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1

LLCD operations using the Lunar Lasercom OGS Terminal  

NASA Astrophysics Data System (ADS)

The paper describes the operations of ESA's Optical Ground Station (OGS) during the Lunar Laser Communications Demonstration (LLCD) experiment, performed in October and November 2013 with NASA's Lunar Atmospheric and Dust Environmental Explorer (LADEE) spacecraft. First the transmitter and receiver designs at the OGS telescope are described, which are geometrically separated to prevent cross-talk. Problems encountered and the lesson learned will be explained. As it turned the chosen arrangement was not sufficiently stable in terms of alignment and the paper will describe the solution found. A new industrial contract has been placed for improvement of the design of two solutions will be presented, which will both be tested in a follow-up laser communication campaign, scheduled for end March 2014.

Sodnik, Zoran; Smit, Hans; Sans, Marc; Zayer, Igor; Lanucara, Marco; Montilla, Iciar; Alonso, Angel

2014-03-01

2

Work-related symptoms and inflammation among sewage plant operatives.  

PubMed

Sewage operatives at five sewage treatment plants (n = 59) and controls not exposed to sewage (n = 55) were examined to determine work-related symptoms and inflammatory responses. Symptoms were elicited using a questionnaire, and spirometry was performed. Inflammatory markers were determined in blood and nasal lavage. Workplace endotoxin and hydrogen sulfide were measured and adeno- and enterovirus antibodies were evaluated in blood. Gastrointestinal and airway symptoms, joint pains, unusual tiredness, and toxic pneumonitis were more common among operatives, and the proportion of blood neutrophils was higher among operatives as compared with controls. A relationship was found between several reported symptoms and the inflammatory markers. Hydrogen sulfide levels were very low. Endotoxin levels were generally low, but high at some work sites. PMID:15070030

Thorn, Jörgen; Beijer, Lena

2004-01-01

3

Zenker's diverticulum: aetiopathogenesis, symptoms and diagnosis. Comparison of operative methods  

PubMed Central

Zenker’s diverticulum is an alimentary tract pouch localized in the area of the upper esophageal sphincter. Treatment procedure complications and coexisting diseases constitute a serious diagnostic and therapeutic problem. Characteristic symptoms and signs facilitate differential diagnosis, simultaneously being real patient maladies. There are many treatment procedures leading to pouch septum reduction and decrease of upper esophageal sphincter pressure. After years of experience in operating and endoscopic treatments we found it necessary to compare these different methods.

Nehring, Piotr

2013-01-01

4

Comparison of the symptoms reported by post-operative patients with cancer and nurses' perception of patient symptoms.  

PubMed

The purpose of this study was to compare the symptoms reported by patients with cancer after palliative surgery and mechanical ventilation in an intensive care unit (ICU) with their primary nurses' perception of the symptoms. The study adopted a descriptive and correlational study design. The sample comprised 60 Turkish patients with cancer who had been mechanically ventilated for 1-12?h at the ICU following palliative surgery. In addition to the patients' reports, the nurses (=?8) independently rated their own perceptions of the patients' symptoms. Data were collected using the Edmonton Symptom Assessment Scale (ESAS). The mean age of the sample was 62.28 years (SD = 15.02; range: 27-86). The mean score of the patients on the ESAS was 55.17 (SD = 26.16) and that of the nurses was 55.48 (SD = 27.13). The study found no statistically significant differences between scores of patients' reports and nurses' assessments of symptoms, except for the category of pain. Patients reported more pain than the nurses' perceived (Z = -2.311, P = 0.021). Systematic and frequent symptom assessments of patients in ICUs after palliative surgical operations should be an integral part of nursing care. PMID:24134532

Guner, C K; Akin, S; Durna, Z

2014-07-01

5

Luhmann og skriften  

Microsoft Academic Search

Hos Luhmann spiller skriften en vigtig rolle. Dels fordi han var ekstremt skrivende og havde sin lyst og last i ord, som kom let til ham og som endda havde farver, når han læste. Dels fordi skriften var et vigtigt led både i hans analyse af, hvordan sociale systemer stabiliserer sig, og i hans komplicerede redegørelse for, hvordan psykiske og

Ole Thyssen

2000-01-01

6

Chronic post-treatment symptoms in patients with breast cancer operated in different surgical units  

Microsoft Academic Search

AimsThis study was designed to find out whether women operated in high volume surgical units have less chronic symptoms than women operated in smaller volume units.MethodsA questionnaire was sent to 265 consecutive women treated at the Department of Oncology, Helsinki University Central Hospital, from January to June 1996. Of the patients, 129 were operated in hospitals experienced in breast cancer

T. Tasmuth; C. Blomqvist; E. Kalso

1999-01-01

7

An analysis of post-traumatic stress symptoms in United States Air Force drone operators.  

PubMed

Remotely piloted aircraft (RPA), commonly referred to as "drones," have emerged over the past decade as an innovative warfighting tool. Given there is a paucity of empirical research assessing drone operators, the purpose of this study was to assess for the prevalence of PTSD symptoms among this cohort. Of the 1084 United States Air Force (USAF) drone operators that participated, a total of 4.3% endorsed a pattern of symptoms of moderate to extreme level of severity meeting criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders-4th edition. The incidence of PTSD among USAF drone operators in this study was lower than rates of PTSD (10-18%) among military personnel returning from deployment but higher than incidence rates (less than 1%) of USAF drone operators reported in electronic medical records. Although low PTSD rates may be promising, limitations to this study are discussed. PMID:24907535

Chappelle, Wayne; Goodman, Tanya; Reardon, Laura; Thompson, William

2014-06-01

8

A cross-sectional study of the relation between symptoms and physical findings in computer operators  

PubMed Central

Background The character of upper limb disorder in computer operators is subject to debate. A peripheral nerve-involvement is suggested from the common presence of a triad of symptoms consisting of pain, paraestesiae and subjective weakness, and from physical findings suggesting neuropathy. This study aimed to examine the outcome of a detailed neurological examination in computer operators and to compare findings with the presence of symptoms. Methods 96 graphical computer operators answered a modified Nordic Questionnaire including information on perceived pain in the shoulder, elbow, and wrist/hand scored for each region on a VAS-scale 0 – 9. In addition, they underwent a physical examination including the subjective assessment of the individual function of 11 upper limb muscles, of algesia in five and vibratory threshold in three territories, respectively, and of mechanosensitivity of nerves at seven locations. In order to reflect an involvement of the brachial plexus (chord level), the posterior interosseous nerve and the median nerve at elbow level we defined three patterns of neurological findings illustrating the course of nerves and their innervation. The pain scores summarized for the three upper limb regions (min. = 0, max = 27) in the mouse-operating and contralateral limbs were compared by a Wilcoxon test and the relation to each physical item analyzed by Kendall's rank correlation. The relation of summarized pain to each pattern was studied by application of a test of the trend across ordered groups (patterns). Results Pain, paraestesiae and subjective weakness was reported for 67, 23, and 7 mouse-operating limbs, respectively, with the summarized pain scores exceeding 4 in 33 limbs. Abnormal physical findings were prevalent. The summarized pain was significantly related to a reduced function in five muscles, to mechanical allodynia at one location and to elevated threshold to vibration in two territories. Brachial plexopathy was diagnosed in 9/2, median neuropathy in 13/5 and posterior interosseous neuropathy in 13/8 mouse operating/contralateral limbs, respectively. The summarized pain was significantly higher in the mouse-operating limbs and in limbs with any of the defined patterns. There was a significant trend between the summarized pain and the summarized scores for the items contained in each pattern. Conclusion This small-scale study of a group of computer-operators currently in work and with no or minor upper limb symptoms has indicated in symptomatic subjects the presence of peripheral nerve-afflictions with specific locations.

Jepsen, J?rgen R; Thomsen, Gert

2006-01-01

9

VIDENSKAB OG PRAKSIS |SEKUNDÆRPUBLIKATION  

Microsoft Academic Search

veal karnydannelse i aktiv fase. Maculadegeneration er dog langsomt progredierende og længerevarende opfølgning af be- handlingen med pegaptanib er nødvendig for fuldstændig at karakterisere sikkerhed og behandlingseffekt. De foreliggende resultater støtter den videre udforskning af VEGF-inhibition til patienter med neovaskulær og eksudativ øjensygdom. SummaryMichael Larsen, Birgit Sander, Jørgen Villumsen, Per Haamann, Morten la Cour, Henrik Lund-Andersen & VEGF Inhibition Study

2005-01-01

10

Individual and work related factors associated with symptoms of musculoskeletal complaints. II. Different risk factors among sewing machine operators.  

PubMed Central

Individual and work related risk factors in the development of occupational musculoskeletal complaints were studied in a group of 210 female production workers, mainly sewing machine operators. Another group of 35 female employees performing secretarial or laboratory duties were also included. The production workers had significantly higher symptom scores with respect to self reported musculoskeletal complaints than the group with more varied work tasks for the head, neck, shoulders, and arms, but not for the low back, hips, and the lower extremities. No significant differences were found in symptom level between geographically separate groups of production workers with similar work tasks. The main individual risk factor identified in this study was the experience of previous, similar symptoms in the same body region, but this factor only accounted for 2-3% of total variance in symptom score for the neck and shoulders. Other individual factors of importance for symptoms in the neck and shoulders were "signs of psychological problems" and "tendency of muscle tension," but these only account for about 1% of total variance in symptom score. Symptoms in the head and low back showed complex relations with individual parameters.

Westgaard, R H; Jansen, T

1992-01-01

11

Screening for Depressive Disorders Using the Mood and Anxiety Symptoms Questionnaire Anhedonic Depression Scale: A Receiver-Operating Characteristic Analysis  

ERIC Educational Resources Information Center

The present study examined the utility of the anhedonic depression scale from the Mood and Anxiety Symptoms Questionnaire (MASQ-AD scale) as a way to screen for depressive disorders. Using receiver-operating characteristic analysis, we examined the sensitivity and specificity of the full 22-item MASQ-AD scale, as well as the 8- and 14-item…

Bredemeier, Keith; Spielberg, Jeffery M.; Silton, Rebecca Levin; Berenbaum, Howard; Heller, Wendy; Miller, Gregory A.

2010-01-01

12

Thermal Comfort, Perceived Air Quality and Intensity of SBS Symptoms During Exposure to Moderate Operative Temperature Ramps  

Microsoft Academic Search

SUMMARY The objective of the presented research work was to study the effects of moderate operative temperature drifts on human thermal comfort, perceived air quality, and intensity of SBS symptoms. Experimental subjects (52, 50% female) were seated in a climatic chamber and exposed to operative temperature ramps with different slope, direction and duration during two related experiments (±0.6 K\\/h, ±1.2

J. Kolarik; B. W. Olesen; J. Toftum; Lorenzo Mattarolo

13

Jarring\\/jolting exposure and musculoskeletal symptoms among farm equipment operators  

Microsoft Academic Search

Vehicle vibration exposure has been linked to chronic back pain and low-back symptoms among agricultural tractor drivers. The objectives of this study by the National Institute for Occupational Safety and Health (NIOSH) were to assess driver whole-body vibration (WBV) exposures and recommend interventions to reduce the risk of back-related injuries, particularly relative to vehicle jarring\\/jolting (the transient mechanical shock components

A. G. Mayton; N. K. Kittusamy; D. H. Ambrose; C. C. Jobes; M. L. Legault

2008-01-01

14

Faults, Symptoms, and Software Fault Tolerance in the Tandem GUARDIAN90 Operating System  

Microsoft Academic Search

The authors present a measurement-based study of software failures and recovery in the Tandem GUARDIAN90 operating system using a collection of memory dump analyses of field software failures. They identify the effects of software faults on the processor state and trace the propagation of the effects to other areas of the system. They also evaluate the role of the defensive

Inhwan Lee; Ravishankar K. Iyer

1993-01-01

15

What Symptom Improvement Can Be Expected After Operation for Primary Hyperparathyroidism?  

Microsoft Academic Search

Background  The only cure for primary hyperparathyroidism (pHPT) is operative resection of the parathyroid gland(s) responsible for the\\u000a disease. The 1990 National Institute of Health’s (NIH) consensus development conference on asymptomatic pHPT and its subsequent\\u000a workshop in 2001 established which clinical criteria warranted parathyroidectomy (PTx) versus observation. While there is\\u000a no debate that these NIH criteria capture a group of patients

Nadine R. Caron; Janice L. Pasieka

2009-01-01

16

Association between a quantitative measure of tactile acuity and hand symptoms reported by operators of power tools.  

PubMed

An association between a quantitative measure of tactile acuity at the fingertips and symptoms of reduced manipulative function, as established by responses to a questionnaire, was demonstrated in a population of 81 manual workers from the mining industry (62 power-tool operators and 19 nonusers). Mechanoreceptor-specific vibrotactile thresholds were determined for the slowly adapting type I (SAI) and fast-adapting types I and II (FAI and FAII) receptors at the fingertip of the third digit of each hand. Statistically significant threshold shifts in SAI and/or FAII acuity were found in persons responding affirmatively to questions concerning finger/hand numbness, blanching, and difficulty buttoning clothing. The best predictors of a quantitative change in tactile acuity were questions relating to difficulty manipulating small objects and buttoning clothing, yielding positive predictive values of from 90% to 100% and false positive rates of from 0% to 2.8%. The demonstration of an association between a quantitative measure of tactile acuity at the fingertips and some symptom reports, obtained by means of a questionnaire, provides the basis for the development of a screening procedure for persons at risk of such disturbances in hand function. PMID:9330148

Coutu-Wakulczyk, G; Brammer, A J; Piercy, J E

1997-09-01

17

Symptoms of Early Dementia-11 Questionnaire (SED-11Q): A Brief Informant-Operated Screening for Dementia  

PubMed Central

The aim of this study was to develop a brief informant-based questionnaire, namely the Symptoms of Early Dementia-11 Questionnaire (SED-11Q), for the screening of early dementia. 459 elderly individuals participated, including 39 with mild cognitive impairment in the Clinical Dementia Rating scale (CDR) 0.5, 233 with mild dementia in CDR 1, 106 with moderate dementia in CDR 2, and 81 normal controls in CDR 0. Informants were required to fill out a 13-item questionnaire. Two items were excluded after analyzing sensitivities and specificities. The final version of the SED-11Q assesses memory, daily functioning, social communication, and personality changes. Receiver operator characteristic curves assessed the utility to discriminate between CDR 0 (no dementia) and CDR 1 (mild dementia). The statistically optimal cutoff value of 2/3, which indicated a sensitivity of 0.84 and a specificity of 0.90, can be applied in the clinical setting. In the community setting, a cutoff value of 3/4, which indicated a sensitivity of 0.76 and a specificity of 0.96, is recommended to avoid false positives. The SED-11Q reliably differentiated nondemented from demented individuals when completed by an informant, and thus is practical as a rapid screening tool in general practice, as well as in the community setting, to decide whether to seek further diagnostic confirmation.

Maki, Yohko; Yamaguchi, Tomoharu; Yamaguchi, Haruyasu

2013-01-01

18

Hjemmefyldestation for naturgasdrevne biler. Installation, drift og service. (A domestic gas pump for natural-gas driven cars. Installation, operation and servicing).  

National Technical Information Service (NTIS)

A manual giving guidelines for the installation, operation and servicing of a domestic gas pump for natural-gas driven cars. The design of the gas pump in question is not yet authorized in Denmark but permission has been given to set an example up for tes...

P. Pedersen

1993-01-01

19

The predictive value of pre-operative symptoms including upper gastrointestinal endoscopy before laparoscopic cholecystectomy for elective symptomatic cholecystolithiasis.  

PubMed

Background It has always been a challenge to distinguish between upper gastrointestinal symptoms due to gall stones or any other causes. The persistence of abdominal symptoms even after cholecystectomy is highly discouraging for surgeons. Objective To evaluate the value of preoperative (UGE) as a routine investigative tool in patients with gall stone disease and to assess the outcome of cholecystectomy in patients with gallstones on preoperative abdominal symptoms. Methods This is a prospective study conducted on 96 cases at the Department of Surgery, Dhulikhel Hospital among ultrasonographically proven gall bladder stones irrespective of age and sex. After the examination, all the patients were subjected to UGE, and biopsy were obtained for histopathology if required. The statistical analysis were performed using spss version 16. Results Out of total patients, 84(87.5%) were females and 12(12.5%) were males with a M: F ratio of 1:7. Both the sexes were comparable in age groups. Out of total 96 patients, 53(55.2%) presented with typical pain and 43(44.8%) presented with atypical pain. All the patients were subjected to upper gastrointestinal endoscopy (UGE) and 53(55.2%) had normal findings and 43(44.8%) had various lesions. Patients with typical pattern of pain had normal endoscopic findings and those with atypical pain had pathology in upper gastroendoscopy (p<0.001). Serious pathology resulting to change of the planned treatment was found in three cases (3.12%). Among them two had gastric carcinoma and one had active peptic ulcer disease. The relief rate after the cholecystectomy was significant in patients with typical pain than among those with atypical pain (p<0.001). The commenest post cholecystectomy symptoms were heart burn (10%), abdominal discomfort (9%) and dyspepsia (7%). Conclusion Presence of atypical pain in patients with gall stones is highly likely to have other coexisting upper gastrointestinal pathologies. Hence, upper gastrointestinal endoscopy prior to elective cholecystectomy in patients with gall stones can be clinically helpful. PMID:24899324

Karmacharya, A; Malla, B R; Joshi, H N; Gurung, R B; Rajbhandari, M

2013-01-01

20

High prevalence of respiratory symptoms among workers in the development section of a manually operated coal mine in a developing country: A cross sectional study  

PubMed Central

Background Few studies of miners have been carried out in African countries; most are from South Africa, where the working conditions are assumed to be better than in the rest of Africa. Several studies have focused on respiratory disorders among miners, but development workers responsible for creating underground road ways have not been studied explicitly. This is the first study assessing the associations between exposure to dust and quartz and respiratory symptoms among coal mine workers in a manually operated coal mine in Tanzania, focusing on development workers, as they have the highest exposure to coal dust. Methods A cross-sectional study was carried out among 250 production workers from a coal mine. Interviews were performed using modified standardized questionnaires to elicit information on occupational history, demographics, smoking habits and acute and chronic respiratory symptoms. The relationships between current dust exposure as well as cumulative respirable dust and quartz and symptoms were studied by group comparisons as well as logistic regression. Results Workers from the development group had the highest dust exposure, with arithmetic mean of 10.3 mg/m3 for current respirable dust and 1.268 mg/m3 for quartz. Analogous exposure results for mine workers were 0.66 mg/m3 and 0.03 mg/m3, respectively; and for other development workers were 0.88 mg/m3 and 0.10 mg/m3, respectively. The workers from the development section had significantly higher prevalence of the acute symptoms of dry cough (45.7%), breathlessness (34.8%) and blocked nose (23.9%). In addition, development workers had significantly more chronic symptoms of breathlessness (17.0%) than the mine workers (6.4%) and the other production workers (2.4%). The highest decile of cumulative exposure to respirable dust was significantly associated with cough (OR = 2.91, 95% CI 1.06, 7.97) as were cumulative exposure to quartz and cough (OR = 2.87, CI 1.05, 7.88), compared with the reference consisting of the group of workers with the lowest quartile of the respective cumulative exposure. Conclusion The development workers in a coal mine had more acute and chronic respiratory symptoms than the mine and the other production workers. In addition, there was an association between high cumulative coal dust and respiratory symptoms.

Mamuya, Simon HD; Bratveit, Magne; Mashalla, Yohana; Moen, Bente E

2007-01-01

21

Symptom Management  

MedlinePLUS

... TBI Educational Materials Research DVBIC Locations Press Symptom Management A brain injury can affect a person physically ... Diagnosis and Assessment Treatment and Recovery Caregiving Symptom Management Life After TBI Defense and Veterans Brain Injury ...

22

Grunnforskning og økonomisk vekst: Ikke-instrumentell kunnskap  

Microsoft Academic Search

I denne rapporten drøfter vi grunnforskningens betydning for økonomisk vekst og velferdsutvikling. Innledningsvis drøftes hvilke deler av forskning generelt, og grunnforskning spesielt, økonomiske rasjonaler har betydning for. Instrumentalitet, i hvilken grad langsiktig forskning begrunnes og utformes etter verdier og målsettinger utenom kunnskapsinterne målsettinger står sentralt i denne drøftingen. Fordi vurderinger av instrumentalitet eller relevans er situasjonsbetinget er det begrenset hvordan

Johan Hauknes

23

Effects of a standard operating procedure on prehospital emergency care of patients presenting with symptoms of the acute coronary syndrome.  

PubMed

To determine whether a standard operating procedure (SOP) for prehospital management of patients with the acute coronary syndrome (ACS) improves the quality of patient care in terms of adherence to treatment guidelines of the European Society of Cardiology. Among a total of 1025 patient medical records collected from a period before and after the introduction of the SOP, 269 records included the working diagnosis of ACS and were then reviewed for guideline adherence. Most aspects of patient evaluation, monitoring, treatment, and hospital allocation were fairly guideline adherent (>70%) before the SOP was introduced and were not affected by the SOP. The percentage of cases in whom sublingual nitrate (55.2 vs. 66.7%) or intravenous morphine (26.9 vs. 43.0%) was administered without contraindications was higher after the SOP had been introduced. Therefore, the use of an SOP in prehospital emergency medicine can partly improve the adherence to guideline recommendations for the treatment of patients with ACS. PMID:23411814

Francis, Roland C; Bubser, Florian; Schmidbauer, Willi; Spies, Claudia D; Sörensen, Marc; Bosse, Götz; Kerner, Thoralf

2014-06-01

24

Rotavirus Symptoms  

MedlinePLUS

... message, please visit this page: About CDC.gov . Rotavirus Facebook Reccomend Twitter Tweet Share Compartir Add this ... Favorites Delicious Digg Google Bookmarks Symptoms Español: Síntomas Rotavirus disease is most common in infants and young ...

25

Syphilis Symptoms  

MedlinePLUS

... JavaScript on. Read more information on enabling JavaScript. Syphilis Skip Content Marketing Share this: Main Content Area ... occurs in four stages that sometimes overlap. Primary Syphilis The first symptom of primary syphilis is often ...

26

OGS improvements in the year 2011 in running the Northeastern Italy Seismic Network  

NASA Astrophysics Data System (ADS)

The Centro di Ricerche Sismologiche (CRS, Seismological Research Center) of the Istituto Nazionale di Oceanografia e di Geofisica Sperimentale - OGS (Italian National Institute for Oceanography and Experimental Geophysics) in Udine (Italy) after the strong earthquake of magnitude Mw = 6.4 occurred in 1976 in the Italian Friuli-Venezia Giulia region, started to operate the Northeastern Italy Seismic Network: it currently consists of 12 very sensitive broad band and 21 simpler short period seismic stations, all telemetered to and acquired in real time at the OGS-CRS data centre in Udine. Real time data exchange agreements in place with other Italian, Slovenian, Austrian and Swiss seismological institutes lead to a total number of 93 seismic stations acquired in real time, which makes the OGS the reference institute for seismic monitoring of Northeastern Italy, as shown in Fig. 1 (Bragato et al., 2011; Saraò et al., 2010). Since 2002 OGS-CRS is using the Antelope software suite as the main tool for collecting, analyzing, archiving and exchanging seismic data, initially in the framework of the EU Interreg IIIA project "Trans-national seismological networks in the South-Eastern Alps" (Bragato et al., 2010; Pesaresi et al., 2008). SeisComP is also used as a real time data exchange server tool. In order to improve the seismological monitoring of the Northeastern Italy area, at OGS-CRS we tuned existing programs and created ad hoc ones like: a customized web server named PickServer to manually relocate earthquakes, a script for automatic moment tensor determination, scripts for web publishing of earthquake parametric data, waveforms, state of health parameters and shaking maps, noise characterization by means of automatic spectra analysis, and last but not least scripts for email/SMS/fax alerting. A new OGS-CRS real time seismological website (http://rts.crs.inogs.it/) has also been operative since several years.

Bragato, P. L.; Pesaresi, D.; Saraò, A.; Di Bartolomeo, P.; Durì, G.

2013-04-01

27

Psychosocial buffers of traumatic stress, depressive symptoms, and psychosocial difficulties in veterans of Operations Enduring Freedom and Iraqi Freedom: The role of resilience, unit support, and postdeployment social support  

Microsoft Academic Search

BackgroundLittle research has examined the role of protective factors such as psychological resilience, unit support, and postdeployment social support in buffering against PTSD and depressive symptoms, and psychosocial difficulties in veterans of Operations Enduring Freedom (OEF) and Iraqi Freedom (OIF).

Robert H. Pietrzak; Douglas C. Johnson; Marc B. Goldstein; James C. Malley; Alison J. Rivers; Charles A. Morgan; Steven M. Southwick

2010-01-01

28

Menopausal Symptoms  

Microsoft Academic Search

Menopause is considered to be a major turning point in a women's life. It is accompanied by a variety of physical and psychological\\u000a changes that can significantly impair one's quality of life. Menopausal symptoms among cancer survivors often occur at an\\u000a earlier age, and can be more frequent, last longer, and be more severe than are seen in women experiencing

Debra L. Barton; Aditya Bardia; Charles Loprinzi

29

OGS improvements in the year 2011 in running the Northeastern Italy Seismic Network  

NASA Astrophysics Data System (ADS)

The Centro di Ricerche Sismologiche (CRS, Seismological Research Center) of the Istituto Nazionale di Oceanografia e di Geofisica Sperimentale (OGS, Italian National Institute for Oceanography and Experimental Geophysics) in Udine (Italy) after the strong earthquake of magnitude M=6.4 occurred in 1976 in the Italian Friuli-Venezia Giulia region, started to operate the Northeastern Italy Seismic Network: it currently consists of 15 very sensitive broad band and 21 simpler short period seismic stations, all telemetered to and acquired in real time at the OGS-CRS data center in Udine. Real time data exchange agreements in place with other Italian, Slovenian, Austrian and Swiss seismological institutes lead to a total number of about 100 seismic stations acquired in real time, which makes the OGS the reference institute for seismic monitoring of Northeastern Italy. Since 2002 OGS-CRS is using the Antelope software suite on several workstations plus a SUN Cluster as the main tool for collecting, analyzing, archiving and exchanging seismic data, initially in the framework of the EU Interreg IIIA project "Trans-national seismological networks in the South-Eastern Alps". SeisComP is also used as a real time data exchange server tool. In order to improve the seismological monitoring of the Northeastern Italy area, at OGS-CRS we tuned existing programs and created ad hoc ones like: a customized web server named PickServer to manually relocate earthquakes, a script for automatic moment tensor determination, scripts for web publishing of earthquake parametric data, waveforms, state of health parameters and shaking maps, noise characterization by means of automatic spectra analysis, and last but not least scripts for email/SMS/fax alerting. The OGS-CRS Real Time Seismological website (RTS, http://rts.crs.inogs.it/) operative since several years was initially developed in the framework of the Italian DPC-INGV S3 Project: the RTS website shows classic earthquake locations parametric data plus ShakeMap and moment tensor information. At OGS-CRS we also spent a considerable amount of efforts in improving the long-period performances of broadband seismic stations, either by carrying out full re-installations and/or applying thermal insulations to the seismometers: more examples of PSD plots of the PRED broad band seismic station installation in the cave tunnel of Cave del Predil using a Quanterra Q330HR high resolution digitizer and a Sterckeisen STS-2 broadband seismometer will be illustrated. Efforts in strengthening the reliability of data links, exploring the use of redundant satellite/radio/GPRS links will also be shown.

Bragato, P. L.; Pesaresi, D.; Saraò, A.; Di Bartolomeo, P.; Dur?, G.

2012-04-01

30

Petroleumsvirksomhet i isfylte farvann - utbyggings- og driftsfase. Maalfokusering for eventuell konsekvensutredning. Arbeidsdokument fra AKU/AEAM-seminar, Stavanger 4. - 6. desember 1995. (Petroleum activity in ice covered waters - development and operation phase. Focus of eventual consequential explanation).  

National Technical Information Service (NTIS)

This report from a seminar relates to the petroleum activities in the Barentshavet north. The focal point was to put on petroleum activities in ice covered waters covering the drilling and operation phase, to identify discharges from various technical sol...

J. Thomassen K. H. Andresen K. A. Moe

1996-01-01

31

Acquiring, archiving, analyzing and exchanging seismic data in real time at the Seismological Research Center of the OGS in Italy  

NASA Astrophysics Data System (ADS)

The Centro di Ricerche Sismologiche (CRS, Seismological Research Center) of the Istituto Nazionale di Oceanografia e di Geofisica Sperimentale (OGS, Italian National Institute for Oceanography and Experimental Geophysics) in Udine (Italy) after the strong earthquake (magnitude M=6.4) occurred in 1976 in the Italian Friuli-Venezia Giulia region, started to operate the North-east Italy (NI) seismic network: it currently consists of 11 very sensitive broad band and 23 more simple short period seismic stations, all telemetered to and acquired in real time at the OGS-CRS data center in Udine. Real time data exchange agreements in place with other Italian, Slovenian, Austrian and Swiss seismological institutes lead to a total number of 89 seismic stations acquired in real time, which makes the OGS the reference institute for seismic monitoring of Northeastern Italy. Since 2002 OGS-CRS is using the Antelope software suite as the main tool for collecting, analyzing, archiving and exchanging seismic data in the framework of the EU Interreg IIIA project "Trans-national seismological networks in the South-Eastern Alps". SeisComP is also used as a real time data exchange server tool. At OGS-CRS we then adapted existing programs and created new ones like: a customized web-accessible server to manually relocate earthquakes, a script for automatic moment tensor determination, scripts for web publishing of earthquake parametric data, waveforms, state of health parameters and shaking maps, noise characterization by means of automatic spectra analysis, plus scripts for email/SMS/fax alerting. A new OGS-CRS real time web site has also been recently designed and made operative in the framework of the DPC-INGV S3 Project.

Saraò, Angela; Pesaresi, Damiano; Bragato, Pier Luigi; di Bartolomeo, Paolo; Percy Plasencia Linares, Milton

2010-05-01

32

Symptoms of Pneumocystis pneumonia  

MedlinePLUS

... Favorites Delicious Digg Google Bookmarks Symptoms of Pneumocystis pneumonia The symptoms of PCP are fever, dry cough, ... Diagnosis & Testing Treatment & Outcomes Statistics Additional Information Pneumocystis pneumonia Definition Symptoms People at Risk & Prevention Sources Diagnosis & ...

33

Psychological Well-Being and Physical Health Symptoms of Soldiers Deployed for Operation Uphold Democracy. A Summary of Human Dimensions Research in Haiti.  

National Technical Information Service (NTIS)

A Human Dimensions Research (HDR) team was formed and sent to Haiti to assess the psychological status and adaptation of the U.S. Army force deployed for Operation Uphold Democracy. Research questionnaires were collected from 3,205 soldiers, interviews we...

R. R. Halverson P. Bliese R. E. Moore C. A. Castro

1995-01-01

34

Schizophrenia: The Characteristic Symptoms  

Microsoft Academic Search

The specific symptoms that have been felt to characterize schizophrenia have varied widely over time and across cultures, as has the diagnostic and prognostic importance placed on these symptoms. In this report, the historical concepts of what constitutes the \\

Nancy C. Andreasen; Michael Flaum

1991-01-01

35

Symptoms and Diagnosis  

MedlinePLUS

Symptoms and Diagnosis If you are new to dystonia, it can be a challenging disorder to understand. ... as primary, secondary, or dystonia-plus . ? If the dystonia occurs with symptoms of additional neurological disorders. Dystonia ...

36

Initial Symptoms of ALS  

MedlinePLUS

... Symptoms can begin in the muscles of speech, swallowing or in the hands, arms, legs or feet. Not all people with ALS experience the same symptoms or the same sequences or patterns of progression. But, progressive muscle weakness and paralysis ...

37

Pertussis Signs & Symptoms  

MedlinePLUS

... Disclaimer policy. Print page View page in Español (Spanish) Contact Us: Centers for Disease Control and Prevention ... Pertussis Homepage About Pertussis Causes & Transmission Causes & Transmission-Spanish Signs & Symptoms Symptoms-Spanish Complications Complications-Spanish Diagnosis & ...

38

Symptoms, Diagnosis & Treatment  

MedlinePLUS

... grow into (and restore) the body's blood cells. Hodgkin's Lymphoma Symptoms Painless, swollen lymph nodes in the ... leukemia" or "lymphoma" in the search box) Non-Hodgkin's Lymphoma Symptoms Swollen, painless lymph nodes in the ...

39

Hepatitis B Symptoms  

MedlinePLUS

... JavaScript on. Read more information on enabling JavaScript. Hepatitis B Skip Content Marketing Share this: Main Content Area Symptoms Hepatitis B does not always cause obvious symptoms. Children are ...

40

Psoriasis: Signs and Symptoms  

MedlinePLUS

... Diseases and treatments M - P Psoriasis Signs, symptoms Psoriasis: Signs and symptoms What you see and feel ... listed below, or you may have many. Plaque psoriasis (also called psoriasis vulgaris) Raised, reddish patches on ...

41

What is called symptom?  

PubMed

There is one concept in medicine which is prominent, the symptom. The omnipresence of the symptom seems, however, not to be reflected by an equally prominent curiosity aimed at investigating this concept as a phenomenon. In classic, traditional or conventional medical diagnostics and treatment, the lack of distinction with respect to the symptom represents a minor problem. Faced with enigmatic conditions and their accompanying labels such as chronic fatigue syndrome, fibromyalgia, medically unexplained symptoms, and functional somatic syndromes, the contestation of the symptom and its origin is immediate and obvious and calls for further exploration. Based on a description of the diagnostic framework encompassing medically unexplained conditions and a brief introduction to how such symptoms are managed both within and outside of the medical clinic, we argue on one hand how unexplained conditions invite us to reconsider and re-think the concept we call a "symptom" and on the other hand how the concept "symptom" is no longer an adequate and necessary fulcrum and must be enriched by socio-cultural, phenomenological and existential dimensions. Consequently, our main aim is to expand both our interpretative horizon and the linguistic repertoire in the face of those appearances we label medically unexplained symptoms. PMID:23877313

Eriksen, Thor Eirik; Risør, Mette Bech

2014-02-01

42

E. coli Symptoms  

MedlinePLUS

... Events NIAID > Health & Research Topics > E. coli > Understanding E. coli Understanding Overview Cause Transmission Symptoms Diagnosis Treatment Prevention Complications Research Skip Website Tools Website Tools Print ...

43

Symptoms of Celiac Disease  

MedlinePLUS

... symptoms tend to appear in children and adults? Children tend to have the more classic signs of celiac disease, including growth problems (failure to thrive, chronic diarrhea/constipation, recurring abdominal bloating and pain, fatigue and irritability. Adults tend to have symptoms ...

44

Tibolone and climacteric symptoms.  

PubMed

Tibolone (Livial) has advantages over other forms of hormone replacement therapy (HRT); it is easy to use and does not induce withdrawal bleeding in postmenopausal women. The evidence for the effect of tibolone on climacteric symptoms is reviewed and shows that tibolone is effective in reducing vasomotor symptoms and vaginal dryness. Tibolone's effect on a range of other symptoms such as headache and insomnia is unclear. There are reports that tibolone improves mood and libido but much of this research is methodologically flawed. Methodologically sound research is required to investigate tibolone's effect on mood and libido; such a study is in progress. PMID:7752950

Ross, L A; Alder, E M

1995-02-01

45

Dissociative symptoms and epilepsy.  

PubMed

This article considers the relationship between various types of dissociative symptoms, including symptoms of depersonalization, derealization, and conversion disorders, and epilepsy. After introductory remarks concerning dissociation, this relationship is discussed through two main themes: firstly, the phenomenology and mechanisms of so-called 'dreamy states' in epilepsy and their closest analogs in psychiatric disorders, and secondly, the similarities and differences between epileptic seizures and psychogenic nonepileptic attacks. Although epileptic and dissociative symptoms may appear similar to observers, they arise through different mechanisms and have different experiential qualities. PMID:24196397

Medford, Nick

2014-01-01

46

International Space Station United States Orbital Segment Oxygen Generation System On-Orbit Operational Experience  

NASA Technical Reports Server (NTRS)

The International Space Station (ISS) United States Orbital Segment (USOS) Oxygen Generation System (OGS) was originally intended to be installed in ISS Node 3. The OGS rack delivery was accelerated, and it was launched to ISS in July of 2006 and installed in the US Laboratory Module. Various modification kits were installed to provide its interfaces, and the OGS was first activated in July of 2007 for 15 hours, In October of 2007 it was again activated for 76 hours with varied production rates and day/night cycling. Operational time in each instance was limited by the quantity of feedwater in a Payload Water Reservoir (PWR) bag. Feedwater will be provided by PWR bag until the USOS Water Recovery System (WRS) is delivered to SS in fall of 2008. This paper will discuss operating experience and characteristics of the OGS, as well as operational issues and their resolution.

Erickson, Robert J.; Howe, John, Jr.; Kulp, Galen W.; VanKeuren, Steven P.

2008-01-01

47

Signs and Symptoms  

MedlinePLUS

... tachypnea) when lying down or with exertion, poor appetite and slow weight gain. Older children may show ... symptoms are difficulty breathing, excessive sweating (diaphoresis), poor appetite and failure to thrive. Older children with obstructive ...

48

Module 3 – Symptoms  

Cancer.gov

Module three of the EPEC-O (Education in Palliative and End-of-Life Care for Oncology) Self-Study Original Version presents approaches to and management of commonly encountered symptoms and syndromes of cancer patients.

49

Insect Sting Allergy: Symptoms  

MedlinePLUS

... Director, Health Initiatives View full profile Insect Sting Allergy: Symptoms Insect sting reactions can be classified as ... Calendar Read the News View Daily Pollen Count Allergy Treatment Programs At National Jewish Health, some of ...

50

Symptoms of Tickborne Illness  

MedlinePLUS

... symptoms include headache, fatigue, and muscle aches. With Lyme disease you may also experience joint pain. The severity ... disease and the patient's personal tolerance level. Rash: Lyme disease , southern tick-associated rash illness (STARI) , Rocky Mountain ...

51

Amblyopia: Lazy Eye Symptoms  

MedlinePLUS

... Reduced Vision Tearing See all Symptoms > Glasses, Contacts & LASIK Contact Lenses Colored Contact Lenses Eyeglasses IOLs Refractive Surgery & LASIK Sunglasses Living EyeSmart About Ophthalmologists Adults Under 40 ...

52

Bell's Palsy Symptoms  

MedlinePLUS

... Reduced Vision Tearing See all Symptoms > Glasses, Contacts & LASIK Contact Lenses Colored Contact Lenses Eyeglasses IOLs Refractive Surgery & LASIK Sunglasses Living EyeSmart About Ophthalmologists Adults Under 40 ...

53

Managing Concussion Symptoms  

MedlinePLUS Videos and Cool Tools

... Symptoms HealthDay May 12, 2014 Related MedlinePlus Pages Children's Health Concussion Transcript Concussions can pack a long-lasting ... head injury. The findings published in the journal Pediatrics are based on the experiences of 235 concussion ...

54

Rosacea: Signs and Symptoms  

MedlinePLUS

... treatment. Subtype 1: Facial redness, flushing, visible blood vessels Signs and symptoms Flushing and redness in the center of the face. Visible broken blood vessels (spider veins). Swollen skin. Skin may be very ...

55

Symptoms of Uterine Cancer  

MedlinePLUS

... Announcements Radio Public Service Announcements Print Materials Campaign Research Doctors Who Use Social Media Poster Presentation Buttons and Badges Related Resources Gynecologic Cancer Symptoms Diary [PDF-503KB] Uterine Cancer fact sheet [PDF-622KB] ...

56

[Neurological symptoms in poisoning].  

PubMed

Acute and chronic intoxications become manifest in primary neurological symptoms. After a definition of poisoning the autonomic, neurological and psychological disturbances are briefly discussed and the therapeutic measures presented in a table. Later, the neurological symptoms are described with reference to oberservations of cases of lead, thallium, E 605 (parathion), carbon monoxide, mercury, amphetamine and botulin poisoning. Four table and 9 figures supplement the text. PMID:6775212

Neu, I

1980-10-01

57

Contact Dermatitis: Signs and Symptoms  

MedlinePLUS

... treatments A - D Contact dermatitis Signs and symptoms Contact dermatitis: Signs and symptoms Allergic contact dermatitis : Testing ... these symptoms, you need immediate medical care. Allergic contact dermatitis This skin condition occurs when you have ...

58

Symptom assessment in cancer patients  

Microsoft Academic Search

Patients with cancer suffer from a multitude of symptoms. Effective treatment strategies are available for a number of the\\u000a common symptoms. A major reason for inadequate symptom relief is lack of effective symptom assessment. Accurate assessment\\u000a of symptoms is necessary before any treatment can be undertaken. Although there are many complexities involved in the assessment\\u000a of symptoms, simple, effective tools

Michael Naughton; Jade Homsi

2002-01-01

59

Three Years of on Orbit ISS Oxygen Generation System Operation 2007-2010  

NASA Technical Reports Server (NTRS)

The International Space Station (ISS) United States Orbital Segment (USOS) Oxygen Generation System (OGS) has accumulated 240 days of continuous operation at varied oxygen production rates within the US Laboratory Module (LAB) since it was first activated in July 2007. OGS relocated from the ISS LAB to Node 3 during 20A Flight (February 2010). The OGS rack delivery was accelerated for on-orbit checkout in the LAB, and it was launched to ISS in July of 2006. During the on-orbit checkout interval within the LAB from July 2007 to October 2008, OGS operational times were limited by the quantity of feedwater in a Payload Water Reservoir (PWR) bag. Longer runtimes are now achievable due to the continuous feedwater availability after ULF2 delivery and activation of the USOS Water Recovery System (WRS) racks. OGS is considered a critical function to maintaining six crew capability. There have been a number of failures which interrupted or threatened to interrupt oxygen production. Filters in the recirculation loop have clogged and have been replaced, Hydrogen sensors have fallen out of specifications, a pump delta pressure sensor failed, a pump failed to start, and the voltage on the cell stack increased out of tolerance. This paper will discuss the operating experience and characteristics of the OGS, as well as operational issues and their resolution.

Diderich, Greg S.; Polis, Pete; VanKeuren, Steven P.; Erickson, Bob

2010-01-01

60

Symptoms of Ovarian Cancer  

MedlinePLUS

... Announcements Radio Public Service Announcements Print Materials Campaign Research Doctors Who Use Social Media Poster Presentation Buttons and Badges Related Resources Surveying a woman’s risk podcast Gynecologic Cancer Symptoms Diary [PDF-503KB] Ovarian Cancer fact sheet [PDF-859KB] ...

61

ADHD Symptoms and Subtypes: Relationship between Childhood and Adolescent Symptoms  

ERIC Educational Resources Information Center

A study aims to examine attention-deficit/hyperactivity disorder(ADHD) symptoms and subtypes in childhood and adolescence. The results conclude the persistence of ADHD from childhood to adolescence with specific symptoms contributing to persistent ADHD.

Hurtig, Tuula; Ebeling, Hanna; Taanila, Anja; Miettunen, Jouko; Smalley, Susan L.; McGough, James J.; Loo, Sandra K.; Jarvelin, Marjo-Riitta; Moilanen, Irma K.

2007-01-01

62

Effects of thioredoxin: SUMO and intein on soluble fusion expression of an antimicrobial peptide OG2 in Escherichia coli.  

PubMed

OG2 is a modified antimicrobial peptide of Palustrin-OG1 (OG1), which is derived from Odorrana grahami frog. OG2 has shown much higher selective antimicrobial activity and lower hemolytic activity than OG1, indicating OG2 may be a promising antimicrobial agent. In this study, we investigated three fusion partners, including thioredoxin, Mxe GyrA intein, and small ubiquitin-like modifier (SUMO), each fused with OG2, and examined their effects on the expression level and solubility of OG2 in Escherichia coli. The codon-optimized OG2 gene was cloned into pET32a (+) and pTWIN1 for fusion with thioredoxin and Mxe GyrA intein, respectively. In addition, the SUMO-OG2 gene was amplified by splice overlap extension PCR method and was cloned into pET30a (+). All recombinant plasmids were then transformed into E. coli BL21(DE3)pLysS, and the expressed fusion proteins were verified. Upon isopropyl ?-D-1-thiogalactopyranoside (IPTG) induction, OG2 fused with thioredoxin (Trx-OG2) showed the highest yield as a soluble fusion protein (50 mg/L), followed by Mxe GyrA intein (44 mg/L) and SUMO (11 mg/L). The thioredoxin-fused protein (Trx-OG2) was then purified by nickel-nitrilotriacetic acid chromatography and desalted by Sephadex G25. The OG2 released by both tobacco etch virus protease and enterokinase from Trx-OG2 showed strong antimicrobial activity against Staphylococcus aureus ATCC25923. PMID:22670762

Xie, Yong-Gang; Luan, Chao; Zhang, Hai-Wen; Han, Fei-Fei; Feng, Jie; Choi, Young-Jun; Groleau, Denis; Wang, Yi-Zhen

2013-01-01

63

Large scale variation in Enterococcus faecalis illustrated by the genome analysis of strain OG1RF  

PubMed Central

Background Enterococcus faecalis has emerged as a major hospital pathogen. To explore its diversity, we sequenced E. faecalis strain OG1RF, which is commonly used for molecular manipulation and virulence studies. Results The 2,739,625 base pair chromosome of OG1RF was found to contain approximately 232 kilobases unique to this strain compared to V583, the only publicly available sequenced strain. Almost no mobile genetic elements were found in OG1RF. The 64 areas of divergence were classified into three categories. First, OG1RF carries 39 unique regions, including 2 CRISPR loci and a new WxL locus. Second, we found nine replacements where a sequence specific to V583 was substituted by a sequence specific to OG1RF. For example, the iol operon of OG1RF replaces a possible prophage and the vanB transposon in V583. Finally, we found 16 regions that were present in V583 but missing from OG1RF, including the proposed pathogenicity island, several probable prophages, and the cpsCDEFGHIJK capsular polysaccharide operon. OG1RF was more rapidly but less frequently lethal than V583 in the mouse peritonitis model and considerably outcompeted V583 in a murine model of urinary tract infections. Conclusion E. faecalis OG1RF carries a number of unique loci compared to V583, but the almost complete lack of mobile genetic elements demonstrates that this is not a defining feature of the species. Additionally, OG1RF's effects in experimental models suggest that mediators of virulence may be diverse between different E. faecalis strains and that virulence is not dependent on the presence of mobile genetic elements.

Bourgogne, Agathe; Garsin, Danielle A; Qin, Xiang; Singh, Kavindra V; Sillanpaa, Jouko; Yerrapragada, Shailaja; Ding, Yan; Dugan-Rocha, Shannon; Buhay, Christian; Shen, Hua; Chen, Guan; Williams, Gabrielle; Muzny, Donna; Maadani, Arash; Fox, Kristina A; Gioia, Jason; Chen, Lei; Shang, Yue; Arias, Cesar A; Nallapareddy, Sreedhar R; Zhao, Meng; Prakash, Vittal P; Chowdhury, Shahreen; Jiang, Huaiyang; Gibbs, Richard A; Murray, Barbara E; Highlander, Sarah K; Weinstock, George M

2008-01-01

64

Alopecia Areata: Signs and Symptoms  

MedlinePLUS

... and treatments A - D Alopecia areata Signs, symptoms Alopecia areata: Signs and symptoms If you have alopecia areata, ... dents, white spots, and roughtness. Learn more about alopecia areata: Alopecia areata Alopecia areata: Who gets and causes ...

65

Skin Cancer: Signs and Symptoms  

MedlinePLUS

... and treatments Q - T Skin cancer Signs, symptoms Skin cancer: Signs and symptoms The most common warning sign ... melanoma appears in many ways. Learn more about skin cancer: Skin cancer Skin cancer: Who gets and causes ...

66

Atopic Dermatitis: Signs and Symptoms  

MedlinePLUS

... symptoms Atopic dermatitis: Signs and symptoms Atopic dermatitis (AD) looks different in infants, children, and adults. The ... what you feel) for each age group. Infants AD can begin early. A child may be 2 ...

67

Operational Group Sandy technical progress report  

USGS Publications Warehouse

Hurricane Sandy made US landfall near Atlantic City, NJ on 29 October 2012, causing 72 direct deaths, displacing thousands of individuals from damaged or destroyed dwellings, and leaving over 8.5 million homes without power across the northeast and mid-Atlantic. To coordinate federal rebuilding activities in the affected region, the President established the cabinet-level Hurricane Sandy Rebuilding Task Force (Task Force). The Task Force was charged with identifying opportunities for achieving rebuilding success while supporting economic vitality, improving public health and safety, protecting and enhancing natural and manmade infrastructure, bolstering resilience, and ensuring appropriate accountability. The Department of the Interior (DOI) Strategic Sciences Group (SSG) was established in 2012 to provide interdisciplinary science-based scenarios for environmental crises affecting Departmental resources. In January 2013, the Secretary of the Interior directed the SSG to support the Department’s participation in the Task Force. The SSG assembled a team of experts from government, academia, and non-governmental organizations – Operational Group Sandy (OGS) – to develop scenarios for the impacts of Hurricane Sandy and future major storms on coastal communities and urban systems in the New York/New Jersey region. This report documents results from the March 2013 deployment of the OGS. It includes background information on Hurricane Sandy and the federal response; the OGS methodology; scenarios for Hurricane Sandy’s impact on coastal communities and urban ecosystems; potential interventions to improve regional resilience to future major storms; a discussion of scenario results; and lessons learned about the OGS process.

Department of the Interior Strategic Science Group

2013-01-01

68

Symptom Clusters among Young Adolescents.  

ERIC Educational Resources Information Center

Examines recurrent psychosomatic symptoms and symptom clusters among Israeli school children (n=259). Results of a questionnaire that asked about the frequency of 8 psychosomatic and 8 organic complaints indicated that girls had a higher prevalence than boys for 8 of the symptoms, and that abdominal pain and headache were each reported as an…

Knishkowsky, Barry; And Others

1995-01-01

69

Menopausal symptoms: is spirituality associated with the severity of symptoms?  

PubMed

The aim of this study was to explore whether spirituality was associated with menopausal symptoms. Menopausal symptoms, spirituality, health and menopausal status, and socio-demographic variables were assessed in a community sample of 710 peri- and postmenopausal women. A structural model was explored using structural equation modeling. The results evidence spirituality as a significant contributor regarding the severity of most menopausal symptoms. Among others, spirituality had a significant weight in depressive mood (? = -.414; p < .001), anxiety (? = -.308; p < .001), cognitive impairment (? = -.287; p < .001), aches/pain (? = -.148; p < .001), vasomotor (? = -.125; p = .005) and sexual symptoms (? = -.211; p < .001). Some socio-demographic variables, as well as perceived health, also predicted the menopausal symptoms' severity. Therefore, spirituality can have a positive impact on the menopausal symptoms' reporting. PMID:23471772

Pimenta, Filipa; Maroco, João; Ramos, Catarina; Leal, Isabel

2014-08-01

70

High-yield soluble expression and simple purification of the antimicrobial peptide OG2 using the intein system in Escherichia coli.  

PubMed

OG2 is a modified antimicrobial peptide, that is, derived from the frog peptide Palustrin-OG1. It has high antimicrobial activity and low cytotoxicity, and it is therefore promising as a therapeutic agent. Both prokaryotic (Escherichia coli) and eukaryotic (Pichia pastoris) production host systems were used to produce OG2 in our previous study; however, it was difficult to achieve high expression yields and efficient purification. In this study, we achieved high-yield OG2 expression using the intein fusion system. The optimized OG2 gene was cloned into the pTWIN1 vector to generate pTWIN-OG2-intein2 (C-terminal fusion vector) and pTWIN-intein1-OG2 (N-terminal fusion vector). Nearly 70% of the expressed OG2-intein2 was soluble after the IPTG concentration and induction temperature were decreased, whereas only 42% of the expressed of intein1-OG2 was soluble. Up to 75 mg of OG2-intein2 was obtained from a 1l culture, and 85% of the protein was cleaved by 100 mM DTT. Intein1-OG2 was less amenable to cleavage due to the inhibition of cleavage by the N-terminal amino acid of OG2. The purified OG2 exhibited strong antimicrobial activity against E. coli K88. The intein system is the best currently available system for the cost-effective production of OG2. PMID:23936842

Xie, Yong-Gang; Han, Fei-Fei; Luan, Chao; Zhang, Hai-Wen; Feng, Jie; Choi, Young-Jun; Groleau, Denis; Wang, Yi-Zhen

2013-01-01

71

High-Yield Soluble Expression and Simple Purification of the Antimicrobial Peptide OG2 Using the Intein System in Escherichia coli  

PubMed Central

OG2 is a modified antimicrobial peptide, that is, derived from the frog peptide Palustrin-OG1. It has high antimicrobial activity and low cytotoxicity, and it is therefore promising as a therapeutic agent. Both prokaryotic (Escherichia coli) and eukaryotic (Pichia pastoris) production host systems were used to produce OG2 in our previous study; however, it was difficult to achieve high expression yields and efficient purification. In this study, we achieved high-yield OG2 expression using the intein fusion system. The optimized OG2 gene was cloned into the pTWIN1 vector to generate pTWIN-OG2-intein2 (C-terminal fusion vector) and pTWIN-intein1-OG2 (N-terminal fusion vector). Nearly 70% of the expressed OG2-intein2 was soluble after the IPTG concentration and induction temperature were decreased, whereas only 42% of the expressed of intein1-OG2 was soluble. Up to 75?mg of OG2-intein2 was obtained from a 1?l culture, and 85% of the protein was cleaved by 100?mM DTT. Intein1-OG2 was less amenable to cleavage due to the inhibition of cleavage by the N-terminal amino acid of OG2. The purified OG2 exhibited strong antimicrobial activity against E. coli K88. The intein system is the best currently available system for the cost-effective production of OG2.

Xie, Yong-Gang; Han, Fei-Fei; Luan, Chao; Zhang, Hai-Wen; Feng, Jie; Choi, Young-Jun; Groleau, Denis; Wang, Yi-Zhen

2013-01-01

72

Effect of Disruption of a Gene Encoding an Autolysin of Enterococcus faecalis OG1RF  

PubMed Central

A mutant (TX5127) of Enterococcus faecalis OG1RF was generated by disruption mutagenesis of a previously described autolysin gene. TX5127 formed longer chains (2 to 10 cells per chain) than wild-type OG1RF (mainly single cells) during growth in broth even though it had a growth rate similar to that of the parental strain as measured by turbidity and cell count. Autolysin activity, as defined by the ability to lyse heat-killed Micrococcus lysodeikticus cells, was absent in TX5127, while this activity was easily detectable in OG1RF. However, disruption of this autolysin gene did not block the ability of TX5127 to hydrolyze E. faecalis cell walls compared to that of OG1RF. The autolysis rate of cells of TX5127 in 10 mM sodium phosphate buffer (pH 6.8) was slower than that of wild-type OG1RF. TX5127 also showed a decreased rate of lysis in the presence of penicillin, as measured by changes in the turbidity of the culture during 24 h of incubation at 37°C and a slightly decreased effect of penicillin as measured by time-kill curves. The virulence of TX5127 was similar to that of OG1RF in the mouse peritonitis model, indicating that the autolysin of E. faecalis is not important for infection in this model.

Qin, Xiang; Singh, Kavindra V.; Xu, Yi; Weinstock, George M.; Murray, Barbara E.

1998-01-01

73

Remedies for Common Cold Symptoms  

PubMed Central

Individuals suffering from intolerable symptoms of the common cold can now be advised of safe and effective products for symptomatic relief. This article describes and discusses four categories of drugs used to treat the common cold. To simplify the product selection process for family physicians, suggestions are included for possible ingredients for treatments of specific cold symptoms.

Miller, Penny F.

1991-01-01

74

Symptom attribution in cultural perspective.  

PubMed

The explanatory model perspective of medical anthropology emphasizes the cultural shaping of individuals' efforts to make sense of their symptoms and suffering. Causal attribution is a pivotal cognitive process in this personal and social construction of meaning. Cultural variations in symptom attribution affect the pathogenesis, course, clinical presentation and outcome of psychiatric disorders. Research suggests that styles of attribution for common somatic symptoms may influence patients' tendency to somatize or psychologize psychiatric disorders in primary care. At the same time, symptom attributions are used to negotiate the sociomoral implications of illness. Recent work in social psychology and medical anthropology emphasizes the roots of attributional processes in bodily and social processes that are highly context-dependent, and hence, must be understood as part of the construction of a local world of meaning. Symptom attributions then may be understood as forms of positioning with both cognitive and social consequences relevant to psychiatric assessment and intervention. PMID:7828110

Kirmayer, L J; Young, A; Robbins, J M

1994-12-01

75

A Socio-Technical Perspective on Integrated Operations for High-Risk and Complex Industrial Assets: Experience from North Sea Oil & Gas Industry  

Microsoft Academic Search

During 2003 it became very obvious that oil and gas (O&G) exploration and production activities on North Sea was at a crossroad.\\u000a Norwegian O&G industry during 2003–2004 made a strategic decision to step into a major re-engineering process of offshore\\u000a activities. Subsequently the concept of ‘Integrated eOperations’ was born and is currently under a rapid implementation path.\\u000a So far, the

Jayantha P. Liyanage

76

Impact of ADHD symptoms on autism spectrum disorder symptom severity.  

PubMed

Despite the official exclusion criteria for autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) in the DSM-IV and ICD-10, patients with ASD often show ADHD symptoms. We aimed to examine the potential influence of ADHD symptoms on autistic psychopathology in a large sample of patients with ASD. We tested the hypothesis that patients with ASD and an additional ADHD (ASD+) would show a higher severity of autistic symptoms than those with ASD only (ASD-). We measured autistic symptoms using the autism diagnostic observation schedule (ADOS-G), the autism diagnostic interview (ADI-R), and the social responsiveness scale (SRS). To measure overall psychopathology and ADHD symptoms, we used the child behavior checklist (CBCL) and the ADHD rating scale (FBB-ADHS), respectively. Group differences between the ASD+ and the ASD- group (group division was conducted according to the results of the FBB-ADHS) were calculated using a univariate analysis of variance (ANOVA). The ASD+ group showed a greater severity of autistic symptoms than the ASD- group, measured by the SRS and the ADI-R. Especially in the social interaction subscale (ADI-R), a significantly higher symptom severity was found in the ASD+ group. No significant group differences were found regarding autistic symptoms measured by the ADOS-G. Patients with ASD and an additional ADHD expressed a stronger severity of autistic symptoms than patients with ASD only. According to our results, the possibility of a co-diagnosis of ADS and ADHD, as is being planned in the DSM-5, is in line with earlier studies, is highly reasonable, will simplify research, and have therapeutic implications. PMID:23973801

Sprenger, Linda; Bühler, Eva; Poustka, Luise; Bach, Christiane; Heinzel-Gutenbrunner, Monika; Kamp-Becker, Inge; Bachmann, Christian

2013-10-01

77

Neuropsychological symptoms and occupational exposure to anaesthetics.  

PubMed Central

OBJECTIVE--To analyse the relation between symptoms regularly reported by hospital personnel and exposure to anaesthetics. SETTING--Personnel of 18 hospitals in Paris from 1987 to 1989. DESIGN--An exposed group that included all operating theatre members except for doctors, and which was divided into three subgroups depending on the degree of exposure--exposure was measured by the frequency of the use of the scavenging system--and a control group that included other hospital personnel matched by hospital, sex, occupation, age, and duration of service. SUBJECTS--557 exposed workers and 566 unexposed workers. MAIN OUTCOME MEASURES--The groups were compared according to the crude rates of regular symptoms. Adjusted odds ratios were calculated to estimate the risks associated with exposure to anaesthetic gas. Liver transaminase activities (alanine aminotransferase, aspartate aminotransferase (s-ASAT, and gamma-glutamyl transpeptidase) were measured and compared between groups of exposure. RESULTS--After controlling for working conditions and matching factors, neuropsychological symptoms and tiredness were reported more by workers in less often scavenged theatres than by controls. No difference was found between workers of the well scavenged theatres and controls. Among the exposed workers, the members of paediatric surgical staffs reported a higher rate of neurological complaints (tingling, numbness, cramps) and tiredness than the members of the other surgical staffs. They had a high value of s-ASAT more frequently than the other exposed workers. CONCLUSION--These results strengthen the hypothesis of a causal relation between exposure to anaesthetics and neuropsychological symptoms, and show a dose-response effect. They suggest that the use of ventilating systems in operating rooms is an effective means of prevention.

Saurel-Cubizolles, M J; Estryn-Behar, M; Maillard, M F; Mugnier, N; Masson, A; Monod, G

1992-01-01

78

TBI Symptoms, Diagnosis, Treatment, Prevention  

MedlinePLUS

... Home Current Issue Past Issues Cover Story: Traumatic Brain Injury TBI Symptoms, Diagnosis, Treatment, Prevention Past Issues / Fall ... lucky in my ongoing recovery from the traumatic brain injury I suffered in Iraq." —Bob Woodruff Treatment Immediate ...

79

Menopause: Symptom Relief and Treatments  

MedlinePLUS

... symptom, your mood swings may get better too. Memory problems Some women complain of memory problems or trouble focusing in midlife. But studies ... Women should not use MHT to protect against memory loss or brain diseases, including dementia and Alzheimer's ...

80

Paroxysmal symptoms in multiple sclerosis.  

PubMed Central

The clinical features of paroxysmal symptoms occurring in 26 patients with multiple sclerosis are reviewed. The findings are considered to provide further support for the concept of lateral spread of axonal excitation within demyelinated plaques. Images

Matthews, W B

1975-01-01

81

Care Seeking after Stroke Symptoms  

PubMed Central

Objective To assess risk factors associated with seeking care for stroke symptoms. Methods Using data from the population-based national cohort study (REasons for Geographic And Racial Differences in Stroke) conducted January 25, 2003–February 28, 2007 (N = 23,664), we assessed care-seeking behavior among 3,668 participants who reported a physician diagnosis of stroke/transient ischemic attack (n = 647) or stroke symptoms (n = 3,021) during follow-up. Care seeking was defined as seeking medical attention after stroke symptoms or a physician diagnosis. Results Overall, 58.5% of participants (2,146/3,668) sought medical care. In multivariable models, higher income was associated with greater likelihood of seeking care ( p = 0.02): participants with income of ?$75,000 had odds 1.43 times (95% confidence interval [CI], 1.02–2.02) greater than those with income of less than $20,000. Diabetes and previous heart disease were associated with increased care seeking: odds ratio (OR) of 1.23 (95% CI, 1.04 –1.47) and OR of 1.26 (95% CI, 1.06– 1.49), respectively. Participants with previous stroke symptoms but no stroke history were less likely to seek care than those with stroke history or without previous symptoms (OR, 0.80; 95% CI, 0.67– 0.96). Past smoking was associated with lower likelihood (OR, 0.71; 95% CI, 0.59–0.85; p = 0.0003) of seeking care relative to nonsmokers. Interpretation Only approximately half of participants with stroke symptoms sought care. This is despite the encouragement of advocacy groups to seek prompt attention for stroke symptoms. Our results highlight the importance of identifying characteristics associated with care-seeking behavior. Recognizing factors that contribute to delays provides opportunities to enhance education on the importance of seeking care for stroke symptoms.

Howard, Virginia J.; Lackland, Daniel T.; Lichtman, Judith H.; McClure, Leslie A.; Howard, George; Wagner, Libby; Pulley, LeaVonne; Gomez, Camilo R.

2013-01-01

82

Juvenile Delinquency: Symptom or Syndrome?  

PubMed Central

Dr. Stephenson discusses juvenile delinquency as a symptom of a variety of underlying problems, a syndrome or a disease entity. She describes research carried out in Vancouver in which multiple factors were found to be concerned, with three major types of delinquents identified. Delinquency is seen to be a symptom of relatively healthy adolescent development, of social disturbance or emotional disturbance. The research was supported by National Health Grant 609-7-194.

Stephenson, P. Susan

1972-01-01

83

Psychometric study of the Neurobehavioral Symptom Inventory.  

PubMed

The Department of Veterans Affairs (VA) uses the Neurobehavioral Symptom Inventory (NSI) to measure postconcussive symptoms in its comprehensive traumatic brain injury (TBI) evaluation. This study examined the NSI's item properties, internal consistency, and external validity. Data were obtained from a federally funded study of the experiences of combat veterans. Participants included 500 Operations Iraqi and Enduring Freedom veterans, 219 of whom sustained at least one TBI. Data were collected at five VA medical centers and one VA outpatient clinic across upstate New York. Measures included neuropsychological interview, NSI, Beck Anxiety Inventory, Beck Depression Inventory-II, and Posttraumatic Stress Disorder Checklist-Military Version. The NSI demonstrated high internal consistency (total alpha = 0.95; subscale alpha = 0.88 to 0.92). Subscale totals based on Caplan et al.'s factor analysis correlated highly with the NSI total score (r = 0.88 to 0.93). NSI scores differentiated veterans with TBI history from those without but were strongly influenced by variance associated with probable posttraumatic stress disorder, depression, and generalized anxiety. Results suggest that the NSI is a reliable and valid measure of postconcussive symptoms. Scale validity is evident in the differentiation of TBI and non-TBI classifications. The scale domain is not limited to TBI, however, and extends to detection of probable effects of additional affective disorders prevalent in the veteran population. PMID:23299259

King, Paul R; Donnelly, Kerry T; Donnelly, James P; Dunnam, Mina; Warner, Gary; Kittleson, C J; Bradshaw, Charles B; Alt, Michelle; Meier, Scott T

2012-01-01

84

Effects of amino acid deletion and substitution on the chemical properties, biological activities of the frog peptide palustrin-OG1.  

PubMed

Palustrin-OG1 (OG1) is a host defense peptide isolated from the frog Odorrana grahami. In this study, we analyzed the chemical properties, antimicrobial activities and cytotoxicities of OG1 and its derivatives to identify the most promising peptide as an antimicrobial agent. By increasing the net positive charge, amphipathicity and decreasing the mean hydrophobicity of OG1, the derivative named as OG2 exerted higher antimicrobial activity against bacteria but lower cytotoxicity against both porcine erythrocytes and peripheral blood mononuclear cells than did OG1 (P<0.01). After substitution of Cys residues of OG2 by Ala or Trp residues, two derivatives named as OG2A and OG2W were less effective against bacteria and induced greater hemolysis than did OG2, indicating the importance of Cys residues. The substitution of the C-terminal Thr of OG2 resulted OG2N, which decreased the cytotoxicity and improved killing kinetics against gram-positive bacteria by the rapid damage of cell wall and membrane. PMID:23061668

Xie, Yong-Gang; Liu, Yi-Fan; Luan, Chao; Han, Fei-Fei; Lai, Ren; Groleau, Denis; Feng, Jie; Wang, Yi-Zhen

2013-07-01

85

Head and Neck Cancer: Symptoms and Signs  

MedlinePLUS

... 5/2013 Symptoms and Signs Cancer.Net Guide Head and Neck Cancer Overview Statistics Risk Factors and Prevention Symptoms ... on the side of your screen. People with head and neck cancer often experience the following symptoms or signs. ...

86

Predicting Symptom Return from Rate of Symptom Reduction in Cognitive–Behavior Therapy for Depression  

Microsoft Academic Search

Numerous studies have examined rates of symptom reduction and symptom return across treatment modalities; however, few studies have investigated the degree to which rate of symptom reduction during treatment is related to symptom return following treatment. We examined the relation between symptom return 3 and 6 months after completing treatment and several measures of symptom reduction during treatment, including amount

Darcy A. Santor; Zindel V. Segal

2001-01-01

87

Human symptoms-disease network.  

PubMed

In the post-genomic era, the elucidation of the relationship between the molecular origins of diseases and their resulting phenotypes is a crucial task for medical research. Here, we use a large-scale biomedical literature database to construct a symptom-based human disease network and investigate the connection between clinical manifestations of diseases and their underlying molecular interactions. We find that the symptom-based similarity of two diseases correlates strongly with the number of shared genetic associations and the extent to which their associated proteins interact. Moreover, the diversity of the clinical manifestations of a disease can be related to the connectivity patterns of the underlying protein interaction network. The comprehensive, high-quality map of disease-symptom relations can further be used as a resource helping to address important questions in the field of systems medicine, for example, the identification of unexpected associations between diseases, disease etiology research or drug design. PMID:24967666

Zhou, XueZhong; Menche, Jörg; Barabási, Albert-László; Sharma, Amitabh

2014-01-01

88

Symptom identification in the chronically critically ill.  

PubMed

Ascertaining the symptom experience of chronically critically ill (CCI) patients is difficult because of communication impairment and fluctuations in patient cognition and physiologic conditions. The use of checklist self-report ratings is hampered by the inability of most CCI patients to respond verbally to symptom queries. In addition to the communication problems caused by mechanical ventilation, the apparently diverse idioms of symptom expression add to the potential for miscommunication regarding symptom experience. Although patient communication impairment is a major barrier to symptom identification, symptom assessment and treatment are fundamental components of nursing care for CCI. This article reviews and describes the unique constellation of symptoms experienced by many critically ill patients. We report our observations of symptom communication among CCI patients and nurses and discuss inconsistency in the language of symptom expression among nurses and patients. Clinically applicable strategies to improve nurse-patient symptom communication and suggestions for refinement of symptom assessment in chronic critical illness are provided. PMID:20118706

Campbell, Grace B; Happ, Mary Beth

2010-01-01

89

[Symptoms and management of tetany].  

PubMed

Tetany is a series of symptoms characterized by painful muscle cramp that derives from enhanced neuromuscular excitability due to hypocalcemia, hypomagnesemia or alkalosis. In a broad sense, tetany includes associated sensory disturbance. Typical symptoms of tetany include carpopedal spasm, laryngospasm and generalized seizure. Chvostek and Trousseau signs are provocative tests for diagnosis of latent tetany. Many diseases including endocrine disorders like hypoparathyroidism and alkalosis by hyperventilation can cause tetany. Infusion of calcium or magnesium is effective as an acute therapy for tetany. However, subsequent diagnosis and treatment of underlining diseases are mandatory. PMID:17660621

Ito, Nobuaki; Fukumoto, Seiji

2007-08-01

90

Large scale variation in Enterococcus faecalis illustrated by the genome analysis of strain OG1RF  

Microsoft Academic Search

Background  \\u000a Enterococcus faecalis has emerged as a major hospital pathogen. To explore its diversity, we sequenced E. faecalis strain OG1RF, which is commonly used for molecular manipulation and virulence studies.\\u000a \\u000a \\u000a \\u000a \\u000a Results  The 2,739,625 base pair chromosome of OG1RF was found to contain approximately 232 kilobases unique to this strain compared\\u000a to V583, the only publicly available sequenced strain. Almost no mobile

Agathe Bourgogne; Danielle A Garsin; Xiang Qin; Kavindra V Singh; Jouko Sillanpaa; Shailaja Yerrapragada; Yan Ding; Shannon Dugan-Rocha; Christian Buhay; Hua Shen; Guan Chen; Gabrielle Williams; Donna Muzny; Arash Maadani; Kristina A Fox; Jason Gioia; Lei Chen; Yue Shang; Cesar A Arias; Sreedhar R Nallapareddy; Meng Zhao; Vittal P Prakash; Shahreen Chowdhury; Huaiyang Jiang; Richard A Gibbs; Barbara E Murray; Sarah K Highlander; George M Weinstock

2008-01-01

91

Autism and ADHD Symptoms in Patients with OCD: Are They Associated with Specific OC Symptom Dimensions or OC Symptom Severity?  

Microsoft Academic Search

In obsessive-compulsive disorder (OCD), the relationship between autism spectrum disorders (ASD), attention-deficit\\/hyperactivity\\u000a disorder (ADHD) symptom, and obsessive-compulsive (OC) symptom dimensions and severity has scarcely been studied. Therefore,\\u000a 109 adult outpatients with primary OCD were compared to 87 healthy controls on OC, ADHD and ASD symptoms. OCD patients showed\\u000a increased ADHD and autism symptom frequencies, OCD + ADHD patients reporting more autism symptoms

Gideon E. Anholt; Danielle C. Cath; Patricia van Oppen; Merijn Eikelenboom; Johannes H. Smit; Harold van Megen

2010-01-01

92

The Adoption of Systems Innovations in Educational Organizations: A Case Study of Operation Guidance.  

ERIC Educational Resources Information Center

To identify factors which affect the acceptance of innovation in school organizations, a career development product entitled Operation Guidance (OG) was the object of a case study. Five basic organizational characteristics were used to roughly quantify attributes of the organization of the six schools studied. The characteristics were:…

Kester, Ralph J.; Howard, John, Jr.

93

A Rating Scale for Psychotic Symptoms (RSPS)  

Microsoft Academic Search

The authors present a new rating scale for the psychotic symptoms of schizophrenia and related psychoses. The scale links specific symptoms of psychopathology to dysfunction and overactivity of dopaminergic mechanisms underlying the processes of reward and selective attention. The Rating Scale for Psychotic Symptoms (RSPS) is a 44-item rating instrument with a seven-point severity scale for each item. Psychotic symptoms

Guy Chouinard; Robert Miller

1999-01-01

94

[Psychiatric symptoms and coeliac disease].  

PubMed

Psychiatric symptoms and psychological behavioral pathologies are common in patients with untreated coeliac disease. There are several case reports of coexistence of coeliac sprue and depression, schizophrenia and anxiety. Views on association between coeliac disease and psychiatric disturbances and results of the most important studies are discussed. Biological background is referred. Malabsorption and deficiency of aminoacids and vitamins implicate reduction of synthesis of neurotransmitters in the central nervous system. Psychiatric symptoms could also be linked to immunological disregulation in coeliac patients. Psychological pathologies do appear in treated and untreated coeliacs, the need of psychological support is stressed. Coeliac disease should be taken into consideration in patients with psychiatric disorders, particularly if they are not responsive to psychopharmacological therapy, because withdrawal of gluten from the diet usually results in disappearance of symptoms. In recent years, an increased incidence of subclinical/silent coeliac disease has been reported. Psychiatric symptoms and psychological behavioral pathologies could be the only clinical manifestation of coeliac disease, but the epidemiological aspects need further investigation. PMID:12298186

Potocki, Pawe?; Hozyasz, Kamil

2002-01-01

95

Conditioning exercise decreases premenstrual symptoms  

Microsoft Academic Search

Summary  Conditioning exercise decreased premenstrual symptoms during 3 months of a prospective controlled training study. Eight women with normal ovulatory menstrual cycles began a running exercise training programme while completing intensity-graded questionnaires concerning molimina. Six sedentary control women followed the same protocol for 3 months but did not exercise. Oral basal temperatures evaluated by mean temperature analysis were obtained for all

J. C. Prior; Y. Vigna; N. Alojada

1986-01-01

96

Abrupt Zero-Preoxygenation Altitude Threshold for Decompression Sickness Symptoms.  

National Technical Information Service (NTIS)

The altitude threshold for decompression sickness (DCS) symptoms has been variously described as being 18,000 ft (5,487 m) to above 25,000 ft (7,620 m). Safety and efficiency of aerospace operations require more precise determination of the DCS threshold....

J. T. Webb A. A. Pilmanis R. B. O'Connor

1998-01-01

97

Enhanced fungal resistance in Arabidopsis expressing wild rice PR3 (OgChitIVa) encoding chitinase class IV  

Microsoft Academic Search

Oryza grandiglumis Chitinase IVa (OgChitIVa) cDNA encoding a class IV chitinase was cloned from wild rice (Oryza grandiglumis). OgChitIVa cDNA contains an open reading frame of 867 nucleotides encoding 288 amino acid residues with a predicted molecular weight\\u000a of 30.4 kDa and isoelectric point of 8.48. Deduced amino acid sequences of OgChitIVa include the signal peptide and chitin-binding domain in the

Jung-Hun Pak; Eun-Sook Chung; Sang-Hyun Shin; Eun-Hee Jeon; Mi-Jin Kim; Hye-Young Lee; Ji-Ung Jeung; Nam-In Hyung; Jai-Heon Lee; Young-Soo Chung

2009-01-01

98

Neuropsychiatric symptoms in Alzheimer's disease  

PubMed Central

Neuropsychiatric symptoms (NPS) are core features of Alzheimer’s disease and related dementias. Once thought to emerge primarily in people with late-stage disease, these symptoms are currently known to manifest commonly in very early disease and in prodromal phases, such as mild cognitive impairment. Despite decades of research, reliable treatments for dementia-associated NPS have not been found, and those that are in widespread use present notable risks for people using these medications. An Alzheimer’s Association Research Roundtable was convened in the spring of 2010 to review what is known about NPS in Alzheimer’s disease, to discuss classification and underlying neuropathogenesis and vulnerabilities, and to formulate recommendations for new approaches to tailored therapeutics.

Lyketsos, Constantine G.; Carrillo, Maria C.; Ryan, J. Michael; Khachaturian, Ara S.; Trzepacz, Paula; Amatniek, Joan; Cedarbaum, Jesse; Brashear, Robert; Miller, David S.

2012-01-01

99

Cataract Symptom Scale: clarifying measurement  

Microsoft Academic Search

Aim:Previous psychometric evaluation of the Cataract Symptom Scale (CSS) focused on classic assessments of reliability and validity. The aim was to investigate the psychometric properties of the CSS using the Rasch measurement model.Methods:243 patients drawn from the Flinders Eye Centre cataract surgery waiting-list self-administered the CSS. Rasch analysis was used to investigate the following properties of the CSS: measurement a

V K Gothwal; T A Wright; E L Lamoureux; K Pesudovs

2009-01-01

100

Gender, coping and psychosomatic symptoms.  

PubMed

In this study gender differences in coping were explored, using the Ways of Coping Checklist (WCC; Folkman & Lazarus, 1980). In addition, the focus was on sex differences in the predictive value of coping strategies in relation to psychosomatic symptoms. Males preferred problem-focused coping strategies, planned and rational actions, positive thinking, personal growth and humour, day-dreaming and fantasies. Women preferred emotion-focused coping solutions, self-blame, expression of emotions/seeking of social support, and wishful thinking/emotionality. In spite of the gender differences the results of multiple regression analyses indicated congruous relationships between coping and complaints for both sexes. Stressors and coping factors contributed in much the same way to the explained variance of symptoms and the results were generally similar for males and females. The present data also emphasize the bidirectionality of the coping-symptoms link. This holds especially for self-blame, day-dreaming and fantasizing, and wishful thinking/emotionality. In contrast, distancing was found to be associated with self-reported psychosocial load. Future prospective studies should explicitly pay attention to this bidirectional relationship. PMID:2320691

Vingerhoets, A J; Van Heck, G L

1990-02-01

101

The Impact of Depressive Symptoms in Adults with ADHD Symptoms on Family Function and ADHD Symptoms of Their Children  

PubMed Central

Objective People with attention-deficit/hyperactivity disorder (ADHD) exhibit considerable impairment in social, academic, or occupational functioning. The present study aimed to examine the patterns of associations between ADHD symptoms, depression, and family functioning. Methods The sample consisted of 1,022 adults randomly selected from a district in Seoul, South Korea. Several self-assessment scales were utilized to rate ADHD symptoms (both past and current), current symptoms of depression, and level of family functioning. ADHD symptoms in the children of these participants were also assessed. Pearson's correlation and multiple linear regression analyses were performed; structural equation modeling (SEM) was conducted to determine the best fitting model. Results Adult ADHD symptoms were positively associated with depressive symptoms. Depressive symptoms, in turn, mediated the relationship between adult ADHD symptoms and cohesion among family members. In addition, depressive symptoms mediated the relationship between adult ADHD symptoms and their children's ADHD symptoms. Conclusion The relationship between adult ADHD symptoms and family dysfunction may be influenced by depressive symptoms. When treating ADHD in adults, clinicians should pay attention to the presence or absence of depression.

Hong, Soon-Beom; Lee, Jong-Ha; Chun, Duk Hee; Shin, Min-Sup; Yoo, Hee-Jeong; Kim, Boong-Nyun; Cho, Soo-Churl

2014-01-01

102

Pain and other symptoms in cancer survivors.  

PubMed

ABSTRACT Pain is common in cancer survivors. Long-term pain, often of neuropathic origin, is common after operations, radiotherapy, and chemotherapy. Pain and other concomitant symptoms and side effects should be assessed with validated and reliable scales and questionnaires. Cancer survivors with severe pain should be seen by a pain specialist. Multidisciplinary rehabilitation and individualized pain management may improve quality of life in cancer survivors. Four case reports are presented to illustrate this. This report is adapted from paineurope 2013; Issue 4, ©Haymarket Medical Publications Ltd., and is presented with permission. paineurope is provided as a service to pain management by Mundipharma International, Ltd., and is distributed free of charge to health care professionals in Europe. Archival issues can be accessed via the Web site: http://www.paineurope.com , at which European health professionals can register online to receive copies of the quarterly publication. PMID:24801977

Westerling, Dagmar

2014-06-01

103

Autism and ADHD symptoms in patients with OCD: are they associated with specific OC symptom dimensions or OC symptom severity?  

PubMed

In obsessive-compulsive disorder (OCD), the relationship between autism spectrum disorders (ASD), attention-deficit/hyperactivity disorder (ADHD) symptom, and obsessive-compulsive (OC) symptom dimensions and severity has scarcely been studied. Therefore, 109 adult outpatients with primary OCD were compared to 87 healthy controls on OC, ADHD and ASD symptoms. OCD patients showed increased ADHD and autism symptom frequencies, OCD + ADHD patients reporting more autism symptoms (particularly attention switching and social skills problems) than OCD - ADHD patients. Attention switching problems were most significant predictors of OC symptom dimensions (except hoarding) and of symptom severity. Hoarding was not associated with elevated autism scale scores, but with inattention. In conclusion, attention switching problems may reflect both symptom overlap and a common etiological factor underlying ASD, ADHD and OCD. PMID:20039111

Anholt, Gideon E; Cath, Danielle C; van Oppen, Patricia; Eikelenboom, Merijn; Smit, Johannes H; van Megen, Harold; van Balkom, Anton J L M

2010-05-01

104

Mindfulness Is Associated with Fewer PTSD Symptoms, Depressive Symptoms, Physical Symptoms, and Alcohol Problems in Urban Firefighters  

ERIC Educational Resources Information Center

Objective: This study investigated the association between mindfulness, other resilience resources, and several measures of health in 124 urban firefighters. Method: Participants completed health measures of posttraumatic stress disorder (PTSD) symptoms, depressive symptoms, physical symptoms, and alcohol problems and measures of resilience…

Smith, Bruce W.; Ortiz, J. Alexis; Steffen, Laurie E.; Tooley, Erin M.; Wiggins, Kathryn T.; Yeater, Elizabeth A.; Montoya, John D.; Bernard, Michael L.

2011-01-01

105

Postural tachycardia syndrome is associated with significant symptoms and functional impairment predominantly affecting young women: a UK perspective  

PubMed Central

Objective To examine a large UK cohort of patients with postural tachycardia syndrome (PoTS), to compare demographic characteristics, symptoms and treatment of PoTS at one centre compared to the largest patient group PoTS UK and to verify if their functional limitation is similar to patients with chronic fatigue syndrome (CFS). Design A cross-sectional study assessed the frequency of symptoms and their associated variables. Patients and setting Two PoTS cohorts were: (1) recruited via PoTS UK, (2) diagnosed at Newcastle Hospitals National Health Service (NHS) Foundation Trust 2009–2012. Patients with PoTS were then compared to a matched cohort with CFS. Main outcome measures Patients’ detailed demographics, time to diagnosis, education, disability, medications, comorbidity and precipitants. Symptom assessment tools captured, Fatigue Impact Scale, Epworth Sleepiness Scale, Orthostatic Grading Scale (OGS), Hospital Anxiety and Depression Scale, Health Assessment Questionnaire, Cognitive Failures Questionnaire. Results 136 patients with PoTS participated (84 members of PoTS UK (170 cohort; 50% return) and 52 (87 cohort; 60%) from Newcastle Clinics). The PoTS UK population was significantly younger than the clinic patients, with significantly fewer men (p=0.005). Over 60% had a university or postgraduate degree. Significantly more of the PoTS UK cohort were working, with hours worked being significantly higher (p=0.001). Time to diagnosis was significantly longer in the PoTS UK cohort (p=0.04). Symptom severity was comparable between cohorts. The PoTS total group was compared with a matched CFS cohort; despite comparable levels of fatigue and sleepiness, autonomic symptom burden (OGS) was statistically significantly higher. The most common treatment regime included ?-blockers. Overall, 21 treatment combinations were described. Up to 1/3 were taking no treatment. Conclusions Patients with PoTS are predominantly women, young, well educated and have significant and debilitating symptoms that impact significantly on quality of life. Despite this, there is no consistent treatment.

McDonald, Claire; Koshi, Sharon; Busner, Lorna; Kavi, Lesley; Newton, Julia L

2014-01-01

106

Startle reactivity and PTSD symptoms in a community sample of women  

Microsoft Academic Search

Exaggerated startle and PTSD symptoms have been investigated primarily in relation to acute or Type I stressors. The present study examined PTSD symptoms and startle eyeblink response in relation to chronic or Type II stressors. Type II stressors were operationally defined as high levels of childhood corporal punishment and high levels of current partner aggression. This study recruited a sample

Anna Marie Medina; Veronica Y. Mejia; Anne M. Schell; Michael E. Dawson; Gayla Margolina

2001-01-01

107

Managing Menopausal Symptoms in Breast Cancer Survivors.  

National Technical Information Service (NTIS)

Menopausal symptoms commonly occur in breast cancer survivors. In this research program we evaluated the efficacy of a comprehensive menopausal assessment (CMA) and intervention program for management of menopausal symptoms (hot flashes, vaginal dryness, ...

P. A. Ganz

1999-01-01

108

Glaucoma: Symptoms, Diagnosis, Treatment and Latest Research  

MedlinePLUS

... Feature: Glaucoma Glaucoma: Symptoms, Diagnosis, Treatment and Latest Research Past Issues / Fall 2009 Table of Contents Symptoms ... patients may need to keep taking drugs. Latest Research Researchers are studying the causes of glaucoma, looking ...

109

Symptoms and Diagnosis of Metabolic Syndrome  

MedlinePLUS

... Tools & Resources Stroke More Symptoms and Diagnosis of Metabolic Syndrome Updated:Mar 13,2014 What are the symptoms ... content was last reviewed on 07/11/2011. Metabolic Syndrome • Home • About Metabolic Syndrome • Why Metabolic Syndrome Matters • ...

110

Retinal Detachment: Torn or Detached Retina Symptoms  

MedlinePLUS

... News Consumer Alerts Retinal Detachment: Torn or Detached Retina Symptoms Tweet Symptoms of a retinal tear and ... your vision. What Is A Torn Or Detached Retina? Torn Or Detached Retina Causes Torn Or Detached ...

111

Signs and Symptoms of Mood Disorders  

MedlinePLUS

... your family's history. Signs and symptoms of bipolar disorder Bipolar disorder differs significantly from clinical depression, although the ... or restlessness. Symptoms of mania - the "highs" of bipolar disorder Increased physical and mental activity and energy Heightened ...

112

Introduction to Symptoms of Eye Disorders  

MedlinePLUS

... Resources for Help and Information The One-Page Merck Manual of Health Medical Terms Conversion Tables Manuals ... the Eyes Vision Loss, Sudden Other Eye Symptoms Merck Manual > Patients & Caregivers > Eye Disorders > Symptoms of Eye ...

113

Somatic symptom reporting in women and men  

Microsoft Academic Search

Women report more intense, more numerous, and more frequent bodily symptoms than men. This difference appears in samples of\\u000a medical patients and in community samples, whether or not gynecologic and reproductive symptoms are excluded, and whether\\u000a all bodily symptoms or only those which are medically unexplained are examined. More limited, but suggestive, literature on\\u000a experimental pain, symptom reporting in childhood,

Arthur J. Barsky; Heli M. Peekna; Jonathan F. Borus

2001-01-01

114

Manic symptoms and impulsivity during bipolar depressive episodes  

PubMed Central

Objectives In contrast to the extensive literature on the frequent occurrence of depressive symptoms in manic patients, there is little information about manic symptoms in bipolar depressions. Impulsivity is a prominent component of the manic syndrome, so manic features during depressive syndromes may be associated with impulsivity and its consequences, including increased risk of substance abuse and suicidal behavior. Therefore, we investigated the prevalence of manic symptoms and their relationships to impulsivity and clinical characteristics in patients with bipolar depressive episodes. Methods In 56 bipolar I or II depressed subjects, we investigated the presence of manic symptoms, using Mania Rating Scale (MRS) scores from the Schedule for Affective Disorders and Schizophrenia (SADS), and examined its association with other psychiatric symptoms (depression, anxiety, and psychosis), age of onset, history of alcohol and/or other substance abuse and of suicidal behavior, and measures of impulsivity. Results MRS ranged from 0 to 29 (25th–75th percentile, range 4–13), and correlated significantly with anxiety and psychosis, but not with depression, suggesting the superimposition of a separate psychopathological mechanism. Impulsivity and history of substance abuse, head trauma, or suicide attempt increased with increasing MRS. Receiver-operating curve analysis showed that MRS could divide patients into two groups based on history of alcohol abuse and suicide attempt, with an inflection point corresponding to an MRS score of 6. Discussion Even modest manic symptoms during bipolar depressive episodes were associated with greater impulsivity, and with histories of alcohol abuse and suicide attempts. Manic symptoms during depressive episodes suggest the presence of a potentially dangerous combination of depression and impulsivity.

Swann, Alan C; Moeller, F Gerard; Steinberg, Joel L; Schneider, Laurie; Barratt, Ernest S; Dougherty, Donald M

2009-01-01

115

Depressive Symptoms Among Hospitalized Patients in Israel  

Microsoft Academic Search

Depressive symptoms are common among hospitalized patients and can indicate more serious problems. This study examined the level of depressive symptoms among patients in one hospital in Jerusalem, the variables related to depression, and the extent to which social workers provided services to those patients. Over 60% of patients reported high levels of depressive symptoms. Levels were higher among Arabs,

Gail K. Auslander

2012-01-01

116

Somatic symptom progression in idiopathic Parkinson's disease  

Microsoft Academic Search

The substantia nigra (SN) pars compacta is arranged somatotopically. Symptoms of idiopathic Parkinson's disease (IPD) are caused by a lesion in this nucleus, which spreads in a stereotyped spatio-temporal pattern during the course of the disease. We investigated the order of somatic symptom progression in a group of 30 patients with IPD to determine if progression of symptoms was consistent

Jon M. Dickson; Richard A. Grünewald

2004-01-01

117

Mastocytosis: Mediator-Related Signs and Symptoms  

Microsoft Academic Search

Patients with systemic mastocytosis present symptoms related to the tissue response to the release of mediators from mast cells and to the local mast cell burden. Such patients often have a history of chronic and acute mediator-related symptoms. Most patients have indolent disease with a good prognosis and a normal life span. Symptoms can include pruritus, flushing, syncope, gastric distress,

Mariana Castells; K. Frank Austen

2002-01-01

118

Symptom Structure of PTSD Following Breast Cancer  

Microsoft Academic Search

Identification of posttraumatic stress disorder (PTSD) symptoms and diagnoses in survivors of cancer is a growing area of research, but no published data exist regarding the symptom structure of PTSD in survivors of malignant disease. Findings from investigations of the PTSD symptom structure in other trauma populations have been inconsistent and have not been concordant with the reexperiencing, avoidance\\/numbing, and

Matthew J. Cordova; Jamie L. Studts; Danette M. Hann; Paul B. Jacobsen; Michael A. Andrykowski

2000-01-01

119

Importance of reflux symptoms in functional dyspepsia  

Microsoft Academic Search

The relation between symptom severity in gastro-oesophageal reflux disease (GORD) and quantitated oesophageal acid reflux is variable. Furthermore, when oesophageal acid exposure lies within the conventional normal range, the cause of the symptoms is unknown. This prospective study evaluated 24 hour ambulatory oesophageal pH profiles in relation to objective symptom scores in 100 dyspeptic patients who were free from ulcer

P K Small; M A Loudon; B Waldron; D Smith; F C Campbell

1995-01-01

120

Postoperative nasal symptoms associated with an endoscopic endonasal transsphenoidal approach.  

PubMed

Recent studies have indicated the usefulness of endoscopic endonasal transsphenoidal approach (EETSA). A few studies have reported on the postoperative nasal symptoms of patients who have undergone EETSA. Therefore, we adopted a rhinologic perspective to compare preoperative and postoperative nasal symptoms after performing a binostril, four-hand EETSA. Patients who were scheduled to undergo binostril, four-hand EETSA underwent preoperative nasal evaluation using the Nasal Obstruction Symptom Evaluation (NOSE), Sino-Nasal Outcome Test-20 (SNOT-20), and a visual analogue scale (VAS) to assess several nasal symptoms. Repeat testing was performed 6 months postoperatively. Paired Student's t tests were used to compare preoperative and postoperative scores. A total of 142 patients who underwent a binostril, four-hand EETSA were included in this study. We found no statistically significant differences between preoperative and postoperative NOSE, total SNOT-20 scores, or scores on the VAS for nasal obstruction, sneezing, rhinorrhea, snoring, or facial pain. However, VAS of olfactory change increased significantly after EETSA (p < 0.05). The binostril, four-hand EETSA would be a useful method because it permits operative manipulability and a wide visual field for skull base lesions. However, rhinologists must consider postoperative nasal symptoms and perform a proper preoperative examination, especially with regard to the olfactory function, and inform patients scheduled for EETSA of potential postoperative changes. PMID:23081674

Kim, Boo-Young; Son, Hye Lim; Kang, Seok-Gu; Kim, Sung Won; Hong, Yong Kil; Jeun, Sin-Soo; Kim, Soo Whan; Cho, Jin Hee; Park, Yong Jin

2013-03-01

121

Eating disorder symptoms and parenting styles.  

PubMed

This study aimed to examine associations between symptoms of eating disorders and parenting style, in a non-clinical sample. One hundred and five mothers completed self-report measures of eating disorder symptoms and parenting style. Higher levels of eating disorder symptoms were associated with more authoritarian and permissive parenting styles. Authoritative parenting was not significantly related to eating disorder symptoms. The findings demonstrate that eating disorder symptoms in non-clinical individuals are related to less adaptive parenting styles. These findings have potential implications for clinicians working with mothers with eating disorders. PMID:19932143

Haycraft, Emma; Blissett, Jackie

2010-02-01

122

Depressive Symptoms Among Immigrant Latino Sexual Minorities  

PubMed Central

Objective To estimate the prevalence and identify correlates of depressive symptoms among immigrant Latino sexual minorities. Methods Respondent-driven sampling (RDS) was used to estimate the prevalence of depressive symptoms, and univariate and multivariable analyses were conducted to identify correlates of depressive symptoms. Results Unweighted and RDS-weighted prevalence estimates of depressive symptoms were 69.2% and 74.8%, respectively. In the multivariable analysis, low social support, sexual compulsivity, and high self-esteem were significantly associated with increased depressive symptoms. Conclusions A need exists for culturally congruent mental health services for immigrant Latino sexual minorities in the southern United States.

Rhodes, Scott D.; Martinez, Omar; Song, Eun-Young; Daniel, Jason; Alonzo, Jorge; Eng, Eugenia; Duck, Stacy; Downs, Mario; Bloom, Fred R.; Allen, Alex Boeving; Miller, Cindy; Reboussin, Beth

2014-01-01

123

Concussion Symptom Inventory: An Empirically Derived Scale for Monitoring Resolution of Symptoms Following Sport-Related Concussion  

PubMed Central

Self-report post-concussion symptom scales have been a key method for monitoring recovery from sport-related concussion, to assist in medical management, and return-to-play decision-making. To date, however, item selection and scaling metrics for these instruments have been based solely upon clinical judgment, and no one scale has been identified as the “gold standard”. We analyzed a large set of data from existing scales obtained from three separate case–control studies in order to derive a sensitive and efficient scale for this application by eliminating items that were found to be insensitive to concussion. Baseline data from symptom checklists including a total of 27 symptom variables were collected from a total of 16,350 high school and college athletes. Follow-up data were obtained from 641 athletes who subsequently incurred a concussion. Symptom checklists were administered at baseline (preseason), immediately post-concussion, post-game, and at 1, 3, and 5 days post-injury. Effect-size analyses resulted in the retention of only 12 of the 27 variables. Receiver-operating characteristic analyses were used to confirm that the reduction in items did not reduce sensitivity or specificity. The newly derived Concussion Symptom Inventory is presented and recommended as a research and clinical tool for monitoring recovery from sport-related concussion.

Randolph, Christopher; Millis, Scott; Barr, William B.; McCrea, Michael; Guskiewicz, Kevin M.; Hammeke, Thomas A.; Kelly, James P.

2009-01-01

124

The Link Between Depression and Physical Symptoms  

PubMed Central

Physical symptoms are common in depression, and, in fact, vague aches and pain are often the presenting symptoms of depression. These symptoms include chronic joint pain, limb pain, back pain, gastrointestinal problems, tiredness, sleep disturbances, psychomotor activity changes, and appetite changes. A high percentage of patients with depression who seek treatment in a primary care setting report only physical symptoms, which can make depression very difficult to diagnose. Physical pain and depression have a deeper biological connection than simple cause and effect; the neurotransmitters that influence both pain and mood are serotonin and norepinephrine. Dysregulation of these transmitters is linked to both depression and pain. Antidepressants that inhibit the reuptake of both serotonin and norepinephrine may be used as first-line treatments in depressed patients who present with physical symptoms. Many physicians consider patients to be in remission when their acute emotional symptoms have abated, but residual symptoms—including physical symptoms—are very common and increase the likelihood of relapse. All symptoms must be measured in order to achieve full remission. There are a number of short yet accurate measurement tools (rating scales) available that effectively measure the remission of physical symptoms as well as emotional symptoms.

Trivedi, Madhukar H.

2004-01-01

125

Self-Reported ADHD Symptoms among College Students: Item Positioning Affects Symptom Endorsement Rates  

ERIC Educational Resources Information Center

Objective: The effect of manipulating item positioning on self-reported ADHD symptoms was examined. We assessed whether listing DSM-IV ADHD symptoms serially or interspersed affected (a) the correlation between ADHD symptoms and (b) the rate of symptom endorsement. Method: In Study 1, an undergraduate sample (n = 102) completed a measure that…

Mitchell, John T.; Knouse, Laura E.; Nelson-Gray, Rosemery O.; Kwapil, Thomas R.

2009-01-01

126

Symptoms, personality traits, and stress in people with mobile phone-related symptoms and electromagnetic hypersensitivity  

Microsoft Academic Search

ObjectiveSome people report symptoms that they associate with electromagnetic field (EMF) exposure. These symptoms may be related to specific EMF sources or to electrical equipment in general (perceived electromagnetic hypersensitivity, EHS). Research and clinical observations suggest a difference between mobile phone (MP)-related symptoms and EHS with respect to symptom prevalence, psychological factors, and health prognosis. This study assessed prevalence of

Amanda Johansson; Steven Nordin; Marina Heiden; Monica Sandström

2010-01-01

127

Borderline Personality Disorder: Are Proliferative Symptoms Characteristic?  

PubMed Central

Borderline personality is an Axis II disorder that has historically encompassed a number of different psychiatric symptoms. In empirical studies, these multiple psychiatric symptoms appear to manifest as numerous comorbid Axis I and II diagnoses. In echoing these findings in primary care settings, individuals with borderline personality exhibit prolific somatic symptoms. Rather than the type of symptom, are the number of symptoms suggestive of this disorder, such that proliferative psychiatric or medical symptoms are diagnostically relevant? We discuss these issues and conclude that the number of symptoms is an unacknowledged but important diagnostic feature in borderline personality disorder. This ongoing column is dedicated to the challenging clinical interface between psychiatry and primary care—two fields that are inexorably linked.

Sansone, Randy A.; Sansone, Lori A.

2008-01-01

128

Development and Validation of an Instrument for Rapidly Assessing Symptoms: The General Symptom Distress Scale  

PubMed Central

Context Symptom assessment has increasingly focused on the evaluation of total symptom distress or burden rather than assessing only individual symptoms. The challenge for clinicians and researchers alike is to assess symptoms, determine the symptom distress associated with the symptoms, and the patient’s ability for symptom management without a lengthy and burdensome assessment process. Objectives The objective of this article is to discuss the psychometric evaluation of a brief general symptom distress scale developed to assess specific symptoms and how they rank in relation to each other, the overall symptom distress associated with the symptom schema, and provide an assessment of how well or poorly that symptom schema is managed. Methods Results from a pilot study about the initial development of the General Symptom Distress Scale (GSDS) with 76 hospitalized patients are presented, followed by a more complete psychometric evaluation of the GSDS using three samples of cancer patients (n=190) and their social network members, called partners in these studies (n=94). Descriptive statistics were used to describe the GSDS symptoms, symptom distress and symptom management. Point biserial correlations indexed the associations between dichotomous symptoms and continuous measures, and conditional probabilities were used to illustrate the substantial comorbidities of this sample. Internal consistency was examined using the KR-20 coefficient, and test-retest reliability was examined. Construct validity and predictive validity were also examined. Results The GSDS demonstrated satisfactory internal consistency and test-retest reliability, and good construct validity and predictive validity. The total score on the GSDS, symptom distress and symptom management correlated significantly with related constructs of depression, positive and negative affect and general health. The GSDS was able to demonstrate its ability to distinguish between those with or without chronic illness, and was able to significantly predict scores on criterion measures such as depression. Conclusion Collectively, these results suggest that the GSDS is a straightforward and useful instrument for rapidly assessing symptoms that can disrupt health-related quality of life.

Badger, Terry A.; Segrin, Chris; Meek, Paula

2010-01-01

129

Activation of defense response pathways by OGs and Flg22 elicitors in Arabidopsis seedlings  

PubMed Central

We carried out transcriptional profiling analysis in 10 day-old Arabidopsis thaliana seedlings treated with oligogalacturonides (OGs), oligosaccharides derived from the plant cell wall, or the bacterial flagellin peptide Flg22, general elicitors of the basal defense response in plants. Although detected by different receptors, both OGs and Flg22 trigger a fast and transient response that is both similar and comprehensive, and characterized by activation of early stages of multiple defense signaling pathways, particularly JA-associated processes. However, the response to Flg22 is stronger in both the number of genes differentially expressed and the amplitude of change. The magnitude of induction of individual genes is in both cases dose dependent, but even at very high concentrations, OGs do not induce a response that is as comprehensive as that seen with Flg22. While high doses of either microbe-associated molecular pattern (MAMP) elicit a late response that includes activation of senescence processes, SA-dependent secretory pathway genes and PR1 expression are substantially induced only by Flg22. These results suggest a lower threshold for activation of early responses than for sustained or SA-mediated late defenses. Expression patterns of aminocyclopropane-carboxylate synthase genes also implicate ethylene biosynthesis in regulation of the late innate immune response.

Denoux, Carine; Galletti, Roberta; Mammarella, Nicole; Gopalan, Suresh; Werck, Daniele; De Lorenzo, Giulia; Ferrari, Simone; Ausubel, Frederick M.; Dewdney, Julia

2010-01-01

130

Time Course of Symptom Disappearance after Microvascular Decompression for Hemifacial Spasm  

PubMed Central

Objective This study is to investigate time course of symptom disappearance in patients whose spasm relieved completely after microvascular decompression (MVD). Methods Of 115 patients with hemifacial spasm (HFS) who underwent MVD from April 2003 to December 2006, 89 patients who had no facial paralysis after operation and showed no spasm at last follow-up more than 1.5 years after operation were selected. Symptom disappearance with time after MVD was classified into type 1 (symptom disappearance right after operation), type 2 (delayed symptom disappearance) and type 3 (unusual symptom disappearance). Type 2 was classified into type 2a (with postoperative silent period) and type 2b (without silent period). Results Type 1, type 2a, type 2b and type 3 were 38.2%, 48.37%, 12.4% and 1.1%, respectively. Delayed disappearance group (type 2) was 60.7%. Post-operative symptom duration in all cases ranged from 0 to 900 days, average was 74.6 days and median was 14 days. In case of type 2, average post-operative symptom duration was 115.1 days and median was 42 days. Five and 3 patients required more than 1 year and 2 years, respectively, until complete disappearance of spasm. In type 2a, postoperative silent period ranged from 1 to 10 days, with an average of 2.4 days. Conclusion Surgeons should be aware that delayed symptom disappearance after MVD for HFS is more common than it has been reported, silent period can be as long as 10 days and time course of symptom disappearance is various as well as unpredictable.

Oh, Eun-Tak; Hyun, Dong-Keun; Yoon, Seung Hwan; Park, Hyeonseon; Park, Hyung-Chun

2008-01-01

131

Ectopic expression of ubiquitin-conjugating enzyme gene from wild rice, OgUBC1, confers resistance against UV-B radiation and Botrytis infection in Arabidopsis thaliana  

SciTech Connect

Highlights: Black-Right-Pointing-Pointer We isolated a novel E2 ubiquitin-conjugating enzyme from leaves of wild rice plants. Black-Right-Pointing-Pointer The OgUBC1 was highly expressed in leaves treated with SA and UV-B radiation. Black-Right-Pointing-Pointer The recombinant OgUBC1 has an enzymatic activity of E2 in vitro. Black-Right-Pointing-Pointer The OgUBC1 could protect disruption of plant cells by UV-B radiation. Black-Right-Pointing-Pointer OgUBC1 confers disease resistance and UV-B tolerance in transgenic Arabidopsis plants. -- Abstract: A previously unidentified gene encoding ubiquitin-conjugating enzyme was isolated from leaves of wild rice plant treated with wounding and microbe-associated molecular patterns. The OgUBC1 gene was composed of 148 amino acids and contained a typical active site and 21 ubiquitin thioester intermediate interaction residues and 4 E3 interaction residues. Both exogenous application of salicylic acid and UV-B irradiation triggered expression of OgUBC1 in leaves of wild rice. Recombinant OgUBC1 proteins bound to ubiquitins in vitro, proposing that the protein might act as E2 enzyme in planta. Heterologous expression of the OgUBC1 in Arabidopsis thaliana protected plants from cellular damage caused by an excess of UV-B radiation. A stable expression of chalcone synthase gene was detected in leaves of OgUBC1-expressing Arabidopsis, resulting in producing higher amounts of anthocyanin than those in wild-type Col-0 plants. Additionally, both pathogenesis-related gene1 and 5 were transcribed in the transgenic Arabidopsis in the absence of pathogen infection. The OgUBC1-expressing plants were resistant to the infection of Botrytis cinerea. Taken together, we suggested that the OgUBC1 is involved in ubiquitination process important for cellular response against biotic and abiotic stresses in plants.

Jeon, En Hee; Pak, Jung Hun; Kim, Mi Jin; Kim, Hye Jeong [Department of Genetic Engineering, Dong-A University, Busan 604-714 (Korea, Republic of)] [Department of Genetic Engineering, Dong-A University, Busan 604-714 (Korea, Republic of); Shin, Sang Hyun [National Crop Experiment Station, Rural Development Administration, Suwon 441-100 (Korea, Republic of)] [National Crop Experiment Station, Rural Development Administration, Suwon 441-100 (Korea, Republic of); Lee, Jai Heon; Kim, Doh Hoon; Oh, Ju Sung [Department of Genetic Engineering, Dong-A University, Busan 604-714 (Korea, Republic of)] [Department of Genetic Engineering, Dong-A University, Busan 604-714 (Korea, Republic of); Oh, Boung-Jun [BioControl Center, Jeonnam 516-942 (Korea, Republic of)] [BioControl Center, Jeonnam 516-942 (Korea, Republic of); Jung, Ho Won, E-mail: hwjung@dau.ac.kr [Department of Genetic Engineering, Dong-A University, Busan 604-714 (Korea, Republic of); Chung, Young Soo, E-mail: chungys@dau.ac.kr [Department of Genetic Engineering, Dong-A University, Busan 604-714 (Korea, Republic of)

2012-10-19

132

Prevention of depressive symptoms in school children.  

PubMed

This paper describes the development and preliminary efficacy of a program designed to prevent depressive symptoms in at-risk 10-13 year-olds, and relates the findings to the current understanding of childhood depression. The treatment targets depressive symptoms and related difficulties such as conduct problems, low academic achievement, low social competence, and poor peer relations, by proactively teaching cognitive techniques. Children were identified as 'at-risk' based on depressive symptoms and their reports of parental conflict. Sixty-nine children participated in treatment groups and were compared to 73 children in control groups. Depressive symptoms were significantly reduced and classroom behavior was significantly improved in the treatment group as compared to controls at post-test. Six-month follow-up showed continued reduction in depressive symptoms, as well as significantly fewer externalizing conduct problems, as compared to controls. The reduction in symptoms was most pronounced in the children who were most at risk. PMID:7993324

Jaycox, L H; Reivich, K J; Gillham, J; Seligman, M E

1994-11-01

133

Symptom Patterns Among Gulf War Registry Veterans  

PubMed Central

Objectives. We identify symptom patterns among veterans who believe they suffer from Gulf War–related illnesses and characterize groups of individuals with similar patterns. Methods. A mail survey was completed by 1161 veterans drawn from the Gulf War Health Registry. Results. An exploratory factor analysis revealed 4 symptom factors. A K-means cluster analysis revealed 2 groups: (1) veterans reporting good health and few moderate/severe symptoms, and (2) veterans reporting fair/poor health and endorsing an average of 37 symptoms, 75% as moderate/severe. Those in Cluster 2 were more likely to report having 1 or more of 24 medical conditions. Conclusions. These findings are consistent with previous investigations of symptom patterns in Gulf War veterans. This multisymptom illness may be more fully characterized by the extent, breadth, and severity of symptoms reported.

Hallman, William K.; Kipen, Howard M.; Diefenbach, Michael; Boyd, Kendal; Kang, Han; Leventhal, Howard; Wartenberg, Daniel

2003-01-01

134

Treating Psychotic Symptoms in Elderly Patients  

PubMed Central

Research has shown that elderly patients are especially at risk for the development of psychotic symptoms. A combination of factors contributes to the increased risk for psychosis in this patient population. Various DSM-IV diagnostic categories including delirium, schizophrenia, delusional disorder, mood disorders, dementia, substance abuse, and medical-neurologic conditions can be associated with psychotic symptoms. In general, medications are prescribed for specific target symptoms, started at low doses, and titrated gradually. Although buspirone, trazodone, valproic acid, and carbamazepine have been used with some success, antipsychotic medications have been the primary treatment of psychosis in the elderly. Because the atypical antipsychotics offer effective management of psychotic symptoms combined with low liability of extrapyramidal symptoms, these agents may be the current treatment of choice for psychotic symptoms in the elderly when used cautiously.

Targum, Steven D.

2001-01-01

135

Factors that Distinguish Symptoms of Most Concern to Parents from Other Symptoms of Dying Children  

PubMed Central

In a previous study, we conducted telephone interviews with parents 6 to 10 months after their child's death from cancer, using open-ended questions to identify the type and frequency of cancer-related symptoms that most concerned them during the last week of their child's life. Because the parents identified many clinically striking symptoms (n=109) that were not of most concern to them, we conducted a secondary analysis of these interviews (48 mothers and four fathers of 52 patients) to identify descriptive factors associated with the parents' level of concern. Six descriptive factors were associated with symptoms of most concern and 10 factors with symptoms not of most concern. Ten of these 16 factors occurred in both categories, indicating that clinicians should directly query parents to identify the symptoms that concern parents the most. Six factors differed between the two categories, and only one (the continuous distress caused by a symptom that is unrelieved) was unique to the category of symptoms of most concern. Five factors (symptom present for at least one week, symptom not seen as remarkable by the parent or causing no distress to the child, symptom well managed, symptom improved, and symptoms for which the parent felt adequately prepared) were unique to the category of symptoms not of most concern. By inquiring about symptoms of most concern and factors that influence parental concern, clinicians may be better able to direct care efforts to reduce patients' and parents' distress and support parents during the difficult end-of-life period.

Pritchard, Michele; Burghen, Elizabeth A.; Gattuso, Jami S.; West, Nancy K.; Gajjar, Poorna; Srivastava, Deo Kumar; Spunt, Sheri L.; Baker, Justin N.; Kane, Javier R.; Furman, Wayne L.; Hinds, Pamela S.

2010-01-01

136

The Nested Structure of Cancer Symptoms: Implications for Analyzing Co-occurrence and Managing Symptoms  

PubMed Central

Summary Objective Although many cancer patients experience multiple concurrent symptoms, most studies have either focused on the analysis of single symptoms, or have used methods such as factor analysis that make a priori assumptions about how the data is structured. This article addresses both limitations by first visually exploring the data to identify patterns in the co-occurrence of multiple symptoms, and then using those insights to select and develop quantitative measures to analyze and validate the results. Methods We used networks to visualize how 665 cancer patients reported 18 symptoms, and then quantitatively analyzed the observed patterns using degree of symptom overlap between patients, degree of symptom clustering using network modularity, clustering of symptoms based on agglomerative hierarchical clustering, and degree of nestedness of the symptoms based on the most frequently co-occurring symptoms for different sizes of symptom sets. These results were validated by assessing the statistical significance of the quantitative measures through comparison with random networks of the same size and distribution. Results The cancer symptoms tended to co-occur in a nested structure, where there was a small set of symptoms that co-occurred in many patients, and progressively larger sets of symptoms that co-occurred among a few patients. Conclusions These results suggest that cancer symptoms co-occur in a nested pattern as opposed to distinct clusters, thereby demonstrating the value of exploratory network analyses to reveal complex relationships between patients and symptoms. The research also extends methods for exploring symptom co-occurrence, including methods for quantifying the degree of symptom overlap and for examining nested co-occurrence in co-occurrence data. Finally, the analysis also suggested implications for the design of systems that assist in symptom assessment and management. The main limitation of the study was that only one dataset was considered, and future studies should attempt to replicate the results in new data.

Bhavnani, Suresh K.; Bellala, Gowtham; Ganesan, Arunkumaar; Krishna, Rajeev; Saxman, Paul; Scott, Clayton; Silveira, Maria; Given, Charles

2013-01-01

137

What Are the Signs and Symptoms of Heart Disease?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of Heart Disease? The signs and symptoms of coronary heart ... will have signs and symptoms of the disease. Heart Disease Signs and Symptoms The illustration shows the ...

138

Male hypogonadism: Symptoms and treatment  

PubMed Central

Male hypogonadism is a condition in which the body does not produce enough of the testosterone hormone; the hormone that plays a key role in masculine growth and development during puberty. There is a clear need to increase the awareness of hypogonadism throughout the medical profession, especially in primary care physicians who are usually the first port of call for the patient. Hypogonadism can significantly reduce the quality of life and has resulted in the loss of livelihood and separation of couples, leading to divorce. It is also important for doctors to recognize that testosterone is not just a sex hormone. There is an important research being published to demonstrate that testosterone may have key actions on metabolism, on the vasculature, and on brain function, in addition to its well-known effects on bone and body composition. This article has been used as an introduction for the need to develop sensitive and reliable assays for sex hormones and for symptoms and treatment of hypogonadism.

Kumar, Peeyush; Kumar, Nitish; Thakur, Devendra Singh; Patidar, Ajay

2010-01-01

139

[Erectile dysfunction: a sentinel symptom?].  

PubMed

Erectile dysfunction (ED) is a frequent disorder affecting the man's sexual and relational quality of life. French epidemiological studies estimate that the prevalence of ED is between 11% and 44% and prevalence surveys show a correlation between ED and age: the relative risk of erectile dysfunction increases by a factor of 2 to 4 between the ages of 40 and 70 years. Few patients consult their doctor and only a small proportion of them receive treatment and few doctors take the initiative to discuss the question of their patients' sex life. Doctors should now have a good understanding of erectile dysfunction and must be aware of the importance of detecting or at least investigating any erectile dysfunction, which can be the first symptom of an underlying disease such as cardiovascular disease, diabetes, depression, benign prostatic hyperplasia, prostate cancer, androgen deficiency or a drug-induced effect. Demonstration of erectile disorders therefore represents an excellent opportunity to conduct a general work-up, as more than one-third of patients with ED ignore their underlying health problem and management of ED is therefore an integral part of preventive medicine. PMID:15999593

Costa, Pierre; Grivel, Thierry; Giuliano, François; Pinton, Philippe; Amar, Edouard; Lemaire, Antoine

2005-04-01

140

Manic symptoms associated with quetiapine treatment  

Microsoft Academic Search

This case illustrates the induction of manic-like symptoms in a 26-year-old male patient with DSM-IV paranoid schizophrenia following treatment with quetiapine. The only drug he had received prior to quetiapine was risperidone which was occasionally taken in the previous 3 years. The manic symptoms remitted after quetiapine withdrawal.

Lefteris Lykouras; Panagiotis Oulis; John Hatzimanolis

2003-01-01

141

Bullying, depressive symptoms and suicidal thoughts  

Microsoft Academic Search

Bullies, victims and pupils neutral to bullyingwere compared on depressive symptoms and suicidal thoughts.The sample included 2,088 Norwegian boys and girls in grade 8. The results revealed that both bullies and victims had significantly higher mean scores than neutral pupils on both depressive symptoms and suicidal thoughts. Victims had a significantly higher mean score on depressive thoughts than the bullies.

Erling Roland

2002-01-01

142

Somatic Symptoms in Traumatized Children and Adolescents  

ERIC Educational Resources Information Center

Childhood exposure to trauma has been associated with increased rates of somatic symptoms (SS), which may contribute to diminished daily functioning. One hundred and sixty-one children residing at a residential treatment home who had experienced neglect and/or abuse were administered the Trauma Symptom Checklist for Children (TSCC), the…

Kugler, Brittany B.; Bloom, Marlene; Kaercher, Lauren B.; Truax, Tatyana V.; Storch, Eric A.

2012-01-01

143

Depressive symptoms in patients with chronic pain  

Microsoft Academic Search

Objective: To determine the nature of depressive symptoms in a sample of patients with chronic pain, and to examine the relationship between depressive symptoms and physical disability due to pain. Design, participants and setting: Cross-sectional study of 812 patients with complete datasets from a total of 2419 patients with pain who were referred to the Pain Management Research Institute at

Michael K Nicholas; Carissa M Coulston; Ali Asghari; Gin Singh Malhi

2009-01-01

144

Depressive Symptoms in African-American Women.  

ERIC Educational Resources Information Center

Examined the prevalence of depressive symptoms in an African American female college student sample (n=78) using the Minnesota Multiphasic Personality Inventory (MMPI2) and the Beck Depression Inventory (BDI). MMPI-2 was a more conservative scale than BDI in identifying depressive symptom levels. Discusses stress inoculation methods to assist…

Reed, Michael K.; And Others

1996-01-01

145

Dreams as a cause of symptoms  

Microsoft Academic Search

Discusses the mechanism and interpretation of dreams. Dreams are examined as the causal factors of symptoms. They may be the source of depression in some individuals and these symptoms may persist. The manifest content of dreams is a distortion of a repressed wish of the dreamer. M. Prince (see Journal of Abnormal Psychology, Vol 5, 139-195, PA: 52638) has referred

G. A. Waterman

1910-01-01

146

Evaluating Athletes Who Have Heart Symptoms.  

ERIC Educational Resources Information Center

Athletes with heart symptoms require, in addition to the regular evaluations everyone receives, testing during exercise. History taking should be carefully conducted to properly determine adverse heart conditions. Recommendations are provided for proper diagnosis and handling of athletes with heart symptoms. (GLR)

Cheitlin, Melvin D.

1993-01-01

147

Post-traumatic symptoms in abused children  

Microsoft Academic Search

A variety of symptoms have been described as sequelae of physical and sexual abuse in childhood. This review suggests that some of these symptoms can be understood as developmentally mediated manifestations of post-traumatic disorders. Like traumatized combat or concentration camp survivors, severely abused children develop anxiety, compulsive repetitions, sleep disturbances and depression, ego constriction, and disturbed expressions of anger. The

Jean Goodwin

1988-01-01

148

Self-blame and depressive symptoms  

Microsoft Academic Search

Investigated whether internal attributions for bad events are always associated with depression. The depressive symptoms of 86 female undergraduates correlated with blame directed at their own characters. In contrast, blame directed at their own behaviors correlated with lack of depressive symptoms. Behaviorally attributed bad events were seen as more controllable and their causes less stable and less global than were

Christopher Peterson; Stanley M. Schwartz; Martin E. Seligman

1981-01-01

149

Equol improves menopausal symptoms in Japanese women.  

PubMed

It has been well documented that the frequency of vasomotor menopausal symptoms, such as hot flashes and night sweats, of Japanese menopausal women is less than that of Western women. High intake of soy isoflavones in the traditional Japanese diet has been postulated as the possible explanation of the difference. Epidemiological studies have reported that the content of equol, which is a biologically active metabolite of the isoflavone, daidzein, is lower in the women who complain of severe vasomotor symptoms. To investigate the involvement of equol in the manifestation of menopausal symptoms, especially vasomotor symptoms, and the possible therapeutic role of a supplement containing equol (natural S-equol developed by Otsuka Pharmaceutical) on the menopausal symptoms of Japanese women, 3 randomized clinical trials were conducted. The studies indicated that a daily dose of 10 mg of natural S-equol improved menopausal symptoms. In the confirmation study, menopausal women who were equol nonproducers who consumed 10 mg/d of natural S-equol for 12 wk had significantly reduced severity and frequency of hot flashes as well as a significant reduction in the severity of neck or shoulder stiffness. The equol-ingesting group also showed trends of improvement in sweating and irritability and a significant improvement in the somatic category symptoms. Thus, it is concluded that the supplement containing natural S-equol, a novel soybean-derived functional component, has a promising role as an alternative remedy in the management of menopausal symptoms. PMID:20484552

Aso, Takeshi

2010-07-01

150

Signs and Symptoms of Celiac Disease  

MedlinePLUS

Do You Have Celiac Disease? Find Your Symptoms List of 261 The Celiac Support Association has an online application that will allow you ... See a listing of symptoms by affected system Celiac Disease occurs in: 3.9 -12.3% of ...

151

Alexithymia and Eating Disorder Symptoms in Adolescents  

Microsoft Academic Search

An increasing amount of evidence indicates an association between alexithymia and eating disorder symptoms. This possible association was evaluated in a non-clinical sample of late adolescents. Seven hundred and twenty nine adolescents completed the questionnaire and formed the final sample. Alexithymia was measured using the 20-item Toronto Alexithymia Scale and eating disorder symptoms were assessed using the SCOFF questionnaire. The

Max Karukivi; Lea Hautala; Jan Korpelainen; Kirsi-Maria Haapasalo-Pesu; Pirjo-Riitta Liuksila; Matti Joukamaa; Simo Saarijärvi

2010-01-01

152

Some Symptoms, Causes, and Remediations of Dyslexia.  

ERIC Educational Resources Information Center

A literature review was conducted to determine the meaning, symptoms, causes, and treatment of dyslexia. The review revealed that dyslexia simply means "distorted words," and is the inability to read either phonetically or visually. Among the symptoms of dyslexia disclosed by the review are motion sickness, retardation in reading of from 6 months…

Groff, Charlotte V.

153

Illness Representations and Matching Labels With Symptoms  

Microsoft Academic Search

Three studies are reported that show that health-relevant information (e.g., blood pressure [BP] or symptoms) initiates an active cognitive search process that results in the construction of an illness representation. Study 1 showed that informing subjects that their BP was elevated affected two attributes of illness representation: identity (label and symptoms), and time line or expected chronology of the health

Linda J. Baumann; Linda D. Cameron; Rick S. Zimmerman; Howard Leventhal

1989-01-01

154

Prevalence of gastro-oesophageal reflux disease symptoms and reflux-associated respiratory symptoms in asthma  

PubMed Central

Background Gastro-oesophageal reflux disease (GORD) symptoms are common in asthma and have been extensively studied, but less so in the Asian continent. Reflux-associated respiratory symptoms (RARS) have, in contrast, been little-studied globally. We report the prevalence of GORD symptoms and RARS in adult asthmatics, and their association with asthma severity and medication use. Methods A cross-sectional analytical study. A validated interviewer-administered GORD scale was used to assess frequency and severity of seven GORD symptoms. Subjects were consecutive asthmatics attending medical clinics. Controls were matched subjects without respiratory symptoms. Results The mean (SD) composite GORD symptom score of asthmatics was significantly higher than controls (21.8 (17.2) versus 12.0 (7.6); P < 0.001) as was frequency of each symptom and RARS. Prevalence of GORD symptoms in asthmatics was 59.4% (95% CI, 59.1%-59.6%) versus 28.5% in controls (95% CI, 29.0% - 29.4%). 36% of asthmatics experienced respiratory symptoms in association with both typical and atypical GORD symptoms, compared to 10% of controls (P < 0.001). An asthmatic had a 3.5 times higher risk of experiencing a GORD symptom after adjusting for confounders (OR 3.5; 95% CI 2.5-5.3). Severity of asthma had a strong dose-response relationship with GORD symptoms. Asthma medication use did not significantly influence the presence of GORD symptoms. Conclusions GORD symptoms and RARS were more prevalent in a cohort of Sri Lankan adult asthmatics compared to non-asthmatics. Increased prevalence of RARS is associated with both typical and atypical symptoms of GORD. Asthma disease and its severity, but not asthma medication, appear to influence presence of GORD symptoms.

2010-01-01

155

Ser 524 is a phosphorylation site in MUTYH and Ser 524 mutations alter 8-oxoguanine (OG):A mismatch recognition  

PubMed Central

MUTYH-associated polyposis (MAP) is a colorectal cancer predisposition syndrome that is caused by inherited biallelic mutations in the base excision repair (BER) gene, MUTYH. MUTYH is a DNA glycosylase that removes adenine (A) misinserted opposite 8-oxo-7,8-dihydro-2'-deoxyguanosine (OG). In this work, wild type (WT) MUTYH overexpressed using a baculovirus-driven insect cell expression system (BEVS) provided significantly higher levels of enzyme compared to bacterial overexpression. The isolated MUTYH enzyme was analyzed for potential post-translational modifications using mass spectrometry. An in vivo phosphorylation site was validated at Serine 524, which is located in the C-terminal OG recognition domain within the proliferating cell nuclear antigen (PCNA) binding region. Characterization of the phosphomimetic (S524D) and phosphoablating (S524A) mutants together with the observation that Ser 524 can be phosphorylated suggest that this residue may play an important regulatory role in vivo by altering stability and OG:A mismatch affinity.

Kundu, Sucharita; Brinkmeyer, Megan K.; Eigenheer, Richard A.; David, Sheila S.

2010-01-01

156

Methodological Issues in Negative Symptom Trials  

PubMed Central

Individuals from academia, the pharmaceutical industry, and the US Food and Drug Administration used a workshop format to discuss important methodological issues in the design of trials of pharmacological agents for improving negative symptoms in schizophrenia. The issues addressed included the need for a coprimary functional measure for registration trials; the characteristics of individuals who should enter negative symptom trials; the optimal duration for a proof-of-concept or registration trial; the optimal design of a study of a broad-spectrum agent that treats both positive and negative symptoms or a co-medication that is added to an antipsychotic; the relative strengths and weaknesses of available instruments for measuring negative symptoms; the definition of clinically meaningful improvement for these trials; and whether drugs can be approved for a subdomain of negative symptoms.

Marder, Stephen R.; Daniel, David G.; Alphs, Larry; Awad, A. George; Keefe, Richard S. E.

2011-01-01

157

Behavioral inhibition and PTSD symptoms in veterans  

PubMed Central

Behavioral inhibition (BI), a temperamental bias to respond to novel stimuli with avoidance behaviors, is a risk factor for posttraumatic stress disorder (PTSD). It is unclear whether BI accounts for additional variance in PTSD symptom severity beyond that accounted for by general anxiety. Here, 109 veterans (mean age 50.4 years, 9.2% female) provided self-assessment of PTSD symptoms, state and trait anxiety, combat exposure, and current (adult) and retrospective (childhood) BI. Adult BI was correlated with anxiety and PTSD symptom severity, especially cluster C (avoidance) symptoms, but not with combat exposure. A regression model including adult BI, state and trait anxiety, and combat exposure was able to correctly classify over 80% of participants according to presence or absence of severe PTSD symptoms. Because avoidance behaviors are a core component of PTSD, self-assessments of BI may be an important tool in understanding PTSD and potentially assessing vulnerability to the disorder.

Myers, Catherine E.; VanMeenen, Kirsten M.; Servatius, Richard J.

2012-01-01

158

Parent Ratings of ADHD Symptoms: Differential Symptom Functioning across Malaysian Malay and Chinese Children  

ERIC Educational Resources Information Center

This study examined differential symptom functioning (DSF) in ADHD symptoms across Malay and Chinese children in Malaysia. Malay (N = 571) and Chinese (N = 254) parents completed the Disruptive Behavior Rating Scale, which lists the DSM-IV ADHD symptoms. DSF was examined using the multiple indicators multiple causes (MIMIC) structural equation…

Gomez, Rapson; Vance, Alasdair

2008-01-01

159

Deployment-Related TBI, Persistent Postconcussive Symptoms, PTSD, and Depression in OEF\\/OIF Veterans  

Microsoft Academic Search

Objective: A substantial proportion of the more than 2 million service members who have served in Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) have experienced a traumatic brain injury (TBI). Understanding the long-term impact of TBI is complicated by the nonspecific nature of postconcussive symptoms (PCSs) and the high rates of co-occurrence among TBI, posttraumatic stress disorder (PTSD),

Sandra B. Morissette; Matthew Woodward; Nathan A. Kimbrel; Eric C. Meyer; Marc I. Kruse; Sara Dolan; Suzy Bird Gulliver

2011-01-01

160

Menopausal hormone therapy and menopausal symptoms.  

PubMed

A majority of women will experience bothersome symptoms related to declining and/or fluctuating levels of estrogen during their menopausal transition. Vasomotor symptoms, vaginal dryness, poor sleep, and depressed mood have all been found to worsen during the menopausal transition. While vasomotor symptoms gradually improve after menopause, the time course can be many years. Vaginal dryness does not improve without treatment, while the long-term course of sleep and mood deterioration is not clearly defined at this time. A small minority of women have vasomotor symptoms that persist throughout the remainder of their lives. These common menopausal symptoms all improve with estrogen treatment. Over the last 10 years, we have witnessed a dramatic reduction in enthusiasm for menopausal hormone therapy, despite its high efficacy relative to other treatments. We have also seen the emergence of sound, evidence-based clinical trials of non-hormonal alternatives that can control the common menopausal symptoms. Understanding the natural history of menopausal symptoms, and the risks and benefits of both hormonal and non-hormonal alternatives, helps the clinician individualize management plans to improve quality of life. PMID:24613533

Al-Safi, Zain A; Santoro, Nanette

2014-04-01

161

Somatic Symptom Reporting in Women and Men  

PubMed Central

Women report more intense, more numerous, and more frequent bodily symptoms than men. This difference appears in samples of medical patients and in community samples, whether or not gynecologic and reproductive symptoms are excluded, and whether all bodily symptoms or only those which are medically unexplained are examined. More limited, but suggestive, literature on experimental pain, symptom reporting in childhood, and pain thresholds in animals are compatible with these findings in adults. A number of contributory factors have been implicated, supported by varying degrees of evidence. These include innate differences in somatic and visceral perception; differences in symptom labeling, description, and reporting; the socialization process, which leads to differences in the readiness to acknowledge and disclose discomfort; a sex differential in the incidence of abuse and violence; sex differences in the prevalence of anxiety and depressive disorders; and gender bias in research and in clinical practice. General internists need to keep these factors in mind in obtaining the clinical history, understanding the meaning and significance that symptoms hold for each patient, and providing symptom relief.

Barsky, Arthur J; Peekna, Heli M; Borus, Jonathan F

2001-01-01

162

Fatigue and depressive symptoms in older people.  

PubMed

Fatigue is considered an important indicator of aging-related declines in health and functional abilities. Previous studies have indicated strong associations between fatigue and depressive symptoms among younger populations and in patient groups with specific diseases. However, it is not known how different measures of fatigue are associated with depressive symptoms among general older populations. The purpose of this study is to describe the prevalence of depressive symptoms among community-dwelling older adults reporting mobility-related or general feelings fatigue. The study population consisted of 75-year-old community-living individuals (n = 561). Both, mobility-related and general fatigue, were associated in a stepwise relationship with depressive symptoms: a higher level of fatigue was related to higher level of depressive symptoms. Especially major general fatigue was strongly associated with high level of depressive symptoms. It is important for professionals of the field to be aware of the associations between different measures of fatigue and depressive symptoms. PMID:24781969

Mänty, Minna; Rantanen, Taina; Era, Pertti; Avlund, Kirsten

2014-06-01

163

Beyond Intuition: Patient Fever Symptom Experience  

PubMed Central

Context Fever is an important sign of inflammation recognized by health care practitioners and family caregivers. However, few empirical data obtained directly from patients exist to support many of the long-standing assumptions about the symptoms of fever. Many of the literature-cited symptoms, including chills, diaphoresis, and malaise, have limited scientific bases, yet they often represent a major justification for antipyretic administration. Objectives To describe the patient experience of fever symptoms for the preliminary development of a fever assessment questionnaire. Methods Qualitative interviews were conducted with 28 inpatients, the majority (86%) with cancer diagnoses, who had a recorded temperature of ?38°C within approximately 12 hours before the interview. A semi-structured interview guide was used to elicit patient fever experiences. Thematic analyses were conducted by three independent research team members, and the data were verified through two rounds of consensus building. Results Eleven themes emerged. The participants reported experiences of feeling cold, weakness, warmth, sweating, nonspecific bodily sensations, gastrointestinal symptoms, headaches, emotional changes, achiness, respiratory symptoms, and vivid dreams/hallucinations. Conclusion Our data not only confirm long-standing symptoms of fever but also suggest new symptoms and a level of variability and complexity not captured by the existing fever literature. Greater knowledge of patients’ fever experiences will guide more accurate assessment of symptoms associated with fever and the impact of antipyretic treatments on patient symptoms in this common condition. Results from this study are contributing to the content validity of a future instrument that will evaluate patient outcomes related to fever interventions.

Ames, Nancy J.; Peng, Claudia; Powers, John H.; Leidy, Nancy Kline; Miller-Davis, Claiborne; Rosenberg, Alice; VanRaden, Mark; Wallen, Gwenyth R.

2013-01-01

164

Association of ventilation system type with SBS symptoms in office workers  

SciTech Connect

This paper provides a review and synthesis of current knowledge about the associations of ventilation system types in office buildings with sick building syndrome symptoms and discusses potential explanations for the associations. Relative to natural ventilation, air conditioning, with or without humidification, was consistently associated with a statistically significant increase in the prevalence of one or more SBS symptoms. Prevalences were typically higher by approximately 30% to 200% in the air conditioned buildings. In two of three assessments from a single study, symptom prevalences were also significantly higher in air conditioned buildings than in buildings with simple mechanical ventilation and no humidification. In approximately half of assessments, SBS symptom prevalences were significantly higher in buildings with simple mechanical ventilation than in buildings with natural ventilation. Insufficient information was available for conclusions about the potential increased risk of SBS symptoms with humidification. The statistically significant associations of mechanical ventilation and air conditioning with SBS symptoms are much more frequent than expected from chance and also not likely to be a consequence of confounding by several potential personal, job, or building related confounders. The reasons for the increases in symptom prevalences with mechanical ventilation and particularly with air conditioning remain unclear. Multiple deficiencies in HVAC system design, construction, operation, or maintenance, including some which cause pollutant emissions from HVAC systems, may contribute to the increases in symptom prevalences.

Seppanen, Olli; Fisk, William J.

2001-02-07

165

Psychiatric symptoms moderate the effects of mental illness self-management in a randomized controlled trial.  

PubMed

Depression has been shown to moderate the effects of physical illness self-management (ISM) programs. We attempted to replicate these findings for a mental ISM intervention. Outpatients with serious mental illness (N = 428) from eight Tennessee communities were randomly assigned to receive a peer-led self-management intervention called Building Recovery of Individual Dreams and Goals Through Education and Support or services as usual. Psychiatric symptoms were assessed with the Brief Symptom Inventory; the outcome of personal empowerment was measured by the Empowerment Scale. Intent-to-treat analysis using mixed-effects random regression found significant interaction effects between study condition and three moderating symptom profiles. Empowerment was greater for the intervention participants with high levels of depressive symptoms, anxiety symptoms, and general symptom distress than for the experimental participants with low symptom levels and the control subjects with high or low levels of symptoms. These results shed light on how mental ISM programs operate and ways these can be improved. PMID:24566504

Steigman, Pamela J; Pickett, Susan A; Diehl, Sita M; Fox, Anthony; Grey, Dennis D; Shipley, Patricia; Cook, Judith A

2014-03-01

166

Worry and obsessional symptoms: a correlational analysis.  

PubMed

Several studies have suggested that worry and obsessional symptoms are systematically associated. In the present study, the relationship between worry and obsessional symptoms was confirmed. Measures included a worry content measure, a worry visual analogue scale, a modification of the everyday checking behaviours scale, and the MOCI. Worry was found to be more consistently associated with checking and doubting, than washing and slowness. It is suggested that worry and obsessional symptoms both occur in response to stress. In addition, it is suggested that worry and checking are functionally similar, and Generalised Anxiety Disorder may represent a 'cognitive' variant of obsessional checking. PMID:1567338

Tallis, F; de Silva, P

1992-03-01

167

Factitious disorder presenting with acute cardiovascular symptoms.  

PubMed

A 23-year-old female student exhibited all the characteristics of chronic factitious disorder with physical symptoms (Munchhausen's syndrome): deliberate simulation of illness, peregrination, fantastic pseudology and dramatic circumstances on admittance. The patient induced impressive blood pressure peaks by the Valsalva manoeuvre. She also simulated arrhythmias, seizures and unconsciousness. Her symptoms had previously led to comprehensive cardiological, neurological and endocrinological evaluations and treatment in at least three different countries in two continents. A literature survey suggests that facitious cardiovascular symptoms have become more frequent during recent decades. PMID:7989905

Ludwigs, U; Ruiz, H; Isaksson, H; Matell, G

1994-12-01

168

Symptoms of depression in ICU physicians  

PubMed Central

Background Work and family are the two domains from which most adults develop satisfaction in life. They also are responsible for stressful experiences. There is a perception in the community that work is increasingly the source of much of our stress and distress. Depressive symptoms may be related to repeated stressful experiences. Intensive care unit (ICU) physicians are exposed to major stressors. However, the existence of depressive symptoms in these doctors has been poorly studied. This study was designed to evaluate the prevalence and associated risk factors of depressive symptoms in junior and senior ICU physicians. Method A one-day national survey was conducted in adult intensive care units (ICU) in French public hospitals. Symptoms of depression were assessed using the Centers of Epidemiologic Studies Depression Scale (CES-D). Results A total of 189 ICUs participated, and 901 surveys were returned (75.8% response rate). Symptoms of depression were found in 23.8% of the respondents using the CES-D scale. Fifty-eight percent of these intensivists presenting symptoms of depression wished to leave their job compared with only 33% of those who did not exhibit signs of depression as assessed by the CES-D scale (p?symptoms. Workload (long interval since the last nonworking weekend, absence of relief of service until the next working day after a night shift) and impaired relationships with other intensivists were independently associated with the presence of depressive symptoms. A high level of burnout also was related to the presence of depressive symptoms. In contrast, no demographic factors regarding ICU physicians and no factor related to the severity of illness of patients were retained by the model. The quality of relationships with other physicians (from other departments) was associated with the absence of depressive symptoms (protective effect). Conclusions Approximately one of four intensivists presented symptoms of depression. The next step could be to test whether organization modification is associated with less depressive symptoms and less desire to leave the job.

2012-01-01

169

OG1: A Natural Reference Material for Quantifying SIMS Instrumental Mass Fractionation of Pb Isotopes During Zircon Dating  

NASA Astrophysics Data System (ADS)

Over the last 20 years, it has become common practice to treat SIMS measurements of 207Pb/206Pb in zircon as unfractionated. Consequently, uncertainties associated with composite 207Pb/206Pb values are often limited only by population statistics of the weighted mean, and citation of 95% confidence limits of 1‰ (or less) on Meso- to Paleoarchean mean ages is increasingly commonplace. In such cases, the presence of undiagnosed SIMS instrumental mass fractionation of 207Pb/206Pb of similar magnitude (1-2‰) could have serious ramifications for the accuracy of the measured age: in extreme cases, the ‘true’ 207Pb/206Pb may not even lie within the artificially narrow 95% confidence interval of the measured value. This possibility has important implications for high-precision zircon geochronology via SIMS, and the correlation of Precambrian events. Our previous work has characterized (via ID-TIMS) a Paleoarchean igneous zircon reference material (‘OG1’). Its reference 207Pb/206Pb is 0.29907 ± 0.00011 (3465.4 ± 0.6 Ma) for natural (air-abraded) zircon, and 0.29939 ± 0.00012 (3467.1 ± 0.6 Ma) for zircon annealed and chemically abraded using the Mattinson technique. The corresponding reference 206Pb/238U ages are 3440.7 ± 3.2 Ma and 3463.3 ± 3.6 Ma respectively. We have used OG1 to demonstrate long-term inter-session reproducibility of mean 207Pb/206Pb for one SIMS instrument (Geoscience Australia’s SHRIMP-IIe), where 36 of 37 session ?OG1 values (?OG1 = 1000 × [M / R - 1], where M and R are the Measured [SIMS] and Reference [‘natural’ ID-TIMS] 207Pb/206Pb) between -0.8 ± 1.4‰ and +2.5 ± 1.5‰ yielded a weighted mean ?OG1 of +0.90 ± 0.25‰ (95% confidence, MSWD = 1.3). However, 10 sessions on other SHRIMPs indicated inter-instrument dispersal in mean 207Pb/206Pb well beyond uncertainties, with session ?OG1 spanning the range +3.9 ± 1.7‰ to -2.8 ± 1.0‰. The causes of this variability in ?OG1 remain unconstrained at present. In the absence of any discernible Pb-hydrides (based on measurements at mass 209 on Pb-feldspar), the tendency of the Geoscience Australia SHRIMP-IIe towards positive ?OG1 values (indicating relative enrichment in 207Pb, and opposing the pattern expected for secondary ionization) is the subject of continuing research. The common presence of narrow, U-rich rims on natural OG1 grains means that ion probe spots are typically situated away from the edges of meridionally-sectioned crystals, so one possibility is that the material typically sputtered during SIMS analysis bears a closer isotopic resemblance to chemically-abraded zircon than ‘bulk’ natural zircon (as the latter retains slight discordance even after air abrasion). Current work involves chemical abrasion of a large quantity of OG1 for SIMS analysis, to assess whether removing discordant material will assist in resolving any ‘true’ intra-session instrumental component in ?OG1 from any systematic inter-session offset arising from the selection of an inappropriate reference value.

Bodorkos, S.; Stern, R. A.; Kamo, S.; Corfu, F.; Hickman, A. H.

2009-12-01

170

Depressive symptoms amongst asthmatic children's caregivers.  

PubMed

We wanted to find out, whether the number of depressive symptoms is higher amongst asthmatic children's caregivers, compared to international data, to the Hungarian population average, and to parents of children with chronic renal disease. Are these depressive symptoms connected to the children's psychological status, asthma severity or current asthma symptoms? One-hundred and eight, 7- to 17-yr-old asthmatic children were enrolled, who have been treated at the Semmelweis University, First Department of Pediatrics. Children were suffering from asthma for at least 1 yr, with a median of 8 yr (1-16 yr), they started to develop asthmatic symptoms between the age of 0.5-14 yr (median: 3 yr). We also identified 27 children with chronic renal diseases and their caregivers, who functioned as a control group. Children were asked to complete the Hungarian-validated versions of the Child Depression Inventory, the Spielberger State Anxiety Inventory for Children and the Juniper Pediatric Asthma Quality of Life Questionnaire. Asthma severity and current symptoms were also documented, 56% had no symptoms on the preceding week. Caregivers were asked to complete the Hungarian versions of the Beck Depression Inventory (BDI) short form, the Spielberger Anxiety Inventory and the Juniper Pediatric Asthma Caregivers' Quality of Life Questionnaire. Caregivers of asthmatic children had significantly more depressive symptoms (7.73 +/- 6.69 s.d.) than the age-specific normal population (p < 0.01). Caregivers of renal patients also experience more depressive symptoms (9.61 +/- 7.43 s.d.) than their healthy peers, but difference between the two chronic diseases' group did not prove to be significant. Asthmatic children's caregivers who scored more points on the BDI than the population average suffer from more anxiety symptoms, but their quality of life is not worse than the caregivers' with less depressive points. Depressive symptoms were neither connected to the children's psychological and asthmatic symptoms nor quality of life. Amongst caregivers of asthmatic children, at least mild depressive symptoms were represented amongst 39% of men and 33% of women. Gender difference was not significant, despite observations in the normal Hungarian population. Amongst caregivers of renal patients, depressive symptoms were represented in 14% of men and 50% of women. Gender difference was significant. (p = 0.05). Significant difference was observed between male asthmatic and renal caregivers, albeit difference was not significant between the female groups. No difference was found in depressive symptoms according to caregivers' level of education. Caregivers of children with asthma have more depressive symptoms than the average Hungarian population, but their results do not differ from caregivers taking care of children with chronic renal diseases. Caregivers of asthmatic children having at least mild depressive symptoms tend to have higher anxiety symptoms as well. Up to date, childhood chronic disease management and long-term care should also focus on parental psychology, mainly on depression and anxiety, as prevalence is higher than in the average population. PMID:19744221

Szabó, Alexandra; Mezei, Györgyi; Kovári, Eva; Cserháti, Endre

2010-06-01

171

Home Care Nursing Improves Cancer Symptom Management  

Cancer.gov

Home care nursing (HCN) improves the management of symptoms in breast and colorectal cancer patients who take the oral chemotherapy drug capecitabine, according to a study published online November 16, 2009, in the Journal of Clinical Oncology.

172

Men with Eating Disorders Often Ignore Symptoms  

MedlinePLUS

... on this page, please enable JavaScript. Men With Eating Disorders Often Ignore Symptoms British study finds that too many males associate anorexia, bulimia as only a woman's issue (*this news item ...

173

Symptoms, Diagnosis and Treatment for Pulmonary Fibrosis  

MedlinePLUS

... Diagnosis and Treatment What are the Symptoms of Pulmonary Fibrosis? Shortness of breath, particularly during exercise Dry, hacking ... tips of the fingers or toes) How is Pulmonary Fibrosis Detected? Your doctor will do a physical exam. ...

174

HIV/AIDS Basics - Signs & Symptoms  

MedlinePLUS Videos and Cool Tools

English - HIV/AIDS-Signs and Symptoms Video Audio Handout Terms of Use Close Window This information made possible with support ... National Library of Medicine For more information on HIV/AIDS see AIDS.gov

175

Restless Legs Syndrome -- Causes and Symptoms  

MedlinePLUS

Restless Legs Syndrome - Causes & Symptoms Causes What causes of restless legs syndrome varies from person to person. In some cases ... with brain cell communication that can lead to restless legs syndrome. If you think you have restless legs syndrome ...

176

Symptoms and Complications of Flu (Influenza)  

MedlinePLUS

... JavaScript on. Read more information on enabling JavaScript. Flu (Influenza) Skip Content Marketing Share this: Main Content ... Open All Influenza Symptoms People who have the flu often experience Fever Feeling feverish/chills Cough Sore ...

177

Symptoms of Vaginal and Vulvar Cancers  

MedlinePLUS

... Announcements Radio Public Service Announcements Print Materials Campaign Research Doctors Who Use Social Media Poster Presentation Buttons and Badges Related Resources Gynecologic Cancer Symptoms Diary [PDF-503KB] Vaginal and Vulvar Cancer fact sheet [ ...

178

Teens Who Intimidate Adults: Understanding Symptom Estrangement  

ERIC Educational Resources Information Center

This story gives a brief overview of the possibilities and opportunities of the Symptom Estrangement Reclaiming Intervention. It is the history of a three-year effort with a child caught in this self-defeating pattern of behaviour.

De Moor, Gerrit

2010-01-01

179

Methods of symptom evaluation and their impact on peripheral artery disease (PAD) symptom prevalence: A review  

PubMed Central

Peripheral artery disease (PAD) is a common progressive atherosclerotic occlusive disease that causes insufficient blood flow to the lower extremities. The symptom that health care professionals most often associate with PAD is claudication. However, patient reporting of claudication is highly variable. A structured literature review was conducted to evaluate how PAD symptoms are identified, defined, and categorized. This review focuses on the development and performance characteristics of PAD symptom questionnaires and the identification of a spectrum of leg symptoms beyond classic claudication. Additionally, potential confounders of PAD symptom report and strategies for a more comprehensive assessment of PAD symptoms are discussed. Overall, there is a lack of consistency in the utilization of PAD claudication questionnaires which impacts PAD symptom reporting and categorization. Based on this review, atypical symptoms are commonly reported, but poorly understood. Additional research is needed to gain a better understanding of the presentation of atypical symptoms, as well as the role of age, gender, race, and comorbid conditions on the symptom experience of patients with PAD.

Schorr, Erica N.; Treat-Jacobson, Diane

2013-01-01

180

Posttraumatic stress symptoms after childhood cancer  

Microsoft Academic Search

The posttraumatic stress model has recently been applied to understand the impact of life-threatening illness in adults and in children. From 1991 to 2001, 20 studies have reported posttraumatic stress symptoms and\\/or posttraumatic stress disorder (PTSD) in childhood cancer survivors and\\/or their parents. A review of these studies is proposed. Prevalence of posttraumatic stress symptoms and\\/or PTSD in children and

Olivier Taïeb; MarieRose Moro; Thierry Baubet; Anne Revah-Lévy; Martine F. Flament

2003-01-01

181

Depressive symptoms during the menopausal transition  

PubMed Central

Background The influence of menopausal status on depressive symptoms is unclear in diverse ethnic groups. This study examined the longitudinal relationship between changes in menopausal status and the risk of clinically relevant depressive symptoms and whether the relationship differed according to initial depressive symptom level. Methods 3302 African American, Chinese, Hispanic, Japanese, and White women, aged 42-52 years at entry into the Study of Women’s Health Across the Nation (SWAN), a community-based, multisite longitudinal observational study, were evaluated annually from 1995 through 2002. Random effects multiple logistic regression analyses were used to determine the relationship between menopausal status and prevalence of low and high depressive symptom scores (CES-D <16 or ? 16) over 5 years Results At baseline, 23% of the sample had elevated CES-D scores. A woman was more likely to report CES-D ?16 when she was early peri-, late peri-, postmenopausal or currently/ formerly using hormone therapy (HT), relative to when she was premenopausal (OR range 1.30 to 1.71). Effects were somewhat stronger for women with low CES-D scores at baseline. Health and psychosocial factors increased the odds of having a high CES-D and in some cases, were more important than menopausal status. Limitations We used a measure of current depressive symptoms rather than a diagnosis of clinical depression. Thus, we can only make conclusions about symptoms current at annual assessments. Conclusion Most midlife women do not experience high depressive symptoms. Those that do are more likely to experience high depressive symptom levels when perimenopausal or postmenopausal than when premenopausal, independent of factors such as difficulty paying for basics, negative attitudes, poor perceived health, and stressful events.

Bromberger, Joyce T.; Matthews, Karen A; Schott, Laura L.; Brockwell, Sarah; Avis, Nancy E.; Kravitz, Howard M.; Everson-Rose, Susan A.; Gold, Ellen B.; Sowers, MaryFran; Randolph, John F.

2007-01-01

182

Trauma Symptoms of Former Intimate Stalking Victims  

Microsoft Academic Search

One-hundred-eighty-seven female victims stalked by former intimate partners were interviewed about their victimization experiences. To identify psychological symptoms experienced by the victims, Briere and Runtz's (1989) Trauma Symptom Checklist (TSC-33) was utilized in the interview. Individual items were combined to form five distinct scales as developed and validated by Briere and Runtz (1989). Findings reveal that the highest mean scores

Mary P. Brewster

2002-01-01

183

Symptom attribution after a plane crash: comparison between self-reported symptoms and GP records.  

PubMed Central

BACKGROUND: On 4 October 1992, an El Al Boeing 747-F cargo aeroplane crashed on two apartment buildings in Amsterdam. Thirty-nine residents on the ground and the four crew members of the plane died. In the years after, a gradually increasing number of people attributed physical signs and symptoms to their presence at the disaster scene. AIM: To investigate the consistency between patients' symptoms attributed to the crash and GPs' diagnoses and perception of the association with the crash. DESIGN OF STUDY: Comparison between self-reported symptoms to a call centre and GPs' medical records on onset and type of symptoms, diagnoses, and GPs' perception of association with the disaster, assessed by questionnaire. SETTING: Consenting patients (n = 621) contacting the call centre and their GPs. METHOD: Patients were interviewed by the call centre staff and interview data were recorded on a database. Questionnaires were sent to the consenting patients' GPs, requesting their opinions on whether or not their patients' symptoms were attributable to the effects of disaster. Baseline differences and differences in reported symptoms between interviewed patients and their GP records were tested using the chi2 test. RESULTS: The 553 responders reported on average 4.3 symptoms to the call centre. The majority of these symptoms (74%) were reported to the GP. Of the ten most commonly reported symptoms, fatigue, skin complaints, feeling anxious or nervous, dyspnoea, and backache featured in 80% of symptoms reported to the GP. One out of four symptoms was either reported to the GP before the disaster took place, or six or more years after (1998/1999, during a period of much media attention). Depression (7%), post-traumatic stress disorder (PTSD) (5%) and eczema (5%) were most frequently diagnosed by GPs. They related 6% of all reported symptoms to the disaster. CONCLUSIONS: Most of the symptoms attributed to a disaster by patients have been reported to their GP, who related only a small proportion of these to the disaster.

Donker, G A; Yzermans, C J; Spreeuwenberg, P; van der Zee, J

2002-01-01

184

Testing the "PRESTo" early warning algorithm with OGS, ARSO and ZAMG seismic data: first results  

NASA Astrophysics Data System (ADS)

Since 2002 the OGS (Istituto Nazionale di Oceanografia e di Geofisica Sperimentale) in Udine (Italy), the Agencija Republike Slovenije za Okolje (ARSO) in Ljubljana (Slovenia) and the Zentralanstalt für Meteorologie und Geodynamik (ZAMG) in Vienna (Austria) are collecting, analyzing, archiving and exchanging seismic data in real time. The data exchange has proved to be effective and very useful in case of seismic events near the borders between Italy, Austria and Slovenia, where geographical distribution of the single national networks can not assure reliable location of the events outside or at the margin of the single networks, while the usage of common data from the integrated networks improves considerably the overall reliability of real time seismic monitoring of the area. In order to extend the seismic monitoring in North-eastern Italy, Slovenia and Southern Austria towards Earthquake Early Warning applications, at the end of 2013 OGS, ARSO and ZAMG teamed with AMRA-Università di Napoli in Italy to test the reliability of the Probabilistic and Evolutionary early warning SysTem (PRESTo) algorithm with their data: first test results will be illustrated.

Elia, Luca; Gosar, Andrej; Lenhardt, Wolfgang; Mucciarelli, Marco; Pesaresi, Damiano; Picozzi, Matteo; Zivcic, Mladen; Zollo, Aldo

2014-05-01

185

Tackling Negative Symptoms of Schizophrenia with Memantine  

PubMed Central

We present a case of a 52-year-old male patient suffering from chronic schizophrenia stabilized on risperidone long-acting injection (37,5?mg/2 weeks) and biperiden 4?mg/day. Residual symptoms are affective flattening, alogia, avolition, and asociality. Memantine 10?mg/day was added. After 1.5 months, the patient spontaneously referred to “feel better being in company of my relatives.” The following scales have been completed: the Scale for the Assessment of Negative Symptoms (96), the Scale for the Assessment of Positive Symptoms (3), the Mini Mental Scale Examination (26), and the Calgary Depression for Schizophrenia Scale (2). Memantine was increased to 20?mg/day and biperiden was decreased to 2?mg/day. Two months later, apathy and asociality considerably improved and affective flattening, alogia, and attention slightly got better (SANS 76, SAPS 1, MMSE 26, and CDSS 1). After two more months, the improvement continued in the same domains (SANS: 70, SAPS: 1 MMSE: 27, and CDSS: 1). Positive symptoms remained in full remission. It has been hypothesized that one of the causes of schizophrenia is glutamate excitotoxicity. Memantine, a glutamate receptor antagonist, could possibly ameliorate schizophrenia symptoms, the negative ones among them, used as add-on therapy to atypical antipsychotics. Memantine could be of potential help in schizophrenia patients with severe residual negative symptoms.

2014-01-01

186

Computerized Measurement of Negative Symptoms in Schizophrenia  

PubMed Central

Accurate measurement of negative symptoms is crucial for understanding and treating schizophrenia. However, current measurement strategies are reliant on subjective symptom rating scales which often have psychometric and practical limitations. Computerized analysis of patients’ speech offers a sophisticated and objective means of evaluating negative symptoms. The present study examined the feasibility and validity of using widely-available acoustic and lexical-analytic software to measure flat affect, alogia and anhedonia (via positive emotion). These measures were examined in their relationships to clinically-rated negative symptoms and social functioning. Natural speech samples were collected and analyzed for 14 patients with clinically-rated flat affect, 46 patients without flat affect and 19 healthy controls. The computer-based inflection and speech rate measures significantly discriminated patients with flat affect from controls, and the computer-based measure of alogia and negative emotion significantly discriminated the flat and non-flat patients. Both the computer and clinical measures of positive emotion/anhedonia corresponded to functioning impairments. The computerized method of assessing negative symptoms offered a number of advantages over the symptom scale-based approach.

Cohen, Alex S.; Alpert, Murray; Nienow, Tasha M.; Dinzeo, Thomas J.; Docherty, Nancy M.

2008-01-01

187

Neuropsychiatric symptoms three years after subthalamic DBS in PD patients  

Microsoft Academic Search

Objective\\u000a   To evaluate neuropsychiatric symptoms in PD patients submitted to bilateral deep brain stimulation of the subthalamic nucleus\\u000a (DBS-STN) by comparison with a control group of PD patients not treated with DBS.\\u000a \\u000a \\u000a \\u000a \\u000a Methods\\u000a   25 consecutive PD patients bilaterally implanted for DBS of STN (DBS group) were compared to a control group of 25 not operated\\u000a PD patients (CT group) for

Lorys Castelli; Maurizio Zibetti; Laura Rizzi; Marcella Caglio; Michele Lanotte; Leonardo Lopiano

2008-01-01

188

SalB inactivation modulates culture supernatant exoproteins and affects autolysis and viability in Enterococcus faecalis OG1RF.  

PubMed

The culture supernatant fraction of an Enterococcus faecalis gelE mutant of strain OG1RF contained elevated levels of the secreted antigen SalB. Using differential fluorescence gel electrophoresis (DIGE) the salB mutant was shown to possess a unique complement of exoproteins. Differentially abundant exoproteins were identified using matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry. Stress-related proteins including DnaK, Dps family protein, SOD, and NADH peroxidase were present in greater quantity in the OG1RF salB mutant culture supernatant. Moreover, several proteins involved in cell wall synthesis and cell division, including d-Ala-d-Lac ligase and EzrA, were present in reduced quantity in OG1RF salB relative to the parent strain. The salB mutant displayed reduced viability and anomalous cell division, and these phenotypes were exacerbated in a gelE salB double mutant. An epistatic relationship between gelE and salB was not identified with respect to increased autolysis and cell morphological changes observed in the salB mutant. SalB was purified as a six-histidine-tagged protein to investigate peptidoglycan hydrolytic activity; however, activity was not evident. High-pressure liquid chromatography (HPLC) analysis of reduced muropeptides from peptidoglycan digested with mutanolysin revealed that the salB mutant and OG1RF were indistinguishable. PMID:22563054

Shankar, Jayendra; Walker, Rachel G; Wilkinson, Mark C; Ward, Deborah; Horsburgh, Malcolm J

2012-07-01

189

Comparison of concussive symptoms, cognitive performance, and psychological symptoms between acute blast-versus nonblast-induced mild traumatic brain injury.  

PubMed

Blast-related head injuries are one of the most prevalent injuries among military personnel deployed in service of Operation Iraqi Freedom. Although several studies have evaluated symptoms after blast injury in military personnel, few studies compared them to nonblast injuries or measured symptoms within the acute stage after traumatic brain injury (TBI). Knowledge of acute symptoms will help deployed clinicians make important decisions regarding recommendations for treatment and return to duty. Furthermore, differences more apparent during the acute stage might suggest important predictors of the long-term trajectory of recovery. This study evaluated concussive, psychological, and cognitive symptoms in military personnel and civilian contractors (N = 82) diagnosed with mild TBI (mTBI) at a combat support hospital in Iraq. Participants completed a clinical interview, the Automated Neuropsychological Assessment Metric (ANAM), PTSD Checklist-Military Version (PCL-M), Behavioral Health Measure (BHM), and Insomnia Severity Index (ISI) within 72 hr of injury. Results suggest that there are few differences in concussive symptoms, psychological symptoms, and neurocognitive performance between blast and nonblast mTBIs, although clinically significant impairment in cognitive reaction time for both blast and nonblast groups is observed. Reductions in ANAM accuracy were related to duration of loss of consciousness, not injury mechanism. PMID:21083963

Luethcke, Cynthia A; Bryan, Craig J; Morrow, Chad E; Isler, William C

2011-01-01

190

Psychiatric emergencies (part I): psychiatric disorders causing organic symptoms.  

PubMed

Psychiatric emergencies are conditions that mostly destabilize the already frenetic activity of the Emergency Department. Sometimes the emergency is clearly referable to primitive psychiatric illness. Other times, psychiatric and organic symptoms can independently coexist (comorbidity), or develop together in different conditions of substance abuse, including alcohol and prescription drugs. Differentiating between substance induced and pre-existing psychiatric disorder (dual diagnosis) may be difficult, other than controversial issue. Finally, an organic disease can hide behind a psychiatric disorder (pseudopsychiatric emergency). In this review (part I), psychiatric disorders that occur with organic symptoms are discussed. They include: (1) anxiety, conversion and psychosomatic disorders, and (2) simulated diseases. The physiologic mechanisms of the stress reaction, divided into a dual neuro-hormonal response, are reviewed in this section: (1) activation of the sympathetic nervous system and adrenal medulla with catecholamine production (rapid response), and (2) activation of the hypothalamic-pituitary-adrenal axis with cortisol production (slow response). The concept of the fight-or-flight response, its adaptive significance and the potential evolution in paralyzing response, well showing by Yerkes-Dodson curve, is explained. Abnormal short- and long-term reactions to stress evolving toward well codified cluster of trauma and stressor-related disorders, including acute stress disorder, adjustment disorder and post-traumatic stress disorder, are examined. A brief review of major psychiatric disorder and related behaviour abnormalities, vegetative symptoms and cognitive impairment, according to DMS IV-TR classification, are described. Finally, the reactive psychic symptoms and behavioral responses to acute or chronic organic disease, so called "somatopsychic disorders", commonly occurring in elderly and pediatric patients, are presented. The specific conditions of post-operative and intensive care unit patients, and cancer and HIV positive population are emphasized. PMID:23436668

Testa, A; Giannuzzi, R; Sollazzo, F; Petrongolo, L; Bernardini, L; Daini, S

2013-02-01

191

What Are the Signs and Symptoms of Fanconi Anemia?  

MedlinePLUS

... What Are the Signs and Symptoms of Fanconi Anemia? Major Signs and Symptoms Your doctor may suspect ... sisters also should be tested for the disorder. Anemia The most common symptom of all types of ...

192

Web-Based Intervention for Returning Veterans with Symptoms of Posttraumatic Stress Disorder and Risky Alcohol Use  

Microsoft Academic Search

A substantial number of military personnel who have served in Iraq (Operation Iraqi Freedom; OIF) and Afghanistan (Operating\\u000a Enduring Freedom; OEF) develop symptoms of posttraumatic stress disorder (PTSD) in response to their military experiences\\u000a and many of these same individuals will drink in a risky or problematic manner following deployment. If left untreated, PTSD\\u000a symptoms and alcohol problems can become

Amy Rubin; Justin L. Enggasser; Monica Roy; Terence M. Keane

193

Prevalence of andropausal symptoms among Kuwaiti males.  

PubMed

Andropause is a syndrome that usually occurs during men's midlife. It is associated with clinical short-term and long-term effects, as well as some physiological and psychological symptoms due to subnormal levels of testosterone serum. The objective of this study was to identify the factors that significantly contribute to the prevalence of symptoms that may be related to androgen deficiency. The study used a cross-sectional structured questionnaire and a sample of 214 Kuwaiti men aged 40 years and older. The questionnaire consisted of the sociodemographic characteristics of the participants and the Androgen Deficiency of the Aging Male Scale of Andropausal Symptoms. The results of the study indicate that Kuwaiti men who were 40 to 49 years old reported fewer symptoms than did Kuwaiti men aged 50 years and older, including deterioration in their ability to play sports, easily falling asleep after dinner, anger, and hot flushes (p < .05); and Kuwaiti men aged 50 years and older reported experiencing decrease in muscle strength, decrease in sport performance, sweating, loss of height, decreased libido, as well as falling asleep after dinner. For those aged 40 to 49 years, lower education levels, marital status, and employment status were significantly associated with the men's symptoms (p < .05). On the other hand, in the case of respondents aged 50 years and older, only education level was significantly associated with their symptoms (p < .05). This is a preliminary study that reports the prevalence of aging male symptoms among Kuwaiti men. The findings will offer insight into the necessary health care provisions to educate, treat, and provide information related to andropause for the general public. PMID:23640979

Maha, Al-Sejari

2013-11-01

194

Symptom burden among patients with Renal Cell Carcinoma (RCC): content for a symptom index  

PubMed Central

Background Renal cell carcinoma (RCC) has multiple symptoms stemming from disease and treatments. There are few validated scales for evaluating RCC symptoms. Methods A national cross-sectional study of adult RCC patients was conducted from October to December 2003 to define patient-reported RCC symptomology. Participants were asked open-ended questions regarding their signs and symptoms and completed an 86-item pilot questionnaire of physical and psychological symptoms. Patients were asked to rate the relevancy and clarity of each pilot question using a 5-point Likert scale. Subsequent open-ended caregiver interviews and a provider panel relevance ranking contributed additional information. Results The average age of the participants (n = 31) was 55 years; 55% of patients were male, 74% had attended college, and 97% were Caucasian. The five most frequent symptoms among localized-stage patients (n = 14) were irritability (79%), pain (71%), fatigue (71%), worry (71%), and sleep disturbance (64%). Among metastatic patients (n = 17), the five most frequent symptoms were fatigue (82%), weakness (65%), worry (65%), shortness of breath (53%), and irritability (53%). More than 50% of localized and metastatic-stage patients reported pain, weakness, fatigue, sleep disturbance, urinary frequency, worry, and mood disorders as being moderately to highly relevant. Conclusion A brief, self-administered RCC Symptom Index was created that captures the relevant signs and symptoms of both localized and metastatic patients. Pending additional content validation, the Index can be used to assess the signs and symptoms of RCC and the clinical benefit resulting from RCC treatment.

Harding, Gale; Cella, David; Robinson, Don; Mahadevia, Parthiv J; Clark, Jason; Revicki, Dennis A

2007-01-01

195

Reviewing the Dissociative Symptoms in Patients With Schizophreniaand their Association With Positive and Negative Symptoms  

PubMed Central

Objective: The present study aimed to clarify dissociative symptoms in patients with schizophrenia and its association with negative and positive symptom of schizophrenia. Methods: Based on the 4th edition of Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria, 80 schizophrenic subjects were randomly selected from patients who referred to the clinics of psychiatry hospital in Kerman, Iran. Eighty non-schizophrenic patients were chosen as the control group. Both groups were evaluated for dissociation symptom using the Dissociative Experience Scale (DES). Positive and Negative Syndrome Scale (PANSS) score was also used in the case group for determination of positive and negative symptom of schizophrenia. Results: The prevalence of dissociation symptom was 13% and 4% among schizophrenic and control groups, respectively (p = 0.02). In addition, there was a statistical significant association between DES score and positive symptom in schizophrenia (p = 0.02). Conclusion: The association between dissociative symptom and schizophrenia was significant and dissociative symptoms were associated with positive symptoms of schizophrenia. Declaration of interest: None.

Ghoreishi, Abolfazl; Shajari, Zahra

2014-01-01

196

Depressive symptoms in institutionalized older adults.  

PubMed

OBJECTIVE To estimate the prevalence of depressive symptoms among institutionalized elderly individuals and to analyze factors associated with this condition. METHODS This was a cross-sectional study involving 462 individuals aged 60 or older, residents in long stay institutions in four Brazilian municipalities. The dependent variable was assessed using the 15-item Geriatric Depression Scale. Poisson's regression was used to evaluate associations with co-variables. We investigated which variables were most relevant in terms of presence of depressive symptoms within the studied context through factor analysis. RESULTS Prevalence of depressive symptoms was 48.7%. The variables associated with depressive symptoms were: regular/bad/very bad self-rated health; comorbidities; hospitalizations; and lack of friends in the institution. Five components accounted for 49.2% of total variance of the sample: functioning, social support, sensory deficiency, institutionalization and health conditions. In the factor analysis, functionality and social support were the components which explained a large part of observed variance. CONCLUSIONS A high prevalence of depressive symptoms, with significant variation in distribution, was observed. Such results emphasize the importance of health conditions and functioning for institutionalized older individuals developing depression. They also point to the importance of providing opportunities for interaction among institutionalized individuals. PMID:24897042

Santiago, Lívia Maria; Mattos, Inês Echenique

2014-04-01

197

Functional symptoms in neurology: questions and answers  

PubMed Central

Between 10 and 30% of patients seen by neurologists have symptoms for which there is no current pathophysiological explanation. The objective of this review is to answer questions many neurologists have about disorders characterised by unexplained symptoms (functional disorders) by conducting a multidisciplinary review based on published reports and clinical experience. Current concepts explain functional symptoms as resulting from auto-suggestion, innate coping styles, disorders of volition or attention. Predisposing, precipitating, and perpetuating aetiological factors can be identified and contribute to a therapeutic formulation. The sympathetic communication of the diagnosis by the neurologist is important and all patients should be screened for psychiatric or psychological symptoms because up to two thirds have symptomatic psychiatric comorbidity. Treatment programmes are likely to be most successful if there is close collaboration between neurologists, (liaison) psychiatrists, psychologists, and general practitioners. Long term, symptoms persist in over 50% of patients and many patients remain dependent on financial help from the government. Neurologists can acquire the skills needed to engage patients in psychological treatment but would benefit from closer working relationships with liaison psychiatry or psychology.

Reuber, M; Mitchell, A; Howlett, S; Crimlisk, H; Grunewald, R

2005-01-01

198

Managing dementia symptoms and needs using technology.  

PubMed

Dementia is a difficult and costly disease to manage. Although caregivers and patients have indicated they need support for activities of daily living and debilitating neuropsychological symptoms, most technology innovations focus on safety and social contact. This feasibility study tested a care technology designed to manage dementia symptoms and everyday routines using common, nonpharmacological interventions. It was implemented in two formal care environments (memory care, assisted living). In Sample 1, independent observers decided which symptoms were present or absent in individual residents pre-intervention and 1 and 2 months during the intervention. In Sample 2, independent observers determined the desired status (goals) for individual residents prior to intervention and evaluated resident status 1 and 2 months into the intervention. The intervention was associated with a reduction in symptoms and progression toward wellness goals, suggesting that nondrug interventions for managing symptoms and daily routines in dementia can be delivered effectively using advanced technology. [Journal of Gerontological Nursing, 40(7), 16-20.]. PMID:24892310

Kerssens, Chantal; Sattler, Melany; Monteiro, Alisha

2014-07-01

199

Secondhand Smoke Exposure and Depressive Symptoms  

PubMed Central

Objective To evaluate the association between secondhand smoke (SHS) exposure and depression. Tobacco smoking and depression are strongly associated, but the possible effects of SHS have not been evaluated. Methods The 2005 to 2006 National Health and Nutrition Examination Survey (NHANES) is a cross-sectional sample of the noninstitutionalized civilian U.S. population. SHS exposure was measured in adults aged ?20 years by serum cotinine and depressive symptoms by the Patient Health Questionnaire. Zero-inflated Poisson regression analyses were completed with adjustment for survey design and potential confounders. Results Serum cotinine-documented SHS exposure was positively associated with depressive symptoms in never-smokers, even after adjustment for age, race/ethnicity, gender, education, alcohol consumption, and medical comorbidities. The association between SHS exposure and depressive symptoms did not vary by gender, nor was there any association between SHS smoke exposure and depressive symptoms in former smokers. Conclusions Findings from the present study suggest that SHS exposure is positively associated with depressive symptoms in never-smokers and highlight the need for further research to establish the mechanisms of association.

Bandiera, Frank C.; Arheart, Kristopher L.; Caban-Martinez, Alberto J.; Fleming, Lora E.; McCollister, Kathryn; Dietz, Noella A.; LeBlanc, William G.; Davila, Evelyn P.; Lewis, John E.; Serdar, Berrin; Lee, David J.

2009-01-01

200

Symptoms and microenvironmental measures in nonproblem buildings.  

PubMed

Symptoms commonly defined as the sick building syndrome were studied in a cross-sectional investigation of 147 office workers in five building areas using a linear-analog self-assessment scale questionnaire to define symptoms at a specific point in time. At the same time, the environment in the breathing zone was characterized by measuring thermal parameters (dry-bulb temperature, relative humidity, air speed, and radiant temperature), volatile organic compounds, respirable suspended particulates, noise and light intensity, and carbon dioxide and carbon monoxide levels. Demographic characteristics of the occupants and building characteristics were recorded. Up to 25% of the variance in regression models could be explained for mucous membrane irritation and central nervous system symptoms. These two symptom groups were related to the concentrations of volatile organic compounds, to crowding, to layers of clothing, and to measured levels of lighting intensity. Chest tightness was also related to lighting intensity. Skin complaints were related only to gender. Gender, age, and education failed to demonstrate a consistent relationship with symptom categories. This study suggests that the sick building syndrome may have specific environmental causes, including lighting and volatile organic compounds. PMID:2037908

Hodgson, M J; Frohliger, J; Permar, E; Tidwell, C; Traven, N D; Olenchock, S A; Karpf, M

1991-04-01

201

Mirabegron for male lower urinary tract symptoms.  

PubMed

Benign prostatic hyperplasia (BPH) is a common cause of lower urinary tract symptoms (LUTS) in men. Patients with BPH often present with a combination of obstructive and overactive bladder (OAB) symptoms. It is postulated that bladder outlet obstruction (BOO) from BPH results in concomitant OAB symptoms through ischemic induced variations in the response to neurotransmitters of both the detrusor and the urothelium. This altered response leads to the pathologic activation of the micturition reflex, generating sensory dysfunction and involuntary bladder contractions. Alpha-1 adrenoceptor antagonists (alpha-blockers) and 5-alpha reductase inhibitors (5-ARIs) are commonly used to treat the BOO caused by BPH. Anticholinergic agents are frequently used to treat concurrently OAB symptoms caused by the BOO. Unfortunately, anticholinergic medications demonstrate bothersome side effects and a theoretical risk of urinary retention. Basic science and clinical research has led to the development of a new class of pharmaceuticals for the treatment of overactive bladder with diminished risk of urinary retention and lacking many anticholinergic side effects. This novel compound, mirabegron (Mybertriq, Astellas Pharma US, Inc.), is a ??-adrenoceptor agonist and represents a promising new class of oral agents designed for the treatment of OAB symptoms, with minimal effect on voiding. PMID:23913200

Suarez, Oscar; Osborn, David; Kaufman, Melissa; Reynolds, W Stuart; Dmochowski, Roger

2013-12-01

202

Influence of aeroionotherapy on some psychiatric symptoms  

NASA Astrophysics Data System (ADS)

Negative aeroionotherapy (daily 15 50 min sittings, for 10 30 days) was applied in 112 patients with various psychiatric disorders, especially neuroses, with the aim of ameliorating certain symptoms (target symptoms). Corona and water air ion generators, as well as electro-aerosol generators, were used. The aeroionization (small air ion concentration), at the patient's respiration level, was moderate: n-=10,000 15,000/ml air; n+s?1,000/ml air; q=n+/n-?0.1. In most treated patients a diminution or even the disappearance of the target symptoms was obtained. Those obviously ameliorated under the influence of aeroionotherapy were: asthenia, depressive reactions, anxiety, irascibility, cephalea, insomnia, and general indisposition.

Deleanu, M.; Stamatiu, C.

1985-03-01

203

Perimenopausal migraine in women with vasomotor symptoms.  

PubMed

Migraine is affected by fluctuating estrogen levels so it is not surprising that the perimenopause is a time of peak rate of change of migraine prevalence in women. Evidence supports estrogen 'withdrawal' as one of the important triggers of menstrual attacks of migraine without aura, while high levels are associated with migraine aura. This mini review addresses the issues of diagnosing migraine, treating the symptoms of migraine, and controlling co-morbid migraine and hot flushes with hormonal and non-hormonal options. Maintaining a stable estrogen environment is the most effective treatment for vasomotor symptoms and can also benefit estrogen-withdrawal migraine. Using only the lowest doses necessary to control symptoms minimizes the risk of unwanted side effects. Non-hormonal options for both conditions are limited but there is evidence of efficacy for fluoxetine and venflaxine, with less evidence for gabapentin. PMID:22115567

MacGregor, E Anne

2012-01-01

204

Hypodermoclysis for Symptom Control in Terminal Care  

PubMed Central

Subcutaneous infusions of fluid and electrolytes can be used for replacement and correction of imbalance, by a method known as hypodermoclysis (HDC). Since April 1982, the Palliative Care Unit of the Edmonton General Hospital has been using this method for symptom control, titrating the rate of infusion against the severity of the symptoms, when the oral route was no longer available. If incompatible drugs have to be given at the same time, or if two drugs have to be given at different rates, two sites are used simultaneously. HDC is an adequate method of symptom control for terminal patients; it has advantages over intravenous, intermittent subcutaneous or intramuscular routes and rectal infusion, when used as described.

Hays, Helen

1985-01-01

205

Medically unexplained physical symptoms in emergency medicine  

PubMed Central

Medically unexplained physical symptoms (MUPS) are physical symptoms for which no relevant organic pathology can be found. Patients with MUPS commonly present to the emergency department (ED) but are rarely considered in emergency medicine teaching or literature. Management of these patients is frequently more challenging than where there is an obvious organic pathology. This review provides the emergency physician with background knowledge regarding the classification and aetiology of MUPS. It then provides strategies for more effective management, such as exploring the contribution of psychosocial factors with patients, explaining negative test results, and providing reassurance and avoiding creating iatrogenic anxiety. Early recognition of the fact that symptoms may not result from organic disease and an appreciation of the role of psychosocial factors may improve outcomes by reducing unnecessary investigation and admission, and avoiding reinforcement that encourages further similar presentations and unhelpful coping mechanisms.

Stephenson, D T; Price, J R

2006-01-01

206

Methylphenidate-induced mania-like symptoms  

PubMed Central

Therapeutic dose of methylphenidate is known to cause adverse effects (psychosis or mania), albeit in a small number of cases. Signs and symptoms of adverse effects usually disappear on stopping the medicine. Data regarding the safety of methylphenidate in comorbid attention deficit hyperactivity disorder (ADHD) and mental retardation are nonexistent. We describe a case of an 11-year-old girl with ADHD and mental retardation treated with methylphenidate, who developed mania like symptoms requiring inpatient treatment. The index case required psychopharmacological intervention with sodium valproate and olanzapine as the symptoms did not subside even after 3 days. This case highlights the fact that one has to exercise caution while prescribing methylphenidate in patients with comorbid ADHD and mental retardation.

Chakraborty, Kaustav; Grover, Sandeep

2011-01-01

207

Marital satisfaction and depressive symptoms in China.  

PubMed

Although there is substantial evidence that low marital satisfaction is a significant risk factor for depression, little research has examined this relationship in cultures outside of the U.S. and Europe. The validity of the marital discord model of depression in Chinese culture was tested by studying 391 couples living in Beijing and Hangzhou, China. Results of structural equation modeling using an actor-partner interdependence model strategy indicated that husbands' and wives' marital satisfaction was significantly predictive of their own depressive symptoms. In addition, wives' marital satisfaction significantly predicted husbands' depressive symptoms. These results provide evidence that the marital discord model of depression is useful in understanding the role of marital dissatisfaction as a risk factor for depressive symptoms in collectivistic societies, such as China. PMID:23834363

Miller, Richard B; Mason, Tiffany M; Canlas, Jerevie M; Wang, Dahua; Nelson, David A; Hart, Craig H

2013-08-01

208

Identifying symptom clusters in paediatric cancer patients using the Memorial Symptom Assessment Scale.  

PubMed

This descriptive correlational study determined symptom prevalence, characteristics and distress in a sample of 54 children newly diagnosed with cancer in a paediatric oncology inpatient department and its associated outpatient clinics in Izmir, Turkey. Data were collected using the Memorial Symptom Assessment Scale 1, 2 and 3 months after diagnosis. Demographic data were collected using a questionnaire developed by the researchers while information on respondents' disease status and treatment regimens was obtained from medical records. Cluster analysis techniques were used to identify symptom clusters in the sample. The study identified a number of symptom clusters affecting children or adolescents (age range 10 to 18 years), although different clusters became apparent at each data collection point. The most common symptoms in newly diagnosed respondents were lack of appetite, nausea, lethargy, hair loss and feelings of sadness. Four symptom clusters were apparent 1 month after diagnosis, five in the second month and four in the third month. The study demonstrated that respondents experienced a wide range of symptoms in the months immediately following a cancer diagnosis and the start of treatment, which are findings that can be used to develop clinical guidelines for symptom assessment and management in children and adolescents with cancer. PMID:22335457

Atay, S; Conk, Z; Bahar, Z

2012-07-01

209

Big Five Dimensions and ADHD Symptoms: Links Between Personality Traits and Clinical Symptoms  

Microsoft Academic Search

Attention-deficit\\/hyperactivity disorder (ADHD) in adulthood is conceptualized as originating in childhood. Despite considerable theoretical interest, little is known about how ADHD symptoms relate to normal personality traits in adults. In 6 studies, the Big Five personality dimensions were related to ADHD symptoms that adults both recalled from childhood and reported concurrently (total N = 1,620). Substantial effects emerged that were

Joel T. Nigg; Oliver P. John; Lisa G. Blaskey; Cynthia L. Huang-Pollock; Erik G. Willcutt; Stephen P. Hinshaw; Bruce Pennington

2002-01-01

210

Dynamic Associations between Maternal Depressive Symptoms and Adolescents' Depressive and Externalizing Symptoms  

ERIC Educational Resources Information Center

The current prospective study investigated transactional relations between maternal depressive symptoms and children's depressive and externalizing symptoms. Participants included 240 children (M age = 11.86 years, SD = 0.56; 53.9% female) and their mothers who were part of a 6-year longitudinal study. Measures of maternal depression (Beck…

Kouros, Chrystyna D.; Garber, Judy

2010-01-01

211

Symptom Prevalence and Clustering of Symptoms in People Living with Chronic Hepatitis C Infection  

Microsoft Academic Search

Quality of life has been shown to be poor among people living with chronic hepatitis C. However, it is not clear how this relates to the presence of symptoms and their severity. The aim of this study was to describe the typology of a broad array of symptoms that were attributed to hepatitis C virus (HCV) infection. Phase 1 used

Carolyn A. Lang; Sue Conrad; Lyndall Garrett; Diana Battistutta; W. Graham E. Cooksley; Michael P. Dunne; Graeme A. Macdonald

2006-01-01

212

Clinical evaluation of early cognitive symptoms.  

PubMed

The etiology of cognitive impairment in older adults is almost always a clinical diagnosis without definitive biomarkers. The clinical evaluation, therefore, is indispensable. Evaluating cognitive symptoms requires a deliberate approach to define the onset, course, and nature of symptoms. An informant who knows the patient well is essential. The physician must have a working knowledge of the basics of cognitive function. The neurologic examination also is fundamental to defining the origin of cognitive impairment. Extraocular movements, speech, and gait are examples of high-yield examination findings that can be observed and tested quickly, adding to the clinical impression. PMID:24094297

McCarten, J Riley

2013-11-01

213

Longitudinal modelling of respiratory symptoms in children  

NASA Astrophysics Data System (ADS)

A panel of 277 children, aged 3-7 years, was used to study the association between air pollution (O3, SO2, NO2, and total suspended particles), meteorological factors (global radiation, maximum daytime temperature, daily averages of vapour pressure and air humidity) and respiratory symptoms. For 759 days the symptoms were recorded in a diary and modelling was based on a modification of the method proposed by Korn and Whittemore (Biometrics 35: 795-798, 1979). This approach (1) comprises an extension using environmental parameters at different time scales, (2) addresses the suitability of using the daily fraction of symptomatic individuals to account for inter-individual interactions and (3) enables the most significant weather effects to be identified. The resulting model consisted of (1) an individual specific intercept that takes account of the population's heterogeneity, (2) the individual's health status the day before, (3) a long-term meteorological effect, which may be either the squared temperature or global radiation in interaction with temperature, (4) the short-term effect of sulfur dioxide, and (5) the short-term effect of an 8-h ozone concentration above 60 µg/m3. Using the estimated parameters as input to a simulation study, we checked the quality of the model and demonstrate that the annual cycle of the prevalence of respiratory symptoms is associated to atmospheric covariates. Individuals suffering from allergy have been identified as a group of a particular susceptibility to ozone. The duration of respiratory symptoms appears to be free of scale and follows an exponential distribution function, which confirms that the symptom record of each individual follows a Poisson point-process. This supports the assumption that not only respiratory diseases, but also respiratory symptoms can be considered an independent measure for the health status of a population sample. Since a point process is described by only one parameter (namely the intensity of the point process), it is appropriate for records of respiratory symptoms to identify only one model which covers both the occurrence and duration of symptoms.

Schlink, Uwe; Fritz, Gisela; Herbarth, Olf; Richter, Matthias

2002-08-01

214

THEMIS Operations  

Microsoft Academic Search

THEMIS—a five-spacecraft constellation to study magnetospheric events leading to auroral outbursts—launched on February 17,\\u000a 2007. All aspects of operations are conducted at the Mission Operations Center at the University of California at Berkeley.\\u000a Activities of the multi-mission operations team include mission and science operations, flight dynamics and ground station\\u000a operations. Communications with the constellation are primarily established via the Berkeley

M. Bester; M. Lewis; B. Roberts; J. McDonald; D. Pease; J. Thorsness; S. Frey; D. Cosgrove; D. Rummel

2008-01-01

215

Assessment of Symptoms During Gastric Emptying Scintigraphy to Correlate Symptoms to Delayed Gastric Emptying  

PubMed Central

Background Symptoms of gastroparesis based on patient recall correlate poorly with gastric emptying. Aim To determine if symptoms recorded during gastric emptying scintigraphy (GES) correlate with gastric emptying and with symptoms based on patient recall. Methods Patients undergoing GES completed the Patient Assessment of GI Symptoms (PAGI-SYM) assessing symptoms over the prior 2 weeks and a questionnaire for which patients graded six symptoms during GES. A Symptom Severity Index (SSI) represented the mean of six symptoms at each time point. Key Results 560 patients underwent GES for clinical evaluation of symptoms. Of 388 patients included in the study: 232 patients had normal GES (NGES), 156 delayed GES (DGES), and 11 rapid GES (RGES). SSI increased pre- to postprandial for each group: NGES: 0.51±0.07 to 0.92±0.03, DGES: 0.60±0.09 to 1.13±0.05, and RGES: 0.56±0.12 to 0.79±0.13. DGES patients had a higher postprandial SSI than NGES patients (1.13±0.05 vs 0.92±0.03, p<0.05). Postprandial symptoms of stomach fullness (1.9±0.12 vs 1.5±0.09; p=0.011), bloating (1.4±0.11 vs 1.1±0.09; p =0.033), and abdominal pain (1.1±0.08 vs 0.7±0.12; p=0.012) were higher in DGES than NGES. Symptom severity based on PAGI-SYM for 2 weeks prior to GES correlated with symptoms during the test for nausea (NGES r=0.61, DGES r=0.70), stomach fullness (NGES r=0.47, DGES r=0.60), and bloating (NGES r=0.62, DGES r=0.66). Conclusions & Inferences Stomach fullness, bloating, and abdominal pain recorded during GES were higher in patients with delayed gastric emptying than in patients with normal gastric emptying. Symptoms recorded during GES correlated with those during daily life by patient recall.

Khayyam, Umar; Sachdeva, Priyanka; Gomez, Javier; Ramzan, Zeeshan; Smith, Michael S.; Maurer, Alan H.; Fisher, Robert S.; Parkman, Henry P.

2014-01-01

216

Negative symptoms in schizophrenia: their evolution during an acute phase  

Microsoft Academic Search

Whereas the instability of positive symptoms over time is well recognized, the instability of negative symptoms is still debated. This controversy could be due to the fact that different negative symptoms have been studied in different phases of schizophrenia. We, therefore, hypothesized that some negative symptoms would improve whereas others would remain perfectly stable during the remission of the acute

Sonia Dollfus; Michel Petit

1995-01-01

217

Effects of breastfeeding on hypoestrogenic symptoms in postpartum women  

Microsoft Academic Search

Objective: To assess the frequency and severity of hypoestrogenic symptoms in lactating and nonlactating women during the postpartum period.Study design: Women were recruited in the immediate postpartum period and evaluated during the immediate postpartum period, at 3 weeks postpartum and at 6 weeks postpartum, using self-ranked symptoms questionnaires. Hypoestrogenic symptoms were assessed using a modified Kupperman index, a menopausal symptoms

Julie Kim; Carolyn Alexander; Lisa Korst; Sanjay Agarwal

2000-01-01

218

The Longitudinal Association between Oppositional and Depressive Symptoms across Childhood  

ERIC Educational Resources Information Center

Objective: Symptoms of oppositional defiant disorder (ODD) and depression show high rates of co-occurrence, both cross-sectionally and longitudinally. This study examines the extent to which variation in oppositional symptoms predict, variation in depressive symptoms over time, accounting for co-occurring depressive symptoms and measurement error.…

Boylan, Khrista; Georgiades, Katholiki; Szatmari, Peter

2010-01-01

219

Psychiatric symptoms in alpha-mannosidosis.  

PubMed

Alpha-mannosidosis is characterized by mild to moderate intellectual disability (ID), moderate to severe neurosensory hearing loss, frequent infections, psychomotor disturbances and skeletal dysmorphism. For the first time, a panel of nine alpha-mannosidosis patients with psychiatric symptoms is presented. The clinical picture has several similarities: a physical or psychological stressor precedes a rapid development of a state of confusion, delusions, hallucinations, anxiety and often depression leading to a severe loss of function. This usually lasts 3-12 weeks, and is followed by a period of somnolence and asthenia. It may be more prevalent in females. In four of the described patients search for organic causes of the syndrome was performed, but revealed only negative findings. Because of the limited number of cases no firm conclusion about the benefit of various psychotropic drugs can be drawn from our observation. Psychiatric symptoms could affect as many as 25% of patients with alpha-mannosidosis. First onset is typically in late puberty to early adolescence. The episodes may be recurrent, and of limited duration although medication may be necessary to alleviate symptoms. Our observations indicate that alpha-mannosidosis is associated with an increased risk of psychiatric symptoms. These should not be dismissed as part of the ID but should give rise to the initiation of adequate diagnostic work-up, treatment and support. PMID:16207285

Malm, D; Pantel, J; Linaker, O M

2005-11-01

220

Emotion Regulation and Depressive Symptoms in Preadolescence  

ERIC Educational Resources Information Center

This study examined associations among several measures of emotion regulation, and their links to depressive symptoms, in a sample of children ages 10-12 years old (N = 87). Both temporal features of emotion regulation and regulation processes involved in the evaluation, monitoring, and modification of emotion were assessed through parent and…

Siener, Shannon; Kerns, Kathryn A.

2012-01-01

221

Autism and ADHD: Overlapping and Discriminating Symptoms  

ERIC Educational Resources Information Center

Children with ADHD and autism have some similar features, complicating a differential diagnosis. The purpose of our study was to determine the degree to which core ADHD and autistic symptoms overlap in and discriminate between children 2-16 years of age with autism and ADHD. Our study demonstrated that 847 children with autism were easily…

Mayes, Susan Dickerson; Calhoun, Susan L.; Mayes, Rebecca D.; Molitoris, Sarah

2012-01-01

222

Symptom & Toxicity Management - National Cancer Institute  

Cancer.gov

With the help of the CCOPs, MB-CCOPs and Research Bases, more clinical trials than ever before are incorporating patient-reported outcomes to better capture the clinical benefit and risks of cancer therapies. CCOP network studies include symptom management, toxicity reduction, supportive and palliative care, and quality of life.

223

Does Early Adolescent Sex Cause Depressive Symptoms?  

ERIC Educational Resources Information Center

A recent study by the Heritage Foundation (Rector, Johnson, & Noyes, 2003) found evidence of a positive relationship between early sexual intercourse and depressive symptoms. This finding has been used to bolster support for funding abstinence only sex education. However, promoting abstinence will only yield mental health benefits if there is a…

Sabia, Joseph J.

2006-01-01

224

What Are the Symptoms of the Flu?  

MedlinePLUS Videos and Cool Tools

... Vaccine Program Office, U.S. Department of Health and Human Services, talks about the symptoms of the flu ... website managed by the U.S. Department of Health & Human Services 200 Independence Avenue, S.W. - Washington, D.C. ...

225

Neuropsychological Correlates of Early Symptoms of Autism  

PubMed Central

Both the medial temporal lobe and dorsolateral prefrontal cortex have been implicated in autism. In the present study, performance on two neuropsychological tasks—one tapping the medial temporal lobe and related limbic structures, and another tapping the dorsolateral prefrontal cortex—was examined in relation to performance on tasks assessing autistic symptoms in young children with autism, and developmentally matched groups of children with Down syndrome or typical development. Autistic symptoms included orienting to social stimuli, immediate and deferred motor imitation, shared attention, responses to emotional stimuli, and symbolic play. Compared with children with Down syndrome and typically developing children, children with autism performed significantly worse on both the medial temporal lobe and dorsolateral prefrontal tasks, and on tasks assessing symptoms domains. For children with autism, the severity of autistic symptoms was strongly and consistently correlated with performance on the medial temporal lobe task, but not the dorsolateral prefrontal task. The hypothesis that autism is related to dysfunction of the medial temporal lobe and related limbic structures, such as the orbital prefrontal cortex, is discussed.

Dawson, Geraldine; Meltzoff, Andrew N.; Osterling, Julie; Rinaldi, Julie

2013-01-01

226

Transient Neurologic Symptoms After Spinal Anesthesia  

Microsoft Academic Search

- We recently reported several cases consistent with tran- sient radicular irritation after spinal anesthesia with hy- perbaric 5% lidocaine. The present prospective, blind, nonrandomized study was performed to determine the incidence of these transient neurologic symptoms and to identify factors that might be associated with their occurrence. We studied 270 patients scheduled for gy- necologic or obstetric procedures under

Karl F. Hampl; Markus C. Schneider; Wolfgang Ummenhofer; Jurgen Drewe

1995-01-01

227

Management of Menopause-Related Symptoms.  

National Technical Information Service (NTIS)

This systematic evidence review focuses on five Key Questions relating to symptoms of menopause and their management, as specified by the Planning Committee for the National Institutes of Health State-of-the-Science Conference on Management of Menopause-R...

A. Nedrow E. Haney H. D. Nelson J. Miller L. Humphrey

2005-01-01

228

Psychiatric Symptoms in Children with Primary Headache  

ERIC Educational Resources Information Center

Objective: To examine the association of psychiatric symptoms with migraine and tension-type headache in children. Method: A questionnaire completed by 1,135 Finnish children in the sixth grade identified 154 children with migraine, 138 with tension-type headache, and 407 children who were headache-free. Seventy children were randomly selected…

Anttila, Pirjo; Sourander, Andre; Metsahonkala, Liisa; Aromaa, Minna; Helenius, Hans; Sillanpaa, Matti

2004-01-01

229

Explanatory style, expectations, and depressive symptoms  

Microsoft Academic Search

One hundred and fifty-five college students completed questionnaires measuring explanatory style, general expectations for future good and bad events, specific expectations for future good and bad events, and depressive symptoms. Structural equation modeling confirmed the prediction of the attributional reformulation of learned helplessness theory that the link between stability and globality of explanatory style and depression is mediated by expectations.

Christopher Peterson; Robert S. Vaidya

2001-01-01

230

Anorexia Nervosa: Its Symptoms and Possible Cures.  

ERIC Educational Resources Information Center

This document presents a definition and description of anorexia nervosa as a disorder that occurs predominantly in girls and that can affect 1 out of every 250 girls between the ages of 12 and 18 years. The existence of a distorted mental body image among anorexics is discussed and symptoms of the disorder are described, including amenorrhea…

Bingaman, David E.

231

Childhood stressors and symptoms of schizophrenia.  

PubMed

There are many psychiatric disorders for which severe adverse events in childhood have been shown to be significant risk factors. This is particularly true for schizophrenia. The authors designed this study to determine whether specific childhood stressors might contribute to the specific symptoms of schizophrenia and not merely to increased risk for the psychosis. The authors divided childhood stressors into two domains: 1-"Childhood Neglect" in which the stressor is passively experienced as in the case of absent parenting and 2-"Childhood Abuse" in which the trauma is actively inflicted as in the case of physical maltreatment. Data for the study consist of the cumulative anonymous records of 134 schizophrenia patients carefully separated by positive or negative symptomatology. MANOVA testing yielded a statistically significant finding; childhood neglect is correlated with negative symptoms of schizophrenia and childhood abuse is associated with positive symptoms of the psychosis. The authors speculate that type of childhood stressor may incubate the specific symptoms of adult schizophrenia. They also call for more research on this topic since this is the first study of its kind. PMID:23395837

Gallagher, Bernard J; Jones, Brian J

2013-10-01

232

Determining the cause of vulvovaginal symptoms.  

PubMed

Both patients and clinicians may incorrectly diagnose vulvovaginitis symptoms. Patients often self-treat with over-the-counter antifungals or home remedies, although they are unable to distinguish among the possible causes of their symptoms. Telephone triage practices and time constraints on office visits may also hamper effective diagnosis. This review is a guide to distinguish potential causes of vulvovaginal symptoms. The first section describes both common and uncommon conditions associated with vulvovaginitis, including infectious vulvovaginitis, allergic contact dermatitis, systemic dermatoses, rare autoimmune diseases, and neuropathic vulvar pain syndromes. The focus is on the clinical presentation, specifically 1) the absence or presence and characteristics of vaginal discharge; 2) the nature of sensory symptoms (itch and/or pain, localized or generalized, provoked, intermittent, or chronic); and 3) the absence or presence of mucocutaneous changes, including the types of lesions observed and the affected tissue. Additionally, this review describes how such features of the clinical presentation can help identify various causes of vulvovaginitis. PMID:18559121

Farage, Miranda A; Miller, Kenneth W; Ledger, William J

2008-07-01

233

Acute psychotic symptoms induced by topiramate  

Microsoft Academic Search

The incidence of psychosis during clinical trials of topiramate was 0.8%, not significantly different from the rate for placebo or reported rates of psychosis in patients with refractory epilepsy. We observed psychotic symptoms in five patients soon after initiation of topiramate therapy. We performed a retrospective chart review of the first 80 patients who began on topiramate after approval for

Adil Khan; Edward Faught; Frank Gilliam; Ruben Kuzniecky

1999-01-01

234

Children's Peer Victimization, Empathy, and Emotional Symptoms  

ERIC Educational Resources Information Center

This study investigated the concurrent and longitudinal relations among children's peer victimization, empathy, and emotional symptoms. The sample consisted of 175 children (85 girls, mean age = 6.1 years) recruited from kindergartens in Switzerland and followed for 1 year (Time 2). Parents and teachers reported on the children's emotional…

Malti, Tina; Perren, Sonja; Buchmann, Marlis

2010-01-01

235

Psychiatric Symptoms in Alpha-Mannosidosis  

ERIC Educational Resources Information Center

Alpha-mannosidosis is characterized by mild to moderate intellectual disability (ID), moderate to severe neurosensory hearing loss, frequent infections, psychomotor disturbances and skeletal dysmorphism. For the first time, a panel of nine alpha-mannosidosis patients with psychiatric symptoms is presented. The clinical picture has several…

Malm, D.; Pantel, J.; Linaker, O. M.

2005-01-01

236

Subjective symptoms and hypersensitivity to cellular telephones  

Microsoft Academic Search

Electromagnetic hypersensitivity has been reported to be caused by exposure to electromagnetic fields emitted from cellular telephones and cell-phone base stations. The prevalence varies considerably with geographic location. A particularly vexing challenge in studying this phenomenon is that the symptoms reported by electromagnetically hypersensitive individuals, such as headache and fatigue, are common and nonspecific: they may have many causes. A

James C. Lin

2004-01-01

237

The Relation between Insomnia Symptoms, Mood, and Rumination about Insomnia Symptoms  

PubMed Central

Study Objectives: Research suggests that rumination may play an important role in insomnia. Whereas some have suggested that rumination mainly relates to depression, the evidence suggests that there may be insomnia-specific rumination. This paper explores insomnia symptom rumination across two distinct samples of varying levels of depressed mood and insomnia symptom severity. Methods: The first sample consisted of nonclinical participants (N = 327) with a range of insomnia and depressed mood symptoms, and the second sample consisted of those who met both Major Depressive Disorder and Insomnia diagnoses (N = 66). Rather than relying on a measure developed for those with depression, we developed and tested an insomnia-specific measurement scale based on items from previous rumination studies and the addition of items derived from common daytime insomnia symptoms. Results: Internal consistency was highly acceptable across the two samples for the new insomnia-specific rumination measure (Cronbach ? was 0.93 and 0.94). In the first study, poor sleepers reported significantly higher levels of daytime symptom rumination than did good sleepers. Across both studies, rumination about daytime insomnia symptoms and depression were signifi-cantly correlated; however, insomnia rumination scores predicted insomnia even after controlling for depression. Moreover, in Study 2, insomnia-specific rumination was related to insomnia, but general depressive rumination was not predictive of insomnia. Conclusions: The findings provide support for the use of this insomnia-specific rumination scale; moreover the findings support previous observances regarding rumination about daytime insomnia symptoms that are not exclusive to depression. Citation: Carney CE; Harris AL; Falco A; Edinger JD. The relation between insomnia symptoms, mood, and rumination about insomnia symptoms. J Clin Sleep Med 2013;9(6):567-575.

Carney, Colleen E.; Harris, Andrea L.; Falco, Ashley; Edinger, Jack D.

2013-01-01

238

Dynamic Associations between Maternal Depressive Symptoms and Adolescents’ Depressive and Externalizing Symptoms  

Microsoft Academic Search

The current prospective study investigated transactional relations between maternal depressive symptoms and children’s depressive\\u000a and externalizing symptoms. Participants included 240 children (M age?=?11.86 years, SD?=?0.56; 53.9% female) and their mothers who were part of a 6-year longitudinal study. Measures of maternal depression (Beck\\u000a Depression Inventory), child depression (Children’s Depression Inventory), and children’s externalizing symptoms (Youth Self-Report\\u000a Form) were assessed annually. Data

Chrystyna D. Kouros; Judy Garber

2010-01-01

239

Influence of age on symptoms and signs in lumbar disc herniation  

Microsoft Academic Search

In a prospective and consecutive study we evaluated the prevalence of pain-related symptoms, the results of the strainght leg raising (SLR) test and neurological disturbances by age group in a total of 150 patients operated on due to lumbar disc herniation. On admission, all patients were interviewed, and pain at rest, at night and on coughing was recorded. Walking capacity

B. Jönsson; B. Strömqvist

1995-01-01

240

Peace Operations.  

National Technical Information Service (NTIS)

This manual provides guidance for the full range of peace operations, to include support to diplomacy (peacemaking, peace building, and preventive diplomacy), peacekeeping (PK), and peace enforcement (PE). It addresses the environment of peace operations,...

1994-01-01

241

Symptom association probability and symptom sensitivity index: preferable but still suboptimal predictors of response to high dose omeprazole  

Microsoft Academic Search

Background: Twenty four hour oesophageal pH monitoring is frequently used to quantify the association between a patient's symptom and gastro-oesophageal reflux. Three indices (symptom association probability (SAP), symptom index (SI), and symptom sensitivity index (SSI)) are used to quantify and establish this relation. Aims: The aim of the present study was to compare these indices against the omeprazole test (OT)

S A Taghavi; M Ghasedi; M Saberi-Firoozi; M Alizadeh-Naeeni; K Bagheri-Lankarani; M J Kaviani; L Hamidpour

2005-01-01

242

The relationship between clinical signs and dry eye symptoms  

PubMed Central

Purpose To evaluate (i) the relationship between traditional and new clinical tests (lid-wiper epitheliopathy (LWE), lid-parallel conjunctival folds (LIPCOF)) and dry eye symptoms in non-contact lens wearers, and (ii) that a combination of these tests can improve predictive ability for the development of dry eye symptoms. Methods Tear meniscus height (TMH), non-invasive break-up time (NIBUT), ocular hyperaemia, LIPCOF, phenol red thread test (PRTT), corneal and conjunctival staining, and LWE grades were observed in a cohort of 47 healthy, non-lens wearers (male=17, female=30, median age=35 years, range=19–70). Symptoms were assessed using the Ocular Surface Disease Index (OSDI). Results LWE was significantly correlated to both temporal and nasal LIPCOF (0.537?0.248, P<0.001). Significant correlations were found between NIBUT and TMH (r=0.461, P=0.001) and PRTT (r=0.640, P<0.001). OSDI scores were significant correlated to NIBUT, TMH, PRTT, LIPCOF, and LWE (r>?0.31? P<0.05). Significant discriminators of OSDI+/? were NIBUT (area under the receiver operative characteristic curve (AUC)=0.895), TMH (0.715), PRTT (0.781), LIPCOF (temporal/nasal/Sum 0.748/0.828/0.816), and LWE (0.749). Best predictive ability was achieved by combining NIBUT with nasal LIPCOF (AUC=0.944). Conclusions The individual tests NIBUT, TMH, PRTT, LIPCOF, and LWE were significantly, but moderately, related to OSDI scores. The strongest relationship appeared by combining NIBUT with nasal LIPCOF.

Pult, H; Purslow, C; Murphy, P J

2011-01-01

243

NEXT-GENERATION NEGATIVE SYMPTOM ASSESSMENT FOR CLINICAL TRIALS: VALIDATION OF THE BRIEF NEGATIVE SYMPTOM SCALE  

PubMed Central

The current study examined the psychometric properties of the Brief Negative Symptom Scale (BNSS), a next-generation rating instrument developed in response to the NIMH sponsored consensus development conference on negative symptoms. Participants included 100 individuals with a DSM-IV diagnosis of schizophrenia or schizoaffective disorder who completed a clinical interview designed to assess negative, positive, disorganized, and general psychiatric symptoms, as well as functional outcome. A battery of anhedonia questionnaires and neuropsychological tests were also administered. Results indicated that the BNSS has excellent internal consistency and temporal stability, as well as good convergent and discriminant validity in its relationships with other symptom rating scales, functional outcome, self-reported anhedonia, and neuropsychological test scores. Given its brevity (13-items, 15-minute interview) and good psychometric characteristics, the BNSS can be considered a promising new instrument for use in clinical trials.

Strauss, Gregory P.; Keller, William R.; Buchanan, Robert W.; Gold, James M.; Fischer, Bernard A.; McMahon, Robert P.; Catalano, Lauren T.; Culbreth, Adam J.; Carpenter, William T.; Kirkpatrick, Brian

2012-01-01

244

Big Five dimensions and ADHD symptoms: Links between personality traits and clinical symptoms  

Microsoft Academic Search

Attention-deficit\\/hyperactivity disorder (ADHD) in adulthood is conceptualized as originating in child- hood. Despite considerable theoretical interest, little is known about how ADHD symptoms relate to normal personality traits in adults. In 6 studies, the Big Five personality dimensions were related to ADHD symptoms that adults both recalled from childhood and reported concurrently (total N 1,620). Substantial effects emerged that were

Joel T. Nigg; Oliver P. John; Lisa G. Blaskey; Cynthia L. Huang-Pollock; Erik G. Willicut; Stephen P. Hinshaw; Bruce Pennington

2002-01-01

245

Evaluation and treatment of colonic symptoms.  

PubMed

Important considerations for constipation include: 1. Initial evaluation should evaluate for fecal incontinence, fecal impaction, medication side effects, concerning symptoms, underlying medical or metabolic issues and irritable bowel syndrome. 2. History and examination should be used to determine if a defecatory disorder is most likely. a. If defecatory disorder is likely, testing with balloon expulsion or anal manometry can be considered and, if confirmed, treatment with biofeedback (if testing not available, it is reasonable to trial fiber and laxatives because many patients have a mixed disorder). b. If it is unlikely, proceed with trial of fiber and/or osmotic laxatives. 3. If continued symptoms, consider trial of newer agent (lubiprostone or linaclotide). 4. If ineffective, consider testing for colon transit time and referral to gastroenterology. PMID:24758959

Pasanen, Mark E

2014-05-01

246

Metabolomic change precedes apple superficial scald symptoms.  

PubMed

Untargeted metabolic profiling was employed to characterize metabolomic changes associated with 'Granny Smith' apple superficial scald development following 1-MCP or DPA treatment. Partial least-squares discriminant analyses were used to link metabolites with scald, postharvest treatments, and storage duration. Models revealed metabolomic differentiation between untreated controls and fruit treated with DPA or 1-MCP within 1 week following storage initiation. Metabolic divergence between controls and DPA-treated fruit after 4 weeks of storage preceded scald symptom development by 2 months. alpha-Farnesene oxidation products with known associations to scald, including conjugated trienols, 6-methyl-5-hepten-2-one, and 6-methyl-5-hepten-2-ol, were associated with presymptomatic as well as scalded control fruit. Likewise, a large group of putative triterpenoids with mass spectral features similar to those of ursolic acid and beta-sitosterol were associated with control fruit and scald. Results demonstrate that extensive metabolomic changes associated with scald precede actual symptom development. PMID:19715334

Rudell, David R; Mattheis, James P; Hertog, Maarten L A T M

2009-09-23

247

Acupuncture for Cancer Pain and Related Symptoms  

PubMed Central

Cancer pain is one of most prevalent symptoms in patients with cancer. Acupuncture and related techniques have been suggested for the management of cancer pain. The National Comprehensive Cancer Network (NCCN®) guidelines for adult cancer pain recommends acupuncture, as one of integrative interventions, in conjunction with pharmacologic intervention as needed. This review presents the latest available evidence regarding the use of acupuncture for cancer pain. It also provides “actionable” acupuncture protocols for specific cancer pain conditions and related symptoms in order to provide more clinically relevant solutions for clinicians and cancer patients with pain. These conditions include postoperative cancer pain, postoperative nausea and vomiting, postsurgical gastroparesis syndrome, opioid-induced constipation, opioid-induced pruritus, chemotherapy-induced neuropathy, aromatase inhibitor-associated joint pain, and neck dissection-related pain and dysfunction.

Lu, Weidong; Rosenthal, David S

2013-01-01

248

Lung Function, Respiratory Symptoms, and Mortality  

Microsoft Academic Search

PURPOSE: This study examines the association between lung function [percentage predicted FEV1 (forced expiratory volume in 1 s)] and respiratory symptoms (asthma, bronchitis, wheeze, dyspnea) and mortality from all causes; coronary heart disease, stroke, cancer, and respiratory disease in a cohort of 2100 men and 2177 women in the Busselton Health Study followed for 20–26 years for mortality.METHODS: A total

Matthew W Knuiman; Alan L James; Mark L Divitini; Gerard Ryan; Helen C Bartholomew; A. W Musk

1999-01-01

249

Expressed Emotion, Attributions, and Schizophrenia Symptom Dimensions  

Microsoft Academic Search

Using a sample of 40 Anglo American family members of schizophrenic patients, the present study replicates and lends cross-cultural support for an attribution–affect model of expressed emotion (EE). Consistent with attribution theory, the authors found that highly critical relatives (high-EE) viewed the illness and associated symptoms as residing more within the patient's personal control as compared with less critical relatives

Amy G. Weisman; Keith H. Nuechterlein; Michael J. Goldstein; Karen S. Snyder

1998-01-01

250

Initial symptoms of nicotine dependence in adolescents  

Microsoft Academic Search

OBJECTIVES: It has been assumed that nicotine dependence has a slow onset and occurs only after prolonged daily use of tobacco. A cohort of young adolescents was followed to determine when the first symptoms of nicotine dependence occur with respect to the duration and frequency of tobacco use.\\u000aDESIGN: A cohort of 681 seventh grade students (age 12-13 years) from

Joseph R. DiFranza; Nancy A. Rigotti; Ann D. McNeill; Judith K. Ockene; Judith A. Savageau; Dorothy M. St. Cyr; Mardia A. Coleman

2000-01-01

251

Malignant peritoneal mesothelioma presenting with respiratory symptoms  

Microsoft Academic Search

.   Malignant peritoneal mesothelioma is a rare disease associated with mild, nonspecific abdominal symptoms and a wide spectrum\\u000a of imaging findings, with thickened mesentery and peritoneum being the most common ones. A case of a malignant peritoneal\\u000a mesothelioma presenting with manifestations of pulmonary disease is reported. Imaging evaluation revealed pleural, lung and\\u000a pericardial involvement together with retroperitoneal lymphadenopathy, little ascites

M. Daskalogiannaki; P. Prassopoulos; M. Raissaki; M. Tsardi; N. Gourtsoyiannis

2000-01-01

252

[Enterobius vermicularis causing symptoms of acute appendicitis].  

PubMed

The authors present a case of enterobiasis of the appendix. Enterobius infection is an uncommon cause of acute appendicitis. Preoperative diagnosis of pinworm infestation is almost impossible unless there is a strong clinical suspicion. Parasites may produce symptoms which resemble acute appendicitis. Careful observation of the appendix stump may lead to intraoperative diagnosis of enterobiasis. A quick diagnosis and appropriate treatment may prevent future complications. PMID:18799410

Antal, András; Kocsis, Béla

2008-08-01

253

[From psychiatric symptoms to paraneoplastic syndrome  

Microsoft Academic Search

Two patients, a 38-year-old man and a 32-year-old woman, were admitted to a psychiatric ward. The first patient suffered from a mood disorder, personality changes and complained of several, hitherto unexplained physical symptoms. Finally the patient was diagnosed with paraneoplastic cerebellar degeneration associated with Hodgkin's disease. The second patient presented with psychosis and panic disorders, but the condition was later

S. T. de Bot; L. D. A. Dorresteijn; C. A. Haaxma; A. C. Kappelle; B. P. C. van de Warrenburg

2008-01-01

254

Waiting for Symptoms - Gut-Check  

Cancer.gov

Your doctor may talk to you about “watchful waiting” as an approach for other medical situations. Unfortunately, this isn’t an option when it comes to colorectal cancer. Many people with colon cancer don’t experience symptoms until it’s too late. The recommended screening methods can find cancer or pre-cancerous polyps early, when they can be treated and removed. That’s why having a screening plan is important.

255

Poststroke Neuropsychiatric Symptoms and Pseudoseizures: A Discussion.  

PubMed

LESSONS LEARNED AT THE INTERFACE OF MEDICINE AND PSYCHIATRY: The Psychiatric Consultation Service at Massachusetts General Hospital (MGH) sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. Such consultations require the integration of medical and psychiatric knowledge. During their thrice-weekly rounds, Dr. Huffman and Dr. Stern discuss the diagnosis and management of conditions confronted. These discussions have given rise to rounds reports that will prove useful for clinicians practicing at the interface of medicine and psychiatry. PMID:15156236

Huffman, Jeff C.; Stern, Theodore A.

2003-04-01

256

Does uncomplicated diverticular disease produce symptoms?  

Microsoft Academic Search

A questionnaire dealing with bowel symptoms was administered to 97 outpatients referred for air-contrast barium enema. Subsequenlly, the barium enema was interpreted by a radiologist who did not know the results of the questionnaire. Forty-nine had normal x-rays, and 27 had uncomplicated diverticular disease. Weight loss, rectal bleeding, abdominal pain, and pain at night were as common in those with

W. Grant Thompson; Dilip G. Patel; Hardy Tao; Rama C. Nair

1982-01-01

257

Research on subjective symptoms and mobile telephony  

Microsoft Academic Search

In summary, the published laboratory research, to date, on electromagnetic hypersensitivity and subjective symptoms from exposures to cell-phone RF fields are very limited. One study suffered from a single-blind design, and the exposure conditions were not randomized. The other was a carefully executed, double-blind study with randomized exposures. The statistical strength was weakened by a small number of subjects in

James C. Lin

2005-01-01

258

Fate of Dyspeptic or Colonic Symptoms After Laparoscopic Cholecystectomy  

PubMed Central

Background/Aims Gallbladder diseases can give rise to dyspeptic or colonic symptoms in addition to biliary pain. Although most biliary pain shows improvement after cholecystectomy, the fates of dyspeptic or colonic symptoms still remain controversial. This study assessed whether nonspecific gastrointestinal symptoms improved after laparoscopic cholecystectomy (LC) and identified the characteristics of patients who experienced continuing or exacerbated symptoms following surgery. Methods Sixty-five patients who underwent LC for uncomplicated gallbladder stones or gallbladder polyps were enrolled. The patients were surveyed on their dyspeptic or colonic symptoms before surgery and again at 3 and 6 months after surgery. Patients' mental sanity was also assessed using a psychological symptom score with the Symptom Checklist-90-Revised questionnaire. Results Forty-four (67.7%) patients showed one or more dyspeptic or colonic symptoms before surgery. Among these, 31 (47.7%) and 36 (55.4%) patients showed improvement at 3 and 6 months after surgery, respectively. However, 18.5% of patients showed continuing or exacerbated symptoms at 6 months after surgery. These patients did not differ with respect to gallstone or gallbladder polyps, but differed in frequency of gastritis. These patients reported lower postoperative satisfaction. Patients with abdominal symptoms showed higher psychological symptom scores than others. However, poor mental sanity was not related to the symptom exacerbation. Conclusions Elective LC improves dyspeptic or colonic symptoms. Approximately 19% of patients reported continuing or exacerbated symptoms following LC. Detailed history-taking regarding gastritis before surgery can be helpful in predicting patients’ outcome after LC.

Kim, Gi Hyun; Lee, Hyo Deok; Kim, Min; Kim, Kyeongmin; Jeong, Yusook; Hong, Yong Joo; Kang, Eun Seok; Han, Joung-Ho; Choi, Jae-Woon; Park, Seon Mee

2014-01-01

259

Does early adolescent sex cause depressive symptoms?  

PubMed

A recent study by the Heritage Foundation (Rector, Johnson, & Noyes, 2003) found evidence of a positive relationship between early sexual intercourse and depressive symptoms. This finding has been used to bolster support for funding abstinence only sex education. However, promoting abstinence will only yield mental health benefits if there is a causal link between sexual intercourse and depression. Using the National Longitudinal Study of Adolescent Health (Add Health), I carefully examine the relationship between early teen sex and several measures of depression. Controlling for a wide set of individual level and family level observable characteristics, cross section estimates consistently show a significant positive relationship between early sexual activity for females and three measures of adverse mental health: self reported depression, a belief that one's life is not worth living, and serious thoughts of suicide. However, difference-in-difference estimates reflect no evidence of a significant relationship between early teen sex and depressive symptoms. These findings suggest that the positive association observed by Rector et al. (2003) can be explained by unmeasured heterogeneity. Thus, promoting abstinence among adolescents is unlikely to alleviate depressive symptoms PMID:16989034

Sabia, Joseph J

2006-01-01

260

Pets, allergy and respiratory symptoms in children.  

PubMed

The relationship between pet ownership and respiratory allergy and symptoms was investigated in a population of 3344 Dutch children of 6-12 years old. Pet ownership was defined by the presence of cats, dogs, birds and/or rodents in the home. The reported prevalence of respiratory allergy and symptoms was lower among children of current pet owners than among children of parents who owned no pets. When past pet ownership was taken into account, however, a different picture emerged. The lowest prevalence of respiratory allergy and symptoms was found in children of current pet owners who had no pets in the past. The next lowest prevalence was found in children of current pet owners who had had pets in the past also. The next highest prevalence was found in children who never had pets in their life. The highest prevalence of reported pet allergy, chronic cough, wheeze, attacks of shortness of breath with wheezing, and doctor-diagnosed asthma was found in children who had pets in the past but not anymore. Past cat ownership especially was associated with a high prevalence of pet allergy and doctor-diagnosed asthma. Almost 2% of the population reported to never have owned pets for health reasons, and more than 12% reported removing pets from the home for health reasons in the past. These results show that selective avoidance and removal of pets leads to distortions of cross-sectional associations between pet ownership and respiratory allergy and disease among children. PMID:1428490

Brunekreef, B; Groot, B; Hoek, G

1992-04-01

261

[Hyperprolactinemia: etiology, clinical symptoms, and therapy].  

PubMed

Hyperprolactinemia is one of the most common endocrinological disorders. The main clinical symptoms are limited to hypogonadism, which manifests as fertility disturbances, oligo- or amenorrhea in women, and libido loss, impotence, and fertility disturbances in men, as well as bone density disturbances (osteopenia, osteoporosis) and alactorrhea. Hyperprolactinemia is caused in most cases by drugs or it has an organic etiology (pituitary tumor:--prolactinoma). Differentiation between these two causes is very important for both therapeutic decisions and prognosis. In the medical treatment of a hyperprolactinemic condition dopamine receptors type D2 agonists are used. Such drugs have well-established high therapeutic efficiency (in the vast majority of patients they cause normalization of PRL serum level, tumor shrinkage, and withdrawal of the hyperprolactinemia-related symptoms and tumor mass). This is why they are the first line treatment for prolactinoma. In cases of a lack of pharmacological effect, drug intolerance or resistance, large tumors with accompanying compression symptoms' (tumor mass effect), dynamic tumor enlargement, or if a macroprolactinoma-affected woman desires pregnancy neurosurgery should be considered. Radiotherapy is used mainly as a supplement to surgical treatment. PMID:15761382

Ka?uzny, Marcin; Bolanowski, Marek

2005-01-01

262

Modeling the temporal complexities of symptoms.  

PubMed Central

OBJECTIVE: To analyze the temporal aspects of symptoms, including their temporal uncertainty, in order to develop a high-level conceptual data model representation of this domain. DESIGN: A basic tenet of existing temporal models is that events occur not only relative to a particular date or time, but also relative to the time of some other event. The time an event occurs, particularly when the event is a symptom being recalled by a patient or collected by a busy provider, is frequently incomplete or uncertain, and this uncertainty must also be represented in a temporal data model. The object-oriented modeling technique used in this study is becoming popular among U.S. medical informatics standards developers. RESULTS: A conceptual data model for the temporal aspects of symptom data, including temporal uncertainty, has been developed. The object-oriented modeling approach used enables the temporal objects and attributes defined in this model to be inherited by other medical objects, such as problems. CONCLUSIONS: The temporal comparators presented here have previously been defined, and may serve as the basis for standardizing the terms used to describe how one event temporally relates to another. In an attempt to achieve domain completeness, this study concentrated more on developing a model that is highly expressive than on developing one that is easily queried. This trade-off in representation versus "queryability" will require further analysis and may require modifications to the underlying model.

Dolin, R H

1995-01-01

263

An Examination of Family Adjustment among Operation Desert Storm Veterans  

ERIC Educational Resources Information Center

This study examined interrelationships among combat exposure, symptoms of posttraumatic stress disorder (PTSD), and family adjustment in a sample of male and female Operation Desert Storm veterans (N = 1,512). In structural equation models for both male and female veterans, higher combat exposure was associated with higher PTSD symptoms, which in…

Taft, Casey T.; Schumm, Jeremiah A.; Panuzio, Jillian; Proctor, Susan P.

2008-01-01

264

Operating Systems  

NSDL National Science Digital Library

Rashid Bin Muhammad at Kent State University presents his page of lectures notes and other instructional materials on operating systems. The site is divided into a number of topics about operating systems: history, structure, process, threads, Solaris-2, CPU / process scheduling, schedule algorithm, interprocess communication, deadlock, important UNIX commands, and references. The site is then followed by links to outside resources to help supplement the material presented here. This is a great resource for computer science instructors teaching students about operating systems.

Bin Muhammad, Rashid

2009-06-24

265

Symptom Increase Following a Functional Capacity Evaluation in Patients with Chronic Low Back Pain: An Explorative Study of Safety  

Microsoft Academic Search

Introduction: This study was performed to study intensity and duration of symptom increase following an FCE and to explore safety of an FCE. Methods: Included were 92 patients with chronic low back pain (CLBP), mean age 38.5 years, mean self-reported disability 12.5 (Roland Morris Disability Questionnaire). All patients underwent an FCE. Symptom increase was measured with a 2-item questionnaire. Operational

Michiel F. Reneman; Wietske Kuijer; Sandra Brouwer; H. R. Schiphorst Preuper; Johan W. Groothoff; Jan H. B. Geertzen; Pieter U. Dijkstra

2006-01-01

266

Somatic symptoms and health-related quality of life among treatment-seeking Canadian Forces personnel with PTSD.  

PubMed

This study examined the association between somatic complaints and health-related quality of life (HR-QoL) in treatment-seeking Canadian military personnel with military-related Posttraumatic Stress Disorder (PTSD). Current and former Canadian Forces (CF) members attending the Parkwood Hospital Operational Stress Injury Clinic in London, Ontario (N=291) were administered self-report questionnaires assessing number and severity of somatic complaints, PTSD and depressive symptom severity, and mental and physical health-related quality of life (HR-QoL) prior to commencing treatment. Regression analyses were used to identify the role of somatic complaints on physical and mental HR-QoL, after controlling for PTSD symptom cluster and depressive symptom severity. Somatic symptom severity accounted for only a small amount of the variance in mental HR-QoL after accounting for PTSD symptom cluster and depressive symptom severity, but accounted for a larger proportion of the variance in physical HR-QoL after accounting for PTSD cluster and depressive symptom severity. Understanding the role of somatization in the symptom-presentation of military personnel with PTSD may provide additional avenues for treatment with this population. PMID:24745465

St Cyr, Kate; McIntyre-Smith, Alexandra; Contractor, Ateka A; Elhai, Jon D; Richardson, J Don

2014-08-15

267

ADHD Symptoms Moderate the Relation Between ASD Status and Internalizing Symptoms in 3-6-Year-Old Children.  

PubMed

The current study sought to understand the relation between diagnostic status (autism spectrum disorders [ASD] versus typically developing) and internalizing problems in children with and without co-occurring attention deficit hyperactivity disorder (ADHD) symptoms. Participants were 88 children, ages 3:0-6:11, their parents and teachers. Findings indicated that ADHD symptoms moderated the relation between diagnostic status and depressive and somatic symptoms. High ADHD symptoms in children with ASD were associated with increased depressive and somatic symptoms compared to children with typical development. Findings suggest poor prognostic outcomes for children with ASD and co-occurring ADHD symptoms and highlight the need for early identification and targeted intervention. PMID:24242972

Wilson, Beverly J; Manangan, Christen N; Dauterman, Hayley A; Davis, Heather N

2014-06-01

268

Operation Success.  

ERIC Educational Resources Information Center

Operation Success is an innovative approach to dealing with potential dropout/high-risk students. The program operates out of the Center for Arts and Technology-Pickering Campus in Northern Chester County, Pennsylvania. The campus offers the students a full-day program, half academic, half vocational. The building of self-esteem and…

Lang, Susan; Teifel, Phyllis

269

Warehousing Operations.  

ERIC Educational Resources Information Center

Developed as part of the Marine Corps Institute (MCI) correspondence training program, this course on warehousing operations is designed to provide instruction in the procedures used in warehousing operations. Introductory materials include specific information for MCI students and a study guide (guidelines to complete the course). The 22-hour…

Marine Corps Inst., Washington, DC.

270

Matrix Operations  

NSDL National Science Digital Library

Created by Lewis Blake and David Smith of the Connected Curriculum Project, the purposes of this module are to experiment with matrix operations, especially multiplication, inversion, and determinants, and to explore applications to solving systems of linear equations. In the process of studying these matrix operations, we will learn how to use a helper application to carry out matrix computations.

Blake, Lewis; Smith, David

2010-06-24

271

Symptom overreporting obscures the dose-response relationship between trauma severity and symptoms.  

PubMed

We investigated whether symptom overreporting affects the dose-response relationship between self-reported abuse severity and psychiatric symptoms in two samples. The first sample (N=599) consisted of adults who had previously reported to a public commission that they had been witnesses to or victims of childhood sexual abuse by Roman Catholic Church representatives. The second sample (N=1756) consisted of general population respondents who indicated that they had been victims of non-familial childhood sexual abuse. Using a web-based data collection procedure, both samples completed the Brief Symptom Inventory (BSI-18), items addressing abuse severity, and items flagging symptom overreporting. Adjusting for overreporting reduced the proportion of participants with clinically raised BSI-18 scores from 60% to 47% in sample 1 and from 26% to 22% in sample 2. Also, in both samples, normal range reporting participants exhibited the typical dose-response relationship between trauma severity and BSI-18 scores, whereas this pattern was largely non-significant in overreporting participants. Our findings show that symptom overreporting has a psychometric impact that may obscure relationships between clinically relevant variables and should therefore preferably be monitored in surveys. PMID:24704260

Merckelbach, Harald; Langeland, Willie; de Vries, Gerard; Draijer, Nel

2014-07-30

272

Panic symptom clusters differentially predict suicide ideation and attempt.  

PubMed

Increasingly strong evidence links anxiety disorders in general and panic attacks in particular to suicidality. The underlying causes and specifics of this relation, however, remain unclear. The present article sought to begin addressing this question by clarifying the association between panic symptoms and suicidality. Data were sampled from the NESARC epidemiological data set from the US and analyzed as four independently, randomly selected subsets of 1000 individuals using structural equation modeling analyses and replicating results across samples. Evidence is presented for four symptom clusters (cognitive symptoms, respiratory distress, symptoms of alpha and beta adrenergic activation) and the differential association of each with suicidal ideation and attempts. Symptoms of alpha adrenergic activation predicted prior suicide attempt whereas cognitive symptoms predicted prior suicidal ideation. These findings were independent of comorbid major depressive disorder. It is suggested that assessment of suicide risk in the community includes the presentation of cognitive symptoms and symptoms related to alpha adrenergic activation. PMID:24439632

Rappaport, Lance M; Moskowitz, D S; Galynker, Igor; Yaseen, Zimri S

2014-05-01

273

Tuberculosis: Learn the Signs and Symptoms of TB Disease  

MedlinePLUS

... Learn the Signs and Symptoms of TB Disease Tuberculosis (TB) is a disease caused by bacteria that ... to recognize the signs and symptoms of TB. Tuberculosis (TB) is a disease caused by bacteria that ...

274

What Are the Signs and Symptoms of Pneumonia?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of Pneumonia? The signs and symptoms of pneumonia vary from ... have sudden changes in mental awareness. Complications of Pneumonia Often, people who have pneumonia can be successfully ...

275

Defining and measuring negative symptoms of schizophrenia in clinical trials.  

PubMed

Recent attention has focused on negative symptoms as a target for new therapeutic approaches including pharmacological agents, medical devices, and psychosocial treatments. Each of these approaches requires an instrument for measuring the severity of negative symptoms as well as changes in severity over time. The instrument selected should provide coverage for the domains of negative symptoms; it should be sensitive to change; it should be reliable and relatively brief; and it should be useful for large international trials. These criteria were used to evaluate a number of older instruments including the Schedule for the Assessment of Negative Symptoms (SANS), the Positive and Negative Symptoms Scale (PANSS), and the Negative Symptom Assessment Scale (NSA). Two newer scales, the Brief Negative Symptom Scale (BNSS) and the Clinical Assessment Interview for Negative Symptoms (CAINS) were developed following a National Institute of Mental Health consensus meeting and addressed some of the shortcomings of earlier instruments. PMID:24275698

Marder, Stephen R; Kirkpatrick, Brian

2014-05-01

276

Irritable Bowel: A Nursing Study of Symptoms and Coping.  

National Technical Information Service (NTIS)

This study investigated the patterning of gastrointestinal (GI) symptoms and coping strategies in symptomatic and asymptomatic women. A three-group repeated measures design was used to contrast the patterns of GI symptoms, GI function, psychological and s...

E. F. Bond

1996-01-01

277

What Are the Symptoms of Adrenal Gland Disorders?  

MedlinePLUS

... at night Headache Generalized weakness Congenital Adrenal Hyperplasia (CAH) Symptoms of CAH range from mild to serious. Some people with mild CAH are never diagnosed because their symptoms do not ...

278

Parent and Child Stress and Symptoms: An Integrative Analysis.  

ERIC Educational Resources Information Center

Assessed stressful life events and psychological symptoms of 211 children and young adolescents and their parents. Findings supported a model in which daily stressors mediated the relation between major life events and psychological symptoms for family members. (RJC)

Compas, Bruce E.; And Others

1989-01-01

279

What Are the Signs and Symptoms of Vasculitis?  

MedlinePLUS

... Fatigue (tiredness) General aches and pains Organ- or Body System-Specific Signs and Symptoms Vasculitis can affect specific organs and body systems, causing a range of signs and symptoms. Skin ...

280

What Are the Signs and Symptoms of Deep Vein Thrombosis?  

MedlinePLUS

... Are the Signs and Symptoms of Deep Vein Thrombosis? The signs and symptoms of deep vein thrombosis ( ... life-threatening problems if not treated. Deep Vein Thrombosis Only about half of the people who have ...

281

What Are the Signs and Symptoms of Varicose Veins?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of Varicose Veins? The signs and symptoms of varicose veins include: ... signs of other, more serious conditions. Complications of Varicose Veins Varicose veins can lead to dermatitis (der-ma- ...

282

What Are the Signs and Symptoms of Atherosclerosis?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of Atherosclerosis? Atherosclerosis usually doesn't cause signs and symptoms until ... concentrating. Rate This Content: Featured Video What is atherosclerosis? Atherosclerosis Clinical Trials Clinical trials are research studies ...

283

Posttraumatic stress symptoms in Navy personnel: prevalence rates among recruits in basic training.  

PubMed

Individuals in the military are often required to endure high levels of stress as a result of demanding operational requirements or deployments. Individuals who enter the military with pre-existing mental health problems such as posttraumatic stress disorder (PTSD) are likely to be at heightened risk of adverse reactions to military stressors. The present study documents the prevalence of PTSD symptoms among new Navy recruits and compares the prevalence of PTSD symptomology among recruits to prevalence rates that have been reported for comparable civilian populations. Results suggest that 15 percent of new Navy recruits are experiencing measurable symptoms of posttraumatic stress. Prevalence of these symptoms among Navy recruits is comparable to that among civilian adolescent and young adult populations. PMID:17292582

Stander, Valerie A; Merrill, Lex L; Thomsen, Cynthia J; Milner, Joel S

2007-01-01

284

Reduced Adverse Symptoms Once BP is Controlled  

PubMed Central

Study Objectives To describe trends in adverse drug reaction (ADR) scores as blood pressure (BP) came under control during a study of physician-pharmacist collaboration in the management of hypertension. Design Secondary analysis from a randomized controlled clinical trial. Setting Five primary care clinics affiliated with the University of Iowa, Iowa City, IA, USA. Subjects One hundred seventy-nine patients with uncontrolled primary hypertension aged 21-85 years taking 0-3 antihypertensive medications at baseline. Intervention Patient-reported symptoms suggestive of ADRs were recorded at each study visit using a structured ADR questionnaire. Social support (SS) and self-efficacy (SE) questionnaires were also administered at each study visit. Measurements and Main Results ADR scores decreased significantly from baseline to the end of the study (p<0.0001) in both the control (26.5 to 18.4) and intervention (29.9 to 22.7) groups although there were no differences between groups. Antihypertensive medication use increased for both intervention (1.5±1.0 to 2.4±0.9) and control (1.4±1.0 to 1.9±1.0) groups. We performed additional analyses on SE and SS to determine a potential reason for the reduction in adverse symptom scores despite an increase in medication use. Improvements in SE and SS scores were significantly and independently associated with improvement in ADR score (p<0.05). Conclusions ADR scores improved despite an increase in antihypertensive medication use. Improvements in SS and, to a lesser extent, SE are associated with improvements in ADR scores. Patients should not expect an increase in distressful symptoms as their BP becomes controlled with antihypertensive medications, especially when adequate social support is available.

Weber, Cynthia A.; Leloux, Megan R.; Carter, Barry L.; Farris, Karen B.; Xu, Yinghui

2008-01-01

285

Effects of neuregulin-1 genetic variation and depression symptom severity on longitudinal patterns of psychotic symptoms in primary care attendees.  

PubMed

A better understanding of the factors associated with psychotic symptoms could aid early identification and treatment of psychotic disorders. Previous studies have typically utilized cross-sectional study designs and have focused on individuals with psychotic disorders. Thus, examination of promising correlates of psychotic symptoms using longitudinal designs among more broadly defined populations is warranted. Two such correlates are neuregulin-1 (NRG1) genotypic variation and depression symptom severity. Both NRG1 and depression symptom severity have cross-sectional evidence for an association with psychosis but their affect on longitudinal patterns of psychotic symptoms and their potential interaction effects are less clear. Using repeated measures analysis of variance and covariance we modeled the main and interaction effects of NRG1 genotypic variation and depressive symptom severity on longitudinal psychotic symptom patterns in 301 primary care attendees assessed annually over 4 years. One-fifth (19.9%) of the participants reported one or more psychotic symptoms over the 4-year assessment period. We observed a curvilinear (i.e., cubic) association between depression symptom severity at baseline and longitudinal patterns of psychotic symptoms but did not observe a main effect for NRG1 genotypic variation on psychotic symptom patterns. However, NRG1 rs6994992 genotype moderated the curvilinear association between depression symptom severity and psychotic symptom patterns. Specifically, depression symptom severity had less of an effect on longitudinal psychotic symptoms among carriers of the rs6994992 TT genotype compared to CC and CT carriers. Our findings suggest a curvilinear association between depression symptom severity and longitudinal patterns of psychotic symptoms that is moderated by NRG1 genotype. PMID:24123921

Bousman, C A; Potiriadis, M; Everall, I P; Gunn, J M

2014-01-01

286

Physical Characteristics of Asteroid-like Comet Nucleus C/2001 OG108 (LONEOS)  

NASA Technical Reports Server (NTRS)

For many years several investigators have suggested that some portion of the near-Earth asteroid population may actually be extinct cometary nuclei. Evidence used to support these hypotheses was based on: observations of asteroid orbits and associated meteor showers (e.g. 3200 Phaethon and the Geminid meteor shower); low activity of short period comet nuclei, which implied nonvolatile surface crusts (e.g. Neujmin 1, Arend-Rigaux); and detections of transient cometary activity in some near-Earth asteroids (e.g. 4015 Wilson-Harrington). Recent investigations have suggested that approximately 5-10% of the near- Earth asteroid population may be extinct comets. However if members of the near-Earth asteroid population are extinct cometary nuclei, then there should be some objects within this population that are near their final stages of evolution and so should demonstrate only low levels of activity. The recent detections of coma from near-Earth object 2001 OG108 have renewed interest in this possible comet-asteroid connection. This paper presents the first high quality ground-based near-infrared reflectance spectrum of a comet nucleus combined with detailed lightcurve and albedo measurements.

Abell, P. A.; Fernandez, Y. R.; Pravec, P.; French, L. M.; Farnham, T. L.; Gaffey, M. J.; Hardersen, P. S.; Kusnirak, P.; Sarounova, L.; Sheppard, S. S.

2003-01-01

287

Breast cancer survivorship symptom management: current perspective and future development  

PubMed Central

SUMMARY Increasing numbers and longevity of cancer survivors has furthered our insight into the factors affecting their health outcomes, suggesting that multiple factors play a role (e.g., effects of cancer treatments and health behaviors). Emotional and physical symptoms may not always receive sufficient attention. In this short narrative review highlighting recent literature, we describe the most common physical and emotional symptoms of breast cancer survivors aged 50 years and older and outline a multidisciplinary symptom management approach, regardless of symptom etiology.

van Londen, G; Beckjord, EB; Dew, MA; Cuijpers, P; Tadic, S; Brufsky, A

2013-01-01

288

Somatic symptom disorder: an important change in DSM.  

PubMed

This paper describes the rationale for the new diagnosis of somatic symptom disorder (SSD) within DSM5. SSD represents a consolidation of a number of previously listed diagnoses. It deemphasizes the centrality of medically unexplained symptoms and defines the disorder on the basis of persistent somatic symptoms associated with disproportionate thoughts, feelings, and behaviors related to these symptoms. Data are presented concerning reliability, validity, and prevalence of SSD, as well as tasks for future research, education, and clinical practice. PMID:23972410

Dimsdale, Joel E; Creed, Francis; Escobar, Javier; Sharpe, Michael; Wulsin, Lawson; Barsky, Arthur; Lee, Sing; Irwin, Michael R; Levenson, James

2013-09-01

289

The question of symptom lateralization in conversion disorder  

Microsoft Academic Search

Objective: The purpose of this study was to determine whether or not conversion symptoms are lateralized. Studies have shown a predominant left-oriented manifestation of symptoms for most somatoform disorders. The reports in the literature on the lateralization of conversion symptoms, however, are rather conflicting. They show left-sided, right-sided, or no symptom lateralization in conversion disorders. Methods: One hundred fourteen patients

Karin Roelofs; Gérard W. B Näring; Franny C Moene; Cees A. L Hoogduin

2000-01-01

290

[Mental pain: is it a symptom?].  

PubMed

The psychiatrist is confronted by a variety of emotional states, ranging from sadness to exaltation. The term "psychache "has been used to describe depression with melancholic features. But can such mental pain be defined without reference to visible lesions or precise physical symptoms? We report pathophysiological evidence supporting this concept and show that it has implications for both treatment and prognosis. Cognitive studies have shown that the neurological substrate of physical pain is also activated by mental pain. Mental pain is associated with a risk of suicide and can be improved by analgesics, including opiates and ketamine. PMID:21171250

Gaillard, Raphaël; Loo, Henry; Olie, Jean-Pierre

2010-03-01

291

Medical Management of Lower Urinary Tract Symptoms  

PubMed Central

Lower urinary tract symptoms (LUTS) are a common complaint among aging men and are often caused by benign prostatic hyperplasia (BPH). A number of medical treatments for LUTS/BPH exist, such as ?-blockers, 5?-reductase inhibitors, anticholinergics, phosphodiesterase type 5 (PDE5) inhibitors, and combination therapies. Agonist binding of the ?1A-adrenergic receptor (AR), causing prostatic smooth muscle contraction, has been attributed to cause some LUTS. Therefore, medical therapy has aimed to block the ?1A-AR and improve LUTS. Determining which therapy to choose must take into account individual patient factors as well as cost and patient choice.

Laborde, Eric E; McVary, Kevin T

2009-01-01

292

Psychiatric Symptoms Associated with Focal Hand Dystonia  

PubMed Central

Myoclonus dystonia and idiopathic dystonia are associated with a greater frequency of obsessive compulsive disorder (OCD) and major depression. We investigated the frequency of OCD in 39 patients with primary focal hand dystonia (FHD) using a semistructured interview. OCD and subsyndromal OCD was diagnosed in 5 of 39 (12.82%) patients with FHD, whereas OCD occurs in 2.3% of the general population. Recurrent depression occurred in (7 of 39) 17.95% of patients with FHD along with a family history of depression in (16 of 39) 41.02%. Overlapping mechanisms manifesting as FHD may also predispose to OC symptoms and likely implicates a common striatal dysfunction.

Voon, Valerie; Butler, Tracy R.; Ekanayake, Vindhya; Gallea, Cecile; Ameli, Rezvan; Murphy, Dennis L.; Hallett, Mark

2014-01-01

293

The Rivermead Post Concussion Symptoms Questionnaire  

Microsoft Academic Search

Objective  To investigate the factor structure of the Rivermead Post Concussion Symptoms Questionnaire (RPQ) among individuals seen as\\u000a part of routine follow-up following traumatic brain injury.\\u000a \\u000a \\u000a \\u000a Methods  RPQ data from 168 participants was examined (mean age 35.2, SD 14.3; 89% with post traumatic amnesia duration < 24 hours)\\u000a six months after admission to an Accident & Emergency Department following TBI. Structural equation modelling was

Seb Potter; Eleanor Leigh; Derick Wade; Simon Fleminger

2006-01-01

294

Symptoms of schizophrenia: normal adaptations to inability.  

PubMed

The usual thinking about schizophrenia is that symptoms arise from altered gene products, irregularities in brain development, or interruptions of brain circuitry due to more fundamental causes still unknown. It is possible, however, that some of the diagnostic symptoms of this illness result from attempts at healing the primary unknown lesion, that they are, to use a metaphor, consequences of scab formation rather than of wound. Because too little is known at this time about basic intracellular flaws in schizophrenia, this paper, while hypothesizing precisely such a sequence (from damage to attempt at healing to symptom formation) uses examples from the more accessible psychological level. For instance, it is known that individuals suffering from schizophrenia struggle with interpersonal demands because they find them, on the whole, ambiguous and complex. Given these interpersonal inabilities, it is understandable that they protect themselves from the experience of failure through avoidance of social conduct and through relative isolation. Another example comes from the domain of cognition where a number of deficits have been shown to exist in people with schizophrenia. Aware of these difficulties, individuals with schizophrenia narrow their field of activities and compensate for deficiency by repetitive rituals and over-rehearsal. Side-lined and disregarded because of illness, it makes psychological sense that they draw attention to themselves in ways (eccentric clothes, unusual phraseology and tone of voice) that are judged by others as socially inappropriate. Unsuccessful in the customary pursuit of happiness (worldly success, material possessions, intimate relationships), it also makes sense that individuals with schizophrenia adopt habits and routines that are considered by others as impractical, illogical, and unfathomable. Adoption of this compensatory view of the origin of schizophrenia symptoms by clinical scientists does not markedly change treatment approaches and does not immediately lead to new discoveries. What it does is to situate the actions of those with schizophrenia clearly within the normal range of human behaviors and, as a consequence, it diminishes the stigma that attaches to severe mental illness. It evens the playing field between patient and therapist, making the psychiatrist less a zoo keeper and more a fellow traveler along a road that inevitably leads, for everyone, to physical and cognitive decline with attempts, some more successful than others, at compensation in the face of a difficult reality. PMID:17303346

Seeman, Mary V

2007-01-01

295

A common symptom of an uncommon disease.  

PubMed

Cancer of the colon is the second most common visceral cancer in the United States (lung cancer is the first). It is usually diagnosed in patients older than 40 years, with a peak incidence at 70 years of age. Rarely, are cases seen in the pediatric population. In this study, we report a case of a 13-year-old girl with an 11-month history of intermittent abdominal pain whose diagnosis was delayed due to vague symptoms and a low index of suspicion for this condition. PMID:21552148

Sia, Valerie May; Sia, Dominic C; Yamashiro, Darrell J; Middlesworth, William; Syed, Muhammad; Paudel, Govinda; Kirk, Russell; Kigongo-Mwesezi, Samuel; Rivlin, Kenneth; Leggiadro, Robert J

2011-07-01

296

Risk factors for work-related symptoms in northern California office workers  

SciTech Connect

In most episodes of health complaints reported in office buildings in the last-twenty years, causal factors have not been identified. In order to assess risk factors for work-related symptoms in office workers, a reanalysis was performed of previous studies, and an epidemiologic study was conducted. The reanalysis of data, showed remarkable agreement among studies. Air-conditioned buildings were consistently associated with higher prevalence of headache, lethargy, and eye, nose, or throat problems. Humidification was not a necessary factor for this higher prevalence. Mechanical ventilation without air-conditioning was not associated with higher symptom prevalence. A study was conducted among 880 office workers, within 12 office buildings selected without regard to worker complaints, in northern California. A number of factors were found associated with prevalence of work-related symptoms, after adjustment in a logistic regression model for personal, psychosocial, job, workspace, and building factors. Two different ventilation types were associated with increases Ln symptom prevalence, relative to workers in naturally ventilated buildings: mechanical supply and exhaust ventilation, without air conditioning and with operable windows; and air-conditioning with sealed windows. No study buildings were humidified. In both these ventilation types, the highest odds ratios (ORs) found were for skin symptoms (ORs-5.0, 5.6) and for tight chest or difficulty breathing (ORs-3.6, 4.3). Use of carbonless copies or photocopiers, sharing a workspace, carpets, new carpets, new walls, and distance from a window were associated with symptom increases. Cloth partitions and new paint were associated with symptom decreases.

Mendell, M.J.

1991-10-01

297

The Association between Cholecystectomy and Gastroesophageal Reflux Symptoms: A Prospective Controlled Study  

PubMed Central

Objective A large controlled prospective observational study to compare pre- and post-surgery changes in reflux symptoms between cholecystectomy and hernia repair surgery patients. Summary Background Data Six studies have suggested that gastroesophageal reflux worsens after cholecystectomy. However, these studies all had design limitations. Methods We recruited 302 patients scheduled to undergo elective cholecystectomy (study group) or hernia repair (controls) at two hospitals. Both groups filled out the validated Reflux Symptom Score (RSS) and Gastrointestinal Symptom Rating Scale (GSRS) questionnaires 1–15 days prior to and 4–12 weeks after the operation. Changes in symptom scores between the pre and post-surgery assessments were measured, and compared between the two groups. Results Baseline RSS and GSRS reflux subscores were higher in the study group than controls (1.44 vs. 1.02 and 1.91 vs. 1.43 respectively; p<0.05). There were no significant differences in any of the symptom score changes between the two groups except for the GSRS pain subscore, which decreased more in the study group than the control group (?0.59 vs. ?0.10; p<0.001). With regard to reflux, the RSS decreased by ?0.34 in the study group and ?0.14 in controls (p=0.27), while the GSRS reflux subscore decreased by ?0.32 in the study group and ?0.05 in controls (p=0.12). GSRS diarrhea and constipation subscores decreased slightly after surgery, to the same extent in both groups. Conclusions This large prospective controlled study, the only one using validated reflux symptom questionnaires, shows that cholecystectomy does not lead to an increase in reflux symptoms. As expected, GSRS pain subscores were decreased in the cholecystectomy group but not the controls.

Lin, Otto S.; Kozarek, Richard A.; Arai, Andrew; Gan, S. Ian; Gluck, Michael; Jiranek, Geoffrey C.; Kowdley, Kris V.; Triadafilopoulos, George

2013-01-01

298

Self-Report and Stability of Physical Symptoms by Adolescents.  

ERIC Educational Resources Information Center

Investigated physical complaints and their relationship to school-related stress in two adolescent samples. Overall, the two groups complained of more physical symptoms than did adult sample. Positive correlation between body symptoms and test-trait anxiety was highly significant. Gender differences in reporting symptoms were apparent only in…

Marschall, Peter

1989-01-01

299

Traumatic Stress Symptoms in Adolescent Organ Transplant Recipients  

Microsoft Academic Search

Objective. Symptoms of posttraumatic stress disorder (PTSD) after life-threatening medical ill- ness have been found to predict poor outcome in prelim- inary studies of adults and children. However, these symptoms are rarely recognized in general medical or pediatric settings. Here we report on the first large inves- tigation to assess prevalence and correlates of self-re- ported symptoms of posttraumatic stress

Lisa Libman Mintzer; Margaret L. Stuber; Debra Seacord; Marleen Castaneda; Violet Mesrkhani; Dorie Glover

300

Depressive symptoms in mothers of pre-school children  

Microsoft Academic Search

Background Depressive symptoms in mothers of young children can have serious consequences for the health of the child. In particular, children whose mothers are experiencing depressive symptoms are at significantly greater risk of poisoning and accidental injury. A mother’s risk of developing depressive symptoms has been shown to be related to socio-economic disadvantage, high levels of stress and a perceived

Caroline Mulvaney; Denise Kendrick

2005-01-01

301

Relieving Symptoms in Cancer: Innovative Use of Art Therapy  

Microsoft Academic Search

Art therapy has been used in a variety of clinical settings and populations, although few studies have explored its use in cancer symptom control. The specific aim of this study was to determine the effect of a 1-hour art therapy session on pain and other symptoms common to adult cancer inpatients. A quasi-experimental design was used (n=50). The Edmonton Symptom

Nancy Nainis; Judith A. Paice; Julia Ratner; James H. Wirth; Jerry Lai; Susan Shott

2006-01-01

302

Simple Identification of Complex ADHD Subtypes Using Current Symptom Counts  

ERIC Educational Resources Information Center

The results of the assessment of the accuracy of simple rules based on symptom count for assigning youths to attention deficit hyperactivity disorder subtypes show that having six or more total symptoms and fewer than three hyperactive-impulsive symptoms is an accurate predictor for the latent class sever inattentive subtype.

Volk, Heather E.; Todorov, Alexandre A.; Hay, David A.; Todd, Richard D.

2009-01-01

303

Immediate Effect on Overactive Bladder Symptoms following Administration of Imidafenacin  

Microsoft Academic Search

Introduction: One of the factors influencing the treatment compliance of patients with overactive bladder (OAB) symptoms is thought to be the time to reach clinical effectiveness after administering drugs. We investigated the immediate effect of imidafenacin on OAB symptoms. Patients and Methods: Imidafenacin (0.1 mg) was administered. OAB symptom scores (OABSS) were evaluated before administration, and at 2 and 4

Yasuhide Kitagawa; Masato Kuribayashi; Kazutaka Narimoto; Shohei Kawaguchi; Hiroshi Yaegashi; Mikio Namiki

2011-01-01

304

Prevalence of Chronic Fatigue Syndrome-Related Symptoms among Nurses  

Microsoft Academic Search

Chronic Fatigue Syndrome is an illness that is characterized by debilitating fatigue and a group of other related symptoms. Few epidemiological studies have been conducte4 and none have focused on a nursing population. The present study is the first to assess the prevalence of Chronic Fatigue Syndromerelated symptoms in a sample of nurses. Demographic characteristics, symptoms, and possible prevalence rates

Leonard A. Jason; Stephanie L. Taylor; Sharon Johnson; Stephen E. Goldston; Doreen Salina; Peter Bishop; Lynne Wagner

1993-01-01

305

Sleep disorder symptoms among nurses and nursing aides  

Microsoft Academic Search

Nurses and nursing aides (n = 418) currently working on a regular evening or day schedule were compared in terms of sleep disorder symptoms. The relationship between past nightwork and sleep disorder symptoms was also assessed. The prevalence of individual symptoms varied from 6 to 53%. Evening workers showed a pattern of sleep disorder compatible with sleep deprivation, whereas the

Claire Infante-Rivard; Marie Dumont; Jacques Montplaisir

1989-01-01

306

Smoking and depressive symptoms in Chinese elderly in Hong Kong  

Microsoft Academic Search

Objective: To examine the association between smoking and depressive symptoms among Chinese elderly in Hong Kong. Method: Cross-sectional data on smoking and depressive symptoms from 56 167 Chinese elderly aged 65 or over in Hong Kong were analysed using logistic regression. Results: Current smokers and former smokers were more likely to have depressive symptoms than never smokers. The adjusted odds

T. H. Lam; Z. B. Li; S. Y. Ho; W. M. Chan; K. S. Ho; M. P. Li; G. M. Leung

2004-01-01

307

Symptoms Predictive for the Later Development of Retinal Breaks  

Microsoft Academic Search

Objective: To identify symptoms in patients with iso- lated posterior vitreous detachment predictive for the later development of retinal breaks. Methods: Two hundred eighty consecutive patients seen with symptoms of posterior vitreous detachment were prospectively asked to complete a questionnaire detail- ing their symptoms. At the time of presentation and fol- low-up, all patients had a full ophthalmologic examina- tion

Koen A. van Overdam; Marijke Wefers Bettink-Remeijer; Paul G. Mulder; Jan C. van Meurs

2001-01-01

308

20 CFR 220.114 - Evaluation of symptoms, including pain.  

Code of Federal Regulations, 2012 CFR

...Evaluation of symptoms, including pain. 220.114 Section 220...claimant's symptoms, such as pain. (2) Consideration of objective...such as evidence of reduced joint motion, muscle spasm, sensory...effect those symptoms, such as pain, may have on the...

2012-04-01

309

20 CFR 220.114 - Evaluation of symptoms, including pain.  

Code of Federal Regulations, 2011 CFR

...Evaluation of symptoms, including pain. 220.114 Section 220...claimant's symptoms, such as pain. (2) Consideration of objective...such as evidence of reduced joint motion, muscle spasm, sensory...effect those symptoms, such as pain, may have on the...

2011-04-01

310

Prevalence and Correlates of Depressive Symptoms in Young Adolescents  

ERIC Educational Resources Information Center

Objectives: To assess prevalence of elevated depressive symptoms in young adolescents and examine associations between symptoms and sociodemographic and behavioral factors. Methods: Cross-sectional survey data from 3621 seventh grade students from 16 middle schools were analyzed. Results: Elevated depressive symptoms were reported by 40% of girls…

Kubik, Martha Y.; Lytle, Leslie A.; Birnbaum, Amanda S.; Murray, David M.; Perry, Cheryl L.

2003-01-01

311

Duration of symptoms in patients with infective endocarditis  

Microsoft Academic Search

Despite progress in the management of infective endocarditis, delays in diagnosis or prior antimicrobial treatment may adversely influence the symptom duration and outcome. The duration of symptoms in patients with infective endocarditis was studied in 683 cases among 653 patients with 703 episodes of the disease; patients were hospitalized within 10 days of symptom onset in 169 (24.7%) cases. Antimicrobial

Victor Sarli Issa; José Fabri; Pablo M. A. Pomerantzeff; Max Grinberg; Antonio Carlos Pereira-Barreto; Alfredo José Mansur

2003-01-01

312

The Negative Symptoms of Schizophrenia: A Cognitive Perspective  

Microsoft Academic Search

Recent reports of improvement in the negative symptoms of schizophrenia following targeted cognitive interventions have prompted interest in the cognitive underpinnings of these symptoms. This review integrates current experimental research with the phenomenological accounts of patients participating in cognitive therapy for these specific symptoms. We propose that, in addition to the well-established role of neurobiological factors in their development and

Neil A Rector; Aaron T Beck; Neal Stolar

2005-01-01

313

Trajectories of Postpartum Maternal Depressive Symptoms and Children's Social Skills  

ERIC Educational Resources Information Center

The vast majority of new mothers experience at least some depressive symptoms. Postpartum maternal depressive symptoms can greatly influence children's outcomes (e.g., emotional, cognitive, language, and social development). However, there have been relatively few longitudinal studies of how maternal depressive symptoms may influence children's…

Wu, Yelena P.; Selig, James P.; Roberts, Michael C.; Steele, Ric G.

2011-01-01

314

Conversion Disorder Presenting With Neurologic and Respiratory Symptoms  

Microsoft Academic Search

ave you ever been faced with medical or neurologic symptoms in a patient who, despite a thorough workup, does not appear to H have a medical or neurologic condition that explains those symptoms? Have you wondered how to address (and treat) these symptoms when you suspect that they may reflect a psychological or psychiatric etiology? If you have, then the

Joshuah L. Roffman; Theodore A. Stern

2005-01-01

315

A characteristic symptom of calcium deficiency in maize and sorghum  

Microsoft Academic Search

The appearance of the so?called “bull?whip”; in leaves of maize plants has been recognized as a calcium deficiency symptom. Another characteristic symptom, in which the leaf edges of maize plants become serrated and curl, is often observed when there is a low calcium supply, especially in solution cultures. The effects of several factors on this symptom were investigated using solution

T. Kawaski; M. Moritsugu

1979-01-01

316

Operative treatment of substernal goiters.  

PubMed

This report describes the operative experience in 72 patients with substernal goiters treated over the past 5.5 years. Even though the incidence of multinodular goiter has decreased in the United States due to the routine use of iodized salt, we continue to see a large number of patients with massive goiters, predominantly from Caribbean Islands. The diagnosis of substernal goiter was made on clinical examination augmented by such radiologic studies, as chest x-ray, barium esophagograms, airway films, and CT scans. Computed tomographic (CT) scanning was particularly helpful in evaluating the extent of substernal extension. Confirmation of the extent of disease was made at the time of operation. Ninety percent of the patients had tracheal deviation and 85% were symptomatic from airway compression. Esophageal compression was noted in 60% of the patients. All patients had a long history of goiter with recent onset of pressure symptoms. Flow-volume-loop studies were performed in 44% of the patients and were useful in the evaluation of pressure symptoms. However, the decision for operation was made primarily based on clinical evaluation of signs and symptoms. Sixteen patients in this group were admitted with acute airway distress requiring airway intubation or semi-emergency decompression. Only 1 patient required mediastinal splitting, while all others were operated by the cervical approach. The decision as to the extent of thyroidectomy was made at the time of operation. Drains were routinely used because of the large dead space. One patient developed a hematoma in the recovery room and required re-exploration.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:2753701

Shaha, A R; Alfonso, A E; Jaffe, B M

1989-01-01

317

Dimensions of depressive symptoms and smoking cessation  

PubMed Central

Because different psychopathologic components of depressive symptoms may have distinct etiologies, examining their differential effects on smoking cessation may elucidate mechanisms underlying the smoking-depression relationship. Negative affect (NA), somatic features (SF), low positive affect/anhedonia (PA), and interpersonal disturbance (IP) have been identified as unique dimensions of depression that can be measured using the Center for Epidemiologic Studies Depression Scale (CESD). This study examined common and unique associations between CESD subscales and baseline smoking characteristics, nicotine withdrawal, and relapse in 157 participants enrolled in a smoking cessation trial for heavy social drinkers. Each dimension was univariately associated with negative and positive reinforcement smoking motives. Only SF had unique relations with tolerance smoking motives and univariate associations with nicotine dependence severity. Only PA predicted cessation-related changes in withdrawal symptoms on quit day. Analyses predicting abstinence at 8, 16, and 26 weeks post quit date showed that NA, SF, and PA each univariately predicted relapse, ps?.0083. Only low PA predicted poorer outcomes incrementally to the other dimensions, even when controlling for level of nicotine dependence, smoking frequency, and history of major depression, p=.0018. Interventions targeting anhedonia and low positive affect may be useful for smokers trying to quit.

Leventhal, Adam M.; Ramsey, Susan E.; Brown, Richard A.; LaChance, Heather R.; Kahler, Christopher W.

2009-01-01

318

[Treatment of neuropsychiatric symptoms in Alzheimer's disease].  

PubMed

The overall goal of all therapeutic interventions in Alzheimer s disease (AD) is the optimisation of the adaptive functions and quality of life of these patients. The general strategy for the use of pharmacological interventions in the treatment of neuropsychiatric manifestations of AD includes the following: 1) An exhaustive evaluation of the psychiatric symptomatology; 2) Establish a hierachy of the simptoms to treat based on their severity of symptoms and on their impact on the caregiver; 3) The identification of an adequate agent based on the type of symptoms and subject s characteristics; 4) The initial use of low doses with gradual titration, and 5) Changing one drug at a time. Regarding psychotic symptons, the introduction of new agents (e.g., risperidone) has replaced the use of traditional treatments (e.g., thioridazine) in patients with AD. The presence of psychomotor agitation and aggression can be treated with great variety of drugs, such as antipsychotics, anticonvulsants, antidepressants, and sedatives. Selective serotonine re uptake inhibitors are the treatment of choice for depressive symptomatology. The cholinesterase inhibitors have shown to be useful in the treatment of hallucinations, anxiety and apathy. PMID:12436383

Kaufer, D

319

Mapping Cancer Patients' Symptoms to UMLS Concepts  

PubMed Central

A prerequisite for patient-friendly personal health records (PHR) is their ability to allow seamless integration of patient terminology with professional terminologies. In this work, we mapped a set of symptoms/problems from the self-assessment component of a cancer patient support system to concepts in the Unified Medical Language System (UMLS) Metathesaurus. Our objective was to learn how the UMLS can be used as a tool to connect patient terminology with professional vocabularies. The mapping to UMLS was done with the help of ten expert cancer nurses who evaluated concepts, their synonyms and placement in the source vocabulary hierarchical structure. The UMLS concepts were also compared with terms and phrases found in patient medical records that addressed the same set of symptoms. In this study we observed several problems related to the use of the UMLS Metathesaurus as a tool to connect from patient-level expressions to professional-level classification systems. More work is needed to increase interoperability between layperson health applications and clinical systems.

Slaughter, Laura; Ruland, Cornelia; Rotegard, Ann Kristin

2005-01-01

320

Operation: Breakthrough.  

National Technical Information Service (NTIS)

Operation Breakthrough is a technical program focusing on volume production of housing and technologically innovative ways of construction. It was conceived and developed in 1969 when several constraints on the housing industry -- limitations in the suppl...

1972-01-01

321

Matrix Operations  

NSDL National Science Digital Library

Created by Lewis Blake and David Smith for the Connected Curriculum Project, the purposes of this module are to experiment with matrix operations, espcially multiplication, inversion, and determinants, and to explore applications to solving systems of linear equations. In the process of studying these matrix operations, we will learn how to use a helper application to carry out matrix computations. This is one of a much larger set of learning modules hosted by Duke University.

Blake, Lewis; Smith, David

2010-04-29

322

Comparative Study of International Prostate Symptom Scores and Urodynamic Parameters in Men and Women with Lower Urinary Tract Symptoms  

Microsoft Academic Search

Background: We compared urinary symptoms and urodynamic parameters in men and women with lower urinary tract symptoms. Methods: A total of 164 individuals (76 men and 88 women) were rated according to the International Prostate Symptom Score and underwent a detailed urodynamic investigation. Patients were stratified by age into 2 groups, namely, those <50 years (the younger group) and those

Seung-June On; Ja Hyeon Ku

2006-01-01

323

Ethnic Differences in Symptoms Experienced During the Menopausal Transition  

PubMed Central

Our purpose in this study was to explore ethnic differences in symptoms experienced during the menopausal transition among four major ethnic groups in the U.S. using a feminist perspective. This was a cross-sectional correlational study among 158 midlife women. The instruments included are: questions on sociodemographic characteristics, health, and menopausal status, and the Midlife Women’s Symptom Index. The data were analyzed using descriptive and inferential statistics. Significant ethnic differences in the total number of symptoms (p<.01) were found. The most frequently reported symptoms differed by ethnicity. The symptoms experienced during the menopausal transition were significantly associated with some contextual factors.

Im, Eun-Ok

2009-01-01

324

Menstrual Symptoms in Adolescent Girls: Association with Smoking, Depressive Symptoms, and Anxiety  

Microsoft Academic Search

PurposeDysmenorrhea affects quality of life and contributes to absenteeism from school and work, thereby diminishing opportunities for successful psychosocial and cognitive development during adolescence. In adults, depression, anxiety, and smoking have an impact on menstrual cycles and dysmenorrhea. Associations between these problems have not been examined in adolescents. The purpose of this study was to examine relations between depressive symptoms

Lorah D. Dorn; Sonya Negriff; Bin Huang; Stephanie Pabst; Jennifer Hillman; Paula Braverman; Elizabeth J. Susman

2009-01-01

325

Symptom attribution after a plane crash: comparison between self-reported symptoms and GP records  

Microsoft Academic Search

BACKGROUND: On 4 October 1992, an El Al Boeing 747-F cargo aeroplane crashed on two apartment buildings in Amsterdam. Thirty-nine residents on the ground and the four crew members of the plane died. In the years after, a gradually increasing number of people attributed physical signs and symptoms to their presence at the disaster scene. AIM: To investigate the consistency

G. A. Donker; C. J. IJzermans; P. Spreeuwenberg; J. van der Zee

2002-01-01

326

Sensory and motor secondary symptoms as indicators of brain vulnerability  

PubMed Central

In addition to the primary symptoms that distinguish one disorder from the next, clinicians have identified, yet largely overlooked, another set of symptoms that appear across many disorders, termed secondary symptoms. In the emerging era of systems neuroscience, which highlights that many disorders share common deficits in global network features, the nonspecific nature of secondary symptoms should attract attention. Herein we provide a scholarly review of the literature on a subset of secondary symptoms––sensory and motor. We demonstrate that their pattern of appearance––across a wide range of psychopathologies, much before the full-blown disorder appears, and in healthy individuals who display a variety of negative symptoms––resembles the pattern of appearance of network abnormalities. We propose that sensory and motor secondary symptoms can be important indicators of underlying network aberrations and thus of vulnerable brain states putting individuals at risk for psychopathology following extreme circumstances.

2013-01-01

327

ACOG Practice Bulletin No. 141: management of menopausal symptoms.  

PubMed

Vasomotor and vaginal symptoms are cardinal symptoms of menopause. Vasomotor symptoms can be particularly troubling to women and are the most commonly reported menopausal symptoms, with a reported prevalence of 50-82% among U.S. women who experience natural menopause (1, 2). The occurrence of vasomotor symptoms increases during the transition to menopause and peaks approximately 1 year after the final menstrual period (3-5). The purpose of this document is to provide evidence-based guidelines for the treatment of vasomotor and vaginal symptoms related to natural and surgical menopause. (Treatment of menopausal symptoms in cancer survivors is discussed in the American College of Obstetricians and Gynecologists' Practice Bulletin Number 126, Management of Gynecologic Issues in Women With Breast Cancer.). PMID:24463691

2014-01-01

328

Neuropathic sensory symptoms: association with pain and psychological factors  

PubMed Central

Background A large number of population-based studies of chronic pain have considered neuropathic sensory symptoms to be associated with a high level of pain intensity and negative affectivity. The present study examines the question of whether this association previously found in non-selected samples of chronic pain patients can also be found in chronic pain patients with underlying pathology of neuropathic sensory symptoms. Methods Neuropathic sensory symptoms in 306 patients with chronic pain diagnosed as typical neuropathic pain, radiculopathy, fibromyalgia, or nociceptive back pain were assessed using the Pain DETECT Questionnaire. Two separate cluster analyses were performed to identify subgroups of patients with different levels of self-reported neuropathic sensory symptoms and, furthermore, to identify subgroups of patients with distinct patterns of neuropathic sensory symptoms (adjusted for individual response bias regarding specific symptoms). Results ANOVA (analysis of variance) results in typical neuropathic pain, radiculopathy, and fibromyalgia showed no significant differences between the three levels of neuropathic sensory symptoms regarding pain intensity, pain chronicity, pain catastrophizing, pain acceptance, and depressive symptoms. However, in nociceptive back pain patients, significant differences were found for all variables except pain chronicity. When controlling for the response bias of patients in ratings of symptoms, none of the patterns of neuropathic sensory symptoms were associated with pain and psychological factors. Conclusion Neuropathic sensory symptoms are not closely associated with higher levels of pain intensity and cognitive-emotional evaluations in chronic pain patients with underlying pathology of neuropathic sensory symptoms. The findings are discussed in term of differential response bias in patients with versus without verified neuropathic sensory symptoms by clinical examination, medical tests, or underlying pathology of disease. Our results lend support to the importance of using adjusted scores, thereby eliminating the response bias, when investigating self-reported neuropathic symptoms by patients.

Shaygan, Maryam; Boger, Andreas; Kroner-Herwig, Birgit

2014-01-01

329

Neuropsychiatric Symptoms and the Use of Complementary and Alternative Medicine  

PubMed Central

Objectives To assess the prevalence of complementary and alternative medicine (CAM) use by U.S. adults reporting neuropsychiatric symptoms and whether this prevalence changes based on the number of symptoms reported. Additional objectives include identifying patterns of CAM use, reasons for use, and disclosure of use with conventional providers in U.S. adults with neuropsychiatric symptoms. Design Secondary database analysis of a prospective survey. Participants A total of 23,393 U.S. adults from the 2007 National Health Interview Survey. Methods We compared CAM use between adults with and without neuropsychiatric symptoms. Symptoms included self-reported anxiety, depression, insomnia, headaches, memory deficits, attention deficits, and excessive sleepiness. CAM use was defined as use of mind—body therapies (eg, meditation), biological therapies (eg, herbs), or manipulation therapies (eg, massage) or alternative medical systems (eg, Ayurveda). Statistical analysis included bivariable comparisons and multivariable logistical regression analyses. Main Outcome Measures The prevalence of CAM use among adults with neuropsychiatric symptoms within the previous 12 months and the comparison of CAM use between those with and without neuropsychiatric symptoms. Results Adults with neuropsychiatric symptoms had a greater prevalence of CAM use compared with adults who did not have neuropsychiatric symptoms (43.8% versus 29.7%, P < .001); this prevalence increased with an increasing number of symptoms (trend, P < .001). Differences in the likelihood of CAM use as determined by the number of symptoms persisted after we adjusted for covariates. Twenty percent of patients used CAM because standard treatments were either too expensive or ineffective, and 25% used CAM because it was recommended by a conventional provider. Adults with at least one neuropsychiatric symptom were more likely to disclose the use of CAM to a conventional provider (47.9% versus 39.0%, P < .001). Conclusion More than 40% of adults with neuropsychiatric symptoms commonly observed in many diagnoses use CAM; an increasing number of symptoms was associated with an increased likelihood of CAM use.

Purohit, Maulik P.; Wells, Rebecca Erwin; Zafonte, Ross D.; Davis, Roger B.; Phillips, Russell S.

2013-01-01

330

[Symptoms diagnosis and treatment of dyscalulia].  

PubMed

Children with dyscalculia show deficits in basic numerical processing which cause difficulties in the acquisition of mathematical skills. This article provides an overview of current research findings regarding the symptoms, cause, and prognosis of dyscalculia, and it summarizes recent developments in the diagnosis, early intervention, and treatment thereof. Diagnosis has improved recently because newly developed tests focus not only on the math curriculum, but also on basic skills found to be impaired in dyscalculia. A controversial debate continues with regard to IQ achievement discrepancy. International studies have demonstrated the effectiveness of specialized interventions. This article summarizes the research findings from intervention studies, describes different treatment approaches, and discusses implications for clinical practice. PMID:23782565

Ise, Elena; Schulte-Körne, Gerd

2013-07-01

331

Bilastine for the relief of allergy symptoms.  

PubMed

Bilastine is a potent inhibitor of the histamine H1 receptor. It was recently approved in 28 countries of the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria in adults and children older than 12 years. Data from preclinical studies confirmed its selectivity for the histamine H1 receptor over other receptors, and demonstrated antihistaminic and antiallergic properties in vivo. Studies in healthy volunteers and patients have shown that bilastine does not affect driving ability, cardiac conduction or alertness. Bilastine has demonstrated a good safety profile, without serious adverse effects or antimuscarinic effects in clinical trials. There were no significant changes in laboratory tests, electrocardiograms or vital signs. In clinical studies, oral treatment with bilastine 20 mg once daily improved allergic rhinitis with greater efficacy than placebo and comparable to cetirizine and desloratadine. Bilastine 20 mg was more effective than placebo and equivalent to levocetirizine in chronic urticaria, relieving symptoms, improving quality of life and controlling sleep disorders. PMID:21573249

Sádaba Díaz de Rada, B; Azanza Perea, J R; Gomez-Guiu Hormigos, A

2011-04-01

332

Eating disorder symptoms in affective disorder.  

PubMed Central

Patients with Major Affective Disorder (MAD), Secondary Depression, Panic Disorder, and bulimia with and without MAD, were given the Eating Disorder Inventory, the Beck Depression Inventory, and the General Behavior Inventory at presentation. It was found that patients with MAD have a triad of eating disorder symptoms: a disturbance in interoceptive awareness, the sense of ineffectiveness, and a tendency toward bulimia. The data supported the concept that the sense of ineffectiveness is secondary to major depression. A disturbance in interoceptive awareness exists independently in bulimia nervosa and in MAD providing a common diathesis from which bulimia may arise given family and social pressure. Bulimics with MAD do not respond to treatment as readily as those without MAD. It is recomended that these two groups be treated separately.

Wold, P N

1991-01-01

333

Obsessive-compulsive symptoms in eating disorders.  

PubMed

Obsessive-compulsive symptoms were measured in a consecutive series of new referrals with anorexia nervosa (n = 29) and bulimia nervosa (n = 77). In contrast with previous reports, there was no significant difference on MOCI scores between eating disorder groups and normal controls. A consecutive series of 38 patients with bulimia nervosa then entered a structured treatment programme. Poor outcome cases had a higher score on the MOCI-doubting sub-scale. However, there was no significant difference in obsessive-compulsive scores between those who were binge-free and those who were bingeing daily at the end of treatment and there was no significant in outcome between high and low-scorers on the MOCI. This study fails to support the view that the eating disorders are a subtype of OCD. Previous conflicting results are attributed to selection bias and the effects of low body weight. PMID:2021372

Fahy, T A

1991-01-01

334

Pathology Case Study: Flu-Like Symptoms  

NSDL National Science Digital Library

This is a case study presented by the University of Pittsburgh Department of Pathology which presents a "37-year-old white female who was in excellent health until three years prior, when she developed flu-like symptoms." Visitors are given an extensive patient history along with pathologic findings, including images, and are given the opportunity to diagnose the patient. A "Final Diagnosis" section provides a discussion of the findings as well as references. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in cardiovascular pathology.

Klionsky, Bernard; Molina, J. T.; Nichols, Larry

2008-04-21

335

Green light induces shade avoidance symptoms.  

PubMed

Light quality and quantity affect plant adaptation to changing light conditions. Certain wavelengths in the visible and near-visible spectrum are known to have discrete effects on plant growth and development, and the effects of red, far-red, blue, and ultraviolet light have been well described. In this report, an effect of green light on Arabidopsis (Arabidopsis thaliana) rosette architecture is demonstrated using a narrow-bandwidth light-emitting diode-based lighting system. When green light was added to a background of constant red and blue light, plants exhibited elongation of petioles and upward leaf reorientation, symptoms consistent with those observed in a shaded light environment. The same green light-induced phenotypes were also observed in phytochrome (phy) and cryptochrome (cry) mutant backgrounds. To explore the molecular mechanism underlying the green light-induced response, the accumulation of shade-induced transcripts was measured in response to enriched green light environments. Transcripts that have been demonstrated to increase in abundance under far-red-induced shade avoidance conditions either decrease or exhibit no change when green light is added. However, normal far-red light-associated transcript accumulation patterns are observed in cryptochrome mutants grown with supplemental green light, indicating that the green-absorbing form of cryptochrome is the photoreceptor active in limiting the green light induction of shade-associated transcripts. These results indicate that shade symptoms can be induced by the addition of green light and that cryptochrome receptors and an unknown light sensor participate in acclimation to the enriched green environment. PMID:21852417

Zhang, Tingting; Maruhnich, Stefanie A; Folta, Kevin M

2011-11-01

336

RESPIRATORY FUNCTION AND SYMPTOMS IN ROPE MAKERS  

PubMed Central

This paper gives the results of a small environmental, symptomatic, and respiratory function study of byssinosis in a rope factory. An attempt was made to relate the changes in ventilatory function during the working day to the differing dust concentrations within the factory. The tests used included the forced expiratory volume, the forced vital capacity, and, in half the subjects, other derivatives of the forced expiratory spirogram. The inspiratory airways resistance was measured by the interrupter technique. Measurements were made at the beginning and end of a working shift on either a Monday or a Tuesday in 44 subjects, of whom 22 were in a relatively dusty part of the factory and 14, involved in making wire rope, were exposed to very little dust. None of the subjects had symptoms of byssinosis, but significant falls were found in the F.E.V.1·0, F.V.C., and other derivatives of the forced expiratory spirogram in those in the dusty parts of the factory. There was some evidence that the peak flow rate, the maximal mid-expiratory flow, and similar indices might be a little more sensitive as measures of the acute changes in ventilatory capacity during the day than the F.E.V.1·0 and F.V.C. There were no significant changes in the airways resistance by the interrupter technique but the results were rather variable. The fall in ventilatory capacity during the day was not greater in those with symptoms of chronic cough and sputum than in those without, nor did it seem to be related to smoking, but the number of subjects studied was small.

McKerrow, C. B.; Gilson, J. C.; Schilling, R. S. F.; Skidmore, J. W.

1965-01-01

337

Operating Systems  

NSDL National Science Digital Library

Stanford's Computer Science department presents this course on operating systems taught by David Mazières in Winter of 2009. The course covers concurrency, synchronization, scheduling, linking, virtual memory, memory allocations, file systems, networking, protection, security, and virtual machines. On the site, visitors will find the course syllabus, lecture notes, reference materials, and old exams from past iterations of the course. There are also four programming projects on the following topics: threads, user programs, virtual memory, and file systems. It's an excellent resource for educators in computer science and technician training courses to help supplement operating systems education.

Maziãâ¨res, David

2009-01-01

338

Operation Galileo  

NASA Technical Reports Server (NTRS)

The Operation Galileo education program took off with the first of four flights on board a U.S. Air Force C-130 transport aircraft from Keesler Air Force Base, Miss. Teachers from Mississippi and Louisiana participated in the program which aims to enhance math and science education of high-risk students by allowing junior high and middle school teachers, students and parents to fly in cargo and tanker aircraft during routine training missions. The Air Force Reserve created Operation Galileo, which was implemented by NASA's Educator Resource Center at Stennis.

1996-01-01

339

Rearing practices and impulsivity/hyperactivity symptoms in relation to inflated responsibility and obsessive-compulsive symptoms.  

PubMed

Smári, J., Rúrik Martinsson, D., & Einarsson, H. (2010). Rearing practices and impulsivity/hyperactivity symptoms in relation to inflated responsibility and obsessive-compulsive symptoms. Scandinavian Journal of Psychology. The aim of the study was to investigate potential precursors of inflated responsibility (responsibility attitudes) and obsessive-compulsive (OCD) symptoms. It was argued that both parental overprotection and impulsivity, separately and in interaction with each other, contribute to inflated responsibility and OCD symptoms. In a large sample of young adults (N = 570), self-report measures of OCD symptoms (OCI-R), responsibility attitudes (RAS), anxiety/depression (HADS), rearing practices (EMBU), present and past impulsivity/hyperactivity symptoms (IMP/HY) were administered. Overprotection as well as IMP/HY were found to predict OCD symptoms as well as inflated responsibility. Finally, a significant interaction was found between IMP/HY and overprotection with regard to both OCD symptoms and inflated responsibility. This effect reflected that IMP/HY was more strongly related to OCD symptoms and responsibility in people who had not been overprotected than in people who had been. Conversely overprotection was related to OCD symptoms and responsibility in people low but not in people high in IMP/HY. The results seem to indicate that the inadequacy between offer and need for parental control may play a role in the development of OCD symptoms. PMID:20584153

Smári, Jakob; Martinsson, Davíð Rúrik; Einarsson, Hjalti

2010-06-24

340

Posttraumatic Stress Disorder Symptoms Among Navy Recruits.  

National Technical Information Service (NTIS)

Individuals in the military are often required to endure high levels of stress as a result of demanding operational requirements or deployments. Individuals who enter the military with pre-existing mental health problems such as posttraumatic stress disor...

V. A. Stander L. L. Merrill C. J. Thomsen J. S. Milner

2005-01-01

341

Evaluation and management of post-transurethral resection of the prostate lower urinary tract symptoms.  

PubMed

Transurethral resection of the prostate (TURP) continues to be the most common treatment in the operative management of benign prostatic hypertrophy (BPH). Several other modalities have shown equivalence to TURP. However, even after surgical treatment, up to one third of patients have bothersome lower urinary tract symptoms (LUTS). This review discusses the pathophysiology, evaluation, and management options for patients with LUTS after TURP. PMID:25037906

Chughtai, Bilal; Simma-Chiang, Vannita; Kaplan, Steven A

2014-09-01

342

Operation Uplift...  

ERIC Educational Resources Information Center

Article described a model policy on student care and counseling for prevention of drug and alcohol dependency. It was adopted by the Department of School Nurses through funding by the National Education Association for Operation Uplift--Better Health for Better Learning. (Author/RK)

NJEA Review, 1975

1975-01-01

343

Operating Systems  

NSDL National Science Digital Library

CSC 342. Operating Systems (3) Prerequisite: CSC 332. Study of supervisory programs. System services and file systems; CPU scheduling; memory management; virtual memory; disk scheduling. Deadlock characterization, prevention, and avoidance; concurrent processes; semaphores; critical sections; synchronization. Distributed systems and communication protocols.

Ferner, Clayton

2003-04-21

344

Operant behavior  

Microsoft Academic Search

Reinforcement may be contingent, not only on the occurrence of a response, but on special features of its topography, on the presence of prior stimuli, and on scheduling systems. Operant techniques are important in defining the behavioral effects of physiological variables––surgical, electrical, and chemical––in specifying what aspects of behavior are to be attributed to hereditary endowment, in tracing features of

B. F. Skinner

1963-01-01

345

Operation Blowdown  

National Technical Information Service (NTIS)

This report on Operation BLOWDOWN describes an Australian field test in which a 50-ton HE charge was detonated over a typical rain forest at the Iron Range Test Site, North Queensland, Australia. U. S. participation included the establishment of a blast l...

J. R. Kelso C. C. Clifford

1964-01-01

346

Operation Highjump.  

National Technical Information Service (NTIS)

This program describes the Antarctic operation conducted during the Antarctic summer of 1946-47. Also known as task force 68, this mission conducted photographic flights involving six DC-3's from the Bay of Whales under the leadership of Admiral Byrd.

1994-01-01

347

Symptom Perception in Children with Asthma: Cognitive and Psychological Factors  

PubMed Central

Objective: This study tested the differential effects of several cognitive and psychological variables on children's perception of asthma symptoms by use of an Asthma Risk Grid. Children's subjective and objective assessments of PEFR (peak expiratory flow rate) were characterized as representing perceptual accuracy, symptom magnification, and/or underestimation of asthma symptoms. Design: Two hundred and seventy children with asthma (ages 7-17) and their primary caregivers completed measures assessing cognitive and psychological factors and a 5-6 week symptom perception assessment. Main Outcome Measures: Children's symptom perception scores by use of the Asthma Risk Grid. Results: Children's attentional abilities had more of a bearing on their symptom monitoring abilities than their IQ estimates and psychological symptoms. The more time children took on Trails and Cancellation Tasks and the fewer errors they made on these tasks, the more likely they were to perceive their asthma symptoms accurately. More time on these tasks were associated with more symptom magnification scores, and fewer errors were related with fewer symptom magnification scores. More errors and higher total scores on the Continuous Performance Task were associated with a greater proportion of scores in the danger zone. Conclusion: Statistical support was provided for the utility of attentional-based instruments for identifying children who may have problems with perceptual accuracy, and who are at risk for asthma morbidity.

Mitchell, Daphne Koinis; McQuaid, Elizabeth L.; Seifer, Ronald; Kopel, Sheryl J.; Nassau, Jack H.; Klein, Robert; Feldman, Jonathan; Wamboldt, Marianne Z.; Fritz, Gregory K.

2008-01-01

348

Factors influencing postconcussion and posttraumatic stress symptom reporting following military-related concurrent polytrauma and traumatic brain injury.  

PubMed

The purpose of this study was to identify factors that are predictive of, or associated with, high endorsement of postconcussion and posttraumatic stress symptoms following military-related traumatic brain injury (TBI). Participants were 1,600 U.S. service members (age: M = 27.1, SD = 7.1; 95.4% male) who had sustained a mild-to-moderate TBI and who had been evaluated by the Defense and Veterans Brain Injury Center at one of six military medical centers. Twenty-two factors were examined that included demographic, injury circumstances/severity, treatment/evaluation, and psychological/physical variables. Four factors were statistically and meaningfully associated with clinically elevated postconcussion symptoms: (i) low bodily injury severity, (ii) posttraumatic stress, (iii) depression, and (iv) military operation where wounded (p < .001, 43.2% variance). The combination of depression and posttraumatic stress symptoms accounted for the vast majority of unique variance (41.5%) and were strongly associated with, and predictive of, clinically elevated postconcussion symptoms [range: odds ratios (OR) = 4.24-7.75; relative risk (RR) = 2.28-2.51]. Five factors were statistically and meaningfully associated with clinically elevated posttraumatic stress symptoms: (i) low bodily injury severity, (ii) depression, (iii) a longer time from injury to evaluation, (iv) military operation where wounded, and (v) current auditory deficits (p < .001; 65.6% variance accounted for). Depression alone accounted for the vast majority of unique variance (60.0%) and was strongly associated with, and predictive of, clinically elevated posttraumatic stress symptoms (OR = 38.78; RR = 4.63). There was a very clear, strong, and clinically meaningful association between depression, posttraumatic stress, and postconcussion symptoms in this sample. Brain injury severity, however, was not associated with symptom reporting following TBI. PMID:24723461

Lange, Rael T; Brickell, Tracey A; Kennedy, Jan E; Bailie, Jason M; Sills, Cheryl; Asmussen, Sarah; Amador, Ricardo; Dilay, Angelica; Ivins, Brian; French, Louis M

2014-06-01

349

Symptoms in Children with Convergence Insufficiency: Before and After Treatment  

PubMed Central

Purpose To investigate symptom patterns and evaluate the relationship between patient characteristics and symptom severity before and after treatment for symptomatic children with convergence insufficiency (CI). Methods In a randomized clinical trial, the Convergence Insufficiency Symptom Survey (CISS) was administered pre- and post-treatment to 221 children 9 to <18 years with symptomatic CI. Frequency of symptom type was determined at baseline, mean change in performance-related versus eye-related symptoms for treatment responders was compared, and the relationship between patient characteristics and symptom severity at baseline for the entire cohort and after treatment for those who responded to treatment, was determined. Results At baseline, the score for performance-related symptoms was greater than that for eye-related symptoms (mean response of 2.3 vs. 1.8, p<0.001) regardless age, sex, race/ethnicity, or presence of parent-reported ADHD. Symptom severity increased with age for both the overall and eye-related subscale scores (p=0.048, p=0.022, respectively). Children with parent-reported ADHD were more symptomatic (p=0.005) than those without parent-reported ADHD because of a higher performance-related score (p<0.001). A significant and equal improvement (p<0.01) for the performance-related and eye-related symptoms was found in treatment responders. Girls had significantly lower performance-related symptoms than boys (p=0.014) and African-American children reported less eye-related symptoms than White children (p=0.022). Children without parent-reported ADHD had significantly less symptoms overall and less eye-related symptoms than children with parent-reported ADHD (p=0.019, p=0.011, respectively). Conclusions Because of a high frequency of both performance- and eye-related symptoms, clinicians should perform a targeted history that addresses both types of symptoms to help identify children with symptomatic CI. Future study regarding the relationship of CI and symptoms and their potential influence on ADHD, reading performance, and attention is warranted.

Barnhardt, Carmen; Cotter, Susan A.; Mitchell, G. Lynn; Scheiman, Mitchell; Kulp, Marjean T.

2012-01-01

350

Characteristics and treatability of oil-bearing wastes from aluminum alloy machining operations.  

PubMed

Enomoto Industry Co., exclusively uses water-based cutting fluids in its aluminum alloy machining operations. Since the cost of disposal can be much greater than the cost of purchase, the treatability of spent cutting fluids is becoming a major criterion for cutting fluid selection. Samples were collected from the machining lines at Enomoto's facility to determine their characteristics and evaluate their treatability with centrifugation, chemical coagulation and electrochemical coagulation. As expected, oil and grease (O&G) and total suspended solids (TSS) are the main reasons that spent cutting fluids are prohibited from being discharged into local swage systems. The average O&G found in the spent cutting fluids is 87,354 mg/L with TSS of more than 70,000 mg/L. Both O&G and TSS are the major contributors to the high turbidity of these waste effluents. A centrifuge with a relative centrifugal force of 1318 x g, was able to reduce 60% of the turbidity. By adding the coagulant aluminum chloride, the oil-water emulsion was destabilized, and the turbidity was reduced from 3249 Formazin Attenuation Units (FAU) to around 314 FAU. With freshly generated aluminum ions in the spent cutting fluid, the electrochemical process destabilized the oil-water emulsion system. The coalesced oil droplets were adsorbed onto the highly dispersed aluminum coagulant. The oil-rich sludge that was generated in the operation was then floated to the surface, forming a blanket that was removed by skimming. The electrochemical treatment was able to reduce the turbidity to less than 14 FAU, which is the detection limit of the Hach DR/4000 UV-vis spectrophotometer. PMID:17850956

Chen, Luke; Hsieh, Chueh-Chen; Wetherbee, John; Yang, Chen-Lu

2008-04-15

351

Perceived Symptoms in People Living with Impaired Glucose Tolerance  

PubMed Central

The aim of the study was to identify symptoms in people with impaired glucose tolerance (IGT) and describe their experiences of living with the symptoms which they related to their condition. Twenty-one participants, from a cross-sectional population-based study, diagnosed as having IGT, were invited for an interview. The interviews were analyzed in two phases by means of a manifest and latent content analysis. The narratives included seven categories of symptoms (and more than 25 different symptoms) presented by the respondents. This study shows that symptoms such as the patient's own interpretation of different perceptions in the body must be considered, as well as signs and/or objective observations. Symptoms ought to be seen as complementary components in the health encounter and health conversation. The results of this study indicate that health professionals should increase their awareness of the balance between the implicit and the explicit bodily sensations that individuals communicate. Further studies are needed.

Andersson, Susanne; Ekman, Inger; Lindblad, Ulf; Friberg, Febe

2011-01-01

352

Interpretation of Ambiguity in Individuals with Obsessive-Compulsive Symptoms  

PubMed Central

In two experiments we examined the psychometric properties of a new measure of interpretation bias in individuals with obsessive-compulsive symptoms (OCs). In Experiment 1, 38 individuals high in OC symptoms, 34 individuals high in anxiety and dysphoric symptoms, and 31 asymptomatic individuals completed the measure. Results revealed that the Word Sentence Association Test for OCD (WSAO) can differentiate those with OC symptoms from both a matched anxious/dysphoric group and a non-anxious/non-dysphoric group. In a second experiment, we tested the predictive validity of the WSAO using a performance-based behavioral approach test of contamination fears, and found that the WSAO was a better predictor of avoidance than an established measure of OC washing symptoms (Obsessive Compulsive Inventory-Revised, washing subscale). Our results provide preliminary evidence for the reliability and validity of the WSAO as well as its usefulness in predicting response to behavioral challenge above and beyond OC symptoms, depression, and anxiety.

Kuckertz, Jennie M.; Amir, Nader; Tobin, Anastacia C.; Najmi, Sadia

2013-01-01

353

Depressive Symptoms, Social Support, and Walking Among Hispanic Older Adults  

PubMed Central

Objectives Depressive symptoms and physical inactivity are health risks among minority older adults. This study examined whether social support moderated the relationship of depressive symptoms to walking behavior among 217 community-dwelling, Hispanic older adults. Method Cross-sectional analyses were used to test whether different forms of social support interacted with depressive symptoms to affect both likelihood and amount of walking. Results Analyses showed a significant interaction between depressive symptoms and instrumental support related to the likelihood of walking and a marginally significant interaction between depressive symptoms and instrumental social support related to the amount of walking. Depressive symptoms were associated with a lower likelihood and lower amount of walking among participants receiving high levels of instrumental social support (e.g., help with chores) but not low instrumental support. Emotional and informational support did not moderate the depression to walking relationship. Conclusion Receiving too much instrumental support was related to sedentary behavior among depressed older adults.

Perrino, Tatiana; Brown, Scott C.; Huang, Shi; Brown, C. Hendricks; Gomez, Gianna Perez; Pantin, Hilda; Szapocznik, Jose

2013-01-01

354

Symptom experience in patients with gynecological cancers: the development of symptom cIusters through patient narratives.  

PubMed

The vast majority of the increasing cancer literature on physical and psychological symptom clusters is quantitative, attempting either to model clusters through statistical techniques or to test priori clusters for their strength of relationship. Narrative symptom clusters can be particularly sensitive outcomes that can generate conceptually meaningful hypotheses for symptom cluster research. We conducted a study to explore the explanation of patients about the development and coexistence of symptoms and how patients at tempted to self-manage them. We collected 2-month qualitative longitudinal data over four assessment points consisting of 39 interview data sets from 10 participants with gynecological cancer. Participants' experiences highlighted the presence of physical and psychological symptom clusters, complicating the patients 'symptom experience that often lasted 1 year. While some complementary and self-management approaches were used to manage symptoms, few options and interventions were discussed. The cancer care team maybe able to develop strategies for a more thorough patient assessment of symptoms reported as the most bother so mean and patient-centered sensitive interventions that encompass the physiological, psychological, sociocultural, and behavioral components of the symptom experience essential for effectives symptom management. PMID:21542413

Lopez, Violeta; Copp, Gina; Brunton, Lisa; Molassiotis, Alexander

2011-01-01

355

Trajectories of children's internalizing symptoms: The role of maternal internalizing symptoms, respiratory sinus arrhythmia, and child sex  

PubMed Central

Background We assessed trajectories of children’s internalizing symptoms as predicted by interactions among maternal internalizing symptoms, respiratory sinus arrhythmia (RSA), and child sex. Method An ethnically and socio-economically diverse sample of children (n = 251) participated during three study waves. Children’s mean ages were 8.23 years (SD = 0.72) at T1, 9.31 years (SD = 0.79) at T2, and 10.28 years (SD = 0.99) at T3. Results Multiple-indicator multilevel latent growth analyses showed maternal internalizing symptoms interacted with child RSA and sex to predict children's internalizing symptoms. Girls with higher RSA whose mothers had lower levels of internalizing symptoms showed the steepest decline in internalizing symptoms across time. Girls with lower RSA whose mothers had higher levels of internalizing symptoms showed the highest levels of internalizing symptoms at T3, whereas boys with higher RSA whose mothers had higher levels of internalizing symptoms showed the highest levels of internalizing symptoms at T3. Conclusions Findings build on this scant literature and support the importance of individual differences in children's physiological regulation in the prediction of psychopathology otherwise associated with familial risk.

Wetter, Emily K.; El-Sheikh, Mona

2014-01-01

356

Operation Poorman  

SciTech Connect

The objectives of Operation Poorman were to design and build a portable seismic system and to set up and use this system in a cold-weather environment. The equipment design uses current technology to achieve a low-power, lightweight system that is configured into three modules. The system was deployed in Alaska during wintertime, and the results provide a basis for specifying a mission-ready seismic verification system.

Pruvost, N.; Tsitouras, J.

1981-03-18

357

ADHD-like symptoms and attachment in internationally adopted children  

Microsoft Academic Search

Internationally adopted children seem to be more likely to show ADHD-like symptoms than non-adopted children. The aims of this study were to explore the existence of ADHD-like symptoms and\\/or diagnosis in a sample of internationally adopted children depending on their country of origin and to describe the links that may exist between the display of these symptoms and observed narrative-based

Neus Abrines; Natalia Barcons; Diana Marre; Carme Brun; Albert Fornieles; Victoria Fumadó

2012-01-01

358

Irritable bowel-type symptoms in HMO examinees  

Microsoft Academic Search

A study of irritable bowel-type symptoms in 1264 health examinees using a selfadministered questionnaire and psychological tests revealed they are common throughout adulthood. Of affected subjects 68% were female, and those with the more severe type (=3 Manning criteria) were-predominantly female (80%). Fewer Asians than other racial\\/ethnic groups had these symptoms. Nongastrointestinal symptoms, physician visits, incontinence, laxative use, a stress

George F. Longstreth; Girma Wolde-Tsadik

1993-01-01

359

Attention Deficit Hyperactivity Disorder Symptoms Mediate Early-Onset Smoking  

Microsoft Academic Search

Background\\/Aims: Symptoms of attention deficit hyperactivity disorder (ADHD) have often been associated with early-onset smoking. We hypothesize that reductions in ADHD symptoms due to an intervention have a mediating effect on early-onset smoking. Methods: In a universal, school-based, randomized controlled intervention trial, we examined whether intervention-induced reductions in ADHD symptoms at age 9 mediated the reduced risk of tobacco use

A. C. Huizink; P. A. C. van Lier; A. A. M. Crijnen

2009-01-01

360

Attention deficit hyperactivity disorder symptoms mediate early-onset smoking  

Microsoft Academic Search

Background\\/Aims: Symptoms of attention deficit hyperactivity disorder (ADHD) have often been associated with early-onset smoking. We hypothesize that reductions in ADHD symptoms due to an intervention have a mediating effect on early-onset smoking. Methods: In a universal, school-based, randomized controlled intervention trial, we examined whether intervention-induced reductions in ADHD symptoms at age 9 mediated the reduced risk of tobacco use

A. C. Huizink; Lier van P. A. C; A. A. M. Crijnen

2008-01-01

361

Children's and parents' daily stressful events and psychological symptoms  

Microsoft Academic Search

Associations of children's daily stressful events and their parents' daily hassles and psychological symptoms with children's emotional\\/behavioral problems were examined in a sample of fourth- and fifth-grade children and their parents. Correlational analyses indicated that children's self-reports of depressive symptoms were associated with children's daily stressors and mothers' daily hassles, and children's selfreports of anxiety symptoms were associated with children's

Gerard A. Banez; Bruce E. Compas

1990-01-01

362

Withdrawal symptoms after graduated cessation of imipramine in children.  

PubMed

In a systematic retrospective study the authors reviewed charts of 22 depressed children on a clinical research unit who were withdrawn from high-dose imipramine. Significant withdrawal symptoms were found over seven symptom categories despite an average tapering period of 6.4 days. These results suggest that withdrawal symptoms in children may be much more prevalent and intense than previously recognized. PMID:7235061

Law, W; Petti, T A; Kazdin, A E

1981-05-01

363

A twin study of autism symptoms in Sweden  

Microsoft Academic Search

This study aimed to identify empirically the number of factors underlying autism symptoms—social impairments, communication impairments, and restricted repetitive behaviors and interests—when assessed in a general population sample. It also investigated to what extent these autism symptoms are caused by the same or different genetic and environmental influences. Autistic symptoms were assessed in a population-based twin cohort of >12 000

A Ronald; H Larsson; H Anckarsäter; P Lichtenstein

2011-01-01

364

Modifiable factors associated with changes in postpartum depressive symptoms  

Microsoft Academic Search

Up to 50% of mothers report postpartum depressive symptoms yet providers do a poor job predicting and preventing their occurrence.\\u000a Our goal was to identify modifiable factors (situational triggers and buffers) associated with postpartum depressive symptoms.\\u000a Observational prospective cohort telephone study of 563 mothers interviewed at 2 weeks and 6 months postpartum. Mothers reported\\u000a on demographic factors, physical and emotional symptoms, daily

Elizabeth A. Howell; Pablo A. Mora; Marco D. DiBonaventura; Howard Leventhal

2009-01-01

365

DC-8-based observations of aircraft CO, CH4, N2O, and H2O(g) emission indices during SUCCESS  

NASA Astrophysics Data System (ADS)

We report the first measurements of CO, CH4, N2O, CO2, and H2O(g) in the exhaust trails of T-39, B-757, and DC-8 aircraft at cruise conditions. Emission indices (EI) derived from these in-situ measurements are presented. Results are in agreement with ground-based tests indicating aircraft act as a net sink for CH4 and recent airborne in-situ measurements that N2O is not an important exhaust constituent. Condensation of H2O(g) on exhaust particles resulted in EI(H2O(g)) values less than those expected from the combustion of fuel alone. Observed apparent negative EI(H2O(g)) values suggest that aircraft aerosol emissions, under unique atmospheric conditions, seed cloud formation and lead to dehydration of the exhaust-influenced air parcel. Such conditions may induce the formation of cirrus clouds from persistent contrails. Comparisons with the Boeing EMIT Code show measurement-derived CO emission index values consistent with model evaluations.

Vay, S. A.; Anderson, B. E.; Sachse, G. W.; Collins, J. E., Jr.; Podolske, J. R.; Twohy, C. H.; Gandrud, B.; Chan, K. R.; Baughcum, S. L.; Wallio, H. A.

366

Heterogeneous trajectories of depressive symptoms: Adolescent predictors and adult outcomes  

PubMed Central

Background Depressive symptoms display heterogeneous trajectories across adolescence and early adulthood. Identifying risk and protective factors for distinct trajectory groups, and their respective outcomes, may provide insight into the etiological underpinnings of different symptom courses and inform the targets and timing of intervention. Methods A school-based sample of 719 adolescents completed four diagnostic evaluations and up to 7 annually mailed questionnaires assessing psychiatric symptoms and psychosocial risk and protective factors. Parental history of psychiatric disorder was assessed. Growth mixture modeling (GMM) was used to identify latent depressive symptom trajectories from mid-adolescence through age 30, as well as their predictors in mid-adolescence and adult outcomes. Results A three class model consisting of high stable (32%), moderate decreasing (44%), and low decreasing (24%) depressive symptom trajectories emerged as the preferred solution. Demographic, psychosocial, and psychiatric characteristics differentiated the low and high symptom classes, and provided support for interpersonal models of depression chronicity. Members of the moderate and high symptom classes evidenced the worst psychosocial and psychiatric outcomes by age 30, with members of the high symptom class showing the greatest levels of impairment. Limitations Cross-sectional measurement and floor effects of several predictor variables may have obscured the relations between those predictors and trajectory class membership. Conclusion These findings suggest that prevention and intervention strategies may specifically target young women and those who experience poor interpersonal functioning in an effort to alter the course of depressive symptoms through early adulthood.

Yaroslavsky, Ilya; Pettit, Jeremy W.; Lewinsohn, Peter M.; Seeley, John R.; Roberts, Robert E.

2012-01-01

367

Modeling associations between posttraumatic stress symptoms and substance use.  

PubMed

Comorbid substance use and posttraumatic stress disorders (SUD-PTSD) predict poorer treatment outcomes. Self-medication has been forwarded as a symptom-level explanatory model. However, research has yet to be conducted that can provide detailed examination of SUD and PTSD symptom fluctuations over time as posited by such a process. This pilot study examined associations between PTSD and substance dependence (SD) symptoms/substance use using two established methodologies that assess week-by-week symptom and substance use/dependence status. Outpatients (N=35) in SUD treatment completed the Longitudinal Follow-Up Evaluation and the Time Lime Follow-Back Interview, retrospectively reporting weekly PTSD and SD symptoms, and substance use over the previous 6-months. Results indicated that weekly PTSD symptom fluctuations were concurrently associated with the presence of alcohol and cocaine dependence symptoms and were associated with the presence of opiate dependence symptoms in the following week. These findings support a self-medication conceptualization, underscore the utility of using a more detailed process analysis of PTSD and SD symptoms, and suggest that PTSD fluctuations are associated with substance problems, rather than with substance use per se. PMID:19729250

Ouimette, Paige; Read, Jennifer P; Wade, Michael; Tirone, Vanessa

2010-01-01

368

Emotion regulation predicts symptoms of depression over five years.  

PubMed

Deficits in emotion regulation have been identified as an important risk and maintaining factor for depression. The aim of this study was to examine the long-term effects of emotion regulation on symptoms of depression. Moreover, we investigated which specific emotion regulation skills were associated with subsequent symptoms of depression. Participants were 116 individuals (78% women, average age 35.2 years) who registered for an online-based assessment of depression and its risk-factors and reported at least some symptoms of depression. Successful application of emotion regulation skills and depressive symptom severity were assessed twice over a 5-year period. We utilized cross-lagged panel analyses to assess whether successful skills application would be negatively associated with subsequent depressive symptom severity. Cross-lagged panel analyses identified successful skills application as a significant predictor for depressive symptom severity even when controlling for the effects of initial symptoms of depression. A comparison of the effect sizes for different emotion regulation skills on subsequent depressive symptoms suggests that most of the skills included have similar predictive value. These findings provide preliminary evidence for the hypotheses that deficits in emotion regulation may contribute to the development of depression and that interventions systematically enhancing adaptive emotion regulation skills may help prevent and treat depressive symptoms. PMID:24754907

Berking, Matthias; Wirtz, Carolin M; Svaldi, Jennifer; Hofmann, Stefan G

2014-06-01

369

How religious doubt moderates depression symptoms following older adult bereavement.  

PubMed

This study examined the relationship of religious doubt with mental health following bereavement, using data from a nationally representative longitudinal survey of religion and health in older adulthood. Growth curve modeling analyzed trajectories of change in symptoms of depression at up to three waves over up to seven years following either family bereavement or non-bereavement trauma. After bereavement, those with more religious doubt reported worsening symptoms, whereas those with less doubt reported stable or improving symptoms over the same period. After nonbereavement trauma, religious doubt was not associated with symptom change. PMID:24524584

Hayward, R David; Krause, Neal

2014-04-01

370

Symptoms of autism among children with congenital deafblindness.  

PubMed

Associations between congenital deafness or blindness and autism have been found. The main consequences of congenital sensory impairment, being barriers for communication, language and social interaction development, may lead to symptoms of autism. To date only few studies have been reported concerning individuals with congenital deafblindness. This study examines symptoms of autism among 71 children with congenital deafblindness using the Autism Behavior Checklist. The cohort of children with congenital deafblindness was found to have symptoms of autism on a level similar to children with another developmental disorder than autism for example intellectual disability. No association was found between severity of congenital sensory impairment and severity or type of symptoms of autism. PMID:24127166

Dammeyer, Jesper

2014-05-01

371

Early menopause presenting with mood symptoms in a student aviator.  

PubMed

The clinical presentation of menopause can resemble the symptoms of a mood disorder. We describe the case of a 31-yr-old student helicopter pilot who presented to the Aviation Psychiatry Department with a several-month history of inconsistent training performance, mood lability, tearfulness, anxiety, insomnia, fatigue, and decreased concentration. Symptoms persisted despite stress management training and resolution of family stressors, and further evaluation revealed other symptoms consistent with early menopause. Symptoms responded to estrogen/progesterone therapy, and patient returned to flight training. The clinical presentation, differential diagnosis, treatment, and aeromedical disposition of perimenopause and menopause are discussed. PMID:10716170

Berg, J S; Moore, J

2000-03-01

372

The Impact of Residual Symptoms in Major Depression  

PubMed Central

The current definition of remission from major depressive disorder does not fully take into account all aspects of patient recovery. Residual symptoms of depression are very common in patients who are classified as being in remission. Patients with residual symptoms are at increased risk of functional and interpersonal impairments, and are at high risk for recurrence of depression. This article discusses the incidence of residual symptoms of depression, as well as the risks and consequences of these symptoms, and will review the state of current treatment.

Israel, Joshua A.

2010-01-01

373

Longitudinal associations between smoking and depressive symptoms among adolescent girls.  

PubMed

Adolescence is an important period for initiation of smoking and manifestation of depression, which are often comorbid. Researchers have examined associations between depressive symptoms and smoking to elucidate whether those with increased depressive symptoms smoke more to self-medicate, whether those who smoke experience increased subsequent depressive symptoms, or both. Collectively, there have been mixed findings; however, studies have been limited by (1) cross-sectional or short-term longitudinal data or (2) the use of methods that test associations, or only one direction in the associations, rather than a fully-reciprocal model to examine directionality. This study examined the associations between smoking and depressive symptoms in a sample of adolescent girls using latent dual change scores to model (1) the effect of smoking on change in depressive symptoms, and simultaneously (2) the effect of depressive symptoms on change in smoking across ages 11-20. Data were from a cohort-sequential prospective longitudinal study (N?=?262). Girls were enrolled by age cohort (11, 13, 15, and 17 years) and were primarily White (61 %) or African American (31 %). Data were restructured by age. Every 6 months, girls reported depressive symptoms and cigarette use. Results indicated that controlling for sociodemographic characteristics, higher levels of smoking predicted a greater increase in depressive symptoms across adolescence. These findings suggest that a higher level of cigarette smoking does contribute to more depressive symptoms, which has implications for prevention of depression and for intervention and future research. PMID:23689842

Beal, Sarah J; Negriff, Sonya; Dorn, Lorah D; Pabst, Stephanie; Schulenberg, John

2014-08-01

374

THE STABILITY OF SYMPTOMS AND SYNDROMES IN CHRONIC SCHIZOPHRENIC PATIENTS  

PubMed Central

36 chronic schizophrenic patients meeting D.S.M. III - R criteria were assessed by a single rater using the Positive and Negative Syndrome Scale (PANSS). Ratings were repeated 9 months later by the same rater. Negative symptoms and syndromes were much more stable over time than positive symptoms and syndromes. Only hallucinations had stability comparable to the negative symptoms. Positive and negative subtypes of schizophrenia based on the composite score were very stable. Relatively few symptoms from the general psychopathology subscale were stable over time. The implications of these findings are discussed.

Borde, Milind; Davis, Elizabeth J.B.; Sharma, L.N.

1992-01-01

375

Drag Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome  

PubMed Central

Drug rash with eosinophilia and systemic symptoms syndrome is a severe idiosyncratic drug reaction with a long latency period. It has been described using many terms; however, drug rash with eosinophilia and systemic symptoms syndrome appears to be the most appropriate. This syndrome causes a diverse array of clinical symptoms, anywhere from 2 to 8 weeks after initiating the offending drug. Standardized criteria for the diagnosis have been developed; however, their utility remains to be validated. Unfortunately, the management of drug rash with eosinophilia and systemic symptoms syndrome is not well supported by strong evidence-based data.

McLeod, Michael; Torchia, Daniele; Romanelli, Paolo

2013-01-01

376

Prevalence of GERD symptoms in a representative Israeli adult population.  

PubMed

The prevalence of gastroesophageal reflux disease (GERD) symptoms in the general population is lower in Asian than Western countries. Data are lacking for countries in the Middle East. The aim of the study was to determine the prevalence and severity of GERD symptoms among Israeli Jews. A questionnaire including 8 specific questions for GERD symptoms was administered by telephone interview to a representative sample of the population. One thousand two hundred twenty-one of 1839 individuals were successfully contacted and 981 had valid, complete data. The mean age was 45.0 years and 55% were females. Over the previous year 34.8% of the respondents reported suffering any GERD symptom. Of these 11.6% reported retrosternal burning, 11.7% retrosternal pain, 19.0% an acid taste in the mouth, and 17.5% reflux of gastric content. In all, 6.5%, 5.2%, 10.4%, and 7.9%, respectively, suffered these symptoms at least once a week, and 2.0%, 1.8%, 2.4%, and 2.3%, respectively, defined their symptoms as frequent and severe. Male sex (P=0.01) and a functional lower gastrointestinal (GI) disorder (P<0.0001) contributed significantly to the severity of upper GI reflux-like symptoms. In conclusion, GERD symptoms are common among Israeli Jews. The symptoms are generally of mild-to-moderate severity and are significantly associated with lower functional GI disorders. PMID:17450026

Sperber, Ami D; Halpern, Zamir; Shvartzman, Pesach; Friger, Michael; Freud, Tami; Neville, Anat; Fich, Alex

2007-01-01

377

Nonmotor Symptoms in a Malaysian Parkinson's Disease Population  

PubMed Central

Background. The nonmotor symptoms are important determinants of health and quality of life in Parkinson's disease but are not well recognized and addressed in clinical practice. This study was conducted to determine the prevalence of nonmotor symptoms and their impact on quality of life in patients with Parkinson's disease. Methods. This was a cross-sectional study among patients with idiopathic Parkinson's disease. Exclusion criteria were a Mini Mental State Examination score of <21/30. Prevalence of nonmotor symptoms was determined using the NMSQuest. The severity of nonmotor symptoms and the quality of life were assessed using validated disease-specific questionnaires (PDQ-39 and NMSS). Results. A total of 113 patients consisting of 60 males and 53 females were recruited. The median duration of illness was 5.0 (2.0–8.0) years. The prevalence rate of nonmotor symptoms in our cohort was 97.3%. The most common reported nonmotor symptom in our cohort was gastrointestinal (76.1%). We found that the severity of the nonmotor symptoms was associated with poorer quality of life scores (rs: 0.727, P < 0.001). Conclusions. Nonmotor symptoms were highly prevalent in our patients with Parkinson's disease and adversely affected the quality of life of our patients. In contrast to western studies, the most common nonmotor symptom is gastrointestinal. The possibility of an Asian diet playing a role in this observation requires further study.

Azmin, Shahrul; Khairul Anuar, Abdul Manaf; Tan, Hui Jan; Nafisah, Wan Yahya; Raymond, Azman Ali; Hanita, Othman; Shah, Shamsul Azhar; Norlinah, Mohamed Ibrahim

2014-01-01

378

Neuropsychiatric symptoms and interleukin-6 serum levels in acute stroke.  

PubMed

The role of interleukin-6 (IL-6) as a risk factor for developing depressive symptoms, neuropsychological impairment, and related functional and neurological symptom severity during the acute phase of ischemic stroke is still underexplored. Here, the authors assessed this issue, in 48 patients without significant clinical history for major medical illnesses or other factors that promote inflammation, 72 hours after a first-ever acute ischemic stroke. In the acute phase of ischemic stroke, increased IL-6 plays a key role in the onset of depressive disorders, apathy/amotivation, somatic symptoms of depression, and neurological/functional symptoms, resulting in higher disability and poor outcome of stroke patients. PMID:24247852

Spalletta, Gianfranco; Cravello, Luca; Imperiale, Francesca; Salani, Francesca; Bossù, Paola; Picchetto, Livio; Cao, Marina; Rasura, Maurizia; Pazzelli, Floriana; Orzi, Francesco; Caltagirone, Carlo; Robinson, Robert G; Cacciari, Claudia

2013-01-01

379

Causes, symptoms and prevention of food allergy  

PubMed Central

Currently, food allergy is considered to be one of the diseases of civilization, which occurs as a result of the changing conditions of life and environmental changes (e.g. increased popularity of cesarean delivery, excessive hygienic regime during the neonatal-infantile period). Based on medical statistics, it can be concluded that this problem will be intensified. Consumption of food is one of the main activities in human life. What and how one eats affects our health. Meals eaten regularly provide the components necessary for the energy metabolism. Multicultural society, travel, and new trends affect the diversity of food consumed. The mechanism of food allergy reaction covers all 4 types of the immune response of the classical division of Gell and Coombs. The percentage of the immune response was assessed by Chandra as follows: type I – 48%, type II – 6%, type III – 10%, and type IV – 18%. The article presents the risk factors for food allergy, most common symptoms, preventive measures and characteristics of food products that are potential allergens.

Wroblewska, Paula; Adamczuk, Piotr; Kopczynski, Przemyslaw

2013-01-01

380

Causes, symptoms and prevention of food allergy.  

PubMed

Currently, food allergy is considered to be one of the diseases of civilization, which occurs as a result of the changing conditions of life and environmental changes (e.g. increased popularity of cesarean delivery, excessive hygienic regime during the neonatal-infantile period). Based on medical statistics, it can be concluded that this problem will be intensified. Consumption of food is one of the main activities in human life. What and how one eats affects our health. Meals eaten regularly provide the components necessary for the energy metabolism. Multicultural society, travel, and new trends affect the diversity of food consumed. The mechanism of food allergy reaction covers all 4 types of the immune response of the classical division of Gell and Coombs. The percentage of the immune response was assessed by Chandra as follows: type I - 48%, type II - 6%, type III - 10%, and type IV - 18%. The article presents the risk factors for food allergy, most common symptoms, preventive measures and characteristics of food products that are potential allergens. PMID:24278058

Zukiewicz-Sobczak, Wioletta Agnieszka; Wróblewska, Paula; Adamczuk, Piotr; Kopczy?ski, Przemys?aw

2013-04-01

381

Symptom management and psychosocial outcomes following cancer.  

PubMed

Transition from the completion of cancer treatment to post-treatment is a pivotal first step in survivorship. Following the end of treatment patients may experience lingering symptoms, compromised physical function, and emotional distress. Within the larger survivorship literature less attention has been devoted to this immediate post acute treatment period. To organize this review a post-treatment risk model is presented; it is informed by the emotional health and comorbid conditions patients bring to their treatment. When integrated with the aggressiveness of treatment(s), the side effects experienced, and emotional responses, this profile defines and characterizes patients' post-treatment needs. Some patients need little more than a standard survivorship care plan with clearly defined shared care responsibilities for the oncologist and primary care physician. Others need more and varied forms of assistance. This review documents the range of physical and psychosocial problems patients' face as they transition from active treatment to survivorship. We conclude with suggestions for future research tailored to patient's post-treatment needs for care. PMID:24331196

Given, Charles W; Given, Barbara A

2013-12-01

382

Ubiquinol Improves Symptoms in Children with Autism  

PubMed Central

Background. Autism is a spectrum of neurodevelopmental disorders with manifestation within 3 years after birth. Manifestations of autism include behavior problems (hyperactivity, toys destruction, self-harm, and agression) and sleep and eating disorders. Etiology of autism is poorly understood. Oxidative stress and antioxidants can participate in pathobiochemical mechanisms of autism. Methods. Twenty-four children, aged 3–6 years, with autism according to the DSM IV criteria and using CARS were included in the study. Concentrations of CoQ10?TOTAL, ?- and ?-tocopherol, ?-carotene, and lipid peroxidation were determined in plasma before and after three months of supportive therapy with ubiquinol at a daily dose 2 × 50?mg. Data on behavior of the children were collected from parents at the same time. Results. Ubiquinol supportive therapy improved symptoms in children with autism, as communication with parents (in 12%), verbal communication (in 21%), playing games of children (in 42%), sleeping (in 34%), and food rejection (in 17%), with CoQ10?TOTAL plasma level above 2.5??mol/L. Conclusions. Beneficial effect of ubiquinol in children with autism has been demonstrated for the first time. We assume that plasma concentration of CoQ10?TOTAL and lipid peroxidation could be used as relevant biomarkers of ubiquinol supportive therapy.

Kucharska, Jarmila; Ostatnikova, Daniela; Babinska, Katarina; Nakladal, Dalibor; Crane, Fred L.

2014-01-01

383

Obsessive-compulsive symptoms in Parkinson's disease  

PubMed Central

To systematically investigate obsessive-compulsive traits in Parkinson's disease, patients were administered the Maudsley obsessional-compulsive inventory (MOCI) and a modification of the Leyton obsessional inventory (LOI) to a sample of non-demented and non-depressed patients with Parkinson's disease. Patients with severe Parkinson's disease showed more obsessive traits than normal controls in MOCI and LOI total scores, and in the "checking", "doubting", and "cleaning" subscales of the MOCI. By contrast, patients with mild disease did not differ from controls. A significant correlation was found between severity and duration of illness and MOCI total score. These results support the involvement of basal ganglia in obsessive-compulsive symptomatology. As patients with mild Parkinson's disease did not differ from controls, obsessive-compulsive disorder does not seem to be directly related to the initial nigrostriatal dopaminergic deficiency which causes clinical Parkinson's disease symptomatology. The appearance of obsessive symptoms could be related to the subset of neurochemical changes taking place at the level of the basal ganglia circuitry as disease progresses.??

Alegret, M; Junque, C; Valldeoriola, F; Vendrell, P; Marti, M; Tolosa, E

2001-01-01

384

Obsessive-compulsive symptoms in Parkinson's disease.  

PubMed

To systematically investigate obsessive-compulsive traits in Parkinson's disease, patients were administered the Maudsley obsessional-compulsive inventory (MOCI) and a modification of the Leyton obsessional inventory (LOI) to a sample of non-demented and non-depressed patients with Parkinson's disease. Patients with severe Parkinson's disease showed more obsessive traits than normal controls in MOCI and LOI total scores, and in the "checking", "doubting", and "cleaning" subscales of the MOCI. By contrast, patients with mild disease did not differ from controls. A significant correlation was found between severity and duration of illness and MOCI total score. These results support the involvement of basal ganglia in obsessive-compulsive symptomatology. As patients with mild Parkinson's disease did not differ from controls, obsessive-compulsive disorder does not seem to be directly related to the initial nigrostriatal dopaminergic deficiency which causes clinical Parkinson's disease symptomatology. The appearance of obsessive symptoms could be related to the subset of neurochemical changes taking place at the level of the basal ganglia circuitry as disease progresses. PMID:11181867

Alegret, M; Junqué, C; Valldeoriola, F; Vendrell, P; Martí, M J; Tolosa, E

2001-03-01

385

Treatment of oral symptoms in Sjögren's syndrome.  

PubMed

The most pronounced oral symptoms in Sjögren's syndrome are a dry sensation of the mouth and difficulties in swallowing and speech. Besides these patients do no sleep well and may complain about burning mucous membranes, rampant caries and candidosis. Rampant caries can be prevented by optimal oral hygiene and frequent applications of a neural 1% sodium fluoride gel. Prophylaxis of candidosis can be obtained by meticulous oral hygiene and removal of predisposing factors (e.g. poor dentures). For the other oral signs of Sjögren's syndrome only a symptomatic treatment is possible, because damage of salivary gland tissue is progressive and irreversible. Good results can be obtained by applying a mucin-containing saliva substitute, which has been shown to reduce the dry an burning sensation of the mouth as well as to improve chewing, swallowing, speech and sleeping. When applied by an atomizer it wets the oral cavity for about 30 min. A continuous wetting can be obtained using intra-oral artificial saliva reservoirs. PMID:3473643

Vissink, A; Panders, A K; Gravenmade, E J; Vermey, A

1986-01-01

386

Lymphoedema 2: classification, signs, symptoms and diagnosis.  

PubMed

The second article in this series describes the different types of lymphoedema and the signs and symptoms associated with the condition. In the preceding article (Vol 11(5): 304-9) we examined the anatomy, physiology and functions of the lympathic system in relation to the condition of lymphoedema, and demonstrated how, by acting as a one-way drainage system, the lympathics maintain tissue homeostasis through the removal of excess fluid from the interstitial spaces. Failure or dysfunction of the system can result in lymphoedema, a condition characterized by the accumulation of fluid in the soft tissues. Lymphoedema is classified into two main groups - primary and secondary. Defining the causative factors and pathogenesis of both conditions and other forms of chronic oedema will assist the reader in the clarification of the condition. The article concludes with an overview of assessment criteria for diagnosis, which should assist all healthcare professionals in appropriate referral. The third article in this series will look at the treatment of lymphoedema. PMID:11979219

Board, Jane; Harlow, Wendy

387

Birth order effects on autism symptom domains.  

PubMed

Autism is predominantly genetically determined. Evidence supports familiality of the main sets of behavioral characteristics that define the syndrome of autism; however, possible non-genetic effects have also been suggested. The present study compared levels of autism symptom domains, as measured by the Autism Diagnostic Interview, and useful phrase speech scores between 106 pairs of first- and second-born siblings from multiply affected families. In addition, the intercorrelations between the measures were compared between siblings. The overall mean repetitive behavior total score was significantly higher (worse) in first-born than in second-born siblings. In contrast, first-born siblings had significantly lower (better) useful phrase speech than their younger siblings. Autism social and non-verbal communication scores were significantly correlated in first- and in second-born siblings. However, there was a significant difference in the coefficients between first- and second-born siblings. Performance on the non-verbal communication domain was also significantly and positively correlated with useful phrase speech score in both first- and second-born siblings. It is unclear at this time whether these results are of biologic origin. Nevertheless, the findings suggest that genetic studies in autism using specific levels of familial autism traits as phenotypes should take into account their intercorrelations and birth order effects embedded in the instrument. PMID:17289158

Reichenberg, Abraham; Smith, Christopher; Schmeidler, James; Silverman, Jeremy M

2007-03-30

388

Toward the Next Generation of Negative Symptom Assessments: The Collaboration to Advance Negative Symptom Assessment in Schizophrenia  

PubMed Central

Negative symptoms in schizophrenia are related to poor functional outcome, persistent over time, a source of burden for caregivers, and only minimally responsive to currently available medications. A major challenge to developing efficacious interventions concerns the valid and reliable assessment of negative symptoms. In a recent consensus statement on negative symptoms, a central recommendation was the need to develop new assessment approaches that address the limitations of existing instruments. In the current report, we summarize the background and rationale for the Collaboration to Advance Negative Symptom Assessment in Schizophrenia (CANSAS). The CANSAS project is an National Institute of Mental Health-funded multisite study that is constructing a next-generation negative symptom scale, the Clinical Assessment Interview for Negative Symptoms (CAINS). The CAINS is being developed within a data-driven iterative process that seeks to ensure the measure’s reliability, validity, and utility for both basic psychopathology and treatment development research.

Blanchard, Jack J.; Kring, Ann M.; Horan, William P.; Gur, Raquel

2011-01-01

389

The development of the Chemotherapy Symptom Assessment Scale (C-SAS): a scale for the routine clinical assessment of the symptom experiences of patients receiving cytotoxic chemotherapy  

Microsoft Academic Search

The management of symptoms experienced by patients receiving cytotoxic chemotherapy influences quality of life during treatment. Symptom management may be improved through a structured approach to symptom assessment. This paper describes the development of the Chemotherapy Symptom Assessment Scale (C-SAS), a 24-item scale designed for the routine assessment of symptoms experienced by patients receiving cytotoxic chemotherapy. The scale development process

Vivienne Brown; John Sitzia; Alison Richardson; Jayne Hughes; Helen Hannon; Catherine Oakley

2001-01-01

390

Postcholecystectomy symptoms. A prospective study of gall stone patients before and two years after surgery.  

PubMed

The results of cholecystectomy in terms of symptomatic improvement were prospectively evaluated in 124 unselected gall stone patients interviewed before and two years after elective surgery. Indications for cholecystectomy were biliary pain (n = 65), previous complications of gall stone disease (n = 52), and flatulent dyspepsia (n = 7). At two years 93 patients could be re-evaluated, of whom only 49 (53%) were completely symptom free. Postcholecystectomy symptoms occurring in the remaining 44 patients were mainly flatulent dyspepsia (which had relapsed in 22 of 46 patients who suffered it preoperatively), dull abdominal pain or diarrhoea. Incisional hernia was present in five patients and one had recurrence of pain because of retained common bile duct stones. Symptomatic cures after cholecystectomy decreased with the duration of the preoperative history. The results reconfirm that cholecystectomy eradicates specific symptoms and complications of gall stone disease, but they also show that nearly one half of operated patients are dissatisfied with the procedure because of mild but distressing 'postcholecystectomy' symptoms. These are probably caused by previously undiagnosed functional gut disease associated with, but unrelated to, gall stones. A systemic approach to multisymptomatic patients with gall stones is recommended. PMID:3428678

Ros, E; Zambon, D

1987-11-01

391

An analysis of pure blowout fractures and associated ocular symptoms.  

PubMed

Blowout fractures are one of the commonly occurring facial bone fractures and clinically important, as they may cause serious complications such as diplopia, extraocular movement limitation, and enophthalmos. The purpose of this study was to evaluate the current patient demographics and surgical outcomes of 952 pure blowout fractures from 2 hospitals of the Catholic University of Korea, from 2003 to 2011. The medical records were reviewed according to the cause, fracture site, ocular symptoms, time of operation, and sequela. Male patients outnumbered female patients, and blowout fractures were most often seen in 21- to 30-year-old men. The most common cause was violent assault (40.7%). The medial orbital wall (45.8%) was the most common site, followed by floor (29.4%) and inferomedial wall (24.6%). The most common ocular injury was hyphema. Diplopia was presented in 27.6%; extraocular movement limitation was detected in 12.8% patients, and enophthalmos was encountered in 3.4% patients. Diplopia, extraocular movement limitation, and enophthalmos were significantly improved by surgical repair (P < 0.05). Postoperative complications were persistent diplopia (1.6%) and enophthalmos (0.4%). We surveyed a large series of blowout fracture in the Republic of Korea and recommend this study to serve as an important guideline in treating pure blowout fractures. PMID:23714863

Shin, Jun Woo; Lim, Jin Soo; Yoo, Gyeol; Byeon, Jun Hee

2013-05-01

392

Operations automation  

NASA Technical Reports Server (NTRS)

This is truly the era of 'faster-better-cheaper' at the National Aeronautics and Space Administration/Jet Propulsion Laboratory (NASA/JPL). To continue JPL's primary mission of building and operating interplanetary spacecraft, all possible avenues are being explored in the search for better value for each dollar spent. A significant cost factor in any mission is the amount of manpower required to receive, decode, decommutate, and distribute spacecraft engineering and experiment data. The replacement of the many mission-unique data systems with the single Advanced Multimission Operations System (AMMOS) has already allowed for some manpower reduction. Now, we find that further economies are made possible by drastically reducing the number of human interventions required to perform the setup, data saving, station handover, processed data loading, and tear down activities that are associated with each spacecraft tracking pass. We have recently adapted three public domain tools to the AMMOS system which allow common elements to be scheduled and initialized without the normal human intervention. This is accomplished with a stored weekly event schedule. The manual entries and specialized scripts which had to be provided just prior to and during a pass are now triggered by the schedule to perform the functions unique to the upcoming pass. This combination of public domain software and the AMMOS system has been run in parallel with the flight operation in an online testing phase for six months. With this methodology, a savings of 11 man-years per year is projected with no increase in data loss or project risk. There are even greater savings to be gained as we learn other uses for this configuration.

Boreham, Charles Thomas

1994-01-01

393

Symptoms After Hospital Discharge Following Hematopoietic Stem Cell Transplantation  

PubMed Central

Aims: The purposes of this study were to assess the symptoms of hematopoietic stem cell transplant patients after hospital discharge, and to determine the needs of transplant patients for symptom management. Materials and Methods: The study adopted a descriptive design. The study sample comprised of 66 hematopoietic stem cell transplant patients. The study was conducted in Istanbul. Data were collected using Patient Information Form and Memorial Symptom Assessment Scale (MSAS). Results: The frequency of psychological symptoms in hematopoietic stem cell transplant patients after discharge period (PSYCH subscale score 2.11 (standard deviation (SD) = 0.69, range: 0.93-3.80)) was higher in hematopoietic stem cell transplant patients than frequency of physical symptoms (PHYS subscale score: 1.59 (SD = 0.49, range: 1.00-3.38)). Symptom distress caused by psychological and physical symptoms were at moderate level (mean = 1.91, SD = 0.60, range: 0.95-3.63) and most distressing symptoms were problems with sexual interest or activity, difficulty sleeping, and diarrhea. Patients who did not have an additional chronic disease obtained higher MSAS scores. University graduates obtained higher Global Distress Index (GDI) subscale and total MSAS scores with comparison to primary school graduates. Total MSAS, MSAS-PHYS subscale, and MSAS-PSYCH subscale scores were higher in patients with low level of income (P < 0.05). The patients (98.5%) reported to receive education about symptom management after hospital discharge. Conclusions: Hematopoietic stem cell transplant patients continue to experience many distressing physical or psychological symptoms after discharge and need to be supported and educated for the symptom management.

Oguz, Gamze; Akin, Semiha; Durna, Zehra

2014-01-01

394

Modifiable factors associated with changes in postpartum depressive symptoms.  

PubMed

Up to 50% of mothers report postpartum depressive symptoms yet providers do a poor job predicting and preventing their occurrence. Our goal was to identify modifiable factors (situational triggers and buffers) associated with postpartum depressive symptoms. Observational prospective cohort telephone study of 563 mothers interviewed at 2 weeks and 6 months postpartum. Mothers reported on demographic factors, physical and emotional symptoms, daily function, infant behaviors, social support, and skills in managing infant and household. Mothers were categorized into four groups based on the presence of depressive symptoms at 2 weeks and at 6 months postpartum: never, always, late onset, and remission groups. Fifty-two percent did not have depressive symptoms at 2 weeks or at 6 months (never group), 14% had symptoms at both time points (always group), 10% had late onset, and 24% had early onset of symptoms with remission. As compared with women in the never group, women in the always and late onset groups had high-risk characteristics (e.g., past history of depression), more situational triggers (e.g., physical symptoms), and less robust social and personal buffers (i.e., social support and self-efficacy). As compared with the never group, mothers in the remission group had more situational triggers and fewer buffers initially. Changes in situational triggers and buffers were different for the four groups and were correlated with group membership. Situational triggers such as physical symptoms and infant colic, and low levels of social support and self-efficacy in managing situational demands are associated with postpartum depressive symptoms. Further research is needed to investigate whether providing education about the physical consequences of childbirth, providing social support, and teaching skills to enhance self-efficacy will reduce the incidence of postpartum symptoms of depression. PMID:19238520

Howell, Elizabeth A; Mora, Pablo A; DiBonaventura, Marco D; Leventhal, Howard

2009-04-01

395

Association of preoperative symptom profile with psychiatric symptoms following subthalamic nucleus stimulation in patients with Parkinson's disease.  

PubMed

In order to evaluate the severity of behavioral complications after deep brain stimulation of the subthalamic nucleus (STN-DBS) for Parkinson's disease and to explore possible predictive factors, the authors evaluated 22 patients for pre- and postoperative symptoms using a neurobehavioral battery. Compared to the time before STN-DBS, several behavioral symptoms had worsened in terms of prevalence and severity and appeared de novo in other patients. Apathy, anxiety, and suicidal ideation increased significantly, while depressive symptoms appeared stable. Compared with patients who improved, patients who had deteriorated behaviorally had similar prevalence and severity of preoperative behavioral symptoms but significantly shorter disease duration. PMID:19996248

Porat, Omer; Cohen, Oren S; Schwartz, Roseline; Hassin-Baer, Sharon

2009-01-01

396

Nightmares: from anxiety symptom to sleep disorder.  

PubMed

The DSM-IV-TR definition of nightmares-extremely frightening dreams from which the person wakes up directly-is unnecessarily narrow. Other emotions (anger, grief) have also been reported in nightmares, and direct awakening from a bad dream seems to be unrelated to increased distress. In addition, assessment of nightmares is problematic. Polysomnographic recordings have an ameliorating effect on nightmare frequency, retrospective measurements tend to underestimate nightmare frequency, and persons with frequent nightmares may feel reluctant to fill out (daily) prospective measurements. For studying nightmares, it is necessary to distinguish idiopathic nightmares from posttraumatic nightmares, which are part of a posttraumatic stress reaction or disorder that may result from experiencing a traumatic event. Both types of nightmares have been associated with an elevated level of periodic limb movements, although only posttraumatic nightmares seem to be related to more and longer nocturnal awakenings. Nightmares have also been repeatedly associated with the general level of psychopathology, or the so-called personality factor neuroticism. Nightmare distress, the impact on daily functioning caused by nightmares, may function as a mediating variable. Several studies in the last decades have shown that nightmares can be treated with several cognitive-behavioral techniques. The cognitive-restructuring technique imagery rehearsal therapy is the treatment of choice for nightmares, although a randomized controlled trial with an attention control-group has not yet been carried out. Nightmares are more than a symptom of a larger (anxiety) syndrome and need to be viewed from a sleep medicine perspective: nightmares are a highly prevalent and separate sleep disorder that can and should receive specific treatment. PMID:16377217

Spoormaker, Victor I; Schredl, Michael; van den Bout, Jan

2006-02-01

397

The Significance of the Symptoms Associated with Bladder Outflow Obstruction  

Microsoft Academic Search

The symptomatology and urodynamic findings of 318 male patients (45–84 years) with suspected bladder outflow obstruction have been analysed. Inflow cystometry showed that 57% of patients had unstable bladders and a pressure flow analysis of micturition that 67% had obstructed micturition. The symptoms of urgency, urge incontinence and frequency were associated with bladder instability and not with obstruction. The symptoms

Paul H. Abrams; Roger C. L. Feneley

1978-01-01

398

Increased incidence of depressive symptoms in men with erectile dysfunction  

Microsoft Academic Search

Objectives. To investigate the hypothesis that men with erectile dysfunction (ED) have a higher incidence of depressive symptoms compared with age-matched control subjects. We also hypothesized that depressive symptoms impact on the level of libido and on the success of treatment of ED.Methods. One hundred twenty men with ED or benign prostatic hyperplasia (BPH) were divided into three groups. Group

Ridwan Shabsigh; Lonnie T Klein; Stuart Seidman; Steven A Kaplan; Bernard J Lehrhoff; Joseph S Ritter

1998-01-01

399

Changes in Parental Depression Symptoms during Family Preservation Services  

ERIC Educational Resources Information Center

Objectives: Parental depression symptoms often change over the course of child welfare family preservation and parenting services. This raises the question of whether certain processes in family preservation services might be associated with depression symptom change. This study tests three correlational models of change among family preservation…

Chaffin, Mark; Bard, David

2011-01-01

400

Gulf War Illness: Lessons from medically unexplained symptoms  

Microsoft Academic Search

Service in the Persian Gulf in 1991 is associated with increased reporting of symptoms and distress in a proportion of those who served there. Yet despite clear evidence of an increase in symptom burden and a decrease in well being, exhaustive clinical and laboratory based scientific research has failed to document many reproducible biomedical abnormalities in this group. Likewise, there

Amy Iversen; Trudie Chalder; Simon Wessely

2007-01-01

401

ANALYSIS OF RELATIONSHIPS BETWEEN SYMPTOMS AND ENVIRONMENTAL FACTORS OVER TIME  

EPA Science Inventory

Weekly respiratory symptom information was obtained on a random population of 3800 whites in Tucson. The authors asked weekly about 14 symptoms representing acute respiratory illnesses (ARI), rhinitis (Rh), and other conditions. The denominator for each week was about 80 randomly...

402

Trajectories of depressive symptoms during emerging adulthood: Antecedents and consequences  

Microsoft Academic Search

In order to examine what kinds of trajectories of depressive symptoms young adults show during emerging adulthood, and their antecedents and consequences, 297 university students completed the revised Beck's depression inventory seven times over a 10-year period, and other measures at the beginning and the end of the study. The growth mixture modelling for depressive symptoms ended up in a

Katariina Salmela-Aro; Kaisa Aunola; Jari-Erik Nurmi

2008-01-01

403

A survey of psychosis risk symptoms in Kenya  

Microsoft Academic Search

Defining the prepsychotic state in an effort to prevent illness progression and the development of disorders such as schizophrenia is a rapidly growing area of psychiatry. The presentation of psychotic symptoms can be influenced by culture; however, there has not been any previous assessment of psychosis risk symptoms in the continent of Africa. Our study aimed to measure the prevalence

Daniel Mamah; Anne Mbwayo; Victoria Mutiso; Deanna M. Barch; John N. Constantino; Thelma Nsofor; Lincoln Khasakhala; David M. Ndetei

404

Schizotypal personality disorder or prodromal symptoms of schizophrenia?  

Microsoft Academic Search

Schizotypal personality disorder shares some attenuated phenotypic features with schizophrenia, but represents an independent syndrome. In contrast, prodromal symptoms of schizophrenia represent early warning signs of the impending onset of schizophrenia. Although these constructs are intended to reflect independent syndromes, self-report instruments measuring these constructs assess similar symptoms. It does not appear that existing research has examined the relative discriminant

Jeffrey S. Bedwell; Reesa S. Donnelly

2005-01-01

405

Symptom interval in young people with bone cancer  

Microsoft Academic Search

Symptom interval (SI), the time from first symptom\\/sign to diagnosis and initiation of treatment, appears to be principally influenced by tumour biology. Whether the age of the patient, patient delay, professional delay and access to health professionals influences the SI in bone tumours was investigated in this study.115 patients with newly diagnosed osteosarcoma and Ewing's sarcoma were retrospectively reviewed. The

S. Goyal; J. Roscoe; W. D. J. Ryder; H. R. Gattamaneni; T. O. B. Eden

2004-01-01

406

The relationship between borderline personality disorder criteria and dysthymia symptoms  

Microsoft Academic Search

Several authors have proposed that the comorbidity of borderline personality disorder is, in part, due to the overlap between the criterion sets. To test this proposition, the relationship between BPD criteria and dysthymia symptoms was assessed in a large sample of psychiatric inpatients. Substantial covariation was observed between individual BPD items and dysthymia symptoms. In addition, results indicated that four

Timothy J. TrullL; Thomas A. Widiger

1991-01-01

407

Trauma Symptoms and Life Skill Needs of Domestic Violence Victims  

ERIC Educational Resources Information Center

This study identified the trauma symptoms and life skill needs of 84 domestic violence victims from three domestic violence programs. Women completed two self-report tools: Trauma Symptom Inventory (TSI) and Occupational Self Assessment (OSA). Staff members participated in focus groups regarding their perceptions of the womens needs. Women scored…

Gorde, Mrugaya W.; Helfrich, Christine A.; Finlayson, Marcia L.

2004-01-01

408

Prediction of posttraumatic stress symptoms in children after Hurricane Andrew  

Microsoft Academic Search

The authors used an integrative conceptual model to examine the emergence of posttraumatic stress disorder (PTSD) symptoms in 568 elementary school-age children 3 months after Hurricane An- drew. The model included 4 primary factors: Exposure to Traumatic Events, Child Characteristics, Access to Social Support, and Children's Coping. Overall, 62% of the variance in children's self- reported PTSD symptoms was accounted

Eric M. Vernberg; Annette M. La Greca; Wendy K. Silverman; Mitchell J. Prinstein

1996-01-01

409

Preliminary report: Symptoms associated with mobile phone use  

Microsoft Academic Search

Mobile phone use is ubiquitous, although the alleged health effects of low level radio-frequency radiation (RFR) used in transmission are contentious. Following isolated reports of headache-like symptoms arising in some users, a survey has been conducted to characterize the symptoms sometimes associated with mobile phone usage. A notice of interest in cases was placed in a major medical journal and

B. Hocking

1998-01-01

410

Genetic and Environmental Effects on Vocal Symptoms and Their Intercorrelations  

ERIC Educational Resources Information Center

Purpose: Recently, Simberg et al. (2009) found genetic effects on a composite variable consisting of 6 vocal symptom items measuring dysphonia. The purpose of the present study was to determine genetic and environmental effects on the individual vocal symptoms in a population-based sample of Finnish twins. Method: The sample comprised 1,728 twins…

Nybacka, Ida; Simberg, Susanna; Santtila, Pekka; Sala, Eeva; Sandnabba, N. Kenneth

2012-01-01

411

Maternal and Paternal Depressive Symptoms as Predictors of Toddler Adjustment  

ERIC Educational Resources Information Center

In this study we explored the relation between maternal and paternal depressive symptoms and toddler adjustment in a community sample, testing direct, additive, and interactive models of parental depressive symptoms and child adjustment. Participants were 49 families with 30-month-old children. Data were collected on maternal and paternal…

Weinfield, Nancy S.; Ingerski, Lisa; Moreau, Stacey Coffey

2009-01-01

412

Ethnic Differences in Symptom Presentation of Sexually Abused Girls  

ERIC Educational Resources Information Center

Although researchers have begun to examine the issue of ethnic and cultural factors in childhood sexual abuse (CSA), relatively little has been done to look at possible ethnic and cultural differences in psychological symptoms related to CSA. This study investigated the relationship between ethnicity and symptom presentation among Hispanic,…

Clear, Paul J.; Vincent, John P.; Harris, Gerald E.

2006-01-01

413

Negative symptoms in schizophrenia: considerations for clinical trials  

Microsoft Academic Search

There is little agreement about the methodology of clinical trials of antipsychotic drugs in patients with negative symptoms. A literature review revealed wide variation in experimental design, rating scales and study duration. This reflects differing views as to the definition and response to treatment of negative symptoms. Some degree of standardization would improve comparability of studies and aid the development

H.-J. Möller; H. M. Praag; B. Aufdembrinke; P. Bailey; T. R. E. Barnes; J. Beck; H. Bentsen; F. X. Eich; L. Farrow; W. W. Fleischhacker; J. Gerlach; K. Grafford; B. Hentschel; A. Hertkorn; S. Heylen; Y. Lecrubier; J. P. Leonard; P. McKenna; W. Maier; V. Pedersen; A. Rappard; W. Rein; J. Ryan; M. Sloth Nielsen; R.-D. Stieglitz; G. Wegener; J. Wilson

1994-01-01

414

Gastrointestinal symptoms in a Japanese population: A health diary study  

PubMed Central

AIM: To investigate the incidence of gastrointestinal symptoms and the nature of consequent utilization of health care services in a Japanese population. METHODS: Using self-report, we conducted a prospective cohort study of a nationally representative sample of the Japanese population over a one-month period to determine the incidence of gastrointestinal symptoms of all kinds and resultant health care utilization. Both information on visits to physicians and use of complementary and alternative medicine therapies were collected. RESULTS: From a total of 3568 in the recruitment sample, 3477 participants completed a health diary (response rate 97%). The data of 112 participants with baseline active gastrointestinal diseases were excluded from the analysis, leaving 3365 participants in the study. The incidence of gastrointestinal symptoms was 25% and the mean number of symptomatic episodes was 0.66 in a month. Abdominal pain, diarrhea, nausea, constipation and dyspepsia were the most frequent symptoms. Female gender, younger age, and low baseline quality of life were risk factors for developing these symptoms. The participants were more likely to treat themselves, using dietary, complementary or alternative medicines, than to visit physicians, except in the case of vomiting. CONCLUSION: Gastrointestinal symptoms are common in the Japanese population, with an incidence of 25%. Abdominal pain, diarrhea, nausea, constipation and dyspepsia are the most frequent symptoms. Risk factors for developing these symptoms include female gender, younger age, and low baseline quality of life.

Tokuda, Yasuharu; Takahashi, Osamu; Ohde, Sachiko; Shakudo, Masaaki; Yanai, Haruo; Shimbo, Takuro; Fukuhara, Shunichi; Hinohara, Shigeaki; Fukui, Tsuguya

2007-01-01

415

Methamphetamine use and depressive symptoms among heterosexual men and women  

Microsoft Academic Search

This study investigated the relationship between intensity of methamphetamine use and depressive symptoms in a sample of 182 heterosexually identified methamphetamine users. Perceived stigma and social and health problems were hypothesized as potential mediators of the relationship between methamphetamine use and depressive symptoms. Forty per cent of the sample met criteria for moderate to severe depression. As hypothesized, the greater

Shirley J. Semple; Thomas L. Patterson; Igor Rant

2005-01-01

416

Stress, Negative Social Exchange, and Health Symptoms in University Students.  

ERIC Educational Resources Information Center

Examined the contributions of positive social support and negative social exchange in the relationship between stress and health symptoms. College student surveys indicated that negative social exchange significantly predicted physical symptoms, while positive social support did not. The relationship between negative social interaction and…

Edwards, Kevin J.; Hershberger, Paul J.; Russell, Richard K.; Markert, Ronald J.

2001-01-01

417

Mindfulness-based cognitive therapy for residual depressive symptoms  

Microsoft Academic Search

Objectives. Mindfulness-based cognitive therapy (MBCT) is a new group-based intervention for prevention of relapse in recurrent depression which has not been scientifically evaluated regarding its clinical effectiveness for ameliorating residual depressive symptoms following a depressive episode. The aim of this study was to assess the efficacy of MBCT in reducing residual depressive symptoms in psychiatric outpatients with recurrent depression, and

Tara Kingston; Barbara Dooley; Anthony Bates; Elizabeth Lawlor; Kevin Malone

2007-01-01

418

Sleep Deprivation, Allergy Symptoms, and Negatively Reinforced Problem Behavior.  

ERIC Educational Resources Information Center

A study of the relationship between presence or absence of sleep deprivation, allergy symptoms, and the rate and function of problem behavior in three adolescents with moderate to profound mental retardation found that problem behavior was negatively reinforced by escape from instruction, and both allergy symptoms and sleep deprivation influenced…

Kennedy, Craig H.; Meyer, Kim A.

1996-01-01

419

Symptoms of ADHD and Close Friendships in Adolescence  

ERIC Educational Resources Information Center

Objective: This study examined the relationship of ADHD symptoms to different aspects of close friendship quality as rated by both adolescents (target adolescent and a close friend) within a friendship dyad. Method: Participants were 41 same-sex friendship dyads who completed questionnaires about their friendship. Separate symptom dimensions of…

Glass, Kerrie; Flory, Kate; Hankin, Benjamin L.

2012-01-01

420

Male lower urinary tract symptoms associated with overactive bladder  

PubMed Central

Lower urinary tract symptoms (LUTS) associated with overactive bladder (OAB) are more likely to respond to antimuscarinic therapy than to alpha blockade. As such, initial treatment of men with storage symptoms should incorporate an antimuscarinic agent. For men who are truly refractory to current pharmacotherapies, there is emerging evidence to support the use of botulinum toxin A.

Drake, Marcus J.

2012-01-01

421

Depression and burnout symptoms among Air Force family medicine providers.  

PubMed

This study investigated the prevalence of depression and burnout symptoms among family medicine providers on active duty in the US Air Force. Results demonstrated that 84% of those surveyed scored positive for degrees of depression symptoms; only sex differences were significant. PMID:24758978

Varner, Derrick F; Foutch, Brian K

2014-05-01

422

Obsessive-Compulsive Spectrum Disorder Symptoms in College Students  

ERIC Educational Resources Information Center

Objective: This study investigated the occurrence of obsessive-compulsive spectrum disorders (OCSDs) and associated symptomology in college students. Participants: Participants included 358 undergraduate students. Results: Results suggest that clinically significant levels of OCSD symptoms are relatively common. Additionally, OCSD symptoms

Sulkowski, Michael L.; Mariaskin, Amy; Storch, Eric A.

2011-01-01

423

Perceived attachment: relations to anxiety sensitivity, worry, and GAD symptoms.  

PubMed

This investigation examined the relation between perceived alienation from parents and peers, anxiety sensitivity (AS), and current worry and generalized anxiety disorder (GAD) symptoms with the goal of expanding the knowledge base on factors that may contribute to the development of AS and its role in worry. The mediating role of AS between perceptions of alienation and current worry and GAD symptoms was also examined. Ninety-four non-clinical worriers completed self-report questionnaires assessing their perceptions of attachment, AS levels, and worry and GAD symptoms. Even after controlling for worry and GAD symptoms, greater perceptions of alienation from mothers and peers were significantly associated with higher AS symptoms. AS as a unitary construct mediated the relation between perceptions of alienation from mothers and peers and worry and GAD symptoms. The facets fear of publicly observable symptoms and fear of cognitive dyscontrol also mediated this relation. The role of alienation in relation to AS, worry, and GAD symptoms is discussed along with directions for future research. PMID:18471800

Viana, Andres G; Rabian, Brian

2008-06-01

424

Development and Pilot Investigation of Behavioral Activation for Negative Symptoms  

ERIC Educational Resources Information Center

Negative symptoms cause functional impairment and impede recovery from psychosis, not least, because of limited developments in empirically validated treatments. This article details a pilot evaluation of a behavioral activation (BA) treatment with eight people presenting with psychosis and marked negative symptoms. The rationale for this…

Mairs, Hilary; Lovell, Karina; Campbell, Malcolm; Keeley, Philip

2011-01-01

425

Neuropsychological frontal impairments and negative symptoms in schizophrenia  

Microsoft Academic Search

Negative symptoms have been associated with frontal lobe dysfunction in schizophrenia. However, neuropsychological studies that evaluated the correlation between performance in tests sensitive to the dorsolateral prefrontal cortex (DLPFC) and negative symptoms have shown inconsistent results. Growing evidence has appeared that not only the DLPFC but other prefrontal regions could be involved in schizophrenia. We evaluated schizophrenic patients and healthy

Diego J. Martino; Demián Bucay; Judith T. Butman; Ricardo F. Allegri

2007-01-01

426

Symptoms and signs in patients with suspected neuropathic pain  

Microsoft Academic Search

The study sought to determine if symptoms and signs cluster differentially in groups of patients with increasing evidence of neuropathic pain (NP). We prospectively looked at symptoms and signs in 214 patients with suspected chronic NP of moderate to severe intensity. According to a set of clinical criteria the patients were a priori classified as having the so-called ‘Definite NP’

Peter Vestergaard Rasmussen; Søren Hein Sindrup; Troels Staehelin Jensen; Flemming Winther Bach

2004-01-01

427

Internalizing Symptoms in Latinos: The Role of Anxiety Sensitivity  

ERIC Educational Resources Information Center

Latin American youth in the United States tend to report more internalizing symptoms than white non-Latino youth, yet little is known about the factors that may contribute to such differences. The present study examined the role that anxiety sensitivity, gender, and ethnic minority status may play in the expression of internalizing symptoms across…

Varela, R. Enrique; Weems, Carl F.; Berman, Steven L.; Hensley, Lauren; de Bernal, Maria Clara Rodriguez

2007-01-01

428

Gender Differences in Symptoms of Autism Spectrum Disorders in Toddlers  

ERIC Educational Resources Information Center

Gender differences in symptoms representing the triad of impairments of Autism Spectrum Disorders remain unclear. To date, the majority of research conducted on this topic has utilized samples of older children. Thus, the purpose of the current study was to utilize a sample of toddlers to investigate gender differences in symptom endorsements of…

Sipes, Megan; Matson, Johnny L.; Worley, Julie A.; Kozlowski, Alison M.

2011-01-01

429

Ethnic Differences in Symptoms Experienced During the Menopausal Transition  

Microsoft Academic Search

My purpose in this study was to explore ethnic differences in symptoms experienced during the menopausal transition among four major ethnic groups in the United States using a feminist perspective. This was a cross-sectional correlational study among 158 midlife women. The instruments included are questions on sociodemographic characteristics, health, and menopausal status, and the Midlife Women's Symptom Index (MSI). The

Eun-Ok Im

2009-01-01

430

Predictors of Trauma-Related Symptoms among Runaway Adolescents  

ERIC Educational Resources Information Center

Little is known about trauma-related symptoms among runaway adolescents. Precocious departure from familial homes often exposes youth to traumatic victimization. This study examined the extent to which runaway adolescents present trauma symptomotology and assessed factors that predict trauma symptoms. Participants (N = 350) were 12-18 years of age…

McCarthy, Michael D.; Thompson, Sanna J.

2010-01-01

431

Recent Advances in the Understanding of Negative Symptoms in Schizophrenia  

Microsoft Academic Search

The aim of this article is to provide a comprehensive and concise review of existing literature and findings about negative symptoms associated with the diagnosis of schizophrenia. Significant progress has been made regarding the awareness of negative symptoms associated with schizophrenia. Given this progress, psychiatric nurses shouldfind it useful to have information about how to provide state-of-the-art care and clinical

Steven H. Littrell; Kimberly H. Littrell

1997-01-01

432

Recent advances in the understanding of negative symptoms in schizophrenia  

Microsoft Academic Search

The aim of this article is to provide a comprehensive and concise review of existing literature and findings about negative symptoms associated with the diagnosis of schizophrenia. Significant progress has been made regarding the awareness of negative symptoms associated with schizophrenia. Given this progress, psychiatric nurses should find it useful to have information about how to provide state-of-the-art care and

Steven H Littrell; Kimberly H Littrell

1997-01-01

433

Adolescent Sexual Activity: Links between Relational Context and Depressive Symptoms  

ERIC Educational Resources Information Center

Little is known about the impact of the relational context of adolescent sexual activity on depressive symptoms. The present study examined trajectories of depressive symptoms among 6,602 adolescents (44% male, 60% White) taken from a nationally representative study (Add Health). Sexually active youth in romantic and casual relationships were…

Monahan, Kathryn C.; Lee, Joanna M.

2008-01-01

434

Frequency of Persistent Anal Symptoms After First Instrumental Delivery  

Microsoft Academic Search

PURPOSE: This study was designed to evaluate persistent anal symptoms after first instrumental delivery beyond the postpartum period. METHODS: This prospective study was performed in a cohort of primiparas who underwent instrumental delivery from January 1, 2001 to September 30, 2002. Questionnaires for anal symptoms were completed in the maternity ward on the day after delivery and by mail or

Chafika Mazouni; Florence Bretelle; Samy Battar; Pascal Bonnier; Marc Gamerre

2005-01-01

435

Soyfem® - valuable compound in therapy of menopausal symptoms  

Microsoft Academic Search

Recently much attention has been paid for isoflavones and their proprieties to al- leviate the climacteric symptoms. The goal of this study was to evaluate the efficacy of standardized isoflavones extract (Soyfem) in moderate and medium-severe cli- macteric syndrome. Evaluation of phytoestrogens reach diet in alleviation of climac- teric symptoms were performed in many randomized studies. Most of them showed

436

Coping in Marital Dyads: Patterns and Associations with Psychological Symptoms.  

ERIC Educational Resources Information Center

Examined data from 153 married couples to determine their patterns of coping with stress and association between couples' coping and psychological symptoms in each spouse. Found pattern of dyadic coping marked by strong reliance on escape-avoidance coping by both husband and wife was associated with high levels of symptoms in both spouses.…

Giunta, Carole T.; Compas, Bruce E.

1993-01-01

437

Assessing Secondary Control and Its Association with Youth Depression Symptoms  

ERIC Educational Resources Information Center

Extensive research has linked youth depression symptoms to low levels of perceived control, using measures that reflect "primary control" (i.e., influencing objective conditions to make them fit one's wishes). We hypothesized that depressive symptoms are also linked to low levels of "secondary control" (i.e., influencing the psychological impact…

Weisz, John R.; Francis, Sarah E.; Bearman, Sarah Kate

2010-01-01

438

Premenstrual Symptoms in Mexican Women With Different Educational Levels  

Microsoft Academic Search

Most women present some premenstrual symptoms, which may be influenced by diverse sociocultural factors. The authors studied the premenstrual symptoms of 89 healthy Mexican women living in rural areas and whose education ranged from no schooling to middle school attendance, and 182 women living in urban areas whose education ranged from elementary school to professional studies. The Menstrual Distress Questionnaire

María Luisa Marván; Maricarmen Díaz-Erosa; Aline Montesinos

1998-01-01

439

Marriage, Work, and Depressive Symptoms among Mexican Americans  

Microsoft Academic Search

Sex differences in depressive symptomatology among Mexican Americans are examined using data from two sample surveys conducted in Alameda County, California, in 1975 and 1978. In both studies, women reported more depressive symptoms than men, even after controlling for the effects of age, education, and income. Among the married, the employed reported fewer depressive symptoms than the nonemployed, and controlling

Robert E. Roberts; Catherine Ramsay Roberts

1982-01-01

440

Mood and behavioral symptoms in individuals with chronic solvent exposure  

Microsoft Academic Search

Psychiatric symptoms have been reported for individuals who experience chronic exposure to low levels of organic solvents. However, it is not known what proportion of such individuals experience psychiatric disorder; which specific disorders may be characteristic of this population; or whether bioaccumulation of lead contributes to the relationship between solvent exposure and psychiatric symptoms. Twenty-nine male journeymen painters and 32

Ruth Condray; Lisa A. Morrow; Stuart R. Steinhauer; Michael Hodgsonc; Mary Kelley

2000-01-01

441

Prevalence of work-aggravated symptoms in clinically established asthma.  

PubMed

This population-based cross-sectional survey assessed the prevalence of work-aggravated asthma symptoms and the effect of the work environment on the aggravation of symptoms of established asthma. A questionnaire was sent to 2,613 persons (aged 20-65 yrs) with asthma. The analyses were restricted to the 969 respondents who were currently employed. The effect of occupational exposure on the aggravation of asthma symptoms at work was assessed according to both self-reported and expert-evaluated exposure. Approximately 21% of the respondents reported work-aggravated asthma symptoms at least weekly during the past month. The prevalence of those with work-aggravated symptoms increased by age, self-reported occupational exposure to dusts, abnormal temperatures or poor indoor air quality, physically strenuous work, and chemicals, and expert-evaluated probability of daily occupational exposure to airborne dusts, gases or fumes. Aggravation of asthma symptoms at work is common among employed adults with asthma. Both self-reported and expert-evaluated exposure to dusts, abnormal temperatures or poor indoor air quality, physically strenuous work, and chemicals explained the significant worsening of symptoms. The findings suggest a marked role of the work environment in the aggravation of symptoms of established asthma. PMID:12952265

Saarinen, K; Karjalainen, A; Martikainen, R; Uitti, J; Tammilehto, L; Klaukka, T; Kurppa, K

2003-08-01

442

Smoking and Depressive Symptoms in a College Population  

ERIC Educational Resources Information Center

A number of studies have documented the relationship between smoking and depression in adolescent and adult populations. The purpose of this study was to examine the level of depressive symptoms among college-age smokers and to determine whether or not increases in cigarette use were associated with increases in the number of depressive symptoms.…

Ridner, S. Lee; Staten, Ruth R.; Danner, Fred W.

2005-01-01

443

Etiological and Clinical Features of Childhood Psychotic Symptoms  

PubMed Central

Context It has been reported that childhood psychotic symptoms are common in the general population and may signal neurodevelopmental processes that lead to schizophrenia. However, it is not clear whether these symptoms are associated with the same extensive risk factors established for adult schizophrenia. Objective To examine the construct validity of children’s self-reported psychotic symptoms by testing whether these symptoms share the risk factors and clinical features of adult schizophrenia. Design Prospective, longitudinal cohort study of a nationally representative birth cohort in Great Britain. Participants A total of 2232 twelve-year-old children followed up since age 5 years (retention, 96%). Main Outcome Measure Children’s self-reported hallucinations and delusions. Results Children’s psychotic symptoms are familial and heritable and are associated with social risk factors (eg, urbanicity); cognitive impairments at age 5; home-rearing risk factors (eg, maternal expressed emotion); behavioral, emotional, and educational problems at age 5; and comorbid conditions, including self-harm. Conclusions The results provide a comprehensive picture of the construct validity of children’s self-reported psychotic symptoms. For researchers, the findings indicate that children who have psychotic symptoms can be recruited for neuroscience research to determine the pathogenesis of schizophrenia. For clinicians, the findings indicate that psychotic symptoms in childhood are often a marker of an impaired developmental process and should be actively assessed.

Polanczyk, Guilherme; Moffitt, Terrie E.; Arseneault, Louise; Cannon, Mary; Ambler, Antony; Keefe, Richard S. E.; Houts, Renate; Odgers, Candice L.; Caspi, Avshalom

2013-01-01

444

Cannabis dependence and psychotic symptoms in young people  

Microsoft Academic Search

Background. The aims of this research were to use data gathered over the course of a 21 year longitudinal study to examine the linkages between cannabis dependence at ages 18 and 21 and rates of psychotic symptoms taking into account previous symptom levels and other confounding factors. Method. Data were gathered during the course of the Christchurch Health and Development

2003-01-01

445

Structure of Obsessive-Compulsive Symptoms in Pediatric OCD  

ERIC Educational Resources Information Center

The investigation of the structure of obsessive-compulsive disorder (OCD) symptoms observed in adults is similar to those observed in children is presented. This investigation indicates the structure of OCD symptoms is the same across the entire lifespan as compared to pediatric OCD and adulthood OCD.

Mataix-Cols, David; Nakatani, Eriko; Micali, Nadia; Heyman, Isobel

2008-01-01

446

Pubertal Maturation and African American Children's Internalizing and Externalizing Symptoms  

ERIC Educational Resources Information Center

The association of pubertal maturation with internalizing and externalizing symptoms was examined with a sample of 867 African-American 10-12-year-old children. Children reported their pubertal development status and timing using a self-report questionnaire, and symptoms were assessed through diagnostic interviews with the children and their…

Ge, Xiaojia; Brody, Gene H.; Conger, Rand D.; Simons, Ronald L.

2006-01-01

447

Physical Symptoms and Psychological Distress among Inhalant Users.  

ERIC Educational Resources Information Center

Among 110 Mexican-American adolescents with varying drug use histories, self-reported physical health problems were not related to inhalant use history, but blood analyses indicated a relationship between extensive inhalant use and liver problems. Psychological distress symptoms were related to inhalant use and physical symptoms. Contains 23…

Joe, George W.; And Others

1991-01-01

448

De-constructing depersonalization: further evidence for symptom clusters.  

PubMed

Depersonalization disorder is defined in the DSM-IV-TR using a single symptom criterion, which does not do justice to the phenomenological complexity of the disorder. In 394 affected adults, the Cambridge Depersonalization Scale yielded five factors (numbing, unreality of self, perceptual alterations, unreality of surroundings, and temporal disintegration), put forth as symptom criteria for a better diagnosis of depersonalization disorder. PMID:17959254

Simeon, Daphne; Kozin, David Stephen; Segal, Karina; Lerch, Brenna; Dujour, Roxanne; Giesbrecht, Timo

2008-01-15

449

Motor conversion symptoms and pseudoseizures: a comparison of clinical characteristics  

Microsoft Academic Search

The authors prospectively studied consecutive neurological inpatients with either motor conversion symptoms or pseudoseizures of recent onset. Patients were administered a structured psychiatric diagnostic interview, a measure of perceived parental care, and a life events inventory. They found that patients with pseudoseizures (N=20, mean age=27 years): 1) were younger than patients with motor conversion symptoms (N=30, mean age=39 years), 2)

Jon Stone; Michael Sharpe; Michael Binzer

2004-01-01

450

Age Differences and Similarities in the Correlates of Depressive Symptoms  

Microsoft Academic Search

The authors investigated whether several life events or concerns were differentially related to depressive symptoms across 3 adult age groups (young adults, middle-aged adults, and older adults). They examined the relationships of 2 measures of depressive symptoms to work status and satisfaction, relationship status and satisfaction, loneliness, recent losses, parenting strain, and caregiving. Some differences between age groups in these

Susan Nolen-Hoeksema; Cheryl Ahrens

2002-01-01

451

Age differences and similarities in the correlates of depressive symptoms  

Microsoft Academic Search

The authors investigated whether several life events or concerns were differentially related to depressive symptoms across 3 adult age groups (young adults, middle-aged adults, and older adults). They examined the relationships of 2 measures of depressive symptoms to work status and satisfaction, relationship status and satisfaction, loneliness, recent losses, parenting strain, and caregiving. Some differences between age groups in these

Susan Nolen-Hoeksema; Cheryl Ahrens

2002-01-01

452

SYMPTOMS IN CHILDREN WITH ADVANCED CANCER: CHILD AND NURSE REPORTS  

PubMed Central

Background Systematic studies on the specific symptom experience in children with advanced cancer are limited. Objective To examine common symptoms and to explore commonly occurring symptoms over time. Methods A prospective and longitudinal study design was used. Data were collected at 10 data points from 60 children over a 5-month period. Children ranged from 6 to 17 years old, spoke English or Spanish, were diagnosed with advanced cancer, and were receiving health care in one of four Southern California hospitals. Nurses documentation of symptoms were examined. Results Sample: Children 52% 6–12 years and 48% 13–17 years; 42% female, 58% male; 55% Latino and 30% Caucasian. Pain, nausea, drowsiness and energy loss were reported by children in over 50% of the interviews. Children’s and nurses’ reports of symptoms were similar except children reported significantly more frequency and intensity of pain. Conclusions Children with advanced cancer were able to report and describe their symptoms. There were few differences by gender, age, and ethnicity. Implications for Practice It is important that children’s symptoms are clearly communicated to nurses and these study findings may be used to anticipate and manage the symptoms experienced by children with advanced cancer.

Van Cleve, Lois; Munoz, Cynthia E.; Savedra, Marilyn; Riggs, Matt; Bossert, Elizabeth; Grant, Marcia; Adlard, Kathleen

2011-01-01

453

Relationship between Patient Symptoms and Endosonographic Findings in Chronic Pancreatitis  

Microsoft Academic Search

Background\\/Aims: The endoscopic ultrasound (EUS) diagnosis of chronic pancreatitis (CP) relies on the presence of up to nine distinct pancreatic parenchymal and ductal abnormalities, without considering other factors such as age, duration of disease or clinical symptoms. Our goal was to examine the impact of patient symptoms on EUS findings in patients with CP. Methods: All patients with previously suspected

Timothy B. Gardner; Eileen M. Janec; Stuart R. Gordon

2009-01-01

454

Depressive symptoms and neurocognitive performance among HIV-infected women.  

PubMed

The aims of this article were to explore the relationship between depressive symptoms and neuropsychological performance in a sample of HIV-infected women, and to examine the contribution of demographic, HIV-related variables, and depressive symptoms to neurocognitive performance. In this cross-sectional study, a sample of 103 HIV-infected women, recruited from February to December 2010, were assessed for depressive symptoms (with the Beck Depression Inventory) and neurocognitive performance (with the HIV Dementia Scale). Severe depressive symptoms were reported by 31.1% of the women. Findings indicated that severe levels of depressive symptoms were significantly associated with reduced cognitive functioning in HIV-infected women, particularly in domains of attention, psychomotor speed, and construction. Older age and low education level were significantly associated with neurocognitive impairment in univariate analyses. In the multivariate model, only depressive symptoms were significantly related to neurocognitive impairment. Compared to participants with none/minimal depressive symptoms, those with moderate and severe depressive symptoms had odds ratios for neurocognitive impairment of 5.03 (95% CI, 1.33-18.99) and 3.22 (95% CI, 1.15-9.06), respectively. These findings support continued investigation of the presence of neurocognitive impairment, particularly among women, and may help mental health providers with early detection, planning, and implementation of more effective interventions. The current study was supported by Abbott Laboratories, Portugal. PMID:23517511

Fialho, Renata Margalho; Pereira, Marco; Mendonça, Nuno; Ouakinin, Sílvia

2013-01-01

455

Trauma and PTSD Symptoms: Does Spiritual Struggle Mediate the Link?  

PubMed

Because exposure to potentially traumatic events is common (Kessler, Sonnega, Bromet, & Hughes, 1995), the mechanisms through which post-traumatic stress disorder (PTSD) symptoms develop is a critical area of investigation (Ozer, Best, Lipsey, & Weiss, 2003). Among the mechanisms that may predict PTSD symptoms is spiritual struggle, a set of negative religious cognitions related to understanding or responding to stressful events. Although prominent theories emphasize cognitive factors in the development and maintenance of PTSD symptoms, they have not explicitly addressed spiritual struggle. The present prospective study tested the role of spiritual struggle in the development and maintenance of PTSD symptoms following trauma. We assessed exposure to trauma and non-trauma events during the first year of college, spiritual struggle due to the most stressful event, and PTSD symptoms resulting from the index event. Spiritual struggle partially mediated the relationship between trauma and PTSD symptoms. Interestingly, some individual subscales of spiritual struggle (specifically, Punishing God Reappraisal, Reappraisal of God's Powers, and Spiritual Discontent) partially mediated the relationship between trauma and PTSD symptoms; however, reappraisal of the event to evil forces did not relate to PTSD symptoms. These results suggest that spiritual struggle is an important cognitive mechanism for many trauma victims and may have relevance for cognitive therapy for PTSD. PMID:22308201

Wortmann, Jennifer H; Park, Crystal L; Edmondson, Donald

2011-01-01

456

Effects of Retirement and Grandchild Care on Depressive Symptoms  

ERIC Educational Resources Information Center

This study explores how grandchild care in conjunction with grandparents' retirement affects depressive symptoms, using data from the Health and Retirement Survey. The findings demonstrate that retirement moderates the influence of grandchild care obligations on well-being, measured by depressive symptoms. For retired men, freedom from grandchild…

Szinovacz, Maximiliane E.; Davey, Adam

2006-01-01

457

Stress, Symptom Proneness, and General Adaptational Distress During Pregnancy  

Microsoft Academic Search

Symptom proneness (SP), the 20 psychiatric items of the Cornell Medical Index, here called the Cornell Psychiatric Items (CPI), and a test developed partially from the Schedule of Recent Experiences called the Utah Stress Scales (STRESS) were used to predict general adaptational distress (GAD) symptoms during pregnancy on a sample of 1306 primigravidas. The causal model explored in seven path

Nancy Fagley; Paul Miller; John Sullivan

1982-01-01

458

What Are the Signs and Symptoms of Aplastic Anemia?  

MedlinePLUS

... Signs and Symptoms of Low Blood Cell Counts Red Blood Cells The most common symptom of a low red blood cell count is fatigue (tiredness). A lack ... fatigue. Hemoglobin is an iron-rich protein in red blood cells. It helps carry oxygen to the ...

459

Association of chronic urinary symptoms in women and Ureaplasma urealyticum  

Microsoft Academic Search

Objectives. To determine the incidence of Ureaplasma urealyticum in women experiencing chronic urinary symptoms and to determine whether antibiotic therapy targeting these organisms is effective.Methods. Forty-eight consecutive women referred to our academic medical center for chronic voiding symptoms and possible interstitial cystitis underwent urologic evaluation, including culture screening for U. urealyticum and Mycoplasma hominis. Patients with positive cultures were treated

Jeannette M Potts; A. Michele Ward; Raymond R Rackley

2000-01-01

460

Gender Role Orientation and Anxiety Symptoms among African American Adolescents  

ERIC Educational Resources Information Center

The present study evaluated gender role theory as an explanation for the observed gender differences in anxiety symptoms among adolescents. Specifically, the relation between gender, gender role orientation (i.e., masculinity and femininity), self-esteem, and anxiety symptoms was examined in a community sample of 114 African Americans aged 14 to…

Palapattu, Anuradha G.; Kingery, Julie Newman; Ginsburg, Golda S.

2006-01-01

461

[Symptoms of ovarian failure after hysterectomy in premenopausal women. A retrospective study based on postoperative perception of 245 women].  

PubMed

A total of 437 patients who had undergone hysterectomy in the department of Obstetrics and Gynaecology, Heinrich Braun Clinic, Zwickau, between 1982 and 1992 were asked about vegetative and psychological problems after the operation. All were under 42 years old and had at least one ovary left intact. In all, 245 women returned the questionnaires. After hysterectomy 26.1% reported ovarian failure and 36.7% did not observe typical menopausal symptoms. Symptoms were significantly more frequent in patients where ovary had been removed. It made no difference whether a vaginal or an abdominal incision had been made. Psychic problems were reported by 17.6% of the patients. Patients with ovarian failure had more negative symptoms. Postoperatively, 34 women received hormonal therapy, and 10 of them finished the therapy successfully. The rate of ovarian failure and psychic symptoms can be reduced by adequate information before and after hysterectomy. A decision to perform a hysterectomy should be made only if the operations is strictly indicated. Prophylactic oophorectomy should not be performed in patients under 50 years. Effective hormonal substitution is recommended for patients with menopausal symptoms. PMID:8651007

Habelt, K; Brosche, T; Riedel, H H

1996-01-01

462

Operation of Wastewater Treatment Plants, Manual of Practice No. 11.  

ERIC Educational Resources Information Center

This book is intended to be a reference or textbook on the operation of wastewater treatment plants. The book contains thirty-one chapters and three appendices and includes the description, requirements, and latest techniques of conventional unit process operation, as well as the symptoms and corrective measures regarding process problems. Process…

Albertson, Orrie E.; And Others

463

Restricting Symptoms in the Last Year of Life  

PubMed Central

IMPORTANCE Freedom from symptoms is an important determinant of a good death, but little is known about symptom occurrence during the last year of life. OBJECTIVE To evaluate the monthly occurrence of physical and psychological symptoms leading to restrictions in daily activities (ie, restricting symptoms) among older persons during the last year of life and to determine the associations of demographic and clinical factors with symptom occurrence. DESIGN, SETTING, AND PARTICIPANTS Prospective cohort study. Comprehensive assessments were completed every 18 months, and monthly interviews were conducted to assess the presence of restricting symptoms. Of 1002 nondisabled community-dwelling individuals 70 years or older in greater New Haven, Connecticut, eligible to participate, 754 agreed and were enrolled between 1998 and 1999. MAIN OUTCOMES AND MEASURES The primary outcome was the monthly occurrence of restricting symptoms as a dichotomous outcome. The monthly mean count of restricting symptoms was a secondary outcome. RESULTS Among the 491 participants who died after their first interview and before June 30, 2011, mean age at death was 85.8 years, 61.9% were women, and 9.0% were nonwhite. The mean number of comorbid conditions was 2.4, and 73.1% had multimorbidity. The monthly occurrence of restricting symptoms was fairly constant from 12 months before death (20.4%) until 5 months before death (27.4%), when it began to increase rapidly, reaching 57.2% in the month before death. In multivariable analysis, age younger than 85 years (odds ratio [OR], 1.30 [95% CI, 1.07–1.57]), multimorbidity (OR, 1.38 [95% CI, 1.09–1.75]), and proximity to time of death (OR, 1.14 per month [95% CI, 1.11–1.16]) were significantly associated with the monthly occurrence of restricting symptoms. Participants who died of cancer had higher monthly symptom occurrence (OR, 1.80 [95% CI, 1.03–3.14]) than participants who died of sudden death, although this difference was only marginally significant (P = .04). Symptom burden did not otherwise differ substantially according to condition leading to death. CONCLUSIONS AND RELEVANCE Restricting symptoms are common during the last year of life, increasing substantially approximately 5 months before death. Our results highlight the importance of assessing and managing symptoms in older patients, particularly those with multimorbidity.

Chaudhry, Sarwat I.; Murphy, Terrence E.; Gahbauer, Evelyne; Sussman, L. Scott; Allore, Heather G.; Gill, Thomas M.

2014-01-01

464

Anxiety Changes Depersonalization and Derealization Symptoms in Vestibular Patients  

PubMed Central

Background. Depersonalization and derealization are common symptoms reported in the general population. Objective. The aim of the present study was to establish the relationship between anxiety and depersonalization and derealization symptoms in patients with peripheral vestibular disorders. Methods. Twenty-four vestibular patients with anxiety and 18 vestibular patients without anxiety were examined for depersonalization and derealization symptoms. They were also compared to healthy controls. Results. The results revealed that anxiety consistently changes depersonalization and derealization symptoms in vestibular patients. They are more frequent, more severe, and qualitatively different in vestibular patients with anxiety than in those without anxiety. Conclusion. Anxiety has an effect on depersonalization and derealization symptoms in vestibular patients. The various hypotheses about the underlying mechanism of this effect were discussed.

Kolev, Ognyan I.; Georgieva-Zhostova, Spaska O.; Berthoz, Alain

2014-01-01