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Sample records for subfunctionalization provide specialized

  1. Analyses of fugu hoxa2 genes provide evidence for subfunctionalization of neural crest cell and rhombomere cis-regulatory modules during vertebrate evolution.

    PubMed

    McEllin, Jennifer A; Alexander, Tara B; Tümpel, Stefan; Wiedemann, Leanne M; Krumlauf, Robb

    2016-01-15

    Hoxa2 gene is a primary player in regulation of craniofacial programs of head development in vertebrates. Here we investigate the evolution of a Hoxa2 neural crest enhancer identified originally in mouse by comparing and contrasting the fugu hoxa2a and hoxa2b genes with their orthologous teleost and mammalian sequences. Using sequence analyses in combination with transgenic regulatory assays in zebrafish and mouse embryos we demonstrate subfunctionalization of regulatory activity for expression in hindbrain segments and neural crest cells between these two fugu co-orthologs. hoxa2a regulatory sequences have retained the ability to mediate expression in neural crest cells while those of hoxa2b include cis-elements that direct expression in rhombomeres. Functional dissection of the neural crest regulatory potential of the fugu hoxa2a and hoxa2b genes identify the previously unknown cis-element NC5, which is implicated in generating the differential activity of the enhancers from these genes. The NC5 region plays a similar role in the ability of this enhancer to mediate reporter expression in mice, suggesting it is a conserved component involved in control of neural crest expression of Hoxa2 in vertebrate craniofacial development. PMID:26632170

  2. Multiple Routes to Subfunctionalization and Gene Duplicate Specialization

    PubMed Central

    Proulx, Stephen R.

    2012-01-01

    Gene duplication is arguably the most significant source of new functional genetic material. A better understanding of the processes that lead to the stable incorporation of gene duplications into the genome is important both because it relates to interspecific differences in genome composition and because it can shed light on why some classes of gene are more prone to duplication than others. Typically, models of gene duplication consider the periods before duplication, during the spread and fixation of a new duplicate, and following duplication as distinct phases without a common underlying selective environment. I consider a scenario where a gene that is initially expressed in multiple contexts can undergo mutations that alter its expression profile or its functional coding sequence. The selective regime that acts on the functional output of the allele copies carried by an individual is constant. If there is a potential selective benefit to having different coding sequences expressed in each context, then, regardless of the constraints on functional variation at the single-locus gene, the waiting time until a gene duplication is incorporated goes down as population size increases. PMID:22143920

  3. Vitellogenin Underwent Subfunctionalization to Acquire Caste and Behavioral Specific Expression in the Harvester Ant Pogonomyrmex barbatus

    PubMed Central

    Wurm, Yannick; Riba-Grognuz, Oksana; Studer, Romain A.; Keller, Laurent

    2013-01-01

    The reproductive ground plan hypothesis (RGPH) proposes that the physiological pathways regulating reproduction were co-opted to regulate worker division of labor. Support for this hypothesis in honeybees is provided by studies demonstrating that the reproductive potential of workers, assessed by the levels of vitellogenin (Vg), is linked to task performance. Interestingly, contrary to honeybees that have a single Vg ortholog and potentially fertile nurses, the genome of the harvester ant Pogonomyrmex barbatus harbors two Vg genes (Pb_Vg1 and Pb_Vg2) and nurses produce infertile trophic eggs. P. barbatus, thus, provides a unique model to investigate whether Vg duplication in ants was followed by subfunctionalization to acquire reproductive and non-reproductive functions and whether Vg reproductive function was co-opted to regulate behavior in sterile workers. To investigate these questions, we compared the expression patterns of P. barbatus Vg genes and analyzed the phylogenetic relationships and molecular evolution of Vg genes in ants. qRT-PCRs revealed that Pb_Vg1 is more highly expressed in queens compared to workers and in nurses compared to foragers. By contrast, the level of expression of Pb_Vg2 was higher in foragers than in nurses and queens. Phylogenetic analyses show that a first duplication of the ancestral Vg gene occurred after the divergence between the poneroid and formicoid clades and subsequent duplications occurred in the lineages leading to Solenopsis invicta, Linepithema humile and Acromyrmex echinatior. The initial duplication resulted in two Vg gene subfamilies preferentially expressed in queens and nurses (subfamily A) or in foraging workers (subfamily B). Finally, molecular evolution analyses show that the subfamily A experienced positive selection, while the subfamily B showed overall relaxation of purifying selection. Our results suggest that in P. barbatus the Vg gene underwent subfunctionalization after duplication to acquire caste- and

  4. Model of Providing Assistive Technologies in Special Education Schools

    PubMed Central

    Lersilp, Suchitporn; Putthinoi, Supawadee; Chakpitak, Nopasit

    2016-01-01

    Most students diagnosed with disabilities in Thai special education schools received assistive technologies, but this did not guarantee the greatest benefits. The purpose of this study was to survey the provision, use and needs of assistive technologies, as well as the perspectives of key informants regarding a model of providing them in special education schools. The participants were selected by the purposive sampling method, and they comprised 120 students with visual, physical, hearing or intellectual disabilities from four special education schools in Chiang Mai, Thailand; and 24 key informants such as parents or caregivers, teachers, school principals and school therapists. The instruments consisted of an assistive technology checklist and a semi-structured interview. Results showed that a category of assistive technologies was provided for students with disabilities, with the highest being “services”, followed by “media” and then “facilities”. Furthermore, mostly students with physical disabilities were provided with assistive technologies, but those with visual disabilities needed it more. Finally, the model of providing assistive technologies was composed of 5 components: Collaboration; Holistic perspective; Independent management of schools; Learning systems and a production manual for users; and Development of an assistive technology center, driven by 3 major sources such as Government and Private organizations, and Schools. PMID:26234984

  5. Subfunctionalization and neofunctionalization of vertebrate Lef/Tcf transcription factors.

    PubMed

    Klingel, Susanne; Morath, Iris; Strietz, Juliane; Menzel, Katharina; Holstein, Thomas W; Gradl, Dietmar

    2012-08-01

    Invertebrates express a multitude of Wnt ligands and all Wnt/β-catenin signaling pathways converge to only one nuclear Lef/Tcf. In vertebrates, however, four distinct Lef/Tcfs, i.e. Tcf-1, Lef, Tcf-3, and Tcf-4 fulfill this function. At present, it is largely unknown to what extent the various Lef/Tcfs are functionally similar or diversified in vertebrates. In particular, it is not known which domains are responsible for the Tcf subtype specific functions. We investigated the conserved and non-conserved functions of the various Tcfs by using Xenopus laevis as a model organism and testing Tcfs from Hydra magnipapillata, Caenorhabditis elegans and Drosophila melanogaster. In order to identify domains relevant for the individual properties we created series of chimeric constructs consisting of parts of XTcf-3, XTcf-1 and HyTcf. Rescue experiments in Xenopus morphants revealed that the three invertebrate Tcfs tested compensated the loss of distinct Xenopus Tcfs: Drosophila Tcf (Pangolin) can substitute for the loss of XTcf-1, XTcf-3 and XTcf-4. By comparison, Caenorhabditis Tcf (Pop-1) and Hydra Tcf (HyTcf) can substitute for the loss of only XTcf-3 and XTcf-4, respectively. The domain, which is responsible for subtype specific functions is the regulatory CRD domain. A phylogenetic analysis separates Tcf-1/Lef-1 from the sister group Tcf-3/4 in the vertebrate lineage. We propose that the vertebrate specific diversification of Tcfs in vertebrates resulted in subfunctionalization of a Tcf that already united most of the Lef/Tcf functions. PMID:22641013

  6. Subfunctionalization of Duplicated Zebrafish pax6 Genes by cis-Regulatory Divergence

    PubMed Central

    Gautier, Philippe; Dahm, Ralf; Schonthaler, Helia B; Damante, Giuseppe; Seawright, Anne; Hever, Ann M; Yeyati, Patricia L; van Heyningen, Veronica; Coutinho, Pedro

    2008-01-01

    Gene duplication is a major driver of evolutionary divergence. In most vertebrates a single PAX6 gene encodes a transcription factor required for eye, brain, olfactory system, and pancreas development. In zebrafish, following a postulated whole-genome duplication event in an ancestral teleost, duplicates pax6a and pax6b jointly fulfill these roles. Mapping of the homozygously viable eye mutant sunrise identified a homeodomain missense change in pax6b, leading to loss of target binding. The mild phenotype emphasizes role-sharing between the co-orthologues. Meticulous mapping of isolated BACs identified perturbed synteny relationships around the duplicates. This highlights the functional conservation of pax6 downstream (3′) control sequences, which in most vertebrates reside within the introns of a ubiquitously expressed neighbour gene, ELP4, whose pax6a-linked exons have been lost in zebrafish. Reporter transgenic studies in both mouse and zebrafish, combined with analysis of vertebrate sequence conservation, reveal loss and retention of specific cis-regulatory elements, correlating strongly with the diverged expression of co-orthologues, and providing clear evidence for evolution by subfunctionalization. PMID:18282108

  7. Evolution of selenophosphate synthetases: emergence and relocation of function through independent duplications and recurrent subfunctionalization

    PubMed Central

    Mariotti, Marco; Santesmasses, Didac; Capella-Gutierrez, Salvador; Mateo, Andrea; Arnan, Carme; Johnson, Rory; D'Aniello, Salvatore; Yim, Sun Hee; Gladyshev, Vadim N.; Serras, Florenci; Corominas, Montserrat; Gabaldón, Toni; Guigó, Roderic

    2015-01-01

    Selenoproteins are proteins that incorporate selenocysteine (Sec), a nonstandard amino acid encoded by UGA, normally a stop codon. Sec synthesis requires the enzyme Selenophosphate synthetase (SPS or SelD), conserved in all prokaryotic and eukaryotic genomes encoding selenoproteins. Here, we study the evolutionary history of SPS genes, providing a map of selenoprotein function spanning the whole tree of life. SPS is itself a selenoprotein in many species, although functionally equivalent homologs that replace the Sec site with cysteine (Cys) are common. Many metazoans, however, possess SPS genes with substitutions other than Sec or Cys (collectively referred to as SPS1). Using complementation assays in fly mutants, we show that these genes share a common function, which appears to be distinct from the synthesis of selenophosphate carried out by the Sec- and Cys- SPS genes (termed SPS2), and unrelated to Sec synthesis. We show here that SPS1 genes originated through a number of independent gene duplications from an ancestral metazoan selenoprotein SPS2 gene that most likely already carried the SPS1 function. Thus, in SPS genes, parallel duplications and subsequent convergent subfunctionalization have resulted in the segregation to different loci of functions initially carried by a single gene. This evolutionary history constitutes a remarkable example of emergence and evolution of gene function, which we have been able to trace thanks to the singular features of SPS genes, wherein the amino acid at a single site determines unequivocally protein function and is intertwined to the evolutionary fate of the entire selenoproteome. PMID:26194102

  8. Evolution of selenophosphate synthetases: emergence and relocation of function through independent duplications and recurrent subfunctionalization.

    PubMed

    Mariotti, Marco; Santesmasses, Didac; Capella-Gutierrez, Salvador; Mateo, Andrea; Arnan, Carme; Johnson, Rory; D'Aniello, Salvatore; Yim, Sun Hee; Gladyshev, Vadim N; Serras, Florenci; Corominas, Montserrat; Gabaldón, Toni; Guigó, Roderic

    2015-09-01

    Selenoproteins are proteins that incorporate selenocysteine (Sec), a nonstandard amino acid encoded by UGA, normally a stop codon. Sec synthesis requires the enzyme Selenophosphate synthetase (SPS or SelD), conserved in all prokaryotic and eukaryotic genomes encoding selenoproteins. Here, we study the evolutionary history of SPS genes, providing a map of selenoprotein function spanning the whole tree of life. SPS is itself a selenoprotein in many species, although functionally equivalent homologs that replace the Sec site with cysteine (Cys) are common. Many metazoans, however, possess SPS genes with substitutions other than Sec or Cys (collectively referred to as SPS1). Using complementation assays in fly mutants, we show that these genes share a common function, which appears to be distinct from the synthesis of selenophosphate carried out by the Sec- and Cys- SPS genes (termed SPS2), and unrelated to Sec synthesis. We show here that SPS1 genes originated through a number of independent gene duplications from an ancestral metazoan selenoprotein SPS2 gene that most likely already carried the SPS1 function. Thus, in SPS genes, parallel duplications and subsequent convergent subfunctionalization have resulted in the segregation to different loci of functions initially carried by a single gene. This evolutionary history constitutes a remarkable example of emergence and evolution of gene function, which we have been able to trace thanks to the singular features of SPS genes, wherein the amino acid at a single site determines unequivocally protein function and is intertwined to the evolutionary fate of the entire selenoproteome. PMID:26194102

  9. Subfunctionalization of duplicated zebrafish pax6 genes by cis-regulatory divergence.

    PubMed

    Kleinjan, Dirk A; Bancewicz, Ruth M; Gautier, Philippe; Dahm, Ralf; Schonthaler, Helia B; Damante, Giuseppe; Seawright, Anne; Hever, Ann M; Yeyati, Patricia L; van Heyningen, Veronica; Coutinho, Pedro

    2008-02-01

    Gene duplication is a major driver of evolutionary divergence. In most vertebrates a single PAX6 gene encodes a transcription factor required for eye, brain, olfactory system, and pancreas development. In zebrafish, following a postulated whole-genome duplication event in an ancestral teleost, duplicates pax6a and pax6b jointly fulfill these roles. Mapping of the homozygously viable eye mutant sunrise identified a homeodomain missense change in pax6b, leading to loss of target binding. The mild phenotype emphasizes role-sharing between the co-orthologues. Meticulous mapping of isolated BACs identified perturbed synteny relationships around the duplicates. This highlights the functional conservation of pax6 downstream (3') control sequences, which in most vertebrates reside within the introns of a ubiquitously expressed neighbour gene, ELP4, whose pax6a-linked exons have been lost in zebrafish. Reporter transgenic studies in both mouse and zebrafish, combined with analysis of vertebrate sequence conservation, reveal loss and retention of specific cis-regulatory elements, correlating strongly with the diverged expression of co-orthologues, and providing clear evidence for evolution by subfunctionalization. PMID:18282108

  10. 41 CFR 102-85.195 - Does GSA provide special services?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Does GSA provide special services? 102-85.195 Section 102-85.195 Public Contracts and Property Management Federal Property... OCCUPANCY IN GSA SPACE Special Services § 102-85.195 Does GSA provide special services? Yes, GSA...

  11. 41 CFR 102-85.195 - Does GSA provide special services?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Does GSA provide special services? 102-85.195 Section 102-85.195 Public Contracts and Property Management Federal Property... OCCUPANCY IN GSA SPACE Special Services § 102-85.195 Does GSA provide special services? Yes, GSA...

  12. Characteristics of Swedish Preschools That Provide Education and Care to Children with Special Educational Needs

    ERIC Educational Resources Information Center

    Lundqvist, Johanna; Westling, Mara Allodi; Siljehag, Eva

    2016-01-01

    In Sweden, preschool inclusion is embraced and preschools are open for children both with and without special educational needs. The purpose of this study was to examine the characteristics of a number of preschool units in Sweden that provide education and care to children with special educational needs with regard to organisation, resources and…

  13. 48 CFR 1545.309 - Providing Government production and research property under special restrictions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... production and research property under special restrictions. 1545.309 Section 1545.309 Federal Acquisition... Government Property to Contractors 1545.309 Providing Government production and research property under special restrictions. Government production and research property, other than foundations and...

  14. 41 CFR 102-85.195 - Does GSA provide special services?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 85-PRICING POLICY FOR... bill amount. The bill amount for separable special services is either based on a previously agreed upon... special services on a cost-reimbursable basis: (a) In GSA-controlled space, GSA may provide for...

  15. Petal-specific subfunctionalization of an APETALA3 paralog in the Ranunculales and its implications for petal evolution.

    PubMed

    Sharma, Bharti; Guo, Chunce; Kong, Hongzhi; Kramer, Elena M

    2011-08-01

    • The petals of the lower eudicot family Ranunculaceae are thought to have been derived many times independently from stamens. However, investigation of the genetic basis of their identity has suggested an alternative hypothesis: that they share a commonly inherited petal identity program. This theory is based on the fact that an ancient paralogous lineage of APETALA3 (AP3) in the Ranunculaceae appears to have a conserved, petal-specific expression pattern. • Here, we have used a combination of approaches, including RNAi, comparative gene expression and molecular evolutionary studies, to understand the function of this petal-specific AP3 lineage. • Functional analysis of the Aquilegia locus AqAP3-3 has demonstrated that the paralog is required for petal identity with little contribution to the identity of the other floral organs. Expanded expression studies and analyses of molecular evolutionary patterns provide further evidence that orthologs of AqAP3-3 are primarily expressed in petals and are under higher purifying selection across the family than the other AP3 paralogs. • Taken together, these findings suggest that the AqAP3-3 lineage underwent progressive subfunctionalization within the order Ranunculales, ultimately yielding a specific role in petal identity that has probably been conserved, in stark contrast with the multiple independent origins predicted by botanical theories. PMID:21557746

  16. For the Children. Building Partnerships for Special Needs Children: A Parent and Provider Resource.

    ERIC Educational Resources Information Center

    Barnes, Deborah J.

    This manual provides information to assist individuals in working together more effectively to provide comprehensive services and improve outcomes for children with special health care needs. The manual emphasizes the need for a union of services that places the child and family at the center and exists to provide educational, medical/health, and…

  17. 75 FR 30410 - Disease, Disability, and Injury Prevention and Control Special Interest Project (SIP): Provider...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-01

    ... Control Special Interest Project (SIP): Provider and Public Health Input for Vaccine Policy Decisions SIP..., discussion, and evaluation of applications received in response to ``Provider and Public Health Input for... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  18. Coregulation of tandem duplicate genes slows evolution of subfunctionalization in mammals.

    PubMed

    Lan, Xun; Pritchard, Jonathan K

    2016-05-20

    Gene duplication is a fundamental process in genome evolution. However, most young duplicates are degraded by loss-of-function mutations, and the factors that allow some duplicate pairs to survive long-term remain controversial. One class of models to explain duplicate retention invokes sub- or neofunctionalization, whereas others focus on sharing of gene dosage. RNA-sequencing data from 46 human and 26 mouse tissues indicate that subfunctionalization of expression evolves slowly and is rare among duplicates that arose within the placental mammals, possibly because tandem duplicates are coregulated by shared genomic elements. Instead, consistent with the dosage-sharing hypothesis, most young duplicates are down-regulated to match expression levels of single-copy genes. Thus, dosage sharing of expression allows for the initial survival of mammalian duplicates, followed by slower functional adaptation enabling long-term preservation. PMID:27199432

  19. Public Special Services Provided to People with Intellectual Disabilities in Sweden: A Life-Span Perspective

    ERIC Educational Resources Information Center

    Umb-Carlsson, Oie

    2008-01-01

    This study describes public special services, support, and health care provided to an administratively defined county sample of people with intellectual disabilities from early childhood to adult age. Comparisons were made on the variables year of birth, sex, and assessed level of intellectual disabilities in 1974. Information was obtained from…

  20. Training and Resource Needs of Teachers Who Provide HIV Education to Special Population Students

    ERIC Educational Resources Information Center

    Sawyer, Richard J.; Blake, Susan; Ledsky, Rebecca; Goodenow, Carol; Evans, Doug

    2004-01-01

    This study identified substantial training and resource needs for special education (SPED), transitional bilingual education/ English as a Second Language (TBE/ESL), and general education (GENED) HIV education teachers relative to providing appropriate, effective HIV education to students with disabilities (SWD) and language minority/Limited…

  1. How the rice weevil breaks down the pectin network: Enzymatic synergism and sub-functionalization.

    PubMed

    Kirsch, Roy; Heckel, David G; Pauchet, Yannick

    2016-04-01

    Pectin is the most complex polysaccharide in nature and highly abundant in plant cell walls and middle lamellae, where it functions in plant growth and development. Phytopathogens utilize plant pectin as an energy source through enzyme-mediated degradation. These pectolytic enzymes include polygalacturonases (PGs) of the GH28 family and pectin methylesterases (PMEs) of the CE8 family. Recently, PGs were also identified in herbivorous insects of the distantly related plant bug, stick insect and Phytophaga beetle lineages. Unlike all other insects, weevils possess PMEs in addition to PGs. To investigate pectin digestion in insects and the role of PMEs in weevils, all PME and PG family members of the rice weevil Sitophilus oryzae were heterologously expressed and functionally characterized. Enzymatically active and inactive PG and PME family members were identified. The loss of activity can be explained by a lack of substrate binding correlating with substitutions of functionally important amino acid residues. We found subfunctionalization in both enzyme families, supported by expression pattern and substrate specificities as well as evidence for synergistic pectin breakdown. Our data suggest that the rice weevil might be able to use pectin as an energy source, and illustrates the potential of both PG and PME enzyme families to functionally diversify after horizontal gene transfer. PMID:26899322

  2. Subfunctionalization of duplicate mitf genes associated with differential degeneration of alternative exons in fish.

    PubMed Central

    Altschmied, Joachim; Delfgaauw, Jacqueline; Wilde, Brigitta; Duschl, Jutta; Bouneau, Laurence; Volff, Jean-Nicolas; Schartl, Manfred

    2002-01-01

    The microphthalmia-associated transcription factor (MITF) exists in at least four isoforms. These are generated in higher vertebrates using alternative 5' exons and promoters from a single gene. Two separate genes (mitf-m and mitf-b), however, are present in different teleost fish species including the poeciliid Xiphophorus, the pufferfishes Fugu rubripes and Tetraodon nigroviridis, and the zebrafish Danio rerio. Fish proteins MITF-m and MITF-b correspond at both the structural and the expression levels to one particular bird/mammalian MITF isoform. In the teleost lineage subfunctionalization of mitf genes after duplication at least 100 million years ago is associated with the degeneration of alternative exons and, probably, regulatory elements and promoters. For example, a remnant of the first exon specific for MITF-m is detected within the pufferfish gene encoding MITF-b. Retracing the evolutionary history of mitf genes in vertebrates uncovered the differential recruitment of new introns specific for either the teleost or the bird/mammalian lineage. PMID:12019239

  3. 42 CFR 482.66 - Special requirements for hospital providers of long-term care services (“swing-beds”).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Special requirements for hospital providers of long... PARTICIPATION FOR HOSPITALS Requirements for Specialty Hospitals § 482.66 Special requirements for hospital providers of long-term care services (“swing-beds”). A hospital that has a Medicare provider agreement...

  4. Sub-grouping and sub-functionalization of the RIFIN multi-copy protein family

    PubMed Central

    Joannin, Nicolas; Abhiman, Saraswathi; Sonnhammer, Erik L; Wahlgren, Mats

    2008-01-01

    Background Parasitic protozoans possess many multicopy gene families which have central roles in parasite survival and virulence. The number and variability of members of these gene families often make it difficult to predict possible functions of the encoded proteins. The families of extra-cellular proteins that are exposed to a host immune response have been driven via immune selection to become antigenically variant, and thereby avoid immune recognition while maintaining protein function to establish a chronic infection. Results We have combined phylogenetic and function shift analyses to study the evolution of the RIFIN proteins, which are antigenically variant and are encoded by the largest multicopy gene family in Plasmodium falciparum. We show that this family can be subdivided into two major groups that we named A- and B-RIFIN proteins. This suggested sub-grouping is supported by a recently published study that showed that, despite the presence of the Plasmodium export (PEXEL) motif in all RIFIN variants, proteins from each group have different cellular localizations during the intraerythrocytic life cycle of the parasite. In the present study we show that function shift analysis, a novel technique to predict functional divergence between sub-groups of a protein family, indicates that RIFINs have undergone neo- or sub-functionalization. Conclusion These results question the general trend of clustering large antigenically variant protein groups into homogenous families. Assigning functions to protein families requires their subdivision into meaningful groups such as we have shown for the RIFIN protein family. Using phylogenetic and function shift analysis methods, we identify new directions for the investigation of this broad and complex group of proteins. PMID:18197962

  5. Clusters of specialized detector cells provide sensitive and high fidelity receptor signaling in the intact endothelium.

    PubMed

    Wilson, Calum; Saunter, Christopher D; Girkin, John M; McCarron, John G

    2016-05-01

    Agonist-mediated signaling by the endothelium controls virtually all vascular functions. Because of the large diversity of agonists, each with varying concentrations, background noise often obscures individual cellular signals. How the endothelium distinguishes low-level fluctuations from noise and decodes and integrates physiologically relevant information remains unclear. Here, we recorded changes in intracellular Ca(2+) concentrations in response to acetylcholine in areas encompassing hundreds of endothelial cells from inside intact pressurized arteries. Individual cells responded to acetylcholine with a concentration-dependent increase in Ca(2+) signals spanning a single order of magnitude. Interestingly, however, intercellular response variation extended over 3 orders of magnitude of agonist concentration, thus crucially enhancing the collective bandwidth of endothelial responses to agonists. We also show the accuracy of this collective mode of detection is facilitated by spatially restricted clusters of comparably sensitive cells arising from heterogeneous receptor expression. Simultaneous stimulation of clusters triggered Ca(2+) signals that were transmitted to neighboring cells in a manner that scaled with agonist concentration. Thus, the endothelium detects agonists by acting as a distributed sensing system. Specialized clusters of detector cells, analogous to relay nodes in modern communication networks, integrate populationwide inputs, and enable robust noise filtering for efficient high-fidelity signaling.-Wilson, C., Saunter, C. D., Girkin, J. M., McCarron, J. G. Clusters of specialized detector cells provide sensitive and high fidelity receptor signaling in the intact endothelium. PMID:26873937

  6. Clusters of specialized detector cells provide sensitive and high fidelity receptor signaling in the intact endothelium

    PubMed Central

    Wilson, Calum; Saunter, Christopher D.; Girkin, John M.; McCarron, John G.

    2016-01-01

    Agonist-mediated signaling by the endothelium controls virtually all vascular functions. Because of the large diversity of agonists, each with varying concentrations, background noise often obscures individual cellular signals. How the endothelium distinguishes low-level fluctuations from noise and decodes and integrates physiologically relevant information remains unclear. Here, we recorded changes in intracellular Ca2+ concentrations in response to acetylcholine in areas encompassing hundreds of endothelial cells from inside intact pressurized arteries. Individual cells responded to acetylcholine with a concentration-dependent increase in Ca2+ signals spanning a single order of magnitude. Interestingly, however, intercellular response variation extended over 3 orders of magnitude of agonist concentration, thus crucially enhancing the collective bandwidth of endothelial responses to agonists. We also show the accuracy of this collective mode of detection is facilitated by spatially restricted clusters of comparably sensitive cells arising from heterogeneous receptor expression. Simultaneous stimulation of clusters triggered Ca2+ signals that were transmitted to neighboring cells in a manner that scaled with agonist concentration. Thus, the endothelium detects agonists by acting as a distributed sensing system. Specialized clusters of detector cells, analogous to relay nodes in modern communication networks, integrate populationwide inputs, and enable robust noise filtering for efficient high-fidelity signaling.—Wilson, C., Saunter, C. D., Girkin, J. M., McCarron, J. G. Clusters of specialized detector cells provide sensitive and high fidelity receptor signaling in the intact endothelium. PMID:26873937

  7. Preparation of Special Educators in Essential Early Education. Preparation of Personnel To Provide Special Education and Related Services to Newborn and Infant Children with Handicaps.

    ERIC Educational Resources Information Center

    Fox, Wayne; Capone, Angela

    The Preparation of Special Educators in Essential Early Education program was a 36-credit hour preservice program of the University of Vermont to train Early Childhood Special Educators at the Master's Degree or Certificate of Advanced Study levels. The program prepared students to demonstrate the necessary competencies for providing quality…

  8. Are Midwestern School Administrators Prepared to Provide Leadership in Special Education?

    ERIC Educational Resources Information Center

    Schaaf, Michael; Williamson, Robert; Novak, Jeanne

    2015-01-01

    School administrators set the tone for the implementation of special education within their schools. Researchers examined school administrators' perceptions of (a) how well their leadership preparation programs equipped them to administer special education programs and (b) special education topics about which they desired additional coursework.…

  9. Whole-genome sequencing of cultivated and wild peppers provides insights into Capsicum domestication and specialization

    PubMed Central

    Qin, Cheng; Yu, Changshui; Shen, Yaou; Fang, Xiaodong; Chen, Lang; Min, Jiumeng; Cheng, Jiaowen; Zhao, Shancen; Xu, Meng; Luo, Yong; Yang, Yulan; Wu, Zhiming; Mao, Likai; Wu, Haiyang; Ling-Hu, Changying; Zhou, Huangkai; Lin, Haijian; González-Morales, Sandra; Trejo-Saavedra, Diana L.; Tian, Hao; Tang, Xin; Zhao, Maojun; Huang, Zhiyong; Zhou, Anwei; Yao, Xiaoming; Cui, Junjie; Li, Wenqi; Chen, Zhe; Feng, Yongqiang; Niu, Yongchao; Bi, Shimin; Yang, Xiuwei; Li, Weipeng; Cai, Huimin; Luo, Xirong; Montes-Hernández, Salvador; Leyva-González, Marco A.; Xiong, Zhiqiang; He, Xiujing; Bai, Lijun; Tan, Shu; Tang, Xiangqun; Liu, Dan; Liu, Jinwen; Zhang, Shangxing; Chen, Maoshan; Zhang, Lu; Zhang, Li; Zhang, Yinchao; Liao, Weiqin; Zhang, Yan; Wang, Min; Lv, Xiaodan; Wen, Bo; Liu, Hongjun; Luan, Hemi; Zhang, Yonggang; Yang, Shuang; Wang, Xiaodian; Xu, Jiaohui; Li, Xueqin; Li, Shuaicheng; Wang, Junyi; Palloix, Alain; Bosland, Paul W.; Li, Yingrui; Krogh, Anders; Rivera-Bustamante, Rafael F.; Herrera-Estrella, Luis; Yin, Ye; Yu, Jiping; Hu, Kailin; Zhang, Zhiming

    2014-01-01

    As an economic crop, pepper satisfies people’s spicy taste and has medicinal uses worldwide. To gain a better understanding of Capsicum evolution, domestication, and specialization, we present here the genome sequence of the cultivated pepper Zunla-1 (C. annuum L.) and its wild progenitor Chiltepin (C. annuum var. glabriusculum). We estimate that the pepper genome expanded ∼0.3 Mya (with respect to the genome of other Solanaceae) by a rapid amplification of retrotransposons elements, resulting in a genome comprised of ∼81% repetitive sequences. Approximately 79% of 3.48-Gb scaffolds containing 34,476 protein-coding genes were anchored to chromosomes by a high-density genetic map. Comparison of cultivated and wild pepper genomes with 20 resequencing accessions revealed molecular footprints of artificial selection, providing us with a list of candidate domestication genes. We also found that dosage compensation effect of tandem duplication genes probably contributed to the pungent diversification in pepper. The Capsicum reference genome provides crucial information for the study of not only the evolution of the pepper genome but also, the Solanaceae family, and it will facilitate the establishment of more effective pepper breeding programs. PMID:24591624

  10. 14 CFR 382.31 - May carriers impose special charges on passengers with a disability for providing services and...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false May carriers impose special charges on passengers with a disability for providing services and accommodations required by this rule? 382.31 Section 382.31 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) SPECIAL REGULATIONS...

  11. Special Needs Conference: Providing Educational Opportunity for All People. (Flint, Michigan, October 16 and 17, 1975)

    ERIC Educational Resources Information Center

    1976

    This document summarizes the proceedings of a workshop dealing with the role of the community colleges in serving people with special needs--minorities, women, the physically handicapped, and the poor. It includes a topical speech by Dr. Reginald Wilson, president of Wayne County Community College, and another on support programs for special needs…

  12. School Transitions: A Qualitative Study of the Supports Provided by Washington State Special Education Administrators

    ERIC Educational Resources Information Center

    Lewinsohn, Kari

    2013-01-01

    This study investigated the role of special education administrators in the transition planning process for children with disabilities ages 3-21 in selected Washington school districts. A basic qualitative study was selected to construct meaning from a described phenomenon. The study sought to identify and explain how special education…

  13. Open and closed evolutionary paths for drastic morphological changes, involving serial gene duplication, sub-functionalization, and selection

    PubMed Central

    Abe, Gembu; Lee, Shu-Hua; Li, Ing-Jia; Chang, Chun-Ju; Tamura, Koji; Ota, Kinya G.

    2016-01-01

    Twin-tail goldfish strains are examples of drastic morphological alterations that emerged through domestication. Although this mutation is known to be caused by deficiency of one of two duplicated chordin genes, it is unknown why equivalent mutations have not been observed in other domesticated fish species. Here, we compared the chordin gene morphant phenotypes of single-tail goldfish and common carp (close relatives, both of which underwent chordin gene duplication and domestication). Morpholino-induced knockdown depleted chordin gene expression in both species; however, while knockdown reproduced twin-tail morphology in single-tail goldfish, it had no effect on common carp morphology. This difference can be explained by the observation that expression patterns of the duplicated chordin genes overlap completely in common carp, but are sub-functionalized in goldfish. Our finding implies that goldfish drastic morphological changes might be enhanced by the subsequent occurrence of three different types of evolutionary event (duplication, sub-functionalization, and selection) in a certain order. PMID:27220684

  14. Open and closed evolutionary paths for drastic morphological changes, involving serial gene duplication, sub-functionalization, and selection.

    PubMed

    Abe, Gembu; Lee, Shu-Hua; Li, Ing-Jia; Chang, Chun-Ju; Tamura, Koji; Ota, Kinya G

    2016-01-01

    Twin-tail goldfish strains are examples of drastic morphological alterations that emerged through domestication. Although this mutation is known to be caused by deficiency of one of two duplicated chordin genes, it is unknown why equivalent mutations have not been observed in other domesticated fish species. Here, we compared the chordin gene morphant phenotypes of single-tail goldfish and common carp (close relatives, both of which underwent chordin gene duplication and domestication). Morpholino-induced knockdown depleted chordin gene expression in both species; however, while knockdown reproduced twin-tail morphology in single-tail goldfish, it had no effect on common carp morphology. This difference can be explained by the observation that expression patterns of the duplicated chordin genes overlap completely in common carp, but are sub-functionalized in goldfish. Our finding implies that goldfish drastic morphological changes might be enhanced by the subsequent occurrence of three different types of evolutionary event (duplication, sub-functionalization, and selection) in a certain order. PMID:27220684

  15. [Housing and health: providing special aids to geriatric patients (rehabilitation in relation to section 46 BSHG)].

    PubMed

    Pöllen, W

    1991-01-01

    The age structure of the population is undergoing dramatic changes resulting in a steady increase in the number of geriatric patients requiring special care. In 2000 A.D. about one quarter of the inhabitants of North Rhine Westphalia will be over 60 years of age. In our Geriatric Advisory Service bureau the number of patients over 60 years of age has been rising steadily in recent years and is at present about 49.5% of a total of 2,069 patients who in 1990 are being looked after by our Advisory Office for the Elderly, the Sick and the Physically Handicapped in the North Rhine Westphalian capital city of Düsseldorf. One of the fundamental principles of our work is to check on the required measures of social rehabilitation in consultation with the physicians, physiotherapists, ergotherapists and the hospital social welfare service, so that the patient can be looked after at home without any break directly after his discharge from hospital. All the necessary auxiliaries such as handles fixed to the bath-room wall above the bathtub, bathtub seat, toilet chair etc. should be available when the patient moves into his or her home. This supply of auxiliary devices is very important because otherwise it will often not be possible to realize other tasks of social rehabilitation. For example, the patient can often not be provided at short notice with a flat that will be convenient for his disability, which means that fitting the auxiliary devices is the only way out of the problem to adapt the existing flat to his needs.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:1837907

  16. Providing Optimal Opportunities: Structuring Practicum Experiences in Early Intervention and Early Childhood Special Education Preservice Programs

    ERIC Educational Resources Information Center

    Macy, Marisa; Squires, Jane K.; Barton, Erin E.

    2009-01-01

    An approach to designing field-based practicum opportunities for preservice students is described. First, the importance of quality field experiences is presented, together with a conceptual framework. Second, foundational and philosophical perspectives in early childhood and early intervention (EI) and early childhood special education (ECSE)…

  17. Promising Practices in the Preparation of Special Educators to Provide Reading Instruction

    ERIC Educational Resources Information Center

    Sayeski, Kristin L.; Gormley Budin, Shannon E.; Bennett, Katie

    2015-01-01

    The majority of students with disabilities require support in the area of reading. Given the importance of reading instruction, it is essential that special education teacher preparation programs prepare candidates who are knowledgeable about reading development and skilled in the delivery of reading instruction. The purpose of this article is…

  18. Transition Planning for Adolescents with Special Health Care Needs and Disabilities: A Guide for Health Care Providers.

    ERIC Educational Resources Information Center

    Porter, Stephanie; Freeman, Linda; Griffin, Lynne Reeves

    Designed for Massachusetts health care providers, this booklet provides information on transition planning for adolescents with special health care needs and disabilities. It includes resources and strategies to guide interventions with families and to focus their attention on four key facets of adulthood: health care, education, employment, and…

  19. 48 CFR 1545.309 - Providing Government production and research property under special restrictions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Regulations System ENVIRONMENTAL PROTECTION AGENCY CONTRACT MANAGEMENT GOVERNMENT PROPERTY Providing Government Property to Contractors 1545.309 Providing Government production and research property under... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Providing...

  20. 48 CFR 1545.309 - Providing Government production and research property under special restrictions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Regulations System ENVIRONMENTAL PROTECTION AGENCY CONTRACT MANAGEMENT GOVERNMENT PROPERTY Providing Government Property to Contractors 1545.309 Providing Government production and research property under... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Providing...

  1. 48 CFR 1545.309 - Providing Government production and research property under special restrictions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Regulations System ENVIRONMENTAL PROTECTION AGENCY CONTRACT MANAGEMENT GOVERNMENT PROPERTY Providing Government Property to Contractors 1545.309 Providing Government production and research property under... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Providing...

  2. 48 CFR 1545.309 - Providing Government production and research property under special restrictions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Regulations System ENVIRONMENTAL PROTECTION AGENCY CONTRACT MANAGEMENT GOVERNMENT PROPERTY Providing Government Property to Contractors 1545.309 Providing Government production and research property under... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Providing...

  3. 41 CFR 102-41.150 - What special information do we provide on reports of unclaimed personal property?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... do we provide on reports of unclaimed personal property? 102-41.150 Section 102-41.150 Public... MANAGEMENT REGULATION PERSONAL PROPERTY 41-DISPOSITION OF SEIZED, FORFEITED, VOLUNTARILY ABANDONED, AND UNCLAIMED PERSONAL PROPERTY Unclaimed Personal Property § 102-41.150 What special information do we...

  4. 7 CFR 1822.278 - Special requirements for RHS section 523 loans (loans to organizations providing sites for self...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 12 2012-01-01 2012-01-01 false Special requirements for RHS section 523 loans (loans to organizations providing sites for self-help housing). 1822.278 Section 1822.278 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND...

  5. Educating Healthcare Providers Regarding LGBT Patients and Health Issues: The Special Case of Physician Assistants

    ERIC Educational Resources Information Center

    Compton, David A.; Whitehead, Michael B.

    2015-01-01

    Much is written about the availability of healthcare services among elements of the U.S. population, with a large proportion of the literature focusing on access. Although physical access is an overarching issue for many, educators must remember that a key factor in providing complete and competent healthcare is to understand the patient and any…

  6. Feeding Students in School: Providing Guidelines and Information on Safe Feeding Practices for Special Students.

    ERIC Educational Resources Information Center

    Hall, Sandra; And Others

    This manual provides guidelines for safe feeding practices for students with disabilities in Oregon schools. Stressed is the importance of distinguishing between feeding for the maintenance of health and feeding for the acquisition of skills. Individual sections cover: definitions of feeding programs; the school district responsibility; risks;…

  7. 42 CFR 422.214 - Special rules for services furnished by noncontract providers.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ....105(g) concerns indirect medical education payment to hospitals for managed care enrollees. Section 413.76 concerns calculating payment for direct medical education costs.) (c) Deemed request for... provider expressly notifies the MA organization in writing that it is billing an amount less than...

  8. Special Collections and the New Web: Using LibGuides to Provide Meaningful Access

    ERIC Educational Resources Information Center

    Lewis, Barbara; Griffin, Melanie

    2011-01-01

    Librarians have long struggled to find user-friendly mediums to provide meaningful information to patrons using bibliographies, pathfinders, and subject guides with varying degrees of success. Content management systems, such as Springshare's LibGuides, have recently been developed to facilitate the creation of online subject guides. Special…

  9. Implementing a care coordination program for children with special healthcare needs: partnering with families and providers.

    PubMed

    Taylor, April; Lizzi, Michele; Marx, Alison; Chilkatowsky, Maryann; Trachtenberg, Symme W; Ogle, Sue

    2013-01-01

    Care coordination has been a key theme in national forums on healthcare quality, design, and improvement. This article describes the characteristics of a care coordination program aimed at supporting families in building care coordination competencies and providers in the coordination of care across multiple specialties. The program included implementation of a Care Coordination Counselor (CC Counselor) and several supporting tools-Care Binders, Complex Scheduling, Community Resources for Families Database, and a Care Coordination Network. Patients were referred by a healthcare provider to receive services from the CC Counselor or to receive a Care Binder organizational tool. To assess the impact of the counselor role, we compared patient experience survey results from patients receiving CC Counselor services to those receiving only the Care Binder. Our analysis found that patients supported by the CC Counselor reported greater agreement with accessing care coordination resources and identifying a key point person for coordination. Seventy-five percent of CC Counselor patients have graduated from the program. Our findings suggest that implementation of a CC Counselor role and supporting tools offers an integrative way to connect patients, families, and providers with services and resources to support coordinated, continuous care. PMID:22913270

  10. Hinged plakin domains provide specialized degrees of articulation in envoplakin, periplakin and desmoplakin.

    PubMed

    Al-Jassar, Caezar; Bernadό, Pau; Chidgey, Martyn; Overduin, Michael

    2013-01-01

    Envoplakin, periplakin and desmoplakin are cytoskeletal proteins that provide structural integrity within the skin and heart by resisting shear forces. Here we reveal the nature of unique hinges within their plakin domains that provides divergent degrees of flexibility between rigid long and short arms composed of spectrin repeats. The range of mobility of the two arms about the hinge is revealed by applying the ensemble optimization method to small-angle X-ray scattering data. Envoplakin and periplakin adopt 'L' shaped conformations exhibiting a 'helicopter propeller'-like mobility about the hinge. By contrast desmoplakin exhibits essentially unrestricted mobility by 'jack-knifing' about the hinge. Thus the diversity of molecular jointing that can occur about plakin hinges includes 'L' shaped bends, 'U' turns and fully extended 'I' orientations between rigid blocks of spectrin repeats. This establishes specialised hinges in plakin domains as a key source of flexibility that may allow sweeping of cellular spaces during assembly of cellular structures and could impart adaptability, so preventing irreversible damage to desmosomes and the cell cytoskeleton upon exposure to mechanical stress. PMID:23922795

  11. Hydrophobic Core Variations Provide a Structural Framework for Tyrosine Kinase Evolution and Functional Specialization

    PubMed Central

    Kwon, Annie; Byrne, Dominic P.; Ferries, Samantha; Ruan, Zheng; Hanold, Laura E.; Katiyar, Samiksha; Kennedy, Eileen J.; Eyers, Patrick A.; Kannan, Natarajan

    2016-01-01

    Protein tyrosine kinases (PTKs) are a group of closely related enzymes that have evolutionarily diverged from serine/threonine kinases (STKs) to regulate pathways associated with multi-cellularity. Evolutionary divergence of PTKs from STKs has occurred through accumulation of mutations in the active site as well as in the commonly conserved hydrophobic core. While the functional significance of active site variations is well understood, relatively little is known about how hydrophobic core variations contribute to PTK evolutionary divergence. Here, using a combination of statistical sequence comparisons, molecular dynamics simulations, mutational analysis and in vitro thermostability and kinase assays, we investigate the structural and functional significance of key PTK-specific variations in the kinase core. We find that the nature of residues and interactions in the hydrophobic core of PTKs is strikingly different from other protein kinases, and PTK-specific variations in the core contribute to functional divergence by altering the stability and dynamics of the kinase domain. In particular, a functionally critical STK-conserved histidine that stabilizes the regulatory spine in STKs is selectively mutated to an alanine, serine or glutamate in PTKs, and this loss-of-function mutation is accommodated, in part, through compensatory PTK-specific interactions in the core. In particular, a PTK-conserved phenylalanine in the I-helix appears to structurally and functionally compensate for the loss of STK-histidine by interacting with the regulatory spine, which has far-reaching effects on enzyme activity, inhibitor sensing, and stability. We propose that hydrophobic core variations provide a selective advantage during PTK evolution by increasing the conformational flexibility, and therefore the allosteric potential of the kinase domain. Our studies also suggest that Tyrosine Kinase Like kinases such as RAF are intermediates in PTK evolutionary divergence inasmuch as they

  12. Specialization.

    ERIC Educational Resources Information Center

    Luna, Pat

    Designed for middle school students, this award winning, six-day teaching unit helped students learn about the concepts of specialization, interdependence, efficiency, and profit. At the onset of the lesson the students were already familiar with the concepts of scarcity, goods, services, profits, supply, demand, and opportunity costs. The unit's…

  13. Evidence that Osteoblasts are Specialized Citrate-producing Cells that Provide the Citrate for Incorporation into the Structure of Bone

    PubMed Central

    Franklin, Renty B.; Chellaiah, Meena; Zou, Jing; Reynolds, Mark A.; Costello, Leslie C.

    2015-01-01

    Citrate is a major component of bone in all vertebrates, but its implications in bone have remained largely unknown. Recent studies identified that citrate is incorporated into the structure of the hydroxyapatite nanocrystal/collagen complex; and is essential for the important biomechanical properties of bone. This raises the important question, “What is the source of citrate for incorporation into bone?”; A question that heretofore had remained unresolved. Studies in this report were designed to determine the plausibility of our concept that the osteoblasts are specialized citrate-producing cells, which provide the citrate that is incorporated into the structure of bone; and that osteogenic differentiation of mesenchyme cells leads to the development of the citrate-producing osteoblasts. The results demonstrated that primary human osteoblasts exhibit the capability of citrate-production. Undifferentiated mesenchyme cells do not exhibit the capability of citrate production; and osteogenic differentiation results in citrate-producing osteoblasts. The up-regulation of zinc uptake transporter ZIP1 is essential for the manifestation of the citrate-producing capability of the osteoblasts. We determined that osteoblast transport of citrate from plasma is not a likely source of citrate in bone. Thus, this study establishes for the first time that the osteoblasts are specialized citrate-producing cells that provide the citrate for incorporation into the structure of bone; and that mesenchyme cell osteogenesis leads to differentiated citrate-producing osteoblasts. This is a new understanding; which must include the osteogenic development of citrate-producing osteoblasts, and the process of “citration” in concert with mineralization during bone formation. It also provides a new understanding of the role of bone in the homeostatic maintenance of plasma citrate concentration. PMID:25745519

  14. 34 CFR 376.1 - What is the program of Special Projects and Demonstrations for Providing Transitional...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false What is the program of Special Projects and....1 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION SPECIAL PROJECTS AND DEMONSTRATIONS...

  15. Reaching across boundaries: a military providers and public schools partnership on behalf of children with special needs.

    PubMed

    Lewis-Fleming, Glenda

    2014-08-01

    In January 2011, Neurodevelopmental Pediatrics, a division of the Pediatric Department at Naval Medical Center Portsmouth established a collaborative effort with the local public school systems called the Community Partnership Forum. This performance improvement initiative was designed to strengthen community relationships and communication between Neurodevelopmental Pediatrics, the local public school systems, and diverse military and civilian agencies engaged in the education and care of military children with disabilities in Hampton Roads, Virginia. It was developed as a result of military families and providers voicing concerns about ongoing obstacles with special education-related services. The goal was to create a local multifaceted process to mitigate myths and promote a shared understanding of educational resources in the medical and educational systems. This article summarizes this collegial process between the medical center, the public school systems, and diverse military and community agencies. PMID:25102537

  16. Accelerated Gene Evolution and Subfunctionalization in thePseudotetraploid Frog Xenopus Laevis

    SciTech Connect

    Hellsten, Uffe; Khokha, Mustafa K.; Grammar, Timothy C.; Harland,Richard M.; Richardson, Paul; Rokhsar, Daniel S.

    2007-03-01

    Ancient whole genome duplications have been implicated in the vertebrate and teleost radiations, and in the emergence of diverse angiosperm lineages, but the evolutionary response to such a perturbation is still poorly understood. The African clawed frog Xenopus laevis experienced a relatively recent tetraploidization {approx} 40 million years ago. Analysis of the considerable amount of EST sequence available for this species together with the genome sequence of the related diploid Xenopus tropicalis provides a unique opportunity to study the genomic response to whole genome duplication.

  17. 34 CFR 380.1 - What is the program of special projects and demonstrations for providing supported employment...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false What is the program of special projects and... technical assistance projects? 380.1 Section 380.1 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF...

  18. 14 CFR 382.31 - May carriers impose special charges on passengers with a disability for providing services and...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false May carriers impose special charges on... 382.31 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) SPECIAL REGULATIONS NONDISCRIMINATION ON THE BASIS OF DISABILITY IN AIR TRAVEL...

  19. 14 CFR 382.31 - May carriers impose special charges on passengers with a disability for providing services and...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false May carriers impose special charges on... 382.31 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) SPECIAL REGULATIONS NONDISCRIMINATION ON THE BASIS OF DISABILITY IN AIR TRAVEL...

  20. 14 CFR 382.31 - May carriers impose special charges on passengers with a disability for providing services and...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false May carriers impose special charges on... 382.31 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) SPECIAL REGULATIONS NONDISCRIMINATION ON THE BASIS OF DISABILITY IN AIR TRAVEL...

  1. 14 CFR 382.31 - May carriers impose special charges on passengers with a disability for providing services and...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false May carriers impose special charges on... 382.31 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) SPECIAL REGULATIONS NONDISCRIMINATION ON THE BASIS OF DISABILITY IN AIR TRAVEL...

  2. An Issue Hiding in Plain Sight: When Are Speech-Language Pathologists Special Educators Rather than Related Services Providers?

    ERIC Educational Resources Information Center

    Giangreco, Michael F.; Prelock, Patricia A.; Turnbull, H. Rutherford, III

    2010-01-01

    Purpose: Under the Individuals With Disabilities Education Act (IDEA; as amended, 2004), speech-language pathology services may be either special education or a related service. Given the absence of guidance documents or research on this issue, the purposes of this clinical exchange are to (a) present and analyze the IDEA definitions related to…

  3. Did Androgen-Binding Protein Paralogs Undergo Neo- and/or Subfunctionalization as the Abp Gene Region Expanded in the Mouse Genome?

    PubMed Central

    Karn, Robert C.; Chung, Amanda G.; Laukaitis, Christina M.

    2014-01-01

    The Androgen-binding protein (Abp) region of the mouse genome contains 30 Abpa genes encoding alpha subunits and 34 Abpbg genes encoding betagamma subunits, their products forming dimers composed of an alpha and a betagamma subunit. We endeavored to determine how many Abp genes are expressed as proteins in tears and saliva, and as transcripts in the exocrine glands producing them. Using standard PCR, we amplified Abp transcripts from cDNA libraries of C57BL/6 mice and found fifteen Abp gene transcripts in the lacrimal gland and five in the submandibular gland. Proteomic analyses identified proteins corresponding to eleven of the lacrimal gland transcripts, all of them different from the three salivary ABPs reported previously. Our qPCR results showed that five of the six transcripts that lacked corresponding proteins are expressed at very low levels compared to those transcripts with proteins. We found 1) no overlap in the repertoires of expressed Abp paralogs in lacrimal gland/tears and salivary glands/saliva; 2) substantial sex-limited expression of lacrimal gland/tear expressed-paralogs in males but no sex-limited expression in females; and 3) that the lacrimal gland/tear expressed-paralogs are found exclusively in ancestral clades 1, 2 and 3 of the five clades described previously while the salivary glands/saliva expressed-paralogs are found only in clade 5. The number of instances of extremely low levels of transcription without corresponding protein production in paralogs specific to tears and saliva suggested the role of subfunctionalization, a derived condition wherein genes that may have been expressed highly in both glands ancestrally were down-regulated subsequent to duplication. Thus, evidence for subfunctionalization can be seen in our data and we argue that the partitioning of paralog expression between lacrimal and salivary glands that we report here occurred as the result of adaptive evolution. PMID:25531410

  4. The Special Needs Program for Inmate-Patients with Dementia (SNPID): a psychosocial program provided in the prison system.

    PubMed

    Hodel, Bettina; Sánchez, Heriberto G

    2013-09-01

    This article discusses a comprehensive psychosocial program developed for a prison in California--the Special Needs Program for Inmate-Patients with Dementia (SNPID). It describes the individual steps of the program, their content and their application in a system that has safety and security as its highest priority. An important and innovatory aspect of SNIPD is the role of other inmates in supporting inmates with dementia. The article concludes that psychosocial interventions can be appropriately applied in prison settings and make a difference in the quality of life for inmate-patients with dementia. PMID:24337336

  5. 34 CFR 376.1 - What is the program of Special Projects and Demonstrations for Providing Transitional...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Demonstrations for Providing Transitional Rehabilitation Services to Youths with Disabilities? 376.1 Section 376... PROVIDING TRANSITIONAL REHABILITATION SERVICES TO YOUTH WITH DISABILITIES General § 376.1 What is the... Youths with Disabilities? This program is designed to provide job training for youths with...

  6. 34 CFR 376.1 - What is the program of Special Projects and Demonstrations for Providing Transitional...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Demonstrations for Providing Transitional Rehabilitation Services to Youths with Disabilities? 376.1 Section 376... PROVIDING TRANSITIONAL REHABILITATION SERVICES TO YOUTH WITH DISABILITIES General § 376.1 What is the... Youths with Disabilities? This program is designed to provide job training for youths with...

  7. 34 CFR 376.1 - What is the program of Special Projects and Demonstrations for Providing Transitional...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Demonstrations for Providing Transitional Rehabilitation Services to Youths with Disabilities? 376.1 Section 376... PROVIDING TRANSITIONAL REHABILITATION SERVICES TO YOUTH WITH DISABILITIES General § 376.1 What is the... Youths with Disabilities? This program is designed to provide job training for youths with...

  8. 34 CFR 376.1 - What is the program of Special Projects and Demonstrations for Providing Transitional...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Demonstrations for Providing Transitional Rehabilitation Services to Youths with Disabilities? 376.1 Section 376... PROVIDING TRANSITIONAL REHABILITATION SERVICES TO YOUTH WITH DISABILITIES General § 376.1 What is the... Youths with Disabilities? This program is designed to provide job training for youths with...

  9. The Profiling System/Using Psychological Type and Learning Style To Provide Adaptations for Teaching Methodology in the Regular and Special Education Classroom.

    ERIC Educational Resources Information Center

    Waters, Gisele A.; Lasage, Ed.

    The purpose of the Profiling System is to provide diagnostic and instructional resources to regular and special education teachers. The Profiling System is based on research and literature in psychological type and learning style. It combines the literature in these areas with academic and perceptual assessment instruments to screen for learning…

  10. 42 CFR 482.58 - Special requirements for hospital providers of long-term care services (“swing-beds”).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...-term care services (âswing-bedsâ). 482.58 Section 482.58 Public Health CENTERS FOR MEDICARE & MEDICAID... long-term care services (“swing-beds”). A hospital that has a Medicare provider agreement must meet the following requirements in order to be granted an approval from CMS to provide post-hospital extended...

  11. 42 CFR 482.66 - Special requirements for hospital providers of long-term care services (“swing-beds”).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...-term care services (âswing-bedsâ). 482.66 Section 482.66 Public Health CENTERS FOR MEDICARE & MEDICAID... providers of long-term care services (“swing-beds”). A hospital that has a Medicare provider agreement must... extended care services, as specified in § 409.30 of this chapter, and be reimbursed as a swing-bed...

  12. 42 CFR 482.66 - Special requirements for hospital providers of long-term care services (“swing-beds”).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...-term care services (âswing-bedsâ). 482.66 Section 482.66 Public Health CENTERS FOR MEDICARE & MEDICAID... providers of long-term care services (“swing-beds”). A hospital that has a Medicare provider agreement must... extended care services, as specified in § 409.30 of this chapter, and be reimbursed as a swing-bed...

  13. 42 CFR 482.66 - Special requirements for hospital providers of long-term care services (“swing-beds”).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...-term care services (âswing-bedsâ). 482.66 Section 482.66 Public Health CENTERS FOR MEDICARE & MEDICAID... providers of long-term care services (“swing-beds”). A hospital that has a Medicare provider agreement must... extended care services, as specified in § 409.30 of this chapter, and be reimbursed as a swing-bed...

  14. Special Education in the Natural Environment: A Resource Guide in Providing Outdoor Education, Recreation and Camping for Children with Disabilities.

    ERIC Educational Resources Information Center

    Robb, Gary M.; And Others

    The resource guide for use with personnel concerned with outdoor education for handicapped children provides a guide to activities, techniques, resources, and equipment. The first section consists of analyzed activities as they relate to individual education plans and treatment plan objectives. Provided for each activity is a description of the…

  15. 7 CFR 1822.278 - Special requirements for RHS section 523 loans (loans to organizations providing sites for self...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... to organizations providing sites for self-help housing). 1822.278 Section 1822.278 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE... PRIMARILY FOR REAL ESTATE PURPOSES RURAL HOUSING LOANS AND GRANTS Rural Housing Site Loan...

  16. 7 CFR 1822.278 - Special requirements for RHS section 523 loans (loans to organizations providing sites for self...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... to organizations providing sites for self-help housing). 1822.278 Section 1822.278 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE... PRIMARILY FOR REAL ESTATE PURPOSES RURAL HOUSING LOANS AND GRANTS Rural Housing Site Loan...

  17. 42 CFR 485.645 - Special requirements for CAH providers of long-term care services (“swing-beds”)

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... following requirements in order to be granted an approval from CMS to provided post-hospital SNF care, as specified in § 409.30 of this chapter, and to be paid for SNF-level services, in accordance with paragraph...-part SNF at the time the facility applies to the State for designation as a CAH is not counted...

  18. 42 CFR 485.645 - Special requirements for CAH providers of long-term care services (“swing-beds”)

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... following requirements in order to be granted an approval from CMS to provided post-hospital SNF care, as specified in § 409.30 of this chapter, and to be paid for SNF-level services, in accordance with paragraph...-part SNF at the time the facility applies to the State for designation as a CAH is not counted...

  19. 42 CFR 485.645 - Special requirements for CAH providers of long-term care services (“swing-beds”)

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... following requirements in order to be granted an approval from CMS to provided post-hospital SNF care, as specified in § 409.30 of this chapter, and to be paid for SNF-level services, in accordance with paragraph...-part SNF at the time the facility applies to the State for designation as a CAH is not counted...

  20. 42 CFR 485.645 - Special requirements for CAH providers of long-term care services (“swing-beds”)

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... following requirements in order to be granted an approval from CMS to provided post-hospital SNF care, as specified in § 409.30 of this chapter, and to be paid for SNF-level services, in accordance with paragraph...-part SNF at the time the facility applies to the State for designation as a CAH is not counted...

  1. 42 CFR 485.645 - Special requirements for CAH providers of long-term care services (“swing-beds”)

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... following requirements in order to be granted an approval from CMS to provided post-hospital SNF care, as specified in § 409.30 of this chapter, and to be paid for SNF-level services, in accordance with paragraph...-part SNF at the time the facility applies to the State for designation as a CAH is not counted...

  2. Subfunctionalization of Sigma Factors during the Evolution of Land Plants Based on Mutant Analysis of Liverwort (Marchantia polymorpha L.) MpSIG1

    PubMed Central

    Ueda, Minoru; Takami, Tsuneaki; Peng, Lianwei; Ishizaki, Kimitsune; Kohchi, Takayuki; Shikanai, Toshiharu; Nishimura, Yoshiki

    2013-01-01

    Sigma factor is a subunit of plastid-encoded RNA polymerase that regulates the transcription of plastid-encoded genes by recognizing a set of promoters. Sigma factors have increased in copy number and have diversified during the evolution of land plants, but details of this process remain unknown. Liverworts represent the basal group of embryophytes and are expected to retain the ancestral features of land plants. In liverwort (Marchantia polymorpha L.), we isolated and characterized a T-DNA-tagged mutant (Mpsig1) of sigma factor 1 (MpSIG1). The mutant did not show any visible phenotypes, implying that MpSIG1 function is redundant with that of other sigma factors. However, quantitative reverse-transcription polymerase chain reaction and RNA gel blot analysis revealed that genes related to photosynthesis were downregulated, resulting in the minor reduction of some protein complexes. The transcript levels of genes clustered in the petL, psaA, psbB, psbK, and psbE operons of liverwort were lower than those in the wild type, a result similar to that in the SIG1 defective mutant in rice (Oryza sativa). Overexpression analysis revealed primitive functional divergence between the SIG1 and SIG2 proteins in bryophytes, whereas these proteins still retain functional redundancy. We also discovered that the predominant sigma factor for ndhF mRNA expression has been diversified in liverwort, Arabidopsis (Arabidopsis thaliana), and rice. Our study shows the ancestral function of SIG1 and the process of functional partitioning (subfunctionalization) of sigma factors during the evolution of land plants. PMID:24025801

  3. An Analysis of Reading Skills Instruction Provided to Special and General Educators in Their Pre-Service and In-Service Teacher Education

    ERIC Educational Resources Information Center

    Castillo, Wendie Lappin

    2013-01-01

    More than half of all school-age children in the United States read below grade level (NCES, 2012a). Seventy-five percent of all special education referrals are due to poor reading skills (NCES, 2012b). The Office of Special Education and Rehabilitation Services reports that 50% or more of students with disabilities score at or below the 20th…

  4. Family perceptions of shared decision-making with health care providers: results of the National Survey of Children With Special Health Care Needs, 2009-2010.

    PubMed

    Smalley, LaQuanta P; Kenney, Mary Kay; Denboba, Diana; Strickland, Bonnie

    2014-08-01

    The Maternal and Child Health Bureau recently revised its measure of family-provider shared decision-making (SDM) to better align with parents' views and the intent of SDM. We sought to assess achievements in meeting the revised measure; examine socio-demographic/health correlates; and determine the relationships between SDM and access to quality health care. We analyzed data for 40,242 children with special health care needs (CSHCN) from the 2009-2010 National Survey of CSHCN and assessed the prevalence of SDM and association with other US CSHCN socio-demographic/health characteristics using bivariate and multivariate methods. Logistic regression was used to determine associations between SDM and having a medical home and preventive medical/dental visits. Approximately 70% of families of CSHCN perceived themselves as shared decision-makers in their child's care. Families of CSHCN with greater functional limitations had twice the odds of lacking SDM than those never affected. Disparities in attainment rates were noted for families with low versus high income (61 vs. 77%), less versus more than high school education (59 vs. 73%), privately insured versus uninsured (76 vs. 57%), and minority versus white race (63 vs. 74%). CSHCN with medical homes had 6 times greater odds of perceived SDM and as much as one and a half times the odds of receiving preventive care than CSHCN without a medical home. Major differences in family SDM perceptions are associated with having a medical home, particularly when characterized by family-centered care. Populations of concern are those with more functionally limited children and increased socio-economic challenges. PMID:24052119

  5. Can You Hear Me Now? Evaluation of an Online Wireless Technology to Provide Real-Time Feedback to Special Education Teachers-in-Training

    ERIC Educational Resources Information Center

    Rock, Marcia L.; Gregg, Madeleine; Thead, Beth K.; Acker, Sarah E.; Gable, Robert A.; Zigmond, Naomi P.

    2009-01-01

    In this study, the authors examine whether an advanced online technology can be used to give teacher trainees real-time feedback on their use of research-based classroom practices. Participants include 15 teachers enrolled in a field-based graduate special education teacher preparation program. Data include video-recorded teacher observations and…

  6. Cuidado de ninos con necesidades especiales en el hogar: Manual de referencia para las personas que cuidan ninos en sus hogares (Children with Special Needs in Family Day Care Homes: A Handbook for Family Day Care Home Providers).

    ERIC Educational Resources Information Center

    de la Brosse, Beatrice

    The Spanish translation of this guide offers information to Spanish-speaking family day care providers who desire to expand their knowledge of early childhood development in order to work with infants and young children with special needs in their day care settings. The first of four chapters answers common questions and concerns of day care…

  7. The return of the heart hospital. A hospital that specializes in providing cardiovascular services can meet community needs but will compete with existing community hospitals for market share.

    PubMed

    Smith, Robert B

    2002-10-01

    A hospital that provides cardiovascular services and embraces a heart-hospital brand and strategy can achieve competitive advantage. Providers that want to compete aggressively for cardiovascular services are developing a specialty-based carve-out strategy. A heart-hospital initiative can cannibalize revenues from a hospital's other programs and services. A successful heart-hospital strategy requires physician buy-in. A heart hospital needs a brand that customers will value. PMID:12373959

  8. Augmentation of special-needs services and information to students and teachers "ASSIST"--a telehealth innovation providing school-based medical interventions.

    PubMed

    Gallagher, Thomas E

    2004-10-01

    An innovative school-based telehealth technology was introduced in Hawaii with the purposes of: (1) evaluating students for medical/developmental conditions with educational implications, (2) providing a professionally-monitored Internet-based system of learning/development, and (3) delivering medically-based physical and occupational therapy at the students school. Electronically recorded satisfaction surveys from parents, teachers, and providers revealed significant improvement in all three areas. PMID:15570717

  9. 41 CFR 302-3.308 - Do I have to provide my agency with any special documents before receiving reimbursement for...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 4 2011-07-01 2011-07-01 false Do I have to provide my... 302-3.308 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RELOCATION ALLOWANCES 3-RELOCATION ALLOWANCE BY SPECIFIC TYPE Relocation Separation Ses...

  10. 41 CFR 302-3.308 - Do I have to provide my agency with any special documents before receiving reimbursement for...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false Do I have to provide my... 302-3.308 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RELOCATION ALLOWANCES 3-RELOCATION ALLOWANCE BY SPECIFIC TYPE Relocation Separation Ses...

  11. Tissue- and Cell-Type Specific Transcriptome Profiling of Expanding Tomato Fruit Provides Insights into Metabolic and Regulatory Specialization and Cuticle Formation[W][OA

    PubMed Central

    Matas, Antonio J.; Yeats, Trevor H.; Buda, Gregory J.; Zheng, Yi; Chatterjee, Subhasish; Tohge, Takayuki; Ponnala, Lalit; Adato, Avital; Aharoni, Asaph; Stark, Ruth; Fernie, Alisdair R.; Fei, Zhangjun; Giovannoni, James J.; Rose, Jocelyn K.C.

    2011-01-01

    Tomato (Solanum lycopersicum) is the primary model for the study of fleshy fruits, and research in this species has elucidated many aspects of fruit physiology, development, and metabolism. However, most of these studies have involved homogenization of the fruit pericarp, with its many constituent cell types. Here, we describe the coupling of pyrosequencing technology with laser capture microdissection to characterize the transcriptomes of the five principal tissues of the pericarp from tomato fruits (outer and inner epidermal layers, collenchyma, parenchyma, and vascular tissues) at their maximal growth phase. A total of 20,976 high-quality expressed unigenes were identified, of which more than half were ubiquitous in their expression, while others were cell type specific or showed distinct expression patterns in specific tissues. The data provide new insights into the spatial distribution of many classes of regulatory and structural genes, including those involved in energy metabolism, source-sink relationships, secondary metabolite production, cell wall biology, and cuticle biogenesis. Finally, patterns of similar gene expression between tissues led to the characterization of a cuticle on the inner surface of the pericarp, demonstrating the utility of this approach as a platform for biological discovery. PMID:22045915

  12. Foreword to Special Issue: Papers from the 54th Annual Meeting of the APS Division of Plasma Physics, Providence, Rhode Island, USA, 2012

    SciTech Connect

    Skiff, Fred; Davidson, Ronald C.

    2013-05-15

    Each year, the annual meeting of the APS Division of Plasma Physics (DPP) brings together a broad representation of the many active subfields of plasma physics and enjoys an audience that is equally diverse. The meeting was well attended and largely went as planned despite the interventions of hurricane Sandy which caused the city of Providence to shut-down during the first day of the conference. The meeting began on Monday morning with a review of the physics of cosmic rays, 2012 being the 100th year since their discovery, which illustrated the central importance of plasma physics to astrophysical problems. Subsequent reviews covered the importance of tokamak plasma boundaries, progress towards ignition on the National Ignition Facility (NIF), and magnetized plasma turbulence. The Maxwell prize address, by Professor Liu Chen, covered the field of nonlinear Alfvén wave physics. Tutorial lectures were presented on the verification of gyrokinetics, new capabilities in laboratory astrophysics, magnetic flux compression, and tokamak plasma start-up.

  13. Foreword to Special Issue: Papers from the 54th Annual Meeting of the APS Division of Plasma Physics, Providence, Rhode Island, USA, 2012

    NASA Astrophysics Data System (ADS)

    Skiff, Fred; Davidson, Ronald C.

    2013-05-01

    Each year, the annual meeting of the APS Division of Plasma Physics (DPP) brings together a broad representation of the many active subfields of plasma physics and enjoys an audience that is equally diverse. The meeting was well attended and largely went as planned despite the interventions of hurricane Sandy which caused the city of Providence to shut-down during the first day of the conference. The meeting began on Monday morning with a review of the physics of cosmic rays, 2012 being the 100th year since their discovery, which illustrated the central importance of plasma physics to astrophysical problems. Subsequent reviews covered the importance of tokamak plasma boundaries, progress towards ignition on the National Ignition Facility (NIF), and magnetized plasma turbulence. The Maxwell prize address, by Professor Liu Chen, covered the field of nonlinear Alfvén wave physics. Tutorial lectures were presented on the verification of gyrokinetics, new capabilities in laboratory astrophysics, magnetic flux compression, and tokamak plasma start-up.

  14. Providing Support for Families in Special Circumstances.

    ERIC Educational Resources Information Center

    Goetz, Kathy, Ed.

    1992-01-01

    This newsletter issue focuses on collaborating and coordinating services to assist families in stressful situations such as being afflicted with AIDS, being homeless, and experiencing intervention from child protection authorities. The newsletter includes the following articles: (1) "Finding Sources of Public Funding for Your Family Resource…

  15. Choosing Your Prenatal Care Provider

    MedlinePlus

    ... also called OB) is a doctor who has special education and training to take care of pregnant women ... midwife is a health care provider who has special education and training to take care of women of ...

  16. Mississippi Special Olympics: Special Events Manual.

    ERIC Educational Resources Information Center

    Heinze, Toni; Cooper, Walter E.

    Provided in the manual are organizational guidelines and suggested activities for a Special Evants segment of the Mississippi Special Olympics Program to encourage participation by low motor functioning, multihandicapped, mentally retarded persons. Information is provided concerning objectives, organizational set-up, guidelines, communication…

  17. SPECIAL CLASSES FOR STUDENTS WITH SPECIAL NEEDS.

    ERIC Educational Resources Information Center

    DOWELL, G.L.

    A SPECIAL 3-YEAR TRAINING PROGRAM IN FARM POWER AND MACHINERY WAS DEVELOPED TO PROVIDE FOR DIFFERENT LEVELS OF STUDENT ACHIEVEMENT AND TO HELP MEET THE NEED FOR SKILLED WORKERS IN THE MISSISSIPPI DELTA AREA. CHANGES IN THE LEARNING ENVIRONMENT OF STUDENTS TRANSFERRED FROM REGULAR VOCATIONAL AGRICULTURE CLASSES TO THE SPECIAL CLASSES PROVIDE A MORE…

  18. Special Days, Special Ways.

    ERIC Educational Resources Information Center

    Clarke, Jacqueline

    2001-01-01

    Presents unique ways to create special rituals that recognize individual students' achievements and milestones. Ideas include throwing a send-off party for a student who is moving; holding monthly birthday luncheons; choosing an ambassador to accompany new students around school; and making a lost tooth container that students can use to safely…

  19. The Atlantic salmon genome provides insights into rediploidization.

    PubMed

    Lien, Sigbjørn; Koop, Ben F; Sandve, Simen R; Miller, Jason R; Kent, Matthew P; Nome, Torfinn; Hvidsten, Torgeir R; Leong, Jong S; Minkley, David R; Zimin, Aleksey; Grammes, Fabian; Grove, Harald; Gjuvsland, Arne; Walenz, Brian; Hermansen, Russell A; von Schalburg, Kris; Rondeau, Eric B; Di Genova, Alex; Samy, Jeevan K A; Olav Vik, Jon; Vigeland, Magnus D; Caler, Lis; Grimholt, Unni; Jentoft, Sissel; Våge, Dag Inge; de Jong, Pieter; Moen, Thomas; Baranski, Matthew; Palti, Yniv; Smith, Douglas R; Yorke, James A; Nederbragt, Alexander J; Tooming-Klunderud, Ave; Jakobsen, Kjetill S; Jiang, Xuanting; Fan, Dingding; Hu, Yan; Liberles, David A; Vidal, Rodrigo; Iturra, Patricia; Jones, Steven J M; Jonassen, Inge; Maass, Alejandro; Omholt, Stig W; Davidson, William S

    2016-05-12

    The whole-genome duplication 80 million years ago of the common ancestor of salmonids (salmonid-specific fourth vertebrate whole-genome duplication, Ss4R) provides unique opportunities to learn about the evolutionary fate of a duplicated vertebrate genome in 70 extant lineages. Here we present a high-quality genome assembly for Atlantic salmon (Salmo salar), and show that large genomic reorganizations, coinciding with bursts of transposon-mediated repeat expansions, were crucial for the post-Ss4R rediploidization process. Comparisons of duplicate gene expression patterns across a wide range of tissues with orthologous genes from a pre-Ss4R outgroup unexpectedly demonstrate far more instances of neofunctionalization than subfunctionalization. Surprisingly, we find that genes that were retained as duplicates after the teleost-specific whole-genome duplication 320 million years ago were not more likely to be retained after the Ss4R, and that the duplicate retention was not influenced to a great extent by the nature of the predicted protein interactions of the gene products. Finally, we demonstrate that the Atlantic salmon assembly can serve as a reference sequence for the study of other salmonids for a range of purposes. PMID:27088604

  20. Special Education in Jordan

    ERIC Educational Resources Information Center

    Abu-Hamour, Bashir; Al-Hmouz, Hanan

    2014-01-01

    The purpose of this article is to provide a brief background about special education system in Jordan and particularly describes the present types of programmes and legislation provided within the country to students with special needs, as well as integration movement. Jordan has historically provided a limited number of educational opportunities…

  1. Demystifying Special Education in Virtual Charter Schools. Special Report. Primers on Special Education in Charter Schools

    ERIC Educational Resources Information Center

    Rhim, Lauren Morando; Kowal, Julie

    2008-01-01

    This special report is a supplement to a series of special education primers created to inform state officials, authorizers and charter school operators about special education in the charter sector. The primer series also provides tools to help these stakeholders build charter school capacity to provide special education and related services. In…

  2. Manual for Special Education Nurses.

    ERIC Educational Resources Information Center

    Schnetter, Vicki A., Ed.

    This manual aims (1) to provide a standard, well-referenced resource for Iowa special education nurses and (2) to provide direction and continuity for health services to pupils with special needs. The first chapter provides an overview of the special education nurse's role, including philosophy, definitions of assignments, levels of service, and…

  3. Providers issue brief: alternative providers.

    PubMed

    Rothouse, M

    1999-06-29

    Access by managed care plan enrollees, scope of practice issues and fee reimbursement by Medicaid and third parties such as insurance carriers is the engine that drives legislation recognizing alternative health care providers--chiropractors, acupuncturists, physical therapists, naturopaths, massage therapists, homeopaths, and dietitians and nutritionists. PMID:11073386

  4. Special Education Resource System.

    ERIC Educational Resources Information Center

    Kampert, George J.

    The guide to the Special Education Resource System (SERS) of the Flour Bluff (Texas) school system contains policies and procedures regarding organization, services, and process of the system. Noted is the SERS purpose of providing information and access to appropriate instructional media and materials for special education personnel. Briefly…

  5. A Very Special Education

    ERIC Educational Resources Information Center

    Jones, Hilda B.

    1973-01-01

    Granite School District, a suburb of Salt Lake City, Utah, has a staff of 349 teachers and other professional personnel who provide career education and job experience for more than 5,000 special children. (DS)

  6. Special Needs.

    ERIC Educational Resources Information Center

    Braswell, Ray, Ed.

    This document contains the following papers on special needs instruction and technology: (1) "Hawaii Special Education Teacher Induction" (Kalena Oliva and Quinn Avery); (2) "The Impact of Group v Individual Use of Hypermedia-Based Instruction" (Lewis R. Johnson, Louis P. Semrau, and Gail E. Fitzgerald); (3) "Assistive Technology Meets…

  7. Specialized Science

    PubMed Central

    Fang, Ferric C.

    2014-01-01

    As the body of scientific knowledge in a discipline increases, there is pressure for specialization. Fields spawn subfields that then become entities in themselves that promote further specialization. The process by which scientists join specialized groups has remarkable similarities to the guild system of the middle ages. The advantages of specialization of science include efficiency, the establishment of normative standards, and the potential for greater rigor in experimental research. However, specialization also carries risks of monopoly, monotony, and isolation. The current tendency to judge scientific work by the impact factor of the journal in which it is published may have roots in overspecialization, as scientists are less able to critically evaluate work outside their field than before. Scientists in particular define themselves through group identity and adopt practices that conform to the expectations and dynamics of such groups. As part of our continuing analysis of issues confronting contemporary science, we analyze the emergence and consequences of specialization in science, with a particular emphasis on microbiology, a field highly vulnerable to balkanization along microbial phylogenetic boundaries, and suggest that specialization carries significant costs. We propose measures to mitigate the detrimental effects of scientific specialism. PMID:24421049

  8. H.R. 2339: A Bill to amend the Agricultural Act of 1949 to permit producers to adopt integrated, site-specific farm management plans that provide for resource-conserving crop rotation, special conservation practices, rotational grazing, and biomass production operations and practices. Introduced in the House of Representatives, One Hundred Fourth Congress, First session

    SciTech Connect

    1995-12-31

    This document contains H.R. 2339, A Bill to amend the Agricultural Act of 1949 to permit producers to adopt integrated, site-specific farm management plans that provide for resource-conserving crop rotation, special conservation practices, rotational grazing, and biomass production operations and practices. This Bill was introduced in the House of Representatives, 104th Congress, First Session, September 14, 1995.

  9. Special Libraries

    ERIC Educational Resources Information Center

    Lavendel, Giuliana

    1977-01-01

    Discusses problems involved in maintaining special scientific or engineering libraries, including budget problems, remote storage locations, rental computer retrieval systems, protecting trade secrets, and establishing a magnetic tape library. (MLH)

  10. Special Delivery.

    ERIC Educational Resources Information Center

    Zimmer, Phil

    1986-01-01

    Specialized publications such as "Opera News,""Gourmet," and "Forbes" can bring an institution's story to targeted audiences. The experiences of Chautauqua Institution are described. Some of the benefits of marketing articles to these publications are discussed. (MLW)

  11. Ohio Special Education Profile, 2011

    ERIC Educational Resources Information Center

    Ohio Coalition for the Education of Children with Disabilities, 2011

    2011-01-01

    This report provides a brief, but substantive, profile of the special needs student population in Ohio, including academic performance and graduation trends and an overview of special education funding and related policy issues. The report's central message is that investments in students with special educational needs produce substantial results…

  12. Wrist ROM and Motion Frequency during Toy and Game Play with a Joint-Specific Controller Specially Designed to Provide Neuromuscular Therapy: A proof of concept study in typically developing children

    PubMed Central

    Crisco, Joseph J.; Schwartz, Joel B.; Wilcox, Bethany; Brideau, Holly; Basseches, Benjamin; Kerman, Karen

    2015-01-01

    Upper extremities affected by hemiplegic cerebral palsy (CP) and other neuromuscular disorders have been demonstrated to benefit from therapy, and the greater the duration of the therapy, the greater the benefit. A great motivator for participating in and extending the duration of therapy with children is play. Our focus is on active motion therapy of the wrist and forearm. In this study we examine the wrist motions associated with playing with two toys and three computer games controlled by a specially-designed play controller. Twenty children (ages 5-11) with no diagnosis of a muscular disorder were recruited. The play controller was fitted to the wrist and forearm of each child and used to measure and log wrist flexion and extension. Play activity and enjoyment were quantified by average wrist range of motion (ROM), motion frequency measures, and a discrete visual scale. We found significant differences in the average wrist ROM and motion frequency among the toys and games, yet there were no differences in the level of enjoyment across all toys and games, which was high. These findings indicate which toys and games may elicit the greater number of goal-directed movements, and lay the foundation for our long-term goal to develop and evaluate innovative motion-specific play controllers that are engaging rehabilitative devices for enhancing therapy and promoting neural plasticity and functional recovery in children with CP. PMID:25935686

  13. Wrist range of motion and motion frequency during toy and game play with a joint-specific controller specially designed to provide neuromuscular therapy: A proof of concept study in typically developing children.

    PubMed

    Crisco, Joseph J; Schwartz, Joel B; Wilcox, Bethany; Brideau, Holly; Basseches, Benjamin; Kerman, Karen

    2015-08-20

    Upper extremities affected by hemiplegic cerebral palsy (CP) and other neuromuscular disorders have been demonstrated to benefit from therapy, and the greater the duration of the therapy, the greater the benefit. A great motivator for participating in and extending the duration of therapy with children is play. Our focus is on active motion therapy of the wrist and forearm. In this study we examine the wrist motions associated with playing with two toys and three computer games controlled by a specially-designed play controller. Twenty children (ages 5-11) with no diagnosis of a muscular disorder were recruited. The play controller was fitted to the wrist and forearm of each child and used to measure and log wrist flexion and extension. Play activity and enjoyment were quantified by average wrist range of motion (ROM), motion frequency measures, and a discrete visual scale. We found significant differences in the average wrist ROM and motion frequency among the toys and games, yet there were no differences in the level of enjoyment across all toys and games, which was high. These findings indicate which toys and games may elicit the greater number of goal-directed movements, and lay the foundation for our long-term goal to develop and evaluate innovative motion-specific play controllers that are engaging rehabilitative devices for enhancing therapy and promoting neural plasticity and functional recovery in children with CP. PMID:25935686

  14. Special Reports.

    ERIC Educational Resources Information Center

    Wiant, Sarah K.; Lynch, Clifford; Nevins, Kate; Juergens, Bonnie

    1998-01-01

    Contains three special reports: developments in copyright law, 1997 (World Intellectual Property Organization (WIPO) legislation, Ashcroft Bill, No Electronic Theft Act, database protection, Conference on Fair Use (CONFU), judicial decisions, principles for licensing electronic resources, and Uniform Commercial Code Article 2B); Internet2 and the…

  15. Special Advocate.

    ERIC Educational Resources Information Center

    Vander Weele, Maribeth

    1992-01-01

    Thomas Hehir, special education chief of Chicago Public Schools, is evangelist of integrating children with disabilities into regular classrooms. By completely reorganizing department viewed as political patronage dumping ground, Hehir has made remarkable progress in handling large number of children awaiting evaluation and placement in special…

  16. Special Relativity

    NASA Astrophysics Data System (ADS)

    Sartori, L.; Murdin, P.

    2000-11-01

    The special theory of relativity (SR), developed by ALBERT EINSTEIN in 1905, represents a revolutionary change in the human conception of the nature of space and time. According to SR, space and time are not absolute but must be viewed as components of a single entity, SPACE-TIME. This idea has numerous important implications, both conceptual and practical....

  17. Specialized Mediation.

    ERIC Educational Resources Information Center

    Hammond, Carol; And Others

    1992-01-01

    Six articles discuss librarians as mediators in special circumstances. Highlights include the reference librarian and the information paraprofessional; effective reference mediation for nontraditional public library users, including mentally impaired patrons and illiterate adults; the academic librarian's role in the education process; and…

  18. Special Rules for Special Ed.

    ERIC Educational Resources Information Center

    Weatherly, Julie J.

    2000-01-01

    School districts are on safer legal ground if they recommend appropriate educational services for each special-needs child, convene parents and school personnel for Individual Education Plan meetings, make placement decisions based on individualized, thorough evaluations; document alternative options; develop behavior-management programs, and use…

  19. Special Relativity

    NASA Astrophysics Data System (ADS)

    Woodhouse, Nicholas M. J.

    This course on special relativity emphasizes the coordinate-free and tensorial approach to Einstein's theory. The author encourages the reader to look at problems from a four-dimensional point of view, so preparing them for further study in relativistic physics, gravitation and cosmology. The book will be especially appealing to students with a mathematical bent and those who like brevity and clarity of reasoning.

  20. Special technical assistance

    SciTech Connect

    Alexander, D.J.; Nanstad, R.K.; Sokolov, M.A.

    1995-10-01

    The purpose of this task is to perform various special analytical and experimental investigations to support the NRC in resolving regulatory research issues related to irradiation effects on materials. This task currently addresses two major areas: (1) providing technical expertise and assistance in the review of national codes and standards and (2) experimental evaluations of test specimens and practices and material properties.

  1. Special Milk Program

    ERIC Educational Resources Information Center

    US Department of Agriculture, 2009

    2009-01-01

    The Special Milk Program provides milk to children in schools, child care institutions and eligible camps that do not participate in other Federal child nutrition meal service programs. The program reimburses schools and institutions for the milk they serve. In 2008, 4,676 schools and residential child care institutions participated, along with…

  2. Special Operation. Module 20.

    ERIC Educational Resources Information Center

    South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

    This module on special operations, one in a series dealing with industrial sewing machines, their attachments, and operation, covers two topics: topstitching and mitering. For each topic these components are provided: an introduction, directions, an objective, learning activities, student information, a student self-check, and a check-out…

  3. Special Attachments. Module 19.

    ERIC Educational Resources Information Center

    South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

    This module on special attachments, one in a series dealing with industrial sewing machines, their attachments, and operation, covers four topics: gauges; cording attachment; zipper foot; and hemming, shirring, and binding. For each topic these components are provided: an introduction, directions, an objective, learning activities, student…

  4. Special Education: Procedural Guide.

    ERIC Educational Resources Information Center

    Dependents Schools (DOD), Washington, DC.

    The guide is intended to provide information to administrators and regional and local case study committees on special education procedures within Department of Defense Dependents Schools (DoDDS). The manual addresses a step-by step approach from referral to the implementation of individualized education programs (IEP). The following topics are…

  5. The Children's Home: Providing Services with Options

    ERIC Educational Resources Information Center

    Weaver, Robin

    2007-01-01

    This article describes how The Children's Home of Pittsburgh provides unique, specialized services for infants, children, and their families and seeks to improve not only the range of services available to these special patients, but also the way in which those services are provided. Their innovative healthcare programs have been developed in…

  6. 21. Providence & Worchester RR: Freight house. Providence, Providence Co., ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. Providence & Worchester RR: Freight house. Providence, Providence Co., RI. Sec. 4119, mp 185.66 (See HAER no. RI-3 for further documentation on this site.) - Northeast Railroad Corridor, Amtrak route between CT & MA state lines, Providence, Providence County, RI

  7. Specialized Summer Camps: Provide Benefits for Children and Families Alike

    ERIC Educational Resources Information Center

    Neff, John M.

    2009-01-01

    The arrival of summer signals a season of endless days of swimming, fishing, summer camps, and other outdoor activities. For children with chronic or terminal illnesses, it can be difficult to participate in many of these activities as well as challenging for parents to find summer camps that not only engage their children, but also offer the…

  8. Does the Health Maintenance Facility Provide Speciality Capabilities?

    NASA Technical Reports Server (NTRS)

    Boyce, Joey; Wurgler, James; Broadwell, Kim; Martin, William; Stiernberg, Charles M.; Bove, Alfred; Fromm, Rob; O'Neill, Daniel

    1991-01-01

    The Health Maintenance Facility (HMF) is capable of handling all minor illnesses, most moderate illnesses, and some major illnesses on board a space station. Its primary purpose should be to treat problems that are mission threatening, not life threatening. The HMF will have greater medical capabilities than those currently on Navy submarines. Much of the discussion in this document focuses on the possibilities of treating specific medical conditions on board a space station. The HMF will be limited to caring for critically ill patients for a few days, so a crew return vehicle will be important.

  9. Special Issue: "Functional Dendrimers".

    PubMed

    Tomalia, Donald A

    2016-01-01

    This special issue entitled "Functional Dendrimers" focuses on the manipulation of at least six "critical nanoscale design parameters" (CNDPs) of dendrimers including: size, shape, surface chemistry, flexibility/rigidity, architecture and elemental composition. These CNDPs collectively define properties of all "functional dendrimers". This special issue contains many interesting examples describing the manipulation of certain dendrimer CNDPs to create new emerging properties and, in some cases, predictive nanoperiodic property patterns (i.e., dendritic effects). The systematic engineering of CNDPs provides a valuable strategy for optimizing functional dendrimer properties for use in specific applications. PMID:27517890

  10. Web Resources for Special Education

    ERIC Educational Resources Information Center

    Singh, Delar K.

    2010-01-01

    The purpose of this paper is to provide brief descriptions and links to a number of reputed websites on various topics and issues of special education. The web sites are organized in the following categories: (1) Teaching in Inclusive Classroom, (2) Policies, Procedures, & Process of Special education, (3) Students with High Incidence…

  11. The "special K" in kaizen.

    PubMed

    McAtee, L F

    1999-05-01

    Do you want a strategy that guarantees the success of kaizen in your organization? This article will provide insights as to why one organization may succeed and another fails. Learn why the "Special K" is the difference. Idea will be presented on how to develop the "Special K" in others and ourselves. You will be challenged to become a "kaizener". PMID:10387784

  12. Special Programming for Displaced Homemakers.

    ERIC Educational Resources Information Center

    Swift, John S.; And Others

    1986-01-01

    Displaced homemakers returning to college need special services. These programs were developed by one university's center for women: Project Succeed, Back to School Workshops, and Special Programs to Build Self-Confidence. These programs were developed to provide on-the-job training while in college, help adults returning to college earn a degree,…

  13. Coaches' Training the Special Olympics Way.

    ERIC Educational Resources Information Center

    Roswal, Glenn M.

    1988-01-01

    The article describes the training provided prospective coaches of mentally retarded participants in Special Olympics at Special Olympics International Training Schools. Presentations on Special Olympics, mental retardation, athletic injury prevention, coaching techniques, and specific sports skills instruction are provided as well as direct…

  14. SPECIAL ENGLISH.

    ERIC Educational Resources Information Center

    English Language Services, Inc., Washington, DC.

    THIS 14-VOLUME SERIES OF TECHNICAL ENGLISH TEXTS IS DESIGNED TO PROVIDE PRACTICE IN TECHNICAL TERMINOLOGY FOR NON-NATIVE SPEAKERS OF ENGLISH. LANGUAGE FLUENCY LEVEL IS UPPER-INTERMEDIATE/ADVANCED. THE VARIOUS FIELDS OF INDUSTRY WHICH THE TEXTS DEAL WITH ARE AS FOLLOWS--(1) AGRICULTURE--BOOK 1, SOILS (2) AGRICULTURE--BOOK 2, FIELD CROPS (3)…

  15. Diversification, Evolution and Sub-Functionalization of 70kDa Heat-Shock Proteins in Two Sister Species of Antarctic Krill: Differences in Thermal Habitats, Responses and Implications under Climate Change

    PubMed Central

    Cascella, Kévin; Jollivet, Didier; Papot, Claire; Léger, Nelly; Corre, Erwan; Ravaux, Juliette; Clark, Melody S.; Toullec, Jean-Yves

    2015-01-01

    Background A comparative thermal tolerance study was undertaken on two sister species of Euphausiids (Antarctic krills) Euphausia superba and Euphausia crystallorophias. Both are essential components of the Southern Ocean ecosystem, but occupy distinct environmental geographical locations with slightly different temperature regimes. They therefore provide a useful model system for the investigation of adaptations to thermal tolerance. Methodology/Principal Finding Initial CTmax studies showed that E. superba was slightly more thermotolerant than E. crystallorophias. Five Hsp70 mRNAs were characterized from the RNAseq data of both species and subsequent expression kinetics studies revealed notable differences in induction of each of the 5 orthologues between the two species, with E. crystallorophias reacting more rapidly than E. superba. Furthermore, analyses conducted to estimate the evolutionary rates and selection strengths acting on each gene tended to support the hypothesis that diversifying selection has contributed to the diversification of this gene family, and led to the selective relaxation on the inducible C form with its possible loss of function in the two krill species. Conclusions The sensitivity of the epipelagic species E. crystallorophias to temperature variations and/or its adaptation to cold is enhanced when compared with its sister species, E. superba. These results indicate that ice krill could be the first of the two species to be impacted by the warming of coastal waters of the Austral ocean in the coming years due to climate change. PMID:25835552

  16. Concrete "Waffle" Provides Laser Beam Accuracy

    ERIC Educational Resources Information Center

    Building Design and Construction, 1978

    1978-01-01

    A massive concrete "waffle," riding on a bed of specially treated gravel and sand inside another building, provides the structural rigidity needed by the University of Rochester's Laboratory for Laser Energetics. (Author)

  17. Very special relativity.

    PubMed

    Cohen, Andrew G; Glashow, Sheldon L

    2006-07-14

    By very special relativity (VSR) we mean descriptions of nature whose space-time symmetries are certain proper subgroups of the Poincaré group. These subgroups contain space-time translations together with at least a two-parameter subgroup of the Lorentz group isomorphic to that generated by K(x) + J(y) and K(y)- J(x). We find that VSR implies special relativity (SR) in the context of local quantum field theory or of conservation. Absent both of these added hypotheses, VSR provides a simulacrum of SR for which most of the consequences of Lorentz invariance remain wholly or essentially intact, and for which many sensitive searches for departures from Lorentz invariance must fail. Several feasible experiments are discussed for which Lorentz-violating effects in VSR may be detectable. PMID:16907430

  18. Special Education in Mexico: One Community's Response.

    ERIC Educational Resources Information Center

    Shepherd, Terry L.; Contreras, Diana; Brown, Randel

    2002-01-01

    This article looks at the history of special education in Mexico, discusses the emergence of special education programs, and examines a school for special education in Nuevo Laredo, Tamaulipas. The school provides vocational training for students with a variety of disabilities and has a partnership with the local maquiladora industry. (Contains 5…

  19. Bridging Transition for Beginning Special Educators

    ERIC Educational Resources Information Center

    Wall-Marencik, Wendy

    2012-01-01

    This mixed-method study provides an analysis of student teachers' transition from a dual licensed special and general education program into beginning special education teaching. This two-wave investigation highlights developmental stages during student teaching, differences in experiences between special and general education student teaching…

  20. Special and Compensatory Programs: The Administrator's Role.

    ERIC Educational Resources Information Center

    Boschee, Floyd; Beyer, Bonnie M.; Engelking, Jeri L.; Boschee, Marlys Ann

    This textbook provides a comprehensive look at the vast knowledge base supporting special and compensatory education. Each chapter begins with a context and concludes with a section on the school administrator's role in promoting and leading others in each of the special and compensatory programs. Chapters include: (1) "Special Education," which…

  1. Maintenance and Loss of Duplicated Genes by Dosage Subfunctionalization.

    PubMed

    Gout, Jean-Francois; Lynch, Michael

    2015-08-01

    Whole-genome duplications (WGDs) have contributed to gene-repertoire enrichment in many eukaryotic lineages. However, most duplicated genes are eventually lost and it is still unclear why some duplicated genes are evolutionary successful whereas others quickly turn to pseudogenes. Here, we show that dosage constraints are major factors opposing post-WGD gene loss in several Paramecium species that share a common ancestral WGD. We propose a model where a majority of WGD-derived duplicates preserve their ancestral function and are retained to produce enough of the proteins performing this same ancestral function. Under this model, the expression level of individual duplicated genes can evolve neutrally as long as they maintain a roughly constant summed expression, and this allows random genetic drift toward uneven contributions of the two copies to total expression. Our analysis suggests that once a high level of imbalance is reached, which can require substantial lengths of time, the copy with the lowest expression level contributes a small enough fraction of the total expression that selection no longer opposes its loss. Extension of our analysis to yeast species sharing a common ancestral WGD yields similar results, suggesting that duplicated-gene retention for dosage constraints followed by divergence in expression level and eventual deterministic gene loss might be a universal feature of post-WGD evolution. PMID:25908670

  2. Project SCS (Special Communication Services).

    ERIC Educational Resources Information Center

    Curtis, John A.

    This extensive report describes and provides documentation on Special Communications Services for the Sensory Impaired (SCS), a Virginia-based telecommunications delivery system developed by the Center for Excellence, Inc. (CenTex), to provide information and entertainment broadcasting services to the visually handicapped, the hearing impaired,…

  3. NATIONAL HEALTH PROVIDER INVENTORY

    EPA Science Inventory

    The National Health Provider Inventory provides data on services, location, staff, capacity, and other characteristics of selected health care providers in the United States. Information is collected via mail questionnaire with telephone follow up to all providers (100% census) o...

  4. 38 CFR 61.40 - Special need grants-general.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Special need grants... (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM Special Need Grants § 61.40 Special need grants—general. (a) VA provides special need grants to public or nonprofit private entities that will create...

  5. 38 CFR 61.40 - Special need grants-general.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Special need grants... (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM Special Need Grants § 61.40 Special need grants—general. (a) VA provides special need grants to public or nonprofit private entities that will create...

  6. Ethics and Special Education.

    ERIC Educational Resources Information Center

    Paul, James; French, Peter; Cranston-Gingras, Ann

    2001-01-01

    Discussion of ethics in special education focuses on four challenges: (1) examination of special education's history within an ethical framework; (2) articulation of character morality as well as choice morality in special education ethical dilemmas; (3) examination of special education in a liberal democracy; and (4) development of an ethical…

  7. Special Education in Korea.

    ERIC Educational Resources Information Center

    Kim, Byung Ha, Ed.; Yeo, Kwang Eung

    The text on special education in Korea is divided into four major sections--a brief history of special education in Korea, the present status of special education in Korea, the special education plan of the Young Kwang Educational Foundation, and directory of schools and classes for the exceptional in Korea. Topics covered include the following:…

  8. Health Care Provider Initiative Strategic Plan

    ERIC Educational Resources Information Center

    National Environmental Education & Training Foundation, 2012

    2012-01-01

    This document lays out the strategy for achieving the goals and objectives of NEETF's "Health Care Provider Initiative." The goal of NEETF's "Health Care Provider Initiative" is to incorporate environmental health into health professionals' education and practice in order to improve health care and public health, with a special emphasis on…

  9. Provide, provide: the economics of aging.

    PubMed

    1998-06-26

    Most older persons face two potentially serious economic problems: (a) declining earning power and (b) declining health that can be partly offset by increased utilization of health care. The decline in earning power is largely attributable to physiological changes and to obsolescence of skills and knowledge. These adverse effects are exacerbated by public and private policies that reduce the incentives of older persons to continue work and increase the cost to employers of employing older workers. The problems of earnings replacement and health care payment are usually discussed separately, but there are several reasons why they should be considered together. First, there are often tradeoffs between the two. Money is money, and for most people there is never enough to go around. This is self-evident where private funds are concerned. Low-income elderly, for instance, frequently must choose between expensive prescription drugs and an adequate diet. For middle-income elderly, the choice may be between saving on medigap insurance or forgoing an airplane trip to a grandchild's graduation. Difficult choices are also inherent in the allocation of public funds. The same tax receipts that could be used to maintain or increase retirement benefits could be used to fund additional care, and vice versa. In discussing these tradeoffs, some analysts assert that people will gladly give up other goods and services for medical care that cures illness, relieves pain, or restores function. Others believe that some people would forgo some health insurance in order to maintain access to other goods and services. A second reason for looking at the two problems together is that they pose similar questions for public policy. How much should each generation provide for its own needs in old age, and how much should be provided by the generations that follow? How much provision should be voluntary, how much compulsory? How much intra-generational redistribution is appropriate after age 65

  10. Social Security's special minimum benefit.

    PubMed

    Olsen, K A; Hoffmeyer, D

    Social Security's special minimum primary insurance amount (PIA) provision was enacted in 1972 to increase the adequacy of benefits for regular long-term, low-earning covered workers and their dependents or survivors. At the time, Social Security also had a regular minimum benefit provision for persons with low lifetime average earnings and their families. Concerns were rising that the low lifetime average earnings of many regular minimum beneficiaries resulted from sporadic attachment to the covered workforce rather than from low wages. The special minimum benefit was seen as a way to reward regular, low-earning workers without providing the windfalls that would have resulted from raising the regular minimum benefit to a much higher level. The regular minimum benefit was subsequently eliminated for workers reaching age 62, becoming disabled, or dying after 1981. Under current law, the special minimum benefit will phase out over time, although it is not clear from the legislative history that this was Congress's explicit intent. The phaseout results from two factors: (1) special minimum benefits are paid only if they are higher than benefits payable under the regular PIA formula, and (2) the value of the regular PIA formula, which is indexed to wages before benefit eligibility, has increased faster than that of the special minimum PIA, which is indexed to inflation. Under the Social Security Trustees' 2000 intermediate assumptions, the special minimum benefit will cease to be payable to retired workers attaining eligibility in 2013 and later. Their benefits will always be larger under the regular benefit formula. As policymakers consider Social Security solvency initiatives--particularly proposals that would reduce benefits or introduce investment risk--interest may increase in restoring some type of special minimum benefit as a targeted protection for long-term low earners. Two of the three reform proposals offered by the President's Commission to Strengthen

  11. Special Education in Nigeria.

    ERIC Educational Resources Information Center

    Abang, Theresa B.

    1992-01-01

    This article discusses the special education system in Nigeria, focusing on integration; training of special educators; medical, health, and welfare services for children with disabilities; recreational facilities; employment opportunities; national planning; and problems and successes. (JDD)

  12. Algorithmically specialized parallel computers

    SciTech Connect

    Snyder, L.; Jamieson, L.H.; Gannon, D.B.; Siegel, H.J.

    1985-01-01

    This book is based on a workshop which dealt with array processors. Topics considered include algorithmic specialization using VLSI, innovative architectures, signal processing, speech recognition, image processing, specialized architectures for numerical computations, and general-purpose computers.

  13. Codes with special correlation.

    NASA Technical Reports Server (NTRS)

    Baumert, L. D.

    1964-01-01

    Uniform binary codes with special correlation including transorthogonality and simplex code, Hadamard matrices and difference sets uniform binary codes with special correlation including transorthogonality and simplex code, Hadamard matrices and difference sets

  14. Managing Special and Inclusive Education

    ERIC Educational Resources Information Center

    Rayner, Steve G.

    2007-01-01

    This book is a guide to special and inclusive education and provides a comprehensive overview of this complex field. Author Stephen Rayner examines context, policy, and practice, and shows how to successfully navigate the managerial challenges involved, while contributing to the way forward through leadership in a diverse field. The author…

  15. Early Childhood Special Music Education

    ERIC Educational Resources Information Center

    Darrow, Alice-Ann

    2011-01-01

    The process of early intervention is a critical component of Early Childhood Special Music Education. Early intervention is the process of providing services, education, and support to young children who have disabilities or to children who are at-risk of developing needs that may affect their physical, cognitive, or emotional development. The…

  16. A Specialization for Speech Perception.

    ERIC Educational Resources Information Center

    Liberman, Alvin M.; Mattingly, Ignatius G.

    1989-01-01

    Discusses the phonetic module that increases the rate of information flow, establishes the parity between sender and receiver, and provides for the natural development of phonetic structures in the individual. Cites evidence and function of this specialization and architectural relations between the two classes of modules. (Author/RT)

  17. MCPS Special Education at a Glance 2007-2008

    ERIC Educational Resources Information Center

    Montgomery County Public Schools, 2008

    2008-01-01

    Montgomery County Public Schools (MCPS) "Special Education at a Glance," which includes a copy of the "Guide to Planning and Assessing School-Based Special Education Programs," provides in a single document, information about the special education population at each MCPS school, including enrollment, staffing, special education…

  18. Mentorship of Special Educators

    ERIC Educational Resources Information Center

    Madigan, Jennifer Booker; Schroth-Cavataio, Georganne

    2012-01-01

    The national shortage and exceptionally high attrition rate of special education teachers are impediments to serving students with special needs. Given that only 64 percent of special education teachers have access to a mentor compared with 86 percent of general education teachers, this book meets an essential need for attracting, retaining, and…

  19. Special Effects Activity Guide.

    ERIC Educational Resources Information Center

    Boxer, Jennifer; Valenta, Carol

    This guide accompanies "Special Effects," a 40-minute IMAX film and "Special Effects II", a multimedia, interactive traveling exhibit designed by the California Museum of Science and Industry. The exhibit focuses on the underlying scientific and technical processes of special effects from the earliest motion picture to state-of-the-art digital…

  20. Mentoring Special Populations

    ERIC Educational Resources Information Center

    Whitfield, Keith E.; Edwards, Christopher L.

    2011-01-01

    Mentorship is critical for career development. Members of special populations are at increased risk of information shortfalls and advice that is not framed with cultural sensitivity. Special knowledge and skills are needed to successfully mentor members of ethnic minority and other special populations. Midlevel and senior scientists need…

  1. Assessing Special Educational Needs.

    ERIC Educational Resources Information Center

    Wolfendale, Sheila, Ed.

    This essays in this book contain valuable and up-to-date information about current issues and developments in assessing special educational needs. The context of the book is the mainstream setting in the United Kingdom. The aim of these chapters is to consider special needs in inclusive education, consistent with British special needs legislation.…

  2. Chemistry and Special Education

    NASA Astrophysics Data System (ADS)

    Riendl, Pamela A.; Haworth, Daniel T.

    1995-11-01

    Secondary and post-secondary science teachers are beginning to see increasing numbers of students with mild disabilities enrolled in their classes. These students can be classified as having one of a variety of mild disabilities that might impact the way they receive and process educational information. As a result of the passage in 1975 of PL 94-142, the Individuals with Disabilities Act (IDEA), disabled students now have the opportunity to receive special education in the public schools and to be placed in regular classrooms whenever possible. Very little information for science teachers is provided in teacher preparation courses or is available in the literature to offer concrete suggestions for teaching science to these students. This paper describes the political gains made in education for the disabled, identifies various types of mild disabilities, and suggests possible teaching interventions for the chemistry teacher who has a student with a mild disability.

  3. Special nuclear material simulation device

    SciTech Connect

    Leckey, John H.; DeMint, Amy; Gooch, Jack; Hawk, Todd; Pickett, Chris A.; Blessinger, Chris; York, Robbie L.

    2014-08-12

    An apparatus for simulating special nuclear material is provided. The apparatus typically contains a small quantity of special nuclear material (SNM) in a configuration that simulates a much larger quantity of SNM. Generally the apparatus includes a spherical shell that is formed from an alloy containing a small quantity of highly enriched uranium. Also typically provided is a core of depleted uranium. A spacer, typically aluminum, may be used to separate the depleted uranium from the shell of uranium alloy. A cladding, typically made of titanium, is provided to seal the source. Methods are provided to simulate SNM for testing radiation monitoring portals. Typically the methods use at least one primary SNM spectral line and exclude at least one secondary SNM spectral line.

  4. Specialization and competition in healthcare delivery networks.

    PubMed

    Tiwari, Vikram; Heese, H Sebastian

    2009-09-01

    Hospital networks, which offer multiple services at multiple locations, are investigating strategies to fight the growing competition from specialty hospitals. Specialty hospitals focus on a selective range of profitable services, have better control over costs, and deliver higher (perceived) quality. A hospital network too can create specialized facilities; however, this may lead to the loss of sales from services that it no longer offers. Using a spatial model, we study when it is profitable for the network to specialize, and how to determine which facilities provide the greatest value through specialization. We find that a hospital network, when facing specialized competitors, can often improve its overall profitability by specializing some of its facilities; and that among its different facilities, the network's best choice for specialization is the facility that is closest to the competitor, and thus most directly affected. Interestingly, we find that the value of specialization is contingent upon the competitive pressure that the specialized competitor exerts on the network. Specializing one facility yields the greatest benefits for the network when the competitor is located at the fringe of the market, thus presenting a reduced threat to the hospital network. On the other hand, if the specialized competitor is located at the core of the network's customer base, we find that the attractiveness of specializing one facility is much smaller and that the hospital network might fare better with a strategy based on diversification, i.e., offering a full-menu of services at every facility. PMID:19739362

  5. Arizona's Application Service Provider.

    ERIC Educational Resources Information Center

    Jordan, Darla

    2002-01-01

    Describes the U.S.'s first statewide K-12 application service provider (ASP). The ASP, implemented by the Arizona School Facilities Board, provides access to productivity, communications, and education software programs from any Internet-enabled device, whether in the classroom or home. (EV)

  6. Provider 1997 corporate profiles.

    PubMed

    1997-05-01

    As the long term care industry seeks out new products, new solutions, and new ways of providing quality care, it is important for long term care providers to know more about the companies they do business with. The following corporate profiles showcase information about leading companies in the long term health care industry. Some of the areas highlighted include: mission of company, history, product lines, support services. We hope you will find this information useful when making purchasing decisions, and we're confident you'll keep this issue of Provider as a handy reference guide. The information in the following corporate profiles was supplied by the companies. Neither Provider magazine nor the American Health Care Association endorses the products and services listed in this section. Provider magazine and the American Health Care Association disclaim any and all liability related to or arising from the information contained in the profiles. PMID:10166888

  7. What's so special about cholesterol?

    PubMed

    Mouritsen, Ole G; Zuckermann, Martin J

    2004-11-01

    Cholesterol (or other higher sterols such as ergosterol and phytosterols) is universally present in large amounts (20-40 mol%) in eukaryotic plasma membranes, whereas it is universally absent in the membranes of prokaryotes. Cholesterol has a unique ability to increase lipid order in fluid membranes while maintaining fluidity and diffusion rates. Cholesterol imparts low permeability barriers to lipid membranes and provides for large mechanical coherence. A short topical review is given of these special properties of cholesterol in relation to the structure of membranes, with results drawn from a variety of theoretical and experimental studies. Particular focus is put on cholesterol's ability to promote a special membrane phase, the liquid-ordered phase, which is unique for cholesterol (and other higher sterols like ergosterol) and absent in membranes containing the cholesterol precursor lanosterol. Cholesterol's role in the formation of special membrane domains and so-called rafts is discussed. PMID:15726825

  8. Tupaia small RNAs provide insights into function and evolution of RNAi-based transposon defense in mammals

    PubMed Central

    Rosenkranz, David; Rudloff, Stefanie; Bastuck, Katharina; Ketting, René F.; Zischler, Hans

    2015-01-01

    Argonaute proteins comprising Piwi-like and Argonaute-like proteins and their guiding small RNAs combat mobile DNA on the transcriptional and post-transcriptional level. While Piwi-like proteins and associated piRNAs are generally restricted to the germline, Argonaute-like proteins and siRNAs have been linked with transposon control in the germline as well as in the soma. Intriguingly, evolution has realized distinct Argonaute subfunctionalization patterns in different species but our knowledge about mammalian RNA interference pathways relies mainly on findings from the mouse model. However, mice differ from other mammals by absence of functional Piwil3 and expression of an oocyte-specific Dicer isoform. Thus, studies beyond the mouse model are required for a thorough understanding of function and evolution of mammalian RNA interference pathways. We high-throughput sequenced small RNAs from the male Tupaia belangeri germline, which represents a close outgroup to primates, hence phylogenetically links mice with humans. We identified transposon-derived piRNAs as well as siRNAs clearly contrasting the separation of piRNA- and siRNA-pathways into male and female germline as seen in mice. Genome-wide analysis of tree shrew transposons reveal that putative siRNAs map to transposon sites that form foldback secondary structures thus representing suitable Dicer substrates. In contrast piRNAs target transposon sites that remain accessible. With this we provide a basic mechanistic explanation how secondary structure of transposon transcripts influences piRNA- and siRNA-pathway utilization. Finally, our analyses of tree shrew piRNA clusters indicate A-Myb and the testis-expressed transcription factor RFX4 to be involved in the transcriptional regulation of mammalian piRNA clusters. PMID:25802409

  9. Tupaia small RNAs provide insights into function and evolution of RNAi-based transposon defense in mammals.

    PubMed

    Rosenkranz, David; Rudloff, Stefanie; Bastuck, Katharina; Ketting, René F; Zischler, Hans

    2015-05-01

    Argonaute proteins comprising Piwi-like and Argonaute-like proteins and their guiding small RNAs combat mobile DNA on the transcriptional and post-transcriptional level. While Piwi-like proteins and associated piRNAs are generally restricted to the germline, Argonaute-like proteins and siRNAs have been linked with transposon control in the germline as well as in the soma. Intriguingly, evolution has realized distinct Argonaute subfunctionalization patterns in different species but our knowledge about mammalian RNA interference pathways relies mainly on findings from the mouse model. However, mice differ from other mammals by absence of functional Piwil3 and expression of an oocyte-specific Dicer isoform. Thus, studies beyond the mouse model are required for a thorough understanding of function and evolution of mammalian RNA interference pathways. We high-throughput sequenced small RNAs from the male Tupaia belangeri germline, which represents a close outgroup to primates, hence phylogenetically links mice with humans. We identified transposon-derived piRNAs as well as siRNAs clearly contrasting the separation of piRNA- and siRNA-pathways into male and female germline as seen in mice. Genome-wide analysis of tree shrew transposons reveal that putative siRNAs map to transposon sites that form foldback secondary structures thus representing suitable Dicer substrates. In contrast piRNAs target transposon sites that remain accessible. With this we provide a basic mechanistic explanation how secondary structure of transposon transcripts influences piRNA- and siRNA-pathway utilization. Finally, our analyses of tree shrew piRNA clusters indicate A-Myb and the testis-expressed transcription factor RFX4 to be involved in the transcriptional regulation of mammalian piRNA clusters. PMID:25802409

  10. Providing for Different Rates of Music Learning.

    ERIC Educational Resources Information Center

    Beer, Alice S.; And Others

    1982-01-01

    Discusses ways that elementary music teachers can design class activities which will meet individual needs of mainstreamed special students. Activities described encompass a wide range of difficulty and provide opportunities for individualized, small-group or out-of-class instruction and for creative response. (AM)

  11. 36 CFR 1002.50 - Special events.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false Special events. 1002.50... RECREATION § 1002.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however, There is a meaningful...

  12. 36 CFR 2.50 - Special events.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Special events. 2.50 Section... PROTECTION, PUBLIC USE AND RECREATION § 2.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however,...

  13. 36 CFR 2.50 - Special events.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Special events. 2.50 Section... PROTECTION, PUBLIC USE AND RECREATION § 2.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however,...

  14. 36 CFR 2.50 - Special events.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Special events. 2.50 Section... PROTECTION, PUBLIC USE AND RECREATION § 2.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however,...

  15. 36 CFR 2.50 - Special events.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Special events. 2.50 Section... PROTECTION, PUBLIC USE AND RECREATION § 2.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however,...

  16. 36 CFR 1002.50 - Special events.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false Special events. 1002.50... RECREATION § 1002.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however, There is a meaningful...

  17. 36 CFR 1002.50 - Special events.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Special events. 1002.50... RECREATION § 1002.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however, There is a meaningful...

  18. 36 CFR 1002.50 - Special events.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Special events. 1002.50... RECREATION § 1002.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however, There is a meaningful...

  19. 36 CFR 2.50 - Special events.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Special events. 2.50 Section... PROTECTION, PUBLIC USE AND RECREATION § 2.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however,...

  20. 36 CFR 1002.50 - Special events.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true Special events. 1002.50... RECREATION § 1002.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however, There is a meaningful...

  1. Special Education Research Advances Knowledge in Education

    ERIC Educational Resources Information Center

    Vaughn, Sharon; Swanson, Elizabeth A.

    2015-01-01

    Research in special education has yielded beneficial outcomes for students with disabilities as well as typical achieving students. The authors provide examples of the valuable knowledge special education research has generated, including the elements of response to intervention (e.g., screening and progress monitoring), instructional practices…

  2. Preparing Urban Special Education Leaders: What Works

    ERIC Educational Resources Information Center

    Martin, Suzanne M.; Little, Joyce; Miller, Katie; Gourwitz, Jillian

    2014-01-01

    Special education administrators play a critical role in the implementation of successful inclusion in diverse, standards-based environments. They provide the vision and leadership necessary to guide educators in both general and special education as they deliver instructional programs to meet the needs of diverse students with disabilities.…

  3. Distinguishing Disability: Parents, Privilege, and Special Education

    ERIC Educational Resources Information Center

    Ong-Dean, Colin

    2009-01-01

    Students in special education programs can have widely divergent experiences. For some, special education amounts to a dumping ground where schools unload their problem students, while for others, it provides access to services and accommodations that drastically improve chances of succeeding in school and beyond. "Distinguishing Disability"…

  4. Hiring an Effective Special Education Teacher

    ERIC Educational Resources Information Center

    Fenlon, Amanda

    2008-01-01

    The task of hiring special education teachers may seem daunting because they serve in what is undeniably the most complex of teaching roles. This article provides guidance and suggestions for identifying key competencies that a viable special education teacher candidate should possess. Although many building leaders may still subscribe to gut…

  5. 40 CFR 435.51 - Specialized definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Subcategory § 435.51 Specialized definitions. For the purpose of this subpart: (a) Except as provided below... 40 Protection of Environment 30 2011-07-01 2011-07-01 false Specialized definitions. 435.51 Section 435.51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT...

  6. 36 CFR 261.53 - Special closures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Special closures. 261.53 Section 261.53 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PROHIBITIONS Prohibitions in Areas Designated by Order § 261.53 Special closures. When provided in an order, it is prohibited to go into or be upon any...

  7. 36 CFR 261.53 - Special closures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Special closures. 261.53 Section 261.53 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PROHIBITIONS Prohibitions in Areas Designated by Order § 261.53 Special closures. When provided in an order, it is prohibited to go into or be upon any...

  8. 36 CFR 261.53 - Special closures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Special closures. 261.53 Section 261.53 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PROHIBITIONS Prohibitions in Areas Designated by Order § 261.53 Special closures. When provided in an order, it is prohibited to go into or be upon any...

  9. 36 CFR 261.53 - Special closures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false Special closures. 261.53 Section 261.53 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PROHIBITIONS Prohibitions in Areas Designated by Order § 261.53 Special closures. When provided in an order, it is prohibited to go into or be upon any...

  10. 36 CFR 261.53 - Special closures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Special closures. 261.53 Section 261.53 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PROHIBITIONS Prohibitions in Areas Designated by Order § 261.53 Special closures. When provided in an order, it is prohibited to go into or be upon any...

  11. Auditory Learning Materials for Special Education: Catalog.

    ERIC Educational Resources Information Center

    Smith, Marsha C.; O'Connor, Phyllis

    The catalog (developed by the Great Lakes Region Special Education Instructional Materials Center) provides information on more than 100 auditory learning materials for use in special education. Described in the first section of the catalog are procedures used to evaluate and classify auditory instructional materials, including a list of…

  12. Special Olympics: The Rest of the Storey

    ERIC Educational Resources Information Center

    MacLean, William E., Jr.

    2008-01-01

    In this article, Keith Storey provides a modest update to his earlier case against the Special Olympics. Several sections have been updated, with some additional consideration of issues related to severe disabilities. The article now includes sections on choice and self-determination and use of taxpayer dollars to fund Special Olympics programs.…

  13. Reaching Out for Special-Needs Support

    ERIC Educational Resources Information Center

    Castro, Christy; Duvall, Steven; Wheeler, Ann

    2010-01-01

    Providing services for students with disabilities can be costly for school districts. Districts are required by law to fund the primary expenses of a special-education program; however, most spend far more than is legally mandatory. This situation puts those districts without sufficient resources to meet their obligations to educate special-needs…

  14. Disproportionality in Special Needs Education in England

    ERIC Educational Resources Information Center

    Dyson, Alan; Gallannaugh, Frances

    2008-01-01

    Unlike the United States, England does not have a special education system based on the identification of students as having disabilities of one or another type. Instead, the English system enables help to be provided to students on the basis of assessments of their individual "special educational needs." The authors consider the implications of…

  15. Special Education in Arab Countries: Current Challenges

    ERIC Educational Resources Information Center

    Hadidi, Muna S.; Al Khateeb, Jamal M.

    2015-01-01

    Arab countries have undertaken various measures to develop special education programmes and services over the last three decades; nevertheless, major challenges remain regarding the expansion of these programmes and services and improving their quality. "This article provides an update on disability and special education in Arab…

  16. 28 CFR 42.714 - Special benefits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Special benefits. 42.714 Section 42.714 Judicial Administration DEPARTMENT OF JUSTICE NONDISCRIMINATION; EQUAL EMPLOYMENT OPPORTUNITY; POLICIES AND... benefits. If a recipient operating a program or activity provides special benefits to the elderly or...

  17. 28 CFR 42.714 - Special benefits.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Special benefits. 42.714 Section 42.714 Judicial Administration DEPARTMENT OF JUSTICE NONDISCRIMINATION; EQUAL EMPLOYMENT OPPORTUNITY; POLICIES AND... benefits. If a recipient operating a program or activity provides special benefits to the elderly or...

  18. 28 CFR 42.714 - Special benefits.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Special benefits. 42.714 Section 42.714 Judicial Administration DEPARTMENT OF JUSTICE NONDISCRIMINATION; EQUAL EMPLOYMENT OPPORTUNITY; POLICIES AND... benefits. If a recipient operating a program or activity provides special benefits to the elderly or...

  19. 28 CFR 42.714 - Special benefits.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Special benefits. 42.714 Section 42.714 Judicial Administration DEPARTMENT OF JUSTICE NONDISCRIMINATION; EQUAL EMPLOYMENT OPPORTUNITY; POLICIES AND... benefits. If a recipient operating a program or activity provides special benefits to the elderly or...

  20. 28 CFR 42.714 - Special benefits.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Special benefits. 42.714 Section 42.714 Judicial Administration DEPARTMENT OF JUSTICE NONDISCRIMINATION; EQUAL EMPLOYMENT OPPORTUNITY; POLICIES AND... benefits. If a recipient operating a program or activity provides special benefits to the elderly or...

  1. West Asian Special Libraries and Information Centers.

    ERIC Educational Resources Information Center

    Harvey, John F.

    Special libraries are defined in this paper as those libraries serving such institutions as government offices, private corporations, associations, and university departments. Information centers are similar to special libraries but provide personalized, high quality reference service, usually in science and technology, and often using mechanical…

  2. Selected Topics in International Special Education.

    ERIC Educational Resources Information Center

    Kelly, Nancy

    2002-01-01

    This article provides information on special education topics on the international front. Information is presented on projects that evaluated early intervention programs, a life-centered career education program in the Philippines, a Peruvian vocational program for individuals with severe disabilities, and special classes for children with…

  3. California Master Plan for Special Education.

    ERIC Educational Resources Information Center

    California State Dept. of Education, Sacramento.

    Reported is California's master plan for providing a quality educational program to all of the state's handicapped children. Topics covered include a definition of special education, interaction between special education and general education, and a look at California's programs including new directions and current weaknesses. Presented are a…

  4. Testing Provides Crucial Information

    ERIC Educational Resources Information Center

    Morial, Marc H.

    2015-01-01

    The National Urban League president and CEO Marc H. Morial weighs in on what he sees as the need for continued annual assessments of students, rejecting the course of opting out that has taken hold in some places across America. Assessment data provides students with the opportunity to receive personalized supports and necessary interventions to…

  5. Providers get their due.

    PubMed

    Morrissey, J

    1994-11-01

    Providers are getting their due, but only after employing computer software programs to help sort through the complex managed-care contracts they've negotiated. More and more accounting departments are relying on contract management systems to ensure accurate billing. PMID:10138187

  6. The Provident Principal.

    ERIC Educational Resources Information Center

    McCall, John R.

    This monograph offers leadership approaches for school principals. Discussion applies the business leadership theory of Warren Bennis and Burt Nanus to the role of the principal. Each of the booklet's three parts concludes with discussion questions. Part 1, "Visions and Values for the Provident Principal," demonstrates the importance of…

  7. Achieving Provider Engagement

    PubMed Central

    Greenfield, Geva; Pappas, Yannis; Car, Josip; Majeed, Azeem; Harris, Matthew

    2014-01-01

    The literature on integrated care is limited with respect to practical learning and experience. Although some attention has been paid to organizational processes and structures, not enough is paid to people, relationships, and the importance of these in bringing about integration. Little is known, for example, about provider engagement in the organizational change process, how to obtain and maintain it, and how it is demonstrated in the delivery of integrated care. Based on qualitative data from the evaluation of a large-scale integrated care initiative in London, United Kingdom, we explored the role of provider engagement in effective integration of services. Using thematic analysis, we identified an evolving engagement narrative with three distinct phases: enthusiasm, antipathy, and ambivalence, and argue that health care managers need to be aware of the impact of professional engagement to succeed in advancing the integrated care agenda. PMID:25212855

  8. Why healthcare providers merge.

    PubMed

    Postma, Jeroen; Roos, Anne-Fleur

    2016-04-01

    In many OECD countries, healthcare sectors have become increasingly concentrated as a result of mergers. However, detailed empirical insight into why healthcare providers merge is lacking. Also, we know little about the influence of national healthcare policies on mergers. We fill this gap in the literature by conducting a survey study on mergers among 848 Dutch healthcare executives, of which 35% responded (resulting in a study sample of 239 executives). A total of 65% of the respondents was involved in at least one merger between 2005 and 2012. During this period, Dutch healthcare providers faced a number of policy changes, including increasing competition, more pressure from purchasers, growing financial risks, de-institutionalisation of long-term care and decentralisation of healthcare services to municipalities. Our empirical study shows that healthcare providers predominantly merge to improve the provision of healthcare services and to strengthen their market position. Also efficiency and financial reasons are important drivers of merger activity in healthcare. We find that motives for merger are related to changes in health policies, in particular to the increasing pressure from competitors, insurers and municipalities. PMID:26055501

  9. PROVIDING WOMEN, KEPT MEN

    PubMed Central

    Mojola, Sanyu A

    2014-01-01

    This paper draws on ethnographic and interview based fieldwork to explore accounts of intimate relationships between widowed women and poor young men that emerged in the wake of economic crisis and a devastating HIV epidemic among the Luo ethnic group in Western Kenya. I show how the cooptation of widow inheritance practices in the wake of an overwhelming number of widows as well as economic crisis resulted in widows becoming providing women and poor young men becoming kept men. I illustrate how widows in this setting, by performing a set of practices central to what it meant to be a man in this society – pursuing and providing for their partners - were effectively doing masculinity. I will also show how young men, rather than being feminized by being kept, deployed other sets of practices to prove their masculinity and live in a manner congruent with cultural ideals. I argue that ultimately, women’s practice of masculinity in large part seemed to serve patriarchal ends. It not only facilitated the fulfillment of patriarchal expectations of femininity – to being inherited – but also served, in the end, to provide a material base for young men’s deployment of legitimizing and culturally valued sets of masculine practice. PMID:25489121

  10. Provider panel presentations.

    PubMed

    Buckelew, Larry C; Harvey, Deborah; Mello, Joe

    2003-08-01

    To wrap up the three big items--attracting talent, the professional nurse role, and our structural disadvantages--I would offer the following take-away thoughts: We ought to do what we can to get our disproportionate share of RNs out of the health care system to work in dialysis. If we work together, we have a shot at making that happen. As an industry, we must exploit our strengths. We have to exploit the pride that comes in the services and the care that we provide. We need to create in a very visual way that difference for nurses who are considering which area of specialty to go into and where to create their careers. We, as providers, have a huge opportunity to create the right environment for our nurses. That's something we own. We have to fix it. We have to create a better place to work for nurses than any place else. We must create a more enriching place for nurses than anywhere else. That's up to us. I know a lot of us on the provider side are doing tons of things to make that happen and we need to keep driving that. We need a level playing field. We've proven the fact that we can deliver clinical outcomes with the best. Now we need help from our biggest customer to make sure we can compete for the resources that are necessary to sustain and improve those clinical outcomes on an ongoing basis. PMID:14533522

  11. 15 CFR 2301.5 - Special consideration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... natives; Asian or Pacific Islanders, Hispanics, and Blacks, not of Hispanic Origin. The special consideration element is provided as one of several evaluation criteria contained in the regulations at 15...

  12. 15 CFR 2301.5 - Special consideration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... natives; Asian or Pacific Islanders, Hispanics, and Blacks, not of Hispanic Origin. The special consideration element is provided as one of several evaluation criteria contained in the regulations at 15...

  13. 15 CFR 2301.5 - Special consideration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... natives; Asian or Pacific Islanders, Hispanics, and Blacks, not of Hispanic Origin. The special consideration element is provided as one of several evaluation criteria contained in the regulations at 15...

  14. 15 CFR 2301.5 - Special consideration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... natives; Asian or Pacific Islanders, Hispanics, and Blacks, not of Hispanic Origin. The special consideration element is provided as one of several evaluation criteria contained in the regulations at 15...

  15. 47 CFR 15.27 - Special accessories.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... manual is provided only in a form other than paper, such as on a computer disk or over the Internet, the... requiring special accessories is installed by or under the supervision of the party marketing the device,...

  16. 47 CFR 15.27 - Special accessories.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... manual is provided only in a form other than paper, such as on a computer disk or over the Internet, the... requiring special accessories is installed by or under the supervision of the party marketing the device,...

  17. 47 CFR 15.27 - Special accessories.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... manual is provided only in a form other than paper, such as on a computer disk or over the Internet, the... requiring special accessories is installed by or under the supervision of the party marketing the device,...

  18. 40 CFR 407.51 - Specialized definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Potato Products Subcategory § 407.51 Specialized definitions. For the purpose of this subpart: (a) Except as provided below, the general definitions, abbreviations and methods of analysis set forth in 40...

  19. 40 CFR 407.41 - Specialized definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Potato Products Subcategory § 407.41 Specialized definitions. For the purpose of this subpart: (a) Except as provided below, the general definitions, abbreviations and methods of analysis set forth in 40...

  20. The 1986 Get Away Special Experimenter's Symposium

    NASA Technical Reports Server (NTRS)

    Thomas, Lawrence R. (Editor); Mosier, Frances L. (Editor)

    1987-01-01

    The 1986 Get Away Special (GAS) Experimenter's Symposium will provide a formal opportunity for GAS Experimenter's to share the results of their projects. The focus of this symposium is on payloads that will be flown in the future.

  1. 40 CFR 417.31 - Specialized definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Neutralization Subcategory § 417.31 Specialized definitions. For the purpose of this subpart: (a) Except as provided below, the general definitions, abbreviations and methods of analysis set forth in 40 CFR part...

  2. 40 CFR 417.31 - Specialized definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Neutralization Subcategory § 417.31 Specialized definitions. For the purpose of this subpart: (a) Except as provided below, the general definitions, abbreviations and methods of analysis set forth in 40 CFR part...

  3. 40 CFR 417.31 - Specialized definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Neutralization Subcategory § 417.31 Specialized definitions. For the purpose of this subpart: (a) Except as provided below, the general definitions, abbreviations and methods of analysis set forth in 40 CFR part...

  4. 40 CFR 417.31 - Specialized definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Neutralization Subcategory § 417.31 Specialized definitions. For the purpose of this subpart: (a) Except as provided below, the general definitions, abbreviations and methods of analysis set forth in 40 CFR part...

  5. 40 CFR 417.31 - Specialized definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Neutralization Subcategory § 417.31 Specialized definitions. For the purpose of this subpart: (a) Except as provided below, the general definitions, abbreviations and methods of analysis set forth in 40 CFR part...

  6. Special Education in Bangladesh.

    ERIC Educational Resources Information Center

    Zaman, Sultana S.; Munir, Shirin Z.

    1992-01-01

    This review of special education in Bangladesh describes the prevalence of major disabilities and government and nongovernment programs for children with various types of disabilities. The paper concludes that most special education is supported by nongovernment organizations and that implementation has been restricted by economic constraints.…

  7. Challenges Facing Special Education.

    ERIC Educational Resources Information Center

    Meyen, Edward L., Ed.; And Others

    This book presents 17 selected papers from recent issues of the journal, "Focus on Exceptional Children," concerning current and emerging challenges facing the field of special education. The book is organized in two parts. Part 1, "Contemporary Challenges," includes the following articles: "Transitions in Early Childhood Special Education: Issues…

  8. Preface: ISBB Special Issue

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This special issue is published for the International Society of Biocatalysis and Biotechnology (ISBB). The ISBB special issue is devoted to all areas of biocatalysis and agricultural biotechnology in which biological systems are developed and/or used for the provision of commercial goods or serv...

  9. Special Education in Singapore.

    ERIC Educational Resources Information Center

    Lim, Levan; Nam, Sang Seok

    2000-01-01

    This article describes the development and current status of special education in Singapore. Topics include organization of service delivery, integration, teacher training, and achievements. Challenges to improve the quality of special education services through integration opportunities, preservice teacher training, and greater coordination among…

  10. Special Awareness Month.

    ERIC Educational Resources Information Center

    Granstrom, Jane; And Others

    1982-01-01

    The article reports on the organization and implementation of a "Special Needs Awareness Month" in Quincy, Massachusetts. Noted are the heavy involvement of parents in the multiagency planning committee, and the resulting citywide displays, publications, programs, and publicity on children with special needs. (DB)

  11. Special Education in China.

    ERIC Educational Resources Information Center

    Yang, Hanlin; Wang, HongBo

    1994-01-01

    This article reviews the history and development of special education in China. The historical review covers antiquity to the 1800s, 1800s to 1900s, 1949 to 1965, and 1966 to 1976. Current special education in China is discussed in terms of laws and regulations and major achievements. Major problems and future prospects are also noted. (Author/DB)

  12. Special Education in Turkey

    ERIC Educational Resources Information Center

    Melekoglu, Macid A.; Cakiroglu, Orhan; Malmgren, Kimber W.

    2009-01-01

    Special education has been gaining intense attention from governments and educators throughout the world. As a developing country, and official candidate for the European Union, Turkey has been working on issues related to special education provision and inclusive education to improve the quality of services for citizens with disabilities. This…

  13. Evaluating Special Education Facilities.

    ERIC Educational Resources Information Center

    Elkins, John

    1987-01-01

    The paper discusses early research on evaluating services for Australian disabled persons, the Schonell Evaluation Procedure (SEP) developed for use in Activity Therapy Centres (adult continuing education programs), the modification of SEP for use in special schools for children, and emergent and unmet needs for evaluating adult special education…

  14. Special Education Teacher Persistence

    ERIC Educational Resources Information Center

    Thorp, Sally A.

    2013-01-01

    The focus of this study was special education teachers, who remained in the teaching field 5 or more years. Through the use of qualitative mixed-methods study, variables contributing to their longevity were explored. Research indicates that 50% of special education teachers leave the field within five years of employment (Alliance for Education,…

  15. Assessing Special Events.

    ERIC Educational Resources Information Center

    Neff, Bonita Dostal

    Special events defined as being "newsworthy events" are becoming a way of American life. They are also a means for making a lot of money. Examples of special events that are cited most frequently are often the most minor of events; e.g., the open house, the new business opening day gala, or a celebration of some event in an organization. Little…

  16. Handbook of Special Education.

    ERIC Educational Resources Information Center

    Kauffman, James M., Ed.; Hallahan, Daniel P., Ed.

    Intended to serve as a basic reference work for students and professionals in special education, the book contains 34 author contributed chapters concerned with the conceptual foundations of special education, service delivery systems, curriculum and methods, and child and child/environmental management. Chapters have the following titles and…

  17. Providing Contraception to Adolescents.

    PubMed

    Raidoo, Shandhini; Kaneshiro, Bliss

    2015-12-01

    Adolescents have high rates of unintended pregnancy and face unique reproductive health challenges. Providing confidential contraceptive services to adolescents is important in reducing the rate of unintended pregnancy. Long-acting contraception such as the intrauterine device and contraceptive implant are recommended as first-line contraceptives for adolescents because they are highly effective with few side effects. The use of barrier methods to prevent sexually transmitted infections should be encouraged. Adolescents have limited knowledge of reproductive health and contraceptive options, and their sources of information are often unreliable. Access to contraception is available through a variety of resources that continue to expand. PMID:26598305

  18. The Provident Sea

    NASA Astrophysics Data System (ADS)

    Cushing, David H.

    1988-09-01

    The Provident Sea describes the history of fish stock management (including whales and seals). The book traces, on the basis of the original scientific material, the history of the management of "the provident sea" up to recent times when problems of over-exploitation have had dramatic effects upon stocks. The need for management arose mainly from the increasing industrialization of capture. Hence the preindustrial fisheries are covered, in particular the old cod fishery on the Grand Bank and the herring fishery in the North Sea, as an essential background to current problems. The origins of fisheries and whaling science are described, as is the development up to 1965 of the science and institution in fisheries, whaling, and sealing. In the sixties and seventies, certain major fishing nations took a heavy harvest of fish stocks using sophisticated and efficient gathering methods. This in turn led to conflict and one consequence was the "Law of the Sea" conference set up to try and resolve these issues.

  19. Special and general superatoms.

    PubMed

    Luo, Zhixun; Castleman, A Welford

    2014-10-21

    of application of the jellium model and modification of the theory to account for nonspherical symmetry and nonmetal-doped metal clusters are still illusive to be further developed. It is still worth mentioning that a superatom concept has also been introduced in ligand-stabilized metal clusters which could also follow the major shell-closing electron count for a spherical, square-well potential. By proposing a new concept named as special and general superatoms, herein we try to summarize all these investigations in series, expecting to provide an overview of this field with a primary focus on the joint undertakings which have given rise to the superatom concept. To be specific, for special superatoms, we limit to clusters under a strict jellium model and simply classify them into groups based on their valence electron counts. While for general superatoms we emphasize on nonmetal-doped metal clusters and ligand-stabilized metal clusters, as well as a few isovalent cluster systems. Hopefully this summary of special and general superatoms benefits the further development of cluster-related theory, and lights up the prospect of using them as building blocks of new materials with tailored properties, such as inexpensive isovalent systems for industrial catalysis, semiconductive superatoms for transistors, and magnetic superatoms for spin electronics. PMID:25252219

  20. Specialized Laboratory Information Systems.

    PubMed

    Dangott, Bryan

    2016-03-01

    Some laboratories or laboratory sections have unique needs that traditional anatomic and clinical pathology systems may not address. A specialized laboratory information system (LIS), which is designed to perform a limited number of functions, may perform well in areas where a traditional LIS falls short. Opportunities for specialized LISs continue to evolve with the introduction of new testing methodologies. These systems may take many forms, including stand-alone architecture, a module integrated with an existing LIS, a separate vendor-supplied module, and customized software. This article addresses the concepts underlying specialized LISs, their characteristics, and in what settings they are found. PMID:26851663

  1. What HERA May Provide?

    SciTech Connect

    Jung, Hannes; De Roeck, Albert; Bartels, Jochen; Behnke, Olaf; Blumlein, Johannes; Brodsky, Stanley; Cooper-Sarkar, Amanda; Deak, Michal; Devenish, Robin; Diehl, Markus; Gehrmann, Thomas; Grindhammer, Guenter; Gustafson, Gosta; Khoze, Valery; Knutsson, Albert; Klein, Max; Krauss, Frank; Kutak, Krzysztof; Laenen, Eric; Lonnblad, Leif; Motyka, Leszek; /Hamburg U., Inst. Theor. Phys. II /Birmingham U. /Southern Methodist U. /DESY /Piemonte Orientale U., Novara /CERN /Paris, LPTHE /Hamburg U. /Penn State U.

    2011-11-10

    More than 100 people participated in a discussion session at the DIS08 workshop on the topic What HERA may provide. A summary of the discussion with a structured outlook and list of desirable measurements and theory calculations is given. The HERA accelerator and the HERA experiments H1, HERMES and ZEUS stopped running in the end of June 2007. This was after 15 years of very successful operation since the first collisions in 1992. A total luminosity of {approx} 500 pb{sup -1} has been accumulated by each of the collider experiments H1 and ZEUS. During the years the increasingly better understood and upgraded detectors and HERA accelerator have contributed significantly to this success. The physics program remains in full swing and plenty of new results were presented at DIS08 which are approaching the anticipated final precision, fulfilling and exceeding the physics plans and the previsions of the upgrade program. Most of the analyses presented at DIS08 were still based on the so called HERA I data sample, i.e. data taken until 2000, before the shutdown for the luminosity upgrade. This sample has an integrated luminosity of {approx} 100 pb{sup -1}, and the four times larger statistics sample from HERA II is still in the process of being analyzed.

  2. Special Considerations in Trauma Patients.

    PubMed

    Abraham, Michael K; Aquino, Patrick R; Kuo, Dick C

    2015-11-01

    The emergent management of a traumatic injury can be an extremely intense situation. These assessments can be even more difficult when patients have an underlying psychiatric condition. After a protocoled evaluation of the traumatic injuries, the psychological manifestation of diseases can be addressed. The appropriate use of physical or chemical restraints to facilitate the work-up is paramount in the ability of the provider to protect patients and staff from agitated and traumatized patients. The emergency medicine provider should have a low threshold for including psychiatry in the treatment plans, as the long-term sequelae of these entities require specialized treatment. PMID:26493528

  3. 75 FR 23254 - Office of Special Education and Rehabilitative Services; Overview Information; Training and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-03

    ... Office of Special Education and Rehabilitative Services; Overview Information; Training and Information... work collaboratively with personnel responsible for providing special education, early intervention... at home, including information available through the Office of Special Education Programs'...

  4. Israeli Special Libraries

    ERIC Educational Resources Information Center

    Foster, Barbara

    1974-01-01

    Israel is sprinkled with a noteworthy representation of special libraries which run the gamut from modest kibbutz efforts to highly technical scientific and humanities libraries. A few examples are discussed here. (Author/CH)

  5. Special parallel processing workshop

    SciTech Connect

    1994-12-01

    This report contains viewgraphs from the Special Parallel Processing Workshop. These viewgraphs deal with topics such as parallel processing performance, message passing, queue structure, and other basic concept detailing with parallel processing.

  6. [Diagnostic protocol and special tests].

    PubMed

    Bellia, M; Pennarola, R

    2008-01-01

    Diagnostic protocol and special tests to ionizing radiations have a preventive function in the medical surveillance of the exposed worker. This protocol must be provided with laboratory and special test assessing fitness for working at the risk of ionizing radiations. The health of workers must be compatible with working conditions and radiation risk. This healthiness of workers is evalued in the time to give an assessment fitness for working at ionizing radiations. For this purpose the basic diagnostic protocol must guarantee minimum information about state of organs and apparatus in addition to the normality of the metabolisms. The diagnostic protocol of the exposed worker to ionizing radiations must be adapted to the specific clinical situation so as to finally make a costs-benefits balance sheet. PMID:19288808

  7. A specialization for speech perception.

    PubMed

    Liberman, A M; Mattingly, I G

    1989-01-27

    The processes that underlie perception of consonants and vowels are specifically phonetic, distinct from those that localize sources and assign auditory qualities to the sound from each source. This specialization, or module, increases the rate of information flow, establishes the parity between sender and receiver that every communication system must have, and provides for the natural development of phonetic structures in the species and in the individual. The phonetic module has certain properties in common with modules that are "closed" (for example, sound localization or echo ranging in bats) and, like other members of this class, is so placed in the architecture of the auditory system as to preempt information that is relevant to its special function. Accordingly, this information is not available to such "open" modules as those for pitch, loudness, and timbre. PMID:2643163

  8. State Special Education Finance Systems, 1999-2000. Part II: Special Education Revenues and Expenditures

    ERIC Educational Resources Information Center

    Parrish, Thomas; Harr, Jenifer; Wolman, Jean; Anthony, Jennifer; Merickel, Amy; Esra, Phil

    2004-01-01

    The Center for Special Education Finance (CSEF) provides policymakers and administrators at all governmental levels with data, analyses, expertise, and opportunities to share information about special education finance issues. One of CSEF's major activities is the periodic collection and dissemination of information on state funding systems for…

  9. Rehabilitation Counseling, Special Education, and Vocational Special Needs Education: Three Transition Disciplines.

    ERIC Educational Resources Information Center

    Szymanski, Edna Mora; And Others

    1990-01-01

    The paper explores the involvement of three key professions (rehabilitation counseling, special education, and vocational special needs education) in providing transition services for employment preparation for people with disabilities. Recommendations for a three-level transdisciplinary approach to service delivery are presented. (JDD)

  10. Special Children, Special Care: Early Childhood Education for Children with Disabilities.

    ERIC Educational Resources Information Center

    Illinois State Board of Education, Springfield.

    This manual is a guide to recommended practices and procedures for meeting the special educational needs of young children with disabilities, especially those ages 3 through 5 in Illinois. Chapter 1 provides a brief history of national and Illinois state mandates in early childhood special education, notes the critical role of the family, and…