Sample records for supply ventilation system

  1. Supply Ventilation and Prevention of Carbon Monoxide (II) Ingress into Building Premises

    NASA Astrophysics Data System (ADS)

    Litvinova, N. A.

    2017-11-01

    The article contains the relationships of carbon monoxide (II) concentration versus height-above-ground near buildings derived based on results of studies. The results of studies are crucial in preventing external pollutants ingress into a ventilation system. Being generated by external emission sources, such as motor vehicles and city heating plants, carbon monoxide (II) enters the premises during operation of a supply ventilation system. Fresh air nomographic charts were drawn to select the height of a fresh air intake into the ventilation system. Nomographic charts take into account external sources. The selected emission sources are located at various levels above ground relative to the building. The recommendations allow designing supply ventilation taking into account the quality of ambient air through the whole building height.

  2. [Assessment of energy metabolism and nutritional supply in children with mechanical ventilation].

    PubMed

    Ji, Jian; Qian, Suyun; Yan, Jie

    2016-01-01

    To determine the resting energy expenditure on mechanical ventilation in pediatric intensive care unit (PICU) by indirect calorimetry, and analyze the distribution of metabolic states. The nutrition supply was assessed according to the resting energy expenditure. An observational study which was held in PICU of Beijing Children's Hospital from November 2013 to April 2014. Critically ill children with mechanical ventilation were enrolled in this study. The inclusion criteria included the following: (1) pediatric critical illness score < 90, or meet the United States PICU admission criteria; (2) age > 29 days, < 18 years old; (3) time of mechanical ventilation > 24 hours; (4) volume of mechanical ventilation > 60 ml. Resting energy expenditure was determined by US Med Graphic Company CCM/D energy metabolism test system. Predictive resting energy expenditure was calculated for each subject with age-appropriate equation (Schofield-HTWT). According to the actual energy intake records and required energy intake (10% higher than the measured value) to define the nutritional status. The selected subjects were grouped according to gender, age, types of disease and nutritional status, and compared the metabolic status and nutritional supply of different groups. Sixty-eight children were enrolled in this study, 46 were boys and 22 were girls, including 25 cases of pneumonia with respiratory failure, 23 cases of central nervous system diseases complicated with respiratory failure and 20 cases of postoperative tracheal intubation. The ratio of boys and girls was 2:1. The results showed 36 patients in a low metabolic state, accounting for 53%, 23 patients in a high metabolic state, accounting for 34% and 9 patients (13%) in the metabolism of the normal state. In the male children, 12 cases (26%) were in the high metabolism and 26 cases (57%) were in the low metabolism, and 8 cases (17%) were in the normal metabolism. In the female children, 11 cases (50%) were classified into

  3. Ventilation System Effectiveness and Tested Indoor Air Quality Impacts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rudd, Armin; Bergey, Daniel

    Ventilation system effectiveness testing was conducted at two unoccupied, single-family, detached lab homes at the University of Texas - Tyler. Five ventilation system tests were conducted with various whole-building ventilation systems. Multizone fan pressurization testing characterized building and zone enclosure leakage. PFT testing showed multizone air change rates and interzonal airflow. Cumulative particle counts for six particle sizes, and formaldehyde and other Top 20 VOC concentrations were measured in multiple zones. The testing showed that single-point exhaust ventilation was inferior as a whole-house ventilation strategy. It was inferior because the source of outside air was not direct from outside, themore » ventilation air was not distributed, and no provision existed for air filtration. Indoor air recirculation by a central air distribution system can help improve the exhaust ventilation system by way of air mixing and filtration. In contrast, the supply and balanced ventilation systems showed that there is a significant benefit to drawing outside air from a known outside location, and filtering and distributing that air. Compared to the Exhaust systems, the CFIS and ERV systems showed better ventilation air distribution and lower concentrations of particulates, formaldehyde and other VOCs. System improvement percentages were estimated based on four System Factor Categories: Balance, Distribution, Outside Air Source, and Recirculation Filtration. Recommended System Factors could be applied to reduce ventilation fan airflow rates relative to ASHRAE Standard 62.2 to save energy and reduce moisture control risk in humid climates. HVAC energy savings were predicted to be 8-10%, or $50-$75/year.« less

  4. Ventilation System Effectiveness and Tested Indoor Air Quality Impacts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rudd, Armin; Bergey, Daniel

    In this project, Building America research team Building Science Corporation tested the effectiveness of ventilation systems at two unoccupied, single-family, detached lab homes at the University of Texas - Tyler. Five ventilation system tests were conducted with various whole-building ventilation systems. Multizone fan pressurization testing characterized building and zone enclosure leakage. PFT testing showed multizone air change rates and interzonal airflow. Cumulative particle counts for six particle sizes, and formaldehyde and other Top 20 VOC concentrations were measured in multiple zones. The testing showed that single-point exhaust ventilation was inferior as a whole-house ventilation strategy. This was because the sourcemore » of outside air was not direct from outside, the ventilation air was not distributed, and no provision existed for air filtration. Indoor air recirculation by a central air distribution system can help improve the exhaust ventilation system by way of air mixing and filtration. In contrast, the supply and balanced ventilation systems showed that there is a significant benefit to drawing outside air from a known outside location, and filtering and distributing that air. Compared to the exhaust systems, the CFIS and ERV systems showed better ventilation air distribution and lower concentrations of particulates, formaldehyde and other VOCs. System improvement percentages were estimated based on four system factor categories: balance, distribution, outside air source, and recirculation filtration. Recommended system factors could be applied to reduce ventilation fan airflow rates relative to ASHRAE Standard 62.2 to save energy and reduce moisture control risk in humid climates. HVAC energy savings were predicted to be 8-10%, or $50-$75/year.« less

  5. Technology Solutions Case Study: Ventilation System Effectiveness and Tested Indoor Air Quality Impacts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    A. Rudd and D. Bergey

    Ventilation system effectiveness testing was conducted at two unoccupied, single-family, detached lab homes at the University of Texas - Tyler. Five ventilation system tests were conducted with various whole-building ventilation systems. Multizone fan pressurization testing characterized building and zone enclosure leakage. PFT testing showed multizone air change rates and interzonal airflow filtration. Indoor air recirculation by a central air distribution system can help improve the exhaust ventilation system by way of air mixing and filtration. In contrast, the supply and balanced ventilation systems showed that there is a significant benefit to drawing outside air from a known outside location, andmore » filtering and distributing that air. Compared to the Exhaust systems, the CFIS and ERV systems showed better ventilation air distribution and lower concentrations of particulates, formaldehyde and other VOCs.« less

  6. WASTE HANDLING BUILDING VENTILATION SYSTEM DESCRIPTION DOCUMENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    P.A. Kumar

    2000-06-21

    reasonably achievable) principles to maintain personnel radiation doses to all occupational workers below regulatory limits and as low as is reasonably achievable. The Waste Handling Building Ventilation System interfaces with the Waste Handling Building System by being located within the WHB and by maintaining specific pressures, temperatures, and humidity within the building. The system also depends on the WHB for water supply. The system interfaces with the Site Radiological Monitoring System for continuous monitoring of the exhaust air; the Waste Handling Building Fire Protection System for detection of fire and smoke; the Waste Handling Building Electrical System for normal, emergency, and standby power; and the Monitored Geologic Repository Operations Monitoring and Control System for monitoring and control of the system.« less

  7. 46 CFR 111.103-1 - Power ventilation systems except machinery space ventilation systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Remote Stopping Systems § 111.103-1 Power ventilation systems except machinery space ventilation systems. Each power ventilation system must... 46 Shipping 4 2010-10-01 2010-10-01 false Power ventilation systems except machinery space...

  8. 46 CFR 111.103-1 - Power ventilation systems except machinery space ventilation systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Remote Stopping Systems § 111.103-1 Power ventilation systems except machinery space ventilation systems. Each power ventilation system must... 46 Shipping 4 2011-10-01 2011-10-01 false Power ventilation systems except machinery space...

  9. 46 CFR 111.103-1 - Power ventilation systems except machinery space ventilation systems.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Remote Stopping Systems § 111.103-1 Power ventilation systems except machinery space ventilation systems. Each power ventilation system must... 46 Shipping 4 2014-10-01 2014-10-01 false Power ventilation systems except machinery space...

  10. 46 CFR 111.103-1 - Power ventilation systems except machinery space ventilation systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Remote Stopping Systems § 111.103-1 Power ventilation systems except machinery space ventilation systems. Each power ventilation system must... 46 Shipping 4 2012-10-01 2012-10-01 false Power ventilation systems except machinery space...

  11. 46 CFR 111.103-1 - Power ventilation systems except machinery space ventilation systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Remote Stopping Systems § 111.103-1 Power ventilation systems except machinery space ventilation systems. Each power ventilation system must... 46 Shipping 4 2013-10-01 2013-10-01 false Power ventilation systems except machinery space...

  12. 46 CFR 154.1200 - Mechanical ventilation system: General.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... gas-safe space in the cargo area. (4) Each space that contains inert gas generators, except main...) Each cargo compressor room, pump room, gas-dangerous cargo control station, and space that contains... following must have a supply-type mechanical ventilation system: (1) Each space that contains electric...

  13. Potential risk for bacterial contamination in conventional reused ventilator systems and disposable closed ventilator-suction systems.

    PubMed

    Li, Ya-Chi; Lin, Hui-Ling; Liao, Fang-Chun; Wang, Sing-Siang; Chang, Hsiu-Chu; Hsu, Hung-Fu; Chen, Sue-Hsien; Wan, Gwo-Hwa

    2018-01-01

    Few studies have investigated the difference in bacterial contamination between conventional reused ventilator systems and disposable closed ventilator-suction systems. The aim of this study was to investigate the bacterial contamination rates of the reused and disposable ventilator systems, and the association between system disconnection and bacterial contamination of ventilator systems. The enrolled intubated and mechanically ventilated patients used a conventional reused ventilator system and a disposable closed ventilator-suction system, respectively, for a week; specimens were then collected from the ventilator circuit systems to evaluate human and environmental bacterial contamination. The sputum specimens from patients were also analyzed in this study. The detection rate of bacteria in the conventional reused ventilator system was substantially higher than that in the disposable ventilator system. The inspiratory and expiratory limbs of the disposable closed ventilator-suction system had higher bacterial concentrations than the conventional reused ventilator system. The bacterial concentration in the heated humidifier of the reused ventilator system was significantly higher than that in the disposable ventilator system. Positive associations existed among the bacterial concentrations at different locations in the reused and disposable ventilator systems, respectively. The predominant bacteria identified in the reused and disposable ventilator systems included Acinetobacter spp., Bacillus cereus, Elizabethkingia spp., Pseudomonas spp., and Stenotrophomonas (Xan) maltophilia. Both the reused and disposable ventilator systems had high bacterial contamination rates after one week of use. Disconnection of the ventilator systems should be avoided during system operation to decrease the risks of environmental pollution and human exposure, especially for the disposable ventilator system. ClinicalTrials.gov PRS / NCT03359148.

  14. Potential risk for bacterial contamination in conventional reused ventilator systems and disposable closed ventilator-suction systems

    PubMed Central

    Li, Ya-Chi; Lin, Hui-Ling; Liao, Fang-Chun; Wang, Sing-Siang; Chang, Hsiu-Chu; Hsu, Hung-Fu; Chen, Sue-Hsien

    2018-01-01

    Background Few studies have investigated the difference in bacterial contamination between conventional reused ventilator systems and disposable closed ventilator-suction systems. The aim of this study was to investigate the bacterial contamination rates of the reused and disposable ventilator systems, and the association between system disconnection and bacterial contamination of ventilator systems. Methods The enrolled intubated and mechanically ventilated patients used a conventional reused ventilator system and a disposable closed ventilator-suction system, respectively, for a week; specimens were then collected from the ventilator circuit systems to evaluate human and environmental bacterial contamination. The sputum specimens from patients were also analyzed in this study. Results The detection rate of bacteria in the conventional reused ventilator system was substantially higher than that in the disposable ventilator system. The inspiratory and expiratory limbs of the disposable closed ventilator-suction system had higher bacterial concentrations than the conventional reused ventilator system. The bacterial concentration in the heated humidifier of the reused ventilator system was significantly higher than that in the disposable ventilator system. Positive associations existed among the bacterial concentrations at different locations in the reused and disposable ventilator systems, respectively. The predominant bacteria identified in the reused and disposable ventilator systems included Acinetobacter spp., Bacillus cereus, Elizabethkingia spp., Pseudomonas spp., and Stenotrophomonas (Xan) maltophilia. Conclusions Both the reused and disposable ventilator systems had high bacterial contamination rates after one week of use. Disconnection of the ventilator systems should be avoided during system operation to decrease the risks of environmental pollution and human exposure, especially for the disposable ventilator system. Trial registration Clinical

  15. Definition and means of maintaining the supply ventilation system seismic shutdown portion of the PFP safety envelope

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Keck, R.D.

    1997-01-21

    The purpose of this document is to record the technical evaluation of the Limiting Condition for Operation (LCO) described in the Plutonium Finishing Plant (PFP) Operational Safety Requirements, WHC-SD-CP-OSR- 010, Rev. 0. Kay 1994, Section 3.2.3, `Supply Ventilation System Seismic Shutdown.` This document, with its appendices, provides the following: 1. The system functional requirements for determining system operability (Section 3). 2. Evaluations of equipment to determine the safety boundary for the system (Section 4). 3. A list of annotated drawings which show the safety envelope boundaries (Appendix C). 4. A list of the safety envelope equipment (Appendix B). 5. Functionalmore » requirements for the individual safety envelope equipment, including appropriate setpoints and process parameters (Section 4.1). 6. A list of the operational, maintenance and surveillance procedures necessary to operate and maintain the system equipment within the safety envelope (Sections 5 and 6 and Appendix A).« less

  16. Ventilation.

    PubMed

    Turner, W A; Bearg, D W; Brennan, T

    1995-01-01

    This chapter begins with an overview of the history of ventilation guidelines, which has led to the guidelines that are in effect today. Of particular interest is the most recent return in the past 5 years to ventilation rates that more closely reflect a mean or average of the range of guidelines that have existed over the past century. OSHA's and the EPA's recognition of the need to operate ventilation systems in buildings in an accountable manner is also of note. Of even more interest is the resurgence of the concept of minimum mixing and once-through ventilation air that has been pursued in parts of Northern Europe for the past 10 years, and in a school that is being designed with this concept in New Hampshire. In addition, the design concept of equipping office buildings with low pressure drop high efficiency particle filtration to remove fine particles from all of the air that is supplied to the occupants is being used increasingly in the U.S. This chapter also presents an overview of the various types of ventilation systems found in homes and commercial office buildings and the common indoor air quality problems that may be associated with them. It also offers an overview of common HVAC evaluation techniques that can be used to determine if a ventilation system is performing in a manner that makes sense for the use of the space and the needs of the occupants. Are the occupants receiving a reasonable supply of outdoor air? Is the air that they receive of reasonable quality? Are obvious pollutants being exhausted? Ventilation systems have become extremely complex and more difficult to run and maintain over the past 40 years. This trend will continue to drive the need for professionally maintained HVAC equipment that is serviced and run by individuals who are accountable for the quality of the air that the system delivers.

  17. Interactive simulation system for artificial ventilation on the internet: virtual ventilator.

    PubMed

    Takeuchi, Akihiro; Abe, Tadashi; Hirose, Minoru; Kamioka, Koichi; Hamada, Atsushi; Ikeda, Noriaki

    2004-12-01

    To develop an interactive simulation system "virtual ventilator" that demonstrates the dynamics of pressure and flow in the respiratory system under the combination of spontaneous breathing, ventilation modes, and ventilator options. The simulation system was designed to be used by unexperienced health care professionals as a self-training tool. The system consists of a simulation controller and three modules: respiratory, spontaneous breath, and ventilator. The respiratory module models the respiratory system by three resistances representing the main airway, the right and left lungs, and two compliances also representing the right and left lungs. The spontaneous breath module generates inspiratory negative pressure produced by a patient. The ventilator module generates driving force of pressure or flow according to the combination of the ventilation mode and options. These forces are given to the respiratory module through the simulation controller. The simulation system was developed using HTML, VBScript (3000 lines, 100 kB) and ActiveX control (120 kB), and runs on Internet Explorer (5.5 or higher). The spontaneous breath is defined by a frequency, amplitude and inspiratory patterns in the spontaneous breath module. The user can construct a ventilation mode by setting a control variable, phase variables (trigger, limit, and cycle), and options. Available ventilation modes are: controlled mechanical ventilation (CMV), continuous positive airway pressure, synchronized intermittent mandatory ventilation (SIMV), pressure support ventilation (PSV), SIMV + PSV, pressure-controlled ventilation (PCV), pressure-regulated volume control (PRVC), proportional assisted ventilation, mandatory minute ventilation (MMV), bilevel positive airway pressure (BiPAP). The simulation system demonstrates in a graph and animation the airway pressure, flow, and volume of the respiratory system during mechanical ventilation both with and without spontaneous breathing. We developed a web

  18. 46 CFR 111.103-3 - Machinery space ventilation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Machinery space ventilation. 111.103-3 Section 111.103-3...-GENERAL REQUIREMENTS Remote Stopping Systems § 111.103-3 Machinery space ventilation. (a) Each machinery space ventilation system must have two controls to stop the ventilation, one of which may be the supply...

  19. 46 CFR 111.103-3 - Machinery space ventilation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Machinery space ventilation. 111.103-3 Section 111.103-3...-GENERAL REQUIREMENTS Remote Stopping Systems § 111.103-3 Machinery space ventilation. (a) Each machinery space ventilation system must have two controls to stop the ventilation, one of which may be the supply...

  20. 46 CFR 111.103-3 - Machinery space ventilation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Machinery space ventilation. 111.103-3 Section 111.103-3...-GENERAL REQUIREMENTS Remote Stopping Systems § 111.103-3 Machinery space ventilation. (a) Each machinery space ventilation system must have two controls to stop the ventilation, one of which may be the supply...

  1. 46 CFR 111.103-3 - Machinery space ventilation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Machinery space ventilation. 111.103-3 Section 111.103-3...-GENERAL REQUIREMENTS Remote Stopping Systems § 111.103-3 Machinery space ventilation. (a) Each machinery space ventilation system must have two controls to stop the ventilation, one of which may be the supply...

  2. 46 CFR 111.103-3 - Machinery space ventilation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Machinery space ventilation. 111.103-3 Section 111.103-3...-GENERAL REQUIREMENTS Remote Stopping Systems § 111.103-3 Machinery space ventilation. (a) Each machinery space ventilation system must have two controls to stop the ventilation, one of which may be the supply...

  3. [Hygienic Inspections of Ventilation Systems Under Resting Conditions (According to DIN 1946-4:1999-03) - A Retrospective Assessment].

    PubMed

    Friedrich, Lena; Boeckelmann, Irina

    2018-01-11

    Hygienic and microbiologically sterile air quality is essential for successful guideline-based work in operating theatres. To ensure clean air and to reduce contamination during surgery, ventilation systems are indispensable. Ventilation systems should be especially designed to keep the number of particles and germs under statutory limits. Therefore, they must be operated to recognised standards of good practice and be periodically inspected and maintained. The objective of this study was to prove, through the analysis of observation outside surgery time (rest condition), the effects of ventilation systems on air quality in a medical facility. Measurements were taken in 34 operating theatres annually over a period of ten years outside surgery time (resting condition) but with the air ventilation system operating under full load. 29 operating theatres were provided with laminar air flow and five theatres with turbulent air flow systems. In each operating theatre, air cleanliness was analysed by measuring the amount of airborne particles and airborne germs. Measuring points were determined 10 mm beneath the supply-air ceiling in the centre of the operating theatre and at one position outside the supply-air ceiling. The number of airborne particles at the supply-air ceiling was between 0/m³ and 4,441/m³ of air and, as such, the limiting factor was never exceeded. However, airborne germ measurements of between 0 CFU/m³ and 200 CFU/m³ (CFU: colony forming units) demonstrated that the limiting factor for this criterion was exceeded in 10.9% of occasions. In general, the values in the middle of the room were higher than at the supply-air ceiling. There were significant differences (p < 0.001) between the values at the supply-air ceiling, the surgery table and the values outside the supply-air ceiling. The results show the positive impact of ventilation systems on the air cleanliness in operating theatres. However, laminar airflow systems seem to create cleaner

  4. Multifamily Individual Heating and Ventilation Systems, Lawrence, Massachusetts (Fact Sheet)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    The conversion of an older Massachusetts building into condominiums illustrates a safe, durable, and cost-effective solution for heating and ventilation systems that can potentially benefit millions of multifamily buildings. Merrimack Valley Habitat for Humanity (MVHfH) partnered with U.S. Department of Energy Building America team Building Science Corporation (BSC) to provide high performance affordable housing for 10 families in the retrofit of an existing mass masonry building (a former convent). The original ventilation design for the project was provided by a local engineer and consisted of a single large heat recovery ventilator (HRV) located in a mechanical room in the basementmore » with a centralized duct system providing supply air to the main living space and exhausting stale air from the single bathroom in each apartment. This design was deemed to be far too costly to install and operate for several reasons: the large central HRV was oversized and the specified flows to each apartment were much higher than the ASHRAE 62.2 rate; an extensive system of ductwork, smoke and fire dampers, and duct chases were specified; ductwork required a significant area of dropped ceilings; and the system lacked individual ventilation control in the apartments« less

  5. Building America Case Study: Ventilation System Effectiveness and Tested Indoor Air Quality Impacts, Tyler, Texas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    ?Ventilation system effectiveness testing was conducted at two unoccupied, single-family, detached lab homes at the University of Texas - Tyler. Five ventilation system tests were conducted with various whole-building ventilation systems. Multizone fan pressurization testing characterized building and zone enclosure leakage. PFT testing showed multizone air change rates and interzonal airflow filtration. Indoor air recirculation by a central air distribution system can help improve the exhaust ventilation system by way of air mixing and filtration. In contrast, the supply and balanced ventilation systems showed that there is a significant benefit to drawing outside air from a known outside location, andmore » filtering and distributing that air. Compared to the Exhaust systems, the CFIS and ERV systems showed better ventilation air distribution and lower concentrations of particulates, formaldehyde and other VOCs. System improvement percentages were estimated based on four System Factor Categories: Balance, Distribution, Outside Air Source, and Recirculation Filtration. Recommended System Factors could be applied to reduce ventilation fan airflow rates relative to ASHRAE Standard 62.2 to save energy and reduce moisture control risk in humid climates. HVAC energy savings were predicted to be 8-10%, or $50-$75/year. Cumulative particle counts for six particle sizes, and formaldehyde and other Top 20 VOC concentrations were measured in multiple zones. The testing showed that single-point exhaust ventilation was inferior as a whole-house ventilation strategy.« less

  6. VENTILATION TECHNOLOGY SYSTEMS ANALYSIS

    EPA Science Inventory

    The report gives results of a project to develop a systems analysis of ventilation technology and provide a state-of-the-art assessment of ventilation and indoor air quality (IAQ) research needs. (NOTE: Ventilation technology is defined as the hardware necessary to bring outdoor ...

  7. Demand controlled ventilating systems: Sensor market survey. Energy conservation in buildings and community systems programme, annex 18, December 1991

    NASA Astrophysics Data System (ADS)

    Raatschen, W.; Sjoegren, M.

    The subject of indoor and outdoor air quality has generated a great deal of attention in many countries. Areas of concern include outgassing of building materials as well as occupant-generated pollutants such as carbon dioxide, moisture, and odors. Progress has also been made towards addressing issues relating to the air tightness of the building envelope. Indoor air quality studies indicate that better control of supply flow rates as well as the air distribution pattern within buildings are necessary. One method of maintaining good indoor air quality without extensive energy consumption is to control the ventilation rate according to the needs and demands of the occupants, or to preserve the building envelope. This is accomplished through the use of demand controlled ventilating (DCV) systems. The specific objective of Annex 18 is to develop guidelines for demand controlled ventilating systems based on state of the art analyses, case studies on ventilation effectiveness, and proposed ventilation rates for different users in domestic, office, and school buildings.

  8. 33 CFR 183.620 - Natural ventilation system.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Natural ventilation system. 183... (CONTINUED) BOATING SAFETY BOATS AND ASSOCIATED EQUIPMENT Ventilation § 183.620 Natural ventilation system. (a) Except for compartments open to the atmosphere, a natural ventilation system that meets the...

  9. 33 CFR 183.620 - Natural ventilation system.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Natural ventilation system. 183... (CONTINUED) BOATING SAFETY BOATS AND ASSOCIATED EQUIPMENT Ventilation § 183.620 Natural ventilation system. (a) Except for compartments open to the atmosphere, a natural ventilation system that meets the...

  10. Energy saving effect of desiccant ventilation system using Wakkanai siliceous shale

    NASA Astrophysics Data System (ADS)

    Nabeshima, Yuki; Togawa, Jun-ya; Nagano, Katsunori; Kazuyo, Tsuzuki

    2017-10-01

    The nuclear power station accident resulting from the Great East Japan Earthquake disaster has resulted in a constrained electricity supply. However, in this Asian region there is high temperature and high humidity and consequently dehumidification process requires a huge amount of energy. This is the reason for the increasing energy consumption in the residential and commercial sectors. Accordingly, a high efficiency air-conditioning system is needed to be developed. The desiccant ventilation system is effective to reduce energy consumption for the dehumidification process. This system is capable of dehumidifying without dew condensing unlike a conventional air-conditioning system. Then we focused on Wakkanai Siliceous Shale (WSS) as a desiccant material to develop a new desiccant ventilation system. This is low priced, high performance, new type of thing. The aim of this study is to develop a desiccant ventilation unit using the WSS rotor which can be regenerated with low-temperature by numerical calculation. The results of performance prediction of the desiccant unit, indicate that it is possible to regenerate the WSS rotor at low-temperature of between 35 - 45 °C. In addition, we produced an actual measurement for the desiccant unit and air-conditioning unit. This air-conditioning system was capable to reduce roughly 40 % of input energy consumption.

  11. Proportional assist ventilation system based on proportional solenoid valve control.

    PubMed

    Lua, A C; Shi, K C; Chua, L P

    2001-07-01

    A new proportional assist ventilation (PAV) method using a proportional solenoid valve (PSV) to control air supply to patients suffering from respiratory disabilities, was studied. The outlet flow and pressure from the proportional solenoid valve at various air supply pressures were tested and proven to be suitable for pressure and flow control in a PAV system. In vitro tests using a breathing simulator, which has been proven to possess the general characteristics of human respiratory system in spontaneous breathing tests, were conducted and the results demonstrated the viability of this PAV system in normalizing the breathing patterns of patients with abnormally high resistances and elastances as well as neuromuscular weaknesses. With a back-up safety mechanism incorporated in the control program, pressure "run-away" can be effectively prevented and safe operation of the system can be guaranteed.

  12. Protective garment ventilation system

    NASA Technical Reports Server (NTRS)

    Lang, R. (Inventor)

    1970-01-01

    A method and apparatus for ventilating a protective garment, space suit system, and/or pressure suits to maintain a comfortable and nontoxic atmosphere within is described. The direction of flow of a ventilating and purging gas in portions of the garment may be reversed in order to compensate for changes in environment and activity of the wearer. The entire flow of the ventilating gas can also be directed first to the helmet associated with the garment.

  13. 46 CFR 154.1200 - Mechanical ventilation system: General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Mechanical ventilation system: General. 154.1200 Section... Equipment Cargo Area: Mechanical Ventilation System § 154.1200 Mechanical ventilation system: General. (a... cargo handling equipment must have a fixed, exhaust-type mechanical ventilation system. (b) The...

  14. 46 CFR 154.1205 - Mechanical ventilation system: Standards.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Mechanical ventilation system: Standards. 154.1205... Equipment Cargo Area: Mechanical Ventilation System § 154.1205 Mechanical ventilation system: Standards. (a) Each exhaust type mechanical ventilation system required under § 154.1200 (a) must have ducts for...

  15. [Optimal energy supply in different age groups of critically ill children on mechanical ventilation].

    PubMed

    Li, X H; Ji, J; Qian, S Y

    2018-01-02

    Objective: To analyze the resting energy expenditure and optimal energy supply in different age groups of critically ill children on mechanical ventilation in pediatric intensive care unit (PICU). Methods: Patients on mechanical ventilation hospitalized in PICU of Beijing Children's Hospital from March 2015 to March 2016 were enrolled prospectively. Resting energy expenditure of patients was calculated by US Med Graphic company critical care management (CCM) energy metabolism test system after mechanical ventilation. Patients were divided into three groups:<3 years, 3-10 years, and >10 years. The relationship between the measured and predictive resting energy expenditure was analyzed with correlation analysis; while the metabolism status and the optimal energy supply in different age groups were analyzed with chi square test and variance analysis. Results: A total of 102 patients were enrolled, the measured resting energy expenditure all correlated with predictive resting energy expenditure in different age groups (<3 years ( r= 0.3, P= 0.0) ; 3~10 years ( r= 0.6, P= 0.0) ;>10 years ( r= 0.5, P= 0.0) ) . A total of 40 cases in < 3 years group, including: 14 cases of low metabolism (35%), 14 cases of normal metabolism (35%), and 12 cases of high metabolism (30%); 45 cases in 3-10 years group, including: 22 cases of low metabolism (49%), 19 cases of normal metabolism (42%), 4 cases of high metabolism (9%); 17 cases in > 10 years group, including: 12 cases of low metabolism (71%), 4 cases of normal metabolism (23%), 1 case of high metabolism (6%). Metabolism status showed significant differences between different age groups ( χ (2)=11.30, P <0.01, r= -0.01). Infants had higher metabolic status, which lessened with aging. The total average actual energy requirement was (210±84) kJ/ (kg⋅d) . There were significant differences in actual energy requirement between age groups ( F= 46.57, P< 0.001), with (277±77) kJ/ (kg⋅d) in < 3 years group, (184±53) kJ/ (kg

  16. Automatic Electronic Oxygen Supply

    PubMed Central

    Ford, Patricia; Hoodless, D. J.

    1971-01-01

    An automatic electronic oxygen system has been devised to supply an intensive care unit with a “fail-safe” supply of continuous oxygen. All parts of the system are fitted with alarms, as the oxygen powers gas-driven ventilators. Since the system is cheap it can be installed in hospitals where finance is limited. PMID:5278618

  17. A new system for understanding modes of mechanical ventilation.

    PubMed

    Chatburn, R L; Primiano, F P

    2001-06-01

    Numerous ventilation modes and ventilation options have become available as new mechanical ventilators have reached the market. Ventilator manufacturers have no standardized terminology for ventilator modes and ventilation options, and ventilator operator's manuals do not help the clinician compare the modes of ventilators from different manufacturers. This article proposes a standardized system for classifying ventilation modes, based on general engineering principles and a small set of explicit definitions. Though there may be resistance by ventilator manufacturers to a standardized system of ventilation terminology, clinicians and health care equipment purchasers should adopt such a system in the interest of clear communication--the lack of which prevents clinicians from fully understanding the therapies they administer and could compromise the quality of patient care.

  18. 46 CFR 153.312 - Ventilation system standards.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Handling Space Ventilation § 153.312 Ventilation system standards. A cargo handling space ventilation... (approx. 32.8 ft) from openings into or ventilation intakes for, accommodation or service spaces. (b) A...

  19. 46 CFR 153.312 - Ventilation system standards.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Handling Space Ventilation § 153.312 Ventilation system standards. A cargo handling space ventilation... (approx. 32.8 ft) from openings into or ventilation intakes for, accommodation or service spaces. (b) A...

  20. 46 CFR 153.312 - Ventilation system standards.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Handling Space Ventilation § 153.312 Ventilation system standards. A cargo handling space ventilation... (approx. 32.8 ft) from openings into or ventilation intakes for, accommodation or service spaces. (b) A...

  1. 46 CFR 153.312 - Ventilation system standards.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Handling Space Ventilation § 153.312 Ventilation system standards. A cargo handling space ventilation... (approx. 32.8 ft) from openings into or ventilation intakes for, accommodation or service spaces. (b) A...

  2. 46 CFR 153.312 - Ventilation system standards.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Handling Space Ventilation § 153.312 Ventilation system standards. A cargo handling space ventilation... (approx. 32.8 ft) from openings into or ventilation intakes for, accommodation or service spaces. (b) A...

  3. 14 CFR 252.9 - Ventilation systems.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Ventilation systems. 252.9 Section 252.9 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS SMOKING ABOARD AIRCRAFT § 252.9 Ventilation systems. Air carriers shall prohibit smoking whenever...

  4. 14 CFR 252.9 - Ventilation systems.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Ventilation systems. 252.9 Section 252.9 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS SMOKING ABOARD AIRCRAFT § 252.9 Ventilation systems. Air carriers shall prohibit smoking whenever...

  5. 14 CFR 252.9 - Ventilation systems.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Ventilation systems. 252.9 Section 252.9 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS SMOKING ABOARD AIRCRAFT § 252.9 Ventilation systems. Air carriers shall prohibit smoking whenever...

  6. 14 CFR 252.9 - Ventilation systems.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Ventilation systems. 252.9 Section 252.9 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS SMOKING ABOARD AIRCRAFT § 252.9 Ventilation systems. Air carriers shall prohibit smoking whenever...

  7. 14 CFR 252.9 - Ventilation systems.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Ventilation systems. 252.9 Section 252.9 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS SMOKING ABOARD AIRCRAFT § 252.9 Ventilation systems. Air carriers shall prohibit smoking whenever...

  8. Advanced Hybrid Spacesuit Concept Featuring Integrated Open Loop and Closed Loop Ventilation Systems

    NASA Technical Reports Server (NTRS)

    Daniel, Brian A.; Fitzpatrick, Garret R.; Gohmert, Dustin M.; Ybarra, Rick M.; Dub, Mark O.

    2013-01-01

    A document discusses the design and prototype of an advanced spacesuit concept that integrates the capability to function seamlessly with multiple ventilation system approaches. Traditionally, spacesuits are designed to operate both dependently and independently of a host vehicle environment control and life support system (ECLSS). Spacesuits that operate independent of vehicle-provided ECLSS services must do so with equipment selfcontained within or on the spacesuit. Suits that are dependent on vehicle-provided consumables must remain physically connected to and integrated with the vehicle to operate properly. This innovation is the design and prototype of a hybrid spacesuit approach that configures the spacesuit to seamlessly interface and integrate with either type of vehicular systems, while still maintaining the ability to function completely independent of the vehicle. An existing Advanced Crew Escape Suit (ACES) was utilized as the platform from which to develop the innovation. The ACES was retrofitted with selected components and one-off items to achieve the objective. The ventilation system concept was developed and prototyped/retrofitted to an existing ACES. Components were selected to provide suit connectors, hoses/umbilicals, internal breathing system ducting/ conduits, etc. The concept utilizes a lowpressure- drop, high-flow ventilation system that serves as a conduit from the vehicle supply into the suit, up through a neck seal, into the breathing helmet cavity, back down through the neck seal, out of the suit, and returned to the vehicle. The concept also utilizes a modified demand-based breathing system configured to function seamlessly with the low-pressure-drop closed-loop ventilation system.

  9. Measured performance of filtration and ventilation systems for fine and ultrafine particles and ozone in an unoccupied modern California house.

    PubMed

    Singer, B C; Delp, W W; Black, D R; Walker, I S

    2017-07-01

    This study evaluated nine ventilation and filtration systems in an unoccupied 2006 house located 250 m downwind of the I-80 freeway in Sacramento, California. Systems were evaluated for reducing indoor concentrations of outdoor particles in summer and fall/winter, ozone in summer, and particles from stir-fry cooking. Air exchange rate was measured continuously. Energy use was estimated for year-round operation in California. Exhaust ventilation without enhanced filtration provided indoor PM 2.5 that was 70% lower than outdoors. Supply ventilation with MERV13 filtration provided slightly less protection, whereas supply MERV16 filtration reduced PM 2.5 by 97-98% relative to outdoors. Supply filtration systems used little energy but provided no benefits for indoor-generated particles. Systems with MERV13-16 filter in the recirculating heating and cooling unit (FAU) operating continuously or 20 min/h reduced PM 2.5 by 93-98%. Across all systems, removal percentages were higher for ultrafine particles and lower for black carbon, relative to PM 2.5 . Indoor ozone was 3-4% of outdoors for all systems except an electronic air cleaner that produced ozone. Filtration via the FAU or portable filtration units lowered PM 2.5 by 25-75% when operated over the hour following cooking. The energy for year-round operation of FAU filtration with an efficient blower motor was estimated at 600 kWh/year. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  10. Measured performance of filtration and ventilation systems for fine and ultrafine particles and ozone in an unoccupied modern California house

    DOE PAGES

    Singer, B. C.; Delp, W. W.; Black, D. R.; ...

    2016-12-05

    This study evaluated nine ventilation and filtration systems in an unoccupied 2006 house located 250 m downwind of the I-80 freeway in Sacramento, California. Systems were evaluated for reducing indoor concentrations of outdoor particles in summer and fall/winter, ozone in summer, and particles from stir-fry cooking. Air exchange rate was measured continuously. Energy use was estimated for year-round operation in California. Exhaust ventilation without enhanced filtration provided indoor PM 2.5 that was 70% lower than outdoors. Supply ventilation with MERV13 filtration provided slightly less protection, whereas supply MERV16 filtration reduced PM 2.5 by 97-98% relative to outdoors. Supply filtration systems usedmore » little energy but provided no benefits for indoor-generated particles. Systems with MERV13-16 fil ter in the recirculating heating and cooling unit (FAU) operating continuously or 20 min/h reduced PM 2.5 by 93-98%. Across all systems, removal percentages were higher for ultrafine particles and lower for black carbon, relative to PM 2.5 . Indoor ozone was 3-4% of outdoors for all systems except an electronic air cleaner that produced ozone. Filtration via the FAU or portable filtration units lowered PM 2.5 by 25-75% when operated over the hour following cooking. The energy for year-round operation of FAU filtration with an efficient blower motor was estimated at 600 kWh/year.« less

  11. Measured performance of filtration and ventilation systems for fine and ultrafine particles and ozone in an unoccupied modern California house

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Singer, Brett C.; Delp, William W.; Black, Douglas R.

    This study evaluated nine ventilation and filtration systems in an unoccupied 2006 house located 250m downwind of the I-80 freeway in Sacramento, California. Systems were evaluated for reducing indoor concentrations of outdoor particles in summer and fall/winter, ozone in summer, and particles from stir-fry cooking. Air exchange rate was measured continuously. Energy use was estimated for year-round operation in California. Exhaust ventilation without enhanced filtration produced indoor PM 2.5 that was 70% lower than outdoors. Supply ventilation with MERV13 filtration provided slightly less protection whereas supply MERV16 filtration reduced PM 2.55 by 97-98% relative to outdoors. Supply filtration systems usedmore » little energy but provided no benefits for indoor-generated particles. Systems with MERV13-16 filters in the recirculating heating and cooling unit (FAU) operating continuously or 20 min/h reduced PM 2.5 by 93-98%. Across all systems, removal percentages were higher for ultrafine particles and lower for black carbon, relative to PM 2.5. Indoor ozone was 3-4% of outdoors for all systems except an electronic air cleaner that produced ozone. Filtration via the FAU or portable filtration units lowered PM 2.5 by 25-75% when operated over the hour following cooking. The energy for year-round operation of FAU filtration with an efficient blower motor was estimated at 600 kWh/year.« less

  12. Measured performance of filtration and ventilation systems for fine and ultrafine particles and ozone in an unoccupied modern California house

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Singer, B. C.; Delp, W. W.; Black, D. R.

    This study evaluated nine ventilation and filtration systems in an unoccupied 2006 house located 250 m downwind of the I-80 freeway in Sacramento, California. Systems were evaluated for reducing indoor concentrations of outdoor particles in summer and fall/winter, ozone in summer, and particles from stir-fry cooking. Air exchange rate was measured continuously. Energy use was estimated for year-round operation in California. Exhaust ventilation without enhanced filtration provided indoor PM 2.5 that was 70% lower than outdoors. Supply ventilation with MERV13 filtration provided slightly less protection, whereas supply MERV16 filtration reduced PM 2.5 by 97-98% relative to outdoors. Supply filtration systems usedmore » little energy but provided no benefits for indoor-generated particles. Systems with MERV13-16 fil ter in the recirculating heating and cooling unit (FAU) operating continuously or 20 min/h reduced PM 2.5 by 93-98%. Across all systems, removal percentages were higher for ultrafine particles and lower for black carbon, relative to PM 2.5 . Indoor ozone was 3-4% of outdoors for all systems except an electronic air cleaner that produced ozone. Filtration via the FAU or portable filtration units lowered PM 2.5 by 25-75% when operated over the hour following cooking. The energy for year-round operation of FAU filtration with an efficient blower motor was estimated at 600 kWh/year.« less

  13. Laboratory and Industrial Ventilation

    NASA Technical Reports Server (NTRS)

    1972-01-01

    This handbook supplements the Facilities Engineering Handbook (NHB 7320.1) and provides additional policies and criteria for uniform application to ventilation systems. It expands basic requirements, provides additional design and construction guidance, and places emphasis on those design considerations which will provide for greater effectiveness in the use of these systems. The provisions of this handbook are applicable to all NASA field installations and the Jet Propulsion Laboratory. Since supply of this handbook is limited, abstracts of the portion or portions applicable to a given requirement will be made for the individual specific needs encountered rather than supplying copies of the handbook as has been past practice.

  14. Occupational exposure to nitrous oxide - the role of scavenging and ventilation systems in reducing the exposure level in operating rooms.

    PubMed

    Krajewski, Wojciech; Kucharska, Malgorzata; Wesolowski, Wiktor; Stetkiewicz, Jan; Wronska-Nofer, Teresa

    2007-03-01

    The aim of this study was to assess the level of occupational exposure to nitrous oxide (N(2)O) in operating rooms (ORs), as related to different ventilation and scavenging systems used to remove waste anaesthetic gases from the work environment. The monitoring of N(2)O in the air covered 35 ORs in 10 hospitals equipped with different systems for ventilation and anaesthetic scavenging. The examined systems included: natural ventilation with supplementary fresh air provided by a pressure ventilation system (up to 6 air changes/h); pressure and exhaust ventilation systems equipped with ventilation units supplying fresh air to and discharging contaminated air outside the working area (more than 10 air changes/h); complete air-conditioning system with laminar air flow (more than 15 air changes/h). The measurements were carried out during surgical procedures (general anaesthesia induced intravenously and maintained with inhaled N(2)O and sevofluran delivered through cuffed endotracheal tubes) with connected or disconnected air scavenging. Air was collected from the breathing zone of operating personnel continuously through the whole time of anaesthesia to Tedlar((R)) bags, and N(2)O concentrations in air samples were analyzed by adsorption gas chromatography/mass spectrometry. N(2)O levels in excess of the occupational exposure limit (OEL) value of 180mg/m(3) were registered in all ORs equipped with ventilation systems alone. The OEL value was exceeded several times in rooms with natural ventilation plus supplementary pressure ventilations and twice or less in those with pressure/exhaust ventilation systems or air conditioning. N(2)O levels below or within the OEL value were observed in rooms where the system of air conditioning or pressure/exhaust ventilation was combined with scavenging systems. Systems combining natural/pressure ventilation with scavenging were inadequate to maintain N(2)O concentration below the OEL value. Air conditioning and an efficient pressure

  15. B-Plant Canyon Ventilation Control System Description

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    MCDANIEL, K.S.

    1999-08-31

    Project W-059 installed a new B Plant Canyon Ventilation System. Monitoring and control of the system is implemented by the Canyon Ventilation Control System (CVCS). This document describes the CVCS system components which include a Programmable Logic Controller (PLC) coupled with an Operator Interface Unit (OIU) and application software. This document also includes an Alarm Index specifying the setpoints and technical basis for system analog and digital alarms.

  16. 46 CFR 153.310 - Ventilation system type.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Handling Space Ventilation § 153.310 Ventilation system type. A cargo handling space must have a permanent...

  17. 46 CFR 153.310 - Ventilation system type.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Handling Space Ventilation § 153.310 Ventilation system type. A cargo handling space must have a permanent...

  18. 46 CFR 153.310 - Ventilation system type.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Handling Space Ventilation § 153.310 Ventilation system type. A cargo handling space must have a permanent...

  19. 46 CFR 153.310 - Ventilation system type.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Handling Space Ventilation § 153.310 Ventilation system type. A cargo handling space must have a permanent...

  20. 46 CFR 153.310 - Ventilation system type.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Handling Space Ventilation § 153.310 Ventilation system type. A cargo handling space must have a permanent...

  1. Preoperational test report, recirculation ventilation systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Clifton, F.T.

    1997-11-11

    This represents a preoperational test report for Recirculation Ventilation Systems, Project W-030. Project W-030 provides a ventilation upgrade for the four Aging Waste Facility tanks. The system provides vapor space cooling of tanks AY1O1, AY102, AZ1O1, AZ102 and supports the ability to exhaust air from each tank. Each system consists of a valved piping loop, a fan, condenser, and moisture separator; equipment is located inside each respective tank farm in its own hardened building. The tests verify correct system operation and correct indications displayed by the central Monitor and Control System.

  2. Mathematical model for calculation of the heat-hydraulic modes of heating points of heat-supplying systems

    NASA Astrophysics Data System (ADS)

    Shalaginova, Z. I.

    2016-03-01

    The mathematical model and calculation method of the thermal-hydraulic modes of heat points, based on the theory of hydraulic circuits, being developed at the Melentiev Energy Systems Institute are presented. The redundant circuit of the heat point was developed, in which all possible connecting circuits (CC) of the heat engineering equipment and the places of possible installation of control valve were inserted. It allows simulating the operating modes both at central heat points (CHP) and individual heat points (IHP). The configuration of the desired circuit is carried out automatically by removing the unnecessary links. The following circuits connecting the heating systems (HS) are considered: the dependent circuit (direct and through mixing elevator) and independent one (through the heater). The following connecting circuits of the load of hot water supply (HWS) were considered: open CC (direct water pumping from pipelines of heat networks) and a closed CC with connecting the HWS heaters on single-level (serial and parallel) and two-level (sequential and combined) circuits. The following connecting circuits of the ventilation systems (VS) were also considered: dependent circuit and independent one through a common heat exchanger with HS load. In the heat points, water temperature regulators for the hot water supply and ventilation and flow regulators for the heating system, as well as to the inlet as a whole, are possible. According to the accepted decomposition, the model of the heat point is an integral part of the overall heat-hydraulic model of the heat-supplying system having intermediate control stages (CHP and IHP), which allows to consider the operating modes of the heat networks of different levels connected with each other through CHP as well as connected through IHP of consumers with various connecting circuits of local systems of heat consumption: heating, ventilation and hot water supply. The model is implemented in the Angara data

  3. 78 FR 51749 - Proposed Information Collection; Ventilation Plan and Main Fan Maintenance Record (Pertains to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-21

    ... maintaining a safe and healthful working environment. A well planned mine ventilation system is necessary to assure a fresh air supply to miners at all working places, to control the amounts of harmful airborne... usually present harsh and hostile working environments. The ventilation system is the most vital life...

  4. Verification of Energy Reduction Effect through Control Optimization of Supply Air Temperature in VRF-OAP System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, Je; Yoon, Hyun; Im, Piljae

    This paper developed an algorithm that controls the supply air temperature in the variable refrigerant flow (VRF), outdoor air processing unit (OAP) system, according to indoor and outdoor temperature and humidity, and verified the effects after applying the algorithm to real buildings. The VRF-OAP system refers to a heating, ventilation, and air conditioning (HVAC) system to complement a ventilation function, which is not provided in the VRF system. It is a system that supplies air indoors by heat treatment of outdoor air through the OAP, as a number of indoor units and OAPs are connected to the outdoor unit inmore » the VRF system simultaneously. This paper conducted experiments with regard to changes in efficiency and the cooling capabilities of each unit and system according to supply air temperature in the OAP using a multicalorimeter. Based on these results, an algorithm that controlled the temperature of the supply air in the OAP was developed considering indoor and outdoor temperatures and humidity. The algorithm was applied in the test building to verify the effects of energy reduction and the effects on indoor temperature and humidity. Loads were then changed by adjusting the number of conditioned rooms to verify the effect of the algorithm according to various load conditions. In the field test results, the energy reduction effect was approximately 15–17% at a 100% load, and 4–20% at a 75% load. However, no significant effects were shown at a 50% load. The indoor temperature and humidity reached a comfortable level.« less

  5. Verification of Energy Reduction Effect through Control Optimization of Supply Air Temperature in VRF-OAP System

    DOE PAGES

    Lee, Je; Yoon, Hyun; Im, Piljae; ...

    2017-12-27

    This paper developed an algorithm that controls the supply air temperature in the variable refrigerant flow (VRF), outdoor air processing unit (OAP) system, according to indoor and outdoor temperature and humidity, and verified the effects after applying the algorithm to real buildings. The VRF-OAP system refers to a heating, ventilation, and air conditioning (HVAC) system to complement a ventilation function, which is not provided in the VRF system. It is a system that supplies air indoors by heat treatment of outdoor air through the OAP, as a number of indoor units and OAPs are connected to the outdoor unit inmore » the VRF system simultaneously. This paper conducted experiments with regard to changes in efficiency and the cooling capabilities of each unit and system according to supply air temperature in the OAP using a multicalorimeter. Based on these results, an algorithm that controlled the temperature of the supply air in the OAP was developed considering indoor and outdoor temperatures and humidity. The algorithm was applied in the test building to verify the effects of energy reduction and the effects on indoor temperature and humidity. Loads were then changed by adjusting the number of conditioned rooms to verify the effect of the algorithm according to various load conditions. In the field test results, the energy reduction effect was approximately 15–17% at a 100% load, and 4–20% at a 75% load. However, no significant effects were shown at a 50% load. The indoor temperature and humidity reached a comfortable level.« less

  6. Characterization of natural ventilation in wastewater collection systems.

    PubMed

    Ward, Matthew; Corsi, Richard; Morton, Robert; Knapp, Tom; Apgar, Dirk; Quigley, Chris; Easter, Chris; Witherspoon, Jay; Pramanik, Amit; Parker, Wayne

    2011-03-01

    The purpose of the study was to characterize natural ventilation in full-scale gravity collection system components while measuring other parameters related to ventilation. Experiments were completed at four different locations in the wastewater collection systems of Los Angeles County Sanitation Districts, Los Angeles, California, and the King County Wastewater Treatment District, Seattle, Washington. The subject components were concrete gravity pipes ranging in diameter from 0.8 to 2.4 m (33 to 96 in.). Air velocity was measured in each pipe using a carbon-monoxide pulse tracer method. Air velocity was measured entering or exiting the components at vents using a standpipe and hotwire anemometer arrangement. Ambient wind speed, temperature, and relative humidity; headspace temperature and relative humidity; and wastewater flow and temperature were measured. The field experiments resulted in a large database of measured ventilation and related parameters characterizing ventilation in full-scale gravity sewers. Measured ventilation rates ranged from 23 to 840 L/s. The experimental data was used to evaluate existing ventilation models. Three models that were based upon empirical extrapolation, computational fluid dynamics, and thermodynamics, respectively, were evaluated based on predictive accuracy compared to the measured data. Strengths and weaknesses in each model were found and these observations were used to propose a concept for an improved ventilation model.

  7. Innovative ventilation system for animal anatomy laboratory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lacey, D.R.; Smith, D.C.

    1997-04-01

    A unique ventilation system was designed and built to reduce formaldehyde fumes in the large animal anatomy lab at the Vet Medical Center at Cornell University. The laboratory includes four rooms totaling 5,500 ft{sup 2}. The main room has 2,300 ft{sup 2} and houses the laboratory where up to 60 students dissect as many as 12 horses at a time. Other rooms are a cold storage locker, an animal preparation room and a smaller lab for specialized instruction. The large animal anatomy laboratory has a history of air quality complaints despite a fairly high ventilation rate of over 10 airmore » changes/hour. The horses are embalmed, creating a voluminous source of formaldehyde and phenol vapors. Budget constraints and increasingly stringent exposure limits for formaldehyde presented a great challenge to design a ventilation system that yields acceptable air quality. The design solution included two innovative elements: air-to-air heat recovery, and focused ventilation.« less

  8. [Implementation of modern trends in the methods of the ventilation support in the new apparatus for artificial lung ventilation Avenir-221 P].

    PubMed

    Gal'perin, Iu Sh; Alkhimova, L R; Dmitriev, N D; Kozlova, I A; Nemirovskiĭ, S B; Makarov, M V; Safronov, A Iu

    2005-01-01

    In the new ventilator Avenir-221 P modern lines of development of ventilation support in intensive therapy of adults and children are implemented. The capacities of the ventilator are successfully combined with its technical decisions which include microprocessor parametrical controlling, programming-controlled electric drive, an information saturation, intuitively clear control system, protection against interruption of power supply sources and oxygen feeding falls. A set of functional characteristics (modes VCV, PCV, Ass/Contr, PSV, SIMV, PEEP, Sigh, etc.) in combination with an original design make the device the most accessible and promising for application in intensive care and resuscitation units of a wide network of Russian hospitals and clinics. The ventilator Avenir-221 P has passed all required tests and is presently commercially available.

  9. Analysis of radon reduction and ventilation systems in uranium mines in China.

    PubMed

    Hu, Peng-hua; Li, Xian-jie

    2012-09-01

    Mine ventilation is the most important way of reducing radon in uranium mines. At present, the radon and radon progeny levels in Chinese uranium mines where the cut and fill stoping method is used are 3-5 times higher than those in foreign uranium mines, as there is not much difference in the investments for ventilation protection between Chinese uranium mines and international advanced uranium mines with compaction methodology. In this paper, through the analysis of radon reduction and ventilation systems in Chinese uranium mines and the comparison of advantages and disadvantages between a variety of ventilation systems in terms of radon control, the authors try to illustrate the reasons for the higher radon and radon progeny levels in Chinese uranium mines and put forward some problems in three areas, namely the theory of radon control and ventilation systems, radon reduction ventilation measures and ventilation management. For these problems, this paper puts forward some proposals regarding some aspects, such as strengthening scrutiny, verifying and monitoring the practical situation, making clear ventilation plans, strictly following the mining sequence, promoting training of ventilation staff, enhancing ventilation system management, developing radon reduction ventilation technology, purchasing ventilation equipment as soon as possible in the future, and so on.

  10. Control of airborne infectious diseases in ventilated spaces

    PubMed Central

    Nielsen, Peter V.

    2009-01-01

    We protect ourselves from airborne cross-infection in the indoor environment by supplying fresh air to a room by natural or mechanical ventilation. The air is distributed in the room according to different principles: mixing ventilation, displacement ventilation, etc. A large amount of air is supplied to the room to ensure a dilution of airborne infection. Analyses of the flow in the room show that there are a number of parameters that play an important role in minimizing airborne cross-infection. The air flow rate to the room must be high, and the air distribution pattern can be designed to have high ventilation effectiveness. Furthermore, personalized ventilation may reduce the risk of cross-infection, and in some cases, it can also reduce the source of infection. Personalized ventilation can especially be used in hospital wards, aircraft cabins and, in general, where people are in fixed positions. PMID:19740921

  11. The effect of helium on ventilator performance: study of five ventilators and a bedside Pitot tube spirometer.

    PubMed

    Oppenheim-Eden, A; Cohen, Y; Weissman, C; Pizov, R

    2001-08-01

    To assess in vitro the performance of five mechanical ventilators-Siemens 300 and 900C (Siemens-Elma; Solna, Sweden), Puritan Bennett 7200 (Nellcor Puritan Bennett; Pleasanton, CA), Evita 4 (Dragerwerk; Lubeck, Germany), and Bear 1000 (Bear Medical Systems; Riverside CA)-and a bedside sidestream spirometer (Datex CS3 Respiratory Module; Datex-Ohmeda; Helsinki, Finland) during ventilation with helium-oxygen mixtures. In vitro study. ICUs of two university-affiliated hospitals. Each ventilator was connected to 100% helium through compressed air inlets and then tested at three to six different tidal volume (VT) settings using various helium-oxygen concentrations (fraction of inspired oxygen [FIO(2)] of 0.2 to 1.0). FIO(2) and VT were measured with the Datex CS3 spirometer, and VT was validated with a water-displacement spirometer. The Puritan Bennett 7200 ventilator did not function with helium. With the other four ventilators, delivered FIO(2) was lower than the set FIO(2). For the Siemens 300 and 900C ventilators, this difference could be explained by the lack of 21% oxygen when helium was connected to the air supply port, while for the other two ventilators, a nonlinear relation was found. The VT of the Siemens 300 ventilator was independent of helium concentration, while for the other three ventilators, delivered VT was greater than the set VT and was dependent on helium concentration. During ventilation with 80% helium and 20% oxygen, VT increased to 125% of set VT for the Siemens 900C ventilator, and more than doubled for the Evita 4 and Bear 1000 ventilators. Under the same conditions, the Datex CS3 spirometer underestimated the delivered VT by about 33%. At present, no mechanical ventilator is calibrated for use with helium. This investigation offers correction factors for four ventilators for ventilation with helium.

  12. Impact of Room Ventilation Rates on Mouse Cage Ventilation and Microenvironment.

    PubMed

    Reeb, Carolyn K.; Jones, Robert B.; Bearg, David W.; Bedigian, Hendrick; Paigen, Beverly

    1997-01-01

    To assess the impact of room ventilation on animal cage microenvironment, intracage ventilation rate, temperature, humidity, and concentrations of carbon dioxide and ammonia were monitored in nonpressurized, bonnet-topped mouse cages. Cages on the top, middle, and bottom rows of a mouse rack were monitored at room ventilation rates of 0, 5, 10, and 20 air changes/h (ACH). Ventilation inside the animal cage increased somewhat from 12.8 to 18.9 ACH as room ventilation rate in- creased from 0 to 20 ACH, but the differences were not statistically significant, and most of the increase occurred in cages in the top row nearest to the fresh air supply. Cages containing mice had ventilation rate between 10 and 15 ACH even when room ventilation was reduced to 0 ACH; this ventilation is a result of the thermal heat load of the mice. After 6 days of soiled bedding, intracage ammonia concentration was c 3 ppm at all room ventilation rates and was not affected by increasing room ventilation. Temperature inside cages did not change with increasing ventilation. Humidity inside cages significantly decreased with increasing ventilation, from 55% relative humidity at 5 ACH to 36% relative humidity at 20 ACH. Carbon dioxide concentration decreased from 2,500 ppm to 1,900 ppm when ventilation rate increased from 5 ACH to 10 ACH, but no further significant decrease was observed at 20 ACH. In conclusion, increasing the room ventilation rate higher than 5 ACH did not result in significant improvements in the cage microenvironment.

  13. Pressure Dynamic Characteristics of Pressure Controlled Ventilation System of a Lung Simulator

    PubMed Central

    Shi, Yan; Ren, Shuai; Cai, Maolin; Xu, Weiqing; Deng, Qiyou

    2014-01-01

    Mechanical ventilation is an important life support treatment of critically ill patients, and air pressure dynamics of human lung affect ventilation treatment effects. In this paper, in order to obtain the influences of seven key parameters of mechanical ventilation system on the pressure dynamics of human lung, firstly, mechanical ventilation system was considered as a pure pneumatic system, and then its mathematical model was set up. Furthermore, to verify the mathematical model, a prototype mechanical ventilation system of a lung simulator was proposed for experimental study. Last, simulation and experimental studies on the air flow dynamic of the mechanical ventilation system were done, and then the pressure dynamic characteristics of the mechanical system were obtained. The study can be referred to in the pulmonary diagnostics, treatment, and design of various medical devices or diagnostic systems. PMID:25197318

  14. Numerical simulation of volume-controlled mechanical ventilated respiratory system with 2 different lungs.

    PubMed

    Shi, Yan; Zhang, Bolun; Cai, Maolin; Zhang, Xiaohua Douglas

    2017-09-01

    Mechanical ventilation is a key therapy for patients who cannot breathe adequately by themselves, and dynamics of mechanical ventilation system is of great significance for life support of patients. Recently, models of mechanical ventilated respiratory system with 1 lung are used to simulate the respiratory system of patients. However, humans have 2 lungs. When the respiratory characteristics of 2 lungs are different, a single-lung model cannot reflect real respiratory system. In this paper, to illustrate dynamic characteristics of mechanical ventilated respiratory system with 2 different lungs, we propose a mathematical model of mechanical ventilated respiratory system with 2 different lungs and conduct experiments to verify the model. Furthermore, we study the dynamics of mechanical ventilated respiratory system with 2 different lungs. This research study can be used for improving the efficiency and safety of volume-controlled mechanical ventilation system. Copyright © 2016 John Wiley & Sons, Ltd.

  15. Operating and maintaining your heat recovery ventilator (HRV) -- Revised edition. Home heating and cooling series, Number 8

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    Heat recovery ventilators (HRVs) differ from other mechanical ventilation devices by their ability to exchange heat between supply and exhaust air streams, which reduces the cost of heating or cooling fresh air. This booklet discusses the need for mechanical ventilation in conventional and energy-efficient homes, an explains the components of a HRV system, how to operate and maintain the system, and how to solve operating problems. A maintenance chart and schedule and a HRV troubleshooting guide are included.

  16. Analysis of the systems of ventilation of residential houses of Ukraine and Estonia

    NASA Astrophysics Data System (ADS)

    Savchenko, Olena; Zhelykh, Vasyl; Voll, Hendrik

    2017-12-01

    The most common ventilation system in residential buildings in Ukraine is natural ventilation. In recent years, due to increased tightness of structures, an increase in the content of synthetic finishing materials in them, the quality of microclimate parameters deteriorated. One of the measures to improve the parameters of indoor air in residential buildings is the use of mechanical inflow and exhaust ventilation system. In this article the regulatory documents concerning the design of ventilation systems in Ukraine and Estonia and the requirements for air exchange in residential buildings are considered. It is established that the existing normative documents in Ukraine are analogous to European norms, which allow design the system of ventilation of residential buildings according to European standards. However, the basis for the design of ventilation systems in Ukraine is the national standards, in which mechanical ventilation, unfortunately, is provided only for the design of high-rise buildings. To maintain acceptable microclimate parameters in residential buildings, it is advisable for designers to apply the requirements for designing ventilation systems in accordance with European standards.

  17. 30 CFR 36.45 - Quantity of ventilating air.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Quantity of ventilating air. 36.45 Section 36... TRANSPORTATION EQUIPMENT Test Requirements § 36.45 Quantity of ventilating air. (a) Results of the engine tests shall be used to calculate ventilation (cubic feet of air per minute) that shall be supplied by positive...

  18. 30 CFR 36.45 - Quantity of ventilating air.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Quantity of ventilating air. 36.45 Section 36... TRANSPORTATION EQUIPMENT Test Requirements § 36.45 Quantity of ventilating air. (a) Results of the engine tests shall be used to calculate ventilation (cubic feet of air per minute) that shall be supplied by positive...

  19. 30 CFR 36.45 - Quantity of ventilating air.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Quantity of ventilating air. 36.45 Section 36... TRANSPORTATION EQUIPMENT Test Requirements § 36.45 Quantity of ventilating air. (a) Results of the engine tests shall be used to calculate ventilation (cubic feet of air per minute) that shall be supplied by positive...

  20. Anaesthesia ventilators.

    PubMed

    Jain, Rajnish K; Swaminathan, Srinivasan

    2013-09-01

    Anaesthesia ventilators are an integral part of all modern anaesthesia workstations. Automatic ventilators in the operating rooms, which were very simple with few modes of ventilation when introduced, have become very sophisticated with many advanced ventilation modes. Several systems of classification of anaesthesia ventilators exist based upon various parameters. Modern anaesthesia ventilators have either a double circuit, bellow design or a single circuit piston configuration. In the bellows ventilators, ascending bellows design is safer than descending bellows. Piston ventilators have the advantage of delivering accurate tidal volume. They work with electricity as their driving force and do not require a driving gas. To enable improved patient safety, several modifications were done in circle system with the different types of anaesthesia ventilators. Fresh gas decoupling is a modification done in piston ventilators and in descending bellows ventilator to reduce th incidence of ventilator induced volutrauma. In addition to the conventional volume control mode, modern anaesthesia ventilators also provide newer modes of ventilation such as synchronised intermittent mandatory ventilation, pressure-control ventilation and pressure-support ventilation (PSV). PSV mode is particularly useful for patients maintained on spontaneous respiration with laryngeal mask airway. Along with the innumerable benefits provided by these machines, there are various inherent hazards associated with the use of the ventilators in the operating room. To use these workstations safely, it is important for every Anaesthesiologist to have a basic understanding of the mechanics of these ventilators and breathing circuits.

  1. 46 CFR 194.10-25 - Ventilation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... and shall serve no other space. Weather cowls shall be provided with a double layer of wire screen of... temperature below 100 °F. with 88 °F. weather air. Mechanical cooling may be used where ventilation... 130 °F. with an assumed outside temperature of 115 °F. (2) Ventilation supply weather openings shall...

  2. 46 CFR 194.10-25 - Ventilation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... and shall serve no other space. Weather cowls shall be provided with a double layer of wire screen of... temperature below 100 °F. with 88 °F. weather air. Mechanical cooling may be used where ventilation... 130 °F. with an assumed outside temperature of 115 °F. (2) Ventilation supply weather openings shall...

  3. 46 CFR 194.10-25 - Ventilation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... and shall serve no other space. Weather cowls shall be provided with a double layer of wire screen of... temperature below 100 °F. with 88 °F. weather air. Mechanical cooling may be used where ventilation... 130 °F. with an assumed outside temperature of 115 °F. (2) Ventilation supply weather openings shall...

  4. 46 CFR 194.10-25 - Ventilation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... and shall serve no other space. Weather cowls shall be provided with a double layer of wire screen of... temperature below 100 °F. with 88 °F. weather air. Mechanical cooling may be used where ventilation... 130 °F. with an assumed outside temperature of 115 °F. (2) Ventilation supply weather openings shall...

  5. VWPS: A Ventilator Weaning Prediction System with Artificial Intelligence

    NASA Astrophysics Data System (ADS)

    Chen, Austin H.; Chen, Guan-Ting

    How to wean patients efficiently off mechanical ventilation continues to be a challenge for medical professionals. In this paper we have described a novel approach to the study of a ventilator weaning prediction system (VWPS). Firstly, we have developed and written three Artificial Neural Network (ANN) algorithms to predict a weaning successful rate based on the clinical data. Secondly, we have implemented two user-friendly weaning success rate prediction systems; the VWPS system and the BWAP system. Both systems could be used to help doctors objectively and effectively predict whether weaning is appropriate for patients based on the patients' clinical data. Our system utilizes the powerful processing abilities of MatLab. Thirdly, we have calculated the performance through measures such as sensitivity and accuracy for these three algorithms. The results show a very high sensitivity (around 80%) and accuracy (around 70%). To our knowledge, this is the first design approach of its kind to be used in the study of ventilator weaning success rate prediction.

  6. Evaluation of Mechanical Ventilator Use with Liquid Oxygen Systems

    DTIC Science & Technology

    2017-02-22

    patients using long-term liquid oxygen differ from those on traditional treatment with oxygen concentrators and/or compressed gas cylinders? A...AFRL-SA-WP-SR-2017-0006 Evaluation of Mechanical Ventilator Use with Liquid Oxygen Systems Thomas Blakeman, MSc, RRT; Dario...To) August 2014 – September 2016 4. TITLE AND SUBTITLE Evaluation of Mechanical Ventilator Use with Liquid Oxygen Systems 5a. CONTRACT NUMBER

  7. Hydrostatic Hyperbaric Chamber Ventilation System

    NASA Technical Reports Server (NTRS)

    Sargusingh, Miriam M.

    2011-01-01

    The hydrostatic hyperbaric chamber (HHC) represents the merger of several technologies in development for NASA aerospace applications, harnessed to directly benefit global health. NASA has significant experience developing composite hyperbaric chambers for a variety of applications, including the treatment of medical conditions. NASA also has researched the application of water-filled vessels to increase tolerance of acceleration forces. The combination of these two applications has resulted in the hydrostatic chamber, which has been conceived as a safe, affordable means of making hyperbaric oxygen therapy available in the developing world for the treatment of a variety of medical conditions. Specifically, hyperbaric oxygen therapy is highly-desired as a possibly curative treatment for Buruli Ulcer, an infectious condition that afflicts children in sub-Saharan Africa. Hyperbaric oxygen therapy is simply too expensive and too dangerous to implement in the developing world using standard equipment. The hydrostatic hyperbaric chamber technology changes the paradigm. The HHC differs from standard hyperbaric chambers in that the majority of its volume is filled with water which is pressurized by oxygen being supplied in the portion of the chamber containing the patient s head. This greatly reduces the amount of oxygen required to sustain a hyperbaric atmosphere, thereby making the system more safe and economical to operate. An effort was taken to develop an HHC system to apply HBOT to children that is simple and robust enough to support transport, assembly, maintenance and operation in developing countries. This paper details the concept for an HHC ventilation and pressurization system that will provide controlled pressurization of the system, and provide adequate washout of carbon dioxide while the subject is enclosed in the confined space during the administration of the medical treatment. The concept took into consideration operational complexity, safety to the

  8. Applied patent RFID systems for building reacting HEPA air ventilation system in hospital operation rooms.

    PubMed

    Lin, Jesun; Pai, Jar-Yuan; Chen, Chih-Cheng

    2012-12-01

    RFID technology, an automatic identification and data capture technology to provide identification, tracing, security and so on, was widely applied to healthcare industry in these years. Employing HEPA ventilation system in hospital is a way to ensure healthful indoor air quality to protect patients and healthcare workers against hospital-acquired infections. However, the system consumes lots of electricity which cost a lot. This study aims to apply the RFID technology to offer a unique medical staff and patient identification, and reacting HEPA air ventilation system in order to reduce the cost, save energy and prevent the prevalence of hospital-acquired infection. The system, reacting HEPA air ventilation system, contains RFID tags (for medical staffs and patients), sensor, and reacting system which receives the information regarding the number of medical staff and the status of the surgery, and controls the air volume of the HEPA air ventilation system accordingly. A pilot program was carried out in a unit of operation rooms of a medical center with 1,500 beds located in central Taiwan from Jan to Aug 2010. The results found the air ventilation system was able to function much more efficiently with less energy consumed. Furthermore, the indoor air quality could still keep qualified and hospital-acquired infection or other occupational diseases could be prevented.

  9. Proportional mechanical ventilation through PWM driven on/off solenoid valve.

    PubMed

    Sardellitti, I; Cecchini, S; Silvestri, S; Caldwell, D G

    2010-01-01

    Proportional strategies for artificial ventilation are the most recent form of synchronized partial ventilatory assistance and intra-breath control techniques available in clinical practice. Currently, the majority of commercial ventilators allowing proportional ventilation uses proportional valves to generate the flow rate pattern. This paper proposes on-off solenoid valves for proportional ventilation given their small size, low cost and short switching time, useful for supplying high frequency ventilation. A new system based on a novel fast switching driver circuit combined with on/off solenoid valve is developed. The average short response time typical of onoff solenoid valves was further reduced through the driving circuit for the implementation of PWM control. Experimental trials were conducted for identifying the dynamic response of the PWM driven on/off valve and for verifying its effectiveness in generating variable-shaped ventilatory flow rate patterns. The system was able to smoothly follow the reference flow rate patterns also changing in time intervals as short as 20 ms, achieving a flow rate resolution up to 1 L/min and repeatability in the order of 0.5 L/min. Preliminary results showed the feasibility of developing a stand alone portable device able to generate both proportional and high frequency ventilation by only using on-off solenoid valves.

  10. Field evaluation of ventilation system performance in enclosed parking garages

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ayari, A.M.; Grot, D.A.; Krarti, M.

    2000-07-01

    This paper summarizes the results of a field study to determine the ventilation requirements and the contaminant levels in existing enclosed parking garages. The testing was conducted in seven parking garages with different sizes, traffic flow patterns, vehicle types, and locations. In particular, the study compares the actual ventilation rates measured using the tracer gas technique with the ventilation requirements of ANSI/ASHRAE Standard 62-1989. In addition, the field test evaluated the effectiveness of the existing ventilation systems in maintaining acceptable contaminant levels within enclosed parking garages.

  11. Optimization of Ventilation Energy Demands and Indoor Air Quality in High-Performance Homes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hun, Diana E; Jackson, Mark C; Shrestha, Som S

    2014-01-01

    High-performance homes require that ventilation energy demands and indoor air quality (IAQ) be simultaneously optimized. We attempted to bridge these two areas by conducting tests in a research house located in Oak Ridge, TN, that was 20 months old, energy-efficient (i.e., expected to consume 50% less energy than a house built per the 2006 IRC), tightly-built (i.e., natural ventilation rate ~0.02 h-1), unoccupied, and unfurnished. We identified air pollutants of concern in the test home that could generally serve as indicators of IAQ, and conduced field experiments and computer simulations to determine the effectiveness and energy required by various techniquesmore » that lessened the concentration of these contaminants. Formaldehyde was selected as the main pollutant of concern among the contaminants that were sampled in the initial survey because it was the only compound that showed concentrations that were greater than the recommended exposure levels. Field data indicate that concentrations were higher during the summer primarily because emissions from sources rise with increases in temperature. Furthermore, supply ventilation and gas-phase filtration were effective means to reduce formaldehyde concentrations; however, exhaust ventilation had minimal influence on this pollutant. Results from simulations suggest that formaldehyde concentrations obtained while ventilating per ASHRAE 62.2-2010 could be decreased by about 20% from May through September through three strategies: 1) increasing ASHRAE supply ventilation by a factor of two, 2) reducing the thermostat setpoint from 76 to 74 F, or 3) running a gas-phase filtration system while decreasing supply ventilation per ASHRAE by half. In the mixed-humid climate of Oak Ridge, these strategies caused increases in electricity cost of ~$5 to ~$15/month depending on outdoor conditions.« less

  12. Water spray ventilator system for continuous mining machines

    DOEpatents

    Page, Steven J.; Mal, Thomas

    1995-01-01

    The invention relates to a water spray ventilator system mounted on a continuous mining machine to streamline airflow and provide effective face ventilation of both respirable dust and methane in underground coal mines. This system has two side spray nozzles mounted one on each side of the mining machine and six spray nozzles disposed on a manifold mounted to the underside of the machine boom. The six spray nozzles are angularly and laterally oriented on the manifold so as to provide non-overlapping spray patterns along the length of the cutter drum.

  13. The correlation of Acanthamoeba from the ventilation system with other environmental parameters in commercial buildings as possible indicator for indoor air quality.

    PubMed

    Ooi, Soo Shen; Mak, Joon Wah; Chen, Donald K F; Ambu, Stephen

    2017-02-07

    The free-living protozoan Acanthamoeba is an opportunistic pathogen that is ubiquitous in our environment. However, its role in affecting indoor air quality and ill-health of indoor occupants is relatively unknown. The present study investigated the presence of Acanthamoeba from the ventilation system and its correlation with other indoor air quality parameters, used in the industry code of practice and its potential as an indicator for indoor air quality. Indoor air quality assessments were carried out in nine commercial buildings with approval from the building management, and the parameters assessed were as recommended by the Department of Occupational Safety and Health. The presence of Acanthamoeba was determined through dust swabs from the ventilation system and indoor furniture. Logistic regression was performed to study the correlation between assessed parameters and occupants' complaints. A total of 107 sampling points were assessed and 40.2% of the supplying air diffuser and blowing fan and 15% of the furniture were positive for cysts. There was a significant correlation between Acanthamoeba detected from the ventilation system with ambient total fungus count (r=0.327; p=0.01) and respirable particulates (r=0.276; p=0.01). Occupants' sick building syndrome experience also correlated with the presence of Acanthamoeba in the ventilation system (r=0.361; p=0.01) and those detected on the furniture (r=0.290; p=0.01). Logistic regression showed that there was a five-fold probability of sick building syndrome among occupants when Acanthamoeba was detected in the ventilation system.

  14. The correlation of Acanthamoeba from the ventilation system with other environmental parameters in commercial buildings as possible indicator for indoor air quality

    PubMed Central

    OOI, Soo Shen; MAK, Joon Wah; CHEN, Donald K.F.; AMBU, Stephen

    2016-01-01

    The free-living protozoan Acanthamoeba is an opportunistic pathogen that is ubiquitous in our environment. However, its role in affecting indoor air quality and ill-health of indoor occupants is relatively unknown. The present study investigated the presence of Acanthamoeba from the ventilation system and its correlation with other indoor air quality parameters, used in the industry code of practice and its potential as an indicator for indoor air quality. Indoor air quality assessments were carried out in nine commercial buildings with approval from the building management, and the parameters assessed were as recommended by the Department of Occupational Safety and Health. The presence of Acanthamoeba was determined through dust swabs from the ventilation system and indoor furniture. Logistic regression was performed to study the correlation between assessed parameters and occupants’ complaints. A total of 107 sampling points were assessed and 40.2% of the supplying air diffuser and blowing fan and 15% of the furniture were positive for cysts. There was a significant correlation between Acanthamoeba detected from the ventilation system with ambient total fungus count (r=0.327; p=0.01) and respirable particulates (r=0.276; p=0.01). Occupants’ sick building syndrome experience also correlated with the presence of Acanthamoeba in the ventilation system (r=0.361; p=0.01) and those detected on the furniture (r=0.290; p=0.01). Logistic regression showed that there was a five-fold probability of sick building syndrome among occupants when Acanthamoeba was detected in the ventilation system. PMID:27476379

  15. Hydrostatic Hyperbaric Chamber Ventilation System

    NASA Technical Reports Server (NTRS)

    Sarguisingh, Miriam J.

    2012-01-01

    The hydrostatic hyperbaric chamber (HHC) represents the merger of several technologies in development for NASA aerospace applications, harnessed to directly benefit global health. NASA has significant experience developing composite hyperbaric chambers for a variety of applications. NASA also has researched the application of water-filled vessels to increase tolerance of acceleration forces. The combination of these two applications has resulted in the hydrostatic chamber, which has been conceived as a safe, affordable means of making hyperbaric oxygen therapy (HBOT) available in the developing world for the treatment of a variety of medical conditions. Specifically, HBOT is highly-desired as a possibly curative treatment for Buruli Ulcer, an infectious condition that afflicts children in sub-Saharan Africa. HBOT is simply too expensive and too dangerous to implement in the developing world using standard equipment. The HHC technology changes the paradigm. The HHC differs from standard hyperbaric chambers in that the majority of its volume is filled with water which is pressurized by oxygen being supplied in the portion of the chamber containing the patient s head. This greatly reduces the amount of oxygen required to sustain a hyperbaric atmosphere, thereby making the system more safe and economical to operate. An effort was taken to develop an HHC system to apply HBOT to children that is simple and robust enough to support transport, assembly, maintenance and operation in developing countries. This paper details the concept for an HHC ventilation and pressurization system to provide controlled pressurization and adequate washout of carbon dioxide while the subject is enclosed in the confined space during the administration of the medical treatment. The concept took into consideration operational complexity, safety to the patient and operating personnel, and physiological considerations. The simple schematic, comprised of easily acquired commercial hardware

  16. Software Configuration Management Plan for the B-Plant Canyon Ventilation Control System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    MCDANIEL, K.S.

    1999-08-31

    Project W-059 installed a new B Plant Canyon Ventilation System. Monitoring and control of the system is implemented by the Canyon Ventilation Control System (CVCS). This Software Configuration Management Plan provides instructions for change control of the CVCS.

  17. A perfluorochemical loss/restoration (L/R) system for tidal liquid ventilation.

    PubMed

    Libros, R; Philips, C M; Wolfson, M R; Shaffer, T H

    2000-01-01

    Tidal liquid ventilation is the transport of dissolved respiratory gases via volume exchange of perfluorochemical (PFC) liquid to and from the PFC-filled lung. All gas-liquid surface tension is eliminated, increasing compliance and providing lung protection due to lower inflation pressures. Tidal liquid ventilation is achieved by cycling fluid from a reservoir to and from the lung by a ventilator. Current approaches are microprocessor-based with feedback control. During inspiration, warmed oxygenated PFC liquid is pumped from a fluid reservoir/gas exchanger into the lung. PFC fluid is conserved by condensing (60-80% efficiency) vapor in the expired gas. A feedback-control system was developed to automatically replace PFC lost due to condenser inefficiency. This loss/restoration (L/R) system consists of a PFC-vapor thermal detector (+/- 2.5%), pneumatics, amplifiers, a gas flow detector (+/- 1%), a PFC pump (+/- 5%), and a controller. Gravimetric studies of perflubron loss from a flask due to evaporation were compared with experimental L/R results and found to be within +/- 1.4%. In addition, when L/R studies were conducted with a previously reported liquid ventilation system over a four-hour period, the L/R system maintained system perflubron volume to within +/- 1% of prime volume and 11.5% of replacement volume, and the difference between experimental PFC loss and that of the L/R system was 1.8 mL/hr. These studies suggest that the PFC L/R system may have significant economic (appropriate dosing for PFC loss) as well as physiologic (maintenance of PFC inventory in the lungs and liquid ventilator) impact on liquid ventilation procedures.

  18. Energy Use Consequences of Ventilating a Net-Zero Energy House

    PubMed Central

    Ng, Lisa C.; Payne, W. Vance

    2016-01-01

    A Net-Zero Energy Residential Test Facility (NZERTF) has been constructed at the National Institute of Standards and Technology (NIST) in Gaithersburg, Maryland to demonstrate that a home similar in size, aesthetics, and amenities to those in the surrounding communities can achieve net-zero energy use over the course of a year while meeting the average electricity and water use needs of a family of four in the United States. The facility incorporates renewable energy and energy efficient technologies, including an air-to-air heat pump system, a solar photovoltaic system, a solar thermal domestic hot water system, and a heat recovery ventilation system sized to meet American Society of Heating, Refrigeration, and Air-Conditioning Engineers (ASHRAE) Standard 62.2-2010 ventilation requirements. The largest energy end use within the home was space conditioning, which included heat loss through the building envelope, ventilation air supplied by the heat recovery ventilator (HRV), and internal loads. While HRVs are often described as being able to save energy when compared to ventilating without heat recovery, there have been no studies using a full year of measured data that determine the thermal load and energy impacts of HRV-based ventilation on the central heating and cooling system. Over the course of a year, continuous operation of the HRV at the NZERTF resulted in an annual savings of 7 % in heat pump energy use compared with the hypothetical case of ventilating without heat recovery. The heat pump electrical use varied from an increase of 5 % in the cooling months to 36 % savings in the heating months compared with ventilation without heat recovery. The increase in the cooling months occurred when the outdoor temperature was lower than the indoor temperature, during which the availability of an economizer mode would have been beneficial. Nevertheless, the fan energy required to operate the selected HRV at the NZERTF paid for itself in the heat pump energy saved

  19. Energy Use Consequences of Ventilating a Net-Zero Energy House.

    PubMed

    Ng, Lisa C; Payne, W Vance

    2016-03-05

    A Net-Zero Energy Residential Test Facility (NZERTF) has been constructed at the National Institute of Standards and Technology (NIST) in Gaithersburg, Maryland to demonstrate that a home similar in size, aesthetics, and amenities to those in the surrounding communities can achieve net-zero energy use over the course of a year while meeting the average electricity and water use needs of a family of four in the United States. The facility incorporates renewable energy and energy efficient technologies, including an air-to-air heat pump system, a solar photovoltaic system, a solar thermal domestic hot water system, and a heat recovery ventilation system sized to meet American Society of Heating, Refrigeration, and Air-Conditioning Engineers (ASHRAE) Standard 62.2-2010 ventilation requirements. The largest energy end use within the home was space conditioning, which included heat loss through the building envelope, ventilation air supplied by the heat recovery ventilator (HRV), and internal loads. While HRVs are often described as being able to save energy when compared to ventilating without heat recovery, there have been no studies using a full year of measured data that determine the thermal load and energy impacts of HRV-based ventilation on the central heating and cooling system. Over the course of a year, continuous operation of the HRV at the NZERTF resulted in an annual savings of 7 % in heat pump energy use compared with the hypothetical case of ventilating without heat recovery. The heat pump electrical use varied from an increase of 5 % in the cooling months to 36 % savings in the heating months compared with ventilation without heat recovery. The increase in the cooling months occurred when the outdoor temperature was lower than the indoor temperature, during which the availability of an economizer mode would have been beneficial. Nevertheless, the fan energy required to operate the selected HRV at the NZERTF paid for itself in the heat pump energy saved

  20. A dual closed-loop control system for mechanical ventilation.

    PubMed

    Tehrani, Fleur; Rogers, Mark; Lo, Takkin; Malinowski, Thomas; Afuwape, Samuel; Lum, Michael; Grundl, Brett; Terry, Michael

    2004-04-01

    Closed-loop mechanical ventilation has the potential to provide more effective ventilatory support to patients with less complexity than conventional ventilation. The purpose of this study was to investigate the effectiveness of an automatic technique for mechanical ventilation. Two closed-loop control systems for mechanical ventilation are combined in this study. In one of the control systems several physiological data are used to automatically adjust the frequency and tidal volume of breaths of a patient. This method, which is patented under US Patent number 4986268, uses the criterion of minimal respiratory work rate to provide the patient with a natural pattern of breathing. The inputs to the system include data representing CO2 and O2 levels of the patient as well as respiratory compliance and airway resistance. The I:E ratio is adjusted on the basis of the respiratory time constant to allow for effective emptying of the lungs in expiration and to avoid intrinsic positive end expiratory pressure (PEEP). This system is combined with another closed-loop control system for automatic adjustment of the inspired fraction of oxygen of the patient. This controller uses the feedback of arterial oxygen saturation of the patient and combines a rapid stepwise control procedure with a proportional-integral-derivative (PID) control algorithm to automatically adjust the oxygen concentration in the patient's inspired gas. The dual closed-loop control system has been examined by using mechanical lung studies, computer simulations and animal experiments. In the mechanical lung studies, the ventilation controller adjusted the breathing frequency and tidal volume in a clinically appropriate manner in response to changes in respiratory mechanics. The results of computer simulations and animal studies under induced disturbances showed that blood gases were returned to the normal physiologic range in less than 25 s by the control system. In the animal experiments understeady

  1. Effects of types of ventilation system on indoor particle concentrations in residential buildings.

    PubMed

    Park, J S; Jee, N-Y; Jeong, J-W

    2014-12-01

    The objective of this study was to quantify the influence of ventilation systems on indoor particle concentrations in residential buildings. Fifteen occupied, single-family apartments were selected from three sites. The three sites have three different ventilation systems: unbalanced mechanical ventilation, balanced mechanical ventilation, and natural ventilation. Field measurements were conducted between April and June 2012, when outdoor air temperatures were comfortable. Number concentrations of particles, PM2.5 and CO2 , were continuously measured both outdoors and indoors. In the apartments with natural ventilation, I/O ratios of particle number concentrations ranged from 0.56 to 0.72 for submicron particles, and from 0.25 to 0.60 for particles larger than 1.0 μm. The daily average indoor particle concentration decreased to 50% below the outdoor level for submicron particles and 25% below the outdoor level for fine particles, when the apartments were mechanically ventilated. The two mechanical ventilation systems reduced the I/O ratios by 26% for submicron particles and 65% for fine particles compared with the natural ventilation. These results showed that mechanical ventilation can reduce exposure to outdoor particles in residential buildings. Results of this study confirm that mechanical ventilation with filtration can significantly reduce indoor particle levels compared with natural ventilation. The I/O ratios of particles substantially varied at the naturally ventilated apartments because of the influence of variable window opening conditions and unsteadiness of wind flow on the penetration of outdoor air particles. For better prediction of the exposure to outdoor particles in naturally ventilated residential buildings, it is important to understand the penetration of outdoor particles with variable window opening conditions. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  2. Talaromyces rubrifaciens, a new species discovered from heating, ventilation and air conditioning systems in China.

    PubMed

    Luo, Yi; Lu, Xiaohong; Bi, Wu; Liu, Fan; Gao, Weiwei

    2016-01-01

    A new Talaromyces species, T. rubrifaciens, was isolated from supply air outlets of heating, ventilation and air conditioning (HVAC) systems in three kinds of public building in Beijing and Nanjing, China. Morphologically it exhibits many characters of section Trachyspermi but is distinguished from other species of this section by restricted growth and broad and strictly biverticillate conidiophores. Phylogenetic analyses based on the internal transcribed spacer rDNA (ITS), β-tubulin (BenA), calmodulin (CaM) and RNA polymerase second largest subunit (RPB2) genes reveal that T. rubrifaciens is a distinct species in section Trachyspermi. © 2016 by The Mycological Society of America.

  3. Investigation of induced recirculation during planned ventilation system maintenance

    PubMed Central

    Pritchard, C.J.; Scott, D.F.; Noll, J.D.; Voss, B.; Leonis, D.

    2015-01-01

    The Office of Mine Safety and Health Research (OMSHR) investigated ways to increase mine airflow to underground metal/nonmetal (M/NM) mine working areas to improve miners’ health and safety. One of those areas is controlled recirculation. Because the quantity of mine air often cannot be increased, reusing part of the ventilating air can be an effective alternative, if implemented properly, until the capacity of the present system is improved. The additional airflow can be used to provide effective dilution of contaminants and higher flow velocities in the underground mine environment. Most applications of controlled recirculation involve taking a portion of the return air and passing it back into the intake to increase the air volume delivered to the desired work areas. OMSHR investigated a Nevada gold mine where shaft rehabilitation was in progress and one of the two main fans was shut down to allow reduced air velocity for safe shaft work. Underground booster fan operating pressures were kept constant to maintain airflow to work areas, inducing controlled recirculation in one work zone. Investigation into system behavior and the effects of recirculation on the working area during times of reduced primary ventilation system airflow would provide additional information on implementation of controlled recirculation into the system and how these events affect M/NM ventilation systems. The National Institute for Occupational Safety and Health monitored the ventilation district when both main fans were operating and another scenario with one of the units turned off for maintenance. Airflow and contaminants were measured to determine the exposure effects of induced recirculation on miner health. Surveys showed that 19% controlled recirculation created no change in the overall district airflow distribution and a small reduction in district fresh air intake. Total dust levels increased only modestly and respirable dust levels were also low. Diesel particulate matter

  4. Procedures and Standards for Residential Ventilation System Commissioning: An Annotated Bibliography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stratton, J. Chris; Wray, Craig P.

    2013-04-01

    Beginning with the 2008 version of Title 24, new homes in California must comply with ANSI/ASHRAE Standard 62.2-2007 requirements for residential ventilation. Where installed, the limited data available indicate that mechanical ventilation systems do not always perform optimally or even as many codes and forecasts predict. Commissioning such systems when they are installed or during subsequent building retrofits is a step towards eliminating deficiencies and optimizing the tradeoff between energy use and acceptable IAQ. Work funded by the California Energy Commission about a decade ago at Berkeley Lab documented procedures for residential commissioning, but did not focus on ventilation systems.more » Since then, standards and approaches for commissioning ventilation systems have been an active area of work in Europe. This report describes our efforts to collect new literature on commissioning procedures and to identify information that can be used to support the future development of residential-ventilation-specific procedures and standards. We recommend that a standardized commissioning process and a commissioning guide for practitioners be developed, along with a combined energy and IAQ benefit assessment standard and tool, and a diagnostic guide for estimating continuous pollutant emission rates of concern in residences (including a database that lists emission test data for commercially-available labeled products).« less

  5. 33 CFR 183.630 - Standards for natural ventilation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... boat achieved by having: (1) A supply opening or duct from the atmosphere or from a ventilated compartment or from a compartment that is open to the atmosphere; and (2) An exhaust opening into another ventilated compartment or an exhaust duct to the atmosphere. (b) Each exhaust opening or exhaust duct must...

  6. 33 CFR 183.630 - Standards for natural ventilation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... boat achieved by having: (1) A supply opening or duct from the atmosphere or from a ventilated compartment or from a compartment that is open to the atmosphere; and (2) An exhaust opening into another ventilated compartment or an exhaust duct to the atmosphere. (b) Each exhaust opening or exhaust duct must...

  7. 33 CFR 183.630 - Standards for natural ventilation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... boat achieved by having: (1) A supply opening or duct from the atmosphere or from a ventilated compartment or from a compartment that is open to the atmosphere; and (2) An exhaust opening into another ventilated compartment or an exhaust duct to the atmosphere. (b) Each exhaust opening or exhaust duct must...

  8. 46 CFR 168.15-50 - Ventilation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the purpose of the space and route of the vessel. (b) When mechanical ventilation is provided for sleeping rooms, washrooms, toilet rooms, hospital spaces, and messrooms, these spaces must be supplied with...

  9. 46 CFR 168.15-50 - Ventilation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... the purpose of the space and route of the vessel. (b) When mechanical ventilation is provided for sleeping rooms, washrooms, toilet rooms, hospital spaces, and messrooms, these spaces must be supplied with...

  10. 46 CFR 168.15-50 - Ventilation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... the purpose of the space and route of the vessel. (b) When mechanical ventilation is provided for sleeping rooms, washrooms, toilet rooms, hospital spaces, and messrooms, these spaces must be supplied with...

  11. 46 CFR 168.15-50 - Ventilation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... the purpose of the space and route of the vessel. (b) When mechanical ventilation is provided for sleeping rooms, washrooms, toilet rooms, hospital spaces, and messrooms, these spaces must be supplied with...

  12. 46 CFR 168.15-50 - Ventilation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the purpose of the space and route of the vessel. (b) When mechanical ventilation is provided for sleeping rooms, washrooms, toilet rooms, hospital spaces, and messrooms, these spaces must be supplied with...

  13. Reproductive Performance of Mice in Disposable and Standard Individually Ventilated Cages

    PubMed Central

    Ferguson, Danielle R; Bailey, Michele M

    2013-01-01

    This study assessed the reproductive performance of mice housed in 2 types of individually ventilated caging systems. Breeding pairs from 48 female and 24 male mice of 3 established transgenic mouse breeding colonies were placed in either a standard or disposable ventilated caging system. For 3 breeding cycles, the number of pups born, pup survival rate to weaning, time interval between litters, and pup weights were monitored for each breeding pair. Disposable and standard cages were maintained in the same location during breeding. Environmental parameters included intracage temperature, humidity, and ammonia and carbon dioxide levels and room light intensity and sound. Overall, 776 offspring were produced. Breeding performance did not differ significantly between the 2 cage types. By 11 wk of age, the weights of pups from both cage types were equivalent. The intracage temperature was 1.1 °F warmer and light intensity at the site of the nest was 34 lx dimmer in disposable cages than in standard caging. The difference in lighting likely was due to nest location; the nests in the disposable cages were at the back of the cages and away from the anterior air supply, whereas in standard caging, nests were at the front of the cages, with the air supply at the rear. Under these husbandry conditions, mice housed in disposable caging systems have comparable breeding performance to those housed in standard individually ventilated cages. PMID:23849403

  14. Building America Case Study: Sealed Crawl Spaces with Integrated Whole-House Ventilation in a Cold Climate, Ithaca, New York

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    "9One method of code-compliance for crawlspaces is to seal and insulate the crawlspace, rather than venting to the outdoors. However, codes require mechanical ventilation; either via conditioned supply air from the HVAC system, or a continuous exhaust ventilation strategy. As the CARB's building partner, Ithaca Neighborhood Housing Services, intended to use the unvented crawlspace in a recent development, CARB was interested in investigating a hybrid ventilation method that includes the exhaust air from the crawlspace as a portion of an ASHRAE 62.2 compliant whole-house ventilation strategy. This hybrid ventilation method was evaluated through a series of long-term monitoring tests thatmore » observed temperature, humidity, and pressure conditions through the home and crawlspace. Additionally, CARB worked with NREL to perform multi-point tracer gas testing on six separate ventilation strategies - varying portions of 62.2 required flow supplied by the crawlspace fan and an upstairs bathroom fan. The intent of the tracer gas testing was to identify effective Reciprocal Age of Air (RAoA), which is equivalent to the air change rate in well-mixed zones, for each strategy while characterizing localized infiltration rates in several areas of the home.« less

  15. Technology Solutions Case Study: Evaluation of Ventilation Strategies in New Construction Multifamily Buildings, New York, New York

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2014-09-01

    In multifamily buildings, particularly in the Northeast, exhaust ventilation strategies are the norm as a means of meeting both local exhaust and whole-unit mechanical ventilation rates. The issue of where the "fresh" air is coming from is gaining significance as air-tightness standards for enclosures become more stringent, and the "normal leakage paths through the building envelope" disappear. Consortium for Advanced Residential Buildings researchers have found that the majority of high performance, new construction, multifamily housing in the Northeast use one of four general strategies for ventilation: continuous exhaust only with no designated supply or make-up air source, continuous exhaust withmore » ducted make-up air to apartments, continuous exhaust with supply through a make-up air device integral to the unit HVAC, and continuous exhaust with supply through a passive inlet device, such as a trickle vent. This research effort included several weeks of building pressure monitoring to validate system performance of the different strategies for providing make-up air to apartments.« less

  16. Mechanical ventilation in disaster situations: a new paradigm using the AGILITIES Score System.

    PubMed

    Wilkens, Eric P; Klein, Gary M

    2010-01-01

    The failure of life-critical systems such as mechanical ventilators in the wake of a pandemic or a disaster may result in death, and therefore, state and federal government agencies must have precautions in place to ensure availability, reliability, and predictability through comprehensive preparedness and response plans. All 50 state emergency preparedness response plans were extensively examined for the attention given to the critically injured and ill patient population during a pandemic or mass casualty event. Public health authorities of each state were contacted as well. Nine of 51 state plans (17.6 percent) included a plan or committee for mechanical ventilation triage and management in a pandemic influenza event. All 51 state plans relied on the Centers for Disease Control and Prevention Flu Surge 2.0 spreadsheet to provide estimates for their influenza planning. In the absence of more specific guidance, the authors have developed and provided guidelines recommended for ventilator triage and the implementation of the AGILITIES Score in the event of a pandemic, mass casualty event, or other catastrophic disaster. The authors present and describe the AGILITIES Score Ventilator Triage System and provide related guidelines to be adopted uniformly by government agencies and hospitals. This scoring system and the set ofguidelines are to be used iA disaster settings, such as Hurricane Katrina, and are based on three key factors: relative health, duration of time on mechanical ventilation, and patients' use of resources during a disaster. For any event requiring large numbers of ventilators for patients, the United States is woefully unprepared. The deficiencies in this aspect of preparedness include (1) lack of accountability for physical ventilators, (2) lack of understanding with which healthcare professionals can safely operate these ventilators, (3) lack of understanding from where additional ventilator resources exist, and (4) a triage strategy to provide

  17. [Pediatric home ventilation--practical approach].

    PubMed

    Rath-Wacenovsky, Regina

    2015-09-01

    Out-of-hospital ventilation represents only a marginal area of paediatric therapeutic concepts. In Austria, the proportion of children to be supplied with invasive and non-invasive ventilation increases significantly, together with the challenges of caring for their long-term demands. Neuromuscular diseases accounted for almost the sole indication group. Premature and newborn infants with persistent respiratory failures are an increasing group, needing more extensive care due to additional comorbidities. Children with congenital disorder have often been tracheotomised in order to secure their airway, and non-invasive ventilation as a bridge- or long-term therapy gains in importance more and more. Usually, infants with primary or secondary CNS disorders suffer from respiratory complications and eventually from chronic respiratory insufficiencies during adolescence or young adulthood. Here, invasive or non-invasive ventilation can contribute both to a significant stabilisation of health status and also quality of life. Spirit of research, experience, appropriate support structures, and appropriate networking constitute the most relevant quality- and success criteria for home care.

  18. Ventilation Transport Trade Study for Future Space Suit Life Support Systems

    NASA Technical Reports Server (NTRS)

    Kempf, Robert; Vogel, Matthew; Paul, Heather L.

    2008-01-01

    A new and advanced portable life support system (PLSS) for space suit surface exploration will require a durable, compact, and energy efficient system to transport the ventilation stream through the space suit. Current space suits used by NASA circulate the ventilation stream via a ball-bearing supported centrifugal fan. As NASA enters the design phase for the next generation PLSS, it is necessary to evaluate available technologies to determine what improvements can be made in mass, volume, power, and reliability for a ventilation transport system. Several air movement devices already designed for commercial, military, and space applications are optimized in these areas and could be adapted for EVA use. This paper summarizes the efforts to identify and compare the latest fan and bearing technologies to determine candidates for the next generation PLSS.

  19. A new prototype of an electronic jet-ventilator and its humidification system

    PubMed Central

    Kraincuk, Paul; Kepka, Anton; Ihra, Gerald; Schabernig, Christa; Aloy, Alexander

    1999-01-01

    Background: Adequate humidification in long-term jet ventilation is a critical aspect in terms of clinical safety. Aim: To assess a prototype of an electronic jet-ventilator and its humidification system. Methods: Forty patients with respiratory insufficiency were randomly allocated to one of four groups. The criterion for inclusion in this study was respiratory insufficiency exhibiting a Murray score above 2. The four groups of patients were ventilated with three different respirators and four different humidification systems. Patients in groups A and B received superimposed high-frequency jet ventilation (SHFJV) by an electronic jet-ventilator either with (group A) or without (group B) an additional humidification system. Patients in group C received high-frequency percussive ventilation (HFPV) by a pneumatic high-frequency respirator, using a hot water humidifier for warming and moistening the inspiration gas. Patients in group D received conventional mechanical ventilation using a standard intensive care unit respirator with a standard humidification system. SHFJV and HFPV were used for a period of 100 h (4days). Results: A significantly low inspiration gas temperature was noted in patients in group B, initially (27.2 ± 2.5°C) and after 2 days (28.0 ± 1.6°C) (P < 0.05). The percentage of relative humidity of the inspiration gas in patients in group B was also initially significantly low (69.8 ± 4.1%; P < 0.05) but rose to an average of 98 ± 2.8% after 2 h. The average percentage across all four groups amounted to 98 ± 0.4% after 2 h. Inflammation of the tracheal mucosa was found in patients in group B and the mucosal injury score (MIS) was significantly higher than in all the other groups. Patients in groups A, C and D showed no severe evidence of airway damage, exhibiting adequate values of relative humidity and temperature of the inspired gas. Conclusion: The problems of humidification associated with jet ventilation can be fully prevented by using

  20. Energy and Cost Associated with Ventilating Office Buildings in a Tropical Climate

    PubMed Central

    Rim, Donghyun; Schiavon, Stefano; Nazaroff, William W.

    2015-01-01

    Providing sufficient amounts of outdoor air to occupants is a critical building function for supporting occupant health, well-being and productivity. In tropical climates, high ventilation rates require substantial amounts of energy to cool and dehumidify supply air. This study evaluates the energy consumption and associated cost for thermally conditioning outdoor air provided for building ventilation in tropical climates, considering Singapore as an example locale. We investigated the influence on energy consumption and cost of the following factors: outdoor air temperature and humidity, ventilation rate (L/s per person), indoor air temperature and humidity, air conditioning system coefficient of performance (COP), and cost of electricity. Results show that dehumidification of outdoor air accounts for more than 80% of the energy needed for building ventilation in Singapore’s tropical climate. Improved system performance and/or a small increase in the indoor temperature set point would permit relatively large ventilation rates (such as 25 L/s per person) at modest or no cost increment. Overall, even in a thermally demanding tropical climate, the energy cost associated with increasing ventilation rate up to 25 L/s per person is less than 1% of the wages of an office worker in an advanced economy like Singapore’s. This result implies that the benefits of increasing outdoor air ventilation rate up to 25 L/s per person — which is suggested to provide for productivity increases, lower sick building syndrome symptom prevalence, and reduced sick leave — can be much larger than the incremental cost of ventilation. PMID:25822504

  1. Energy and cost associated with ventilating office buildings in a tropical climate.

    PubMed

    Rim, Donghyun; Schiavon, Stefano; Nazaroff, William W

    2015-01-01

    Providing sufficient amounts of outdoor air to occupants is a critical building function for supporting occupant health, well-being and productivity. In tropical climates, high ventilation rates require substantial amounts of energy to cool and dehumidify supply air. This study evaluates the energy consumption and associated cost for thermally conditioning outdoor air provided for building ventilation in tropical climates, considering Singapore as an example locale. We investigated the influence on energy consumption and cost of the following factors: outdoor air temperature and humidity, ventilation rate (L/s per person), indoor air temperature and humidity, air conditioning system coefficient of performance (COP), and cost of electricity. Results show that dehumidification of outdoor air accounts for more than 80% of the energy needed for building ventilation in Singapore's tropical climate. Improved system performance and/or a small increase in the indoor temperature set point would permit relatively large ventilation rates (such as 25 L/s per person) at modest or no cost increment. Overall, even in a thermally demanding tropical climate, the energy cost associated with increasing ventilation rate up to 25 L/s per person is less than 1% of the wages of an office worker in an advanced economy like Singapore's. This result implies that the benefits of increasing outdoor air ventilation rate up to 25 L/s per person--which is suggested to provide for productivity increases, lower sick building syndrome symptom prevalence, and reduced sick leave--can be much larger than the incremental cost of ventilation.

  2. Particle transport in low-energy ventilation systems. Part 1: theory of steady states.

    PubMed

    Bolster, D T; Linden, P F

    2009-04-01

    Many modern low-energy ventilation schemes, such as displacement or natural ventilation, take advantage of temperature stratification in a space, extracting the warmest air from the top of the room. The adoption of these energy-efficient ventilation systems still requires the provision of acceptable indoor air quality. In this work we study the steady state transport of particulate contaminants in a displacement-ventilated space. Representing heat sources as ideal sources of buoyancy, analytical models are developed that allow us to compare the average efficiency of contaminant removal between traditional and modern low-energy systems. We found that on average traditional and low-energy systems are similar in overall pollutant removal efficiency, although quite different vertical distributions of contaminant can exist, thus affecting individual exposure. While the main focus of this work is on particles where the dominant mode of deposition is by gravitational settling, we also discuss additional deposition mechanisms and show that the qualitative observations we make carry over to cases where such mechanisms must be included. We illustrate that while average concentration of particles for traditional mixing systems and low energy displacement systems are similar, local concentrations can vary significantly with displacement systems. Depending on the source of the particles this can be better or worse in terms of occupant exposure and engineers should take due diligence accordingly when designing ventilation systems.

  3. Using a Ventilation Controller to Optimize Residential Passive Ventilation For Energy and Indoor Air Quality

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Turner, William; Walker, Iain

    One way to reduce the energy impact of providing residential ventilation is to use passive and hybrid systems. However, these passive and hybrid (sometimes called mixed-mode) systems must still meet chronic and acute health standards for ventilation. This study uses a computer simulation approach to examine the energy and indoor air quality (IAQ) implications of passive and hybrid ventilation systems, in 16 California climate zones. Both uncontrolled and flow controlled passive stacks are assessed. A new hybrid ventilation system is outlined that uses an intelligent ventilation controller to minimise energy use, while ensuring chronic and acute IAQ standards are met.more » ASHRAE Standard 62.2-2010 – the United States standard for residential ventilation - is used as the chronic standard, and exposure limits for PM 2.5, formaldehyde and NO 2 are used as the acute standards.The results show that controlled passive ventilation and hybrid ventilation can be used in homes to provide equivalent IAQ to continuous mechanical ventilation, for less use of energy.« less

  4. Ventilator-Related Adverse Events: A Taxonomy and Findings From 3 Incident Reporting Systems.

    PubMed

    Pham, Julius Cuong; Williams, Tamara L; Sparnon, Erin M; Cillie, Tam K; Scharen, Hilda F; Marella, William M

    2016-05-01

    In 2009, researchers from Johns Hopkins University's Armstrong Institute for Patient Safety and Quality; public agencies, including the FDA; and private partners, including the Emergency Care Research Institute and the University HealthSystem Consortium (UHC) Safety Intelligence Patient Safety Organization, sought to form a public-private partnership for the promotion of patient safety (P5S) to advance patient safety through voluntary partnerships. The study objective was to test the concept of the P5S to advance our understanding of safety issues related to ventilator events, to develop a common classification system for categorizing adverse events related to mechanical ventilators, and to perform a comparison of adverse events across different adverse event reporting systems. We performed a cross-sectional analysis of ventilator-related adverse events reported in 2012 from the following incident reporting systems: the Pennsylvania Patient Safety Authority's Patient Safety Reporting System, UHC's Safety Intelligence Patient Safety Organization database, and the FDA's Manufacturer and User Facility Device Experience database. Once each organization had its dataset of ventilator-related adverse events, reviewers read the narrative descriptions of each event and classified it according to the developed common taxonomy. A Pennsylvania Patient Safety Authority, FDA, and UHC search provided 252, 274, and 700 relevant reports, respectively. The 3 event types most commonly reported to the UHC and the Pennsylvania Patient Safety Authority's Patient Safety Reporting System databases were airway/breathing circuit issue, human factor issues, and ventilator malfunction events. The top 3 event types reported to the FDA were ventilator malfunction, power source issue, and alarm failure. Overall, we found that (1) through the development of a common taxonomy, adverse events from 3 reporting systems can be evaluated, (2) the types of events reported in each database were related

  5. Particle transport in low-energy ventilation systems. Part 2: Transients and experiments.

    PubMed

    Bolster, D T; Linden, P F

    2009-04-01

    Providing adequate indoor air quality while reducing energy consumption is a must for efficient ventilation system design. In this work, we study the transport of particulate contaminants in a displacement-ventilated space, using the idealized 'emptying filling box' model (P.F. Linden, G.F. Lane-serff and D.A. Smeed (1990) Emptying filling boxes: the fluid mechanics of natural ventilation, J. fluid Mech., 212, 309-335.). In this paper, we focused on transient contaminant transport by modeling three transient contamination scenarios, namely the so called 'step-up', 'step-down', and point source cases. Using analytical integral models and numerical models we studied the transient behavior of each of these three cases. We found that, on average, traditional and low-energy systems can be similar in overall pollutant removal efficiency, although quite different vertical gradients can exist. This plays an important role in estimating occupant exposure to contaminant. A series of laboratory experiments were conducted to validate the developed models. The results presented here illustrate that the source location plays a very important role in the distribution of contaminant concentration for spaces ventilated by low energy displacement-ventilation systems. With these results and the knowledge of typical contaminant sources for a given type of space practitioners can design or select more effective systems for the purpose at hand.

  6. Home mechanical ventilation in Canada: a national survey.

    PubMed

    Rose, Louise; McKim, Douglas A; Katz, Sherri L; Leasa, David; Nonoyama, Mika; Pedersen, Cheryl; Goldstein, Roger S; Road, Jeremy D

    2015-05-01

    No comprehensive Canadian national data describe the prevalence of and service provision for ventilator-assisted individuals living at home, data critical to health-care system planning for appropriate resourcing. Our objective was to generate national data profiling service providers, users, types of services, criteria for initiation and monitoring, ventilator servicing arrangements, education, and barriers to home transition. Eligible providers delivering services to ventilator-assisted individuals (adult and pediatric) living at home were identified by our national provider inventory and referrals from other providers. The survey was administered via a web link from August 2012 to April 2013. The survey response rate was 152/171 (89%). We identified 4,334 ventilator-assisted individuals: an estimated prevalence of 12.9/100,000 population, with 73% receiving noninvasive ventilation (NIV) and 18% receiving intermittent mandatory ventilation (9% not reported). Services were delivered by 39 institutional providers and 113 community providers. We identified variation in initiation criteria for NIV, with polysomnography demonstrating nocturnal hypoventilation (57%), daytime hypercapnia (38%), and nocturnal hypercapnia (32%) as the most common criteria. Various models of ventilator servicing were reported. Most providers (64%) stated that caregiver competency was a prerequisite for home discharge; however, repeated competency assessment and retraining were offered by only 45%. Important barriers to home transition were: insufficient funding for paid caregivers, equipment, and supplies; a shortage of paid caregivers; and negotiating public funding arrangements. Ventilatory support in the community appears well-established, with most individuals managed with NIV. Although caregiver competency is a prerequisite to discharge, ongoing assessment and retraining were infrequent. Funding and caregiver availability were important barriers to home transition. Copyright © 2015

  7. A new system for continuous and remote monitoring of patients receiving home mechanical ventilation

    NASA Astrophysics Data System (ADS)

    Battista, L.

    2016-09-01

    Home mechanical ventilation is the treatment of patients with respiratory failure or insufficiency by means of a mechanical ventilator at a patient's home. In order to allow remote patient monitoring, several tele-monitoring systems have been introduced in the last few years. However, most of them usually do not allow real-time services, as they have their own proprietary communication protocol implemented and some ventilation parameters are not always measured. Moreover, they monitor only some breaths during the whole day, despite the fact that a patient's respiratory state may change continuously during the day. In order to reduce the above drawbacks, this work reports the development of a novel remote monitoring system for long-term, home-based ventilation therapy; the proposed system allows for continuous monitoring of the main physical quantities involved during home-care ventilation (e.g., differential pressure, volume, and air flow rate) and is developed in order to allow observations of different remote therapy units located in different places of a city, region, or country. The developed remote patient monitoring system is able to detect various clinical events (e.g., events of tube disconnection and sleep apnea events) and has been successfully tested by means of experimental tests carried out with pulmonary ventilators typically used to support sick patients.

  8. A new system for continuous and remote monitoring of patients receiving home mechanical ventilation.

    PubMed

    Battista, L

    2016-09-01

    Home mechanical ventilation is the treatment of patients with respiratory failure or insufficiency by means of a mechanical ventilator at a patient's home. In order to allow remote patient monitoring, several tele-monitoring systems have been introduced in the last few years. However, most of them usually do not allow real-time services, as they have their own proprietary communication protocol implemented and some ventilation parameters are not always measured. Moreover, they monitor only some breaths during the whole day, despite the fact that a patient's respiratory state may change continuously during the day. In order to reduce the above drawbacks, this work reports the development of a novel remote monitoring system for long-term, home-based ventilation therapy; the proposed system allows for continuous monitoring of the main physical quantities involved during home-care ventilation (e.g., differential pressure, volume, and air flow rate) and is developed in order to allow observations of different remote therapy units located in different places of a city, region, or country. The developed remote patient monitoring system is able to detect various clinical events (e.g., events of tube disconnection and sleep apnea events) and has been successfully tested by means of experimental tests carried out with pulmonary ventilators typically used to support sick patients.

  9. Inhaled Epoprostenol Through Noninvasive Routes of Ventilator Support Systems.

    PubMed

    Ammar, Mahmoud A; Sasidhar, Madhu; Lam, Simon W

    2018-06-01

    The administration of inhaled epoprostenol (iEPO) through noninvasive routes of ventilator support systems has never been previously evaluated. Describe the use of iEPO when administered through noninvasive routes of ventilator support systems. Critically ill patients admitted to the intensive care unit who received iEPO through noninvasive routes were analyzed. Improvements in respiratory status and hemodynamic parameters were evaluated. Safety end points assessed included hypotension, rebound hypoxemia, significant bleeding, and thrombocytopenia. A total of 36 patients received iEPO through noninvasive routes: high-flow oxygen therapy through nasal cannula, n = 29 (81%) and noninvasive positive-pressure ventilation, n = 7 (19%). Sixteen patients had improvement in their respiratory status: mean decrease in fraction of inspired oxygen (FiO 2 ), 20% ± 13%; mean increase in partial pressure of arterial oxygen to FiO 2 (PaO 2 /FiO 2 ) ratio, 60 ± 50 mm Hg; and mean decrease in HFNC oxygen flow rate, 6 ± 3 liters per minute (LPM). Eight patients had declines in their respiratory status (mean increase in FiO 2 , 30% ± 20%; mean decrease in PaO 2 /FiO 2 ratio, 38 ± 20 mm Hg; and mean increase in HFNC oxygen flow rate, 15 ± 10 LPM), and 12 patients had no change in their respiratory status. Conclusion and Relevance: This represents the first evaluation of the administration of iEPO through noninvasive routes of ventilator support systems and demonstrates that in critically ill patients, iEPO could be administered through a noninvasive route. Further evaluation is needed to determine the extent of benefit with this route of administration.

  10. The Anaesthesia Gas Supply System

    PubMed Central

    Das, Sabyasachi; Chattopadhyay, Subhrajyoti; Bose, Payel

    2013-01-01

    The anaesthesia gas supply system is designed to provide a safe, cost-effective and convenient system for the delivery of medical gases at the point of-use. The doctrine of the anaesthesia gas supply system is based on four essential principles: Identity, continuity, adequacy and quality. Knowledge about gas supply system is an integral component of safe anaesthetic practice. Mishaps involving the malfunction or misuse of medical gas supply to operating theatres have cost many lives. The medical gases used in anaesthesia and intensive care are oxygen, nitrous oxide, medical air, entonox, carbon dioxide and heliox. Oxygen is one of the most widely used gases for life-support and respiratory therapy besides anaesthetic procedures. In this article, an effort is made to describe the production, storage and delivery of anaesthetic gases. The design of anaesthesia equipment must take into account the local conditions such as climate, demand and power supply. The operational policy of the gas supply system should have a backup plan to cater to the emergency need of the hospital, in the event of the loss of the primary source of supply. PMID:24249882

  11. Establishment of a total liquid ventilation system using saline-based oxygen micro/nano-bubble dispersions in rats.

    PubMed

    Kakiuchi, Kenta; Matsuda, Kenichi; Harii, Norikazu; Sou, Keitaro; Aoki, Junko; Takeoka, Shinji

    2015-09-01

    Micro/nano-bubbles are practical nanomaterials designed to increase the gas content in liquids. We attempted to use oxygen micro/nano-bubble dispersions as an oxygen-rich liquid as a means for total liquid ventilation. To determine the oxygen content in the bubble dispersion, a new method based on a spectrophotometric change between oxy- and deoxy-hemoglobin was established. The oxygen micro/nano-bubble dispersion was supplied to an experimental total ventilation liquid in anesthetic rats. Though the amount of dissolving oxygen was as low as 6 mg/L in physiological saline, the oxygen content in the oxygen micro/nano-bubble dispersion was increased to 45 mg/L. The positive correlation between the oxygen content and the life-saving time under liquid ventilation clearly indicates that the life-saving time is prolonged by increasing the oxygen content in the oxygen micro/nano-bubble dispersion. This is the first report indicating that the oxygen micro/nano-bubbles containing a sufficient amount of oxygen are useful in producing oxygen-rich liquid for the process of liquid ventilation.

  12. Sensor-based demand controlled ventilation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    De Almeida, A.T.; Fisk, W.J.

    In most buildings, occupancy and indoor pollutant emission rates vary with time. With sensor-based demand-controlled ventilation (SBDCV), the rate of ventilation (i.e., rate of outside air supply) also varies with time to compensate for the changes in pollutant generation. In other words, SBDCV involves the application of sensing, feedback and control to modulate ventilation. Compared to ventilation without feedback, SBDCV offers two potential advantages: (1) better control of indoor pollutant concentrations; and (2) lower energy use and peak energy demand. SBDCV has the potential to improve indoor air quality by increasing the rate of ventilation when indoor pollutant generation ratesmore » are high and occupants are present. SBDCV can also save energy by decreasing the rate of ventilation when indoor pollutant generation rates are low or occupants are absent. After providing background information on indoor air quality and ventilation, this report provides a relatively comprehensive discussion of SBDCV. Topics covered in the report include basic principles of SBDCV, sensor technologies, technologies for controlling air flow rates, case studies of SBDCV, application of SBDCV to laboratory buildings, and research needs. SBDCV appears to be an increasingly attractive technology option. Based on the review of literature and theoretical considerations, the application of SBDCV has the potential to be cost-effective in applications with the following characteristics: (a) a single or small number of dominant pollutants, so that ventilation sufficient to control the concentration of the dominant pollutants provides effective control of all other pollutants; (b) large buildings or rooms with unpredictable temporally variable occupancy or pollutant emission; and (c) climates with high heating or cooling loads or locations with expensive energy.« less

  13. Burbank performs the scheduled extensive cleanup of ventilation systems

    NASA Image and Video Library

    2012-02-22

    ISS030-E-093414 (22 Feb. 2012) --- NASA astronaut Dan Burbank, Expedition 30 commander, performs the scheduled extensive cleanup of ventilation systems in the Columbus laboratory of the International Space Station.

  14. Assessment of Natural Ventilation System for a Typical Residential House in Poland

    NASA Astrophysics Data System (ADS)

    Antczak-Jarząbska, Romana; Krzaczek, Marek

    2016-09-01

    The paper presents the research results of field measurements campaign of natural ventilation performance and effectiveness in a residential building. The building is located in the microclimate whose parameters differ significantly in relation to a representative weather station. The measurement system recorded climate parameters and the physical variables characterizing the air flow in the rooms within 14 days of the winter season. The measurement results showed that in spite of proper design and construction of the ventilation system, unfavorable microclimatic conditions that differed from the predicted ones caused significant reduction in the efficiency of the ventilation system. Also, during some time periods, external climate conditions caused an opposite air flow direction in the vent inlets and outlets, leading to a significant deterioration of air quality and thermal comfort measured by CO2 concentration and PMV index in a residential area.

  15. Water supply rates for recirculating evaporative cooling systems in poultry housing

    USDA-ARS?s Scientific Manuscript database

    Evaporative cooling (EC) is an important tool to reduce heat stress in animal housing systems. Expansion of ventilation capacity in tunnel ventilated poultry facilities has resulted in increased water demand for EC systems. As water resources become more limited and costly, proper planning and des...

  16. Ventilation and ventilators.

    PubMed

    Hayes, B

    1982-01-01

    The history of ventilation is reviewed briefly and recent developments in techniques of ventilation are discussed. Operating features of ventilators have changed in the past few years, partly as the result of clinical progress; yet, technology appears to have outstripped the clinician's ability to harness it most effectively. Clinical discipline and training of medical staff in the use of ventilators could be improved. The future is promising if clinician and designer can work together closely. Ergonomics of ventilators and their controls and the provision of alarms need special attention. Microprocessors are likely to feature prominently in the next generation of designs.

  17. Experimental study of airflow characteristics of stratum ventilation in a multi-occupant room with comparison to mixing ventilation and displacement ventilation.

    PubMed

    Cheng, Y; Lin, Z

    2015-12-01

    The motivation of this study is stimulated by a lack of knowledge about the difference of airflow characteristics between a novel air distribution method [i.e., stratum ventilation (SV)] and conventional air distribution methods [i.e., mixing ventilation (MV) and displacement ventilation (DV)]. Detailed air velocity and temperature measurements were conducted in the occupied zone of a classroom with dimensions of 8.8 m (L) × 6.1 m (W) × 2.4 m (H). Turbulence intensity and power spectrum of velocity fluctuation were calculated using the measured data. Thermal comfort and cooling efficiency were also compared. The results show that in the occupied zone, the airflow characteristics among MV, DV, and SV are different. The turbulent airflow fluctuation is enhanced in this classroom with multiple thermal manikins due to thermal buoyancy and airflow mixing effect. Thermal comfort evaluations indicate that in comparison with MV and DV, a higher supply air temperature should be adopted for SV to achieve general thermal comfort with low draft risk. Comparison of the mean air temperatures in the occupied zone reveals that SV is of highest cooling efficiency, followed by DV and then MV. This study reports the unique profiles of flow, temperature, turbulence intensity, and power spectrum of stratum ventilation, which can have a number of implications for both knowledge and understanding of the flow characteristics in a stratum-ventilated room. With respect to the former, it expounds the fundamental characteristics of this air distribution method; and with respect to the latter, it reveals the mechanism of thermal comfort and energy saving under stratum ventilation. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  18. Space station ventilation study

    NASA Technical Reports Server (NTRS)

    Colombo, G. V.; Allen, G. E.

    1972-01-01

    A ventilation system design and selection method which is applicable to any manned vehicle were developed. The method was used to generate design options for the NASA 33-foot diameter space station, all of which meet the ventilation system design requirements. System characteristics such as weight, volume, and power were normalized to dollar costs for each option. Total system costs for the various options ranged from a worst case $8 million to a group of four which were all approximately $2 million. A system design was then chosen from the $2 million group and is presented in detail. A ventilation system layout was designed for the MSFC space station mockup which provided comfortable, efficient ventilation of the mockup. A conditioned air distribution system design for the 14-foot diameter modular space station, using the same techniques, is also presented. The tradeoff study resulted in the selection of a system which costs $1.9 million, as compared to the alternate configuration which would have cost $2.6 million.

  19. Transport characteristics of expiratory droplets and droplet nuclei in indoor environments with different ventilation airflow patterns.

    PubMed

    Wan, M P; Chao, C Y H

    2007-06-01

    Expiratory droplets and droplet nuclei can be pathogen carriers for airborne diseases. Their transport characteristics were studied in detail in two idealized floor-supply-type ventilation flow patterns: Unidirectional-upward and single-side-floor, using a multiphase numerical model. The model was validated by running interferometric Mie imaging experiments using test droplets with nonvolatile content, which formed droplet nuclei, ultimately, in a class-100 clean-room chamber. By comparing the droplet dispersion and removal characteristics with data of two other ceiling-supply ventilation systems collected from a previous work, deviations from the perfectly mixed ventilation condition were found to exist in various cases to different extent. The unidirectional-upward system was found to be more efficient in removing the smallest droplet nuclei (formed from 1.5 mum droplets) by air extraction, but it became less effective for larger droplets and droplet nuclei. Instead, the single-side-floor system was shown to be more favorable in removing these large droplets and droplet nuclei. In the single-side-floor system, the lateral overall dispersion coefficients for the small droplets and nuclei (initial size system. It indicated that bulk lateral airflow transport in the single-side-floor system was much stronger than the lateral dispersion mechanism induced mainly by air turbulence in the unidirectional-upward system. The time required for the droplets and droplet nuclei to be transported to the exhaust vent or deposition surfaces for removal varied with different ventilation flow patterns. Possible underestimation of exposure level existed if the perfectly mixed condition was assumed. For example, the weak lateral dispersion in the unidirectional ventilation systems made expiratory droplets and droplet nuclei stay at close distance to the source leading to highly nonuniform

  20. Ventilation, temperature, and HVAC characteristics in small and medium commercial buildings in California.

    PubMed

    Bennett, D H; Fisk, W; Apte, M G; Wu, X; Trout, A; Faulkner, D; Sullivan, D

    2012-08-01

    This field study of 37 small and medium commercial buildings throughout California obtained information on ventilation rate, temperature, and heating, ventilating, and air-conditioning (HVAC) system characteristics. The study included seven retail establishments; five restaurants; eight offices; two each of gas stations, hair salons, healthcare facilities, grocery stores, dental offices, and fitness centers; and five other buildings. Fourteen (38%) of the buildings either could not or did not provide outdoor air through the HVAC system. The air exchange rate averaged 1.6 (s.d. = 1.7) exchanges per hour and was similar between buildings with and without outdoor air supplied through the HVAC system, indicating that some buildings have significant leakage or ventilation through open windows and doors. Not all buildings had sufficient air exchange to meet ASHRAE 62.1 Standards, including buildings used for fitness centers, hair salons, offices, and retail establishments. The majority of the time, buildings were within the ASHRAE temperature comfort range. Offices were frequently overcooled in the summer. All of the buildings had filters, but over half the buildings had a filter with a minimum efficiency reporting value rating of 4 or lower, which are not very effective for removing fine particles. Most U.S. commercial buildings (96%) are small- to medium-sized, using nearly 18% of the country's energy, and sheltering a large population daily. Little is known about the ventilation systems in these buildings. This study found a wide variety of ventilation conditions, with many buildings failing to meet relevant ventilation standards. Regulators may want to consider implementing more complete building inspections at commissioning and point of sale. © 2012 John Wiley & Sons A/S.

  1. Ventilating Air-Conditioner

    NASA Technical Reports Server (NTRS)

    Dinh, Khanh

    1994-01-01

    Air-conditioner provides ventilation designed to be used alone or incorporated into cooling or heating system operates efficiently only by recirculating stale air within building. Energy needed to operate overall ventilating cooling or heating system slightly greater than operating nonventilating cooling or heating system. Helps to preserve energy efficiency while satisfying need for increased forced ventilation to prevent accumulation of undesired gases like radon and formaldehyde. Provides fresh treated air to variety of confined spaces: hospital surgeries, laboratories, clean rooms, and printing shops and other places where solvents used. In mobile homes and portable classrooms, eliminates irritant chemicals exuded by carpets, panels, and other materials, ensuring healthy indoor environment for occupants.

  2. Hexavalent chromium and isocyanate exposures during military aircraft painting under crossflow ventilation.

    PubMed

    Bennett, James S; Marlow, David A; Nourian, Fariba; Breay, James; Hammond, Duane

    2016-01-01

    Exposure control systems performance was investigated in an aircraft painting hangar. The ability of the ventilation system and respiratory protection program to limit worker exposures was examined through air sampling during painting of F/A-18C/D strike fighter aircraft, in four field surveys. Air velocities were measured across the supply filter, exhaust filter, and hangar midplane under crossflow ventilation. Air sampling conducted during painting process phases (wipe-down, primer spraying, and topcoat spraying) encompassed volatile organic compounds, total particulate matter, Cr[VI], metals, nitroethane, and hexamethylene diisocyanate, for two worker groups: sprayers and sprayer helpers ("hosemen"). One of six methyl ethyl ketone and two of six methyl isobutyl ketone samples exceeded the short term exposure limits of 300 and 75 ppm, with means 57 ppm and 63 ppm, respectively. All 12 Cr[VI] 8-hr time-weighted averages exceeded the recommended exposure limit of 1 µg/m3, 11 out of 12 exceeded the permissible exposure limit of 5 µg/m3, and 7 out of 12 exceeded the threshold limit value of 10 µg/m3, with means 38 µg/m3 for sprayers and 8.3 µg/m3 for hosemen. Hexamethylene diisocyanate means were 5.95 µg/m3 for sprayers and 0.645 µg/m3 for hosemen. Total reactive isocyanate group--the total of monomer and oligomer as NCO group mass--showed 6 of 15 personal samples exceeded the United Kingdom Health and Safety Executive workplace exposure limit of 20 µg/m3, with means 50.9 µg/m3 for sprayers and 7.29 µg/m3 for hosemen. Several exposure limits were exceeded, reinforcing continued use of personal protective equipment. The supply rate, 94.4 m3/s (200,000 cfm), produced a velocity of 8.58 m/s (157 fpm) at the supply filter, while the exhaust rate, 68.7 m3/s (146,000 cfm), drew 1.34 m/s (264 fpm) at the exhaust filter. Midway between supply and exhaust locations, the velocity was 0.528 m/s (104 fpm). Supply rate exceeding exhaust rate created re

  3. SUBSURFACE VOLATIZATION AND VENTILATION SYSTEM (SVVS) - INNOVATIVE TECHNOLOGY REPORT

    EPA Science Inventory

    This report summarizes the findings associated with a Demonstration Test of Environmental Improvement Technologies’ (EIT) Subsurface Volatilization and Ventilation System (SVVS) process. The technology was evaluated under the EPA Superfund Innovative Technology Evaluation (SITE) ...

  4. Heating, Ventilation and Air-Conditioning Systems, Part of Indoor Air Quality Design Tools for Schools

    EPA Pesticide Factsheets

    The main purposes of a Heating, Ventilation, and Air-Conditioning system are to help maintain good indoor air quality through adequate ventilation with filtration and provide thermal comfort. HVAC systems are among the largest energy consumers in schools.

  5. A taxonomy for mechanical ventilation: 10 fundamental maxims.

    PubMed

    Chatburn, Robert L; El-Khatib, Mohamad; Mireles-Cabodevila, Eduardo

    2014-11-01

    The American Association for Respiratory Care has declared a benchmark for competency in mechanical ventilation that includes the ability to "apply to practice all ventilation modes currently available on all invasive and noninvasive mechanical ventilators." This level of competency presupposes the ability to identify, classify, compare, and contrast all modes of ventilation. Unfortunately, current educational paradigms do not supply the tools to achieve such goals. To fill this gap, we expand and refine a previously described taxonomy for classifying modes of ventilation and explain how it can be understood in terms of 10 fundamental constructs of ventilator technology: (1) defining a breath, (2) defining an assisted breath, (3) specifying the means of assisting breaths based on control variables specified by the equation of motion, (4) classifying breaths in terms of how inspiration is started and stopped, (5) identifying ventilator-initiated versus patient-initiated start and stop events, (6) defining spontaneous and mandatory breaths, (7) defining breath sequences (8), combining control variables and breath sequences into ventilatory patterns, (9) describing targeting schemes, and (10) constructing a formal taxonomy for modes of ventilation composed of control variable, breath sequence, and targeting schemes. Having established the theoretical basis of the taxonomy, we demonstrate a step-by-step procedure to classify any mode on any mechanical ventilator. Copyright © 2014 by Daedalus Enterprises.

  6. Use of a new novel humidification system with high frequency percussive ventilation in a patient with inhalation injury.

    PubMed

    Jones, Samuel W; Short, Kathy A; Joseph, Mark; Sommer, Courtney; Cairns, Bruce A

    2010-01-01

    Historically, it has been difficult to provide adequate humidification delivery with the high frequency percussive ventilator (HFPV) used in many burn centers. It is possible burn centers have avoided using HFPV because of the risk of mucus plugging, dried secretions, and cast formation. Experiences with HFPV provided doubt that the HFPV ventilator circuit could supply adequate humidification to patients receiving this mode of ventilation. Independent gas-flow delivery through the ventilator circuit inherent in HFPV provided a challenge in maintaining adequate humidification delivery to the patient. This report describes a dramatic reduction in dried, inspissated secretions by using a novel new humidification device with HFPV. The new device called the Hydrate Omni (Hydrate, Inc., Midlothian, VA) uses a small ceramic disk to provide fine water particles delivered by a pump to the HFPV circuit. This new device may alleviate previous concerns related to the delivery of adequate humidification with the HFPV. This case report was approved by the University of North Carolina School of Medicine Institutional Review Board.

  7. Effect of frequency of ventilator circuit changes (3 vs 7 days) on the rate of ventilator-associated pneumonia in PICU.

    PubMed

    Samransamruajkit, Rujipat; Jirapaiboonsuk, Suree; Siritantiwat, Sirirush; Tungsrijitdee, Ornanong; Deerojanawong, Jitladda; Sritippayawan, Suchada; Prapphal, Nuanchan

    2010-03-01

    Ventilator-associated pneumonia (VAP) is associated with significant morbidity and mortality in pediatric intensive care unit (PICU). Our purpose was to evaluate the effects of ventilator circuit change on the rate of VAP in the PICU. A prospective randomized controlled trial was conducted at a university hospital PICU. Children (younger than 18 years) who received mechanical ventilation from December 2006 to November 2007 were randomly assigned to receive ventilator circuit changes every 3 or 7 days. Of 176 patients, 88 were assigned to receive ventilator circuit every 3 days and 88 patients had a change weekly. The rate of VAP was 13.9/1000 ventilator days for the 3-day circuit change (n = 12) vs 11.5/1000 ventilator days (n = 10) for the 7-day circuit change (odds ratio, 0.8; confidence interval, 0.3-1.9; P = .6). There was a trend toward decreased PICU stay and mortality rate in 7-day change group compared to 3-day change group but did not reach statistical significance. Furthermore, switching from a 3-day to a 7-day change policy could save costs up to US $22,000/y. The 7-day ventilator circuit change did not contribute to increased rates of VAP in our PICU. Thus, it may be used as a guide to save workload and supply costs. Crown Copyright 2010. Published by Elsevier Inc. All rights reserved.

  8. SITE TECHNOLOGY CAPSULE: SUBSURFACE VOLATILIZATION AND VENTILATION SYSTEM (SVVS)

    EPA Science Inventory

    The Subsurface Volatilization and Ventilation System is an integrated technology used for attacking all phases of volatile organic compound (VOC) contamination in soil and groundwater. The SVVS technology promotes insitu remediation of soil and groundwater contaminated with or-ga...

  9. 24 CFR 3285.605 - Fuel supply system.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 5 2012-04-01 2012-04-01 false Fuel supply system. 3285.605... URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Ductwork and Plumbing and Fuel Supply Systems § 3285.605 Fuel supply system. (a) Proper supply pressure. The gas piping system in the home is...

  10. Harnessing natural ventilation benefits.

    PubMed

    O'Leary, John

    2013-04-01

    Making sure that a healthcare establishment has a good supply of clean fresh air is an important factor in keeping patients, staff, and visitors, free from the negative effects of CO2 and other contaminants. John O'Leary of Trend Controls, a major international supplier of building energy management solutions (BEMS), examines the growing use of natural ventilation, and the health, energy-saving, and financial benefits, that it offers.

  11. 46 CFR 154.1205 - Mechanical ventilation system: Standards.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... openings to accommodations, service, control station, and other gas-safe spaces. (c) Each ventilation system under § 154.1200 (a) and (b)(1) must change the air in that space and its adjoining trunks at... top of each space that personnel enter during cargo handling operations. (b) The discharge end of each...

  12. 7. DETAIL, VENTILATION SYSTEM; EAST FRONT OF QUARANTINE GREENHOUSE #3 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. DETAIL, VENTILATION SYSTEM; EAST FRONT OF QUARANTINE GREENHOUSE #3 (BUILDING 31) - U.S. Plant Introduction Station, Quarantine Headhouses & Greenhouses, 11601 Old Pond Road, Glenn Dale, Prince George's County, MD

  13. A microprocessor-controlled tracheal insufflation-assisted total liquid ventilation system.

    PubMed

    Parker, James Courtney; Sakla, Adel; Donovan, Francis M; Beam, David; Chekuri, Annu; Al-Khatib, Mohammad; Hamm, Charles R; Eyal, Fabien G

    2009-09-01

    A prototype time cycled, constant volume, closed circuit perfluorocarbon (PFC) total liquid ventilator system is described. The system utilizes microcontroller-driven display and master control boards, gear motor pumps, and three-way solenoid valves to direct flow. A constant tidal volume and functional residual capacity (FRC) are maintained with feedback control using end-expiratory and end-inspiratory stop-flow pressures. The system can also provide a unique continuous perfusion (bias flow, tracheal insufflation) through one lumen of a double-lumen endotracheal catheter to increase washout of dead space liquid. FRC and arterial blood gases were maintained during ventilation with Rimar 101 PFC over 2-3 h in normal piglets and piglets with simulated pulmonary edema induced by instillation of albumin solution. Addition of tracheal insufflation flow significantly improved the blood gases and enhanced clearance of instilled albumin solution during simulated edema.

  14. Methane emissions and airflow patterns along longwall faces and through bleeder ventilation systems

    PubMed Central

    Schatzel, Steven J.; Dougherty, Heather N.

    2015-01-01

    The National Institute for Occupational Safety and Health (NIOSH) conducted an investigation of longwall face and bleeder ventilation systems using tracer gas experiments and computer network ventilation. The condition of gateroad entries, along with the caved material’s permeability and porosity changes as the longwall face advances, determine the resistance of the airflow pathways within the longwall’s worked-out area of the bleeder system. A series of field evaluations were conducted on a four-panel longwall district. Tracer gas was released at the mouth of the longwall section or on the longwall face and sampled at various locations in the gateroads inby the shield line. Measurements of arrival times and concentrations defined airflow/gas movements for the active/completed panels and the bleeder system, providing real field data to delineate these pathways. Results showed a sustained ability of the bleeder system to ventilate the longwall tailgate corner as the panels retreated. PMID:26925166

  15. Summary of human responses to ventilation.

    PubMed

    Seppänen, O A; Fisk, W J

    2004-01-01

    It is known that ventilation is necessary to remove indoor-generated pollutants from indoor air or dilute their concentration to acceptable levels. But as the limit values of all pollutants are not known the exact determination of required ventilation rates based on pollutant concentrations is seldom possible. The selection of ventilation rates has to be based also on epidemiological research, laboratory and field experiments and experience. The existing literature indicates that ventilation has a significant impact on several important human outcomes including: (1) communicable respiratory illnesses; (2) sick building syndrome symptoms; (3) task performance and productivity, and (4) perceived air quality (PAQ) among occupants or sensory panels (5) respiratory allergies and asthma. In many studies, prevalence of sick building syndrome symptoms has also been associated with characteristics of HVAC-systems. Often the prevalence of SBS symptoms is higher in air-conditioned buildings than in naturally ventilated buildings. The evidence suggests that better hygiene, commissioning, operation and maintenance of air handling systems may be particularly important for reducing the negative effects of HVAC systems. Ventilation may also have harmful effects on indoor air quality and climate if not properly designed, installed, maintained and operated. Ventilation may bring indoors harmful substances or deteriorate indoor environment. Ventilation interacts also with the building envelope and may deteriorate the structures of the building. Ventilation changes the pressure differences across the structures of building and may cause or prevent infiltration of pollutants from structures or adjacent spaces. Ventilation is also in many cases used to control the thermal environment or humidity in buildings. The paper summarises the current knowledge on positive and negative effects of ventilation on health and other human responses. The focus is on office-type working environment and

  16. Contaminants in ventilated filling boxes

    NASA Astrophysics Data System (ADS)

    Bolster, D. T.; Linden, P. F.

    While energy efficiency is important, the adoption of energy-efficient ventilation systems still requires the provision of acceptable indoor air quality. Many low-energy systems, such as displacement or natural ventilation, rely on temperature stratification within the interior environment, always extracting the warmest air from the top of the room. Understanding buoyancy-driven convection in a confined ventilated space is key to understanding the flow that develops with many of these modern low-energy ventilation schemes. In this work we study the transport of an initially uniformly distributed passive contaminant in a displacement-ventilated space. Representing a heat source as an ideal sourced of buoyancy, analytical and numerical models are developed that allow us to compare the average efficiency of contaminant removal between traditional mixing and modern low-energy systems. A set of small-scale analogue laboratory experiments was also conducted to further validate our analytical and numerical solutions.We find that on average traditional and low-energy ventilation methods are similar with regard to pollutant flushing efficiency. This is because the concentration being extracted from the system at any given time is approximately the same for both systems. However, very different vertical concentration gradients exist. For the low-energy system, a peak in contaminant concentration occurs at the temperature interface that is established within the space. This interface is typically designed to sit at some intermediate height in the space. Since this peak does not coincide with the extraction point, displacement ventilation does not offer the same benefits for pollutant flushing as it does for buoyancy removal.

  17. Control systems for heating, ventilating, and air conditioning

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Haines, R.W.

    1977-01-01

    Hundreds of ideas for designing and controlling sophisticated heating, ventilating and air conditioning (HVAC) systems are presented. Information is included on enthalpy control, energy conservation in HVAC systems, on solar heating, cooling and refrigeration systems, and on a self-draining water collector and heater. Computerized control systems and the economics of supervisory systems are discussed. Information is presented on computer system components, software, relevant terminology, and computerized security and fire reporting systems. Benefits of computer systems are explained, along with optimization techniques, data management, maintenance schedules, and energy consumption. A bibliography, glossaries of HVAC terminology, abbreviations, symbols, and a subject indexmore » are provided. (LCL)« less

  18. Operating theatre ventilation systems and microbial air contamination in total joint replacement surgery: results of the GISIO-ISChIA study.

    PubMed

    Agodi, A; Auxilia, F; Barchitta, M; Cristina, M L; D'Alessandro, D; Mura, I; Nobile, M; Pasquarella, C

    2015-07-01

    Recent studies have shown a higher rate of surgical site infections in hip prosthesis implantation using unidirectional airflow ventilation compared with turbulent ventilation. However, these studies did not measure the air microbial quality of operating theatres (OTs), and assumed it to be compliant with the recommended standards for this ventilation technique. To evaluate airborne microbial contamination in OTs during hip and knee replacement surgery, and compare the findings with values recommended for joint replacement surgery. Air samplings were performed in 28 OTs supplied with unidirectional, turbulent and mixed airflow ventilation. Samples were collected using passive sampling to determine the index of microbial air contamination (IMA). Active sampling was also performed in some of the OTs. The average number of people in the OT and the number of door openings during the sampling period were recorded. In total, 1228 elective prosthesis procedures (60.1% hip and 39.9% knee) were included in this study. Of passive samplings performed during surgical activity in unidirectional airflow ventilation OTs (U-OTs) and mixed airflow OTs (M-OTs), 58.9% and 87.6% had IMA values >2, respectively. Of samplings performed during surgical activity in turbulent airflow OTs (T-OTs) and in turbulent airflow OTs with the surgical team wearing Steri-Shield Turbo Helmets (TH-OTs), 8.6% and 60% had IMA values ≤ 2, respectively. Positive correlation was found between IMA values and the number of people in the OT and the number of door openings (P < 0.001). In addition, correlation was found between active and passive sampling (P < 0.001). These findings challenge the belief that unidirectional systems always provide acceptable airborne bacterial counts. Copyright © 2015 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

  19. Building Component Maintenance and Repair Data Base: Heating, Ventilating, and Air Conditioning (HVAC) Systems

    DTIC Science & Technology

    1991-05-01

    Building Component Maintenance and Repair Data Base: Heating, Ventilating, and Air Conditioning (HVAC) Systems by Edgar S. Neely Robert D. Neathammer...Repair Data Base: Heating, Ventilating, and Air Conditioning (HVAC) Systems RDTE dated 1980EIMB 1984 - 1989 6. AUTHOR(S) Edgar S. Neely, Robert D...Laboratory (USACERL). The Principal Investigators were Dr. Edgar Neely and Mr. Robert Neathammer (USACERL-FS). The primary contractor for much of the

  20. The effect of closed system suction on airway pressures when using the Servo 300 ventilator.

    PubMed

    Frengley, R W; Closey, D N; Sleigh, J W; Torrance, J M

    2001-12-01

    To measure airway pressures during closed system suctioning with the ventilator set to three differing modes of ventilation. Closed system suctioning was conducted in 16 patients following cardiac surgery. Suctioning was performed using a 14 French catheter with a vacuum level of -500 cmH2O through an 8.0 mm internal diameter endotracheal tube. The lungs were mechanically ventilated with a Servo 300 ventilator set to one of three ventilation modes: volume-control, pressure-control or CPAP/pressure support. Airway pressures were measured via a 4 French electronic pressure transducer in both proximal and distal airways. Following insertion of the suction catheter, end-expiratory pressure increased significantly (p < 0.001) in both pressure-control and volume-control ventilation. This increase was greatest (p = 0.018) in volume-control mode (2.7 +/- 1.7 cmH2O). On performing a five second suction, airway pressure decreased in all modes, however the lowest airway pressure in volume-control mode (-4.9 +/- 4.0 cmH2O) was significantly (p = 0.001) less than the lowest airway pressure recorded in either pressure-control (0.8 +/- 1.9 cmH2O) or CPAP/pressure support (0.4 +/- 2.8 cmH2O) modes. In CPAP/pressure support mode, 13 of the 16 patients experienced a positive pressure 'breath' at the end of suctioning with airway pressures rising to 21 +/- 1.6 cmH2O. Closed system suctioning in volume control ventilation may result in elevations of end-expiratory pressure following catheter insertion and subatmospheric airway pressures during suctioning. Pressure control ventilation produces less elevation of end-expiratory pressure following catheter insertion and is less likely to be associated with subatmospheric airway pressures during suctioning. CPAP/pressure support has no effect on end-expiratory pressure following catheter insertion and subatmospheric airway pressures are largely avoided during suctioning.

  1. Building America Case Study: Evaluation of Ventilation Strategies in New Construction Multifamily Buildings, New York, New York (Fact Sheet)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    2014-09-01

    In multifamily buildings, particularly in the Northeast, exhaust ventilation strategies are the norm as a means of meeting both local exhaust and whole-unit mechanical ventilation rates. The issue of where the 'fresh' air is coming from is gaining significance as air-tightness standards for enclosures become more stringent, and the 'normal leakage paths through the building envelope' disappear. CARB researchers have found that the majority of high performance, new construction, multifamily housing in the Northeast use one of four general strategies for ventilation: continuous exhaust only with no designated supply or make-up air source, continuous exhaust with ducted make-up air tomore » apartments, continuous exhaust with supply through a make-up air device integral to the unit HVAC, and continuous exhaust with supply through a passive inlet device, such as a trickle vent. Insufficient information is available to designers on how these various systems are best applied. Product performance data are based on laboratory tests, and the assumption is that products will perform similarly in the field. Proper application involves matching expected performance at expected building pressures, but there is no guarantee that those conditions will exist consistently in the finished building. This research effort, which included several weeks of building pressure monitoring, sought to provide field validation of system performance. The performance of four substantially different strategies for providing make-up air to apartments was evaluated.« less

  2. Hexavalent Chromium and Isocyanate Exposures during Military Aircraft Painting under Crossflow Ventilation

    PubMed Central

    Bennett, James S.; Marlow, David A.; Nourian, Fariba; Breay, James; Hammond, Duane

    2016-01-01

    Exposure control systems performance was investigated in an aircraft painting hangar. The ability of the ventilation system and respiratory protection program to limit worker exposures was examined through air sampling during painting of F/A-18C/D strike fighter aircraft, in four field surveys. Air velocities were measured across the supply filter, exhaust filter, and hangar midplane under crossflow ventilation. Air sampling conducted during painting process phases (wipe-down, primer spraying, and topcoat spraying) encompassed volatile organic compounds, total particulate matter, Cr[VI], metals, nitroethane, and hexamethylene diisocyanate, for two worker groups: sprayers and sprayer helpers (“hosemen”). One of six methyl ethyl ketone and two of six methyl isobutyl ketone samples exceeded the short term exposure limits of 300 and 75 ppm, with means 57 ppm and 63 ppm, respectively. All 12 Cr[VI] 8-hr time-weighted averages exceeded the recommended exposure limit of 1 µg/m3, 11 out of 12 exceeded the permissible exposure limit of 5 µg/m3, and 7 out of 12 exceeded the threshold limit value of 10 µg/m3, with means 38 µg/m3 for sprayers and 8.3 µg/m3 for hosemen. Hexamethylene diisocyanate means were 5.95 µg/m3 for sprayers and 0.645 µg/m3 for hosemen. Total reactive isocyanate group—the total of monomer and oligomer as NCO group mass—showed six of 15 personal samples exceeded the United Kingdom Health and Safety Executive workplace exposure limit of 20 µg/m3, with means 50.9 µg/m3 for sprayers and 7.29 µg/m3 for hosemen. Several exposure limits were exceeded, reinforcing continued use of personal protective equipment. The supply rate, 94.4 m3/s (200,000 cfm), produced a velocity of 8.58 m/s (157 fpm) at the supply filter, while the exhaust rate, 68.7 m3/s (146,000 cfm), drew 1.34 m/s (264 fpm) at the exhaust filter. Midway between supply and exhaust locations, the velocity was 0.528 m/s (104 fpm). Supply rate exceeding exhaust rate created re

  3. Clinical challenges in mechanical ventilation.

    PubMed

    Goligher, Ewan C; Ferguson, Niall D; Brochard, Laurent J

    2016-04-30

    Mechanical ventilation supports gas exchange and alleviates the work of breathing when the respiratory muscles are overwhelmed by an acute pulmonary or systemic insult. Although mechanical ventilation is not generally considered a treatment for acute respiratory failure per se, ventilator management warrants close attention because inappropriate ventilation can result in injury to the lungs or respiratory muscles and worsen morbidity and mortality. Key clinical challenges include averting intubation in patients with respiratory failure with non-invasive techniques for respiratory support; delivering lung-protective ventilation to prevent ventilator-induced lung injury; maintaining adequate gas exchange in severely hypoxaemic patients; avoiding the development of ventilator-induced diaphragm dysfunction; and diagnosing and treating the many pathophysiological mechanisms that impair liberation from mechanical ventilation. Personalisation of mechanical ventilation based on individual physiological characteristics and responses to therapy can further improve outcomes. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Change-over natural and mechanical ventilation system energy consumption in single-family buildings

    NASA Astrophysics Data System (ADS)

    Kostka, Maria; Szulgowska-Zgrzywa, Małgorzata

    2017-11-01

    The parameters of the outside air in Poland cause that in winter it is reasonable to use a mechanical ventilation equipped with a heat recovery exchanger. The time of spring, autumn, summer evenings and nights are often characterized by the parameters of the air, which allow for a natural ventilation and reduce the electricity consumption. The article presents the possibilities of energy consumption reduction for three energy standards of buildings located in Poland, ventilated by a change-over hybrid system. The analysis was prepared on the assumption that the air-to-water heat pump is the heat source for the buildings.

  5. Enhanced deep ocean ventilation and oxygenation with global warming

    NASA Astrophysics Data System (ADS)

    Froelicher, T. L.; Jaccard, S.; Dunne, J. P.; Paynter, D.; Gruber, N.

    2014-12-01

    Twenty-first century coupled climate model simulations, observations from the recent past, and theoretical arguments suggest a consistent trend towards warmer ocean temperatures and fresher polar surface oceans in response to increased radiative forcing resulting in increased upper ocean stratification and reduced ventilation and oxygenation of the deep ocean. Paleo-proxy records of the warming at the end of the last ice age, however, suggests a different outcome, namely a better ventilated and oxygenated deep ocean with global warming. Here we use a four thousand year global warming simulation from a comprehensive Earth System Model (GFDL ESM2M) to show that this conundrum is a consequence of different rates of warming and that the deep ocean is actually better ventilated and oxygenated in a future warmer equilibrated climate consistent with paleo-proxy records. The enhanced deep ocean ventilation in the Southern Ocean occurs in spite of increased positive surface buoyancy fluxes and a constancy of the Southern Hemisphere westerly winds - circumstances that would otherwise be expected to lead to a reduction in deep ocean ventilation. This ventilation recovery occurs through a global scale interaction of the Atlantic Meridional Overturning Circulation undergoing a multi-centennial recovery after an initial century of transient decrease and transports salinity-rich waters inform the subtropical surface ocean to the Southern Ocean interior on multi-century timescales. The subsequent upwelling of salinity-rich waters in the Southern Ocean strips away the freshwater cap that maintains vertical stability and increases open ocean convection and the formation of Antarctic Bottom Waters. As a result, the global ocean oxygen content and the nutrient supply from the deep ocean to the surface are higher in a warmer ocean. The implications for past and future changes in ocean heat and carbon storage will be discussed.

  6. Inspiratory capacity at inflation hold in ventilated newborns: a surrogate measure for static compliance of the respiratory system.

    PubMed

    Hentschel, Roland; Semar, Nicole; Guttmann, Josef

    2012-09-01

    To study appropriateness of respiratory system compliance calculation using an inflation hold and compare it with ventilator readouts of pressure and tidal volume as well as with measurement of compliance of the respiratory system with the single-breath-single-occlusion technique gained with a standard lung function measurement. Prospective clinical trial. Level III neonatal unit of a university hospital. Sixty-seven newborns, born prematurely or at term, ventilated for a variety of pathologic conditions. A standardized sigh maneuver with a predefined peak inspiratory pressure of 30 cm H2O, termed inspiratory capacity at inflation hold, was applied. Using tidal volume, exhaled from inspiratory pause down to ambient pressure, as displayed by the ventilator, and predefined peak inspiratory pressure, compliance at inspiratory capacity at inflation hold conditions could be calculated as well as ratio of tidal volume and ventilator pressure using tidal volume and differential pressure at baseline ventilator settings: peak inspiratory pressure minus positive end-expiratory pressure. For the whole cohort, the equation for the regression between tidal volume at inspiratory capacity at inflation hold and compliance of the respiratory system was: compliance of the respiratory system = 0.052 * tidal volume at inspiratory capacity at inflation hold - 0.113, and compliance at inspiratory capacity at inflation hold conditions was closely related to the standard lung function measurement method of compliance of the respiratory system (R = 0.958). In contrast, ratio of tidal volume and ventilator pressure per kilogram calculated from the ventilator readouts and displayed against compliance of the respiratory system per kilogram yielded a broad scatter throughout the whole range of compliance; both were only weakly correlated (R = 0.309) and also the regression line was significantly different from the line of identity (p < .05). Peak inspiratory pressure at study entry did not

  7. Analysis on ventilation pressure of fire area in longitudinal ventilation of underground tunnel

    NASA Astrophysics Data System (ADS)

    Li, Jiaxin; Li, Yanfeng; Feng, Xiao; Li, Junmei

    2018-03-01

    In order to solve the problem of ventilation pressure loss in the fire area under the fire condition, the wind pressure loss model of the fire area is established based on the thermodynamic equilibrium relation. The semi-empirical calculation formula is obtained by using the model experiment and CFD simulation. The validity of the formula is verified. The results show that the ventilation pressure loss in the fire zone is proportional to the convective heat release rate at the critical velocity, which is inversely proportional to the upstream ventilation velocity and the tunnel cross-sectional area. The proposed formula is consistent with the law of the tunnel fire test fitting formula that results are close, in contrast, the advantage lies in a clear theoretical basis and ventilation velocity values. The resistance of road tunnel ventilation system is calculated accurately and reliably, and then an effective emergency ventilation operation program is developed. It is necessary to consider the fire zone ventilation pressure loss. The proposed ventilation pressure loss formula can be used for design calculation after thorough verification.

  8. [Air quality control systems: heating, ventilating, and air conditioning (HVAC)].

    PubMed

    Bellucci Sessa, R; Riccio, G

    2004-01-01

    After a brief illustration of the principal layout schemes of Heating, Ventilating, and Air Conditioning (HVAC), the first part of this paper summarizes the standards, both voluntary and compulsory, regulating HVAC facilities design and installation with regard to the question of Indoor Air Quality (IAQ). The paper then examines the problem of ventilation systems maintenance and the essential hygienistic requirements in whose absence HVAC facilities may become a risk factor for people working or living in the building. Lastly, the paper deals with HVAC design strategies and methods, which aim not only to satisfy comfort and air quality requirements, but also to ensure easy and effective maintenance procedures.

  9. Cooperation of Horizontal Ground Heat Exchanger with the Ventilation Unit During Summer - Case Study

    NASA Astrophysics Data System (ADS)

    Romańska-Zapała, Anna; Furtak, Marcin; Dechnik, Mirosław

    2017-10-01

    Renewable energy sources are used in the modern energy-efficient buildings to improve their energy balance. One of them is used in the mechanical ventilation system ground air heat exchanger (earth-air heat exchanger - EAHX). This solution, right after heat recovery from exhaust air (recuperation), allows the reduction in the energy needed to obtain the desired temperature of supply air. The article presents the results of "in situ" measurements of pipe ground air heat exchanger cooperating with the air handling unit, supporting cooling the building in the summer season, in Polish climatic conditions. The laboratory consists of a ventilation unit intake - exhaust with rotor for which the source of fresh air is the air intake wall and two air intakes field cooperating with the tube with ground air heat exchangers. Selection of the source of fresh air is performed using sprocket with actuators. This system is part of the ventilation system of the Malopolska Laboratory of Energy-Efficient Building (MLBE) building of Cracow University of Technology. The measuring system are, among others, the sensors of parameters of air inlets and outlets of the heat exchanger channels EAHX and weather station that senses the local weather conditions. The measurement data are recorded and archived by the integrated process control system in the building of MLBE. During the study measurements of operating parameters of the ventilation unit cooperating with the selected source of fresh air were performed. Two cases of operation of the system: using EAHX heat exchanger and without it, were analyzed. Potentially the use of ground air heat exchanger in the mechanical ventilation system can reduce the energy demand for heating or cooling rooms by the pre-adjustment of the supply air temperature. Considering the results can be concluded that the continuous use of these exchangers is not optimal. This relationship is appropriate not only on an annual basis for the transitional periods (spring

  10. Parametric instabilities of rotor-support systems with application to industrial ventilators

    NASA Technical Reports Server (NTRS)

    Parszewski, Z.; Krodkiemski, T.; Marynowski, K.

    1980-01-01

    Rotor support systems interaction with parametric excitation is considered for both unequal principal shaft stiffness (generators) and offset disc rotors (ventilators). Instability regions and types of instability are computed in the first case, and parametric resonances in the second case. Computed and experimental results are compared for laboratory machine models. A field case study of parametric vibrations in industrial ventilators is reported. Computed parametric resonances are confirmed in field measurements, and some industrial failures are explained. Also the dynamic influence and gyroscopic effect of supporting structures are shown and computed.

  11. Hard metal exposures. Part 1: Observed performance of three local exhaust ventilation systems.

    PubMed

    Guffey, S E; Simcox, N; Booth, D W; Hibbard, R; Stebbins, A

    2000-04-01

    Not every ventilation system performs as intended; much can be learned when they do not. The purpose of this study was to compare observed initial performance to expected levels for three saw-reconditioning shop ventilation systems and to characterize the changes in performance of the systems over a one-year period. These three local exhaust ventilation systems were intended to control worker exposures to cobalt, cadmium, and chromium during wet grinding, dry grinding, and welding/brazing activities. Prior to installation the authors provided some design guidance based on Industrial Ventilation, a Manual of Recommended Practice. However, the authors had limited influence on the actual installation and operation and no line authority for the systems. In apparent efforts to cut costs and to respond to other perceived needs, the installed systems deviated from the specifications used in pressure calculations in many important aspects, including adding branch ducts, use of flexible ducts, the choice of fans, and the construction of some hoods. After installation of the three systems, ventilation measurements were taken to determine if the systems met design specifications, and worker exposures were measured to determine effectiveness. The results of the latter will be published as a companion article. The deviations from design and maintenance failures may have adversely affected performance. From the beginning to the end of the study period the distribution of air flow never matched the design specifications for the systems. The observed air flows measured within the first month of installation did not match the predicated design air flows for any of the systems, probably because of the differences between the design and the installed system. Over the first year of operation, hood air flow variability was high due to inadequate cleaning of the sticky process materials which rapidly accumulated in the branch ducts. Poor distribution of air flows among branch ducts

  12. Ventilation performance in the operating theatre against airborne infection: numerical study on an ultra-clean system.

    PubMed

    Chow, T T; Yang, X Y

    2005-02-01

    A laminar airflow study was performed in a standard operating theatre in Hong Kong, the design of which followed the requirements of the UK Health Technical Memorandum. The study of the ultra-clean ventilation system investigated the effectiveness of the laminar flow in: (i) preventing bioaerosols released by the surgical staff from causing postoperative infection of the patient; and (ii) protecting the surgical team against infection by bacteria from the wound site. Seven cases of computer simulation are presented and the sensitivity of individual cases is discussed. Air velocity at the supply diffuser has been identified as one of the most important factors in governing the dispersion of airborne infectious particles. Higher velocity within the laminar regime is advantageous in minimizing the heat-dissipation effect, and to ensure an adequate washing effect against particulate settlement. Inappropriate positioning of the medical lamps can be detrimental. Omission of a partial wall may increase the infection risk of the surgical team due to the ingression of room air at the supply diffuser periphery. This paper stresses that a successful outcome in preventing airborne infection depends as much on resolving human factors as on overcoming technical obstacles.

  13. 46 CFR 105.25-7 - Ventilation systems for cargo tank or pumping system compartment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Ventilation systems for cargo tank or pumping system compartment. 105.25-7 Section 105.25-7 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CARGO AND MISCELLANEOUS VESSELS COMMERCIAL FISHING VESSELS DISPENSING PETROLEUM PRODUCTS Additional Requirements-When Cargo Tanks Are Installed...

  14. 46 CFR 108.437 - Pipe sizes and discharge rates for enclosed ventilation systems for rotating electrical equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Pipe sizes and discharge rates for enclosed ventilation... Systems Fixed Carbon Dioxide Fire Extinguishing Systems § 108.437 Pipe sizes and discharge rates for enclosed ventilation systems for rotating electrical equipment. (a) The minimum pipe size for the initial...

  15. Residential ventilation in the United Kingdom: An overview

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Woolliscroft, M.

    1997-12-31

    This paper describes the background to residential ventilation in the U.K. and its origin in the character of the housing stock, predominantly single-family dwellings and usually terraced or semi-detached but with an increasing proportion of detached houses. Houses in the U.K. have traditionally been leaky by international standards, except by comparison with houses in parts of the US. Current data and trends are presented. Inside temperatures have generally been low by international standards (again recent data are presented), which, combined with high absolute humidity, has led to a major problem of condensation and mold, with the latter affecting several millionmore » dwellings or 17% of the total stock. Thirty-five percent of dwellings are affected by condensation. Residential ventilation in recent years in the U.K. has been largely directed toward this problem. Earlier, when much of the existing stock was actually built, the use of coal fires and leaky dwellings overcame these problems but created other problems. A comparison is made of fuel costs and indoor air temperatures between the U.K. and a number of other countries, and the consequences for the choice of residential ventilation systems are considered. Recent changes in U.K. building regulations are described concerning both ventilation (e.g., extract ventilation from wet areas both active and passive) and insulation and airtightness, and some evidence from the English House Condition Survey (EHCS) and other research on the effects of these changes is presented. Increasing concern about other pollutants--notably nitrogen dioxide (NO{sub 2}), carbon dioxide (CO), and dust mites--is described together with the consequences for combustion appliances, for example. Future problems due to tighter, more highly insulated houses are considered. Some interesting new developments are also considered, such as through-the-wall combined supply and extract units with heat recovery.« less

  16. The impact of cage ventilation on rats housed in IVC systems.

    PubMed

    Krohn, Thomas C; Hansen, Axel Kornerup; Dragsted, Nils

    2003-04-01

    Today the use of individually ventilated cage systems (IVC systems) is common, especially for housing transgenic rodents. Typically, in each cage a ventilation rate of 40 to 50 air changes per hour is applied, but in some systems even up to 120 air changes per hour is applied. To reach this rate, the air is blown into the cage at a relatively high speed. However, at the animal's level most systems ventilate with an air speed of approximately 0.2 m/s. In the present paper, two studies were conducted, one analysing whether an air speed below 0.2 m/s or just above 0.5 m/s affects the rats, and another study analysing whether air changes of 50, 80 and 120 times per hour affect the rats. In both studies, monitoring of preferences as well as physiological parameters such as heart rate and blood pressure, was used to show the ability of the animals to register the different parameters and to avoid them if possible. Air speeds inside the cage of as high as 0.5 m/s could not be shown to affect the rats, while the number of air changes in each cage should be kept below 80 times per hour to avoid impacts on physiology (heart rate and systolic blood pressure). Also the rats prefer cages with air changes below 80 times per hour if they have the opportunity of choosing, as shown in the preference test.

  17. Numerical simulation and comparison of two ventilation methods for a restaurant - displacement vs mixed flow ventilation

    NASA Astrophysics Data System (ADS)

    Chitaru, George; Berville, Charles; Dogeanu, Angel

    2018-02-01

    This paper presents a comparison between a displacement ventilation method and a mixed flow ventilation method using computational fluid dynamics (CFD) approach. The paper analyses different aspects of the two systems, like the draft effect in certain areas, the air temperatureand velocity distribution in the occupied zone. The results highlighted that the displacement ventilation system presents an advantage for the current scenario, due to the increased buoyancy driven flows caused by the interior heat sources. For the displacement ventilation case the draft effect was less prone to appear in the occupied zone but the high heat emissions from the interior sources have increased the temperature gradient in the occupied zone. Both systems have been studied in similar conditions, concentrating only on the flow patterns for each case.

  18. SY Tank Farm ventilation isolation option risk assessment report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Powers, T.B.; Morales, S.D.

    The safety of the 241-SY Tank Farm ventilation system has been under extensive scrutiny due to safety concerns associated with tank 101-SY. Hydrogen and other gases are generated and trapped in the waste below the liquid surface. Periodically, these gases are released into the dome space and vented through the exhaust system. This attention to the ventilation system has resulted in the development of several alternative ventilation system designs. The ventilation system provides the primary means of mitigation of accidents associated with flammable gases. This report provides an assessment of various alternatives ventilation system designs.

  19. 46 CFR 194.20-5 - Ventilation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS HANDLING, USE, AND... Ventilation. (a) Chemical storerooms shall be equipped with a power ventilation system of exhaust type. The... based upon the volume of the compartment. (1) Power ventilation units shall have nonsparking impellers...

  20. Indoor Chemistry: Materials, Ventilation Systems, and Occupant Activities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Morrison, G.C.; Corsi, R.L.; Destaillats, H.

    2006-05-01

    Chemical processes taking place in indoor environments can significantly alter the nature and concentrations of pollutants. Exposure to secondary contaminants generated in these reactions needs to be evaluated in association with many aspects of buildings to minimize their impact on occupant health and well-being. Focusing on indoor ozone chemistry, we describe alternatives for improving indoor air quality by controlling chemical changes related to building materials, ventilation systems, and occupant activities.

  1. Numerical analysis of natural ventilation system in a studio apartment in Bangladesh

    NASA Astrophysics Data System (ADS)

    Kabir, K. M. Ariful; Hasan, Md. Rakibul; Khan, Md. Abdul Hakim

    2017-07-01

    The study of temperature and air flow for natural ventilation system has been investigated numerically. A finite element model for studio apartment was developed with the aim of achieving detail energy allocation in the real buildings during the transient process in the walls and internal air. A tool of computational fluid dynamics (CFD) is employed to assist the process. In the tropical regions most of the energy is consumed by the heating, cooling and ventilation appliances. Therefore, the optimize ventilation system will be a suitable and valid option for the saving of energy from the household sector to increase cooling performance and ensuring thermal comfort as well. A mathematical exploration is carried out on full scale dwelling and small scale model and indication is given on the relevance of such a comparison. Calculations are carried out with household heat sources for calm and windy period, but without any human. As expected, for windy periods, the wind is the main driving force behind the internal air flow. However, in calm periods for unsteady flow the internal airflow looks like more complexes through observation.

  2. Temperature of gas delivered from ventilators.

    PubMed

    Chikata, Yusuke; Onodera, Mutsuo; Imanaka, Hideaki; Nishimura, Masaji

    2013-01-01

    Although heated humidifiers (HHs) are the most efficient humidifying device for mechanical ventilation, some HHs do not provide sufficient humidification when the inlet temperature to the water chamber is high. Because portable and home-care ventilators use turbines, blowers, pistons, or compressors to inhale in ambient air, they may have higher gas temperature than ventilators with piping systems. We carried out a bench study to investigate the temperature of gas delivered from portable and home-care ventilators, including the effects of distance from ventilator outlet, fraction of inspiratory oxygen (FIO2), and minute volume (MV). We evaluated five ventilators equipped with turbine, blower, piston, or compressor system. Ambient air temperature was adjusted to 24°C ± 0.5°C, and ventilation was set at FIO2 0.21, 0.6, and 1.0, at MV 5 and 10 L/min. We analyzed gas temperature at 0, 40, 80, and 120 cm from ventilator outlet and altered ventilator settings. While temperature varied according to ventilators, the outlet gas temperature of ventilators became stable after, at the most, 5 h. Gas temperature was 34.3°C ± 3.9°C at the ventilator outlet, 29.5°C ± 2.2°C after 40 cm, 25.4°C ± 1.2°C after 80 cm and 25.1°C ± 1.2°C after 120 cm (P < 0.01). FIO2 and MV did not affect gas temperature. Gas delivered from portable and home-care ventilator was not too hot to induce heated humidifier malfunctioning. Gas soon declined when passing through the limb.

  3. 46 CFR 154.1205 - Mechanical ventilation system: Standards.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... operational controls outside the ventilated space. (g) No ventilation duct for a gas-dangerous space may pass... Section 154.1205 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and...

  4. 46 CFR 154.1205 - Mechanical ventilation system: Standards.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... operational controls outside the ventilated space. (g) No ventilation duct for a gas-dangerous space may pass... Section 154.1205 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and...

  5. 46 CFR 154.1205 - Mechanical ventilation system: Standards.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... operational controls outside the ventilated space. (g) No ventilation duct for a gas-dangerous space may pass... Section 154.1205 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and...

  6. Chapter 5. Essential equipment, pharmaceuticals and supplies. Recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza epidemic or mass disaster.

    PubMed

    Sprung, Charles L; Kesecioglu, Jozef

    2010-04-01

    To provide recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza pandemic or mass disaster with a specific focus on essential equipment, pharmaceuticals and supplies. Based on a literature review and expert opinion, a Delphi process was used to define the essential topics including essential equipment, pharmaceuticals and supplies. Key recommendations include: (1) ensure that adequate essential medical equipment, pharmaceuticals and important supplies are available during a disaster; (2) develop a communication and coordination system between health care facilities and local/regional/state/country governmental authorities for the provision of additional support; (3) determine the required resources, order and stockpile adequate resources, and judiciously distribute them; (4) acquire additional mechanical ventilators that are portable, provide adequate gas exchange for a range of clinical conditions, function with low-flow oxygen and without high pressure, and are safe for patients and staff; (5) provide advanced ventilatory support and rescue therapies including high levels of inspired oxygen and positive end-expiratory pressure, volume and pressure control ventilation, inhaled nitric oxide, high-frequency ventilation, prone positioning ventilation and extracorporeal membrane oxygenation; (6) triage scarce resources including equipment, pharmaceuticals and supplies based on those who are likely to benefit most or on a 'first come, first served' basis. Judicious planning and adoption of protocols for providing adequate equipment, pharmaceuticals and supplies are necessary to optimize outcomes during a pandemic.

  7. HOW THE LEED VENTILATION CREDIT IMPACTS ENERGY CONSUMPTION OF GSHP SYSTEMS A CASE STUDY FOR PRIMARY SCHOOLS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Xiaobing

    2011-01-01

    This paper presents a study on the impacts of increased outdoor air (OA) ventilation on the performance of ground-source heat pump (GSHP) systems that heat and cool typical primary schools. Four locations Phoenix, Miami, Seattle, and Chicago are selected in this study to represent different climate zones in the United States. eQUEST, an integrated building and HVAC system energy analysis program, is used to simulate a typical primary school and the GSHP system at the four locations with minimum and 30% more than minimum OA ventilation. The simulation results show that, without an energy recovery ventilator, the 30% more OAmore » ventilation results in an 8.0 13.3% increase in total GSHP system energy consumption at the four locations. The peak heating and cooling loads increase by 20.2 30% and 14.9 18.4%, respectively, at the four locations. The load imbalance of the ground heat exchanger is increased in hot climates but reduced in mild and cold climates.« less

  8. A new bipolar Qtrim power supply system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mi, C.; Bruno, D.; Drozd, J.

    2015-05-03

    This year marks the 15th run of RHIC (Relativistic Heavy Ion Collider) operations. The reliability of superconducting magnet power supplies is one of the essential factors in the entire accelerator complex. Besides maintaining existing power supplies and their associated equipment, newly designed systems are also required based on the physicist’s latest requirements. A bipolar power supply was required for this year’s main quadruple trim power supply. This paper will explain the design, prototype, testing, installation and operation of this recently installed power supply system.

  9. Evaluation of ventilators for mouthpiece ventilation in neuromuscular disease.

    PubMed

    Khirani, Sonia; Ramirez, Adriana; Delord, Vincent; Leroux, Karl; Lofaso, Frédéric; Hautot, Solène; Toussaint, Michel; Orlikowski, David; Louis, Bruno; Fauroux, Brigitte

    2014-09-01

    Daytime mouthpiece ventilation is a useful adjunct to nocturnal noninvasive ventilation (NIV) in patients with neuromuscular disease. The aims of the study were to analyze the practice of mouthpiece ventilation and to evaluate the performance of ventilators for mouthpiece ventilation. Practice of mouthpiece ventilation was assessed by a questionnaire, and the performance of 6 home ventilators with mouthpiece ventilation was assessed in a bench test using 24 different conditions per ventilator: 3 mouthpieces, a child and an adult patient profile, and 4 ventilatory modes. Questionnaires were obtained from 30 subjects (mean age 33 ± 11 y) using NIV for 12 ± 7 y. Fifteen subjects used NIV for > 20 h/day, and 11 were totally ventilator-dependent. The subject-reported benefits of mouthpiece ventilation were a reduction in dyspnea (73%) and fatigue (93%) and an improvement in speech (43%) and eating (27%). The bench study showed that none of the ventilators, even those with mouthpiece ventilation software, were able to deliver mouthpiece ventilation without alarms and/or autotriggering in each condition. Alarms and/or ineffective triggering or autotriggering were observed in 135 of the 198 conditions. The occurrence of alarms was more common with a large mouthpiece without a filter compared to a small mouthpiece with a filter (P < .001), but it was not related to the patient profile, the ventilatory mode, or the type of ventilator. Subjects are satisfied with mouthpiece ventilation. Alarms are common with home ventilators, although less common in those with mouthpiece ventilation software. Improvements in home ventilators are needed to facilitate the expansion of mouthpiece ventilation. Copyright © 2014 by Daedalus Enterprises.

  10. Physicochemical Characterization of Nanoparticles from Indoor Ventilation Systems and Their Potential Health Impacts

    NASA Astrophysics Data System (ADS)

    Dalton, G.; Revkin, A. C.; Gruenspecht, H.; Ramanathan, V.; Brown, M. A.; Nagel, D. C.; Revkin, A. C.; Umo, N. S.; Oseghe, E. O.

    2016-12-01

    Indoor air pollution remains a major concern to humans considering that we spend about 90% of our daily lives indoors [1,2]. Air pollutants, which ranges from gases to aerosol particles, vary considerably from our homes, public/work places and confined environments such as cars. They can impact on our health depending on the nature and concentration of the pollutants as well as the duration of exposure [3,4]. Particulate matter (PM), which is one of the major air pollutant markers, is present indoors and can be circulated for days to months within a confined space by the ventilation systems. In this study, both physical and chemical compositional evaluation of PM2.5 - 10 was carried out and the recirculation model of these particulates is presented based on the study of some ventilation systems such as air conditioners, cooling vents, and fans. For the first time, it is shown that the compositional variability of PM does not just depend on the source or the ongoing activities in the confined space but also on the recirculation time. Mineral dust particles were found to be dominant, some mixed with organics and soot or BC particles; heavy metals such as lead (Pb), cadmium (Cd), nickel (Ni), iron (Fe) and others were also analysed from the collected PM. Ventilation systems trap these particulates and do recirculate them over time and this can increase their toxicities and influences their composition. From this study, it can be suggested that regular cleaning of ventilation systems and flushing closed spaces with fresh air may become the most effective ways of controlling the concentration of PM in closed spaces with ventilation units such as indoors and cars. [1] H. K. Lai, et al., Atmospheric Environment 38 (37)(2004). [2] N.E. Klepeis, et al., J. of Exposure Analysis and Environmental Epidemiology 11(2001). [3] N. Bruce, et al., Bul. of the World Health Organization, 78 (9)(2000). [4] K.A. Miller, et al, The New England Journal of Medicine 356 (2007).

  11. Test Protocol for Room-to-Room Distribution of Outside Air by Residential Ventilation Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barley, C. D.; Anderson, R.; Hendron, B.

    2007-12-01

    This test and analysis protocol has been developed as a practical approach for measuring outside air distribution in homes. It has been used successfully in field tests and has led to significant insights on ventilation design issues. Performance advantages of more sophisticated ventilation systems over simpler, less-costly designs have been verified, and specific problems, such as airflow short-circuiting, have been identified.

  12. 6. VIEW LOOKING SOUTHEAST AT VENTILATION EQUIPMENT IN SOUTH VENTILATION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. VIEW LOOKING SOUTHEAST AT VENTILATION EQUIPMENT IN SOUTH VENTILATION HOUSE. THIS AIR CONDITIONING SYSTEM WAS INSTALLED BY PARKS-CRAMER COMPANY OF FITCHBURG, MASSACHUSETTS WHEN THE MILL WAS CONSTRUCTED IN 1923-24. ONE AIR WASHER AND FAN ROOM EXTERIOR IS VISIBLE ON THE RIGHT. THE DUCTS FROM BOTH FAN ROOMS (CURVED METAL STRUCTURES AT CENTER AND LEFT OF PHOTO) ARE CONNECTED TO A COMMON AIR SHAFT. - Stark Mill, 117 Corinth Road, Hogansville, Troup County, GA

  13. Investigation of thermochemical biorefinery sizing and environmental sustainability impacts for conventional supply system and distributed preprocessing supply system designs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Muth, jr., David J.; Langholtz, Matthew H.; Tan, Eric

    2014-03-31

    The 2011 US Billion-Ton Update estimates that by 2030 there will be enough agricultural and forest resources to sustainably provide at least one billion dry tons of biomass annually, enough to displace approximately 30% of the country's current petroleum consumption. A portion of these resources are inaccessible at current cost targets with conventional feedstock supply systems because of their remoteness or low yields. Reliable analyses and projections of US biofuels production depend on assumptions about the supply system and biorefinery capacity, which, in turn, depend upon economic value, feedstock logistics, and sustainability. A cross-functional team has examined combinations of advancesmore » in feedstock supply systems and biorefinery capacities with rigorous design information, improved crop yield and agronomic practices, and improved estimates of sustainable biomass availability. A previous report on biochemical refinery capacity noted that under advanced feedstock logistic supply systems that include depots and pre-processing operations there are cost advantages that support larger biorefineries up to 10 000 DMT/day facilities compared to the smaller 2000 DMT/day facilities. This report focuses on analyzing conventional versus advanced depot biomass supply systems for a thermochemical conversion and refinery sizing based on woody biomass. The results of this analysis demonstrate that the economies of scale enabled by advanced logistics offsets much of the added logistics costs from additional depot processing and transportation, resulting in a small overall increase to the minimum ethanol selling price compared to the conventional logistic supply system. While the overall costs do increase slightly for the advanced logistic supply systems, the ability to mitigate moisture and ash in the system will improve the storage and conversion processes. In addition, being able to draw on feedstocks from further distances will decrease the risk of biomass supply

  14. Mobile communication devices causing interference in invasive and noninvasive ventilators.

    PubMed

    Dang, Bao P; Nel, Pierre R; Gjevre, John A

    2007-06-01

    The aim of this study was to assess if common mobile communication systems would cause significant interference on mechanical ventilation devices and at what distances would such interference occur. We tested all the invasive and noninvasive ventilatory devices used within our region. This consisted of 2 adult mechanical ventilators, 1 portable ventilator, 2 pediatric ventilators, and 2 noninvasive positive pressure ventilatory devices. We operated the mobile devices from the 2 cellular communication systems (digital) and 1 2-way radio system used in our province at varying distances from the ventilators and looked at any interference they created. We tested the 2-way radio system, which had a fixed operation power output of 3.0 watts, the Global Systems for Mobile Communication cellular system, which had a maximum power output of 2.0 watts and the Time Division Multiple Access cellular system, which had a maximum power output of 0.2 watts on our ventilators. The ventilators were ventilating a plastic lung at fixed settings. The mobile communication devices were tested at varying distances starting at zero meter from the ventilator and in all operation modes. The 2-way radio caused the most interference on some of the ventilators, but the maximum distance of interference was 1.0 m. The Global Systems for Mobile Communication system caused significant interference only at 0 m and minor interference at 0.5 m on only 1 ventilator. The Time Division Multiple Access system caused no interference at all. Significant interference consisted of a dramatic rise and fluctuation of the respiratory rate, pressure, and positive end-expiratory pressure of the ventilators with no normalization when the mobile device was removed. From our experiment on our ventilators with the communication systems used in our province, we conclude that mobile communication devices such as cellular phones and 2-way radios are safe and cause no interference unless operated at very close distances of

  15. Visualisation for System Learning in Supply Chains

    ERIC Educational Resources Information Center

    Lindskog, Magnus; Abrahamsson, Mats; Aronsson, Hakan

    2007-01-01

    Contemporary supply chains are vastly complex, and decisions made by actors have system-wide consequences that these might not be able to foresee. There are gaps between "best practice"-founded theory and actual practice in supply chains. To remedy this, we argue, the supply chain actors need to enhance systems knowledge. There is a need to…

  16. Bench performance of ventilators during simulated paediatric ventilation.

    PubMed

    Park, M A J; Freebairn, R C; Gomersall, C D

    2013-05-01

    This study compares the accuracy and capabilities of various ventilators using a paediatric acute respiratory distress syndrome lung model. Various compliance settings and respiratory rate settings were used. The study was done in three parts: tidal volume and FiO2 accuracy; pressure control accuracy and positive end-expiratory pressure (PEEP) accuracy. The parameters set on the ventilator were compared with either or both of the measured parameters by the test lung and the ventilator. The results revealed that none of the ventilators could consistently deliver tidal volumes within 1 ml/kg of the set tidal volume, and the discrepancy between the delivered volume and the volume measured by the ventilator varied greatly. The target tidal volume was 8 ml/kg, but delivered tidal volumes ranged from 3.6-11.4 ml/kg and the volumes measured by the ventilator ranged from 4.1-20.6 ml/kg. All the ventilators maintained pressure within 20% of the set pressure, except one ventilator which delivered pressures of up to 27% higher than the set pressure. Two ventilators maintained PEEP within 10% of the prescribed PEEP. The majority of the readings were also within 10%. However, three ventilators delivered, at times, PEEPs over 20% higher. In conclusion, as lung compliance decreases, especially in paediatric patients, some ventilators perform better than others. This study highlights situations where ventilators may not be able to deliver, nor adequately measure, set tidal volumes, pressure, PEEP or FiO2.

  17. CFD and ventilation research.

    PubMed

    Li, Y; Nielsen, P V

    2011-12-01

    There has been a rapid growth of scientific literature on the application of computational fluid dynamics (CFD) in the research of ventilation and indoor air science. With a 1000-10,000 times increase in computer hardware capability in the past 20 years, CFD has become an integral part of scientific research and engineering development of complex air distribution and ventilation systems in buildings. This review discusses the major and specific challenges of CFD in terms of turbulence modelling, numerical approximation, and boundary conditions relevant to building ventilation. We emphasize the growing need for CFD verification and validation, suggest ongoing needs for analytical and experimental methods to support the numerical solutions, and discuss the growing capacity of CFD in opening up new research areas. We suggest that CFD has not become a replacement for experiment and theoretical analysis in ventilation research, rather it has become an increasingly important partner. We believe that an effective scientific approach for ventilation studies is still to combine experiments, theory, and CFD. We argue that CFD verification and validation are becoming more crucial than ever as more complex ventilation problems are solved. It is anticipated that ventilation problems at the city scale will be tackled by CFD in the next 10 years. © 2011 John Wiley & Sons A/S.

  18. [Anesthesia ventilators].

    PubMed

    Otteni, J C; Beydon, L; Cazalaà, J B; Feiss, P; Nivoche, Y

    1997-01-01

    To review anaesthesia ventilators in current use in France by categories of ventilators. References were obtained from computerized bibliographic search. (Medline), recent review articles, the library of the service and personal files. Anaesthesia ventilators can be allocated into three groups, depending on whether they readminister expired gases or not or allow both modalities. Contemporary ventilators provide either constant volume ventilation, or constant pressure ventilation, with or without a pressure plateau. Ventilators readministering expired gases after CO2 absorption, or closed circuit ventilators, are either of a double- or a single-circuit design. Double-circuit ventilators, or pneumatical bag or bellows squeezers, or bag-in-bottle or bellows-in-bottle (or box) ventilators, consist of a primary, or driving circuit (bottle or box) and a secondary or patient circuit (including a bag or a bellows or membrane chambers). Bellows-in-bottle ventilators have either standing bellows ascending at expiration, or hanging bellows, descending at expiration. Ascending bellows require a positive pressure of about 2 cmH2O throughout exhalation to allow the bellows to refill. The expired gas volume is a valuable indicator for leak and disconnection. Descending bellows generate a slight negative pressure during exhalation. In case of leak or disconnection they aspirate ambient air and cannot act therefore as an indicator for integrity of the circuit and the patient connection. Closed circuit ventilators with a single-circuit (patient circuit) include a insufflating device consisting either in a bellows or a cylinder with a piston, operated by a electric or pneumatic motor. As the hanging bellows of the double circuit ventilators, they generate a slight negative pressure during exhalation and aspirate ambient air in case of leak or disconnection. Ventilators not designed for the readministration of expired gases, or open circuit ventilators, are generally stand

  19. Confined space ventilation by shipyard welders: observed use and effectiveness.

    PubMed

    Pouzou, Jane G; Warner, Chris; Neitzel, Richard L; Croteau, Gerry A; Yost, Michael G; Seixas, Noah S

    2015-01-01

    Shipbuilding involves intensive welding activities within enclosed and confined spaces, and although ventilation is commonly used in the industry, its use and effectiveness has not been adequately documented. Workers engaged in welding in enclosed or confined spaces in two shipyards were observed for their use of ventilation and monitored for their exposure to particulate matter. The type of ventilation in use, its placement and face velocity, the movement of air within the space, and other ventilation-related parameters were recorded, along with task characteristics such as the type of welding, the welder's position, and the configuration of the space. Mechanical ventilation was present in about two-thirds of the 65 welding scenarios observed, with exhaust ventilation used predominantly in one shipyard and supply blowers predominantly in the other. Welders were observed working in apparent dead-spaces within the room in 53% of the cases, even where ventilation was in use. Respiratory protection was common in the two shipyards, observed in use in 77 and 100% of the cases. Welding method, the proximity of the welder's head to the fume, and air mixing were found to be significantly associated with the welder's exposure, while other characteristics of dilution ventilation did not produce appreciable differences in exposure level. These parameters associated with exposure reduction can be assessed subjectively and are thus good candidates for training on effective ventilation use during hot work in confined spaces. Ventilation used in confined space welding is often inadequate for controlling exposure to welding fume. © The Author 2014. Published by Oxford University Press on behalf of the British Occupational Hygiene Society.

  20. Impact of Fire Ventilation on General Ventilation in the Building

    NASA Astrophysics Data System (ADS)

    Zender-Świercz, Ewa; Telejko, Marek

    2017-10-01

    The fire of building is a threat to its users. The biggest threat is generation, during lifetime of fire, hot gases and smoke. The purpose of quick and efficient evacuation from the area covered by the fire, at first step the escape routes have to be secured from smokiness. The smoke ventilation systems are used for this purpose. The proper design and execution of smoke ventilation is important not only because of the safety, but also of the maintenance of comfort in the building at a time when there is no fire. The manuscript presents the effect of incorrectly realized smoke ventilation in the stairwell of the medium building. The analysis shows that the flaps of smoke ventilation located in the stairwell may have a significant impact on the proper functioning of mechanical ventilation in the period when there is no fire. The improperly installed or incorrect insulated components cause perturbation of air flow and they change pressure distribution in the building. The conclusion of the analysis is the need to include the entire technical equipment of the building during the design and realization of its individual elements. The impact of various installations at each other is very important, and the omission of any of them can cause disturbances in the proper work of another.

  1. Advanced COPD patients under home mechanical ventilation and/or long term oxygen therapy: Italian healthcare costs.

    PubMed

    Vitacca, M; Bianchi, L; Bazza, A; Clini, E M

    2011-12-01

    Little information is available on healthcare costs for patients with very severe chronic obstructive pulmonary disease. The aim of the current work was to evaluate Italian healthcare costs in these patients. Prospective 1-year analysis was assessed in three subgroups of patients; non-invasively ventilated (n=30); invasively-ventilated (n=12) and on long-term oxygen therapy (n=41). Acute costs for care were a sum of fees for doctor's consultations, admissions to hospital (ward and intensive care units) and emergency drugs. Chronic costs were the sum of costs for pharmacotherapy and home ventilation and/or oxygen care. Mean cost/day/patient was 96 +/- 112 Euro (range 9-526 Euro), with acute costs accounting for 72% and chronic costs for 28% of the total cost burden, with no significant differences in costs associated with the three subgroups. Acute costs had a non-normal distribution (range 0 to 510 Euro) being cost for hospitalisation the highest cost burden with more than 30% of acute care costs attributed to only a small segment of patients. Chronic care costs were also unevenly distributed among the various groups (ANOVA p = 0.006), being home oxygen supply the highest cost burden. The current Health Care System is in urgent need for a reassessment of the high cost burden associated with hospitalisations and home oxygen supply.

  2. 46 CFR 194.15-5 - Ventilation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ....15-5 Ventilation. (a) Operations, reactions or experiments which produce toxic, noxious or corrosive...) Ventilation of air conditioning systems serving the chemical laboratory shall be designed so that air cannot...

  3. Concept of operations for triage of mechanical ventilation in an epidemic.

    PubMed

    Hick, John L; O'Laughlin, Daniel T

    2006-02-01

    The recent outbreak of severe acute respiratory syndrome and the growing potential of an influenza pandemic force us to consider the fact that despite great advances in critical care medicine, we lack the capacity to provide intensive care to the large number of patients that may be generated in an epidemic or multisite bioterrorism event. Because many epidemic and bioterrorist agent illnesses involve respiratory failure, mechanical ventilation is a frequently required intervention but one that is in limited supply. In advance of such an event, we must develop triage criteria that depend on clinical indicators of survivability and resource utilization to allocate scarce health care resources to those who are most likely to benefit. These criteria must be tiered, flexible, and implemented regionally, rather than institutionally, with the backing of public health agencies and relief of liability. This report provides a sample concept of operations for triage of mechanical ventilation in epidemic situations and discusses some of the ethical principles and pitfalls of such systems.

  4. Assessment of the impact of dipped guideways on urban rail transit systems: Ventilation and safety requirements

    NASA Technical Reports Server (NTRS)

    1982-01-01

    The ventilation and fire safety requirements for subway tunnels with dipped profiles between stations as compared to subway tunnels with level profiles were evaluated. This evaluation is based upon computer simulations of a train fire emergency condition. Each of the tunnel configurations evaluated was developed from characteristics that are representative of modern transit systems. The results of the study indicate that: (1) The level tunnel system required about 10% more station cooling than dipped tunnel systems in order to meet design requirements; and (2) The emergency ventilation requirements are greater with dipped tunnel systems than with level tunnel systems.

  5. [The effect of the ventilation rate on air particle and air microbe concentration in operating rooms with conventional ventilation. 1. Measurement without surgical activity].

    PubMed

    Kruppa, B; Rüden, H

    1993-05-01

    The question was if a reduction of airborne particles and bacteria in conventionally (turbulently), ventilated operating theatres in comparison to Laminar-Airflow (LAF) operating theatres does occur at high air-exchange-rates. Within the framework of energy consumption measures the influence of air-exchange-rates on airborne particle and bacteria concentrations was determined in two identical operating theatres with conventional ventilation (wall diffusor panel) at the air-exchange-rates 7.5, 10, 15 and 20/h without surgical activity. This was established by means of the statistical procedure of analysis of variance. Especially for the comparison of the air-exchange-rates 7.5 and 15/h statistical differences were found for airborne particle concentrations in supply and ambient air. Concerning airborne bacteria concentrations no differences were found among the various air-exchange-rates. Explanation of variance is quite high for non-viable particles (supply air: 37%, ambient air: 81%) but negligible for viable particles (bacteria) with values below 15%.

  6. UKIRT Upgrades Program: design and installation of the Dome Ventilation System (DVS)

    NASA Astrophysics Data System (ADS)

    Neff, D. H.; Hileman, Edward A.; Kain, S. J.; Cavedoni, Charles P.; Chuter, Timothy C.

    1997-03-01

    In order to encourage adequate dome ventilation to reduce or eliminate dome seeing at the 3.8 m United Kingdom Infrared Telescope (UKIRT), a dome ventilation system (DVS) was designed to be installed in the lower dome skirt. The modifications to the dome for the new DVS apertures consisted of installing a reinforcing frame containing an insulated rollup door and adjustable louvers. This paper describes the finite element structural analysis of the reinforcing frame, the detailed design of the frame hardware, the design of the programmable language control (PLC) system for controlling the opening and closing of the rollup doors, and the fabrication and installation of a prototype frame assembly. To date, a prototype assembly has been installed that confirms the design, and fifteen production assemblies are currently under fabrication for installation by September 1996.

  7. Investigation of thermochemical biorefinery sizing and environmental sustainability impacts for conventional supply system and distributed pre-processing supply system designs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    David J. Muth, Jr.; Matthew H. Langholtz; Eric C. D. Tan

    The 2011 US Billion-Ton Update estimates that by 2030 there will be enough agricultural and forest resources to sustainably provide at least one billion dry tons of biomass annually, enough to displace approximately 30% of the country's current petroleum consumption. A portion of these resources are inaccessible at current cost targets with conventional feedstock supply systems because of their remoteness or low yields. Reliable analyses and projections of US biofuels production depend on assumptions about the supply system and biorefinery capacity, which, in turn, depend upon economic value, feedstock logistics, and sustainability. A cross-functional team has examined combinations of advancesmore » in feedstock supply systems and biorefinery capacities with rigorous design information, improved crop yield and agronomic practices, and improved estimates of sustainable biomass availability. A previous report on biochemical refinery capacity noted that under advanced feedstock logistic supply systems that include depots and pre-processing operations there are cost advantages that support larger biorefineries up to 10 000 DMT/day facilities compared to the smaller 2000 DMT/day facilities. This report focuses on analyzing conventional versus advanced depot biomass supply systems for a thermochemical conversion and refinery sizing based on woody biomass. The results of this analysis demonstrate that the economies of scale enabled by advanced logistics offsets much of the added logistics costs from additional depot processing and transportation, resulting in a small overall increase to the minimum ethanol selling price compared to the conventional logistic supply system. While the overall costs do increase slightly for the advanced logistic supply systems, the ability to mitigate moisture and ash in the system will improve the storage and conversion processes. In addition, being able to draw on feedstocks from further distances will decrease the risk of biomass supply

  8. Comfort parameters - Ventilation of a subway wagon

    NASA Astrophysics Data System (ADS)

    Petr, Pavlíček; Ladislav, Tříska

    2017-09-01

    Research and development of a ventilation system is being carried out as a part of project TA04030774 of the Technology Agency of the Czech Republic. Name of the project is "Research and Development of Mass-optimized Components for Rail Vehicles". Problems being solved are development and testing of a new concept for ventilation systems for public transport vehicles. The main improvements should be a reduction of the mass of the whole system, easy installation and reduction of the noise of the ventilation system. This article is focused on the comfort parameters in a subway wagon (measurement and evaluation carried out on a function sample in accordance with the regulations). The input to the project is a ventilator hybrid casing for a subway wagon, which was manufactured and tested during the Ministry of Industry and Trade project TIP FR-TI3/449.

  9. Employing a Modified Diffuser Momentum Model to Simulate Ventilation of the Orion CEV

    NASA Technical Reports Server (NTRS)

    Straus, John; Lewis, John F.

    2011-01-01

    The Ansys CFX CFD modeling tool was used to support the design efforts of the ventilation system for the Orion CEV. CFD modeling was used to establish the flow field within the cabin for several supply configurations. A mesh and turbulence model sensitivity study was performed before the design studies. Results were post-processed for comparison with performance requirements. Most configurations employed straight vaned diffusers to direct and throw the flow. To manage the size of the models, the diffuser vanes were not resolved. Instead, a momentum model was employed to account for the effect of the diffusers. The momentum model was tested against a separate, vane-resolved side study. Results are presented for a single diffuser configuration for a low supply flow case.

  10. Effect of central ventilation and air conditioner system on the concentration and health risk from airborne polycyclic aromatic hydrocarbons.

    PubMed

    Lv, Jinze; Zhu, Lizhong

    2013-03-01

    Central ventilation and air conditioner systems are widely utilized nowadays in public places for air exchange and temperature control, which significantly influences the transfer of pollutants between indoors and outdoors. To study the effect of central ventilation and air conditioner systems on the concentration and health risk from airborne pollutants, a spatial and temporal survey was carried out using polycyclic aromatic hydrocarbons (PAHs) as agent pollutants. During the period when the central ventilation system operated without air conditioning (AC-off period), concentrations of 2-4 ring PAHs in the model supermarket were dominated by outdoor levels, due to the good linearity between indoor air and outdoor air (r(p) > 0.769, p < 0.05), and the slopes (1.2-4.54) indicated that ventilating like the model supermarket increased the potential health risks from low molecular weight PAHs. During the period when the central ventilation and air conditioner systems were working simultaneously (AC-on period), although the total levels of PAHs were increased, the concentrations and percentage of the particulate PAHs indoors declined significantly. The BaP equivalency (BaPeq) concentration indicated that utilization of air conditioning reduced the health risks from PAHs in the model supermarket.

  11. 46 CFR 127.260 - Ventilation for accommodations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Ventilation for accommodations. 127.260 Section 127.260... ARRANGEMENTS Particular Construction and Arrangements § 127.260 Ventilation for accommodations. (a) Each... vessel of 100 or more gross tons must be provided with a mechanical ventilation system unless the...

  12. Microclimate measuring and fluid‑dynamic simulation in an industrial broiler house: testing of an experimental ventilation system.

    PubMed

    Bianchi, Biagio; Giametta, Ferruccio; La Fianza, Giovanna; Gentile, Andrea; Catalano, Pasquale

    2015-01-01

    The environment in the broiler house is a combination of physical and biological factors generating a complex dynamic system of interactions between birds, husbandry system, light, temperature, and the aerial environment. Ventilation plays a key role in this scenario. It is pivotal to remove carbon dioxide and water vapor from the air of the hen house. Adequate ventilation rates provide the most effective method of controlling temperature within the hen house. They allow for controlling the relative humidity and can play a key role in alleviating the negative effects of high stocking density and of wet litter. In the present study the results of experimental tests performed in a breeding broiler farm are shown. In particular the efficiency of a semi transversal ventilation system was studied against the use of a pure transversal one. In order to verify the efficiency of the systems, fluid dynamic simulations were carried out using the software Comsol multiphysics. The results of this study show that a correct architectural and structural design of the building must be supported by a design of the ventilation system able to maintain the environmental parameters within the limits of the thermo‑neutral and welfare conditions and to achieve the highest levels of productivity.

  13. Effect of mechanical ventilation on systemic oxygen extraction and lactic acidosis during early septic shock in rats.

    PubMed

    Griffel, M I; Astiz, M E; Rackow, E C; Weil, M H

    1990-01-01

    We studied the effect of mechanical ventilation on systemic oxygen extraction and lactic acidosis in peritonitis and shock in rats. Sepsis was induced by cecal ligation and perforation. After tracheostomy, rats were randomized to spontaneous breathing (S) or mechanical ventilation with paralysis (V). Five animals were studied in each group. The V animals were paralyzed with pancuronium bromide to eliminate respiratory effort. Mechanical ventilation consisted of controlled ventilation using a rodent respirator with periodic adjustment of minute ventilation to maintain PaCO2 and pH within normal range. Arterial and central venous blood gases and thermodilution cardiac output were measured at baseline before abdominal surgery, and sequentially at 0.5, 3.5, and 6 h after surgery. At 6 h, cardiac output was 193 +/- 30 ml/kg.min in S animals and 199 +/- 32 ml/kg.min in V animals (NS). The central venous oxygen saturation was 27.4 +/- 4.7% in S animals and 30.0 +/- 6.4% in V animals (NS). Systemic oxygen extraction was 70 +/- 5% in S animals and 67 +/- 6% in V animals (NS). Arterial lactate was 2.4 +/- 0.4 mmol/L in S animals and 2.2 +/- 0.5 mmol/L in V animals (NS). The S animals developed lethal hypotension at 6.6 +/- 0.4 h compared to 6.8 +/- 0.4 h in V animals (NS). These data suggest that mechanical ventilation does not decrease systemic oxygen extraction or ameliorate the development of lactic acidosis during septic shock.

  14. System Dynamics Modeling for Supply Chain Information Sharing

    NASA Astrophysics Data System (ADS)

    Feng, Yang

    In this paper, we try to use the method of system dynamics to model supply chain information sharing. Firstly, we determine the model boundaries, establish system dynamics model of supply chain before information sharing, analyze the model's simulation results under different changed parameters and suggest improvement proposal. Then, we establish system dynamics model of supply chain information sharing and make comparison and analysis on the two model's simulation results, to show the importance of information sharing in supply chain management. We wish that all these simulations would provide scientific supports for enterprise decision-making.

  15. An expert system for the design of heating, ventilating, and air-conditioning systems

    NASA Astrophysics Data System (ADS)

    Camejo, Pedro Jose

    1989-12-01

    Expert systems are computer programs that seek to mimic human reason. An expert system shelf, a software program commonly used for developing expert systems in a relatively short time, was used to develop a prototypical expert system for the design of heating, ventilating, and air-conditioning (HVAC) systems in buildings. Because HVAC design involves several related knowledge domains, developing an expert system for HVAC design requires the integration of several smaller expert systems known as knowledge bases. A menu program and several auxiliary programs for gathering data, completing calculations, printing project reports, and passing data between the knowledge bases are needed and have been developed to join the separate knowledge bases into one simple-to-use program unit.

  16. Development of Smart Ventilation Control Algorithms for Humidity Control in High-Performance Homes in Humid U.S. Climates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Less, Brennan; Walker, Iain; Ticci, Sara

    Past field research and simulation studies have shown that high performance homes experience elevated indoor humidity levels for substantial portions of the year in humid climates. This is largely the result of lower sensible cooling loads, which reduces the moisture removed by the cooling system. These elevated humidity levels lead to concerns about occupant comfort, health and building durability. Use of mechanical ventilation at rates specified in ASHRAE Standard 62.2-2013 are often cited as an additional contributor to humidity problems in these homes. Past research has explored solutions, including supplemental dehumidification, cooling system operational enhancements and ventilation system design (e.g.,more » ERV, supply, exhaust, etc.). This project’s goal is to develop and demonstrate (through simulations) smart ventilation strategies that can contribute to humidity control in high performance homes. These strategies must maintain IAQ via equivalence with ASHRAE Standard 62.2-2013. To be acceptable they must not result in excessive energy use. Smart controls will be compared with dehumidifier energy and moisture performance. This work explores the development and performance of smart algorithms for control of mechanical ventilation systems, with the objective of reducing high humidity in modern high performance residences. Simulations of DOE Zero-Energy Ready homes were performed using the REGCAP simulation tool. Control strategies were developed and tested using the Residential Integrated Ventilation (RIVEC) controller, which tracks pollutant exposure in real-time and controls ventilation to provide an equivalent exposure on an annual basis to homes meeting ASHRAE 62.2-2013. RIVEC is used to increase or decrease the real-time ventilation rate to reduce moisture transport into the home or increase moisture removal. This approach was implemented for no-, one- and two-sensor strategies, paired with a variety of control approaches in six humid climates

  17. Ventilation planning at Energy West's Deer Creek mine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tonc, L.; Prosser, B.; Gamble, G.

    2009-08-15

    In 2004 ventilation planning was initiated to exploit a remote area of Deer Creek mine's reserve (near Huntington, Utah), the Mill Fork Area, located under a mountain. A push-pull ventilation system was selected. This article details the design process of the ventilation system upgrade, the procurement process for the new fans, and the new fan startup testing. 5 figs., 1 photo.

  18. Alternatives generation and analysis for double-shell tank primary ventilation systems emissions control and monitoring

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    SEDERBURG, J.P.

    1999-09-30

    This AGA addresses the question: ''What equipment upgrades, operational changes, and/or other actions are required relative to the DST tanks farms' ventilation systems to support retrieval, staging (including feed sampling), and delivery of tank waste to the Phase I private contractor?'' Issues and options for the various components within the ventilation subsystem affect each other. Recommended design requirements are presented and the preferred alternatives are detailed.

  19. Highlighting the importance of transitional ventilation regimes in the management of Mediterranean show caves (Nerja-Pintada system, southern Spain).

    PubMed

    Liñán, C; Del Rosal, Y; Carrasco, F; Vadillo, I; Benavente, J; Ojeda, L

    2018-08-01

    This study shows the utilization of the air CO 2 exhaled by a very high number of visitors in the Nerja Cave as both a tracer and an additional tool to precisely evaluate the air circulation through the entire karst system, which includes non-touristic passages, originally free of anthropogenic CO 2 . The analysis of the temporal - spatial evolution of the CO 2 content and other monitoring data measured from January 2015 to December 2016 in the Nerja-Pintada system, including air microbiological controls, has allowed us to define a new general ventilation model, of great interest for the conservation of the subterranean environment. During the annual cycle four different ventilation regimes and two ventilation modes (UAF-mode and DAF-mode) exist which determine the significance of the anthropogenic impact within the caves. During the winter regime, the strong ventilation regime and the airflow directions from the lowest to the highest entrance (UAF-mode) contribute to the rapid elimination of anthropogenic CO 2 , and this affects the whole karstic system. During the summer regime the DAF-mode ventilation (with airflows from the highest to the lowest entrances) is activated. Although the number of visitors is maximum and the natural ventilation of the karstic system is the lowest of the annual cycle, the anthropogenic impact only affects the Tourist Galleries. The transitional ventilation regimes -spring and autumn- are the most complex of the annual cycle, with changing air-flow directions (from UAF-mode to DAF-mode and vice versa) at diurnal and poly diurnal scale, which conditions the range of the anthropogenic impact in each sector of the karst system. The activation of the DAF-mode has been observed when the temperature difference between the external and air cave is higher than 5°C. Copyright © 2018 Elsevier B.V. All rights reserved.

  20. Modeling sustainability in renewable energy supply chain systems

    NASA Astrophysics Data System (ADS)

    Xie, Fei

    This dissertation aims at modeling sustainability of renewable fuel supply chain systems against emerging challenges. In particular, the dissertation focuses on the biofuel supply chain system design, and manages to develop advanced modeling framework and corresponding solution methods in tackling challenges in sustaining biofuel supply chain systems. These challenges include: (1) to integrate "environmental thinking" into the long-term biofuel supply chain planning; (2) to adopt multimodal transportation to mitigate seasonality in biofuel supply chain operations; (3) to provide strategies in hedging against uncertainty from conversion technology; and (4) to develop methodologies in long-term sequential planning of the biofuel supply chain under uncertainties. All models are mixed integer programs, which also involves multi-objective programming method and two-stage/multistage stochastic programming methods. In particular for the long-term sequential planning under uncertainties, to reduce the computational challenges due to the exponential expansion of the scenario tree, I also developed efficient ND-Max method which is more efficient than CPLEX and Nested Decomposition method. Through result analysis of four independent studies, it is found that the proposed modeling frameworks can effectively improve the economic performance, enhance environmental benefits and reduce risks due to systems uncertainties for the biofuel supply chain systems.

  1. Optimal ventilation of the anesthetized pediatric patient.

    PubMed

    Feldman, Jeffrey M

    2015-01-01

    Mechanical ventilation of the pediatric patient is challenging because small changes in delivered volume can be a significant fraction of the intended tidal volume. Anesthesia ventilators have traditionally been poorly suited to delivering small tidal volumes accurately, and pressure-controlled ventilation has become used commonly when caring for pediatric patients. Modern anesthesia ventilators are designed to deliver small volumes accurately to the patient's airway by compensating for the compliance of the breathing system and delivering tidal volume independent of fresh gas flow. These technology advances provide the opportunity to implement a lung-protective ventilation strategy in the operating room based upon control of tidal volume. This review will describe the capabilities of the modern anesthesia ventilator and the current understanding of lung-protective ventilation. An optimal approach to mechanical ventilation for the pediatric patient is described, emphasizing the importance of using bedside monitors to optimize the ventilation strategy for the individual patient.

  2. [Assessment of the air quality improment of cleaning and disinfection on central air-conditioning ventilation system].

    PubMed

    Liu, Hongliang; Zhang, Lei; Feng, Lihong; Wang, Fei; Xue, Zhiming

    2009-09-01

    To assess the effect of air quality of cleaning and disinfection on central air-conditioning ventilation systems. 102 air-conditioning ventilation systems in 46 public facilities were sampled and investigated based on Hygienic assessment criterion of cleaning and disinfection of public central air-conditioning systems. Median dust volume decreased from 41.8 g/m2 to 0.4 g/m2, and the percentage of pipes meeting the national standard for dust decreased from 17.3% (13/60) to 100% (62/62). In the dust, median aerobic bacterial count decreased from 14 cfu/cm2 to 1 cfu/cm2. Median aerobic fungus count decreased from 10 cfu/cm2 to 0 cfu/cm2. The percentage of pipes with bacterial and fungus counts meeting the national standard increased from 92.4% (171/185) and 82.2% (152/185) to 99.4% (165/166) and 100% (166/166), respectively. In the ventilation air, median aerobic bacterial count decreased from 756 cfu/m3 to 229 cfu/m3. Median aerobic fungus count decreased from 382 cfu/m3 to 120 cfu/m3. The percentage of pipes meeting the national standard for ventilation air increased from 33.3% (81/243) and 62.1% (151/243) to 79.8% (292/366) and 87.7% (242/276), respectively. But PM10 rose from 0.060 mg/m3 to 0.068 mg/m3, and the percentage of pipes meeting the national standard for PM10 increased from 74.2% (13/60) to 90.2% (46/51). The cleaning and disinfection of central air-conditioning ventilation systems could have a beneficial effect of air quality.

  3. 46 CFR 111.106-15 - Ventilation of hazardous locations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... its operational controls outside the ventilated space, if the system is mechanical; and (3) Have a... opening. (c) The mechanical ventilation of enclosed flammable or combustible liquid cargo handling or.... The power ventilation system must be designed to remove vapors from the bottom of the space at points...

  4. [Disinfectants and main sanitary and preventive measures for protection of ventilation and air-conditioning systems from Legionella contamination].

    PubMed

    Gerasimov, V N; Golov, E A; Khramov, M V; Diatlov, I A

    2008-01-01

    The study was devoted to selection and assessment of disinfecting preparations for prevention of contamination by Legionella. Using system of criteria for quality assessment of disinfectants, seven newdomestic ones belonging to quaternary ammonium compounds class or to oxygen-containing preparations and designed for disinfecting of air-conditioning and ventilation systems were selected. Antibacterial and disinfecting activities of working solutions of disinfectants were tested in laboratory on the test-surfaces and test-objects of premises' air-conditioning and ventilation systems contaminated with Legionella. High antimicrobial and disinfecting activity of new preparations "Dezactiv-M", "ExtraDez", "Emital-Garant", "Aquasept Plus", "Samarovka", "Freesept", and "Ecobreeze Oxy" during their exposure on objects and materials contaminated with Legionella was shown. Main sanitary and preventive measures for defending of air-conditioning and ventilation systems from contamination by Legionella species were presented.

  5. Design and calibration of a high-frequency oscillatory ventilator.

    PubMed

    Simon, B A; Mitzner, W

    1991-02-01

    High-frequency ventilation (HFV) is a modality of mechanical ventilation which presents difficult technical demands to the clinical or laboratory investigator. The essential features of an ideal HFV system are described, including wide frequency range, control of tidal volume and mean airway pressure, minimal dead space, and high effective internal impedance. The design and performance of a high-frequency oscillatory ventilation system is described which approaches these requirements. The ventilator utilizes a linear motor regulated by a closed loop controller and driving a novel frictionless double-diaphragm piston pump. Finally, the ventilator performance is tested using the impedance model of Venegas [1].

  6. Ventilation of an hydrofoil wake

    NASA Astrophysics Data System (ADS)

    Arndt, Roger; Lee, Seung Jae; Monson, Garrett

    2013-11-01

    Ventilation physics plays a role in a variety of important engineering applications. For example, hydroturbine ventilation is used for control of vibration and cavitation erosion and more recently for improving the dissolved oxygen content of the flow through the turbine. The latter technology has been the focus of an ongoing study involving the ventilation of an hydrofoil wake to determine the velocity and size distribution of bubbles in a bubbly wake. This was carried out by utilizing particle shadow velocimetry (PSV). This technique is a non-scattering approach that relies on direct in-line volume illumination by a pulsed source such as a light-emitting diode (LED). The data are compared with previous studies of ventilated flow. The theoretical results of Hinze suggest that a scaling relationship is possible that can lead to developing appropriate design parameters for a ventilation system. Sponsored by ONR and DOE.

  7. Tunnel Ventilation Control Using Reinforcement Learning Methodology

    NASA Astrophysics Data System (ADS)

    Chu, Baeksuk; Kim, Dongnam; Hong, Daehie; Park, Jooyoung; Chung, Jin Taek; Kim, Tae-Hyung

    The main purpose of tunnel ventilation system is to maintain CO pollutant concentration and VI (visibility index) under an adequate level to provide drivers with comfortable and safe driving environment. Moreover, it is necessary to minimize power consumption used to operate ventilation system. To achieve the objectives, the control algorithm used in this research is reinforcement learning (RL) method. RL is a goal-directed learning of a mapping from situations to actions without relying on exemplary supervision or complete models of the environment. The goal of RL is to maximize a reward which is an evaluative feedback from the environment. In the process of constructing the reward of the tunnel ventilation system, two objectives listed above are included, that is, maintaining an adequate level of pollutants and minimizing power consumption. RL algorithm based on actor-critic architecture and gradient-following algorithm is adopted to the tunnel ventilation system. The simulations results performed with real data collected from existing tunnel ventilation system and real experimental verification are provided in this paper. It is confirmed that with the suggested controller, the pollutant level inside the tunnel was well maintained under allowable limit and the performance of energy consumption was improved compared to conventional control scheme.

  8. Natural ventilation systems to enhance sustainability in buildings: a review towards zero energy buildings in schools

    NASA Astrophysics Data System (ADS)

    Gil-Baez, Maite; Barrios-Padura, Ángela; Molina-Huelva, Marta; Chacartegui, Ricardo

    2017-11-01

    European regulations set the condition of Zero Energy Buildings for new buildings since 2020, with an intermediate milestone in 2018 for public buildings, in order to control greenhouse gases emissions control and climate change mitigation. Given that main fraction of energy consumption in buildings operation is due to HVAC systems, advances in its design and operation conditions are required. One key element for energy demand control is passive design of buildings. On this purpose, different recent studies and publications analyse natural ventilation systems potential to provide indoor air quality and comfort conditions minimizing electric power consumption. In these passive systems are of special relevance their capacities as passive cooling systems as well as air renovation systems, especially in high-density occupied spaces. With adequate designs, in warm/mild climates natural ventilation systems can be used along the whole year, maintaining indoor air quality and comfort conditions with small support of other heating/cooling systems. In this paper is analysed the state of the art of natural ventilation systems applied to high density occupied spaces with special focus on school buildings. The paper shows the potential and applicability of these systems for energy savings and discusses main criteria for their adequate integration in school building designs.

  9. Bacteriological evaluation of a down-draught necropsy table ventilation system.

    PubMed Central

    al-Wali, W; Kibbler, C C; McLaughlin, J E

    1993-01-01

    AIMS--To evaluate the microbiological efficacy of a down-draught necropsy table ventilation system (which surrounds the cadaver with a "curtain" of air under continuous extraction) during post mortem procedures. METHODS--Air sampling was carried out both in the presence and absence of staff and cadaver and during a full post mortem procedure, with functioning and non-functioning table air extraction. The penetration of the air "curtain" was also examined during the use of an oscillating bone saw by means of a tracer organism, Bacillus subtilis var niger, painted on to the skull. RESULTS--There was little difference between bacterial counts obtained in the presence of staff only, staff plus cadaver, or during a post mortem examination. With all counts obtained, however, there was a two to three-fold reduction when the ventilation was in operation compared with when the extract duct was occluded. Using the tracer organism, a two to three log reduction in counts was shown when the "curtain" was in operation during the use of the oscillating bone saw. CONCLUSIONS--These results suggest that the system provides potential protection for post mortem room staff against airborne infections. PMID:8408701

  10. Bacteriological evaluation of a down-draught necropsy table ventilation system.

    PubMed

    al-Wali, W; Kibbler, C C; McLaughlin, J E

    1993-08-01

    To evaluate the microbiological efficacy of a down-draught necropsy table ventilation system (which surrounds the cadaver with a "curtain" of air under continuous extraction) during post mortem procedures. Air sampling was carried out both in the presence and absence of staff and cadaver and during a full post mortem procedure, with functioning and non-functioning table air extraction. The penetration of the air "curtain" was also examined during the use of an oscillating bone saw by means of a tracer organism, Bacillus subtilis var niger, painted on to the skull. There was little difference between bacterial counts obtained in the presence of staff only, staff plus cadaver, or during a post mortem examination. With all counts obtained, however, there was a two to three-fold reduction when the ventilation was in operation compared with when the extract duct was occluded. Using the tracer organism, a two to three log reduction in counts was shown when the "curtain" was in operation during the use of the oscillating bone saw. These results suggest that the system provides potential protection for post mortem room staff against airborne infections.

  11. Initial mechanical ventilator settings and lung protective ventilation in the ED.

    PubMed

    Wilcox, Susan R; Richards, Jeremy B; Fisher, Daniel F; Sankoff, Jeffrey; Seigel, Todd A

    2016-08-01

    Mechanical ventilation with low tidal volumes has been shown to improve outcomes for patients both with and without acute respiratory distress syndrome. This study aims to characterize mechanically ventilated patients in the emergency department (ED), describe the initial ED ventilator settings, and assess for associations between lung protective ventilation strategies in the ED and outcomes. This was a multicenter, prospective, observational study of mechanical ventilation at 3 academic EDs. We defined lung protective ventilation as a tidal volume of less than or equal to 8 mL/kg of predicted body weight and compared outcomes for patients ventilated with lung protective vs non-lung protective ventilation, including inhospital mortality, ventilator days, intensive care unit length of stay, and hospital length of stay. Data from 433 patients were analyzed. Altered mental status without respiratory pathology was the most common reason for intubation, followed by trauma and respiratory failure. Two hundred sixty-one patients (60.3%) received lung protective ventilation, but most patients were ventilated with a low positive end-expiratory pressure, high fraction of inspired oxygen strategy. Patients were ventilated in the ED for a mean of 5 hours and 7 minutes but had few ventilator adjustments. Outcomes were not significantly different between patients receiving lung protective vs non-lung protective ventilation. Nearly 40% of ED patients were ventilated with non-lung protective ventilation as well as with low positive end-expiratory pressure and high fraction of inspired oxygen. Despite a mean ED ventilation time of more than 5 hours, few patients had adjustments made to their ventilators. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Hydronic rooftop cooling systems

    DOEpatents

    Bourne, Richard C [Davis, CA; Lee, Brian Eric [Monterey, CA; Berman, Mark J [Davis, CA

    2008-01-29

    A roof top cooling unit has an evaporative cooling section that includes at least one evaporative module that pre-cools ventilation air and water; a condenser; a water reservoir and pump that captures and re-circulates water within the evaporative modules; a fan that exhausts air from the building and the evaporative modules and systems that refill and drain the water reservoir. The cooling unit also has a refrigerant section that includes a compressor, an expansion device, evaporator and condenser heat exchangers, and connecting refrigerant piping. Supply air components include a blower, an air filter, a cooling and/or heating coil to condition air for supply to the building, and optional dampers that, in designs that supply less than 100% outdoor air to the building, control the mixture of return and ventilation air.

  13. 133Xe contamination found in internal bacteria filter of xenon ventilation system.

    PubMed

    Hackett, Michael T; Collins, Judith A; Wierzbinski, Rebecca S

    2003-09-01

    We report on (133)Xe contamination found in the reusable internal bacteria filter of our xenon ventilation system. Internal bacteria filters (n = 6) were evaluated after approximately 1 mo of normal use. The ventilation system was evacuated twice to eliminate (133)Xe in the system before removal of the filter. Upon removal, the filter was monitored using a survey meter with an energy-compensated probe and was imaged on a scintillation camera. The filter was monitored and imaged over several days and was stored in a fume hood. Estimated (133)Xe activity in each filter immediately after removal ranged from 132 to 2,035 kBq (3.6-55.0 micro Ci), based on imaging. Initial surface radiation levels ranged from 0.4 to 4.5 micro Sv/h (0.04-0.45 mrem/h). The (133)Xe activity did not readily leave the filter over time (i.e., time to reach half the counts of the initial decay-corrected image ranged from <6 to >72 h). The majority of the image counts (approximately 70%) were seen in 2 distinctive areas in the filter. They corresponded to sites where the manufacturer used polyurethane adhesive to attach the fiberglass filter medium to the filter housing. (133)Xe contamination within the reusable internal bacteria filter of our ventilation system was easily detected by a survey meter and imaging. Although initial activities and surface radiation levels were low, radiation safety practices would dictate that a (133)Xe-contaminated bacteria filter be stored preferably in a fume hood until it cannot be distinguished from background before autoclaving or disposal.

  14. New modes of assisted mechanical ventilation.

    PubMed

    Suarez-Sipmann, F

    2014-05-01

    Recent major advances in mechanical ventilation have resulted in new exciting modes of assisted ventilation. Compared to traditional ventilation modes such as assisted-controlled ventilation or pressure support ventilation, these new modes offer a number of physiological advantages derived from the improved patient control over the ventilator. By implementing advanced closed-loop control systems and using information on lung mechanics, respiratory muscle function and respiratory drive, these modes are specifically designed to improve patient-ventilator synchrony and reduce the work of breathing. Depending on their specific operational characteristics, these modes can assist spontaneous breathing efforts synchronically in time and magnitude, adapt to changing patient demands, implement automated weaning protocols, and introduce a more physiological variability in the breathing pattern. Clinicians have now the possibility to individualize and optimize ventilatory assistance during the complex transition from fully controlled to spontaneous assisted ventilation. The growing evidence of the physiological and clinical benefits of these new modes is favoring their progressive introduction into clinical practice. Future clinical trials should improve our understanding of these modes and help determine whether the claimed benefits result in better outcomes. Copyright © 2013 Elsevier España, S.L. and SEMICYUC. All rights reserved.

  15. End-expiratory lung volume and ventilation distribution with different continuous positive airway pressure systems in volunteers.

    PubMed

    Andersson, B; Lundin, S; Lindgren, S; Stenqvist, O; Odenstedt Hergès, H

    2011-02-01

    Continuous positive airway pressure (CPAP) has been shown to improve oxygenation and a number of different CPAP systems are available. The aim of this study was to assess lung volume and ventilation distribution using three different CPAP techniques. A high-flow CPAP system (HF-CPAP), an ejector-driven system (E-CPAP) and CPAP using a Servo 300 ventilator (V-CPAP) were randomly applied at 0, 5 and 10 cmH₂O in 14 volunteers. End-expiratory lung volume (EELV) was measured by N₂ dilution at baseline; changes in EELV and tidal volume distribution were assessed by electric impedance tomography. Higher end-expiratory and mean airway pressures were found using the E-CPAP vs. the HF-CPAP and the V-CPAP system (P<0.01). EELV increased markedly from baseline, 0 cmH₂O, with increased CPAP levels: 1110±380, 1620±520 and 1130±350 ml for HF-, E- and V-CPAP, respectively, at 10 cmH₂O. A larger fraction of the increase in EELV occurred for all systems in ventral compared with dorsal regions (P<0.01). In contrast, tidal ventilation was increasingly directed toward dorsal regions with increasing CPAP levels (P<0.01). The increase in EELV as well as the tidal volume redistribution were more pronounced with the E-CPAP system as compared with both the HF-CPAP and the V-CPAP systems (P<0.05) at 10 cmH₂O. EELV increased more in ventral regions with increasing CPAP levels, independent of systems, leading to a redistribution of tidal ventilation toward dorsal regions. Different CPAP systems resulted in different airway pressure profiles, which may result in different lung volume expansion and tidal volume distribution. © 2010 The Authors. Journal compilation © 2010 The Acta Anaesthesiologica Scandinavica Foundation.

  16. Development of an integrated medical supply information system

    NASA Astrophysics Data System (ADS)

    Xu, Eric; Wermus, Marek; Blythe Bauman, Deborah

    2011-08-01

    The integrated medical supply inventory control system introduced in this study is a hybrid system that is shaped by the nature of medical supply, usage and storage capacity limitations of health care facilities. The system links demand, service provided at the clinic, health care service provider's information, inventory storage data and decision support tools into an integrated information system. ABC analysis method, economic order quantity model, two-bin method and safety stock concept are applied as decision support models to tackle inventory management issues at health care facilities. In the decision support module, each medical item and storage location has been scrutinised to determine the best-fit inventory control policy. The pilot case study demonstrates that the integrated medical supply information system holds several advantages for inventory managers, since it entails benefits of deploying enterprise information systems to manage medical supply and better patient services.

  17. Daily Goals Formulation and Enhanced Visualization of Mechanical Ventilation Variance Improves Mechanical Ventilation Score.

    PubMed

    Walsh, Brian K; Smallwood, Craig; Rettig, Jordan; Kacmarek, Robert M; Thompson, John; Arnold, John H

    2017-03-01

    The systematic implementation of evidence-based practice through the use of guidelines, checklists, and protocols mitigates the risks associated with mechanical ventilation, yet variation in practice remains prevalent. Recent advances in software and hardware have allowed for the development and deployment of an enhanced visualization tool that identifies mechanical ventilation goal variance. Our aim was to assess the utility of daily goal establishment and a computer-aided visualization of variance. This study was composed of 3 phases: a retrospective observational phase (baseline) followed by 2 prospective sequential interventions. Phase I intervention comprised daily goal establishment of mechanical ventilation. Phase II intervention was the setting and monitoring of daily goals of mechanical ventilation with a web-based data visualization system (T3). A single score of mechanical ventilation was developed to evaluate the outcome. The baseline phase evaluated 130 subjects, phase I enrolled 31 subjects, and phase II enrolled 36 subjects. There were no differences in demographic characteristics between cohorts. A total of 171 verbalizations of goals of mechanical ventilation were completed in phase I. The use of T3 increased by 87% from phase I. Mechanical ventilation score improved by 8.4% in phase I and 11.3% in phase II from baseline ( P = .032). The largest effect was in the low risk V T category, with a 40.3% improvement from baseline in phase I, which was maintained at 39% improvement from baseline in phase II ( P = .01). mechanical ventilation score was 9% higher on average in those who survived. Daily goal formation and computer-enhanced visualization of mechanical ventilation variance were associated with an improvement in goal attainment by evidence of an improved mechanical ventilation score. Further research is needed to determine whether improvements in mechanical ventilation score through a targeted, process-oriented intervention will lead to

  18. [Lung protective ventilation. Ventilatory modes and ventilator parameters].

    PubMed

    Schädler, Dirk; Weiler, Norbert

    2008-06-01

    Mechanical ventilation has a considerable potential for injuring the lung tissue. Therefore, attention has to be paid to the proper choice of ventilatory mode and settings to secure lung-protective ventilation whenever possible. Such ventilator strategy should account for low tidal volume ventilation (6 ml/kg PBW), limited plateau pressure (30 to 35 cm H2O) and positive end-expiratory pressure (PEEP). It is unclear whether pressure controlled or volume controlled ventilation with square flow profile is beneficial. The adjustment of inspiration and expiration time should consider the actual breathing mechanics and anticipate the generation of intrinsic PEEP. Ventilatory modes with the possibility of supporting spontaneous breathing should be used as soon as possible.

  19. Variable mechanical ventilation

    PubMed Central

    Fontela, Paula Caitano; Prestes, Renata Bernardy; Forgiarini Jr., Luiz Alberto; Friedman, Gilberto

    2017-01-01

    Objective To review the literature on the use of variable mechanical ventilation and the main outcomes of this technique. Methods Search, selection, and analysis of all original articles on variable ventilation, without restriction on the period of publication and language, available in the electronic databases LILACS, MEDLINE®, and PubMed, by searching the terms "variable ventilation" OR "noisy ventilation" OR "biologically variable ventilation". Results A total of 36 studies were selected. Of these, 24 were original studies, including 21 experimental studies and three clinical studies. Conclusion Several experimental studies reported the beneficial effects of distinct variable ventilation strategies on lung function using different models of lung injury and healthy lungs. Variable ventilation seems to be a viable strategy for improving gas exchange and respiratory mechanics and preventing lung injury associated with mechanical ventilation. However, further clinical studies are necessary to assess the potential of variable ventilation strategies for the clinical improvement of patients undergoing mechanical ventilation. PMID:28444076

  20. Circuit compliance compensation in lung protective ventilation.

    PubMed

    Masselli, Grazia Maria Pia; Silvestri, Sergio; Sciuto, Salvatore Andrea; Cappa, Paolo

    2006-01-01

    Lung protective ventilation utilizes low tidal volumes to ventilate patients with severe lung pathologies. The compensation of breathing circuit effects, i.e. those induced by compressible volume of the circuit, results particularly critical in the calculation of the actual tidal volume delivered to patient's respiratory system which in turns is responsible of the level of permissive hypercapnia. The present work analyzes the applicability of the equation for circuit compressible volume compensation in the case of pressure and volume controlled lung protective ventilation. Experimental tests conducted in-vitro show that the actual tidal volume can be reliably estimated if the compliance of the breathing circuit is measured with the same parameters and ventilation technique that will be utilized in lung protective ventilation. Differences between volume and pressure controlled ventilation are also quantitatively assessed showing that pressure controlled ventilation allows a more reliable compensation of breathing circuit compressible volume.

  1. Mild hypothermia attenuates changes in respiratory system mechanics and modifies cytokine concentration in bronchoalveolar lavage fluid during low lung volume ventilation.

    PubMed

    Dostál, P; Senkeřík, M; Pařízková, R; Bareš, D; Zivný, P; Zivná, H; Cerný, V

    2010-01-01

    Hypothermia was shown to attenuate ventilator-induced lung injury due to large tidal volumes. It is unclear if the protective effect of hypothermia is maintained under less injurious mechanical ventilation in animals without previous lung injury. Tracheostomized rats were randomly allocated to non-ventilated group (group C) or ventilated groups of normothermia (group N) and mild hypothermia (group H). After two hours of mechanical ventilation with inspiratory fraction of oxygen 1.0, respiratory rate 60 min(-1), tidal volume 10 ml x kg(-1), positive end-expiratory pressure (PEEP) 2 cm H2O or immediately after tracheostomy in non-ventilated animals inspiratory pressures were recorded, rats were sacrificed, pressure-volume (PV) curve of respiratory system constructed, bronchoalveolar lavage (BAL) fluid and aortic blood samples obtained. Group N animals exhibited a higher rise in peak inspiratory pressures in comparison to group H animals. Shift of the PV curve to right, higher total protein and interleukin-6 levels in BAL fluid were observed in normothermia animals in comparison with hypothermia animals and non-ventilated controls. Tumor necrosis factor-alpha was lower in the hypothermia group in comparison with normothermia and non-ventilated groups. Mild hypothermia attenuated changes in respiratory system mechanics and modified cytokine concentration in bronchoalveolar lavage fluid during low lung volume ventilation in animals without previous lung injury.

  2. A novel fiber-optic measurement system for the evaluation of performances of neonatal pulmonary ventilators

    NASA Astrophysics Data System (ADS)

    Battista, L.; Scorza, A.; Botta, F.; Sciuto, S. A.

    2016-02-01

    Published standards for the performance evaluation of pulmonary ventilators are mainly directed to manufacturers rather than to end-users and often considered inadequate or not comprehensive. In order to contribute to overcome the problems above, a novel measurement system was proposed and tested with waveforms of mechanical ventilation by means of experimental trials carried out with infant ventilators typically used in neonatal intensive care units: the main quantities of mechanical ventilation in newborns are monitored, i.e. air flow rate, differential pressure and volume from infant ventilator are measured by means of two novel fiber-optic sensors (OFSs) developed and characterized by the authors, while temperature and relative humidity of air mass are obtained by two commercial transducers. The proposed fiber-optic sensors (flow sensor Q-OFS, pressure sensor P-OFS) showed measurement ranges of air flow and pressure typically encountered in neonatal mechanical ventilation, i.e. the air flow rate Q ranged from 3 l min-1 to 18 l min-1 (inspiratory) and from  -3 l min-1 to  -18 l min-1 (expiratory), the differential pressure ΔP ranged from  -15 cmH2O to 15 cmH2O. In each experimental trial carried out with different settings of the ventilator, outputs of the OFSs are compared with data from two reference sensors (reference flow sensor RF, reference pressure sensor RP) and results are found consistent: flow rate Q showed a maximum error between Q-OFS and RF up to 13 percent, with an output ratio Q RF/Q OFS of not more than 1.06  ±  0.09 (least square estimation, 95 percent confidence level, R 2 between 0.9822 and 0.9931). On the other hand the maximum error between P-OFS and RP on differential pressure ΔP was lower than 10 percent, with an output ratio ΔP RP/ΔP OFS between 0.977  ±  0.022 and 1.0  ±  0.8 (least square estimation, 95 percent confidence level, R 2 between 0.9864 and 0.9876). Despite the possible improvements

  3. The equine antitoxins supply system for biological poisons in Japan.

    PubMed

    Nakai, Kiyohito; Takahashi, Motohide; Tomita, Motowo

    2003-10-01

    Recently, the equine antitoxin supply in Japan has sharply decreased; then it is apparent that a stable supply produced solely by private industry cannot be relied upon. The Ministry of Health, Labor and Welfare (MHLW), therefore, purchases vaccines and equine antitoxins from manufacturers who could not otherwise independently provide an adequate antitoxin supply to hospitals. This supply system is called the 'Kokuyu vaccine system.' Under this system, MHLW purchases, stores and distributes vaccines and antitoxins to hospitals. This system has worked efficiently and effectively so far and may be a good model for establishing a stable antitoxin supply system in other countries.

  4. A ventilation intervention study in classrooms to improve indoor air quality: the FRESH study

    PubMed Central

    2013-01-01

    Background Classroom ventilation rates often do not meet building standards, although it is considered to be important to improve indoor air quality. Poor indoor air quality is thought to influence both children’s health and performance. Poor ventilation in The Netherlands most often occurs in the heating season. To improve classroom ventilation a tailor made mechanical ventilation device was developed to improve outdoor air supply. This paper studies the effect of this intervention. Methods The FRESH study (Forced-ventilation Related Environmental School Health) was designed to investigate the effect of a CO2 controlled mechanical ventilation intervention on classroom CO2 levels using a longitudinal cross-over design. Target CO2 concentrations were 800 and 1200 parts per million (ppm), respectively. The study included 18 classrooms from 17 schools from the north-eastern part of The Netherlands, 12 experimental classrooms and 6 control classrooms. Data on indoor levels of CO2, temperature and relative humidity were collected during three consecutive weeks per school during the heating seasons of 2010–2012. Associations between the intervention and weekly average indoor CO2 levels, classroom temperature and relative humidity were assessed by means of mixed models with random school-effects. Results At baseline, mean CO2 concentration for all schools was 1335 ppm (range: 763–2000 ppm). The intervention was able to significantly decrease CO2 levels in the intervention classrooms (F (2,10) = 17.59, p < 0.001), with a mean decrease of 491 ppm. With the target set at 800 ppm, mean CO2 was 841 ppm (range: 743–925 ppm); with the target set at 1200 ppm, mean CO2 was 975 ppm (range: 887–1077 ppm). Conclusions Although the device was not capable of precisely achieving the two predefined levels of CO2, our study showed that classroom CO2 levels can be reduced by intervening on classroom ventilation using a CO2 controlled mechanical ventilation system

  5. A ventilation intervention study in classrooms to improve indoor air quality: the FRESH study.

    PubMed

    Rosbach, Jeannette T M; Vonk, Machiel; Duijm, Frans; van Ginkel, Jan T; Gehring, Ulrike; Brunekreef, Bert

    2013-12-17

    Classroom ventilation rates often do not meet building standards, although it is considered to be important to improve indoor air quality. Poor indoor air quality is thought to influence both children's health and performance. Poor ventilation in The Netherlands most often occurs in the heating season. To improve classroom ventilation a tailor made mechanical ventilation device was developed to improve outdoor air supply. This paper studies the effect of this intervention. The FRESH study (Forced-ventilation Related Environmental School Health) was designed to investigate the effect of a CO2 controlled mechanical ventilation intervention on classroom CO2 levels using a longitudinal cross-over design. Target CO2 concentrations were 800 and 1200 parts per million (ppm), respectively. The study included 18 classrooms from 17 schools from the north-eastern part of The Netherlands, 12 experimental classrooms and 6 control classrooms. Data on indoor levels of CO2, temperature and relative humidity were collected during three consecutive weeks per school during the heating seasons of 2010-2012. Associations between the intervention and weekly average indoor CO2 levels, classroom temperature and relative humidity were assessed by means of mixed models with random school-effects. At baseline, mean CO2 concentration for all schools was 1335 ppm (range: 763-2000 ppm). The intervention was able to significantly decrease CO2 levels in the intervention classrooms (F (2,10) = 17.59, p < 0.001), with a mean decrease of 491 ppm. With the target set at 800 ppm, mean CO2 was 841 ppm (range: 743-925 ppm); with the target set at 1200 ppm, mean CO2 was 975 ppm (range: 887-1077 ppm). Although the device was not capable of precisely achieving the two predefined levels of CO2, our study showed that classroom CO2 levels can be reduced by intervening on classroom ventilation using a CO2 controlled mechanical ventilation system.

  6. The School Advanced Ventilation Engineering Software (SAVES)

    EPA Pesticide Factsheets

    The School Advanced Ventilation Engineering Software (SAVES) package is a tool to help school designers assess the potential financial payback and indoor humidity control benefits of Energy Recovery Ventilation (ERV) systems for school applications.

  7. Night ventilation control strategies in office buildings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Zhaojun; Yi, Lingli; Gao, Fusheng

    2009-10-15

    In moderate climates night ventilation is an effective and energy-efficient approach to improve the indoor thermal environment for office buildings during the summer months, especially for heavyweight construction. However, is night ventilation a suitable strategy for office buildings with lightweight construction located in cold climates? In order to answer this question, the whole energy-consumption analysis software EnergyPlus was used to simulate the indoor thermal environment and energy consumption in typical office buildings with night mechanical ventilation in three cities in northern China. The summer outdoor climate data was analyzed, and three typical design days were chosen. The most important factorsmore » influencing night ventilation performance such as ventilation rates, ventilation duration, building mass and climatic conditions were evaluated. When night ventilation operation time is closer to active cooling time, the efficiency of night ventilation is higher. With night ventilation rate of 10 ach, the mean radiant temperature of the indoor surface decreased by up to 3.9 C. The longer the duration of operation, the more efficient the night ventilation strategy becomes. The control strategies for three locations are given in the paper. Based on the optimized strategies, the operation consumption and fees are calculated. The results show that more energy is saved in office buildings cooled by a night ventilation system in northern China than ones that do not employ this strategy. (author)« less

  8. 46 CFR 58.01-45 - Machinery space, ventilation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Machinery space, ventilation. 58.01-45 Section 58.01-45... MACHINERY AND RELATED SYSTEMS General Requirements § 58.01-45 Machinery space, ventilation. Each machinery space must be ventilated to ensure that, when machinery or boilers are operating at full power in all...

  9. 46 CFR 58.01-45 - Machinery space, ventilation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Machinery space, ventilation. 58.01-45 Section 58.01-45... MACHINERY AND RELATED SYSTEMS General Requirements § 58.01-45 Machinery space, ventilation. Each machinery space must be ventilated to ensure that, when machinery or boilers are operating at full power in all...

  10. 46 CFR 58.01-45 - Machinery space, ventilation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Machinery space, ventilation. 58.01-45 Section 58.01-45... MACHINERY AND RELATED SYSTEMS General Requirements § 58.01-45 Machinery space, ventilation. Each machinery space must be ventilated to ensure that, when machinery or boilers are operating at full power in all...

  11. 46 CFR 58.01-45 - Machinery space, ventilation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Machinery space, ventilation. 58.01-45 Section 58.01-45... MACHINERY AND RELATED SYSTEMS General Requirements § 58.01-45 Machinery space, ventilation. Each machinery space must be ventilated to ensure that, when machinery or boilers are operating at full power in all...

  12. 46 CFR 58.01-45 - Machinery space, ventilation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Machinery space, ventilation. 58.01-45 Section 58.01-45... MACHINERY AND RELATED SYSTEMS General Requirements § 58.01-45 Machinery space, ventilation. Each machinery space must be ventilated to ensure that, when machinery or boilers are operating at full power in all...

  13. Strategic supply system design - a holistic evaluation of operational and production cost for a biorefinery supply chain

    DOE PAGES

    Lamers, Patrick; Tan, Eric C. D.; Searcy, Erin M.; ...

    2015-08-20

    Here, pioneer cellulosic biorefineries across the United States rely on a conventional feedstock supply system based on one-year contracts with local growers, who harvest, locally store, and deliver feed-stock in low-density format to the conversion facility. While the conventional system is designed for high biomass yield areas, pilot scale operations have experienced feedstock supply shortages and price volatilities due to reduced harvests and competition from other industries. Regional supply dependency and the inability to actively manage feedstock stability and quality, provide operational risks to the biorefinery, which translate into higher investment risk. The advanced feedstock supply system based on amore » network of depots can mitigate many of these risks and enable wider supply system benefits. This paper compares the two concepts from a system-level perspective beyond mere logistic costs. It shows that while processing operations at the depot increase feedstock supply costs initially, they enable wider system benefits including supply risk reduction (leading to lower interest rates on loans), industry scale-up, conversion yield improvements, and reduced handling equipment and storage costs at the biorefinery. When translating these benefits into cost reductions per liter of gasoline equivalent (LGE), we find that total cost reductions between -0.46 to -0.21 per LGE for biochemical and -0.32 to -0.12 per LGE for thermochemical conversion pathways are possible. Naturally, these system level benefits will differ between individual actors along the feedstock supply chain. Further research is required with respect to depot sizing, location, and ownership structures.« less

  14. Strategic supply system design - a holistic evaluation of operational and production cost for a biorefinery supply chain

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lamers, Patrick; Tan, Eric C. D.; Searcy, Erin M.

    Here, pioneer cellulosic biorefineries across the United States rely on a conventional feedstock supply system based on one-year contracts with local growers, who harvest, locally store, and deliver feed-stock in low-density format to the conversion facility. While the conventional system is designed for high biomass yield areas, pilot scale operations have experienced feedstock supply shortages and price volatilities due to reduced harvests and competition from other industries. Regional supply dependency and the inability to actively manage feedstock stability and quality, provide operational risks to the biorefinery, which translate into higher investment risk. The advanced feedstock supply system based on amore » network of depots can mitigate many of these risks and enable wider supply system benefits. This paper compares the two concepts from a system-level perspective beyond mere logistic costs. It shows that while processing operations at the depot increase feedstock supply costs initially, they enable wider system benefits including supply risk reduction (leading to lower interest rates on loans), industry scale-up, conversion yield improvements, and reduced handling equipment and storage costs at the biorefinery. When translating these benefits into cost reductions per liter of gasoline equivalent (LGE), we find that total cost reductions between -0.46 to -0.21 per LGE for biochemical and -0.32 to -0.12 per LGE for thermochemical conversion pathways are possible. Naturally, these system level benefits will differ between individual actors along the feedstock supply chain. Further research is required with respect to depot sizing, location, and ownership structures.« less

  15. Solar chimney for natural ventilation: A review

    NASA Astrophysics Data System (ADS)

    Dhrubo, Abir Ahsan; Alam, Chowdhury Sadid; Rahman, Md. Mustafizur; Islam, A. K. M. Sadrul

    2017-06-01

    In the 21st century the talk of the time has been proper use of renewable energy sources due to the continuous depletion of non-renewable energy sources and global warming as a result of combustion of fossil fuels. The energy situation in the 3rd world countries is even worse. The continuous industrial development in the 1st world countries is hugely responsible for global temperature increase and greenhouse gas (GHG) emissions which badly affect the countries like Bangladesh. As of April 2016, the electricity generation capacity of Bangladesh was 12,399 MW to which only 60% of the total population have access to. The shortage of electricity during the summer season makes life very difficult. Cooling of buildings requires a large quantity of energy in the summer. An alternative cooling system can reduce the dependency on electricity. This paper specially deals with a passive cooling system that reduces pressure on the electricity supply and focuses on renewable energy sources. Here a different process engineering has been discussed which incorporates Earth-to-Air Heat Exchangers with solar collector enhanced solar chimney system. In this study natural ventilation of buildings, using solar chimney system is reviewed extensively. Experimentally it has already been observed that sufficient temperature drop takes place 2-3 m within the undisturbed ground, which can work as a heat sink for ambient air if passed through and can lead to attaining comfort zone at a confined location. During peak hours of summer this kind of system may work as a very efficient cooling system and reduces extra load on electricity supply.

  16. Adaptive support ventilation: State of the art review

    PubMed Central

    Fernández, Jaime; Miguelena, Dayra; Mulett, Hernando; Godoy, Javier; Martinón-Torres, Federico

    2013-01-01

    Mechanical ventilation is one of the most commonly applied interventions in intensive care units. Despite its life-saving role, it can be a risky procedure for the patient if not applied appropriately. To decrease risks, new ventilator modes continue to be developed in an attempt to improve patient outcomes. Advances in ventilator modes include closed-loop systems that facilitate ventilator manipulation of variables based on measured respiratory parameters. Adaptive support ventilation (ASV) is a positive pressure mode of mechanical ventilation that is closed-loop controlled, and automatically adjust based on the patient's requirements. In order to deliver safe and appropriate patient care, clinicians need to achieve a thorough understanding of this mode, including its effects on underlying respiratory mechanics. This article will discuss ASV while emphasizing appropriate ventilator settings, their advantages and disadvantages, their particular effects on oxygenation and ventilation, and the monitoring priorities for clinicians. PMID:23833471

  17. A Novel In-Line Delivery System to Administer Dry Powder Mannitol to Mechanically Ventilated Patients.

    PubMed

    Feng, Benny; Tang, Patricia; Leung, Sharon Shui Yee; Dhanani, Jayesh; Chan, Hak-Kim

    2017-04-01

    Mechanically ventilated patients commonly suffer from ventilator-associated pneumonia, hypoxemia, and other lower respiratory tract infection as a result of pathogen colonization and poor sputum clearance. Consequently, there is a high rate of morbidity and mortality in these patients. Dry powder mannitol increases sputum clearance, and therefore, we developed a system to administer it to mechanically ventilated patients without disconnection from the ventilator. The inspiratory line from a ventilator was split by using a three-way valve into two parallel lines where one contains a humidifier for normal breathing cycle and the other line contains a dry powder inhaler (Osmohaler™). The inspiratory air went through the dry powder line and aerosolized the mannitol powder only when its administration to a patient is required. We determined the delivered dose and particle size distributions of emitted aerosols in vitro from 9.5 mm endotracheal and 7.5 mm tracheostomy tubes, with inspiratory airflow of 60, 70, and 80 L/min. This novel setup was able to deliver 24.6% ± 3.33% of the 160 mg loaded dose mannitol powder (4 × 40 mg capsules) and 26.7% ± 2.19% of the 320 mg dose (4 × 80 mg capsules) when the endotracheal tube was used. With the shorter tracheostomy tube, the delivery dose increased to 35.6% ± 3.01% and 39.5% ± 2.04% of the 160 and 320 mg doses, respectively. The volume median diameters of the aerosols were in the respirable range with the largest value being 5.17 ± 0.87 μm. This delivery system has been shown to consistently deliver a high respirable dose of mannitol powder. Since this setup does not require disconnection of patients from the ventilator, it is safer for hypoxemic patients and easier to be adapted in a real clinical use.

  18. Outcomes management of mechanically ventilated patients: utilizing informatics technology.

    PubMed

    Smith, K R

    1998-11-01

    This article examines an informatics system developed for outcomes management of the mechanically ventilated adult population, focusing on weaning the patient from mechanical ventilation. The link between medical informatics and outcomes management is discussed, along with the development of methods, tools, and data sets for outcomes management of the mechanically ventilated adult population at an acute care academic institution. Pros and cons of this system are identified, and specific areas for improvement of future health care outcomes medical informatics systems are discussed.

  19. Noninvasive ventilation.

    PubMed

    Rabatin, J T; Gay, P C

    1999-08-01

    Noninvasive ventilation refers to the delivery of assisted ventilatory support without the use of an endotracheal tube. Noninvasive positive pressure ventilation (NPPV) can be delivered by using a volume-controlled ventilator, a pressure-controlled ventilator, a bilevel positive airway pressure ventilator, or a continuous positive airway pressure device. During the past decade, there has been a resurgence in the use of noninvasive ventilation, fueled by advances in technology and clinical trials evaluating its use. Several manufacturers produce portable devices that are simple to operate. This review describes the equipment, techniques, and complications associated with NPPV and also the indications for both short-term and long-term applications. NPPV clearly represents an important addition to the techniques available to manage patients with respiratory failure. Future clinical trials evaluating its many clinical applications will help to define populations of patients most apt to benefit from this type of treatment.

  20. Effectiveness of a personalized ventilation system in reducing personal exposure against directly released simulated cough droplets.

    PubMed

    Pantelic, J; Tham, K W; Licina, D

    2015-12-01

    The inhalation intake fraction was used as an indicator to compare effects of desktop personalized ventilation and mixing ventilation on personal exposure to directly released simulated cough droplets. A cough machine was used to simulate cough release from the front, back, and side of a thermal manikin at distances between 1 and 4 m. Cough droplet concentration was measured with an aerosol spectrometer in the breathing zone of a thermal manikin. Particle image velocimetry was used to characterize the velocity field in the breathing zone. Desktop personalized ventilation substantially reduced the inhalation intake fraction compared to mixing ventilation for all investigated distances and orientations of the cough release. The results point out that the orientation between the cough source and the breathing zone of the exposed occupant is an important factor that substantially influences exposure. Exposure to cough droplets was reduced with increasing distance between cough source and exposed occupant. The results from this study show that an advanced air distribution system such as personalized ventilation reduces exposure to cough-released droplets better than commonly applied overhead mixing ventilation. This work can inform HVAC engineers about different aspects of air distribution systems’ performance and can serve as an aid in making critical design decisions. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  1. Regenerative Blower for EVA Suit Ventilation Fan

    NASA Technical Reports Server (NTRS)

    Izenson, Michael G.; Chen, Weibo; Paul, Heather L.

    2010-01-01

    Portable life support systems in future space suits will include a ventilation subsystem driven by a dedicated fan. This ventilation fan must meet challenging requirements for pressure rise, flow rate, efficiency, size, safety, and reliability. This paper describes research and development that showed the feasibility of a regenerative blower that is uniquely suited to meet these requirements. We proved feasibility through component tests, blower tests, and design analysis. Based on the requirements for the Constellation Space Suit Element (CSSE) Portable Life Support System (PLSS) ventilation fan, we designed the critical elements of the blower. We measured the effects of key design parameters on blower performance using separate effects tests, and used the results of these tests to design a regenerative blower that will meet the ventilation fan requirements. We assembled a proof-of-concept blower and measured its performance at sub-atmospheric pressures that simulate a PLSS ventilation loop environment. Head/flow performance and maximum efficiency point data were used to specify the design and operating conditions for the ventilation fan. We identified materials for the blower that will enhance safety for operation in a lunar environment, and produced a solid model that illustrates the final design. The proof-of-concept blower produced the flow rate and pressure rise needed for the CSSE ventilation subsystem while running at 5400 rpm, consuming only 9 W of electric power using a non-optimized, commercial motor and controller and inefficient bearings. Scaling the test results to a complete design shows that a lightweight, compact, reliable, and low power regenerative blower can meet the performance requirements for future space suit life support systems.

  2. Expert system for the design of heating, ventilating, and air-conditioning systems. Master's thesis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Camejo, P.J.

    1989-12-01

    Expert systems are computer programs that seek to mimic human reason. An expert system shelf, a software program commonly used for developing expert systems in a relatively short time, was used to develop a prototypical expert system for the design of heating, ventilating, and air-conditioning (HVAC) systems in buildings. Because HVAC design involves several related knowledge domains, developing an expert system for HVAC design requires the integration of several smaller expert systems known as knowledge bases. A menu program and several auxiliary programs for gathering data, completing calculations, printing project reports, and passing data between the knowledge bases are neededmore » and have been developed to join the separate knowledge bases into one simple-to-use program unit.« less

  3. Shuttle cryogenic supply system optimization study

    NASA Technical Reports Server (NTRS)

    1971-01-01

    Technical information on different cryogenic supply systems is presented for selecting representative designs. Parametric data and sensitivity studies, and an evaluation of related technology status are included. An integrated mathematical model for hardware program support was developed. The life support system, power generation, and propellant supply are considered. The major study conclusions are the following: Optimum integrated systems tend towards maximizing liquid storage. Vacuum jacketing of tanks is a major effect on integrated systems. Subcritical storage advantages over supercritical storage decrease as the quantity of propellant or reactant decreases. Shuttle duty cycles are not severe. The operational mode has a significant effect on reliability. Components are available for most subsystem applications. Subsystems and components require a minimum amount of technology development.

  4. [Formaldehyde-reducing efficiency of a newly developed dissection-table-connected local ventilation system in the gross anatomy laboratory room].

    PubMed

    Shinoda, Koh; Oba, Jun

    2010-03-01

    In compliance with health and safety management guidelines against harmful formaldehyde (FA) levels in the gross anatomy laboratory, we newly developed a dissection-table-connected local ventilation system in 2006. The system was composed of (1) a simple plenum-chambered dissection table with low-cost filters, (2) a transparent vinyl flexible duct for easy mounting and removal, which connects the table and the exhaust pipe laid above the ceiling, and (3) an intake creating a downward-flow of air, which was installed on the ceiling just above each table. The dissection table was also designed as a separate-component system, of which the upper plate and marginal suction inlets can be taken apart for cleaning after dissection, and equipped with opening/closing side-windows for picking up materials dropped during dissection and a container underneath the table to receive exudate from the cadaver through a waste-fluid pipe. The local ventilation system dramatically reduced FA levels to 0.01-0.03 ppm in the gross anatomy laboratory room, resulting in no discomforting FA smell and irritating sensation while preserving the student's view of room and line of flow as well as solving the problems of high maintenance cost, sanitation issues inside the table, and working-inconvenience during dissection practice. Switching ventilation methods or power-modes, the current local ventilation system was demonstrated to be more than ten times efficient in FA reduction compared to the whole-room ventilation system and suggested that 11 m3/min/table in exhaust volume should decrease FA levels in both A- and B-measurements to less than 0.1 ppm in 1000 m3 space containing thirty-one 3.5%-FA-fixed cadavers.

  5. The ventilation problem in schools: literature review

    DOE PAGES

    Fisk, W. J.

    2017-07-06

    Based on a review of literature published in refereed archival journals, ventilation rates in classrooms often fall far short of the minimum ventilation rates specified in standards. We report that there is compelling evidence, from both cross-sectional and intervention studies, of an association of increased student performance with increased ventilation rates. There is evidence that reduced respiratory health effects and reduced student absence are associated with increased ventilation rates. Increasing ventilation rates in schools imposes energy costs and can increase heating, ventilating, and air-conditioning system capital costs. The net annual costs, ranging from a few dollars to about 10 dollarsmore » per person, are less than 0.1% of typical public spending on elementary and secondary education in the United States. Finally, such expenditures seem like a small price to pay given the evidence of health and performance benefits.« less

  6. The ventilation problem in schools: literature review

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fisk, W. J.

    Based on a review of literature published in refereed archival journals, ventilation rates in classrooms often fall far short of the minimum ventilation rates specified in standards. We report that there is compelling evidence, from both cross-sectional and intervention studies, of an association of increased student performance with increased ventilation rates. There is evidence that reduced respiratory health effects and reduced student absence are associated with increased ventilation rates. Increasing ventilation rates in schools imposes energy costs and can increase heating, ventilating, and air-conditioning system capital costs. The net annual costs, ranging from a few dollars to about 10 dollarsmore » per person, are less than 0.1% of typical public spending on elementary and secondary education in the United States. Finally, such expenditures seem like a small price to pay given the evidence of health and performance benefits.« less

  7. New control design principles based on measured performance and energy analysis of HVAC (Heating, Ventilating, and Air-Conditioning) systems

    NASA Astrophysics Data System (ADS)

    Hittle, D. C.; Johnson, D. L.

    1985-01-01

    This report is one of a series on the development of heating, ventilating, and air-conditioning (HVAC) control systems that are simple, efficient, reliable, maintainable, and well-documented. This report identifies major problems associated with three currently used HVAC control systems. It also describes the development of a retrofit control system applicable to military buildings that will allow easy identification of component failures, facilitate repair, and minimize system failures. Evaluation of currently used controls showed that pneumatic temperature control equipment requires a very clean source of supply air and is also not very accurate. Pneumatic, rather than electronic, actuators should be used because they are cheaper and require less maintenance. Thermistor temperature detectors should not be used for HVAC applications because they require frequent calibration. It was found that enthalpy economy cycles cannot be used for control because the humidity sensors required for their use are prone to rapid drift, inaccurate, and hard to calibrate in the field. Performance of control systems greatly affects HVAC operating costs. Significant savings can be achieved if proportional-plus-integral control schemes are used. Use of the retrofit prototype control panel developed in this study on variable-air-volume systems should provide significant energy cost savings, improve comfort and reliability, and reduce maintenance costs.

  8. TH-E-BRF-02: 4D-CT Ventilation Image-Based IMRT Plans Are Dosimetrically Comparable to SPECT Ventilation Image-Based Plans

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kida, S; University of Tokyo Hospital, Bunkyo, Tokyo; Bal, M

    image-based plans, providing evidence to use 4D-CT ventilation imaging for clinical applications. Supported in part by Free to Breathe Young Investigator Research Grant and NIH/NCI R01 CA 093626. The authors thank Philips Radiation Oncology Systems for the Pinnacle3 treatment planning systems.« less

  9. Ventilation and infiltration in high-rise apartment buildings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Diamond, R.C.; Feustel, H.E.; Dickerhoff, D.J.

    1996-03-01

    Air flow, air leakage measurements and numerical simulations were made on a 13-story apartment building to characterize the ventilation rates for the individual apartments. Parametric simulations were performed for specific conditions, e.g., height, orientation, outside temperature and wind speed. Our analysis of the air flow simulations suggest that the ventilation to the individual units varies considerably. With the mechanical ventilation system disabled and no wind, units at the lower level of the building have adequate ventilation only on days with high temperature differences, while units on higher floors have no ventilation at all. Units facing the windward side will bemore » over-ventilated when the building experiences wind directions between west and north. At the same time, leeward apartments did not experience any fresh air-because, in these cases, air flows enter the apartments from the corridor and exit through the exhaust shafts and the cracks in the facade. Even with the mechanical ventilation system operating, we found wide variation in the air flows to the individual apartments. In addition to the specific case presented here, these findings have more general implications for energy retrofits and health and comfort of occupants in high-rise apartment buildings.« less

  10. Prospects for development of heat supply systems in high-rise districts

    NASA Astrophysics Data System (ADS)

    Zhila, Viktor; Solovyeva, Elena

    2018-03-01

    The article analyzes the main advantages and disadvantages of centralized and decentralized heat supply systems in high-rise districts. The main schemes of centralized heat supply systems are considered. They include centralized heat supply from boiler houses, centralized heat supply from autonomous heat sources, heat supply from roof boiler houses and door-to-door heating supply. For each of these variant, the gas distribution systems are considered and analyzed. These systems vary depending on the heat source location. For each of these systems, technical and economic indicators are taken into account, the analysis of which allows choosing the best option for districts where high-rise buildings predominate.

  11. Short-term airing by natural ventilation - modeling and control strategies.

    PubMed

    Perino, M; Heiselberg, P

    2009-10-01

    The need to improve the energy efficiency of buildings requires new and more efficient ventilation systems. It has been demonstrated that innovative operating concepts that make use of natural ventilation seem to be more appreciated by occupants. This kind of system frequently integrates traditional mechanical ventilation components with natural ventilation devices, such as motorized windows and louvers. Among the various ventilation strategies that are currently available, buoyancy driven single-sided natural ventilation has proved to be very effective and can provide high air change rates for temperature and IAQ control. However, in order to promote a wider applications of these systems, an improvement in the knowledge of their working principles and the availability of new design and simulation tools is necessary. In this context, the paper analyses and presents the results of a research that was aimed at developing and validating numerical models for the analysis of buoyancy driven single-sided natural ventilation systems. Once validated, these models can be used to optimize control strategies in order to achieve satisfactory indoor comfort conditions and IAQ. Practical Implications Numerical and experimental analyses have proved that short-term airing by intermittent ventilation is an effective measure to satisfactorily control IAQ. Different control strategies have been investigated to optimize the capabilities of the systems. The proposed zonal model has provided good performances and could be adopted as a design tool, while CFD simulations can be profitably used for detailed studies of the pollutant concentration distribution in a room and to address local discomfort problems.

  12. Knowledge management system for risk mitigation in supply chain uncertainty: case from automotive battery supply chain

    NASA Astrophysics Data System (ADS)

    Marie, I. A.; Sugiarto, D.; Surjasa, D.; Witonohadi, A.

    2018-01-01

    Automotive battery supply chain include battery manufacturer, sulphuric acid suppliers, polypropylene suppliers, lead suppliers, transportation service providers, warehouses, retailers and even customers. Due to the increasingly dynamic condition of the environment, supply chain actors were required to improve their ability to overcome various uncertainty issues in the environment. This paper aims to describe the process of designing a knowledge management system for risk mitigation in supply chain uncertainty. The design methodology began with the identification of the knowledge needed to solve the problems associated with uncertainty and analysis of system requirements. The design of the knowledge management system was described in the form of a data flow diagram. The results of the study indicated that key knowledge area that needs to be managed were the knowledge to maintain the stability of process in sulphuric acid process and knowledge to overcome the wastes in battery manufacturing process. The system was expected to be a media acquisition, dissemination and storage of knowledge associated with the uncertainty in the battery supply chain and increase the supply chain performance.

  13. Ventilation of carbon monoxide from a biomass pellet storage tank--a study of the effects of variation of temperature and cross-ventilation on the efficiency of natural ventilation.

    PubMed

    Emhofer, Waltraud; Lichtenegger, Klaus; Haslinger, Walter; Hofbauer, Hermann; Schmutzer-Roseneder, Irene; Aigenbauer, Stefan; Lienhard, Martin

    2015-01-01

    Wood pellets have been reported to emit toxic gaseous emissions during transport and storage. Carbon monoxide (CO) emission, due to the high toxicity of the gas and the possibility of it being present at high levels, is the most imminent threat to be considered before entering a pellet storage facility. For small-scale (<30 tons storage capacity) residential pellet storage facilities, ventilation, preferably natural ventilation utilizing already existing openings, has become the most favored solution to overcome the problem of high CO concentrations. However, there is little knowledge on the ventilation rates that can be reached and thus on the effectiveness of such measures. The aim of the study was to investigate ventilation rates for a specific small-scale pellet storage system depending on characteristic temperature differences. Furthermore, the influence of the implementation of a chimney and the influence of cross-ventilation on the ventilation rates were investigated. The air exchange rates observed in the experiments ranged between close to zero and up to 8 m(3) h(-1), depending largely on the existing temperature differences and the existence of cross-ventilation. The results demonstrate that implementing natural ventilation is a possible measure to enhance safety from CO emissions, but not one without limitations. © The Author 2014. Published by Oxford University Press on behalf of the British Occupational Hygiene Society.

  14. Employing a Modified Diffuser Momentum Model to Simulate Ventilation of the Orion CEV (DRAFT)

    NASA Technical Reports Server (NTRS)

    Straus, John; Ball, Tyler; OHara, William; Barido, Richard

    2011-01-01

    Computational Fluid Dynamics (CFD) is used to model the flow field in the Orion CEV cabin. The CFD model employs a momentum model used to account for the effect of supply grilles on the supply flow. The momentum model is modified to account for non-uniform velocity profiles at the approach of the supply grille. The modified momentum model is validated against a detailed vane-resolved model before inclusion into the Orion CEV cabin model. Results for this comparison, as well as that of a single ventilation configuration are presented.

  15. GENERAL VIEW SHOWING VENTILATOR NUMBER NINE. THIS VENTILATOR IS SLIGHTLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL VIEW SHOWING VENTILATOR NUMBER NINE. THIS VENTILATOR IS SLIGHTLY MORE ORNATE THAN WAS GENERALLY USED BECAUSE OF ITS LOCATION - Old Croton Aqueduct, Ventilator Number 9, Spring & Everett Streets, Ossining, Westchester County, NY

  16. The Complex Economic System of Supply Chain Financing

    NASA Astrophysics Data System (ADS)

    Zhang, Lili; Yan, Guangle

    Supply Chain Financing (SCF) refers to a series of innovative and complicated financial services based on supply chain. The SCF set-up is a complex system, where the supply chain management and Small and Medium Enterprises (SMEs) financing services interpenetrate systematically. This paper establishes the organization structure of SCF System, and presents two financing models respectively, with or without the participation of the third-party logistic provider (3PL). Using Information Economics and Game Theory, the interrelationship among diverse economic sectors is analyzed, and the economic mechanism of development and existent for SCF system is demonstrated. New thoughts and approaches to solve SMEs financing problem are given.

  17. 1. GENERAL VIEW SHOWING VENTILATOR NO. 9. THIS VENTILATOR IS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. GENERAL VIEW SHOWING VENTILATOR NO. 9. THIS VENTILATOR IS SLIGHTLY MORE ORNATE THAN WAS GENERALLY USED BECAUSE OF ITS LOCATION. - Old Croton Aqueduct, Ventilator Number 9, Spring & Everett Streets, Ossining, Westchester County, NY

  18. Protective ventilation of preterm lambs exposed to acute chorioamnionitis does not reduce ventilation-induced lung or brain injury.

    PubMed

    Barton, Samantha K; Moss, Timothy J M; Hooper, Stuart B; Crossley, Kelly J; Gill, Andrew W; Kluckow, Martin; Zahra, Valerie; Wong, Flora Y; Pichler, Gerhard; Galinsky, Robert; Miller, Suzanne L; Tolcos, Mary; Polglase, Graeme R

    2014-01-01

    The onset of mechanical ventilation is a critical time for the initiation of cerebral white matter (WM) injury in preterm neonates, particularly if they are inadvertently exposed to high tidal volumes (VT) in the delivery room. Protective ventilation strategies at birth reduce ventilation-induced lung and brain inflammation and injury, however its efficacy in a compromised newborn is not known. Chorioamnionitis is a common antecedent of preterm birth, and increases the risk and severity of WM injury. We investigated the effects of high VT ventilation, after chorioamnionitis, on preterm lung and WM inflammation and injury, and whether a protective ventilation strategy could mitigate the response. Pregnant ewes (n = 18) received intra-amniotic lipopolysaccharide (LPS) 2 days before delivery, instrumentation and ventilation at 127±1 days gestation. Lambs were either immediately euthanased and used as unventilated controls (LPSUVC; n = 6), or were ventilated using an injurious high VT strategy (LPSINJ; n = 5) or a protective ventilation strategy (LPSPROT; n = 7) for a total of 90 min. Mean arterial pressure, heart rate and cerebral haemodynamics and oxygenation were measured continuously. Lungs and brains underwent molecular and histological assessment of inflammation and injury. LPSINJ lambs had poorer oxygenation than LPSPROT lambs. Ventilation requirements and cardiopulmonary and systemic haemodynamics were not different between ventilation strategies. Compared to unventilated lambs, LPSINJ and LPSPROT lambs had increases in pro-inflammatory cytokine expression within the lungs and brain, and increased astrogliosis (p<0.02) and cell death (p<0.05) in the WM, which were equivalent in magnitude between groups. Ventilation after acute chorioamnionitis, irrespective of strategy used, increases haemodynamic instability and lung and cerebral inflammation and injury. Mechanical ventilation is a potential contributor to WM injury in infants exposed to

  19. The imperative for stronger vaccine supply and logistics systems.

    PubMed

    Zaffran, Michel; Vandelaer, Jos; Kristensen, Debra; Melgaard, Bjørn; Yadav, Prashant; Antwi-Agyei, K O; Lasher, Heidi

    2013-04-18

    With the introduction of new vaccines, developing countries are facing serious challenges in their vaccine supply and logistics systems. Storage capacity bottlenecks occur at national, regional, and district levels and system inefficiencies threaten vaccine access, availability, and quality. As countries adopt newer and more expensive vaccines and attempt to reach people at different ages and in new settings, their logistics systems must be strengthened and optimized. As a first step, national governments, donors, and international agencies have crafted a global vision for 2020 vaccine supply and logistics systems with detailed plans of action to achieve five priority objectives. Vaccine products and packaging are designed to meet the needs of developing countries. Immunization supply systems support efficient and effective vaccine delivery. The environmental impact of energy, materials, and processes used in immunization systems is minimized. Immunization information systems enable better and more timely decision-making. Competent and motivated personnel are empowered to handle immunization supply chain issues. Over the next decade, vaccine supply and logistics systems in nearly all developing countries will require significant investments of time and resources from global and national partners, donors, and governments. These investments are critical if we are to reach more people with current and newer vaccines. Copyright © 2012 Elsevier Ltd. All rights reserved.

  20. Aerosol delivery with two ventilation modes during mechanical ventilation: a randomized study.

    PubMed

    Dugernier, Jonathan; Reychler, Gregory; Wittebole, Xavier; Roeseler, Jean; Depoortere, Virginie; Sottiaux, Thierry; Michotte, Jean-Bernard; Vanbever, Rita; Dugernier, Thierry; Goffette, Pierre; Docquier, Marie-Agnes; Raftopoulos, Christian; Hantson, Philippe; Jamar, François; Laterre, Pierre-François

    2016-12-01

    Volume-controlled ventilation has been suggested to optimize lung deposition during nebulization although promoting spontaneous ventilation is targeted to avoid ventilator-induced diaphragmatic dysfunction. Comparing topographic aerosol lung deposition during volume-controlled ventilation and spontaneous ventilation in pressure support has never been performed. The aim of this study was to compare lung deposition of a radiolabeled aerosol generated with a vibrating-mesh nebulizer during invasive mechanical ventilation, with two modes: pressure support ventilation and volume-controlled ventilation. Seventeen postoperative neurosurgery patients without pulmonary disease were randomly ventilated in pressure support or volume-controlled ventilation. Diethylenetriaminepentaacetic acid labeled with technetium-99m (2 mCi/3 mL) was administrated using a vibrating-mesh nebulizer (Aerogen Solo(®), provided by Aerogen Ltd, Galway, Ireland) connected to the endotracheal tube. Pulmonary and extrapulmonary particles deposition was analyzed using planar scintigraphy. Lung deposition was 10.5 ± 3.0 and 15.1 ± 5.0 % of the nominal dose during pressure support and volume-controlled ventilation, respectively (p < 0.05). Higher endotracheal tube and tracheal deposition was observed during pressure support ventilation (27.4 ± 6.6 vs. 20.7 ± 6.0 %, p < 0.05). A similar penetration index was observed for the right (p = 0.210) and the left lung (p = 0.211) with both ventilation modes. A high intersubject variability of lung deposition was observed with both modes regarding lung doses, aerosol penetration and distribution between the right and the left lung. In the specific conditions of the study, volume-controlled ventilation was associated with higher lung deposition of nebulized particles as compared to pressure support ventilation. The clinical benefit of this effect warrants further studies. Clinical trial registration NCT01879488.

  1. [Development of medical supplies management system].

    PubMed

    Zhong, Jianping; Shen, Beijun; Zhu, Huili

    2012-11-01

    This paper adopts advanced information technology to manage medical supplies, in order to improve the medical supplies management level and reduce material cost. It develops a Medical Supplies Management System with B/S and C/S mixed structure, optimizing material management process, building large equipment performance evaluation model, providing interface solution with HIS, and realizing real-time information briefing of high value material's consumption. The medical materials are managed during its full life-cycle. The material consumption of the clinical departments is monitored real-timely. Through the closed-loop management with pre-event budget, mid-event control and after-event analysis, it realizes the final purpose of management yielding benefit.

  2. Public Water-Supply Systems and Associated Water Use in Tennessee, 2000

    USGS Publications Warehouse

    Webbers, Ank

    2003-01-01

    Public water-supply systems in Tennessee provide water to meet customer needs for domestic, industrial, and commercial users and municipal services. In 2000, more than 500 public water-supply systems distributed about 890 million gallons per day (Mgal/d) of surface water and ground water to a population of about 5 million in Tennessee. Surface-water sources provided 64 percent (about 569 Mgal/d) of the State?s water supplies, primarily in Middle and East Tennessee. Ground water produced from wells and springs in Middle and East Tennessee and from wells in West Tennessee provided 36 percent (about 321 Mgal/d) of the public water supplies. Springs in Middle and East Tennessee provided about 14 percent (about 42 Mgal/d) of ground-water supplies used in the State. Per capita water use for Tennessee in 2000 was about 136 gallons per day. An additional 146 public water-supply systems provided approximately 84 Mgal/d of water supplies that were purchased from other water systems. Water withdrawals by public water-supply systems in Tennessee have increased by over 250 percent; from 250 Mgal/d in 1955 to 890 Mgal/d in 2000. Although Tennessee public water-supply systems withdraw less ground water than surface water, ground-water withdrawal rates reported by these systems continue to increase. In addition, the number of public water-supply systems reporting ground-water withdrawals of 1 Mgal/d or more in West Tennessee is increasing.

  3. Smart Power Supply for Battery-Powered Systems

    NASA Technical Reports Server (NTRS)

    Krasowski, Michael J.; Greer, Lawrence; Prokop, Norman F.; Flatico, Joseph M.

    2010-01-01

    A power supply for battery-powered systems has been designed with an embedded controller that is capable of monitoring and maintaining batteries, charging hardware, while maintaining output power. The power supply is primarily designed for rovers and other remote science and engineering vehicles, but it can be used in any battery alone, or battery and charging source applications. The supply can function autonomously, or can be connected to a host processor through a serial communications link. It can be programmed a priori or on the fly to return current and voltage readings to a host. It has two output power busses: a constant 24-V direct current nominal bus, and a programmable bus for output from approximately 24 up to approximately 50 V. The programmable bus voltage level, and its output power limit, can be changed on the fly as well. The power supply also offers options to reduce the programmable bus to 24 V when the set power limit is reached, limiting output power in the case of a system fault detected in the system. The smart power supply is based on an embedded 8051-type single-chip microcontroller. This choice was made in that a credible progression to flight (radiation hard, high reliability) can be assumed as many 8051 processors or gate arrays capable of accepting 8051-type core presently exist and will continue to do so for some time. To solve the problem of centralized control, this innovation moves an embedded microcontroller to the power supply and assigns it the task of overseeing the operation and charging of the power supply assets. This embedded processor is connected to the application central processor via a serial data link such that the central processor can request updates of various parameters within the supply, such as battery current, bus voltage, remaining power in battery estimations, etc. This supply has a direct connection to the battery bus for common (quiescent) power application. Because components from multiple vendors may have

  4. FLOW-i ventilator performance in the presence of a circle system leak.

    PubMed

    Lucangelo, Umberto; Ajčević, Miloš; Accardo, Agostino; Borelli, Massimo; Peratoner, Alberto; Comuzzi, Lucia; Zin, Walter A

    2017-04-01

    Recently, the FLOW-i anaesthesia ventilator was developed based on the SERVO-i intensive care ventilator. The aim of this study was to test the FLOW-i's tidal volume delivery in the presence of a leak in the breathing circuit. We ventilated a test lung model in volume-, pressure-, and pressure-regulated volume-controlled modes (VC, PC, and PRVC, respectively) with a FLOW-i. First, the circuit remained airtight and the ventilator was tested with fresh gas flows of 6, 1, and 0.3 L/min in VC, PC, and PRVC modes and facing 4 combinations of different resistive and elastic loads. Second, a fixed leak in the breathing circuit was introduced and the measurements repeated. In the airtight system, FLOW-i maintained tidal volume (VT) and circuit pressure at approximately the set values, independently of respiratory mode, load, or fresh gas flow. In the leaking circuit, set VT = 500 mL, FLOW-i delivered higher VTs in PC (about 460 mL) than in VC and PRVC, where VTs were substantially less than 500 mL. Interestingly, VT did not differ appreciably from 6 to 0.3 L/min of fresh air flow among the 3 ventilatory modes. In the absence of leakage, peak inspiratory pressures were similar, while they were 35-45 % smaller in PRVC and VC than in PC mode in the presence of leaks. In conclusion, FLOW-i maintained VT (down to fresh gas flows of 0.3 L/min) to 90 % of its preset value in PC mode, which was 4-5 times greater than in VC or PRVC modes.

  5. The respiratory system during resuscitation: a review of the history, risk of infection during assisted ventilation, respiratory mechanics, and ventilation strategies for patients with an unprotected airway.

    PubMed

    Wenzel, V; Idris, A H; Dörges, V; Nolan, J P; Parr, M J; Gabrielli, A; Stallinger, A; Lindner, K H; Baskett, P J

    2001-05-01

    The fear of acquiring infectious diseases has resulted in reluctance among healthcare professionals and the lay public to perform mouth-to-mouth ventilation. However, the benefit of basic life support for a patient in cardiopulmonary or respiratory arrest greatly outweighs the risk for secondary infection in the rescuer or the patient. The distribution of ventilation volume between lungs and stomach in the unprotected airway depends on patient variables such as lower oesophageal sphincter pressure, airway resistance and respiratory system compliance, and the technique applied while performing basic or advanced airway support, such as head position, inflation flow rate and time, which determine upper airway pressure. The combination of these variables determines gas distribution between the lungs and the oesophagus and subsequently, the stomach. During bag-valve-mask ventilation of patients in respiratory or cardiac arrest with oxygen supplementation (> or = 40% oxygen), a tidal volume of 6-7 ml kg(-1) ( approximately 500 ml) given over 1-2 s until the chest rises is recommended. For bag-valve-mask ventilation with room-air, a tidal volume of 10 ml kg(-1) (700-1000 ml) in an adult given over 2 s until the chest rises clearly is recommended. During mouth-to-mouth ventilation, a breath over 2 s sufficient to make the chest rise clearly (a tidal volume of approximately 10 ml kg(-1) approximately 700-1000 ml in an adult) is recommended.

  6. Intelligent vehicle electrical power supply system with central coordinated protection

    NASA Astrophysics Data System (ADS)

    Yang, Diange; Kong, Weiwei; Li, Bing; Lian, Xiaomin

    2016-07-01

    The current research of vehicle electrical power supply system mainly focuses on electric vehicles (EV) and hybrid electric vehicles (HEV). The vehicle electrical power supply system used in traditional fuel vehicles is rather simple and imperfect; electrical/electronic devices (EEDs) applied in vehicles are usually directly connected with the vehicle's battery. With increasing numbers of EEDs being applied in traditional fuel vehicles, vehicle electrical power supply systems should be optimized and improved so that they can work more safely and more effectively. In this paper, a new vehicle electrical power supply system for traditional fuel vehicles, which accounts for all electrical/electronic devices and complex work conditions, is proposed based on a smart electrical/electronic device (SEED) system. Working as an independent intelligent electrical power supply network, the proposed system is isolated from the electrical control module and communication network, and access to the vehicle system is made through a bus interface. This results in a clean controller power supply with no electromagnetic interference. A new practical battery state of charge (SoC) estimation method is also proposed to achieve more accurate SoC estimation for lead-acid batteries in traditional fuel vehicles so that the intelligent power system can monitor the status of the battery for an over-current state in each power channel. Optimized protection methods are also used to ensure power supply safety. Experiments and tests on a traditional fuel vehicle are performed, and the results reveal that the battery SoC is calculated quickly and sufficiently accurately for battery over-discharge protection. Over-current protection is achieved, and the entire vehicle's power utilization is optimized. For traditional fuel vehicles, the proposed vehicle electrical power supply system is comprehensive and has a unified system architecture, enhancing system reliability and security.

  7. RESIDENTIAL VENTILATION STUDY

    EPA Science Inventory

    This project evaluated the effectiveness, first costs and operational costs of various types of residential ventilation systems in three different climates in the U.S. The Agency, through its Energy Star Program, recommends that builders construct homes that are energy efficient ...

  8. Effect of heating-ventilation-air conditioning system sanitation on airborne fungal populations in residential environments.

    PubMed

    Garrison, R A; Robertson, L D; Koehn, R D; Wynn, S R

    1993-12-01

    Commercial air duct sanitation services are advertised to the public as being effective in reducing indoor aeroallergen levels despite the absence of published supporting data. Eight residential heat-ventilation-air conditioning (HVAC) systems in six homes and seven HVAC systems in five homes in winter and summer, respectively, were sampled to determine fungal colony forming units (CFUs) prior to and after an HVAC sanitation procedure was performed by a local company. Two houses in which no sanitation procedure was performed served as controls in each study phase. Two sample sets were obtained at each HVAC system prior to cleaning in order to determine baseline CFU levels. The test HVAC systems were then cleaned, and the HVAC systems allowed to operate as desired by the residents. Posttreatment sampling was performed 48 hours and then weekly after cleaning for 8 weeks. The HVAC systems were analyzed by exposing sterile 2% malt extract media plates at a 90-degree angle to the air flow at the air supply and air return vents. The baseline CFUs were similar in the control and study houses. Eight weeks after sanitation, the study houses demonstrated an overall CFU reduction of 92% during winter and 84% during summer. No reduction in CFU values was observed over the 8-week study period for the houses selected as controls. Further, HVAC sanitation appeared to reduce the number of fungal colonies entering and leaving the HVAC system, suggesting that the HVAC contained a significant percentage of the total fungal load in these homes. These data suggest that HVAC sanitation may be an effective tool in reducing airborne fungal populations in residential environments.

  9. Improvement of a Chemical Storage Room Ventilation System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yousif, Emad; Al-Dahhan, Wedad; Abed, Rashed Nema

    Scientists at universities across Iraq are actively working to report actual incidents and accidents occurring in their laboratories, as well as structural improvements made to improve safety and security, to raise awareness and encourage openness, leading to widespread adoption of robust Chemical Safety and Security (CSS) practices. This manuscript is the third in a series of five case studies describing laboratory incidents, accidents, and laboratory improvements. We summarize an improvement to the chemical storage room ventilation system at Al-Nahrain University to create and maintain a safe working atmosphere in an area where chemicals are stored and handled, using US andmore » European design practices, standards, and regulations.« less

  10. Comparison of exogenous surfactant therapy, mechanical ventilation with high end-expiratory pressure and partial liquid ventilation in a model of acute lung injury.

    PubMed

    Hartog, A; Vazquez de Anda, G F; Gommers, D; Kaisers, U; Verbrugge, S J; Schnabel, R; Lachmann, B

    1999-01-01

    We have compared three treatment strategies, that aim to prevent repetitive alveolar collapse, for their effect on gas exchange, lung mechanics, lung injury, protein transfer into the alveoli and surfactant system, in a model of acute lung injury. In adult rats, the lungs were ventilated mechanically with 100% oxygen and a PEEP of 6 cm H2O, and acute lung injury was induced by repeated lung lavage to obtain a PaO2 value < 13 kPa. Animals were then allocated randomly (n = 12 in each group) to receive exogenous surfactant therapy, ventilation with high PEEP (18 cm H2O), partial liquid ventilation or ventilation with low PEEP (8 cm H2O) (ventilated controls). Blood-gas values were measured hourly. At the end of the 4-h study, in six animals per group, pressure-volume curves were constructed and bronchoalveolar lavage (BAL) was performed, whereas in the remaining animals lung injury was assessed. In the ventilated control group, arterial oxygenation did not improve and protein concentration of BAL and conversion of active to non-active surfactant components increased significantly. In the three treatment groups, PaO2 increased rapidly to > 50 kPa and remained stable over the next 4 h. The protein concentration of BAL fluid increased significantly only in the partial liquid ventilation group. Conversion of active to non-active surfactant components increased significantly in the partial liquid ventilation group and in the group ventilated with high PEEP. In the surfactant group and partial liquid ventilation groups, less lung injury was found compared with the ventilated control group and the group ventilated with high PEEP. We conclude that although all three strategies improved PaO2 to > 50 kPa, the impact on protein transfer into the alveoli, surfactant system and lung injury differed markedly.

  11. Coal slurry fuel supply and purge system

    DOEpatents

    McDowell, Robert E.; Basic, Steven L.; Smith, Russel M.

    1994-01-01

    A coal slurry fuel supply and purge system for a locomotive engines is disclosed which includes a slurry recirculation path, a stand-by path for circulating slurry during idle or states of the engine when slurry fuel in not required by the engine, and an engine header fluid path connected to the stand-by path, for supplying and purging slurry fuel to and from fuel injectors. A controller controls the actuation of valves to facilitate supply and purge of slurry to and from the fuel injectors. A method for supplying and purging coal slurry in a compression ignition engine is disclosed which includes controlling fluid flow devices and valves in a plurality of fluid paths to facilitate continuous slurry recirculation and supply and purge of or slurry based on the operating state of the engine.

  12. Antibiotic therapy in ventilator-associated tracheobronchitis: a literature review.

    PubMed

    Alves, Abel Eduardo; Pereira, José Manuel

    2018-03-01

    The concept of ventilator-associated tracheobronchitis is controversial; its definition is not unanimously accepted and often overlaps with ventilator-associated pneumonia. Ventilator-associated tracheobronchitis has an incidence similar to that of ventilator-associated pneumonia, with a high prevalence of isolated multiresistant agents, resulting in an increase in the time of mechanical ventilation and hospitalization but without an impact on mortality. The performance of quantitative cultures may allow better diagnostic definition of tracheobronchitis associated with mechanical ventilation, possibly avoiding the overdiagnosis of this condition. One of the major difficulties in differentiating between ventilator-associated tracheobronchitis and ventilator-associated pneumonia is the exclusion of a pulmonary infiltrate by chest radiography; thoracic computed tomography, thoracic ultrasonography, or invasive specimen collection may also be required. The institution of systemic antibiotic therapy does not improve the clinical impact of ventilator-associated tracheobronchitis, particularly in reducing time of mechanical ventilation, hospitalization or mortality, despite the possible reduced progression to ventilator-associated pneumonia. However, there are doubts regarding the methodology used. Thus, considering the high prevalence of tracheobronchitis associated with mechanical ventilation, routine treatment of this condition would result in high antibiotic usage without clear benefits. However, we suggest the institution of antibiotic therapy in patients with tracheobronchitis associated with mechanical ventilation and septic shock and/or worsening of oxygenation, and other auxiliary diagnostic tests should be simultaneously performed to exclude ventilator-associated pneumonia. This review provides a better understanding of the differentiation between tracheobronchitis associated with mechanical ventilation and pneumonia associated with mechanical ventilation, which

  13. Implications of Natural Occlusion of Ventilated Racks on Ammonia and Sanitation Practices

    PubMed Central

    Creamer, Michelle A; Petty, Joann; Martin, Tara; Bergdall, Valerie; Hickman-Davis, Judy M

    2014-01-01

    Examination of ventilated rat racks prior to semiannual sanitation revealed silicone nozzles and ventilation ports that were partially or completely occluded with granular debris. We subsequently sought to document performance standards for rack sanitation and investigate the effect of ventilation port occlusion on rack function and animal husbandry practices. We hypothesized that individually ventilated cages with occluded airflow would require more frequent cage changes, comparable to those for static cages (that is, every 3 to 4 d). Sprague–Dawley rats were housed under one of 4 conditions: no airflow occlusion, occluded air-supply inlet, occluded air-exhaust outlet, and occlusion of both inlet and outlet. Cages were changed when daily ammonia concentration exceeded 20 ppm or after 14 d had elapsed. Most cages with unoccluded or partial airflow occlusion remained below the 20 ppm limit until day 12 or 13. Cages with occlusion of both inlet and outlet exceeded 20 ppm ammonia by as early as day 5. Airflow was significantly lower in cages with occlusion of both inlet and outlet airflow. Weekly inspection revealed that occlusion of ventilation ports was detectable by 3 mo after semiannual sanitation. This study demonstrates that silicone nozzles should be removed prior to rack sanitation to improve the effectiveness of cleaning ventilation ports and nozzles. While the rack is in use, silicone nozzles and ventilation ports should be inspected regularly to identify occlusion that is likely to diminish environmental quality in the cage. Intracage ammonia levels are significantly higher when both inlet and outlet airflow are occluded. PMID:24602544

  14. Implications of natural occlusion of ventilated racks on ammonia and sanitation practices.

    PubMed

    Creamer, Michelle A; Petty, Joann; Martin, Tara; Bergdall, Valerie; Hickman-Davis, Judy M

    2014-03-01

    Examination of ventilated rat racks prior to semiannual sanitation revealed silicone nozzles and ventilation ports that were partially or completely occluded with granular debris. We subsequently sought to document performance standards for rack sanitation and investigate the effect of ventilation port occlusion on rack function and animal husbandry practices. We hypothesized that individually ventilated cages with occluded airflow would require more frequent cage changes, comparable to those for static cages (that is, every 3 to 4 d). Sprague-Dawley rats were housed under one of 4 conditions: no airflow occlusion, occluded air-supply inlet, occluded air-exhaust outlet, and occlusion of both inlet and outlet. Cages were changed when daily ammonia concentration exceeded 20 ppm or after 14 d had elapsed. Most cages with unoccluded or partial airflow occlusion remained below the 20 ppm limit until day 12 or 13. Cages with occlusion of both inlet and outlet exceeded 20 ppm ammonia by as early as day 5. Airflow was significantly lower in cages with occlusion of both inlet and outlet airflow. Weekly inspection revealed that occlusion of ventilation ports was detectable by 3 mo after semiannual sanitation. This study demonstrates that silicone nozzles should be removed prior to rack sanitation to improve the effectiveness of cleaning ventilation ports and nozzles. While the rack is in use, silicone nozzles and ventilation ports should be inspected regularly to identify occlusion that is likely to diminish environmental quality in the cage. Intracage ammonia levels are significantly higher when both inlet and outlet airflow are occluded.

  15. [Pressure support ventilation and proportional assist ventilation during weaning from mechanical ventilation].

    PubMed

    Aguirre-Bermeo, H; Bottiroli, M; Italiano, S; Roche-Campo, F; Santos, J A; Alonso, M; Mancebo, J

    2014-01-01

    To compare tolerance, duration of mechanical ventilation (MV) and clinical outcomes during weaning from MV in patients subjected to either pressure support ventilation (PSV) or proportional assist ventilation (PAV). A prospective, observational study was carried out. Intensive Care Unit. A total of 40 consecutive subjects were allocated to either the PSV or the PAV group until each group contained 20 patients. Patients were included in the study when they met the criteria to begin weaning and the attending physician decided to initiate the weaning process. The physician selected the modality and set the ventilatory parameters. None. Demographic data, respiratory mechanics, ventilatory parameters, duration of MV, and clinical outcomes (reintubation, tracheostomy, mortality). Baseline characteristics were similar in both groups. No significant differences were observed between the PSV and PAV groups in terms of the total duration of MV (10 [5-18] vs. 9 [7-19] days; P=.85), reintubation (5 [31%] vs. 3 [19%]; P=.69), or mortality (4 [20%] vs. 5 [25%] deaths; P=1). Eight patients (40%) in the PSV group and 6 patients (30%) in the PAV group (P=.74) required a return to volume assist-control ventilation due to clinical deterioration. Tolerance, duration of MV and clinical outcomes during weaning from mechanical ventilation were similar in PSV and PAV. Copyright © 2013 Elsevier España, S.L. and SEMICYUC. All rights reserved.

  16. A New Heat Supply System of Cogeneration for the Local Community

    NASA Astrophysics Data System (ADS)

    Yamaguchi, Hideki; Hisazumi, Yoshinori; Asano, Hitoshi; Morita, Hikaru; Hori, Toshihiro; Matsumoto, Toshiki; Abiko, Tetsuo

    In order for economically viable distributed generation systems for local communities to be widely accepted, it is essential to develop an efficient and low-cost heat supply system. For this purpose, we propose a new heat supply system which we already presented at the ICOPE-05 Chicago. The key technology for the system is to connect compact heat supply units with a heat storage function installed in all the households of the local community, such as condominiums, by a single-loop of hot water pipe. A phase change material was used for the heat supply unit as the heat storage material. However, for easier handling and reducing the cost of the unit, we have developed a new heat supply unit whose heat storage tank is made of plastic. Hot water for space heating is used as the heat storage material. Further we constructed a heat supply system for 7 lived-in households with a 5 kW gas engine and a 42 kW boiler as the heat sources. Some experiments with a heat supply unit and a heat supply system, such as for heat storage and heat supply for peak demand were conducted. Additionally, dynamic simulations of heat demand by 50 households and a COP evaluation of a new CO2 heat pump system using low-temperature exhaust gas from the gas engine were also conducted.

  17. Economic, Environmental and Health Implications of Enhanced Ventilation in Office Buildings.

    PubMed

    MacNaughton, Piers; Pegues, James; Satish, Usha; Santanam, Suresh; Spengler, John; Allen, Joseph

    2015-11-18

    Current building ventilation standards are based on acceptable minimums. Three decades of research demonstrates the human health benefits of increased ventilation above these minimums. Recent research also shows the benefits on human decision-making performance in office workers, which translates to increased productivity. However, adoption of enhanced ventilation strategies is lagging. We sought to evaluate two of the perceived potential barriers to more widespread adoption-Economic and environmental costs. We estimated the energy consumption and associated per building occupant costs for office buildings in seven U.S. cities, representing different climate zones for three ventilation scenarios (standard practice (20 cfm/person), 30% enhanced ventilation, and 40 cfm/person) and four different heating, ventilation and air conditioning (HVAC) system strategies (Variable Air Volume (VAV) with reheat and a Fan Coil Unit (FCU), both with and without an energy recovery ventilator). We also estimated emissions of greenhouse gases associated with this increased energy usage, and, for comparison, converted this to the equivalent number of vehicles using greenhouse gas equivalencies. Lastly, we paired results from our previous research on cognitive function and ventilation with labor statistics to estimate the economic benefit of increased productivity associated with increasing ventilation rates. Doubling the ventilation rate from the American Society of Heating, Refrigeration and Air-Conditioning Engineers minimum cost less than $40 per person per year in all climate zones investigated. Using an energy recovery ventilation system significantly reduced energy costs, and in some scenarios led to a net savings. At the highest ventilation rate, adding an ERV essentially neutralized the environmental impact of enhanced ventilation (0.03 additional cars on the road per building across all cities). The same change in ventilation improved the performance of workers by 8

  18. Economic, Environmental and Health Implications of Enhanced Ventilation in Office Buildings

    PubMed Central

    MacNaughton, Piers; Pegues, James; Satish, Usha; Santanam, Suresh; Spengler, John; Allen, Joseph

    2015-01-01

    Introduction: Current building ventilation standards are based on acceptable minimums. Three decades of research demonstrates the human health benefits of increased ventilation above these minimums. Recent research also shows the benefits on human decision-making performance in office workers, which translates to increased productivity. However, adoption of enhanced ventilation strategies is lagging. We sought to evaluate two of the perceived potential barriers to more widespread adoption—Economic and environmental costs. Methods: We estimated the energy consumption and associated per building occupant costs for office buildings in seven U.S. cities, representing different climate zones for three ventilation scenarios (standard practice (20 cfm/person), 30% enhanced ventilation, and 40 cfm/person) and four different heating, ventilation and air conditioning (HVAC) system strategies (Variable Air Volume (VAV) with reheat and a Fan Coil Unit (FCU), both with and without an energy recovery ventilator). We also estimated emissions of greenhouse gases associated with this increased energy usage, and, for comparison, converted this to the equivalent number of vehicles using greenhouse gas equivalencies. Lastly, we paired results from our previous research on cognitive function and ventilation with labor statistics to estimate the economic benefit of increased productivity associated with increasing ventilation rates. Results: Doubling the ventilation rate from the American Society of Heating, Refrigeration and Air-Conditioning Engineers minimum cost less than $40 per person per year in all climate zones investigated. Using an energy recovery ventilation system significantly reduced energy costs, and in some scenarios led to a net savings. At the highest ventilation rate, adding an ERV essentially neutralized the environmental impact of enhanced ventilation (0.03 additional cars on the road per building across all cities). The same change in ventilation improved the

  19. Sound attenuation of fiberglass lined ventilation ducts

    NASA Astrophysics Data System (ADS)

    Albright, Jacob

    Sound attenuation is a crucial part of designing any HVAC system. Most ventilation systems are designed to be in areas occupied by one or more persons. If these systems do not adequately attenuate the sound of the supply fan, compressor, or any other source of sound, the affected area could be subject to an array of problems ranging from an annoying hum to a deafening howl. The goals of this project are to quantify the sound attenuation properties of fiberglass duct liner and to perform a regression analysis to develop equations to predict insertion loss values for both rectangular and round duct liners. The first goal was accomplished via insertion loss testing. The tests performed conformed to the ASTM E477 standard. Using the insertion loss test data, regression equations were developed to predict insertion loss values for rectangular ducts ranging in size from 12-in x 18-in to 48-in x 48-in in lengths ranging from 3ft to 30ft. Regression equations were also developed to predict insertion loss values for round ducts ranging in diameters from 12-in to 48-in in lengths ranging from 3ft to 30ft.

  20. Partial liquid ventilation: effects of closed breathing systems, heat-and-moisture-exchangers and sodalime absorbers on perfluorocarbon evaporation.

    PubMed

    Wilms, C T; Schober, P; Kalb, R; Loer, S A

    2006-01-01

    During partial liquid ventilation perfluorocarbons are instilled into the airways from where they subsequently evaporate via the bronchial system. This process is influenced by multiple factors, such as the vapour pressure of the perfluorocarbons, the instilled volume, intrapulmonary perfluorocarbon distribution, postural positioning and ventilatory settings. In our study we compared the effects of open and closed breathing systems, a heat-and-moisture-exchanger and a sodalime absorber on perfluorocarbon evaporation during partial liquid ventilation. Isolated rat lungs were suspended from a force transducer. After intratracheal perfluorocarbon instillation (10 mL kg(-1)) the lungs were either ventilated with an open breathing system (n = 6), a closed breathing system (n = 6), an open breathing system with an integrated heat-and-moisture-exchanger (n = 6), an open breathing system with an integrated sodalime absorber (n = 6), or a closed breathing system with an integrated heat-and-moisture-exchanger and a sodalime absorber (n = 6). Evaporative perfluorocarbon elimination was determined gravimetrically. When compared to the elimination half-life in an open breathing system (1.2 +/- 0.07 h), elimination half-life was longer with a closed system (6.4 +/- 0.9 h, P 0.05) when compared to a closed system. Evaporative perfluorocarbon loss can be reduced effectively with closed breathing systems, followed by the use of sodalime absorbers and heat-and-moisture-exchangers.

  1. Effect of Ventilation Strategies on Residential Ozone Levels

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Walker, Iain S.; Sherman, Max H.

    Elevated outdoor ozone levels are associated with adverse health effects. Because people spend the vast majority of their time indoors, reduction in indoor levels of ozone of outdoor origin would lower population exposures and might also lead to a reduction in ozone-associated adverse health effects. In most buildings, indoor ozone levels are diminished with respect to outdoor levels to an extent that depends on surface reactions and on the degree to which ozone penetrates the building envelope. Ozone enters buildings from outdoors together with the airflows that are driven by natural and mechanical means, including deliberate ventilation used to reducemore » concentrations of indoor-generated pollutants. When assessing the effect of deliberate ventilation on occupant health one should consider not only the positive effects on removing pollutants of indoor origin but also the possibility that enhanced ventilation might increase indoor levels of pollutants originating outdoors. This study considers how changes in residential ventilation that are designed to comply with ASHRAE Standard 62.2 might influence indoor levels of ozone. Simulation results show that the building envelope can contribute significantly to filtration of ozone. Consequently, the use of exhaust ventilation systems is predicted to produce lower indoor ozone concentrations than would occur with balanced ventilation systems operating at the same air-­exchange rate. We also investigated a strategy for reducing exposure to ozone that would deliberately reduce ventilation rates during times of high outdoor ozone concentration while still meeting daily average ventilation requirements.« less

  2. Direct current uninterruptible power supply method and system

    DOEpatents

    Sinha, Gautam

    2003-12-02

    A method and system are described for providing a direct current (DC) uninterruptible power supply with the method including, for example: continuously supplying fuel to a turbine; converting mechanical power from the turbine into alternating current (AC) electrical power; converting the AC electrical power to DC power within a predetermined voltage level range; supplying the DC power to a load; and maintaining a DC load voltage within the predetermined voltage level range by adjusting the amount of fuel supplied to the turbine.

  3. 24 CFR 3280.710 - Venting, ventilation and combustion air.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Venting, ventilation and combustion... Fuel Burning Systems § 3280.710 Venting, ventilation and combustion air. (a) The venting as required by... appliance listing and the appliance manufacturer's instructions. (b) Venting and combustion air systems...

  4. 24 CFR 3280.710 - Venting, ventilation and combustion air.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 5 2014-04-01 2014-04-01 false Venting, ventilation and combustion... Fuel Burning Systems § 3280.710 Venting, ventilation and combustion air. (a) The venting as required by... appliance listing and the appliance manufacturer's instructions. (b) Venting and combustion air systems...

  5. 24 CFR 3280.710 - Venting, ventilation and combustion air.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 5 2012-04-01 2012-04-01 false Venting, ventilation and combustion... Fuel Burning Systems § 3280.710 Venting, ventilation and combustion air. (a) The venting as required by... appliance listing and the appliance manufacturer's instructions. (b) Venting and combustion air systems...

  6. 24 CFR 3280.710 - Venting, ventilation and combustion air.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Venting, ventilation and combustion... Fuel Burning Systems § 3280.710 Venting, ventilation and combustion air. (a) The venting as required by... appliance listing and the appliance manufacturer's instructions. (b) Venting and combustion air systems...

  7. 24 CFR 3280.710 - Venting, ventilation and combustion air.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Venting, ventilation and combustion... Fuel Burning Systems § 3280.710 Venting, ventilation and combustion air. (a) The venting as required by... appliance listing and the appliance manufacturer's instructions. (b) Venting and combustion air systems...

  8. Troubleshooting of signal power supply system for Shanghai metro line 7

    NASA Astrophysics Data System (ADS)

    Lu, Kaixia; Xiao, Jie

    2018-03-01

    With the rapid development of Urban Rail Transit Signal Technology, the demand of signal power supply system for signal equipment is higher and higher. The signal intelligent power supply panel is the main component of the urban rail traffic signal power supply system. Whether the intelligent power supply panel working or not is directly related to traffic safety. The maintenance of intelligent signal power supply panel is particularly important. Line 7 of Shanghai Metro adopts PMZG Signal Intelligent Power Supply Panel, which is produced by Beijing Jinyujiaxin Polytron Technologies Inc. Maintenance of power supply system mainly includes routine maintenance and troubleshooting. This article will make clear the routine maintenance contents of PMZG Signal Intelligent Power Supply Panel, and put forward the common fault information and troubleshooting methods of PMZG Signal Intelligent Power Supply Panel. In accordance with the steps of fault handling, the faults can be eliminated in the shortest possible time, and PMZG Signal Intelligent Power Supply Panel can be quickly restored to normal working state.

  9. [A design of simple ventilator control system based on LabVIEW].

    PubMed

    Pei, Baoqing; Xu, Shengwei; Li, Hui; Li, Deyu; Pei, Yidong; He, Haixing

    2011-01-01

    This paper designed a ventilator control system to control proportional valves and motors. It used LabVIEW to control the object mentioned above and design ,validate, evaluate arithmetic, and establish hardware in loop platform. There are two system' s hierarchies. The high layer was used to run non-real time program and the low layer was used to run real time program. The two layers communicated through TCP/IP net. The program can be divided into several modules, which can be expanded and maintained easily. And the harvest in the prototype designing can be seamlessly used to embedded products. From all above, this system was useful in employing OEM products.

  10. The long-term performance of electrically charged filters in a ventilation system.

    PubMed

    Raynor, Peter C; Chae, Soo Jae

    2004-07-01

    The efficiency and pressure drop of filters made from polyolefin fibers carrying electrical charges were compared with efficiency and pressure drop for filters made from uncharged glass fibers to determine if the efficiency of the charged filters changed with use. Thirty glass fiber filters and 30 polyolefin fiber filters were placed in different, but nearly identical, air-handling units that supplied outside air to a large building. Using two kinds of real-time aerosol counting and sizing instruments, the efficiency of both sets of filters was measured repeatedly for more than 19 weeks while the air-handling units operated almost continuously. Pressure drop was recorded by the ventilation system's computer control. Measurements showed that the efficiency of the glass fiber filters remained almost constant with time. However, the charged polyolefin fiber filters exhibited large efficiency reductions with time before the efficiency began to increase again toward the end of the test. For particles 0.6 microm in diameter, the efficiency of the polyolefin fiber filters declined from 85% to 45% after 11 weeks before recovering to 65% at the end of the test. The pressure drops of the glass fiber filters increased by about 0.40 in. H2O, whereas the pressure drop of the polyolefin fiber filters increased by only 0.28 in. H2O. The results indicate that dust loading reduces the effectiveness of electrical charges on filter fibers. Copyright 2004 JOEH, LLC

  11. Experimental research on the indoor temperature and humidity fields in radiant ceiling air-conditioning system under natural ventilation

    NASA Astrophysics Data System (ADS)

    Huang, Tao; Xiang, Yutong; Wang, Yonghong

    2017-05-01

    In this paper, the indoor temperature and humidity fields of the air in a metal ceiling radiant panel air conditioning system with fresh air under natural ventilation were researched. The temperature and humidity distributions at different height and different position were compared. Through the computation analysis of partial pressure of water vapor, the self-recovery characteristics of humidity after the natural ventilation was discussed.

  12. Determination of the Zone Endangered by Methane Explosion in Goaf with Caving of Longwalls Ventilated on "Y" System

    NASA Astrophysics Data System (ADS)

    Brodny, Jarosław; Tutak, Magdalena

    2016-12-01

    One of the most dangerous and most commonly present risks in hard coal mines is methane hazard. During exploitation by longwall system with caving, methane is emitted to mine heading from the mined coal and coal left in a pile. A large amount of methane also flows from neighboring seams through cracks and fissures formed in rock mass. In a case of accumulation of explosive methane concentration in goaf zone and with appropriate oxygen concentration and occurrence of initials (e.g. spark or endogenous fire), it may come to the explosion of this gas. In the paper there are presented results of numerical analysis of mixture of air and methane streams flow through the real heading system of a mine, characterized by high methane hazard. The aim of the studies was to analyze the ventilation system of considered heading system and determination of braking zones in goaf zone, in which dangerous and explosive concertation of methane can occur with sufficient oxygen concentration equal to at least 12%. Determination of position of these zones is necessary for the selection of appropriate parameters of the ventilation system to ensure safety of the crew. Analysis of the scale of methane hazard allows to select such a ventilation system of exploitation and neighboring headings that ensures chemical composition of mining atmosphere required by regulation, and required efficiency of methane drainage. The obtained results clearly show that numerical methods, combined with the results of tests in real conditions can be successfully used for the analysis of variants of processes related to ventilation of underground mining, and also in the analysis of emergency states.

  13. [Monitorization of respiratory mechanics in the ventilated patient].

    PubMed

    García-Prieto, E; Amado-Rodríguez, L; Albaiceta, G M

    2014-01-01

    Monitoring during mechanical ventilation allows the measurement of different parameters of respiratory mechanics. Accurate interpretation of these data can be useful for characterizing the situation of the different components of the respiratory system, and for guiding ventilator settings. In this review, we describe the basic concepts of respiratory mechanics, their interpretation, and their potential use in fine-tuning mechanical ventilation. Copyright © 2013 Elsevier España, S.L. y SEMICYUC. All rights reserved.

  14. Improving the current system for supplying organs for transplantation.

    PubMed

    Horton, R L; Horton, P J

    1993-01-01

    The United States currently relies on a voluntary, altruistic system for supplying organs for transplantation. It is now generally recognized that this system, as currently operated, produces a seriously inadequate supply of organs. A number of scholars have argued that some type of (generally unspecified) market system is necessary. Two articles appearing in the Journal of Health Politics, Policy and Law have proposed relatively specific market systems for increasing the supply of organs. In this paper we argue that market systems are at best premature. In particular, there is little to suggest that any type of market system for organs will be permitted in the United States in the foreseeable future. We present data that strongly suggest that the current voluntary, altruistic system has not been developed to its full potential and offer a number of specific suggestions for improving the system.

  15. Are we fully utilizing the functionalities of modern operating room ventilators?

    PubMed

    Liu, Shujie; Kacmarek, Robert M; Oto, Jun

    2017-12-01

    The modern operating room ventilators have become very sophisticated and many of their features are comparable with those of an ICU ventilator. To fully utilize the functionality of modern operating room ventilators, it is important for clinicians to understand in depth the working principle of these ventilators and their functionalities. Piston ventilators have the advantages of delivering accurate tidal volume and certain flow compensation functions. Turbine ventilators have great ability of flow compensation. Ventilation modes are mainly volume-based or pressure-based. Pressure-based ventilation modes provide better leak compensation than volume-based. The integration of advanced flow generation systems and ventilation modes of the modern operating room ventilators enables clinicians to provide both invasive and noninvasive ventilation in perioperative settings. Ventilator waveforms can be used for intraoperative neuromonitoring during cervical spine surgery. The increase in number of new features of modern operating room ventilators clearly creates the opportunity for clinicians to optimize ventilatory care. However, improving the quality of ventilator care relies on a complete understanding and correct use of these new features. VIDEO ABSTRACT: http://links.lww.com/COAN/A47.

  16. MODEL BASED BIOMASS SYSTEM DESIGN OF FEEDSTOCK SUPPLY SYSTEMS FOR BIOENERGY PRODUCTION

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    David J. Muth, Jr.; Jacob J. Jacobson; Kenneth M. Bryden

    Engineering feedstock supply systems that deliver affordable, high-quality biomass remains a challenge for the emerging bioenergy industry. Cellulosic biomass is geographically distributed and has diverse physical and chemical properties. Because of this feedstock supply systems that deliver cellulosic biomass resources to biorefineries require integration of a broad set of engineered unit operations. These unit operations include harvest and collection, storage, preprocessing, and transportation processes. Design decisions for each feedstock supply system unit operation impact the engineering design and performance of the other system elements. These interdependencies are further complicated by spatial and temporal variances such as climate conditions and biomassmore » characteristics. This paper develops an integrated model that couples a SQL-based data management engine and systems dynamics models to design and evaluate biomass feedstock supply systems. The integrated model, called the Biomass Logistics Model (BLM), includes a suite of databases that provide 1) engineering performance data for hundreds of equipment systems, 2) spatially explicit labor cost datasets, and 3) local tax and regulation data. The BLM analytic engine is built in the systems dynamics software package PowersimTM. The BLM is designed to work with thermochemical and biochemical based biofuel conversion platforms and accommodates a range of cellulosic biomass types (i.e., herbaceous residues, short- rotation woody and herbaceous energy crops, woody residues, algae, etc.). The BLM simulates the flow of biomass through the entire supply chain, tracking changes in feedstock characteristics (i.e., moisture content, dry matter, ash content, and dry bulk density) as influenced by the various operations in the supply chain. By accounting for all of the equipment that comes into contact with biomass from the point of harvest to the throat of the conversion facility and the change in

  17. Long-pulse power-supply system for EAST neutral-beam injectors

    NASA Astrophysics Data System (ADS)

    Liu, Zhimin; Jiang, Caichao; Pan, Junjun; Liu, Sheng; Xu, Yongjian; Chen, Shiyong; Hu, Chundong; NBI Team

    2017-05-01

    The long-pulse power-supply system equipped for the 4 MW beam-power ion source is comprised of three units at ASIPP (Institute of Plasma Physics, Chinese Academy of Sciences): one for the neutral-beam test stand and two for the EAST neutral-beam injectors (NBI-1 and NBI-2, respectively). Each power supply system consists of two low voltage and high current DC power supplies for plasma generation of the ion source, and two high voltage and high current DC power supplies for the accelerator grid system. The operation range of the NB power supply is about 80 percent of the design value, which is the safe and stable operation range. At the neutral-beam test stand, a hydrogen ion beam with a beam pulse of 150 s, beam power of 1.5 MW and beam energy of 50 keV was achieved during the long-pulse testing experiments. The result shows that the power-supply system meets the requirements of the EAST-NBIs fully and lays a basis for achieving plasma heating.

  18. Automated ventilator testing.

    PubMed

    Ghaly, J; Smith, A L

    1994-06-01

    A new era has arrived for the Biomedical Engineering Department at the Royal Women's Hospital in Melbourne. We have developed a system to qualitatively test for intermittent or unconfirmed faults, associated with Bear Cub ventilators. Where previous testing has been inadequate, computer logging is now used to interface the RT200 Timeter Calibration Analyser (TCA) to obtain a real time display of data, which can be stored and graphed. Using Quick Basic version 4.5, it was possible to establish communication between the TCA and an IBM compatible computer, such that meaningful displays of machine performance were produced. From the parameters measured it has been possible to obtain data on Peak Pressure, Inspiratory to Expiratory ratio (I:E ratio) Peak Flow and Rate. Monitoring is not limited to these parameters, though these were selected for our particular needs. These parameters are plotted in two ways: 1. Compressed average versus time, up to 24 hours on one screen 2. Raw data, 36 minutes displayed on each screen. The compressed data gives an overview which allows easy identification of intermittent faults. The uncompressed data confirms that the averaged signal is a realistic representation of the situation. One of the major benefits of this type of data analysis, is that ventilator performance may be monitored over a long period of time without requiring the presence of a service technician. It also allows individual ventilator performance to be graphically compared to other ventilators.

  19. Nasal mask ventilation is better than face mask ventilation in edentulous patients.

    PubMed

    Kapoor, Mukul Chandra; Rana, Sandeep; Singh, Arvind Kumar; Vishal, Vindhya; Sikdar, Indranil

    2016-01-01

    Face mask ventilation of the edentulous patient is often difficult as ineffective seating of the standard mask to the face prevents attainment of an adequate air seal. The efficacy of nasal ventilation in edentulous patients has been cited in case reports but has never been investigated. Consecutive edentulous adult patients scheduled for surgery under general anesthesia with endotracheal intubation, during a 17-month period, were prospectively evaluated. After induction of anesthesia and administration of neuromuscular blocker, lungs were ventilated with a standard anatomical face mask of appropriate size, using a volume controlled anesthesia ventilator with tidal volume set at 10 ml/kg. In case of inadequate ventilation, the mask position was adjusted to achieve best-fit. Inspired and expired tidal volumes were measured. Thereafter, the face mask was replaced by a nasal mask and after achieving best-fit, the inspired and expired tidal volumes were recorded. The difference in expired tidal volumes and airway pressures at best-fit with the use of the two masks and number of patients with inadequate ventilation with use of the masks were statistically analyzed. A total of 79 edentulous patients were recruited for the study. The difference in expiratory tidal volumes with the use of the two masks at best-fit was statistically significant (P = 0.0017). Despite the best-fit mask placement, adequacy of ventilation could not be achieved in 24.1% patients during face mask ventilation, and 12.7% patients during nasal mask ventilation and the difference was statistically significant. Nasal mask ventilation is more efficient than standard face mask ventilation in edentulous patients.

  20. History of Mechanical Ventilation. From Vesalius to Ventilator-induced Lung Injury.

    PubMed

    Slutsky, Arthur S

    2015-05-15

    Mechanical ventilation is a life-saving therapy that catalyzed the development of modern intensive care units. The origins of modern mechanical ventilation can be traced back about five centuries to the seminal work of Andreas Vesalius. This article is a short history of mechanical ventilation, tracing its origins over the centuries to the present day. One of the great advances in ventilatory support over the past few decades has been the development of lung-protective ventilatory strategies, based on our understanding of the iatrogenic consequences of mechanical ventilation such as ventilator-induced lung injury. These strategies have markedly improved clinical outcomes in patients with respiratory failure.

  1. Effect of ventilation velocity on hexavalent chromium and isocyanate exposures in aircraft paint spraying.

    PubMed

    Bennett, James; Marlow, David; Nourian, Fariba; Breay, James; Feng, Amy; Methner, Mark

    2018-03-01

    Exposure control system performance was evaluated during aircraft paint spraying at a military facility. Computational fluid dynamics (CFD) modeling, tracer gas testing, and exposure monitoring examined contaminant exposure vs. crossflow ventilation velocity. CFD modeling using the RNG k-ϵ turbulence model showed exposures to simulated methyl isobutyl ketone of 294 and 83.6 ppm, as a spatial average of five worker locations, for velocities of 0.508 and 0.381 m/s (100 and 75 fpm), respectively. In tracer gas experiments, observed supply/exhaust velocities of 0.706/0.503 m/s (136/99 fpm) were termed full-flow, and reduced velocities were termed 3/4-flow and half-flow. Half-flow showed higher tracer gas concentrations than 3/4-flow, which had the lowest time-averaged concentration, with difference in log means significant at the 95% confidence level. Half-flow compared to full-flow and 3/4-flow compared to full-flow showed no statistically significant difference. CFD modeling using these ventilation conditions agreed closely with the tracer results for the full-flow and 3/4-flow comparison, yet not for the 3/4-flow and half-flow comparison. Full-flow conditions at the painting facility produced a velocity of 0.528 m/s (104 fpm) midway between supply and exhaust locations, with the supply rate of 94.4 m 3 /s (200,000 cfm) exceeding the exhaust rate of 68.7 m 3 /s (146,000 cfm). Ventilation modifications to correct this imbalance created a midhangar velocity of 0.406 m/s (80.0 fpm). Personal exposure monitoring for two worker groups-sprayers and sprayer helpers ("hosemen")-compared process duration means for the two velocities. Hexavalent chromium (Cr[VI]) exposures were 500 vs. 360 µg/m 3 for sprayers and 120 vs. 170 µg/m 3 for hosemen, for 0.528 m/s (104 fpm) and 0.406 m/s (80.0 fpm), respectively. Hexamethylene diisocyanate (HDI) monomer means were 32.2 vs. 13.3 µg/m 3 for sprayers and 3.99 vs. 8.42 µg/m 3 for hosemen. Crossflow

  2. Ventilation in the patient with unilateral lung disease.

    PubMed

    Thomas, A R; Bryce, T L

    1998-10-01

    Severe ULD presents a challenge in ventilator management because of the marked asymmetry in the mechanics of the two lungs. The asymmetry may result from significant decreases or increases in the compliance of the involved lung. Traditional ventilator support may fail to produce adequate gas exchange in these situations and has the potential to cause further deterioration. Fortunately, conventional techniques can be safely and effectively applied in the majority of cases without having to resort to less familiar and potentially hazardous forms of support. In those circumstances when conventional ventilation is unsuccessful in restoring adequate gas exchange, lateral positioning and ILV have proved effective at improving and maintaining gas exchange. Controlled trials to guide clinical decision making are lacking. In patients who have processes associated with decreased compliance in the involved lung, lateral positioning may be a simple method of improving gas exchange but is associated with many practical limitations. ILV in these patients is frequently successful when differential PEEP is applied with the higher pressure to the involved lung. In patients in whom the pathology results in distribution of ventilation favoring the involved lung, particularly BPF, ILV can be used to supply adequate support while minimizing flow through the fistula and allowing it to close. The application of these techniques should be undertaken with an understanding of the pathophysiology of the underlying process; the reported experience with these techniques, including indications and successfully applied methods; and the potential problems encountered with their use. Fortunately, these modalities are infrequently required, but they provide a critical means of support when conventional techniques fail.

  3. Public water-supply systems and water use in Tennessee, 1988

    USGS Publications Warehouse

    Hutson, Susan S.; Morris, A. Jannine

    1992-01-01

    This report summarizes the results of a study conducted by the U.S. Geological Survey, in cooperation with the Tennessee Department of Environment and Conservation (TDEC), Division of Water Supply in 1988. Data gathered during an inventory by the TDEC were collated to determine water use, supply sources, population served, and design and storage capacities of the systems. The inventory was limited to systems that were active on June 30, 1988. Results of a survey of the systems conducted by the Tennessee Department of Health and Environment during 1988 were a primary source of data for this report. Data from computer and manual files maintained by the Tennessee Department of Health and Environment and the U.S. Geological Survey also were used. The Division of Water Supply, TDEC, surveyed 541 public water-supply systems. These systems served 81 percent of the population of the State, or 3.95 million people. The gross per capita use statewide for public-supplied water was 179 gallons per day. Total water withdrawals for public supply increased about 39 percent from 510 million gallons per day (Mgal/d) in 1980, to 708 Mgalld in 1988. During the same period, the population increased about 7 percent. Surface-water withdrawals accounted for 63 percent (446 Mgal/d) of the total water withdrawn in the State. All of these withdrawals occurred in the Tennessee (56 percent or 249 Mgal/d) and the Ohio (44 percent or 197 Mgalld) hydrologic regions. Ground water supplied 262 Mgal/d or 37 percent of the total water withdrawn by public-supply systems statewide. Of that amount, 79 percent, or 208 Mgalld, was used in western Tennessee.

  4. Influences of Duration of Inspiratory Effort, Respiratory Mechanics, and Ventilator Type on Asynchrony With Pressure Support and Proportional Assist Ventilation.

    PubMed

    Vasconcelos, Renata S; Sales, Raquel P; Melo, Luíz H de P; Marinho, Liégina S; Bastos, Vasco Pd; Nogueira, Andréa da Nc; Ferreira, Juliana C; Holanda, Marcelo A

    2017-05-01

    Pressure support ventilation (PSV) is often associated with patient-ventilator asynchrony. Proportional assist ventilation (PAV) offers inspiratory assistance proportional to patient effort, minimizing patient-ventilator asynchrony. The objective of this study was to evaluate the influence of respiratory mechanics and patient effort on patient-ventilator asynchrony during PSV and PAV plus (PAV+). We used a mechanical lung simulator and studied 3 respiratory mechanics profiles (normal, obstructive, and restrictive), with variations in the duration of inspiratory effort: 0.5, 1.0, 1.5, and 2.0 s. The Auto-Trak system was studied in ventilators when available. Outcome measures included inspiratory trigger delay, expiratory trigger asynchrony, and tidal volume (V T ). Inspiratory trigger delay was greater in the obstructive respiratory mechanics profile and greatest with a effort of 2.0 s (160 ms); cycling asynchrony, particularly delayed cycling, was common in the obstructive profile, whereas the restrictive profile was associated with premature cycling. In comparison with PSV, PAV+ improved patient-ventilator synchrony, with a shorter triggering delay (28 ms vs 116 ms) and no cycling asynchrony in the restrictive profile. V T was lower with PAV+ than with PSV (630 mL vs 837 mL), as it was with the single-limb circuit ventilator (570 mL vs 837 mL). PAV+ mode was associated with longer cycling delays than were the other ventilation modes, especially for the obstructive profile and higher effort values. Auto-Trak eliminated automatic triggering. Mechanical ventilation asynchrony was influenced by effort, respiratory mechanics, ventilator type, and ventilation mode. In PSV mode, delayed cycling was associated with shorter effort in obstructive respiratory mechanics profiles, whereas premature cycling was more common with longer effort and a restrictive profile. PAV+ prevented premature cycling but not delayed cycling, especially in obstructive respiratory mechanics

  5. Comparison of two humidification systems for long-term noninvasive mechanical ventilation.

    PubMed

    Nava, S; Cirio, S; Fanfulla, F; Carlucci, A; Navarra, A; Negri, A; Ceriana, P

    2008-08-01

    There is no consensus concerning the best system of humidification during long-term noninvasive mechanical ventilation (NIMV). In a technical pilot randomised crossover 12-month study, 16 patients with stable chronic hypercapnic respiratory failure received either heated humidification or heat and moisture exchanger. Compliance with long-term NIMV, airway symptoms, side-effects and number of severe acute pulmonary exacerbations requiring hospitalisation were recorded. Two patients died. Intention-to-treat statistical analysis was performed on 14 patients. No significant differences were observed in compliance with long-term NIMV, but 10 out of 14 patients decided to continue long-term NIMV with heated humidification at the end of the trial. The incidence of side-effects, except for dry throat (significantly more often present using heat and moisture exchanger), hospitalisations and pneumonia were not significantly different. In the present pilot study, the use heated humidification and heat and moisture exchanger showed similar tolerance and side-effects, but a higher number of patients decided to continue long-term noninvasive mechanical ventilation with heated humidification. Further larger studies are required in order to confirm these findings.

  6. Development of an Outdoor Temperature-Based Control Algorithm for Residential Mechanical Ventilation Control

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Less, Brennan; Walker, Iain; Tang, Yihuan

    2014-06-01

    Smart ventilation systems use controls to ventilate more during those periods that provide either an energy or IAQ advantage (or both) and less during periods that provide a dis advantage. Using detailed building simulations, this study addresses one of the simplest and lowest cost types of smart controllers —outdoor temperature- based control. If the outdoor temperature falls below a certain cut- off, the fan is simply turned off. T he main principle of smart ventilation used in this study is to shift ventilation from time periods with large indoor -outdoor temperature differences, to periods where these differences are smaller, andmore » their energy impacts are expected to be less. Energy and IAQ performance are assessed relative to a base case of a continuously operated ventilation fan sized to comply with ASHRAE 62.2-2013 whole house ventilation requirements. In order to satisfy 62.2-2013, annual pollutant exposure must be equivalent between the temperature controlled and continuous fan cases. This requires ventilation to be greater than 62.2 requirements when the ventilation system operates. This is achieved by increasing the mechanical ventilation system air flow rates.« less

  7. Nasal mask ventilation is better than face mask ventilation in edentulous patients

    PubMed Central

    Kapoor, Mukul Chandra; Rana, Sandeep; Singh, Arvind Kumar; Vishal, Vindhya; Sikdar, Indranil

    2016-01-01

    Background and Aims: Face mask ventilation of the edentulous patient is often difficult as ineffective seating of the standard mask to the face prevents attainment of an adequate air seal. The efficacy of nasal ventilation in edentulous patients has been cited in case reports but has never been investigated. Material and Methods: Consecutive edentulous adult patients scheduled for surgery under general anesthesia with endotracheal intubation, during a 17-month period, were prospectively evaluated. After induction of anesthesia and administration of neuromuscular blocker, lungs were ventilated with a standard anatomical face mask of appropriate size, using a volume controlled anesthesia ventilator with tidal volume set at 10 ml/kg. In case of inadequate ventilation, the mask position was adjusted to achieve best-fit. Inspired and expired tidal volumes were measured. Thereafter, the face mask was replaced by a nasal mask and after achieving best-fit, the inspired and expired tidal volumes were recorded. The difference in expired tidal volumes and airway pressures at best-fit with the use of the two masks and number of patients with inadequate ventilation with use of the masks were statistically analyzed. Results: A total of 79 edentulous patients were recruited for the study. The difference in expiratory tidal volumes with the use of the two masks at best-fit was statistically significant (P = 0.0017). Despite the best-fit mask placement, adequacy of ventilation could not be achieved in 24.1% patients during face mask ventilation, and 12.7% patients during nasal mask ventilation and the difference was statistically significant. Conclusion: Nasal mask ventilation is more efficient than standard face mask ventilation in edentulous patients. PMID:27625477

  8. Sunlight supply and gas exchange systems in microalgal bioreactor

    NASA Technical Reports Server (NTRS)

    Mori, K.; Ohya, H.; Matsumoto, K.; Furune, H.

    1987-01-01

    The bioreactor with sunlight supply system and gas exchange systems presented has proved feasible in ground tests and shows much promise for space use as a closed ecological life support system device. The chief conclusions concerning the specification of total system needed for a life support system for a man in a space station are the following: (1) Sunlight supply system - compactness and low electrical consumption; (2) Bioreactor system - high density and growth rate of chlorella; and (3) Gas exchange system - enough for O2 production and CO2 assimilation.

  9. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT: NEW CONDENSATOR, INC.--THE CONDENSATOR DIESEL ENGINE RETROFIT CRANKCASE VENTILATION SYSTEM

    EPA Science Inventory

    EPA's Environmental Technology Verification Program has tested New Condensator Inc.'s Condensator Diesel Engine Retrofit Crankcase Ventilation System. Brake specific fuel consumption (BSFC), the ratio of engine fuel consumption to the engine power output, was evaluated for engine...

  10. Multiplicity in public health supply systems: a learning agenda.

    PubMed

    Bornbusch, Alan; Bates, James

    2013-08-01

    Supply chain integration-merging products for health programs into a single supply chain-tends to be the dominant model in health sector reform. However, multiplicity in a supply system may be justified as a risk management strategy that can better ensure product availability, advance specific health program objectives, and increase efficiency.

  11. Limiting ventilator-induced lung injury through individual electronic medical record surveillance.

    PubMed

    Herasevich, Vitaly; Tsapenko, Mykola; Kojicic, Marija; Ahmed, Adil; Kashyap, Rachul; Venkata, Chakradhar; Shahjehan, Khurram; Thakur, Sweta J; Pickering, Brian W; Zhang, Jiajie; Hubmayr, Rolf D; Gajic, Ognjen

    2011-01-01

    To improve the safety of ventilator care and decrease the risk of ventilator-induced lung injury, we designed and tested an electronic algorithm that incorporates patient characteristics and ventilator settings, allowing near-real-time notification of bedside providers about potentially injurious ventilator settings. Electronic medical records of consecutive patients who received invasive ventilation were screened in three Mayo Clinic Rochester intensive care units. The computer system alerted bedside providers via the text paging notification about potentially injurious ventilator settings. Alert criteria included a Pao2/Fio2 ratio of <300 mm Hg, free text search for the words "edema" or "bilateral + infiltrates" on the chest radiograph report, a tidal volume of >8 mL/kg predicted body weight (based on patient gender and height), a plateau pressure of >30 cm H2O, and a peak airway pressure of >35 cm H2O. Respiratory therapists answered a brief online satisfaction survey. Ventilator-induced lung injury risk was compared before and after the introduction of ventilator-induced lung injury alert. The prevalence of acute lung injury was 42% (n = 490) among 1,159 patients receiving >24 hrs of invasive ventilation. The system sent 111 alerts for 80 patients, with a positive predictive value of 59%. The exposure to potentially injurious ventilation decreased after the intervention from 40.6 ± 74.6 hrs to 26.9 ± 77.3 hrs (p = .004). Electronic medical record surveillance of mechanically ventilated patients accurately detects potentially injurious ventilator settings and is able to influence bedside practice at moderate costs. Its implementation is associated with decreased patient exposure to potentially injurious mechanical ventilation settings.

  12. Public water-supply systems and associated water use in Tennessee, 2005

    USGS Publications Warehouse

    Robinson, John A.; Brooks, Jaala M.

    2010-01-01

    Public water-supply systems in Tennessee provide water to for domestic, industrial, and commercial uses, and municipal services. In 2005, more than 569 public water-supply systems distributed about 920 million gallons per day (Mgal/d) of non-purchased surface water and groundwater to a population of nearly 6 million in Tennessee. Surface-water sources provided 64 percent (about 591 Mgal/d) of the State's water supplies. Groundwater produced from wells and springs in Middle and East Tennessee and from wells in West Tennessee provided 36 percent (about 329 Mgal/d) of the public water supplies. Gross per capita water use for Tennessee in 2005 was about 171 gallons per day. Water withdrawals by public water-supply systems in Tennessee have increased from 250 Mgal/d in 1955 to 920 Mgal/d in 2005. Tennessee public water-supply systems withdraw less groundwater than surface water, and surface-water use has increased at a faster rate than groundwater use. However, 34 systems reported increased groundwater withdrawals during 2000–2005, and 15 of these 34 systems reported increases of 1 Mgal/d or more. The county with the largest surface-water withdrawal rate (130 Mgal/d) was Davidson County. Each of Tennessee's 95 counties was served by at least one public water-supply system in 2005. The largest groundwater withdrawal rate (about 167 Mgal/d) by a single public water-supply system was reported by Memphis Light, Gas and Water, which served 654,267 people in Shelby County in 2005.

  13. 40 CFR 160.45 - Test system supply facilities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Test system supply facilities. 160.45 Section 160.45 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS... be storage areas, as needed, for feed, nutrients, soils, bedding, supplies, and equipment. Storage...

  14. Technical Note: A proposal of air ventilation system design criteria for a clinical room in a heavy-ion medical facility.

    PubMed

    Kum, Oyeon

    2018-06-01

    An optimized air ventilation system design for a treatment room in Heavy-ion Medical Facility is an important issue in the aspects of nuclear safety because the activated air produced in a treatment room can directly affect the medical staff and the general public in the radiation-free area. Optimized design criteria of air ventilation system for a clinical room in 430 MeV/u carbon ion beam medical accelerator facility was performed by using a combination of MCNPX2.7.0 and CINDER'90 codes. Effective dose rate and its accumulated effective dose by inhalation and residual gamma were calculated for a normal treatment scenario (2 min irradiation for one fraction) as a function of decay time. Natural doses around the site were measured before construction and used as reference data. With no air ventilation system, the maximum effective dose rate was about 3 μSv/h (total dose of 90 mSv/y) and minimum 0.2 μSv/h (total dose of 6 mSv/y), which are over the legal limits for medical staff and for the general public. Although inhalation dose contribution was relatively small, it was considered seriously because of its long-lasting effects in the body. The integrated dose per year was 1.8 mSv/y in the radiation-free area with the 20-min rate of air ventilation system. An optimal air ventilation rate of 20 min is proposed for a clinical room, which also agrees with the best mechanical design value. © 2018 American Association of Physicists in Medicine.

  15. Urban community perception towards intermittent water supply system.

    PubMed

    Joshi, M W; Talkhande, A V; Andey, S P; Kelkar, P S

    2002-04-01

    While evaluating intermittent and continuous water supply systems, consumers opinion survey was undertaken for critical appraisal of both modes of operation. With the help of a pre-designed set of questions relating to various aspects of water supply and the opinion of consumers regarding degree of service, a house to house survey was conducted in the study area of Ghaziabad and Jaipur. The consumer opinion survey clearly indicated a satisfactory degree of service wherever adequate quantity of water was made available irrespective of the mode of water supply. Number of complaints regarding quality of water supplied, timings of supply, low pressures and breakdowns in supply were reported during intermittent water supply. Every family stored water for drinking and other uses. Most of the families discard drinking water once the fresh water supply is resumed next day. Discarded drinking water is usually used in kitchen for washing and gardening. Storage for other purposes depends on economic status and availability of other sources like open dug well in the house. While most of the respondents had no complaints on water tariff, all of them were in favour of continuous water supply.

  16. 40 CFR 792.45 - Test system supply facilities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 31 2010-07-01 2010-07-01 true Test system supply facilities. 792.45 Section 792.45 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES... facilities. (a) There shall be storage areas, as needed, for feed, nutrients, soils, bedding, supplies, and...

  17. A supply chain approach to biochar systems [Chapter 2

    Treesearch

    Nathaniel M. Anderson; Richard D. Bergman; Deborah S. Page-Dumroese

    2017-01-01

    Biochar systems are designed to meet four related primary objectives: improve soils, manage waste, generate renewable energy, and mitigate climate change. Supply chain models provide a holistic framework for examining biochar systems with an emphasis on product life cycle and end use. Drawing on concepts in supply chain management and engineering, this chapter presents...

  18. 46 CFR 161.002-9 - Automatic fire detecting system, power supply.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Automatic fire detecting system, power supply. 161.002-9 Section 161.002-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT...-9 Automatic fire detecting system, power supply. The power supply for an automatic fire detecting...

  19. 46 CFR 161.002-9 - Automatic fire detecting system, power supply.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Automatic fire detecting system, power supply. 161.002-9 Section 161.002-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT...-9 Automatic fire detecting system, power supply. The power supply for an automatic fire detecting...

  20. Full-Scale Schlieren Visualization of Commercial Kitchen Ventilation Aerodynamics

    NASA Astrophysics Data System (ADS)

    Miller, J. D.; Settles, G. S.

    1996-11-01

    The efficient removal of cooking effluents from commercial kitchens has been identified as the most pressing energy-related issue in the food service industry. A full-scale schlieren optical system with a 2.1x2.7m field-of-view, described at previous APS/DFD meetings, images the convective airflow associated with a typical gas-fired cooking griddle and ventilation hood. Previous attempts to visualize plumes from cooking equipment by smoke and neutrally-buoyant bubbles were not sufficiently keyed to thermal convection. Here, the point where the ventilation hood fails to capture the effluent plume is clearly visible, thus determining the boundary condition for a balanced ventilation system. Further, the strong influence of turbulent entrainment is seen in the behavior of the combustion products vented by the griddle and the interference caused by a makeup-air outlet located too close to the lip of the ventilation hood. Such applications of traditional fluid dynamics techniques and principles are believed to be important to the maturing of ventilation technology. (Research supported by EPRI and IFMA, Inc.)

  1. Humidification during invasive and noninvasive mechanical ventilation: 2012.

    PubMed

    Restrepo, Ruben D; Walsh, Brian K

    2012-05-01

    We searched the MEDLINE, CINAHL, and Cochrane Library databases for articles published between January 1990 and December 2011. The update of this clinical practice guideline is based on 184 clinical trials and systematic reviews, and 10 articles investigating humidification during invasive and noninvasive mechanical ventilation. The following recommendations are made following the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) scoring system: 1. Humidification is recommended on every patient receiving invasive mechanical ventilation. 2. Active humidification is suggested for noninvasive mechanical ventilation, as it may improve adherence and comfort. 3. When providing active humidification to patients who are invasively ventilated, it is suggested that the device provide a humidity level between 33 mg H(2)O/L and 44 mg H(2)O/L and gas temperature between 34°C and 41°C at the circuit Y-piece, with a relative humidity of 100%. 4. When providing passive humidification to patients undergoing invasive mechanical ventilation, it is suggested that the HME provide a minimum of 30 mg H(2)O/L. 5. Passive humidification is not recommended for noninvasive mechanical ventilation. 6. When providing humidification to patients with low tidal volumes, such as when lung-protective ventilation strategies are used, HMEs are not recommended because they contribute additional dead space, which can increase the ventilation requirement and P(aCO(2)). 7. It is suggested that HMEs are not used as a prevention strategy for ventilator-associated pneumonia.

  2. 46 CFR 108.437 - Pipe sizes and discharge rates for enclosed ventilation systems for rotating electrical equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Pipe sizes and discharge rates for enclosed ventilation systems for rotating electrical equipment. 108.437 Section 108.437 Shipping COAST GUARD, DEPARTMENT OF... Systems Fixed Carbon Dioxide Fire Extinguishing Systems § 108.437 Pipe sizes and discharge rates for...

  3. Accuracy of tidal volume delivered by home mechanical ventilation during mouthpiece ventilation

    PubMed Central

    Prigent, Helene; Falaize, Line; Leroux, Karl; Santos, Dante; Vaugier, Isabelle; Orlikowski, David; Lofaso, Frederic

    2016-01-01

    The aim of our study was to evaluate efficacy and reliability of currently available ventilators for mouthpiece ventilation (MPV). Five life-support home ventilators were assessed in a bench test using different settings simulating the specificities of MPV, such as intermittent circuit disconnection and presence of continuous leaks. The intermittent disconnection of the circuit caused relevant swings in the delivered tidal volume (VT), showing a VT overshoot during the disconnection periods and a VT decrease when the interface was reconnected to the test lung. The five ventilators showed substantial differences in the number of respiratory cycles necessary to reach a stable VT in the volume-controlled setting, ranging from 1.3 ± 0.6 to 7.3 ± 1.2 cycles. These differences were less accentuated in the volume-assisted setting (MPV-dedicated mode, when available). Our data show large differences in the capacity of the different ventilators to deal with the rapidly changing respiratory load features that characterize MPV, which can be further accentuated according to the used ventilator setting. The dedicated MPV modes allow improvement in the performance of ventilators only in some defined situations. This has practical consequences for the choice of the ventilator to be used for MPV in a specific patient. PMID:27146811

  4. Smart ventilation energy and indoor air quality performance in residential buildings: A review

    DOE PAGES

    Guyot, Gaelle; Sherman, Max H.; Walker, Iain S.

    2017-12-30

    To better address energy and indoor air quality issues, ventilation needs to become smarter. A key smart ventilation concept is to use controls to ventilate more at times it provides either an energy or indoor air quality (IAQ) advantage (or both) and less when it provides a disadvantage. A favorable context exists in many countries to include some of the existing smart ventilation strategies in codes and standards. As a result, demand-controlled ventilation (DCV) systems are widely and easily available on the market, with more than 20 DCV systems approved and available in countries such as Belgium, France and themore » Netherlands. This paper provides a literature review on smart ventilation used in residential buildings, based on energy and indoor air quality performance. This meta-analysis includes 38 studies of various smart ventilation systems with control based on CO 2, humidity, combined CO 2 and total volatile organic compounds (TVOC), occupancy, or outdoor temperature. In conclusion, these studies show that ventilation energy savings up to 60% can be obtained without compromising IAQ, even sometimes improving it. However, the meta-analysis included some less than favorable results, with 26% energy overconsumption in some cases.« less

  5. Smart ventilation energy and indoor air quality performance in residential buildings: A review

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Guyot, Gaelle; Sherman, Max H.; Walker, Iain S.

    To better address energy and indoor air quality issues, ventilation needs to become smarter. A key smart ventilation concept is to use controls to ventilate more at times it provides either an energy or indoor air quality (IAQ) advantage (or both) and less when it provides a disadvantage. A favorable context exists in many countries to include some of the existing smart ventilation strategies in codes and standards. As a result, demand-controlled ventilation (DCV) systems are widely and easily available on the market, with more than 20 DCV systems approved and available in countries such as Belgium, France and themore » Netherlands. This paper provides a literature review on smart ventilation used in residential buildings, based on energy and indoor air quality performance. This meta-analysis includes 38 studies of various smart ventilation systems with control based on CO 2, humidity, combined CO 2 and total volatile organic compounds (TVOC), occupancy, or outdoor temperature. In conclusion, these studies show that ventilation energy savings up to 60% can be obtained without compromising IAQ, even sometimes improving it. However, the meta-analysis included some less than favorable results, with 26% energy overconsumption in some cases.« less

  6. Study of Alternate Material for Pedal Ventilator Kits.

    DTIC Science & Technology

    1980-04-01

    to fans with diameters of 36 inches or less, revealed that a shelter ventilation system of minimum cost would require three units with 36-inch...doorways, it was decided, with OCD approval, to develop pre-assembled one and two-operator bicycle ventilator kits utilizing a fan and ducting system of...polypropylene matrix. According to Ford Motor Company, an enthusiastic user, this material hybrid offers large potential savings in direct substitution for glass

  7. Oral mask ventilation is more effective than face mask ventilation after nasal surgery.

    PubMed

    Yazicioğlu, Dilek; Baran, Ilkay; Uzumcugil, Filiz; Ozturk, Ibrahim; Utebey, Gulten; Sayın, M Murat

    2016-06-01

    To evaluate and compare the face mask (FM) and oral mask (OM) ventilation techniques during anesthesia emergence regarding tidal volume, leak volume, and difficult mask ventilation (DMV) incidence. Prospective, randomized, crossover study. Operating room, training and research hospital. American Society of Anesthesiologists physical status I and II adult patients scheduled for nasal surgery. Patients in group FM-OM received FM ventilation first, followed by OM ventilation, and patients in group OM-FM received OM ventilation first, followed by FM ventilation, with spontaneous ventilation after deep extubation. The FM ventilation was applied with the 1-handed EC-clamp technique. The OM was placed only over the mouth, and the 1-handed EC-clamp technique was used again. A child's size FM was used for the OM ventilation technique, the mask was rotated, and the inferior part of the mask was placed toward the nose. The leak volume (MVleak), mean airway pressure (Pmean), and expired tidal volume (TVe) were assessed with each mask technique for 3 consecutive breaths. A mask ventilation grade ≥3 was considered DMV. DMV occurred more frequently during FM ventilation (75% with FM vs 8% with OM). In the FM-first sequence, the mean TVe was 249±61mL with the FM and 455±35mL with the OM (P=.0001), whereas in the OM-first sequence, it was 276±81mL with the FM and 409±37mL with the OM (P=.0001). Regardless of the order used, the OM technique significantly decreased the MVleak and increased the TVe when compared to the FM technique. During anesthesia emergence after nasal surgery the OM may offer an effective ventilation method as it decreases the incidence of DMV and the gas leak around the mask and provides higher tidal volume delivery compared with FM ventilation. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. Pediatric Ventilator-Associated Infections: The Ventilator-Associated INfection Study.

    PubMed

    Willson, Douglas F; Hoot, Michelle; Khemani, Robinder; Carrol, Christopher; Kirby, Aileen; Schwarz, Adam; Gedeit, Rainer; Nett, Sholeen T; Erickson, Simon; Flori, Heidi; Hays, Spencer; Hall, Mark

    2017-01-01

    Suspected ventilator-associated infection is the most common reason for antibiotics in the PICU. We sought to characterize the clinical variables associated with continuing antibiotics after initial evaluation for suspected ventilator-associated infection and to determine whether clinical variables or antibiotic treatment influenced outcomes. Prospective, observational cohort study conducted in 47 PICUs in the United States, Canada, and Australia. Two hundred twenty-nine pediatric patients ventilated more than 48 hours undergoing respiratory secretion cultures were enrolled as "suspected ventilator-associated infection" in a prospective cohort study, those receiving antibiotics of less than or equal to 3 days were categorized as "evaluation only," and greater than 3 days as "treated." Demographics, diagnoses, comorbidities, culture results, and clinical data were compared between evaluation only and treated subjects and between subjects with positive versus negative cultures. PICUs in 47 hospitals in the United States, Canada, and Australia. All patients undergoing respiratory secretion cultures during the 6 study periods. None. Treated subjects differed from evaluation-only subjects only in frequency of positive cultures (79% vs 36%; p < 0.0001). Subjects with positive cultures were more likely to have chronic lung disease, tracheostomy, and shorter PICU stay, but there were no differences in ventilator days or mortality. Outcomes were similar in subjects with positive or negative cultures irrespective of antibiotic treatment. Immunocompromise and higher Pediatric Logistic Organ Dysfunction scores were the only variables associated with mortality in the overall population, but treated subjects with endotracheal tubes had significantly lower mortality. Positive respiratory cultures were the primary determinant of continued antibiotic treatment in children with suspected ventilator-associated infection. Positive cultures were not associated with worse outcomes

  9. [The development of hospital medical supplies information management system].

    PubMed

    Cao, Shaoping; Gu, Hongqing; Zhang, Peng; Wang, Qiang

    2010-05-01

    The information management of medical materials by using high-tech computer, in order to improve the efficiency of the consumption of medical supplies, hospital supplies and develop a new technology way to manage the hospital and material support. Using C # NET, JAVA techniques to develop procedures for the establishment of hospital material management information system, set the various management modules, production of various statistical reports, standard operating procedures. The system is convenient, functional and strong, fluent statistical functions. It can always fully grasp and understand the whole hospital supplies run dynamic information, as a modern and effective tool for hospital materials management.

  10. Inhibition of forkhead boxO-specific transcription prevents mechanical ventilation-induced diaphragm dysfunction.

    PubMed

    Smuder, Ashley J; Sollanek, Kurt J; Min, Kisuk; Nelson, W Bradley; Powers, Scott K

    2015-05-01

    Mechanical ventilation is a lifesaving measure for patients with respiratory failure. However, prolonged mechanical ventilation results in diaphragm weakness, which contributes to problems in weaning from the ventilator. Therefore, identifying the signaling pathways responsible for mechanical ventilation-induced diaphragm weakness is essential to developing effective countermeasures to combat this important problem. In this regard, the forkhead boxO family of transcription factors is activated in the diaphragm during mechanical ventilation, and forkhead boxO-specific transcription can lead to enhanced proteolysis and muscle protein breakdown. Currently, the role that forkhead boxO activation plays in the development of mechanical ventilation-induced diaphragm weakness remains unknown. This study tested the hypothesis that mechanical ventilation-induced increases in forkhead boxO signaling contribute to ventilator-induced diaphragm weakness. University research laboratory. Young adult female Sprague-Dawley rats. Cause and effect was determined by inhibiting the activation of forkhead boxO in the rat diaphragm through the use of a dominant-negative forkhead boxO adeno-associated virus vector delivered directly to the diaphragm. Our results demonstrate that prolonged (12 hr) mechanical ventilation results in a significant decrease in both diaphragm muscle fiber size and diaphragm-specific force production. However, mechanically ventilated animals treated with dominant-negative forkhead boxO showed a significant attenuation of both diaphragm atrophy and contractile dysfunction. In addition, inhibiting forkhead boxO transcription attenuated the mechanical ventilation-induced activation of the ubiquitin-proteasome system, the autophagy/lysosomal system, and caspase-3. Forkhead boxO is necessary for the activation of key proteolytic systems essential for mechanical ventilation-induced diaphragm atrophy and contractile dysfunction. Collectively, these results suggest that

  11. Effect of enhanced ultraviolet germicidal irradiation in the heating ventilation and air conditioning system on ventilator-associated pneumonia in a neonatal intensive care unit.

    PubMed

    Ryan, R M; Wilding, G E; Wynn, R J; Welliver, R C; Holm, B A; Leach, C L

    2011-09-01

    The objective of this study was to test the hypothesis that enhanced ultraviolet germicidal irradiation (eUVGI) installed in our neonatal intensive care unit (NICU) heating ventilation and air conditioning system (HVAC) would decrease HVAC and NICU environment microbes, tracheal colonization and ventilator-associated pneumonia (VAP). The study was designed as a prospective interventional pre- and post-single-center study. University-affiliated Regional Perinatal Center NICU. Intubated patients in the NICU were evaluated for colonization, and a high-risk sub-population of infants <30 weeks gestation ventilated for ≥ 14 days was studied for VAP. eUVGI was installed in the NICU's remote HVACs. The HVACs, NICU environment and intubated patients' tracheas were cultured pre- and post-eUVGI for 12 months. The high-risk patients were studied for VAP (positive bacterial tracheal culture, increased ventilator support, worsening chest radiograph and ≥ 7 days of antibiotics). Pseudomonas, Klebsiella, Serratia, Acinetobacter, Staphylococcus aureus and Coagulase-negative Staphylococcus species were cultured from all sites. eUVGI significantly decreased HVAC organisms (baseline 500,000 CFU cm(-2); P=0.015) and NICU environmental microbes (P<0.0001). Tracheal microbial loads decreased 45% (P=0.004), and fewer patients became colonized. VAP in the high-risk cohort fell from 74% (n=31) to 39% (n=18), P=0.04. VAP episodes per patient decreased (Control: 1.2 to eUVGI: 0.4; P=0.004), and antibiotic usage was 62% less (P=0.013). eUVGI decreased HVAC microbial colonization and was associated with reduced NICU environment and tracheal microbial colonization. Significant reductions in VAP and antibiotic use were also associated with eUVGI in this single-center study. Large randomized multicenter trials are needed.

  12. [Anesthesiological systems "Polinarkon-Vita" with microprocessor for artificial lung ventilation apparatuses and monitoring].

    PubMed

    Trushin, A I; Uliakov, G I; Reĭderman, E N

    2005-01-01

    The anesthesiological systems Polinarkon-Vita for adults and children are described. These systems were developed at VNIIMP-VITA, Ltd. on the basis of basic model of the anesthesiological system Polinarkon-E-Vita. The following new important units of the fifth generation apparatuses for inhalation anesthesia (IA) are described: Anestezist-4 monocomponent evaporator for liquid anesthetics (enfluran and isofluran); Diana, Diana-Det, and Elan-NR apparatuses for mechanical lung ventilation (MLV); dosimeters of medical gases, etc. These systems implement monitoring of vitally important functions of patient and parameters of IN and MLV. The anesthesiological systems Polinarkon-Vita are recommended for medical practice and commercially available from VNIIMP-VITA, Ltd. as small lots.

  13. On adaptive modified projective synchronization of a supply chain management system

    NASA Astrophysics Data System (ADS)

    Tirandaz, Hamed

    2017-12-01

    In this paper, the synchronization problem of a chaotic supply chain management system is studied. A novel adaptive modified projective synchronization method is introduced to control the behaviour of the leader supply chain system by a follower chaotic system and to adjust the leader system parameters until the measurable errors of the system parameters converge to zero. The stability evaluation and convergence analysis are carried out by the Lyapanov stability theorem. The proposed synchronization and antisynchronization techniques are studied for identical supply chain chaotic systems. Finally, some numerical simulations are presented to verify the effectiveness of the theoretical discussions.

  14. Negative pressure ventilation and positive pressure ventilation promote comparable levels of ventilator-induced diaphragmatic dysfunction in rats.

    PubMed

    Bruells, Christian S; Smuder, Ashley J; Reiss, Lucy K; Hudson, Matthew B; Nelson, William Bradley; Wiggs, Michael P; Sollanek, Kurt J; Rossaint, Rolf; Uhlig, Stefan; Powers, Scott K

    2013-09-01

    Mechanical ventilation is a life-saving intervention for patients with respiratory failure. Unfortunately, a major complication associated with prolonged mechanical ventilation is ventilator-induced diaphragmatic atrophy and contractile dysfunction, termed ventilator-induced diaphragmatic dysfunction (VIDD). Emerging evidence suggests that positive pressure ventilation (PPV) promotes lung damage (ventilator-induced lung injury [VILI]), resulting in the release of signaling molecules that foster atrophic signaling in the diaphragm and the resultant VIDD. Although a recent report suggests that negative pressure ventilation (NPV) results in less VILI than PPV, it is unknown whether NPV can protect against VIDD. Therefore, the authors tested the hypothesis that compared with PPV, NPV will result in a lower level of VIDD. Adult rats were randomly assigned to one of three experimental groups (n = 8 each): (1) acutely anesthetized control (CON), (2) 12 h of PPV, and (3) 12 h of NPV. Dependent measures included indices of VILI, diaphragmatic muscle fiber cross-sectional area, diaphragm contractile properties, and the activity of key proteases in the diaphragm. Our results reveal that no differences existed in the degree of VILI between PPV and NPV animals as evidenced by VILI histological scores (CON = 0.082 ± 0.001; PPV = 0.22 ± 0.04; NPV = 0.25 ± 0.02; mean ± SEM). Both PPV and NPV resulted in VIDD. Importantly, no differences existed between PPV and NPV animals in diaphragmatic fiber cross-sectional area, contractile properties, and the activation of proteases. These results demonstrate that NPV and PPV result in similar levels of VILI and that NPV and PPV promote comparable levels of VIDD in rats.

  15. 46 CFR 177.600 - Ventilation of enclosed and partially enclosed spaces.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Ventilation of enclosed and partially enclosed spaces... enclosed and partially enclosed spaces. (a) An enclosed or partially enclosed space within a vessel must be adequately ventilated in a manner suitable for the purpose of the space. (b) A power ventilation system must...

  16. 46 CFR 116.600 - Ventilation of enclosed and partially enclosed spaces.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Ventilation of enclosed and partially enclosed spaces... spaces. (a) An enclosed or partially enclosed space within a vessel must be adequately ventilated in a manner suitable for the purpose of the space. (b) A power ventilation system must be capable of being...

  17. 46 CFR 116.600 - Ventilation of enclosed and partially enclosed spaces.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Ventilation of enclosed and partially enclosed spaces... spaces. (a) An enclosed or partially enclosed space within a vessel must be adequately ventilated in a manner suitable for the purpose of the space. (b) A power ventilation system must be capable of being...

  18. 46 CFR 116.600 - Ventilation of enclosed and partially enclosed spaces.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Ventilation of enclosed and partially enclosed spaces... spaces. (a) An enclosed or partially enclosed space within a vessel must be adequately ventilated in a manner suitable for the purpose of the space. (b) A power ventilation system must be capable of being...

  19. 46 CFR 177.600 - Ventilation of enclosed and partially enclosed spaces.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Ventilation of enclosed and partially enclosed spaces... enclosed and partially enclosed spaces. (a) An enclosed or partially enclosed space within a vessel must be adequately ventilated in a manner suitable for the purpose of the space. (b) A power ventilation system must...

  20. 46 CFR 177.600 - Ventilation of enclosed and partially enclosed spaces.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Ventilation of enclosed and partially enclosed spaces... enclosed and partially enclosed spaces. (a) An enclosed or partially enclosed space within a vessel must be adequately ventilated in a manner suitable for the purpose of the space. (b) A power ventilation system must...

  1. 46 CFR 116.600 - Ventilation of enclosed and partially enclosed spaces.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Ventilation of enclosed and partially enclosed spaces... spaces. (a) An enclosed or partially enclosed space within a vessel must be adequately ventilated in a manner suitable for the purpose of the space. (b) A power ventilation system must be capable of being...

  2. 46 CFR 116.600 - Ventilation of enclosed and partially enclosed spaces.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Ventilation of enclosed and partially enclosed spaces... spaces. (a) An enclosed or partially enclosed space within a vessel must be adequately ventilated in a manner suitable for the purpose of the space. (b) A power ventilation system must be capable of being...

  3. 46 CFR 177.600 - Ventilation of enclosed and partially enclosed spaces.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Ventilation of enclosed and partially enclosed spaces... enclosed and partially enclosed spaces. (a) An enclosed or partially enclosed space within a vessel must be adequately ventilated in a manner suitable for the purpose of the space. (b) A power ventilation system must...

  4. 46 CFR 177.600 - Ventilation of enclosed and partially enclosed spaces.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Ventilation of enclosed and partially enclosed spaces... enclosed and partially enclosed spaces. (a) An enclosed or partially enclosed space within a vessel must be adequately ventilated in a manner suitable for the purpose of the space. (b) A power ventilation system must...

  5. Effectiveness of photocatalytic filter for removing volatile organic compounds in the heating, ventilation, and air conditioning system.

    PubMed

    Yu, Kuo-Pin; Lee, Grace Whei-May; Huang, Wei-Ming; Wu, Chih-Cheng; Lou, Chia-ling; Yang, Shinhao

    2006-05-01

    Nowadays, the heating, ventilation, and air conditioning (HVAC) system has been an important facility for maintaining indoor air quality. However, the primary function of typical HVAC systems is to control the temperature and humidity of the supply air. Most indoor air pollutants, such as volatile organic compounds (VOCs), cannot be removed by typical HVAC systems. Thus, some air handling units for removing VOCs should be added in typical HVAC systems. Among all of the air cleaning techniques used to remove indoor VOCs, photocatalytic oxidation is an attractive alternative technique for indoor air purification and deodorization. The objective of this research is to investigate the VOC removal efficiency of the photocatalytic filter in a HVAC system. Toluene and formaldehyde were chosen as the target pollutants. The experiments were conducted in a stainless steel chamber equipped with a simplified HVAC system. A mechanical filter coated with Degussa P25 titania photocatalyst and two commercial photocatalytic filters were used as the photocatalytic filters in this simplified HVAC system. The total air change rates were controlled at 0.5, 0.75, 1, 1.25, and 1.5 hr(-1), and the relative humidity (RH) was controlled at 30%, 50%, and 70%. The ultraviolet lamp used was a 4-W, ultraviolet-C (central wavelength at 254 nm) strip light bulb. The first-order decay constant of toluene and formaldehyde found in this study ranged from 0.381 to 1.01 hr(-1) under different total air change rates, from 0.34 to 0.433 hr(-1) under different RH, and from 0.381 to 0.433 hr(-1) for different photocatalytic filters.

  6. 77 FR 48177 - Fuel Oil Systems for Emergency Power Supplies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-13

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0159] Fuel Oil Systems for Emergency Power Supplies AGENCY: Nuclear Regulatory Commission. ACTION: Draft regulatory guide; extension of comment period. SUMMARY: On... Regulatory Guide, DG- 1282, ``Fuel Oil Systems for Emergency Power Supplies,'' in the Federal Register for a...

  7. Are tidal volume measurements in neonatal pressure-controlled ventilation accurate?

    PubMed

    Chow, Lily C; Vanderhal, Andre; Raber, Jorge; Sola, Augusto

    2002-09-01

    Bedside pulmonary mechanics monitors (PMM) have become useful in ventilatory management in neonates. These monitors are used more frequently due to recent improvements in data-processing capabilities. PMM devices are often part of the ventilator or are separate units. The accuracy and reliability of these systems have not been carefully evaluated. We compared a single ventilatory parameter, tidal volume (V(t)), as measured by several systems. We looked at two freestanding PMMs: the Ventrak Respiratory Monitoring System (Novametrix, Wallingford, CT) and the Bicore CP-100 Neonatal Pulmonary Monitor (Allied Health Care Products, Riverside, CA), and three ventilators with built-in PMM: the VIP Bird Ventilator (Bird Products Corp., Palm Springs, CA), Siemens Servo 300A (Siemens-Elema AB, Solna, Sweden), and Drager Babylog 8000 (Drager, Inc., Chantilly, VA). A calibrated syringe (Hans Rudolph, Inc., Kansas City, MO) was used to deliver tidal volumes of 4, 10, and 20 mL to each ventilator system coupled with a freestanding PMM. After achieving steady state, six consecutive V(t) readings were taken simultaneously from the freestanding PMM and each ventilator. In a second portion of the bench study, we used pressure-control ventilation and measured exhaled tidal volume (V(te)) while ventilating a Bear Test Lung with the same three ventilators. We adjusted peak inspiratory pressure (PIP) under controlled conditions to achieve the three different targeted tidal volumes on the paired freestanding PMM. Again, six V(te) measurements were recorded for each tidal volume. Means and standard deviations were calculated.The percentage difference in measurement of V(t) delivered by calibrated syringe varied greatly, with the greatest discrepancy seen in the smallest tidal volumes, by up to 28%. In pressure control mode, V(te) as measured by the Siemens was significantly overestimated by 20-95%, with the biggest discrepancy at the smallest V(te), particularly when paired with the Bicore

  8. Decommissioning of Active Ventilation Systems in a Nuclear R and D Facility to Prepare for Building Demolition (Whiteshell Laboratories Decommissioning Project, Canada) - 13073

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wilcox, Brian; May, Doug; Howlett, Don

    2013-07-01

    Whiteshell Laboratories (WL) is a nuclear research establishment owned by the Canadian government and operated by Atomic Energy of Canada Limited (AECL) since the early 1960's. WL is currently under a decommissioning license and the mandate is to remediate the nuclear legacy liabilities in a safe and cost effective manner. The WL Project is the first major nuclear decommissioning project in Canada. A major initiative underway is to decommission and demolish the main R and D Laboratory complex. The Building 300 R and D complex was constructed to accommodate laboratories and offices which were mainly used for research and developmentmore » associated with organic-cooled reactors, nuclear fuel waste management, reactor safety, advanced fuel cycles and other applications of nuclear energy. Building 300 is a three storey structure of approximately 16,000 m{sup 2}. In order to proceed with building demolition, the contaminated systems inside the building have to be characterized, removed, and the waste managed. There is a significant focus on volume reduction of radioactive waste for the WL project. The active ventilation system is one of the significant contaminated systems in Building 300 that requires decommissioning and removal. The active ventilation system was designed to manage hazardous fumes and radioactivity from ventilation devices (e.g., fume hoods, snorkels and glove boxes) and to prevent the escape of airborne hazardous material outside of the laboratory boundary in the event of an upset condition. The system includes over 200 ventilation devices and 32 active exhaust fan units and high efficiency particulate air (HEPA) filters. The strategy to remove the ventilation system was to work from the laboratory end back to the fan/filter system. Each ventilation duct was radiologically characterized. Fogging was used to minimize loose contamination. Sections of the duct were removed by various cutting methods and bagged for temporary storage prior to

  9. Gas exchange and intrapulmonary distribution of ventilation during continuous-flow ventilation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vettermann, J.; Brusasco, V.; Rehder, K.

    1988-05-01

    In 12 anesthetized paralyzed dogs, pulmonary gas exchange and intrapulmonary inspired gas distribution were compared between continuous-flow ventilation (CFV) and conventional mechanical ventilation (CMV). Nine dogs were studied while they were lying supine, and three dogs were studied while they were lying prone. A single-lumen catheter for tracheal insufflation and a double-lumen catheter for bilateral endobronchial insufflation (inspired O2 fraction = 0.4; inspired minute ventilation = 1.7 +/- 0.3 (SD) 1.kg-1.min-1) were evaluated. Intrapulmonary gas distribution was assessed from regional 133Xe clearances. In dogs lying supine, CO2 elimination was more efficient with endobronchial insufflation than with tracheal insufflation, but themore » alveolar-arterial O2 partial pressure difference was larger during CFV than during CMV, regardless of the type of insufflation. By contrast, endobronchial insufflation maintained both arterial PCO2 and alveolar-arterial O2 partial pressure difference at significantly lower levels in dogs lying prone than in dogs lying supine. In dogs lying supine, the dependent lung was preferentially ventilated during CMV but not during CFV. In dogs lying prone, gas distribution was uniform with both modes of ventilation. The alveolar-arterial O2 partial pressure difference during CFV in dogs lying supine was negatively correlated with the reduced ventilation of the dependent lung, which suggests that increased ventilation-perfusion mismatching was responsible for the increase in alveolar-arterial O2 partial pressure difference. The more efficient oxygenation during CFV in dogs lying prone suggests a more efficient matching of ventilation to perfusion, presumably because the distribution of blood flow is also nearly uniform.« less

  10. A Study on The Development of Local Exhaust Ventilation System (LEV’s) for Installation of Laser Cutting Machine

    NASA Astrophysics Data System (ADS)

    Harun, S. I.; Idris, S. R. A.; Tamar Jaya, N.

    2017-09-01

    Local exhaust ventilation (LEV) is an engineering system frequently used in the workplace to protect operators from hazardous substances. The objective of this project is design and fabricate the ventilation system as installation for chamber room of laser cutting machine and to stimulate the air flow inside chamber room of laser cutting machine with the ventilation system that designed. LEV’s fabricated with rated voltage D.C 10.8V and 1.5 ampere. Its capacity 600 ml, continuously use limit approximately 12-15 minute, overall length LEV’s fabricated is 966 mm with net weight 0.88 kg and maximum airflow is 1.3 meter cubic per minute. Stimulate the air flow inside chamber room of laser cutting machine with the ventilation system that designed and fabricated overall result get 2 main gas vapor which air and carbon dioxide. For air gas which experimented by using anemometer, general duct velocity that produce is same with other gas produce, carbon dioxide which 5 m/s until 10 m/s. Overall result for 5 m/s and 10 m/s as minimum and maximum duct velocity produce for both air and carbon dioxide. The air gas flow velocity that captured by LEV’s fabricated, 3.998 m/s average velocity captured from 5 m/s duct velocity which it efficiency of 79.960% and 7.667 m/s average velocity captured from 10 m/s duct velocity with efficiency of 76.665%. For carbon dioxide gas flow velocity that captured by LEV’s fabricated, 3.674 m/s average velocity captured from 5 m/s duct velocity which it efficiency of 73.480% and 8.255 m/s average velocity captured from 10 m/s duct velocity with efficiency of 82.545%.

  11. Evaluation of a Shaker Dust Collector for Use in a Recirculating Ventilation System

    PubMed Central

    Sawvel, Russell A.; Park, Jae Hong; Anthony, T. Renée

    2016-01-01

    General ventilation with recirculated air may be cost-effective to control the concentration of low-toxicity, contaminants in workplaces with diffuse, dusty operations, such as in agriculture. Such systems are, however, rarely adopted with little evidence showing improved air quality and ability to operate under harsh conditions. The goal of this work was to examine the initial and long-term performance of a fabric-filter shaker dust collector (SDC) in laboratory tests and as deployed within a recirculating ventilation system in an agricultural building. In laboratory tests, collection efficiency and pressure drop were tracked over several filter loading cycles, and the recovery of filter capacity (pressure drop) from filter shaking was examined. Collection efficiencies of particles larger than 5 μm was high (>95%) even when the filter was pristine, showing effective collection of large particles that dominate inhalable concentrations typical of agricultural dusts. For respirable-sized particles, collection efficiencies were low when the filter was pristine (e.g., 27% for 1 μm) but much higher when a dust cake developed on the filter (>99% for all size particles), even after shaking (e.g., 90% for 1 μm). The first shake of a filter was observed to recovery a substantial fraction of filter capacity, with subsequent shakes providing little benefit. In field tests, the SDC performed effectively over a period of three months in winter when incorporated in a recirculating ventilation system of a swine farrowing room. Trends in collection efficiency and pressure drop with loading were similar to those observed in the laboratory with overall collection efficiencies high (>80%) when pressure drop exceeded 230 Pa, or 23% of the maximum loading recommended by the manufacturer. This work shows that the SDC can function effectively over the harsh winter in swine rearing operations. Together with findings of improved air quality in the farrowing room reported in a companion

  12. Magnetic Resonance Imaging of Ventilation and Perfusion in the Lung

    NASA Technical Reports Server (NTRS)

    Prisk, Gordon Kim (Inventor); Hopkins, Susan Roberta (Inventor); Pereira De Sa, Rui Carlos (Inventor); Theilmann, Rebecca Jean (Inventor); Buxton, Richard Bruce (Inventor); Cronin, Matthew Vincent (Inventor)

    2017-01-01

    Methods, devices, and systems are disclosed for implementing a fully quantitative non-injectable contrast proton MRI technique to measure spatial ventilation-perfusion (VA/Q) matching and spatial distribution of ventilation and perfusion. In one aspect, a method using MRI to characterize ventilation and perfusion in a lung includes acquiring an MR image of the lung having MR data in a voxel and obtaining a breathing frequency parameter, determining a water density value, a specific ventilation value, and a perfusion value in at least one voxel of the MR image based on the MR data and using the water density value to determine an air content value, and determining a ventilation-perfusion ratio value that is the product of the specific ventilation value, the air content value, the inverse of the perfusion value, and the breathing frequency.

  13. An intelligent traceability system: Efficient tool for a supply chain sustainability

    NASA Astrophysics Data System (ADS)

    Bougdira, Abdesselam; Ahaitouf, Abdelaziz; Akharraz, Ismail

    2016-07-01

    The supply chain sustainability becomes a necessity for a smooth, a rapid and a fluid economic transaction. To reach a sustainable supply chain, we propose to focus attention on products and their lifecycle. So, we consider the traceability as a major success key to ensure the supply chain sustainability. For that, we consider a supply chain design that use an intelligent products traced by an intelligent traceability system. This system identifies, restores history and properties of a product, besides it tracks, in real-time a product. This solution can, also, bring, in the product environment, appropriate adjustments to prevent any risk of threatening qualities for the product. So, it helps supply chain contributors making the sustainable adjustments and the instant benchmark of the supply chain sustainability.

  14. Fluid-bed air-supply system

    DOEpatents

    Atabay, Keramettin

    1979-01-01

    The air-supply system for a fluidized-bed furnace includes two air conduits for the same combustion zone. The conduits feed separate sets of holes in a distributor plate through which fluidizing air flows to reach the bed. During normal operation, only one conduit and set of holes is used, but the second conduit and set of holes is employed during start-up.

  15. The LoTrach system: its role in the prevention of ventilator-associated pneumonia.

    PubMed

    Fletcher, Andrew J W; Ruffell, Alison J; Young, Peter J

    2008-01-01

    To discuss the development of the LoTrach system in light of current evidence around the prevention of ventilator-associated pneumonia (VAP) and its practical application in the intensive care setting. VAP causes substantial morbidity and mortality in ventilated patients in the Intensive Care Unit (ICU), increases length of stay in ICU and is extremely costly. Strategies are needed to reduce the risk of VAP. We examine the need for an endotracheal tube (ETT) specifically designed for the critically-ill patient, the development of the LoTrach system from conception to production, and the role of the various components of the system in preventing VAP. Early issues in implementing this revolutionary equipment into ICU are explored and three case studies highlight advantages of this system. The LoTrach system has been designed to facilitate the provision of a number of evidence-based interventions that have been shown to reduce VAP. Pulmonary aspiration is ubiquitous with conventional cuffs but prevented by the cuff of the LoTrach system when held at a constant and safe pressure against the tracheal wall with a cuff pressure controller. Other aspects incorporated in the ETT are aimed at clearing the secretions from the subglottic space, preventing tube occlusion and accidental extubation, and avoiding damage to the airway. In this way the LoTrach system employs a multifactorial approach to the prevention of VAP and the cost savings from LoTrach rather than a standard ETT will be considerable because of an average 3 day reduction in ICU length of stay related to this. It thus has the potential to be a very useful tool in the ICU setting in the prevention of VAP.

  16. Expert systems for space power supply - Design, analysis, and evaluation

    NASA Technical Reports Server (NTRS)

    Cooper, Ralph S.; Thomson, M. Kemer; Hoshor, Alan

    1987-01-01

    The feasibility of applying expert systems to the conceptual design, analysis, and evaluation of space power supplies in particular, and complex systems in general is evaluated. To do this, the space power supply design process and its associated knowledge base were analyzed and characterized in a form suitable for computer emulation of a human expert. The existing expert system tools and the results achieved with them were evaluated to assess their applicability to power system design. Some new concepts for combining program architectures (modular expert systems and algorithms) with information about the domain were applied to create a 'deep' system for handling the complex design problem. NOVICE, a code to solve a simplified version of a scoping study of a wide variety of power supply types for a broad range of missions, has been developed, programmed, and tested as a concrete feasibility demonstration.

  17. The growing role of noninvasive ventilation in patients requiring prolonged mechanical ventilation.

    PubMed

    Hess, Dean R

    2012-06-01

    For many patients with chronic respiratory failure requiring ventilator support, noninvasive ventilation (NIV) is preferable to invasive support by tracheostomy. Currently available evidence does not support the use of nocturnal NIV in unselected patients with stable COPD. Several European studies have reported benefit for high intensity NIV, in which setting of inspiratory pressure and respiratory rate are selected to achieve normocapnia. There have also been studies reporting benefit for the use of NIV as an adjunct to exercise training. NIV may be useful as an adjunct to airway clearance techniques in patients with cystic fibrosis. Accumulating evidence supports the use of NIV in patients with obesity hypoventilation syndrome. There is considerable observational evidence supporting the use of NIV in patients with chronic respiratory failure related to neuromuscular disease, and one randomized controlled trial reported that the use of NIV was life-prolonging in patients with amyotrophic lateral sclerosis. A variety of interfaces can be used to provide NIV in patients with stable chronic respiratory failure. The mouthpiece is an interface that is unique in this patient population, and has been used with success in patients with neuromuscular disease. Bi-level pressure ventilators are commonly used for NIV, although there are now a new generation of intermediate ventilators that are portable, have a long battery life, and can be used for NIV and invasive applications. Pressure support ventilation, pressure controlled ventilation, and volume controlled ventilation have been used successfully for chronic applications of NIV. New modes have recently become available, but their benefits await evidence to support their widespread use. The success of NIV in a given patient population depends on selection of an appropriate patient, selection of an appropriate interface, selection of an appropriate ventilator and ventilator settings, the skills of the clinician, the

  18. Natural ventilation for the prevention of airborne contagion.

    PubMed

    Escombe, A Roderick; Oeser, Clarissa C; Gilman, Robert H; Navincopa, Marcos; Ticona, Eduardo; Pan, William; Martínez, Carlos; Chacaltana, Jesus; Rodríguez, Richard; Moore, David A J; Friedland, Jon S; Evans, Carlton A

    2007-02-01

    24 h of exposure to untreated TB patients of infectiousness characterised in a well-documented outbreak. This infection rate compared with 33% in modern and 11% in pre-1950 naturally ventilated facilities with windows and doors open. Opening windows and doors maximises natural ventilation so that the risk of airborne contagion is much lower than with costly, maintenance-requiring mechanical ventilation systems. Old-fashioned clinical areas with high ceilings and large windows provide greatest protection. Natural ventilation costs little and is maintenance free, and is particularly suited to limited-resource settings and tropical climates, where the burden of TB and institutional TB transmission is highest. In settings where respiratory isolation is difficult and climate permits, windows and doors should be opened to reduce the risk of airborne contagion.

  19. 46 CFR 111.33-9 - Ventilation exhaust.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... REQUIREMENTS Power Semiconductor Rectifier Systems § 111.33-9 Ventilation exhaust. The exhaust of each forced-air semiconductor rectifier system must: (a) Terminate in a location other than a hazardous location...

  20. Development of Air Supply System for Gas Turbine Combustor Test Rig

    NASA Astrophysics Data System (ADS)

    Kamarudin, Norhaimi Izlan; Hanafi, Muhammad; Mantari, Asril Rajo; Jaafar, Mohammad Nazri Mohd

    2010-06-01

    Complete combustion process occurs when the air and fuel burns at their stoichiometric ratio, which determines the appropriate amount of air needed to be supplied to the combustion chamber. Thus, designing an appropriate air supply system is important, especially for multi-fuel combustion. Each type of fuel has different molecular properties and structures which influence the stoichiometric ratio. Therefore, the designed air supply system must be operable for different types of fuels. Basically, the design of the air supply system is at atmospheric pressure. It is important that the air which enters the combustion chamber is stable and straight. From the calculation, the maximum required mass flow rate of air is 0.1468kg/s.

  1. Characteristics of rain penetration through a gravity ventilator used for natural ventilation.

    PubMed

    Kim, Taehyeung; Lee, Dong Ho; Ahn, Kwangseog; Ha, Hyunchul; Park, Heechang; Piao, Cheng Xu; Li, Xiaoyu; Seo, Jeoungyoon

    2008-01-01

    Gravity ventilators rely simply on air buoyancy to extract air and are widely used to exhaust air contaminants and heat from workplaces using minimal energy. They are designed to maximize the exhaust flow rate, but the rain penetration sometimes causes malfunctioning. In this study, the characteristics of rain penetration through a ventilator were examined as a preliminary study to develop a ventilator with the maximum exhaust capacity while minimizing rain penetration. A model ventilator was built and exposed to artificial rain and wind. The paths, intensities and amounts of penetration through the ventilator were observed and measured in qualitative and quantitative fashions. In the first phase, the pathways and intensities of rain penetration were visually observed. In the second phase, the amounts of rain penetration were quantitatively measured under the different configurations of ventilator components that were installed based on the information obtained in the first-phase experiment. The effects of wind speed, grill direction, rain drainage width, outer wall height, neck height and leaning angle of the outer wall from the vertical position were analyzed. Wind speed significantly affected rain penetration. Under the low crosswind conditions, the rain penetration intensities were under the limit of detection. Under the high crosswind conditions, grill direction and neck height were the most significant factors in reducing rain penetration. The installation of rain drainage was also important in reducing rain penetration. The experimental results suggest that, with proper configurations of its components, a gravity ventilator can be used for natural ventilation without significant rain penetration problems.

  2. A multitracer system for multizone ventilation measurement

    NASA Astrophysics Data System (ADS)

    Sherman, Max

    1990-09-01

    Mass transfer due to pressure-driven air flow is one of the most important processes for determining both environmental quality and energy requirements in buildings. Heat, moisture, and contaminants are all transported by air movement between indoors and outdoors as well as between different zones within a building. Measurement of these air flows is critical to understanding the performance of buildings. Virtually all measurements of ventilation are made using the dilution of a tracer gas. The vast majority of such measurements have been made in a single zone, using a single tracer gas. For the past several years LBL has been developing the MultiTracer Measurement System (MTMS) to provide full multizone air flow information in an accurate, real-time manner. MTMS is based on a quadrupole mass spectrometer to provide high-speed concentration analysis of multiple tracer gases in the (low) ppm level that are injected into multiple zones using mass-flow controllers. The measurement and injection system is controlled by a PC and can measure all concentrations in all zones (and adjust the injected tracer flows) within 2 min and can operate unattended for weeks. The resulting injection rate and concentration data can be analyzed to infer the bulk air movement between zones. The system also measures related quantities such as weather and zonal temperature to assist in the data interpretation. Using MTMS, field measurements have been made for the past two years.

  3. Analysis of hybrid interface cooling system using air ventilation and nanofluid

    NASA Astrophysics Data System (ADS)

    Rani, M. F. H.; Razlan, Z. M.; Bakar, S. A.; Desa, H.; Wan, W. K.; Ibrahim, I.; Kamarrudin, N. S.; Bin-Abdun, Nazih A.

    2017-09-01

    The hybrid interface cooling system needs to be designed for maintaining the electric vehicle's battery cell temperature at 25°C. The hybrid interface cooling system is a combination of two individual systems, where the primary cooling system (R-134a) and the secondary cooling system (CuO + Water) will be used to absorb the heat generated by the battery cells. The ventilation system is designed using air as the medium to transfer the heat from the batteries to the refrigeration system (R-134a). Research will focus on determining the suitable compressor displacement, the heat exchanger volume and the expansion valve resistance value. The analysis for the secondary cooling system is focused on the cooling coil where low temperature nanofluid is passing through each interval of the battery cells. For analysing purposes, the thermal properties of the mixture of 50 grams, Copper (II) Oxide and the base fluid have been determined. The hybrid interface cooling system are able to achieve 57.82% increments in term of rate of heat transfer as compared to the individual refrigeration system.

  4. [Comparison of different types automatic water-supply system for mouse rearing (author's transl)].

    PubMed

    Kikuchi, S; Suzuki, M; Tagashira, Y

    1979-04-01

    Rearing and breeding scores were compared between groups of mice (JCL : ICR and ddN strains) raised with two different types of automatic water-supply systems; the Japanese type and the American type, using manual water-supply system as control. The mice raised with the manual water-supply system were superior in body weight gain as compared to those with two automatic water-supply systems. As to the survival rate, however, the m; anual water-supply system and the Japanese type gave better results than the American type. As to weanling rate in the breeding test, the manual water-supply system gave somewhat better result than either of the two automatic types. Accidental water leaks, which are serious problems of automatic systems, occurred frequently only when the American type was used. Only one defect of the Japanese type revealed was that it was unfavorable for mice with smaller size (e.g., young ddN mice), resulting in lower body weight gain as well as lower breeding scores.

  5. Ultracapacitor-Based Uninterrupted Power Supply System

    NASA Technical Reports Server (NTRS)

    Eichenberg, Dennis J.

    2011-01-01

    The ultracapacitor-based uninterrupted power supply (UPS) system enhances system reliability; reduces life-of-system, maintenance, and downtime costs; and greatly reduces environmental impact when compared to conventional UPS energy storage systems. This design provides power when required and absorbs power when required to smooth the system load and also has excellent low-temperature performance. The UPS used during hardware tests at Glenn is an efficient, compact, maintenance-free, rack-mount, pure sine-wave inverter unit. The UPS provides a continuous output power up to 1,700 W with a surge rating of 1,870 W for up to one minute at a nominal output voltage of 115 VAC. The ultracapacitor energy storage system tested in conjunction with the UPS is rated at 5.8 F. This is a bank of ten symmetric ultracapacitor modules. Each module is actively balanced using a linear voltage balancing technique in which the cell-to-cell leakage is dependent upon the imbalance of the individual cells. The ultracapacitors are charged by a DC power supply, which can provide up to 300 VDC at 4 A. A constant-voltage, constant-current power supply was selected for this application. The long life of ultracapacitors greatly enhances system reliability, which is significant in critical applications such as medical power systems and space power systems. The energy storage system can usually last longer than the application, given its 20-year life span. This means that the ultracapacitors will probably never need to be replaced and disposed of, whereas batteries require frequent replacement and disposal. The charge-discharge efficiency of rechargeable batteries is approximately 50 percent, and after some hundreds of charges and discharges, they must be replaced. The charge-discharge efficiency of ultracapacitors exceeds 90 percent, and can accept more than a million charges and discharges. Thus, there is a significant energy savings through the efficiency improvement, and there is far less

  6. Shuttle cryogenic supply system optimization study. Volume 1: Management supply, sections 1 - 3

    NASA Technical Reports Server (NTRS)

    1973-01-01

    An analysis of the cryogenic supply system for use on space shuttle vehicles was conducted. The major outputs of the analysis are: (1) evaluations of subsystem and integrated system concepts, (2) selection of representative designs, (3) parametric data and sensitivity studies, (4) evaluation of cryogenic cooling in environmental control subsystems, and (5) development of mathematical model.

  7. Noninvasive Ventilation in Premature Neonates.

    PubMed

    Flanagan, Keri Ann

    2016-04-01

    The use of noninvasive ventilation is a constantly evolving treatment option for respiratory disease in the premature infant. The goals of these noninvasive ventilation techniques are to improve gas exchange in the premature infant's lungs and to minimize the need for intubation and invasive mechanical ventilation. The goals of this article are to consider various uses of nasal interfaces, discuss skin care and developmental positioning concerns faced by the bedside nurse, and discuss the medical management aimed to reduce morbidity and mortality. This article explores the nursing role, the advances in medical strategies for noninvasive ventilation, and the team approach to noninvasive ventilation use in this population. Search strategy included a literature review on medical databases, such as EBSCOhost, CINAHL, PubMed, and NeoReviews. Innovative products, nursing research on developmental positioning and skin care, and advanced medical management have led to better and safer outcomes for premature infants requiring noninvasive ventilation. The medical focus of avoiding long-term mechanical ventilation would not be possible without the technology to provide noninvasive ventilation to these premature infants and the watchful eye of the nurse in terms of careful positioning, preventing skin breakdown and facial scarring, and a proper seal to maximize ventilation accuracy. This article encourages nursing-based research to quantify some of the knowledge about skin care and positioning as well as research into most appropriate uses for noninvasive ventilation devices.

  8. Comparison of 4-Dimensional Computed Tomography Ventilation With Nuclear Medicine Ventilation-Perfusion Imaging: A Clinical Validation Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vinogradskiy, Yevgeniy, E-mail: yevgeniy.vinogradskiy@ucdenver.edu; Koo, Phillip J.; Castillo, Richard

    Purpose: Four-dimensional computed tomography (4DCT) ventilation imaging provides lung function information for lung cancer patients undergoing radiation therapy. Before 4DCT-ventilation can be implemented clinically it needs to be validated against an established imaging modality. The purpose of this work was to compare 4DCT-ventilation to nuclear medicine ventilation, using clinically relevant global metrics and radiologist observations. Methods and Materials: Fifteen lung cancer patients with 16 sets of 4DCT and nuclear medicine ventilation-perfusion (VQ) images were used for the study. The VQ-ventilation images were acquired in planar mode using Tc-99m-labeled diethylenetriamine-pentaacetic acid aerosol inhalation. 4DCT data, spatial registration, and a density-change-based modelmore » were used to compute a 4DCT-based ventilation map for each patient. The percent ventilation was calculated in each lung and each lung third for both the 4DCT and VQ-ventilation scans. A nuclear medicine radiologist assessed the VQ and 4DCT scans for the presence of ventilation defects. The VQ and 4DCT-based images were compared using regional percent ventilation and radiologist clinical observations. Results: Individual patient examples demonstrate good qualitative agreement between the 4DCT and VQ-ventilation scans. The correlation coefficients were 0.68 and 0.45, using the percent ventilation in each individual lung and lung third, respectively. Using radiologist-noted presence of ventilation defects and receiver operating characteristic analysis, the sensitivity, specificity, and accuracy of the 4DCT-ventilation were 90%, 64%, and 81%, respectively. Conclusions: The current work compared 4DCT with VQ-based ventilation using clinically relevant global metrics and radiologist observations. We found good agreement between the radiologist's assessment of the 4DCT and VQ-ventilation images as well as the percent ventilation in each lung. The agreement lessened when the data were

  9. Evaluation of Fractional Regional Ventilation Using 4D-CT and Effects of Breathing Maneuvers on Ventilation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mistry, Nilesh N., E-mail: nmistry@som.umaryland.edu; Diwanji, Tejan; Shi, Xiutao

    2013-11-15

    Purpose: Current implementations of methods based on Hounsfield units to evaluate regional lung ventilation do not directly incorporate tissue-based mass changes that occur over the respiratory cycle. To overcome this, we developed a 4-dimensional computed tomography (4D-CT)-based technique to evaluate fractional regional ventilation (FRV) that uses an individualized ratio of tidal volume to end-expiratory lung volume for each voxel. We further evaluated the effect of different breathing maneuvers on regional ventilation. The results from this work will help elucidate the relationship between global and regional lung function. Methods and Materials: Eight patients underwent 3 sets of 4D-CT scans during 1more » session using free-breathing, audiovisual guidance, and active breathing control. FRV was estimated using a density-based algorithm with mass correction. Internal validation between global and regional ventilation was performed by use of the imaging data collected during the use of active breathing control. The impact of breathing maneuvers on FRV was evaluated comparing the tidal volume from 3 breathing methods. Results: Internal validation through comparison between the global and regional changes in ventilation revealed a strong linear correlation (slope of 1.01, R{sup 2} of 0.97) between the measured global lung volume and the regional lung volume calculated by use of the “mass corrected” FRV. A linear relationship was established between the tidal volume measured with the automated breathing control system and FRV based on 4D-CT imaging. Consistently larger breathing volumes were observed when coached breathing techniques were used. Conclusions: The technique presented improves density-based evaluation of lung ventilation and establishes a link between global and regional lung ventilation volumes. Furthermore, the results obtained are comparable with those of other techniques of functional evaluation such as spirometry and hyperpolarized

  10. Mechanical ventilator - infants

    MedlinePlus

    ... this page: //medlineplus.gov/ency/article/007240.htm Mechanical ventilator - infants To use the sharing features on this page, please enable JavaScript. A mechanical ventilator is a machine that assists with breathing. ...

  11. Teleoperated control system for underground room and pillar mining

    DOEpatents

    Mayercheck, William D.; Kwitowski, August J.; Brautigam, Albert L.; Mueller, Brian K.

    1992-01-01

    A teleoperated mining system is provided for remotely controlling the various machines involved with thin seam mining. A thin seam continuous miner located at a mining face includes a camera mounted thereon and a slave computer for controlling the miner and the camera. A plurality of sensors for relaying information about the miner and the face to the slave computer. A slave computer controlled ventilation sub-system which removes combustible material from the mining face. A haulage sub-system removes material mined by the continuous miner from the mining face to a collection site and is also controlled by the slave computer. A base station, which controls the supply of power and water to the continuous miner, haulage system, and ventilation systems, includes cable/hose handling module for winding or unwinding cables/hoses connected to the miner, an operator control module, and a hydraulic power and air compressor module for supplying air to the miner. An operator controlled host computer housed in the operator control module is connected to the slave computer via a two wire communications line.

  12. Liquid ventilation.

    PubMed

    Sarkar, Suman; Paswan, Anil; Prakas, S

    2014-01-01

    Human have lungs to breathe air and they have no gills to breath liquids like fish. When the surface tension at the air-liquid interface of the lung increases as in acute lung injury, scientists started to think about filling the lung with fluid instead of air to reduce the surface tension and facilitate ventilation. Liquid ventilation (LV) is a technique of mechanical ventilation in which the lungs are insufflated with an oxygenated perfluorochemical liquid rather than an oxygen-containing gas mixture. The use of perfluorochemicals, rather than nitrogen as the inert carrier of oxygen and carbon dioxide offers a number of advantages for the treatment of acute lung injury. In addition, there are non-respiratory applications with expanding potential including pulmonary drug delivery and radiographic imaging. It is well-known that respiratory diseases are one of the most common causes of morbidity and mortality in intensive care unit. During the past few years several new modalities of treatment have been introduced. One of them and probably the most fascinating, is of LV. Partial LV, on which much of the existing research has concentrated, requires partial filling of lungs with perfluorocarbons (PFC's) and ventilation with gas tidal volumes using conventional mechanical ventilators. Various physico-chemical properties of PFC's make them the ideal media. It results in a dramatic improvement in lung compliance and oxygenation and decline in mean airway pressure and oxygen requirements. No long-term side-effect reported.

  13. Transition from in-hospital ventilation to home ventilation: process description and quality indicators

    PubMed Central

    Kastrup, Marc; Tittmann, Benjamin; Sawatzki, Tanja; Gersch, Martin; Vogt, Charlotte; Rosenthal, Max; Rosseau, Simone; Spies, Claudia

    2017-01-01

    The current demographic development of our society results in an increasing number of elderly patients with chronic diseases being treated in the intensive care unit. A possible long-term consequence of such a treatment is that patients remain dependent on certain invasive organ support systems, such as long-term ventilator dependency. The main goal of this project is to define the transition process between in-hospital and out of hospital (ambulatory) ventilator support. A further goal is to identify evidence-based quality indicators to help define and describe this process. This project describes an ideal sequence of processes (process chain), based on the current evidence from the literature. Besides the process chain, key data and quality indicators were described in detail. Due to the limited project timeline, these indicators were not extensively tested in the clinical environment. The results of this project may serve as a solid basis for proof of feasibility and proof of concept investigations, optimize the transition process of ventilator-dependent patients from a clinical to an ambulatory setting, as well as reduce the rate of emergency re-admissions. PMID:29308061

  14. Exploration Mission Particulate Matter Filtration Technology Performance Testing in a Simulated Spacecraft Cabin Ventilation System

    NASA Technical Reports Server (NTRS)

    Agui, Juan H.; Vijayakumar, R.; Perry, Jay L.; Frederick, Kenneth R.; Mccormick, Robert M.

    2017-01-01

    Human deep space exploration missions will require advances in long-life, low maintenance airborne particulate matter filtration technology. As one of the National Aeronautics and Space Administrations (NASA) developments in this area, a prototype of a new regenerable, multi-stage particulate matter filtration technology was tested in an International Space Station (ISS) module simulation facility. As previously reported, the key features of the filter system include inertial and media filtration with regeneration and in-place media replacement techniques. The testing facility can simulate aspects of the cabin environment aboard the ISS and contains flight-like cabin ventilation system components. The filtration technology test article was installed at the inlet of the central ventilation system duct and instrumented to provide performance data under nominal flow conditions. In-place regeneration operations were also evaluated. The real-time data included pressure drop across the filter stages, process air flow rate, ambient pressure, humidity and temperature. In addition, two video cameras positioned at the filtration technology test articles inlet and outlet were used to capture the mechanical performance of the filter media indexing operation under varying air flow rates. Recent test results are presented and future design recommendations are discussed.

  15. Hygiene guideline for the planning, installation, and operation of ventilation and air-conditioning systems in health-care settings - Guideline of the German Society for Hospital Hygiene (DGKH).

    PubMed

    Külpmann, Rüdiger; Christiansen, Bärbel; Kramer, Axel; Lüderitz, Peter; Pitten, Frank-Albert; Wille, Frank; Zastrow, Klaus-Dieter; Lemm, Friederike; Sommer, Regina; Halabi, Milo

    2016-01-01

    Since the publication of the first "Hospital Hygiene Guideline for the implementation and operation of air conditioning systems (HVAC systems) in hospitals" (http://www.krankenhaushygiene.de/informationen/fachinformationen/leitlinien/12) in 2002, it was necessary due to the increase in knowledge, new regulations, improved air-conditioning systems and advanced test methods to revise the guideline. Based on the description of the basic features of ventilation concepts, its hygienic test and the usage-based requirements for ventilation, the DGKH section "Ventilation and air conditioning technology" attempts to provide answers for the major air quality issues in the planning, design and the hygienically safe operation of HVAC systems in rooms of health care.

  16. Ventilation through a small-bore catheter: optimizing expiratory ventilation assistance.

    PubMed

    Hamaekers, A E W; Borg, P A J; Götz, T; Enk, D

    2011-03-01

    Emergency ventilation through a small-bore transtracheal catheter can be lifesaving in a 'cannot intubate, cannot ventilate' situation. Ejectors, capable of creating suction by the Bernoulli principle, have been proposed to facilitate expiration through small-bore catheters. In this bench study, we compared a novel, purpose-built ventilation ejector (DE 5) with a previously proposed, modified industrial ejector (SBP 07). The generated insufflation pressures, suction pressures in static and dynamic situations, and also suction capacities and entrainment ratios of the SBP 07 and the DE 5 were determined. The DE 5 was also tested in a lung simulator with a simulated complete upper airway obstruction. Inspiratory and expiratory times through a transtracheal catheter were measured at various flow rates and achievable minute volumes were calculated. In a static situation, the SBP 07 showed a more negative pressure build-up compared with the DE 5. However, in a dynamic situation, the DE 5 generated a more negative pressure, resulting in a higher suction capacity. Employment of the DE 5 at a flow rate of 18 litre min(-1) allowed a minute volume through the transtracheal catheter of up to 8.27 litre min(-1) at a compliance of 100 ml cm H(2)O(-1). The efficiency of the DE 5 depended on the flow rate of the driving gas and the compliance of the lung simulator. In laboratory tests, the DE 5 is an optimized ventilation ejector suitable for applying expiratory ventilation assistance. Further research may confirm the clinical applicability as a portable emergency ventilator for use with small-bore catheters.

  17. High resolution pCO2 monitoring reveals ventilation of Bunker Cave (NW Germany) and its impact on speleothem growth

    NASA Astrophysics Data System (ADS)

    Riechelmann, Sylvia; Breitenbach, Sebastian F. M.; Schröder-Ritzrau, Andrea; Immenhauser, Adrian

    2017-04-01

    presumably higher under natural conditions. Thus, the present-day ventilation system of Bunker Cave is not a direct analogue for natural ventilation conditions. pCO2 concentrations are relatively low compared to other caves, and because the difference between summer and winter pCO2 is relatively low (max. 400 ppm), a significant effect on seasonal speleothem growth rate is unlikely. In case of Bunker Cave, it is rather a combination of the availability of water, and thus of calcium and carbonate ions and pCO2 concentrations that allow higher carbonate precipitation during winter than summer. Holocene speleothems from Bunker Cave display relatively slow growth rates. We suggest that - with absence of major entrances to the cave system during the Holocene - ventilation was minimal and pCO2 concentrations significantly higher, making winterly water supply the governing factor regulating speleothem growth. Thus, stalagmites from Bunker Cave are likely to record a climatic signal biased towards the winter season.

  18. Power supply system for the superconducting outsert of the CHMFL hybrid magnet

    NASA Astrophysics Data System (ADS)

    Fang, Z.; Zhu, J.; Chen, W.; Jiang, D.; Huang, P.; Chen, Z.; Tan, Y.; Kuang, G.

    2017-12-01

    The construction of a new hybrid magnet, consisting of a 11 T superconducting outsert and a 34 T resistive insert magnet, has been finished at the Chinese High Magnetic Field Laboratory (CHMFL) in Hefei. With a room temperature bore of 800 mm in diameter, the hybrid magnet superconducting outsert is composed of four separate Nb3Sn-based Cable-in-Conduit Conductor (CICC) coils electrically connected in series and powered by a single power supply system. The power supply system for the superconducting outsert consists of a 16 kA DC power supply, a quench protection system, a pair of 16 kA High Temperature Superconducting (HTS) current leads, and two Low Temperature Superconducting bus-lines. The design and manufacturing of the power supply system have been completed at the CHMFL. This paper describes the design features of the power supply system as well as the current fabrication condition of its main components.

  19. Measure Guideline: Ventilation Guidance for Residential High-Performance New Construction - Multifamily

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lstiburek, Joseph

    2017-01-01

    The measure guideline provides ventilation guidance for residential high performance multifamily construction that incorporates the requirements of the ASHRAE 62.2 ventilation and indoor air quality standard. The measure guideline focus is on the decision criteria for weighing cost and performance of various ventilation systems. The measure guideline is intended for contractors, builders, developers, designers and building code officials. The guide may also be helpful to building owners wishing to learn more about ventilation strategies available for their buildings. The measure guideline includes specific design and installation instructions for the most cost effective and performance effective solutions for ventilation in multifamilymore » units that satisfies the requirements of ASHRAE 62.2-2016.« less

  20. Measure Guideline: Ventilation Guidance for Residential High-Performance New Construction - Multifamily

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lstiburek, Joseph

    The measure guideline provides ventilation guidance for residential high performance multifamily construction that incorporates the requirements of the ASHRAE 62.2 ventilation and indoor air quality standard. The measure guideline focus is on the decision criteria for weighing cost and performance of various ventilation systems. The measure guideline is intended for contractors, builders, developers, designers and building code officials. The guide may also be helpful to building owners wishing to learn more about ventilation strategies available for their buildings. The measure guideline includes specific design and installation instructions for the most cost effective and performance effective solutions for ventilation in multifamilymore » units that satisfies the requirements of ASHRAE 62.2-2016.« less

  1. Moderate glucose supply reduces hemolysis during systemic inflammation

    PubMed Central

    Jägers, Johannes; Brauckmann, Stephan; Kirsch, Michael; Effenberger-Neidnicht, Katharina

    2018-01-01

    Background Systemic inflammation alters energy metabolism. A sufficient glucose level, however, is most important for erythrocytes, since erythrocytes rely on glucose as sole source of energy. Damage to erythrocytes leads to hemolysis. Both disorders of glucose metabolism and hemolysis are associated with an increased risk of death. The objective of the study was to investigate the impact of intravenous glucose on hemolysis during systemic inflammation. Materials and methods Systemic inflammation was accomplished in male Wistar rats by continuous lipopolysaccharide (LPS) infusion (1 mg LPS/kg and h, 300 min). Sham control group rats received Ringer’s solution. Glucose was supplied moderately (70 mg glucose/kg and h) or excessively (210 mg glucose/kg and h) during systemic inflammation. Vital parameters (eg, systemic blood pressure) as well as blood and plasma parameters (eg, concentrations of glucose, lactate and cell-free hemoglobin, and activity of lactate dehydrogenase) were measured hourly. Clot formation was analyzed by thromboelastometry. Results Continuous infusion of LPS led to a so-called post-aggression syndrome with disturbed electrolyte homeostasis (hypocalcemia, hyperkalemia, and hypernatremia), changes in hemodynamics (tachycardia and hypertension), and a catabolic metabolism (early hyperglycemia, late hypoglycemia, and lactate formation). It induced severe tissue injury (significant increases in plasma concentrations of transaminases and lactate dehydrogenase), alterations in blood coagulation (disturbed clot formation), and massive hemolysis. Both moderate and excessive glucose supply reduced LPS-induced increase in systemic blood pressure. Excessive but not moderate glucose supply increased blood glucose level and enhanced tissue injury. Glucose supply did not reduce LPS-induced alterations in coagulation, but significantly reduced hemolysis induced by LPS. Conclusion Intravenous glucose infusion can diminish LPS-related changes in hemodynamics

  2. Enhancing Safety of Artificially Ventilated Patients Using Ambient Process Analysis.

    PubMed

    Lins, Christian; Gerka, Alexander; Lüpkes, Christian; Röhrig, Rainer; Hein, Andreas

    2018-01-01

    In this paper, we present an approach for enhancing the safety of artificially ventilated patients using ambient process analysis. We propose to use an analysis system consisting of low-cost ambient sensors such as power sensor, RGB-D sensor, passage detector, and matrix infrared temperature sensor to reduce risks for artificially ventilated patients in both home and clinical environments. We describe the system concept and our implementation and show how the system can contribute to patient safety.

  3. Intraoperative mechanical ventilation strategies in patients undergoing one-lung ventilation: a meta-analysis.

    PubMed

    Liu, Zhen; Liu, Xiaowen; Huang, Yuguang; Zhao, Jing

    2016-01-01

    Postoperative pulmonary complications (PPCs), which are not uncommon in one-lung ventilation, are among the main causes of postoperative death after lung surgery. Intra-operative ventilation strategies can influence the incidence of PPCs. High tidal volume (V T) and increased airway pressure may lead to lung injury, while pressure-controlled ventilation and lung-protective strategies with low V T may have protective effects against lung injury. In this meta-analysis, we aim to investigate the effects of different ventilation strategies, including pressure-controlled ventilation (PCV), volume-controlled ventilation (VCV), protective ventilation (PV) and conventional ventilation (CV), on PPCs in patients undergoing one-lung ventilation. We hypothesize that both PV with low V T and PCV have protective effects against PPCs in one-lung ventilation. A systematic search (PubMed, EMBASE, the Cochrane Library, and Ovid MEDLINE; in May 2015) was performed for randomized trials comparing PCV with VCV or comparing PV with CV in one-lung ventilation. Methodological quality was evaluated using the Cochrane tool for risk. The primary outcome was the incidence of PPCs. The secondary outcomes included the length of hospital stay, intraoperative plateau airway pressure (Pplateau), oxygen index (PaO2/FiO2) and mean arterial pressure (MAP). In this meta-analysis, 11 studies (436 patients) comparing PCV with VCV and 11 studies (657 patients) comparing PV with CV were included. Compared to CV, PV decreased the incidence of PPCs (OR 0.29; 95 % CI 0.15-0.57; P < 0.01) and intraoperative Pplateau (MD -3.75; 95 % CI -5.74 to -1.76; P < 0.01) but had no significant influence on the length of hospital stay or MAP. Compared to VCV, PCV decreased intraoperative Pplateau (MD -1.46; 95 % CI -2.54 to -0.34; P = 0.01) but had no significant influence on PPCs, PaO2/FiO2 or MAP. PV with low V T was associated with the reduced incidence of PPCs compared to CV. However, PCV and VCV had similar

  4. Trends in mechanical ventilation: are we ventilating our patients in the best possible way?

    PubMed Central

    Veneroni, Chiara; Farre’, Ramon

    2017-01-01

    This review addresses how the combination of physiology, medicine and engineering principles contributed to the development and advancement of mechanical ventilation, emphasising the most urgent needs for improvement and the most promising directions of future development. Several aspects of mechanical ventilation are introduced, highlighting on one side the importance of interdisciplinary research for further development and, on the other, the importance of training physicians sufficiently on the technological aspects of modern devices to exploit properly the great complexity and potentials of this treatment. Educational aims To learn how mechanical ventilation developed in recent decades and to provide a better understanding of the actual technology and practice. To learn how and why interdisciplinary research and competences are necessary for providing the best ventilation treatment to patients. To understand which are the most relevant technical limitations in modern mechanical ventilators that can affect their performance in delivery of the treatment. To better understand and classify ventilation modes. To learn the classification, benefits, drawbacks and future perspectives of automatic ventilation tailoring algorithms. PMID:28620428

  5. Trends in mechanical ventilation: are we ventilating our patients in the best possible way?

    PubMed

    Dellaca', Raffaele L; Veneroni, Chiara; Farre', Ramon

    2017-06-01

    This review addresses how the combination of physiology, medicine and engineering principles contributed to the development and advancement of mechanical ventilation, emphasising the most urgent needs for improvement and the most promising directions of future development. Several aspects of mechanical ventilation are introduced, highlighting on one side the importance of interdisciplinary research for further development and, on the other, the importance of training physicians sufficiently on the technological aspects of modern devices to exploit properly the great complexity and potentials of this treatment. To learn how mechanical ventilation developed in recent decades and to provide a better understanding of the actual technology and practice.To learn how and why interdisciplinary research and competences are necessary for providing the best ventilation treatment to patients.To understand which are the most relevant technical limitations in modern mechanical ventilators that can affect their performance in delivery of the treatment.To better understand and classify ventilation modes.To learn the classification, benefits, drawbacks and future perspectives of automatic ventilation tailoring algorithms.

  6. Isotopic metrics for structure, connectivity, and residence time in urban water supply systems

    NASA Astrophysics Data System (ADS)

    Bowen, Gabriel; Kennedy, Casey; Good, Stephen; Ehleringer, James

    2014-05-01

    Public water supply systems are the life-blood of urban areas, accessing, managing, and distributing water from an often complex array of sources to provide on-demand access to safe, potable water at the point-of-use. Water managers are faced with a wide range of potential threats, ranging from climate change to infrastructure failure to supply contamination. Information on the structure of supply and conveyance systems, connectivity within these systems, and links between the point-of-use and environmental water sources are thus critical to assessing the stability of water supplies and responding efficiently and effectively to water supply threats. We report datasets documenting stable hydrogen and oxygen isotope ratios of public supply water in cities of the United States across a range of scales. The data show a wide range of spatial and temporal variability that can be attributed to a combination of regional hydroclimate and water supply characteristics. Comparisons of public supply waters with model-based estimates of the isotopic composition of regional water sources suggests that major factors reflected in the tap water data include the degree of fragmentation of natural and man-made storage and conveyance systems, inter-basinal transfer of water, evaporative losses, and the total residence time of the natural and artificial systems being exploited. Because each of these factors contributes to determining the sustainability of water supply systems and their sensitivity to environmental disturbance, we propose a set of isotope-based metrics that can be used to efficiently assess and monitor the characteristics of public-supply systems in water security assessments and in support of management, planning, and outreach activities.

  7. Multiple fuel supply system for an internal combustion engine

    DOEpatents

    Crothers, William T.

    1977-01-01

    A multiple fuel supply or an internal combustion engine wherein phase separation of components is deliberately induced. The resulting separation permits the use of a single fuel tank to supply components of either or both phases to the engine. Specifically, phase separation of a gasoline/methanol blend is induced by the addition of a minor amount of water sufficient to guarantee separation into an upper gasoline phase and a lower methanol/water phase. A single fuel tank holds the two-phase liquid with separate fuel pickups and separate level indicators for each phase. Either gasoline or methanol, or both, can be supplied to the engine as required by predetermined parameters. A fuel supply system for a phase-separated multiple fuel supply contained in a single fuel tank is described.

  8. Measure Guideline: Ventilation Cooling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Springer, D.; Dakin, B.; German, A.

    2012-04-01

    The purpose of this measure guideline on ventilation cooling is to provide information on a cost-effective solution for reducing cooling system energy and demand in homes located in hot-dry and cold-dry climates. This guideline provides a prescriptive approach that outlines qualification criteria, selection considerations, and design and installation procedures.

  9. Selected Bibliographies for Pharmaceutical Supply Systems. Volume 5: Pharmaceutical Supply Systems Bibliographies. International Health Planning Reference Series.

    ERIC Educational Resources Information Center

    Schaumann, Leif

    Intended as a companion piece to volume 7 in the Method Series, Pharmaceutical Supply System Planning (CE 024 234), this fifth of six volumes in the International Health Planning Reference Series is a combined literature review and annotated bibliography dealing with alternative methodologies for planning and analyzing pharmaceutical supply…

  10. Regional Lung Ventilation Analysis Using Temporally Resolved Magnetic Resonance Imaging.

    PubMed

    Kolb, Christoph; Wetscherek, Andreas; Buzan, Maria Teodora; Werner, René; Rank, Christopher M; Kachelrie, Marc; Kreuter, Michael; Dinkel, Julien; Heuel, Claus Peter; Maier-Hein, Klaus

    We propose a computer-aided method for regional ventilation analysis and observation of lung diseases in temporally resolved magnetic resonance imaging (4D MRI). A shape model-based segmentation and registration workflow was used to create an atlas-derived reference system in which regional tissue motion can be quantified and multimodal image data can be compared regionally. Model-based temporal registration of the lung surfaces in 4D MRI data was compared with the registration of 4D computed tomography (CT) images. A ventilation analysis was performed on 4D MR images of patients with lung fibrosis; 4D MR ventilation maps were compared with corresponding diagnostic 3D CT images of the patients and 4D CT maps of subjects without impaired lung function (serving as reference). Comparison between the computed patient-specific 4D MR regional ventilation maps and diagnostic CT images shows good correlation in conspicuous regions. Comparison to 4D CT-derived ventilation maps supports the plausibility of the 4D MR maps. Dynamic MRI-based flow-volume loops and spirograms further visualize the free-breathing behavior. The proposed methods allow for 4D MR-based regional analysis of tissue dynamics and ventilation in spontaneous breathing and comparison of patient data. The proposed atlas-based reference coordinate system provides an automated manner of annotating and comparing multimodal lung image data.

  11. Controlled invasive mechanical ventilation strategies in obese patients undergoing surgery.

    PubMed

    Maia, Lígia de Albuquerque; Silva, Pedro Leme; Pelosi, Paolo; Rocco, Patricia Rieken Macedo

    2017-06-01

    The obesity prevalence is increasing in surgical population. As the number of obese surgical patients increases, so does the demand for mechanical ventilation. Nevertheless, ventilatory strategies in this population are challenging, since obesity results in pathophysiological changes in respiratory function. Areas covered: We reviewed the impact of obesity on respiratory system and the effects of controlled invasive mechanical ventilation strategies in obese patients undergoing surgery. To date, there is no consensus regarding the optimal invasive mechanical ventilation strategy for obese surgical patients, and no evidence that possible intraoperative beneficial effects on oxygenation and mechanics translate into better postoperative pulmonary function or improved outcomes. Expert commentary: Before determining the ideal intraoperative ventilation strategy, it is important to analyze the pathophysiology and comorbidities of each obese patient. Protective ventilation with low tidal volume, driving pressure, energy, and mechanical power should be employed during surgery; however, further studies are required to clarify the most effective ventilation strategies, such as the optimal positive end-expiratory pressure and whether recruitment maneuvers minimize lung injury. In this context, an ongoing trial of intraoperative ventilation in obese patients (PROBESE) should help determine the mechanical ventilation strategy that best improves clinical outcome in patients with body mass index≥35kg/m 2 .

  12. Study on the Enhanced Operation of Self-Ventilation-Based Coupling System for Domestic Wastewater Treatment

    NASA Astrophysics Data System (ADS)

    Kong, Lingwei; Wang, Lu; Zhang, Yi; Mei, Rongwu; Zhang, Yu

    2018-06-01

    In this study, a new coupling system of biological filter bed and subsurface-flow constructed wetland based on the self-ventilation network was proposed, and the comparative pollutant removal efficiency at low and high influent concentration of the pilot coupling system with different substrates configurations were investigated. The study found that: The comparison system (b) had better removal rates than that of the original system (a), and the removal rate when treating low influent concentration was 74.10%, 94.14%, 73.57% and 69.53%, while in high influent concentration case was 81.30%, 90.28%, 88.57% and 75.36% for CODCr , NH4+ -N, TN and TP, respectively. The removal of the above main water indexes of the comparison system (b) promoted by 11.00%, 11.55%, 2.69% and 8.09% respectively in low influent concentration case and 4.20%, 9.20%, 7.66% and 13.61% respectively in high influent concentration case when comparing to the original system (a), which showed that the optimized configuration of various kinds of substrates was significant and was more beneficial to the degradation and removal of pollutants. The adsorption and interception function of substrates in the constructed wetland was the main way of phosphorus removal. The function of self-ventilation ensured the amount of DO in the coupling system, making the phosphorus removal was less affected comparing to structure of traditional wetland.

  13. System redesign of the immunization supply chain: Experiences from Benin and Mozambique.

    PubMed

    Prosser, Wendy; Jaillard, Philippe; Assy, Emmanuelle; Brown, Shawn T; Matsinhe, Graça; Dekoun, Mawutondji; Lee, Bruce Y

    2017-04-19

    Evidence suggests that immunization supply chains are becoming outdated and unable to deliver needed vaccines due to growing populations and new vaccine introductions. Redesigning a supply chain could result in meeting current demands. The Ministries of Health in Benin in Mozambique recognized known barriers to the immunization supply chain and undertook a system redesign to address those barriers. Changes were made to introduce an informed push system while consolidating storage points, introducing transport loops, and increasing human resource capacity for distribution. Evaluations were completed in each country. Evaluation in each country indicated improved performance of the supply chain. The Effective Vaccine Management (EVM) assessment in Benin documented notable improvements in the distribution criteria of the tool, increasing from 40% to 100% at the district level. In Mozambique, results showed reduced stockouts at health facility level from 79% at baseline to less than 1% at endline. Coverage rates of DTP3 also increased from 68.9% to 92.8%. Benin and Mozambique are undertaking system redesign in order to respond to constraints identified in the vaccine supply chain. Results and learnings show improvements in supply chain performance and make a strong case for system redesign. These countries demonstrate the feasibility of system redesign for other countries considering how to address outdated supply chains. Copyright © 2017 The Author(s). Published by Elsevier Ltd.. All rights reserved.

  14. Weaning from mechanical ventilation: why are we still looking for alternative methods?

    PubMed

    Frutos-Vivar, F; Esteban, A

    2013-12-01

    Most patients who require mechanical ventilation for longer than 24 hours, and who improve the condition leading to the indication of ventilatory support, can be weaned after passing a first spontaneous breathing test. The challenge is to improve the weaning of patients who fail that first test. We have methods that can be referred to as traditional, such as the T-tube, pressure support or synchronized intermittent mandatory ventilation (SIMV). In recent years, however, new applications of usual techniques as noninvasive ventilation, new ventilation methods such as automatic tube compensation (ATC), mandatory minute ventilation (MMV), adaptive support ventilation or automatic weaning systems based on pressure support have been described. Their possible role in weaning from mechanical ventilation among patients with difficult or prolonged weaning remains to be established. Copyright © 2012 Elsevier España, S.L. and SEMICYUC. All rights reserved.

  15. 30 CFR 75.1107-8 - Fire suppression devices; extinguishant supply systems.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Fire suppression devices; extinguishant supply systems. (a) Fire suppression systems using water or... equivalent protective devices and a rising stem or other visual indicator-type shutoff valve. (b) Water supplies for fire suppression devices installed on underground equipment may be maintained in mounted water...

  16. 30 CFR 75.1107-8 - Fire suppression devices; extinguishant supply systems.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Fire suppression devices; extinguishant supply systems. (a) Fire suppression systems using water or... equivalent protective devices and a rising stem or other visual indicator-type shutoff valve. (b) Water supplies for fire suppression devices installed on underground equipment may be maintained in mounted water...

  17. 30 CFR 75.1107-8 - Fire suppression devices; extinguishant supply systems.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Fire suppression devices; extinguishant supply systems. (a) Fire suppression systems using water or... equivalent protective devices and a rising stem or other visual indicator-type shutoff valve. (b) Water supplies for fire suppression devices installed on underground equipment may be maintained in mounted water...

  18. High-Frequency Percussive Ventilation Revisited

    DTIC Science & Technology

    2010-01-01

    be implemented. ‡ Follow the reverse of the ventilation sequence if respiratory alkalosis develops—however, start at ventilation goal sequence 1 not at...High-frequency percussive ventilation (HFPV) has demonstrated a potential role as a rescue option for refractory acute respiratory distress syndrome...frequency percussive ventilation (HFPV) has demon- strated a potential role as a salvage option for refrac- tory acute respiratory distress syndrome

  19. Lung deposition and systemic bioavailability of different aerosol devices with and without humidification in mechanically ventilated patients.

    PubMed

    Moustafa, Islam O F; Ali, Mohammed R A-A; Al Hallag, Moataz; Rabea, Hoda; Fink, James B; Dailey, Patricia; Abdelrahim, Mohamed E A

    During mechanical ventilation medical aerosol delivery has been reported to be upto two fold greater with dry inhaled gas than with heated humidity. Urine levels at 0.5 h post dose (URSAL0.5%) has been confirmed as an index of lung deposition and 24 h (URSAL24%) as index of systemic absorption. Our aim was to determine the effect of humidification and aerosol device type on drug delivery to ventilated patients using urine levels. In a randomized crossover design, 36 (18female) mechanically ventilated patients were assigned to one of three groups. Groups 1 and 2 received 5000 μg salbutamol using vibrating mesh (VM) and jet nebulizers (JN), respectively, while group 3 received 1600 μg (16 puffs) of salbutamol via metered dose inhaler with AeroChamber Vent (MDI-AV). All devices were placed in the inspiratory limb of ventilator downstream from the humidifier. Each subject received aerosol with and without humidity at >24 h intervals with >12 h washout periods between salbutamol doses. Patients voided urine 15 min before each study dose and urine samples were collected at 0.5 h post dosing and pooled for the next 24 h. The MDI-AV and VM resulted in a higher percentage of urinary salbutamol levels compared to the JN (p < 0.05). Urine levels were similar between humidity and dry conditions. Our findings suggest that in-vitro reports overestimate the impact of dry vs. heated humidified conditions on the delivery of aerosol during invasive mechanical ventilation. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. International Space Station USOS Crew Quarters Ventilation and Acoustic Design Implementation

    NASA Technical Reports Server (NTRS)

    Broyan, James Lee, Jr.

    2009-01-01

    The International Space Station (ISS) United States Operational Segment (USOS) has four permanent rack sized ISS Crew Quarters (CQ) providing a private crewmember space. The CQ uses Node 2 cabin air for ventilation/thermal cooling, as opposed to conditioned ducted air from the ISS Temperature Humidity Control System or the ISS fluid cooling loop connections. Consequently, CQ can only increase the air flow rate to reduce the temperature delta between the cabin and the CQ interior. However, increasing airflow causes increased acoustic noise so efficient airflow distribution is an important design parameter. The CQ utilized a two fan push-pull configuration to ensure fresh air at the crewmember s head position and reduce acoustic exposure. The CQ interior needs to be below Noise Curve 40 (NC-40). The CQ ventilation ducts are open to the significantly louder Node 2 cabin aisle way which required significantly acoustic mitigation controls. The design implementation of the CQ ventilation system and acoustic mitigation are very inter-related and require consideration of crew comfort balanced with use of interior habitable volume, accommodation of fan failures, and possible crew uses that impact ventilation and acoustic performance. This paper illustrates the types of model analysis, assumptions, vehicle interactions, and trade-offs required for CQ ventilation and acoustics. Additionally, on-orbit ventilation system performance and initial crew feedback is presented. This approach is applicable to any private enclosed space that the crew will occupy.

  1. Cooling System to Treat Exercise-Induced Hyperthermia

    DTIC Science & Technology

    2016-06-01

    temperatures . Additionally, individual variations in sweat rates, ventilation rates, fitness levels, and oxygen consumption were not...gastrointestinal MHR maximum heart rate NASA National Aeronautics and Space Administration Tc core temperature UCHS uncompensated heat stress VO2peak peak oxygen consumption ...the effectiveness of a cooling pump based patient thermal management system supplied by Aspen Systems on lowering core body temperature

  2. POWER SUPPLY CONTROL AND MONITORING FOR THE SNS RING AND TRANSPORT SYSTEM

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    LAMBIASE,R.; OERTER,B.; PENG,S.

    2001-06-28

    There are approximately 300 magnet power supplies in the SNS accumulator ring and transport lines. Control and monitoring of the these converters will be primarily accomplished with a new Power Supply Interface and Controller (PSI/PSC) system developed for the SNS project. This PSI/PSC system provides all analog and digital commands and status readbacks in one fiber isolated module. With a maximum rate of 10KHz, the PSI/PSC must be supplemented with higher speed systems for the wide bandwidth pulsed injection supplies, and the even wider bandwidth extraction kickers. This paper describes the implementation of this PSI/PSC system, which was developed throughmore » an industry/laboratory collaboration, and the supplementary equipment used to support the wider bandwidth pulsed supplies.« less

  3. High tidal volume ventilation in infant mice.

    PubMed

    Cannizzaro, Vincenzo; Zosky, Graeme R; Hantos, Zoltán; Turner, Debra J; Sly, Peter D

    2008-06-30

    Infant mice were ventilated with either high tidal volume (V(T)) with zero end-expiratory pressure (HVZ), high V(T) with positive end-expiratory pressure (PEEP) (HVP), or low V(T) with PEEP. Thoracic gas volume (TGV) was determined plethysmographically and low-frequency forced oscillations were used to measure the input impedance of the respiratory system. Inflammatory cells, total protein, and cytokines in bronchoalveolar lavage fluid (BALF) and interleukin-6 (IL-6) in serum were measured as markers of pulmonary and systemic inflammatory response, respectively. Coefficients of tissue damping and tissue elastance increased in all ventilated mice, with the largest rise seen in the HVZ group where TGV rapidly decreased. BALF protein levels increased in the HVP group, whereas serum IL-6 rose in the HVZ group. PEEP keeps the lungs open, but provides high volumes to the entire lungs and induces lung injury. Compared to studies in adult and non-neonatal rodents, infant mice demonstrate a different response to similar ventilation strategies underscoring the need for age-specific animal models.

  4. Conducting Sanitary Surveys of Water Supply Systems. Student Workbook.

    ERIC Educational Resources Information Center

    1976

    This workbook is utilized in connection with a 40-hour course on sanitary surveys of water supply systems for biologists, chemists, and engineers with experience as a water supply evaluator. Practical training is provided in each of the 21 self-contained modules. Each module outlines the purpose, objectives and content for that section. The course…

  5. Impact of different supply air and recirculating air filtration systems on stable climate, animal health, and performance of fattening pigs in a commercial pig farm

    PubMed Central

    Wenke, Cindy; Pospiech, Janina; Reutter, Tobias; Altmann, Bettina; Truyen, Uwe

    2018-01-01

    Biosecurity is defined as the implementation of measures that reduce the risk of disease agents being introduced and/or spread. For pig production, several of these measures are routinely implemented (e.g. cleaning, disinfection, segregation). However, air as a potential vector of pathogens has long been disregarded. Filters for incoming and recirculating air were installed into an already existing ventilation plant at a fattening piggery (3,840 pigs at maximum) in Saxony, Germany. Over a period of three consecutive fattening periods, we evaluated various parameters including air quality indices, environmental and operating parameters, and pig performance. Animal data regarding respiratory diseases, presence of antibodies against influenza A viruses, PRRSV, and Actinobacillus pleuropneumoniae and lung health score at slaughter were recorded, additionally. There were no significant differences (p = 0.824) in total bacterial counts between barns with and without air filtration. Recirculating air filtration resulted in the lowest total dust concentration (0.12 mg/m3) and lung health was best in animals from the barn equipped with recirculating air filtration modules. However, there was no difference in animal performance. Antibodies against all above mentioned pathogens were detected but mostly animals were already antibody-positive at re-stocking. We demonstrated that supply air filtration as well as recirculating air filtration technique can easily be implemented in an already existing ventilation system and that recirculating air filtration resulted in enhanced lung health compared to supply air-filtered and non-filtered barns. A more prominent effect might have been obtained in a breeding facility because of the longer life span of sows and a higher biosecurity level with air filtration as an add-on measure. PMID:29558482

  6. Ligncellulosic feedstock supply systems with intermodal and overseas transportation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ric Hoefnagels; Kara Cafferty; Erin Searcy

    2014-12-01

    With growing demand for biomass from industrial uses and international trade, the logistic operations required to economically move the biomass from the field or forest to the end users have become increasingly complex. In addition to economics, understanding energy and GHG emissions is required to design cost effective, sustainable logistic process operations; in order to improve international supply chains it is also important to understate their interdependencies and related uncertainties. This article presents an approach to assess lignocellulosic feedstock supply systems at the operational level. For this purpose, the Biomass Logistic Model (BLM) has been linked with the Geographic Informationmore » Systems based Biomass Intermodal Transportation model (BIT-UU) and extended with inter-continental transport routes. Case studies of herbaceous and woody biomass, produced in the U.S. Midwest and U.S. Southeast, respectively, and shipped to Europe for conversion to Fischer-Tropsch (FT) diesel are included to demonstrate how intermodal transportation and, in particular, overseas shipping integrates with the bioenergy supply chains. For the cases demonstrated, biomass can be supplied at 99 € Mg-1 to 117 € Mg-1 (dry) and converted to FT-diesel at 19 € GJ-1 to 24 € GJ-1 depending on the feedstock type and location, intermediate (chips or pellets) and size of the FT-diesel production plant. With the flexibility to change the design of supply chains as well as input variables, many alternative supply chain cases can be assessed.« less

  7. Early application of airway pressure release ventilation may reduce the duration of mechanical ventilation in acute respiratory distress syndrome.

    PubMed

    Zhou, Yongfang; Jin, Xiaodong; Lv, Yinxia; Wang, Peng; Yang, Yunqing; Liang, Guopeng; Wang, Bo; Kang, Yan

    2017-11-01

    Experimental animal models of acute respiratory distress syndrome (ARDS) have shown that the updated airway pressure release ventilation (APRV) methodologies may significantly improve oxygenation, maximize lung recruitment, and attenuate lung injury, without circulatory depression. This led us to hypothesize that early application of APRV in patients with ARDS would allow pulmonary function to recover faster and would reduce the duration of mechanical ventilation as compared with low tidal volume lung protective ventilation (LTV). A total of 138 patients with ARDS who received mechanical ventilation for <48 h between May 2015 to October 2016 while in the critical care medicine unit (ICU) of the West China Hospital of Sichuan University were enrolled in the study. Patients were randomly assigned to receive APRV (n = 71) or LTV (n = 67). The settings for APRV were: high airway pressure (P high ) set at the last plateau airway pressure (P plat ), not to exceed 30 cmH 2 O) and low airway pressure ( P low ) set at 5 cmH 2 O; the release phase (T low ) setting adjusted to terminate the peak expiratory flow rate to ≥ 50%; release frequency of 10-14 cycles/min. The settings for LTV were: target tidal volume of 6 mL/kg of predicted body weight; P plat not exceeding 30 cmH 2 O; positive end-expiratory pressure (PEEP) guided by the PEEP-FiO 2 table according to the ARDSnet protocol. The primary outcome was the number of days without mechanical ventilation from enrollment to day 28. The secondary endpoints included oxygenation, P plat , respiratory system compliance, and patient outcomes. Compared with the LTV group, patients in the APRV group had a higher median number of ventilator-free days {19 [interquartile range (IQR) 8-22] vs. 2 (IQR 0-15); P < 0.001}. This finding was independent of the coexisting differences in chronic disease. The APRV group had a shorter stay in the ICU (P = 0.003). The ICU mortality rate was 19.7% in the APRV group versus 34.3% in the

  8. 24 CFR 3280.704 - Fuel supply systems.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... be ventilated at top and bottom to facilitate diffusion of vapors. The compartment shall be... to permit diffusion of vapors and shall be insulated from the structural members of the body. Tanks...

  9. 24 CFR 3280.704 - Fuel supply systems.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... be ventilated at top and bottom to facilitate diffusion of vapors. The compartment shall be... to permit diffusion of vapors and shall be insulated from the structural members of the body. Tanks...

  10. 24 CFR 3280.704 - Fuel supply systems.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... be ventilated at top and bottom to facilitate diffusion of vapors. The compartment shall be... to permit diffusion of vapors and shall be insulated from the structural members of the body. Tanks...

  11. A dynamic ventilation model for gravity sewer networks.

    PubMed

    Wang, Y C; Nobi, N; Nguyen, T; Vorreiter, L

    2012-01-01

    To implement any effective odour and corrosion control technology in the sewer network, it is imperative that the airflow through gravity sewer airspaces be quantified. This paper presents a full dynamic airflow model for gravity sewer systems. The model, which is developed using the finite element method, is a compressible air transport model. The model has been applied to the North Head Sewerage Ocean Outfall System (NSOOS) and calibrated using the air pressure and airflow data collected during October 2008. Although the calibration is focused on forced ventilation, the model can be applied to natural ventilation as well.

  12. Laboratory Ventilation and Safety.

    ERIC Educational Resources Information Center

    Steere, Norman V.

    1965-01-01

    In order to meet the needs of both safety and economy, laboratory ventilation systems must effectively remove air-borne toxic and flammable materials and at the same time exhaust a minimum volume of air. Laboratory hoods are the most commonly used means of removing gases, dusts, mists, vapors, and fumed from laboratory operations. To be effective,…

  13. Effects of ventilation behaviour on indoor heat load based on test reference years.

    PubMed

    Rosenfelder, Madeleine; Koppe, Christina; Pfafferott, Jens; Matzarakis, Andreas

    2016-02-01

    Since 2003, most European countries established heat health warning systems to alert the population to heat load. Heat health warning systems are based on predicted meteorological conditions outdoors. But the majority of the European population spends a substantial amount of time indoors, and indoor thermal conditions can differ substantially from outdoor conditions. The German Meteorological Service (Deutscher Wetterdienst, DWD) extended the existing heat health warning system (HHWS) with a thermal building simulation model to consider heat load indoors. In this study, the thermal building simulation model is used to simulate a standardized building representing a modern nursing home, because elderly and sick people are most sensitive to heat stress. Different types of natural ventilation were simulated. Based on current and future test reference years, changes in the future heat load indoors were analyzed. Results show differences between the various ventilation options and the possibility to minimize the thermal heat stress during summer by using an appropriate ventilation method. Nighttime ventilation for indoor thermal comfort is most important. A fully opened window at nighttime and the 2-h ventilation in the morning and evening are more sufficient to avoid heat stress than a tilted window at nighttime and the 1-h ventilation in the morning and the evening. Especially the ventilation in the morning seems to be effective to keep the heat load indoors low. Comparing the results for the current and the future test reference years, an increase of heat stress on all ventilation types can be recognized.

  14. Effects of ventilation behaviour on indoor heat load based on test reference years

    NASA Astrophysics Data System (ADS)

    Rosenfelder, Madeleine; Koppe, Christina; Pfafferott, Jens; Matzarakis, Andreas

    2016-02-01

    Since 2003, most European countries established heat health warning systems to alert the population to heat load. Heat health warning systems are based on predicted meteorological conditions outdoors. But the majority of the European population spends a substantial amount of time indoors, and indoor thermal conditions can differ substantially from outdoor conditions. The German Meteorological Service (Deutscher Wetterdienst, DWD) extended the existing heat health warning system (HHWS) with a thermal building simulation model to consider heat load indoors. In this study, the thermal building simulation model is used to simulate a standardized building representing a modern nursing home, because elderly and sick people are most sensitive to heat stress. Different types of natural ventilation were simulated. Based on current and future test reference years, changes in the future heat load indoors were analyzed. Results show differences between the various ventilation options and the possibility to minimize the thermal heat stress during summer by using an appropriate ventilation method. Nighttime ventilation for indoor thermal comfort is most important. A fully opened window at nighttime and the 2-h ventilation in the morning and evening are more sufficient to avoid heat stress than a tilted window at nighttime and the 1-h ventilation in the morning and the evening. Especially the ventilation in the morning seems to be effective to keep the heat load indoors low. Comparing the results for the current and the future test reference years, an increase of heat stress on all ventilation types can be recognized.

  15. Short-term airing by natural ventilation - implication on IAQ and thermal comfort.

    PubMed

    Heiselberg, P; Perino, M

    2010-04-01

    The need to improve the energy efficiency of buildings requires new and more efficient ventilation systems. It has been demonstrated that innovative operating concepts that make use of natural ventilation seem to be more appreciated by occupants. Among the available ventilation strategies that are currently available, buoyancy driven, single-sided natural ventilation has proved to be very effective and can provide high air change rates for temperature and Indoor Air Quality (IAQ) control. However, to promote a wider distribution of these systems an improvement in the knowledge of their working principles is necessary. The present study analyses and presents the results of an experimental evaluation of airing performance in terms of ventilation characteristics, IAQ and thermal comfort. It includes investigations of the consequences of opening time, opening frequency, opening area and expected airflow rate, ventilation efficiency, thermal comfort and dynamic temperature conditions. A suitable laboratory test rig was developed to perform extensive experimental analyses of the phenomenon under controlled and repeatable conditions. The results showed that short-term window airing is very effective and can provide both acceptable IAQ and thermal comfort conditions in buildings. Practical Implications This study gives the necessary background and in-depth knowledge of the performance of window airing by single-sided natural ventilation necessary for the development of control strategies for window airing (length of opening period and opening frequency) for optimum IAQ and thermal comfort in naturally ventilated buildings.

  16. Low-Flow Extracorporeal Carbon Dioxide Removal Using the Hemolung Respiratory Dialysis System® to Facilitate Lung-Protective Mechanical Ventilation in Acute Respiratory Distress Syndrome.

    PubMed

    Akkanti, Bindu; Rajagopal, Keshava; Patel, Kirti P; Aravind, Sangeeta; Nunez-Centanu, Emmanuel; Hussain, Rahat; Shabari, Farshad Raissi; Hofstetter, Wayne L; Vaporciyan, Ara A; Banjac, Igor S; Kar, Biswajit; Gregoric, Igor D; Loyalka, Pranav

    2017-06-01

    Extracorporeal carbon dioxide removal (ECCO 2 R) permits reductions in alveolar ventilation requirements that the lungs would otherwise have to provide. This concept was applied to a case of hypercapnia refractory to high-level invasive mechanical ventilator support. We present a case of an 18-year-old man who developed post-pneumonectomy acute respiratory distress syndrome (ARDS) after resection of a mediastinal germ cell tumor involving the left lung hilum. Hypercapnia and hypoxemia persisted despite ventilator support even at traumatic levels. ECCO 2 R using a miniaturized system was instituted and provided effective carbon dioxide elimination. This facilitated establishment of lung-protective ventilator settings and lung function recovery. Extracorporeal lung support increasingly is being applied to treat ARDS. However, conventional extracorporeal membrane oxygenation (ECMO) generally involves using large cannulae capable of carrying high flow rates. A subset of patients with ARDS has mixed hypercapnia and hypoxemia despite high-level ventilator support. In the absence of profound hypoxemia, ECCO 2 R may be used to reduce ventilator support requirements to lung-protective levels, while avoiding risks associated with conventional ECMO.

  17. RHIC BEAM ABORT KICKER POWER SUPPLY SYSTEM COMMISSIONING EXPERIENCE AND REMAINING ISSUES.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    ZHANG,W.; AHRENS,L.A.; MI,J.

    2001-06-18

    The RHIC Beam Abort Kicker Power Supply Systems commissioning experience and the remaining issues will be reported in this paper. The RHIC Blue Ring Beam Abort Kicker Power Supply System initial commissioning took place in June 1999. Its identical system in Yellow Ring was brought on line during Spring 2000. Each of the RHIC Beam Abort Kicker Power Supply Systems consists of five high voltage modulators and subsystems. These systems are critical devices for RHIC machine protection and environmental protection. They are required to be effective, reliable and operating with sufficient redundancy to safely abort the beam to its beammore » dump at the end of accumulation or at any time when they are commanded. To deflect 66 GeV ion beam to the beam absorbers, the RHIC Beam Abort Kicker Power Supply Systems were operated at 22 kV level. The RHIC 2000 commissioning run was very successful.« less

  18. Reducing the ingress of urban noise through natural ventilation openings.

    PubMed

    Oldham, D J; de Salis, M H; Sharples, S

    2004-01-01

    For buildings in busy urban areas affected by high levels of road traffic noise the potential to use natural ventilation can be limited by excessive noise entering through ventilation openings. This paper is concerned with techniques to reduce noise ingress into naturally ventilated buildings while minimizing airflow path resistance. A combined experimental and theoretical approach to the interaction of airflow and sound transmission through ventilators for natural ventilation applications is described. A key element of the investigation has been the development of testing facilities capable of measuring the airflow and sound transmission losses for a range of ventilation noise control strategies. It is demonstrated that a combination of sound reduction mechanisms -- one covering low frequency sound and another covering high frequency sound -- is required to attenuate effectively noise from typical urban sources. A method is proposed for quantifying the acoustic performance of different strategies to enable comparisons and informed decisions to be made leading to the possibility of a design methodology for optimizing the ventilation and acoustic performance of different strategies. The need for employing techniques for combating low frequency sound in tandem with techniques for reducing high frequency sound in reducing the ingress of noise from urban sources such as road traffic to acceptable levels is demonstrated. A technique is proposed for enabling the acoustic and airflow performance of apertures for natural ventilation systems to be designed simultaneously.

  19. 14 CFR 125.117 - Ventilation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Ventilation. 125.117 Section 125.117 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS....117 Ventilation. Each passenger or crew compartment must be suitably ventilated. Carbon monoxide...

  20. Multicenter comparative study of conventional mechanical gas ventilation to tidal liquid ventilation in oleic acid injured sheep.

    PubMed

    Wolfson, Marla R; Hirschl, Ronald B; Jackson, J Craig; Gauvin, France; Foley, David S; Lamm, Wayne J E; Gaughan, John; Shaffer, Thomas H

    2008-01-01

    We performed a multicenter study to test the hypothesis that tidal liquid ventilation (TLV) would improve cardiopulmonary, lung histomorphological, and inflammatory profiles compared with conventional mechanical gas ventilation (CMV). Sheep were studied using the same volume-controlled, pressure-limited ventilator systems, protocols, and treatment strategies in three independent laboratories. Following baseline measurements, oleic acid lung injury was induced and animals were randomized to 4 hours of CMV or TLV targeted to "best PaO2" and PaCO2 35 to 60 mm Hg. The following were significantly higher (p < 0.01) during TLV than CMV: PaO2, venous oxygen saturation, respiratory compliance, cardiac output, stroke volume, oxygen delivery, ventilatory efficiency index; alveolar area, lung % gas exchange space, and expansion index. The following were lower (p < 0.01) during TLV compared with CMV: inspiratory and expiratory pause pressures, mean airway pressure, minute ventilation, physiologic shunt, plasma lactate, lung interleukin-6, interleukin-8, myeloperoxidase, and composite total injury score. No significant laboratories by treatment group interactions were found. In summary, TLV resulted in improved cardiopulmonary physiology at lower ventilatory requirements with more favorable histological and inflammatory profiles than CMV. As such, TLV offers a feasible ventilatory alternative as a lung protective strategy in this model of acute lung injury.

  1. Pretest Predictions for Ventilation Tests

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Y. Sun; H. Yang; H.N. Kalia

    The objective of this calculation is to predict the temperatures of the ventilating air, waste package surface, concrete pipe walls, and insulation that will be developed during the ventilation tests involving various test conditions. The results will be used as input to the following three areas: (1) Decisions regarding testing set-up and performance. (2) Assessing how best to scale the test phenomena measured. (3) Validating numerical approach for modeling continuous ventilation. The scope of the calculation is to identify the physical mechanisms and parameters related to thermal response in the ventilation tests, and develop and describe numerical methods that canmore » be used to calculate the effects of continuous ventilation. Sensitivity studies to assess the impact of variation of linear power densities (linear heat loads) and ventilation air flow rates are included. The calculation is limited to thermal effect only.« less

  2. 30 CFR 75.333 - Ventilation controls.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Ventilation controls. 75.333 Section 75.333... MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Ventilation § 75.333 Ventilation controls. (a) For... ventilation control devices constructed after November 15, 1992, shall be built and maintained— (1) Between...

  3. 30 CFR 75.333 - Ventilation controls.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Ventilation controls. 75.333 Section 75.333... MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Ventilation § 75.333 Ventilation controls. (a) For... ventilation control devices constructed after November 15, 1992, shall be built and maintained— (1) Between...

  4. Increasing the inspiratory time and I:E ratio during mechanical ventilation aggravates ventilator-induced lung injury in mice.

    PubMed

    Müller-Redetzky, Holger C; Felten, Matthias; Hellwig, Katharina; Wienhold, Sandra-Maria; Naujoks, Jan; Opitz, Bastian; Kershaw, Olivia; Gruber, Achim D; Suttorp, Norbert; Witzenrath, Martin

    2015-01-28

    Lung-protective ventilation reduced acute respiratory distress syndrome (ARDS) mortality. To minimize ventilator-induced lung injury (VILI), tidal volume is limited, high plateau pressures are avoided, and positive end-expiratory pressure (PEEP) is applied. However, the impact of specific ventilatory patterns on VILI is not well defined. Increasing inspiratory time and thereby the inspiratory/expiratory ratio (I:E ratio) may improve oxygenation, but may also be harmful as the absolute stress and strain over time increase. We thus hypothesized that increasing inspiratory time and I:E ratio aggravates VILI. VILI was induced in mice by high tidal-volume ventilation (HVT 34 ml/kg). Low tidal-volume ventilation (LVT 9 ml/kg) was used in control groups. PEEP was set to 2 cm H2O, FiO2 was 0.5 in all groups. HVT and LVT mice were ventilated with either I:E of 1:2 (LVT 1:2, HVT 1:2) or 1:1 (LVT 1:1, HVT 1:1) for 4 hours or until an alternative end point, defined as mean arterial blood pressure below 40 mm Hg. Dynamic hyperinflation due to the increased I:E ratio was excluded in a separate group of animals. Survival, lung compliance, oxygenation, pulmonary permeability, markers of pulmonary and systemic inflammation (leukocyte differentiation in lung and blood, analyses of pulmonary interleukin-6, interleukin-1β, keratinocyte-derived chemokine, monocyte chemoattractant protein-1), and histopathologic pulmonary changes were analyzed. LVT 1:2 or LVT 1:1 did not result in VILI, and all individuals survived the ventilation period. HVT 1:2 decreased lung compliance, increased pulmonary neutrophils and cytokine expression, and evoked marked histologic signs of lung injury. All animals survived. HVT 1:1 caused further significant worsening of oxygenation, compliance and increased pulmonary proinflammatory cytokine expression, and pulmonary and blood neutrophils. In the HVT 1:1 group, significant mortality during mechanical ventilation was observed. According to the "baby lung

  5. Climate Considerations Of The Electricity Supply Systems In Industries

    NASA Astrophysics Data System (ADS)

    Asset, Khabdullin; Zauresh, Khabdullina

    2014-12-01

    The study is focused on analysis of climate considerations of electricity supply systems in a pellet industry. The developed analysis model consists of two modules: statistical data of active power losses evaluation module and climate aspects evaluation module. The statistical data module is presented as a universal mathematical model of electrical systems and components of industrial load. It forms a basis for detailed accounting of power loss from the voltage levels. On the basis of the universal model, a set of programs is designed to perform the calculation and experimental research. It helps to obtain the statistical characteristics of the power losses and loads of the electricity supply systems and to define the nature of changes in these characteristics. Within the module, several methods and algorithms for calculating parameters of equivalent circuits of low- and high-voltage ADC and SD with a massive smooth rotor with laminated poles are developed. The climate aspects module includes an analysis of the experimental data of power supply system in pellet production. It allows identification of GHG emission reduction parameters: operation hours, type of electrical motors, values of load factor and deviation of standard value of voltage.

  6. Cost containment and mechanical ventilation in the United States.

    PubMed

    Cohen, I L; Booth, F V

    1994-08-01

    In many ICUs, admission and discharge hinge on the need for intubation and ventilatory support. As few as 5% to 10% of ICU patients require prolonged mechanical ventilation, and this patient group consumes > or = 50% of ICU patient days and ICU resources. Prolonged ventilatory support and chronic ventilator dependency, both in the ICU and non-ICU settings, have a significant and growing impact on healthcare economics. In the United States, the need for prolonged mechanical ventilation is increasingly recognized as separate and distinct from the initial diagnosis and/or procedure that leads to hospitalization. This distinction has led to improved reimbursement under the prospective diagnosis-related group (DRG) system, and demands more precise accounting from healthcare providers responsible for these patients. Using both published and theoretical examples, mechanical ventilation in the United States is discussed, with a focus on cost containment. Included in the discussion are ventilator teams, standards of care, management protocols, stepdown units, rehabilitation units, and home care. The expanding role of total quality management (TQM) is also presented.

  7. Susceptibility to ventilator induced lung injury is increased in senescent rats

    PubMed Central

    2013-01-01

    Introduction The principal mechanisms of ventilator induced lung injury (VILI) have been investigated in numerous animal studies. However, prospective data on the effect of old age on VILI are limited. Under the hypothesis that susceptibility to VILI is increased in old age, we investigated the pulmonary and extrapulmonary effects of mechanical ventilation with high tidal volume (VT) in old compared to young adult animals. Interventions Old (19.1 ± 3.0 months) and young adult (4.4 ± 1.3 months) male Wistar rats were anesthetized and mechanically ventilated (positive end-expiratory pressure 5 cmH2O, fraction of inspired oxygen 0.4, respiratory rate 40/minute) with a tidal volume (VT) of either 8, 16 or 24 ml/kg for four hours. Respiratory and hemodynamic variables, including cardiac output, and markers of systemic inflammation were recorded throughout the ventilation period. Lung histology and wet-to-dry weight ratio, injury markers in lung lavage and respiratory system pressure-volume curves were assessed post mortem. Basic pulmonary characteristics were assessed in non-ventilated animals. Results Compared to young adult animals, high VT (24 ml/kg body weight) caused more lung injury in old animals as indicated by decreased oxygenation (arterial oxygen tension (PaO2): 208 ± 3 vs. 131 ± 20 mmHg; P <0.05), increased lung wet-to-dry-weight ratio (5.61 ± 0.29 vs. 7.52 ± 0.27; P <0.05), lung lavage protein (206 ± 52 mg/l vs. 1,432 ± 101; P <0.05) and cytokine (IL-6: 856 ± 448 vs. 3,283 ± 943 pg/ml; P <0.05) concentration. In addition, old animals ventilated with high VT had more systemic inflammation than young animals (IL-1β: 149 ± 44 vs. 272 ± 36 pg/ml; P <0.05 - young vs. old, respectively). Conclusions Ventilation with unphysiologically large tidal volumes is associated with more lung injury in old compared to young rats. Aggravated pulmonary and systemic inflammation is a key finding in old animals developing VILI. PMID:23710684

  8. Ventilation practices in subarachnoid hemorrhage: a cohort study exploring the use of lung protective ventilation.

    PubMed

    Marhong, Jonathan D; Ferguson, Niall D; Singh, Jeffrey M

    2014-10-01

    Acute respiratory distress syndrome (ARDS) is common following aneurysmal subarachnoid hemorrhage (SAH), but the influence of mechanical ventilator settings on its development is unclear. We sought to determine adherence to lung protective thresholds in ventilated patients with SAH and describe the association between ventilator settings and subsequent development of ARDS. We conducted a retrospective cohort study of consecutive patients receiving mechanical ventilation within 72 h of SAH at a single academic center. Ventilator settings and blood gas data were collected twice daily for the first 7 days of ventilation along with ICU and hospital outcomes. Lung protective ventilation was defined as follows: tidal volume ≤8 mL/kg of predicted body weight, positive end-expiratory pressure (PEEP) ≥5 cm H(2)O, and peak or plateau pressure ≤30 cm H(2)O. The development of ARDS was ascertained retrospectively by PaO(2)/FiO(2) ≤300 with new bilateral lung opacities on chest X-ray within one day of hypoxemia. We identified 62 patients who underwent early mechanical ventilation following SAH. PS and Continuous Positive Airway Pressure were common ventilator modes with a median tidal volume of 7.8 mL/kg [interquartile range 6.8-8.8], median peak pressure of 14 cm H(2)O [IQR 12-17], and median PEEP of 5 cm H(2)O [IQR 5-6]. Adherence to tidal volumes ≤8 mL/kg was seen in 64 % of all observations and peak pressures <30 cm H(2)O were 94 % of all observations. All three lung protective criteria were seen in 58 % of all observations. Thirty-one patients (50 %) were determined to have ARDS. ARDS patients were more frequently ventilated with a peak pressure >30 cm H(2)O (11.3 % of ARDS ventilation days vs. 0 % of non-ARDS ventilation days; p < 0.01). Initial tidal volume was not associated with subsequent development of ARDS in univariate (p = 0.6) or multivariate analysis (p = 0.49). Only the number of ARDS risk factors was independently associated with the development of

  9. Equation Discovery for Model Identification in Respiratory Mechanics of the Mechanically Ventilated Human Lung

    NASA Astrophysics Data System (ADS)

    Ganzert, Steven; Guttmann, Josef; Steinmann, Daniel; Kramer, Stefan

    Lung protective ventilation strategies reduce the risk of ventilator associated lung injury. To develop such strategies, knowledge about mechanical properties of the mechanically ventilated human lung is essential. This study was designed to develop an equation discovery system to identify mathematical models of the respiratory system in time-series data obtained from mechanically ventilated patients. Two techniques were combined: (i) the usage of declarative bias to reduce search space complexity and inherently providing the processing of background knowledge. (ii) A newly developed heuristic for traversing the hypothesis space with a greedy, randomized strategy analogical to the GSAT algorithm. In 96.8% of all runs the applied equation discovery system was capable to detect the well-established equation of motion model of the respiratory system in the provided data. We see the potential of this semi-automatic approach to detect more complex mathematical descriptions of the respiratory system from respiratory data.

  10. Dynamics of tropical oxygen minium zones (OMZ): The role of vertical mixing and eddy stirring in ventilating the OMZ in the tropical Atlantic

    NASA Astrophysics Data System (ADS)

    Visbeck, M.; Banyte, D.; Brandt, P.; Dengler, M.; Fischer, T.; Karstensen, J.; Krahmann, G.; Tanhua, T. S.; Stramma, L.

    2013-12-01

    Equatorial Dynamics provide an essential influence on the ventilation pathways of well oxygenated surface water on their route to tropical oxygen minimum zones (OMZ). The large scale wind driven circulation shield OMZs from the direct ventilation pathways. They are located in the so called ';shadow zones' equator ward of the subtropical gyres. From what is known most of the oxygen is supplied via pathways from the western boundary modulated by the complex zonal equatorial current system and marginally by vertical mixing. What was less clear is which of the possible pathways are most effective in transporting dissolved oxygen towards the OMZ. A collaborative research program focused on the dynamics of oxygen minimum zones, called SFB754 "Climate - Biogeochemistry Interactions in the Tropical Ocean", allowed us to conduct two ocean tracer release experiments to investigate the vertical and horizontal mixing rates and associated oxygen transports. Specifically we report on the first deliberate tracer release experiment (GUTRE, Guinea Upwelling Tracer Release Experiment) in the tropical northeast Atlantic carried out in order to determine the diapycnal diffusivity coefficient in the upper layer of the OMZ. A tracer (CF3SF5) was injected in spring of 2008 and subsequently measured during three designated tracer survey cruises until the end of 2010. We found that, generally, the diffusivity is larger than expected for low latitudes and similar in magnitude to what has previously been experimentally determined in the Canary Basin. When combining the tracer study with estimates of diapycnal mixing based on microstructure profiling and a newly developed method using ship board ADCPs we were able to compute the vertical oxygen flux and its divergence for the OMZ. To our surprise, the vertical flux of oxygen by diapycnal mixing provides about 30% of the total ventilation. The estimate was derived from the simple advection-diffusion model taking into account moored and ship

  11. Winter ventilation rates at primary schools: comparison between Portugal and Finland.

    PubMed

    Canha, N; Almeida, S M; Freitas, M C; Täubel, M; Hänninen, O

    2013-01-01

    This study focused on examination of ventilation rates in classrooms with two different types of ventilation systems: natural and mechanical. Carbon dioxide (CO2) measurements were conducted in primary schools of Portugal characterized by natural ventilation and compared to Finland where mechanical ventilation is the norm. The winter period was selected since this season exerts a great influence in naturally ventilated classrooms, where opening of windows and doors occurs due to outdoor atmospheric conditions. The ventilation rates were calculated by monitoring CO2 concentrations generated by the occupants (used as a tracer gas) and application of the buildup phase method. A comparison between both countries' results was conducted with respect to ventilation rates and how these levels corresponded to national regulatory standards. Finnish primary schools (n = 2) registered a mean ventilation rate of 13.3 L/s per person, which is higher than the recommended ventilation standards. However, the Finnish classroom that presented the lowest ventilation rate (7.2 L/s per person) displayed short-term CO2 levels above 1200 ppm, which is the threshold limit value (TLV) recommended by national guidelines. The Portuguese classrooms (n = 2) showed low ventilation rates with mean values of 2.4 L/s per person, which is markedly lower than the minimum recommended value of 7 L/s per person as defined by ASHRAE and 20% less than the REHVA minimum of 3 L/s per person. Carbon dioxide levels of 1000 ppm, close to the TLV of 1200 ppm, were also reached in both Portuguese classrooms studied. The situation in Portugal indicates a potentially serious indoor air quality problem and strengthens the need for intervention to improve ventilation rates in naturally ventilated classrooms.

  12. Replicating human expertise of mechanical ventilation waveform analysis in detecting patient-ventilator cycling asynchrony using machine learning.

    PubMed

    Gholami, Behnood; Phan, Timothy S; Haddad, Wassim M; Cason, Andrew; Mullis, Jerry; Price, Levi; Bailey, James M

    2018-06-01

    - Acute respiratory failure is one of the most common problems encountered in intensive care units (ICU) and mechanical ventilation is the mainstay of supportive therapy for such patients. A mismatch between ventilator delivery and patient demand is referred to as patient-ventilator asynchrony (PVA). An important hurdle in addressing PVA is the lack of a reliable framework for continuously and automatically monitoring the patient and detecting various types of PVA. - The problem of replicating human expertise of waveform analysis for detecting cycling asynchrony (i.e., delayed termination, premature termination, or none) was investigated in a pilot study involving 11 patients in the ICU under invasive mechanical ventilation. A machine learning framework is used to detect cycling asynchrony based on waveform analysis. - A panel of five experts with experience in PVA evaluated a total of 1377 breath cycles from 11 mechanically ventilated critical care patients. The majority vote was used to label each breath cycle according to cycling asynchrony type. The proposed framework accurately detected the presence or absence of cycling asynchrony with sensitivity (specificity) of 89% (99%), 94% (98%), and 97% (93%) for delayed termination, premature termination, and no cycling asynchrony, respectively. The system showed strong agreement with human experts as reflected by the kappa coefficients of 0.90, 0.91, and 0.90 for delayed termination, premature termination, and no cycling asynchrony, respectively. - The pilot study establishes the feasibility of using a machine learning framework to provide waveform analysis equivalent to an expert human. Copyright © 2018 Elsevier Ltd. All rights reserved.

  13. Master's Degree in Management Information Systems with a Supply Chain Management Focus

    ERIC Educational Resources Information Center

    Ramaswamy, Kizhanatham V.; Boyd, Joseph L.; Desai, Mayur

    2007-01-01

    A graduate curriculum in Management Information Systems with a Supply Chain Management focus is presented. The motivation for this endeavor stems from the fact that the global scope of modern business organizations and the competitive environment in which they operate, requires an information system leveraged supply chain management system (SCM)…

  14. Oxygen consumption of a pneumatically controlled ventilator in a field anesthesia machine.

    PubMed

    Szpisjak, Dale F; Javernick, Elizabeth N; Kyle, Richard R; Austin, Paul N

    2008-12-01

    Field anesthesia machines (FAM) have been developed for remote locations where reliable supplies of compressed medical gases or electricity may be absent. In place of electricity, pneumatically controlled ventilators use compressed gas to power timing circuitry and actuate valves. We sought to determine the total O(2) consumption and ventilator gas consumption (drive gas [DG] plus pneumatic control [PC] gas) of a FAM's pneumatically controlled ventilator in mechanical models of high (HC) and low (LC) total thoracic compliance. The amount of total O(2) consumed by the Magellan-2200 (Oceanic Medical Products, Atchison, KS) FAM with pneumatically controlled ventilator was calculated using the ideal gas law and the measured mass of O(2) consumed from E cylinders. DG to the bellows canister assembly was measured with the Wright Respirometer Mk 8 (Ferraris Respiratory Europe, Hertford, UK). PC gas consumption was calculated by subtracting DG and fresh gas flow (FGF) from the total O(2) consumed from the E cylinder. The delivered tidal volume (V(T)) was measured with a pneumotach (Hans Rudolph, KS City, MO). Three different V(T) were tested (500, 750, and 1000 mL) with two lung models (HC and LC) using the Vent Aid Training Test Lung (MI Instruments, Grand Rapids, MI). Respiratory variables included an I:E of 1:2, FGF of 1 L/min, and respiratory rate of 10 breaths/min. Total O(2) consumption was directly proportional to V(T) and inversely proportional to compliance. The smallest total O(2) consumption rate (including FGF) was 9.3 +/- 0.4 L/min in the HC-500 model and the largest was 15.9 +/- 0.5 L/min in the LC-1000 model (P < 0.001). The mean PC circuitry consumption was 3.9 +/- 0.24 L/min or 390 mL +/- 24 mL/breath. To prepare for loss of central DG supply, patient safety will be improved by estimating cylinder duration for low total thoracic compliance. Using data from the smaller compliance and greatest V(T) model (LC-1000), a full O(2) E cylinder would be depleted in

  15. Electric Transport Traction Power Supply System With Distributed Energy Sources

    NASA Astrophysics Data System (ADS)

    Abramov, E. Y.; Schurov, N. I.; Rozhkova, M. V.

    2016-04-01

    The paper states the problem of traction substation (TSS) leveling of daily-load curve for urban electric transport. The circuit of traction power supply system (TPSS) with distributed autonomous energy source (AES) based on photovoltaic (PV) and energy storage (ES) units is submitted here. The distribution algorithm of power flow for the daily traction load curve leveling is also introduced in this paper. In addition, it illustrates the implemented experiment model of power supply system.

  16. 21 CFR 868.5975 - Ventilator tubing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ventilator tubing. 868.5975 Section 868.5975 Food... DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5975 Ventilator tubing. (a) Identification. Ventilator tubing is a device intended for use as a conduit for gases between a ventilator and a patient...

  17. Wii, Kinect, and Move. Heart Rate, Oxygen Consumption, Energy Expenditure, and Ventilation due to Different Physically Active Video Game Systems in College Students.

    PubMed

    Scheer, Krista S; Siebrant, Sarah M; Brown, Gregory A; Shaw, Brandon S; Shaw, Ina

    Nintendo Wii, Sony Playstation Move , and Microsoft XBOX Kinect are home video gaming systems that involve player movement to control on-screen game play. Numerous investigations have demonstrated that playing Wii is moderate physical activity at best, but Move and Kinect have not been as thoroughly investigated. The purpose of this study was to compare heart rate, oxygen consumption, and ventilation while playing the games Wii Boxing, Kinect Boxing, and Move Gladiatorial Combat. Heart rate, oxygen consumption, and ventilation were measured at rest and during a graded exercise test in 10 males and 9 females (19.8 ± 0.33 y, 175.4 ± 2.0 cm, 80.2 ± 7.7 kg,). On another day, in a randomized order, the participants played Wii Boxing, K inect Boxing, and Move Gladiatorial Combat while heart rate, ventilation, and oxygen consumption were measured. There were no differences in heart rate (116.0 ± 18.3 vs. 119.3 ± 17.6 vs. 120.1 ± 17.6 beats/min), oxygen consumption (9.2 ± 3.0 vs. 10.6 ± 2.4 vs. 9.6 ± 2.4 ml/kg/min), or minute ventilation (18.9 ± 5.7 vs. 20.8 ± 8.0 vs. 19.7 ± 6.4 L/min) when playing Wii boxing, Kinect boxing, or Move Gladiatorial Combat (respectively). Playing Nintendo Wii Boxing, XBOX Kinect Boxing, and Sony PlayStation Move Gladiatorial Combat all increase heart rate, oxygen consumption, and ventilation above resting levels but there were no significant differences between gaming systems. Overall, playing a "physically active" home video game system does not meet the minimal threshold for moderate intensity physical activity, regardless of gaming system.

  18. Wii, Kinect, and Move. Heart Rate, Oxygen Consumption, Energy Expenditure, and Ventilation due to Different Physically Active Video Game Systems in College Students

    PubMed Central

    SCHEER, KRISTA S.; SIEBRANT, SARAH M.; BROWN, GREGORY A.; SHAW, BRANDON S.; SHAW, INA

    2014-01-01

    Nintendo Wii, Sony Playstation Move, and Microsoft XBOX Kinect are home video gaming systems that involve player movement to control on-screen game play. Numerous investigations have demonstrated that playing Wii is moderate physical activity at best, but Move and Kinect have not been as thoroughly investigated. The purpose of this study was to compare heart rate, oxygen consumption, and ventilation while playing the games Wii Boxing, Kinect Boxing, and Move Gladiatorial Combat. Heart rate, oxygen consumption, and ventilation were measured at rest and during a graded exercise test in 10 males and 9 females (19.8 ± 0.33 y, 175.4 ± 2.0 cm, 80.2 ± 7.7 kg,). On another day, in a randomized order, the participants played Wii Boxing, Kinect Boxing, and Move Gladiatorial Combat while heart rate, ventilation, and oxygen consumption were measured. There were no differences in heart rate (116.0 ± 18.3 vs. 119.3 ± 17.6 vs. 120.1 ± 17.6 beats/min), oxygen consumption (9.2 ± 3.0 vs. 10.6 ± 2.4 vs. 9.6 ± 2.4 ml/kg/min), or minute ventilation (18.9 ± 5.7 vs. 20.8 ± 8.0 vs. 19.7 ± 6.4 L/min) when playing Wii boxing, Kinect boxing, or Move Gladiatorial Combat (respectively). Playing Nintendo Wii Boxing, XBOX Kinect Boxing, and Sony PlayStation Move Gladiatorial Combat all increase heart rate, oxygen consumption, and ventilation above resting levels but there were no significant differences between gaming systems. Overall, playing a “physically active” home video game system does not meet the minimal threshold for moderate intensity physical activity, regardless of gaming system. PMID:27182399

  19. Use of multilevel modeling for determining optimal parameters of heat supply systems

    NASA Astrophysics Data System (ADS)

    Stennikov, V. A.; Barakhtenko, E. A.; Sokolov, D. V.

    2017-07-01

    The problem of finding optimal parameters of a heat-supply system (HSS) is in ensuring the required throughput capacity of a heat network by determining pipeline diameters and characteristics and location of pumping stations. Effective methods for solving this problem, i.e., the method of stepwise optimization based on the concept of dynamic programming and the method of multicircuit optimization, were proposed in the context of the hydraulic circuit theory developed at Melentiev Energy Systems Institute (Siberian Branch, Russian Academy of Sciences). These methods enable us to determine optimal parameters of various types of piping systems due to flexible adaptability of the calculation procedure to intricate nonlinear mathematical models describing features of used equipment items and methods of their construction and operation. The new and most significant results achieved in developing methodological support and software for finding optimal parameters of complex heat supply systems are presented: a new procedure for solving the problem based on multilevel decomposition of a heat network model that makes it possible to proceed from the initial problem to a set of interrelated, less cumbersome subproblems with reduced dimensionality; a new algorithm implementing the method of multicircuit optimization and focused on the calculation of a hierarchical model of a heat supply system; the SOSNA software system for determining optimum parameters of intricate heat-supply systems and implementing the developed methodological foundation. The proposed procedure and algorithm enable us to solve engineering problems of finding the optimal parameters of multicircuit heat supply systems having large (real) dimensionality, and are applied in solving urgent problems related to the optimal development and reconstruction of these systems. The developed methodological foundation and software can be used for designing heat supply systems in the Central and the Admiralty regions in

  20. Inhaled Antibiotics for Ventilator-Associated Infections.

    PubMed

    Palmer, Lucy B

    2017-09-01

    Multidrug-resistant organisms are creating a challenge for physicians treating the critically ill. As new antibiotics lag behind the emergence of worsening resistance, intensivists in countries with high rates of extensively drug-resistant bacteria are turning to inhaled antibiotics as adjunctive therapy. These drugs can provide high concentrations of drug in the lung that could not be achieved with intravenous antibiotics without significant systemic toxicity. This article summarizes current evidence describing the use of inhaled antibiotics for the treatment of bacterial ventilator-associated pneumonia and ventilator-associated tracheobronchitis. Preliminary data suggest aerosolized antimicrobials may effectively treat resistant pathogens with high minimum inhibitory concentrations. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Power supply system for negative ion source at IPR

    NASA Astrophysics Data System (ADS)

    Gahlaut, Agrajit; Sonara, Jashwant; Parmar, K. G.; Soni, Jignesh; Bandyopadhyay, M.; Singh, Mahendrajit; Bansal, Gourab; Pandya, Kaushal; Chakraborty, Arun

    2010-02-01

    The first step in the Indian program on negative ion beams is the setting up of Negative ion Experimental Assembly - RF based, where 100 kW of RF power shall be coupled to a plasma source producing plasma of density ~5 × 1012 cm-3, from which ~ 10 A of negative ion beam shall be produced and accelerated to 35 kV, through an electrostatic ion accelerator. The experimental system is modelled similar to the RF based negative ion source, BATMAN presently operating at IPP, Garching, Germany. The mechanical system for Negative Ion Source Assembly is close to the IPP source, remaining systems are designed and procured principally from indigenous sources, keeping the IPP configuration as a base line. High voltage (HV) and low voltage (LV) power supplies are two key constituents of the experimental setup. The HV power supplies for extraction and acceleration are rated for high voltage (~15 to 35kV), and high current (~ 15 to 35A). Other attributes are, fast rate of voltage rise (< 5ms), good regulation (< ±1%), low ripple (< ±2%), isolation (~50kV), low energy content (< 10J) and fast cut-off (< 100μs). The low voltage (LV) supplies required for biasing and providing heating power to the Cesium oven and the plasma grids; have attributes of low ripple, high stability, fast and precise regulation, programmability and remote operation. These power supplies are also equipped with over-voltage, over-current and current limit (CC Mode) protections. Fault diagnostics, to distinguish abnormal rise in currents (breakdown faults) with over-currents is enabled using fast response breakdown and over-current protection scheme. To restrict the fault energy deposited on the ion source, specially designed snubbers are implemented in each (extraction and acceleration) high voltage path to swap the surge energy. Moreover, the monitoring status and control signals from these power supplies are required to be electrically (~ 50kV) isolated from the system. The paper shall present the

  2. Quantifying air distribution, ventilation effectiveness and airborne pollutant transport in an aircraft cabin mockup

    NASA Astrophysics Data System (ADS)

    Wang, Aijun

    The health, safety and comfort of passengers during flight inspired this research into cabin air quality, which is closely related to its airflow distribution, ventilation effectiveness and airborne pollutant transport. The experimental facility is a full-scale aircraft cabin mockup. A volumetric particle tracking velocimetry (VPTV) technique was enhanced by incorporating a self-developed streak recognition algorithm. Two stable recirculation regions, the reverse flows above the seats and the main air jets from the air supply inlets formed the complicated airflow patterns inside the cabin mockup. The primary air flow was parallel to the passenger rows. The small velocity component in the direction of the cabin depth caused less net air exchange between the passenger rows than that parallel to the passenger rows. Different total air supply rate changed the developing behaviors of the main air jets, leading to different local air distribution patterns. Two indices, Local mean age of air and ventilation effectiveness factor (VEF), were measured at five levels of air supply rate and two levels of heating load. Local mean age of air decreased linearly with an increase in the air supply rate, while the VEF remained consistent when the air supply rate varied. The thermal buoyancy force from the thermal plume generated the upside plume flow, opposite to the main jet flow above the boundary seats and thus lowered the local net air exchange. The airborne transport dynamics depends on the distance between the source and the receptors, the relative location of pollutant source, and air supply rate. Exposure risk was significantly reduced with increased distance between source and receptors. Another possible way to decrease the exposure risk was to position the release source close to the exhaust outlets. Increasing the air supply rate could be an effective solution under some emergency situations. The large volume of data regarding the three-dimensional air velocities was

  3. NanoClusters Enhance Drug Delivery in Mechanical Ventilation

    NASA Astrophysics Data System (ADS)

    Pornputtapitak, Warangkana

    The overall goal of this thesis was to develop a dry powder delivery system for patients on mechanical ventilation. The studies were divided into two parts: the formulation development and the device design. The pulmonary system is an attractive route for drug delivery since the lungs have a large accessible surface area for treatment or drug absorption. For ventilated patients, inhaled drugs have to successfully navigate ventilator tubing and an endotracheal tube. Agglomerates of drug nanoparticles (also known as 'NanoClusters') are fine dry powder aerosols that were hypothesized to enable drug delivery through ventilator circuits. This Thesis systematically investigated formulations of NanoClusters and their aerosol performance in a conventional inhaler and a device designed for use during mechanical ventilation. These engineered powders of budesonide (NC-Bud) were delivered via a MonodoseRTM inhaler or a novel device through commercial endotracheal tubes, and analyzed by cascade impaction. NC-Bud had a higher efficiency of aerosol delivery compared to micronized stock budesonide. The delivery efficiency was independent of ventilator parameters such as inspiration patterns, inspiration volumes, and inspiration flow rates. A novel device designed to fit directly to the ventilator and endotracheal tubing connections and the MonodoseRTM inhaler showed the same efficiency of drug delivery. The new device combined with NanoCluster formulation technology, therefore, allowed convenient and efficient drug delivery through endotracheal tubes. Furthermore, itraconazole (ITZ), a triazole antifungal agent, was formulated as a NanoCluster powder via milling (top-down process) or precipitation (bottom-up process) without using any excipients. ITZ NanoClusters prepared by wet milling showed better aerosol performance compared to micronized stock ITZ and ITZ NanoClusters prepared by precipitation. ITZ NanoClusters prepared by precipitation methods also showed an amorphous state

  4. Variable Ventilation Improved Respiratory System Mechanics and Ameliorated Pulmonary Damage in a Rat Model of Lung Ischemia-Reperfusion.

    PubMed

    Soluri-Martins, André; Moraes, Lillian; Santos, Raquel S; Santos, Cintia L; Huhle, Robert; Capelozzi, Vera L; Pelosi, Paolo; Silva, Pedro L; de Abreu, Marcelo Gama; Rocco, Patricia R M

    2017-01-01

    Lung ischemia-reperfusion injury remains a major complication after lung transplantation. Variable ventilation (VV) has been shown to improve respiratory function and reduce pulmonary histological damage compared to protective volume-controlled ventilation (VCV) in different models of lung injury induced by endotoxin, surfactant depletion by saline lavage, and hydrochloric acid. However, no study has compared the biological impact of VV vs. VCV in lung ischemia-reperfusion injury, which has a complex pathophysiology different from that of other experimental models. Thirty-six animals were randomly assigned to one of two groups: (1) ischemia-reperfusion (IR), in which the left pulmonary hilum was completely occluded and released after 30 min; and (2) Sham, in which animals underwent the same surgical manipulation but without hilar clamping. Immediately after surgery, the left (IR-injured) and right (contralateral) lungs from 6 animals per group were removed, and served as non-ventilated group (NV) for molecular biology analysis. IR and Sham groups were further randomized to one of two ventilation strategies: VCV ( n = 6/group) [tidal volume (V T ) = 6 mL/kg, positive end-expiratory pressure (PEEP) = 2 cmH 2 O, fraction of inspired oxygen (FiO 2 ) = 0.4]; or VV, which was applied on a breath-to-breath basis as a sequence of randomly generated V T values ( n = 1200; mean V T = 6 mL/kg), with a 30% coefficient of variation. After 5 min of ventilation and at the end of a 2-h period (Final), respiratory system mechanics and arterial blood gases were measured. At Final, lungs were removed for histological and molecular biology analyses. Respiratory system elastance and alveolar collapse were lower in VCV than VV (mean ± SD, VCV 3.6 ± 1.3 cmH 2 0/ml and 2.0 ± 0.8 cmH 2 0/ml, p = 0.005; median [interquartile range], VCV 20.4% [7.9-33.1] and VV 5.4% [3.1-8.8], p = 0.04, respectively). In left lungs of IR animals, VCV increased the expression of interleukin-6 and

  5. Variable Ventilation Improved Respiratory System Mechanics and Ameliorated Pulmonary Damage in a Rat Model of Lung Ischemia-Reperfusion

    PubMed Central

    Soluri-Martins, André; Moraes, Lillian; Santos, Raquel S.; Santos, Cintia L.; Huhle, Robert; Capelozzi, Vera L.; Pelosi, Paolo; Silva, Pedro L.; de Abreu, Marcelo Gama; Rocco, Patricia R. M.

    2017-01-01

    Lung ischemia-reperfusion injury remains a major complication after lung transplantation. Variable ventilation (VV) has been shown to improve respiratory function and reduce pulmonary histological damage compared to protective volume-controlled ventilation (VCV) in different models of lung injury induced by endotoxin, surfactant depletion by saline lavage, and hydrochloric acid. However, no study has compared the biological impact of VV vs. VCV in lung ischemia-reperfusion injury, which has a complex pathophysiology different from that of other experimental models. Thirty-six animals were randomly assigned to one of two groups: (1) ischemia-reperfusion (IR), in which the left pulmonary hilum was completely occluded and released after 30 min; and (2) Sham, in which animals underwent the same surgical manipulation but without hilar clamping. Immediately after surgery, the left (IR-injured) and right (contralateral) lungs from 6 animals per group were removed, and served as non-ventilated group (NV) for molecular biology analysis. IR and Sham groups were further randomized to one of two ventilation strategies: VCV (n = 6/group) [tidal volume (VT) = 6 mL/kg, positive end-expiratory pressure (PEEP) = 2 cmH2O, fraction of inspired oxygen (FiO2) = 0.4]; or VV, which was applied on a breath-to-breath basis as a sequence of randomly generated VT values (n = 1200; mean VT = 6 mL/kg), with a 30% coefficient of variation. After 5 min of ventilation and at the end of a 2-h period (Final), respiratory system mechanics and arterial blood gases were measured. At Final, lungs were removed for histological and molecular biology analyses. Respiratory system elastance and alveolar collapse were lower in VCV than VV (mean ± SD, VCV 3.6 ± 1.3 cmH20/ml and 2.0 ± 0.8 cmH20/ml, p = 0.005; median [interquartile range], VCV 20.4% [7.9–33.1] and VV 5.4% [3.1–8.8], p = 0.04, respectively). In left lungs of IR animals, VCV increased the expression of interleukin-6 and intercellular

  6. Evidence-based practice: use of the ventilator bundle to prevent ventilator-associated pneumonia.

    PubMed

    Tolentino-DelosReyes, Arlene F; Ruppert, Susan D; Shiao, Shyang-Yun Pamela K

    2007-01-01

    To examine critical care nurses' knowledge about the use of the ventilator bundle to prevent ventilator-associated pneumonia. Published reports were reviewed for current evidence on the use of the ventilator bundle to prevent ventilator-associated pneumonia, and education sessions were held to present the findings to 61 nurses in coronary care and surgical intensive care units. Changes in the nurses' knowledge were evaluated by using a 10-item test, given both before and after the sessions. Changes in the nurses' practices related to ventilator-associated pneumonia, including elevation of the head of the bed to 30 degrees to 45 degrees , were observed in 99 intubated patients. After the education sessions, the nurses performed better on 8 of the 10 items tested (P from .03 to <.001). The areas of most significant improvement were elevation of the head of the bed (P < .001), charting of the elevation of the head of the bed (P= .009), oral care (P= .009), checking of the nasogastric tube for residual volume (P = .008), washing of hands before contact with patients (P < .001), and limiting the wearing of rings (P < .001) and nail polish (P = .04). Even after the education sessions, the nurses' compliance with hand-washing recommendations before contact with patients was low, though statistically some improvement was apparent. Contraindications to elevation of the head of the bed did not appear to affect the nurses' practices (P= .38). Education sessions designed to inform nurses about the ventilator bundle and its use to prevent ventilator-associated pneumonia have a significant effect on participants' knowledge and subsequent clinical practice.

  7. Accuracy and time requirements of a bar-code inventory system for medical supplies.

    PubMed

    Hanson, L B; Weinswig, M H; De Muth, J E

    1988-02-01

    The effects of implementing a bar-code system for issuing medical supplies to nursing units at a university teaching hospital were evaluated. Data on the time required to issue medical supplies to three nursing units at a 480-bed, tertiary-care teaching hospital were collected (1) before the bar-code system was implemented (i.e., when the manual system was in use), (2) one month after implementation, and (3) four months after implementation. At the same times, the accuracy of the central supply perpetual inventory was monitored using 15 selected items. One-way analysis of variance tests were done to determine any significant differences between the bar-code and manual systems. Using the bar-code system took longer than using the manual system because of a significant difference in the time required for order entry into the computer. Multiple-use requirements of the central supply computer system made entering bar-code data a much slower process. There was, however, a significant improvement in the accuracy of the perpetual inventory. Using the bar-code system for issuing medical supplies to the nursing units takes longer than using the manual system. However, the accuracy of the perpetual inventory was significantly improved with the implementation of the bar-code system.

  8. Impact of Operating Rules on Planning Capacity Expansion of Urban Water Supply Systems

    NASA Astrophysics Data System (ADS)

    de Neufville, R.; Galelli, S.; Tian, X.

    2017-12-01

    This study addresses the impact of operating rules on capacity planning of urban water supply systems. The continuous growth of metropolitan areas represents a major challenge for water utilities, which often rely on industrial water supply (e.g., desalination, reclaimed water) to complement natural resources (e.g., reservoirs). These additional sources increase the reliability of supply, equipping operators with additional means to hedge against droughts. How do their rules for using industrial water supply impact the performance of water supply system? How might it affect long-term plans for capacity expansion? Possibly significantly, as demonstrated by the analysis of the operations and planning of a water supply system inspired by Singapore. Our analysis explores the system dynamics under multiple inflow and management scenarios to understand the extent to which alternative operating rules for the use of industrial water supply affect system performance. Results first show that these operating rules can have significant impact on the variability in system performance (e.g., reliability, energy use) comparable to that of hydro-climatological conditions. Further analyses of several capacity expansion exercises—based on our original hydrological and management scenarios—show that operating rules significantly affect the timing and magnitude of critical decisions, such as the construction of new desalination plants. These results have two implications: Capacity expansion analysis should consider the effect of a priori uncertainty about operating rules; and operators should consider how their flexibility in operating rules can affect their perceived need for capacity.

  9. TU-A-12A-02: Novel Lung Ventilation Imaging with Single Energy CT After Single Inhalation of Xenon: Comparison with SPECT Ventilation Images

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Negahdar, M; Yamamoto, T; Shultz, D

    Purpose: We propose a novel lung functional imaging method to determine the spatial distribution of xenon (Xe) gas in a single inhalation as a measure of regional ventilation. We compare Xe-CT ventilation to single-photon emission CT (SPECT) ventilation, which is the current clinical reference. Regional lung ventilation information may be useful for the diagnosis and monitoring of pulmonary diseases such as COPD, radiotherapy planning, and assessing the progression of toxicity after radiation therapy. Methods: In an IRB-approved clinical study, Xe-CT and SPECT ventilation scans were acquired for three patients including one patient with severe emphysema and two lung cancer patientsmore » treated with radiotherapy. For Xe- CT, we acquired two breath-hold single energy CT images of the entire lung with inspiration of 100% O2 and a mixture of 70% Xe and 30% O2, respectively. A video biofeedback system was used to achieve reproducible breath-holds. We used deformable image registration to align the breathhold images with each other to accurately subtract them, producing a map of the distribution of Xe as a surrogate of lung ventilation. We divided each lung into twelve parts and correlated the Hounsfield unit (HU) enhancement at each part with the SPECT ventilation count of the corresponding part of the lung. Results: The mean of the Pearson linear correlation coefficient values between the Xe-CT and ventilation SPECT count for all three patients were 0.62 (p<0.01). The Xe-CT image had a higher resolution than SPECT, and did not show central airway deposition artifacts that were present in the SPECT image. Conclusion: We developed a rapid, safe, clinically practical, and potentially widely accessible method for regional lung functional imaging. We demonstrated strong correlations between the Xe-CT ventilation image and SPECT ventilation image as the clinical reference. This ongoing study will investigate more patients to confirm this finding.« less

  10. International Space Station Crew Quarters Ventilation and Acoustic Design Implementation

    NASA Technical Reports Server (NTRS)

    Broyan, James L., Jr.; Cady, Scott M; Welsh, David A.

    2010-01-01

    The International Space Station (ISS) United States Operational Segment has four permanent rack sized ISS Crew Quarters (CQs) providing a private crew member space. The CQs use Node 2 cabin air for ventilation/thermal cooling, as opposed to conditioned ducted air-from the ISS Common Cabin Air Assembly (CCAA) or the ISS fluid cooling loop. Consequently, CQ can only increase the air flow rate to reduce the temperature delta between the cabin and the CQ interior. However, increasing airflow causes increased acoustic noise so efficient airflow distribution is an important design parameter. The CQ utilized a two fan push-pull configuration to ensure fresh air at the crew member's head position and reduce acoustic exposure. The CQ ventilation ducts are conduits to the louder Node 2 cabin aisle way which required significant acoustic mitigation controls. The CQ interior needs to be below noise criteria curve 40 (NC-40). The design implementation of the CQ ventilation system and acoustic mitigation are very inter-related and require consideration of crew comfort balanced with use of interior habitable volume, accommodation of fan failures, and possible crew uses that impact ventilation and acoustic performance. Each CQ required 13% of its total volume and approximately 6% of its total mass to reduce acoustic noise. This paper illustrates the types of model analysis, assumptions, vehicle interactions, and trade-offs required for CQ ventilation and acoustics. Additionally, on-orbit ventilation system performance and initial crew feedback is presented. This approach is applicable to any private enclosed space that the crew will occupy.

  11. Ventilator Dependence Risk Score for the Prediction of Prolonged Mechanical Ventilation in Patients Who Survive Sepsis/Septic Shock with Respiratory Failure.

    PubMed

    Chang, Ya-Chun; Huang, Kuo-Tung; Chen, Yu-Mu; Wang, Chin-Chou; Wang, Yi-Hsi; Tseng, Chia-Cheng; Lin, Meng-Chih; Fang, Wen-Feng

    2018-04-04

    We intended to develop a scoring system to predict mechanical ventilator dependence in patients who survive sepsis/septic shock with respiratory failure. This study evaluated 251 adult patients in medical intensive care units (ICUs) between August 2013 to October 2015, who had survived for over 21 days and received aggressive treatment. The risk factors for ventilator dependence were determined. We then constructed a ventilator dependence (VD) risk score using the identified risk factors. The ventilator dependence risk score was calculated as the sum of the following four variables after being adjusted by proportion to the beta coefficient. We assigned a history of previous stroke, a score of one point, platelet count less than 150,000/μL a score of one point, pH value less than 7.35 a score of two points, and the fraction of inspired oxygen on admission day 7 over 39% as two points. The area under the curve in the derivation group was 0.725 (p < 0.001). We then applied the VD risk score for validation on 175 patients. The area under the curve in the validation group was 0.658 (p = 0.001). VD risk score could be applied to predict prolonged mechanical ventilation in patients who survive sepsis/septic shock.

  12. Impact of ventilation systems and energy savings in a building on the mechanisms governing the indoor radon activity concentration.

    PubMed

    Collignan, Bernard; Powaga, Emilie

    2017-11-23

    For a given radon potential in the ground and a given building, the parameters affecting the indoor radon activity concentration (IRnAC) are indoor depressurization of a building and its air change rate. These parameters depend mainly on the building characteristics, such as airtightness, and on the nature and performances of the ventilation system. This study involves a numerical sensitivity assessment of the indoor environmental conditions on the IRnAC in buildings. A numerical ventilation model has been adapted to take into account the effects of variations in the indoor environmental conditions (depressurization and air change rate) on the radon entry rate and on the IRnAC. In the context of the development of a policy to reduce energy consumption in a building, the results obtained showed that IRnAC could be strongly affected by variations in the air permeability of the building associated with the ventilation regime. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Variable tidal volumes improve lung protective ventilation strategies in experimental lung injury.

    PubMed

    Spieth, Peter M; Carvalho, Alysson R; Pelosi, Paolo; Hoehn, Catharina; Meissner, Christoph; Kasper, Michael; Hübler, Matthias; von Neindorff, Matthias; Dassow, Constanze; Barrenschee, Martina; Uhlig, Stefan; Koch, Thea; de Abreu, Marcelo Gama

    2009-04-15

    Noisy ventilation with variable Vt may improve respiratory function in acute lung injury. To determine the impact of noisy ventilation on respiratory function and its biological effects on lung parenchyma compared with conventional protective mechanical ventilation strategies. In a porcine surfactant depletion model of lung injury, we randomly combined noisy ventilation with the ARDS Network protocol or the open lung approach (n = 9 per group). Respiratory mechanics, gas exchange, and distribution of pulmonary blood flow were measured at intervals over a 6-hour period. Postmortem, lung tissue was analyzed to determine histological damage, mechanical stress, and inflammation. We found that, at comparable minute ventilation, noisy ventilation (1) improved arterial oxygenation and reduced mean inspiratory peak airway pressure and elastance of the respiratory system compared with the ARDS Network protocol and the open lung approach, (2) redistributed pulmonary blood flow to caudal zones compared with the ARDS Network protocol and to peripheral ones compared with the open lung approach, (3) reduced histological damage in comparison to both protective ventilation strategies, and (4) did not increase lung inflammation or mechanical stress. Noisy ventilation with variable Vt and fixed respiratory frequency improves respiratory function and reduces histological damage compared with standard protective ventilation strategies.

  14. The impact of a ventilator bundle on preventing ventilator-associated pneumonia: a multicenter study.

    PubMed

    Eom, Joong Sik; Lee, Mi-Suk; Chun, Hee-Kyung; Choi, Hee Jung; Jung, Sun-Young; Kim, Yeon-Sook; Yoon, Seon Jin; Kwak, Yee Gyung; Oh, Gang-Bok; Jeon, Min-Hyok; Park, Sun-Young; Koo, Hyun-Sook; Ju, Young-Su; Lee, Jin Seo

    2014-01-01

    For prevention of ventilator-associated pneumonia (VAP), a bundle approach was applied to patients receiving mechanical ventilation in intensive care units. The incidence of VAP and the preventive efficacy of the VAP bundle were investigated. A quasi-experimental study was conducted in adult intensive care units of 6 university hospitals with similar VAP rates. We implemented the VAP bundle between March 2011 and June 2011, then compared the rate of VAP after implementation of the VAP bundle with the rate in the previous 8 months. Our ventilator bundle included head of bed elevation, peptic ulcer disease prophylaxis, deep venous thrombosis prophylaxis, and oral decontamination with chlorhexidine 0.12%. Continuous aspiration of subglottic secretions was an option. Implementation of the VAP bundle reduced the VAP rate from a mean of 4.08 cases per 1,000 ventilator-days to 1.16 cases per 1,000 ventilator-days. The incidence density ratio (rate) was 0.28 (95% confidence interval, 0.275-0.292). Implementing the appropriate VAP bundle significantly decreased the incidence of VAP in patients with mechanical ventilation. Copyright © 2014 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

  15. Fungal volatiles associated with moldy grain in ventilated and non-ventilated bin-stored wheat.

    PubMed

    Sinha, R N; Tuma, D; Abramson, D; Muir, W E

    1988-01-01

    The fungal odor compounds 3-methyl-1-butanol, 1-octen-3-ol and 3-octanone were monitored in nine experimental bins in Winnipeg, Manitoba containing a hard red spring wheat during the autumn, winter and summer seasons of 1984-85. Quality changes were associated with seed-borne microflora and moisture content in both ventilated and non-ventilated bins containing wheat of 15.6 and 18.2% initial moisture content. All three odor compounds occurred in considerably greater amounts in bulk wheat in non-ventilated than in ventilated bins, particularly in those with wheat having 18.2% moisture content. The presence of these compounds usually coincided with infection of the seeds by the fungi Alternaria alternata (Fr.) Keissler, Aspergillus repens DeBarry, A. versicolor (Vuill.) Tiraboschi, Penicillium crustosum Thom, P. oxalicum Currie and Thom, P. aurantiogriesum Dierckx, and P. citrinum Thom. High production of all three odor compounds in damp wheat stored in non-ventilated bins was associated with heavy fungal infection of the seeds and reduction in seed germinability. High initial moisture content of the harvested grain accelerated the production of all three fungal volatiles in non-ventilated bins.

  16. Experimental evaluation of the Skylab orbital workshop ventilation system concept

    NASA Technical Reports Server (NTRS)

    Allums, S. L.; Hastings, L. J.; Ralston, J. T.

    1972-01-01

    Extensive testing was conducted to evaluate the Orbital Workshop ventilation concept. Component tests were utilized to determine the relationship between operating characteristics at 1 and 0.34 atm. System tests were conducted at 1 atm within the Orbital Workshop full-scale mockup to assess delivered volumetric flow rate and compartment air velocities. Component tests with the Anemostat circular diffusers (plenum- and duct-mounted) demonstrated that the diffuser produced essentially equivalent airflow patterns and velocities in 1- and 0.34-atm environments. The tests also showed that the pressure drop across the diffuser could be scaled from 1 to 0.34 atm using the atmosphere pressure ratio. Fan tests indicated that the performance of a multiple, parallel-mounted fan cluster could be predicted by summing the single-fan flow rates at a given delta P.

  17. Mechanical ventilation for severe asthma.

    PubMed

    Leatherman, James

    2015-06-01

    Acute exacerbations of asthma can lead to respiratory failure requiring ventilatory assistance. Noninvasive ventilation may prevent the need for endotracheal intubation in selected patients. For patients who are intubated and undergo mechanical ventilation, a strategy that prioritizes avoidance of ventilator-related complications over correction of hypercapnia was first proposed 30 years ago and has become the preferred approach. Excessive pulmonary hyperinflation is a major cause of hypotension and barotrauma. An appreciation of the key determinants of hyperinflation is essential to rational ventilator management. Standard therapy for patients with asthma undergoing mechanical ventilation consists of inhaled bronchodilators, corticosteroids, and drugs used to facilitate controlled hypoventilation. Nonconventional interventions such as heliox, general anesthesia, bronchoscopy, and extracorporeal life support have also been advocated for patients with fulminant asthma but are rarely necessary. Immediate mortality for patients who are mechanically ventilated for acute severe asthma is very low and is often associated with out-of-hospital cardiorespiratory arrest before intubation. However, patients who have been intubated for severe asthma are at increased risk for death from subsequent exacerbations and must be managed accordingly in the outpatient setting.

  18. Wind Extraction for Natural Ventilation

    NASA Astrophysics Data System (ADS)

    Fagundes, Tadeu; Yaghoobian, Neda; Kumar, Rajan; Ordonez, Juan

    2017-11-01

    Due to the depletion of energy resources and the environmental impact of pollution and unsustainable energy resources, energy consumption has become one of the main concerns in our rapidly growing world. Natural ventilation, a traditional method to remove anthropogenic and solar heat gains, proved to be a cost-effective, alternative method to mechanical ventilation. However, while natural ventilation is simple in theory, its detailed design can be a challenge, particularly for wind-driven ventilation, which its performance highly involves the buildings' form, surrounding topography, turbulent flow characteristics, and climate. One of the main challenges with wind-driven natural ventilation schemes is due to the turbulent and unpredictable nature of the wind around the building that impose complex pressure loads on the structure. In practice, these challenges have resulted in founding the natural ventilation mainly on buoyancy (rather than the wind), as the primary force. This study is the initial step for investigating the physical principals of wind extraction over building walls and investigating strategies to reduce the dependence of the wind extraction on the incoming flow characteristics and the target building form.

  19. Air compressor battery duration with mechanical ventilation in a field anesthesia machine.

    PubMed

    Szpisjak, Dale F; Giberman, Anthony A

    2015-05-01

    Compressed air to power field anesthesia machine ventilators may be supplied by air compressor with battery backup. This study determined the battery duration when the compPAC ventilator's air compressor was powered by NiCd battery to ventilate the Vent Aid Training Test Lung modeling high (HC = 0.100 L/cm H2O) and low (LC = 0.020 L/cm H2O) pulmonary compliance. Target tidal volumes (VT) were 500, 750, and 1,000 mL. Respiratory rate = 10 bpm, inspiratory-to-expiratory time ratio = 1:2, and fresh gas flow = 1 L/min air. N = 5 in each group. Control limits were determined from the first 150 minutes of battery power for each run and lower control limit = mean VT - 3SD. Battery depletion occurred when VT was below the lower control limit. Battery duration ranged from 185.8 (±3.2) minutes in the LC-1000 group to 233.3 (±3.6) minutes in the HC-750 group. Battery duration of the LC-1000 group was less than all others (p = 0.027). The differences among the non-LC-1000 groups were not clinically significant. Reprint & Copyright © 2015 Association of Military Surgeons of the U.S.

  20. Comparison between conventional and protective one-lung ventilation for ventilator-assisted thoracic surgery.

    PubMed

    Ahn, H J; Kim, J A; Yang, M; Shim, W S; Park, K J; Lee, J J

    2012-09-01

    Recent papers suggest protective ventilation (PV) as a primary ventilation strategy during one-lung ventilation (OLV) to reduce postoperative pulmonary morbidity. However, data regarding the advantage of the PV strategy in patients with normal preoperative pulmonary function are inconsistent, especially in the case of minimally invasive thoracic surgery. Therefore we compared conventional OLV (VT 10 ml/kg, FiO2 1.0, zero PEEP) to protective OLV (VT 6 ml/kg, FiO2 0.5, PEEP 5 cmH2O) in patients with normal preoperative pulmonary function tests undergoing video-assisted thoracic surgery. Oxygenation, respiratory mechanics, plasma interleukin-6 and malondialdehyde levels were measured at baseline, 15 and 60 minutes after OLV and 15 minutes after restoration of two-lung ventilation. PaO2 and PaO2/FiO2 were higher in conventional OLV than in protective OLV (P<0.001). Interleukin-6 and malondialdehyde increased over time in both groups (P<0.05); however, the magnitudes of increase were not different between the groups. Postoperatively there were no differences in the number of patients with PaO2/FiO2<300 mmHg or abnormalities on chest radiography. Protective ventilation did not provide advantages over conventional ventilation for video-assisted thoracic surgery in this group of patients with normal lung function.

  1. 46 CFR 129.540 - Remote stopping-systems on OSVs of 100 or more gross tons.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) OFFSHORE SUPPLY VESSELS ELECTRICAL INSTALLATIONS Miscellaneous Electrical Systems § 129.540 Remote stopping... subpart 111.103 of this chapter: (1) For each propulsion unit, in the pilothouse. (2) For each discharge pump for bilge slop or dirty oil, at the deck discharge. (3) For each powered ventilation system...

  2. Mechanical ventilation interacts with endotoxemia to induce extrapulmonary organ dysfunction

    PubMed Central

    O'Mahony, D Shane; Liles, W Conrad; Altemeier, William A; Dhanireddy, Shireesha; Frevert, Charles W; Liggitt, Denny; Martin, Thomas R; Matute-Bello, Gustavo

    2006-01-01

    Introduction Multiple organ dysfunction syndrome (MODS) is a common complication of sepsis in mechanically ventilated patients with acute respiratory distress syndrome, but the links between mechanical ventilation and MODS are unclear. Our goal was to determine whether a minimally injurious mechanical ventilation strategy synergizes with low-dose endotoxemia to induce the activation of pro-inflammatory pathways in the lungs and in the systemic circulation, resulting in distal organ dysfunction and/or injury. Methods We administered intraperitoneal Escherichia coli lipopolysaccharide (LPS; 1 μg/g) to C57BL/6 mice, and 14 hours later subjected the mice to 6 hours of mechanical ventilation with tidal volumes of 10 ml/kg (LPS + MV). Comparison groups received ventilation but no LPS (MV), LPS but no ventilation (LPS), or neither LPS nor ventilation (phosphate-buffered saline; PBS). Results Myeloperoxidase activity and the concentrations of the chemokines macrophage inflammatory protein-2 (MIP-2) and KC were significantly increased in the lungs of mice in the LPS + MV group, in comparison with mice in the PBS group. Interestingly, permeability changes across the alveolar epithelium and histological changes suggestive of lung injury were minimal in mice in the LPS + MV group. However, despite the minimal lung injury, the combination of mechanical ventilation and LPS resulted in chemical and histological evidence of liver and kidney injury, and this was associated with increases in the plasma concentrations of KC, MIP-2, IL-6, and TNF-α. Conclusion Non-injurious mechanical ventilation strategies interact with endotoxemia in mice to enhance pro-inflammatory mechanisms in the lungs and promote extra-pulmonary end-organ injury, even in the absence of demonstrable acute lung injury. PMID:16995930

  3. Mechanical ventilation in abdominal surgery.

    PubMed

    Futier, E; Godet, T; Millot, A; Constantin, J-M; Jaber, S

    2014-01-01

    One of the key challenges in perioperative care is to reduce postoperative morbidity and mortality. Patients who develop postoperative morbidity but survive to leave hospital have often reduced functional independence and long-term survival. Mechanical ventilation provides a specific example that may help us to shift thinking from treatment to prevention of postoperative complications. Mechanical ventilation in patients undergoing surgery has long been considered only as a modality to ensure gas exchange while allowing maintenance of anesthesia with delivery of inhaled anesthetics. Evidence is accumulating, however, suggesting an association between intraoperative mechanical ventilation strategy and postoperative pulmonary function and clinical outcome in patients undergoing abdominal surgery. Non-protective ventilator settings, especially high tidal volume (VT) (>10-12mL/kg) and the use of very low level of positive end-expiratory pressure (PEEP) (PEEP<5cmH2O) or no PEEP, may cause alveolar overdistension and repetitive tidal recruitment leading to ventilator-associated lung injury in patients with healthy lungs. Stimulated by previous findings in patients with acute respiratory distress syndrome, the use of lower tidal volume ventilation is becoming increasingly more common in the operating room. However, lowering tidal volume, though important, is only part of the overall multifaceted approach of lung protective mechanical ventilation. In this review, we aimed at providing the most recent and relevant clinical evidence regarding the use of mechanical ventilation in patients undergoing abdominal surgery. Copyright © 2014 Société française d’anesthésie et de réanimation (Sfar). Published by Elsevier SAS. All rights reserved.

  4. Ventilation noise and its effects on annoyance and performance

    NASA Astrophysics Data System (ADS)

    Landstrom, Ulf

    2004-05-01

    In almost every room environment, ventilation acts as a more or less prominent part of the noise exposure. The contribution to the overall sound environment is a question not only of the way in which the ventilation system itself functions, but also a question of the prominence of other contemporary sound sources such as speech, equipment, machines, and external noises. Hazardous effects due to ventilation noise are most prominent in offices, hospitals, control rooms, classrooms, conference rooms, and other types of silent areas. The effects evoked by ventilation noise have also been found to be related to the type of activity being conducted. Annoyance and performance thus not only seemed to be linked to the physical character of exposure, i.e., noise level, frequency characteristics, and length of exposure, but also mental and manual activity, complexity, and monotony of the work. The effects can be described in terms of annoyance, discomfort, and fatigue, with consequences on performance and increased mental load. The silent areas where ventilation noise may be most frequently experienced are often synonymous with areas and activities most sensitive to the exposure.

  5. Design and application of a new control system for tokamak ECRH power supply

    NASA Astrophysics Data System (ADS)

    Hao, Xu; Zhang, Jian; Huang, Yiyun

    2016-03-01

    The biggest challenge of designing and building tokamak electron cyclotron resonance heating (ECRH) pulse step modulation (PSM) power supply is satisfying its required output voltage rising time to be less than 100 µs while suppressing the voltage overshoot to be no more than 1%. To fulfill the two requirements, a new control strategy with startup time in microsecond range is proposed in this paper, and a new control system to realize the control strategy is introduced. The control system was built and tested on 60 kV/50 A ECRH power supply. The experimental results indicate that the control system can restrain the overshoot effectively, increase response speed, and obviously improve the dynamic characteristics of the PSM power supply system. Thus, the proposed control system helps the PSM power supply to meet the design specifications.

  6. Comparison between conventional protective mechanical ventilation and high-frequency oscillatory ventilation associated with the prone position.

    PubMed

    Fioretto, José Roberto; Klefens, Susiane Oliveira; Pires, Rafaelle Fernandes; Kurokawa, Cilmery Suemi; Carpi, Mario Ferreira; Bonatto, Rossano César; Moraes, Marcos Aurélio; Ronchi, Carlos Fernando

    2017-01-01

    To compare the effects of high-frequency oscillatory ventilation and conventional protective mechanical ventilation associated with the prone position on oxygenation, histology and pulmonary oxidative damage in an experimental model of acute lung injury. Forty-five rabbits with tracheostomy and vascular access were underwent mechanical ventilation. Acute lung injury was induced by tracheal infusion of warm saline. Three experimental groups were formed: healthy animals + conventional protective mechanical ventilation, supine position (Control Group; n = 15); animals with acute lung injury + conventional protective mechanical ventilation, prone position (CMVG; n = 15); and animals with acute lung injury + high-frequency oscillatory ventilation, prone position (HFOG; n = 15). Ten minutes after the beginning of the specific ventilation of each group, arterial gasometry was collected, with this timepoint being called time zero, after which the animal was placed in prone position and remained in this position for 4 hours. Oxidative stress was evaluated by the total antioxidant performance assay. Pulmonary tissue injury was determined by histopathological score. The level of significance was 5%. Both groups with acute lung injury showed worsening of oxygenation after induction of injury compared with the Control Group. After 4 hours, there was a significant improvement in oxygenation in the HFOG group compared with CMVG. Analysis of total antioxidant performance in plasma showed greater protection in HFOG. HFOG had a lower histopathological lesion score in lung tissue than CMVG. High-frequency oscillatory ventilation, associated with prone position, improves oxygenation and attenuates oxidative damage and histopathological lung injury compared with conventional protective mechanical ventilation.

  7. Comparison between conventional protective mechanical ventilation and high-frequency oscillatory ventilation associated with the prone position

    PubMed Central

    Fioretto, José Roberto; Klefens, Susiane Oliveira; Pires, Rafaelle Fernandes; Kurokawa, Cilmery Suemi; Carpi, Mario Ferreira; Bonatto, Rossano César; Moraes, Marcos Aurélio; Ronchi, Carlos Fernando

    2017-01-01

    Objective To compare the effects of high-frequency oscillatory ventilation and conventional protective mechanical ventilation associated with the prone position on oxygenation, histology and pulmonary oxidative damage in an experimental model of acute lung injury. Methods Forty-five rabbits with tracheostomy and vascular access were underwent mechanical ventilation. Acute lung injury was induced by tracheal infusion of warm saline. Three experimental groups were formed: healthy animals + conventional protective mechanical ventilation, supine position (Control Group; n = 15); animals with acute lung injury + conventional protective mechanical ventilation, prone position (CMVG; n = 15); and animals with acute lung injury + high-frequency oscillatory ventilation, prone position (HFOG; n = 15). Ten minutes after the beginning of the specific ventilation of each group, arterial gasometry was collected, with this timepoint being called time zero, after which the animal was placed in prone position and remained in this position for 4 hours. Oxidative stress was evaluated by the total antioxidant performance assay. Pulmonary tissue injury was determined by histopathological score. The level of significance was 5%. Results Both groups with acute lung injury showed worsening of oxygenation after induction of injury compared with the Control Group. After 4 hours, there was a significant improvement in oxygenation in the HFOG group compared with CMVG. Analysis of total antioxidant performance in plasma showed greater protection in HFOG. HFOG had a lower histopathological lesion score in lung tissue than CMVG. Conclusion High-frequency oscillatory ventilation, associated with prone position, improves oxygenation and attenuates oxidative damage and histopathological lung injury compared with conventional protective mechanical ventilation. PMID:29236845

  8. Do submesoscale frontal processes ventilate the oxygen minimum zone off Peru?

    NASA Astrophysics Data System (ADS)

    Thomsen, S.; Kanzow, T.; Colas, F.; Echevin, V.; Krahmann, G.; Engel, A.

    2016-08-01

    The Peruvian upwelling system encompasses the most intense and shallowest oxygen minimum zone (OMZ) in the ocean. This system shows pronounced submesoscale activity like filaments and fronts. We carried out glider-based observations off Peru during austral summer 2013 to investigate whether submesoscale frontal processes ventilate the Peruvian OMZ. We present observational evidence for the subduction of highly oxygenated surface water in a submesoscale cold filament. The subduction event ventilates the oxycline but does not reach OMZ core waters. In a regional submesoscale-permitting model we study the pathways of newly upwelled water. About 50% of upwelled virtual floats are subducted below the mixed layer within 5 days emphasizing a hitherto unrecognized importance of subduction for the ventilation of the Peruvian oxycline.

  9. SU-F-J-219: Predicting Ventilation Change Due to Radiation Therapy: Dependency On Pre-RT Ventilation and Effort Correction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Patton, T; Du, K; Bayouth, J

    Purpose: Ventilation change caused by radiation therapy (RT) can be predicted using four-dimensional computed tomography (4DCT) and image registration. This study tested the dependency of predicted post-RT ventilation on effort correction and pre-RT lung function. Methods: Pre-RT and 3 month post-RT 4DCT images were obtained for 13 patients. The 4DCT images were used to create ventilation maps using a deformable image registration based Jacobian expansion calculation. The post-RT ventilation maps were predicted in four different ways using the dose delivered, pre-RT ventilation, and effort correction. The pre-RT ventilation and effort correction were toggled to determine dependency. The four different predictedmore » ventilation maps were compared to the post-RT ventilation map calculated from image registration to establish the best prediction method. Gamma pass rates were used to compare the different maps with the criteria of 2mm distance-to-agreement and 6% ventilation difference. Paired t-tests of gamma pass rates were used to determine significant differences between the maps. Additional gamma pass rates were calculated using only voxels receiving over 20 Gy. Results: The predicted post-RT ventilation maps were in agreement with the actual post-RT maps in the following percentage of voxels averaged over all subjects: 71% with pre-RT ventilation and effort correction, 69% with no pre-RT ventilation and effort correction, 60% with pre-RT ventilation and no effort correction, and 58% with no pre-RT ventilation and no effort correction. When analyzing only voxels receiving over 20 Gy, the gamma pass rates were respectively 74%, 69%, 65%, and 55%. The prediction including both pre- RT ventilation and effort correction was the only prediction with significant improvement over using no prediction (p<0.02). Conclusion: Post-RT ventilation is best predicted using both pre-RT ventilation and effort correction. This is the only prediction that provided a significant

  10. [Surveillance of drinking water supply systems on markets and in vehicles].

    PubMed

    Rädel, U; Puchert, W; Suchenwirth, R

    2007-03-01

    The new German Drinking Water Ordinance (TrinkwV 2001) demands that the requirements of water intended for human consumption be met up to the intrinsic tap, at which the water is used. This also applies to water supply systems for food trade aboard non-stationary facilities and in vehicles for commercial purposes. In contrast to stationary units for drinking water supply, the nonstationary units relocate and the responsibility changes with each public health authority agent. Therefore, a coordinated action between the federal states is desirable and necessary. The experience of the public health departments presents many non-compliant parameters of microbiology in water supply systems on markets and in vehicles. The development of practical and consistent recommendations for the surveillance of non-stationary units is required to give consistent standards to the users. The article gives a review about legal foundations and technical rules in order to define the drinking water supply systems on markets and in vehicles in compliance with the German Drinking Water Ordinance. Examples of laboratory results from different monitoring episodes from three federal states are shown.

  11. Effects of Multiple Ventilation Courses and Duration of Mechanical Ventilation on Respiratory Outcomes in Extremely Low-Birth-Weight Infants.

    PubMed

    Jensen, Erik A; DeMauro, Sara B; Kornhauser, Michael; Aghai, Zubair H; Greenspan, Jay S; Dysart, Kevin C

    2015-11-01

    Extubation failure is common in extremely preterm infants. The current paucity of data on the adverse long-term respiratory outcomes associated with reinitiation of mechanical ventilation prevents assessment of the risks and benefits of a trial of extubation in this population. To evaluate whether exposure to multiple courses of mechanical ventilation increases the risk of adverse respiratory outcomes before and after adjustment for the cumulative duration of mechanical ventilation. We performed a retrospective cohort study of extremely low-birth-weight (ELBW; birth weight <1000 g) infants born from January 1, 2006, through December 31, 2012, who were receiving mechanical ventilation. Analysis was conducted between November 2014 and February 2015. Data were obtained from the Alere Neonatal Database. The primary study exposures were the cumulative duration of mechanical ventilation and the number of ventilation courses. The primary outcome was bronchopulmonary dysplasia (BPD) among survivors. Secondary outcomes were death, use of supplemental oxygen at discharge, and tracheostomy. We identified 3343 ELBW infants, of whom 2867 (85.8%) survived to discharge. Among the survivors, 1695 (59.1%) were diagnosed as having BPD, 856 (29.9%) received supplemental oxygen at discharge, and 31 (1.1%) underwent tracheostomy. Exposure to a greater number of mechanical ventilation courses was associated with a progressive increase in the risk of BPD and use of supplemental oxygen at discharge. Compared with a single ventilation course, the adjusted odds ratios for BPD ranged from 1.88 (95% CI, 1.54-2.31) among infants with 2 ventilation courses to 3.81 (95% CI, 2.88-5.04) among those with 4 or more courses. After adjustment for the cumulative duration of mechanical ventilation, the odds of BPD were only increased among infants exposed to 4 or more ventilation courses (adjusted odds ratio, 1.44; 95% CI, 1.04-2.01). The number of ventilation courses was not associated with increased

  12. Mechanical ventilation during extracorporeal membrane oxygenation.

    PubMed

    Schmidt, Matthieu; Pellegrino, Vincent; Combes, Alain; Scheinkestel, Carlos; Cooper, D Jamie; Hodgson, Carol

    2014-01-21

    The timing of extracorporeal membrane oxygenation (ECMO) initiation and its outcome in the management of respiratory and cardiac failure have received considerable attention, but very little attention has been given to mechanical ventilation during ECMO. Mechanical ventilation settings in non-ECMO studies have been shown to have an effect on survival and may also have contributed to a treatment effect in ECMO trials. Protective lung ventilation strategies established for non-ECMO-supported respiratory failure patients may not be optimal for more severe forms of respiratory failure requiring ECMO support. The influence of positive end-expiratory pressure on the reduction of the left ventricular compliance may be a matter of concern for patients receiving ECMO support for cardiac failure. The objectives of this review were to describe potential mechanisms for lung injury during ECMO for respiratory or cardiac failure, to assess the possible benefits from the use of ultra-protective lung ventilation strategies and to review published guidelines and expert opinions available on mechanical ventilation-specific management of patients requiring ECMO, including mode and ventilator settings. Articles were identified through a detailed search of PubMed, Ovid, Cochrane databases and Google Scholar. Additional references were retrieved from the selected studies. Growing evidence suggests that mechanical ventilation settings are important in ECMO patients to minimize further lung damage and improve outcomes. An ultra-protective ventilation strategy may be optimal for mechanical ventilation during ECMO for respiratory failure. The effects of airway pressure on right and left ventricular afterload should be considered during venoarterial ECMO support of cardiac failure. Future studies are needed to better understand the potential impact of invasive mechanical ventilation modes and settings on outcomes.

  13. Mechanical ventilation during extracorporeal membrane oxygenation

    PubMed Central

    2014-01-01

    The timing of extracorporeal membrane oxygenation (ECMO) initiation and its outcome in the management of respiratory and cardiac failure have received considerable attention, but very little attention has been given to mechanical ventilation during ECMO. Mechanical ventilation settings in non-ECMO studies have been shown to have an effect on survival and may also have contributed to a treatment effect in ECMO trials. Protective lung ventilation strategies established for non-ECMO-supported respiratory failure patients may not be optimal for more severe forms of respiratory failure requiring ECMO support. The influence of positive end-expiratory pressure on the reduction of the left ventricular compliance may be a matter of concern for patients receiving ECMO support for cardiac failure. The objectives of this review were to describe potential mechanisms for lung injury during ECMO for respiratory or cardiac failure, to assess the possible benefits from the use of ultra-protective lung ventilation strategies and to review published guidelines and expert opinions available on mechanical ventilation-specific management of patients requiring ECMO, including mode and ventilator settings. Articles were identified through a detailed search of PubMed, Ovid, Cochrane databases and Google Scholar. Additional references were retrieved from the selected studies. Growing evidence suggests that mechanical ventilation settings are important in ECMO patients to minimize further lung damage and improve outcomes. An ultra-protective ventilation strategy may be optimal for mechanical ventilation during ECMO for respiratory failure. The effects of airway pressure on right and left ventricular afterload should be considered during venoarterial ECMO support of cardiac failure. Future studies are needed to better understand the potential impact of invasive mechanical ventilation modes and settings on outcomes. PMID:24447458

  14. 46 CFR 194.15-5 - Ventilation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CONTROL OF EXPLOSIVES AND OTHER HAZARDOUS MATERIALS Chemistry Laboratory and Scientific Laboratory § 194... be equipped with acceptable flame screens. (b) Chemical laboratories shall be equipped with power...) Ventilation of air conditioning systems serving the chemical laboratory shall be designed so that air cannot...

  15. 46 CFR 194.15-5 - Ventilation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... CONTROL OF EXPLOSIVES AND OTHER HAZARDOUS MATERIALS Chemistry Laboratory and Scientific Laboratory § 194... be equipped with acceptable flame screens. (b) Chemical laboratories shall be equipped with power...) Ventilation of air conditioning systems serving the chemical laboratory shall be designed so that air cannot...

  16. Lung-protective ventilation in abdominal surgery.

    PubMed

    Futier, Emmanuel; Jaber, Samir

    2014-08-01

    To provide the most recent and relevant clinical evidence regarding the use of prophylactic lung-protective mechanical ventilation in abdominal surgery. Evidence is accumulating, suggesting an association between intraoperative mechanical ventilation strategy and postoperative pulmonary complications in patients undergoing abdominal surgery. Nonprotective ventilator settings, especially high tidal volume (>10-12 ml/kg), very low level of positive end-expiratory pressure (PEEP, <5 cm H2O), or no PEEP, may cause alveolar overdistension and repetitive tidal recruitment leading to ventilator-associated lung injury in patients with healthy lungs. Stimulated by the previous findings in patients with acute respiratory distress syndrome, the use of lower tidal volume ventilation is becoming increasingly more common in the operating room. However, lowering tidal volume, though important, is only part of the overall multifaceted approach of lung-protective mechanical ventilation. Recent data provide compelling evidence that prophylactic lung-protective mechanical ventilation using lower tidal volume (6-8 ml/kg of predicted body weight), moderate PEEP (6-8 cm H2O), and recruitment maneuvers is associated with improved functional or physiological and clinical postoperative outcome in patients undergoing abdominal surgery. The use of prophylactic lung-protective ventilation can help in improving the postoperative outcome.

  17. [Mechanical ventilation in acute asthma crisis].

    PubMed

    Barbas, Carmen Sílvia Valente; Pinheiro, Bruno do Valle; Vianna, Arthur; Magaldi, Ricardo; Casati, Ana; José, Anderson; Okamoto, Valdelis Novis

    2007-06-01

    The II Brazilian Consensus Conference on Mechanical Ventilation was published in 2000. Knowledge on the field of mechanical ventilation evolved rapidly since then, with the publication of numerous clinical studies with potential impact on the ventilatory management of critically ill patients. Moreover, the evolving concept of evidence - based medicine determined the grading of clinical recommendations according to the methodological value of the studies on which they are based. This explicit approach has broadened the understanding and adoption of clinical recommendations. For these reasons, AMIB - Associação de Medicina Intensiva Brasileira and SBPT - Sociedade Brasileira de Pneumologia e Tisiologia - decided to update the recommendations of the II Brazilian Consensus. Mechanical ventilation in the asthma attack has been one of the updated topics. Describe the most important topics on the mechanical ventilation during the asthma attack and suggest the main therapeutic approaches. Systematic review of the published literature and gradation of the studies in levels of evidence, using the key words "mechanical ventilation" and "asthma". We present recommendations on the ventilatory modes and settings to be adopted when ventilating a patient during an asthma attack, as well as the recommended monitoring. Alternative ventilation techniques are also presented. Protective ventilatory strategies are recommended when ventilating a patient during a severe asthma attack.

  18. The fluid mechanics of natural ventilation

    NASA Astrophysics Data System (ADS)

    Linden, Paul

    1999-11-01

    Natural ventilation of buildings is the flow generated by temperature differences and by the wind. Modern buildings have extreme designs with large, tall open plan spaces and large cooling requirements. Natural ventilation offers a means of cooling these buildings and providing good indoor air quality. The essential feature of ventilation is an exchange between an interior space and the external ambient. Recent work shows that in many circumstances temperature variations play a controlling feature on the ventilation since the directional buoyancy force has a large influence on the flow patterns within the space and on the nature of the exchange with the outside. Two forms of buoyancy-driven ventilation are discussed: mixing ventilation in which the interior is at approximately uniform temperature and displacement ventilation where there is strong internal stratification. The dynamics of these flows are considered and the effects of wind on them are examined both experimentally and theoretically. The aim behind this work is to give designers rules and intuition on how air moves within a building and the research shows a fascinating branch of fluid mechanics.

  19. Epidemiology of Noninvasive Ventilation in Pediatric Cardiac ICUs.

    PubMed

    Romans, Ryan A; Schwartz, Steven M; Costello, John M; Chanani, Nikhil K; Prodhan, Parthak; Gazit, Avihu Z; Smith, Andrew H; Cooper, David S; Alten, Jeffrey; Mistry, Kshitij P; Zhang, Wenying; Donohue, Janet E; Gaies, Michael

    2017-10-01

    To describe the epidemiology of noninvasive ventilation therapy for patients admitted to pediatric cardiac ICUs and to assess practice variation across hospitals. Retrospective cohort study using prospectively collected clinical registry data. Pediatric Cardiac Critical Care Consortium clinical registry. Patients admitted to cardiac ICUs at PC4 hospitals. None. We analyzed all cardiac ICU encounters that included any respiratory support from October 2013 to December 2015. Noninvasive ventilation therapy included high flow nasal cannula and positive airway pressure support. We compared patient and, when relevant, perioperative characteristics of those receiving noninvasive ventilation to all others. Subgroup analysis was performed on neonates and infants undergoing major cardiovascular surgery. To examine duration of respiratory support, we created a casemix-adjustment model and calculated adjusted mean durations of total respiratory support (mechanical ventilation + noninvasive ventilation), mechanical ventilation, and noninvasive ventilation. We compared adjusted duration of support across hospitals. The cohort included 8,940 encounters from 15 hospitals: 3,950 (44%) received noninvasive ventilation and 72% were neonates and infants. Medical encounters were more likely to include noninvasive ventilation than surgical. In surgical neonates and infants, 2,032 (55%) received postoperative noninvasive ventilation. Neonates, extracardiac anomalies, single ventricle, procedure complexity, preoperative respiratory support, mechanical ventilation duration, and postoperative disease severity were associated with noninvasive ventilation therapy (p < 0.001 for all). Across hospitals, noninvasive ventilation use ranged from 32% to 65%, and adjusted mean noninvasive ventilation duration ranged from 1 to 4 days (3-d observed mean). Duration of total adjusted respiratory support was more strongly correlated with duration of mechanical ventilation compared with noninvasive

  20. Inhalation therapy in mechanical ventilation

    PubMed Central

    Maccari, Juçara Gasparetto; Teixeira, Cassiano; Gazzana, Marcelo Basso; Savi, Augusto; Dexheimer-Neto, Felippe Leopoldo; Knorst, Marli Maria

    2015-01-01

    Patients with obstructive lung disease often require ventilatory support via invasive or noninvasive mechanical ventilation, depending on the severity of the exacerbation. The use of inhaled bronchodilators can significantly reduce airway resistance, contributing to the improvement of respiratory mechanics and patient-ventilator synchrony. Although various studies have been published on this topic, little is known about the effectiveness of the bronchodilators routinely prescribed for patients on mechanical ventilation or about the deposition of those drugs throughout the lungs. The inhaled bronchodilators most commonly used in ICUs are beta adrenergic agonists and anticholinergics. Various factors might influence the effect of bronchodilators, including ventilation mode, position of the spacer in the circuit, tube size, formulation, drug dose, severity of the disease, and patient-ventilator synchrony. Knowledge of the pharmacological properties of bronchodilators and the appropriate techniques for their administration is fundamental to optimizing the treatment of these patients. PMID:26578139