These are representative sample records from Science.gov related to your search topic.
For comprehensive and current results, perform a real-time search at Science.gov.
1

Symptom Resolution After Operative Management of Complications From Transvaginal Mesh  

PubMed Central

OBJECTIVE Complications from transvaginal mesh placed for prolapse often require operative management. The aim of this study is to describe the outcomes of vaginal mesh removal. METHODS A retrospective review of all patients having surgery by the Urogynecology group in the Department of Obstetrics & Gynecology at our institution for a complication of transvaginal mesh placed for prolapse was performed. Demographics, presenting symptoms, surgical procedures, and postoperative symptoms were abstracted. Comparative statistics were performed using the chi-squared or Fisher’s exact test with significance at p<0.05. RESULTS Between January 2008 and April 2012, 90 patients had surgery for complications related to vaginal mesh and 84 had follow-up data. The most common presenting signs and symptoms were: mesh exposure 62% (n=56), pain 64% (n=58), and dyspareunia 48% (n=43). During operative management, mesh erosion was encountered unexpectedly in a second area of the vagina in 5% (n=4), in the bladder in 1% (n=1), and in the bowel in 2% (n=2). After vaginal mesh removal, 51% (n=43) had resolution of all presenting symptoms. Mesh exposure was treated successfully in 95% of cases, while pain was only successfully treated in 51% of women. CONCLUSION Removal of vaginal mesh is helpful in relieving symptoms of presentation. Patients can be reassured that exposed mesh can almost always be successfully managed surgically, but pain and dyspareunia are only resolved completely in half of cases. PMID:24463673

Crosby, Erin C.; Abernethy, Melinda; Berger, Mitchell B.; DeLancey, John O.; Fenner, Dee E.; Morgan, Daniel M.

2014-01-01

2

Symptoms  

MedlinePLUS

... swallowing Shortness of breath or wheezing Turning blue Drop in blood pressure (feeling faint, confused, weak, passing ... Resources About Anaphylaxis Allergens Peanut Tree Nuts Milk Egg Wheat Soy Fish Shellfish Other Symptoms Diagnosis & Testing ...

3

Spesialiserte metoder for avdekking av malingering i nevropsykologiske undersøkelser : en vurdering og sammenligning av symptomvaliditetstester og spørreskjema .  

E-print Network

??"Malingering" refererer til et klinisk fenomen hvor en person, motivert av ytre insentiver, bevisst og intensjonelt produserer falske eller grovt overdrevne fysiske eller psykiske symptomer.… (more)

Puhr, Anita

2007-01-01

4

Special operations forces and incidence of post-traumatic stress disorder symptoms.  

PubMed

To determine the rates of Post-traumatic Stress Disorder (PTSD) positive symptom scores in Special Operations Forces (SOF) personnel, an anonymous survey of SOF was employed, incorporating the PTSD Checklist (PCL-M) with both demographic and deployment data. Results indicate that all SOF units studied scored above the accepted cut-offs for PTSD positive screening.1 When total symptom severity score exceeded established cutoff points and were combined with criteria for Diagnostic and Statistical Manual of Mental Disorders, Edition 4 (DSM-IV) diagnosis of PTSD,2 approximately 16?20% of respondents met scoring threshold for positive screening, almost double those of conventional Army units. Collectively, Special Forces (SF) Soldiers and SOF combat-arms Soldiers had significantly higher PLC-M scores than their non-combat-arms SOF counterparts. SOF Soldiers with three or more deployments to Afghanistan had significantly higher PCL-M scores. Considering the evidence suggesting that SOF Soldiers are hyper-resilient to stress, these results should drive further research schemata and challenge clinical assumptions of PTSD within Special Operations. PMID:23032317

Hing, Matthew; Cabrera, Jorge; Barstow, Craig; Forsten, Robert

2012-01-01

5

Inklusion og eksklusion  

Microsoft Academic Search

Begreberne differentiering og integration har en lang tradition i sociologisk teori. Spørgsmålet er imidlertid, om man ikke overbelaster dette begrebspars forklaringsevne, især når man står over for særlige problemer i udviklingslande og bestemte problemer, der er fælles for ulande og ilande. Artiklen foreslår, at sociologien suppleres med begrebsparret inklusion\\/eksklusion. Det vises, hvordan inklusions- og eksklusionsforholdene varierer fra segmentært over stratificeret

Niklas Luhmann

2002-01-01

6

Evaluation of respiratory symptoms and respiratory protection behavior among poultry workers in small farming operations.  

PubMed

Agricultural workers who work in enclosed poultry operations are at increased risk of respiratory exposure to atmospheric contaminants, including dusts, endotoxins, particulate from feathers, ammonia, and hydrogen sulfide from animal excrement. Given the relatively large number of small, family-run poultry farms in North Carolina, there has been relatively little research in the area documenting human lung function and perception of using respiratory protection among poultry workers. This study assesses respiratory health, knowledge, and perception of wearing respiratory protection among a sample of poultry workers attending a regional farm show in North Carolina. Lung function (spirometry), airway inflammation (exhaled nitric oxide), self-reported respiratory symptoms, and behavior of wearing respiratory protection were evaluated. Overall, mean lung function values were slightly lower than normal predicted values. The majority of participants ranked using respiratory protection as very important (51.9%); however, actual self-reported behavior was low (16.7%). In bivariate analysis, associations between the importance of wearing respiratory protection and the number of poultry houses (P=.04), as well as using a respirator and the number of poultry houses (P=.01) were statistically significant. Improved educational opportunities, including fit-testing and proper respiratory selection, should be emphasized for workers at small, poultry farm operations. PMID:24911691

Kearney, Gregory D; Shaw, Robert; Prentice, Matthew; Tutor-Marcom, Robin

2014-01-01

7

Individual and work related factors associated with symptoms of musculoskeletal complaints. II. Different risk factors among sewing machine operators.  

PubMed

Individual and work related risk factors in the development of occupational musculoskeletal complaints were studied in a group of 210 female production workers, mainly sewing machine operators. Another group of 35 female employees performing secretarial or laboratory duties were also included. The production workers had significantly higher symptom scores with respect to self reported musculoskeletal complaints than the group with more varied work tasks for the head, neck, shoulders, and arms, but not for the low back, hips, and the lower extremities. No significant differences were found in symptom level between geographically separate groups of production workers with similar work tasks. The main individual risk factor identified in this study was the experience of previous, similar symptoms in the same body region, but this factor only accounted for 2-3% of total variance in symptom score for the neck and shoulders. Other individual factors of importance for symptoms in the neck and shoulders were "signs of psychological problems" and "tendency of muscle tension," but these only account for about 1% of total variance in symptom score. Symptoms in the head and low back showed complex relations with individual parameters. PMID:1554612

Westgaard, R H; Jansen, T

1992-03-01

8

Individual and work related factors associated with symptoms of musculoskeletal complaints. II. Different risk factors among sewing machine operators  

Microsoft Academic Search

Individual and work related risk factors in the development of occupational musculoskeletal complaints were studied in a group of 210 female production workers, mainly sewing machine operators. Another group of 35 female employees performing secretarial or laboratory duties were also included. The production workers had significantly higher symptom scores with respect to self reported musculoskeletal complaints than the group with

R H Westgaard; T Jansen

1992-01-01

9

Screening for Depressive Disorders Using the Mood and Anxiety Symptoms Questionnaire Anhedonic Depression Scale: A Receiver-Operating Characteristic Analysis  

ERIC Educational Resources Information Center

The present study examined the utility of the anhedonic depression scale from the Mood and Anxiety Symptoms Questionnaire (MASQ-AD scale) as a way to screen for depressive disorders. Using receiver-operating characteristic analysis, we examined the sensitivity and specificity of the full 22-item MASQ-AD scale, as well as the 8- and 14-item…

Bredemeier, Keith; Spielberg, Jeffery M.; Silton, Rebecca Levin; Berenbaum, Howard; Heller, Wendy; Miller, Gregory A.

2010-01-01

10

Cloud Computing og availability  

E-print Network

Cloud Computing og availability Projekt i pålidelighed Henrik Lavdal - 20010210 Søren Bardino Kaa - 20011654 Gruppe 8 19-03-2010 #12;Cloud Computing og availability Side 2 af 28 Indholdsfortegnelse ...........................................................................................5 Cloud computing

Christensen, Henrik Bærbak

11

Jarring\\/jolting exposure and musculoskeletal symptoms among farm equipment operators  

Microsoft Academic Search

Vehicle vibration exposure has been linked to chronic back pain and low-back symptoms among agricultural tractor drivers. The objectives of this study by the National Institute for Occupational Safety and Health (NIOSH) were to assess driver whole-body vibration (WBV) exposures and recommend interventions to reduce the risk of back-related injuries, particularly relative to vehicle jarring\\/jolting (the transient mechanical shock components

A. G. Mayton; N. K. Kittusamy; D. H. Ambrose; C. C. Jobes; M. L. Legault

2008-01-01

12

Prevention of upper limb symptoms and signs of nerve afflictions in computer operators: The effect of intervention by stretching  

PubMed Central

Background In a previous study of computer operators we have demonstrated the relation of upper limb pain to individual and patterns of neurological findings (reduced function of muscles, sensory deviations from normal and mechanical allodynia of nerve trunks). The identified patterns were in accordance with neural afflictions at three specific locations (brachial plexus at chord level, posterior interosseous and median nerve on elbow level). We have introduced an intervention program aiming to mobilize nerves at these locations and tested its efficacy. Methods 125 and 59, respectively, computer operators in two divisions of an engineering consultancy company were invited to answer a questionnaire on upper limb symptoms and to undergo a blinded neurological examination. Participants in one division were subsequently instructed to participate in an upper limb stretching course at least three times during workdays in a six month period. Subjects from the other division served as controls. At the end of the intervention both groups were invited to a second identical evaluation by questionnaire and physical examination. Symptoms and findings were studied in the right upper limb. Perceived changes of pain were recorded and individual and patterns of physical findings assessed for both groups at baseline and at follow-up. In subjects with no or minimal preceding pain we additionally studied the relation of incident pain to the summarized findings for parameters contained in the definition of nerve affliction at the three locations. Results Summarized pain was significantly reduced in the intervention group but unchanged in controls. After the intervention, fewer neurological abnormalities in accordance with nerve affliction were recorded for the whole material but no conclusion could be drawn regarding the relation to the intervention of this reduction. Incident pain correlated to findings in accordance with the three locations of nerve affliction. Conclusion A six month course of stretching seems to reduce upper limb symptoms in computer operators but we could not demonstrate an influence on neurological physical findings in this sample. The relation of incident symptoms to identified neurological patterns provides additional support to the construct validity of the employed neurological examination. PMID:18179682

Jepsen, Jorgen R; Thomsen, Gert

2008-01-01

13

DIRECT trial. Diverticulitis recurrences or continuing symptoms: Operative versus conservative Treatment. A MULTICENTER RANDOMISED CLINICAL TRIAL  

Microsoft Academic Search

BACKGROUND: Persisting abdominal complaints are common after an episode of diverticulitis treated conservatively. Furthermore, some patients develop frequent recurrences. These two groups of patients suffer greatly from their disease, as shown by impaired health related quality of life and increased costs due to multiple specialist consultations, pain medication and productivity losses. Both conservative and operative management of patients with persisting

Bryan JM van de Wall; Werner A Draaisma; Esther CJ Consten; Yolanda van der Graaf; Marten H Otten; G de Wit; Henk F van Stel; Michael F Gerhards; Marinus J Wiezer; Huib A Cense; Hein BAC Stockmann; Jeroen WA Leijtens; David DE Zimmerman; Eric Belgers; Bart A van Wagensveld; Eric DJA Sonneveld; Hubert A Prins; Peter PLO Coene; Tom M Karsten; Joost M Klaase; Markwin G Statius Muller; Rogier MPH Crolla; Ivo AMJ Broeders

2010-01-01

14

What Symptom Improvement Can Be Expected After Operation for Primary Hyperparathyroidism?  

Microsoft Academic Search

Background  The only cure for primary hyperparathyroidism (pHPT) is operative resection of the parathyroid gland(s) responsible for the\\u000a disease. The 1990 National Institute of Health’s (NIH) consensus development conference on asymptomatic pHPT and its subsequent\\u000a workshop in 2001 established which clinical criteria warranted parathyroidectomy (PTx) versus observation. While there is\\u000a no debate that these NIH criteria capture a group of patients

Nadine R. Caron; Janice L. Pasieka

2009-01-01

15

Posttraumatic stress symptoms and work-related accomplishment as predictors of general health and medical utilization among Special Operations Forces personnel.  

PubMed

Research has established clear links among posttraumatic stress disorder (PTSD), somatic symptoms, and general health among conventional force military personnel. It is possible that the same relationships exist among Special Operations Force (SOF) personnel, but there are very few, if any, studies that examine these relationships. This study investigated correlates of general health and medical visits among SOF personnel and found that the interaction of somatic and PTSD symptoms was associated with worse health and more frequent medical visits. Follow-up analyses indicated that the interaction of avoidance symptoms with somatic symptoms was significantly associated with worse health, whereas the interaction of emotional numbing with somatic symptoms significantly contributed to increased medical visits. In addition, the results suggest that a sense of accomplishment among SOF personnel may serve as a protective factor against poor health. The results suggest developing interactions among SOF personnel that promote a sense of achievement to ultimately improve the health of the force. PMID:24469521

Bryan, Craig J; Stephenson, James A; Morrow, Chad E; Staal, Mark; Haskell, Jeremy

2014-02-01

16

Automated function generation of symptom parameters and application to fault diagnosis of machinery under variable operating conditions  

Microsoft Academic Search

Dimensional or nondimensional symptom parameters are usually used for condition monitoring of plant machinery. However, it is difficult to extract the most important symptom parameters and the functions of those parameters by which machinery faults can be sensitively detected and the fault types can be precisely distinguished. In order to overcome this difficulty and to ensure highly accurate fault diagnosis,

Peng Chen; Toshio Toyota; Zhengja He

2001-01-01

17

Combat exposure, psychological symptoms, and marital satisfaction in National Guard soldiers who served in Operation Iraqi Freedom from 2005 to 2006  

Microsoft Academic Search

In current military operations in Iraq and Afghanistan, US National Guard (NG) troops are serving longer deployments than ever before. Little is known, however, about how such deployments affect this population of individuals, relative to active component (AC) troops. This study investigated the extent of combat exposure, severity of post-deployment psychological symptoms, and general interpersonal functioning, as well as the

Keith D. Renshaw; Camila S. Rodrigues; David H. Jones

2009-01-01

18

Extraction of feature spectra by instantaneous power spectrum and automatic generation of symptom parameters by GP for diagnosis of machinery in unsteady operating condition  

Microsoft Academic Search

This paper proposes a failure diagnosis method for plant machinery in unsteady operating conditions using the instantaneous power spectrum (IPS) and genetic programming (GP). The IPS is used to extract the feature spectra of each machine state from the measured vibration signal for distinguishing failures by the relative crossing information (RCI). Excellent symptom parameters for detecting failures are automatically generated

M. Taniguchi; Peng Chen; T. Toyota

2000-01-01

19

Symptom Management  

Cancer.gov

Symptom Management & Quality of Life Concept Design This video covers a variety of practical considerations for developing a symptom management concept for clinical research.. Co-sponsored by the National Cancer Institute Symptom Management and Health

20

FREMTID NUTID OG FORTID Besgscenter  

E-print Network

fremtrædende danskere. Læs om Haldor Topsøes betydelige rolle og hans samarbejde med Niels Bohr tilbage i 50'erne. Haldor Topsøe giver også sin mening om fremtidens Risø. Helge Sander: Risø er model for ny fremover: "Jeg har været meget tilfreds med model- len, hvor ministeriet og forskningscenteret indgår en

21

Modellering og regulering af affaldsforbrnding  

E-print Network

found hereby was controled with the following controllers: PID, MV0, PZ and LQG. The controllers were følgende re- gulatorer: PID, MV0, PZ og LQG. Regulatorerne blev undersøgt for deres evne til at f ved- varende ændring i dampproduktionen. Af regulatorerne virkede PID, PZ og LQG. Heraf var de

22

Prevalence of type I allergy to natural rubber latex and type IV allergy to latex and rubber additives in operating room staff with glove-related symptoms.  

PubMed

There is lack of data on the prevalence of latex allergy in the health care setting in Iran. This study was performed to determine the prevalence of type I latex allergy and type IV allergy to latex and rubber additives among the operating room staff with glove-related symptoms in 13 general hospitals in Tehran. Skin-prick tests with commercial latex extract, patch tests with latex and 25 rubber additive series, and total and latex-specific IgE detection were performed on the operating room staff who reported latex glove-related symptoms. Five hundred twelve self-administered questionnaires (100%) were completed by all operating room staff and latex glove-related symptoms were reported by 59 (11.5%) employees. Among all symptomatic operating room staff tested, the prevalence of type I latex allergy was 30.5% and the prevalence rates of type IV allergy to latex and rubber additives were 16.7 and 14.6%, respectively. The most positive patch test result with rubber additives was related to tetramethylthiuram monosulfide (38.5%). The risk factors for type I latex allergy were female sex (p = 0.009) and positive patch test with rubber additives (p = 0.012). Subjects who had positive patch test with latex were significantly more likely to have positive patch test with rubber additives (p < 0.0001). Our results showed a high prevalence of type I latex allergy and type IV allergy to latex and rubber additives. Based on this study, we recommend eliminating powdered latex gloves from the operating rooms of the 13 studied general hospitals and support the substitution of powder-free latex gloves. PMID:18034975

Miri, Sara; Pourpak, Zahra; Zarinara, Alireza; Zarinara, Alam; Heidarzade, Marzieh; Kazemnejad, Anoushirvan; Kardar, Gholamali; Firooz, Alireza; Moin, Athar

2007-01-01

23

Self-report measures to identify post traumatic stress disorder and/or mild traumatic brain injury and associated symptoms in military veterans of Operation Enduring Freedom (OEF)/Operation Iraqi Freedom (OIF).  

PubMed

Individuals serving in Iraq and Afghanistan sustain injuries associated with physical and psychological trauma. Among such injuries, mild traumatic brain injury (mTBI) and post traumatic stress disorder (PTSD) are common. Self-report measures are frequently used to identify mTBI and/or PTSD and symptoms associated with these conditions. In addition to providing information regarding mTBI and PTSD, the goal of this literature review was to identify and present information on the psychometric properties of measures used to obtain information regarding these common conditions among Veterans who have returned from Operation Enduring Freedom (OEF)/Operation Iraqi Freedom (OIF). A comprehensive review of studies in which self-report measures were used to evaluate mTBI, PTSD, and associated symptoms among OEF/OIF Veterans is presented. Findings suggest that additional work is needed to identify psychometrically sound and clinically useful self-report measures that assess mTBI and PTSD and associated symptoms among OEF/OIF Veterans. PMID:22350740

Betthauser, Lisa M; Bahraini, Nazanin; Krengel, Maxine H; Brenner, Lisa A

2012-03-01

24

Rotavirus Symptoms  

MedlinePLUS

... Rotavirus Vaccine Program American Academy of Pediatrics Symptoms Language: English Español (Spanish) Share Compartir Español: SÃntomas Rotavirus ... PATH's Rotavirus Vaccine Program American Academy of Pediatrics Language: English Español (Spanish) File Formats Help: How do I ...

25

Syphilis Symptoms  

MedlinePLUS

... JavaScript on. Read more information on enabling JavaScript. Syphilis Skip Content Marketing Share this: Main Content Area ... occurs in four stages that sometimes overlap. Primary Syphilis The first symptom of primary syphilis is often ...

26

Effects of a standard operating procedure on prehospital emergency care of patients presenting with symptoms of the acute coronary syndrome.  

PubMed

To determine whether a standard operating procedure (SOP) for prehospital management of patients with the acute coronary syndrome (ACS) improves the quality of patient care in terms of adherence to treatment guidelines of the European Society of Cardiology. Among a total of 1025 patient medical records collected from a period before and after the introduction of the SOP, 269 records included the working diagnosis of ACS and were then reviewed for guideline adherence. Most aspects of patient evaluation, monitoring, treatment, and hospital allocation were fairly guideline adherent (>70%) before the SOP was introduced and were not affected by the SOP. The percentage of cases in whom sublingual nitrate (55.2 vs. 66.7%) or intravenous morphine (26.9 vs. 43.0%) was administered without contraindications was higher after the SOP had been introduced. Therefore, the use of an SOP in prehospital emergency medicine can partly improve the adherence to guideline recommendations for the treatment of patients with ACS. PMID:23411814

Francis, Roland C; Bubser, Florian; Schmidbauer, Willi; Spies, Claudia D; Sörensen, Marc; Bosse, Götz; Kerner, Thoralf

2014-06-01

27

Menopausal symptoms  

PubMed Central

Introduction Menopause is a physiological event. In the UK, the median age for onset of menopausal symptoms is 45.5 to 47.5 years. Although endocrine changes are permanent, menopausal symptoms such as hot flushes, which are experienced by about 70% of women, usually resolve with time, although they can persist for decades in some women. Methods and outcomes We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of medical treatments for menopausal symptoms? What are the effects of non-prescribed treatments for menopausal symptoms? We searched: Medline, Embase, The Cochrane Library, and other important databases up to March 2009 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). Results We found 68 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions. Conclusions In this systematic review we present information relating to the effectiveness and safety of the following interventions: agnus castus, antidepressants, black cohosh, clonidine, oestrogens, phyto-oestrogens, progestogens, testosterone, and tibolone. PMID:21718582

2010-01-01

28

Menopausal symptoms  

PubMed Central

Introduction Menopause is a physiological event. In the UK, the median age for onset of menopausal symptoms is 45.5 to 47.5 years. Although endocrine changes are permanent, menopausal symptoms such as hot flushes, which are experienced by about 70% of women, usually resolve with time, although they can persist for decades in some women. Methods and outcomes We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of medical treatments for menopausal symptoms? What are the effects of non-prescribed treatments for menopausal symptoms? We searched: Medline, Embase, The Cochrane Library, and other important databases up to June 2010 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). Results We found 79 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions. Conclusions In this systematic review we present information relating to the effectiveness and safety of the following interventions: agnus castus, antidepressants, black cohosh, clonidine, oestrogens, phyto-oestrogens, progestogens, testosterone, and tibolone. PMID:21696644

2011-01-01

29

Psychosocial buffers of traumatic stress, depressive symptoms, and psychosocial difficulties in veterans of Operations Enduring Freedom and Iraqi Freedom: The role of resilience, unit support, and postdeployment social support  

Microsoft Academic Search

BackgroundLittle research has examined the role of protective factors such as psychological resilience, unit support, and postdeployment social support in buffering against PTSD and depressive symptoms, and psychosocial difficulties in veterans of Operations Enduring Freedom (OEF) and Iraqi Freedom (OIF).

Robert H. Pietrzak; Douglas C. Johnson; Marc B. Goldstein; James C. Malley; Alison J. Rivers; Charles A. Morgan; Steven M. Southwick

2010-01-01

30

Fractured OG tip: a case report.  

PubMed

This case report describes a complication from use of an orogastric tube not previously described in the literature. An OG tube was placed and removed non-traumatically for the anesthetic management for an anterior-posterior cervical spinal fusion. Despite smooth placement and removal, the patient coughed up the tip of the OG tube while in the post anesthesia care unit. Orogastric (OG) and nasogastric (NG) tubes are routinely used in anesthesia as well as many other fields of medicine. OG and NG tubes leading to morbidity are rare; however, this report describes a new potential adverse event that clinicians should be aware of. PMID:24294710

Ranier, George; Costello, Kevin

2013-01-01

31

Karen Blixen: En undersøgelse af identitet og skæbne, etik og moral. - Hvad var det med den der stork?.  

E-print Network

??Projektet indeholder litterære analyser af Karen Blixens kardinalfortællinger. Disse analyseres for at undersøge forståelsen af identitet og skæbne hos Blixen. De to fortællinger sammenholdes, og… (more)

Thiel, Gitte May

2006-01-01

32

Bioteknologien og Frankenstein Dag O. Hessen  

E-print Network

etterkrigstiden; det var Aldous Huxleys Brave New World fra 1932, og George Orwells 1984 fra 1949. Den første var sannhetsrelativisering og en bølge av "new age"-fenomener, som oftest ikledd naturvitenskapens språkdrakt. Barnet ble

Hessen, Dag Olav

33

Symptoms of Pneumocystis pneumonia  

MedlinePLUS

... gov . Fungal Diseases Share Compartir Symptoms of Pneumocystis pneumonia The symptoms of PCP are fever, dry cough, ... Diagnosis & Testing Treatment & Outcomes Statistics Additional Information Pneumocystis pneumonia Definition Symptoms People at Risk & Prevention Sources Diagnosis & ...

34

Symptoms of Parkinson's  

MedlinePLUS

... Secondary Motor Symptoms Nonmotor Symptoms Causes Progression Medications & Treatments Clinical Trials Statistics on Parkinson's Chasing the Cure National HelpLine Educational Publications Online ...

35

“Hvad er tilfældet?” og “Hvad ligger der bag?” De to sociologier og samfundsteorien  

Microsoft Academic Search

Siden begyndelsen af sin akademiske karriere har sociologien nærmet sig sin genstand på to forskellige måder: dels med en positivistisk og dels med en kritisk indstilling. Vigtige teorier—såsom Karl Marx' og Emile Durkheims—har alle foretrukket den ene side af denne forskel, men har ikke derved kunnet ignorere den anden. Som empirisk videnskab har sociologien udviklet en interesse for latente strukturer.

Niklas Luhmann

2000-01-01

36

Elevated PTH After Parathyroidectomy Delays Symptom Improvement  

PubMed Central

Background Curative parathyroidectomy for primary hyperparathyroidism (PHPT) resolves various nonspecific symptoms related to the disease. Between 8 to 40% of patients with normocalcemia after parathyroidectomy have persistently elevated parathyroid hormone levels (ePTH) at follow-up. We investigated whether ePTH in the early post-operative period was associated with the timing of symptom improvement. Materials and Methods This prospective study included adult patients with PHPT who underwent curative parathyroidectomy from November 2011 to September 2012. Biochemical testing 2 weeks post-operatively identified ePTH (defined as PTH > 72 pg/mL) versus normal PTH (nPTH). A questionnaire administered pre- and post-operatively at 6 weeks and 6 months asked patients to rate the frequency of 18 symptoms of PHPT on a 5-point Likert scale. Student’s T-tests were used to compare pre- to post-operative changes in scores for individual symptoms. Results Of 194 patients that underwent parathyroidectomy, 129 (66%) participated in the study. Pre-operatively, all patients were symptomatic, with a mean of 13±4 symptoms. Two weeks post-operatively, 20 patients (16%) had ePTH. The percentage of patients with post-operative improvement for individual symptoms was compared between groups. At the early time point (6 weeks), the ePTH group showed less improvement in 14 of 18 symptoms. This difference reached statistical significance for four symptoms: anxiety, constipation, thirst, and polyuria. By the 6 month time point, these differences had resolved and symptom improvement was similar between groups. Conclusions Elevated PTH after curative parathyroidectomy may result in a delay in symptom improvement 6 weeks post-operatively, however, this difference resolves by 6 months. PMID:24685332

Pathak, Priya R.; Holden, Sara E.; Schaefer, Sarah C.; Leverson, Glen; Chen, Herbert; Sippel, Rebecca S.

2014-01-01

37

Brndselscellers fysik og kemi Anders Smith og Mogens Mogensen, Afdelingen for Materialeforskning, Forskningscenter Ris.  

E-print Network

. For alle typer er bruttoreaktionen den samme: 2H2 + O2 2H2O + elek- tricitet + varme. (eng. "Molten Carbonate Fuel Cell", MCFC) og endelig fastoxidbrændselscellen (eng. "Solid Oxide Fuel Cell", SOFC), som har

38

Vitiligo: Signs and Symptoms  

MedlinePLUS

... Diseases and treatments U - W Vitiligo Signs, symptoms Vitiligo: Signs and symptoms Vitiligo causes loss of color. ... amount of color loss or type of vitiligo. Vitiligo has types and subtypes If you are diagnosed ...

39

Shingles: Signs and Symptoms  

MedlinePLUS

... Diseases and treatments Q - T Shingles Signs, symptoms Shingles: Signs and symptoms Shingles tends to cause more ... painful before the shingles appeared. Learn more about shingles: Shingles Shingles: Who gets, causes Shingles: Diagnosis, treatment, ...

40

E. coli Symptoms  

MedlinePLUS

... JavaScript on. Read more information on enabling JavaScript. E. coli Skip Content Marketing Share this: Main Content Area Symptoms Shiga toxin-producing E. coli (STEC) can cause the following symptoms: Nausea ...

41

Symptoms of Ovarian Cancer  

MedlinePLUS

... Informed Cancer Home What Are the Symptoms of Ovarian Cancer? Language: English Español (Spanish) Share Compartir Gynecologic cancer symptoms diaries Ovarian cancer may cause one or more of these ...

42

Rosacea: Signs and Symptoms  

MedlinePLUS

... Diseases and treatments Q - T Rosacea Signs, symptoms Rosacea: Signs and symptoms Rosacea causes more than a ... ophthalmologist (doctor who specializes in treating eye diseases). Rosacea can affect quality of life Rosacea can affect ...

43

Prostate Cancer Symptoms  

MedlinePLUS

... About the Prostate Risk Factors Prevention Symptoms Early Detection & Screening Living With Prostate Cancer Newly Diagnosed Treatment ... About the Prostate Risk Factors Prevention Symptoms Early Detection & Screening Living With Prostate Cancer Newly Diagnosed Treatment ...

44

EFP-2001 rammeprojekt Elektrisk Design og Styring  

E-print Network

og design af vindmøller (Simulation Platform to Model, Optimize and Design Wind Turbines) Florin Iov and Design Wind Turbines". The motivation for this research project is the ever-increasing wind energy in different simulation tools for a system optimization of the wind turbine systems. Using this model database

45

Impact of symptoms, gender, co-morbidities, and operator volume on outcome of carotid artery stenting (from the Nationwide Inpatient Sample [2006 to 2010]).  

PubMed

The increase in the number of carotid artery stenting (CAS) procedures over the last decade has necessitated critical appraisal of procedural outcomes and patterns of utilization including cost analysis. The main objectives of our study were to evaluate the postprocedural mortality and complications after CAS and the patterns of resource utilization in terms of length of stay (LOS) and cost of hospitalization. We queried the Healthcare Cost and Utilization Project's Nationwide Inpatient Sample from 2006 to 2010 using the International Classification of Diseases, Ninth Revision, procedure code of 00.63 for CAS. Hierarchical mixed-effects models were generated to identify the independent multivariate predictors of in-hospital mortality, procedural complications, LOS, and cost of hospitalization. A total of 13,564 CAS procedures (weighted n = 67,344) were analyzed. The overall postprocedural mortality was low at 0.5%, whereas the complication rate was 8%, both of which remained relatively steady over the time frame of the study. Greater postoperative mortality and complications were noted in symptomatic patients, women, and those with greater burden of baseline co-morbidities. A greater operator volume was associated with a lower rate of postoperative mortality and complications, as well as shorter LOS and lesser hospitalization costs. In conclusion, the postprocedural mortality after CAS has remained low over the recent years. Operator volume is an important predictor of postprocedural outcomes and resource utilization. PMID:25208563

Badheka, Apurva O; Chothani, Ankit; Panaich, Sidakpal S; Mehta, Kathan; Patel, Nileshkumar J; Deshmukh, Abhishek; Singh, Vikas; Arora, Shilpkumar; Patel, Nilay; Grover, Peeyush; Shah, Neeraj; Savani, Chirag N; Patel, Achint; Panchal, Vinaykumar; Brown, Michael; Kaki, Amir; Kondur, Ashok; Mohamad, Tamam; Elder, Mahir; Grines, Cindy; Schreiber, Theodore

2014-09-15

46

Studieordning for Bacheloruddannelse i arabisk-og islamstudier  

E-print Network

kvalifikationer §. 3. En bacheloruddannelse med Arabisk- og islamstudier som centralt fag består af 2¼ års studier i Arabisk- og islamstudier kombineret med ¾ års studier inden for et andet fagligt område eller 2 års studier i Arabisk- og islamstudier kombineret med 1 års studier inden for et andet fagligt område

47

What is called symptom?  

PubMed

There is one concept in medicine which is prominent, the symptom. The omnipresence of the symptom seems, however, not to be reflected by an equally prominent curiosity aimed at investigating this concept as a phenomenon. In classic, traditional or conventional medical diagnostics and treatment, the lack of distinction with respect to the symptom represents a minor problem. Faced with enigmatic conditions and their accompanying labels such as chronic fatigue syndrome, fibromyalgia, medically unexplained symptoms, and functional somatic syndromes, the contestation of the symptom and its origin is immediate and obvious and calls for further exploration. Based on a description of the diagnostic framework encompassing medically unexplained conditions and a brief introduction to how such symptoms are managed both within and outside of the medical clinic, we argue on one hand how unexplained conditions invite us to reconsider and re-think the concept we call a "symptom" and on the other hand how the concept "symptom" is no longer an adequate and necessary fulcrum and must be enriched by socio-cultural, phenomenological and existential dimensions. Consequently, our main aim is to expand both our interpretative horizon and the linguistic repertoire in the face of those appearances we label medically unexplained symptoms. PMID:23877313

Eriksen, Thor Eirik; Risør, Mette Bech

2014-02-01

48

Frontotemporal Disorders: Common Symptoms  

MedlinePLUS

... Information for Patients, Families, and Professionals Understanding Alzheimer's Disease: What You Need to ... Symptoms Treatment and Management Caring for a Person with a Frontotemporal Disorder Conclusion ...

49

Physical symptoms of depression.  

PubMed

The incidence of physical symptoms in depression was studied in 51 drug-free patients and in an age and sex-matched control group. Mean symptom intensity and number of symptoms were significantly higher in the patient than in the control group. The subjects' personality structure and relationships between their symptoms and degrees of depression and anxiety were examined using the Eysenck Personality Inventory (EPI), the Beck Depression Inventory, and the Spielberger State-Trait Anxiety Inventory, respectively. Of the variables studied, only the N score of the EPI was shown to influence the symptoms significantly. The effect of such non-specific factors as age, gender, use of alcohol, coffee, tea, and cigarettes was also evaluated and found to be minimal. PMID:7326538

Mathew, R J; Weinman, M L; Mirabi, M

1981-10-01

50

2D og 3D invers Radon transformation til PET Jesper James Jensen  

E-print Network

2D og 3D invers Radon transformation til PET Jesper James Jensen Frembringelse og tolkning af PET optaget med PET skannere ved hjaelp af den inverse Radon transformation. Der eksisterer forskellige Radon transformation til PET og Frembringelse og tolkning af PET billeder. Disse projekter er udført i

Mosegaard, Klaus

51

Module 3 – Symptoms  

Cancer.gov

Module three of the EPEC-O (Education in Palliative and End-of-Life Care for Oncology) Self-Study Original Version presents approaches to and management of commonly encountered symptoms and syndromes of cancer patients.

52

Chiari Malformation: Symptoms  

MedlinePLUS

... the back of the head, is the defining Chiari symptom Chiari headaches are usually described as starting ... and upper back is another common problem with Chiari due to several causes: nerves are compressed by ...

53

Symptoms, Diagnosis & Treatment  

MedlinePLUS

... type "leukemia" or "lymphoma" in the search box) Non-Hodgkin's Lymphoma Symptoms Swollen, painless lymph nodes in the neck, ... A lymph node biopsy is used to diagnose non-Hodgkin's lymphoma. Sometimes the diagnosis may be delayed because enlarged ...

54

Symptoms of Tickborne Illness  

MedlinePLUS

... symptoms include headache, fatigue, and muscle aches. With Lyme disease you may also experience joint pain. The severity ... disease and the patient's personal tolerance level. Rash: Lyme disease , southern tick-associated rash illness (STARI) , Rocky Mountain ...

55

Acne: Signs and Symptoms  

MedlinePLUS

... Signs, symptoms Who gets, causes Diagnosis, treatment Tips Acne scars Actinic keratosis Alopecia areata Atopic dermatitis Basal cell ... skin. When a nodule heals, it leaves an acne scar. Acne cyst An acne cyst forms when the ...

56

Depression symptoms during pregnancy  

Microsoft Academic Search

Summary  Pregnancy impacts common symptoms of major depressive disorder (MDD), such as energy, appetite, weight change, and sleep and\\u000a somatic complaints. However, it is not known whether the presentation of depression during pregnancy is different from that\\u000a at other times in women’s lives. This study compares the severity of symptoms of depression in 61 pregnant women with MDD\\u000a (PD), 50 nonpregnant

R. Manber; C. Blasey; J. J. B. Allen

2008-01-01

57

Contact Dermatitis: Signs and Symptoms  

MedlinePLUS

... treatments A - D Contact dermatitis Signs and symptoms Contact dermatitis: Signs and symptoms Allergic contact dermatitis : Testing ... these symptoms, you need immediate medical care. Allergic contact dermatitis This skin condition occurs when you have ...

58

Timing of Symptom Improvement After Parathyroidectomy for Primary Hyperparathyroidism  

PubMed Central

Background The timing of symptom improvement after parathyroidectomy for primary hyperparathyroidism (PHPT) has not been well characterized. Methods This prospective study involved administering a questionnaire to patients with PHPT who underwent curative parathyroidectomy over an 11-month period. The questionnaire evaluated the frequency of 18 symptoms of PHPT on a 5-point Likert scale, and was administered pre-operatively, and 1 week, 6 weeks, and 6 months postoperatively. Results Of 197 eligible patients, 132 (67%) participated in the study. The questionnaires were completed at a rate of 91%, 92%, and 86% at 1 week, 6 weeks, and 6 months post-operatively, respectively. The most commonly reported pre-operative symptoms were fatigue (98%), muscle aches (89%), and bone/joint pain (87%). Improvement in symptom severity occurred across all symptoms and was separated into three categories based on the timing of improvement. Fatigue and bone/joint pain demonstrated ‘Immediate Improvement’ (>50% of patients reporting improvement by post-operative week 1), whereas the majority of symptoms showed peak improvement at 6 weeks (‘Delayed Improvement’). Symptoms categorized as ‘Continuous Improvement’ were those showing progressive improvement up to 6 months post-operatively (polydipsia, headaches, and nausea/vomiting). Conclusions Symptom improvement was most prominent 6 weeks post-parathyroidectomy, though some symptoms showed continued improvement at 6 months. PMID:24238059

Murray, Sara E.; Pathak, Priya R.; Pontes, David S.; Schneider, David F.; Schaefer, Sarah C.; Chen, Herbert; Sippel, Rebecca S.

2013-01-01

59

Asthma Outcomes: Asthma Symptoms  

PubMed Central

Background Respiratory symptoms are commonly used to assess the impact of patient-centered interventions. Objective At the request of National Institutes of Health (NIH) institutes and other federal agencies, an expert group was convened to propose which measurements of asthma symptoms should be used as a standardized measure in future clinical research studies. Methods Asthma symptom instruments were classified as daily diaries (prospectively recording symptoms between research visits) or retrospective questionnaires (completed at research visits). We conducted a systematic search in PubMed and a search for articles that cited key studies describing development of instruments. We classified outcome instruments as either core (required in future studies), supplemental (used according to study aims and standardized), or emerging (requiring validation and standardization). This work was discussed at an NIH-organized workshop in March 2010 and finalized in September 2011. Results Four instruments (3 daily diaries, 1 for adults and 2 for children; and 1 retrospective questionnaire for adults) were identified. Minimal clinically important differences have not been established for these instruments, and validation studies were only conducted in a limited number of patient populations. Validity of existing instruments may not be generalizable across racial-ethnic or other subgroups. Conclusions An evaluation of symptoms should be a core asthma outcome measure in clinical research. However, available instruments have limitations that preclude selection of a core instrument. The working group participants propose validation studies in diverse populations, comparisons of diaries versus retrospective questionnaires, and evaluations of symptom assessment alone versus composite scores of asthma control. PMID:22386505

Krishnan, Jerry A.; Lemanske, Robert F.; Canino, Glorisa J.; Elward, Kurtis S.; Kattan, Meyer; Matsui, Elizabeth C.; Mitchell, Herman; Sutherland, E. Rand; Minnicozzi, Michael

2014-01-01

60

Bullying and PTSD Symptoms  

ERIC Educational Resources Information Center

PTSD symptoms related to school bullying have rarely been investigated, and never in national samples. We used data from a national survey to investigate this among students from grades 8 and 9 (n = 963). The prevalence estimates of exposure to bullying were within the range of earlier research findings. Multinomial logistic regression showed that…

Idsoe, Thormod; Dyregrov, Atle; Idsoe, Ella Cosmovici

2012-01-01

61

Symptom burden in cancer survivorship  

Microsoft Academic Search

Introduction  The subjective experience of cancer survivorship can be assessed by various patient-reported outcome (PRO) methods, including\\u000a measures of symptom burden and health-related quality of life (HRQOL). Symptom burden includes the presence and severity of\\u000a multiple symptoms and the level of distress caused by symptoms that go untreated or unrelieved. The concept of symptom burden\\u000a is more limited in scope than

V. Shannon Burkett; Charles S. Cleeland

2007-01-01

62

OGS improvements in 2012 in running the North-eastern Italy Seismic Network: the Ferrara VBB borehole seismic station  

NASA Astrophysics Data System (ADS)

The Centro di Ricerche Sismologiche (CRS, Seismological Research Centre) of the Istituto Nazionale di Oceanografia e di Geofisica Sperimentale (OGS, Italian National Institute for Oceanography and Experimental Geophysics) in Udine (Italy) after the strong earthquake of magnitude M=6.4 occurred in 1976 in the Italian Friuli-Venezia Giulia region, started to operate the North-eastern Italy Seismic Network: it currently consists of 17 very sensitive broad band and 18 simpler short period seismic stations, all telemetered to and acquired in real time at the OGS-CRS data centre in Udine. Real time data exchange agreements in place with other Italian, Slovenian, Austrian and Swiss seismological institutes lead to a total number of about 100 seismic stations acquired in real time, which makes the OGS the reference institute for seismic monitoring of North-eastern Italy. The south-western edge of the OGS seismic network (Fig. 1) stands on the Po alluvial basin: earthquake localization and characterization in this area is affected by the presence of soft alluvial deposits. OGS ha already experience in running a local seismic network in high noise conditions making use of borehole installations in the case of the micro-seismicity monitoring of a local gas storage site for a private company. Following the ML = 5.9 earthquake that struck the Emilia region around Ferrara in Northern Italy on 20 May 2012 at 02:03:53 UTC, a cooperation of Istituto Nazionale di Geofisica e Vulcanologia, OGS, the Comune di Ferrara and the University of Ferrara lead to the reinstallation of a previously existing very broad band (VBB) borehole seismic station in Ferrara. The aim of the OGS intervention was on one hand to extend its real time seismic monitoring capabilities toward South-West, including Ferrara and its surroundings, and on the other hand to evaluate the seismic response at the site. We will describe improvements in running the North-eastern Italy Seismic Network, including details of the Ferrara VBB borehole station configuration and installation, with first results.

Pesaresi, D.; Romanelli, M.; Barnaba, C.; Bragato, P. L.; Durì, G.

2014-07-01

63

Wiki'er og Wikipedia Finn Arup Nielsen  

E-print Network

Wiki'er og Wikipedia Finn °Arup Nielsen DTU Compute Technical University of Denmark April 23, 2013 #12;Wiki'er og Wikipedia Resum´e Wiki'er er efterh°anden alle vegne. De nyeste udviklinger muliggør struk- turering af data, s°a man kan opbygge sin egne specialiserede wiki-baserede database eller trække

64

Instrument for the Assessment of Prodromal Symptoms and States  

Microsoft Academic Search

\\u000a Certain constellations of prodromal symptoms have recently been shown to predict the onset of psychosis with a high degree\\u000a of accuracy, thus making treatment intervention in the prodromal phase more feasible scientifically and ethically. Here we\\u000a present a structured interview, the Structured Interview for Prodromal Symptoms (SIPS) and a severity scale, the Scale of\\u000a Prodromal Symptoms (SOPS), to identify operationally

Thomas H. McGlashan; Tandy J. Miller; Scott W. Woods; Ralph E. Hoffman; Larry Davidson

65

[Dissociative symptoms and sleep].  

PubMed

There is a widespread view among psychiatrists that dissociative experiences such as depersonalisation, derealisation, absorption, and psychogenic amnesia have a traumatic etiology. This view is subjected to a critical evaluation. We also discuss an alternative interpretation namely that dissociative experiences are caused by a labile sleep-wake rhythm. We evaluated this alternative view in two exploratory studies. In study 1 we looked at the relationship between the Dissociative Experience Scale (DES) and the Iowa Sleep Experiences Survey (ISES) and in study 2, we checked this relationship when the response bias was controlled for. Dissociative experiences (measured with the DES) correlated with the ISES. The correlation between DES and ISES remained completely intact even when we controlledfor response bias. Our findings show that dissociative symptoms are associated with typical sleep experiences such as nightmares and strange dreams. The association is not the by-product of the positive response bias which generally characterises persons with dissociative symptoms. PMID:16956084

Giesbrecht, T; Merckelbach, H

2006-01-01

66

Prader-Willi syndrom : hva er Prader-Willi syndrom, og hvilke utfordringer er typiske for syndromet? .  

E-print Network

??Prader-Willi syndrom skyldes en defekt på kromosom 15, og kommer klinisk til uttrykk gjennom blant annet hypotoni, spise-, puste- og trivselsproblemer, typiske ansiktstrekk, forsinket motorisk… (more)

Sæther, Pia

2011-01-01

67

[Depressive symptoms and sexuality].  

PubMed

The mutually reinforcing dyad of depressive symptoms and erectile dysfunction is scientifically established. The cure of depression improves sexual dysfunction (SD) and the treatment of SD induces improvement of depression. Most of anti-depressants induce negative sexual side effects that lead to non-compliance of these treatments. The knowledge of interrelation between depression, anti-depressants and sexuality is of great importance in clinical practice. PMID:25148948

Porto, Robert

2014-10-01

68

ADHD Symptoms and Subtypes: Relationship between Childhood and Adolescent Symptoms  

ERIC Educational Resources Information Center

A study aims to examine attention-deficit/hyperactivity disorder(ADHD) symptoms and subtypes in childhood and adolescence. The results conclude the persistence of ADHD from childhood to adolescence with specific symptoms contributing to persistent ADHD.

Hurtig, Tuula; Ebeling, Hanna; Taanila, Anja; Miettunen, Jouko; Smalley, Susan L.; McGough, James J.; Loo, Sandra K.; Jarvelin, Marjo-Riitta; Moilanen, Irma K.

2007-01-01

69

Signs and Symptoms of COPD  

MedlinePLUS

... Why is shortness of breath a symptom of COPD? Shortness of breath (or breathlessness ) is a common ... better or worse. Signs and Symptoms of COPD COPD MINI-SERIES #2 Chronic obstructive pulmonary disease (COPD) ...

70

Hidradenitis Suppurativa: Signs and Symptoms  

MedlinePLUS

... treatments E - H Hidradenitis suppurativa Signs and symptoms Hidradenitis suppurativa: Signs and symptoms Hidradenitis suppurativa : In its ... suppurativa: Who gets and causes. Learn more about hidradenitis suppurativa: Hidradenitis suppurativa Hidradenitis suppurativa: Who gets and ...

71

Herpes Simplex: Signs and Symptoms  

MedlinePLUS

... and treatments E - H Herpes simplex Signs, symptoms Herpes simplex: Signs and symptoms Herpes simplex: If a ... 6 weeks (the first outbreak) Learn more about herpes simplex: Herpes simplex Herpes simplex: Who gets and ...

72

Skin Cancer: Signs and Symptoms  

MedlinePLUS

... treatments Q - T Skin cancer Signs, symptoms Skin cancer: Signs and symptoms The most common warning sign ... appears in many ways. Learn more about skin cancer: Skin cancer Skin cancer: Who gets and causes ...

73

Organisk geokjemi og foraminiferfauna i midtre til øvre jura på Haltenbanken, med vekt på avsetningsmiljøet.  

E-print Network

??I dette hovedfagsarbeidet gir en stratigrafisk oversikt og faciestolkning av Melke- og Spekkformasjonen fra brønn 6507/7-5, basert på foraminiferanalyser kombinert med data fra organisk geokjemi,… (more)

Grønseth, Ole Tom

2004-01-01

74

Albertslund Kommune Marts 2009 Udvikling af milj-og energirigtig LED parklampe  

E-print Network

Albertslund Kommune Marts 2009 Udvikling af miljø- og energirigtig LED parklampe Albertslund nogle år siden blev jeg grebet af visionen om at skabe en LED gade-lampe med det halve strømforbrug og herunder energiforbruget. Projektet PSO 339-52 omfatter udvikling og design af en ny energieffektiv LED

75

Neuropsychiatric symptoms in Parkinson's disease  

PubMed Central

Neuropsychiatric symptoms are common in Parkinson's disease, even at the earliest stages, and have important consequences for quality of life and daily functioning, are associated with increased carer burden and increased risk for nursing home admission. In addition to cognitive impairment, a wide range of neuropsychiatric symptoms have been reported. In this paper, the epidemiology, clinical course, diagnosis, and management of some of the most common neuropsychiatric symptoms in PD are discussed: depression, anxiety, apathy, fatigue and psychotic symptoms. Although much is known regarding the prevalence and course of these symptoms, the empirical evidence for how to manage these symptoms is limited at best. There is thus an urgent need for systematic studies for the pharmacological and non-pharmacological management of these symptoms. PMID:19768724

Aarsland, D.; Marsh, L.; Schrag, A.

2009-01-01

76

Menopausal symptoms: is spirituality associated with the severity of symptoms?  

PubMed

The aim of this study was to explore whether spirituality was associated with menopausal symptoms. Menopausal symptoms, spirituality, health and menopausal status, and socio-demographic variables were assessed in a community sample of 710 peri- and postmenopausal women. A structural model was explored using structural equation modeling. The results evidence spirituality as a significant contributor regarding the severity of most menopausal symptoms. Among others, spirituality had a significant weight in depressive mood (? = -.414; p < .001), anxiety (? = -.308; p < .001), cognitive impairment (? = -.287; p < .001), aches/pain (? = -.148; p < .001), vasomotor (? = -.125; p = .005) and sexual symptoms (? = -.211; p < .001). Some socio-demographic variables, as well as perceived health, also predicted the menopausal symptoms' severity. Therefore, spirituality can have a positive impact on the menopausal symptoms' reporting. PMID:23471772

Pimenta, Filipa; Maroco, João; Ramos, Catarina; Leal, Isabel

2014-08-01

77

Prevalene of perimenstrual symptoms.  

PubMed Central

The purpose of this study was to determine the prevalence of perimenstrual symptoms (PMS) in a free-living population of US women and to determine if prevalence estimates varied with parity, contraceptive status, characteristics of the menstrual cycle, and selected demographic variables. We identified all households from a census listing for five southeastern city neighborhoods that offered variation in racial composition and socioeconomic status. We ascertained all households in which there was one nonpregnant woman between the ages of 18 and 35 years per household. Of the 241 eligible women, 179 (74 per cent) participated in the study. Trained interviewers administered the Moos Menstrual Distress Questionnaire (MDQ) and other demographic measures to women between March and July 1979. Symptoms with a prevalence greater than 30 per cent included weight gain, headache, skin disorders, cramps, anxiety, backache, fatigue, painful breasts, irritability, mood swings, depression, or tension. Only 2 to 8 per cent of women found most of these severe or disabling. The exceptions were severe cramps reported by 17 per cent of women and severe premenstrual and menstrual irritability by 12 per cent. Cramps, backaches, fatigue, and tension were most prevalent during the menstruum; weight gain, skin disorders, painful breasts, swelling, irritability, mood swings, and depression were more prevalent in the premenstruum. Parity, oral contraceptive use, age, employment, education, and income were negatively associated with selected PMS. Use of an IUD, having long menstrual cycles, long menstrual flow, or heavy menstrual flow, and being able to predict the next period were positively associated with selected PMS. Race had both positive and negative effects on PMS. PMID:6889817

Woods, N F; Most, A; Dery, G K

1982-01-01

78

Pain and other symptoms in cancer survivors.  

PubMed

Pain is common in cancer survivors. Long-term pain, often of neuropathic origin, is common after operations, radiotherapy, and chemotherapy. Pain and other concomitant symptoms and side effects should be assessed with validated and reliable scales and questionnaires. Cancer survivors with severe pain should be seen by a pain specialist. Multidisciplinary rehabilitation and individualized pain management may improve quality of life in cancer survivors. Four case reports are presented to illustrate this. PMID:24801977

Westerling, Dagmar

2014-06-01

79

Indoor environmental exposures and symptoms.  

PubMed Central

The label "sick building syndrome" is often used to imply the absence of a physiologic basis for symptoms in the built environment. Although building-related illness is widely recognized but considered rare, several well-studied mechanisms may be responsible for many symptoms in buildings. These mechanisms do not explain why some individuals perceive disability. Until researchers distinguish physiologic mechanisms from other aspects of disease and study them systematically, poorly defined symptoms will remain poorly understood. The disability associated with such symptoms and syndromes, not the physiology, is the primary interest and generates controversy. PMID:12194903

Hodgson, Michael

2002-01-01

80

Menopause. How Exercise Mitigates Symptoms.  

ERIC Educational Resources Information Center

During menopause and the climacteric, women experience many changes that can affect nearly every organ system and cause psychological symptoms. This article reviews the specific changes and explains how exercise can address each symptom; outlines a practical approach physicians can use to help menopausal patients improve their quality of life. (SM)

Hargarten, Kathleen M.

1994-01-01

81

COMPARATIVE DYNAMICS OF FOUR SMOKING WITHDRAWAL SYMPTOM SCALES  

PubMed Central

Aims Examine the association of person-specific trajectories of withdrawal symptoms of urge-to-smoke, negative affect, physical symptoms, and hunger during the first 7 days after smoking cessation with abstinence at end of treatment (EOT) and 6 months. Design Hierarchical Linear Modeling (HLM) was used to model person-specific trajectory parameters (level, slope, curvature and volatility) for withdrawal symptoms. Setting University-based smoking cessation trials. Participants Treatment seeking smokers in clinical trials of transdermal nicotine versus nicotine spray (n=514) and bupropion versus placebo (n=421) Measurements Self-reported withdrawal symptoms for 7 days after the planned quit date, and 7 day point prevalence and continuous abstinence at EOT and 6 months. Findings In regressions that included trajectory parameters for one group of withdrawal symptoms, both urge-to-smoke and negative affect were predictive of abstinence while physical symptoms and hunger were generally not predictive. In stepwise regressions that included the complete set of trajectory parameters across withdrawal symptoms (for urge-to-smoke, negative affect, physical symptoms, and hunger), with a single exception, only the trajectory parameters for urge-to-smoke were predictive. Area under the Receiver Operator Characteristic curve was 0.594 for covariates alone, and 0.670 for covariates plus urge-to-smoke trajectory parameters. Conclusion Among a number of different withdrawal symptoms (urge-to-smoke, negative affect, physical symptoms, and hunger) urge-to-smoke trajectory parameters (level, slope, and volatility) over the first 7 days of smoking cessation show the strongest prediction of both short and long term relapse. Other withdrawal symptoms increase the predictive ability by negligible amounts. PMID:22321019

Javitz, Harold S.; Lerman, Caryn; Swan, Gary E.

2012-01-01

82

Gastrointestinal Symptoms in Morbid Obesity  

PubMed Central

Background: Several reports have shown an increased prevalence of gastrointestinal (GI) symptoms in obese subjects in community-based studies. To better understand the role of the GI tract in obesity, and because there are limited clinic-based studies, we documented the prevalence of upper and lower GI symptoms in morbidly obese individuals in a clinic setting. Objective: The aim of our study was to compare the prevalence of GI symptoms in morbidly obese individuals in a weight management clinic with non-obese individuals with similar comorbidities as morbidly obese individuals in an Internal Medicine clinic. Methods: Class II and III obese patients BMI >35?kg/m2 (N?=?114) and 182 non-obese patients (BMI <25?kg/m2) completed the GI symptoms survey between August 2011 and April 2012 were included in this study. The survey included 24 items pertaining to upper and lower GI symptoms. The participants rated the frequency of symptoms as absent (never, rarely) or present (occasionally, frequently). The symptoms were clustered into five categories: oral symptoms, dysphagia, gastroesophageal reflux, abdominal pain, and bowel habits. Responses to each symptom cluster were compared between obese group and normal weight groups using logistic regression. Results: Of the 24 items, 18 had a higher frequency in the obese group (p?symptoms: any oral symptom (OR?=?2.3, p?=?0.0013), dysphagia (OR 2.9, p?=?0.0006), and any gastroesophageal reflux (OR 3.8, p?symptoms: any abdominal pain (OR?=?1.7, p?=?0.042) and altered bowel habits (OR?=?2.8, p?symptoms in morbidly obese patients when compared to non-obese subjects. PMID:25593922

Huseini, Mustafa; Wood, G. Craig; Seiler, Jamie; Argyropoulos, George; Irving, Brian A.; Gerhard, Glenn S.; Benotti, Peter; Still, Christopher; Rolston, David D. K.

2014-01-01

83

Af projektleder, lektor, ph.d. Kjeld Rasmusen og projektkoordi-nator, lektor, ph.d. Ole Mertz, Institut for Geografi og Geologi,  

E-print Network

321 Af projektleder, lektor, ph.d. Kjeld Rasmusen og projektkoordi- nator, lektor, ph.d. Ole Mertz, Institut for Geografi og Geologi, Københavns Universitet Landbaseret (Salomonøerne) Deltagere Ole Mertz: Ole Mertz #12;323 Formidlingsmæssig status Resultaterne vil blive formidlet på følgende måder: 1. En

84

Three Years of on Orbit ISS Oxygen Generation System Operation 2007-2010  

NASA Technical Reports Server (NTRS)

The International Space Station (ISS) United States Orbital Segment (USOS) Oxygen Generation System (OGS) has accumulated 240 days of continuous operation at varied oxygen production rates within the US Laboratory Module (LAB) since it was first activated in July 2007. OGS relocated from the ISS LAB to Node 3 during 20A Flight (February 2010). The OGS rack delivery was accelerated for on-orbit checkout in the LAB, and it was launched to ISS in July of 2006. During the on-orbit checkout interval within the LAB from July 2007 to October 2008, OGS operational times were limited by the quantity of feedwater in a Payload Water Reservoir (PWR) bag. Longer runtimes are now achievable due to the continuous feedwater availability after ULF2 delivery and activation of the USOS Water Recovery System (WRS) racks. OGS is considered a critical function to maintaining six crew capability. There have been a number of failures which interrupted or threatened to interrupt oxygen production. Filters in the recirculation loop have clogged and have been replaced, Hydrogen sensors have fallen out of specifications, a pump delta pressure sensor failed, a pump failed to start, and the voltage on the cell stack increased out of tolerance. This paper will discuss the operating experience and characteristics of the OGS, as well as operational issues and their resolution.

Diderich, Greg S.; Polis, Pete; VanKeuren, Steven P.; Erickson, Bob

2010-01-01

85

Neuropsychiatric symptoms and celiac disease  

PubMed Central

Background Neuropsychiatric symptoms may represent an atypical manifestation of celiac disease that occur before a gastroenterological diagnosis is made. Some studies suggest that a gluten-free diet is effective in treating the depression, anxiety, and neurological complications associated with celiac disease. Method The article describes the case of a patient suffering from chronic, treatment-resistant symptoms of depression and anxiety. The diagnosis of celiac disease and introduction of an elimination diet caused a significant improvement in mental state and everyday functioning in the presenting patient. Conclusion The presence of persistent anxiety and depressive symptoms, with a poor reaction to pharmacological treatment, indicates a need to identify somatic reasons for the underlying condition. It is important to remember that celiac disease can occur at any age, not only in childhood. The presence of this somatic cause of persistent depressive and anxiety symptoms should be considered in the diagnostic process in adults. PMID:25342904

Urban-Kowalczyk, Ma?gorzata; Œmigielski, Janusz; Gmitrowicz, Agnieszka

2014-01-01

86

Respiratory Syncytial Virus (RSV): Symptoms  

MedlinePLUS

... enabling JavaScript. Respiratory Syncytial Virus (RSV) Skip Content Marketing Share this: Main Content Area Symptoms Most children ... that can be heard High fever Cough with green or yellow mucus back to top Last Updated ...

87

Know the symptoms. Take action.  

E-print Network

after you call 9­1­1. Medicines you are taking: ______________________________ ______________________________ ______________________________ Medicines you are allergic to Warning Symptoms Chest Pain or Discomfort Discomfort in the center or left side of the chest that lasts

Bandettini, Peter A.

88

Symptoms of Lewy Body Dementia  

MedlinePLUS

Lewy body dementia symptoms and diagnostic criteria Every person with LBD is different and will manifest different degrees of the following ... an umbrella term for two related clinical diagnoses, dementia with Lewy bodies and Parkinson's disease dementia. The ...

89

JAMA Patient Page: Vaginal Symptoms  

MedlinePLUS

... 20% of vaginal symptoms are caused by trichomoniasis. • Vaginal candidiasis —Also known as a yeast infection , this condition is caused by an overgrowth of fungus that occurs naturally in the vagina and accounts for about 20% to 25% of ...

90

TBI Symptoms, Diagnosis, Treatment, Prevention  

MedlinePLUS

... Home Current Issue Past Issues Cover Story: Traumatic Brain Injury TBI Symptoms, Diagnosis, Treatment, Prevention Past Issues / Fall ... lucky in my ongoing recovery from the traumatic brain injury I suffered in Iraq." —Bob Woodruff Treatment Immediate ...

91

21RIS N Y T 4/01 Studier af strukturerne i planter og  

E-print Network

21RIS� N Y T 4/01 Studier af strukturerne i planter og mikroorganismer har traditionelt været- derne for at udføre studier over tid af processer i celler og væv. Den hastige udvikling inden for genteknologi og optisk analyse sætter nu forskerne i stand til at gennemføre studier, der har en begrænset

92

Undervisning og lring med sociale medier/web 2.0  

E-print Network

17-05-2010 1 Undervisning og læring med sociale medier/web 2.0 Phd Studerende, MA Lillian Buus lillian@hum.aau.dk Aalborg Universitet Dagsorden · Kort præsentation · Hvad er sociale medier og web 2.0? · Netværksrelationer i sociale medier · Web 2.0 og sociale medier i et læringsperspektiv · Hvordan designer vi læring i

Hansen, René Rydhof

93

Psychiatric symptoms in vertiginous patients.  

PubMed

Backgrounds: Psychiatric comorbidity is common in vertiginous patients. The risk of psychiatric disorder is increased in patients with previous mental problems, but earlier mentally healthy may develop symptoms as well. Especially in chronic phase of vertigo, psychological factors have a significant role in the morbidity. Aims: The aim of this study was to evaluate the prevalence of psychiatric problems in vertiginous patients in a community sample. Methods: A prospective evaluation of psychiatric symptoms based on self-rating scales [Beck Depression Inventory (BDI), Zung Anxiety Scale (SAS), DSM-IV and ICD-10 Personality Questionnaire (DIP-Q)] in a community sample of 100 vertiginous subjects in the Academic Tertiary Otolaryngology Department at the Helsinki University Hospital, Finland. Results: The prevalence of any psychiatric problem was 68% (68 patients); 19% had depressiveness and 12% symptoms of anxiety. Altogether 63 (63%) patients met the criteria of personality disorder. The most prevalent personality disorder was obsessive-compulsive (46 patients). Personality disorder alone seems not to affect functional capacity and is of importance only when comorbid with symptoms of anxiety and depression. The prevalence of psychiatric symptoms did not correlate with severity of vertigo symptoms or other co-occurring diseases. Conclusions: The prevalence of any psychiatric symptoms was high among vertiginous patients. In the chronic phase of vertigo, it seems that vertigo symptoms themselves do not influence on subjective feelings of debilitation. Psychiatric disorders worsen the clinical picture of vertigo along a more debilitating and disabling course. Psychiatric differential diagnoses should accompany the neuro-otology diagnostic procedure in patients with a chronic state of vertigo and greater disability. PMID:25394373

Ketola, Sirpa; Havia, Mari; Appelberg, Björn; Kentala, Erna

2014-11-14

94

What Are the Symptoms of Endometriosis?  

MedlinePLUS

... Publications En Español What are the symptoms of endometriosis? Skip sharing on social media links Share this: ... symptoms, may cause these endometriosis symptoms to continue. Endometriosis-Related Pain Researchers know that pain is a ...

95

Materialeforsker fra Ris tog springet og startede verdens frste virksom-  

E-print Network

friction stir welding - svejsning ved hjælp af omrørings-friktion - en ny teknolo- gi, som han tror så, ville det ikke have gjort den store forskel. Med friction stir welding er støj, røg og kraftigt lys fra flyalumini- um profiler. Med friction stir welding kan man dels slippe for nitter, dels for at bruge det

96

Stone symptoms and urinary deposits.  

PubMed

There is a general belief among the public and clinicians that urinary stone problem is always associated with symptoms like pain, dysuria and haematuria. Many patients stop medical treatment when they are symptom free and return with excruciating pain, dysuria and haematuria either alone or in combination. The objective of this study was to determine stone activity in an individual patient by assessing the urinary deposits at the time of the visit to the stone clinic and correlate with the presence or absence of symptoms at that time. 418 patients who attended the stone clinic in 2007 with proved urinary stone disease, including stone, colic and crystalluria, were studied. Presence or absence of symptoms at the time of presentation was recorded. Minimum of two samples of urine was collected (early morning and random) to assess the presence and extent (1-5) of urinary deposits namely red blood cells (RBC), pus cells (PC), calcium oxalate monohydrate (COM), calcium oxalate dihydrate (COD), uric acid and phosphate. The scores obtained were correlated with the presence or absence of symptoms by logistic regression. Of the 418 patients studied, 238 had symptoms and 180 had no symptoms. The total score of the deposits of patients with symptoms was 1,215 with a mean of 3.39 per patient against the score of 350 in the patients without symptoms with a mean of 2.99. This difference was not statistically significant. The total values and mean scores of the urinary deposits of all patients grouped together were RBC 561 (3.51), PC 434 (3.29), COM 177 (3.34), COD 237 (3.25), phosphate 113 (3.23) and uric acid 43 (1.95). Comparison of the total values and mean scores of the deposits of the patients with and without symptoms showed the variations as RBC 428 (3.51) versus 133 (3.5) PC 341 (3.38) versus 93 (3.0), COM 143 (3.25) versus 34 (3.78), COD 190 (3.88) versus 47 (1.96), phosphate 76 (3.3) versus 37 (3.1) and uric acid/ammonium urate 37 (1.95) versus 6 (2.0). Of these, the RBC, PC, uric acid and phosphates were not significantly different between the two groups. However, the presence of COD was significantly more in patients with symptoms (P < 0.05) and COM was significantly more in patients without symptoms (P < 0.05). It is concluded that the presence or absence of symptoms does not alter the presence and extent of urinary deposits significantly in the urinary stone patients. COD was more in symptomatic patients and COM was more in the asymptomatic patients. This contrast could be due to the morphology of the COD crystal which is dipyramidal and produces injury to urolthelium whereas COM is dumbbell shaped and produces lesser injury and lesser symptoms. PMID:19888570

Fazil Marickar, Y M; Salim, Abiya; Vijay, Adarsh

2010-02-01

97

Symptom Identification in the Chronically Critically Ill  

PubMed Central

Ascertaining the symptom experience of chronically critically ill (CCI) patients is difficult due to communication impairment and fluctuations in patient cognition and physiological conditions. The use of checklist self report ratings is hampered by the inability of most CCI patients to respond verbally to symptom queries. In addition to the communication problems caused by mechanical ventilation, the apparently diverse idioms of symptom expression add to the potential for miscommunication regarding symptom experience. Although patient communication impairment is a major barrier to symptom identification, symptom assessment and treatment are fundamental components of nursing care for CCI. This paper reviews and describes the unique constellation of symptoms experienced by many critically ill patients. We report our observations of symptom communication among CCI patients and nurses and discuss inconsistency in the language of symptom expression among nurses and patients. Clinically applicable strategies to improve nurse-patient symptom communication and suggestions for refinement of symptom assessment in chronic critical illness are provided. PMID:20118706

Campbell, Grace B.; Happ, Mary Beth

2010-01-01

98

The measurement of menstrual symptoms  

PubMed Central

This study examined the factor structure of the Menstrual Symptom Questionnaire (MSQ) in a sample of 210 adolescent girls (11–17 years). Such an examination has not been carried out with an adolescent sample. In addition, the definitions of menstrual disorders have evolved since the creation of the MSQ. Exploratory factor analysis supported a three factor structure indicating abdominal pain, negative affect/somatic complaints, and back pain. Partial correlations indicated all three MSQ factors were correlated with depressive symptoms, but only the negative affect factor was correlated with trait anxiety. Future research should explore potential associations in multiple areas of functioning as menstrual symptoms may alter healthy developmental processes during adolescence. PMID:19786516

NEGRIFF, SONYA; DORN, LORAH D.; HILLMAN, JENNIFER B.; HUANG, BIN

2015-01-01

99

Som flere andre lande i Asien og Sydamerika nsker Sydkorea at opbygge effektive syste-  

E-print Network

kan forfalskes. Efter alt at dømme bliver løsningen et smart- card, som firmaet Optilink har kortet og læse dem, og en, hvor brugeren kun kan udlæse data. Især den sidste udgave ventes solgt i stor

100

32 Robust og bredygtig bioenergi september 2012 Af Brian Vad Mathiesen, David  

E-print Network

transport og en lille stigning i el- forbruget. I 1980 brugte vi mindre end 150 PJ til transport, men det er for person- og gods- transport. I referencescenariet har vi valgt at medregne al transport, der har tilknyt scenarier, der er lavet, men det bety- der samtidig, at arbejdet ikke er helt sammenligneligt med andre

Schaltz, Erik

101

Slutrapport for PSO 337-068 Udvikling af LED lyskilder og lamper  

E-print Network

Slutrapport for PSO 337-068 Udvikling af LED lyskilder og lamper Carsten Dam-Hansen, Paul Michael-068 Udvikling af LED lyskilder og lamper Risø-R-1606(DA) April 2007 Abstract (in English) (max. 2000 char.): This report is the final and concluding report on the research and development project "Development of LED

102

Hvad skal vi med teknologisk fremsyn fremover? 7 rs erfaring og perspektiver for fremtiden  

E-print Network

Internationale netværk · ESTO ­ European Science and Technology Observatory · COST A22 ­ Foresight Methodologies Foresight Forum · Expectations netværk "Støtteforskning" · Fremsyn og science fiction · Scenarier og into the longer-term future of science, technology, the economy and society with the aim of identifying the areas

103

CAT er en kompetent og risikovillig med-spiller nr hjteknologisk forskning skal  

E-print Network

CAT er en kompetent og risikovillig med- spiller når højteknologisk forskning skal omsættes til holdbar forretning. CAT er en forskerpark der drives i samarbej- de mellem Danmarks Tekniske Universitet forskning og udvikling i samar- bejde med de tre institutioners forskere. �n af virksomhederne i CAT er

104

RESPONDING TO FLU-LIKE SYMPTOMS  

E-print Network

RESPONDING TO FLU-LIKE SYMPTOMS If you start exhibiting flu-like symptoms, call SU Health Services because of flu-like symptoms: Tell your RA. Tell your roommate (if you have one). Socially distance in their rooms or apartments because of flu-like symptoms, the sick meal policy is being expanded. When students

McConnell, Terry

105

Arbeidskapasitet, fatigue og helserelatert livskvalitet for pasienter med Myalgisk Encefalopati eller Kronisk Utmattelses Syndrom før og etter trening med Qigong : En randomisert kontrollert studie.  

E-print Network

??Formål: Hensikten med denne studien var å undersøke arbeidskapasitet, fatigue(tretthet) og helserelatert livskvalitet hos en gruppe personer diagnostisert med CFS/ME sammenlignet med referanse materiale fra… (more)

Dybwad, Marianne Holth

2007-01-01

106

Schizophrenia and gastroesophageal reflux symptoms  

PubMed Central

Background: Psychological factors and psychiatric disorders play a role in a variety of gastrointestinal illnesses, including esophageal diseases. Aim: The aim of the present study was to evaluate the frequency of gastroesophageal reflux disease symptoms in patients with schizophrenia in Turkey. Patients and Methods: Ninety-eight patients with schizophrenia and one hundred control individuals were enrolled in the study, which was undertaken at the Manisa State Hospital for Mental Health and Neurological Disorders and Celal Bayar University Gastroenterology Department. Case and control subjects alike underwent 30–45 min oral interviews conducted by a designated study coordinator (E.K.). The coordinator gathered information about demographic characteristics, social habits, and a large variety of symptoms suggestive of reflux disease or other gastrointestinal conditions. Results: In terms of reflux symptoms, cough was the only significant association in schizophrenic patients than controls. Heartburn and regurgitation were more frequent in schizophrenic patients who smoked than in controls who were smokers. However, the prevalence of reflux symptoms in cigarette smokers versus nonsmoker patients with schizophrenia was similar. Heartburn and/or regurgitation occurred more frequently in patients with schizophrenic than controls with alcohol use. Conclusions: Psychiatric disorders might indirectly affect esophageal physiology through increased consumption of alcohol and nicotine.

Kasap, Elmas; Ayer, Ahmet; Bozo?lan, Hümeyra; Ozen, Cigdem; Eslek, Ilhan; Yüceyar, Hakan

2015-01-01

107

Strling og Helse Vi lever i et hav av strling. Det er g-strling fra bakken, kosmisk strling ovenfra, radon i luften og radioaktiv-  

E-print Network

Stråling og Helse Vi lever i et hav av stråling. Det er g-stråling fra bakken, kosmisk stråling du kanskje flytte til et sted uten stråling? Radioaktivitet fra bakken Kosmisk stråling Radon radon og lungekreft) Radioaktivitet fra bakken Helt fra jorda ble dannet har det vært radioaktive

Sahay, Sundeep

108

Symptoms  

MedlinePLUS

... Rights Employment Discrimination Health Care Professionals Law Enforcement Driver's License For Lawyers Food & Fitness Home Food MyFoodAdvisor ... IQhydr8 Keep your Hydration on Track and Give Back. Living W/ Diabetes: Are You a Teen with ...

109

Chronic rhinosinusitis: correlation of symptoms with computed tomography scan findings  

PubMed Central

Introduction Symptomatology, nasal endoscopy and Computerised Tomographic (CT) scan have been used to diagnose chronic rhinosinusitis. The value of disease severity score in the assessment of chronic rhinosinusitis has not been well investigated. Hence, this study aims to correlate the pre-operative symptom severity score as well as overall disease severity scoreof patients with chronic rhinosinusitis with CT scan scores. Methods This is a prospective study of 60 patients diagnosed clinically with chronic rhinosinusitis. Each patientsubjectively assessed his/her presenting symptoms and severity of disease on a visual analogue scale. The patients had CT scan of the paranasal sinuses which were graded and scored using Lund-Mackay grading system. The correlation study between severity of symptoms/disease severity and CT scores was performed. The level of statistical significance was considered at p < 0.05 and confidence interval at 95%. Results All patients had more than one symptom with mean symptom severity scores highest for nasal discharge and nasal obstruction. There was a significant correlation between CT scores and nasal discharge (r = -0.132; p = 0.03)and nasal obstruction (r = 0.193; p = 0.049). No correlation with other symptoms. There wasno correlation between the overall disease severity scores and the Lund-Mackay CT scores (r = 0.195; p = 0.6). Conclusion This study showed that CT scan scores can help clinicians to predict severity of symptom for nasal obstruction and discharge but not for other symptoms of chronic rhinosinusitis. However, there was no association of CT score with the overall disease severity score. PMID:25368729

Amodu, Enema Job; Fasunla, Ayotunde James; Akano, Aliu Oyebamiji; Daud Olusesi, Abiodun

2014-01-01

110

Symptom severity and distress in advanced cancer.  

PubMed

We determined the relationship between symptom severity and distress for multiple cancer symptoms, and examined patient demographic influences on severity and distress in advanced cancer. A Cochran-Armitage trend test determined whether symptom distress increased with severity. Chi-square, Fisher's exact test and logistic regression analysis examined moderate/severe ('clinically important') and distressful symptoms by age (65), gender, primary site group, and ECOG performance status. Forty-six symptoms were analyzed in 181 individuals. More than 50% of individuals with clinically important symptoms rated them as distressful. The median percentage of individuals with mild but still distressful symptoms was 25%, with a range of 0% (bad dreams) to 73% (sore mouth). In both univariate and multivariate analysis, younger (symptoms (only anxiety was more frequently distressful to older individuals). Clinically important symptoms and two of those considered distressful varied by primary site group. After control for severity, symptom distress did not differ by primary site group. The prevalence of distress increased with greater symptom severity. Younger individuals, those with poor performance status, and females had greater symptom severity and distress. Mild symptoms were often distressful. After adjustment for severity, age, gender, and performance status all influenced symptom distress. PMID:20015920

Kirkova, Jordanka; Walsh, Declan; Rybicki, Lisa; Davis, Mellar P; Aktas, Aynur; Tao Jin; Homsi, Jade

2010-04-01

111

Evaluation of a gastrointestinal symptoms questionnaire.  

PubMed

Questionnaires are widely used instruments to monitor gastrointestinal (GI) symptoms. However, few of these questionnaires have been formally evaluated. We sought to evaluate our GI symptoms questionnaire in terms of clarity and reproducibility. Primary care patients referred for open access Helicobacter pylori urea breath testing reported GI symptoms (type+severity) and demographic information by written questionnaire. In an interview, patients gave a personal description of the meaning of the GI symptoms on the questionnaire. Patients' descriptions of GI symptoms were compared with current definitions. Symptom severity scores were compared before and after, interview versus questionnaire. Of the 45 patients included, 19 (42%) described all symptoms correctly, whereas 17 (38%) described one symptom incorrectly. None of the patients made more than three mistakes. Regurgitation was the most common incorrectly described symptom (16 patients [36%]), whereas the other individual symptoms were well explained. Symptom severities before the interview, after the interview and reported by questionnaire (mean value+/-SEM) were 2.1 +/- 0.2, 2.1 +/- 0.2, and 1.5 +/- 0.2 points on a 7-point Likert scale (0-6), respectively. Mean severity reported by interview (95% CI) was 1.4 (1.3-1.5) times higher than reported by questionnaire (P < .05). In conclusion, the GI symptom questionnaire is understandable and has good reproducibility for measuring the presence of GI symptoms, although symptom severity is consistently rated higher when reported by interview. PMID:16927133

Bovenschen, H J; Janssen, M J R; van Oijen, M G H; Laheij, R J F; van Rossum, L G M; Jansen, J B M J

2006-09-01

112

The Impact of Depressive Symptoms in Adults with ADHD Symptoms on Family Function and ADHD Symptoms of Their Children  

PubMed Central

Objective People with attention-deficit/hyperactivity disorder (ADHD) exhibit considerable impairment in social, academic, or occupational functioning. The present study aimed to examine the patterns of associations between ADHD symptoms, depression, and family functioning. Methods The sample consisted of 1,022 adults randomly selected from a district in Seoul, South Korea. Several self-assessment scales were utilized to rate ADHD symptoms (both past and current), current symptoms of depression, and level of family functioning. ADHD symptoms in the children of these participants were also assessed. Pearson's correlation and multiple linear regression analyses were performed; structural equation modeling (SEM) was conducted to determine the best fitting model. Results Adult ADHD symptoms were positively associated with depressive symptoms. Depressive symptoms, in turn, mediated the relationship between adult ADHD symptoms and cohesion among family members. In addition, depressive symptoms mediated the relationship between adult ADHD symptoms and their children's ADHD symptoms. Conclusion The relationship between adult ADHD symptoms and family dysfunction may be influenced by depressive symptoms. When treating ADHD in adults, clinicians should pay attention to the presence or absence of depression. PMID:24843366

Hong, Soon-Beom; Lee, Jong-Ha; Chun, Duk Hee; Shin, Min-Sup; Yoo, Hee-Jeong; Kim, Boong-Nyun; Cho, Soo-Churl

2014-01-01

113

Irrational beliefs and bulimia symptoms  

Microsoft Academic Search

The psychological correlates of bulimia include affective disorder and emotional liability. In addition, emotional liability appears to precipitate binge-purge episodes. It has been proposed that emotional liability is a function of irrational beliefs regarding personal performance, interpersonal relationships and self-control. Irrational beliefs and bulimia symptoms were assessed with psychometrically valid self-report measures. Correlational analyses showed that the irrational beliefs of

Jeffrey M. Lohr; Donna L. Parkinson

1989-01-01

114

Erste Symptome des Organizational Burnout  

Microsoft Academic Search

\\u000a Die ersten Anzeichen des Organizational Burnout sind weder von der betroffenen Organisation oder Institution noch von einem\\u000a externen Analysten zu erkennen. So wenig, wie beispielsweise Diabetes. Diese Krankheit kann jahrzehntelang unbemerkt verlaufen.\\u000a Die ersten Symptome sind in der Regel schwach ausgeprägt. Nicht einmal die Hälfte der Bluthochdruckerkrankungen wird erkannt\\u000a – und von diesen wird nur die Hälfte behandelt, weil es

Gustav Greve

115

Associations between miscellaneous symptoms and symptom dimensions in adults with obsessive-compulsive disorder.  

PubMed

Obsessive-compulsive disorder (OCD) is a debilitating psychiatric condition with a heterogeneous array of obsessions and compulsions. Although factor analytic studies have identified symptom dimensions comprising the clinical presentation of OCD, many frequently reported miscellaneous symptoms are not considered in factor analytic studies because they do not fit conceptually within a particular symptom category, despite being functionally related. In the present study, we examined the associations between miscellaneous symptoms and OCD symptom dimensions in a sample of 111 adults with OCD. Overall, most miscellaneous symptoms were associated with one or more symptom dimensions in previously identified four- (14 of the 22 symptoms) and five-factor models (12 of the 22 symptoms). In both models, Contamination/Cleaning was the only dimension not related to any miscellaneous symptom. The present results provide information about which miscellaneous symptoms may be related to particular symptom dimensions, which will assist in clinical evaluations and help planning behavioral psychotherapy (e.g., hierarchy development). PMID:18350397

Storch, Eric A; McNamara, Joseph; Jordan, Cary; Marien, Wendi E; Jacob, Marni L; Murphy, Tanya K; Goodman, Wayne K; Geffken, Gary R

2008-04-01

116

Decoloration of orange G (OG) using electrochemical reduction.  

PubMed

The electrocatalytic hydrogenation of Orange G is investigated using spectrophotometric experiments in laboratory cells. The working electrode consists of a thin grid coated with a layer of nickel in which fine particles of Raney nickel are dispersed. The optimal conditions of decoloration are as follows: basic pH, 0.05 g/L of dye concentration and 0.05 A of current density. Under these conditions, the OG decoloration efficiency reached 100% after only 1800 s of reaction. The observed values of the maximum absorbance in the spectra of the reaction mixture fitted well the polynomials of the fifth degree with respect to reaction time. The initial degradation rate of the dye is obtained easily as the differential coefficient of the functions at initial time. The degradation rate of the dye in the initial stage of the reaction is given by the first-order rate equation. The instantaneous current efficiency was calculated and the results indicated that cathodic reduction was the main contributor to the decoloration of OG. Direct cathodic reduction ofazo dyes allows decolorization of intensively coloured textile wastewater without addition of chemicals or formation of sludge. The technique is of particular interest for the treatment of concentrated dye baths. The effect of current density, dye concentration, and concentration and nature of the supporting electrolyte on the reduction of the Orange G are reported. PMID:22720437

Khenifi, Aicha; Bouberka, Zohra; Hamani, Houari; Illikti, Hocine; Kameche, Mostefa; Derriche, Zoubir

2012-01-01

117

Mindfulness Is Associated with Fewer PTSD Symptoms, Depressive Symptoms, Physical Symptoms, and Alcohol Problems in Urban Firefighters  

ERIC Educational Resources Information Center

Objective: This study investigated the association between mindfulness, other resilience resources, and several measures of health in 124 urban firefighters. Method: Participants completed health measures of posttraumatic stress disorder (PTSD) symptoms, depressive symptoms, physical symptoms, and alcohol problems and measures of resilience…

Smith, Bruce W.; Ortiz, J. Alexis; Steffen, Laurie E.; Tooley, Erin M.; Wiggins, Kathryn T.; Yeater, Elizabeth A.; Montoya, John D.; Bernard, Michael L.

2011-01-01

118

Mindfulness Is Associated With Fewer PTSD Symptoms, Depressive Symptoms, Physical Symptoms, and Alcohol Problems in Urban Firefighters  

Microsoft Academic Search

Objective: This study investigated the association between mindfulness, other resilience resources, and several measures of health in 124 urban firefighters. Method: Participants completed health measures of posttraumatic stress disorder (PTSD) symptoms, depressive symptoms, physical symptoms, and alcohol problems and measures of resilience resources including mindfulness, optimism, personal mastery, and social support. The Mindful Awareness and Attention Scale (MAAS; Brown &

Bruce W. Smith; J. Alexis Ortiz; Laurie E. Steffen; Erin M. Tooley; Kathryn T. Wiggins; Elizabeth A. Yeater; John D. Montoya; Michael L. Bernard

2011-01-01

119

What Are Common Symptoms of Down Syndrome?  

MedlinePLUS

... Publications En Español What are common symptoms of Down syndrome? Skip sharing on social media links Share this: Page Content The symptoms of Down syndrome vary from person to person, and people with ...

120

Introduction to Symptoms of Eye Disorders  

MedlinePLUS

... Resources for Help and Information The One-Page Merck Manual of Health Medical Terms Conversion Tables Manuals ... the Eyes Vision Loss, Sudden Other Eye Symptoms Merck Manual > Patients & Caregivers > Eye Disorders > Symptoms of Eye ...

121

Exercise-Associated Symptoms in Triathletes.  

ERIC Educational Resources Information Center

A survey of 110 triathletes was made to identify symptoms experienced during triathlon activities, to determine factors affecting the symptoms, and to find out if symptoms were specific to the athlete or to the event. Results are discussed. (Author/MT)

Sullivan, Stephen N.

1987-01-01

122

Depressive symptoms associated with sexual assault  

Microsoft Academic Search

The Beck Depression Inventory was used to assess depressive symptoms in 178 sexual assault survivors and 50 control subjects who had never been sexually assaulted. The sexual assault survivors reported significantly more depressive symptoms than the control subjects, and further analyses strongly suggested that the depressive symptoms were caused by the sexual assault. Investigation of the relationships between depression scores

Judith V. Becker; Linda J. Skinner; Gene G. Abel; Roz Axelrod; Eileen C. Treacy

1984-01-01

123

Rheumatic symptoms in autoimmune thyroiditis.  

PubMed

Autoimmune thyroiditis (ATD) is generally regarded as a classic example of single organ autoimmunity with a high association with endocrine thyroid disorders. However, it is closely associated with several autoimmune diseases including rheumatologic syndromes and has long been known to have several rheumatic manifestations particularly in association with hypothyroidism. More recently, it has also been implicated in rheumatologic syndromes in the absence of hypothyroidism or subclinical hypothyroidism. There is also an emerging body of evidence that ATD is highly linked to chronic generalized pain syndromes including fibromyalgia. This review examines the rheumatic symptoms of ATD described in the current literature and discusses the clinical relevance of ATD in general rheumatology. PMID:25618571

Tagoe, Clement E

2015-02-01

124

Eagle's syndrome: signs and symptoms.  

PubMed

Eagle's syndrome, an uncommon sequela of an elongated styloid process, can manifest itself as a sensation of a foreign body in the throat and a retrogoniac or anterolateral neck pain often referred to the TMJ and the ear. When treating patients affected by temporomandibular disorders (TMD), complaining of atypical orofacial pain, and with a concomitant radiographic finding of a bilaterally elongated styloid, the possible coexistence of Eagle's syndrome should always be considered. The aim of this review is to present an overview of the epidemiology, pathophysiology, diagnosis, and therapy for Eagle's syndrome and to help the clinician in differential diagnosis with other conditions that can provide similar signs and symptoms. PMID:23461263

Costantinides, Fulvia; Vidoni, Gabriele; Bodin, Christiane; Di Lenarda, Roberto

2013-01-01

125

Simulation of Traumatic Brain Injury Symptoms on the Personality Assessment Inventory: An Analogue Study.  

PubMed

The purpose of this study was to characterize the operating characteristics of the Personality Assessment Inventory (PAI) validity scales in distinguishing simulators feigning symptoms of traumatic brain injury (TBI) while completing the PAI (n = 84) from a clinical sample of patients with TBI who achieved adequate scores on performance validity tests (n = 112). The simulators were divided into two groups: (a) Specific Simulators feigning cognitive and somatic symptoms only or (b) Global Simulators feigning cognitive, somatic, and psychiatric symptoms. The PAI overreporting scales were indeed sensitive to the simulation of TBI symptoms in this analogue design. However, these scales were less sensitive to the feigning of somatic and cognitive TBI symptoms than the feigning of a broad range of cognitive, somatic, and emotional symptoms often associated with TBI. The relationships of TBI simulation to consistency and underreporting scales are also explored. PMID:24965838

Keiski, Michelle A; Shore, Douglas L; Hamilton, Joanna M; Malec, James F

2014-06-24

126

High-Yield Soluble Expression and Simple Purification of the Antimicrobial Peptide OG2 Using the Intein System in Escherichia coli  

PubMed Central

OG2 is a modified antimicrobial peptide, that is, derived from the frog peptide Palustrin-OG1. It has high antimicrobial activity and low cytotoxicity, and it is therefore promising as a therapeutic agent. Both prokaryotic (Escherichia coli) and eukaryotic (Pichia pastoris) production host systems were used to produce OG2 in our previous study; however, it was difficult to achieve high expression yields and efficient purification. In this study, we achieved high-yield OG2 expression using the intein fusion system. The optimized OG2 gene was cloned into the pTWIN1 vector to generate pTWIN-OG2-intein2 (C-terminal fusion vector) and pTWIN-intein1-OG2 (N-terminal fusion vector). Nearly 70% of the expressed OG2-intein2 was soluble after the IPTG concentration and induction temperature were decreased, whereas only 42% of the expressed of intein1-OG2 was soluble. Up to 75?mg of OG2-intein2 was obtained from a 1?l culture, and 85% of the protein was cleaved by 100?mM DTT. Intein1-OG2 was less amenable to cleavage due to the inhibition of cleavage by the N-terminal amino acid of OG2. The purified OG2 exhibited strong antimicrobial activity against E. coli K88. The intein system is the best currently available system for the cost-effective production of OG2. PMID:23936842

Xie, Yong-Gang; Han, Fei-Fei; Luan, Chao; Zhang, Hai-Wen; Feng, Jie; Choi, Young-Jun; Groleau, Denis; Wang, Yi-Zhen

2013-01-01

127

Depressive Symptoms Among Immigrant Latino Sexual Minorities  

PubMed Central

Objective To estimate the prevalence and identify correlates of depressive symptoms among immigrant Latino sexual minorities. Methods Respondent-driven sampling (RDS) was used to estimate the prevalence of depressive symptoms, and univariate and multivariable analyses were conducted to identify correlates of depressive symptoms. Results Unweighted and RDS-weighted prevalence estimates of depressive symptoms were 69.2% and 74.8%, respectively. In the multivariable analysis, low social support, sexual compulsivity, and high self-esteem were significantly associated with increased depressive symptoms. Conclusions A need exists for culturally congruent mental health services for immigrant Latino sexual minorities in the southern United States. PMID:23985187

Rhodes, Scott D.; Martinez, Omar; Song, Eun-Young; Daniel, Jason; Alonzo, Jorge; Eng, Eugenia; Duck, Stacy; Downs, Mario; Bloom, Fred R.; Allen, Alex Boeving; Miller, Cindy; Reboussin, Beth

2014-01-01

128

Solvarmeanlg fra Batec Solvarme A/S, Velux Danmark A/S og SONNENKRAFT Scandinavia  

E-print Network

Danmark A/S og Sonnenkraft Scandinavia A/S. Rapporten afslutter energiforskningsprojektet EFP07 blive videreført i 2009 i forskningsprojektet EFP07-II, Solvarmeanlægs energibesparelser, fase 2, hvor

129

Fri prosjektsttte: Nye prosjekter innenfor matematikk, naturvitenskap og teknologi (FRINATEK) fra 2014 Prosjekt Tittel Prosjektansvarlig  

E-print Network

-structure interaction in the upper airways Institutt for energi- og prosessteknikk, Norges Teknisk- Naturvitenskapelige (EME) Farmasøytisk institutt, Universitetet i Oslo 231741 Modeling of obstructive sleep apnea by fluid

Brandenburg, Axel

130

Self-Reported ADHD Symptoms among College Students: Item Positioning Affects Symptom Endorsement Rates  

ERIC Educational Resources Information Center

Objective: The effect of manipulating item positioning on self-reported ADHD symptoms was examined. We assessed whether listing DSM-IV ADHD symptoms serially or interspersed affected (a) the correlation between ADHD symptoms and (b) the rate of symptom endorsement. Method: In Study 1, an undergraduate sample (n = 102) completed a measure that…

Mitchell, John T.; Knouse, Laura E.; Nelson-Gray, Rosemery O.; Kwapil, Thomas R.

2009-01-01

131

Updated: 6/20/12 Symptom Management ServiceSymptom Management Service  

E-print Network

and counseling for both physical and emotional symptoms caused as a result of cancer. This includes treatment for pain, fatigue, depression, anxiety and spiritual distress. Treatments for these symptoms includeUpdated: 6/20/12 Symptom Management ServiceSymptom Management Service About the SMSAbout the SMS

Walter, Peter

132

Postural tachycardia syndrome is associated with significant symptoms and functional impairment predominantly affecting young women: a UK perspective  

PubMed Central

Objective To examine a large UK cohort of patients with postural tachycardia syndrome (PoTS), to compare demographic characteristics, symptoms and treatment of PoTS at one centre compared to the largest patient group PoTS UK and to verify if their functional limitation is similar to patients with chronic fatigue syndrome (CFS). Design A cross-sectional study assessed the frequency of symptoms and their associated variables. Patients and setting Two PoTS cohorts were: (1) recruited via PoTS UK, (2) diagnosed at Newcastle Hospitals National Health Service (NHS) Foundation Trust 2009–2012. Patients with PoTS were then compared to a matched cohort with CFS. Main outcome measures Patients’ detailed demographics, time to diagnosis, education, disability, medications, comorbidity and precipitants. Symptom assessment tools captured, Fatigue Impact Scale, Epworth Sleepiness Scale, Orthostatic Grading Scale (OGS), Hospital Anxiety and Depression Scale, Health Assessment Questionnaire, Cognitive Failures Questionnaire. Results 136 patients with PoTS participated (84 members of PoTS UK (170 cohort; 50% return) and 52 (87 cohort; 60%) from Newcastle Clinics). The PoTS UK population was significantly younger than the clinic patients, with significantly fewer men (p=0.005). Over 60% had a university or postgraduate degree. Significantly more of the PoTS UK cohort were working, with hours worked being significantly higher (p=0.001). Time to diagnosis was significantly longer in the PoTS UK cohort (p=0.04). Symptom severity was comparable between cohorts. The PoTS total group was compared with a matched CFS cohort; despite comparable levels of fatigue and sleepiness, autonomic symptom burden (OGS) was statistically significantly higher. The most common treatment regime included ?-blockers. Overall, 21 treatment combinations were described. Up to 1/3 were taking no treatment. Conclusions Patients with PoTS are predominantly women, young, well educated and have significant and debilitating symptoms that impact significantly on quality of life. Despite this, there is no consistent treatment. PMID:24934205

McDonald, Claire; Koshi, Sharon; Busner, Lorna; Kavi, Lesley; Newton, Julia L

2014-01-01

133

Stemmen uten ansikt : en virkemiddelanalyse av lydbåndet i Samuel Becketts Krapp's Last Tape og Tor Ulvens Gravgaver.  

E-print Network

??Denne oppgaven undersøker relasjonen mellom "autentisk" fortellerstemme og fortellerstemme mediert gjennom lydbånd i skuespillet "Krapp's Last Tape" av Samuel Beckett. Som komparativt eksempel analyseres båndopptaker-temaet… (more)

Oppedal, Torbjørn

2007-01-01

134

What Are the Signs and Symptoms of Heart Disease?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of Heart Disease? The signs and symptoms of coronary heart disease ( ... will have signs and symptoms of the disease. Heart Disease Signs and Symptoms The illustration shows the major ...

135

Rumination and negative symptoms in schizophrenia.  

PubMed

Rumination is thought to be an important maintaining factor in depression. Depressive symptomatology is also a prominent feature in schizophrenia. However, little is known about the relationship between rumination and symptoms, such as depression and negative symptoms, in schizophrenia. The present study examined associations between rumination and symptoms in a group of 37 stable medicated patients with schizophrenia. All participants were clinically assessed on their symptoms and completed self-reported measures of depression and rumination. The findings showed that negative symptoms, especially emotional withdrawal and stereotyped thinking, but not depressive symptomatology, were associated with rumination in the present sample of patients with schizophrenia. If the findings are replicated, interventions that reduce rumination and rigid thinking might be helpful to reduce some negative symptoms of psychosis. PMID:19752652

Halari, Rozmin; Premkumar, Preethi; Farquharson, Lorna; Fannon, Dominic; Kuipers, Elizabeth; Kumari, Veena

2009-09-01

136

Mastocytosis: mediator-related signs and symptoms.  

PubMed

Patients with systemic mastocytosis present symptoms related to the tissue response to the release of mediators from mast cells and to the local mast cell burden. Such patients often have a history of chronic and acute mediator-related symptoms. Most patients have indolent disease with a good prognosis and a normal life span. Symptoms can include pruritus, flushing, syncope, gastric distress, nausea and vomiting, diarrhea, bone pain and neuropsychiatric symptoms, most of which are controlled by medication. Because there is no current cure for mastocytosis, successful therapeutic interventions rely on the recognition of mediator-related symptoms and their treatment, and established intervention approaches for the relatively uncommon leukemic concomitants. Efforts to link a particular mast cell-derived mediator to some aspect of the symptom complex depend on the known actions of the mediator and the efficacy of target-based interventions. PMID:11919427

Castells, Mariana; Austen, K Frank

2002-02-01

137

Psychogenesis and somatogenesis of common symptoms.  

PubMed Central

There are situations in clinical practice in which the physican should keep in mind the influence of emotional factors in the elaboration of symptoms and yet should not conclude hastily that "all is in the patient's mind". Symptoms are often the result of complex etiologic factors including life-threatening illnesses presenting psychologic symptoms as an early manifestation. Psychologic disorders and physical illnesses with similar symptoms may coexist in the same patient. There are also cases in which the symptoms are the result of the constant interaction of psychologic and physical factors. Some suggestions to help to clarify the diagnosis are given and a classification of the different clinical situations involved is presented. Becuase physicians should be constantly aware of the complexity of the factors involved in the elaboration of obscure symptoms, some recommendations are given in regard to undergraduate and graduate medical education. PMID:1092455

Huapaya, L. V.

1975-01-01

138

Translating symptoms into mechanisms: functional GI disorders  

NSDL National Science Digital Library

Functional gastrointestinal disorders are the most common problem in gastroenterological practice. They are defined by chronic abdominal symptom complexes that occur in the absence of underlying structural abnormalities. The pathogenesis of these disorders is heterogeneous and involves behavioral, infective, and inflammatory components. Common symptoms are abdominal pain, diarrhea, constipation, and bloating. Mechanisms underlying these symptoms include alterations in gastrointestinal motility, visceral perception, altered epithelial function, and disturbances in fermentation activity by gut commensal bacteria.

2007-12-01

139

Autonomic nervous symptoms in primary Sjogren's; syndrome  

Microsoft Academic Search

Objectives. Objective signs of autonomic dysfunction (AD) have been reported in patients with primary SS (pSS) while the presence of associated symptoms has not been systematically studied. Therefore, the aims of this study were (i) to assess the presence and severity of various AD symptoms in pSS patients and (ii) to relate AD symptoms to other clinical features of pSS.

T. Mandl; V. Granberg; J. Apelqvist; P. Wollmer; R. Manthorpe; L. T. H. Jacobsson

2008-01-01

140

Symptom burden in individuals with cerebral palsy.  

PubMed

The current study sought to (1) determine the relative frequency and severity of eight symptoms in adults with cerebral palsy (CP), (2) examine the perceived course of these eight symptoms over time, and (3) determine the associations between the severity of these symptoms and psychosocial functioning. Eighty-three adults with CP completed a measure assessing the frequency, severity, and perceived course of eight symptoms (pain, weakness, fatigue, imbalance, numbness, memory loss, vision loss, and shortness of breath). Respondents also completed measures of community integration and psychological functioning. The results indicated that pain, fatigue, imbalance, and weakness were the most common and severe symptoms reported. All symptoms were reported to have either stayed the same or worsened, rather than resolved, over time. The symptoms were more closely related to social integration than to home integration, productive activity, or psychological functioning. Memory loss was a unique predictor of social integration in the multivariate context. This study highlighted several common and problematic symptoms experienced by adults with CP. Additional research is needed to identify the most effective treatments for those symptoms that affect community integration and psychological functioning as a way to improve the quality of life of individuals with CP. PMID:21174251

Hirsh, Adam T; Gallegos, Juan C; Gertz, Kevin J; Engel, Joyce M; Jensen, Mark P

2010-01-01

141

Autism and ADHD Symptoms in Patients with OCD: Are They Associated with Specific OC Symptom Dimensions or OC Symptom Severity?  

ERIC Educational Resources Information Center

In obsessive-compulsive disorder (OCD), the relationship between autism spectrum disorders (ASD), attention-deficit/hyperactivity disorder (ADHD) symptom, and obsessive-compulsive (OC) symptom dimensions and severity has scarcely been studied. Therefore, 109 adult outpatients with primary OCD were compared to 87 healthy controls on OC, ADHD and…

Anholt, Gideon E.; Cath, Danielle C.; van Oppen, Patricia; Eikelenboom, Merijn; Smit, Johannes H.; van Megen, Harold; van Balkom, Anton J. L. M.

2010-01-01

142

Dimensions of Temperament and Depressive Symptoms: Replicating a Three-Way Interaction  

PubMed Central

High negative emotionality (NE), low positive emotionality (PE), and low self-regulatory capacity (i.e., effortful control or EC) are related to depressive symptoms and furthermore, may moderate one another’s relations to such symptoms. Indeed, preliminary evidence suggests they may operate in a three-way interaction (Dinovo & Vasey, 2011), but the replicability of that finding remains unknown. Therefore, we tested this NExPExEC interaction in association with depressive symptoms in 5 independent samples. This interaction was significant in 4 of the 5 samples and a combined sample and approached significance in the fifth sample. In contrast, the NExPExEC interaction was unrelated to general anxious symptoms and thus may be specific to symptoms of depression. Implications, directions for future research, and limitations are discussed. PMID:24493906

Vasey, Michael W.; Harbaugh, Casaundra N.; Lonigan, Chistopher J.; Phillips, Beth M.; Hankin, Benjamin L.; Willem, Lore; Bijttebier, Patricia

2014-01-01

143

INFLUENZA 101 Symptoms of the flu  

E-print Network

INFLUENZA 101 Symptoms of the flu Sudden onset of fever/chills, coughing, muscle aches, headache by nausea and/or vomiting, minor symptoms e.g. fatigue may last a few weeks Self-care if you get the flu

Abolmaesumi, Purang

144

Somatic Symptoms in Traumatized Children and Adolescents  

ERIC Educational Resources Information Center

Childhood exposure to trauma has been associated with increased rates of somatic symptoms (SS), which may contribute to diminished daily functioning. One hundred and sixty-one children residing at a residential treatment home who had experienced neglect and/or abuse were administered the Trauma Symptom Checklist for Children (TSCC), the…

Kugler, Brittany B.; Bloom, Marlene; Kaercher, Lauren B.; Truax, Tatyana V.; Storch, Eric A.

2012-01-01

145

Accumulated childhood trauma and symptom complexity  

Microsoft Academic Search

The relationship between accumulated exposure to different types of traumatic events (cumulative trauma) in childhood and the total number of different types of symptomatology reported (symptom complexity) in adulthood was examined in a sample of 2,453 female university students. There was a linear relationship between the number of trauma types experienced by participants before 18 and symptom complexity. This effect

John Briere; Stacey Kaltman; Bonnie L. Green

2008-01-01

146

Depressive Symptoms in African-American Women.  

ERIC Educational Resources Information Center

Examined the prevalence of depressive symptoms in an African American female college student sample (n=78) using the Minnesota Multiphasic Personality Inventory (MMPI2) and the Beck Depression Inventory (BDI). MMPI-2 was a more conservative scale than BDI in identifying depressive symptom levels. Discusses stress inoculation methods to assist…

Reed, Michael K.; And Others

1996-01-01

147

Autism Symptom Topography and Maternal Socioemotional Functioning  

ERIC Educational Resources Information Center

Researchers examining the relationship of autism "symptomatology" and maternal stress have defined symptomatology in terms of level of severity, frequency of occurrence, or symptom type. In the present study, the relationship of maternal perceptions of these dimensions, along with a fourth, symptom diversity, and negative and positive indices of…

Ekas, Naomi; Whitman, Thomas L.

2010-01-01

148

Dreams as a cause of symptoms  

Microsoft Academic Search

Discusses the mechanism and interpretation of dreams. Dreams are examined as the causal factors of symptoms. They may be the source of depression in some individuals and these symptoms may persist. The manifest content of dreams is a distortion of a repressed wish of the dreamer. M. Prince (see Journal of Abnormal Psychology, Vol 5, 139-195, PA: 52638) has referred

G. A. Waterman

1910-01-01

149

Psychotic symptoms in Parkinson’s disease  

Microsoft Academic Search

Psychotic symptoms are common in Parkinson’s disease (PD) and occur in at least 20% of medication-treated patients. Benign visual hallucinations usually appear earlier, while malignant hallucinations, confusional states, delusions, paranoid beliefs, agitation, and delirium become more frequent with disease progression. Virtually all antiparkinsonian drugs may produce psychotic symptoms. Cognitive impairment, increased age, disease duration and severity, depression, and sleep disorders

Spiridon Papapetropoulos; D. C. Mash

2005-01-01

150

Common signs & symptoms of meningitis & septicaemia  

E-print Network

Common signs & symptoms of meningitis & septicaemia © Meningitis Trust July 2011 · Next review July at all. Early symptoms can include fever, headache, vomiting, muscle pain and fever with cold hands, cold hands & feet Unusual cry, moaning Tense, bulging fontanelle Neck stiffness, dislike bright lights

151

Neurological Symptoms in Achondroplastic Dwarfs - Surgical Treatment  

Microsoft Academic Search

Fourteen patients who had neurological symptoms associated with achondroplastic dwarfism and who had spine surgery were analyzed, as were an additional twenty-nine cases reported in the literature. Four types of neurological patterns emerged, based on the onset, symptoms, and physical examination. Some etiological correlation between the anatomical lesion and the result was made in each category, and a reli- able

LOWELL D. LUTTER

152

Behavioral and Psychological Symptoms in Alzheimer's Disease  

PubMed Central

Neuropsychiatric symptoms (NPS) such as depression, apathy, aggression, and psychosis are now recognized as core features of Alzheimer's disease (AD), and there is a general consensus that greater symptom severity is predictive of faster cognitive decline, loss of independence, and even shorter survival. Whether these symptoms result from the same pathogenic processes responsible for cognitive decline or have unique etiologies independent of AD-associated neurodegeneration is unclear. Many structural and metabolic features of the AD brain are associated with individual neuropsychiatric symptoms or symptom clusters. In addition, many genes have been identified and confirmed that are associated with symptom risk in a few cases. However, there are no single genes strongly predictive of individual neuropsychiatric syndromes, while functional and structural brain changes unique to specific symptoms may reflect variability in progression of the same pathological processes. Unfortunately, treatment success for these psychiatric symptoms may be lower when comorbid with AD, underscoring the importance of future research on their pathobiology and treatment. This review summarizes some of the most salient aspects of NPS pathogenesis. PMID:25133184

Li, Xiao-Ling; Tan, Meng-Shan

2014-01-01

153

Behavior and symptom identification scale 32  

Microsoft Academic Search

To be useful in assessing treatment efficacy, an outcome measure must be sensitive to changes in ratings of symptoms and psychosocial functioning over time and to differences in change across consumers and be interpretable as to the extent of clinical improvement. Results are presented regarding the sensitivity of the BASIS-32 to changes in ratings of symptoms and psychosocial functioning among

Jeanette M. Jerrell

2005-01-01

154

Cerebral emboli and depressive symptoms in dementia  

Microsoft Academic Search

BACKGROUND: The vascular depression hypothesis and our recent findings of increased frequency of spontaneous cerebral emboli in dementia suggest that such emboli may be involved in the causation of depressive symptoms in dementia. AIMS: To evaluate the association between spontaneous cerebral emboli and depressive symptoms in Alzheimer's disease and vascular dementia. METHOD: In a cohort of 142 patients with dementia

N. Purandare; R. C. Oude Voshaar; J. Hardicre; J. Byrne; C. N. McCollum; A. Burns

2006-01-01

155

What are the symptoms of flu? Symptoms include sudden onset of  

E-print Network

What are the symptoms of flu? · Symptoms include sudden onset of: o fever/chills o cough o muscle a doctor? Most people recover without needing to see a doctor; the flu usually lasts 7 ­ 10 days and goes · Disorientation or confusion · Pain or pressure in chest · Severe or persistent vomiting · Flu-like symptoms

Ellis, Randy

156

Associations between miscellaneous symptoms and symptom dimensions in adults with obsessive-compulsive disorder  

Microsoft Academic Search

Obsessive-compulsive disorder (OCD) is a debilitating psychiatric condition with a heterogeneous array of obsessions and compulsions. Although factor analytic studies have identified symptom dimensions comprising the clinical presentation of OCD, many frequently reported miscellaneous symptoms are not considered in factor analytic studies because they do not fit conceptually within a particular symptom category, despite being functionally related. In the present

Eric A. Storch; Joseph McNamara; Cary Jordan; Wendi E. Marien; Marni L. Jacob; Tanya K. Murphy; Wayne K. Goodman; Gary R. Geffken

2008-01-01

157

Spurious symptom reduction in fault monitoring  

NASA Technical Reports Server (NTRS)

Previous work accomplished on NASA's Faultfinder concept suggested that the concept was jeopardized by spurious symptoms generated in the monitoring phase. The purpose of the present research was to investigate methods of reducing the generation of spurious symptoms during in-flight engine monitoring. Two approaches for reducing spurious symptoms were investigated. A knowledge base of rules was constructed to filter known spurious symptoms and a neural net was developed to improve the expectation values used in the monitoring process. Both approaches were effective in reducing spurious symptoms individually. However, the best results were obtained using a hybrid system combining the neural net capability to improve expectation values with the rule-based logic filter.

Shontz, William D.; Records, Roger M.; Choi, Jai J.

1993-01-01

158

Managing dementia symptoms and needs using technology.  

PubMed

Dementia is a difficult and costly disease to manage. Although caregivers and patients have indicated they need support for activities of daily living and debilitating neuropsychological symptoms, most technology innovations focus on safety and social contact. This feasibility study tested a care technology designed to manage dementia symptoms and everyday routines using common, nonpharmacological interventions. It was implemented in two formal care environments (memory care, assisted living). In Sample 1, independent observers decided which symptoms were present or absent in individual residents pre-intervention and 1 and 2 months during the intervention. In Sample 2, independent observers determined the desired status (goals) for individual residents prior to intervention and evaluated resident status 1 and 2 months into the intervention. The intervention was associated with a reduction in symptoms and progression toward wellness goals, suggesting that nondrug interventions for managing symptoms and daily routines in dementia can be delivered effectively using advanced technology. PMID:24892310

Kerssens, Chantal; Sattler, Melany; Monteiro, Alisha

2014-07-01

159

Rungende malm og rbende roser.* En anmeldelse af Jakob Wolf (2004): Rosens Rb. Intelligent design i naturen.  

E-print Network

pseudovidenskabelige strømning, der kaldes "intelligent design theory". Teorien hævder, som William Paley og hele den. Intelligent design teorien er for mig at se kreationisme light, selvom dens tilhængere ikke direkte, som i den gennemgang af det sammensurium, der sammenfattes under overskriften intelligent design, og som udgøres af

Emmeche, Claus

160

Neighborhood Contexts, Fathers, and Mexican American Young Adolescents’ Internalizing Symptoms  

PubMed Central

The family stress model posits that contextual stressors, such as neighborhood danger, negatively influence youth adjustment, including internalizing symptoms, via disruptions in parenting and family processes. The current study examined a culturally and contextually modified family stress model in a diverse sample of Mexican origin fathers and their children (N = 463) from the Southwestern U.S. Results supported the hypothesized negative influence of neighborhood danger on youth internalizing symptoms via disruptions in family cohesion. Paternal warmth did not play a role in linking contextual stress to outcomes. The role of harsh parenting was highly nuanced. Results suggest that both culture and context have the potential to moderate putative family stress model associations for specific parenting behaviors and further our understanding of the ways that culture and context may operate in models of family stress and youth outcomes. PMID:22383856

White, Rebecca M. B.; Roosa, Mark W.

2011-01-01

161

Association of ventilation system type with SBS symptoms in office workers  

SciTech Connect

This paper provides a review and synthesis of current knowledge about the associations of ventilation system types in office buildings with sick building syndrome symptoms and discusses potential explanations for the associations. Relative to natural ventilation, air conditioning, with or without humidification, was consistently associated with a statistically significant increase in the prevalence of one or more SBS symptoms. Prevalences were typically higher by approximately 30% to 200% in the air conditioned buildings. In two of three assessments from a single study, symptom prevalences were also significantly higher in air conditioned buildings than in buildings with simple mechanical ventilation and no humidification. In approximately half of assessments, SBS symptom prevalences were significantly higher in buildings with simple mechanical ventilation than in buildings with natural ventilation. Insufficient information was available for conclusions about the potential increased risk of SBS symptoms with humidification. The statistically significant associations of mechanical ventilation and air conditioning with SBS symptoms are much more frequent than expected from chance and also not likely to be a consequence of confounding by several potential personal, job, or building related confounders. The reasons for the increases in symptom prevalences with mechanical ventilation and particularly with air conditioning remain unclear. Multiple deficiencies in HVAC system design, construction, operation, or maintenance, including some which cause pollutant emissions from HVAC systems, may contribute to the increases in symptom prevalences.

Seppanen, Olli; Fisk, William J.

2001-02-07

162

Impact of a joint labor-management ergonomics program on upper extremity musculoskeletal symptoms among garment workers  

Microsoft Academic Search

This study evaluated the effect of an ergonomics intervention program on the prevalence and intensity of symptoms of upper extremity work-related musculoskeletal disorders among 36 garment workers performing an operation called spooling. Adjustable chairs were introduced and workers were trained in their use. Symptom surveys were administered prior to and 6 months after introduction of adjustable chairs. Quantitative pre- and

Robin Herbert; Jonathan Dropkin; Nick Warren; Darius Sivin; John Doucette; Laurie Kellogg; Judith Bardin; Dan Kass; Steve Zoloth

2001-01-01

163

Sensory symptoms in autism spectrum disorders.  

PubMed

The aim of this review is to summarize the recent literature regarding abnormalities in sensory functioning in individuals with autism spectrum disorder (ASD), including evidence regarding the neurobiological basis of these symptoms, their clinical correlates, and their treatment. Abnormalities in responses to sensory stimuli are highly prevalent in individuals with ASD. The underlying neurobiology of these symptoms is unclear, but several theories have been proposed linking possible etiologies of sensory dysfunction with known abnormalities in brain structure and function that are associated with ASD. In addition to the distress that sensory symptoms can cause patients and caregivers, these phenomena have been correlated with several other problematic symptoms and behaviors associated with ASD, including restrictive and repetitive behavior, self-injurious behavior, anxiety, inattention, and gastrointestinal complaints. It is unclear whether these correlations are causative in nature or whether they are due to shared underlying pathophysiology. The best-known treatments for sensory symptoms in ASD involve a program of occupational therapy that is specifically tailored to the needs of the individual and that may include sensory integration therapy, a sensory diet, and environmental modifications. While some empirical evidence supports these treatments, more research is needed to evaluate their efficacy, and other means of alleviating these symptoms, including possible psychopharmacological interventions, need to be explored. Additional research into the sensory symptoms associated with ASD has the potential to shed more light on the nature and pathophysiology of these disorders and to open new avenues of effective treatments. PMID:24614766

Hazen, Eric P; Stornelli, Jennifer L; O'Rourke, Julia A; Koesterer, Karmen; McDougle, Christopher J

2014-01-01

164

Symptoms and Signs Associated with Postpartum Thyroiditis  

PubMed Central

Background. Postpartum thyroiditis (PPT) is a common triphasic autoimmune disease in women with thyroid peroxidase (TPO) autoantibodies. This study evaluated women's thyroid disease symptoms, physical findings, stress levels, and thyroid stimulating hormone (TSH) levels across six postpartum months in three groups, TPO negative, TPO positive, and PPT positive women. Methods. Women were recruited in midpregnancy (n = 631) and TPO status was determined which then was used to form the three postpartum groups. The three groups were compared on TSH levels, thyroid symptoms, weight, blood pressure, heart rate, a thyroid exam, and stress scores. Results. Fifty-six percent of the TPO positive women developed PPT. Hypothyroid group (F (2, 742) = 5.8, P = .003) and hyperthyroid group (F (2, 747) = 6.6, P = .001) subscale scores differed by group. Several symptoms and stress scores were highest in the PPT group. Conclusions. The normal postpartum is associated with many symptoms that mimic thyroid disease symptoms, but severity is greater in women with either TPO or PPT positivity. While the most severe symptoms were generally seen in PPT positive women, even TPO positive women seem to have higher risk for these signs and symptoms. PMID:25405057

2014-01-01

165

Comorbidity in operable lung cancer  

Microsoft Academic Search

Study objectives: To ascertain the frequency of diseases associated (comorbidity) with operable lung cancer (LC) globally, in relation to the presence of neoplastic clinical symptoms and age. Design: Prospective; multiinstitutional of 19 Spanish hospitals. Patients: Two thousand nine hundred and ninety two consecutive cases of LC, treated surgically by the Bronchogenic Carcinoma Co-operative Group of the Spanish Society of Pneumology

Angel López-Encuentra

2002-01-01

166

Neurotology symptoms at referral to vestibular evaluation  

PubMed Central

Background Dizziness-vertigo is common in adults, but clinical providers may rarely diagnose vestibular impairment and referral could be delayed. To assess neurotology symptoms (including triggers) reported by patients with peripheral vestibular disease, during the year just before their referral to vestibular evaluation. Methods 282 patients with peripheral vestibular disease and 282 control subjects accepted to participate. They had no middle ear, retinal, neurological, psychiatric, autoimmune or autonomic disorders. They reported their symptoms by a standardized questionnaire along with their anxiety/depression symptoms. Results Patients were referred after months or years from the onset of their symptoms, 24% of them reported frequent falls with a long clinical evolution; 10% of them reported no vertigo but instability related to specific triggers; 86% patients and 12% control subjects reported instability when moving the head rapidly and 79% patients and 6% control subjects reported instability when changing posture. Seven out of the 9 symptoms explored by the questionnaire allowed the correct classification of circa 95% of the participants (Discriminant function analysis, p?symptoms showed a mild correlation with the total score of symptoms (multiple R2 =0.18, p?symptoms may have a mild influence on the report of symptoms of vestibular disease in both, patients and control subjects. PMID:24279682

2013-01-01

167

Menopausal Symptoms and Complementary Health Practices  

MedlinePLUS

... findings from this research are highlighted below. Top Botanicals Black cohosh ( Actaea racemosa, Cimicifuga racemosa ). This herb ... possible effects on menopausal symptoms than have other botanicals. Studies of its effectiveness in reducing hot flashes ...

168

Symptoms and Complications of Flu (Influenza)  

MedlinePLUS

... JavaScript on. Read more information on enabling JavaScript. Flu (Influenza) Skip Content Marketing Share this: Main Content ... Open All Influenza Symptoms People who have the flu often experience Fever Feeling feverish/chills Cough Sore ...

169

Modified Protein Improves Vitiligo Symptoms in Mice  

MedlinePLUS

... August 2013 Modified Protein Improves Vitiligo Symptoms in Mice Altering a key protein involved in the development ... pigmentation loss associated with the skin disorder in mice, according to recent research funded by the NIH’s ...

170

Symptoms of Post-traumatic Stress Disorder  

E-print Network

. Sexual trauma was found to have an extremely negative impact on PTSD symptoms, negative attachment style, and increased substance use. Women experienced more sexual traumas, while men reported more violent, non-sexual traumas. Implications...

Hall, Christy Ann

2013-02-22

171

Home Care Nursing Improves Cancer Symptom Management  

Cancer.gov

Home care nursing (HCN) improves the management of symptoms in breast and colorectal cancer patients who take the oral chemotherapy drug capecitabine, according to a study published online November 16, 2009, in the Journal of Clinical Oncology.

172

HIV / AIDS: Symptoms, Diagnosis, Prevention and Treatment  

MedlinePLUS

... Navigation Bar Home Current Issue Past Issues HIV / AIDS HIV / AIDS: Symptoms , Diagnosis, Prevention and Treatment Past Issues / Summer ... and have resulted in a dramatic decrease in AIDS deaths in the U.S. NIH Research to Results ...

173

What Are the Symptoms of Uterine Fibroids?  

MedlinePLUS

... it? How is it diagnosed? What are the treatments for it? Other FAQs NICHD Research Information Clinical Trials Resources and Publications En Español What are the symptoms of uterine fibroids? Skip sharing on social media links Share this: ...

174

Symptoms of FSHD (Facioscapulohumeral Muscular Dystrophy)  

MedlinePLUS

... Make a Recurring Gift Planned Giving Gifts of Stock Matching Gifts Workplace Giving Attend FSH Society Events ... may be mistakenly attributed to strain or a sports injury. Symptoms may manifest early, sometimes years before ...

175

Feature Hepatitis: Hepatitis Symptoms, Diagnosis, Treatment & Prevention  

MedlinePLUS

... Navigation Bar Home Current Issue Past Issues Feature Hepatitis Hepatitis: Symptoms, Diagnosis, Treatment & Prevention Past Issues / Spring 2009 ... No appetite Fever Headaches Diagnosis To check for hepatitis viruses, your doctor will test your blood. You ...

176

Measuring Symptoms in Community-dwelling Older Adults: The Psychometric Properties of a Brief Symptom Screen  

PubMed Central

Background With aging, the probability of experiencing multiple chronic conditions is increased, along with symptoms associated with these conditions. Symptoms form a central component of illness burden and distress. To date, most symptom measures have focused on a particular disease population. Objective We sought to develop and evaluate a simple symptom screen using data obtained from a representative sample of community-dwelling older adults. Methods Psychometric analyses were conducted on 10 self-reported dichotomous symptom indicators collected during in-person interviews from a sample of 1000 community-dwelling older adults. Symptoms included shortness of breath, feeling tired or fatigued, problems with balance or dizziness, perceived weakness in legs, constipation, daily pain, stiffness, poor appetite, anxiety, and anhedonia. Results Over one-third of the sample (37.4%) had 5 or more concurrent symptoms. Stiffness and feeling tired were the most common symptoms. Confirmatory factor analyses were performed on the 10 symptoms for single factor and bifactor (physical and affective) models of symptom reporting. Goodness of fit indices indicated better fit for the bifactor model (?2df=10=89.6, p<0.001) but the practical significance of the improvement in fit was negligible. Differential item functioning (DIF) analyses showed some differences of relatively high magnitude in location parameters by race; however, because the DIF was in different directions, the impact on the overall measure was most likely lessened. Conclusion Among community-dwelling older adults, a large proportion experienced multiple co-occurring symptoms. This Brief Symptom Screen can be used to quickly measure overall symptom load in older adult populations, including those with multiple chronic conditions. PMID:23969593

Ritchie, Christine S; Hearld, Kristine R; Gross, Alden; Allman, Richard; Sawyer, Patricia; Sheppard, Kendra; Salanitro, Amanda; Locher, Julie; Brown, Cynthia J.; Roth, David L.

2014-01-01

177

Respiratory symptoms and diseases among construction painters  

Microsoft Academic Search

Objective: To study the self-reported prevalence of respiratory symptoms and diseases among construction painters and estimate the potential risk for this group compared with a representative group of carpenters sharing the construction work environment but without significant exposure to paint. Methods: A questionnaire study was conducted on 1,000 male Finnish construction painters and 1,000 carpenters (mean response rate 60.5%). Symptoms

Ari Kaukiainen; Riitta Riala; Rami Martikainen; Kari Reijula; Hilkka Riihimäki; Lauri Tammilehto

2005-01-01

178

Delayed Bedtimes and Obsessive Compulsive Symptoms  

Microsoft Academic Search

There is increasing recognition of an important interplay between psychiatric disorders and sleep. Clinical observations and several empirical studies have shown that later bedtimes are associated with obsessive-compulsive disorder (OCD). The current study examined the relationship of delayed bedtimes and symptoms of OCD. Two-hundred and sixty-six undergraduates completed a battery of questionnaires assessing sleep patterns, mood, and OC symptoms. Results

Meredith E. Coles; Jessica R. Schubert; Katherine M. Sharkey

2012-01-01

179

Functional (psychogenic) symptoms in Parkinson's disease.  

PubMed

It has been reported that patients who have Parkinson's disease have a high prevalence of somatisation (functional neurological symptoms) compared with patients who have other neurodegenerative conditions. Numerous explanations have been advanced for this phenomenon. Here, with illustrative cases, we discuss this topic, including its clinical importance, and suggest a link between the pathophysiology of Parkinson's disease and the proposed propensity to develop functional symptoms. PMID:23737007

Pareés, Isabel; Saifee, Tabish A; Kojovic, Maja; Kassavetis, Panagiotis; Rubio-Agusti, Ignacio; Sadnicka, Anna; Bhatia, Kailash P; Edwards, Mark J

2013-10-01

180

Tackling Negative Symptoms of Schizophrenia with Memantine  

PubMed Central

We present a case of a 52-year-old male patient suffering from chronic schizophrenia stabilized on risperidone long-acting injection (37,5?mg/2 weeks) and biperiden 4?mg/day. Residual symptoms are affective flattening, alogia, avolition, and asociality. Memantine 10?mg/day was added. After 1.5 months, the patient spontaneously referred to “feel better being in company of my relatives.” The following scales have been completed: the Scale for the Assessment of Negative Symptoms (96), the Scale for the Assessment of Positive Symptoms (3), the Mini Mental Scale Examination (26), and the Calgary Depression for Schizophrenia Scale (2). Memantine was increased to 20?mg/day and biperiden was decreased to 2?mg/day. Two months later, apathy and asociality considerably improved and affective flattening, alogia, and attention slightly got better (SANS 76, SAPS 1, MMSE 26, and CDSS 1). After two more months, the improvement continued in the same domains (SANS: 70, SAPS: 1 MMSE: 27, and CDSS: 1). Positive symptoms remained in full remission. It has been hypothesized that one of the causes of schizophrenia is glutamate excitotoxicity. Memantine, a glutamate receptor antagonist, could possibly ameliorate schizophrenia symptoms, the negative ones among them, used as add-on therapy to atypical antipsychotics. Memantine could be of potential help in schizophrenia patients with severe residual negative symptoms. PMID:24818033

2014-01-01

181

Thymolipoma combined with hyperthyroidism discovered by neurological symptoms.  

PubMed

Thymolipomas are rare slow-growing mediastinal thymic neoplasms. Most cases are asymptomatic and are sometimes discovered as a huge mass on chest x-ray films. A few cases have been discovered during examinations for other diseases. We report the second case of thymolipoma combined with hyperthyroidism in the English language literature. Neurological symptoms suddenly appeared in a 45-year-old woman. Central nervous system disorder was suggested but no significant abnormalities were found on brain MR nor were there any neurological signs. Several months later, neurological and systemic examinations on admission revealed hyperthyroidism and an anterior mediastinal tumor, 9.0x5.0x3.0 cm in size on chest CT films. Despite treatment of hyperthyroidism by medication, her neurological symptoms remained. Neurologists recommended resection of the mediastinal tumor. Malignancy could not be ruled out because of the irregularity of the tumor appearance on contrast-enhanced chest CT. Furthermore, the tumor appeared to be attached to the ascending aorta, so cytological and/or pathological diagnosis by CT-guided needle biopsy before operation were contraindicated. Extended thymectomy was performed in May 2005. The pathological diagnosis was benign thymolipoma consisting of mature fatty tissue and thymic tissue structures with Hassall's corpuscles. Her neurological symptoms seemed slightly but not markedly improved. The relationship between thymolipoma and hyperthyroidism is still unknown. PMID:17505419

Takahashi, Hidenobu; Harada, Masahiko; Kimura, Masakazu; Kato, Harubumi

2007-04-01

182

20 CFR 220.114 - Evaluation of symptoms, including pain.  

Code of Federal Regulations, 2013 CFR

...true Evaluation of symptoms, including pain. 220.114 Section 220.114 Employees...114 Evaluation of symptoms, including pain. (a) General. In determining...of the claimant's symptoms, including pain, and the extent to which...

2013-04-01

183

20 CFR 220.114 - Evaluation of symptoms, including pain.  

Code of Federal Regulations, 2012 CFR

...false Evaluation of symptoms, including pain. 220.114 Section 220.114 Employees...114 Evaluation of symptoms, including pain. (a) General. In determining...of the claimant's symptoms, including pain, and the extent to which...

2012-04-01

184

20 CFR 220.114 - Evaluation of symptoms, including pain.  

Code of Federal Regulations, 2011 CFR

...false Evaluation of symptoms, including pain. 220.114 Section 220.114 Employees...114 Evaluation of symptoms, including pain. (a) General. In determining...of the claimant's symptoms, including pain, and the extent to which...

2011-04-01

185

20 CFR 220.114 - Evaluation of symptoms, including pain.  

Code of Federal Regulations, 2014 CFR

...true Evaluation of symptoms, including pain. 220.114 Section 220.114 Employees...114 Evaluation of symptoms, including pain. (a) General. In determining...of the claimant's symptoms, including pain, and the extent to which...

2014-04-01

186

What Are the Signs and Symptoms of Anemia?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of Anemia? The most common symptom of anemia is fatigue ( ... mild symptoms or none at all. Complications of Anemia Some people who have anemia may have arrhythmias ( ...

187

What Are the Signs and Symptoms of Fanconi Anemia?  

MedlinePLUS

... What Are the Signs and Symptoms of Fanconi Anemia? Major Signs and Symptoms Your doctor may suspect ... sisters also should be tested for the disorder. Anemia The most common symptom of all types of ...

188

Feature: Post Traumatic Stres Disorder PTSD: Symptoms, Diagnosis, Treatment  

MedlinePLUS

... Navigation Bar Home Current Issue Past Issues Feature PTSD Symptoms, Diagnosis , Treatment Past Issues / Winter 2009 Table ... Symptoms As with mild traumatic brain injury (TBI), PTSD symptoms can be very subtle. "For example, some ...

189

What Are the Signs and Symptoms of Carotid Artery Disease?  

MedlinePLUS

... What Are the Signs and Symptoms of Carotid Artery Disease? Carotid artery disease may not cause signs or symptoms until it severely narrows or blocks a carotid artery. Signs and symptoms may include a bruit (broo- ...

190

What Are the Signs and Symptoms of Sarcoidosis?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of Sarcoidosis? Many people who have sarcoidosis have no signs ... symptom is more common in women than men. Sarcoidosis Signs and Symptoms The illustration shows the major ...

191

What Are the Signs and Symptoms of Heart Failure?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of Heart Failure? The most common signs and symptoms of heart ... in your lungs. The condition requires emergency treatment. Heart Failure Signs and Symptoms The image shows the major ...

192

What Are the Signs and Symptoms of Asthma?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of Asthma? Common signs and symptoms of asthma include: Coughing . ... during the day or at night. What Causes Asthma Symptoms To Occur? Many things can trigger or ...

193

Web-Based Intervention for Returning Veterans with Symptoms of Posttraumatic Stress Disorder and Risky Alcohol Use  

Microsoft Academic Search

A substantial number of military personnel who have served in Iraq (Operation Iraqi Freedom; OIF) and Afghanistan (Operating\\u000a Enduring Freedom; OEF) develop symptoms of posttraumatic stress disorder (PTSD) in response to their military experiences\\u000a and many of these same individuals will drink in a risky or problematic manner following deployment. If left untreated, PTSD\\u000a symptoms and alcohol problems can become

Amy Rubin; Justin L. Enggasser; Monica Roy; Terence M. Keane

194

A randomized controlled trial of an HIV/AIDS Symptom Management Manual for depressive symptoms.  

PubMed

Abstract Depressive symptoms are highly prevalent, underdiagnosed, and undertreated in people living with HIV/AIDS (PLWH), and are associated with poorer health outcomes. This randomized controlled trial examined the effects of the HIV/AIDS Symptom Management Manual self-care symptom management strategies compared with a nutrition manual on depressive symptoms in an international sample of PLWH. The sample consisted of a sub-group (N=222) of participants in a larger study symptom management study who reported depressive symptoms. Depressive symptoms of the intervention (n=124) and control (n=98) groups were compared over three months: baseline, one-month, and two-months. Use and effectiveness of specific strategies were examined. Depressive symptom frequency at baseline varied significantly by country (? (2) 12.9; p=0.04). Within the intervention group there were significant differences across time in depressive symptom frequency [F(2, 207) = 3.27, p=0.05], intensity [F(2, 91) = 4.6, p=0.01], and impact [F(2, 252) = 2.92, p= 0.05), and these were significantly lower at one month but not at two months, suggesting that self-care strategies are effective in reducing depressive symptoms, however effects may be short term. Most used and most effective self-care strategies were distraction techniques and prayer. This study suggests that people living with HIV can be taught and will employ self-care strategies for management of depressive symptoms and that these strategies are effective in reducing these symptoms. Self-care strategies are noninvasive, have no side-effects, and can be readily taught as an adjunct to other forms of treatment. Studies are needed to identify the most effective self-care strategies and quantify optimum dose and frequency of use as a basis for evidence-based practice. PMID:22880943

Eller, Lucille S; Kirksey, Kenn M; Nicholas, Patrice K; Corless, Inge B; Holzemer, William L; Wantland, Dean J; Willard, Suzanne S; Robinson, Linda; Hamilton, Mary Jane; Sefcik, Elizabeth F; Moezzi, Shahnaz; Mendez, Marta Rivero; Rosa, Maria; Human, Sarie

2013-01-01

195

Patients' descriptions of angina symptoms: a qualitative study of primary care patients  

PubMed Central

Background Initial diagnosis of angina in primary care is based on the history of symptoms as described by the patient in consultation with their GP. Deciphering and categorising often complex symptom narratives, therefore, represents an ongoing challenge in the early diagnosis of angina in primary care. Aim To explore how patients with a preexisting angina diagnosis describe their symptoms. Method Semi-structured interviews were conducted with 64 males and females, identified from general practice records as having received a diagnosis of angina within the previous 5 years. Results While some patients described their angina symptoms in narratives consistent with typical anginal symptoms, others offered more complex descriptions of their angina experiences, which were less easy to classify. The latter was particularly the case for severe coronary artery disease, where some patients tended to downplay chest pain or attribute their experience to other causes. Conclusion Patients with a known diagnosis of angina do not always describe their symptoms in a way that is consistent with Diamond and Forrester’s diagnostic framework for typicality of angina. Early diagnosis of angina in primary care requires that GPs operate with a broad level of awareness of the various ways in which their patients describe their symptoms. PMID:20883622

Jones, Melvyn M; Somerville, Claire; Feder, Gene; Foster, Gill

2010-01-01

196

Reviewing the Dissociative Symptoms in Patients With Schizophreniaand their Association With Positive and Negative Symptoms  

PubMed Central

Objective: The present study aimed to clarify dissociative symptoms in patients with schizophrenia and its association with negative and positive symptom of schizophrenia. Methods: Based on the 4th edition of Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria, 80 schizophrenic subjects were randomly selected from patients who referred to the clinics of psychiatry hospital in Kerman, Iran. Eighty non-schizophrenic patients were chosen as the control group. Both groups were evaluated for dissociation symptom using the Dissociative Experience Scale (DES). Positive and Negative Syndrome Scale (PANSS) score was also used in the case group for determination of positive and negative symptom of schizophrenia. Results: The prevalence of dissociation symptom was 13% and 4% among schizophrenic and control groups, respectively (p = 0.02). In addition, there was a statistical significant association between DES score and positive symptom in schizophrenia (p = 0.02). Conclusion: The association between dissociative symptom and schizophrenia was significant and dissociative symptoms were associated with positive symptoms of schizophrenia. Declaration of interest: None. PMID:24995025

Ghoreishi, Abolfazl; Shajari, Zahra

2014-01-01

197

OG.4.3.34 1 Atmospheric Cherenkov Detectors at Milagro to Measure  

E-print Network

OG.4.3.34 1 Atmospheric Cherenkov Detectors at Milagro to Measure Cosmic­Ray Composition Above 50 Angle Cherenkov Telescope (WACT) experiment is currently being constructed at the Fenton Hill Observatory, located near Los Alamos, New Mexico. WACT consists of six air Cherenkov telescopes, each with 3

California at Santa Cruz, University of

198

Priv.-Doz. Dr. Thomas DreibholzForsker og utvikler av datanettverk Personlige opplysninger  

E-print Network

://www.iem.uni-due.de/dreibh/rserpool/ Oktober 2002 Sertifisering som Cisco Certified Network Associate (CCNA) og Cisco Cer- tified Academy Instructor (CCAI) fra Cisco Networking Academy ved Uni- versitetet i Duisburg-Essen i Essen, Tyskland Traffic Control, nettverkssikkerhet 2002 ­ 2012 Cisco Certified Academy Instructor (CCAI) i Cisco

Dreibholz, Thomas

199

From Black Power to Hip-Hop: Jeffrey O.G. Ogbar  

ERIC Educational Resources Information Center

While history for most conjures up images of places and experiences far removed, for Dr. Jeffrey O.G. Ogbar, the field provides a "wonderful medium" to illuminate contemporary issues as well. Much of Ogbar's current research centers on events occurring in the latter half of the 20th century, such as the civil rights and Black power movements as…

Smiles, Robin V.

2005-01-01

200

Chap t e r 2. Techno l og i e s 2.1. Full Custom  

E-print Network

Chap t e r 2. Techno l og i e s 2.1. Full Custom A full custom integrated circuit (IC to a foundry to be fabricated. In general, an IC is created by imprinting a circuit into a wafer of silicon) is constructed entirely by its designer [13][18]. Each transistor, connection, and wire is laid out by hand

Hauck, Scott

201

Symptom onset in autosomal dominant Alzheimer disease  

PubMed Central

Objective: To identify factors influencing age at symptom onset and disease course in autosomal dominant Alzheimer disease (ADAD), and develop evidence-based criteria for predicting symptom onset in ADAD. Methods: We have collected individual-level data on ages at symptom onset and death from 387 ADAD pedigrees, compiled from 137 peer-reviewed publications, the Dominantly Inherited Alzheimer Network (DIAN) database, and 2 large kindreds of Colombian (PSEN1 E280A) and Volga German (PSEN2 N141I) ancestry. Our combined dataset includes 3,275 individuals, of whom 1,307 were affected by ADAD with known age at symptom onset. We assessed the relative contributions of several factors in influencing age at onset, including parental age at onset, age at onset by mutation type and family, and APOE genotype and sex. We additionally performed survival analysis using data on symptom onset collected from 183 ADAD mutation carriers followed longitudinally in the DIAN Study. Results: We report summary statistics on age at onset and disease course for 174 ADAD mutations, and discover strong and highly significant (p < 10?16, r2 > 0.38) correlations between individual age at symptom onset and predicted values based on parental age at onset and mean ages at onset by mutation type and family, which persist after controlling for APOE genotype and sex. Conclusions: Significant proportions of the observed variance in age at symptom onset in ADAD can be explained by family history and mutation type, providing empirical support for use of these data to estimate onset in clinical research. PMID:24928124

Acosta-Baena, Natalia; Aisen, Paul S.; Bird, Thomas; Danek, Adrian; Fox, Nick C.; Goate, Alison; Frommelt, Peter; Ghetti, Bernardino; Langbaum, Jessica B.S.; Lopera, Francisco; Martins, Ralph; Masters, Colin L.; Mayeux, Richard P.; McDade, Eric; Moreno, Sonia; Reiman, Eric M.; Ringman, John M.; Salloway, Steve; Schofield, Peter R.; Sperling, Reisa; Tariot, Pierre N.; Xiong, Chengjie; Morris, John C.; Bateman, Randall J.

2014-01-01

202

Killing in combat, mental health symptoms, and suicidal ideation in Iraq war veterans.  

PubMed

This study examined combat and mental health as risk factors of suicidal ideation among 2854 U.S. soldiers returning from deployment in support of Operation Iraqi Freedom. Data were collected as part of a postdeployment screening program at a large Army medical facility. Overall, 2.8% of soldiers reported suicidal ideation. Postdeployment depression symptoms were associated with suicidal thoughts, while postdeployment PTSD symptoms were associated with current desire for self harm. Postdeployment depression and PTSD symptoms mediated the association between killing in combat and suicidal thinking, while postdeployment PTSD symptoms mediated the association between killing in combat and desire for self harm. These results provide preliminary evidence that suicidal thinking and the desire for self-harm are associated with different mental health predictors, and that the impact of killing on suicidal ideation may be important to consider in the evaluation and care of our newly returning veterans. PMID:21333486

Maguen, Shira; Luxton, David D; Skopp, Nancy A; Gahm, Gregory A; Reger, Mark A; Metzler, Thomas J; Marmar, Charles R

2011-05-01

203

Migraine-related symptoms in childhood.  

PubMed

Periodic disorders of childhood often represent precursors of migraine. As we advance our knowledge of migraine and its complicated phenotypic presentation in childhood, we have noted the similarities in overlapping symptoms of children presenting with childhood periodic syndromes. There is often a positive family history of migraine in children that present with periodic syndromes. There is a known transformation of periodic syndromes from childhood into adult migraine with and without aura phenotype. There has been an evolution of our understanding of what was initially referred to as periodic symptoms of childhood and more recently been called childhood periodic syndromes and is now evolving into the terminology of episodic symptoms that are associated with migraine. International classification of headache disorders has been instrumental in the evolution of the classification of headache and children adults. The most recent classification utilizes and replaces the periodic symptom terminology with episodic symptoms that will no longer be limited to just childhood. This article will address the evolution of our understanding of the diagnostic criteria, pathophysiology and management of the episodic syndromes that may be associated with migraine. PMID:23961555

Winner, Paul

2013-08-01

204

Natural History of Multiple Sclerosis Symptoms  

PubMed Central

The North American Research Committee on Multiple Sclerosis (NARCOMS) Registry is a database that contains information from over 35,000 patient volunteers on symptom severity in 11 domains commonly affected in multiple sclerosis (MS): mobility, hand function, vision, fatigue, cognition, bowel/bladder function, sensory, spasticity, pain, depression, and tremor/coordination. The Registry affords a unique opportunity to study the frequency and severity of domain-specific impairment in a contemporary, mostly treated MS cohort over the course of the disease. The objective of this work was to calculate symptom prevalence in each of the 11 domains for years 0 to 30 from symptom onset. The resulting “symptom prevalence tables” demonstrate that a majority of participants perceive at least some degree of impairment in most domains as early as the first year of disease. The severity of impairment increases with disease duration across all domains, but the patterns of disability accumulation differ. The symptom prevalence tables illustrate the magnitude of perceived impact of the disease and highlight the extent of unmet need in symptomatic management. The tables are easy to use and allow MS patients and their clinicians to compare an individual's own impairment in any of the 11 domains to that of NARCOMS participants with the same disease duration. PMID:24453777

Bacon, Tamar E.; Chamot, Eric; Salter, Amber R.; Cutter, Gary R.; Kalina, Jennifer T.; Herbert, Joseph

2013-01-01

205

Poor awareness of symptoms of oesophageal cancer.  

PubMed

Oesophageal cancer presents as advanced disease; in the majority of patients the symptoms are present for many months prior to diagnosis. Dysphagia has been described as the key to an early diagnosis of oesophageal cancer. This study aims to assess the public perception of the importance of this symptom. Ninety-six patients completed a questionnaire. This evaluated patient understanding of symptoms of dysphagia compared to the finding of a breast lump, haemoptysis, chest pain and loss of weight concerning urgency, probable cause of symptoms and treatment required. Sixty-five patients (71%) would visit their GP within 24 h of finding a breast lump or suffering from haemoptysis (82%) or having chest pain (82%). Forty-seven patients (51%) who experienced dysphagia would seek medical advice after one week and further 18 (19%) after one month (P<0.0001). Only eight patients (10%) associated dysphagia with cancer compared to 53 patients (57%) with the finding of a breast lump (P<0.031). This study concludes that there is poor understanding of the main symptoms of oesophageal cancer. New health campaigns are needed if the cancer is to be detected at an earlier and potentially curable stage. PMID:20926460

Tentzeris, Vasileios; Lake, Blossom; Cherian, Thomas; Milligan, James; Sigurdsson, Audun

2011-01-01

206

Psychotic and compulsive symptoms in Parkinson's disease.  

PubMed

The objective of this study is to evaluate psychiatric symptoms in Parkinson's disease (PD) patients and to assess their relation with other clinical aspects of PD. Psychotic symptoms (PS) and compulsive symptoms (CS) as well as other nonmotor and motor features were evaluated in 353 PD patients. Psychotic and compulsive symptom scores did not correlate significantly. PS occurred in 65% of patients, with item frequencies ranging from 10% (paranoid ideation) to 55% (altered dream phenomena). Regression analysis showed that autonomic impairment accounted for 20% of the 32% explained variance of PS, whereas cognitive problems, depression, daytime sleepiness, and dopamine agonist (DA) dose explained the rest. CS occurred in 19%, with item frequencies of 10% for both sexual preoccupation and compulsive shopping/gambling. Patients with more severe CS (score > or = 2 on one or both items) were significantly more often men, had a younger age at onset, a higher DA dose and experienced more motor fluctuations compared to the other patients. PS and CS are common but unrelated psychiatric symptoms in PD. The relations found between PS and cognitive problems, depression, daytime sleepiness, and autonomic impairment suggests a resemblance with Dementia with Lewy Bodies. The prominent association between PS and autonomic impairment may be explained by a shared underlying mechanism. Our results confirm previous reports on the profile of patients developing CS, and mechanisms underlying motor fluctuations may also play a role in the development of CS in PD. PMID:19133665

Verbaan, Dagmar; van Rooden, Stephanie M; Visser, Martine; Marinus, Johan; Emre, Murat; van Hilten, Jacobus J

2009-04-15

207

Depressive symptoms in institutionalized older adults  

PubMed Central

OBJECTIVE To estimate the prevalence of depressive symptoms among institutionalized elderly individuals and to analyze factors associated with this condition. METHODS This was a cross-sectional study involving 462 individuals aged 60 or older, residents in long stay institutions in four Brazilian municipalities. The dependent variable was assessed using the 15-item Geriatric Depression Scale. Poisson’s regression was used to evaluate associations with co-variables. We investigated which variables were most relevant in terms of presence of depressive symptoms within the studied context through factor analysis. RESULTS Prevalence of depressive symptoms was 48.7%. The variables associated with depressive symptoms were: regular/bad/very bad self-rated health; comorbidities; hospitalizations; and lack of friends in the institution. Five components accounted for 49.2% of total variance of the sample: functioning, social support, sensory deficiency, institutionalization and health conditions. In the factor analysis, functionality and social support were the components which explained a large part of observed variance. CONCLUSIONS A high prevalence of depressive symptoms, with significant variation in distribution, was observed. Such results emphasize the importance of health conditions and functioning for institutionalized older individuals developing depression. They also point to the importance of providing opportunities for interaction among institutionalized individuals. PMID:24897042

Santiago, Lívia Maria; Mattos, Inês Echenique

2014-01-01

208

Symptom Management in Metastatic Breast Cancer  

PubMed Central

Approximately 40,000 women die as a result of breast cancer each year and many more live with advanced disease. When breast cancer recurs, the goals of treatment often shift from one of cure to controlling the disease for as long as possible while palliating symptoms interfering with the patient's functional status and quality of life. This requires ongoing discussions with the patient and family about the goals of care. Many symptoms depend on the site of metastasis, with bone being the most frequent, and commonly occur with fatigue, depression, insomnia, and pain. The purpose of this paper is to identify and provide an overview of the management of the most common symptoms in patients with breast cancer metastases. PMID:21880861

Irvin, William; Muss, Hyman B.

2011-01-01

209

Influence of aeroionotherapy on some psychiatric symptoms  

NASA Astrophysics Data System (ADS)

Negative aeroionotherapy (daily 15 50 min sittings, for 10 30 days) was applied in 112 patients with various psychiatric disorders, especially neuroses, with the aim of ameliorating certain symptoms (target symptoms). Corona and water air ion generators, as well as electro-aerosol generators, were used. The aeroionization (small air ion concentration), at the patient's respiration level, was moderate: n-=10,000 15,000/ml air; n+s?1,000/ml air; q=n+/n-?0.1. In most treated patients a diminution or even the disappearance of the target symptoms was obtained. Those obviously ameliorated under the influence of aeroionotherapy were: asthenia, depressive reactions, anxiety, irascibility, cephalea, insomnia, and general indisposition.

Deleanu, M.; Stamatiu, C.

1985-03-01

210

Stress, depression, and anxiety predict average symptom severity and daily symptom fluctuation in systemic lupus erythematosus  

Microsoft Academic Search

Forty-one subjects diagnosed with systemic lupus erythematosus (SLE) were recruited from across the United States. Regressions were conducted to evaluate the relation among stress, depression, anxiety, anger, and SLE symptom complaints. Negative weighting of major life events predicted symptom history. Significant hierarchical regressions using negative weighting of major life events, impact of daily stress, depression, anxiety, and anger were found

Serrhel G. Adams; Paul M. Dammers; Tara L. Saia; Phillip J. Brantley; Gerard R. Gaydos

1994-01-01

211

Dynamic Associations between Maternal Depressive Symptoms and Adolescents' Depressive and Externalizing Symptoms  

ERIC Educational Resources Information Center

The current prospective study investigated transactional relations between maternal depressive symptoms and children's depressive and externalizing symptoms. Participants included 240 children (M age = 11.86 years, SD = 0.56; 53.9% female) and their mothers who were part of a 6-year longitudinal study. Measures of maternal depression (Beck…

Kouros, Chrystyna D.; Garber, Judy

2010-01-01

212

Do Symptoms of Sluggish Cognitive Tempo in Children with ADHD Symptoms Represent Comorbid Internalizing Difficulties?  

ERIC Educational Resources Information Center

Objective: Symptoms of sluggish cognitive tempo (SCT) are correlated with inattention and internalizing difficulties. The purpose of the present study was to determine whether symptoms of SCT reflect comorbid internalizing disorder with ADHD or a separate syndrome. Method: Using a clinical sample of youth evaluated for behavioral and learning…

Garner, Annie A.; Mrug, Sylvie; Hodgens, Bart; Patterson, Cryshelle

2013-01-01

213

Symptom variability in COPD: a narrative review.  

PubMed

Chronic obstructive pulmonary disease (COPD) has traditionally been considered an inexorably progressive disease, associated with a constant increase of symptoms that occur as the forced expiratory volume in 1 second (FEV1) worsens, only intermittently interrupted by exacerbations. However, this paradigm has been challenged in recent decades by the available evidence. Recent studies have pointed out that COPD-related symptoms are not consistently perceived by patients in the same way, showing not only seasonal variation, but also changes in symptom perception during a week or even within a single day. According to the available data, patients experience the biggest increase in respiratory symptoms during the first hours of the early morning, followed by the nighttime. This variation over time is of considerable importance, since it impacts on daily life activities and health-related quality of life, as measured by a recently developed ad hoc questionnaire. Additionally, recent clinical trials have suggested that the use of rapid-onset long-acting bronchodilators may have an impact on morning symptoms, despite their current use as maintenance treatment for a determined period. Although this hypothesis is to be validated in future long-term clinical trials comparing fast-onset versus slow-onset inhaled drugs in COPD, it may bring forward a new concept of long-term bronchodilator therapy. At the present time, the two available long-acting, fast-onset bronchodilators used in the treatment of COPD are formoterol and the recently marketed indacaterol. Newer drugs have also been shown to have a rapid onset of action in preclinical studies. Health care professionals caring for COPD patients should consider this variation in the perception of symptoms during their clinical interview as a potential new target in the long-term treatment plan. PMID:23687444

Lopez-Campos, Jose Luis; Calero, Carmen; Quintana-Gallego, Esther

2013-01-01

214

Symptom variability in COPD: a narrative review  

PubMed Central

Chronic obstructive pulmonary disease (COPD) has traditionally been considered an inexorably progressive disease, associated with a constant increase of symptoms that occur as the forced expiratory volume in 1 second (FEV1) worsens, only intermittently interrupted by exacerbations. However, this paradigm has been challenged in recent decades by the available evidence. Recent studies have pointed out that COPD-related symptoms are not consistently perceived by patients in the same way, showing not only seasonal variation, but also changes in symptom perception during a week or even within a single day. According to the available data, patients experience the biggest increase in respiratory symptoms during the first hours of the early morning, followed by the nighttime. This variation over time is of considerable importance, since it impacts on daily life activities and health-related quality of life, as measured by a recently developed ad hoc questionnaire. Additionally, recent clinical trials have suggested that the use of rapid-onset long-acting bronchodilators may have an impact on morning symptoms, despite their current use as maintenance treatment for a determined period. Although this hypothesis is to be validated in future long-term clinical trials comparing fast-onset versus slow-onset inhaled drugs in COPD, it may bring forward a new concept of long-term bronchodilator therapy. At the present time, the two available long-acting, fast-onset bronchodilators used in the treatment of COPD are formoterol and the recently marketed indacaterol. Newer drugs have also been shown to have a rapid onset of action in preclinical studies. Health care professionals caring for COPD patients should consider this variation in the perception of symptoms during their clinical interview as a potential new target in the long-term treatment plan. PMID:23687444

Lopez-Campos, Jose Luis; Calero, Carmen; Quintana-Gallego, Esther

2013-01-01

215

Behavioral and Psychological Symptoms of Dementia  

PubMed Central

Behavioral and psychological symptoms of dementia (BPSD), also known as neuropsychiatric symptoms, represent a heterogeneous group of non-cognitive symptoms and behaviors occurring in subjects with dementia. BPSD constitute a major component of the dementia syndrome irrespective of its subtype. They are as clinically relevant as cognitive symptoms as they strongly correlate with the degree of functional and cognitive impairment. BPSD include agitation, aberrant motor behavior, anxiety, elation, irritability, depression, apathy, disinhibition, delusions, hallucinations, and sleep or appetite changes. It is estimated that BPSD affect up to 90% of all dementia subjects over the course of their illness, and is independently associated with poor outcomes, including distress among patients and caregivers, long-term hospitalization, misuse of medication, and increased health care costs. Although these symptoms can be present individually it is more common that various psychopathological features co-occur simultaneously in the same patient. Thus, categorization of BPSD in clusters taking into account their natural course, prognosis, and treatment response may be useful in the clinical practice. The pathogenesis of BPSD has not been clearly delineated but it is probably the result of a complex interplay of psychological, social, and biological factors. Recent studies have emphasized the role of neurochemical, neuropathological, and genetic factors underlying the clinical manifestations of BPSD. A high degree of clinical expertise is crucial to appropriately recognize and manage the neuropsychiatric symptoms in a patient with dementia. Combination of non-pharmacological and careful use of pharmacological interventions is the recommended therapeutic for managing BPSD. Given the modest efficacy of current strategies, there is an urgent need to identify novel pharmacological targets and develop new non-pharmacological approaches to improve the adverse outcomes associated with BPSD. PMID:22586419

Cerejeira, J.; Lagarto, L.; Mukaetova-Ladinska, E. B.

2012-01-01

216

Palynology of OGS-6a and OGS-7, two new 2.6 Ma archaeological sites from Gona, Afar, Ethiopia: Insights on aspects of Late Pliocene habitats and the beginnings of stone-tool use  

Microsoft Academic Search

Fossil pollen grains extracted from sediments sampled from OGS-6a and OGS-7, two newly excavated Late Pliocene sites of Gona, in the Afar Depression of Ethiopia, indicate a high percentage of afromontane forest and highland taxa (36.8–43.3%), among which Podocarpus cf. gracilor is dominant (19.6–24.2%). Forest taxa typical of the afromontane phytogeographic region have also been identified in the samples. The

José-Antonio López-Sáez; Manuel Domínguez-Rodrigo

2009-01-01

217

Clinical evaluation of early cognitive symptoms.  

PubMed

The etiology of cognitive impairment in older adults is almost always a clinical diagnosis without definitive biomarkers. The clinical evaluation, therefore, is indispensable. Evaluating cognitive symptoms requires a deliberate approach to define the onset, course, and nature of symptoms. An informant who knows the patient well is essential. The physician must have a working knowledge of the basics of cognitive function. The neurologic examination also is fundamental to defining the origin of cognitive impairment. Extraocular movements, speech, and gait are examples of high-yield examination findings that can be observed and tested quickly, adding to the clinical impression. PMID:24094297

McCarten, J Riley

2013-11-01

218

2013/2014 Western OGS Application Handbook This document provides a visual presentation of Western's new online Ontario Graduate Scholarship  

E-print Network

2013/2014 Western OGS Application Handbook This document provides a visual presentation of Western access, this page becomes the Applicant's homepage, headlined with a visual reminder of how far along

Sinnamon, Gordon J.

219

Symptom prevalence, characteristics and distress in a cancer population  

Microsoft Academic Search

Despite the importance of symptom control in the cancer population, few studies have systematically assessed the prevalence and characteristics of symptoms or the interactions between various symptom characteristics and other factors related to quality of life (QOL). As part of a validation study of a new symptom assessment instrument, inpatients and out-patients with prostate, colon, breast or ovarian cancer were

R. K. Portenoy; H. T. Thaler; A. B. Kornblith; J. McCarthy Lepore; H. Friedlander-Klar; N. Coyle; T. Smart-Curley; N. Kemeny; L. Norton; W. Hoskins; H. Scher

1994-01-01

220

Obsessive-Compulsive Spectrum Disorder Symptoms in College Students  

Microsoft Academic Search

Objective: This study investigated the occurrence of obsessive-compulsive spectrum disorders (OCSDs) and associated symptomology in college students. Participants: Participants included 358 undergraduate students. Results: Results suggest that clinically significant levels of OCSD symptoms are relatively common. Additionally, OCSD symptoms co-occurred with each other and anxiety symptoms in general, yet not significantly with impulsivity symptoms. Conclusions: Given their prevalence in college

Michael L. Sulkowski; Amy Mariaskin; Eric A. Storch

2011-01-01

221

Symptom management research in cancer patients: state of the art  

Microsoft Academic Search

AbstractBoth physical symptoms (eg, pain, fatigue, insomnia) and psychological symptoms (eg, depression, anxiety) are prevalent in all types and stages of cancer, from newly diagnosed patients to disease-free cancer survivors to individuals with recurrent or progressive disease. Also, patients often have multiple symptoms, so programmes that focus on single symptoms often fail to optimize treatment outcomes. Additionally, effective treatments include

K Kroenke

2011-01-01

222

Periodontal (Gum) Disease Causes, Symptoms, and Treatments  

E-print Network

Periodontal (Gum) Disease Causes, Symptoms, and Treatments U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health #12;Periodontal (Gum) Disease If you have been told you have periodontal (gum) disease, you're not alone. Many adults in the U.S. currently have some form of the disease

Bandettini, Peter A.

223

The structure of obsessive-compulsive symptoms  

Microsoft Academic Search

In the present study, the structure of obsessive-compulsive symptoms was investigated by means of the Padua Inventory (PI). Simultaneous Components Analysis on data from obsessive-compulsives (n = 206), patients with other anxiety disorders (n = 222), and a non clinical sample (n = 430) revealed a five-factor solution. These factors are: (I) impulses; (II) washing; (III) checking; (IV) rumination; and

Patricia Van Oppen; Rense J. Hoekstra; Paul M. G. Emmelkamp

1995-01-01

224

Behavioral symptoms related to cognitive impairment  

PubMed Central

Neuropsychiatric symptoms (NPS) are core features of Alzheimer’s disease and related dementias. On one hand, behavioral symptoms in patients with mild cognitive impairment (MCI) can indicate an increased risk of progressing to dementia. On the other hand, mild behavioral impairment (MBI) in patients who usually have normal cognition indicates an increased risk of developing dementia. Whatever the cause, all dementias carry a high rate of NPI. These symptoms can be observed at any stage of the disease, may fluctuate over its course, are a leading cause of stress and overload for caregivers, and increase rates of hospitalization and early institutionalization for patients with dementia. The clinician should be able to promptly recognize NPI through the use of instruments capable of measuring their frequency and severity to support diagnosis, and to help monitor the treatment of behavioral symptoms. The aims of this review are to describe and update the construct ‘MBI’ and to revise the reported NPS related to prodromal stages of dementia (MCI and MBI) and dementia stages of Alzheimer’s disease and frontotemporal lobar degeneration. PMID:24092982

Dillon, Carol; Serrano, Cecilia M; Castro, Diego; Leguizamón, Patricio Perez; Heisecke, Silvina L; Taragano, Fernando E

2013-01-01

225

Signs and Symptoms of Wilms Tumor  

MedlinePLUS

... Find Support & Treatment Explore Research Get Involved Find Local ACS Learn About Cancer » Wilms Tumor » Detailed Guide » Signs and symptoms of ... Making Strides Against Breast Cancer Walks Coaches vs. Cancer Relay For Life Events College Relay For ... Offices Volunteer Employment Become a Supplier Report Fraud ...

226

Common gastrointestinal symptoms: irritable bowel syndrome.  

PubMed

The diagnosis of irritable bowel syndrome (IBS) should be considered when patients have had abdominal pain/discomfort, bloating, and change in bowel habits for 6 months. Patients may experience variation between periods of constipation and diarrhea. When evaluating patients with IBS, physicians should be alert for red flag symptoms, such as rectal bleeding, anemia, nighttime pain, and weight loss. Physicians also should consider other medical conditions that manifest similarly to IBS. Clinicians who are confident in diagnosing IBS based on symptoms typically do not obtain many tests unless the patient has red flag symptoms. Various etiologic mechanisms have been proposed for IBS, including abnormal bowel motility, inflammation, altered mucosal permeability, genetic predisposition, and visceral hypersensitivity. Lack of certainty about the etiology makes it difficult to develop effective management approaches; thus, management is directed toward symptom relief. Dietary changes, such as avoiding fermentable carbohydrates, may benefit some patients, especially those with bloating. Constipation-dominant IBS can be managed with antispasmodics, lubiprostone, or linaclotide, whereas diarrhea-dominant IBS can be managed with loperamide or alosetron, though the latter drug can cause ischemic colitis. For long-term therapy, tricyclic antidepressants or selective serotonin reuptake inhibitors have good efficacy. Peppermint oil and probiotics also may provide benefit. PMID:24124703

Fashner, Julia; Gitu, Alfred Chege

2013-10-01

227

Teacher Awareness of Anxiety Symptoms in Children  

Microsoft Academic Search

The present study aimed to determine which anxiety symptoms in children are associated with teacher awareness and whether teacher awareness differs according to student age and gender. The Multidimensional Anxiety Scale for Children (MASC) was completed by 453 second through fifth grade students and teachers nominated the three most anxious students in their classrooms. A multivariate analysis of variance was conducted

Ann E. Layne; Gail A. Bernstein; John S. March

2006-01-01

228

Depressive Symptoms and Impaired Respiration in Sleep.  

ERIC Educational Resources Information Center

Associations between depression and impaired respiration in sleep are frequently noted clinically. This relationship was documented psychometrically with the Geriatric Depression Scale, a self-report measure of nonsomatic depressive symptoms. Mean values and effect size suggest that impaired respiration in sleep was associated with only relatively…

Bliwise, Donald L.; And Others

1986-01-01

229

What Are the Symptoms of the Flu?  

MedlinePLUS Videos and Cool Tools

... Vaccine Program Office, U.S. Department of Health and Human Services, talks about the symptoms of the flu ... website managed by the U.S. Department of Health & Human Services 200 Independence Avenue, S.W. - Washington, D.C. ...

230

Anorexia Nervosa: Its Symptoms and Possible Cures.  

ERIC Educational Resources Information Center

This document presents a definition and description of anorexia nervosa as a disorder that occurs predominantly in girls and that can affect 1 out of every 250 girls between the ages of 12 and 18 years. The existence of a distorted mental body image among anorexics is discussed and symptoms of the disorder are described, including amenorrhea…

Bingaman, David E.

231

Teacher Stress: Sources, Symptoms and Job Satisfaction.  

ERIC Educational Resources Information Center

A survey of 3,789 teachers in 60 school districts in Ohio and Pennsylvania found, as expected, that feelings of job stress and job satisfaction are inversely related. The survey questionnaire gathered data on teachers' ages and experience, their schools' educational levels and urban or rural location, their job satisfaction, the sources, symptoms,…

Feitler, Fred C.; Tokar, Edward B.

232

Symptoms, Diagnosis and Treatment of Pneumonia  

MedlinePLUS

... F. This pneumonia causes profuse sweating, and rapidly increased breathing and pulse rate. Lips and nailbeds may have a bluish color due to lack of oxygen in the blood. A patient's mental state may be confused or delirious. The initial symptoms ...

233

Acculturation, Ethnicity, and Symptoms of Schizophrenia  

Microsoft Academic Search

Research findings on acculturation and mental health are complex. Previous research has demonstrated mixed results indicating that an increasing level of acculturation can be associated with both detrimental and beneficial health outcomes. Research focusing on the association of acculturation and schizophrenia remains largely unexplored. This study evaluated the relationship between acculturation and symptom severity with 47 Latino, Black, and White

Vamsi K. Koneru; Amy G. Weisman de Mamani

2006-01-01

234

The frequencies of conversion reaction symptoms  

Microsoft Academic Search

Compared the frequencies with which 69 conversion symptoms are described in 18 abnormal psychology and psychiatry textbooks with the frequencies with which they appeared in a sample of 40 male hysterics and a group of female conversion reactions depicted in an earlier study. The correlations were small. Results suggest that textbook descriptions do not focus on the more common conversion

Charles G. Watson; Cheryl Buranen

1979-01-01

235

Prodromal symptoms in skunk Suzanna Hunt  

E-print Network

Volume 1 Prodromal symptoms in skunk Suzanna Hunt D.Clin.Psy. thesis, 2008 University College to explore the effects of "Skunk," a high potency variety of cannabis which now accounts for 81 but little is known about the impact of skunk or whether users experience psychotic-like or prodromal

Jones, Peter JS

236

PUZZLING SYMPTOMS: EATING DISORDERS AND THE BRAIN  

E-print Network

PUZZLING SYMPTOMS: EATING DISORDERS AND THE BRAIN A FAMILY GUIDE TO THE NEUROBIOLOGY OF EATING TO DO WITH THE BRAIN? Although people with eating disorders struggle to eat normally, this is only now believe that part of the problem has to do with how our brains process information about

Squire, Larry R.

237

Psychiatric Symptoms in Alpha-Mannosidosis  

ERIC Educational Resources Information Center

Alpha-mannosidosis is characterized by mild to moderate intellectual disability (ID), moderate to severe neurosensory hearing loss, frequent infections, psychomotor disturbances and skeletal dysmorphism. For the first time, a panel of nine alpha-mannosidosis patients with psychiatric symptoms is presented. The clinical picture has several…

Malm, D.; Pantel, J.; Linaker, O. M.

2005-01-01

238

Does early adolescent sex cause depressive symptoms?  

Microsoft Academic Search

A recent study by the Heritage Foundation (Rector, Johnson, & Noyes, 2003) found evidence of a positive relationship between early sexual intercourse and depressive symptoms. This finding has been used to bolster support for funding abstinenceonly sex education. However, promoting abstinence will only yield mental health benefits if there is a causal link between sexual intercourse and depression. Using the

Joseph J. Sabia

2006-01-01

239

Pink Eye Conjunctivitis Definition, Symptoms and Causes  

E-print Network

Pink Eye ­ Conjunctivitis Definition, Symptoms and Causes Pink eye is the common name given to inflammation of the conjunctiva of the eye. It is otherwise called conjunctivitis. The conjunctiva is the transparent membrane that lines the eyelids and covers the whites of the eyes. Very small, superficial blood

Suzuki, Masatsugu

240

Hoarding and Obsessive-Compulsive Symptoms.  

ERIC Educational Resources Information Center

Researches the relation between hoarding and obsessive-compulsive disorders (OCD). In both college student and community samples, hoarding was associated with higher scores on the Yale-Brown Obsessive-Compulsive Scale. Hoarding also was associated with higher levels of general psychopathology as measured by the Brief Symptom Inventory. Results…

Frost, Randy O.; And Others

1996-01-01

241

Autism and ADHD: Overlapping and Discriminating Symptoms  

ERIC Educational Resources Information Center

Children with ADHD and autism have some similar features, complicating a differential diagnosis. The purpose of our study was to determine the degree to which core ADHD and autistic symptoms overlap in and discriminate between children 2-16 years of age with autism and ADHD. Our study demonstrated that 847 children with autism were easily…

Mayes, Susan Dickerson; Calhoun, Susan L.; Mayes, Rebecca D.; Molitoris, Sarah

2012-01-01

242

Symptoms and signs in fibromyalgia syndrome.  

PubMed

Fibromyalgia syndrome (FM) is a common chronic pain condition that affects at least 2% of the adult population. Chronic widespread pain is the defining feature of FM, but patients may also exhibit a range of other symptoms, including sleep disturbance, fatigue, irritable bowel syndrome, headaches, and mood disorders. The etiology of FM is not completely understood and the syndrome is influenced by factors such as stress, medical illness, and a variety of pain conditions. Establishing diagnosis may be difficult because of the multifaceted nature of the syndrome and overlap with other chronically painful conditions. A unifying hypothesis is that FM results from sensitization of the central nervous system; this new concept could justify the variety of characteristics of the syndrome. FM symptoms can be musculoskeletal, non-musculoskeletal, or a combination of both; and many patients will also experience a host of associated symptoms or conditions. The ACR classification criteria focus only on pain and disregard other important symptoms; but three key features, pain, fatigue and sleep disturbance, are present in virtually every patient with FM. Several other associated syndromes, including circulatory, nervous, digestive, urinary and reproductive systems are probably a part of the so called central sensitivity or sensitization syndrome. A minority subgroup of patients (30-40%) has a significant psychological disturbance. Psychological factors are an important determinant of any type of pain, and psychological comorbidity is frequent in FM. Psychiatric disorders most commonly described are mood disorders, but psychiatric illness is not a necessary factor in the etiopathogenesis of FM. PMID:18852905

Cassisi, G; Sarzi-Puttini, P; Alciati, A; Casale, R; Bazzichi, L; Carignola, R; Gracely, R H; Salaffi, F; Marinangeli, F; Torta, R; Giamberardino, M A; Buskila, D; Spath, M; Cazzola, M; Di Franco, M; Biasi, G; Stisi, S; Altomonte, L; Arioli, G; Leardini, G; Gorla, R; Marsico, A; Ceccherelli, F; Atzeni, F

2008-01-01

243

Political Ideology and Psychological Symptoms Following Terror  

ERIC Educational Resources Information Center

The article examines the associations between political ideology and level of psychological symptoms in youth exposed to terror attacks. The study included 2,999 7th to 10th graders from various parts of Israel. Political ideology was examined in two ways: (a) as a content dimension: "political stand"--holding right, centrist, or left wing views…

Laufer, Avital; Solomon, Zahava

2010-01-01

244

Caregiving, residence, race, and depressive symptoms  

PubMed Central

The objective of this study is to evaluate the psychological responses to caregiving between black and white dementia caregivers measured by self-reports of depressive symptoms evaluating the impact of sub-components of the Center for Epidemiologic Studies Depression Scale (CES-D) and residential arrangements of the caregiving dyad. The method included 87 intergenerational family caregivers enrolled in the Duke Caregiver Study (50 white and 37 black). Total CES-D and the four sub-components were modeled as dependent measures in separate linear regressions. Three models were examined. The first model tested race, living arrangements, and their interaction. The second model adjusted for age, gender, education, income, health status, cultural justification for caregiving, crime concerns, systolic blood pressure, diastolic blood pressure, and glycosylated hemoglobin. A third model added adjustment for caregiver burden. The results showed that there was a significant race by residence interaction for CES-D, somatic symptoms and depressive affect such that when the dyads are living apart – with the care recipient in their own home or in an institutional setting – whites reported more depressive symptoms than blacks. When the dyads lived together, this was reversed, and blacks reported higher depressive symptoms than whites. To conclude, all the parameters such as race, living arrangements, and the components of depression need to be taken into account to understand the impact of caregiving on the emotional health of caregivers. PMID:20635234

Siegler, Ilene C.; Brummett, Beverly H.; Williams, Redford B.; Haney, Thomas L.; Dilworth-Anderson, Peggye

2011-01-01

245

Anxiety disorder symptoms in chinese preschool children.  

PubMed

The present study investigated anxiety disorder symptoms in Chinese preschool children. A total of 1,854 mothers of children aged 3-6 years completed the 28-item Chinese version of Spence Preschool Anxiety Scale (PAS). Results demonstrated that the structure of anxiety in Chinese preschool children included five factors, and this five-factor structure applied to different age and gender groups. Inconsistent with the study by Edwards et al. (J Clin Child Adolesc Psychol 39:400-409, 2010) suggesting that obsessive-compulsive disorder did not comprise an independent factor in Australian preschoolers, this symptom can be viewed as an independent factor in Chinese preschoolers. Younger children displayed higher anxiety levels than older children. Anxiety symptoms of Chinese preschoolers were found at a high level compared to other studies. Substantial differences were found with regard to the content of prevalent anxiety symptoms among Chinese and Australian preschool children. The applicability of the five-factor structure of PAS and research implications are discussed. PMID:24668567

Wang, Meifang; Zhao, Jinxia

2015-02-01

246

Assessment of migraine-related cochleovestibular symptoms.  

PubMed

The objective was to assess the cochleovestibular symptoms in migraine. Therefore, a questionnaire form was prepared to record the data obtained from 20 migraineurs. All patients were assessed with audiometry, bithermal caloric testing and auditory brainstem response testing (ABR) between the migraine attacks, and 8 of them were also assessed during the attacks. Dizziness (30%) was the most common symptom that was followed by vertigo (25%) and tinnitus (20%). All patients had hearing within normal limits. Positional test (Hallpike maneuver) was positive in 2 (10%). Bithermal caloric testing revealed canal paresis in 3 (15%) patients. ABR results were normal in 13 patients. Seven patients (35%) had abnormal ABR results. Four of them (20%) had elongation in the absolute wave latencies (wave I, III and V) and normal IPLs of wave I-III, III-V and I-V. Three (15%) patients had elongation in the absolute wave latencies as well as in the IPLs of wave I-III, III-V and I-V. In conclusion, cochleovestibular symptoms can be seen in migraineurs. The test results between and during attacks are similar. The subjective cochleovestibular symptoms did not correlate with the objective tests performed (audiometry, ABR and caloric testing). PMID:11715266

Bayazit, Y; Yilmaz, M; Mumbuç, S; Kanlikama, M

2001-01-01

247

Does Early Adolescent Sex Cause Depressive Symptoms?  

ERIC Educational Resources Information Center

A recent study by the Heritage Foundation (Rector, Johnson, & Noyes, 2003) found evidence of a positive relationship between early sexual intercourse and depressive symptoms. This finding has been used to bolster support for funding abstinence only sex education. However, promoting abstinence will only yield mental health benefits if there is a…

Sabia, Joseph J.

2006-01-01

248

Transient Neurologic Symptoms After Spinal Anesthesia  

Microsoft Academic Search

- We recently reported several cases consistent with tran- sient radicular irritation after spinal anesthesia with hy- perbaric 5% lidocaine. The present prospective, blind, nonrandomized study was performed to determine the incidence of these transient neurologic symptoms and to identify factors that might be associated with their occurrence. We studied 270 patients scheduled for gy- necologic or obstetric procedures under

Karl F. Hampl; Markus C. Schneider; Wolfgang Ummenhofer; Jurgen Drewe

1995-01-01

249

Experimental investigation of the effects of naturalistic dieting on bulimic symptoms: moderating effects of depressive symptoms.  

PubMed

Prospective studies suggest that dieting increases risk for bulimic symptoms, but experimental trials indicate dieting reduces bulimic symptoms. However, these experiments may be unrepresentative of real-world weight loss dieting. In addition, the fact that most dieters do not develop eating disorders suggests moderating factors may be important. Accordingly, we randomly assigned 157 female intermittent dieters to either diet as they usually do for weight loss or eat as they normally do when not dieting for 4 weeks. Naturalistic dieting halted the weight gain shown by controls, but did not result in significant weight loss. Although there was no main effect of the dieting manipulation on bulimic symptoms, moderation analyses indicated that naturalistic dieting decreased bulimic symptoms among participants with initially low depressive symptoms. Results suggest that self-initiated weight loss dieting is not particularly effective, which appears to explain several discrepancies in the literature. Additionally, depressive symptoms may be an important determinant of bulimic symptoms that eclipses the effects of naturalistic dieting on this outcome. PMID:17662503

Presnell, Katherine; Stice, Eric; Tristan, Jennifer

2008-01-01

250

Surgical Model of Menopause Symptoms: GABA'S Role in Anxiety and Hot Flashes Anna Frink1  

E-print Network

Surgical Model of Menopause Symptoms: GABA'S Role in Anxiety and Hot Flashes Anna Frink1 1 agonist at the benzodiazepine site on the GABAA receptor) following bilateral ovariectomy. Previous work-operated control rats. However, the neural sites that mediate this response are unknown. We hypothesized

Zhou, Yaoqi

251

Functional Impairments as Symptoms in the Symptom Cluster Analysis of Patients Newly Diagnosed With Advanced Cancer  

PubMed Central

Context Symptoms and subsequent functional impairment have been associated with the biological processes of a disease, including the interaction between the disease and treatment in a measurement model of symptoms. However, hitherto cluster analysis has primarily focused on symptoms. Objectives This study among patients within 100 days of diagnosis with advanced cancer explored whether self-reported physical symptoms and functional impairments formed clusters at the time of diagnosis. Methods We applied the cluster analysis to self-reported symptoms and activities of daily living of 111 patients newly diagnosed with advanced gastrointestinal (GI), gynecological, head and neck, and lung cancers. Based on the content, expert evaluations, the best techniques, variables were identified, yielding the best solution. Results The best cluster solution used a K-means algorithm and cosine similarity and yielded five clusters of physical as well as emotional symptoms and functional impairments. Cancer site formed the predominant organizing principle of composition for each cluster. The top five symptoms and functional impairments in each cluster were Cluster 1 (GI): outlook, insomnia, appearance, concentration, and eating/feeding; Cluster 2 (GI): appetite, bowel, insomnia, eating/feeding, and appearance; Cluster 3 (gynecological): nausea, insomnia, eating/feeding, concentration, and pain; Cluster 4 (head and neck): dressing, eating/feeding, bathing, toileting, and walking; and Cluster 5 (lung): cough, walking, eating/feeding, breathing, and insomnia. Conclusion Functional impairments in patients newly diagnosed with late-stage cancers behave as symptoms during the diagnostic phase. Health care providers need to expand their assessments to include both symptoms and functional impairments. Early recognition of the functional changes may accelerate diagnosis at an earlier cancer stage. PMID:23380336

Fodeh, Samah J.; Lazenby, Mark; Bai, Mei; Ercolano, Elizabeth; Murphy, Terrence; McCorkle, Ruth

2015-01-01

252

Predictors of posttraumatic stress symptoms following childbirth  

PubMed Central

Background Posttraumatic stress disorder (PTSD) following childbirth has gained growing attention in the recent years. Although a number of predictors for PTSD following childbirth have been identified (e.g., history of sexual trauma, emergency caesarean section, low social support), only very few studies have tested predictors derived from current theoretical models of the disorder. This study first aimed to replicate the association of PTSD symptoms after childbirth with predictors identified in earlier research. Second, cognitive predictors derived from Ehlers and Clark’s (2000) model of PTSD were examined. Methods N = 224 women who had recently given birth completed an online survey. In addition to computing single correlations between PTSD symptom severities and variables of interest, in a hierarchical multiple regression analyses posttraumatic stress symptoms were predicted by (1) prenatal variables, (2) birth-related variables, (3) postnatal social support, and (4) cognitive variables. Results Wellbeing during pregnancy and age were the only prenatal variables contributing significantly to the explanation of PTSD symptoms in the first step of the regression analysis. In the second step, the birth-related variables peritraumatic emotions and wellbeing during childbed significantly increased the explanation of variance. Despite showing significant bivariate correlations, social support entered in the third step did not predict PTSD symptom severities over and above the variables included in the first two steps. However, with the exception of peritraumatic dissociation all cognitive variables emerged as powerful predictors and increased the amount of variance explained from 43% to a total amount of 68%. Conclusions The findings suggest that the prediction of PTSD following childbirth can be improved by focusing on variables derived from a current theoretical model of the disorder. PMID:25026966

2014-01-01

253

Restenosis and symptom recurrence after endovascular therapy for claudication: Does duplex ultrasound correlate with recurrent claudication?  

PubMed

After endovascular therapy, duplex ultrasound surveillance to detect restenosis guides clinical decisions and defines treatment failure. However, the correlation between duplex ultrasound and symptom recurrence remains unclear. We reviewed our institutional experience (2007-2010) to identify patients undergoing endovascular therapy for claudication. The association between post-intervention systolic velocity ratio and patient-reported symptom recurrence was determined. We analyzed 183 follow-up visits following treatment in 88 limbs (femoropopliteal (56%) or iliac (44%) arteries). After femoropopliteal intervention, median systolic velocity ratio was higher in patients with symptom recurrence (2.99 symptomatic vs. 1.69 asymptomatic; p?symptom recurrence (area under receiver operator characteristic curve?=?0.82 [95% CI 0.74-0.83]), and systolic velocity ratio?>2.5 was 71% sensitive and 72% specific for symptom recurrence. After femoropopliteal endovascular therapy for claudication, duplex ultrasound-detected restenosis is highly associated with clinical deterioration. This validates objective criteria for treatment failure in claudicants and suggests that symptom status can serve as a primary indicator of anatomic restenosis. PMID:24788064

Jones, Douglas W; Graham, Ashley; Connolly, Peter H; Schneider, Darren B; Meltzer, Andrew J

2015-02-01

254

Relation between personality dimensions and depressive symptoms in patients on hemodialysis.  

PubMed

The aim of the study was to investigate the relationship between the presence of depressive symptoms and certain dimensions of personality in hemodialysis patients. The study included 93 subjects of both sexes, aged 24-78 years. All subjects were undergoing hemodialysis treatment for terminal stage renal insufficiency. The presence of depressive symptoms was operationally defined by the factor scores for the first principal components on the Beck Depression Inventory. Five personality dimensions were operationally defined by the factor scores for the first principal components on each of the five scales of the Big Five Inventory. The following dimensions of personality were assessed: neuroticism, extraversion, openness, agreeableness, and conscientiousness. The relationship between the five dimensions of personality and the presence of depressive symptoms was analyzed by the multiple regression analysis. The results showed that personality dimensions are significantly connected with the occurrence of depressive symptoms (R = 0.729; R2 = 0.532; F (5,87) = 19.822; p = 0.000). Two partial predictors were significantly connected with depressive symptoms. They were higher degree of neuroticism (beta = 0.082, p = 0.000) and a lower degree of openness (beta = -0.235, p = 0.016). PMID:21180270

Bugarski, Vojislava; Sakac, Vladimir; Vodopivec, Slavenka; Slankamenac, Petar

2010-01-01

255

OG 1.2.18 1 Single hadrons in Milagro and the Spectrum of Cosmic Ray  

E-print Network

OG 1.2.18 1 Single hadrons in Milagro and the Spectrum of Cosmic Ray Protons Gaurang B. Yodh 1 of the Technique: At high energies (energies above a few TeV) most cosmic rays produce air showers at the Milagro of the incident cosmic ray are located within few meters of the core of the shower. A fraction exp( \\Gammax â??(E

California at Santa Cruz, University of

256

Acupuncture Alleviated the Nonmotor Symptoms of Parkinson's Disease including Pain, Depression, and Autonomic Symptoms  

PubMed Central

A woman started to feel intractable pain on her lower legs when she was 76. At the age of 78, she was diagnosed as having Parkinson's disease (PD). The leg pain was suspected to be a symptom of PD after eliminating other causes. The patient also suffered from nonmotor symptoms, depression, anxiety, hot flashes, and paroxysmal sweating. Though the patient had received pharmacotherapy including levodopa for 5 years, she still suffered from the nonmotor symptoms and was referred to our department. We treated her with acupuncture based on the Chinese traditional medicine and electroacupuncture five times per week. After the 2-week treatment, the assessment for the symptoms was as follows; visual analogue scale (VAS) score of the leg pain was 16?mm (70?mm, before), Hamilton's rating scales for depression (HAM-D) score was 9 (18, before), timed 3?m Up and Go took 20 steps in 30?sec (24 steps in 38?sec, before), and the Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Part 1 score was 13 (21, before). Autonomic symptoms, hot flashes and paroxysmal sweating, were also alleviated. Acupuncture may be a good treatment modality for nonmotor symptoms in PD. PMID:25628905

Iseki, Chifumi; Furuta, Taiga; Suzuki, Masao; Koyama, Shingo; Suzuki, Keiji; Suzuki, Tomoko; Kaneko, Akiyo

2014-01-01

257

Acupuncture for Cancer Pain and Related Symptoms  

PubMed Central

Cancer pain is one of most prevalent symptoms in patients with cancer. Acupuncture and related techniques have been suggested for the management of cancer pain. The National Comprehensive Cancer Network (NCCN®) guidelines for adult cancer pain recommends acupuncture, as one of integrative interventions, in conjunction with pharmacologic intervention as needed. This review presents the latest available evidence regarding the use of acupuncture for cancer pain. It also provides “actionable” acupuncture protocols for specific cancer pain conditions and related symptoms in order to provide more clinically relevant solutions for clinicians and cancer patients with pain. These conditions include postoperative cancer pain, postoperative nausea and vomiting, postsurgical gastroparesis syndrome, opioid-induced constipation, opioid-induced pruritus, chemotherapy-induced neuropathy, aromatase inhibitor-associated joint pain, and neck dissection-related pain and dysfunction. PMID:23338773

Lu, Weidong; Rosenthal, David S

2013-01-01

258

Asthma and other symptoms in cinnamon workers.  

PubMed Central

Cinnamon, which is the bark of the Cinnamomum zeylanicum tree, contains cinnamic aldehyde, which is an irritant. Workers processing cinnamon before export are exposed to much cinnamon dust. Forty such workers with an average of four years' service in the industry were examined. Thirty five workers (87.5%) had symptoms, nine having had asthma (22.5%). Other symptoms, probably related to the irritant nature of cinnamon dust, were irritation of skin (50%), loss of hair (37.5%), and smarting of eyes while at work (22.5%). Loss of weight (65%) was the commonest finding. Contact dermatitis which has previously been described was not found in any of the workers. PMID:6232942

Uragoda, C G

1984-01-01

259

Symptoms of annular pancreas exacerbated by pregnancy.  

PubMed

Annular pancreas is a rare embryonal abnormality. Its manifestation in adulthood is often pinpointed with a substantial delay, which is most often attributed to pancreatitis, biliary pathology or dyspepsia. We present a case of a 28-year-old woman who had exacerbating symptoms of high bowel obstruction from 20th week of pregnancy, progressing after premature delivery. Diagnostic work-up revealed partial annular pancreas compressing the duodenum. Despite attempts of conservative treatment, her state deteriorated to such an extent that surgery was indicated and gastrojejunal bypass created. Her postoperative recovery was uneventful. In cases in which symptoms of high bowel obstruction in pregnancy persist and prostration occurs, we suggest close monitoring and a more thorough diagnostic approach. The question remains whether annular pancreas presents a cause of pathologic findings, a cofactor, or a mere accidental diagnosis in the development of superposed pathologies. PMID:19623872

Ledinsky, Mario; Sui?, Ivan; Babi?, Nenad; Kujundzi?, Stipan

2009-03-01

260

Levodopa unresponsive symptoms in Parkinson disease.  

PubMed

Levodopa has been the mainstay of symptomatic therapy for Parkinson Disease (PD) for 40 years providing benefit to virtually all patients. Levodopa therapy results in improved activities of daily living, enhanced quality of life, and improved mortality. However, the long-term use of levodopa is associated with the development of motor fluctuations and dyskinesia. In addition, levodopa therapy has further limitations. It has little or no effect on certain motor features (e.g. gait and balance dysfunction) and a non-motor symptom complex (autonomic dysfunction, pain syndromes, sleep disorders, mood disturbances, dementia). Further, multiple case reports illustrate the potential of levodopa and other dopaminergic agents to cause or reveal a series of impulse control disorders. This review highlights the levodopa unresponsive symptoms in PD. PMID:18781679

Sethi, Kapil

2008-01-01

261

Personality Disorder Symptoms and Marital Functioning  

PubMed Central

Pathological personality is strongly linked with interpersonal impairment, yet, no study to date has examined the relationship between concurrent personality pathology and dysfunction in marriage—a relationship most people find central to their lives. In a cross-sectional study of a community sample of married couples (N=82), multilevel modeling was used to estimate the association of self- and spouse reported PD symptoms with levels of marital satisfaction and verbal aggression and perpetration of physical violence. Including self- and spouse report of total PD symptoms resulted in improved model fit and greater variance explained, with much of the improvement coming after the addition of spouse-report. The incremental validity of spouse-report of several of the ten PD scales was supported for marital satisfaction and verbal aggression, particularly for borderline and dependent PD features. PMID:18837594

South, Susan C.; Turkheimer, Eric; Oltmanns, Thomas F.

2008-01-01

262

Modeling the Temporal Complexities of Symptoms  

Microsoft Academic Search

ObjectiveTo analyze the temporal aspects of symptoms, including their temporal uncertainty, in order to develop a high-level conceptual data model representation of this domain.DesignA basic tenet of existing temporal models is that events occur not only relative to a particular date or time, but also relative to the time of some other event. The time an event occurs, particularly when

Robert H Dolin

1995-01-01

263

Residual symptoms and comorbidity in panic disorder  

Microsoft Academic Search

Background: The aim of this study was to assess the outcome of the comorbid conditions of panic disorder after 1 year of treatment, emphasizing the detection of residual symptoms and their relationship to other clinical variables. Methods: Subjects (N = 64) were assessed by the Structured Clinical Interview for DSM-III-R and the Eysenck Personality Questionnaire. Comorbidity with other disorders, scores on Hamilton Anxiety

Antoni Corominas; Tina Guerrero; Julio Vallejo

2002-01-01

264

Waiting for Symptoms - Gut-Check  

Cancer.gov

Your doctor may talk to you about “watchful waiting” as an approach for other medical situations. Unfortunately, this isn’t an option when it comes to colorectal cancer. Many people with colon cancer don’t experience symptoms until it’s too late. The recommended screening methods can find cancer or pre-cancerous polyps early, when they can be treated and removed. That’s why having a screening plan is important.

265

Perfectionism and Obsessive-Compulsive Symptoms  

Microsoft Academic Search

This study was designed to determine whether perfectionism, as assessed by the revised almost perfect scale (APS-R; R. B.\\u000a Slaney, M. Mobley, J. Trippi, J. S. Ashby, & D. G. Johnson, 1996), was a significant predictor of obsessive-compulsive (OC)\\u000a symptoms in a non-clinical sample of 308 university students. Perfectionistic discrepancy emerged as a general predictor of\\u000a obsessive thought difficulties and

Kenneth G. Rice; Steven L. Pence

2006-01-01

266

Hoarding and Obsessive-Compulsive Symptoms  

Microsoft Academic Search

The present study attempts to extend recent research on the relation between hoarding and obsessive-compulsive experiences. In both college student and community samples, hoarding was associated with higher scores on the Yale-Brown Obsessive-Compulsive Scale (YBOCS). The relationship was stronger among the community sample, in which there was a greater range of compulsive symptoms and hoarding behavior. Hoarding was also associated

Randy O. Frost; Meredith S. Krause; Gail Steketee

1996-01-01

267

Somatic symptoms and health-related quality of life among treatment-seeking Canadian Forces personnel with PTSD.  

PubMed

This study examined the association between somatic complaints and health-related quality of life (HR-QoL) in treatment-seeking Canadian military personnel with military-related Posttraumatic Stress Disorder (PTSD). Current and former Canadian Forces (CF) members attending the Parkwood Hospital Operational Stress Injury Clinic in London, Ontario (N=291) were administered self-report questionnaires assessing number and severity of somatic complaints, PTSD and depressive symptom severity, and mental and physical health-related quality of life (HR-QoL) prior to commencing treatment. Regression analyses were used to identify the role of somatic complaints on physical and mental HR-QoL, after controlling for PTSD symptom cluster and depressive symptom severity. Somatic symptom severity accounted for only a small amount of the variance in mental HR-QoL after accounting for PTSD symptom cluster and depressive symptom severity, but accounted for a larger proportion of the variance in physical HR-QoL after accounting for PTSD cluster and depressive symptom severity. Understanding the role of somatization in the symptom-presentation of military personnel with PTSD may provide additional avenues for treatment with this population. PMID:24745465

St Cyr, Kate; McIntyre-Smith, Alexandra; Contractor, Ateka A; Elhai, Jon D; Richardson, J Don

2014-08-15

268

Discrimination hurts, but mindfulness may help: Trait mindfulness moderates the relationship between perceived discrimination and depressive symptoms  

PubMed Central

Discriminatory experiences are not only momentarily distressing, but can also increase risk for lasting physical and psychological problems. Specifically, significantly higher rates of depression and depressive symptoms are reported among people who are frequently the target of prejudice. Given the gravity of this problem, this research focuses on an individual difference, trait mindfulness, as a protective factor in the association between discrimination and depressive symptoms. In a community sample of 605 individuals, trait mindfulness dampens the relationship between perceived discrimination and depressive symptoms. Additionally, mindfulness provides benefits above and beyond those of positive emotions. Trait mindfulness may thus operate as a protective individual difference for targets of discrimination. PMID:24347755

Brown-Iannuzzi, Jazmin L.; Adair, Kathryn C.; Payne, B. Keith; Richman, Laura Smart; Fredrickson, Barbara L.

2013-01-01

269

Neuroticism, depressive symptoms, and serum BDNF  

PubMed Central

Objective Animal models and clinical studies suggest that brain-derived neurotrophic factor (BDNF) is involved in the pathophysiology of depression. We test whether serum and plasma levels of BDNF are associated with trait Neuroticism and its facets, and with state measure of depressive symptoms. Method In a community-based cohort (N = 2099) we measured serum and plasma BDNF concentration, administered the Revised NEO Personality Inventory (NEO-PI-R) and the Center for Epidemiologic Studies Depression Scale (CES-D). Covariates included age, sex, cigarette smoking, obesity, and antidepressant use. Results Serum BDNF concentrations were inversely related to Neuroticism (r = ?0.074, P < 0.001), in particular the Depression facet (r = ?0.08, P < 0.001). Lower BDNF concentrations were also associated with severe depressive symptoms (CES-D ? 28; OR = 0.906; 95%CI = 0.851–0.965). The association of serum BDNF with Neuroticism was independent of depressive symptoms, indicating that serum BDNF might represent a biological correlate of Neuroticism and not just of transient depressive states. Plasma BDNF was not associated with measures of depression. Conclusions Our study suggests that lower serum BDNF is associated with both a dispositional vulnerability to depression and acute depressive states in the general population. PMID:21949427

Terracciano, Antonio; Lobina, Monia; Piras, Maria Grazia; Mulas, Antonella; Cannas, Alessandra; Meirelles, Osorio; Sutin, Angelina R.; Zonderman, Alan B; Uda, Manuela; Crisponi, Laura; Schlessinger, David

2011-01-01

270

Ectopic expression of ubiquitin-conjugating enzyme gene from wild rice, OgUBC1, confers resistance against UV-B radiation and Botrytis infection in Arabidopsis thaliana  

SciTech Connect

Highlights: Black-Right-Pointing-Pointer We isolated a novel E2 ubiquitin-conjugating enzyme from leaves of wild rice plants. Black-Right-Pointing-Pointer The OgUBC1 was highly expressed in leaves treated with SA and UV-B radiation. Black-Right-Pointing-Pointer The recombinant OgUBC1 has an enzymatic activity of E2 in vitro. Black-Right-Pointing-Pointer The OgUBC1 could protect disruption of plant cells by UV-B radiation. Black-Right-Pointing-Pointer OgUBC1 confers disease resistance and UV-B tolerance in transgenic Arabidopsis plants. -- Abstract: A previously unidentified gene encoding ubiquitin-conjugating enzyme was isolated from leaves of wild rice plant treated with wounding and microbe-associated molecular patterns. The OgUBC1 gene was composed of 148 amino acids and contained a typical active site and 21 ubiquitin thioester intermediate interaction residues and 4 E3 interaction residues. Both exogenous application of salicylic acid and UV-B irradiation triggered expression of OgUBC1 in leaves of wild rice. Recombinant OgUBC1 proteins bound to ubiquitins in vitro, proposing that the protein might act as E2 enzyme in planta. Heterologous expression of the OgUBC1 in Arabidopsis thaliana protected plants from cellular damage caused by an excess of UV-B radiation. A stable expression of chalcone synthase gene was detected in leaves of OgUBC1-expressing Arabidopsis, resulting in producing higher amounts of anthocyanin than those in wild-type Col-0 plants. Additionally, both pathogenesis-related gene1 and 5 were transcribed in the transgenic Arabidopsis in the absence of pathogen infection. The OgUBC1-expressing plants were resistant to the infection of Botrytis cinerea. Taken together, we suggested that the OgUBC1 is involved in ubiquitination process important for cellular response against biotic and abiotic stresses in plants.

Jeon, En Hee; Pak, Jung Hun; Kim, Mi Jin; Kim, Hye Jeong [Department of Genetic Engineering, Dong-A University, Busan 604-714 (Korea, Republic of)] [Department of Genetic Engineering, Dong-A University, Busan 604-714 (Korea, Republic of); Shin, Sang Hyun [National Crop Experiment Station, Rural Development Administration, Suwon 441-100 (Korea, Republic of)] [National Crop Experiment Station, Rural Development Administration, Suwon 441-100 (Korea, Republic of); Lee, Jai Heon; Kim, Doh Hoon; Oh, Ju Sung [Department of Genetic Engineering, Dong-A University, Busan 604-714 (Korea, Republic of)] [Department of Genetic Engineering, Dong-A University, Busan 604-714 (Korea, Republic of); Oh, Boung-Jun [BioControl Center, Jeonnam 516-942 (Korea, Republic of)] [BioControl Center, Jeonnam 516-942 (Korea, Republic of); Jung, Ho Won, E-mail: hwjung@dau.ac.kr [Department of Genetic Engineering, Dong-A University, Busan 604-714 (Korea, Republic of); Chung, Young Soo, E-mail: chungys@dau.ac.kr [Department of Genetic Engineering, Dong-A University, Busan 604-714 (Korea, Republic of)

2012-10-19

271

On Orbit ISS Oxygen Generation System Operation Status  

NASA Technical Reports Server (NTRS)

The International Space Station (ISS) United States Orbital Segment (USOS) Oxygen Generation System (OGS) has accumulated almost a year of operation at varied oxygen production rates within the US Laboratory Module (LAB) since it was first activated in July 2007. It was operated intermittently through 2009 and 2010, due to filter clogging and acid accumulation in the recirculation loop. Since the installation of a deionizing bed in the recirculation loop in May of 2011 the OGA has been operated continuously. Filters in the recirculation loop have clogged and have been replaced. Hydrogen sensors have drifted apart, and a power failure may have condensed water on a hydrogen sensor. A pump delta pressure sensor failed, and a replacement new spare pump failed to start. Finally, the voltage across the cell stack increased out of tolerance due to cation contamination, and the cell stack was replaced. This paper will discuss the operating experience and characteristics of the OGS, as well as operational issues and their resolution.

Diderich, Greg S.; Polis, Pete; VanKeuren, Steven P.; Erickson, Robert; Mason, Richard

2011-01-01

272

What Are the Signs and Symptoms of COPD?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of COPD? At first, COPD may cause no symptoms or ... Rate This Content: Next >> Featured Video What is COPD? 10/15/2014 The NHLBI "Grand Opportunity" Exome ...

273

What Are the Signs and Symptoms of Cystic Fibrosis?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of Cystic Fibrosis? The signs and symptoms of cystic fibrosis (CF) ... respiratory, digestive, or reproductive systems of the body. Cystic Fibrosis Figure A shows the organs that cystic fibrosis ...

274

Panic symptom clusters differentially predict suicide ideation and attempt.  

PubMed

Increasingly strong evidence links anxiety disorders in general and panic attacks in particular to suicidality. The underlying causes and specifics of this relation, however, remain unclear. The present article sought to begin addressing this question by clarifying the association between panic symptoms and suicidality. Data were sampled from the NESARC epidemiological data set from the US and analyzed as four independently, randomly selected subsets of 1000 individuals using structural equation modeling analyses and replicating results across samples. Evidence is presented for four symptom clusters (cognitive symptoms, respiratory distress, symptoms of alpha and beta adrenergic activation) and the differential association of each with suicidal ideation and attempts. Symptoms of alpha adrenergic activation predicted prior suicide attempt whereas cognitive symptoms predicted prior suicidal ideation. These findings were independent of comorbid major depressive disorder. It is suggested that assessment of suicide risk in the community includes the presentation of cognitive symptoms and symptoms related to alpha adrenergic activation. PMID:24439632

Rappaport, Lance M; Moskowitz, D S; Galynker, Igor; Yaseen, Zimri S

2014-05-01

275

Is It Your Jaw?: A Symptoms Checklist for Temporomandibular Disorders  

MedlinePLUS

... are some key symptoms linked to TMD. Unusual sounds — Clicking, grinding or popping sounds when you open your mouth are common in ... doctor for a final diagnosis. If these symptoms sound familiar, talk to your dentist. He or she ...

276

What Are the Signs and Symptoms of Vasculitis?  

MedlinePLUS

... Weight loss Fatigue (tiredness) General aches and pains Organ- or Body System-Specific Signs and Symptoms Vasculitis can affect specific organs and body systems, causing a range of signs and symptoms. Skin ...

277

What Are the Signs and Symptoms of Hemochromatosis?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of Hemochromatosis? Hemochromatosis can affect many parts of the body ... the disease don't have signs or symptoms. Hemochromatosis Complications If hemochromatosis isn't found and treated ...

278

What Are the Signs and Symptoms of Varicose Veins?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of Varicose Veins? The signs and symptoms of varicose veins include: ... signs of other, more serious conditions. Complications of Varicose Veins Varicose veins can lead to dermatitis (der-ma- ...

279

What Are the Signs and Symptoms of Diabetic Heart Disease?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of Diabetic Heart Disease? Some people who have diabetic heart ... your doctor about your risk of heart failure. Diabetic Cardiomyopathy Diabetic cardiomyopathy may not cause symptoms in ...

280

Warning Signs and Symptoms of Heat-Related Illness  

MedlinePLUS

... Signs and Symptoms Warning Signs and Symptoms of Heat-Related Illness Language: English Español (Spanish) Share Compartir Muscle cramping might be the first sign of heat-related illness, and may lead to heat exhaustion ...

281

What Are the Signs and Symptoms of Sickle Cell Anemia?  

MedlinePLUS

... What Are the Signs and Symptoms of Sickle Cell Anemia? The signs and symptoms of sickle cell ... who have sickle cell anemia. Complications of Sickle Cell Anemia Sickle cell crises can affect many parts ...

282

Attention-Deficit / Hyperactivity Disorder (ADHD): Symptoms and Diagnosis  

MedlinePLUS

... Language: English Español (Spanish) Share Compartir Is it ADHD? Symptoms Checklist Fill out the symptoms checklist and ... diagnose or treat ADHD. DSM-5 Criteria for ADHD People with ADHD show a persistent pattern of ...

283

What Are the Signs and Symptoms of Atherosclerosis?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of Atherosclerosis? Atherosclerosis usually doesn't cause signs and symptoms ... Rate This Content: Next >> Featured Video What is atherosclerosis? 10/14/2014 August 4, 2014 Atherosclerosis Clinical ...

284

Transactional relations between marital functioning and depressive symptoms.  

PubMed

The present study investigated dynamic, longitudinal associations between depressive symptoms and marital processes. Two hundred and ninety-six couples reported on marital satisfaction, marital conflict, and depressive symptoms annually for 3 years. Observational measures of marital conflict were also collected. Results suggested that different domains of marital functioning related to husbands' versus wives' symptoms. For husbands, transactional relations between marital satisfaction and depressive symptoms were identified: High levels of depressive symptoms predicted subsequent decreases in marital satisfaction, and decreased marital satisfaction predicted subsequent elevations in depressive symptoms over time. For wives, high levels of marital conflict predicted subsequent elevations in depressive symptoms over time. Cross-partner results indicated that husbands' depressive symptoms were also related to subsequent declines in wives' marital satisfaction. Results are discussed with regard to theoretical perspectives on the marital functioning-depression link and directions for future research are outlined. PMID:21219284

Kouros, Chrystyna D; Cummings, E Mark

2011-01-01

285

Defining and measuring negative symptoms of schizophrenia in clinical trials.  

PubMed

Recent attention has focused on negative symptoms as a target for new therapeutic approaches including pharmacological agents, medical devices, and psychosocial treatments. Each of these approaches requires an instrument for measuring the severity of negative symptoms as well as changes in severity over time. The instrument selected should provide coverage for the domains of negative symptoms; it should be sensitive to change; it should be reliable and relatively brief; and it should be useful for large international trials. These criteria were used to evaluate a number of older instruments including the Schedule for the Assessment of Negative Symptoms (SANS), the Positive and Negative Symptoms Scale (PANSS), and the Negative Symptom Assessment Scale (NSA). Two newer scales, the Brief Negative Symptom Scale (BNSS) and the Clinical Assessment Interview for Negative Symptoms (CAINS) were developed following a National Institute of Mental Health consensus meeting and addressed some of the shortcomings of earlier instruments. PMID:24275698

Marder, Stephen R; Kirkpatrick, Brian

2014-05-01

286

What Are the Signs and Symptoms of Pneumonia?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of Pneumonia? The signs and symptoms of pneumonia vary from ... have sudden changes in mental awareness. Complications of Pneumonia Often, people who have pneumonia can be successfully ...

287

“Profiles of Depressive Symptoms among African Americans and Caribbean Blacks”  

PubMed Central

Latent profile analysis was used to summarize profiles of depressive symptoms among a nationally representative sample of U.S.-born and Caribbean-born Blacks. Analyses are based on the responses of 4,915 African Americans and Caribbean Blacks from the National Survey of American Life. A high symptoms and a low symptoms class were identified. Age, gender, negative social interaction within the individual's social network (e.g., conflict demands, criticism) and racial discrimination were associated with depressive symptoms in the low symptoms class, whereas socioeconomic status, gender, emotional support and negative interaction were associated with depressive symptoms in the high symptoms class. The findings demonstrate the heterogeneity within the Black population in the USA and the distinct sociodemographic, family network and stress correlates of depressive symptoms for each latent class. PMID:17449157

Chatters, Linda M; Taylor, Robert J; Jackson, James S

2007-01-01

288

Effects of neuregulin-1 genetic variation and depression symptom severity on longitudinal patterns of psychotic symptoms in primary care attendees.  

PubMed

A better understanding of the factors associated with psychotic symptoms could aid early identification and treatment of psychotic disorders. Previous studies have typically utilized cross-sectional study designs and have focused on individuals with psychotic disorders. Thus, examination of promising correlates of psychotic symptoms using longitudinal designs among more broadly defined populations is warranted. Two such correlates are neuregulin-1 (NRG1) genotypic variation and depression symptom severity. Both NRG1 and depression symptom severity have cross-sectional evidence for an association with psychosis but their affect on longitudinal patterns of psychotic symptoms and their potential interaction effects are less clear. Using repeated measures analysis of variance and covariance we modeled the main and interaction effects of NRG1 genotypic variation and depressive symptom severity on longitudinal psychotic symptom patterns in 301 primary care attendees assessed annually over 4 years. One-fifth (19.9%) of the participants reported one or more psychotic symptoms over the 4-year assessment period. We observed a curvilinear (i.e., cubic) association between depression symptom severity at baseline and longitudinal patterns of psychotic symptoms but did not observe a main effect for NRG1 genotypic variation on psychotic symptom patterns. However, NRG1 rs6994992 genotype moderated the curvilinear association between depression symptom severity and psychotic symptom patterns. Specifically, depression symptom severity had less of an effect on longitudinal psychotic symptoms among carriers of the rs6994992 TT genotype compared to CC and CT carriers. Our findings suggest a curvilinear association between depression symptom severity and longitudinal patterns of psychotic symptoms that is moderated by NRG1 genotype. PMID:24123921

Bousman, C A; Potiriadis, M; Everall, I P; Gunn, J M

2014-01-01

289

Depression symptom dimensions as predictors of antidepressant treatment outcome: replicable evidence for interest-activity symptoms  

PubMed Central

Background Symptom dimensions have not yet been comprehensively tested as predictors of the substantial heterogeneity in outcomes of antidepressant treatment in major depressive disorder. Method We tested nine symptom dimensions derived from a previously published factor analysis of depression rating scales as predictors of outcome in 811 adults with moderate to severe depression treated with flexibly dosed escitalopram or nortriptyline in Genome-based Therapeutic Drugs for Depression (GENDEP). The effects of symptom dimensions were tested in mixed-effect regression models that controlled for overall initial depression severity, age, sex and recruitment centre. Significant results were tested for replicability in 3637 adult out-patients with non-psychotic major depression treated with citalopram in level I of Sequenced Treatment Alternatives to Relieve Depression (STAR*D). Results The interest-activity symptom dimension (reflecting low interest, reduced activity, indecisiveness and lack of enjoyment) at baseline strongly predicted poor treatment outcome in GENDEP, irrespective of overall depression severity, antidepressant type and outcome measure used. The prediction of poor treatment outcome by the interest-activity dimension was robustly replicated in STAR*D, independent of a comprehensive list of baseline covariates. Conclusions Loss of interest, diminished activity and inability to make decisions predict poor outcome of antidepressant treatment even after adjustment for overall depression severity and other clinical covariates. The prominence of such symptoms may require additional treatment strategies and should be accounted for in future investigations of antidepressant response. PMID:21929846

Uher, R.; Perlis, R. H.; Henigsberg, N.; Zobel, A.; Rietschel, M.; Mors, O.; Hauser, J.; Dernovsek, M. Z.; Souery, D.; Bajs, M.; Maier, W.; Aitchison, K. J.; Farmer, A.; McGuffin, P.

2013-01-01

290

Impending child abuse. Psychosomatic symptoms in adults as a clue.  

PubMed

Adult patients involved in or threatened by the possibility of committing child abuse may develop acute functional symptoms that result in their seeking emergency medical help. Three cases are presented as examples of this relationship. In two, the functional symptom was paralysis or paresis. In the third, symptoms were more diffuse. Recognition of the association between functional symptoms and child abuse may permit intervention before serious child injury occurs. PMID:576443

Mogielnicki, R P; Mogielnicki, N P; Chandler, J E; Weissberg, M P

1977-03-14

291

Withdrawal symptoms: individual differences and similarities across addictive behaviors  

Microsoft Academic Search

The present study examined withdrawal symptoms and their intensities across a range of traditional and non-traditional addictive substances\\/losses (i.e., alcohol, nicotine, caffeine, food, and social\\/love relationship). Study one administered the Withdrawal Symptom Survey to Alcoholics Anonymous members and college students. Seven symptoms (irritability, restlessness, impatience, anxiousness, trouble concentrating, depression, and anger) were rated in the top 10 of symptom intensity

David G. Gilbert; Brenda O. Gilbert; Vicki L. Schultz

1998-01-01

292

Risk factors for work-related symptoms in northern California office workers  

SciTech Connect

In most episodes of health complaints reported in office buildings in the last-twenty years, causal factors have not been identified. In order to assess risk factors for work-related symptoms in office workers, a reanalysis was performed of previous studies, and an epidemiologic study was conducted. The reanalysis of data, showed remarkable agreement among studies. Air-conditioned buildings were consistently associated with higher prevalence of headache, lethargy, and eye, nose, or throat problems. Humidification was not a necessary factor for this higher prevalence. Mechanical ventilation without air-conditioning was not associated with higher symptom prevalence. A study was conducted among 880 office workers, within 12 office buildings selected without regard to worker complaints, in northern California. A number of factors were found associated with prevalence of work-related symptoms, after adjustment in a logistic regression model for personal, psychosocial, job, workspace, and building factors. Two different ventilation types were associated with increases Ln symptom prevalence, relative to workers in naturally ventilated buildings: mechanical supply and exhaust ventilation, without air conditioning and with operable windows; and air-conditioning with sealed windows. No study buildings were humidified. In both these ventilation types, the highest odds ratios (ORs) found were for skin symptoms (ORs-5.0, 5.6) and for tight chest or difficulty breathing (ORs-3.6, 4.3). Use of carbonless copies or photocopiers, sharing a workspace, carpets, new carpets, new walls, and distance from a window were associated with symptom increases. Cloth partitions and new paint were associated with symptom decreases.

Mendell, M.J.

1991-10-01

293

The Ontario Graduate Scholarship Program The Ontario Graduate Scholarship (OGS) program is designed to encourage excellence in graduate studies at the master's and doc-  

E-print Network

The Ontario Graduate Scholarship Program The Ontario Graduate Scholarship (OGS) program is designed, or are continuing in, an approved graduate program at an Ontario University leading to a master's or doctoral degree NSERC, SSHRC, CIHR or OGSST at the same time as an OGS. 2010-2011 Ontario Graduate Scholarship GRADUATE

Woodgett, Jim

294

Adaptiv hardware innen radar og radarapplikasjoner, Forsvarets forskningsinstitutt, Kjeller Forsvarets forskningsinstitutt (FFI) har mer enn 30 rs erfaring med forskningsarbeider innen radar  

E-print Network

Adaptiv hardware innen radar og radarapplikasjoner, Forsvarets forskningsinstitutt, Kjeller Forsvarets forskningsinstitutt (FFI) har mer enn 30 års erfaring med forskningsarbeider innen radar og radarapplikasjoner. Dette omhandler både passive systemer som brukes for å kartlegge radar scenen, kalt

Sahay, Sundeep

295

Trajectories of Postpartum Maternal Depressive Symptoms and Children's Social Skills  

ERIC Educational Resources Information Center

The vast majority of new mothers experience at least some depressive symptoms. Postpartum maternal depressive symptoms can greatly influence children's outcomes (e.g., emotional, cognitive, language, and social development). However, there have been relatively few longitudinal studies of how maternal depressive symptoms may influence children's…

Wu, Yelena P.; Selig, James P.; Roberts, Michael C.; Steele, Ric G.

2011-01-01

296

Hypnotizability, Posttraumatic Stress, and Depressive Symptoms in Metastatic Breast Cancer  

Microsoft Academic Search

This study assessed whether high hypnotizability is associated with posttraumatic stress and depressive symptoms in a sample of 124 metastatic breast cancer patients. Hypnotic Induction Profile Scores were dichotomized into low and high categories; posttraumatic intrusion and avoidance symptoms were measured with the Impact of Events Scale (IES); hyperarousal symptoms with items from the Profile of Mood States; and depressive

Alex S. Keuroghlian; Lisa D. Butler; Eric Neri; David Spiegel

2009-01-01

297

Obsessive–Compulsive Symptoms and the Expression of Anger  

Microsoft Academic Search

The present study investigates the association between Obsessive–Compulsive (OC) symptoms and the expression of anger in a sample of 131 undergraduates. Participants were divided into two groups based on their self-reported OC symptoms and compared on their tendency to suppress anger inwardly, express anger outwardly, and control their anger. In addition, the associations between anger and specific OC symptoms were

Stephen P. Whiteside; Jonathan S. Abramowitz

2004-01-01

298

Intractable Hiccups as Presenting Symptom of Brainstem Tumor in Children  

Microsoft Academic Search

Hiccups are an unusual presenting symptom of brainstem tumors in children. An 8-year-old boy is described who presented with hiccups 2½ years prior to any major neurological manifestation. Central nervous system etiologies of hiccups are discussed. Intractable hiccups have seldom been described as a presenting symptom of brainstem tumors. We present a patient who presented to us with this symptom

Asma Q. Fischer

1982-01-01

299

Fibromyalgia Syndrome Symptoms and Effects: A Cross-Sectional Study.  

ERIC Educational Resources Information Center

Surveyed fibromyalgia syndrome support group members about characteristics of the disease and how it affected their lives. Respondents had symptoms for many years before being diagnosed. Symptoms varied tremendously on a daily and yearly basis, so disease management was in a constant state of flux. Most symptoms significantly impacted quality of…

Prince, Alice; Bernard, Amy L.; Edsall, Patricia A.

2000-01-01

300

Anxiety and Cardiovascular Symptoms: The Modulating Role of Insomnia  

Microsoft Academic Search

Background: Anxiety and insomnia are associated with cardiovascular (CV) symptoms. We assessed whether the relation between anxiety and CV symptoms is modulated by insomnia. Methods: Independently living women (n = 1,440; mean age = 59.36 ± 6.53 years) were recruited by cluster sampling technique. We obtained data on demographic characteristics, health beliefs, access to health care, CV symptoms, sleep, stress

O. Olafiranye; G. Jean-Louis; C. Magai; F. Zizi; C. D. Brown; M. Dweck; J. S. Borer

2010-01-01

301

20 CFR 220.114 - Evaluation of symptoms, including pain.  

Code of Federal Regulations, 2010 CFR

...or has received for relief of pain or other symptoms; (vi...claimant uses or has used to relieve pain or other symptoms (e.g., lying flat on the claimant's back, standing for 15 to 20 minutes...limitations and restrictions due to pain or other symptoms. (4)...

2010-04-01

302

Postprandial Plasma Glucose Response and Gastrointestinal Symptom Severity in Patients With Diabetic Gastroparesis.  

PubMed

Gastroparesis is a well-known diabetic complication. The pathogenesis is not fully understood. However, it is important to early diagnose these patients. This study evaluated the plasma glucose response after a test meal, and gastrointestinal (GI) symptom severity in patients with clinical suspicion of diabetic gastroparesis, and assessed its usefulness to predict gastroparesis. In all, 83 subjects with insulin-treated diabetes mellitus (DM) type 1 and 2 were included; 53 subjects had gastroparesis and 30 had normal gastric emptying determined by gastric scintigraphy. GI symptom severity during the preceding 2 weeks was evaluated with a validated questionnaire. The test meal consisted of 100 g meat, 40 g pasta, 150 g carrot, and 5 g oil. The subjects ingested the meal under fasting conditions, and plasma glucose was followed during 180 minutes. Patients with gastroparesis demonstrated a blunted plasma glucose response after a test meal versus patients with normal gastric emptying (P < .005), reflected by lower maximum increase in plasma glucose response and incremental area under the curve of the plasma glucose, but a similar time to the maximum plasma glucose level. All GI symptoms were more severe in patients with gastroparesis. GI symptom severity had the best discriminative value to identify patients with gastroparesis with an area under the receiver operating curve of 0.83 (optimal cutoff: sensitivity 87%, specificity 80%). Patients with diabetic gastroparesis have a blunted postprandial plasma glucose response. Combining this information with the presence of GI symptoms can help clinicians identify diabetic patients with gastroparesis. PMID:24876417

Olausson, Eva A; Grundin, Håkan; Isaksson, Mats; Brock, Christina; Drewes, Asbjørn M; Attvall, Stig; Simrén, Magnus

2014-05-01

303

Personality and risk for postpartum depressive symptoms.  

PubMed

Postpartum depression (PPD) is a common childbirth complication, affecting 10-15 % of newly delivered mothers. This study aims to assess the association between personality factors and PPD. All pregnant women during the period September 2009 to September 2010, undergoing a routine ultrasound at Uppsala University Hospital, were invited to participate in the BASIC study, a prospective study designed to investigate maternal well-being. Depressive symptoms were assessed with the Edinburgh Postnatal Depression Scale (EPDS) while the Depression Self-Rating Scale (DSRS) was used as a diagnostic tool for major depression. Personality traits were evaluated using the Swedish Universities Scale of Personality (SSP). One thousand thirty-seven non-depressed pregnant women were included in the study. Non-depressed women reporting high levels of neuroticism in late pregnancy were at high risk of developing postpartum depressive symptoms (PPDSs) at 6 weeks and 6 months after delivery, even after adjustment for confounders (adjusted odds ratio (aOR)?=?3.4, 95 % confidence interval (CI) 1.8-6.5 and adjusted odds ratio (aOR)?=?3.9, 95 % CI 1.9-7.9). The same was true for a DSRS-based diagnosis of major depression at 6 months postpartum. Somatic trait anxiety and psychic trait anxiety were associated with increased risk for PPDS at 6 weeks (aOR?=?2.1, 95 % CI 1.2-3.5 and aOR?=?1.9, 95 % CI 1.1-3.1), while high scores of mistrust were associated with a twofold increased risk for PPDS at 6 months postpartum (aOR 1.9, 95 % CI 1.1-3.4). Non-depressed pregnant women with high neuroticism scores have an almost fourfold increased risk to develop depressive symptoms postpartum, and the association remains robust even after controlling for most known confounders. Clinically, this could be of importance for health care professionals working with pregnant and newly delivered women. PMID:25369905

Iliadis, S I; Koulouris, P; Gingnell, M; Sylvén, S M; Sundström-Poromaa, I; Ekselius, L; Papadopoulos, F C; Skalkidou, A

2014-11-01

304

Cold stress induces lower urinary tract symptoms.  

PubMed

Cold stress as a result of whole-body cooling at low environmental temperatures exacerbates lower urinary tract symptoms, such as urinary urgency, nocturia and residual urine. We established a model system using healthy conscious rats to explore the mechanisms of cold stress-induced detrusor overactivity. In this review, we summarize the basic findings shown by this model. Rats that were quickly transferred from room temperature (27 ± 2°C) to low temperature (4 ± 2°C) showed detrusor overactivity including increased basal pressure and decreased voiding interval, micturition volume, and bladder capacity. The cold stress-induced detrusor overactivity is mediated through a resiniferatoxin-sensitve C-fiber sensory nerve pathway involving ?1-adrenergic receptors. Transient receptor potential melastatin 8 channels, which are sensitive to thermal changes below 25-28°C, also play an important role in mediating the cold stress responses. Additionally, the sympathetic nervous system is associated with transient hypertension and decreases of skin surface temperature that are closely correlated with the detrusor overactivity. With this cold stress model, we showed that ?1-adrenergic receptor antagonists have the potential to treat cold stress-exacerbated lower urinary tract symptoms. In addition, we showed that traditional Japanese herbal mixtures composed of Hachimijiogan act, in part, by increasing skin temperature and reducing the number of cold sensitive transient receptor potential melastatin channels in the skin. The effects of herbal mixtures have the potential to treat and/or prevent the exacerbation of lower urinary tract symptoms by providing resistance to the cold stress responses. Our model provides new opportunities for utilizing animal disease models with altered lower urinary tract functions to explore the effects of novel therapeutic drugs. PMID:23441811

Imamura, Tetsuya; Ishizuka, Osamu; Nishizawa, Osamu

2013-07-01

305

What are the symptoms of influenza? Influenza is also known as "the flu." The most common symptoms are fever with  

E-print Network

What are the symptoms of influenza? Influenza is also known as "the flu." The most common symptoms disinfectant seven days a week. During cold and Flu season, we disinfect public touch points daily (door

Taylor, Jerry

306

[Vertigo as a symptom of psychosocial pain].  

PubMed

Vertigo in a patient with end stage lung cancer challenges the caring team. No relief can be achieved by various treatment attempts. In a retrospective analysis it turns out that the physical symptom of vertigo makes up for psychosocial pain. Causes for this reaction can be found in the patient's history and deal with solitude and loss in a wider sense. Finding out what means quality of life to an individual patient leads to general ideas about human needs. Considerations about the best place to stay for a dying person need to be merged with the options a medical system offers. PMID:20694758

Gartner, Verena; Fässler-Weibel, Peter

2010-07-01

307

Psychiatric symptoms associated with focal hand dystonia.  

PubMed

Myoclonus dystonia and idiopathic dystonia are associated with a greater frequency of obsessive compulsive disorder (OCD) and major depression. We investigated the frequency of OCD in 39 patients with primary focal hand dystonia (FHD) using a semistructured interview. OCD and subsyndromal OCD was diagnosed in 5 of 39 (12.82%) patients with FHD, whereas OCD occurs in 2.3% of the general population. Recurrent depression occurred in (7 of 39) 17.95% of patients with FHD along with a family history of depression in (16 of 39) 41.02%. Overlapping mechanisms manifesting as FHD may also predispose to OC symptoms and likely implicates a common striatal dysfunction. PMID:20737548

Voon, Valerie; Butler, Tracy R; Ekanayake, Vindhya; Gallea, Cecile; Ameli, Rezvan; Murphy, Dennis L; Hallett, Mark

2010-10-15

308

Effect of Symptoms of Adult Attention Deficit Hyperactivity Disorder on Symptoms of Post Traumatic Stress Disorder in Korean Conscripts  

PubMed Central

Objective This study is conducted to investigate the effect of symptoms of Attention Deficit and Hyperactivity Disorder (ADHD) on symptoms of Posttraumatic Stress Disorder (PTSD) among 224 conscripts during 5 weeks of military basic training. Methods Total number of subject is 224 conscripts. We evaluated past and present symptoms of ADHD with Korean-Wender Utah rating scale (K-WURS) and Korean adult attention -deficit/hyperactivity disorder scale (K-AADHDS) and stress and symptoms of PTSD with Brief Encounter Psychosocial Instrument-K (BEPSI-K), the Korean version of the Impact of Event Scale-Revised (IES-R-K) on 1 week and 5 weeks later of basic military training. Pearson correlation analysis and multivariate logistic regression analysis were performed to evaluate risk factors of PTSD using SPSS program and Path analysis also was used to find relationship between past and present ADHD and PTSD simultaneously using AMOS program. Results Present symptoms of ADHD (OR=1.145, CI=1.054-1.245, p=0.001) and Past symptoms of ADHD (OR=1.049, CI=1.005-1.095, p=0.028) were significant risk factor of PTSD symptoms on 1st week of basic military training. The symptoms of PTSD on fist week was also significant risk factor of PTSD after 5weeks of basic military training (OR=1.073, CI=1.020-1.129, p=0.006). Using path analysis, we could found confirm these relations between past and present ADHD symptoms and symptoms of PTSD. Conclusion The result suggests that past and present symptoms of ADHD are the risk factor of symptoms of PTSD on first week. And the symptoms of PTSD on first week are also risk factor of PTSD symptoms on last weeks in Korean conscripts. The symptoms of ADHD might make an important role in vulnerability of the symptoms of PTSD in Korean conscripts. PMID:22707966

Lee, Dong-Yun; Park, Chul-Soo; Kim, Bong-Jo; Cha, Bo-Seok; Lee, So-Jin; Bhang, Soo Young

2012-01-01

309

Posttraumatic Stress Disorder Symptom Structure in Injured Children: Functional Impairment and Depression Symptoms in a Confirmatory Factor Analysis  

ERIC Educational Resources Information Center

Objective: To examine the factor structure of posttraumatic stress disorder (PTSD) symptoms in children and adolescents who have experienced an acute single-incident trauma, associations between PTSD symptom clusters and functional impairment, and the specificity of PTSD symptoms in relation to depression and general distress. Method: Examined…

Kassam-Adams, Nancy; Marsac, Meghan L.; Cirilli, Carla

2010-01-01

310

Relationship between Symptoms of Anxiety and Depression in a Sample of Arab College Students Using the Hopkins Symptom Checklist 25  

Microsoft Academic Search

Background: The controversy over the relationship between symptoms of anxiety and depression is an enduring issue. Various models have been proposed to explain this relationship. We explored the following research questions. First, using exploratory factor analysis (EFA), will the symptoms that define anxiety and depression (as in the Hopkins Symptom Checklist 25, HSCL-25) appear together in 1 factor, or are

Fawziyah A. Al-Turkait; Jude U. Ohaeri; Abdul-Hamid M. El-Abbasi; Ahmed Naguy

2011-01-01

311

Posttraumatic Symptom Structure Across Age Groups.  

PubMed

The applicability of diagnostic criteria of Posttraumatic Stress Disorder to the pediatric population has been a focus of much debate (e.g., Carrion, Weems, Ray, & Reiss, 2002 ), informing changes in the Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5). The current study examined the factor structure of posttraumatic distress among adult versus pediatric samples using confirmatory factor analysis. The analysis was performed on the DSM-IV-adherent Posttraumatic Diagnostic Scale (Foa, Cashman, Jaycox, & Perry, 1997 ) and Child Posttraumatic Symptom Scale (Foa, Johnson, Feeny, & Treadwell, 2001 ). The sample included 378 adult and 204 child and adolescent victims of diverse single-event traumas. A series of models based on previous findings and DSM-IV specification were evaluated. A 4-factor model (Intrusions, Avoidance, Dysphoria, and Hyperarousal), similar to the DSM-5 model, best fit the data among adults, and a different 4-factor model (Intrusion, Avodiance, Numbing, and Hyperarousal) best fit the data among children and adolescents. Despite some similarity, the posttraumatic symptom profiles of pediatric and adult samples may differ. These differences are not fully incorporated into the DSM-5, and warrant further examination. PMID:24635582

Helpman, Liat; Rachamim, Lilach; Aderka, Idan M; Gabai-Daie, Ayala; Schindel-Allon, Inbal; Gilboa-Schechtman, Eva

2014-03-17

312

Dimensions of depressive symptoms and smoking cessation.  

PubMed

Because different psychopathologic components of depressive symptoms may have distinct etiologies, examining their differential effects on smoking cessation may elucidate mechanisms underlying the smoking-depression relationship. Negative affect (NA), somatic features (SF), low positive affect/anhedonia (PA), and interpersonal disturbance (IP) have been identified as unique dimensions of depression that can be measured using the Center for Epidemiologic Studies Depression Scale (CESD). This study examined common and unique associations between CESD subscales and baseline smoking characteristics, nicotine withdrawal, and relapse in 157 participants enrolled in a smoking cessation trial for heavy social drinkers. Each dimension was univariately associated with negative and positive reinforcement smoking motives. Only SF had unique relations with tolerance smoking motives and univariate associations with nicotine dependence severity. Only PA predicted cessation-related changes in withdrawal symptoms on quit day. Analyses predicting abstinence at 8, 16, and 26 weeks post quit date showed that NA, SF, and PA each univariately predicted relapse, ps< or =.0083. Only low PA predicted poorer outcomes incrementally to the other dimensions, even when controlling for level of nicotine dependence, smoking frequency, and history of major depression, p = .0018. Interventions targeting anhedonia and low positive affect may be useful for smokers trying to quit. PMID:18324570

Leventhal, Adam M; Ramsey, Susan E; Brown, Richard A; LaChance, Heather R; Kahler, Christopher W

2008-03-01

313

Symptom Checklist 90-Revised in neurological outpatients.  

PubMed

The Symptom Checklist 90-Revised (SCL-90-R) is an international, widely used, self-report questionnaire of multidimensional complaints with normative data for healthy control subjects and psychiatric patients. The questionnaire is also often used in neurological patients. Little is known about the amount and pattern of complaints in this group, and normative data are lacking. We therefore analyzed self-reported symptoms on the SCL-90-R of a neurological population (N = 600). Moreover, we compared the answer patterns of five subgroups: neurodegenerative disease, cerebrovascular disease, epilepsy, brain tumor, and traumatic brain injury. Neurological outpatients scored significantly higher in comparison with normative data from healthy control subjects, with most pronounced scores on Inadequacy of Thinking and Acting, Depression, and Somatization (p < .01, effect sizes 1.69, 0.83, and 0.83). No differences between the various pathologies were found. Although it is difficult to determine whether the complaints arise directly from the neurological disease or more indirectly from psychiatric disturbances accompanying the disease, simply comparing a neurological patient to normative data for healthy control subjects can lead to inappropriate classifications. Complaints of our patients should not be directly interpreted as psychopathology. A two-step procedure in which scores on the SCL-90-R are first compared to healthy control subjects and secondly to neurological patients can be helpful in the interpretation. PMID:24479727

Ruis, Carla; van den Berg, Esther; van Stralen, Haike E; Huenges Wajer, Irene M C; Biessels, Geert Jan; Kappelle, L Jaap; Postma, Albert; van Zandvoort, Martine J E

2014-01-01

314

Experience of symptoms indicative of gynaecological cancers in UK women  

PubMed Central

Background: Gynaecological cancers account for ?12% of female cancer incidence in the United Kingdom. Encouraging prompt help-seeking for potential symptoms could help improve outcomes. However, before developing help-seeking interventions, it is important to estimate the number of women with symptoms potentially indicative of a gynaecological cancer to help estimate the impact of such interventions on primary care. Methods: As part of a face-to-face, population-based survey, women aged ?16 (n=911) were shown a list of symptoms potentially indicative of a gynaecological cancer and were asked to indicate any experienced in the last 3 months. Those who reported symptoms were asked about their responses to one randomly selected index symptom. Results: Just under half (44%) of the respondents reported a symptom, with 35% reporting a frequent and/or severe symptom. Younger (P<0.001), lower socioeconomic status (P<0.01) and non-White women (P<0.05) were significantly more likely to report symptoms. Few (14%) respondents were both older (?45 years) and had a frequent and/or severe symptom. Of these women, 38% had seen a GP. Conclusion: Symptoms that potentially indicate a gynaecological cancer, even if limited to those that are frequent and/or severe, appear to be common. Consequently, encouraging prompt help-seeking may increase the burden on primary care. However, targeting those at increased risk (older women with frequent or severe symptoms) should avoid unmanageable increases in primary care consultations for gynaecological conditions. PMID:23880819

Low, E L; Simon, A E; Waller, J; Wardle, J; Menon, U

2013-01-01

315

Sensory and motor secondary symptoms as indicators of brain vulnerability  

PubMed Central

In addition to the primary symptoms that distinguish one disorder from the next, clinicians have identified, yet largely overlooked, another set of symptoms that appear across many disorders, termed secondary symptoms. In the emerging era of systems neuroscience, which highlights that many disorders share common deficits in global network features, the nonspecific nature of secondary symptoms should attract attention. Herein we provide a scholarly review of the literature on a subset of secondary symptoms––sensory and motor. We demonstrate that their pattern of appearance––across a wide range of psychopathologies, much before the full-blown disorder appears, and in healthy individuals who display a variety of negative symptoms––resembles the pattern of appearance of network abnormalities. We propose that sensory and motor secondary symptoms can be important indicators of underlying network aberrations and thus of vulnerable brain states putting individuals at risk for psychopathology following extreme circumstances. PMID:24063566

2013-01-01

316

Sex differences in responding to rectal cancer symptoms  

PubMed Central

Many people who develop cancer symptoms wait inordinate amounts of time before seeking medical attention. Studies have found that symptom appraisal time - the time that passes before the individual concludes that their symptoms could be serious - accounts for most of the total delay time across subjects. It is thus important to understand the individual characteristics associated with slow recognition of dangerous symptoms. In this study, 62 patients (38 males) recently diagnosed with rectal cancer answered questions regarding the development of symptoms as well as their decisions and behaviors prior to seeking help. One subgroup of patients - males with the lowest scores on a measure of trait anxiety - took significantly longer to recognize the seriousness of their symptoms as compared to all other patients. This finding is discussed in the context of recent studies where the interaction of sex and negative affect is related to symptom reporting and other health-related behaviors. PMID:19759846

RISTVEDT, STEPHEN L.; TRINKAUS, KATHRYN M.

2009-01-01

317

Developmental Pathways Linking Externalizing Symptoms, Internalizing Symptoms, and Academic Competence to Adolescent Substance Use  

ERIC Educational Resources Information Center

This study extends previous research investigating the developmental pathways predicting adolescent alcohol and marijuana use by examining the cascading effects of externalizing and internalizing symptoms and academic competence in the prediction of use and level of use of these substances in adolescence. Participants (N = 191) were drawn from a…

Englund, Michelle M.; Siebenbruner, Jessica

2012-01-01

318

Extrapyramidal symptoms and signs in Alzheimer's disease: Pravalence and correlation with the first symptom  

Microsoft Academic Search

Objectives: To determine the prevalence and clinical correlates of extrapyramidal signs (EPS) in outpatients with probable Alzheimer's disease (AD); to examine the appearance of EPS in association with the first symptom that led the patient or family to ask for medical help; to examine the association of the prevalence of EPS with gender, age at onset of the disease, duration

M. Tsolaki; K. Kokarida; V. Iakovidou; E. Stilopoulos; J. Meimaris; A. Kazis

2001-01-01

319

Pathological pregnancy and psychological symptoms in women.  

PubMed

Pregnancy is followed by many physiologic, organic and psychological changes and disorders, which can become more serious in pregnancy followed by complications, especially in women with pathological conditions during pregnancy. The purpose of this study was to find out and analyze the prevalence and intensity of psychological disorders in women with pathological conditions during pregnancy and compare it with conditions in pregnant women who had normal development of pregnancy. The research is approved by the Ethical committee of the Mostar University Hospital Center, and it was made in accordance with Helsinki declaration and good clinical practices. The research conducted section for pathology of pregnancy of Department for gynecology and obstetrics of the Mostar University Hospital Center. It included 82 pregnant women with disorders in pregnancy developement and control group consisted of pregnant women who had normal development of pregnancy. The research work was conducted from September 2007 to August 2008 in Mostar University Hospital Center. Pregnant women had Standard and laboratory tests, Ultrasound. CTG examinations were done for all pregnant women and additional tests for those women with complications during pregnancy. Pregnant women completed sociobiographical, obstetrical-clinical and psychological SCL 90-R questionnaire. Pregnant women with pathological pregnancy exibited significantly more psychological symptoms in comparison to pregnant women with normal pregnancy (p < 0.001 to p = 0.004). Frequency and intensity of psychical symptoms and disorders statisticly are more characteristic in pathological pregnancy (61%/40.6%). The statistical data indicate a significantly higher score of psychological disorders in those pregnant women with primary school education (p = 0.050), those who take more than 60% carbohydrates (p = 0.001), those with pathological CTG records (p < 0.001), those with pathological ultrasound results (p < 0.001 to 0.216) and those pregnant women with medium obesity and obesity (p = 0.046). Body mass index (BMI) during normal pregnancy development is lower (p = 0.002) but the levels of glucose, triglycerides, cholesterol, HDL and LDL in blood are higher Blood pressure in pregnant women with pathological pregnancy was statistically significantly higher (p < 0.001). Diagnostic criteria for the metabolic syndrome were found in 19 pregnant women with the pathological pregnancy. Statistically, in those women, a significantly higher appearance of psychological symptoms and disorders was observed in comparison to the pregnant women without metabolic syndrome (p < 0.001). The research has shown that 87.8% from all pregnant women included in this study have been hospitalized due to premature birth, hypertensive disorders, and diabetes in pregnancy, and also due to bleeding in the second and third trimester of pregnancy. PMID:23213943

Bjelanovi?, Vedran; Babi?, Dragan; Oreskovi?, Slavko; Tomi?, Vajdana; Martinac, Marko; Juras, Josip

2012-09-01

320

[Contact granuloma: symptoms, etiology, diagnosis, therapy].  

PubMed

Contact ulcer granuloma has a multifactorial etiology but vocal abuse is considered the most important etiological factor. Some other possible factors are well-known: tuberculosis, allergies, hormonal or autonomic imbalance, psychosomatic influences, reflux-esophagitis, pathological conditions of the nose, nasal accessory sinus, tonsils. Constitutional factors play also an important role. The symptoms range from mild huskiness to severe hoarseness with pain extending to the ear, dysphagia, sometimes hemoptysis and chronic cough. Failure to recognize the pathological features of this frequently overlooked lesion leads to diagnosis of larynx cancer, angiosarcoma or hemangioma. Indication for microsurgical removal is only severe dyspnea by size of mass or if the dignity is not clear, because any surgical procedure has only temporary value and does not eliminate the etiological factors. The dignity can normally be proved by stroboscope. Vocal rehabilitation and re-education are an essential appropriate means of treatment for this disease if other causative factors are excluded. PMID:1575850

Sieron, J; Johannsen, H S

1992-04-01

321

Pathology Case Study: Flu-Like Symptoms  

NSDL National Science Digital Library

This is a case study presented by the University of Pittsburgh Department of Pathology which presents a "37-year-old white female who was in excellent health until three years prior, when she developed flu-like symptoms." Visitors are given an extensive patient history along with pathologic findings, including images, and are given the opportunity to diagnose the patient. A "Final Diagnosis" section provides a discussion of the findings as well as references. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in cardiovascular pathology.

Klionsky, Bernard

322

Does disgust enhance eating disorder symptoms?  

PubMed

In the present study, the hypothesized causal relationship between disgust and eating pathology was investigated. Female undergraduates were either assigned to an experimental condition in which feelings of disgust were induced by means of a bad smelling odorant, or to a control condition in which no such disgust manipulation was carried out. Both groups completed questionnaires for measuring various eating disorder-related concepts (i.e., body esteem, restraint eating, and body change strategies). In addition, explicit and implicit preferences for high-caloric food were measured. Results demonstrated that women in the experimental condition did not report lower levels of body esteem, and neither showed higher levels of restraint eating or other body change strategies. Furthermore, they did not display a decreased explicit or implicit preference for high-caloric food. Thus, in the present study no indication for a causal relation between disgust and eating disorder symptoms in young females was found. PMID:18167331

Mayer, Birgit; Bos, Arjan E R; Muris, Peter; Huijding, Jorg; Vlielander, Martha

2008-01-01

323

[Symptoms reported by mobile cellular telephone users].  

PubMed

A survey study, using questionnaire, was conducted in 161 students and workers in a French engineering school on symptoms experienced during use of digital cellular phones. A significant increase in concentration difficulty (p < 0.05) was reported by users of 1800-MHz (DCS) cellular phones compared to 900-MHz (GSM) phone users. In users of cellular phones, women significantly (p < 0.05) complained more often of sleep disturbance than men. This sex difference for sleep complaint is not observed between women and men non-users of cellular phone. The use of both cellular phones and VDT significantly (p < 0.05) increased concentration difficulty. Digital cellular phone users also significantly (p < 0.05) more often complained of discomfort, warmth, and picking on the ear during phone conversation in relation with calling duration per day and number of calls per day. The complaint of warmth on the ear might be a signal to users for stopping the call. PMID:11367556

Santini, R; Seigne, M; Bonhomme-Faivre, L; Bouffet, S; Defrasne, E; Sage, M

2001-04-01

324

Factors influencing postconcussion and posttraumatic stress symptom reporting following military-related concurrent polytrauma and traumatic brain injury.  

PubMed

The purpose of this study was to identify factors that are predictive of, or associated with, high endorsement of postconcussion and posttraumatic stress symptoms following military-related traumatic brain injury (TBI). Participants were 1,600 U.S. service members (age: M = 27.1, SD = 7.1; 95.4% male) who had sustained a mild-to-moderate TBI and who had been evaluated by the Defense and Veterans Brain Injury Center at one of six military medical centers. Twenty-two factors were examined that included demographic, injury circumstances/severity, treatment/evaluation, and psychological/physical variables. Four factors were statistically and meaningfully associated with clinically elevated postconcussion symptoms: (i) low bodily injury severity, (ii) posttraumatic stress, (iii) depression, and (iv) military operation where wounded (p < .001, 43.2% variance). The combination of depression and posttraumatic stress symptoms accounted for the vast majority of unique variance (41.5%) and were strongly associated with, and predictive of, clinically elevated postconcussion symptoms [range: odds ratios (OR) = 4.24-7.75; relative risk (RR) = 2.28-2.51]. Five factors were statistically and meaningfully associated with clinically elevated posttraumatic stress symptoms: (i) low bodily injury severity, (ii) depression, (iii) a longer time from injury to evaluation, (iv) military operation where wounded, and (v) current auditory deficits (p < .001; 65.6% variance accounted for). Depression alone accounted for the vast majority of unique variance (60.0%) and was strongly associated with, and predictive of, clinically elevated posttraumatic stress symptoms (OR = 38.78; RR = 4.63). There was a very clear, strong, and clinically meaningful association between depression, posttraumatic stress, and postconcussion symptoms in this sample. Brain injury severity, however, was not associated with symptom reporting following TBI. PMID:24723461

Lange, Rael T; Brickell, Tracey A; Kennedy, Jan E; Bailie, Jason M; Sills, Cheryl; Asmussen, Sarah; Amador, Ricardo; Dilay, Angelica; Ivins, Brian; French, Louis M

2014-06-01

325

Symptom Cluster Analyses Based on Symptom Occurrence and Severity Ratings Among Pediatric Oncology Patients During Myelosuppressive Chemotherapy  

PubMed Central

Background Symptom cluster research is an emerging field in symptom management. The ability to identify symptom clusters that are specific to pediatric oncology patients may lead to improved understanding of symptoms’ underlying mechanisms among patients of all ages. Objective The purpose of this study, in a sample of children and adolescents with cancer who underwent a cycle of myelosuppressive chemotherapy, was to compare the number and types of symptom clusters identified using patients’ ratings of symptom occurrence and symptom severity. Interventions/Methods Children and adolescents with cancer (10 to 18 years of age; N=131) completed the Memorial Symptom Assessment Scale 10–18 on the day they started a cycle of myelosuppressive chemotherapy, using a one week recall of experiences. Symptom data based on occurrence and severity ratings were examined using Exploratory Factor Analysis (EFA). The defined measurement model suggested by the best EFA model was then examined with a latent variable analysis. Results Three clusters were identified when symptom occurrence ratings were evaluated which were classified as a chemotherapy sequelae cluster, mood disturbance cluster, and a neuropsychological discomforts cluster. Analysis of symptom severity ratings yielded similar cluster configurations. Conclusions Cluster configurations remained relatively stable between symptom occurrence and severity ratings. The evaluation of patients at a common point in the chemotherapy cycle may have contributed to these findings. Implications for Practice Additional uniformity in symptom clusters investigations is needed to allow appropriate comparisons among studies. The dissemination of symptom clusters research methodology through publication and presentation may promote uniformity in this field. PMID:21921793

Baggott, Christina; Cooper, Bruce A.; Marina, Neyssa; Matthay, Katherine K.; Miaskowski, Christine

2011-01-01

326

A prospective study of predictors of depression symptoms in police.  

PubMed

Police work is one of the most stressful occupations. Previous research has indicated that work stress and trauma exposure may place individuals at heightened risk for the development of depression symptomatology. This prospective longitudinal study was designed to examine predictors of depression symptoms in police service. Participants comprised 119 healthy police recruits from an ongoing prospective study. They completed baseline measures of depression symptoms, childhood trauma exposure, neuroticism, and self-worth during academy training. Follow-up measures of depression symptoms, PTSD symptoms, critical incident exposure, negative life events, and routine work environment stress were assessed after 12 months of police service. Hierarchical linear regression analysis was conducted to examine predictors of current levels of depression symptoms, controlling for baseline depression symptoms and current PTSD symptoms. Greater childhood trauma exposure, lower self-worth during training, and greater perceived work stress in the first year of police service predicted greater depression symptoms at 12 months. Depression symptoms at 1 year of police service were partly independent from PTSD symptoms at 12 months. Greater childhood trauma exposure and lower self-worth during training may be important variables to screen as risk factors for duty-related depression. Strategies to reduce routine work environment stress have the potential to decrease duty-related depression in law enforcement. PMID:20044144

Wang, Zhen; Inslicht, Sabra S; Metzler, Thomas J; Henn-Haase, Clare; McCaslin, Shannon E; Tong, Huiqi; Neylan, Thomas C; Marmar, Charles R

2010-02-28

327

Post-operative hyponatraemia in orthopaedic injury  

Microsoft Academic Search

Post-operative hyponatraemia can be dangerous and can go unrecognised as the presenting signs and symptoms are often confused with post-operative or post-anaesthesia sequelae. Infusion of dextrose containing fluids in the peri-operative period is a well-documented cause of this electrolyte imbalance.We conducted a retrospective study to identify the incidence of hyponatraemia following surgery for orthopaedic injury. Medical notes and fluid charts

A. A. Tambe; R. Hill; P. J. Livesley

2003-01-01

328

Rate and predictors of psychotic symptoms after Kashmir earthquake.  

PubMed

Psychotic symptoms are more common in general population than validated diagnosis of psychosis. There is evidence to suggest that these symptoms, hallucinations, paranoia, elated mood, thought insertion, are part of a spectrum of psychosis and may have association with the same risk factors that determine development of psychosis. These symptoms have an association with exposure to psychological trauma, post-traumatic stress disorder, anxiety and depression. The aim of this study was to explore the prevalence of psychotic symptoms in the population affected by a natural disaster, earthquake in this case and possible correlates of these symptoms. We conducted a cross-sectional survey of a population sample affected by the disaster, comprising of 1,291 individuals, 18 months after 2005 earthquake in Northern Pakistan and Kashmir to look at the prevalence of these symptoms and their correlates. Screening Instrument for Traumatic Stress in Earthquake Survivors and Self-Reporting Questionnaire and Psychosis Screening Questionnaire were used as tools. We examined association between the symptoms of anxiety, depression, PTSD and psychotic symptoms. We performed logistic regression analysis where hallucinations and delusions were dependent variables and demographic and trauma exposure variables were independent variables. The prevalence of psychotic symptoms ranged between 16.8 and 30.4 %. They were directly correlated with symptoms of post-traumatic stress disorder as well as concurrent symptoms of anxiety and depression. Lower level of education had a strong association in all the regression models. For hallucinations, living in a joint family had a negative association and participation in rescue, history of exposure to previous trauma and past psychiatric history had positive association. Paranoia was associated with female gender. Any psychiatric symptom was associated death of a family member, history of past psychiatric illness and living in a tent at the time of interview. Pattern of association of psychotic symptoms is consistent with prior literature and can be understood in the light of stress vulnerability model. PMID:25421792

Ayub, Muhammad; Saeed, Khalid; Kingdon, David; Naeem, Farooq

2014-11-25

329

Symptoms in Children with Convergence Insufficiency: Before and After Treatment  

PubMed Central

Purpose To investigate symptom patterns and evaluate the relationship between patient characteristics and symptom severity before and after treatment for symptomatic children with convergence insufficiency (CI). Methods In a randomized clinical trial, the Convergence Insufficiency Symptom Survey (CISS) was administered pre- and post-treatment to 221 children 9 to <18 years with symptomatic CI. Frequency of symptom type was determined at baseline, mean change in performance-related versus eye-related symptoms for treatment responders was compared, and the relationship between patient characteristics and symptom severity at baseline for the entire cohort and after treatment for those who responded to treatment, was determined. Results At baseline, the score for performance-related symptoms was greater than that for eye-related symptoms (mean response of 2.3 vs. 1.8, p<0.001) regardless age, sex, race/ethnicity, or presence of parent-reported ADHD. Symptom severity increased with age for both the overall and eye-related subscale scores (p=0.048, p=0.022, respectively). Children with parent-reported ADHD were more symptomatic (p=0.005) than those without parent-reported ADHD because of a higher performance-related score (p<0.001). A significant and equal improvement (p<0.01) for the performance-related and eye-related symptoms was found in treatment responders. Girls had significantly lower performance-related symptoms than boys (p=0.014) and African-American children reported less eye-related symptoms than White children (p=0.022). Children without parent-reported ADHD had significantly less symptoms overall and less eye-related symptoms than children with parent-reported ADHD (p=0.019, p=0.011, respectively). Conclusions Because of a high frequency of both performance- and eye-related symptoms, clinicians should perform a targeted history that addresses both types of symptoms to help identify children with symptomatic CI. Future study regarding the relationship of CI and symptoms and their potential influence on ADHD, reading performance, and attention is warranted. PMID:22922781

Barnhardt, Carmen; Cotter, Susan A.; Mitchell, G. Lynn; Scheiman, Mitchell; Kulp, Marjean T.

2012-01-01

330

Dissociative Symptoms and Mother's Marital Status in Young Adult Population.  

PubMed

Current findings suggest that mother's marital status indicating father's absence or conflicting relationship to father may be specifically related to dissociation and other stress-related symptoms.We have assessed relationships of mother's marital status, dissociative symptoms, and other psychopathological manifestations in a sample of 19 years' old young adults (N?=?364) participating in European longitudinal study (European Longitudinal Study of Parenthood and Childhood).The results show clinically significant manifestations of dissociative symptoms in young adult men whose mothers were fatherless and in women whose mothers were re-married. Other psychopathological symptoms did not reach clinically significant manifestations.The results suggest that significant factor related to high level of dissociative symptoms in men growing in fatherless families might be linked with disturbed and conflicting attachment to a father's figure and pathological dependent attachment to mother. In women dissociative symptoms likely are linked to conflicting relationship between mother and daughter associated with stepfather' presence in the family. PMID:25590849

Bob, Petr; Selesova, Petra; Raboch, Jiri; Kukla, Lubomir

2015-01-01

331

[A case of herpetic facial paralysis in which cochleovestibular symptoms outweigh facial nerve symptoms].  

PubMed

A 42-year-old man presented with sensorineural hearing loss of acute onset, tinnitus, and vertigo. Physical examination revealed slight asymmetry in facial nerve functions and spontaneous nystagmus. Magnetic resonance imaging of the internal acoustic canal showed contrast enhancement consistent with edema-inflammation, being notable and diffuse in the seventh and eighth cranial nerve complex, and minimal in the cochlea. Non-hydropic cochleovestibular syndrome was considered and the patient was treated with antiviral and corticosteroid medications. A week later, facial paralysis improved and the acute hearing loss reversed. On the twelfth day of presentation, he had no complaints other than mild imbalance on abrupt changes in movement. In this type of herpetic facial paralysis in which cochleovestibular symptoms outweigh facial nerve symptoms, it might be argued that varicella zoster virus reactivation occurs in the spiral and/or vestibular ganglion. PMID:18443402

Avci, Suat; Kansu, Leyla; Akkuzu, Babür; Ozgirgin, Nuri; Ozlüo?lu, Levent

2008-01-01

332

Insomnia symptoms, nightmares, and suicide risk: duration of sleep disturbance matters.  

PubMed

Duration of insomnia symptoms or nightmares was investigated to see if it was related to suicide risk independent of current insomnia symptoms, nightmares, anxiety symptoms, depressive symptoms, and posttraumatic symptoms. The cross-sectional study involved analyses of survey responses from undergraduate students who endorsed either insomnia symptoms (n = 660) or nightmares (n = 312). Both insomnia symptom and nightmare duration were significantly associated with suicide risk independent of current insomnia symptoms or nightmares, respectively. Relations were also significant after controlling for anxiety symptoms, depressive symptoms, and posttraumatic symptoms. Results suggest that duration of sleep disturbance is relevant when assessing suicide risk. PMID:23278677

Nadorff, Michael R; Nazem, Sarra; Fiske, Amy

2013-04-01

333

Obstetric, somatic, and demographic risk factors for postpartum depressive symptoms  

Microsoft Academic Search

Objective:To identify and test the predictive power of potential independent risk factors of postpartum depressive symptoms during pregnancy and the perinatal period.Methods:We conducted a case-control study where 132 women with postpartum depressive symptoms were selected as an index group and 264 women without depressive symptoms as a control group. Data related to sociodemographic status, medical, gynecologic, and obstetric history, pregnancy,

Ann Josefsson; Lisbeth Angelsiöö; Göran Berg; Carl-Magnus Ekström; Christina Gunnervik; Conny Nordin; Gunilla Sydsjö

2002-01-01

334

Symptom Patterns among Youth Exposed to Intimate Partner Violence  

Microsoft Academic Search

Children and adolescents exposed to intimate partner violence display a broad range of symptoms. We sought to differentiate\\u000a symptom patterns and predictors of these patterns using a person-oriented approach. Previous cluster analysis research of\\u000a exposed youth was extended to include youth PTSD symptoms and trauma history. Participants were 74 mothers who had received\\u000a a police call for domestic violence, and

Jason M. Lang; Carla Smith Stover

2008-01-01

335

Relationship Between Obsessive Beliefs and Obsessive–Compulsive Symptoms  

Microsoft Academic Search

The aim of this study was to examine the relationship between symptom presentation in obsessive–compulsive disorder (OCD) and dysfunctional beliefs hypothesized to relate to OCD. Five-hundred sixty two undergraduates completed self-report measures of OCD symptoms and OCD-related beliefs, as well as measures of social anxiety and depression. The tendency to overestimate threat significantly predicted the OCD symptom domains of washing,

David F. Tolin; Carol M. Woods; Jonathan S. Abramowitz

2003-01-01

336

Obsessive–compulsive symptoms in patients with temporal lobe epilepsy  

Microsoft Academic Search

The goals of this work were to: (1) determine the prevalence of clinically significant obsessive–compulsive (OC) symptoms in patients with temporal lobe epilepsy (TLE), (2) characterize the differences in self-reported OC symptoms in patients with TLE and a normative control group, and (3) compare the severity of OC symptoms in right and left hemisphere TLE patients. Patients with TLE (n=30)

Keren L. Isaacs; John W. Philbeck; William B. Barr; Orrin Devinsky; Kenneth Alperb

2004-01-01

337

Parent perceptions of symptom severity in Tourette's syndrome.  

PubMed

The families of 66 consecutive children with Tourette's syndrome were surveyed for their perception of symptom significance using a questionnaire. Families considered attention deficit and learning difficulties to be most significant, while motor and vocal tics were least important. When present, episodic rage was the most impairing symptom. Physicians must be aware of the significance of these comorbid symptoms for patients with Tourette's syndrome. PMID:10519722

Dooley, J M; Brna, P M; Gordon, K E

1999-11-01

338

ADHD-like symptoms and attachment in internationally adopted children  

Microsoft Academic Search

Internationally adopted children seem to be more likely to show ADHD-like symptoms than non-adopted children. The aims of this study were to explore the existence of ADHD-like symptoms and\\/or diagnosis in a sample of internationally adopted children depending on their country of origin and to describe the links that may exist between the display of these symptoms and observed narrative-based

Neus Abrines; Natalia Barcons; Diana Marre; Carme Brun; Albert Fornieles; Victoria Fumadó

2012-01-01

339

Modifiable factors associated with changes in postpartum depressive symptoms  

Microsoft Academic Search

Up to 50% of mothers report postpartum depressive symptoms yet providers do a poor job predicting and preventing their occurrence.\\u000a Our goal was to identify modifiable factors (situational triggers and buffers) associated with postpartum depressive symptoms.\\u000a Observational prospective cohort telephone study of 563 mothers interviewed at 2 weeks and 6 months postpartum. Mothers reported\\u000a on demographic factors, physical and emotional symptoms, daily

Elizabeth A. Howell; Pablo A. Mora; Marco D. DiBonaventura; Howard Leventhal

2009-01-01

340

Depressive Symptoms and Cigarette Smoking in a College Sample  

Microsoft Academic Search

Objective and Participants: The authors examined (1) the relationship between depressive symptoms and cigarette smoking in a college sample and (2) the role of smoking self-efficacy (one's perceived ability to abstain from smoking) in explaining the relationship between depressive symptoms and cigarette smoking. Methods: Predominantly first-year college students at a large public university completed a self-report inventory indexing depressive symptoms,

Brent A. Kenney; Charles J. Holahan

2008-01-01

341

Cognitive Control Moderates Relations Between Impulsivity and Bulimic Symptoms  

Microsoft Academic Search

The present study, involving 128 undergraduate participants, sought to better understand relations between trait impulsivity,\\u000a cognitive control, and bulimic symptoms. Three models were contrasted. One model posited that impulsivity and cognitive control\\u000a would be independent, non-interactive predictors of bulimic symptoms. A second model posited that cognitive control deficits\\u000a would mediate relations between impulsivity and bulimic symptoms. A third model posited

Michael D. Robinson; Elizabeth A. Pearce; Scott G. Engel; Stephen A. Wonderlich

2009-01-01

342

Af projektleder, lektor, mag.scient. Holger Lykke-Andersen og lektor, cand.scient. Karen Luise Knudsen, Geologisk Institut,  

E-print Network

udgave af profil 4 (på tværs af Holsteinsborg Dyb). Med de farvede streger antydes den fore- løbige. Den ældste og dybeste dal er nedskåret i en tertiær lagserie (markeret med gule streger). Det formodes

343

Molecular Plant Volume 1 Number 3 Pages 423445 May 2008 RESEARCH ARTICLE Activation of Defense Response Pathways by OGs  

E-print Network

, or the bacterial flagellin peptide Flg22, general elicitors of the basal defense response in plants. AlthoughMolecular Plant · Volume 1 · Number 3 · Pages 423­445 · May 2008 RESEARCH ARTICLE Activation of Defense Response Pathways by OGs and Flg22 Elicitors in Arabidopsis Seedlings Carine Denouxa,b , Roberta

Ausubel, Frederick M.

344

SQUID DETECTION OF EPR IN DILUTE CMN* R.V.Chamberlin, L.A. Moberly and O.G. Symko  

E-print Network

SQUID DETECTION OF EPR IN DILUTE CMN* R.V.Chamberlin, L.A. Moberly and O.G. Symko Dept. of Physios, University of Utah, Salt Lake City, Utah 84112, U.S.A. Abstract.- We demonstrate the applicability of SQUID-lattice relaxation times. The very high sensitivity of a SQUID magne- tometer makes it an ideal instrument for every

Boyer, Edmond

345

Factor structure of the Brief Negative Symptom Scale.  

PubMed

The current study examined the factor structure of the Brief Negative Symptom Scale (BNSS), a next-generation negative symptom rating instrument developed in response to the NIMH-sponsored Consensus Development Conference on Negative Symptoms. Participants included 146 individuals with a DSM-IV diagnosis of schizophrenia or schizoaffective disorder. Principal axis factoring indicated two distinct factors explaining 68.7% of the variance. Similar to previous findings, the factors reflected motivation and pleasure and emotional expressivity. These findings provide further support for the construct validity of the BNSS, and for the existence of these two negative symptom factors. PMID:23062750

Strauss, Gregory P; Hong, L Elliot; Gold, James M; Buchanan, Robert W; McMahon, Robert P; Keller, William R; Fischer, Bernard A; Catalano, Lauren T; Culbreth, Adam J; Carpenter, William T; Kirkpatrick, Brian

2012-12-01

346

Heterogeneous trajectories of depressive symptoms: Adolescent predictors and adult outcomes  

PubMed Central

Background Depressive symptoms display heterogeneous trajectories across adolescence and early adulthood. Identifying risk and protective factors for distinct trajectory groups, and their respective outcomes, may provide insight into the etiological underpinnings of different symptom courses and inform the targets and timing of intervention. Methods A school-based sample of 719 adolescents completed four diagnostic evaluations and up to 7 annually mailed questionnaires assessing psychiatric symptoms and psychosocial risk and protective factors. Parental history of psychiatric disorder was assessed. Growth mixture modeling (GMM) was used to identify latent depressive symptom trajectories from mid-adolescence through age 30, as well as their predictors in mid-adolescence and adult outcomes. Results A three class model consisting of high stable (32%), moderate decreasing (44%), and low decreasing (24%) depressive symptom trajectories emerged as the preferred solution. Demographic, psychosocial, and psychiatric characteristics differentiated the low and high symptom classes, and provided support for interpersonal models of depression chronicity. Members of the moderate and high symptom classes evidenced the worst psychosocial and psychiatric outcomes by age 30, with members of the high symptom class showing the greatest levels of impairment. Limitations Cross-sectional measurement and floor effects of several predictor variables may have obscured the relations between those predictors and trajectory class membership. Conclusion These findings suggest that prevention and intervention strategies may specifically target young women and those who experience poor interpersonal functioning in an effort to alter the course of depressive symptoms through early adulthood. PMID:22963892

Yaroslavsky, Ilya; Pettit, Jeremy W.; Lewinsohn, Peter M.; Seeley, John R.; Roberts, Robert E.

2012-01-01

347

Depressive Symptomatology, Rather than Neuroticism, Predicts Inflated Physical Symptom Reports  

PubMed Central

Objective To examine the roles of depressive symptomatology and neuroticism/negative affect (N/NA) on common physical symptom reporting in a sample of community residents. Methods Community-residing adults (N = 108) participated in a combined concurrent-retrospective design. Physical symptoms were assessed concurrently over 21 consecutive days followed by a retrospective assessment of the collective symptom experience for the same time period. Results Based upon evidence of differences in cognitive processing of emotion-relevant material, it was predicted and found that depressive symptomatology (at baseline) was a stronger predictor of inflated physical symptom recall than N/NA. Depressive symptomatology was also a stronger, independent predictor of concurrent physical symptoms. Notably, these results were obtained even when depressive symptoms in both the physical symptom checklist and the baseline depression assessment were eliminated. Conclusions The results suggest that the classic symptom perception hypothesis should be refined and operationalized in terms of depressive symptomatology rather than N/NA. This study demonstrates how cognitive-affective processing differences associated with depressive symptomatology can shed additional light on the psychology of symptom perception. Implications for treatment seeking, medical diagnoses, and treatment decisions are discussed. PMID:19779145

Howren, M. Bryant; Suls, Jerry; Martin, René

2009-01-01

348

Latent Class Analysis of YBOCS Symptoms in Obsessive Compulsive Disorder  

PubMed Central

Objective Obsessive-compulsive disorder (OCD) is phenomenologically heterogeneous, and findings of underlying structure classification based on symptom grouping have been ambiguous to date. Variable-centered approaches, primarily factor analysis, have been used to identify homogeneous groups of symptoms, but person-centered latent methods have seen little use. This study was designed to uncover sets of homogeneous groupings within 1611 individuals with OCD, based on symptoms. Method Latent class analysis (LCA) models using 61 obsessive-compulsive symptoms (OCS) collected from the Yale-Brown Obsessive-Compulsive Scale were fit. Relationships between latent class membership and treatment response, gender, symptom severity and comorbid tic disorders were tested for relationship to class membership. Results LCA models of best fit yielded three classes. Classes differed only in frequency of symptom endorsement. Classes with higher symptom endorsement were associated with earlier age of onset, being male, higher YBOCS symptom severity scores, and comorbid tic disorders. There were no differences in treatment response between classes. Conclusions These results provide support for the validity of a single underlying latent OCD construct, in addition to the distinct symptom factors identified previously via factor analyses. PMID:21145539

Delucchi, Kevin L.; Katerberg, Hilga; Stewart, S. Evelyn; Denys, Damiaan A.J.P.; Lochner, Christine; Stack, Denise E.; den Boer, Johan A.; van Balkom, Anton J.L.M.; Jenike, Michael A.; Stein, Dan J.; Cath, Danielle C.; Mathews, Carol A.

2010-01-01

349

Nonmotor Symptoms in a Malaysian Parkinson's Disease Population  

PubMed Central

Background. The nonmotor symptoms are important determinants of health and quality of life in Parkinson's disease but are not well recognized and addressed in clinical practice. This study was conducted to determine the prevalence of nonmotor symptoms and their impact on quality of life in patients with Parkinson's disease. Methods. This was a cross-sectional study among patients with idiopathic Parkinson's disease. Exclusion criteria were a Mini Mental State Examination score of <21/30. Prevalence of nonmotor symptoms was determined using the NMSQuest. The severity of nonmotor symptoms and the quality of life were assessed using validated disease-specific questionnaires (PDQ-39 and NMSS). Results. A total of 113 patients consisting of 60 males and 53 females were recruited. The median duration of illness was 5.0 (2.0–8.0) years. The prevalence rate of nonmotor symptoms in our cohort was 97.3%. The most common reported nonmotor symptom in our cohort was gastrointestinal (76.1%). We found that the severity of the nonmotor symptoms was associated with poorer quality of life scores (rs: 0.727, P < 0.001). Conclusions. Nonmotor symptoms were highly prevalent in our patients with Parkinson's disease and adversely affected the quality of life of our patients. In contrast to western studies, the most common nonmotor symptom is gastrointestinal. The possibility of an Asian diet playing a role in this observation requires further study. PMID:24800102

Azmin, Shahrul; Khairul Anuar, Abdul Manaf; Tan, Hui Jan; Nafisah, Wan Yahya; Raymond, Azman Ali; Hanita, Othman; Shah, Shamsul Azhar; Norlinah, Mohamed Ibrahim

2014-01-01

350

Depressive symptoms and attenuated physiological reactivity to laboratory stressors.  

PubMed

There is evidence that depressive symptoms are associated with attenuated physiological reactivity to active stressors. However, it is not known whether blunted reactivity in depressed individuals is stressor-specific. We examined cardiovascular and electrodermal reactivity in non-clinical participants with varying levels of depressive symptoms to different active and passive stressors. Depressive symptoms were inversely related to both blood pressure and skin conductance reactivity during a public speaking task and the viewing of the speech video. However, no effects were found during a cold pressor task. Together these findings suggest that depressive symptoms are related to attenuated sympathetic nervous system reactivity in response to self-relevant stressors. PMID:21679744

Schwerdtfeger, Andreas; Rosenkaimer, Ann-Kathrin

2011-07-01

351

Transition of Distinctive Symptoms of Semantic Dementia during Longitudinal Clinical Observation  

Microsoft Academic Search

Background\\/Aims: The aim of this study is to examine the clinical symptoms in a number of semantic dementia (SD) patients and to reveal the longitudinal progression and clinical course of these distinctive symptoms of SD. Methods: 19 consecutive SD patients were examined. Symptoms were classified into 23 distinct categories: behavioral symptoms, language and cognitive symptoms and symptoms concerning the impairment

Tetsuo Kashibayashi; Manabu Ikeda; Kenjiro Komori; Shunichiro Shinagawa; Hideaki Shimizu; Yasutaka Toyota; Takaaki Mori; Tomohisa Ishikawa; Ryuji Fukuhara; Shu-ichi Ueno; Satoshi Tanimukai

2010-01-01

352

[Drug reaction with eosinophilia and systemic symptoms].  

PubMed

DRESS syndrome (drug reaction eosinophilia and systemic symptoms) is a rare and serious drug toxidermia with potentially multiple organ dysfunctions. This report relates the case of a 9-year-old girl who presented a right cervical and mediastinal adenopathy with a mediastinal lump, fever, and deterioration of the general condition. The hospital assessment concluded in an abscess due to Staphylococcus aureus secreting a Panton-Valentine toxin with nonsevere pleuritis and pericarditis. The outcome was favorable with antibiotic treatment consisting of amoxicillin-acid clavulanic, amikacin, and clindamycin followed by oxacillin, rifampicin, and colchicine. On the 25th day of treatment, she presented recurrence of fever with a generalized rash, moderate hepatic cytolysis, hypereosinophilia, with the presence of activated lymphocytes that were further suggestive of visceral DRESS syndrome. A skin biopsy was performed that confirmed the diagnosis. The outcome was favorable after stopping all ongoing treatments even though none of the administered treatments were classically responsible for the syndrome. Symptomatic treatments (antihistaminic and topical steroids) were also administered. Patch tests, performed secondarily, were positive to penicillins; amoxicillin-clavulanic acid or oxacillin were then suspected of being responsible for the DRESS syndrome. Potentially serious, the DRESS syndrome should be considered together with atoxic epidermal necrolysis or Stevens-Johnson syndromes in the case of any rash appearing after drug administration, especially in the presence of face and eyelid edema. PMID:25282466

Rabenkogo, A; Vigue, M G; Jeziorski, E

2015-01-01

353

Operative management of acute pancreatitis.  

PubMed

Acute pancreatitis comprises a range of diseases. Clinical manifestations range from mild symptoms to a life-threatening or life-ending process. Operative management is focused on managing the acute complications, the long-term sequelae, or the prevention of recurrent pancreatitis. Using the least amount of intervention is the goal. However, the evolution of videoscopic and endoscopic techniques have greatly expanded the tools available. This article provides a review of the three major categories of operations: ameliorating the emergent problems associated with the inflammatory state, ameliorating chronic sequelae, and prevention of a subsequent episode. PMID:23632146

Martin, Ronald F; Hein, Amanda R

2013-06-01

354

Prostatic Fibrosis is Associated with Lower Urinary Tract Symptoms  

PubMed Central

Purpose Current therapies for male lower urinary tract symptoms secondary to prostate enlargement prevent hormonal effects on prostate growth and inhibit smooth muscle contraction to ease bladder neck and urethral pressure. However, lower urinary tract symptoms can be refractory to these therapies, suggesting that additional biological processes not addressed by them may also contribute to lower urinary tract symptoms. Aging associated fibrotic changes in tissue architecture contribute to dysfunction in multiple organ systems. Thus, we tested whether such changes potentially have a role in impaired urethral function and perhaps in male lower urinary tract symptoms. Materials and Methods Periurethral tissues were obtained from a whole prostate ex vivo and from 28 consecutive men treated with radical prostatectomy. Lower urinary tract symptoms were assessed using the American Urological Association symptom index. Prostate tissues were subjected to mechanical testing to assess rigidity and stiffness. Fixed sections of these tissues were evaluated for collagen and elastin content, and glandularity to assess fibrosis. Statistical analysis included the Student t test and calculation of Pearson correlation coefficients to compare groups. Results Periurethral prostate tissues demonstrated nonlinear viscoelastic mechanical behavior. Tissue from men with lower urinary tract symptoms was significantly stiffer (p = 0.0016) with significantly higher collagen content (p = 0.0038) and lower glandularity than that from men without lower urinary tract symptoms (American Urological Association symptom index 8 or greater vs 7 or less). Conclusions Findings show that extracellular matrix deposition and fibrosis characterize the periurethral prostate tissue of some men with lower urinary tract symptoms. They point to fibrosis as a factor contributing to lower urinary tract symptom etiology. PMID:22906651

Ma, Jinjin; Gharaee-Kermani, Mehrnaz; Kunju, Lakshmi; Hollingsworth, John M.; Adler, Jeremy; Arruda, Ellen M.; Macoska, Jill A.

2012-01-01

355

Cognitive emotion regulation strategies and neuroticism in relation to depressive symptoms following burn injury: a longitudinal study with a 2-year follow-up.  

PubMed

Sustaining burns is considered a stressful life event that has the power to elicit depressive symptoms. This study aimed to identify predictors of depressive symptoms by investigating the role of demographic variables, the number of operations (burn severity), neuroticism, and cognitive emotion regulation styles as possible influencing factors. Data from 242 patients with burns were analyzed employing latent growth modeling. The level of depressive symptoms across the 2-year interval was associated with burn severity, higher levels of neuroticism and rumination, and lower levels of positive refocusing. Notably, rumination partly mediated the effect of neuroticism on the course of depressive symptoms. Correlational analysis suggested a specific effect of burn severity on rumination. The results indicate that screening for symptoms of depression, rumination, and neuroticism in burn patients is useful. Early interventions focusing on cognitive restructuring could assist in improving the cognitive emotional adaptation process following a burn event. PMID:24126570

Van Loey, Nancy E; Oggel, Anne; Goemanne, Anne-Sofie; Braem, Leen; Vanbrabant, Leonard; Geenen, Rinie

2014-10-01

356

Emotional inertia contributes to depressive symptoms beyond perseverative thinking.  

PubMed

The autocorrelation or inertia of negative affect reflects how much negative emotions carry over from moment to moment and has been associated with increased depressive symptoms. In this study, we posed three challenges to this association by examining: (1) whether emotional inertia is relevant for depressive symptoms when assessed on a longer timescale than usual; (2) whether inertia is uniquely related to depressive symptoms after controlling for perseverative thoughts; and (3) whether inertia is related to depressive symptoms over and above the within-person association between affect and perseverative thoughts. Participants (N = 101) provided ratings of affect and perseverative thoughts for 100 days; depressive symptoms were reported before and after the study, and again after 2.5 years. Day-to-day emotional inertia was related to depressive symptoms over and above trait and state perseverative thoughts. Moreover, inertia predicted depressive symptoms when adjusting for its association with perseverative thoughts. These findings establish the relevance of emotional inertia in depressive symptoms independent of perseverative thoughts. PMID:24820350

Brose, Annette; Schmiedek, Florian; Koval, Peter; Kuppens, Peter

2015-04-01

357

Cannabis dependence and psychotic symptoms in young people  

Microsoft Academic Search

Background. The aims of this research were to use data gathered over the course of a 21 year longitudinal study to examine the linkages between cannabis dependence at ages 18 and 21 and rates of psychotic symptoms taking into account previous symptom levels and other confounding factors. Method. Data were gathered during the course of the Christchurch Health and Development

2003-01-01

358

Contact Dermatitis with Systemic Symptoms from Agave americana  

Microsoft Academic Search

Background: Twelve cases of contact dermatitis provoked by Agave americana are described, 10 with systemic signs and symptoms and 8 with abnormal laboratory results. Results: Patient history revealed a background of intentional exposure among soldiers seeking sick leave. Treatment with oral antihistamines and topical saline compresses resulted in subsidence of the systemic symptoms within 24 h of hospitalization and regression

S. Brenner; M. Landau; I. Goldberg

1998-01-01

359

Copyright 2004 John Wiley & Sons, Ltd. Stress, symptoms of depression  

E-print Network

Copyright © 2004 John Wiley & Sons, Ltd. Stress, symptoms of depression and anxiety, and cortisol for associations between stress or symptoms of depression or anxiety and changes in diurnal cortisol patterns in 91. Sloan Foundation. S t r e s s a n d H e a l t h Stress and Health 20: 53­63 (2004) Published online

Stephens, Matthew

360

The Symptoms of Autism Spectrum Disorders in Adolescence and Adulthood  

Microsoft Academic Search

This article describes the symptoms of autism spectrum disorders (ASD) manifested by 405 individuals between the ages of 10 and 53 years, all of whom had an ASD diagnosis. Data were collected using the Autism Diagnostic Interview–Revised (ADI-R) to assess the pattern of autism symptoms in adolescence and adulthood. Findings include that although virtually all sample members met the criteria

Marsha Mailick Seltzer; Marty Wyngaarden Krauss; Paul T. Shattuck; Gael Orsmond; April Swe; Catherine Lord

2003-01-01

361

Confirmatory factor analysis of eating disorder symptoms in college women  

Microsoft Academic Search

Recent studies have found that the eating disorders can best be conceptualized as multidimensional. Four factors have consistently emerged from factor analytic studies of eating disorder symptoms: dietary restraint, bulimic behaviors, neurotic personality characteristics, and body image\\/body dysphoria. Confirmatory factor analysis was utilized to determine if this four-factor structure of eating disorder symptoms would be found in a sample of

Paula J. Varnado; Donald A. Williamson; Richard Netemeyer

1995-01-01

362

Effects of Retirement and Grandchild Care on Depressive Symptoms  

ERIC Educational Resources Information Center

This study explores how grandchild care in conjunction with grandparents' retirement affects depressive symptoms, using data from the Health and Retirement Survey. The findings demonstrate that retirement moderates the influence of grandchild care obligations on well-being, measured by depressive symptoms. For retired men, freedom from grandchild…

Szinovacz, Maximiliane E.; Davey, Adam

2006-01-01

363

Gender Differences in Symptoms of Autism Spectrum Disorders in Toddlers  

ERIC Educational Resources Information Center

Gender differences in symptoms representing the triad of impairments of Autism Spectrum Disorders remain unclear. To date, the majority of research conducted on this topic has utilized samples of older children. Thus, the purpose of the current study was to utilize a sample of toddlers to investigate gender differences in symptom endorsements of…

Sipes, Megan; Matson, Johnny L.; Worley, Julie A.; Kozlowski, Alison M.

2011-01-01

364

Mindfulness-based cognitive therapy for residual depressive symptoms  

Microsoft Academic Search

Objectives. Mindfulness-based cognitive therapy (MBCT) is a new group-based intervention for prevention of relapse in recurrent depression which has not been scientifically evaluated regarding its clinical effectiveness for ameliorating residual depressive symptoms following a depressive episode. The aim of this study was to assess the efficacy of MBCT in reducing residual depressive symptoms in psychiatric outpatients with recurrent depression, and

Tara Kingston; Barbara Dooley; Anthony Bates; Elizabeth Lawlor; Kevin Malone

2007-01-01

365

BACTERIAL MENINGITIS AND SWINE FLU THE DIFFERENCES BETWEEN THE SYMPTOMS  

E-print Network

BACTERIAL MENINGITIS AND SWINE FLU THE DIFFERENCES BETWEEN THE SYMPTOMS At this time of year, flu is becoming more common and, even with swine flu, is usually not a severe disease. However, the symptoms of meningitis can superficially resemble those of flu, so beware. Below is a brief summary of how

Oxford, University of

366

Aerosolization of a sneeze What are the Symptoms of Flu?  

E-print Network

Aerosolization of a sneeze What are the Symptoms of Flu? Fever Body Aches, disinfectant wipes, antiseptic hand gel and tissue to avoid extra trips out while sick. What To Do If Flu EMPLOYEE SHOULD DEVELOP FLU SYMPTOMS Send employee home and have employee seek medical attention

Fainman, Yeshaiahu

367

Withdrawal symptoms from phenytoin, carbamazepine and sodium valproate.  

PubMed Central

A prospective, double-blind, placebo-controlled investigation of possible withdrawal symptoms from phenytoin, carbamazepine and sodium valproate is reported in patients with active epilepsy, on combination therapy. There was an increase in seizures on reduction and withdrawal of carbamazepine, but there was no convincing evidence of withdrawal symptoms from any of these drugs. PMID:3144581

Duncan, J S; Shorvon, S D; Trimble, M R

1988-01-01

368

Medically unexplained symptoms and psychological problems before and after disasters  

Microsoft Academic Search

Background: Medically unexplained symptoms (MUS) may be a major public health problem, especially after disasters. What is the course of MUS in the aftermath of a disaster? Is there a difference between self-reported symptoms and those presented to the general practitioner (GP)? Is there an association between MUS and psychological problems? Methods: Data was collected in the context of two

C. J. Yzermans; B. van den Berg

2007-01-01

369

Depressive Symptoms and Cigarette Smoking in a College Sample  

ERIC Educational Resources Information Center

Objective and Participants: The authors examined (1) the relationship between depressive symptoms and cigarette smoking in a college sample and (2) the role of smoking self-efficacy (one's perceived ability to abstain from smoking) in explaining the relationship between depressive symptoms and cigarette smoking. Methods: Predominantly first-year…

Kenney, Brent A.; Holahan, Charles J.

2008-01-01

370

Depressive Symptoms and Physical Activity in Adolescent Girls  

Microsoft Academic Search

JOHNSON, C. C., D. M. MURRAY, J. P. ELDER, J. B. JOBE, A. L. DUNN, M. KUBIK, C. VOORHEES, and K. SCHACHTER. Depressive Symptoms and Physical Activity in Adolescent Girls. Med. Sci. Sports Exerc., Vol. 40, No. 5, pp. 818-826, 2008. Purpose: To evaluate the relationship between depressive symptoms and physical activity in a geographically and ethnically diverse sample of

CAROLYN C. JOHNSON; DAVID M. MURRAY; JOHN P. ELDER; JARED B. JOBE; ANDREA L. DUNN; MARTHA KUBIK; CAROLYN VOORHEES; KENNETH SCHACHTER

2008-01-01

371

Diagnosis of frontal meningioma presenting with psychiatric symptoms  

PubMed Central

The frontal lobes of the brain are notoriously “silent”: Benign tumors such as meningiomas that compress the frontal lobes from the outside may not produce any symptoms other than progressive change of personality and intellect until they are large. We present two cases with symptoms suggestive of depressive episodes, which on further investigations showed space occupying lesions suggestive of frontal meningiomas.

Yakhmi, Saurabh; Sidhu, B. S.; Kaur, Jaswinder; Kaur, Amarjit

2015-01-01

372

Gender Role Orientation and Anxiety Symptoms among African American Adolescents  

ERIC Educational Resources Information Center

The present study evaluated gender role theory as an explanation for the observed gender differences in anxiety symptoms among adolescents. Specifically, the relation between gender, gender role orientation (i.e., masculinity and femininity), self-esteem, and anxiety symptoms was examined in a community sample of 114 African Americans aged 14 to…

Palapattu, Anuradha G.; Kingery, Julie Newman; Ginsburg, Golda S.

2006-01-01

373

Gender Differences in the Reporting of Physical and Somatoform Symptoms  

Microsoft Academic Search

Objective: Women have consistently been shown to report greater numbers of physical symptoms. Our aim in this study was to assess gender differences for specific symptoms and to assess how much of these differences were attributable to psychiatric comorbidity. Method: Data from the PRIME-MD 1000 study (1000 patients from four primary care sites evaluated with the Primary Care Evaluation of

KURT KROENKE; ROBERT L. SPITZER

374

Depressive Symptoms, Coping Strategies, and Disordered Eating among College Women  

ERIC Educational Resources Information Center

In a 2-phase study with a total of 392 participants, depressive symptoms mediated the association between disordered eating and lower problem-solving confidence and an avoidance problem-solving style. Depressive symptoms did not mediate the association between the ability to generate competent solutions to hypothetical stressful situations and…

VanBoven, Amy M.; Espelage, Dorothy L.

2006-01-01

375

Pubertal Maturation and African American Children's Internalizing and Externalizing Symptoms  

ERIC Educational Resources Information Center

The association of pubertal maturation with internalizing and externalizing symptoms was examined with a sample of 867 African-American 10-12-year-old children. Children reported their pubertal development status and timing using a self-report questionnaire, and symptoms were assessed through diagnostic interviews with the children and their…

Ge, Xiaojia; Brody, Gene H.; Conger, Rand D.; Simons, Ronald L.

2006-01-01

376

Using Semantic Dependencies to Mine Depressive Symptoms from Consultation Records  

Microsoft Academic Search

With the rapid growth of depressive disorders, many psychiatric Web sites have developed various psychiatric screening services for mental health care and crisis prevention. We propose a framework for mining depressive symptoms and their relations from consultation records. The records contain many kinds of depressive symptoms, such as depressed mood, suicide ideas, anxiety, sleep disturbances, and so on. The depressive

Chung-hsien Wu; Liang-chih Yu; Fong-lin Jang

2005-01-01

377

Psychiatric Symptoms in Adults with Down Syndrome and Alzheimer's Disease  

ERIC Educational Resources Information Center

Changes in psychiatric symptoms related to specific stages of dementia were investigated in 224 adults 45 years of age or older with Down syndrome. Findings indicate that psychiatric symptoms are a prevalent feature of dementia in the population with Down syndrome and that clinical presentation is qualitatively similar to that seen in Alzheimer's…

Urv, Tiina K.; Zigman, Warren B.; Silverman, Wayne

2010-01-01

378

Changes in Parental Depression Symptoms during Family Preservation Services  

ERIC Educational Resources Information Center

Objectives: Parental depression symptoms often change over the course of child welfare family preservation and parenting services. This raises the question of whether certain processes in family preservation services might be associated with depression symptom change. This study tests three correlational models of change among family preservation…

Chaffin, Mark; Bard, David

2011-01-01

379

The relationship between father residency and a child's ADHD symptoms  

Microsoft Academic Search

Attention deficit hyperactivity disorder (ADHD) is a commonly diagnosed neuropsychological disorder among school-aged children. The purpose of the current study was to examine the relationship between father residency status and children's symptoms of ADHD using a large, nationally representative and community-based sample. To achieve this purpose, structural equation modelling was used to examine the relationship between ADHD symptoms and father

Tracey N. Sulak; Lucy Barnard-Brak; Karen Frederick

2012-01-01

380

ANALYSIS OF RELATIONSHIPS BETWEEN SYMPTOMS AND ENVIRONMENTAL FACTORS OVER TIME  

EPA Science Inventory

Weekly respiratory symptom information was obtained on a random population of 3800 whites in Tucson. The authors asked weekly about 14 symptoms representing acute respiratory illnesses (ARI), rhinitis (Rh), and other conditions. The denominator for each week was about 80 randomly...

381

The Symptom Burden of Seriously Ill Hospitalized Patients  

Microsoft Academic Search

We studied symptom burden and associated factors in a cohort of 1582 seriously ill patients admitted at five tertiary care academic centers in the U.S. between June 1989 and June 1991 in the SUPPORT Study. Logistic regression was used to test the independent association of symptoms with demographic, psychological, chronic, and acute illness measures. Pain, dyspnea, anxiety, and depression caused

Norman A. Desbiens; Nancy Mueller-Rizner; Alfred F. Connors; Neil S. Wenger; Joanne Lynn

1999-01-01

382

Food-Related Gastrointestinal Symptoms in the Irritable Bowel Syndrome  

Microsoft Academic Search

Background\\/Aims: Postprandial symptoms are common in patients with irritable bowel syndrome (IBS). However, existing studies have come to different conclusions about the role of food in the pathophysiology of IBS. We explored the prevalence of subjective food-related gastrointestinal (GI) symptoms and its relationship to clinical characteristics and psychological factors in IBS. Methods: 330 patients with IBS and 80 healthy volunteers

Magnus Simrén; Agneta Månsson; Anna Maria Langkilde; Jan Svedlund; Hasse Abrahamsson; Ulf Bengtsson; Einar S. Björnsson

2001-01-01

383

Bronchial asthma causing symptoms suggestive of angina pectoris  

Microsoft Academic Search

Many patients undergoing pharmacological stress echocardiography for assessing symptoms suggestive of coronary artery disease are found to have a normal test. This study was performed to evaluate whether asthma symptoms simulate angina pectoris. A total 41 consecutive patients who had a negative pharmacological stress echocardiography and had been evaluated for angina pectoris were studied. Patients with previously known coronary artery

D. Kiss; W. Veegh; D. Schragel; C. Bachl; C. Stollberger; K. Sertl

2003-01-01

384

PTSD symptoms and cognitive performance in recent trauma survivors  

Microsoft Academic Search

Chronic post-traumatic stress disorder (PTSD) has been associated with cognitive impairments involving memory and attention. The association between cognitive impairment and early PTSD symptoms is unknown, yet such association may lead to poorer processing of traumatic memories and thereby contribute to subsequent PTSD. This study evaluated the relationship between PTSD symptoms and cognitive functioning within 10 days of traumatic events.

Dalia Brandes; Gershon Ben-Schachar; Assaf Gilboa; Omer Bonne; Sara Freedman; Arieh Y Shalev

2002-01-01

385

Benefits of Expressive Writing in Lowering Rumination and Depressive Symptoms  

ERIC Educational Resources Information Center

Depression-vulnerable college students (with both elevated prior depressive symptoms and low current depressive symptoms) wrote on 3 consecutive days in either an expressive writing or a control condition. As predicted, participants scoring above the median on the suppression scale of the Emotion Regulation Questionnaire (Gross & John, 2003)…

Gortner, Eva-Marie; Rude, Stephanie S.; Pennebaker, James W.

2006-01-01

386

Genetic and Environmental Effects on Vocal Symptoms and Their Intercorrelations  

ERIC Educational Resources Information Center

Purpose: Recently, Simberg et al. (2009) found genetic effects on a composite variable consisting of 6 vocal symptom items measuring dysphonia. The purpose of the present study was to determine genetic and environmental effects on the individual vocal symptoms in a population-based sample of Finnish twins. Method: The sample comprised 1,728 twins…

Nybacka, Ida; Simberg, Susanna; Santtila, Pekka; Sala, Eeva; Sandnabba, N. Kenneth

2012-01-01

387

Gender differences in the perceptions of common cold symptoms  

Microsoft Academic Search

Higher rates of reported morbidity among women are sometimes attributed to lower thresholds among women for experiencing and reporting symptoms. Gender differences in the perception of signs and symptoms of minor illness were examined on data from the MRC Common Cold Unit. Volunteers assessed the presence and severity of colds at the end of their stay in the Unit, using

Sally Macintyre

1993-01-01

388

The relationship between obsessive compulsive and posttraumatic stress symptoms  

E-print Network

The relationship between obsessive­ compulsive and posttraumatic stress symptoms in clinical patients diagnosed with PTSD, 63 patients diagnosed with another anxiety disorder, and 40 college students for by a combination of symptom overlap and depression. # 2004 Elsevier Inc. All rights reserved. Keywords: Obsessive­compulsive

Liu, Taosheng

389

Obsessive-Compulsive Spectrum Disorder Symptoms in College Students  

ERIC Educational Resources Information Center

Objective: This study investigated the occurrence of obsessive-compulsive spectrum disorders (OCSDs) and associated symptomology in college students. Participants: Participants included 358 undergraduate students. Results: Results suggest that clinically significant levels of OCSD symptoms are relatively common. Additionally, OCSD symptoms

Sulkowski, Michael L.; Mariaskin, Amy; Storch, Eric A.

2011-01-01

390

Symptoms of ADHD and Close Friendships in Adolescence  

ERIC Educational Resources Information Center

Objective: This study examined the relationship of ADHD symptoms to different aspects of close friendship quality as rated by both adolescents (target adolescent and a close friend) within a friendship dyad. Method: Participants were 41 same-sex friendship dyads who completed questionnaires about their friendship. Separate symptom dimensions of…

Glass, Kerrie; Flory, Kate; Hankin, Benjamin L.

2012-01-01

391

Structure of Obsessive-Compulsive Symptoms in Pediatric OCD  

ERIC Educational Resources Information Center

The investigation of the structure of obsessive-compulsive disorder (OCD) symptoms observed in adults is similar to those observed in children is presented. This investigation indicates the structure of OCD symptoms is the same across the entire lifespan as compared to pediatric OCD and adulthood OCD.

Mataix-Cols, David; Nakatani, Eriko; Micali, Nadia; Heyman, Isobel

2008-01-01

392

Thunderclap headache as the presenting symptom of myocardial infarction.  

PubMed

Headache as the presenting symptom of myocardial ischemia has been reported in more than 20 cases. These headaches have been described as of gradual onset, associated with exertion and with EKG changes. We present herein the first case of thunderclap headache occurring at rest as the sole symptom of an acute myocardial infarction. PMID:17501856

Broner, Susan; Lay, Christine; Newman, Lawrence; Swerdlow, Michael

2007-05-01

393

Longitudinal study of symptoms and cognitive function in chronic schizophrenia  

Microsoft Academic Search

There is conflicting evidence of a relationship between changes in symptoms and cognitive functioning in schizophrenia. This study investigated longitudinal changes in psychopathology and cognitive functioning in chronic schizophrenia utilising three different dimensional models of symptomatology. Sixty-two patients diagnosed with DSM-IV schizophrenia or schizoaffective disorder were examined on two occasions over a period of 6 months for symptom improvement, measured

Catherine Hughes; Veena Kumari; William Soni; Mrigendra Das; Brendon Binneman; Sonia Drozd; Shaun O'Neil; Vallakalil Mathew; Tonmoy Sharma

2003-01-01

394

Bladder-outlet obstruction--assessment of symptoms.  

PubMed

Assessment of symptoms plays a central role in the evaluation of men with suspected bladder-outflow obstruction (BOO) secondary to benign prostatic hyperplasia (BPH). It is on the basis of symptoms that treatment designed to relieve outflow obstruction is recommended. However, a variety of studies have suggested that a considerable proportion of men presenting with suspected outflow obstruction are not obstructed as determined by pressure-flow criteria. The relationship between many so-called "obstructive" symptoms and BOO has not yet been defined. Furthermore, all previous studies have defined BOO on the basis of urethral resistance factors, which are now regarded as outdated. Using current concepts of urethral pressure-flow relationships, we studied in detail the relationship between the "obstructive" symptoms of BPH, objective evidence of abnormal voiding and BOO. Only the symptoms of hesitancy and poor flow were found to be significantly related to BOO. The symptoms of straining to void, intermittency, terminal dribbling and feeling of incomplete bladder emptying were not specific for BOO. Objective evidence of an intermittent flow pattern and of terminal dribbling do, however, have a high specificity and positive predictive value for BOO. The assessment of men with lower-urinary-tract symptoms must include objective tests of voiding function. A better understanding of the pathophysiology of lower-urinary-tract symptoms should lead to an improved symptomatic outcome of prostatectomy. PMID:7539678

Reynard, J M; Abrams, P

1995-01-01

395

Respiratory symptoms in arable farmworkers: role of storage mites.  

PubMed Central

Storage mites (acarid mites) are related to the house dust mite but are usually found in agricultural environments. They have been shown to cause allergic symptoms in Scottish farmworkers exposed to stored hay, but whether farmworkers who grow and store grain are also at risk is unknown. One hundred and one farmworkers on 22 Essex farms with grain storage facilities (88% of the available workforce) participated in a survey of respiratory symptoms, with skin tests and determination of serum levels of IgE specific for mite species, including storage mites. Of the 101 workers, 21 reported attacks of cough, wheeze, or breathlessness after exposure to stored grain and 15 reported nasal symptoms after grain exposure. Storage mite specific IgE was found in 59% of farmworkers with work related respiratory symptoms, in 60% with work related nasal symptoms, and in only 9% of symptomless farmworkers. Work related respiratory and nasal symptoms were also significantly associated with atopy, and with positive skin test responses and serum IgE specific for Dermatophagoides pteronyssinus. Storage mites were found in grain samples from 16 farms in which grain was sampled, whereas D pteronyssinus was not found in any. The close association between serum storage mite specific IgE and occupational respiratory symptoms suggests that storage mites may be responsible for respiratory symptoms in these Essex farmworkers exposed to grain. PMID:3194876

Blainey, A D; Topping, M D; Ollier, S; Davies, R J

1988-01-01

396

Negative symptoms in schizophrenia: considerations for clinical trials  

Microsoft Academic Search

There is little agreement about the methodology of clinical trials of antipsychotic drugs in patients with negative symptoms. A literature review revealed wide variation in experimental design, rating scales and study duration. This reflects differing views as to the definition and response to treatment of negative symptoms. Some degree of standardization would improve comparability of studies and aid the development

H.-J. Möller; H. M. Praag; B. Aufdembrinke; P. Bailey; T. R. E. Barnes; J. Beck; H. Bentsen; F. X. Eich; L. Farrow; W. W. Fleischhacker; J. Gerlach; K. Grafford; B. Hentschel; A. Hertkorn; S. Heylen; Y. Lecrubier; J. P. Leonard; P. McKenna; W. Maier; V. Pedersen; A. Rappard; W. Rein; J. Ryan; M. Sloth Nielsen; R.-D. Stieglitz; G. Wegener; J. Wilson

1994-01-01

397

Disasters and Depressive Symptoms in Children: A Review  

ERIC Educational Resources Information Center

Background: Disasters are destructive, potentially traumatic events that affect millions of youth each year. Objective: The purpose of this paper was to review the literature on depressive symptoms among youth after disasters. Specifically, we examined the prevalence of depression, risk factors associated with depressive symptoms, and theories…

Lai, Betty S.; Auslander, Beth A.; Fitzpatrick, Stephanie L.; Podkowirow, Valentina

2014-01-01

398

Functional upper airways obstruction: two patients with persistent symptoms  

Microsoft Academic Search

Functional upper airways obstruction is caused by vocal cord dysfunction and classically occurs in paroxysms closely resembling acute asthmatic attacks. We present two cases in which the symptoms and signs of the vocal cord dysfunction demonstrate very little variability with time. We suggest that as part of this disorder, a syndrome of chronic unremitting symptoms may occur.

C. J. Warburton; R. McL Niven; B. G. Higgins; C. A. Pickering

1996-01-01

399

Physical Symptoms and Psychological Distress among Inhalant Users.  

ERIC Educational Resources Information Center

Among 110 Mexican-American adolescents with varying drug use histories, self-reported physical health problems were not related to inhalant use history, but blood analyses indicated a relationship between extensive inhalant use and liver problems. Psychological distress symptoms were related to inhalant use and physical symptoms. Contains 23…

Joe, George W.; And Others

1991-01-01

400

Occurrence of Cognitive and Neurological Symptoms in Norwegian Dentists  

PubMed Central

Objectives Previous investigations have presented some evidence of late cognitive effects in dental personnel exposed to metallic mercury. We wanted to examine if Norwegian dentists have an increased prevalence of symptoms consistent with neurological and/or cognitive malfunction. Methods The study group consisted of 406 dentists from central Norway and 217 controls from the general population, all under the age of 70. They had responded to a standardised postal questionnaire (Euroquest) inquiring about seven symptoms in regard to neurology, psychosomatics, memory, concentration, mood, sleep disturbances, and fatigue. A score was calculated for each symptom based on 4 to 15 single questions scored on a scale from 1 (seldom or never) to 4 (very often). Results The dentists and controls had a participation rate of 57.2% and 42.9% respectively. The dentists reported no more cognitive symptoms than the controls, with low average symptom scores from 1.16 for neurological symptoms in males to 1.73 for fatigue in females. Corresponding figures for the controls were 1.22 and 1.77. There were a total of 1.2% of the dentists and 1.8% of the controls who reported having three or more of the seven symptoms "often" or more frequently. Conclusion Norwegian dentists do not report more cognitive and neurological symptoms than controls from the general population. PMID:22953200

Svendsen, Kristin; Syversen, Tore; Aas, Oddfrid; Qvenild, Torgunn

2011-01-01

401

Sleep Deprivation, Allergy Symptoms, and Negatively Reinforced Problem Behavior.  

ERIC Educational Resources Information Center

A study of the relationship between presence or absence of sleep deprivation, allergy symptoms, and the rate and function of problem behavior in three adolescents with moderate to profound mental retardation found that problem behavior was negatively reinforced by escape from instruction, and both allergy symptoms and sleep deprivation influenced…

Kennedy, Craig H.; Meyer, Kim A.

1996-01-01

402

[Pharmacological treatment of behavioral symptoms in dementia patients].  

PubMed

Cognitive manifestations usually are the primary abnormalities in dementia. In most cases cognitive deterioration arise in association with behavioral disturbances, and may accelerate institutionalization of patients. Noncognitive symptoms are distressing for both patients and their caregivers. These symptoms are described as "behavioral and psychological symptoms of dementia--BPSD" or neuropsychiatric symptoms. BPSD occurs in all types of dementia, and often are among the most prominent symptoms in the clinical course of the disease. Some disturbances like agitation and aggression may be disruptive and life-treating for patients and surrounding people. Non-pharmacological interventions should be recommended as a first line treatment unless BPSD symptoms are severe, persistent or recurrent. Drug treatment should have a specific target symptom. Atypical antipsychotics are widely used as the first line pharmacological approach to treat BPSD. Antidepressants, anxiolytics and antiepileptic's are also used. Treatment with cholinesterase inhibitors and/or memantine may delay the onset of BPSD and reduce the severity of some symptoms. Effective and safe treatment of BPSD should significantly improves the quality of life of patients and their caregivers. PMID:25141581

Gabryelewicz, Tomasz

2014-01-01

403

Patient choice of primary care practitioner for orofacial symptoms  

Microsoft Academic Search

Objective To determine patients' preferences regarding consultation of medical or dental practitioners for various orofacial symptoms, including patients' perceptions of practitioners' training and ability to diagnose and treat these symptoms.Method Patients attending oral and maxillofacial clinics in Dumfries & Galloway, Scotland in relation to a variety of complaints were invited to complete a questionnaire.Results From a sample size of 254

G. L. F. Smith; J. M. Rodgers; R. W. Flynn; C. H. Malone; G. W. Bell

2008-01-01

404

Issues in selection of instruments to measure negative symptoms.  

PubMed

Guidance for selection of instruments for measurement of negative symptoms is rapidly evolving. As there are continuing advances in the description of negative symptoms, new instruments are under development, and new data on the performance of instruments emerge from clinical trials. The Scale for Assessment of Negative Symptoms (SANS), the Positive and Negative Syndrome Scale (PANSS), the Marder Negative Factor and the Negative Symptom Assessment-16 (NSA-16) are considered to be reliable and valid measures for negative symptom trials but differ with respect to their domain coverage, use of informants, integration of global scores, administration time and comprehensiveness of their structured interviews. In response to the 2005 NIMH-MATRICS consensus statement, work groups are field testing and refining two new measures, the Clinical Assessment Interview for Negative Symptoms (CAINS) and the Brief Negative Symptom Scale (BNSS). Both address the five currently recognized domains of negative symptoms, differentiate appetitive from consummatory aspects of anhedonia and address desire for social relationships. Thus far, both have exhibited promising psychometric properties. PMID:23899996

Daniel, David Gordon

2013-11-01

405

Assessing Secondary Control and Its Association with Youth Depression Symptoms  

ERIC Educational Resources Information Center

Extensive research has linked youth depression symptoms to low levels of perceived control, using measures that reflect "primary control" (i.e., influencing objective conditions to make them fit one's wishes). We hypothesized that depressive symptoms are also linked to low levels of "secondary control" (i.e., influencing the psychological impact…

Weisz, John R.; Francis, Sarah E.; Bearman, Sarah Kate

2010-01-01

406

Prediction of posttraumatic stress symptoms in children after Hurricane Andrew  

Microsoft Academic Search

The authors used an integrative conceptual model to examine the emergence of posttraumatic stress disorder (PTSD) symptoms in 568 elementary school-age children 3 months after Hurricane An- drew. The model included 4 primary factors: Exposure to Traumatic Events, Child Characteristics, Access to Social Support, and Children's Coping. Overall, 62% of the variance in children's self- reported PTSD symptoms was accounted

Eric M. Vernberg; Annette M. La Greca; Wendy K. Silverman; Mitchell J. Prinstein

1996-01-01

407

Development and Pilot Investigation of Behavioral Activation for Negative Symptoms  

ERIC Educational Resources Information Center

Negative symptoms cause functional impairment and impede recovery from psychosis, not least, because of limited developments in empirically validated treatments. This article details a pilot evaluation of a behavioral activation (BA) treatment with eight people presenting with psychosis and marked negative symptoms. The rationale for this…

Mairs, Hilary; Lovell, Karina; Campbell, Malcolm; Keeley, Philip

2011-01-01

408

A test of whether coping styles moderate the effect of PTSD symptoms on alcohol outcomes.  

PubMed

Coping style may partially account for the frequent co-occurrence of posttraumatic stress disorder (PTSD) and alcohol-use disorder (AUD). We hypothesized that avoidant and action-oriented coping styles would moderate the association between PTSD symptom severity and alcohol outcomes among U.S. Operation Enduring Freedom/Operation Iraqi Freedom veterans, such that PTSD symptoms would be most strongly and positively associated with negative alcohol-related consequences and drinking quantity when action-oriented coping was low and avoidant coping was high. The sample (N = 128; 85.2% male, M = 37.8 years old, 63.3% Caucasian) completed a diagnostic assessment for PTSD and AUD and self-report surveys measuring coping styles, drinking quantity, and negative alcohol-related consequences. Consistent with the main hypothesis, a 3-way interaction among PTSD symptom severity, avoidant coping, and action-oriented coping was found in the predicted direction (d = 0.47-0.55). Post hoc descriptive analyses indicated that veterans with a current diagnosis of PTSD, low action-oriented coping, and high avoidant coping had worse alcohol outcomes and were twice as likely to meet criteria for current AUD compared with veterans with fewer risk factors. Findings suggest that the combination of PTSD and maladaptive coping styles may be more important for understanding alcohol-related outcomes than the presence of any of these variables in isolation. PMID:25158641

Grosso, Justine A; Kimbrel, Nathan A; Dolan, Sara; Meyer, Eric C; Kruse, Marc I; Gulliver, Suzy B; Morissette, Sandra B

2014-08-01

409

Cyclic phosphatidic acid relieves osteoarthritis symptoms  

PubMed Central

Background Cyclic phosphatidic acid (cPA) is a naturally occurring phospholipid mediator with a unique cyclic phosphate ring at the sn-2 and sn-3 positions of its glycerol backbone. Natural cPA and its chemically stabilized cPA derivative, 2-carba-cPA (2ccPA), inhibit chronic and acute inflammation, and 2ccPA attenuates neuropathic pain. Osteoarthritis (OA) is a degenerative disease frequently associated with symptoms such as inflammation and joint pain. Because 2ccPA has obvious antinociceptive activity, we hypothesized that 2ccPA might relieve the pain caused by OA. We aimed to characterize the effects of 2ccPA on the pathogenesis of OA induced by total meniscectomy in the rabbit knee joint. Results Intra-articular injection of 2ccPA (twice a week for 42 days) significantly reduced pain and articular swelling. Histopathology showed that 2ccPA suppressed cartilage degeneration in OA. We also examined the effects of 2ccPA on the inflammatory and catabolic responses of human OA synoviocytes and chondrosarcoma SW1353 cells in vitro. 2ccPA stimulated synthesis of hyaluronic acid and suppressed production of the metalloproteinases MMP-1, -3, and -13. However, it had no effect on the production of interleukin (IL)-6, an inflammatory cytokine. The suppressive effect of 2ccPA on MMP-1 and -3 production in synoviocytes and on MMP-13 production in SW1353 cells was not mediated by the lysophosphatidic acid receptor, LPA1 receptor (LPA1R). Conclusions Our results suggest that 2ccPA significantly reduces the pain response to OA by inducing hyaluronic acid production and suppressing MMP-1, -3, and -13 production in synoviocytes and chondrocytes. PMID:25123228

2014-01-01

410

Depressive symptoms, self-esteem, HIV symptom management self-efficacy and self-compassion in people living with HIV.  

PubMed

The aims of this study were to examine differences in self-schemas between persons living with HIV/AIDS with and without depressive symptoms, and the degree to which these self-schemas predict depressive symptoms in this population. Self-schemas are beliefs about oneself and include self-esteem, HIV symptom management self-efficacy, and self-compassion. Beck's cognitive theory of depression guided the analysis of data from a sample of 1766 PLHIV from the USA and Puerto Rico. Sixty-five percent of the sample reported depressive symptoms. These symptoms were significantly (p ? 0.05), negatively correlated with age (r = -0.154), education (r = -0.106), work status (r = -0.132), income adequacy (r = -0.204, self-esteem (r = -0.617), HIV symptom self-efficacy (r = - 0.408), and self-kindness (r = - 0.284); they were significantly, positively correlated with gender (female/transgender) (r = 0.061), white or Hispanic race/ethnicity (r = 0.047) and self-judgment (r = 0.600). Fifty-one percent of the variance (F = 177.530 (df = 1524); p < 0.001) in depressive symptoms was predicted by the combination of age, education, work status, income adequacy, self-esteem, HIV symptom self-efficacy, and self-judgment. The strongest predictor of depressive symptoms was self-judgment. Results lend support to Beck's theory that those with negative self-schemas are more vulnerable to depression and suggest that clinicians should evaluate PLHIV for negative self-schemas. Tailored interventions for the treatment of depressive symptoms in PLHIV should be tested and future studies should evaluate whether alterations in negative self-schemas are the mechanism of action of these interventions and establish causality in the treatment of depressive symptoms in PLHIV. PMID:24093715

Eller, L S; Rivero-Mendez, M; Voss, J; Chen, W-T; Chaiphibalsarisdi, P; Iipinge, S; Johnson, M O; Portillo, C J; Corless, I B; Sullivan, K; Tyer-Viola, L; Kemppainen, J; Rose, C Dawson; Sefcik, E; Nokes, K; Phillips, J C; Kirksey, K; Nicholas, P K; Wantland, D; Holzemer, W L; Webel, A R; Brion, J M

2014-01-01

411

Al-Qaida-ledelsens fiendebilde : i hvilken grad er teorien om gruppers dannelse av fiendebilder nyttig som utgangspunkt for analyse og forståelse av al-Qaida-ledelsens ytringer?.  

E-print Network

??SAMMENDRAG Tittel: Al-Qaida-ledelsens fiendebilde Overordnet problemstilling: I hvilken grad er teorien om gruppers dannelse av fiendebilder nyttig som utgangspunkt for analyse og forståelse av al-Qaida-ledelsens… (more)

Evju, Anders Fredrik

2005-01-01

412

Prevalence of Acute Symptoms among Workers in Printing Factories  

PubMed Central

Objective. To identify socioeconomic situation factors and behavioral factors associated with the prevalence of acute symptoms among 150 printing workers in 16 printing factories in Southern Thailand. Materials and Methods. A cross-sectional study was conducted by interviewing 150 printing workers in 16 printing factories in Southern Thailand. Results. Acute symptoms comprised dizziness, drowsiness, eye irritation, light-headedness, rhinitis, shortness of breath, cough, chest tightness, nausea/vomiting, exacerbation of asthma, allergic skin reaction, and visual disorder. The prevalence of symptoms was consistently higher among workers in the printing process than among other workers. Smoking cigarettes and drinking alcohol were not associated with an increased prevalence of acute symptoms among these printing-factory workers. Conclusion. The significant associations were found between personal protective equipment and personal hygiene and prevalence of acute symptoms in printing workers. PMID:25386365

Decharat, Somsiri

2014-01-01

413

Reliability and validity of the Symptoms of Depression Questionnaire (SDQ).  

PubMed

Current measures for major depressive disorder focus primarily on the assessment of depressive symptoms, while often omitting other common features. However, the presence of comorbid features in the anxiety spectrum influences outcome and may effect treatment. More comprehensive measures of depression are needed that include the assessment of symptoms in the anxiety-depression spectrum. This study examines the reliability and validity of the Symptoms of Depression Questionnaire (SDQ), which assesses irritability, anger attacks, and anxiety symptoms together with the commonly considered symptoms of depression. Analysis of the factor structure of the SDQ identified 5 subscales, including one in the anxiety-depression spectrum, with adequate internal consistency and concurrent validity. The SDQ may be a valuable new tool to better characterize depression and identify and administer more targeted interventions. PMID:25275853

Pedrelli, Paola; Blais, Mark A; Alpert, Jonathan E; Shelton, Richard C; Walker, Rosemary S W; Fava, Maurizio

2014-12-01

414

Unique contributions of metacognition and cognition to depressive symptoms.  

PubMed

ABSTRACT This study attempts to examine the unique contributions of "cognitions" or "metacognitions" to depressive symptoms while controlling for their intercorrelations and comorbid anxiety. Two-hundred-and-fifty-one university students participated in the study. Two complementary hierarchical multiple regression analyses were performed, in which symptoms of depression were regressed on the dysfunctional attitudes (DAS-24 subscales) and metacognition scales (Negative Beliefs about Rumination Scale [NBRS] and Positive Beliefs about Rumination Scale [PBRS]). Results showed that both NBRS and PBRS individually explained a significant amount of variance in depressive symptoms above and beyond dysfunctional schemata while controlling for anxiety. Although dysfunctional attitudes as a set significantly predicted depressive symptoms after anxiety and metacognitions were controlled for, they were weaker than metacognitive variables and none of the DAS-24 subscales contributed individually. Metacognitive beliefs about ruminations appeared to contribute more to depressive symptoms than dysfunctional beliefs in the "cognitive" domain. PMID:25539184

Yilmaz, Adviye Esin; Gençöz, Tülin; Wells, Adrian

2015-01-01

415

Discrimination, Mastery, and Depressive Symptoms Among African American Men  

PubMed Central

Purpose This study examines the influence of discrimination and mastery on depressive symptoms for African American men at young (18–34), middle (35–54), and late (55+) adulthood. Method Analyses are based on responses from 1,271 African American men from the National Survey of American Life (NSAL). Results Discrimination was significantly related to depressive symptoms for men ages 35 to 54 and mastery was found to be protective against depressive symptoms for all men. Compared to African American men in the young and late adult groups, discrimination remained a statistically significant predictor of depressive symptoms for men in the middle group once mastery was included. Implications Findings demonstrate the distinct differences in the influence of discrimination on depressive symptoms among adult African American males and the need for future research that explores the correlates of mental health across age groups. Implications for social work research and practice with African American men are discussed. PMID:24436576

Watkins, Daphne C.; Hudson, Darrell L.; Caldwell, Cleopatra Howard; Siefert, Kristine; Jackson, James S.

2013-01-01

416

Respiratory symptoms and airflow limitation in asphalt workers  

PubMed Central

Aims: To assess the occurrence of respiratory symptoms and signs of airflow limitations in a group of asphalt workers. Methods: All 64 asphalt workers and a reference group of 195 outdoor construction workers from the same company participated in a cross-sectional study. Spirometric tests and a questionnaire on respiratory symptoms and smoking habits were administered. Respiratory symptoms and lung function were adjusted for age and smoking. Results: The FEV1/FVC% ratio was significantly lower in the asphalt workers than in the referents. Symptoms of eye irritation, chest tightness, shortness of breath on exertion, chest wheezing, physician diagnosed asthma, and chronic obstructive pulmonary disease (COPD) were all significantly more prevalent among the asphalt workers. Conclusion: In asphalt workers there is an increased risk of respiratory symptoms, lung function decline, and COPD compared to other construction workers. PMID:15031397

Randem, B; Ulvestad, B; Burstyn, I; Kongerud, J

2004-01-01

417

Medically unexplained physical symptoms in medical practice: a psychiatric perspective.  

PubMed Central

Clusters of medically unexplained physical symptoms have been referred to in the literature by many different labels, including somatization, symptom-based conditions, and functional somatic syndromes, among many others. The traditional medical perspective has been to classify and study these symptoms and functional syndromes separately. In psychiatry, current taxonomies (Diagnostic and Statistical Manual of Mental Disorder, 4th edition, and The International Statistical Classification of Diseases and Related Health Problems, 10th revision) classify these syndromes together under the rubric of somatoform disorders. In this article we approach medically unexplained physical symptoms from a psychiatric perspective and discuss the common features that unite multiple unexplained symptoms or functional somatic syndromes as a class. Included in this article is a discussion of nosological issues, clinical assessment, how these syndromes are viewed within the various medical specialties, and clinical management and treatment. PMID:12194898

Escobar, Javier I; Hoyos-Nervi, Constanza; Gara, Michael

2002-01-01

418

A Novel Ultrasound-Based Carotid Plaque Risk Index Associated with the Presence of Cerebrovascular Symptoms.  

PubMed

Purpose: The purpose of this study was to determine the efficacy of a novel ultrasound-based carotid plaque risk index (CPRI) in predicting the presence of cerebrovascular symptoms in patients with carotid artery stenosis. Materials and Methods: This was a cross-sectional, observational study involving 56 patients (mean age 76.6 years, 62.5?% male). Plaque grayscale median (GSM) and surface irregularity indices (SII) were measured in 82 stenosed carotid arteries (range 10?-?95?%) and combined with the degree of stenosis (DOS) in the form of (DOS*SII)/(1?+?GSM). A reduced index DOS/(1?+?GSM) not incorporating plaque surface irregularities was also investigated. Receiver operating characteristic curves (ROC) were used to study the diagnostic efficacy of CPRI, comparing against DOS and an equivalent risk index constructed using a conventional logistic regression based method with model parameters optimized to the dataset (CPRIlogistic). Results: There were 42 stenosed carotid arteries with cerebrovascular symptoms, and 40 without symptoms. The presence of symptoms significantly correlated with DOS, GSM and SII (p?symptoms than the degree of stenosis and could be valuable in studies and clinical trials aimed at identifying vulnerable carotid artery stenoses. PMID:25389913

Kanber, B; Hartshorne, T C; Horsfield, M A; Naylor, A R; Robinson, T G; Ramnarine, K V

2014-11-12

419

Sleep Duration and Depressive Symptoms: A Gene-Environment Interaction  

PubMed Central

Objective: We used quantitative genetic models to assess whether sleep duration modifies genetic and environmental influences on depressive symptoms. Method: Participants were 1,788 adult twins from 894 same-sex twin pairs (192 male and 412 female monozygotic [MZ] pairs, and 81 male and 209 female dizygotic [DZ] pairs] from the University of Washington Twin Registry. Participants self-reported habitual sleep duration and depressive symptoms. Data were analyzed using quantitative genetic interaction models, which allowed the magnitude of additive genetic, shared environmental, and non-shared environmental influences on depressive symptoms to vary with sleep duration. Results: Within MZ twin pairs, the twin who reported longer sleep duration reported fewer depressive symptoms (ec = -0.17, SE = 0.06, P < 0.05). There was a significant gene × sleep duration interaction effect on depressive symptoms (a'c = 0.23, SE = 0.08, P < 0.05), with the interaction occurring on genetic influences that are common to both sleep duration and depressive symptoms. Among individuals with sleep duration within the normal range (7-8.9 h/night), the total heritability (h2) of depressive symptoms was approximately 27%. However, among individuals with sleep duration within the low (< 7 h/night) or high (? 9 h/night) range, increased genetic influence on depressive symptoms was observed, particularly at sleep duration extremes (5 h/night: h2 = 53%; 10 h/night: h2 = 49%). Conclusion: Genetic contributions to depressive symptoms increase at both short and long sleep durations. Citation: Watson NF; Harden KP; Buchwald D; Vitiello MV; Pack AI; Stachan E; Goldberg J. Sleep duration and depressive symptoms: a gene-environment interaction. SLEEP 2014;37(2):351-358. PMID:24497663

Watson, Nathaniel F.; Harden, Kathryn Paige; Buchwald, Dedra; Vitiello, Michael V.; Pack, Allan I.; Strachan, Eric; Goldberg, Jack

2014-01-01

420

Effect of prucalopride on symptoms of chronic constipation  

PubMed Central

Background Prucalopride is a 5-HT4 receptor agonist with gastrointestinal prokinetic activities. This integrated analysis of data from three 12-week, double-blind trials evaluated the effect of prucalopride 2 mg q.d. on common constipation symptoms in women in whom laxatives had failed to provide adequate relief. The effect of prucalopride on bowel function was outside the scope of the analysis and has been described elsewhere. Methods Women with self-reported inadequate relief from laxatives and included in the prucalopride 2 mg or placebo arm of the trials were selected for analysis. Symptom severity was determined with the Patient Assessment of Constipation Symptoms (PAC–SYM) questionnaire. Observed changes from baseline in individual item scores were also evaluated by calculating Cohen's D effect sizes using baseline standard deviation (SD) (>0.2–0.5, >0.5–0.8 and >0.8 for small, moderate and large effects, respectively). Key Results Data were analyzed for 936 women. The proportion of women with a PAC-SYM severity score >2 at baseline was 50.0% for abdominal symptoms, 71.4% for stool symptoms, and 15.5% for rectal symptoms. Excluding the women without presence of a symptom at baseline from the effect size calculations showed that prucalopride 2 mg had a large effect (>0.8) on all PAC-SYM items, including abdominal pain, abdominal discomfort, bloating, straining, and painful bowel movements. For abdominal symptoms and stool symptoms, effect sizes with prucalopride 2 mg were 1.3–2.3 times larger than those with placebo. Conclusions & Inferences Prucalopride 2 mg q.d. for 12 weeks alleviates common constipation symptoms in women in whom laxatives had failed to provide adequate relief. PMID:24106924

Tack, J; Stanghellini, V; Dubois, D; Joseph, A; Vandeplassche, L; Kerstens, R

2013-01-01

421

Trajectories of Children's Internalizing Symptoms: The Role of Maternal Internalizing Symptoms, Respiratory Sinus Arrhythmia and Child Sex  

ERIC Educational Resources Information Center

Background: We assessed trajectories of children's internalizing symptoms as predicted by interactions among maternal internalizing symptoms, respiratory sinus arrhythmia (RSA) and child sex. Method: An ethnically and socioeconomically diverse sample of children (n = 251) participated during three study waves. Children's mean ages were 8.23 years…

Wetter, Emily K.; El-Sheikh, Mona

2012-01-01

422

The Developmental Association between Eating Disorders Symptoms and Symptoms of Depression and Anxiety in Juvenile Twin Girls  

ERIC Educational Resources Information Center

Objective: We investigated the role of genetic and environmental factors in the developmental association among symptoms of eating disorders, depression, and anxiety syndromes in 8-13-year-old and 14-17-year-old twin girls. Methods: Multivariate genetic models were fitted to child-reported longitudinal symptom data gathered from clinical interview…

Silberg, Judy L.; Bulik, Cynthia M.

2005-01-01

423

Item Response Theory Analyses of Adult Self-Ratings of the ADHD Symptoms in the Current Symptoms Scale  

ERIC Educational Resources Information Center

The graded response model, which is based on item response theory, was used to evaluate the psychometric properties of adult self-ratings (N = 852) of the attention deficit/hyperactivity disorder inattention, hyperactivity, and impulsivity symptoms presented in the Current Symptoms Scale. This scale has four ordered response categories. The…

Gomez, Rapson

2011-01-01

424

A new patient weighted symptom score system (DAN-PSS-1). Clinical assessment of indications and outcomes of transurethral prostatectomy for uncomplicated benign prostatic hyperplasia.  

PubMed

A patient weighted symptom score system, the Danish Prostatic Symptom Score (DAN-PSS-1), including a disease specific self administered quality of life questionnaire, is presented. The model was evaluated pre- and postoperatively in 29 patients apparently suffering from uncomplicated benign prostatic hyperplasia. The score system is based on the severity of 12 symptoms related to bladder storage and voiding function, and three questions related to sexual function (symptom score). For each of these parameters the patient must also evaluate its influence on his daily life (bother score). In the 29 patients with uncomplicated benign prostatic hyperplasia (BPH) bother scores exceeded symptom scores for the irritative symptoms but not for the obstructive symptoms, and surprisingly the symptom score was less improved than the bother score 6 months after transurethral resection of the prostate (TUR-P). Furthermore the postvoiding dribble was worsened after the operation. We find that this model, DAN-PSS-1, assists in creating a solid base for the indication for and the evaluation of treatment of uncomplicated BPH. PMID:7512748

Meyhoff, H H; Hald, T; Nordling, J; Andersen, J T; Bilde, T; Walter, S

1993-01-01

425

Reducing Incapacitating Symptoms during Space Flight: is Postural Deficiency Syndrome an Applicable Model?  

PubMed Central

Severe and prolonged unmitigated SAS and SMS related symptoms have been thoroughly described in Astronauts during adaptation periods for orbital flight and post orbital flight. It has recently been shown that there is a strong correlation between these symptoms most often suffered by astronauts to that of the symptoms of patients suffering from Postural Deficiency Syndrome (PDS) on Earth that have been successfully assessed, diagnosed and treated. International peer-reviewed literature identifies PDS as a trauma induced medical condition which originates from central neural dysregulation of sensory-motor and cognitive controls; these dysfunctions can be accurately identified, measured, and monitored via a specific ocular-vestibular-postural monitoring system along with relevant clinical data. This higher level of understanding is necessary in order to reach the next stage of success for humans living and working in Space. Central sensory-motor and cognitive controls dysfunction underlie symptoms that can adversely impact and reflect alteration of eye-hand coordination, fine tuned dexterity, body positioning in space, space projection and trajectory control, perception of environment/obstacles, orientation in space and time, sensory motor and cognitive aspects of decision making, sensory-motor/cognitive error proneness. All of these factors are necessary for Astronaut's mission capabilities, while both carrying out operations in Space and performing the tasks required during and after re-entry. The objective of this paper is to elucidate how PDS related medical conditions are currently assessed, identified and monitored, and how these methodologies and technologies translate into a potential for better understanding of astronauts' potential incapacitation during space flight operations. PMID:19048092

Souvestre, P A; Landrock, C K; Blaber, A P

2008-01-01

426

Endometriosis - A Chameleon: Patients' Perception of Clinical Symptoms, Treatment Strategies and Their Impact on Symptoms.  

PubMed

Introduction: Endometriosis is a chronic disease with differing clinical presentations. Treatment strategies depend mainly on clinical presentation and patient lifestyle. In women newly diagnosed with endometriosis, it is often difficult to understand the pathophysiologic origin, the potential individual impairment due to disease and the different treatment options. Compliance with the selected treatment is therefore often not optimal. Material and Methods: In a descriptive study, data of 51 women with endometriosis (mean age 36.2?years ±?11.3) were analyzed according to the predominant clinical presentation: asymptomatic disease, disease with typical symptoms, ovarian cysts or infertility. Results: More than 50?% of patients ascribed a therapeutic benefit to surgical intervention or endocrine treatment, especially women in the subgroup with dysmenorrhea who received combined treatment. It should be noted that in the group of women facing infertility, more than half stated that they could not decide on the value of diagnostic and therapeutic reproductive medicine. Nevertheless, more than half of the women in this group became pregnant within two years after the initial diagnosis. Discussion: When deciding on the best treatment strategy for endometriosis, it is important to take account of potential pain and infertility. Women's perception of endometriosis will vary depending on their symptoms, the time of diagnosis and their lifestyle. Offering continuous information on clinical aspects and manifestations of the disease may improve treatment outcomes. Personalized counseling is an essential part of the clinical management of the disease. PMID:25364034

Wimberger, P; Grübling, N; Riehn, A; Furch, M; Klengel, J; Goeckenjan, M

2014-10-01

427

Musculoskeletal symptoms due to technical preconditions in long cycle time work in an automobile assembly plant: a study of prevalence and relation to psychosocial factors and physical exposure  

Microsoft Academic Search

The aim was to evaluate the prevailing ergonomic conditions in a parallelized flow, long cycle time, assembly system. The evaluation focused on physical exposure, psychosocial factors and work-related musculoskeletal symptoms. A random sample of 67 assembly operators was included in a cross-sectional study mainly based on questionnaires. Hand\\/wrist symptoms were common and related to work exposure with hand-held powered tools.

Tomas Engström; Jan Johansson Hanse; Roland Kadefors

1999-01-01

428

The Effect of Wheat Germ Extract on Premenstrual Syndrome Symptoms  

PubMed Central

Pre-menstrual syndrome is one of the most common disorders in women and impairs work and social relationships. Several treatment modalities have been proposed including herbal medicines. Considering the properties of wheat germ, this study aimed to determine the effects of wheat germ extract on the symptoms of premenstrual syndrome. This triple blind clinical trial was conducted on 84 women working in hospitals affiliated to Hamadan University of Medical Sciences. Subjects completed daily symptom record form for two consecutive months. After definitive diagnosis of premenstrual syndrome, they were randomly divided into two groups of 50 people. Then, for two consecutive months, 400 mg capsules of wheat germ extract or placebo were used three times a day, from day 16 until day 5 of the next menstrual cycle. Wheat germ significantly reduced physical symptoms (63.56%), psychological symptoms (66.30%), and the general score (64.99%). Although the severity of symptoms decreased in both groups, this reduction was more significant in the wheat germ extract group (p < 0.001). On the other hand, physical symptoms decreased only in the wheat germ extract (p < 0.001) and there was no statistically significant difference in the placebo group. No complications were observed in any of the groups. It seems that using wheat germ extract reduces general, psychological and physical symptoms. PMID:25561922

Ataollahi, Maryam; Akbari, Sedigheh Amir Ali; Mojab, Faraz; Alavi Majd, Hamid

2015-01-01

429

First Rank Symptoms and Neurological Soft Signs in Schizophrenia  

PubMed Central

The aim of the study was to compare the neurological soft signs (NSS) in schizophrenia patients with and without first rank symptoms (FRS), their first degree relatives (FDR), and normal controls. The study was conducted on 60 schizophrenia patients diagnosed according to ICD 10 DCR and categorized into groups with and without FRS using Schedules for Clinical Assessment in Neuropsychiatry, 30 FDRs of the study sample, and 30 normal controls matched for age, education, and handedness. All the subjects gave written informed consent. Scale for the Assessment of Positive Symptoms and Scale for the Assessment of Negative Symptoms were applied to have a comprehensive assessment of the symptoms. NSS were assessed using Extended Standard Neurological Assessment Instrument. The correlations between NSS and clinical symptoms were relatively modest but significant. There was a weak relation between NSS and positive symptom severity. The FDR of schizophrenia patients had significantly lower NSS scores than schizophrenia patients, but only FDR of schizophrenia patients without FRS had significantly higher scores than normal controls. Our results indicate that NSS are more prominent in schizophrenia patients with negative symptoms and support the theory of NSS being a trait marker of schizophrenia particularly in those without FRS. PMID:24701561

Hembram, Mahesh; Simlai, Jayati; Chaudhury, Suprakash; Biswas, Parthasarathi

2014-01-01

430

First rank symptoms and neurological soft signs in schizophrenia.  

PubMed

The aim of the study was to compare the neurological soft signs (NSS) in schizophrenia patients with and without first rank symptoms (FRS), their first degree relatives (FDR), and normal controls. The study was conducted on 60 schizophrenia patients diagnosed according to ICD 10 DCR and categorized into groups with and without FRS using Schedules for Clinical Assessment in Neuropsychiatry, 30 FDRs of the study sample, and 30 normal controls matched for age, education, and handedness. All the subjects gave written informed consent. Scale for the Assessment of Positive Symptoms and Scale for the Assessment of Negative Symptoms were applied to have a comprehensive assessment of the symptoms. NSS were assessed using Extended Standard Neurological Assessment Instrument. The correlations between NSS and clinical symptoms were relatively modest but significant. There was a weak relation between NSS and positive symptom severity. The FDR of schizophrenia patients had significantly lower NSS scores than schizophrenia patients, but only FDR of schizophrenia patients without FRS had significantly higher scores than normal controls. Our results indicate that NSS are more prominent in schizophrenia patients with negative symptoms and support the theory of NSS being a trait marker of schizophrenia particularly in those without FRS. PMID:24701561

Hembram, Mahesh; Simlai, Jayati; Chaudhury, Suprakash; Biswas, Parthasarathi

2014-01-01

431

Psychiatric symptoms of noradrenergic dysfunction: a pathophysiological view.  

PubMed

What psychiatric symptoms are caused by central noradrenergic dysfunction? The hypothesis considered in this review is that noradrenergic dysfunction causes the abnormalities in arousal level observed in functional psychoses. In this review, the psychiatric symptoms of noradrenergic dysfunction were inferred pathophysiologically from the neuroscience literature. This inference was examined based on the literature on the biology of psychiatric disorders and psychotropics. Additionally, hypotheses were generated as to the cause of the noradrenergic dysfunction. The central noradrenaline system, like the peripheral system, mediates the alarm reaction during stress. Overactivity of the system increases the arousal level and amplifies the emotional reaction to stress, which could manifest as a cluster of symptoms, such as insomnia, anxiety, irritability, emotional instability and exaggerated fear or aggressiveness (hyperarousal symptoms). Underactivity of the system lowers the arousal level and attenuates the alarm reaction, which could result in hypersomnia and insensitivity to stress (hypoarousal symptoms). Clinical data support the hypothesis that, in functional psychoses, the noradrenergic dysfunction is in fact associated with the arousal symptoms described above. The anti-noradrenergic action of anxiolytics and antipsychotics can explain their sedative effects on the hyperarousal symptoms of these disorders. The results of animal experiments suggest that excessive stress can be a cause of long-term noradrenergic dysfunction. PMID:24372896

Yamamoto, Ken-ichi; Shinba, Toshikazu; Yoshii, Mitsunobu

2014-01-01

432

Disturbances in attachment: inhibited and disinhibited symptoms in foster children  

PubMed Central

Background Previous DSM-versions recognized an inhibited and a disinhibited subtype of the Reactive Attachment Disorder (RAD). The current DSM-5 distinguishes two different disorders, instead of two subtypes of RAD. This study examined whether a split-up of the subtypes is valid. Method In 126 foster children, attachment disorder symptoms were assessed with the Disturbances of Attachment Interview. Forms of pathogenic care were identified based on dossier analyses. Associations between symptoms of attachment disorder with internalizing and externalizing problems (Child Behavior Checklist and Teacher Report Form) were examined. Results Omnibus tests showed no significant association between type of symptoms and type of pathogenic care. Exploratory analyses did reveal an univariate association between disinhibited symptoms and history of physical abuse. Disinhibited symptoms were associated with more internalizing and externalizing problems (d’s?symptoms lack a correlation, disinhibited symptoms seem to have an externalizing and internalizing correlation. Trial registration NTR1747 PMID:25057289

2014-01-01

433

Depressive symptoms in postmenopausal women: results from the MEDIS Study.  

PubMed

Data regarding the factors associated with depressive symptoms are limited, especially in postmenopausal women. The aim of this study was to investigate to what extent depressive symptoms were present in postmenopausal women, to explore characteristics associated with depressive symptoms and to determine if time since menopause was independently associated with depressive symptoms. Data collected within the Mediterranean Islands (MEDIS) Study, a health and nutrition survey of elderly people living on Mediterranean islands was used. A total of 851 postmenopausal women living in various Greek islands, Cyprus, and Malta participated in the study. Depressive symptoms were evaluated using the Geriatric Depression Scale (GDS). Age-adjusted logistic regression analysis showed that a year's increase in the time since menopause increased the likelihood of postmenopausal women having severe depressive symptoms by 3% (odds ratio [OR] per 1 year = 1.03, 95% CI 1.001-1.05). This positive association was also evident when other potential confounding factors (i.e, living conditions, financial status, physical activity, adherence to the Mediterranean diet, smoking habits, and several clinical conditions) were also taken into account in multivariable analyses. Primary health care practitioners and public health care authorities could use the findings of this study to identify depressive symptoms early in postmenopausal women. PMID:24791809

Tsiligianni, Ioanna G; Tyrovolas, Stefanos; Bountziouka, Vassiliki; Zeimbekis, Akis; Gotsis, Efthimios; Metallinos, George; Tyrovola, Dimitra; Polychronopoulos, Evangelos; Lionis, Christos; Panagiotakos, Demosthenes

2014-01-01

434

Changes in ADHD symptom endorsement: preschool to school age.  

PubMed

To investigate endorsement patterns among the 18 DSM-IV symptoms of ADHD in a longitudinal sample of children with and without ADHD (n?=?144), as assessed at ages 4-5, 5-6, and 6-7 years. Symptom endorsements and diagnoses were determined at all time-points via K-SADS-PL interview administered to parents and supplemented by teacher questionnaires and clinician observations. Changes in endorsement patterns over time for each of the 18 DSM-IV symptoms were ascertained. Several symptoms, particularly those of inattention, were infrequently endorsed and of apparently limited diagnostic utility at ages 4-5; hyperactive/impulsive symptoms were more frequently endorsed among young children with ADHD than were inattentive symptoms. However, by ages 6-7, inattention items were somewhat superior at discriminating ADHD from Non-ADHD children. Several DSM-IV and now DSM-V symptoms provide limited diagnostic differentiation prior to school-age, particularly those most commonly observed in the context of formal schooling. Consideration should be made in future iterations of the DSM that account for such developmental and contextual differences. PMID:24343794

Curchack-Lichtin, Jocelyn T; Chacko, Anil; Halperin, Jeffrey M

2014-08-01

435

Extravehicular Mobility Unit Training Suit Symptom Study Report  

NASA Technical Reports Server (NTRS)

The purpose of this study was to characterize the symptoms and injuries experienced by NASA astronauts during extravehicular activity (space walk) spacesuit training at the Neutral Buoyancy Laboratory at Ellington Field, Houston, Texas. We identified the frequency and incidence rates of symptoms by each general body location and characterized mechanisms of injury and effective countermeasures. Based on these findings a comprehensive list of recommendations was made to improve training, test preparation, and current spacesuit components, and to design the next -generation spacesuit. At completion of each test event a comprehensive questionnaire was produced that documented suit symptom comments, identified mechanisms of injury, and recommended countermeasures. As we completed our study we found that most extravehicular mobility unit suit symptoms were mild, self-limited, and controlled by available countermeasures. Some symptoms represented the potential for significant injury with short- and long-term consequences regarding astronaut health and interference with mission objectives. The location of symptoms and injuries that were most clinically significant was in the hands, shoulders, and feet. Correction of suit symptoms issues will require a multidisciplinary approach to improve prevention, early medical intervention, astronaut training, test planning, and suit engineering.

Strauss, Samuel

2004-01-01

436

Operating Systems  

NSDL National Science Digital Library

Rashid Bin Muhammad at Kent State University presents his page of lectures notes and other instructional materials on operating systems. The site is divided into a number of topics about operating systems: history, structure, process, threads, Solaris-2, CPU / process scheduling, schedule algorithm, interprocess communication, deadlock, important UNIX commands, and references. The site is then followed by links to outside resources to help supplement the material presented here. This is a great resource for computer science instructors teaching students about operating systems.

Bin Muhammad, Rashid

2009-06-24

437

Urinary Symptoms and Risk of Falls in Older Men  

PubMed Central

OBJECTIVE To evaluate the association of urinary symptoms with risk of falls in community-dwelling elderly men. PATIENTS AND METHODS We evaluated 5872 participants in MrOS, a prospective cohort study of risk factors for falls and osteoporotic fractures among community-dwelling men aged 65 years and older. We used Poisson regression models with a robust variance estimator to evaluate the association of urinary symptoms at study entry with falls occurring during 1 year of follow-up. We considered age, history of falls, history of dizziness, multiple physical performance measures, body size, and medication use as potential confounders. RESULTS At baseline, 3188 (54%) reported mild, 2301 (39%) moderate, and 383 (7%) severe symptoms. Compared to men with mild symptoms, the adjusted 1-year cumulative incidence of falls was significantly higher among men with moderate or severe symptoms. Risk of at least 1 fall was increased by 11% among those with moderate (relative risk [RR] 1.11, 95% confidence interval [95% CI] = 1.01 - 1.22; P = 0.02) and by 33% among those with severe symptoms (RR 1.33, 95% CI = 1.15 - 1.53; P < 0.001). Further, those with moderate had a 21% (RR 1.21, 95% CI = 1.05 - 1.40; P = 0.01) and those with severe symptoms a 63% (RR 1.63, 95% CI = 1.31 - 2.02; P < 0.001) increased risk of at least 2 falls. Symptoms most strongly associated with falls were urinary urgency, difficulty initiating urination, and nocturia. CONCLUSION Moderate and severe urinary symptoms independently increase the 1-year risk of falls—particularly recurrent falls—in community-dwelling older men. PMID:19154508

Parsons, J. Kellogg; Mougey, Jolee; Lambert, Lori; Wilt, Timothy J.; Fink, Howard A.; Garzotto, Mark; Barrett-Connor, Elizabeth; Marshall, Lynn M.

2011-01-01

438

Breast Cancer Survivors’ Experiences of Lymphedema-Related Symptoms  

PubMed Central

The purpose of this study was to explore and describe breast cancer survivors’ lymphedema-related symptom experiences. As a serious chronic condition from breast cancer treatment, lymphedema, or persistent swelling, is caused by chronic accumulation of lymph fluid in the interstitial spaces of the affected limb or surrounding areas. While significant prevalence of ongoing multiple symptoms have been reported, little is known about how survivors with lymphedema perceive and respond to lymphedema-related symptoms in their daily lives. This study employed a descriptive phenomenological method. Thirty-four participants were recruited in the US. Three in-depth interviews were conducted with each participant; a total of 102 interviews were completed, audio-taped, and transcribed. Interview transcripts and field notes were the data sources for this analysis, which was part of three larger studies. Data were analyzed to identify the essential themes within and across cases. Four essential themes were revealed: living with perpetual discomfort; confronting the unexpected; losing pre-lymphedema being; and feeling handicapped. Participants experienced multiple symptoms on a daily basis. Distress was heightened when women expected symptoms to disappear but instead they remained as a “perpetual discomfort.” Moreover, distress was intensified when symptoms evoked unexpected situations or when symptoms elicited emotional responses powerful enough to change perceived personal identity. Findings suggest that symptom distress may encompass temporal, situational and attributive dimensions. Prospective studies are needed to examine lymphedema-related symptom distress in terms of these dimensions so that more specific interventions can be developed to target distress occurring in each dimension. PMID:19819668

Fu, Mei Rosemary; Rosedale, Mary

2009-01-01

439

Social cognition in schizophrenia: relationships with neurocognition and negative symptoms.  

PubMed

Despite the growing importance of social cognition in schizophrenia, fundamental issues concerning the nature of social cognition in schizophrenia remain unanswered. One issue concerns the strength of the relationships between social cognition and key features of the disorder such as neurocognitive deficits and negative symptoms. The current study employed structural equation modeling to examine three key questions regarding the nature of social cognition in schizophrenia: 1) Are social cognition and neurocognition in schizophrenia better modeled as one or two separate constructs? 2) Are social cognition and negative symptoms in schizophrenia better modeled as one or two separate constructs?, and 3) When social cognition, neurocognition, and negative symptoms are included in a single model, is social cognition more closely related to neurocognition or to negative symptoms? In this cross sectional study, one hundred outpatients with schizophrenia or schizoaffective disorder were administered measures of social cognition, neurocognition, and negative symptoms. A two-factor model that represented social cognition and neurocognition as separate constructs fit the data significantly better than a one-factor model, suggesting that social cognition and neurocognition are distinct, yet highly related, constructs. Likewise, a two-factor model that represented social cognition and negative symptoms as separate constructs fit the data significantly better than a one-factor model, suggesting that social cognition and negative symptoms are distinct constructs. A three-factor model revealed that the relationship between social cognition and neurocognition was stronger than the relationship between social cognition and negative symptoms. The current findings start to provide insights into the structure of social cognition, neurocognition, and negative symptoms in schizophrenia. PMID:17141477

Sergi, Mark J; Rassovsky, Yuri; Widmark, Clifford; Reist, Christopher; Erhart, Stephen; Braff, David L; Marder, Stephen R; Green, Michael F

2007-02-01

440

Correlation of Symptoms to Function in Older Adults with Comorbidity  

PubMed Central

Objectives To (1) describe the relationship between symptom scores and mobility function measures, (2) assess whether symptom scores and disease scores are similarly associated with mobility function, and (3) identify clusters of symptoms that are most strongly associated with functional status in older adults Design Secondary analysis of cross-sectional data from three cohorts Setting Academic medical center Participants 195 community-dwelling subjects with poor flexibility or cardiorespiratory fitness (fitness cohort), 211 female retirement community residents with vertebral fractures (VF cohort), and 61 subjects with Parkinson's disease (PD cohort) Measurements 20-item self-reported symptom scale, 17-item self-reported disease scale, Short Form 36 (SF-36) Physical Functioning Scale, 5-item Nagi Disability scale, 10-meter walk time, supine to stand time Results Symptom scores correlated with mobility function measures (Spearman correlation coefficients range from 0.222 to 0.509) at least as strongly as, if not more strongly than did disease scores. Symptom scores remained associated with functional outcomes after controlling for disease score and demographic variables. Adding symptom scores to models that contained disease scores significantly increased the association with functional outcomes. In the fitness cohort, muscle weakness was the most explanatory single symptom, associated with an average decrease of 17.8 points on the Physical Functioning Scale. A model that included only muscle weakness, pain, and shortness of breath accounted for 21.2% of the variability in the Physical Functioning Score. Conclusion Symptoms represent useful indicators of disability burden in older adults and are promising targets for interventions to improve function in complex patients. PMID:19392960

Whitson, Heather E; Sanders, Linda L; Pieper, Carl F; Morey, Miriam C; Oddone, Eugene Z; Gold, Deborah T; Cohen, Harvey Jay

2009-01-01

441

Anxiety and Depressive Symptoms and Affective Patterns of Tobacco Withdrawal  

PubMed Central

Background The complex concordance and discordance across and within anxiety and depressive symptoms complicates understanding of the relation between emotional symptoms and manifestations of tobacco withdrawal. The goal of this study was to parse the broad variation in anxiety and depressive symptoms into conceptually discrete components and explore their relative predictive influence on affective patterns of acute tobacco withdrawal. Methods We employed a within-participant experimentally-manipulated tobacco abstinence design involving: (i) a baseline visit at which past-week depression and anxiety symptoms were assessed; and (ii) two counterbalanced experimental visits—one after ad lib smoking and one after 16-hours of tobacco abstinence—at which state affect was assessed. Participants were community-dwelling adults (N=187) smoking 10+ cig/day for at least two years without an active mood disorder. Results Anxiety-related general distress symptoms (e.g., tension, nervousness) predicted greater abstinence-induced increases in various negative affective states but not changes in positive affect (?s .17 – .33). Depression-related general distress symptoms (e.g., sadness, worthlessness) predicted greater abstinence-induced increases in acute depressed affect only (?s .24 – .25). Anhedonic symptoms (e.g., diminished interest, lack of pleasure) predicted larger abstinence-induced decreases in acute positive affect only (?s .17 – .20). Anxious Arousal symptoms (e.g., shakiness, heart racing) predicted larger abstinence-induced increases in fatigue and depressive affect (?s .15 – .24). Conclusion Different components of anxiety and depressive symptoms are associated with unique affective patterns of acute tobacco withdrawal. These results provide insight into the affective mechanisms underlying tobacco dependence and could inform smoking cessation treatment approaches tailored to individuals with emotional distress. PMID:23896304

Leventhal, Adam M.; Ameringer, Katherine J.; Osborn, Elly; Zvolensky, Michael J.; Langdon, Kirsten J.

2014-01-01

442

Psychotic symptoms, functioning and coping in adolescents with mental illness  

PubMed Central

Background Psychotic symptoms in the context of psychiatric disorders are associated with poor functional outcomes. Environmental stressors are important in the development of psychosis; however, distress may only be pathogenic when it exceeds an individual’s ability to cope with it. Therefore, one interesting factor regarding poor functional outcomes in patients with psychotic symptoms may be poor coping. This paper aimed to address the question whether 1) psychotic symptoms are associated with poorer functioning and 2) whether poor coping moderated the association. Methods In a clinical case-clinical control study of 106 newly-referred adolescent patients with non-psychotic psychiatric disorders, coping was investigated using the Adolescents Coping Scale. Severity of impairment in socio-occupational functioning was assessed with the Children’s Global Assessment Scale. Results Patients with non-psychotic psychiatric disorders and additional psychotic symptoms (N?=?50) had poorer functioning and were more likely to use avoidance-oriented coping compared to patients with non-psychotic psychiatric disorders without psychotic symptoms (N?=?56). No differences were found with respect to approach-oriented coping. When stratifying for poor/good coping, only those adolescent patients with psychotic symptoms who applied poor coping (i.e. less use of approach-oriented coping styles [OR 0.24, p?symptoms. Due to small subgroups, our analyses could not give definitive conclusions about the question whether coping moderated the association between psychotic symptoms and functioning. Improvement of coping skills may form an important target for intervention that may contribute to better clinical and functional outcomes in patients with psychotic symptoms. PMID:24690447

2014-01-01

443

The influence of depression, anxiety and somatization on the clinical symptoms and treatment response in patients with symptoms of lower urinary tract symptoms suggestive of benign prostatic hyperplasia.  

PubMed

This is the first study to investigate the influence of depression, anxiety and somatization on the treatment response for lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH). The LUTS/BPH patients were evaluated with the Korean versions of the International Prostate Symptom Score (IPSS), the Patient Health Questionnaire-9 (PHQ-9), the 7-item Generalized Anxiety Disorder Scale (GAD-7) and the PHQ-15. The primary endpoint was a responder rate defined by the total score of IPSS (? 7) at the end of treatment. The LUTS/BPH severity was significantly higher in patients with depression (whole symptoms P = 0.024; storage sub-symptom P = 0.021) or somatization (P = 0.024) than in those without, while the quality of life (QOL) was significantly higher in patients with anxiety (P = 0.038) than in those without. Anxious patients showed significantly higher proportion of non-response (odds ratio [OR], 3.294, P = 0.022) than those without, while somatic patients had a trend toward having more non-responders (OR, 2.552, P = 0.067). Our exploratory results suggest that depression, anxiety and somatization may have some influences on the clinical manifestation of LUTS/BPH. Further, anxious patients had a lower response to treatment in patients with LUTS/BPH. Despite of limitations, the present study demonstrates that clinicians may need careful evaluation of psychiatric symptoms for proper management of patients with LUTS/BPH. PMID:25120327

Yang, Yong June; Koh, Jun Sung; Ko, Hyo Jung; Cho, Kang Joon; Kim, Joon Chul; Lee, Soo-Jung; Pae, Chi-Un

2014-08-01

444

The Influence of Depression, Anxiety and Somatization on the Clinical Symptoms and Treatment Response in Patients with Symptoms of Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia  

PubMed Central

This is the first study to investigate the influence of depression, anxiety and somatization on the treatment response for lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH). The LUTS/BPH patients were evaluated with the Korean versions of the International Prostate Symptom Score (IPSS), the Patient Health Questionnaire-9 (PHQ-9), the 7-item Generalized Anxiety Disorder Scale (GAD-7) and the PHQ-15. The primary endpoint was a responder rate defined by the total score of IPSS (? 7) at the end of treatment. The LUTS/BPH severity was significantly higher in patients with depression (whole symptoms P = 0.024; storage sub-symptom P = 0.021) or somatization (P = 0.024) than in those without, while the quality of life (QOL) was significantly higher in patients with anxiety (P = 0.038) than in those without. Anxious patients showed significantly higher proportion of non-response (odds ratio [OR], 3.294, P = 0.022) than those without, while somatic patients had a trend toward having more non-responders (OR, 2.552, P = 0.067). Our exploratory results suggest that depression, anxiety and somatization may have some influences on the clinical manifestation of LUTS/BPH. Further, anxious patients had a lower response to treatment in patients with LUTS/BPH. Despite of limitations, the present study demonstrates that clinicians may need careful evaluation of psychiatric symptoms for proper management of patients with LUTS/BPH. Graphical Abstract PMID:25120327

2014-01-01

445

Evaluation and Treatment of Children and Adolescents with Psychotic Symptoms  

PubMed Central

In recent years, there have been increasing efforts to develop early detection and prevention strategies for patients at risk of the development of psychotic disorders. These efforts have led to improved recognition and characterization of psychotic symptoms in youth. This review focuses on the evaluation of children and adolescents with psychotic symptoms who are experiencing functional impairment but who do not meet current criteria for schizophrenia. For this article, emphasis is placed on the evaluation of symptoms, differential diagnosis, and consideration of potential interventions. PMID:22350543

Algon, Sibel; Yi, James; Calkins, Monica E.; Kohler, Christian; Borgmann-Winter, Karin E.

2012-01-01

446

TODDLERS WITH ELEVATED AUTISM SYMPTOMS SHOW SLOWED HABITUATION TO FACES  

PubMed Central

We explored social information processing and its relation to social and communicative symptoms in toddlers with Autism Spectrum Disorder (ASD) and their siblings. Toddlers with more severe symptoms of autism showed slower habituation to faces than comparison groups; slower face learning correlated with poorer social skills and lower verbal ability. Unaffected toddlers who were siblings of children with ASD also showed slower habituation to faces compared with toddlers without siblings with ASD. We conclude that slower rates of face learning may be an endophenotype of ASD and is associated with more severe symptoms among affected individuals. PMID:20301009

Webb, Sara Jane; Jones, Emily J. H.; Merkle, Kristen; Namkung, Jessica; Toth, Karen; Greenson, Jessica; Murias, Michael; Dawson, Geraldine

2010-01-01

447

Atypical Kawasaki syndrome: how many symptoms have to be present?  

PubMed Central

A 20 year old woman with acute myocardial infarction exhibited a huge aneurysm of the left main coronary artery that was occluded by a large intraluminal thrombus. After exclusion of other vascular or systemic diseases, atypical Kawasaki syndrome was diagnosed. Other major symptoms usually required for this diagnosis were absent. As patients with Kawasaki syndrome in childhood are surviving longer, acute coronary symptoms may occur in young adults, and coronary aneurysms might be the only symptom of atypical Kawasaki syndrome.?? Keywords: coronary artery disease;  myocardial infarction;  atypical Kawasaki syndrome PMID:9470885

Pfafferott, C.; Wirtzfeld, A.; Permanetter, B.

1997-01-01

448

Insomnia in relation to depression and somatic symptoms.  

PubMed

A sample of 358 Kuwaiti volunteer college students responded to the Insomnia Scale, the Somatic Symptoms Inventory, and the Center for Epidemiologic Studies-Depression Scale. The only significant sex difference was in somatic symptoms on which women had a higher mean score than the men. Correlations between scores on the Insomnia Scale and both Depression scales were .51 and .54 and for Somatic Symptoms were .53 and .61 (p < .01) among men and women, respectively. The factor analysis of the intercorrelations yielded a highly loaded general factor for Psychological Disorder in both samples. PMID:17037463

El-Anzi, Freih O

2006-08-01

449

Neuropsychology of reward learning and negative symptoms in schizophrenia.  

PubMed

We used the Iowa Gambling Test (IGT) to examine the relationship of reward learning to both neuropsychological functioning and symptom formation in 65 individuals with schizophrenia. Results indicated that compared to controls, participants with schizophrenia showed significantly reduced reward learning, which in turn correlated with reduced intelligence, memory and executive function, and negative symptoms. The current findings suggested that a disease-related disturbance in reward learning may underlie both cognitive and motivation deficits, as expressed by neuropsychological impairment and negative symptoms in schizophrenia. PMID:25261881

Nestor, Paul G; Choate, Victoria; Niznikiewicz, Margaret; Levitt, James J; Shenton, Martha E; McCarley, Robert W

2014-11-01

450

[Nocturnal symptoms of Parkinson's disease and approaches to their correction].  

PubMed

Seventy-three patients with Parkinson's disease were enrolled. Patients were stratified into 2 groups by the presence (53 patients) or absence (20 patients) of nocturnal symptoms. A control group included 10 healthy people. The most frequent were the following symptoms: nocturia (71.8%), affective disorders (52.4%), akinesia (41.7%) and crampi (30.15%). These symptoms were more pronounced in akinetic/rigid form, greater severity and higher rate of progression of the disease. The positive therapeutic effect of stalevo on the above mentioned disorders was shown. PMID:24430037

Kulua, T K; Fedorova, N V

2013-01-01

451

Clozapine withdrawal symptoms in a Parkinson's disease patient.  

PubMed

Abrupt clozapine withdrawal can cause rebound psychosis and severe somatic symptoms in psychiatric patients. We report on the case of an advanced Parkinson's disease patient who developed myoclonus, tremor, rigidity, hyperreflexia, and stupor after abrupt clozapine withdrawal. The patient's symptoms resolved with treatment with cyproheptadine. This clinical picture suggests serotonergic rebound as an explanation for the patient's symptoms, although other pharmacological mechanisms are possible. Clozapine should be gradually withdrawn over a period of 1 to 2 weeks when possible, and abruptly discontinued only when necessary. PMID:12465085

Zesiewicz, Theresa A; Borra, Sujatha; Hauser, Robert A

2002-11-01

452

PET2OGS: Algorithms to link the static model of Petrel with the dynamic model of OpenGeoSys  

NASA Astrophysics Data System (ADS)

A set of three algorithms named PET2OGS is developed to integrate the static model (Petrel) with the dynamic model (OpenGeoSys). PET2OGS consists of three sub-algorithms that convert finite difference methods (FDMs) grids to finite element methods (FEMs) grids. The algorithms and the workflow of the integration procedures are described in detail. After the proposed algorithms are tested on a variety of grids both in homogeneous and heterogeneous media, the integrated platform of the static and dynamic models is applied to model CO2 storage in a saline aquifer. A successful demonstration of the proposed algorithms proved a robust integration of the platform. With some minor modifications of the algorithms in the part of input and output, the proposed algorithms can be extended to integrate different combinations of FDM-based static models and FEM-based dynamic models beyond the example combination in the paper.

Park, C.-H.; Shinn, Y. J.; Park, Y.-C.; Huh, D.-G.; Lee, S. K.

2014-01-01

453

Operating Systems.  

ERIC Educational Resources Information Center

A computer operating system spans multiple layers of complexity, from commands entered at a keyboard to the details of electronic switching. In addition, the system is organized as a hierarchy of abstractions. Various parts of such a system and system dynamics (using the Unix operating system as an example) are described. (JN)

Denning, Peter J.; Brown, Robert L.

1984-01-01

454

Operational Amplifiers.  

ERIC Educational Resources Information Center

Addresses the introduction of low cost equipment into high school and college physical science classes. Examines the properties of an "ideal" operational amplifier and discusses how it might be used under saturated and non-saturated conditions. Notes the action of a "real" operational amplifier. (TW)

Foxcroft, G. E.

1986-01-01

455

Operator trigonometry  

Microsoft Academic Search

The purpose of the present paper is to survey, from a historical perspective and including some new results, a theory which I will call operator trigonometry. This theory, which is little known, is closely associated with the numerical range W(A) of an operator A. Among the new results is a beautiful connection to numerical linear algebra, in which gradient descent

Karl Gustafson

1994-01-01

456

Operation Success.  

ERIC Educational Resources Information Center

Operation Success is an innovative approach to dealing with potential dropout/high-risk students. The program operates out of the Center for Arts and Technology-Pickering Campus in Northern Chester County, Pennsylvania. The campus offers the students a full-day program, half academic, half vocational. The building of self-esteem and…

Lang, Susan; Teifel, Phyllis

457

Posttraumatic stress disorder symptoms in trauma-exposed college students: The role  

E-print Network

and maintenance of posttraumatic stress disorder (PTSD) symptoms. The present study utilized regression analysis to examine the unique relationships between various trauma-related cognitions and PTSD symptoms after to PTSD symptom severity. Gender and anxiety symptoms were also related to PTSD symptom severity

Liu, Taosheng

458

Insomnia Symptoms, Nightmares, and Suicide Risk: Duration of Sleep Disturbance Matters  

ERIC Educational Resources Information Center

Duration of insomnia symptoms or nightmares was investigated to see if it was related to suicide risk independent of current insomnia symptoms, nightmares, anxiety symptoms, depressive symptoms, and posttraumatic symptoms. The cross-sectional study involved analyses of survey responses from undergraduate students who endorsed either insomnia…

Nadorff, Michael R.; Nazem, Sarra; Fiske, Amy

2013-01-01

459

Somatic Symptoms, but Not Nonsomatic Symptoms, of Depression are Associated with Insulin Resistance: National Health and Nutrition Examination Survey (NHANES) 2005-2010  

E-print Network

, cardiovascular disease, liver disease, kidney disease, or pregnancy. Depressive symptoms were measured usingSomatic Symptoms, but Not Nonsomatic Symptoms, of Depression are Associated with Insulin Resistance Indianapolis While there is a well-established link between depression and type 2 diabetes, depressive symptoms

Zhou, Yaoqi

460

Predictors of Self-Reported Physical Symptoms in Low-Income, Inner-City African American Women: The Role of Optimism, Depressive Symptoms, and Chronic Illness  

ERIC Educational Resources Information Center

In this study we examined the association of optimism and depressive symptoms with self-reported physical symptoms in 241 low-income, inner-city African American women with or without a chronic illness (HIV). Although optimism was not a unique predictor of self-reported physical symptoms over and above depressive symptoms, optimism interacted with…

Jones, Deborah J.; O'Connell, Cara; Gound, Mary; Heller, Laurie; Forehand, Rex

2004-01-01

461

Depression and somatic symptoms scale: a new scale with both depression and somatic symptoms emphasized.  

PubMed

The authors' preliminary study selected 22 items for Depression and Somatic Symptoms Scale (DSSS), including depression subscale (DS) and somatic subscale (SS). The aim of the study was to test reliability and validity of the DSSS. The study enrolled 135 consecutive outpatients (34 male and 101 female) experiencing a major depressive episode (the MDE group), 95 of whom (25 male and 70 female) accepted 1 month of treatment (the treatment group). Diagnosis was confirmed by using the Structured Clinical Interview for 4(th) edition with text revision Diagnostic and Statistical Manual Axis I Disorders. The DSSS and Hamilton Depression Rating Scale (HAMD) were given and evaluated. Cronbach's alpha was used to assess internal consistency. The correlation between the improvement percentage (IP) for the HAMD and the IP for the DSSS was calculated for the treatment group. Factor analysis was performed by using the principal-axis factoring method with promax rotation. Cronbach's alpha values of the DSSS and its subscales ranged from 0.73 to 0.94. Pearson correlation coefficients for the relationship between the DSSS and HAMD ranged from 0.63 to 0.86. In the treatment group, DSSS and HAMD scores were significantly decreased after treatment and the IP for the HAMD and the DSSS were similar and correlated (correlation coefficient = 0.78). The results of the factor analysis demonstrated that most of the items in DS and SS appropriately loaded in Depression and Somatic factors, respectively. The discriminative ability of the DSSS for anxiety comorbidities was not inferior to that of the HAMD. Therefore, the DSSS is reliable and sensitive to the treatment and has acceptable convergent, factorial, and distinct-groups validities. Because it assesses both depression and somatic symptoms, DSSS may overcome the deficiency of other depression scales with few somatic items. PMID:17109704

Hung, Ching-I; Weng, Li-Jen; Su, Yi-Jen; Liu, Chia-Yih

2006-12-01

462

What Are the Signs and Symptoms of Thalassemias?  

MedlinePLUS

... Twitter. What Are the Signs and Symptoms of Thalassemias? A lack of oxygen in the bloodstream causes ... especially with bones in the face) Complications of Thalassemias Better treatments now allow people who have moderate ...

463

What Are the Symptoms of Polycystic Ovary Syndrome (PCOS)?  

MedlinePLUS

... Publications En Español What are the symptoms of PCOS? Skip sharing on social media links Share this: ... addition to the three features used to diagnose PCOS (absence of ovulation, high levels of androgens, and ...

464

Treatments to Relieve Symptoms of Polycystic Ovary Syndrome (PCOS)  

MedlinePLUS

... Publications En Español Treatments to Relieve Symptoms of PCOS Skip sharing on social media links Share this: ... that health care providers recommend for women with PCOS is that they make specific lifestyle changes, such ...

465

Orthopedic Health: Joint Health and Care: Prevention, Symptoms, Diagnosis & Treatment  

MedlinePLUS

... Bar Home Current Issue Past Issues Orthopedic Health Joint Health and Care: Prevention, Symptoms, Diagnosis & Treatment Past ... Exercise helps bone density, improves muscle strength and joint flexibility, and enhances your balance. Take part in ...

466

Disinhibited reactive attachment disorder symptoms impair social judgements from faces  

E-print Network

Disinhibited reactive attachment disorder symptoms impair social judgements from faces Sebastien January 2014 Accepted 5 January 2014 Keywords: Reactive attachment disorder Indiscriminate friendliness with trusting others, yet those with the disinhibited form of reactive attachment disorder (dRAD) can

Caldara, Roberto

467

Organizational Influences on Patient Perceptions of Symptom Management  

PubMed Central

We tested a theoretical model of the relationships of hospital context, nursing unit structure, and patient characteristics to patients’ perceptions of the extent to which nurses met their expectations for management of troubling symptoms. In our sample of 2,720 patients randomly selected from 278 nursing units in 143 hospitals, we found that patient age was positively associated with patients’ perceptions of symptom management. The proportion of registered nurses as caregivers on the unit was not a significant predictor of symptom management, but better work conditions on the unit (nurses’ autonomy, participation in decision-making, and collaboration with other disciplines [relational coordination]) significantly contributed to patients’ perceptions of better symptom management. PMID:19204940

Bacon, Cynthia Thornton; Hughes, Linda C.; Mark, Barbara A

2011-01-01

468

Herbicides: How They Work and the Symptoms They Cause  

E-print Network

Knowing how herbicides work and how to use them safely is important for both agricultural producers and home gardeners. This publication describes the symptoms of each category of herbicides (growth regulators, photosynthesis inhibitors, etc...

Baumann, Paul A.

2008-10-31

469

Routine work environment stress and PTSD symptoms in police officers.  

PubMed

This study examined the relationship between routine work environment stress and posttraumatic stress disorder (PTSD) symptoms in a sample of police officers (N = 180) who were first assessed during academy training and reassessed 1-year later. In a model that included gender, ethnicity, traumatic exposure prior to entering the academy, current negative life events, and critical incident exposure over the last year, routine work environment stress was most strongly associated with PTSD symptoms. We also found that routine work environment stress mediated the relationship between critical incident exposure and PTSD symptoms and between current negative life events and PTSD symptoms. Ensuring that the work environment is functioning optimally protects against the effects of duty-related critical incidents and negative life events outside police service. PMID:19829204

Maguen, Shira; Metzler, Thomas J; McCaslin, Shannon E; Inslicht, Sabra S; Henn-Haase, Clare; Neylan, Thomas C; Marmar, Charles R

2009-10-01

470

Signs and Symptoms for Hantavirus Pulmonary Syndrome (HPS)  

MedlinePLUS

... CDC.gov . Hantavirus Share Compartir Signs & Symptoms for Hantavirus Pulmonary Syndrome (HPS) Due to the small number ... Pathogens Branch 1600 Clifton Rd Atlanta, GA 30333 Hantavirus Hotline (877) 232-3322 (404) 639-1510 800- ...

471

Cortical neuroanatomic correlates of symptom severity in primary progressive aphasia  

E-print Network

Cortical neuroanatomic correlates of symptom severity in primary progressive aphasia D. Sapolsky of a new measure of clinical impairment in primary progressive aphasia (PPA), the Progressive Aphasia Diagnostic Aphasia Examination; CDR Clinical Dementia Rating; CSB Cam- bridge Semantic Battery; ICC

Dickerson, Brad

472

Trajectories of Depression Symptoms among Older Youths Exiting Foster Care.  

PubMed

The purpose of this study was to determine the trajectories of depressive symptoms as older youths from the foster care system mature while also examining the correlates of these trajectories. Data came from a longitudinal study of 404 youths from the foster care system in Missouri, who were interviewed nine times between their 17th and 19th birthdays. Depression was assessed with the Depression Outcomes Module and the Diagnostic Interview Schedule for DSM-IV. Data best fit a model of three trajectory classes, describing young people (1) maintaining low levels of depressive symptoms (never depressed class, 78%), (2) with increasing symptoms (increasing class, 6%), and (3) with decreasing symptoms (decreasing class, 15%). The increasing depression group was mostly male youths who were working or in school; the decreasing class was mostly highly maltreated female youths exiting the foster care system from residential care, with low levels of employment, and in school. Implications for social work practice are discussed. PMID:25076833

Munson, Michelle R; McMillen, Curtis

2010-12-01

473

Symptoms In Children | NIH MedlinePlus the Magazine  

MedlinePLUS

... this page please turn JavaScript on. Feature: Understanding ADHD Symptoms In Children Past Issues / Spring 2014 Table ... hyperactivity, and impulsivity are the key behaviors of ADHD. It is normal for all children to be ...

474

[Sleep difficulties and psychological symptoms in medicine students in Mexico].  

PubMed

The purpose of this study was to describe sleep difficulties in first year medical students associated with psychopathological symptoms. A cross-sectional study in 572 Medicine students, who were assessed by the Symptom Check List-90 (SCL-90), was performed. A 3.5% of students reported having a hard time sleeping, 6.3% had difficulty staying asleep and 11.4% waking up very early. Sleep difficulties were significantly associated with all psychopathological symptoms. The best predictors of sleep difficulties were anxiety, hostility and interpersonal sensitivity. In conclusion, the symptoms associated with stress, anger, worry, cognitive hyperarousal and hypervigilance are the best predictors for sleep difficulties in this population. PMID:23732201

Tafoya, Silvia A; Jurado, María M; Yépez, Norma J; Fouilloux, Mariana; Lara, María C

2013-01-01

475

Brief article The influence of depression symptoms on exploratory  

E-print Network

linked to suicide attempts, interpersonal problems, unemployment, and substance abuse (Kessler et al that depressive symptoms alter action-value computations, causing abnor- mal decision-making in people with higher

Maddox, W. Todd

476

Pharmacological management of behavioral symptoms associated with dementia  

PubMed Central

Dementia is a clinical syndrome with features of neurocognitive decline. Subtypes of dementia include Alzheimer’s, frontotemporal, Parkinson’s, Lewy body disease, and vascular type. Dementia is associated with a variety of neuropsychiatric symptoms that may include agitation, psychosis, depression, and apathy. These symptoms can lead to dangerousness to self or others and are the main source for caregiver burnout. Treatment of these symptoms consists of nonpharmacological and pharmacological interventions. However, there are no Food and Drug Administration-approved medications for the treatment of behavioral and psychological symptoms of dementia. Pharmacological interventions are used off-label. This article reviews the current evidence supporting or negating the use of psychotropic medications along with safety concerns, monitoring, regulations, and recommendations. PMID:25540722

Madhusoodanan, Subramoniam; Ting, Mark Bryan

2014-01-01

477

Are Your Heart Symptoms All in Your Head?  

MedlinePLUS

... page, please enable JavaScript. Are Your Heart Symptoms All in Your Head? For 1 in 5 patients ... Nov. 3, 2014 HealthDay Copyright (c) 2014 HealthDay . All rights reserved. More Health News on: Coronary Artery ...

478

What Are the Signs and Symptoms of Disseminated Intravascular Coagulation?  

MedlinePLUS

... even begin to fail. Signs and Symptoms of Bleeding In DIC, the increased clotting activity uses up ... DIC can cause internal and external bleeding. Internal Bleeding Internal bleeding can occur in your body's organs, ...

479

COPD management: role of symptom assessment in routine clinical practice.  

PubMed

Patients with chronic obstructive pulmonary disease (COPD) present with a variety of symptoms that significantly impair health-related quality of life. Despite this, COPD treatment and its management are mainly based on lung function assessments. There is increasing evidence that conventional lung function measures alone do not correlate well with COPD symptoms and their associated impact on patients' everyday lives. Instead, symptoms should be assessed routinely, preferably by using patient-centered questionnaires that provide a more accurate guide to the actual burden of COPD. Numerous questionnaires have been developed in an attempt to find a simple and reliable tool to use in everyday clinical practice. In this paper, we review three such patient-reported questionnaires recommended by the latest Global Initiative for Chronic Obstructive Lung Disease guidelines, ie, the modified Medical Research Council questionnaire, the clinical COPD questionnaire, and the COPD Assessment Test, as well as other symptom-specific questionnaires that are currently being developed. PMID:24143085

van der Molen, Thys; Miravitlles, Marc; Kocks, Janwillem W H

2013-01-01

480

After a Concussion, Which Teens Will Have Emotional Symptoms?  

MedlinePLUS

... 22 teens had emotional symptoms such as irritability, aggression, anxiety, depression, apathy, frequent mood changes or excessive ... than those without anxiety, while teens with irritability/aggression were 35 percent more likely to self-report ...

481

Menopause Knowledge, Attitude, Symptom and Management among Midlife Employed Women  

PubMed Central

Objectives Midlife women's knowledge, positive attitudes and management toward menopause may improve the quality of peri and post-menopause life. This study was to identify correlations of the knowledge, attitude, symptoms and management toward menopause in middle-aged women. Methods We used a cross-sectional questionnaire study applying to 231 perimenopausal and menopausal women aged from 40 to 59 years old. The completed data of 189 perimenopausal and menopausal women were analyzed through t-test, ANOVA and pearson's correlation coefficient using the SPSS statistical programme. Results The menopausal women showed significantly higher physical symptoms than perimenopausal women. The menopausal women showed significantly higher psychosomatic symptom than perimenopausal women. There was a significant correlation between the menopausal attitude and management. Conclusion This study suggests that the fundamental data of developing midlife women's symptom index (MSI) and providing menopause management could be a strategy to encourage successful menopausal transition in middle-aged women. PMID:25580423

Kwak, Eun Kyung; Park, Hyun Soon

2014-01-01

482

ADHD Symptom Levels and Romantic Relationship Quality in College Students.  

PubMed

Abstract. Objective: The purpose of this study was to examine whether ADHD symptom levels in college undergraduates are associated with poorer romantic relationship quality, and to test whether emotion regulation difficulties, perceived stress, and hostile relationship conflict mediate this association. Participants: The sample consisted of 189 undergraduate students ages 18 to 25. Methods: Self-report measures of ADHD symptoms, relationship quality, and the proposed mediators were collected via online survey from May through August of 2011. Results: Participants who reported clinically significant levels of both hyperactivity-impulsivity and inattentiveness (consistent with ADHD-C) had lower relationship quality than those whose self-reported symptoms indicated no ADHD diagnosis. Further, for women only, both hyperactive/impulsive and inattentive symptom levels were negatively associated with relationship quality. Emotion regulation problems and hostile relationship conflict mediated this association. Conclusion: Findings suggest that ADHD impairs relationship quality among young adults, and suggest mechanisms through which this impairment might occur. PMID:25350392

Bruner, Michael R; Kuryluk, Amanda D; Whitton, Sarah W

2014-10-28

483

Adaptation to vection-induced symptoms of motion sickness  

NASA Technical Reports Server (NTRS)

The effects of repeated exposures to a rotating circular vection drum on the symptoms of motion sickness and tachygastria in humans were investigated. Subjects were sitting in a drum and were exposed to 15 min baseline (no rotation), followed by 15 min drum rotation at 60 deg/s, and, then, by 15 min recovery. Gastric myoelectric activity was continuously recorded with the electrogastrogram. Subjects who were exposed to the drum three times with intervals of 4-24 days all showed symptoms of tachygastria and failed to show an amelioration of motion sickness symptoms. On the other hand subjects who had only 48 h between the three sessions of drum exposure, experienced a reduction in motion-sickness symptoms and in tachygastsria upon repeated exposure to the drum, indicating that training effected a symptomatic and physiological adaptation. It is suggested that preflight adaptation to visual-vestibular sensory mismatch may reduce motion sickness in astronauts.

Stern, Robert M.; Hu, Senqi; Vasey, Michael W.; Koch, Kenneth L.

1989-01-01

484

What Are the Signs and Symptoms of High Blood Pressure?  

MedlinePLUS

... Are the Signs and Symptoms of High Blood Pressure? High blood pressure (HBP) itself usually has no ... for related health problems. Complications of High Blood Pressure When blood pressure stays high over time, it ...

485

Pharmacological management of behavioral symptoms associated with dementia.  

PubMed

Dementia is a clinical syndrome with features of neurocognitive decline. Subtypes of dementia include Alzheimer's, frontotemporal, Parkinson's, Lewy body disease, and vascular type. Dementia is associated with a variety of neuropsychiatric symptoms that may include agitation, psychosis, depression, and apathy. These symptoms can lead to dangerousness to self or others and are the main source for caregiver burnout. Treatment of these symptoms consists of nonpharmacological and pharmacological interventions. However, there are no Food and Drug Administration-approved medications for the treatment of behavioral and psychological symptoms of dementia. Pharmacological interventions are used off-label. This article reviews the current evidence supporting or negating the use of psychotropic medications along with safety concerns, monitoring, regulations, and recommendations. PMID:25540722

Madhusoodanan, Subramoniam; Ting, Mark Bryan

2014-12-22

486

Ser 524 is a phosphorylation site in MUTYH and Ser 524 mutations alter 8-oxoguanine (OG):A mismatch recognition  

PubMed Central

MUTYH-associated polyposis (MAP) is a colorectal cancer predisposition syndrome that is caused by inherited biallelic mutations in the base excision repair (BER) gene, MUTYH. MUTYH is a DNA glycosylase that removes adenine (A) misinserted opposite 8-oxo-7,8-dihydro-2'-deoxyguanosine (OG). In this work, wild type (WT) MUTYH overexpressed using a baculovirus-driven insect cell expression system (BEVS) provided significantly higher levels of enzyme compared to bacterial overexpression. The isolated MUTYH enzyme was analyzed for potential post-translational modifications using mass spectrometry. An in vivo phosphorylation site was validated at Serine 524, which is located in the C-terminal OG recognition domain within the proliferating cell nuclear antigen (PCNA) binding region. Characterization of the phosphomimetic (S524D) and phosphoablating (S524A) mutants together with the observation that Ser 524 can be phosphorylated suggest that this residue may play an important regulatory role in vivo by altering stability and OG:A mismatch affinity. PMID:20724227

Kundu, Sucharita; Brinkmeyer, Megan K.; Eigenheer, Richard A.; David, Sheila S.

2010-01-01

487

Obsessive compulsive symptoms at initial presentation of adolescent eating disorders  

Microsoft Academic Search

An association between obsessive compulsive disorder and eating disorders has often been reported in the literature. It has\\u000a been suggested that the association may be accounted for by depression, starvation or family factors but the literature remains\\u000a inconclusive. In this study self-report scales were used to measure eating attitudes, obsessional symptoms, depressive symptoms\\u000a and family functioning in an eating disordered

E. Cassidy; M. Allsopp; T. Williams

1999-01-01

488

Management of Non-Pain Symptoms in Pediatric Palliative Care  

Microsoft Academic Search

The majority of children dying from a life-limiting condition suffer from distressing symptoms during their last weeks of life. The provision of current state-of-the-art symptom control is paramount for any health care professional working with dying children, but treatment guidelines are sparse. This article reviews the management of integrative and pharmacological therapies for acute seizure control, anorexia, death rattle, dyspnea,

Stefan J. Friedrichsdorf; John J. Collins

2007-01-01

489

Associations Between Physical Activity and Postpartum Depressive Symptoms  

PubMed Central

Abstract Background Postpartum women are at increased risk for developing depression, which can contribute to the ill health of the mother and her family. Previous research indicates that mothers who are physically active during leisure experience lower levels of postpartum depressive symptoms than do inactive mothers. The objective of this investigation was to examine the associations between total and domain-specific moderate to vigorous physical activity (MVPA) and depressive symptoms postpartum. Methods Data were obtained from 550 women who participated in the Pregnancy, Infection, and Nutrition (PIN) Postpartum Study, a prospective cohort of mothers who delivered liveborn infants from October 2002 to December 2005 in North Carolina. Three-month postpartum MVPA was investigated as a predictor of 12-month postpartum depressive symptoms. Results Those who participated in MVPA had two times the odds of developing elevated depressive symptoms at 12 months postpartum than those with no MVPA (odds ratio [OR] 2.00, 95% confidence interval [CI] 0.71-6.75). Different associations were suggested when examining domain-specific MVPA. Those participating in adult and child care and indoor household MVPA at 3 months postpartum had more than double the odds of developing elevated depressive symptoms at 12 months postpartum (OR 2.66, 95% CI 1.03, 8.11 and OR 2.72, 95% CI 0.96-10.18, respectively). Work MVPA conferred a doubling of the odds (OR 1.95, 95% CI 0.46-7.13), but recreational and outdoor household MVPA showed no associations with depressive symptoms. Conclusions Associations between MVPA and depressive symptoms differed by domain among postpartum women. Future studies of postpartum depressive symptoms should explore reasons for differences in physical activity by domain. PMID:21668353

Siega-Riz, Anna Maria; Evenson, Kelly R.; Herring, Amy H.; Dole, Nancy; Gaynes, Bradley N.

2011-01-01

490

The 24-month course of manic symptoms in children  

PubMed Central

Objectives The Longitudinal Assessment of Manic Symptoms (LAMS) study was designed to investigate phenomenology and establish predictors of functional outcomes in children with elevated manic symptoms. The purpose of this series of analyses was to determine whether the participants demonstrated different trajectories of parent-reported manic and biphasic symptoms over the first 24 months of follow-up and to describe the clinical characteristics of the trajectories. Methods The 707 participants were initially aged 6–12 years and ascertained from outpatient clinics associated with the four university-affiliated LAMS sites. There were 621 children whose parents/guardians’ ratings scored ? 12 on the Parent General Behavior Inventory–10-item Mania Form (PGBI-10M) and a matched random sample of 86 children whose parents/guardians’ ratings scored ? 11 on the PGBI-10M. Participants were seen every six months after the baseline and their parents completed the PGBI-10M at each visit. Results For the whole sample, manic symptoms decreased over 24 months (linear effect B = -1.15, standard error = 0.32, t = -3.66, p < 0.001). Growth Mixture Modeling revealed four unique trajectories of manic symptoms. Approximately 85% of the cohort belonged to two classes in which manic symptoms decreased. The remaining ? 15% formed two classes (high and rising and unstable) characterized by the highest rates of diagnostic conversion to a bipolar disorder (all p-values < 0.001). Conclusions Outcomes are not uniform among children with symptoms of mania or high risk for mania. A substantial minority of clinically referred children shows unstable or steadily increasing manic symptoms, and these patterns have distinct clinical correlates. PMID:23799945

Findling, Robert L; Jo, Booil; Frazier, Thomas W; Youngstrom, Eric A; Demeter, Christine A; Fristad, Mary A; Birmaher, Boris; Kowatch, Robert A; Arnold, Eugene; Axelson, David A; Ryan, Neal; Hauser, Jessica C; Brace, Daniel J; Marsh, Linda E; Gill, Mary Kay; Depew, Judith; Rowles, Brieana M; Horwitz, Sarah McCue

2013-01-01

491

Smartphone data as objective measures of bipolar disorder symptoms.  

PubMed

The daily electronic self-monitoring Smartphone software "MONARCA" was used by 17 patients with bipolar disorder for 3 consecutive months. Patients were rated fortnightly using Hamilton Depression rating Scale 17 items (HDRS-17) and Young Mania rating Scale (YMRS) (102 ratings) with blinding for Smartphone data. Objective Smartphone measures such as physical and social activity correlated with clinically rated depressive symptoms. Self-monitored depressive symptoms correlated significantly with HDRS-17 items score. PMID:24679993

Faurholt-Jepsen, Maria; Frost, Mads; Vinberg, Maj; Christensen, Ellen Margrethe; Bardram, Jakob E; Kessing, Lars Vedel

2014-06-30

492

Depressive symptoms over the course of HIV infection before AIDS  

Microsoft Academic Search

The objective of this study was to describe the prevalence and course of depressive symptoms before AIDS in HIV-infected homosexual men. A descriptive and comparative analysis of data from HIV-infected and-uninfected homosexual men in the Multicenter AIDS Cohort Study was performed. The Center for Epidemiologic Studies Depression Scale (CES-D) was the primary measure of depressive symptoms. The prevalence of depressive

C. G. Lyketsos; D. R. Hoover; M. Guccione; G. J. Treisman; M. A. Dew; J. Wesch; E. G. Bing

1996-01-01

493

Brain structural signatures of negative symptoms in depression and schizophrenia  

E-print Network

the analysis of the National Institute of Mental Health Clinical Antipsychotic Trials of Intervention 77 Effectiveness (CATIE) schizophrenia trial, negative symptoms have greater impact on functioning 78 than positive or any other symptoms (2). Moreover... 134 Thirteen depressed participants were taking antidepressants with the following daily dose ranges: 135 citalopram 30-60 mg, mirtazapine 30-45 mg, venlafaxine 75-225 mg. Nearly all patients with 136 schizophrenia were on atypical antipsychotic...

Chuang, Jie-Yu; Murray, Graham K.; Metastasio, Antonio; Segarra, Nuria; Tait, Roger; Spencer, Jenny; Ziauddeen, Hisham; Dudas, Robert B.; Fletcher, Paul C.; Suckling, John

2014-08-27

494

Dissociative symptoms and amnesia in Dutch concentration camp survivors  

Microsoft Academic Search

We examined to what extent dissociative phenomena in concentration camp survivors are related to post-traumatic stress symptoms. Self-reports of amnesia for traumatic war events and other dissociative experiences were studied in a sample of 31 Dutch survivors of World War II (WWII) Japanese concentration camps. Seventeen survivors treated for war-related psychiatric symptoms were compared to 14 concentration camp survivors who

Harald Merckelbach; Theo Dekkers; Ineke Wessel; Anne Roefs

2003-01-01

495

Symptom Dimensions in OCD: Developmental and Evolutionary Perspectives  

Microsoft Academic Search

At the present time, in the absence of definitive etiological markers of vulnerability for obsessive-compulsive disorder (OCD),\\u000a obsessive-compulsive (OC) symptom dimensions appear to offer a fruitful point of orientation. The complex clinical presentation\\u000a of OCD can be summarized using a few consistent and temporally stable symptom dimensions. These can be understood as a spectrum\\u000a of potentially overlapping vulnerabilities that are

James F. Leckman; David Mataix-Cols; Maria Conceição do Rosario-Campos

496

Effect of Physical Activity on Menopausal Symptoms among Urban Women  

Microsoft Academic Search

NELSON, D. B., M. D. SAMMEL, E. W. FREEMAN, H. LIN, C. R. GRACIA, and K. H. SCHMITZ. Effect of Physical Activity on Menopausal Symptoms among Urban Women. Med. Sci. Sports Exere., Vol. 40, No. 1, pp. 50-58, 2008. Purpose: To determine whether physical activity, measured by expended kilocalories per week (kcal-wk-1), decreases the risk of menopausal symptoms among African

DEBORAH B. NELSON; MARY D. SAMMEL; ELLEN W. FREEMAN; HUI LIN; CLARISA R. GRACIA; KATHRYN H. SCHMITZ

2007-01-01

497

Friendship and Internalizing Symptoms Among Children and Adolescents with ASD  

Microsoft Academic Search

Anxiety and depression are common among children and adolescents with autism spectrum disorders (ASD), highlighting a need\\u000a to identify factors that protect against these symptoms. Among typically developing children, friendships are protective,\\u000a and lead to better emotional outcomes. The current study examined a large, well-characterized sample of children and adolescents\\u000a with ASD to examine the relations among friendship, ASD symptom

Micah O. MazurekStephen; Stephen M. Kanne

2010-01-01