcome these barriers as a means of facilitating recovery in these beleaguered communities. PMID:26087041

  1. Causal thinking after a tsunami wave: karma beliefs, pessimistic explanatory style and health among Sri Lankan survivors.

    PubMed

    Levy, Becca R; Slade, Martin D; Ranasinghe, Padmini

    2009-03-01

    In 2004, one of the largest earthquakes ever recorded led to a tsunami devastating two-thirds of the Sri Lankan coastline. We examined whether certain causal beliefs (attributional style and karma, a Buddhist concept used to explain bad events) are associated with tsunami survivors experiencing PTSD and poor health about six months later. Previous studies of causal beliefs associated with illness following the same traumatic event have focused on Western countries and none have considered the role of karma. We interviewed 264 Sri Lankan tsunami survivors. As predicted, we found that belief in karma and a pessimistic explanatory style are independently associated with poor health and a pessimistic explanatory style is associated with PTSD, after adjusting for relevant factors. Thus, both universal and more culturally specific beliefs may contribute to coping following a natural disaster. PMID:19229624

  2. Effect of Sri Lankan traditional medicine and Ayurveda on Sandhigata Vata (osteoarthritis of knee joint).

    PubMed

    Perera, Pathirage Kamal; Perera, Manaram; Kumarasinghe, Nishantha

    2014-01-01

    Reported case was a 63-year-old female with end-stage osteoarthritis (OA) (Sandhigata Vata) of the left knee joint accompanied by exostoses. Radiology (X-ray) report confirmed it as a Kellgren-Lawrence grade III or less with exostoses. At the beginning, the Knee Society Rating System scores of pain, movement and stability were poor, and function score was fair. Srilankan traditional and Ayurveda medicine treatment was given in three regimens for 70 days. After 70 days, external treatment of oleation and 2 capsules of Shallaki (Boswellia serrata Triana and Planch) and two tablets of Jeewya (comprised of Emblica officinalis Gaertn., Tinospora cordifolia [Willd.] Millers. and Terminalia chebula Retz.), twice daily were continued over 5 months. Visual analogue scale for pain, knee scores in the Knee Society online rating system and a Ayurveda clinical assessment criteria was used to evaluate the effects of treatments in weekly basis. After treatment for 70 days, the Knee Society Rating System scores of pain, movement and stability were also improved up to good level and function score was improved up to excellent level. During the follow-up period, joint symptoms and signs and the knee scores were unchanged. In conclusion, this OA patient's quality of life was improved by the combined treatment of Sri Lankan traditional medicine and Ayurveda. PMID:26195904

  3. Effects of Sri Lankan black tea (Camellia sinensis L.) on pregnancy of rats.

    PubMed

    Ratnasooriya, Wanigasekera D; Fernando, Thimbiripalage S P

    2009-12-01

    The aim of this study was to demonstrate the potential effects of black tea brew of Camellia sinensis using Sri Lankan high grown dust grade no. 1 tea on pregnancy outcome of rats when exposed during early (days 1-7), mid (days 8-14) and late (days 15-21) pregnancy of rats. Different doses of black tea brew (mg/ml/day) was orally administered daily during this period to separate groups of rats (n = 6/group): 84 (equivalent to 1.5 cups), 167 (3 cups), 501 (9 cups), and 1336 (24 cups). The results showed that black tea brew did not significantly (P > 0.05) change the pregnancy outcome (in terms of quantal pregnancy, number of uterine implants, number of viable implants, implantation index, pre-implantation loss, post-implantation loss, gestation index, number of pups born, litter index, live birth index and viability index) and pre- (in terms of length of the implants/foetus, gestation length, cranial length, cranial diameter and tail length of pups) and postnatal (in terms of time taken to open eyes, eruption of incisors and appearance of fur) development. Furthermore, black tea brew did not induce gross morphological birth abnormalities. If the results are applicable to women, it is concluded that even heavy consumption of black tea brew during pregnancy may not be harmful for pregnancy outcome. PMID:19422356

  4. Body composition among Sri Lankan infants by 18*O dilution method and the validity of anthropometric equations to predict body fat against 18*O dilution

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Body composition indicators provide a better guidance for growth and nutritional status of the infants. This study was designed to (1) measure the body composition of the Sri Lankan infants using a reference method, the 18*O dilution method; (2) calculate the body fat content of the infants using pu...

  5. Sustaining food self-sufficiency of a nation: The case of Sri Lankan rice production and related water and fertilizer demands.

    PubMed

    Davis, Kyle Frankel; Gephart, Jessica A; Gunda, Thushara

    2016-04-01

    Rising human demand and climatic variability have created greater uncertainty regarding global food trade and its effects on the food security of nations. To reduce reliance on imported food, many countries have focused on increasing their domestic food production in recent years. With clear goals for the complete self-sufficiency of rice production, Sri Lanka provides an ideal case study for examining the projected growth in domestic rice supply, how this compares to future national demand, and what the associated impacts from water and fertilizer demands may be. Using national rice statistics and estimates of intensification, this study finds that improvements in rice production can feed 25.3 million Sri Lankans (compared to a projected population of 23.8 million people) by 2050. However, to achieve this growth, consumptive water use and nitrogen fertilizer application may need to increase by as much as 69 and 23 %, respectively. This assessment demonstrates that targets for maintaining self-sufficiency should better incorporate avenues for improving resource use efficiency. PMID:26474766

  6. The role of natural disaster in individual and relational adjustment in Sri Lankan mothers following the 2004 tsunami.

    PubMed

    Banford, Alyssa; Ivey, David C; Wickrama, Thulitha; Fischer, Judith; Prouty, Anne; Smith, Douglas

    2016-01-01

    The purpose of this study is to examine the associations between maternal mental health distress symptoms, including depression and post-traumatic stress disorder, the extent to which the presence of a child's disaster-related physical health problem(s) have interfered with daily functioning, and family cohesion over time among Sri Lankan mothers who survived the tsunami on 26 December 2004. Study variables were measured using a self-report questionnaire administered approximately four months after the event and three years later in summer 2008. Univariate, bivariate, and multivariate analyses were conducted. Path analysis was employed to assess the relationships between the key variables over time and the correlations in the study variables at each time point. Among other findings, the results of the path analysis indicated that post-traumatic stress symptom distress four months after the disaster significantly predicted variance in family cohesion three years later. Clinical and empirical research implications are presented and discussed. PMID:26272224

  7. Oral diuretic activity of hot water infusion of Sri Lankan black tea (Camellia sinensis L.) in rats

    PubMed Central

    Abeywickrama, K. R. W.; Ratnasooriya, W. D.; Amarakoon, A. M. T.

    2010-01-01

    Background: Black tea [Camellia sinensis (L.) O. Kuntze (family: Theaceae)] has been used by Sri Lankan traditional practitioners to promote diuresis. However, the type and grade of tea is not specified. Materials and Methods: This study investigates the diuretic activity of black tea infusion (BTI) in rats using Broken Orange Pekoe Fannings (BOPF) grade from major agroclimatic elevations: high-, mid-, and low-grown. Different concentrations of BTI, furosemide (positive control), and water (vehicle) were orally administered to starved (18 h) male rats (n = 9/group), then hydrated. Acute and chronic (28 days) diuretic activities were assessed by measuring cumulative urine output at hourly intervals for 6 h. Electrolyte levels (Na+, K+, Ca2+, H+, Cl−, HCO3−), pH, osmolarity of urine, and glomerular filtration rate (GFR) of treated rats were determined. Results: Administration of BTI induced a significant (P < 0.05) and dose-dependent diuretic activity, which varied with the tea produced in different agroclimatic elevations. Diuretic activity had a rapid onset (1st h), peaked at 2nd h and maintained up to 4th h (except the low dose). Furthermore, there was a dose-dependent increase in micturition frequency, which peaked at 2nd h. A close association between the caffeine content of tea and diuretic activity was evident. BTI-induced diuresis was accompanied with an increased urine Na+ level and GFR. The diuretic activity of BTI was mediated via multiple mechanisms: inhibition of both aldosterone secretion (with increased Na+/K+ ratio) and carbonic anhydrase [with decreased Cl−/(Na+ + K+) ratio] and via thiazide type of diuretic action (evaluated with increased Na+/Cl− ratio). Conclusion: The Sri Lankan BOPF grade black tea possesses mild oral diuretic activity whose efficacy differs with the agroclimatic elevation of production. Furthermore, it supports the traditional claim that the black tea acts as a diuretic. PMID:21120027

  8. Development of the Sri Lankan Early Teenagers' Violence Inventory: An Instrument to Measure Peer Violence in Schools

    PubMed Central

    Seneviratne, Rohini; Østbye, Truls; Lynch, Catherine; Sandøy, Ingvild Fossgard

    2014-01-01

    This study was designed to develop an inventory to measure peer violence among early teens (13–15 years of age) in schools in Sri Lanka. Development of SLETVI was carried out in two phases. In phase I, development of an operational definition for peer violence, identification, and finalizing violent acts for inventory was done by a combination of qualitative methods: a comprehensive literature review, focus group discussions among 13–15-year-old adolescents, their teachers and parents, and consultative meetings with experts in the field. Inventory was then pretested. In phase II, elaboration of SLETVI was carried out by administering it to a sample of 1700 adolescents (13–15 years old). Exploratory factor analysis using principal component analysis was performed separately for experiences of victimization and perpetration. Test-retest reliability of SLETVI was assessed. SLETVI included 37 items in three factors: “less severe violence,” “severe physical,” and “severe relational” violence. Combined use of qualitative and quantitative methods enabled development of a culturally valid and reliable operational inventory to assess early teenagers' peer violence in Sri Lankan and other South Asian schools. PMID:25061607

  9. Development of the Sri Lankan early teenagers' violence inventory: an instrument to measure peer violence in schools.

    PubMed

    Wijeratne, Monika; Seneviratne, Rohini; Gunawardena, Nalika; Østbye, Truls; Lynch, Catherine; Sandøy, Ingvild Fossgard

    2014-01-01

    This study was designed to develop an inventory to measure peer violence among early teens (13-15 years of age) in schools in Sri Lanka. Development of SLETVI was carried out in two phases. In phase I, development of an operational definition for peer violence, identification, and finalizing violent acts for inventory was done by a combination of qualitative methods: a comprehensive literature review, focus group discussions among 13-15-year-old adolescents, their teachers and parents, and consultative meetings with experts in the field. Inventory was then pretested. In phase II, elaboration of SLETVI was carried out by administering it to a sample of 1700 adolescents (13-15 years old). Exploratory factor analysis using principal component analysis was performed separately for experiences of victimization and perpetration. Test-retest reliability of SLETVI was assessed. SLETVI included 37 items in three factors: "less severe violence," "severe physical," and "severe relational" violence. Combined use of qualitative and quantitative methods enabled development of a culturally valid and reliable operational inventory to assess early teenagers' peer violence in Sri Lankan and other South Asian schools. PMID:25061607

  10. Agricultural adaptation to water scarcity in the Sri Lankan dry zone: A comparison of two water managment regimes

    NASA Astrophysics Data System (ADS)

    Burchfield, E. K.

    2014-12-01

    The island nation of Sri Lanka is divided into two agro-climatic zones: the southwestern wet zone and the northeastern dry zone. The dry zone is exposed to drought-like conditions for several months each year. Due to the sporadic nature of rainfall, dry zone livelihoods depend on the successful storage, capture, and distribution of water. Traditionally, water has been captured in rain-fed tanks and distributed through a system of dug canals. Recently, the Sri Lankan government has diverted the waters of the nation's largest river through a system of centrally managed reservoirs and canals and resettled farmers to cultivate this newly irrigated land. This study uses remotely sensed MODIS and LANDSAT imagery to compare vegetation health and cropping patterns in these distinct water management regimes under different conditions of water scarcity. Of particular interest are the socioeconomic, infrastructural, and institutional factors that affect cropping patterns, including field position, water storage capacity, and control of water resources. Results suggest that under known conditions of water scarcity, farmers cultivate other field crops in lieu of paddy. Cultivation changes depend to a large extent on the institutional distance between water users and water managers as well as the fragmentation of water resources within the system.

  11. Rates and Psychological Effects of Exposure to Family Violence among Sri Lankan University Students

    ERIC Educational Resources Information Center

    Haj-Yahia, Muhammad M.; de Zoysa, Piyanjli

    2008-01-01

    Objectives: The study had two objectives: to examine the rates of exposure to family violence among students in a non-Western society, with Sri Lanka as a case study and to examine the psychological effects of their exposure. Method: Four hundred seventy six medical students in Sri Lanka were surveyed. A self-administered questionnaire was…

  12. DIABRISK - SL Prevention of cardio-metabolic disease with life style modification in young urban Sri Lankan's - study protocol for a randomized controlled trial

    PubMed Central

    2011-01-01

    Background Urban South-Asian's are predisposed to early onset of type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). There is an urgent need for country specific primary prevention strategies to address the growing burden of cardio-metabolic disease in this population. The aim of this clinical trial is to evaluate whether intensive (3-monthly) lifestyle modification advice is superior to a less-intensive (12 monthly; control group) lifestyle modification advice on a primary composite cardio-metabolic end point in 'at risk' urban subjects aged between 5-40 years. Methods/Design This is an open randomised controlled parallel group clinical trial performed at a single centre in Colombo, Sri-Lanka. A cluster sampling strategy was used to select a large representative sample of subjects aged between 5-40 years at high risk of T2DM and CVD for the intervention study. We have screened 23,298 (males 47% females 53%) healthy subjects for four risk factors: obesity, elevated waist circumference, family history of diabetes and physical inactivity, using a questionnaire and anthropometry. Those with two or more risk-factors were recruited to the intervention trial. We aim to recruit 4600 subjects for the intervention trial. The primary composite cardio-metabolic end point is; new onset T2DM, impaired glucose tolerance, impaired fasting glycaemia, new onset hypertension and albuminuria, following 5 years of intervention. The effect of the intervention on pre-specified secondary endpoints will also be evaluated. The study will be conducted according to good clinical and ethical practice, data analysis and reporting guidelines. Discussion DIABRISK-SL is a large population based trial to evaluate the prevalence of diabetes, pre-diabetes and cardio-metabolic risk factors among young urban Sri-Lankans and the effect of a primary prevention strategy on cardio-metabolic disease end points. This work will enable country specific and regional cardio-metabolic risk scores

  13. Sri Lankan Case Study on Public/Private Participation in the Promotion of Wind Energy

    NASA Astrophysics Data System (ADS)

    Robinson, Rod; Thanthilage, Rohitha

    2007-10-01

    Micro wind power systems are one of the most appropriate and comparatively economical renewable energy sources to meet the off-grid energy needs of Sri Lanka. To penetrate the target markets and intended beneficiaries of Sri Lanka, it requires sound demonstrations to prove its technical, financial and or economic viability. This paper, presents a case study of a successful wind powered rural electrification project and the establishment of a revolving fund with public/private participation.

  14. A study of genetic polymorphisms in mitochondrial DNA hypervariable regions I and II of the five major ethnic groups and Vedda population in Sri Lanka.

    PubMed

    Ranasinghe, Ruwandi; Tennekoon, Kamani H; Karunanayake, Eric H; Lembring, Maria; Allen, Marie

    2015-11-01

    Diversity of the hypervariable regions (HV) I and II of the mitochondrial genome was studied in maternally unrelated Sri Lankans (N=202) from six ethnic groups (i.e.: Sinhalese, Sri Lankan Tamil, Muslim, Malay, Indian Tamil and Vedda). DNA was extracted from blood and buccal swabs and HVI and HVII regions were PCR amplified and sequenced. Resulting sequences were aligned and edited between 16024-16365 and 73-340 regions and compared with revised Cambridge reference sequences (rCRS). One hundred and thirty-five unique haplotypes and 22 shared haplotypes were observed. A total of 145 polymorphic sites and 158 polymorphisms were observed. Hypervariable region I showed a higher polymorphic variation than hypervariable region II. Nucleotide diversities were quite low and similar for all ethnicities apart from a slightly higher value for Indian Tamils and a much lower value for the Vedda population compared to the other groups. When the total population was considered South Asian (Indian) haplogroups were predominant, but there were differences in the distribution of phylo-geographical haplogroups between ethnic groups. Sinhalese, Sri Lankan Tamil and Vedda populations had a considerable presence of West Eurasian haplogroups. About 2/3rd of the Vedda population comprised of macro-haplogroup N or its subclades R and U, whereas macro-haplogroup M was predominant in all other populations. The Vedda population clustered separately from other groups and Sri Lankan Tamils showed a closer genetic affiliation to Sinhalese than to Indian Tamils. Thus this study provides useful information for forensic analysis and anthropological studies of Sri Lankans. PMID:26065620

  15. Cranial arterial pattern of the Sri Lankan spotted chevrotain, Moschiola memmina, and comparative basicranial osteology of the Tragulidae

    PubMed Central

    2015-01-01

    The cranial arterial pattern of artiodactyls deviates significantly from the typical mammalian pattern. One of the most striking atypical features is the rete mirabile epidurale: a subdural arterial meshwork that functionally and anatomically replaces the arteria carotis interna. This meshwork facilitates an exceptional ability to cool the brain, and was thought to be present in all artiodactyls. Recent research, however, has found that species of mouse deer (Artiodactyla: Tragulidae) endemic to the Malay Archipelago possess a complete a. carotis interna instead of a rete mirabile epidurale. As tragulids are the sister group to pecoran ruminants, the lack of a rete mirabile epidurale in these species raises intriguing evolutionary questions about the origin and nature of artiodactyl thermoregulatory cranial vasculature. In this study, cranial arterial patterns are documented for the remaining species within the Tragulidae. Radiopaque latex vascular injection, computed tomography (CT-scanning), and digital 3-dimensional anatomical reconstruction are used to image the cranial arteries of a Sri Lankan spotted chevrotain, Moschiola meminna. Sites of hard and soft tissue interaction were identified, and these osteological correlates were then sought in nine skulls representative of the remaining tragulid species. Both hard and soft tissue surveys confirm that the presence of an a. carotis interna is the common condition for tragulids. Moreover, the use of a 3-D, radiographic anatomical imaging technique enabled identification of a carotico-maxillary anastomosis that may have implications for the evolution of the artiodactyl rete mirabile epidurale. PMID:26644983

  16. Attitude Towards Health Information Privacy and Electronic Health Records Among Urban Sri Lankan Adults.

    PubMed

    Tissera, Shaluni R; Silva, S N

    2016-01-01

    Sri Lanka is planning to move towards an Electronic Health Record (EHR) system. This research argues that the public preparedness should be considered in order to implement a functioning and an effective EHR system in a country. When asked about how concerned the participants were about the security of their health records, 40.5% stated they were concerned and 38.8% were very concerned. They were asked to rate the 'level of trust' they have on health institutes in Sri Lanka on a scale from 1 to 10 (1 lowest level of trust and 10 highest), 66.1% rated at level 5 or less. PMID:27332453

  17. The health behavior of Sri Lankan Buddhist nuns with type 2 diabetes: duty, devotion, and detachment.

    PubMed

    Wijesinghe, Sunny; Mendelson, Cindy

    2013-12-01

    Sri Lanka has experienced an increase in the rate of type 2 diabetes. Selfmanagement of diabetes among Sri Lanka's Buddhist nuns, who depend on food donations and limit physical activity in accord with the monastic code of conduct, presents unique challenges and has not been previously studied. The purpose of this focused ethnographic study of 10 Buddhist nuns was to understand how they managed their illness within the restrictions on diet and physical activity. Three themes-duty, devotion, and detachment-explained and described their health behavior regarding type 2 diabetes within the context of their daily routines and obligations. PMID:22395758

  18. Z-Score Demystified: A Critical Analysis of the Sri Lankan University Admission Policy

    ERIC Educational Resources Information Center

    Warnapala, Yajni; Silva, Karishma

    2011-01-01

    In the year 2001, the University Grants Commission of Sri Lanka successfully appealed to change the method of determining the cut-off scores for university admissions from raw scores to standardized z-scores. This standardization allegedly eliminated the discrepancy caused due to the assumption of equal difficulty levels across all subjects. This…

  19. Developing Government Policies for Distance Education: Lessons Learnt from Two Sri Lankan Case Studies

    ERIC Educational Resources Information Center

    Liyanagunawardena, Tharindu Rekha; Adams, Andrew A.; Rassool, Naz; Williams, Shirley A.

    2014-01-01

    Education, especially higher education, is considered vital for maintaining national and individual competitiveness in the global knowledge economy. Following the introduction of its "Free Education Policy" as early as 1947, Sri Lanka is now the best performer in basic education in the South Asian region, with a remarkable record in…

  20. Sri Lankan National Melioidosis Surveillance Program Uncovers a Nationwide Distribution of Invasive Melioidosis.

    PubMed

    Corea, Enoka M; Merritt, Adam J; Ler, Yi-Horng; Thevanesam, Vasanthi; Inglis, Timothy J J

    2016-02-01

    The epidemiologic status of melioidosis in Sri Lanka was unclear from the few previous case reports. We established laboratory support for a case definition and started a nationwide case-finding study. Suspected Burkholderia pseudomallei isolates were collated, identified by polymerase chain reaction assay, referred for Matrix Assisted Laser Desorption Ionization-Time of Flight analysis and multilocus sequence typing (MLST), and named according to the international MLST database. Between 2006 and early 2014, there were 32 patients with culture-confirmed melioidosis with an increasing annual total and a falling fatality rate. Patients were predominantly from rural communities, diabetic, and male. The major clinical presentations were sepsis, pneumonia, soft tissue and joint infections, and other focal infection. Burkholderia pseudomallei isolates came from all parts of Sri Lanka except the Sabaragamuwa Province, the south central hill country, and parts of northern Sri Lanka. Bacterial isolates belonged to 18 multilocus sequence types, one of which (ST 1137) was associated with septicemia and a single-organ focus (Fisher's exact, P = 0.004). Melioidosis is an established endemic infection throughout Sri Lanka, and is caused by multiple genotypes of B. pseudomallei, which form a distinct geographic group based upon related sequence types (BURST) cluster at the junction of the southeast Asian and Australasian clades. PMID:26621560

  1. Sri Lankan livelihoods after the tsunami: searching for entrepreneurs, unveiling relations of power.

    PubMed

    Kapadia, Kamal

    2015-01-01

    This paper analyses the performance of aid-funded livelihoods recovery efforts in Sri Lanka following the Indian Ocean tsunami of 26 December 2004, with special attention paid to the effects on the rural poor. It argues that successful livelihoods recovery was hampered by an excessive focus by aid agencies on entrepreneurs and entrepreneurship, and by the lack of a politically informed understanding of the economy. Based on ethnographic and survey-based research, the study demonstrates that the category of 'entrepreneur' is misleading for large parts of the economy. Indeed, the desire to build an entrepreneurial economy actually hampered successful livelihoods recovery in Sri Lanka and, in some cases, reinforced inequitable relations of power. The paper concludes that for livelihoods recovery programmes to be effective, they must be founded on an understanding of the relations of power that constitute the economy; these relations operate across scales, and are historically and geographically specific. PMID:25231676

  2. Suffering, frustration, and anger: class, gender and history in Sri Lankan suicide stories.

    PubMed

    Widger, Tom

    2012-06-01

    This paper explores competing stories of suffering, frustration and anger that shape the performance and reception of suicidal behaviours in contemporary Sri Lanka. Drawing from the results of 21 months of ethnographic fieldwork, I show how suicidal acts fit within broader narratives of class and gender experience and expression that draw from contemporary and historical 'folk' and 'state' discourses. Debates over whether suffering, frustration and anger are legitimate socio-effective states to exhibit come to determine the kinds of claims and counter-claims that suicidal people on the one hand, and those charged with their treatment and management on the other, can make with regard to the efficacy of suicide as a means of social action. Through such debates-not only what it means to be suicidal in Sri Lanka but also what it means to be middle class or working class, male or female, etc. are made and remade anew. PMID:22392638

  3. On parrots and thorns: Sri Lankan perspective on genetics, science and personhood.

    PubMed

    Simpson, Bob

    2007-03-01

    This paper addresses the issue of how the scientific discourse of genetics is expressed in local idioms. The examples used are taken from fieldwork conducted in Sri Lanka and relate principally to Sinhala Buddhist attempts to socialise 'big science.' The paper explores idioms of both nature and nurture in local imagery and narratives and draws attention to the rhetorical dimensions of genetic discourses when used in context. The article concludes with a preliminary attempt to identify the ways in which explanations of genetic causality are aligned with notions of karma in the explanation of illness and misfortune. PMID:17373131

  4. Resistance to Sri Lankan cassava mosaic virus (SLCMV) in genetically engineered cassava cv. KU50 through RNA silencing.

    PubMed

    Ntui, Valentine Otang; Kong, Kynet; Khan, Raham Sher; Igawa, Tomoko; Janavi, Gnanaguru Janaky; Rabindran, Ramalingam; Nakamura, Ikuo; Mii, Masahiro

    2015-01-01

    Cassava ranks fifth among the starch producing crops of the world, its annual bioethanol yield is higher than for any other crop. Cassava cultivar KU50, the most widely grown cultivar for non-food purposes is susceptible to Sri Lankan cassava mosaic virus (SLCMV). The objective of this work was to engineer resistance to SLCMV by RNA interference (RNAi) in order to increase biomass yield, an important aspect for bioethanol production. Here, we produced transgenic KU50 lines expressing dsRNA homologous to the region between the AV2 and AV1 of DNA A of SLCMV. High level expression of dsRNA of SLCMV did not induce any growth abnormality in the transgenic plants. Transgenic lines displayed high levels of resistance to SLCMV compared to the wild-type plants and no virus load could be detected in uninoculated new leaves of the infected resistant lines after PCR amplification and RT-PCR analysis. The agronomic performance of the transgenic lines was unimpaired after inoculation with the virus as the plants presented similar growth when compared to the mock inoculated control plants and revealed no apparent reduction in the amount and weight of tubers produced. We show that the resistance is correlated with post-transcriptional gene silencing because of the production of transgene specific siRNA. The results demonstrate that transgenic lines exhibited high levels of resistance to SLCMV. This resistance coupled with the desirable yield components in the transgenic lines makes them better candidates for exploitation in the production of biomass as well as bioethanol. PMID:25901740

  5. Efficacy of Indian polyvalent snake antivenoms against Sri Lankan snake venoms: lethality studies or clinically focussed in vitro studies.

    PubMed

    Maduwage, Kalana; Silva, Anjana; O'Leary, Margaret A; Hodgson, Wayne C; Isbister, Geoffrey K

    2016-01-01

    In vitro antivenom efficacy studies were compared to rodent lethality studies to test two Indian snake antivenoms (VINS and BHARAT) against four Sri Lankan snakes. In vitro efficacy was tested at venom concentrations consistent with human envenoming. Efficacy was compared statistically for one batch from each manufacturer where multiple vials were available. In binding studies EC50 for all VINS antivenoms were less than BHARAT for D. russelii [553 μg/mL vs. 1371 μg/mL;p = 0.016), but were greater for VINS antivenoms compared to BHARAT for N. naja [336 μg/mL vs. 70 μg/mL;p < 0.0001]. EC50 of both antivenoms was only slighty different for E. carinatus and B. caeruleus. For procoagulant activity neutralisation, the EC50 was lower for VINS compared to BHARAT - 60 μg/mL vs. 176 μg/mL (p < 0.0001) for Russell's viper and 357 μg/mL vs. 6906μg/mL (p < 0.0001) for Saw-scaled viper. Only VINS antivenom neutralized in vitro neurotoxicity of krait venom. Both antivenoms partially neutralized cobra and didn't neutralize Russell's viper neurotoxicity. Lethality studies found no statistically significant difference in ED50 values between VINS and BHARAT antivenoms. VINS antivenoms appeared superior to BHARAT at concentrations equivalent to administering 10 vials antivenom, based on binding and neutralisation studies. Lethality studies were inconsistent suggesting rodent death may not measure relevant efficacy outcomes in humans. PMID:27231196

  6. Efficacy of Indian polyvalent snake antivenoms against Sri Lankan snake venoms: lethality studies or clinically focussed in vitro studies

    PubMed Central

    Maduwage, Kalana; Silva, Anjana; O’Leary, Margaret A.; Hodgson, Wayne C.; Isbister, Geoffrey K.

    2016-01-01

    In vitro antivenom efficacy studies were compared to rodent lethality studies to test two Indian snake antivenoms (VINS and BHARAT) against four Sri Lankan snakes. In vitro efficacy was tested at venom concentrations consistent with human envenoming. Efficacy was compared statistically for one batch from each manufacturer where multiple vials were available. In binding studies EC50 for all VINS antivenoms were less than BHARAT for D. russelii [553 μg/mL vs. 1371 μg/mL;p = 0.016), but were greater for VINS antivenoms compared to BHARAT for N. naja [336 μg/mL vs. 70 μg/mL;p < 0.0001]. EC50 of both antivenoms was only slighty different for E. carinatus and B. caeruleus. For procoagulant activity neutralisation, the EC50 was lower for VINS compared to BHARAT - 60 μg/mL vs. 176 μg/mL (p < 0.0001) for Russell’s viper and 357 μg/mL vs. 6906μg/mL (p < 0.0001) for Saw-scaled viper. Only VINS antivenom neutralized in vitro neurotoxicity of krait venom. Both antivenoms partially neutralized cobra and didn’t neutralize Russell’s viper neurotoxicity. Lethality studies found no statistically significant difference in ED50 values between VINS and BHARAT antivenoms. VINS antivenoms appeared superior to BHARAT at concentrations equivalent to administering 10 vials antivenom, based on binding and neutralisation studies. Lethality studies were inconsistent suggesting rodent death may not measure relevant efficacy outcomes in humans. PMID:27231196

  7. Resistance to Sri Lankan Cassava Mosaic Virus (SLCMV) in Genetically Engineered Cassava cv. KU50 through RNA Silencing

    PubMed Central

    Ntui, Valentine Otang; Kong, Kynet; Khan, Raham Sher; Igawa, Tomoko; Janavi, Gnanaguru Janaky; Rabindran, Ramalingam; Nakamura, Ikuo; Mii, Masahiro

    2015-01-01

    Cassava ranks fifth among the starch producing crops of the world, its annual bioethanol yield is higher than for any other crop. Cassava cultivar KU50, the most widely grown cultivar for non-food purposes is susceptible to Sri Lankan cassava mosaic virus (SLCMV). The objective of this work was to engineer resistance to SLCMV by RNA interference (RNAi) in order to increase biomass yield, an important aspect for bioethanol production. Here, we produced transgenic KU50 lines expressing dsRNA homologous to the region between the AV2 and AV1 of DNA A of SLCMV. High level expression of dsRNA of SLCMV did not induce any growth abnormality in the transgenic plants. Transgenic lines displayed high levels of resistance to SLCMV compared to the wild-type plants and no virus load could be detected in uninoculated new leaves of the infected resistant lines after PCR amplification and RT-PCR analysis. The agronomic performance of the transgenic lines was unimpaired after inoculation with the virus as the plants presented similar growth when compared to the mock inoculated control plants and revealed no apparent reduction in the amount and weight of tubers produced. We show that the resistance is correlated with post-transcriptional gene silencing because of the production of transgene specific siRNA. The results demonstrate that transgenic lines exhibited high levels of resistance to SLCMV. This resistance coupled with the desirable yield components in the transgenic lines makes them better candidates for exploitation in the production of biomass as well as bioethanol. PMID:25901740

  8. Effects of the Sri Lankan medicinal plant, Salacia reticulata, in rheumatoid arthritis.

    PubMed

    Sekiguchi, Yuusuke; Mano, Hiroshi; Nakatani, Sachie; Shimizu, Jun; Wada, Masahiro

    2010-03-01

    Salacia reticulata is a native plant of Sri Lanka. In the traditional medicine of Sri Lanka and India, Salacia reticulata bark is considered orally effective in the treatment of rheumatism, gonorrhea, skin disease and diabetes. We have investigated, both in vivo and in vitro, whether the leaf of Salacia reticulata (SRL) can ameliorate collagen antibody-induced arthritis (CAIA) in mice as the rheumatoid arthritis (RA) model. The mice were fed a lard containing chow diet (AIN-93G) or the same diet containing 1% (w/w) SRL powder. All mice were bred for 23 days. On day 7 or 14 after LPS injection, mice were killed, and tissue and blood samples were collected. Histological analysis was performed, and serum levels of inflammatory mediators and the mRNA levels of inflammation-related genes and osteoclast-related genes were measured. SRL treatment ameliorated the rapid initial paw swelling, inflammatory cells infiltration, skeletal tissues damage, osteoclast activation and the mRNA levels for osteoclast-related genes compared with the CAIA mice. However, the serum and mRNA levels of inflammatory mediators did not differ between the CAIA mice and the SRL-treated mice. SRL might reduce the inflammatory cells induction and skeletal tissue degradation by CAIA by the regulating osteoclastogenesis. PMID:19727885

  9. Awareness and perceptions on prevention, first aid and treatment of snakebites among Sri Lankan farmers: a knowledge practice mismatch?

    PubMed Central

    2014-01-01

    Background Snakebite is a global health problem associated with high morbidity and mortality. In Sri Lanka, snakebite is mainly an occupational health hazard associated with farming. Understanding awareness and perceptions in risk populations on the preventive measures, first aid and treatment for snakebite becomes pivotal in designing snakebite prevention and control programs. Using an investigator assisted self completed questionnaire, we assessed the awareness and perceptions of 176 part-time and full-time, Chena and paddy farmers from three dry zone districts of Sri Lanka where agriculture is the main economic activity. Findings High percentages of the participants were aware of practices that minimize snakebites in houses and outside, available treatments and most of the recommended first aid measures. Western medical treatment was preferred by the vast majority of the farmers over the traditional treatment. Conclusion Some of the protective measures that the farmers were aware of are not practiced generally in Sri Lanka, suggesting a knowledge-practice mismatch. We suggest studies to understand the effects of socioeconomic and cultural determinants on snakebite prevention in Sri Lanka. PMID:24847375

  10. Mitochondrial DNA-based analysis of genetic variation and relatedness among Sri Lankan indigenous chickens and the Ceylon junglefowl (Gallus lafayetti).

    PubMed

    Silva, P; Guan, X; Ho-Shing, O; Jones, J; Xu, J; Hui, D; Notter, D; Smith, E

    2009-02-01

    Indigenous chickens (IC) in developing countries provide a useful resource to detect novel genes in mitochondrial and nuclear genomes. Here, we investigated the level of genetic diversity in IC from five distinct regions of Sri Lanka using a PCR-based resequencing method. In addition, we investigated the relatedness of IC to different species of junglefowls including Ceylon (CJF; Gallus lafayetti), a subspecies that is endemic to Sri Lanka, green (Gallus varius), grey (Gallus sonneratii) and red (Gallus gallus) junglefowls. A total of 140 birds including eight CJF were used to screen the control region of the mitochondrial DNA sequence for single nucleotide polymorphisms (SNPs) and other variants. We detected and validated 44 SNPs, which formed 42 haplotypes and six haplogroups in IC. The SNPs observed in the CJF were distinct and the D-loop appeared to be missing a 62-bp segment found in IC and the red junglefowl. Among the six haplogroups of IC, only one was region-specific. Estimates of haplotype and nucleotide diversities ranged from 0.901 to 0.965 and from 0.011 to 0.013 respectively, and genetic divergence was generally low. Further, variation among individuals within regions accounted for 92% of the total molecular variation among birds. The Sri Lankan IC were more closely related to red and grey junglefowls than to CJF, indicating multiple origins. The molecular information on genetic diversity revealed in our study may be useful in developing genetic improvement and conservation strategies to better utilize indigenous Sri Lankan chicken resources. PMID:18945292

  11. Oral Health Status of the Veddas-Sri Lankan Indigenous People.

    PubMed

    Jayashantha, Pradeep; Johnson, Newell W

    2016-01-01

    Sri Lanka's Veddas/Vanniya-laeto, are a small Indigenous group today with little information on their oral health status. This report is to provide an overview on oral health status of Veddas. Oral health status was recorded by the principal investigator after obtaining consent, using World Health Organization criteria, at an initial screening point before sending the person for any necessary treatment. Total participants were 194: 78% were males>35 years. Mean decayed, missing, filled teeth was 0.9 and 3% had pockets <3.5mm. Three had oral potentially malignant disorders (OPMDs), while three were treated for oral cancer. While the prevalence of dental caries and periodontal conditions was low, oral cancer and OPMDs is a serious concern. The Veddas have a culturally specific health system based on herbal medicinal knowledge. Thus, it is challenging to introduce and implement a preventive and curative oral health care system that would be culturally acceptable to this community. PMID:26853207

  12. The interrelationship between dengue incidence and diurnal ranges of temperature and humidity in a Sri Lankan city and its potential applications

    PubMed Central

    Ehelepola, N. D. B.; Ariyaratne, Kusalika

    2015-01-01

    Background Temperature, humidity, and other weather variables influence dengue transmission. Published studies show how the diurnal fluctuations of temperature around different mean temperatures influence dengue transmission. There are no published studies about the correlation between diurnal range of humidity and dengue transmission. Objective The goals of this study were to determine the correlation between dengue incidence and diurnal fluctuations of temperature and humidity in the Sri Lankan city of Kandy and to explore the possibilities of using that information for better control of dengue. Design We calculated the weekly dengue incidence in Kandy during the period 2003–2012, after collecting data on all of the reported dengue patients and estimated midyear populations. Data on daily maximum and minimum temperatures and night-time and daytime humidity were obtained from two weather stations, averaged, and converted into weekly data. The number of days per week with a diurnal temperature range (DTR) of >10°C and <10°C and the number of days per week with a diurnal humidity range (DHR) of >20 and <15% were calculated. Wavelet time series analysis was performed to determine the correlation between dengue incidence and diurnal ranges of temperature and humidity. Results There were negative correlations between dengue incidence and a DTR >10°C and a DHR >20% with 3.3-week and 4-week lag periods, respectively. Additionally, positive correlations between dengue incidence and a DTR <10°C and a DHR <15% with 3- and 4-week lag periods, respectively, were discovered. Conclusions These findings are consistent with the results of previous entomological studies and theoretical models of DTR and dengue transmission correlation. It is important to conduct similar studies on diurnal fluctuations of humidity in the future. We suggest ways and means to use this information for local dengue control and to mitigate the potential effects of the ongoing global reduction of

  13. Glycaemic indices of three Sri Lankan wheat bread varieties and a bread-lentil meal.

    PubMed

    Hettiaratchi, U P K; Ekanayake, S; Welihinda, J

    2009-01-01

    The glycaemic index (GI) concept ranks individual foods and mixed meals according to the blood glucose response. Low-GI foods with a slow and prolonged glycaemic response are beneficial for diabetic people, and several advantages have been suggested also for non-diabetic individuals. The recent investigations imply an increasing prevalence of diabetes mellitus in Sri Lanka. Thus, the present study was designed primarily to determine the glycaemic indices of some bread varieties in Sri Lanka as bread has become a staple diet among most of the urban people. A second objective was to observe the effects of macronutrients and physicochemical properties of starch on GI. Glycaemic responses were estimated according to FAO/WHO guidelines and both glucose and white bread were used as standards. Non-diabetic individuals aged 22-30 years (n=10) participated in the study. The test meals included white sliced bread, wholemeal bread, ordinary white bread and a mixed meal of wholemeal bread with lentil curry. The GI values (+/-standard error of the mean) of the meals were 77+/-6, 77+/-6, 80+/-4, 61+/-6, respectively (with glucose as the standard). The GI values of the bread varieties or the meal did not differ significantly (P >0.05). However, the meal can be categorized as a medium-GI food while the other bread varieties belong to the high-GI food group. A significant negative correlation was obtained with protein (P=0.042) and fat (P=0.039) contents of the food items and GI. Although the GI values of the foods are not significantly different, the inclusion of lentils caused the GI to decrease from a high-GI category to a medium-GI category. According to the present study, a ratio of 1.36 can be used to interconvert the GI values obtained with the two standards. PMID:19418328

  14. Genetic Variation of Flavonols Quercetin, Myricetin, and Kaempferol in the Sri Lankan Tea (Camellia sinensis L.) and Their Health-Promoting Aspects

    PubMed Central

    Jeganathan, Brasathe; Kottawa-Arachchi, J. Dananjaya; Ranatunga, Mahasen A. B.; Abeysinghe, I. Sarath B.; Gunasekare, M. T. Kumudini; Bandara, B. M. Ratnayake

    2016-01-01

    Flavonol glycosides in tea leaves have been quantified as aglycones, quercetin, myricetin, and kaempferol. Occurrence of the said compounds was reported in fruits and vegetable for a long time in association with the antioxidant potential. However, data on flavonols in tea were scanty and, hence, this study aims to envisage the flavonol content in a representative pool of accessions present in the Sri Lankan tea germplasm. Significant amounts of myricetin, quercetin, and kaempferol have been detected in the beverage type tea accessions of the Sri Lankan tea germplasm. This study also revealed that tea is a good source of flavonol glycosides. The Camellia sinensis var. sinensis showed higher content of myricetin, quercetin, and total flavonols than var. assamica and ssp. lasiocalyx. Therefore flavonols and their glycosides can potentially be used in chemotaxonomic studies of tea germplasm. The nonbeverage type cultivars, especially Camellia rosaflora and Camellia japonica Red along with the exotic accessions resembling China type, could be useful in future germplasm studies because they are rich sources of flavonols, namely, quercetin and kaempferol, which are potent antioxidants. The flavonol profiles can be effectively used in choosing parents in tea breeding programmes to generate progenies with a wide range of flavonol glycosides. PMID:27366737

  15. First reported case of systemic envenoming by the Sri Lankan keelback (Balanophis ceylonensis).

    PubMed

    Fernando, W K B K M; Kularatne, S A M; Wathudura, S P K; de Silva, A; Mori, A; Mahaulpatha, D

    2015-01-01

    Envenoming by colubrid snakes is rarely reported. However, some colubrid snakes (e.g. Rhabdophis tigrinus and Rhabdophis subminiatus) have caused severe systemic envenoming. We report here the first case of a bite with systemic envenoming by Balanophis ceylonensis, an opisthoglyphous natricine colubrid, in Sri Lanka. A 33-year-old healthy male field biologist was bitten while handling the snake for photography. Within 5 min of the bite on the dorsum of the right hand, he reported severe occipital headache, photophobia, chills and transient loss of consciousness. He vomited blood-stained gastric contents and bled from venepuncture sites. He had a markedly elevated INR and positive D-dimer test suggestive of significant coagulopathy that was treated with infusions of fresh frozen plasma. He recovered and left hospital after 96 h and subsequent investigations, including electroencephalogram, were normal. We conclude that B. ceylonensis should be regarded as a medically significant venomous snake. This case highlights the need for further studies of the oral secretions (venoms) of colubrid snakes. PMID:25447769

  16. Farm level and geographic predictors of antibiotic use in Sri Lankan shrimp farms.

    PubMed

    Munasinghe, Nalaka; Stephen, Craig; Robertson, Colin; Abeynayake, Preeni

    2012-03-01

    Black tiger shrimp Penaeus monodon farming is important for Sri Lanka's rural development plans. Consumer confidence is critical for the development and maintenance of export and domestic shrimp markets. Public concern about the use of antimicrobial drugs and chemicals on shrimp farms, however, could threaten market access. We sought to identify high-risk areas and farm-level risk factors for antimicrobial use to inform the core messages and strategic placement of extension programs to help farmers develop best management practices for antimicrobial use. We undertook a survey of 603 operating farms within the Puttalam district over 42 weeks. Lower stocking density and early harvest were associated with a lower risk of antimicrobial use, whereas standard management practices, including water treatment, feed supplements, probiotic use, pond fertilizing, disinfectant use, and pesticide use, were associated with increased risk. Spatial cluster detection found three significant clusters of antimicrobial-using farms. Antimicrobials were more likely to be used in areas with lower farm density. Some of our counterintuitive findings are discussed from a socioecological perspective. A comprehensive understanding of why antimicrobials are used on shrimp farms requires an evaluation of the physical, epidemiological, and socioeconomic factors. PMID:22779210

  17. Artefactual incised wounds due to postmortem predation by the Sri Lankan water monitor (kabaragoya).

    PubMed

    Gunawardena, Sameera A

    2016-09-01

    Monitor lizards are large reptilian animals mostly seen around water based habitats. Sri Lanka has an endemic water monitor lizard called the kabaragoya (Varanus salvator salvator) which is perhaps the most common large animal scavenger in the country. Scavenging by the kabaragoya can result in postmortem incised injuries which are caused by their sharp pointed claws as they grip or crawl over a dead body. The author presents four cases where these claw marks raised significant medicolegal issues. In one case of a young female they mimicked defense injuries that might be seen in a person that was killed with heavy sharp weapon trauma to the head. In another case, claw marks on the face raised homicidal allegations in an immersion death following intoxication. In a case of suicidal drowning these injuries simulated self-inflicted cuts. The fourth case shows how claw marks complicated the investigation of a dismembered upper limb. Kabaragoya claw marks are mostly seen in decomposed and macerated bodies recovered from water. Injuries are mostly superficial and limited to skin and soft tissues. Bony injuries are not seen. Awareness of the creature's scavenging habits and careful analysis of the appearance and distribution of the injuries is essential to differentiate claw marks from sharp weapon trauma. PMID:27216749

  18. A Focused Ethnographic Study of Sri Lankan Government Field Veterinarians’ Decision Making about Diagnostic Laboratory Submissions and Perceptions of Surveillance

    PubMed Central

    Sawford, Kate; Vollman, Ardene Robinson; Stephen, Craig

    2012-01-01

    The global public health community is facing the challenge of emerging infectious diseases. Historically, the majority of these diseases have arisen from animal populations at lower latitudes where many nations experience marked resource constraints. In order to minimize the impact of future events, surveillance of animal populations will need to enable prompt event detection and response. Many surveillance systems targeting animals rely on veterinarians to submit cases to a diagnostic laboratory or input clinical case data. Therefore understanding veterinarians’ decision-making process that guides laboratory case submission and their perceptions of infectious disease surveillance is foundational to interpreting disease patterns reported by laboratories and engaging veterinarians in surveillance initiatives. A focused ethnographic study was conducted with twelve field veterinary surgeons that participated in a mobile phone-based surveillance pilot project in Sri Lanka. Each participant agreed to an individual in-depth interview that was recorded and later transcribed to enable thematic analysis of the interview content. Results found that field veterinarians in Sri Lanka infrequently submit cases to laboratories – so infrequently that common case selection principles could not be described. Field veterinarians in Sri Lanka have a diagnostic process that operates independently of laboratories. Participants indicated a willingness to take part in surveillance initiatives, though they highlighted a need for incentives that satisfy a range of motivations that vary among field veterinarians. This study has implications for the future of animal health surveillance, including interpretation of disease patterns reported, system design and implementation, and engagement of data providers. PMID:23133542

  19. Genesis of Cr(VI) in Sri Lankan soils and its adsorptive removal by calcined gibbsite

    NASA Astrophysics Data System (ADS)

    Rajapaksha, A. U.; Wijesundara, D. M.; Vithanage, M. S.; Ok, Y. S.

    2012-12-01

    Hexavalent chromium is highly toxic to biota and considered as a priority pollutant. Industrial sources of Cr(VI) include leather tanning, plating, electroplating, anodizing baths, rinse waters, etc. In addition, weathering of ultramafic rocks rich in chromium, such as serpentine, is known to Cr(VI) sources into natural water. The Cr(III) is the most stable in the environment, however, conversion of Cr(III) into Cr(VI) occurs in soil due to presence of naturally occurring minerals such as manganese dioxides. We investigated the amount of Cr(VI) recorded from the soils from anthropogenically and naturally contaminated soils (serpentine soils) in Sri Lanka and the removal efficacy of Cr(VI) by calcined gibbsite (Al oxides). The effect of pH on Cr(VI) adsorption was determined by adjusting the pH in the range of 4-10. In the experiments, the adsorbent concentration was kept at 1 g/l of solution containing 10 mg/l Cr(VI) at 25 0C. Total chromium recorded were around 11,000 mg kg-1 and 6,000 mg kg-1 for serpentine soil and tannery waste-contaminated soil, respectively. Although total Cr was high in the contaminated soils, Cr(VI) concentration was only about 28 mg kg-1 and 210 mg kg-1 in the serpentine and tannery soils, respectively. The calcined gibbsite has maximum adsorption of 85 % around pH 4 and adsorption generally decreased with increase of pH.

  20. Migration of BTEX and phthalates from natural rubber latex balloons obtained from the Sri Lankan market.

    PubMed

    Jayawardena, Imanda; Godakumbura, Pahan I; Prashantha, M A B

    2016-01-01

    The current study evaluates the migration of benzene, toluene, ethylbenzene, xylene (BTEX) and phthalates into artificial saliva from natural rubber latex (NRL) balloons available for sale in Sri Lanka. It was discovered that at least one BTEX compound migrated from almost all the brands. The migration of four phthalates; diethyl phthalate, dibutyl phthalate, di-isobutyl phthalate and butyl benzyl phthalate were also observed. Migratory levels of BTEX and phthalates in most of the balloon brands were above the permissible levels set by the European Union. Assessment of factors affecting the migratory levels indicated migration under active mouthing conditions and migration from the neck region of the balloons were significantly higher. The migratory levels were observed to decrease with storage time, and in certain brands the BTEX levels decreased below the permissible level. One-way ANOVA indicated no significant differences (p ≥ 0.05) in migratory levels of each individual compound within the same brand for both BTEX and phthalates. When compared among different brands, BTEX levels indicated significant differences (p ≤ 0.05), while phthalate levels were observed to not be significantly different (p ≥ 0.05). A significant difference was also observed (p ≤ 0.05) among the migratory levels of compounds under each test condition evaluated as factors affecting the migratory level. Furthermore, the solvent based colorants added to color the latex were found to be the source of BTEX and phthalates in the NRL balloons. PMID:26759759

  1. Monitoring and predicting eutrophication of Sri Lankan inland waters using ASTER satellite data

    NASA Astrophysics Data System (ADS)

    Dahanayaka, D. D. G. L.; Wijeyaratne, M. J. S.; Tonooka, H.; Minato, A.; Ozawa, S.; Perera, B. D. C.

    2014-10-01

    This study focused on determining the past changes and predicting the future trends in eutrophication of the Bolgoda North lake, Sri Lanka using in situ Chlorophyll-a (Chl-a) measurements and Advanced Spaceborne Thermal Emission and Reflectance Radiometer (ASTER) satellite data. This Lake is located in a mixed land use area with industries, some agricultural lands, middle income and high income housing, tourist hotels and low income housing. From March to October 2013, water samples from five sampling sites were collected once a month parallel to ASTER overpass and Chl-a, nitrate and phosphate contents of each sample were measured using standard laboratory methods. Cloud-free ASTER scenes over the lake during the 2000-2013 periods were acquired for Chl-a estimation and trend analysis. All ASTER images were atmospherically corrected using FLAASH software and in-situ Chl-a data were regressed with atmospherically corrected three ASTER VNIR band ratios of the same date. The regression equation of the band ratio and Chl-a content with the highest correlation, which was the green/red band ratio was used to develop algorithm for generation of 15-m resolution Chl-a distribution maps. According to the ASTER based Chl-a distribution maps it was evident that eutrophication of this lake has gradually increased from 2008-2011. Results also indicated that there had been significantly high eutrophic conditions throughout the year 2013 in several regions, especially in water stagnant areas and adjacent to freshwater outlets. Field observations showed that this lake is receiving various discharges from factories. Unplanned urbanization and inadequacy of proper facilities in the nearby industries for waste management have resulted in the eutrophication of the water body. If the present trends of waste disposal and unplanned urbanization continue, enormous environmental problems would be resulted in future. Results of the present study showed that information from satellite remote

  2. The Agrobacterium tumefaciens Ti Plasmid Virulence Gene virE2 Reduces Sri Lankan Cassava Mosaic Virus Infection in Transgenic Nicotiana benthamiana Plants.

    PubMed

    Resmi, Thulasi Raveendrannair; Hohn, Thomas; Hohn, Barbara; Veluthambi, Karuppannan

    2015-05-01

    Cassava mosaic disease is a major constraint to cassava cultivation worldwide. In India, the disease is caused by Indian cassava mosaic virus (ICMV) and Sri Lankan cassava mosaic virus (SLCMV). The Agrobacterium Ti plasmid virulence gene virE2, encoding a nuclear-localized, single-stranded DNA binding protein, was introduced into Nicotiana benthamiana to develop tolerance against SLCMV. Leaf discs of transgenic N. benthamiana plants, harboring the virE2 gene, complemented a virE2 mutation in A. tumefaciens and produced tumours. Three tested virE2 transgenic plants displayed reduction in disease symptoms upon agroinoculation with SLCMV DNA A and DNA B partial dimers. A pronounced reduction in viral DNA accumulation was observed in all three virE2 transgenic plants. Thus, virE2 is an effective candidate gene to develop tolerance against the cassava mosaic disease and possibly other DNA virus diseases. PMID:26008704

  3. The Agrobacterium tumefaciens Ti Plasmid Virulence Gene virE2 Reduces Sri Lankan Cassava Mosaic Virus Infection in Transgenic Nicotiana benthamiana Plants

    PubMed Central

    Resmi, Thulasi Raveendrannair; Hohn, Thomas; Hohn, Barbara; Veluthambi, Karuppannan

    2015-01-01

    Cassava mosaic disease is a major constraint to cassava cultivation worldwide. In India, the disease is caused by Indian cassava mosaic virus (ICMV) and Sri Lankan cassava mosaic virus (SLCMV). The Agrobacterium Ti plasmid virulence gene virE2, encoding a nuclear-localized, single-stranded DNA binding protein, was introduced into Nicotiana benthamiana to develop tolerance against SLCMV. Leaf discs of transgenic N. benthamiana plants, harboring the virE2 gene, complemented a virE2 mutation in A. tumefaciens and produced tumours. Three tested virE2 transgenic plants displayed reduction in disease symptoms upon agroinoculation with SLCMV DNA A and DNA B partial dimers. A pronounced reduction in viral DNA accumulation was observed in all three virE2 transgenic plants. Thus, virE2 is an effective candidate gene to develop tolerance against the cassava mosaic disease and possibly other DNA virus diseases. PMID:26008704

  4. Identification of amino acid residues of the coat protein of Sri Lankan cassava mosaic virus affecting symptom production and viral titer in Nicotiana benthamiana.

    PubMed

    Kelkar, Vaishali; Kushawaha, Akhilesh Kumar; Dasgupta, Indranil

    2016-06-01

    Sri Lankan cassava mosaic virus (SLCMV) is bipartite begomovirus infecting cassava in India and Sri Lanka. Interestingly, the DNA-A component of the SLCMV alone is able to infect Nicotiana benthamiana causing symptoms of upward leaf rolling and stunting. One of the differences between monopartite and bipartite begomoviruses is the requirement of Coat Protein (CP) for infectivity; CP being essential for the former, but dispensable in the latter. This investigation was aimed to determine the importance of CP in the infectivity of the bipartite SLCMV, behaving as a monopartite virus in N. benthamiana. We tested CP-null mutants, single amino acid replacement mutants and double, triple and quadruple combinations of the above in SLCMV DNA-A, for infectivity, symptom development and viral DNA accumulation in N. benthamiana. While CP-null mutants were non-infectious, a majority of the single amino acid replacement mutants and their combinations retained infectivity, some with attenuated symptoms and reduced viral titers. Some of the combined mutations restored the attenuated symptoms to wild type levels. Some of the mutations were predicted to cause changes in the secondary structure of the CP, which roughly correlated with the attenuation of symptoms and the reduction in viral titers. PMID:26948262

  5. Use of household ingredients as complementary medicines for perceived hypoglycemic benefit among Sri Lankan diabetic patients; a cross-sectional survey

    PubMed Central

    Medagama, Arjuna Bandara; Senadhira, Danusha

    2015-01-01

    Background: Biologic based therapies are frequently used as complementary medicines in diabetes. The aim of this study was to identify the commonly used herbal remedies and their preparations in Sri Lankan patients with Type 2 diabetes. Methods: This is a descriptive, cross-sectional study on 220 diabetic patients using herbal remedies for perceived glycemic benefit. Results: All the patients used their regular conventional medications together with herbal remedies. The most commonly used medication was metformin (91.4%). Ivy gourd (Coccinia grandis) was the most commonly used herbal remedy (32%), followed by crepe ginger (Costus speciosus) (25%) and bitter gourd (Momordica charantia) (20%). Herbal remedies used less frequently were finger millet (Eleusine corocana) (5%), anguna leaves (Wattakaka volubilis) (5%), goat weed (Scoparia dulcis) (4%), Salacia reticulata (4%), fenugreek (Trigonella foenum-graecum) (3%) and tree turmeric (Coscinium fenestratum) (0.5%). None of the patients used commercially available over-the-counter herbal products. The common preparations were salads (72.8%), curries (12.8%), herbal tea (6%), and herbal porridges (6%). Conclusion: The practice of using household ingredients as complementary medicines is common in Sri Lanka. Few herbal remedies and their methods of preparation have limited evidence for efficacy. In view of the frequent use by diabetic patients each needs to be documented for reference and scientifically explored about their hypoglycemic potential. PMID:26401401

  6. Prevalence, patterns and correlates of alcohol consumption and its’ association with tobacco smoking among Sri Lankan adults: a cross-sectional study

    PubMed Central

    2014-01-01

    Background Most studies on alcohol consumption carried out in Sri Lanka are limited to single/few provinces in the island. The objective of this study was to determine the prevalence, patterns and correlates of alcohol consumption among a larger sample of adults in Sri Lanka. Methods This cross-sectional study was conducted in seven of all nine provinces in Sri Lanka, between 2005 and 2006. A nationally representative sample of 5000 adults aged ≥18 years was selected using multi-stage random cluster sampling. Data of 4532 participants were collected using an interviewer administered questionnaire. Data analysis included chi-squared test, multiple logistic regression analysis and Spearman correlation using Stata/SE 10.0 (StataCorp LP., Texas, USA) software package. Results Males were 40%; mean age was 46.1 years (±15.1). The overall, urban and rural prevalence (95% CI) of current drinking was 23.7% (21.7 – 25.7), 29.5% (25.7 – 33.3) and 22.2% (19.8 – 24.7) respectively (p = 0.001). Current (M: 48.1%, F: 1.2%, p < 0.0001) and former (M: 21.4%, F: 0.7%, p < 0.0001) drinking was much higher in males. The highest prevalence of drinking in males (58.9%) and females (2.2%) was in the 30 – 39 and <20 year age groups respectively. Lowest prevalence in men (24.6%) and women (0%) was in the >70 years age-group. Hazardous drinking was seen in 5.2% of men and 0.02% of women. Male sex, urban living and current smoking correlated with both current and hazardous drinking. Lower level of education, and age >70 years positively correlated with hazardous drinking. Conclusions Alcohol is predominantly a problem in Sri Lankan males. In males, both current and hazardous drinking positively correlated with urban living, white collar occupation, Burgher ethnicity and current smoking. Hazardous drinking positively correlated with lower level of education and older age. The data shown here are useful in planning interventions simultaneously targeting alcohol and

  7. Evaluation of adaptogenic and anti-stress effects of Ranahamsa Rasayanaya-A Sri Lankan classical Rasayana drug on experimental animals

    PubMed Central

    Somarathna, K. Indrajith W.K.; Chandola, H. M.; Ravishankar, B.; Pandya, K. N.; Attanayake, A. M. P.; Ashok, B.K.

    2010-01-01

    Various types of stress not only harm the mental function, but also cause diseases by weakening body defenses. Rasayana therapy has an advantage over the conventional Kayachikitsa treatment in such conditions, as it is capable of counteracting the stress, promote the adaptogenic abilities of the body, enhance mental endurance, etc. These are the some of parameters for evaluation the rasayana effect of a drug, therefore the same have been studied to assess the rasayana effect of Ranahamsa Rasayanaya (RR). Experimental models such as forced swimming induced hypothermia and stress induced gastric ulcer formation have been carried out befitting on Charles Foster strain albino rats to determine the rasayana effect of RR. Statistically highly significant decrease in forced swimming induced hypothermia and non-significant decrease in gastric ulcer formation were observed in the treatment groups, when compared to the stress control group. These results show the probable adaptogenic and anti-stress activities of the test drug. The study results support the claims made by the Sri Lankan traditional practitioners that, the test drug is a potent rasayana formulation. PMID:22131691

  8. NA2EDTA ENHANCES THE ABSORPTION OF IRON AND ZINC FROM FORTIFIED RICE FLOUR IN SRI LANKAN CHILDREN

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Rice flour was proposed as a vehicle for iron and zinc fortification in Sri Lanka. Although widely consumed, rice flour has not been evaluated as a fortified food, and the absorption of minerals including iron and zinc from this flour is unknown. Determination of the bioavailability of these nutrien...

  9. Teaching Teachers through Distance Methods: An Evaluation of a Sri Lankan Programme. Education Division Document, No. 40.

    ERIC Educational Resources Information Center

    Dock, Alan W.; And Others

    This report describes the development process of a distance education program in Sri Lanka run by the Institute of Distance Education for nongraduate teachers inservice, and presents results of the program's evaluation. Two teacher education courses--an elementary education course and a combined science/mathematics course--were offered. The…

  10. Na2EDTA enhances the absorption of iron and zinc from fortified rice flour in Sri Lankan children

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Rice flour was proposed as a vehicle for iron and zinc fortification in Sri Lanka. Although widely consumed, rice flour has not been evaluated as a fortified food, and the absorption of minerals including iron and zinc from this flour is unknown. Determination of the bioavailability of these nutrien...

  11. Conversion of bedrock to soil and feedback processes between the surface and the weathering front in a deeply weathered regolith, Central Sri Lankan Highlands

    NASA Astrophysics Data System (ADS)

    Behrens, Ricarda; Bouchez, Julien; Schuessler, Jan A.; Dultz, Stefan; Hewawasam, Tilak; von Blanckenburg, Friedhelm

    2014-05-01

    In the Sri Lankan highlands denudation rates and chemical weathering rates represent the low-end-member in global weathering rates [1, 2]. Here we explore the causes for these low rates by a detailed soil-mineralogical study of a highly weathered deep saprolite profile developed from charnockite bedrock. Spheroidal weathering of the bedrock characterized the weathering front where rounded corestones are produced at the rock-saprolite interface. The first mineral attacked by weathering was found to be pyroxene but plagioclase is the first mineral depleted to near-completion at the corestone-saprolite-boundary. Weathering of pyroxene is initiated by in situ iron oxidation, leading to an increase of porosity due to micro-cracking [3]. The accrued micro cracks allow for fluid transport and the dissolution of biotite and plagioclase. The strong plagioclase weathering leads to formation of high secondary porosity over a small distance and the final disaggregation of bedrock to saprolite. Sequential extraction showed that the first secondary phases are amorphous oxides from which secondary minerals (gibbsite, kaolinite, goethite and minor amounts of smectites) precipitate. Modeling of the strain formation due to increasing volume during iron oxidation in pyroxene and biotite showed that spheroidal weathering can be explained with this process only if the formation of secondary porosity, due to a negative volume budget during primary mineral weathering to secondary phases, occurs. As oxidation is the first occurring reaction, O2 is a rate limiting factor for chemical weathering in this setting. Hence the supply of oxygen and the consumption at depth connects processes at the weathering front with those at the surface as a feedback mechanism. Advective and diffusive transport modeling shows that the feedback will be much more pronounced with dominating diffusive transport. Due to the low porosity of the bedrock the O2 transport in the pristine bedrock occurs via diffusion

  12. DNA barcoding of Sri Lankan phlebotomine sand flies using cytochrome c oxidase subunit I reveals the presence of cryptic species.

    PubMed

    Gajapathy, Kanapathy; Tharmasegaram, Tharmatha; Eswaramohan, Thampoe; Peries, Lalanthika B S L; Jayanetti, Raveendra; Surendran, Sinnathamby N

    2016-09-01

    Sri Lanka is known for high diversity of phlebotomine sand flies and prevalence of cutaneous and visceral leishmaniasis; a disease vectored by sand flies. The taxonomy of phlebotomine sand flies is complicated and often the diversity is over/underrated. The current study aims to use the cytochrome c oxidase gene subunit 1 (COI) sequence and formulate a barcode for the sand fly species in Sri Lanka. A total of 70 samples comprising seven species morphologically identified and collected from dry zone districts of Hambantota, Anuradhapura, Vavuniya, Trincomalee and Jaffna were processed. Neighbour-joining (NJ) tree created using the sequences revealed the species identity is compatible with the current morphology based identification. Further the analysis delineated morphologically identified Se. bailyi, Se babu babu and Se babu insularis into genetically distinct groups. PMID:27180216

  13. Tsunami: Sri Lanka

    Atmospheric Science Data Center

    2013-04-16

    article title:  Deep Ocean Tsunami Waves off the Sri Lankan Coast     ... Imaging SpectroRadiometer (MISR) captured this image of deep ocean tsunami waves about 30-40 kilometers from Sri Lanka's southwestern coast. ... Tsunami: Sri Lanka location:  Asia Indian Ocean thumbnail:  ...

  14. Feeling the blues of infertility in a South Asian context: psychological well-being and associated factors among Sri Lankan women with primary infertility.

    PubMed

    Lansakara, Nirosha; Wickramasinghe, Ananda Rajitha; Seneviratne, Harshalal Rukka

    2011-06-21

    Primary infertility may have a considerable impact on the psychological well-being of women. In the present study, the authors investigated the psychological well-being and its correlates among Sri Lankan women with primary infertility. A total of 177 women with primary infertility were compared with 177 fertile women matched for age and duration of marriage to identify differences in the psychological well-being between the two groups. They were recruited from a prevalence survey conducted in the district of Colombo, Sri Lanka from August 2005 to February 2006. The General Health Questionnaire-30 (GHQ-30) and Mental Health sub-components of the Short Form-36 (SF-36) were used to measure psychological well-being. In addition, infertile women with and without psychological distress were compared to identify the social, marital, treatment, and demographic factors independently associated with psychological distress. A significantly higher proportion of women with primary infertility (66.1%; 95% CI 58.6-73.0%) had psychological distress as compared to fertile women (18.6 %; 95% CI 13.2-25.2%; P < 0.001). After adjustment for confounding factors, infertile women who were psychologically distressed were significantly less educated (OR = 55.3; 95% CI 15.2-201.0), had poor marital communication (OR = 3.5; 95% CI 1.3-9.8), had a higher priority for having children (OR = 4.2; 95% CI 1.3-13.8), and had been previously (OR = 39.1; 95% CI 8.3-185.4) or currently (OR = 11.0; 95% CI 3.0-40.6) investigated/treated for infertility when compared with infertile women without distress. Women with primary infertility reported more distress as compared to fertile women. Psychological distress among infertile women was associated with poorer education, being previously/currently investigated/treated, placing higher importance on having children, and having poor marital communication. The need for psychological intervention targeting infertile women in clinics and community settings is

  15. Preexisting Neutralizing Antibody Responses Distinguish Clinically Inapparent and Apparent Dengue Virus Infections in a Sri Lankan Pediatric Cohort

    PubMed Central

    Corbett, Kizzmekia S.; Katzelnick, Leah; Tissera, Hasitha; Amerasinghe, Ananda; de Silva, Aruna Dharshan; de Silva, Aravinda M.

    2015-01-01

    Dengue viruses (DENVs) are mosquito-borne flaviviruses that infect humans. The clinical presentation of DENV infection ranges from inapparent infection to dengue hemorrhagic fever and dengue shock syndrome. We analyzed samples from a pediatric dengue cohort study in Sri Lanka to explore whether antibody responses differentiated clinically apparent infections from clinically inapparent infections. In DENV-naive individuals exposed to primary DENV infections, we observed no difference in the quantity or quality of acquired antibodies between inapparent and apparent infections. Children who experienced primary infections had broad, serotype–cross-neutralizing antibody responses that narrowed in breadth to a single serotype over a 12-month period after infection. In DENV immune children who were experiencing a repeat infection, we observed a strong association between preexisting neutralizing antibodies and clinical outcome. Notably, children with preexisting monospecific neutralizing antibody responses were more likely to develop fever than children with cross-neutralizing responses. Preexisting DENV neutralizing antibodies are correlated with protection from dengue disease. PMID:25336728

  16. Population genetic structure of the Plasmodium vivax circumsporozoite protein (Pvcsp) in Sri Lanka.

    PubMed

    Dias, Sajani; Wickramarachchi, Thilan; Sahabandu, Imeshi; Escalante, Ananias A; Udagama, Preethi V

    2013-04-15

    Molecular methods elucidate evolutionary and ecological processes in parasites, where interaction between hosts and parasites enlighten the evolution of parasite lifestyles and host defenses. Population genetics of Plasmodium vivax parasites accurately describe transmission dynamics of the parasites and evaluation of malaria control measures. As a first generation vaccine candidate against malaria, the Circumsporozoite Protein (CSP) has demonstrated significant potential in P. falciparum. Extensive polymorphism hinders the development of a potent malaria vaccine. Hence, the genetic diversity of Pvcsp was investigated for the first time in 60 Sri Lankan clinical isolates by obtaining the nucleotide sequence of the central repeat (CR) domain and examining the polymorphism of the peptide repeat motifs (PRMs), the genetic diversity indices and phylogenetic relationships. PCR amplicons determined size polymorphism of 610, 700 and 710 bp in Pvcsp of Sri Lanka where all amino acid sequences obtained were of the VK210 variant, consisting variable repeats of 4 different PRMs. The two most abundant PRMs of the CR domain, GDRADGQPA and GDRAAGQPA consisted ~2-4 repeats, while GNRAAGQPA was unique to the island. Though, different nucleotide sequences termed repeat allotypes (RATs) were observed for each PRM, these were synonymous contributing to a less polymorphic CR domain. The genetic diversity of Pvcsp in Sri Lanka was due to the number of repetitive peptide repeat motifs, point mutations, and intragenic recombination. The 19 amino acid haplotypes defined were exclusive to Sri Lanka, whereas the 194 Pvcsp sequences of global isolates generated 57 more distinct a.a. haplotypes of the VK210 variant. Strikingly, the CR domain of both VK210 and VK247 variants was under purifying selection interpreting the scarcity of CSP non-synonymous polymorphisms. Insights to the distribution of RATs in the CR region with geographic clustering of the P. vivax VK210 variant were revealed. The

  17. Elevated levels of whole blood nickel in a group of Sri Lankan women with endometriosis: a case control study

    PubMed Central

    2013-01-01

    Background Endometriosis is characterized by the persistence of endometrial tissue in ectopic sites outside the uterine cavity. Presence of nickel, cadmium and lead in ectopic endometrial tissue has been reported previously. While any association between blood levels of nickel and endometriosis is yet to be described in literature, conflicting reports are available with regards to cadmium and lead levels in blood and urine. Findings In fifty patients with endometriosis and fifty age-matched controls confirmed by laparoscopy or laparotomy, whole blood samples were collected and digested using supra pure 65% HNO3. Whole blood levels of nickel and lead were measured using Total Reflection X-ray Fluorescence (TXRF) while cadmium levels were evaluated using graphite furnace atomic absorption spectroscopy (GFASS). Women with endometriosis had significantly higher (P=0.016) geometric mean (95% CI) whole blood nickel levels [2.6(1.9-3.3) μg/L] as compared to women without endometriosis [0.8 (0.7-0.9) μg/L]. Whole blood levels of cadmium and lead were similar between the two groups. Conclusions Although women with endometriosis in this study population had higher levels of nickel in whole blood compared to controls, whether nickel could be considered as an aetiological factor in endometriosis remains inconclusive in view of the smaller sample that was evaluated. PMID:23317102

  18. Outcomes of Parental Use of Psychological Aggression on Children: A Structural Model from Sri Lanka

    ERIC Educational Resources Information Center

    de Zoysa, Piyanjali; Newcombe, Peter A.; Rajapakse, Lalini

    2010-01-01

    The objective of this study was to explore the existence and, if so, the nature of the association between parental use of psychological aggression and psychological maladjustment in a 12-year-old Sri Lankan school population. A stratified random sampling technique was used to select 1,226 children from Colombo district schools. Three instruments,…

  19. Prevalence and severity of micronutrient deficiency: a cross-sectional study among adolescents in Sri Lanka

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In order to determine the prevalence of micronutrient deficiencies (iron, zinc and folate) in Sri Lankan adolescent school children and the extent to which multiple micronutrient deficiencies exist in this population, a cross-sectional survey (2003) in the Galle district of the micronutrient and ant...

  20. EQ-5D-3L Derived Population Norms for Health Related Quality of Life in Sri Lanka

    PubMed Central

    Kularatna, Sanjeewa; Whitty, Jennifer A.; Johnson, Newell W.; Jayasinghe, Ruwan; Scuffham, Paul A.

    2014-01-01

    Background Health Related Quality of Life (HRQoL) is an important outcome measure in health economic evaluation that guides health resource allocations. Population norms for HRQoL are an essential ingredient in health economics and in the evaluation of population health. The aim of this study was to produce EQ-5D-3L-derived population norms for Sri Lanka. Method A population sample (n =  780) was selected from four districts of Sri Lanka. A stratified cluster sampling approach with probability proportionate to size was employed. Twenty six clusters of 30 participants each were selected; each participant completed the EQ-5D-3L in a face-to-face interview. Utility weights for their EQ-5D-3L health states were assigned using the Sri Lankan EQ-5D-3L algorithm. The population norms are reported by age and socio-economic variables. Results The EQ-5D-3L was completed by 736 people, representing a 94% response rate. Sixty per cent of the sample reported being in full health. The percentage of people responding to any problems in the five EQ-5D-3L dimensions increased with age. The mean EQ-5D-3L weight was 0.85 (SD 0.008; 95%CI 0.84-0.87). The mean EQ-5D-3L weight was significantly associated with age, housing type, disease experience and religiosity. People above 70 years of age were 7.5 times more likely to report mobility problems and 3.7 times more likely to report pain/discomfort than those aged 18-29 years. Those with a tertiary education were five times less likely to report any HRQoL problems than those without a tertiary education. A person living in a shanty was 4.3 more likely to have problems in usual activities than a person living in a single house. Conclusion The population norms in Sri Lanka vary with socio-demographic characteristics. The socioeconomically disadvantaged have a lower HRQoL. The trends of population norms observed in this lower middle income country were generally similar to those previously reported in high income countries. PMID

  1. Rare hemoglobin variants: Hb G-Szuhu (HBB: c.243C>G), Hb G-Coushatta (HBB: c.68A>C) and Hb Mizuho (HBB: c.206T>C) in Sri Lankan families.

    PubMed

    Perera, P Shiromi; Silva, Ishari; Hapugoda, Menaka; Wickramarathne, Merita N; Wijesiriwardena, Indira; Efremov, Dimitar G; Fisher, Christopher A; Weatherall, David J; Premawardhena, Anuja

    2015-01-01

    In this short communication, we describe the clinical presentation of unusual hemoglobin (Hb), variants in three Sri Lankan cases under study for β-thalassemia intermedia (β-TI). We believe this is the first report on their occurrence in Sri Lanka as well as from the Indian subcontinent. During a molecular study performed on β-TI patients, we identified three unusual Hb variants as Hb G-Szuhu (HBB: c.243C>G), Hb G-Coushatta (HBB: c.68A>C) and Hb Mizuho (HBB: c.206T>C) in three unrelated families. Hb G-Szuhu and Hb G-Coushatta were found in combination with the common β-thalassemia (β-thal) mutation, IVS-I-5 (G>C). Both probands had mild anemia with greatly reduced red cell indices and had non palpable livers and spleens, however, by ultrasound, both were observed to be enlarged. The final Hb variant, Hb Mizuho, was identified as a heterozygous mutation found in both proband and his mother. Both family members had severe anemia and were regularly transfused and had increased red cell parameters. PMID:25572187

  2. Creative Destruction and the Aftermath of the Tsunami: Aiding the Recovery of Southern Sri Lankan Small Businesses in the Face of Inertia

    ERIC Educational Resources Information Center

    Perera, Travis

    2007-01-01

    The tsunami of 26 December 2004 killed over 35,000 people in Sri Lanka, made 400,000 jobless and damaged the economy by 6.5%. The physical damage was around U.S. $1.5 billion, with reconstruction costing $2 billion. Although entrepreneurs are opportunity seekers, take risks and thrive in uncertainty, the alignment of competency and institutional…

  3. Is Risk Factor-based Screening Good Enough to Detect Gestational Diabetes Mellitus in High-Risk Pregnant Women? A Sri Lankan Experience

    PubMed Central

    Meththananda Herath, H. M.; Weerarathna, Thilak Priyantha; Weerasinghe, Nayani Prasangika

    2016-01-01

    Background: There is a long lasting dilemma over the ideal screening and diagnostic method in gestational diabetes mellitus (GDM). Even though universal screening is commonly practiced, selective screening based on risk factors is also practiced in some center. The aim of this study is to evaluate the most appropriate method to screen GDM in high-risk pregnant women in Sri Lanka. Methods: This study was a clinic-based, cross-sectional study conducted in a tertiary referral center, Sri Lanka. All women underwent 75 g oral glucose tolerance test at 24–28 weeks of gestation. Diagnosis of GDM was made according to the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) and World Health Organization (WHO) criteria. Results: With universal screening using IADPSG criteria, 23.2% (105/452) were found to have GDM and with risk factor-based screening 20.1% (91/452) were detected to have GDM. The prevalence of GDM dropped to 18.1% when GDM was diagnosed using the WHO criteria with universal screening approach. It was further dropped to 15.7% when the WHO criteria were used along with risk factors-based screening approach. Conclusions: The IADPSG criteria labeled considerably higher number of women as having GDM compared to the WHO criteria. With regards to the screening methods, the risk-based screening had a lower detection rate of GDM; however, it reduced the necessity of screening of women by around 20%.

  4. Agricultural Adaptation and Water Management in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Stone, E.; Hornberger, G. M.

    2014-12-01

    Efficient management of freshwater resources is critical as concerns with water security increase due to changes in climate, population, and land use. Effective water management in agricultural systems is especially important for irrigation and water quality. This research explores the implications of tradeoffs between maximization of crop yield and minimization of nitrogen loss to the environment, primarily to surface water and groundwater, in rice production in Sri Lanka. We run the DeNitrification-DeComposition (DNDC) model under Sri Lankan climate and soil conditions. The model serves as a tool to simulate crop management scenarios with different irrigation and fertilizer practices in two climate regions of the country. Our investigation uses DNDC to compare rice yields, greenhouse gas (GHG) emissions, and nitrogen leaching under different cultivation scenarios. The results will inform best practices for farmers and decision makers in Sri Lanka on the management of water resources and crops.

  5. Village School in Sri Lanka.

    ERIC Educational Resources Information Center

    Baker, Victoria J.

    2000-01-01

    Describes education in poor Sri Lankan villages, examining the effects of poverty (poor teacher training, lack of equipment, and inability of students to attend); the influence of ministerial-level traditional or negative attitudes (questioning the worth of investing in equal education in remote rural areas); and weaknesses in the system that…

  6. Relationship between Body mass index (BMI) and body fat percentage, estimated by bioelectrical impedance, in a group of Sri Lankan adults: a cross sectional study

    PubMed Central

    2013-01-01

    Background Body Mass Index (BMI) is used as a useful population-level measure of overweight and obesity. It is used as the same for both sexes and for all ages of adults. The relationship between BMI and body fat percentage (BF %) has been studied in various ethnic groups to estimate the capacity of BMI to predict adiposity. We aimed to study the BMI–BF% relationship, in a group of South Asian adults who have a different body composition compared to presently studied ethnic groups. We examined the influence of age, gender in this relationship and assessed its’ linearity or curvilinearity. Methods A cross sectional study was conducted, where adults of 18–83 years were grouped into young (18–39 years) middle aged (40–59 years) and elderly (>60 years). BF% was estimated from bioelectrical impedance analysis. Pearsons’ correlation coefficient(r) was calculated to see the relationship between BMI-BF% in the different age groups. Multiple regression analysis was performed to determine the effect of age and gender in the relationship and polynomial regression was carried out to see its’ linearity. The relationships between age-BMI, age-BF % were separately assessed. Results Out of 1114 participants, 49.1% were males. The study sample represented a wide range of BMI values (14.8-41.1 kg/m2,Mean 23.8 ± 4.2 kg/m2). A significant positive correlation was observed between BMI-BF%, in males (r =0.75, p < 0.01; SEE = 4.17) and in females (r = 0.82, p < 0.01; SEE = 3.54) of all ages. Effect of age and gender in the BMI-BF% relationship was significant (p < 0.001); with more effect from gender. Regression line found to be curvilinear in nature at higher BMI values where females (p < 0.000) having a better fit of the curve compared to males (p < 0.05). In both genders, with increase of age, BMI seemed to increase in curvilinear fashion, whereas BF% increased in a linear fashion. Conclusions BMI strongly correlate with BF

  7. Historical Evolution and Present Status of Family Medicine in Sri Lanka

    PubMed Central

    Ramanayake, R. P. J. C.

    2013-01-01

    Sri Lankan health system consists of Allopathic, Ayurvedic, Unani, and several other systems of medicine and allopathic medicine is catering to the majority of the health needs of the people. As in many other countries, Sri Lankan health system consists of both the state and the private sector General practitioners, MOs in OPDs of hospitals and MOs of central dispensaries, provide primary medical care in Sri Lanka. Most of the general practices are solo practices. One does not need postgraduate qualification or training in general practice to start a general practice. There is no registered population for any particular health care institution in the state sector or in the private sector and there is no strict referral procedure from primary care to secondary or tertiary care. Family doctors have been practicing in Sri Lanka for well over 150 years. The first national organization of general practitioners was Independent Medical Practitioner (IMPA)'s organization which was founded in 1929 and the College of General Practitioners of Sri Lanka was founded in 1974. College conducts its own Membership Course and Examination (MCGP) since 1999. Family Medicine was introduced to undergraduate curriculum in Sri Lanka in early 1980s and now almost all the medical faculties in the country have included Family Medicine in their curricula. In 1979, General Practice/Family Medicine was recognized as a specialty in Sri Lanka by the postgraduate institute of Medicine. Diploma in Family Medicine (DFM) and MD Family Medicine are the pathways for postgraduate training in Sri Lanka. At present 50 to 60 doctors enroll for DFM every year and the country has about 20 specialists (with MD) in Family Medicine. The author's vision for the future is that all the primary care doctors to have a postgraduate qualification in Family Medicine either DFM, MD, or MCGP which is a far cry from the present status. PMID:24479065

  8. Malathion resistance and prevalence of the malathion carboxylesterase mechanism in populations of mosquito vectors of disease in Sri Lanka.

    PubMed Central

    Karunaratne, S. H.; Hemingway, J.

    2001-01-01

    OBJECTIVE: To determine the levels of malathion resistance and prevalence of the malathion carboxylesterase mechanism among mosquitoes in Sri Lanka. METHODS: Bioassays were carried out using WHO-recommended methods on samples of the following Sri Lankan mosquito vectors: Culex quinquefasciatus, C. tritaeniorhynchus, C gelidus, Anopheles culicifacies B, A. subpictus, Aedes aegypti and A. albopictus. FINDINGS Malathion-specific carboxylesterase mechanisms were found in A. culicifaies and A. subpictus, both giving high rates of insecticide metabolism. In contrast, malathion resistance in C. quinquefasciatus and C. tritaeniorhynchus is linked to broad-spectrum resistance to organophosphorus compounds due to elevated levels of esterases that sequester malaoxon, but are unable to metabolize malathion. CONCLUSIONS: Resistance among the Anophelesspp. must have occurred as a direct result of antimalarial activities, since malathion use in Sri Lanka is limited to public health treatments. In contrast, resistance among Culex spp. has resulted from large-scale use of the organophosphorus insecticide group as larvicides for filariasis control and on rice paddy, where C tritaeniorhynchus predominantly breeds, for agricultural purposes. PMID:11731814

  9. Hemidactylus parvimaculatus (Sri Lankan spotted house gecko)

    USGS Publications Warehouse

    Glorioso, Brad M.

    2016-01-01

    USA: LOUISIANA: St. Tammany Parish: private property ca. 4 km S of Abita Springs, E of State Hwy 59, and N of Interstate 12 (30.44000°N, 90.02000°W; WGS 84). 18 August 2013. Brad M. Glorioso. Verified by David Heckard. Florida Museum of Natural History (UF 176422, photo voucher). New parish record. This species was first reported in the Americas in the vicinity of Audubon Zoo in New Orleans, Louisiana (Heckard et al. 2013. IRCF Reptiles & Amphibians 20:192–196). This is the third report of this species in Louisiana (Heckard et al. 2013, op. cit.; Borgardt 2015. Herpetol. Rev. 46:217), and is now documented from Orleans, Jefferson, and St. Tammany parishes in southeast Louisiana. The individual was located at night, ca. 10 m from a dwelling on the forest floor amid a downed picket fence, which was resting atop a thick layer of pine needles. There are H. turcicus at the property, but this individual was recognized as unusual, and many photos were taken before releasing the animal. It was not until much later that it was determined to be H. parvimaculatus. The origin of this individual is unknown, as the owners of this 1.62-ha property are elderly and do not keep any pets. Subsequent casual searches have not turned up any new individuals. I thank David Heckard for his help with identification and discussion of this species in Louisiana.

  10. The Asian Tsunami and Problem-Based Learning for Postgraduate Students in Sri Lanka

    ERIC Educational Resources Information Center

    Jayawardana, A. K. L.; O'Donnell, Michael

    2007-01-01

    The Asian Tsunami struck Sri Lanka on December 26, 2004. Sri Lanka was the second worst affected country after Indonesia, and this natural disaster killed in excess of 35,000 people and displaced over 1 million. The article explores the Tsunami Disaster Management Program developed by one Sri Lankan university: the Postgraduate Institute of…

  11. Art Therapy with Child Tsunami Survivors in Sri Lanka

    ERIC Educational Resources Information Center

    Chilcote, Rebekah L.

    2007-01-01

    This paper details art therapy with children affected by the December 2004 tsunami in Sri Lanka. Over 30,000 Sri Lankans lost their lives when the tsunami decimated coastal areas. The child survivors witnessed horrific traumatic events and the loss of loved ones, but had not been given opportunity to express their grief and pain. A 4-week art…

  12. Landmarks of History of Soil Science in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Mapa, R.

    2012-04-01

    Sri Lanka is a tropical Island in the Southern tip of Indian subcontinent positioned at 50 55' to 90 50' N latitude and 790 42' to 810 53' E longitude surrounded by the Indian Ocean. It is an island 435 km in length and 224 km width consisting of a land are of 6.56 million ha with a population of 20 million. In area wise it is ranked as 118th in the world, where at present ranked as 47 in population wise and ranked 19th in population density. The country was under colonial rule under Portuguese, Dutch and British from 1505 to 1948. The majority of the people in the past and present earn their living from activities based on land, which indicates the important of the soil resource. The objective of this paper is to describe the landmarks of the history of Soil Science to highlight the achievements and failures, which is useful to enrich our present understanding of Sri Lankan soils. The landmarks of the history of Soil Science in Sri Lanka can be divided to three phases namely, the early period (prior to 1956), the middle period (1956 to 1972) and the present period (from 1972 onwards). During the early period, detailed analytical studies of coffee and tea soils were compiled, and these gave mainly information on up-country soils which led to fertilizer recommendations based on field trials. In addition, rice and forest soils were also studied in less detail. The first classification of Sri Lankan soils and a provisional soil map based on parent material was published by Joachim in 1945 which is a major landmark of history of Soil Science in Sri Lanka. In 1959 Ponnamperuma proposed a soil classification system for wetland rice soils. From 1963 to 1968 valuable information on the land resource was collected and documented by aerial resource surveys funded by Canada-Ceylon Colombo plan aid project. This covered 18 major river basins and about 1/4th of Sri Lanka, which resulted in producing excellent soil maps and information of the areas called the Kelani Aruvi Ara

  13. International Enterprise Education in Sri Lanka: A Blended Approach

    ERIC Educational Resources Information Center

    Kasturiratne, Dulekha; Lean, Jonathan; Phippen, Andy

    2012-01-01

    Purpose: The purpose of this paper is to explore how enterprise education was adapted from a UK higher education institution (HEI) setting into an international context through collaboration with two Sri Lankan universities. It demonstrates the value of enterprise education in different cultures, and presents learning from the challenges faced by…

  14. Culture, Gender, and Suicidal Behavior in Sri Lanka.

    ERIC Educational Resources Information Center

    Marecek, Jeanne

    1998-01-01

    The current pattern of suicides, including sex differences, is described. Institutional practices, material conditions, and social norms are explored. A study inquiring into Sri Lankan's perceptions of the problem is presented. Gender differences and cultural meanings of suicide are discussed, and questions addressing the source of suicidal…

  15. Staffing Practices in the Private Sector in Sri Lanka

    ERIC Educational Resources Information Center

    Wickramasinghe, Vathsala

    2007-01-01

    Purpose: This paper seeks to present and discuss the findings of a study of staffing practices in the Sri Lankan private sector with particular reference to junior level managerial jobs. The scope of staffing practices consisted of six major areas, namely the usage of information from job analysis in staffing, the sources of labour, selection…

  16. Population structure and virulence content of avian pathogenic Escherichia coli isolated from outbreaks in Sri Lanka.

    PubMed

    Dissanayake, D R A; Octavia, Sophie; Lan, Ruiting

    2014-01-31

    Avian pathogenic Escherichia coli (APEC) causes economically significant infections in poultry. The genetic diversity of APEC and phylogenetic relationships within and between APEC and other pathogenic E. coli are not yet well understood. We used multilocus sequence typing (MLST), PCR-based phylogrouping and virulence genotyping to analyse 75 avian E. coli strains, including 55 isolated from outbreaks of colisepticaemia and 20 from healthy chickens. Isolates were collected from 42 commercial layer and broiler chicken farms in Sri Lanka. MLST identified 61 sequence types (ST) with 44 being novel. The most frequent ST, ST48, was represented by only six isolates followed by ST117 with four isolates. Phylogenetic clusters based on MLST sequences were mostly comparable to phylogrouping by PCR and MLST further differentiated phylogroups B1 and D into two subgroups. Genotyping of 16 APEC associated virulence genes found that 27 of the clinical isolates and one isolate from a healthy chicken belonged to highly virulent genotype according to previously established classification schemes. We found that a combination of four genes, ompT, hlyF, iroN and papC, gave a comparable prediction to that of using five and nine genes by other studies. Four STs (ST10, ST48, ST117 and ST2016) contained APEC isolates from this study and human UPEC isolates reported by others, suggesting that these STs are potentially zoonotic. Our results enhanced the understanding of APEC population structure and virulence association. PMID:24388626

  17. "Education Is All about Opportunities, Isn't It?": A Biographical Perspective on Learning and Teaching English in Sri Lanka

    ERIC Educational Resources Information Center

    Hayes, David

    2010-01-01

    In this article, David Hayes explores the language learning and teaching experiences of a teacher of English in Sri Lanka. He shows how the acquisition of English enabled the teacher to access the social capital available to speakers of English, which holds a divisive place in postcolonial Sri Lankan society. In his reflections on his career, this…

  18. A new species of the genus Calotes (Squamata: Agamidae) from high elevations of the Knuckles massif of Sri Lanka.

    PubMed

    Amarasinghe, A A Thasun; Karunarathna, D M S Suranjan; Hallermann, Jakob; Fujinuma, Junichi; Grillitsch, Heinz; Campbell, Patrick D

    2014-01-01

    A new species of agamid lizard, of the genus Calotes, is described based on morphological evidence. This species is restricted to the Knuckles massif (>900 m elevation) of Sri Lanka. The genus Calotes consists of seven species in Sri Lanka, five of which appear to form an endemic radiation. The new species most closely resembles C. liocephalus Günther, 1872 which has an isolated population in the central highlands and is only known from Pundaluoya (~1000m), Dickoya (~1200m), Upcot (~1400m), Agrapatanas (1665m) and Peak Wilderness (Sri Pada) (>1400m). The populations from Pundaluoya and Dickoya appear to be locally extinct from the wild and are known only from museum specimens collected over 120 years ago. Males of the new species are different from males of C. liocephalus because of the absence of a gular pouch; by having mid gular scales smaller in size than those of its counterpart; scales on the snout which are larger in size than those on the occipital and forehead; pectoral scales which are not enlarged; elongated subcaudal scales; slightly carinate and acuminate abdominal scales; and scales on venter which are somewhat larger in size than those on dorsum at the same level. Finally, we also redescribe Calotes liocephalus, and provide a key to the Sri Lankan species of genus Calotes. PMID:24872171

  19. Diffusion of a Sustainable Farming Technique in Sri Lanka: An Agent-Based Modeling Approach

    NASA Astrophysics Data System (ADS)

    Jacobi, J. H.; Gilligan, J. M.; Carrico, A. R.; Truelove, H. B.; Hornberger, G.

    2012-12-01

    We live in a changing world - anthropogenic climate change is disrupting historic climate patterns and social structures are shifting as large scale population growth and massive migrations place unprecedented strain on natural and social resources. Agriculture in many countries is affected by these changes in the social and natural environments. In Sri Lanka, rice farmers in the Mahaweli River watershed have seen increases in temperature and decreases in precipitation. In addition, a government led resettlement project has altered the demographics and social practices in villages throughout the watershed. These changes have the potential to impact rice yields in a country where self-sufficiency in rice production is a point of national pride. Studies of the climate can elucidate physical effects on rice production, while research on social behaviors can illuminate the influence of community dynamics on agricultural practices. Only an integrated approach, however, can capture the combined and interactive impacts of these global changes on Sri Lankan agricultural. As part of an interdisciplinary team, we present an agent-based modeling (ABM) approach to studying the effects of physical and social changes on farmers in Sri Lanka. In our research, the diffusion of a sustainable farming technique, the system of rice intensification (SRI), throughout a farming community is modeled to identify factors that either inhibit or promote the spread of a more sustainable approach to rice farming. Inputs into the ABM are both physical and social and include temperature, precipitation, the Palmer Drought Severity Index (PDSI), community trust, and social networks. Outputs from the ABM demonstrate the importance of meteorology and social structure on the diffusion of SRI throughout a farming community.

  20. Feasibility of hair sampling to assess levels of organophosphate metabolites in rural areas of Sri Lanka.

    PubMed

    Knipe, D W; Jayasumana, C; Siribaddana, S; Priyadarshana, C; Pearson, M; Gunnell, D; Metcalfe, C; Tzatzarakis, M N; Tsatsakis, A M

    2016-05-01

    Measuring chronic pesticide exposure is important in order to investigate the associated health effects. Traditional biological samples (blood/urine) are difficult to collect, store and transport in large epidemiological studies in settings such as rural Asia. We assessed the acceptability of collecting hair samples from a rural Sri Lankan population and found that this method of data collection was feasible. We also assessed the level of non-specific metabolites (DAPS) of organophosphate pesticides in the hair samples. The median concentration (pg/mg) of each DAP was: diethyl phosphate: 83.3 (IQI 56.0, 209.4); diethyl thiophosphate: 34.7 (IQI 13.8, 147.9); diethyl dithiophosphate: 34.5 (IQI 23.4, 55.2); and dimethyl phosphate: 3 (IQI 3, 109.7). Total diethylphosphates were recovered in >80% of samples and were positively correlated with self-reported pesticide exposure. PMID:26894816

  1. Feasibility of hair sampling to assess levels of organophosphate metabolites in rural areas of Sri Lanka

    PubMed Central

    Knipe, D.W.; Jayasumana, C.; Siribaddana, S.; Priyadarshana, C.; Pearson, M.; Gunnell, D.; Metcalfe, C.; Tzatzarakis, M.N.; Tsatsakis, A.M.

    2016-01-01

    Measuring chronic pesticide exposure is important in order to investigate the associated health effects. Traditional biological samples (blood/urine) are difficult to collect, store and transport in large epidemiological studies in settings such as rural Asia. We assessed the acceptability of collecting hair samples from a rural Sri Lankan population and found that this method of data collection was feasible. We also assessed the level of non-specific metabolites (DAPS) of organophosphate pesticides in the hair samples. The median concentration (pg/mg) of each DAP was: diethyl phosphate: 83.3 (IQI 56.0, 209.4); diethyl thiophosphate: 34.7 (IQI 13.8, 147.9); diethyl dithiophosphate: 34.5 (IQI 23.4, 55.2); and dimethyl phosphate: 3 (IQI 3, 109.7). Total diethylphosphates were recovered in >80% of samples and were positively correlated with self-reported pesticide exposure. PMID:26894816

  2. Student Misconceptions about Plant Transport--A Sri Lankan Example

    ERIC Educational Resources Information Center

    Vitharana, P. R. K. A.

    2015-01-01

    Students bring with them their own misconceptions to the science classes and it becomes a barrier in developing new concepts. Therefore, identifying misconceptions is an essential component in teaching science. The objective of this study was to identify 10th grade students' misconceptions on plant transport with the use of two-tier diagnostic…

  3. Viper bites complicate chronic agrochemical nephropathy in rural Sri Lanka

    PubMed Central

    2014-01-01

    Snakebite is a common occupational health hazard among Sri Lankan agricultural workers, particularly in the North Central Province. Viperine snakes, mainly Russell’s viper envenomation, frequently lead to acute renal failure. During the last two decades, an agrochemical nephropathy, a chronic tubulointerstitial disease has rapidly spread over this area leading to high morbidity and mortality. Most of the epidemiological characteristics of these two conditions overlap, increasing the chances of co-occurrence. Herein, we describe four representative cases of viperine snakebites leading to variable clinical presentations, in patients with chronic agrochemical nephropathy, including two patients presented with acute and delayed anuria. These cases suggest the possibility of unusual manifestations of snakebite in patients with Sri Lankan agrochemical nephropathy, of which the clinicians should be aware. It could be postulated that the existing scenario in the Central America could also lead to similar clinical presentations. PMID:25136354

  4. Free-Education in Sri Lanka. Does It Eliminate the Family Effect?

    ERIC Educational Resources Information Center

    Ranasinghe, Athula; Hartog, Joop

    2002-01-01

    Uses human-capital theory to model and estimate the school enrollment and length of schooling decisions of Sri Lankans. Finds a positive association between family background and education decisions. In particular, mother's education and parents' income have a strong effect on the education decisions. (Contains 26 references.) (Authors/PKP)

  5. Counselling in Areas of Armed Conflict: The Case Jaffna, Sri Lanka.

    ERIC Educational Resources Information Center

    van der Veer, Guus; Somasundaram, Daya; Damian S.

    2003-01-01

    Counseling is discussed in relation to traditional resources of the Tamil community for dealing with psychosocial and mental health problems. Describes some problems of clients affected by the armed conflict, approaches of local counselors and mental health professionals, and training offered to future Sri Lankan counselors who want to work with…

  6. Factors Affecting Mental Health of Local Staff Working in the Vanni Region, Sri Lanka

    PubMed Central

    Cardozo, Barbara Lopes; Crawford, Carol; Petit, Pilar; Ghitis, Frida; Sivilli, Teresa I.; Scholte, Willem F.; Ager, Alastair; Eriksson, Cynthia

    2016-01-01

    In the aftermath of the civil war that extended from 1983–2009, humanitarian organizations provided aid to the conflict-affected population of the Vanni region in northern Sri Lanka. In August, 2010, a needs assessment was conducted to determine the mental-health status of Sri Lankan national humanitarian aid staff working in conditions of stress and hardship, and consider contextual and organizational characteristics influencing such status. A total of 398 staff members from nine organizations working in the Vanni area participated in the survey, which assessed stress, work characteristics, social support, coping styles, and symptoms of psychological distress. Exposure to traumatic, chronic, and secondary stressors was common. Nineteen percent of the population met criteria for posttraumatic stress disorder (PTSD), 53% of participants reported elevated anxiety symptoms, and 58% reported elevated depression symptoms. Those reporting high levels of support from their organizations were less likely to suffer depression and PTSD symptoms than those reporting lower levels of staff support (OR =.23, p < .001) and (OR =.26, p < .001), respectively. Participants who were age 55 or older were significantly less likely to suffer anxiety symptoms than those who were between 15 and 34 years of age (OR =.13, p = .011). Having experienced travel difficulties was significantly associated with more anxiety symptoms (OR = 3.35, p < .001). It was recommended that organizations provide stress-management training and increase support to their staff. PMID:27099648

  7. Spontaneously resolving cerebellar syndrome as a sequelae of dengue viral infection: a case series from Sri Lanka.

    PubMed

    Weeratunga, Praveen N; Caldera, H P Manjula C; Gooneratne, I Kishara; Gamage, Ranjanie; Perera, W Sujith P; Ranasinghe, Gayan V; Niraj, Mahboob

    2014-06-01

    Sri Lanka is hyperendemic for dengue viral infection. Dengue has a wide spectrum of neurological manifestations including previously reported Sri Lankan cases with a 6th nerve palsy and a cerebellar syndrome from a co-infection with dengue and Epstein-Barr virus. This series describes a spontaneously resolving cerebellar syndrome following a dengue viral infection. Dengue is potentially an important cause of cerebellar syndromes in countries hyperendemic for the disease; patients need further studies to identify the responsible serotypes. PMID:23840070

  8. Exposure to conflict and disaster: A national survey on the prevalence of psychotic experiences in Sri Lanka.

    PubMed

    Keraite, Arune; Sumathipala, Athula; Siriwardhana, Chesmal; Morgan, Craig; Reininghaus, Ulrich

    2016-03-01

    Recent research conducted in high-income countries suggests psychotic experiences are common in the general population, but evidence from low- and middle-income countries (LMIC) remains limited. Sri Lanka is a LMIC affected by three decades of civil conflict and, in 2004, a devastating tsunami. This study aimed to investigate the prevalence of psychotic experiences in a general population sample in Sri Lanka and associations with conflict- and tsunami-related trauma. This is a first National Mental Health Survey conducted in Sri Lanka. A cross-sectional, multi-stage, cluster sampling design was used to estimate the prevalence of psychotic symptoms. Data on socio-demographic characteristics, conflict- and tsunami-related trauma, and psychotic experiences were collected using culturally validated measures in a sample of 5927 participants. The weighted prevalence of psychotic symptoms was 9.7%. Exposure to one or more conflict-related events (adj. OR 1.79, 95% CI 1.40-2.31, p<0.001) and loss or injury of a family member or friend through conflict (adj. OR, 1.83, 95% CI 1.42-2.37, p<0.001) were associated with increased odds of reporting psychotic experiences. Psychotic experiences were more common in individuals directly exposed to tsunami disaster (adj. OR, 1.68, 95% CI 1.04-2.73, P=0.035) and in those who had a family member who died or was injured as result of tsunami (adj. OR, 1.42, 95% CI 1.04-1.94, p=0.029). Our findings suggest that psychotic experiences are common in the Sri Lankan population. Exposure to traumatic events in armed conflicts and natural disasters may be important socio-environmental factors in the development of psychotic experiences. PMID:26817400

  9. Sri Lanka.

    PubMed

    1989-12-01

    Sri Lanka has an area of 25,332 square miles and the terrain consists of coastal plains, with hills and mountains in the south central area. Population stands at 16.8 million with a growth rate of 1.6% and ethnic groups include Sinhalese 74%, Tamils 18%, Muslims 7%, and other 1%. The religions are Buddhism, Hinduism, Islam, and Christianity. Languages include Sinhala, Tamil and English, and the literacy rate is 87%. 68.9 years is the average life expectancy and the infant mortality rate is 31/1000. The government is a republic with a president, parliament and a court system. The gross national product is $7.2 billion with a 2.7% growth rate and an inflation rate of 14%. Natural resources include limestone, graphite, mineral sands, gems, and phosphate. Agricultural products include tea, rubber, coconuts, rice, and spices. Industry consists of textiles and garments, chemicals and petroleum products, food processing, wood and wood products, basic metal products, paper and paper products. The British ejected the Dutch in 1796 and set up the crown colony of Ceylon. In 1931 the colony was allowed limited self rule, and in 1948 it became independent. It is a less developed country with a annual average per capita income of $430. In 1977 the government undertook reforms and eliminated price and foreign exchange controls, reduced consumer subsidies and promoted private sector development. The results showed a more than 5% growth rate during the decade and tourism and foreign investment increased. Recently the growth has slowed partly because of a communal conflict, a trade imbalance and serious structural imbalances. PMID:12178023

  10. A feasibility study for the establishment of a national wildlife health centre in Sri Lanka.

    PubMed

    Valeix, S; Lokugalappatti, L G S; Abeynayake, P; Prasad, T; Chandrasiri, A D N; Daniel, S L A; Stephen, C; Leighton, F A

    2011-12-01

    Sri Lanka is a tropical nation within a zoogeographic zone that is at high risk for infectious disease emergence. In 2010, a study was conducted on the feasibility of enhancing capacity in Sri Lanka to manage wildlife diseases through the establishment of a national wildlife health centre. The Canadian Cooperative Wildlife Health Centre was assessed as a potential model for adaptation in Sri Lanka. Interviews and group meetings were conducted with potential key participants from the Sri Lankan Departments of Wildlife Conservation and Animal Production and Health, and the Faculty of Veterinary Medicine and Animal Science of the University of Peradeniya. In addition, site visits were made to potentially participating facilities and the literature on best practices in building scientific capacity was consulted. With strategic enhancements in education and training, additional personnel, improvements in transportation and diagnostic facilities, and central coordination, Sri Lanka appears very well positioned to establish a sustainable wildlife health centre and programme. PMID:22435187

  11. Chemical Characterization of Gallstones: An Approach to Explore the Aetiopathogenesis of Gallstone Disease in Sri Lanka

    PubMed Central

    Weerakoon, Harshi; Navaratne, Ayanthi; Ranasinghe, Shirani; Sivakanesan, Ramaiah; Galketiya, Kuda Banda; Rosairo, Shanthini

    2015-01-01

    Introduction Records on gallstones and associated ailments in Sri Lankan community are scarce, despite frequent detection of gallstone disease. Identification of the chemical composition of gallstones in the local setting is important in defining aetiopathogenic factors which in turn are useful in implementing therapeutic and preventive strategies. This study aimed to describe the chemical composition of gallstones and the socio-demographic factors of a cohort of Sri Lankan patients with gallstone disease. Materials and Methods Data on clinical and socio-demographic factors, and gallstones removed at surgery were collected from patients with cholelithiasis admitted to Teaching Hospital, Peradeniya, Sri Lanka from May 2011 to December 2012. External and cross sectional morphological features of gallstones were recorded by naked eye observation. Compositional analysis was carried out by Fourier Transform Infrared Spectroscopy, X - ray Powder Diffraction, and Atomic Absorption Spectrophotometry. Scanning Electron Microscopy was used to identify the microstructure of gallstones. Results Data of 102 patients were analyzed. Of them majority (n = 77, 76%) were females with a female: male ratio of 3:1. Mean age of the study group was 46.1±11.6 years. All the patients had primary gallbladder stones. According to the physical and chemical analysis, majority (n = 54, 53%) were pigment gallstones followed by mixed cholesterol gallstones (n = 38, 37%). Only 10 (9%) had pure cholesterol gallstones. Calcium bilirubinate, calcium carbonate and calcium phosphate were the commonest calcium salts identified in pigment gallstones and core of mixed cholesterol gallstones. Conclusion Presence of a pigment nidus in gallstones is a common feature in majority of Sri Lankan patients denoting the possible role of elevated unconjugated bilirubin in bile on the pathogenesis of GS. Hence it is imperative to explore this further to understand the aetiopathogenesis of GS among Sri Lankans. PMID

  12. A critical review of environmental impact statements in Sri Lanka with particular reference to ecological impact assessment.

    PubMed

    Samarakoon, Miriya; Rowan, John S

    2008-03-01

    This article critically reviews environmental assessment (EA) practices in Sri Lanka, with a particular focus on ecology. An overview is provided of the domestic and international influences which have shaped the administrative process which is currently a two-tiered scheme. An Initial Environmental Examination (IEE) provides a preliminary screening tool, prior to the requirement for a full Environmental Impact Assessment (EIA). A comprehensive survey of Sri Lankan national archives showed that 463 EAs were completed in the period 1981-2005, with the bulk of these in the more populated Western and North Western Provinces. Two-thirds were IEE surveys, while the remaining third advanced to full EIA. A representative sample of 130 EAs (both IEEs and full EIAs) spanning a broad range of project types, scales, and environmental settings was selected to evaluate the quality of the ecological investigations within the published environmental impact statements (EISs). These were assigned into five classes of "explanatory power", on the basis of their scientific content in relation to survey, analysis, and reporting of ecological interests. Within most EISs, the ecological impact assessment (EcIA) was restricted to the lowest two categories of ecological assessment, i.e., tokenistic presentation of reconnaissance-level species lists without further analysis of the development implications for individual organisms or communities. None of the assessments reviewed provided statistically rigorous analysis, which would be required if ecological impact studies are to include quantitative and testable predictions of impact, which could then be followed up by appropriate post-impact monitoring programs. Attention to key local issues such as biodiversity or ecosystem services, which also have strong social dimensions in the developing world, was also notably underrepresented. It was thus concluded that despite the existence of a sound legislative framework in Sri Lanka, the analysis

  13. A Critical Review of Environmental Impact Statements in Sri Lanka with Particular Reference to Ecological Impact Assessment

    NASA Astrophysics Data System (ADS)

    Samarakoon, Miriya; Rowan, John S.

    2008-03-01

    This article critically reviews environmental assessment (EA) practices in Sri Lanka, with a particular focus on ecology. An overview is provided of the domestic and international influences which have shaped the administrative process which is currently a two-tiered scheme. An Initial Environmental Examination (IEE) provides a preliminary screening tool, prior to the requirement for a full Environmental Impact Assessment (EIA). A comprehensive survey of Sri Lankan national archives showed that 463 EAs were completed in the period 1981 2005, with the bulk of these in the more populated Western and North Western Provinces. Two-thirds were IEE surveys, while the remaining third advanced to full EIA. A representative sample of 130 EAs (both IEEs and full EIAs) spanning a broad range of project types, scales, and environmental settings was selected to evaluate the quality of the ecological investigations within the published environmental impact statements (EISs). These were assigned into five classes of “explanatory power”, on the basis of their scientific content in relation to survey, analysis, and reporting of ecological interests. Within most EISs, the ecological impact assessment (EcIA) was restricted to the lowest two categories of ecological assessment, i.e., tokenistic presentation of reconnaissance-level species lists without further analysis of the development implications for individual organisms or communities. None of the assessments reviewed provided statistically rigorous analysis, which would be required if ecological impact studies are to include quantitative and testable predictions of impact, which could then be followed up by appropriate post-impact monitoring programs. Attention to key local issues such as biodiversity or ecosystem services, which also have strong social dimensions in the developing world, was also notably underrepresented. It was thus concluded that despite the existence of a sound legislative framework in Sri Lanka, the

  14. A cost effectiveness analysis of the preferred antidotes for acute paracetamol poisoning patients in Sri Lanka

    PubMed Central

    2012-01-01

    Background Acute paracetamol poisoning is a rapidly increasing problem in Sri Lanka. The antidotes are expensive and yet no health economic evaluation has been done on the therapy for acute paracetamol poisoning in the developing world. The aim of this study is to determine the cost effectiveness of using N-acetylcysteine over methionine in the management of acute paracetamol poisoning in Sri Lanka. Methods Economic analysis was applied using public healthcare system payer perspective. Costs were obtained from a series of patients admitted to the National Hospital of Sri Lanka with a history of acute paracetamol overdose. Evidence on effectiveness was obtained from a systematic review of the literature. Death due to hepatotoxicity was used as the primary outcome of interest. Analysis and development of decision tree models was done using Tree Age Pro 2008. Results An affordable treatment threshold of Sri Lankan rupees 1,537,120/death prevented was set from the expected years of productive life gained and the average contribution to GDP. A cost-minimisation analysis was appropriate for patients presenting within 10 hours and methionine was the least costly antidote. For patients presenting 10-24 hours after poisoning, n-acetylcysteine was more effective and the incremental cost effectiveness ratio of Sri Lankan rupees 316,182/life saved was well under the threshold. One-way and multi-way sensitivity analysis also supported methionine for patients treated within 10 hours and n-acetylcysteine for patients treated within 10-24 hours as preferred antidotes. Conclusions Post ingestion time is an important determinant of preferred antidotal therapy for acute paracetamol poisoning patients in Sri Lanka. Using n-acetylcysteine in all patients is not cost effective. On economic grounds, methionine should become the preferred antidote for Sri Lankan patients treated within 10 hours of the acute ingestion and n-acetylcysteine should continue to be given to patients treated

  15. The use and abuse of female domestic workers from Sri Lanka in Lebanon.

    PubMed

    Abu-habib, L

    1998-03-01

    Women who migrate from Sri Lanka to become domestic workers in Lebanon face gender, class, and race discrimination that often results in abuse, yet the predicament of these women is largely ignored by local and international humanitarian and human rights agencies. Public consciousness about the plight of Asian domestic workers in the Persian Gulf region was raised in 1990 when domestic workers were repatriated in the wake of the Gulf War. In Lebanon, nearly half of the work permits granted to foreigners in 1997 were to women from Sri Lanka. This migration began in the 1970s and is sanctioned by the Sri Lanka government because of the economic benefits accruing from wages sent home by these women. Lebanese families procure domestic positions through an employment agency that arranges transportation and entry for the Sri Lankan women. These women, especially minors, often have to bribe Sri Lankan government agents to falsify travel documents. Upon arrival in Lebanon, the women have no support systems or job security. Most employment contracts last 3 years and pay $100/month with no benefits or protection from local labor laws. Domestic workers are made vulnerable by employers who withhold salaries or travel documents. Upon return to Sri Lanka, former domestic workers face social disapproval and marital problems. To redress this situation, the governments of sending and receiving countries must take action to protect female migrant workers, and nongovernmental organizations must publicize the plight of these women and take action to address the abuses they face. PMID:12321536

  16. Knowledge, Attitudes, and Practices on Lifestyle and Cardiovascular Risk Factors Among Metabolic Syndrome Patients in an Urban Tertiary Care Institute in Sri Lanka

    PubMed Central

    Amarasekara, Priyanwada; de Silva, Angela; Swarnamali, Hasinthi; Senarath, Upul; Katulanda, Prasad

    2016-01-01

    Metabolic syndrome (MetS) is a significant predictor of cardiovascular diseases (CVDs). A pretested questionnaire was used to assess knowledge, attitudes, and practice (KAP) of CVD and its risks among Sri Lankan urban adults (35–55 years) with MetS. KAP scores were predefined as high, moderate, and low. Of the participants (n = 423), 13% were males and 87% were females. Attitudes scores were high among this population, though their knowledge and practices scores on CVD risk factors were moderate. Participants with high mean knowledge scores had significantly lower waist circumference (WC) and showed a trend toward reduced fasting blood glucose levels. Participants with high practice scores had significantly lower BMI and WC, which signify that better knowledge and practices are associated with decrease in CVD risk markers in these patients. The study reveals that urban MetS patients have a moderate knowledge and practice score, though their attitude score is high regarding CVD risk factors. PMID:26512029

  17. Growing Pains: The Impact of Disaster-Related and Daily Stressors on the Psychological and Psychosocial Functioning of Youth in Sri Lanka

    ERIC Educational Resources Information Center

    Fernando, Gaithri A.; Miller, Kenneth E.; Berger, Dale E.

    2010-01-01

    Daily stressors may mediate the relation between exposure to disaster-related stressors and psychological and psychosocial distress among youth in disaster-affected countries. A sample of 427 Sri Lankan Sinhalese, Tamil, and Muslim youth (mean age = 14.5) completed a survey with measures of exposure to disaster-related stressors and daily…

  18. Girls' identity formation in the changing social structure of Sri Lanka.

    PubMed

    de Silva, S; Stiles, D A; Gibbons, J L; Gibbon, J L

    1992-06-01

    Adolescent girls (N = 118) from diverse social backgrounds in Sri Lanka described their views of womanhood. Qualities of the ideal woman considered most important were kindness and honesty, liking children, intelligence, and having a good job. Although the traditional role of the Sri Lankan woman is that of homemaker, most girls in the study (55%) drew the ideal woman working outside the home, often as a teacher or a doctor. Nevertheless, adolescent girls emphasized traditional qualities of the woman at both work and home as self-sacrificing and serving others. PMID:1512588

  19. Perfluorinated organic compounds in human blood serum and seminal plasma: a study of urban and rural tea worker populations in Sri Lanka.

    PubMed

    Guruge, Keerthi S; Taniyasu, Sachi; Yamashita, Nobuyoshi; Wijeratna, Sumedha; Mohotti, Keerthi M; Seneviratne, Harsha R; Kannan, Kurunthachalam; Yamanaka, Noriko; Miyazaki, Shigeru

    2005-04-01

    Concentrations and accumulation of 13 fluorinated organic compounds (FOCs) in human sera and seminal plasma were measured in an Asian developing country, Sri Lanka. Six of the FOCs, PFOS (perfluorooctanesulfonate), PFHS (perfluorohexanesulfonate), PFUnA (perfluoroundecanoic acid), PFDA (perfluorodecanoic acid), PFNA (perfluorononanoic acid) and PFOA (perfluorooctanoic acid), were detected in all of the sera samples. Measurable quantities of two main perfluorosulfonates, PFOS and PFHS, were found in all seminal plasma samples. The detection frequency of the predominant perfluoroalkylcarboxylate, PFOA, in seminal plasma was >70%. Accumulation of PFOS in sera was significantly positively correlated with PFOA, PFHS and PFNA. Positive linear regressions were also found between PFNA and PFUnA and PFNA and PFDA suggesting that these compounds may have a similar origin of exposure and accumulation. Significantly positive associations were observed for partitioning of both PFOS and PFNA between sera and seminal plasma. The accumulation of FOCs was not significantly different in sera from Colombo (urban population) and Talawakele (rural conventional tea workers). However, the Haldummulla population (rural organic tea workers) had relatively lower exposure to FOCs compared to the other two groups, urban and rural conventional tea workers. Concentrations of FOCs in Sri Lanka were similar to those reported for industrialized countries suggesting that human exposure to such chemicals is widespread even in developing countries. The novel finding of FOCs in human seminal plasma implies that further studies are needed to determine whether long-term exposure in humans can result in reproductive impairments. PMID:15798805

  20. Religious leaders as potential advocates for HIV/AIDS prevention among the general population in Sri Lanka.

    PubMed

    Kanda, Koji; Jayasinghe, Ananda; Silva, K Tudor; Priyadarshani, N G W; Delpitiya, N Y; Obayashi, Yoshihide; Arai, Asuna; Gamage, Chandika D; Tamashiro, Hiko

    2013-01-01

    Religious leaders in Sri Lanka may have a high potential of contributing to HIV/AIDS prevention among the general public because of their social status. In order to assess their current HIV/AIDS-related knowledge and attitude and the possibility of becoming community advocates of HIV/AIDS prevention, we conducted a questionnaire survey among Buddhist, Hindu, Muslim and Christian leaders in Sri Lanka in 2009. There were limited correct responses about HIV/AIDS-related knowledge and attitudes toward people living with HIV/AIDS (PLHIV), and information regarding condoms, HIV testing and counselling were poorly understood. Although a condom was less acceptable as a part of HIV/AIDS prevention, they were willing to learn more about HIV/AIDS and expressed support for both PLHIV and HIV prevention activities. Their experiences, preparedness and willingness of HIV prevention activities were associated with age, knowledge and/or religious background. In conclusion, intensive and systematic learning opportunities should be provided to equip the religious leaders with overall HIV/AIDS knowledge to become key players for HIV/AIDS prevention in their communities. PMID:23205515

  1. A Historical Analysis of the Relationship Between Rice Production and PDSI Values in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Jacobi, J. H.; Hornberger, G. M.

    2011-12-01

    As world population grows, there are ever increasing demands being placed on the food production systems throughout the world. Climate change is complicating these stressors even further through more frequent severe weather events. In the developing world, where there are fewer resources to mitigate the effects of climate change, the combination of these two factors can have drastic consequences. In Sri Lanka, farmers in major rice production areas of the country are already struggling to produce enough rice, a staple food of the local diet, and a severe wet or dry spell could be ruinous. Faced with a changing climate and a growing demand for rice, it is important to be able to anticipate how climatic changes will affect rice production. By examining how extreme wet and dry spells have historically affected rice production, decision makers may be better able to predict and prepare for potential food shortages. We conducted an analysis of historic temperature, precipitation, and rice production statistics in order to determine the effects of extreme wet and dry spells on rice production. We also created a timeline of major developments in Sri Lankan agriculture in order to compare effects on rice production due to changes in agricultural practices with meteorological changes. Historical temperature and precipitation data were used to calculate the Palmer Drought Severity Index (PDSI) for a number of stations distributed throughout the Mahaweli river basin. The basin, the largest in the country, contains three different climatic regions - dry, intermediate, and wet - that all receive different amounts of annual precipitation. The PDSI values were used to quantify drought and wetness during the Yala (April-September) and Maha (October-March) growing seasons. Analysis of historical PDSI values, agricultural advances, and rice production statistics shows great promise for anticipating and mitigating future food shortages.

  2. Nephrotoxic contaminants in drinking water and urine, and chronic kidney disease in rural Sri Lanka.

    PubMed

    Rango, Tewodros; Jeuland, Marc; Manthrithilake, Herath; McCornick, Peter

    2015-06-15

    Chronic kidney disease of unknown ("u") cause (CKDu) is a growing public health concern in Sri Lanka. Prior research has hypothesized a link with drinking water quality, but rigorous studies are lacking. This study assesses the relationship between nephrotoxic elements (namely arsenic (As), cadmium (Cd), lead (Pb), and uranium (U)) in drinking water, and urine samples collected from individuals with and/or without CKDu in endemic areas, and from individuals without CKDu in nonendemic areas. All water samples - from a variety of source types (i.e. shallow and deep wells, springs, piped and surface water) - contained extremely low concentrations of nephrotoxic elements, and all were well below drinking water guideline values. Concentrations in individual urine samples were higher than, and uncorrelated with, those measured in drinking water, suggesting potential exposure from other sources. Mean urinary concentrations of these elements for individuals with clinically diagnosed CKDu were consistently lower than individuals without CKDu both in endemic and nonendemic areas. This likely stems from the inability of the kidney to excrete these toxic elements via urine in CKDu patients. Urinary concentrations of individuals were also found to be within the range of reference values measured in urine of healthy unexposed individuals from international biomonitoring studies, though these reference levels may not be safe for the Sri Lankan population. The results suggest that CKDu cannot be clearly linked with the presence of these contaminants in drinking water. There remains a need to investigate potential interactions of low doses of these elements (particularly Cd and As) with other risk factors that appear linked to CKDu, prior to developing public health strategies to address this illness. PMID:25782025

  3. An Overview of Meat Industry in Sri Lanka: A Comprehensive Review

    PubMed Central

    Alahakoon, Amali U.; Jo, Cheorun

    2016-01-01

    Livestock is considered as one of the most important segments in agriculture since animal husbandry was practiced for centuries as a backyard system by rural families. Livestock plays as a powerful tool in rural development where meat industry contributes a dominant part. Meat and meat products become a vital component in the diet, which had been one of the main protein sources traditionally as well. The development in the livestock and meat industry of Sri Lanka basically depends upon religious, cultural, and economic factors. There is a growing demand for processed meat products in Sri Lankan urban culture and several large scale processors entered the business during the past few decades. The consumption of meat and meat products shows an upward trend in Sri Lanka during the last decade and is anticipated to increase further in future. The growth potential of the local meat industry is considerably high owing to the improvement of the market and consumer perception. The present status, trends, and future prospects for the Sri Lankan meat industry with respect to production, consumption, processing, marketing, and improvement are discussed in this review. PMID:27194920

  4. An Overview of Meat Industry in Sri Lanka: A Comprehensive Review.

    PubMed

    Alahakoon, Amali U; Jo, Cheorun; Jayasena, Dinesh D

    2016-01-01

    Livestock is considered as one of the most important segments in agriculture since animal husbandry was practiced for centuries as a backyard system by rural families. Livestock plays as a powerful tool in rural development where meat industry contributes a dominant part. Meat and meat products become a vital component in the diet, which had been one of the main protein sources traditionally as well. The development in the livestock and meat industry of Sri Lanka basically depends upon religious, cultural, and economic factors. There is a growing demand for processed meat products in Sri Lankan urban culture and several large scale processors entered the business during the past few decades. The consumption of meat and meat products shows an upward trend in Sri Lanka during the last decade and is anticipated to increase further in future. The growth potential of the local meat industry is considerably high owing to the improvement of the market and consumer perception. The present status, trends, and future prospects for the Sri Lankan meat industry with respect to production, consumption, processing, marketing, and improvement are discussed in this review. PMID:27194920

  5. Chronic kidney disease of uncertain aetiology: adding vital piece of information to the national project team report of Sri Lanka.

    PubMed

    Jayalal, T B Ananda

    2015-01-01

    In a recent study published by the National Project Team on chronic kidney diseases of unknown origin in Sri Lanka, identified cadmium as a major risk factor but strong conclusions were not made as the identified environmental toxins were within the permissible levels.Sri Lankan food consumption pattern is different so that approach of total exposure of cadmium by food and water been calculated. Such calculation point out that total exposure of cadmium exceed the provisional tolerable weekly intake determined by international agencies. PMID:26701260

  6. Saw-scaled viper bites in Sri Lanka: is it a different subspecies? Clinical evidence from an authenticated case series.

    PubMed

    Gnanathasan, Ariaranee; Rodrigo, Chaturaka; Peranantharajah, Thambipillai; Coonghe, Anthonia

    2012-02-01

    The saw-scaled viper (SSV) (Echis carinatus) is considered to be a highly venomous snake in Sri Lanka despite any published clinical justification. Being a rarity, the clinical profile of SSV bites is not well established in Sri Lanka. We report a series of 48 (n-48) SSV bites from the Northern Province of Sri Lanka. The majority (65%) of victims had evidence of local envenoming at the site of the bite; however, 29% showed spontaneous bleeding and 71% had coagulopathy. There were no deaths in the series. The envenoming was mild in contrast to the mortality and significant morbidity associated with SSV bites in West Africa and some parts of India. These observations need to be further explored with laboratory studies to identify the venom components, study of morphological characteristics, and genetic profiling of the Sri Lankan SSV to see if it is different from the subspecies found elsewhere. PMID:22302858

  7. Stabilising a victor's peace? Humanitarian action and reconstruction in eastern Sri Lanka.

    PubMed

    Goodhand, Jonathan

    2010-10-01

    This paper focuses on the 'Sri Lankan model' of counter-insurgency and stabilisation and its implications for humanitarian and development actors. The Sri Lanka case shows that discourses, policies and practices associated with 'stabilisation' are not confined to 'fragile state' contexts in which there is heavy (and often militarised) international engagement--even though exemplars such as Afghanistan and Iraq have tended to dominate debates on this issue. Rather than being a single template, the 'stabilisation agenda' takes on very different guises in different contexts, presenting quite specific challenges to humanitarian and development actors. This is particularly true in settings like Sri Lanka, where there is a strong state, which seeks to make aid 'coherent' with its own vision of a militarily imposed political settlement. Working in such environments involves navigating a highly-charged domestic political arena, shaped by concerns about sovereignty, nationalism and struggles for legitimacy. PMID:20846349

  8. Transitions in ancient inland freshwater resource management in Sri Lanka affect biota and human populations in and around coastal lagoons.

    PubMed

    Dahdouh-Guebas, F; Hettiarachchi, S; Lo Seen, D; Batelaan, O; Sooriyarachchi, S; Jayatissa, L P; Koedam, N

    2005-03-29

    The increasing anthropogenic pressure on natural environments results in impacts that affect tropical forest areas and their biodiversity. Adverse impacts on terrestrial and oceanic environments often compound in the intertidal area, where mangrove forest ecosystems thrive. In tropical coastal areas of many developing countries where people depend on wood and other mangrove forest products and services, forest degradation leads to socioeconomic problems. At the same time, increasing freshwater needs in these areas are expected to cause additional problems. On the basis of remote sensing and ground truthing complemented by colonial archival material from the Dutch East India Company (1602-1800), we report that changes to the historic system of inland freshwater management have increased dramatically in recent times. Hydrological changes, such as interbasin transfers, have resulted in a qualitative ecological and socioeconomic degradation in three coastal lagoons in southern Sri Lanka. Variations in river hydrology have caused changes in the areas suitable as mangrove habitat and, thus, have resulted in an altered distribution. However, increases in mangrove area can mask the degradation of the site in terms of floristic composition, significance of the species, and biodiversity (this effect is termed "cryptic ecological degradation"). It is important that such changes be carefully monitored to ensure biological and socioeconomic sustainability. PMID:15797030

  9. Antivenom for snakebite envenoming in Sri Lanka: the need for geographically specific antivenom and improved efficacy.

    PubMed

    Keyler, D E; Gawarammana, I; Gutiérrez, J M; Sellahewa, K H; McWhorter, K; Malleappah, R

    2013-07-01

    Sri Lanka is a tropical developing island nation that endures significant economic and medical burden as a result of snakebite envenomation, having not only a high prevalence of envenomations, but also one of the highest incidence rates (200 snakebites/100,000 people/year) of venomous snakebite in the world (Kasturiratne et al., 2005). Ironically, the very snakes responsible for this human morbidity and mortality are a valuable biomedical and ecological national resource, despite the medical and economic consequences of envenomation. Currently, no snake antivenom is produced using venoms from native Sri Lankan snakes as immunogens, and there is a true need for an efficacious Sri Lanka, poly-specific snake antivenom. An approach to fulfilling this need via combining the scientific, technological and economical resources from Costa Rica and the United States with the knowledge and talent of Sri Lankan official governmental agencies, legal counsels, environmental, medical and veterinary academic institutions, and religious and cultural leaders has been initiated, coordinated and funded by Animal Venom Research International (AVRI), a nonprofit charity. This bridging of nations and the cooperative pooling of their resources represents a potential avenue for antivenom development in a developing country that suffers the consequences of few specific resources for the medical management of venomous snakebite. The desired final outcome of such an endeavor for Sri Lanka is, most importantly, improved medical outcomes for snakebite patients, with enhanced and expanded science and technology relating to snake venoms and antivenoms, and the collateral benefits of reduced economic cost for the country. PMID:23454626

  10. Insecticide resistance and, efficacy of space spraying and larviciding in the control of dengue vectors Aedes aegypti and Aedes albopictus in Sri Lanka.

    PubMed

    Karunaratne, S H P P; Weeraratne, T C; Perera, M D B; Surendran, S N

    2013-09-01

    Unprecedented incidence of dengue has been recorded in Sri Lanka in recent times. Source reduction and use of insecticides in space spraying/fogging and larviciding, are the primary means of controlling the vector mosquitoes Aedes aegypti and Ae. albopictus in the island nation. A study was carried out to understand insecticide cross-resistance spectra and mechanisms of insecticide resistance of both these vectors from six administrative districts, i.e. Kandy, Kurunegala, Puttalam, Gampaha, Ratnapura and Jaffna, of Sri Lanka. Efficacy of the recommended dosages of frequently used insecticides in space spraying and larviciding in dengue vector control programmes was also tested. Insecticide bioassay results revealed that, in general, both mosquito species were highly resistant to DDT but susceptible to propoxur and malathion except Jaffna Ae. aegypti population. Moderate resistance to malathion shown by Jaffna Ae. aegypti population correlated with esterase and malathion carboxylesterase activities of the population. High levels of acetylcholinesterase (AChE) insensitivity in the absence of malathion and propoxur resistance may be due to non-synaptic forms of AChE proteins. Moderate pyrethroid resistance in the absence of high monooxygenase levels indicated the possible involvement of 'kdr' type resistance mechanism in Sri Lankan dengue vectors. Results of the space spraying experiments revealed that 100% mortality at a 10 m distance and >50% mortality at a 50 m distance can be achieved with malathion, pesguard and deltacide even in a ground with dense vegetation. Pesguard and deltacide spraying gave 100% mortality up to 50 m distance in open area and areas with little vegetation. Both species gave >50% mortalities for deltacide at a distance of 75 m in a dense vegetation area. Larval bioassays conducted in the laboratory showed that a 1 ppm temephos solution can maintain a larval mortality rate of 100% for ten months, and the mortality rate declined to 0% in the

  11. Additional perspectives on chronic kidney disease of unknown aetiology (CKDu) in Sri Lanka – lessons learned from the WHO CKDu population prevalence study

    PubMed Central

    2014-01-01

    The recent emergence of an apparently new form of chronic kidney disease of unknown aetiology (CKDu) has become a serious public health crisis in Sri Lanka. CKDu is slowly progressive, irreversible, and asymptomatic until late stages, and is not attributable to hypertension, diabetes, or other known aetiologies. In response to the scope and severity of the emerging CKDu health crisis, the Sri Lanka Ministry of Health and the World Health Organization initiated a collaborative research project from 2009 through 2012 to investigate CKDu prevalence and aetiology. The objective of this paper is to discuss the recently published findings of this investigation and present additional considerations and recommendations that may enhance subsequent investigations designed to identify and understand CKDu risk factors in Sri Lanka or other countries. PMID:25069485

  12. Content Analysis of Food and Beverages Advertisements Targeting Children and Adults on Television in Sri Lanka

    PubMed Central

    Prathapan, Shamini; Wijewardena, Kumudu; Low, Wah Yun

    2016-01-01

    Introduction Food marketing is one of the main factors in the increase in childhood obesity. The objective is to compare the strategies used for promotion of food and beverages advertisements on Sri Lankan television for children and adults. Method Among 16 analog television channels in Sri Lanka, 50% of the channels were selected randomly after stratifying according to language. Recording was during weekdays and weekends. In total, 95 different food and beverages advertisements were analyzed irrespective of the channel. Results Among all food and beverages–related advertisements, 78% were child focused, and among these 74% claimed health benefits. A statistically significant difference was found in terms of implications related to nutrition or health (P < .05). None of the advertisements contained disclaimers. Conclusion and recommendations The Ministry of Health needs to pursue all food and beverages–focused advertisements for policy formulation and implementation. PMID:26658325

  13. Ethnic models of fertility behaviour in Sri Lanka.

    PubMed

    Abeykoon, A T

    1987-12-01

    Ethnic differences in fertility behavior confirm that socioeconomic variables exert a strong influence on demographic and family planning variables in developing countries such as Sri Lanka. To explain the effects of ethnicity on fertility behavior, predictive path models were developed for the 4 ethnic groups in Sri Lanka--Sinhalese, Tamils, Moors, and Indian Tamils. The path models used in developing predictive models utilized a series of ordinary least squares regression equations. The data were drawn from the 1982 Contraceptive Prevalence Survey. Current residence had direct negative effects on education for all 4 ethnic groups, with women in urban areas achieving higher levels of education than those in rural or estate areas; current residence further had a direct positive effect on husband's occupation, with higher socioeconomic status reported for women from urban areas. Age at marriage--the most important determinant of children ever born-- had strong negative effects on fertility for all ethnic groups, but the effect was most marked among Sri Lankan Tamils. Contraceptive knowledge had the same effect on the effectiveness of contraceptive use in all ethnic groups, suggesting that informational campaigns would enhance the decline of fertility in the country as a whole. 47% of the variance in additional children desired was explained by children ever born (negative effect), ideal family size (positive effect), and child mortality (positive effect). 11% of the variance in contraceptive usage was contributed by education (positive effect), children ever born (positive effect), and husband's occupation (negative effect), while 24% of the variance in effectiveness of contraceptive use was explained by additional children wanted (negative effect) and contraceptive knowledge (positive effect). Overall, these findings suggest that socioeconomic assimilation, with consequent higher levels of education, will facilitate more modern behaviors such as later age at

  14. Using Non-Personal Computers for eLearning: Sri Lankan Experience

    ERIC Educational Resources Information Center

    Liyanagunawardena, Tharindu R.; Adams, Andrew A.; Rassool, Naz; Williams, Shirley A.

    2013-01-01

    Communal Internet access facilities or telecentres are considered a good way to provide connectivity to people who do not possess home connectivity. Attempts are underway to utilize telecentres as eLearning centres providing access to learning materials to students who would otherwise not be able to take up eLearning. This paper reports on the…

  15. Post-coital contraceptive activity of crude extracts of Sri Lankan marine red algae.

    PubMed

    Ratnasooriya, W D; Premakumara, G A; Tillekeratne, L M

    1994-09-01

    This study investigates the potential of marine red algae as a source for post-coital contraceptive agents using three varieties: Gracilaria corticata, Gelidiella acerosa and Jania sp. Methanol: methylene chloride (1:1) extracts of these red algae were made and were orally administered (500 or 1000 mg/kg/day) to female rats from day 1 to day 7 of pregnancy. The higher dose of Gracilaria corticata and both doses of Gelidiella acerosa extracts produced significant post-coital contraceptive activities without any marked side effects. Furthermore, the post-coital contraceptive activity of the latter extract was dose-dependent. On the other hand, extract made from Jania sp. had no significant post-coital contraceptive action. The post-coital contraceptive activity of Gracilaria corticata was due to enhanced pre-implantation loss and of Gelidiella acerosa was due to elevated post-implantation loss. These findings indicate that marine red algae is a useful source to be harvested for potential post-coital contraceptive drugs. PMID:7805379

  16. Knowledge Use in the Construction of Geometry Proof by Sri Lankan Students

    ERIC Educational Resources Information Center

    Chinnappan, Mohan; Ekanayake, Madduma B.; Brown, Christine

    2012-01-01

    Within the domain of geometry, proof and proof development continues to be a problematic area for students. Battista (2007) suggested that the investigation of knowledge components that students bring to understanding and constructing geometry proofs could provide important insights into the above issue. This issue also features prominently in the…

  17. Impacts of the 2004 tsunami on groundwater resources in Sri Lanka

    USGS Publications Warehouse

    Illangasekare, T.; Tyler, S.W.; Clement, T.P.; Villholth, K.G.; Perera, A.P.G.R.L.; Obeysekera, J.; Gunatilaka, A.; Panabokke, C.R.; Hyndman, D.W.; Cunningham, K.J.; Kaluarachchi, J.J.; Yeh, W.W.-G.; Van Genuchten, M. T.; Jensen, K.

    2006-01-01

    The 26 December 2004 tsunami caused widespread destruction and contamination of coastal aquifers across southern Asia. Seawater filled domestic open dug wells and also entered the aquifers via direct infiltration during the first flooding waves and later as ponded seawater infiltrated through the permeable sands that are typical of coastal aquifers. In Sri Lanka alone, it is estimated that over 40,000 drinking water wells were either destroyed or contaminated. From February through September 2005, a team of United States, Sri Lankan, and Danish water resource scientists and engineers surveyed the coastal groundwater resources of Sri Lanka to develop an understanding of the impacts of the tsunami and to provide recommendations for the future of coastal water resources in south Asia. In the tsunami-affected areas, seawater was found to have infiltrated and mixed with fresh groundwater lenses as indicated by the elevated groundwater salinity levels. Seawater infiltrated through the shallow vadose zone as well as entered aquifers directly through flooded open wells. Our preliminary transport analysis demonstrates that the intruded seawater has vertically mixed in the aquifers because of both forced and free convection. Widespread pumping of wells to remove seawater was effective in some areas, but overpumping has led to upconing of the saltwater interface and rising salinity. We estimate that groundwater recharge from several monsoon seasons will reduce salinity of many sandy Sri Lankan coastal aquifers. However, the continued sustainability of these small and fragile aquifers for potable water will be difficult because of the rapid growth of human activities that results in more intensive groundwater pumping and increased pollution. Long-term sustainability of coastal aquifers is also impacted by the decrease in sand replenishment of the beaches due to sand mining and erosion. Copyright 2006 by the American Geophysical Union.

  18. Molecular mechanisms of β-lactam resistance in carbapenemase-producing Klebsiella pneumoniae from Sri Lanka.

    PubMed

    Hall, Jarrad M; Corea, Enoka; Sanjeewani, H D Anusha; Inglis, Timothy J J

    2014-08-01

    Carbapenemases are increasingly important antimicrobial resistance determinants. Little is known about the carbapenem resistance mechanisms in Sri Lanka. We examined 22 carbapenem-resistant Klebsiella pneumoniae from Sri Lanka to determine their β-lactam resistance mechanisms. The predominant resistance mechanisms we detected in this study were OXA-181, NDM-1 carbapenemases and extended-spectrum β-lactamase CTX-M-15. All isolates were then genotyped by pulsed-field gel electrophoresis, variable-number tandem repeat sequence analysis and multilocus sequence typing, and seven distinct genotypes were observed. Five OXA-181-positive Klebsiella pneumoniae isolates were genotypically related to an isolate of Indian origin. Multilocus sequence typing found that these related isolates belong to ST-14, which has been associated with dissemination of OXA-181 from the Indian subcontinent. Other genotypes we discovered were ST-147 and ST-340, also associated with intercontinental spread of carbapenemases of suspected subcontinental origin. The major porin genes ompK35 and ompK36 from these isolates had insertions, deletions and substitutions. Some of these were exclusive to strains within single pulsotypes. We detected one ompK36 variant, ins AA134-135GD, in six ST-14- and six ST-147, blaOXA-181-positive isolates. This porin mutation was an independent predictor of high-level meropenem resistance in our entire Sri Lankan isolate collection (P=0.0030). Analysis of the Sri Lankan ST-14 and ST-147 ins AA134-135GD-positive isolates found ST-14 was more resistant to meropenem than other isolates (mean MIC: 32±0 µg ml(-1) and 20±9.47 µg ml(-1), respectively, P=0.0277). The likely international transmission of these carbapenem resistance determinants highlights the need for regional collaboration and prospective surveillance of carbapenem-resistant Enterobacteriaceae. PMID:24855071

  19. Chikungunya as a Cause of Acute Febrile Illness in Southern Sri Lanka

    PubMed Central

    Reller, Megan E.; Akoroda, Ufuoma; Nagahawatte, Ajith; Devasiri, Vasantha; Kodikaarachchi, Wasantha; Strouse, John J.; Chua, Robert; Hou, Yan'an; Chow, Angelia; Sessions, October M.; Østbye, Truls; Gubler, Duane J.; Woods, Christopher W.; Bodinayake, Champica

    2013-01-01

    Background Chikungunya virus (CHIKV) re-emerged in Sri Lanka in late 2006 after a 40-year hiatus. We sought to identify and characterize acute chikungunya infection (CHIK) in patients presenting with acute undifferentiated febrile illness in unstudied rural and semi-urban southern Sri Lanka in 2007. Methodology/Principal Findings We enrolled febrile patients ≥ 2 years of age, collected uniform epidemiologic and clinical data, and obtained serum samples for serology, virus isolation, and real-time reverse-transcriptase PCR (RT-PCR). Serology on paired acute and convalescent samples identified acute chikungunya infection in 3.5% (28/797) patients without acute dengue virus (DENV) infection, 64.3% (18/28) of which were confirmed by viral isolation and/or real-time RT-PCR. No CHIKV/DENV co-infections were detected among 54 patients with confirmed acute DENV. Sequencing of the E1 coding region of six temporally distinct CHIKV isolates (April through October 2007) showed that all isolates posessed the E1-226A residue and were most closely related to Sri Lankan and Indian isolates from the same time period. Except for more frequent and persistent musculoskeletal symptoms, acute chikungunya infections mimicked DENV and other acute febrile illnesses. Only 12/797 (1.5%) patients had serological evidence of past chikungunya infection. Conclusions/Significance Our findings suggest CHIKV is a prominent cause of non-specific acute febrile illness in southern Sri Lanka. PMID:24312651

  20. Field Survey of Tsunami Effects in Sri Lanka due to the Sumatra-Andaman Earthquake of December 26, 2004

    NASA Astrophysics Data System (ADS)

    Inoue, Shusaku; Wijeyewickrema, Anil C.; Matsumoto, Hiroyuki; Miura, Hiroyuki; Gunaratna, Priyantha; Madurapperuma, Manoj; Sekiguchi, Toru

    2007-03-01

    The December 26, 2004 Sumatra-Andaman earthquake that registered a moment magnitude (M w ) of 9.1 was one of the largest earthquakes in the world since 1900. The devastating tsunami that resulted from this earthquake caused more casualties than any previously reported tsunami. The number of fatalities and missing persons in the most seriously affected countries were Indonesia - 167,736, Sri Lanka - 35,322, India - 18,045 and Thailand - 8,212. This paper describes two field visits to assess tsunami effects in Sri Lanka by a combined team of Japanese and Sri Lankan researchers. The first field visit from December 30, 2004 January 04, 2005 covered the western and southern coasts of Sri Lanka including the cities of Moratuwa, Beruwala, Bentota, Pereliya, Hikkaduwa, Galle, Talpe, Matara, Tangalla and Hambantota. The objectives of the first field visit were to investigate the damage caused by the tsunami and to obtain eyewitness information about wave arrival times. The second field visit from March 10 18, 2005 covered the eastern and southern coasts of Sri Lanka and included Trincomalee, Batticaloa, Arugam Bay, Yala National Park and Kirinda. The objectives of the second visit were mainly to obtain eyewitness information about wave arrival times and inundation data, and to take relevant measurements using GPS instruments.

  1. Isolation and Molecular Characterization of Entamoeba nuttalli Strains Showing Novel Isoenzyme Patterns from Wild Toque Macaques in Sri Lanka.

    PubMed

    Tachibana, Hiroshi; Yanagi, Tetsuo; Feng, Meng; Bandara, K B Anura T; Kobayashi, Seiki; Cheng, Xunjia; Hirayama, Kenji; Rajapakse, R P V Jayanthe

    2016-03-01

    We have proposed the revival of the name Entamoeba nuttalli for a virulent ameba strain, P19-061405, from a rhesus macaque and located it phylogenetically between E. histolytica and E. dispar. As E. nuttalli was originally described for an ameba found in a toque macaque in Sri Lanka, the prevalence and characteristics of Entamoeba species in wild toque macaques were examined. PCR analysis of 227 stool samples from six locations showed positive rates for E. nuttalli, E. dispar, and E. histolytica of 18.5%, 0.4%, and 0%, respectively. Fifteen E. nuttalli strains were cultured successfully from five locations. The 18S ribosomal RNA gene showed only three nucleotide differences in comparison with P19-061405 strain. In isoenzyme analysis, the pattern of hexokinase in Sri Lankan strains was different from that of P19-061405 strains and the difference was confirmed by analysis of the genes. Hepatic inoculation of one of the Sri Lankan E. nuttalli strains in hamsters resulted in amebic abscess formation and body weight loss. These results demonstrate that E. nuttalli is prevalent in wild toque macaques and that several characteristics of the strains are unique. We conclude that use of the name E. nuttalli is appropriate for the new Entamoeba species found in nonhuman primates. PMID:26333681

  2. Reconstruction of health service systems in the post-conflict Northern Province in Sri Lanka.

    PubMed

    Nagai, Mari; Abraham, Sandirasegaram; Okamoto, Miyoko; Kita, Etsuko; Aoyama, Atsuko

    2007-09-01

    Public health problems in armed conflicts have been well documented, however, effective national health policies and international assistance strategies in transition periods from conflict to peace have not been well established. After the long lasted conflicts in Sri Lanka, the Government and the rebel LTTE signed a cease-fire agreement in February 2002. As the peace negotiation has been disrupted since April 2003, a long-term prospect for peace is yet uncertain at present. The objective of this research is to detect unmet needs in health services in Northern Province in Sri Lanka, and to recommend fair and effective health strategies for post-conflict reconstruction. First, we compared a 20-year trend of health services and health status between the post-conflict Northern Province and other areas not directly affected by conflict in Sri Lanka by analyzing data published by Sri Lankan government and other agencies. Then, we conducted open-ended self-administered questionnaires to health care providers and inhabitants in Northern Province, and key informant interviews in Northern Province and other areas. The major health problems in Northern Province were high maternal mortality, significant shortage of human resources for health (HRH), and inadequate water and sanitation systems. Poor access to health facilities, lack of basic health knowledge, insufficient health awareness programs for inhabitants, and mental health problems among communities were pointed by the questionnaire respondents. Shortage of HRH and people's negligence for health were perceived as the major obstacles to improving the current health situation in Northern Province. The key informant interviews revealed that Sri Lankan HRH outside Northern Province had only limited information about the health issues in Northern Province. It is required to develop and allocate HRH strategically for the effective reconstruction of health service systems in Northern Province. The empowerment of inhabitants

  3. Dissecting the genetic structure and admixture of four geographical Malay populations.

    PubMed

    Deng, Lian; Hoh, Boon-Peng; Lu, Dongsheng; Saw, Woei-Yuh; Twee-Hee Ong, Rick; Kasturiratne, Anuradhani; de Silva, H Janaka; Zilfalil, Bin Alwi; Kato, Norihiro; Wickremasinghe, Ananda R; Teo, Yik-Ying; Xu, Shuhua

    2015-01-01

    The Malay people are an important ethnic composition in Southeast Asia, but their genetic make-up and population structure remain poorly studied. Here we conducted a genome-wide study of four geographical Malay populations: Peninsular Malaysian Malay (PMM), Singaporean Malay (SGM), Indonesian Malay (IDM) and Sri Lankan Malay (SLM). All the four Malay populations showed substantial admixture with multiple ancestries. We identified four major ancestral components in Malay populations: Austronesian (17%-62%), Proto-Malay (15%-31%), East Asian (4%-16%) and South Asian (3%-34%). Approximately 34% of the genetic makeup of SLM is of South Asian ancestry, resulting in its distinct genetic pattern compared with the other three Malay populations. Besides, substantial differentiation was observed between the Malay populations from the north and the south, and between those from the west and the east. In summary, this study revealed that the genetic identity of the Malays comprises a mixed entity of multiple ancestries represented by Austronesian, Proto-Malay, East Asian and South Asian, with most of the admixture events estimated to have occurred 175 to 1,500 years ago, which in turn suggests that geographical isolation and independent admixture have significantly shaped the genetic architectures and the diversity of the Malay populations. PMID:26395220

  4. Dissecting the genetic structure and admixture of four geographical Malay populations

    PubMed Central

    Deng, Lian; Hoh, Boon-Peng; Lu, Dongsheng; Saw, Woei-Yuh; Twee-Hee Ong, Rick; Kasturiratne, Anuradhani; Janaka de Silva, H.; Zilfalil, Bin Alwi; Kato, Norihiro; Wickremasinghe, Ananda R.; Teo, Yik-Ying; Xu, Shuhua

    2015-01-01

    The Malay people are an important ethnic composition in Southeast Asia, but their genetic make-up and population structure remain poorly studied. Here we conducted a genome-wide study of four geographical Malay populations: Peninsular Malaysian Malay (PMM), Singaporean Malay (SGM), Indonesian Malay (IDM) and Sri Lankan Malay (SLM). All the four Malay populations showed substantial admixture with multiple ancestries. We identified four major ancestral components in Malay populations: Austronesian (17%–62%), Proto-Malay (15%–31%), East Asian (4%–16%) and South Asian (3%–34%). Approximately 34% of the genetic makeup of SLM is of South Asian ancestry, resulting in its distinct genetic pattern compared with the other three Malay populations. Besides, substantial differentiation was observed between the Malay populations from the north and the south, and between those from the west and the east. In summary, this study revealed that the genetic identity of the Malays comprises a mixed entity of multiple ancestries represented by Austronesian, Proto-Malay, East Asian and South Asian, with most of the admixture events estimated to have occurred 175 to 1,500 years ago, which in turn suggests that geographical isolation and independent admixture have significantly shaped the genetic architectures and the diversity of the Malay populations. PMID:26395220

  5. Equity in Education: Opportunities and Challenges In A Changing Sri Lanka

    ERIC Educational Resources Information Center

    Sedere, Upali M.

    2010-01-01

    Equity is a major concern for all development actors. Although Sri Lanka has successfully addressed equity issues in education sector there are unresolved factors and variables those perpetuate inequity. There are emerging new equity issues those that Sri Lanka needs to address. The changing population dynamics and the huge middle class population…

  6. Rostral horn evolution among agamid lizards of the genus ceratophora endemic to Sri Lanka

    SciTech Connect

    Schulte II, James A.; Macey, J. Robert; Pethiyagoda, Rohan; Larson, Allan

    2001-07-10

    The first phylogenetic hypothesis for the Sri Lankan agamid lizard genus Ceratophora is presented based on 1670 aligned base positions (472 parsimony informative) of mitochondrial DNA sequences, representing coding regions for eight tRNAs, ND2, and portions of ND1 and COI. Phylogenetic analysis reveals multiple origins and possibly losses of rostral horns in the evolutionary history of Ceratophora. Our data suggest a middle Miocene origin of Ceratophora with the most recent branching of recognized species occurring at the Pliocene/Pleistocene boundary. Haplotype divergence suggests that an outgroup species, Lyriocephalus scutatus, dates at least to the Pliocene. These phylogenetic results provide a framework for comparative studies of the behavioral ecological importance of horn evolution in this group.

  7. Reactogenicity and safety of the human rotavirus vaccine, Rotarix™ in The Philippines, Sri Lanka, and India: A post-marketing surveillance study

    PubMed Central

    Bravo, Lulu; Chitraka, Amarjeet; Liu, Aixue; Choudhury, Jaydeep; Kumar, Kishore; Berezo, Lennie; Cimafranca, Leonard; Chatterjee, Pallab; Garg, Pankaj; Siriwardene, Prasanna; Bernardo, Rommel; Mehta, Shailesh; Balasubramanian, Sundaram; Karkada, Naveen; Htay Han, Htay

    2014-01-01

    Regulatory bodies in The Philippines, Sri Lanka, and India require post-marketing surveillance to provide additional safety data on Rotarix™ in real-life settings. In such studies conducted in The Philippines (November 2006 to July 2012; NCT00353366), Sri Lanka (November 2008 to August 2009; NCT00779779), and India (August 2009 to April 2010; NCT00938327), 2 doses of Rotarix™ were administered according to the local prescribing information (PI). The occurrence of at least Grade “2”/”3” solicited adverse event (AE) (fever, vomiting, or diarrhea), within 15 days in The Philippines or 8 days in Sri Lanka and India; unsolicited AEs within 31 days and serious adverse events (SAEs) throughout the study were recorded. Of the 1494, 522, and 332 infants enrolled in The Philippines, Sri Lanka, and India, 14.7% 14.9% and 12.7% infants, respectively recorded at least Grade “2”/”3” solicited AEs. The most commonly reported solicited AEs were irritability in The Philippines (32.2% post-Dose-1; 23.5% post-Dose-2) and India (23.0% post-Dose-1; 13.2% post-Dose-2), and fever (18.0% post-Dose-1; 20.2% post-Dose-2) in Sri Lanka. Unsolicited AEs were recorded in 24.5% (The Philippines), 4.8% (Sri Lanka), and 6.9% (India) of infants. Forty-one SAEs were recorded in the Philippines of which 6 (decreased oral intake with increased sleeping time and constipation; pneumonia, urinary tract infection, and intussusception) were considered by the investigators as causally related to vaccination. One vaccine-unrelated SAE occurred in a Sri Lankan infant. All SAEs resolved and the infants recovered. Two doses of Rotarix™, administered to healthy infants according to local PI, were well tolerated in The Philippines, Sri Lanka, and India. PMID:25424932

  8. Population Education Country Programmes.

    ERIC Educational Resources Information Center

    Population Education in Asia and the Pacific Newsletter, 1985

    1985-01-01

    Discusses population education programs in China, India, Indonesia, Maldives, Nepal, Pakistan, Philippines, Sri Lanka, and Vietnam. Sri Lanka is developing audio-visual materials and integrating population education into secondary science and social studies curricula. Nepal is transmitting nonformal population education messages to adults through…

  9. An assessment of CSIRO Conformal Cubic Atmospheric Model simulations over Sri Lanka

    NASA Astrophysics Data System (ADS)

    Thevakaran, A.; McGregor, J. L.; Katzfey, J.; Hoffmann, P.; Suppiah, R.; Sonnadara, D. U. J.

    2016-03-01

    In this study, we present an assessment of the Conformal Cubic Atmospheric Model (CCAM) 50 km simulations forced by the sea surface temperature and sea ice concentration of six global climate models (GCMs) (ACCESS1-0, CCSM4, GFDL-CM3, NorESM, MPI-ESM and CNRM-CM5) from the Coupled Model Inter-comparison Project Phase 5 (CMIP5) over South Asia, centred on Sri Lanka. The model simulations were compared with the data provided by the Asian Precipitation Highly Resolved Observational Data Integration towards Evaluation of Water Resource (APHRODITE) project and ERA-Interim from the European Centre for Medium range Weather Forecast (ECMWF) over a broad region centred on Sri Lanka. This broad region includes South Asia and northern Indian Ocean. Statistical measures such as pattern correlations, mean biases and root mean square errors were calculated separately for the four seasons. Results based on statistical tests indicate that the current CCAM simulations capture the spatial patterns of 10 m wind speed, mean sea level pressure, temperature and rainfall over a broad region over South Asia fairly well. The annual cycles of temperature and rainfall were also compared against observations over the northern and southern regions of Sri Lanka by taking the field average of each model and the observed data. The characteristics of the observed annual variations of rainfall and temperature over the smaller domains are not very well captured by the CCAM simulations. There are differences in the magnitudes of the temperature and rainfall in the six member CCAM simulations. Comparatively, the two CCAM simulations CNRM-CM5 and GFDL-CM3 show slightly better agreement over the Sri Lankan region.

  10. The process and costs of publishing medical journals in Sri Lanka: an economic evaluation

    PubMed Central

    Perera, Y S; Abeygunasekara, A M

    2011-01-01

    Objectives Medical journals have contributed to the advancement of medicine by helping to disseminate scientific knowledge and providing a forum for medical communities to debate issues in depth. To the authors' knowledge, there are no studies examining the process of medical journal publication in developing Asian countries. The authors analysed the process and costs of publishing medical journals in Sri Lanka, a developing country in South Asia. Methods Data were collected by interviewing the editors and perusing the records at the editorial offices of the respective medical journals. Articles published in 2009 (or 2008 for journals not published in 2009) were analysed by perusing the respective journals. Results A total of 44 medical journals were published in Sri Lanka's history, of which only 28 journals remained in publication after 2007. A majority (54%) of the journals published after 2007 were published once per year. Seventeen journals in publication after 2007 were published in paper version only, and 11 journals were also available online. The mean cost of printing one issue was Sri Lankan Rupees (LKR) 97 720 (US$888) (range LKR 28 000–270 000). The cost of distribution ranged from LKR 2000 to 140 000 (US$18–1273). The mean cost of publishing one article was LKR 6646 (US$60). A total of 456 articles were published in 2009 (/2008). The total number of pages published was 1723. Conclusion The infrastructure for medical journal publishing in Sri Lanka has many good qualities such as free access, minimum charges for authors and potential for online availability. The journals are solely academic (non-profit), but the costs remain high. PMID:22021741

  11. An investigation into the role of alcohol in self-harm in rural Sri Lanka: a protocol for a multimethod, qualitative study

    PubMed Central

    Sørensen, Jane Brandt; Rheinländer, Thilde; Sørensen, Birgitte Refslund; Pearson, Melissa; Agampodi, Thilini; Siribaddana, Sisira; Konradsen, Flemming

    2014-01-01

    Introduction Sri Lanka has one of the highest suicide and self-harm rates in the world and although alcohol has been found to be a risk factor for self-harm in Sri Lanka, we know little about the connection between the two. This paper comprises a protocol for a qualitative study investigating alcohol's role in self-harm in rural Sri Lanka at three levels: the individual, community and policy level. The analysis will bring new understanding of the link between alcohol and self-harm in Sri Lanka, drawing on structural, cultural and social concepts. It will equip researchers, health systems and policy makers with vital information for developing strategies to address alcohol-related problems as they relate to self-harm. Methods and analysis To capture the complexity of the link between alcohol and self-harm in the Anuradhapura district in the North Central Province in Sri Lanka, qualitative methods will be utilised. Specifically, the data will consist of serial narrative life-story interviews with up to 20 individuals who have non-fatally self-harmed and where alcohol directly or indirectly was involved in the incidence as well as with their significant others; observations in communities and families; six focus group discussions with community members; and key-informant interviews with 15–25 stakeholders who have a stake in alcohol distribution, marketing, policies, prevention and treatment as they relate to self-harm. Ethics and dissemination The study has received ethical approval from the Ethical Review Committee of the Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka. A sensitive data collection technique will be used and ethical issues will be considered throughout the study. Results The results will be disseminated in scientific peer-reviewed articles in collaboration with Sri Lankan and other international research partners. PMID:25293385

  12. Indoor Fine Particle (PM2.5) Pollution Exposure due to Secondhand Smoke in Selected Public Places of Sri Lanka

    PubMed Central

    Nandasena, Sumal; Wickremasinghe, Ananda Rajitha; Lee, Kiyoung; Sathiakumar, Nalini

    2012-01-01

    Background Secondhand smoke accounts for a considerable proportion of deaths due to tobacco smoke. Although the existing laws ban indoor smoking in public places in Sri Lanka, the level of compliance is unknown. Methods Fine particulate matter (PM2.5) levels in 20 public places in Colombo, Sri Lanka were measured by a PM monitor (Model AM510 - SIDEPAK Personal Aerosol Monitor). Different types of businesses (restaurants, bars, cafés and entertainment venues) were selected by purposive sampling. Only the places where smoking was permitted were considered. Results The average indoor PM2.5 ranged from 33 to 299 μg/m3. The average outdoor PM2.5 ranged from 18 to 83 μg/m3. The indoor to outdoor PM2.5 ratio ranged from 1.05 to 14.93. In all venues, indoor PM2.5 levels were higher than the Sri Lankan ambient PM2.5 standard of 50 μg/m3. All indoor locations had higher PM2.5 levels as compared to their immediate outdoor surroundings. Conclusion The study highlights the importance of improving ventilation and enforcing laws to stop smoking in public places. PMID:22473526

  13. U-Pb isotopic systematics of zircons from prograde and retrograde transition zones in high-grade orthogneisses, Sri Lanka

    SciTech Connect

    Baur, N.; Liew, T.C.; Todt, W.; Hofmann, A.W. ); Kroener, A. ); Williams, I.S. )

    1991-07-01

    The authors present U-Pb zircon isotopic data from locally restricted prograde (arrested in situ charnockitization) and retrograde metamorphic transition zones, which are well exposed in Proterozoic orthogneisses tectonically interbanded with granulite facies supracrustal rocks of the Highland Group in Sri Lanka. These granitoid rocks yield apparent ages of 1942 {plus minus} 22 Ma, {approximately} 770 Ma, {approximately} 660 Ma, and {approximately} 560 Ma. All samples show severe Pb-loss some 550-560 Ma ago. The main phase of granulite-formation could not be dated unambiguously but is bracketed between {approximately} 660 Ma and {approximately} 550 Ma. The pervasive Pb-loss event around 550-560 Ma reflects the end of this period of high-grade metamorphism and was associated with widespread igneous activity and retrogression. This is constrained by the 550 {plus minus} 3 Ma intrusion age for a post-tectonic granite. They relate this late phase of thermal activity to crustal uplift of the Sri Lankan granulites. This data unambiguously prove the high-grade history of the Sri Lanka gneisses to be a late Precambrian event that may be related to the Pan-African evolution along the eastern part of Africa.

  14. Sri Lanka, Colored Height

    NASA Technical Reports Server (NTRS)

    2005-01-01

    The topography of the island nation of Sri Lanka is well shown in this color-coded shaded relief map generated with digital elevation data from the Shuttle Radar Topography Mission (SRTM).

    Two visualization methods were combined to produce the image: shading and color coding of topographic height. The shade image was derived by computing topographic slope in the northwest-southeast direction, so that northwest slopes appear bright and southeast slopes appear dark. Color coding is directly related to topographic height, with green at the lower elevations, rising through yellow and tan, to white at the highest elevations.

    For this special view heights below 10 meters (33 feet) above sea level have been colored red. These low coastal elevations extend 5 to 10 km (3.1 to 6.2 mi) inland on Sri Lanka and are especially vulnerable to flooding associated with storm surges, rising sea level, or, as in the aftermath of the earthquake of December 26, 2004, tsunami. These so-called tidal waves have occurred numerous times in history and can be especially destructive, but with the advent of the near-global SRTM elevation data planners can better predict which areas are in the most danger and help develop mitigation plans in the event of particular flood events.

    Sri Lanka is shaped like a giant teardrop falling from the southern tip of the vast Indian subcontinent. It is separated from India by the 50km (31mi) wide Palk Strait, although there is a series of stepping-stone coral islets known as Adam's Bridge that almost form a land bridge between the two countries. The island is just 350km (217mi) long and only 180km (112mi) wide at its broadest, and is about the same size as Ireland, West Virginia or Tasmania.

    The southern half of the island is dominated by beautiful and rugged hill country, and includes Mt Pidurutalagala, the islandaE(TM)s highest point at 2524 meters (8281 ft). The entire northern half comprises a large plain extending from the edge of

  15. The gift of disaster: the commodification of good intentions in post-tsunami Sri Lanka.

    PubMed

    Korf, Benedikt; Habullah, Shahul; Hollenbach, Pia; Klem, Bart

    2010-01-01

    This paper analyses the commodification of post-tsunami aid in Sri Lanka, a process that 'contaminated' the 'purity' of good intentions with the politics of patronage and international aid. It argues that gifts are not just material transfers of 'aid', but also embodiments of cultural symbolism, social power, and political affiliations. The tsunami gift re-enforced and reconfigured exchange relationships among different patrons and clients in Sri Lankan communities, perpetuating the political economy that has driven social conflict and discontent in the post-independence years. Beyond dominant rationales of ethnic or political party patronage, the paper finds that gifts by disingenuous patrons not only became patrimonial, but that the patrimonial rationale emerged as much from above as from below--a dynamic that became nearly inescapable and self-reinforcing. Through three case studies, we explore the intricate chain of relations, obligations, and expectations pertinent in the co-evolving, but often contradictory, gift rationales that permeate the practices, performances, and discourses of tsunami aid. PMID:19486354

  16. The Impact of School Quality, Socioeconomic Factors, and Child Health on Students' Academic Performance: Evidence from Sri Lankan Primary Schools

    ERIC Educational Resources Information Center

    Aturupane, Harsha; Glewwe, Paul; Wisniewski, Suzanne

    2013-01-01

    One of the eight Millennium Development Goals is that all children in developing countries should complete primary education. Much progress has been made toward this goal, but completing primary school does not ensure that students attain basic literacy and numeracy skills. Indeed, there is ample evidence that many children in developing countries…

  17. Trauma-Related Impairment in Children--A Survey in Sri Lankan Provinces Affected by Armed Conflict

    ERIC Educational Resources Information Center

    Elbert, Thomas; Schauer, Maggie; Schauer, Elisabeth; Huschka, Bianca; Hirth, Michael; Neuner, Frank

    2009-01-01

    Objectives: The present study examined traumatic experiences, PTSD, and co-morbid symptoms in relation to neuropsychological and school performance in school children affected by two decades of civil war and unrest. Method: The epidemiological survey of children's mental health included a representative sample of 420 school children. Local…

  18. An epidemiological study of the health of Sri Lankan tea plantation workers associated with long term exposure to paraquat.

    PubMed

    Senanayake, N; Gurunathan, G; Hart, T B; Amerasinghe, P; Babapulle, M; Ellapola, S B; Udupihille, M; Basanayake, V

    1993-03-01

    Pulmonary function tests (FVC, FEV1, FEV1/FVC%, TLCO, single breath CO diffusion), chest x ray film, renal function (serum creatinine and blood urea nitrogen), liver function (serum alanine aminotransferase, aspartate transferase, and alkaline phosphatase, bilirubin, total protein, and albumin), a haematological screen (haemoglobin and packed cell volume), and a general clinical examination were performed on 85 paraquat spraymen (mean spraying time 12 years) and on two control groups (76 factory workers and 79 general workers) frequency matched for age and years of occupational service. All the subjects were men. There were no clinically important differences in any of the measurements made between the study group and the two control groups. In particular the results of the lung function tests, appropriate for paraquat toxicity of the study group, were similar to those of the control groups. The same was true of blood tests for liver and kidney function. The incidence of skin damage, nose bleeds, and nail damage in the study group was slightly higher than in the control groups but lower than the incidence reported for paraquat workers in previous studies. The results of this study confirmed that long term spraying of paraquat, at the concentrations used, produced no adverse health effects, in particular no lung damage, attributable to the occupational use of the herbicide. PMID:8457493

  19. Posttraumatic Stress Disorder among Sri Lankan University Students as a Consequence of Their Exposure to Family Violence

    ERIC Educational Resources Information Center

    Haj-Yahia, Muhammad M.; Tishby, Orya; de Zoysa, Piyanjali

    2009-01-01

    The article presents the results of a study on the association between exposure to family violence (i.e., witnessing interparental violence and experiencing parental violence) during childhood and adolescence and adult posttraumatic stress disorder (PTSD). The study was conducted among a self-selected convenience sample of 476 students from Sri…

  20. Regional differences of leptospirosis in Sri Lanka: observations from a flood-associated outbreak in 2011.

    PubMed

    Agampodi, Suneth B; Dahanayaka, Niroshan J; Bandaranayaka, Anoma K; Perera, Manoj; Priyankara, Sumudu; Weerawansa, Prasanna; Matthias, Michael A; Vinetz, Joseph M

    2014-01-01

    Leptospirosis is known to be an important cause of weather disaster-related infectious disease epidemics. In 2011, an outbreak of leptospirosis occurred in the relatively dry district of Anuradhapura, Sri Lanka where diagnosis was resisted by local practitioners because leptospirosis was not known in the area and the clinical presentation was considered atypical. To identify the causative Leptospira associated with this outbreak, we carried out a cross-sectional study. Consecutive clinically suspected cases in this district were studied during a two-and-a-half-month period. Of 96 clinically suspected cases, 32 (33.3%) were confirmed by qPCR, of which the etiological cause in 26 cases was identified using 16S rDNA sequencing to the species level. Median bacterial load was 4.1 × 10(2)/mL (inter-quartile range 3.1-6.1 × 10(2)/mL). In contrast to a 2008 Sri Lankan leptospirosis outbreak in the districts of Kegalle, Kandy, and Matale, in which a predominance of Leptospira interrogans serovars Lai and Geyaweera was found, most cases in the 2011 outbreak were caused by Leptospira kirschneri. Seven (21.9%) confirmed cases had acute renal failure; five (15.6%) had myocarditis; severe thrombocytopenia (<20,000/uL) was seen in five (15.6%) cases. This outbreak of leptospirosis in the relatively dry zone of Sri Lanka due primarily to L. kirschneri was characterized by markedly different clinical presentations and low leptospiremia. These observations and data demonstrate the public health relevance of molecular diagnostics in such settings, possibly related to the microgeographic variations of different Leptospira species, but of particular value to public health intervention in what appears to have been a regionally neglected tropical disease. PMID:24454971

  1. Destination: Sri Lanka. Video Guide.

    ERIC Educational Resources Information Center

    Legowski, Margaret

    This video guide was developed by the Peace Corps' Office of World Wise Schools. The activities it describes are designed to supplement elementary and secondary students' exploration of South Asia and to enhance their correspondence with a Peace Corps volunteer. Used in conjunction with the videotape "Destination: Sri Lanka," the activities in the…

  2. Changing gender roles and health impacts among female workers in export-processing industries in Sri Lanka.

    PubMed

    Attanapola, Chamila T

    2004-06-01

    Since the economic liberalization in 1977, a large number of Sri Lankan women have entered the labour market and engaged in income-generating activities. Some women choose to travel abroad as domestic workers, while others choose to work in export-processing industries. This process has a profound impact on gender and gender roles in Sri Lanka. Young rural women have changed their traditional women's roles to become independent daughters, efficient factory workers and partially modernized women. Even though changing gender roles are identified as a positive impact of industrial work, the new social, cultural, and legal environments of industrial work have negative impacts on these women's lives. This paper explores health impacts of changing gender roles and practices of young rural women, focusing on the experiences of female workers in export-processing industries. Further, it contributes to the literature on gender and health, and on qualitative approaches within health geographic studies. A model is formulated to suggest a conceptual framework for studying women's health. The model describes the determinant factors of individual health status based on the question of who (personal attributes) does what (type of work) where (place), when and how (behaviours). These are also determinant factors of gender and gender roles of a society. The three types of health problems (reproductive, productive and mental health) of a woman, in this case a female industrial worker, are determined by her gender roles and practices associated with these roles. PMID:15047086

  3. Test burn with PCB-oil in a local cement kiln in Sri Lanka.

    PubMed

    Karstensen, Kåre Helge; Mubarak, Azeez M; Gunadasa, H N; Wijagunasekara, Bandulasoma; Ratnayake, Niranjanie; Alwis, Ajith De; Fernando, Jayavilal

    2010-02-01

    The production and use of polychlorinated biphenyls (PCBs) have ceased and most developed countries have disposed off their stocks long time ago. PCBs can however still be found in the environment and one important source is accumulated stocks in developing countries. Sound treatment of PCB is costly and most developing countries do not have dedicated hazardous waste incinerators or non-combustion technologies available for domestic disposal and can usually not afford export. High temperature cement kilns have been used to treat organic hazardous wastes in developed countries for decades and shown to constitute a sound option if well managed and controlled. In contrast to dedicated hazardous waste incinerators and other treatment techniques, cement kilns are already in place in virtually every country and may constitute a treatment option. The objective of this study was therefore to carry out the first test burn with PCB-oil in a developing country cement kiln and to assess its feasibility and destruction performance. The 3 d test burn demonstrated that the Sri Lankan cement kiln was able to destroy PCB in an irreversible and environmental sound manner without causing any new formation of PCDD/PCDF or HCB. The destruction and removal efficiency (DRE) was better than 99.9999% at the highest PCB feeding rate. PMID:20004933

  4. A Comprehensive Assessment of Lymphatic Filariasis in Sri Lanka Six Years after Cessation of Mass Drug Administration

    PubMed Central

    Rao, Ramakrishna U.; Nagodavithana, Kumara C.; Samarasekera, Sandhya D.; Wijegunawardana, Asha D.; Premakumara, Welmillage D. Y.; Perera, Samudrika N.; Settinayake, Sunil; Miller, J. Phillip; Weil, Gary J.

    2014-01-01

    Background The Sri Lankan Anti-Filariasis Campaign conducted 5 rounds of mass drug administration (MDA) with diethycarbamazine plus albendazole between 2002 and 2006. We now report results of a comprehensive surveillance program that assessed the lymphatic filariasis (LF) situation in Sri Lanka 6 years after cessation of MDA. Methodology and Principal Findings Transmission assessment surveys (TAS) were performed per WHO guidelines in primary school children in 11 evaluation units (EUs) in all 8 formerly endemic districts. All EUs easily satisfied WHO criteria for stopping MDA. Comprehensive surveillance was performed in 19 Public Health Inspector (PHI) areas (subdistrict health administrative units). The surveillance package included cross-sectional community surveys for microfilaremia (Mf) and circulating filarial antigenemia (CFA), school surveys for CFA and anti-filarial antibodies, and collection of Culex mosquitoes with gravid traps for detection of filarial DNA (molecular xenomonitoring, MX). Provisional target rates for interruption of LF transmission were community CFA <2%, antibody in school children <2%, and filarial DNA in mosquitoes <0.25%. Community Mf and CFA prevalence rates ranged from 0–0.9% and 0–3.4%, respectively. Infection rates were significantly higher in males and lower in people who denied prior treatment. Antibody rates in school children exceeded 2% in 10 study sites; the area that had the highest community and school CFA rates also had the highest school antibody rate (6.9%). Filarial DNA rates in mosquitoes exceeded 0.25% in 10 PHI areas. Conclusions Comprehensive surveillance is feasible for some national filariasis elimination programs. Low-level persistence of LF was present in all study sites; several sites failed to meet provisional endpoint criteria for LF elimination, and follow-up testing will be needed in these areas. TAS was not sensitive for detecting low-level persistence of filariasis in Sri Lanka. We recommend use of

  5. Sri Lanka drops leading condom.

    PubMed

    1984-01-01

    Sri Lanka's Family Planning Association has stopped selling its Preethi Regular condom, the backbone of its social marketing program for nearly a decade. Last year nearly 7 times as many Preethi condoms were sold as all other brands combined. The decision was reported to be caused by budget constraints following the International Planned Parenthood Federation's (IPPF) new policy of limiting the number of Preethi Regular condoms supplied to Sri Lanka. IPPF's Asian Regional Officer reported that the Preethi condom is a costly product, and that as many as needed of a US Agency for International Development (USAID) supplied product will be sent to Sri Lanka. The Contraceptive Retail Sales (CRS) program has devised a new sales strategy, based partly on the introduction of a high-priced condom to fill the gap left by the discontinuation of the Preethi Regular. The new Preethi Gold condom is expected to help the project become more financially self-reliant while taing advantage of Preethi's marketplace popularity. Preethi Gold is manufactured by the Malaysia Rubber Company and costs the project US $4.85/gross. It is sold for US $.14 for 3, about 3 times the price of a Preethi Regular. The project is also pushing the Panther condom, donated to IPPF by USAID. 2 Panther condoms sell for about 3.6U, about the cost of Preethi Regulars. The project also sells Moonbeam, Rough Rider, and Stimula condoms, the latter 2 at full commercial prices. A smooth transfer of demand from Preethi to Panther had been desired, but by the end of 1983 some retailers were hesitating to make the product switch because some Preethi Regulars were still available. Total condom sales in 1983 were down by nearly 590,000 from the approximately 6,860,000 sold in 1982. Total condom sales for the 1st quarter of 1984 were slightly over 1,218,000 pieces, compared to about 1,547,000 for the same quarter in 1983, a decline of 21%. The Family Planning Association is gearing up to reverse the downward trend

  6. Regression analysis of "current status" life tables on duration of breastfeeding in Sri Lanka.

    PubMed

    Smith, D P

    1985-01-01

    strongly as lifetime urban residence relative to women who are rural and uneducated. Being at parity 5 or above or working at home almost as sharply increases durations. The use of contraception has slightly smaller positive effects. The patterns suggest that as Sri Lankan women become increasingly well educated and urban, and as family sizes decline, durations of breastfeeding will decline. Equally important however, even among better educated urban wives, breastfeeding continues longer than is typical of western countries. PMID:4081811

  7. USE OF AND ATTITUDES TOWARD TOBACCO AND ALCOHOL AMONG ADULTS IN SOUTHERN SRI LANKA

    PubMed Central

    Lombardo, Sarah; Perera, Bilesha; Beaudry, Lauren; Grad, Jennifer; Maselko, Joanna; Østbye, Truls

    2014-01-01

    The adverse health effects of tobacco and alcohol are well known. Alcohol consumption is increasing in Sri Lanka, but few population studies have been conducted. The objective of this study was to document tobacco and alcohol consumption levels among adults in southern Sri Lanka and to identify the main reasons for using or refraining from alcohol and tobacco products. Tobacco and alcohol use within Sri Lanka is relatively common, particularly among adult males. Reasons given for smoking and drinking frequently relate to social and image-based motivators. Women may be especially susceptible to the influence of peer pressure in social situations. Public health efforts should consider the use of demographic-specific anti-tobacco and anti-alcohol messages, as the motivators driving behavior appear to differ across gender and age groups. PMID:24437324

  8. Use of and attitudes toward tobacco and alcohol among adults in southern Sri Lanka.

    PubMed

    Lombardo, Sarah; Perera, Bilesha; Beaudry, Lauren; Grad, Jennifer; Maselko, Joanna; Ostbye, Truls

    2013-09-01

    The adverse health effects of tobacco and alcohol are well known. Alcohol consumption is increasing in Sri Lanka, but few population studies have been conducted. The objective of this study was to document tobacco and alcohol consumption levels among adults in southern Sri Lanka and to identify the main reasons for using or refraining from alcohol and tobacco products. Tobacco and alcohol use within Sri Lanka is relatively common, particularly among adult males. Reasons given for smoking and drinking frequently relate to social and image-based motivators. Women may be especially susceptible to the influence of peer pressure in social situations. Public health efforts should consider the use of demographic-specific anti-tobacco and anti-alcohol messages, as the motivators driving behavior appear to differ across gender and age groups. PMID:24437324

  9. Polymerase chain reaction detection of Leishmania DNA in skin biopsy samples in Sri Lanka where the causative agent of cutaneous leishmaniasis is Leishmania donovani.

    PubMed

    Ranasinghe, Shalindra; Wickremasinghe, Renu; Hulangamuwa, Sanjeeva; Sirimanna, Ganga; Opathella, Nandimithra; Maingon, Rhaiza D C; Chandrasekharan, Vishvanath

    2015-12-01

    Leishmania donovani is the known causative agent of both cutaneous (CL) and visceral leishmaniasis in Sri Lanka. CL is considered to be under-reported partly due to relatively poor sensitivity and specificity of microscopic diagnosis. We compared robustness of three previously described polymerase chain reaction (PCR) based methods to detect Leishmania DNA in 38 punch biopsy samples from patients presented with suspected lesions in 2010. Both, Leishmania genus-specific JW11/JW12 KDNA and LITSR/L5.8S internal transcribed spacer (ITS)1 PCR assays detected 92% (35/38) of the samples whereas a KDNA assay specific forL. donovani (LdF/LdR) detected only 71% (27/38) of samples. All positive samples showed a L. donovani banding pattern upon HaeIII ITS1 PCR-restriction fragment length polymorphism analysis. PCR assay specificity was evaluated in samples containing Mycobacterium tuberculosis, Mycobacterium leprae, and human DNA, and there was no cross-amplification in JW11/JW12 and LITSR/L5.8S PCR assays. The LdF/LdR PCR assay did not amplify M. leprae or human DNA although 500 bp and 700 bp bands were observed in M. tuberculosis samples. In conclusion, it was successfully shown in this study that it is possible to diagnose Sri Lankan CL with high accuracy, to genus and species identification, using Leishmania DNA PCR assays. PMID:26676321

  10. A phylogeny of the only ground-dwelling radiation of Cyrtodactylus (Squamata, Gekkonidae): diversification of Geckoella across peninsular India and Sri Lanka.

    PubMed

    Agarwal, Ishan; Karanth, K Praveen

    2015-01-01

    The subgenus Geckoella, the only ground-dwelling radiation within Cyrtodactylus, closely overlaps in distribution with brookii group Hemidactylus in peninsular India and Sri Lanka. Both groups have Oligocene origins, the latter with over thrice as many described species. The striking difference in species richness led us to believe that Geckoella diversity is underestimated, and we sampled for Geckoella across peninsular India. A multi-locus phylogeny reveals Geckoella diversity is hugely underestimated, with at least seven undescribed species, doubling previously known richness. Strikingly, the new species correspond to cryptic lineages within described Indian species (complexes); a number of these endemic lineages from the hills of peninsular India outside the Western Ghats, highlighting the undocumented diversity of the Indian dry zone. The Geckoella phylogeny demonstrates deep splits between the Indian species and Sri Lankan G. triedrus, and between Indian dry and wet zone clades, dating back to the late Oligocene. Geckoella and brookii group Hemidactylus show contrasting diversification patterns. Geckoella shows signals of niche conservatism and appears to have retained its ancestral forest habitat. The late Miocene burst in speciation in Geckoella may be linked to the expansion of rain forests during the mid-Miocene climatic optimum and subsequent fragmentation with increasing late Miocene aridification. PMID:25281922

  11. Polymerase chain reaction detection of Leishmania DNA in skin biopsy samples in Sri Lanka where the causative agent of cutaneous leishmaniasis is Leishmania donovani

    PubMed Central

    Ranasinghe, Shalindra; Wickremasinghe, Renu; Hulangamuwa, Sanjeeva; Sirimanna, Ganga; Opathella, Nandimithra; Maingon, Rhaiza DC; Chandrasekharan, Vishvanath

    2015-01-01

    Leishmania donovani is the known causative agent of both cutaneous (CL) and visceral leishmaniasis in Sri Lanka. CL is considered to be under-reported partly due to relatively poor sensitivity and specificity of microscopic diagnosis. We compared robustness of three previously described polymerase chain reaction (PCR) based methods to detectLeishmania DNA in 38 punch biopsy samples from patients presented with suspected lesions in 2010. Both, Leishmaniagenus-specific JW11/JW12 KDNA and LITSR/L5.8S internal transcribed spacer (ITS)1 PCR assays detected 92% (35/38) of the samples whereas a KDNA assay specific forL. donovani (LdF/LdR) detected only 71% (27/38) of samples. All positive samples showed a L. donovani banding pattern upon HaeIII ITS1 PCR-restriction fragment length polymorphism analysis. PCR assay specificity was evaluated in samples containing Mycobacterium tuberculosis, Mycobacterium leprae, and human DNA, and there was no cross-amplification in JW11/JW12 and LITSR/L5.8S PCR assays. The LdF/LdR PCR assay did not amplify M. leprae or human DNA although 500 bp and 700 bp bands were observed in M. tuberculosis samples. In conclusion, it was successfully shown in this study that it is possible to diagnose Sri Lankan CL with high accuracy, to genus and species identification, using Leishmania DNA PCR assays. PMID:26676321

  12. The availability and validity of safety information of over the counter herbal products for use in diabetes in Sri Lanka: A cross sectional study

    PubMed Central

    Medagama, Arjuna Bandara; Widanapahirana, Heshan; Prasanga, Tharindu

    2015-01-01

    Aims: There is an increase of over-the-counter (OTC) herbal products for use in diabetes mellitus. The aim of this study is to evaluate the safety information provided with OTC herbal remedies intended for diabetic patients in Sri Lanka and to assess the completeness of the information provided. Methods: Inclusion criteria consisted of OTC herbal remedies meant for use in diabetes. They were bought from local Sri Lankan supermarkets and non-ayurvedic pharmacies and product information regarding the risk of hypoglycemia, precautions for use, adverse events, dose, and interactions were assessed using a scoring system. The accuracy of the information was then compared against published data. Results: 11 products fulfilled the inclusion criteria. Five products contained a single constituent and five contained more than one. None had complete and accurate safety information according to our criteria. None specifically warned against the risk of hypoglycemia. 9 out of 11 products (81.8%) carried ≤3 items of the five essential factual information we expected. Hypoglycemic coma, gastrointestinal symptoms, hepatotoxicity, carcinogenesis, and interactions causing elevated drug levels of Carbamazepine were some of the safety information that was missing. Conclusions: Key safety information was absent in most products. Regulation of sale, provision of key safety information and adverse event reporting should be a priority. PMID:26649230

  13. A comparative study of venomics of Naja naja from India and Sri Lanka, clinical manifestations and antivenomics of an Indian polyspecific antivenom.

    PubMed

    Sintiprungrat, Kitisak; Watcharatanyatip, Kamolwan; Senevirathne, W D S T; Chaisuriya, Papada; Chokchaichamnankit, Daranee; Srisomsap, Chantragan; Ratanabanangkoon, Kavi

    2016-01-30

    Naja naja (Indian cobra) from Sri Lanka and India is the WHO Category 1 medically important snakes in both countries. Some antivenom produced against Indian N. naja (NNi) were less effective against Sri Lankan N. naja (NNsl). Proteomes of NNi and NNsl venoms were studied by RP-HPLC, SDS-PAGE and LC/MS/MS. Six protein families were identified in both venoms with the most abundant were the 3 finger toxins (3FTs) where cytotoxins (CTX) subtype predominated, followed by phospholipase A2, cysteine-rich venom protein, snake venom metalloproteases, venom growth factors, and protease inhibitors. Qualitative and quantitative differences in the venomics profiles were observed. Some proteins were isolated from either NNi or NNsl venom. Postsynaptic neurotoxins (NTX) were identified for the first time in NNsl venom. Thus, there are geographic intra-specific variations of venom composition of the two N. naja. The relative abundance of CTX and NTX explained well the clinical manifestations of these venoms. Antivenomics study of an Indian antivenom (Vins) showed the antibodies effectively bound all venom toxins from both snakes but more avidly to the Indian venom proteins. The lower antibody affinity towards the 'heterologous' venom was the likely cause of poor efficacy of the Indian antivenom used to treat NNsl envenoming. PMID:26506536

  14. Prevalence of Major Depressive Disorder Among Spouses of Men Who Use Alcohol in a Rural Community in Central Sri Lanka

    PubMed Central

    Ariyasinghe, Dewasmika; Abeysinghe, Ranil; Siriwardhana, Prabhash; Dassanayake, Tharaka

    2015-01-01

    Aims: To estimate the prevalence of major depressive disorder (MDD) among spouses of men who use alcohol in two rural areas in Sri Lanka, and to examine whether the severity of alcohol-related problems (ARPs) in men and presence of alcohol-related domestic violence are associated with MDD among these women. Method: In a cross-sectional study, ARPs among men were assessed using Alcohol Use Disorders Identification Test (AUDIT) questionnaire filled in by men, and domestic violence and husbands' drinking pattern data obtained from the women. MDD among the women was ascertained using the Structured Clinical Interview for DSM–IV Disorders for major depression. Using logistic regression we examined whether age, past history of depression, different indices of ARPs and domestic violence were associated with current MDD among the women. Results: Point prevalence of MDD in the sample was 33.3% (95% CI: 25.93, 40.73%). Once adjusted for other factors, morning drinking of the spouse (odds ratio = 4.11, 95% CI: 1.25, 13.47; P = 0.019) and increasing age (odds ratio = 1.05, 95% CI: 1.01, 1.09; P = 0.003) significantly increased the odds of MDD. Being subjected to domestic violence/arguments also had a trend to be associated with MDD among women, but was not significant (odds ratio = 2.29, 95% CI: 0.95, 5.48; P = 0.062). Conclusion: The prevalence of MDD among spouses of men who use alcohol is markedly higher than that has been observed among Sri Lankan women in previous studies. The prevalence of MDD in women seems to increase when their husbands are morning drinkers, and with increasing age. PMID:25589089

  15. Establishing a twin register in Sri Lanka.

    PubMed

    Sumathipala, A; Fernando, D J; Siribaddana, S H; Abeysingha, M R; Jayasekare, R W; Dissanayake, V H; De Silva, N

    2000-12-01

    Nearly all twin registers are based in developed countries and there is no twin register in the developing world. Our objectives were to initiate the process of establishing a nationwide twin register in Sri Lanka by starting a volunteer register first and working towards a population-based register. Regular newspaper advertisements, feature articles, radio talks, and television programmes were used to publicise a competition for twins, their parents/relatives and friends requesting them to participate by sending in details of twins. The competition ran from 28 March 1997 for a period of 3 months. It offered prizes for three winners selected by drawing lots. Advertisements highlighted the objective of the competition as establishing a twin register for future research and emphasised that informed consent would be obtained for individual research projects. Those who registered comprise 4602 twin pairs (same sex: male--1564, female--1885; different sex--1153), 80 sets of triplets (same sex: male--17, female--31; different sex--42) and two sets of quadruplets (different sex). The oldest twins, triplets, quadruplets are 85, 46, and 5 years old, respectively; 88.0% of twins are less than 30 years old. Although others have previously used media publicity to enrol twins in twin registers, we believe this to be the first time that twins have been enrolled through competition. We have more young twins, and our gender and zygosity proportions after applying Weinburg's rule do not match the proportions expected from a volunteer twin sample. Establishing a twin register for research purposes has proved possible in a developing country. PMID:11463139

  16. Norms for a neuropsychological test battery to diagnose dementia in the elderly: A study from Sri Lanka

    PubMed Central

    Srinivasan, Srikanth; Jaleel, Qadir

    2015-01-01

    Aims: To pilot a neuropsychological battery for diagnosing dementia and provide normative scores in an elderly Sri Lankan sample. Materials and Methods: Consecutive subjects over the age of 60 yrs were administered tests assessing the individual domains of language, verbal episodic memory, visual perceptuospatial skills and executive functions in the Sinhala language. Results: There were a total of 230 subjects in the final sample. The mean age of the entire sample was 69 years, mean education level was 12 years and the sample comprised 53% female. One-month test-retest reliability ranged from 0.71 to 0.85 for the various tests. Most tests were significantly influenced by age and education level but not gender. The exceptions to this were some language subtests (repetition, grammar comprehension and word picture matching) and two tests of executive functioning (maze completion and alternate target cancellation), which were uninfluenced by age. The subtests where ceiling performance was attained by almost all subjects were repetition, grammar comprehension and word picture matching from the language domain, dot position discrimination from the visuospatial domain and maze completion test from the executive function domain. Scores for various tests after stratifying subjects by age and educational level are given. Conclusions: The tests were well received and could provide a basis for cognitive profiling in similar settings elsewhere. PMID:25883476

  17. Neuromuscular Effects of Common Krait (Bungarus caeruleus) Envenoming in Sri Lanka

    PubMed Central

    Silva, Anjana; Maduwage, Kalana; Sedgwick, Michael; Pilapitiya, Senaka; Weerawansa, Prasanna; Dahanayaka, Niroshana J.; Buckley, Nicholas A.; Johnston, Christopher; Siribaddana, Sisira; Isbister, Geoffrey K.

    2016-01-01

    Objective We aimed to investigate neurophysiological and clinical effects of common krait envenoming, including the time course and treatment response. Methodology Patients with definite common krait (Bungarus caeruleus) bites were recruited from a Sri Lankan hospital. All patients had serial neurological examinations and stimulated concentric needle single-fibre electromyography (sfEMG) of orbicularis oculi in hospital at 6wk and 6–9mth post-bite. Principal Findings There were 33 patients enrolled (median age 35y; 24 males). Eight did not develop neurotoxicity and had normal sfEMG. Eight had mild neurotoxicity with ptosis, normal sfEMG; six received antivenom and all recovered within 20–32h. Seventeen patients developed severe neurotoxicity with rapidly descending paralysis, from ptosis to complete ophthalmoplegia, facial, bulbar and neck weakness. All 17 received Indian polyvalent antivenom a median 3.5h post-bite (2.8–7.2h), which cleared unbound venom from blood. Despite this, the paralysis worsened requiring intubation and ventilation within 7h post-bite. sfEMG showed markedly increased jitter and neuromuscular blocks within 12h. sfEMG abnormalities gradually improved over 24h, corresponding with clinical recovery. Muscle recovery occurred in ascending order. Myotoxicity was not evident, clinically or biochemically, in any of the patients. Patients were extubated a median 96h post-bite (54–216h). On discharge, median 8 days (4–12days) post-bite, patients were clinically normal but had mild sfEMG abnormalities which persisted at 6wk post-bite. There were no clinical or neurophysiological abnormalities at 6–9mth. Conclusions Common krait envenoming causes rapid onset severe neuromuscular paralysis which takes days to recover clinically consistent with sfEMG. Subclinical neuromuscular dysfunction lasts weeks but was not permanent. Antivenom effectively cleared venom but did not prevent worsening or reverse neuromuscular paralysis. PMID:26829229

  18. Vulnerability assessment and protective effects of coastal vegetation during the 2004 Tsunami in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Kaplan, M.; Renaud, F. G.; Lüchters, G.

    2009-08-01

    The tsunami of December 2004 caused extensive human and economic losses along many parts of the Sri Lankan coastline. Thanks to extensive national and international solidarity and support in the aftermath of the event, most people managed to restore their livelihoods completely but some households did not manage to recover completely from the impacts of the event. The differential in recovery highlighted the various vulnerabilities and coping capacities of communities exposed to the tsunami. Understanding the elements causing different vulnerabilities is crucial to reducing the impact of future events, yet capturing them comprehensively at the local level is a complex task. This research was conducted in a tsunami-affected area in southwestern Sri Lanka to evaluate firstly the role of coastal vegetation in buffering communities against the tsunami and secondly to capture the elements of vulnerability of affected communities. The area was chosen because of its complex landscape, including the presence of an inlet connecting the Maduganga estuary with the sea, and because of the presence of remaining patches of coastal vegetation. The vulnerability assessment was based on a comprehensive vulnerability framework and on the Sustainable Livelihoods Framework in order to detect inherent vulnerabilities of different livelihood groups. Our study resulted in the identification of fishery and labour-led households as the most vulnerable groups. Unsurprisingly, analyses showed that damages to houses and assets decreased quickly with increasing distance from the sea. It could also be shown that the Maduganga inlet channelled the energy of the waves, so that severe damages were observed at relatively large distances from the sea. Some reports after the tsunami stated that mangroves and other coastal vegetation protected the people living behind them. Detailed mapping of the coastal vegetation in the study area and subsequent linear regression revealed significant differences

  19. Cost-effectiveness analyses of self-harm strategies aimed at reducing the mortality of pesticide self-poisonings in Sri Lanka: a study protocol

    PubMed Central

    Madsen, Lizell Bustamante; Eddleston, Michael; Hansen, Kristian Schultz; Pearson, Melissa; Agampodi, Suneth; Jayamanne, Shaluka; Konradsen, Flemming

    2015-01-01

    Introduction An estimated 803 900 people worldwide died as a result of self-harm in 2012. The deliberate ingestion of pesticides has been identified as the method most frequently used to commit fatal self-harm globally. In Sri Lanka, it is estimated that up to 60% of all suicides are committed using this method. The aim of the present study is to assess the cost-effectiveness of an ongoing safe storage intervention currently taking place in a rural Sri Lankan district and to model the cost-effectiveness of implementing the safe storage intervention as well as four potential interventions (legislative, medical management, follow-up contact and mobile phone contact) on a national level. Methods and analysis Study design for all the strategies is a cost-effectiveness analysis. A governmental perspective is adopted. The time horizon for tracking the associated costs and health outcomes of the safe storage intervention on district level runs over 3 years. The time horizon is extended to 5 years when modelling a full national roll-out of the respective interventions. The discounting of costs and health outcomes are undertaken at the recommended real rate of 3%. Threshold analyses of the modelled strategies are employed to assess the strategies potential for cost-effectiveness, running scenarios with health outcome improvements ranging from 1% to 100%. Sensitivity analyses are also performed. The main outcome measures of the safe storage intervention are incremental cost-effectiveness ratios. Ethics and dissemination Ethical approval was granted for the safe storage project from the University of Peradeniya, Sri Lanka, in March of 2008. An amendment for the present study was granted from Rajarata University of Sri Lanka in November of 2013. Findings will be disseminated to public and private stakeholders in local and national government in Sri Lanka as well as the wider academic audience through peer-reviewed publications and international conferences. Trial

  20. Lyssavirus in Indian Flying Foxes, Sri Lanka

    PubMed Central

    Gunawardena, Panduka S.; Marston, Denise A.; Ellis, Richard J.; Wise, Emma L.; Karawita, Anjana C.; Breed, Andrew C.; McElhinney, Lorraine M.; Johnson, Nicholas; Banyard, Ashley C.

    2016-01-01

    A novel lyssavirus was isolated from brains of Indian flying foxes (Pteropus medius) in Sri Lanka. Phylogenetic analysis of complete virus genome sequences, and geographic location and host species, provides strong evidence that this virus is a putative new lyssavirus species, designated as Gannoruwa bat lyssavirus. PMID:27434858

  1. Management for Educational Development in Sri Lanka.

    ERIC Educational Resources Information Center

    Fernando, Neil, Ed.

    This document reports on 4 broad action programs, constituting a total of 15 projects, in 4 pilot districts in Sri Lanka. The programs, part of a larger effort by the Ministry of Education to actualize policy guidelines, have been attempts to bridge gaps between the capability and efficiency of the established school system and the multiple levels…

  2. Lyssavirus in Indian Flying Foxes, Sri Lanka.

    PubMed

    Gunawardena, Panduka S; Marston, Denise A; Ellis, Richard J; Wise, Emma L; Karawita, Anjana C; Breed, Andrew C; McElhinney, Lorraine M; Johnson, Nicholas; Banyard, Ashley C; Fooks, Anthony R

    2016-08-01

    A novel lyssavirus was isolated from brains of Indian flying foxes (Pteropus medius) in Sri Lanka. Phylogenetic analysis of complete virus genome sequences, and geographic location and host species, provides strong evidence that this virus is a putative new lyssavirus species, designated as Gannoruwa bat lyssavirus. PMID:27434858

  3. The SRI24 multichannel atlas of normal adult human brain structure.

    PubMed

    Rohlfing, Torsten; Zahr, Natalie M; Sullivan, Edith V; Pfefferbaum, Adolf

    2010-05-01

    This article describes the SRI24 atlas, a new standard reference system of normal human brain anatomy, that was created using template-free population registration of high-resolution magnetic resonance images acquired at 3T in a group of 24 normal control subjects. The atlas comprises anatomical channels (T1, T2, and proton density weighted), diffusion-related channels (fractional anisotropy, mean diffusivity, longitudinal diffusivity, mean diffusion-weighted image), tissue channels (CSF probability, gray matter probability, white matter probability, tissue labels), and two cortical parcellation maps. The SRI24 atlas enables multichannel atlas-to-subject image registration. It is uniquely versatile in that it is equally suited for the two fundamentally different atlas applications: label propagation and spatial normalization. Label propagation, herein demonstrated using diffusion tensor image fiber tracking, is enabled by the increased sharpness of the SRI24 atlas compared with other available atlases. Spatial normalization, herein demonstrated using data from a young-old group comparison study, is enabled by its unbiased average population shape property. For both propagation and normalization, we also report the results of quantitative comparisons with seven other published atlases: Colin27, MNI152, ICBM452 (warp5 and air12), and LPBA40 (SPM5, FLIRT, AIR). Our results suggest that the SRI24 atlas, although based on 3T MR data, allows equally accurate spatial normalization of data acquired at 1.5T as the comparison atlases, all of which are based on 1.5T data. Furthermore, the SRI24 atlas is as suitable for label propagation as the comparison atlases and detailed enough to allow delineation of anatomical structures for this purpose directly in the atlas. PMID:20017133

  4. The SRI24 Multi-Channel Atlas of Normal Adult Human Brain Structure

    PubMed Central

    Rohlfing, Torsten; Zahr, Natalie M.; Sullivan, Edith V.; Pfefferbaum, Adolf

    2010-01-01

    This paper describes the SRI24 atlas, a new standard reference system of normal human brain anatomy, that was created using template-free population registration of high-resolution magnetic resonance images acquired at 3T in a group of 24 normal control subjects. The atlas comprises anatomical channels (T1, T2, and proton density weighted), diffusion-related channels (fractional anisotropy, mean diffusivity, longitudinal diffusivity, mean diffusion-weighted image), tissue channels (CSF probability, gray matter probability, white matter probability, tissue labels), and two cortical parcellation maps. The SRI24 atlas enables multi-channel atlas-to-subject image registration. It is uniquely versatile in that it is equally suited for the two fundamentally different atlas applications: label propagation and spatial normalization. Label propagation, herein demonstrated using DTI fiber tracking, is enabled by the increased sharpness of the SRI24 atlas compared with other available atlases. Spatial normalization, herein demonstrated using data from a young-old group comparison study, is enabled by its unbiased average population shape property. For both propagation and normalization, we also report the results of quantitative comparisons with seven other published atlases: Colin27, MNI152, ICBM452 (warp5 and air12), and LPBA40 (SPM5, FLIRT, AIR). Our results suggest that the SRI24 atlas, although based on 3T MR data, allows equally accurate spatial normalization of data acquired at 1.5T as the comparison atlases, all of which are based on 1.5T data. Furthermore, the SRI24 atlas is as suitable for label propagation as the comparison atlases and detailed enough to allow delineation of anatomical structures for this purpose directly in the atlas. PMID:20017133

  5. Global analysis of genetic variation in human arsenic (+ 3 oxidation state) methyltransferase (AS3MT)

    SciTech Connect

    Fujihara, Junko; Soejima, Mikiko; Yasuda, Toshihiro; Koda, Yoshiro; Agusa, Tetsuro; Kunito, Takashi; Tongu, Miki; Yamada, Takaya; Takeshita, Haruo

    2010-03-15

    Human arsenic (+ 3 oxidation state) methyltransferase (AS3MT) is known to catalyze the methylation of arsenite. The objective of this study was to investigate the diversity of the AS3MT gene at the global level. The distribution of 18 single nucleotide polymorphisms (SNPs) in AS3MT was performed in 827 individuals from 10 populations (Japanese, Korean, Chinese, Mongolian, Tibetans, Sri Lankan Tamils, Sri Lankan Sinhalese, Nepal Tamangs, Ovambo, and Ghanaian). In the African populations, the A allele in A6144T was not observed; the allele frequencies of C35587 were much lower than those in other populations; the allele frequencies of A37616 and C37950 were relatively higher than those in other populations. Among Asian populations, Mongolians showed a different genotype distribution pattern. A lower C3963 and T6144 frequencies were observed, and, in the C37616A and T37950C polymorphism, the Mongolian population showed higher A37616 and C37950 allele frequencies than other Asian populations, similarly to the African populations. A total of 66 haplotypes were observed in the Ovambo, 48, in the Ghanaian, 99, in the Japanese, 103, in the Korean, 103, in the South Chinese, 20, in the Sri Lankan Tamil, 12, in the Sri Lankan Sinhalese, 21, in the Nepal Tamang, 50, in the Tibetan, and 45, in the Mongolian populations. The D' values between the SNP pairs were extremely high in the Sri Lankan Sinhalese population. Relatively higher D' values were observed in Mongolian and Sri Lankan Tamil populations. Network analysis showed two clusters that may have different origins, African and Asians (Chinese and/or Japanese). The present study is the first to demonstrate the existence of genetic heterogeneity in a world wide distribution of 18 SNPs in AS3MT.

  6. The 2004 December 26 Indian Ocean tsunami impact on Sri Lanka: cascade modelling from ocean to city scales

    NASA Astrophysics Data System (ADS)

    Poisson, B.; Garcin, M.; Pedreros, R.

    2009-06-01

    The 2004 December 26 Indian Ocean tsunami severely hit Sri Lanka. Although it was not in the direct path of the initial tsunami waves, the western coast was struck by diffracted waves that caused much damage. The numerical model GEOWAVE is used to compute tsunami generation, propagation and inundation from the earthquake source to the Sri Lankan coast. A nested grid system is constructed to increase the resolution until Galle Bay, on the southwestern coast, where a 20 m-grid is used. The six nested topobathymetric grids are interpolated from ETOPO2 and high resolution data, at sea as onshore. Simulation results are compared with tsunami height data from National Oceanic and Atmospheric Administration (NOAA; US) and Geological Survey & Mines Bureau (GSMB; Sri Lanka). When the grid resolution increases, the discrepancy between the model and the data remains, on average, good, whereas its spread increases. We then conclude that the order of magnitude of the tsunami height is consistent from the 180 m-resolution grid, but the spatial imprecision is too high to locally predict reliable water heights. Nevertheless, the comparison between computed time-series of sea surface elevation at the Colombo tide station and tide-gauge data shows a very good agreement as both amplitude, and arrival time of the first wave are well reproduced. When focusing onshore, the modelled inundation limit is compared with the limit measured in the field. With its a priori setup, computed inundation spreads much farther behind the field limit. We then integrate more accurate nearshore conditions into the model. Non-linear shallow water equations are chosen instead of fully non-linear Boussinesq equations; the bottom friction on land is increased to a much higher value than at sea; the buildings cover and the low tide conditions are taken into account in the DEM. The resulting high resolution simulation agrees better with field data, even if discrepancies are still locally observed in places of

  7. The concurrent association of inflammatory polymyositis and Crohn’s ileo-colitis in a Sri Lankan man: a case report of a rare association and literature review

    PubMed Central

    2014-01-01

    Background Crohn’s disease is a relapsing, systemic inflammatory disease affecting the gastrointestinal tract with associated extraintestinal manifestations and immune disorders. Among the few cases reported, the association of Crohn’s disease with polymyositis varies in its complexity and severity. We report here the first known case of inflammatory polymyositis leading to rhabdomyolysis in a male patient diagnosed with Crohn’s ileocolitis. Case presentation A 42-year-old previously healthy man presented with acute polymyositis leading to rhabdomyolysis. The acute nature of the illness raised the suspicion of an infective, toxic, or metabolic insult, which was excluded during further investigations. Prolonged low-grade fever and raised inflammatory markers led to the suspicion of inflammatory polymyositis, which was confirmed by electromyography and muscle histology. In the absence of an infective cause, the concurrent association of prolonged diarrhea containing blood and mucous after recovery from an acute phase of myositis proved a diagnostic challenge. Ileocolonoscopy findings of extensive aphthous ulceration with skip lesions extending to the terminal ileum, and histology showing polymorph infiltration of the lamina propria, transmural involvement, and micro abscess formation was suggestive of Crohn’s disease. Sensory motor axonal peripheral neuropathy, which is another rare association of inflammatory bowel disease, was also present. Conclusion An unrecognized genetic predisposition or altered gut permeability causing disruption of the gut immune barrier triggering an immune response against skeletal muscles may have contributed to this unique association. Both polymyositis and Crohn’s ileocolitis responded well to corticosteroids and azathioprine, which is supportive of their immune pathogenesis. Myositis can be considered to be a rare extraintestinal manifestation of Crohn’s disease and can be used in the differential diagnosis of corticosteroid or hypokalemia-induced myopathy in Crohn’s disease. PMID:24552185

  8. Mithuri users surveyed in Sri Lanka.

    PubMed

    1983-01-01

    The Family Planning Association (FPA) of Sri Lanka completed a survey of Mithuri (oral contraceptive) users to determine consumer characteristics. The survey addressed issues such as purchasing habits, user patterns, dealer consumer relationships, levels of consumer satisfaction and motivation, prevalence of side effects, degree and level of medical consultations, and attitudes toward mass media product advertising. A mail survey was used to conduct this quantitative research to reduce the cost of collecting the data. Mail surveys offer the advantage of being able to reach a large number of respondents at a very reasonable cost, but they also require an accurate list of respondents who are representative of the population to be examined. Of the 681 questionnaires delivered, 442 were completed and returned. The majority of those surveyed (86%) purchased Mithuri at pharmacies that are within 5 miles of their residence. 73.2% of the women asked their husbands to make the purchase, and 67.6% purchased 2 cycles at a time. Most respondents reported experiencing no side effects from Mithuri. The majority of the few who experienced side effects considered them to be very slight. 2.7% of the respondents reported becoming pregnant while using Mithuri, 11 of whom ascribed the pregnancy to their failure to take the pill regularly. Most respondents said that they never missed a day. Husbands or "Western" medical practitioners were most often cited as the motivators to use Mithuri. Of the 82% of the respondents who had read the Mithuri newspaper advertisements, 87% indicated they approved of mass media advertising about contraceptives, primarily because they felt that making such information available was an urgent matter. Although advertisements and package circulars urged 1st time users to consult a physician before using Mithuri, less than half the respondents reported consulting any medical person, nurses, and midwives included. They also reported that the dealer gave no

  9. The Effectiveness of a ‘Train the Trainer’ Model of Resuscitation Education for Rural Peripheral Hospital Doctors in Sri Lanka

    PubMed Central

    Rajapakse, Bishan N.; Neeman, Teresa; Dawson, Andrew H.

    2013-01-01

    Background Sri Lankan rural doctors based in isolated peripheral hospitals routinely resuscitate critically ill patients but have difficulty accessing training. We tested a train-the-trainer model that could be utilised in isolated rural hospitals. Methods Eight selected rural hospital non-specialist doctors attended a 2-day instructor course. These “trained trainers” educated their colleagues in advanced cardiac life support at peripheral hospital workshops and we tested their students in resuscitation knowledge and skills pre and post training, and at 6- and 12-weeks. Knowledge was assessed through 30 multiple choice questions (MCQ), and resuscitation skills were assessed by performance in a video recorded simulated scenario of a cardiac arrest using a Resuci Anne Skill Trainer mannequin. Results/Discussion/Conclusion Fifty seven doctors were trained. Pre and post training assessment was possible in 51 participants, and 6-week and 12-week follow up was possible for 43, and 38 participants respectively. Mean MCQ scores significantly improved over time (p<0.001), and a significant improvement was noted in “average ventilation volume”, “compression count”, and “compressions with no error”, “adequate depth”, “average depth”, and “compression rate” (p<0.01). The proportion of participants with compression depth ≥40mm increased post intervention (p<0.05) and at 12-week follow up (p<0.05), and proportion of ventilation volumes between 400-1000mls increased post intervention (p<0.001). A significant increase in the proportion of participants who “checked for responsiveness”, “opened the airway”, “performed a breathing check”, who used the “correct compression ratio”, and who used an “appropriate facemask technique” was also noted (p<0.001). A train-the-trainer model of resuscitation education was effective in improving resuscitation knowledge and skills in Sri Lankan rural peripheral hospital doctors. Improvement was

  10. Assessing sloth bears as surrogates for carnivore conservation in Sri Lanka

    USGS Publications Warehouse

    Ratnayeke, Shyamala; Van Manen, Frank T.

    2012-01-01

    Bears are large, charismatic mammals whose presence often garners conservation attention. Because healthy bear populations typically require large, contiguous areas of habitat, land conservation actions often are assumed to benefit co-occurring species, including other mammalian carnivores. However, we are not aware of an empirical test of this assumption. We used remote camera data from 2 national parks in Sri Lanka to test the hypothesis that the frequency of detection of sloth bears (Melursus ursinus) is associated with greater richness of carnivore species. We focused on mammalian carnivores because they play a pivotal role in the stability of ecological communities and are among Sri Lanka's most endangered species. Seven of Sri Lanka's carnivores are listed as endangered, vulnerable, or near threatened, and little empirical information exists on their status and distribution. During 2002–03, we placed camera traps at 152 sites to document carnivore species presence. We used Poisson regression to develop predictive models for 3 categories of dependent variables: species richness of (1) all carnivores, (2) carnivores considered at risk, and (3) carnivores of least conservation concern. For each category, we analyzed 8 a priori models based on combinations of sloth bear detections, sample year, and study area and used Akaike's information criterion (AICc) to test our research hypothesis. We detected sloth bears at 55 camera sites and detected 13 of Sri Lanka's 14 Carnivora species. Species richness of all carnivores showed positive associations with the number of sloth bear detections, regardless of study area. Sloth bear detections were also positively associated with species richness of carnivores at risk across both study years and study areas, but not with species richness of common carnivores. Sloth bears may serve as a valuable surrogate species whose habitat protection would contribute to conservation of other carnivores in Sri Lanka.

  11. Situation Report--Australia, The Gambia, Papua and New Guinea, Rhodesia, Sri Lanka, Taiwan, Tanzania, Tonga, and Western Samoa.

    ERIC Educational Resources Information Center

    International Planned Parenthood Federation, London (England).

    Data relating to population and family planning in nine foreign countries are presented in these situation reports. Countries included are Australia, The Gambia, Papua and New Guinea, Rhodesia, Sri Lanka, Taiwan, Tanzania, Tonga, and Western Somoa. Information is provided under three topics, statistical information, general background information,…

  12. Supporting elephant conservation in Sri Lanka through MODIS imagery

    NASA Astrophysics Data System (ADS)

    Perera, Kithsiri; Tateishi, Ryutaro

    2012-10-01

    The latest national elephant survey of Sri Lanka (2011) revealed Sri Lanka has 5,879 elephants. The total forest cover for these elephants is about 19,500 sq km (2012 estimation) and estimated forest area is about 30% of the country when smaller green patches are also counted. However, studies have pointed out that a herd of elephants need about a 100 sq km of forest patch to survive. With a high human population density (332 people per sq km, 2010), the pressure for land to feed people and elephants is becoming critical. Resent reports have indicated about 250 elephants are killed annually by farmers and dozens of people are also killed by elephants. Under this context, researchers are investigating various methods to assess the elephant movements to address the issues of Human-Elephant-Conflict (HEC). Apart from various local remedies for the issue, the conservation of elephant population can be supported by satellite imagery based studies. MODIS sensor imagery can be considered as a successful candidate here. Its spatial resolution is low (250m x 250m) but automatically filters out small forest patches in the mapping process. The daily imagery helps to monitor temporal forest cover changes. This study investigated the background information of HEC and used MODIS 250m imagery to suggest applicability of satellite data for Elephant conservations efforts. The elephant movement information was gathered from local authorities and potentials to identify bio-corridors were discussed. Under future research steps, regular forest cover monitoring through MODIS data was emphasized as a valuable tool in elephant conservations efforts.

  13. Abortion in Sri Lanka: The Double Standard

    PubMed Central

    2013-01-01

    In Sri Lanka, women do not have access to legal abortion except under life-saving circumstances. Clandestine abortion services are, however, available and quite accessible. Although safe specialist services are available to women who can afford them, others access services under unsafe and exploitative conditions. At the time of this writing, a draft bill that will legalize abortion in instances of rape, incest, and fetal abnormalities awaits approval, amid opposition. In this article, I explore the current push for legal reform as a solution to unsafe abortion. Although a welcome effort, this amendment alone will be insufficient to address the public health consequences of unsafe abortion in Sri Lanka because most women seek abortions for other reasons. Much broader legal and policy reform will be required. PMID:23327236

  14. Abortion in Sri Lanka: the double standard.

    PubMed

    Kumar, Ramya

    2013-03-01

    In Sri Lanka, women do not have access to legal abortion except under life-saving circumstances. Clandestine abortion services are, however, available and quite accessible. Although safe specialist services are available to women who can afford them, others access services under unsafe and exploitative conditions. At the time of this writing, a draft bill that will legalize abortion in instances of rape, incest, and fetal abnormalities awaits approval, amid opposition. In this article, I explore the current push for legal reform as a solution to unsafe abortion. Although a welcome effort, this amendment alone will be insufficient to address the public health consequences of unsafe abortion in Sri Lanka because most women seek abortions for other reasons. Much broader legal and policy reform will be required. PMID:23327236

  15. SGF29 and Sry pathway in hepatocarcinogenesis

    PubMed Central

    Kurabe, Nobuya; Murakami, Shigekazu; Tashiro, Fumio

    2015-01-01

    Deregulated c-Myc expression is a hallmark of many human cancers. We have recently identified a role of mammalian homolog of yeast SPT-ADA-GCN5-acetyltransferas (SAGA) complex component, SAGA-associated factor 29 (SGF29), in regulating the c-Myc overexpression. Here, we discuss the molecular nature of SFG29 in SPT3-TAF9-GCN5-acetyltransferase complex, a counterpart of yeast SAGA complex, and the mechanism through which the elevated SGF29 expression contribute to oncogenic potential of c-Myc in hepatocellularcarcinoma (HCC). We propose that the upstream regulation of SGF29 elicited by sex-determining region Y (Sry) is also augmented in HCC. We hypothesize that c-Myc elevation driven by the deregulated Sry and SGF29 pathway is implicated in the male specific acquisition of human HCCs. PMID:26322172

  16. Forecasts of Agricultural Drought in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Gilligan, J. M.; Gunda, T.; Hornberger, G. M.

    2015-12-01

    As the most frequent natural disaster in Sri Lanka, drought greatly affects crop production and livelihoods. Over half of all agricultural crop damage in Sri Lanka is currently due to drought; the frequency and severity of drought in the country is only expected to increase with the changing climate. Previous work indicates that the Palmer Drought Severity Index (PDSI) and Standardized Precipitation Index (SPI) are capable of capturing agricultural drought patterns (between 1881-2010) in the island nation. In this work, PDSI and SPI from 13 long-term meteorological stations will be projected into the future using a combination of artificial neural network and autoregressive integrated moving average models. The impacts of large-scale atmospheric circulation patterns (such as the Niño 3.4 index, a measure of sea surface temperature) and lead times on projection accuracy will also be explored. Model projections will be compared to weather data since 2010 to determine if the 2014 drought could have been forecasted using these methods. Since agricultural systems are strongly influenced by both natural and human systems, it is important to frame these physical findings within a social context. This work is part of an interdisciplinary project that assesses the perceptions of and adaptations to drought by rice farmers in Sri Lanka; disciplines represented in the group include hydrology, social psychology, ethnography, policy, and behavioral economics. Insights from the diverse research perspectives within the group will be drawn upon to highlight the social implications of the physical results.

  17. A Case of SRY-Positive 38,XY True Hermaphroditism (XY Sex Reversal) in a Cat

    PubMed Central

    Schlafer, D. H.; Valentine, B.; Fahnestock, G.; Froenicke, L.; Grahn, R. A.; Lyons, L. A.; Meyers-Wallen, V. N.

    2012-01-01

    Investigation of abnormal sexual development in companion animals can allow for the elimination of inherited disorders from breeding populations while contributing to the understanding of the complex process of mammalian sexual development and differentiation. A 1-year-old mixed-breed cat, presented for neutering, was tentatively diagnosed as a male with bilateral cryptorchidism. During surgery, the surgeon identified gonads in an ovarian position and a complete bicornuate uterus. Both testicular and ovarian architecture in the gonads and Mullerian and Wolffian duct derivatives were identified histologically. The karyotype was that of a normal male (38,XY), and no causative mutation was identified in the feline SRY coding sequence amplified from genomic DNA. All features of the case were compatible with a diagnosis of SRY-positive 38,XY sex reversal, true hermaphrodite phenotype. To the authors’ knowledge, this is the first report of this disorder in a domestic cat. PMID:20861501

  18. Seroprevalence of Toxoplasma gondii in cats from Colombo, Sri Lanka

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Cats are essential in the life cycle of Toxoplasma gondii because they are the only hosts that can excrete the environmentally-resistant oocysts in nature. Nothing is known of the prevalence of Toxoplasma gondii in cats from Sri Lanka. Serum samples from 86 cats from Colombo, Sri Lanka were tested f...

  19. The sri chakra as a symbol of the human body.

    PubMed

    Krishnakumar, P R

    1993-01-01

    Sri Chakra is the celebrated Yantra used in the worship of the primordial energy. The Chakra is conceived as a symbol of the human body. Some salient features of this symbolism are discussed in this article. An attempt has also been made to provide a short introduction to the Bhavanopanishad Prayogavidhi devised by Bhaskararaya, the doyen of Sri charka worshippers. PMID:22556608

  20. The University System of Sri Lanka. Vision and Reality. ICES Sri Lanka Studies Series.

    ERIC Educational Resources Information Center

    de Silva, K. M., Ed.; Peiris, G. H., Ed.

    This book reviews the history of university education in Sri Lanka, paying special attention to the University of Peradeniya, originally the University of Ceylon. The book focuses on how an institution of higher learning, modeled initially on the older universities of Britain, has been influenced by the challenges and constraints of continuing…

  1. Mapping the Risk of Snakebite in Sri Lanka - A National Survey with Geospatial Analysis

    PubMed Central

    Ediriweera, Dileepa Senajith; Kasturiratne, Anuradhani; Pathmeswaran, Arunasalam; Gunawardena, Nipul Kithsiri; Wijayawickrama, Buddhika Asiri; Jayamanne, Shaluka Francis; Isbister, Geoffrey Kennedy; Dawson, Andrew; Giorgi, Emanuele; Diggle, Peter John; Lalloo, David Griffith; de Silva, Hithanadura Janaka

    2016-01-01

    Background There is a paucity of robust epidemiological data on snakebite, and data available from hospitals and localized or time-limited surveys have major limitations. No study has investigated the incidence of snakebite across a whole country. We undertook a community-based national survey and model based geostatistics to determine incidence, envenoming, mortality and geographical pattern of snakebite in Sri Lanka. Methodology/Principal Findings The survey was designed to sample a population distributed equally among the nine provinces of the country. The number of data collection clusters was divided among districts in proportion to their population. Within districts clusters were randomly selected. Population based incidence of snakebite and significant envenoming were estimated. Model-based geostatistics was used to develop snakebite risk maps for Sri Lanka. 1118 of the total of 14022 GN divisions with a population of 165665 (0.8%of the country’s population) were surveyed. The crude overall community incidence of snakebite, envenoming and mortality were 398 (95% CI: 356–441), 151 (130–173) and 2.3 (0.2–4.4) per 100000 population, respectively. Risk maps showed wide variation in incidence within the country, and snakebite hotspots and cold spots were determined by considering the probability of exceeding the national incidence. Conclusions/Significance This study provides community based incidence rates of snakebite and envenoming for Sri Lanka. The within-country spatial variation of bites can inform healthcare decision making and highlights the limitations associated with estimates of incidence from hospital data or localized surveys. Our methods are replicable, and these models can be adapted to other geographic regions after re-estimating spatial covariance parameters for the particular region. PMID:27391023

  2. Self poisoning in Sri Lanka: motivational aspects.

    PubMed

    Hettiarachchi, J; Kodituwakku, G C

    1989-01-01

    Sri Lanka is a developing Asian country with high suicide rate due to self poisoning, related to a high fatality rate. A study of motivational aspects of self poisoning in 97 consecutive patients showed that there is no greater intention of suicide in them than those from the developed countries. Interpersonal disputes involving domestic problems and love affairs are the main precipitating causes. Improving family relations may help in the prevention of self-poisoning. However the impulsive nature of the act might prove prevention a difficult task. PMID:2767925

  3. Population.

    ERIC Educational Resources Information Center

    King, Pat; Landahl, John

    This pamphlet has been prepared in response to a new problem, a rapidly increasing population, and a new need, population education. It is designed to help teachers provide their students with some basic population concepts with stress placed on the elements of decision making. In the first section of the pamphlet, some of the basic concepts of…

  4. A descriptive profile of β-thalassaemia mutations in India, Pakistan and Sri Lanka.

    PubMed

    Black, M L; Sinha, S; Agarwal, S; Colah, R; Das, R; Bellgard, M; Bittles, A H

    2010-09-01

    Thalassaemia is a common and debilitating autosomal recessive disorder affecting many populations in South Asia. To date, efforts to create a regional profile of β-thalassaemia mutations have largely concentrated on the populations of India. The present study updates and expands an earlier profile of β-thalassaemia mutations in India, and incorporates comparable data from Pakistan and Sri Lanka. Despite limited data availability, clear patterns of historical and cultural population movements were observed relating to major β-thalassaemia mutations. The current regional mutation profiles of β-thalassaemia have been influenced by historical migrations into and from the Indian sub-continent, by the development and effects of Hindu, Buddhist, Muslim and Sikh religious traditions, and by the major mid-twentieth century population translocations that followed the Partition of India in 1947. Given the resultant genetic complexity revealed by the populations of India, Pakistan and Sri Lanka, to ensure optimum diagnostic efficiency and the delivery of appropriate care, it is important that screening and counselling programmes for β-thalassaemia mutations recognise the underlying patterns of population sub-division throughout the region. PMID:22460247

  5. An Acoustic Analysis of the Genus Microhyla (Anura: Microhylidae) of Sri Lanka

    PubMed Central

    Wijayathilaka, Nayana

    2016-01-01

    Vocalizing behavior of frogs and toads, once quantified, is useful for systematics, rapid species identification, behavioral experimentation and conservation monitoring. But yet, for many lineages vocalizations remain unknown or poorly quantified, especially in diversity rich tropical regions. Here we provide a quantitative acoustical analysis for all four Sri Lankan congeners of the genus Microhyla. Three of these species are endemic to the island, but Microhyla ornata is regionally widespread. Two of these endemics, M. karunaratnei (Critically Endangered) and M. zeylanica (Endangered), are highly threatened montane isolates; the other, M. mihintalei, is relatively common across the dry lowlands. We recorded and analyzed 100 advertisement calls from five calling males for each species, except for M. zeylanica, which only had 53 calls from three males suitable for analyses. All four species call in choruses and their vocal repertoires are simple compared to most frogs. Their calls contain multiple pulses and no frequency modulation. We quantified eight call characters. Call duration and number of pulses were higher for the two montane isolates (inhabiting cooler habitats at higher altitudes) compared to their lowland congeners. Microhyla zeylanica has the longest call duration (of 1.8 ± 0.12 s) and the highest number of pulses (of 61–92 pulses). The smallest of the species, Microhyla karunaratnei (16.2–18.3 mm), has the highest mean dominant frequency (3.3 ± 0.14 kHz) and pulse rate (77 ± 5.8 pulses per second). The calls separate well in the Principal Component space: PC1 axis is mostly explained by the number of pulses per call and call duration; PC2 is mostly explained by the pulse rate. A canonical means plot of a Discriminant Function analysis shows non-overlapping 95% confidence ellipses. This suggests that some call parameters can be used to distinguish these species effectively. We provide detailed descriptions for eight call properties and compare

  6. An Acoustic Analysis of the Genus Microhyla (Anura: Microhylidae) of Sri Lanka.

    PubMed

    Wijayathilaka, Nayana; Meegaskumbura, Madhava

    2016-01-01

    Vocalizing behavior of frogs and toads, once quantified, is useful for systematics, rapid species identification, behavioral experimentation and conservation monitoring. But yet, for many lineages vocalizations remain unknown or poorly quantified, especially in diversity rich tropical regions. Here we provide a quantitative acoustical analysis for all four Sri Lankan congeners of the genus Microhyla. Three of these species are endemic to the island, but Microhyla ornata is regionally widespread. Two of these endemics, M. karunaratnei (Critically Endangered) and M. zeylanica (Endangered), are highly threatened montane isolates; the other, M. mihintalei, is relatively common across the dry lowlands. We recorded and analyzed 100 advertisement calls from five calling males for each species, except for M. zeylanica, which only had 53 calls from three males suitable for analyses. All four species call in choruses and their vocal repertoires are simple compared to most frogs. Their calls contain multiple pulses and no frequency modulation. We quantified eight call characters. Call duration and number of pulses were higher for the two montane isolates (inhabiting cooler habitats at higher altitudes) compared to their lowland congeners. Microhyla zeylanica has the longest call duration (of 1.8 ± 0.12 s) and the highest number of pulses (of 61-92 pulses). The smallest of the species, Microhyla karunaratnei (16.2-18.3 mm), has the highest mean dominant frequency (3.3 ± 0.14 kHz) and pulse rate (77 ± 5.8 pulses per second). The calls separate well in the Principal Component space: PC1 axis is mostly explained by the number of pulses per call and call duration; PC2 is mostly explained by the pulse rate. A canonical means plot of a Discriminant Function analysis shows non-overlapping 95% confidence ellipses. This suggests that some call parameters can be used to distinguish these species effectively. We provide detailed descriptions for eight call properties and compare these

  7. Climate Change Impacts on Rice Farming Systems in Northwestern Sri Lanka. Chapter 10

    NASA Technical Reports Server (NTRS)

    Zubair, Lareef; Nissanka, Sarath P.; Weerakoon, W. M. W.; Herath, Dumindu I.; Karunaratne, Asha S; Prabodha, A. S. M.; Agalawatte, M. B.; Herath, Rasnayaka; Yahiya, S. Zeenas; Punyawardhene, B. V. R.; Vishwanathan, Janan; Delpitiya, Punya; Wijekoon, A. Erandika N.; Gunaratna, Janaka; Chandrasekara, Sewwandhi S. K.; Wickramagamage, P.; Weerasinghe, K. D. N.; Navaratne, Champa M.; Perera, Ruchika S.; Gunesekara, Asela I.; Kumara, G. M. Pradeep; Wallach, Daniel; Valdivia, Roberto O.; McDermid, Sonali

    2015-01-01

    Sri Lanka has achieved tremendous progress since 1950 in crop production and food availability. Yields grew at an impressive rate until leveling off in the mid-eighties. Sri Lanka's population is anticipated to grow in the coming decades, creating an ever-greater demand for food security on the household, sub-district, regional, and national scales.The agricultural sector in Sri Lanka is vulnerable to climate shocks. An unusual succession of droughts and floods from 2008 to 2014 has led to both booms and busts in agricultural production, which were reflected in food prices. In both instances, the majority of farmers and consumers were adversely affected.At present the rice-farming systems are under stress due to inadequate returns for the farmers and difficulty in coping with shocks due to climate, pests, and diseases, and prices for produce. There are government price-support mechanisms, fertilizer-subsidy schemes, and crop insurance schemes, but the levels of the supports are modest and often do not effectively reach the farmers.

  8. Caregiving expectations and challenges among elders and their adult children in Southern Sri Lanka

    PubMed Central

    Watt, Melissa H.; Perera, Bilesha; Østbye, Truls; Ranabahu, Shyama; Rajapakse, Harshini; Maselko, Joanna

    2014-01-01

    The elderly population in Sri Lanka is growing rapidly. Elders are traditionally cared for in the homes of their adult children, but the shifting socio-economic environment in Sri Lanka challenges this arrangement. This paper describes the dynamics of elder-caregiver relationships in Southern Sri Lanka. Data included 4 focus group discussions and 5 in-depth interviews with elderly, and 10 in-depth interviews with adult children of the elderly. Discussion guide topics included caregiving arrangements, and roles/responsibilities of elders and caregivers. Using a grounded theory approach, a comprehensive analytic memo was developed and discussed to explore emerging themes on the caregiver dynamic. Both elders and caregivers felt that elders should be taken care of in the home by their children. They pointed to a sense of duty and role modeling of parental caregiving that is passed down through generations. Even as elders desired support from their children, they feared losing their independence, and saw financial autonomy as important for maintaining relationship balance. Caregiving challenges included: households where both the adult child and his/her spouse worked outside the home; households where elders had a disproportionate amount of household work; economically stressed households; and lack of direct communication between elders and caregivers regarding conflicts. Results point to strong values around caring for elderly in the home, but identify challenges to this arrangement in the future. PMID:25152553

  9. Characterization of imported malaria, the largest threat to sustained malaria elimination from Sri Lanka.

    PubMed

    Dharmawardena, Priyani; Premaratne, Risintha G; Gunasekera, W M Kumudunayana T de A W; Hewawitarane, Mihirini; Mendis, Kamini; Fernando, Deepika

    2015-01-01

    Sri Lanka has reached zero indigenous malaria cases in November 2012, two years before its targeted deadline for elimination. Currently, the biggest threat to the elimination efforts are the risk of resurgence of malaria due to imported cases. This paper describes two clusters of imported malaria infections reported in 2013 and 2014, one among a group of Pakistani asylum-seekers resident in Sri Lanka, and the other amongst local fishermen who returned from Sierra Leone. The two clusters studied reveal the potential impact of imported malaria on the risk of reintroducing the disease, as importation is the only source of malaria in the country at present. In the event of a case occurring, detection is a major challenge both amongst individuals returning from malaria endemic countries and the local population, as malaria is fast becoming a "forgotten" disease amongst health care providers. In spite of a very good coverage of diagnostic services (microscopy and rapid diagnostic tests) throughout the country, malaria is being repeatedly overlooked by health care providers even when individuals present with fever and a recent history of travel to a malaria endemic country. Given the high receptivity to malaria in previously endemic areas of the country due to the prevalence of the vector mosquito, such cases pose a significant threat for the reintroduction of malaria to Sri Lanka. The challenges faced by the Anti Malaria Campaign and measures taken to prevent the resurgence of malaria are discussed here. PMID:25902716

  10. The economic, demographic, sociocultural and political setting for emigration from Sri Lanka.

    PubMed

    Gunatilleke, G

    1995-01-01

    This study of emigration from Sri Lanka is introduced by a brief review of the situation during the colonial period and an overview of recent migration experience. The second section of the paper deals with data collection and sources for labor migration, political migration, and estimates of total net migration. The third section looks at economic and demographic trends in terms of the growth of the economy, population growth and social well-being, the growth of the labor force, unemployment, the structure of the work force, internal migration and access to agricultural lands, and income distribution and poverty. The sociocultural setting is then explored by considering exposure to the international environment, ethnicity and cultural affinity, the formation of information and job placement networks, the supportive role of the family, and the impact of success and failure. Moving on the influence of the political setting, the paper then discusses the government policy of foreign employment promotion as well as the influence of political developments on migration. In conclusion, the paper notes that future demand for domestic service workers will likely increase, and that Sri Lanka will continue to have a surplus of workers to fill this demand until the end of the 1990s, when a tightening domestic labor market and increased real wages will ease the push for migration. Political factors will continue to favor migration, however, unless a liberal democratic regime becomes the governing force in Sri Lanka. PMID:12347013

  11. Home ranges and habitat use of sloth bears Melursus ursinus inornatus in Wasgomuwa National Park, Sri Lanka

    USGS Publications Warehouse

    Ratnayeke, S.; Van Manen, F.T.; Padmalal, U.K.G.K.

    2007-01-01

    We studied home ranges and habitat selection of 10 adult sloth bears Melursus ursinus inornatus at Wasgomuwa National Park, Sri Lanka during 2002-2003. Very little is known about the ecology and behaviour of M. u. inornatus, which is a subspecies found in Sri Lanka. Our study was undertaken to assess space and habitat requirements typical of a viable population of M. u. inornatus to facilitate future conservation efforts. We captured and radio-collared 10 adult sloth bears and used the telemetry data to assess home-range size and habitat use. Mean 95% fixed kernel home ranges were 2.2 km2 (SE = 0.61) and 3.8 km2 (SE = 1.01) for adult females and males, respectively. Although areas outside the national park were accessible to bears, home ranges were almost exclusively situated within the national park boundaries. Within the home ranges, high forests were used more and abandoned agricultural fields (chenas) were used less than expected based on availability. Our estimates of home-range size are among the smallest reported for any species of bear. Thus, despite its relatively small size, Wasgomuwa National Park may support a sizeable population of sloth bears. The restriction of human activity within protected areas may be necessary for long-term viability of sloth bear populations in Sri Lanka as is maintenance of forest or scrub cover in areas with existing sloth bear populations and along potential travel corridors. ?? Wildlife Biology 2007.

  12. Investigations on Piper betle grown in Sri Lanka

    PubMed Central

    Arambewela, L. S. R.; Arawwawala, L. D. A. M.; Kumaratunga, K. G; Dissanayake, D. S; Ratnasooriya, W. D.; Kumarasingha, S. P.

    2011-01-01

    Piper betle is an economically important plant cultivated in Sri Lanka. Although more than 12 cultivars of betel are reported in Sri Lanka, very few scientific investigations have been carried out on them. Studies on the chemical constituents indicated that safrole is the major constituent, followed by chavibitol acetate, in the essential oil of common betel leaves of Sri Lanka. Investigations on the bioactivities of P. betle revealed the presence of antimicrobial, insecticidal, antioxidant, antinociceptive, antidiabetic and gastroprotective activities. In addition, P. betle was found to be safe in terms of hepatotoxicity, renotoxicity, hematotoxicity, gross morphology, weights of organs, stress or aversive behaviors in rats. The above findings indicate the vast potential of P. betle yet to be harnessed for the benefit of mankind and the betel industry of Sri Lanka. PMID:22279373

  13. Environmental and Socio-Demographic Determinants of Dengue Fever in Colombo City, Sri Lanka

    NASA Technical Reports Server (NTRS)

    Tipre, Meghan; Luvall, Jeffrey; Haque, Akhlaque; McClure, Leslie; Zaitchik, Ben; Sathiakumar, Nalini

    2014-01-01

    Dengue fever has increased exponentially in Sri Lanka, from 24.4 cases per 100,000 in 2003 to 165.3 per 100,000 population in 2013. Although early warning systems using predictor models have been previously developed in other settings, it is important to develop such models in each local setting. Further, the ability of these models to be applicable at smaller geographic units will enhance current vector control and disease surveillance measures. The aim of this paper was to identify environmental and socio-economic status (SES) risk factors that may predict dengue fever at the Gram Niladhari Divisions (GND) level (smallest administrative unit) in Colombo city, Sri Lanka. These factors included landcover classes, amount of vegetation, population density, water access and neighborhood SES as determined by roof type. A geographically weighted regression (GWR) was used to develop the prediction model. A total 55 GND units covering an area of 37 sq km were investigated. We found that GND units with decreased vegetation, higher built-up area, higher population density and poor access to tap-water supply were associated with high risk of dengue; the pertinent GND units were concentrated in the center of the city. This is the first study in Sri Lanka to include both environmental and socio-demographic factors in prediction models for dengue fever. The methodology may be useful in enhancing ongoing dengue fever control measures in the country, and to be extended to other countries in the region that have an increasing incidence of dengue fever.

  14. Human body donation programs in Sri Lanka: Buddhist perspectives.

    PubMed

    Subasinghe, Sandeepani Kanchana; Jones, D Gareth

    2015-01-01

    Considerable attention is being given to the availability of bodies for anatomical education. This raises the question of the manner in which they are obtained, that is, whether they are unclaimed or donated. With increasing emphasis upon the ethical desirability of using body bequests, the spotlight tends to be focused on those countries with factors that militate against donations. However, little attention has been paid to cultures where donations are readily available. One such country is Sri Lanka where the majority of the Buddhist population follows Theravada Buddhism. Within this context, the expectation is that donations will be given selflessly without expecting anything in return. This is because donation of one's body has blessings for a better outcome now and in the afterlife. The ceremonies to honor donors are outlined, including details of the "Pirith Ceremony." The relevance for other cultures of these features of body donation is discussed paying especial attention to the meaning of altruism and consent, and justification for the anonymization of cadavers. The degree to which anatomy is integrated into the surrounding culture also emerges as significant. PMID:25689145

  15. Problems of Illiteracy in a Literate Developing Society: Sri Lanka

    NASA Astrophysics Data System (ADS)

    Gunawardena, Chandra

    1997-09-01

    With 87.0% of its population literate, Sri Lanka occupies a high ranking position among South and South-East Asian nations in educational development. The high percentage of literacy achieved through progressive measures in education spanning half a century, however, has led to a state of complacency and less priority being given to efforts at eradicating illiteracy. This paper will focus on a recent study conducted on the incidence of illiteracy in specific disadvantaged communities in the country which indicated that in the present era of technological advancement, lack of literacy will continue to affect the life-chances of people in these communities where the rate of literacy remains much lower than the national average. The study investigates into the factors associated with illiteracy, and the attitudes and perceptions of the communities themselves towards literacy programmes and regarding the modalities and strategies of providing literacy. The implications of the study and the final recommendations drawn up in consultation with the policy makers at national and provincial levels in governmental and non-governmental sectors are also discussed in the paper.

  16. Chronic kidney diseases of uncertain etiology (CKDue) in Sri Lanka: geographic distribution and environmental implications.

    PubMed

    Chandrajith, Rohana; Nanayakkara, Shanika; Itai, Kozuyoshi; Aturaliya, T N C; Dissanayake, C B; Abeysekera, Thilak; Harada, Kouji; Watanabe, Takao; Koizumi, Akio

    2011-06-01

    The increase in the number of chronic kidney disease (CKD) patients from the north central region of Sri Lanka has become a environmental health issue of national concern. Unlike in other countries where long-standing diabetes and hypertension are the leading causes of renal diseases, the majority of CKD patients from this part of Sri Lanka do not show any identifiable cause. As the disease is restricted to a remarkably specific geographical terrain, particularly in the north central dry zone of the country, multidisciplinary in-depth research studies are required to identify possible etiologies and risk factors. During this study, population screening in the prevalent region and outside the region, analysis of geoenvironmental and biochemical samples were carried out. Population screening that was carried out using a multistage sampling technique indicated that the point prevalence of CKD with uncertain etiology is about 2-3% among those above 18 years of age. Drinking water collected from high-prevalent and non-endemic regions was analyzed for their trace and ultratrace element contents, including the nephrotoxic heavy metals Cd and U using ICP-MS. The results indicate that the affected regions contain moderate to high levels of fluoride. The Cd contents in drinking water, rice from affected regions and urine from symptomatic and non-symptomatic patients were much lower indicating that Cd is not a contributing factor for CKD with uncertain etiology in Sri Lanka. Although no single geochemical parameter could be clearly and directly related to the CKD etiology on the basis of the elements determined during this study, it is very likely that the unique hydrogeochemistry of the drinking water is closely associated with the incidence of the disease. PMID:20853020

  17. SrI2 scintillator for gamma ray spectroscopy

    NASA Astrophysics Data System (ADS)

    Cherepy, N. J.; Sturm, B. W.; Drury, O. B.; Hurst, T. A.; Sheets, S. A.; Ahle, L. E.; Saw, C. K.; Pearson, M. A.; Payne, S. A.; Burger, A.; Boatner, L. A.; Ramey, J. O.; van Loef, E. V.; Glodo, J.; Hawrami, R.; Higgins, W. M.; Shah, K. S.; Moses, W. W.

    2009-08-01

    We are working to perfect the growth of divalent Eu-doped strontium iodide single crystals and to optimize the design of SrI2(Eu)-based gamma ray spectrometers. SrI2(Eu) offers a light yield in excess of 100,000 photons/MeV and light yield proportionality surpassing that of Ce-doped lanthanum bromide. Thermal and x-ray diffraction analyses of SrI2 and EuI2 indicate an excellent match in melting and crystallographic parameters, and very modest thermal expansion anisotropy. We have demonstrated energy resolution with SrI2(4-6%Eu) of 2.6% at 662 keV and 7.6% at 60 keV with small crystals, while the resolution degrades somewhat for larger sizes. Our experiments suggest that digital techniques may be useful in improving the energy resolution in large crystals impaired by light-trapping, in which scintillation light is re-absorbed and re-emitted in large and/or highly Eu2+ -doped crystals. The light yield proportionality of SrI2(Eu) is found to be superior to that of other known scintillator materials, such as LaBr3(Ce) and NaI(Tl).

  18. Characterisation of cutaneous leishmaniasis in Matara district, southern Sri Lanka: evidence for case clustering.

    PubMed

    Kariyawasam, K K G D U L; Edirisuriya, C S; Senerath, U; Hensmen, D; Siriwardana, H V Y D; Karunaweera, N D

    2015-10-01

    Leishmaniasis is a neglected tropical disease transmitted by Phlebotomus spp. sand flies. Cutaneous leishmaniasis (CL) in Sri Lanka is caused by Leishmania donovani. Transmission patterns are different in Southern and Northern Sri Lanka. Current study examined the prevalence, risk factors and distribution of CL in Matara District, Southern Sri Lanka. Total of 2260 individuals from four District Secretariat divisions (DSDs) were screened by house to house surveys using an interviewer administered questionnaire. The study population had an age range of 1-90 years (median  =  43  ±  17.31), low monthly income ( < 20 000 LKR, 52.8%) and a male to female ratio of 1 : 2. Thirty eight patients were diagnosed by light microscopy, culture and/or PCR with a disease prevalence of 1.68%. Spatial mapping provided evidence for significant case clustering, which tended to be more prominent with proximity to forest areas. The risk factors identified were un-plastered brick walls, absence or low usage of protective measures against insect bites, low income and excessive time (>4 hours/day) spent outdoors. However, exposure of limbs while outdoors, unawareness about the disease, type of occupation, common water source as the mode of water supply and presence of animal shelters within 200 m were not associated with the risk of acquiring the disease. Peri-domestic transmission is likely to contribute to the observed case clustering with all age groups at risk of acquiring the infection. Human behavioural habits coinciding with that of the vector, sand fly are likely to enable host-vector contact promoting its spread. Appropriate vector control measures, improvement of housing conditions, public education regarding preventive measures are required to contain the spread of disease. PMID:26345305

  19. Quantitative and Public Perception of Landslide Risk in Badulla, Sri Lanka

    NASA Astrophysics Data System (ADS)

    Gunasekera, R.; Bandara, R. M. S.; Mallawatantri, A.; Saito, K.

    2009-04-01

    Landslides are often triggered by intense precipitation and are exacerbated by increased urbanisation and human activity. There is a significant risk of large scale landslides in Sri Lanka and when they do occur, they have the potential to cause devastation to property, lives and livelihoods. There are several high landslide risk areas in seven districts (Nuwara Eliya, Badulla, Ratnapura, Kegalle, Kandy, Matale and Kalutara) in Sri Lanka. These are also some of the poorest areas in the country and consequently the recovery process after catastrophic landslides become more problematic. Therefore landslide risk management is an important concern in poverty reduction strategies. We focused on the district of Badulla, Sri Lanka to evaluate the a) quantitative scientific analysis of landslide risk and b) qualitative public perception of landslides in the area. Combining high resolution, hazard and susceptibility data we quantified the risk of landslides in the area. We also evaluated the public perception of landslides in the area using participatory GIS techniques. The evaluation of public perception of landslide risk has been complemented by use of Landscan data. The framework of the methodology for Landscan data is based on using the second order administrative population data from census, each 30 arc-second cell within the administrative units receives a probability coefficient based on slope, proximity to roads and land cover. Provision of this information from these complementary methods to the regional planners help to strengthen the disaster risk reduction options and improving sustainable land use practices through enhanced public participation in the decision making and governance processes.

  20. Chronic kidney disease of uncertain etiology in Sri Lanka: Are leptospirosis and Hantaviral infection likely causes?

    PubMed

    Gamage, Chandika Damesh; Sarathkumara, Yomani Dilukshi

    2016-06-01

    Chronic kidney disease of uncertain etiology (CKDu) has been a severe burden and a public health crisis in Sri Lanka over the past two decades. Many studies have established hypotheses to identify potential risk factors although causative agents, risk factors and etiology of this disease are still uncertain. Several studies have postulated that fungal and bacterial nephrotoxins are a possible etiological factor; however, the precise link between hypothesized risk factors and the pathogenesis of chronic kidney disease has yet to be proven in prior studies. Leptospirosis and Hantavirus infections are important zoonotic diseases that are naturally maintained and transmitted via infected rodent populations and which present similar clinical and epidemiological features. Both infections are known to be a cause of acute kidney damage that can proceed into chronic renal failure. Several studies have reported presence of both infections in Sri Lanka. Therefore, we hypothesized that pathogenic Leptospira or Hantavirus are possible causative agents of acute kidney damage which eventually progresses to chronic kidney disease in Sri Lanka. The proposed hypothesis will be evaluated by means of an observational study design. Past infection will be assessed by a cross-sectional study to detect the presence of IgG antibodies with further confirmatory testing among chronic kidney disease patients and individuals from the community in selected endemic areas compared to low prevalence areas. Identification of possible risk factors for these infections will be followed by a case-control study and causality will be further determined with a cohort study. If the current hypothesis is true, affected communities will be subjected for medical interventions related to the disease for patient management while considering supportive therapies. Furthermore and possibly enhance their preventive and control measures to improve vector control to decrease the risk of infection. PMID:27142134

  1. SRY alone can induce normal male sexual differentiation

    SciTech Connect

    Lopez, M.; Torres, L.; Cervantes, A.

    1995-01-30

    Most individuals with the rare 46,XX male {open_quotes}syndrome{close_quotes} arise due to an unequal interchange between Xp and Yp termini during paternal meiosis. The pattern of Y-sequences in these patients varies considerably, but very few cases have been reported showing only SRY. The phenotype in these patients is also variable ranging from severe impairment of the external genitalia through hypospadias and/or cryptorchidism to occasional normal male phenotype. We report a Mexican 46,XX male patient without genital ambiguities in whom DNA analysis showed the presence of SRY and the absence of ZFY. We conclude that in this case SRY alone was enough for complete male sexual differentiation. 25 refs., 1 fig.

  2. The Asian Tsunami in Sri Lanka: A Personal Experience

    NASA Astrophysics Data System (ADS)

    Chapman, Chris

    2005-01-01

    AGU Fellow Chris Chapman experienced the devastating Asian tsunami firsthand in Sri Lanka. The following is his account, written in the immediate aftermath of the disaster; the footnotes were added later. Chapman is a scientific advisor at Schlumberger Cambridge Research and a specialist in theoretical seismology. At 9:30 A.M. local time (0330 GMT) on Boxing Day, 26 December, my wife, Lillian, and I were eating breakfast at the beachside Triton Hotel1 in Ahungalla, Sri Lanka (about 30 km north of Galle). The previous week we had toured Sri Lanka, ending our trip traveling through Yala National Park and Galle. These were places we hardly knew of before, but now images of them are indelibly imprinted on the world. Of about 150 staying at the Yala Safari Game Lodge, only 11 survived. The center of Galle, a UNESCO World Heritage Site, a sixteenth- to seventeenth-century Portuguese/Dutchfort and port, is essentially gone.

  3. The Twin Research Registry at SRI International.

    PubMed

    Krasnow, Ruth E; Jack, Lisa M; Lessov-Schlaggar, Christina N; Bergen, Andrew W; Swan, Gary E

    2013-02-01

    The Twin Research Registry (TRR) at SRI International is a community-based registry of twins established in 1995 by advertising in local media, mainly on radio stations and in newspapers. As of August 2012, there are 3,120 same- and opposite-sex twins enrolled; 86% are 18 years of age or older (mean age 44.9 years, SD 16.9 years) and 14% less than 18 years of age (mean age 8.9 years, SD 4.5); 67% are female, and 62% are self-reported monozygotic (MZ). More than 1,375 twins have participated in studies over the last 15 years in collaboration with the University of California Medical Center in San Francisco, the University of Texas MD Anderson Cancer Center, and the Stanford University School of Medicine. Each twin completes a registration form with basic demographic information either online at the TRR Web site or during a telephone interview. Contact is maintained with members by means of annual newsletters and birthday cards. The managers of the TRR protect the confidentiality of twin data with established policies; no information is given to other researchers without prior permission from the twins; and all methods and procedures are reviewed by an Institutional Review Board. Phenotypes studied thus far include those related to nicotine metabolism, mutagen sensitivity, pain response before and after administration of an opioid, and a variety of immunological responses to environmental exposures, including second-hand smoke and vaccination for seasonal influenza virus and Varicella zoster virus. Twins in the TRR have participated in studies of complex, clinically relevant phenotypes that would not be feasible to measure in larger samples. PMID:23084148

  4. Cost of malaria control in Sri Lanka.

    PubMed Central

    Konradsen, F.; Steele, P.; Perera, D.; van der Hoek, W.; Amerasinghe, P. H.; Amerasinghe, F. P.

    1999-01-01

    The study provides estimates of the cost of various malaria control measures in an area of North-Central Province of Sri Lanka where the disease is endemic. We assumed that each measure was equally effective. In these terms, impregnating privately purchased bednets with insecticide was estimated to cost Rs 48 (US(40.87) per individual protected per year, less than half the cost of spraying houses with residual insecticides. Larviciding of vector breeding sites and especially the elimination of breeding habitats by flushing streams through seasonal release of water from upstream reservoirs was estimated to be cheaper than other preventive measures (Rs 27 (US$ 0.49) and Rs 13 (US$ 0.24) per individual protected, respectively). Inclusion of both operational and capital costs of treatment indicates that the most cost-effective intervention for the government was a centrally located hospital with a relatively large catchment area (Rs 71 (US$ 1.29) per malaria case treated). Mobile clinics (Rs 153 (US$ 2.78) per malaria case treated) and a village treatment centre (Rs 112 (US$ 2.04)) per malaria case treated) were more expensive options for the government, but were considerably cheaper for households than the traditional hospital facilities. This information can guide health planners and government decision-makers in choosing the most appropriate combination of curative and preventive measures to control malaria. However, the option that is cheapest for the government may not be so for the householders, and further studies are needed to estimate the effectiveness of the various preventive measures. PMID:10327708

  5. A bedside test for methemoglobinemia, Sri Lanka

    PubMed Central

    Dawson, Andrew H; Buckley, Nicholas A

    2016-01-01

    Abstract Problem Propanil is an aniline herbicide that is widely used for rice cultivation, but is also used for self-poisoning. Toxicity from propanil is largely due to methemoglobinemia. In resource-poor settings, the capacity to determine methemoglobin concentration is insufficient and prevents effective case management, which results in increased deaths from propanil poisoning. Approach Blood with a methemoglobin concentration greater than 15% of total haemoglobin levels appears brownish in colour. We introduced a colour reference chart that can be used to semiquantitatively determine methemoglobinemia. Each ward in three rural hospitals received a chart. Ward staff, medical officers and trainee doctors were given a presentation describing the test method and how it should be used with the relevant national treatment guidelines. Local setting In three rural hospitals in Sri Lanka, 401 patients were admitted with a diagnosis of propanil poisoning before the introduction of this test (2003–2007) and 262 patients after it was introduced (2008–2014), 46 of 663 patients died. Relevant changes The chart can be freely produced with any good-quality colour printer. In three rural hospitals, deaths from propanil poisoning fell from 10% of those admitted with this diagnosis in 2003–2007 (38/401) to 3% (8/262) in 2008–2014 and the use of methylene blue increased from 10% (13/136) to 55% (59/107) over this period. Lessons learnt This simple bedside test was associated with increased use of the first line treatment for propanil poisoning and improved survival. In 2011, the test was included in the national guidelines for the management of propanil poisoning. PMID:27516640

  6. Unemployment tables and unemployment-free working life: Sri Lanka.

    PubMed

    Krishnan, P

    1986-01-01

    This paper demonstrates the use of the life table model to depict gross and net tables of unemployment in a country, using Sri Lanka as an example. Age specific data on employment in Sri Lanka are analyzed using the lfe table technic. Unemployment-free working life declined for both males and females between 1963 and 1971, indicating deteriorating employment conditions. This measure shows the employment situation in a country better than the simple rates of unemployment or the conventional working life expectancy. It also shows working life from the point of view of the production of goods and services. PMID:12268132

  7. Surface circulation and upwelling patterns around Sri Lanka

    NASA Astrophysics Data System (ADS)

    de Vos, A.; Pattiaratchi, C. B.; Wijeratne, E. M. S.

    2014-10-01

    Sri Lanka occupies a unique location within the equatorial belt in the northern Indian Ocean, with the Arabian Sea on its western side and the Bay of Bengal on its eastern side, and experiences bi-annually reversing monsoon winds. Aggregations of blue whale (Balaenoptera musculus) have been observed along the southern coast of Sri Lanka during the northeast (NE) monsoon, when satellite imagery indicates lower productivity in the surface waters. This study explored elements of the dynamics of the surface circulation and coastal upwelling in the waters around Sri Lanka using satellite imagery and numerical simulations using the Regional Ocean Modelling System (ROMS). The model was run for 3 years to examine the seasonal and shorter-term (~10 days) variability. The results reproduced correctly the reversing current system, between the Equator and Sri Lanka, in response to the changing wind field: the eastward flowing Southwest Monsoon Current (SMC) during the southwest (SW) monsoon transporting 11.5 Sv (mean over 2010-2012) and the westward flowing Northeast Monsoon Current (NMC) transporting 9.6 Sv during the NE monsoon, respectively. A recirculation feature located to the east of Sri Lanka during the SW monsoon, the Sri Lanka Dome, is shown to result from the interaction between the SMC and the island of Sri Lanka. Along the eastern and western coasts, during both monsoon periods, flow is southward converging along the southern coast. During the SW monsoon, the island deflects the eastward flowing SMC southward, whilst along the eastern coast, the southward flow results from the Sri Lanka Dome recirculation. The major upwelling region, during both monsoon periods, is located along the southern coast, resulting from southward flow converging along the southern coast and subsequent divergence associated with the offshore transport of water. Higher surface chlorophyll concentrations were observed during the SW monsoon. The location of the flow convergence and hence the

  8. Association between underweight and taste sensitivity in middle- to old-aged nursing home residents in Sri Lanka: a cross-sectional study.

    PubMed

    Fuchida, S; Yamamoto, T; Takiguchi, T; Kandaudahewa, G; Yuyama, N; Hirata, Y

    2013-11-01

    Low taste sensitivity may be one factor related to undernutrition, which is a major problem in developing countries. The purpose of this cross-sectional study was to examine the association between underweight, one indicator of undernutrition, and taste sensitivity in middle- to old-aged Sri Lankan nursing home residents. Participants were 946 residents with BMI of <25·0 from 25 nursing homes. Data were obtained on height, weight, taste sensitivity, subjective taste ability, sex, age, ethnicity, number of years in nursing homes, activities of daily living (ADL), frequency of exercise, bowel movements, smoking status, drinking status, current number of chronic diseases, number and kinds of medications used, self-reporting questionnaire 20 (SRQ20), subjective smell ability, number of teeth present, Eichner index and flow rate of saliva. Low sensitivity to bitter taste, being male, old age, low ADL, smoking experience, drinking experience, fewer medications used and no use of medication for hypertension and diabetes were each associated with underweight (P < 0·05). In a multilevel Poisson regression model adjusted for sex, age, ADL, smoking status, drinking status, number of medications used, use of medication for hypertension and diabetes and flow rate of saliva, subjects with low sensitivity (>0·003% quinine hydrochloride dihydrate) to bitter taste had a significant 1·70 times higher prevalence ratio (95% confident interval 1·04-2·80) for underweight compared with those with high sensitivity (0·0001% quinine hydrochloride dihydrate). These results suggest that low taste sensitivity to bitter taste may be one factor related to underweight. PMID:24111976

  9. Understanding the explanatory model of the patient on their medically unexplained symptoms and its implication on treatment development research: a Sri Lanka Study

    PubMed Central

    Sumathipala, Athula; Siribaddana, Sisira; Hewege, Suwin; Sumathipala, Kethaki; Prince, Martin; Mann, Anthony

    2008-01-01

    Background Patients with medically unexplained symptoms (MUS) are often distressed, disabled and dissatisfied with the care they receive. Illness beliefs held by patients have a major influence on the decision to consult, persistence of symptoms and the degree of disability. Illness perception models consist of frameworks to organise information from multiple sources into distinct but interrelated dimensions: identity (the illness label), cause, consequences, emotional representations perceived control and timeline. Our aim was to elicit the illness perceptions of patients with MUS in Sri Lankan primary care to modify and improve a CBT intervention. Method An intervention study was conducted in a hospital primary care clinic in Colombo, Sri Lanka using CBT for MUS. As a part of the baseline assessment, qualitative data was collected using; the Short Explanatory Model Interview (SEMI), from 68 patients (16–65 years) with MUS. We categorised the qualitative data in to key components of the illness perception model, to refine CBT intervention for a subsequent larger trial study. Results The cohort was chronically ill and 87% of the patients were ill for more than six months (range six months to 20 years) with 5 or more symptoms and 6 or more visits over preceding six months. A majority were unable to offer an explanation on identity (59%) or the cause (56%), but in the consequence domain 95% expressed significant illness worries; 37% believed their symptoms indicated moderately serious illness and 58% very serious illness. Reflecting emotional representation, 33% reported fear of death, 20% fear of paralysis, 13% fear of developing cancer and the rest unspecified incurable illness. Consequence and emotional domains were significant determinants of distress and consultations. Their repeated visits were to seek help to alleviate symptoms. Only a minority expected investigations (8.8 %) or diagnosis (8.8%). However, the doctors who had previously treated them allegedly

  10. Morphology and surface topography of the schistosome Bivitellobilharzia nairi from the Asian elephant (Elephas maximus maximus) in Sri Lanka.

    PubMed

    Rajapakse, R P V J; Iwagami, M; Wickramasinghe, S; Walker, S M; Agatsuma, T

    2013-09-01

    Bivitellobilharzia nairi was first recorded from an Indian elephant (Elephas maximus) in Berlin. Infections with this parasite have become increasingly important in E. maximus maximus populations in Sri Lanka. The present work is the first morphological description of this schistosome from Sri Lanka. A number of adult worms were recovered from a dead Asian elephant near the elephant orphanage, Pinnawala, in Sri Lanka. The observed clinical features of the infected elephant included emaciation, subventral oedema and anaemia. Post-mortem results indicated that the liver was enlarged and adult schistosomes were found in the blood vessels of the liver parenchyma. The total number of worms recovered from a portion of the liver was 129,870, which is an average of 22 worms per 100 g of liver. The present study uses both light microscopic and scanning electron microscope (SEM) techniques for the morphological and topographical characterization of this parasite and to permit comparison with other species of schistosomes. Morphologically, these worms correspond very well to the description of B. nairi by Dutt & Srivastava (1955). Moreover, it is clear that B. nairi is a distinctive species easily differentiated from other schistosomes. The SEM study of the tegument of male worms shows that the surface of B. nairi is smoother than in other schistosomes. PMID:22989615

  11. Sry-Independent Overexpression of Sox9 Supports Spermatogenesis and Fertility in the Mouse.

    PubMed

    Ortega, Egle A; Ruthig, Victor A; Ward, Monika A

    2015-12-01

    The Y chromosome gene Sry is responsible for sex determination in mammals and initiates a cascade of events that direct differentiation of bipotential genital ridges toward male-specific fate. Sox9 is an autosomal gene and a primary downstream target of SRY. The activation of Sox9 in the absence of Sry is sufficient for initiation of male-specific sex determination. Sry-to-Sox9 replacement has mostly been studied in the context of sex determination during early embryogenesis. Here, we tested whether Sry-to-Sox9 replacement affects male fertility in adulthood. We examined males with the Y chromosome carrying a deletion removing the endogenous Sry, with testes determination driven either by the Sox9 (XY(Tdym1)Sox9) or the Sry (XY(Tdym1)Sry) transgenes as well as wild-type males (XY). XY(Tdym1)Sox9 males had reduced testes size, altered testes shape and vasculature, and increased incidence of defects in seminiferous epithelium underlying the coelomic blood vessel region when compared to XY(Tdym1)Sry and XY. There were no differences between XY(Tdym1)Sry and XY(Tdym1)Sox9 males in respect to sperm number, motility, morphology, and ability to fertilize oocytes in vitro, but for some parameters, transgenic males were impaired when compared to XY. In fecundity trials, XY(Tdym1)Sry, XY(Tdym1)Sox9, and XY males yielded similar average numbers of pups and litters. Overall, our findings support that males lacking the testis determinant Sry can be fertile and reinforce the notion that Sry does not play a role in mature gonads. Although transgenic Sox9 overexpression in the absence of Sry results in certain testicular abnormalities, it does not translate into fertility impairment. PMID:26536904

  12. An American Montessori Teacher's Experience in Sri Lanka

    ERIC Educational Resources Information Center

    Baker, Irene

    2006-01-01

    What can Montessorians learn from teaching in a war-torn country, and what can they hope to share with others in the process? These questions were much on the author's mind when she went to Sri Lanka in the summer of 2003. This article contains excerpts from e-mails the author sent home, chronicling her experience teaching two high school English…

  13. Can teachers cross continents? Experiences in Sri Lanka

    PubMed Central

    Metcalfe, D. H. H.; Varnam, M. A.

    1981-01-01

    We describe our experience of planning and running a workshop in Sri Lanka to prepare doctors for teaching a postgraduate diploma in general practice. We explore whether British models of education for general practice are applicable in other cultures and put forward a check-list of questions which teachers of general practice who are invited to work abroad should ask themselves. PMID:7328545

  14. Microorganisms in the Coloured Rain of Sri Lanka

    NASA Astrophysics Data System (ADS)

    Samaranayake, Anil; Wickramarathne, K.; Wickramasinghe, N. C.

    2013-02-01

    A variety of pigmented microorganisms have been identified in the red, yellow, blue and black rain that fell over Sri Lanka in December 2012 and January 2013. There is tentative evidence for the presence of similar organisms, including diatoms, in meteorites falling over the same time period. These microorganisms are likely to have served as nuclei for the condensation of rain drops.

  15. An introduction to the mysticism of the sri chakra.

    PubMed

    Krishnakumar, P R

    1992-07-01

    The Sri Chakra is an important device used in the worship of the primordial energy which is the cause for the creation, maintenance and destruction of the cosmos. The author attempts in this article to provide an explanation for the mystical aspects of the celebrated yantra. PMID:22556605

  16. Feeding Hungry Minds: Grassroots Library Services in Sri Lanka.

    ERIC Educational Resources Information Center

    Corea, Ishvari

    1991-01-01

    Describes three specific programs developed in Sri Lanka to provide library services to urban and rural poor people. Providing reading material to children to help raise literacy levels is emphasized, resources required for these extension services are examined, and the responsibility for the administration of the projects is considered. (LRW)

  17. Learning Organization Dimensions of the Sri Lanka Army

    ERIC Educational Resources Information Center

    Dahanayake, Nishada Dhananjaya; Gamlath, Sharmila

    2013-01-01

    Purpose: This study intends to investigate the extent to which the Sri Lanka Army can be described as a learning organization. Design/methodology/approach: The main tool of analysis used was the Dimensions of the Learning Organization Questionnaire (DLOQ) developed by Marsick and Watkins, with the exclusion of the sections on financial and…

  18. The Labour Market Experience of University Graduates in Sri Lanka

    ERIC Educational Resources Information Center

    Chandrasiri, Sunil

    2008-01-01

    Graduate unemployment has been a major socio-politico-economic problem in the small open economy of Sri Lanka for the past 35 years. The nature of the problem, causal factors and policy responses are examined in this paper with a special focus on the role of higher education within a highly competitive and knowledge-based economic environment. The…

  19. The Geodynamic Evolution Of Sri Lanka: A Review

    NASA Astrophysics Data System (ADS)

    Kehelpannala, K.

    2006-12-01

    The high-grade basement of Sri Lanka exposes part of the middle-lower crust and is composed of three distinctly different crustal blocks amalgamated during the assembly of Gondwana in Pan-African. These blocks are known as the Wanni Complex (WC), the Highland Complex (HC) and the Vijayan Complex (VC). The centrally located Palaeoproterozoic HC, which was probably a microcontinent before it became part of Rodinia, is flanked by the Mesoproterozoic-Neoproterozoic WC to the west and by the 1100-1000 Ma old, juvenile VC to the east. The available isotopic and geochemical data suggest that the WC seems to have formed as part of a late Mesoproterozoic-Neoproterozoic Andean-type magmatic arc, possibly at the outer margin of Rodinia, whereas the VC may represents part of a possible 1100-1000 Ma old island arc that possibly extended to the ~1000 Ma Dronning Maud Land-L¨¹tzow Holm Bay belt of east Antarctica. These three different blocks were amalgamated by two separate collisions, possibly related to some arc accretion around Sri Lanka during the assembly of Gondwana at 610-550 Ma. The first collision occurred between the WC arc and the HC microcontinent and was responsible for D2-D4 deformations and the main granulite facies metamorphism in both these units. Shear sense indicators, such as shear band foliations, ¦Ä-type and ¦Ò-type objects, asymmetric and rotated boudins, sheath folds and asymmetric folds, in the high-grade mylonites found along the contact between the WC and the HC indicate that the former was emplaced from NNW on top of the latter. Almost all the ultrahigh temperature assemblages found in Sri Lanka are located along the boundary between the WC and the HC. The second collision was nearly E-W and brought the amalgamated WC/HC unit into contact with the VC island arc and caused D5 structures in both the WC and HC and all the major ductile structures, upper amphibolite facies metamorphism and migmatization in the VC. The arc accretion by these two

  20. Delivery of sry1, but not sry2, to the kidney increases blood pressure and sns indices in normotensive wky rats

    PubMed Central

    Ely, Daniel; Milsted, Amy; Dunphy, Gail; Boehme, Shannon; Dunmire, Jeff; Hart, Mike; Toot, Jonathon; Martins, Almir; Turner, Monte

    2009-01-01

    Background Our laboratory has shown that a locus on the SHR Y chromosome increases blood pressure (BP) in the SHR rat and in WKY rats with the SHR Y chromosome (SHR/y rat). A candidate for this Y chromosome hypertension locus is Sry, a gene that encodes a transcription factor responsible for testes determination. The SHR Y chromosome has six divergent Sry loci. The following study examined if exogenous Sry1 or Sry2 delivered to the kidney would elevate renal tyrosine hydroxylase, renal catecholamines, plasma catecholamines and telemetered BP over a 28 day period. We delivered 50 μg of either the expression construct Sry1/pcDNA 3.1, Sry2/pcDNA 3.1, or control vector into the medulla of the left kidney of normotensive WKY rats by electroporation. Weekly air stress was performed to determine BP responsiveness. Separate groups of animals were tested for renal function and plasma hormone patterns and pharmacological intervention using alpha adrenergic receptor blockade. Pre-surgery baseline and weekly blood samples were taken from Sry1 electroporated and control vector males for plasma renin, aldosterone, and corticosterone. BP was measured by telemetry and tyrosine hydroxylase and catecholamines by HPLC with electrochemical detection. Results In the animals receiving the Sry1 plasmid there were significant increases after 21 days in resting plasma norepinephrine (NE, 27%) and renal tyrosine hydroxylase content (41%, p < .05) compared to controls. BP was higher in animals electroporated with Sry1 (143 mmHg, p < .05) compared to controls (125 mmHg) between 2–4 weeks. Also the pressor response to air stress was significantly elevated in males electroporated with Sry1 (41 mmHg) compared to controls (28 mmHg, p < .001). Sry2 did not elevate BP or SNS indices and further tests were not done. The hormone profiles for plasma renin, aldosterone, and corticosterone between electroporated Sry1 and control vector males showed no significant differences over the 28 day period

  1. Surface circulation and upwelling patterns around Sri Lanka

    NASA Astrophysics Data System (ADS)

    de Vos, A.; Pattiaratchi, C. B.; Wijeratne, E. M. S.

    2013-09-01

    Sri Lanka occupies a unique location within the equatorial belt in the northern Indian Ocean with the Arabian Sea on its western side and the Bay of Bengal on its eastern side. The region is characterised by bi-annually reversing monsoon winds resulting from seasonal differential heating and cooling of the continental land mass and the ocean. This study explored elements of the dynamics of the surface circulation and coastal upwelling in the waters around Sri Lanka using satellite imagery and the Regional Ocean Modelling System (ROMS) configured to the study region and forced with ECMWF interim data. The model was run for 2 yr to examine the seasonal and shorter term (∼10 days) variability. The results confirmed the presence of the reversing current system in response to the changing wind field: the eastward flowing Southwest Monsoon Current (SMC) during the Southwest (SW) monsoon transporting 11.5 Sv and the westward flowing Northeast Monsoon Current (NMC) transporting 9.5 Sv during the Northeast (NE) monsoon, respectively. A recirculation feature located to the east of Sri Lanka during the SW monsoon, the Sri Lanka Dome, is shown to result from the interaction between the SMC and the Island of Sri Lanka. Along the eastern and western coasts, during both monsoon periods, flow is southward converging along the south coast. During the SW monsoon the Island deflects the eastward flowing SMC southward whilst along the east coast the southward flow results from the Sri Lanka Dome recirculation. The major upwelling region, during both monsoon periods, is located along the south coast and is shown to be due to flow convergence and divergence associated with offshore transport of water. Higher surface chlorophyll concentrations were observed during the SW monsoon. The location of the flow convergence and hence the upwelling centre was dependent on the relative strengths of wind driven flow along the east and west coasts: during the SW (NE) monsoon the flow along the

  2. Ethnicity, politics and inequality: post-tsunami humanitarian aid delivery in Ampara District, Sri Lanka.

    PubMed

    Amarasiri de Silva, M W

    2009-04-01

    The provision of humanitarian aid at times of disaster in multi-ethnic community settings may lead to conflict, tension and even the widening of the distance between various ethnic groups. That aid agencies distribute humanitarian aid directly to affected communities, to speed up recovery, may often lead to chaos and the intensification of ethnic sentiments. The new distribution mechanisms introduced for the delivery of tsunami aid in Ampara District, Sri Lanka, did not recognise local networks and the culture of the ethnically mixed community setting. This paper analyses post-tsunami aid distribution in Ampara and shows how such an extemporised effort in an ethnically cognisant context increased ethnic division, inequality and disorder, while marginalising the poor segments of the affected population. It recommends the inclusion of local networks in aid dissemination as a measure for improving ethnic neutrality and social harmony in disaster-hit multi-ethnic communities. PMID:18717702

  3. Situation Reports--Afghanistan, Bahrein, Brazil, Ecuador, Indonesia, Iraq, Morocco, Paraguay, People's Democratic Republic of Yemen, Peru, Qatar, Saudi Arabia, Sri Lanka, St. Christopher/Nevis, Sudan, United Arab Emirates, Yemen Arab Republic.

    ERIC Educational Resources Information Center

    International Planned Parenthood Federation, London (England).

    Data relating to population and family planning in 17 foreign countries are presented in these situation reports. Countries included are Afghanistan, Bahrein, Brazil, Ecuador, Indonesia, Iraq, Morocco, Paraguay, People's Democratic Republic of Yemen, Peru, Qatar, Saudi Arabia, Sri Lanka, St. Christopher/Nevis, Sudan, United Arab Emirates, and…

  4. A deterministic analysis of tsunami hazard and risk for the southwest coast of Sri Lanka

    NASA Astrophysics Data System (ADS)

    Wijetunge, J. J.

    2014-05-01

    This paper describes a multi-scenario, deterministic analysis carried out as a pilot study to evaluate the tsunami hazard and risk distribution in the southwest coast of Sri Lanka. The hazard and risk assessment procedure adopted was also assessed against available field records of the impact of the Indian Ocean tsunami in 2004. An evaluation of numerically simulated nearshore tsunami amplitudes corresponding to ‘maximum-credible' scenarios from different subduction segments in the Indian Ocean surrounding Sri Lanka suggests that a seismic event similar to that generated the tsunami in 2004 can still be considered as the ‘worst-case' scenario for the southwest coast. Furthermore, it appears that formation of edge waves trapped by the primary waves diffracting around the southwest significantly influences the nearshore tsunami wave field and is largely responsible for relatively higher tsunami amplitudes in certain stretches of the coastline under study. The extent of inundation from numerical simulations corresponding to the worst-case scenario shows good overall agreement with the points of maximum penetration of inundation from field measurements in the aftermath of the 2004 tsunami. It can also be seen that the inundation distribution is strongly influenced by onshore topography. The present study indicates that the mean depth of inundation could be utilised as a primary parameter to quantify the spatial distribution of the tsunami hazard. The spatial distribution of the risk of the tsunami hazard to the population and residential buildings computed by employing the standard risk formula shows satisfactory correlation with published statistics of the affected population and the damage to residential property during the tsunami in 2004.

  5. The complete coding region sequence of river buffalo (Bubalus bubalis) SRY gene.

    PubMed

    Parma, Pietro; Feligini, Maria; Greppi, Gianfranco; Enne, Giuseppe

    2004-02-01

    The Y-linked SRY gene is responsible for testis determination in mammals. Mutations in this gene can lead to XY Gonadal Dysgenesis, an abnormal sexual phenotype described in humans, cattle, horses and river buffalo. We report here the complete river buffalo SRY sequence in order to enable the genetic diagnosis of this disease. The SRY sequence was also used to confirm the evolutionary divergence time between cattle and river buffalo 10 million years ago. PMID:15354359

  6. The development of micro-catchments in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Udawattage, U. D. S.

    1985-10-01

    This paper gives an informatory account of the development of micro-catchments in Sri Lanka for irrigation. Information for the paper comes from the experience of detailed investigation and preparation of technical proposals for the improvement of 170 existing micro-scale reservoir schemes in the Puttalam and Kurunegala districts, over a period of three years (January, 1982 through December, 1984), under a World Bank-financed project called "Integrated Rural Development (IRD) Project". Investigations were carried out by a private body called Planning Consultancy, a professional staff comprising a team of eight engineers from the Resources Development Consultants Ltd., Sir Lanka, under a contract with the Ministry of Plan Implementation and under the supervision of the Irrigation Department of Sri Lanka and a World Bank-recommended body called Supervisory Consultancy. The writer is a member of the Planning Consultancy team who personally investigated and designed 30 of these schemes.

  7. Description of Duttaphrynus atukoralei (Anura: Bufonidae) tadpoles from Sri Lanka.

    PubMed

    Bopage, Malaka M; Wewelwala, Krishan; Krvavac, Milivoje; Jovanovic, Olga

    2015-01-01

    Duttaphrynus atukoralei (Bogert & Senanayake, 1966) is a relatively abundant toad known from Southern and Southeastern Sri Lanka. It occurs from sea level up to ~200 m above sea level (IUCN 2014). For almost half a century since its original description there was no information on its life cycle; the only information available is related to its description and distribution (Dutta & Manamendra-Arachchi 1996; Manamendra-Arachchi & Pethiyagoda 2006). PMID:26249461

  8. Determination of the geoid of central highlands in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Prasanna, Herath Mudiyanselage Indika; Tantrigoda, Dhammika Ariyakumara

    2009-06-01

    The available geoid undulations on the WGS84 ellipsoid at over two hundred GPS stations are interpolated using a least-squares surface fitting technique to determine the geoid of the central highlands in Sri Lanka. However, it is not possible to interpolate these points directly to prepare a detailed map of the geoid surface as the geoid separation varies intense due to the rugged local topography making the interpolation inaccurate. The gravity potential and subsequently the undulation of the local geoid due to the topography have been calculated separately using a topographic model and removed from the available geoid undulations. This model was created using information obtained from 1:50 000 digital topographic maps provided by the Survey department of Sri Lanka. The resulting geoid separations were interpolated and three surface polynomials were employed to determine the geoid using the least-squares surface fitting technique. To avoid possible artefacts in regions without observations, an area including central highlands was selected to determine the geoid. Finally, the geoid undulations due to the topography were added back to the Bouguer co-geoid represented by three mathematical surfaces to create a detailed map of the geoid of Sri Lanka. A local positive geoid surface superimposing a large negative regional surface has been obtained and the local maximum value of the geoid undulation is about -92.05 m in the vicinity of Piduruthalagala peak.

  9. CHARACTERISTICS OF PHLEBOTOMINE SANDFLIES IN SELECTED AREAS OF SRI LANKA.

    PubMed

    Senanayake, S A S C; Abeyewicreme, W; Dotson, E M; N D Karunaweera

    2015-11-01

    Cutaneous leishmaniasis (CL) is an endemic disease in Sri Lanka. Studies on vector aspects, although important for better understanding of disease transmission dynamics, are still limited. The present study describes the species distribution and behavioral patterns of sandflies within selected disease-prevalent zones in the country. Adult sandflies were collected from several field sites over a two-year duration in Sri Lanka using cattle-baited net traps, CDC light traps and manual methods. Species identification was performed using standard keys. Leishmania donovani and source of blood meal in blood-fed female sandflies DNA were identified using PCR-based methods. Aggregation period of adult sandflies during overnight collections was also noted. The collected sandflies were identified as Phlebotomus argentipes glaucus (previously known as morphospecies A) and a non-vector species, Sergentomyia zeylanica. Presence of L. donovani DNA was found in 2/634 female sandflies. The parasite ITS1 region of SSU rDNA had 99% sequence similarity with L. donovani from Bangladesh and India. The peak aggregation period of sandflies within cattle-traps was between 8:00 PM to 11:00 PM, indicating that vector control strategies could be conducted during this time period. As Sergentomyia zeylanica is likely to be merely a biting nuisance and showed more of an anthropophilic behavior, whereas the probable vector of CL in Sri Lanka (P. argentipes glaucus) demonstrated zoophilic behavior, has implications for the planning of future vector control strategies. PMID:26867357

  10. Using Climate Information for Disaster Risk Identification in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Zubair, L.

    2004-12-01

    We have engaged in a concerted attempt to undertake research and apply earth science information for development in Sri Lanka, with a focus on climate sciences. Here, we provide details of an ongoing attempt to harness science for disaster identification as a prelude to informed disaster management. Natural disasters not only result in death and destruction but also undermine decades of development gains as highlighted by recent examples from Sri Lanka. First, in May 2003, flooding and landslides in the South-West led to 260 deaths, damage to 120,000 homes and destruction of schools, infrastructure and agricultural land. Second, on December 26, 2000, a cyclone in the North-Central region left 8 dead, 55,000 displaced, with severe damage to fishing, agriculture, infrastructure and cultural sites. Third, an extended island-wide drought in 2001 and 2002 resulted in a 2% drop in GDP. In the aftermath of these disasters, improved disaster management has been deemed to be urgent by the Government of Sri Lanka. In the past the primary policy response to disasters was to provide emergency relief. It is increasingly recognized that appropriate disaster risk management, including risk assessment, preventive measures to reduce losses and improved preparedness, can help reduce death, destruction and socio-economic disruption. The overwhelming majority of hazards in Sri Lanka - droughts, floods, cyclones and landslides -have hydro-meteorological antecedents. Little systematic advantage has, however, been taken of hydro-meteorological information and advances in climate prediction for disaster management. Disaster risks are created by the interaction between hazard events and vulnerabilities of communities, infrastructure and economically important activities. A comprehensive disaster risk management system encompasses risk identification, risk reduction and risk transfer. We undertook an identification of risks for Sri Lanka at fine scale with the support of the Global Disaster

  11. Delineation of Tsunami Risk Zones for Sri Lanka

    NASA Astrophysics Data System (ADS)

    Wijetunge, J. J.

    2008-12-01

    The coastal belts of several Indian Ocean countries including Indonesia, Sri Lanka, India and Thailand suffered massive loss of life and damage to property due to the tsunami unleashed by the great earthquake of moment magnitude 9.1-9.3 in the Andaman-Sunda subduction zone on December 26, 2004. In Sri Lanka, 13 of the 14 administrative districts lying along the coastal belt were affected: the death toll was over 35,000 with 20,000 injured and about 100,000 dwellings and other buildings either completely or partially damaged leaving half a million people homeless and causing massive disruption to livelihoods. However, it was clear in the immediate aftermath of the tsunami that the degree of damage along the coastal belt of Sri Lanka was not uniform: some areas suffered more damage, some less, and in certain other areas, often not far away, there was no damage at all. This suggests that the level of risk for coastal communities from future events of tsunami exhibits considerable variation even along a short stretch of the shoreline. The high cost and the scarcity of coastal lands in many areas demand an accurate assessment of the tsunami risk rather than arbitrary conservative zonation. Moreover, information relating to the spatial distribution of tsunami risk is essential in formulating post-tsunami coastal land use plans as well as in planning of evacuation of people during tsunami warnings. However, neither comprehensive probabilistic assessments of the tsunami hazard nor detailed information pertaining to the vulnerability of coastal communities are available at present for the coastal zone of Sri Lanka. Consequently, the methodology adopted in the present paper is to use field observations and numerical simulations of the December 2004 tsunami, which may be considered a worst-case scenario, in order to obtain the variation along the coastline of three parameters that quantify the tsunami impact. These three parameters are the tsunami height, the horizontal

  12. State-society relations and electricity infrastructure: Negotiating national energy security in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Caron, Cynthia Marie

    In this dissertation, I use electricity production and distribution and grid expansion as a lens to view and understand state-society relations. After discussing how electricity has resource-like characteristics and institutional characteristics as a field of organization, I examine how groups in society interact with state officials and their corresponding institutions over electricity production and distribution and the pursuit of national energy security. Taking Sri Lanka as the focus of my inquiry, I conducted a qualitative research project to: (1) identify how class, ethnicity, and locality (urban or rural location) are constitutive of and constituted by electricity-infrastructure development and grid expansion initiatives; (2) identify how grid expansion contributes to processes of social inclusion and exclusion by reconstituting on-grid and off-grid populations, and; (3) determine the effects of privatization and environmental regulation on relationships between the state and groups in society. The methodological approaches include analyses of open-ended interviews, participant observation, surveys of government documents, and speeches and sermons delivered at protests against power-plant sitings to examine how groups in society engage the state as a social force. The study finds that privatization occurring in Sri Lanka's energy sector may have the effect of maintaining exclusion from electricity access rather than increasing access to electricity as the neoliberal paradigm asserts. Environmental regulations enable groups in society to include their concerns into the development process and to challenge state decision making that have been made on their behalf by the Ceylon Electricity Board (CEB). The research suggests that class, ethnic, and rural-urban relations are constitutive factors in electricity production and distribution that complement foci on the technical and economic dimensions of electricity-infrastructure planning.

  13. Road traffic crashes, injury and fatality trends in Sri Lanka: 1938–2013

    PubMed Central

    Dharmaratne, Samath D; Jayatilleke, Achini C

    2015-01-01

    Abstract Objective To analyse trends in road traffic crashes, injuries and fatalities over 75 years in Sri Lanka. Methods Data on road traffic crashes, injuries and fatalities between 1938 and 2013 were obtained from the Police Statistics Unit. Rates per 100 000 population were calculated and trends were analysed using joinpoint regression analysis. Findings Road traffic crashes and injuries rose substantially between 1938 and 2013: annual crashes increased from 61.2 to 183.6 per 100 000 people; injuries, from 35.1 to 98.6 per 100 000; and fatalities, from 3.0 to 10.8 per 100 000 people per year. Joinpoint analysis showed large fluctuations in crashes and injuries over time but the fatalities rose almost continuously. These fluctuations paralleled the country’s political and economic development. In some years, better traffic law enforcement and improved public transportation may have been associated with reduced crashes and injuries, whereas rapid growth in vehicle numbers, especially two- and three-wheeled vehicles, may have contributed to increased crashes and injuries. In addition, insurance policies that did not require a police report to claim may have led to underreporting of crashes and allowed drivers to avoid prosecution. Conclusion Fluctuations over time in road traffic crashes and injuries in Sri Lanka are associated with changes in political, economic and traffic policy. There is potential for reducing road traffic crashes and injuries through better traffic law enforcement, restrictions on the importation of two- and three-wheeled vehicles and policies to improve road safety and prevent underreporting of crashes. PMID:26478628

  14. From pesticides to medicinal drugs: time series analyses of methods of self-harm in Sri Lanka

    PubMed Central

    Senanayake, SM; Dias, P; Hanwella, R

    2012-01-01

    Abstract Objective To explore if recent changes in methods of self-harm in Sri Lanka could explain the decline in the incidence of suicide. Methods Time series analyses of suicide rates and hospitalization due to different types of poisoning were carried out. Findings Between 1996 and 2008 the annual incidence of hospital admission resulting from poisoning by medicinal or biological substances increased exponentially, from 48.2 to 115.4 admissions per 100 000 population. Over the same period, annual admissions resulting from poisoning with pesticides decreased from 105.1 to 88.9 per 100 000. The annual incidence of suicide decreased exponentially, from a peak of 47.0 per 100 000 in 1995 to 19.6 per 100 000 in 2009. Poisoning accounted for 37.4 suicides per 100 000 population in 1995 but only 11.2 suicides per 100 000 in 2009. The case fatality rate for pesticide poisoning decreased linearly, from 11.0 deaths per 100 cases admitted to hospital in 1997 to 5.1 per 100 in 2008. Conclusion Since the mid 1990s, a trend away from the misuse of pesticides (despite no reduction in pesticide availability) and towards increased use of medicinal and other substances has been seen in Sri Lanka among those seeking self-harm. These trends and a reduction in mortality among those suffering pesticide poisoning have resulted in an overall reduction in the national incidence of accomplished suicide. PMID:22271963

  15. Cultural Revitalization, Participatory Nonformal Education, and Village Development in Sri Lanka: The Sarvodaya Shramadana Movement.

    ERIC Educational Resources Information Center

    Colletta, N.J.; And Others

    1982-01-01

    Reports results of a study of the Sarvodaya Shramadana Movement in Sri Lanka. Sarvodaya is a nonprofit, nongovernment community education-cum-development movement working in nearly 3,000 villages in Sri Lanka. "Sarvodaya" means universal awakening and "Shramadana" means sharing of one's time, energy, and thought for the good of all. (Author)

  16. Losing Ground: A Critical Analysis of Teachers' Agency for Peacebuilding Education in Sri Lanka

    ERIC Educational Resources Information Center

    Lopes Cardozo, Mieke T. A.; Hoeks, Celine C. M. Q.

    2015-01-01

    This paper aims to explore the "agency" of teachers for peacebuilding education in Sri Lanka through a critical multiscalar analysis of the interplay between "context"--education policies and governance--and "agent"--teachers as strategic political actors. It draws on two studies conducted in Sri Lanka in 2006 and…

  17. Completed Suicide among Sinhalese in Sri Lanka: A Psychological Autopsy Study

    ERIC Educational Resources Information Center

    Samaraweera, Sudath; Sumathipala, Athula; Siribaddana, Sisira; Sivayogan, S.; Bhugra, Dinesh

    2008-01-01

    Sri Lanka has the one of highest rates of suicide. Important factors associated with suicide were determined via the psychological autopsy approach (which had not been carried out previously in Sri Lanka). Over a 3-month period, in a catchment area, 31 suicides among Sinhalese were identified and 27 were investigated. Males were more likely to…

  18. The Role of UK Qualification Suppliers in Sri Lanka and Zimbabwe: A Comparative Evaluation

    ERIC Educational Resources Information Center

    Evans, J.; Little, A. W.

    2007-01-01

    This paper is based on research on the role of UK qualifications suppliers in providing qualifications and accreditation in Sri Lanka and Zimbabwe in the context of rather different engagements with liberalisation, structural adjustment and globalisation. Sri Lanka's economic liberalisation and growth since the late 1970s has had a "de facto"…

  19. Sri Dattatreya's 24 Gurus: Learning from the World in Hindu Tradition

    ERIC Educational Resources Information Center

    Haigh, Martin

    2007-01-01

    Sri Dattatreya, who Lord Krishna quotes in "The Uddhava Gita", has been evoked as a guru for environmental education. Sri Dattatreya gained enlightenment by observing the world, which provided Him with 24 instructors. These taught Him the futility of mundane attachments, the benefits of contemplation and forebearance, and a path towards the…

  20. Returns to Education in Sri Lanka: A Pseudo-Panel Approach

    ERIC Educational Resources Information Center

    Himaz, Rozana; Aturupane, Harsha

    2016-01-01

    This study employs a pseudo-panel approach to estimate the returns to education among income earners in Sri Lanka. Pseudo-panel data are constructed from nine repeated cross sections of Sri Lanka's Labor Force Survey data from 1997 to 2008, for workers born during 1953-1974. The results show that for males, one extra year of education increases…

  1. Language Policy, Ethnic Tensions and Linguistic Rights in Post War Sri Lanka

    ERIC Educational Resources Information Center

    Herath, Sreemali

    2015-01-01

    As in many former colonies, language policy and planning in Sri Lanka has been largely shaped by and continues to be overshadowed by its history of colonial rule. Sri Lanka experienced colonization under three different western powers for over four centuries. This situation was further muddied by the three-decades long ethnic-based civil war which…

  2. The Changing Times: General Education and the Vocational Training System in Sri Lanka

    ERIC Educational Resources Information Center

    Sedere, Upali M.

    2010-01-01

    Sri Lanka is widening its scope for vocational education sub-sector. The emerging global trends and the aspirations of the emerging Sri Lanka after defeating terrorism demands the preparation of the graduating youth at different stages of the education system for employment. Vocational education faces many challenges. Though there are…

  3. Development and Initial Validation of the Satisfaction and Recovery Index (SRI) for Measurement of Recovery from Musculoskeletal Trauma

    PubMed Central

    Walton, David M; MacDermid, Joy C; Pulickal, Mathew; Rollack, Amber; Veitch, Jennifer

    2014-01-01

    Background: There is a need for a generic patient-reported outcome (PRO) that is patient-centric and offers sound properties for measuring the process and state of recovery from musculoskeletal trauma. This study describes the construction and initial validation of a new tool for this purpose. Methods: A prototype tool was constructed through input of academic and clinical experts and patient representatives. After evaluation of individual items, a 9-item Satisfaction and Recovery Index (SRI) was subject to psychometric evaluation drawn from classical test theory. Subjects were recruited through online and clinical populations, from those reporting pain or disability from musculoskeletal trauma. The full sample (N = 129) completed the prototype tool and a corresponding region-specific disability measure. A subsample (N = 46) also completed the Short-Form 12 version 2 (SF12vs). Of that, a second subsample (N = 29) repeated all measures 3 months later. Results: A single factor ‘health-related satisfaction’ was extracted that explained 71.1% of scale variance, Cronbach’s alpha = 0.95. A priori hypotheses for cross-sectional correlations with region-specific disability measures and the generic Short-form 12 component scores were supported. The SRI tool was equally responsive to change, and able to discriminate between recovered/non-recovered subjects, at a level similar to that of the region-specific measures and generally better than the SF-12 subscales. Conclusion: The new SRI tool, as a measure of health-related satisfaction, shows promise in this initial evaluation of its properties. It is generic, patient-centered, and shows overall measurement properties similar to that of region-specific measures while allowing the potential benefit of comparison between clinical conditions. Despite early promising results, additional properties need to be explored before the tool can be endorsed for routine clinical use. PMID:25320652

  4. Sex determination in mammals--before and after the evolution of SRY.

    PubMed

    Wallis, M C; Waters, P D; Graves, J A M

    2008-10-01

    Therian mammals (marsupials and placentals) have an XX female: XY male sex chromosome system, which is homologous to autosomes in other vertebrates. The testis-determining gene, SRY, is conserved on the Y throughout therians, but is absent in other vertebrates, suggesting that the mammal system evolved about 310 million years ago (MYA). However, recent work on the basal monotreme mammals has completely changed our conception of how and when this change occurred. Platypus and echidna lack SRY, and the therian X and Y are represented by autosomes, implying that SRY evolved in therians after their divergence from monotremes only 166 MYA. Clues to the ancestral mechanism usurped by SRY in therians are provided by the monotremes, whose sex chromosomes are homologous to the ZW of birds. This suggests that the therian X and Y, and the SRY gene, evolved from an ancient bird-like sex chromosome system which predates the divergence of mammals and reptiles 310 MYA. PMID:18581056

  5. Validation of the Suicide Resilience Inventory-25 (SRI-25) in adolescent psychiatric inpatient samples.

    PubMed

    Gutierrez, Peter M; Freedenthal, Stacey; Wong, Jane L; Osman, Augustine; Norizuki, Tamami

    2012-01-01

    Resilience has been associated with a markedly decreased chance for risky behaviors following a trauma or other negative life event. This study examined the factor structure and psychometric properties of a self-report measure of resilience, the Suicide Resilience Inventory-25 (SRI-25; Osman et al., 2004 ), among psychiatric inpatient adolescents. In Study 1, we conducted confirmatory factor analysis to provide additional empirical support for the structure and invariance of the 3-factor model of the SRI-25 in youth samples, ages 14 to 17 years (N = 152 boys, 220 girls). Scale reliability analyses provided good evidence for internal consistency reliability of scores on the SRI-25 total and scales. In Study 2 (N = 30 boys, 40 girls), we presented data in support for the concurrent validity (i.e., known groups) of scores on the SRI-25. Additionally, we identified potential correlates for the SRI-25 total scale scores. PMID:22176266

  6. Occurrence of toxigenic cyanobacterial blooms in freshwaters of Sri Lanka.

    PubMed

    Jayatissa, L P; Silva, E I L; McElhiney, J; Lawton, L A

    2006-03-01

    A previous pioneering study of freshwater bodies in Sri Lanka revealed the presence of toxic cyanobacteria in three out of four water bodies tested. It was therefore important to perform a more detailed investigation into the presence of cyanobacteria and their toxins throughout Sri Lanka. The country has a long history of well-planned water management with the agricultural economy and drinking water supply still dependent on thousands of man-made tanks. Seventeen reservoirs from different user categories and different climatic zones were selected to study variations in phytoplankton communities with relation to major nutrients, with particular emphasis on cyanobacteria. The study was carried out during a two-year period and heavy growths or blooms of cyanobacteria observed during the study period were tested for microcystins. The results clearly categorised the 17 reservoirs into four groups parallel to the classification based on the user categories of water bodies. Biomass of total phytoplankton, the abundance of cyanobacteria, the dominance of Microcystis spp. and concentration of nitrate (N) and total phosphorous (P) were the lowest in drinking water bodies and the highest in aesthetic water bodies. Irrigation water bodies showed the second lowest values for phytoplankton biomass, and concentration of N and P, while hydropower reservoirs showed the second highest values for the same parameters. The fraction of cyanobacteria in irrigation waters was higher than that in hydropower reservoirs, but surprisingly the dominance of Microcystis spp. was reversed. Possible reasons for these variations are discussed. More than half of the bloom material tested contained microcystins up to 81microgl(-1). Our findings indicate the potential for high-risk situations due to toxigenic cyanobacterial blooms in susceptible freshwaters of Sri Lanka. PMID:16464697

  7. Determinants of leptospirosis in Sri Lanka: Study Protocol

    PubMed Central

    2010-01-01

    Background Leptospirosis is becoming a major public health threat in Sri Lanka as well as in other countries. We designed a case control study to determine the factors associated with local transmission of leptospirosis in Sri Lanka, in order to identify major modifiable determinants of leptospirosis. The purpose of this paper is to describe the study protocol in detail prior to the publishing of the study results, so that the readership will be able to understand and interpret the study results effectively. Methods A hospital based partially matched case control design is proposed. The study will be conducted in three selected leptospirosis endemic districts in central Sri Lanka. Case selection will include screening all acute fever patients admitted to selected wards to select probable cases of leptospirosis and case confirmation using an array of standard laboratory criteria. Age and sex matched group of acute fever patients with other confirmed diagnosis will be used as controls. Case to control ratio will be 1:2. A minimum sample of 144 cases is required to detect 20% exposure with 95% two sided confidence level and 80% power. A pre tested interviewer administered structured questionnaire will be used to collect data from participants. Variables included in the proposed study will be evaluated using conceptual hierarch of variables in three levels; Exposure variables as proximal; reservoir and environmental variables as intermediate; socio-demographic variables as distal. This conceptual hierarch hypothesised that the distal and intermediate variables are mediated through the proximal variables but not directly. A logistic regression model will be used to analyse the probable determinants of leptospirosis. This model will evaluate the effect of same level and upper level variables on the outcome leptospirosis, using three blocks. Discussion The present national control programme of leptospirosis is hampered by lack of baseline data on leptospirosis disease

  8. Spatial and temporal variations of thunderstorm activities over Sri Lanka

    NASA Astrophysics Data System (ADS)

    Sonnadara, Upul

    2016-05-01

    Spatial and temporal variation of frequencies of thunderstorms over Sri Lanka using thunder day data is presented. A thunder day is simply a calendar day in which thunder is heard at least once at a given location. Two sets of data were collected and analyzed: annual totals for 10 climatological stations for a period of 50 years and monthly totals for 20 climatological stations for a period of 20 years. The average annual thunder days over Sri Lanka was found to be 76. Among the climatological stations considered, a high number of annual thunder days was recorded in Ratnapura (150 days/year), followed by Colombo (108 days/year) and Bandarawela (106 days/year). It appears that there are no widespread long-term increasing or decreasing trends in thunderstorm frequencies. However, Colombo, the capital of Sri Lanka which has over two million people shows an increasing trend of 0.8 thunder days per year. Although there is a high variability between stations reporting the number of thunder days, the overall pattern within a year is clear. Thunderstorm frequencies are high during two periods: March-May and September-November, which coincide with the first inter-monsoon and second inter-monsoon periods. Compared to the dry zone, the wet zone, especially the southwestern region, has high thunderstorm activity. There is a clear spatial difference in thunderstorm activities during the southwest and northeast monsoon seasons. During both these seasons, enhanced thunderstorm activities are reported on the leeward side of the mountain range. A slight reduction in the thunderstorm activities was found in the high elevation areas of the hill country compared to the surrounding areas. A lightning ground flash density map derived using annual thunder days is also presented.

  9. Environmentally Induced Epigenetic Transgenerational Inheritance of Altered SRY Genomic Binding During Gonadal Sex Determination

    PubMed Central

    Skinner, Michael K.; Bhandari, Ramji K.; Haque, M. Muksitul; Nilsson, Eric E.

    2016-01-01

    A critical transcription factor required for mammalian male sex determination is SRY (sex determining region on the Y chromosome). The expression of SRY in precursor Sertoli cells is one of the initial events in testis development. The current study was designed to determine the impact of environmentally induced epigenetic transgenerational inheritance on SRY binding during gonadal sex determination in the male. The agricultural fungicide vinclozolin and vehicle control (DMSO) exposed gestating females (F0 generation) during gonadal sex determination promoted the transgenerational inheritance of differential DNA methylation in sperm of the F3 generation (great grand-offspring). The fetal gonads in F3 generation males were used to identify potential alterations in SRY binding sites in the developing Sertoli cells. Chromatin immunoprecipitation with an SRY antibody followed by genome-wide promoter tiling array (ChIP-Chip) was used to identify alterations in SRY binding. A total of 81 adjacent oligonucleotide sites and 173 single oligo SRY binding sites were identified to be altered transgenerationally in the Sertoli cell vinclozolin lineage F3 generation males. Observations demonstrate the majority of the previously identified normal SRY binding sites were not altered and the altered SRY binding sites were novel and new additional sites. The chromosomal locations, gene associations and potentially modified cellular pathways were investigated. In summary, environmentally induced epigenetic transgenerational inheritance of germline epimutations appears to alter the cellular differentiation and development of the precursor Sertoli cell SRY binding during gonadal sex determination that influence the developmental origins of adult onset testis disease. PMID:27175298

  10. A week of SRI 2003 in San Francisco

    SciTech Connect

    Robinson, Art

    2003-09-29

    The Eighth International Conference on Synchrotron Radiation (SRI 2003) ended its August 25-28 run at the Yerba Buena Center for the Arts in San Francisco with almost as many in attendance as at the beginning. The steady attendance was surely a tribute to the quality of the program and the excitement it generated among the more than 700 registrants who gathered for four days of plenary talks, parallel sessions, and posters, as well as facility tours of the ALS and SSRL on August 29.

  11. Ayurveda, malaria and the indigenous herbal tradition in Sri Lanka.

    PubMed

    Silva, K T

    1991-01-01

    Using key informants and available records, the way in which inhabitants of purana villages in Nuwarakalaviya, Sri Lanka coped with malaria during the pre-DDT era is examined. This study found that the Nuwarakalaviya peasants responded to endemic malaria through a localized herbal tradition, which was to some extent independent of the scholarly ayurveda system common to the whole of South Asia. The relevant herbal tradition, consisting of a combination of antiparasite and antivector strategies using locally available natural resources, represented an effective adaptation to the local ecosystem. PMID:1887278

  12. Indian Ocean, Maldive Islands, India, and Sri Lanka

    NASA Technical Reports Server (NTRS)

    1990-01-01

    This scene shows a fantastic view of the Indian Ocean with oblique views of the southern portion of India, Palk Strait and Sri Lanka (1.5N, 77.5E). The bottom portion of the photo shows the complete chain of the Maldive Islands. This is a rare detailed view of the atolls that form the Maldives. The dusty atmosphere over India is clearly visible as it extends towards the Bay of Bengal but the atmosphere over the Maldives appears to be clear at this time.

  13. Integrated approach for coastal hazards and risks in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Garcin, M.; Desprats, J. F.; Fontaine, M.; Pedreros, R.; Attanayake, N.; Fernando, S.; Siriwardana, C. H. E. R.; de Silva, U.; Poisson, B.

    2008-06-01

    The devastating impact of the tsunami of 26 December 2004 on the shores of the Indian Ocean recalled the importance of knowledge and the taking into account of coastal hazards. Sri Lanka was one of the countries most affected by this tsunami (e.g. 30 000 dead, 1 million people homeless and 70% of the fishing fleet destroyed). Following this tsunami, as part of the French post-tsunami aid, a project to establish a Geographical Information System (GIS) on coastal hazards and risks was funded. This project aims to define, at a pilot site, a methodology for multiple coastal hazards assessment that might be useful for the post-tsunami reconstruction and for development planning. This methodology could be applied to the whole coastline of Sri Lanka. The multi-hazard approach deals with very different coastal processes in terms of dynamics as well as in terms of return period. The first elements of this study are presented here. We used a set of tools integrating a GIS, numerical simulations and risk scenario modelling. While this action occurred in response to the crisis caused by the tsunami, it was decided to integrate other coastal hazards into the study. Although less dramatic than the tsunami these remain responsible for loss of life and damage. Furthermore, the establishment of such a system could not ignore the longer-term effects of climate change on coastal hazards in Sri Lanka. This GIS integrates the physical and demographic data available in Sri Lanka that is useful for assessing the coastal hazards and risks. In addition, these data have been used in numerical modelling of the waves generated during periods of monsoon as well as for the December 2004 tsunami. Risk scenarios have also been assessed for test areas and validated by field data acquired during the project. The results obtained from the models can be further integrated into the GIS and contribute to its enrichment and to help in better assessment and mitigation of these risks. The coastal

  14. Impacts of management alternatives on rice yield and nitrogen losses to the environment: A case study in rural Sri Lanka.

    PubMed

    Stone, Elizabeth C; Hornberger, George M

    2016-01-15

    Maintaining crop yields is vital as populations increase, but environmental degradation resulting from cultivation must be prevented. In particular, freshwater resources are at risk of nitrate leaching from superfluous fertilization. This research explores the tradeoffs between maximizing yield and limiting environmental impacts of rice production in Sri Lanka. The DeNitrification-DeComposition (DNDC) model was used to examine how various combinations of fertilization and irrigation management affect yield, nitrous oxide (N2O) emissions, and nitrogen (N) leaching in paddy systems under climate and soil conditions in the dry zone of Sri Lanka from 1991 to 2010. Simulated fertilizer application rates ranged from zero to 2700 kgN/ha and simulated irrigation schemes were continuously flooded, marginally flooded, and rain-fed. Increasing fertilizer levels from zero to 300 kgN/ha per year increased yield but application of fertilizer beyond that amount ceased to affect yield for any of the three irrigation schemes. The combination of management options for obtaining the maximum grain yield, near 9000 kgC/ha, with the greatest amount of N uptake and relatively low nitrate leaching was using 225 kgN/ha under a continuously flooded regime. This research explores how cultivation in rice-growing regions in south Asia affects the environment and the N cycle, and demonstrates how informed management of these systems can reduce external inputs of N fertilizer without impacting yield. PMID:26519587

  15. Sexual dimorphism in digital dermatoglyphic traits among Sinhalese people in Sri Lanka

    PubMed Central

    2013-01-01

    Background The purpose of this study was to evaluate gender-wise diversity of digital dermatoglyphic traits in a sample of Sinhalese people in Sri Lanka. Findings Four thousand and thirty-four digital prints of 434 Sinhalese individuals (217 males and 217 females) were examined for their digital dermatoglyphic pattern distribution. The mean age for the entire group was 23.66 years (standard deviation = 4.93 years). The loop pattern is observed more frequently (n = 2,592, 59.72%) compared to whorl (n = 1,542, 35.53%) and arch (n = 206, 4.75%) in the Sinhalese population. Females (n = 1,274, 58.71%) have a more ulnar loop pattern than males (n = 1,231, 56.73%). The plain whorl pattern is observed more frequently in males (n = 560, 25.81%) compared to females (n = 514, 23.69%).The double loop pattern is observed more frequently on the right and left thumb (digit 1) of both males and females. Pattern intensity index, Dankmeijer index and Furuhata index are higher in males. Conclusions Ulnar loop is the most frequently occurring digital dermatoglyphic pattern among the Sinhalese. All pattern indices are higher in males. To some extent, dermatoglyphic patterns of Sinhalese are similar to North Indians and other Caucasoid populations. Further studies with larger sample sizes are recommended to confirm our findings. PMID:24377367

  16. Development in a 46 XX boy with positive SRY gene.

    PubMed

    Rego, A; Margarit, E; Estivill, X; Regal, M; García-Mayor, R V

    1996-01-01

    We present the case of an 11 year-old boy, who asked for medical attention due to obesity and assumed underdeveloped external genitalia. He did not have genital anomalies, penile length was 5.3 cm, testicular volume 2 ml and pubic hair Tanner stage 1. His bone age was normal for chronological age. Endocrinological study showed normal results for his age. Karyotype revealed a 46 XX pattern. MRI of external genitalia showed bilateral scrotal testes which were normal in diameter for his age. The check of his historical growth chart and follow-up revealed normal growth with spontaneous pubertal development. However, hormonal studies showed progressive increase of FSH levels, indicative of failure of germinal epithelium. The presence of Y sequences, including SRY gene, was demonstrated by PCR. Our observation is in agreement with the view that 46 XX male subjects diagnosed at peripubertal age with the SRY gene in the genome have a good prognosis regarding growth and development, but the principal problem of these patients is infertility. PMID:9004179

  17. Intimate partner violence in Sri Lanka: a scoping review.

    PubMed

    Guruge, S; Jayasuriya-Illesinghe, V; Gunawardena, N; Perera, J

    2015-12-01

    South Asia is considered to have a high prevalence of intimate partner violence (IPV) against women. Therefore the World Health Organisation has called for context-specific information about IPV from different regions. A scoping review of published and gray literature over the last 35 years was conducted using Arksey and O'Malley's framework. Reported prevalence of IPV in Sri Lanka ranged from 20-72%, with recent reports of rates ranging from 25- 35%. Most research about IPV has been conducted in a few provinces and is based on the experience of legally married women. Individual, family, and societal risk factors for IPV have been studied, but their complex relationships have not been comprehensively investigated. Health consequences of IPV have been reported, with particular attention to physical health, but women are likely to underreport sexual violence. Women seek support mainly from informal networks, with only a few visiting agencies to obtain help. Little research has focused on health sector responses to IPV and their effectiveness. More research is needed on how to challenge gendered perceptions about IPV. Researchers should capture the experience of women in dating/cohabiting relationships and women in vulnerable sectors (post-conflict areas and rural areas), and assess how to effectively provide services to them. A critical evaluation of existing services and programmes is also needed to advance evidence informed programme and policy changes in Sri Lanka. PMID:26778392

  18. Internet-based media coverage on dengue in Sri Lanka between 2007 and 2015

    PubMed Central

    Wilder-Smith, Annelies; Cohn, Emily; Lloyd, David C.; Tozan, Yesim; Brownstein, John S.

    2016-01-01

    Background Internet-based media coverage to explore the extent of awareness of a disease and perceived severity of an outbreak at a national level can be used for early outbreak detection. Dengue has emerged as a major public health problem in Sri Lanka since 2009. Objective To compare Internet references to dengue in Sri Lana with references to other diseases (malaria and influenza) in Sri Lanka and to compare Internet references to dengue in Sri Lanka with notified cases of dengue in Sri Lanka. Design We examined Internet-based news media articles on dengue queried from HealthMap for Sri Lanka, for the period January 2007 to November 2015. For comparative purposes, we compared hits on dengue with hits on influenza and malaria. Results There were 565 hits on dengue between 2007 and 2015, with a rapid rise in 2009 and followed by a rising trend ever since. These hits were highly correlated with the national epidemiological trend of dengue. The volume of digital media coverage of dengue was much higher than of influenza and malaria. Conclusions Dengue in Sri Lanka is receiving increasing media attention. Our findings underpin previous claims that digital media reports reflect national epidemiological trends, both in annual trends and inter-annual seasonal variation, thus acting as proxy biosurveillance to provide early warning and situation awareness of emerging infectious diseases. PMID:27178645

  19. Moore's law, Dabbawalas, and pediatric cardiac care in Sri Lanka

    PubMed Central

    Samarasinghe, Duminda

    2015-01-01

    Sri Lanka is an island nation in Indian Ocean that provides free healthcare to all citizens through government healthcare system. It has commendable health indices in the region. Pediatric cardiac services have rapidly progressed over past few years helping to further bring down infant and under-five mortality rates. Lady Ridgeway Hospital for Children (LRH) is the only tertiary care referral center for children with heart disease in the country. Currently it performs approximately 1,000 cardiac catheterizations and 1,000 cardiac surgeries every year. Target is to double the surgical output to treat all children with heart diseases in a timely and appropriate manner. Being a middle-income country, this is not an easy task. Technology used in diagnosis and treatment of congenital heart diseases is rapidly advancing with its price tag. In such a setting, it is challenging to proceed to achieve this target in a resource-limited environment. PMID:26085764

  20. Moore's law, Dabbawalas, and pediatric cardiac care in Sri Lanka.

    PubMed

    Samarasinghe, Duminda

    2015-01-01

    Sri Lanka is an island nation in Indian Ocean that provides free healthcare to all citizens through government healthcare system. It has commendable health indices in the region. Pediatric cardiac services have rapidly progressed over past few years helping to further bring down infant and under-five mortality rates. Lady Ridgeway Hospital for Children (LRH) is the only tertiary care referral center for children with heart disease in the country. Currently it performs approximately 1,000 cardiac catheterizations and 1,000 cardiac surgeries every year. Target is to double the surgical output to treat all children with heart diseases in a timely and appropriate manner. Being a middle-income country, this is not an easy task. Technology used in diagnosis and treatment of congenital heart diseases is rapidly advancing with its price tag. In such a setting, it is challenging to proceed to achieve this target in a resource-limited environment. PMID:26085764

  1. Post-Tsunami Reconstruction in Sri Lanka: Houses or Housing?

    NASA Astrophysics Data System (ADS)

    Khazai, B.; Franco, G.; Ingram, J. C.; Rumbaitis del Rio, C.

    2005-12-01

    Reconstruction can be an opportunity to address longer-term livelihood vulnerability within poor communities and households, and to empower the most vulnerable. The post-tsunami reconstruction efforts in Sri Lanka can be seen on two disconnected scales. On a local scale there seems to be a growing recognition by district-level government and NGOs on the importance of households in creating social, human and financial capital, as demonstrated by many programs targeted at rebuilding livelihoods and income-generating activities. On a national scale, however, programs have revealed an emphasis on houses as the physical capital rather than housing as the arena of social and economic life. The aim of national-scale programs is to deliver tangible and quantifiable products, in the form of houses built, often without regard of whether this complements or disrupts livelihoods. One example of such a directive is the implementation of a coastal buffer zone which will ban any new construction within a 100 to 200 meter band from the ocean and allowing only structures that sustained less than 40 percent damage to remain and rebuild. In general these kind of surviving structures along the coast are businesses such as hotels and restaurants. In an island nation such as Sri Lanka, where beach front property is by and large considered low-income housing, typically inhabited by fishermen who rely on the ocean for their livelihoods, the buffer zone constitutes a drastic oversight of local processes shaping these households. The product-oriented solution on the national scale has resulted in building permanent houses for fishery communities in resettlement sites kilometers away from the ocean. The focus of this presentation will be on reconciling the need for immediate shelter needs with a long-term perspective of livelihood rehabilitation using Sri Lanka as a case study. Houses themselves are often not an immediate priority for local people, whose first need is likely to resume income

  2. Humanity at the Crossroads: Does Sri Aurobindo Offer an Alternative?*

    PubMed Central

    Singh, Shakuntala A.; Singh, Ajai R.

    2009-01-01

    In the light of Sri Aurobindo's philosophy, this paper looks into some of the problems of contemporary man as an individual, a member of society, a citizen of his country, a component of this world, and of nature itself. Concepts like Science; Nature,;Matter; Mental Being; Mana-purusa; Prana-purusa; Citta-purusa; Nation-ego and Nation-soul; True and False Subjectivism; World-state and World-union; Religion of Humanism are the focus of this paper. Nature: Beneath the diversity and uniqueness of the different elements in Nature there is an essential unity that not only allows for this diversity but even supports it. Nature is both a benefactor and a force: a benefactor, because it acts to carry out the evolution of mankind; a force, because it also supplies the necessary energy and momentum to achieve it. Natural calamities: If mankind can quieten the tsunamis and cyclones and droughts and earthquakes that rage within, and behave with care and compassion towards Nature, not exploiting, denuding, or denigrating it, there is a strong possibility that Nature too will behave with equal care and compassion towards man and spare him the natural calamities than rend him asunder. Science: The limitation of science become obvious, according to Sri Aurobindo, when we realize that it has mastered knowledge of processes and helped in the creation of machinery but is ignorant of the foundations of being and, therefore, cannot perfect our nature or our life. Science and philosophy: The insights of philosophy could become heuristic and algorithmic models for scientific experimentation. Matter: An interesting aspect of Sri Aurobindo's philosophy is his acceptance of the reality of matter even while highlighting its inadequacies; the ultimate goal, according to him, is the divination of matter itself. Purusa: If the mana-purusa (mental being) were to log on to the genuine citta-purusa (psychic formation), without necessarily logging off from the prana-purusa (frontal formation), it

  3. Case history of FAA/SRI wind shear models

    NASA Technical Reports Server (NTRS)

    Schlickenmaier, Herbert

    1987-01-01

    In order to understand the development of the FAA/SRI wind fields, it is important to understand the operating philosophy of the FAA's Wind Shear Program Office. The goal of the office was to ensure an integrated solution to the wind shear problem which addressed three area: ground based equipment and coordination; airborne systems and procedures; and weather prediction. This triply addressed goal was central to the development of the wind fields. The primary user of the wind shear modeling during the FAA's program was airborne simulation. The project requirement was to use wind shear models that resulted from accidents so that effective procedures and/or equipment could be found for hazardous wind shear encounters. The wind shear model development is discussed in detail.

  4. Coral poaching worsens tsunami destruction in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Fernando, H. J. S.; McCulley, J. L.; Mendis, S. G.; Perera, K.

    Observations of the trail of destruction of the Sumatra tsunami of 26 December 2004 indicate remarkable, small-scale spatial variations, of the order of a few kilometers, of water inundation and destruction in southwestern Sri Lanka [Shiermeier, 2005; Liu et al., 2005] that are much smaller than the tsunami wavelength of ˜100 km.For example, the town of Peraliya, was awash with an approximately 1.5-km water inundation from a wave of 10 m in height; the inundation there carried the passenger train Samudra Devi (the “Ocean Queen”) inland some 50 m, killing 1700 people. Yet,˜3 km south, in Hikkaduwa, there was a mere 2-3 m wave height, 50-m inundation and no deaths.

  5. Surveillance for antibodies to Leishmania spp. in dogs from Sri Lanka.

    PubMed

    Rosypal, A C; Tripp, S; Kinlaw, C; Hailemariam, S; Tidwell, R R; Lindsay, D S; Rajapakse, R P V J; Sreekumar, C; Dubey, J P

    2010-02-01

    The global distribution of leishmaniasis is rapidly expanding into new geographic regions. Dogs are the primary reservoir hosts for human visceral leishmaniasis caused by infection with Leishmania infantum. Natural infections with other Leishmania spp. can occur in dogs, but their role as reservoir hosts for other species of Leishmania is uncertain. Leishmania donovani is traditionally considered a visceralizing anthroponotic species; however, cutaneous leishmaniasis caused by L. donovani has been reported in Sri Lanka. In the present study, sera from 114 dogs in Sri Lanka were examined for antibodies to visceralizing Leishmania spp. Sera were tested by the canine immunochromatographic strip assays based on recombinant K39 antigen. Anti-Leishmania spp. antibodies were detectable in 1 of 114 (0.9%) dogs from Sri Lanka. Nonetheless, serological evidence suggests that leishmaniasis may be an emerging zoonosis in Sri Lanka. PMID:19803542

  6. Mixed gonadal dysgenesis in 45,X Turner syndrome with SRY gene

    PubMed Central

    Jung, Jae Yeop; Yang, Sohyoung; Jeong, Eun-Hwan; Lee, Ho-Chang; Lee, Yong-Moon; Han, Heon-Seok

    2015-01-01

    Turner syndrome is the most common chromosomal disorder in girls. Various phenotypic features show depending upon karyotype from normal female through ambiguous genitalia to male. Usually, Turner girls containing 45,X/46,XY mosaicism, or sex-determining region Y (SRY) gene may have mixed gonadal dysgenesis with various external sexual differentiation. We experienced a short statured 45,X Turner girl with normal external genitalia. Because SRY gene was positive, laparoscopic gonadectomy was performed. The dysgenetic gonads revealed bilateral ovotesticular tissues. The authors report a mixed gonadal dysgenesis case found in clinical 45,X Turner patient with positive SRY gene. Screening for SRY gene should be done even the karyotype is 45,X monosomy and external genitalia is normal. PMID:26817010

  7. New insights into SRY regulation through identification of 5' conserved sequences

    PubMed Central

    Ross, Diana GF; Bowles, Josephine; Koopman, Peter; Lehnert, Sigrid

    2008-01-01

    Background SRY is the pivotal gene initiating male sex determination in most mammals, but how its expression is regulated is still not understood. In this study we derived novel SRY 5' flanking genomic sequence data from bovine and caprine genomic BAC clones. Results We identified four intervals of high homology upstream of SRY by comparison of human, bovine, pig, goat and mouse genomic sequences. These conserved regions contain putative binding sites for a large number of known transcription factor families, including several that have been implicated previously in sex determination and early gonadal development. Conclusion Our results reveal potentially important SRY regulatory elements, mutations in which might underlie cases of idiopathic human XY sex reversal. PMID:18851760

  8. Bridgman bulk growth and scintillation measurements of SrI2:Eu2+

    NASA Astrophysics Data System (ADS)

    Hawrami, R.; Glodo, J.; Shah, K. S.; Cherepy, N.; Payne, S.; Burger, A.; Boatner, L.

    2013-09-01

    Large diameter Bridgman growth of europium activated strontium iodide SrI2:Eu2+ produces crystals with light yield of up to 115,000 ph/MeV with an excellent light yield proportionality. SrI2:Eu2+ exhibits an outstanding energy resolution of better than 3% FWHM at 662 keV. Its emission is centered at 435 nm. The scintillation decays with a 1 μs time constant for small samples and up to 5 μs to larger crystals. This paper presents successful progress made in the vertical Bridgman crystal growth of SrI2:Eu2+ and its scintillator properties. Large diameter, crack-free and transparent SrI2:Eu2+single crystals with diameters of 1 in., 1.3 in., 1.5 in. and 2 in. were all successfully grown.

  9. Fossilized diatoms in meteorites from recent falls in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Hoover, Richard B.; Wallis, Jamie; Wickramarathne, Keerthi; Samaranayake, Anil; Williams, George; Jerman, Gregory; Wallis, D. H.; Wickramasinghe, N. C.

    2013-09-01

    On December 29, 2012, a bright yellow and green fireball was observed to disintegrate over the Polonnaruwa District of North Central, Sri Lanka. Many low density, black stones were recovered soon after the observed fall from rice paddy fields near the villages of Aralaganwila and Dimbulagala. These stones were initially studied by optical microscopy methods at the Medical Research Institute in Colombo, Sri Lanka. Soon thereafter, samples were sent to the UK and to the United States. More extensive Field Emission Scanning Electron Microscopy studies were then carried out at Cardiff University and the NASA/Marshall Space Flight Center. The physico-chemical properties, elemental abundances, mineralogy and stable isotope data clearly indicate that these stones are non-terrestrial. Freshly fractured interior surfaces of the black stones have also been observed to contain the remains of fossilized diatom. Many of the diatom frustules are clearly embedded in the meteorite rock matrix and exhibit nitrogen levels below the EDX detection limits. Some of the fossil diatoms are araphid marine pennates and planktonic forms that are inconsistent with conditions associated with rice paddy fields. These observations indicate the fossilized diatoms are indigenous to the meteorites rather than post-arrival biological contaminants. The carbon content and mineralogy suggests that these stones may represent a previously ungrouped clan of carbonaceous meteorites. The extremely low density (~0.6) of the stones and their observed mineralogy was inconsistent with known terrestrial rocks (e.g., pumice, diatomite and fulgurites). The minerals detected suggest that the parent body of the Polonnaruwa stones may have been the nucleus of a comet. These observations are interpreted as supporting the Hoyle-Wickramasinghe Panspermia hypothesis and the hypothesis that diatoms and other microorganisms might be capable of living and growing in water ice and brines in comets.

  10. Frontiers of the food-energy-water trilemma: Sri Lanka as a microcosm of tradeoffs

    NASA Astrophysics Data System (ADS)

    Perrone, Debra; Hornberger, George

    2016-01-01

    Food, energy, and water are three critical resources for humanity. As climate variability, population growth, and lifestyle changes amplify the stress placed on each of the resources, the interrelationships among food, energy, and water systems become more pronounced. Political conflict, social and cultural norms, and spatial and temporal distribution of the resources add additional layers of complexity. It is in this context that the significance of understanding the impacts of water scarcity on the decisions around food and energy productions has emerged. Our work establishes tradeoff frontiers (TFs) as a method useful in illustrating the system-level tradeoffs between allocating water for food and water for energy. This paper illustrates how TFs can be used to (1) show how scarcity in water resources affects the tradeoffs between food and energy and (2) explore the political and social constraints that can move production away from what is feasible technically. We use Sri Lanka, a country where water resources are variable both in space and time and a country with relatively self-contained energy and agricultural sectors, as a microcosm of the food security, energy security, and water security trilemma. Nevertheless, our application of tradeoff frontiers is applicable widely to other systems.

  11. Effect of repeated application of fenthion as a mosquito larvicide on Nile tilapia (Oreochromis niloticus) inhabiting selected water canals in Sri Lanka.

    PubMed

    Jayasundara, Viranga K; Pathiratne, Asoka

    2008-04-01

    Health status of feral Nile tilapia following repeated applications of fenthion as a mosquito larvicide to selected water canals in Sri Lanka was assessed. With three spray applications of fenthion to the study sites at weekly intervals at the concentration recommended for mosquito control, condition factor and brain acetylcholinesterase activity of the fish were depressed in a time dependent manner. Prominent histopathological alterations displayed were gill hyperplasia and telangiectasis and vacoulation of hepatocytes. Observed ill health effects of fenthion on the fish demonstrate probable ecological risk to the fish populations inhabiting the water canals which receive repeated inputs of fenthion. PMID:18344014

  12. Crustal thickness control on Sr/Y signatures of recent arc magmas: an Earth scale perspective.

    PubMed

    Chiaradia, Massimo

    2015-01-01

    Arc magmas originate in subduction zones as partial melts of the mantle, induced by aqueous fluids/melts liberated by the subducted slab. Subsequently, they rise through and evolve within the overriding plate crust. Aside from broadly similar features that distinguish them from magmas of other geodynamic settings (e.g., mid-ocean ridges, intraplate), arc magmas display variably high Sr/Y values. Elucidating the debated origin of high Sr/Y signatures in arc magmas, whether due to mantle-source, slab melting or intracrustal processes, is instrumental for models of crustal growth and ore genesis. Here, using a statistical treatment of >23000 whole rock geochemical data, I show that average Sr/Y values and degree of maturation (MgO depletion at peak Sr/Y values) of 19 out of 22 Pliocene-Quaternary arcs correlate positively with arc thickness. This suggests that crustal thickness exerts a first order control on the Sr/Y variability of arc magmas through the stabilization or destabilization of mineral phases that fractionate Sr (plagioclase) and Y (amphibole ± garnet). In fact, the stability of these mineral phases is function of the pressure at which magma evolves, which depends on crustal thickness. The data presented show also that high Sr/Y Pliocene-Quaternary intermediate-felsic arc rocks have a distinct origin from their Archean counterparts. PMID:25631193

  13. Biological response of the sea around Sri Lanka to summer monsoon

    NASA Astrophysics Data System (ADS)

    Vinayachandran, P. N.; Chauhan, P.; Mohan, M.; Nayak, S.

    2004-01-01

    Chlorophyll-a concentration (chl a) maps derived from the Ocean Color Monitor (OCM) on board Indian Remote Sensing Satellite (IRS-P4) and Seaviewing Wide field of View sensor (SeaWiFS) show increased chl a in the waters around Sri Lanka during summer monsoon. Physical processes that can lead to the phytoplankton bloom are investigated using upper ocean temperature profiles and satellite derived winds, sea surface temperature (SST) and sea level anomalies (SLA). There is a chl a bloom attached to the southern coast of Sri Lanka accompanied by cool SST, low SLA and upsloping of isotherms towards the coast. Coastal upwelling driven by monsoon winds is identified as the physical mechanism causing nutrient enrichment in the surface layer. The Southwest Monsoon Current (SMC) which flows eastward south of Sri Lanka and then into the Bay of Bengal advects the upwelled water eastward along its path. The chl a rich waters from the Indian coast also advects along with the SMC towards Sri Lanka. East of Sri Lanka the open ocean upwelling associated with the Sri Lanka Dome is also found to be an important process that upwell nutrients.

  14. Two novel SRY missense mutations reducing DNA binding identified in XY females and their mosaic fathers

    SciTech Connect

    Schmitt-Ney, M.; Scherer, G.; Thiele, H.; KaltwaBer, P.; Bardoni, B.; Cisternino, M.

    1995-04-01

    Two novel mutations in the sex-determining gene SRY were identified by screening DNA from 30 sex-reversed XY females by using the SSCP assay. Both point mutations lead to an amino acid substitution in the DNA-binding high-mobility-group domain of the SRY protein. The first mutation, changing a serine at position 91 to glycine, was found in a sporadic case. The second mutation, leading to replacement of a highly conserved proline at position 125 with leucine, is shared by three members of the same family, two sisters and a half sister having the same father. The mutant SRY proteins showed reduced DNA-binding ability in a gel-shift assay. Analysis of lymphocyte DNA from the respective fathers revealed that they carry both the wild-type and the mutant version of the SRY gene. The fact that both fathers transmitted the mutant SRY copy to their offspring implies that they are mosaic for the SRY gene in testis as well as in blood, as a result of a mutation during early embryonic development. 30 refs., 5 figs.

  15. Crustal thickness control on Sr/Y signatures of recent arc magmas: an Earth scale perspective

    PubMed Central

    Chiaradia, Massimo

    2015-01-01

    Arc magmas originate in subduction zones as partial melts of the mantle, induced by aqueous fluids/melts liberated by the subducted slab. Subsequently, they rise through and evolve within the overriding plate crust. Aside from broadly similar features that distinguish them from magmas of other geodynamic settings (e.g., mid-ocean ridges, intraplate), arc magmas display variably high Sr/Y values. Elucidating the debated origin of high Sr/Y signatures in arc magmas, whether due to mantle-source, slab melting or intracrustal processes, is instrumental for models of crustal growth and ore genesis. Here, using a statistical treatment of >23000 whole rock geochemical data, I show that average Sr/Y values and degree of maturation (MgO depletion at peak Sr/Y values) of 19 out of 22 Pliocene-Quaternary arcs correlate positively with arc thickness. This suggests that crustal thickness exerts a first order control on the Sr/Y variability of arc magmas through the stabilization or destabilization of mineral phases that fractionate Sr (plagioclase) and Y (amphibole ± garnet). In fact, the stability of these mineral phases is function of the pressure at which magma evolves, which depends on crustal thickness. The data presented show also that high Sr/Y Pliocene-Quaternary intermediate-felsic arc rocks have a distinct origin from their Archean counterparts. PMID:25631193

  16. Emerging population issues among adolescents and youth.

    PubMed

    Abeykoon, A T; Wilson, P

    1998-02-01

    The authors "examine the emerging population issues of adolescents and youth [in Sri Lanka]. The demographic pressures have resulted in the expansion of the numbers in this age category which in turn has caused problems of employment creation. The educational expansion has brought about changes in the age at marriage and life styles, which in turn has created the need for greater attention on reproductive health issues among adolescents and youth." PMID:12294270

  17. Burden of Dengue Infection and Disease in a Pediatric Cohort in Urban Sri Lanka

    PubMed Central

    Tissera, Hasitha; Amarasinghe, Ananda; De Silva, Aruna Dharshan; Kariyawasam, Pradeep; Corbett, Kizzmekia S.; Katzelnick, Leah; Tam, Clarence; Letson, G. William; Margolis, Harold S.; de Silva, Aravinda M.

    2014-01-01

    Dengue is the most significant arthropod-borne viral infection of humans. Persons infected with dengue viruses (DENV) have subclinical or clinically apparent infections ranging from undifferentiated fever to dengue hemorrhagic fever/shock syndrome. Although recent studies estimated that the Indian subcontinent has the greatest burden of DENV infection and disease worldwide, we do not have reliable, population-based estimates of the incidence of infection and disease in this region. The goal of this study was to follow-up a cohort of 800 children living in a heavily urbanized area of Colombo, Sri Lanka to obtain accurate estimates of the incidence of DENV infection and disease. Annual blood samples were obtained from all children to estimate dengue seroprevalence at enrollment and to identify children exposed to new DENV infections during the study year. Blood was also obtained from any child in whom fever developed over the course of the study year to identify clinically apparent DENV infections. At enrollment, dengue seroprevalence was 53.07%, which indicated high transmission in this population. Over the study year, the incidence of DENV infection and disease were 8.39 (95% confidence interval = 6.56–10.53) and 3.38 (95% confidence interval = 2.24–4.88), respectively, per 100 children per year. The ratio of clinically inapparent to apparent infections was 1.48. These results will be useful for obtaining more accurate estimates of the burden of dengue in the region and for making decisions about testing and introduction of vaccines. PMID:24865684

  18. The Impacts Of The Indian Ocean Tsunami On Coastal Ecosystems And Resultant Effects On The Human Communities Of Sri Lanka

    NASA Astrophysics Data System (ADS)

    Ingram, J.; Rumbaitis-del Rio, C.; Franco, G.; Khazai, B.

    2005-12-01

    The devastating tsunami that hit Sri Lanka on December 26, 2004 has demonstrated vividly the inter-connections between social and ecological resilience. Before the tsunami, the coastal zone of Sri Lanka was inhabited by predominantly poor populations, most of whom were directly dependent upon coastal natural resources, such as fisheries and coconut trees, for supporting their livelihoods. Many of these people have now lost their livelihoods through the destruction of their boats and nets for fishing, the contamination of drinking sources, homes, family members and assets. This presentation focuses on observations of the tsunami impacts on both social and ecological communities made along the affected coastline of Sri Lanka in April-May 2005. This assessment recorded patterns of ecological resistance and damage resulting from the tsunami in relation to damage on the human environment, with an exploration of the physical factors that may have contributed to vulnerability or resistance. This work also involved a preliminary assessment of the resilience and recovery of different natural resource based livelihood strategies following the disaster and an exploration of livelihood possibilities in proposed resettlement sites. From observations made in this and other recent studies, it is apparent that intact ecosystems played a vital role in protection from the impact of the tsunami and are vital for supporting people as they seek to rebuild their livelihoods. However, certain structural and biological characteristics appear to offer certain tree species, such as coconut (Cocos nucifera), an advantage in surviving such events and have been important for providing food and drink to people in the days after the tsunami. Areas where significant environmental damage had occurred prior to the tsunami or where there were few natural defenses present to protect human communities, devastation of homes and lives was extremely high. Although, there is evidence that many previously

  19. Hypospadias in a male (78,XY; SRY-positive) dog and sex reversal female (78,XX; SRY-negative) dogs: clinical, histological and genetic studies.

    PubMed

    Switonski, M; Payan-Carreira, R; Bartz, M; Nowacka-Woszuk, J; Szczerbal, I; Colaço, B; Pires, M A; Ochota, M; Nizanski, W

    2012-01-01

    Hypospadias is rarely reported in dogs. In this study we pre-sent 2 novel cases of this disorder of sexual development and, in addition, a case of hereditary sex reversal in a female with an enlarged clitoris. The first case was a male Moscow watchdog with a normal karyotype (78,XY) and the presence of the SRY gene. In this dog, perineal hypospadias, bilateral inguinal cryptorchidism and testes were observed. The second case, representing the Cocker spaniel breed, had a small penis with a hypospadic orifice of the urethra, bilateral cryptorchidism, testis and a rudimentary gonad inside an ovarian bursa, a normal female karyotype (78,XX) and a lack of the SRY gene. This animal was classified as a compound sex reversal (78,XX, SRY-negative) with the hypospadias syndrome. The third case was a Cocker spaniel female with an enlarged clitoris and internally located ovotestes. Cytogenetic and molecular analyses revealed a normal female karyotype (78,XX) and a lack of the SRY gene, while histology of the gonads showed an ovotesticular structure. This case was classified as a typical hereditary sex reversal syndrome (78,XX, SRY-negative). Molecular studies were focused on coding sequences of the SRY gene (case 1) and 2 candidates for monogenic hypospadias, namely MAMLD1 (mastermind-like domain containing 1) and SRD5A2 (steroid-5-alpha-reductase, alpha polypeptide 2). Sequencing of the entire SRY gene, including 5'- and 3'-flanking regions, did not reveal any mutation. The entire coding sequence of MAMLD1 and SRD5A2 was analyzed in all the intersexes, as well as in 4 phenotypically normal control dogs (3 females and 1 male). In MAMLD1 2 SNPs, including 1 missense substitution in exon 1 (c.128A>G, Asp43Ser), were identified, whereas in SRD5A2 7 polymorphisms, including 1 missense SNP (c.358G>A, Ala120Thr), were found. None of the identified polymorphisms cosegregated with the intersexual phenotype, thus, we cannot confirm that hypospadias may be associated with polymorphism

  20. Vulnerability analysis in terms of food insecurity and poverty using GIS and remote sensing technology applied to Sri Lanka

    NASA Astrophysics Data System (ADS)

    Shahriar, Pervez M.; Ramachandran, Mahadevan; Mutuwatte, Lal

    2003-03-01

    It is becoming increasingly recognized that computer methods such as models and Geographic Information Systems (GIS) can be valuable tools for analyzing a geographical area in terms of it's hazards vulnerability, Vulnerability is an important aspect of households' experience of poverty. The measurement and analysis of poverty, inequality and vulnerability are crucial for cognitive purposes (to know what the situation is), for analytical purposes (to understand the factors determining this situation), for policy making purposes (to design interventions best adapted to the issues), and for monitoring and evaluation purposes (to assess whether current policies are effective, and whether the situation is changing). Here vulnerability defined as the probability or risk today of being in poverty - or falling deeper into poverty - in the future. Vulnerability is a key dimension of well being since it affects individuals' behavior (in terms of investment, production patterns, coping strategies) and their perception of their own situation. This study has been conducted with the joint collaboration of World Food Programme (WFP) and International Water Management Institute (IWMI) in Sri Lanka for identifying regions and population which are food insecure, for analyzing the reasons for vulnerability to food insecurity in order to provide decision-makers with information to identify possible sectors of intervention and for identifying where and for whom food aid can be best utilized in Sri Lanka. This new approach integrates GIS and Remote sensing with other statistical packages to allow consideration of more spatial/physical parameters like accessibility to economic resources, particularly land and the assets of the built environment, creating employment, and attracting investment in order to improve the quality and quantity of goods and services for the analysis which leads the analysis to represent the real scenario. For this study a detailed topographic data are being used

  1. Molecular characterisation and disease severity of leptospirosis in Sri Lanka.

    PubMed

    Bandara, Kanchana Kumari; Weerasekera, Manjula; Gunasekara, Chinthika P; Ranasinghe, Nilantha; Marasinghe, Chamil; Fernando, Neluka

    2015-06-01

    Leptospirosis is a re-emerging zoonotic disease all over the world, important in tropical and subtropical areas. A majority of leptospirosis infected patients present as subclinical or mild disease while 5-10% may develop severe infection requiring hospitalisation and critical care. It is possible that several factors, such as the infecting serovar, level of leptospiraemia, host genetic factors and host immune response, may be important in predisposition towards severe disease. Different Leptospira strains circulate in different geographical regions contributing to variable disease severity. Therefore, it is important to investigate the circulating strains at geographical locations during each outbreak for epidemiological studies and to support the clinical management of the patients. In this study immunochromatography, microscopic agglutination test and polymerase chain reaction were used to diagnose leptospirosis. Further restriction fragment length polymorphism and DNA sequencing methods were used to identify the circulating strains in two selected geographical regions of Sri Lanka. Leptospira interrogans, Leptospira borgpetersenii and Leptospira kirschneri strains were identified to be circulating in western and southern provinces. L. interrogans was the predominant species circulating in western and southern provinces in 2013 and its presence was mainly associated with renal failure. PMID:26061234

  2. Managing shallow aquifers in the dry zone of Sri Lanka.

    PubMed

    Sood, Aditya; Manthrithilake, Herath; Siddiqui, Salman; Rajah, Ameer; Pathmarajah, S

    2015-07-01

    This study looks at the groundwater issues in the dry zone of Sri Lanka and shows how the use of remote sensing with high-resolution images can help in groundwater management. A new approach is developed for automatic extraction of the location of agro-wells using high-spatial-resolution satellite imageries. As an example, three pilot sites in three different aquifer systems in the country are considered, and their high-resolution images are analyzed over two temporal time periods. The analysis suggests that the well density in all three regions has increased over the last few years, indicating higher levels of groundwater extraction. Using the well inventory developed by this new approach, the water budgeting was prepared for the mainland of Jaffna Peninsula. The analysis shows a wide variation in well density in the Jaffna Peninsula, ranging from (as little as) less than 15 wells per square kilometer to (as high as) more than 200 wells per square kilometer. Calculations made for the maximum allowable water extraction in each administrative division of Jaffna show that less than 3 h of daily extraction per well is possible in some districts. This points to an increasing pressure on groundwater resources in the region and thus highlights the importance of understanding groundwater budgets for sustainable development of the aquifers. PMID:26041062

  3. Molecular characterisation and disease severity of leptospirosis in Sri Lanka

    PubMed Central

    Bandara, Kanchana Kumari; Weerasekera, Manjula; Gunasekara, Chinthika P; Ranasinghe, Nilantha; Marasinghe, Chamil; Fernando, Neluka

    2015-01-01

    Leptospirosis is a re-emerging zoonotic disease all over the world, important in tropical and subtropical areas. A majority of leptospirosis infected patients present as subclinical or mild disease while 5-10% may develop severe infection requiring hospitalisation and critical care. It is possible that several factors, such as the infecting serovar, level of leptospiraemia, host genetic factors and host immune response, may be important in predisposition towards severe disease. Different Leptospira strains circulate in different geographical regions contributing to variable disease severity. Therefore, it is important to investigate the circulating strains at geographical locations during each outbreak for epidemiological studies and to support the clinical management of the patients. In this study immunochromatography, microscopic agglutination test and polymerase chain reaction were used to diagnose leptospirosis. Further restriction fragment length polymorphism and DNA sequencing methods were used to identify the circulating strains in two selected geographical regions of Sri Lanka. Leptospira interrogans, Leptospira borgpetersenii and Leptospira kirschneri strains were identified to be circulating in western and southern provinces. L. interrogans was the predominant species circulating in western and southern provinces in 2013 and its presence was mainly associated with renal failure. PMID:26061234

  4. A modern terrestrial phosphorite-an example from Sri Lanka

    NASA Astrophysics Data System (ADS)

    Dahanayake, Kapila; Subasinghe, S. M. N. D.

    1989-02-01

    At Eppawala in Central Sri Lanka, a thick weathering profile is mined for use as phosphate fertilizer. Recent tropical subaerial weathering processes have produced a phosphate-enriched horizon in the weathering profile which has developed on a Precambrian apatite marble formation. The enriched horizon with P 2O 5 compositions ranging from 10 to 40% is formed essentially of laminar phoscretes occurring in a network of sinkholes. Detailed examination of the laminar phoscretes reveals that primary metamorphic apatite crystals occur in association with phosphatic allochems such as coated grains, ooids, pisoids and intraclasts in a finely layered groundmass. It has been observed that the primary apatite grains released from the parent apatite marble due to tropical weathering processes have been deposited in sinkholes where nutrient-rich percolating meteoric waters were precipitating secondary apatite. Subsequent diagenetic processes active in such sinkhole sedimentary environments have produced the phosphatic allochems characteristic of secondary phosphate mineralization. The allochems together with their mineralized groundmass and the associated primary apatite grains have given rise to the Eppawala phosphorite deposit.

  5. E-waste issues in Sri Lanka and the Basel Convention.

    PubMed

    Suraweera, Inoka

    2016-03-01

    E-waste is hazardous, complex and expensive to treat in an environmentally sound manner. The management of e-waste is considered a serious challenge in both developed and developing countries and Sri Lanka is no exception. Due to significant growth in the economy and investments and other reasons the consumption of electronic and electrical equipment in Sri Lanka has increased over the years resulting in significant generation of e-waste. Several initiatives such as introduction of hazardous waste management rules, ratification of the Basel Convention in 1992 and the introduction of a National Corporate E-waste Management Program have been undertaken in Sri Lanka to manage e-waste. Strengthening policy and legislation, introducing methods for upstream reduction of e-waste, building capacity of relevant officers, awareness raising among school children and the general public and development of an e-waste information system are vital. Research on e-waste needs to be developed in Sri Lanka. The health sector could play a leading role in the provision of occupational health and safety for e-waste workers, advocacy, capacity building of relevant staff and raising awareness among the general public about e-waste. Improper e-waste management practices carried out by informal sector workers need to be addressed urgently in Sri Lanka. PMID:26943598

  6. Multiple copies of SRY on the large Y chromosome of the Okinawa spiny rat, Tokudaia muenninki.

    PubMed

    Murata, Chie; Yamada, Fumio; Kawauchi, Norihiro; Matsuda, Yoichi; Kuroiwa, Asato

    2010-09-01

    The Okinawa spiny rat, Tokudaia muenninki, is the only species with a Y chromosome in the genus Tokudaia. Its phylogenic relationship with two XO/XO species, Tokudaia osimensis and Tokudaia tokunoshimensis, lacking a Y chromosome and the mammalian sex-determining gene SRY, is unknown. Furthermore, there has been little cytogenetic analysis of the sex chromosomes in T. muenninki. Therefore, we constructed molecular phylogenetic trees with nucleotide sequences of cyt b, RAG1, and IRBP. All trees strongly supported that T. muenninki was the first to diverge from the Tokudaia ancestor, indicating that loss of the Y chromosome and SRY occurred in the common ancestor of the two XO/XO species after T. muenninki diverged. We found that the X and Y chromosomes of T. muenninki consisted of large euchromatic and heterochromatic regions by conducting G- and C-banding analyses. PCR, Southern blotting, and FISH revealed that T. muenninki males had multiple SRY copies on the long arm of the Y chromosome. At least three of 24 SRY sequences contained a complete open reading frame (ORF). A species-specific substitution from alanine to serine was found in all copies at the DNA-binding surface within the HMG-box, suggesting that it occurred in an original SRY. PMID:20574822

  7. Mammalian Testis-determining Factor SRY and the Enigma of Inherited Human Sex Reversal

    PubMed Central

    Phillips, Nelson B.; Racca, Joseph; Chen, Yen-Shan; Singh, Rupinder; Jancso-Radek, Agnes; Radek, James T.; Wickramasinghe, Nalinda P.; Haas, Elisha; Weiss, Michael A.

    2011-01-01

    Mammalian testis-determining factor SRY contains a high mobility group box, a conserved eukaryotic motif of DNA bending. Mutations in SRY cause XY gonadal dysgenesis and somatic sex reversal. Although such mutations usually arise de novo in spermatogenesis, some are inherited and so specify male development in one genetic background (the father) but not another (the daughter). Here, we describe the biophysical properties of a representative inherited mutation, V60L, within the minor wing of the L-shaped domain (box position 5). Although the stability and DNA binding properties of the mutant domain are similar to those of wild type, studies of SRY-induced DNA bending by subnanosecond time-resolved fluorescence resonance energy transfer (FRET) revealed enhanced conformational fluctuations leading to long range variation in bend angle. 1H NMR studies of the variant protein-DNA complex demonstrated only local perturbations near the mutation site. Because the minor wing of SRY folds on DNA binding, the inherited mutation presumably hinders induced fit. Stopped-flow FRET studies indicated that such frustrated packing leads to accelerated dissociation of the bent complex. Studies of SRY-directed transcriptional regulation in an embryonic gonadal cell line demonstrated partial activation of downstream target Sox9. Our results have demonstrated a nonlocal coupling between DNA-directed protein folding and protein-directed DNA bending. Perturbation of this coupling is associated with a genetic switch poised at the threshold of activity. PMID:21849498

  8. Why large porphyry Cu deposits like high Sr/Y magmas?

    PubMed Central

    Chiaradia, Massimo; Ulianov, Alexey; Kouzmanov, Kalin; Beate, Bernardo

    2012-01-01

    Porphyry systems supply most copper and significant gold to our economy. Recent studies indicate that they are frequently associated with high Sr/Y magmatic rocks, but the meaning of this association remains elusive. Understanding the association between high Sr/Y magmatic rocks and porphyry-type deposits is essential to develop genetic models that can be used for exploration purposes. Here we present results on a Pleistocene volcano of Ecuador that highlight the behaviour of copper in magmas with variable (but generally high) Sr/Y values. We provide indirect evidence for Cu partitioning into a fluid phase exsolved at depths of ~15 km from high Sr/Y (>70) andesitic magmas before sulphide saturation. This lends support to the hypothesis that large amounts of Cu- and S-bearing fluids can be accumulated into and released from a long-lived high Sr/Y deep andesitic reservoir to a shallower magmatic-hydrothermal system with the potential of generating large porphyry-type deposits. PMID:23008750

  9. Agricultural Innovation Systems (AIS): A Study of Stakeholders and Their Relations in System of Rice Intensification (SRI)

    ERIC Educational Resources Information Center

    Suchiradipta, Bhattacharjee; Raj, Saravanan

    2015-01-01

    Purpose: This paper identifies the stakeholders of System of Rice Intensification (SRI), their roles and actions and the supporting and enabling environment of innovation in the state as the elements of the Agricultural Innovation Systems (AIS) in SRI in Tripura state of India and studies the relationship matrix among the stakeholders.…

  10. 77 FR 69592 - U.S. Multi-Sector Trade Mission to South India and Sri Lanka

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-20

    ... Sri Lanka (Colombo) February 3-8, 2013, published at 77 FR 48499, August 14, 2012 to revise the... Mission to Chennai and Cochin, India and Colombo, Sri Lanka on February 3-8, 2013, published at 77 FR 48499, August 14, 2012, as previously amended by notice at 77 FR 59899 (Oct. 1, 2012)...

  11. Implications of global warming for regional climate and water resources of tropical islands: Case studies over Sri Lanka and Puerto Rico

    NASA Astrophysics Data System (ADS)

    Mawalagedara, R.; Kumar, D.; Oglesby, R. J.; Ganguly, A. R.

    2013-12-01

    The IPCC AR4 identifies small islands as particularly vulnerable to climate change. Here we consider the cases of two tropical islands: Sri Lanka in the Indian Ocean and Puerto Rico in the Caribbean. The islands share a predominantly tropical climate with diverse topography and hence significant spatial variability of regional climate. Seasonal variability in temperatures is relatively small, but spatial variations can be large owing to topography. Precipitation mechanisms and patterns over the two islands are different however. Sri Lanka receives a majority of the annual rainfall from the summer and winter monsoons, with convective rainfall dominating in the inter-monsoon period. Rainfall generating mechanisms over Puerto Rico can range from orographic lifting, disturbances embedded in Easterly waves and synoptic frontal systems. Here we compare the projected changes in the regional and seasonal means and extremes of temperature and precipitation over the two islands during the middle of this century with the present conditions. Two 5-year regional climate model runs for each region, representing the present (2006-2010) and future (2056-2060) conditions, are performed using the Weather Research and Forecasting model with the lateral boundary conditions provided using the output from CCSM4 RCP8.5 greenhouse gas emissions pathway simulation from the CMIP5 ensemble. The consequences of global warming for water resources and the overall economy are examined. While both economies have substantial contributions from tourism, there are major differences: The agricultural sector is much more important over Sri Lanka compared to Puerto Rico, while the latter exhibits no recent growth in population or in urbanization trends unlike the former. Policy implications for water sustainability and security are discussed, which highlight how despite the differences, certain lessons learned may generalize across the two relatively small tropical islands, which in turn have diverse

  12. The large tsunami of 26 December 2004: Field observations and eyewitnesses accounts from Sri Lanka, Maldives Is. and Thailand

    NASA Astrophysics Data System (ADS)

    Papadopoulos, Gerassimos A.; Caputo, Riccardo; McAdoo, Brian; Pavlides, Spyros; Karastathis, Vassilios; Fokaefs, Anna; Orfanogiannaki, Katerina; Valkaniotis, Sotiris

    2006-02-01

    Post-event field surveys were conducted and measurements were taken in Sri Lanka and Maldives about two weeks after the catastrophic Indian Ocean tsunami of 26 December 2004. The measurements taken were cross-checked after interviewing with local people. In the southwest, south and east coastal zones of Sri Lanka maximum water levels ranging from h = 3 m to h = 11 m a.m.s.l. were estimated. The highest values observed were in the south of the island: Galle h ˜ 10 m, Hambantota h ˜ 11m. Maximum inundation of d ˜ 2 km was observed in Hambantota. The heavy destruction and thousands of victims caused in coastal communities, buildings and infrastructure, like railways and bridges, is attributed not only to physical parameters, like the strength of the tsunami hydrodynamic flow, coastal geomorphology and the wave erosional action in soil, but also to anthropogenic factors including the increased vulnerability of the non-RC buildings and the high population density. Local people usually described the tsunami as a series of three main waves. The leading wave phase was only a silent sea level rise of h ≤ 1.5 m and d ≤ 150 m, while the second wave was the strongest one. The first two waves occurred between 09:00 and 09:30 local time, depending on the locality. It is well documented that near Galle, southern part, the strong wave arrived at 09:25:30. In the west coast the third wave was a late arrival which possibly represents reflection phases. In Maldives, three waves were also reported to arrive between 09:00 and 09:30 local time. Maximum water level was only h ˜ 3 m in Laamu Atoll, which is interpreted by the wave amplitude damping by the coral reef to the east of the island complex as well as to that the tsunami did not arrived at high tide time. Damage was observed in several islands of Maldives but this was minimal as compared to the heavy destruction observed in Sri Lanka. About 25 Greek eyewitnesses, who happened to experience the tsunami attack in Padong and

  13. Leishmania donovani causing cutaneous leishmaniasis in Sri Lanka: a wolf in sheep's clothing?

    PubMed

    Karunaweera, Nadira D

    2009-10-01

    Research involving leishmaniasis, a newly established disease in Sri Lanka, has focused mostly on parasitological and clinical factors, with inadequate understanding of other aspects, including its epidemiology and vector. The escalation in the spread of cutaneous leishmaniasis cases within Sri Lanka and the close resemblance (genotypic and phenotypic) between the local parasite Leishmania donovani MON-37 and the parasite causing visceral leishmaniasis in India (L. donovani MON-2), underscored by the more recent case reports of autochthonous cases of visceral and mucocutaneous-like disease, are clear warnings to the health authorities, scientists and policy makers. An effective control strategy is needed to contain further spread of cutaneous disease and avert a more-virulent form of leishmaniasis becoming endemic in Sri Lanka. PMID:19734098

  14. A Clinical Case of an SRY-Positive Intersex/Hermaphrodite Holstein Cattle.

    PubMed

    Bresciani, Carla; Parma, Pietro; De Lorenzi, Lisa; Di Ianni, Francesco; Bertocchi, Mara; Bertani, Valeria; Cantoni, Anna Maria; Parmigiani, Enrico

    2015-01-01

    A single-born, 15-month-old Holstein cattle, diagnosed as hermaphrodite, was investigated for estrous cycle, hormonal profiles, karyotype, presence of SRY, as well as anatomopathological and histological aspects. Normal continuous estrous cycles and basal testosterone levels were reported. Necropsy showed the presence of a female genital tract that mismatched a vulvar opening and a male pelvic urethra continued within a penis. Moreover, we observed islands of seminiferous tubules with the presence of germline cells, 2 pampiniform plexi, the corpus cavernosum, the penile urethra, the corpus spongiosum and the glans. Cytogenetic analyses of the blood cells showed an XX karyotype, while the molecular analyses revealed the presence of the SRY gene in several tissues, including blood. This is the first report in the scientific literature of an SRY-positive hermaphrodite Holstein cattle with continuous ovarian cycles. PMID:26418730

  15. The assistant medical officer in Sri Lanka: mid-level health worker in decline.

    PubMed

    De Silva, Vijitha; Strand de Oliveira, Justine; Liyanage, Mahinda; Østbye, Truls

    2013-09-01

    The history of Assistant Medical Officers (AMOs) in Sri Lanka can be traced back to the 1860s. Their training from the beginning followed an allopathic, 'evidence based' model. AMOs have played a key role in rural and peripheral health care, through staffing of government central dispensaries and maternity homes and may have contributed to Sri Lanka's favorable health outcomes. While there are currently approximately 2000 AMOs, their training course was discontinued in 1995. It was argued that the quality of care provided by the AMOs is substandard relative to that of physicians. The success, rapid expansion and integration of physician assistant programs into the US health care system have recently spurred other countries to introduce similar programs. This paper reviews Sri Lanka's move in the opposite direction, phasing out the AMO profession, without any research into their contributions to access to interprofessional primary health care and positive health outcomes. PMID:23659623

  16. Fabrication and characterization of cubic SrI2(Eu) scintillators for use in array detectors

    NASA Astrophysics Data System (ADS)

    Shimazoe, K.; Koyama, A.; Takahashi, H.; Sakuragi, S.; Yamasaki, Y.

    2016-02-01

    Strontium iodide (SrI2(Eu)) is a promising spectroscopic detector for use in both nuclear security and medical imaging owing to its excellent energy resolution and low internal background radiation. A cubic form is preferable when coupling with a silicon-based photosensor in order to build an array detector for use in applications such as Compton cameras. Here, cubic SrI2(Eu) crystals with 10 mm sides were fabricated and evaluated. The cubic SrI2(Eu) samples coupled to an avalanche photodiode exhibited an energy resolution of approximately 3.6% at 662 keV when using a shaping time of 3 μs. An increase in light output and an improvement of energy resolution were also observed at lower temperatures. The excellent energy resolution of these devices indicates that these crystals are promising potential detectors for use in Compton cameras and other imaging detectors.

  17. The population slide.

    PubMed

    Mukerjee, M

    1998-12-01

    The level of total fertility in Bangladesh has fallen from 7 in 1975 to 3 today, the sharpest fertility transition in South Asia. Fertility decline in Bangladesh and Nepal follows such transition occurring first in Sri Lanka, then in India. While in Western countries, levels of fertility began to fall once an advanced stage of development had been reached, these new declines in South Asia are not directly correlated with indicators of development such as increased literacy or the alleviation of poverty. Bangladesh has experienced major fertility decline despite being one of the world's 20 poorest countries. Fertility decline in Bangladesh may be attributed to a combination of an effective government family planning program, a general desire among Bangladesh's population to bear fewer children, reductions in mortality, the availability of microcredit, changes in women's status, and the provision of health and family planning information over the radio 6 hours per day. PMID:9867622

  18. Inherited human sex reversal due to impaired nucleocytoplasmic trafficking of SRY defines a male transcriptional threshold

    PubMed Central

    Chen, Yen-Shan; Racca, Joseph D.; Phillips, Nelson B.; Weiss, Michael A.

    2013-01-01

    Human testis determination is initiated by SRY (sex determining region on Y chromosome). Mutations in SRY cause gonadal dysgenesis with female somatic phenotype. Two subtle variants (V60L and I90M in the high-mobility group box) define inherited alleles shared by an XY sterile daughter and fertile father. Whereas specific DNA binding and bending are unaffected in a rat embryonic pre-Sertoli cell line, the variants exhibited selective defects in nucleocytoplasmic shuttling due to impaired nuclear import (V60L; mediated by Exportin-4) or export (I90M; mediated by chromosome region maintenance 1). Decreased shuttling limits nuclear accumulation of phosphorylated (activated) SRY, in turn reducing occupancy of DNA sites regulating Sertoli-cell differentiation [the testis-specific SRY-box 9 (Sox9) enhancer]. Despite distinct patterns of biochemical and cell-biological perturbations, V60L and I90M each attenuated Sox9 expression in transient transfection assays by twofold. Such attenuation was also observed in studies of V60A, a clinical variant associated with ovotestes and hence ambiguity between divergent cell fates. This shared twofold threshold is reminiscent of autosomal syndromes of transcription-factor haploinsufficiency, including XY sex reversal associated with mutations in SOX9. Our results demonstrate that nucleocytoplasmic shuttling of SRY is necessary for robust initiation of testicular development. Although also characteristic of ungulate orthologs, such shuttling is not conserved among rodents wherein impaired nuclear export of the high-mobility group box and import-dependent phosphorylation are compensated by a microsatellite-associated transcriptional activation domain. Human sex reversal due to subtle defects in the nucleocytoplasmic shuttling of SRY suggests that its transcriptional activity lies near the edge of developmental ambiguity. PMID:24003159

  19. Parasitic infections in freshwater ornamental fish in Sri Lanka.

    PubMed

    Thilakaratne, I D S I P; Rajapaksha, G; Hewakopara, A; Rajapakse, R P V J; Faizal, A C M

    2003-03-31

    A total of 1520 ornamental fish of 13 species from 26 export farms in Sri Lanka were collected between October 1999 and March 2000 and examined for parasites. Fish species examined were guppy Poecilia reticulata, goldfish Carassius auratus, platy Xiphophorus maculatus, molly Poecilia sphenops, angel Pterophyllum scalare, swordtail Xiphophorus helleri, tetras Hyphessobrycon species, barbs Capeota and Puntius spp., gourami Colisa sp., carp Cyprinus carpio, fighters Betta spelendens and others (Brachydanio and Astronotus spp.). Nine species of monogenean trematodes (Dactylogyrus extensus, Dactylogyrus cf. extensus, D. vastator, Dactylogyrus cf. vastator Dactylogyrus spp., Gyrodactylus turnbulli, G. katherineri, Gyrodactylus cf. katherineri, Gyrodactylus spp.), 7 protozoan species (Trichodina nigra, Trichodina spp., Tetrahymena corlissi, T. pyriformis, Ichthyophthirius multifiliis, Ichthyobodo necator, Piscinoodinium spp.), 3 species of copepod arthropods (Lernaea cyprinacea, Ergasilus ceylonensis, Argulus foliaceus), 1 metacercarial stage of a digenean trematode (Centrocestus spp.) and 1 nematode (Capillaria spp.) were identified. Parasites were found in fish from 23 of the 26 farms with an overall prevalence of parasitism in 45.3% of fish. The variation in farm prevalence among different parasites was significant (p < 0.01). Fish infection rates with monogenean trematodes, protozoans, copepod crustaceans, digenean trematodes and nematodes were 28.3, 18.4, 4.8, 0.8 and 0.4%, respectively. In all, 50 out of 590 (50/590) guppies were infected with Tetrahymena, compared with 13/930 for all other species, which is a statistically significant result (p < 0.01). Similarly, 13/44 and 18/44 carp were infected with Argulus foliaceus and Lernaea cyprinacea, compared with 7/1476 and 15/1476, respectively, for all other species combined (p < 0.01). Capillaria spp. was found only in guppies (4/590) and angel fish (3/92) while Centrocestus spp. was found in goldfish (12/153) only

  20. Molecular characterization of cyanobacterial diversity in Lake Gregory, Sri Lanka

    NASA Astrophysics Data System (ADS)

    Magana-Arachchi, Dhammika; Wanigatunge, Rasika; Liyanage, Madhushankha

    2011-07-01

    Eutrophication or the process of nutrient enrichment of stagnant waters due to excessive use of fertilizer is becoming a critical issue worldwide. Lake Gregory, an artificial lake situated in Nuwara Eliya, Sri Lanka was once a very attractive landscape feature and recreational area attracting a large number of visitors. Rapid urbanization in surrounding areas and the consequent intensification of agricultural and industrial activities led to eutrophication and siltation in the lake. Present study was conducted to detect cyanobacterial diversity and their ability to produce hepatotoxic microcystins using polymerase chain reaction (PCR)-based techniques. Twenty five water samples (surface and bottom) were collected from the lake and total nitrogen and total carbon were estimated. Cyanobacterial cultures were grown in appropriate media and microscopic observations were used to determine the morphological diversity of cyanobacteria isolated from different sites. Genomic DNA was isolated and purified from cyanobacteria using Boom's method. DNA samples were analyzed by PCR with oligonucleotide primers for 16S rRNA gene and mcyA gene of the operon that encodes a microcystin synthetase. The 16S rRNA gene sequences revealed the presences of cyanobacteria belong to Synechococcus sp., Microcystis aeruginosa, Calothrix sp., Leptolyngbya sp., Limnothrix sp., order Oscillatoriales and order Chroococcales. The sequences obtained from this study were deposited in the database under the accession numbers (GenBank: GU368104-GU368116). PCR amplification of mcyA primers indicated the potential for toxin formation of isolated M. aeruginosa from Lake Gregory. This preliminary study shows that the Lake Gregory is under the potential risk of cyanobacterial toxicity. Clearly more work is needed to extend this finding and clarify if other cyanobacterial isolates have genetic potential to produce microcystin since this lake is utilized for recreational activities.

  1. Preventing ragging: outcome of an integrated programme in a medical faculty in Sri Lanka.

    PubMed

    Lekamwasam, Sarath; Rodrigo, Mahinda; Wickramathilake, Madhu; Wijesinghe, Champa; Wijerathne, Gaya; Silva, Aruna De; Napagoda, Mayuri; Attanayake, Anoja; Perera, Clifford

    2015-01-01

    Ragging is prevalent in higher educational institutes in Sri Lanka and the deaths of some new entrants in the past have been directly linked to physical and emotional torture caused by cruel acts of ragging. Although there are general anti-ragging rules in place, the effectiveness of these measures is unknown. We developed an action plan to prevent ragging by integrating the views of the major stakeholders, implemented the plan and assessed its success. This article highlights the action plan and its success in a medical faculty in southern Sri Lanka. PMID:26322639

  2. Malaria Eradication and Educational Attainment: Evidence from Paraguay and Sri Lanka†

    PubMed Central

    Lucas, Adrienne M.

    2013-01-01

    Mid-twentieth century malaria eradication campaigns largely eliminated malaria from Paraguay and Sri Lanka. Using these interventions as quasi-experiments, I estimate malaria’s effect on lifetime female educational attainment through the combination of pre-existing geographic variation in malarial intensity and cohort exposure based on the timing of the national anti-malaria campaigns. The estimates from Sri Lanka and Paraguay are similar and indicate that malaria eradication increased years of educational attainment and literacy. The similarity of the estimates across the countries reinforces our confidence in the validity of the identification strategy. PMID:23946866

  3. Proportion of lower limb fungal foot infections in patients with type 2 diabetes at a tertiary care hospital in Sri Lanka

    PubMed Central

    Wijesuriya, T. M.; Weerasekera, M. M.; Kottahachchi, J.; Ranasinghe, K. N. P.; Dissanayake, M. S. S.; Prathapan, S.; Gunasekara, T. D. C. P.; Nagahawatte, A.; Guruge, L. D.; Bulugahapitiya, U.; Fernando, S. S. N.

    2014-01-01

    Background: Superficial fungal foot infection (SFFI) in diabetic patients increases the risk of developing diabetic foot syndrome. Sixteen percent of urban population is suffering from diabetes in Sri Lanka. As the diabetes patients are more prone to get fungal foot infections, early intervention is advisable owing to the progressive nature of the infection. There is no data on the prevalence of SFFIs in diabetic patients in Sri Lanka. Objective: To determine the etiological agents causing SFFI in patients with type 2 diabetes. Materials and Methods: Three hundred eighty five diabetic patients were included. Nail clippings and swabs were collected from the infected sites using the standard protocol. Laboratory identification was done and pathogens were identified to the species level by morpho physiological methods. Results: Clinically 295 patients showed SFFI, of which 255 (86%) were mycologically confirmed for infection. Out of 236 direct microscopy (KOH) positives, 227 (96%) were culture positive. Two hundred and fifty one patients (98%) with SFFI had diabetes for more than 10 years. Of the patients with SFFIs 92% had >100 mg/dl FBS and 81% had >140 mg/dl PPBS levels and 80% had both elevated FBS and PPBS. Non-dermatophyte fungal species were the commonest pathogens followed by yeast and dermatophytes. Conclusion: Aspergillus niger was the commonest pathogen followed by Candida albicans. SFFIs were seen significantly with the increasing age, gender, duration of diabetes and with less controlled glycaemic level. PMID:24701432

  4. High lethality and minimal variation after acute self-poisoning with carbamate insecticides in Sri Lanka – implications for global suicide prevention

    PubMed Central

    Lamb, Thomas; Selvarajah, Liza R.; Mohamed, Fahim; Jayamanne, Shaluka; Gawarammana, Indika; Mostafa, Ahmed; Buckley, Nicholas A.; Roberts, Michael S.; Eddleston, Michael

    2016-01-01

    Abstract Background: Highly hazardous organophosphorus (OP) insecticides are responsible for most pesticide poisoning deaths. As they are removed from agricultural practice, they are often replaced by carbamate insecticides of perceived lower toxicity. However, relatively little is known about poisoning with these insecticides. Methods: We prospectively studied 1288 patients self-poisoned with carbamate insecticides admitted to six Sri Lankan hospitals. Clinical outcomes were recorded for each patient and plasma carbamate concentration measured in a sample to confirm the carbamate ingested. Findings: Patients had ingested 3% carbofuran powder (719), carbosulfan EC25 liquid (25% w/v, 389), or fenobucarb EC50 liquid (50% w/v, 127) formulations, carbamate insecticides of WHO Toxicity Classes Ib, II, and II, respectively. Intubation and ventilation was required for 183 (14.2%) patients while 71 (5.5%) died. Compared with carbofuran, poisoning with carbosulfan or fenobucarb was associated with significantly higher risk of death [carbofuran 2.2%; carbosulfan 11.1%, OR 5.5 (95% CI 3.0–9.8); fenobucarb 6.3%, OR 3.0 (1.2–7.1)] and intubation [carbofuran 6.1%; carbosulfan 27.0%, OR 5.7 (3.9–8.3); fenobucarb 18.9%, OR 3.6 (2.1–6.1)]. The clinical presentation and cause of death did not differ markedly between carbamates. Median time to death was similar: carbofuran 42.3 h (IQR 5.5–67.3), carbosulfan 21.3 h (11.5–71.3), and fenobucarb 25.3 h (17.3–72.1) (p = 0.99); no patients showed delayed onset of toxicity akin to the intermediate syndrome seen after OP insecticide poisoning. For survivors, median duration of intubation was 67.8 h (IQR 27.5–118.8) with no difference in duration between carbamates. Reduced GCS at presentation was associated with worse outcome although some patients with carbosulfan died after presentation with normal GCS. Conclusions: We did not find carbamate insecticide self-poisoning to vary markedly according to the carbamate

  5. Sex determination by SRY PCR and sequencing of Tasmanian devil facial tumour cell lines reveals non-allograft transmission.

    PubMed

    Cui, Xianlan; Wang, Yunfeng; Hua, Bobby; Miller, Webb; Zhao, Yan; Cui, Hongyu; Kong, Xiangang

    2016-05-20

    Devil facial tumour disease (DFTD) is an infectious tumour disease and was hypothesised to be transmitted by allograft during biting based on two cytogenetic findings of DFTD tumours in 2006. It was then believed that DFTD tumours were originally from a female devil. In this study the devil sex-determining region Y (SRY) gene was PCR amplified and sequenced, and six pairs of devil SRY PCR primers were used for detection of devil SRY gene fragments in purified DFTD tumour cell lines. Using three pairs of devil SRY PCR primers, devil SRY gene sequence was detected by PCR and sequencing in genomic DNA of DFTD tumour cell lines from six male devils, but not from six female devils. Four out of six DFTD tumour cell lines from male devils contained nucleotides 288-482 of the devil SRY gene, and another two DFTD tumour cell lines contained nucleotides 381-577 and 493-708 of the gene, respectively. These results indicate that the different portions of the SRY gene in the DFTD tumours of the male devils were originally from the male hosts, rejecting the currently believed DFTD allograft transmission theory. The reasons why DFTD transmission was incorrectly defined as allograft are discussed. PMID:27084454

  6. Comparative In silico Study of Sex-Determining Region Y (SRY) Protein Sequences Involved in Sex-Determining

    PubMed Central

    Vakili Azghandi, Masoume; Nasiri, Mohammadreza; Shamsa, Ali; Jalali, Mohsen; Shariati, Mohammad Mahdi

    2016-01-01

    Background: The SRY gene (SRY) provides instructions for making a transcription factor called the sex-determining region Y protein. The sex-determining region Y protein causes a fetus to develop as a male. In this study, SRY of 15 spices included of human, chimpanzee, dog, pig, rat, cattle, buffalo, goat, sheep, horse, zebra, frog, urial, dolphin and killer whale were used for determine of bioinformatic differences. Methods: Nucleotide sequences of SRY were retrieved from the NCBI databank. Bioinformatic analysis of SRY is done by CLC Main Workbench version 5.5 and ClustalW (http:/www.ebi.ac.uk/clustalw/) and MEGA6 softwares. Results: The multiple sequence alignment results indicated that SRY protein sequences from Orcinus orca (killer whale) and Tursiopsaduncus (dolphin) have least genetic distance of 0.33 in these 15 species and are 99.67% identical at the amino acid level. Homosapiens and Pantroglodytes (chimpanzee) have the next lowest genetic distance of 1.35 and are 98.65% identical at the amino acid level. Conclusion: These findings indicate that the SRY proteins are conserved in the 15 species, and their evolutionary relationships are similar. PMID:27536700

  7. Sex determination in platypus and echidna: autosomal location of SOX3 confirms the absence of SRY from monotremes.

    PubMed

    Wallis, M C; Waters, P D; Delbridge, M L; Kirby, P J; Pask, A J; Grützner, F; Rens, W; Ferguson-Smith, M A; Graves, J A M

    2007-01-01

    In eutherian ('placental') mammals, sex is determined by the presence or absence of the Y chromosome-borne gene SRY, which triggers testis determination. Marsupials also have a Y-borne SRY gene, implying that this mechanism is ancestral to therians, the SRY gene having diverged from its X-borne homologue SOX3 at least 180 million years ago. The rare exceptions have clearly lost and replaced the SRY mechanism recently. Other vertebrate classes have a variety of sex-determining mechanisms, but none shares the therian SRY-driven XX female:XY male system. In monotreme mammals (platypus and echidna), which branched from the therian lineage 210 million years ago, no orthologue of SRY has been found. In this study we show that its partner SOX3 is autosomal in platypus and echidna, mapping among human X chromosome orthologues to platypus chromosome 6, and to the homologous chromosome 16 in echidna. The autosomal localization of SOX3 in monotreme mammals, as well as non-mammal vertebrates, implies that SRY is absent in Prototheria and evolved later in the therian lineage 210-180 million years ago. Sex determination in platypus and echidna must therefore depend on another male-determining gene(s) on the Y chromosomes, or on the different dosage of a gene(s) on the X chromosomes. PMID:18185981

  8. Heavy metals in Ratnapura alluvial gem sediments, Sri Lanka

    NASA Astrophysics Data System (ADS)

    Vithanage, M. S.; Hettiarachchi, J. K.; Rajapaksha, A. U.; Wijesekara, H.; Hewawasam, T.

    2011-12-01

    The valuable gems in Sri Lanka are found from the sedimentary gem deposits in Ratnapura District, which are found as alluvial deposits some are about >50 m deep. Gem bearing gravel layer is taken out from the mine, washed by panning to recover the gem minerals in the heavy mineral fraction, is a common practice in the gem mining area. Gem bearing sediment layer is associated with different heavy minerals in which different trace metals as Co, Cr, Cu, Al, Zr, Pb and As also can be present. During panning, the sediment is washed away and the heavy metals attached to the sediments are released into the environment. Hence we studied the lability and bioavailability of arsenic and other heavy metals from the gem sediments. Sediment samples were collected from 15 small scale gem mines (3 soil layers- top, gem mineral layer and layer below gem bearing gravel layer), air dried and sieved to obtain <63μm fraction. Bioavailable, exchangeable and residual fractions were 0.01M CaCl2, 1M NaOAc, pH 8.2 and microwave digestion using HF, HNO3 and HClO4. Filtered samples were analyzed for As, Co, Zn, Mn, Cu, Ni, Pb and Fe using atomic absorption spectrophotometer (GBC 933AA). Total digestion results in different layers indicated that heavy metals show an increasing pattern with depth. About 4 gem bearing gravel layers were consist of high concentrations of Ni (>150 mg/kg), Cu (>150 mg/kg), Pb (>400 mg/kg), Zn (>600 mg/kg) and Co ions (>100 mg/kg). Arsenite in the gem sediments were low and recorded as <5mg/kg. Total arsenic analysis is under investigation. Highest concentrations for bioavailable and exchangeable (leach to water) metals were Fe>Co>Zn>Mn>Ni>Cu>Pb. Sediments from few gem pits showed considerably high concentrations of metals analyzed. In some places Fe, Ni, Cu, Zn reported high in bioavailable fractions 70, 25, 20, 10 mg/kg respectively. Mobilization of these metals may increase due to changes in the pH and the presence of other ions in the environment. High

  9. Women and Management in Higher Education. CHESS Workshop (Colombo, Sri Lanka, January 5-11, 1997).

    ERIC Educational Resources Information Center

    University Grants Commission (Sri Lanka).

    The Commonwealth Higher Education Support Scheme (CHESS) 1997 Workshop was designed to promote the professional development of women in leadership positions in higher education. Participants were drawn from senior university academics and administrators from five countries: Bangladesh, India, Malaysia, Pakistan, and Sri Lanka. Specific objectives…

  10. Dengue Virus Transmission by Blood Stem Cell Donor after Travel to Sri Lanka; Germany, 2013

    PubMed Central

    Punzel, Michael; Korukluoğlu, Gülay; Caglayik, Dilek Yagci; Menemenlioglu, Dilek; Bozdag, Sinem Civriz; Tekgündüz, Emre; Altuntaş, Fevzi; Campos, Renata de Mendonca; Burde, Bernd; Günther, Stephan; Tappe, Dennis; Cadar, Daniel

    2014-01-01

    Three days after donation of peripheral blood stem cells to a recipient with acute myeloblastic leukemia, dengue virus was detected in the donor, who had recently traveled to Sri Lanka. Transmission to the recipient, who died 9 days after transplant, was confirmed. PMID:25062084

  11. Lest the World Forget: Sri Lanka's Educational Needs after the 2004 Tsunami

    ERIC Educational Resources Information Center

    Cashman, Timothy G.; Asing-Cashman, Joyce G.

    2006-01-01

    This qualitative study strives to provide a greater understanding of the past, current, and future state of education in Sri Lanka after the 2004 tsunami. The researchers' key objectives are to provide additional insight to educators of the far-reaching impact of the tsunami via a website they created. Rather than concentrate on the same sort of…

  12. Grassroots Empowerment of Women: Portraits of Four Villages in Sri Lanka

    ERIC Educational Resources Information Center

    Jeris, Laurel; Gajanayake, Jaya; Ismail, Jesima; Ebert, Seela; Peris, Amara; Wanasundara, Leelangi; Diyadawagamage, Nalika

    2006-01-01

    This paper describes a participatory research (PR) project encompassing a capacity-development programme and advocacy skill-building initiative for rural women. The project actively engaged four prominent women's non-governmental organisations (NGOs) in Sri Lanka: Agromart Foundation, Centre for Women's Research (CENWOR), Sarvodaya Women's…

  13. Molecular mechanism of male differentiation is conserved in the SRY-absent mammal, Tokudaia osimensis

    PubMed Central

    Otake, Tomofumi; Kuroiwa, Asato

    2016-01-01

    The sex-determining gene SRY induces SOX9 expression in the testes of eutherian mammals via two pathways. SRY binds to testis-specific enhancer of Sox9 (TESCO) with SF1 to activate SOX9 transcription. SRY also up-regulates ER71 expression, and ER71 activates Sox9 transcription. After the initiation of testis differentiation, SOX9 enhances Amh expression by binding to its promoter with SF1. SOX8, SOX9 and SOX10, members of the SOXE gene family, also enhance the activities of the Amh promoter and TESCO. In this study, we investigated the regulation of these sexual differentiation genes in Tokudaia osimensis, which lacks a Y chromosome and the SRY gene. The activity of the AMH promoter was stimulated by SOXE genes and SF1. Mutant AMH promoters, with mutations in its SOX and SF1 binding sites, did not show significant activity by SOX9 and SF1. These results indicate that AMH expression was regulated by the binding of SOX9 and SF1. By contrast, SOXE genes could not enhance TESCO activity. These results indicate that TESCO enhancer activity was lost in this species. Furthermore, the activity of the SOX9 promoter was enhanced by ER71, indicating that ER71 may play an important role in the testis-specific expression of SOX9. PMID:27611740

  14. Distribution and ecological aspects of sand fly (Diptera: Psychodidae) species in Sri Lanka.

    PubMed

    Ozbel, Yusuf; Sanjoba, Chizu; Alten, Bulent; Asada, Masahito; Depaquit, Jerome; Matsumoto, Yasunobu; Demir, Samiye; Siyambalagoda, R R M L R; Rajapakse, R P V J; Matsumoto, Yoshitsugu

    2011-03-01

    Human indigenous cutaneous leishmaniasis caused by Leishmania donovani complex is endemic in Sri Lanka. We performed an entomological survey to determine the distribution of probable vector species. Sand flies were collected in districts in the dry zone, in the wet zone highlands, and in the wet zone coastal belt of Sri Lanka using CDC light traps, sticky traps and cattle-baited net traps during July, 2005. The survey was reconducted in February, 2006. Overall, 584 sand flies belonging to Phlebotomus (266 specimens, 2 species) and Sergentomyia (318 specimens, 8 species) genera were collected. A total of 266 Phlebotomus was identified as P. argentipes (258/266; 97%) and P. stantoni (8/266; 3%) . The identification studies of Sergentomyia specimens showed that there are at least 8 species in Sri Lanka. Higher number of Phlebotomus sand flies (76/266) were caught in the southern part of the country compared to the other parts probably due to different ecological aspects. P. argentipes were widely distributed throughout the island whereas P. stantoni were collected only in four districts. Since P. argentipes is known to be the vector of L. donovani responsible of visceral leishmaniasis in India, this species may be incriminated as the most possible vector of human cutaneous leishmaniasis in Sri Lanka. PMID:21366784

  15. Education Participation in Sri Lanka--Why All Are Not in School

    ERIC Educational Resources Information Center

    Arunatilake, Nisha

    2006-01-01

    Despite Sri Lanka's 1990 commitment to provide 10-11 years of free education to all, only 93% of children in the 5-14-year-old age group were in school by the year 2000. Moreover, the education participation rates are not equitable across the country, varying by socio-economic groups. This paper examines the determinants of school…

  16. Mass Communication in Sri Lanka: An Annotated Bibliography. Asian Mass Communication Bibliography Series 9.

    ERIC Educational Resources Information Center

    Goonetileke, H. A. I., Comp.; And Others

    Published and unpublished materials dealing with the multidisciplinary field of mass communication in Sri Lanka are listed in this bibliography. The 362 entries are grouped into 20 sections: bibliography and reference material; communication theory and research methods; general communication; media development and characteristics; newspapers;…

  17. Maternal employment and income affect dietary calorie adequacy in households in Sri Lanka.

    PubMed

    Rathnayake, Ishara M; Weerahewa, Jeevika

    2005-06-01

    Nutritional deficiencies among children and mothers in lower-income households in Sri Lanka continue to be a major obstacle to the country's social and economic development. This study investigates the factors affecting dietary caloric adequacy in Sri Lanka, paying special attention to maternal income. An econometric analysis was performed using a household data set collected from a sample of 183 low-income households in the urban, rural, and estate sectors. The results showed that on average, mothers and children in the sample did not consume adequate levels of calories according to the recommendations of the Medical Research Institute of Sri Lanka. The mother's income and educational status, the number of children and adults in the family, and the ages, sexes, and birth orders of the children significantly influenced household and individual caloric adequacy. Specifically, the mother's income had a significant positive effect on the total caloric intake (CI) and caloric adequacy ratio (CAR) of the household, mother, and children and a significant negative effect on the relative caloric allocation (RCA) of the children. The results imply that when maternal employment generates extra income, the CIs of all individuals increase, yet the allocation of calories to the children of the household is reduced. Thus, provision of employment opportunities for mothers, along with adequate child-care facilities and nutritional educational programs, is a possible strategy to improve caloric adequacy among low-income households in Sri Lanka. PMID:16060223

  18. Prevalence of Toxoplasma gondii in dogs from Sri Lanka and genetic characterization of the parasite isolates

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The prevalence of Toxoplasma gondii in 86 unwanted dogs obtained in two batches (36 in batch 1, 50 in batch 2) from Sri Lanka was determined. Antibodies to T. gondii were assayed by the modified agglutination test (MAT) and found in 58 (67.4%) of 86 dogs with titers of 1:20 in seven, 1:40 in four, ...

  19. Speaking Conflict: Ideological Barriers to Bilingual Policy Implementation in Civil War Sri Lanka

    ERIC Educational Resources Information Center

    Davis, Christina P.

    2015-01-01

    This article presents a holistic view of ideological barriers to bilingual policy implementation in Sri Lanka, a conflict-ridden postcolonial nation-state. I examine Sinhalese youth and adults' Tamil as a second language (TSL) learning and speaking practices across three contexts: a multilingual school, a program for government servants, and an…

  20. Mathematics Performance and Principal Effectiveness: A Case Study of Some Coastal Primary Schools in Sri Lanka

    ERIC Educational Resources Information Center

    Egodawatte, Gunawardena

    2012-01-01

    This mixed method research study is situated in the school effectiveness research paradigm to examine the correlation between the effectiveness of urban, primary school principals and their students' performance in mathematics. Nine, urban, primary schools from Negombo, a coastal fishing area in Sri Lanka, were selected; their student achievements…

  1. Deployable laboratory response to emergence of melioidosis in central Sri Lanka.

    PubMed

    Inglis, Timothy J J; Merritt, Adam; Montgomery, Joanne; Jayasinghe, Indika; Thevanesam, Vasanthi; McInnes, Russell

    2008-10-01

    A portable molecular diagnostic laboratory was used to provide molecular confirmation of suspected melioidosis cases seen at Peradeniya Hospital, central Sri Lanka. Soil supernatants from rice field and rubber plantation samples also produced PCR-positive results. These procedures could be used for melioidosis field work in other remote locations. PMID:18716231

  2. Molecular mechanism of male differentiation is conserved in the SRY-absent mammal, Tokudaia osimensis.

    PubMed

    Otake, Tomofumi; Kuroiwa, Asato

    2016-01-01

    The sex-determining gene SRY induces SOX9 expression in the testes of eutherian mammals via two pathways. SRY binds to testis-specific enhancer of Sox9 (TESCO) with SF1 to activate SOX9 transcription. SRY also up-regulates ER71 expression, and ER71 activates Sox9 transcription. After the initiation of testis differentiation, SOX9 enhances Amh expression by binding to its promoter with SF1. SOX8, SOX9 and SOX10, members of the SOXE gene family, also enhance the activities of the Amh promoter and TESCO. In this study, we investigated the regulation of these sexual differentiation genes in Tokudaia osimensis, which lacks a Y chromosome and the SRY gene. The activity of the AMH promoter was stimulated by SOXE genes and SF1. Mutant AMH promoters, with mutations in its SOX and SF1 binding sites, did not show significant activity by SOX9 and SF1. These results indicate that AMH expression was regulated by the binding of SOX9 and SF1. By contrast, SOXE genes could not enhance TESCO activity. These results indicate that TESCO enhancer activity was lost in this species. Furthermore, the activity of the SOX9 promoter was enhanced by ER71, indicating that ER71 may play an important role in the testis-specific expression of SOX9. PMID:27611740

  3. Feasibility of an appliance energy testing and labeling program for Sri Lanka

    SciTech Connect

    Biermayer, Peter; Busch, John; Hakim, Sajid; Turiel, Issac; du Pont, Peter; Stone, Chris

    2000-04-01

    A feasibility study evaluated the costs and benefits of establishing a program for testing, labeling and setting minimum efficiency standards for appliances and lighting in Sri Lanka. The feasibility study included: refrigerators, air-conditioners, flourescent lighting (ballasts & CFls), ceiling fans, motors, and televisions.

  4. Duty and Service: Life and Career of a Tamil Teacher of English in Sri Lanka

    ERIC Educational Resources Information Center

    Hayes, David

    2010-01-01

    This article discusses the life and career of a Tamil teacher of English working in the government education system in northern Sri Lanka. Based on data gathered in an extended life history interview, the article explores the teacher's own experiences of schooling, his reasons for entering teaching as a profession, his professional training, and…

  5. Atlas of Microorganisms in Coloured Rains and Meteorites in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Samaranayake, Anil; Wickramarathne, K.; Karunanayake, S. P. D.

    2013-02-01

    As a continuation of our earlier studies we present here an atlas of microscope images of organisms that we have discovered in a variety of coloured rain samples and meteorites that fell over Sri Lanka in December 2012 and January 2013.

  6. Financing and Educational Policy in Sri Lanka (Ceylon). Financing Educational Systems: Country Case Studies-1.

    ERIC Educational Resources Information Center

    Hallak, Jacques

    The retrospective case study presented is part of a research project undertaken to determine ways in which developing nations can best allocate resources to education in light of their social and economic levels. Past socioeconomic trends in Sri Lanka and its economy in the 1970's are considered first. The case study then moves into descriptions…

  7. Peace Education in Conflict Zones--Experience from Northern Sri Lanka

    ERIC Educational Resources Information Center

    Harris, Simon; Lewer, Nick

    2008-01-01

    In September 2005, adult students from Kilinochchi, located in the Liberation Tigers of Tamil Eelam (LTTE)-controlled Wanni region of northern Sri Lanka, were awarded University of Bradford, UK, validated postgraduate certificates or diplomas in conflict resolution and peace preparedness. The diploma is, we think, a landmark in peace education…

  8. Education Policy Reform in Sri Lanka: The Double-Edged Sword of Political Will

    ERIC Educational Resources Information Center

    Little, Angela W.

    2011-01-01

    In 1997, the Government of Sri Lanka launched a comprehensive set of education reforms designed to promote equitable access to basic education and improvements in learning outcomes. The package of reforms arose as a political response to widespread youth unrest in the late 1980s and attracted considerable "political will", a vague but much vaunted…

  9. Human Bocavirus in Patients with Encephalitis, Sri Lanka, 2009–2010

    PubMed Central

    Mori, Daisuke; Ranawaka, Udaya; Yamada, Kentaro; Rajindrajith, Shaman; Miya, Kazushi; Perera, Harsha Kumara Kithsiri; Matsumoto, Takashi; Dassanayake, Malka; Mitui, Marcelo Takahiro; Mori, Hisashi; Nishizono, Akira; Söderlund-Venermo, Maria

    2013-01-01

    We identified human bocavirus (HBoV) DNA by PCR in cerebrospinal fluid from adults and children with encephalitis in Sri Lanka. HBoV types 1, 2, and 3 were identified among these cases. Phylogenetic analysis of HBoV1 strain sequences found no subclustering with strains previously identified among encephalitis cases in Bangladesh. PMID:24188380

  10. Malaria Control and Elimination in Sri Lanka: Documenting Progress and Success Factors in a Conflict Setting

    PubMed Central

    Abeyasinghe, Rabindra R.; Galappaththy, Gawrie N. L.; Smith Gueye, Cara; Kahn, James G.; Feachem, Richard G. A.

    2012-01-01

    Background Sri Lanka has a long history of malaria control, and over the past decade has had dramatic declines in cases amid a national conflict. A case study of Sri Lanka's malaria programme was conducted to characterize the programme and explain recent progress. Methods The case study employed qualitative and quantitative methods. Data were collected from published and grey literature, district-level and national records, and thirty-three key informant interviews. Expenditures in two districts for two years – 2004 and 2009 – were compiled. Findings Malaria incidence in Sri Lanka has declined by 99.9% since 1999. During this time, there were increases in the proportion of malaria infections due to Plasmodium vivax, and the proportion of infections occurring in adult males. Indoor residual spraying and distribution of long-lasting insecticide-treated nets have likely contributed to the low transmission. Entomological surveillance was maintained. A strong passive case detection system captures infections and active case detection was introduced. When comparing conflict and non-conflict districts, vector control and surveillance measures were maintained in conflict areas, often with higher coverage reported in conflict districts. One of two districts in the study reported a 48% decline in malaria programme expenditure per person at risk from 2004 to 2009. The other district had stable malaria spending. Conclusions/Significance Malaria is now at low levels in Sri Lanka – 124 indigenous cases were found in 2011. The majority of infections occur in adult males and are due to P. vivax. Evidence-driven policy and an ability to adapt to new circumstances contributed to this decline. Malaria interventions were maintained in the conflict districts despite an ongoing war. Sri Lanka has set a goal of eliminating malaria by the end of 2014. Early identification and treatment of infections, especially imported ones, together with effective surveillance and response, will

  11. Twelve Years of Rabies Surveillance in Sri Lanka, 1999–2010

    PubMed Central

    Karunanayake, Dushantha; Matsumoto, Takashi; Wimalaratne, Omala; Nanayakkara, Susilakanthi; Perera, Devika; Nishizono, Akira; Ahmed, Kamruddin

    2014-01-01

    Background Rabies is endemic in Sri Lanka, but little is known about the temporal and spatial trends of rabies in this country. Knowing these trends may provide insight into past control efforts and serve as the basis for future control measures. In this study, we analyzed distribution of rabies in humans and animals over a period of 12 years in Sri Lanka. Methods Accumulated data from 1999 through 2010 compiled by the Department of Rabies Diagnosis and Research, Medical Research Institute (MRI), Colombo, were used in this study. Results The yearly mean percentage of rabies-positive sample was 62.4% (47.6–75.9%). Three-fourths of the rabies-positive samples were from the Colombo, Gampaha, and Kalutara districts in Western province, followed by Galle in Southern province. A high percentage of the rabies samples were from dogs (85.2%), followed by cats (7.9%), humans (3.8%), wild animals (2.0%), and livestock (1.1%). Among wild animals, mongooses were the main victims followed by civets. The number of suspect human rabies cases decreased gradually in Sri Lanka, although the number of human samples submitted for laboratory confirmation increased. Conclusions The number of rabid dogs has remained relatively unchanged, but the number of suspect human rabies is decreasing gradually in Sri Lanka. These findings indicate successful use of postexposure prophylaxis (PEP) by animal bite victims and increased rabies awareness. PEP is free of charge and is supplied through government hospitals by the Ministry of Health, Sri Lanka. Our survey shows that most positive samples were received from Western and Southern provinces, possibly because of the ease of transporting samples to the laboratory. Submissions of wild animal and livestock samples should be increased by creating more awareness among the public. Better rabies surveillance will require introduction of molecular methods for detection and the establishment of more regional rabies diagnostic laboratories. PMID:25299511

  12. Comparative Assessment of Irrigation Water Quality in Sri Lanka's Tank-Cascade and Mahaweli Irrigation Schemes

    NASA Astrophysics Data System (ADS)

    Gunda, T.; Hornberger, G. M.

    2013-12-01

    Two distinct irrigation systems dominate the landscape in the dry zone of Sri Lanka. The tank-cascade system, which originates from third century BC, is a small-scale system that has been the traditional method for communities to meet their farming water needs. The Mahaweli reservoir system, in contrast, is a large-scale irrigation scheme initiated in the 1970s that diverts water across hundreds of kilometers from the headwaters of the Mahaweli River to farmers. Although approximately equal amounts of paddy land are irrigated under these two systems, very little comparative analysis has been conducted on the spatial variation of irrigation water quality in Sri Lanka. An exploratory study was conducted in June 2013 in Anuradhapura district, an area that experiences the highest level of paddy production instability and has had long-standing irrigation water quality issues. A total of 30 water samples from both cascade systems and Mahaweli system H-7 were analyzed for pH, temperature, conductivity, turbidity, and chromatic dissolved organic matter using field instruments. A subset of these samples was further analyzed for nitrate and ammonia using colorimetric methods. While the sparse data from our study revealed some interesting trends, it is difficult to extrapolate in detail. Therefore, we compare inferences drawn about the Sri Lanka data to a more detailed analysis of chromatic dissolved organic matter in a Tennessee watershed. This comparison will provide insight into possible interpretations relative to the water quality data collected in Sri Lanka. As Sri Lanka continues to develop its irrigation resources, water quality assessments such as this one are critical for identifying factors limiting paddy production in the country.

  13. Does the linear Sry transcript function as a ceRNA for miR-138? The sense of antisense

    PubMed Central

    Granados-Riveron, Javier Tadeo; Aquino-Jarquin, Guillermo

    2014-01-01

    Recently, the sex determining region Y ( Sry) and the cerebellar degeneration-related protein 1 ( CDR1as) RNA transcripts have been described to function as a new class of post-transcriptional regulatory RNAs that behave as circular endogenous RNA sponges for the micro RNAs (miRNAs) miR-138 and miR-7, respectively. A special feature of the Sry gene is its ability to generate linear and circular transcripts, both transcribed in the sense orientation. Here we remark that both sense (e.g. Sry RNA) and antisense (e.g. CDR1as) transcripts could circularize and behave as miRNAs sponges, and importantly, that also protein-coding segments of mRNAs could also assume this role. Thus, it is reasonable to think that the linear Sry sense transcript could additionally act as a miRNA sponge, or as an endogenous competing RNA for miR-138. PMID:25580223

  14. A new canopy-dwelling species of Dendrelaphis (Serpentes: Colubridae) from Sinharaja, World Heritage Site, Sri Lanka.

    PubMed

    Wickramasinghe, L J Mendis

    2016-01-01

    A new species of Dendrelaphis, Dendrelaphis sinharajensis sp. nov. is described, the sixth species of the genus known from Sri Lanka. The new species is readily distinguished from all other congeners by its colour pattern and scalation. The species is a canopy-dweller known only from the Sinharaja World Heritage Site and its vicinity, in the lowland wet zone of Sri Lanka. PMID:27615987

  15. Integrated school-based surveillance for soil-transmitted helminth infections and lymphatic filariasis in Gampaha district, Sri Lanka.

    PubMed

    Gunawardena, Sharmini; Gunawardena, Nipul K; Kahathuduwa, Ganga; Karunaweera, Nadira D; de Silva, Nilanthi R; Ranasinghe, Udaya B; Samarasekara, Sandhya D; Nagodavithana, Kumara C; Rao, Ramakrishna U; Rebollo, Maria P; Weil, Gary J

    2014-04-01

    We explored the practicality of integrating surveillance for soil-transmitted helminthiasis (STH, assessed by Kato-Katz) with transmission assessment surveys for lymphatic filariasis (LF) in two evaluation units (EUs) in Gampaha district, Sri Lanka (population 2.3 million). The surveys were performed 6 years after five annual rounds of mass drug administration with diethylcarbamazine and albendazole. Each transmission assessment survey tested children (N = 1,462 inland EU; 1,642 coastal EU) sampled from 30 primary schools. Low filarial antigenemia rates (0% and 0.1% for the inland and coastal EUs) suggest that LF transmission is very low in this district. The STH rates and stool sample participation rates were 0.8% and 61% (inland) and 2.8% and 58% (coastal). Most STH detected were low or moderate intensity Trichuris trichiura infections. The added cost of including STH testing was ∼$5,000 per EU. These results suggest that it is feasible to integrate school-based surveillance for STH and LF. PMID:24493672

  16. Mapping Unhealthy Behavior Among Economically Active Men Using GIS in Suburban and Rural Areas of Sri Lanka.

    PubMed

    Silva, J Padmaka

    2016-01-01

    The burden of noncommunicable diseases (NCDs) and certain behavioral risk factors related to NCDs (unhealthy behaviors) are becoming more common. This survey aims to map out such common unhealthy behaviors among all men 35 to 50 years old in a Medical Officer of Health area in the Western Province of Sri Lanka using a geographical information system (GIS) and an interviewer administered questionnaire by visiting all households in the study area. Data were analyzed with ARC GIS and SPSS software. Geographical areas where men with unhealthy behaviors cluster together (clusters) were identified and visually and statistically related to locations of schools, places of religious worship, and factories in the area. It was revealed that clusters of unhealthy behaviors are mostly seen in areas with less population density. Smoking and alcohol are clustering in estate areas occupied by Tamils. This way GIS mapping could be used to identify and reduce the burden of NCDs by visualizing clusters and how certain locations affect their spread. PMID:26489433

  17. Complex network analysis of high rainfall events during the northeast monsoon over south peninsular India and Sri Lanka

    NASA Astrophysics Data System (ADS)

    Martin, P.; Malik, N.; Marwan, N.; Kurths, J.

    2012-04-01

    The Indian Summer monsoon (ISM) accounts for a large part of the annual rainfall budget across most of the Indian peninsula; however, the coastal regions along the southeast Indian peninsula, as well as Sri Lanka, receive 50% or more of their annual rainfall budget during the northeast monsoon (NEM), or winter monsoon, during the months from October through December. In this study, we investigate the behavior of the NEM over the last 60 years using complex network theory. The network is constructed according to a method previously developed for the ISM, using event synchronization of extreme rainfall events as a correlation measure to create directed and undirected links between geographical locations, which represent potential pathways of moisture transport. Network measures, such as degree centrality and closeness centrality, are then used to illuminate the dynamics of the NEM rainfall over the relevant regions, and to examine the spatial distribution and temporal evolution of the rainfall. Understanding the circulation of the monsoon cycle as a whole, i.e. the NEM together with the ISM, is vital for the agricultural industry and thus the population of the affected areas.

  18. Integrated School-Based Surveillance for Soil-Transmitted Helminth Infections and Lymphatic Filariasis in Gampaha District, Sri Lanka

    PubMed Central

    Gunawardena, Sharmini; Gunawardena, Nipul K.; Kahathuduwa, Ganga; Karunaweera, Nadira D.; de Silva, Nilanthi R.; Ranasinghe, Udaya B.; Samarasekara, Sandhya D.; Nagodavithana, Kumara C.; Rao, Ramakrishna U.; Rebollo, Maria P.; Weil, Gary J.

    2014-01-01

    We explored the practicality of integrating surveillance for soil-transmitted helminthiasis (STH, assessed by Kato-Katz) with transmission assessment surveys for lymphatic filariasis (LF) in two evaluation units (EUs) in Gampaha district, Sri Lanka (population 2.3 million). The surveys were performed 6 years after five annual rounds of mass drug administration with diethylcarbamazine and albendazole. Each transmission assessment survey tested children (N = 1,462 inland EU; 1,642 coastal EU) sampled from 30 primary schools. Low filarial antigenemia rates (0% and 0.1% for the inland and coastal EUs) suggest that LF transmission is very low in this district. The STH rates and stool sample participation rates were 0.8% and 61% (inland) and 2.8% and 58% (coastal). Most STH detected were low or moderate intensity Trichuris trichiura infections. The added cost of including STH testing was ∼$5,000 per EU. These results suggest that it is feasible to integrate school-based surveillance for STH and LF. PMID:24493672

  19. Mapping Unhealthy Behavior Among Economically Active Men Using GIS in Suburban and Rural Areas of Sri Lanka

    PubMed Central

    Silva, J Padmaka; Gunathunga, M W; Jayasinghe, S

    2016-01-01

    The burden of noncommunicable diseases (NCDs) and certain behavioral risk factors related to NCDs (unhealthy behaviors) are becoming more common. This survey aims to map out such common unhealthy behaviors among all men 35 to 50 years old in a Medical Officer of Health area in the Western Province of Sri Lanka using a geographical information system (GIS) and an interviewer administered questionnaire by visiting all households in the study area. Data were analyzed with ARC GIS and SPSS software. Geographical areas where men with unhealthy behaviors cluster together (clusters) were identified and visually and statistically related to locations of schools, places of religious worship, and factories in the area. It was revealed that clusters of unhealthy behaviors are mostly seen in areas with less population density. Smoking and alcohol are clustering in estate areas occupied by Tamils. This way GIS mapping could be used to identify and reduce the burden of NCDs by visualizing clusters and how certain locations affect their spread. PMID:26489433

  20. Cascade Screening for Fragile X Syndrome/CGG Repeat Expansions in Children Attending Special Education in Sri Lanka

    PubMed Central

    Chong, Samuel S.; Rajan-Babu, Indhu-Shree

    2015-01-01

    Fragile X syndrome (FXS) is the commonest cause of inherited mental retardation and clinically presents with learning, emotional and behaviour problems. FXS is caused by expansion of cytosine-guanine-guanine (CGG) repeats present in the 5’ untranslated region of the FMR1 gene. The aim of this study was to screen children attending special education institutions in Sri Lanka to estimate the prevalence of CGG repeat expansions. The study population comprised a representative national sample of 850 children (540 males, 310 females) with 5 to 18 years of age from moderate to severe mental retardation of wide ranging aetiology. Screening for CGG repeat expansion was carried out on DNA extracted from buccal cells using 3’ direct triplet primed PCR followed by melting curve analysis. To identify the expanded status of screened positive samples, capillary electrophoresis, methylation specific PCR and Southern hybridization were carried out using venous blood samples. Prevalence of CGG repeat expansions was 2.2%. Further classification of the positive samples into FXS full mutation, pre-mutation and grey zone gave prevalence of 1.3%, 0.8% and 0.1% respectively. All positive cases were male. No females with FXS were detected in our study may have been due to the small sample size. PMID:26694146

  1. Description of a new species of rabbitfish (Perciformes: Siganidae) from southern India, Sri Lanka and the Maldives.

    PubMed

    Woodland, David J; Anderson, R Charles

    2014-01-01

    Siganus insomnis sp. nov. is described from the Maldives, Sri Lanka and southern India. It most closely resembles S. lineatus (Valenciennes) from the Western Pacific but differs in coloration, principally in that most if not all of the bronze bands on its mid and upper sides continue horizontally and unbroken through to the nape and opercular slit. By contrast, in S. lineatus, typically the anterior area below the spinous dorsal fin down to the mid-sides is irregularly marked with golden bronze spots, commas, or a maze of contorted lines. S. guttatus (Bloch) is the third member of this group of sibling species; its sides are covered with orange to bronze-gold spots. It is distributed throughout S.E. Asia, i.e., it occupies a geographic position between the areas inhabited by S. lineatus and S. insomnis. Thus the gene pools of S. lineatus and S. insomnis are quarantined from one another by distance and the intervening presence of S. guttatus in S.E. Asia. The geographical separation of the populations of S. lineatus and S. insomnis from one another is reinforced by the absence of suitable, coralline habitats for these species in the western half of the Bay of Bengal.  PMID:24943153

  2. Cross-Sectional Study to Assess Risk Factors for Leishmaniasis in an Endemic Region in Sri Lanka

    PubMed Central

    Ranasinghe, Shalindra; Wickremasinghe, Rajitha; Munasinghe, Asoka; Hulangamuwa, Sanjeeva; Sivanantharajah, Sundaramoorthy; Seneviratne, Kamal; Bandara, Samantha; Athauda, Indira; Navaratne, Chaturi; Silva, Ositha; Wackwella, Hasini; Matlashewski, Greg; Wickremasinghe, Renu

    2013-01-01

    Sri Lanka reports significantly more cutaneous leishmaniasis (CL) cases than visceral leishmaniasis (VL) cases, both of which are caused by Leishmania donovani MON-37. A cross-sectional study conducted in an area with a high prevalence of CL prevalent included 954 participants of an estimated population of 61,674 to estimate the number of CL cases, ascertain whether there is a pool of asymptomatic VL cases, and identify risk factors for transmission. A total of 31 cases of CL were identified, of whom 21 were previously diagnosed and 10 were new cases. Using rK39 rapid diagnostic test to detect antibodies against Leishmania spp., we found that only one person was seropositive but did not have clinical symptoms of CL or VL, which indicated low transmission of VL in this area. χ2 test, independent sample t-test, and multivariate analysis of sociodemographic and spatial distribution of environmental risk factors showed that living near paddy fields is associated with increased risk for transmission of CL (P ≤ 0.01). PMID:23918217

  3. Population education in the schools.

    PubMed

    Sherris, J D; Quillin, W F

    1982-01-01

    Formal population education is designed to teach children in school about basic population issues and, in many cases, to encourage them eventually to have smaller families. Some programs include specific units on human reproduction and family planning, while others do not. National population education programs began during the 1970s in about a dozen countries, mainly in Asia. These include Bangladesh, India, Indonesia, South Korea, Malaysia, the Philippines, Sierra Leone, Sri Lanka, Singapore, Thailand, Egypt, Tunisia, and El Salvador. A strong case can be made for including an important contemporary issue like population in the school curriculum. Nevertheless, educational innovation is a difficult and long-term process. As a rule, it takes 5 to 10 years before new material can be fully incorporated in a school curriculum. Curriculum changes must be carefully planned, thousands of teachers trained, and appropriate materials prepared for classroom use. Moreover, differences of opinion over the need, acceptability, goals, content, methods, and other aspects of population education have held back programs in some countries. Where population education programs have been implemented, student knowledge of population issues increases, but it is not yet clear whether in-school education has a measurable impact on fertility-related attitudes or behavior. PMID:7043518

  4. Patterns of hospital transfer for self-poisoned patients in rural Sri Lanka: implications for estimating the incidence of self-poisoning in the developing world.

    PubMed Central

    Eddleston, Michael; Sudarshan, K.; Senthilkumaran, M.; Reginald, K.; Karalliedde, Lakshman; Senarathna, Lalith; de Silva, Dhammika; Rezvi Sheriff, M. H.; Buckley, Nick A.; Gunnell, David

    2006-01-01

    OBJECTIVES: Most data on self-poisoning in rural Asia have come from secondary hospitals. We aimed to: assess how transfers from primary to secondary hospitals affected estimates of case-fatality ratio (CFR); determine whether there was referral bias according to gender or poison; and estimate the annual incidence of all self-poisoning, and of fatal self-poisoning, in a rural developing-world setting. METHODS: Self-poisoning patients admitted to Anuradhapura General Hospital, Sri Lanka, were reviewed on admission from 1 July to 31 December 2002. We audited medical notes of self-poisoning patients admitted to 17 of the 34 surrounding peripheral hospitals for the same period. FINDINGS: A total of 742 patients were admitted with self-poisoning to the secondary hospital; 81 died (CFR 10.9%). 483 patients were admitted to 17 surrounding peripheral hospitals. Six patients (1.2%) died in peripheral hospitals, 249 were discharged home, and 228 were transferred to the secondary hospital. There was no effect of gender or age on likelihood of transfer; however, patients who had ingested oleander or paraquat were more likely to be transferred than were patients who had taken organophosphorus pesticides or other poisons. Estimated annual incidences of self-poisoning and fatal self-poisoning were 363 and 27 per 100,000 population, respectively, with an overall CFR of 7.4% (95% confidence interval 6.0-9.0). CONCLUSION: Fifty per cent of patients admitted to peripheral hospitals were discharged home, showing that CFRs based on secondary hospital data are inflated. However, while incidence of self-poisoning is similar to that in England, fatal self-poisoning is three times more common in Sri Lanka than fatal self-harm by all methods in England. Population based data are essential for making international comparisons of case fatality and incidence, and for assessing public health interventions. PMID:16628300

  5. A hazards-model analysis of the covariates of infant and child mortality in Sri Lanka.

    PubMed

    Trussell, J; Hammerslough, C

    1983-02-01

    The purpose of this paper is twofold: (a) to provide a complete self-contained exposition of estimating life tables with covariates through the use of hazards models, and (b) to illustrate this technique with a substantive analysis of child mortality in Sri Lanka, thereby demonstrating that World Fertility Survey data are a valuable source for the study of child mortality. We show that life tables with covariates can be easily estimated with standard computer packages designed for analysis of contingency tables. The substantive analysis confirms and supplements an earlier study of infant and child mortality in Sri Lanka by Meegama. Those factors found to be strongly associated with mortality are mother's and father's education, time period of birth, urban/rural/estate residence, ethnicity, sex, birth order, age of the mother at the birth, and type of toilet facility. PMID:6832431

  6. Groundwater overuse and farm-level technical inefficiency: evidence from Sri Lanka

    NASA Astrophysics Data System (ADS)

    Athukorala, Wasantha; Wilson, Clevo

    2012-08-01

    Extraction of groundwater for onion and other cash crop production has been increasing rapidly during the last two decades in the dry zone areas of Sri Lanka. As a result of overuse, the quantity of available groundwater is gradually declining, while water quality is deteriorating. The deteriorating water quality has a negative impact on agricultural production, especially for crops (such as onions) that are sensitive to increases in salinity levels. This issue is examined with respect to onion production in Sri Lanka. A stochastic frontier production function (SFPF) is used, in which technical efficiency and the determinants of inefficiencies are estimated simultaneously. The results show that farmers are overusing groundwater in their onion cultivation, which has resulted in decreasing yields. Factors contributing to inefficiency in production are also identified. The results have important policy implications.

  7. Sri Lanka field survey after the December 2004 Indian Ocean tsunami

    USGS Publications Warehouse

    Goff, James; Liu, Philip L-F.; Higman, Bretwood; Morton, Robert; Jaffe, Bruce E.; Fernando, Haindra; Lynett, Patrick; Fritz, Hermann; Synolakis, Costas; Fernando, Starin

    2006-01-01

    An International Tsunami Survey Team (ITST) consisting of scientists from the United States, New Zealand, and Sri Lanka evaluated the impacts of the 26 December 2004 transoceanic tsunami in Sri Lanka two weeks after the event. Tsunami runup height, inundation distance, morphological changes, and sedimentary characteristics of deposits were recorded and analyzed along the southwest and east coasts of the country. Preliminary results show how local topography and bathymetry controlled the limits of inundation and associated damage to the infrastructure. The largest wave height of 8.71 m was recorded at Nonagama, while the greatest inundation distance of 390 m and runup height of 12.50 m was at Yala. At some sites, human alterations to the landscape increased the damage caused by the tsunami; this was particularly evident in areas of coral poaching and of sand dune removal.

  8. Detection of variant infectious bronchitis viruses in Sri Lanka (2012-2015).

    PubMed

    Ball, Christopher; Forrester, Anne; Ganapathy, Kannan

    2016-06-01

    Poultry production is an important sector of agriculture in Sri Lanka; however, there is a lack of information regarding circulation of infectious bronchitis virus (IBV). RNA was extracted from chicken tissues, subjected to IBV S1 RT-PCR, and sequenced. Overall, 19 out of 34 (55.88 %) samples were IBV positive and contained the genotype 793B (n = 13; 68.42 %), D274 (n = 4; 21.05 %) or Massachusetts (n = 2; 10.53 %). All three genotypes contained at least one strain with less than 99 % nucleotide sequence identity to the corresponding vaccine strains. This report identified co-circulation of IBV strains 793B, Massachusetts and D274, in Sri Lanka that are divergent from the respective vaccine strains. PMID:27020570

  9. Non-fatal self-poisoning across age groups, in Sri Lanka.

    PubMed

    Rajapakse, Thilini; Christensen, Helen; Cotton, Sue; Griffiths, Kathleen Margaret

    2016-02-01

    Attempted or non-fatal self-poisoning in common in Sri Lanka, but little is known about variation of psychiatric morbidity and suicidal intent across differing ages. The aim of this study was to investigate factors associated with non-fatal self-poisoning in Sri Lanka across three different age groups (namely 14-24 years, 25-34 years and ≥35 years). It was anticipated that the findings of the study would inform and guide development of preventive interventions for non-fatal self-poisoning in this country. 935 participants were interviewed within one week of admission to hospital for medical management of non-fatal self-poisoning, over a consecutive 14-month period. Socio-demographic factors, types of poison ingested, triggers and psychiatric morbidity was examined as a function of age. Results showed that a majority (83%) of participants were aged below 35 years. Younger participants aged <25 years were significantly more likely to ingest medicinal overdoses, compared to older persons (aged 25-34 years, and ≥35 years), who were more likely to ingest pesticides. Recent interpersonal conflict was a proximal trigger seen in all age groups, but suicidal intent, depression and alcohol use disorders increased with age. The overall study findings indicate that most who carry out acts of non-fatal self-poisoning in Sri Lanka are young (aged <35 years). Interpersonal conflict as a trigger is common to all age groups, but psychiatric morbidity and suicidal intent is higher in the older age groups, as is pesticide ingestion. Age specific interventions may be efficacious in the prevention of non-fatal self-poisoning in Sri Lanka. PMID:26957344

  10. Assessment of the SRI Gasification Process for Syngas Generation with HTGR Integration -- White Paper

    SciTech Connect

    A.M. Gandrik

    2012-04-01

    This white paper is intended to compare the technical and economic feasibility of syngas generation using the SRI gasification process coupled to several high-temperature gas-cooled reactors (HTGRs) with more traditional HTGR-integrated syngas generation techniques, including: (1) Gasification with high-temperature steam electrolysis (HTSE); (2) Steam methane reforming (SMR); and (3) Gasification with SMR with and without CO2 sequestration.

  11. PREFACE: 17th Pan-American Synchrotron Radiation Instrumentation Conference SRI2013

    NASA Astrophysics Data System (ADS)

    Williams, Gwyn P.; Revesz, Peter; Arp, Uwe

    2014-03-01

    These proceedings are a collection of the articles presented at the seventeenth Pan-American Synchrotron Radiation Instrumentation Conference SRI2013, held on the campus of the National Institute of Standards and Technology (NIST), located in Gaithersburg, Maryland, United States of America, 19-21 June, 2013. SRI2013 was jointly hosted by the Cornell University Cornell High Energy Synchrotron Source (CHESS), the Thomas Jefferson National Accelerator Facility (Jefferson Lab), and the Synchrotron Ultraviolet Radiation Facility (SURF III) at NIST. This meeting's focus was clearly on instrumentation, thus fulfilling the intent of this SRI meeting series, which was initiated at NIST, then the National Bureau of Standards (NBS), in 1979. SRI2013 hosted more than 150 delegates, despite the new US governmental travel restrictions. This proceedings series aims to be an essential reference work for practitioners in the field. It primarily documents the evolution and development of techniques, but also recent scientific advances, that were presented during the two and a half days of the conference. We are extremely thankful to all the authors who contributed to making these proceedings a volume of reference as well as to the reviewers for their careful reading and constructive recommendations for improving the articles. Great thanks go to Robert Dragoset at NIST, for creating and maintaining the conference website and generating the conference logo. We are also thankful for the excellent support we received from the Conference Program at NIST, especially Kathy Kilmer and Angela Ellis. And we would like to dedicate these proceedings to the memory of Kathy Kilmer, who passed away on 15 October, 2013. NIST will not be the same without her. The Co-Editors: Uwe Arp (SURF/NIST) Peter Reversz (CHESS) Gwyn P Williams (Jefferson Lab)

  12. Developing tools to link environmental flows science and its practice in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Eriyagma, N.; Jinapala, K.

    2014-09-01

    The term "Environmental Flows (EF)" may be defined as "the quantity, timing and quality of water flows required to sustain freshwater and estuarine ecosystems and the human livelihoods and well-being that depend on these ecosystems". It may be regarded as "water for nature" or "environmental demand" similar to crop water requirements, industrial or domestic water demand. The practice of EF is still limited to a few developed countries such as Australia, South Africa and the UK. In many developing countries EF is rarely considered in water resources planning and is often deemed "unimportant". Sri Lanka, being a developing country, is no exception to this general rule. Although the country underwent an extensive irrigation/water resources development phase during the 1960s through to the 1980s, the concept of EF was hardly considered. However, as Sri Lanka's water resources are being exploited more and more for human usage, ecologists, water practitioners and policymakers alike have realized the importance of EF in sustaining not only freshwater and estuarine ecosystems, but also their services to humans. Hence estimation of EF has been made mandatory in environmental impact assessments (EIAs) of all large development projects involving river regulation/water abstraction. Considering EF is especially vital under the rapid urbanization and infrastructure development phase that dawned after the end of the war in the North and the East of the country in 2009. This paper details simple tools (including a software package which is under development) and methods that may be used for coarse scale estimation of EF at/near monitored locations on major rivers of Sri Lanka, along with example applications to two locations on River Mahaweli. It is hoped that these tools will help bridge the gap between EF science and its practice in Sri Lanka and other developing countries.

  13. Dehydration and malaria augment the risk of developing chronic kidney disease in Sri Lanka

    PubMed Central

    Siriwardhana, E. A. R. I. E.; Perera, P. A. J.; Sivakanesan, R.; Abeysekara, T.; Nugegoda, D. B.; Jayaweera, J. A. A. S.

    2015-01-01

    Chronic kidney disease (CKD) of unknown etiology (CKDu) is a serious health issue in Sri Lanka. One-to-one age and sex-matched two sample comparative study was carried out in the Medawachchiya divisional secretariat area of the North Central Province (NCP) of Sri Lanka, by randomly selecting 100 CKDu patients and 100 age and sex-matched subjects from non-CKDu affected families from the same area. An interviewer-administered questionnaire was used for the collection of data pertaining to occupation, medical history and lifestyle. Data were analyzed using a conditional linear logistic model. Working for >6 h in the field per day, exposure to sun, drinking water only from well, consumption of <3 L of water per day, and having a history of malaria were found to be having significant (P < 0.05) likelihood toward the development of CKDu. Treatment of water prior to consumption had a significant protective effect against CKDu. Dehydration, history of malaria and drinking untreated well water from are likely contribute to the development of CKD of unknown etiology among the inhabitants of NCP, Sri Lanka. PMID:26060363

  14. Resistance Towards the Language of Globalisation - The Case of Sri Lanka

    NASA Astrophysics Data System (ADS)

    Punchi, Lakshman

    2001-07-01

    This paper relates the contemporary educational reforms in Sri Lanka to the processes of globalisation. The international monetary organisations such as the IMF and the World Bank and the regional organisations like the Asian Development Bank (ADB) play a dominant role in influencing the debt-receiving countries when it comes to their educational practice. The intensity of the influence of these organisations can vary depending on the existing educational policy of the aid receiving countries. This paper, after a brief introduction on globalisation, examines its effects on the education policy in Sri Lanka with a special emphasis on the current language policy. Equity in education is usually advocated at primary level based on the universal primary education concept so highly upheld by the World Bank. However, the present high human development indicators are undoubtedly due to Sri Lanka's free education policy in native languages. The paper concludes stressing the importance to retain the national education policy as a means of empowerment and liberation of its masses and creating stronger ethnic harmony.

  15. Occupational risk factors for low back pain among drivers of three-wheelers in Sri Lanka

    PubMed Central

    Noda, Misa; Malhotra, Rahul; DeSilva, Vijitha; Sapukotana, Pasindu; DeSilva, Asela; Kirkorowicz, Jacob; Allen, John; Østbye, Truls

    2015-01-01

    Background: Approximately 5% of all households in Sri Lanka operate a three-wheeler as their primary source of income. However, very little is known about the occupational health risks associated with driving these vehicles. Objectives: The aim of this study was to assess occupational risk factors, including the number of hours worked associated with the 4-week prevalence of low back pain (LBP) among drivers of three-wheelers. Methods: Questionnaires were administered to 200 full-time drivers of three-wheelers from the Galle District in Sri Lanka. Occupational, psychological, socio-demographic, lifestyle, and anthropometric variables were collected. Univariate and multivariate analysis were used to investigate the correlation between occupational risk factors of the prevalence of LBP. Results: 15.5% of respondents reported experiencing LBP in the previous 4 months. Univariate analysis revealed that the number of hours worked per week, feeling pressure to compete with other drivers, and perceived stress scale scores were significantly associated with the 4-week prevalence of LBP. Multivariate analysis found that the number of hours worked per week and engine type were significantly associated with LBP. Conclusions: LBP is common among drivers of three-wheelers in Sri Lanka. Long work hours and two-stroke engines were significantly associated with LBP. Results from this study point towards a role for educational, behavioral health, and policy interventions to help prevent and reduce LBP among these drivers. PMID:25133353

  16. Disorder of sexual development in a Yorkshire terrier (78, XY; SRY-positive).

    PubMed

    Dianovský, Ján; Holečková, Beáta; Hajurka, Jaroslav; Šiviková, Katarina; Cigánková, Viera

    2013-05-01

    A 9-month-old Yorkshire terrier was admitted to the clinic because of abnormal sexual behaviour and clitoral hypertrophy. External examination confirmed standard development of caudal genital organs: vagina, vulva and cervix uteri. Serum profile of gonadotropin hormones 17 β-estradiol (<10.0 pg.ml(-1)) and testosterone (9.1 ng.ml(-1)) revealed the presence of testicular tissue. A midline laparotomy was performed to detect the cranial parts of the genital system. Gonads resembling testicles, structures indicating epididymis and rudimentary deferent ducts were resected, along with adherent part of the uterus. Cytogenetic analysis showed a male chromosomal complement 78, XY in all metaphases of the studied Yorkshire terrier dog. The chromosomal constitution was confirmed by fluorescence in situ hybridisation (FISH) with whole-chromosome painting probes specific for chromosomes X and Y, as well as by polymerase chain reaction (PCR) amplification of the 271-bp Y-linked fragment of SRY (the sex-determining region on the Y chromosome) gene. Sequencing of the dog's SRY gene coding region did not reveal any mutation. To search for potential mutation in the SOX9 gene (Sry-box containing gene 9), which is considered to be one of the key genes involved in the sex determination process, the PCR fragments of exons 1, 2 and 3 originating from the canine patient were sequenced in order to compare with both male and female healthy control dogs. In the analysed regions of the SOX9 gene, no mutation was found. PMID:23378246

  17. Application of Modis Data to Assess the Latest Forest Cover Changes of Sri Lanka

    NASA Astrophysics Data System (ADS)

    Perera, K.; Herath, S.; Apan, A.; Tateishi, R.

    2012-07-01

    Assessing forest cover of Sri Lanka is becoming important to lower the pressure on forest lands as well as man-elephant conflicts. Furthermore, the land access to north-east Sri Lanka after the end of 30 years long civil war has increased the need of regularly updated land cover information for proper planning. This study produced an assessment of the forest cover of Sri Lanka using two satellite data based maps within 23 years of time span. For the old forest cover map, the study used one of the first island-wide digital land cover classification produced by the main author in 1988. The old land cover classification was produced at 80 m spatial resolution, using Landsat MSS data. A previously published another study by the author has investigated the application feasibility of MODIS and Landsat MSS imagery for a selected sub-section of Sri Lanka to identify the forest cover changes. Through the light of these two studies, the assessment was conducted to investigate the application possibility of MODIS 250 m over a small island like Sri Lanka. The relation between the definition of forest in the study and spatial resolution of the used satellite data sets were considered since the 2012 map was based on MODIS data. The forest cover map of 1988 was interpolated into 250 m spatial resolution to integrate with the GIS data base. The results demonstrated the advantages as well as disadvantages of MODIS data in a study at this scale. The successful monitoring of forest is largely depending on the possibility to update the field conditions at regular basis. Freely available MODIS data provides a very valuable set of information of relatively large green patches on the ground at relatively real-time basis. Based on the changes of forest cover from 1988 to 2012, the study recommends the use of MODIS data as a resalable method to forest assessment and to identify hotspots to be re-investigated. It's noteworthy to mention the possibility of uncounted small isolated pockets of

  18. Testicular disorder of sex development in four cats with a male karyotype (38,XY; SRY-positive).

    PubMed

    Nowacka-Woszuk, Joanna; Szczerbal, Izabela; Salamon, Sylwia; Kociucka, Beata; Jackowiak, Hanna; Prozorowska, Ewelina; Slaska, Brygida; Rozanska, Dorota; Orzelski, Maciej; Ochota, Malgorzata; Dzimira, Stanislaw; Lipiec, Magdalena; Nizanski, Wojciech; Switonski, Marek

    2014-12-10

    The molecular background of disorders of sex development (DSD) in cats is poorly recognized. In this study we present cytogenetic, molecular and histological analyses of four cats subjected for the analysis due to ambiguous external genitalia. Three cases, with rudimentary penises and an abnormal position of the urethral orifice, represented different types of hypospadias. The fourth case had a normal penis, a blind vulva and spermatogenetically active testes. Histological studies showed structures typical of testes, but spermatogenic activity was observed in two cats only. All the cats had a normal male chromosome complement (38,XY) and the Y-chromosome linked genes (SRY and ZFY) were also detected. Fluorescent in situ hybridization (FISH), with the use of the feline BAC probe harboring the SRY gene, excluded the possibility of chromosome translocation of the Y chromosome fragment carrying the SRY gene onto another chromosome. Sequencing of four candidate genes (SRY--sex determining region Y; AR--androgen receptor; SRD5A2--steroid-5-alfa reductase 2 and MAMLD1--mastermind-like domain containing (1) revealed one SNP in the SRY gene, one common polymorphism in exon 1 of the AR gene (tandem repeat of a tri-nucleotide motif--CAG), six polymorphisms (5 SNPs and 1 indel) in the SRD5A2 gene and one SNP in the MAMLD1 gene. Molecular studies of the candidate genes showed no association with the identified polymorphisms, thus molecular background of the studied DSD phenotypes remains unknown. PMID:25455261

  19. The Pearl of Great Price: Achieving Equitable Access to Primary and Secondary Education and Enhancing Learning in Sri Lanka. CREATE Pathways to Access. Research Monograph No. 29

    ERIC Educational Resources Information Center

    Aturupane, Harsha

    2009-01-01

    The experience of public policy in Sri Lanka has had a profound impact on the thinking of the global development community in relation to the role of education in economic development. In particular, the example of Sri Lanka helped to persuade policy makers around the world that governments can successfully develop a general education system to…

  20. Early Effects of a ‘Train the Trainer’ Approach to Ponseti Method Dissemination: A Case Study of Sri Lanka

    PubMed Central

    Jayawardena, Asitha; Wijayasinghe, Sunil R.; Tennakoon, Dimuthu; Cook, Thomas; Morcuende, Jose A.

    2013-01-01

    Background The Ponseti method has been established as the standard of care for the treatment of clubfoot in many developed countries for its utility, cost-effectiveness, and efficiency. However, despite its being described as the gold-standard for clubfoot treatment, there are still many areas of the world bereft in formal training in the Ponseti method. This is especially important since 80% of patients with clubfoot are born in developing countries where the need is the greater for experienced providers. This study analyzes a ‘Train the Trainer’ approach, specifically in the island nation of SriLanka, as a model for future dissemination of the Ponseti method throughout the developing world. Methods A rapid ethnographic study design that included interviews, focus groups, and direct observation of 162 patients and healthcare practitioners directly involved with clubfoot care was conducted. Results The average age of the patients at the time of the interview was 75.4 weeks old (SD = 149.2), traveled 45.2 kilometers (SD = 49.8) to receive their care, and received 4 casts (SD = 2.2) for correction of the deformity. Since the initiation of the ‘Train the Trainer’ educational program, clubfoot clinics reportedly grew from 6-7 patients per week to over 60 patients per week. The majority of this patient population growth was attributed to word of mouth. Major barriers to the method included casting materials, bracing materials, and a lack of a dedicated area of the clinic to conduct tenotomies under local anesthesia. Of note, cost was not cited as a major barrier. Conclusion Early evaluation suggests great utility of the ‘Train the Trainer’ method – especially regarding an increased patient demand for treatment. However, further studies are necessary to understand the long-term utility of this training methodology. PMID:24027476

  1. The correlation between dengue incidence and diurnal ranges of temperature of Colombo district, Sri Lanka 2005–2014

    PubMed Central

    Ehelepola, N. D. B.; Ariyaratne, Kusalika

    2016-01-01

    Background Meteorological factors affect dengue transmission. Mechanisms of the way in which different diurnal temperatures, ranging around different mean temperatures, influence dengue transmission were published after 2011. Objective We endeavored to determine the correlation between dengue incidence and diurnal temperature ranges (DTRs) in Colombo district, Sri Lanka, and to explore the possibilities of using our findings to improve control of dengue. Design We calculated the weekly dengue incidence in Colombo during 2005–2014, after data on all of the reported dengue patients and estimated mid-year populations were collected. We obtained daily maximum and minimum temperatures from two Colombo weather stations, averaged, and converted them into weekly data. Weekly averages of DTR versus dengue incidence graphs were plotted and correlations observed. The count of days per week with a DTR of >7.5°C and <7.5°C were also calculated. Wavelet time series analysis was performed to determine the correlation between dengue incidence and DTR. Results We obtained a negative correlation between dengue incidence and a DTR>7.5°C with an 8-week lag period, and a positive correlation between dengue incidence and a DTR<7.5°C, also with an 8-week lag. Conclusions Large DTRs were negatively correlated with dengue transmission in Colombo district. We propose to take advantage of that in local dengue control efforts. Our results agree with previous studies on the topic and with a mathematical model of relative vectorial capacity of Aedes aegypti. Global warming and declining DTR are likely to favor a rise of dengue, and we suggest a simple method to mitigate this. PMID:27566717

  2. Disorders of Sex Development with Testicular Differentiation in SRY-Negative 46,XX Individuals: Clinical and Genetic Aspects.

    PubMed

    Grinspon, Romina P; Rey, Rodolfo A

    2016-01-01

    Virilisation of the XX foetus is the result of androgen excess, resulting most frequently from congenital adrenal hyperplasia in individuals with typical ovarian differentiation. In rare cases, 46,XX gonads may differentiate into testes, a condition known as 46,XX testicular disorders of sex development (DSD), or give rise to the coexistence of ovarian and testicular tissue, a condition known as 46,XX ovotesticular DSD. Testicular tissue differentiation may be due to the translocation of SRY to the X chromosome or an autosome. In the absence of SRY, overexpression of other pro-testis genes, e.g. SOX family genes, or failure of pro-ovarian/anti-testis genes, such as WNT4 and RSPO1, may underlie the development of testicular tissue. Recent experimental and clinical evidence giving insight into SRY-negative 46,XX testicular or ovotesticular DSD is discussed. PMID:27055195

  3. Incorporating environmental concerns into power sector decision-making: A case study of Sri Lanka. World Bank Environment Paper 6

    SciTech Connect

    Meier, P.; Munasinghe, M.; Team, S.L.S.

    1994-04-01

    Weighs Sri Lanka`s options for addressing environmental concerns during the planning stages of energy policymaking. Here is a holistic approach to analyzing the environmental impact of various power systems. Unlike standard impact studies that begin at the project level, this method calls for environmental assessments that start at the planning stage of a national framework for energy policymaking. The framework would take into account the energy needs of Sri Lanka`s total economy. It also would make it easier to incorporate environmental goals into power sector decisionmaking at the critical investment stage. Sri Lanka`s development options for the power sector are reviewed in detail. Topics include alternative ways to assess the economic value of a power plant`s impact on biodiversity, human health, and air and water pollution. The study also assesses which energy planning options work best and recommends ways in which the Ceylon Electricity Board can improve its environmental policies.

  4. Testis development in the absence of SRY: chromosomal rearrangements at SOX9 and SOX3

    PubMed Central

    Vetro, Annalisa; Dehghani, Mohammad Reza; Kraoua, Lilia; Giorda, Roberto; Beri, Silvana; Cardarelli, Laura; Merico, Maurizio; Manolakos, Emmanouil; Parada-Bustamante, Alexis; Castro, Andrea; Radi, Orietta; Camerino, Giovanna; Brusco, Alfredo; Sabaghian, Marjan; Sofocleous, Crystalena; Forzano, Francesca; Palumbo, Pietro; Palumbo, Orazio; Calvano, Savino; Zelante, Leopoldo; Grammatico, Paola; Giglio, Sabrina; Basly, Mohamed; Chaabouni, Myriam; Carella, Massimo; Russo, Gianni; Bonaglia, Maria Clara; Zuffardi, Orsetta

    2015-01-01

    Duplications in the ~2 Mb desert region upstream of SOX9 at 17q24.3 may result in familial 46,XX disorders of sex development (DSD) without any effects on the XY background. A balanced translocation with its breakpoint falling within the same region has also been described in one XX DSD subject. We analyzed, by conventional and molecular cytogenetics, 19 novel SRY-negative unrelated 46,XX subjects both familial and sporadic, with isolated DSD. One of them had a de novo reciprocal t(11;17) translocation. Two cases carried partially overlapping 17q24.3 duplications ~500 kb upstream of SOX9, both inherited from their normal fathers. Breakpoints cloning showed that both duplications were in tandem, whereas the 17q in the reciprocal translocation was broken at ~800 kb upstream of SOX9, which is not only close to a previously described 46,XX DSD translocation, but also to translocations without any effects on the gonadal development. A further XX male, ascertained because of intellectual disability, carried a de novo cryptic duplication at Xq27.1, involving SOX3. CNVs involving SOX3 or its flanking regions have been reported in four XX DSD subjects. Collectively in our cohort of 19 novel cases of SRY-negative 46,XX DSD, the duplications upstream of SOX9 account for ~10.5% of the cases, and are responsible for the disease phenotype, even when inherited from a normal father. Translocations interrupting this region may also affect the gonadal development, possibly depending on the chromatin context of the recipient chromosome. SOX3 duplications may substitute SRY in some XX subjects. PMID:25351776

  5. Defect Engineering in SrI2:Eu2+ Single Crystal Scintillators

    DOE PAGESBeta

    Wu, Yuntao; Boatner, Lynn A.; Lindsey, Adam C.; Zhuravleva, Mariya; Jones, Steven; Auxier, John D.; Hall, Howard L.; Melcher, Charles L.

    2015-06-23

    Eu2+-activated strontium iodide is an excellent single crystal scintillator used for gamma-ray detection and significant effort is currently focused on the development of large-scale crystal growth techniques. A new approach of molten-salt pumping or so-called melt aging was recently applied to optimize the crystal quality and scintillation performance. Nevertheless, a detailed understanding of the underlying mechanism of this technique is still lacking. The main purpose of this paper is to conduct an in-depth study of the interplay between microstructure, trap centers and scintillation efficiency after melt aging treatment. Three SrI2:2 mol% Eu2+ single crystals with 16 mm diameter were grownmore » using the Bridgman method under identical growth conditions with the exception of the melt aging time (e.g. 0, 24 and 72 hours). Using energy-dispersive X-ray spectroscopy, it is found that the matrix composition of the finished crystal after melt aging treatment approaches the stoichiometric composition. The mechanism responsible for the formation of secondary phase inclusions in melt-aged SrI2:Eu2+ is discussed. Simultaneous improvement in light yield, energy resolution, scintillation decay-time and afterglow is achieved in melt-aged SrI2:Eu2+. The correlation between performance improvement and defect structure is addressed. The results of this paper lead to a better understanding of the effects of defect engineering in control and optimization of metal halide scintillators using the melt aging technique.« less

  6. The Malaysian Orthopaedic Association humanitarian mission to Indonesia and Sri Lanka.

    PubMed

    Sharaf, I; Saw, A; Hyzan, Y; Sivananthan, K S

    2005-07-01

    The tsunami which occurred off the west coast of North Sumatra on December 26, 2004 devastated the coastal areas of North Sumatra, South-West Thailand, South-East India and Sri Lanka killing more than a quarter of a million people. The destruction was enormous with many coastal villages destroyed. The other countries affected were Malaysia, Myanmar, Maldives, Bangladesh, Somalia, Kenya, Tanzania and the Seychelles. In January 2005, volunteers went in weekly rotation to Banda Aceh in collaboration with Global Peace Mission. These were Dr Hyzan Yusof, Dr Suryasmi Duski, Dr Sharaf Ibrahim, Dr Saw Aik, Dr Kamariah Nor and Dr Nor Azlin. In Banda Aceh, the surgical procedures that we could do were limited to external fixation of open fractures and debriding infected wounds at the Indonesian Red Crescent field hospital. In February, a team comprising Dato Dr K S Sivananthan, Dr T Kumar and Dr S Vasan spent a week in Sri Lanka. In Sri Lanka, Dato Sivananthan and his team were able to perform elective orthopaedic operations in Dr Poonambalam Memorial Hospital. We appealed for national and international aid and received support from local hospitals and the orthopaedic industry. International aid bound for Banda Aceh arrived in Kuala Lumpur from the Philippine Orthopaedic Association, the Chiba Children's Hospital in Japan and the Chinese Orthopaedic Association. The COA donated 1.5 tons of orthopaedic equipments. A special handing over ceremony from the COA to the Indonesian Orthopaedic Association was held in Putrajaya in March. Malaysia Airlines flew in the donated equipment to Kuala Lumpur while the onward flight to Aceh was provided by the Royal Malaysian Air Force. In April, Dr Saw Aik and Dr Yong Su Mei joined the Tsu-Chi International Medical Association for volunteer services on Batam Island, Indonesia. The MOA acknowledges the many individuals and organizations, both governmental and non-governmental, for their contributions in the humanitarian efforts. PMID

  7. Testis development in the absence of SRY: chromosomal rearrangements at SOX9 and SOX3.

    PubMed

    Vetro, Annalisa; Dehghani, Mohammad Reza; Kraoua, Lilia; Giorda, Roberto; Beri, Silvana; Cardarelli, Laura; Merico, Maurizio; Manolakos, Emmanouil; Parada-Bustamante, Alexis; Castro, Andrea; Radi, Orietta; Camerino, Giovanna; Brusco, Alfredo; Sabaghian, Marjan; Sofocleous, Crystalena; Forzano, Francesca; Palumbo, Pietro; Palumbo, Orazio; Calvano, Savino; Zelante, Leopoldo; Grammatico, Paola; Giglio, Sabrina; Basly, Mohamed; Chaabouni, Myriam; Carella, Massimo; Russo, Gianni; Bonaglia, Maria Clara; Zuffardi, Orsetta

    2015-08-01

    Duplications in the ~2 Mb desert region upstream of SOX9 at 17q24.3 may result in familial 46,XX disorders of sex development (DSD) without any effects on the XY background. A balanced translocation with its breakpoint falling within the same region has also been described in one XX DSD subject. We analyzed, by conventional and molecular cytogenetics, 19 novel SRY-negative unrelated 46,XX subjects both familial and sporadic, with isolated DSD. One of them had a de novo reciprocal t(11;17) translocation. Two cases carried partially overlapping 17q24.3 duplications ~500 kb upstream of SOX9, both inherited from their normal fathers. Breakpoints cloning showed that both duplications were in tandem, whereas the 17q in the reciprocal translocation was broken at ~800 kb upstream of SOX9, which is not only close to a previously described 46,XX DSD translocation, but also to translocations without any effects on the gonadal development. A further XX male, ascertained because of intellectual disability, carried a de novo cryptic duplication at Xq27.1, involving SOX3. CNVs involving SOX3 or its flanking regions have been reported in four XX DSD subjects. Collectively in our cohort of 19 novel cases of SRY-negative 46,XX DSD, the duplications upstream of SOX9 account for ~10.5% of the cases, and are responsible for the disease phenotype, even when inherited from a normal father. Translocations interrupting this region may also affect the gonadal development, possibly depending on the chromatin context of the recipient chromosome. SOX3 duplications may substitute SRY in some XX subjects. PMID:25351776

  8. Religious beliefs, possession States, and spirits: three case studies from sri lanka.

    PubMed

    Hanwella, Raveen; de Silva, Varuni; Yoosuf, Alam; Karunaratne, Sanjeewani; de Silva, Pushpa

    2012-01-01

    We describe three patients from different religious backgrounds in Sri Lanka whose possession states were strongly influenced by their religious beliefs. Patient A was a Buddhist who claimed to have special powers given by a local deity named Paththini. Patient B was a Catholic who experienced spirits around her whom she believed were sent by Satan. Patient C was a Muslim and believed she was possessed by spirits. The religious beliefs also influenced the help-seeking behaviour and the rituals or treatments to which they responded. PMID:22970398

  9. Religious Beliefs, Possession States, and Spirits: Three Case Studies from Sri Lanka

    PubMed Central

    Hanwella, Raveen; de Silva, Varuni; Yoosuf, Alam; Karunaratne, Sanjeewani; de Silva, Pushpa

    2012-01-01

    We describe three patients from different religious backgrounds in Sri Lanka whose possession states were strongly influenced by their religious beliefs. Patient A was a Buddhist who claimed to have special powers given by a local deity named Paththini. Patient B was a Catholic who experienced spirits around her whom she believed were sent by Satan. Patient C was a Muslim and believed she was possessed by spirits. The religious beliefs also influenced the help-seeking behaviour and the rituals or treatments to which they responded. PMID:22970398

  10. Laboratory studies of Miocene limestone for the use of construction industry in Sri Lanka

    NASA Astrophysics Data System (ADS)

    de Silva Jayawardena, Upali

    2016-04-01

    Geologically ten percent of Sri Lanka is made up of Miocene limestone which covers northern and north-western coastal belt of the Island. It is used as a raw material for various industries but only cement and lime are being used for the construction industry. Except its chemical composition there is no available literature to study about other properties. Therefore the author carried out a series of laboratory tests to find out the mechanical properties of limestone in Sri Lanka. The objective of this paper is to make a note on the various properties of Miocene limestone and describe its suitability to use as an aggregate for the construction industry in Sri Lanka. Borehole samples (NX size) of limestone were obtained from various drilling sites in Northern Province of Sri Lanka and selected samples were prepared for different laboratory tests after visual observations. The tests were carried out according to ASTM Standards at the geotechnical and materials testing laboratories. The number of samples per each test was different. The range (and average result) for each property can be mentioned here as bulk density 2213-2643 (2452) kg/m3, water absorption 2.2-4.5 (1.91)%, porosity 1-15 (6.5)%, specific gravity 2.58-2.68(2.62), ultrasonic pulse velocity P wave 4480-6338 (5668) m/s and S wave 2688-3802 (3400) m/s, uniaxial compressive strength 11-92 (35)MPa, point load strength 1.2-7.1 (3.7)MPa, aggregate impact value, AIV 25-30 (28)%, LAAV 35-38 (36)%, and Brazilian tensile strength 2.1-4.4 (3.2)MPa. Poisson's ratio 0.12-0.68 (0.22) and modulus of elasticity 42-85 (62) GPa were obtained by using P and S ultrasonic wave velocity values. According to LAAV and AIV this limestone may be suitable as the base course material for road construction but may not be suitable for surface material of highways and rail road ballasts. Ultrasonic velocity waves indicate that limestone is highly compacted and solid. According to the compressive strength of solid limestone rock a few

  11. Ayurvedic heritage of J & K: a review of Sri Ranbira Cikitsa Sudha Sāra.

    PubMed

    Kumar, A; Singh, G; Kumar, N

    2001-01-01

    This work reviews the contents of an Ayurvedic treatise "Sri Ranbira Cikitsa Sudha Sāra" authored by Kaviraj Neel Kanth in the year 1931 of Vikrami, in 'Takari' script, the official script during the reign of his highness Maharaja Ranbir Singh of Jammu and Kashmir. A copy of the book is presently available with Raghunath Sanskrit Library, Jammu in torn condition. This is a humble effort by the authors for the exploration of hidden and old Ayurvedic literature of Jammu and Kashmir. PMID:12841189

  12. Health changes in Sri Lanka: benefits of primary health care and public health.

    PubMed

    Karunathilake, Indika Mahesh

    2012-07-01

    The Democratic Socialist Republic of Sri Lanka is an island in the Indian Ocean that has achieved a unique status in the world with health indicators that are comparable with those of developed countries. This is illustrated, among others, by the reduction in both child and maternal mortality in the country. This achievement is the result of a range of long-term interventions, including providing education and health care free of charge, training of health care workers, developing public health infrastructure in rural areas, and adopting steps to improve sanitation, nutrition, and immunization coverage. PMID:22815304

  13. Seroprevalence of Toxoplasma gondii antibodies in captive elephants (Elephaus maximus maximus) in Sri Lanka.

    PubMed

    Dangolla, A; Ekanayake, D K; Rajapakse, R P V J; Dubey, J P; Silva, I D

    2006-04-15

    Serum samples collected during August 2003-June 2004 from 45 privately owned captive and 8 elephants from the Pinnawala Elephant Orphanage were tested for the presence of antibodies against Toxoplasma gondii using the direct modified agglutination test (MAT). Antibodies were found in sera of 14 of 45 (32%) privately owned elephants with titers of 1:25 in three, 1:50 in three, 1:100 in three, 1:200 in three, and 1:400 in three elephants. The elephants from Pinnawala Elephant Orphanage were seronegative. This is the first report of T. gondii seroprevalence in elephants in Sri Lanka. PMID:16414192

  14. The SRI24 Multi-Channel Brain Atlas

    PubMed Central

    Rohlfing, Torsten; Zahr, Natalie M.; Sullivan, Edith V.; Pfefferbaum, Adolf

    2009-01-01

    We present a new standard atlas of the human brain based on magnetic resonance images. The atlas was generated using unbiased population registration from high-resolution images obtained by multichannel-coil acquisition at 3T in a group of 24 normal subjects. The final atlas comprises three anatomical channels (T1-weighted, early and late spin echo), three diffusion-related channels (fractional anisotropy, mean diffusivity, diffusion-weighted image), and three tissue probability maps (CSF, gray matter, white matter). The atlas is dynamic in that it is implicitly represented by nonrigid transformations between the 24 subject images, as well as distortion-correction alignments between the image channels in each subject. The atlas can, therefore, be generated at essentially arbitrary image resolutions and orientations (e.g., AC/PC aligned), without compounding interpolation artifacts. We demonstrate in this paper two different applications of the atlas: (a) region definition by label propagation in a fiber tracking study is enabled by the increased sharpness of our atlas compared with other available atlases, and (b) spatial normalization is enabled by its average shape property. In summary, our atlas has unique features and will be made available to the scientific community as a resource and reference system for future imaging-based studies of the human brain. PMID:19183706

  15. The SRI24 multichannel brain atlas: construction and applications

    NASA Astrophysics Data System (ADS)

    Rohlfing, Torsten; Zahr, Natalie M.; Sullivan, Edith V.; Pfefferbaum, Adolf

    2008-03-01

    We present a new standard atlas of the human brain based on magnetic resonance images. The atlas was generated using unbiased population registration from high-resolution images obtained by multichannel-coil acquisition at 3T in a group of 24 normal subjects. The final atlas comprises three anatomical channels (T I-weighted, early and late spin echo), three diffusion-related channels (fractional anisotropy, mean diffusivity, diffusion-weighted image), and three tissue probability maps (CSF, gray matter, white matter). The atlas is dynamic in that it is implicitly represented by nonrigid transformations between the 24 subject images, as well as distortion-correction alignments between the image channels in each subject. The atlas can, therefore, be generated at essentially arbitrary image resolutions and orientations (e.g., AC/PC aligned), without compounding interpolation artifacts. We demonstrate in this paper two different applications of the atlas: (a) region definition by label propagation in a fiber tracking study is enabled by the increased sharpness of our atlas compared with other available atlases, and (b) spatial normalization is enabled by its average shape property. In summary, our atlas has unique features and will be made available to the scientific community as a resource and reference system for future imaging-based studies of the human brain.

  16. Assessing the changes of groundwater recharge / irrigation water use between SRI and traditional irrigation schemes in Central Taiwan

    NASA Astrophysics Data System (ADS)

    Chen, Shih-Kai; Jang, Cheng-Shin; Tsai, Cheng-Bin

    2015-04-01

    To respond to agricultural water shortage impacted by climate change without affecting rice yield in the future, the application of water-saving irrigation, such as SRI methodology, is considered to be adopted in rice-cultivation in Taiwan. However, the flooded paddy fields could be considered as an important source of groundwater recharge in Central Taiwan. The water-saving benefit of this new methodology and its impact on the reducing of groundwater recharge should be integrally assessed in this area. The objective of this study was to evaluate the changes of groundwater recharge/ irrigation water use between the SRI and traditional irrigation schemes (continuous irrigation, rotational irrigation). An experimental paddy field located in the proximal area of the Choushui River alluvial fan (the largest groundwater pumping region in Taiwan) was chosen as the study area. The 3-D finite element groundwater model (FEMWATER) with the variable boundary condition analog functions, was applied in simulating groundwater recharge process and amount under traditional irrigation schemes and SRI methodology. The use of effective rainfall was taken into account or not in different simulation scenarios for each irrigation scheme. The simulation results showed that there were no significant variations of infiltration rate in the use of effective rainfall or not, but the low soil moisture setting in deep soil layers resulted in higher infiltration rate. Taking the use of effective rainfall into account, the average infiltration rate for continuous irrigation, rotational irrigation, and SRI methodology in the first crop season of 2013 were 4.04 mm/day, 4.00 mm/day and 3.92 mm/day, respectively. The groundwater recharge amount of SRI methodology was slightly lower than those of traditional irrigation schemes, reducing 4% and 2% compared with continuous irrigation and rotational irrigation, respectively. The field irrigation requirement amount of SRI methodology was significantly

  17. Cardiac involvement in dengue virus infections during the 2004/2005 dengue fever season in Sri Lanka.

    PubMed

    Wichmann, Dominic; Kularatne, Senanayake; Ehrhardt, Stephan; Wijesinghe, Sriyal; Brattig, Norbert W; Abel, Walter; Burchard, Gerd D

    2009-07-01

    Sri Lanka experienced a dramatic increase in dengue cases (15,400) in the 2004 - 2005 season. We carried out a prospective study to investigate cardiac involvement in dengue virus infected patients during the 2004 - 2005 season in Peradeniya, Central Province, Sri Lanka. Cardiac involvement was defined as elevated levels of myoglobin, creatine kinase-muscle brain-type, N-terminal pro-brain natriuretic peptide, heart-type fatty acid-binding protein and troponin T. Twenty-five percent of dengue virus infected patients had one or more of the above tests with abnormal results. PMID:19842405

  18. South Asian co-operation in population education. Materials jointly developed for common use by South Asian population education programmes.

    PubMed

    1992-01-01

    Southern Asian population education programs have developed common materials on population and family life education. Countries involved were Bangladesh, India, Nepal, Pakistan, and Sri Lanka. The development of materials occurred as a byproduct of workshop conducted in Nepal from December 3-7, 1990 and December 2-10, 1991 in Sri Lanka. The 1st meeting was organized by UNESCO's Population Education Advisory team, and 6 curriculum topics were identified. Pretesting of materials was conducted between meetings. The final product was a set of 10 posters and 2 comic strips on the quality of life developed by India for elementary level use; a family life and sex education syllabus developed by Sri Lanka for secondary school use; 5 modules with teacher's guides and sample lessons for secondary school use; 5 modules and a teacher's guide on transmission of values on population education by Pakistan; 25 flip charts on maternal and child health for illiterates developed by Nepal; and a field guide on environmental protection for nonformal field workers developed by Bangladesh. Materials were designed through brainstorming sessions, designing of materials by experts, review by other groups, and retesting on target audiences. Revision followed pretesting. The plan for assuring use of materials was to have UNESCO print prototypes and then participants would seek financial support for country supplies. A suggestion was made to leave ample space for insertion of local language captions. Another suggestion was that the cartoon strip "Girls are Pearls" be printed on students' exercise books for all member countries. Member countries should also have available selected materials translated into English and distributed. UNESCO should continue to play the role of facilitator of information and expertise exchange among member countries. Another mutually cooperative activity was the Group Training Course on Population Education for the South Asian subregion held in December 1991. PMID

  19. Mapping mental health finances in Ghana, Uganda, Sri Lanka, India and Lao PDR

    PubMed Central

    2010-01-01

    Background Limited evidence about mental health finances in low and middle-income countries is a key challenge to mental health care policy initiatives. This study aimed to map mental health finances in Ghana, Uganda, India (Kerala state), Sri Lanka and Lao PDR focusing on how much money is available for mental health, how it is spent, and how this impacts mental health services. Methods A researcher in each region reviewed public mental health-related budgets and interviewed key informants on government mental health financing. A total of 43 key informant interviews were conducted. Quantitative data was analyzed in an excel matrix using descriptive statistics. Key informant interviews were coded a priori against research questions. Results National ring-fenced budgets for mental health as a percentage of national health spending for 2007-08 is 1.7% in Sri Lanka, 3.7% in Ghana, 2.0% in Kerala (India) and 6.6% in Uganda. Budgets were not available in Lao PDR. The majority of ring-fenced budgets (76% to 100%) is spent on psychiatric hospitals. Mental health spending could not be tracked beyond the psychiatric hospital level due to limited information at the health centre and community levels. Conclusions Mental health budget information should be tracked and made publically accessible. Governments can adapt WHO AIMS indicators for reviewing national mental health finances. Funding allocations work more effectively through decentralization. Mental health financing should reflect new ideas emerging from community based practice in LMICs. PMID:20507558

  20. Physics of the environment: possible Sumatra Tsunami warning times for large animals in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Browning, David G.; Scheifele, Peter M.; Vonwinkle, William A.

    2005-04-01

    There has previously been significant anecdotal evidence that animals can anticipate or sense seismic events. It is known that large animals, specifically elephants, sense and utilize low frequency sound. The object of this paper is to estimate the possible warning times that large animals in Sri Lanka could have had of the Sumatra Tsunami, assuming they could sense low frequency wave transmission from the initial earthquake arriving by either atmospheric, ocean, or bottom paths. The atmospheric path appears to be the least efficient due to relatively high attenuation and poor coupling to the source. It would also give the shortest warning time: approximately 30 minutes. The ocean path via the deep sound channel, which has been shown by a previous Bermuda experiment to be an efficient means of coupling seismic energy to an island, would give a warning time of more than 1.5 hours. The bottom path(s), which gave strong received signals at a Sri Lanka seismic station, would give a warning time of about 2 hours. These estimates should provide a context for animal behavior reports.

  1. Ompok argestes, a new species of silurid catfish endemic to Sri Lanka (Teleostei: Siluridae).

    PubMed

    Sudasinghe, Hiranya; Meegaskumbura, Madhava

    2016-01-01

    Ompok argestes, a new species of silurid catfish, is described from the southwestern lowlands of Sri Lanka. The new species is distinguished from all other species of Ompok in the Indian subcontinent by a combination of the following characters: body color pattern mottled; predorsal profile uniformly convex; maxillary barbels reach or extend slightly beyond base of dorsal fin; eye diameter 14.2-17.1% head length (HL); body depth at anus 19.8-22.3% standard length (SL); head width 14.3-16.8% SL; caudal peduncle depth 5.6-6.5% SL. Callichrous ceylonensis Günther is shown to be a valid species that is apparently restricted to Sri Lanka, distinguished by a combination of the following characters: distinct concavity in predorsal profile; origin of pelvic fin beneath or slightly posterior to the origin of the dorsal fin; maxillary barbels 108-166 % HL; mandibular barbels 16.1-33.7 % HL; and 58-66 anal-fin rays. PMID:27615884

  2. Evolution of dengue in Sri Lanka-changes in the virus, vector, and climate.

    PubMed

    Sirisena, P D N N; Noordeen, F

    2014-02-01

    Despite the presence of dengue in Sri Lanka since the early 1960s, dengue has become a major public health issue, with a high morbidity and mortality. Aedes aegypti and Aedes albopictus are the vectors responsible for the transmission of dengue viruses (DENV). The four DENV serotypes (1, 2, 3, and 4) have been co-circulating in Sri Lanka for more than 30 years. The new genotype of DENV-1 has replaced an old genotype, and new clades of DENV-3 genotype III have replaced older clades. The emergence of new clades of DENV-3 in the recent past coincided with an abrupt increase in the number of dengue fever (DF)/dengue hemorrhagic fever (DHF) cases, implicating this serotype in severe epidemics. Climatic factors play a pivotal role in the epidemiological pattern of DF/DHF in terms of the number of cases, severity of illness, shifts in affected age groups, and the expansion of spread from urban to rural areas. There is a regular incidence of DF/DHF throughout the year, with the highest incidence during the rainy months. To reduce the morbidity and mortality associated with DF/DHF, it is important to implement effective vector control programs in the country. The economic impact of DF/DHF results from the expenditure on DF/DHF critical care units in several hospitals and the cost of case management. PMID:24334026

  3. First-principles study of hole polaron formation and migration in SrI2

    NASA Astrophysics Data System (ADS)

    Zhou, Fei; Sadigh, Babak; Aberg, Daniel

    2015-03-01

    We investigate the formation of self-trapped holes (STH) in the high performance scintillator material SrI2 using a recently developed first principles method, polaron self-interaction correction (pSIC). pSIC removes the significant spurious self-interaction of localized polaron states. It is capable of accurately reproduce the configurational energy landscape of polaronic states from optimized hybrid functionals at the computational cost of the local density approximation. We searched for and identified all symmetrically distinct STH states localized on neighboring I-I dimers, i.e. Vk centers, and found non-trivial relation between the STH formation energies and dimer separation. All possible polaron hopping paths of the type IAIB -->IBIC are investigated systematically with pSIC and the elastic band method, and paths with low migration barrier energy of about 0.2 eV were identified, suggesting high mobility in SrI2. We expect that the present approach can be applied to study polaron formation and migration in other materials. Support from the National Nuclear Security Administration Office of Nonproliferation Research and Development (NA-22) is acknowledged. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore N We acknowledge funding from the NA-22 agency.

  4. Progress on the SRI/ENEA Collaboration to Investigate Gaseous D2 / Pd Nuclear Effects

    NASA Astrophysics Data System (ADS)

    McKubre, Michael C. H.; Tanzella, Francis L.; Tripodi, Paolo; Violante, Vittorio

    2002-03-01

    A collaborative effort has been established formally between SRI and ENEA researchers to test and demonstrate the cross-laboratory replicability of gas phase Pd/D2 excess heat, helium and tritium observations. Similar facilities are being established in both countries to allow on-line determination of heat effects correlated with helium-4, and ultimately helium-3 measurements from so called "Case" experiments involving the application of modest temperatures and D2 gas pressures to a packed bed of palladium on carbon catalyst and other finely divided palladium materials. The results of experiments performed under similar protocols will be examined and compared. A second facet of this collaboration is the joint attempt to replicate the production of tritium in an "Arata-Zhang" hollow, double-structured cathode. Two massive hollow palladium electrodes were manufactured at ENEA and sealed to contain palladium black within the enclosed void. These electrodes presently are being operated at SRI as electrolytic cathodes in LiOD electrolyte. On experiment termination these will be sectioned and the contents examined for helium-4, helium-3 and evidence of tritium.

  5. Ayurveda: a multilectic interpretation.

    PubMed

    Nordstrom, C R

    1989-01-01

    Ayurveda, in practice, comprises far more than a medical tradition in Sri Lanka. It provides, in addition to a manuscript for health care, a popular knowledge paradigm by which the population addresses social, epistemological and ontological issues in their lives. The concept of health expands to include the many existential levels that are basic to a definition of the self and the many arenas of life in which it is made evident. The concept of 'multilectic' process is introduced in this paper to explain this dynamic that characterizes popular Ayurveda, a dynamic that Sri Lankans specify as consisting of a fundamental complex interplay of mutually interrelated factors that are capable of referencing multiple meanings and life contingencies neither contradictory, dichotomous, nor unidirectional in nature. Because of the extent to which Ayurveda is embedded in the everyday lives and fundamental conceptual frameworks of the Sri Lankans, it is likely to remain an integrating knowledge system and a powerful explanatory paradigm in their general lives as well as for their health care dilemmas. PMID:2652328

  6. Escalating chronic kidney diseases of multi-factorial origin in Sri Lanka: causes, solutions, and recommendations.

    PubMed

    Wimalawansa, Sunil J

    2014-11-01

    During the last two decades, Sri Lanka, located close to the equator, has experienced an escalating incidence of chronic kidney disease (CKD) of unknown aetiology (CKDue) in dry zonal areas. Similar incidences of unusual CKDs have been reported in the dry zonal, agricultural areas of several other equatorial countries. In Sri Lanka, the incidence of CKDue is highest in the North Central Province (NCP), where approximately 45 % of the country's paddy fields are located. However, in recent years, the disease has spread into areas adjacent to as well as distant from the NCP. The cause of CKD in Sri Lanka is unknown, and may likely due to interactions of different potential agents; thus, CKD is of multi-factorial origin (CKD-mfo). These factors include, the negative effects from overuse of agrochemicals. Nevertheless, the potential interactions and synergism between probable agents have not been studied. This systematic review discusses the proposed hypotheses and causes of CKD-mfo in Sri Lanka, and ways to decrease the incidence of this disease and to eradicate it, and provide some recommendations. During the past decade, a number of groups have investigated this disorder using different methodologies and reported various correlations, but failed to find a cause. Research has focussed on the contamination of water with heavy metals, agrochemicals, hard water, algae, ionicity, climate change, and so forth. Nevertheless, the levels of any of the pollutants or conditions reported in water in NPC are inconsistent not correlated with the prevalence of the disease, and are too low to be the sole cause of CKD-mfo. Meanwhile, several nephrotoxins prevalent in the region, including medications, leptospirosis, toxic herbs, illicit alcohol, locally grown tobacco, and petrochemicals, as well as the effects of changed habits occured over the past four decades have not been studied to date. Taken together, the geographical distribution and overall findings indicate that

  7. The Importance of Poisoning vs. Road Traffic Injuries as a Cause of Death in Rural Sri Lanka

    PubMed Central

    Eddleston, Michael; Udayakumara, Nilantha; Adhikari, Sriyantha; de Silva, Dhamika; Sheriff, M. H. Rezvi; Waidyaratne, Dhananjaya L.

    2007-01-01

    Background Road traffic crashes are considered by the WHO to be the most important global cause of death from injury. However, this may not be true for large areas of rural Asia where road vehicles are uncommon. The issue is important, since emphasising the importance of road traffic crashes risks switching resources to urban areas, away from already underfunded rural regions. In this study, we compared the importance of road traffic crashes with other forms of injury in a poor rural region of South Asia. Methodology/Principal Findings We collected data on all deaths from injury in the North Central Province of Sri Lanka (NCP; population 1,105,198 at 2001 census) over 18 months using coronial, hospital, and police data. We calculated the incidence of death from all forms of intentional and unintentional injury in the province. The annual incidence of death from injury in the province was high: 84.2 per 100,000 population. Half of the deaths were from self-harm (41.3/100,000). Poisoning (35.7/100,000)—in particular, pesticide self-poisoning (23.7/100,000)—was the most common cause of death, being 3.9-fold more common than road traffic crashes (9.1/100,000). Conclusions/Significance In poor rural regions of South Asia, fatal self-harm and pesticide self-poisoning in particular are significantly more important than road traffic injuries as a cause of death. It is possible that the data used by the WHO to calculate global injury estimates are biased towards urban areas with better data collection but little pesticide poisoning. More studies are required to inform a debate about the importance of different forms of injury and how avoidable deaths from any cause can be prevented. In the meantime, marked improvements in the effectiveness of therapy for pesticide poisoning, safer storage, reduced pesticide use, or reductions in pesticide toxicity are required urgently to reduce the number of deaths from self-poisoning in rural Asia. PMID:17622344

  8. Farmer Resettlements and Water Energy Stresses Arising From Aggravating Drought Conditions in Mahaweli River Watershed, Sri Lanka

    NASA Astrophysics Data System (ADS)

    Thabrew, L.

    2012-12-01

    Climate change is expected to cause significant changes in water quantity and water quality in river basins throughout the world, with particularly significant impacts in developing regions. Climate change effects are often exacerbated by other simultaneous activities in developing countries, such as population growth, reliance on subsistence agriculture, and expanding provision of electricity. Each of these activities requires access to readily-available freshwater. For example, population growth requires more water for irrigation as food production needs increase. Additionally, water is needed for generating electricity in hydropower facilities as well as other facilities, which require water to run steam turbines or to cool facilities. As such, many developing countries face the real and immediate need to anticipate and adapt to climatic stresses on water resources in both the agricultural and residential sectors. Water withdrawal in both of these sectors is largely driven by individual behaviors, such as electricity use in the home and irrigation practices on farmland, aggregated at the household, community, and regional level. Our ongoing project in Sri Lanka focuses on understanding aforementioned issues in coupled natural and human systems in the Mahaweli River Watershed (MWR) to inform decision-makers to streamline policies and strategies for effective adaptation to worsening drought conditions. MWR produces more than 60% of the rice demand and nearly 40% of the energy requirement of the country. Although irrigation is currently the sector that withdraws the most water, with government plans for resettling farmer communities and developing new urban centers in the region by 2030, electricity production is expected to compete for water against irrigation in the future. Thus, understanding the water-energy nexus is crucial to planning for conservation and efficiency. Through a pilot survey conducted by our interdisciplinary research team, in five locations in

  9. Large-scale deforestation for plantation agriculture in the hill country of Sri Lanka and its impacts

    NASA Astrophysics Data System (ADS)

    Wickramagamage, P.

    1998-10-01

    The forest cover in the hill country river catchment areas of Sri Lanka has been reduced to isolated patches on hilltops and a handful of reserves above the 1524 m (5000 ft) contour. Most of the land that was under forest cover at the turn of the nineteenth century is now covered with plantation crops. The districts of Kandy, Matale, Nuwara Eliya, Badulla, Ratnapura and Kegalle are the main hill country plantation areas. Within a period of less than half a century most of the forests in the hill country were cleared for plantation crops. Shifting cultivation was responsible for deforestation in the drier parts of the hill country. At the time of the British conquest of the hill country, the population of the whole island was not more than 3/4 to 1 million and they had settled in isolated villages at elevations below 1066 m. Subsistence agriculture was the main occupation of this predominantly rural population.During the first phase (1830-1880) of the plantation industry, large tracts of mostly forest land were cleared for coffee cultivation. By 1878, the extent of the coffee plantations reached its maximum of 111 336 ha most of which was situated in the wet zone hill country. The second phase of plantation agriculture began as the coffee industry was completely wiped out by a leaf disease. Most of the abandoned coffee plantations and the remaining forests were converted to tea, rubber and cinchona estates. The first two crops managed to survive price fluctuations in the world market, while the latter collapsed because of over production.During the period of large-scale deforestation in the hill country, the climate also underwent changes as exemplified by rainfall and temperature trends. However, these trends are not uniform everywhere in the plantation areas of the hill country. The temperature has risen a few degrees over a period of about a century and quarter in the hill country stations, while rainfall has declined significantly at some stations. These changes

  10. Formula Funding and Decentralized Management of Schools--Has It Improved Resource Allocation in Schools in Sri Lanka?

    ERIC Educational Resources Information Center

    Arunatilake, Nisha; Jayawardena, Priyanka

    2010-01-01

    Using the experience of the Educational Quality Inputs (EQI) Scheme in Sri Lanka the paper examines the distributional aspects of formula-based funding and efficiency of decentralized management of education funds in a developing country setting. The study finds that the EQI fund distribution is largely pro-poor. However, results show that to…

  11. A Comparative Study of Student Support Services of Allama Iqbal Open University and the Open University of Sri Lanka

    ERIC Educational Resources Information Center

    Gujjar, Aijaz Ahmed; Chaudhry, Bushra Naoreen; Chaudhry, Amtul Hafeez

    2009-01-01

    This paper attempts to compare the availability, quality, similarities and differences in student support services offered by the Allama Iqbal Open University (AIOU) Pakistan and The Open University of Sri Lanka (OUSL). It also aims to identify and report the deficiencies that students of both the institutions face in the student support services.…

  12. Facilitating Long-Term Recovery from Natural Disasters: Psychosocial Programming for Tsunami-Affected Schools of Sri Lanka

    ERIC Educational Resources Information Center

    Nastasi, Bonnie K.; Jayasena, Asoka; Summerville, Meredith; Borja, Amanda P.

    2011-01-01

    This article reports the findings of a school-based intervention project conducted in the Southern Province of Sri Lanka 15 to 18 months after the December 2004 Tsunami. The work responds to the need for culturally relevant programming to address long-term psychosocial recovery of children and adolescents affected by large scale disasters. Program…

  13. Wives' Attitudes toward Gender Roles and Their Experience of Intimate Partner Violence by Husbands in Central Province, Sri Lanka

    ERIC Educational Resources Information Center

    Jayatilleke, Achini; Poudel, Krishna C.; Sakisaka, Kayako; Yasuoka, Junko; Jayatilleke, Achala Upendra; Jimba, Masamine

    2011-01-01

    The authors conducted a community based, cross-sectional study to describe the prevalence of intimate partner violence (IPV) by husbands and the association between wives' attitudes toward gender roles and their experience of IPV in Central Province, Sri Lanka. This article included a representative sample of 624 wives between 15 and 49 years of…

  14. Molecular characterization of banana bunchy top virus isolate from Sri Lanka and its genetic relationship with other isolates.

    PubMed

    Wickramaarachchi, W A R T; Shankarappa, K S; Rangaswamy, K T; Maruthi, M N; Rajapakse, R G A S; Ghosh, Saptarshi

    2016-06-01

    Bunchy top disease of banana caused by Banana bunchy top virus (BBTV, genus Babuvirus family Nanoviridae) is one of the most important constraints in production of banana in the different parts of the world. Six genomic DNA components of BBTV isolate from Kandy, Sri Lanka (BBTV-K) were amplified by polymerase chain reaction (PCR) with specific primers using total DNA extracted from banana tissues showing typical symptoms of bunchy top disease. The amplicons were of expected size of 1.0-1.1 kb, which were cloned and sequenced. Analysis of sequence data revealed the presence of six DNA components; DNA-R, DNA-U3, DNA-S, DNA-N, DNA-M and DNA-C for Sri Lanka isolate. Comparisons of sequence data of DNA components followed by the phylogenetic analysis, grouped Sri Lanka-(Kandy) isolate in the Pacific Indian Oceans (PIO) group. Sri Lanka-(Kandy) isolate of BBTV is classified a new member of PIO group based on analysis of six components of the virus. PMID:27366766

  15. Comparative Study of Pre-Service Teacher Education Programme at Secondary Stage in Bangladesh, India, Pakistan and Sri Lanka

    ERIC Educational Resources Information Center

    Yadav, S. K.

    2011-01-01

    The present research work has studied and compared the different issues of pre-service teacher education programme in India, Sri Lanka, Bangladesh and Pakistan. The data were collected from 24 principals, 88 teacher educators and 157 student teachers from institutions and universities where Bachelor of Education (B.Ed.) course were. The data were…

  16. Sustainability and Local People's Participation in Coastal Aquaculture: Regional Differences and Historical Experiences in Sri Lanka and the Philippines

    NASA Astrophysics Data System (ADS)

    Bergquist, Daniel A.

    2007-11-01

    This article discusses environmental sustainability in aquaculture and its contribution to poverty alleviation, based on field studies in Sri Lanka and the Philippines. The aquaculture practices studied are the monoculture of the black tiger prawn ( Penneaus monodon) and milkfish ( Chanos chanos) and the polyculture of the two species together with the mud crab ( Scylla serrata). Factors affecting economic viability, social equity and environmental impacts in aquaculture are discussed and used to illuminate local and regional differences between aquaculture in Sri Lanka and the Philippines. Findings indicate that the most significant difference is the level of participation by local people (i.e., people originating ≤10 km away from the farm location). In the Philippines, 84 % of the people involved in aquaculture are locals, whereas in Sri Lanka, 55% are outsiders. Whether differences between the two areas can be explained by analyzing regional conditions, which might have resulted in different aquaculture practices, is discussed. In Sri Lanka, semi-intensive shrimp monoculture is currently the most common practice, whereas in the Philippines, extensive shrimp/fish polyculture is more common. Previous studies, as well as fieldwork, indicate that extensive culture practices reduce environmental impacts and benefit local people more. Sustainability in aquaculture is, however, also dependent on the extent of mangrove conversion into ponds. As such, extensive and locally owned farms do not necessarily result in an all but sustainable situation. Keeping this in mind, it is discussed if extensive polyculture practices might result in a more sustainable aquaculture, both environmentally and socioeconomically.

  17. Understanding School Health Environment through Interviews with Key Stakeholders in Lao PDR, Mongolia, Nepal and Sri Lanka

    ERIC Educational Resources Information Center

    Park, Sohyun; Lee, Eun Young; Gittelsohn, Joel; Nkala, Denis; Choi, Bo Youl

    2015-01-01

    Studies on health promoting schools (HPS) in low- and middle-income countries (LMICs) are scarce. To contribute to the development of HPS in these countries, we conducted formative research to understand the school environment in Lao PDR, Mongolia, Nepal, and Sri Lanka. Forty-three teachers, 10 government workers and 5 parents participated in…

  18. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, EXPLOSIVES DETECTION TECHNOLOGY, SRI INSTRUMENTS, MODEL 8610C, GAS CHROMATOGRAPH/THERMIONIC IONIZATION DETECTION

    EPA Science Inventory

    The SRI Model 86 1 OC gas chromatograph (GC) is a transportable instrument that can provide on-site analysis of soils for explosives. Coupling this transportable gas chromatograph with a thermionic ionization detector (TID) allows for the determination of explosives in soil matri...

  19. Sustainability and local people's participation in coastal aquaculture: regional differences and historical experiences in Sri Lanka and the Philippines.

    PubMed

    Bergquist, Daniel A

    2007-11-01

    This article discusses environmental sustainability in aquaculture and its contribution to poverty alleviation, based on field studies in Sri Lanka and the Philippines. The aquaculture practices studied are the monoculture of the black tiger prawn (Penneaus monodon) and milkfish (Chanos chanos) and the polyculture of the two species together with the mud crab (Scylla serrata). Factors affecting economic viability, social equity and environmental impacts in aquaculture are discussed and used to illuminate local and regional differences between aquaculture in Sri Lanka and the Philippines. Findings indicate that the most significant difference is the level of participation by local people (i.e., people originating < or =10 km away from the farm location). In the Philippines, 84 % of the people involved in aquaculture are locals, whereas in Sri Lanka, 55% are outsiders. Whether differences between the two areas can be explained by analyzing regional conditions, which might have resulted in different aquaculture practices, is discussed. In Sri Lanka, semi-intensive shrimp monoculture is currently the most common practice, whereas in the Philippines, extensive shrimp/fish polyculture is more common. Previous studies, as well as fieldwork, indicate that extensive culture practices reduce environmental impacts and benefit local people more. Sustainability in aquaculture is, however, also dependent on the extent of mangrove conversion into ponds. As such, extensive and locally owned farms do not necessarily result in an all but sustainable situation. Keeping this in mind, it is discussed if extensive polyculture practices might result in a more sustainable aquaculture, both environmentally and socioeconomically. PMID:17929084

  20. Similarities and differences of X and Y chromosome homologous genes, SRY and SOX3, in regulating the renin-angiotensin system promoters

    PubMed Central

    Araujo, Fabiano C.; Milsted, Amy; Watanabe, Ingrid K. M.; Del Puerto, Helen L.; Santos, Robson A. S.; Lazar, Jozef; Reis, Fernando M.

    2015-01-01

    The renin-angiotensin system (RAS) is subject to sex-specific modulation by hormones and gene products. However, sex differences in the balance between the vasoconstrictor/proliferative ACE/ANG II/AT1 axis, and the vasodilator/antiproliferative ACE2/ANG-(1–7)/MAS axis are poorly known. Data in the rat have suggested the male-specific Y-chromosome gene Sry to contribute to balance between these two axes, but why the testis-determining gene has these functions remains unknown. A combination of in silico genetic/protein comparisons, functional luciferase assays for promoters of the human RAS, and RNA-Seq profiling in rat were used to address if regulation of Sry on the RAS is conserved in the homologous X-chromosome gene, Sox3. Both SRY and SOX3 upregulated the promoter of Angiotensinogen (AGT) and downregulated the promoters of ACE2, AT2, and MAS, likely through overlapping mechanisms. The regulation by both SRY and SOX3 on the MAS promoter indicates a cis regulation through multiple SOX binding sites. The Renin (REN) promoter is upregulated by SRY and downregulated by SOX3, likely through trans and cis mechanisms, respectively. Sry transcripts are found in all analyzed male rat tissues including the kidney, while Sox3 transcripts are found only in the brain and testis, suggesting that the primary tissue for renin production (kidney) can only be regulated by SRY and not SOX3. These results suggest that SRY regulation of the RAS is partially shared with its X-chromosome homolog SOX3, but SRY gained a sex-specific control in the kidney for the rate-limiting step of the RAS, potentially resulting in male-specific blood pressure regulation. PMID:25759379

  1. Gender-specific socioeconomic impacts of development programs in Sri Lanka.

    PubMed

    Stoeckel, J; Sirisena, N L

    1988-10-01

    Data from a Sri Lanka national sample survey -- 3597 households stratified on the basis of development program areas -- were analyzed to compare impacts of 3 national development programs and their combinations upon the occupational and income status of females and males in Sri Lanka. These programs, implemented over the last 30 years, are guaranteed price schemes that develop markets for agricultural produce, land settlement schemes that include irrigation, and rural electrification. To date, no attempt has been made to assess the gender-specific socioeconomic impacts of these individual programs and their combinations. It was hypothesized that the utilization of development program outputs will exert a gender-differential impact upon occupational and income status, but the magnitude and direction of the impacts remain to be determined. Path analysis was applied to estimate the model for each development program and their mixes for males and females separated. A multistage stratified sampling design was utilized. All of the development programs and their mixes exhibited significant effect of educational attainment upon participation in nonagricultural occupations. Rural electrification (RE) was the only program whose effect was positive; in combinations with education it accounted for 15% of the variation in occupation. Among the programs that were negatively related to male participation in nonagricultural occupations, the most important predictors were the land settlement (LS) and guarantee price scheme (GPS) programs. Each program contributed to over 1/5 of the variation in occupation net of educational attainment. RE was the only program that was not significantly related to female participation in nonhousehold occupations. All of the remaining programs exerted a positive effect upon occupation. 3 of these programs -- RE + LS, GPS, and LS + GPS -- were of almost equally high importance in predicting participation of females in nonhousehold occupations, and in

  2. Influence of pesticide regulation on acute poisoning deaths in Sri Lanka.

    PubMed Central

    Roberts, Darren M.; Karunarathna, Ayanthi; Buckley, Nick A.; Manuweera, Gamini; Sheriff, M. H. Rezvi; Eddleston, Michael

    2003-01-01

    OBJECTIVES: To assess in a developing Asian country the impact of pesticide regulation on the number of deaths from poisoning. These regulations, which were implemented in Sri Lanka from the 1970s, aimed to reduce the number of deaths - the majority from self-poisoning - by limiting the availability and use of highly toxic pesticides. METHODS: Information on legislative changes was obtained from the Ministry of Agriculture, national and district hospital admission data were obtained from the Sri Lanka Health Statistics Unit, and individual details of deaths by pesticide poisoning were obtained from a manual review of patients' notes and intensive care unit records in Anuradhapura. FINDINGS: Between 1986 and 2000, the total national number of admissions due to poisoning doubled, and admissions due to pesticide poisoning increased by more than 50%. At the same time, the case fatality proportion (CFP) fell for total poisonings and for poisonings due to pesticides. In 1991_92, 72% of pesticide-induced deaths in Anuradhapura were caused by organophosphorus (OP) and carbamate pesticides - in particular, the WHO class I OPs monocrotophos and methamidophos. From 1991, the import of these pesticides was reduced gradually until they were banned for routine use in January 1995, with a corresponding fall in deaths. Unfortunately, their place in agricultural practice was taken by the WHO class II organochlorine endosulfan, which led to a rise in deaths from status epilepticus - from one in 1994 to 50 in 1998. Endosulfan was banned in 1998, and over the following three years the number of endosulfan deaths fell to three. However, at the end of the decade, the number of deaths from pesticides was at a similar level to that of 1991, with WHO class II OPs causing the most deaths. Although these drugs are less toxic than class I OPs, the management of class II OPs remains difficult because they are, nevertheless, still highly toxic, and their toxicity is exacerbated by the paucity

  3. Change in Dengue and Japanese Encephalitis Seroprevalence Rates in Sri Lanka

    PubMed Central

    Jeewandara, Chandima; Gomes, Laksiri; Paranavitane, S. A.; Tantirimudalige, Mihiri; Panapitiya, Sumedha Sandaruwan; Jayewardene, Amitha; Fernando, Samitha; Fernando, R. H.; Prathapan, Shamini

    2015-01-01

    Background Sri Lanka has been affected by epidemics of dengue infections for many decades and the incidence and severity of dengue infections have been rising each year. Therefore, we investigated the age stratified seroprevalence of dengue infections in order to facilitate future dengue vaccine strategies. In addition, since the symptomatic dengue infections have increased during the past few decades, we also investigated the possible association with Japanese Encephalitis Virus (JEV) antibody seropositivity with symptomatic dengue in a community cohort in Sri Lanka. Methods 1689 healthy individuals who were attending a primary health care facility were recruited. Dengue and JEV antibody status was determined in all individuals and JEV vaccination status was recorded. Results 1152/1689 (68.2%) individuals were seropositive for dengue and only 133/1152 (11.5%) of them had been hospitalized to due to dengue. A significant and positive correlation was observed for dengue antibody seropositivity and age in children (Spearmans R = 0.84, p = 0.002) and in adults (Spearmans R = 0.96, p = 0.004). We observed a significant rise in the age stratified seroprevalence rates in children over a period of 12 years. For instance, in year 2003 the annual seroconversion rate was 1.5% per annum, which had risen to 3.79% per annum by 2014. We also found that both adults (p<0.001) and in children (p = 0.03) who were hospitalized due to dengue were more likely to be seropositive for JEV antibodies. However, 244 (91.4%) of adults who were seropositive for JEV had not had the JEV vaccine. Conclusions Dengue seroprevalence rates have risen significantly over the last 12 years in Sri Lanka, possibly due to increased transmission. As individuals who were hospitalized due to dengue were more likely to be seropositive for JEV, the possibility of cross-reactive assays and/or of JEV infection on immunity to the DENV and clinical disease severity should be further investigated. PMID:26696417

  4. Selling cheap sex and seashells.

    PubMed

    West, J

    1993-03-01

    Sri Lanka became known as a gay paradise with the advent of tourism in the late 1970s. UNICEF estimates that up to 15,000 boys in Sri Lanka may engage in homosexual prostitution. Nearly 400,000 tourists visited Sri Lanka in 1992, 50,000 of them British. The probable increase of high risk sexual contacts between tourists and Sri Lankan youths worries the government's health department. By early 1993, there were only 22 cases of AIDS and 65 people who tested HIV positive. But the government's chief venereologist says there are around 200,000 cases of sexually transmitted diseases each year, and it is estimated that as many as 2500 Sri Lankans are HIV positive. In a population of 17 million, this figure is small, but it represents an increase of 300% in just over a year. The parallels with nearby Thailand, where HIV spread explosively, are ominous. Unfortunately, cultural taboos make sex education difficult. A UNICEF doctor described the first television commercials about AIDS as ridiculous. Ignorance about AIDS is almost total. Most boy prostitutes have heard of AIDS but few use condoms and none realize that the disease kills. Organizations like Save the Children Fund recognize the magnitude of the problem but admit that reaching the beach boys, who are financially independent, is difficult. In an attempt to attack the problem, 2 social organizations compiled a list of beach boys in Hikkaduwa, the most popular tourist resort, and invited them for counselling and voluntary AIDS testing, but no one showed up. PMID:12286737

  5. Mirror mounts designed for the Advanced Photon Source SRI-CAT

    SciTech Connect

    Shu, D.; Benson, C.; Chang, J.

    1997-09-01

    Use of a mirror for beamlines at third-generation synchrotron radiation facilities, such as the Advanced Photon Source (APS) at Argonne National laboratory, has many advantages. A mirror as a first optical component provides significant reduction in the beam peak heat flux and total power on the downstream monochromator and simplifies the bremsstrahlung shielding design for the beamline transport. It also allows one to have a system for multibeamline branching and switching. More generally, a mirror is used for beam focusing and/or low-pass filtering. Six different mirror mounts have been designed for the SRI-CAT beamlines. Four of them are designed as water-cooled mirrors for white or pink beam use, and the other two are for monochromatic beam use. Mirror mount designs, including vacuum vessel structure and precision supporting stages, are presented in this paper.

  6. Impacts of the 2004 Indian ocean tsunami on the southwest coasts of Sri Lanka

    USGS Publications Warehouse

    Morton, Robert A.; Goff, John A.; Nichol, Scott L.

    2007-01-01

    The 2004 Indian Ocean tsunami caused major landscape changes along the southwest coasts of Sri Lanka that were controlled by the flow, natural topography and bathymetry, and anthropogenic modifications of the terrain. Landscape changes included substantial beach erosion and scouring of return-flow channels near the beach, and deposition of sand sheets across the narrow coastal plain. In many areas tsunami deposits also included abundant building rubble due to the extensive destruction of homes and businesses in areas of dense development. Trim lines and flow directions confirmed that shoreline orientation and wave refraction from embayments and rock-anchored headlands locally focused the flow and amplified the inundation. Tsunami deposits were 1 to 36 cm thick but most were less than 25 cm thick. Deposit thickness depended partly on antecedent topography. The deposits were composed of coarse to medium sand organized into a few sets of plane parallel laminae that exhibited overall upward fining and landward thinning trends.

  7. Housing anxiety and multiple geographies in post-tsunami Sri Lanka.

    PubMed

    Boano, Camillo

    2009-10-01

    Tsunami intervention has been an extraordinary and unprecedented relief and recovery operation. This article underlines the complexities posed by shelter and housing intervention in post-tsunami Sri Lanka, revealing a pragmatic, reductionist approach to shelter and housing reconstruction in a contested and fragmented environment. Competition, housing anxiety and buffer zone implementation have resulted in compulsory villagisation inland, stirring feelings of discrimination and tension, and becoming major obstacles to equitable rebuilding of houses and livelihoods. A new tsunami geography has been imposed on an already vulnerable conflict-based geography, in which shelter has been conceived as a mono-dimensional artefact. An analysis of the process and outcomes of temporary and permanent post-tsunami housing programmes yields information about the extent to which shelter policies and programmes serve not only physical needs but 'higher order' objectives for a comprehensive and sustainable recovery plan. PMID:19459904

  8. Simulation of the SRI International test Gun-27 using the PAGOSA code

    SciTech Connect

    Jacoby, J.J.

    1997-06-23

    SRI International conducted a set of impact tests with flat disks hitting water-filled chemical submunitions. One of these tests, called Gun-27, involved a 595 gram disk hitting the side of a submunition at 200 m/s. This test was simulated using the PAGOSA code with a materials model that was a good overall match to the data, and with a sequence of five mesh sizes. It was found that when a mesh was used which had at least five cells across the wall of the submunition, PAGOSA was able to provide reasonably satisfactory agreement with the test results, except for the partial fracture of a welded joint. One feature of the test that was reproduced very well by the simulation that used the finest mesh was the fracture of the diaphragm around its edge. Results are compared for all five simulations so that trends can be seen.

  9. An evaluation of the undergraduate teaching programme in ophthalmology in Sri Lanka and Malaysia.

    PubMed

    Dias, P L

    1987-07-01

    The knowledge and clinical and minor surgical skills acquired by 257 medical students in three universities in Sri Lanka and Malaysia were assessed by a questionnaire after they had completed their training period in ophthalmology. This study showed that many medical students graduating from these universities lacked the basic clinical and minor surgical skills essential for a doctor practising in a community in south-east Asia. The responses also indicated that teaching by consultants in all three universities was inadequate and due to these inadequacies the students requested that the duration of their training period be doubled. Ophthalmology is an important component of clinical practice and proper education in this subject is important. An urgent revision of the aims and objectives of the curriculum in ophthalmology is essential to place greater emphasis on this important and much neglected subject, for which very little curricular time is allotted. PMID:3626901

  10. Pure gonadal dysgenesis (Swyer syndrome) due to microdeletion in the SRY gene: a case report.

    PubMed

    Mutlu, Gül Yesiltepe; Kırmızıbekmez, Heves; Aydın, Hatip; Çetiner, Handan; Moralıoğlu, Serdar; Celayir, Ayşenur Cerrah

    2015-01-01

    46,XY complete gonadal dysgenesis (Swyer syndrome) is a rare cause of disorder of sexual development. This syndrome is caused by a defect in the determination of sex during embryogenesis and is characterised with female external genitalia, normal or rudimentary uterus, and streak gonads, despite the presence of the 46,XY karyotype. Most of the studied cases presented with leak of secondary sex characteristics and primary amenorrhea during adolescence. Laboratory findings reveal hypergonadotropic hypogonadism. Herein we present the case of a female with a 46,XY karyotype who was admitted with delayed puberty and detected to have a microdeletion in the SRY gene and diagnosed to have Swyer syndrome. We highlight the importance of karyotype analysis in patients with delayed puberty and primary amenorrhea. Once the diagnosis of 46,XY complete gonadal dysgenesis is established, early laparoscopic removal of the dysgenetic gonads is crucial to prevent the development of gonadal malignancy. PMID:25153220

  11. The problem of privacy in transcultural research: reflections on an ethnographic study in Sri Lanka.

    PubMed

    Monshi, Bardia; Zieglmayer, Verena

    2004-01-01

    Western laws and codes of ethics frequently require that private health information be treated confidentially. However, cross-cultural research shows that it is not always easy to determine what members of a culture consider to be private or how they wish private information to be handled. This article begins by presenting an ethnographic study of patient-healer relationships in Sri Lanka; researchers were surprised to find that participants' views of health and privacy differed greatly from typical Western views, and that the privacy protections they had put in place caused discomfort among participants. Building on this ethics case study, the article explores two main questions. First, can a single definition of privacy possibly do justice to the cultural variations that exist, or does a conceptual definition inevitably run the risk of ethnocentrism? Second, to what extent is strict compliance with research regulations or ethics codes ethically justifiable when following the rules will obviously cause unease in international participants? PMID:16622990

  12. Municipal solid waste management in the Southern Province of Sri Lanka: Problems, issues and challenges

    SciTech Connect

    Vidanaarachchi, Chandana K. . E-mail: c.vidanaarachchi@civenv.unimelb.edu.au; Yuen, Samuel T.S.; Pilapitiya, Sumith

    2006-07-01

    This paper describes the problems, issues and challenges faced by Sri Lanka based on the outcome of a recent study conducted in the country's Southern Province. The study consists of a public survey, discussions with local authority staff involved in waste management, discussions with Provincial Council and Government officials, dialogue with local politicians, review of documents and field observations. The study revealed that only 24% of the households have access to waste collection and that in rural areas it was less than 2%. A substantial number of households in areas without waste collection expect local authorities to collect their waste. The study also showed that most sites in the province are under capacity to handle any increased demand. Urgent and immediate improvement of the waste disposal sites is necessary to meet the current demand for improved waste collection. The study also revealed that there is a high willingness of people for home composting.

  13. Effect of soil carbohydrates on nutrient availability in natural forests and cultivated lands in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Ratnayake, R. R.; Seneviratne, G.; Kulasooriya, S. A.

    2013-05-01

    Carbohydrates supply carbon sources for microbial activities that contribute to mineral nutrient production in soil. Their role on soil nutrient availability has not yet been properly elucidated. This was studied in forests and cultivated lands in Sri Lanka. Soil organic matter (SOM) fractions affecting carbohydrate availability were also determined. Soil litter contributed to sugars of plant origin (SPO) in croplands. The negative relationship found between clay bound organic matter (CBO) and glucose indicates higher SOM fixation in clay that lower its availability in cultivated lands. In forests, negative relationships between litter and sugars of microbial origin (SMO) showed that litter fuelled microbes to produce sugars. Fucose and glucose increased the availability of Cu, Zn and Mn in forests. Xylose increased Ca availability in cultivated lands. Arabinose, the main carbon source of soil respiration reduced the P availability. This study showed soil carbohydrates and their relationships with mineral nutrients could provide vital information on the availability of limiting nutrients in tropical ecosystems.

  14. Secondary phosphate mineralization in a karstic environment in Central Sri Lanka

    NASA Astrophysics Data System (ADS)

    Dahanayake, Kapila; Subasinghe, S. M. N. D.

    1989-07-01

    At Eppawala in central Sri Lanka secondary phosphate mineralization is intimately associated with laminated fabrics within depressions (sinkholes and smaller cavities) formed in the thick weathering profiles of a hilly terrain underlain by a Precambrian apatite-bearing formation. The lowermost levels of the profile show extensive zones of leaching where derived apatite crystals occur within fine-grained, laminated stromatolite sequences. The stromatolitic groundmass, which diagenetically formed by percolating oxygenated phosphate and carbonate-rich groundwaters, is impregnated by the phosphate minerals francolite and collophane. Scanning electron microscopy (SEM) reveals that fine filaments, characteristic of microorganisms, are associated with the secondary phosphate mineralization. Continuous degradation and fragmentation of the stromatolitic mat has produced pellets, peloids, and intraclasts all enriched in secondary apatite. Degrading recrystallization around the edges of the primary apatite crystals has developed coated grains. The widespread occurrence of phosphate-enriched allochems in stromatolitic groundmasses is a unique development of a modern phosphorite in a karstic environment.

  15. Mirror mounts designed for the Advanced Photon Source SRI-CAT

    NASA Astrophysics Data System (ADS)

    Shu, D.; Benson, C.; Chang, J.; Barraza, J.; Kuzay, T. M.; Alp, E. E.; Sturhahn, W.; Lai, B.; McNulty, I.; Randall, K.; Srajer, G.; Xu, Z.; Yun, W.

    1997-07-01

    Use of a mirror for beamlines at third-generation synchrotron radiation facilities, such as the Advanced Photon Source (APS) at Argonne National Laboratory, has many advantages. [Yun et al., Rev. Sci. Instrum. 67(9)(1996)CD-ROM] A mirror as a first optical component provides significant reduction in the beam peak heat flux and total power on the downstream monochromator and simplifies the bremsstrahlung shielding design for the beamline transport. It also allows us to have a system for multibeamline branching and switching. More generally, a mirror is used for beam focusing and/or low-pass filtering. Six different mirror mounts have been designed for the SRI-CAT beamlines. Four of them are designed as water-cooled mirrors for white or pink beam use, and the other two are for monochromatic beam use. Mirror mount designs, including vacuum vessel structure and precision supporting stages, are presented in this paper.

  16. Chronic kidney disease of unknown aetiology and ground-water ionicity: study based on Sri Lanka.

    PubMed

    Dharma-Wardana, M W C; Amarasiri, Sarath L; Dharmawardene, Nande; Panabokke, C R

    2015-04-01

    High incidence of chronic kidney disease of unknown aetiology (CKDU) in Sri Lanka is shown to correlate with the presence of irrigation works and rivers that bring-in 'nonpoint source' fertilizer runoff from intensely agricultural regions. We review previous attempts to link CKDU with As, Cd and other standard toxins. Those studies (e.g. the WHO-sponsored study), while providing a wealth of data, are inconclusive in regard to aetiology. Here, we present new proposals based on increased ionicity of drinking water due to fertilizer runoff into the river system, redox processes in the soil and features of 'tank'-cascades and aquifers. The consequent chronic exposure to high ionicity in drinking water is proposed to debilitate the kidney via a Hofmeister-type (i.e. protein-denaturing) mechanism. PMID:25119535

  17. Dataset for an analysis of tourism and economic growth: A study of Sri Lanka.

    PubMed

    Kumar, Ronald Ravinesh; Stauvermann, Peter Josef

    2016-09-01

    We use the sample from 1978 to 2014 for the paper (doi:10.1016/j.tmp.2016.05.005). The data on GDP at constant 2005 USD (US dollar), and the gross fixed capital formation at constant 2005 USD are extracted from the World Bank (2015). The labour stock which includes direct and indirect employment and the tourism receipts (in USD) are sourced from the Sri Lanka Tourism Development Authority (http://www.sltda.lk/statistics). Tourism receipts as a per cent of GDP is used to measure tourism demand. The capital stock data is computed using perpetual inventory method, where a depreciation rate of 8 per cent is assumed with the initial capital stock as 1.05 times the GDP of 1969 at constant 2005 USD. The output per worker and capital per worker is computed by dividing the GDP and capital stock by the labour stock, respectively. PMID:27508224

  18. Determinants of contraceptive method choice in Sri Lanka: an update of a 1987 survey.

    PubMed

    Malhotra, A; Thapa, S

    1991-09-01

    This 1987 update study of the sociocultural and demographic determinants of contraceptive method choice in Sri Lanka reveals a striking consistency with previous investigations of the same issue. In 1975 and 1982, researchers conducted similar studies of the determinants of contraceptive method choice. These studies showed that method choice was primarily a function of demographic factors related to the couple's family-building stages rather than socioeconomic factors, suggesting that in Sri Lanka there were few socioeconomic barriers to accessibility and choice of contraceptive methods. For the update, researchers analyzed the data from the 1987 Demographic and Health Survey, a sample which included 5,449 currently married women between the ages of 15-49. As in the previous studies, the 1987 study four possible outcomes of contraceptive choice: not currently using a method, using a traditional method, using a temporary modern method, and sterilization. The researchers employed a multinominal logistic model as the analytical technique. The results of the analysis reveal a remarkable consistency with the previous studies. Both demographic and socioeconomic factors were important determinants of contraceptive use, evident in the fact that those who use contraception are not only motivated by their family-building stage, but also more likely to be urban, Sinhalese, and better educated. However, the study also found that family-cycle goals, rather than socioeconomic factors, continue to have the greatest influence over method choice, which explains the fact that there is a virtual lack of differentials among users of temporary modern and traditional methods. These findings suggest that government programs have not succeeded in promoting the sue of temporary modern methods of contraception. PMID:12284856

  19. Strength of fertility motivation: its effects on contraceptive use in rural Sri Lanka.

    PubMed

    Retherford, R D; Thapa, S; De Silva, V

    1989-12-01

    Sri Lanka's Rural Family Planning Survey (RFPS) was done between August of 1985 and February of 1986 by the Family Planning Association with the aid of Family Health International. A 2-stage stratified random sample design was used with probability proportional to size. 3253 interviews took place with currently married women age 20-44. The sample covered 30 rural villages but is not representative of rural Sri Lanka. The use of traditional and modern contraceptive methods is the dependent variable. Traditional methods include the "safe period method" and withdrawal. Sterilized women were excluded. The main independent variable is strength of fertility motivation. The mean desired family size is shown by socioeconomic and demographic characteristics for nonpregnant, fecund, currently married women age 20-44 who report relative preference intensity. Desired family size increases with the duration of marriage, age, and the number of living children. Desired family size is lower for more educated women. Contraceptive usage rates are shown for broad groups of methods. Overall use does not vary much by age, marital duration, number of children living, or age at 1st marriage. The more educated women have higher usage rates of traditional methods as do the more wealthy. Use of modern temporary methods goes down as wealth and education increase. For 5 of the 8 independent variables, there seems to be a "trade-off" between modern temporary methods and traditional methods. 2 alternative logistic models are included, based on relative preference intensity. Estimates of the probability of using contraception by each independent variable shown, the number of living children tends to increase contraceptive use up to about 4 and to decrease it at higher numbers, and age at 1st marriage has a slight negative effect on the use of contraception. PMID:12342629

  20. Mitigation of Sri Lanka Island Effects in Colombo Sounding Data during DYNAMO

    NASA Astrophysics Data System (ADS)

    Ciesielski, P. E.; Johnson, R. H.; Yoneyama, K.

    2013-12-01

    During the Dynamics of the MJO (DYNAMO) field campaign, upper-air soundings were launched at Colombo, Sri Lanka as part of the enhanced northern sounding array (NSA) of the experiment. The Colombo soundings were affected at low-levels by diurnal heating of this large island and by flow blocking due to elevated terrain to the east of the Colombo site. Because of the large spacing between sounding sites, these small-scale effects are aliased onto the larger scale impacting analyses and atmospheric budgets over the DYNAMO NSA. To mitigate these local island effects on the large-scale budgets, a procedure was designed which uses ECMWF-analyzed fields in the vicinity of Sri Lanka to estimate open-ocean conditions (i.e, as if this island were not present). These 'unperturbed' ECMWF fields at low-levels are then merged with observed Colombo soundings. This procedure effectively mutes the blocking effects and large diurnal cycle observed in the low-level Colombo fields. In westerly flow regimes, adjusted Colombo winds increase the low-level westerlies by 2-3 m/s with a similar increase of the low-level easterlies in easterly flow regimes. In general, over the NSA the impact of the adjusted Colombo winds results in more low-level divergence (convergence), more mid-level subsidence (rising motion) and reduced (increased) rainfall during the westerly (easterly) wind regimes. In comparison to independent TRMM rainfall estimates, both the mean budget-derived rainfall and its temporal correlation are improved by using the adjusted Colombo soundings. In addition, use of the 'unperturbed' fields result in a more realistic moisture budget analyses, both in its diurnal cycle and during the build-up phase of the November MJO when a gradual deepening of apparent drying was observed. Overall, use of the adjusted Colombo soundings appears to have a beneficial impact on the NSA analyses and budgets.

  1. Precipitant profile of acute heart failure: experience of a tertiary level cardiac centre in Sri Lanka

    PubMed Central

    Matthias, Anne Thushara; Ekanayaka, Ruvan

    2013-01-01

    Introduction and objectives Heart failure (HF) is a common cause of hospitalisation in most countries. Data on acute precipitants of HF and hospitalisation is not available in Sri Lanka. Background and methods A prospective study of 100 sequential admissions with HF to the cardiology unit (National Hospital of Sri Lanka) to describe the precipitants and clinical outcome of HF. Results Fifty-eight male and 42 female admissions were studied. Mean age was 60.66 years. Mean hospital stay was 5.5(SD 4.6) days. Sixty had de novo HF and 40 had pre-existing HF. The most common identifiable precipitants were acute ischaemia 37 (37%), anaemia 41 (41%), respiratory tract infection 10 (10%), arrhythmia 11 (11%), worsening renal function 11 (11%) and alcohol 5 (5.7%). Non-adherence to medication 4 (4.6%), smoking 3 (3.9%), exposure to environmental stress 3 (3.4%) and uncontrolled hypertension 1 (1%) were also observed as precipitants. The most common arrhythmia was atrial fibrillation. Out of 34 patients in whom angiotensin-converting enzyme inhibitors or angiotensin-converting enzyme receptor blockers were indicated, 11% were not on the drug. Among 29 patients in whom spironolactone was indicated, seven patients were not on the drug. Conclusions Most precipitating factors of HF are preventable. Early identification and prevention of anaemia, preventing respiratory tract infection by vaccination, aggressive revascularisation for patients with ischaemia, monitoring of renal functions, and patient education regarding drug and diet compliance, would reduce the number of admissions. PMID:27326091

  2. Species Composition and Diversity of Malaria Vector Breeding Habitats in Trincomalee District of Sri Lanka

    PubMed Central

    Gunathilaka, Nayana; Abeyewickreme, Wimaladharma; Hapugoda, Menaka; Wickremasinghe, Rajitha

    2015-01-01

    Introduction. Mosquito larval ecology is important in determining larval densities and species assemblage. This in turn influences malaria transmission in an area. Therefore, understanding larval habitat ecology is important in designing malaria control programs. Method. Larval surveys were conducted in 20 localities under five sentinel sites (Padavisiripura, Gomarankadawala, Thoppur, Mollipothana, and Ichchallampaththu) in Trincomalee District, Eastern Province of Sri Lanka, between June 2010 and July 2013. The relationship between seven abiotic variables (temperature, pH, conductivity, Total Dissolved Solid (TDS), turbidity, Dissolved Oxygen (DO), and salinity) was measured. Results. A total of 21,347 anophelines were recorded representing 15 species. Anopheles subpictus 24.72% (5,278/21,347) was the predominant species, followed by 24.67% (5,267/21,347) of An. nigerrimus and 14.56% (3,109/21,347) of An. peditaeniatus. A total of 9,430 breeding habitats under twenty-one categories were identified. An. culcicifacies was noted to be highest from built wells (20.5%) with high salinity (1102.3 ± 81.8 mg/L), followed by waste water collections (20.2%) having low DO levels (2.85 ± 0.03 mg/L) and high TDS (1,654 ± 140 mg/L). Conclusion. This study opens an avenue to explore new breeding habitats of malaria vectors in the country and reemphasizes the requirement of conducting entomological surveillance to detect potential transmission of malaria in Sri Lanka under the current malaria elimination programme. PMID:26583136

  3. Chronic kidney disease of unknown aetiology in Sri Lanka: is cadmium a likely cause?

    PubMed Central

    2011-01-01

    Background The rising prevalence of chronic kidney disease (CKD) and subsequent end stage renal failure necessitating renal replacement therapy has profound consequences for affected individuals and health care resources. This community based study was conducted to identify potential predictors of microalbuminuria in a randomly selected sample of adults from the North Central Province (NCP) of Sri Lanka, where the burden of CKD is pronounced and the underlying cause still unknown. Methods Exposures to possible risk factors were determined in randomly recruited subjects (425 females and 461 males) from selected areas of the NCP of Sri Lanka using an interviewer administered questionnaire. Sulphosalicylic acid and the Light Dependent Resister microalbumin gel filtration method was used for initial screening for microalbuminuria and reconfirmed by the Micral strip test. Results Microalbumnuria was detected in 6.1% of the females and 8.5% of the males. Smoking (p < 0.001), alcohol use (p = 0.003), hypertension (p < 0.001), diabetes (p < 0.001), urinary tract infection (UTI) (p = 0.034) and consumption of water from wells in the fields (p = 0.025) were associated with microalbuminuria. In the binary logistic regression analysis, hypertension, diabetes mellitus, UTI, drinking well water in the fields, smoking and pesticide spraying were found to be significant predictors of microalbuminuria. Conclusions Hypertension, diabetes mellitus, UTI, and smoking are known risk factors for microalbuminuria. The association between microalbuminuria and consumption of well water suggests an environmental aetiology to CKD in NCP. The causative agent is yet to be identified. Investigations for cadmium as a potential causative agent needs to be initiated. PMID:21726464

  4. Addressing domestic violence through antenatal care in Sri Lanka's plantation estates: Contributions of public health midwives.

    PubMed

    Infanti, Jennifer J; Lund, Ragnhild; Muzrif, Munas M; Schei, Berit; Wijewardena, Kumudu

    2015-11-01

    Domestic violence in pregnancy is a significant health concern for women around the world. Globally, much has been written about how the health sector can respond effectively and comprehensively to domestic violence during pregnancy via antenatal services. The evidence from low-income settings is, however, limited. Sri Lanka is internationally acknowledged as a model amongst low-income countries for its maternal and child health statistics. Yet, very little research has considered the perspectives and experiences of the key front line health providers for pregnant women in Sri Lanka, public health midwives (PHMs). We address this gap by consulting PHMs about their experiences identifying and responding to pregnant women affected by domestic violence in an underserved area: the tea estate sector of Badulla district. Over two months in late 2014, our interdisciplinary team of social scientists and medical doctors met with 31 estate PHMs for group interviews and a participatory workshop at health clinics across Badulla district. In the paper, we propose a modified livelihoods model to conceptualise the physical, social and symbolic assets, strategies and constraints that simultaneously enable and limit the effectiveness of community-based health care responses to domestic violence. Our findings also highlight conceptual and practical strategies identified by PHMs to ensure improvements in this complex landscape of care. Such strategies include estate-based counselling services; basic training in family counselling and mediation for PHMs; greater surveillance of abusive men's behaviours by male community leaders; and performance evaluation and incentives for work undertaken to respond to domestic violence. The study contributes to international discussions on the meanings, frameworks, and identities constructed at the local levels of health care delivery in the global challenge to end domestic violence. In turn, such knowledge adds to international debates on the roles

  5. Is Hiding Foot and Mouth Disease Sensitive Behavior for Farmers? A Survey Study in Sri Lanka.

    PubMed

    Gunarathne, Anoma; Kubota, Satoko; Kumarawadu, Pradeep; Karunagoda, Kamal; Kon, Hiroichi

    2016-02-01

    Foot and mouth disease (FMD) has a long history in Sri Lanka and was found to be endemic in various parts of the country and constitutes a constant threat to farmers. In Sri Lanka, currently there is no regular, nationwide vaccination programme devised to control FMD. Therefore, improving farmers' knowledge regarding distinguishing FMD from other diseases and ensuring prompt reporting of any suspicion of FMD as well as restricting movement of animals are critical activities for an effective FMD response effort. Therefore, the main purpose of this study was to clarify the relationship between farmers' knowledge levels and their behaviors to establish a strategy to control FMD. In our study, item count technique was applied to estimate the number of farmers that under-report and sell FMD-infected animals, although to do so is prohibited by law. The following findings were observed: about 63% of farmers have very poor knowledge of routes of FMD transmission; 'under-reporting' was found to be a sensitive behavior and nearly 23% of the farmers were reluctant to report FMD-infected animals; and 'selling FMD-infected animals' is a sensitive behavior among high-level knowledge group while it is a non-sensitive behavior among the low-level knowledge group. If farmers would understand the importance of prompt reporting, they may report any suspected cases of FMD to veterinary officials. However, even if farmers report honestly, they do not want to cull FMD-infected animals. Thus, education programs should be conducted not only on FMD introduction and transmission, but also its impact. Furthermore, consumers may criticize the farmers for culling their infected animals. Hence, not only farmers, but also consumers need to be educated on the economic impact of FMD and the importance of controlling an outbreak. If farmers have a high knowledge of FMD transmission, they consider selling FMD-infected animals as a sensitive behavior. Therefore, severe punishment should be levied for

  6. Collective trauma in northern Sri Lanka: a qualitative psychosocial-ecological study

    PubMed Central

    Somasundaram, Daya

    2007-01-01

    Background Complex situations that follow war and natural disasters have a psychosocial impact on not only the individual but also on the family, community and society. Just as the mental health effects on the individual psyche can result in non pathological distress as well as a variety of psychiatric disorders; massive and widespread trauma and loss can impact on family and social processes causing changes at the family, community and societal levels. Method This qualitative, ecological study is a naturalistic, psychosocial ethnography in Northern Sri Lanka, while actively involved in psychosocial and community mental health programmes among the Tamil community. Participatory observation, key informant interviews and focus group discussion with community level relief and rehabilitation workers and government and non-governmental officials were used to gather data. The effects on the community of the chronic, man-made disaster, war, in Northern Sri Lanka were compared with the contexts found before the war and after the tsunami. Results Fundamental changes in the functioning of the family and the community were observed. While the changes after the tsunami were not so prominent, the chronic war situation caused more fundamental social transformations. At the family level, the dynamics of single parent families, lack of trust among members, and changes in significant relationships, and child rearing practices were seen. Communities tended to be more dependent, passive, silent, without leadership, mistrustful, and suspicious. Additional adverse effects included the breakdown in traditional structures, institutions and familiar ways of life, and deterioration in social norms and ethics. A variety of community level interventions were tried. Conclusion Exposure to conflict, war and disaster situations impact on fundamental family and community dynamics resulting in changes at a collective level. Relief, rehabilitation and development programmes to be effective will

  7. Century scale climate change in the central highlands of Sri Lanka

    NASA Astrophysics Data System (ADS)

    Silva, J. De; J Sonnadara, D. U.

    2016-02-01

    In this study, an analysis of century scale climate trends in the central highlands of Sri Lanka is presented. Monthly rainfall and temperature records of the period 1869-2006 from five climatological stations were analyzed. The trend is calculated by the least square regression analysis and the significance of the observed trend is estimated using the Mann-Kendall statistic. The results clearly show that there is a statistically significant decrease in annual rainfall in the western slopes of the central highlands. Throughout the last century, the annual reduction of rainfall in Nuwara Eliya which is at an altitude of 1895 m was 5.2 mm/year. The decrease is largely due to the reduction in southwest monsoon rainfall which contributes to 75% of the total reduction. No significant change was observed on the eastern side of the central highlands which receives rainfall predominantly from the northeast monsoons. The mean annual temperature in the mountainous region shows a uniform increasing trend which is in line with the 100-year global temperature increase of 0.8 ± 0.2∘C. Kandy, which is at an altitude of 477 m and closely linked with the rainfall climatology of Nuwara Eliya, showed no significant change in the mean annual temperature. If the current trend continues, in another 100 years, western and eastern slopes of central highlands will receive the same amount of rainfall from the southwest monsoon and the northeast monsoon which will have far reaching consequences for Sri Lanka's economy and the ecology of the hill country.

  8. Characteristics of Narrow Bipolar Pulses observed from lightning in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Gunasekara, T. A. L. N.; Fernando, M.; Sonnadara, U.; Cooray, V.

    2016-02-01

    A detailed study on electric field characteristics of Narrow Bipolar Pulses (NBP) observed in Sri Lanka is presented here. NBPs analyzed in this work were recorded at a coastal location in the Southern part of Sri Lanka (Matara: 5.95 °N, 8.53 °E), from five highly active consecutive thunderstorm days during the month of May in 2013. The waveforms were recorded with a 10 ns resolution within a 100 ms time window. Both positive and negative NBPs were observed in this study with the negative type being the most frequent. Parameters presented in this study were the rise time (Tr), zero crossing time (Tz), the duration of slow front (Ts), the full width of half maximum (FWHM), the pulse duration and the ratio of amplitude of overshoot to the corresponding peak amplitude (Os/Pa). The corresponding average values of negative NBPs for these parameters were found to be 0.58 μs, 3.01 μs, 0.20 μs, 1.38 μs, 19.21 μs and 0.19 respectively. Similarly, for positive events corresponding values were 1.38 μs, 4.66 μs, 0.48 μs, 1.93 μs, 16.42 μs and 0.37 respectively. The above values conforms to a much narrower bipolar events when compared to previously reported values which is considered to be caused by the propagation effects of signals captured by the apparatus.

  9. Synchrotron radiation instrumentation collaborative access team SRI-CAT sector 4

    SciTech Connect

    1997-08-01

    The research objective for this sector of the Advanced Photon Source (APS) is the development of sources and applications of polarized x-rays covering the energy range from 0.5 to 50 keV. Both linearly and circularly polarized x-rays have been very successfully applied to the study of magnetic properties of materials. However, the applications have been limited due primarily to the lack of energy-tunable, high-brilliance x-ray beams with adjustable polarization properties. It is the authors` intention that this sector will to some extent ameliorate that situation. They are confident that optics can be fabricated to simultaneously provide a high-quality beam with adjustable polarization in the energy range above 5 keV using the standard undulator A as a source. That is not the case below 5 keV, and hence they are planning to develop and install a helical undulator that can generate beams of variable (linear or circular) polarization in this lower energy range. Magnetic circular dichroism, resonant and non-resonant magnetic x-ray scattering, and other polarization-dependent phenomena will be investigated using hard x-rays. Techniques similar to those described for the hard x-rays plus spatially resolved, spin-polarized photoemission studies will be developed and used with the intermediate energy x-rays. They have incorporated some features not directly related to polarization studies, which were not available elsewhere on SRI-CAT beamlines. One of those features is a large vacuum tank immediately downstream of the ratchet wall into which high heat load beamline components can be installed and tested. A second feature is a mirror capable of focusing the white beam for high heat flux optical-component development and other uses. The insertion-device development, polarization programs, and beamline component testing all fall well within the existing scope of the SRI CAT programs.

  10. Diffracted and pseudo-physical waves from spatially limited arrays using source-receiver interferometry (SRI)

    NASA Astrophysics Data System (ADS)

    Löer, Katrin; Meles, Giovanni Angelo; Curtis, Andrew; Vasconcelos, Ivan

    2014-02-01

    Source-receiver interferometry (SRI) refers to a technique to construct the Green's function between a source and a receiver using only energy that has travelled from and to surrounding boundaries of sources and receivers. If a background medium is perturbed, the corresponding interferometric equation can be expressed as the sum of eight terms, which result from the separation of the total wavefield into an unperturbed background field and the perturbed scattered field. Here, the contribution of each individual term is identified for singly diffracted waves using the methods of stationary phase analysis and waveform modelling. When the data acquisition boundary requirements for seismic interferometry are violated, non-physical energy is introduced into Green's function estimates. Our results show that four terms produce purely non-physical, non-stationary energy and that these can be suppressed, and that a combination of only two terms can be used to estimate diffracted wavefields robustly. One of the two terms is precisely that used in geophysical imaging schemes. A key result is that this term also produces non-physical energy, except when the integration boundaries are truncated to span only part of the medium's free surface: we thus show that in this sense, partial boundaries can be seen as a positive advantage for migration or imaging methods. The other term produces non-physical energy which nevertheless emulates physical energy; such energy is therefore called pseudo-physical. We present for the first time a complete mathematical derivation of this new category of energy complemented with illustrative examples. Overall, this work significantly enhances our understanding of how scattered wave SRI works.

  11. Programmatic Use of Molecular Xenomonitoring at the Level of Evaluation Units to Assess Persistence of Lymphatic Filariasis in Sri Lanka

    PubMed Central

    Rao, Ramakrishna U.; Samarasekera, Sandhya D.; Nagodavithana, Kumara C.; Punchihewa, Manjula W.; Dassanayaka, Tharanga D. M.; P. K. D, Gamini; Ford, Ethan; Ranasinghe, Udaya S. B.; Henderson, Ralph H.; Weil, Gary J.

    2016-01-01

    Background Sri Lanka’s Anti Filariasis Campaign distributed 5 rounds of mass drug administration (MDA with DEC plus albendazole) to all endemic regions in the country from 2002–2006. Post-MDA surveillance results have generally been encouraging. However, recent studies have documented low level persistence of Wuchereria bancrofti in Galle district based on comprehensive surveys that include molecular xenomonitoring (MX, detection of filarial DNA in mosquitoes) results. The purposes of this study were to demonstrate the use of MX in large evaluation units (EUs) and to field test different mosquito sampling schemes. Methodology/Principal Findings Galle district (population 1.1 million) was divided into two EUs. These included a coastal EU with known persistent LF and an inland EU with little persistent LF. Mosquitoes were systematically sampled from ~300 trap locations in 30 randomly selected clusters (health administrative units) per EU. Approximately 28,000 Culex quinquefasciatus were collected with gravid traps and tested for filarial DNA by qPCR. 92/625 pools (14.7%) from the coastal EU and 8/583 pools (1.4%) from the inland EU were positive for filarial DNA. Maximum likelihood estimates (MLE) for filarial DNA rates were essentially the same when the same number of mosquito pools were collected and tested from 75, 150, or 300 trap sites (range 0.61–0.78% for the coastal EU and 0.04–0.07% for the inland EU). The ability to use a smaller number of trap sites reduces the cost and time required for mosquito sampling. Conclusions/Significance These results suggest there is widespread persistence of W. bancrofti infection in the coastal Galle EU 8 years after the last round of MDA in 2006, and this is consistent with other data from the district. This study has shown that MX can be used by national programs to assess and map the persistence of W. bancrofti at the level of large EUs in areas with Culex transmission. PMID:27196431

  12. Prevalence of partial edentulousness among the patients reporting to the Department of Prosthodontics Sri Ramachandra University Chennai, India: An epidemiological study

    PubMed Central

    Madhankumar, Seenivasan; Mohamed, Kasim; Natarajan, Shanmuganathan; Kumar, V. Anand; Athiban, I.; Padmanabhan, T. V.

    2015-01-01

    Aims and Objectives: To determine the occurrence of various missing teeth pattern among the partial edentulous patients residing in Chennai who are undergoing treatment for the replacement of missing teeth in the Department of Prosthodontics, Sri Ramachandra University Chennai, India. Settings and Design: Study was undertaken from January 2014 to October 2014, and the design was a descriptive cross-sectional study. Materials and Methods: Five hundred and sixty-one persons aged between 13 and 87 years (267 males and 294 females) were selected, intraoral examination was done visually and results were recorded on specially designed clinical examination forms. Statistical Analysis: Data were analyzed using statistics SPSS 19.0 version (IBM India Private Limited Bangalore) to investigate the relationship between quantitative variables. Results: The results showed the patients with Kennedy's Class III were found to be the most prevalent among all the groups (55%). The most common modification in all the groups was Class III modification I (26%). It was also found that Kennedy's Class III was founded more in the age group of 31–40 with 54.4% in the maxillary arch and 47.2% in the mandibular arch. Conclusion: The findings of this study show that the Kennedy's Class III was the most commonly occurring and were found to be more predominant in the younger group of population. PMID:26538935

  13. Human used upper montane ecosystem in the Horton Plains, central Sri Lanka - a link to Lateglacial and early Holocene climate and environmental changes

    NASA Astrophysics Data System (ADS)

    Premathilake, Rathnasiri

    2012-09-01

    This study utilizes radiocarbon-dated pollen, spores, Sphagnum spp. macrofossils and total organic carbon proxies to examine variability of past climate, environment and human activity in montane rainforest, grassland and wetland of the Horton Plains (HP), central Sri Lanka since the Last Glacial Maximum (LGM). The LGM is largely characterized by grasslands and xerophytic herbs dominated open habitats. Arid-LGM punctuated climatic ameliorations, which took place in short episodes. Humans appear to have reached the HP ecosystem after 18,000 cal yrs BP occasionally. The first Intertropical Convergence Zone (ITCZ) induced changes in South West Monsoon (SWM) rains occurred at low latitudes between 16,200 and 15,900 cal yrs BP suggesting an onset of monsoon rains. After this event, monsoon rains weakened for several millennia except the period 13,700-13,000 cal yrs BP, but human activity seems to have continued with biomass burning and clearances by slash and burn. Very large size grass pollen grains, which are morphologically similar to pollen from closer forms of Oryza nivara, were found after 13,800 cal yrs BP. Early Holocene extreme and abrupt climate changes seem to have promoted the forms of O. nivara populations in association with humans. New data from the HP would therefore be most interesting to investigate the dispersal and use of domesticated rice in South Asia.

  14. Collective trauma in the Vanni- a qualitative inquiry into the mental health of the internally displaced due to the civil war in Sri Lanka

    PubMed Central

    2010-01-01

    Background From January to May, 2009, a population of 300,000 in the Vanni, northern Sri Lanka underwent multiple displacements, deaths, injuries, deprivation of water, food, medical care and other basic needs caught between the shelling and bombings of the state forces and the LTTE which forcefully recruited men, women and children to fight on the frontlines and held the rest hostage. This study explores the long term psychosocial and mental health consequences of exposure to massive, existential trauma. Methods This paper is a qualitative inquiry into the psychosocial situation of the Vanni displaced and their ethnography using narratives and observations obtained through participant observation; in depth interviews; key informant, family and extended family interviews; and focus groups using a prescribed, semi structured open ended questionnaire. Results The narratives, drawings, letters and poems as well as data from observations, key informant interviews, extended family and focus group discussions show considerable impact at the family and community. The family and community relationships, networks, processes and structures are destroyed. There develops collective symptoms of despair, passivity, silence, loss of values and ethical mores, amotivation, dependency on external assistance, but also resilience and post-traumatic growth. Conclusions Considering the severity of family and community level adverse effects and implication for resettlement, rehabilitation, and development programmes; interventions for healing of memories, psychosocial regeneration of the family and community structures and processes are essential. PMID:20667090

  15. Molecular delineation of the Y-borne Sry gene in the Formosan pangolin (Manis pentadactyla pentadactyla) and its phylogenetic implications for Pholidota in extant mammals.

    PubMed

    Yu, Hon-Tsen; Ma, Gwo-Chin; Lee, Dong-Jay; Chin, Shih-Chien; Tsao, Hsien-Shao; Wu, Sheng-Hai; Shih, Shu-Yi; Chen, Ming

    2011-01-01

    The systematic status of Pholidota has been a matter of debate, particularly regarding the apparent inconsistency between morphological and molecular studies. The Sry gene, a master regulator of male sex determination in eutherian mammals, has not yet been used for phylogenetic analyses of extant mammals. The objective of the present study was to clone and characterize the complete gene (1300 base pairs; bp) and amino acid sequences (229 residues) of Sry from the Formosan pangolin (Manis pentadactyla pentadactyla), a member of Pholidota. The Sry amino acid identity between pangolin and other reported species ranged from 42.5% (mouse, Mus musculus) to 84.1% (European hare, Lepus europaeus). Sequence conservation was primarily in the high motility group (HMG) box (234 bp), whereas homology outside the HMG box was low. The cloned Sry was mapped to the pangolin Y chromosome by fluorescence in situ hybridization (FISH); this was confirmed to be the first Y-borne molecular marker identified in Pholidota. Based on Bayesian phylogenetic analysis for Sry HMG sequences from 36 representative taxa, including the Formosan pangolin, Pholidota was more closely related to Carnivora than to Xenarthra, consistent with the emerging molecular tree inferred from markers not located on the Y chromosome. In conclusion, this study characterized the gene structure of Sry of the Formosan pangolin and provided insights into the phylogenetic position of Pholidota. PMID:20739052

  16. Transmission dynamics of Cryptosporidium infection in a natural population of non-human primates at Polonnaruwa, Sri Lanka.

    PubMed

    Ekanayake, Dilrukshi K; Welch, David Mark; Kieft, Rudo; Hajduk, Stephen; Dittus, Wolfgang P J

    2007-11-01

    Infections from Cryptosporidium parvum are of interest not only to public health, but also to wildlife conservation, particularly when humans and livestock encroach on nature and thereby increase the risk of cross-species transmissions. To clarify this risk, we used polymerase chain reaction to examine the hypervariable region of the C. parvum 18S rRNA gene in feces from three monkey species. Samples were isolated from regions where disease transmission between monkeys, livestock, and humans was likely (soiled habitat) or unlikely (clean habitat). Monkey individuals, their social groups, and different species shared multiple genotypes/isolates of C. parvum. Ecological and molecular analyses suggested that Cryptosporidium infection among Toque macaques in soiled habitats was mainly the bovine genotype C. parvum. Monkeys inhabiting clean habitat, particularly gray and purple-faced langurs, lacked Cryptosporidium species/types associated with bovines. Livestock apparently was a main source of infection for wild primates. PMID:17984333

  17. A Novel SRY Gene Mutation p.F109L in a 46,XY Female with Complete Gonadal Dysgenesis.

    PubMed

    Andonova, Silvia; Robeva, Ralitsa; Sirakov, Milko; Mainhard, Karela; Tomova, Analia; Ledig, Susanne; Kumanov, Philip; Savov, Alexey

    2015-01-01

    46,XY complete gonadal dysgenesis (CGD) is a disorder of sexual development that can result from different mutations in genes associated with sex determination. Patients are phenotypically females, and the disease is often diagnosed in late adolescence because of delayed puberty. Here, we present the clinical and molecular data of a 46,XY female CGD patient with gonadoblastoma with dysgerminoma and incidentally found inherited thrombophilia. The clinical significance of the described de novo SRY gene mutation c.325T>C (p.F109L) is discussed. This case report supports the critical role of the HGM domain in the SRY gene and the need of a multidisciplinary approach for CGD patients. PMID:26871559

  18. Village agroforestry systems and tree-use practices: A case study in Sri Lanka. Multipurpose tree species network research series

    SciTech Connect

    Wickramasinghe, A.

    1992-01-01

    Village agroforestry systems in Sri Lanka have evolved through farmers' efforts to meet their survival needs. The paper examines farmers' land-use systems and their perceptions of the role of trees in the villages of Bambarabedda and Madugalla in central Sri Lanka. The benefits of village agroforestry are diverse food, fuelwood, fodder, timber, and mulch, but food products are of outstanding importance. The ability of Artocarpus heterophyllus (the jackfruit tree) and Cocos nucifera (coconut) to ensure food security during the dry season and provide traditional foods throughout the year, as well as to grow in limited space, make them popular crops in the two study villages. The study recommends that further research precede the formulation of agricultural interventions and that efforts to promote improved tree varieties recognize farmers' practices and expressed needs.

  19. On the road to eliminate malaria in Sri Lanka: lessons from history, challenges, gaps in knowledge and research needs

    PubMed Central

    2014-01-01

    Malaria is one of the most important tropical diseases that has caused devastation throughout the history of mankind. Malaria eradication programmes in the past have had many positive effects but failed to wipe out malaria from most tropical countries, including Sri Lanka. Encouraged by the impressive levels of reduction in malaria case numbers during the past decade, Sri Lanka has launched a programme to eliminate malaria by year 2014. This article reviews the historical milestones associated with the malaria eradication programme that failed subsequently and the events that led to the launch of the ongoing malaria elimination plans at national-level and its strategies that are operational across the entire country. The existing gaps in knowledge are also discussed together with the priority areas for research to fill in these gaps that are posing as challenges to the envisaged goal of wiping out malaria from this island nation. PMID:24548783

  20. Homegardens as a multi-functional land-use strategy in Sri Lanka with focus on carbon sequestration.

    PubMed

    Mattsson, Eskil; Ostwald, Madelene; Nissanka, S P; Marambe, Buddhi

    2013-11-01

    This paper explores the concept of homegardens and their potential functions as strategic elements in land-use planning, and adaptation and mitigation to climate change in Sri Lanka. The ancient and locally adapted agroforestry system of homegardens is presently estimated to occupy nearly 15 % of the land area in Sri Lanka and is described in the scientific literature to offer several ecosystem services to its users; such as climate regulation, protection against natural hazards, enhanced land productivity and biological diversity, increased crop diversity and food security for rural poor and hence reduced vulnerability to climate change. Our results, based on a limited sample size, indicate that the homegardens also store significant amount of carbon, with above ground biomass carbon stocks in dry zone homegardens (n = 8) ranging from 10 to 55 megagrams of carbon per hectare (Mg C ha(-1)) with a mean value of 35 Mg C ha(-1), whereas carbon stocks in wet zone homegardens (n = 4) range from 48 to 145 Mg C ha(-1) with a mean value of 87 Mg C ha(-1). This implies that homegardens may contain a significant fraction of the total above ground biomass carbon stock in the terrestrial system in Sri Lanka, and from our estimates its share has increased from almost one-sixth in 1992 to nearly one-fifth in 2010. In the light of current discussions on reducing emissions from deforestation and forest degradation (REDD+), the concept of homegardens in Sri Lanka provides interesting aspects to the debate and future research in terms of forest definitions, setting reference levels, and general sustainability. PMID:23456780

  1. Use of Social Media in Facilitating Health Care Research Among Nursing and Allied Health Undergraduates in Sri Lanka.

    PubMed

    Silva, S N

    2016-01-01

    A mentoring program was designed to promote conduction, completion and dissemination of undergraduate research among Nursing and Allied Health students in Sri Lanka. Several social media platforms were used; mainly the Facebook, YouTube and Google Hangouts. Knowledge sharing, interaction and collaboration were promoted. Student motivation was also done. Research presentation skills and applying for conferences was also facilitated. Over 90% of the participated 262 students completed a research project and close to 50% presented them both locally and internationally. PMID:27332276

  2. Costs of Dengue Control Activities and Hospitalizations in the Public Health Sector during an Epidemic Year in Urban Sri Lanka

    PubMed Central

    Thalagala, Neil; Tissera, Hasitha; Palihawadana, Paba; Amarasinghe, Ananda; Ambagahawita, Anuradha; Wilder-Smith, Annelies; Shepard, Donald S.; Tozan, Yeşim

    2016-01-01

    Background Reported as a public health problem since the 1960s in Sri Lanka, dengue has become a high priority disease for public health authorities. The Ministry of Health is responsible for controlling dengue and other disease outbreaks and associated health care. The involvement of large numbers of public health staff in dengue control activities year-round and the provision of free medical care to dengue patients at secondary care hospitals place a formidable financial burden on the public health sector. Methods We estimated the public sector costs of dengue control activities and the direct costs of hospitalizations in Colombo, the most heavily urbanized district in Sri Lanka, during the epidemic year of 2012 from the Ministry of Health’s perspective. The financial costs borne by public health agencies and hospitals are collected using cost extraction tools designed specifically for the study and analysed retrospectively using a combination of activity-based and gross costing approaches. Results The total cost of dengue control and reported hospitalizations was estimated at US$3.45 million (US$1.50 per capita) in Colombo district in 2012. Personnel costs accounted for the largest shares of the total costs of dengue control activities (79%) and hospitalizations (46%). The results indicated a per capita cost of US$0.42 for dengue control activities. The average costs per hospitalization ranged between US$216–609 for pediatric cases and between US$196–866 for adult cases according to disease severity and treatment setting. Conclusions This analysis is a first attempt to assess the economic burden of dengue response in the public health sector in Sri Lanka. Country-specific evidence is needed for setting public health priorities and deciding about the deployment of existing or new technologies. Our results suggest that dengue poses a major economic burden on the public health sector in Sri Lanka. PMID:26910907

  3. Toxic polyneuropathy due to gingili oil contaminated with tri-cresyl phosphate affecting adolescent girls in Sri Lanka.

    PubMed

    Senanayake, N; Jeyaratnam, J

    1981-01-10

    An outbreak of acute polyneuropathy affected over 20 young females in Sri Lanka during 1977-78. The illness was restricted to girls attaining menarche and to women after childbirth. The cause of the neuropathy could be traced to tri-cresyl phosphate found as a contaminant in gingili oil. Contamination probably occurred during transport of the oil in containers previously used for storing mineral oils. PMID:6109132

  4. Seed-Mediated Gene Flow Promotes Genetic Diversity of Weedy Rice within Populations: Implications for Weed Management

    PubMed Central

    He, Zhuoxian; Jiang, Xiaoqi; Ratnasekera, Disna; Grassi, Fabrizio; Perera, Udugahapattuwage; Lu, Bao-Rong

    2014-01-01

    Increased infestation of weedy rice—a noxious agricultural pest has caused significant reduction of grain yield of cultivated rice (Oryza sativa) worldwide. Knowledge on genetic diversity and structure of weedy rice populations will facilitate the design of effective methods to control this weed by tracing its origins and dispersal patterns in a given region. To generate such knowledge, we studied genetic diversity and structure of 21 weedy rice populations from Sri Lanka based on 23 selected microsatellite (SSR) loci. Results indicated an exceptionally high level of within-population genetic diversity (He = 0.62) and limited among-population differentiation (Fst = 0.17) for this predominantly self-pollinating weed. UPGMA analysis showed a loose genetic affinity of the weedy rice populations in relation to their geographical locations, and no obvious genetic structure among populations across the country. This phenomenon was associated with the considerable amount of gene flow between populations. Limited admixture from STRUCTURE analyses suggested a very low level of hybridization (pollen-mediated gene flow) between populations. The abundant within-population genetic diversity coupled with limited population genetic structure and differentiation is likely caused by the considerable seed-mediated gene flow of weedy rice along with the long-distance exchange of farmer-saved rice seeds between weedy-rice contaminated regions in Sri Lanka. In addition to other effective weed management strategies, promoting the application of certified rice seeds with no weedy rice contamination should be the immediate action to significantly reduce the proliferation and infestation of this weed in rice ecosystems in countries with similar rice farming styles as in Sri Lanka. PMID:25436611

  5. Population genetics of the malaria vector Anopheles aconitus in China and Southeast Asia.

    PubMed

    Chen, Bin; Harbach, Ralph E; Walton, Catherine; He, Zhengbo; Zhong, Daibin; Yan, Guiyun; Butlin, Roger K

    2012-12-01

    Anopheles aconitus is a well-known vector of malaria and is broadly distributed in the Oriental Region, yet there is no information on its population genetic characteristics. In this study, the genetic differentiation among populations was examined using 140 mtDNA COII sequences from 21 sites throughout Southern China, Myanmar, Vietnam, Thailand, Laos and Sri Lanka. The population in Sri Lanka has characteristic rDNA D3 and ITS2, mtDNA COII and ND5 haplotypes, and may be considered a distinct subspecies. Clear genetic structure was observed with highly significant genetic variation present among population groups in Southeast Asia. The greatest genetic diversity exists in Yunnan and Myanmar population groups. All population groups are significantly different from one another in pairwise Fst values, except Northern Thailand with Central Thailand. Mismatch distributions and extremely significant F(s) values suggest that the populations passed through a recent demographic expansion. These patterns are discussed in relation to the likely biogeographic history of the region and compared to other Anopheles species. PMID:22982161

  6. Estimating dengue type reproduction numbers for two provinces of Sri Lanka during the period 2013-14.

    PubMed

    Sardar, Tridip; Sasmal, Sourav Kumar; Chattopadhyay, Joydev

    2016-02-17

    Dengue is an endemic disease in the southeast Asian country Sri Lanka. Two seasonal peaks of dengue incidence were observed every year since 2002 onwards. In this study, we formulate a 2-strain dengue model for analyzing the monthly seasonal dengue incidence data from 2 provinces of Sri Lanka during the period April 2013 to September 2014. The seasonality is incorporated in the model in terms of mosquito biting rate, which we assume to be time periodic. We estimated 2 primary reproduction numbers and the basic reproduction number in a periodic environment using dengue incidence data from the western and the central provinces of Sri Lanka. We also estimated different time-average type reproduction numbers from the model using the data from these 2 provinces. Using univariate sensitivity analysis, we measured the sensitivity of the time average reproduction number ([Formula: see text]) When we vary different parameters of the proposed dengue model, we find the transmission probability of human susceptibility to strain-I infection and the mosquito mortality rate parameters are the most sensitive parameters in dengue transmission in these 2 provinces. PMID:26646355

  7. Stochastic anomaly of methylome but persistent SRY hypermethylation in disorder of sex development in canine somatic cell nuclear transfer

    PubMed Central

    Jeong, Young-Hee; Lu, Hanlin; Park, Chi-Hun; Li, Meiyan; Luo, Huijuan; Kim, Joung Joo; Liu, Siyang; Ko, Kyeong Hee; Huang, Shujia; Hwang, In Sung; Kang, Mi Na; Gong, Desheng; Park, Kang Bae; Choi, Eun Ji; Park, Jung Hyun; Jeong, Yeon Woo; Moon, Changjong; Hyun, Sang-Hwan; Kim, Nam Hyung; Jeung, Eui-Bae; Yang, Huanming; Hwang, Woo Suk; Gao, Fei

    2016-01-01

    Somatic cell nuclear transfer (SCNT) provides an excellent model for studying epigenomic reprogramming during mammalian development. We mapped the whole genome and whole methylome for potential anomalies of mutations or epimutations in SCNT-generated dogs with XY chromosomal sex but complete gonadal dysgenesis, which is classified as 78, XY disorder of sex development (DSD). Whole genome sequencing revealed no potential genomic variations that could explain the pathogenesis of DSD. However, extensive but stochastic anomalies of genome-wide DNA methylation were discovered in these SCNT DSD dogs. Persistent abnormal hypermethylation of the SRY gene was observed together with its down-regulated mRNA and protein expression. Failure of SRY expression due to hypermethylation was further correlated with silencing of a serial of testis determining genes, including SOX9, SF1, SOX8, AMH and DMRT1 in an early embryonic development stage at E34 in the XYDSD gonad, and high activation of the female specific genes, including FOXL2, RSPO1, CYP19A1, WNT4, ERα and ERβ, after one postnatal year in the ovotestis. Our results demonstrate that incomplete demethylation on the SRY gene is the driving cause of XYDSD in these XY DSD dogs, indicating a central role of epigenetic regulation in sex determination. PMID:27501986

  8. Enhydrina schistosa (Elapidae: Hydrophiinae) the most dangerous sea snake in Sri Lanka: three case studies of severe envenoming.

    PubMed

    Kularatne, S A M; Hettiarachchi, R; Dalpathadu, J; Mendis, A S V; Appuhamy, P D S A N; Zoysa, H D J; Maduwage, K; Weerasinghe, V S; de Silva, A

    2014-01-01

    Sea snakes are highly venomous and inhabit tropical waters of the Indian and Pacific Oceans. Enhydrina schistosa is a common species of sea snake that lives in the coastal waters, lagoons, river mouths and estuaries from the Persian Gulf through Sri Lanka and to Southeast Asia. It is considered one of the most aggressive sea snakes in Sri Lanka where fishermen and people wading are at high risk. However, sea snake bites are rarely reported. In this report, we describe three cases where E. schistosa was the offending species. These three patients presented to two hospitals on the west coast of Sri Lanka within the course of 14 months from November 2011 with different degrees of severity of envenoming. The first patient was a 26-year-old fisherman who developed severe myalgia with very high creatine kinase (CK) levels lasting longer than 7 days. The second patient was a 32-year-old fisherman who developed gross myoglobinuria, high CK levels and hyperkalaemia. Both patients recovered and their electromyographic recordings showed myopathic features. The nerve conduction and neuromuscular transmission studies were normal in both patients suggesting primary myotoxic envenoming. The third patient was a 41-year-old man who trod on a sea snake in a river mouth and developed severe myalgia seven hours later. He had severe rhabdomyolysis and died three days later due to cardiovascular collapse. In conclusion, we confirm that E. schistosa is a deadly sea snake and its bite causes severe rhabdomyolysis. PMID:24239658

  9. Impact of economic labour migration: a qualitative exploration of left-behind family member perspectives in Sri Lanka.

    PubMed

    Siriwardhana, Chesmal; Wickramage, Kolitha; Jayaweera, Kaushalya; Adikari, Anushka; Weerawarna, Sulochana; Van Bortel, Tine; Siribaddana, Sisira; Sumathipala, Athula

    2015-06-01

    Sri Lanka is a major labour sending country in Asia, with a high proportion of female labour migrants employed as domestic housemaids in the Middle East with increasing remittances. Despite such financial gains for families and national economy, health and social effects on the left-behind families have had limited exploration. This qualitative study was carried out across five districts with high labour migration rates in Sri Lanka. Twenty in-depth interviews were conducted with participants recruited through purposive sampling. Data was analysed using content and thematic analysis and emerging themes were mapped. Pre-migration socio-economic situation, economic difficulties and higher earning possibilities abroad were considered to be the major push and pull factors for labour migration. Post-migration periods were shown to be of mixed benefit to left-behind families and children suffer the negative effects of parental absence. The absence of support mechanisms for dealing with adverse events such as serious injury, death, abuse or imprisonment were cited as major concerns. Post-migration periods affect the health, well-being and family structures of left-behind families. Promoting economic prosperity while ensuring health and social protection is a formidable policy challenge for 'labour sending' countries such as Sri Lanka. PMID:24242226

  10. Stochastic anomaly of methylome but persistent SRY hypermethylation in disorder of sex development in canine somatic cell nuclear transfer.

    PubMed

    Jeong, Young-Hee; Lu, Hanlin; Park, Chi-Hun; Li, Meiyan; Luo, Huijuan; Kim, Joung Joo; Liu, Siyang; Ko, Kyeong Hee; Huang, Shujia; Hwang, In Sung; Kang, Mi Na; Gong, Desheng; Park, Kang Bae; Choi, Eun Ji; Park, Jung Hyun; Jeong, Yeon Woo; Moon, Changjong; Hyun, Sang-Hwan; Kim, Nam Hyung; Jeung, Eui-Bae; Yang, Huanming; Hwang, Woo Suk; Gao, Fei

    2016-01-01

    Somatic cell nuclear transfer (SCNT) provides an excellent model for studying epigenomic reprogramming during mammalian development. We mapped the whole genome and whole methylome for potential anomalies of mutations or epimutations in SCNT-generated dogs with XY chromosomal sex but complete gonadal dysgenesis, which is classified as 78, XY disorder of sex development (DSD). Whole genome sequencing revealed no potential genomic variations that could explain the pathogenesis of DSD. However, extensive but stochastic anomalies of genome-wide DNA methylation were discovered in these SCNT DSD dogs. Persistent abnormal hypermethylation of the SRY gene was observed together with its down-regulated mRNA and protein expression. Failure of SRY expression due to hypermethylation was further correlated with silencing of a serial of testis determining genes, including SOX9, SF1, SOX8, AMH and DMRT1 in an early embryonic development stage at E34 in the XY(DSD) gonad, and high activation of the female specific genes, including FOXL2, RSPO1, CYP19A1, WNT4, ERα and ERβ, after one postnatal year in the ovotestis. Our results demonstrate that incomplete demethylation on the SRY gene is the driving cause of XY(DSD) in these XY DSD dogs, indicating a central role of epigenetic regulation in sex determination. PMID:27501986

  11. Comparative Analysis of Lipid Content and Fatty Acid Composition of Commercially Important Fish and Shellfish from Sri Lanka and Japan.

    PubMed

    Devadason, Chandravathany; Jayasinghe, Chamila; Sivakanesan, Ramiah; Senarath, Samanthika; Beppu, Fumiaki; Gotoh, Naohiro

    2016-01-01

    Sri Lanka is surrounded by the Indian Ocean, allowing plenty of fishes to be caught. Moreover, these fishes represent one of the undocumented fish resources in the world and their detailed lipid profiles have not been previously examined. In this study, the lipid content and fatty acid composition of 50 commercially important fishes from the Indian Ocean (Sri Lanka) and the Pacific Ocean (Japan) were compared. The total lipid content and fatty acid composition, including eicosapentaenoic acid (C20:5n-3, EPA) and docosahexaenoic acid (C22:6n-3, DHA), differed significantly among species. Fish from the Pacific Ocean had higher proportions of fatty acids, including EPA and DHA. Herrings and mackerels from both oceanic areas demonstrated high levels of EPA and DHA, and n-3/n-6 ratio. Brackish and freshwater fishes from both groups showed low levels of PUFAs. Fish from the Indian Ocean were high in n-6 fatty acids. Monounsaturated fatty acid levels were high in omnivorous fish from the Pacific Ocean, and saturated fatty acid levels were high in fish from the Indian Ocean. The results of this study will be of value in determining the dietary usefulness of fish caught in Sri Lanka. PMID:27373421

  12. Is Hiding Foot and Mouth Disease Sensitive Behavior for Farmers? A Survey Study in Sri Lanka

    PubMed Central

    Gunarathne, Anoma; Kubota, Satoko; Kumarawadu, Pradeep; Karunagoda, Kamal; Kon, Hiroichi

    2016-01-01

    Foot and mouth disease (FMD) has a long history in Sri Lanka and was found to be endemic in various parts of the country and constitutes a constant threat to farmers. In Sri Lanka, currently there is no regular, nationwide vaccination programme devised to control FMD. Therefore, improving farmers’ knowledge regarding distinguishing FMD from other diseases and ensuring prompt reporting of any suspicion of FMD as well as restricting movement of animals are critical activities for an effective FMD response effort. Therefore, the main purpose of this study was to clarify the relationship between farmers’ knowledge levels and their behaviors to establish a strategy to control FMD. In our study, item count technique was applied to estimate the number of farmers that under-report and sell FMD-infected animals, although to do so is prohibited by law. The following findings were observed: about 63% of farmers have very poor knowledge of routes of FMD transmission; ‘under-reporting’ was found to be a sensitive behavior and nearly 23% of the farmers were reluctant to report FMD-infected animals; and ‘selling FMD-infected animals’ is a sensitive behavior among high-level knowledge group while it is a non-sensitive behavior among the low-level knowledge group. If farmers would understand the importance of prompt reporting, they may report any suspected cases of FMD to veterinary officials. However, even if farmers report honestly, they do not want to cull FMD-infected animals. Thus, education programs should be conducted not only on FMD introduction and transmission, but also its impact. Furthermore, consumers may criticize the farmers for culling their infected animals. Hence, not only farmers, but also consumers need to be educated on the economic impact of FMD and the importance of controlling an outbreak. If farmers have a high knowledge of FMD transmission, they consider selling FMD-infected animals as a sensitive behavior. Therefore, severe punishment should

  13. Laboratory studies of dune sand for the use of construction industry in Sri Lanka

    NASA Astrophysics Data System (ADS)

    de Silva Jayawardena, Upali; Wijesuriya, Roshan; Abayaweera, Gayan; Viduranga, Tharaka

    2015-04-01

    With the increase of the annual sand demand for the construction industry the excessive excavation of river sand is becoming a serious environmental problem in Sri Lanka. Therefore, it is necessary to explore the possibility for an alternative to stop or at least to minimize river sand mining activities. Dune sand is one of the available alternative materials to be considered instead of river sand in the country. Large quantities of sand dunes occur mainly along the NW and SE coastal belt which belong to very low rainfall Dry Zone coasts. The height of dune deposits, vary from 1m to about 30 meters above sea level. The objective of this paper is to indicate some studies and facts on the dune sand deposits of Sri Lanka. Laboratory studies were carried out for visual observations and physical properties at the initial stage and then a number of tests were carried out according to ASTM standards to obtain the compressive strength of concrete cylinders and mortar cubes mixing dune sand and river sand in different percentages keeping a constant water cement ratio. Next the water cement ratio was changed for constant dune sand and river sand proportion. Microscopic analysis shows that the dune sand consist of 95 % of quartz and 5 % of garnet, feldspar, illmenite and other heavy minerals with clay, fine dust, fine shell fragments and organic matters. Grains are sub-rounded to angular and tabular shapes. The grain sizes vary from fine to medium size of sand with silt. The degree of sorting and particle size observed with dune sands are more suited with the requirement of fine aggregates in the construction industry. The test result indicates that dune sand could be effectively used in construction work without sieving and it is ideal for wall plastering due to its'-uniformity. It could also be effectively used in concrete and in mortars mixing with river sand. The best mixing ratio is 75% dune sand and 25% river sand as the fine aggregate of concrete. For mortar the mixing

  14. Bridgman growth of large SrI2:Eu2+ single crystals: A high-performance scintillator for radiation detection applications

    NASA Astrophysics Data System (ADS)

    Boatner, L. A.; Ramey, J. O.; Kolopus, J. A.; Hawrami, R.; Higgins, W. M.; van Loef, E.; Glodo, J.; Shah, K. S.; Rowe, Emmanuel; Bhattacharya, Pijush; Tupitsyn, Eugene; Groza, Michael; Burger, Arnold; Cherepy, N. J.; Payne, S. A.

    2013-09-01

    Single-crystal strontium iodide (SrI2) doped with relatively high levels (e.g., 3-6%) of Eu2+ exhibits characteristics that make this material superior, in a number of respects, to other scintillators that are currently used for radiation detection. Specifically, SrI2:Eu2+ has a light yield that is significantly higher than LaBr3:Ce3+—a currently employed commercial high-performance scintillator. Additionally, SrI2:Eu2+ is characterized by an energy resolution as high as 2.6% at the 137Cs gamma-ray energy of 662 keV, and there is no radioactive component in SrI2:Eu2+—unlike LaBr3:Ce3+ that contains 138La. The Ce3+-doped LaBr3 decay time is, however, faster (30 ns) than the 1.2 μs decay time of SrI2:Eu2+. Due to the relatively low melting point of strontium iodide (˜515 °C), crystal growth can be carried out in quartz crucibles by the vertical Bridgman technique. Materials-processing and crystal-growth techniques that are specific to the Bridgman growth of europium-doped strontium iodide scintillators are described here. These techniques include the use of a porous quartz frit to physically filter the molten salt from a quartz antechamber into the Bridgman growth crucible and the use of a "bent" or "bulb" grain selector design to suppress multiple grain growth. Single crystals of SrI2:Eu2+ scintillators with good optical quality and scintillation characteristics have been grown in sizes up to 5.0 cm in diameter by applying these techniques. Other aspects of the SrI2:Eu2+ crystal-growth methods and of the still unresolved crystal-growth issues are described here.

  15. Hermansky-Pudlak syndrome type 4 in a patient from Sri Lanka with pulmonary fibrosis.

    PubMed

    Bachli, Esther B; Brack, Thomas; Eppler, Elisabeth; Stallmach, Thomas; Trüeb, Ralph M; Huizing, Marjan; Gahl, William A

    2004-06-01

    Hermansky-Pudlak syndrome (HPS) is a rare autosomal recessive disorder characterized by oculocutaneous albinism and a platelet storage pool deficiency. Some patients also develop fatal pulmonary fibrosis and some have granulomatous colitis. Six human genes HPS1, ADB3A, HPS3, HPS4, HPS5, and HPS6 have been identified as cause of the six known subtypes of HPS. While there exist nearly 500 Puerto Rican and non-Puerto Rican HPS-1 patients, very few HPS-4 patients have been reported, and most of these have not been described in detail. We now delineate the clinical characteristics of an HPS-4 patient homozygous for a novel HPS-4 mutation, P685delC. The patient, the first individual with HPS reported from Sri Lanka, had severe pulmonary fibrosis, typical of HPS-1 disease, without granulomatous colitis. We conclude that pulmonary fibrosis occurs as part of HPS-4 and that HPS should be considered in all ethnic groups. PMID:15108212

  16. Geologic impacts of the 2004 Indian ocean tsunami on Indonesia, Sri Lanka, and the Maldives

    USGS Publications Warehouse

    Richmond, B.M.; Jaffe, B.E.; Gelfenbaum, G.; Morton, R.A.

    2006-01-01

    The December 26, 2004 Indian Ocean tsunami was generated by a large submarine earthquake (magnitude ???9.1) with an epicenter located under the seafloor in the eastern Indian Ocean near northern Sumatra, Indonesia. The resulting tsunami was measured globally and had significant geologic impacts throughout the Indian Ocean basin. Observations of tsunami impacts, such as morphologic change, sedimentary deposits, and water-level measurements, are used to reconstruct tsunamogenic processes. Data from Sumatra, Sri Lanka, and the Maldives provide a synoptic view of tsunami characteristics from a wide range of coastal environments both near- and far-field from the tsunami origin. Impacts to the coast as a result of the tsunami varied depending upon the height of the wave at impact, orientation of the coast with regard to direction of wave approach, and local topography, bathymetry, geology, and vegetation cover. Tsunami deposits were observed in all the countries visited and can be generally characterized as relatively thin sheets (<80 cm), mostly of sand. ?? 2006 Gebru??der Borntraeger.

  17. Implementation of genomic medicine in Sri Lanka: Initial experience and challenges.

    PubMed

    Sirisena, Nirmala D; Neththikumara, Nilaksha; Wetthasinghe, Kalum; Dissanayake, Vajira H W

    2016-06-01

    The recent advances in next generation sequencing technologies have made it possible to implement genomic medicine in developing countries such as Sri Lanka where capacity for utilization is limited. This paper aims to describe our initial experience and challenges faced in integrating genomic medicine into routine clinical practice. Using the Illumina MiSeq Next generation sequencing (NGS) platform and an in-house developed bioinformatics pipeline/workflow, we successfully implemented clinical exome sequencing for rare disorders, complex disorders with unusual coexisting phenotypes, and multigene cancer panel testing for inherited cancer syndromes. The advantages of implementing these tests, the challenges for bioinformatics analysis and reporting, the ethical, legal, and social implications of moving from genetic to genomic counseling, and special policy issues related to implementing these tests are further discussed. The implementation of genomic medicine into our routine clinical practice has facilitated improved care for our patients, attesting to the ability of resource limited countries to improve care using advanced genomic technology. PMID:27354939

  18. Predictors of violence against children in Tamil families in northern Sri Lanka.

    PubMed

    Sriskandarajah, Vathsalan; Neuner, Frank; Catani, Claudia

    2015-12-01

    Children living in post-conflict settings are not only at high risk of developing war-related psychopathology but also of experiencing maltreatment within their families. However, little is known about the mechanisms of the relationship between war and family violence. In order to investigate the variables associated with the experience and perpetration of child maltreatment, we conducted a two-generational study with Tamil families in the North of Sri Lanka, a region affected by war and Tsunami. We interviewed children and the corresponding family dyads and triads with 359 children, 122 mothers, and 88 fathers on the basis of standardized questionnaires to assess their exposure to adverse life experiences and mental health symptoms. Using multivariate regression analyses, we found that the strongest predictors for children's report of victimization were children's exposure to mass trauma and child psychopathology. Mothers' experiences of mass trauma, family violence and partner violence were each significantly related to mother-reported maternal perpetration as well as child-reported victimization. Likewise, all types of traumatic events reported by fathers were significantly related to child-reported victimization and father-reported perpetration. Fathers' alcohol use was the strongest predictor of father-reported paternal perpetration. These findings provide further support for the transmission of mass trauma into family violence, and emphasize the role of child psychopathology as well as alcohol consumption in this relationship. PMID:26521032

  19. Effect of Hydroxypropylation on Functional Properties of Different Cultivars of Sweet Potato Starch in Sri Lanka.

    PubMed

    Senanayake, Suraji; Gunaratne, Anil; Ranaweera, K K D S; Bamunuarachchi, Arthur

    2014-01-01

    Starches obtained from different cultivars of sweet potatoes commonly consumed in Sri Lanka, were chemically modified with hydroxypropyl substitution, to analyze the changes in the physicochemical properties. Significant changes (P < 0.05) in the crude digestibility level, thermal properties, and the water separation (syneresis) of starch gels (7.0% db) during cold and frozen storage were observed due to the modification. Hydroxypropylation increased the gel stability, water solubility, digestibility, and storage stability of the native starches in the cold storage to a significant level. Lowered gelatinization and retrogradation enthalpies as well as gelatinization temperature were observed for derivatized starches compared to the native starch. Low levels of pasting stability with increased levels of breakdown and reduced cold paste viscosity were observed in the hydroxypropylated starch samples except for the Malaysian cultivar (S5). Chemically modified starch gels stored under cold storage did not show a syneresis for two weeks in the cycle and the frozen storage showed much improved stability in the starch gels within the four-week cycle. Chemical modification of sweet potato starch with hydroxyl propyl substitution can enhance the functional characteristics of the native starch which will improve its potential application in the food industry. PMID:26904619

  20. Beyond individual war trauma: domestic violence against children in Afghanistan and Sri Lanka.

    PubMed

    Catani, Claudia; Schauer, Elisabeth; Neuner, Frank

    2008-04-01

    To date, research on the psychosocial consequences of mass trauma resulting from war and organized violence on children has primarily focused on the individual as the unit of treatment and analysis with particular focus on mental disorders caused by traumatic stress. This body of research has stimulated the development of promising individual-level treatment approaches for addressing psychological trauma. In contrast, there is virtually no literature addressing the effects of mass trauma on the family and community systems. Research conducted in Sri Lanka and Afghanistan, two long-standing war-torn societies, found that in addition to multiple exposure to war or disaster-related traumatic events children also indicated high levels of exposure to family violence. These findings point to the need for conjoint family- and community-based programs of prevention and intervention that are specifically tailored for the context of the affected society. In particular, programs should take issues such as poverty, child labor, and parental alcohol use into account in assessing and treating children in the aftermath of mass trauma. PMID:18412824