Science.gov

Sample records for study objective the aim

  1. The Aims and Objectives of the Monitoring the Future Study and Progress toward Fulfilling Them as of 2006. Monitoring the Future Occasional Paper Paper 65

    ERIC Educational Resources Information Center

    Johnston, Lloyd D.; O'Malley, Patrick M.; Schulenberg, John E.; Bachman, Jerald G.

    2006-01-01

    Monitoring the Future is an ongoing program of research intended to assess the changing lifestyles, values, and preferences of American youth. This publication, from the occasional paper series, describes a study that monitors drug use and potential explanatory factors among American secondary school students, college students, and young adults.…

  2. The EvA study: aims and strategy.

    PubMed

    Ziegler-Heitbrock, Loems; Frankenberger, Marion; Heimbeck, Irene; Burggraf, Dorothe; Wjst, Matthias; Häussinger, Karl; Brightling, Chris; Gupta, Sumit; Parr, David; Subramanian, Deepak; Singh, Dave; Kolsum, Umme; Boschetto, Piera; Potena, Alfredo; Gorecka, Dorota; Nowinski, Adam; Barta, Imre; Döme, Balazs; Strausz, Janos; Greulich, Timm; Vogelmeier, Claus; Bals, Robert; Hohlfeld, Jens M; Welte, Tobias; Venge, Per; Gut, Ivo; Boland, Anne; Olaso, Robert; Hager, Jörg; Hiemstra, Pieter; Rabe, Klaus F; Unmüssig, Martina; Müller-Quernheim, Joachim; Prasse, Antje

    2012-10-01

    The EvA study is a European Union-funded project under the Seventh Framework Programme (FP7), which aims at defining new markers for chronic obstructive pulmonary disease (COPD) and its subtypes. The acronym is derived from emphysema versus airway disease, indicating that the project targets these two main phenotypes of the disease. The EvA study is based on the concept that emphysema and airway disease are governed by different pathophysiological processes, are driven by different genes and have differential gene expression in the lung. To define these genes, patients and non-COPD controls are recruited for clinical examination, lung function analysis and computed tomography (CT) of the lung. CT scans are used to define the phenotypes based on lung density and airway wall thickness. This is followed by bronchoscopy in order to obtain samples from the airways and the alveoli. These tissue samples, along with blood samples, are then subjected to genome-wide expression and association analysis and markers linked to the phenotypes are identified. The population of the EvA study is different from other COPD study populations, since patients with current oral glucocorticoids, antibiotics and exacerbations or current smokers are excluded, such that the signals detected in the molecular analysis are due to the distinct inflammatory process of emphysema and airway disease in COPD. PMID:22441733

  3. Religious Studies, Religious Education and the Aims of Education

    ERIC Educational Resources Information Center

    Barnes, L. Philip

    2015-01-01

    This article interacts with a recent article by Denise Cush and Catherine Robinson in which they call for a new dialogue between religious studies in universities and religious education, and identify a number of developments in religious studies that have implications for the practice of religious education in schools. Cush and Robinson are…

  4. Taking Triple Aim at the Triple Aim.

    PubMed

    Bryan, Stirling; Donaldson, Cam

    2016-01-01

    Since its introduction to the USA, the Triple Aim is now being adopted in the healthcare systems of other advanced economies. Verma and Bhatia (2016) (V&B) argue that provincial governments in Canada now need to step up to the plate and lead on the implementation of a Triple Aim reform program here. Their proposals are wide ranging and ambitious, looking for governments to act as the "integrators" within the healthcare system, and lead the reforms. Our view is that, as a vision and set of goals for the healthcare system, the Triple Aim is all well and good, but as a pathway for system reform, as articulated by V&B, it misses the mark in at least three important respects. First, the emphasis on improvement driven by performance measurement and pay-for-performance is troubling and flies in the face of emerging evidence. Second, we know that scarcity can be recognized and managed, even in politically complex systems, and so we urge the Triple Aim proponents to embrace more fully notions of resource stewardship. Third, if we want to take seriously "population health" goals, we need to think very differently and consider broader health determinants; Triple Aim innovation targeted at healthcare systems will not deliver the goals. PMID:27009583

  5. The FBI Takes Aim at AIM

    ERIC Educational Resources Information Center

    Kanter, Elliot

    1977-01-01

    The events and revelations before and since the arrest of Paul Skyhorse and Richard Mohawk (two American Indian Movement organizers charged with the 1974 murder of a taxi driver at AIM Camp 13) lead to the inevitable conclusion that these men are victims of a frame-up. (Author/JC)

  6. Measurement and Analysis of Olfactory Responses with the Aim of Establishing an Objective Diagnostic Method for Central Olfactory Disorders

    NASA Astrophysics Data System (ADS)

    Uno, Tominori; Wang, Li-Qun; Miwakeichi, Fumikazu; Tonoike, Mitsuo; Kaneda, Teruo

    In order to establish a new diagnostic method for central olfactory disorders and to identify objective indicators, we measured and analyzed brain activities in the parahippocampal gyrus and uncus, region of responsibility for central olfactory disorders. The relationship between olfactory stimulation and brain response at region of responsibility can be examined in terms of fitted responses (FR). FR in these regions may be individual indicators of changes in brain olfactory responses. In the present study, in order to non-invasively and objectively measure olfactory responses, an odor oddball task was conducted on four healthy volunteers using functional magnetic resonance imaging (fMRI) and a odorant stimulator with blast-method. The results showed favorable FR and activation in the parahippocampal gyrus or uncus in all subjects. In some subjects, both the parahippocampal gyrus and uncus were activated. Furthermore, activation was also confirmed in the cingulate gyrus, middle frontal gyrus, precentral gyrus, postcentral gyrus, superior temporal gyrus and insula. The hippocampus and uncus are known to be involved in the olfactory disorders associated with early-stage Alzheimer's disease and other olfactory disorders. In the future, it will be necessary to further develop the present measurement and analysis method to clarify the relationship between central olfactory disorders and brain activities and establish objective indicators that are useful for diagnosis.

  7. Parents' Views Regarding the Values Aimed to be Taught in Social Studies Lessons

    ERIC Educational Resources Information Center

    Tay, Bayram; Yildirim, Kasim

    2009-01-01

    This study aimed at learning parents' ideas about the values aimed to be taught in Social Studies lessons in the 4th and 5th grades of the primary education and about values education. Study data were collected by administering "the Values Education I" and "Values Education II" questionnaire forms developed by the researchers. The views of 378 and…

  8. Aiming for the Green

    ERIC Educational Resources Information Center

    Kennedy, Mike

    2007-01-01

    Times change, and pollution continues to plague cities, energy prices escalate and average temperatures creep higher, the argument that society cannot afford to squander its limited resources has been embraced by more than just environmental activists. More and more education administrators and architects are among those pushing schools and…

  9. Interpretive Research Aiming at Theory Building: Adopting and Adapting the Case Study Design

    ERIC Educational Resources Information Center

    Diaz Andrade, Antonio

    2009-01-01

    Although the advantages of case study design are widely recognised, its original positivist underlying assumptions may mislead interpretive researchers aiming at theory building. The paper discusses the limitations of the case study design for theory building and explains how grounded theory systemic process adds to the case study design. The…

  10. Cross-cultural exchange: How students can frustrate the aims of study abroad programmes

    NASA Astrophysics Data System (ADS)

    Barnes, Leslie R.

    1982-09-01

    Readily accepting that study abroad programmes may have as many differing forms and aims as there are participating institutions, and that by no means all programmes include academic content in their goals, I would nevertheless maintain: 1. that a sociological perspective is as necessary as the hitherto predominantly psychological approach in obtaining a balanced assessment of study abroad programmes;

  11. Systematic Review of the Methodological Quality of Studies Aimed at Creating Gestational Weight Gain Charts.

    PubMed

    Ohadike, Corah O; Cheikh-Ismail, Leila; Ohuma, Eric O; Giuliani, Francesca; Bishop, Deborah; Kac, Gilberto; Puglia, Fabien; Maia-Schlüssel, Michael; Kennedy, Stephen H; Villar, José; Hirst, Jane E

    2016-03-01

    A range of adverse outcomes is associated with insufficient and excessive maternal weight gain in pregnancy, but there is no consensus regarding what constitutes optimal gestational weight gain (GWG). Differences in the methodological quality of GWG studies may explain the varying chart recommendations. The goal of this systematic review was to evaluate the methodological quality of studies that aimed to create GWG charts by scoring them against a set of predefined, independently agreed-upon criteria. These criteria were divided into 3 domains: study design (12 criteria), statistical methods (7 criteria), and reporting methods (4 criteria). The criteria were broken down further into items, and studies were assigned a quality score (QS) based on these criteria. For each item, studies were scored as either high (score = 0) or low (score = 1) risk of bias; a high QS correlated with a low risk of bias. The maximum possible QS was 34. The systematic search identified 12 eligible studies involving 2,268,556 women from 9 countries; their QSs ranged from 9 (26%) to 29 (85%) (median, 18; 53%). The most common sources for bias were found in study designs (i.e., not prospective); assessments of prepregnancy weight and gestational age; descriptions of weighing protocols; sample size calculations; and the multiple measurements taken at each visit. There is wide variation in the methodological quality of GWG studies constructing charts. High-quality studies are needed to guide future clinical recommendations. We recommend the following main requirements for future studies: prospective design, reliable evaluation of prepregnancy weight and gestational age, detailed description of measurement procedures and protocols, description of sample-size calculation, and the creation of smooth centile charts or z scores. PMID:26980814

  12. The Asteroid Impact Mission (AIM)

    NASA Astrophysics Data System (ADS)

    Küppers, M.; Carnelli, I.; Galvez, A.; Mellab, K.; Michel, P.; AIM Team

    2015-10-01

    The Asteroid Impact Mission (AIM) is ESA's contribution to an international cooperation targeting the demonstration of deflection of a hazardous nearearth asteroid as well as the first in-depth investigation of a binary asteroid. After launch in 2020, AIM will rendezvous the binary near-Earth asteroid (65803) Didymos in 2022 and observe the system before, during, and after the impact of NASA's Double Asteroid Redirection Test (DART) spacecraft. The AIM mission will test new technologies like optical telecommunications by laser and Cubesats with nano-payloads and will perform scientific measurements at the asteroid system.

  13. Animation of the AIM Spacecraft

    NASA Video Gallery

    AIM will make simultaneous measurements of the main ingredients needed to form these clouds and will unravel the role of natural factors, such as the solar cycle and meteorology, from the possible ...

  14. The Aims of College Teaching.

    ERIC Educational Resources Information Center

    Eble, Kenneth E.

    The aims of college teaching are discussed, and a comparison of higher education in 1960 and two decades later is provided. After considering the development of a teaching style and the importance of the teacher's character, the joyful and spontaneous side of teaching are considered. The nature of teaching (i.e., art, science, or craft) is also…

  15. Construction of a digital and physical mouse model aimed at the study of electrical shock

    NASA Astrophysics Data System (ADS)

    Nguyen, Thu T. A.; Shupp, Jeffrey W.; Moffatt, Lauren T.; Ramella-Roman, Jessica C.

    2014-03-01

    Optical methods have been used to investigate electrical injury on animal models such as live mice, rats, and rabbits. Here we introduce a completely digital phantom of a mouse, with the aim of investigating electrical injury through spectroscopic imaging techniques. The basis of our phantom is a three-dimensional digital mouse reconstructed from co-registered computed tomographic images and cryosection by a different group. Image processing algorithms were applied to make the model suitable to Finite Element Analysis of thermal and electrical transport. Our digital model is capable of simulating temperature, voltage, current changes along the animal body during and after electrical shocks.

  16. New Seismic Hazard study in Spain Aimed at the revision of the Spanish Building Code

    NASA Astrophysics Data System (ADS)

    Rivas-Medina, A.; Benito, B.; Cabañas, L.; Martínez-Solares, J. M.; Ruíz, S.; Gaspar-Escribano, J. M.; Carreño, E.; Crespo, M.; García-Mayordomo, J.

    2013-05-01

    In this paper we present a global overview of the recent study carried out in Spain for the new hazard map, which final goal is the revision of the Building Code in our country (NCSE-02). The study was carried our for a working group joining experts from The Instituto Geografico Nacional (IGN) and the Technical University of Madrid (UPM) , being the different phases of the work supervised by an expert Committee integrated by national experts from public institutions involved in subject of seismic hazard. The PSHA method (Probabilistic Seismic Hazard Assessment) has been followed, quantifying the epistemic uncertainties through a logic tree and the aleatory ones linked to variability of parameters by means of probability density functions and Monte Carlo simulations. In a first phase, the inputs have been prepared, which essentially are: 1) a project catalogue update and homogenization at Mw 2) proposal of zoning models and source characterization 3) calibration of Ground Motion Prediction Equations (GMPE's) with actual data and development of a local model with data collected in Spain for Mw < 5.5. In a second phase, a sensitivity analysis of the different input options on hazard results has been carried out in order to have criteria for defining the branches of the logic tree and their weights. Finally, the hazard estimation was done with the logic tree shown in figure 1, including nodes for quantifying uncertainties corresponding to: 1) method for estimation of hazard (zoning and zoneless); 2) zoning models, 3) GMPE combinations used and 4) regression method for estimation of source parameters. In addition, the aleatory uncertainties corresponding to the magnitude of the events, recurrence parameters and maximum magnitude for each zone have been also considered including probability density functions and Monte Carlo simulations The main conclusions of the study are presented here, together with the obtained results in terms of PGA and other spectral accelerations

  17. A Comparative Investigation of the Previous and New Secondary History Curriculum: The Issues of the Definition of the Aims and Objectives and the Selection of Curriculum Content

    ERIC Educational Resources Information Center

    Dinc, Erkan

    2011-01-01

    Discussions on history teaching in Turkey indicate that the previous versions of the history curriculum and the pedagogy of history in the country bear many problems and deficiencies. The problems of Turkish history curriculum mainly arise from the perspectives it takes and the selection of its content. Since 2003, there have been extensive…

  18. The use of HIV-1 integration site analysis information in clinical studies aiming at HIV cure.

    PubMed

    Kiselinova, Maja; De Spiegelaere, Ward; Vandekerckhove, Linos

    2016-01-01

    The mechanisms for the establishment and the persistence of the latent HIV-1 reservoir remain to be completely defined. HIV-1 infection is characterised by the integration of the reverse transcribed proviral DNA into the host's genome. This integrated proviral DNA can remain replication silent, but a small part of it is fully competent to restart viral replication when treatment is interrupted. Hence, this replication-competent provirus is the cause of viral rebound and is called the viral reservoir. The exact site of proviral integration within the host's cellular chromosome may affect the transcriptional activity of HIV. Thanks to recent technological advances, HIV-1 integration site analysis has been used to assess HIV-1 reservoirs in HIV-infected individuals. Analysis of HIV-1 integration sites in infected individuals undergoing suppressive ART led to identification of expanded clonal cell populations, indicating that clonal proliferation of the proviral reservoir may contribute to the long-term persistence of viral reservoirs. Here we describe the findings of several clinical studies, where a comprehensive HIV-1 integration site analysis was performed. PMID:27482458

  19. Grid-based precision aim system and method for disrupting suspect objects

    SciTech Connect

    Gladwell, Thomas Scott; Garretson, Justin; Hobart, Clinton G.; Monda, Mark J.

    2014-06-10

    A system and method for disrupting at least one component of a suspect object is provided. The system has a source for passing radiation through the suspect object, a grid board positionable adjacent the suspect object (the grid board having a plurality of grid areas, the radiation from the source passing through the grid board), a screen for receiving the radiation passing through the suspect object and generating at least one image, a weapon for deploying a discharge, and a targeting unit for displaying the image of the suspect object and aiming the weapon according to a disruption point on the displayed image and deploying the discharge into the suspect object to disable the suspect object.

  20. A 3-Month Jump-Landing Training Program: A Feasibility Study Using the RE-AIM Framework

    PubMed Central

    Aerts, Inne; Cumps, Elke; Verhagen, Evert; Mathieu, Niels; Van Schuerbeeck, Sander; Meeusen, Romain

    2013-01-01

    Context: Evaluating the translatability and feasibility of an intervention program has become as important as determining the effectiveness of the intervention. Objective: To evaluate the applicability of a 3-month jump-landing training program in basketball players, using the RE-AIM (reach, effectiveness, adoption, implementation, and maintenance) framework. Design: Randomized controlled trial. Setting: National and regional basketball teams. Patients or Other Participants: Twenty-four teams of the second highest national division and regional basketball divisions in Flanders, Belgium, were randomly assigned (1:1) to a control group and intervention group. A total of 243 athletes (control group = 129, intervention group = 114), ages 15 to 41 years, volunteered. Intervention(s): All exercises in the intervention program followed a progressive development, emphasizing lower extremity alignment during jump-landing activities. Main Outcome Measure(s): The results of the process evaluation of the intervention program were based on the 5 dimensions of the RE-AIM framework. The injury incidence density, hazard ratios, and 95% confidence intervals were determined. Results: The participation rate of the total sample was 100% (reach). The hazard ratio was different between the intervention group and the control group (0.40 [95% confidence interval = 0.16, 0.99]; effectiveness). Of the 12 teams in the intervention group, 8 teams (66.7%) agreed to participate in the study (adoption). Eight of the participating coaches (66.7%) felt positively about the intervention program and stated that they had implemented the training sessions of the program as intended (implementation). All coaches except 1 (87.5%) intended to continue the intervention program the next season (maintenance). Conclusions: Compliance of the coaches in this coach-supervised jump-landing training program was high. In addition, the program was effective in preventing lower extremity injuries. PMID:23675788

  1. Study Protocol - Accurate assessment of kidney function in Indigenous Australians: aims and methods of the eGFR Study

    PubMed Central

    2010-01-01

    Background There is an overwhelming burden of cardiovascular disease, type 2 diabetes and chronic kidney disease among Indigenous Australians. In this high risk population, it is vital that we are able to measure accurately kidney function. Glomerular filtration rate is the best overall marker of kidney function. However, differences in body build and body composition between Indigenous and non-Indigenous Australians suggest that creatinine-based estimates of glomerular filtration rate derived for European populations may not be appropriate for Indigenous Australians. The burden of kidney disease is borne disproportionately by Indigenous Australians in central and northern Australia, and there is significant heterogeneity in body build and composition within and amongst these groups. This heterogeneity might differentially affect the accuracy of estimation of glomerular filtration rate between different Indigenous groups. By assessing kidney function in Indigenous Australians from Northern Queensland, Northern Territory and Western Australia, we aim to determine a validated and practical measure of glomerular filtration rate suitable for use in all Indigenous Australians. Methods/Design A cross-sectional study of Indigenous Australian adults (target n = 600, 50% male) across 4 sites: Top End, Northern Territory; Central Australia; Far North Queensland and Western Australia. The reference measure of glomerular filtration rate was the plasma disappearance rate of iohexol over 4 hours. We will compare the accuracy of the following glomerular filtration rate measures with the reference measure: Modification of Diet in Renal Disease 4-variable formula, Chronic Kidney Disease Epidemiology Collaboration equation, Cockcroft-Gault formula and cystatin C- derived estimates. Detailed assessment of body build and composition was performed using anthropometric measurements, skinfold thicknesses, bioelectrical impedance and a sub-study used dual-energy X-ray absorptiometry. A

  2. Programmed defects study on masks for 45nm immersion lithography using the novel AIMS 45-193i

    NASA Astrophysics Data System (ADS)

    Scherübl, Thomas; Dürr, Arndt C.; Böhm, Klaus; Birkner, Robert; Richter, Rigo; Strößner, Ulrich

    2007-02-01

    Mask manufacturing for the 45nm node for hyper NA lithography requires tight defect and printability control at small features sizes. The AIMS TM1 technology is a well established methodology to analyze printability of mask defects, repairs and critical features by scanner emulation. With the step towards hyper NA imaging by immersion lithography the AIMS TM technology has been faced with new challenges like vector effects, polarized illumination and tighter specs for repeatability and tool stability. These requirements pushed the development of an entirely new AIMS TM generation. The AIMS TM 45-193i has been designed and developed by Carl Zeiss to address these challenges. A new mechanical platform with a thermal and environmental control unit enables high tool stability. Thus a new class of specification becomes available. The 193nm optical beam path together with an improved beam homogenizer is dedicated to emulate scanners up to 1.4 NA. New features like polarized illumination and vector effect emulation make the AIMS TM 45- 193i a powerful tool for defect disposition and scanner emulation for 45nm immersion lithography. In this paper results from one of the first production tools will be presented. Aerial images from phase shifting and binary masks with different immersion relevant settings will be discussed. Also, data from a long term repeatability study performed on masks with programmed defects will be shown. This study demonstrates the tool's ability to perform defect disposition with high repeatability. It is found that the tool will fulfill the 45nm node requirements to perform mask qualification for production use.

  3. Studies Spotlight Charter Schools Aimed at Diversity

    ERIC Educational Resources Information Center

    Zubrzycki, Jaclyn

    2012-01-01

    Nearly six decades after "Brown" v. "Board of Education," the landmark U.S. Supreme Court decision that ushered in an era of efforts to integrate public schools, charter school advocates and researchers are shining a light on a number of those independent public schools that are integrated by design. Two new reports--one from the National Alliance…

  4. Reconceptualising public acceptability: A study of the ways people respond to policies aimed to reduce alcohol consumption

    PubMed Central

    Cohn, Simon

    2015-01-01

    The issue of public acceptability of health policies is key if they are to have significant and lasting impact. This study, based on focus groups conducted in England, examines the ways people responded to, and made sense of, policy ideas aimed at reducing alcohol consumption. Although effective policies were supported in the abstract, specific proposals were consistently rejected because they were not thought to map onto the fundamental causes of excessive drinking, which was not attributed to alcohol itself but instead its cultural context. Rather than being influenced by the credibility of evidence, or assessed according to likely gains set against possible losses, such responses were established dynamically as people interacted with others to make sense of the topic. This has significant implications for policy-makers, suggesting that existing beliefs and knowledge need to be taken into account as potentially productive rather than obstructive resources. PMID:25769693

  5. Objectives of Financial Statements. Report of the Study Group on the Objectives of Financial Statements.

    ERIC Educational Resources Information Center

    American Inst. of Certified Public Accountants, New York, NY.

    This report discusses the objectives of financial statements. Emphasis is placed on the function of objectives; users, their goals, and their information needs; the primary enterprise goal and earning power; accountability and financial statements; financial statements--reporting on the goal attainment of business enterprises; financial…

  6. Absorption and thermal study of dental enamel when irradiated with Nd:YAG laser with the aim of caries prevention

    NASA Astrophysics Data System (ADS)

    Boari, H. G. D.; Ana, P. A.; Eduardo, C. P.; Powell, G. L.; Zezell, D. M.

    2009-07-01

    It is widely recognized that Nd:YAG can increase enamel resistance to demineralization; however, the safe parameters and conditions that enable the application of Nd:YAG laser irradiation in vivo are still unknown. The aim of this study was to determine a dye as a photoabsorber for Nd:YAG laser and to verify in vitro a safe condition of Nd:YAG irradiation for caries prevention. Fifty-eight human teeth were selected. In a first morphological study, four dyes (waterproof India ink., iron oxide, caries indicator and coal paste) were tested before Nd:YAG laser irradiation, under two different irradiation conditions: 60 mJ/pulse and 10 Hz (84.9 J/cm2); 80 mJ/pulse and 10 Hz (113.1 J/cm2). In a second study, the enamel surface and pulp chamber temperatures were evaluated during laser irradiations. All dyes produced enamel surface melting, with the exception of the caries indicator, and coal paste was the only dye that could be completely removed. All irradiation conditions produced temperature increases of up to 615.08°C on the enamel surface. Nd:YAG laser irradiation at 60 mJ/pulse, 10 Hz and 84.9 J/cm2 promoted no harmful temperature increase in the pulp chamber (ANOVA, p < 0.05). Among all dyes tested, the coal paste was an efficient photoabsorber for Nd:YAG irradiation, considered feasible for clinical practice. Nd:YAG laser at 84.9 J/cm2 can be indicated as a safe parameter for use in caries prevention.

  7. Aeronomy of Ice in the Mesosphere (AIM)

    NASA Technical Reports Server (NTRS)

    2003-01-01

    The overall goal of the Aeronomy of Ice in the Mesosphere (AIM) experiment is to resolve why Polar Mesospheric Clouds form and why they vary. By measuring PMCs and the thermal, chemical and dynamical environment in which they form, we will quanti@ the connection between these clouds and the meteorology of the polar mesosphere. In the end, this will provide the basis for study of long-term variability in the mesospheric climate and its relationship to global change. The results of AIM will be a rigorous validation of predictive models that can reliably use past PMC changes and present trends as indicators of global change. The AIM goal will be achieved by measuring PMC extinction, brightness, spatial distribution, particle size distributions, gravity wave activity, dust influx to the atmosphere and precise, vertical profile measurements of temperature, H20, C&, 0 3 , C02, NO. and aerosols. These data can only be obtained by a complement of instruments on an orbiting spacecraft (S/C).

  8. The Effectiveness of an Innovative Intervention Aimed at Reducing Binge Drinking among Young People: Results from a Pilot Study

    ERIC Educational Resources Information Center

    Coleman, Lester; Ramm, Josephine; Cooke, Richard

    2010-01-01

    Aims: To assess the effectiveness of a digital-story intervention (short videos made by young people) seeking to reduce the prevalence of young people's binge drinking in Caerphilly. Method: A quasi-experimental design was adopted with three intervention sites and one control site providing the sample (mainly aged 14-15 years). Three rounds of…

  9. Towards Formulating Goals, Aims, and Objectives of Secondary Education for the Twenty-First Century. Final Report of a Regional Seminar on Goals, Aims and Objectives of Secondary Education in Asia and the Pacific (Tokyo, Japan, October 16-31, 1991).

    ERIC Educational Resources Information Center

    National Inst. for Educational Research, Tokyo (Japan).

    A regional seminar examined and defined the goals of secondary education in countries of the Asia and Pacific region seminar; it also analyzed causes for changes in secondary education goals and emerging trends. A total of 20 participants from the following countries--Australia, Bangladesh, China, India, Indonesia, Japan, Malaysia, Nepal, New…

  10. Aims and Control of the Universities: A Comparative Study of Academic Governance in Sweden and the United States.

    ERIC Educational Resources Information Center

    Duster, Troy

    This is a comparative study of university control in Sweden and the United States with particular attention to the question of what difference it makes as to which segment of the university community controls a particular aspect of university life and university function. It is an exploration of the problem of the relationship between the…

  11. Animated View of the AIM Mission

    NASA Video Gallery

    The Aeronomy of Ice in the Mesosphere (AIM) mission will provide the first detailed exploration of Earth's unique and elusive noctilucent or night shining clouds that are found literally on the "ed...

  12. Interactive web visualization tools to the results interpretation of a seismic risk study aimed at the emergency levels definition

    NASA Astrophysics Data System (ADS)

    Rivas-Medina, A.; Gutierrez, V.; Gaspar-Escribano, J. M.; Benito, B.

    2009-04-01

    Results of a seismic risk assessment study are often applied and interpreted by users unspecialised on the topic or lacking a scientific background. In this context, the availability of tools that help translating essentially scientific contents to broader audiences (such as decision makers or civil defence officials) as well as representing and managing results in a user-friendly fashion, are on indubitable value. On of such tools is the visualization tool VISOR-RISNA, a web tool developed within the RISNA project (financed by the Emergency Agency of Navarre, Spain) for regional seismic risk assessment of Navarre and the subsequent development of emergency plans. The RISNA study included seismic hazard evaluation, geotechnical characterization of soils, incorporation of site effects to expected ground motions, vulnerability distribution assessment and estimation of expected damage distributions for a 10% probability of exceedance in 50 years. The main goal of RISNA was the identification of higher risk area where focusing detailed, local-scale risk studies in the future and the corresponding urban emergency plans. A geographic information system was used to combine different information layers, generate tables of results and represent maps with partial and final results. The visualization tool VISOR-RISNA is intended to facilitate the interpretation and representation of the collection of results, with the ultimate purpose of defining actuation plans. A number of criteria for defining actuation priorities are proposed in this work. They are based on combinations of risk parameters resulting from the risk study (such as expected ground motion and damage and exposed population), as determined by risk assessment specialists. Although the values that these parameters take are a result of the risk study, their distribution in several classes depends on the intervals defined by decision takers or civil defense officials. These criteria provide a ranking of

  13. Mechanistic studies aimed at the development of single site metal alkoxide catalysts for the production of polyoxygenates from renewable resources.

    SciTech Connect

    Chisholm, Malcolm H.

    2015-12-15

    The work proposed herein follows on directly from the existing 3 year grant and the request for funding is for 12 months to allow completion of this work and graduation of current students supported by DOE. The three primary projects are as follows. 1.) A comparative study of the reactivity of LMg(OR) (solvent), where L= a β-diiminate or pyrromethene ligand, in the ring-opening of cyclic esters. 2.) The homopolymerization of expoxides, particularly propylene oxide and styrene oxide, and their copolymerizations with carbon dioxide or organic anhydrides to yield polycarbonates or polyesters, respectively. 3.) The development of well-defined bismuth (III) complexes for ring-opening polymerizations that are tolerant of both air and water. In each of these topics special emphasis is placed on developing a detailed mechanistic understanding of the ring-opening event and how this is modified by the employment of specific metal and ligand combinations. This document also provides a report on findings of the past grant period that are not yet in the public domain/published and shows how the proposed work will bring the original project to conclusion.

  14. Aiming for the Singing Teacher: An Applied Study on Preservice Kindergarten Teachers' Singing Skills Development within a Music Methods Course

    ERIC Educational Resources Information Center

    Neokleous, Rania

    2015-01-01

    This study examined the effects of a music methods course offered at a Cypriot university on the singing skills of 33 female preservice kindergarten teachers. To systematically measure and analyze student progress, the research design was both experimental and descriptive. As an applied study which was carried out "in situ," the normal…

  15. AIM: Adventures in Movement for the Handicapped.

    ERIC Educational Resources Information Center

    Adventures In Movement for the Handicapped, Inc., Dayton, OH.

    The handbook on Adventures in Movement for the Handicapped (AIM) gives information about general organizational goals and suggests activities for use by volunteer teachers with blind, deaf, crippled, cerebral palsied, mentally retarded, and autistic children at five ability/age levels. General Information given about each handicap usually includes…

  16. An Exploratory Study into the Efficacy of Learning Objects

    ERIC Educational Resources Information Center

    Farha, Nicholas W.

    2009-01-01

    Learning objects have quickly become a widely accepted approach to instructional technology, particularly in on-line and computer-based learning environments. While there is a substantial body of literature concerning learning objects, very little of it verifies their efficacy. This research investigated the effectiveness of learning objects by…

  17. Fire First, Aim Later: A Qualitative Meta-Analytic Study of the Assessment Methods of Professional Learning Communities

    ERIC Educational Resources Information Center

    Lopez Flores, Emily

    2014-01-01

    Research has been conducted to identify and analyze how schools are determining that the activities of their Professional Learning Community (PLC) are directly tied to student achievement as there is currently a gap in the existing literature with regards to this topic. For the purpose of this study, a "successful" PLC was defined as one…

  18. Researchers Weigh Benefits of One Computer per Lap: Studies Aim to Determine the Impact the Technology Has on Student Learning

    ERIC Educational Resources Information Center

    Borja, Rhea R.

    2006-01-01

    Almost one-quarter of school districts nationwide and nine states have invested millions of dollars in "one-to-one" laptop programs, hoping the availability of a computer for every student will improve achievement and other skills. They made those investments despite the fact that research on the impact of such technology on student achievement is…

  19. Theory of Knowledge Aims, Objectives and Assessment Criteria: An Analysis of Critical Thinking Descriptors

    ERIC Educational Resources Information Center

    Hughes, Conrad

    2014-01-01

    This article analyses the construct validity of the International Baccalaureate Diploma Programme's Theory of Knowledge course in the light of claims that it is a course in critical thinking. After discussion around critical thinking--what it is and why it is valuable educationally--the article analyses the extent to which the course aims,…

  20. The whole of intramolecular H-bonding in the isolated DNA nucleoside thymidine. AIM electron density topological study

    NASA Astrophysics Data System (ADS)

    Yurenko, Yevgen P.; Zhurakivsky, Roman O.; Samijlenko, Svitlana P.; Ghomi, Mahmoud; Hovorun, Dmytro M.

    2007-10-01

    Based on comprehensive conformational analysis at the DFT B3LYP/6-31G(d,p) level of theory [Ye.P. Yurenko et al., J. Phys. Chem. B, 111 (2007) 9655] 13 types of intramolecular hydrogen bonds (171 in total number, from 1 to 3 H-bonds per conformer) were identified in the 92 allowed conformers of isolated thymidine, a DNA canonical nucleoside. Weak interactions CH⋯ O, OH⋯ HC and CH⋯ HC were analyzed by all the Koch and Popelier criteria of H-bonding. Quite satisfactory linear correlation was found between Grabowski complex measure of H-bond strength Δcom and Iogansen H-bond energy -Δ H for 17 OH⋯O hydrogen bonds.

  1. Aiming Instruments On The Space Station

    NASA Technical Reports Server (NTRS)

    Estus, Jay M.; Laskin, Robert; Lin, Yu-Hwan

    1989-01-01

    Report discusses capabilities and requirements for aiming scientific instruments carried aboard proposed Space Station. Addresses two issues: whether system envisioned for pointing instruments at celestial targets offers sufficiently low jitter, high accuracy, and high stability to meet scientific requirements; whether it can do so even in presence of many vibrations and other disturbances on Space Station. Salient conclusion of study, recommendation to develop pointing-actuator system including mechanical/fluid base isolator underneath reactionaless gimbal subsystem. This kind of system offers greatest promise of high performance, cost-effectiveness, and modularity for job at hand.

  2. Aims, methods and preliminary findings of the Physical Activity, Nutrition and Allergies in Children Examined in Athens (PANACEA) epidemiological study

    PubMed Central

    Priftis, Kostas N; Panagiotakos, Demosthenes B; Anthracopoulos, Michael B; Papadimitriou, Anastasios; Nicolaidou, Polyxeni

    2007-01-01

    Background To determine the prevalence of asthma symptoms in a sample of Greek children aged 10–12 years, and to evaluate these rates in relation to anthropometric, lifestyle characteristics and dietary habits. Methods During 2006, 700 schoolchildren (323 male and 377 female), aged 10–12 years (4th to 6th school grade), were selected from 18 schools located in the greater Athens area. The schools were randomly selected from a list provided by the regional educational offices. To achieve a representative sample the schools enrolled were selected from various region of the Athens area. For each child a questionnaire was completed that was developed for the purposes of the study to retrieve information on: age, sex, school class, other socio-demographic characteristics, anthropometric measurements, dietary habits (through a semi-quantitative Food Frequency Questionnaire) and physical activity status; the presence of asthma and allergies was assessed by the standard ISAAC questionnaire. Results The prevalence of wheezing in the past was 25% in boys and 19% in girls, while the prevalence of current wheezing was 9.0% in boys and 5.8% in girls. The prevalence of any asthma symptoms was 27.6% in boys and 20.4% in girls. Multiple logistic regression analysis revealed that increased body weight and sedentary lifestyle is associated with asthma symptoms only in boys. Conclusion The present cross-sectional study cannot establish causal relationships between asthma and increased body weight of schoolchildren; however, our findings underline the associations between asthma, increased body weight, and physical activity at population level, and urge for actions that should be taken by public health policy makers in order to prevent these conditions among children. PMID:17610743

  3. The aim and philosophy of patient monitoring

    PubMed Central

    Stewart, J. S. S.

    1970-01-01

    The history of monitoring is traced from ancient times until the invention of transducers and computers. The relevance of progress in resuscitation is emphasized. The more recent evolution of electromedical apparatus is considered from single signal detection, display and alarm to multiple signal processing, trend analysis and diagnosis. The aim of patient monitoring is to give warning of early or dangerous deterioration and to achieve this by obtaining an optimal compromise involving many design factors, clinical, engineering and economic. A new philosophy is illustrated by the specification and development of the Lifeline patient monitor. The translation of clinical diagnoses into electronic switching logic is of particular importance. PMID:4920275

  4. Development of tag-free photoprobes for studies aimed at identifying the target of novel Group A Streptococcus antivirulence agents

    PubMed Central

    Yestrepsky, Bryan D.; Kretz, Colin A.; Xu, Yuanxi; Holmes, Autumn; Sun, Hongmin; Ginsburg, David; Larsen, Scott D.

    2014-01-01

    We previously reported the identification and development of novel inhibitors of streptokinase (SK) expression by Group A Streptococcus (GAS), originating from a high throughput cell-based phenotypic screen. Although phenotypic screening is well-suited to identifying compounds that exert desired biological effects in potentially novel ways, it requires follow-up experiments to determine the macromolecular target(s) of active compounds. We therefore designed and synthesized several classes of chemical probes for target identification studies, guided by previously established structure-activity relationships. The probes were designed to first irreversibly photolabel target proteins in the intact bacteria, followed by cell lysis and click ligation with fluorescent tags to allow for visualization on SDS-PAGE gels. This stepwise, “tag-free” approach allows for a significant reduction in molecular weight and polar surface area compared to full-length fluorescent or biotinylated probes, potentially enhancing membrane permeability and the maintenance of activity. Of the seven probes produced, the three most biologically active were employed in preliminary target identification trials. Despite the potent activity of these probes, specific labeling events were not conclusively observed due to a considerable degree of nonspecific protein binding. Nevertheless, the successful synthesis of potent biologically active probe molecules will serve as a starting point for initiating more sensitive methods of probe-based target identification. PMID:24559768

  5. Work, the Aims of Life and the Aims of Education: A Reply to Clarke and Mearman

    ERIC Educational Resources Information Center

    Winch, Christopher

    2004-01-01

    The main points made by Clarke and Mearman about Winch's article, 'The Economic Aims of Education,' are taken up and discussed. My argument is that work is not necessarily a disutility, although paid employment can be when it is undertaken in conditions that are not fulfilling. Life aims are not the same as educational aims, although educational…

  6. The European Atherosclerosis Research Study (EARS): design and objectives.

    PubMed

    1994-06-01

    The European Atherosclerosis Research Study--EARS--is a multicentre collaborative project sponsored by the European Community. Its main objective is to study, in young people, the biological expression of a paternal history of premature acute myocardial infarction (AMI) and the relative share of heredity and environment in this expression. In 14 centres in 11 European countries, the offspring of fathers who suffered from a documented AMI before the age of 55 years (cases) are compared with age- and sex-matched control individuals. Genetic variables (restriction fragment length polymorphisms of candidate genes), lifestyle variables and biochemical variables that are known or suspected to play a role in the development of coronary heart disease (CHD), are studied. The cultural and ethnic diversity within Europe allows a thorough investigation of the relative importance and the potential interactions of genetics and environment in the pathogenesis of CHD. A standardized core methodology and centralized storage of blood samples with particular types of analyses systematically carried out in one or a few specialized laboratories, from a strong basis for valid cross-cultural analyses. The results of this study will offer new clues for the modelling of individual risk for developing CHD. PMID:7960370

  7. The functional neuroanatomy of object agnosia: A case study

    PubMed Central

    Konen, Christina S.; Behrmann, Marlene; Nishimura, Mayu; Kastner, Sabine

    2016-01-01

    Summary Cortical re-organization of visual and object representations following neural injury was examined using fMRI and behavioral investigations. We probed the visual responsivity of the ventral visual cortex of an agnosic patient who was impaired at object recognition following a lesion to the right lateral fusiform gyrus. In both hemispheres, retinotopic mapping revealed typical topographic organization and visual activation of early visual cortex. However, visual responses, object-related and -selective responses were reduced in regions immediately surrounding the lesion in the right hemisphere, and also, surprisingly, in corresponding locations in the structurally intact left hemisphere. In contrast, hV4 of the right hemisphere showed expanded response properties. These findings indicate that the right lateral fusiform gyrus is critically involved in object recognition and that an impairment to this region has widespread consequences for remote parts of cortex. Finally, functional neural plasticity is possible even when a cortical lesion is sustained in adulthood. PMID:21745637

  8. Learning Objects in the Study of Mathematical Topics

    NASA Astrophysics Data System (ADS)

    Macedo, Josué Antunes de; Nunes, Taise Costa de Souza; Voelzke, Marcos Rincon

    2015-12-01

    This work is the result of a survey that aimed to produce Applets(animations) using the GeoGebra software applied to the study of trigonometric functions. We opted for the choice of this software, because of its easy usability, have nice interface and is very didactic, allowing the realization of a simple graphic to complex constructions. The choice of the contents of trigonometric functions, was due to the concern of many students want to learn the appropriate behavior involving these functions, because in practice beyond the calculations, the students require two-dimensional images to construct the graphics, Therefore, the use of the GeoGebra software can assist in building and viewing these charts. We used a metodology qualiquantitative to collection and data analysis, based on the application of questionnaires and observations having as use of didactic engineering for the formulation of didactic sequences. To the application of this methodology, a minicurs was given, with twenty hours, to the Mathematic and Physic students at the Federal Institute of Education, Science and Technology in the North of Minas Gerais (IFNMG), Campus Januária. The results were found satisfactory, since the use of GeoGebra software provided a significant learning for the academics.

  9. A Pilot Study Aiming to Promote Parents' Understanding of Learning Assessments at the Elementary Level

    ERIC Educational Resources Information Center

    Deslandes, Rollande; Rivard, Marie-Claude

    2013-01-01

    The new Québec curriculum is different from other curriculum reforms in that it is based on a competency approach, both cross-curricular and disciplinary. It thus means a move from knowledge-based to competency-based assessments which represents a real challenge to parents who may find it hard to understand learning assessments and their…

  10. Aims, Modes, and the Continuum of Discourse.

    ERIC Educational Resources Information Center

    Beale, Walter H.

    A framework for the study of discourse, based on the analysis of three superordinate features of discourse (asymmetry, hierarchy, and continuum), is proposed in this paper. The paper begins by noting the confusion in terminology that exists in the world of composition pedagogy and theory; pointing to the need for a framework for testing,…

  11. Overview of the TRO-pico campaign aiming at studying of the impact of convective overshooting on the stratospheric water budget

    NASA Astrophysics Data System (ADS)

    Rivière, Emmanuel; Pommereau, Jean-Pierre; Amarouche, Nadir; Ghysels, Mélanie; Stoeffler, Clara; Khaykin, Sergey; Berthelier, Jean-Jacques; Renard, Jean-Baptiste; Wienhold, Franck; Cairo, Francesco; Di Donfrancesco, Guido; Held, Gerhard

    2013-04-01

    (SMOP) covering one complete wet season during which water vapour profiles are measured regularly for studying their seasonal variability, and ii) an intensive observation period (IOP) during the most convectively intense summer period when measurements of all above parameters are performed close to or above thunderstorms. After a short presentation of objectives and instrumentation involved, the main results from the complete TRO-pico campaign will be shown, including the most intense period of convection and the transition period between the dry and the wet seasons.

  12. Theoretical studies of the outer envelopes of young stellar objects

    NASA Technical Reports Server (NTRS)

    Hartmann, Lee

    1992-01-01

    With the Monte Carlo code developed by Whitney and Hartmann, a series of models was computed of scattering in disks around young stellar objects. The code calculates scattering by dust, including polarization, in arbitrary geometries. By computing model images, it was found that disk, by themselves, around young stellar objects would be very difficult to detect with present day imaging techniques. In comparing these images to observations of young stellar objects which show diffuse structure, little resemblance was found. A flared disk system will only give high polarization when viewed edge-on, and the position angle is always oriented perpendicular to the disk plane. This suggests that an envelope, perhaps the remnant infalling envelope, must be present to scatter more stellar light than a disk can, and obscure the star at many inclinations. A grid was computed of models of scattering in a disk+envelope system. Evidence is presented that the wind of the pre-main sequence object FU Orionis arises from the surface of the luminous prostellar accretion disk. A disk wind model calculated assuming radiative equilibrium explains the differential behavior of the observed asymmetrical absorption line profiles. The model predicts that strong lines should be asymmetric and blueshifted, while weak lines should be symmetric and doubled peaked due to disk rotation, in agreement with observations.

  13. Study of air masses trajectories during the TRO-pico campaign aiming at studying of the impact of convective overshooting on the stratospheric water budget

    NASA Astrophysics Data System (ADS)

    Mappe, Irene; Riviere, Emmanuel; Khaykin, Sergey; Ghysels, Mélanie; Stoeffler, Clara; Amarouche, Nadir; Durry, Georges; Held, Gerhard

    2014-05-01

    Water vapor directly affects the climate as greenhouse gas emissions, but also indirectly by the formation of other essential elements of radiative forcing as aerosols, clouds of ice. In addition, water has a significant role in the chemical composition, the balance of ozone and the oxidizing capacity of the atmosphere. Transfers of water vapor in the troposphere to the stratosphere are one of the major scientific challenges in modeling the stratosphere and climate. The TRO-pico small balloon campaign took place in Bauru (22.3 ° S) in southern Brazil during two convective seasons. Its main objective was to study the exchange of water vapor between the upper troposphere and lower stratosphere, and better understand the role of overshooting convection in the moistening of the lower stratosphere and its variability at the local scale to infer a typical impact at a larger scale. Here we focus on the purely convective seasons of the campaign, with a first period in March 2012 and a second in Jan-Feb 2013, during which, in addition to convective tracers measurements (methane, O3…) H2O was intensively sampled by two different in situ hygrometers : Pico-SDLA H2O and FLASH-B. Here we investigated all the measurements gathered close to deep convective events and analyze them in term of potential signature of overshooting convection in the lower stratosphere, to put to the fore possible impact at the wet season time scale. The approach is the use of a trajectory model (HYsplit) running with the GDAS analyses, the different H2O profile from both instruments, echo top from the Bauru S-Band radar highlighting any potential overshoot occurrence in the vicinity of the balloon flight earlier during the day. For each local maximum of H2O, a back trajectory is computed from the balloon position. It is checked if the back trajectory cross an overshooting cell seen by the Bauru radar, and matches it in time and maximum altitude Here we use a total of 8 vertical profiles of H2O from

  14. First results from the TRO-pico campaign aiming at studying the impact of convective overshooting on the stratospheric water budget

    NASA Astrophysics Data System (ADS)

    Rivière, E. D.; Pommerau, J.-P.; Held, G.; Amarouche, N.; Ghysels, M.; Khaykin, S.; Berthelier, J.-J.; Renard, J.-B.; Cairo, F.; Durry, G.; Di Donfrancesco, G.

    2012-04-01

    Two processes are competing in the control of water vapor concentration in the tropical stratosphere: i) The so-called cold trap that is the slow ascent of water vapour in the TTL (Tropical Tropopause Layer) followed by ice crystal freezing and sedimentation leading to the drying of air entering the stratosphere and ii) convective overshooting that injects ice crystals sublimating in the stratosphere, eventually followed by further condensation and sedimentation. In contrast with the large-scale cold trap mechanism, overshooting towers are small in size and fast, but relatively frequent processes. Even if the first is frequently thought to be the main process controlling the amount of water in the stratosphere, the importance of overshooting, highly dependent on the frequency of the events, is still unknown. The aim of the TRO-pico project, funded by the French ANR, is to characterize the variability and frequency of convective water injections, its contribution at the regional wet season timescale, and to improve the understanding of their role with respect to the cold trap at a wider scale. The project is based on a small balloon campaign in Bauru (22.3 S) in Southeast Brazil, from the end of January 2012 to December 2012, involving a series of light-weight payloads, including Pico-SDLA laser (H2O or CH4) and FLASH Lyman alpha hygrometers, a mini-SOAZ spectrometer for O3, NO2, H2O, and BrO, an AICEP (Electric field and Lightning) sensor, and COBALD and LOAC aerosol instruments, combined with ground based radar and lidar measurements, satellite observations from CALIPSO, MLS, Megha-Tropiques and adequate modeling, that is, of all parameters sensitive to convective intensity. TRO-pico is a two time-scale campaign: i) a Six Month Observation Period (SMOP) covering a complete wet season during which water vapour profiles will be measured regularly for studying its variability and seasonal change, and ii) an intensive observation period (IOP) during the most

  15. Nutrition education aimed at toddlers: an intervention study.

    PubMed

    Horodynski, Mildred A; Stommel, Manfred

    2005-01-01

    Weight problems in children are increasing at an alarming rate, especially among low-income populations. This concern requires effective strategies to promote healthy eating. A quasi-experiment was used to assess the effectiveness of an intervention, Nutrition Education Aimed at Toddlers (NEAT), aimed at enhancing parent-toddler feeding practices. The NEAT intervention comprises four nutrition lessons and structured reinforcements over 6 months. A convenience sample of 135 low-income families participated in the study up to the first data collection wave. Complete data were available for 43 parent-toddler dyads in the intervention and 53 dyads in the control group. The results show that, compared to the controls, caregivers exposed to the intervention had significantly higher knowledge scores concerning toddler feedings. No statistically significant differences were found for measures of child and parent mealtime behaviors. Because it is generally easier to change knowledge than actual behaviors, our study results demonstrate the need to focus on other avenues to enhance parents' ability to feed toddlers appropriately. PMID:16295151

  16. Seeing is believing? A mixed-methods study exploring the quality and perceived trustworthiness of online information about chronic conditions aimed at children and young people.

    PubMed

    McPherson, Amy C; Gofine, Miriam L; Stinson, Jennifer

    2014-01-01

    The numbers of children and young people with chronic conditions are increasing. While their information needs may vary, providing health care information can have considerable benefits, including better emotional health, less distress during treatments, and greater satisfaction with medical care. The Internet is increasingly being used to communicate health-related information to children about a range of chronic conditions. However, the quality of such websites is underexplored. Thus, the objectives of this study were to evaluate the reliability and quality of online information for children about chronic conditions using a standardized evaluation tool, and to explore children's and young people's perceptions of quality and trustworthiness regarding online health information. The study consisted of two phases. In Phase 1, websites about common pediatric chronic conditions aimed at children and containing treatment or management options were identified and the quality assessment tool DISCERN was completed. Test-retest and interrater reliability were calculated. In Phase 2, two focus groups with laptop computers were conducted with children and young people with a chronic condition to explore their perceptions of trustworthiness of online health information. In Phase 1, 165 websites were identified and 100 met the criteria and were assessed. The mean DISCERN score of all sites was 48.16 out of 75 (SD = 7.97, range 28-71, min 15 to max 75). Quality scores varied widely across the sample. The internal consistency and interrater reliability scores were both lower than previously reported in studies using the DISCERN to assess information for adults. In Phase 2, two focus groups with a total of six participants aged 11-23 years revealed a relative lack of concern about the quality and trustworthiness of online health information. Older participants reported judging the source and authorship of websites, but other participants did not question the source of the

  17. Experimental stand for studying the impact of laser-accelerated protons on biological objects

    NASA Astrophysics Data System (ADS)

    Burdonov, K. F.; Eremeev, A. A.; Ignatova, N. I.; Osmanov, R. R.; Sladkov, A. D.; Soloviev, A. A.; Starodubtsev, M. V.; Ginzburg, V. N.; Kuz'min, A. A.; Maslennikova, A. V.; Revet, G.; Sergeev, A. M.; Fuchs, J.; Khazanov, E. A.; Chen, S.; Shaykin, A. A.; Shaikin, I. A.; Yakovlev, I. V.

    2016-04-01

    An original experimental stand is presented, aimed at studying the impact of high-energy protons, produced by the laser-plasma interaction at a petawatt power level, on biological objects. In the course of pilot experiments with the energy of laser-accelerated protons up to 25 MeV, the possibility is demonstrated of transferring doses up to 10 Gy to the object of study in a single shot with the magnetic separation of protons from parasitic X-ray radiation and fast electrons. The technique of irradiating the cell culture HeLa Kyoto and measuring the fraction of survived cells is developed. The ways of optimising the parameters of proton beams and the suitable methods of their separation with respect to energy and transporting to the studied living objects are discussed. The construction of the stand is intended for the improvement of laser technologies for hadron therapy of malignant neoplasms.

  18. Objectives, Design, and History of the National Longitudinal Study.

    ERIC Educational Resources Information Center

    Davis, J. A.; Collins, Elmer

    The National Longitudinal Study of the High School Class of 1972 (NLS) is a federally supported longitudinal study of a national sample of some 23,000 young people first surveyed as high school seniors in the spring of 1972. The historical precedents of such a study include the work of Friend and Haggert in a Boston settlement house, Louis…

  19. Another Look at the Aims of Education

    ERIC Educational Resources Information Center

    DeCiccio, Al

    2015-01-01

    The author was able to hear Stanley Fish speak at the annual meeting of the Association of American Colleges and Universities in January 2004. Fish, a literary critic, had become dean of arts and sciences at the University of Illinois at Chicago (UIC)--a position he has now vacated. Fish has published widely, usually upholding the ideals of our…

  20. The Origins and Aims of Epistemics

    ERIC Educational Resources Information Center

    Meredith, G. Patrick

    1972-01-01

    First of two articles describing the nature and historical development of the author's work on Epistemics" which he originally conceived as the science of the structure and transmission of human knowledge" and later elaborated to enable separate emphasis to be given to the human and instrumental aspect of knowledge transmission. (Editor/MB)

  1. The Future of Vocational Psychology: Aiming High.

    ERIC Educational Resources Information Center

    Fouad, Nadya A.

    2001-01-01

    The strengths of vocational psychology include quantitative foundations, theory-driven research, and focus on vocational assessment. Weaknesses are overemphasis on quantitative methods, lack of context, and class-bound perceptions of work. Threats include appropriation by related disciplines and the practice of vocational counseling by those…

  2. Ready, Fire, Aim: The College Campus Gunfight

    ERIC Educational Resources Information Center

    Birnbaum, Robert

    2012-01-01

    Twenty-three State legislatures in 2011 considered bills to permit the carrying of firearms at their public institutions of higher education, and some public colleges in at least six states now allow weapons on college grounds or in college buildings. The lawful possession of guns on campus is a recent and limited phenomenon, but decisions by the…

  3. An objective reference system for studying rings in the ocean

    NASA Astrophysics Data System (ADS)

    Castelão, Guilherme P.; Irber, Luiz C.; Villas Boas, Ana B. M.

    2013-12-01

    Rings are marine vortices with a scale of hundreds of kilometers that can last for months, whose associated transport and mixing play an important role in the ocean dynamics. Such features are traditionally treated as a geostrophic flow, but since the centrifugal acceleration is not negligible in the inner core, the cyclo-geostrophic balance is a better approximation for the rings. In the present work, we describe a novel objective technique to identify the ring center, which is used as the origin of a convenient framework to handle rings under the cyclo-geostrophic balance. Furthermore, we correct the velocity field by the translation to isolate the swirl movement, a procedure ignored by other methodologies. We show that the lack of such correction would lead to an error of 30 km on the center definition of a ship surveyed North Brazil Current Ring with 160 km of radius. Another distinct characteristic of our approach is the flexibility in the spatio-temporal structure of the data, because it allows for ungridded data, an important ability for in situ observations. That also enables the use of a hybrid dataset composed from different instruments. The error on the Monte Carlo experiments to identify the center of the propagating ring is less than 10 km, and depends on the level of noise, sampling strategy, and strength of the ring, among other factors. This technique was fully implemented in PyRings, an open Python library with a collection of procedures to handle oceanic rings and mesoscale eddies in general.

  4. Social Studies Objectives, K-12.

    ERIC Educational Resources Information Center

    Dependents Schools (DOD), Washington, DC.

    Six objectives which form the framework of a K-12 social studies program of Department of Defense Dependents Schools are outlined. The objectives are to evaluate the relationship between human beings and their social, natural, and man-made environment; analyze the origins and interrelationships of beliefs, values, and behavior patterns; solve…

  5. The United Kingdom Childhood Cancer Study: objectives, materials and methods

    PubMed Central

    2000-01-01

    An investigation into the possible causes of childhood cancer has been carried out throughout England, Scotland and Wales over the period 1991–1998. All children known to be suffering from one or other type of the disease over periods of 4–5 years have been included, and control children matched for sex, age and area of residence have been selected at random from population registers. Information about both groups of children (with and without cancer) has been obtained from parental questionnaires, general practitioners' and hospital records, and from measurement of the extent of exposure to radon gas, terrestrial gamma radiation, and electric and magnetic fields. Samples of blood have also been obtained from the affected children and their parents and stored. Altogether 3838 children with cancer, including 1736 with leukaemia, and 7629 unaffected children have been studied. Detailed accounts are given of the nature of the information obtained in sections describing the general methodology of the study, the measurement of exposure to ionizing and non-ionizing radiation, the classification of solid tumours and leukaemias, and the biological material available for genetic analysis. © 2000 Cancer Research Campaign PMID:10737392

  6. A comparison of subjective and objective measures of physical activity from the Newcastle 85+ study

    PubMed Central

    Innerd, Paul; Catt, Michael; Collerton, Joanna; Davies, Karen; Trenell, Michael; Kirkwood, Thomas B. L.; Jagger, Carol

    2015-01-01

    Background: Little is known about physical activity (PA) in the very old, the fastest growing age group in the population. We aimed to examine the convergent validity of subjective and objective measures of PA in adults aged over 85 years. Methods: A total of 484 participants aged 87–89 years recruited to the Newcastle 85+ study completed a purpose-designed physical activity questionnaire (PAQ), which categorised participants as mildly active, moderately active and very active. Out of them, 337 participants wore a triaxial, raw accelerometer on the right wrist over a 5–7-day period to obtain objective measures of rest/activity, PA intensity and PA type. Data from subjective and objective measurement methods were compared. Results: Self-reported PA was significantly associated with objective measures of the daily sedentary time, low-intensity PA and activity type classified as sedentary, activities of daily living and walking. Objective measures of PA were significantly different when low, moderate and high self-reported PA categories were compared (all P < 0.001). Conclusion: The Newcastle 85+ PAQ demonstrated convergent validity with objective measures of PA. Our findings suggest that this PAQ can be used in the very old to rank individuals according to their level of total PA. PMID:26018999

  7. Object motion analysis study

    NASA Technical Reports Server (NTRS)

    1974-01-01

    The use of optical data processing (ODP) techniques for motion analysis in two-dimensional imagery was studied. The basic feasibility of this approach was demonstrated, but inconsistent performance of the photoplastic used for recording spatial filters prevented totally automatic operation. Promising solutions to the problems encountered are discussed, and it is concluded that ODP techniques could be quite useful for motion analysis.

  8. The Use of Metaphorical Connotation of Inanimate Objects to Describe People by Speakers of Jordanian Arabic: A Pragmatic Study

    ERIC Educational Resources Information Center

    Al Soudi, Layth

    2015-01-01

    This paper aims to investigate the use of connotations of inanimate objects to describe people by speakers of Jordanian Arabic. Its main goal is to analyze the positive and negative connotative meanings of inanimate object used to describe people in Jordan. Besides, the contribution of gender in making connotative meanings. The study provides a…

  9. Study Protocol – Diabetes and related conditions in urban Indigenous people in the Darwin, Australia region: aims, methods and participation in the DRUID Study

    PubMed Central

    Cunningham, Joan; O'Dea, Kerin; Dunbar, Terry; Weeramanthri, Tarun; Zimmet, Paul; Shaw, Jonathan

    2006-01-01

    Background Diabetes mellitus is a serious and increasing health problem in Australia and is a designated national health priority. Diabetes and related conditions represent an even greater health burden among Indigenous Australians (Aborigines and Torres Strait Islanders), but there are critical gaps in knowledge relating to the incidence and prevalence, aetiology, and prevention of diabetes in this group, including a lack of information on the burden of disease among Indigenous people in urban areas. The DRUID Study (Diabetes and Related conditions in Urban Indigenous people in the Darwin region) was designed to address this knowledge gap. Methods/design The study was conducted in a specified geographic area in and around Darwin, Australia. Eligible participants underwent a health examination, including collection of blood and urine samples, clinical and anthropometric measurements, and administration of questionnaires, with an additional assessment for people with diabetes. The study was designed to incorporate local Indigenous leadership, facilitate community engagement, and provide employment and training opportunities for local Indigenous people. A variety of recruitment methods were used. A total of 1,004 eligible people gave consent and provided at least one measurement. When compared with census data for the Indigenous population living in the study area, there was a marked under-representation of males, but no substantial differences in age, place of residence, Indigenous group, or household income. Early participants were more likely than later participants to have previously diagnosed diabetes. Discussion Despite lower than anticipated recruitment, this is, to our knowledge, the largest study ever conducted on the health of Indigenous Australians living in urban areas, a group which comprises the majority of Australia's Indigenous population but about whose health and wellbeing relatively little is known. The study is well-placed to provide new

  10. Numerical Study of the Location of the Microwave Imaging Reflectometer Object Plane

    NASA Astrophysics Data System (ADS)

    Ignatenko, Maxim; Mase, Atsushi; Bruskin, Leonid; Kogi, Yuichiro; Hojo, Hitoshi

    This paper is devoted to numerical study of the location of the imaging optics object plane. The simulation shows that in the case of the plane plasma cutoff, the object plane is located at the virtual cutoff position defined by E. Mazzucato [Nuclear Fusion 45, 203 (2001)], while in the case of cylindrical plasma, the object plane is shifted toward the cutoff position.

  11. An intervention program with the aim to improve and maintain work productivity for workers with rheumatoid arthritis: design of a randomized controlled trial and cost-effectiveness study

    PubMed Central

    2012-01-01

    Background Workers with rheumatoid arthritis (RA) often experience restrictions in functioning at work and participation in employment. Strategies to maintain work productivity exist, but these interventions do not involve the actual workplace. Therefore the aim of this study is to investigate the (cost)effectiveness of an intervention program at the workplace on work productivity for workers with RA. Methods/design This study is a randomized controlled trial (RCT) in specialized rheumatology treatment centers in or near Amsterdam, the Netherlands. Randomisation to either the control or the intervention group is performed at patient level. Both groups will receive care as usual by the rheumatologist, and patients in the intervention group will also take part in the intervention program. The intervention program consists of two components; integrated care, including a participatory workplace intervention. Integrated care involves a clinical occupational physician, who will act as care manager, to coordinate the care. The care manager has an intermediate role between clinical and occupational care. The participatory workplace intervention will be guided by an occupational therapist, and involves problem solving by the patient and the patients’ supervisor. The aim of the workplace intervention is to achieve consensus between patient and supervisor concerning feasible solutions for the obstacles for functioning at work. Data collection will take place at baseline and after 6 and 12 months by means of a questionnaire. The primary outcome measure is work productivity, measured by hours lost from work due to presenteeism. Secondary outcome measures include sick leave, quality of life, pain and fatigue. Cost-effectiveness of the intervention program will be evaluated from the societal perspective. Discussion Usual care of primary and outpatient health services is not aimed at improving work productivity. Therefore it is desirable to develop interventions aimed at

  12. Overview of the TRO-pico campaign aiming at studying of the impact of convective overshooting on the stratospheric water budget: first highlights

    NASA Astrophysics Data System (ADS)

    Rivière, Emmanuel; Pommereau, Jean-Pierre; Amarouche, Nadir; Khaykhin, Sergey; Ghysels, Melanie; Mappe-Fogaing, Irene; Stoeffler, Clara; Toledo-Tarasco, Daniel; Rannou, Pascal; Renard, Jean-Baptiste; Wienhold, Franck; Durry, Georges; Held, Gerhard

    2014-05-01

    Two processes are competing in the control of water vapor concentration in the tropical stratosphere: i) The so-called cold trap that is the slow ascent of water vapour in the TTL followed by ice crystal freezing and sedimentation leading to the drying of air entering the stratosphere and ii) convective overshooting that injects ice crystals sublimating in the stratosphere, eventually followed by further condensation and sedimentation. In contrast with the large-scale cold trap mechanism, overshooting towers are small size, fast but relatively frequent processes. Even if the first is frequently thought to be the main process controlling the amount of water in the stratosphere, the importance of overshooting, highly dependent on the frequency of the events, is still unknown. The aim of the TRO-pico project, supported by the French ANR, is to characterize the variability and frequency of convective water injections, its contribution at the regional wet season timescale, and to improve the understanding of their role with respect to the cold trap at a wider scale. The project is based on a small balloon campaign that took place in Bauru (22.3°S) in S-E Brazil, in March 2012 and from November 2012 to March 2013 (most of the wet season) with a peak phase in January-February 2013 (during the most active convective season). The campaign involved a series of light weight payloads, including Pico-SDLA laser spectrometers (H2O, CO2 or CH4), a FLASH Lyman alpha hygrometer, a mini-SOAZ spectrometer for O3, NO2, H2O, COBALD and LOAC aerosol instruments, combined with ground based S-Band radar and an optical depth sensor so-called ODS, satellite observations from CALIPSO, MLS, and adequate modelling tools that is of all parameters sensitive to convective intensity. TRO-pico included a two time-scale campaign with a total of 37 balloon flights including 34 flights using H2O sensors in the flight train: i) a Six Month Observation Period (SMOP) covering to the full wet season

  13. Satellite mission Aeronomy of Ice in the Mesosphere (AIM) partners with formal and informal education programs to study clouds on the edge of space

    NASA Astrophysics Data System (ADS)

    Robinson, D. Q.; Maggi, B. H.

    2004-12-01

    The satellite-based research mission "Aeronomy of Ice In the Mesosphere" (AIM), has developed an exciting partnership of formal and informal education programs that will connect students and the public to the unique scientific aspects of the mission. The AIM satellite mission is dedicated to providing a scientific basis for understanding why Polar Mesospheric Clouds (PMCs) form and vary. PMCs are sometimes known as Noctilucent Clouds (NLCs) or "night shinning" clouds because of their visibility at dawn and dusk. The visible manifestation of PMCs provides a unique opportunity for Education and Public Outreach. The AIM outreach programs will utilize the beautiful images of "clouds on the edge of space" as a tool to motivate students and the public to increase their knowledge and understanding about issues surrounding changes in our atmosphere. In an effort to provide formal and informal outreach opportunities worldwide, AIM has developed a partnership with the GLOBE program. GLOBE is a network of schools, science centers, and clubs from over 105 countries where participants collect scientific data according to precise protocols and enter the data into a central database allowing both scientists and students to utilize the data. The collaboration between AIM and GLOBE will involve participants in collecting and utilizing NLC data worldwide. This partnership will provide a mechanism for sustaining AIM education opportunities for both formal and informal education venues in the future. Included in the formal education component of AIM outreach is the implementation of two educator workshops that will establish partnerships between the mission and classrooms nationwide. The educator workshops will be held in Alaska due to the optimal location for viewing NLCs. Participants attending the workshops will be chosen from a national pool allowing teachers working with students in southern latitudes an opportunity to experience the excitement of working with data that can only

  14. Study objectives: Will commercial avionics do the job? Improvements needed?

    NASA Technical Reports Server (NTRS)

    Nasr, Hatem

    1992-01-01

    Improvements in commercial avionics are covered in a viewgraph format. Topics include the following: computer architecture, user requirements, Boeing 777 aircraft, cost effectiveness, and implemention.

  15. Objectively determined habitual physical activity in South African adolescents: the PAHL study

    PubMed Central

    2014-01-01

    Background There is limited data on objectively determined habitual physical activity (PA) in 16-year old South African adolescents. The purpose of this study was to objectively determine the habitual PA of adolescents from the North West Province of South Africa by race and gender. Methods Adolescents (137 girls, 89 boys) from the ongoing Physical Activity and Health Longitudinal Study (PAHL study), participated in the present study. Habitual PA was objectively recorded by means of the Actiheart® over a period of 7 days. Time spent in moderate-to-vigorous intensity physical activity (MVPA) was assessed. Results Average MVPA for the study sample was 50.9 ± 40.3 minutes/day. Girls were significantly more active than boys expending more time in MVPA (61.13 ± 52.2 minutes/day; p < 0.05) than boys (35.0 ± 32.9 minutes/day). Although white adolescents spent more time in MVPA than black adolescents, there was no significant difference in MVPA between black (47.87 ± 39.6 minutes/day; p = 0.58) and white adolescents (59.5 ± 41.8 minutes/day). Conclusion Physical activity varies by both gender and race in adolescents from the North West Province of South Africa. Objectively determined data from our study indicates that girls habitually spend more time in MVPA per day than boys, and that white adolescents habitually engage in more MVPA than black adolescents. Seeing as the average MVPA per day for the entire study sample falls below the recommended daily average of 60minutes/day, adolescents should be the foremost targets of interventions aimed at enhancing habitual PA. PMID:24885503

  16. Is objective and accurate cognitive assessment across the menstrual cycle possible? A feasibility study

    PubMed Central

    Neill, Jo; Scally, Andy; Tuffnell, Derek; Marshall, Kay

    2015-01-01

    Objectives: Variation in plasma hormone levels influences the neurobiology of brain regions involved in cognition and emotion processing. Fluctuations in hormone levels across the menstrual cycle could therefore alter cognitive performance and wellbeing; reports have provided conflicting results, however. The aim of this study was to assess whether objective assessment of cognitive performance and self-reported wellbeing during the follicular and luteal phases of the menstrual cycle is feasible and investigate the possible reasons for variation in effects previously reported. Methods: The Cambridge Neuropsychological Test Automated Battery and Edinburgh Postnatal Depression Scale were used to assess the cognitive performance and wellbeing of 12 women. Data were analysed by self-reported and hormone-estimated phases of the menstrual cycle. Results: Recruitment to the study and assessment of cognition and wellbeing was without issue. Plasma hormone and peptide estimation showed substantial individual variation and suggests inaccuracy in self-reported menstrual phase estimation. Conclusion: Objective assessment of cognitive performance and self-assessed wellbeing across the menstrual cycle is feasible. Grouping data by hormonal profile rather by self-reported phase estimation may influence phase-mediated results. Future studies should use plasma hormone and peptide profiles to estimate cycle phase and group data for analyses. PMID:26770760

  17. The VicGeneration study - a birth cohort to examine the environmental, behavioural and biological predictors of early childhood caries: background, aims and methods

    PubMed Central

    2010-01-01

    Background Dental caries (decay) during childhood is largely preventable however it remains a significant and costly public health concern, identified as the most prevalent chronic disease of childhood. Caries in children aged less than five years (early childhood caries) is a rapid and progressive disease that can be painful and debilitating, and significantly increases the likelihood of poor child growth, development and social outcomes. Early childhood caries may also result in a substantial social burden on families and significant costs to the public health system. A disproportionate burden of disease is also experienced by disadvantaged populations. Methods/Design This study involves the establishment of a birth cohort in disadvantaged communities in Victoria, Australia. Children will be followed for at least 18 months and the data gathered will explore longitudinal relationships and generate new evidence on the natural history of early childhood caries, the prevalence of the disease and relative contributions of risk and protective biological, environmental and behavioural factors. Specifically, the study aims to: 1. Describe the natural history of early childhood caries (at ages 1, 6, 12 and 18 months), tracking pathways from early bacterial colonisation, through non-cavitated enamel white spot lesions to cavitated lesions extending into dentine. 2. Enumerate oral bacterial species in the saliva of infants and their primary care giver. 3. Identify the strength of concurrent associations between early childhood caries and putative risk and protective factors, including biological (eg microbiota, saliva), environmental (fluoride exposure) and socio-behavioural factors (proximal factors such as: feeding practices and oral hygiene; and distal factors such as parental health behaviours, physical health, coping and broader socio-economic conditions). 4. Quantify the longitudinal relationships between these factors and the development and progression of early

  18. Psychophysiological and physiological aspects of T-wave amplitude in the objective study of behavior.

    PubMed

    Furedy, J J; Heslegrave, R J; Scher, H

    1984-01-01

    The objective study of behavior, which is the stated aim of our society, does not impose restrictions on the levels of explanatory constructs that are used. The only restriction is that the evidence concerning those constructs be stated in an objective or scientifically communicable way. Thus the concepts that we employ to explain behavior range from the sociologic to the biochemical. This article's underlying thesis is that behavior needs to be investigated at various levels, and that these levels should be clearly differentiated in order to bring these investigations into a scientifically meaningful relationship. The thesis is here illustrated by examining evidence and arguments concerning the utility and status of a noninvasive index of myocardial performance: T-wave amplitude (TWA). The examination begins at a psychophysiological-index level, wherein TWA is considered in terms of how well this noninvasive physiological index differentiates psychological processes. Secondly, at a lower physiological-index level, we consider the assumption that TWA reflects a relatively unitary physiological process, myocardial beta-adrenergic sympathetic influence. Both the grounds for and implications of this assumption are discussed. Finally, at the physiological-index level of discourse, brief reference is made to the mechanism by which changes in beta-adrenergic sympathetic innervation may produce correlated changes in TWA. The overall aim of the article is to differentiate these three levels of investigation, and yet also to consider the interrelationship among these three levels in order to provide a fuller scientific understanding of the phenomena involved. PMID:6504582

  19. [The importance of using biological test objects in studying the toxicity of surface-active substances].

    PubMed

    Mudryĭ, I V; Debrivnaia, I E

    1996-01-01

    The Azotobacter agilis [correction of azobacter agile] culture appeared to be the most sensitive one among the studied test objects. Buckwheat as a test plant can be recommended in studying the toxicity of surface-active substances. PMID:9035856

  20. The General Aims of Educational Development -- A Comparative Prospect.

    ERIC Educational Resources Information Center

    Dahawy, Bayoumi Mohamed

    The inconsistency between norms prescribed by international agencies and the educational strategies suggested to put these norms into practice has created problems as is evident in the case studies of India and Egypt and the general aims of educational development in these two countries. In Egypt a policy of basic education had the support of…

  1. [Aiming at the chest, but hitting the back].

    PubMed

    Zech, Wolf-Dieter; Axmann, Stefan; Siegenthaler, Lea; Kneubühl, Beat; Thali, Michael

    2011-01-01

    Gunshot injuries in the back may suggest the unjustified use of firearms. A wound in the back inflicted by a firearm should not automatically imply that the shooter aimed at the back. A previous study demonstrated that it is possible for men to turn their trunk faster than it takes for a shooter to fire or throw a hand-operated weapon. With a high speed motion camera the authors were able to demonstrate that it is also possible for women to turn their trunk fast enough, so that a shot in the back could have been aimed at the front of the body. This conclusion is also likely to apply to hand-operated or thrown weapons, since the velocity of their projectiles is considerably lower than that of firearms. PMID:22039696

  2. A case study evaluation of an intervention aiming to strengthen the midwifery professional role in Morocco: anticipated barriers to reaching outcomes

    PubMed Central

    Abou Malham, Sabina; Hatem, Marie; Leduc, Nicole

    2015-01-01

    Background In order to reduce the high maternal mortality ratio, Morocco is strongly committed to strengthen its midwifery professional role. This study aimed to identify barriers that could potentially hinder an action plan to strengthen the midwifery professional role from achieving desired outcomes. We used a conceptual framework, which is derived from Hatem-Asmar’s (1997) framework on the interaction of educational, professional, and sociocultural systems in which a professional role evolves and from Damschroder et al’s (2009) framework for the implementation analysis. Methods This paper builds on a qualitative case study on the factors affecting the action plan’s implementation process that also revealed rich data about anticipated barriers to reaching outcomes. Data were collected through training sessions, field observations, documents, focus groups (n=20), and semistructured interviews (n=11) with stakeholders pertaining to the three systems under study. Content analysis was used to identify themes related to barriers. Results Seven barriers that may compromise the achievement of desired results were found. They relate to the legal framework, social representations, and media support in the sociocultural system and the practice environment, networks and communication mechanisms, and characteristics related to the role and the readiness in the professional system. Conclusion Disregarding sociocultural and professional system level, barriers may impede efforts to strengthen the midwife’s role and to provide qualified midwives who can improve the quality of maternal care. Making changes in the educational system cannot be thought of as an isolated process. Its success is closely tied with multiple contextual factors pertaining to the two other systems. Activities recommended to address these barriers may have great potential to build a competent midwifery workforce that contributes to positive maternal and neonatal health outcomes. PMID:26445547

  3. Studying the incommensurability that unites us: persuasion across discourse communities, persuasion via boundary objects

    SciTech Connect

    Wilson, G. D.

    2003-01-01

    In the science studies literature the theoretical construct of boundary objects has been developed to explain how diverse communities clustered around a scientific subject area cooperate to advance that area. Boundary objects are 'scientific objects that inhabit several intersecting social worlds . . . and satisfy the informational requirements of each of them' (Star and Griesemer 393). Star and Griesemer's foundational article showed that these objects can be shared by communities ranging from academic researchers to amateur enthiasts, adminsitrators, philanthropists, and technicians. While each community understands the object differently, there is enough commonality in the understanding of the object to unite these distinct social worlds and facilitate cooperation among them.

  4. The neural and cognitive correlates of aimed throwing in chimpanzees: a magnetic resonance image and behavioural study on a unique form of social tool use.

    PubMed

    Hopkins, William D; Russell, Jamie L; Schaeffer, Jennifer A

    2012-01-12

    It has been hypothesized that neurological adaptations associated with evolutionary selection for throwing may have served as a precursor for the emergence of language and speech in early hominins. Although there are reports of individual differences in aimed throwing in wild and captive apes, to date there has not been a single study that has examined the potential neuroanatomical correlates of this very unique tool-use behaviour in non-human primates. In this study, we examined whether differences in the ratio of white (WM) to grey matter (GM) were evident in the homologue to Broca's area as well as the motor-hand area of the precentral gyrus (termed the KNOB) in chimpanzees that reliably throw compared with those that do not. We found that the proportion of WM in Broca's homologue and the KNOB was significantly higher in subjects that reliably throw compared with those that do not. We further found that asymmetries in WM within both brain regions were larger in the hemisphere contralateral to the chimpanzee's preferred throwing hand. We also found that chimpanzees that reliably throw show significantly better communication abilities than chimpanzees that do not. These results suggest that chimpanzees that have learned to throw have developed greater cortical connectivity between primary motor cortex and the Broca's area homologue. It is suggested that during hominin evolution, after the split between the lines leading to chimpanzees and humans, there was intense selection on increased motor skills associated with throwing and that this potentially formed the foundation for left hemisphere specialization associated with language and speech found in modern humans. PMID:22106425

  5. Objectivity and History in the Study of Higher Education: A Note on the Methodology of Research.

    ERIC Educational Resources Information Center

    Hodysh, Henry W.

    1987-01-01

    The pursuit of objectivity is among the most critical yet unresolved problems confronting the study of higher education. The entire process of research is theory-laden, putting into question the possibility of objectivity in historical investigation. A change of approach to address this issue is recommended. (MSE)

  6. Cost-effectiveness analyses of self-harm strategies aimed at reducing the mortality of pesticide self-poisonings in Sri Lanka: a study protocol

    PubMed Central

    Madsen, Lizell Bustamante; Eddleston, Michael; Hansen, Kristian Schultz; Pearson, Melissa; Agampodi, Suneth; Jayamanne, Shaluka; Konradsen, Flemming

    2015-01-01

    Introduction An estimated 803 900 people worldwide died as a result of self-harm in 2012. The deliberate ingestion of pesticides has been identified as the method most frequently used to commit fatal self-harm globally. In Sri Lanka, it is estimated that up to 60% of all suicides are committed using this method. The aim of the present study is to assess the cost-effectiveness of an ongoing safe storage intervention currently taking place in a rural Sri Lankan district and to model the cost-effectiveness of implementing the safe storage intervention as well as four potential interventions (legislative, medical management, follow-up contact and mobile phone contact) on a national level. Methods and analysis Study design for all the strategies is a cost-effectiveness analysis. A governmental perspective is adopted. The time horizon for tracking the associated costs and health outcomes of the safe storage intervention on district level runs over 3 years. The time horizon is extended to 5 years when modelling a full national roll-out of the respective interventions. The discounting of costs and health outcomes are undertaken at the recommended real rate of 3%. Threshold analyses of the modelled strategies are employed to assess the strategies potential for cost-effectiveness, running scenarios with health outcome improvements ranging from 1% to 100%. Sensitivity analyses are also performed. The main outcome measures of the safe storage intervention are incremental cost-effectiveness ratios. Ethics and dissemination Ethical approval was granted for the safe storage project from the University of Peradeniya, Sri Lanka, in March of 2008. An amendment for the present study was granted from Rajarata University of Sri Lanka in November of 2013. Findings will be disseminated to public and private stakeholders in local and national government in Sri Lanka as well as the wider academic audience through peer-reviewed publications and international conferences. Trial

  7. A Discussion of Research Aims and Strategies for Studying Education in the Inner-City (A Critique of Non-Participant Observations). Preliminary Draft.

    ERIC Educational Resources Information Center

    Talbert, Carol

    The objective of naturalistic observations conducted in schools and homes in the inner city was to relate teacher expectation to pupil behavior. Following kindergarten observations, selected black children predicted as potentially successful and black children predicted as poor achievers were observed in their homes along with their mothers. This…

  8. The Early Development of Object Knowledge: A Study of Infants' Visual Anticipations during Action Observation

    ERIC Educational Resources Information Center

    Hunnius, Sabine; Bekkering, Harold

    2010-01-01

    This study examined the developing object knowledge of infants through their visual anticipation of action targets during action observation. Infants (6, 8, 12, 14, and 16 months) and adults watched short movies of a person using 3 different everyday objects. Participants were presented with objects being brought either to a correct or to an…

  9. The Distinctive Features of a Feasibility Study: Objectives and Guiding Questions.

    PubMed

    Orsmond, Gael I; Cohn, Ellen S

    2015-07-01

    In this article, we highlight the distinctive features of a feasibility study, identify the main objectives and guiding questions of a feasibility study, and illustrate the use of these objectives. We synthesized the research methods literature related to feasibility studies to identify five overarching objectives of feasibility studies that focus on social and behavioral interventions. Feasibility studies are designed to answer the overarching question: Can it work? The main objectives of feasibility include the assessment of recruitment capability and resulting sample characteristics, data collection procedures and outcome measures, acceptability of the intervention and study procedures, resources and ability to manage and implement the study and intervention, and preliminary evaluation of participant responses to the intervention. For each objective, we identified follow-up questions designed to assist the researchers to understand barriers to the ultimate success of the research. PMID:26594739

  10. Taking Aims: New CASE Study Benchmarks Advancement Investments and Returns

    ERIC Educational Resources Information Center

    Goldsmith, Rae

    2012-01-01

    Advancement professionals have always been thirsty for information that will help them understand how their programs compare with those of their peers. But in recent years the demand for benchmarking data has exploded as budgets have become leaner, leaders have become more business minded, and terms like "performance metrics and return on…

  11. The Aims of Education and the Leap of Freedom

    ERIC Educational Resources Information Center

    Yun, SunInn

    2014-01-01

    This paper considers the place of freedom in discussions of the aims of education. Bearing in mind remarks of R.S. Peters to the affect that the singling out of aims can "fall into the hands of rationalistically minded curriculum planners", it begins by considering the views of Roland Reichenbach regarding Bildung and his account of this…

  12. Determination of the object surface function by structured light: application to the study of spinal deformities

    NASA Astrophysics Data System (ADS)

    Buendía, M.; Salvador, R.; Cibrián, R.; Laguia, M.; Sotoca, J. M.

    1999-01-01

    The projection of structured light is a technique frequently used to determine the surface shape of an object. In this paper, a new procedure is described that efficiently resolves the correspondence between the knots of the projected grid and those obtained on the object when the projection is made. The method is based on the use of three images of the projected grid. In two of them the grid is projected over a flat surface placed, respectively, before and behind the object; both images are used for calibration. In the third image the grid is projected over the object. It is not reliant on accurate determination of the camera and projector pair relative to the grid and object. Once the method is calibrated, we can obtain the surface function by just analysing the projected grid on the object. The procedure is especially suitable for the study of objects without discontinuities or large depth gradients. It can be employed for determining, in a non-invasive way, the patient's back surface function. Symmetry differences permit a quantitative diagnosis of spinal deformities such as scoliosis.

  13. MonitorNet: the Italian multi-centre observational study aimed at estimating the risk/benefit profile of biologic agents in real-world rheumatology practice.

    PubMed

    Sfriso, P; Salaffi, F; Montecucco, C M; Bombardieri, S; Todesco, S

    2009-01-01

    MonitorNet is a database established by the Italian Society of Rheumatology (SIR) in January 2007 and funded by the Italian Medicines Agency (AIFA), for the active long-term follow-up of patients with rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis treated with biologic agents. All hospital Rheumatology Units in Italy were invited to participate in a non-interventional, observational, epidemiological study. The study is conducted in a routine clinical setting (real-world practice) where biologics are prescribed on the basis of current recommendations. In this report we describe the design, methodology, and present preliminary data of the study. At the time of the analysis (April 2009) the database included 3510 patients: 2469 (70.3%) with established RA, 675 (19.2%) with PsA and 366 (10.4%) with AS. The cumulative follow up period was 8,787 patient-years (RA: 8,388, PsA: 157; AS: 242). There were 1,538 adverse events in 938 (26.7%) patients. Infections were recorded in 630 patients, skin-related adverse events in 142 and post-infusion reactions in 90. A total of 30 malignancies were reported. An interim analysis of efficacy was conducted on 2,148 RA patients. Seven hundred and thirty-one patients (35.8%) achieved EULAR remission (defined as DAS28<2.4). When assessed with the more restrictive CDAI and SDAI criteria, the frequency of remission was lower (17.9% and 14.7% respectively). Availability of funding for this study provided an opportunity to organize a collaborative national network of rheumatology clinics to develop a large multicentre observational study. PMID:19633800

  14. A chicken model for studying the emergence of invariant object recognition

    PubMed Central

    Wood, Samantha M. W.; Wood, Justin N.

    2015-01-01

    “Invariant object recognition” refers to the ability to recognize objects across variation in their appearance on the retina. This ability is central to visual perception, yet its developmental origins are poorly understood. Traditionally, nonhuman primates, rats, and pigeons have been the most commonly used animal models for studying invariant object recognition. Although these animals have many advantages as model systems, they are not well suited for studying the emergence of invariant object recognition in the newborn brain. Here, we argue that newly hatched chicks (Gallus gallus) are an ideal model system for studying the emergence of invariant object recognition. Using an automated controlled-rearing approach, we show that chicks can build a viewpoint-invariant representation of the first object they see in their life. This invariant representation can be built from highly impoverished visual input (three images of an object separated by 15° azimuth rotations) and cannot be accounted for by low-level retina-like or V1-like neuronal representations. These results indicate that newborn neural circuits begin building invariant object representations at the onset of vision and argue for an increased focus on chicks as an animal model for studying invariant object recognition. PMID:25767436

  15. Summary of clinical and laboratory data of study subjects with and without DCE-MRI plaque measurements in the AIM-HIGH clinical trial

    PubMed Central

    O’Brien, Kevin D.; Hippe, Daniel S.; Chen, Huijun; Neradilek, Moni B.; Probstfield, Jeffrey L.; Peck, Suzanne; Isquith, Daniel A.; Canton, Gador; Yuan, Chun; Polissar, Nayak L.; Zhao, Xue-Qiao; Kerwin, William S.

    2016-01-01

    This brief data article summarizes the clinical risk factors and laboratory data of a group of subjects recruited for the AIM-HIGH trial (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides and Impact on Global Health Outcomes) and an associated magnetic resonance imaging (MRI) substudy. The sample is restricted to those on statin therapy at the time of enrollment and data are presented stratified by whether dynamic contrast enhanced MRI (DCE-MRI) markers of carotid plaque vascularity and inflammation were available or not. The data provided herein are directly related to the article “Longer Duration of Statin Therapy is Associated with Decreased Carotid Plaque Vascularity by Magnetic Resonance Imaging” [2]. PMID:26977429

  16. Pursuing the Triple Aim: The First 7 Years

    PubMed Central

    Whittington, John W; Nolan, Kevin; Lewis, Ninon; Torres, Trissa

    2015-01-01

    Context In 2008, researchers at the Institute for Healthcare Improvement (IHI) described the Triple Aim as simultaneously “improving the individual experience of care; improving the health of populations; and reducing the per capita costs of care for populations.” IHI and its close colleagues had determined that both individual and societal changes were needed. Methods In 2007, IHI began recruiting organizations from around the world to participate in a collaborative to implement what became known as the Triple Aim. The 141 participating organizations included health care systems, hospitals, health care insurance companies, and others closely tied to health care. In addition, key groups outside the health care system were represented, such as public health agencies, social services groups, and community coalitions. This collaborative provided a structure for observational research. By noting the contrasts between the contexts and structures of those sites in the collaborative that progressed and those that did not, we were able to develop an ex post theory of what is needed for an organization or community to successfully pursue the Triple Aim. Findings Drawing on our 7 years of experience, we describe the 3 major principles that guided the organizations and communities working on the Triple Aim: creating the right foundation for population management, managing services at scale for the population, and establishing a learning system to drive and sustain the work over time. Conclusions The concept of the Triple Aim is now widely used, because of IHI's work with many organizations and also because of the adoption of the Triple Aim as part of the national strategy for US health care, developed during the implementation of the Patient Protection and Affordable Care Act of 2010. Even those organizations working on the Triple Aim before IHI coined the term found our concept to be useful because it helped them think about all 3 dimensions at once and organize their

  17. A cluster randomized implementation trial to measure the effectiveness of an intervention package aiming to increase the utilization of skilled birth attendants by women for childbirth: study protocol

    PubMed Central

    2014-01-01

    Background Nepal is on track to achieve MDG 5 but there is a huge sub-national disparity with existing high maternal mortality in western and hilly regions. The national priority is to reduce this disparity to achieve the goal at sub-national level. Evidences from developing countries show that increasing utilization of skilled attendant at birth is an important indicator for reducing maternal death. Further, there is a very low utilization during childbirth in western and hilly regions of Nepal which clearly depicts the barriers in utilization of skilled birth attendants. So, there is a need to overcome the identified barriers to increase the utilization thereby decreasing the maternal mortality. The hypothesis of this study is that through a package of interventions the utilization of skilled birth attendants will be increased and hence improve maternal health in Nepal. Method/Design This study involves a cluster randomized controlled trial involving approximately 5000 pregnant women in 36 clusters. The 18 intervention clusters will receive the following interventions: i) mobilization of family support for pregnant women to reach the health facility, ii) availability of emergency funds for institutional childbirth, iii) availability of transport options to reach a health facility for childbirth, iv) training to health workers on communication skills, v) security provisions for SBAs to reach services 24/24 through community mobilization; 18 control clusters will not receive the intervention package. The final evaluation of the intervention is planned to be completed by October 2014. Primary study output of this study is utilization of SBA services. Secondary study outputs measure the uptake of antenatal care, post natal checkup for mother and baby, availability of transportation for childbirth, operation of emergency fund, improved reception of women at health services, and improved physical security of SBAs. Discussion The intervention package is designed to

  18. Conscientious objection, barriers, and abortion in the case of rape: a study among physicians in Brazil.

    PubMed

    Diniz, Debora; Madeiro, Alberto; Rosas, Cristião

    2014-05-01

    In Brazil, to have a legal abortion in the case of rape, the woman's statement that rape has occurred is considered sufficient to guarantee the right to abortion. The aim of this study was to understand the practice and opinions about providing abortion in the case of rape among obstetricians-gynecologists (OBGYNs) in Brazil. A mixed-method study was conducted from April to July 2012 with 1,690 OBGYNs who responded to a structured, electronic, self-completed questionnaire. In the quantitative phase, 81.6% of the physicians required police reports or judicial authorization to guarantee the care requested. In-depth telephone interviews with 50 of these physicians showed that they frequently tested women's rape claim by making them repeat their story to several health professionals; 43.5% of these claimed conscientious objection when they were uncertain whether the woman was telling the truth. The moral environment of illegal abortion alters the purpose of listening to a patient - from providing care to passing judgement on her. The data suggest that women's access to legal abortion is being blocked by these barriers in spite of the law. We recommend that FEBRASGO and the Ministry of Health work together to clarify to physicians that a woman's statement that rape occurred should allow her to access a legal abortion. PMID:24908465

  19. Schooling for Happiness: Rethinking the Aims of Education

    ERIC Educational Resources Information Center

    Cavanagh, Tom

    2008-01-01

    The release of "The New Zealand Curriculum" causes us to rethink the aims of education. Dr Cavanagh offers an alternative set of aims to the vision outlined in the Ministry of Education document, which is based, at least in part, on socialisation into the corporate industrial world. Dr Cavanagh's position is focused on putting relationships at the…

  20. Benchmark integration test for the Advanced Integration Matrix (AIM)

    NASA Astrophysics Data System (ADS)

    Paul, H.; Labuda, L.

    The Advanced Integration Matrix (AIM) studies and solves systems-level integration issues for exploration missions beyond Low Earth Orbit (LEO) through the design and development of a ground-based facility for developing revolutionary integrated systems for joint human-robotic missions. This systems integration approach to addressing human capability barriers will yield validation of advanced concepts and technologies, establish baselines for further development, and help identify opportunities for system-level breakthroughs. Early ground-based testing of mission capability will identify successful system implementations and operations, hidden risks and hazards, unexpected system and operations interactions, mission mass and operational savings, and can evaluate solutions to requirements-driving questions; all of which will enable NASA to develop more effective, lower risk systems and more reliable cost estimates for future missions. This paper describes the first in the series of integration tests proposed for AIM (the Benchmark Test) which will bring in partners and technology, evaluate the study processes of the project, and develop metrics for success.

  1. The Intelligence of Complexity: Do the Ethical Aims of Research and Intervention in Education Not Lead Us to a New Discourse "On the Study Methods of Our Time"?

    ERIC Educational Resources Information Center

    Le Moigne, Jean-Louis

    2013-01-01

    To better appreciate the contribution of the "paradigm of complexity" in Educational sciences, this paper proposes a framework discussing its cultural and historical roots. First, it focuses on Giambattista Vico's (1668-1744) critique of René Descartes' method (1637), contrasting Cartesian's principles (evidence, disjunction, linear…

  2. An Analysis of Aims and the Educational "Event"

    ERIC Educational Resources Information Center

    den Heyer, Kent

    2015-01-01

    In this article, the author explores key distinctions relevant to aims talk in education. He argues that present formulations of aims fail to adequately capture or speak to several overlapping domains involved in schooling: qualification, socialization, and the educational in the form of subjectification (Biesta, 2010). Drawing off Egan and Biesta…

  3. Patriotism, History and the Legitimate Aims of American Education

    ERIC Educational Resources Information Center

    Merry, Michael S.

    2009-01-01

    This article argues that while an attachment to one's country is both natural and even partially justifiable, cultivating loyal patriotism in schools is untenable insofar as it conflicts with the legitimate aims of education. These aims include the epistemological competence necessary for ascertaining important truths germane to the various…

  4. Laugh and Smile upon the Holy Quran: The Study of Analytical Objectivities

    ERIC Educational Resources Information Center

    al-Domi, Mohammad Mahmoud

    2015-01-01

    This study aims to examine the positive impact of The Holy Quran based on the laugh and smile. This kind of derivatives in which context of praise, expression the feeling of happiness and joyful in the positive senses. Everyone needs to relieve his heart so that happiness and joy on their faces can be seen. Laughter also are some of attribute…

  5. 'A dispassionate and objective effort:' negotiating the first study on the Biological Effects of Atomic Radiation.

    PubMed

    Hamblin, Jacob Darwin

    2007-01-01

    The National Academy of Science's 1956 study on the Biological Effects of Atomic Radiation (BEAR) was designed to provide an objective analysis to assess conflicting statements by leading geneticists and by officials in the Atomic Energy Commission. Largely because of its status as a detached, non-governmental evaluation by eminent scientists, no studies have had a broader impact on the development of biological thinking in regard to nuclear policies. This paper demonstrates that despite the first BEAR study's reputation as an objective and independent study, it was the product of careful negotiation between Academy scientists, the Atomic Energy Commission, and Britain's Medical Research Council. This paper also reveals the fragility of the consensus that produced the Academy's report, the range of political uses of the report, and the subsequent disaffection of the scientists who took part in it. PMID:17993170

  6. An Empirical Study of Block Matching Techniques for the Detection of Moving Objects

    SciTech Connect

    Love, N S; Kamath, C

    2006-01-09

    The basis of surveillance, event detection, and tracking applications is the detection of moving objects in complex scenes. Complex scenes are difficult to analyze because of camera noise and lighting conditions. Currently, moving objects are detected primarily using background subtraction. We analyze block matching as an alternative for detecting moving objects. Block matching has been extensively utilized in compression algorithms for motion estimation. Besides detection of moving objects, block matching also provides motion vectors (location of motion) which can aide in tracking objects. Block matching techniques consist of three main components: block determination, search methods, and matching criteria. We compare various options for each of the components with moving object detection as the performance goal. Publicly available sequences of several different traffic and weather conditions are used to evaluate the techniques. A coherence metric and the average magnitude of object motion vector error are used to evaluate block determination approaches and search methods. To compare the matching criteria we use precision-recall curves to evaluate the performance of motion detection. We present an empirical study of the block matching techniques using these metrics of performance as well as process timing. We found the hierarchical block determination approach has an overall higher coherence of object motion vectors than the simple block determination approach, but with a significant increase in process timing. The average magnitude of object motion vector for the search methods evaluated were comparable, with the cross search method having a better coherence of object motion vectors. Overall the three step search (TSS) detects more moving objects than the cross and 2D-logarithmic search methods. And the mean square difference (MSD) matching criterion has the best precision-recall as well as process timing when using zero motion biasing.

  7. The Florida State Twin Registry: research aims and design.

    PubMed

    Taylor, Jeanette E; James, Lisa M; Reeves, Mark D; Bobadilla, Leonardo

    2006-12-01

    Relatively little is known about the relationship of most personality disorders to executive cognitive functioning despite their associations with frontal cortex activity. Research on genetic influence is lacking for most personality disorders, and research on genetic influences associated with executive cognitive functioning is sparse and mixed. The Florida State Twin Registry was created to conduct a pilot twin study aimed at examining genetic influence on personality disorders and executive cognitive functioning. Measures included structured clinical interviews for symptoms and diagnoses of personality disorders (borderline, histrionic, narcissistic, antisocial, obsessive-compulsive, avoidant, and dependent), depression, substance abuse/dependence, anxiety disorders, and eating disorders. The Wisconsin Card Sorting Test and the Stroop Color-Word Test were administered to assess executive cognitive functioning. Self-report questionnaires were included to assess maladaptive personality traits. Data sharing and future directions for growing the Florida State Twin Registry are discussed. PMID:17254436

  8. What Should Religious Education in Germany Be about and How Does Religiosity Fit into This Picture? An Empirical Study of Pre-Service Religious Education Teachers' Beliefs on the Aims of RE

    ERIC Educational Resources Information Center

    Riegel, Ulrich; Mendl, Hans

    2014-01-01

    In secularising Germany the aim of religious education (RE) is under discussion. The churches opt for denominational education familiarising the students with their own religious tradition. Humanists claim an ethical education, giving students objective information about different religions. Which perspective do students who will become RE…

  9. Examining the Minimal Required Elements of a Computer-Tailored Intervention Aimed at Dietary Fat Reduction: Results of a Randomized Controlled Dismantling Study

    ERIC Educational Resources Information Center

    Kroeze, Willemieke; Oenema, Anke; Dagnelie, Pieter C.; Brug, Johannes

    2008-01-01

    This study investigated the minimally required feedback elements of a computer-tailored dietary fat reduction intervention to be effective in improving fat intake. In all 588 Healthy Dutch adults were randomly allocated to one of four conditions in an randomized controlled trial: (i) feedback on dietary fat intake [personal feedback (P feedback)],…

  10. Objective Subsurface Geological Modeling using Geological Columns - A case study for the Kisarazu Distinct, Japan

    NASA Astrophysics Data System (ADS)

    Nonogaki, S.; Nakazawa, T.

    2013-12-01

    Geological models of subsurface structure play an important role in disaster assessment, environmental preservation, and underground utilization. These models are often constructed subjectively based on geological data obtained from field survey. However, reliability of subjective model depends on modeler's knowledge and experience as well as on quality of basic data. In order to ensure a more stable reliability of the model, objective approach is necessary. The purpose of this study is to establish an objective geological modeling method. For the purpose of this study, we constructed a subsurface geological model focusing on mathematical treatment of stratigraphy. Study area is the Kisarazu distinct, in the middle part of Chiba Prefecture, Japan. Basic data for modeling are 44 geological columns. In the modeling, firstly, we constructed a Logical Model of Geological Structure (LMGS) that defines a positional relation between geological boundary surfaces and geological units. The LMGS is objectively given by recurrence formula derived from a sequence of geological events arranged in chronological order. Secondly, we generated Digital Elevation Models (DEMs) of geological boundary surfaces using geological columns. Thirdly, we constructed an objective geological model using the LMGS and the DEMs. Finally, we visualized the model in 2D and 3D using GRASS GIS. As a result, in the areas with high number of geological columns, geological map and geological cross-sections derived from objective model were in good agreement with the ones derived from subjective model reported in other studies. In the areas with low number of geological columns, the objective map and cross-sections were somewhat different from subjective ones. In conclusion, the results indicate that objective model may give new findings about subsurface structure. In addition, the objective model gives a more stable reliability than the subjective model because the former ensures traceability of modeling

  11. Mechanistic and synthetic studies aimed at the development of single-site metal alkoxide catalysts for the generation of polyesters and polycarbonates

    SciTech Connect

    Chisholm, Malcolm

    2010-06-30

    The work proposed herein focuses on the chemistry of metal-oxygen bonds with respect to insertion/enchainment reactions involving epoxides, cyclic esters and carbonates, acid anhydrides and carbon dioxide leading to the formation of polyethers, polyesters and polycarbonates from renewable resources. Particular emphasis is placed on the use of the biologically benign metals magnesium and calcium and the M(3+) ions of aluminum, chromium and cobalt that have a similar ionic radii but different coordination properties arising from their respective d0, d3 and d6 valence shell configurations. The work emphasizes the design and use of single-site metal catalysis involving LMOR initiating and propagating species. For M = Mg and Ca, L is a pyrazolyl borate ligand specifically tailored to the coordination properties of the metal. In addition the ligand is inert with respect to reactions of the substrates under consideration. For the M(3+) ions, L is a substituted porphyrin, namely 5,10,15,20-tetraphenylporphyrin, TPP, 5,10,15,20-tetrakis(pentafluorophenyl)porphyrin, TFPP or 2,3,7,8,12,13,17,18-octaethylporphyrin, which together with Lewis base co-catalysts will allow the elucidation of factors leading to polyethers, polycarbonates and cyclic carbonates in reactions involving epoxides and CO2. Specific attention is given to reactions involving propylene oxide and styrene oxide which commonly show competitive formation of products. Electronic structure calculations employing Density Functional Theory will be carried out to elucidate the ring opening of the epoxide by alkylcarbonate and alkoxide ligands and the chain growth mechanism. Polymerization of lactide will be investigated using inexpensive solid supports and catalytic routes to cyclic esters are proposed wherein complexation to metal ions may allow chemical amplification of specific rings. With an understanding of mechanisms involving the reactions of M-OR bonds the development of single-site catalysis for the

  12. Ecological studies of disturbed landscapes: a compendium of the results of five years of research aimed at the restoration of disturbed ecosystems

    SciTech Connect

    Dvorak, A.J.

    1984-09-01

    Results of a research program which investigates some of the fundamental environmental questions associated with coal extraction as part of DOE's broad mission to understand the environmental consequences of energy development are described. This document summarizes that program. The report is divided into 12 chapters which cover topics including revegetation of disturbed land in arid ecosystems; microbial ecology and nutrient cycling; amelioration of acid waste materials; effects of mining on watershed hydrology and water quality; etc. Each chapter has been separately indexed and is included in the EDB. (MDF)

  13. Mechanical objects and the engineering learner: An experimental study of how the presence of objects affects students' performance on engineering related tasks

    NASA Astrophysics Data System (ADS)

    Bairaktarova, Diana N.

    People display varying levels of interaction with the mechanical objects in their environment; engineers in particular as makers and users of these objects display a higher level of interaction with them. Investigating the educational potential of mechanical objects in stimulating and supporting learning in engineering is warranted by the fact that practicing engineers work with mechanical objects as they design, test and improve devices. It is possible that mechanical objects can facilitate learning by providing opportunities to authenticate the teaching and learning experience. More importantly, mechanical objects can serve as an instrument in transferring the knowledge of abstract concepts to practical applications. What remains unclear is how individual differences in interests and aptitudes are related to these interactions in engineering students. This study investigated how individual differences related to thing orientation and mechanical aptitude affect interaction with mechanical objects in engineering education instruction. The study introduces a task designed to replicate a real-world engineering application and uses this task to examine the effect of these aptitudes, interests, and direct manipulation of mechanical objects on performance.

  14. Provider Burnout and Patient Engagement: The Quadruple and Quintuple Aims.

    PubMed

    Epperson, William Jackson; Childs, Susan Fink; Wilhoit, Gordon

    2016-01-01

    The Triple Aim has become the guiding light and benchmark by which healthcare organizations plan their future efforts. It has been adopted into healthcare policies with little regard for including the skill sets of compassion and emotional intelligence. The multiple increasing demands on providers of healthcare are unsustainable and will cripple the system, resulting in outcomes that are counter to the Triple Aim goals. Patient engagement with shared decision-making should become the primary focus of care delivery. New delivery models and care plans are unaffordable to far too many patients and payers, despite the efforts of futurists who seek to advance quality and lower costs. Clinical care delivery and patient engagement efforts must be drastically redirected to innovative and sustainable value-based delivery models that support the goals of the Triple Aim. PMID:27443059

  15. Rats' Visual-Spatial Working Memory: New Object Choice Accuracy as a Function of Number of Objects in the Study Array

    ERIC Educational Resources Information Center

    Cohen, Jerome; Han, Xue; Matei, Anca; Parameswaran, Varakini; Zuniga, Robert; Hlynka, Myron

    2010-01-01

    When rats had to find new (jackpot) objects for rewards from among previously sampled baited objects, increasing the number of objects in the sample (study) segment of a trial from 3 to 5 and then to 7 (Experiment 1) or from 3 to 6 and 9 (Experiments 2 and 3) or from 6 to 9 and 12 (Experiment 4) did not reduce rats' test segment performance.…

  16. MayDay Colloquium 24: The Aims of Music Education

    ERIC Educational Resources Information Center

    Elliott, David J.

    2013-01-01

    On June 20, 2012, Professor John Kratus welcomed the MayDay Group to Michigan State University for "Colloquium 24: The Aims of Music Education". On behalf of all members of the Mayday Group, the author wishes to extend his deepest gratitude to Professor Kratus and his colleagues at Michigan State for their extremely gracious and…

  17. Comment on "Schooling for Happiness: Rethinking the Aims of Education"

    ERIC Educational Resources Information Center

    Glynn, Ted

    2008-01-01

    This commentary presents the author's response to an article published in the last version of "Kairaranga" entitled "Schooling for Happiness: Rethinking the aims of education," written by Dr. Tom Cavanagh. He found it refreshing to read Cavanagh's article that focuses educators' energies onto re-visiting the wider socio-cultural goals of…

  18. Alienation, Art and Affirmation in the Work of Aime Cesaire.

    ERIC Educational Resources Information Center

    Buzash, Michael D.

    Aime Cesaire is one of the foremost French-speaking blacks in twentieth century literature. The concept of negritude--referring to the culture of French-speaking blacks--is often associated with his name. This paper discusses his life and work, and explores his life from his birth in Martinique, his early years, the years spent in Paris, and his…

  19. Autonomy as the Guiding Aim of Entrepreneurship Education

    ERIC Educational Resources Information Center

    van Gelderen, Marco

    2010-01-01

    Purpose: This paper has three purposes: first, to present a vision of entrepreneurship education that has the student's capacity for autonomous action as its ultimate aim; second, to convince the reader of the timeliness and relevance of such an approach; third, to outline how this can be implemented. Design/methodology/approach: The paper…

  20. Why the Aims of Education Cannot Be Settled

    ERIC Educational Resources Information Center

    Hardarson, Atli

    2012-01-01

    The dominant model of curriculum design in the last century assumed that school education could be organized around aims, defined primarily in terms of students' behaviour. The credentials of this model were questioned by, among others, Lawrence Stenhouse, who pointed out that education serves purposes that cannot be stated in terms of behavioural…

  1. Clinical Factors Associated with High-risk Carotid Plaque Features as Assessed by Magnetic Resonance Imaging in Patients with Established Vascular Disease (From the AIM-HIGH Study)

    PubMed Central

    Zhao, Xue-Qiao; Hatsukami, Thomas S.; Hippe, Daniel S.; Sun, Jie; Balu, Niranjan; Isquith, Daniel A.; Crouse, John R.; Anderson, Todd; Huston, John; Polissar, Nayak; O’Brien, Kevin; Yuan, Chun

    2014-01-01

    Association between clinical factors and high-risk plaque features such as thin or ruptured cap, intra-plaque hemorrhage (IPH), presence of Lipid Rich Necrotic Core (LRNC) and increased LRNC volume as assessed by Magnetic Resonance Imaging (MRI) was examined in patients with established vascular disease in AIM-HIGH. A total of 214 subjects underwent carotid MRI and had acceptable image quality for assessment of plaque burden, tissue contents and MRI-modified AHA lesion type by a Core Lab. We found that 77% of subjects had carotid plaques, 52% had lipid-containing plaques, and 11% had advanced, AHA type-VI lesions with possible surface defect, IPH or mural thrombus. Type-VI lesions were associated with older age (OR=2.6 per 5 years increase, p<0.001). After adjusting for age, these lesions were associated with history of cerebrovascular disease (OR=4.1, p=0.01), higher levels of Lipoprotein(a) (OR=2.0 per 1 SD increase, p=0.02) and larger %wall volume (%WV; OR=4.6 per 1 SD increase, p<0.001), but, were negatively associated with metabolic syndrome (OR=0.2, p=0.02). Presence of LRNC was associated with male gender (OR=3.2, p=0.02) and %WV (OR=3.8 per 1 SD, p<0.001), but, was negatively associated with diabetes (OR=0.4, p=0.02) and HDL-C levels (OR=0.7 per 1 SD, p=0.02). Increased %LRNC was associated with %WV (regression coefficient=0.36, p<0.001) and negatively associated with ApoA1 levels (regression coefficient=−0.20, p=0.03). In conclusions, older age, male gender, history of cerebrovascular disease, larger plaque burden, higher Lp(a), and lower HDL-C or ApoA1 have statistically significant associations with high-risk plaque features. Metabolic syndrome and diabetes showed negative associations in this population. PMID:25245415

  2. AN OBJECTIVE ANALYSIS TECHNIQUE FOR THE REGIONAL AIR POLLUTION STUDY. PART I

    EPA Science Inventory

    This report documents the development of an objective analysis program for the mesoscale gridding of wind and temperature for the Regional Air Pollution Study being conducted in St. Louis by the Environmental Protection Agency. The program is designed to produce a 5-km spaced hor...

  3. The Development of Object Function and Manipulation Knowledge: Evidence from a Semantic Priming Study.

    PubMed

    Collette, Cynthia; Bonnotte, Isabelle; Jacquemont, Charlotte; Kalénine, Solène; Bartolo, Angela

    2016-01-01

    Object semantics include object function and manipulation knowledge. Function knowledge refers to the goal attainable by using an object (e.g., the function of a key is to open or close a door) while manipulation knowledge refers to gestures one has to execute to use an object appropriately (e.g., a key is held between the thumb and the index, inserted into the door lock and then turned). To date, several studies have assessed function and manipulation knowledge in brain lesion patients as well as in healthy adult populations. In patients with left brain damage, a double dissociation between these two types of knowledge has been reported; on the other hand, behavioral studies in healthy adults show that function knowledge is processed faster than manipulation knowledge. Empirical evidence has shown that object interaction in children differs from that in adults, suggesting that the access to function and manipulation knowledge in children might also differ. To investigate the development of object function and manipulation knowledge, 51 typically developing 8-9-10 year-old children and 17 healthy young adults were tested on a naming task associated with a semantic priming paradigm (190-ms SOA; prime duration: 90 ms) in which a series of line drawings of manipulable objects were used. Target objects could be preceded by three priming contexts: related (e.g., knife-scissors for function; key-screwdriver for manipulation), unrelated but visually similar (e.g., glasses-scissors; baseball bat-screwdriver), and purely unrelated (e.g., die-scissors; tissue-screwdriver). Results showed a different developmental pattern of function and manipulation priming effects. Function priming effects were not present in children and emerged only in adults, with faster naming responses for targets preceded by objects sharing the same function. In contrast, manipulation priming effects were already present in 8-year-olds with faster naming responses for targets preceded by objects

  4. The Development of Object Function and Manipulation Knowledge: Evidence from a Semantic Priming Study

    PubMed Central

    Collette, Cynthia; Bonnotte, Isabelle; Jacquemont, Charlotte; Kalénine, Solène; Bartolo, Angela

    2016-01-01

    Object semantics include object function and manipulation knowledge. Function knowledge refers to the goal attainable by using an object (e.g., the function of a key is to open or close a door) while manipulation knowledge refers to gestures one has to execute to use an object appropriately (e.g., a key is held between the thumb and the index, inserted into the door lock and then turned). To date, several studies have assessed function and manipulation knowledge in brain lesion patients as well as in healthy adult populations. In patients with left brain damage, a double dissociation between these two types of knowledge has been reported; on the other hand, behavioral studies in healthy adults show that function knowledge is processed faster than manipulation knowledge. Empirical evidence has shown that object interaction in children differs from that in adults, suggesting that the access to function and manipulation knowledge in children might also differ. To investigate the development of object function and manipulation knowledge, 51 typically developing 8-9-10 year-old children and 17 healthy young adults were tested on a naming task associated with a semantic priming paradigm (190-ms SOA; prime duration: 90 ms) in which a series of line drawings of manipulable objects were used. Target objects could be preceded by three priming contexts: related (e.g., knife-scissors for function; key-screwdriver for manipulation), unrelated but visually similar (e.g., glasses-scissors; baseball bat-screwdriver), and purely unrelated (e.g., die-scissors; tissue-screwdriver). Results showed a different developmental pattern of function and manipulation priming effects. Function priming effects were not present in children and emerged only in adults, with faster naming responses for targets preceded by objects sharing the same function. In contrast, manipulation priming effects were already present in 8-year-olds with faster naming responses for targets preceded by objects

  5. The Aims of Sex Education: Demoting Autonomy and Promoting Mutuality

    ERIC Educational Resources Information Center

    McAvoy, Paula

    2013-01-01

    In this essay, Paula McAvoy critiques a commonly held view that teaching young people to be good choice makers should be a central aim of sex education. Specifically, she argues against David Archard's recommendation that sex educators ought to focus on the development of autonomy and teaching young people that "choice should be accorded…

  6. Spontaneous object recognition: a promising approach to the comparative study of memory

    PubMed Central

    Blaser, Rachel; Heyser, Charles

    2015-01-01

    Spontaneous recognition of a novel object is a popular measure of exploratory behavior, perception and recognition memory in rodent models. Because of its relative simplicity and speed of testing, the variety of stimuli that can be used, and its ecological validity across species, it is also an attractive task for comparative research. To date, variants of this test have been used with vertebrate and invertebrate species, but the methods have seldom been sufficiently standardized to allow cross-species comparison. Here, we review the methods necessary for the study of novel object recognition in mammalian and non-mammalian models, as well as the results of these experiments. Critical to the use of this test is an understanding of the organism’s initial response to a novel object, the modulation of exploration by context, and species differences in object perception and exploratory behaviors. We argue that with appropriate consideration of species differences in perception, object affordances, and natural exploratory behaviors, the spontaneous object recognition test can be a valid and versatile tool for translational research with non-mammalian models. PMID:26217207

  7. Inverting the Object of Study: Recalibrating the Frame of Reference in Study Abroad Experiences

    ERIC Educational Resources Information Center

    Palmer, Norris W.

    2015-01-01

    This essay is concerned with study abroad experiences as opportunities for student cognitive development, using the interpretive lens of educational psychologist William G. Perry. A standard and often valuable assignment in courses on world religions is a site visit to a religious institution in one's local area. This may concretize otherwise…

  8. Rethinking Trends in Instructional Objectives: Exploring the Alignment of Objectives with Activities and Assessment in Higher Education--A Case Study

    ERIC Educational Resources Information Center

    Yamanaka, Akio; Wu, Leon Yufeng

    2014-01-01

    This study explored higher education level syllabi to identify trends in educational objectives. Bloom's Taxonomy and various strategic models were used to classify 714 objectives from 114 sections of courses administered through a Midwest teacher education institution in the United States. 1229 verbs and verb phrases were classified through the…

  9. A method for real-time visual stimulus selection in the study of cortical object perception.

    PubMed

    Leeds, Daniel D; Tarr, Michael J

    2016-06-01

    The properties utilized by visual object perception in the mid- and high-level ventral visual pathway are poorly understood. To better establish and explore possible models of these properties, we adopt a data-driven approach in which we repeatedly interrogate neural units using functional Magnetic Resonance Imaging (fMRI) to establish each unit's image selectivity. This approach to imaging necessitates a search through a broad space of stimulus properties using a limited number of samples. To more quickly identify the complex visual features underlying human cortical object perception, we implemented a new functional magnetic resonance imaging protocol in which visual stimuli are selected in real-time based on BOLD responses to recently shown images. Two variations of this protocol were developed, one relying on natural object stimuli and a second based on synthetic object stimuli, both embedded in feature spaces based on the complex visual properties of the objects. During fMRI scanning, we continuously controlled stimulus selection in the context of a real-time search through these image spaces in order to maximize neural responses across pre-determined 1cm(3) rain regions. Elsewhere we have reported the patterns of cortical selectivity revealed by this approach (Leeds et al., 2014). In contrast, here our objective is to present more detailed methods and explore the technical and biological factors influencing the behavior of our real-time stimulus search. We observe that: 1) Searches converged more reliably when exploring a more precisely parameterized space of synthetic objects; 2) real-time estimation of cortical responses to stimuli is reasonably consistent; 3) search behavior was acceptably robust to delays in stimulus displays and subject motion effects. Overall, our results indicate that real-time fMRI methods may provide a valuable platform for continuing study of localized neural selectivity, both for visual object representation and beyond. PMID

  10. AN OBJECTIVE ANALYSIS TECHNIQUE FOR THE REGIONAL AIR POLLUTION STUDY. PART II

    EPA Science Inventory

    This report discusses the application of objective analysis techniques to the computation of trajectories from surface wind observations of the Regional Air Pollution Study in St. Louis. Trajectories were computed over a 100-kilometer square grid centered on St. Louis for two 5-h...

  11. The Study of Object-Oriented Motor Imagery Based on EEG Suppression

    PubMed Central

    Li, Lili; Wang, Jing; Xu, Guanghua; Li, Min; Xie, Jun

    2015-01-01

    Motor imagery is a conventional method for brain computer interface and motor learning. To avoid the great individual difference of the motor imagery ability, object-oriented motor imagery was applied, and the effects were studied. Kinesthetic motor imagery and visual observation were administered to 15 healthy volunteers. The EEG during cue-based simple imagery (SI), object-oriented motor imagery (OI), non-object-oriented motor imagery (NI) and visual observation (VO) was recorded. Study results showed that OI and NI presented significant contralateral suppression in mu rhythm (p < 0.05). Besides, OI exhibited significant contralateral suppression in beta rhythm (p < 0.05). While no significant mu or beta contralateral suppression could be found during VO or SI (p > 0.05). Compared with NI, OI showed significant difference (p < 0.05) in mu rhythm and weak significant difference (p = 0.0612) in beta rhythm over the contralateral hemisphere. The ability of motor imagery can be reflected by the suppression degree of mu and beta frequencies which are the motor related rhythms. Thus, greater enhancement of activation in mirror neuron system is involved in response to object-oriented motor imagery. The object-oriented motor imagery is favorable for improvement of motor imagery ability. PMID:26641241

  12. Aiming for Positive Washback: A Case Study of International Teaching Assistants

    ERIC Educational Resources Information Center

    Saif, Shahrzad

    2006-01-01

    The aim of this study is to explore the possibility of creating positive washback by focusing on factors in the background of the test development process and anticipating the conditions most likely to lead to positive wash-back. The article reports on a multiphase empirical study investigating the washback effects of a needs-based test of spoken…

  13. Non-destructive analysis in a study of the religious art objects

    NASA Astrophysics Data System (ADS)

    Vornicu, Nicoleta; Geba, Maria; Bibire, Cristina

    2009-08-01

    The icon Descending of the Saint Spirit from Bucium Church, dating in the year 1814 and was done in tempera on wood technology. The characterization of cultural heritage materials is essential for the comprehension of their degradation mechanisms. The present study aims at identifying the pigments in the various layers, establishing the possible existence of an organic binder and scientifically evaluating the state of preservation. To this end, were used non-destructive methods, as: microscopic (SEM), XRF and spectroscopic (FTIR).

  14. Use of the argon aiming beam in visual function testing.

    PubMed

    Kelley, J S

    1978-12-01

    The aiming beam of the argon laser photocoagulator can be a useful tool in visual function testing. Applied with the slit lamp delivery system and fundus contact lens, it clearly documents the size of the blind spot surrounding the optic nerve head and the normal area of nonfunctional retina in the periphery. The size of pathologic field defects can be recorded on fundus photographs or retinal drawings by an observer. Safety precautions must be taken to protect all patients from excessive laser energy. PMID:736394

  15. A New Spectroscopic and Interferometric Study of the Young Stellar Object V645 Cyg

    NASA Technical Reports Server (NTRS)

    Miroshinichenko, A. S.; Hofmann, K.-H.; Schertl, D.; Weigelt, G.; Kraus, S.; Manset, N.; Balega, Y. Y.; Klochkova, V. G.; Rudy, R. J.; Lynch, D. K.; Mazuk, S.; Venturini, C. C.; Grankin, K. N.; Puetter, R. C.; Perry, R. B.

    2009-01-01

    Aims. We present the results of high-resolution optical spectroscopy, low-resolution near-IR spectroscopy and near-infrared speckle interferometry of the massive young stellar object candidate V645 Cyg that were taken in order to refine its fundamental parameters and properties of its circumstellar envelope. Methods. Speckle interferometry in the H- and K-bands and an optical spectrum in the range 5200-6680 A with a spectral resolving power of R = 60000 were obtained at the 6 m telescope of the Russian Academy of Sciences. Another optical spectrum in the range 4300-10500 A with R = 79000 was obtained at the 3.6m CFHT. A low-resolution spectrum in the ranges 0.46-1.4 and 1.4-2.5 microns with a R approx. 800 and approx. 700, respectively, were obtained at the 3m Shain telescope of the Lick Observatory. Results. Using a new kinematic method based on non-linear modeling of the neutral hydrogen density profile in the direction toward the object, we suggest a new a distance D = 4.2+/-0.2 kpc. We also suggest a new estimate for the star's effective temperature, T(sub eff) approx. 25000 K. We have resolved the object in both H- and K-bands. Using a two-component ring fit, we derived a compact component size of 18 mas and 15 mas in the H- and K-band, respectively, which correspond to 37 and 33 AU at the new distance. Analysis of our and previously published data shows a approx. 2 mag drop of the near-infrared brightness of V645 Cyg in the beginning of the 1980 s. At the same time, the cometary nebular condensation N1 seems to fade in this wavelength range with respect to the N0 object, which represent the star with a nearly pole-on optically-thick disk and an optically-thin envelope. Conclusions. We conclude that V645 Cyg is a young massive main-sequence star, which recently emerged from its cocoon. and already passed the protostellar accretion stage. The presence of accretion is not necessary to account for the high observed luminosity of (2.6) x 10(exp 4) Solar Mass

  16. Objective Sleep Structure and Cardiovascular Risk Factors in the General Population: The HypnoLaus Study

    PubMed Central

    Haba-Rubio, José; Marques-Vidal, Pedro; Andries, Daniela; Tobback, Nadia; Preisig, Martin; Vollenweider, Peter; Waeber, Gérard; Luca, Gianina; Tafti, Mehdi; Heinzer, Raphaël

    2015-01-01

    Study Objectives: To evaluate the association between objective sleep measures and metabolic syndrome (MS), hypertension, diabetes, and obesity. Design: Cross-sectional study. Setting: General population sample. Participants: There were 2,162 patients (51.2% women, mean age 58.4 ± 11.1). Interventions: Patients were evaluated for hypertension, diabetes, overweight/obesity, and MS, and underwent a full polysomnography (PSG). Measurements and Results: PSG measured variables included: total sleep time (TST), percentage and time spent in slow wave sleep (SWS) and in rapid eye movement (REM) sleep, sleep efficiency and arousal index (ArI). In univariate analyses, MS was associated with decreased TST, SWS, REM sleep, and sleep efficiency, and increased ArI. After adjustment for age, sex, smoking, alcohol, physical activity, drugs that affect sleep and depression, the ArI remained significantly higher, but the difference disappeared in patients without significant sleep disordered breathing (SDB). Differences in sleep structure were also found according to the presence or absence of hypertension, diabetes, and overweight/obesity in univariate analysis. However, these differences were attenuated after multivariate adjustment and after excluding subjects with significant SDB. Conclusions: In this population-based sample we found significant associations between sleep structure and metabolic syndrome (MS), hypertension, diabetes, and obesity. However, these associations were cancelled after multivariate adjustment. We conclude that normal variations in sleep contribute little if any to MS and associated disorders. Citation: Haba-Rubio J, Marques-Vidal P, Andries D, Tobback N, Preisig M, Vollenweider P, Waeber G, Luca G, Tafti M, Heinzer R. Objective sleep structure and cardiovascular risk factors in the general population: the HypnoLaus study. SLEEP 2015;38(3):391–400. PMID:25325467

  17. The Scope and Aims of the Information Sciences and Technologies.

    ERIC Educational Resources Information Center

    Fairthorne, Robert A.

    This paper studies the composition and scope of the information sciences. These arise, or will arise, from the dependence of the modern world upon records, and therefore upon means to facilitate discourse. Such means range from the physical to the conceptual, but all entail aspects of language, therefore they must all involve social activities,…

  18. A Probabilistic Risk Analysis (PRA) of Human Space Missions for the Advanced Integration Matrix (AIM)

    NASA Technical Reports Server (NTRS)

    Jones, Harry W.; Dillon-Merrill, Robin L.; Thomas, Gretchen A.

    2003-01-01

    The Advanced Integration Matrix (AIM) Project u7ill study and solve systems-level integration issues for exploration missions beyond Low Earth Orbit (LEO), through the design and development of a ground-based facility for developing revolutionary integrated systems for joint human-robotic missions. This paper describes a Probabilistic Risk Analysis (PRA) of human space missions that was developed to help define the direction and priorities for AIM. Risk analysis is required for all major NASA programs and has been used for shuttle, station, and Mars lander programs. It is a prescribed part of early planning and is necessary during concept definition, even before mission scenarios and system designs exist. PRA cm begin when little failure data are available, and be continually updated and refined as detail becomes available. PRA provides a basis for examining tradeoffs among safety, reliability, performance, and cost. The objective of AIM's PRA is to indicate how risk can be managed and future human space missions enabled by the AIM Project. Many critical events can cause injuries and fatalities to the crew without causing loss of vehicle or mission. Some critical systems are beyond AIM's scope, such as propulsion and guidance. Many failure-causing events can be mitigated by conducting operational tests in AIM, such as testing equipment and evaluating operational procedures, especially in the areas of communications and computers, autonomous operations, life support, thermal design, EVA and rover activities, physiological factors including habitation, medical equipment, and food, and multifunctional tools and repairable systems. AIM is well suited to test and demonstrate the habitat, life support, crew operations, and human interface. Because these account for significant crew, systems performance, and science risks, AIM will help reduce mission risk, and missions beyond LEO are far enough in the future that AIM can have significant impact.

  19. The Automated Instrumentation and Monitoring System (AIMS) reference manual

    NASA Technical Reports Server (NTRS)

    Yan, Jerry; Hontalas, Philip; Listgarten, Sherry

    1993-01-01

    Whether a researcher is designing the 'next parallel programming paradigm,' another 'scalable multiprocessor' or investigating resource allocation algorithms for multiprocessors, a facility that enables parallel program execution to be captured and displayed is invaluable. Careful analysis of execution traces can help computer designers and software architects to uncover system behavior and to take advantage of specific application characteristics and hardware features. A software tool kit that facilitates performance evaluation of parallel applications on multiprocessors is described. The Automated Instrumentation and Monitoring System (AIMS) has four major software components: a source code instrumentor which automatically inserts active event recorders into the program's source code before compilation; a run time performance-monitoring library, which collects performance data; a trace file animation and analysis tool kit which reconstructs program execution from the trace file; and a trace post-processor which compensate for data collection overhead. Besides being used as prototype for developing new techniques for instrumenting, monitoring, and visualizing parallel program execution, AIMS is also being incorporated into the run-time environments of various hardware test beds to evaluate their impact on user productivity. Currently, AIMS instrumentors accept FORTRAN and C parallel programs written for Intel's NX operating system on the iPSC family of multi computers. A run-time performance-monitoring library for the iPSC/860 is included in this release. We plan to release monitors for other platforms (such as PVM and TMC's CM-5) in the near future. Performance data collected can be graphically displayed on workstations (e.g. Sun Sparc and SGI) supporting X-Windows (in particular, Xl IR5, Motif 1.1.3).

  20. The Rational Zero Point on Incentive-Object Preference Scales: A Developmental Study

    ERIC Educational Resources Information Center

    Haaf, Robert A.

    1971-01-01

    Preference judgments made by 20 males and 20 females (grades K-4) about the incentive value of 10 objects (i.e. bubble gum, Chiclet, candy corn, dried lima bean) helped determine relative and absolute scales for use of these objects as rewards. The assumption that the same object is equally rewarding at different age levels may be unwarranted.…

  1. Quantifying the Reuse of Learning Objects

    ERIC Educational Resources Information Center

    Elliott, Kristine; Sweeney, Kevin

    2008-01-01

    This paper reports the findings of one case study from a larger project, which aims to quantify the claimed efficiencies of reusing learning objects to develop e-learning resources. The case study describes how an online inquiry project "Diabetes: A waste of energy" was developed by searching for, evaluating, modifying and then integrating as many…

  2. The "Profiles" document: a modern revision of the objectives of undergraduate medical studies in Switzerland.

    PubMed

    Michaud, Pierre-André; Jucker-Kupper, Patrick; The Profiles Working Group

    2016-01-01

    The Joint Commission of the Swiss Medical Schools (SMIFK/CIMS) decided in 2000 to establish a Swiss Catalogue of Learning Objectives (SCLO) for undergraduate medical training, which was adapted from a similar Dutch blueprint. A second version of the SCLO was developed and launched in 2008. The catalogue is a prerequisite for the accreditation of the curricula of the six Swiss medical faculties and defines the contents of the Federal Licensing Examination (FLE). Given the evolution of the field of medicine and of medical education, the SMIFK/CIMS has decided to embark on a total revision of the SCLO. This article presents the proposed structure and content of Profiles, a new document which, in the future, will direct the format of undergraduate studies and of the FLE. Profiles stands for the Principal Relevant Objectives for Integrative Learning and Education in Switzerland. It is currently being developed by a group of experts from the six Swiss faculties as well as representatives of other institutions involved in these developments. The foundations of Profiles are grounded in the evolution of medical practice and of public health and are based on up-to-date teaching concepts, such as EPAs (entrustable professional activities). An introduction will cover the concepts and a tutorial will be displayed. Three main chapters will provide a description of the seven 2015 CanMEDS roles, a list of core EPAs and a series of ≈250 situations embracing the most frequent and current conditions affecting health. As Profiles is still a work in progress, it is hoped that this paper will attract the interest of all individuals involved in the training of medical students. PMID:26829005

  3. [Social marketing--seduction with the aim of healthy behavior?].

    PubMed

    Loss, J; Nagel, E

    2010-01-01

    SOCIAL MARKETING - SEDUCTION WITH THE AIM OF HEALTHY BEHAVIOR? Social marketing is the use of marketing principles to design and implement programs that promote socially beneficial behaviour change. Contrary to the marketing of consumption goods, social marketing does not deal with material products, but with behaviour, e. g. not smoking. This 'product' has a basic benefit (i. e. reduction of health risks in the long run), which is, however, difficult to convey. Therefore, the intended change in behaviour has to be related to a further reward which consists of symbolic goods, e. g. social appreciation or a better body feeling. The communication policy is essential for information on and motivation for the preventive issue. Social marketing campaigns whose development and management follow the principles of classical marketing can render preventive efforts more effective. In addition, social marketing can lead to a better quality management as compared to conventional preventive activities. These advantages can be explained by a) tailoring the campaign more specifically to the target group's needs and motives, b) presenting health risks more convincingly, and c) continuously analysing and evaluating the campaign and its effects. On the other hand, the marketing of preventive aims through mass media can bear several risks, as exemplified by different national and international public health campaigns. The necessity to communicate briefly and succinctly can lead to misleading simplifications and, in case of cancer screening, to the trivialization of a behaviour's consequences and adverse effects. Also, many campaigns do not intend to educate and inform, but try to persuade target persons of a certain behaviour, using emotions such as fear. This has led to social marketing being criticized as manipulation. Sometimes, social marketing campaigns cause stigma and discrimination of certain population subgroups, e. g. obese or HIV-positive people. Health promoters who plan

  4. Perceived Utility of the RE-AIM Framework for Health Promotion/Disease Prevention Initiatives for Older Adults: A Case Study from the U.S. Evidence-Based Disease Prevention Initiative.

    PubMed

    Ory, Marcia G; Altpeter, Mary; Belza, Basia; Helduser, Janet; Zhang, Chen; Smith, Matthew Lee

    2014-01-01

    Dissemination and implementation (D&I) frameworks are increasingly being promoted in public health research. However, less is known about their uptake in the field, especially for diverse sets of programs. Limited questionnaires exist to assess the ways that frameworks can be utilized in program planning and evaluation. We present a case study from the United States that describes the implementation of the RE-AIM framework by state aging services providers and public health partners and a questionnaire that can be used to assess the utility of such frameworks in practice. An online questionnaire was developed to capture community perspectives about the utility of the RE-AIM framework. Distributed to project leads in 27 funded states in an evidence-based disease prevention initiative for older adults, 40 key stakeholders responded representing a 100% state-participation rate among the 27 funded states. Findings suggest that there is perceived utility in using the RE-AIM framework when evaluating grand-scale initiatives for older adults. The RE-AIM framework was seen as useful for planning, implementation, and evaluation with relevance for evaluators, providers, community leaders, and policy makers. Yet, the uptake was not universal, and some respondents reported difficulties in use, especially adopting the framework as a whole. This questionnaire can serve as the basis to assess ways the RE-AIM framework can be utilized by practitioners in state-wide D&I efforts. Maximal benefit can be derived from examining the assessment of RE-AIM-related knowledge and confidence as part of a continual quality assurance process. We recommend such an assessment be performed before the implementation of new funding initiatives and throughout their course to assess RE-AIM uptake and to identify areas for technical assistance. PMID:25964897

  5. Perceived Utility of the RE-AIM Framework for Health Promotion/Disease Prevention Initiatives for Older Adults: A Case Study from the U.S. Evidence-Based Disease Prevention Initiative

    PubMed Central

    Ory, Marcia G.; Altpeter, Mary; Belza, Basia; Helduser, Janet; Zhang, Chen; Smith, Matthew Lee

    2015-01-01

    Dissemination and implementation (D&I) frameworks are increasingly being promoted in public health research. However, less is known about their uptake in the field, especially for diverse sets of programs. Limited questionnaires exist to assess the ways that frameworks can be utilized in program planning and evaluation. We present a case study from the United States that describes the implementation of the RE-AIM framework by state aging services providers and public health partners and a questionnaire that can be used to assess the utility of such frameworks in practice. An online questionnaire was developed to capture community perspectives about the utility of the RE-AIM framework. Distributed to project leads in 27 funded states in an evidence-based disease prevention initiative for older adults, 40 key stakeholders responded representing a 100% state-participation rate among the 27 funded states. Findings suggest that there is perceived utility in using the RE-AIM framework when evaluating grand-scale initiatives for older adults. The RE-AIM framework was seen as useful for planning, implementation, and evaluation with relevance for evaluators, providers, community leaders, and policy makers. Yet, the uptake was not universal, and some respondents reported difficulties in use, especially adopting the framework as a whole. This questionnaire can serve as the basis to assess ways the RE-AIM framework can be utilized by practitioners in state-wide D&I efforts. Maximal benefit can be derived from examining the assessment of RE-AIM-related knowledge and confidence as part of a continual quality assurance process. We recommend such an assessment be performed before the implementation of new funding initiatives and throughout their course to assess RE-AIM uptake and to identify areas for technical assistance. PMID:25964897

  6. Promoting the perception of two and three concurrent sound objects: An event-related potential study.

    PubMed

    Kocsis, Zsuzsanna; Winkler, István; Bendixen, Alexandra; Alain, Claude

    2016-09-01

    The auditory environment typically comprises several simultaneously active sound sources. In contrast to the perceptual segregation of two concurrent sounds, the perception of three simultaneous sound objects has not yet been studied systematically. We conducted two experiments in which participants were presented with complex sounds containing sound segregation cues (mistuning, onset asynchrony, differences in frequency or amplitude modulation or in sound location), which were set up to promote the perceptual organization of the tonal elements into one, two, or three concurrent sounds. In Experiment 1, listeners indicated whether they heard one, two, or three concurrent sounds. In Experiment 2, participants watched a silent subtitled movie while EEG was recorded to extract the object-related negativity (ORN) component of the event-related potential. Listeners predominantly reported hearing two sounds when the segregation promoting manipulations were applied to the same tonal element. When two different tonal elements received manipulations promoting them to be heard as separate auditory objects, participants reported hearing two and three concurrent sounds objects with equal probability. The ORN was elicited in most conditions; sounds that included the amplitude- or the frequency-modulation cue generated the smallest ORN amplitudes. Manipulating two different tonal elements yielded numerically and often significantly smaller ORNs than the sum of the ORNs elicited when the same cues were applied on a single tonal element. These results suggest that ORN reflects the presence of multiple concurrent sounds, but not their number. The ORN results are compatible with the horse-race principle of combining different cues of concurrent sound segregation. PMID:27374254

  7. Study of the impact of gas temperature and pressure on image quality of lithography objective lens

    NASA Astrophysics Data System (ADS)

    Zhou, Chao; Xing, Tingwen

    2013-08-01

    The aim of present work is to estimate the impact of gas refractive index shift on the image quality of projection lens caused by the change of environment condition. This work in the paper consists of two parts: a)when temperature rises or reduces, how gas refractive index changes and the wave front error comes up; b)when gas pressure changes. The model objective lens developed for simulation is a US patent lens whose NA <1 and wave front RMS < 5nm in all fields. This paper includes an illustration of the impact of gas refractive index shift on optical system data, wave front, and aberration. According to the analysis, wave front RMS of projection lens will increase about 10nm if the temperature changed by 0.1K or the gas pressure by 100 Pa. Comparing to origin wave front RMS of the patent lens, 5nm, the change caused by gas temperature and pressure can't be neglected. It proves the necessary of compensating or controlling the optical path change resulted from gas refractive index shift during the lithography projection lens work process.

  8. A Delphi study to curriculum modifying through the application of the course objective and competencies

    PubMed Central

    Taymoori, Parvaneh; Moshki, Mahdi

    2014-01-01

    Background: In order to incorporate new knowledge, skills and emerging concepts from dynamic fields of public health into ongoing courses reform of curriculums sounds necessary. Accordingly, this study was performed to modify health education curriculum of public health undergraduate level. Materials and Methods: Using Delphi technique, 18 health education lecturers from Tehran, Tabriz, Yazd, Shiraz, Gonabad, Ghazvin, Avhvaz and Kurdistan Universities Medical of Sciences based on their expertize in health education with PhD degree as scientific members, also 5 heads of departments according to working at health deputy for at least more than 5 years were asked during three rounds through panel experts to suggest and rate topics they deemed most important to graduate public health experts and curricula related to the areas of knowledge and skills in health education course. Results: The experts suggested that health enhancing behaviors and reduce health risks, advocate health, behavior change theories and developing a framework are key objects in the curriculum. Much more new topical outlines were related to previous course. Skills rated as important included need assessment and health communication. The most evaluators suggested that adding a practicum unit to two theory units will be helpful. Conclusion: The results from our survey suggested that changes in the course definition including new course objectives, topical outlines, and required skills were deemed important by the lecturers and were appropriately integrated into the health education course curriculum. The new curriculum should be evaluated constantly to seek and provide experiences that will best prepare students to meet challenges as a health educator. PMID:25540797

  9. The Shanghai Women's Asthma and Allergy Study: objectives, design, and recruitment results.

    PubMed

    Hartert, Tina V; Deng, Xinqing; Hartman, Terryl J; Wen, Wanqing; Yang, Gong; Gao, Yu-Tang; Jin, Meiling; Bai, Chunxue; Gross, Myron; Roberts, L Jackson; Sheller, James R; Christman, John; Dupont, William; Griffin, Marie; Shu, Xiao Ou

    2008-06-01

    The Shanghai Women's Asthma and Allergy Study is the first population-based incidence study designed to assess the associations of dietary antioxidant intake and measures of oxidative stress and antioxidant enzyme activity with development of adult-onset asthma and allergic rhinitis. A total of 65,732 participants in the Shanghai Women's Health Study, an ongoing cohort study in seven districts of Shanghai, People's Republic of China, were recruited to the Shanghai Women's Asthma and Allergy Study from 2003 to 2007. Dietary intake was assessed in the parent study by using a validated and quantitative food frequency questionnaire at baseline recruitment and at the first biennial follow-up survey. Blood and urine samples were collected to measure baseline oxidative stress, antioxidant enzyme activity, and nutrient levels at the baseline survey. Incident asthma and allergic rhinitis were assessed by using a modification of the International Study of Asthma and Allergies in Childhood questionnaire during the biennial in-person survey of the Shanghai Women's Health Study. Diagnosis of asthma was confirmed by either methacholine challenge testing or test of reversibility to beta-agonists. Dietary antioxidant intake, plasma antioxidants, antioxidant enzymes, and urinary isoprostanes, a marker of oxidative stress, were measured prior to disease onset. This paper describes the study objectives, design, population demographics, and recruitment results. PMID:18397914

  10. The Shanghai Women’s Asthma and Allergy Study: Objectives, Design, and Recruitment Results

    PubMed Central

    Hartert, Tina V.; Deng, Xinqing; Hartman, Terryl J.; Wen, Wanqing; Yang, Gong; Gao, Yu-Tang; Jin, Meiling; Bai, Chunxue; Gross, Myron; Roberts, L. Jackson; Sheller, James R.; Christman, John; Dupont, William; Griffin, Marie; Shu, Xiao Ou

    2008-01-01

    The Shanghai Women’s Asthma and Allergy Study is the first population-based incidence study designed to assess the associations of dietary antioxidant intake and measures of oxidative stress and antioxidant enzyme activity with development of adult-onset asthma and allergic rhinitis. A total of 65,732 participants in the Shanghai Women’s Health Study, an ongoing cohort study in seven districts of Shanghai, People’s Republic of China, were recruited to the Shanghai Women’s Asthma and Allergy Study from 2003 to 2007. Dietary intake was assessed in the parent study by using a validated and quantitative food frequency questionnaire at baseline recruitment and at the first biennial follow-up survey. Blood and urine samples were collected to measure baseline oxidative stress, antioxidant enzyme activity, and nutrient levels at the baseline survey. Incident asthma and allergic rhinitis were assessed by using a modification of the International Study of Asthma and Allergies in Childhood questionnaire during the biennial in-person survey of the Shanghai Women’s Health Study. Diagnosis of asthma was confirmed by either methacholine challenge testing or test of reversibility to beta-agonists. Dietary antioxidant intake, plasma antioxidants, antioxidant enzymes, and urinary isoprostanes, a marker of oxidative stress, were measured prior to disease onset. This paper describes the study objectives, design, population demographics, and recruitment results. PMID:18397914

  11. Aiming at Targets: The Autobiography of Robert C. Seamans, Jr.

    NASA Technical Reports Server (NTRS)

    Seamans, Robert C., Jr.

    1996-01-01

    Bob Seamans originally was inspired to write this book for his family and friends. That is a large audience. By his own count his immediate family numbers twenty-four, not counting brothers and cousins and their families. His friends are uncounted but surely run to hundreds. As one of them and as a colleague at NASA, I am pleased and honored that he asked me to write this foreword. While written in Bob's unique and informal style, this autobiography has significance for many readers beyond his large circles of family and friends. Leaders and students of large, complex technological endeavors should be able to learn much from reading how Bob faced the daunting technical and management challenges in his career. As the title of this book implies, Bob has always set high goals for himself and then kept his eyes focused on both the necessary details and the broader picture. His ability to shift smoothly among jobs that required seemingly disparate abilities and skills speaks volumes about his insight, dedication, and enthusiasm for achievement. The book spans a truly remarkable life story. Bob first takes us through his growing up, education, and early professional and family life. Next he focuses on the crucial years when he was the general manager of NASA. Then he moves on to his career in the top jobs at the Air Force, the National Academy of Engineering, and the Energy Research and Development Administration. Finally, he touches on his later leadership activities in the academic and business worlds. Aiming at Targets is a series of fascinating topical vignettes covering his professional life. Taken together, like broad brushstrokes in an impressionist painting, they give a better picture of Bob Seamans and his work than a detailed recitation of facts and dates could hope to do. This is a cheerful account of an interesting and successful career. The book is full of good stories, with many memorable characters. Like the proverbial sundial, it counts the sunny hours

  12. The Friendly Object

    ERIC Educational Resources Information Center

    Prangnell, Peter

    1969-01-01

    If buildings and cities are made as friendly objects, they will invite and precipitate participation. They will stimulate our creative powers, which are the basis of growth in all our activities. (CK)

  13. Mechanical Objects and the Engineering Learner: An Experimental Study of How the Presence of Objects Affects Students' Performance on Engineering Related Tasks

    ERIC Educational Resources Information Center

    Bairaktarova, Diana N.

    2013-01-01

    People display varying levels of interaction with the mechanical objects in their environment; engineers in particular as makers and users of these objects display a higher level of interaction with them. Investigating the educational potential of mechanical objects in stimulating and supporting learning in engineering is warranted by the fact…

  14. A Study of Planetary Nebulae using the Faint Object Infrared Camera for the SOFIA Telescope

    NASA Technical Reports Server (NTRS)

    Davis, Jessica

    2012-01-01

    A planetary nebula is formed following an intermediate-mass (1-8 solar M) star's evolution off of the main sequence; it undergoes a phase of mass loss whereby the stellar envelope is ejected and the core is converted into a white dwarf. Planetary nebulae often display complex morphologies such as waists or torii, rings, collimated jet-like outflows, and bipolar symmetry, but exactly how these features form is unclear. To study how the distribution of dust in the interstellar medium affects their morphology, we utilize the Faint Object InfraRed CAmera for the SOFIA Telescope (FORCAST) to obtain well-resolved images of four planetary nebulae--NGC 7027, NGC 6543, M2-9, and the Frosty Leo Nebula--at wavelengths where they radiate most of their energy. We retrieve mid infrared images at wavelengths ranging from 6.3 to 37.1 micron for each of our targets. IDL (Interactive Data Language) is used to perform basic analysis. We select M2-9 to investigate further; analyzing cross sections of the southern lobe reveals a slight limb brightening effect. Modeling the dust distribution within the lobes reveals that the thickness of the lobe walls is higher than anticipated, or rather than surrounding a vacuum surrounds a low density region of tenuous dust. Further analysis of this and other planetary nebulae is needed before drawing more specific conclusions.

  15. Aim for the Inner Life: Teaching Early Teens.

    ERIC Educational Resources Information Center

    Regelski, Thomas A.

    1979-01-01

    Music study should be construed primarily as an experience of its feeling content. Taught so, it can reach for the inner core of the early adolescent, to pierce that sometimes hard outer surface that protects the vulnerable inner life. Attempts to intellectualize music with young teens are doomed. (Author/SJL)

  16. Perceived environment in relation to objective and self-reported physical activity in Spanish youth. The UP&DOWN study.

    PubMed

    Garcia-Cervantes, Laura; Rodríguez-Romo, Gabriel; Esteban-Cornejo, Irene; Cabanas-Sanchez, Verónica; Delgado-Alfonso, Álvaro; Castro-Piñero, José; Veiga, Óscar L

    2016-08-01

    The aims of the present study were to assess the association of environmental perception with objective and self-reported physical activity (PA) and the relation between environmental perception and meeting PA recommendations on children and adolescents. A sample of 1520 youth (770 boys) aged 8-18 years (12.1 ± 2.5 years) from the UP&DOWN study were included in the data analyses. Environmental perception was assessed with the short adapted version of the ALPHA environmental questionnaire. PA was objectively (accelerometers) and self-reported measured (PA Questionnaire for Children, Patient-centered Assessment and Counseling for Exercise Questionnaire and Finnish PA Index). Linear regression models were used to assess the association of environmental perception with PA. Bivariate logistic regression models were used to assess differences between environmental perception and meeting PA recommendations. Environmental perception was positively associated with both objective and self-reported PA. Some differences were found in the association of environmental perception and PA between sex- and age-specific groups. Youth who perceived a more favourable environment were more likely to meet PA recommendations (at least 60 min · day(-1) of moderate to vigorous PA (MVPA)). Results suggest that environmental perceptions of children and adolescents may play an important role in achieving higher levels of PA. PMID:26641935

  17. Bridging the Digital Divide, Aiming to Become Lifelong Learners

    NASA Astrophysics Data System (ADS)

    Kachelhoffer, Annelise; Khine, Myint Swe

    Studies in the past documented that proper use of Information and Communication Technology (ICT) can positively impact learning. It has been shown that the use of ICT can help students develop inquiry and thinking skills, increase learning opportunities, enhance learning activities, and improve learning outcomes for students. While there are bright prospects, barriers still exist in certain areas, particularly the readiness of the teachers who will adopt the technology, administrative support and technology infrastructure in schools. This study reports the patterns of computer use and computer self-efficacy among students in a postgraduate degree in education program in the UAE. The survey from 91 students were analysed and found that most students have positive attitudes and beliefs in ICT, but lacking behind the use of such technologies. The authors suggest that it is necessary to create opportunities for them to use ICT in the classroom and further develop knowledge and skills in Web 2.0 technologies.

  18. Meeting the Aims of Honors in the Online Environment

    ERIC Educational Resources Information Center

    Johnson, Melissa L.

    2013-01-01

    While little data-based research is available on the use of technology in the honors classroom, data on the nature of online honors courses are even rarer. In undergraduate education generally, enrollment in online courses has been increasing annually, outpacing enrollment in traditional, face-to-face environments. During fall 2011, more than 6.7…

  19. The Writing Cure: Psychoanalysis, Composition, and the Aims of Education.

    ERIC Educational Resources Information Center

    Bracher, Mark

    Asserting that psychoanalysis and writing instruction have much to offer each other, this book examines the intersection between these two fields and proposes pedagogical uses of psychoanalytic technique for writing instruction. Articulating an approach based on the work of Jacques Lacan, the book shows how a psychoanalytic perspective can offer…

  20. The airborne mass spectrometer AIMS - Part 1: AIMS-H2O for UTLS water vapor measurements

    NASA Astrophysics Data System (ADS)

    Kaufmann, Stefan; Voigt, Christiane; Jurkat, Tina; Thornberry, Troy; Fahey, David W.; Gao, Ru-Shan; Schlage, Romy; Schäuble, Dominik; Zöger, Martin

    2016-03-01

    In the upper troposphere and lower stratosphere (UTLS), the accurate quantification of low water vapor concentrations has presented a significant measurement challenge. The instrumental uncertainties are passed on to estimates of H2O transport, cloud formation and the role of H2O in the UTLS energy budget and resulting effects on surface temperatures. To address the uncertainty in UTLS H2O determination, the airborne mass spectrometer AIMS-H2O, with in-flight calibration, has been developed for fast and accurate airborne water vapor measurements. We present a new setup to measure water vapor by direct ionization of ambient air. Air is sampled via a backward facing inlet that includes a bypass flow to assure short residence times (< 0.2 s) in the inlet line, which allows the instrument to achieve a time resolution of ˜ 4 Hz, limited by the sampling frequency of the mass spectrometer. From the main inlet flow, a smaller flow is extracted into the novel pressure-controlled gas discharge ion source of the mass spectrometer. The air is directed through the gas discharge region where ion-molecule reactions lead to the production of hydronium ion clusters, H3O+(H2O)n (n = 0, 1, 2), in a complex reaction scheme similar to the reactions in the D-region of the ionosphere. These ions are counted to quantify the ambient water vapor mixing ratio. The instrument is calibrated during flight using a new calibration source based on the catalytic reaction of H2 and O2 on a Pt surface to generate a calibration standard with well-defined and stable H2O mixing ratios. In order to increase data quality over a range of mixing ratios, two data evaluation methods are presented for lower and higher H2O mixing ratios respectively, using either only the H3O+(H2O) ions or the ratio of all water vapor dependent ions to the total ion current. Altogether, a range of water vapor mixing ratios from 1 to 500 parts per million by volume (ppmv) can be covered with an accuracy between 7 and 15 %. AIMS

  1. Space Object Characterization Studies and the Magdalena Ridge Observatory's 2.4-meter Telescope

    NASA Astrophysics Data System (ADS)

    Ryan, E.; Ryan, W.

    The Magdalena Ridge Observatory's (MRO) fast-tracking 2.4-meter telescope is located at 10,612 feet atop the Magdalena Mountains in Central New Mexico, and is presently transitioning to an operational status. The MRO 2.4-meter is one of the largest telescopes in the world that has as its primary mission the physical characterization of small bodies (both natural and artificial) in the Solar System. The 2.4-meter's control system is designed to provide convenient and accurate non-sidereal tracking, and the telescope is capable of rapid movement (slew rates are up to 15 degrees/sec) making it an ideal instrument for non-resolved imaging of low-Earth orbit (LEO) space objects. The 2.4-meter telescope can accommodate a wide variety of instrument systems, and support the fabrication, integration, and operation of new instrumentation as well as the development of new and innovative techniques in space object identification studies. Currently, we are investigating various methods to enhance and improve existing capabilities for unique discrimination of resident space objects. The temporal brightness variations (i.e., lightcurves) of unresolved targets such as artificial satellites can be used to develop a powerful tool for general characterization studies. Analysis of these temporal signatures permits the extraction of pertinent distinguishing features, and may also be an indicator for a change in general health status of a satellite. Payne (2005) and Gregory (2005) have demonstrated what can be obtained by adding multi-color information to traditional photometric intensity measurements for geosynchronous satellites. Our current focus is to introduce supplementary discriminators, including polarization data and simultaneously obtained spectral and temporal data. We will discuss new methods for incorporating such data, with a specific emphasis toward LEOs as our target objects. Our observing strategy will be to choose a statistically robust target set with know properties

  2. The airborne mass spectrometer AIMS - Part 1: AIMS-H2O for UTLS water vapor measurements

    NASA Astrophysics Data System (ADS)

    Kaufmann, S.; Voigt, C.; Jurkat, T.; Thornberry, T.; Fahey, D. W.; Gao, R.-S.; Schlage, R.; Schäuble, D.; Zöger, M.

    2015-12-01

    In the upper troposphere and lower stratosphere (UTLS), the accurate quantification of low water vapor concentrations has presented a significant measurement challenge. The instrumental uncertainties are passed on to estimates of H2O transport, cloud formation and the H2O role in the UTLS energy budget and resulting effects on surface temperatures. To address the uncertainty in UTLS H2O determination, the airborne mass spectrometer AIMS-H2O, with in-flight calibration, has been developed for fast and accurate airborne water vapor measurements. We present the new setup to measure water vapor by direct ionization of ambient air. Air is sampled via a backward facing inlet that includes a bypass flow to assure short residence times (< 0.2 s) in the inlet line, which allows the instrument to achieve a time resolution of ∼ 4 Hz. From the main inlet flow, a smaller flow is extracted into the novel pressure-controlled gas discharge ion source of the mass spectrometer. The air is directed through the gas discharge region where water molecules react to form hydronium ion clusters, H3O+(H2O)n (n= 0, 1, 2), in a complex reaction scheme similar to the reactions in the D-region of the ionosphere. These ions are counted to quantify the ambient water vapor mixing ratio. The instrument is calibrated during flight using a new calibration source based on the catalytic reaction of H2 and O2 on a Pt surface to generate a calibration standard with well defined and stable H2O mixing ratios. In order to increase data quality over a range of mixing ratios, two data evaluation methods are presented for lower and higher H2O mixing ratios respectively, using either only the H3O+(H2O) ions or the ratio of all water vapor dependent ions to the total ion current. Altogether, a range of water vapor mixing ratios from 1 to 500 ppmv (mole ratio, 10-6 mol mol-1) can be covered with an accuracy between 7 and 15 %. AIMS-H2O was deployed on two DLR research aircraft, the Falcon during CONCERT

  3. A subjective study and an objective metric to quantify the granularity level of textures

    NASA Astrophysics Data System (ADS)

    Subedar, Mahesh M.; Karam, Lina J.

    2015-03-01

    Texture granularity is an important visual characteristic that is useful in a variety of applications, including analysis, recognition, and compression, to name a few. A texture granularity measure can be used to quantify the perceived level of texture granularity. The granularity level of the textures is influenced by the size of the texture primitives. A primitive is defined as the smallest recognizable repetitive object in the texture. If the texture has large primitives then the perceived granularity level tends to be lower as compared to a texture with smaller primitives. In this work we are presenting a texture granularity database referred as GranTEX which consists of 30 textures with varying levels of primitive sizes and granularity levels. The GranTEX database consists of both natural and man-made textures. A subjective study is conducted to measure the perceived granularity level of textures present in the GranTEX database. An objective metric that automatically measures the perceived granularity level of textures is also presented as part of this work. It is shown that the proposed granularity metric correlates well with the subjective granularity scores.

  4. Surgeons' aims and pain assessment strategies when managing paediatric post-operative pain: A qualitative study.

    PubMed

    Twycross, Alison M; Williams, Anna M; Finley, G Allen

    2015-12-01

    Children experience moderate to severe pain post-operatively. Nurses have been found to have a variety of aims in this context. Surgeons' aims when managing post-operative pain have not been explored. This qualitative study set out to explore paediatric surgeons' aims when managing post-operative pain in one paediatric hospital in Canada. Consultant surgeons (n = 8) across various specialities took part in semi-structured interviews. Surgeons' overarching aim was to keep the child comfortable. Various definitions of comfortable were given, relating to the child's experience of pain itself and their ability to undertake activities of daily living. Children's behavioural pain cues seem to be a primary consideration when making treatment decisions. Parents' views regarding their child's pain were also seen as important, suggesting children may not be seen as competent to make decisions on their own behalf. The need to maintain a realistic approach was emphasised and pain management described as a balancing act. Surgeons may draw on both tacit and explicit knowledge when assessing children's pain. There appears to be an expectation among surgeons that some pain is to be expected post-operatively and that the diagnostic value of pain may, in some cases, supersede concerns for the child's pain experience. PMID:24728398

  5. Field Experiments Aimed To The Analysis of Flood Generation Processes

    NASA Astrophysics Data System (ADS)

    Carriero, D.; Iacobellis, V.; Oliveto, G.; Romano, N.; Telesca, V.; Fiorentino, M.

    The study of the soil moisture dynamics and of the climate-soil-vegetation interac- tion is essential for the comprehension of possible climatic change phenomena, as well as for the analysis of occurrence of extreme hydrological events. In this trend the theoretically-based distribution of floods recently derived by Fiorentino and Ia- cobellis, [ŞNew insights about the climatic and geologic control on the probability distribution of floodsT, Water Resources Research, 2001, 37: 721-730] demonstrated, by an application in some Southern Italy basins, that processes at the hillslope scale strongly influence the basin response by means of the different mechanisms of runoff generation produced by various distributions of partial area contributing. This area is considered as a stochastic variable whose pdf position parameter showed strong de- pendence on the climate as it can seen in the studied basins behavior: in dry zones, where there is the prevalence of the infiltration excess (Horton) mechanism, the basin water loss parameter decreases as basin area increases and the flood peak source area depends on the permeability of soils; in humid zones, with the prevalence of satu- ration excess (Dunne) process, the loss parameter seems independent from the basin area and very sensitive to simple climatic index while only small portion of the area invested by the storm contributes to floods. The purpose of this work is to investigate the consistency of those interpretations by means of field experiments at the hillslope scale to establish a parameterization accounting for soil physical and hydraulic prop- erties, vegetation characteristics and land-use. The research site is the catchment of River Fiumarella di Corleto, which is located in Basilicata Region, Italy, and has a drainage area of approximately 32 km2. The environment has a rather dynamic geo- morphology and very interesting features from the soil-landscape modeling viewpoint [Santini A., A. Coppola, N. Romano, and

  6. Objective sleep of older primiparous Japanese women during the first 4 months postpartum: an actigraphic study.

    PubMed

    Iwata, Hiroko; Mori, Emi; Tsuchiya, Miyako; Sakajo, Akiko; Saeki, Akiko; Maehara, Kunie; Ozawa, Harumi; Morita, Akiko; Maekawa, Tomoko

    2015-03-01

    This longitudinal study was designed to examine objective sleep parameters of older primiparous Japanese women during the first 4 months postpartum using actigraphy. The participants were 18 older primiparae (Mean (SD) = 37.06 (2.62) years, range 35-44 years) who gave birth to healthy neonates at one of three urban Japanese hospitals. Objective sleep quality was measured using actigraphy for 48 h at 1, 2 and 4 months postpartum. The Friedman test was used to test for differences in sleep parameters across time. Sleep duration (SMIN) increased significantly from 2 months (Mean (M) = 301.94 min) to 4 months (M = 372.78 min). Sleep efficiency (SE) increased significantly from 1 month (73.52%) to 2 (86.66%) and 4 months (89.05%). Waking after sleep onset (WASO) decreased significantly from 1 month (M = 114.64 min) to 2 (M = 40.18 min) and 4 months (M = 38.36 min) and long waking episodes (LWEP) significantly decreased from 1 month (4.67) to 2 (2.69) and 4 months (3.12). Persistent postpartum sleep problems can be a sign of postpartum depression as well as health problems among infants. PMID:25759196

  7. Long-term integrated radiophysical studies of the ionosphere, near space, and the propagation of radio waves from space objects

    NASA Technical Reports Server (NTRS)

    Misyura, V. A.

    1974-01-01

    The radiophysical studies reported consist of direct measurements of certain effects induced in the propagation of radio waves from space objects. From measured effects and from data on the motion and position of space objects, physical parameters of the medium and bodies are determined.

  8. Criteria for the Evaluation of Learning Objectives in the Education of Health Personnel. Report of a WHO Study Group.

    ERIC Educational Resources Information Center

    World Health Organization, Geneva (Switzerland).

    Because there is a growing interest in improving the efficiency, effectiveness, and relevance of health personnel education, the World Health Organization formed a Study Group to discuss the uses of learner-oriented objectives, to examine the bases for identifying and selecting educational objectives, and to devise guidelines for evaluating such…

  9. Arthroscopic verification of objectivity of the orthopaedic examination and magnetic resonance imaging in intra-articular knee injury. Retrospective study

    PubMed Central

    Skowronek, Michał; Skowronek, Paweł; Dutka, Łukasz

    2011-01-01

    Introduction Arthroscopy of the knee joint is regarded as the most objective diagnostic method in intra-articular knee joint lesions. Aim The purpose of this study was to assess the objectivity and diagnostic value of orthopaedic examination (OE) and magnetic resonance imaging (MRI) in reference to the arthroscopic result. Material and methods In a group of 113 patients treated by arthroscopic surgery for post-traumatic knee pathology between 2008 and 2010 in our department, accuracy of clinical and MRI findings that preceded surgery were studied retrospectively using a statistical method. Sensitivity, specificity, accuracy and predictive negative and positive values were the subject of analysis. Results In the presented trial, sensitivity values of the orthopaedic examination for injuries of the anterior cruciate ligament (ACL), meniscus medialis (MM), meniscus lateralis (ML) and chondral injuries (ChI) were 86%, 65%, 38% and 51%, respectively. Specificity values were 90%, 65%, 100% and 100%, respectively. The MR sensitivity and specificity values were 80%, 88%, 44% and 32%, and 86%, 64%, 93% and 97%, respectively. Conclusions Assessment of intra-articular knee joint lesions is a difficult diagnostic problem. In making a decision about arthroscopy of the knee joint, an appropriate sequence of examinations should be carried out: OE, MRI and arthroscopy. The improvement in the effectiveness of the orthopaedic examination and MRI can limit the too high frequency of diagnostic arthroscopies, which generates the risk of operation treatment and costs. PMID:23255995

  10. Objective sleep, a novel risk factor for alterations in kidney function: the CARDIA Study

    PubMed Central

    Petrov, Megan E.; Kim, Yongin; Lauderdale, Diane S.; Lewis, Cora E.; Reis, Jared P.; Carnethon, Mercedes R.; Knutson, Kristen L.; Glasser, Stephen P.

    2014-01-01

    Objective To determine the association between objectively measured sleep and 10-year changes in estimated glomerular filtration rate (eGFR). Methods From 2003 to 2005, an ancillary sleep study was conducted at the Chicago site of the Coronary Artery Disease in Young Adults (CARDIA) study. Community-based black and white adults (aged 32–51 years) wore a wrist actigraph up to six nights to record sleep duration and fragmentation. Sleep quality was measured with the Pittsburgh Sleep Quality Index (PSQI). Participants without history of cardiovascular or chronic kidney diseases, proteinuria, or hypertension at the 2000–2001 CARDIA examination were followed over 10 years (n = 463). eGFR was estimated from serum creatinine (eGFRCr) at the 2000–2001, 2005–2006, and 2010–2011 CARDIA examinations, whereas cystatin-C-estimated eGFR (eGFRCys) was measured at the 2000–2001 and 2005–2006 examinations. Generalized estimating equation regression and linear models estimated the associations of each sleep parameter with changes in eGFRCr and eGFRCys, controlling for cardiovascular and renal risk. Results Sleep parameters were not related to 5-year change in eGFRCys. However, each 1 h decrease in sleep duration was significantly associated with a 1.5 mL/min/1.73 m2 higher eGFRCr [95% confidence interval (CI), 0.2–2.7], and each one-point increase in PSQI was significantly associated with a 0.5 mL/min/1.73 m2 higher eGFRCr (95% CI, 0.04–0.9) over 10 years. Conclusion In this community-based sample, shorter sleep and poorer sleep quality were related to higher kidney filtration rates over 10 years. PMID:25037841

  11. A STUDY OF THE IMAGE QUALITY OF COMPUTED TOMOGRAPHY ADAPTIVE STATISTICAL ITERATIVE RECONSTRUCTED BRAIN IMAGES USING SUBJECTIVE AND OBJECTIVE METHODS.

    PubMed

    Mangat, J; Morgan, J; Benson, E; Båth, M; Lewis, M; Reilly, A

    2016-06-01

    The recent reintroduction of iterative reconstruction in computed tomography has facilitated the realisation of major dose saving. The aim of this article was to investigate the possibility of achieving further savings at a site with well-established Adaptive Statistical iterative Reconstruction (ASiR™) (GE Healthcare) brain protocols. An adult patient study was conducted with observers making visual grading assessments using image quality criteria, which were compared with the frequency domain metrics, noise power spectrum and modulation transfer function. Subjective image quality equivalency was found in the 40-70% ASiR™ range, leading to the proposal of ranges for the objective metrics defining acceptable image quality. Based on the findings of both the patient-based and objective studies of the ASiR™/tube-current combinations tested, 60%/305 mA was found to fall within all, but one, of these ranges. Therefore, it is recommended that an ASiR™ level of 60%, with a noise index of 12.20, is a viable alternative to the currently used protocol featuring a 40% ASiR™ level and a noise index of 11.20, potentially representing a 16% dose saving. PMID:27103646

  12. Photometric Study of the FU Orionis Object BBW 76 from the Bamberg Observatory Southern Sky Survey

    NASA Astrophysics Data System (ADS)

    Borisova, A.; Tsvetkova, K. P.; Tsvetkov, M. K.

    2006-04-01

    The Bamberg Observatory Southern Sky Survey provided 93 photographic plates with the FU Orionis object BBW 76, clearly detectable in the time interval 1963-1976. We perform aperture photometry of BBW 76 from the 2 x 2 degrees area near target star scanned with the Epson Expression 1640 XL flatbed scanner. For each plate a transformation of plate magnitude to the GSC 2.2 magnitudes in B photographic band was found out for selected reference stars, and used for deriving B magnitudes of BBW 76. The analysis of the photometric behaviour of BBW 76 is presented.

  13. Recent developments in atomic/nuclear methodologies used for the study of cultural heritage objects

    NASA Astrophysics Data System (ADS)

    Appoloni, Carlos Roberto

    2013-05-01

    Archaeometry is an area established in the international community since the 60s, with extensive use of atomic-nuclear methods in the characterization of art, archaeological and cultural heritage objects in general. In Brazil, however, until the early '90s, employing methods of physics, only the area of archaeological dating was implemented. It was only after this period that Brazilian groups became involved in the characterization of archaeological and art objects with these methodologies. The Laboratory of Applied Nuclear Physics, State University of Londrina (LFNA/UEL) introduced, pioneered in 1994, Archaeometry and related issues among its priority lines of research, after a member of LFNA has been involved in 1992 with the possibilities of tomography in archaeometry, as well as the analysis of ancient bronzes by EDXRF. Since then, LFNA has been working with PXRF and Portable Raman in several museums in Brazil, in field studies of cave paintings and in the laboratory with material sent by archaeologists, as well as carrying out collaborative work with new groups that followed in this area. From 2003/2004 LAMFI/DFN/IFUSP and LIN/COPPE/UFRJ began to engage in the area, respectively with methodologies using ion beams and PXRF, then over time incorporating other techniques, followed later by other groups. Due to the growing number of laboratories and institutions/archaeologists/conservators interested in these applications, in may 2012 was created a network of available laboratories, based at http://www.dfn.if.usp.br/lapac. It will be presented a panel of recent developments and applications of these methodologies by national groups, as well as a sampling of what has been done by leading groups abroad.

  14. Recent developments in atomic/nuclear methodologies used for the study of cultural heritage objects

    SciTech Connect

    Appoloni, Carlos Roberto

    2013-05-06

    Archaeometry is an area established in the international community since the 60s, with extensive use of atomic-nuclear methods in the characterization of art, archaeological and cultural heritage objects in general. In Brazil, however, until the early '90s, employing methods of physics, only the area of archaeological dating was implemented. It was only after this period that Brazilian groups became involved in the characterization of archaeological and art objects with these methodologies. The Laboratory of Applied Nuclear Physics, State University of Londrina (LFNA/UEL) introduced, pioneered in 1994, Archaeometry and related issues among its priority lines of research, after a member of LFNA has been involved in 1992 with the possibilities of tomography in archaeometry, as well as the analysis of ancient bronzes by EDXRF. Since then, LFNA has been working with PXRF and Portable Raman in several museums in Brazil, in field studies of cave paintings and in the laboratory with material sent by archaeologists, as well as carrying out collaborative work with new groups that followed in this area. From 2003/2004 LAMFI/DFN/IFUSP and LIN/COPPE/UFRJ began to engage in the area, respectively with methodologies using ion beams and PXRF, then over time incorporating other techniques, followed later by other groups. Due to the growing number of laboratories and institutions/archaeologists/conservators interested in these applications, in may 2012 was created a network of available laboratories, based at http://www.dfn.if.usp.br/lapac. It will be presented a panel of recent developments and applications of these methodologies by national groups, as well as a sampling of what has been done by leading groups abroad.

  15. A Study of the Variability of Water Maser Emission in a Sample of Young Stellar Objects

    NASA Astrophysics Data System (ADS)

    Trinidad, M. A.; Rojas, V.; Plascencia, J. C.; Ricalde, A.; Curiel, S.; Rodríguez, L. F.

    We present results of water maser observations in a sample of young stellar objects. The observations were made using the Haystack 37 m antenna during a span of time of about eight months. The sample was selected to study the variability of the water maser emission in young sources with far-infrared luminosities between 260 and 2.5×10^4 L[sun]. The results are shown in a series of plots that allow the analysis of the variation of the maser emission and to discuss the global properties of the sample. The results show that in all the observed sources the water maser emission varies with time. Based on the observed variability, the sample shows two kinds of behavior. About half of the sources show large variations in the peak flux density of at least one feature (by more than an order of magnitude) in time spans between one and several months, while in all the sources there is more than one feature where the changes in peak flux density are smaller (by less than a factor of 10) but in similar time scales. Finally, the variability of the observed water maser emission does not show a clear periodicity pattern in time and we do not find a clear relationship between the luminosity of the sources and the water maser variability. >From a statistical point of view, the H[2]O maser variability can be described as due to small (10%) Gaussian fluctuations in the line opacity.

  16. A molecular line study towards massive extended green object clumps in the southern sky: chemical properties

    NASA Astrophysics Data System (ADS)

    Yu, Naiping; Wang, Jun-Jie

    2015-08-01

    We present a molecular line study towards 31 extended green object (EGO) clumps in the southern sky using data from MALT90 (Millimetre Astronomy Legacy Team 90 GHz). According to previous multiwavelength observations, we divide our sample into two groups: massive young stellar objects (MYSOs) and H II regions. The most detected lines are N2H+ (J = 1 - 0), HCO+ (J = 1 - 0), HNC (J = 1 - 0), HCN (J = 1 - 0), HC3N (J = 10 - 9), H13CO+ (J = 1 - 0), C2H (N = 1 - 0) and SiO (J = 2 - 1), indicating that most EGOs are indeed associated with dense clumps and recent outflow activities. The velocity widths of the N2H+ (J = 1 - 0), H13CO+ (J = 1 - 0), C2H (N = 1 - 0) and HC3N (J = 10 - 9) lines are comparable to each other in MYSOs. However, in H II regions the velocity widths of the N2H+ (J = 1 - 0) and C2H (N = 1 - 0) lines tend to be narrower than those of H13CO+ (J = 1 - 0) and HC3N (J = 10 - 9). Our results seem to support that N2H+ and C2H emissions mainly come from the gas inside quiescent clumps. In addition, we also find that the [N2H+]/[H13CO+] and [C2H]/[H13CO+] relative abundance ratios decrease from MYSOs to H II regions. These results suggest depletion of N2H+ and C2H in the late stages of massive-star formation, probably caused by the formation of H II regions inside. N2H+ and C2H might be used as chemical clocks for massive-star formation by comparing with other molecules such as H13CO+ and HC3N.

  17. The gas environment of the young stellar object GL 2591 studied by infrared spectroscopy

    NASA Technical Reports Server (NTRS)

    Mitchell, George F.; Curry, Charles; Maillard, Jean-Pierre; Allen, Mark

    1989-01-01

    High-resolution M band (4.6 microns) spectroscopy of GL 2591 is presented. Physical structures noted include an absorption feature with an outflow velocity of about 17 km/s, cold gas (identified with the core of the molecular cloud within which the object is embedded), and very broad C-12O lines formed in a neutral wind. The detection of hot low-velocity gas together with warm high-velocity gas suggests the scenario of a warm neutral wind accelerating from an accretion disk.

  18. The gas environment of the young stellar object GL 2591 studied by infrared spectroscopy

    SciTech Connect

    Mitchell, G.F.; Curry, C.; Maillard, J.; Allen, M.; CNR, Institut d'Astrophysique, Paris; California Institute of Technology, Pasadena )

    1989-06-01

    High-resolution M band (4.6 microns) spectroscopy of GL 2591 is presented. Physical structures noted include an absorption feature with an outflow velocity of about 17 km/s, cold gas (identified with the core of the molecular cloud within which the object is embedded), and very broad C-12O lines formed in a neutral wind. The detection of hot low-velocity gas together with warm high-velocity gas suggests the scenario of a warm neutral wind accelerating from an accretion disk. 32 refs.

  19. The Healthy Brains and Behavior Study: objectives, design, recruitment, and population coverage.

    PubMed

    Liu, Jianghong; Richmond, Therese S; Raine, Adrian; Cheney, Rose; Brodkin, Edward S; Gur, Ruben C; Gur, Raquel E

    2013-09-01

    Violence is increasingly viewed as a public health issue that may be ameliorated by health-based interventions. The Healthy Brains and Behavior Study (HBBS) aims to identify environmental and biological risk factors for aggression in late childhood and to reduce aggression through psychological and nutritional treatments. Utilizing a cross-disciplinary collaborative research approach, the HBBS has both human and animal components. The human component has two stages consisting of risk assessment followed by treatment. The risk assessment is based on 451 community-residing children aged 11-12 years and their caregivers, during which genetic, brain imaging, neuroendocrine, psychophysiology, environment toxicology, neurocognitive, nutrition, psychological, social and demographic risk variables are collected. Children who met criteria (N = 219) for problematic aggressive behaviors were assigned to one of four treatment groups: cognitive-behavior therapy (CBT) alone, nutritional supplements alone, both CBT and nutrition, or treatment-as-usual. Treatment duration was 12 weeks and all children whether in treatment or not were followed-up at three, six, and 12 months. The animal component assessed the effects of dietary omega-3 fatty acids on the development of aggression. This study contributes knowledge on how biological factors interact with social factors in shaping proactive and reactive aggression and assesses the efficacy of treatment approaches to reduce childhood aggression. PMID:25931327

  20. Taking aim at the ABM Treaty: THAAD and US Security

    SciTech Connect

    Pike, J.; Corbin, M.

    1995-05-01

    Successful testing of the Army`s Theater High Altitude Area Defense interceptor missile leads to speculation that the technology could render meaningless the Anti-Ballistic Missile (ABM) Treaty of 1972. The authors examine the ability of the political system to develop national strategies that incorporate the new realities created by technology.

  1. DIFFERENTIAL PROPER-MOTION STUDY OF THE CIRCUMSTELLAR DUST SHELL OF THE ENIGMATIC OBJECT, HD 179821

    SciTech Connect

    Ferguson, Brian A.; Ueta, Toshiya

    2010-03-10

    HD 179821 is an enigmatic evolved star that possesses characteristics of both a post-asymptotic giant branch (post-AGB) star and a yellow hypergiant, and there has been no evidence that unambiguously defines its nature. These two hypotheses are products of an indeterminate distance, presumed to be 1 kpc or 6 kpc. We have obtained the two-epoch Hubble Space Telescope Wild Field Planetary Camera 2 data of its circumstellar shell, which shows multiple concentric arcs extending out to about 8''. We have performed differential proper-motion measurements on distinct structures within the circumstellar shell of this mysterious star in hopes of determining the distance to the object, and thereby distinguishing the nature of this enigmatic stellar source. Upon investigation, rather than azimuthal radially symmetric expansion, we discovered a bulk motion of the circumstellar shell of (2.41 +- 0.43, 2.97 +- 0.32) mas yr{sup -1}. This corresponded to a translational interstellar medium (ISM) flow of (1.28 +- 0.95, 7.27 +- 0.75) mas yr{sup -1} local to the star. This finding implies that the distance to HD 179821 should be rather small in order for its circumstellar shell to preserve its highly intact spherical structure in the presence of the distorting ISM flow, therefore favoring the proposition that HD 179821 is a post-AGB object.

  2. What Should Be the Moral Aims of Compulsory Sex Education?

    ERIC Educational Resources Information Center

    Steutel, Jan; de Ruyter, Doret J.

    2011-01-01

    With reference to the unsuccessful attempt of the Labour Government to make sex education a statutory part of the National Curriculum, this paper argues in favour of making liberal sex education compulsory at all state schools. First, the main characteristics of a liberal sex education are briefly explained. Promoting the virtue of respect for…

  3. The Seeds of Artificial Intelligence. SUMEX-AIM.

    ERIC Educational Resources Information Center

    Research Resources Information Center, Rockville, MD.

    Written to provide an understanding of the broad base of information on which the artificial intelligence (AI) branch of computer science rests, this publication presents a general view of AI, the concepts from which it evolved, its current abilities, and its promise for research. The focus is on a community of projects that use the SUMEX-AIM…

  4. "Our Aim Is to Put Learners in the Driving Seat"

    ERIC Educational Resources Information Center

    Hayes, John

    2010-01-01

    When some people think of post-18 education, they only perceive real merit in the traditional university route. The central role that further education (FE) plays in the economy and society is often overlooked and undervalued. In truth, FE for adults, whether in a college, at work, or an informal evening class, not only has the power to improve…

  5. Ready, Fire, Aim: The College Campus Gun Fight

    ERIC Educational Resources Information Center

    Birnbaum, Robert

    2013-01-01

    The question of whether guns should be permitted on college and university campuses in the United States reflects the tension between two competing perspectives. America has both a robust gun culture and an equally robust (if less well known) gun-control culture. The gun culture is as American as apple pie: There may be as many as 300 million…

  6. A New Professional: The Aims of Education Revisited

    ERIC Educational Resources Information Center

    Palmer, Parker J.

    2007-01-01

    The word "professional" originally meant someone who makes a "profession of faith" in the midst of a disheartening world. That root meaning became diminished as the centuries rolled by, and today it has all but disappeared. "Professional" now means someone who possesses knowledge and techniques too esoteric for the laity to understand, whose…

  7. The Trouble with Outcomes: Pragmatic Inquiry and Educational Aims

    ERIC Educational Resources Information Center

    Gallagher, Chris W.

    2012-01-01

    Although outcomes assessment (OA) has become "common sense" in higher education, this article shows that the concept of "outcomes" tends to limit and compromise teaching and learning while serving the interests of institutional management. By contrast, the pragmatic concept of consequences tends to expand our view of teaching and learning, and…

  8. Aiming at the target: improved adjuvant medical therapy.

    PubMed

    Bedard, Philippe L; Dinh, Phuong; Sotiriou, Christos; Piccart-Gebhart, Martine J

    2009-10-01

    The 2007 St. Gallen Expert Panel recognized the existence of molecular tools for risk stratification, but recommended the use of high-quality standard pathological testing alone for risk allocation and treatment selection. Over the last two years, much has been learned about these novel molecular tools: they demonstrate similar prognostic power; their performance appears to be driven by improved quantification of cellular proliferation; tumour burden remains an important determinant of long-term outcome; and their prediction of responsiveness to systemic therapy is suboptimal. In the meantime, great effort has continued to be invested in evaluating individual predictive markers to guide treatment selection. A number of putative targets that showed early promise--such as HER-2 and TOP2A gene amplification for anthracyclines, Myc amplification for trastuzumab, and Tau expression for taxanes--have yielded disappointing results when subjected to subsequent validation. These failings underscore the difficulty of accurate, reproducible target measurement and the inherent complexity of early breast cancer which is unlikely to be captured by a single gene or protein alteration. Future progress in adjuvant treatment tailoring will require a fundamental shift towards multi-dimensional thinking--with the development of multi-parameter assays that integrate tumour biology, disease burden, and host-related factors. The traditional model of post hoc predictive marker validation appears unlikely to produce tangible gains in the era of targeted systemic therapy. It is hoped that coupling prospective biomarker discovery with new drug development in earlier stages of disease will yield additional targets that can be used to guide clinical decision-making in the future. PMID:19914538

  9. Aiming for benchmark accuracy with the many-body expansion.

    PubMed

    Richard, Ryan M; Lao, Ka Un; Herbert, John M

    2014-09-16

    Conspectus The past 15 years have witnessed an explosion of activity in the field of fragment-based quantum chemistry, whereby ab initio electronic structure calculations are performed on very large systems by decomposing them into a large number of relatively small subsystem calculations and then reassembling the subsystem data in order to approximate supersystem properties. Most of these methods are based, at some level, on the so-called many-body (or "n-body") expansion, which ultimately requires calculations on monomers, dimers, ..., n-mers of fragments. To the extent that a low-order n-body expansion can reproduce supersystem properties, such methods replace an intractable supersystem calculation with a large number of easily distributable subsystem calculations. This holds great promise for performing, for example, "gold standard" CCSD(T) calculations on large molecules, clusters, and condensed-phase systems. The literature is awash in a litany of fragment-based methods, each with their own working equations and terminology, which presents a formidable language barrier to the uninitiated reader. We have sought to unify these methods under a common formalism, by means of a generalized many-body expansion that provides a universal energy formula encompassing not only traditional n-body cluster expansions but also methods designed for macromolecules, in which the supersystem is decomposed into overlapping fragments. This formalism allows various fragment-based methods to be systematically classified, primarily according to how the fragments are constructed and how higher-order n-body interactions are approximated. This classification furthermore suggests systematic ways to improve the accuracy. Whereas n-body approaches have been thoroughly tested at low levels of theory in small noncovalent clusters, we have begun to explore the efficacy of these methods for large systems, with the goal of reproducing benchmark-quality calculations, ideally meaning complete

  10. Future technology aim of the National Aerospace Plane Program

    NASA Technical Reports Server (NTRS)

    Anderson, Charles W.

    1993-01-01

    Technical areas where hypersonic technology programs outside NASP might offer assistance and participate in the NASP program are considered. These specific areas include airframe, technology opportunities for providing better performance and reduced weight, the NDV application of NASP technology, and engine propellant systems and subsystems.

  11. Creating a Reconciliatory Discourse on the Diverse Aims of Education.

    ERIC Educational Resources Information Center

    LePage, Pamela; Sockett, Hugh

    This paper develops a moral approach to educational controversy, examining a collaborative research project that promotes reconciliation between diverse perspectives and laying out the foundations of a reconciliatory discourse. Section 1 discusses problems in education that contribute to unproductive discourse (conflict of educational purposes,…

  12. The Professionalization of Management: Aims, Obstacles, and Prospects

    ERIC Educational Resources Information Center

    Moskovskaia, A. A.

    2012-01-01

    Management in Russia is as difficult to define as a profession as it is in other countries, and the question of what education is appropriate for a future manager is also difficult to define. Business schools in Russia need to think more carefully about their curriculums and about what they should be preparing their students for. (Contains 6…

  13. The Relationship of Independent Study, Object Visualization, and Anxiety to Hypothesis Formation by College Freshmen in the Biological Sciences.

    ERIC Educational Resources Information Center

    Brown, Dorothy McKenna

    Reported is a study of the relationship of independent study, object visualization, and anxiety to hypothesis formation by college freshmen in the biological sciences. The participants of the study were 108 undergraduate females who had no previous science instruction and who were enrolled in introductory biology classes. The subjects, randomly…

  14. Achieving the prediction results by visualized treatment objective following anterior maxillary segmental osteotomy. A retrospective study.

    PubMed

    Venkatesh, V; Kumar, K A Jeevan; Mohan, A P; Kumar, B Pavan; Kunusoth, Ramesh; Kumar, M Pavan

    2013-06-01

    This study used the manual visualized treatment objectives (VTO) as a tool to evaluate the predictive value of the computer-assisted VTO. Presurgical cephalometric tracing predictions generated by oral and maxillofacial surgeons and computer-assisted VTOs were compared with the postsurgical outcome as seen on lateral cephalometric tracings. Ten measurements of the predicted and actual postsurgical hard tissue landmarks were compared statistically. A paired Student's t test showed that in nine of ten measurements, there were no statistically significant differences in the mean values of manual VTO (MVTO). Statistically significant differences were found in one of the four linear measurements (cant of upper lip P - 0.0001). For computer assisted (CAVTO) Student's t test showed that in nine of ten measurements, there were no statistically significant differences in the mean values. Statistically significant differences were found in one of the four linear measurements (nasolabial angle, P  - 0.0001). From these data, it appears that both VTOs demonstrated good predictive comparative outcome, and are equally predictive, but CAVTO is precise. PMID:24431838

  15. The Influence of Action Perception on Object Recognition: A Developmental Study

    ERIC Educational Resources Information Center

    Mounoud, Pierre; Duscherer, Katia; Moy, Guenael; Perraudin, Sandrine

    2007-01-01

    Two experiments explored the existence and the development of relations between action representations and object representations. A priming paradigm was used in which participants viewed an action pantomime followed by the picture of a tool, the tool being either associated or unassociated with the preceding action. Overall, we observed that the…

  16. Developing Values for Secondary School Students through the Study of Art Objects

    ERIC Educational Resources Information Center

    Dulama, Maria Eliza; Iovu, Mihai-Bogdan; Ursu, Alexandru Marius Bodochi

    2011-01-01

    The paper begins with some issues related to aesthetics, aesthetic education, art and axiological education. The empirical research has the general assumption that secondary school students and youth have difficulties in selecting values. The objective of the research was three fold: to design, to organize and to carry learning activities from…

  17. Satellite studies on the use of electric fields for shielding biological objects against cosmic rays.

    PubMed

    Kovalev, E E; Riabova, T Y

    1977-01-01

    The paper presents the results of measurements of conduction currents in strong electric fields of an electrostatic radiation shield apparatus aboard the Cosmos 690 artificial satellite. Power, dose and weight-size characteristics were calculated for an electrostatic shield and it was concluded that with available high-voltage technology it is possible to create an efficient low-weight electrostatic shield against cosmic radiation for biological objects. The development of an electric field system for in-flight radiation protection of biological objects could solve a number of other technological problems, such as protection of equipment and instruments against electric inductions, discharges and surface breakdowns. PMID:12596812

  18. The AIMS65 Score Is a Useful Predictor of Mortality in Patients with Nonvariceal Upper Gastrointestinal Bleeding: Urgent Endoscopy in Patients with High AIMS65 Scores

    PubMed Central

    Park, Sun Wook; Song, Young Wook; Tak, Dae Hyun; Ahn, Byung Moo; Kang, Sun Hyung; Moon, Hee Seok; Sung, Jae Kyu; Jeong, Hyun Yong

    2015-01-01

    Background/Aims: To validate the AIMS65 score for predicting mortality of patients with nonvariceal upper gastrointestinal bleeding and to evaluate the effectiveness of urgent (<8 hours) endoscopic procedures in patients with high AIMS65 scores. Methods: This was a 5-year single-center, retrospective study. Nonvariceal, upper gastrointestinal bleeding was assessed by using the AIM65 and Rockall scores. Scores for mortality were assessed by calculating the area under the receiver-operating characteristic curve (AUROC). Patients with high AIMS65 scores (≥2) were allocated to either the urgent or non-urgent endoscopic procedure group. In-hospital mortality, success of endoscopic procedure, recurrence of bleeding, admission period, and dose of transfusion were compared between groups. Results: A total of 634 patients were analyzed. The AIMS65 score successfully predicted mortality (AUROC=0.943; 95% confidence interval [CI], 0.876 to 0.99) and was superior to the Rockall score (AUROC=0.856; 95% CI, 0.743 to 0.969) in predicting mortality. The group with high AIMS65 score included 200 patients. The urgent endoscopic procedure group had reduced hospitalization periods (p<0.05) Conclusions: AIMS65 score may be useful in predicting mortality in patients with nonvariceal upper gastrointestinal bleeding. Urgent endoscopic procedures in patients with high scores may be related to reduced hospitalization periods. PMID:26668799

  19. Teaching Object Permanence: An Action Research Study

    ERIC Educational Resources Information Center

    Bruce, Susan M.; Vargas, Claudia

    2013-01-01

    "Object permanence," also known as "object concept" in the field of visual impairment, is one of the most important early developmental milestones. The achievement of object permanence is associated with the onset of representational thought and language. Object permanence is important to orientation, including the recognition of landmarks.…

  20. An ERP Study of the Processing of Subject and Object Relative Clauses in Japanese

    ERIC Educational Resources Information Center

    Ueno, Mieko; Garnsey, Susan M.

    2008-01-01

    Using reading times and event-related brain potentials (ERPs), we investigated the processing of Japanese subject and object relative clauses (SRs/ORs). Previous research on English relative clauses shows that ORs take longer to read (King & Just, 1991) and elicit anterior negativity between fillers and gaps (King & Kutas, 1995), which is…

  1. The HST Object Catalog

    NASA Astrophysics Data System (ADS)

    Lubow, Stephen H.; Budavari, T.

    2012-05-01

    We have created a catalog of objects observed by the WFPC2 and ACS instruments on the Hubble Space Telescope (HST). The catalog is based on observations taken on more than 6000 visits (telescope pointings) of ACS/WFC and more than 25000 visits of WFPC2. The catalog is obtained by cross-matching all Hubble Legacy Archive (HLA) Source Extractor source lists for these instruments. The source lists describe source detections within a visit. As a biproduct of the cross-matching, we obtain improved relative astrometry of the HST images. We apply a Bayesian method to help determine which source detections likely match. The catalog provides information about which source detections match together across visits. For each source detection, the catalog contains information that includes the corrected position, the name of the image, the filter, the exposure time, the exposure start and stop times, and the source magnitude. We also provide information on nondetections that can be used to determine dropouts. The catalog will be made publicly available.

  2. Spectroscopic and molecular modeling study on the separate and simultaneous bindings of alprazolam and fluoxetine hydrochloride to human serum albumin (HSA): With the aim of the drug interactions probing

    NASA Astrophysics Data System (ADS)

    Dangkoob, Faeze; Housaindokht, Mohmmad Reza; Asoodeh, Ahmad; Rajabi, Omid; Rouhbakhsh Zaeri, Zeinab; Verdian Doghaei, Asma

    2015-02-01

    The objective of the present research is to study the interaction of separate and simultaneous of alprazolam (ALP) and fluoxetine hydrochloride (FLX) with human serum albumin (HSA) in phosphate buffer (pH 7.4) using different kinds of spectroscopic, cyclic voltammetry and molecular modeling techniques. The absorbance spectra of protein, drugs and protein-drug showed complex formation between the drugs and HSA. Fluorescence analysis demonstrated that ALP and FLX could quench the fluorescence spectrum of HSA and demonstrated the conformational change of HSA in the presence of both drugs. Also, fluorescence quenching mechanism of HSA-drug complexes both separately and simultaneously was suggested as static quenching. The analysis of UV absorption data and the fluorescence quenching of HSA in the binary and ternary systems showed that FLX decreased the binding affinity between ALP and HSA. On the contrary, ALP increased the binding affinity of FLX and HSA. The results of synchronous fluorescence and three-dimensional fluorescence spectra indicated that the binding of drugs to HSA would modify the microenvironment around the Trp and Tyr residues and the conformation of HSA. The distances between Trp residue and the binding sites of the drugs were estimated according to the Förster theory, and it was demonstrated that non-radiative energy transfer from HSA to the drugs occurred with a high probability. Moreover, according to CV measurements, the decrease of peak current in the cyclic voltammogram of the both drugs in the presence of HSA revealed that they interacted with albumin and binding constants were calculated for binary systems which were in agreement with the binding constants obtained from UV absorption and fluorescence spectroscopy. The prediction of the best binding sites of ALP and FLX in binary and ternary systems in molecular modeling approach was done using of Gibbs free energy.

  3. Spectroscopic and molecular modeling study on the separate and simultaneous bindings of alprazolam and fluoxetine hydrochloride to human serum albumin (HSA): with the aim of the drug interactions probing.

    PubMed

    Dangkoob, Faeze; Housaindokht, Mohmmad Reza; Asoodeh, Ahmad; Rajabi, Omid; Rouhbakhsh Zaeri, Zeinab; Verdian Doghaei, Asma

    2015-02-25

    The objective of the present research is to study the interaction of separate and simultaneous of alprazolam (ALP) and fluoxetine hydrochloride (FLX) with human serum albumin (HSA) in phosphate buffer (pH 7.4) using different kinds of spectroscopic, cyclic voltammetry and molecular modeling techniques. The absorbance spectra of protein, drugs and protein-drug showed complex formation between the drugs and HSA. Fluorescence analysis demonstrated that ALP and FLX could quench the fluorescence spectrum of HSA and demonstrated the conformational change of HSA in the presence of both drugs. Also, fluorescence quenching mechanism of HSA-drug complexes both separately and simultaneously was suggested as static quenching. The analysis of UV absorption data and the fluorescence quenching of HSA in the binary and ternary systems showed that FLX decreased the binding affinity between ALP and HSA. On the contrary, ALP increased the binding affinity of FLX and HSA. The results of synchronous fluorescence and three-dimensional fluorescence spectra indicated that the binding of drugs to HSA would modify the microenvironment around the Trp and Tyr residues and the conformation of HSA. The distances between Trp residue and the binding sites of the drugs were estimated according to the Förster theory, and it was demonstrated that non-radiative energy transfer from HSA to the drugs occurred with a high probability. Moreover, according to CV measurements, the decrease of peak current in the cyclic voltammogram of the both drugs in the presence of HSA revealed that they interacted with albumin and binding constants were calculated for binary systems which were in agreement with the binding constants obtained from UV absorption and fluorescence spectroscopy. The prediction of the best binding sites of ALP and FLX in binary and ternary systems in molecular modeling approach was done using of Gibbs free energy. PMID:25300043

  4. Thermal Studies of Near Earth Objects

    NASA Technical Reports Server (NTRS)

    Jewitt, David

    2003-01-01

    In this proposal, we seek to apply the optical/thermal method to the measurement of the diameters and albedos of a large sample of Near Earth Objects (NEOs). Whereas main-belt asteroids have been studied in large numbers, principally using thermal detections from the IRAS satellite, relatively few thermal observations of NEOs have been secured. This program capitalizes on our access to large telescopes and imaging thermal IR detectors in pursuit of the definitive set of albedo data on the NEOs.

  5. Study of high-definition and stereoscopic head-aimed vision for improved teleoperation of an unmanned ground vehicle

    NASA Astrophysics Data System (ADS)

    Tyczka, Dale R.; Wright, Robert; Janiszewski, Brian; Chatten, Martha Jane; Bowen, Thomas A.; Skibba, Brian

    2012-06-01

    Nearly all explosive ordnance disposal robots in use today employ monoscopic standard-definition video cameras to relay live imagery from the robot to the operator. With this approach, operators must rely on shadows and other monoscopic depth cues in order to judge distances and object depths. Alternatively, they can contact an object with the robot's manipulator to determine its position, but that approach carries with it the risk of detonation from unintentionally disturbing the target or nearby objects. We recently completed a study in which high-definition (HD) and stereoscopic video cameras were used in addition to conventional standard-definition (SD) cameras in order to determine if higher resolutions and/or stereoscopic depth cues improve operators' overall performance of various unmanned ground vehicle (UGV) tasks. We also studied the effect that the different vision modes had on operator comfort. A total of six different head-aimed vision modes were used including normal-separation HD stereo, SD stereo, "micro" (reduced separation) SD stereo, HD mono, and SD mono (two types). In general, the study results support the expectation that higher resolution and stereoscopic vision aid UGV teleoperation, but the degree of improvement was found to depend on the specific task being performed; certain tasks derived notably more benefit from improved depth perception than others. This effort was sponsored by the Joint Ground Robotics Enterprise under Robotics Technology Consortium Agreement #69-200902 T01. Technical management was provided by the U.S. Air Force Research Laboratory's Robotics Research and Development Group at Tyndall AFB, Florida.

  6. The study on gear transmission multi-objective optimum design based on SQP algorithm

    NASA Astrophysics Data System (ADS)

    Li, Quancai; Qiao, Xuetao; Wu, Cuirong; Wang, Xingxing

    2011-12-01

    Gear mechanism is the most popular transmission mechanism; however, the traditional design method is complex and not accurate. Optimization design is the effective method to solve the above problems, used in gear design method. In many of the optimization software MATLAB, there are obvious advantage projects and numerical calculation. There is a single gear transmission as example, the mathematical model of gear transmission system, based on the analysis of the objective function, and on the basis of design variables and confirmation of choice restrictive conditions. The results show that the algorithm through MATLAB, the optimization designs, efficient, reliable, simple.

  7. The National Cancer Informatics Program (NCIP) Annotation and Image Markup (AIM) Foundation model.

    PubMed

    Mongkolwat, Pattanasak; Kleper, Vladimir; Talbot, Skip; Rubin, Daniel

    2014-12-01

    Knowledge contained within in vivo imaging annotated by human experts or computer programs is typically stored as unstructured text and separated from other associated information. The National Cancer Informatics Program (NCIP) Annotation and Image Markup (AIM) Foundation information model is an evolution of the National Institute of Health's (NIH) National Cancer Institute's (NCI) Cancer Bioinformatics Grid (caBIG®) AIM model. The model applies to various image types created by various techniques and disciplines. It has evolved in response to the feedback and changing demands from the imaging community at NCI. The foundation model serves as a base for other imaging disciplines that want to extend the type of information the model collects. The model captures physical entities and their characteristics, imaging observation entities and their characteristics, markups (two- and three-dimensional), AIM statements, calculations, image source, inferences, annotation role, task context or workflow, audit trail, AIM creator details, equipment used to create AIM instances, subject demographics, and adjudication observations. An AIM instance can be stored as a Digital Imaging and Communications in Medicine (DICOM) structured reporting (SR) object or Extensible Markup Language (XML) document for further processing and analysis. An AIM instance consists of one or more annotations and associated markups of a single finding along with other ancillary information in the AIM model. An annotation describes information about the meaning of pixel data in an image. A markup is a graphical drawing placed on the image that depicts a region of interest. This paper describes fundamental AIM concepts and how to use and extend AIM for various imaging disciplines. PMID:24934452

  8. A focus group study of the use of video-recorded simulated objective structured clinical examinations in nurse practitioner education.

    PubMed

    Barratt, Julian

    2010-05-01

    The objective structured clinical examination (OSCE) is a common method of clinical skills assessment used for advanced nurse practitioner students across the United Kingdom. The purpose of an advanced nursing OSCE is to assess a nurse practitioner student's competence and safety in the performance of commonly used advanced clinical practice skills. Students often feel nervous when preparing for and participating in an OSCE. Consideration of these identified anxieties led to the development of an alternative method of meeting students' OSCE learning and preparation needs; namely video-recorded simulated OSCEs. Video-recording was appealing for the following reasons: it provides a flexible usage of staff resources and time; OSCE performance mistakes can be rectified; it is possible to use the same video-recordings with multiple cohorts of students, and the recordings can be made conveniently available for students with video streaming on internet-based video-sharing sites or virtual learning environments. The aim of the study was to explore the value of using such recordings amongst nurse practitioner students, via online and face-to-face focus groups, to see if they are a suitable OSCE educational preparation technique. The study findings indicate that simulated OSCE video-recordings are an effective method for supporting nurse practitioner educational development. PMID:20202909

  9. The Effects of Age on Divergent Thinking and Creative Objects Production: A Cross-Sectional Study

    ERIC Educational Resources Information Center

    Massimiliano, Palmiero

    2015-01-01

    Age-related changes in divergent thinking and creative objects production were investigated in 150 native Italian speakers, divided into six age groups, each one comprised 25 participants: young (20-29), young adult (30-39), middle aged (40-49), adult-old (50-59), old (60-69), and old-old (70-80). Two tasks were used: the alternative uses task,…

  10. The Many Organisational Factors Relevant to Planning Change in Emergency Care Departments: A Qualitative Study to Inform a Cluster Randomised Controlled Trial Aiming to Improve the Management of Patients with Mild Traumatic Brain Injuries

    PubMed Central

    Bosch, Marije; Tavender, Emma J.; Brennan, Sue E.; Knott, Jonathan; Gruen, Russell L.; Green, Sally E.

    2016-01-01

    Background The Neurotrauma Evidence Translation (NET) Trial aims to design and evaluate the effectiveness of a targeted theory-and evidence-informed intervention to increase the uptake of evidence-based recommended practices for the management of patients who present to an emergency department (ED) with mild head injuries. When designing interventions to bring about change in organisational settings such as the ED, it is important to understand the impact of the context to ensure successful implementation of practice change. Few studies explicitly use organisational theory to study which factors are likely to be most important to address when planning change processes in the ED. Yet, this setting may have a unique set of organisational pressures that need to be taken into account when implementing new clinical practices. This paper aims to provide an in depth analysis of the organisational context in which ED management of mild head injuries and implementation of new practices occurs, drawing upon organisational level theory. Methods Semi-structured interviews were conducted with ED staff in Australia. The interviews explored the organisational context in relation to change and organisational factors influencing the management of patients presenting with mild head injuries. Two researchers coded the interview transcripts using thematic content analysis. The “model of diffusion in service organisations” was used to guide analyses and organisation of the results. Results Nine directors, 20 doctors and 13 nurses of 13 hospitals were interviewed. With regard to characteristics of the innovation (i.e. the recommended practices) the most important factor was whether they were perceived as being in line with values and needs. Tension for change (the degree to which stakeholders perceive the current situation as intolerable or needing change) was relatively low for managing acute mild head injury symptoms, and mixed for managing longer-term symptoms (higher change

  11. Objectively Measured Physical Activity in European Adults: Cross-Sectional Findings from the Food4Me Study

    PubMed Central

    Marsaux, Cyril F. M.; Celis-Morales, Carlos; Hoonhout, Jettie; Claassen, Arjan; Goris, Annelies; Forster, Hannah; Fallaize, Rosalind; Macready, Anna L.; Navas-Carretero, Santiago; Kolossa, Silvia; Walsh, Marianne C.; Lambrinou, Christina-Paulina; Manios, Yannis; Godlewska, Magdalena; Traczyk, Iwona; Lovegrove, Julie A.; Martinez, J. Alfredo; Daniel, Hannelore; Gibney, Mike; Mathers, John C.; Saris, Wim H. M.

    2016-01-01

    Background Comparisons of objectively measured physical activity (PA) between residents of European countries measured concurrently with the same protocol are lacking. We aimed to compare PA between the seven European countries involved in the Food4Me Study, using accelerometer data collected remotely via the Internet. Methods Of the 1607 participants recruited, 1287 (539 men and 748 women) provided at least 3 weekdays and 2 weekend days of valid accelerometer data (TracmorD) at baseline and were included in the present analyses. Results Men were significantly more active than women (physical activity level = 1.74 vs. 1.70, p < 0.001). Time spent in light PA and moderate PA differed significantly between countries but only for women. Adherence to the World Health Organization recommendation to accumulate at least 150 min of moderate-equivalent PA weekly was similar between countries for men (range: 54–65%) but differed significantly between countries for women (range: 26–49%). Prevalence estimates decreased substantially for men and women in all seven countries when PA guidelines were defined as achieving 30 min of moderate and vigorous PA per day. Conclusions We were able to obtain valid accelerometer data in real time via the Internet from 80% of participants. Although our estimates are higher compared with data from Sweden, Norway, Portugal and the US, there is room for improvement in PA for all countries involved in the Food4Me Study. PMID:26999053

  12. The IRYSS-COPD appropriateness study: objectives, methodology, and description of the prospective cohort

    PubMed Central

    2011-01-01

    Background Patients with chronic obstructive pulmonary disease (COPD) often experience exacerbations of the disease that require hospitalization. Current guidelines offer little guidance for identifying patients whose clinical situation is appropriate for admission to the hospital, and properly developed and validated severity scores for COPD exacerbations are lacking. To address these important gaps in clinical care, we created the IRYSS-COPD Appropriateness Study. Methods/Design The RAND/UCLA Appropriateness Methodology was used to identify appropriate and inappropriate scenarios for hospital admission for patients experiencing COPD exacerbations. These scenarios were then applied to a prospective cohort of patients attending the emergency departments (ED) of 16 participating hospitals. Information was recorded during the time the patient was evaluated in the ED, at the time a decision was made to admit the patient to the hospital or discharge home, and during follow-up after admission or discharge home. While complete data were generally available at the time of ED admission, data were often missing at the time of decision making. Predefined assumptions were used to impute much of the missing data. Discussion The IRYSS-COPD Appropriateness Study will validate the appropriateness criteria developed by the RAND/UCLA Appropriateness Methodology and thus better delineate the requirements for admission or discharge of patients experiencing exacerbations of COPD. The study will also provide a better understanding of the determinants of outcomes of COPD exacerbations, and evaluate the equity and variability in access and outcomes in these patients. PMID:22115318

  13. The Autism Impact Measure (AIM): Initial Development of a New Tool for Treatment Outcome Measurement

    ERIC Educational Resources Information Center

    Kanne, Stephen M.; Mazurek, Micah O.; Sikora, Darryn; Bellando, Jayne; Branum-Martin, Lee; Handen, Benjamin; Katz, Terry; Freedman, Brian; Powell, Mary Paige; Warren, Zachary

    2014-01-01

    The current study describes the development and psychometric properties of a new measure targeting sensitivity to change of core autism spectrum disorder (ASD) symptoms, the Autism Impact Measure (AIM). The AIM uses a 2-week recall period with items rated on two corresponding 5-point scales (frequency and impact). Psychometric properties were…

  14. The WellingTONNE Challenge Toolkit: Using the RE-AIM Framework to Evaluate a Community Resource Promoting Healthy Lifestyle Behaviours

    ERIC Educational Resources Information Center

    Caperchione, Cristina; Coulson, Fiona

    2010-01-01

    Objective: The RE-AIM framework has been recognized as a tool to evaluate the adoption, delivery, and sustainability of an intervention, and estimate its potential public health impact. In this study four dimensions of the RE-AIM framework (adoption, implementation, effectiveness, and maintenance) were used to evaluate the WellingTONNE Challenge…

  15. A Study of the Objectives for the Theological Preparation of Lutheran Church Missouri Synod Elementary Teachers

    ERIC Educational Resources Information Center

    Rockrohr, Deborah L.

    2013-01-01

    This study examined current practice in the area of theological preparation for Lutheran elementary teachers of the Lutheran Church-Missouri Synod (LCMS). As a church body with a well-defined doctrine, the LCMS requires a particular preparation for all ordained and commissioned workers placed on its official roster. A historical review of archival…

  16. The Netherlands XTC Toxicity (NeXT) study: objectives and methods of a study investigating causality, course, and clinical relevance.

    PubMed

    De Win, Maartje M L; Jager, Gerry; Vervaeke, Hylke K E; Schilt, Thelma; Reneman, Liesbeth; Booij, Jan; Verhulst, Frank C; Den Heeten, Gerard J; Ramsey, Nick F; Korf, Dirk J; Van den Brink, Wim

    2005-01-01

    This paper describes the objectives and methods of The Netherlands XTC Toxicity (NeXT) study focussing on the causality, course, and clinical relevance of ecstasy neurotoxicity. Previous studies suggest that ecstasy (3,4 methylene-dioxymethamphetamine, MDMA, XTC) is toxic toward brain serotonin axons, but most of these studies have serious methodological limitations. The current study is a combination of different approaches with three substudies: (1) a crosssectional substudy among heavy ecstasy users and controls with variation in drug use, which will provide information about potential neurotoxic consequences of ecstasy in relation to other drugs; (2) a prospective cohort substudy in ecstasy-naive subjects with high risk for future ecstasy use, which will provide information on the causality and short-term course of ecstasy use and potential neurotoxicity, and (3) a retrospective cohort substudy in lifetime ecstasy users and matched controls of an existing epidemiological sample that will provide information on long-term course and outcome of ecstasy use in the general population. Neurotoxicity is studied using (a) different imaging techniques (beta-CIT SPECT, 1H-MR spectroscopy, diffusion tensor imaging, perfusion weighted imaging and functional magnetic resonance imaging), and (b) neuropsychological and psychiatric assessments of memory, depression, and personality. The combined results will lead to conclusions that can be used in prevention messages, clinical decision making, and the development of an (inter)national ecstasy policy. PMID:16395871

  17. Long-term study of water maser emission associated with young stellar objects. I. The database

    NASA Astrophysics Data System (ADS)

    Valdettaro, R.; Palla, F.; Brand, J.; Cesaroni, R.; Comoretto, G.; Felli, M.; Palagi, F.

    2002-01-01

    We present the results of more than 10 years of monitoring of the water vapor maser emission in 14 star forming regions obtained with the Medicina 32-m radiotelescope. The sample of objects covers a large range of luminosities of the associated FIR sources. In order to present in a compact and representative way the large amount of data available, we give for each source: a time-velocity-flux density plot, the time dependent integrated flux, the lower and upper envelopes of the maser emission, the frequency of the maser occurrence as a function of velocity, and the mean velocity averaged over the observing period. A brief morphological description of the environment of the maser source is also given. The present data form the basis for a discussion of the main properties of the water vapor maser emission to be presented in a forthcoming paper.

  18. The Intervening Galaxies Hypothesis of the Absorption Spectra of Quasi-Stellar Objects: Some Statistical Studies

    NASA Astrophysics Data System (ADS)

    Duari, Debiprosad; Narlikar, Jayant V.

    This paper examines, in the light of the available data, the hypothesis that the heavy element absorption line systems in the spectra of QSOs originate through en-route absorption by intervening galaxies, halos etc. Several statistical tests are applied in two different ways to compare the predictions of the intervening galaxies hypothesis (IGH) with actual observations. The database is taken from a recent 1991 compilation of absorption line systems by Junkkarinen, Hewitt and Burbidge. Although, prima facie, a considerable gap is found between the predictions of the intervening galaxies hypothesis and the actual observations despite inclusion of any effects of clustering and some likely selection effects, the gap narrows after invoking evolution in the number density of absorbers and allowing for the incompleteness and inhomogeneity of samples examined. On the latter count the gap might be bridgeable by stretching the parameters of the theory. It is concluded that although the intervening galaxies hypothesis is a possible natural explanation to account for the absorption line systems and may in fact do so in several cases, it seems too simplistic to be able to account for all the available data. It is further stressed that the statistical techniques described here will be useful for future studies of complete and homogenous samples with a view to deciding the extent of applicability of the IGH.

  19. Practical Study on HVAC Control Technology Based on the Learning Function and Optimum Multiple Objective Processes

    NASA Astrophysics Data System (ADS)

    Ueda, Haruka; Dazai, Ryota; Kaseda, Chosei; Ikaga, Toshiharu; Kato, Akihiro

    Demand among large office buildings for the energy-saving benefits of the HVAC (Heating, Ventilating and Air-Conditioning) System are increasing as more and more people become concerned with global environmental issues. However, immoderate measures taken in the interest of energy conservation may encroach on the thermal comfort and productivity level of office workers. Building management should satisfy both indoor thermal comfort and energy conservation while adapting to the many regulatory, social, climate, and other changes that occur during the lifespan of the building. This paper demonstrates how optimal control of the HVAC system, based on data modeling and the multi-objective optimal method, achieves an efficient equilibrium between thermal comfort and energy conservation.

  20. Objective measures of Physical Activity, Fractures and Falls: The Osteoporotic Fractures in Men Study (MrOS)

    PubMed Central

    Cauley, Jane A.; Harrison, Stephanie L.; Cawthon, Peggy M.; Ensrud, Kristine E.; Danielson, Michelle E.; Orwoll, Eric; Mackey, Dawn C.

    2013-01-01

    Background/Objectives Self-reported physical activity (PA) has been linked to lower hip fracture and fall rates. The objective of this study was to determine the association between objectively measured PA, fractures and falls. Design/Setting/Participants 2731 men (mean age 79 yrs) recruited at 6 US clinical sites into a longitudinal cohort study. Measurements Total and active energy expenditure (EE) and minutes per day spent in sedentary and moderate intensity activities were measured using the multi-sensor SenseWear Pro Armband (SWA)for at least 5 days. Energy expended at a metabolic equivalent (MET >3) was termed active EE. Incident non-spine fractures and falls were identified every 4 months. Results 759 (28.2%) men fell at least once over 12 months of follow-up; 186 (6.8%) men experienced ≥1 fracture over an average follow-up of 3.5± 0.9 years.The association between PA and falling varied by age (p interaction=0.02). Men the lowest active EE had a lower risk of falling (relative risk (RR) =0.75; p trend = 0.08)while men >80 yrs, with the lowest active EE had a higher risk of falling, RR=1.43, p trend=0.09. In multivariate models including health status, men in the lowest quintile of active EE had a significantly higher risk of fracture, hazard ratio (HR)=1.82 (95% confidence interval (CI) 1.10, 3.00), p trend=0.04. Men with less than 33 minutes/day of moderate activity had a 70% increased risk of fracture, HR=1.70(95% CI, 1.03, 2.80). Conclusion Age modifies the association between PA and falling. Interventions aimed at >30 minutes of moderate PA per day may reduce fracturesextending existing PA guidelines to the oldest old, the fastest growing proportion of those over age 65. PMID:23855842

  1. Geometry as Objective Science in Elementary School Classrooms: Mathematics in the Flesh. Routledge International Studies in the Philosophy of Education

    ERIC Educational Resources Information Center

    Roth, Wolff-Michael

    2011-01-01

    This study examines the origins of geometry in and out of the intuitively given everyday lifeworlds of children in a second-grade mathematics class. These lifeworlds, though pre-geometric, are not without model objects that denote and come to anchor geometric idealities that they will understand at later points in their lives. Roth's analyses…

  2. An ERP Study on Self-Relevant Object Recognition

    ERIC Educational Resources Information Center

    Miyakoshi, Makoto; Nomura, Michio; Ohira, Hideki

    2007-01-01

    We performed an event-related potential study to investigate the self-relevance effect in object recognition. Three stimulus categories were prepared: SELF (participant's own objects), FAMILIAR (disposable and public objects, defined as objects with less-self-relevant familiarity), and UNFAMILIAR (others' objects). The participants' task was to…

  3. Atlas of the Messier Objects

    NASA Astrophysics Data System (ADS)

    Stoyan, Ronald; Binnewies, Stefan; Friedrich, Susanne; Schroeder, Klaus-Peter

    2008-11-01

    Preface; How to use this book; The life of Charles Messier; The observations of Charles Messier; The catalog of Charles Messier; Statistics of the Messier objects; Observation of the Messier objects; Photography of the Messier objects; The objects themselves; Glossary; List of figures; Table of sources.

  4. AIMS Library - A community resource for sorghum genomic studies and breeding

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The sorghum genome sequence is completed. A systematically mutagenized population linking gene function to sequence is becoming increasingly urgent. A project was initiated to develop an Annotated Individually-pedigreed Mutagenized Sorghum (AIMS) library using (EMS) ethyl methane sulfonate for sel...

  5. Revitalising the Metropolit 1953 Danish male birth cohort: background, aims and design.

    PubMed

    Osler, Merete; Andersen, Anne-Marie Nybo; Lund, Rikke; Batty, G David; Hougaard, Charlotte Ørsted; Damsgaard, Mogens Trab; Due, Pernille; Holstein, Bjørn E

    2004-09-01

    Recent research indicates that factors operating during childhood are related to adult health. Thus, longitudinal studies with information on subsequent phases may be key to understanding later health outcomes. The main objective of this paper is to describe the history and design of a Danish birth cohort, and its revitalisation. In 1965, information from birth certificates for 11 591 of a total of 12 270 males born in 1953 in the Metropolitan area of Copenhagen, Denmark were traced. These boys were the study population of a sociological investigation conducted with the aim of describing social mobility. At age 12 years, 9537 of these cohort members completed a questionnaire in school, which included cognitive measures and information on social aspirations and leisure time activities. In 1966 educational performance tests were administered for these boys and, in 1968, mothers of 2890 cohort members were interviewed regarding family social backgrounds. With the establishment of the Civil Registration System (CRS) in 1968, it was possible to identify 11 532 cohort members. In 2002 we began the process of revitalising this study with the aim of investigating the influence of early life factors on later health. We succeeded in ascertaining the vital status of all subjects in the CRS. This showed that 863 subjects had died between 1968 and 2002. Linkages to the Register of Causes of Death, the National Hospital Register, Psychiatric Central Register and Danish Cancer Registry have been completed. In total, 7969 cohort members had been hospitalised for any somatic illness and, according to the Psychiatric Central Register, 1382 men had been admitted to a psychiatric hospital or ward. In the Cancer Registry we found 363 of our study participants. Analyses exploring the influence of social conditions in early life, birth dimensions, and childhood cognition on adult health experience are at various stages of completion. A questionnaire-based postal follow-up survey is

  6. Social Studies Objectives, Second Assessment. National Assessment of Educational Progress.

    ERIC Educational Resources Information Center

    Education Commission of the States, Denver, CO. National Assessment of Educational Progress.

    Major social studies objectives delineated in this booklet provide a framework for the measurement of student achievement in the social studies. The booklet is arranged in four chapters. The first chapter describes the development of social studies objectives; the other chapters respectively list the social studies objectives for the specific age…

  7. Optical and Near Infrared Study of the Cepheus E Outflow, a Very Low Excitation Object

    NASA Technical Reports Server (NTRS)

    Noreiga-Crespo, A.; Ayala, S.; Garnavich, P.; Curiel, S.; Raga, A.; Bohm, K.; Raymond, J.

    2000-01-01

    In this study, we explore the link between the physical properties of the outflow as determined from optical imaging and spectroscopy, and compare these results with those obtained from observations in the near infrared.

  8. The Implementation and Development of an Objective Structured Clinical Examination in the Community Pharmacy Course of a Select Gulf-Region Academic Institution (Ras Al Khaimah College of Pharmaceutical Sciences): A Pilot Study

    ERIC Educational Resources Information Center

    Al-Azzawi, Amad Mohammed Jamil; Nagavi, B.G.; Hachim, Mahmood Y.; Mossa, Omar H.

    2016-01-01

    Background: Objective Structured Clinical Examinations (OSCEs) were used to assess translational pharmacotherapeutic skills of a Gulf-region representative academic institution. Aim: The aim of the current study was to assess the clinical skills of students enrolled within the third year Bachelor of Pharmacy (BPharm) programme within Ras Al…

  9. Chicago Healthy Aging Study: Objectives and Design

    PubMed Central

    Pirzada, Amber; Reid, Kathryn; Kim, Daniel; Garside, Daniel B.; Lu, Brandon; Vu, Thanh-Huyen T.; Lloyd-Jones, Donald M.; Zee, Phyllis; Liu, Kiang; Stamler, Jeremiah; Daviglus, Martha L.

    2013-01-01

    Investigators in the Chicago Healthy Aging Study (CHAS) reexamined 1,395 surviving participants aged 65–84 years (28% women) from the Chicago Heart Association Detection Project in Industry (CHA) 1967–1973 cohort whose cardiovascular disease (CVD) risk profiles were originally ascertained at ages 25–44 years. CHAS investigators reexamined 421 participants who were low-risk (LR) at baseline and 974 participants who were non-LR at baseline. LR was defined as having favorable levels of 4 major CVD risk factors: serum total cholesterol level <200 mg/dL and no use of cholesterol-lowering medication; blood pressure 120/≤80 mm Hg and no use of antihypertensive medication; no current smoking; and no history of diabetes or heart attack. While the potential of LR status in overcoming the CVD epidemic is being recognized, the long-term association of LR with objectively measured health in older age has not been examined. It is hypothesized that persons who were LR in 1967–1973 and have survived to older age will have less clinical and subclinical CVD, lower levels of inflammatory markers, and better physical performance/functioning and sleep quality. Here we describe the rationale, objectives, design, and implementation of this longitudinal epidemiologic study, compare baseline and follow-up characteristics of participants and nonparticipants, and highlight the feasibility of reexamining study participants after an extended period postbaseline with minimal interim contact. PMID:23669655

  10. Anticipatory care planning and integration: a primary care pilot study aimed at reducing unplanned hospitalisation

    PubMed Central

    Baker, Adrian; Leak, Paul; Ritchie, Lewis D; Lee, Amanda J; Fielding, Shona

    2012-01-01

    Background Anticipatory care for older patients who are frail involves both case identification and proactive intervention to reduce hospitalisation. Aim To identify a population who were at risk of admission to hospital and to provide an anticipatory care plan (ACP) for them and to ascertain whether using primary and secondary care data to identify this population and then applying an ACP can help to reduce hospital admission rates. Design and setting Cohort study of a service intervention in a general practice and a primary care team in Scotland. Method The ACP sets out patients’ wishes in the event of a sudden deterioration in health. If admitted, a proactive approach was taken to transfer and discharge patients into the community. Cohorts were selected using the Nairn Case Finder, which matched patients in two practices for age, sex, multiple morbidity indexes, and secondary care outpatient and inpatient activity; 96 patients in each practice were studied for admission rate, occupied bed days and survival. Results Survivors from the ACP cohort (n = 80) had 510 fewer days in hospital than in the 12 months pre-intervention: a significant reduction of 52.0% (P = 0.020). There were 37 fewer admissions of the survivors from that cohort post-intervention than in the preceding 12 months, with a significant reduction of 42.5% (P = 0.002). Mortality rates in the two cohorts were similar, but the number of patients who died in hospital and the hospital bed days used in the last 3 months of life were significantly lower for the decedents with an ACP than for the controls who had died (P = 0.007 and P = 0.045 respectively). Conclusion This approach produced statistically significant reductions in unplanned hospitalisation for a cohort of patients with multiple morbidities. It demonstrates the potential for providing better care for patients as well as better value for health and social care services. It is of particular benefit in managing end-of-life care. PMID:22520788

  11. A multi-wavelength interferometric study of the massive young stellar object IRAS 13481-6124

    NASA Astrophysics Data System (ADS)

    Boley, Paul A.; Kraus, Stefan; de Wit, Willem-Jan; Linz, Hendrik; van Boekel, Roy; Henning, Thomas; Lacour, Sylvestre; Monnier, John D.; Stecklum, Bringfried; Tuthill, Peter G.

    2016-02-01

    We present new mid-infrared interferometric observations of the massive young stellar object IRAS 13481-6124, using VLTI/MIDI for spectrally-resolved, long-baseline measurements (projected baselines up to ~120 m) and GSO/T-ReCS for aperture-masking interferometry in five narrow-band filters (projected baselines of ~1.8-6.4 m) in the wavelength range of 7.5-13μm. We combine these measurements with previously-published interferometric observations in the K and N bands in order to assemble the largest collection of infrared interferometric observations for a massive YSO to date. Using a combination of geometric and radiative-transfer models, we confirm the detection at mid-infrared wavelengths of the disk previously inferred from near-infrared observations. We show that the outflow cavity is also detected at both near- and mid-infrared wavelengths, and in fact dominates the mid-infrared emission in terms of total flux. For the disk, we derive the inner radius (~1.8 mas or ~6.5 AU at 3.6 kpc), temperature at the inner rim (~1760 K), inclination (~48°) and position angle (~107°). We determine that the mass of the disk cannot be constrained without high-resolution observations in the (sub-)millimeter regime or observations of the disk kinematics, and could be anywhere from ~10-3 to 20M⊙. Finally, we discuss the prospects of interpreting the spectral energy distributions of deeply-embedded massive YSOs, and warn against attempting to infer disk properties from the spectral energy distribution. Based in part on observations with the Very Large Telescope Interferometer of the European Southern Observatory, under program IDs 384.C-0625, 086.C-0543, 091.C-0357.

  12. A Study of the Questioning Behavior of Teachers in the Science Curriculum Improvement Study Teaching the Unit on Material Objects.

    ERIC Educational Resources Information Center

    Kondo, Allan Kiichi

    The Science Curriculum Improvement Study has identified two main types of lessons: invention lessons, where the teachers introduce concepts, and discovery lessons in which children apply the concepts to new situations. The transcripts of tape recordings of the same sequence of four lessons, two invention and two discovery, of four teachers in the…

  13. The healthy building intervention study: Objectives, methods and results of selected environmental measurements

    SciTech Connect

    Fisk, W.J.; Faulkner, D.; Sullivan, D.

    1998-02-17

    To test proposed methods for reducing SBS symptoms and to learn about the causes of these symptoms, a double-blind controlled intervention study was designed and implemented. This study utilized two different interventions designed to reduce occupants` exposures to airborne particles: (1) high efficiency filters in the building`s HVAC systems; and (2) thorough cleaning of carpeted floors and fabric-covered chairs with an unusually powerful vacuum cleaner. The study population was the workers on the second and fourth floors of a large office building with mechanical ventilation, air conditioning, and sealed windows. Interventions were implemented on one floor while the occupants on the other floor served as a control group. For the enhanced-filtration intervention, a multiple crossover design was used (a crossover is a repeat of the experiment with the former experimental group as the control group and vice versa). Demographic and health symptom data were collected via an initial questionnaire on the first study week and health symptom data were obtained each week, for eight additional weeks, via weekly questionnaires. A large number of indoor environmental parameters were measured during the study including air temperatures and humidities, carbon dioxide concentrations, particle concentrations, concentrations of several airborne bioaerosols, and concentrations of several microbiologic compounds within the dust sampled from floors and chairs. This report describes the study methods and summarizes the results of selected environmental measurements.

  14. Finding the object'' proceedings addendum

    SciTech Connect

    Whiting, M.A.; Devaney, D.M.

    1990-10-01

    The purpose of this workshop was to discuss finding the object -- that is, how software engineers imagine, invent, design, or recycle objects and their behaviors for object-oriented software engineering. The workshop organizers (and, as we subsequently discovered, several of the workshop participants) felt that this issue is crucial to successful object-oriented software engineering (after all, finding objects is what the projects is all about, isn't it ). Unfortunately, when previous workshops have had the opportunity to review and discuss techniques practitioners use to find objects, too often the results were heated debates on what is an object '' which becomes all consuming. We believed that, given appropriate control over the question of which kind of object'' is being discussed (which meant tell us what object you are trying to find, then tell us your method), a workshop to concentrate on techniques for finding objects would be quite appropriate. 8 refs., 2 figs.

  15. Lung-protective ventilation initiated in the emergency department (LOV-ED): a study protocol for a quasi-experimental, before-after trial aimed at reducing pulmonary complications

    PubMed Central

    Fuller, Brian M; Ferguson, Ian; Mohr, Nicholas M; Stephens, Robert J; Briscoe, Cristopher C; Kolomiets, Angelina A; Hotchkiss, Richard S; Kollef, Marin H

    2016-01-01

    Introduction In critically ill patients, acute respiratory distress syndrome (ARDS) and ventilator-associated conditions (VACs) are associated with increased mortality, survivor morbidity and healthcare resource utilisation. Studies conclusively demonstrate that initial ventilator settings in patients with ARDS, and at risk for it, impact outcome. No studies have been conducted in the emergency department (ED) to determine if lung-protective ventilation in patients at risk for ARDS can reduce its incidence. Since the ED is the entry point to the intensive care unit for hundreds of thousands of mechanically ventilated patients annually in the USA, this represents a knowledge gap in this arena. A lung-protective ventilation strategy was instituted in our ED in 2014. It aims to address the parameters in need of quality improvement, as demonstrated by our previous research: (1) prevention of volutrauma; (2) appropriate positive end-expiratory pressure setting; (3) prevention of hyperoxia; and (4) aspiration precautions. Methods and analysis The lung-protective ventilation initiated in the emergency department (LOV-ED) trial is a single-centre, quasi-experimental before-after study testing the hypothesis that lung-protective ventilation, initiated in the ED, is associated with reduced pulmonary complications. An intervention cohort of 513 mechanically ventilated adult ED patients will be compared with over 1000 preintervention control patients. The primary outcome is a composite outcome of pulmonary complications after admission (ARDS and VACs). Multivariable logistic regression with propensity score adjustment will test the hypothesis that ED lung-protective ventilation decreases the incidence of pulmonary complications. Ethics and dissemination Approval of the study was obtained prior to data collection on the first patient. As the study is a before-after observational study, examining the effect of treatment changes over time, it is being conducted with waiver of

  16. The Swedish CArdioPulmonary BioImage Study: objectives and design.

    PubMed

    Bergström, G; Berglund, G; Blomberg, A; Brandberg, J; Engström, G; Engvall, J; Eriksson, M; de Faire, U; Flinck, A; Hansson, M G; Hedblad, B; Hjelmgren, O; Janson, C; Jernberg, T; Johnsson, Å; Johansson, L; Lind, L; Löfdahl, C-G; Melander, O; Östgren, C J; Persson, A; Persson, M; Sandström, A; Schmidt, C; Söderberg, S; Sundström, J; Toren, K; Waldenström, A; Wedel, H; Vikgren, J; Fagerberg, B; Rosengren, A

    2015-12-01

    Cardiopulmonary diseases are major causes of death worldwide, but currently recommended strategies for diagnosis and prevention may be outdated because of recent changes in risk factor patterns. The Swedish CArdioPulmonarybioImage Study (SCAPIS) combines the use of new imaging technologies, advances in large-scale 'omics' and epidemiological analyses to extensively characterize a Swedish cohort of 30 000 men and women aged between 50 and 64 years. The information obtained will be used to improve risk prediction of cardiopulmonary diseases and optimize the ability to study disease mechanisms. A comprehensive pilot study in 1111 individuals, which was completed in 2012, demonstrated the feasibility and financial and ethical consequences of SCAPIS. Recruitment to the national, multicentre study has recently started. PMID:26096600

  17. Interventions aimed at improving the nursing work environment: a systematic review

    PubMed Central

    2010-01-01

    Background Nursing work environments (NWEs) in Canada and other Western countries have increasingly received attention following years of restructuring and reported high workloads, high absenteeism, and shortages of nursing staff. Despite numerous efforts to improve NWEs, little is known about the effectiveness of interventions to improve NWEs. The aim of this study was to review systematically the scientific literature on implemented interventions aimed at improving the NWE and their effectiveness. Methods An online search of the databases CINAHL, Medline, Scopus, ABI, Academic Search Complete, HEALTHstar, ERIC, Psychinfo, and Embase, and a manual search of Emerald and Longwoods was conducted. (Quasi-) experimental studies with pre/post measures of interventions aimed at improving the NWE, study populations of nurses, and quantitative outcome measures of the nursing work environment were required for inclusion. Each study was assessed for methodological strength using a quality assessment and validity tool for intervention studies. A taxonomy of NWE characteristics was developed that would allow us to identify on which part of the NWE an intervention targeted for improvement, after which the effects of the interventions were examined. Results Over 9,000 titles and abstracts were screened. Eleven controlled intervention studies met the inclusion criteria, of which eight used a quasi-experimental design and three an experimental design. In total, nine different interventions were reported in the included studies. The most effective interventions at improving the NWE were: primary nursing (two studies), the educational toolbox (one study), the individualized care and clinical supervision (one study), and the violence prevention intervention (one study). Conclusions Little is known about the effectiveness of interventions aimed at improving the NWE, and published studies on this topic show weaknesses in their design. To advance the field, we recommend that

  18. A Case Study Objectively Assessing Female Physical Activity Levels within the National Curriculum for Physical Education

    ERIC Educational Resources Information Center

    Hobbs, Matthew; Daly-Smith, Andrew; Morley, David; McKenna, James

    2015-01-01

    The purpose of this study was to assess the impact of the National Curriculum for Physical Education (NCPE) lesson themes and contexts on the profile of moderate-to-vigorous physical activity (MVPA). Fifteen, Year 9 Physical Education (PE) lessons were assessed within the lesson themes of Outwitting Opponents (OO) (delivered through field hockey…

  19. The Development of the Learning Object Standard Using a Pedagogic Approach: A Comparative Study.

    ERIC Educational Resources Information Center

    Yahya, Yazrina; Jenkins, John; Yusoff, Mohammed

    Education is moving towards revenue generation from such channels as electronic learning, distance learning and virtual education. Hence learning technology standards are critical to the sector's success. Existing learning technology standards have focused on various topics such as metadata, question and test interoperability and others. However,…

  20. Artworks as dichotomous objects: implications for the scientific study of aesthetic experience

    PubMed Central

    Pepperell, Robert

    2015-01-01

    This paper addresses an issue that has been studied from both scientific and art theoretical perspectives, namely the dichotomous nature of representational artworks. Representational artworks are dichotomous in that they present us with two distinct aspects at once. In one aspect we are aware of what is represented while in the other we are aware of the material from which the representation is composed. The dichotomy arises due the incompatibility, indeed contradiction, between these aspects of awareness, both of which must be present if we are to fully appreciate the artwork. Examples from art history are given to show how artists have exploited this dichotomy in a way that conditions our response to their work. I hypothesize that the degree of manifest dichotomy in a work determines the strength of its aesthetic effect, and propose this could be experimentally tested. I conclude that scientific studies of aesthetic experience should take the dichotomous nature of artworks into account. PMID:26106312

  1. Artworks as dichotomous objects: implications for the scientific study of aesthetic experience.

    PubMed

    Pepperell, Robert

    2015-01-01

    This paper addresses an issue that has been studied from both scientific and art theoretical perspectives, namely the dichotomous nature of representational artworks. Representational artworks are dichotomous in that they present us with two distinct aspects at once. In one aspect we are aware of what is represented while in the other we are aware of the material from which the representation is composed. The dichotomy arises due the incompatibility, indeed contradiction, between these aspects of awareness, both of which must be present if we are to fully appreciate the artwork. Examples from art history are given to show how artists have exploited this dichotomy in a way that conditions our response to their work. I hypothesize that the degree of manifest dichotomy in a work determines the strength of its aesthetic effect, and propose this could be experimentally tested. I conclude that scientific studies of aesthetic experience should take the dichotomous nature of artworks into account. PMID:26106312

  2. Cognitive and anatomical underpinnings of the conceptual knowledge for common objects and familiar people: a repetitive transcranial magnetic stimulation study.

    PubMed

    Campanella, Fabio; Fabbro, Franco; Urgesi, Cosimo

    2013-01-01

    Several studies have addressed the issue of how knowledge of common objects is organized in the brain, whereas the cognitive and anatomical underpinnings of familiar people knowledge have been less explored. Here we applied repetitive transcranial magnetic stimulation (rTMS) over the left and right temporal poles before asking healthy individuals to perform a speeded word-to-picture matching task using familiar people and common objects as stimuli. We manipulated two widely used semantic variables, namely the semantic distance and the familiarity of stimuli, to assess whether the semantic organization of familiar people knowledge is similar to that of common objects. For both objects and faces we reliably found semantic distance and familiarity effects, with less accurate and slower responses for stimulus pairs that were more closely related and less familiar. However, the effects of semantic variables differed across categories, with semantic distance effects larger for objects and familiarity effects larger for faces, suggesting that objects and faces might share a partially comparable organization of their semantic representations. The application of rTMS to the left temporal pole modulated, for both categories, semantic distance, but not familiarity effects, revealing that accessing object and face concepts might rely on overlapping processes within left anterior temporal regions. Crucially, rTMS of the left temporal pole affected only the recognition of pairs of stimuli that could be discriminated at specific levels of categorization (e.g., two kitchen tools or two famous persons), with no effect for discriminations at either superordinate or individual levels. Conversely, rTMS of the right temporal pole induced an overall slowing of reaction times that positively correlated with the visual similarity of the stimuli, suggesting a more perceptual rather than semantic role of the right anterior temporal regions. Results are discussed in the light of current

  3. Cognitive and Anatomical Underpinnings of the Conceptual Knowledge for Common Objects and Familiar People: A Repetitive Transcranial Magnetic Stimulation Study

    PubMed Central

    Campanella, Fabio; Fabbro, Franco; Urgesi, Cosimo

    2013-01-01

    Several studies have addressed the issue of how knowledge of common objects is organized in the brain, whereas the cognitive and anatomical underpinnings of familiar people knowledge have been less explored. Here we applied repetitive transcranial magnetic stimulation (rTMS) over the left and right temporal poles before asking healthy individuals to perform a speeded word-to-picture matching task using familiar people and common objects as stimuli. We manipulated two widely used semantic variables, namely the semantic distance and the familiarity of stimuli, to assess whether the semantic organization of familiar people knowledge is similar to that of common objects. For both objects and faces we reliably found semantic distance and familiarity effects, with less accurate and slower responses for stimulus pairs that were more closely related and less familiar. However, the effects of semantic variables differed across categories, with semantic distance effects larger for objects and familiarity effects larger for faces, suggesting that objects and faces might share a partially comparable organization of their semantic representations. The application of rTMS to the left temporal pole modulated, for both categories, semantic distance, but not familiarity effects, revealing that accessing object and face concepts might rely on overlapping processes within left anterior temporal regions. Crucially, rTMS of the left temporal pole affected only the recognition of pairs of stimuli that could be discriminated at specific levels of categorization (e.g., two kitchen tools or two famous persons), with no effect for discriminations at either superordinate or individual levels. Conversely, rTMS of the right temporal pole induced an overall slowing of reaction times that positively correlated with the visual similarity of the stimuli, suggesting a more perceptual rather than semantic role of the right anterior temporal regions. Results are discussed in the light of current

  4. Integrating ergonomics into engineering design: the role of objects.

    PubMed

    Hall-Andersen, Lene Bjerg; Broberg, Ole

    2014-05-01

    The objective of this study was to explore the role of objects in integrating ergonomic knowledge in engineering design processes. An engineering design case was analyzed using the theoretical concepts of boundary objects and intermediary objects: Boundary objects facilitate collaboration between different knowledge domains, while the aim of an intermediary object is to circulate knowledge and thus produce a distant effect. Adjustable layout drawings served as boundary objects and had a positive impact on the dialog between an ergonomist and designers. An ergonomic guideline document was identified as an intermediary object. However, when the ergonomic guidelines were circulated in the design process, only some of the guidelines were transferred to the design of the sterile processing plant. Based on these findings, recommendations for working with objects in design processes are included. PMID:24148875

  5. The Effects of Simultaneous Prompting on Teaching Expressive Identification of Objects: An Instructive Feedback Study.

    ERIC Educational Resources Information Center

    Tekin-Iftar, Elif; Acar, Gazi; Kurt, Onur

    2003-01-01

    This study with three adolescents with mental retardation examined whether the use of a simultaneous prompting procedure would result in improved performance when expressively identifying first aid materials. All three students learned the identifications and maintained them after training. Students also acquired and maintained some of the…

  6. Study of the Relationship between Leader-Member Exchange (LMX) and Individual Objective Performance within a University Learning Community

    ERIC Educational Resources Information Center

    Aikens, Shontarius D.

    2012-01-01

    The study examined the relationship between leader-member exchange (LMX) and individual objective performance. While the LMX literature suggests a positive correlation between LMX and performance, a closer look at the research examined showed that the performance measurements were based on subjective measurements rather than objective…

  7. A Study of the Scope, Sequence, and Objectives of Elementary School Science as Revealed by State Science Guides.

    ERIC Educational Resources Information Center

    Trout, Verdine E.

    Thirty-one state guides, published or revised between 1955 and 1964, were studied to examine (1) the major areas of science included, (2) the sequence of presentation by grades, (3) the recommended science concepts to be taught at each grade level, (4) the stated objectives of elementary school science as revealed by the guides, and (5) laboratory…

  8. Transformative learning in a professional development course aimed at addressing disruptive physician behavior: a composite case study.

    PubMed

    Samenow, Charles P; Worley, Linda L M; Neufeld, Ron; Fishel, Tobi; Swiggart, William H

    2013-01-01

    Disruptive physician behavior presents a challenge to the academic medical center. Such behaviors threaten the learning environment through increasing staff conflict, role modeling poor behaviors to trainees, and, ultimately, posing a risk to patient safety. Given that these physicians are often respected and valued for their clinical skills, many institutions struggle with how to best manage their behaviors. The authors present a composite case study of an academic physician referred to a professional development program for his disruptive behavior. They outline how transformative learning was applied to the development of concrete learning objectives, activities, and assessments for a curriculum aimed at promoting behavior change. Important themes include a safe group process in which the physician's assumptions are critically examined so that through experiential exercises and reflection, new roles, skills, and behaviors are learned, explored, and practiced. Timely feedback to the physician from the institution, colleagues, and administrators is critical to the physician's understanding of the impact of his or her behavior. Ultimately, the physician returns to practice demonstrating more professional behavior. Implications for medical education, prevention, and other professional development programs are discussed. PMID:23165281

  9. Toward Objective, Morphology-Based Taxonomy: A Case Study on the Malagasy Nesomyrmex sikorai Species Group (Hymenoptera: Formicidae).

    PubMed

    Csősz, Sándor; Fisher, Brian L

    2016-01-01

    Madagascar is one of the world's greatest biodiversity hotspots, meriting special attention from biodiversity scientists. It is an excellent testing ground for novel techniques in taxonomy that aim to increase classification objectivity and yield greater taxonomic resolving power. Here we reveal the diversity of a unique and largely unexplored fragment of the Malagasy ant fauna using an advanced combination of exploratory analyses on quantitative morphological data allowing for increased objectivity in taxonomic workflow. The diversity of the Nesomyrmex sikorai species-group was assessed via hypothesis-free nest-centroid-clustering combined with recursive partitioning to estimate the number of morphological clusters and determine the most probable boundaries between them. This combination of methods provides a highly automated and objective species delineation protocol based on continuous morphometric data. Delimitations of clusters recognized by these exploratory analyses were tested via confirmatory Linear Discriminant Analysis (LDA) and Multivariate Ratio Analysis (MRA). The final species hypotheses are corroborated by many qualitative characters, and the recognized species exhibit different spatial distributions and occupy different ecological regions. We describe and redescribe eight morphologically distinct species including six new species: Nesomyrmex excelsior sp. n., N. modestus sp. n., N. reticulatus sp. n., N. retusispinosus (Forel, 1892), N. rugosus sp. n., N. sikorai (Emery, 1896), N. striatus sp. n., and N. tamatavensis sp. n. An identification key for their worker castes using morphometric data is provided. PMID:27097219

  10. Toward Objective, Morphology-Based Taxonomy: A Case Study on the Malagasy Nesomyrmex sikorai Species Group (Hymenoptera: Formicidae)

    PubMed Central

    Csősz, Sándor; Fisher, Brian L.

    2016-01-01

    Madagascar is one of the world’s greatest biodiversity hotspots, meriting special attention from biodiversity scientists. It is an excellent testing ground for novel techniques in taxonomy that aim to increase classification objectivity and yield greater taxonomic resolving power. Here we reveal the diversity of a unique and largely unexplored fragment of the Malagasy ant fauna using an advanced combination of exploratory analyses on quantitative morphological data allowing for increased objectivity in taxonomic workflow. The diversity of the Nesomyrmex sikorai species-group was assessed via hypothesis-free nest-centroid-clustering combined with recursive partitioning to estimate the number of morphological clusters and determine the most probable boundaries between them. This combination of methods provides a highly automated and objective species delineation protocol based on continuous morphometric data. Delimitations of clusters recognized by these exploratory analyses were tested via confirmatory Linear Discriminant Analysis (LDA) and Multivariate Ratio Analysis (MRA). The final species hypotheses are corroborated by many qualitative characters, and the recognized species exhibit different spatial distributions and occupy different ecological regions. We describe and redescribe eight morphologically distinct species including six new species: Nesomyrmex excelsior sp. n., N. modestus sp. n., N. reticulatus sp. n., N. retusispinosus (Forel, 1892), N. rugosus sp. n., N. sikorai (Emery, 1896), N. striatus sp. n., and N. tamatavensis sp. n. An identification key for their worker castes using morphometric data is provided. PMID:27097219

  11. The Cooperative Health Research in South Tyrol (CHRIS) study: rationale, objectives, and preliminary results.

    PubMed

    Pattaro, Cristian; Gögele, Martin; Mascalzoni, Deborah; Melotti, Roberto; Schwienbacher, Christine; De Grandi, Alessandro; Foco, Luisa; D'Elia, Yuri; Linder, Barbara; Fuchsberger, Christian; Minelli, Cosetta; Egger, Clemens; Kofink, Lisa S; Zanigni, Stefano; Schäfer, Torsten; Facheris, Maurizio F; Smárason, Sigurður V; Rossini, Alessandra; Hicks, Andrew A; Weiss, Helmuth; Pramstaller, Peter P

    2015-01-01

    The Cooperative Health Research In South Tyrol (CHRIS) study is a population-based study with a longitudinal lookout to investigate the genetic and molecular basis of age-related common chronic conditions and their interaction with life style and environment in the general population. All adults of the middle and upper Vinschgau/Val Venosta are invited, while 10,000 participants are anticipated by mid-2017. Family participation is encouraged for complete pedigree reconstruction and disease inheritance mapping. After a pilot study on the compliance with a paperless assessment mode, computer-assisted interviews have been implemented to screen for conditions of the cardiovascular, endocrine, metabolic, genitourinary, nervous, behavioral, and cognitive system. Fat intake, cardiac health, and tremor are assessed instrumentally. Nutrient intake, physical activity, and life-course smoking are measured semi-quantitatively. Participants are phenotyped for 73 blood and urine parameters and 60 aliquots per participant are biobanked (cryo-preserved urine, DNA, and whole and fractionated blood). Through liquid-chromatography mass-spectrometry analysis, metabolite profiling of the mitochondrial function is assessed. Samples are genotyped on 1 million variants with the Illumina HumanOmniExpressExome array and the first data release including 4570 fully phenotyped and genotyped samples is now available for analysis. Participants' follow-up is foreseen 6 years after the first visit. The target population is characterized by long-term social stability and homogeneous environment which should both favor the identification of enriched genetic variants. The CHRIS cohort is a valuable resource to assess the contribution of genomics, metabolomics, and environmental factors to human health and disease. It is awaited that this will result in the identification of novel molecular targets for disease prevention and treatment. PMID:26541195

  12. Foreign Objects in the Rectum

    MedlinePlus

    ... Disease (Video) Appendicitis Additional Content Medical News Foreign Objects in the Rectum By Parswa Ansari, MD NOTE: ... Fissure Anal Itching Anorectal Abscess Anorectal Fistula Foreign Objects in the Rectum Hemorrhoids Levator Syndrome Pilonidal Disease ...

  13. Creating the First SCORM Object

    ERIC Educational Resources Information Center

    Gonzalez-Barbone, Victor; Anido-Rifon, Luis

    2008-01-01

    The creation of the first SCORM (Shareable Content Object Reference Model) object offers some challenges and difficulties which go beyond the facilities offered by content generation applications. In particular, the creation of really reusable, searchable learning objects requires a detailed consideration of metadata, where some institutional…

  14. The Use of Educational Objects

    ERIC Educational Resources Information Center

    Stearns, Clio

    2016-01-01

    This conceptual paper looks at the Winnicottian notion of object use as it relates to education. Object use is understood as the process of attaching to but then attempting to destroy the educator in an effort to create new knowledge and relationships. The paper argues for educational object use as a way of understanding and normalising resistance…

  15. A Review of Chemical Bonding Studies: Needs, Aims, Methods of Exploring Students' Conceptions, General Knowledge Claims and Students' Alternative Conceptions

    ERIC Educational Resources Information Center

    Unal, Suat; Calik, Muammer; Ayas, Alipasa; Coll, Richard K.

    2006-01-01

    The present paper presents a detailed thematic review of chemical bonding studies. To achieve this, a matrix is developed to summarize and present the findings by focusing on insights derived from the related studies. The matrix incorporates the following themes: needs, aims, methods of exploring students' conceptions, general knowledge claims,…

  16. The face of Smith-Magenis syndrome: a subjective and objective study.

    PubMed

    Allanson, J E; Greenberg, F; Smith, A C

    1999-05-01

    We report a study of 55 subjects with Smith-Magenis syndrome, aged 9 months to 35 years. Each person has been evaluated with an assessment of "gestalt" and detailed facial measurement, using previously published methodology, with compilation of Z score pattern profiles. The facial phenotype of SMS is quite distinctive, even in the young child. The overall face shape is broad and square. The brows are heavy, with excessive lateral extension of the eyebrows. The eyes slant upwards and appear close set and deep set. The nose has a depressed root and, in the young child, a scooped bridge. With time, the bridge becomes more ski jump shaped. The height of the nose is markedly reduced while the nasal base is broad and the tip of the nose is full. The shape of the mouth and upper lip are most distinctive. The mouth is wide with full upper and lower lips. The central portion of the upper lip is fleshy and everted with bulky philtral pillars, producing a tented appearance that, in profile, is striking. With age, mandibular growth is greater than average and exceeds that of the maxilla. This leads to increased jaw width and protrusion and marked midface hypoplasia. Craniofacial pattern analysis supports these subjective impressions. After mid-childhood, mandibular dimensions consistently exceed their maxillary counterparts. Craniofacial widths are greater than corresponding depths and heights. Nasal height is reduced while nasal width is increased. There is mild brachycephaly. The most marked age related changes are increased width of the nose and lower face (mandibular width) with reduction in nasal height and midfacial depth. PMID:10353786

  17. Earth's gravity gradient and eddy currents effects on the rotational dynamics of space debris objects: Envisat case study

    NASA Astrophysics Data System (ADS)

    Gómez, Natalia Ortiz; Walker, Scott J. I.

    2015-08-01

    The space debris population has grown rapidly over the last few decades with the consequent growth of impact risk between current objects in orbit. Active Debris Removal (ADR) has been recommended to be put into practice by several National Agencies in order to remove objects that pose the biggest risk for the space community. The most immediate target that is being considered for ADR by the European Space Agency is the Earth-observing satellite Envisat. In order to safely remove such a massive object from its orbit, a capturing process followed by a controlled reentry is necessary. However, current ADR methods that require physical contact with the target have limitations on the maximum angular momentum that can be absorbed and a de-tumbling phase prior to the capturing process may be required. Therefore, it is of utmost importance for the ADR mission design to be able to predict accurately how the target will be rotating at the time of capture. This article analyses two perturbations that affect an object in Low Earth Orbit (LEO), the Earth's gravity gradient and the eddy currents induced by the Earth's magnetic field. The gravity gradient is analysed using the equation of conservation of total energy and a graphical method is presented to understand the expected behaviour of any object under the effect of this perturbation. The eddy currents are also analysed by studying the total energy of the system. The induced torque and the characteristic time of decay are presented as a function of the object's magnetic tensor. In addition, simulations were carried out for the Envisat spacecraft including the gravity gradient perturbation as well as the eddy currents effect using the International Geomagnetic Reference Field IGRF-11 to model the Earth's magnetic field. These simulations show that the combined effect of these two perturbations is a plausible explanation for the rotational speed decay observed between April 2013 and September 2013.

  18. A COMPARATIVE ASTROCHEMICAL STUDY OF THE HIGH-MASS PROTOSTELLAR OBJECTS NGC 7538 IRS 9 AND IRS 1

    SciTech Connect

    Barentine, John C.; Lacy, John H.

    2012-10-01

    We report the results of a spectroscopic study of the high-mass protostellar object NGC 7538 IRS 9 and compare our observations to published data on the nearby object NGC 7538 IRS 1. Both objects originated in the same molecular cloud and appear to be at different points in their evolutionary histories, offering an unusual opportunity to study the temporal evolution of envelope chemistry in objects sharing a presumably identical starting composition. Observations were made with the Texas Echelon Cross Echelle Spectrograph, a sensitive, high spectral resolution (R {lambda}/{Delta}{lambda} {approx_equal} 100,000) mid-infrared grating spectrometer. Forty-six individual lines in vibrational modes of the molecules C{sub 2}H{sub 2}, CH{sub 4}, HCN, NH{sub 3}, and CO were detected, including two isotopologues ({sup 13}CO, {sup 12}C{sup 18}O) and one combination mode ({nu}{sub 4} + {nu}{sub 5} C{sub 2}H{sub 2}). Fitting synthetic spectra to the data yielded the Doppler shift, excitation temperature, Doppler b parameter, column density, and covering factor for each molecule observed; we also computed column density upper limits for lines and species not detected, such as HNCO and OCS. We find differences among spectra of the two objects likely attributable to their differing radiation and thermal environments. Temperatures and column densities for the two objects are generally consistent, while the larger line widths toward IRS 9 result in less saturated lines than those toward IRS 1. Finally, we compute an upper limit on the size of the continuum-emitting region ({approx}2000 AU) and use this constraint and our spectroscopy results to construct a schematic model of IRS 9.

  19. The Object of Their Attention

    ERIC Educational Resources Information Center

    Tishman, Shari

    2008-01-01

    Tishman argues that directing students to closely examine physical objects is an excellent way to motivate and strengthen thinking. Even simple objects reflect the social and physical contexts in which they were created and can spur deeper observations and questions. Teaching thinking through objects appeals to many different kinds of learners and…

  20. A Study on Pedagogical Requirements for Multi-platform Learning Objects

    NASA Astrophysics Data System (ADS)

    Behar, Patricia Alejandra; Passerino, Liliana Maria; de Castro E Souza Frozi, Ana Paula Frozi; de Oliveira Dias, Cristiani; da Silva, Ketia Kellen Araújo

    This study presents the development of a proposal of pedagogical requirements for multi-platform learning objects (LO). It aims at providing a debate on the importance of such pedagogical requirements in the development and construction of LOs. It also demonstrates an analysis of these requirements performed with a built learning object operating in the Web, digital TV (DTV) and cell phone.

  1. Subjective and objective parameters in the evaluation of radiofrequency ablation of the inferior turbinate do not correlate: A pilot study.

    PubMed

    Tomazic, Peter Valentin; Gerstenberger, Claus; Rant, Bettina; Nemetz, Ulrike; Brezjak-Kahlert, Christiana; Wolf, Axel; Freudenschuss, Kurt; Wolf, Gerald

    2016-08-01

    Inferior turbinate hypertrophy is a common cause of nasal obstruction. We conducted a prospective study to correlate subjective and objective parameters in assessing the effectiveness of radiofrequency ablation (RFA). Our initial study population was made up of 10 patients who presented with nasal obstruction; 1 patient was lost to follow-up, leaving us with 7 women and 2 men, aged 26 to 65 years (mean: 37.9 ± 12.8), and 16 turbinates (7 bilateral, 1 right, and 1 left). Visual analogue scale (VAS) scores, Nasal Obstruction and Symptom Evaluation (NOSE) questionnaire scores, rhinomanometry results, and CT- and MRI-based volumetry were obtained before RFA and 6 months afterward. For the subjective parameters, the mean pre- and postoperative VAS scores for the 16 turbinates were 6.6 ± 1.6 and 2.8 ± 2.0 (p < 0.001), respectively, and the mean pre- and postoperative NOSE scores in the 9 patients were 15.3 ± 3.1 and 5.8 ± 5.4 (p = 0.003). For the objective parameters, the mean pre- and postoperative rhinomanometry values at 150 Pa were 241.0 ± 141.3 and 265.4 ± 157.3 ml/sec (p = 0.403), and the mean pre- and postoperative volumetry values were 5.3 ± 2.5 and 5.0 ± 2.1 cm(3) (p = 0.551). Note that only the differences in the subjective parameters reached statistical significance. RFA of the inferior turbinates as a treatment for nasal obstruction is safe and easy. However, our study found a discrepancy between the subjective and objective outcomes parameters, as the former showed highly significant improvement and the latter showed only a slight improvement that did not reach statistical significance. PMID:27551845

  2. Objects, events and "to be" verbs in Spanish--an ERP study of the syntax-semantics interface.

    PubMed

    Leone-Fernandez, Barbara; Molinaro, Nicola; Carreiras, Manuel; Barber, Horacio A

    2012-02-01

    In Spanish, objects and events at subject position constrain the selection of different forms of the auxiliary verb "to be": locative predicates about objects require "estar en", while those relating to events require "ser en", both translatable as "to be in". Subjective ratings showed that while the "object+ser+en" is considered as incorrect, the "event+estar+en" combination is also perceived as unacceptable but to a lesser degree. In an ERP study, we evaluated the impact of a purely semantic distinction (object versus events) on the subsequent processing of these auxiliary verbs followed by locatives in Spanish. For the "ser en" predicate, the P600 component was larger when the subject was an object than when it was an event. This P600 effect is consistent with an online repair of the defining predicate when it does not fit with the adequate semantic properties of the subject. On the other hand, for the "estar en" predicate, event subjects when compared to object subjects showed more positive ongoing amplitudes between 280 and 380 ms after the presentation of the "en" preposition, followed by a longer positive wave starting around 400 ms and lasting until 700 ms after the presentation of the following determiner, with central and frontal scalp distributions respectively. Thus, the different subject-predicate combinations, depending on the semantic features of the subjects, triggered syntactic reparatory processes at a structural level. These findings are consistent with an incremental interpretation of sentence meaning based on the interaction between syntactic and semantic information. PMID:21300400

  3. Studying the effect of the Semipalatinsk Test Site on radionuclide and elemental composition of water objects in the Irtysh River.

    PubMed

    Solodukhin, V; Аidarkhanov, A; Lukashenko, S; Gluchshenko, V; Poznyak, V; Lyahova, O

    2015-06-01

    The results of the field and laboratory studies of radiation and environmental state at the specific area of Irtysh River adjacent to the Semipalatinsk Test Site are provided. It was found that the radiation situation in this area is normal: equivalent dose of γ-radiation = (0.11-0.13) µSv h(-1). Determination of radionuclide composition of soil, bottom sediment and water samples was performed by the methods of instrumental γ-spectrometry, radiochemical analysis and the liquid scintillation β-spectrometry. It was found that concentrations of the studied natural and artificial radionuclides in these objects are very low; no contamination with radionuclides was detected in this segment of Irtysh River. The article provides the results of elemental composition determination for samples of soil and bottom sediment (by X-ray fluorescence method) and water samples (by inductively coupled plasma mass spectrometry method). It is shown that the content of some elements (Li, Be, B, V, Cu, Sr, Mo) in the water of Irtysh River increases downstream. The additional studies are required to explain this peculiarity. PMID:25971345

  4. The self-consistent field study of the adsorption of flexible polyelectrolytes onto two charged nano-objects.

    PubMed

    Tong, Chaohui; Zhu, Yuejin; Zhang, Hongdong; Qiu, Feng; Tang, Ping; Yang, Yuliang

    2011-10-01

    The continuum self-consistent field theory (SCFT) is applied to the study of the adsorption of flexible polyelectrolyte (PE) onto the surfaces of two two-dimensional charged square objects with a constant electric field strength immersed in a weakly charged polyelectrolyte solution. The dependences of the different chain conformations, that is, bridging, loop, tail, and train, and in particular, the bridging chain conformation, on various system parameters (the charge fraction of the PE chains, the surface charge density, the object size, the salt concentration, etc.) are investigated. The efficient multigrid method is adopted to numerically solve the modified diffusion equation and the Poisson equation. It is found that the thickness L(B) of the boundary layer of the adsorbed PE chains is independent of the chain length and scales with the surface charge density σ and the fraction of charges on PE chains α(P) as L(B) ~ σ(-0.36) and L(B) ~ α(P)(-0.36), respectively. Simulation results reveal that the total amount of bridging chain conformation in the system scales linearly with respect to the size of the charge objects and scales linearly with the chain length in the long polymer chain regime. Simulation results reveal that the total amount of the bridging chain conformation in the system scales with the charge fraction of PE chains as a power law and the scaling exponent is dependent on all of the other system parameters. Simulation results show that the total amount of charges on the adsorbed chains in the system can overcompensate the surface charges for relatively long chains with high charge fractions. PMID:21888311

  5. Beyond the “urge to move”: objective measures for the study of agency in the post-Libet era

    PubMed Central

    Rowe, James B.

    2014-01-01

    The investigation of human volition is a longstanding endeavor from both philosophers and researchers. Yet because of the major challenges associated with capturing voluntary movements in an ecologically relevant state in the research environment, it is only in recent years that human agency has grown as a field of cognitive neuroscience. In particular, the seminal work of Libet et al. (1983) paved the way for a neuroscientific approach to agency. Over the past decade, new objective paradigms have been developed to study agency, drawing upon emerging concepts from cognitive and computational neuroscience. These include the chronometric approach of Libet’s study which is embedded in the “intentional binding” paradigm, optimal motor control theory and most recent insights from active inference theory. Here we review these principal methods and their application to the study of agency in health and the insights gained from their application to neurological and psychiatric disorders. We show that the neuropsychological paradigms that are based upon these new approaches have key advantages over traditional experimental designs. We propose that these advantages, coupled with advances in neuroimaging, create a powerful set of tools for understanding human agency and its neurobiological basis. PMID:24999325

  6. Measuring Motivation Multidimensionally: Development of the Assessment of Individual Motives-Questionnaire (AIM-Q)

    ERIC Educational Resources Information Center

    Bernard, Larry C.; Mills, Michael; Swenson, Leland; Walsh, R. Patricia

    2008-01-01

    We report the development of the Assessment of Individual Motives-Questionnaire (AIM-Q), a new instrument based on an evolutionary psychology theory of human motivation. It provides multitrait-multimethod (MTMM) assessment of individual differences on 15 motive scales. A total heterogeneous sample of N = 1,251 participated in eight studies that…

  7. Study of a new central compact object: The neutron star in the supernova remnant G15.9+0.2

    NASA Astrophysics Data System (ADS)

    Klochkov, D.; Suleimanov, V.; Sasaki, M.; Santangelo, A.

    2016-08-01

    We present our study of the central point source CXOU J181852.0-150213 in the young Galactic supernova remnant (SNR) G15.9+0.2 based on the recent ~90 ks Chandra observations. The point source was discovered in 2005 in shorter Chandra observations and was hypothesized to be a neutron star associated with the SNR. Our X-ray spectral analysis strongly supports the hypothesis of a thermally emitting neutron star associated with G15.9+0.2. We conclude that the object belongs to the class of young cooling low-magnetized neutron stars referred to as central compact objects (CCOs). We modeled the spectrum of the neutron star with a blackbody spectral function and with our hydrogen and carbon neutron star atmosphere models, assuming that the radiation is uniformly emitted by the entire stellar surface. Under this assumption, only the carbon atmosphere models yield a distance that is compatible with a source located in the Galaxy. In this respect, CXOU J181852.0-150213 is similar to two other well-studied CCOs, the neutron stars in Cas A and in HESS J1731-347, for which carbon atmosphere models were used to reconcile their emission with the known or estimated distances.

  8. The linguistic context effects on the processing of body-object interaction words: An ERP study on second language learners.

    PubMed

    Xue, Jin; Marmolejo-Ramos, Fernando; Pei, Xuna

    2015-07-10

    Embodied theories of cognition argue that the processing of both concrete and abstract concepts requires the activation of sensorimotor systems. The present study examined the time course for embedding a sensorimotor context in order to elicit sensitivity to the sensorimotor consequences of understanding body-object interaction (BOI) words. In the study, Event-Related Potentials (ERPs) were recorded while subjects performed a sentence acceptability task. Target BOI words were preceded by rich or poor sensorimotor sentential contexts. The behavioural results replicated previous findings in that high BOI words received a response faster than low BOI words. In addition to this, however, there was a context effect in the sensorimotor region as well as a BOI effect in the parietal region (involved in object representation). The results indicate that the sentential sensorimotor context contributes to the subsequent BOI processing and that action-and perception-related language leads to the activation of the same brain areas, which is consistent with the embodiment theory. PMID:25858488

  9. Object oriented studies into artificial space debris

    NASA Technical Reports Server (NTRS)

    Adamson, J. M.; Marshall, G.

    1988-01-01

    A prototype simulation is being developed under contract to the Royal Aerospace Establishment (RAE), Farnborough, England, to assist in the discrimination of artificial space objects/debris. The methodology undertaken has been to link Object Oriented programming, intelligent knowledge based system (IKBS) techniques and advanced computer technology with numeric analysis to provide a graphical, symbolic simulation. The objective is to provide an additional layer of understanding on top of conventional classification methods. Use is being made of object and rule based knowledge representation, multiple reasoning, truth maintenance and uncertainty. Software tools being used include Knowledge Engineering Environment (KEE) and SymTactics for knowledge representation. Hooks are being developed within the SymTactics framework to incorporate mathematical models describing orbital motion and fragmentation. Penetration and structural analysis can also be incorporated. SymTactics is an Object Oriented discrete event simulation tool built as a domain specific extension to the KEE environment. The tool provides facilities for building, debugging and monitoring dynamic (military) simulations.

  10. Object links in the repository

    NASA Technical Reports Server (NTRS)

    Beck, Jon; Eichmann, David

    1991-01-01

    Some of the architectural ramifications of extending the Eichmann/Atkins lattice-based classification scheme to encompass the assets of the full life-cycle of software development are explored. In particular, we wish to consider a model which provides explicit links between objects in addition to the edges connecting classification vertices in the standard lattice. The model we consider uses object-oriented terminology. Thus, the lattice is viewed as a data structure which contains class objects which exhibit inheritance. A description of the types of objects in the repository is presented, followed by a discussion of how they interrelate. We discuss features of the object-oriented model which support these objects and their links, and consider behavior which an implementation of the model should exhibit. Finally, we indicate some thoughts on implementing a prototype of this repository architecture.

  11. Using the RE-AIM framework to evaluate physical activity public health programs in Mexico

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Physical activity (PA) public health programming has been widely used in Mexico; however, few studies have documented individual and organizational factors that might be used to evaluate their public health impact. The RE-AIM framework is an evaluation tool that examines individual and organizationa...

  12. [Comparative sonographic-anatomic studies aimed at demonstrating intrarenal fine structure].

    PubMed

    Zilch, H G; Posel, P

    1985-07-01

    The detailed structure of the kidneys was studied in 40 excised organs by means of high resolution sonography. It becomes possible to differentiate the details within the renal parenchyma and the sinus. Intrarenal vascular details can also be defined. The clinical relevance of these results is discussed. PMID:2992015

  13. Interactive and Independent Associations between the Socioeconomic and Objective Built Environment on the Neighbourhood Level and Individual Health: A Systematic Review of Multilevel Studies

    PubMed Central

    Schüle, Steffen Andreas; Bolte, Gabriele

    2015-01-01

    Background The research question how contextual factors of neighbourhood environments influence individual health has gained increasing attention in public health research. Both socioeconomic neighbourhood characteristics and factors of the built environment play an important role for health and health-related behaviours. However, their reciprocal relationships have not been systematically reviewed so far. This systematic review aims to identify studies applying a multilevel modelling approach which consider both neighbourhood socioeconomic position (SEP) and factors of the objective built environment simultaneously in order to disentangle their independent and interactive effects on individual health. Methods The three databases PubMed, PsycINFO, and Web of Science were systematically searched with terms for title and abstract screening. Grey literature was not included. Observational studies from USA, Canada, Australia, New Zealand, and Western European countries were considered which analysed simultaneously factors of neighbourhood SEP and the objective built environment with a multilevel modelling approach. Adjustment for individual SEP was a further inclusion criterion. Results Thirty-three studies were included in qualitative synthesis. Twenty-two studies showed an independent association between characteristics of neighbourhood SEP or the built environment and individual health outcomes or health-related behaviours. Twenty-one studies found cross-level or within-level interactions either between neighbourhood SEP and the built environment, or between neighbourhood SEP or the built environment and individual characteristics, such as sex, individual SEP or ethnicity. Due to the large variation of study design and heterogeneous reporting of results the identification of consistent findings was problematic and made quantitative analysis not possible. Conclusions There is a need for studies considering multiple neighbourhood dimensions and applying multilevel

  14. Creating objects and object categories for studying perception and perceptual learning.

    PubMed

    Hauffen, Karin; Bart, Eugene; Brady, Mark; Kersten, Daniel; Hegdé, Jay

    2012-01-01

    In order to quantitatively study object perception, be it perception by biological systems or by machines, one needs to create objects and object categories with precisely definable, preferably naturalistic, properties. Furthermore, for studies on perceptual learning, it is useful to create novel objects and object categories (or object classes) with such properties. Many innovative and useful methods currently exist for creating novel objects and object categories (also see refs. 7,8). However, generally speaking, the existing methods have three broad types of shortcomings. First, shape variations are generally imposed by the experimenter, and may therefore be different from the variability in natural categories, and optimized for a particular recognition algorithm. It would be desirable to have the variations arise independently of the externally imposed constraints. Second, the existing methods have difficulty capturing the shape complexity of natural objects. If the goal is to study natural object perception, it is desirable for objects and object categories to be naturalistic, so as to avoid possible confounds and special cases. Third, it is generally hard to quantitatively measure the available information in the stimuli created by conventional methods. It would be desirable to create objects and object categories where the available information can be precisely measured and, where necessary, systematically manipulated (or 'tuned'). This allows one to formulate the underlying object recognition tasks in quantitative terms. Here we describe a set of algorithms, or methods, that meet all three of the above criteria. Virtual morphogenesis (VM) creates novel, naturalistic virtual 3-D objects called 'digital embryos' by simulating the biological process of embryogenesis. Virtual phylogenesis (VP) creates novel, naturalistic object categories by simulating the evolutionary process of natural selection. Objects and object categories created by these simulations can

  15. The Power of Objectives: Moving beyond Learning Objectives

    ERIC Educational Resources Information Center

    Phillips, Jack J.; Phillips, Patti P.

    2010-01-01

    Although the need for project objectives is obvious, their value and role are much broader than most think. In this article, we explore the need for higher levels of objectives, along with tips and techniques to develop them properly. More important, we examine the benefits of objectives from many perspectives. In today's competitive environment,…

  16. Making CORBA objects persistent: The object database adapter approach

    SciTech Connect

    Reverbel, F.C.R.

    1997-05-01

    In spite of its remarkable successes in promoting standards for distributed object systems, the Object Management Group (OMG) has not yet settled the issue of object persistence in the Object Request Broker (ORB) environment. The Common Object Request Broker Architecture (CORBA) specification briefly mentions an Object-Oriented Database Adapter that makes objects stored in an object-oriented database accessible through the ORB. This idea is pursued in the Appendix B of the ODMG standard, which identifies a number of issues involved in using an Object Database Management System (ODBMS) in a CORBA environment, and proposes an Object Database Adapter (ODA) to realize the integration of the ORB with the ODBMS. This paper discusses the design and implementation of an ODA that integrates an ORB and an ODBMS with C++ bindings. For the author`s purposes, an ODBMS is a system with programming interfaces. It may be a pure object-oriented DBMS (an OODBMS), or a combination of a relational DBMS and an object-relational mapper.

  17. The uncrowded window of object recognition

    PubMed Central

    Pelli, Denis G; Tillman, Katharine A

    2009-01-01

    It is now emerging that vision is usually limited by object spacing rather than size. The visual system recognizes an object by detecting and then combining its features. ‘Crowding’ occurs when objects are too close together and features from several objects are combined into a jumbled percept. Here, we review the explosion of studies on crowding—in grating discrimination, letter and face recognition, visual search, selective attention, and reading—and find a universal principle, the Bouma law. The critical spacing required to prevent crowding is equal for all objects, although the effect is weaker between dissimilar objects. Furthermore, critical spacing at the cortex is independent of object position, and critical spacing at the visual field is proportional to object distance from fixation. The region where object spacing exceeds critical spacing is the ‘uncrowded window’. Observers cannot recognize objects outside of this window and its size limits the speed of reading and search. PMID:18828191

  18. The Relationship of Reading Information and Communication Technology (ICT) to Opportunity Structure: An Object of Study?

    ERIC Educational Resources Information Center

    Freebody, Peter; Hornibrook, Margery

    2005-01-01

    Eric Hobsbawm, perhaps the preeminent historian writing in English about the 19th and 20th centuries, previewed his encyclopedic account of the last 100 years with descriptions of the organizationally, collectively, and individually brutalizing effects of the intense round of wars, revolutions, and economic fluctuations that were the hallmark of…

  19. Making Geography Visible as an Object of Study in the Secondary School Curriculum

    ERIC Educational Resources Information Center

    Firth, Roger

    2011-01-01

    This article considers disciplinary-based knowledge and its recontextualisation and acquisition in the secondary school curriculum. It starts from the premise that teaching disciplinary knowledge is important. The focus is the subject of geography and the increasingly influential realist school of thought in the sociology of education and the…

  20. Multi-instrument variability study of the classical TeV objects Mrk 421 and Mrk 501

    NASA Astrophysics Data System (ADS)

    Nowak, N.; Doert, M.; Paneque, D.; de Almeida, U. Barres; Pichel, A.; Tescaro, D.; Benbow, W.

    2012-12-01

    The BL Lac objects Mrk 421 and Mrk 501 are objects of a large multi-year multiinstrument campaign including VLBA, F-GAMMA, GASP-WEBT, Swift, RXTE, Fermi-LAT, MAGIC and VERITAS, among other instruments and collaborations. This extensive radio to TeV gamma-ray dataset provides an unprecedented temporal and energy coverage, which allows for detailed studies of the evolution of their broad-band spectral energy distribution that cannot be achieved on any other BL Lac object. We report on the temporal variability and spectral correlations from the 4.5 months-long campaigns of 2009. We show that Mrk 421 and Mrk 501 have differences in their broad band variability, suggesting different mechanisms for the production of the high-energy emission. In addition, we also report on two events of high activity in very high energies (VHE) of Mrk 501 during May 2009, one of which was not accompanied by enhanced optical/X-ray activity but showed a clear correlation with an increase in the polarized optical flux and a rotation of the polarization vector. This is the first time that such type of flaring activity is observed in a high-synchrotron-peaked BL Lac object.

  1. The Social Ailments of Russian Society as an Object of Sociological Study

    ERIC Educational Resources Information Center

    Ryvkina, R. V.

    2010-01-01

    Social systems, like biological systems, sometimes manifest dysfunctions that could be considered forms of "social disease." The author interprets the term "social diseases" as "persistent dysfunctions of social relations" that disrupt the normal functioning of particular elements of society or the entire social system as a whole. The author cites…

  2. Polarization studies of atmospheric objects in the low troposphere by lidar

    SciTech Connect

    Kolev, I.; Kaprielov, B.; Tatarov, B.; Trifonov, T.

    1996-12-31

    In the present work some results of polarization measurements in the planetary boundary layer are reported. The observations described were performed by a ground-based lidar over the region of the Sofia city (where various industrial enterprises exist along with a heavy transport and aerial communications). The data obtained when sounding in different meteorological situations (clear atmosphere, rain, fog, snowfall) are considered. Certain differences are established in the depolarization properties of clear atmosphere in dependence of the meteorological condition. The developments of fog and snowfall are traced; the effects of the underlying surface are sought when sounding in fog; various types of situations during a snowfall are pointed out as well. An attempt is made to follow the development of the processes which proceed during an interaction between air masses with different properties (e.g., a front advection); as a result the formation of the cloud system over the region is traced. Definite differences between the microphysical properties of the aerosol near the clouds base and top are established as well.

  3. Special Programs Aimed at Reaching Children: S.P.A.R.C. Case Studies II.

    ERIC Educational Resources Information Center

    Silberman, Adolph, Ed.; And Others

    This case study booklet, written by the program's counseling staff, evolved from five actual cases in which a psychologist and counselors were involved. Both the techniques and the results are specified in the hope that counselors and psychologists in other districts will attempt similar methods in helping children with deviant behavior problems.…

  4. Laboratory studies of the diffuse reflectance spectra of frosts and minerals occurring on astronomical objects

    NASA Technical Reports Server (NTRS)

    Glaser, F. M.

    1978-01-01

    A vacuum monochromator was integrated into the system and optics chosen to increase data collection in the infrared spectral region. Using a InSb detector, good reflectance data was obtained to 5.5 micron from a variety of samples including magnesium oxide, barium sulfate, water frost and Bloedite. Magnesium oxide was found to be a poorer reflector than the barium sulfate throughout the visible and near infrared region. The barium sulfate material was shown to be a Lambert reflector in the visible region and over an angular range of 60 deg. Several samples of water frost were prepared and in reflectance measured from 0.3 micron to 5.5 microm. The fine grained frosts were better reflectors than the coarse grained frosts, usually by 20 percent or more, over the entire spectral range. The minerals Bloedite and sulfur were also investigated further.

  5. [The dental professional action and aim to the struggle for large earthquake].

    PubMed

    Li, Gang

    2008-06-01

    On May 12, 2008, a magnitude 8 earthquake struck the eastern Sichuan Province in China. The quake could be felt as far away as Bangkok, Thailand, Taiwan, Vietnam, Shanghai, and Beijing. Officials say that at least 69170 may have been killed and local reports indicate over 374159 injured till June 16, 2008. A study of the dental professional action to the struggle for the Sichuan large earthquake is reported. The dental professional action and aim to the struggle for large earthquake are discussed. It is believed that dental professional personals must make more specific contribution in quake-hit areas in the future via supplies of well organized services. PMID:18661058

  6. Sex Education for Teachers in Training. The Preliminary Report of a Pilot Study on Objective Tests

    ERIC Educational Resources Information Center

    Rout, Neil; Painter, Marjorie

    1972-01-01

    Students in 14 teacher colleges in Great Britian were given tests to assess their knowledge of the reproductive system, genetics, and venereal diseases. Test results indicate the necessity for intensive health education courses in Colleges of Education. (DS)

  7. Further laboratory study of the diffuse reflectance spectra of frosts occurring on astronomical objects

    NASA Technical Reports Server (NTRS)

    Glaser, F. M.

    1976-01-01

    Oligoclase and bloedite, two mined samples, have been investigated, and the diffuse reflectance spectra are presented. These data are for powdered material, 50 microns to 5 microns size mixture, cooled to 160 K. The reflectivity of the oligoclase sample was also measured at room temperature, about 290 K, and the results at these two temperatures do indicate some tentative differences. A frost of ordinary water was prepared and its spectral reflectance is presented. This result compares reasonably well with measurements made by other investigators.

  8. The Neural Correlates of Object-Centered Processing in Reading: A Lesion Study of Neglect Dyslexia

    ERIC Educational Resources Information Center

    Ptak, Radek; Di Pietro, Marie; Schnider, Armin

    2012-01-01

    Neglect dyslexia--a peripheral reading disorder generally associated with left spatial neglect--is characterized by omissions or substitutions of the initial letters of words. Several observations suggest that neglect dyslexia errors are independent of viewer-centered coordinates; the disorder is therefore thought to reflect impairment at the…

  9. X-ray studies of solar system objects: now and the next decade

    NASA Astrophysics Data System (ADS)

    Branduardi-Raymont, G.

    2016-06-01

    XMM-Newton and Chandra have revealed the multiplicity of X-ray emissions from planets, comets and minor bodies in our solar system. This presentation will review the main findings so far and will look forward to the unique contributions that XMM-Newton can continue to provide in solar system exploration. As a prime example, Jupiter's polar regions show bright soft X-ray aurorae with a line-rich spectrum arising from charge exchange interactions of atmospheric neutrals with local and/or solar wind high charge-state heavy ions. At energies above ˜3 keV the auroral X-ray spectrum is featureless, pointing to an origin from electron bremsstrahlung. Jupiter's atmosphere scatters solar X-rays, so that the planet's disk displays an X-ray spectrum that closely resembles that of solar flares. The arrival of Juno at Jupiter this July will enable in situ measurements simultaneous with XMM-Newton observations, offering unique opportunities to validate models developed to describe the planet's behaviour. Unlike Jupiter, Mars and Venus lack a strong magnetic field, yet they show X-ray emissions from their disks and exospheres, via solar X-ray scattering and charge exchange. Future XMM-Newton observations of solar system targets, under different solar activity conditions, will provide ever deeper insights into their close relationships with their parent star.

  10. Objects, Events and "to Be" Verbs in Spanish--An ERP Study of the Syntax-Semantics Interface

    ERIC Educational Resources Information Center

    Leone-Fernandez, Barbara; Molinaro, Nicola; Carreiras, Manuel; Barber, Horacio A.

    2012-01-01

    In Spanish, objects and events at subject position constrain the selection of different forms of the auxiliary verb "to be": locative predicates about objects require "estar en", while those relating to events require "ser en", both translatable as "to be in". Subjective ratings showed that while the "object + ser + en" is considered as incorrect,…

  11. Using the RE-AIM framework in formative evaluation and program planning for a nutrition intervention in the Lower Mississippi Delta

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The objective of this study is the identification of prominent themes to be considered when planning a nutrition intervention using the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework. Qualitative formative research was used on women's social and civic organization...

  12. The development of multi-objective optimization model for excess bagasse utilization: A case study for Thailand

    SciTech Connect

    Buddadee, Bancha Wirojanagud, Wanpen Watts, Daniel J. Pitakaso, Rapeepan

    2008-08-15

    In this paper, a multi-objective optimization model is proposed as a tool to assist in deciding for the proper utilization scheme of excess bagasse produced in sugarcane industry. Two major scenarios for excess bagasse utilization are considered in the optimization. The first scenario is the typical situation when excess bagasse is used for the onsite electricity production. In case of the second scenario, excess bagasse is processed for the offsite ethanol production. Then the ethanol is blended with an octane rating of 91 gasoline by a portion of 10% and 90% by volume respectively and the mixture is used as alternative fuel for gasoline vehicles in Thailand. The model proposed in this paper called 'Environmental System Optimization' comprises the life cycle impact assessment of global warming potential (GWP) and the associated cost followed by the multi-objective optimization which facilitates in finding out the optimal proportion of the excess bagasse processed in each scenario. Basic mathematical expressions for indicating the GWP and cost of the entire process of excess bagasse utilization are taken into account in the model formulation and optimization. The outcome of this study is the methodology developed for decision-making concerning the excess bagasse utilization available in Thailand in view of the GWP and economic effects. A demonstration example is presented to illustrate the advantage of the methodology which may be used by the policy maker. The methodology developed is successfully performed to satisfy both environmental and economic objectives over the whole life cycle of the system. It is shown in the demonstration example that the first scenario results in positive GWP while the second scenario results in negative GWP. The combination of these two scenario results in positive or negative GWP depending on the preference of the weighting given to each objective. The results on economics of all scenarios show the satisfied outcomes.

  13. The role of the dorsal dentate gyrus in object and object-context recognition.

    PubMed

    Dees, Richard L; Kesner, Raymond P

    2013-11-01

    The aim of this study was to determine the role of the dorsal dentate gyrus (dDG) in object recognition memory using a black box and object-context recognition memory using a clear box with available cues that define a spatial context. Based on a 10 min retention interval between the study phase and the test phase, the results indicated that dDG lesioned rats are impaired when compared to controls in the object-context recognition test in the clear box. However, there were no reliable differences between the dDG lesioned rats and the control group for the object recognition test in the black box. Even though the dDG lesioned rats were more active in object exploration, the habituation gradients did not differ. These results suggest that the dentate gyrus lesioned rats are clearly impaired when there is an important contribution of context. Furthermore, based on a 24 h retention interval in the black box the dDG lesioned rats were impaired compared to controls. PMID:23880567

  14. Critical role for the AIM2 inflammasome during acute central nervous system bacterial infection

    PubMed Central

    Hanamsagar, Richa; Aldrich, Amy; Kielian, Tammy

    2014-01-01

    Interleukin-1β (IL-1β) is essential for eliciting protective immunity during the acute phase of Staphylococcus aureus (S. aureus) infection in the central nervous system (CNS). We previously demonstrated that microglial IL-1β production in response to live S. aureus is mediated through the Nod-like receptor protein 3 (NLRP3) inflammasome, including the adapter protein ASC (apoptosis-associated, speck-like, caspase-1 recruiting domain-containing protein), and pro-caspase-1. Here we utilized NLRP3, ASC, and caspase-1/11 knockout (KO) mice to demonstrate the functional significance of inflammasome activity during CNS S. aureus infection. ASC and caspase-1/11 KO animals were exquisitely sensitive, with approximately 50% of mice succumbing to infection within 24 h. Unexpectedly, the survival of NLRP3 KO mice was similar to WT animals, suggesting the involvement of an alternative upstream sensor, which was later identified as absent in melanoma 2 (AIM2) based on the similar disease patterns between AIM2 and ASC KO mice. Besides IL-1β, other key inflammatory mediators, including IL-6, CXCL1, CXCL10, and CCL2 were significantly reduced in the CNS of AIM2 and ASC KO mice, implicating autocrine/paracrine actions of IL-1β, since these mediators do not require inflammasome processing for secretion. These studies demonstrate a novel role for the AIM2 inflammasome as a critical molecular platform for regulating IL-1β release and survival during acute CNS S. aureus infection. PMID:24484406

  15. When do objects become landmarks? A VR study of the effect of task relevance on spatial memory.

    PubMed

    Han, Xue; Byrne, Patrick; Kahana, Michael; Becker, Suzanna

    2012-01-01

    We investigated how objects come to serve as landmarks in spatial memory, and more specifically how they form part of an allocentric cognitive map. Participants performing a virtual driving task incidentally learned the layout of a virtual town and locations of objects in that town. They were subsequently tested on their spatial and recognition memory for the objects. To assess whether the objects were encoded allocentrically we examined pointing consistency across tested viewpoints. In three experiments, we found that spatial memory for objects at navigationally relevant locations was more consistent across tested viewpoints, particularly when participants had more limited experience of the environment. When participants' attention was focused on the appearance of objects, the navigational relevance effect was eliminated, whereas when their attention was focused on objects' locations, this effect was enhanced, supporting the hypothesis that when objects are processed in the service of navigation, rather than merely being viewed as objects, they engage qualitatively distinct attentional systems and are incorporated into an allocentric spatial representation. The results are consistent with evidence from the neuroimaging literature that when objects are relevant to navigation, they not only engage the ventral "object processing stream", but also the dorsal stream and medial temporal lobe memory system classically associated with allocentric spatial memory. PMID:22586455

  16. The Maintenance Of 3-D Scene Databases Using The Analytical Imagery Matching System (Aims)

    NASA Astrophysics Data System (ADS)

    Hovey, Stanford T.

    1987-06-01

    The increased demand for multi-resolution displays of simulated scene data for aircraft training or mission planning has led to a need for digital databases of 3-dimensional topography and geographically positioned objects. This data needs to be at varying resolutions or levels of detail as well as be positionally accurate to satisfy close-up and long distance scene views. The generation and maintenance processes for this type of digital database requires that relative and absolute spatial positions of geographic and cultural features be carefully controlled in order for the scenes to be representative and useful for simulation applications. Autometric, Incorporated has designed a modular Analytical Image Matching System (AIMS) which allows digital 3-D terrain feature data to be derived from cartographic and imagery sources by a combination of automatic and man-machine techniques. This system provides a means for superimposing the scenes of feature information in 3-D over imagery for updating. It also allows for real-time operator interaction between a monoscopic digital imagery display, a digital map display, a stereoscopic digital imagery display and automatically detected feature changes for transferring 3-D data from one coordinate system's frame of reference to another for updating the scene simulation database. It is an advanced, state-of-the-art means for implementing a modular, 3-D scene database maintenance capability, where original digital or converted-to-digital analog source imagery is used as a basic input to perform accurate updating.

  17. AHSME, AIME, USAMO: The Examinations of the Committee on High School Contests.

    ERIC Educational Resources Information Center

    Maurer, Stephen B.; Mientka, Walter E.

    1982-01-01

    Details are provided about the American High School Mathematics Examination (AHSME), the American Invitational Mathematics Examination (AIME), and the USA Mathematical Olympiad (USAMO). The AIME will first be offered in 1983 as an intermediate examination between the AHSME and the USAMO. An appendix provides several sample problems. (MP)

  18. Theoretical studies on 2-diazo-4,6-dinitrophenol derivatives aimed at finding superior propellants.

    PubMed

    Liu, Yan; Wang, Lianjun; Wang, Guixiang; Du, Hongchen; Gong, Xuedong

    2012-04-01

    In an attempt to find superior propellants, 2-diazo-4,6-dinitrophenol (DDNP) and its -NO(2), -NH(2), -CN, -NC, -ONO(2), and -NF(2) derivatives were studied at the B3LYP/6-311++G level of density functional theory (DFT). Sensitivity was evaluated using bond dissociation enthalpies (BDEs) and molecular surface electrostatic potentials. The C-NO(2) bond appears to be the trigger bond during the thermolysis process for these compounds, except for the -ONO(2) and -NF(2) derivatives. Electrostatic potential results show that electron-withdrawing substituents make the charge imbalance more anomalous, which may change the strength of the bond, especially the weakest trigger bond. Most of the DDNP derivatives have the impact sensitivities that are higher than that of DDNP, making them favorable for use as solid propellants in micro-rockets. The theoretical densities (ρ), heats of formation (HOFs), detonation energies (Q), detonation pressures (P), and detonation velocities (D) of the compounds were estimated. The effects of various substituent groups on ρ, HOF, Q, D, and P were investigated. Some derivatives exhibit perfect detonation properties. The calculated relative specific impulses (I (r,sp)) of all compounds except for -NH(2) derivatives were higher than that of DDNP, and also meet the requirements of propellants. PMID:21805131

  19. Qualification study of LiF flight crystals for the Objective Crystal Spectrometer on the SPECTRUM-X-GAMMA satellite

    NASA Astrophysics Data System (ADS)

    Christensen, F. E.; Rasmussen, I.; Schnopper, H. W.; Wiebicke, H.; Halm, I.; Geppert, U.; Borozdin, K.

    1992-10-01

    The Objective Crystal Spectrometer (OXS) on the SPECTRUM-X-GAMMA satellite will carry three types of natural crystals LiF(220), Ge(111) and RAP(001). They will be used to study, among others, the H- and the He-like emission from the cosmically important elements Fe, S, Ar and O. More than 300 LiF-crystals of dimension about 23 x 63 sq mm are required to cover one side of a large (about 1000 x 600 sq mm) panel which is to be mounted in front of one of the high throughput X-ray telescopes. A qualification study examined a large sample of LiF(220) crystals at Cu-K-(alpha)2 (8.0278 keV). Data from 124 flight crystals yields an average FWHM of rocking curves of 2.3 arcmin with a standard deviation of 0.4 arcmin. For more than 80 percent of the crystals, angular deviation of the (220) planes from the actual crystal surface is less than 1.5 arcmin. These data will be used to select the best crystals for the flight panel and will determine precisely the orientation of the crystals mounted on the OXS. Eight crystals were glued onto a small test panel of the OXS and for only one crystal was there measured a significant deviation of the crystal properties, including alignment relative to the others.

  20. Study of glycolaldehyde in a cosmic object

    NASA Astrophysics Data System (ADS)

    Sharma, Mohit

    2016-07-01

    Hollis {it et al.} (2004) detected glycolaldehyde towards the star-forming region Sgr B2(N) by means of 1_{1 0} - 1_{0 1}, 2_{1 1} - 2_{0 2}, 3_{1 2} - 3_{0 3} and 4_{1 3} - 4_{0 4} rotational transitions at 13.477, 15.176, 17.981 and 22.143 GHz, respectively. Halfen {it et al.} (2006) conducted a comprehensive study at 2 and 3 mm toward Sgr B2(N) and reported forty favourable transitions of glycolaldehyde in the range 68 - 169 GHz and determined its column density as 5.9 times 10^{13} cm^{-2}. First detection of glycolaldehyde outside the galactic center is reported by Beltran {it et al.} (2007). They reported detection of glycolaldehyde toward the hot molecular core G31.41+0.31 through the transitions 20_{2,18} - 19_{3,17}, 14_{0,14} - 13_{1,13} and 10_{1 9} - 9_{2 8} at 220.464, 143.641, 103.668 GHz, respectively. All of them are b-type transitions. The levels for b-type transitions can be classified into two groups: (i) with k_a + k_c = odd (set I) and (ii) with k_a + k_c = even (set II). For each of the sets I and II, we have calculated energies of 100 rotational levels. These levels are connected through radiative and collisional transitions. The Einstein A-coefficients for the radiative transitions among the levels are calculated. The collisional rate coefficients are calculated with the help of a scaling law. Using the radiative and collisional transitions probabilities, for each of the sets I and II, we have solved a set of statistical equilibrium equations coupled with the equations of radiative transfer. Two transitions 1_{1 0} - 1_{0 1} and 3_{1 2} - 3_{0 3} of set I, and one transition 2_{1 1} - 2_{0 2} of set II are found to have anomalous absorption. These transitions may play important role in the identification of glycolaldehyde in a cosmic object.

  1. The core legion object model

    SciTech Connect

    Lewis, M.; Grimshaw, A.

    1996-12-31

    The Legion project at the University of Virginia is an architecture for designing and building system services that provide the illusion of a single virtual machine to users, a virtual machine that provides secure shared object and shared name spaces, application adjustable fault-tolerance, improved response time, and greater throughput. Legion targets wide area assemblies of workstations, supercomputers, and parallel supercomputers, Legion tackles problems not solved by existing workstation based parallel processing tools; the system will enable fault-tolerance, wide area parallel processing, inter-operability, heterogeneity, a single global name space, protection, security, efficient scheduling, and comprehensive resource management. This paper describes the core Legion object model, which specifies the composition and functionality of Legion`s core objects-those objects that cooperate to create, locate, manage, and remove objects in the Legion system. The object model facilitates a flexible extensible implementation, provides a single global name space, grants site autonomy to participating organizations, and scales to millions of sites and trillions of objects.

  2. The Robust Weighted Multi-Objective Game

    PubMed Central

    2015-01-01

    This paper studies a class of multi-objective n-person non-zero sum games through a robust weighted approach where each player has more than one competing objective. This robust weighted multi-objective game model assumes that each player attaches a set of weights to its objectives instead of accessing accurate weights. Each player wishes to minimize its maximum weighted sum objective where the maximization is pointing to the set of weights. To address this new model, a new equilibrium concept-robust weighted Nash equilibrium is obtained. The existence of this new concept is proven on suitable assumptions about the multi-objective payoffs. PMID:26406986

  3. The Tourette International Collaborative Genetics (TIC Genetics) study, finding the genes causing Tourette syndrome: objectives and methods.

    PubMed

    Dietrich, Andrea; Fernandez, Thomas V; King, Robert A; State, Matthew W; Tischfield, Jay A; Hoekstra, Pieter J; Heiman, Gary A

    2015-02-01

    Tourette syndrome (TS) is a neuropsychiatric disorder characterized by recurrent motor and vocal tics, often accompanied by obsessive-compulsive disorder and/or attention-deficit/hyperactivity disorder. While the evidence for a genetic contribution is strong, its exact nature has yet to be clarified fully. There is now mounting evidence that the genetic risks for TS include both common and rare variants and may involve complex multigenic inheritance or, in rare cases, a single major gene. Based on recent progress in many other common disorders with apparently similar genetic architectures, it is clear that large patient cohorts and open-access repositories will be essential to further advance the field. To that end, the large multicenter Tourette International Collaborative Genetics (TIC Genetics) study was established. The goal of the TIC Genetics study is to undertake a comprehensive gene discovery effort, focusing both on familial genetic variants with large effects within multiply affected pedigrees and on de novo mutations ascertained through the analysis of apparently simplex parent-child trios with non-familial tics. The clinical data and biomaterials (DNA, transformed cell lines, RNA) are part of a sharing repository located within the National Institute for Mental Health Center for Collaborative Genomics Research on Mental Disorders, USA, and will be made available to the broad scientific community. This resource will ultimately facilitate better understanding of the pathophysiology of TS and related disorders and the development of novel therapies. Here, we describe the objectives and methods of the TIC Genetics study as a reference for future studies from our group and to facilitate collaboration between genetics consortia in the field of TS. PMID:24771252

  4. Diurnal rhythm and concordance between objective and subjective hot flashes: The Hilo Women’s Health Study

    PubMed Central

    Sievert, Lynnette L.; Reza, Angela; Mills, Phoebe; Morrison, Lynn; Rahberg, Nichole; Goodloe, Amber; Sutherland, Michael; Brown, Daniel E.

    2010-01-01

    Objective To test for a diurnal pattern in hot flashes in a multi-ethnic population living in a hot, humid environment. To examine rates of concordance between objective and subjective measures of hot flashes using ambulatory and laboratory measures. Methods Study participants aged 45–55 were recruited from the general population of Hilo, Hawaii. Women wore a Biolog hot flash monitor, kept a diary for 24-hours, and also participated in 3-hour laboratory measures (n=199). Diurnal patterns were assessed using polynomial regression. For each woman, objectively recorded hot flashes that matched subjective experience were treated as true positive readings. Subjective hot flashes were considered the standard for computing false positive and false negative readings. True positive, false positive, and false negative readings were compared across ethnic groups by chi-square analyses. Results Frequencies of sternal, nuchal and subjective hot flashes peaked at 15:00 ± 1 hour with no difference by ethnicity. Laboratory results supported the pattern seen in ambulatory monitoring. Sternal and nuchal monitoring showed the same frequency of true positive measures, but non-sternal electrodes picked up more false positive readings. Laboratory monitoring showed very low frequencies of false negatives. There were no ethnic differences in the frequency of true positive or false positive measures. Women of European descent were more likely to report hot flashes that were not objectively demonstrated (false negative measures). Conclusions The diurnal pattern and peak in hot flash occurrence in the hot humid environment of Hilo was similar to results from more temperate environments. Lack of variation in sternal vs. non-sternal measures, and in true positive measures across ethnicities suggests no appreciable effect of population variation in sweating patterns. PMID:20220538

  5. The ROSSI X-Ray Timing Explorer: Capabilities, Achievements and Aims

    NASA Technical Reports Server (NTRS)

    Swank, J. H.

    2007-01-01

    The prime scientific objectives of the Rossi X-Ray Timing Explorer (RXTE) were the study of astrophysical compact objects: black holes (galactic and extragalactic), many types of neutron stars, and accreting white dwarfs. RXTE was successful in achieving its original observing objectives of large area and high time resolution observations with broadband (2-200 keV) spectra, scheduled flexibly enough to enable observations of targets of opportunity on any timescale greater than a few hours. These capabilities enabled qualitatively new discoveries about dynamical timescale phenomena related to neutron stars and black holes, phenomena which probe basic physics in the most extreme environments of gravity, density, and magnetic fields. RXTE has extended its lifetime by applying the proportional counter area selectively and maintains schedule flexibility by making use of the distribution of targets around the sky. Proposed future observations emphasize opportunity to discover and study additional millisecond pulsars, pursue the high frequency quasi-periodic oscillations in black hole transients, and connect high frequency phenomena with longer term characteristics. RXTE will continue to strongly support, for both galactic and extragalactic targets, combining RXTE observations with other wavelengths (from IR to TeV) or with other capabilities, such as high spectral resolution.

  6. Is Objectively Measured Sitting Time Associated with Low Back Pain? A Cross-Sectional Investigation in the NOMAD study

    PubMed Central

    Gupta, Nidhi; Christiansen, Caroline Stordal; Hallman, David M.; Korshøj, Mette; Carneiro, Isabella Gomes; Holtermann, Andreas

    2015-01-01

    Background Studies on the association between sitting time and low back pain (LBP) have found contrasting results. This may be due to the lack of objectively measured sitting time or because socioeconomic confounders were not considered in the analysis. Objectives To investigate the association between objectively measured sitting time (daily total, and occupational and leisure-time periods) and LBP among blue-collar workers. Methods Two-hundred-and-one blue-collar workers wore two accelerometers (GT3X+ Actigraph) for up to four consecutive working days to obtain objective measures of sitting time, estimated via Acti4 software. Workers reported their LBP intensity the past month on a scale from 0 (no pain) to 9 (worst imaginable pain) and were categorized into either low (≤5) or high (>5) LBP intensity groups. In the multivariate-adjusted binary logistic regression analysis, total sitting time, and occupational and leisure-time sitting were both modeled as continuous (hours/day) and categorical variables (i.e. low, moderate and high sitting time). Results The multivariate logistic regression analysis showed a significant positive association between total sitting time (per hour) and high LBP intensity (odds ratio; OR=1.43, 95%CI=1.15-1.77, P=0.01). Similar results were obtained for leisure-time sitting (OR=1.45, 95%CI=1.10-1.91, P=0.01), and a similar but non-significant trend was obtained for occupational sitting time (OR=1.34, 95%CI 0.99-1.82, P=0.06). In the analysis on categorized sitting time, high sitting time was positively associated with high LBP for total (OR=3.31, 95%CI=1.18-9.28, P=0.03), leisure (OR=5.31, 95%CI=1.57-17.90, P=0.01), and occupational (OR=3.26, 95%CI=0.89-11.98, P=0.08) periods, referencing those with low sitting time. Conclusion Sitting time is positively associated with LBP intensity among blue-collar workers. Future studies using a prospective design with objective measures of sitting time are recommended. PMID:25806808

  7. Surgical Outcome in Patients Taking Concomitant or Recent Intake of Oral Isotretinoin: A Multicentric Study-ISO-AIMS Study

    PubMed Central

    Mahadevappa, Omprakash Heggadahalli; Mysore, Venkataram; Viswanath, Vishalakshi; Thurakkal, Salim; Majid, Imran; Talwar, Suresh; Aurangabadkar, Sanjeev J; Chatterjee, Manas; Bhat, M Ramesh; Barua, Shyamanta; Ganjoo, Anil

    2016-01-01

    Background: The current standard recommendation is to avoid surgical interventions in patients taking oral isotretinoin. However, this recommendation has been questioned in several recent publications. Aim: To document the safety of cosmetic and surgical interventions, among patients receiving or recently received oral isotretinoin. Materials and Methods: Association of Cutaneous Surgeons, India, in May 2012, initiated this study, at 11 centers in different parts of India. The data of 183 cases were collected monthly, from June 2012 to May 2013. Of these 61 patients had stopped oral isotretinoin before surgery and 122 were concomitantly taking oral isotretinoin during the study period. In these 183 patients, a total of 504 interventions were performed. These included[1] 246 sessions of chemical peels such as glycolic acid, salicylic acid, trichloroacetic acid, and combination peels;[2] 158 sessions of lasers such as ablative fractional laser resurfacing with erbium-doped yttrium aluminum garnet and CO2, conventional full face CO2 laser resurfacing, laser-assisted hair reduction with long-pulsed neodymium-doped yttrium aluminum garnet, diode laser, and LASIK surgery;[3] 27 sessions of cold steel surgeries such as microneedling, skin biopsy, subcision, punch elevation of scars, excision of skin lesion, and wisdom tooth extraction;[4] 1 session of electrosurgery. Results: No significant side effects were noted in most patients. 2 cases of keloid were documented which amounted to 0.4% of side effects in 504 interventions, with a significant P value of 0.000. Reversible transient side effects were erythema in 10 interventions and hyperpigmentation in 15. Conclusion: The study showed that performing dermatosurgical and laser procedures in patients receiving or recently received isotretinoin is safe, and the current guidelines of avoiding dermatosurgical and laser interventions in such patients taking isotretinoin need to be revised. PMID:27398012

  8. COPD Multidisciplinary Team Meetings in the United Kingdom: Health Care Professionals' Perceptions of Aims and Structure.

    PubMed

    Kruis, Annemarije L; Soljak, Michael; Chavannes, Niels H; Elkin, Sarah L

    2016-10-01

    Over the last 10 years, community and hospital-based multidisciplinary teams (MDTs) have been set up for the management of patients with chronic obstructive pulmonary disease (COPD) in the UK. Meetings of the MDTs have become a regular occurrence, mostly on healthcare professionals' own initiatives. There are no standardized methods to conduct an MDT meeting, and although cancer MDT meetings are widely implemented, the value and purpose of COPD MDT meetings are less clear. Therefore, the aim of this study was to conduct a cross-sectional descriptive online survey to explore COPD MDT members' perceptions of the purpose and usefulness of MDT meetings, and to identify suggestions or requirements to improve the meetings. In total, we received 68 responses from 10 MDTs; six teams (n = 36 members) were located in London and four (n = 32 members) outside. Analysis of the replies by two independent researchers found that MDT meetings aim to optimise management and improve pathways for respiratory patients by improving communication between providers across settings and disciplines. Education of the MDT members also occurs with the aim of safer practice. Discussed patients are characterised by (multiple) co-morbidities, frequent exacerbations and admissions, social and mental health problems, unclear diagnosis and suboptimal responses to interventions. Members reported participating in a COPD MDT as very useful (74%) or useful (20%). Meetings could be improved by ensuring attendance through requirement in job plans, by clear documentation and sharing of derived plans with a wider audience including general practitioners and patients. PMID:26263193

  9. Does visual working memory represent the predicted locations of future target objects? An event-related brain potential study.

    PubMed

    Grubert, Anna; Eimer, Martin

    2015-11-11

    During the maintenance of task-relevant objects in visual working memory, the contralateral delay activity (CDA) is elicited over the hemisphere opposite to the visual field where these objects are presented. The presence of this lateralised CDA component demonstrates the existence of position-dependent object representations in working memory. We employed a change detection task to investigate whether the represented object locations in visual working memory are shifted in preparation for the known location of upcoming comparison stimuli. On each trial, bilateral memory displays were followed after a delay period by bilateral test displays. Participants had to encode and maintain three visual objects on one side of the memory display, and to judge whether they were identical or different to three objects in the test display. Task-relevant memory and test stimuli were located in the same visual hemifield in the no-shift task, and on opposite sides in the horizontal shift task. CDA components of similar size were triggered contralateral to the memorized objects in both tasks. The absence of a polarity reversal of the CDA in the horizontal shift task demonstrated that there was no preparatory shift of memorized object location towards the side of the upcoming comparison stimuli. These results suggest that visual working memory represents the locations of visual objects during encoding, and that the matching of memorized and test objects at different locations is based on a comparison process that can bridge spatial translations between these objects. This article is part of a Special Issue entitled SI: Prediction and Attention. PMID:25445999

  10. Social Studies: 1970; Instructional Objectives for Grades 1-8.

    ERIC Educational Resources Information Center

    Catholic School Board, Chicago, IL.

    The objectives of this curriculum guide for teachers are: 1) to provide a unified list of yearly instructional objectives for each social studies classroom; 2) to provide basic standards for measuring pupil progress; and 3) to provide a guide for the continuous development in the social studies. The recommendations for each grade level cover:…

  11. From Triple to Quadruple Aim: Care of the Patient Requires Care of the Provider

    PubMed Central

    Bodenheimer, Thomas; Sinsky, Christine

    2014-01-01

    The Triple Aim—enhancing patient experience, improving population health, and reducing costs—is widely accepted as a compass to optimize health system performance. Yet physicians and other members of the health care workforce report widespread burnout and dissatisfaction. Burnout is associated with lower patient satisfaction, reduced health outcomes, and it may increase costs. Burnout thus imperils the Triple Aim. This article recommends that the Triple Aim be expanded to a Quadruple Aim, adding the goal of improving the work life of health care providers, including clinicians and staff. PMID:25384822

  12. Thyroid and Pregnancy in Tehran, Iran: Objectives and Study Protocol

    PubMed Central

    Nazarpour, Sima; Ramezani Tehrani, Fahimeh; Simbar, Masoumeh; Tohidi, Maryam; Azizi, Fereidoun

    2016-01-01

    Background Thyroid dysfunction is the second most common endocrine disease in females of reproductive age. There are controversial data on the adverse effect of subclinical thyroid dysfunctions on adverse feto-maternal outcomes. Objectives The current study aimed to identify the prevalence of thyroid dysfunction during pregnancy and to assess the effectiveness of treatment with levothyroxine on pregnancy outcomes of females with thyroid autoimmunity with or without subclinical thyroid dysfunction in Tehran, Iran. Patients and Methods The study encompassed two phases: 1) a population based cross sectional study using a cluster sampling method that screened first trimester pregnant females for thyroid disorders, 2) a double-blind randomized clinical trial to determine the effectiveness of levothyroxine on adverse pregnancy outcomes in females with thyroid autoimmunity with or without subclinical thyroid dysfunction. Pregnant females were assessed at their first prenatal visit for serum TSH, T4, T-uptake, TPOAb and urinary iodine following which they were classified as: 1) normal, 2) subclinical TPOAb negative and 3) subclinical/euthyroid TPOAb positive. Females in groups two and three were randomly divided into two groups: group A was treated with levothyroxine (LT4), and group B did not receive any treatment. There was a follow-up program for participants and rates of adverse pregnancy outcomes in the treated and untreated groups were measured. Results Results of the study provided reliable information regarding the prevalence of thyroid dysfunction among females in Tehran using universal thyroid screening, along with identification of the iodine status of their community. The study aimed to determine whether LT4 treatment exerts beneficial effects in females without overt thyroid dysfunction. PMID:27279833

  13. The Scattered Kuiper Belt Objects

    NASA Astrophysics Data System (ADS)

    Trujillo, C. A.; Jewitt, D. C.; Luu, J. X.

    1999-09-01

    We describe a continuing survey of the Kuiper Belt conducted at the 3.6-m Canada France Hawaii Telescope on Mauna Kea, Hawaii. The survey employs a 12288 x 8192 pixel CCD mosaic to image the sky to red magnitude 24. All detected objects are targeted for systematic follow-up observations, allowing us to determine their orbital characteristics. Three new members of the rare Scattered Kuiper Belt Object class have been identified, bringing the known population of such objects to four. The SKBOs are thought to have been scattered outward by Neptune, and are a potential source of the short-period comets. Using a Maximum Likelihood method, we place observational constraints on the total number and mass of the SKBOs.

  14. Ground-Based Near-Earth Object Studies in the post-Russian (Chelyabinsk) Meteor Airburst World

    NASA Astrophysics Data System (ADS)

    Ryan, E.; Ryan, W. H.

    2013-09-01

    Public awareness of the danger of potentially hazardous asteroids has been heightened by the airburst of a meteor over Chelyabinsk, Russia, on February 15, 2013, which caused millions of dollars in damage from a shock wave that impacted structures and injured ~1500 people. Later that same day, a larger asteroid, 2012 DA14, made a close approach to the Earth, but harmlessly skimmed past. Further, other very close-approaching Near-Earth objects (NEOs) have recently posed threats to man-made space assets by passing through or very near the geosynchronous satellite zone. These events have lead to increased awareness and concern, and have subsequently served as a catalyst for deeper exploration of what is being done to mitigate such hazards, and whether more effort needs to be placed in this area of study. An NEO is designated as "potentially hazardous" when its orbit comes to within 0.05 AU of the Earth's orbit. Ground-based physical characterization studies of Near-Earth Objects (NEOs) that are cataloged as potentially hazardous objects (PHOs) are very beneficial to any mitigation plan that might be devised if the risk of impact is high. After a well-defined orbit has been determined for a PHO, other physical parameters such as size, rotation rate, and composition are important. For the smallest PHOs being discovered, observational efforts must commence at or near the time of discovery to ensure favorable parameters for data collection. Otherwise, subsequent optimal apparitions for observing an asteroid or comet may be decades away. Researchers at the Magdalena Ridge Observatory (MRO) 2.4-meter telescope facility are well positioned to acquire real-time physical information on PHOs since their ongoing NEO follow-up and characterization program collects data monthly throughout the year on the smallest, close-approaching NEOs being discovered. Over the past 5 years that this program has been in operation, spin rates for over 50 Near-Earth asteroids have been obtained

  15. Hormonal regulation of capillary fenestrae in the rat adrenal cortex: quantitative studies using objective lens staging scanning electron microscopy.

    PubMed

    Apkarian, R P; Curtis, J C

    1986-01-01

    High magnification studies of the fenestrated capillary endothelium in the zona fasciculata (ZF) of rat adrenal glands were performed using the objective lens stage of an analytical scanning electron microscope (SEM) equipped with a lanthanum hexaboride emitter (LaB6). Resolution of surface substructure of the luminal membrane obtained with specimens decorated with gold/palladium (Au/Pd) was compared with that observed in others sputter coated with tantalum (Ta). High magnification (50,000x) of the fenestrated endothelium demonstrates that tantalum coating of the cryofractured adrenals improves the substructural detail compared to that seen in Au/Pd decorated specimens. The procedures used in specimen preparation, metal deposition and secondary electron imaging (SEI) are described. Quality imaging achieved using the objective lens stage is a result of the elimination of the SE-III component derived from backscattered electrons. Rat adrenals exhibited uniformly patent capillaries. High magnification micrographs of capillary walls were randomly recorded in two morphometric studies of the fenestral content of capillaries in the rat adrenal cortex. Adrenocorticotropic hormone (ACTH), when administered to rats following dexamethasone (DEX) treatment, significantly reduced the fenestrae/micron 2 of endothelial surface and increased the mean size of fenestrae. After hypophysectomy, the number of fenestrae/micron 2 declined over 48 h; within 2 h after ACTH was given to rats hypophysectomized 48 hours earlier, the fenestrae/micron 2 had increased two-fold. These studies indicate that ACTH plays an important role in modulating fenestral content of the capillary endothelium in the adrenal cortex. PMID:3027881

  16. A study of the structure and kinematics of the narrow-line region in Seyfert galaxies. III. Individual objects

    SciTech Connect

    Veilleux, S. )

    1991-03-01

    An individual analysis is presented of the narrow-line profiles of 16 Seyfert galaxies. Substructure is observed in all but one of the sample objects. A direct relationship between the radio structure and these emission-line components is proposed in about half of the objects. The emission-line components generally have flux ratios which are quite similar to the rest of the narrow-line gas. These results suggest that the radio-emitting plasma strongly affects the kinematics of the thermal gas of the narrow-line region (NLR), but not its ionization state. Evidence for ionization/density stratification of the gas in the NLR is found in 4(ionization)/5(density) of the 11 objects for which a multispecies analysis is possible. The stronger cases of stratification are found in the objects whose emission lines present a minimum of profile substructure. A multicomponent model of the NLR is proposed to explain the results of this paper and previous ones. 192 refs.

  17. Small is beautiful but smaller is the aim: review of a life of research.

    PubMed

    Curtis, A S G

    2004-01-01

    Background and origins of research of Adam Curtis. One persisting theme has been the pursuit of different landscapes at different scales to discover the routes to explain how the body is built. His research life fell in a fortunate period during which techniques and concepts for investigating structure have improved year by year. His most fortunate encounter was with Michael Abercrombie and his views on the social behaviour of cells, aims for quantitation, and statistical testing. Adam worked in various environments--in turn Geology as an undergraduate, Biophysics Ph.D. in a Genetics department and various departments in turn from anatomy via zoology to Cell Biology. Adam started his Ph.D. work in cell adhesion, studying cell movement, trapping and reaggregation phenomena, having an early start from the physico-chemical viewpoint. He made quantitative measurements of cell adhesion by kinetic methods. Interference reflection microscopy (IRM) and related optical interference techniques were brought into the field of biology by him. In turn this led with Chris Wilkinson, a long term colleague, to the use of micro- and nanofabrication for biological research. Polscope and photoelastic measurements were introduced to biology recently in his laboratory. One long term theme has been to map the adhesion of cells to substrates to discover contact areas. Early data came from IRM and then TIRF (Total Internal Reflection Fluorescence Microscopy) and then from Forster Resonance Energy Microscopy (FRET). Another important theme was the time scale that needed to be measured--very short indeed in suspension. This was very difficult and has only become possible very recently but hydrodynamic calculation shows it must be very short. The attractions of the Derjagin-Landau-Verwey-Overbeek theory (DLVO theory) are that they explain many features of biological adhesion. The main test of this theory depends upon the energy of the adhesion at various different separation distances between

  18. Spectral reflectance properties of major objects in desert oasis: a case study of the Weigan-Kuqa river delta oasis in Xinjiang, China.

    PubMed

    Zhang, Fei; Tiyip, Tashpolat; Ding, Jianli; Sawut, Mamat; Tashpolat, Nigara; Kung, Hsiangte; Han, Guihong; Gui, Dongwei

    2012-08-01

    Aiming at the remote sensing application has been increasingly relying on ground object spectral characteristics. In order to further research the spectral reflectance characteristics in arid area, this study was performed in the typical delta oasis of Weigan and Kuqa rivers located north of Tarim Basin. Data were collected from geo-targets at multiple sites in various field conditions. The spectra data were collected for different soil types including saline-alkaline soil, silt sandy soil, cotton field, and others; vegetations of Alhagi sparsifolia, Phragmites australis, Tamarix, Halostachys caspica, etc., and water bodies. Next, the data were processed to remove high-frequency noise, and the spectral curves were smoothed with the moving average method. The derivative spectrum was generated after eliminating environmental background noise so that to distinguish the original overlap spectra. After continuum removal of the undesirable absorbance, the spectrum curves were able to highlight features for both optical absorbance and reflectance. The spectrum information of each ground object is essential for fully utilizing the multispectrum data generated by remote sensing, which will need a representative spectral library. In this study using ENVI 4.5 software, a preliminary spectral library of surface features was constructed using the data surveyed in the study area. This library can support remote sensing activities such as feature investigation, vegetation classification, and environmental monitoring in the delta oasis region. Future plan will focus on sharing and standardizing the criteria of professional spectral library and to expand and promote the utilization of the spectral databases. PMID:21922179

  19. Correlates of objectively assessed physical activity and sedentary time in children: a cross-sectional study (The European Youth Heart Study)

    PubMed Central

    2009-01-01

    Background Identifying leisure time activities performed before and after school that influence time in physical activity (PA) and/or time spent sedentary can provide useful information when designing interventions aimed to promote an active lifestyle in young people. The purpose of this study was to examine associations between mode of transportation to school, outdoor play after school, participation in exercise in clubs, and TV viewing with objectively assessed PA and sedentary behaviour in children. Methods A total of 1327 nine- and 15-year-old children from three European countries (Norway, Estonia, Portugal) participated as part of the European Youth Heart Study. PA was measured during two weekdays and two weekend days using the MTI accelerometer, and average percent of time in moderate-to-vigorous PA (MVPA) and time spent sedentary were derived. Potential correlates were assessed by self-report. Independent associations between self-reported correlates with percent time in MVPA and percent time sedentary were analysed by general linear models, adjusted by age, gender, country, measurement period, monitored days and parental socio-economic status. Results In 9-year-olds, playing outdoors after school was associated with higher percent time in MVPA (P < 0.01), while participation in sport clubs was associated with higher percent time in MVPA (P < 0.01) in 15-year-olds. No associations with percent time sedentary were observed in either age group. Conclusion Frequency of outdoor play after school is a significant correlate for daily time in MVPA in 9-year-olds, while this correlate is attenuated in favour of participation in sport and exercise in clubs in 15-year-olds. Targeting walking to school or reduced TV viewing time in order to increase time in daily MVPA in children is unlikely to be sufficient. Correlates related to time spent sedentary need further examination. PMID:19735565

  20. Do Children with ASD Use Referential Gaze to Learn the Name of an Object? An Eye-Tracking Study

    ERIC Educational Resources Information Center

    Akechi, Hironori; Senju, Atsushi; Kikuchi, Yukiko; Tojo, Yoshikuni; Osanai, Hiroo; Hasegawa, Toshikazu

    2011-01-01

    Children with autism spectrum disorder (ASD) are reported to have difficulty in learning novel word-object associations in case of discrepancy between objects in the speaker's focus and their focus (the discrepant condition). Two eye-tracking experiments investigated this difficulty by controlling and recording children's gaze fixation. In…

  1. Double Object Constructions in L3 English: An Exploratory Study of Morphological and Semantic Constraints

    ERIC Educational Resources Information Center

    Agirre, Ainara Imaz; García Mayo, María del Pilar

    2014-01-01

    The present study examines the acquisition of double object constructions (DOCs) ("Susan gave Peter an apple") by 90 Basque/Spanish learners of English as a third language (L3). The aim of this study was to explore whether (i) learners established a distinction when accepting DOCs vs. prepositional phrase constructions (PPCs)…

  2. Electronic and thermal transport study of sinusoidally corrugated nanowires aiming to improve thermoelectric efficiency.

    PubMed

    Park, K H; Martin, P N; Ravaioli, U

    2016-01-22

    Improvement of thermoelectric efficiency has been very challenging in the solid-state industry due to the interplay among transport coefficients which measure the efficiency. In this work, we modulate the geometry of nanowires to interrupt thermal transport with causing only a minimal impact on electronic transport properties, thereby maximizing the thermoelectric power generation. As it is essential to scrutinize comprehensively both electronic and thermal transport behaviors for nano-scale thermoelectric devices, we investigate the Seebeck coefficient, the electrical conductance, and the thermal conductivity of sinusoidally corrugated silicon nanowires and eventually look into an enhancement of the thermoelectric figure-of-merit [Formula: see text] from the modulated nanowires over typical straight nanowires. A loss in the electronic transport coefficient is calculated with the recursive Green function along with the Landauer formalism, and the thermal transport is simulated with the molecular dynamics. In contrast to a small influence on the thermopower and the electrical conductance of the geometry-modulated nanowires, a large reduction of the thermal conductivity yields an enhancement of the efficiency by 10% to 35% from the typical nanowires. We find that this approach can be easily extended to various structures and materials as we consider the geometrical modulation as a sole source of perturbation to the system. PMID:26650977

  3. The association between objectively measured physical activity and academic achievement in Dutch adolescents: findings from the GOALS study.

    PubMed

    Van Dijk, Martin L; De Groot, Renate H; Savelberg, Hans H; Van Acker, Frederik; Kirschner, Paul A

    2014-10-01

    The main goal of this study was to investigate the association between objectively measured physical activity and academic achievement in adolescents. Students in Grades 7 and 9 (N = 255) were included. Overall, we found no significant dose-response association between physical activity and academic achievement. However, in Grade 7 total physical activity volume (Total PA) was negatively associated with academic achievement, while moderate-to-vigorous intensity physical activity (MVPA) was negatively associated with both academic achievement and mathematics performance. In contrast, in Grade 9 both Total PA and MVPA were positively associated with mathematics performance. In addition, the overall association between MVPA and academic achievement followed an inverted U-shaped curve. Finally, Total PA was positively associated with executive functioning, while executive functioning in turn mediated the associations between Total PA and both academic achievement and mathematics performance. These results indicate that the association between physical activity and academic achievement in adolescents is complex and might be affected by academic year, physical activity volume and intensity, and school grade. PMID:25356610

  4. The Core of Religious Education: Finnish Student Teachers' Pedagogical Aims

    ERIC Educational Resources Information Center

    Kuusisto, Elina; Tirri, Kirsi

    2014-01-01

    This article investigated the core of religious education (RE) by examining Finnish student teachers' pedagogical aims in the context of Lutheran RE. The data consisted of essays (N=82) analysed in a deductive manner using the main concepts of the didactic triangle together with the aims of the Finnish National Core Curriculum. The student…

  5. Strength of object representation: its key role in object-based attention for determining the competition result between Gestalt and top-down objects.

    PubMed

    Zhao, Jingjing; Wang, Yonghui; Liu, Donglai; Zhao, Liang; Liu, Peng

    2015-10-01

    It was found in previous studies that two types of objects (rectangles formed according to the Gestalt principle and Chinese words formed in a top-down fashion) can both induce an object-based effect. The aim of the present study was to investigate how the strength of an object representation affects the result of the competition between these two types of objects based on research carried out by Liu, Wang and Zhou [(2011) Acta Psychologica, 138(3), 397-404]. In Experiment 1, the rectangles were filled with two different colors to increase the strength of Gestalt object representation, and we found that the object effect changed significantly for the different stimulus types. Experiment 2 used Chinese words with various familiarities to manipulate the strength of the top-down object representation. As a result, the object-based effect induced by rectangles was observed only when the Chinese word familiarity was low. These results suggest that the strength of object representation determines the result of competition between different types of objects. PMID:26041271

  6. A matched pair cluster randomized implementation trail to measure the effectiveness of an intervention package aiming to decrease perinatal mortality and increase institution-based obstetric care among indigenous women in Guatemala: study protocol

    PubMed Central

    2013-01-01

    Background Maternal and perinatal mortality continue to be a high priority problem on the health agendas of less developed countries. Despite the progress made in the last decade to quantify the magnitude of maternal mortality, few interventions have been implemented with the intent to measure impact directly on maternal or perinatal deaths. The success of interventions implemented in less developed countries to reduce mortality has been questioned, in terms of the tendency to maintain a clinical perspective with a focus on purely medical care separate from community-based approaches that take cultural and social aspects of maternal and perinatal deaths into account. Our innovative approach utilizes both the clinical and community perspectives; moreover, our study will report the weight that each of these components may have had on reducing perinatal mortality and increasing institution-based deliveries. Methods/Design A matched pair cluster-randomized trial will be conducted in clinics in four rural indigenous districts with the highest maternal mortality ratios in Guatemala. The individual clinic will serve as the unit of randomization, with 15 matched pairs of control and intervention clinics composing the final sample. Three interventions will be implemented in indigenous, rural and poor populations: a simulation training program for emergency obstetric and perinatal care, increased participation of the professional midwife in strengthening the link between traditional birth attendants (TBA) and the formal health care system, and a social marketing campaign to promote institution-based deliveries. No external intervention is planned for control clinics, although enhanced monitoring, surveillance and data collection will occur throughout the study in all clinics throughout the four districts. All obstetric events occurring in any of the participating health facilities and districts during the 18 months implementation period will be included in the analysis

  7. Revisiting the Genetic Ancestry of Brazilians Using Autosomal AIM-Indels

    PubMed Central

    Saloum de Neves Manta, Fernanda; Pereira, Rui; Vianna, Romulo; Rodolfo Beuttenmüller de Araújo, Alfredo; Leite Góes Gitaí, Daniel; Aparecida da Silva, Dayse; de Vargas Wolfgramm, Eldamária; da Mota Pontes, Isabel; Ivan Aguiar, José; Ozório Moraes, Milton; Fagundes de Carvalho, Elizeu; Gusmão, Leonor

    2013-01-01

    There are many different studies that contribute to the global picture of the ethnic heterogeneity in Brazilian populations. These studies use different types of genetic markers and are focused on the comparison of populations at different levels. In some of them, each geographical region is treated as a single homogeneous population, whereas other studies create different subdivisions: political (e.g., pooling populations by State), demographic (e.g., urban and rural), or ethnic (e.g., culture, self-declaration, or skin colour). In this study, we performed an enhanced reassessment of the genetic ancestry of ~ 1,300 Brazilians characterised for 46 autosomal Ancestry Informative Markers (AIMs). In addition, 798 individuals from twelve Brazilian populations representing the five geographical macro-regions of Brazil were newly genotyped, including a Native American community and a rural Amazonian community. Following an increasing North to South gradient, European ancestry was the most prevalent in all urban populations (with values up to 74%). The populations in the North consisted of a significant proportion of Native American ancestry that was about two times higher than the African contribution. Conversely, in the Northeast, Center-West and Southeast, African ancestry was the second most prevalent. At an intrapopulation level, all urban populations were highly admixed, and most of the variation in ancestry proportions was observed between individuals within each population rather than among population. Nevertheless, individuals with a high proportion of Native American ancestry are only found in the samples from Terena and Santa Isabel. Our results allowed us to further refine the genetic landscape of Brazilians while establishing the basis for the effective application of an autosomal AIM panel in forensic casework and clinical association studies within the highly admixed Brazilian populations. PMID:24073242

  8. Romanian ancient gold objects provenance studies using micro-beam methods: the case of “Pietroasa” hoard

    NASA Astrophysics Data System (ADS)

    Constantinescu, B.; Bugoi, R.; Cojocaru, V.; Voiculescu, D.; Grambole, D.; Herrmann, F.; Ceccato, D.

    2005-04-01

    Five fragments of ancient gold objects belonging to Pietroasa "Cloşca cu Puii de Aur" ("The Golden Brood Hen with Its Chickens") Romanian hoard were analysed using the micro-PIXE (particle induced X-ray emission) technique. The purpose of the study was to gain some more knowledge regarding the metal provenance by determining the presence of PGE (Platinum Group Elements) and other high-temperature melting point trace elements (Ta, Nb, Cr) at a micrometric scale. Ta and Nb inclusions (micrometric areas of composition different from the surroundings) on three samples and Pd inclusions on one sample were found. The measurements led to some conclusions for the possible gold ore sources of Pietroasa treasury: the South-Ural Mountains, Nubia (Sudan) and/or Anatolian deposits and Roman imperial coins.

  9. Study of the Surface Heterogeneity of icy dwarf?planets and other medium size Kuiper Belt objects

    NASA Astrophysics Data System (ADS)

    Pinilla-Alonso, Noemi; Emery, Josh P.

    2015-10-01

    We propose a comprehensive analysis of the surface heterogeneity of a selected sample of dwarf-planets and candidates to be considered as dwarf-planets. The sample has been carefully selected to reach the scientific goals with a relative low cost in observing time. The research proposed here will be based on the analysis of the light-curve of these objects obtained using IRAC/Spitzer photometry. KBOs likely retain some of the most primitive material in the Solar System. Models of the retention of volatiles by small-bodies in the Solar System show that dwarf-planets can retain most of the original inventory of volatiles. A good example is Pluto. The surface of this body is formed by patches of CH4, N2 and CO and exhibits a large degree of surface heterogeneity. Our preliminary results of the IRAC/Spitzer light curves of Pluto, obtained by this group in 2004 and 2014, show the potential of these data to map the surface distribution of the different species of ices on the surface of KBOs. For this project we have selected six objects (out of a list of 15) that are ideal for this study using Spitzer photometry. Our sample covers two classes of bodies: Eris, Makemake and Haumea, all large enough to retain volatiles and so how signs of sublimation and condensation cycles on their surfaces; and Quaoar, Varuna and Ixion (D<1000 km) that may not have retained volatiles. If signs of heterogeneity are detected on IRAC data from these medium bodies (as suggested by previous studies) this could be due to a combination of collisions and irradiation. By addressing the compositional heterogeneity of this sample of KBOs the proposed work will address gaps in the scientific knowledge of the chemical and dynamical history of the outer Solar System as well as other planetary systems.}

  10. Representing and Extracting Lung Cancer Study Metadata: Study Objective and Study Design

    PubMed Central

    Garcia-Gathright, Jean I.; Oh, Andrea; Abarca, Phillip A.; Han, Mary; Sago, William; Spiegel, Marshall L.; Wolf, Brian; Garon, Edward B.; Bui, Alex A.T.; Aberle, Denise R.

    2015-01-01

    This paper describes the information retrieval step in Casama (Contextualized Semantic Maps), a project that summarizes and contextualizes current research articles on driver mutations in non-small cell lung cancer. Casama’s representation of lung cancer studies aims to capture elements that will assist an end-user in retrieving studies and, importantly, judging their strength. This paper focuses on two types of study metadata: study objective and study design. 430 abstracts on EGFR and ALK mutations in lung cancer were annotated manually. Casama’s support vector machine (SVM) automatically classified the abstracts by study objective with as much as 129% higher F-scores compared to PubMed’s built-in filters. A second SVM classified the abstracts by epidemiological study design, suggesting strength of evidence at a more granular level than in previous work. The classification results and the top features determined by the classifiers suggest that this scheme would be generalizable to other mutations in lung cancer, as well as studies on driver mutations in other cancer domains. PMID:25618216

  11. Representing and extracting lung cancer study metadata: study objective and study design.

    PubMed

    Garcia-Gathright, Jean I; Oh, Andrea; Abarca, Phillip A; Han, Mary; Sago, William; Spiegel, Marshall L; Wolf, Brian; Garon, Edward B; Bui, Alex A T; Aberle, Denise R

    2015-03-01

    This paper describes the information retrieval step in Casama (Contextualized Semantic Maps), a project that summarizes and contextualizes current research papers on driver mutations in non-small cell lung cancer. Casama׳s representation of lung cancer studies aims to capture elements that will assist an end-user in retrieving studies and, importantly, judging their strength. This paper focuses on two types of study metadata: study objective and study design. 430 abstracts on EGFR and ALK mutations in lung cancer were annotated manually. Casama׳s support vector machine (SVM) automatically classified the abstracts by study objective with as much as 129% higher F-scores compared to PubMed׳s built-in filters. A second SVM classified the abstracts by epidemiological study design, suggesting strength of evidence at a more granular level than in previous work. The classification results and the top features determined by the classifiers suggest that this scheme would be generalizable to other mutations in lung cancer, as well as studies on driver mutations in other cancer domains. PMID:25618216

  12. Experimental studies on the effects of a sting support on the pressure distribution around a spherical object

    NASA Technical Reports Server (NTRS)

    Barna, P. S.

    1979-01-01

    Experiments were conducted on a spherical object, 2.5 inches in diameter, to obtain the pressure distribution around its meridan plane. In most of the tests the sphere was provided with a tail consisting of a circular cylinder that was attached directly to the rear with its axis in alignment with the center of the sphere. In some tests the tail was removed and the sphere alone was tested for comparison purposes. The main object of the tests was to obtain information on tail interference with the pressure distribution. The results of the tests show that the pressure distribution was affected by the presence of the tail to a minor extent only, while major differences occurred with the variation of the Reynolds number. The experiments were performed both in an open as well as inside a closed wind tunnel under steady flow conditions at Reynolds numbers ranging from 0.91 to 2.6 x 100000.

  13. Operationalizing the RE-AIM framework to evaluate the impact of multi-sector partnerships

    PubMed Central

    2014-01-01

    Background The RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework is a reliable tool for the translation of research to practice. This framework has been widely applied to assess the impact of individual interventions. However, RE-AIM has rarely been used to evaluate implementation interventions, especially from multi-sector partnerships. The primary purpose of this paper is to operationalize the RE-AIM approach to evaluate large, multi-sector partnerships. SCI Action Canada, a community-university partnership aimed to promote physical activity among adults with spinal cord injury, is used as an example. A secondary purpose is to provide initial data from SCI Action Canada by using this conceptualization of RE-AIM. Methods Each RE-AIM element is operationalized for multi-sector partnerships. Specific to SCI Action Canada, seven reach calculations, four adoption rates, four effectiveness outcomes, one implementation, one organizational maintenance, and two individual maintenance outcomes are defined. The specific numerators based on SCI Action Canada activities are also listed for each of these calculations. Results The results are derived from SCI Action Canada activities. SCI Action Canada’s reach ranged from 3% (end-user direct national reach) to 37% (total regional reach). Adoption rates were 15% (provincial level adoption) to 76% (regional level adoption). Implementation and organizational maintenance rates were 92% and 100%, respectively. Conclusions We have operationalized the RE-AIM framework for larger multi-sectoral partnerships and demonstrated its applicability to such partnerships with SCI Action Canada. Future partnerships could use RE-AIM to assess their public health impact. PMID:24923331

  14. A feasibility study on the implementation of satellite-to-satellite tracking around a small near-Earth object

    NASA Astrophysics Data System (ADS)

    Church, Christopher J.

    Near-earth objects (NEOs) are asteroids and comets that have a perihelion distance of less than 1.3 astronomical units (AU). There are currently more than 10,000 known NEOs. The majority of these objects are less than 1 km in diameter. Despite the number of NEOs, little is known about most of them. Characterizing these objects is a crucial component in developing a thorough understanding of solar system evolution, human exploration, exploitation of asteroid resources, and threat mitigation. Of particular interest is characterizing the internal structure of NEOs. While ground-based methods exist for characterizing the internal structure of NEOs, the information that can be gleaned from such studies is limited and often accompanied by large uncertainty. An alternative is to use in situ studies to examine an NEO's shape and gravity field, which can be used to assess its internal structure. This thesis investigates the use of satellite-to-satellite tracking (SST) to map the gravity field of a small NEO on the order of 500 m or less. An analysis of the mission requirements of two previously flown SST missions, GRACE and GRAIL, is conducted. Additionally, a simulation is developed to investigate the dynamics of SST in the vicinity of a small NEO. This simulation is then used to simulate range and range-rate data in the strongly perturbed environment of the small NEO. These data are used in conjunction with the analysis of the GRACE and GRAIL missions to establish a range of orbital parameters that can be used to execute a SST mission around a small NEO. Preliminary mission requirements for data collection and orbital correction maneuvers are also established. Additionally, the data are used to determine whether or not proven technology can be used to resolve the expected range and range-rate measurements. It is determined that the orbit semi-major axis for each spacecraft should be approximately 100% to 200% of the NEO's mean diameter and the two spacecraft should be in

  15. Philosophy and Objectives: Course of Study.

    ERIC Educational Resources Information Center

    Yeshiva of Flatbush, Brooklyn, NY. Joel Braverman High School.

    The Yeshiva of Flatbush, a high school located in the Midwood-Flatbush section of Brooklyn, New York, teaches both secular and Judaic studies with an emphasis upon transmitting the values and traditions of Halachic Judaism. The philosophy of the school is to provide an education in which Jewish studies are taught in Hebrew and to encourage student…

  16. Centering Objects in the Workspace

    ERIC Educational Resources Information Center

    Free, Cory

    2005-01-01

    Drafters must be detail-oriented people. The objects they draw are interpreted and then built with the extreme precision required by today's manufacturers. Now that computer-aided drafting (CAD) has taken over the drafting profession, anything less than exact precision is unacceptable. In her drafting classes, the author expects her students to…

  17. Planning and the "Measurable Objective."

    ERIC Educational Resources Information Center

    Miller, Ronald H.

    1973-01-01

    Accountability is being required of all America's institutions of higher education. Gallaudet College, an institution for the deaf in Washington, D.C., feels it has found a solution to the accountability problem in the use of "measurable objectives" in its program planning. The first phase from January 1 through June 30, 1972 of Gallaudet's…

  18. Self-reported and Objectively Measured Physical Activity Among a Cohort of Postpartum Women: The PIN Postpartum Study

    PubMed Central

    Evenson, Kelly R.; Herring, Amy H.; Wen, Fang

    2010-01-01

    Background Few studies measure physical activity objectively or at multiple time points during postpartum. We describe physical activity at 3- and 12-months postpartum among a cohort of women using both self-reported and objective measures. Methods In total, 181 women completed the 3-month postpartum measures, and 204 women completed the 12-month postpartum measures. Participants wore an Actigraph accelerometer for one week and completed in-home interviews that included questions on physical activity. A cohort of 80 women participated at both time points. Poisson regression models were used to determine whether physical activity differed over time for the cohort. Results For the cohort, average counts/minute were 364 at 3-months postpartum and 394 at 12-months postpartum. At both time periods for the cohort, vigorous activity averaged 1 to 3 minutes/day, and moderate activity (NHANES cutpoints) averaged 16 minutes/day. Sedentary time averaged 9.3 hours at 3-months postpartum and 8.8 hours at 12-months postpartum, out of a 19-hour day. Average counts/minute increased and sedentary behavior declined from 3- to 12-months postpartum. Conclusion Interventions are needed to help women integrate more moderate to vigorous physical activity and to capitalize on the improvements in sedentary behavior that occur during postpartum. PMID:22232505

  19. Mask CD control (CDC) using AIMS as the CD metrology data source

    NASA Astrophysics Data System (ADS)

    Ben-Zvi, Guy; Zait, Eitan; Dmitriev, Vladimir; Labovitz, Steven; Graitzer, Erez; Böhm, Klaus; Birkner, Robert; Scheruebl, Thomas

    2008-05-01

    It has been previously demonstrated that wafer CD uniformity can be improved via an ultrafast laser system. The system provides local CD Control (CDC) by writing inside the bulk of photomasks. Intra-field CD variation correction has been implemented effectively in mask-shops and fabs based on CD-SEM and Scatterometry (Optical CD or OCD) as the CD data source. Using wafer CD data allows correction of all wafer field CD contributors at once, but does not allow correcting for mask CD signature alone. For mask shops attempting to improve CDU of the mask regardless of the exposure tool, it is a better practice to use only mask CD data as the CD data source. In this study, we investigate the use of an aerial imaging system AIMSTM45-193i (AIMS45) as the mask CD data source for the CDC process. In order to determine the predictive value of the AIMS45 as input to the CDC process, we have created a programmed CD mask with both 45nm and 65nm node L/S and hole patterns. The programmed CD mask has CD errors of up to 20nm in 2.5nm steps (4X). The programmed CD mask was measured by AIMS45, defining the CDU map of the programmed CD mask. The CDU data was then used by Pixer CDC200TM to correct the CDU and bring it back to a flat, almost ideal CDU. In order to confirm that real CDU improvement on wafer had been achieved, the mask was printed before and after CDC on an immersion scanner at IMEC and results of pre and post CD data were compared.

  20. Aiming to complete the matrix: Eye-movement analysis of processing strategies in children's relational thinking.

    PubMed

    Chen, Zhe; Honomichl, Ryan; Kennedy, Diane; Tan, Enda

    2016-06-01

    The present study examines 5- to 8-year-old children's relation reasoning in solving matrix completion tasks. This study incorporates a componential analysis, an eye-tracking method, and a microgenetic approach, which together allow an investigation of the cognitive processing strategies involved in the development and learning of children's relational thinking. Developmental differences in problem-solving performance were largely due to deficiencies in engaging the processing strategies that are hypothesized to facilitate problem-solving performance. Feedback designed to highlight the relations between objects within the matrix improved 5- and 6-year-olds' problem-solving performance, as well as their use of appropriate processing strategies. Furthermore, children who engaged the processing strategies early on in the task were more likely to solve subsequent problems in later phases. These findings suggest that encoding relations, integrating rules, completing the model, and generalizing strategies across tasks are critical processing components that underlie relational thinking. (PsycINFO Database Record PMID:27148778

  1. Heteropolyhedral silver compounds containing the polydentate ligand N,N,O-E-[6-(hydroxyimino)ethyl]-1,3,7-trimethyllumazine. Preparation, spectral and XRD structural study and AIM calculations.

    PubMed

    Jiménez-Pulido, Sonia B; Hueso-Ureña, Francisco; Fernández-Liencres, M Paz; Fernández-Gómez, Manuel; Moreno-Carretero, Miguel N

    2013-01-14

    The oxime derived from 6-acetyl-1,3,7-trimethyllumazine (1) ((E-6-(hydroxyimino)ethyl)-1,3,7-trimethylpteridine-2,4(1H,3H)-dione, DLMAceMox) has been prepared and its molecular and crystal structure determined from spectral and XRD data. The oxime ligand was reacted with silver nitrate, perchlorate, thiocyanate, trifluoromethylsulfonate and tetrafluoroborate to give complexes with formulas [Ag(2)(DLMAceMox)(2)(NO(3))(2)](n) (2), [Ag(2)(DLMAceMox)(2)(ClO(4))(2)](n) (3), [Ag(2)(DLMAceMox)(2)(SCN)(2)] (4), [Ag(2)(DLMAceMox)(2)(CF(3)SO(3))(2)(CH(3)CH(2)OH)]·CH(3)CH(2)OH (5) and [Ag(DLMAceMox)(2)]BF(4) (6). Single-crystal XRD studies show that the asymmetrical residual unit of complexes 2, 3 and 5 contains two quite different but connected silver centers (Ag1-Ag2, 2.9-3.2 Å). In addition to this, the Ag1 ion displays coordination with the N5 and O4 atoms from both lumazine moieties and a ligand (nitrato, perchlorato or ethanol) bridging to another disilver unit. The Ag2 ion is coordinated to the N61 oxime nitrogens, a monodentate and a (O,O)-bridging nitrato/perchlorato or two monodentate O-trifluoromethylsulfonato anions. The coordination polyhedra can be best described as a strongly distorted octahedron (around Ag1) and a square-based pyramid (around Ag2). The Ag-N and Ag-O bond lengths range between 2.22-2.41 and 2.40-2.67 Å, respectively. Although the structure of 4 cannot be resolved by XRD, it is likely to be similar to those described for 2, 3 and 5, containing Ag-Ag units with S-thiocyanato terminal ligands. Finally, the structure of the tetrafluoroborate compound 6 is mononuclear with a strongly distorted tetrahedral AgN(4) core (Ag-N, 2.27-2.43 Å). Always, the different Ag-N distances found clearly point to the more basic character of the oxime N61 nitrogen atom when compared with the pyrazine N5 one. A topological analysis of the electron density within the framework provided by the quantum theory of atoms in molecules (QTAIM) using DFT(M06L) levels of

  2. A role for the apoptosis inhibitory factor AIM/Spalpha/Api6 in atherosclerosis development.

    PubMed

    Arai, Satoko; Shelton, John M; Chen, Mingyi; Bradley, Michelle N; Castrillo, Antonio; Bookout, Angie L; Mak, Puiying A; Edwards, Peter A; Mangelsdorf, David J; Tontonoz, Peter; Miyazaki, Toru

    2005-03-01

    Macrophages play a central role in the development of atherosclerosis through the accumulation of oxidized LDL (oxLDL). AIM (Spalpha/Api6) has previously been shown to promote macrophage survival; however, its function in atherogenesis is unknown. Here we identify AIM as a critical factor that protects macrophages from the apoptotic effects of oxidized lipids. AIM protein is induced in response to oxLDL loading and is highly expressed in foam cells within atherosclerotic lesions. Interestingly, both expression of AIM in lesions and its induction by oxidized lipids require the action of LXR/RXR heterodimers. AIM-/- macrophages are highly susceptible to oxLDL-induced apoptosis in vitro and undergo accelerated apoptosis in atherosclerotic lesions in vivo. Moreover, early atherosclerotic lesions in AIM-/-LDLR-/- double knockout mice are dramatically reduced when compared to AIM+/+LDLR-/- controls. We conclude that AIM production facilitates macrophage survival within atherosclerotic lesions and that loss of AIM decreases early lesion development by increasing macrophage apoptosis. PMID:16054063

  3. [Global Adult Tobacco Survey in Poland--the aim and current experiences].

    PubMed

    Kaleta, Dorota; Kozieł, Anna; Miśkiewicz, Paulina

    2009-01-01

    Poland is one of the countries, where smoking is widely spread and smoking-induced diseases have become a significant health and socio-economic issue. Since 1999, the World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC), in cooperation with partner organizations have been working on the implementation of the global control system known as the Global Tobacco Surveillance System (GTSS). This system expands the opportunities of individual countries in the area of designing, implementing and evaluating comprehensive anti-tobacco programs. The Global Adult Tobacco Survey (GATS) has been incorporated into the GTSS system in 2007. The aim of the work is to explain and promote the objectives of GATS and the process of its implementation in Poland based on current experiences of the WHO Country Office for Poland. GATS concentrates on monitoring of tobacco use by adults (aged over 15 years). It is a representative, national survey of households, standardized on a global scale. GATS is supported by Bloomberg Philanthropies as a part of the Bloomberg Global Initiative to Reduce Tobacco Use. Two executive agencies, the M. Skłodowska-Curie Institute of Oncology, Warsaw and the Warsaw Medical University, have been assigned to implement the Global Adult Tobacco Survey in Poland. The prepatory works for pre-testing and further stages of the survey implementation are currently under the final phase. Data gathered by GATS will enable us to learn more about the use of tobacco by the adult population in Poland. They will also indicate the most effective methods of the tobacco control in our country. PMID:19746887

  4. The Objective of Financial Reporting.

    ERIC Educational Resources Information Center

    Schermann, Kenneth R.

    1986-01-01

    Alerts public school business officials to a financial reporting concepts statement to be issued by the Governmental Accounting Standards Board in late 1986. The new directive will outline four objectives concerned with accountability procedures, resource management and compliance information, operating results, and future financial capabilities.…

  5. The Trouble with Learning Objects

    ERIC Educational Resources Information Center

    Parrish, Patrick E.

    2004-01-01

    Object-oriented instructional design (OOID) offers the promise of universal access to online instructional materials, increased productivity among trainers and educators, and solutions for individualizing learning. However, it is unclear whether it can fulfill these promises to the degree many envision. As with every new instructional technology,…

  6. Density functional theory study of the interaction of vinyl radical, ethyne, and ethene with benzene, aimed to define an affordable computational level to investigate stability trends in large van der Waals complexes

    SciTech Connect

    Maranzana, Andrea E-mail: anna.giordana@hotmail.com E-mail: mauro.causa@unina.it Giordana, Anna E-mail: anna.giordana@hotmail.com E-mail: mauro.causa@unina.it Indarto, Antonius Tonachini, Glauco; Barone, Vincenzo E-mail: anna.giordana@hotmail.com E-mail: mauro.causa@unina.it; Causà, Mauro E-mail: anna.giordana@hotmail.com E-mail: mauro.causa@unina.it; Pavone, Michele E-mail: anna.giordana@hotmail.com E-mail: mauro.causa@unina.it

    2013-12-28

    Our purpose is to identify a computational level sufficiently dependable and affordable to assess trends in the interaction of a variety of radical or closed shell unsaturated hydro-carbons A adsorbed on soot platelet models B. These systems, of environmental interest, would unavoidably have rather large sizes, thus prompting to explore in this paper the performances of relatively low-level computational methods and compare them with higher-level reference results. To this end, the interaction of three complexes between non-polar species, vinyl radical, ethyne, or ethene (A) with benzene (B) is studied, since these species, involved themselves in growth processes of polycyclic aromatic hydrocarbons (PAHs) and soot particles, are small enough to allow high-level reference calculations of the interaction energy ΔE{sub AB}. Counterpoise-corrected interaction energies ΔE{sub AB} are used at all stages. (1) Density Functional Theory (DFT) unconstrained optimizations of the A−B complexes are carried out, using the B3LYP-D, ωB97X-D, and M06-2X functionals, with six basis sets: 6-31G(d), 6-311 (2d,p), and 6-311++G(3df,3pd); aug-cc-pVDZ and aug-cc-pVTZ; N07T. (2) Then, unconstrained optimizations by Møller-Plesset second order Perturbation Theory (MP2), with each basis set, allow subsequent single point Coupled Cluster Singles Doubles and perturbative estimate of the Triples energy computations with the same basis sets [CCSD(T)//MP2]. (3) Based on an additivity assumption of (i) the estimated MP2 energy at the complete basis set limit [E{sub MP2/CBS}] and (ii) the higher-order correlation energy effects in passing from MP2 to CCSD(T) at the aug-cc-pVTZ basis set, ΔE{sub CC-MP}, a CCSD(T)/CBS estimate is obtained and taken as a computational energy reference. At DFT, variations in ΔE{sub AB} with basis set are not large for the title molecules, and the three functionals perform rather satisfactorily even with rather small basis sets [6-31G(d) and N07T], exhibiting

  7. Density functional theory study of the interaction of vinyl radical, ethyne, and ethene with benzene, aimed to define an affordable computational level to investigate stability trends in large van der Waals complexes

    NASA Astrophysics Data System (ADS)

    Maranzana, Andrea; Giordana, Anna; Indarto, Antonius; Tonachini, Glauco; Barone, Vincenzo; Causà, Mauro; Pavone, Michele

    2013-12-01

    Our purpose is to identify a computational level sufficiently dependable and affordable to assess trends in the interaction of a variety of radical or closed shell unsaturated hydro-carbons A adsorbed on soot platelet models B. These systems, of environmental interest, would unavoidably have rather large sizes, thus prompting to explore in this paper the performances of relatively low-level computational methods and compare them with higher-level reference results. To this end, the interaction of three complexes between non-polar species, vinyl radical, ethyne, or ethene (A) with benzene (B) is studied, since these species, involved themselves in growth processes of polycyclic aromatic hydrocarbons (PAHs) and soot particles, are small enough to allow high-level reference calculations of the interaction energy ΔEAB. Counterpoise-corrected interaction energies ΔEAB are used at all stages. (1) Density Functional Theory (DFT) unconstrained optimizations of the A-B complexes are carried out, using the B3LYP-D, ωB97X-D, and M06-2X functionals, with six basis sets: 6-31G(d), 6-311 (2d,p), and 6-311++G(3df,3pd); aug-cc-pVDZ and aug-cc-pVTZ; N07T. (2) Then, unconstrained optimizations by Møller-Plesset second order Perturbation Theory (MP2), with each basis set, allow subsequent single point Coupled Cluster Singles Doubles and perturbative estimate of the Triples energy computations with the same basis sets [CCSD(T)//MP2]. (3) Based on an additivity assumption of (i) the estimated MP2 energy at the complete basis set limit [EMP2/CBS] and (ii) the higher-order correlation energy effects in passing from MP2 to CCSD(T) at the aug-cc-pVTZ basis set, ΔECC-MP, a CCSD(T)/CBS estimate is obtained and taken as a computational energy reference. At DFT, variations in ΔEAB with basis set are not large for the title molecules, and the three functionals perform rather satisfactorily even with rather small basis sets [6-31G(d) and N07T], exhibiting deviation from the computational

  8. Density functional theory study of the interaction of vinyl radical, ethyne, and ethene with benzene, aimed to define an affordable computational level to investigate stability trends in large van der Waals complexes.

    PubMed

    Maranzana, Andrea; Giordana, Anna; Indarto, Antonius; Tonachini, Glauco; Barone, Vincenzo; Causà, Mauro; Pavone, Michele

    2013-12-28

    Our purpose is to identify a computational level sufficiently dependable and affordable to assess trends in the interaction of a variety of radical or closed shell unsaturated hydro-carbons A adsorbed on soot platelet models B. These systems, of environmental interest, would unavoidably have rather large sizes, thus prompting to explore in this paper the performances of relatively low-level computational methods and compare them with higher-level reference results. To this end, the interaction of three complexes between non-polar species, vinyl radical, ethyne, or ethene (A) with benzene (B) is studied, since these species, involved themselves in growth processes of polycyclic aromatic hydrocarbons (PAHs) and soot particles, are small enough to allow high-level reference calculations of the interaction energy ΔEAB. Counterpoise-corrected interaction energies ΔEAB are used at all stages. (1) Density Functional Theory (DFT) unconstrained optimizations of the A-B complexes are carried out, using the B3LYP-D, ωB97X-D, and M06-2X functionals, with six basis sets: 6-31G(d), 6-311 (2d,p), and 6-311++G(3df,3pd); aug-cc-pVDZ and aug-cc-pVTZ; N07T. (2) Then, unconstrained optimizations by Møller-Plesset second order Perturbation Theory (MP2), with each basis set, allow subsequent single point Coupled Cluster Singles Doubles and perturbative estimate of the Triples energy computations with the same basis sets [CCSD(T)//MP2]. (3) Based on an additivity assumption of (i) the estimated MP2 energy at the complete basis set limit [EMP2/CBS] and (ii) the higher-order correlation energy effects in passing from MP2 to CCSD(T) at the aug-cc-pVTZ basis set, ΔECC-MP, a CCSD(T)/CBS estimate is obtained and taken as a computational energy reference. At DFT, variations in ΔEAB with basis set are not large for the title molecules, and the three functionals perform rather satisfactorily even with rather small basis sets [6-31G(d) and N07T], exhibiting deviation from the computational

  9. An Aims-Based Curriculum Illustrated by the Teaching of Science in Schools

    ERIC Educational Resources Information Center

    Reiss, Michael J.; White, John

    2014-01-01

    We begin by arguing that curriculum development should start with aims rather than, as is typically the case, with subjects. We, therefore, ask what might be the fundamental aims of school education. We conclude that they are twofold, namely, to enable each learner to lead a life that is personally flourishing and to help others to do so too.…

  10. Precision disablement aiming system

    DOEpatents

    Monda, Mark J.; Hobart, Clinton G.; Gladwell, Thomas Scott

    2016-02-16

    A disrupter to a target may be precisely aimed by positioning a radiation source to direct radiation towards the target, and a detector is positioned to detect radiation that passes through the target. An aiming device is positioned between the radiation source and the target, wherein a mechanical feature of the aiming device is superimposed on the target in a captured radiographic image. The location of the aiming device in the radiographic image is used to aim a disrupter towards the target.

  11. The Moral and Ethical Aims of the School Viewed through a Cosmopolitan Prism

    ERIC Educational Resources Information Center

    Hansen, David T.

    2013-01-01

    In this chapter, the author proposes to imagine the aims of the school in light of a cosmopolitan philosophy of education. The first section that follows provides a summary account of what the author takes cosmopolitanism to mean. The second section frames a philosophy of education that stems from this account. The third and penultimate section…

  12. The StrongWomen-Healthy Hearts program in Pennsylvania: RE-AIM analysis.

    PubMed

    Folta, Sara C; Lichtenstein, Alice H; Seguin, Rebecca A; Goldberg, Jeanne P; Corbin, Marilyn A; Wiker, Nancy; Gauker, Jodi; Chui, Kenneth; Nelson, Miriam E

    2015-03-01

    Dissemination of evidence-based programs is needed to reduce CVD risk among midlife and older women. The aim of this study is to examine the public health impact of StrongWomen-Healthy Hearts in Pennsylvania using the RE-AIM framework. Reach, adoption, implementation, and maintenance were assessed using qualitative and quantitative measures; effectiveness was assessed using a pretest-posttest within-participants design. Reach into the target population was 5 in 100,000. Compared to the target population, a greater percentage of participants were white, married, middle-class, and had a graduate degree. Effectiveness was demonstrated (weight loss -2.0 kg, p < 0.001). Adoption among trained leaders was high (83.3 %), as was fidelity in implementation (average score 9.3 of 10). No leaders maintained the program. To increase impact of the StrongWomen-Healthy Hearts Program, it will be important to lower the costs and modify the recruitment and training strategies to better reach low-income and minority women. Such strategies may also improve program maintenance. PMID:25729458

  13. Landslide mapping with multi-scale object-based image analysis - a case study in the Baichi watershed, Taiwan

    NASA Astrophysics Data System (ADS)

    Lahousse, T.; Chang, K. T.; Lin, Y. H.

    2011-10-01

    We developed a multi-scale OBIA (object-based image analysis) landslide detection technique to map shallow landslides in the Baichi watershed, Taiwan, after the 2004 Typhoon Aere event. Our semi-automated detection method selected multiple scales through landslide size statistics analysis for successive classification rounds. The detection performance achieved a modified success rate (MSR) of 86.5% with the training dataset and 86% with the validation dataset. This performance level was due to the multi-scale aspect of our methodology, as the MSR for single scale classification was substantially lower, even after spectral difference segmentation, with a maximum of 74%. Our multi-scale technique was capable of detecting landslides of varying sizes, including very small landslides, up to 95 m2. The method presented certain limitations: the thresholds we established for classification were specific to the study area, to the landslide type in the study area, and to the spectral characteristics of the satellite image. Because updating site-specific and image-specific classification thresholds is easy with OBIA software, our multi-scale technique is expected to be useful for mapping shallow landslides at watershed level.

  14. Perceptions of postgraduate trainees on the impact of objective structured clinical examinations on their study behavior and clinical practice

    PubMed Central

    Opoka, Robert O; Kiguli, Sarah; Ssemata, Andrew S; Govaerts, Marjan; Driessen, Erik W

    2015-01-01

    Background The objective structured clinical examination (OSCE) is a commonly used method of assessing clinical competence at various levels, including at the postgraduate level. How the OSCE impacts on learning in higher education is poorly described. In this study, we evaluated the perceptions of postgraduate trainees regarding the impact of the OSCE on their study and clinical behavior. Methods We employed an explorative qualitative research design by conducting focus group discussions with 41 pediatric postgraduate trainees at the College of Health Science, Makerere University. A semi-structured tool was used to obtain the views and experiences of the trainees. Transcripts from the discussion were analyzed in an iterative manner using thematic content analysis. Results The trainees reported the OSCEs as a fair and appropriate tool for assessing clinical competency at the postgraduate level. However, they noted that whereas OSCEs assess a broad range of skills and competencies relevant to their training, there were areas that they did not adequately assess. In particular, OSCEs did not adequately assess in-depth clinical knowledge or detailed history-taking skills. Overall, the majority of the trainees reported that the OSCEs inspired them to study widely and improve their procedural and communication skills. Conclusion OSCEs are a useful tool for assessing clinical competencies in postgraduate education. However, the perceived limitations in their ability to assess complex skills raises concerns about their use as a standalone mode of assessment at the postgraduate level. Future studies should evaluate how use of OSCEs in combination with other assessment tools impacts on learning. PMID:26082673

  15. A Study of the Development of Students' Visualizations of Program State during an Elementary Object-Oriented Programming Course

    ERIC Educational Resources Information Center

    Sajaniemi, Jorma; Kuittinen, Marja; Tikansalo, Taina

    2008-01-01

    Students' understanding of object-oriented (OO) program execution was studied by asking students to draw a picture of a program state at a specific moment. Students were given minimal instructions on what to include in their drawings in order to see what they considered to be central concepts and relationships in program execution. Three drawing…

  16. The developmental pattern of stimulus and response interference in a color-object Stroop task: an ERP study

    PubMed Central

    Jongen, Ellen MM; Jonkman, Lisa M

    2008-01-01

    Background Several studies have shown that Stroop interference is stronger in children than in adults. However, in a standard Stroop paradigm, stimulus interference and response interference are confounded. The purpose of the present study was to determine whether interference at the stimulus level and the response level are subject to distinct maturational patterns across childhood. Three groups of children (6–7 year-olds, 8–9 year-olds, and 10–12 year-olds) and a group of adults performed a manual Color-Object Stroop designed to disentangle stimulus interference and response interference. This was accomplished by comparing three trial types. In congruent (C) trials there was no interference. In stimulus incongruent (SI) trials there was only stimulus interference. In response incongruent (RI) trials there was stimulus interference and response interference. Stimulus interference and response interference were measured by a comparison of SI with C, and RI with SI trials, respectively. Event-related potentials (ERPs) were measured to study the temporal dynamics of these processes of interference. Results There was no behavioral evidence for stimulus interference in any of the groups, but in 6–7 year-old children ERPs in the SI condition in comparison with the C condition showed an occipital P1-reduction (80–140 ms) and a widely distributed amplitude enhancement of a negative component followed by an amplitude reduction of a positive component (400–560 ms). For response interference, all groups showed a comparable reaction time (RT) delay, but children made more errors than adults. ERPs in the RI condition in comparison with the SI condition showed an amplitude reduction of a positive component over lateral parietal (-occipital) sites in 10–12 year-olds and adults (300–540 ms), and a widely distributed amplitude enhancement of a positive component in all age groups (680–960 ms). The size of the enhancement correlated positively with the RT response

  17. Learning Objects in Practice: The Integration of Reusable Learning Objects in Primary Education

    ERIC Educational Resources Information Center

    Cameron, Tiffani; Bennett, Sue

    2010-01-01

    The study described in this paper investigated the use of "The Le@rning Federation's" learning objects by students in primary school education. The study focused on how students engaged with and responded to the learning objects and how the objects supported student learning. A collective case study design allowed the researchers to investigate…

  18. The display of molecular models with the Ames Interactive Modeling System (AIMS)

    NASA Technical Reports Server (NTRS)

    Egan, J. T.; Hart, J.; Burt, S. K.; Macelroy, R. D.

    1982-01-01

    A visualization of molecular models can lead to a clearer understanding of the models. Sophisticated graphics devices supported by minicomputers make it possible for the chemist to interact with the display of a very large model, altering its structure. In addition to user interaction, the need arises also for other ways of displaying information. These include the production of viewgraphs, film presentation, as well as publication quality prints of various models. To satisfy these needs, the display capability of the Ames Interactive Modeling System (AIMS) has been enhanced to provide a wide range of graphics and plotting capabilities. Attention is given to an overview of the AIMS system, graphics hardware used by the AIMS display subsystem, a comparison of graphics hardware, the representation of molecular models, graphics software used by the AIMS display subsystem, the display of a model obtained from data stored in molecule data base, a graphics feature for obtaining single frame permanent copy displays, and a feature for producing multiple frame displays.

  19. Tracking moving objects with megavoltage portal imaging: A feasibility study

    SciTech Connect

    Meyer, Juergen; Richter, Anne; Baier, Kurt; Wilbert, Juergen; Guckenberger, Matthias; Flentje, Michael

    2006-05-15

    Four different algorithms were investigated with the aim to determine their suitability to track an object in conventional megavoltage portal images. The algorithms considered were the mean of the sum of squared differences (MSSD), mutual information (MI), the correlation ratio (CR), and the correlation coefficient (CC). Simulation studies were carried out with various image series containing a rigid object of interest that was moved along a predefined trajectory. For each of the series the signal-to-noise ratio (SNR) was varied to compare the performance of the algorithms under noisy conditions. For a poor SNR of -6 dB the mean tracking error was 2.4, 6.5, 39.0, and 17.2 pixels for MSSD, CC, CR and MI, respectively, with a standard deviation of 1.9, 12.9, 19.5, and 7.5 pixels, respectively. The size of a pixel was 0.5 mm. These results improved to 1.1, 1.3, 1.3, and 2.0 pixels, respectively, with a standard deviation of 0.6, 0.8, 0.8, and 2.1 pixels, respectively, when a mean filter was applied to the images prior to tracking. The implementation of MSSD into existing in-house software demonstrated that, depending on the search range, it was possible to process between 2 and 15 images/s, making this approach capable of real-time applications. In conclusion, the best geometric tracking accuracy overall was obtained with MSSD, followed by CC, CR, and MI. The simplest and best algorithm, both in terms of geometric accuracy as well as computational cost, was the MSSD algorithm and was therefore the method of choice.

  20. [Aiming for the adolescent market: internet and video games, the new strategies of the tobacco industry].

    PubMed

    Barrientos-Gutiérrez, Tonatiuh; Barrientos-Gutiérrez, Inti; Reynales-Shigematsu, Luz Myriam; Thrasher, James F; Lazcano-Ponce, Eduardo

    2012-06-01

    Exposure to tobacco advertisement is associated with smoking initiation among the youth, its elimination is a key objective to effectively curb the tobacco epidemic. Historically, the tobacco industry has pioneered the use of new communication technologies to keep and expand their market. Nowadays, Internet and video games have transcended the entertainment sphere, becoming significant media for massive communication and providing new opportunities for advertisement. The present essay reviews the existing literature on tobacco presence in the Internet and video games to define research and policy tasks required to develop effective means for tobacco advertisement regulation and control. PMID:22689169

  1. Increasing the number of feminist scientists: why feminist aims are not served by the Underdetermination Thesis

    NASA Astrophysics Data System (ADS)

    Intemann, Kristen

    2008-11-01

    Recent feminist philosophers of science have argued that feminist values can contribute to rational decisions about which scientific theories to accept. On this view, increasing the number of feminist scientists is important for ensuring rational and objective theory acceptance. The Underdetermination Thesis has played a key role in arguments for this view [Anderson (1995) Hypatia 10(3), 50 84; Hankinson Nelson (1990) Who knows? From Quine to a feminist empiricism. Temple University Press, Philadelphia; Longino (1990) Science as social knowledge. Princeton University Press, Princeton; Longino (2002) The fate of knowledge. Princeton University Press, Princeton; Kourany (2003) Philosophy of Science 70, 1 14]. This thesis is alleged to open an argumentative “gap” between evidence and theory acceptance and provide a rationale for filling the gap with feminist values. While I agree with the conclusion that feminist values can contribute to rational decisions about which theories to accept, I argue that the Underdetermination Thesis cannot support this claim. First, using earlier arguments [Laudan (1990) in: R. Giere (ed) Minnesota studies in the philosophy of science, vol 14, pp 267 297; Slezak (1991) International Studies in Philosophy of Science 5, 241 256; Pinnick (1994) Philosophy of Science 61, 664 657] I show that Underdetermination cannot, by itself, establish that feminist values should fill the gap in theory acceptance. Secondly, I argue that the very use of the Underdetermination Thesis concedes that feminist values are extra-scientific, a-rational, factors in theory acceptance. This concession denies feminists grounds to explain why their values contribute to rational scientific reasoning. Finally, I propose two alternative ways to explain how feminist values can contribute to rational theory acceptance that do not rely on Underdetermination.

  2. The relation of object naming and other visual speech production tasks:A large scale voxel-based morphometric study

    PubMed Central

    Lau, Johnny King L.; Humphreys, Glyn W.; Douis, Hassan; Balani, Alex; Bickerton, Wai-ling; Rotshtein, Pia

    2015-01-01

    We report a lesion–symptom mapping analysis of visual speech production deficits in a large group (280) of stroke patients at the sub-acute stage (<120 days post-stroke). Performance on object naming was evaluated alongside three other tests of visual speech production, namely sentence production to a picture, sentence reading and nonword reading. A principal component analysis was performed on all these tests' scores and revealed a ‘shared’ component that loaded across all the visual speech production tasks and a ‘unique’ component that isolated object naming from the other three tasks. Regions for the shared component were observed in the left fronto-temporal cortices, fusiform gyrus and bilateral visual cortices. Lesions in these regions linked to both poor object naming and impairment in general visual–speech production. On the other hand, the unique naming component was potentially associated with the bilateral anterior temporal poles, hippocampus and cerebellar areas. This is in line with the models proposing that object naming relies on a left-lateralised language dominant system that interacts with a bilateral anterior temporal network. Neuropsychological deficits in object naming can reflect both the increased demands specific to the task and the more general difficulties in language processing. PMID:25685713

  3. Aims and Results of the 23rd International Conference on Vacuum Technique and Technology (VTT2016)

    NASA Astrophysics Data System (ADS)

    Lisenkov, A. A.; Kostrin, D. K.; Pavlova, V. A.

    2016-07-01

    In this preface the main features, aims and results of the 23rd International Conference on Vacuum Technique and Technology (VTT2016) that was held on 7-9 June 2016 in Saint Petersburg, Russia are discussed.

  4. The perception of concurrent sound objects through the use of harmonic enhancement: a study of auditory attention.

    PubMed

    Koulaguina, Elena; Drisdelle, Brandi Lee; Alain, Claude; Grimault, Stephan; Eck, Douglas; Vachon, François; Jolicoeur, Pierre

    2015-04-01

    When the frequency of one harmonic, in a sound composed of many harmonics, is briefly mistuned and then returned to the 'in-tune' frequency and phase, observers report hearing this harmonic as a separate tone long after the brief period of mistuning - a phenomenon called harmonic enhancement. Here, we examined the consequence of harmonic enhancement on listeners' ability to detect a brief amplitude notch embedded in one of the harmonics after the period of mistuning. When present, the notch was either on the enhanced harmonic or on a different harmonic. Detection was better on the enhanced harmonic than on a non-enhanced harmonic. This finding suggests that attention was drawn to the enhanced harmonic (which constituted a new sound object) thereby easing the processing of sound features (i.e., a notch) within that object. This is the first evidence of a functional consequence of the after-effect of transient mistuning on auditory perception. Moreover, the findings provide support for an attention-based explanation of the enhancement phenomenon. PMID:25678273

  5. The subjective experience of object recognition: comparing metacognition for object detection and object categorization.

    PubMed

    Meuwese, Julia D I; van Loon, Anouk M; Lamme, Victor A F; Fahrenfort, Johannes J

    2014-05-01

    Perceptual decisions seem to be made automatically and almost instantly. Constructing a unitary subjective conscious experience takes more time. For example, when trying to avoid a collision with a car on a foggy road you brake or steer away in a reflex, before realizing you were in a near accident. This subjective aspect of object recognition has been given little attention. We used metacognition (assessed with confidence ratings) to measure subjective experience during object detection and object categorization for degraded and masked objects, while objective performance was matched. Metacognition was equal for degraded and masked objects, but categorization led to higher metacognition than did detection. This effect turned out to be driven by a difference in metacognition for correct rejection trials, which seemed to be caused by an asymmetry of the distractor stimulus: It does not contain object-related information in the detection task, whereas it does contain such information in the categorization task. Strikingly, this asymmetry selectively impacted metacognitive ability when objective performance was matched. This finding reveals a fundamental difference in how humans reflect versus act on information: When matching the amount of information required to perform two tasks at some objective level of accuracy (acting), metacognitive ability (reflecting) is still better in tasks that rely on positive evidence (categorization) than in tasks that rely more strongly on an absence of evidence (detection). PMID:24554231

  6. Increasing the Number of Feminist Scientists: Why Feminist Aims Are Not Served by the Underdetermination Thesis

    ERIC Educational Resources Information Center

    Intemann, Kristen

    2008-01-01

    Recent feminist philosophers of science have argued that feminist values can contribute to rational decisions about which scientific theories to accept. On this view, increasing the number of feminist scientists is important for ensuring rational and objective theory acceptance. The Underdetermination Thesis has played a key role in arguments for…

  7. São Paulo Megacity Mental Health Survey - a population-based epidemiological study of psychiatric morbidity in the São Paulo metropolitan area: aims, design and field implementation.

    PubMed

    Viana, Maria Carmen; Teixeira, Marlene Galativicis; Beraldi, Fidel; Bassani, Indaiá de Santana; Andrade, Laura Helena

    2009-12-01

    The São Paulo Megacity Mental Health Survey is a population-based cross-sectional survey of psychiatric morbidity, assessing a probabilistic sample of household residents in the São Paulo Metropolitan Area, aged 18 years and over. Respondents were selected from a stratified multistage clustered area probability sample of households, covering all 39 municipalities, without replacement. Respondents were assessed using the World Mental Health Survey version of the World Health Organization Composite International Diagnostic Interview (WMH-CIDI), which was translated and adapted into the Brazilian-Portuguese language. Data was collected between May 2005 and April 2007 by trained lay interviewers. The World Mental Health Survey version of the Composite International Diagnostic Interview comprises clinical and non-clinical sections, arranged as Part I and Part II, producing diagnoses according to the Diagnostic and Statistical Manual of Mental Disorders - Fourth Edition, and the International Classification of Diseases - 10th Revision. Mood, anxiety, impulse-control and substance use disorders, and suicide-related behavior, considered core disorders, as well as socio-demographic information, were assessed in all respondents. Non-clinical modules and non-core clinical sections (obsessive-compulsive disorder, post-traumatic stress disorder, gambling, eating disorders, neurasthenia, pre-menstrual disorders, psychotic symptoms and personality traits) were assessed in a sub-sample (2,942 respondents), composed by all respondents with at least one core disorder and a 25% random sample of those who were non-cases. A total of 5,037 individuals were interviewed, with a global response rate of 81.3%. Saliva samples were collected from 1,801 respondents, with DNA extracted stored pending further investigations. PMID:20098829

  8. Concept study of a multi-object AO system for the EAGLE instrument on the European ELT

    NASA Astrophysics Data System (ADS)

    Fusco, T.; Rousset, G.; Assémat, F.; Neichel, B.; Gendron, E.; Myers, R. M.; Morris, T.; Chemla, F.; Robert, C.; Bryson, I.; Cuby, J. G.

    2008-07-01

    EAGLE is a wide FoV (5 arcmin diameter), multi-objects (at least 20) integral-field spectrograph (R>4000) for the E-ELT. The top level requirements are to concentrate 30 to 40 % of the photons collected by the E-ELT in a focal area of 75x75 mas2 in H band. This leads to the selection of the Multi Object Adaptive Optics in order to deliver such a performance in a so-large FoV. In this paper, we present a detailed analysis of the error budget for an MOAO system in EAGLE. It is based on numerical simulation results. The budget is splitted in LGS and NGS contributions. The analysis leads to share the specifications between low spatial frequencies and high spatial frequencies in the wave-front errors. Finally a preliminary conceptual design of the MOAO system is deduced including 9 LGS for tomography and a 9000 actuator deformable mirror per channel.

  9. On the Relations between Action Planning, Object Identification, and Motor Representations of Observed Actions and Objects

    ERIC Educational Resources Information Center

    Vainio, Lari; Symes, Ed; Ellis, Rob; Tucker, Mike; Ottoboni, Giovanni

    2008-01-01

    Recent evidence suggests that viewing a static prime object (a hand grasp), can activate action representations that affect the subsequent identification of graspable target objects. The present study explored whether stronger effects on target object identification would occur when the prime object (a hand grasp) was made more action-rich and…

  10. The Role of Object Recognition in Young Infants' Object Segregation.

    ERIC Educational Resources Information Center

    Carey, Susan; Williams, Travis

    2001-01-01

    Discusses Needham's findings by asserting that they extend understanding of infant perception by showing that the memory representations infants draw upon have bound together information about shape, color, and pattern. Considers the distinction between two senses of "recognition" and asks in which sense object recognition contributes to object…

  11. The Origin of Apollo Objects

    SciTech Connect

    Perlmutter, Saul

    1984-03-29

    The source of the Earth-orbit-crossing asteroids has been much debated. (This class of asteroidal bodies includes the Apollo, Aten, and some Amor objects, each with its own orbital characteristics; we shall use the term Apollo objects to mean all Earth-crossers.) It is difficult to find a mechanism which would create new Apollo objects at a sufficient rate to balance the loss due to collision with planets and ejection from the solar system, and thus explain the estimated steady-state number. A likely source is the main asteroid belt, since it has similar photometric characteristics. There are gaps in the main belt which correspond to orbits resonant with the orbits of Jupiter and Saturn, and it has been shown that the resonances can perturb a body into an Earth-crossing orbit. Apollo objects could thus be generated when random collisions between asteroids in the main belt sent fragments into these resonant orbits. Calculations of the creation rate from these random collisions, however, yielcl numbers too low by a factor of four. This rate could be significantly lower given the uncertainty in the efficiency of the resonance mechanism. As an alternative, it was suggested that the evaporation of a comet's volatile mantle as it passes near the sun could provide enough non-gravitational force to move the comet into an orbit with aphelion inside of Jupiter's orbit, and thus safe from ejection from the solar system. The probability of such an event occurring is unknown, although the recent discovery of the 'asteroid' 1983 TB, with an orbit matching that of the Geminid meteor shower, suggests that such a mechanism has occurred at least once. New evidence from paleontology and geophysics, however, suggests a better solution to the problem of the source of the Apollos. M. Davis, P. Hut, and R. A. Muller recently proposed that an unseen companion to the sun passes through the Oort cloud every 28 million years, sending a shower of comets to the Earth; this provides an

  12. The object of environmental ethics

    NASA Astrophysics Data System (ADS)

    Petulla, Joseph M.

    1989-05-01

    Since the term “environmental ethics” began to be used a generation ago, it has covered many different kinds of environmental notions, problems, ethical systems, and forms of behavior. A variety of cases are presented and examined under two terms, environmental ethics and ecological morality, in an effort to illustrate different kinds of ethical objectives. In order to understand the connections between various strands of environmental ethics, personal and social values and subcultural norms of environmental ethics are examined under Christopher Stone's concept of moral pluralism. G. J. Warnock's notion of the “general object” of morality is proposed to integrate the variegated purposes of environmental ethics.

  13. How Young Children Treat Objects and People: An Empirical Study of the First Year of Life in Autism

    ERIC Educational Resources Information Center

    Maestro, Sandra; Muratori, Filippo; Cavallaro, Maria Cristina; Pecini, Chiara; Cesari, Alessia; Paziente, Antonella; Stern, Daniel; Golse, Bernard; Palacio-Espasa, Francisco

    2005-01-01

    Objective: To figure out features of autism before the age of one and to explore the pathways of early social and nonsocial attention in autism through home movies. Method: Home movies of 15 children later diagnosed with autism, are compared with home movies of 13 typical children. The films of the two groups have been mixed and rated by blind…

  14. The Role of Reachers' Shared Values and Objectives in Promoting Intercultural and Inclusive School Cultures: A Case Study

    ERIC Educational Resources Information Center

    Miravet, Lidon Moliner; García, Odet Moliner

    2013-01-01

    This article presents an analysis of teachers' impressions of their shared objectives and values, together with their conceptions of interculturality and inclusion. The educational reality of a school in Valencia (Spain) is described, based on the exploration through semi-structured interviews. From the systematically categorized information,…

  15. Applying RE-AIM to the evaluation of FUEL Your Life : a worksite translation of DPP.

    PubMed

    Brace, Andrea M; Padilla, Heather M; DeJoy, David M; Wilson, Mark G; Vandenberg, Robert J; Davis, Marsha

    2015-01-01

    Weight management programs are becoming increasingly common in workplace settings; however, few target middle-aged men. The purpose of this article is to describe the process evaluation of a worksite translation of the Diabetes Prevention Program in a predominantly middle-aged male population. The translated program, FUEL Your Life, was largely self-directed, with support from peer health coaches and occupational health nurses. The RE-AIM (Reach Effectiveness Adoption Implementation Maintenance) framework was used to examine the factors that influenced program implementation using data from an environmental assessment, participant surveys, peer health coach surveys, and occupational health nurse interviews. An overwhelming majority of the employees who enrolled in the study were overweight or obese (92%). Overall, the program was effective for weight maintenance; those with higher levels of participation and engagement had better weight loss outcomes. The peer health coach and family elements of the intervention were underused. The program was successful in reaching the intended population; however, the program had limited success in engaging this population. Not surprisingly, weight loss was a function of participant engagement and participation. Increasing participant engagement and participation is important to the success of weight management interventions translated to the worksite setting. Garnering buy-in and support from management can serve to increase the perceived importance of weight management in worksites. With management support, weight management protocols could be integrated as a component of the mandatory safety and health assessments already in place, fostering promotion of healthy weight in the workforce. PMID:24942749

  16. AIM satellite-based research bridges the unique scientific aspects of the mission to informal education programs globally

    NASA Astrophysics Data System (ADS)

    Robinson, D.; Maggi, B.

    2003-04-01

    The Education and Public Outreach (EPO) component of the satellite-based research mission "Aeronomy of Ice In the Mesosphere" (AIM) will bridge the unique scientific aspects of the mission to informal education organizations. The informal education materials developed by the EPO will utilize AIM data and educate the public about the environmental implications associated with the data. This will assist with creating a scientifically literate workforce and in developing a citizenry capable of making educated decisions related to environmental policies and laws. The objective of the AIM mission is to understand the mechanisms that cause Polar Mesospheric Clouds (PMCs) to form, how their presence affects the atmosphere, and how change in the atmosphere affects them. PMCs are sometimes known as Noctilucent Clouds (NLCs) because of their visibility during the night from appropriate locations. The phenomenon of PMCs is an observable indicator of global change, a concern to all citizens. Recent sightings of these clouds over populated regions have compelled AIM educators to expand informal education opportunities to communities worldwide. Collaborations with informal organizations include: Museums/Science Centers; NASA Sun-Earth Connection Forum; Alaska Native Ways of Knowing Project; Amateur Noctilucent Cloud Observers Organization; National Parks Education Programs; After School Science Clubs; Public Broadcasting Associations; and National Public Radio. The Native Ways of Knowing Project is an excellent example of informal collaboration with the AIM EPO. This Alaska based project will assist native peoples of the state with photographing NLCs for the EPO website. It will also aid the EPO with developing materials for informal organizations that incorporate traditional native knowledge and science, related to the sky. Another AIM collaboration that will offer citizens lasting informal education opportunities is the one established with the United States National Parks

  17. Linking Exposure Assessment Science With Policy Objectives for Environmental Justice and Breast Cancer Advocacy: The Northern California Household Exposure Study

    PubMed Central

    Morello-Frosch, Rachel; Zota, Ami; Brown, Phil; Pérez, Carla; Rudel, Ruthann A.

    2009-01-01

    Objectives. We compared an urban fence-line community (neighboring an oil refinery) and a nonindustrial community in an exposure study focusing on pollutants of interest with respect to breast cancer and environmental justice. Methods. We analyzed indoor and outdoor air from 40 homes in industrial Richmond, California, and 10 in rural Bolinas, California, for 153 compounds, including particulates and endocrine disruptors. Results. Eighty compounds were detected outdoors in Richmond and 60 in Bolinas; Richmond concentrations were generally higher. Richmond's vanadium and nickel levels indicated effects of heavy oil combustion from oil refining and shipping; these levels were among the state's highest. In nearly half of Richmond homes, PM2.5 exceeded California's annual ambient air quality standard. Paired outdoor–indoor measurements were significantly correlated for industry- and traffic-related PM2.5, polycyclic aromatic hydrocarbons, elemental carbon, metals, and sulfates (r = 0.54–0.92, P < .001). Conclusions. Indoor air quality is an important indicator of the cumulative impact of outdoor emissions in fence-line communities. Policies based on outdoor monitoring alone add to environmental injustice concerns in communities that host polluters. Community-based participatory exposure research can contribute to science and stimulate and inform action on the part of community residents and policymakers. PMID:19890164

  18. Cross-sectional association of the number of neighborhood facilities assessed using postal code with objectively measured physical activity: the Saku cohort study.

    PubMed

    Yasunaga, Akitomo; Murakami, Haruka; Morita, Akemi; Deura, Kijyo; Aiba, Naomi; Watanabe, Shaw; Miyachi, Motohiko

    2016-01-01

    Objectives The aim of this study was to examine the association between the number of neighborhood facilities that were assessed according to postal code and objectively measured physical activity by using an accelerometer in community-dwelling Japanese people.Methods The participants included 1,274 Japanese people aged 30-84 years from the Saku cohort study. As neighborhood facilities related to physical activity, we extracted information regarding train stations, supermarkets/convenience stores, postal offices/banks, hospitals/clinics, public offices/community centers, cultural facilities/public children's houses, parks, and sports facilities by using each participant's postal code from the online version of the iTownPages directory published by Nippon Telegraph and Telephone Corporation (NTT) and the official homepage of the Saku City Government Office. We measured each participant's physical activity level using an accelerometer, and calculated the average daily step count and the average weekly period of moderate-to-vigorous intensity (≥3 metabolic equivalents of tasks [METs]) physical activity. The association between two selected physical activity-related variables and the numbers of eight types of neighborhood facilities were analyzed by multivariate logistic regression analysis for people aged 30-64 years and for those aged over 65 years.Results On multivariate logistic regression analysis, meeting the 23 METs h/week of moderate-to-vigorous intensity physical activity was significantly and positively associated with the number of supermarkets/convenience stores in the neighborhood in both age groups. In addition, meeting the desired daily step count outlined in the Japanese National Health Promotion guidelines was positively related to the number of postal offices/banks for people aged over 65 years.Conclusion The results of this study suggest that a sufficient number of neighborhood facilities (i.e., stores, banks, and postal offices) is closely

  19. Telehealth and Occupational Therapy: Integral to the Triple Aim of Health Care Reform.

    PubMed

    Cason, Jana

    2015-01-01

    Programs and concepts included in the Patient Protection and Affordable Care Act of 2010 are expected to transform health care in the United States from a volume-based health system to a value-based health system with increased emphasis on prevention and health promotion. The Triple Aim, a framework set forth by the Institute for Healthcare Improvement, focuses on improving the health care experience, the health of populations, and the affordability of care. This article describes telehealth as an integral component in achieving the Triple Aim of health care and discusses implications for occupational therapy practitioners. PMID:26122676

  20. Methodology and Results of the Near-Earth Object (NEO) Human Space Flight (HSF) Accessible Targets Study (NHATS)

    NASA Technical Reports Server (NTRS)

    Barbee, Brent; Mink, Ronald; Adamo, Daniel

    2011-01-01

    Near-Earth Asteroids (NEAs) have been identified by the current administration as potential destinations for human explorers during the mid-2020s. While the close proximity of these objects' orbits to Earth's orbit creates a risk of highly damaging or catastrophic impacts, it also makes some of these objects particularly accessible to spacecraft departing Earth, and this presents unique opportunities for solar system science and humanity's first ventures beyond cislunar space. Planning such ambitious missions first requires the selection of potentially accessible targets from the growing population of nearly 7,800 NEAs. To accomplish this, NASA is conducting the Near-Earth Object (NEO) Human Space Flight (HSF) Accessible Targets Study (NHATS). Phase I of the NHATS was executed during September of 2010, and Phase II was completed by early March of 2011. The study is ongoing because previously undetected NEAs are being discovered constantly, which has motivated an effort to automate the analysis algorithms in order to provide continuous monitoring of NEA accessibility. The NHATS analysis process consists of a trajectory filter and a minimum maximum estimated size criterion. The trajectory filter employs the method of embedded trajectory grids to compute all possible ballistic round-trip mission trajectories to every NEA in the Jet Propulsion Laboratory (JPL) Small-Body Database (SBDB) and stores all solutions that satisfy the trajectory filter criteria. An NEA must offer at least one qualifying trajectory solution to pass the trajectory filter. The Phase II NHATS filter criteria were purposely chosen to be highly inclusive, requiring Earth departure date between January 1st, 2015 and December 31st, 2040, total round-trip flight time <= 450 days, stay time at the NEA >= 8 days, Earth departure C(sub 3) energy <= 60 km(exp 2)/s(exp 2), total mission delta-v <= 12 km/s (including an Earth departure maneuver from a 400 km altitude circular parking orbit), and a maximum

  1. A Descriptive Study of the Pilot Implementation of Student Learning Objectives in Arizona and Utah. REL 2016-102

    ERIC Educational Resources Information Center

    Makkonen, Reino; Tejwani, Jaclyn; Rodriguez, Fernando, Jr.

    2015-01-01

    Approximately 30 states are now adopting teacher evaluation policies that include student learning objectives (SLOs), which are classroom-specific student test growth targets set by teachers and approved (and scored) by principals. Today state and district leaders are trying to determine the appropriate level of guidance and oversight to provide…

  2. ASSOCIATION BETWEEN THYROID FUNCTION AND OBJECTIVE AND SUBJECTIVE SLEEP QUALITY IN OLDER MEN: THE OSTEOPOROTIC FRACTURES IN MEN (MROS) STUDY

    PubMed Central

    Akatsu, Haruko; Ewing, Susan K.; Stefanick, Marcia L.; Fink, Howard A.; Stone, Katie L.; Barrett-Connor, Elizabeth; Mehra, Reena; Ancoli-Israel, Sonia; Redline, Susan; Hoffman, Andrew R.

    2014-01-01

    Objective To determine the association between thyroid hormone levels and sleep quality in community-dwelling men. Methods Among 5,994 men aged ≥65 years in the Osteoporotic Fractures in Men (MrOS) study, 682 had baseline thyroid function data, normal free thyroxine (FT4) (0.70 ≤ FT4 ≤ 1.85 ng/dL), actigraphy measurements, and were not using thyroid-related medications. Three categories of thyroid function were defined: subclinical hyperthyroid, thyroid-stimulating hormone (TSH) <0.55 mIU/L; euthyroid (TSH, 0.55 to 4.78 mIU/L); and subclinical hypothyroid (TSH >4.78 mIU/L). Objective (total hours of nighttime sleep [TST], sleep efficiency [SE], wake after sleep onset [WASO], sleep latency [SL], number of long wake episodes [LWEP]) and subjective (TST, Pittsburgh Sleep Quality Index score, Epworth Sleepiness Scale score) sleep quality were measured. The association between TSH and sleep quality was examined using linear regression (continuous sleep outcomes) and log-binomial regression (categorical sleep outcomes). Results Among the 682 men examined, 15 had subclinical hyperthyroidism and 38 had subclinical hypothyroidism. There was no difference in sleep quality between subclinical hypothyroid and euthyroid men. Compared to euthyroid men, subclinical hyperthyroid men had lower mean actigraphy TST (adjusted mean difference [95% confidence interval (CI)], −27.4 [−63.7 to 8.9] minutes) and lower mean SE (−4.5% [−10.3% to 1.3%]), higher mean WASO (13.5 [−8.0 to 35.0] minutes]), whereas 41% had increased risk of actigraphy-measured TST <6 hours (relative risk [RR], 1.41; 95% CI, 0.83 to 2.39), and 83% had increased risk of SL ≥60 minutes (RR, 1.83; 95% CI, 0.65 to 5.14) (all P>0.05). Conclusion Neither subclinical hypothyroidism nor hyperthyroidism is significantly associated with decreased sleep quality. PMID:24449663

  3. [Remission and recovery: new hopes--realistic aims in the therapy for schizophrenia].

    PubMed

    Schöttle, D; Naber, D

    2014-04-01

    The present review critically appraises the various different definitions of and the ongoing discussions about the terms remission and recovery, which represent important aspects for describing the disease course, therapy planning and the setting of therapeutic targets for the patient, relatives and the professional care-giver. A symptomatic remission is well defined and is reached by about 30-60% of the first-time patients. However, this is not to be equated with functional, social and subjective remission. The term recovery has various definitions and has as yet only been studied in a relatively unempirical manner but represents an important supplement to the often strictly formulated therapeutic targets that need to be complemented by subjective and objective as well as personal and clinical perspectives. To inspire and maintain hope is thus an essential factor that extends beyond the therapeutic target of an often rather resigning symptomatic therapy. Even so, the provision of hope remains a balancing act. Too little hope can induce pessimism which in turn may have considerable negative therapeutic and personal consequences. On the other hand an uncritical attitude to hope may lead to unrealistic expectations--inevitably to be followed by frustration and resignation again. PMID:24710678

  4. Globalization and the Asia Pacific: An Exploration of Efficiency and Equality Aims of Education

    ERIC Educational Resources Information Center

    Engel, Laura C.; Rutkowski, David J.

    2008-01-01

    The paper aims to explore the relationship between globalization and education through an investigation of educational policy development in the specific context of the Asia Pacific. The paper's primary focus is on data collected from the World Bank, OECD, IMF and UNESCO to look primarily at three interrelated trends in education: increasing…

  5. Value of Information Analysis Applied to the Economic Evaluation of Interventions Aimed at Reducing Juvenile Delinquency: An Illustration

    PubMed Central

    Eeren, Hester V.; Schawo, Saskia J.; Scholte, Ron H. J.; Busschbach, Jan J. V.; Hakkaart, Leona

    2015-01-01

    Objectives To investigate whether a value of information analysis, commonly applied in health care evaluations, is feasible and meaningful in the field of crime prevention. Methods Interventions aimed at reducing juvenile delinquency are increasingly being evaluated according to their cost-effectiveness. Results of cost-effectiveness models are subject to uncertainty in their cost and effect estimates. Further research can reduce that parameter uncertainty. The value of such further research can be estimated using a value of information analysis, as illustrated in the current study. We built upon an earlier published cost-effectiveness model that demonstrated the comparison of two interventions aimed at reducing juvenile delinquency. Outcomes were presented as costs per criminal activity free year. Results At a societal willingness-to-pay of €71,700 per criminal activity free year, further research to eliminate parameter uncertainty was valued at €176 million. Therefore, in this illustrative analysis, the value of information analysis determined that society should be willing to spend a maximum of €176 million in reducing decision uncertainty in the cost-effectiveness of the two interventions. Moreover, the results suggest that reducing uncertainty in some specific model parameters might be more valuable than in others. Conclusions Using a value of information framework to assess the value of conducting further research in the field of crime prevention proved to be feasible. The results were meaningful and can be interpreted according to health care evaluation studies. This analysis can be helpful in justifying additional research funds to further inform the reimbursement decision in regard to interventions for juvenile delinquents. PMID:26146831

  6. A Formative Evaluation Plan for the Automated Instructional Management System (AIMS).

    ERIC Educational Resources Information Center

    Berkowitz, Melissa; And Others

    The plan described was developed to evaluate the training and cost-effectiveness of the Automated Instructional Management System (AIMS), a computer-based training and resource development system being developed by the Training and Doctrine Command (TRADOC) for possible installation in its schools and training centers. The Functional Description…

  7. The Subsequent Dissemination of Material Presented in Sessions of the Metallurgical Society at the 96th AIME Annual Meeting.

    ERIC Educational Resources Information Center

    Johns Hopkins Univ., Baltimore, MD. Center for Research in Scientific Communication.

    Studies of 255 authors of program material at the Metallurgical Society session of the 96th American Institute of Mining, Metallurgical, and Petroleum Engineers (AIME) Annual Meeting yielded data on the subsequent dissemination of presented material during the year following the meeting. Data showed that three-fourths of the authors who made…

  8. Theoretical investigation of hydrogen bonding between water and platinum(II): an atom in molecule (AIM) study

    NASA Astrophysics Data System (ADS)

    Li, Yan; Zhang, Guiqiu; Chen, Dezhan

    2012-02-01

    Recently, Rizzato et al. [Angew. Chem. Int. Ed. 49, 7440 (2010)] [1] reported a hydrogen-bonding-like interaction between a water molecule and a d8 metal ion (PtII) based on neutron diffraction, and provided the first crystallographic evidence for this interaction. We studied the hydrogen bonding of the O-H ... Pt interaction theoretically using atoms in molecule (AIM) and natural bond orbital analysis (NBO) in the crystallographic geometries. The method used density functional theory (DFT) with the hybrid B3LYP function. For platinum atoms, we used the Los Alamos National Laboratory 2-Double-Zeta (LANL2DZ) basis set, and for the other atoms we used 6-311++G(d,p) basis sets. Criteria based on a topological analysis of the electron density were used in order to characterize the nature of interactions in the complexes. The main purpose of the present work is to provide an answer to the following questions: Why can a filled d orbital of square-planar d8 metal ions such as platinum(II) also act as hydrogen-bond acceptors? Can a study based on the electron charge density answer this question? A good correlation between the density at the intermolecular bond critical point and the energy interaction was found. The interaction is mainly closed-shell and there is some charge transfer in this system.

  9. Guiding the Design of Lessons by Using the MAPLET Framework: Matching Aims, Processes, Learner Expertise and Technologies

    ERIC Educational Resources Information Center

    Ifenthaler, Dirk; Gosper, Maree

    2014-01-01

    This paper introduces the MAPLET framework that was developed to map and link teaching aims, learning processes, learner expertise and technologies. An experimental study with 65 participants is reported to test the effectiveness of the framework as a guide to the design of lessons embedded within larger units of study. The findings indicate the…

  10. An Economic Aspect of the AVOID Programme: Analysis Using the AIM/CGE Model

    NASA Astrophysics Data System (ADS)

    Matsumoto, Ken'ichi; Masui, Toshihiko

    2010-05-01

    This presentation purposes to show the results of the analysis that the AIM/CGE [Global] model contributed to Work Stream 1 of the AVOID programme. Three economic models participate in this WS to analyze the economic aspects of defined climate policies, and the AIM/CGE [Global] model is one of them. The reference scenario is SRES A1B and five policy scenarios (2016.R2.H, 2016.R4.L, 2016.R5.L, 2030.R2.H, and 2030.R5.L) are considered. The climate policies are expressed as emissions pathways of several gases such as greenhouse gases and aerosols. The AIM/CGE [Global] model is a recursive dynamic global CGE model with 21 industrial sectors and 24 world regions. These definitions are based on the GTAP6 database and it is used as the economic data of the base year. Some important characteristics of this model can be summarized as follows: power generation by various sources (from non-renewables to renewables) are considered; CCS technology is modeled; biomass energy (both traditional and purpose-grown) production and consumption are included; not only CO2 emissions but also other gases are considered; international markets are modeled for international trade of some fossil fuels; relationships between the costs and resource reserves of fossil fuels are modeled. The model is run with 10-year time steps until 2100. For the reference case, there are no constraints and the model is run based on the drivers (assumptions on GDP and population for A1B) and AEEI. The reference case does not have the same emissions pathways as the prescribed emissions for A1B in AVOID. For scenario cases, the model is run under emissions constraints. In particular, for each policy scenario, the constraint on each gas in each 10-year step is derived. The percentage reduction in emissions that occurs between the AVOID A1B scenario and the particular policy scenario, for each gas in each 10-year period is first calculated, and then these percentage reductions are applied to the AIM reference case

  11. Optical and photometric studies of Earth orbiting small space objects

    NASA Astrophysics Data System (ADS)

    Selim, I. M.; El-Hameed, Afaf M. Abd; Bakhtigaraev, N. S.; Attia, Gamal F.

    2016-03-01

    Variations of light curves for space objects are investigated. Optical observations and photometric measurements for small space debris on highly elliptical orbits (HEO) and geostationary orbits (GEO) are used to determine their orbital parameters. Light curves of small space debris with various area-to-mass ratios and orbital characteristics are discussed. Tracking of some objects shows very rapid brightness variations related to perturbations of the orbital parameters. Changes in brightness and equatorial coordinates of the studied objects are found in observational data. Our results allow improving the accuracy of space debris orbital elements.

  12. The gravitational wave signal from isolated objects

    NASA Astrophysics Data System (ADS)

    Liu, Jinzhong; Zhang, Yu

    2013-02-01

    According to the theoretical study, a deformation object (e.g., a spinning non-axisymmetric pulsar star) will radiate a gravitational wave (GW) signal during an accelaration motion process by LIGO science project. These types of disturbance sources with a large bump or dimple on the equator would survive and be identifiable as GW sources. In this work, we aim to provide a method for exploring GW radiation from isolated neutron stars (NSs) with deformation state using some observational results, which can be confirmed by the next LIGO project. Combination with the properties in observation results (e.g., PSR J1748-2446, PSR 1828-11 and Cygnus X-1), based on a binary population synthesis (BPS) approach we give a numerical GW radiation under the assumption that NS should have non-axisymmetric and give the results of energy spectrum. We find that the GW luminosity of LGW can be changed from about 1040 erg/s - 1055 erg/s.

  13. AIM-Monitoring: a component of the BLM assessment, inventory, and monitoring strategy

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The “BLM Assessment, Inventory, and Monitoring Strategy for Integrated Renewable Resources Management” (AIM Strategy) was completed in 2011 in response to a request from the Office of Management and Budget. The strategy describes an approach for integrated, cross-program assessment, inventory, and m...

  14. THE OBJECT-PRESERVING FUNCTION OF SADOMASOCHISM.

    PubMed

    Grossman, Lee

    2015-07-01

    The terms sadism, masochism, and sadomasochism seem to have become increasingly, if loosely, associated with aggression in psychoanalytic discourse. This is due in part to the fact that Freud's changing ideas generated confusion about the relative contributions of libido and aggression. The author reviews Freud's variable usage and offers a clinical vignette to illustrate the importance of noticing how sadomasochism may maintain a tie to the object by controlling it. The author offers a developmental speculation for the role reversibility typical of sadomasochistic manifestations. He closes with a comment on the role of sadomasochistic aims in adult sexual perversion. PMID:26198604

  15. The Role of Field Education in a University-Community Partnership Aimed at Curriculum Transformation

    ERIC Educational Resources Information Center

    Lewis, Laura A.; Kusmaul, Nancy; Elze, Diane; Butler, Lisa

    2016-01-01

    University-community partnerships can play an important role in curriculum development, but little has been written about the role of community agencies in designing curricula. This article describes the role of field education in an innovative university-community partnership aimed at transforming an MSW curriculum to integrate a trauma-informed…

  16. R. S. Peters and J. H. Newman on the Aims of Education

    ERIC Educational Resources Information Center

    Ozolins, Janis T.

    2013-01-01

    R. S. Peters never explicitly talks about wisdom as being an aim of education. He does, however, in numerous places, emphasize that education is of the whole person and that, whatever else it might be about, it involves the development of knowledge and understanding. Being educated, he claims, is incompatible with being narrowly specialized.…

  17. Evaluating the public health impact of health promotion interventions: the RE-AIM framework.

    PubMed Central

    Glasgow, R E; Vogt, T M; Boles, S M

    1999-01-01

    Progress in public health and community-based interventions has been hampered by the lack of a comprehensive evaluation framework appropriate to such programs. Multilevel interventions that incorporate policy, environmental, and individual components should be evaluated with measurements suited to their settings, goals, and purpose. In this commentary, the authors propose a model (termed the RE-AIM model) for evaluating public health interventions that assesses 5 dimensions: reach, efficacy, adoption, implementation, and maintenance. These dimensions occur at multiple levels (e.g., individual, clinic or organization, community) and interact to determine the public health or population-based impact of a program or policy. The authors discuss issues in evaluating each of these dimensions and combining them to determine overall public health impact. Failure to adequately evaluate programs on all 5 dimensions can lead to a waste of resources, discontinuities between stages of research, and failure to improve public health to the limits of our capacity. The authors summarize strengths and limitations of the RE-AIM model and recommend areas for future research and application. PMID:10474547

  18. The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA.

    PubMed

    Gray, Elizabeth E; Winship, Damion; Snyder, Jessica M; Child, Stephanie J; Geballe, Adam P; Stetson, Daniel B

    2016-08-16

    Detection of intracellular DNA triggers activation of the STING-dependent interferon-stimulatory DNA (ISD) pathway, which is essential for antiviral responses. Multiple DNA sensors have been proposed to activate this pathway, including AIM2-like receptors (ALRs). Whether the ALRs are essential for activation of this pathway remains unknown. To rigorously explore the function of ALRs, we generated mice lacking all 13 ALR genes. We found that ALRs are dispensable for the type I interferon (IFN) response to transfected DNA ligands, DNA virus infection, and lentivirus infection. We also found that ALRs do not contribute to autoimmune disease in the Trex1(-/-) mouse model of Aicardi-Goutières Syndrome. Finally, CRISPR-mediated disruption of the human AIM2-like receptor IFI16 in primary fibroblasts revealed that IFI16 is not essential for the IFN response to human cytomegalovirus infection. Our findings indicate that ALRs are dispensable for the ISD response and suggest that alternative functions for these receptors should be explored. PMID:27496731

  19. Social Studies at the Beginning of the New Millennium: Teach Democratic Ideals, Geography, and History or Is that Objective Outdated?

    ERIC Educational Resources Information Center

    De Villier, Paul Wayne

    Although many pressures have been brought to bear in the social studies curriculum over the past 70 years, the leaders of the country's society have maintained the middle ground. They have ensured that educators remain somewhat conservative in their approach to the social sciences, ensuring that the history of the culture be continually passed on…

  20. Simpozionul Pregatirea Pentru Munca Obiectiv al Invatamintului (Symposium on Training for Work, the Aim of Education).

    ERIC Educational Resources Information Center

    Barbulescu, Petre, Ed.

    Educational reform in Rumania at the elementary, secondary, and university levels has led to a greater emphasis on vocational-technical training and toward promoting further socialist attitudes among all students. The new educational objectives were outlined in a symposium on vocational training in which over 200 Rumanian educators participated.…

  1. 'The thieving magpie'? No evidence for attraction to shiny objects.

    PubMed

    Shephard, T V; Lea, S E G; Hempel de Ibarra, N

    2015-01-01

    It is widely accepted in European culture that magpies (Pica pica) are unconditionally attracted to shiny objects and routinely steal small trinkets such as jewellery, almost as a compulsion. Despite the long history of this folklore, published accounts of magpies collecting shiny objects are rare and empirical evidence for the behaviour is lacking. The latter is surprising considering that an attraction to bright objects is well documented in some bird species. The present study aims to clarify whether magpies show greater attraction to shiny objects than non-shiny objects when presented at the same time. We did not find evidence of an unconditional attraction to shiny objects in either captive or free-living birds. Instead, all objects elicited responses indicating neophobia in free-living birds. We suggest that humans notice when magpies occasionally pick up shiny objects because they believe the birds find them attractive, while it goes unnoticed when magpies interact with less eye-catching items. The folklore may therefore result from observation bias and cultural inflation of orally transmitted episodic events. PMID:25123853

  2. Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection

    PubMed Central

    Karki, Rajendra; Man, Si Ming; Malireddi, R.K. Subbarao; Gurung, Prajwal; Vogel, Peter; Lamkanfi, Mohamed; Kanneganti, Thirumala-Devi

    2015-01-01

    SUMMARY Invasive pulmonary aspergillosis is a leading cause of infection-associated mortality in immunocompromised individuals. Aspergillus fumigatus infection produces ligands that could activate inflammasomes but the contribution of these host defenses remains unclear. We show that two inflammasome receptors, AIM2 and NLRP3, recognize intracellular A. fumigatus and collectively induce protective immune responses. Mice lacking both AIM2 and NLRP3 fail to confine Aspergillus hyphae to inflammatory foci, leading to widespread hyphal dissemination to lung blood vessels. These mice succumb to infection more rapidly than WT mice or mice lacking a single inflammasome receptor. AIM2 and NLRP3 activation initiates assembly of a single cytoplasmic inflammasome platform, composed of the adaptor protein ASC along with caspase-1 and caspase-8. Combined actions of caspase-1 and caspase-8 lead to processing of proinflammatory cytokines IL-1β and IL-18 that critically control the infection. Thus, AIM2 and NLRP3 form a dual cytoplasmic surveillance system that orchestrates responses against A. fumigatus infection. PMID:25704009

  3. THE PERVERSITY OF INANIMATE OBJECTS

    PubMed Central

    Levine, Lindsay R.; Morsella, Ezequiel; Bargh, John A.

    2008-01-01

    Social cognition research suggests that incidental, environmental stimuli (e.g., business suits) can nonconsciously influence the degree to which behavioral dispositions (e.g., competitiveness) are expressed. Similarly, cognitive research suggests that incidental action-related objects (e.g., hammers) can prime action plans that then affect the speed with which a concurrent, intended action (e.g., power grip) is executed. However, whether incidental stimuli can instigate actions that run counter to one’s current goals has yet to be determined. Moving beyond indirect effects, we show that such stimuli can directly cause the expression of undesired actions: Incidental stimuli resembling musical notation caused the systematic expression of unintended key presses in musicians, but not in nonmusicians. Moreover, the effect was found even when targets and distracters bore no apparent perceptual or semantic relation. We discuss the implications of these findings for models of action production and for social-cognitive concepts (e.g., applicability) regarding the limits of nonconscious processing. PMID:18509502

  4. Special report on the political and social contexts of health: Part I. Introduction: objectives and purposes of the study.

    PubMed

    Navarro, Vicente

    2003-01-01

    This article introduces a series of research projects (carried out by the International Network on Social Inequalities and Health) focused on the impact of politics on policy and the consequences for health and quality of life, an area that has been understudied in the social science literature. The introduction describes the conceptual model that guided the research, centered on the study of how political parties and social agents (such as trade unions) affect social inequalities and mortality indicators through labor market and welfare state policies. The major theme of this research is whether political and social interventions matter in health policy and health outcomes. The introduction also describes the different types of research projects carried out by the International Network at the national levels (among OECD countries) and at the regional and local levels (in the United Kingdom, Italy, Germany, Spain, and Sweden). This Journal issue presents the multinational study and the U.K. case study; the next issue will include the Italian, German, Spanish, and Swedish case studies and the summary and conclusions. PMID:14582868

  5. A comparative study of objective and subjective assessment of occupational risk.

    PubMed

    Koradecka, Danuta; Pośniak, Małgorzata; Widerszal-Bazyl, Maria; Augusty Nska, Danuta; Radkiewicz, Piotr

    2010-01-01

    Measurement of dangerous, harmful and annoying factors in the working environment are used to assess occupational risk. Surveys on workers' subjective perception of risk are used, too. This study aimed to compare subjective assessment of work-related factors with their objective measurements and a national database on occupational risk. Spearman's correlation analysis, stepwise regression analysis and structural modelling were used to determine the relationship between subjective and objective risk assessment and to acquire knowledge about the role of psychosocial job characteristics as predictors of subjective assessment. Subjective assessment of hazards was related not only to their objective measurements but also to psychosocial job characteristics, workers' individual characteristics and work load. Even though subjective and objective assessments of hazard are strongly related, they are distinct phenomena. Hence, risk assessment should be carried out with both objective and subjective methods. PMID:20331915

  6. Fibreoptic fluorescent microscopy in studying biological objects

    SciTech Connect

    Morozov, A N; Turchin, Il'ya V; Kamenskii, V A; Fiks, I I; Lazutkin, A A; Bezryadkov, D V; Ivanova, A A; Toptunov, D M; Anokhin, K V

    2010-11-13

    The method of fluorescent microscopy is developed based on employment of a single-mode fibreoptic channel to provide high spatial resolution 3D images of large cleared biological specimens using the 488-nm excitation laser line. The transverse and axial resolution of the setup is 5 and 13 {mu}m, respectively. The transversal sample size under investigation is up to 10 mm. The in-depth scanning range depends on the sample transparency and reaches 4 mm in the experiment. The 3D images of whole mouse organs (heart, lungs, brain) and mouse embryos obtained using autofluorescence or fluorescence of exogenous markers demonstrate a high contrast and cellular-level resolution.

  7. Object Based Image Analysis to Support Environmental Monitoring Under the European Habitat Directive: a Case Study from Decover

    NASA Astrophysics Data System (ADS)

    Buck, O.; Peter, B.; Völker, A.; Donning, A.

    2011-09-01

    DeCOVER serves as a national extension of the European Global Monitoring for Environment and Security (GMES) initiative. It was initiated to develop land cover information services adapted to German user needs. One of its three service developments pillars is the application of Remote Sensing to support environmental monitoring schemes under the European Habitats Directive.Within two DeCOVER test sites located in North-Rhine Westphalia/Germany an object-based indicator classification approach is currently being developed to monitor heath habitats of importance under the Habitats Directive. While many previous Remote Sensing projects have focused on the discrete classification of habitat types to replace fieldwork, our approach is embedded in a strong operational context to a) focus and direct fieldwork efforts by pre-field visit assessment of habitat changes (change detection) and b) support fieldwork by contributing quality parameters and GIS-ready geometries. Using Geoeye satellite data (VHR component) and RapidEye satellite images (Multi-temporal HR component) together with existing habitat and biotope maps (knowledge and post-classification component) an image analysis approach is realised using object-based classification routines based on data mining tools to derive training information. To extract meaningful objects of heath-, sand- and grassland from the VHR-data, training sample areas have to be assigned. Thresholds and appropriate features for describing these samples are analysed by statistical algorithms and are used in the following classification. A multi-temporal approach for the acquisition of tree habitat areas integrates two RapidEye scenes into the classification process. To validate classification accuracies and potential transects were sampled in the field and analyzed for their structural composition using top view field photos of 1m2. First results demonstrate the realistic option to directly support the fieldwork or reduce its post

  8. Advances with the new AIMS fab 193 2nd generation: a system for the 65 nm node including immersion

    NASA Astrophysics Data System (ADS)

    Zibold, Axel M.; Poortinga, E.; Doornmalen, H. v.; Schmid, R.; Scherubl, T.; Harnisch, W.

    2005-06-01

    The Aerial Image Measurement System, AIMS, for 193nm lithography emulation is established as a standard for the rapid prediction of wafer printability for critical structures including dense patterns and defects or repairs on masks. The main benefit of AIMS is to save expensive image qualification consisting of test wafer exposures followed by wafer CD-SEM resist or wafer analysis. By adjustment of numerical aperture (NA), illumination type and partial coherence (σ) to match any given stepper/ scanner, AIMS predicts the printability of 193nm reticles such as binary with, or without OPC and phase shifting. A new AIMS fab 193 second generation system with a maximum NA of 0.93 is now available. Improvements in field uniformity, stability over time, measurement automation and higher throughput meet the challenging requirements of the 65nm node. A new function, "Global CD Map" can be applied to automatically measure and analyse the global CD uniformity of repeating structures across a reticle. With the options of extended depth-of-focus (EDOF) software and the upcoming linear polarisation capability in the illumination the new AIMS fab 193 second generation system is able to cover both dry and immersion requirements for NA < 1. Rigorous simulations have been performed to study the effects of polarisation for imaging by comparing the aerial image of the AIMS to the resist image of the scanner.

  9. Attachment to inanimate objects and early childcare: A twin study

    PubMed Central

    Fortuna, Keren; Baor, Liora; Israel, Salomon; Abadi, Adi; Knafo, Ariel

    2014-01-01

    Extensive non-maternal childcare plays an important role in children’s development. This study examined a potential coping mechanism for dealing with daily separation from caregivers involved in childcare experience – children’s development of attachments toward inanimate objects. We employed the twin design to estimate relative environmental and genetic contributions to the presence of object attachment, and assess whether childcare explains some of the environmental variation in this developmental phenomenon. Mothers reported about 1122 3-year-old twin pairs. Variation in object attachment was accounted for by heritability (48%) and shared environment (48%), with childcare quantity accounting for 2.2% of the shared environment effect. Children who spent half-days in childcare were significantly less likely to attach to objects relative to children who attended full-day childcare. PMID:24904499

  10. Object-Based Greenhouse Classification from High Resolution Satellite Imagery: a Case Study Antalya-Turkey

    NASA Astrophysics Data System (ADS)

    Coslu, M.; Sonmez, N. K.; Koc-San, D.

    2016-06-01

    Pixel-based classification method is widely used with the purpose of detecting land use and land cover with remote sensing technology. Recently, object-based classification methods have begun to be used as well as pixel-based classification method on high resolution satellite imagery. In the studies conducted, it is indicated that object-based classification method has more successful results than other classification methods. While pixel-based classification method is performed according to the grey value of pixels, object-based classification process is executed by generating imagery segmentation and updatable rule sets. In this study, it was aimed to detect and map the greenhouses from object-based classification method by using high resolution satellite imagery. The study was carried out in the Antalya province which includes greenhouse intensively. The study consists of three main stages including segmentation, classification and accuracy assessment. At the first stage, which was segmentation, the most important part of the object-based imagery analysis; imagery segmentation was generated by using basic spectral bands of high resolution Worldview-2 satellite imagery. At the second stage, applying the nearest neighbour classifier to these generated segments classification process was executed, and a result map of the study area was generated. Finally, accuracy assessments were performed using land studies and digital data of the area. According to the research results, object-based greenhouse classification using high resolution satellite imagery had over 80% accuracy.

  11. The influence of visual feedback and prior knowledge about feedback on vertical aiming strategies.

    PubMed

    Elliott, Digby; Dutoy, Chris; Andrew, Matthew; Burkitt, James J; Grierson, Lawrence E M; Lyons, James L; Hayes, Spencer J; Bennett, Simon J

    2014-01-01

    Two experiments were conducted to examine time and energy optimization strategies for movements made with and against gravity. In Experiment 1, the authors manipulated concurrent visual feedback, and knowledge about feedback. When vision was eliminated upon movement initiation, participants exhibited greater undershooting, both with their primary submovement and their final endpoint, than when vision was available. When aiming downward, participants were more likely to terminate their aiming following the primary submovement or complete a lower amplitude corrective submovement. This strategy reduced the frequency of energy-consuming corrections against gravity. In Experiment 2, the authors eliminated vision of the hand and the target at the end of the movement. This procedure was expected to have its greatest impact under no-vision conditions where no visual feedback was available for subsequent planning. As anticipated, direction and concurrent visual feedback had a profound impact on endpoint bias. Participants exhibited pronounced undershooting when aiming downward and without vision. Differences in undershooting between vision and no vision were greater under blocked feedback conditions. When performers were uncertain about the impending feedback, they planned their movements for the worst-case scenario. Thus movement planning considers the variability in execution, and avoids outcomes that require time and energy to correct. PMID:25204201

  12. A Study of the Effects of Underlying Assumptions in the Reduction of Multi-Object Photometry of Transiting Exoplanets

    NASA Astrophysics Data System (ADS)

    Ryleigh Fitzpatrick, M.; Pearson, Kyle; Griffith, Caitlin Ann; Dunn, Marina; Montiel, Nicholas John; Zellem, Robert T.; Calahan, Jenny; Chance, Quadry; Henrici, Andrew; Sanchez, Dominic; AzGOE

    2016-01-01

    The analysis of ground-based photometric observations of planetary transits must treat the effects of the Earth's atmosphere, which exceed the signal of the extrasolar planet. Generally, this is achieved by dividing the signal of the host star and planet from that of nearby field stars. For bright hot Jupiter exoplanets this procedure reveals the lightcurve. The lightcurve is then fit to a model of the planet's orbit and the physical characteristics, also taking into account the characteristics of the star. The fit to the in-transit data coupled with the fit of the out-of-transit data establish the depth of the lightcurve.The question then arises, what is the best way to select and treat the reference stars such that we can best characterize and remove the shared atmospheric systematics that plague our transit signal. To explore these questions we examine the effects of several assumptions that underline the calculation of the light curve depth. Our study involves photometric observations of hot Jupiter primary transits in the U and B filters taken with the University of Arizona's Kuiper 1.55m telescope and Mont4K CCD. The data consists of repeated transit observations of a variety of exoplanets, each of which offers a unique field with stars of various brightness, spectral types, and angular distance from the host star. While these observations are part of a larger study of the Rayleigh scattering signature of hot Jupiter exoplanets, here we study the effects of various choices during the reduction phase, specifically the treatment of the reference stars and atmospheric systematics. Our study calculates the lightcurve for all permutations of the reference stars, considering several different out-of-transit assumptions (e.g. linear, quadratic or exponential). We assess the sensitivity of the transit depths based on the spread of the values and look for characteristics that minimize the scatter in the reduced lightcurve as well as analyze the effects of the

  13. Cardiovascular disease, risk factors and heart rate variability in the elderly general population: Design and objectives of the CARdiovascular disease, Living and Ageing in Halle (CARLA) Study

    PubMed Central

    Greiser, Karin H; Kluttig, Alexander; Schumann, Barbara; Kors, Jan A; Swenne, Cees A; Kuss, Oliver; Werdan, Karl; Haerting, Johannes

    2005-01-01

    Background The increasing burden of cardiovascular diseases (CVD) in the ageing population of industrialized nations requires an intensive search for means of reducing this epidemic. In order to improve prevention, detection, therapy and prognosis of cardiovascular diseases on the population level in Eastern Germany, it is necessary to examine reasons for the East-West gradient of CVD morbidity and mortality, potential causal mechanisms and prognostic factors in the elderly. Psychosocial and nutritional factors have previously been discussed as possible causes for the unexplained part of the East-West gradient. A reduced heart rate variability appears to be associated with cardiovascular disease as well as with psychosocial and other cardiovascular risk factors and decreases with age. Nevertheless, there is a lack of population-based data to examine the role of heart rate variability and its interaction with psychosocial and nutritional factors regarding the effect on cardiovascular disease in the ageing population. There also is a paucity of epidemiological data describing the health situation in Eastern Germany. Therefore, we conduct a population-based study to examine the distribution of CVD, heart rate variability and CVD risk factors and their associations in an elderly East German population. This paper describes the design and objectives of the CARLA Study. Methods/design For this study, a random sample of 45–80 year-old inhabitants of the city of Halle (Saale) in Eastern Germany was drawn from the population registry. By the end of the baseline examination (2002–2005), 1750 study participants will have been examined. A multi-step recruitment strategy aims at achieving a 70 % response rate. Detailed information is collected on own and family medical history, socioeconomic, psychosocial, behavioural and biomedical factors. Medical examinations include anthropometric measures, blood pressure of arm and ankle, a 10-second and a 20-minute electrocardiogram

  14. A Multi-Component Model for Assessing Learning Objects: The Learning Object Evaluation Metric (LOEM)

    ERIC Educational Resources Information Center

    Kay, Robin H.; Knaack, Liesel

    2008-01-01

    While discussion of the criteria needed to assess learning objects has been extensive, a formal, systematic model for evaluation has yet to be thoroughly tested. The purpose of the following study was to develop and assess a multi-component model for evaluating learning objects. The Learning Object Evaluation Metric (LOEM) was developed from a…

  15. Social Studies Subgoals and Suggested Essential Student Objectives.

    ERIC Educational Resources Information Center

    Texas Education Agency, Austin. Div. of Curriculum Development.

    The document outlines specific goals of a social studies program (K-12) that are consistent with the generalized goals for education of the State Board of Education in Texas. Prior to presenting these goals, the purposes, method of development of the objectives, and the goals for public school education are outlined. General goals are categorized…

  16. Precision laser aiming system

    SciTech Connect

    Ahrens, Brandon R.; Todd, Steven N.

    2009-04-28

    A precision laser aiming system comprises a disrupter tool, a reflector, and a laser fixture. The disrupter tool, the reflector and the laser fixture are configurable for iterative alignment and aiming toward an explosive device threat. The invention enables a disrupter to be quickly and accurately set up, aligned, and aimed in order to render safe or to disrupt a target from a standoff position.

  17. Objectively measured physical activity and sedentary time: cross-sectional and prospective associations with adiposity in the Millennium Cohort Study

    PubMed Central

    Griffiths, Lucy J; Sera, Francesco; Cortina-Borja, Mario; Law, Catherine; Ness, Andrew; Dezateux, Carol

    2016-01-01

    Objective To examine whether physical activity (PA) and sedentary time (ST) in primary school-aged children are associated with adiposity at the start of secondary school, and whether these associations differ by sex or ethnic group. Design Nationally representative prospective cohort study. Setting Children born across the UK, between 2000 and 2002. Participants 6497 singleton children. Outcome measures Measures of adiposity (body mass index (BMI), fat mass index (FMI) and fat free mass index (FFMI))—obtained at 7 and 11 years. Explanatory measures Total daily PA (mean counts per minute (cpm)); minutes of moderate-to-vigorous PA (MVPA); and ST. All assessed at 7 years using accelerometers. Results In cross-sectional analyses, total PA was inversely associated with FMI (3.7% (95% CI 2.7% to 4.7%) reduction per 150 cpm increase), as was MVPA (4.2% (CI 3.2% to 5.2%) reduction per 20 min/day increase). Associations were stronger in black and South Asian ethnic groups. Total PA and MVPA were not associated with FFMI. ST was positively associated with FMI (1.3% (CI 0.2% to 2.3%) increase per 50 min/day increase) and inversely associated with FFMI (0.5% (CI 0.2% to 0.7%) reduction per 50 min/day increase). Longitudinally, MVPA at age 7 years remained inversely associated with FMI at age 11 years (1.5% (CI 0.4% to 2.6%) reduction per 20 min/day increase). No association was found between total PA and ST and any of the later adiposity measures. Conclusions 7-year-old children who are more physically active are less likely to be obese at that age and at age 11 years. These associations were particularly evident in children from black or South Asian ethnicity at age 7 years and in boys at age 11 years. Measurements of fat mass provide valuable insights into ethnic differences in associations between adiposity and activity. PMID:27067891

  18. The airborne mass spectrometer AIMS - Part 2: Measurements of trace gases with stratospheric or tropospheric origin in the UTLS

    NASA Astrophysics Data System (ADS)

    Jurkat, Tina; Kaufmann, Stefan; Voigt, Christiane; Schäuble, Dominik; Jeßberger, Philipp; Ziereis, Helmut

    2016-04-01

    Understanding the role of climate-sensitive trace gas variabilities in the upper troposphere and lower stratosphere region (UTLS) and their impact on its radiative budget requires accurate measurements. The composition of the UTLS is governed by transport and chemistry of stratospheric and tropospheric constituents, such as chlorine, nitrogen oxide and sulfur compounds. The Atmospheric chemical Ionization Mass Spectrometer AIMS has been developed to accurately measure a set of these constituents on aircraft by means of chemical ionization. Here we present a setup using SF5- reagent ions for the simultaneous measurement of trace gas concentrations of HCl, HNO3 and SO2 in the pptv to ppmv (10-12 to 10-6 mol mol-1) range with in-flight and online calibration called AIMS-TG (Atmospheric chemical Ionization Mass Spectrometer for measurements of trace gases). Part 1 of this paper (Kaufmann et al., 2016) reports on the UTLS water vapor measurements with the AIMS-H2O configuration. The instrument can be flexibly switched between two configurations depending on the scientific objective of the mission. For AIMS-TG, a custom-made gas discharge ion source has been developed for generation of reagent ions that selectively react with HCl, HNO3, SO2 and HONO. HNO3 and HCl are routinely calibrated in-flight using permeation devices; SO2 is continuously calibrated during flight adding an isotopically labeled 34SO2 standard. In addition, we report on trace gas measurements of HONO, which is sensitive to the reaction with SF5-. The detection limit for the various trace gases is in the low 10 pptv range at a 1 s time resolution with an overall uncertainty of the measurement of the order of 20 %. AIMS has been integrated and successfully operated on the DLR research aircraft Falcon and HALO (High Altitude LOng range research aircraft). As an example, measurements conducted during the TACTS/ESMVal (Transport and Composition of the LMS/UT and Earth System Model Validation) mission with

  19. THE AIMS AND ACTIVITIES OF THE INTERNATIONAL NETWORK OF NUCLEAR STRUCTURE AND DECAY DATA EVALUATORS.

    SciTech Connect

    NICHOLS,A.L.; TULI, J.K.

    2007-04-22

    International Network of Nuclear Structure and Decay Data (NSDD) Evaluators consists of a number of evaluation groups and data service centers in several countries that appreciate the merits of working together to maintain and ensure the quality and comprehensive content of the ENSDF database (Evaluated Nuclear Structure Data File). Biennial meetings of the network are held under the auspices of the International Atomic Energy Agency (IAEA) to assign evaluation responsibilities, monitor progress, discuss improvements and emerging difficulties, and agree on actions to be undertaken by individual members. The evaluated data and bibliographic details are made available to users via various media, such as the journals ''Nuclear Physics A'' and ''Nuclear Data Sheets'', the World Wide Web, on CD-ROM, wall charts of the nuclides and ''Nuclear Wallet Cards''. While the ENSDF master database is maintained by the US National Nuclear Data Center at the Brookhaven National Laboratory, these data are also available from other nuclear data centers including the IAEA Nuclear Data Section. The Abdus Salam International Centre for Theoretical Physics (ICTP), Trieste, Italy, in cooperation with the IAEA, organizes workshops on NSDD at regular intervals. The primary aims of these particular workshops are to provide hands-on training in the data evaluation processes, and to encourage new evaluators to participate in NSDD activities. The technical contents of these NSDD workshops are described, along with the rationale for the inclusion of various topics.

  20. The airborne mass spectrometer AIMS - Part 2: Measurements of trace gases with stratospheric or tropospheric origin in the UTLS

    NASA Astrophysics Data System (ADS)

    Jurkat, T.; Kaufmann, S.; Voigt, C.; Schäuble, D.; Jeßberger, P.; Ziereis, H.

    2015-12-01

    Understanding the role of climate-sensitive trace gas variabilities in the upper troposphere and lower stratosphere region (UTLS) and their impact on its radiative budget requires accurate measurements. The composition of the UTLS is governed by transport and chemistry of stratospheric and tropospheric constituents, such as chlorine, nitrogen oxide and sulphur components. The Airborne chemical Ionization Mass Spectrometer AIMS has been developed to accurately measure a set of these constituents on aircraft by means of chemical ionization. Here we present a setup using chemical ionization with SF5- reagent ions for the simultaneous measurement of trace gas concentrations in the pptv to ppmv (10-12 to 10-6 mol mol-1) range of HCl, HNO3 and SO2 with in-flight and online calibration called AIMS-TG. Part 1 of this paper (Kaufmann et al., 2015) reports on the UTLS water vapour measurements with the AIMS-H2O configuration. The instrument can be flexibly switched between two configurations depending on the scientific objective of the mission. For AIMS-TG, a custom-made gas discharge ion source has been developed generating a characteristic ionization scheme. HNO3 and HCl are routinely calibrated in-flight using permeation devices, SO2 is permanently calibrated during flight adding an isotopically labelled 34SO2 standard. In addition, we report on trace gas measurements of HONO which is sensitive to the reaction with SF5-. The detection limit for the various trace gases is in the low ten pptv range at a 1 s time resolution with an overall uncertainty of the measurement in the order of 20 %. AIMS has been integrated and successfully operated on the DLR research aircraft Falcon and HALO. Exemplarily, measurements conducted during the TACTS/ESMVal mission with HALO in 2012 are presented, focusing on a classification of tropospheric and stratospheric influences in the UTLS region. Comparison of AIMS measurements with other measurement techniques allow to draw a comprehensive

  1. Assessing the quality of rainfall data when aiming to achieve flood resilience

    NASA Astrophysics Data System (ADS)

    Hoang, C. T.; Tchiguirinskaia, I.; Schertzer, D.; Lovejoy, S.

    2012-04-01

    A new EU Floods Directive entered into force five years ago. This Directive requires Member States to coordinate adequate measures to reduce flood risk. European flood management systems require reliable rainfall statistics, e.g. the Intensity-duration-Frequency curves for shorter and shorter durations and for a larger and larger range of return periods. Preliminary studies showed that the number of floods was lower when using low time resolution data of high intensity rainfall events, compared to estimates obtained with the help of higher time resolution data. These facts suggest that a particular attention should be paid to the rainfall data quality in order to adequately investigate flood risk aiming to achieve flood resilience. The potential consequences of changes in measuring and recording techniques have been somewhat discussed in the literature with respect to a possible introduction of artificial inhomogeneities in time series. In this paper, we discuss how to detect another artificiality: most of the rainfall time series have a lower recording frequency than that is assumed, furthermore the effective high-frequency limit often depends on the recording year due to algorithm changes. This question is particularly important for operational hydrology, because an error on the effective recording high frequency introduces biases in the corresponding statistics. In this direction, we developed a first version of a SERQUAL procedure to automatically detect the effective time resolution of highly mixed data. Being applied to the 166 rainfall time series in France, the SERQUAL procedure has detected that most of them have an effective hourly resolution, rather than a 5 minutes resolution. Furthermore, series having an overall 5 minute resolution do not have it for all years. These results raise serious concerns on how to benchmark stochastic rainfall models at a sub-hourly resolution, which are particularly desirable for operational hydrology. Therefore, database

  2. The Sheep Survey: What Kind of Objects Make Up the X-Ray Background

    NASA Technical Reports Server (NTRS)

    Zezas, Andreas

    2004-01-01

    This program aims in the understanding of the objects which produce the hard X-ray back- ground. The SHEEP survey consists of objects observed in very hard X-rays in serendipitous ASCA pointings. A subset of this sample was observed with XMM-Newton in order to study their spectral properties.

  3. Distribution of the near-earth objects

    NASA Astrophysics Data System (ADS)

    Emel'Yanenko, V. V.; Naroenkov, S. A.; Shustov, B. M.

    2011-12-01

    This paper analyzes the distribution of the orbits of near-Earth minor bodies from the data on more than 7500 objects. The distribution of large near-Earth objects (NEOs) with absolute magnitudes of H < 18 is generally consistent with the earlier predictions (Bottke et al., 2002; Stuart, 2003), although we have revealed a previously undetected maximum in the distribution of perihelion distances q near q = 0.5 AU. The study of the orbital distribution for the entire sample of all detected objects has found new significant features. In particular, the distribution of perihelion longitudes seriously deviates from a homogeneous pattern; its variations are roughly 40% of its mean value. These deviations cannot be stochastic, which is confirmed by the Kolmogorov-Smirnov test with a more than 0.9999 probability. These features can be explained by the dynamic behavior of the minor bodies related to secular resonances with Jupiter. For the objects with H < 18, the variations in the perihelion longitude distribution are not so apparent. By extrapolating the orbital characteristics of the NEOs with H < 18, we have obtained longitudinal, latitudinal, and radial distributions of potentially hazardous objects in a heliocentric ecliptic coordinate frame. The differences in the orbital distributions of objects of different size appear not to be a consequence of observational selection, but could indicate different sources of the NEOs.

  4. Are changes in weather masking the efficacy of measures aimed at mitigating diffuse pollution?

    NASA Astrophysics Data System (ADS)

    Mellander, Per-Erik; Jordan, Phil; Shore, Mairead; McDonald, Noeleen; Shortle, Ger

    2016-04-01

    Interpretations of the efficacy of mitigation measures for reducing nitrogen (N) and phosphorus (P) losses from agricultural sources to water bodies are challenged by the temporal variability of air temperature and rainfall. Influences are different depending on flow controls, associated time lags and nutrient transformations that may occur along the pathways. In Europe weather patterns and trends are influenced by large-scale weather systems over the North Atlantic. One of the most prominent teleconnection patterns that affect the weather across all seasons is the North Atlantic Oscillation (NAO). In northwestern Europe a positive phase in the NAO index over the winter period is often associated with elevated air temperatures in summer and more frequent large rain events in winter than normal. The objective of this study was to investigate the catchment-scale influences and relationships of naturally altered hydro-meteorological processes on the diffuse N and P losses to waters, in order to distinguish natural climate effects from those caused by adaptive management (increased agricultural intensity, decreased nutrient use etc.). Here we present six years of monthly nitrate-N and total reactive P concentrations in stream water (aggregated from sub-hourly monitoring) in six, ca. 10 km2, Irish agricultural catchments with different hydrological flow controls and land use. The locations of the catchments make them susceptible to sudden and/or seasonal shifts in weather. Changes in long term air temperatures and rainfall were investigated and annual N and P concentrations were compared to the NAO. During the monitored period (2009-2015) there was a steady increase in wintertime NAO index, reaching positive values in recent years, resulting in higher air temperatures and more frequent large rain events in winter. In some settings annual N and/or P concentrations were positively correlated to the three-year moving average NAO index (R2 > 0.90). Catchments with free

  5. The study of control methods in opto-electronic tracking technology for fast object with horizontal gimbal

    NASA Astrophysics Data System (ADS)

    Li, Zhi-jun; Liu, Qiong; Mao, Yao

    2015-10-01

    It is inevitable that tracking high-elevation object exists blind region with horizontal gimbal, need to take some control methods to improve the system for high-elevation target tracking capability and reduce the blind region. This paper compares several common tracking control methods, including compound axis control of dual detector, compound axis control of single detector, compound axis control of single detector with modified guidance, analyzes the principle of operation, advantages and disadvantages, and validates by experiments. The experimental results showed that it is stable and reliable using guide modified compound axis control of single detector when the target position information is more accurate. On the other hand, it is able to meet the needs to track target with high speed and high acceleration using improved compound axis control of single detector when the target position information is not very accurate.

  6. Geriatrics and the triple aim: defining preventable hospitalizations in the long-term care population.

    PubMed

    Ouslander, Joseph G; Maslow, Katie

    2012-12-01

    Reducing preventable hospitalizations is fundamental to the "triple aim" of improving care, improving health, and reducing costs. New federal government initiatives that create strong pressure to reduce such hospitalizations are being or will soon be implemented. These initiatives use quality measures to define which hospitalizations are preventable. Reducing hospitalizations could greatly benefit frail and chronically ill adults and older people who receive long-term care (LTC) because they often experience negative effects of hospitalization, including hospital-acquired conditions, morbidity, and loss of functional abilities. Conversely, reducing hospitalizations could mean that some people will not receive hospital care they need, especially if the selected measures do not adequately define hospitalizations that can be prevented without jeopardizing the person's health and safety. An extensive literature search identified 250 measures of preventable hospitalizations, but the measures have not been validated in the LTC population and generally do not account for comorbidity or the capacity of various LTC settings to provide the required care without hospitalization. Additional efforts are needed to develop measures that accurately differentiate preventable from necessary hospitalizations for the LTC population, are transparent and fair to providers, and minimize the potential for gaming and unintended consequences. As the new initiatives take effect, it is critical to monitor their effect and to develop and disseminate training and resources to support the many community- and institution-based healthcare professionals and emergency department staff involved in decisions about hospitalization for this population. PMID:23194066

  7. Pouring or chilling a bottle of wine: an fMRI study on the prospective planning of object-directed actions.

    PubMed

    van Elk, M; Viswanathan, S; van Schie, H T; Bekkering, H; Grafton, S T

    2012-04-01

    This fMRI study investigates the neural mechanisms supporting the retrieval of action semantics. A novel motor imagery task was used in which participants were required to imagine planning actions with a familiar object (e.g. a toothbrush) or with an unfamiliar object (e.g. a pair of pliers) based on either goal-related information (i.e. where to move the object) or grip-related information (i.e. how to grasp the object). Planning actions with unfamiliar compared to familiar objects was slower and was associated with increased activation in the bilateral superior parietal lobe, the right inferior parietal lobe and the right insula. The stronger activation in parietal areas for unfamiliar objects fits well with the idea that parietal areas are involved in motor imagery and suggests that this process takes more effort in the case of novel or unfamiliar actions. In contrast, the planning of familiar actions resulted in increased activation in the anterior prefrontal cortex, suggesting that subjects maintained a stronger goal-representation when planning actions with familiar compared to unfamiliar objects. These findings provide further insight into the neural structures that support action semantic knowledge for the functional use of real-world objects and suggest that action semantic knowledge is activated most readily when actions are planned in a goal-directed manner. PMID:22349497

  8. JEM-EUSO mission on the ISS with the aim of performing particle astronomy

    NASA Astrophysics Data System (ADS)

    Inoue, N.; Miyazawa, K.; Kawasaki, Y.; JEM-EUSO Collaboration

    2009-12-01

    The Extreme Universe Space Observatory (EUSO) is a science mission to investigate the nature and origin of Extremely-High-Energy Cosmic Rays (EHECRs) with primary energy(E0) >7×1019eV. It will be installed in the Japanese Experiment Module (JEM) on the International Space Station (ISS). This mission is aimed to perform charged-particle astronomy in this energy region with large statistics of EHECRs (>1000 events above 7×1019eV) in 5 years observation. The JEM-EUSO telescope has a Field of View(FoV) of 60°×48° and a cumulative exposure of >4×105km2ṡsrṡyr. It consists of high-transmittance Fresnel lenses (a side-cut shape with a 2.65 m major axis), a cluster of multi-anode photomultipliers(MAPMT) as a photo-sensitive detector at the focal surface and suitable electronics. JEM-EUSO has been selected as one of the mission candidates of the second phase utilization of JEM expected in early 2010s, by the Japan Aerospace eXploration Agency(JAXA).

  9. JEM-EUSO mission on the ISS with the aim of performing particle astronomy

    NASA Astrophysics Data System (ADS)

    Inoue, N.; Miyazawa, K.; Kawasaki, Y.; JEM-EUSO Collaboration

    2009-12-01

    The Extreme Universe Space Observatory (EUSO) is a science mission to investigate the nature and origin of Extremely-High-Energy Cosmic Rays (EHECRs) with primary energy(E 0) >7×10eV. It will be installed in the Japanese Experiment Module (JEM) on the International Space Station (ISS). This mission is aimed to perform charged-particle astronomy in this energy region with large statistics of EHECRs (>1000 events above 7×10eV) in 5 years observation. The JEM-EUSO telescope has a Field of View(FoV) of 60×48 and a cumulative exposure of >4×10kmṡsrṡyr. It consists of high-transmittance Fresnel lenses (a side-cut shape with a 2.65 m major axis), a cluster of multi-anode photomultipliers(MAPMT) as a photo-sensitive detector at the focal surface and suitable electronics. JEM-EUSO has been selected as one of the mission candidates of the second phase utilization of JEM expected in early 2010s, by the Japan Aerospace eXploration Agency(JAXA).

  10. The History and Aim of LADY CATS —Simple and Beautiful Experiments

    NASA Astrophysics Data System (ADS)

    Tanemura, Masako; Okiharu, Fumiko; Yokoe, Mika; Taniguchi, Masa-aki; Maeda, Hiroaki; Kutome, Yuusuke; Kawakatsu, Hiroshi

    LADY CATS (LADY Creators of Activities for Teaching Science) is an organization of science teachers. Our group includes a lot of female teachers. We have demonstrated "Simple and beautiful experiments" since ICPE 2005. We aim to encourage both students and teachers who are not interested in physics. Our concepts of experiments are as follows: the "simple" experiments which the teachers in the world can utilize in their classes easily, the "beautiful" experiments in which children get interested, and the "essential" experiments which can demonstrate the principles of physics. We demonstrate several educational experiments of our group.

  11. New Mexico Look for the STARS--AIM HIGH: QRS Profile. The Child Care Quality Rating System (QRS) Assessment

    ERIC Educational Resources Information Center

    Child Trends, 2010

    2010-01-01

    This paper presents a profile of New Mexico's Look for the STARS--AIM HIGH prepared as part of the Child Care Quality Rating System (QRS) Assessment Study. The profile consists of several sections and their corresponding descriptions including: (1) Program Information; (2) Rating Details; (3) Quality Indicators for Center-Based Programs; (4)…

  12. The Automated Instrumentation and Monitoring System (AIMS): Design and Architecture. 3.2

    NASA Technical Reports Server (NTRS)

    Yan, Jerry C.; Schmidt, Melisa; Schulbach, Cathy; Bailey, David (Technical Monitor)

    1997-01-01

    Whether a researcher is designing the 'next parallel programming paradigm', another 'scalable multiprocessor' or investigating resource allocation algorithms for multiprocessors, a facility that enables parallel program execution to be captured and displayed is invaluable. Careful analysis of such information can help computer and software architects to capture, and therefore, exploit behavioral variations among/within various parallel programs to take advantage of specific hardware characteristics. A software tool-set that facilitates performance evaluation of parallel applications on multiprocessors has been put together at NASA Ames Research Center under the sponsorship of NASA's High Performance Computing and Communications Program over the past five years. The Automated Instrumentation and Monitoring Systematic has three major software components: a source code instrumentor which automatically inserts active event recorders into program source code before compilation; a run-time performance monitoring library which collects performance data; and a visualization tool-set which reconstructs program execution based on the data collected. Besides being used as a prototype for developing new techniques for instrumenting, monitoring and presenting parallel program execution, AIMS is also being incorporated into the run-time environments of various hardware testbeds to evaluate their impact on user productivity. Currently, the execution of FORTRAN and C programs on the Intel Paragon and PALM workstations can be automatically instrumented and monitored. Performance data thus collected can be displayed graphically on various workstations. The process of performance tuning with AIMS will be illustrated using various NAB Parallel Benchmarks. This report includes a description of the internal architecture of AIMS and a listing of the source code.

  13. [The late-life companion and the inanimate object of the person with senile dementia: an attempt at comprehension through a comparative study with phenomena encountered during childhood].

    PubMed

    Léger, J M; Garoux, R; Tessier, J F; Chevalier, B

    1986-04-01

    The thought of this work about the mad senile person's affective life concerns some almost permanent clinical establishments such as: on one hand, the existence of late-life companions and inanimate objects evoking some phenomena met during childhood: fancied companion, fetish objects. On the other hand, the existence of "behaviours" evoking those of the little child during his psycho-affective development. We have been led to study the notion of regression during the dementia process and ask ourselves about psychopathological mechanisms underlying this regression, regarded as a mechanism of narcissistic strengthening underlying the appearance of late-life companion or inanimate object. We underline in the conclusion that: on one hand, for these persons showing a deep disturbance of narcissistic economy, there is need to elaborate a relation with a narcissistic object, according to the somato-psychic deterioration level. On the other hand, the phenomena established during the dementia process, can't be assimilated to opposite distance covered by progressive movement. PMID:3813329

  14. The Advanced Industrial Materials (AIM) program office of industrial technologies fiscal year 1995

    SciTech Connect

    Sorrell, C.A.

    1997-04-01

    In many ways, the Advanced Industrial Materials (AIM) Program underwent a major transformation in FY95 and these changes have continued to the present. When the Program was established in 1990 as the Advanced Industrial Concepts (AIC) Materials Program, the mission was to conduct applied research and development to bring materials and processing technologies from the knowledge derived from basic research to the maturity required for the end use sectors for commercialization. In 1995, the Office of Industrial Technologies (OIT) made radical changes in structure and procedures. All technology development was directed toward the seven `Vision Industries` that use about 80% of industrial energy and generated about 90% of industrial wastes. These are: aluminium; chemical; forest products; glass; metal casting; refineries; and steel. OIT is working with these industries, through appropriate organizations, to develop Visions of the desired condition of each industry some 20 to 25 years in the future and then to prepare Road Maps and Implementation Plans to enable them to reach their goals. The mission of AIM has, therefore, changed to `Support development and commercialization of new or improved materials to improve productivity, product quality, and energy efficiency in the major process industries.`

  15. Hydrogen Economy: The Role of Nano-scaled Support Material for Electrocatalysts Aimed for Water Electrolysis

    NASA Astrophysics Data System (ADS)

    Paunović, Perica; Popovski, Orce; Dimitrov, Aleksandar T.

    The role and importance of support materials for electrocatalysts aimed for water electrolysis is given. Besides their superior support characteristics such as electroconductivity, a high developed surface area and chemical stability, support materials should be an active participant in the catalytic activity through strong metal-support interactions (SMSI) with the metallic catalytic phase. Subject of this paper are several support materials: (i) Vulcan XC-72, (ii) Vulcan XC-72 with TiO2, (iii) multiwalled carbon nanotubes (MWCNTs) and (iv) Magneli phases, i.e. nonstoichiometric titanium oxides. A comparison of catalytic activity of Co-based electrocatalysts deposited on all support materials mentioned is given.

  16. The influence of the dorsolateral prefrontal cortex on attentional behavior and decision making. A t-DCS study on emotionally vs. functionally designed objects.

    PubMed

    Colombo, Barbara; Balzarotti, Stefania; Mazzucchelli, Nicla

    2016-04-01

    Prior research has shown that right dorsolateral prefrontal cortex may be crucial in cognitive control of affective impulses during decision making. The present study examines whether modulation of r-DLPFC with transcranial direct current stimulation influences attentional behavior and decision-making in a purchase task requiring participants to choose either emotional/attractive or functional/useful objects. 30 participants were shown sixteen pairs of emotionally or functionally designed products while their eye-movements were recorded. Participants were asked to judge aesthetics and usefulness of each object, and to decide which object of each pair they would buy. Results revealed that participants decided to buy the functionally designed objects more often regardless of condition; however, participants receiving anodal stimulation were faster in decision making. Although stimulation of r-DLPFC did not affect the actual purchasing choice and had little effect on visual exploration during decision making, it influenced perceived usefulness and attractiveness, with temporary inhibition of r-DLPFC leading to evaluate functional objects as less attractive. Finally, anodal stimulation led to judge the objects as more useful. The implications of these results are discussed. PMID:26859525

  17. Informatics in radiology: automated structured reporting of imaging findings using the AIM standard and XML.

    PubMed

    Zimmerman, Stefan L; Kim, Woojin; Boonn, William W

    2011-01-01

    Quantitative and descriptive imaging data are a vital component of the radiology report and are frequently of paramount importance to the ordering physician. Unfortunately, current methods of recording these data in the report are both inefficient and error prone. In addition, the free-text, unstructured format of a radiology report makes aggregate analysis of data from multiple reports difficult or even impossible without manual intervention. A structured reporting work flow has been developed that allows quantitative data created at an advanced imaging workstation to be seamlessly integrated into the radiology report with minimal radiologist intervention. As an intermediary step between the workstation and the reporting software, quantitative and descriptive data are converted into an extensible markup language (XML) file in a standardized format specified by the Annotation and Image Markup (AIM) project of the National Institutes of Health Cancer Biomedical Informatics Grid. The AIM standard was created to allow image annotation data to be stored in a uniform machine-readable format. These XML files containing imaging data can also be stored on a local database for data mining and analysis. This structured work flow solution has the potential to improve radiologist efficiency, reduce errors, and facilitate storage of quantitative and descriptive imaging data for research. PMID:21357413

  18. Clearly Communicating the Learning Objective Matters!

    ERIC Educational Resources Information Center

    Reed, Deborah K.

    2012-01-01

    Explicitly communicating objectives is a tenet of effective instruction for students with learning difficulties, yet the practice is often overlooked in research. This case study of a novice middle school geography teacher illustrates how the qualitative and quantitative differences in the ways a teacher communicates the learner expectation can…

  19. Motor Inhibition Affects the Speed But Not Accuracy of Aimed Limb Movements in an Insect

    PubMed Central

    Calas-List, Delphine; Clare, Anthony J.; Komissarova, Alexandra; Nielsen, Thomas A.

    2014-01-01

    When reaching toward a target, human subjects use slower movements to achieve higher accuracy, and this can be accompanied by increased limb impedance (stiffness, viscosity) that stabilizes movements against motor noise and external perturbation. In arthropods, the activity of common inhibitory motor neurons influences limb impedance, so we hypothesized that this might provide a mechanism for speed and accuracy control of aimed movements in insects. We recorded simultaneously from excitatory leg motor neurons and from an identified common inhibitory motor neuron (CI1) in locusts that performed natural aimed scratching movements. We related limb movement kinematics to recorded motor activity and demonstrate that imposed alterations in the activity of CI1 influenced these kinematics. We manipulated the activity of CI1 by injecting depolarizing or hyperpolarizing current or killing the cell using laser photoablation. Naturally higher levels of inhibitory activity accompanied faster movements. Experimentally biasing the firing rate downward, or stopping firing completely, led to slower movements mediated by changes at several joints of the limb. Despite this, we found no effect on overall movement accuracy. We conclude that inhibitory modulation of joint stiffness has effects across most of the working range of the insect limb, with a pronounced effect on the overall velocity of natural movements independent of their accuracy. Passive joint forces that are greatest at extreme joint angles may enhance accuracy and are not affected by motor inhibition. PMID:24872556

  20. Multi-wavelength study of flaring activity in BL Lac object S5 0716+714 during the 2015 outburst

    SciTech Connect

    Chandra, Sunil; Zhang, Haocheng; Kushwaha, Pankaj; Singh, K. P.; Bottcher, M.; Kaur, Navpreet; Baliyan, K. S.

    2015-08-17

    We present a detailed investigation of the flaring activity observed from a BL Lac object, S5 0716+714 , during its brightest ever optical state in the second half of 2015 January. Observed almost simultaneously in the optical, X-rays, and γ-rays, a significant change in the degree of optical polarization (PD) and a swing in the position angle (PA) of polarization were recorded. A TeV (VHE) detection was also reported by the MAGIC consortium during this flaring episode. Two prominent sub-flares, peaking about five days apart, were seen in almost all of the energy bands. The multi-wavelength light curves, spectral energy distribution, and polarization are modeled using the time-dependent code developed by Zhang et al. This model assumes a straight jet threaded by large-scale helical magnetic fields taking into account the light travel time effects, incorporating synchrotron flux and polarization in 3D geometry. Furthermore, the rapid variation in PD and rotation in PA are most likely due to reconnections happening in the emission region in the jet, as suggested by the change in the ratio of toroidal to poloidal components of the magnetic field during the quiescent and flaring states.

  1. Multi-wavelength study of flaring activity in BL Lac object S5 0716+714 during the 2015 outburst

    DOE PAGESBeta

    Chandra, Sunil; Zhang, Haocheng; Kushwaha, Pankaj; Singh, K. P.; Bottcher, M.; Kaur, Navpreet; Baliyan, K. S.

    2015-08-17

    We present a detailed investigation of the flaring activity observed from a BL Lac object, S5 0716+714 , during its brightest ever optical state in the second half of 2015 January. Observed almost simultaneously in the optical, X-rays, and γ-rays, a significant change in the degree of optical polarization (PD) and a swing in the position angle (PA) of polarization were recorded. A TeV (VHE) detection was also reported by the MAGIC consortium during this flaring episode. Two prominent sub-flares, peaking about five days apart, were seen in almost all of the energy bands. The multi-wavelength light curves, spectral energymore » distribution, and polarization are modeled using the time-dependent code developed by Zhang et al. This model assumes a straight jet threaded by large-scale helical magnetic fields taking into account the light travel time effects, incorporating synchrotron flux and polarization in 3D geometry. Furthermore, the rapid variation in PD and rotation in PA are most likely due to reconnections happening in the emission region in the jet, as suggested by the change in the ratio of toroidal to poloidal components of the magnetic field during the quiescent and flaring states.« less

  2. Multi-wavelength Study of Flaring Activity in BL Lac Object S5 0716+714 during the 2015 Outburst

    NASA Astrophysics Data System (ADS)

    Chandra, Sunil; Zhang, Haocheng; Kushwaha, Pankaj; Singh, K. P.; Bottcher, M.; Kaur, Navpreet; Baliyan, K. S.

    2015-08-01

    We present a detailed investigation of the flaring activity observed from a BL Lac object, S5 0716+714 , during its brightest ever optical state in the second half of 2015 January. Observed almost simultaneously in the optical, X-rays, and γ-rays, a significant change in the degree of optical polarization (PD) and a swing in the position angle (PA) of polarization were recorded. A TeV (VHE) detection was also reported by the MAGIC consortium during this flaring episode. Two prominent sub-flares, peaking about five days apart, were seen in almost all of the energy bands. The multi-wavelength light curves, spectral energy distribution, and polarization are modeled using the time-dependent code developed by Zhang et al. This model assumes a straight jet threaded by large-scale helical magnetic fields taking into account the light travel time effects, incorporating synchrotron flux and polarization in 3D geometry. The rapid variation in PD and rotation in PA are most likely due to reconnections happening in the emission region in the jet, as suggested by the change in the ratio of toroidal to poloidal components of the magnetic field during the quiescent and flaring states.

  3. Spray aiming in bombardier beetles: jet deflection by the coanda effect.

    PubMed

    Eisner, T; Aneshansley, D J

    1982-01-01

    Bombardier beetles of the carabid subfamily Paussinae have a pair of flanges, diagnostic for the group, that project outward from the sides of the body. Behind each flange is a gland opening, from which the beetles discharge a hot, quinone-containing secretion when disturbed. The flanges are curved and grooved and serve as launching guides for anteriorly aimed ejections of secretion. Jets of fluid, on emergence from the gland openings, follow the curvature of the flanges and are thereby bent sharply in their trajectory and directed forward. The phenomenon is illustrative of the Coanda effect, widely applicable in engineering and responsible for the familiar tendency of liquids to curve around spouts and down the front of containers when being poured. PMID:17790472

  4. The Objectives of the Egyptian Space Programme

    NASA Astrophysics Data System (ADS)

    Shaltout, Mosalam

    : The aim of the Egyptsat series is to build on the experience gained from these missions to extend Egypt's space effort into scientific research and to expand its role in educational, agricultural and other development fields. The Egyptian Space Programme envisages that Egypt will be able to join the space age through the gradual establishment of the facilities needed for the manufacture of small research and remote sensing satellites, by acquiring appropriate technological knowledge and capabilities, and by building up the necessary infrastructure to enable the country to design and manufacture its own small satellites. Included in this overall vision would be the capacity to utilize space technologies And applications to serve the national development plans and contribute to the development of scientific and technological research in Egypt, as well as to the establishment of a scientific and research base for advanced industries in Egypt. To hasten the achievement of some or all of these objectives, it will be necessary to: • Transfer advanced space technologies in communication, computers, programs, optics, sensors, new materials, command and control, and energy into the domain of the Egyptian scientific community. • Utilize space technologies and apply these to the country's development plans. • Acquire national capabilities in space technology disciplines. Establish scientific and industrial base in advanced technology fields. • Enhance our human resource capabilities for space sciences fields. • Promote cooperation between the country's research and industrial centres in order to bring about successful project within the national space programme.

  5. Individuation of Objects and Events: A Developmental Study

    ERIC Educational Resources Information Center

    Wagner, Laura; Carey, Susan

    2003-01-01

    This study investigates children's ability to use language to guide their choice of individuation criterion in the domains of objects and events. Previous work (Shipley, E. F., & Shepperson, B. (1990). Countable entities: developmental changes. "Cognition," 34, 109-136.) has shown that children have a strong bias to use a spatio-temporal…

  6. AIM Spacecraft Instruments

    NASA Video Gallery

    AIM will make simultaneous measurements of the main ingredients needed to form these clouds and will unravel the role of natural factors, such as the solar cycle and meteorology, from the possible ...

  7. Aim, Load, Fire: The Type VI Secretion System, a Bacterial Nanoweapon.

    PubMed

    Cianfanelli, Francesca R; Monlezun, Laura; Coulthurst, Sarah J

    2016-01-01

    Bacteria utilise specialised protein secretion systems to interact with host organisms, competitor bacteria, and the environment. The Type VI secretion system (T6SS) is a versatile weapon deployed by many bacterial species to target either host cells or rival bacteria. The widespread occurrence and significance of the T6SS is becoming increasingly appreciated, as is its intriguing mode of action. The T6SS delivers multiple, diverse effector proteins directly into target cells using a dynamic 'firing' mechanism related to the action of contractile bacteriophage tails. Here, we summarise the contribution of recent findings to our developing picture of how the T6SS assembles and fires, how it is loaded with different types of effectors, and how it can be aimed towards an incoming assault. PMID:26549582

  8. Cardiothoracic surgery training in Israel: A critical look at the past, aiming for a better future.

    PubMed

    Shapira, Oz M; Sahar, Gideon; Raanani, Ehud

    2016-06-01

    Training the next generation of cardiothoracic surgeons is a global persistent challenge. Major issues, including length of training, decreasing volume of cases, shift toward high-risk, complex, and less-invasive procedures, increased specialization, and uncertainty with regard to future employment, are relevant and affect residency training programs in the United States, Europe, and other parts of the world. To produce high-quality, mature, and qualified surgeons, these challenges mandate an ongoing effort by our specialty leadership aimed at identifying creative solutions and adapting the current residency training curricula and methodology to the dynamic changes in our field. The current situation in Israel is discussed with the hope that sharing our experience might be useful and lead to adoption of some of our solutions by other countries. PMID:26874603

  9. Geographic health information systems: a platform to support the 'triple aim'.

    PubMed

    Miranda, Marie Lynn; Ferranti, Jeffrey; Strauss, Benjamin; Neelon, Brian; Califf, Robert M

    2013-09-01

    Despite the rapid growth of electronic health data, most data systems do not connect individual patient records to data sets from outside the health care delivery system. These isolated data systems cannot support efforts to recognize or address how the physical and environmental context of each patient influences health choices and health outcomes. In this article we describe how a geographic health information system in Durham, North Carolina, links health system and social and environmental data via shared geography to provide a multidimensional understanding of individual and community health status and vulnerabilities. Geographic health information systems can be useful in supporting the Institute for Healthcare Improvement's Triple Aim Initiative to improve the experience of care, improve the health of populations, and reduce per capita costs of health care. A geographic health information system can also provide a comprehensive information base for community health assessment and intervention for accountable care that includes the entire population of a geographic area. PMID:24019366

  10. Dictionaries and "That" Dictionary: A Casebook on the Aims of Lexicographers and the Targets of Reviewers.

    ERIC Educational Resources Information Center

    Sledd, James; Ebbitt, Wilma R.

    Part 1 of this casebook on dictionary study contains articles written over the last 200 years by seven eminent lexicographers, including Samuel Johnson and Noah Webster, on the history, nature, and purposes of the English dictionary. Part 2 contains 62 chronologically arranged readings published between September, 1961, and May, 1962, on…

  11. Searching for and Studying Primitive Solar System Objects

    NASA Astrophysics Data System (ADS)

    Chen, Jun

    1997-08-01

    Jovian Trojans, 'Trojans' of Saturn, Uranus and Neptune (Lagrangian objects, in the language of this dissertation), Kuiper Belt objects (KBOs) and Centaurs are believed to be the pristine bodies in the solar system. This thesis project describes a search for, and investigation of, these primitive objects using state-of-the-art charge-coupled device (CCD) cameras. With a CCD, 93 Jovian L4 Trojans with sizes ranging from ~4 km to 40 km diameter were discovered. The cumulative magnitude-frequency distribution is found to have slope of 0.397 ± 0.008 and the bias corrected mean inclination is 13o.7 ± 0o.5. The total number of the L4 Trojans, the size and total mass of the L4 cloud are discussed. My study shows that the previously suggested leakage rate of Trojans may be overestimated and that Trojans can not be a significant source of short period comets. No Lagrangian objects were discovered in this project. Instead, the 99% confidence level (~3/ σ) upper limits to their surface densities are given. Larger sky needs to be covered before the existence of such objects can be concluded. Nevertheless, the current survey shows that the surface density of Saturnian 'Trojans' is lower than that of Jovian Trojans. In addition, 16 published and 12 yet to be published KBOs were discovered in this project, as well as one Centaur. The dynamical properties of 42 published KBOs and 7 Centaurs are studied and their photometric properties are discussed. Our study shows that there is no discrepancy between the numbers of discovered Centaurs and those of KBOs as some suggested.

  12. A Study of Parameters of the Counterpropagating Leader and its Influence on the Lightning Protection of Objects Using Large-Scale Laboratory Modeling

    NASA Astrophysics Data System (ADS)

    Syssoev, V. S.; Kostinskiy, A. Yu.; Makalskiy, L. M.; Rakov, A. V.; Andreev, M. G.; Bulatov, M. U.; Sukharevsky, D. I.; Naumova, M. U.

    2014-04-01

    In this work, the results of experiments on initiating the upward and descending leaders during the development of a long spark when studying lightning protection of objects with the help of large-scale models are shown. The influence of the counterpropagating leaders on the process of the lightning strike of ground-based and insulated objects is discussed. In the first case, the upward negative leader is initiated by the positive downward leader, which propagates from the high-voltage electrode of the "rod-rod"-type Marx generator (the rod is located on the plane and is 3-m high) in the gap with a length of 9-12 m. The positive-voltage pulse with a duration of 7500 μs had an amplitude of up to 3 MV. In the second case, initiation of the positive upward leader was performed in the electric field created by a cloud of negatively charged aerosol, which simulates the charged thunderstorm cell. In this case, all the phases characteristic of the ascending lightnings initiated by the tall ground-based objects and the triggered lightnings during the experiments with an actual thunderstorm cloud were observed in the forming spark discharge with a length of 1.5-2.0 m. The main parameters of the counterpropagating leader, which is initiated by the objects during the large-scale model experiments with a long spark, are shown.

  13. Planning and setting objectives in field studies: Chapter 2

    USGS Publications Warehouse

    Fisher, Robert N.

    2016-01-01

    This chapter enumerates the steps required in designing and planning field studies on the ecology and conservation of reptiles, as these involve a high level of uncertainty and risk. To this end, the chapter differentiates between goals (descriptions of what one intends to accomplish) and objectives (the measurable steps required to achieve the established goals). Thus, meeting a specific goal may require many objectives. It may not be possible to define some of them until certain experiments have been conducted; often evaluations of sampling protocols are needed to increase certainty in the biological results. And if sampling locations are fixed and sampling events are repeated over time, then both study-specific covariates and sampling-specific covariates should exist. Additionally, other critical design considerations for field study include obtaining permits, as well as researching ethics and biosecurity issues.

  14. 78 FR 52933 - Strengthening the Operating Framework and Furthering the Objectives of Coalition for Accelerating...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-27

    ... Objectives of Coalition for Accelerating Standards and Therapies Initiative (U24) AGENCY: Food and Drug... Objectives The CFAST Initiative aims to accelerate clinical research and medical product development...

  15. The analyst's subjectivity and the analyst's objectivity.

    PubMed

    Renik, O

    1998-06-01

    The author suggests that, increasingly, contemporary psychoanalysts have been acknowledging and examining the intersubjectivity of the clinical encounter and that this trend has sometimes been misunderstood as necessitating the conclusion that objectivity is impossible to achieve in clinical psychoanalysis. In contrast to this, the author proposes a pragmatic definition of the analyst's objectivity that is entirely consistent with acceptance of the analyst's irreducible subjectivity, and illustrates his view by means of a clinical example. He suggests that objectivity concerns both objects and objectives, and indicates that a pragmatic conception of objectivity is employed throughout modern science. He explains why he regards psychoanalysis as a science, rather than as a hermeneutic discipline. He takes up the way in which implicit positivist assumptions can disadvantageously influence our thinking about the relation between an analyst's subjectivity and an analyst's objectivity. Finally, he discusses the important role of consensus in objectivity generally and in psychoanalytic objectivity particularly, as well as some of the differences that exist among analysts with regard to the specific objectives that take priority in clinical work. PMID:9717097

  16. A critical review of techniques aiming at enhancing and sustaining worker's alertness during the night shift.

    PubMed

    Bonnefond, Anne; Tassi, Patricia; Roge, Joceline; Muzet, Alain

    2004-01-01

    Two types of methods based on a particular principle allow enhancing and sustaining workers' alertness all along their night work. The first one rather consists in arousing workers by exposing them to stimulant environment conditions (light or noise...) or by giving them natural or pharmacological reactivating substances (caffeine or amphetamines...) for example. The second principle consists in increasing workers' possibilities for resting and allowing them to have short sleep periods or Short Rest Periods (SRP) in an adapted area at the workplace. In order to use these techniques in real work situations, after a critical review taking into account both efficiency, advantages and disadvantages but also applicability and acceptability, the SRP technique stands out as the most efficient method as it has a certain number of advantages with regard to our initial objective. PMID:14964612

  17. Treatment-Related Changes in Objectively Measured Parenting Behaviors in the Multimodal Treatment Study of Children with Attention-Deficit/Hyperactivity Disorder

    ERIC Educational Resources Information Center

    Wells, Karen C.; Chi, Terry C.; Hinshaw, Stephen P.; Epstein, Jeffery N.; Pfiffner, Linda; Nebel-Schwalm, Marie; Owens, Elizabeth B.; Arnold, L. Eugene; Abikoff, Howard B.; Conners, C. Keith; Elliott, Glen R.; Greenhill, Laurence L.; Hechtman, Lily; Hoza, Betsy; Jensen, Peter S.; March, John; Newcorn, Jeffrey H.; Pelham, William E.; Severe, Joanne B.; Swanson, James; Vitiello, Benedetto; Wigal, Timothy

    2006-01-01

    The present study examined treatment outcomes for objectively measured parenting behavior in the Multimodal Treatment Study of Children with Attention-Deficit/Hyperactivity Disorder (ADHD). Five hundred seventy-nine ethnically and socioeconomically diverse children with ADHD-combined type (ages 7.0-9.9 years) and their parent(s) were recruited …

  18. Epigallocatechin-3-gallate attenuates the AIM2-induced secretion of IL-1β in human epidermal keratinocytes.

    PubMed

    Yun, Mihee; Seo, Gimoon; Lee, Ji-Young; Chae, Gue Tae; Lee, Seong-Beom

    2015-11-27

    The pro-inflammatory cytokine interleukin-1β (IL-1β) plays a central role in the pathogenesis of psoriasis. Keratinocytes are a major source of IL-1β and express absent in melanoma 2 (AIM2). AIM2 recognizes a double-stranded DNA and initiates the IL-1β-processing of inflammasome. The AIM2 inflammasome is a cytosolic multiprotein complex composed of AIM2, an apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), and pro-caspase-1. Epigallocatechin-3-Gallate (EGCG), a major polyphenolic component of green tea, has anti-inflammatory properties. In the current study, we investigated the issue of whether or how EGCG suppresses AIM2 inflammasome in human epidermal keratinocytes, neonatal (HEKn). Treatment with EGCG, before or after IFN-γ priming, attenuated poly(dA:dT)-induced IL-1β secretion in HEKn cells. Pre-treatment with EGCG reduced the level of IFN-γ-induced priming signal via the down-regulation of pro-IL-1β and pro-capspase-1 in HEKn cells. Furthermore, treatment with EGCG attenuated poly(dA:dT)-induced ASC oligomerization and caspase-1 activation in IFN-γ-primed HEKn cells. These results suggest that EGCG attenuates AIM2-induced IL-1β secretion by suppressing both IFN-γ-mediated priming and poly(dA:dT)-induced ASC oligomerization of inflammasomes in human epidermal keratinocytes. PMID:26494301

  19. Exploring the relationship between object realism and object-based attention effects.

    PubMed

    Roque, Nelson; Boot, Walter R

    2015-09-01

    Visual attention prioritizes processing of locations in space, and evidence also suggests that the benefits of attention can be shaped by the presence of objects (object-based attention). However, the prevalence of object-based attention effects has been called into question recently by evidence from a large-sampled study employing classic attention paradigms (Pilz et al., 2012). We conducted two experiments to explore factors that might determine when and if object-based attention effects are observed, focusing on the degree to which the concreteness and realism of objects might contribute to these effects. We adapted the classic attention paradigm first reported by Egly, Driver, and Rafal (1994) by replacing abstract bar stimuli in some conditions with objects that were more concrete and familiar to participants: items of silverware. Furthermore, we varied the realism of these items of silverware, presenting either cartoon versions or photo-realistic versions. Contrary to predictions, increased realism did not increase the size of object-based effects. In fact, no clear object-based effects were observed in either experiment, consistent with previous failures to replicate these effects in similar paradigms. While object-based attention may exist, and may have important influences on how we parse the visual world, these and other findings suggest that the two-object paradigm typically relied upon to study object-based effects may not be the best paradigm to investigate these issues. PMID:26256694

  20. Radioastron: Main results of the implementation of the early science program in studies of astronomical objects in the universe with ultra-high angular resolution

    NASA Astrophysics Data System (ADS)

    Kardashev, N. S.; Alakoz, A. V.; Kovalev, Y. Y.; Popov, M. V.; Sobolev, A. M.; Sokolovsky, K. V.

    2015-12-01

    The paper presents the main results of the implementation of the Radioastron Early Science Program. Interferometric responses (fringes) were obtained for all types of studied radio sources (quasars, pulsars and cosmic masers) and in all ranges of wavelengths (from meter to centimeter range) with large spaceground baselines. Such measurements have provided a record angular resolution, in some cases reaching several tens of microseconds of arc. This brings unique scientific results concerning the nature of the processes occurring in the vicinity of the supermassive black holes, the structure of the interstellar plasma inhomogeneities and dynamics of compact objects in star-forming regions.

  1. Effects of a Randomized Reading Intervention Study Aimed at 9-Year-Olds: A 5-Year Follow-up.

    PubMed

    Wolff, Ulrika

    2016-05-01

    The present paper reports on a 5-year follow-up of a randomized reading intervention in grade 3 in Sweden. An intervention group (n = 57) received daily training for 12 weeks in phoneme/grapheme mapping, reading comprehension and reading speed, whereas a control group (n = 55) participated in ordinary classroom activities. The main aim was to investigate if there were remaining effects of the intervention on reading-related skills. Previous analyses showed that the intervention group performed significantly better than the control group on spelling, reading speed, reading comprehension and phoneme awareness at the immediate post-test with sustained effects 1 year later. Results from the 5-year follow-up show that the only significant difference between the intervention (n = 47) and the control group (n = 37) was on word decoding. There was also a significant interaction effect of group assignment and initial word decoding, in the way that the lowest-performing students benefitted the most from the intervention. Another aim was to examine if the children identified in a screening (n = 2212) as poor readers in grade 2 still performed worse than typical readers. The analyses showed that the typically developing students (n = 66) outperformed the students identified as poor readers in grade 2 on working memory, spelling, reading comprehension and word decoding. Copyright © 2016 John Wiley & Sons, Ltd. PMID:27146373

  2. Selecting object pairs for action: Is the active object always first?

    PubMed

    Laverick, Rosanna; Wulff, Melanie; Honisch, Juliane J; Chua, Wei Ling; Wing, Alan M; Rotshtein, Pia

    2015-08-01

    Perception is linked to action via two routes: a direct route based on affordance information in the environment and an indirect route based on semantic knowledge about objects. The present study explored the factors modulating the recruitment of the two routes, in particular which factors affecting the selection of paired objects. In Experiment 1, we presented real objects among semantically related or unrelated distracters. Participants had to select two objects that can interact. The presence of distracters affected selection times, but not the semantic relations of the objects with the distracters. Furthermore, participants first selected the active object (e.g. teaspoon) with their right hand, followed by the passive object (e.g. mug), often with their left hand. In Experiment 2, we presented pictures of the same objects with no hand grip, congruent or incongruent hand grip. Participants had to decide whether the two objects can interact. Action decisions were faster when the presentation of the active object preceded the presentation of the passive object, and when the grip was congruent. Interestingly, participants were slower when the objects were semantically but not functionally related; this effect increased with congruently gripped objects. Our data showed that action decisions in the presence of strong affordance cues (real objects, pictures of congruently gripped objects) relied on sensory-motor representation, supporting the direct route from perception-to-action that bypasses semantic knowledge. However, in the case of weak affordance cues (pictures), semantic information interfered with action decisions, indicating that semantic knowledge impacts action decisions. The data support the dual-route account from perception-to-action. PMID:25929555

  3. Characterizing the dependence of thick-mask edge effects on illumination angle using AIMS images

    NASA Astrophysics Data System (ADS)

    Shanker, Aamod; Sczyrba, Martin; Lange, Falk; Connolly, Brid; Neureuther, Andy; Waller, Laura

    2015-03-01

    Mask topography contributes diffraction-induced phase near edges, affecting the through-focus intensity variation and hence the process window at the wafer. We analyze the impact of edge diffraction on projection printing directly with experiments on an aerial image measurement system (AIMS). We show here that topographic effects change with illumination angle and can be quantified using through-focus intensity measurements. Off- axis incidence influences not just defocus image behavior (as for normal incidence), but also the at-focus intensity at wafer. Moreover, with oblique illumination, mask diffraction varies for left-facing and right-facing sidewalls, the nature of the asymmetry being polarization dependent. The image degradation due the polarization parallel to the sidewall (TE) is seen to be stronger, owing to the interplay of mask topography and pupil filtering in the imaging system. This translates to a CD variation of 2% between the two polarizations, even at focus. A simple thin-mask boundary layer model that treats each sidewall independently is shown to be able to approximate mask topography induced diffraction for both polarizations with 5-10nm wide boundary layers.

  4. Educational strategies aimed at improving student nurse's medication calculation skills: a review of the research literature.

    PubMed

    Stolic, Snezana

    2014-09-01

    Medication administration is an important and essential nursing function with the potential for dangerous consequences if errors occur. Not only must nurses understand the use and outcomes of administering medications they must be able to calculate correct dosages. Medication administration and dosage calculation education occurs across the undergraduate program for student nurses. Research highlights inconsistencies in the approaches used by academics to enhance the student nurse's medication calculation abilities. The aim of this integrative review was to examine the literature available on effective education strategies for undergraduate student nurses on medication dosage calculations. A literature search of five health care databases: Sciencedirect, Cinahl, Pubmed, Proquest, Medline to identify journal articles between 1990 and 2012 was conducted. Research articles on medication calculation educational strategies were considered for inclusion in this review. The search yielded 266 papers of which 20 meet the inclusion criteria. A total of 5206 student nurse were included in the final review. The review revealed educational strategies fell into four types of strategies; traditional pedagogy, technology, psychomotor skills and blended learning. The results suggested student nurses showed some benefit from the different strategies; however more improvements could be made. More rigorous research into this area is needed. PMID:25001180

  5. Do Object-Category Selective Regions in the Ventral Visual Stream Represent Perceived Distance Information?

    ERIC Educational Resources Information Center

    Amit, Elinor; Mehoudar, Eyal; Trope, Yaacov; Yovel, Galit

    2012-01-01

    It is well established that scenes and objects elicit a highly selective response in specific brain regions in the ventral visual cortex. An inherent difference between these categories that has not been explored yet is their perceived distance from the observer (i.e. scenes are distal whereas objects are proximal). The current study aimed to test…

  6. Evidence that the rat hippocampus has contrasting roles in object recognition memory and object recency memory.

    PubMed

    Albasser, Mathieu M; Amin, Eman; Lin, Tzu-Ching E; Iordanova, Mihaela D; Aggleton, John P

    2012-10-01

    Adult rats with extensive, bilateral neurotoxic lesions of the hippocampus showed normal forgetting curves for object recognition memory, yet were impaired on closely related tests of object recency memory. The present findings point to specific mechanisms for temporal order information (recency) that are dependent on the hippocampus and do not involve object recognition memory. The object recognition tests measured rats exploring simultaneously presented objects, one novel and the other familiar. Task difficulty was varied by altering the retention delays after presentation of the familiar object, so creating a forgetting curve. Hippocampal lesions had no apparent effect, despite using an apparatus (bow-tie maze) where it was possible to give lists of objects that might be expected to increase stimulus interference. In contrast, the same hippocampal lesions impaired the normal preference for an older (less recent) familiar object over a more recent, familiar object. A correlation was found between the loss of septal hippocampal tissue and this impairment in recency memory. The dissociation in the present study between recognition memory (spared) and recency memory (impaired) was unusually compelling, because it was possible to test the same objects for both forms of memory within the same session and within the same apparatus. The object recency deficit is of additional interest as it provides an example of a nonspatial memory deficit following hippocampal damage. PMID:23025831

  7. GIS and remote sensing techniques integration aimed for the evaluation of the Esino catchment impact on coastal water quality

    NASA Astrophysics Data System (ADS)

    Brunori, Carlo A.; Oliveri, Stefano; Luzi, Lucia; Zilioli, Eugenio

    1998-10-01

    The main aim of this work, carried out in the framework of the PRISMA2 national research program (Research and Experimentation Program for the Adriatic Sea) was the definition of an appropriate working methodology which allowed to estimate the impact of the Esino drainage-basin (central Italy), and of the anthropic activities lying on it, on the coastal water quality of the Adriatic sea. This aim was pursued by integrating techniques and instruments of analyses, such as GIS and remote sensing, which are often and often employed in natural resources managing and planning. They allowed to generate a database easily updating, relative to a very large area which is strongly differentiated in its natural and anthropic features. The database contains raw data, provided by local public organizations managing the territory, information derived from elaboration of the previous data and remote sensed frames (acquired by the hyperspectral sensor MIVIS) purposely acquired to the aim of the study. It was after all generated an 'open' system, continually updating with environmental information before long available; moreover, were explored the potentialities of the MIVIS sensor (102 band, from the visible to the thermic IR) in the study of marine coastal water quality.

  8. A Study To Determine the Attainment of the Goals and Objectives of an Innovative Baccalaureate Nursing Program.

    ERIC Educational Resources Information Center

    Duncan, Marjorie

    The effectiveness of the Registered Nurse Pathway Program at the Hunter-Bellevue School of Nursing at Hunter College was evaluated. The program was designed to provide an innovative approach to the acquisition of professional nurse behaviors for employed registered technical nurses who desire a baccalaureate degree in nursing. A total of 68…

  9. [Development, aims and status quo of the EU animal disease law].

    PubMed

    Bätza, Hans-Joachim

    2012-01-01

    The development of EC legislation is outlined using swine fever and foot and mouth disease as an example, starting with the possibility of vaccinating against both animal diseases in the 1980s without substantially restricting trade with vaccinated animals or products of these animals, right up to a policy of non-vaccination with the realisation of the single market with significant restrictions on intra-Community trade if the option of an emergency vaccination were to be used.The restrictions associated with emergency vaccination are basically tantamount to a vaccination ban. To that extent, vaccination needs to be taken into consideration as an instrument of animal disease control under the EU animal health legislation currently being discussed, the aim being for vaccinated animals that have tested as virus-free to be able to be marketed without any restrictions. This will, however, only be possible if all stakeholders (EU, member states, World Organisation for Animal Health, industry, consumers) achieve a broad consensus. PMID:22372317

  10. Studies of compact objects with Einstein - Review and prospects

    NASA Technical Reports Server (NTRS)

    Grindlay, Jonathan E.

    1990-01-01

    X-ray images and spectra of a wide range of systems containing compact objects were obtained with the Einstein X-ray Observatory. Accreting white dwarfs, neutron stars and black holes were observed in binary systems in the Galaxy, and new constraints were derived for their formation, nature and evolution. Massive black holes were studied in active galactic nuclei, and X-ray spectra (and evolution) of AGN have led to a new model for the diffuse X-ray background.

  11. The Open Learning Object Model to Promote Open Educational Resources

    ERIC Educational Resources Information Center

    Fulantelli, Giovanni; Gentile, Manuel; Taibi, Davide; Allegra, Mario

    2008-01-01

    In this paper we present the results of research work, that forms part of the activities of the EU-funded project SLOOP: Sharing Learning Objects in an Open Perspective, aimed at encouraging the definition, development and management of Open Educational Resources based on the Learning Object paradigm (Wiley, 2000). We present a model of Open…

  12. Aiming to Complete the Matrix: Eye-Movement Analysis of Processing Strategies in Children's Relational Thinking

    ERIC Educational Resources Information Center

    Chen, Zhe; Honomichl, Ryan; Kennedy, Diane; Tan, Enda

    2016-01-01

    The present study examines 5- to 8-year-old children's relation reasoning in solving matrix completion tasks. This study incorporates a componential analysis, an eye-tracking method, and a microgenetic approach, which together allow an investigation of the cognitive processing strategies involved in the development and learning of children's…

  13. A Taxonomic Description of the Science Integrating Learning Objectives in Career and Technical Education Programs of Study

    ERIC Educational Resources Information Center

    Spindler, Matthew

    2010-01-01

    The integration of career and technical education (CTE) and academic curricular content that capitalizes on natural and inherent connections represents a challenge for CTE professionals. The purpose of this study was to employ Bloom's revised taxonomy (Anderson, Krathwohl, Airasian, Cruiskshank, Mayer, Pintrich, Raths, & Wittrock, 2001) to…

  14. Persistence of the Intuitive Conception That Heavier Objects Sink More: A Reaction Time Study with Different Levels of Interference

    ERIC Educational Resources Information Center

    Potvin, Patrice; Masson, Steve; Lafortune, Stéphanie; Cyr, Guillaume

    2015-01-01

    Recent research efforts have argued for the "persistence" of some of students' frequent scientific misconceptions, even after correct answers are produced. Some of these studies, based on the analysis of reaction times, have recorded latencies for counter-intuitive or incongruent stimuli compared to intuitive or congruent ones. The…

  15. Once a myth, now an object of study - How the perception of comets has changed over the centuries

    NASA Astrophysics Data System (ADS)

    2004-02-01

    In February 2004, Rosetta will be setting off on its long journey through our solar system to meet up with Comet Churyumov-Gerasimenko. It will take the European Space Agency (ESA) space probe ten years to reach its destination. The comet, which moves in an elliptical orbit around the Sun, will at rendezvous be some 675 million kilometres from the Sun, near the point in its orbit farthest from the Sun. The meeting point was not chosen at random: at this point the comet is still barely active, it is still in fact a frozen lump of ice and interplanetary dust, in all probability the matter from which our solar system emerged four and a half billion years ago. Rosetta’s job is to find out more about these strange bodies that travel through our solar system. As it moves on, the comet will begin to change. As it approaches the Sun, it will - like all comets - become active: in the warmth of the Sun’s rays, the ices evaporate, tearing small dust particles from the surface. This produces the comet head (the coma) and tail. Only these two phenomena are visible from Earth. The comet nucleus itself is far too tiny - Churyumov-Gerasimenko measures about 4 kilometres across - to be viewed from Earth. As Dr Uwe Keller of the Max Planck Institute for Aeronomy in Kaltenburg-Lindau, the scientist responsible for the Osiris camera carried by Rosetta, explains, “Formation of the coma and tail during solar flyby skims several metres of matter off the comet’s surface. In the case of a small comet like Churyumov-Gerasimenko, the shrinkage is a good 1% each time round.” As it flies past the Sun every 6.6 years it can look forward to a short future, especially on a cosmic timescale. Comets - a mystical view Visible cometary phenomena have fascinated human beings from time immemorial - and frightened them too. Even today mystical explanations prevail among some of the Earth’s peoples. The Andaman islanders, a primitive people living in the Gulf of Bengal, see comets as burning

  16. Taking aim at Alzheimer’s disease through the mammalian target of rapamycin

    PubMed Central

    Maiese, Kenneth

    2014-01-01

    A significant portion of the world’s population suffers from sporadic Alzheimer’s disease (AD) with available present therapies limited to symptomatic care that does not alter disease progression. Over the next decade, advancing age of the global population will dramatically increase the incidence of AD and severely impact health care resources, necessitating novel, safe, and efficacious strategies for AD. The mammalian target of rapamycin (mTOR) and its protein complexes mTOR Complex 1 (mTORC1) and mTOR Complex 2 (mTORC2) offer exciting and unique avenues of intervention for AD through the oversight of programmed cell death pathways of apoptosis, autophagy, and necroptosis. mTOR modulates multi-faceted signal transduction pathways that involve phosphoinositide 3-kinase (PI 3-K), protein kinase B (Akt), hamartin (tuberous sclerosis 1)/tuberin (tuberous sclerosis 2) (TSC1/TSC2) complex, proline-rich Akt substrate 40 kDa (PRAS40), and p70 ribosomal S6 kinase (p70S6K) and can interface with the neuroprotective pathways of growth factors, sirtuins, wingless, fork-head transcription factors, and glycogen synthase kinase-3β. With the ability of mTOR to broadly impact cellular function, clinical strategies for AD that implement mTOR must achieve parallel objectives of protecting neuronal, vascular, and immune cell survival in conjunction with preserving networks that determine memory and cognitive function. PMID:25105207

  17. Once a myth, now an object of study - How the perception of comets has changed over the centuries

    NASA Astrophysics Data System (ADS)

    2004-02-01

    In February 2004, Rosetta will be setting off on its long journey through our solar system to meet up with Comet Churyumov-Gerasimenko. It will take the European Space Agency (ESA) space probe ten years to reach its destination. The comet, which moves in an elliptical orbit around the Sun, will at rendezvous be some 675 million kilometres from the Sun, near the point in its orbit farthest from the Sun. The meeting point was not chosen at random: at this point the comet is still barely active, it is still in fact a frozen lump of ice and interplanetary dust, in all probability the matter from which our solar system emerged four and a half billion years ago. Rosetta’s job is to find out more about these strange bodies that travel through our solar system. As it moves on, the comet will begin to change. As it approaches the Sun, it will - like all comets - become active: in the warmth of the Sun’s rays, the ices evaporate, tearing small dust particles from the surface. This produces the comet head (the coma) and tail. Only these two phenomena are visible from Earth. The comet nucleus itself is far too tiny - Churyumov-Gerasimenko measures about 4 kilometres across - to be viewed from Earth. As Dr Uwe Keller of the Max Planck Institute for Aeronomy in Kaltenburg-Lindau, the scientist responsible for the Osiris camera carried by Rosetta, explains, “Formation of the coma and tail during solar flyby skims several metres of matter off the comet’s surface. In the case of a small comet like Churyumov-Gerasimenko, the shrinkage is a good 1% each time round.” As it flies past the Sun every 6.6 years it can look forward to a short future, especially on a cosmic timescale. Comets - a mystical view Visible cometary phenomena have fascinated human beings from time immemorial - and frightened them too. Even today mystical explanations prevail among some of the Earth’s peoples. The Andaman islanders, a primitive people living in the Gulf of Bengal, see comets as burning

  18. The Experience of Doctoral Studies in the UK and France: Differences in Epistemology, Research Objects and Training

    ERIC Educational Resources Information Center

    Chiang, Kuang-Hsu

    2011-01-01

    This article investigates how doctoral students perceive their research education in different disciplines in two higher education systems, the UK and France. It explores what underlies the diversity of doctoral students' experiences. Three theoretical positions are identified: the epistemological position, conceptualisation of research objects…

  19. A cluster randomized controlled trial aimed at implementation of local quality improvement collaboratives to improve prescribing and test ordering performance of general practitioners: Study Protocol

    PubMed Central

    Trietsch, Jasper; van der Weijden, Trudy; Verstappen, Wim; Janknegt, Rob; Muijrers, Paul; Winkens, Ron; van Steenkiste, Ben; Grol, Richard; Metsemakers, Job

    2009-01-01

    Background The use of guidelines in general practice is not optimal. Although evidence-based methods to improve guideline adherence are available, variation in physician adherence to general practice guidelines remains relatively high. The objective for this study is to transfer a quality improvement strategy based on audit, feedback, educational materials, and peer group discussion moderated by local opinion leaders to the field. The research questions are: is the multifaceted strategy implemented on a large scale as planned?; what is the effect on general practitioners' (GPs) test ordering and prescribing behaviour?; and what are the costs of implementing the strategy? Methods In order to evaluate the effects, costs and feasibility of this new strategy we plan a multi-centre cluster randomized controlled trial (RCT) with a balanced incomplete block design. Local GP groups in the south of the Netherlands already taking part in pharmacotherapeutic audit meeting groups, will be recruited by regional health officers. Approximately 50 groups of GPs will be randomly allocated to two arms. These GPs will be offered two different balanced sets of clinical topics. Each GP within a group will receive comparative feedback on test ordering and prescribing performance. The feedback will be discussed in the group and working agreements will be created after discussion of the guidelines and barriers to change. The data for the feedback will be collected from existing and newly formed databases, both at baseline and after one year. Discussion We are not aware of published studies on successes and failures of attempts to transfer to the stakeholders in the field a multifaceted strategy aimed at GPs' test ordering and prescribing behaviour. This pragmatic study will focus on compatibility with existing infrastructure, while permitting a certain degree of adaptation to local needs and routines. Trial registration Nederlands Trial Register ISRCTN40008171 PMID:19222840

  20. The Earliest Lead Object in the Levant

    PubMed Central

    Yahalom-Mack, Naama; Langgut, Dafna; Dvir, Omri; Tirosh, Ofir; Eliyahu-Behar, Adi; Erel, Yigal; Langford, Boaz; Frumkin, Amos; Ullman, Mika; Davidovich, Uri

    2015-01-01

    In the deepest section of a large complex cave in the northern Negev desert, Israel, a bi-conical lead object was found logged onto a wooden shaft. Associated material remains and radiocarbon dating of the shaft place the object within the Late Chalcolithic period, at the late 5th millennium BCE. Based on chemical and lead isotope analysis, we show that this unique object was made of almost pure metallic lead, likely smelted from lead ores originating in the Taurus range in Anatolia. Either the finished object, or the raw material, was brought to the southern Levant, adding another major component to the already-rich Late Chalcolithic metallurgical corpus known to-date. The paper also discusses possible uses of the object, suggesting that it may have been used as a spindle whorl, at least towards its deposition. PMID:26630666

  1. The Earliest Lead Object in the Levant.

    PubMed

    Yahalom-Mack, Naama; Langgut, Dafna; Dvir, Omri; Tirosh, Ofir; Eliyahu-Behar, Adi; Erel, Yigal; Langford, Boaz; Frumkin, Amos; Ullman, Mika; Davidovich, Uri

    2015-01-01

    In the deepest section of a large complex cave in the northern Negev desert, Israel, a bi-conical lead object was found logged onto a wooden shaft. Associated material remains and radiocarbon dating of the shaft place the object within the Late Chalcolithic period, at the late 5th millennium BCE. Based on chemical and lead isotope analysis, we show that this unique object was made of almost pure metallic lead, likely smelted from lead ores originating in the Taurus range in Anatolia. Either the finished object, or the raw material, was brought to the southern Levant, adding another major component to the already-rich Late Chalcolithic metallurgical corpus known to-date. The paper also discusses possible uses of the object, suggesting that it may have been used as a spindle whorl, at least towards its deposition. PMID:26630666

  2. Research Networking Systems: The State of Adoption at Institutions Aiming to Augment Translational Research Infrastructure

    PubMed Central

    Obeid, Jihad S; Johnson, Layne M; Stallings, Sarah; Eichmann, David

    2015-01-01

    Fostering collaborations across multiple disciplines within and across institutional boundaries is becoming increasingly important with the growing emphasis on translational research. As a result, Research Networking Systems that facilitate discovery of potential collaborators have received significant attention by institutions aiming to augment their research infrastructure. We have conducted a survey to assess the state of adoption of these new tools at the Clinical and Translational Science Award (CTSA) funded institutions. Survey results demonstrate that most CTSA funded institutions have either already adopted or were planning to adopt one of several available research networking systems. Moreover a good number of these institutions have exposed or plan to expose the data on research expertise using linked open data, an established approach to semantic web services. Preliminary exploration of these publically-available data shows promising utility in assessing cross-institutional collaborations. Further adoption of these technologies and analysis of the data are needed, however, before their impact on cross-institutional collaboration in research can be appreciated and measured. PMID:26491707

  3. Low-Income Employees’ Choices Regarding Employment Benefits Aimed at Improving the Socioeconomic Determinants of Health

    PubMed Central

    Danis, Marion; Lovett, Francis; Sabik, Lindsay; Adikes, Katherin; Cheng, Glen; Aomo, Tom

    2007-01-01

    Objectives. Socioeconomic factors are associated with reduced health status in low-income populations. We sought to identify affordable employment benefit packages that might ameliorate these socioeconomic factors and would be consonant with employees’ priorities. Methods. Working in groups (n = 53), low-income employees (n = 408; 62% women, 65% Black) from the Washington, DC, and Baltimore, Md, metropolitan area, participated in a computerized exercise in which they expressed their preference for employment benefit packages intended to address socioeconomic determinants of health. The hypothetical costs of these benefits reflected those of the average US benefit package available to low-income employees. Questionnaires ascertained sociodemographic information and attitudes. Descriptive statistics and logistic regression analysis were used to examine benefit choices. Results. Groups chose offered benefits in the following descending rank order: health care, retirement, vacation, disability pay, training, job flexibility, family time, dependent care, monetary advice, anxiety assistance, wellness, housing assistance, and nutrition programs. Participants varied in their personal choices, but 78% expressed willingness to abide by their groups’ choices. Conclusions. It is possible to design employment benefits that ameliorate socioeconomic determinants of health and are acceptable to low-income employees. These benefit packages can be provided at the cost of benefit packages currently available to some low-income employees. PMID:17666702

  4. A Comparative Study of Achievement in the Concepts of Fundamentals of Geometry Taught by Computer Managed Individualized Behavioral Objective Instructional Units Versus Lecture-Demonstration Methods of Instruction.

    ERIC Educational Resources Information Center

    Fisher, Merrill Edgar

    The purposes of this study were (1) to identify and compare the effect on student achievement of an individualized computer-managed geometry course, built on behavioral objectives, with traditional instructional methods; and (2) to identify how selected individual aptitudes interact with the two instructional modes. The subjects were…

  5. The Receptor for Advanced Glycation End Products Activates the AIM2 Inflammasome in Acute Pancreatitis.

    PubMed

    Kang, Rui; Chen, Ruochan; Xie, Min; Cao, Lizhi; Lotze, Michael T; Tang, Daolin; Zeh, Herbert J

    2016-05-15

    Severe acute pancreatitis (AP) is responsible for significant human morbidity and mortality worldwide. Currently, no specific treatments for AP exist, primarily due to the lack of a mechanistic understanding of sterile inflammation and the resultant multisystem organ dysfunction, the pathologic response of AP linked to early death. In this study, we demonstrate that